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Sample records for philadelphia electric strives

  1. The long road back for a reborn Philadelphia Electric

    International Nuclear Information System (INIS)

    Anon.

    1990-01-01

    On 31 March 1987, the US NRC ordered Philadelphia Electric to shut down its Peach Bottom BWR station because of operator inattentiveness. Since then Philadelphia Electric has undergone the most complete transformation of corporate and nuclear management of any US utility. Everyone in direct line supervision was replaced, from the chairman of the board down to shift supervisors. Nuclear operations were completely reorganized and a dedicated nuclear group formed. Procedures were rewritten and operator training and career development upgraded. Plant maintenance and housekeeping have been raised to new levels of excellence. It has been a long road back for Philadelphia Electric. But all major goals are now being met and a corporate culture is being developed focused on excellence in nuclear operations. (author)

  2. Shutdown risk management applied at Philadelphia Electric Company

    International Nuclear Information System (INIS)

    Dagan, William J.; True, Douglas E.; Wilson, Thomas; Truax, William

    2004-01-01

    The development and implementation of an effective risk management program requires basic risk or safety knowledge and the conversion of such information into effective management tools. ERIN Engineering and Research, Inc., under contract to the Electric Power Research Institute, has developed an effective program. Outage Risk Assessment and Management (ORAM), to provide plant and management personnel with understandable results of shutdown risk studies. With this tool, the impact of plans and decision options can be readily determined and displayed for the decision maker. This paper describes these methods and their application to the Limerick Nuclear Station of Philadelphia Electric Company. It also sets forth a broader application of these methods to include support of management decisions at-power and following forced outages. The result is an integrated risk management framework which can allow management and technical personnel to utilize readily available and understandable risk insights to optimize each activity. This paper addresses the resolution of several key issues in detail: How was the ORAM risk management method employed to represent the existing plant shutdown procedures and policies? How did the ORAM risk management method enhance the decision-making ability of the outage management staff? How was the ORAM software efficiently integrated with the outage scheduling software? How is quantitative risk information generated and used for outage planning and control? The ORAM risk management philosophy utilizes a series of colors to depict various risk configurations. Each such configuration has associated with it clear guidance. By modifying the conditions existing in the plant it is possible to impact the type of risk being encountered as well as the guidance which is appropriate for that period. In addition, the duration of a particular configuration can be effectively managed to reduce the overall risk impact. These are achieved with minimal

  3. Creating a business environment in inventory management - The Philadelphia Electric Company experiences

    International Nuclear Information System (INIS)

    Franks, A.J.; Birch, H.

    1992-01-01

    Philadelphia Electric Company's (PECo's) Nuclear Engineering and Services Department was asked to develop a (non-fuel) inventory management philosophy that will optimize inventory dollars at Peach Bottom atomic power station and Limerick generating station. The ultimate goal of the project is to maximize the potential for the correct parts being available at the lowest possible level of investment. There are many factors that make the management of maintenance, repair, and operating (MRO) supply inventories more complicated than managing finished goods, work-in-progress, or raw materials. Determining correct inventory levels for nuclear power plants is complicated by the irregular demand for spare parts and the cyclic nature of demand caused by refueling outages. Based on the information collected, it was determined that PECo's nuclear group needed to develop policies and strategies to address the following issues: (1) inventory classification based on part criticality, usage, and demand forecast; (2) item level ordering policies based on classification system; (3) inventory performance management; and (4) management of obsolete/surplus parts. Currently, policies are being developed to manage surplus and obsolete materials. Opportunities are being explored regarding the potential capitalization of critical components and parts. The policies established for classification, ordering policies, and performance management are being translated into work processes via common procedures and guidelines

  4. Striving for excellence

    International Nuclear Information System (INIS)

    Vaughn, G.E.

    1986-01-01

    With guidance and assistance from the Institute of Nuclear Power Operations (INPO), nuclear utilities are striving for excellence by making steady improvements in industry performance indicators. Duke Power Company has solidly committed to support the industry's effort to obtain higher standards of excellence. Dedicated, highly trained employees, who are motivated to making it happen, carry out this commitment within a management framework which includes: 1) top management support and direct involvement; 2) a strategy to achieve excellence over the long run; 3) a nuclear management priority structure; and 4) a goals program

  5. Undergraduate Program: Philadelphia

    Science.gov (United States)

    Betsock, Lori

    2008-08-01

    Undergraduate chemical science students—join us in Philadelphia on August 17 and 18, 2008, for an educational and career-oriented program designed specifically for you. Attend symposia about global climate change and clean energy; hear Nobel Laureate F. Sherwood Rowland speak about his fascinating career, "A Life in Tracer Chemistry". Weigh options for your future by attending the Graduate School Reality Check and graduate school recruiting events. All events will take place in the Sheraton Philadelphia City Center at 17th and Race Streets, except the Undergraduate Poster Sessions and Sci-Mix, which will be held in the Pennsylvania Convention Center.

  6. Philadelphia and the Tomato.

    Science.gov (United States)

    Smith, Andrew F.; Kling, Tatiana

    This booklet describes for elementary students the many contributions of people, traveling many places, over many years to bring the tomato to Philadelphia. The booklet includes the following: (1) "Introduction to the Tomato"; (2) "Where Does the Tomato Come From?"; (3) "The Spanish Tomato"; (4) "The Philadelphia…

  7. School Closings in Philadelphia

    Science.gov (United States)

    Jack, James; Sludden, John

    2013-01-01

    In 2012, the School District of Philadelphia closed six schools. In 2013, it closed 24. The closure of 30 schools has occurred amid a financial crisis, headlined by the district's $1.35 billion deficit. School closures are one piece of the district's plan to cut expenditures and close its budget gap. The closures are also intended to make…

  8. Virtue Acquisition: The Paradox of Striving

    Science.gov (United States)

    Snow, Nancy

    2016-01-01

    Aristotelian-inspired accounts of virtue acquisition stress guided practice and habituated action to develop virtue. This emphasis on action can lead to the "paradox of striving". The paradox occurs when we try too hard to act well and thereby spoil our efforts. I identify four forms of striving--forcing, impulsivity, overthinking, and…

  9. The urban forests of Philadelphia

    Science.gov (United States)

    David J. Nowak; Allison R. Bodine; Robert Hoehn; Alexis Ellis; Sarah C. Low; Lara A. Roman; Jason G. Henning; Emily Stephan; Tom Taggert; Ted. Endreny

    2016-01-01

    An analysis of the urban forest in Philadelphia, Pennsylvania, reveals that this city has an estimated 2.9 million trees (encompassing all woody plants greater than 1 inch diameter at breast height [d.b.h]) with tree canopy that covers 20 percent of the city. The most common tree species are spicebush, black cherry, ash, tree-of-heaven, and boxelder, but the most...

  10. Molecular Analysis Research at Community College of Philadelphia

    Science.gov (United States)

    2015-09-21

    YOUR FORM TO THE ABOVE ADDRESS. Community College of Philadelphia Community College of Philadelphia 1700 Spring Garden Street Philadelphia, PA 19130...Approved for Public Release; Distribution Unlimited Final Report: Molecular Analysis Research at Community College of Philadelphia The views, opinions...Molecular Analysis Research at Community College of Philadelphia Report Title AXIMA Assurance mass spectrometer, Leica DMI-8 fluorescent microscope

  11. Electrical injury

    Science.gov (United States)

    ... RS, Gausche-Hill M, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice. 9th ed. Philadelphia, PA: Elsevier; 2018:chap 134. Price LA, Loiacono LA. Electrical and lightning injury. In: Cameron JL, Cameron AM, eds. Current Surgical ...

  12. Comprehensive District Reform: Philadelphia's Grand Experiment.

    Science.gov (United States)

    Useem, Elizabeth; Balfanz, Robert

    2002-01-01

    This report describes "Philadelphia's Grand Experiment" in comprehensive school district reform, from its conception through its initial months of implementation. In 2001, as part of the remedy for low student performance, the governor ordered the state to take over governance of the Philadelphia School District, with a substantial…

  13. Striving for Economic and Political Sustainability

    OpenAIRE

    Rothman, Andy

    2010-01-01

    Hu Jintao, China’s president and Communist Party chief, is asking his government to abandon its 25-year-old policy of striving for the fastest possible economic growth, regardless of the costs to society and the environment. Instead, he wants China to balance sustainable growth with a programme to redress the many negative consequences of two decades of 9%-plus GDP growth. Although we do not expect Hu to fix China’s health care system or to deliver a clean and green environment in just five y...

  14. Striving for balance between caring and restraint

    DEFF Research Database (Denmark)

    Moberg, Julie Y; Larsen, Dorte; Brødsgaard, Anne

    2017-01-01

    with 14 young adults were conducted. RESULTS: The essence of the phenomenon of having a parent with multiple sclerosis was synthesized into 'Striving for balance between caring and restraint' from two themes 'caring' and 'restraint' and eight subthemes. Participants' experiences of caring for parents...... that one of the greatest challenges of having a parent with multiple sclerosis is achieving a balance between caring for others and asserting one's own desires. RELEVANCE TO CLINICAL PRACTICE: Health care professionals can support the family by encouraging family members to participate in consultations...

  15. Maximizing Green Infrastructure in a Philadelphia Neighborhood

    OpenAIRE

    Kate Zidar; Timothy A. Bartrand; Charles H. Loomis; Chariss A. McAfee; Juliet M. Geldi; Gavin J. Rigall; Franco Montalto

    2017-01-01

    While the Philadelphia Water Department (PWD) is counting on Green Stormwater Infrastructure (GI) as a key component of its long-term plan for reducing combined sewer overflows, many community stakeholders are also hoping that investment in greening can help meet other ancillary goals, collectively referred to as sustainable redevelopment. This study investigates the challenges associated with implementation of GI in Point Breeze, a residential neighborhood of South Philadelphia. The project ...

  16. African Diaspora Movement Arts in Philadelphia: A Beginning Resource List. Philadelphia Folklore Project Working Papers #10.

    Science.gov (United States)

    Brown-Danquah, Benita Binta

    This guide provides history, format, contact names, addresses, and phone numbers of some African dance and African American marching units in Philadelphia (Pennsylvania). The working papers are divided into two categories. "Part One: Movements of African Dance in Philadelphia" begins with a sensitive, detailed explanation of the…

  17. Primary Healthcare Spending : Striving for Equity under Fiscal ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Primary Healthcare Spending : Striving for Equity under Fiscal Federalism. Couverture du livre Primary Healthcare Spending: Striving for Equity under Fiscal Federalism. Auteur(s) : Okore Apia Okorafor. Maison(s) d'édition : UCT Press, CRDI. 1 avril 2010. ISBN : 9781919895215. 200 pages. e-ISBN : 9781552504895.

  18. Making Health Easier: Active Living in Philadelphia, PA PSA (:60)

    Centers for Disease Control (CDC) Podcasts

    Making communities bike-friendly can help reduce traffic congestion and increase the physical activity of residents. Learn how one Philadelphia resident worked with his community to make Philadelphia a more bike-friendly city.

  19. Japanese maintenance centres strive for greater realism

    International Nuclear Information System (INIS)

    Nedderman, J.

    1987-01-01

    Japanese utilities have devoted considerable efforts to ensuring that realistic plant conditions are simulated at their maintenance centres. In some centres, eg that of Kansai Electric Power Co, realism extends to difficult access, limited lighting and restricted ventilation. (author)

  20. Philadelphia's Renaissance Schools Initiative after Four Years

    Science.gov (United States)

    Stratos, Kati; Wolford, Tonya; Reitano, Adrienne

    2015-01-01

    In 2010-2011, the School District of Philadelphia (the District) launched its Renaissance Schools Initiative, a program designed to dramatically improve student achievement in the District's lowest performing schools. Some schools became Promise Academies, based on the federal turnaround model, and remained District-operated neighborhood schools.…

  1. Transforming the energy system: Why municipalities strive for energy self-sufficiency

    International Nuclear Information System (INIS)

    Engelken, Maximilian; Römer, Benedikt; Drescher, Marcus; Welpe, Isabell

    2016-01-01

    Despite evidence that a rising number of municipalities in Germany are striving for energy self-sufficiency, there is little understanding of the driving factors behind this development. We investigate economic, ecological, social and energy system related factors that drive municipalities to strive for energy self-sufficiency with a focus on electricity supply. The empirical data for this study is based on insights generated through expert interviews (N =19) with mayors, energy experts and scientists as well as a quantitative study among mayors and energy officers (N =109) of German municipalities. Results show that environmental awareness, tax revenues and greater independence from private utilities are positively related to the mayors’ attitude towards the realization of energy self-sufficiency. Furthermore, citizens, the political environment, the mayor's political power, and his/her financial resources are relevant factors for a municipality striving for energy self-sufficiency. Policymakers need to decide whether or not to support mayors in this development. For suitable policy interventions, the results suggest the importance of an integrated approach that considers a combination of identified factors. Finally, we propose a morphological box to structure different aspects of energy self-sufficiency and categorize the present study. - Highlights: • Municipalities striving for energy self-sufficiency can play a key role in the transition of the energy system. • Tax revenues and environmental awareness main drivers behind mayors’ attitude towards energy self-sufficiency. • Citizens and the political environment main influencers of mayors striving for energy self-sufficiency. • 19 expert interviews analyzed for the framework of the study based on the theory of planned behavior (TPB). • 109 mayors and energy officers participated in the quantitative main survey.

  2. Primary Healthcare Spending: Striving for Equity under Fiscal ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2010-04-01

    Apr 1, 2010 ... Book cover Primary Healthcare Spending: Striving for Equity under Fiscal Federalism ... Primary Healthcare Spending is an important reference for ... field of health policy and health economics, agencies involved in providing ...

  3. Striving to Achieve Gender Equity in Education: A Zimbabwean ...

    African Journals Online (AJOL)

    Striving to Achieve Gender Equity in Education: A Zimbabwean Experience ... of all forms of inequalities in its society, including gender inequalities in education. ... implementation of policies meant to promote education of girls and women.

  4. Molecular diagnostic of the philadelphia chromosome

    International Nuclear Information System (INIS)

    Campos Rudin, M.; Cuenca Berger, P.; Gutierrez Espeleta, G.; Jimenez Cruz, G.; Montero Umana, C.; Vazquez Castillo, L.; Ramon Ortiz, M.

    1998-01-01

    The importance that has to confirm the presence or absence of the chromosome Philadelphia in the diagnostic and follow up of the patient affected with chronic myeloid leukemia and other leukemia. It is considered necessary to implement the molecular diagnostic in Costa Rica. They studied 32 patient affected by Chronic Myeloid Leukemia, 7 by other Myeloproliferative Chronic Disorders and 2 by Myelodysplastic Syndrome. It utilized the sound Trans probe-1 (Oncogene Science, Inc), which was marked with radioactivity ( 32 P) or chemiluminescence (digoxigenin). Of the 32 cases affected by L mc, in 28 it was possible to carry out the molecular analysis detecting the characteristic translocation of the chromosome Philadelphia among the Mbcr/c-ABL genes in 21 (75%) of the patients, in 7 (25%) the rearrangement was not found. In seven of the nine affected by other sufferings it was possible to obtain results, 3 that turned out to be positive for the rearrangement among Mbcr/c-ABL and 4 normal. In all the cases, they obtained results marking the sound with radioactivity. However, they tested the marks with digoxigenin in seven of the patients, as an methodological alternative for the laboratories that lacks the requirements to work with radiation. The results obtained were identical. (S. Grainger) [es

  5. Maximizing Green Infrastructure in a Philadelphia Neighborhood

    Directory of Open Access Journals (Sweden)

    Kate Zidar

    2017-10-01

    Full Text Available While the Philadelphia Water Department (PWD is counting on Green Stormwater Infrastructure (GI as a key component of its long-term plan for reducing combined sewer overflows, many community stakeholders are also hoping that investment in greening can help meet other ancillary goals, collectively referred to as sustainable redevelopment. This study investigates the challenges associated with implementation of GI in Point Breeze, a residential neighborhood of South Philadelphia. The project team performed a detailed study of physical, social, legal, and economic conditions in the pilot neighborhood over the course of several years, culminating in the development of an agent-based model simulation of GI implementation. The model evaluates a whether PWD’s GI goals can be met in a timely manner, b what kinds of assumptions regarding participation would be needed under different theoretical GI policies, and c the extent to which GI could promote sustainable redevelopment. The model outcomes underscore the importance of private land in helping PWD achieve its GI goals in Point Breeze. Achieving a meaningful density of GI in the neighborhoods most in need of sustainable redevelopment may require new and creative strategies for GI implementation tailored for the types of land present in those particular communities.

  6. Dynamics of Networks if Everyone Strives for Structural Holes

    NARCIS (Netherlands)

    Buskens, Vincent; Rijt, Arnout van de

    2008-01-01

    When entrepreneurs enter structural holes in networks, they can exploit the related benefits. Evidence for these benefits has steadily accumulated. The authors ask whether those who strive for such structural advantages can maintain them if others follow their example. Burt speculates that they

  7. The motivational properties of hope in goal striving

    NARCIS (Netherlands)

    Nelissen, R.M.A.

    2017-01-01

    We argue that hope is not an expectancy based on beliefs about pathways to desired goals and personal capacities to act on them, but an experience of the mere possibility of a desired outcome. We propose that in the latter sense, hope has unique motivational consequences for goal striving.

  8. Making Health Easier: Active Living in Philadelphia, PA PSA (:60)

    Centers for Disease Control (CDC) Podcasts

    2013-06-07

    Making communities bike-friendly can help reduce traffic congestion and increase the physical activity of residents. Learn how one Philadelphia resident worked with his community to make Philadelphia a more bike-friendly city.  Created: 6/7/2013 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 6/7/2013.

  9. Time's Up: Applying Teacher Management Skills to Solving Philadelphia's Problems

    Science.gov (United States)

    Lax, Zach

    2013-01-01

    Teachers are natural problem solvers, and they should be using this quality to their advantage when it comes to solving the systemic issues that plague Philadelphia's education system. Many of the articles in this issue have already gone into great detail about what is happening in Philadelphia. Torch Lytle has provided a summary of the recent…

  10. Strategies for Talent Management: Greater Philadelphia Companies in Action

    Science.gov (United States)

    Council for Adult and Experiential Learning (NJ1), 2008

    2008-01-01

    Human capital is one of the critical issues that impacts the Greater Philadelphia region's ability to grow and prosper. The CEO Council for Growth (CEO Council) is committed to ensuring a steady and talented supply of quality workers for this region. "Strategies for Talent Management: Greater Philadelphia Companies in Action" provides…

  11. The Philadelphia Glaucoma Detection and Treatment Project

    Science.gov (United States)

    Waisbourd, Michael; Pruzan, Noelle L.; Johnson, Deiana; Ugorets, Angela; Crews, John E.; Saaddine, Jinan B.; Henderer, Jeffery D.; Hark, Lisa A.; Katz, L. Jay

    2016-01-01

    Purpose To evaluate the detection rates of glaucoma-related diagnoses and the initial treatments received in the Philadelphia Glaucoma Detection and Treatment Project, a community-based initiative aimed at improving the detection, treatment, and follow-up care of individuals at risk for glaucoma. Design Retrospective analysis. Participants A total of 1649 individuals at risk for glaucoma who were examined and treated in 43 community centers located in underserved communities of Philadelphia. Methods Individuals were enrolled if they were African American aged ≥50 years, were any other adult aged ≥60 years, or had a family history of glaucoma. After attending an informational glaucoma workshop, participants underwent a targeted glaucoma examination including an ocular, medical, and family history; visual acuity testing, intraocular pressure (IOP) measurement, and corneal pachymetry; slit-lamp and optic nerve examination; automated visual field testing; and fundus color photography. If indicated, treatments included selective laser trabeculoplasty (SLT), laser peripheral iridotomy (LPI), or IOP-lowering medications. Follow-up examinations were scheduled at the community sites after 4 to 6 weeks or 4 to 6 months, depending on the clinical scenario. Main Outcome Measures Detection rates of glaucoma-related diagnoses and types of treatments administered. Results Of the 1649 individuals enrolled, 645 (39.1%) received a glaucoma-related diagnosis; 20.0% (n = 330) were identified as open-angle glaucoma (OAG) suspects, 9.2% (n = 151) were identified as having narrow angles (or as a primary angle closure/suspect), and 10.0% (n = 164) were diagnosed with glaucoma, including 9.0% (n = 148) with OAG and 1.0% (n = 16) with angle-closure glaucoma. Overall, 39.0% (n = 64 of 164) of those diagnosed with glaucoma were unaware of their diagnosis. A total of 196 patients (11.9%) received glaucoma-related treatment, including 84 (5.1%) who underwent LPI, 13 (0.8%) who underwent SLT

  12. Gentrification and Residential Mobility in Philadelphia.

    Science.gov (United States)

    Ding, Lei; Hwang, Jackelyn; Divringi, Eileen

    2016-11-01

    Gentrification has provoked considerable controversy surrounding its effects on residential displacement. Using a unique individual-level, longitudinal data set, this study examines mobility rates and residential destinations of residents in gentrifying neighborhoods during the recent housing boom and bust in Philadelphia for various strata of residents and different types of gentrification. We find that vulnerable residents, those with low credit scores and without mortgages, are generally no more likely to move from gentrifying neighborhoods compared with their counterparts in nongentrifying neighborhoods. When they do move, however, they are more likely to move to lower-income neighborhoods. Residents in gentrifying neighborhoods at the aggregate level have slightly higher mobility rates, but these rates are largely driven by more advantaged residents. These findings shed new light on the heterogeneity in mobility patterns across residents in gentrifying neighborhoods and suggest that researchers should focus more attention on the quality of residential moves and nonmoves for less advantaged residents, rather than mobility rates alone.

  13. Striving for Sustainable Organizational Changes in Hypercomplex Settings

    DEFF Research Database (Denmark)

    Neisig, Margit

    2017-01-01

    , and to enable organizational development (OD) to address the big question of the day. Originality/Value: The article adds to organizational development, HRM, NPM and performance management by providing a conception on, what it takes to become reflective of a higher order as to strive towards sustainability....../methodology/approach 1. Clarifying this articles understanding of the interrelated emergence of human resource management, new public management and performance management systems as producing a shared reservoir of semantics shaping other social systems through translation processes, structural coupling and coevolution...... conceptualization of different types of PMS to the levels of re-entry conceptualized in step 2 Findings This allows revealing the interplay of different types of PMS systems and whether they hinder or stabilize this long and vulnerable chain of re-entries needed in the striving for sustainable organizational...

  14. Nutrition environments in corner stores in Philadelphia.

    Science.gov (United States)

    Cavanaugh, Erica; Mallya, Giridhar; Brensinger, Colleen; Tierney, Ann; Glanz, Karen

    2013-02-01

    To examine the availability, quality, and price of key types of healthy and less-healthy foods found in corner stores in low-income urban neighborhoods and the associations between store characteristics and store food environments. A sample of 246 corner stores was selected from all corner stores participating in the Philadelphia Healthy Corner Store Initiative (HCSI). The Nutrition Environment Measures Survey for Corner Stores (NEMS-CS) was used to assess the availability, quality, and price of foods and beverages in 11 common categories between February and May, 2011. NEMS-CS measures were completed in 233 stores, 94.7% of the 246 stores approached. The healthier options were significantly less available in all food categories and often more expensive. Baked goods, bread, chips and cereals were sold at nearly all stores, with significantly fewer offering low-fat baked goods (5.7%, pbread (56.2%, pfood environment and dietary choices among low-income urban populations. Availability of certain healthier foods could be improved. Copyright © 2012 Elsevier Inc. All rights reserved.

  15. Anticipated emotions and effort allocation in weight goal striving.

    Science.gov (United States)

    Nelissen, Rob M A; de Vet, Emely; Zeelenberg, Marcel

    2011-02-01

    This study aimed to investigate the influence of anticipated emotions on preventive health behaviour if specified at the level of behavioural outcomes. Consistent with predictions from a recently developed model of goal pursuit, we hypothesized that the impact of emotions on effort levels depended on the perceived proximity to the goal. Participants with weight-loss intentions were randomly selected from an Internet panel and completed questionnaires at three points in time, baseline (T1; N= 725), 2 weeks later at T2 (N= 582) and again 2 months later at T3 (N= 528). Questionnaires assessed anticipated emotions (at T1) and experienced emotions (at T2) towards goal attainment and non-attainment. Goal proximity, goal desirability, and effort levels in striving for weight loss were assessed at both T1 and T2. Current and target weights were reported at all three assessments. In line with predictions, we found that negative anticipated emotions towards goal non-attainment resulted in increased effort but only if people perceived themselves in close proximity to their goal. Effort, in turn, predicted weight loss and goal achievement. The current data bear important practical implications as they identify anticipated emotions as targets of behaviour change interventions aimed to stimulate effort in striving for broad, health-related goals like weight loss. ©2010 The British Psychological Society.

  16. Low incidence of painless thyroiditis in the Philadelphia area

    International Nuclear Information System (INIS)

    Schorr, A.B.; Miller, J.L.; Shtasel, P.; Rose, L.I.

    1986-01-01

    Publications from the midwestern region of the United States have demonstrated an incidence of 14-23% of painless thyroiditis in hyperthyroid individuals. This possibly could represent a local phenomenon, and perhaps is not typical for other areas of the country. The 24 hour radioactive iodine uptakes in 152 consecutive hyperthyroid individuals in the Philadelphia area were evaluated. No patient in the series, with clinical and biochemical evidence of hyperthyroidism, had painless thyroiditis. It is concluded that the incidence of painless thyroiditis is markedly lower in the Philadelphia area than in the Midwest regions of the United States

  17. Treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia.

    Science.gov (United States)

    Milone, Jorge H; Enrico, Alicia

    2009-12-01

    The presence of the Philadelphia chromosome is a poor prognosis factor in acute lymphoblastic leukemia (ALL), in both children and adults. Using molecular techniques of the gen bcr/abl, it is possible to detect the abnormality, in up to the 40% of adult patients. The unsatisfactory results with conventional chemotherapy schemes have determined the intensification of the treatments and the consideration of allogenic bone marrow transplants as the best therapeutic instance. The development of tyrosine kinase inhibitors have become a therapeutic improvement in the treatment of Philadelphia chromosome-positive ALL, being combined with chemotherapy schemes, only in a selected group of patients, even in therapeutic programs that include transplant.

  18. (Dis)empowerment: The Implementation of Corrective Mathematics in Philadelphia Empowerment Schools

    Science.gov (United States)

    Connor, Hannah

    2011-01-01

    The need to improve math education around the country has been well documented, especially in urban school systems like Philadelphia. In Spring 2010, only 56.6% of students in Philadelphia Public schools scored proficient or advanced on the Pennsylvania State Standardized Assessment (PSSA). In Philadelphia Empowerment Schools, the 107 lowest…

  19. The Implementation of CRM at FISC Norfolk Detachment Philadelphia

    Science.gov (United States)

    2003-06-01

    Customer Relationship Management system. [28] If FISC decides to implement a CRM system, the decision will impact the duties of the...distribution is unlimited 12b. DISTRIBUTION CODE 13. ABSTRACT (maximum 200 words) Customer Relations Management ( CRM ) can be defined in many ways. In...Norfolk Philadelphia Mission Statement. 15. NUMBER OF PAGES 91 14. SUBJECT TERMS Customer Relations Management System, CRM ,

  20. GATEWAY Report Brief: SSL Evaluation: Philadelphia International Airport Apron Lighting

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2015-10-30

    Summary of report that documents a trial installation of LED apron lighting that replaced the existing high-pressure sodium luminaires at Philadelphia International Airport. Such high-mast applications remain challenging for LED technology, and the lessons learned from this project may help facility managers and LED product manufacturers better meet those challenges.

  1. Item Response Theory Modeling of the Philadelphia Naming Test

    Science.gov (United States)

    Fergadiotis, Gerasimos; Kellough, Stacey; Hula, William D.

    2015-01-01

    Purpose: In this study, we investigated the fit of the Philadelphia Naming Test (PNT; Roach, Schwartz, Martin, Grewal, & Brecher, 1996) to an item-response-theory measurement model, estimated the precision of the resulting scores and item parameters, and provided a theoretical rationale for the interpretation of PNT overall scores by relating…

  2. Systemwide Implementation of Project-Based Learning: The Philadelphia Approach

    Science.gov (United States)

    Schwalm, Jason; Tylek, Karen Smuck

    2012-01-01

    Citywide implementation of project-based learning highlights the benefits--and the challenges--of promoting exemplary practices across an entire out-of-school time (OST) network. In summer 2009, the City of Philadelphia and its intermediary, the Public Health Management Corporation (PHMC), introduced project-based learning to a network of more…

  3. The Post-Revolutionary Woman Idealized: Philadelphia Media's "Republican Mother."

    Science.gov (United States)

    List, Karen K.

    1989-01-01

    Examines eighteenth-century periodical literature published in Philadelphia to explore the major shift of women's roles in the United States during the period following the American Revolution. Notes that independence remained a male prerogative in periodicals, while women's issues and movements toward self-realization were ignored. (MM)

  4. Faith Partnerships and Public Schools in Philadelphia: Rewards and Perils.

    Science.gov (United States)

    Mundell, Leah

    In 1999, Philadelphia (Pennsylvania) school superintendent David Hornbeck introduced educators and religious leaders to his requirement that each public school in the city develop a relationship with a faith partner, a religious institution that could share facilities and resources with the school. Hornbeck saw religious institutions and schools…

  5. Electricity

    CERN Document Server

    Basford, Leslie

    2013-01-01

    Electricity Made Simple covers the fundamental principles underlying every aspect of electricity. The book discusses current; resistance including its measurement, Kirchhoff's laws, and resistors; electroheat, electromagnetics and electrochemistry; and the motor and generator effects of electromagnetic forces. The text also describes alternating current, circuits and inductors, alternating current circuits, and a.c. generators and motors. Other methods of generating electromagnetic forces are also considered. The book is useful for electrical engineering students.

  6. Career Development Strivings: Assessing Goals and Motivation in Career Decision-Making and Planning

    Science.gov (United States)

    Dik, Bryan J.; Sargent, Adam M.; Steger, Michael F.

    2008-01-01

    This article describes and demonstrates a novel approach to assessing goals and motives among individuals engaged in the career decision-making and planning process. Participants generated five career development strivings, rated each striving along several dimensions (self-efficacy, outcome expectations, sense of calling, spiritual significance,…

  7. 41 CFR 102-79.110 - What Integrated Workplace policy must Federal agencies strive to promote?

    Science.gov (United States)

    2010-07-01

    ... capital costs over a substantial time period; and (i) Support alternative workplace arrangements... Workplace policy must Federal agencies strive to promote? 102-79.110 Section 102-79.110 Public Contracts and... Integrated Workplace § 102-79.110 What Integrated Workplace policy must Federal agencies strive to promote...

  8. Faculty Agency in Striving University Contexts: Mundane yet Powerful Acts of Agency

    Science.gov (United States)

    Gonzales, Leslie D.

    2015-01-01

    Drawing from Archer's critical realist theory of agency, this paper has two specific aims. First, the cultural and structural features of one "striving" institution are outlined. Then, I illustrate how faculty members asserted agency inside their striving university in ways intended to disrupt the structures and cultures that striving…

  9. A culture of striving augments use of working memory? Implications for attention control.

    Science.gov (United States)

    Buszard, Tim; Masters, Rich S W

    2017-01-01

    A culture of striving was notable in the developmental background of many of the elite and super elite athletes in the Hardy et al. Critically, a culture of striving was credited with a positive influence on a range of issues relevant to elite sports performance, including performance under pressure. Of the six athletes who did not reveal a culture of striving, five reported the greatest difficulty performing in high-pressure situations. We suspect that a culture of striving facilitates the development of attention control ability, which subsequently assists performance under pressure. We discuss attention control from the perspective of working memory and hypothesize that a culture of striving trains individuals to maximize their working memory capacity. © 2017 Elsevier B.V. All rights reserved.

  10. Demonstration Assessment of LED Roadway Lighting: Philadelphia, PA

    Energy Technology Data Exchange (ETDEWEB)

    Royer, Michael P.; Tuenge, Jason R.; Poplawski, Michael E.

    2012-09-01

    For this demonstration assessment, 10 different groups of LED luminaires were installed at three sites in Philadelphia, PA. Each of the three sites represented a different set of conditions, most importantly with regard to the incumbent HPS luminaires, which were nominally 100 W, 150 W, and 250 W. The performance of each product was evaluated based on manufacturer data, illuminance calculations, field measurements of illuminance, and the subjective impressions of both regular and expert observers.

  11. Electricity

    International Nuclear Information System (INIS)

    Tombs, F.

    1983-01-01

    The subject is discussed, with particular reference to the electricity industry in the United Kingdom, under the headings; importance and scope of the industry's work; future fuel supplies (estimated indigenous fossil fuels reserves); outlook for UK energy supplies; problems of future generating capacity and fuel mix (energy policy; construction programme; economics and pricing; contribution of nuclear power - thermal and fast reactors; problems of conversion of oil-burning to coal-burning plant). (U.K.)

  12. Discovering the Self in Islam: Self-Striving, Self-Regard, and Self-Neglect

    OpenAIRE

    Nik Ahmad Hisham Ismail, Mustafa Tekke

    2016-01-01

    This study explored some self domains and reviewed them through Islamic perspective, more particularly self-knowledge and faith. It provided an extensive literature on particular concepts of self-striving, self-regard, and self-neglect. To briefly point out, the self has many origins, however deeply noted as such heart, spirit, and psyche in Islam. From these, this study looked at the two known self domains: self-striving, and self-regard. Apart from these concepts, researchers differently ch...

  13. Uncovering Clinical Features of De Novo Philadelphia Positive Myelodysplasia.

    Science.gov (United States)

    Armas, Aristides; Chen, Chen; Mims, Martha; Rivero, Gustavo

    2017-01-01

    Myelodysplastic syndrome (MDS) is cytogenetically heterogeneous and retains variable risk for acute myeloid leukemia transformation. Though not yet fully understood, there is an association between genetic abnormalities and defects in gene expression. The functional role for infrequent cytogenetic alteration remains unclear. An uncommon chromosomic abnormality is the presence of the Philadelphia (Ph) chromosome. Here, we report a patient with Ph+ MDS treated with low dose Dasatinib who achieved hematologic response for 7 months. In addition, we also examined the English literature on all de novo Ph + MDS cases between 1996 and 2015 to gain insight into clinical features and outcome.

  14. Everyday strivings in war veterans with posttraumatic stress disorder: suffering from a hyper-focus on avoidance and emotion regulation.

    Science.gov (United States)

    Kashdan, Todd B; Breen, William E; Julian, Terri

    2010-09-01

    This research investigated whether combat veterans' daily strivings are related to the presence of post-traumatic stress disorder (PTSD) and well-being. Veterans created a list of their most important strivings, which were content-analyzed for emotion regulation and approach or avoidance themes. It was hypothesized that veterans pursuing strivings with themes of emotion regulation or avoidance experience deleterious consequences compared with other veterans. For all veterans, devoting finite time and energy in daily life to regulating emotions was associated with less purpose, meaning, and joy compared with other strivings. Veterans with PTSD endorsed more strivings related to emotion regulation and devoted considerable effort to emotion regulation and avoidance strivings. Yet, these efforts failed to translate into any discernible benefits; veterans without PTSD derived greater joy and meaning from strivings focusing on approac- oriented behavior and themes other than emotion regulation. The presence of PTSD and a high rate of emotion regulation strivings led to the lowest global well-being and daily self-esteem during a 14-day assessment period. The presence of PTSD and a high rate of avoidance strivings also led to lower emotional well-being. Results indicate that strivings devoted to regulating emotions or avoidance efforts influence the mental health of veterans with and without PTSD. Studying personality at different levels of analysis-traits, strivings, and life narratives-allows for a fine-grained understanding of emotional disorders.

  15. Urban sustainable energy development: A case study of the city of Philadelphia

    Science.gov (United States)

    Argyriou, Iraklis

    This study explores the role of cities in sustainable energy development through a governance-informed analysis. Despite the leading position of municipalities in energy sustainability, cities have been mostly conceptualized as sites where energy development is shaped by external policy scales, i.e. the national level. A growing body of research, however, critiques this analytical perspective, and seeks to better understand the type of factors and dynamics that influence energy sustainability within a multi-level policy context for urban energy. Given that particular circumstances are applicable across cities, a context-specific analysis can provide insight regarding how sustainable energy development takes place in urban areas. In applying such an analytical perspective on urban energy sustainability, this study undertakes a qualitative case study analysis for the city of Philadelphia, Pennsylvania, by looking at four key local policy initiatives relevant to building energy efficiency and solar electricity development at the municipal government and city-wide level. The evaluation of the initiatives suggests that renewable electricity use has increased substantially in the city over the last years but the installed capacity of local renewable electricity systems, including solar photovoltaics, is low. On the other hand, although the city has made little progress in meeting its building energy efficiency targets, more comprehensive action is taken in this area. The study finds that the above outcomes have been shaped mainly by four factors. The first is the city government's incremental policy approach aiming to develop a facilitative context for local action. The second is the role that a diverse set of stakeholders have in local sustainable energy development. The third is the constraints that systemic policy barriers create for solar power development. The fourth is the ways through which the relevant multi-level policy environment structures the city

  16. Persistence of chromosomal abnormalities additional to the Philadelphia chromosome after Philadelphia chromosome disappearance during imatinib therapy for chronic myeloid leukemia.

    Science.gov (United States)

    Zaccaria, Alfonso; Valenti, Anna Maria; Donti, Emilio; Gozzetti, Alessandro; Ronconi, Sonia; Spedicato, Francesco

    2007-04-01

    Five Philadelphia chromosome positive (Ph+) chronic myeloid leukemia (CML) patients with additional chromosome abnormalities at diagnosis have been followed during Imatinib therapy. In all, the Ph chromosome disappeared, while the 5 cases, additional abnormalities [dup(1); del(5), +8 (2 patients) and +14] persisted in the subsequent studies, performed over a period of 11 to 49 months, either alone or together with a karyotypically normal cell population. This finding is consistent with a secondary origin of the Ph chromosome in these patients. It is still to early to evaluate the possible prognostic value of these additional abnormalities.

  17. Philadelphia (1993: las claves de un icono cultural

    Directory of Open Access Journals (Sweden)

    José Aijón Oliva

    2008-10-01

    Full Text Available Philadelphia responde a la razón fundamental del cine comercial de los últimos tiempos: darle al público aquello que quiere ver. A medida que van surgiendo los problemas en la sociedad, el cine se interesa por ellos y realiza películas centradas en ese tema. A principios de los años 90 la alarma social ante el virus del SIDA era tan importante que surgieron muchas películas que trataban este tema. Philadelphia es la más popular de todas ellas y la más accesible (y probablemente la de mayor calidad cinematográfica, aunque su planteamiento es bastante engañoso: no es tanto una película sobre el SIDA como del rechazo al colectivo homosexual. No obstante, desmitifica algunos aspectos del SIDA y da algunas respuestas que se pueden considerar pedagógicas.             Un gran director, un reparto muy acertado, un guión (de estructura clásica de categoría, una música muy bien seleccionada y unos juegos de luces y cámara muy cuidados son los ingredientes que convierten a esta película en uno de los iconos de la cultura popular de los 90.

  18. Philadelphia chromosome-positive acute lymphoblastic leukemia in childhood

    Directory of Open Access Journals (Sweden)

    Hong Hoe Koo

    2011-03-01

    Full Text Available In pediatric patients with acute lymphoblastic leukemia (ALL, the Philadelphia chromosome translocation is uncommon, with a frequency of less than 5%. However, it is classified as a high or very high risk, and only 20‒30% of Philadelphia chromosome-positive (Ph+ children with ALL are cured with chemotherapy alone. Allogeneic hematopoietic stem cell transplantation from a closely matched donor cures 60% of patients in first complete remission. Recent data suggest that chemotherapy plus tyrosine kinase inhibitors (TKIs may be the initial treatment of choice for Ph+ ALL in children. However, longer observation is required to determine whether long-term outcome with intensive imatinib and chemotherapy is indeed equivalent to that with allogeneic related or alternative donor hematopoietic stem cell transplantation (HSCT. Reports on the use of second-generation TKIs in children with Ph+ ALL are limited. A few case reports have indicated the feasibility and clinical benefit of using dasatinib as salvage therapy enabling HSCT. However, more extensive data from clinical trials are needed to determine whether the administration of secondgeneration TKIs in children is comparable to that in adults. Because Ph+ ALL is rare in children, the question of whether HSCT could be a dispensable part of their therapy may not be answered for some time. An international multicenter study is needed to answer the question of whether imatinib plus chemotherapy could replace sibling allogeneic HSCT in children with Ph+ ALL.

  19. Urban ecosystem services and decision making for a green Philadelphia

    Science.gov (United States)

    Hogan, Dianna M.; Shapiro, Carl D.; Karp, David N.; Wachter, Susan M.

    2014-01-01

    Traditional approaches to urban development often do not account for, or recognize, the role of ecosystem services and the benefits these services provide to the health and well-being of city residents. Without such accounting, urban ecosystem services are likely to be degraded over time, with negative consequences for the sustainability of cities and the well-being of their residents (Millennium Ecosystem Assessment, 2005; Hirsch, 2008). On May 23, 2013, the Spatial Integration Laboratory for Urban Systems (SILUS), a collaboration between the U.S. Geological Survey (USGS) Science and Decisions Center and the Wharton GIS Lab, convened a one-day symposium—Urban Ecosystem Services and Decision Making: A Green Philadelphia—at the University of Pennsylvania in Philadelphia, Pennsylvania, to examine the role of green infrastructure in the environmental, economic, and social well-being of cities. Cosponsored by the USGS and the Penn Institute for Urban Research (Penn IUR), the symposium brought together policymakers, practitioners, and researchers from a range of disciplines to advance a research agenda on the use of science in public decision making to inform investment in green infrastructure and ecosystem services in urban areas. The city of Philadelphia has recently implemented a program designed to sustain urban ecosystem services and advance the use of green infrastructure. In 2009, the Philadelphia Mayor’s Office of Sustainability launched its Greenworks plan, establishing a citywide sustainability strategy. Major contributions towards its goals are being implemented in coordination with the Philadelphia Water Department (PWD). The Green City, Clean Waters initiative, the city’s nationally recognized stormwater management plan, was signed into action with the U.S. Environmental Protection Agency (EPA) in April 2012. The plan outlines a 25-year strategy to use green infrastructure to protect and improve the city’s watershed. Widespread support for the

  20. 78 FR 75902 - Approval and Promulgation of Air Quality Implementation Plans; Pennsylvania; Philadelphia County...

    Science.gov (United States)

    2013-12-13

    ... to EPA. See NRDC v. EPA, 571 F.3d 1245 (D.C. Cir. 2009). Since the Philadelphia County 2006 SIP... Call constitutes RACT for EGU sources in Philadelphia County. Thus, AMS needs to perform a NO X RACT... 52.2020(d)(1)) continue to represent adequately RACT for the 1997 8-hour ozone NAAQS; or (2) perform...

  1. Can self-verification strivings fully transcend the self-other barrier? Seeking verification of ingroup identities.

    Science.gov (United States)

    Gómez, Angel; Seyle, D Conor; Huici, Carmen; Swann, William B

    2009-12-01

    Recent research has demonstrated self-verification strivings in groups, such that people strive to verify collective identities, which are personal self-views (e.g., "sensitive") associated with group membership (e.g., "women"). Such demonstrations stop short of showing that the desire for self-verification can fully transcend the self-other barrier, as in people working to verify ingroup identities (e.g., "Americans are loud") even when such identities are not self-descriptive ("I am quiet and unassuming"). Five studies focus on such ingroup verification strivings. Results indicate that people prefer to interact with individuals who verify their ingroup identities over those who enhance these identities (Experiments 1-5). Strivings for ingroup identity verification were independent of the extent to which the identities were self-descriptive but were stronger among participants who were highly invested in their ingroup identities, as reflected in high certainty of these identities (Experiments 1-4) and high identification with the group (Experiments 1-5). In addition, whereas past demonstrations of self-verification strivings have been limited to efforts to verify the content of identities (Experiments 1 to 3), the findings also show that they strive to verify the valence of their identities (i.e., the extent to which the identities are valued; Experiments 4 and 5). Self-verification strivings, rather than self-enhancement strivings, appeared to motivate participants' strivings for ingroup identity verification. Links to collective self-verification strivings and social identity theory are discussed.

  2. Seasonal dependence of aerosol processing in urban Philadelphia

    Science.gov (United States)

    Avery, A. M.; Waring, M. S.; DeCarlo, P. F.

    2017-12-01

    Urban aerosols pose an important threat to human health due to the conflation of emissions and concentrated population exposed. Winter and summer aerosol and trace gas measurements were taken in downtown Philadelphia in 2016. Measurements included aerosol composition and size with an Aerodyne Aerosol Mass Spectrometer (AMS), particle size distributions with an SMPS, and an aethalometer. Trace gas measurements of O3, NO, CH4, CO, and CO2 were taken concurrently. Sampling in seasonal extremes provided contrast in aerosol and trace gas composition, aerosol processing, and emission factors. Inorganic aerosol components contributed approximately 60% of the submicron aerosol mass, while summertime aerosol composition was roughly 70% organic matter. Positive Matrix Factorization (PMF) on the organic aerosol (OA) matrix revealed three factors in common in each season, including an oxygenated organic aerosol (OOA) factor with different temporal behavior in each season. In summertime, OOA varied diurnally with ozone and daytime temperature, but in the wintertime, it was anti-correlated with ozone and temperature, and instead trended with calculated liquid water, indicating a seasonally-dependent processing of organic aerosol in Philadelphia's urban environment. Due to the inorganic dominant winter aerosol, liquid water much higher (2.65 μg/m3) in winter than in summer (1.54 μg/m3). Diurnally varying concentrations of background gas phase species (CH4, CO2) were higher in winter and varied less as a result of boundary layer conditions; ozone was also higher in background in winter than summer. Winter stagnation events with low windspeed showed large buildup of trace gases CH4, CO, CO2, and NO. Traffic related aerosol was also elevated with black carbon and hydrocarbon-like OA (HOA) plumes of each at 3-5 times higher than the winter the average value for each. Winter ratios of HOA to black carbon were significantly higher in the winter than the summer due to lower

  3. Learning From Philadelphia: Topographies of HIV/AIDS Media Assemblages.

    Science.gov (United States)

    Cartwright, Lisa

    2016-01-01

    For this contribution to the special issue on "Mapping Queer Bioethics," the author employs an array of public health and popular media texts (especially Jonathan Demme's film Philadelphia) to challenge the construction and reconstruction of HIV-positive bodies as sites of bioethical concern. In outlining notions of "digital restoration," the author argues that there has been of late a remapping of the first decade of the HIV/AIDS pandemic through media projects assembled from archived materials. Accordingly, the author suggests that in the first decades of the 2000s, we have witnessed a media-archaeological turn, whereby old materials have been reassembled for commemorative purposes that oftentimes perform a reshaping of the topography of the first decade of the AIDS pandemic.

  4. Volunteer Environmental Stewardship and Affective Labour in Philadelphia

    Directory of Open Access Journals (Sweden)

    Alec Foster

    2018-01-01

    Full Text Available Recent research has critically evaluated the rapid growth of volunteer urban environmental stewardship. Framings of this phenomenon have largely focused upon environmentality and/or neoliberal environments, unfortunately often presenting a totalising picture of the state and/or market utilising power from above to create environmental subjects with limited agency available to local citizens. Based upon qualitative research with volunteer urban environmental stewards in Philadelphia, affective labour is proposed as an alternative explanation for participation. Stewards volunteered their time and labour due to the intense emotional attachments they formed with their neighbourhoods, neighbours, and nonhuman others in relationships of affective labour. Volunteer urban environmental stewardship as affective labour provides room for agency on the part of individuals and groups involved in volunteer urban environmental reproduction and opens up new ways of relating to and being with human and nonhuman others.

  5. Exploring Faculty Experiences in a Striving University through the Lens of Academic Capitalism

    Science.gov (United States)

    Gonzales, Leslie D.; Martinez, E.; Ordu, C.

    2014-01-01

    In this paper, we draw from academic capitalism to explore the work lives and experiences of faculty who work in a striving university. Our analysis suggests that faculty members feel pressures induced by academic capitalism, including a lack of space, no time and the sense of constant surveillance. Our work adds to the theoretical as well as…

  6. Effects of Goal-Striving Stress on the Mental Health of Black Americans

    Science.gov (United States)

    Sellers, Sherrill L.; Neighbors, Harold W.

    2008-01-01

    Although many scholars have theorized about how responding to the stress of blocked opportunities can affect the well-being of black Americans, few scholars have empirically examined the relationships between striving efforts, personal goals, and mental health among black Americans. This investigation examines the relationship between…

  7. Striving for habitual well-being in non-invasive ventilation

    DEFF Research Database (Denmark)

    Sørensen, Dorthe; Frederiksen, Kirsten; Grøfte, Thorbjørn

    2013-01-01

    December 2009 to January 2012. Results. A substantive theory of striving for habitual well-being was developed. The theory included three phases: initiation, transition, and determination. Each phase contained a set of subcategories to indicate the dimensions of and variations in the participants...

  8. Women Faculty Departures from a Striving Institution: Between a Rock and a Hard Place

    Science.gov (United States)

    Gardner, Susan K.

    2013-01-01

    The quest for institutional prestige in the academic hierarchy has become a common phenomenon among universities in the United States. At the same time, the institutions that choose to embark on such a journey (referred to as striving institutions) have not been closely examined to determine how such efforts influence the different constituencies…

  9. Microgrid Controller Design, Implementation, and Deployment: A Journey from Conception to Implementation at the Philadelphia Navy Yard

    Energy Technology Data Exchange (ETDEWEB)

    Uluski, R.; Kumar, J.; Venkata, S. S. Mani; Vishwakarma, D.; Schneider, K.; Mehrizi-Sani, Ali; Terry, Rudy; Agate, Will

    2017-07-01

    The Philadelphia Navy Yard is a fast-evolving community microgrid, currently home to over 150 companies and four Navy activity centers occupying nearly 7 million ft2 of buildings in which approximately 12,000 people are employed. The Navy Yard (TNY) is a national center of excellence for energy research, education, and commercialization, focused specifically on community microgrid design and development. TNY microgrid is equipped with the most cost-effective and sustainable means for meeting electric capacity and energy needs through renewable resources, energy efficiency, and distribution grid infrastructure. This article briefly describes how the community microgrid was conceived and planned to produce a great success story of microgrid implementation and the details of the design, development, and implementation of the TNY microgrid controller.

  10. Assessment of Child Lead Exposure in a Philadelphia Community, 2014.

    Science.gov (United States)

    Dignam, Timothy; Pomales, Ana; Werner, Lora; Newbern, E Claire; Hodge, James; Nielsen, Jay; Grober, Aaron; Scruton, Karen; Young, Rand; Kelly, Jack; Brown, Mary Jean

    2018-01-10

    Several urban neighborhoods in Philadelphia, Pennsylvania, have a history of soil, household lead paint, and potential lead-emitting industry contamination. To (1) describe blood lead levels (BLLs) in target neighborhoods, (2) identify risk factors and sources of lead exposure, (3) describe household environmental lead levels, and (4) compare results with existing data. A simple, random, cross-sectional sampling strategy was used to enroll children 8 years or younger living in selected Philadelphia neighborhoods with a history of lead-emitting industry during July 2014. Geometric mean of child BLLs and prevalence of BLLs of 5 μg/dL or more were calculated. Linear and logistic regression analyses were used to ascertain risk factors for elevated BLLs. Among 104 children tested for blood lead, 13 (12.4%; 95% confidence interval [CI], 7.5-20.2) had BLLs of 5 μg/dL or more. The geometric mean BLL was 2.0 μg/dL (95% CI, 1.7-2.3 μg/dL). Higher geometric mean BLLs were significantly associated with front door entryway dust lead content, residence built prior to 1900, and a child currently or ever receiving Medicaid. Seventy-one percent of households exceeded the screening level for soil, 25% had an elevated front door floor dust lead level, 28% had an elevated child play area floor dust lead level, and 14% had an elevated interior window dust lead level. Children in households with 2 to 3 elevated environmental lead samples were more likely to have BLLs of 5 μg/dL or more. A spatial relationship between household proximity to historic lead-emitting facilities and child BLL was not identified. Entryway floor dust lead levels were strongly associated with blood lead levels in participants. Results underscore the importance to make housing lead safe by addressing all lead hazards in and around the home. Reduction of child lead exposure is crucial, and continued blood lead surveillance, testing, and inspection of homes of children with BLLs of 5 μg/dL or more to identify

  11. 41 CFR 102-193.25 - What type of records management business process improvements should my agency strive to achieve?

    Science.gov (United States)

    2010-07-01

    ... management business process improvements should my agency strive to achieve? 102-193.25 Section 102-193.25...-193.25 What type of records management business process improvements should my agency strive to... correspondence; (b) Design forms that are easy to fill-in, read, transmit, process, and retrieve, and reduce...

  12. 78 FR 14359 - Verizon Business Networks Services, Inc., Specialist-Tech Customer Service, Philadelphia, PA...

    Science.gov (United States)

    2013-03-05

    ... Business Networks Services, Inc., Specialist-Tech Customer Service, Philadelphia, PA; Verizon Business Networks Services, Inc., Specialist-Tech Customer Service, Tampa, Florida; Amended Certification Regarding... should [[Page 14360

  13. Settlement to Improve Water Quality in Delaware River, Philadelphia-Area Creeks

    Science.gov (United States)

    EPA and the U.S. Department of Justice have reached agreement with a major water utility in the greater Philadelphia area to significantly reduce sewage discharges to the Delaware River and local creeks.

  14. Relationship Between Total and Biaccessible Lead on Children's Blood Lead Levles in Urban Residential Philadelphia Soils.

    Data.gov (United States)

    U.S. Environmental Protection Agency — Relationship Between Total and Biaccessible Lead on Children's Blood Lead Levles in Urban Residential Philadelphia Soils. This dataset is not publicly accessible...

  15. SEASONAL ABUNDANCE OF ORGANIC MOLECULAR MARKERS IN URBAN PARTICULATE MATTER FROM PHILADELPHIA, PA

    Science.gov (United States)

    Organic molecular markers were measured in airborne particulate matter (PM10) from the City of Philadelphia North Broad Street air quality monitoring site to identify the seasonal abundances of key tracer compounds together with their dominant sources. Daily PM10...

  16. Increased gene expression of histone deacetylases in patients with Philadelphia-negative chronic myeloproliferative neoplasms

    DEFF Research Database (Denmark)

    Skov, Vibe; Larsen, Thomas Stauffer; Thomassen, Mads

    2012-01-01

    Abstract Myeloproliferation, myeloaccumulation (decreased apoptosis), inflammation, bone marrow fibrosis and angiogenesis are cardinal features of the Philadelphia-negative chronic myeloproliferative neoplasms: essential thrombocythemia (ET), polycythemia vera (PV) and primary myelofibrosis (PMF...

  17. Philadelphia chromosome-negative myeloproliferative disorders: biology and treatment.

    Science.gov (United States)

    Hoffman, Ronald; Prchal, Josef T; Samuelson, Scott; Ciurea, Stefan O; Rondelli, Damiano

    2007-01-01

    The Philadelphia chromosome (Ph)-negative myeloproliferative disorders (MPDs) include essential thrombocythemia (ET), idiopathic myelofibrosis (IMF), and polycythemia vera (PV). All of these disorders are clonal hematologic malignancies originating at the level of the pluripotent hematopoietic stem cell. Recently, activating mutations of the intracellular cytokine-signaling molecule JAK2 have been identified in > 90% of patients with PV and in 50% of those with IMF and ET. In addition, a mutation of the thrombopoietin receptor, MPLW515L, has been documented in some patients with IMF. Both mutations activate JAK-STAT signaling pathways and likely play a role in disease progression. Both ET and PV are associated with prolonged clinical courses associated with frequent thrombotic and hemorrhagic events, and progression to myelofibrosis and acute leukemia. IMF has a much poorer prognosis and is associated with cytopenias, splenomegaly, extramedullary hematopoiesis, and bone marrow fibrosis. Stratification of risk for the development of complications from Ph-negative MPDs has guided the identification of appropriate therapies for this population. Intermediate/high-risk IMF or myelofibrosis after ET or PV is associated with a sufficiently poor prognosis to justify the use of allogeneic stem cell transplantation, which is capable of curing such patients. Reduced-intensity conditioning in preparation for allogeneic stem cell transplantation has permitted older patients with IMF to undergo transplantation with increasing success.

  18. Defensible Spaces in Philadelphia: Exploring Neighborhood Boundaries Through Spatial Analysis

    Directory of Open Access Journals (Sweden)

    Rory Kramer

    2017-02-01

    Full Text Available Few spatial scales are as important to individual outcomes as the neighborhood. However, it is nearly impossible to define neighborhoods in a generalizable way. This article proposes that by shifting the focus to measuring neighborhood boundaries rather than neighborhoods, scholars can avoid the problem of the indefinable neighborhood and better approach questions of what predicts racial segregation across areas. By quantifying an externality space theory of neighborhood boundaries, this article introduces a novel form of spatial analysis to test where potential physical markers of neighborhood boundaries (major roads, rivers, railroads, and the like are associated with persistent racial boundaries between 1990 and 2010. Using Philadelphia as a case study, the paper identifies neighborhoods with persistent racial boundaries. It theorizes that local histories of white reactions to black in-migration explain which boundaries persistently resisted racial turnover, unlike the majority of Philadelphia’s neighborhoods, and that those racial boundaries shape the location, progress, and reaction to new residential development in those neighborhoods.

  19. Ethical and cultural striving: Lived experiences of minority nurses in dementia care.

    Science.gov (United States)

    Egede-Nissen, Veslemøy; Sellevold, Gerd Sylvi; Jakobsen, Rita; Sørlie, Venke

    2017-09-01

    Nursing workforce in Western European health institutions has become more diverse because of immigration and recruitment from Asian, African, and East-European countries. Minority healthcare providers may experience communication problems in interaction with patients and coworkers, and they are likely to experience conflict or uncertainty when confronted with different cultural traditions and values. Persons with dementia are a vulnerable group, and the consequences of their illness challenge the ability to understand and express oneself verbally. The large number of minority healthcare providers in nursing homes underlines the importance to obtain better knowledge about this group's experiences with the care challenges in dementia care units. Can you tell about any challenges in the experiences in the encounter with persons suffering from dementia? Participants and research context: Five minority healthcare providers in a nursing home, in a dementia unit. All guidelines for research ethic were followed. Ethical consideration: The participants were informed that participation was voluntary, and they were guarantied anonymity. We used a qualitative method, conducting individual interviews, using a narrative approach. In the analysis, we applied a phenomenological-hermeneutical method, developed for researching life experiences. One theme and four subthemes: striving to understand the quality of care for persons with dementia. The subthemes: sensitivity to understand the patients' verbal and nonverbal expressions. To understand gratefulness, understand the patient as an adult and autonomous person, and understand the patient as a patient in a nursing home. Challenges comprise both ethical and cultural striving to understand persons with dementia. To care for persons with dementia in an unfamiliar context may be understood as a striving for acting ethically, when at the same time striving to adapt and acculturate to new cultural norms, in order to practice good

  20. Nurses negotiating professional-familial care boundaries: striving for balance within double duty caregiving.

    Science.gov (United States)

    Ward-Griffin, Catherine; Brown, Judith Belle; St-Amant, Oona; Sutherland, Nisha; Martin-Matthews, Anne; Keefe, Janice; Kerr, Mickey

    2015-02-01

    The purpose of this sequential, two-phase mixed-methods study was to examine the health of male and female nurses who provided care to older relatives (i.e., double duty caregivers). We explored the experiences of 32 double duty caregivers, which led to the development of an emergent grounded theory, Negotiating Professional-Familial Care Boundaries with two broad dialectical processes: professionalizing familial care and striving for balance. This article examines striving for balance, which is the process that responds to familial care expectations in the midst of available resources and reflects the health experiences of double duty caregivers. Two subprocesses of striving for balance, reaping the benefits and taking a toll, are presented in three composite vignettes, each representing specific double duty caregiving (DDC) prototypes (making it work, working to manage, living on the edge). This emergent theory extends current thinking of family caregiving that will inform the development and refinement of practices and policies relevant to DDC. © The Author(s) 2014.

  1. Striving for meaning-Life in supported housing for people with psychiatric disabilities.

    Science.gov (United States)

    Brolin, Rosita; Brunt, David; Rask, Mikael; Syrén, Susanne; Sandgren, Anna

    2016-01-01

    The aim of this study was to develop a grounded theory about people with psychiatric disabilities, living in supported housing. Interviews as well as observations during the interviews were analyzed together with secondary analyses of quantitative and qualitative material from previous studies. Being deprived of self-determination emerged as the main concern for residents in supported housing and striving for meaning emerged as the pattern of behavior through which this group resolves their main concern. Striving for meaning involves living in the present, striving for self-determination, strengthening self-esteem, emotional processing and resting from the present. The strategies facilitate each other and are used singly, together simultaneously, or alternately. If they are successful, a meaning in the present is perceived. If all the strategies fail repeatedly, escaping from the present is used in order to deal with being deprived of self-determination. The implications of the findings suggest prioritizing a reduction of the institutional nature of the social and physical environment, and to support the residents' self-determination.

  2. Measuring striving for understanding and learning value of geometry: a validity study

    Science.gov (United States)

    Ubuz, Behiye; Aydınyer, Yurdagül

    2017-11-01

    The current study aimed to construct a questionnaire that measures students' personality traits related to striving for understanding and learning value of geometry and then examine its psychometric properties. Through the use of multiple methods on two independent samples of 402 and 521 middle school students, two studies were performed to address this issue to provide support for its validity. In Study 1, exploratory factor analysis indicated the two-factor model. In Study 2, confirmatory factor analysis indicated the better fit of two-factor model compared to one or three-factor model. Convergent and discriminant validity evidence provided insight into the distinctiveness of the two factors. Subgroup validity evidence revealed gender differences for striving for understanding geometry trait favouring girls and grade level differences for learning value of geometry trait favouring the sixth- and seventh-grade students. Predictive validity evidence demonstrated that the striving for understanding geometry trait but not learning value of geometry trait was significantly correlated with prior mathematics achievement. In both studies, each factor and the entire questionnaire showed satisfactory reliability. In conclusion, the questionnaire was psychometrically sound.

  3. Striving for meaning—Life in supported housing for people with psychiatric disabilities

    Directory of Open Access Journals (Sweden)

    Rosita Brolin

    2016-05-01

    Full Text Available The aim of this study was to develop a grounded theory about people with psychiatric disabilities, living in supported housing. Interviews as well as observations during the interviews were analyzed together with secondary analyses of quantitative and qualitative material from previous studies. Being deprived of self-determination emerged as the main concern for residents in supported housing and striving for meaning emerged as the pattern of behavior through which this group resolves their main concern. Striving for meaning involves living in the present, striving for self-determination, strengthening self-esteem, emotional processing and resting from the present. The strategies facilitate each other and are used singly, together simultaneously, or alternately. If they are successful, a meaning in the present is perceived. If all the strategies fail repeatedly, escaping from the present is used in order to deal with being deprived of self-determination. The implications of the findings suggest prioritizing a reduction of the institutional nature of the social and physical environment, and to support the residents’ self-determination.

  4. Striving for balance between family and work demands among Iranian nurses.

    Science.gov (United States)

    Lagerström, Monica; Josephson, Malin; Arsalani, Narges; Fallahi-Khoshknab, Masoud

    2010-04-01

    The study reported here explored Iranian nurses' experience of managing work and family roles. Grounded theory method guided the data collection and data analysis from both individual and focus group interviews. Five categories emerged: family role, working conditions, seeking support, perceiving dissatisfaction, and perceiving threats to health. The core concept that emerged was striving for balance between family and work demands. In the work-family role the Iranian nurses faced significant pressures, and they mostly relied on their own capabilities to create balance, often neglecting their own needs. This resulted in perceived dissatisfaction and health threats.

  5. Does striving to succeed come at a physiological or psychosocial cost for adults who experienced child maltreatment?

    Science.gov (United States)

    Doom, Jenalee R; Hazzard, Vivienne M; Bauer, Katherine W; Clark, Cari Jo; Miller, Alison L

    2017-12-01

    While striving to succeed in the face of adversity may provide individuals with outward benefits, it may come at a cost to individuals' physical health. The current study examines whether striving predicts greater physiological or psychosocial costs among those who experienced child maltreatment, a stressor that disrupts the caregiving environment and threatens relationship security. Using data from the National Longitudinal Study of Adolescent to Adult Health, we tested whether greater striving after childhood maltreatment would come at a cost, increasing underlying cardiovascular disease (CVD) risk and depressive symptoms despite showing outward success via income and college degree attainment. The study included 13,341 Black, Hispanic, and White adolescents who self-reported striving and their experiences of childhood neglect, physical abuse, and sexual abuse. As young adults, participants reported depressive symptoms, income, and college degree attainment and completed a health assessment from which a 30-year Framingham-based CVD risk score was calculated. Higher striving was associated with lower CVD risk and depressive symptoms, and higher income and college degree attainment, regardless of maltreatment history. These findings highlight the potential for striving as a target for interventions and support the need to examine multiple biological and behavioral outcomes to understand the multifaceted nature of resilience.

  6. Philadelphia obtains useful information from its customers about taste and odour quality.

    Science.gov (United States)

    Burlingame, G A; Mackey, E D

    2007-01-01

    Customers are sensitive to the flavour of water. Customers evaluate drinking water based on their expectations, on experiences with their usual drinking water and on experiences with alternative waters. The Philadelphia Water Department provides one example of success in developing a better understanding of customer perceptions and attitudes about tap water taste and odour. Philadelphia found that customers do communicate in ways that water utilities can understand. Water utilities can enhance that communication and collect useful data. In addition, water utilities can characterise their tap water flavour, track it for changes and correlate changes to customer complaints.

  7. Hospitality and Inclusion Logistics of a Spotlight Event: An Insiders Look at the 2016 DNC in Philadelphia

    Directory of Open Access Journals (Sweden)

    Leora Halpern Lanz

    2016-10-01

    Full Text Available The 2016 Democratic National Convention held in Philadelphia, Pennsylvania prioritized hospitality efforts and incorporated inclusion and diversity as its theme. These strategies helped to create a successful spotlight event, benefiting the city of Philadelphia and its hospitality industry.

  8. GATEWAY Demonstrations: Philadelphia International Airport Apron Lighting: LED System Performance in a Trial Installation

    Energy Technology Data Exchange (ETDEWEB)

    Davis, Robert G. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Wilkerson, Andrea M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-10-30

    This report documents a trial installation of LED apron lighting that replaced the existing high-pressure sodium luminaires at Philadelphia International Airport. Such high-mast applications remain challenging for LED technology, and the lessons learned from this project may help facility managers and LED product manufacturers better meet those challenges.

  9. Assessing Vulnerability to Heat: A Geospatial Analysis for the City of Philadelphia

    Directory of Open Access Journals (Sweden)

    Laura Barron

    2018-04-01

    Full Text Available Urban heat island (UHI effect is an increasingly prominent health and environmental hazard that is linked to urbanization and climate change. Greening reduces the negative impacts of UHI; trees specifically are the most effective in ambient temperature reduction. This paper investigates vulnerability to heat in the Philadelphia, Pennsylvania and identifies where street trees can be planted as a public intervention. We used geospatial information systems (GIS software to map a validated Heat Vulnerability Index to identify vulnerability at the block level. Using a high-low geospatial cluster analysis, we assessed where the City of Philadelphia can most effectively plant street trees to address UHI. This information was then aggregated to the neighborhood level for more effective citizen communication and policymaking. We identified that 26 of 48 (54% neighborhoods that were vulnerable to heat also lacked street trees. Of 158 Philadelphia neighborhoods, 63 (40% contained block groups of high vulnerability to either heat or street tree infrastructure. Neighborhoods that were ranked highest in both classifications were identified in two adjacent West Philadelphia neighborhoods. Planting street trees is a public service a city can potentially reduce the negative health impacts of UHI. GIS can be used to identify and recommend street tree plantings to reduce urban heat.

  10. 78 FR 76779 - Proposed Modification of the Philadelphia, PA, Class B Airspace Area

    Science.gov (United States)

    2013-12-19

    ... regulatory and informational requirements to the scale of the businesses, organizations, and governmental... businesses, not-for-profit organizations, and small governmental jurisdictions. Agencies must perform a... southeast than intended from the Philadelphia International Airport. This was caused by the miscalculation...

  11. Heterogeneity of genomic fusion of BCR and ABL in Philadelphia chromosome-positive acute lymphoblastic leukemia

    International Nuclear Information System (INIS)

    Rubin, C.M.; Carrino, J.J.; Dickler, M.N.; Leibowitz, D.; Smith, S.D.; Westbrook, C.A.

    1988-01-01

    Philadelphia chromosome-positive acute lymphoblastic leukemia occurs in two molecular forms, those with and those without rearrangement of the breakpoint cluster region on chromosome 22. The molecular abnormality in the former group is similar to that found in chronic myelogenous leukemia. To characterize the abnormality in the breakpoint cluster region-unrearranged form, the authors have mapped a 9; 22 translocation from the Philadelphia chromosome-positive acute lymphoblastic leukemia cell line SUP-B13 by using pulsed-field gel electrophoresis and have cloned the DNA at the translocation junctions. They demonstrate a BCR-ABL fusion gene on the Philadelphia chromosome. The exons from ABL are the same. Analysis of leukemic cells from four other patients with breakpoint cluster region-unrearranged Philadelphia chromosome-positive acute lymphoblastic leukemia revealed a rearrangement on chromosome 22 close to the breakpoint in SUP-B13 in only one patient. These data indicate that breakpoints do not cluster tightly in this region but are scattered, possibly in a large intron. Given the large size of BCR and the heterogeneity in breakpoint location, detection of BCR rearrangement by standard Southern blot analysis is difficult. Pulsed-field gel electrophoresis should allow detection at the DNA level in every patient and thus will permit clinical correlation of the breakpoint location with prognosis

  12. A Survey of Automotive Mechanics Programs in the Philadelphia Public Schools. Report No. 8701.

    Science.gov (United States)

    Chern, Hermine J.; And Others

    During March and April of 1986, the three members of the Career Education Evaluation Unit of the Philadelphia (Pennsylvania) School District interviewed 29 automotive mechanics teachers working at nine comprehensive high schools, two vocational technical schools, and two skills centers. The interviews focused on the implementation of standardized…

  13. 75 FR 25010 - Self-Regulatory Organizations; Stock Clearing Corporation of Philadelphia; Notice of Filing and...

    Science.gov (United States)

    2010-05-06

    ...-025, The NASDAQ Stock Market LLC (``NASDAQ Exchange'') sought and received Commission approval to... requirements apply to elections of directors and were not amended. Each share of common stock has one vote,\\8...-Regulatory Organizations; Stock Clearing Corporation of Philadelphia; Notice of Filing and Immediate...

  14. 78 FR 39601 - Safety Zone, Sugar House Casino Fireworks Display, Delaware River; Philadelphia, PA

    Science.gov (United States)

    2013-07-02

    ...-AA00 Safety Zone, Sugar House Casino Fireworks Display, Delaware River; Philadelphia, PA AGENCY: Coast... the Delaware River. Sugar House Casino has contracted with Pyrotecnico Fireworks to arrange for this display. The Captain of the Port, Sector Delaware Bay, has determined that the Sugar House Casino...

  15. Elements of Success: WorkReady Philadelphia Program Year 2011-2012 Report

    Science.gov (United States)

    Philadelphia Youth Network, 2012

    2012-01-01

    What does it take to deliver WorkReady Philadelphia's high-quality career-connected programming? In short, it's all about the "elements"--those essential components of the system that combine to produce success for young people. This 2011-12 WorkReady report reinforces this theme by using visual aspects of the "Periodic Table of…

  16. Interferon-alpha in the treatment of Philadelphia-negative chronic myeloproliferative neoplasms. Status and perspectives

    DEFF Research Database (Denmark)

    Hasselbalch, Hans Carl; Larsen, Thomas Stauffer; Riley, Caroline Hasselbalch

    2011-01-01

    The Philadelphia-negative chronic myeloproliferative neoplasms encompass essential thrombocythemia (ET), polycythemia vera (PV) and primary myelofibrosis (PMF). A major break-through in the understanding of the pathogenesis of these neoplasms occurred in 2005 by the discovery of the JAK2 V617F...

  17. Unfulfilled Promise: The Dimensions and Characteristics of Philadelphia's Dropout Crisis, 2000-2005

    Science.gov (United States)

    Neild, Ruth Curran; Balfanz, Robert

    2006-01-01

    This report uses a unique set of data obtained from the Kids Integrated Data System (KIDS), which is housed at the University of Pennsylvania's Cartographic Modeling Laboratory. The KIDS system merges individual-level data on young people from the School District of Philadelphia and the city's social service agencies, including the Department of…

  18. Educating English Language Learners: Instructional Approaches and Teacher Collaboration in Philadelphia Public Schools. PERC Research Brief

    Science.gov (United States)

    Reumann-Moore, Rebecca; Rowland, Jeannette; Hughes, Rosemary; Lin, Joshua

    2016-01-01

    Districts, charter management organizations, and individual schools can learn a great deal from each other about strategies for creating robust and supportive learning environments for English Language Learners (ELLS). This brief highlights key findings about how Philadelphia public schools were crafting instructional approaches to serve their…

  19. Contracting Out Schools: The First Year of the Philadelphia Diverse Provider Model

    Science.gov (United States)

    Bulkley, Katrina; Mundell, Leah; Riffer, Morgan

    2004-01-01

    Educators nationwide focused on Philadelphia in the summer of 2001 as politicians and policy makers explored the possibility of a state takeover of the city's school system, a seismic power shift that would produce the largest privatization of a public school district in American history. The findings reported in this document are based on…

  20. Philadelphia's community based drug abuse program: broader medical and social concepts.

    Science.gov (United States)

    Schut, J

    1975-06-01

    The rehabilitation of drug dependent people has undergone drastic changes since first attempts were made to curb the abuse of illegal drugs. The isolated law-enforcement model proved to be of no use in this area. So, too, the medical model, the psychological model and the public health model proved disappointingly low in their results. During the last ten years, a so-called "metabolic replacement model" has had its upsurge, creating a controversy still under discussion. The Drug Abuse Rehabilitation Programs of the West Philadelphia Community Mental Health Consortium, Inc. have been in the forefront with its treatment models. Established in 1968 as a purely methadone maintenance program, it has evolved into becoming a model, applying community mental health principles. This paper will explore this model further, describing the mechanics of its changes. From a municipal hospital-based methadone dispensing station, the program has developed into a multi-modality project. Three decentralized drug-free outpatient services are located in the midst of the community where the drug abuse problem is more accute. Outreach is emphasized and case-funding is applied. A possibly unique river-front motel was just acquired for the development of a community-based treatment modality. The 94 rooms were converted into a first-floor alcoholism program which also has a "highway safety program" and an intermediate care facility for alcoholics. The second floor of this facility contains outpatient services for the treatment of drug addicts, including a methadone maintenance program, counselling, family therapy and group therapy. The place where most of the emphasis has been placed is the Work Rehabilitation Center (a novel approach whereby patients will spend up to six hours in "partial hospitalization"). Clients will be tested for vocational aptitude and four workshops will be developed on the premises - carpentry, automotive, electricity and clerical. A huge cafeteria with a semi

  1. Electric Energy Access in Bangladesh

    Directory of Open Access Journals (Sweden)

    Muhammad Taheruzzaman

    2016-07-01

    Full Text Available This paper represents the overall electrical energy profile and access in Bangladesh. In the recent past Bangladesh has been experiencing shortage of electricity, and about 42 % of population no access to the electricity. The electricity consumption has rapidly increased over last decade. The demand and consumption will intensify in the remote future as overall development and future growth. To set “vision 2021” of Bangladesh; government of Bangladesh has devoted to ensuring access of affordable and reliable electricity for all by 2021. In the modern time, energy is the vital ingredient for socioeconomic growth in the developing country i.e., alleviating poverty. Along with electricity access in Bangladesh strived to become middle income country by 2021. Bangladesh has experienced that energy consumption inclines to increase rapidly when per capita income researches between US$ 1,000 and US$ 10,000, and a country’s

  2. Acute, fatal Sarcocystis calchasi-associated hepatitis in Roller pigeons (Columbia livia f. dom.) at Philadelphia Zoo

    Science.gov (United States)

    Four Roller pigeons (Columba livia f. dom.) at the Philadelphia Zoo died suddenly. Necropsy examination revealed macroscopic hepatitis. Microscopically, the predominant lesions were in liver, characterized with necrosis and mixed cell inflammatory response. Sarcocystis calchasi-like schizonts and fr...

  3. Relationship Between Total and Bioaccessible Lead on Children’s Blood Lead Levels in Urban Residential Philadelphia Soils

    Science.gov (United States)

    Relationships between total soil or bioaccessible lead (Pb), measured using an in vitro bioaccessibility assay, and children’s blood lead levels (BLL) were investigated in an urban neighborhood in Philadelphia, Pennsylvania, USA, with a history of soil Pb contamination....

  4. Buying Program of the Standard Automated Materiel Management System. Automated Small Purchase System: Defense Supply Center Philadelphia

    National Research Council Canada - National Science Library

    2001-01-01

    The Standard Automated Materiel Management System Automated Small Purchase System is a fully automated micro-purchases system used by the General and Industrial Directorate at the Defense Supply Center Philadelphia...

  5. Pediatric radiology in the Philadelphia region: a history of pedigrees and legacies

    International Nuclear Information System (INIS)

    Markowitz, Richard I.

    2009-01-01

    The specialty of pediatric radiology in the Philadelphia region has grown and evolved over the past eight decades originating from early ''visiting'' radiologists to Drs. Hope and Kirkpatrick, the ''giants'' of the 1950s and 1960s, to over 40 actively practicing pediatric radiologists. Clinical excellence, commitment to teaching, and advancement of knowledge through research remain the goals and ideals, much as they were many years ago. Philadelphia has been a fertile home and environment for this development, mostly because of outstanding leaders and role models who have trained and influenced generations of pediatric radiologists. The purpose of this article is to tell the story of this growth and development and to explore the intellectual origins, professional ''genealogy,'' and legacies left by those who created this tradition. (orig.)

  6. Pediatric radiology in the Philadelphia region: a history of pedigrees and legacies

    Energy Technology Data Exchange (ETDEWEB)

    Markowitz, Richard I. [University of Pennsylvania School of Medicine, Department of Radiology, Children' s Hospital of Philadelphia, Philadelphia, PA (United States); Children' s Hospital of Philadelphia, Department of Radiology, Philadelphia, PA (United States)

    2009-09-15

    The specialty of pediatric radiology in the Philadelphia region has grown and evolved over the past eight decades originating from early ''visiting'' radiologists to Drs. Hope and Kirkpatrick, the ''giants'' of the 1950s and 1960s, to over 40 actively practicing pediatric radiologists. Clinical excellence, commitment to teaching, and advancement of knowledge through research remain the goals and ideals, much as they were many years ago. Philadelphia has been a fertile home and environment for this development, mostly because of outstanding leaders and role models who have trained and influenced generations of pediatric radiologists. The purpose of this article is to tell the story of this growth and development and to explore the intellectual origins, professional ''genealogy,'' and legacies left by those who created this tradition. (orig.)

  7. Pediatric radiology in the Philadelphia region: a history of pedigrees and legacies.

    Science.gov (United States)

    Markowitz, Richard I

    2009-09-01

    The specialty of pediatric radiology in the Philadelphia region has grown and evolved over the past eight decades originating from early "visiting" radiologists to Drs. Hope and Kirkpatrick, the "giants" of the 1950s and 1960s, to over 40 actively practicing pediatric radiologists. Clinical excellence, commitment to teaching, and advancement of knowledge through research remain the goals and ideals, much as they were many years ago. Philadelphia has been a fertile home and environment for this development, mostly because of outstanding leaders and role models who have trained and influenced generations of pediatric radiologists. The purpose of this article is to tell the story of this growth and development and to explore the intellectual origins, professional "genealogy," and legacies left by those who created this tradition.

  8. Why support a women's medical college? Philadelphia's early male medical pro-feminists.

    Science.gov (United States)

    Peitzman, Steven J

    2003-01-01

    The male founders and early faculty of Philadelphia's Woman's Medical College were mostly abolitionist physicians, zealous moralists for whom medical feminism formed only one of the cherished causes they could "manfully" and righteously defend. Male faculty of the late nineteenth century comprised "self-made" men, mostly new specialists, for whom strict sexism probably seemed inconsistent with progressive medicine. For some of these physicians-obviously a small minority-defending medical women and breaking the barriers of fraternity could be consistent with "manly" responsibility. The outcome of the collaboration of women and the dissident men physicians in nineteenth-century Philadelphia amounted to another seeming paradox: the majority of the male medical profession, both locally and nationally, tyrannically hindered women's entry into the profession, yet medicine opened its doors in advance of law and the clergy; and where this first occurred, such as in the community centered on Woman's Medical College, a novel gender rearrangement arose based on collaboration and friendship.

  9. Trend Analyses of Users of a Syringe Exchange Program in Philadelphia, Pennsylvania: 1999-2014.

    Science.gov (United States)

    Maurer, Laurie A; Bass, Sarah Bauerle; Ye, Du; Benitez, José; Mazzella, Silvana; Krafty, Robert

    2016-12-01

    This study examines trends of injection drug users' (IDUs) use of a Philadelphia, Pennsylvania, syringe exchange program (SEP) from 1999 to 2014, including changes in demographics, drug use, substance abuse treatment, geographic indicators, and SEP use. Prevention Point Philadelphia's SEP registration data were analyzed using linear regression, Pearson's Chi square, and t-tests. Over time new SEP registrants have become younger, more racially diverse, and geographically more concentrated in specific areas of the city, corresponding to urban demographic shifts. The number of new registrants per year has decreased, however syringes exchanged have increased. Gentrification, cultural norms, and changes in risk perception are believed to have contributed to the changes in SEP registration. Demographic changes indicate outreach strategies for IDUs may need adjusting to address unique barriers for younger, more racially diverse users. Implications for SEPs are discussed, including policy and continued ability to address current public health threats.

  10. Striving for Gender Equity in Academic Medicine Careers: A Call to Action.

    Science.gov (United States)

    Bates, Carol; Gordon, Lynn; Travis, Elizabeth; Chatterjee, Archana; Chaudron, Linda; Fivush, Barbara; Gulati, Martha; Jagsi, Reshma; Sharma, Poonam; Gillis, Marin; Ganetzky, Rebecca; Grover, Amelia; Lautenberger, Diana; Moses, Ashleigh

    2016-08-01

    Women represent approximately half of students entering medical schools and more than half of those entering PhD programs. When advancing through the academic and professional fields, however, women continually face barriers that men do not. In this Commentary, the authors offer ideas for coordinating the efforts of organizations, academic institutions, and leaders throughout the scientific and medical professions to reduce barriers that result in inequities and, instead, strive for gender parity. Specific areas of focus outlined by the authors include facilitating women's access to formal and informal professional networks, acknowledging and addressing the gender pay gap as well as the lack of research funding awarded to women in the field, and updating workplace policies that have not evolved to accommodate women's lifestyles. As academic institutions seek access to top talent and the means to develop those individuals capable of generating the change medicine and science needs, the authors urge leaders and change agents within academic medicine to address the systemic barriers to gender equity that impede us from achieving the mission to improve the health of all.

  11. White paper on science and technology, 1997. Striving for an open research community

    International Nuclear Information System (INIS)

    1997-01-01

    This report concerns the policy measures intended to promote science and technology, pursuant to Article 8 of the Science and Technology Basic Law (Law No. 130), enacted in 1995. This report is constituted from three parts. Part 1 and 2 discuss trends in a wide range of scientific and technological activities to help the reader understand the policy measures implemented to promote science and technology, which are then discussed in Part 3. Part 1, titled 'striving for an open research community', attempt an analysis of reform and current and future issues addressed in the Science and Technology Basic Plan, which was enacted in July, 1996. Part 2 uses various data to compare scientific and technological activities in Japan with those in other selected countries. Part 3 relates to policies implanted for the promotion of science and technology in the Science and Technology Agency, Japan Government. Here is described on science and technology policy development, development of comprehensive and systematic policies and promotion of research activities. (G.K.)

  12. Self-regulation of health behavior: social psychological approaches to goal setting and goal striving.

    Science.gov (United States)

    Mann, Traci; de Ridder, Denise; Fujita, Kentaro

    2013-05-01

    The goal of this article is to review and highlight the relevance of social psychological research on self-regulation for health-related theory and practice. We first review research on goal setting, or determining which goals to pursue and the criteria to determine whether one has succeeded. We discuss when and why people adopt goals, what properties of goals increase the likelihood of their attainment, and why people abandon goals. We then review research on goal striving, which includes the planning and execution of actions that lead to goal attainment, and the processes that people use to shield their goals from being disrupted by other competing goals, temptations, or distractions. We describe four types of strategies that people use when pursuing goals. We find that self-regulation entails the operation of a number of psychological mechanisms, and that there is no single solution that will help all people in all situations. We recommend a number of strategies that can help people to more effectively set and attain health-related goals. We conclude that enhancing health behavior requires a nuanced understanding and sensitivity to the varied, dynamic psychological processes involved in self-regulation, and that health is a prototypical and central domain in which to examine the relevance of these theoretical models for real behavior. We discuss the implications of this research for theory and practice in health-related domains. PsycINFO Database Record (c) 2013 APA, all rights reserved.

  13. How might global health master deadly sins and strive for greater virtues?

    Directory of Open Access Journals (Sweden)

    Catherine Panter-Brick

    2014-03-01

    Full Text Available In the spirit of critical reflection, we examine how the field of global health might surmount current challenges and prioritize its ethical mandate, namely to achieve, for all people, equity in health. We use the parlance of mastering deadly sins and striving for greater virtues in an effort to review what is needed to transform global health action. Global health falls prey to four main temptations: coveting silo gains, lusting for technological solutions, leaving broad promises largely unfulfilled, and boasting of narrow successes. This necessitates a change of heart: to keep faith with the promise it made, global health requires a realignment of core values and a sharper focus on the primacy of relationships with the communities it serves. Based on the literature to date, we highlight six steps to re-orienting global health action. Articulating a coherent global health agenda will come from principled action, enacted through courage and prudence in decision-making to foster people-centered systems of care over the entire lifespan.

  14. Health and housing collaboration at LAST: the Philadelphia Lead Abatement Strike Team.

    OpenAIRE

    Campbell, Carla; Himmelsbach, Robert; Palermo, Peter; Tobin, Richard

    2005-01-01

    The Lead Abatement Strike Team (LAST) was developed in 2002 by the Philadelphia Department of Public Health (PDPH) in response to community concern about management of children with elevated blood lead levels (EBLLs). Fourteen hundred backlog properties (housing at least one child with EBLLs) were identified through inspection as having housing-based lead hazards for which no satisfactory environmental remediation (control of lead hazards) had been achieved. In the first two years of LAST, 83...

  15. [Acute transformation of chronic myeloid leukemia: disappearance of the Philadelphia chromosome after autograft].

    Science.gov (United States)

    Reiffers, J; David, B; Bernard, P; Vezon, G; Marit, G; Moulinier, J; Broustet, A

    1984-04-12

    Two patients with chronic granulocytic leukemia (C.G.L.) undergoing transformation were treated by high dose chemotherapy and total body irradiation followed by autografting of hematopoietic stem cells collected and cryo-preserved at the time of diagnosis. Recovery of hematopoiesis was characterized by disappearance of the Philadelphia chromosome in most metaphases. A new approach of the management of C.G.L. is discussed.

  16. Herbarium specimens, photographs, and field observations show Philadelphia area plants are responding to climate change.

    Science.gov (United States)

    Panchen, Zoe A; Primack, Richard B; Anisko, Tomasz; Lyons, Robert E

    2012-04-01

    The global climate is changing rapidly and is expected to continue changing in coming decades. Studying changes in plant flowering times during a historical period of warming temperatures gives us a way to examine the impacts of climate change and allows us to predict further changes in coming decades. The Greater Philadelphia region has a long and rich history of botanical study and documentation, with abundant herbarium specimens, field observations, and botanical photographs from the mid-1800s onward. These extensive records also provide an opportunity to validate methodologies employed by other climate change researchers at a different biogeographical area and with a different group of species. Data for 2539 flowering records from 1840 to 2010 were assessed to examine changes in flowering response over time and in relation to monthly minimum temperatures of 28 Piedmont species native to the Greater Philadelphia region. Regression analysis of the date of flowering with year or with temperature showed that, on average, the Greater Philadelphia species studied are flowering 16 d earlier over the 170-yr period and 2.7 d earlier per 1°C rise in monthly minimum temperature. Of the species studied, woody plants with short flowering duration are the best indicators of a warming climate. For monthly minimum temperatures, temperatures 1 or 2 mo prior to flowering are most significantly correlated with flowering time. Studies combining herbarium specimens, photographs, and field observations are an effective method for detecting the effects of climate change on flowering times.

  17. Using Multispectral Analysis in GIS to Model the Potential for Urban Agriculture in Philadelphia

    Science.gov (United States)

    Dmochowski, J. E.; Cooper, W. P.

    2010-12-01

    In the context of growing concerns about the international food system’s dependence on fossil fuels, soil degradation, climate change, and other diverse issues, a number of initiatives have arisen to develop and implement sustainable agricultural practices. Many seeking to reform the food system look to urban agriculture as a means to create localized, sustainable agricultural production, while simultaneously providing a locus for community building, encouraging better nutrition, and promoting the rebirth of depressed urban areas. The actual impact of such system, however, is not well understood, and many critics of urban agriculture regard its implementation as impractical and unrealistic. This project uses multispectral imagery from United States Department of Agriculture’s National Agricultural Imagery Program with a one-meter resolution to quantify the potential for increasing urban agriculture in an effort to create a sustainable food system in Philadelphia. Color infrared images are classified with a minimum distance algorithm in ArcGIS to generate baseline data on vegetative cover in Philadelphia. These data, in addition to mapping on the ground, form the basis of a model of land suitable for conversion to agriculture in Philadelphia, which will help address questions related to potential yields, workforce, and energy requirements. This research will help city planners, entrepreneurs, community leaders, and citizens understand how urban agriculture can contribute to creating a sustainable food system in a major North American city.

  18. Using Randomized Clinical Trials to Determine the Impact of Reading Intervention on Struggling Adolescent Readers: Reports of Research from Five Nationally Funded Striving Readers Grants

    Science.gov (United States)

    Loadman, William; Sprague, Kim; Hamilton, Jennifer; Coffey, Deb; Faddis, Bonnie

    2010-01-01

    In 2005, the U.S. Department of Education awarded eight Striving Readers grants to projects around the country. The goal of Striving Readers is to improve literacy skills and achievement for struggling readers in middle and high school and to increase the research base using randomized clinical research to address improvement in adolescent…

  19. An historical overview of the first two decades of striving towards Safe Motherhood.

    Science.gov (United States)

    Maclean, Gaynor D

    2010-02-01

    The paper examines some of the progress and problems encountered during the first two decades of the Safe Motherhood Initiative. Sufficient statistics are cited to identify the immensity of the persisting problems associated with maternal death and morbidity before the study focuses on some of the endeavours designed to enable women to survive their natural function of giving birth. Varying attitudes and approaches that have characterised the initiatives launched in the past 20 years are reviewed and their changing emphases noted. The stress on treating the medical causes of maternal death in the early years have been complemented by increasing attention to social and political issues as time has elapsed. The advent of the Millennium Development Goals (MDGs) has impelled efforts to provide skilled attendance for all women during childbirth; the poor, socially disadvantaged and vulnerable being those most at risk. MDG 5, concerning maternal health, is perceived as pivotal in the context of global development. Maternal death when viewed from the human rights perspective is perceived as a social injustice rather than a health disadvantage and Safe Motherhood is currently considered increasingly as a basic human right. The study offers a synthesis of concepts and actions that are contributing to building Safe Motherhood across the globe in the 21st century. In considering the factors that inhibit the degree of safety associated with giving birth, global efforts that are tackling a persisting buffer zone are identified and continuous action urged in order to strive towards the targets set for 2015. Copyright © 2009 Elsevier B.V. All rights reserved.

  20. Chinese Foreign Policy in a Global Perspective: A Responsible Reformer "Striving For Achievement"

    Directory of Open Access Journals (Sweden)

    Mikael Weissmann

    2015-12-01

    Full Text Available During the last four decades, China has moved from being an isolated country separated from the international community to having become one of the world’s major powers. It is vital to understand what is guiding Chinese foreign policy, why this is so, and not least what kind of power China is and will be in the future. This article analyses the vital elements and thinking that guides Chinese foreign policy, its priorities and decision making process. It is found that China's foreign policy is embedded in domestic issues. The foremost foreign policy objective is domestic political stability, which in turn is a necessity for the survival of one-party rule. Both are dependent on a combination of two key factors: continuing domestic economic growth and nationalism. The foreign policy is also closely linked to the Chinese self-perception, both its self-superiority/self-inferiority dualism and its multitude of confusing (overlapping identities about what China is and should be. A key turning year is 2008 when the "global" financial crisis severely affected the United States and Europe at a time of Chinese economic success, which gave China confidence to pursue a more active and aggressive/assertive stance on the international stage. It is concluded that China under Xi Jinping will not be a status que power accepting the world as it is, but nor are we to expect China to become a revisionist power aiming to remodel the global order. China is what can best be described as a responsible reformer "striving for achievements".

  1. The People Paradox: Self-Esteem Striving, Immortality Ideologies, and Human Response to Climate Change

    Directory of Open Access Journals (Sweden)

    Janis L. Dickinson

    2009-06-01

    Full Text Available In 1973, Ernest Becker, a cultural anthropologist cross-trained in philosophy, sociology, and psychiatry, invoked consciousness of self and the inevitability of death as the primary sources of human anxiety and repression. He proposed that the psychological basis of cooperation, competition, and emotional and mental health is a tendency to hold tightly to anxiety-buffering cultural world views or "immortality projects" that serve as the basis for self-esteem and meaning. Although he focused mainly on social and political outcomes like war, torture, and genocide, he was increasingly aware that materialism, denial of nature, and immortality-striving efforts to control, rather than sanctify, the natural world were problems whose severity was increasing. In this paper I review Becker's ideas and suggest ways in which they illuminate human response to global climate change. Because immortality projects range from belief in technology and materialism to reverence for nature or belief in a celestial god, they act both as barriers to and facilitators of sustainable practices. I propose that Becker's cross-disciplinary "science of man," and the predictions it generates for proximate-level determinants of social behavior, add significantly to our understanding of and potential for managing the people paradox, i.e., that the very things that bring us symbolic immortality often conflict with our prospects for survival. Analysis of immortality projects as one of the proximate barriers to addressing climate change is both cautionary and hopeful, providing insights that should be included in the cross-disciplinary quest to uncover new pathways toward rational, social change.

  2. A striving for independence: a qualitative study of women living with vertebral fracture

    Directory of Open Access Journals (Sweden)

    Toss Göran

    2010-04-01

    Full Text Available Abstract Background Quantitative studies using generic and disease-specific health-related quality of life (HRQOL questionnaires have shown that osteoporosis-related vertebral fractures have a significant negative effect on HRQOL, but there are only few studies that address what it means to live with vertebral fracture from a deeper experiential perspective. How HRQOL and daily life are affected several years after vertebral fracture and how women cope with this are more unclear. This study aimed to describe how HRQOL and daily life had been affected in women with vertebral fracture several years after diagnosis. Methods The study design was qualitative. Semi-structured interviews were conducted with ten Swedish women during 2008. Data were analysed using qualitative inductive content analysis. Results The findings of this study revealed three themes related to the influence on HRQOL and daily life: A threatened independence, i.e. back pain, anxiety, negative impact on self-image and consequences in daily life; Strategies for maintaining independence, i.e. coping, self-care and support; and The importance of maintaining independence, i.e. the ability to perform everyday activities, social interaction and having something meaningful to do. The women were striving for independence or maintaining their independence by trying to manage different types of symptoms and consequences in different ways. Conclusion HRQOL and daily life were strongly affected in a negative way by the impact of the vertebral fracture. Information from this study may provide new knowledge and understanding of the women's experiences of living with vertebral fracture from an insider's point of view in order to obtain a deeper understanding of the women's everyday life. However, further evaluation is still needed in larger study groups.

  3. A striving for independence: a qualitative study of women living with vertebral fracture.

    Science.gov (United States)

    Hallberg, Inger; Ek, Anna-Christina; Toss, Göran; Bachrach-Lindström, Margareta

    2010-04-16

    Quantitative studies using generic and disease-specific health-related quality of life (HRQOL) questionnaires have shown that osteoporosis-related vertebral fractures have a significant negative effect on HRQOL, but there are only few studies that address what it means to live with vertebral fracture from a deeper experiential perspective. How HRQOL and daily life are affected several years after vertebral fracture and how women cope with this are more unclear. This study aimed to describe how HRQOL and daily life had been affected in women with vertebral fracture several years after diagnosis. The study design was qualitative. Semi-structured interviews were conducted with ten Swedish women during 2008. Data were analysed using qualitative inductive content analysis. The findings of this study revealed three themes related to the influence on HRQOL and daily life: A threatened independence, i.e. back pain, anxiety, negative impact on self-image and consequences in daily life; Strategies for maintaining independence, i.e. coping, self-care and support; and The importance of maintaining independence, i.e. the ability to perform everyday activities, social interaction and having something meaningful to do. The women were striving for independence or maintaining their independence by trying to manage different types of symptoms and consequences in different ways. HRQOL and daily life were strongly affected in a negative way by the impact of the vertebral fracture. Information from this study may provide new knowledge and understanding of the women's experiences of living with vertebral fracture from an insider's point of view in order to obtain a deeper understanding of the women's everyday life. However, further evaluation is still needed in larger study groups.

  4. [Disappearance of a Philadelphia chromosome-positive clone and appearance of a -negative clone following treatment with imatinib mesylate in acute myelomonocytic leukemia].

    Science.gov (United States)

    Takahashi, Wataru; Arai, Yukihiro; Tadokoro, Jiro; Takeuchi, Kengo; Yamagata, Tetsuya; Mitani, Kinuko

    2006-02-01

    A 63-year-old female was diagnosed as having Philadelphia chromosome-positive acute myelomonocytic leukemia in June 2002. The patient received monotherapy with imatinib mesylate or combination therapy with DCM and idarubicin/cytarabine, both of which failed in attaining disease remission. However, the second imatinib administration plus CAG therapy resulted in disappearance of the Philadelphia chromosome-positive clone and increase of Philadelphia chromosome-negative cells. During a therapy-withholding period due to fungal infection, the Philadelphia chromosome-positive clone expanded and the patient died of cerebral hemorrhage in February 2003. The transient suppression of the Philadelphia chromosome-positive clone may have brought about amplification of the Philadelphia chromosome-negative cells after the secondary imatinib treatment.

  5. Evaluation and comparison of electric propulsion motors for submarines

    OpenAIRE

    Harbour, Joel P.

    2001-01-01

    CIVINS (Civilian Institutions) Thesis document The Navy has announced its conviction to make its warships run on electric power through the decision to make its newest line of destroyers propelled with an electric propulsion system. Several ship construction firms and electric motor manufacturers are thus striving to develop enabling technology, including high power density motors. The purpose of this thesis is to evaluate some of the proposed motor designs for use in a submarine. Permanen...

  6. The Buried Past: An Archaeological History of Philadelphia, by John L. Cotter, Daniel G. Roberts, and Michael Parrington. University of Pennsylvania Press, Philadelphia. 1992

    Directory of Open Access Journals (Sweden)

    James A. Delle

    1995-05-01

    Full Text Available Having been involved in both contract and academic archaeology in recent years, I have heard (and sympathized with a pervasive lament. It seems increasingly common that even the best contract archaeology is rarely published, but compiled into reports that disappear into state repositories and contract firm offices, never again to be thought of except (maybe when it comes time to write the next report. There is an increasing body of both gray literature and gray excavation: work that is done in compliance with state and federal laws but which never reaches an audience of more than a dozen or so readers. Given this discouraging trend, the compendious The Buried Past is a welcomed synthesis of several generations of aca­demic and CRM investigations into the historical archaeology of the Greater Philadelphia region.

  7. Improving Access to Eye Care among Persons at High-Risk of Glaucoma in Philadelphia — Design and Methodology: The Philadelphia Glaucoma Detection and Treatment Project

    Science.gov (United States)

    Myers, Jonathan S.; Henderer, Jeffrey; Crews, John E.; Saaddine, Jinan B.; Molineaux, Jeanne; Johnson, Deiana; Sembhi, Harjeet; Stratford, Shayla; Suleiman, Ayman; Pizzi, Laura; Spaeth, George L.; Katz, L. Jay

    2016-01-01

    Purpose The Wills Eye Glaucoma Research Center initiated a 2-year demonstration project to develop and implement a community-based intervention to improve detection and management of glaucoma in Philadelphia. Methods The glaucoma detection examination consisted of: ocular, medical, and family history; visual acuity testing; corneal pachymetry; biomicroscopy of the anterior segment; intraocular pressure (IOP) measurement; gonioscopy; funduscopy; automated visual field testing; and fundus-color photography. Treatment included laser surgery and/or IOP-lowering medication. A cost analysis was conducted to understand resource requirements. Outcome measures included; prevalence of glaucoma-related pathology and other eye diseases among high-risk populations; the impact of educational workshops on level of knowledge about glaucoma (assessed by pre- and post-test evaluation); and patient satisfaction of the glaucoma detection examinations in the community (assessed by satisfaction survey). Treatment outcome measures were change in IOP at 4–6 weeks and 4–6 months following selective laser trabeculoplasty treatment, deepening of the anterior chamber angle following laser-peripheral iridotomy treatment, and rate of adherence to recommended follow-up examinations. Cost outcomes included total program costs, cost per case of glaucoma detected, and cost per case of ocular disease detected. Results This project enrolled 1649 participants (African Americans aged 50+ years, adults 60+ years and individuals with a family history of glaucoma). A total of 1074 individuals attended a glaucoma educational workshop and 1508 scheduled glaucoma detection examination appointments in the community setting. Conclusions The Philadelphia Glaucoma Detection and Treatment Project aimed to improve access and use of eye care and to provide a model for a targeted community-based glaucoma program. PMID:26950056

  8. Improving Access to Eye Care among Persons at High-Risk of Glaucoma in Philadelphia--Design and Methodology: The Philadelphia Glaucoma Detection and Treatment Project.

    Science.gov (United States)

    Hark, Lisa; Waisbourd, Michael; Myers, Jonathan S; Henderer, Jeffrey; Crews, John E; Saaddine, Jinan B; Molineaux, Jeanne; Johnson, Deiana; Sembhi, Harjeet; Stratford, Shayla; Suleiman, Ayman; Pizzi, Laura; Spaeth, George L; Katz, L Jay

    2016-01-01

    The Wills Eye Glaucoma Research Center initiated a 2-year demonstration project to develop and implement a community-based intervention to improve detection and management of glaucoma in Philadelphia. The glaucoma detection examination consisted of: ocular, medical, and family history; visual acuity testing; corneal pachymetry; biomicroscopy of the anterior segment; intraocular pressure (IOP) measurement; gonioscopy; funduscopy; automated visual field testing; and fundus-color photography. Treatment included laser surgery and/or IOP-lowering medication. A cost analysis was conducted to understand resource requirements. Outcome measures included; prevalence of glaucoma-related pathology and other eye diseases among high-risk populations; the impact of educational workshops on level of knowledge about glaucoma (assessed by pre- and post-test evaluation); and patient satisfaction of the glaucoma detection examinations in the community (assessed by satisfaction survey). Treatment outcome measures were change in IOP at 4-6 weeks and 4-6 months following selective laser trabeculoplasty treatment, deepening of the anterior chamber angle following laser-peripheral iridotomy treatment, and rate of adherence to recommended follow-up examinations. Cost outcomes included total program costs, cost per case of glaucoma detected, and cost per case of ocular disease detected. This project enrolled 1649 participants (African Americans aged 50+ years, adults 60+ years and individuals with a family history of glaucoma). A total of 1074 individuals attended a glaucoma educational workshop and 1508 scheduled glaucoma detection examination appointments in the community setting. The Philadelphia Glaucoma Detection and Treatment Project aimed to improve access and use of eye care and to provide a model for a targeted community-based glaucoma program.

  9. Can agonistic striving lead to unexplained illness? Implicit goals, pain tolerance, and somatic symptoms in adolescents and adults.

    Science.gov (United States)

    Ewart, Craig K; Elder, Gavin J; Laird, Kelsey T; Shelby, Grace D; Walker, Lynn S

    2014-09-01

    We tested the social action theory hypotheses that (a) psychological stress induced by struggling to control others (agonistic striving) is associated with higher levels of subjective somatic symptoms than stress induced by struggling to control the self (transcendence striving); (b) the association between agonistic striving and symptoms is moderated by the ability to tolerate pain; and (c) associations among agonistic goals, pain tolerance, and subjective symptoms are not explained by personality and affective traits or negative emotional responses to personal stressors. Implicit motives and negative emotional reactivity to recurring personal stressors were assessed by Social Competence Interview in 333 adolescents and adults who participated in longitudinal research on functional abdominal pain at a university medical center. Pain tolerance was assessed by graduated thermal pain protocol; subjective somatic symptoms, and personality/affective traits assessed by questionnaires. The primary outcome measure was the self-reported severity of 35 somatic symptoms often experienced in the absence of diagnosable disease. All hypotheses were supported. Nonconscious agonistic strivings may increase the perceived frequency and severity of subjective somatic symptoms; this tendency is greatly magnified by difficulty in self-regulating responses to painful stimuli. Implicit agonistic motives and their associations with symptoms are not explained by individual differences in trait neuroticism, anxiety, depression, anger, or low self-esteem or by negative emotional reactivity to a personal stressor. These findings may afford fruitful insights into mechanisms by which stressful social environments undermine health and suggest promising directions for clinical intervention. (PsycINFO Database Record (c) 2014 APA, all rights reserved).

  10. The Short-Term Impacts of the Philadelphia Beverage Tax on Beverage Consumption.

    Science.gov (United States)

    Zhong, Yichen; Auchincloss, Amy H; Lee, Brian K; Kanter, Genevieve P

    2018-04-11

    On January 1, 2017, Philadelphia implemented a beverage tax of $0.015/ounce on sugar ("regular") and sugar-substitute ("diet") beverages. The purpose of this study was to evaluate the immediate impact of the tax on residents' consumption of soda, fruit drinks, energy drinks, and bottled water. A repeat cross-sectional study design used data from a random-digit-dialing phone survey during a no-tax period (December 6-31, 2016) and a tax period (January 15-February 31, 2017) among 899 respondents in Philadelphia, Pennsylvania, and 878 respondents in three nearby comparison cities. Survey questions included frequency and volume of bottled water and beverages. Outcomes were daily consumption, and 30-day consumption frequency and volume. Propensity score-weighted difference-in-differences regression was used to control for secular time trend and confounding. Covariates were sociodemographics, BMI, health status, smoking, and alcohol use. Analyses were conducted in 2017. Within the first 2 months of tax implementation, relative to the comparison cities, in Philadelphia the odds of daily consumption of regular soda was 40% lower (OR=0.6, 95% CI=0.37, 0.97); energy drink was 64% lower (OR=0.36, 95% CI=0.17, 0.76); bottled water was 58% higher (OR=1.58, 95% CI=1.13, 2.20); and the 30-day regular soda consumption frequency was 38% lower (ratio of consumption frequency=0.62, 95% CI=0.40, 0.98). Early results suggest that the tax influenced daily consumption of regular soda, energy drinks, and bottled water. Future studies are needed to evaluate longer-term impact of the tax on sugared beverage consumption and substitutions. Copyright © 2018 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

  11. Phylogenetic reconstruction of the Legionella pneumophila Philadelphia-1 laboratory strains through comparative genomics.

    Directory of Open Access Journals (Sweden)

    Chitong Rao

    Full Text Available Over 20 years ago, two groups independently domesticated Legionella pneumophila from a clinical isolate of bacteria collected during the first recognized outbreak of Legionnaires' disease (at the 1976 American Legion's convention in Philadelphia. These two laboratory strains, JR32 and Lp01, along with their derivatives, have been disseminated to a number of laboratories around the world and form the cornerstone of much of the research conducted on this important pathogen to date. Nevertheless, no exhaustive examination of the genetic distance between these strains and their clinical progenitor has been performed thus far. Such information is of paramount importance for making sense of several phenotypic differences observed between these strains. As environmental replication of L. pneumophila is thought to exclusively occur within natural protozoan hosts, retrospective analysis of the domestication and axenic culture of the Philadelphia-1 progenitor strain by two independent groups also provides an excellent opportunity to uncover evidence of adaptation to the laboratory environment. To reconstruct the phylogenetic relationships between the common laboratory strains of L. pneumophila Philadelphia-1 and their clinical ancestor, we performed whole-genome Illumina resequencing of the two founders of each laboratory lineage: JR32 and Lp01. As expected from earlier, targeted studies, Lp01 and JR32 contain large deletions in the lvh and tra regions, respectively. By sequencing additional strains derived from Lp01 (Lp02 and Lp03, we retraced the phylogeny of these strains relative to their reported ancestor, thereby reconstructing the evolutionary dynamics of each laboratory lineage from genomic data.

  12. Second malignancies in hydroxyurea and interferon-treated Philadelphia-negative myeloproliferative neoplasms

    DEFF Research Database (Denmark)

    Hansen, Iben Onsberg; Sørensen, Anders Lindholm; Hasselbalch, Hans Carl

    2017-01-01

    OBJECTIVE: In an era of controversy in regard to 'hydroxyurea-leukaemogenicity' and when interferon-alfa2 (IFN) is being revived in the treatment of Philadelphia-negative myeloproliferative neoplasms (MPNs), we aim in this single-centre observational study to describe the frequencies of second...... malignancies in a cohort of MPN patients treated with hydroxyurea (HU) or IFN monotherapy or the combination of these agents. PATIENTS AND METHODS: Records of a MPN cohort of 196 patients were reviewed, and a retrospective analysis was performed on 90 patients treated with HU, 38 patients treated with IFN...

  13. [Control discourses and power relations of yellow fever: Philadelphia in 1793].

    Science.gov (United States)

    Kim, Seohyung

    2014-12-01

    1793 Yellow fever in Philadelphia was the most severe epidemics in the late 18th century in the United States. More than 10% of the population in the city died and many people fled to other cities. The cause of yellow fever in the United States had close relationship with slaves and sugar in Philadelphia. Sugarcane plantation had needed many labors to produce sugar and lots of Africans had to move to America as slaves. In this process, Aëdes aegypti, the vector of yellow fever had migrated to America and the circumstances of ships or cities provided appropriate conditions for its breeding. In this period, the cause of yellow fever could not be established exactly, so suggestions of doctors became entangled in political and intellectual discourses in American society. There was a critical conflict between Jeffersonian Republicanism and Federalism about the origin and treatment of yellow fever. Benjamin Rush, a Jeffersonian Republican, suggested urban sanitation reform and bloodletting. He believed the infectious disease happened because of unsanitary city condition, so he thought the United States could be a healthy nation by improvement of the public health and sanitation. He would like to cope with national crisis and develop American society on the basis of republicanism. While Rush suggested the improvement of public health and sanitation, the city government of Philadelphia suggested isolation of yellow fever patients and quarantine. City government isolated the patients from healthy people and it reconstructed space of hospital. Also, it built orphanages to take care of children who lost their parents during the epidemic and implemented power to control people put in the state of exception. Of course, city government tried to protect the city and nation by quarantine of every ship to Philadelphia. Control policies of yellow fever in 1793 showed different conflicts and interactions. Through the yellow fever, Jeffersonian Republicanism and Federalism had

  14. Secondhand Smoke Exposure and Smoke-free Policy in Philadelphia Public Housing.

    Science.gov (United States)

    Klassen, Ann C; Lee, Nora L; Pankiewicz, Aaron; Ward, Rikki; Shuster, Michelle; Ogbenna, Bethany Townsend; Wade, Anita; Boamah, Maxwell; Osayameh, Olufunlayo; Rule, Ana M; Szymkowiak, Dorota; Coffman, Ryan; Bragg, Virginius; Mallya, Giridhar

    2017-04-01

    Multi-unit housing environments remain significant sources of secondhand smoke (SHS) exposure, especially for vulnerable populations in subsidized housing. In Philadelphia, the largest US housing authority to implement smoke-free policies, we measured baseline resident smoking-related behaviors and attitudes, and longitudinal exposures to airborne nicotine, during policy development and implementation. In 4 communities, we collected data in 2013, 2014, and 2016, before and after introduction of comprehensive smoke-free policies, interviewing persons in 172 households, and monitoring air-borne nicotine in non-smoking homes and public areas. Average nicotine level differences across years were estimated with multi-level models. Fifty-six percent of respondents smoked. Only 37% of households were smoke-free, with another 41% restricting smoking by area or time of day. The number of locations with detectable nicotine did not differ before and after policy implementation, with approximately 20% of non-smoking homes and 70%-80% of public areas having detectable nicotine. However, public area nicotine levels were lower in 2016, after policy implementation, than in 2013 and 2014 (-0.19 μg/m 3 , p = .03). Findings suggest that initial policy implementation was associated with reduced SHS exposure in Philadelphia. As HUD strengthens smoke-free policies, SHS monitoring can be useful to educate stakeholders and build support for policy enforcement.

  15. OZONE PRODUCTION IN THE PHILADELPHIA URBAN AREA DURING NE-OPS 99

    International Nuclear Information System (INIS)

    KLEINMAN, L.I.; DAUM, P.H.; BRECHTEL, F.; LEE, Y.N.; NUNNERMACKER, L.J.; SPRINGSTON, S.R.; WEINSTEIN-LLOYD, J.

    2001-01-01

    As part of the 1999 NARSTO Northeast Oxidant and Particulate Study (NE-OPS) field campaign, the DOE G-1 aircraft sampled trace gases and aerosols in and around the Philadelphia metropolitan area. Twenty research flights were conducted between July 25 and August 11. The overall goals of these flights were to obtain a mechanistic understanding of O(sub 3) production; to characterize the spatial and temporal behavior of photo-oxidants and aerosols; and to study the evolution of aerosol size distributions, including the process of new particle formation. Within the NE-OPS program, other groups provided additional trace gas, aerosol, and meteorological observations using aircraft, balloon, remote sensing, and surface based instruments (Phillbrick et al., 2000). In this article we provide an overview of the G-1 observations related to O(sub 3) production, focusing on the vertical distribution of pollutants. Ozone production rates are calculated using a box model that is constrained by observed trace gas concentrations. Highest O(sub 3) concentrations were observed on July 31, which we present as a case study. On that day, O(sub 3) concentrations above the 1-hour 120 ppb standard were observed downwind of Philadelphia and also in the plume of a single industrial facility located on the Delaware River south of the city

  16. Young People Take Their Rightful Places as Full and Contributing Members of a World Class Workforce: Philadelphia Youth Network Annual Report 2006

    Science.gov (United States)

    Philadelphia Youth Network, 2006

    2006-01-01

    The title of this year's annual report has particular meaning for all of the staff at the Philadelphia Youth Network. The phrase derives from Philadelphia Youth Network's (PYN's) new vision statement, developed as part of its recent strategic planning process, which reads: All of our city's young people take their rightful places as full and…

  17. Acceptance of Others, Feeling of Being Accepted and Striving for Being Accepted Among the Representatives of Different Kinds of Occupations

    Directory of Open Access Journals (Sweden)

    Gergana Stanoeva

    2012-05-01

    Full Text Available This paper deals with an important issue related to the human attitudes and needs in interpersonal and professional aspects. The theoretical part deals with several psychological components of the self-esteem and esteem of the others – acceptance of the others, feeling of being accepted, need for approval. Some gender differences in manifestations of acceptance and feeling of being accepted at the workplace are discussed. This article presents some empirical data for the degree of acceptance of others, feeling of being accepted and the strive for being accepted among the representatives of helping, pedagogical, administrative and economic occupations, as well as non-qualified workers. The goals of the study were to reveal the interdependency between these constructs and to be found some significant differences between the representatives of the four groups of occupations. The methods of the first study were W. Fey’s scales “Acceptance of others”, and “How do I feel accepted by others”. The method of the second study was Crown and Marlowe Scale for Social Desirability. The results indicated some significant differences in acceptance of others and feeling of being accepted between the non-qualified workers and the representatives of helping, administrative and economic occupations. There were not any significant difference in strive for being accepted between the fouroccupational groups.

  18. Goal striving strategies and effort mobilization: When implementation intentions reduce effort-related cardiac activity during task performance.

    Science.gov (United States)

    Freydefont, Laure; Gollwitzer, Peter M; Oettingen, Gabriele

    2016-09-01

    Two experiments investigate the influence of goal and implementation intentions on effort mobilization during task performance. Although numerous studies have demonstrated the beneficial effects of setting goals and making plans on performance, the effects of goals and plans on effort-related cardiac activity and especially the cardiac preejection period (PEP) during goal striving have not yet been addressed. According to the Motivational Intensity Theory, participants should increase effort mobilization proportionally to task difficulty as long as success is possible and justified. Forming goals and making plans should allow for reduced effort mobilization when participants perform an easy task. However, when the task is difficult, goals and plans should differ in their effect on effort mobilization. Participants who set goals should disengage, whereas participants who made if-then plans should stay in the field showing high effort mobilization during task performance. As expected, using an easy task in Experiment 1, we observed a lower cardiac PEP in both the implementation intention and the goal intention condition than in the control condition. In Experiment 2, we varied task difficulty and demonstrated that while participants with a mere goal intention disengaged from difficult tasks, participants with an implementation intention increased effort mobilization proportionally with task difficulty. These findings demonstrate the influence of goal striving strategies (i.e., mere goals vs. if-then plans) on effort mobilization during task performance. Copyright © 2016 Elsevier B.V. All rights reserved.

  19. Structural and Functional Characterization of a New Double Variant Haemoglobin (HbG-Philadelphia/Duarte α(2)β(2)).

    Science.gov (United States)

    Fais, Antonella; Casu, Mariano; Ruggerone, Paolo; Ceccarelli, Matteo; Porcu, Simona; Era, Benedetta; Anedda, Roberto; Sollaino, Maria Carla; Galanello, Renzo; Corda, Marcella

    2011-01-01

    WE REPORT THE FIRST CASE OF COSEGREGATION OF TWO HAEMOGLOBINS (HBS): HbG-Philadelphia [α68(E17)Asn → Lys] and HbDuarte [β62(E6)Ala → Pro]. The proband is a young patient heterozygous also for β°-thalassaemia. We detected exclusively two haemoglobin variants: HbDuarte and HbG-Philadelphia/Duarte. Functional study of the new double variant HbG-Philadelphia/Duarte exhibited an increase in oxygen affinity, with a slight decrease of cooperativity and Bohr effect. This functional behaviour is attributed to β62Ala → Pro instead of α68Asn → Lys substitution. Indeed, HbG-Philadelphia isolated in our laboratory from blood cells donor carrier for this variant is not affected by any functional modification, whereas purified Hb Duarte showed functional properties very similar to the double variant. NMR and MD simulation studies confirmed that the presence of Pro instead of Ala at the β62 position produces displacement of the E helix and modifications of the tertiary structure. The substitution α68(E17)Asn → Lys does not cause significant structural and dynamical modifications of the protein. A possible structure-based rational of substitution effects is suggested.

  20. Dasatinib crosses the blood-brain barrier and is an efficient therapy for central nervous system philadelphia chromosome positive leukemia

    NARCIS (Netherlands)

    K. Porkka (Kimmo); P. Koskenvesa (Perttu); T. Lundan (Tuija); J. Rimpiläinen (Johanna); S. Mustjoki (Satu); R. Smykla (Richard); R. Wild (Robert); R. Luo (Roger); M. Arnan (Montserrat); B. Brethon (Benoit); L. Eccersley (Lydia); H. Hjorth-Hansen (Henrik); M. Höglund (Martin); H. Klamova (Hana); H. Knutsen (Håvar); S. Parikh (Suhag); E. Raffoux (Emmanuel); F. Gruber (Franz); F. Brito-Babapulle (Finella); H. Dombret (Hervé); R.F. Duarte (Rafael); E. Elonen (Erkki); R. Paquette (Ron); C.M. Zwaan (Christian Michel); F.Y.F. Lee (Francis)

    2008-01-01

    textabstractAlthough imatinib, a BCR-ABL tyrosine kinase inhibitor, is used to treat acute Philadelphia chromosome-positive (Ph+) leukemia, it does not prevent central nervous system (CNS) relapses resulting from poor drug penetration through the blood-brain barrier. Imatinib and dasatinib (a

  1. 3-D Scanning of Headstones at the U.S. Naval Plot, Mount Moriah Cemetery, Philadelphia, PA

    Science.gov (United States)

    2017-11-17

    unrecognizable because these monuments of history provide a record of the heroes who served this country with honor and distinction. The naval plot at Mount...Eventually, 1 History of Philadelphia, 1609-1884, by John Thomas Scharf and Thompson...digital imaging requires natural or artificial light to work effec- tively. The point cloud is the most important aspect of this technology for

  2. Correlates to Human Papillomavirus Vaccination Status and Willingness to Vaccinate in Low-Income Philadelphia High School Students

    Science.gov (United States)

    Bass, Sarah B.; Leader, Amy; Shwarz, Michelle; Greener, Judith; Patterson, Freda

    2015-01-01

    Background: Little is known about the correlates of human papillomavirus (HPV) vaccination or willingness to be vaccinated in urban, minority adolescents. Methods: Using responses to the 2013 Youth Risk Behavior Survey in Philadelphia, a random sample of high schools provided weighted data representing 20,941 9th to 12th graders. Stratified by…

  3. NCI Helps Children’s Hospital of Philadelphia to Identify and Treat New Target in Pediatric Cancer | Poster

    Science.gov (United States)

    There may be a new, more effective method for treating high-risk neuroblastoma, according to scientists at the Children’s Hospital of Philadelphia and collaborators in the Cancer and Inflammation Program at NCI at Frederick. Together, the groups published a study describing a previously unrecognized protein on neuroblastoma cells, called GPC2, as well as the creation of a

  4. School Autonomy and District Support: How Principals Respond to a Tiered Autonomy Initiative in Philadelphia Public Schools

    Science.gov (United States)

    Steinberg, Matthew P.; Cox, Amanda Barrett

    2017-01-01

    A tiered autonomy policy was recently implemented in Philadelphia, where select principals were granted autonomy to manage school operations while others were promised greater district support to improve school functioning. This article provides evidence on how principals used their autonomy and the extent of district support for non-autonomous…

  5. Localization of preferential sites of rearrangement within the BCR gene in Philadelphia chromosome-positive acute lymphoblastic leukemia

    International Nuclear Information System (INIS)

    Denny, C.T.; Shah, N.P.; Ogden, S.; Willman, C.; McConnell, T.; Crist, W.; Carroll, A.; Witte, O.N.

    1989-01-01

    The Philadelphia chromosome associated with acute lymphoblastic leukemia (ALL) has been linked to a hybrid BCR/ABL protein product that differs from that found in chronic myelogenous leukemia. This implies that the molecular structures of the two chromosomal translocations also differ. Localization of translocation breakpoints in Philadelphia chromosome-positive ALL has been impeded due to the only partial characterization of the BCR locus. The authors have isolated the entire 130-kilobase BCR genomic locus from a human cosmid library. They have demonstrated that these breakpoints are all located at the 3' end of the intron around an unusual restriction fragment length polymorphism caused by deletion of a 1-kilobase fragment containing Alu family reiterated sequences. This clustering is unexpected in light of previous theories of rearrangement in Philadelphia chromosome-positive chronic myelogenous leukemia that would have predicted a random dispersion of breakpoints in the first intron in Philadelphia chromosome-positive ALL. The proximity of the translocation breakpoints to this constitutive deletion may indicate shared mechanisms of rearrangement or that such polymorphisms mark areas of the genome prone to recombination

  6. Variants forms of Philadelphia translocation in two patients with chronic myeloid leukemia

    International Nuclear Information System (INIS)

    Valent, A.; Zamecnikova, A.; Krizan, P.; Karlic, H.; Nowotny, H.

    1996-01-01

    During a 4-year period (December 1990-December 1994), among other diagnoses hundred cases of chronic myeloid leukemia (CML) were analyzed in our departments. We focused our attention on two cases with a variant form of Philadelphia translocation. Cytogenetic and molecular genetic studies were performed to resolve the status of BCR and ABL in the bone marrow or peripheral blood cells of the two CML patients with complex translocations involving chromosomes, 3, 9, 22 and 9, 12, 22 respectively. In the first case the presence of Ph chromosome was detected cytogenetically, BCR-ABL translocation was detected by Southern hybridization. In the second phase, only the PCR method showed BCR-ABL rearrangement. The second case, with a random variant form of Ph translocation, could be detected using different methods of clinical molecular genetics. (author)

  7. Staying in the Hood: Black Lesbian and Transgender Women and Identity Management in North Philadelphia.

    Science.gov (United States)

    Brooks, Siobhan

    2016-12-01

    The concept Don't Ask, Don't Tell regarding Black LGBT sexuality in Black communities has been an acceptable form of identity management for Black LGBT people. In other words, Black LGBT people are accepted as long as they are not vocal about their sexuality. However, this is changing with the issue of gay marriage, which is creating a space where Black LGBT people are more open about their gender identity and sexuality in heterosexual Black spaces. This new form of openness allows Black LGBT people to "stay in" their communities, as opposed to coming out. In this article I examine how Black LGBT women in North Philadelphia stay in their communities: being politically active regarding LGBT issues, disengaging from LGBT issues, passing, and educating straight Black people about issues affecting the Black LGBT community. I conclude with implications of staying in and intersectionality among Black heterosexual and LGBT women fighting for social change.

  8. [Hungarian Philadelphia negative chronic myeloproliferative neoplasia registry. Evaluation of the Polycythemia vera patients].

    Science.gov (United States)

    Dombi, Péter; Illés, Árpád; Demeter, Judit; Homor, Lajos; Simon, Zsófia; Kellner, Ádám; Karádi, Éva; Valasinyószki, Erika; Udvardy, Miklós; Egyed, Miklós

    2017-06-01

    Intruduction and aim: The Hungarian National Registry for Philadelphia chromosome negative myeloproliferative neoplasms has been developed. The aim of the recent study is to assess the clinical characteristics of Hungarian patients with polycythemia vera. Data of 351 JAK2 V617F and exon 12 mutation positive polycythemia vera patients were collected online from 15 haematology centres reporting epidemiologic, clinical characteristics, diagnostic tools, therapeutic interventions, thromboembolic complications, disease transformations. Vascular events prior to and after diagnosis were evaluated upon the Landolfi risk assessment scale. 116 thromboembolic events were reported in 106 PV patients prior to diagnosis and 152 occasions in 102 patients during follow-up. The frequency of major arterial events were significantly reduced (ppolycythemia vera. The Landolfi risk stratification was proven to be useful. Based on evaluated data, accuracy of diagnostic criteria and compliance to risk-adapted therapeutic guidelines are needed. Orv Hetil. 2017; 158(23): 901-909.

  9. Incidental detection of congenital Robertsonian translocation at diagnosis of Philadelphia chromosome-positive acute lymphocytic leukemia.

    Science.gov (United States)

    Yamaguchi, Tsukasa; Igarashi, Aiko; Kawamura, Machiko; Ozasa, Yuka; Yoshida, Masayuki; Kakihana, Kazuhiko; Sakamaki, Hisashi; Ohashi, Kazuteru

    2015-05-01

    A man in his early forties who had undergone 3 years of unsuccessful treatment for infertility due to oligospermia and asthenospermia developed fever and bone pain in December 20XX. He was subsequently diagnosed with acute lymphocytic leukemia. Conventional cytogenetic analysis revealed Robertsonian translocation (RT) with der(13;14)(q10;q10) in addition to the Philadelphia (Ph) chromosome. Dasatinib and prednisolone induced complete remission (CR) with disappearance of the Ph chromosome. However, RT persisted despite achieving CR. We speculate that RT is possibly congenital in our present case and might also have been responsible for the aforementioned infertility. Hematologists should be aware of the possibility that congenital chromosomal disorders might be found incidentally through diagnostic chromosome analysis for leukemia.

  10. Risk of Fall-Related Injury due to Adverse Weather Events, Philadelphia, Pennsylvania, 2006-2011.

    Science.gov (United States)

    Gevitz, Kathryn; Madera, Robbie; Newbern, Claire; Lojo, José; Johnson, Caroline C

    Following a surge in fall-related visits to local hospital emergency departments (EDs) after a severe ice storm, the Philadelphia Department of Public Health examined the association between inclement winter weather events and fall-related ED visits during a 5-year period. Using a standardized set of keywords, we identified fall-related injuries in ED chief complaint logs submitted as part of Philadelphia Department of Public Health's syndromic surveillance from December 2006 through March 2011. We compared days when falls exceeded the winter fall threshold (ie, "high-fall days") with control days within the same winter season. We then conducted matched case-control analysis to identify weather and patient characteristics related to increased fall-related ED visits. Fifteen high-fall days occurred during winter months in the 5-year period. In multivariable analysis, 18- to 64-year-olds were twice as likely to receive ED care for fall-related injuries on high-fall days than on control days. The crude odds of ED visits occurring from 7:00 am to 10:59 am were 70% higher on high-fall days vs control days. Snow was a predictor of a high-fall day: the adjusted odds of snow before a high-fall day as compared with snow before a control day was 13.4. The association between the number of fall-related ED visits and weather-related fall injuries, age, and timing suggests that many events occurred en route to work in the morning. Promoting work closures or delaying openings after severe winter weather would allow time for better snow or ice removal, and including "fall risk" in winter weather advisories might effectively warn morning commuters. Both strategies could help reduce the number of weather-related fall injuries.

  11. Adherence to Follow-up Recommendations Among Individuals in the Philadelphia Glaucoma Detection and Treatment Project.

    Science.gov (United States)

    Hark, Lisa A; Leiby, Benjamin E; Waisbourd, Michael; Myers, Jonathan S; Fudemberg, Scott J; Mantravadi, Anand V; Dai, Yang; Gilligan, John P; Resende, Arthur F; Katz, L Jay

    2017-08-01

    To evaluate rates of adherence to free follow-up eye exam appointments among participants in the Philadelphia Glaucoma Detection and Treatment Project. Ophthalmologists and testing equipment were brought directly to participants at risk for glaucoma at 43 community sites in Philadelphia. Those diagnosed with glaucoma-related pathology were recommended to return for follow-up to be reexamined on site. Rates of adherence and clinical and demographic risk factors for adherence were evaluated. Five hundred thirty-one participants were diagnosed with glaucoma-related conditions and recommended to attend community-based follow-up exams. Follow-up adherence rate was 61.2% (n=325/531). Significant factors associated with greater eye exam appointment adherence, based on our univariable analysis, included final diagnosis of glaucoma (risk ratio [RR]=1.33; 95% confidence interval [CI], 1.13-1.57), male sex (RR=1.19; 95% CI, 1.04-1.36), white race (RR=1.26; 95% CI, 1.08-1.48), age (RR=1.17; 95% CI, 1.00-1.37) recommendation for glaucoma medication (RR=1.52; 95% CI, 1.35-1.71), recommendation for laser peripheral iridotomy (RR=1.18; 95% CI, 1.02-1.35), diagnosis of age-related macular degeneration (RR=1.42; 95% CI, 1.13-1.77) and an increased intraocular pressure (>22 mm Hg in the worse eye) (RR=1.23; 95% CI, 1.06-1.42). On the basis of our multivariable model, diagnosis, sex, and recommended glaucoma medications were significantly associated with follow-up adherence. This study demonstrates that individuals living in underserved urban communities would take advantage of free eye exams in community sites and return for follow-up eye exams in these same settings. Future studies could investigate interventions to improve eye exam appointment adherence in community-based settings to detect glaucoma-eye conditions.

  12. Goal striving, goal attainment, and well-being: adapting and testing the self-concordance model in sport.

    Science.gov (United States)

    Smith, Alison; Ntoumanis, Nikos; Duda, Joan

    2007-12-01

    Grounded in self-determination theory (Deci & Ryan, 1985) and the self-concordance model (Sheldon & Elliot, 1999), this study examined the motivational processes underlying goal striving in sport as well as the role of perceived coach autonomy support in the goal process. Structural equation modeling with a sample of 210 British athletes showed that autonomous goal motives positively predicted effort, which, in turn, predicted goal attainment. Goal attainment was positively linked to need satisfaction, which, in turn, predicted psychological well-being. Effort and need satisfaction were found to mediate the associations between autonomous motives and goal attainment and between attainment and well-being, respectively. Controlled motives negatively predicted well-being, and coach autonomy support positively predicted both autonomous motives and need satisfaction. Associations of autonomous motives with effort were not reducible to goal difficulty, goal specificity, or goal efficacy. These findings support the self-concordance model as a framework for further research on goal setting in sport.

  13. White paper on science and technology, 1996. Striving to become a front-runner in research activity

    International Nuclear Information System (INIS)

    1996-01-01

    This is the first report on policy measures implemented with regard to the promotion of science and technology, in accordance with Article 8 of the Science and Technology Basic Law, which was enacted in November 1995. Parts 1 and 2 of this report discuss trends in a wide range of scientific and technological activities to help the reader understand the policy measures implemented to promote science and technology. Part 1, titled 'Striving to become a front-runner in research activity', attempts and analysis of the public's expectations and demands concerning science and technology; of the state of affairs at institutions engaged in R and D; and of the issues that require attention in the pursuit of future of research activity. In Part 2, various types of data are used to compare Japan's scientific and technological activities with those in other major nations. And, Part 3 contains Policies implemented for the promotion of science and technology. (G.K.)

  14. Impatience versus achievement strivings in the Type A pattern: Differential effects on students' health and academic achievement

    Science.gov (United States)

    Spence, Janet T.; Helmreich, Robert L.; Pred, Robert S.

    1987-01-01

    Psychometric analyses of college students' responses to the Jenkins Activity Survey, a self-report measure of the Type A behavior pattern, revealed the presence of two relatively independent factors. Based on these analyses, two scales, labeled Achievement Strivings (AS) and Impatience and Irritability (II), were developed. In two samples of male and female college students, scores on AS but not on II were found to be significantly correlated with grade point average. Responses to a health survey, on the other hand, indicated that frequency of physical complaints was significantly correlated with II but not with AS. These results suggest that there are two relatively independent factors in the Type A pattern that have differential effects on performance and health. Future research on the personality factors related to coronary heart disease and other disorders might more profitably focus on the syndrome reflected in the II scale than on the Type A pattern.

  15. Striving for quality use of medicines: how effective is Australia's ban on direct-to-consumer prescription medicine advertising?

    Science.gov (United States)

    Brown, Sonja

    2009-02-01

    The potential for both positive and negative effects arising from direct-to-consumer advertising of prescription medicines challenges health policymakers to develop regulatory schemes which selectively capture the positive aspects of the practice. Australia has dealt with this quandary by banning the practice, while New Zealand and the United States permit it. However, in recent times pharmaceutical companies have been increasingly successful in introducing promotional materials into the Australian market. This article demonstrates that the Australian ban is consistent with striving for the major policy goal of quality use of medicines, thus providing the basis for arguing that solutions to strengthen the ban against the identified threats ought to be implemented. Quality use of medicines can be most effectively achieved via the combined effect of the strengthened ban and the mimicking of the limited positive aspects of direct-to-consumer advertising by government provision of non-promotional information to consumers.

  16. Molecular diagnostic of the philadelphia chromosome; Diagnostico molecular del cromosoma filadelfia

    Energy Technology Data Exchange (ETDEWEB)

    Campos Rudin, M [Instituto de Investigaciones en Salud (INISA), Costa Rica (Costa Rica) and Escuela de Biologia; Cuenca Berger, P [Instituto de Investigaciones en Salud (INISA), Costa Rica (Costa Rica) and Escuela de Biologia; Gutierrez Espeleta, G [Instituto de Investigaciones en Salud (INISA), Costa Rica (Costa Rica) and Escuela de Biologia; Jimenez Cruz, G [Hospital Mexico, Costa Rica (Costa Rica). Seccion Hematologia; Montero Umana, C [Hospital Mexico, Costa Rica (Costa Rica). Seccion Hematologia; Vazquez Castillo, L [Hospital San Juan de Dios, Costa Rica (Costa Rica). Seccion de Hematologia; Ramon Ortiz, M [Hospital San Juan de Dios, Costa Rica (Costa Rica). Seccion de Hematologia

    1998-07-01

    The importance that has to confirm the presence or absence of the chromosome Philadelphia in the diagnostic and follow up of the patient affected with chronic myeloid leukemia and other leukemia. It is considered necessary to implement the molecular diagnostic in Costa Rica. They studied 32 patient affected by Chronic Myeloid Leukemia, 7 by other Myeloproliferative Chronic Disorders and 2 by Myelodysplastic Syndrome. It utilized the sound Trans probe-1 (Oncogene Science, Inc), which was marked with radioactivity ({sup 32}P) or chemiluminescence (digoxigenin). Of the 32 cases affected by L mc, in 28 it was possible to carry out the molecular analysis detecting the characteristic translocation of the chromosome Philadelphia among the Mbcr/c-ABL genes in 21 (75%) of the patients, in 7 (25%) the rearrangement was not found. In seven of the nine affected by other sufferings it was possible to obtain results, 3 that turned out to be positive for the rearrangement among Mbcr/c-ABL and 4 normal. In all the cases, they obtained results marking the sound with radioactivity. However, they tested the marks with digoxigenin in seven of the patients, as an methodological alternative for the laboratories that lacks the requirements to work with radiation. The results obtained were identical. (S. Grainger) [Spanish] La relevancia que tiene confirmar la presencia o ausencia del cromosoma Filadelfia en el diagnostico y seguimiento de los pacientes afectados con leucemia mieloide cronica y otras leucemias, se considero necesario implementar el diagnostico molecular en Costa Rica. Se estudiaron 32 pacientes afectados por Leucemia Mieloide Cronica, 7 por otros Desordenes Mieloproleferativos Cronicos y 2 por Sindromes Mielodisplasicos. Se utilizo la sonda Transprobe-1 (Oncogene Science, Inc), la cual fue marcada con radioactividad ({sup 32}P) o quimioluminiscencia (digoxigenina). De los 32 casos afectados por LMC, en 28 se logro realizar el analisis molecular detectandose la

  17. Understanding the independent influence of duty and achievement striving when predicting the relationship between conscientiousness and organizational cultural profiles and helping behaviors.

    Science.gov (United States)

    Moon, Henry; Livne, Ephrat; Marinova, Sophia

    2013-01-01

    The theory that 2 facets of the factor conscientiousness, duty and achievement striving, are related to self- or other-centered motives, is supported in 2 studies. In Study 1 (N = 204 undergraduates), the self-centered facet of achievement striving was found to be the most important predictor of attraction toward organizational cultures that were outcome-based, aggressive, and emphasized rewards. Achievement strivers were less attracted to supportive and decisive organizations. In Study 2 (N = 189 part-time MBA students) the other-centered facet of duty was found to be predictive of helping behaviors. Theoretical and practical implications are discussed.

  18. Muusikamaailm : Philadelphia Orkester Euroopas. Lloyd Webber La Scalasse? Algas Glyndebourne'i ooperifestival. Kolm kompositsioonipreemiat / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    2000-01-01

    Philadelphia Orchestra 100. aastapäevale pühendatud Euroopa turneest. Milano La Scala plaanitavast uuslavastuste sarjast "Mõistes XX sajandit ئ sisse elades XXI sajandisse", kus oleks kesksel kohal nelja elava helilooja lavateosed XX sajandist. Glyndebourne'i ooperifestivalist Inglismaal, A. Davise tegevusest. Kolme kompositsioonipreemia kätteandmisest : Salzburgi Osterfestspiele kompositsioonipreemia, Teatro Lirico Sperimentale kammerooperi konkursi preemia ja fondi Stiftung Christoph Delz kompositsioonikonkursi preemia

  19. A Case Study of the Philadelphia Sugar-Sweetened Beverage Tax Policymaking Process: Implications for Policy Development and Advocacy.

    Science.gov (United States)

    Purtle, Jonathan; Langellier, Brent; Lê-Scherban, Félice

    Policymakers are increasingly proposing sugar-sweetened beverage (SSB) taxes as an evidence-based strategy to reduce chronic disease risk; and local health departments (LHDs) are well-positioned to play a role in SSB policy development and advocacy. However, most SSB tax proposals fail to become law and limited empiric guidance exists to inform advocacy efforts. In June 2016, Philadelphia, Pennsylvania, passed an SSB tax. To identify features of the Philadelphia SSB tax policymaking process that contributed to the proposal's passage. Qualitative case study. Semistructured interviews were conducted with key informants closely involved with the policymaking process. Interviews were audio-recorded and transcribed. Local news media about the SSB tax proposal were analyzed to triangulate interview findings. Analysis was conducted in NVivo 10 using inductive qualitative content analysis. Philadelphia, Pennsylvania, during the SSB tax policymaking in process. Nine key informants (2 city councilpersons, 4 city agency officials, 1 community-based advocate, 1 news reporter, and 1 researcher). The Philadelphia SSB tax proposal was introduced with the explicit goal of financing universal prekindergarten and deliberately not framed as a health intervention. This framing shifted contentious debates about government involvement in individual behavior toward discussions about how to finance universal prekindergarten, a goal for which broad support existed. The LHD played an important role in communicating research evidence about potential health benefits of the SSB tax proposal at the end of the policymaking process. During local SSB tax policy development processes, LHD officials and other advocates should encourage policymakers to design SSB tax policies so that revenue is directed toward community investments for which broad public support exists. When communicating with policymakers and the public, LHDs should consider emphasizing how SSB tax revenue will be used in addition

  20. Prevalence, Disparities, and Trends in Obesity and Severe Obesity Among Students in the Philadelphia, Pennsylvania, School District, 2006–2010

    OpenAIRE

    Robbins, Jessica M.; Mallya, Giridhar; Polansky, Marcia; Schwarz, Donald F.

    2012-01-01

    Introduction Epidemic increases in obesity negatively affect the health of US children, individually and at the population level. Although surveillance of childhood obesity at the local level is challenging, height and weight data routinely collected by school districts are valuable and often underused public health resources. Methods We analyzed data from the School District of Philadelphia for 4 school years (2006–2007 through 2009–2010) to assess the prevalence of and trends in obesity and...

  1. Storing Empty Calories and Chronic Disease Risk: Snack-Food Products, Nutritive Content, and Manufacturers in Philadelphia Corner Stores

    OpenAIRE

    Lucan, Sean C.; Karpyn, Allison; Sherman, Sandy

    2010-01-01

    Corner stores are part of the urban food environment that may contribute to obesity and diet-related diseases, particularly for low-income and minority children. The snack foods available in corner stores may be a particularly important aspect of an urban child’s food environment. Unfortunately, there is little data on exactly what snack foods corner stores stock, or where these foods come from. We evaluated snack foods in 17 Philadelphia corner stores, located in three ethnically distinct, l...

  2. Characterization and Prognosis Significance of JAK2 (V617F), MPL, and CALR Mutations in Philadelphia-Negative Myeloproliferative Neoplasms

    OpenAIRE

    Singdong, Roongrudee; Siriboonpiputtana, Teerapong; Chareonsirisuthigul, Takol; Kongruang, Adcharee; Limsuwanachot, Nittaya; Sirirat, Tanasan; Chuncharunee, Suporn; Rerkamnuaychoke, Budsaba

    2016-01-01

    Background: The discovery of somatic acquired mutations of JAK2 (V617F) in Philadelphia-negative myeloproliferative neoplasms (Ph-negative MPNs) including polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF) has not only improved rational disease classification and prognostication but also brings new understanding insight into the pathogenesis of diseases. Dosage effects of the JAK2 (V617F) allelic burden in Ph-negative MPNs may partially influence clinical ...

  3. Low frequency of c-MPL gene mutations in Iranian patients with Philadelphia-negative myeloproliferative disorders.

    Science.gov (United States)

    Ghotaslou, A; Nadali, F; Chahardouli, B; Alizad Ghandforosh, N; Rostami, S H; Alimoghaddam, K; Ghavamzadeh, A

    2015-01-01

    Myeloproliferative disorders are a group of diseases characterized by increased proliferation of myeloid lineage. In addition to JAK2V617F mutation, several mutations in the c-MPL gene have been reported in patients with philadelphia-negative chronic myeloproliferative disorders that could be important in the pathogenesis of diseases. The aim of the present study was to investigate the frequency of c-MPL and JAK2V617F mutations in Iranian patients with Philadelphia-negativemyeloproliferative disorders. Peripheral blood samples were collected from 60 patients with Philadelphia-negative MPD) Subgroups ET and PMF) and 25 healthy subjects as control group. The mutation status of c-MPL and Jak2V617F were investigated by using Amplification-refractory mutation system (ARMS) and Allele-Specific PCR (AS-PCR), respectively. The results were confirmed by sequencing. Among 60 patients, 34 (56.6%) and 1(1.7%) had Jak2V617F and c-MPL mutation, respectively. Patients with Jak2V617F mutation had higher WBC counts and hemoglobin concentration than those without the mutation (p= 0.005, p=0.003). In addition, for all healthy subjects in control group, mutations were negative. The present study revealed that the c-MPL mutations unlike the Jak2V617F mutations are rare in Iranian patients with Ph-negative MPNs and the low mutation rate should be considered in the design of screening strategies of MPD patients.

  4. Ready or not: analysis of a no-notice mass vaccination field response in Philadelphia.

    Science.gov (United States)

    Caum, Jessica; Alles, Steven

    2013-12-01

    Local health departments typically rely on exercises to test preparedness capacity; however, pre-scripted drills often lack the sense of urgency that a real event would engender. No-notice, unscripted exercises that challenge staff to think critically under pressure may provide a mechanism for a more realistic assessment of preparedness capacity. The very active influenza season of 2012-13 presented the Public Health Preparedness Program at the Philadelphia Department of Public Health with the opportunity to conduct an influenza vaccination clinic at a local boarding school. Program leaders used this opportunity to design a no-notice exercise to test the ability of staff to effectively coordinate an emergency field response while simultaneously delivering a real public health intervention. On the day of the exercise, staff members were given 6 hours to plan and execute a vaccination clinic without any guidance from program leaders. Best practices observed during the exercise included: (1) early identification and mitigation of rate-limiting steps, and (2) successful implementation of a previously untested high-throughput vaccination model. Although the primary intent of the exercise was to assess the ability of staff to respond to a no-notice event, this vaccination clinic also functioned as a microcosm of a larger response, revealing several considerations related to vaccine ordering, staff resources, and throughput rates that have broader implications for public health responses to large-scale biological attacks or pandemics.

  5. The genetic architecture of pediatric cognitive abilities in the Philadelphia Neurodevelopmental Cohort

    Science.gov (United States)

    Robinson, Elise B.; Kirby, Andrew; Ruparel, Kosha; Yang, Jian; McGrath, Lauren; Anttila, Verneri; Neale, Benjamin M.; Merikangas, Kathleen; Lehner, Thomas; Sleiman, Patrick M.A.; Daly, Mark J.; Gur, Ruben; Gur, Raquel; Hakonarson, Hakon

    2014-01-01

    The objective of this analysis was to examine the genetic architecture of diverse cognitive abilities in children and adolescents, including the magnitude of common genetic effects and patterns of shared and unique genetic influences. Subjects included 3,689 members of the Philadelphia Neurodevelopmental Cohort, a general population sample of ages 8-21 years who completed an extensive battery of cognitive tests. We used genome-wide complex trait analysis (GCTA) to estimate the SNP-based heritability of each domain, as well as the genetic correlation between all domains that showed significant genetic influence. Several of the individual domains suggested strong influence of common genetic variants (e.g. reading ability, h2g=0.43, p=4e-06; emotion identification, h2g=0.36, p=1e-05; verbal memory, h2g=0.24, p=0.005). The genetic correlations highlighted trait domains that are candidates for joint interrogation in future genetic studies (e.g. language reasoning and spatial reasoning, r(g)=0.72, p=0.007). These results can be used to structure future genetic and neuropsychiatric investigations of diverse cognitive abilities. PMID:25023143

  6. The perils of healthcare workforce forecasting: a case study of the Philadelphia metropolitan area.

    Science.gov (United States)

    Smith, David Barton; Aaronson, William

    2003-01-01

    In 1996, a widely circulated and influential forecast for the Philadelphia Metropolitan Area stated that a decline in hospital and healthcare employment in the region would occur over the next five years. It also suggested that this decline would exacerbate the problem of an oversupply of nurses seeking hospital employment. The forecast reflected a regional leadership and expert consensus on the impact of the managed care transformation on workforce needs and was supported by short-term statistical trends in regional utilization and employment. Confounding these predictions was the fact that hospital and healthcare employment actually grew. By the end of 2001, hospitals in the region were experiencing problems in recruiting sufficient numbers of nurses, pharmacists, and technicians. The forecast failed to anticipate the impact of a strong regional economy on supply and underestimated the resilience of underlying forces that have driven the long-term growth in healthcare workforce demand. More effective ongoing monitoring can help moderate the fluctuation of workforce shortages and surpluses.

  7. Involvement of mast cells by the malignant process in patients with Philadelphia chromosome negative myeloproliferative neoplasms.

    Science.gov (United States)

    Wang, J; Ishii, T; Zhang, W; Sozer, S; Dai, Y; Mascarenhas, J; Najfeld, V; Zhao, Z J; Hoffman, R; Wisch, N; Xu, M

    2009-09-01

    The Philadelphia chromosome negative myeloproliferative neoplasms (MPNs) are clonal hematologic malignancies frequently characterized by a mutation in JAK2 (JAK2V617F). Peripheral blood (PB) CD34(+) cells from patients with polycythemia vera (PV) and primary myelofibrosis (PMF) generated in vitro significantly fewer mast cells (MCs) than normal PB CD34(+) cells. The numbers of MC progenitors assayed from MPN CD34(+) cells were, however, similar to that assayed from normal CD34(+) cells. A higher percentage of the cultured MPN MCs expressed FcvarepsilonRIalpha, CD63 and CD69 than normal MCs, suggesting that cultured MPN MCs are associated with an increased state of MC activation. Further analysis showed that a higher proportion of cultured PV and PMF MCs underwent apoptosis in vitro. By using JAK2V617F, MplW515L and chromosomal abnormalities as clonality markers, we showed that the malignant process involved MPN MCs. JAK2V617F-positive MC colonies were assayable from the PB CD34(+) cells of each of the 17 JAK2V617F positive MPN patients studied. Furthermore, erlotinib, a JAK2 inhibitor, was able to inhibit JAK2V617F-positive PV MC progenitor cells, indicating that malignant MC progenitor cells are a potential cellular target for such JAK2 inhibitor-directed therapy.

  8. Concurrent sexual partnerships among African American women in Philadelphia: results from a qualitative study.

    Science.gov (United States)

    Nunn, Amy; Dickman, Samuel; Cornwall, Alexandra; Kwakwa, Helena; Mayer, Kenneth H; Rana, Aadia; Rosengard, Cynthia

    2012-07-01

    African American women are disproportionately affected by HIV/AIDS. Concurrent sexual partnerships may contribute to racial disparities in HIV infection. Little is known about attitudes and practices related to concurrency among African American women, or the social, structural and behavioural factors influencing concurrency. We recruited 19 heterosexual African American women engaging in concurrent sexual partnerships from a public clinic in Philadelphia in 2009. We conducted interviews exploring social norms, attitudes and practices about concurrency, and the structural, social and behavioural factors influencing concurrent sexual partnerships, guided by grounded theory. Seventeen women reported one main and one or more non-main partners; two reported no main partners. Many women used condoms more frequently with non-main than main partners, noting they trust main partners more than non-main partners. Social factors included social normalisation of concurrency, inability to negotiate partners' concurrent partnerships, being unmarried, and not trusting partners. Lack of trust was the most commonly cited reason that women engaged in concurrent partnerships. Structural factors included economic dependence on partners, partners' dependence on women for economic support and incarceration that interrupted partnerships. Behavioural factors included alcohol and cocaine use. Social, structural and behavioural factors strongly influenced these African American women's concurrent sexual partnerships. Many HIV interventions disseminated by the CDC focus largely on behavioural factors and may fail to address the social and structural factors influencing African American women's sexual networks. Novel HIV prevention interventions that address the social determinants of African American women's HIV risks are urgently needed.

  9. Sex differences in brain and behavior in adolescence: Findings from the Philadelphia Neurodevelopmental Cohort.

    Science.gov (United States)

    Gur, Raquel E; Gur, Ruben C

    2016-11-01

    Sex differences in brain and behavior were investigated across the lifespan. Parameters include neurobehavioral measures linkable to neuroanatomic and neurophysiologic indicators of brain structure and function. Sexual differentiation of behavior has been related to organizational factors during sensitive periods of development, with adolescence and puberty gaining increased attention. Adolescence is a critical developmental period where transition to adulthood is impacted by multiple factors that can enhance vulnerability to brain dysfunction. Here we highlight sex differences in neurobehavioral measures in adolescence that are linked to brain function. We summarize neuroimaging studies examining brain structure, connectivity and perfusion, underscoring the relationship to sex differences in behavioral measures and commenting on hormonal findings. We focus on relevant data from the Philadelphia Neurodevelopmental Cohort (PNC), a community-based sample of nearly 10,000 clinically and neurocognitively phenotyped youths age 8-21 of whom 1600 have received multimodal neuroimaging. These data indicate early and pervasive sexual differentiation in neurocognitive measures that is linkable to brain parameters. We conclude by describing possible clinical implications. Copyright © 2016 Elsevier Ltd. All rights reserved.

  10. Proceedings of the 34th International Conference in High Energy Physics (ICHEP08), Philadelphia, PA, 2008

    International Nuclear Information System (INIS)

    Lockyer, Nigel S.; Smith, A.J. Stewart

    2008-01-01

    In 2004 a team from the University of Pennsylvania, Princeton University, and the Institute for Advanced Study proposed to host the 2008 International Conference on High Energy Physics (ICHEP) on the campus of the University of Pennsylvania in Philadelphia. The proposal was approved later that year by the C-11 committee of the International Union of Pure and Applied Physics. The Co-Chairs were Nigel S. Lockyer (U. Penn/TRIUMF) and A.J. Stewart Smith (Princeton); Joe Kroll of U. Penn served as Deputy Chair from 2007 on. Highlights of the proposal included 1. greatly increased participation of young scientists, women scientists, and graduate students 2. new emphasis on formal theory 3. increased focus on astrophysics and cosmology 4. large informal poster session (170 posters) in prime time 5. convenient, contiguous venues for all sessions and lodging 6. landmark locations for the reception and banquet. The conference program consisted of three days of parallel sessions and three days of plenary talks.

  11. Emissions inventories for urban airshed model application in the Philadelphia Aqcr (Air Quality Control Region)

    Energy Technology Data Exchange (ETDEWEB)

    1982-04-01

    This report documents the procedures used to develop emissions input required by the Urban Airshed photochemical oxidant model. Ambient air quality data were gathered as part of another effort during the summer of 1979 in Philadelphia to be used in the model validation effort. For 1979 and the 1987 projection year, ES compiled hour by hour emissions data for a representative weekday in the oxidant season. The pollutants inventoried are five categories of VOC required by the Airshed model, four categories of VOC defined in RAPS, NO, NO2, CO, SO2, and TSP. Point and area sources were considered with the highway vehicle portion of the inventory being subcontracted to DVRPC. County level area source data were allocated to a 502-cell grid system. Projections were made so that ozone air quality in 1987 could be investigated. ES developed annualized EIS/PandR data and data files containing temporal and VOC/NOx profiles in order to generate the data packets required by the Airshed model.

  12. Thromboembolism prophylaxis in patients with Philadelphia-negative myeloproliferative neoplasms-Clinical practice among Nordic specialists.

    Science.gov (United States)

    Bjerrum, Ole Weis; Samuelsson, Jan; Ghanima, Waleed; Kauppila, Marjut; Andersen, Christen Lykkegaard

    2018-05-01

    Patients with Philadelphia chromosome-negative myeloproliferative neoplasms (MPNs) have higher risks of developing thromboembolisms compared to the general population. International guidelines on the management of MPNs therefore include recommendations concerning thromboembolism prophylaxis. In clinical practice, strict adherence to guidelines may be challenging and dependent on factors such as physician experience, outpatient clinic setting, and access to therapy; however, no data exist on physician adherence or patient compliance to thromboembolism prophylaxis in MPNs. The Nordic Myeloproliferative Neoplasm Study Group (NMPN) performed a survey among Nordic hematology specialists with the aim of documenting the implementation of international recommendations in a region of Northern Europe with similar healthcare systems. The study showed that Nordic specialists managed their patients in accordance with international guidelines concerning medical intervention, but to a lesser degree regarding the management of additional cardiovascular risk factors. The survey also drew attention to the common clinical dilemma of combining antiaggregatory agents with vitamin K antagonists (VKA), or novel oral anticoagulants (NOAC), as well as phlebotomy limits in female polycythemia vera patients. The results of this study highlight the importance of considering all risk factors for thrombosis and an optimal collaboration with the primary healthcare sector. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  13. Imatinib Intolerance Is Associated With Blastic Phase Development in Philadelphia Chromosome-Positive Chronic Myeloid Leukemia.

    Science.gov (United States)

    Ángeles-Velázquez, Jorge Luis; Hurtado-Monroy, Rafael; Vargas-Viveros, Pablo; Carrillo-Muñoz, Silvia; Candelaria-Hernández, Myrna

    2016-08-01

    Over the past years, the survival of patients with Philadelphia-positive chronic myeloid leukemia (CML Ph(+)) has increased as a result of therapy with tyrosin kinase inhibitors (TKIs). Intolerance to TKIs has been described in approximately 20% of patients receiving treatment. We studied the incidence of imatinib intolerance in patients with CML Ph(+) and their outcome in our CML reference site, as there is no information about the evolution of patients intolerant to TKIs. A group of 86 patients with CML Ph(+) receiving imatinib monotherapy who abandoned treatment were the basis for this study. We present the trends of their disease evolution. The median of age at diagnosis was 42 years. Within a year, 19 (22%) of 86 patients developed imatinib intolerance, all of them with grade III or IV disease that required imatinib dose reduction or discontinuation. Of these patients, 16 (84%) of 19 developed transformation to blastic phase. The cumulative incidences of blastic phase development were 47% in the nonintolerant group and 84% in the intolerant group. There was a relative risk for those with imatinib intolerance to develop blastic phase of 1.78 (95% confidence interval, 1.28 to 2.42) (P treatment is available. Future research should to determine whether the origin of this evolution is really due to the intolerance itself or whether it is due to a more aggressive form of the disease, perhaps related to genetic transformation. Copyright © 2016 Elsevier Inc. All rights reserved.

  14. Abrupt evolution of Philadelphia chromosome-positive acute myeloid leukemia in myelodysplastic syndrome.

    Science.gov (United States)

    Fukunaga, Akiko; Sakoda, Hiroto; Iwamoto, Yoshihiro; Inano, Shojiro; Sueki, Yuki; Yanagida, Soshi; Arima, Nobuyoshi

    2013-03-01

    Myelodysplastic syndrome (MDS) is a clonal disorder arising from an alteration in multipotent stem cells, which lose the ability of normal proliferation and differentiation. Disease progression occurs in approximately 30% MDS cases. Specific chromosomal alterations seem responsible for each step in the evolution of acute myeloid leukemia (AML). Multiple genetic aberrations occur during the clonal evolution of MDS; however, few studies report the presence of the Philadelphia (Ph) chromosome. We report a rare case of Ph-positive AML, which evolved during the course of low-risk MDS. The patient, a 76-year-old man with mild leukocytopenia, was diagnosed with MDS, refractory neutropenia (RN). After 1.5 yr, his peripheral blood and bone marrow were suddenly occupied by immature basophils and myeloblasts, indicating the onset of AML. A bone marrow smear showed multilineage dysplasia, consistent with MDS evolution. Chromosomal analysis showed an additional t(9;22)(q34;q11) translocation. Because progression occurred concurrently with emergence of the Ph chromosome, we diagnosed this case as Ph-positive AML with basophilia arising from the clonal evolution of MDS. The patient was initially treated with nilotinib. A hematological response was soon achieved with disappearance of the Ph chromosome in the bone marrow. Emergence of Ph-positive AML in the course of low-risk MDS has rarely been reported. We report this case as a rare clinical course of MDS. © 2012 John Wiley & Sons A/S.

  15. Platelet indices in Philadelphia-negative chronic myeloproliferative neoplasms / Indicii plachetari de volum în neoplasmele mieloproliferative cronice Philadelphia-negative

    Directory of Open Access Journals (Sweden)

    Olteanu Ariela-Ligia

    2015-06-01

    Full Text Available Introducere: Neoplasmele mieloproliferative cronice cromozom Philadelphia negative (Ph-MPN -policitemia vera (PV, trombocitemia esenţială (TE şi mielofibroza primară (MP - sunt caracterizate de o rată mare de complicaţii trombotice, parţial date de activarea trombocitară. Trombocitele mari sunt mai active, cu o funcţie procoagulantă crescută şi au rol patogenic demonstrat în tromboza arterială şi venoasă. În studiul nostru am încercat să stabilim dacă indicii trombocitari (MPV, PDW, P-LCR, furnizaţi de analizoarele de hematologie în hemoleucograma completă, sunt modificaţi la pacienţii diagnosticaţi cu Ph-MPN comparativ cu subiecţii sănătoşi. Material şi metodă: Hemoleucograma, ce a inclus şi indicii trombocitari, a fost determinată la 102 pacienţi Ph- MPN şi la 102 subiecţi sănătoşi cu ajutorul analizorului de hematologie Sysmex XS 1000i (metoda impedanţei, iar testele biochimice (glucoza şi parametrii metabolismului lipidic, pe analizorul Architect c8000. Prezenţa mutaţiei JAK2 V617F, la pacienţii cu Ph-MPN, a fost evidenţiată prin tehnica ARMS-PCR. Rezultate: Indicii de volum plachetari (IVP măsuraţi prin metoda impedanţei, nu au fost semnificativ modificaţi la pacienţii cu Ph-MPN comparativ cu cei ai subiecţilor sănătoşi. Totuşi, am observat o moderată corelaţie între valoarea acestor indici şi prezenţa mutaţiei JAK2V617F, fără însă a se atinge o diferenţă semnificativă din punct de vedere statistic. IVP au fost crescuţi la micul subgrup de pacienţi trataţi cu anagrelide şi scăzuţi la cei trataţi cu simvastatin, comparativ cu pacienţii care nu au primit aceste terapii. Concluzii: Folosind metoda impedanţei în determinarea indicilor trombocitari, în studiul nostru nu am demonstrat o diferenţă semnificativă între valorile indicilor trombocitari la pacienţii cu Ph- MPN comparativ cu subiecţii sănătoşi. Sunt necesare studii ulterioare pentru a demonstra o

  16. How Philadelphia is Integrating Climate Science and Policy: Changing Capital Planning Processes and Developing Flood-Depth Tools

    Science.gov (United States)

    Bhat, C.; Dix, B.; Choate, A.; Wong, A.; Asam, S.; Schultz, P. A.

    2016-12-01

    Policy makers can implement more effective climate change adaptation programs if they are provided with two tools: accessible information on the impacts that they need to prepare for, and clear guidance on how to integrate climate change considerations into their work. This presentation will highlight recent and ongoing efforts at the City of Philadelphia to integrate climate science into their decision-making. These efforts include developing a climate change information visualization tool, climate change risk assessments across the city, and processes to integrate climate change into routine planning and budgeting practices. The goal of these efforts is to make climate change science highly targeted to decision maker needs, non-political, easily accessible, and actionable. While sea level rise inundation maps have been available to communities for years, the maps do not effectively communicate how the design of a building or a piece of infrastructure would need to be modified to protect it. The Philadelphia Flood Risk Viewer is an interactive planning tool that allows Philadelphia to identify projected depths of flooding for any location within the City, for a variety of sea level rise and storm surge scenarios. Users can also determine whether a location is located in a FEMA floodplain. By having access to information on the projected depth of flooding at a given location, the City can determine what flood protection measures may be effective, or even inform the long-term viability of developing a particular area. With an understanding of climate vulnerabilities, cities have the opportunity to make smart, climate-resilient investments with their capital budgets that will yield multiple benefits for years to come. Few, however, have established protocols for doing so. Philadelphia, with support from ICF, developed a guidance document that identifies recommendations for integrating climate change considerations throughout the Capital Program and capital budgeting

  17. The Electrical and Technology Curriculum of an Urban Charter High School and Its Impact for the Female in Academic and Trades Settings

    Science.gov (United States)

    Conway, Thomas Robert

    2010-01-01

    This study explores the impact of the electrical and technology curriculum of an urban charter high school in Philadelphia for the alumnae of the school. The study found a positive impact that empowered the alumnae to face gender and racial discrimination in their apprenticeship program. It also found a positive impact for alumnae that are not…

  18. Ethnicity, goal striving and schizophrenia: a case-control study of three ethnic groups in the United Kingdom.

    Science.gov (United States)

    Mallett, Rosemarie; Leff, Julian; Bhugra, Dinesh; Takei, Nori; Corridan, Bryan

    2004-12-01

    The need to achieve is common to all societies, and failure to do so may have a highly detrimental psychological impact. For those on the margins of mainstream society, especially migrants or descendants of migrants, the impact of failed or poor achievements may increase their vulnerability to mental illness. In a prospective study of schizophrenia in three ethnic groups (White, Indian and African-Caribbean) we studied the impact of goal striving and investigated whether the gap between the poor achievement and the high aspirations of members of some minority ethnic groups was potentially a factor contributing to the development of the illness. The patients and age- and sex-matched controls from their respective communities were asked to rate their perceived current levels of achievement and their past and future expectations in five domains--social standing, housing, education, employment and financial status on a 10-point scale. The control subjects from the three ethnic groups scored similarly in most areas, supporting the validity of inter-ethnic comparisons. The gap between achievement and expectations did not appear to cause high disappointment levels in any group, and in fact only in the domain of housing did the African-Caribbean patients assess their current achievement as being significantly lower than that of their matched controls. Poor housing conditions may be one of the risk factors contributing to the high incidence of schizophrenia in African-Caribbeans.

  19. The $2000 Electric Powertrain Option-1 Program. Final technical report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-06-01

    This report describes the tasks accomplished as part of Northrop Grumman's TRP $2000 Electric Powertrain Option-1 program. Northrop Grumman has strived to achieve technology advances and development considered as high priority to the success of future electric vehicles. Northrop Grumman has achieved the intent of the program by taking several steps toward reducing the cost of the electric vehicle powertrain, demonstrating technologies in the form of hardware and introducing enhancements into production that are consistent with the needs of the market.

  20. Striving for Experiential Resonance

    DEFF Research Database (Denmark)

    Aagaard, Jesper

    2018-01-01

    -tinction between a hermeneutics of suspicion and a hermeneutics of faith, this article sketches out two possible answers. It first presents a critical approach that exposes hidden truths to educate and emancipate its readers. The concept of ‘critique’ has recently come under scrutiny, however, with postcritical...

  1. Striving for Excellence

    DEFF Research Database (Denmark)

    Hattke, Fabian; Blaschke, Steffen

    2015-01-01

    Purpose: - The purpose of this paper is to evaluate the influence of top management team diversity on academic excellence in universities. Academic excellence is conceptualized as successfully gaining funds for inter-organizational research collaborations, interdisciplinary graduate schools......, and high ranked scientific reputation. Design/methodology/approach: -The study applies upper echelon theory to universities. Three hypotheses are developed: 1) (Overall) top management team heterogeneity is positively associated with successful funding of excellence clusters, 2) (Overall) top management...... no significant effects. Besides top management team composition, we find that a high number of faculties and a broad inclusion of internal status groups (students, tenured faculty, academic and administrative staff) and external stakeholders in decision making processes may enhance academic excellence...

  2. Concentration of Tobacco Advertisements at SNAP and WIC Stores, Philadelphia, Pennsylvania, 2012

    Science.gov (United States)

    Chilton, Mariana; Zhao, Qian-Wei; Szymkowiak, Dorota; Coffman, Ryan; Mallya, Giridhar

    2015-01-01

    Introduction Tobacco advertising is widespread in urban areas with racial/ethnic minority and low-income households that participate in nutrition assistance programs. Tobacco sales and advertising are linked to smoking behavior, which may complicate matters for low-income families struggling with disparate health risks relating to nutrition and chronic disease. We investigated the relationship between the amount and type of tobacco advertisements on tobacco outlets and the outlet type and location. Methods By using field visits and online images, we inspected all licensed tobacco retail outlets in Philadelphia (N = 4,639). Point pattern analyses were used to identify significant clustering of tobacco outlets and outlets with exterior tobacco advertisements. Logistic regression was used to analyze the relationship between the outlet’s acceptance of Supplemental Nutrition Assistance Program (SNAP) and Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) and the presence of tobacco advertisements. Results Tobacco outlets with exterior tobacco advertisements were significantly clustered in several high-poverty areas. Controlling for racial/ethnic and income composition and land use, SNAP and WIC vendors were significantly more likely to have exterior (SNAP odds ratio [OR], 2.11; WIC OR, 1.59) and interior (SNAP OR, 3.43; WIC OR, 1.69) tobacco advertisements than other types of tobacco outlets. Conclusion Tobacco advertising is widespread at retail outlets, particularly in low-income and racial/ethnic minority neighborhoods. Policy makers may be able to mitigate the effects of this disparate exposure through tobacco retail licensing, local sign control rules, and SNAP and WIC authorization. PMID:25654220

  3. Green Infrastructure Simulation and Optimization to Achieve Combined Sewer Overflow Reductions in Philadelphia's Mill Creek Sewershed

    Science.gov (United States)

    Cohen, J. S.; McGarity, A. E.

    2017-12-01

    The ability for mass deployment of green stormwater infrastructure (GSI) to intercept significant amounts of urban runoff has the potential to reduce the frequency of a city's combined sewer overflows (CSOs). This study was performed to aid in the Overbrook Environmental Education Center's vision of applying this concept to create a Green Commercial Corridor in Philadelphia's Overbrook Neighborhood, which lies in the Mill Creek Sewershed. In an attempt to further implement physical and social reality into previous work using simulation-optimization techniques to produce GSI deployment strategies (McGarity, et al., 2016), this study's models incorporated land use types and a specific neighborhood in the sewershed. The low impact development (LID) feature in EPA's Storm Water Management Model (SWMM) was used to simulate various geographic configurations of GSI in Overbrook. The results from these simulations were used to obtain formulas describing the annual CSO reduction in the sewershed based on the deployed GSI practices. These non-linear hydrologic response formulas were then implemented into the Storm Water Investment Strategy Evaluation (StormWISE) model (McGarity, 2012), a constrained optimization model used to develop optimal stormwater management practices on the watershed scale. By saturating the avenue with GSI, not only will CSOs from the sewershed into the Schuylkill River be reduced, but ancillary social and economic benefits of GSI will also be achieved. The effectiveness of these ancillary benefits changes based on the type of GSI practice and the type of land use in which the GSI is implemented. Thus, the simulation and optimization processes were repeated while delimiting GSI deployment by land use (residential, commercial, industrial, and transportation). The results give a GSI deployment strategy that achieves desired annual CSO reductions at a minimum cost based on the locations of tree trenches, rain gardens, and rain barrels in specified land

  4. Current Concepts in Pediatric Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

    Science.gov (United States)

    Bernt, Kathrin M.; Hunger, Stephen P.

    2014-01-01

    The t(9;22)(q34;q11) or Philadelphia chromosome creates a BCR–ABL1 fusion gene encoding for a chimeric BCR–ABL1 protein. It is present in 3–4% of pediatric acute lymphoblastic leukemia (Ph+ ALL), and about 25% of adult ALL cases. Prior to the advent of tyrosine kinase inhibitors (TKI), Ph+ ALL was associated with a very poor prognosis despite the use of intensive chemotherapy and frequently hematopoietic stem-cell transplantation (HSCT) in first remission. The development of TKIs revolutionized the therapy of Ph+ ALL. Addition of the first generation ABL1 class TKI imatinib to intensive chemotherapy dramatically increased the survival for children with Ph+ ALL and established that many patients can be cured without HSCT. In parallel, the mechanistic understanding of Ph+ ALL expanded exponentially through careful mapping of pathways downstream of BCR–ABL1, the discovery of mutations in master regulators of B-cell development such as IKZF1 (Ikaros), PAX5, and early B-cell factor (EBF), the recognition of the complex clonal architecture of Ph+ ALL, and the delineation of genomic, epigenetic, and signaling abnormalities contributing to relapse and resistance. Still, many important basic and clinical questions remain unanswered. Current clinical trials are testing second generation TKIs in patients with newly diagnosed Ph+ ALL. Neither the optimal duration of therapy nor the optimal chemotherapy backbone are currently defined. The role of HSCT in first remission and post-transplant TKI therapy also require further study. In addition, it will be crucial to continue to dig deeper into understanding Ph+ ALL at a mechanistic level, and translate findings into complementary targeted approaches. Expanding targeted therapies hold great promise to decrease toxicity and improve survival in this high-risk disease, which provides a paradigm for how targeted therapies can be incorporated into treatment of other high-risk leukemias. PMID:24724051

  5. Mechatronics Engineers’ Perception of Code Mixing: Philadelphia University and Hashemite University as a Case Study

    Directory of Open Access Journals (Sweden)

    Mustafa Al-Khawaldeh

    2016-11-01

    Full Text Available It has recently been widely recognized that code-switching is prevalent in Jordanians' daily conversation in various situations such as home, cafés, universities, restaurants and clubs. Abalhassan and Alshalawi (2000: 183 made a very related observation on code switching behavior among Arab speakers of English that “without exception, all respondents switched into English to some degree”. This could be referred to the increase number of technological advances and people travelling across countries for pleasure or for pursuing further education. In light of this observation, the crucial role of language in people's life, ambivalent attitudes towards code-switching (Akbar, 2007, the dearth of research in this area, such a present study is required to explore Jordanian university students’ and instructors’ perceptions of code-switching in their daily classroom conversation and its expected impact on their language proficiency. In particular, it investigates the factors leading them to code mix and their underlying attitudes towards its expected future impact on their language proficiency. To the best knowledge of the present researcher, this study is the first of its kind in Jordan. Data was collected via semi-structured interviews and a questionnaire from 70 university students and 30 instructors from both Philadelphia University and the Hashemite University. Data revealed that code mixing between English and Arabic is a common phenomenon in lectures they have attended in their academic institutions. The participants also show that they find code mixing fascinating and believe that though code switching might have a positive impact on their learning as it helps them better understand the topic. The instructors revealed that code mixing fulfill a set of functions that serve the educational process.

  6. Effects of Bosutinib Treatment on Renal Function in Patients With Philadelphia Chromosome-Positive Leukemias.

    Science.gov (United States)

    Cortes, Jorge E; Gambacorti-Passerini, Carlo; Kim, Dong-Wook; Kantarjian, Hagop M; Lipton, Jeff H; Lahoti, Amit; Talpaz, Moshe; Matczak, Ewa; Barry, Elly; Leip, Eric; Brümmendorf, Tim H; Khoury, H Jean

    2017-10-01

    The purpose of the study was to assess renal function in patients with Philadelphia chromosome-positive leukemias receiving bosutinib or imatinib. Patients received first-line bosutinib (n = 248) or imatinib (n = 251; phase III trial), or second-line or later bosutinib (phase I/II trial; n = 570). Adverse events (AEs) and changes from baseline in estimated glomerular filtration rate (eGFR) and serum creatinine were assessed. Time from the last patient's first dose to data cutoff was ≥ 48 months. Renal AEs were reported in 73/570 patients (13%) receiving second-line or later bosutinib, and in 22/248 (9%) and 16/251 (6%) receiving first-line bosutinib and imatinib, respectively. eGFR in patients receiving bosutinib declined over time with more patients developing Grade ≥ 3b eGFR (570, 24%) compared with first-line bosutinib (26/248, 10%) and imatinib (25/251, 10%); time to Grade ≥ 3b eGFR was shortest with second-line or later bosutinib. Similar proportions of patients receiving second-line or later bosutinib (74/139, 53%), first-line bosutinib (15/26, 58%), and first-line imatinib (15/25, 60%) improved to ≥ 45 mL/min/1.73 m 2 eGFR as of the last follow-up. In a regression analysis, first-line treatment with bosutinib versus imatinib was not a significant predictor of Grade ≥ 3b eGFR. Long-term bosutinib treatment is associated with an apparently reversible decline in renal function with frequency and characteristics similar to renal decline observed with long-term imatinib treatment. Patients with risk factors for Grade ≥ 3b eGFR should be monitored closely. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. Philadelphia chromosome-negative classical myeloproliferative neoplasms: revised management recommendations from European LeukemiaNet.

    Science.gov (United States)

    Barbui, Tiziano; Tefferi, Ayalew; Vannucchi, Alessandro M; Passamonti, Francesco; Silver, Richard T; Hoffman, Ronald; Verstovsek, Srdan; Mesa, Ruben; Kiladjian, Jean-Jacques; Hehlmann, Rȕdiger; Reiter, Andreas; Cervantes, Francisco; Harrison, Claire; Mc Mullin, Mary Frances; Hasselbalch, Hans Carl; Koschmieder, Steffen; Marchetti, Monia; Bacigalupo, Andrea; Finazzi, Guido; Kroeger, Nicolaus; Griesshammer, Martin; Birgegard, Gunnar; Barosi, Giovanni

    2018-05-01

    This document updates the recommendations on the management of Philadelphia chromosome-negative myeloproliferative neoplasms (Ph-neg MPNs) published in 2011 by the European LeukemiaNet (ELN) consortium. Recommendations were produced by multiple-step formalized procedures of group discussion. A critical appraisal of evidence by using Grades of Recommendation, Assessment, Development and Evaluation (GRADE) methodology was performed in the areas where at least one randomized clinical trial was published. Seven randomized controlled trials provided the evidence base; earlier phase trials also informed recommendation development. Key differences from the 2011 diagnostic recommendations included: lower threshold values for hemoglobin and hematocrit and bone marrow examination for diagnosis of polycythemia vera (PV), according to the revised WHO criteria; the search for complementary clonal markers, such as ASXL1, EZH2, IDH1/IDH2, and SRSF2 for the diagnosis of myelofibrosis (MF) in patients who test negative for JAK2V617, CALR or MPL driver mutations. Regarding key differences of therapy recommendations, both recombinant interferon alpha and the JAK1/JAK2 inhibitor ruxolitinib are recommended as second-line therapies for PV patients who are intolerant or have inadequate response to hydroxyurea. Ruxolitinib is recommended as first-line approach for MF-associated splenomegaly in patients with intermediate-2 or high-risk disease; in case of intermediate-1 disease, ruxolitinib is recommended in highly symptomatic splenomegaly. Allogeneic stem cell transplantation is recommended for transplant-eligible MF patients with high or intermediate-2 risk score. Allogeneic stem cell transplantation is also recommended for transplant-eligible MF patients with intermediate-1 risk score who present with either refractory, transfusion-dependent anemia, blasts in peripheral blood > 2%, adverse cytogenetics, or high-risk mutations. In these situations, the transplant procedure should be

  8. Philadelphia-negative classical myeloproliferative neoplasms: critical concepts and management recommendations from European LeukemiaNet.

    Science.gov (United States)

    Barbui, Tiziano; Barosi, Giovanni; Birgegard, Gunnar; Cervantes, Francisco; Finazzi, Guido; Griesshammer, Martin; Harrison, Claire; Hasselbalch, Hans Carl; Hehlmann, Rudiger; Hoffman, Ronald; Kiladjian, Jean-Jacques; Kröger, Nicolaus; Mesa, Ruben; McMullin, Mary F; Pardanani, Animesh; Passamonti, Francesco; Vannucchi, Alessandro M; Reiter, Andreas; Silver, Richard T; Verstovsek, Srdan; Tefferi, Ayalew

    2011-02-20

    We present a review of critical concepts and produce recommendations on the management of Philadelphia-negative classical myeloproliferative neoplasms, including monitoring, response definition, first- and second-line therapy, and therapy for special issues. Key questions were selected according the criterion of clinical relevance. Statements were produced using a Delphi process, and two consensus conferences involving a panel of 21 experts appointed by the European LeukemiaNet (ELN) were convened. Patients with polycythemia vera (PV) and essential thrombocythemia (ET) should be defined as high risk if age is greater than 60 years or there is a history of previous thrombosis. Risk stratification in primary myelofibrosis (PMF) should start with the International Prognostic Scoring System (IPSS) for newly diagnosed patients and dynamic IPSS for patients being seen during their disease course, with the addition of cytogenetics evaluation and transfusion status. High-risk patients with PV should be managed with phlebotomy, low-dose aspirin, and cytoreduction, with either hydroxyurea or interferon at any age. High-risk patients with ET should be managed with cytoreduction, using hydroxyurea at any age. Monitoring response in PV and ET should use the ELN clinicohematologic criteria. Corticosteroids, androgens, erythropoiesis-stimulating agents, and immunomodulators are recommended to treat anemia of PMF, whereas hydroxyurea is the first-line treatment of PMF-associated splenomegaly. Indications for splenectomy include symptomatic portal hypertension, drug-refractory painful splenomegaly, and frequent RBC transfusions. The risk of allogeneic stem-cell transplantation-related complications is justified in transplantation-eligible patients whose median survival time is expected to be less than 5 years.

  9. Acute, fatal Sarcocystis calchasi-associated hepatitis in Roller pigeons (Columba livia f. dom.) at Philadelphia Zoo.

    Science.gov (United States)

    Trupkiewicz, J G; Calero-Bernal, R; Verma, S K; Mowery, J; Davison, S; Habecker, P; Georoff, T A; Ialeggio, D M; Dubey, J P

    2016-01-30

    Four Roller pigeons (Columba livia f. dom.) at the Philadelphia Zoo died suddenly. Necropsy examination revealed macroscopic hepatitis. Microscopically, the predominant lesions were in liver, characterized with necrosis and mixed cell inflammatory response. Sarcocystis calchasi-like schizonts and free merozoites were identified in liver. Transmission electron microscopy confirmed that schizonts were in hepatocytes. A few schizonts were in spleen. PCR using S. calchasi-specific primers confirmed the diagnosis. Neither lesions nor protozoa were found in brain and muscles. This is the first report of acute visceral S. calchasi-associated sarcocystosis in naturally infected avian hosts. Published by Elsevier B.V.

  10. Otto Rank, the Rankian circle in Philadelphia, and the origins of Carl Rogers' person-centered psychotherapy.

    Science.gov (United States)

    deCarvalho, R J

    1999-05-01

    Otto Rank's will therapy helped shape the ideas and techniques of relationship therapy developed by the Philadelphia social workers Jessie Taft, Virginia Robinson, and Frederick Allen in the 1930s. Rank's work and these ideas and techniques in turn strongly influenced the formulation of Carl Rogers' person-centered psychotherapy. This article compares and contrasts will, relationship, and person-centered approaches to psychotherapy and discusses the social factors--primarily the professional conflicts between a male-dominated psychiatry and female social workers over the independent practice of psychotherapy--that were crucial in the dissemination of Rank's psychological thought and the early popularity of Rogers.

  11. Variant Philadelphia translocations with different breakpoints in six chronic myeloid leukemia patients

    Directory of Open Access Journals (Sweden)

    Dilhan Kuru

    2011-09-01

    Full Text Available Objective: The Philadelphia (Ph chromosome, consisting of the t(9;22(q34;q11 translocation, is observed in ~90% of patients with chronic myeloid leukemia (CML. Variant Ph translocations are observed in 5%-10% of CML patients. In variant translocations 3 and possibly more chromosomes are involved. Herein we report 6 CML patients with variant Ph translocations.Materials and Methods: Bone marrow samples were examined using conventional cytogenetic meth ods. Fluorescence in situ hybridization (FISH with whole-chromosome paints and BCR-ABL 1D probes were used to confirm and/or complement the findings, and identify rearrangements beyond the resolution of conventional cytogenetic methods. Results: Variant Ph translocations in the 6 patients were as follows: t(7;22(p22;q11, t(9;22;15(q34;q11;q22, t(15;22(p11;q11, t(1;9;22;3(q24;q34;q11;q21, t(12;22(p13;q11, and t(4;8;9;22(q11;q13;q34;q11.Conclusion: Among the patients, 3 had simple and 3 had complex variant Ph translocations. Two of the presented cases had variant Ph chromosomes not previously described, 1 of which had a new complex Ph translocation involving chromosomes 1, 3, 9, 22, and t(1;9;22;3(q24;q34;q11;q21 apart from a clone with a classical Ph, and the other case had variant Ph translocation with chromosomes 4, 8, 9, and 22, and t(4;8;9;22(q11;q13;q34;q11 full complex translocation. Number of studies reported that some patients with variant Ph translocation were poor responders to imatinib. All of our patients with variant Ph translocations had suboptimal responses to imatinib, denoting a poor prognosis also. Variant Ph translocations may be important as they are associated with prognosis and therapy for CML patients.

  12. Challenges in striving to simultaneously achieve multiple resource allocation goals: the pan-Canadian Oncology Drug Review (pCODR) example.

    Science.gov (United States)

    McDonald, Heather; Charles, Cathy; Elit, Laurie; Gafni, Amiram

    2016-01-01

    The pan-Canadian Oncology Drug Review (pCODR) makes recommendations to Canada's provinces and territories (except Quebec) to guide their cancer drug funding decisions. The objective of this paper is to explore, using an economic perspective and the pCODR as an example, the challenges associated with striving to simultaneously achieve the goals of maximizing health benefits with available resources and improving access to a more consistent standard of care across Canada. The first challenge concerns how to interpret the goals in order to determine how resources should be allocated to achieve each goal. The second challenge relates to whether, if pursued simultaneously, both goals can be achieved to the same extent that each goal could have been achieved alone with the same available resources. Regarding the first challenge, we illustrate that, due to a lack of definitional clarity, it is difficult to determine exactly how resources should be allocated in order to achieve the goal of improving access to a more consistent standard of care across Canada. Regarding the second challenge, we illustrate that choosing to strive for both of the pCODR goals simultaneously will likely be associated with tradeoffs in the extent to which one or both goals can be achieved (relative to what could have been achieved for each goal alone with the same available resources). We suggest that, if the pCODR and the provincial drug plan decision-makers it supports want to strive for both goals simultaneously, they must prioritize the goals and explicitly identify the tradeoffs associated with the prioritization. This will ensure that the consequences of striving to simultaneously achieve both goals are explicit, transparent, and predictable for provincial drug plan decision-makers, physicians, patients, caregivers, and society as a whole.

  13. Striving to be prepared for the painful: Management strategies following a family member's diagnosis of advanced cancer

    Directory of Open Access Journals (Sweden)

    Hedberg Berith

    2011-10-01

    Full Text Available Abstract Background Cancer has consequences not only for the sick person but also for those who have a close relationship with that person. Greater knowledge about how family members manage the situation in the period immediately following the diagnosis means greater opportunity to provide the best possible support for the family. The purpose of this study was to explore management strategies that family members use when the patient is in the early stage of treatment for advanced cancer. Methods Twenty family members of cancer patients were included in the study shortly after the diagnosis. The patients had been diagnosed 8-14 weeks earlier with advanced lung cancer or gastrointestinal cancer. The data were collected in interviews with family members and subjected to qualitative latent content analysis. Through the identification of similarities and dissimilarities in the units of meaning, abstraction into codes and sub-themes became possible. The sub-themes were then brought together in one overarching theme. Results The overall function of management strategies is expressed in the theme Striving to be prepared for the painful. The family members prepare themselves mentally for the anticipated tragedy. Family relationships become increasingly important, and family members want to spend all their time together. They try to banish thoughts of the impending death and want to live as normal a life as possible. It becomes important to family members to live in the present and save their energy for the time when they will need it the most. How participants handle their worries, anxiety and sadness can be categorized into seven sub-themes or management strategies: Making things easier in everyday life, Banishing thoughts about the approaching loss, Living in the present, Adjusting to the sick person's situation, Distracting oneself by being with others, Shielding the family from grief, and Attempting to maintain hope. Conclusions The findings revealed

  14. The effect of Philadelphia and Pennsylvania Clean Indoor Air Act on food services and drinking places sales and numbers, 1998-2011.

    Science.gov (United States)

    Ma, Zhen-Qiang; Fisher, Monica A

    2013-11-27

    Philadelphia enacted its Clean Indoor Air Act (CIAA) nearly 2 years before the statewide CIAA. In this study, we assessed the economic impact of CIAAs on 4 types of food services and drinking places and addressed the predominant limitation of previous pre-post ban studies, namely the lack of control for confounders and changes in secular trends over time. We analyzed data from Pennsylvania Department of Revenue Quarterly 1998-2011 taxable county-level revenue sales and number of food services and drinking places. Region-specific and type-specific adjusted sales and number of food services and drinking places accounted for consumer spending as a general economic indicator. Segmented regression analysis of interrupted time-series methodology assessed changes in trend and level. Pennsylvania CIAA had no significant effect on adjusted sales or numbers except for an increase in sales in Philadelphia for limited-service eating places and in the surrounding 4 counties for special food services. Philadelphia CIAA was associated with an increase in adjusted numbers of full-service restaurants in Philadelphia and the rest of the state, special food services in Philadelphia, and drinking places in the rest of the state, and a decrease in the number of special food services in the surrounding counties. Philadelphia CIAA had no significant effect on adjusted sales except for an increase in special food services in the rest of the state. Overall, CIAAs had no negative business-related impact and, for the most part, suggest a positive impact on restaurant sales and numbers. Our results provide further support for comprehensive CIAA ordinance for restaurants.

  15. A comparison of the prevalence of lead-contaminated imported Chinese ceramic dinnerware purchased inside versus outside Philadelphia's Chinatown.

    Science.gov (United States)

    Gilmore, Thomas; O'Malley, Gerald F; Lau, Wayne Bond; Vann, David R; Bromberg, Adam; Martin, Aaron; Gibbons, Andrea; Rimmer, Evan

    2013-03-01

    Lead-contaminated ceramics can be a clinically significant source of lead poisoning, with the potential to cause illness in children and adults; one death in a child has been described. We hypothesized that the prevalence of lead-contaminated ceramics would be higher within Chinatown versus outside of Chinatown. The study was a prospective observational cross-sectional study. Two areas were defined geographically as being within and outside of Philadelphia's Chinatown, and a predefined number of items were purchased in each area. Each item was screened for lead utilizing a colorimetric testing swab. Positive items were leached for lead using the ASTM C738-94 protocol for lead level quantification. The primary outcome was the prevalence of ceramics not compliant with the FDA standard for leachable lead within and outside of Philadelphia's Chinatown. A total of 132 items were purchased, 46 outside of and 86 within Chinatown. More lead-positive items originated within Chinatown than outside of Chinatown [five positive items, 5.8 % prevalence within Chinatown (95 % confidence interval, CI, 2.5-12.9 %), and zero positive, 0 % prevalence outside of Chinatown (95 % CI 0-7.5 %)]. However, this difference was not found to be statistically significant (P = 0.1624). The leachable lead-positive items were up to 40-fold the acceptable FDA levels. Testing a larger number of items may demonstrate a significant source of lead exposure.

  16. Validation of the Children's Hospital of Philadelphia Retinopathy of Prematurity (CHOP ROP) Model.

    Science.gov (United States)

    Binenbaum, Gil; Ying, Gui-Shuang; Tomlinson, Lauren A

    2017-08-01

    The Children's Hospital of Philadelphia Retinopathy of Prematurity (CHOP ROP) model uses birth weight (BW), gestational age at birth (GA), and weight gain rate to predict the risk of severe retinopathy of prematurity (ROP). In a model development study, it predicted all infants requiring treatment, while greatly reducing the number of examinations compared with current screening guidelines. To validate the CHOP ROP model in a multicenter cohort that is large enough to obtain a precise estimate of the model's sensitivity for treatment-requiring ROP. This investigation was a secondary analysis of data from the Postnatal Growth and Retinopathy of Prematurity (G-ROP) Study. The setting was 30 hospitals in the United States and Canada between January 1, 2006, and June 30, 2012. The dates of analysis were September 28 to October 5, 2015. Participants were premature infants at risk for ROP with a known ROP outcome. Sensitivity for Early Treatment of Retinopathy of Prematurity type 1 ROP and potential reduction in the number of infants requiring examinations. In the primary analysis, the CHOP ROP model was applied weekly to predict the risk of ROP. If the risk was above a cut-point level (high risk), examinations were indicated, while low-risk infants received no examinations. In a secondary analysis, low-risk infants received fewer examinations rather than no examinations. Participants included 7483 premature infants at risk for ROP with a known ROP outcome. Their median BW was 1070 g (range, 310-3000 g), and their median GA was 28 weeks (range, 22-35 weeks). Among them, 3575 (47.8%) were female, and their race/ethnicity was 3615 white (48.3%), 2310 black (30.9%), 233 Asian (3.1%), 93 Pacific Islander (1.2%), and 40 American Indian/Alaskan native (0.5%). The original CHOP ROP model correctly predicted 452 of 459 infants who developed type 1 ROP (sensitivity, 98.5%; 95% CI, 96.9%-99.3%), reducing the number of infants requiring examinations by 34.3% if only high

  17. Electricity Theory

    International Nuclear Information System (INIS)

    Gong, Ha Soung

    2006-12-01

    The text book composed of five parts, which are summary of this book, arrangement of electricity theory including electricity nad magnetism, a direct current, and alternating current. It has two dictionary electricity terms for a synonym. The last is an appendix. It is for preparing for test of officer, electricity engineer and fire fighting engineer.

  18. Electric vehicles, magnetic levitation and superconductive levitation in Japan

    International Nuclear Information System (INIS)

    Wyczalek, F.A.

    1988-01-01

    This is a technological assessment of electric automotive vehicles, high speed magnetic levitation trains and hyperspeed superconductive magnetic levitation trains in Japan. It includes conventional battery electric vehicles for the automotive application, conventional magnetic levitation trains with peak speeds of 300 km/h and superconductive levitation trains capable of speeds over 500 km/h in transcontinental service. These electric vehicles have been under development since 1971 and are now considered ready for introduction into intercity commercial service. Conventional magnetic levitation trains are targeted to connect New Chitose International Airport with Sapporo and shorter connections in LasVegas, Philadelphia and Miami. The first superconductive train is planned for the Osaka to Tokyo link by the year 2000, a distance of 515 km. The initial step has been taken with approval of funding for the first five year phase of construction beginning with the Kansai project near Osaka

  19. The JAK2 V617F mutation involves B- and T-lymphocyte lineages in a subgroup of patients with Philadelphia-chromosome negative chronic myeloproliferative disorders

    DEFF Research Database (Denmark)

    Larsen, Thomas Stauffer; Christensen, Jacob Haaber; Hasselbalch, Hans Carl

    2007-01-01

    The JAK2 V617F mutation is a frequent genetic event in the three classical Philadelphia-chromosome negative chronic myeloproliferative disorders (Ph(neg.)-CMPD), polycythemia vera (PV), essential thrombocythemia (ET) and idiopathic myelofibrosis (IMF). Its occurrence varies in frequency in regards...

  20. Muusikamaailm : Rostropovitsh Berliini müüri juures. Philadelphia Curtis Institute ئ 75. Lahti Linnaorkester Jaapanis ja USAs. Domingo taas Washingtonis / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    1999-01-01

    Berliini müüri langemise 10. aastapäevale pühendatud kontserdist 9. nov. Berliinis. Ameerika muusikakõrgkoolist Philadelphia Curtis Institute. Lahti Linnaorkestri kontserdireisist Jaapanisse ja USAsse. P. Domingo on sügishooajal esinenud erinevates Ameerika ooperiteatrites

  1. Muusikamaailm : Uus muusikasaal Philadelphias. Elgari teostekogu jätkatakse. Mortier tuleb ka Pariisi. Salonen loovutas Suomi-palkinto. Uusooper Dallases / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    2001-01-01

    Philadelphia sai uue kontserdisaali. Londoni kirjastus Novello jätkab Edward Elgari kogutud teoste väljaandmist. Belgia teatrimees ja ooperiadministraator Gerard Mortierist saab Ruhri kunstidetriennaali juht. Esa-Pekka Salonen loovutas oma 100 000margalise preemia kolmele noorele soome heliloojale. Dallase Ooperis tuli maailmaesiettekandele USA helilooja Tobias Pickeri ooper "Therese Raquin"

  2. STRIVE: Stress Resilience In Virtual Environments: a pre-deployment VR system for training emotional coping skills and assessing chronic and acute stress responses.

    Science.gov (United States)

    Rizzo, Albert; Buckwalter, J Galen; John, Bruce; Newman, Brad; Parsons, Thomas; Kenny, Patrick; Williams, Josh

    2012-01-01

    The incidence of posttraumatic stress disorder (PTSD) in returning OEF/OIF military personnel is creating a significant healthcare challenge. This has served to motivate research on how to better develop and disseminate evidence-based treatments for PTSD. One emerging form of treatment for combat-related PTSD that has shown promise involves the delivery of exposure therapy using immersive Virtual Reality (VR). Initial outcomes from open clinical trials have been positive and fully randomized controlled trials are currently in progress to further validate this approach. Based on our research group's initial positive outcomes using VR to emotionally engage and successfully treat persons undergoing exposure therapy for PTSD, we have begun development in a similar VR-based approach to deliver stress resilience training with military service members prior to their initial deployment. The Stress Resilience In Virtual Environments (STRIVE) project aims to create a set of combat simulations (derived from our existing Virtual Iraq/Afghanistan exposure therapy system) that are part of a multi-episode narrative experience. Users can be immersed within challenging combat contexts and interact with virtual characters within these episodes as part of an experiential learning approach for training a range of psychoeducational and cognitive-behavioral emotional coping strategies believed to enhance stress resilience. The STRIVE project aims to present this approach to service members prior to deployment as part of a program designed to better prepare military personnel for the types of emotional challenges that are inherent in the combat environment. During these virtual training experiences users are monitored physiologically as part of a larger investigation into the biomarkers of the stress response. One such construct, Allostatic Load, is being directly investigated via physiological and neuro-hormonal analysis from specimen collections taken immediately before and after

  3. Comparison of geographic methods to assess travel patterns of persons diagnosed with HIV in Philadelphia: how close is close enough?

    Science.gov (United States)

    Eberhart, Michael G; Share, Amanda M; Shpaner, Mark; Brady, Kathleen A

    2015-02-01

    Travel distance to medical care has been assessed using a variety of geographic methods. Network analyses are less common, but may generate more accurate estimates of travel costs. We compared straight-line distances and driving distance, as well as average drive time and travel time on a public transit network for 1789 persons diagnosed with HIV between 2010 and 2012 to identify differences overall, and by distinct geographic areas of Philadelphia. Paired t-tests were used to assess differences across methods, and analysis of variance was used to assess between-group differences. Driving distances were significantly longer than straight-line distances (ptravel costs, and may improve models to predict medical care outcomes. Copyright © 2014 Elsevier Inc. All rights reserved.

  4. Promoting good health in the age of reform: the medical publications of Henry H. Porter of Philadelphia, 1829-32.

    Science.gov (United States)

    Horrocks, T A

    1995-01-01

    In the early 1830s, the Philadelphia publisher Henry H. Porter rapidly published five journals, six books, and an almanac, works having a particular emphasis on health and personal hygiene. Porter's health publications linked the traditional message about the importance of personal hygiene to health to the messages conveyed by the flourishing American reform movements at the time, and his Journal of Health was among the first American medically oriented periodicals published for the layperson. Yet Porter did not survive in the intensely competitive and financially unstable book trade. This study examines Porter's health publications, attempting to explain why he chose to publish what he did, the message(s) his works contained, the audience(s) he tried to reach, and the failure of his business.

  5. Filadelfia y la botánica en Norteamérica Philadelphia and the Botany in North America

    Directory of Open Access Journals (Sweden)

    Alina Freire-Fierro

    2008-07-01

    Full Text Available El establecimiento y el desarrollo de la investigación botánica en Norteamérica se inician con la fundación de tres instituciones de Filadelfia, la American Philosophical Society en 1743, el Departamento de Botánica de la Universidad de Pennsylvania en 1768 y la Academia de Ciencias Naturales (PH en 1812. Algunos de los botánicos más influyentes durante los últimos cuatro siglos y en particular durante los siglos XVIII y XIX, vivieron en Filadelfia, entre ellos William Bartram (1699-1777, fundador del primer jardín botánico de Norteamérica, Benjamin Smith Barton (1766-1815, escritor del primer libro de texto de botánica en Estados Unidos y posiblemente en toda América, Federico Pursh (1774-1820, autor de una de las floras norteamericanas más completas del siglo XIX, Thomas Nuttall (1786-1859, autor de la primera flora norteamericana a nivel continental y Lewis David von Schweinitz (1780-1834, ampliamente reconocido como el padre de la micología norteamericana. Aunque la botánica alcanzó su cenit en Filadelfia durante el siglo XIX, continúa hoy contribuyendo al desarrollo de la botánica, gracias al aporte de muchas instituciones. El Herbario PH con sus más de 1,4 millones de especímenes y con la proporción más alta de tipos/totalidad de especímenes de todos los herbarios en los Estados Unidos, continúa siendo una fuente importante para estudios sistemáticos, no solo de taxones norteamericanos, sino también de otras regiones del mundo.The establishment and development of botanical research in North America began with the foundation of three Philadelphian institutions: The American Philosophical Society in 1743, the Botany Department at University of Pennsylvania in 1768 and the Academy of Natural Sciences of Philadelphia in 1812. Some of the most influential botanists of the last four centuries, and in particular, the 18th and 19th centuries lived in Philadelphia, including William Bartram (1699-1777, founder of the

  6. Characteristics of Black Men Who Have Sex With Men in Baltimore, Philadelphia, and Washington, D.C.: Geographic Diversity in Socio-Demographics and HIV Transmission Risk.

    Science.gov (United States)

    German, Danielle; Brady, Kathleen; Kuo, Irene; Opoku, Jenevieve; Flynn, Colin; Patrick, Rudy; Park, Ju Nyeong; Adams, Joella; Carroll, Makeda; Simmons, Ron; Smith, Carlton R; Davis, Wendy W

    2017-07-01

    Baltimore, Philadelphia, and Washington, DC are geographically proximate cities with high HIV prevalence, including among black men who have sex with men (BMSM). Using data collected among BMSM in CDC's National HIV Behavioral Surveillance project, we compared socio-demographic characteristics, HIV risk behaviors, and service utilization to explore similarities and differences that could inform local and regional HIV intervention approaches. BMSM were recruited through venue time location sampling, June-December, 2011. Participants completed identical socio-behavioral surveys and voluntary HIV testing. Analyses were conducted among the full sample and those aged 18-24. Participants included 159 (DC), 364 (Baltimore), and 331 (Philadelphia) eligible BMSM. HIV prevalence was 23.1% (DC), 48.0% (Baltimore), 14.6% (Philadelphia) with 30.6%, 69.0%, 33.3% unrecognized HIV infection, respectively. Among BMSM 18-24, HIV prevalence was 11.1% (DC), 38.9% (Baltimore), 9.6% (Philadelphia) with unrecognized HIV infection 0.0%, 73.8%, 60.0% respectively. Compared with the other 2 cities, Baltimore participants were less likely to identify as gay/homosexual; more likely to report unemployment, incarceration, homelessness, sex exchange; and least likely to use the internet for partners. DC participants were more likely to have a college degree and employment. Philadelphia participants were more likely to report gay/homosexual identity, receptive condomless anal sex, having only main partners, and bars/clubs as partner meeting places. Sexually transmitted disease testing was universally low. Analyses showed especially high HIV prevalence among BMSM in Baltimore including among young BMSM. Socio-demographic characteristics and HIV infection correlates differed across cities but unrecognized HIV infection and unknown partner status were universally high.

  7. Funding quality pre-kindergarten slots with Philadelphia's new 'sugary drink tax': simulating effects of using an excise tax to address a social determinant of health.

    Science.gov (United States)

    Langellier, Brent A; Lê-Scherban, Félice; Purtle, Jonathan

    2017-09-01

    Philadelphia passed a 1·5-cent-per-ounce sweetened beverage tax (SBT). Revenue will fund 10 000 quality pre-kindergarten slots for poor children. It is imperative to understand how revenue from SBT can be used to fund programmes to address education and other social determinants of health. The objective of the present study was to simulate quality pre-kindergarten attendance, educational achievement and sugar-sweetened beverage (SSB) consumption among Philadelphia children and adolescents under six intervention scenarios: (i) no intervention; (ii) 10 000 additional quality pre-kindergarten slots; (iii) a 1·5-cent-per-ounce SBT; (iv) expanded pre-kindergarten and 1·5-cent-per-ounce SBT; (v) a 3-cent-per-ounce SBT; and (vi) expanded pre-kindergarten and 3-cent-per-ounce SBT. We used an agent-based model to estimate pre-kindergarten enrolment, educational achievement and SSB consumption under the six policy scenarios. We identified key parameters in the model from the published literature and secondary analyses of the Panel Study of Income Dynamics - Child Development Supplement. Philadelphia, Pennsylvania, USA. Philadelphia children and adolescents aged 4-18 years. A 1·5-cents-per-ounce tax would reduce SSB consumption by 1·3 drinks/week among Philadelphia children and adolescents relative to no intervention, with larger effects among children below the poverty level. Quality pre-kindergarten expansion magnifies the effect of the SBT by 8 %, but has the largest effect on moderate-income children just above the poverty level. The SBT and quality pre-kindergarten programme each reduce SSB consumption, but primarily benefit different children and adolescents. Pairing an excise tax with a complementary programme to improve a social determinant of health represents a progressive strategy to combat obesity, a disease regressive in its social patterning.

  8. Electric emissions from electrical appliances

    International Nuclear Information System (INIS)

    Leitgeb, N.; Cech, R.; Schroettner, J.

    2008-01-01

    Electric emissions from electric appliances are frequently considered negligible, and standards consider electric appliances to comply without testing. By investigating 122 household devices of 63 different categories, it could be shown that emitted electric field levels do not justify general disregard. Electric reference values can be exceeded up to 11-fold. By numerical dosimetry with homogeneous human models, induced intra-corporal electric current densities were determined and factors calculated to elevate reference levels to accounting for reduced induction efficiency of inhomogeneous fields. These factors were found not high enough to allow generally concluding on compliance with basic restrictions without testing. Electric appliances usually simultaneously emit both electric and magnetic fields exposing almost the same body region. Since the sum of induced current densities is limited, one field component reduces the available margin for the other. Therefore, superposition of electric current densities induced by either field would merit consideration. (authors)

  9. Electricity Customers

    Science.gov (United States)

    Residential, commercial, and industrial customers each account for roughly one-third of the nation’s electricity use. The transportation sector also accounts for a small fraction of electricity, although it could increase.

  10. Electric drives

    CERN Document Server

    Boldea, Ion

    2005-01-01

    ENERGY CONVERSION IN ELECTRIC DRIVESElectric Drives: A DefinitionApplication Range of Electric DrivesEnergy Savings Pay Off RapidlyGlobal Energy Savings Through PEC DrivesMotor/Mechanical Load MatchMotion/Time Profile MatchLoad Dynamics and StabilityMultiquadrant OperationPerformance IndexesProblemsELECTRIC MOTORS FOR DRIVESElectric Drives: A Typical ConfigurationElectric Motors for DrivesDC Brush MotorsConventional AC MotorsPower Electronic Converter Dependent MotorsEnergy Conversion in Electric Motors/GeneratorsPOWER ELECTRONIC CONVERTERS (PECs) FOR DRIVESPower Electronic Switches (PESs)The

  11. Electrical contracting

    CERN Document Server

    Neidle, Michael

    2013-01-01

    Electrical Contracting, Second Edition is a nine-chapter text guide for the greater efficiency in planning and completing installations for the design, installation and control of electrical contracts. This book starts with a general overview of the efficient cabling and techniques that must be employed for safe wiring design, as well as the cost estimation of the complete electrical contract. The subsequent chapters are devoted to other electrical contracting requirements, including electronic motor control, lighting, and electricity tariffs. A chapter focuses on the IEE Wiring Regulations an

  12. Electric vehicles

    Science.gov (United States)

    1990-03-01

    Quiet, clean, and efficient, electric vehicles (EVs) may someday become a practical mode of transportation for the general public. Electric vehicles can provide many advantages for the nation's environment and energy supply because they run on electricity, which can be produced from many sources of energy such as coal, natural gas, uranium, and hydropower. These vehicles offer fuel versatility to the transportation sector, which depends almost solely on oil for its energy needs. Electric vehicles are any mode of transportation operated by a motor that receives electricity from a battery or fuel cell. EVs come in all shapes and sizes and may be used for different tasks. Some EVs are small and simple, such as golf carts and electric wheel chairs. Others are larger and more complex, such as automobile and vans. Some EVs, such as fork lifts, are used in industries. In this fact sheet, we will discuss mostly automobiles and vans. There are also variations on electric vehicles, such as hybrid vehicles and solar-powered vehicles. Hybrid vehicles use electricity as their primary source of energy, however, they also use a backup source of energy, such as gasoline, methanol or ethanol. Solar-powered vehicles are electric vehicles that use photovoltaic cells (cells that convert solar energy to electricity) rather than utility-supplied electricity to recharge the batteries. These concepts are discussed.

  13. The Effect of Selected Cleaning Techniques on Berkshire Lee Marble: A Scientific Study at Philadelphia City Hall

    Science.gov (United States)

    Mossotti, Victor G.; Eldeeb, A. Raouf; Fries, Terry L.; Coombs, Mary Jane; Naude, Virginia N.; Soderberg, Lisa; Wheeler, George S.

    2002-01-01

    This report describes a scientific investigation of the effects of eight different cleaning techniques on the Berkshire Lee marble component of the facade of the East Center Pavilion at Philadelphia City Hall; the study was commissioned by the city of Philadelphia. The eight cleaning techniques evaluated in this study were power wash (proprietary gel detergent followed by water rinse under pressure), misting (treatment with potable, nebulized water for 24-36 hours), gommage (proprietary Thomann-Hanry low-pressure, air-driven, small-particle, dry abrasion), combination (gommage followed by misting), Armax (sodium bicarbonate delivered under pressure in a water wash), JOS (dolomite powder delivered in a low-pressure, rotary-vortex water wash), laser (thermal ablation), and dry ice (powdered-dry-ice abrasion delivered under pressure). In our study approximately 160 cores were removed from the building for laboratory analysis. We developed a computer program to analyze scanning-electron-micrograph images for the microscale surface roughness and other morphologic parameters of the stone surface, including the near-surface fracture density of the stone. An analysis of more than 1,100 samples cut from the cores provided a statistical basis for crafting the essential elements of a reduced-form, mixed-kinetics conceptual model that represents the deterioration of calcareous stone in terms of self-organized soiling and erosion patterns. This model, in turn, provided a basis for identifying the variables that are affected by the cleaning techniques and for evaluating the extent to which such variables influence the stability of the stone. The model recognizes three classes of variables that may influence the soiling load on the stone, including such exogenous environmental variables as airborne moisture, pollutant concentrations, and local aerodynamics, and such endogenous stone variables as surface chemistry and microstructure (fracturing, roughness, and so on). This study

  14. Electric shock and electrical fire specialty

    International Nuclear Information System (INIS)

    2011-02-01

    This book deals with electric shock and electrical fire, which is made up seven chapters. It describes of special measurement for electric shock and electrical fire. It mentions concretely about electrical fire analysis and precautionary measurement, electrical shock analysis cases, occurrence of static electricity and measurement, gas accident, analysis of equipment accident and precautionary measurement. The book is published to educate the measurement on electric shock and electrical fire by electrical safety technology education center in Korea Electrical Safety Corporation.

  15. Goal motives and multiple-goal striving in sport and academia: A person-centered investigation of goal motives and inter-goal relations.

    Science.gov (United States)

    Healy, Laura C; Ntoumanis, Nikos; Duda, Joan L

    2016-12-01

    This investigation extended the goal striving literature by examining motives for two goals being pursued simultaneously. Grounded in self-determination theory, we examined how student-athletes' motives for their sporting and academic goals were associated with inter-goal facilitation and interference. Cross-sectional survey. UK university student-athletes (n=204) identified their most important sporting and academic goals. They then rated their extrinsic, introjected, identified and intrinsic motives for these goals and completed questionnaires assessing inter-goal facilitation and interference. Using a person-centered approach via latent profile analysis, we identified three distinct profiles of goal motives. Auxiliary analyses showed that the profile with high identified motives for both goals reported greater inter-goal facilitation. Extending the previous literature, the findings demonstrate the benefits of autonomous motives when simultaneously pursing goals in sport and academia. Copyright © 2016. Published by Elsevier Ltd.

  16. Acculturation and Post-Migration Stress in Middle-Aged Chinese Immigrant Women in Philadelphia: Variation between the Fujianese and the non-Fujianese women

    OpenAIRE

    Ying, Yu-Wen; Han, Meekyung; Tseng, Marilyn

    2012-01-01

    The experience of acculturation in Chinese immigrant women from the rural coastal province of Fujian has not been well studied despite of their growing numbers in American cities. This exploratory study is an attempt to examine the experience of acculturation and post-migration stress in Fujianese immigrant women as compared to those from other parts of China. The study is based on a convenience sample 240 Fujianese and 162 non-Fujianese Chinese immigrant women living in Philadelphia.

  17. Recurrent gastrointestinal hemorrhage in treatment with dasatinib in a patient showing SMAD4 mutation with acute lymphoblastic leukemia Philadelphia positive and juvenile polyposis hereditary hemorrhagic telangiectasia syndrome

    Directory of Open Access Journals (Sweden)

    Chiara Sartor

    2013-07-01

    Full Text Available We report a case of a patient affected by juvenile polyposis and hereditary hemorrhagic telangiectasia linked to a SMAD4 mutation who developed acute lymphoblastic leukemia positive for the Philadelphia chromosome translocation and with a complex karyotype. During the treatment with the tyrosine kinase inhibitor dasatinib the patient presented recurrent severe gastrointestinal hemorrhages linked to the genetic background and aggravated by thrombocytopenia.

  18. High Behavioral Approach System (BAS) sensitivity, reward responsiveness, and goal-striving predict first onset of bipolar spectrum disorders: a prospective behavioral high-risk design.

    Science.gov (United States)

    Alloy, Lauren B; Bender, Rachel E; Whitehouse, Wayne G; Wagner, Clara A; Liu, Richard T; Grant, David A; Jager-Hyman, Shari; Molz, Ashleigh; Choi, James Y; Harmon-Jones, Eddie; Abramson, Lyn Y

    2012-05-01

    A prospective, behavioral high-risk design provided a theoretically guided examination of vulnerability to first onset of bipolar spectrum disorder based on the Behavioral Approach System (BAS) model. Adolescents (ages 14-19) at an "age of risk" for bipolar disorder onset were screened on BAS sensitivity by interviewers blind to current symptoms, lifetime history, and family history of psychopathology. Participants were selected with high versus moderate levels of BAS sensitivity and administered a lifetime diagnostic interview. Those with a bipolar spectrum disorder, psychosis, or hypomanic episode with onset prior to the BAS sensitivity assessment were excluded. High BAS (n = 171) and moderate BAS (n = 119) sensitivity participants in the final sample completed baseline measures of symptoms, goal-setting, and reward responsiveness and were followed prospectively with semistructured diagnostic interviews every 6 months. Consistent with the vulnerability hypothesis of the BAS model of bipolar disorder, high BAS participants had a greater likelihood, and shorter time to onset, of bipolar spectrum disorder than moderate BAS participants across an average of 12.8 months of follow-up (12.9% vs. 4.2%), controlling for baseline depressive and hypomanic symptoms, and family history of bipolar disorder. High reward responsiveness on a behavioral task and ambitious goal-striving for popular fame and financial success (but not impulsivity) also predicted first onset of bipolar spectrum disorder controlling for the covariates and BAS risk group, and ambitious goal-striving partially mediated the BAS risk group effect. We discuss implications of the findings for the BAS model of bipolar disorder and early intervention efforts.

  19. Innovative STRoke Interactive Virtual thErapy (STRIVE) online platform for community-dwelling stroke survivors: a randomised controlled trial protocol.

    Science.gov (United States)

    Johnson, Liam; Bird, Marie-Louise; Muthalib, Makii; Teo, Wei-Peng

    2018-01-09

    The STRoke Interactive Virtual thErapy (STRIVE) intervention provides community-dwelling stroke survivors access to individualised, remotely supervised progressive exercise training via an online platform. This trial aims to determine the clinical efficacy of the STRIVE intervention and its effect on brain activity in community-dwelling stroke survivors. In a multisite, assessor-blinded randomised controlled trial, 60 stroke survivors >3 months poststroke with mild-to-moderate upper extremity impairment will be recruited and equally randomised by location (Melbourne, Victoria or Launceston, Tasmania) to receive 8 weeks of virtual therapy (VT) at a local exercise training facility or usual care. Participants allocated to VT will perform 3-5 upper limb exercises individualised to their impairment severity and preference, while participants allocated to usual care will be asked to maintain their usual daily activities. The primary outcome measures will be upper limb motor function and impairment, which will be assessed using the Action Research Arm Test and Upper Extremity Fugl-Meyer, respectively. Secondary outcome measures include upper extremity function and spasticity, as measured by the box and block test and Modified AshworthScale, respectively, and task-related changes in bilateral sensorimotor cortex haemodynamics during hand reaching and wrist extension movements as measured by functional near-infrared spectroscopy. Quality of life will be measured using the Euro-Quality of Life-5 Dimension-5 Level Scale, and the Motor Activity Log-28 will be used to measure use of the hemiparetic arm. All measures will be assessed at baseline and immediately postintervention. The study was approved by the Deakin University Human Research Ethics Committee in May 2017 (No. 2017-087). The results will be disseminated in peer-reviewed journals and presented at major international stroke meetings. ACTRN12617000745347; Pre-results. © Article author(s) (or their employer(s) unless

  20. Electricity saving in households-A social cognitive approach

    International Nuclear Information System (INIS)

    Thogersen, John; Gronhoj, Alice

    2010-01-01

    We propose a conceptual framework for understanding the (lack of) energy saving efforts of private households based on Bandura's (1986) social cognitive theory. Results from applying this framework on a sample of Danish private electricity consumers are presented and it is concluded (a) that households' electricity consumption depends on both structural and motivational factors, (b) that their electricity saving effort depends on the strength of their internalized norms or self-expectations and on self-efficacy related factors, and (c) that there are predictable patterns of interaction among household members that influence their electricity consumption. The results suggest two approaches to promote electricity saving in households: (1) to change the socio-structural environment to be more facilitating for energy saving and empower householders to be more effective in their striving towards this goal through improved feedback about their household's electricity consumption and (2) social norms marketing, communicating social expectations and others' successful electricity saving achievements. - Research highlights: →A combination of survey and meter reading data is used to analyze energy saving in households. →Up to two adults from each household answered the questionnaire. →Dyadic data analysis is used to investigate interactions between household members. →Both structural and motivational factors account for households' electricity consumption. →Electricity saving efforts depends on internalized norms, self-efficacy and social interaction.

  1. Electricity saving in households-A social cognitive approach

    Energy Technology Data Exchange (ETDEWEB)

    Thogersen, John, E-mail: jbt@asb.d [Aarhus University, School of Business and Social Sciences, Department of Marketing, Haslegaardsvej 10, DK-8210 Aarhus (Denmark); Gronhoj, Alice, E-mail: alg@asb.d [Aarhus University, School of Business and Social Sciences, Department of Marketing, Haslegaardsvej 10, DK-8210 Aarhus (Denmark)

    2010-12-15

    We propose a conceptual framework for understanding the (lack of) energy saving efforts of private households based on Bandura's (1986) social cognitive theory. Results from applying this framework on a sample of Danish private electricity consumers are presented and it is concluded (a) that households' electricity consumption depends on both structural and motivational factors, (b) that their electricity saving effort depends on the strength of their internalized norms or self-expectations and on self-efficacy related factors, and (c) that there are predictable patterns of interaction among household members that influence their electricity consumption. The results suggest two approaches to promote electricity saving in households: (1) to change the socio-structural environment to be more facilitating for energy saving and empower householders to be more effective in their striving towards this goal through improved feedback about their household's electricity consumption and (2) social norms marketing, communicating social expectations and others' successful electricity saving achievements. - Research highlights: {yields}A combination of survey and meter reading data is used to analyze energy saving in households. {yields}Up to two adults from each household answered the questionnaire. {yields}Dyadic data analysis is used to investigate interactions between household members. {yields}Both structural and motivational factors account for households' electricity consumption. {yields}Electricity saving efforts depends on internalized norms, self-efficacy and social interaction.

  2. Electric Substations

    Data.gov (United States)

    Department of Homeland Security — Substations. Substations are facilities and equipment that switch, transform, or regulate electric voltage. The Substations feature class includes taps, a location...

  3. Atmospheric electricity

    CERN Document Server

    Chalmers, J Alan

    1957-01-01

    Atmospheric Electricity brings together numerous studies on various aspects of atmospheric electricity. This book is composed of 13 chapters that cover the main problems in the field, including the maintenance of the negative charge on the earth and the origin of the charges in thunderstorms. After a brief overview of the historical developments of atmospheric electricity, this book goes on dealing with the general principles, results, methods, and the MKS system of the field. The succeeding chapters are devoted to some aspects of electricity in the atmosphere, such as the occurrence and d

  4. Developing a Community-Wide Initiative to Address Childhood Adversity and Toxic Stress: A Case Study of The Philadelphia ACE Task Force.

    Science.gov (United States)

    Pachter, Lee M; Lieberman, Leslie; Bloom, Sandra L; Fein, Joel A

    The Philadelphia ACE Task Force is a community based collaborative of health care providers, researchers, community-based organizations, funders, and public sector representatives. The mission of the task force is to provide a venue to address childhood adversity and its consequences in the Philadelphia metropolitan region. In this article we describe the origins and metamorphosis of the Philadelphia ACE Task Force, which initially was narrowly focused on screening for adverse childhood experiences (ACEs) in health care settings but expanded its focus to better represent a true community-based approach to sharing experiences with addressing childhood adversity in multiple sectors of the city and region. The task force has been successful in developing a research agenda and conducting research on ACEs in the urban context, and has identified foci of local activity in the areas of professional training and workforce development, community education, and local practical interventions around adversity, trauma, and resiliency. In this article we also address the lessons learned over the first 5 years of the task force's existence and offers recommendations for future efforts to build a local community-based ACEs collaborative. Copyright © 2017 Academic Pediatric Association. Published by Elsevier Inc. All rights reserved.

  5. Age but not Philadelphia positivity impairs outcome in older/elderly patients with acute lymphoblastic leukemia in Sweden.

    Science.gov (United States)

    Kozlowski, Piotr; Lennmyr, Emma; Ahlberg, Lucia; Bernell, Per; Hulegårdh, Erik; Karbach, Holger; Karlsson, Karin; Tomaszewska-Toporska, Beata; Åström, Maria; Hallböök, Heléne

    2017-08-01

    Older/elderly patients with acute lymphoblastic leukemia (ALL) are poorly represented in clinical trials. Using Swedish national leukemia registries, we investigated disease/patient characteristics, treatment choices, outcome, and the impact of an age-adapted protocol (introduced in 2009) in this population-based study of patients aged 55-85 years, diagnosed with ALL 2005-2012. Of 174 patients, 82% had B-phenotype, 11% Burkitt leukemia (excluded), and 7% T-phenotype. Philadelphia chromosome positivity (Ph+) occurred in 35%. Of the 155 B- and T-ALL patients, 80% were treated with intensive protocols, and 20% with a palliative approach. Higher age and WHO performance status ≥2 influenced the choice of palliation. Intensive, palliative, and both approaches resulted in complete remission rate 83/16/70% and 3-year overall survival (OS) 32/3/26%. The age-adapted protocol did not improve outcome. With intensive treatment, platelet count ≤35×10 9 /L and age ≥75 years were adverse prognostic factors for OS, Ph+ was not. Male sex was an adverse prognostic factor in the 55-64 year age-group. We report a high frequency of Ph+ in older/elderly patients, with no evidence of poorer outcome compared to Ph-negative disease. Overall prognosis for elderly patients with ALL remains dismal, despite the use of age-adapted treatment. © 2017 The Authors. European Journal of Haematology Published by John Wiley & Sons Ltd.

  6. An Unsuspected Finding of t(9;22: A Rare Case of Philadelphia Chromosome-Positive B-Lymphoblastic Lymphoma

    Directory of Open Access Journals (Sweden)

    Prajwal Boddu

    2017-01-01

    Full Text Available While rare, cases of isolated extramedullary disease of B-cell Lymphoblastic Lymphoma (B-LBL without morphologic bone marrow involvement have been described. In this report, we illustrate the case of an elderly gentleman who presented with isolated testicular and vertebral LBL involvement but had no morphologic bone marrow involvement. The initial plan of treatment was to treat along the lines of Philadelphia negative B-ALL/LBL. During this time, fluorescence in situ hybridization (FISH and PCR testing for BCR-ABL1 rearrangements were being performed on the marrow specimens as a part of routine diagnostic workup. While the FISH returned negative, PCR testing unexpectedly detected BCR-ABL1 fusion transcripts at a low level of 0.48%. Given their presence, we performed FISH for BCR/ABL1 rearrangement in both testicular and L5 vertebral specimens which were 80–90% positive. He subsequently received rituximab, hyper-CVAD, and dasatinib, along with prophylactic intrathecal prophylactic chemotherapy. The patient achieved a prolonged remission but eventually relapsed, 4 years later. Had it not been for this fortuitous discovery, the patient would not have been treated with tyrosine kinase inhibitors. We emphasize that FISH and PCR testing for BCR-ABL1 rearrangement are integral to arriving at an accurate diagnosis and should be routinely tested on B-LBL biopsy specimens.

  7. The insight and challenge of reflexive practice in an ethnographic study of black traumatically injured patients in Philadelphia.

    Science.gov (United States)

    Jacoby, Sara F

    2017-07-01

    The integrity of critical ethnography requires engagement in reflexive practice at all phases of the research process. In this discussion paper, I explore the insights and challenges of reflexive practice in an ethnographic study of the recovery experiences of black trauma patients in a Philadelphia hospital. Observation and interviews were conducted with twelve patients who were admitted to trauma-designated units of the hospital over the course of a year. During fieldwork, I learned the ways that my background as a professional nurse structured my way of being in clinical space and facilitated a particular interpretation of clinical culture. In analysis, reflection on subjectivities through which I designed this ethnographic research allowed me to see beyond my preconceived and theoretically informed perspective to permit unexpected features of the field to emerge. Reflexive practice also guided my reconciliation of key practical and epistemological differences between clinical ethnographic research and the anthropologic tradition in which it is rooted. I conclude that with careful reflection to the subjectivities that influence the research process, interdisciplinary clinically relevant applied interpretations of critical ethnographic work can be used to generate detailed knowledge across contexts in clinical care, nursing practice, and patient experiences. © 2016 John Wiley & Sons Ltd.

  8. Frequency of JAK2 V617F mutation in patients with Philadelphia positive Chronic Myeloid Leukemia in Pakistan.

    Science.gov (United States)

    Tabassum, Najia; Saboor, Mohammed; Ghani, Rubina; Moinuddin, Moinuddin

    2014-01-01

    Co-existence of myeloproliferative disorders (MPD) and Janus associated kinase 2 mutation (JAK2 V617F) is a well-established fact. Only few case reports are available showing presence of JAK2 V617F mutation in chronic myeloid leukemia (CML). Purpose of this study was to determine the frequency of JAK2 V617F mutation in Philadelphia Chromosome positive (Ph (+)) CML patients in Pakistan. The study was conducted from August 2009 to July 2010 at Civil Hospital and Baqai Institute of Hematology (BIH) Karachi. Blood samples from 25 patients with CML were collected. Multiplex reverse transcription polymerase chain reaction (RT-PCR) was performed for Breakpoint Cluster Region - Abelson (BCR-ABL) rearrangement. Conventional PCR was performed for JAK2 V617F mutation on BCR-ABL positive samples. All 25 samples showed BCR-ABL rearrangement. Out of these 11 samples (44%) had JAK2 V617F mutation; the remaining 14 (56%) cases showed JAK2 617V wild type. It is concluded that the co-existence of Ph (+)CML and JAK2 V617F mutation is possible.

  9. Chromosome abnormalities additional to the Philadelphia chromosome at the diagnosis of chronic myelogenous leukemia: pathogenetic and prognostic implications.

    Science.gov (United States)

    Zaccaria, Alfonso; Testoni, Nicoletta; Valenti, Anna Maria; Luatti, Simona; Tonelli, Michela; Marzocchi, Giulia; Cipriani, Raffaella; Baldazzi, Carmen; Giannini, Barbara; Stacchini, Monica; Gamberini, Carla; Castagnetti, Fausto; Rosti, Gianantonio; Azzena, Annalisa; Cavazzini, Francesco; Cianciulli, Anna Maria; Dalsass, Alessia; Donti, Emilio; Giugliano, Emilia; Gozzetti, Alessandro; Grimoldi, Maria Grazia; Ronconi, Sonia; Santoro, Alessandra; Spedicato, Francesco; Zanatta, Lucia; Baccarani, Michele

    2010-06-01

    Additional chromosome abnormalities (ACAs) occur in less than 10% of cases at diagnosis of Philadelphia chromosome (Ph)-positive chronic myelogenous leukemia (CML). In some cases, on the basis of the persistence of the ACAs in Ph-negative cells after response to imatinib, a secondary origin of the Ph chromosome has been demonstrated. In this study, the possible prognostic value of this phenomenon was evaluated. Thirty-six Ph-positive CML patients were included in the study. In six patients, ACAs persisted after the disappearance of the Ph. A complete cytogenetic response (CCR) was obtained in five of these six patients, and five of six also had a high Sokal score. In all the other cases, ACAs disappeared together (in cases of response to therapy with imatinib) or persisted with the Ph (in cases of no response to imatinib). In the former cases, the primary origin of the Ph was demonstrated. CCR was obtained in 22 cases (17 with low to intermediate Sokal scores), while no response was observed in 8 patients (5 with a high Sokal score). Sokal score seems to maintain its prognostic value for patients in whom the Ph occurs as a primary event, but not in those in whom it occurs as a secondary one. Copyright 2010 Elsevier Inc. All rights reserved.

  10. Inspection Frequency, Sociodemographic Factors, and Food Safety Violations in Chain and Nonchain Restaurants, Philadelphia, Pennsylvania, 2013-2014.

    Science.gov (United States)

    Leinwand, Sarah E; Glanz, Karen; Keenan, Brendan T; Branas, Charles C

    We explored how restaurant inspection frequency and restaurant neighborhood sociodemographic characteristics are related to food safety inspection outcomes in chain and nonchain restaurants to better understand external factors that may influence inspection outcomes. We categorized the results of restaurant inspections in Philadelphia, Pennsylvania, in 2013 and 2014 by restaurant type (chain or nonchain), inspection frequency (1, 2, or ≥3 per 2-year study period), and violation type (total number of violations, foodborne-illness risk factor violation, or good retail practice violation). We collected 2013 US Census block group sociodemographic data for each restaurant neighborhood. We used nested mixed-effects regression analyses to determine the association between restaurant inspection frequency and inspection violations, as well as between inspection violations and restaurant neighborhood sociodemographic variables, stratified by restaurant type. Compared with nonchain restaurants, chain restaurants had significantly fewer total violations per inspection (mean [SD]: 6.5 [4.6] vs 9.6 [6.8] violations, P chain restaurants. For nonchain restaurants, a higher proportion of black residents in a restaurant neighborhood was associated with 0.6 ( P food safety inspection frequency, based on whether or not restaurants are part of chains, could reduce the frequency of violations, particularly in restaurants with the most violations.

  11. Factors Influencing the Behavioural Intention towards Full Electric Vehicles: An Empirical Study in Macau

    Directory of Open Access Journals (Sweden)

    Ivan K. W. Lai

    2015-09-01

    Full Text Available This study examines the factors that influence individual intentions towards the adoption of full electric vehicles. A sample including 308 respondents was collected on the streets of Macau. The collected data were analysed by confirmatory factor analysis and structural equation modelling. The results demonstrate that environmental concerns and the perception of environmental policy are antecedent factors of the perception of full electric vehicles, which influences the behavioural intention to purchase full electric vehicles. This study also finds that the perception of economic benefit is one of the key factors influencing the adoption of full electric vehicles. Vehicle operators seek economic benefits from future long-term fuel savings, high energy efficiency, and cheap electricity. Thus, a government striving to promote low-carbon transportation needs to scale up its efforts to enhance citizens’ environmental concerns and to establish proper environmental policy as well as to provide long-term financial and strategic support for electric vehicles.

  12. Electric machine

    Science.gov (United States)

    El-Refaie, Ayman Mohamed Fawzi [Niskayuna, NY; Reddy, Patel Bhageerath [Madison, WI

    2012-07-17

    An interior permanent magnet electric machine is disclosed. The interior permanent magnet electric machine comprises a rotor comprising a plurality of radially placed magnets each having a proximal end and a distal end, wherein each magnet comprises a plurality of magnetic segments and at least one magnetic segment towards the distal end comprises a high resistivity magnetic material.

  13. Teaching Electricity.

    Science.gov (United States)

    Iona, Mario

    1982-01-01

    To clarify the meaning of electrical terms, a chart is used to compare electrical concepts and relationships with a more easily visualized system in which water flows from a hilltop reservoir through a pipe to drive a mill at the bottom of the hill. A diagram accompanies the chart. (Author/SK)

  14. Sustainability in Electricity Markets. Study for the Dutch Transition Platform on Sustainable Electricity

    International Nuclear Information System (INIS)

    2005-12-01

    The current energy system is not sustainable. This situation is liable to lead to serious and costly consequences in the long term. The two most important themes to be addressed are climate change and securing energy supplies, particularly in view of the increasing dependency on fossil fuels from geo-politically unstable regions. That is why the Dutch government has decided to strive for a transition towards a Sustainable Energy System. The aim of the energy transition is to transform the current energy system over the coming decades into a sustainable energy system. The participants in this Energy Transition have established six themes for achieving a sustainable energy economy within 50 years. Within these themes experiments are being conducted, experiments that ensure that the final aims become clearer and feasible. Market participants, scientific and civil organizations, and government agencies are taking the lead in each of the six themes: (a) Green raw materials; (b) Sustainable Mobility; (c) Chain Efficiency; (d) New Gas; (e) Sustainable Electricity; (f) Energy in the built environment. This document provides input for the theme on Sustainable Electricity. The Dutch Ministry of Economic Affairs together with SenterNovem is preparing a Platform Renewable Electricity Supply. In this Platform representatives from different stakeholders are to take part. The platform is meant to stimulate concrete actions/initiatives towards sustainable electricity supply. SenterNovem has asked PricewaterhouseCoopers (PwC) to make an international inventory of electricity market developments, with a focus on the impact for future sustainable electricity supply. The question which options for electricity generation are the most suitable for a sustainable electricity supply will be dealt with by KEMA (a Dutch research institute for the electric power industry)

  15. Electric drives

    Energy Technology Data Exchange (ETDEWEB)

    1986-10-01

    Several electric vehicles have been tested in long-term tests, i.e. an electric passenger car (maximum speed 115 km/h) and several busses for use in pedestrians' zones, spas, airports, natural reserves, and urban transportation (DUO busses). The ICE high-speed train is discussed in some detail, i.e. its aeroacoustic and aerodynamic design, running gear, computer-controlled drives and brakes, diagnostic systems, and electrical equipment. The Berlin Maglev system is mentioned as well as current inverters in rail vehicles. (HWJ).

  16. Philadelphia chromosome-positive adult acute leukemia with monosomy of chromosome number seven: a subgroup with poor response to therapy.

    Science.gov (United States)

    Maddox, A M; Keating, M J; Trujillo, J; Cork, A; Youness, E; Ahearn, M J; McCredie, K B; Freireich, E J

    1983-01-01

    Thirty-four adult patients were seen at the University of Texas M. D. Anderson Hospital and Tumor Institute at Houston, Texas between 1969 and 1980 with acute leukemia (AL) and a deleted G-group chromosome that was shown by Giemsa banding to be a Philadelphia (Ph1) chromosome t(9;22) in 21 patients. Fourteen had the Ph1 chromosome as the sole abnormality, 12 had the Ph1 chromosome and loss of one chromosome of the C-group (identified by Giemsa banding analysis as number 7 in eight patients), while eight had the Ph1 chromosome and other changes. These three groups were similar in sex, age distribution and hematologic parameters. The median age of 40 was lower than usually seen in AL. The distribution of the morphologic subtypes was similar to that seen at this institution, with 50% being acute myeloblastic, 12% acute myelomonocytic, 20% lymphoblastic and 18% acute undifferentiated. The complete remission rate with chemotherapy was low: 25% in the Ph1 +/- 7, 50% in the Ph1 +/other group and 43% in the Ph1 +/other group. Median survival time was 8 months for the Ph1 +/- 7 group, 5.5 months for the Ph1 +/other group and 9.0 months for the Ph1 +/alone group. These patients with Ph1 + AL had higher white blood cell counts, increased extramedullary disease and poorer responses to therapy than usual for patients with AL. The deletion of chromosome 7 and the acquisition of the Ph1 chromosome identifies a group of patients with characteristics similar to all the patients with Ph1 + AL but a poor response to therapy and short remission duration.

  17. Knowledge, perceptions, and behaviors related to salt use among Philadelphia Chinese take-out restaurant owners and chefs.

    Science.gov (United States)

    Ma, Grace X; Shive, Steve; Zhang, Yolanda; Aquilante, Jennifer; Tan, Yin; Zhao, Mei; Solomon, Sara; Zhu, Steven; Toubbeh, Jamil; Colby, Lisa; Mallya, Giridhar; Zeng, Qiaoling

    2014-09-01

    Most of the sodium Americans consume comes from processed and restaurant foods. An upstream global strategy to promote health is to work with local restaurants to reduce sodium content in their food offerings, while accounting for food taste and economic considerations. In urban communities, Chinese take-out restaurants serve meals with large amounts of sodium and are clustered in low-income, racial/ethnic minority communities with a high prevalence of hypertension. The objective of this study is to assess baseline knowledge, attitudes, and behaviors related to sodium use/consumption among Chinese take-out owners and chefs recruited to participate in the Philadelphia Healthy Chinese Take-Out Initiative. A cross-sectional study of 221 Chinese take-out restaurants was conducted from August 2012 to February 2013. Items measured knowledge, attitudes, and behaviors related to salt use, salt consumption, and health. Most owners/chefs knew that excess sodium consumption contributes to high blood pressure but were less aware of other health effects and of major sources of sodium in the U.S. diet. The majority were willing and able to reduce sodium content in meals if customer demand could be maintained, and they desired training in food preparation, procurement, and marketing. Findings show a need to provide education, strategies, and support to Chinese take-out owners/chefs in preparing low-salt dishes. The results of this and future studies to reduce sodium content in meals by working with restaurant owners and chefs have global health promotion implications. © 2014 Society for Public Health Education.

  18. Sales of healthy snacks and beverages following the implementation of healthy vending standards in City of Philadelphia vending machines.

    Science.gov (United States)

    Pharis, Meagan L; Colby, Lisa; Wagner, Amanda; Mallya, Giridhar

    2018-02-01

    We examined outcomes following the implementation of employer-wide vending standards, designed to increase healthy snack and beverage options, on the proportion of healthy v. less healthy sales, sales volume and revenue for snack and beverage vending machines. A single-arm evaluation of a policy utilizing monthly sales volume and revenue data provided by the contracted vendor during baseline, machine conversion and post-conversion time periods. Study time periods are full calendar years unless otherwise noted. Property owned or leased by the City of Philadelphia, USA. Approximately 250 vending machines over a 4-year period (2010-2013). At post-conversion, the proportion of sales attributable to healthy items was 40 % for snacks and 46 % for beverages. Healthy snack sales were 323 % higher (38·4 to 162·5 items sold per machine per month) and total snack sales were 17 % lower (486·8 to 402·1 items sold per machine per month). Healthy beverage sales were 33 % higher (68·2 to 90·6 items sold per machine per month) and there was no significant change in total beverage sales (213·2 to 209·6 items sold per machine per month). Revenue was 11 % lower for snacks ($US 468·30 to $US 415·70 per machine per month) and 21 % lower for beverages ($US 344·00 to $US 270·70 per machine per month). Sales of healthy vending items were significantly higher following the implementation of employer-wide vending standards for snack and beverage vending machines. Entities receiving revenue-based commission payments from vending machines should employ strategies to minimize potential revenue losses.

  19. Methylation profiling of SOCS1, SOCS2, SOCS3, CISH and SHP1 in Philadelphia-negative myeloproliferative neoplasm.

    Science.gov (United States)

    Zhang, Min Yue; Fung, Tsz Kin; Chen, Fang Yuan; Chim, Chor Sang

    2013-10-01

    Janus kinase-signal transducer and activator of transcription (JAK/STAT) signalling, pivotal in Philadelphia-negative (Ph-ve) myeloproliferative neoplasm (MPN), is negatively regulated by molecules including SOCSs, CISH and SHP1. SOCS1, SOCS2 and SOCS3 methylation have been studied in MPN with discordant results. Herein, we studied the methylation status of SOCS1, SOCS2 and SOCS3, CISH and SHP1 by methylation-specific polymerase chain reaction (MSP) in cell lines and 45 diagnostic marrow samples of Ph-ve MPN. Moreover, we attempted to explain the discordance of methylation frequency by mapping the studied MSP primers to the respective genes. Methylation was detected in normal controls using SOCS2 MSP primers in the 3'translated exonic sequence, but not primers around the transcription start site in the 5' untranslated regions (5'UTR). SOCS1, SOCS2, SOCS3 and CISH were completely unmethylated in primary MPN samples and cell lines. In contrast, methylation of SHP1 was detected in 8.9% primary marrow samples. Moreover, SHP1 was completely methylated in K562 cell line, leading to reversible SHP1 silencing. A review of methylation studies of SOCS1 and SOCS3 showed that spuriously high rates of SOCS methylation had been reported using MSP primers targeting CpG sites in the 3'translated exonic sequence, which is also methylated in normal controls. However, using MSP primers localized to the 5'UTR, methylation of SOCS1, SOCS2 and SOCS3 is infrequent across all studies. In summary, methylation of SOCS1, SOCS2, SOCS3 and CISH is infrequent in Ph-ve MPN. Appropriate MSP primers are important for accurate estimation of the methylation frequency. The role of SHP1 methylation in the pathogenesis of MPN warrants further investigation. © 2013 The Authors. Journal of Cellular and Molecular Medicine published by John Wiley & Sons Ltd and Foundation for Cellular and Molecular Medicine.

  20. Storing empty calories and chronic disease risk: snack-food products, nutritive content, and manufacturers in Philadelphia corner stores.

    Science.gov (United States)

    Lucan, Sean C; Karpyn, Allison; Sherman, Sandy

    2010-05-01

    Corner stores are part of the urban food environment that may contribute to obesity and diet-related diseases, particularly for low-income and minority children. The snack foods available in corner stores may be a particularly important aspect of an urban child's food environment. Unfortunately, there is little data on exactly what snack foods corner stores stock, or where these foods come from. We evaluated snack foods in 17 Philadelphia corner stores, located in three ethnically distinct, low-income school neighborhoods. We recorded the manufacturer, calories, fat, sugar, and sodium for all snack items, excluding candy and prepared foods. We then compared the nutritive content of assessed snack items to established dietary recommendations and a school nutrition standard. In total, stores stocked 452 kinds of snacks, with only 15% of items common between all three neighborhoods. Total and unique snacks and snack food manufacturers varied by neighborhood, but distributions in snack type varied negligibly: overall, there were no fruit snacks, no vegetable snacks, and only 3.6% of all snacks (by liberal definition) were whole grain. The remainder (96.4% of snacks) was highly processed foods. Five of 65 manufacturers supplied 73.4% of all kinds of snack foods. Depending on serving size definition, 80.0-91.5% of snack foods were "unhealthy" (by the school nutrition standard), including seven of 11 wholegrain products. A single snack item could supply 6-14% of a day's recommended calories, fat, sugar, and sodium on average (or 56-169% at the extreme) for a "typical" child. We conclude that corner store snack food inventories are almost entirely unhealthful, and we discuss possible implications and next steps for research and intervention.

  1. Improving fruit and vegetable consumption among low-income customers at farmers markets: Philly Food Bucks, Philadelphia, Pennsylvania, 2011.

    Science.gov (United States)

    Young, Candace R; Aquilante, Jennifer L; Solomon, Sara; Colby, Lisa; Kawinzi, Mukethe A; Uy, Nicky; Mallya, Giridhar

    2013-10-03

    We evaluated whether Philly Food Bucks, a bonus incentive program at farmers markets, is associated with increased fruit and vegetable consumption and Supplemental Nutrition Assistance Program (SNAP) sales at farmers markets in low-income areas. A convenience sample of 662 customers at 22 farmers markets in low-income neighborhoods in Philadelphia, Pennsylvania, was surveyed via face-to-face interviews. Questions addressed shopping characteristics, self-reported change in fruit and vegetable consumption, whether customers tried new fruits or vegetables, use of Philly Food Bucks, and demographic information. Market-level SNAP sales and Philly Food Bucks redemption data were also collected to monitor sales patterns. Philly Food Bucks users were significantly more likely than nonusers to report increasing fruit and vegetable consumption (OR, 2.4; 95% CI, 1.6-3.7; P < .001) and to report trying new fruits or vegetables (OR 1.8; 95% CI, 1.2-2.7; P = .006). At the market level, average SNAP sales more than doubled at farmers markets in low-income areas in the first 2 years of the Philly Food Bucks program. At the city's largest farmers market in a low-income area, the program was associated with an almost 5-fold higher increase in annual SNAP sales compared with baseline. Results from this study demonstrate that a bonus incentive program tied to SNAP was associated with self-reported increases in fruit and vegetable consumption and increased SNAP sales at participating farmers markets in low-income communities. More research is warranted to evaluate the long-term impact of bonus incentives on farmers market use, dietary behaviors, and health outcomes.

  2. Characterization and Prognosis Significance of JAK2 (V617F), MPL, and CALR Mutations in Philadelphia-Negative Myeloproliferative Neoplasms

    Science.gov (United States)

    Singdong, Roongrudee; Siriboonpiputtana, Teerapong; Chareonsirisuthigul, Takol; Kongruang, Adcharee; Limsuwanachot, Nittaya; Sirirat, Tanasan; Chuncharunee, Suporn; Rerkamnuaychoke, Budsaba

    2016-10-01

    Background: The discovery of somatic acquired mutations of JAK2 (V617F) in Philadelphia-negative myeloproliferative neoplasms (Ph-negative MPNs) including polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF) has not only improved rational disease classification and prognostication but also brings new understanding insight into the pathogenesis of diseases. Dosage effects of the JAK2 (V617F) allelic burden in Ph-negative MPNs may partially influence clinical presentation, disease progression, and treatment outcome. Material and Methods: Pyrosequencing was performed to detect JAK2 (V617F) and MPL (W515K/L) and capillary electrophoresis to identify CALR exon 9.0 mutations in 100.0 samples of Ph-negative MPNs (38.0 PV, 55 ET, 4 PMF, and 3 MPN-U). Results: The results showed somatic mutations of JAK2 (V617F) in 94.7% of PV, 74.5% of ET, 25.0% of PMF, and all MPN-U. A high proportion of JAK2 (V617F) mutant allele burden (mutational load > 50.0%) was predominantly observed in PV when compared with ET. Although a high level of JAK2 (V617F) allele burden was strongly associated with high WBC counts in both PV and ET, several hematological parameters (hemoglobin, hematocrit, and platelet count) were independent of JAK2 (V617F) mutational load. MPL (W515K/L) mutations could not be detected whereas CALR exon 9.0 mutations were identified in 35.7% of patients with JAK2 negative ET and 33.3% with JAK2 negative PMF. Conclusions: The JAK2 (V617F) allele burden may be involved in progression of MPNs. Furthermore, a high level of JAK2 (V617F) mutant allele appears strongly associated with leukocytosis in both PV and ET. Creative Commons Attribution License

  3. Costs of a community-based glaucoma detection programme: analysis of the Philadelphia Glaucoma Detection and Treatment Project.

    Science.gov (United States)

    Pizzi, Laura T; Waisbourd, Michael; Hark, Lisa; Sembhi, Harjeet; Lee, Paul; Crews, John E; Saaddine, Jinan B; Steele, Deon; Katz, L Jay

    2018-02-01

    Glaucoma is the foremost cause of irreversible blindness, and more than 50% of cases remain undiagnosed. Our objective was to report the costs of a glaucoma detection programme operationalised through Philadelphia community centres. The analysis was performed using a healthcare system perspective in 2013 US dollars. Costs of examination and educational workshops were captured. Measures were total programme costs, cost/case of glaucoma detected and cost/case of any ocular disease detected (including glaucoma). Diagnoses are reported at the individual level (therefore representing a diagnosis made in one or both eyes). Staff time was captured during site visits to 15 of 43 sites and included time to deliver examinations and workshops, supervision, training and travel. Staff time was converted to costs by applying wage and fringe benefit costs from the US Bureau of Labor Statistics. Non-staff costs (equipment and mileage) were collected using study logs. Participants with previously diagnosed glaucoma were excluded. 1649 participants were examined. Mean total per-participant examination time was 56 min (SD 4). Mean total examination cost/participant was $139. The cost/case of glaucoma newly identified (open-angle glaucoma, angle-closure glaucoma, glaucoma suspect, or primary angle closure) was $420 and cost/case for any ocular disease identified was $273. Glaucoma examinations delivered through this programme provided significant health benefit to hard-to-reach communities. On a per-person basis, examinations were fairly low cost, though opportunities exist to improve efficiency. Findings serve as an important benchmark for planning future community-based glaucoma examination programmes. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  4. Allogeneic hematopoietic cell transplantation (allogeneic HCT) for treatment of pediatric Philadelphia chromosome-positive acute lymphoblastic leukemia (ALL).

    Science.gov (United States)

    Burke, Michael J; Cao, Qing; Trotz, Barb; Weigel, Brenda; Kumar, Ashish; Smith, Angela; Verneris, Michael R

    2009-12-15

    Allogeneic hematopoietic cell transplant (HCT) with best available donor for children with Philadelphia positive (Ph+) acute lymphoblastic leukemia (ALL) has previously been considered standard practice. Since the introduction of imatinib into the treatment of this disease, the role of allogeneic HCT is more uncertain. We investigated the impact of remission status, graft source, and imatinib use on transplant outcomes for 37 children with Ph+ ALL who received an allogeneic HCT at the University of Minnesota between 1990 and 2006. The median age at HCT was 7.47 (range; 1.4-16.4) years. Thirteen patients received imatinib therapy pre- and/or post-HCT (imatinib group) and 24 patients, received either no imatinib (n = 23) or only post-HCT relapse (n = 1) (non-imatinib group). There was no difference in disease-free survival (DFS) or relapse between the imatinib and non-imatinib groups at 3 years (62%/15% vs. 53%/26%; P = 0.99; 0.81, respectively). There was no significant difference in transplant outcomes between matched related donor or unrelated donor (umbilical cord blood or matched unrelated marrow) recipients whereas patients receiving allogeneic HCT in first remission (CR1) had superior DFS and less relapse compared to patients transplanted in >or=CR2 (71%/16% vs. 29%/36%; P = 0.01; P = 0.05). Based on this retrospective analysis at a single institution, the use of imatinib either pre- and/or post-transplant does not appear to significantly impact outcomes for children with Ph+ ALL and allogeneic HCT with the best available donor should be encouraged in CR1.

  5. Patient characteristics and outcomes in adolescents and young adults with classical Philadelphia chromosome-negative myeloproliferative neoplasms.

    Science.gov (United States)

    Boddu, Prajwal; Masarova, Lucia; Verstovsek, Srdan; Strati, Paolo; Kantarjian, Hagop; Cortes, Jorge; Estrov, Zeev; Pierce, Sherry; Pemmaraju, Naveen

    2018-01-01

    Little is known about the outcomes of Philadelphia-negative myeloproliferative neoplasms (MPNs) in adolescents and young adults (AYA). We reviewed all patients with essential thrombocythemia (ET), polycythemia vera (PV), and myelofibrosis (MF) treated at our institution from 1988 to 2016 who were aged 16 to 39 years (AYA) and described their outcomes in comparison to older MPN population. Of 2206 patients, 185 (8.3%) were identified as AYA: 105 (57%) ET, 43 (23%) PV, and 37 (20%) MF. The median age was 33 years [range, 16-39], and median follow-up time 3 years [range, 0.04-25]. JAK2 allele burdens were significantly lower among AYA JAK2V617F-mutated patients in both PV (p = 0.001) and MF (p = 0.005). Seven percent of MPN AYA patients were diagnosed with a thrombotic event at, or prior to, diagnosis. Over the short median follow-up, 4 thrombotic (PV = 1, MF = 3) and 3 leukemia (ET = 2, MF = 1) events occurred. In multivariate analysis, AYA did not predict for thrombotic or transformational events across three cohorts. In the MF cohort, there was a reduced frequency of negative prognostic variables of anemia (p = 0.011) and leukocytosis (p = 0.048) in AYA when compared with non-AYA. Overall survival was significantly superior in the AYA cohorts in all three MPN groups, namely MF (p < 0.001), PV (p < 0.001), and ET (p = 0.002). Our findings suggest that MPN AYA patients exhibit an indolent clinical phenotype characterized by favorable survival outcomes.

  6. Electricity derivatives

    CERN Document Server

    Aïd, René

    2015-01-01

    Offering a concise but complete survey of the common features of the microstructure of electricity markets, this book describes the state of the art in the different proposed electricity price models for pricing derivatives and in the numerical methods used to price and hedge the most prominent derivatives in electricity markets, namely power plants and swings. The mathematical content of the book has intentionally been made light in order to concentrate on the main subject matter, avoiding fastidious computations. Wherever possible, the models are illustrated by diagrams. The book should allow prospective researchers in the field of electricity derivatives to focus on the actual difficulties associated with the subject. It should also offer a brief but exhaustive overview of the latest techniques used by financial engineers in energy utilities and energy trading desks.

  7. Electric empire

    International Nuclear Information System (INIS)

    McKay, Paul

    1983-01-01

    The author discusses the economic and political aspects of Ontario Hydro, a provincial crown corporation. He also deals with nuclear safety of the CANDU reactors and the ecological effects of electric power supply. Alternate sources of energy are also mentioned

  8. Electrical Conductivity.

    Science.gov (United States)

    Hershey, David R.; Sand, Susan

    1993-01-01

    Explains how electrical conductivity (EC) can be used to measure ion concentration in solutions. Describes instrumentation for the measurement, temperature dependence and EC, and the EC of common substances. (PR)

  9. Electric theory

    International Nuclear Information System (INIS)

    Gong, Ha Seong

    2006-02-01

    This book explains electric theory which is divided into four chapters. The first chapter includes electricity and material, electric field, capacitance, magnetic field and electromagnetic force, inductance. The second chapter mentions electronic circuit analysis, electric resistance,heating and power, chemical activity on current and battery with electrolysis. The third chapter deals with an alternating current circuit about the basics of an AC circuit, operating of resistance, inductance and capacitance, series circuit and parallel circuit of PLC, an alternating current circuit, Three-phase Alternating current, two terminal pair network and voltage and current of non-linearity circuit. The last explains transient phenomena of RC series circuit, RL series circuit, transient phenomena of an alternating current circuit and transient phenomena of RLC series circuit.

  10. Final environmental statement related to the operation of Limerick Generating Station, Units 1 and 2, Docket Nos. 50-352 and 50-353, Philadelphia Electric Company

    International Nuclear Information System (INIS)

    1989-08-01

    In April 1984 the staff of the Nuclear Regulatory Commission issued its Final Environmental Statement (NUREG-0974) related to the operation of Limerick Generating Station, Units 1 and 2, (Docket Nos. 50-352 and 50-353), located on the Schuylkill River, near Pottstown, in Limerick Township, Montgomery and Chester Counties, Pennsylvania. The NRC has prepared this supplement to NUREG-0974 to present its evaluation of the alternative of facility operation with the installation of further severe accident mitigation design features. The NRC staff has discovered no substantial changes in the proposed action as previously evaluated in the Final Environmental Statement that are relevant to environmental concerns nor significant new circumstances or information relevant to environmental concerns and bearing on the licensing of Limerick Generating Station, Units 1 and 2. 15 refs., 10 tabs

  11. The electric motor handbook

    Energy Technology Data Exchange (ETDEWEB)

    Hurst, R.W.; Feltham, P. (eds.)

    2004-05-01

    This handbook outlines the important role that electric motors play in modern society. It covers the field of motor applications from various motor types to their use and repair. It also presents practical applications of electric motors and methods on motor efficiency. More than half of all electricity generated, and 75 per cent of all industrial electricity consumption is consumed by electric motors. Electrical personnel must be aware of all factors involved in electric motors in order to choose and apply the appropriate size of electric motor. These factors include efficiency, sizing and proper application. The efficient use and maximum life expectancy of electric motors depends on proper motor protection, control and maintenance. This handbook includes articles from leading experts on electric motors in modern electrical systems. The content includes: design considerations; proper electric motor sizing techniques; optimal electric motor application; electric motor protection technology; electric motor control principles; electric motor maintenance and troubleshooting; induction electric motors; electric motor bearing currents; electric motor bearing lubrication; electromagnetism; electric motor enclosures; electric motor testing; electric motor repair; DC electric motor; electric motor starters; electric motor brushes; industrial electric motors; electric motor diagrams; AC electric motors; electric motor wiring; electric motor service; electric motor rewinding; electric motor winding; diagram of electric motor wiring; electric motor kit; and, troubleshooting electric motors. A directory of motor manufacturers and suppliers was also included. refs., tabs., figs.

  12. Electricity saving in households. A social cognitive approach

    Energy Technology Data Exchange (ETDEWEB)

    Thoegersen, John; Groenhoej, Alice [Aarhus University, School of Business and Social Sciences, Department of Marketing, Haslegaardsvej 10, DK-8210 Aarhus (Denmark)

    2010-12-15

    We propose a conceptual framework for understanding the (lack of) energy saving efforts of private households based on Bandura's (1986) social cognitive theory. Results from applying this framework on a sample of Danish private electricity consumers are presented and it is concluded (a) that households' electricity consumption depends on both structural and motivational factors, (b) that their electricity saving effort depends on the strength of their internalized norms or self-expectations and on self-efficacy related factors, and (c) that there are predictable patterns of interaction among household members that influence their electricity consumption. The results suggest two approaches to promote electricity saving in households: (1) to change the socio-structural environment to be more facilitating for energy saving and empower householders to be more effective in their striving towards this goal through improved feedback about their household's electricity consumption and (2) social norms marketing, communicating social expectations and others' successful electricity saving achievements. (author)

  13. Investigation of the Use of Ecodesign Methods and Tools in the Electrical and Electronics Industries of Thailand

    OpenAIRE

    Samuelsson, Erik

    2008-01-01

    This investigation strives to determine the level of ecodesign awareness as well as to map the use of methods and tools for this concept in the electrical and electronics industries of Thailand. The foundation of the thesis is eight semi-structured qualitative research interviews performed with various people at Thai organisations, an electronics manufacturer in Thailand, and experts from Swedish, Danish and Thai universities. The research method has yielded the following results: The level o...

  14. 'Sharing things with people that I don't even know': help-seeking for psychological symptoms in injured Black men in Philadelphia.

    Science.gov (United States)

    Jacoby, Sara F; Rich, John A; Webster, Jessica L; Richmond, Therese S

    2018-04-01

    Psychological distress is common in survivors of traumatic injury, yet across United States' trauma systems, it is rare that standard injury care integrates psychological evaluation and professional mental healthcare. The purpose of this study was to explore help-seeking for psychological symptoms in injured Black men living in Philadelphia. A subset of a cohort of 551 injured Black men admitted to a Trauma Center in Philadelphia participated in qualitative interviews that explored their perceptions of psychological symptoms after injury and the factors that guided their decision to seek professional mental health help. Data from 32 participants were analyzed for narrative and thematic content. Three overarching themes emerged: (1) facilitators of help-seeking, (2) barriers to help-seeking, and (3) factors underlying the decision not to consider professional help. Five participants felt that their injury-related psychological distress was severe enough to merit professional help despite any perceived barriers. Seventeen participants identified systemic and interpersonal obstacles to professional help that prevented them from seeking this kind of care. These included: financial constraints, limited access to mental healthcare services, and fear of the judgments of mental healthcare professionals. Ten participants would not consider professional help; these men perceived a lack of need and sufficiency in their existing social support networks. Research is needed to inform or identify interventions that diminish the impact of barriers to care, and identify from whom, where, and how professional mental health help might be more effectively offered to injured Black men in recovery environments like Philadelphia.

  15. Greengrid Electric

    International Nuclear Information System (INIS)

    Argue, D.

    1998-01-01

    This presentation focused on what customers want from a competitive electricity market and what motivates customers to choose a renewable energy product and service. Greengrid Electric, a subsidiary of Enershare Technology Corp., intends to provide the green electricity that they believe customers have wanted for some time. Enershare and Greengrid have been active participants in the electricity restructuring process in Ontario, and have provided input to the Market Design Committee. Once licensed as a retailer, Greengrid intends to be the major provider of green electricity in Ontario. The company will supply a 100 per cent renewable energy product to their wholesale and retail customers. The company is confident that there is a significant niche market in Ontario for selling a green product that has a blend of wind, small hydro (run-of-river or existing dam), solar, and for energy produced from capturing methane gas from municipal landfill sites. Company officials are confident that customers will be willing to pay a premium price for energy if their purchases will lead to environmental improvement

  16. Striving for the unknown normal

    DEFF Research Database (Denmark)

    Nielsen, Mikka

    During the last decade, more and more people have received prescriptions for ADHD drug treatment, and simultaneously the legitimacy of the ADHD diagnosis has been heavily debated among both professionals and laymen. Based on an anthropological fieldwork among adults with ADHD, I illustrate how...... the ADHD diagnosis both answers and produces existential questions on what counts as normal behaviour and emotions. The diagnosis helps the diagnosed to identify, accept and handle problems by offering concrete explanations and solutions to diffuse experienced problems. But the diagnostic process...... is not only a clarifying procedure with a straight plan for treatment and direct effects. It is also a messy affair. In a process of experimenting with drugs and attempting to determine how or whether the medication eliminates the correct symptoms the diagnosed is put in an introspective, self...

  17. CERN strives to stay ahead

    International Nuclear Information System (INIS)

    Sutton, Christine.

    1987-01-01

    The paper examines the future of CERN, with respect to its proposed research programme and its need to save money. Proposals concerning what accelerators CERN should build for the future are outlined; machines such as the Large Hadron Collider and the CERN Linear Collider have been proposed. Experimental expectations for the first Large Electron Positron (LEP) collider (now close to completion) are briefly described, along with the experimental investigations for the second phase of operation of LEP where modifications will increase the machine's energy. Criticisms of CERN's management by its governing body are also discussed. (UK)

  18. Striving for self-improvement

    DEFF Research Database (Denmark)

    Pedersen, Inge Kryger

    2017-01-01

    The notion of medical enhancement technologies has drawn attention to optimization techniques within the health area. However, this notion has evolved at the level of governmental programmes, with very little attention directed towards people’s own practices. Using a social scientific body...

  19. Striving for Power: Hemingway's Neurosis.

    Science.gov (United States)

    Tavernier-Courbin, Jacqueline

    1978-01-01

    Analyzes the psychological aspects of Ernest Hemingway's inability to accept old age as symptomatic of his neurotic quest for power, which is seen in his drive to excel in pursuits which he thought important, and to take his life when he realized that he was past the peak of his powers. (MB)

  20. ROD meeting: Striving for excellence

    International Nuclear Information System (INIS)

    Taylor, G.M.

    1993-01-01

    At the 16th Reactor Operations International Topical Meeting, held August 15-18, in Melville, Long Island, N.Y., speakers pointed to the continued need to improve the operation of nuclear power plants in the United States. The meeting was sponsored by the American Nuclear Society's Reactor Operations Division and Long Island Local Section. Session speakers pointed out that plant safety is in large measure in the hands of reactor operators independent of the hardware and software in place for reactor operations. Others touched on the economic costs that nuclear energy is facing, compared with coal. Direct labor constitutes 55 percent of the power production costs of nuclear, compared to only 17 percent for coal. The industry has to recognize the opportunity to maximize labor use and reduce costs. Further improving the cost-effectiveness of energy generation will require reducing the dollar investment in plant operation. Speakers proposed reorganizational efforts for the nuclear industry, which will provide a more directed and competitive industry able to compete in todays market

  1. Howell John HARRIS. Bloodless Victories : The Rise and Fall of the Open Shop in the Philadelphia Metal Trades, 1890-1940.

    Directory of Open Access Journals (Sweden)

    Joseph A. McCartin

    2006-03-01

    Full Text Available Howell John Harris’s magisterial history of labor relations in the Philadelphia metal trades has provoked surprisingly little discussion thus far in the United States. Three years after its publication, the book had garnered only a smattering of reviews by labor historians. Indeed, the U.S. journal of record, Labor History, had yet to review the book. Nor had this long-awaited volume by a well-known and passionate participant in U.S. labor historians’ debates drawn the attention of scholarly ...

  2. electric vehicle

    Directory of Open Access Journals (Sweden)

    W. R. Lee

    1999-01-01

    Full Text Available A major problem facing battery-powered electric vehicles is in their batteries: weight and charge capacity. Thus, a battery-powered electric vehicle only has a short driving range. To travel for a longer distance, the batteries are required to be recharged frequently. In this paper, we construct a model for a battery-powered electric vehicle, in which driving strategy is to be obtained such that the total travelling time between two locations is minimized. The problem is formulated as an optimization problem with switching times and speed as decision variables. This is an unconventional optimization problem. However, by using the control parametrization enhancing technique (CPET, it is shown that this unconventional optimization is equivalent to a conventional optimal parameter selection problem. Numerical examples are solved using the proposed method.

  3. Electricity pricing

    International Nuclear Information System (INIS)

    Wijayatunga, P.D.C.

    1994-01-01

    Electricity pricing in most countries, especially in the developing world, has been determined by traditional accounting criteria where it raises revenue requirements to cover the operating costs and a return on past and future capital investments in possible power systems. The use of economic principles to improve the total economic efficiency in the electricity industry is discussed. Basic marginal cost theory, long run marginal costing (LRMC) cost categories and rating periods, marginal capacity costs, marginal energy costs, consumer costs, short run marginal costing (SRMC), marginal cost of fuel, marginal cost of network losses, market clearing price, value of unserved energy and network quality of supply cost are discussed

  4. Small molecule ErbB inhibitors decrease proliferative signaling and promote apoptosis in philadelphia chromosome-positive acute lymphoblastic leukemia.

    Directory of Open Access Journals (Sweden)

    Mary E Irwin

    Full Text Available The presence of the Philadelphia chromosome in patients with acute lymphoblastic leukemia (Ph(+ALL is a negative prognostic indicator. Tyrosine kinase inhibitors (TKI that target BCR/ABL, such as imatinib, have improved treatment of Ph(+ALL and are generally incorporated into induction regimens. This approach has improved clinical responses, but molecular remissions are seen in less than 50% of patients leaving few treatment options in the event of relapse. Thus, identification of additional targets for therapeutic intervention has potential to improve outcomes for Ph+ALL. The human epidermal growth factor receptor 2 (ErbB2 is expressed in ~30% of B-ALLs, and numerous small molecule inhibitors are available to prevent its activation. We analyzed a cohort of 129 ALL patient samples using reverse phase protein array (RPPA with ErbB2 and phospho-ErbB2 antibodies and found that activity of ErbB2 was elevated in 56% of Ph(+ALL as compared to just 4.8% of Ph(-ALL. In two human Ph+ALL cell lines, inhibition of ErbB kinase activity with canertinib resulted in a dose-dependent decrease in the phosphorylation of an ErbB kinase signaling target p70S6-kinase T389 (by 60% in Z119 and 39% in Z181 cells at 3 µM. Downstream, phosphorylation of S6-kinase was also diminished in both cell lines in a dose-dependent manner (by 91% in both cell lines at 3 µM. Canertinib treatment increased expression of the pro-apoptotic protein Bim by as much as 144% in Z119 cells and 49% in Z181 cells, and further produced caspase-3 activation and consequent apoptotic cell death. Both canertinib and the FDA-approved ErbB1/2-directed TKI lapatinib abrogated proliferation and increased sensitivity to BCR/ABL-directed TKIs at clinically relevant doses. Our results suggest that ErbB signaling is an additional molecular target in Ph(+ALL and encourage the development of clinical strategies combining ErbB and BCR/ABL kinase inhibitors for this subset of ALL patients.

  5. Dual-Routine HCV/HIV Testing: Seroprevalence and Linkage to Care in Four Community Health Centers in Philadelphia, Pennsylvania.

    Science.gov (United States)

    Coyle, Catelyn; Kwakwa, Helena

    2016-01-01

    Despite common risk factors, screening for hepatitis C virus (HCV) and HIV at the same time as part of routine medical care (dual-routine HCV/HIV testing) is not commonly implemented in the United States. This study examined improvements in feasibility of implementation, screening increase, and linkage to care when a dual-routine HCV/HIV testing model was integrated into routine primary care. National Nursing Centers Consortium implemented a dual-routine HCV/HIV testing model at four community health centers in Philadelphia, Pennsylvania, on September 1, 2013. Routine HCV and opt-out HIV testing replaced the routine HCV and opt-in HIV testing model through medical assistant-led, laboratory-based testing and electronic medical record modification to prompt, track, report, and facilitate reimbursement for tests performed on uninsured individuals. This study examined testing, seropositivity, and linkage-to-care comparison data for the nine months before (December 1, 2012-August 31, 2013) and after (September 1, 2013-May 31, 2014) implementation of the dual-routine HCV/HIV testing model. A total of 1,526 HCV and 1,731 HIV tests were performed before, and 1,888 HCV and 3,890 HIV tests were performed after dual-routine testing implementation, resulting in a 23.7% increase in HCV tests and a 124.7% increase in HIV tests. A total of 70 currently HCV-infected and four new HIV-seropositive patients vs. 101 HCV-infected and 13 new HIV-seropositive patients were identified during these two periods, representing increases of 44.3% for HCV antibody-positive and RNA-positive tests and 225.0% for HIV-positive tests. Linkage to care increased from 27 currently infected HCV--positive and one HIV-positive patient pre-dual-routine testing to 39 HCV--positive and nine HIV-positive patients post-dual-routine testing. The dual-routine HCV/HIV testing model shows that integrating dual-routine testing in a primary care setting is possible and leads to increased HCV and HIV screening

  6. Long-term evaluation of cardiac and vascular toxicity in patients with Philadelphia chromosome-positive leukemias treated with bosutinib.

    Science.gov (United States)

    Cortes, Jorge E; Jean Khoury, H; Kantarjian, Hagop; Brümmendorf, Tim H; Mauro, Michael J; Matczak, Ewa; Pavlov, Dmitri; Aguiar, Jean M; Fly, Kolette D; Dimitrov, Svetoslav; Leip, Eric; Shapiro, Mark; Lipton, Jeff H; Durand, Jean-Bernard; Gambacorti-Passerini, Carlo

    2016-06-01

    Vascular and cardiac safety during tyrosine kinase inhibitor (TKI) therapy is an emerging issue. We evaluated vascular/cardiac toxicities associated with long-term bosutinib treatment for Philadelphia chromosome-positive (Ph+) leukemia based on treatment-emergent adverse events (TEAEs) and changes in QTc intervals and ejection fraction in two studies: a phase 1/2 study of second-/third-/fourth-line bosutinib for Ph+ leukemia resistant/intolerant to prior TKIs (N = 570) and a phase 3 study of first-line bosutinib (n = 248) versus imatinib (n = 251) in chronic phase chronic myeloid leukemia. Follow-up time was ≥48 months (both studies). Incidences of vascular/cardiac TEAEs in bosutinib-treated patients were 7%/10% overall with similar incidences observed with first-line bosutinib (5%/8%) and imatinib (4%/6%). Few patients had grade ≥3 vascular/cardiac events (4%/4%) and no individual TEAE occurred in >2% of bosutinib patients. Exposure-adjusted vascular/cardiac TEAE rates (patients with events/patient-year) were low for second-line or later bosutinib (0.037/0.050) and not significantly different between first-line bosutinib (0.015/0.024) and imatinib (0.011/0.017; P ≥ 0.267). Vascular/cardiac events were managed mainly with concomitant medications (39%/44%), bosutinib treatment interruptions (18%/21%), or dose reductions (4%/8%); discontinuations due to these events were rare (0.7%/1.0%). Based on logistic regression modelling, performance status >0 and history of vascular or cardiac disorders were prognostic of vascular/cardiac events in relapsed/refractory patients; hyperlipidemia/hypercholesterolemia and older age were prognostic of cardiac events. In newly diagnosed patients, older age was prognostic of vascular/cardiac events; history of diabetes was prognostic of vascular events. Incidences of vascular and cardiac events were low with bosutinib in the first-line and relapsed/refractory settings following long-term treatment in patients

  7. Philadelphia District Laboratory (PHI)

    Data.gov (United States)

    Federal Laboratory Consortium — Program CapabilitiesPHI-DO Pharmaceutical Laboratory specializes in the analyses of all forms and types of drug products.Its work involves nearly all phases of drug...

  8. Electrical Rectification

    Indian Academy of Sciences (India)

    user

    bio-mimetic systems. O w ing to the saturation of the e± ciency of sil- icon devices in electronics industry, m olecular electronics has gained trem endous im petus in re- cent tim es. T heoretical predictions and experi- m ental realizations of such system s have given birth to a ... their electrical conductance property and pos-.

  9. Atmospheric Electricity

    Science.gov (United States)

    Aplin, Karen; Fischer, Georg

    2018-02-01

    Electricity occurs in atmospheres across the Solar System planets and beyond, spanning spectacular lightning displays in clouds of water or dust, to more subtle effects of charge and electric fields. On Earth, lightning is likely to have existed for a long time, based on evidence from fossilized lightning strikes in ancient rocks, but observations of planetary lightning are necessarily much more recent. The generation and observations of lightning and other atmospheric electrical processes, both from within-atmosphere measurements, and spacecraft remote sensing, can be readily studied using a comparative planetology approach, with Earth as a model. All atmospheres contain charged molecules, electrons, and/or molecular clusters created by ionization from cosmic rays and other processes, which may affect an atmosphere's energy balance both through aerosol and cloud formation, and direct absorption of radiation. Several planets are anticipated to host a "global electric circuit" by analogy with the circuit occurring on Earth, where thunderstorms drive current of ions or electrons through weakly conductive parts of the atmosphere. This current flow may further modulate an atmosphere's radiative properties through cloud and aerosol effects. Lightning could potentially have implications for life through its effects on atmospheric chemistry and particle transport. It has been observed on many of the Solar System planets (Earth, Jupiter, Saturn, Uranus, and Neptune) and it may also be present on Venus and Mars. On Earth, Jupiter, and Saturn, lightning is thought to be generated in deep water and ice clouds, but discharges can be generated in dust, as for terrestrial volcanic lightning, and on Mars. Other, less well-understood mechanisms causing discharges in non-water clouds also seem likely. The discovery of thousands of exoplanets has recently led to a range of further exotic possibilities for atmospheric electricity, though lightning detection beyond our Solar System

  10. Electric fields and electrical insulation

    DEFF Research Database (Denmark)

    McAllister, Iain Wilson

    2002-01-01

    The adoption of a field-theoretical approach to problems arising in the framework of electrical insulation is discussed with reference to six main topics, which have been addressed over the last 30 years. These include uniform field electrodes, Green's differential equation, electrode surface...... roughness, induced charge, electrostatic probes, and partial discharge transients, together with several follow-on aspects. Each topic is introduced and thereafter the progress achieved through the use of a field-theoretical approach is reviewed. Because the topics cover a wide spectrum of conditions......, it is amply demonstrated that such an approach can lead to significant progress in many areas of electrical insulation....

  11. Influence of Islamic Traditions on Breastfeeding Beliefs and Practices Among African American Muslims in West Philadelphia: A Mixed-Methods Study.

    Science.gov (United States)

    Kamoun, Camilia; Spatz, Diane

    2018-02-01

    Little is known regarding the influence of religion on breastfeeding in African American communities. In particular, whether Islamic traditions influence breastfeeding beliefs and practices among African American Muslims has not been studied. Research aim: This study sought to gain understanding of breastfeeding attitudes, rates, and education among African American Muslims in West Philadelphia and to examine if engaging Islamic teachings in breastfeeding education can positively influence breastfeeding attitudes. Open-ended, in-person, digitally recorded qualitative interviews were conducted with 10 community leaders and analyzed by conventional content analysis. A study tool distributed to a convenience sample of 44 community members and 11 leaders was used to gather information about education received from community leaders, breastfeeding attitudes and practices, and the potential for Islamic teachings to positively affect breastfeeding attitudes and practices. To obtain further data on this last topic, preliminary data analysis guided the creation of an education pamphlet, about which feedback was gathered through another study tool. Education surrounding Islamic perspectives on breastfeeding was not prevalent. African American Muslims in West Philadelphia view breastfeeding favorably and have higher rates of breastfeeding than African Americans as a whole. Community education about breastfeeding that engaged Islamic teachings improved respondents' breastfeeding attitudes. Increasing education among providers and African American Muslims about Islamic perspectives on breastfeeding may improve breastfeeding exclusivity and duration. Healthcare providers who care for Muslim women should be aware of Islam's tradition of positive attitudes toward breastfeeding and partner with Muslim leaders to improve breastfeeding rates and duration among such women.

  12. Electricity Bill

    International Nuclear Information System (INIS)

    Blair, A.; Beith, A.J.; Hardy, P.

    1989-01-01

    The first part of the debate, which lasted a total of about 7 hours, a verbatim report of the first five of which are included here, was about energy conservation. Several new clauses and amendments were discussed. One would place a duty on the new Director of the Energy Supply industry to promote the efficiency and conservation of energy, another would appoint a Deputy Director with responsibility for energy conservation, and the third would require targets of energy efficiency and pollution reduction to be achieved. This allowed discussion on energy saving by domestic thermal insulation, improved efficiency of heating and refrigeration units and on renewable energy sources especially world energy. The second part of the debate was about access to information regarding health and safety resulting from any activities of the electricity supply industry. The remainder of the debate concerned regional representation and the economics of the electricity supply industry. (UK)

  13. Electricity unplugged

    Science.gov (United States)

    Karalis, Aristeidis

    2009-02-01

    The judge was driving back late one cold winter night. Entering the garage, the battery-charging indicator in his wirelessly powered electric car came on. "Home at last," crossed his mind. He swiped his personal smartcard on the front-door detector to be let in. He heard a "charging" beep from his mobile phone. The blinking cursor on the half-finished e-mail on the laptop had been waiting all day on the side table. He picked the computer up and walked towards his desk. "Good evening, your honour. Your wirelessly heated robe," said the butler-robot as it approached from the kitchen. Putting on the electric garment, he sat on the medical desk chair. His artificial heart was now beating faster.

  14. Electricity supply

    International Nuclear Information System (INIS)

    Rezendes, V.S.

    1991-10-01

    This report focuses on the Securities and Exchange Commission's (SEC) administration of the Public Utility Holding Company Act of 1935, intended to protect the public, investors, and consumers from abuses associated with the control of electric and gas utility companies through the holding company structure. These abuses include subjecting subsidiary utilities to excessive charges for services, construction work, and materials; frustrating effective state regulation through the holding company structure; and overloading subsidiary utilities with debt to prevent voluntary rate reductions. GAO discusses industry changes during the past decade involving electric utility holding companies; SEC's regulatory response to such changes; and the relationship between SEC, the Federal Energy Regulatory Commission, and states in protecting consumer and investor interests in light of these changes

  15. Electrical generator

    International Nuclear Information System (INIS)

    Purdy, D.L.

    1976-01-01

    A nuclear heart pacer having a heat-to-electricity converter including a solid-state thermoelectric unit embedded in rubber which is compressed to impress hydrostatic precompression on the unit is described. The converter and the radioactive heat source are enclosed in a container which includes the electrical circuit components for producing and controlling the pulses; the converter and components being embedded in rubber. The portions of the rubber in the converter and in the container through which heat flows between the radioactive primary source and the hot junction and between the cold junction and the wall of the container are of thermally conducting silicone rubber. The 238 Pu primary radioactive source material is encapsuled in a refractory casing of WC-222 (T-222) which in turn is encapsuled in a corrosion-resistant casing of platinum rhodium, a diffusion barrier separating the WC-222 and the Pt--Rh casings. The Pt--Rh casing is in a closed basket of tantalum. The tantalum protects the Pt--Rh from reacting with other materials during cremation of the host, if any. The casings and basket suppress the transmission of hard x rays generated by the alpha particles from the 238 Pu. The outside casing of the pacer is typically of titanium but its surface is covered by an electrically insulating coating, typically epoxy resin, except over a relatively limited area for effective electrical grounding to the body of the host. It is contemplated that the pacer will be inserted in the host with the exposed titanium engaging a non-muscular region of the body

  16. Electric Car

    Science.gov (United States)

    1977-01-01

    NASA's Lewis Research Center undertook research toward a practical, economical battery with higher energy density. Borrowing from space satellite battery technology, Lewis came up with a nickel-zinc battery that promises longer life and twice the range of the lead-acid counterpart. Lewis researchers fabricated a prototype battery and installed it in an Otis P-500 electric utility van, using only the battery space already available and allowing battery weight equal to that of the va's conventional lead-acid battery

  17. Electrical deregulation

    International Nuclear Information System (INIS)

    Simpson, R.

    2001-01-01

    Deregulation in the electricity sector took effect on January 1, 2001 in Alberta. Business consumers discovered that their electricity rates had almost doubled in a one-month period. The government argued that it was the case of short term pain for long term gain. The intent of the deregulation is the lowering of prices through competition. This principle applies when the supply meets the demand, but when the demand exceeds the supply, prices increase. When initial plans were made for the deregulation of the sector, utilities did not invest huge amounts of capital to build new generation plants, as it was not known how they would fare in the deregulated environment. This situation was compounded by the fact that there was an economic boom around the same time in Alberta, adding to the demands made on the existing generation infrastructure (approximately 4 per cent per year over the past decade). At the moment, some resource developers such as Syncrude, Amoco, and Daishowa produce their own electricity and export their excess capacity to the provincial grid for general use. The rules of the deregulated market have been clarified and a number of utilities are planning new generation plants and facilities. TransAlta, EPCOR, and Enmax Corp. have announced plans to expand or build new coal-fired plants. Alberta has an estimated 35 billion tonnes of recoverable coal, and 25 million tonnes of coal were used in 1999 to produce 75 per cent of the electricity required in Alberta. Over the next ten years, 4,000 megawatts of new capacity is planned, representing a 50 per cent increase over current levels. AES Corporation, a Virginia power giant, has also announced plans to build a generator in Alberta

  18. Electrical cardioversion

    Science.gov (United States)

    Sucu, Murat; Davutoglu, Vedat; Ozer, Orhan

    2009-01-01

    External electrical cardioversion was first performed in the 1950s. Urgent or elective cardioversions have specific advantages, such as termination of atrial and ventricular tachycardia and recovery of sinus rhythm. Electrical cardioversion is life-saving when applied in urgent circumstances. The succcess rate is increased by accurate tachycardia diagnosis, careful patient selection, adequate electrode (paddles) application, determination of the optimal energy and anesthesia levels, prevention of embolic events and arrythmia recurrence and airway conservation while minimizing possible complications. Potential complications include ventricular fibrillation due to general anesthesia or lack of synchronization between the direct current (DC) shock and the QRS complex, thromboembolus due to insufficient anticoagulant therapy, non-sustained VT, atrial arrhythmia, heart block, bradycardia, transient left bundle branch block, myocardial necrosis, myocardial dysfunction, transient hypotension, pulmonary edema and skin burn. Electrical cardioversion performed in patients with a pacemaker or an incompatible cardioverter defibrillator may lead to dysfunction, namely acute or chronic changes in the pacing or sensitivity threshold. Although this procedure appears fairly simple, serious consequences might occur if inappropriately performed. PMID:19448376

  19. evaluation of electricity consumer's behaviour towards electricity ...

    African Journals Online (AJOL)

    Energy efficiency and sustainability: evaluation of electricity consumer's behaviour towards electricity usage and energy conservation. ... Remember me ... particularly about electricity consumer's attitudes, behaviour and practices with respect ...

  20. Minorities Striving and Pursuing Higher Degrees of Success in Earth System Science (MS PHD'S) Beyond the PhD Professional Development Program: A Pilot Project

    Science.gov (United States)

    Johnson, A.; Jearld, A.; Williamson Whitney, V.; Huggans, M.; Ricciardi, L.; Thomas, S. H.; Jansma, P. E.

    2012-12-01

    In 2011 the Minorities Striving and Pursuing Higher Degrees of Success in Earth System Science (MS PHD'S)® initiative launched its newest activity entitled the MS PHD'S "Beyond the PhD (B-PhD) Professional Development Program." This exciting new program was designed to facilitate the development of a new community of underrepresented minority (URM) doctoral candidates and recent doctorate degree recipients in Earth system science (ESS)-related fields. The MS PHD'S B-PhD provides customized support and advocacy for MS PHD'S B-PhD participants in order to facilitate smoother and informed transitions from graduate school, to postdoctoral and tenure-track positions, as well as other "first" jobs in government, industry, and non-profit organizations. In November 2011 the first cohort of MS PHD'S B-PhD participants engaged in intensive sessions on the following topics: "Toolkits for Success for Academia, Business/Industry, Federal Government and Non-Profits", "Defining Short, Mid and Long Term Career Goals", "Accessing and Refining Skill Sets and Other Door Openers", "International Preparation and Opportunities", "Paying it Forward/Lifting as You Climb", and "Customized Strategies for Next Steps". This pilot event, which was hosted by the University of Texas at Arlington's (UTA) College of Science, also provided opportunities for participants to serve as guest lecturers in the UTA's Colleges of Science and Engineering and included one-on-one discussions with MS PHD'S B-PhD mentors and guest speakers who are well established within their individual ESS fields. Insights regarding opportunities, challenges and obstacles commonly faced by URMs within the ESS fields, as well as strategies for success were shared by MS PHD'S B-PhD mentors and guest speakers. Survey results indicate that MS PHD'S B-PhD participants appreciated not only the material covered during this pilot activity, but also appreciated the opportunity to become part of a community of young URM ESS

  1. Electrical transmission

    Energy Technology Data Exchange (ETDEWEB)

    Sayers, D P

    1960-05-01

    After briefly tracing the history of electricity transmission, trends in high voltage transmission and experiments being conducted on 650 kV are discussed. 5000 miles of the U.K. grid are operated at 132 kV and 1000 at 275 kV, ultimately to provide a super grid at 380 kV. Problems are insulation, radio interference and the cost of underground lines (16 times that of overhead lines). Also considered are the economics of the grid as a means of transporting energy and as a means of spreading the peak load over the power stations in the most efficient manner. Finally, the question of amenities is discussed.

  2. Electric rivers

    International Nuclear Information System (INIS)

    McCutcheon, S.

    1992-04-01

    James Bay II, the projected Canadian hydroelectric power plant of gigantic dimensions, is to deliver its electricity to Europe: in the USA, opposition to power imports from James Bay is growing. Its realization means the flooding of an area as big as the Federal Republic of Germany; the native territory and hunting grounds of the Cree indians would be inundated. The interests of the European power industry in the James Bay project and the consequences for Europe are described in an appendix (EQHHPP project, project management Hydro-Quebec and Ludwig Boelkow Foundation, hydrogen production through electrolysis, methods for transporting hydrogen to Hamburg). (orig./HP) [de

  3. Section 2: Case Studies of the Politics of Privatization: Bringing the Private into the Public--Changing the Rules of the Game and New Regime Politics in Philadelphia Public Education

    Science.gov (United States)

    Bulkley, Katrina E.

    2007-01-01

    Substantial policy and political changes have resulted from a 2001 state takeover of the Philadelphia School District and the subsequent hiring of Paul Vallas as the district's new CEO. Using the lens of urban regime analysis, which emphasizes the importance of public and private actors in forming a governing coalition, this article analyzes the…

  4. Comparison of imatinib 400 mg and 800 mg daily in the front-line treatment of high-risk, Philadelphia-positive chronic myeloid leukemia: a European LeukemiaNet Study

    DEFF Research Database (Denmark)

    Baccarani, Michele; Rosti, Gianantonio; Castagnetti, Fausto

    2009-01-01

    Imatinib mesylate (IM), 400 mg daily, is the standard treatment of Philadelphia-positive (Ph(+)) chronic myeloid leukemia (CML). Preclinical data and results of single-arm studies raised the suggestion that better results could be achieved with a higher dose. To investigate whether the systematic...

  5. [Electrical storm].

    Science.gov (United States)

    Barnay, C; Taieb, J; Morice, R

    2007-11-01

    Electrical storm is defined as repeated occurrence of severe ventricular arrhythmias requiring multiple cardioversions, two or more or three or more following different studies. The clinical aspect can sometimes be made of multiple, self aggravating, life threatening accesses. There are three main clinical circumstances of occurrence: in patients equipped with intracardiac defibrillators, during the acute phase of myocardial infarction and in Brugada syndrome. 10 to 15% of patients with cardiac defibrillators are subject to electrical storms in a period of two years. The causative arrhythmia is most often ventricular tachycardia than ventricular fibrillation, especially in secondary prevention and if the initial arrhythmias justifying the device was a ventricular tachycardia. Precipitaing factors are present in one third of cases, mainly acute heart failure, ionic disorders and arrhythmogenic drugs. Predictive factors are age, left ventricular ejection fractionelectrical shock in 50% of cases, antitachycardi stimulation in 30% and in 20% by association of the two. Treatment, after elimination of inappropriate shocks, is mainly based on beta-blockers and amiodarone, class I antiarrhythmics, lidocaïne or bretylium in some cases, and sedation pushed to general anesthesia in some cases. Radio-frequency ablation and even heart transplantation have been proposed in extreme cases. Quinidine has been proved efficient in cases of Brugada syndrome.

  6. Electric crossover

    International Nuclear Information System (INIS)

    Schuster, R.M.; Luria, N.G.

    1977-01-01

    This invention concerns an electric crossover that makes a steam and pressure-tight seal for a conductor crossing two separate walls of a nuclear reactor vessel that seismic tremors or thermal expansion of the walls and conductor subject to relative displacements. The conductors, that have to cross the vessels, are fixed to the walls of the vessel in crossover systems fitted in crossover channels made in the walls of the vessel on their initial manufacture. The separate walls of the vessel move independently when they undergo an earth tremor or a temperature change between the walls or between the conductor. This shift can damage the conductor or the crossover system and this could give rise to cause steam or other materials to leak in the reactor should leaks occur in the primary system. Furthermore, in the case of medium or high power conductors, which are relatively rigid, the non-alignment of the crossover channels can bring about awkward stresses in the conductors or their protective sheathing. The aims of this invention are fulfilled by designing an electric crossover to pass at least one conductor through the two separate walls of a vessels, that includes an initial sub-assembly crossover, secured in a leak-tight manner to the first wall and a second sub-sessembly crossover in sliding or rolling contact with the second wall, whilst forming a leak-tight seal with it [fr

  7. Electric-Drive Vehicles

    Energy Technology Data Exchange (ETDEWEB)

    Septon, Kendall K [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2017-09-11

    Electric-drive vehicles use electricity as their primary fuel or to improve the efficiency of conventional vehicle designs. These vehicles can be divided into three categories: Hybrid electric vehicles (HEVs), Plug-in hybrid electric vehicles (PHEVs), All-electric vehicles (EVs). Together, PHEVs and EVs can also be referred to as plug-in electric vehicles (PEVs).

  8. Electric-Drive Vehicles

    Energy Technology Data Exchange (ETDEWEB)

    None

    2017-09-01

    Electric-drive vehicles use electricity as their primary fuel or to improve the efficiency of conventional vehicle designs. These vehicles can be divided into three categories: Hybrid electric vehicles (HEVs), Plug-in hybrid electric vehicles (PHEVs), All-electric vehicles (EVs). Together, PHEVs and EVs can also be referred to as plug-in electric vehicles (PEVs).

  9. CD20 positivity and white blood cell count predict treatment outcomes in Philadelphia chromosome-negative acute lymphoblastic leukemia patients ineligible for pediatric-inspired chemotherapy.

    Science.gov (United States)

    Isshiki, Yusuke; Ohwada, Chikako; Sakaida, Emiko; Onoda, Masahiro; Aotsuka, Nobuyuki; Tanaka, Hiroaki; Fukazawa, Motoharu; Cho, Ryuko; Sugawara, Takeaki; Kawaguchi, Takeharu; Hara, Satoru; Yokota, Akira

    2017-11-01

    The efficacy of conventional chemotherapy and allogeneic hematopoietic stem cell transplantation (allo-HSCT) has been controversial as post-remission therapies for adult Philadelphia chromosome-negative acute lymphoblastic leukemia patients. We retrospectively analyzed 96 adolescent and adult cases of Philadelphia chromosome-negative acute lymphoblastic leukemia to evaluate whether allo-HSCT should be performed after first complete remission (1CR). In total, 34 patients received chemotherapy followed by allo-HSCT (HSCT group) and 62 received chemotherapy alone (chemotherapy group). No significant differences in the event-free survival (EFS) or overall survival were observed between the two groups. In the chemotherapy group, use of pediatric regimens was significantly associated with favorable EFS, while high white blood cell (WBC) count and CD20 positivity were associated with poor outcome. In patients who received pediatric regimens, subsequent allo-HSCT did not influence EFS. In patients who received conventional chemotherapy (adult regimen), subsequent allo-HSCT did not improve EFS. High WBC count and CD20 positivity were also significantly associated with poor EFS in patients who received adult regimens. Patients with low WBC count and absence of CD20 who received adult regimens did not benefit from allo-HSCT. Allo-HSCT may not be required in the pediatric regimen-eligible patients; however, pediatric regimen-ineligible patients with either CD20 positivity or high WBC count should receive allo-HSCT after achieving 1CR. This study was registered at http://www.umin.ac.jp/ctr/ as #C000016287. © The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

  10. Fine-scale spatial variability of heat-related mortality in Philadelphia County, USA, from 1983-2008: a case-series analysis

    Directory of Open Access Journals (Sweden)

    Hondula David M

    2012-03-01

    Full Text Available Abstract Background High temperature and humidity conditions are associated with short-term elevations in the mortality rate in many United States cities. Previous research has quantified this relationship in an aggregate manner over large metropolitan areas, but within these areas the response may differ based on local-scale variability in climate, population characteristics, and socio-economic factors. Methods We compared the mortality response for 48 Zip Code Tabulation Areas (ZCTAs comprising Philadelphia County, PA to determine if certain areas are associated with elevated risk during high heat stress conditions. A randomization test was used to identify mortality exceedances for various apparent temperature thresholds at both the city and local scale. We then sought to identify the environmental, demographic, and social factors associated with high-risk areas via principal components regression. Results Citywide mortality increases by 9.3% on days following those with apparent temperatures over 34°C observed at 7:00 p.m. local time. During these conditions, elevated mortality rates were found for 10 of the 48 ZCTAs concentrated in the west-central portion of the County. Factors related to high heat mortality risk included proximity to locally high surface temperatures, low socioeconomic status, high density residential zoning, and age. Conclusions Within the larger Philadelphia metropolitan area, there exists statistically significant fine-scale spatial variability in the mortality response to high apparent temperatures. Future heat warning systems and mitigation and intervention measures could target these high risk areas to reduce the burden of extreme weather on summertime morbidity and mortality.

  11. Electricity privatisation

    International Nuclear Information System (INIS)

    Dobson, Frank; Skinner, Dennis; Marshall, John

    1990-01-01

    In this amendment debate about the privatisation of the electricity supply, the opposition develops a number of themes detracting from the government's policy in this matter. It is felt that the industry is being sold off much too cheaply, at about one third of its value based on previous audits. Measures to prevent environmental damage are not likely to be implemented as they would reduce profits. Fuel reserves are in danger of depletion, especially natural gas. Coal imports will increase with accompanying threats to the balance of payments. Lastly, it is argued that very large sums of money are being paid unnecessarily to City Analysts and that big business and M.P.s are acting immorally in extracting money from what should be a publicly owned utility. The amendment was defeated by 298 to 186. (author)

  12. Thermal Management of Battery Systems in Electric Vehicle and Smart Grid Application

    DEFF Research Database (Denmark)

    Khan, Mohammad Rezwan

    vehicles is foreseen. The future battery manufacturers strive to meet the ever growing requirement of consumer’s demand using the battery as a primary power source of these cars. So naturally, the growing popularity of battery electric and hybrid vehicles have catapulted the car industry in the recent......Last few years’ governments are tightening the carbon emission regulations. Moreover, the availability of different financial assistances is available to cut the market share of the fossil fuel vehicles. Conversely, to fill up the gap of the required demand, higher penetration of electrical...... years. The products include for instance: hybrids, plug-in hybrids, battery and fuel-cell-battery electric vehicles (EV) and so forth. Undeniably, the battery is one of the most significant parts in all of those. Furthermore, stationary storage is another aspect of an emerging field. It represents next...

  13. Towards sustained Innovation in Education using Design-Based-Research - A new Approach to Teaching Electricity

    CERN Multimedia

    CERN. Geneva

    2018-01-01

    The influence of Physics Education Research (PER) on teaching in schools is often rather limited. Design-Based-Research tries to overcome this often-criticised research-practice gap by developing and evaluating new approaches to teaching physics. Using a variety of qualitative and quantitative research methods and working closely with schools, design research strives to find evidence-based solutions to pressing educational problems. One such problem in physics education is that most students fail to correctly analyse electric circuits even after instruction as they tend to reason exclusively with current and resistance. Effective reasoning about electric circuits, however, requires a solid understanding of voltage and potential. At the example of the development and evaluation of an innovative curriculum to teach electricity based on the electron gas model, the presentation will give an introduction to Design-Based-Research in PER.

  14. Proceedings of the Annual Symposium on Frequency Control (38th) Held in Philadelphia, Pennsylvania on 29 May - 1 June 1984

    Science.gov (United States)

    1984-06-01

    the sodium concentration showed strong electric field/temperature levels. correlation with the density of color-center absorption. Aluminium levels are... THERMOMETRIC QUARTZ CUTS _3 * 0 0 $= ~ ~ o- ,; = e -1o’. 95 ~N. km j,(0 20. 20. a 6.264 4.4 6.0 1.6 b 2.090 7.5 2.0 2,8 NLSC 1 1.695 4.2 10.5 1 .6 11.17...deplacement Half wave resonators can be obtained as shown in pic- of an aluminium disc. ture 3, that is to say in opened network with L = A g ; the resonator

  15. Electrical equipment design library

    International Nuclear Information System (INIS)

    1994-01-01

    This book guides the design supervision, construction order for electrical equipment. The contents of this library are let's use electricity like this, leading-in-pole and casual power, electric pole install below 300KVA, electric pole install below 301∼1000KVA, electric pole install exceed 1000KVA, rooftop install exceed 1000KVA, CUBICLE type, 154KV services. It adds an appendix.

  16. Impact of driving cycle and climate on electrical consumption and range of a fully electric passenger vehicle

    Energy Technology Data Exchange (ETDEWEB)

    Meyer, N; Belzile, M [Transport Canada, Ottawa, ON (Canada); Christenson, M; Edgar, J [Environment Canada, Gatineau, PQ (Canada)

    2010-07-01

    Transport Canada's ecotechnology for vehicles (eTV) program is a $15 million program, operated over 4 years (2007-2011) that strives to encourage the introduction of advanced clean vehicle technologies in Canada. The objectives of eTV's are to reduce barriers to the introduction of clean technologies into light-duty vehicles sold in Canada. The presentation discussed the mandate of the emissions research and measurement section of Environment Canada. The dynamometer test facility, a state-of-the-art emissions testing laboratory capable of conducting comprehensive emissions measurements from a variety of sources was also discussed. Several electric mobility projects were presented. The testing rationale and testing outline were explained. It was concluded that the repeatability of cold tests appeared to be similar to the repeatability of ambient tests. tabs., figs.

  17. Impact of driving cycle and climate on electrical consumption and range of a fully electric passenger vehicle

    Energy Technology Data Exchange (ETDEWEB)

    Meyer, N.; Belzile, M. [Transport Canada, Ottawa, ON (Canada); Christenson, M.; Edgar, J. [Environment Canada, Gatineau, PQ (Canada)

    2010-07-01

    Transport Canada's ecotechnology for vehicles (eTV) program is a $15 million program, operated over 4 years (2007-2011) that strives to encourage the introduction of advanced clean vehicle technologies in Canada. The objectives of eTV's are to reduce barriers to the introduction of clean technologies into light-duty vehicles sold in Canada. The presentation discussed the mandate of the emissions research and measurement section of Environment Canada. The dynamometer test facility, a state-of-the-art emissions testing laboratory capable of conducting comprehensive emissions measurements from a variety of sources was also discussed. Several electric mobility projects were presented. The testing rationale and testing outline were explained. It was concluded that the repeatability of cold tests appeared to be similar to the repeatability of ambient tests. tabs., figs.

  18. The Electric Car Challenge.

    Science.gov (United States)

    Diehl, Brian E.

    1997-01-01

    Describes the Electric Car Challenge during which students applied methods of construction to build lightweight, strong vehicles that were powered by electricity. The activity required problem solving, sheet metal work, electricity, design, and construction skills. (JOW)

  19. Electrical Methods: Resistivity Methods

    Science.gov (United States)

    Surface electrical resistivity surveying is based on the principle that the distribution of electrical potential in the ground around a current-carrying electrode depends on the electrical resistivities and distribution of the surrounding soils and rocks.

  20. Controlling Electrical Hazards

    National Research Council Canada - National Science Library

    1997-01-01

    ...). In general, OSHA's electrical standards are based on the National Fire Protection Associations Standard NFPA 70E, Electrical Safety Requirements for Employee Workplaces, and in turn, from the National Electrical Code (NEC...

  1. Agricultural Electricity. Electric Motors. Student Manual.

    Science.gov (United States)

    Benson, Robert T.

    Addressed to the student, this manual, which includes supplementary diagrams, discusses the following topics and principles: Electromagnetic fields, electromagnets, parts of an electric motor, determining speed of an electric motor, types of electric motors in common use (split-phase, capacitor, repulsion-induction, three-phase), the electric…

  2. Prices on electricity and transmission of electricity

    International Nuclear Information System (INIS)

    2003-01-01

    This publication contains data on prices of electric energy and transmission of electricity valid from 1 January 2003. The purpose is to illustrate the price changes on the electricity market in terms of prices for different customer categories. All companies holding network concessions for areas and all companies trading in electricity are included in this report, which is produced on an annual basis.The prices for transmission services 1 January 2003 were on the whole unchanged compared to the preceding year. For households the mean annual cost was SEK 882 for flats, SEK 4 335 for one- or two-family houses with electric heating and SEK 1 925 for those without electric heating. Electricity prices rose considerably on 1 January 2003 compared to the year before. The mean price per kWh for households with standard agreements was SEK 0.519 for deliveries to flats, SEK 0.447 for one- or two-family houses with electric heating and SEK 0.471 without electric heating. As a result, the mean annual cost increased by SEK 326 for flats, SEK 3 012 for one- or two-family houses with electric heating, and by SEK 774 for those houses without electric heating. The high costs of electricity may be explained in part by the development on the Nordic Power Exchange (Nord Pool), where the spot price increased by about 290 per cent during 2002 (1 USD is about 8 SEK)

  3. Electrical engineer's reference book

    CERN Document Server

    Laughton, M A

    1985-01-01

    Electrical Engineer's Reference Book, Fourteenth Edition focuses on electrical engineering. The book first discusses units, mathematics, and physical quantities, including the international unit system, physical properties, and electricity. The text also looks at network and control systems analysis. The book examines materials used in electrical engineering. Topics include conducting materials, superconductors, silicon, insulating materials, electrical steels, and soft irons and relay steels. The text underscores electrical metrology and instrumentation, steam-generating plants, turbines

  4. DOE handbook electrical safety

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-01-01

    Electrical Safety Handbook presents the Department of Energy (DOE) safety standards for DOE field offices or facilities involved in the use of electrical energy. It has been prepared to provide a uniform set of electrical safety guidance and information for DOE installations to effect a reduction or elimination of risks associated with the use of electrical energy. The objectives of this handbook are to enhance electrical safety awareness and mitigate electrical hazards to employees, the public, and the environment.

  5. Electrical safety guidelines

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-01

    The Electrical Safety Guidelines prescribes the DOE safety standards for DOE field offices or facilities involved in the use of electrical energy. It has been prepared to provide a uniform set of electrical safety standards and guidance for DOE installations in order to affect a reduction or elimination of risks associated with the use of electrical energy. The objectives of these guidelines are to enhance electrical safety awareness and mitigate electrical hazards to employees, the public, and the environment.

  6. The health status and well-being of low-resource, housing-unstable, single-parent families living in violent neighbourhoods in Philadelphia, Pennsylvania.

    Science.gov (United States)

    Jacoby, Sara F; Tach, Laura; Guerra, Terry; Wiebe, Douglas J; Richmond, Therese S

    2017-03-01

    The health and well-being of single-parent families living in violent neighbourhoods in US cities who participate in housing programmes is not well described. This two-phase, mixed-methods study explores the health status of families who were participants in a housing-plus programme in Philadelphia, Pennsylvania between 2011 and 2013 and the relationship between the characteristics of the neighbourhoods in which they lived and their perceptions of well-being and safety. In phase 1, data collected with standardised health status instruments were analysed using descriptive statistics and independent sample t-tests to describe the health of single parents and one randomly selected child from each parent's household in comparison to population norms. In a subset of survey respondents, focus groups were conducted to generate an in-depth understanding of the daily lives and stressors of these families. Focus group data were analysed using content analysis to identify key descriptive themes. In phase 2, daily activity path mapping, surveys and interviews of parent-child dyads were collected to assess how these families perceive their health, neighbourhood and the influence of neighbourhood characteristics on the families' day-to-day experience. Narratives and activity maps were combined with crime data from the Philadelphia Police Department to analyse the relationship between crime and perceptions of fear and safety. Phase 1 data demonstrated that parent participants met or exceeded the national average for self-reported physical health but fell below the national average across all mental health domains. Over 40% reported moderate to severe symptoms of depression. Parents described high levels of stress resulting from competing priorities, financial instability, and concern for their children's well-being and safety. Analysis of phase 2 data demonstrated that neighbourhood characteristics exert influence over parents' perceptions of their environment and how they permit

  7. Prognostic significance of ASXL1, JAK2V617F mutations and JAK2V617F allele burden in Philadelphia-negative myeloproliferative neoplasms

    Directory of Open Access Journals (Sweden)

    Yonal-Hindilerden I

    2015-06-01

    Full Text Available Ipek Yonal-Hindilerden, Aynur Daglar-Aday, Basak Akadam-Teker, Ceylan Yilmaz, Meliha Nalcaci, Akif Selim Yavuz, Deniz SarginDivision of Hematology, Department of Internal Medicine, Istanbul Medical Faculty, Istanbul University, Fatih-Istanbul, Turkey Background: Despite insights into the genetic basis of Philadelphia-negative myeloproliferative neoplasms (Ph-negative MPNs, a significant proportion of essential thrombocythemia (ET and primary myelofibrosis (PMF patients present with no known MPN disease alleles. There were no previous studies investigating the impact of ASXL1 mutations in Ph-negative MPNs in Turkey. In the current study, we investigated the prognostic significance of ASXL1 mutations in Turkish MPN patients. We also aimed to determine the prognostic significance of JAK2V617F allele burden and the relationship of JAK2V617F mutation with ASXL1 mutations in Ph-negative MPNs. Methods: About 184 patients from a single center diagnosed with Ph-negative MPNs were screened for ASXL1, JAK2V617F mutations, and JAK2V617F allele burden: 107 ET and 77 PMF. Results: A total of 29 ASXL1 mutations were detected in 24.7% of PMF and 8.4% of ET patients. ASXL1-mutated ET patients showed a trend toward an increase in the incidence of cerebrovascular events and higher total leukocyte counts. ASXL1-mutation in PMF was associated with older age and a higher prevalence of bleeding complications. In univariate analysis, overall survival (OS was significantly reduced in ASXL1-mutated PMF patients. In multivariate analysis, Dynamic International Prognostic Scoring System-plus high-risk category and ASXL1 mutation status were independently associated with shorter survival in PMF. In PMF, mutational status and allele burden of JAK2V617F showed no difference in terms of OS and leukemia-free survival. Conclusion: We conclude that ASXL1 mutations are molecular predictors of short OS in PMF. Keywords: Philadelphia-negative myeloproliferative neoplasms (Ph

  8. Electric engineering introduction

    International Nuclear Information System (INIS)

    An, Byeong Won; Eom, Sang Ho

    1999-03-01

    It is divided into nine chapters, which includes electricity theory such as structure of material and current, nature of electricity, static, magnetic force and magnetic attraction, attraction of current and a storage battery, electric circuit on a direct current circuit, single phase circuit and 3-phase current circuit electricity machine like DC generator, DC motor, alternator, electric transformer, single-phase induction motor, 3-phase induction motor, synchronous motor, synchro electric machine, semiconductor such as diode, transistor, FET, UJT, silicon symmetrical switch, electronic circuit like smoothing circuit and Bistable MV. circuit, automatic control, measurement of electricity, electric application and safety.

  9. Striving to maintain a dignified life for the patient in transition: Next of kin’s experiences during the transition process of an older person in transition from hospital to home

    Directory of Open Access Journals (Sweden)

    Sigrun Hvalvik

    2015-03-01

    Full Text Available Next of kin represent significant resources in the care for older patients. The aim of this study was to describe and illuminate the meaning of the next of kin’s experiences during the transition of an older person with continuing care needs from hospital to home. The study has a phenomenological hermeneutic design. Individual, narrative interviews were conducted, and the data analysis was conducted in accordance with Lindseth and Norberg’s phenomenological hermeneutic method. Two themes and four subthemes were identified and formulated. The first theme: “Balancing vulnerability and strength,” encompassed the subthemes “enduring emotional stress” and “striving to maintain security and continuity.” The second theme: “Coping with an altered everyday life,” encompassed “dealing with changes” and “being in readiness.” Our findings suggest that the next of kin in striving to maintain continuity and safety in the older person’s transition process are both vulnerable individuals and significant agents. Thus, it is urgent that health care providers accommodate both their vulnerability and their abilities to act, and thereby make them feel valued as respected agents and human beings in the transition process.

  10. Safety and efficacy of combination therapy of interferon-alpha2 + JAK1-2 Inhibitor in the philadelphia-negative chronic myeloproliferative neoplasms. Preliminary results from the danish combi-trial-an open label, single arm, non-randomized multicenter phase II study

    DEFF Research Database (Denmark)

    Mikkelsen, S. U.; Kjaer, L.; Skov, V.

    2015-01-01

    Background: The Philadelphia-negative, chronic myeloproliferative neoplasms (MPN) include essential thrombocythemia (ET), polycythemia vera (PV) and primary myelofibrosis (MF) (PMF). Chronic inflammation and a deregulated immune system are considered important for clonal evolution and disease...

  11. Assessment of contamination and misclassification biases in a randomized controlled trial of a social network peer education intervention to reduce HIV risk behaviors among drug users and risk partners in Philadelphia, PA and Chiang Mai, Thailand.

    Science.gov (United States)

    Simmons, Nicole; Donnell, Deborah; Ou, San-San; Celentano, David D; Aramrattana, Apinun; Davis-Vogel, Annet; Metzger, David; Latkin, Carl

    2015-10-01

    Controlled trials of HIV prevention and care interventions are susceptible to contamination. In a randomized controlled trial of a social network peer education intervention among people who inject drugs and their risk partners in Philadelphia, PA and Chiang Mai, Thailand, we tested a contamination measure based on recall of intervention terms. We assessed the recall of test, negative and positive control terms among intervention and control arm participants and compared the relative odds of recall of test versus negative control terms between study arms. The contamination measures showed good discriminant ability among participants in Chiang Mai. In Philadelphia there was no evidence of contamination and little evidence of diffusion. In Chiang Mai there was strong evidence of diffusion and contamination. Network structure and peer education in Chiang Mai likely led to contamination. Recall of intervention materials can be a useful method to detect contamination in experimental interventions.

  12. Busulfan is effective second-line therapy for older patients with Philadelphia-negative myeloproliferative neoplasms intolerant of or unresponsive to hydroxyurea.

    Science.gov (United States)

    Douglas, Genevieve; Harrison, Claire; Forsyth, Cecily; Bennett, Michael; Stevenson, William; Hounsell, John; Ratnasingam, Sumita; Ritchie, David; Ross, David M; Grigg, Andrew

    2017-01-01

    Hydroxyurea (Hu) is widely used as first-line cytoreductive therapy for patients with high-risk Philadelphia-negative myeloproliferative neoplasms (Ph-neg MPN), but a small proportion of patients have refractory disease or experience adverse effects. Studies have demonstrated busulfan (Bu) to be an active first-line agent, but data on its role as second-line or later therapy are minimal. To evaluate its efficacy and safety in this context, we undertook a multicenter audit of Ph-neg MPN patients who had received Bu as therapy for Hu intolerance or failure. Of 51 patients identified, 38 (75%) achieved either complete or partial hematological response following at least one Bu cycle. Bu was generally well tolerated, with only 21/135 (15%) cycles complicated by adverse effects, predominantly cytopenia; only 6% of cycles were ceased due to treatment complications. Bu is an effective and well-tolerated agent in patients with Ph-neg MPN in the setting of Hu intolerance or unresponsiveness.

  13. Cyclical thrombocytosis, acquired von Willebrand syndrome and aggressive non-melanoma skin cancers are common in patients with Philadelphia-negative myeloproliferative neoplasms treated with hydroxyurea.

    Science.gov (United States)

    Verner, Emma; Forsyth, Cecily; Grigg, Andrew

    2014-05-01

    Abstract Cyclical thrombocytosis, acquired von Willebrand syndrome, aggressive non-melanoma skin cancers and other hydroxyurea complications have been reported in Philadelphia-negative myeloproliferative neoplasms (MPNs), but their incidence and clinical consequences have not been defined in a large cohort of patients. We conducted a retrospective analysis of 188 consecutive patients with MPNs specifically addressing the incidence of these complications. Cyclical thrombocytosis was documented in 29 patients (15%), the majority of whom were receiving hydroxyurea. Acquired von Willebrand syndrome was identified in 17 of the 84 screened patients (20%), but was not associated with any major bleeding complications. Non-melanoma skin cancers were reported in 51 patients (27%). Hydroxyurea-related fever occurred in nine of 149 patients (6%) who received hydroxyurea. Seventy-three patients (39%) experienced a total of 98 major thrombotic events, with the majority of these occurring prior to or within 3 months of the diagnosis. Cyclical thrombocytosis, acquired von Willebrand syndrome, aggressive non-melanoma skin cancers and other hydroxyurea-related complications are not infrequent in MPNs and have important clinical consequences for management.

  14. Exploring the role of gender norms in nutrition and sexual health promotion in a piloted school-based intervention: The Philadelphia Ujima™ experience.

    Science.gov (United States)

    Núñez, Ana; Robertson-James, Candace; Reels, Serita; Jeter, Janay; Rivera, Hilda; Yusuf, Zena; Liu

    2015-08-01

    Perceptions of masculinity and femininity influence behaviors and can be identified in young children and adolescents (Brannon, 2004). Thus, adolescents' engagement in health risk or promoting behaviors is influenced by perceptions of masculinity and femininity and the differences in expectations, norms and responsibilities for girls and boys (WHO, 2007). Girls and boys have different needs, and gender-based interventions that consider similarities as well as differences are needed. A gender-based nutrition and sexual health promotion program was developed and piloted by the Philadelphia Ujima Coalition in a high school setting. To explore the gender differences in adolescents' perceptions of the influence of gender norms on weight, nutrition, physical activity, and sexual health and the implication of these differences in future gender-integrated health promotion programming for youth, a content analysis of student and facilitator debriefing forms were implemented for the participating schools. The content analysis was used to identify central themes, concepts gained, and overall impact of the intervention sessions. Overall, gender norms influence healthy eating practices and activity through influencing perceptions of body type in adolescents. Gender norms also influence sexual activity and decision making through influencing perceptions of beauty, masculinity, femininity, pressures and popular concepts related to sexual activity. Thus, interventions that address gender may more effectively promote health and wellness in adolescents. Copyright © 2014 Elsevier Ltd. All rights reserved.

  15. Unexpected heterogeneity of BCR-ABL fusion mRNA detected by polymerase chain reaction in Philadelphia chromosome-positive acute lymphoblastic leukemia

    International Nuclear Information System (INIS)

    Hooberman, A.L.; Carrino, J.J.; Leibowitz, D.; Rowley, J.D.; Le Beau, M.M.; Arlin, Z.A.; Westbrook, C.A.

    1989-01-01

    The Philadelphia (Ph 1 ) chromosome results in a fusion of portions of the BCR gene from chromosome 22 and the ABL gene from chromosome 9, producing a chimeric BCR-ABL mRNA and protein. In lymphoblastic leukemias, there are two molecular subtypes of the Ph 1 chromosome, one with a rearrangement of the breakpoint cluster region (bcr) of the BCR gene, producing the same 8.5-kilobase BCR-ABL fusion mRNA seen in chronic myelogenous leukemia (CML), and the other, without a bcr rearrangement, producing a 7.0-kilobase BCR-ABL fusion mRNA that is seen only in acute lymphoblastic leukemia (ALL). The authors studied the molecular subtype of the Ph 1 chromosome in 11 cases of Ph 1 -positive ALL, including 2 with a previous diagnosis of CML, using a sensitive method to analyze the mRNA species based on the polymerase chain reaction (PCR). They observed unexpected heterogeneity in BCR-ABL mRNA in this population. They conclude that the PCR gives additional information about the Ph 1 chromosome gene products that cannot be obtained by genomic analysis, but that it cannot be used as the sole means of detection of this chromosomal abnormality in ALL because of the high incidence of false negative results

  16. Swiss electricity statistics 1996

    International Nuclear Information System (INIS)

    1997-01-01

    This detailed article discusses the following subjects: Survey of electricity supply in Switzerland in 1996; The Swiss electricity balance; Electric power generation; Electric power consumption; Generation, consumption and loads on selected days; Energy trade with other countries; Expansion capacities until 2003; Financial situation and appendix. (orig./RHM) [de

  17. Electrical installations technology

    CERN Document Server

    Whitfield, J F

    1968-01-01

    Electrical Installations Technology covers the syllabus of the City and Guilds of London Institute course No. 51, the "Electricians B Certificate”. This book is composed of 15 chapters that deal with basic electrical science and electrical installations. The introductory chapters discuss the fundamentals and basic electrical principles, including the concept of mechanics, heat, magnetic fields, electric currents, power, and energy. These chapters also explore the atomic theory of electric current and the electric circuit, conductors, and insulators. The subsequent chapter focuses on the chemis

  18. Electricity economics. Production functions with electricity

    International Nuclear Information System (INIS)

    Hu, Zhaoguang; Hu, Zheng

    2013-01-01

    The first book studies on the economics of electricity consumption. Compares the sector production functions with electricity and the commercial production functions with electricity. Introduces the global E-GDP function, the European E-GDP function and 12 national E-GDP functions. Presents the gene characters of EAI production functions and E-GDP functions for USA to see why USA's economy is entering an up-industrialization period. Discusses China's economic growth by production functions with electricity. Electricity Economics: Production Functions with Electricity studies the production output from analyzing patterns of electricity consumption. Since electricity data can be used to measure scenarios of economic performance due to its accuracy and reliability, it could therefore also be used to help scholars explore new research frontiers that directly and indirectly benefits human society. Our research initially explores a similar pattern to substitute the Cobb-Douglas function with the production function with electricity to track and forecast economic activities. The book systematically introduces the theoretical frameworks and mathematical models of economics from the perspective of electricity consumption. The E-GDP functions are presented for case studies of more than 20 developed and developing countries. These functions also demonstrate substantial similarities between human DNA and production functions with electricity in terms of four major characteristics, namely replication, mutation, uniqueness, and evolution. Furthermore, the book includes extensive data and case studies on the U.S., China, Japan, etc. It is intended for scientists, engineers, financial professionals, policy makers, consultants, and anyone else with a desire to study electricity economics as well as related applications.

  19. Electricity economics. Production functions with electricity

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Zhaoguang [State Grid Energy Research Institute, Beijing (China); Hu, Zheng [Delaware Univ., Newark, DE (United States)

    2013-07-01

    The first book studies on the economics of electricity consumption. Compares the sector production functions with electricity and the commercial production functions with electricity. Introduces the global E-GDP function, the European E-GDP function and 12 national E-GDP functions. Presents the gene characters of EAI production functions and E-GDP functions for USA to see why USA's economy is entering an up-industrialization period. Discusses China's economic growth by production functions with electricity. Electricity Economics: Production Functions with Electricity studies the production output from analyzing patterns of electricity consumption. Since electricity data can be used to measure scenarios of economic performance due to its accuracy and reliability, it could therefore also be used to help scholars explore new research frontiers that directly and indirectly benefits human society. Our research initially explores a similar pattern to substitute the Cobb-Douglas function with the production function with electricity to track and forecast economic activities. The book systematically introduces the theoretical frameworks and mathematical models of economics from the perspective of electricity consumption. The E-GDP functions are presented for case studies of more than 20 developed and developing countries. These functions also demonstrate substantial similarities between human DNA and production functions with electricity in terms of four major characteristics, namely replication, mutation, uniqueness, and evolution. Furthermore, the book includes extensive data and case studies on the U.S., China, Japan, etc. It is intended for scientists, engineers, financial professionals, policy makers, consultants, and anyone else with a desire to study electricity economics as well as related applications.

  20. Prices on electricity and transmission of electricity

    International Nuclear Information System (INIS)

    2002-01-01

    This publication contains data on prices of electric energy and transmission of electricity valid on 1 January 2002. The purpose is to illustrate the price changes on the electricity market in terms of prices for different customer categories. All companies holding network concessions for areas and all companies trading in electricity are included in this report, which is produced on an annual basis. The prices for transmission services 1 January 2002 were on the whole unchanged compared to the preceding year. For households the mean annual cost was SEK 856 for flats, SEK 4,194 one- or two-family houses with electric heating and SEK 1,881 without electric heating. (1 SEK ∼ 0.1 USD). Electricity prices rose considerably on 1 January 2002 compared to the year before. The mean price per kWh for households according to standard agreement was SEK 0.356 for deliveries to flats, SEK 0.296 for apartments in one- or two-family houses with electric heating and SEK 0.316 without electric heating. That means that the mean annual cost increased by SEK 171 for flats. For one- or two-family houses with electric heating, costs increased by SEK 1,424, and by SEK 379 for those houses without electric heating. The high costs of electricity may be explained in part by the development on the Nordic Power Exchange (Nord Pool), where the spot price increased by 75 per cent during 2001. The price development for household customers during 1996-2002 is shown in a diagram

  1. Electric circuit theory applied electricity and electronics

    CERN Document Server

    Yorke, R

    1981-01-01

    Electric Circuit Theory provides a concise coverage of the framework of electrical engineering. Comprised of six chapters, this book emphasizes the physical process of electrical engineering rather than abstract mathematics. Chapter 1 deals with files, circuits, and parameters, while Chapter 2 covers the natural and forced response of simple circuit. Chapter 3 talks about the sinusoidal steady state, and Chapter 4 discusses the circuit analysis. The fifth chapter tackles frequency response of networks, and the last chapter covers polyphase systems. This book will be of great help to electrical

  2. Electricity market 2001

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-09-01

    The electricity markets in the Nordic countries have undergone major changes since the electricity market reform work was started in the early 1990s. Sweden, Norway and Finland have had a common electricity market since 1996. The work of also reforming the Danish electricity market was begun in the year 2000. The objective of the electricity market reform is to introduce increased competition, to give the consumers greater freedom of choice and also, by open and expanded trade in electricity, create the conditions for efficient pricing. The Swedish National Energy Administration is the supervisory authority as specified in the Electricity Act, and one of the tasks entrusted to it by the Government is to follow developments on the electricity market and to regularly compile and report current market information. The purpose of the 'Electricity market 2001' publication is to meet the need for generalized and readily accessible information on the conditions on the Nordic market. Iceland is not included in the description. The publication also includes summaries of information from recent years concerning electricity generation and utilization in the Nordic countries, the structure of the electricity market from the players' perspective, trade in electricity in the Nordic countries and in Northern Europe, electricity prices in the Nordic and other countries, and the impact of the electricity sector on the environment. The publication contains data on electricity generation and use during the past years, structure of the electricity market, trade in electricity in the Nordic countries and northern Europe, electricity prices in the Nordic countries and other countries as well as impact of electricity generation system on the environment.

  3. Electricity market 2001

    International Nuclear Information System (INIS)

    2001-09-01

    The electricity markets in the Nordic countries have undergone major changes since the electricity market reform work was started in the early 1990s. Sweden, Norway and Finland have had a common electricity market since 1996. The work of also reforming the Danish electricity market was begun in the year 2000. The objective of the electricity market reform is to introduce increased competition, to give the consumers greater freedom of choice and also, by open and expanded trade in electricity, create the conditions for efficient pricing. The Swedish National Energy Administration is the supervisory authority as specified in the Electricity Act, and one of the tasks entrusted to it by the Government is to follow developments on the electricity market and to regularly compile and report current market information. The purpose of the 'Electricity market 2001' publication is to meet the need for generalized and readily accessible information on the conditions on the Nordic market. Iceland is not included in the description. The publication also includes summaries of information from recent years concerning electricity generation and utilization in the Nordic countries, the structure of the electricity market from the players' perspective, trade in electricity in the Nordic countries and in Northern Europe, electricity prices in the Nordic and other countries, and the impact of the electricity sector on the environment. The publication contains data on electricity generation and use during the past years, structure of the electricity market, trade in electricity in the Nordic countries and northern Europe, electricity prices in the Nordic countries and other countries as well as impact of electricity generation system on the environment

  4. Inspection maintenance and planning of shutdown in thermal electric generating plants

    International Nuclear Information System (INIS)

    Dezordi, W.L.; Correa, D.A.; Kina, M.

    1984-01-01

    The schedule shutdown of an industrial plant and, more specifically, of an electrical generating station, is becoming increasingly important. The major parameters to be taken into account for the planning of such a shutdown are basically of economic-financial nature such as costs of the related services (materials, equipment, manpower, etc), loss of revenue caused by the station's shutdown as well as by the station availability, and other requirements expected from it by the Load Dispatch and consumers. Improving the equipment's performances and the station's availability are the fundamental objectives to be strived for. The authors present in this paper, in an abridged form, the planning tools used for thermal electric generating plants shutdowns for inspections, maintenance and design changes implementation. (Author) [pt

  5. Electrical installation calculations advanced

    CERN Document Server

    Kitcher, Christopher

    2013-01-01

    All the essential calculations required for advanced electrical installation workThe Electrical Installation Calculations series has proved an invaluable reference for over forty years, for both apprentices and professional electrical installation engineers alike. The book provides a step-by-step guide to the successful application of electrical installation calculations required in day-to-day electrical engineering practiceA step-by-step guide to everyday calculations used on the job An essential aid to the City & Guilds certificates at Levels 2 and 3For apprentices and electrical installatio

  6. Electricity restructuring in Turkey

    International Nuclear Information System (INIS)

    Oezkyvrak, Oezlem

    2005-01-01

    Turkey implemented the electricity sector reform by which the Electricity Market Law no. 4628 passed in February 2001. Recently, all segments of the Turkish electricity sector are dominated by a vertically integrated, public-owned monopoly - Tuerkiye Elektrik Kurumu - the Turkish electricity institution. The Turkish electricity reform involves vertical deintegration of generation, transmission and distribution, introduction of competition into generation and retail sale, establishment of an independent regulatory authority and privatization of public generation and distribution entities. This article provides an overview of the Turkish electricity sector reform and defines some problems that may affect the reform success

  7. Electrical machines diagnosis

    CERN Document Server

    Trigeassou, Jean-Claude

    2013-01-01

    Monitoring and diagnosis of electrical machine faults is a scientific and economic issue which is motivated by objectives for reliability and serviceability in electrical drives.This book provides a survey of the techniques used to detect the faults occurring in electrical drives: electrical, thermal and mechanical faults of the electrical machine, faults of the static converter and faults of the energy storage unit.Diagnosis of faults occurring in electrical drives is an essential part of a global monitoring system used to improve reliability and serviceability. This diagnosis is perf

  8. Determination of time-of-travel, dispersion characteristics, and oxygen reaeration coefficients during low streamflows--Lower Tacony/Frankford Creek, Philadelphia, Pennsylvania

    Science.gov (United States)

    Senior, Lisa A.; Gyves, Matthew C.

    2010-01-01

    Time-of-travel, dispersion characteristics, and oxygen reaeration coefficients were determined by use of dye and gas tracing for a 2-mile reach of Tacony/Frankford Creek in Philadelphia, southeastern Pennsylvania. The reach frequently has concentrations of dissolved oxygen (DO) below the water-quality standard of 4 milligrams per liter during warm months. Several large combined sewer overflows (CSOs), including one of the largest in Philadelphia (former Wingohocking Creek), discharge to the study reach in this urbanized watershed, affecting water quality and the timing and magnitude of storm peaks. In addition, a dam that commonly results in backwater conditions and reduced natural reaeration is present a few hundred feet from the end of the study reach. Time-of-travel and reaeration data were collected under base-flow conditions in August and September 2009 for three sub-reaches from Roosevelt Boulevard (U.S. Route 1) to Castor Avenue. Determination of traveltimes to the centroid of the dye cloud were needed for calculation of the reaeration coefficients. Results of the dye study in Tacony/Frankford Creek indicate that traveltimes were affected by the presence of man-made structures, such as the large scour hole and pool developed at the outfall of the T14 CSO and the dam, both of which reduce stream velocities. Mean stream velocities during the dye-tracer tests ranged from a maximum of 0.44 to 0.04 foot per second through a large pool. The dispersion efficiency of the stream was determined from relations between normalized unit concentrations to time to peak for use in water-quality modeling. Oxygen reaeration coefficients determined by a constant rate-injection method using propane as the tracer gas were as low as 0.04 unit per hour in a long pool affected by backwater conditions behind a dam. The highest reaeration coefficient was 2.29 units per hour for a steep-gradient reach with multiple winding channels through gravel deposits, just downstream of a large

  9. Casebook on electric safety accidents

    International Nuclear Information System (INIS)

    1987-09-01

    This book gives concentration on electric safety accidents in domestic and abroad, which introduces general electrical safety with property of electricity, safe equipment and maintenance and protection of electric shock. It lists the cases of accident caused of electricity in domestic like accident in power substation, utilization equipment, load system and another accident by electricity like death in electric shock another by electricity like death in electric shock in new building construction, the cases caused of electricity in abroad like damage in electric shock by high voltage electric transformer, electric shock in summer and earth fault accident by fault cooling tower.

  10. Phase I Study of INNO-406, a Dual Abl/Lyn Kinase Inhibitor, in Philadelphia Chromosome-Positive Leukemias Post-Imatinib Resistance or Intolerance

    Science.gov (United States)

    Kantarjian, H.; le Coutre, P.; Cortes, J.; Pinilla-Ibarz, J.; Nagler, A.; Hochhaus, A.; Kimura, S.; Ottmann, O.

    2010-01-01

    BACKGROUND INNO-406, an oral dual Abl/Lyn tyrosine kinase inhibitor (TKI), demonstrates specific Lyn kinase activity with no or limited activity against other Src-family member kinases. Several Bcr-Abl kinase domain mutations are sensitive to INNO-406 in vitro, including the F317L and F317V mutations. In this study, we evaluated INNO-406 in Philadelphia (Ph) chromosome–positive chronic myelogenous leukemia (CML) or acute lymphocytic leukemia (ALL) post-imatinib resistance or intolerance. METHODS A dose escalation study was conducted with a starting dose of 30mg administered orally once daily. Cohorts of at least 3 patients were treated at each dose level until the maximum tolerated dose (MTD) was reached. Twice-daily (BID) dosing was also evaluated. Therapy was allowed for a maximum of 24 months. RESULTS INNO-406 was administered to 56 patients with imatinib resistance (n=40) or intolerance (n=16). Other previous treatments included nilotinib (n=20), dasatinib (n=26), and dasatinib/nilotinib (n=9). Common mutations upon study entry included Y253H (n=6), G250E (n=4), T315I (n=4) and F317L (n=3). Among 31 patients with CML in chronic phase treated with INNO-406, the major cytogenetic response rate was 19%. In this study, no responses were seen in patients with CML-AP, CML-BP, or Ph-positive ALL. Dose-limiting toxicities (DLTs) at INNO-406 480mg BID were liver function abnormalities and thrombocytopenia. CONCLUSIONS INNO-406 showed anti-CML efficacy in this heavily pretreated study population. Based on the classical determinations of both DLT and MTD, the recommended phase 2 dose of INNO-406 is 240mg orally BID. Lower doses of INNO-406 may be equally effective and should be explored. PMID:20310049

  11. Computer aided analysis of additional chromosome aberrations in Philadelphia chromosome positive acute lymphoblastic leukaemia using a simplified computer readable cytogenetic notation

    Directory of Open Access Journals (Sweden)

    Mohr Brigitte

    2003-01-01

    Full Text Available Abstract Background The analysis of complex cytogenetic databases of distinct leukaemia entities may help to detect rare recurring chromosome aberrations, minimal common regions of gains and losses, and also hot spots of genomic rearrangements. The patterns of the karyotype alterations may provide insights into the genetic pathways of disease progression. Results We developed a simplified computer readable cytogenetic notation (SCCN by which chromosome findings are normalised at a resolution of 400 bands. Lost or gained chromosomes or chromosome segments are specified in detail, and ranges of chromosome breakpoint assignments are recorded. Software modules were written to summarise the recorded chromosome changes with regard to the respective chromosome involvement. To assess the degree of karyotype alterations the ploidy levels and numbers of numerical and structural changes were recorded separately, and summarised in a complex karyotype aberration score (CKAS. The SCCN and CKAS were used to analyse the extend and the spectrum of additional chromosome aberrations in 94 patients with Philadelphia chromosome positive (Ph-positive acute lymphoblastic leukemia (ALL and secondary chromosome anomalies. Dosage changes of chromosomal material represented 92.1% of all additional events. Recurring regions of chromosome losses were identified. Structural rearrangements affecting (pericentromeric chromosome regions were recorded in 24.6% of the cases. Conclusions SCCN and CKAS provide unifying elements between karyotypes and computer processable data formats. They proved to be useful in the investigation of additional chromosome aberrations in Ph-positive ALL, and may represent a step towards full automation of the analysis of large and complex karyotype databases.

  12. Creation of a retrospective job-exposure matrix using surrogate measures of exposure for a cohort of US career firefighters from San Francisco, Chicago and Philadelphia.

    Science.gov (United States)

    Dahm, Matthew M; Bertke, Stephen; Allee, Steve; Daniels, Robert D

    2015-09-01

    To construct a cohort-specific job-exposure matrix (JEM) using surrogate metrics of exposure for a cancer study on career firefighters from the Chicago, Philadelphia and San Francisco Fire Departments. Departmental work history records, along with data on historical annual fire-runs and hours, were collected from 1950 to 2009 and coded into separate databases. These data were used to create a JEM based on standardised job titles and fire apparatus assignments using several surrogate exposure metrics to estimate firefighters' exposure to the combustion byproducts of fire. The metrics included duration of exposure (cumulative time with a standardised exposed job title and assignment), fire-runs (cumulative events of potential fire exposure) and time at fire (cumulative hours of potential fire exposure). The JEM consisted of 2298 unique job titles alongside 16,174 fire apparatus assignments from the three departments, which were collapsed into 15 standardised job titles and 15 standardised job assignments. Correlations were found between fire-runs and time at fires (Pearson coefficient=0.92), duration of exposure and time at fires (Pearson coefficient=0.85), and duration of exposure and fire-runs (Pearson coefficient=0.82). Total misclassification rates were found to be between 16-30% when using duration of employment as an exposure surrogate, which has been traditionally used in most epidemiological studies, compared with using the duration of exposure surrogate metric. The constructed JEM successfully differentiated firefighters based on gradient levels of potential exposure to the combustion byproducts of fire using multiple surrogate exposure metrics. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  13. Dimethyl sulfoxide (DMSO) waste residues and municipal waste water odor by dimethyl sulfide (DMS): the north-east WPCP plant of Philadelphia.

    Science.gov (United States)

    Glindemann, Dietmar; Novak, John; Witherspoon, Jay

    2006-01-01

    This study shows for the first time that overlooked mg/L concentrations of industrial dimethyl sulfoxide (DMSO) waste residues in sewage can cause "rotten cabbage" odor problems bydimethyl sulfide (DMS) in conventional municipal wastewater treatment. In laboratory studies, incubation of activated sludge with 1-10 mg/L DMSO in bottles produced dimethyl sulfide (DMS) at concentrations that exceeded the odor threshold by approximately 4 orders of magnitude in the headspace gas. Aeration at a rate of 6 m3 air/m3 sludge resulted in emission of the DMS into the exhaust air in a manner analogous to that of an activated sludge aeration tank. A field study atthe NEWPCP sewage treatment plant in Philadelphia found DMSO levels intermittently peaking as high as 2400 mg/L in sewage near an industrial discharger. After 3 h, the DMSO concentration in the influent to the aeration tank rose from a baseline level of less than 0.01 mg/L to a level of 5.6 mg/L and the DMS concentration in the mixed liquor rose from less than 0.01 to 0.2 mg/L. Finding this link between the intermittent occurrence of DMSO residues in influent of the treatment plant and the odorant DMS in the aeration tank was the keyto understanding and eliminating the intermittent "canned corn" or "rotten cabbage" odor emissions from the aeration tank that had randomly plagued this plant and its city neighborhood for two decades. Sewage authorities should consider having wastewater samples analyzed for DMSO and DMS to check for this possible odor problem and to determine whether DMSO emission thresholds should be established to limit odor generation at sewage treatment plants.

  14. Minimal Residual Disease at First Achievement of Complete Remission Predicts Outcome in Adult Patients with Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia.

    Directory of Open Access Journals (Sweden)

    Mingming Zhang

    Full Text Available We evaluated the prognostic effect of minimal residual disease at first achievement of complete remission (MRD at CR1 in adult patients with Philadelphia chromosome-negative acute lymphoblastic leukemia (ALL. A total of 97 patients received treatment in our center between 2007 and 2012 were retrospectively reviewed in this study. Patients were divided into two arms according to the post-remission therapy (chemotherapy alone or allogeneic hematopoietic stem cell transplantation (allo-HSCT they received. MRD was detected by four-color flow cytometry. We chose 0.02% and 0.2% as the cut-off points of MRD at CR1 for risk stratification using receiver operating characteristic analysis. The 3-year overall survival (OS and leukemia free survival (LFS rates for the whole cohort were 46.2% and 40.5%. MRD at CR1 had a significantly negative correlation with survival in both arms. Three-year OS rates in the chemotherapy arm were 70.0%, 25.2%, 0% (P = 0.003 for low, intermediate, and high levels of MRD at CR1, respectively. Three-year OS rates in the transplant arm were 81.8%, 64.3%, 27.3% (P = 0.005 for low, intermediate, and high levels of MRD at CR1, respectively. Multivariate analysis confirmed that higher level of MRD at CR1 was a significant adverse factor for OS and LFS. Compared with chemotherapy alone, allo-HSCT significantly improved LFS rates in patients with intermediate (P = 0.005 and high (P = 0.022 levels of MRD at CR1, but not patients with low level of MRD at CR1 (P = 0.851. These results suggested that MRD at CR1 could strongly predict the outcome of adult ALL. Patients with intermediate and high levels of MRD at CR1 would benefit from allo-HSCT.

  15. Green electricity buyer's guide

    International Nuclear Information System (INIS)

    Kelly, B.; Klein, S.; Olivastri, B.

    2002-06-01

    The electricity produced in whole or in large part from renewable energy sources like wind, small hydro electricity and solar energy, is generally referred to as green electricity. The authors designed this buyer's guide to assist customers in their understanding of green electricity, as the customers can now choose their electricity supplier. The considerations and steps involved in the purchasse of green electricity are identified, and advice is provided on ways to maximize the benefits from the purchase of green electricity. In Alberta and Ontario, customers have access to a competitive electricity market. The emphasis when developing this guide was placed firmly on the large buyers, as they can have enormous positive influence on the new market for green electricity. The first chapter of the document provides general information on green electricity. In chapter two, the authors explore the opportunity for environmental leadership. Chapter three reviews the basics of green electricity, which provides the link to chapter four dealing with the creation of a policy. Purchasing green electricity is dealt with in Chapter five, and maximizing the benefits of green electricity are examined in Chapter Six. 24 refs., 3 tabs

  16. Electricity market 2000

    Energy Technology Data Exchange (ETDEWEB)

    Korsfeldt, T.; Petsala, B.

    2000-08-01

    The electricity markets in the Nordic countries have undergone major changes since the electricity market reform work was started in the early 1990s. Sweden, Norway and Finland have a common electricity market since 1996.The work of also reforming the Danish electricity market was begun in the year 2000. The objective of the electricity market reform is to introduce increased competition,to give the consumers greater freedom of choice and also, by open and expanded trade in electricity, create the conditions for efficient pricing. The Swedish National Energy Administration is the supervisory authority as specified in the Electricity Act, and one of the tasks entrusted to it by the Government is to follow developments on the electricity market and to regularly compile and report current market information. The purpose of the present publication is to meet the need for generalized and readily accessible information on the conditions on the Nordic markets.The publication includes summaries of information from recent years concerning electricity generation and utilization in the Nordic countries, the structure of the electricity market from the players' perspective trade in electricity in the Nordic countries and in Northern Europe, electricity prices in the Nordic and other countries, and the impact of the electricity sector on the environment.

  17. Electrical transformer handbook

    Energy Technology Data Exchange (ETDEWEB)

    Hurst, R.W.; Horne, D. (eds.)

    2005-07-01

    This handbook is a valuable user guide intended for electrical engineering and maintenance personnel, electrical contractors and electrical engineering students. It provides current information on techniques and technologies that can help extend the life of transformers. It discusses transformer testing, monitoring, design, commissioning, retrofitting and other elements involved in keeping electrical transformers in safe and efficient operation. It demonstrates how a power transformer can be put to use and common problems faced by owners. In addition to covering control techniques, testing and maintenance procedures, this handbook covers the power transformer; control electrical power transformer; electrical power transformer; electrical theory transformer; used electrical transformer; down electrical step transformer; electrical manufacturer transformer; electrical picture transformer; electrical transformer work; electrical surplus transformer; current transformer; step down transformer; voltage transformer; step up transformer; isolation transformer; low voltage transformer; toroidal transformer; high voltage transformer; and control power transformer. The handbook includes articles from leading experts on overcurrent protection of transformers; ventilated dry-type transformers; metered load factors for low-voltage, and dry-type transformers in buildings. The maintenance of both dry-type or oil-filled transformers was discussed with reference to sealing, gaskets, oils, moisture and testing. The adoption of dynamic load practices was also discussed along with the reclamation or recycling of used lube oil, transformer dielectric fluids and aged solid insulation. A buyer's guide and directory of transformer manufacturers and suppliers was also included. refs., tabs., figs.

  18. Electricity market 2000

    International Nuclear Information System (INIS)

    Korsfeldt, T.; Petsala, B.

    2000-08-01

    The electricity markets in the Nordic countries have undergone major changes since the electricity market reform work was started in the early 1990s. Sweden, Norway and Finland have a common electricity market since 1996.The work of also reforming the Danish electricity market was begun in the year 2000. The objective of the electricity market reform is to introduce increased competition,to give the consumers greater freedom of choice and also, by open and expanded trade in electricity, create the conditions for efficient pricing. The Swedish National Energy Administration is the supervisory authority as specified in the Electricity Act, and one of the tasks entrusted to it by the Government is to follow developments on the electricity market and to regularly compile and report current market information. The purpose of the present publication is to meet the need for generalized and readily accessible information on the conditions on the Nordic markets.The publication includes summaries of information from recent years concerning electricity generation and utilization in the Nordic countries, the structure of the electricity market from the players' perspective trade in electricity in the Nordic countries and in Northern Europe, electricity prices in the Nordic and other countries, and the impact of the electricity sector on the environment

  19. Electric Holding Company Areas

    Data.gov (United States)

    Department of Homeland Security — Holding companies are electric power utilities that have a holding company structure. This vector polygon layer represents the area served by electric power holding...

  20. Driving with electrical power

    International Nuclear Information System (INIS)

    Ursin, M.; Hoeckel, M.

    2008-01-01

    This article takes a look at the chances offered to the electricity supply industry by the increasing use of battery-driven vehicles - and the advantages thus offered to the environment. The use of the vehicles' batteries to form a distributed electricity storage scheme is discussed. The authors comment that, although electrically-driven vehicles consume more power, the total primary energy consumption and pollutant emissions will be reduced. The actual electricity consumption of electric vehicles and the source of this power are examined. Power saved by the reduced use of electrical heating systems and boilers could, according to the authors, be used to charge the batteries of electric vehicles. The use of these batteries as a storage system to help regulate electricity supplies is discussed and the steps to be taken for the implementation of such a system are listed

  1. Electric Car Special

    Energy Technology Data Exchange (ETDEWEB)

    Zoethout, T.; Belin, H.; Verwijs, H.; Nicola, S.; De Saint Jacob, Y.; Gatermann, R.

    2009-09-15

    In six articles, two columns and two interviews a part of this issue is dedicated to electric car developments: about winners and losers in the electric car race; a unique business model to rolling out the electric car by the electric battery company Better Place and the automobile industry Renault Nissan; interview with entrepreneur Shai Agassi of the Indian company Better Place; the development of electric cars in Germany; interview with Jean-Jacques Chanaron, an economist specialising in innovation management and a firm believer in electric cars; start of mass production of electric vehicles at the Japanese Nissan automobile industry; the constraints in Sweden in developing fuel-efficient automobiles; plans for 1 million electric or hybrid cars by 2025 in the Netherlands.

  2. Fundamentals of electrical drives

    NARCIS (Netherlands)

    Veltman, A.; Pulle, D.W.J.; de Doncker, R.W.

    2016-01-01

    Comprehensive, user-friendly, color illustrated introductory text for electrical drive systems that simplifies the understanding of electrical machine principles Updated edition covers innovations in machine design, power semi-conductors, digital signal processors and simulation software Presents

  3. Electricity and Man (Rev.)

    Energy Technology Data Exchange (ETDEWEB)

    Asimov, Isaac

    1974-01-01

    Our whole industrial civilization depends upon cheap energy streaking out in all directions and under fingertip controls—and that would be very difficult without electric current. It would take enormous ingenuity to find substitutes. If all electricity were shut off, then all electronic devices would be dead. Electric lights would darken. Aluminum would become a rare metal. All factories would have to develop power sources on the spot and would have to switch to primitive, mechanical controls. Every house and every farm would have to give up items we have come to take for granted—not only electric lights, but electric irons, electric toasters, electric water pumps, electric control of furnaces, and so on.

  4. Electric Power Transmission Lines

    Data.gov (United States)

    Department of Homeland Security — Transmission Lines are the system of structures, wires, insulators and associated hardware that carry electric energy from one point to another in an electric power...

  5. Switzerland's electricity supply industry

    International Nuclear Information System (INIS)

    Inwyler, Ch.

    1980-01-01

    After a short description of Switzerland's electricity supply industry, the author comments on the production and consumption of electrical energy as well as on Switzerland's role within the European grid. A brief survey of electricity supply as a service is followed by a discussion of the political tools (such as e.g. the referendum, the hearing procedure etc.), which are an essential clue for understanding the position of the electricity supply industry in Switzerland. (Auth.)

  6. Electricity electron measurement

    International Nuclear Information System (INIS)

    Kim, Sang Jin; Sung, Rak Jin

    1985-11-01

    This book deals with measurement of electricity and electron. It is divided into fourteen chapters, which depicts basic of electricity measurement, unit and standard, important electron circuit for measurement, instrument of electricity, impedance measurement, power and power amount measurement, frequency and time measurement, waveform measurement, record instrument and direct viewing instrument, super high frequency measurement, digital measurement on analog-digital convert, magnetic measurement on classification by principle of measurement, measurement of electricity application with principle sensors and systematization of measurement.

  7. Mastering one's electricity purchases

    International Nuclear Information System (INIS)

    Belon, D.

    2005-01-01

    Manager of about 50000 public lighting areas, the inter-cities energy syndicate of Loire (SIEL) has started in 2003 a procedure in order to chose his electric power supplier conformably with the new rules of public electricity purchase and with the new organization of the electricity market. This article presents this approach and its experience feedback, concretized by the European call for bids launched by SIEL for the annual purchase of about 186 GWh of electric power. (J.S.)

  8. Electricity production of Slovakia

    International Nuclear Information System (INIS)

    Czodor, T.

    2003-01-01

    Here is examined the spatial structure of electric energy production divided in hydropower plants (through-flow and re-pumping), thermal power plants as the most expensive way of electric energy production and nuclear power plants where high difficulty and long-term realisation of construction projects and spent financial resources are pointed out. Work describes present structure of electric energy production and consumption and refers to alternative electric energy sources

  9. Electric glass capturing markets

    Energy Technology Data Exchange (ETDEWEB)

    Wikman, K.; Wikstroem, T.

    1996-11-01

    Electric glass has found its place on the construction market. In public buildings, electrically heatable windows are becoming the leading option for large glass walls. Studies on detached houses, both new and renovated, show that floor heating combined with electrically heatable windowpanes is the best choice with respect to resident`s comfort. (orig.)

  10. Electric dipole moments reconsidered

    International Nuclear Information System (INIS)

    Rupertsberger, H.

    1989-01-01

    The electric dipole moments of elementary particles, atoms, molecules and their connection to the electric susceptibility are discussed for stationary states. Assuming rotational invariance it is emphasized that for such states only in the case of a parity and time reversal violating interaction the considered particles can obtain a nonvanishing expectation value for the electric dipole moment. 1 fig., 13 refs. (Author)

  11. Electric and hybrid vehicles

    Science.gov (United States)

    1979-01-01

    Report characterizes state-of-the-art electric and hybrid (combined electric and heat engine) vehicles. Performance data for representative number of these vehicles were obtained from track and dynamometer tests. User experience information was obtained from fleet operators and individual owners of electric vehicles. Data on performance and physical characteristics of large number of vehicles were obtained from manufacturers and available literature.

  12. Future Electricity Markets

    DEFF Research Database (Denmark)

    Pinson, Pierre

    2015-01-01

    The changing face of energy production in Europe necessitates a rethink in the way that electricity markets are structured. The ‘5s’ (Future Electricity Markets) project is a multi-disciplinary project that is looking to challenge the current approach to the design and operation of electricity...

  13. Schneider Electric sozdajot set

    Index Scriptorium Estoniae

    2003-01-01

    Maailma juhtiv elektriseadmete müüja Schneider Electric ühendab oma ettevõtted Balti- ja Põhjamaades uude divisjoni, mille nimeks saab Schneider Nordic Baltic. Eestis luuakse AS Schneider Electric Eesti, mis seni tegutses AS-i Lexel Electric nime all

  14. Electric Vehicle Technician

    Science.gov (United States)

    Moore, Pam

    2011-01-01

    With President Obama's goal to have one million electric vehicles (EV) on the road by 2015, the electric vehicle technician should have a promising and busy future. "The job force in the car industry is ramping up for a revitalized green car industry," according to Greencareersguide.com. An electric vehicle technician will safely troubleshoot and…

  15. Electric Current Solves Mazes

    Science.gov (United States)

    Ayrinhac, Simon

    2014-01-01

    We present in this work a demonstration of the maze-solving problem with electricity. Electric current flowing in a maze as a printed circuit produces Joule heating and the right way is instantaneously revealed with infrared thermal imaging. The basic properties of electric current can be discussed in this context, with this challenging question:…

  16. Fundamentals of electrical drives

    CERN Document Server

    Veltman, André; De Doncker, Rik W

    2007-01-01

    Provides a comprehensive introduction to various aspects of electrical drive systems. This volume provides a presentation of dynamic generic models that cover all major electrical machine types and modulation/control components of a drive as well as dynamic and steady state analysis of transformers and electrical machines.

  17. Electricity in South Africa

    International Nuclear Information System (INIS)

    Davis, Mark; Steyn, Grove

    1998-09-01

    Contains Executive Summary and Chapters on: Introductory background; The South African energy sector; The development and regulation of the South African electricity supply industry; Electricity supply and demand; Eskom: South Africa's public utility; Electricity distribution; Household electrification; Regional integration and environmental issues; Regulation and emerging policies - pointers to the future. (Author)

  18. The electricity market 2003

    International Nuclear Information System (INIS)

    2003-01-01

    The electricity markets in the Nordic countries have undergone major changes since the electricity market reform work was started in the early 1990s. We now have a common Nordic electricity market that includes all of the Nordic countries, with the exception of Iceland. The objective of the electricity market reform is to introduce increased competition, to give consumers greater freedom of choice and also, by open and increased trade in electricity, create the conditions for efficient pricing. The Swedish Energy Agency is the supervisory authority specified in the Electricity Act, and one of the tasks entrusted to it by the Government is to follow developments on the electricity market and regularly compile and report current market information. The purpose of 'The Electricity Market 2003' publication is to meet the need for generalized and easily accessible information on the conditions on the Nordic market. The publication also includes summaries of the information from recent years concerning power generation and utilization in the Nordic countries, the structure of the electricity market from the players' perspective, trade in electricity in the Nordic countries and in northern Europe, electricity prices in the Nordic and other countries, and the impact of the electricity sector on the environment

  19. Predictive value of minimal residual disease in Philadelphia-chromosome-positive acute lymphoblastic leukemia treated with imatinib in the European intergroup study of post-induction treatment of Philadelphia-chromosome-positive acute lymphoblastic leukemia, based on immunoglobulin/T-cell receptor and BCR/ABL1 methodologies

    Science.gov (United States)

    Cazzaniga, Giovanni; De Lorenzo, Paola; Alten, Julia; Röttgers, Silja; Hancock, Jeremy; Saha, Vaskar; Castor, Anders; Madsen, Hans O.; Gandemer, Virginie; Cavé, Hélène; Leoni, Veronica; Köhler, Rolf; Ferrari, Giulia M.; Bleckmann, Kirsten; Pieters, Rob; van der Velden, Vincent; Stary, Jan; Zuna, Jan; Escherich, Gabriele; zur Stadt, Udo; Aricò, Maurizio; Conter, Valentino; Schrappe, Martin; Valsecchi, Maria Grazia; Biondi, Andrea

    2018-01-01

    The prognostic value of minimal residual disease (MRD) in Philadelphia-chromosome-positive (Ph+) childhood acute lymphoblastic leukemia (ALL) treated with tyrosine kinase inhibitors is not fully established. We detected MRD by real-time quantitative polymerase chain reaction (RQ-PCR) of rearranged immunoglobulin/T-cell receptor genes (IG/TR) and/or BCR/ABL1 fusion transcript to investigate its predictive value in patients receiving Berlin-Frankfurt-Münster (BFM) high-risk (HR) therapy and post-induction intermittent imatinib (the European intergroup study of post-induction treatment of Philadelphia-chromosome-positive acute lymphoblastic leukemia (EsPhALL) study). MRD was monitored after induction (time point (TP)1), consolidation Phase IB (TP2), HR Blocks, reinductions, and at the end of therapy. MRD negativity progressively increased over time, both by IG/TR and BCR/ABL1. Of 90 patients with IG/TR MRD at TP1, nine were negative and none relapsed, while 11 with MRD<5×10−4 and 70 with MRD≥5×10−4 had a comparable 5-year cumulative incidence of relapse of 36.4 (15.4) and 35.2 (5.9), respectively. Patients who achieved MRD negativity at TP2 had a low relapse risk (5-yr cumulative incidence of relapse (CIR)=14.3[9.8]), whereas those who attained MRD negativity at a later date showed higher CIR, comparable to patients with positive MRD at any level. BCR/ABL1 MRD negative patients at TP1 had a relapse risk similar to those who were IG/TR MRD negative (1/8 relapses). The overall concordance between the two methods is 69%, with significantly higher positivity by BCR/ABL1. In conclusion, MRD monitoring by both methods may be functional not only for measuring response but also for guiding biological studies aimed at investigating causes for discrepancies, although from our data IG/TR MRD monitoring appears to be more reliable. Early MRD negativity is highly predictive of favorable outcome. The earlier MRD negativity is achieved, the better the prognosis. PMID

  20. Electricity demand in Tunisia

    International Nuclear Information System (INIS)

    Gam, Imen; Ben Rejeb, Jaleleddine

    2012-01-01

    This paper examines the global electricity demand in Tunisia as a function of gross domestic product in constant price, the degree of urbanization, the average annual temperature, and the real electricity price per Kwh. This demand will be examined employing annual data over a period spanning almost thirty one years from 1976 to 2006. A long run relationship between the variables under consideration is determined using the Vector Autoregressive Regression. The empirical results suggest that the electricity demand in Tunisia is sensitive to its past value, any changes in gross domestic product and electricity price. The electricity price effects have a negative impact on long-run electricity consumption. However, the gross domestic product and the past value of electricity consumption have a positive effect. Moreover, the causality test reveals a unidirectional relationship between price and electricity consumption. Our empirical findings are effective to policy makers to maintain the electricity consumption in Tunisia by using the appropriate strategy. - Highlights: ► This paper examined the electricity demand in Tunisia in the long-run. ► The empirical analysis revealed that in the long-run the electricity demand is affected by changes in its past value, GDP in constant price and real electricity price. ► There is a unidirectional relationship between price and electricity consumption, that is to say, that the electricity price causes the consumption. ► Those results suggest that a pricing policy can be an effective instrument to rationalize the electricity consumption in Tunisia in the long-run.

  1. Electricity sequence control

    International Nuclear Information System (INIS)

    Shin, Heung Ryeol

    2010-03-01

    The contents of the book are introduction of control system, like classification and control signal, introduction of electricity power switch, such as push-button and detection switch sensor for induction type and capacitance type machinery for control, solenoid valve, expression of sequence and type of electricity circuit about using diagram, time chart, marking and term, logic circuit like Yes, No, and, or and equivalence logic, basic electricity circuit, electricity sequence control, added condition, special program control about choice and jump of program, motor control, extra circuit on repeat circuit, pause circuit in a conveyer, safety regulations and rule about classification of electricity disaster and protective device for insulation.

  2. Electrical installation calculations basic

    CERN Document Server

    Kitcher, Christopher

    2013-01-01

    All the essential calculations required for basic electrical installation workThe Electrical Installation Calculations series has proved an invaluable reference for over forty years, for both apprentices and professional electrical installation engineers alike. The book provides a step-by-step guide to the successful application of electrical installation calculations required in day-to-day electrical engineering practice. A step-by-step guide to everyday calculations used on the job An essential aid to the City & Guilds certificates at Levels 2 and 3Fo

  3. Managing electrical safety

    CERN Document Server

    Wiggins, James H, Jr

    2001-01-01

    Managing Electrical Safety provides an overview of electric basics, hazards, and established standards that enables you to understand the hazards you are likely to encounter in your workplace. Focusing on typical industrial environments-which utilize voltages much higher than household or office circuits-the author identifies the eight key components of an electrical safety program and examines each using a model safety management process. You'll learn how to identify electrical hazards, how to prescribe necessary electrical Personal Protective Equipment, how to ensure that equipment is de-ene

  4. Electric wiring domestic

    CERN Document Server

    Coker, A J

    1992-01-01

    Electric Wiring: Domestic, Tenth Edition, is a clear and reliable guide to the practical aspects of domestic electric wiring. Intended for electrical contractors, installation engineers, wiremen and students, its aim is to provide essential up to date information on modern methods and materials in a simple, clear, and concise manner. The main changes in this edition are those necessary to bring the work into line with the 16th Edition of the Regulations for Electrical Installations issued by the Institution of Electrical Engineers. The book begins by introducing the basic features of domestic

  5. Pragmatic electrical engineering fundamentals

    CERN Document Server

    Eccles, William

    2011-01-01

    Pragmatic Electrical Engineering: Fundamentals introduces the fundamentals of the energy-delivery part of electrical systems. It begins with a study of basic electrical circuits and then focuses on electrical power. Three-phase power systems, transformers, induction motors, and magnetics are the major topics.All of the material in the text is illustrated with completely-worked examples to guide the student to a better understanding of the topics. This short lecture book will be of use at any level of engineering, not just electrical. Its goal is to provide the practicing engineer with a practi

  6. Electric Vehicle Interaction at the Electrical Circuit Level

    Science.gov (United States)

    2018-01-01

    The objective of the Electric Vehicle Interaction at the Electrical Circuit Level project was to investigate electric vehicle (EV) charging as a means of mitigating transient over-voltages (TOVs) on the circuit level electric utility distribution gri...

  7. Electric power production contra electricity savings

    International Nuclear Information System (INIS)

    Schleisner, L.; Grohnheit, P.E.; Soerensen, H.

    1991-01-01

    The expansion of electricity-producing plants has, in Denmark until now, taken place in accordance with the demand for electricity. Recently, it has been suggested that the cost of the further development of such systems is greater than the cost of instigating and carrying out energy conservation efforts. The aim of the project was to evaluate the consequences for power producing plants of a reduction of the electricity consumption of end-users. A method for the analysis of the costs involved in the system and operation of power plants contra the costs that are involved in saving electricity is presented. In developing a model of this kind, consideration is given to the interplay of the individual saving project and the existing or future electricity supply. Thus it can be evaluated to what extent it would be advisable to substitute investments in the development of the capacity of the power plants with investments in the reduction of electricity consumption by the end users. This model is described in considerable detail. It will be tested in representative situations and locations throughout the Nordic countries. (AB) 17 refs

  8. Electric power annual, 1990

    International Nuclear Information System (INIS)

    1992-01-01

    The Electric Power Annual presents a summary of electric utility statistics at the national, regional and State levels. The objective of the publication is to provide industry decisionmakers, government policy-makers, analysts and the general public with historical data that may be used in understanding US electricity markets. ''The Industry at a Glance'' section presents a profile of the electric power industry ownership and performance; a review of key statistics for the year; and projections for various aspects of the electric power industry through 2010. Subsequent sections present data on generating capability, including proposed capability additions; net generation; fossil-fuel statistics; electricity sales, revenue, and average revenue per kilowatthour sold; financial statistics; environmental statistics; and electric power transactions. In addition, appendices provide supplemental data on major disturbances and unusual occurrences. Each section contains related text and tables and refers the reader to the appropriate publication that contains more detailed data on the subject matter

  9. Electricity in Europe

    International Nuclear Information System (INIS)

    Holmes, A.

    1985-01-01

    European electricity consumption and demand is summarized in Chapter 1. The relationship between government and electricity producers is touched on. Five further chapters examine aspects of electricity in Europe. Chapter 2 discusses the electricity trade (import and export of electricity). The next looks at the current status of nuclear power in individual European countries. The environmental impact of generating electricity (eg acid rain, radioactive waste disposal) is assessed next and then the price of electricity in Europe is reviewed (with comparisons between the countries). Profiles of the situation in each country are presented in the last chapter. There are 72 tables presenting the facts and figures on which the text is based. (U.K.)

  10. The Electric Vehicle Development

    DEFF Research Database (Denmark)

    Wang, Jingyu; Liu, Yingqi; Kokko, Ari

    2014-01-01

    In order to respond to the energy crisis and environment problem, countries carry out their research and promotion about electric vehicles. As the ten cities one thousand new energy buses started in 2009, the new energy vehicles have been greatly developed in China, while the development...... in three aspects-city environment, government and stakeholders. Then the paper discusses the promotion ways and role of government and consumer. Finally, the paper offers some suggestions to promote electric vehicles in China: focusing on feasibility and adaptability of electric vehicles, playing...... of electric vehicles is not that good. This paper selects four cities-Los Angeles, Kanagawa, Hamburg, Amsterdam-that promote electric vehicles successfully and deeply analyzes the development of electric vehicles in these four cities and analyzes the factors that affect the development of electric vehicles...

  11. Pervasive Electricity Distribution System

    Directory of Open Access Journals (Sweden)

    Muhammad Usman Tahir

    2017-06-01

    Full Text Available Now a days a country cannot become economically strong until and unless it has enough electrical power to fulfil industrial and domestic needs. Electrical power being the pillar of any country’s economy, needs to be used in an efficient way. The same step is taken here by proposing a new system for energy distribution from substation to consumer houses, also it monitors the consumer consumption and record data. Unlike traditional manual Electrical systems, pervasive electricity distribution system (PEDS introduces a fresh perspective to monitor the feeder line status at distribution and consumer level. In this system an effort is taken to address the issues of electricity theft, manual billing, online monitoring of electrical distribution system and automatic control of electrical distribution points. The project is designed using microcontroller and different sensors, its GUI is designed in Labview software.

  12. Diagnosis, prevention, and management of bleeding episodes in Philadelphia-negative myeloproliferative neoplasms: recommendations by the Hemostasis Working Party of the German Society of Hematology and Medical Oncology (DGHO) and the Society of Thrombosis and Hemostasis Research (GTH).

    Science.gov (United States)

    Appelmann, Iris; Kreher, Stephan; Parmentier, Stefani; Wolf, Hans-Heinrich; Bisping, Guido; Kirschner, Martin; Bergmann, Frauke; Schilling, Kristina; Brümmendorf, Tim H; Petrides, Petro E; Tiede, Andreas; Matzdorff, Axel; Griesshammer, Martin; Riess, Hanno; Koschmieder, Steffen

    2016-04-01

    Philadelphia-negative myeloproliferative neoplasms (Ph-negative MPN) comprise a heterogeneous group of chronic hematologic malignancies. The quality of life, morbidity, and mortality of patients with MPN are primarily affected by disease-related symptoms, thromboembolic and hemorrhagic complications, and progression to myelofibrosis and acute leukemia. Major bleeding represents a common and important complication in MPN, and the incidence of such bleeding events will become even more relevant in the future due to the increasing disease prevalence and survival of MPN patients. This review discusses the causes, differential diagnoses, prevention, and management of bleeding episodes in patients with MPN, aiming at defining updated standards of care in these often challenging situations.

  13. Panel presentation: Impact of combination gas/electric companies on the use of natural gas

    International Nuclear Information System (INIS)

    Stalon, C.G.

    1992-01-01

    This paper looks at the advantages and disadvantages of combined gas and electric utilities. It uses a priori reasoning and empirical analysis to present a case that combined utilities actually have the power to do more good for the service area than two separate utilities striving to compete. Unfortunately, the monopoly status of a combined utility may seize the opportunity to maintain the status quo and stop innovation. Based on some simple research, the author found that most combination utilities' electric divisions had higher prices than comparable straight electric utilities, (2) most combination utilities' electric division had higher unit costs than comparable straight electric utilities, and (3) there was no statistical significant difference in price or unit costs between the gas divisions of combination utilities and straight gas utilities. The paper ends with a discussion of policy options and subsequent consequences of preserving the status quo, forced separation of all such combinations, and the review on a case-by-case basis of each combination utility

  14. Phase 1 study of INNO-406, a dual Abl/Lyn kinase inhibitor, in Philadelphia chromosome-positive leukemias after imatinib resistance or intolerance.

    Science.gov (United States)

    Kantarjian, Hagop; le Coutre, Phillipp; Cortes, Jorge; Pinilla-Ibarz, Javier; Nagler, Arnon; Hochhaus, Andreas; Kimura, Shinya; Ottmann, Oliver

    2010-06-01

    : INNO-406, a dual v-abl Abelson murine leukemia viral oncogene homolog (Abl)/v-yes-1 Yamaguchi sarcoma viral-related oncogene homolog (Lyn) tyrosine kinase inhibitor (TKI), has demonstrated specific Lyn kinase inhibitory activity with no or limited activity against other sarcoma (Src) family member kinases. Several breakpoint cluster region (Bcr)-Abl kinase domain mutations are sensitive to INNO-406 in vitro, including mutations that involve a phenylalanine-to-leucine or phenylalanine-to-valine substitution at codon 317 (F317L and F317V, respectively). In the current study, the authors evaluated the use of INNO-406 in patients with Philadelphia (Ph) chromosome-positive chronic myelogenous leukemia (CML) or acute lymphocytic leukemia (ALL) after imatinib resistance or intolerance. : A dose-escalation study was conducted at a starting dose of oral INNO-406 30 mg once daily. Cohorts of at least 3 patients were treated at each dose level until the maximum tolerated dose (MTD) was reached. Twice-daily dosing also was evaluated. Therapy was allowed to continue for a maximum of 24 months. : INNO-406 was administered to 56 patients with imatinib resistance (n = 40) or intolerance (n = 16). Other previous treatments included nilotinib (n = 20 patients), dasatinib (n = 26 patients), and dasatinib/nilotinib (n = 9 patients). Common mutations at the time of study entry included a tyrosine-to-histidine substitution at codon 253 (Y253H) (n = 6 patients), a glycine-to-glutamic acid substitution at codon 250 (G250E) (n = 4 patients), a threonine-to-isoleucine substitution at codon 315 (T315I) (n = 4 patients), and F317L (n = 3 patients). Of 31 patients with CML in chronic phase who received INNO-406, the major cytogenetic response rate was 19%. No responses were observed in patients who had CML in accelerated phase, CML in blastic phase, or Ph-positive ALL. The dose-limiting toxicities (DLTs) at an INNO-406 dose of 480 mg twice daily were liver function abnormalities and

  15. Classroom implementation of the practices learned in the Master of Chemistry Education program by the School District of Philadelphia's high school chemistry teachers

    Science.gov (United States)

    Jayaraman, Uma Devi

    This dissertation reports the results of an exploratory case study utilizing quantitative and qualitative methodologies intended to ascertain the extent and differences of implementation of research-based instructional practices, learned in an intensive 26-month professional development, in their urban classrooms. Both the extent and differences in the implementation of practices were investigated in relation to the lesson design and implementation, content, and classroom culture aspects of research-based practices. Additionally, this research includes the concerns of the teachers regarding the factors that helped or hindered the implementation of research-based practices in their classrooms. Six graduates of the Master of Chemistry Education Program who were teaching a chemistry course in a high school in the School District of Philadelphia at the time of the study (2006-8), were the case. The teachers completed a concerns questionnaire with closed and open-ended items, and rated their perceptions of the extent of implementation of the practices in their urban classrooms. Additionally, the teachers were observed and rated by the researcher using a reform-teaching observation protocol and were interviewed individually. Also, the teachers submitted their lesson plans for the days they were observed. Data from these sources were analyzed to arrive at the findings for this study. The research findings suggest that the group of teachers in the study implemented the research-based practices in their classrooms to a low extent when compared to the recommended practices inherent to the MCE Program. The extents of implementation of the practices differed widely among the teachers, from being absent to being implemented at a high level, with inconsistent levels of implementation from various data sources. Further, the teachers expressed the depth of knowledge (gained in the MCE Program), formal laboratory exercises and reports, administrative support, self

  16. [Clinical significance of JAK2、CALR and MPL gene mutations in 1 648 Philadelphia chromosome negative myeloproliferative neoplasms patients from a single center].

    Science.gov (United States)

    Li, M Y; Chao, H Y; Sun, A N; Qiu, H Y; Jin, Z M; Tang, X W; Han, Y; Fu, C C; Chen, S N; Wu, D P

    2017-04-14

    Objective: To explore the prevalences of JAK2, CALR and MPL gene mutations and the mutation types in patients with Philadelphia chromosome negative myeloproliferative neoplasms (MPNs) , and to compare their clinical characteristics of different mutation types with each other and mutation negative group. Methods: The mutations of JAK2 V617F, JAK2 gene at exon 12, CALR gene at exon 9 and MPL gene at exon 10 in 1 648 Ph negative MPNs patients were detected by direct sequencing. Results: ① The JAK2V617F mutation was found in 471 (92.7%) of 508 PV patients, 819 (78.1%) of 1 049 ET patients and 74 (81.3%) of 91 PMF patients respectively, with the total mutation rate as 82.8% (1 364/1 648) . The JAK2 exon12 mutation was found in 9 (1.7%) of 508 PV patients, none was found in ET or PMF patients, with the total mutation rate as 0.5% (9/1 648) . The CALR mutation was found in 132 (12.6%) of 1 049 ET patients and 11 (12.1%) of 91 PMF patients respectively, with the total mutation rate as 8.7% (143/1 648) ; the MPL mutation was found in 9 (0.9%) of 1 049 ET patients and 1 (1.1%) of 91 PMF patients respectively, with the total mutation rate as 0.6% (10/1 648) . The co-occurrence of any two types of driver gene mutations was not detected by direct sequencing. ②The median onset age of patients with JAK2V617F[61 (15-95) y] was significant higher than of with JAK2 exon12 mutation[49 (33-62) y] or without mutations[42 (3-78) y] ( P MPL mutation[59 (22-71) y] ( P >0.05) . Patients with JAK2V617F had higher white blood cell count and hemoglobin level ( P MPL mutation ( P =0.013) . The platelet count of patients with CALR mutation was significantly higher than of with JAK2V617F[966 (400-2 069) ×10(9)/L vs 800 (198-3 730) ×10(9)/L, P MPL gene mutation revealed normal karyotype. Conclusions: Driver gene mutations detection could ensure the diagnosis and prognosis judgment of MPN more reliable, different subtypes of MPNs had different profiles of driver gene mutations, the latter

  17. A study of the attitudes and academic achievement in biology of females in a single-sex school vs. a coeducational school in the Philadelphia Archdiocesan secondary schools

    Science.gov (United States)

    Proach, John Ann

    2000-11-01

    There is proof that the educational system has conveyed unrealistic role expectations and has neglected to address the changing needs of girls. Children form attitudes about themselves and others based on the communications they get over time from parents, other adults, peers, and a variety of societal influences, including school. This study focused on two groups of tenth-grade high school, female, biology students in the Archdiocese of Philadelphia. The purpose was to compare attitude in science and academic achievement of females in a single-sex vs. a coeducational school. Data collection included three attitudinal surveys: Women in Science, Science Attitude Scale, and Perceptions of Science and Scientists, also the National Association of Biology Teachers/National Science Teachers High School Biology Examination Version B. administered as a pretest and posttest to measure academic achievement. These instruments were used to determine if the differences between attitudes and perceptions toward science and achievement in science were alike for females in a single-sex school and a coeducational school. The study also tested to see if females in a single-sex school would attain greater academic achievement in biology than girls in a coeducational school. The Chi-square statistic was used to analyze data in the three attitudinal surveys. The NABT/NSTA High School Biology Examination determined the students' initial and final competency levels in general biology. The mean science achievement of each of the two groups was tested for statistical significance using the t-test. In the two schools the t-test statistic showed significant difference between the pretest and a slight statistical difference on the posttest; the preferred analysis was an ANCOVA used to compare the posttest scores using the pretest as a covariate. The data implies that attitudes and perceptions are basically the same in both environments with minor differences. Results of these analyses suggest

  18. Demand for electrical energy

    International Nuclear Information System (INIS)

    Bergougnoux, J.; Fouquet, D.

    1983-01-01

    The different utilizations of electric energy are reviewed in the residential and tertiary sectors, in the industry. The competitive position of electricity in regard to other fuels has been strengthned by the sudden rise in the price of oil in 1973-1974 and 1979-1980. The evolution of electricity prices depended on the steps taken to adjust the electricity generation system. The substitution of electricity applications for hydro-carbons is an essential point of energy policy. The adjustment at all times, at least cost and most reliability, of the supply of electricity to the demand for it is a major problem in the design and operation of electric systems. National demand for power at a given moment is extremely diversified. Electricity consumption presents daily and seasonal variations, and variations according to the different sectors. Forecasting power requirements is for any decision on operation or investment relating to an electrical system. Load management is desirable (prices according to the customers, optional tariffs for ''peak-day withdrawal''). To conclude, prospects for increased electricity consumption are discussed [fr

  19. Essays on electricity markets

    Energy Technology Data Exchange (ETDEWEB)

    Rud, Linda

    2009-07-01

    The report covers several topics of electricity markets: The first essay, 'Selected Topics on Early Electricity Market Design in Norway' studies market design issues in establishing the market-based Norwegian electricity market. Essays 2-4 focus on issues of network congestion: 'Capacity Charges: A Price Adjustment Process for Managing Congestion in Electricity Transmission Networks' presents the capacity charge approach for managing transmission constraints in electricity networks. 'Understanding the Stochastics of Nodal Prices: Price Processes in a Constrained Network' seeks a further understanding of stochastic nodal prices processes. 'Investment Evaluation in a Constrained Electricity Network with Stochastic Nodal Price Processes' studies how the interaction of the competitive market and the capacitated network affects the evaluation of investments under uncertainty, and points out potential pitfalls of evaluation. In the last essay, 'A Newsboy Model Perspective on the Power Market: The Case of a Wind Power Producer' we discuss aspects of optimal bidding for a wind power producer. (Author)

  20. Electrical system architecture

    Science.gov (United States)

    Algrain, Marcelo C [Peoria, IL; Johnson, Kris W [Washington, IL; Akasam, Sivaprasad [Peoria, IL; Hoff, Brian D [East Peoria, IL

    2008-07-15

    An electrical system for a vehicle includes a first power source generating a first voltage level, the first power source being in electrical communication with a first bus. A second power source generates a second voltage level greater than the first voltage level, the second power source being in electrical communication with a second bus. A starter generator may be configured to provide power to at least one of the first bus and the second bus, and at least one additional power source may be configured to provide power to at least one of the first bus and the second bus. The electrical system also includes at least one power consumer in electrical communication with the first bus and at least one power consumer in electrical communication with the second bus.

  1. Electric power monthly

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-08-01

    The Energy Information Administration (EIA) prepares the Electric Power Monthly (EPM) for a wide audience including Congress, Federal and State agencies, the electric utility industry, and the general public. This publication provides monthly statistics for net generation, fossil fuel consumption and stocks, quantity and quality of fossil fuels, cost of fossil fuels, electricity sales, revenue, and average revenue per kilowatthour of electricity sold. Data on net generation, fuel consumption, fuel stocks, quantity and cost of fossil fuels are also displayed for the North American Electric Reliability Council (NERC) regions. The EIA publishes statistics in the EPM on net generation by energy source, consumption, stocks, quantity, quality, and cost of fossil fuels; and capability of new generating units by company and plant. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead.

  2. Control of Electric Vehicle

    OpenAIRE

    Huang, Qi; Chen, Yong; Li, Jian

    2010-01-01

    In this chapter, the modeling of electric vehicle is discussed in detail. Then, the control of electric vehicle driven by different motors is discussed. Both brushed and brushless DC (Direct Current) motors are discussed. And for AC (Alternative Current) motors, the discussion is focused on induction motor and permanent magnet synchronous motor. The design of controllers for different motor-driven electric vehicle is discussed in-depth, and the tested high-performance control strategies for d...

  3. The earth's electrical environment

    International Nuclear Information System (INIS)

    Anon.

    1986-01-01

    This latest addition to the Studies in Geophysics series explores in scientific detail the phenomenon of lighting, cloud and thunderstorm electricity, and global and regional electrical processes. Consisting of 16 papers by outstanding experts in a number of fields, this volume compiles and reviews many recent advances in such research areas as meteorology, chemistry, electrical engineering, and physics and projects how new knowledge could be applied to benefit mankind

  4. Principles of electrical safety

    CERN Document Server

    Sutherland, Peter E

    2015-01-01

    Principles of Electrical Safety discusses current issues in electrical safety, which are accompanied by series' of practical applications that can be used by practicing professionals, graduate students, and researchers. .  Provides extensive introductions to important topics in electrical safety Comprehensive overview of inductance, resistance, and capacitance as applied to the human body Serves as a preparatory guide for today's practicing engineers

  5. Operational electricity transmission rates

    International Nuclear Information System (INIS)

    Roggen, M.

    1997-01-01

    In a liberalized electricity market both the consumers and the producers of electricity must pay for the use of the power transmission network. Thus, the net manager has unlimited options to realize efficiency improvements. A neutral and transparent management of the power grid is necessary to avoid disturbance of the market. KEMA Consulting translated abstract ideas and strategic advices to operational concepts in its report 'A framework for the determination of tariffs of the transport in the Dutch electricity sector'

  6. Perspectives of electricity supply

    International Nuclear Information System (INIS)

    1988-01-01

    The 7 papers read at the symposium discussed the following subjects: Effects of the CO 2 problems of fossil energy systems on the world climate; status and perspectives of the German electricity industry in terms of competitiveness; The European electricity market and the integrated power supply system; Power supply without nuclear power; Costs and rates for households and other customers; Renewable energy sources and their contribution to energy supply in the Federal Republic of Germany; Electricity utilities as service partners. (UA) [de

  7. Competition in electricity markets

    International Nuclear Information System (INIS)

    Taylor, W.

    1996-01-01

    This article examines expanded wholesale and retail competition and the effect that they are likely to have on the electric power industry. The author believes that expanded wholesale competition is good and will bring immediate benefit to all electric consumers; however, based on the experience of the natural gas industry and the electric power industry in California and other parts of the world, the author counsels caution in moving toward expanded retail competition

  8. Electrical control of superparamagnetism

    Science.gov (United States)

    Yamada, Kihiro T.; Koyama, Tomohiro; Kakizakai, Haruka; Miwa, Kazumoto; Ando, Fuyuki; Ishibashi, Mio; Kim, Kab-Jin; Moriyama, Takahiro; Ono, Shimpei; Chiba, Daichi; Ono, Teruo

    2017-01-01

    The electric field control of superparamagnetism is realized using a Cu/Ni system, in which the deposited Ni shows superparamagnetic behavior above the blocking temperature. An electric double-layer capacitor (EDLC) with the Cu/Ni electrode and a nonmagnetic counter electrode is fabricated to examine the electric field effect on magnetism in the magnetic electrode. By changing the voltage applied to the EDLC, the blocking temperature of the system is clearly modulated.

  9. Electrical and electronic principles

    CERN Document Server

    Knight, S A

    1991-01-01

    Electrical and Electronic Principles, 2, Second Edition covers the syllabus requirements of BTEC Unit U86/329, including the principles of control systems and elements of data transmission. The book first tackles series and parallel circuits, electrical networks, and capacitors and capacitance. Discussions focus on flux density, electric force, permittivity, Kirchhoff's laws, superposition theorem, arrangement of resistors, internal resistance, and powers in a circuit. The text then takes a look at capacitors in circuit, magnetism and magnetization, electromagnetic induction, and alternating v

  10. Essays on electricity theft

    Science.gov (United States)

    Steadman, Keva Ullanda

    Electricity theft is a relatively unknown crime with high economic costs. In this dissertation, I try to identify the factors that motivate persons to steal electricity. First, I use a panel dataset of 97 countries spanning the five year period 2003--2007 to estimate a model that describes the effect of the unemployment rate, GDP per capita, male population and urbanization on theft, robbery and homicide rates. The results are consistent with previous empirical work on crime and economic opportunity. The second and main contribution of this paper is to estimate the same model using distribution loss as a proxy for electricity theft. The results show that the unemployment rate, a key explanatory economic factor for crime, cannot explain variation in electricity theft, although there is some evidence, albeit weak, supporting correlation in rich countries. Therefore, policies that target the reduction of property crime through a reduction in unemployment will have no effect on electricity theft. The third contribution relates to the role that political institutions play in the incentives to steal electricity. After control for socioeconomic factors, I find that there is no relationship between political governance indicators and electricity theft. In the second and third chapters, I compare the United States, a high income, low electricity theft country with Jamaica, a middle income, high electricity theft country. The effect of unemployment on electricity theft mirrors the results found in the first chapter. In the United States, electricity theft is affected by changes in economic conditions but in Jamaica, it is not. These results suggest that the state of institutions plays a role in how social norms are determined. Poor countries will be more likely than rich countries to have weak institutions with social norms that encourage electricity theft.

  11. Electricity in France

    International Nuclear Information System (INIS)

    Audigier, Pierre

    1999-12-01

    Contains Executive Summary and Chapters on: Historical background; The Nationalisation Law of 1946 and the present electricity regulatory framework; Other regulations and policies having an impact on the French electricity system; Forces for and against Liberalisation; The legislative framework in preparation; Electricity costs and prices; The main industrial player. EdF; Key nuclear issues; EdF and the HV transmission network; The non-nationalised distributors; Other players on the generation side; Conclusions. (Author)

  12. Electricity of machine tool

    International Nuclear Information System (INIS)

    Gijeon media editorial department

    1977-10-01

    This book is divided into three parts. The first part deals with electricity machine, which can taints from generator to motor, motor a power source of machine tool, electricity machine for machine tool such as switch in main circuit, automatic machine, a knife switch and pushing button, snap switch, protection device, timer, solenoid, and rectifier. The second part handles wiring diagram. This concludes basic electricity circuit of machine tool, electricity wiring diagram in your machine like milling machine, planer and grinding machine. The third part introduces fault diagnosis of machine, which gives the practical solution according to fault diagnosis and the diagnostic method with voltage and resistance measurement by tester.

  13. Turkish electricity reform

    Energy Technology Data Exchange (ETDEWEB)

    Bagdadioglu, Necmiddin [Department of Public Finance, Hacettepe University, 06800 Ankara (Turkey); Odyakmaz, Necmi [E.ON Holding, Armada Business Centre, 06520 Ankara (Turkey)

    2009-03-15

    Turkish electricity reform has progressed slowly due to internal resistance against privatisation, and gained momentum after Electricity Market Law of 2001, prepared in line with EU Energy Acquis and established required institutional and legal framework. Although the eligibility threshold has reached 39% market opening rate, the dominant position of public both as owner and decision-maker is still the major problem in the sector. Currently Turkey is self-sufficient in electricity, but likely to face shortages in 10 years if the growing demand is not met by either speeding the liberalisation process, or joining the South East Europe Electricity Market. (author)

  14. Swiss electricity statistics 2000

    International Nuclear Information System (INIS)

    2001-01-01

    This publication by the Association of Swiss Electricity Enterprises for the Swiss Federal Office of Energy (SFOE) provides statistical information on electricity production, trading and consumption in Switzerland in 2000. Apart from a general overview of the Swiss electricity supply that includes details on power generation, energy transfer with neighbouring countries and data on prices, average consumption and capital investment, the publication also includes graphical representations of electrical energy flows in and out of Switzerland. Tables of data give information on electricity production, import and export for the years 1950 to 2000, the data being supplied for each hydrological year and the summer and winter seasons respectively. The production of power in Switzerland is examined in detail. Details are given on the development of production capacities and the various means of production together with their respective shares of total production. Further tables and diagrams provide information on power production in various geographical regions and on the management of pumped storage hydro-electricity schemes. A further chapter deals in detail with the consumption of electricity, its growth between 1984 and 2000 and its use in various sectors. A fifth chapter examines electricity consumption, generation, import and export on single, typical days, presenting data in tables and diagrams. The next chapter examines energy transfer with foreign countries and the trading structures involved. The final two chapters cover new and future power generation capacities and the economic considerations involved in the supply of electricity

  15. Electricity supply in India

    International Nuclear Information System (INIS)

    Abbott, H.J.

    1993-09-01

    This briefing deals with the electricity supply industry in India in two parts. In the first, the structure and organization of the industry is described under sections dealing with national government involvement, energy policy, state electricity boards, regional electricity boards, state corporations, the private sector and private investment in the power sector including foreign investment. Secondly, the power supply system is described covering generation, plant load factor, non-utility generation, nuclear power, transmission and distribution, system losses and electricity consumption. (8 tables) (UK)

  16. Fire protection electrical engineering

    International Nuclear Information System (INIS)

    Oh, Jung Min

    2000-03-01

    This book concentrates of electricity with current, voltage, power, ohms law, access of resistance, electrolytic analysis and battery, static on frictional electricity and electrostatic induction, coulomb's law, Gauss's law, condenser and capacity, magmatism on magnetic field and magnetic line of force, magnetic circuit, electromagnetic force, electromotive current, basic alternating current circuit, circuit network analysis, three-phase current, non-sinusoidal alternating current, transient phenomena, semiconductor, electric measurement on measurement over resistance, power, power rate and circuit tester, automatic control on introduction, term, classification, foundation of sequence control, logic circuit and basic logic circuit and electric equipment.

  17. Electricity demand in Kazakhstan

    International Nuclear Information System (INIS)

    Atakhanova, Zauresh; Howie, Peter

    2007-01-01

    Properties of electricity demand in transition economies have not been sufficiently well researched mostly due to data limitations. However, information on the properties of electricity demand is necessary for policy makers to evaluate effects of price changes on different consumers and obtain demand forecasts for capacity planning. This study estimates Kazakhstan's aggregate demand for electricity as well as electricity demand in the industrial, service, and residential sectors using regional data. Firstly, our results show that price elasticity of demand in all sectors is low. This fact suggests that there is considerable room for price increases necessary to finance generation and distribution system upgrading. Secondly, we find that income elasticity of demand in the aggregate and all sectoral models is less than unity. Of the three sectors, electricity demand in the residential sector has the lowest income elasticity. This result indicates that policy initiatives to secure affordability of electricity consumption to lower income residential consumers may be required. Finally, our forecast shows that electricity demand may grow at either 3% or 5% per year depending on rates of economic growth and government policy regarding price increases and promotion of efficiency. We find that planned supply increases would be sufficient to cover growing demand only if real electricity prices start to increase toward long-run cost-recovery levels and policy measures are implemented to maintain the current high growth of electricity efficiency

  18. Electric power annual 1992

    Energy Technology Data Exchange (ETDEWEB)

    1994-01-06

    The Electric Power Annual presents a summary of electric utility statistics at national, regional and State levels. The objective of the publication is to provide industry decisionmakers, government policymakers, analysts and the general public with historical data that may be used in understanding US electricity markets. The Electric Power Annual is prepared by the Survey Management Division; Office of Coal, Nuclear, Electric and Alternate Fuels; Energy Information Administration (EIA); US Department of Energy. ``The US Electric Power Industry at a Glance`` section presents a profile of the electric power industry ownership and performance, and a review of key statistics for the year. Subsequent sections present data on generating capability, including proposed capability additions; net generation; fossil-fuel statistics; retail sales; revenue; financial statistics; environmental statistics; electric power transactions; demand-side management; and nonutility power producers. In addition, the appendices provide supplemental data on major disturbances and unusual occurrences in US electricity power systems. Each section contains related text and tables and refers the reader to the appropriate publication that contains more detailed data on the subject matter. Monetary values in this publication are expressed in nominal terms.

  19. Semiconductor Electrical Measurements Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Semiconductor Electrical Measurements Laboratory is a research laboratory which complements the Optical Measurements Laboratory. The laboratory provides for Hall...

  20. Electric engineering summary

    International Nuclear Information System (INIS)

    Kang, Sing Eun; Park, Seong Taek; Lim, Yong Un

    1975-03-01

    This book is made up six parts, which deals with circuit theory about sinusoidal alternating current, basic current circuit, wave power, distorted wave, two terminal network, distributed circuit, laplace transformation and transfer function, power engineering on line, failure analysis transmission of line, substation and protection device and hydroelectric power plant, electricity machine like DC machine, electric transformer, induction machine and rectifier, electromagnetic on dielectric substance current, electromagnetic, electricity application like lighting engineering, heat transfer and electricity chemistry, industry, industry math with integer, rational number, factorization, matrix and differential.

  1. Electrical equipment qualification

    International Nuclear Information System (INIS)

    Farmer, W.S.

    1983-01-01

    Electrical equipment qualification research programs being carried out by CEA, JAERI, and Sandia Laboratories are discussed. Objectives of the program are: (1) assessment of accident simulation methods for electrical equipment qualification testing; lower coarse (2) evaluation of equipment aging and accelerated aging methods; (3) determine radiation dose spectrum to electrical equipment and assess simulation methods for qualification; (4) identify inadequacies in electrical equipment qualification procedures and standards and potential failure modes; and (5) provide data for verifying and improving standards, rules and regulatory guides

  2. Electrical installations and regulations

    CERN Document Server

    Whitfield, J F

    1966-01-01

    Electrical Installations and Regulations focuses on the regulations that apply to electrical installations and the reasons for them. Topics covered range from electrical science to alternating and direct current supplies, as well as equipment for providing protection against excess current. Cables, wiring systems, and final subcircuits are also considered, along with earthing, discharge lighting, and testing and inspection.Comprised of 12 chapters, this book begins with an overview of electrical installation work, traits of a good electrician, and the regulations governing installations. The r

  3. Electric air filtration movie

    International Nuclear Information System (INIS)

    Bergman, W.; Jaeger, R.

    1984-01-01

    The use of electrostatics to improve the performance of conventional air filters has gained considerable attention in recent years. This interest is due to the higher efficiency and reduced pressure drop of electrically enhanced filters compared to conventional fibrous filters. This 30-minute movie presents a state of the art review of electric air filters in the United States with major illustrations provided by the research and development program at the Lawrence Livermore National Laboratory sponsored by the Department of Energy. The electric air filters described in this movie are mechanical air filters to which electrical forces have been added

  4. Electric Field Imaging

    Data.gov (United States)

    National Aeronautics and Space Administration — NDE historically has focused technology development in propagating wave phenomena with little attention to the field of electrostatics and emanating electric fields....

  5. Electrically conductive cellulose composite

    Science.gov (United States)

    Evans, Barbara R.; O'Neill, Hugh M.; Woodward, Jonathan

    2010-05-04

    An electrically conductive cellulose composite includes a cellulose matrix and an electrically conductive carbonaceous material incorporated into the cellulose matrix. The electrical conductivity of the cellulose composite is at least 10 .mu.S/cm at 25.degree. C. The composite can be made by incorporating the electrically conductive carbonaceous material into a culture medium with a cellulose-producing organism, such as Gluconoacetobacter hansenii. The composites can be used to form electrodes, such as for use in membrane electrode assemblies for fuel cells.

  6. Electrical applications 2

    CERN Document Server

    Tyler, David W

    1998-01-01

    Electrical Applications 2 covers the BTEC NII level objectives in Electrical Applications U86/330. To understand the applications, a knowledge of the underlying principles is needed and these are covered briefly in the text. Key topics discussed are: the transmission and distribution of electrical energy; safety and regulations; tariffs and power factor correction; materials and their applications in the electrical industry; transformers; DC machines; illumination; and fuse protection. Included in each chapter are worked examples which should be carefully worked through before progressing to t

  7. Electric vehicle propulsion alternatives

    Science.gov (United States)

    Secunde, R. R.; Schuh, R. M.; Beach, R. F.

    1983-01-01

    Propulsion technology development for electric vehicles is summarized. Analytical studies, technology evaluation, and the development of technology for motors, controllers, transmissions, and complete propulsion systems are included.

  8. The Stephen H. Long Expedition (1819?1820), Titian R. Peale?s field illustrations, and the lost holotypes of the North American shrews Sorex brevicaudus Say and Sorex parvus Say (Mammalia: Soricidae) from the Philadelphia Museum

    Science.gov (United States)

    Woodman, N.

    2009-01-01

    While encamped for the winter of 1819?1820 at Engineer Cantonment along the Missouri River in present-day eastern Nebraska, members of Major Stephen Harriman Long?s Expedition to the Rocky Mountains collected a number of animals that were previously unknown. Among the mammals were two soricids that were subsequently described by Thomas Say as Sorex brevicaudus (Northern Short-tailed Shrew, Blarina brevicauda) and Sorex parvus (Least Shrew, Cryptotis parvus). The holotypes of these species were deposited and placed on public exhibit in the Philadelphia Museum, the predominant North American systematic collection of the early nineteenth century. Like most private museums of that era, the Philadelphia Museum eventually went out of business, and its collections were dispersed and, for the most part, lost. Fortunately, Titian R. Peale made a detailed field sketch of the two specimens soon after their capture and subsequently executed a watercolor based on that sketch. In addition, an engraving of the holotypes was published in the decade following the discovery of the two species. Illustrations of holotypes are taxonomically useful when they depict diagnostic characters of species. They take on added taxonomic significance in the absence of the holotypes. In the cases of Sorex brevicaudus and Sorex parvus, pictures provide strong confirmation of the taxonomic identities of these two species, as well as recording the early history of the specimens.

  9. Allo-SCT for  Philadelphia-negative myeloproliferative neoplasms in blast phase: a study from the Societe Française de Greffe de Moelle et de Therapie Cellulaire (SFGM-TC).

    Science.gov (United States)

    Cahu, X; Chevallier, P; Clavert, A; Suarez, F; Michallet, M; Vincent, L; Vigouroux, S; Blaise, D; Mariette, C; Bilger, K; Robin, M; Yakoub-Agha, I; Peffault de Latour, R; Mohty, M

    2014-06-01

    Progression of Philadelphia-negative myeloproliferative (MPN) or myelodysplastic/myeloproliferative neoplasms (MDS/MPN) to acute myeloid leukemia (AML) is an adverse event in the course of the disease. Although allogeneic hematopoietic SCT (allo-SCT) is considered as the only curative therapy, few data exist on the outcome of patients with Philadelphia-negative MPN or MDS/MPN in blast phase who received an allo-SCT. Sixty patients were included in this retrospective study. AML was secondary to an MPN in 43 cases, whereas AML evolved from an MDS/MPN in 17 cases. Patients received allo-SCT in CR or advanced disease in 26 cases and 34 cases, respectively. With a median follow-up of 31 months (range, 25-44), OS and leukemia-free survival (LFS) were, respectively, 18% and 9% at 3 years. CR at transplant was associated with an improved LFS in univariate and multivariate analysis. The 3-year LFS was 18% for patients undergoing allo-SCT in CR versus 3% in advanced disease (P=0.008). Absence of thrombosis and an intermediate or favorable AML karyotype were associated with an improved outcome for patients who received allo-SCT in CR. New strategies are needed to improve the outcome of patients with MPN-MDS/MPN in blast phase.

  10. Striving for Excellence: Organizational Climate Matters

    Directory of Open Access Journals (Sweden)

    Shelley Phipps

    2013-06-01

    Full Text Available Objective – To describe steps undertaken by the University of Connecticut Libraries to respond to the results of an organizational climate assessment. More than 80% of the Libraries’ staff members completed the ClimateQUAL® survey instrument in the spring of 2007. An organizational development consultant designed a format for focus groups to provide anonymous, but more detailed, experience-based information to help the Libraries discover, understand, and respond to the root causes of “problem” areas indicated by the survey results.Methods – In November 2007, the consultant conducted five 90-minute, on-site focus group sessions, each with 7-15 participants. Two of the sessions were open to all staff members, while the others focused on underrepresented minority group members, team leaders, and the staff of one specific team.Results – A summary report based on compiled data and including recommendations was submitted and discussed with the Libraries’ Leadership Group. In line with organizational development practice, recommendations were made to engage those closest to the “problems” (i.e., the staff to design and recommend improvements to internal systems. The consultant advised the formation of six teams to address internal systems, and an initial three teams comprised of staff members from across the library were formed. These teams were charged with formulating a set of recommended actions that will contribute to a healthier organizational climate in three areas: leadership and team decision making; performance management; and hiring, merit, and promotion. The findings, recommendations, and progress-to-date of each team are summarized.Conclusion – The ClimateQUAL® results and the follow-up with the organizational development consultant helped in identifying potential problem areas within the Libraries’ internal systems. The consultant made recommendations that led to the development of concrete roadmaps, benchmarks, and associated strategies. The Libraries’ progress on its strategic plan will serve as the barometer for gauging the effect of these changes.

  11. Physicists strive to build a black hole

    CERN Multimedia

    Johnson, G

    2001-01-01

    The next generation of particle accelerators, like the LHC, may be able to produce minature black holes. At the same time the experiments will explore the theory that the universe consists of hidden dimensions, outside the three we are familiar with (1 page).

  12. Novel Electrically Small Spherical Electric Dipole Antenna

    DEFF Research Database (Denmark)

    Kim, Oleksiy S.

    2010-01-01

    This paper introduces a novel electrically small spherical meander antenna. Horizontal sections of the meander are composed of wire loops, radii of which are chosen so that the whole structure is conformal to a sphere of radius a. To form the meander the loops are connected by wires at a meridian...

  13. Electricity from wetlands

    NARCIS (Netherlands)

    Wetser, K.

    2016-01-01

    Sustainable electricity generation by the plant microbial fuel cell

    Fossil fuels are currently the main source of electricity production. Combustion of fossil fuels causes air pollution severely affecting human health and nature. This results in an increasing demand for

  14. Unified electricity market

    International Nuclear Information System (INIS)

    Anon

    2011-01-01

    A unified European electricity market means a unification and harmonisation of functioning of the national electricity market into one European Market or into one entity. It gives an opportunity to Slovenske elektrarne to open room for their wider activity within Europe where common rules for cross-boarder trade and markets functioning will apply. (author)

  15. The electricity market

    International Nuclear Information System (INIS)

    2015-01-01

    After a first part proposing predictions for electricity production and consumption for 2016, for the turnovers of electricity suppliers and producers, an indication of important recent important events regarding enterprises belonging to the sector, and a dashboard of the sector activity, an annual report proposes a detailed overview of trends and of the competition context for the electricity market. It identifies the main market opportunities for electricity suppliers, identifies eight determining factors for the sector activity, gives an overview of the sector context evolution between 2004 and 2014 (temperatures, rainfalls, manufacturing industry production, housing and office building stock, projected housing and office building). It analyses the evolution of the sector activity by presenting and commenting various activity indicators and financial performance of electricity producers. It analyses the sector economic structure: evolution of the economic fabric, presentation of various structural characteristics (cross-border exchanges, production capacities per energy source, nuclear plant fleet, thermal plant fleet, location, electricity supply market). It proposes a presentation of the various actors and of their respective market shares, and presentations of groups, electricity suppliers, and electricity producers. It indicates highlights and presents various rankings of the main enterprises in 2014

  16. Electric industry in 1992

    International Nuclear Information System (INIS)

    1993-01-01

    The production of electricity in 1992 is analyzed. The increase (0,4%) of electricity consumption and the decrease of its production are the main characteristics of 1993 in Spain. These aspect with the UNESA data are studied. In 1992 30000 Kw of 216.505 Kw total were produced by wind mills

  17. Electric power annual, 1991

    International Nuclear Information System (INIS)

    1993-01-01

    The Electric Power Annual is prepared by the Survey Management Division; Office of Coal, Nuclear, Electric and Alternate Fuels; Energy Information Administration (EIA); US Department of Energy. The 1991 edition has been enhanced to include statistics on electric utility demand-side management and nonutility supply. ''The US Electric Power Industry at a Glance'' section presents a profile of the electric power industry ownership and performance, and a review of key statistics for the year. Subsequent sections present data on generating capability, including proposed capability additions; net generation; fossil-fuel statistics; electricity sales, revenue, and average revenue per kilowatthour sold; financial statistics; environmental statistics; electric power transactions; demand-side management; and nonutility power producers. In addition, the appendices provide supplemental data on major disturbances and unusual occurrences in US electricity power systems. Each section contains related text and tables and refers the reader to the appropriate publication that contains more detailed data on the subject matter. Monetary values in this publication are expressed in nominal terms

  18. Electricity information 1994

    International Nuclear Information System (INIS)

    1995-01-01

    Basic statistics on the electricity and heat production in OECD countries are compiled by the International Energy Agency. The statistics cover annual OECD data for prices, production, consumption and trade. Detailed electricity and heat statistics are also presented for each OECD countries. (O.L.). 34 figs., 36 tabs

  19. Sustainable Use of Electricity

    DEFF Research Database (Denmark)

    Nørgaard, Jørgen

    1998-01-01

    An overview is presented of the need for keeping electricity consumption low, including a suggested definition of sustainable development. Specific attention is devoted to present and future electricity production´s contribution to the environmental problems. Prognoses are shown from before any...

  20. The harnessing of electricity

    International Nuclear Information System (INIS)

    Valencia Giraldo, Asdrubal

    1992-01-01

    A brief summary is presented on the evolution of electricity knowledge from antiquity to our days. At the same time the growth of its practical applications, i. e. the electrical industry, is described, as well as its technical, scientific, economic and social consequences

  1. Electric Vehicle Battery Challenge

    Science.gov (United States)

    Roman, Harry T.

    2014-01-01

    A serious drawback to electric vehicles [batteries only] is the idle time needed to recharge their batteries. In this challenge, students can develop ideas and concepts for battery change-out at automotive service stations. Such a capability would extend the range of electric vehicles.

  2. Hawaii Electric System Reliability

    Energy Technology Data Exchange (ETDEWEB)

    Loose, Verne William [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Silva Monroy, Cesar Augusto [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2012-08-01

    This report addresses Hawaii electric system reliability issues; greater emphasis is placed on short-term reliability but resource adequacy is reviewed in reference to electric consumers’ views of reliability “worth” and the reserve capacity required to deliver that value. The report begins with a description of the Hawaii electric system to the extent permitted by publicly available data. Electrical engineering literature in the area of electric reliability is researched and briefly reviewed. North American Electric Reliability Corporation standards and measures for generation and transmission are reviewed and identified as to their appropriateness for various portions of the electric grid and for application in Hawaii. Analysis of frequency data supplied by the State of Hawaii Public Utilities Commission is presented together with comparison and contrast of performance of each of the systems for two years, 2010 and 2011. Literature tracing the development of reliability economics is reviewed and referenced. A method is explained for integrating system cost with outage cost to determine the optimal resource adequacy given customers’ views of the value contributed by reliable electric supply. The report concludes with findings and recommendations for reliability in the State of Hawaii.

  3. Hawaii electric system reliability.

    Energy Technology Data Exchange (ETDEWEB)

    Silva Monroy, Cesar Augusto; Loose, Verne William

    2012-09-01

    This report addresses Hawaii electric system reliability issues; greater emphasis is placed on short-term reliability but resource adequacy is reviewed in reference to electric consumers' views of reliability %E2%80%9Cworth%E2%80%9D and the reserve capacity required to deliver that value. The report begins with a description of the Hawaii electric system to the extent permitted by publicly available data. Electrical engineering literature in the area of electric reliability is researched and briefly reviewed. North American Electric Reliability Corporation standards and measures for generation and transmission are reviewed and identified as to their appropriateness for various portions of the electric grid and for application in Hawaii. Analysis of frequency data supplied by the State of Hawaii Public Utilities Commission is presented together with comparison and contrast of performance of each of the systems for two years, 2010 and 2011. Literature tracing the development of reliability economics is reviewed and referenced. A method is explained for integrating system cost with outage cost to determine the optimal resource adequacy given customers' views of the value contributed by reliable electric supply. The report concludes with findings and recommendations for reliability in the State of Hawaii.

  4. French electricity report 2003

    International Nuclear Information System (INIS)

    2003-01-01

    In terms of electricity, 2003 saw a great increase in electricity consumption in France. This increase was accompanied by a global progression in cross-border commercial exchanges, but a notable drop in the net export balance for physical exchanges between France and its neighbouring countries

  5. Pulsed electric fields

    Science.gov (United States)

    The concept of pulsed electric fields (PEF) was first proposed in 1967 to change the behavior or microorganisms. The electric field phenomenon was identified as membrane rupture theory in the 1980s. Increasing the membrane permeability led to the application of PEF assisted extraction of cellular co...

  6. Load leveling efforts of The Hokkaido Electric Power Co. Inc.; Hokkaido Denryoku no fuka heijunka eno torikumi ni tsuite

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-04-01

    The Hokkaido Electric Power Co., Inc., aiming to enhance power generation efficiency through power load levelling, strives to expand and substantiate its electricity billing menu and to popularize and encourage the use of levelling-oriented apparatuses and systems most of which are designed for utilizing midnight power. The billing menu has in it a snow-melting power which is cut off for load levelling during the peak demand time zone. For domestic use, a time zone-specified lighting system named Dream Eight is created, which is one of the billing systems dependent upon time zone. Introduced therein for industrial use is a demand/supply adjustment contract system. Furthermore, in compliance with the amended Electricity Business Law that came into force in 1995, efforts are under way for revising the period wherein power is to be supplied for melting snow, expanding the scope of application of the power supply system dependent upon time zone, and newly introducing a heat accumulation assisted peak adjustment contract system and an operation adjustment contract system. As for business efforts in relation to load levelling, the company proposes household electrical systems centering about 200V high-efficiency apparatuses, electric water warmer contributing to the enhancement of year-round load levelling, popularization and reinforcement of electric snow melting systems, and power utilizing technologies capable of meeting local demands raised for example by agriculture and fishery.

  7. Analysis of environmental impacts of renewable energy on the Moroccan electricity sector: A System Dynamics approach

    Science.gov (United States)

    Chentouf, M.; Allouch, M.

    2018-05-01

    Producing electricity at an affordable price while taking into account environmental concerns has become a major challenge in Morocco. Moreover, the technical and financial issues related to renewable electricity plants are still hindering their efficient integration in the country. In fact, the energy sector (both electricity and heat) accounted for more than half of all Greenhouse Gases (GHG) emissions in the kingdom due to the major reliance on fossil fuels for answering the growing local demand. The key strategies to alleviate this critical situation include the integration of more renewable energies in the total energy mix and the enhancement of energy efficiency measures in different sectors. This paper strives to (1) evaluate the potential of carbon dioxide mitigation in Moroccan electricity sector following the actual and projected strategies and (2) highlight the policy schemes to be taken in order to achieve the ambitious carbon dioxide mitigation targets in the mid-term. A system dynamics model was built in order to simulate different scenarios of carbon dioxide mitigation policies up to 2030. The results shows that the achievement of renewable energies projects by 2030 could save 228.143 MtCO2 between 2020 and 2030 and an additional 18.127 MtCO2 could be avoided in the same period by enhancing energy efficiency measures.

  8. Simulation of the electric potential and plasma generation coupling in magnetron sputtering discharges

    Science.gov (United States)

    Trieschmann, Jan; Krueger, Dennis; Schmidt, Frederik; Brinkmann, Ralf Peter; Mussenbrock, Thomas

    2016-09-01

    Magnetron sputtering typically operated at low pressures below 1 Pa is a widely applied deposition technique. For both, high power impulse magnetron sputtering (HiPIMS) as well as direct current magnetron sputtering (dcMS) the phenomenon of rotating ionization zones (also referred to as spokes) has been observed. A distinct spatial profile of the electric potential has been associated with the latter, giving rise to low, mid, and high energy groups of ions observed at the substrate. The adherent question of which mechanism drives this process is still not fully understood. This query is approached using Monte Carlo simulations of the heavy particle (i.e., ions and neutrals) transport consistently coupled to a pre-specified electron density profile via the intrinsic electric field. The coupling between the plasma generation and the electric potential, which establishes correspondingly, is investigated. While the system is observed to strive towards quasi-neutrality, distinct mechanisms governing the shape of the electric potential profile are identified. This work is supported by the German Research Foundation (DFG) in the frame of the transregional collaborative research centre TRR 87.

  9. Materials and electricity

    International Nuclear Information System (INIS)

    Jaffee, R.I.

    1986-01-01

    Despite an increase in the intensity of electricity usage, electricity has been reversing its historical trend of reduced cost since 1970 to the point where costs are increasing faster than inflation. Designers and operators on both sides of the meter and the developers of materials from which the electric system is constructed must contribute to the lowering of costs and an increase in reliability for the generation, transmission and distribution, and utilization of electricity. Four specific cases illustrate the role of materials/process improvements to this end. The examples highlight the use of forged or welded integral rotors, improvements in the heat rate of coal-fired plants through higher steam conditions and reduced heat losses, reduced losses through amorphous steel cores for transformers, and reduced ac electric motor losses through silicon variable speed drives. 37 references, 27 figures, 9 tables

  10. Electric automobile: Commercialization prospects

    International Nuclear Information System (INIS)

    Tabasso, L.

    1992-01-01

    Performance results during one-month test driving of a small FIAT car (normally equipped with a 30-45 Hp internal combustion engine), retrofitted to operate with a set of electric batteries delivering 15 Hp, demonstrated that, unless the design of an electric car's transmission and control systems are based completely on electric power operation, the vehicle loses its competitiveness with conventional cars. Making reference to the findings of an ENEA (Italian Agency for New Technology, Energy and Environment) electric powered vehicle R ampersand D program, this paper assesses the feasibility of electric powered vehicles and points out their major drawbacks: battery volume, weight, cost and recharging requirements in densely populated urban environments. The paper also notes that mass conversion to these vehicles by itself will not solve the urban traffic congestion problem for which optimum traffic control and parking areas are required

  11. Electricity Storage. Technology Brief

    Energy Technology Data Exchange (ETDEWEB)

    Simbolotti, G. [Italian National Agency for New Technologies, Energy and Sustainable Economic Development ENEA, Rome (Italy); Kempener, R. [International Renewable Energy Agency IRENA, Bonn (Germany)

    2012-04-15

    Electricity storage is a key technology for electricity systems with a high share of renewables as it allows electricity to be generated when renewable sources (i.e. wind, sunlight) are available and to be consumed on demand. It is expected that the increasing price of fossil fuels and peak-load electricity and the growing share of renewables will result in electricity storage to grow rapidly and become more cost effective. However, electricity storage is technically challenging because electricity can only be stored after conversion into other forms of energy, and this involves expensive equipment and energy losses. At present, the only commercial storage option is pumped hydro power where surplus electricity (e.g. electricity produced overnight by base-load coal or nuclear power) is used to pump water from a lower to an upper reservoir. The stored energy is then used to produce hydropower during daily high-demand periods. Pumped hydro plants are large-scale storage systems with a typical efficiency between 70% and 80%, which means that a quarter of the energy is lost in the process. Other storage technologies with different characteristics (i.e. storage process and capacity, conversion back to electricity and response to power demand, energy losses and costs) are currently in demonstration or pre-commercial stages and discussed in this brief report: Compressed air energy storage (CAES) systems, Flywheels; Electrical batteries; Supercapacitors; Superconducting magnetic storage; and Thermal energy storage. No single electricity storage technology scores high in all dimensions. The technology of choice often depends on the size of the system, the specific service, the electricity sources and the marginal cost of peak electricity. Pumped hydro currently accounts for 95% of the global storage capacity and still offers a considerable expansion potential but does not suit residential or small-size applications. CAES expansion is limited due to the lack of suitable

  12. Ontario electricity industry restructuring

    International Nuclear Information System (INIS)

    1999-01-01

    The objective of Ontario's electricity industry restructuring was described as an effort to enhance Ontario's competitiveness. It is believed that restructuring can be accomplished without an increase in electricity rates. In a series of charts, the report provides the timeline of restructuring from the time of the Macdonald report in 1995 to the beginning of open competition in Ontario electricity markets. It oulines the principles underlying the financial restructuring and the financial results of restructuring, including the size of the stranded debt ($ 7.8 billion). It lists the changes that have occurred since October 1998, explains some key factors in valuing the successor companies and profiles the Ontario Electricity Financial Corporation. Restructuring of the industry is expected to have a neutral to positive impact on Ontario's fiscal position. The residual stranded debt of $7.8 billion will be retired through revenues generated by the electricity sector, without recourse to the Provincial Treasury. 9 figs

  13. Electric power monthly

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Sandra R.; Johnson, Melvin; McClevey, Kenneth; Calopedis, Stephen; Bolden, Deborah

    1992-05-01

    The Electric Power Monthly is prepared by the Survey Management Division; Office of Coal, Nuclear, Electric and Alternate Fuels, Energy Information Administration (EIA), Department of Energy. This publication provides monthly statistics at the national, Census division, and State levels for net generation, fuel consumption, fuel stocks, quantity and quality of fuel, cost of fuel, electricity sales, revenue, and average revenue per kilowatthour of electricity sold. Data on net generation, fuel consumption, fuel stocks, quantity and cost of fuel are also displayed for the North American Electric Reliability Council (NERC) regions. Additionally, statistics by company and plant are published in the EPM on capability of new plants, new generation, fuel consumption, fuel stocks, quantity and quality of fuel, and cost of fuel.

  14. Electricity/oil substitution

    International Nuclear Information System (INIS)

    Melvin, J.G.

    1980-09-01

    The extent to which electricity could substitute for imported oil in Canada is assessed and it is concluded that the bulk of projected oil imports could be displaced. This substitution of electricity for oil could be largely completed within two decades, with existing technology, using Canadian resources. The substitution of electricity for imported oil would result in relatively low energy costs and would stimulate economic growth. Energy self-sufficiency through the substitution of electricity for oil is uniquely a Canadian option; it is not open to other industrial countries. The option exists because of Canada's resources of oil sands for essential liquid fuels, hydraulic and nuclear electrical potential, and natural gas as an interim source of energy. While other countries face an energy crisis due to declining supplies of oil, Canada faces opportunities. The policies of Federal and Provincial governments, as perceived by individual decision makers, will have a major influence on Canada's ability to realize opportunities. (auth)

  15. Earth's electric field

    International Nuclear Information System (INIS)

    Kelley, M.C.

    1978-01-01

    The earth becomes charged during thunderstorm activity and discharges through the weak conducting atmosphere. Balloon and rocket studies infer that a high altitude electric field penetrates virtually unattenuated through the atmosphere, at least as far as balloon heights. The field has two primary sources. At low and mid latitudes, interaction between the earth's magnetic field and the neutral wind creates electric fields. At latitudes above 60 0 , the high altitude electrical structure is dominated by the interaction between the solar wind and the earth's magnetic field. The auroral light is emitted by atmospheric atoms and molecules excited by electrons with potentials of many thousands volts. The potentials are induced by the solar wind. Recent satellite data shows that the electrons get this energy by passing through a localized electric field about 6000 km above the auroral zone. Several rocket and satellite experiments used to study the earth's electric field are discussed

  16. Electricity Bill [second reading

    International Nuclear Information System (INIS)

    Hooper, G.; Williams, C.C.P.; Ezra, D.

    1989-01-01

    The Parliamentary Under-Secretary at the Department of Energy introduced the second reading of the Electricity Bill which provides for the restructuring and privatisation of the electricity supply industry throughout Great Britain. Three features at the heart of the Government's proposals are mentioned - first that the proposals will promote competition in electricity generation and supply of electricity so there will be a downward pressure on costs and prices, second is a new deal for customers and third is the security of electricity supply which will be ensured by the diversity of suppliers. The benefits of the scheme are outlined and then specific details of the Bill are considered. The debate which followed lasted six hours and is reported verbatim. The issues raised included environmental effects, efficiency, energy conservation, research and development and investment. (UK)

  17. Swiss electricity statistics 2001

    International Nuclear Information System (INIS)

    2002-01-01

    This publication by the Association of Swiss Electricity Enterprises for the Swiss Federal Office of Energy (SFOE) provides statistical information on electricity production, trading and consumption in Switzerland in 2001. Apart from a general overview of the Swiss electricity supply that includes details on power generation, energy transfer with neighbouring countries and data on prices, average consumption and capital investment, the publication also includes graphical representations of electrical energy flows in and out of Switzerland. Tables of data give information on electricity production, import and export for the years 1950 to 2001, the data being supplied for each hydrological year and the summer and winter seasons respectively. The production of power in Switzerland is examined in detail. Details are given on the development of production capacities and the various means of production together with their respective shares of total production. Further tables and diagrams provide information on power production in various geographical regions and on the management of pumped storage hydro-electricity schemes. A further chapter deals in detail with the consumption of electricity, its growth between 1984 and 2001 and its use in various sectors. A fifth chapter examines electricity consumption, generation, import and export on single, typical days, presenting data in tables and diagrams. The next chapter examines energy transfer with foreign countries and the trading structures involved. The final two chapters cover new and future power generation capacities and the economic considerations involved in the supply of electricity chapters cover new and future power generation capacities and the economic considerations involved in the supply of electricity

  18. EDITORIAL: Adaptive and active materials: Selected papers from the ASME 2010 Conference on Smart Materials, Adaptive Structures and Intelligent Systems (SMASIS 10) (Philadelphia, PA, USA, 28 September-1 October 2010) Adaptive and active materials: Selected papers from the ASME 2010 Conference on Smart Materials, Adaptive Structures and Intelligent Systems (SMASIS 10) (Philadelphia, PA, USA, 28 September-1 October 2010)

    Science.gov (United States)

    Brei, Diann

    2011-09-01

    The third annual meeting of the AMSE/AIAA Smart Materials, Adaptive Structures and Intelligent Systems Conference (SMASIS) took place in the heart of historic Philadelphia's cultural district, and included a pioneer banquet in the National Constitutional Center. The applications emphasis of the 2010 conference was reflected in keynote talks by Dr Alan Taub, vice president of General Motors global research and development, 'Smart materials in the automotive industry'; Dr Charles R Farrar, engineering institute leader at Los Alamos National Laboratory, 'Future directions for structural health monitoring of civil engineering infrastructure'; and Professor Christopher S Lynch of the University of California Los Angeles, 'Ferroelectric materials and their applications'. The SMASIS conference was divided into six technical symposia each of which included basic research, applied technological design and development, and industrial and governmental integrated system and application demonstrations. The six symposia were: SYMP 1 Multifunctional Materials; SYMP 2 Active Materials, Mechanics and Behavior; SYMP 3 Modeling, Simulation and Control; SYMP 4 Enabling Technologies and Integrated System Design; SYMP 5 Structural Health Monitoring/NDE; and SYMP 6 Bio-inspired Smart Materials and Structures. In addition, the conference introduced a new student and young professional development symposium. Authors of papers in the materials areas (symposia 1, 2 and 6) were invited to write a full journal article on their presentation topic for publication in this special issue of Smart Materials and Structures. This set of papers demonstrates the exceptional quality and originality of the conference presentations. We are appreciative of their efforts in producing this collection of highly relevant articles on smart materials.

  19. Electricity from biogas

    International Nuclear Information System (INIS)

    Augenstein, D.; Benemann, J.; Hughes, E.

    1994-01-01

    Biogas is a medium-Btu methane and carbon dioxide mix produced by bacterial decomposition of organic matter. Its sources include landfills, waste water sludges, and animal wastes. It can fuel energy applications, of which electricity generation is a frequently-preferred option. The greatest current U.S. biogas recovery and energy use is at landfills, where biogas at about 80 landfill sites fuels a total of approximately 300 MWe. Wastewater treatment plants and confined animal waste management systems support additional electric power production. Generation of electricity from biogas can present difficulties due to the generally small scale of the generating facility, variable energy content of the gas, fluctuating availability, contaminant problems, and often-demanding control needs. However, such difficulties are being successfully addressed and economics for electricity generation are often favorable as biogas can be essentially open-quotes freeclose quotes fuel. Biogas recovery and use has the additional advantage of mitigating a potent greenhouse gas. Biogas from U.S. landfills alone could fuel about 1% of U.S. electrical generation while giving climate change benefit equivalent to reducing CO 2 emissions in the electricity sector by more than 10%. Growth in landfill gas use will be facilitated by recent regulations, advances in equipment, and improved management techniques such as open-quotes controlled landfillingclose quotes. The potential for biogas recovery and electricity production from sewage sludges, animal wastes and other organic resources such as agricultural residues is uncertain but probably exceeds the estimate for landfills

  20. Electricity and the environment

    International Nuclear Information System (INIS)

    1991-09-01

    The objective of the Symposium was to provide a comprehensive assessment of the environmental and health factors as well as the economic factors involved in supplying electricity services, and to suggest a framework within which these issues should be taken into account in making future plans and decisions on electricity production and use. The potential role of different ways of meeting electricity service requirements was also to be analysed, taking into consideration both demand side and supply side options in the light of their comparative economic, environmental and health related impacts. Four Expert Groups considered key issues: the environmental implications of energy and electricity supply and demand; energy sources and technologies for electricity generation; comparative environmental and health effects of different energy systems for electricity generation; and the incorporation of environmental and health impacts into policy, planning and decision making for the electricity sector. During the Symposium, keynote addresses and invited papers presented by leading experts and policy makers provided additional related information. In this volume the background papers are presented. The proceedings have been published separately, and the individual papers in both volumes have been indexed separately for INIS. Refs, figs and tabs

  1. Electricity and the environment

    International Nuclear Information System (INIS)

    1991-01-01

    The objective of the Symposium was to provide a comprehensive assessment of the environmental and health factors as well as the economic factors involved in supplying electricity services, and to suggest a framework within which these issues should be taken into account in making future plans and decisions on electricity production and use. The potential role of different ways of meeting electricity service requirements was also to be analysed, taking into consideration both demand side and supply side options in the light of their comparative economic, environmental and health related impacts. Four Expert Groups considered key issues: the environmental implications of energy and electricity supply and demand; energy sources and technologies for electricity generation; comparative environmental and health effects of different energy systems for electricity generation; and the incorporation of environmental and health impacts into policy, planning and decision making for the electricity sector. During the Symposium, keynote addresses and invited papers presented by leading experts and policy makers provided additional related information. The Proceedings contain all the addresses and papers presented (which are also indexed separately) together with summaries of the discussions that took place. The Key Issues Papers are presented in a separate publication. Refs, figs and tabs

  2. Electric power distribution handbook

    CERN Document Server

    Short, Thomas Allen

    2014-01-01

    Of the ""big three"" components of electrical infrastructure, distribution typically gets the least attention. In fact, a thorough, up-to-date treatment of the subject hasn't been published in years, yet deregulation and technical changes have increased the need for better information. Filling this void, the Electric Power Distribution Handbook delivers comprehensive, cutting-edge coverage of the electrical aspects of power distribution systems. The first few chapters of this pragmatic guidebook focus on equipment-oriented information and applications such as choosing transformer connections,

  3. Electric distribution systems

    CERN Document Server

    Sallam, A A

    2010-01-01

    "Electricity distribution is the penultimate stage in the delivery of electricity to end users. The only book that deals with the key topics of interest to distribution system engineers, Electric Distribution Systems presents a comprehensive treatment of the subject with an emphasis on both the practical and academic points of view. Reviewing traditional and cutting-edge topics, the text is useful to practicing engineers working with utility companies and industry, undergraduate graduate and students, and faculty members who wish to increase their skills in distribution system automation and monitoring."--

  4. Dielectrics in electric fields

    CERN Document Server

    Raju, Gorur G

    2003-01-01

    Discover nontraditional applications of dielectric studies in this exceptionally crafted field reference or text for seniors and graduate students in power engineering tracks. This text contains more than 800 display equations and discusses polarization phenomena in dielectrics, the complex dielectric constant in an alternating electric field, dielectric relaxation and interfacial polarization, the measurement of absorption and desorption currents in time domains, and high field conduction phenomena. Dielectrics in Electric Fields is an interdisciplinary reference and text for professionals and students in electrical and electronics, chemical, biochemical, and environmental engineering; physical, surface, and colloid chemistry; materials science; and chemical physics.

  5. Electrical principles 3 checkbook

    CERN Document Server

    Bird, J O

    2013-01-01

    Electrical Principles 3 Checkbook aims to introduce students to the basic electrical principles needed by technicians in electrical engineering, electronics, and telecommunications.The book first tackles circuit theorems, single-phase series A.C. circuits, and single-phase parallel A.C. circuits. Discussions focus on worked problems on parallel A.C. circuits, worked problems on series A.C. circuits, main points concerned with D.C. circuit analysis, worked problems on circuit theorems, and further problems on circuit theorems. The manuscript then examines three-phase systems and D.C. transients

  6. Intelligent Electricity Broker

    DEFF Research Database (Denmark)

    Grode, Jesper Nicolai Riis; Væggemose, Poul Erik; Kulik, Tomas

    The Intelligent Electricity Broker (IEB) is a new energy storage and energy broker facility that serves two purposes. Firstly, it allows for storing excessive energy in the Smart Grid [1, 2, 3] it is connected to. Secondly, it runs a broker-algorithm that ensures that energy is purchased and sold...... when feasible to the system owner. This paper describes how the IEB can be used by house owners, in building clusters, and/or by energy providers to take advantage of electricity stock market prices and weather forecasts to control energy surplus storage suffers as well as to lower electricity bills...

  7. Electric power substations engineering

    CERN Document Server

    McDonald, John D

    2012-01-01

    The use of electric power substations in generation, transmission, and distribution remains one of the most challenging and exciting areas of electric power engineering. Recent technological developments have had a tremendous impact on all aspects of substation design and operation. With 80% of its chapters completely revised and two brand-new chapters on energy storage and Smart Grids, Electric Power Substations Engineering, Third Edition provides an extensive updated overview of substations, serving as a reference and guide for both industry and academia. Contributors have written each chapt

  8. Shipboard electrical power systems

    CERN Document Server

    Patel, Mukund R

    2011-01-01

    Shipboard Electrical Power Systems addresses new developments in this growing field. Focused on the trend toward electrification to power commercial shipping, naval, and passenger vessels, this book helps new or experienced engineers master cutting-edge methods for power system design, control, protection, and economic use of power. Provides Basic Transferable Skills for Managing Electrical Power on Ships or on LandThis groundbreaking book is the first volume of its kind to illustrate optimization of all aspects of shipboard electrical power systems. Applying author Mukund Patel's rare combina

  9. Geothermal electricity generation

    International Nuclear Information System (INIS)

    Eliasson, E.T.

    1991-01-01

    Geothermal conversion, as discussed here, is the conversion of the heat bound within the topmost three kilometres of the upper crust of the earth into useful energy, principally electricity. The characteristics of a geothermal reservoir and its individual technical features are highly site-specific. Applications therefore must be designed to match the specific geothermal reservoir. An estimate of the electric energy potential world-wide made by the Electric Power Research Institute (United States) in 1978 and based on sustaining a continuous 30-year operation is given in the box at the right for comparison purposes only. 8 refs, 5 figs

  10. Electric scooter pilot project

    Science.gov (United States)

    Slanina, Zdenek; Dedek, Jan; Golembiovsky, Matej

    2016-09-01

    This article describes the issue of electric scooter development for educational and demonstration purposes on the Technical University of Ostrava. Electric scooter is equipped with a brushless motor with permanent magnets and engine controller, measuring and monitoring system for speed regulation, energy flow control and both online and off-line data analysis, visualization system for real-time diagnostics and battery management with balancing modules system. Implemented device brings a wide area for the following scientific research. This article also includes some initial test results and electric vehicles experiences.

  11. Electricity from biomass

    International Nuclear Information System (INIS)

    Price, B.

    1998-11-01

    Electricity from biomass assesses the potential of biomass electricity for displacing other more polluting power sources and providing a relatively clean and ecologically friendly source of energy; discusses its environmental and economic effects, while analysing political and institutional initiatives and constraints; evaluates key factors, such as energy efficiency, economics, decentralisation and political repurcussions; considers the processes and technologies employed to produce electricity from biomass; and discusses the full range of incentives offered to producers and potential producers and the far-reaching implications it could have for industry, society and the environment. (author)

  12. Hot dry rock geothermal energy for U.S. electric utilities. Draft final report

    Energy Technology Data Exchange (ETDEWEB)

    1993-06-01

    In order to bring an electric utility component into the study of hot dry rock geothermal energy called for in the Energy Policy Act of 1992 (EPAct), EPRI organized a one-day conference in Philadelphia on January 14,1993. The conference was planned as the first day of a two-day sequence, by coordinating with the U.S. Geological Survey (USGS) and the U.S. Department of Energy (DOE). These two federal agencies were charged under EPAct with the development of a report on the potential for hot dry rock geothermal energy production in the US, especially the eastern US. The USGS was given lead responsibility for a report to be done in association with DOE. The EPRI conference emphasized first the status of technology development and testing in the U.S. and abroad, i.e., in western Europe, Russia and Japan. The conference went on to address the extent of knowledge regarding the resource base in the US, especially in the eastern half of the country, and then to address some practical business aspects of organizing projects or industries that could bring these resources into use, either for thermal applications or for electric power generation.

  13. Electric power in Canada 1993

    International Nuclear Information System (INIS)

    1994-01-01

    The electric power industry in Canada in 1993 is reviewed. Items discussed include: the international context of Canadian electricity; regulatory structures; electricity and the environment; electricity consumption; electricity generation; generating capacity and reserve; electricity trade; transmission; electric utility investment and financing; costing and pricing; electricity outlook; demand-side management; and non-utility generation. Appended information is presented on installed capacity and electrical energy consumption in Canada, installed generating capacity, conventional thermal capacity by principal fuel type, provincial electricity imports and exports, Canadian electricity exports by exporter and importer, generation capacity by type, installed generating capacity expansion in Canada by station, federal environmental standards and guidelines, and prices paid by major electric utilities for non-utility generation. 23 figs., 95 tabs

  14. Electric power in Canada 1992

    International Nuclear Information System (INIS)

    1993-01-01

    The electric power industry in Canada in 1991 is reviewed. Items discussed include: the international context of Canadian electricity; regulatory structures; electricity and the environment; electricity consumption; electricity generation; generating capacity and reserve; electricity trade; transmission; electric utility investment and financing; costing and pricing; electricity outlook; demand-side management; and non-utility generation. Appended information is presented on installed capacity and electrical energy consumption in Canada, installed generating capacity, conventional thermal capacity by principal fuel type, provincial electricity imports and exports, Canadian electricity exports by exporter and importer, generation capacity by type, installed generating capacity expansion in Canada by station, federal environmental standards and guidelines, and prices paid by major electric utilities for non-utility generation. 26 figs., 90 tabs

  15. Electric power in Canada 1993

    International Nuclear Information System (INIS)

    1994-01-01

    The electric power industry in Canada in 1993 is reviewed. Items discussed include: the international context of Canadian electricity; regulatory structures; electricity and the environment; electricity consumption; electricity generation; generating capacity and reserve; electricity trade; transmission; electric utility investment and financing; costing and pricing; electricity outlook; demand-side management; and non-utility generation. Information is appended on installed capacity and electrical energy consumption in Canada, installed generating capacity, conventional thermal capacity by principal fuel type, provincial electricity imports and exports, Canadian electricity exports by exporter and importer, generation capacity by type, installed generating capacity expansion in Canada by station, federal environmental standards and guidelines, and prices paid by major electric utilities for non-utility generation. 26 figs., 90 tabs

  16. Sensible production processes with electricity

    Energy Technology Data Exchange (ETDEWEB)

    Eerola, P.; Annala, T.; Wickstroem, T. [ed.

    1997-11-01

    Small and medium-sized industrial enterprises use electricity increasingly for both heating and production, as electricity offers easy adjustability and has little need for maintenance. In production processes, the advantages of electricity also include uniform quality, automation and cleanness

  17. The electricity market 2002

    International Nuclear Information System (INIS)

    2002-01-01

    The purpose of the 'Electricity market 2002' publication is to meet the need for generalized and readily accessible information on the conditions on the Nordic market. Iceland is not included in the description. The publication also includes summaries of information from recent years concerning electricity generation and utilization in the Nordic countries, the structure of the electricity market from the players' perspective, trade in electricity in the Nordic countries and in Northern Europe, electricity prices in the Nordic and other countries, and the impact of the electricity sector on the environment. The publication contains data on electricity generation and use during the past years, structure of the electricity market, trade in electricity in the Nordic countries and northern Europe, electricity prices in the Nordic countries and other countries as well as impact of electricity generation system on the environment. The market price of electricity is affected by a number of factors, including fuel prices, availability of water, and the power and energy balances of the various countries. The availability of water in Norway and Sweden has been very good in recent years, which has had a major influence on the price. 1996 was a dry year, which led to a high system price on Nord Pool. The price of electricity then dropped and has remained at a relatively low level up to the year 2001. The price of electricity rose during the spring of 2001 and remained at a higher level also during the summer months. The main reason was that the availability of water was lower than normal in Norway during the early part of the year. This created a higher demand for imported electricity in Norway and caused some apprehension that the year would be dry. The total price of electricity to the end users has not followed the system price development. The total cost of electricity to the end consumers consists of three items, i.e. the price of electricity, the network charges and

  18. An encyclopedia on domestic electricity

    International Nuclear Information System (INIS)

    1982-12-01

    This book describes the footprint of domestic electrification with domestic energy and the role of electrification, basic knowledge on domestic electrification, the basic things electric equipment in domestic, materials, part and making, demand of electricity, electrification and life, various electric equipment in the kitchen, rationalization of house chore, environment and hygiene like electric iron, electric stove, electric mat and dining wagon, beauty treatment and health, refinement and entertainment and lighting in houses.

  19. Electricity : Italian style

    International Nuclear Information System (INIS)

    Murray, L.

    2007-01-01

    Italy's electricity system was described. Italy relies on outside sources for between 10 and 15 per cent of its electricity supply. Most Italians use gas, wood stoves and fossil fuels, and are conservative about lighting. Electricity costs more in Italy than in any other European country. Italy made the decision to decommission its nuclear power stations after Chernobyl. In 2005, Italy's largest utility group signed a memorandum of understanding ensuring that they would contract energy from France's nuclear reactors. Italy is now financing and managing projects in Russia and eastern Europe, and has strengthened its ties in Spain and the Netherlands. Although Italy is intent on producing its own power, the perceptions of health hazards from electricity towers cause citizens to strongly protest new installations. It was concluded that rising energy prices may force Italians to reconsider the use of alternative energy sources. 3 figs

  20. Electrically conductive material

    Science.gov (United States)

    Singh, J.P.; Bosak, A.L.; McPheeters, C.C.; Dees, D.W.

    1993-09-07

    An electrically conductive material is described for use in solid oxide fuel cells, electrochemical sensors for combustion exhaust, and various other applications possesses increased fracture toughness over available materials, while affording the same electrical conductivity. One embodiment of the sintered electrically conductive material consists essentially of cubic ZrO[sub 2] as a matrix and 6-19 wt. % monoclinic ZrO[sub 2] formed from particles having an average size equal to or greater than about 0.23 microns. Another embodiment of the electrically conductive material consists essentially at cubic ZrO[sub 2] as a matrix and 10-30 wt. % partially stabilized zirconia (PSZ) formed from particles having an average size of approximately 3 microns. 8 figures.

  1. Electric transmission technology

    International Nuclear Information System (INIS)

    Shah, K.R.

    1990-01-01

    Electric transmission technology has matured and can transmit bulk power more reliably and economically than the technology 10 years ago.In 1882, Marcel Depres transmitted 15 kW electric power at 2 kV, using a constant direct current; present transmission voltages have risen to ± 600 kV direct current (DC) and 765 kV alternating current (AC), and it is now possible to transmit bulk electric power at voltages as high as ± 1000 kV DC and 1500 kV AC. Affordable computer systems are now available to optimize transmission reliably. New materials have reduced the bulk of insulation for lines and equipment. New conducting materials and configurations have reduced losses in transmission. Advances in line structures and conductor motion, understanding of flashover characteristics of insulators and air-gaps and electrical performance of lines have resulted in more compact urban transmission lines. (author). 15 refs., 7 tabs., 11 figs

  2. Electrical Subsurface Grounding Analysis

    International Nuclear Information System (INIS)

    J.M. Calle

    2000-01-01

    The purpose and objective of this analysis is to determine the present grounding requirements of the Exploratory Studies Facility (ESF) subsurface electrical system and to verify that the actual grounding system and devices satisfy the requirements

  3. Electric vehicle energy impacts.

    Science.gov (United States)

    2017-05-01

    The objective of this research project was to evaluate the impacts of electric vehicles (EVs) and : renewable wind and solar photovoltaic (PV) power generation on reducing petroleum imports : and greenhouse gas emissions to Hawaii. In 2015, the state...

  4. Electric power generation

    International Nuclear Information System (INIS)

    Pinske, J.D.

    1981-01-01

    Apart from discussing some principles of power industry the present text deals with the different ways of electric power generation. Both the conventional methods of energy conversion in heating and water power stations and the facilities for utilizing regenerative energy sources (sun, wind, ground heat, tidal power) are considered. The script represents the essentials of the lecture of the same name which is offered to the students of the special subject 'electric power engineering' at the Fachhochschule Hamburg. It does not require any special preliminary knowledge except for the general principles of electrical engineering. It is addressing students of electrical engineering who have passed their preliminary examination at technical colleges and universities. Moreover, it shall also be of use for engineers who want to obtain a quick survey of the structure and the operating characteristics of the extremely different technical methods of power generation. (orig.) [de

  5. Home Electrical Safety Checklist

    Science.gov (United States)

    ... Interrupter Protection for Pools, Spas and Hot Tubs Metal Ladders and Electricity Don’t Mix Electrocution Hazard with Do-It-Yourself Repairs of Microwave Ovens Preventing Home Fires: Arc Fault Circuit Interrupters (AFCIs) Power up with ...

  6. Electricity and sustainable development

    International Nuclear Information System (INIS)

    Martin, D.

    2003-11-01

    The sustainable development is a political project. Its purpose is to erase the contradictions between the requirements of Environment and social development. the first article of the law of February 10, 2000 erects a sustainable electricity. For the first time. a law integrates the environmental requirements into the electrical industry. The starting point of this study is in the observation of the effects of this integration in a central sector for the developed countries. electricity is the motive of social development. However, it is carried by a Network. This network results from the confusion between the energy policy and the rules which aim at ensuring the construction and the management of structures of production and transport. Nevertheless, if the energy policy integrates the requirements of the environment, the structures subject them to a dominant social logic which aim is to satisfy an increasing demand for electricity. (author)

  7. The electricity market 2002

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-10-01

    The purpose of the 'Electricity market 2002' publication is to meet the need for generalized and readily accessible information on the conditions on the Nordic market. Iceland is not included in the description. The publication also includes summaries of information from recent years concerning electricity generation and utilization in the Nordic countries, the structure of the electricity market from the players' perspective, trade in electricity in the Nordic countries and in Northern Europe, electricity prices in the Nordic and other countries, and the impact of the electricity sector on the environment. The publication contains data on electricity generation and use during the past years, structure of the electricity market, trade in electricity in the Nordic countries and northern Europe, electricity prices in the Nordic countries and other countries as well as impact of electricity generation system on the environment. The market price of electricity is affected by a number of factors, including fuel prices, availability of water, and the power and energy balances of the various countries. The availability of water in Norway and Sweden has been very good in recent years, which has had a major influence on the price. 1996 was a dry year, which led to a high system price on Nord Pool. The price of electricity then dropped and has remained at a relatively low level up to the year 2001. The price of electricity rose during the spring of 2001 and remained at a higher level also during the summer months. The main reason was that the availability of water was lower than normal in Norway during the early part of the year. This created a higher demand for imported electricity in Norway and caused some apprehension that the year would be dry. The total price of electricity to the end users has not followed the system price development. The total cost of electricity to the end consumers consists of three items, i.e. the price of electricity, the network

  8. Solar electricity for Mali

    Energy Technology Data Exchange (ETDEWEB)

    Naehr, Catrin [SMA Corporate Communication, Niestetal (Germany)

    2013-10-01

    Eight off-grid PV power plants that supply households, schools and smaller businesses in southern Mali villages with electricity not only boost the rural electrification but also the local economy in the crisis-ridden country. (orig.)

  9. Electrical Impedance Tomography Technology

    Data.gov (United States)

    National Aeronautics and Space Administration — The goal for the Electrical Impedance Tomography Technology (EITT) project is to develop a reliable portable, lightweight device providing two-dimensional...

  10. Modernizing Electricity Delivery

    Science.gov (United States)

    Explains how modern grid, or smart grid, investments can enable grid operators to respond faster to changes in grid conditions and allow for two-way communication between utilities and electricity end-users.

  11. Pricing electricity for sustainability : climate change and Canada's electricity sector

    International Nuclear Information System (INIS)

    2010-01-01

    The electricity sector is Canada's largest single source of greenhouse gas (GHG) emissions. This paper discussed electricity and carbon pricing approaches to reducing GHG emissions in the electricity sector. An overview of the links between electricity pricing and climate change was presented, and current and emerging trends in electricity pricing related to encouraging energy conservation were reviewed. Market prices and failures were discussed. Approaches to pricing electricity included an increase in block prices; time-of-use prices; demand-side management and energy efficiency; and carbon pricing in Canada and electricity pricing signals. The study showed that several provincial utilities in Canada are experimenting with market-based pricing approaches for electricity and carbon that may help to reduce GHG emissions over time. Concerns over electricity supply and the negative environmental impacts of electricity production may lead to the full social pricing of electricity in some regions of Canada. 46 refs., 3 tabs., 5 figs.

  12. Swiss electricity statistics 2003

    International Nuclear Information System (INIS)

    2004-01-01

    This publication by the Swiss Federal Office of Energy (SFOE) provides statistical information on electricity supply, production, trading and consumption in Switzerland in 2003. Apart from a general overview of the Swiss electricity supply that includes details on power generation, energy transfer with neighbouring countries and data on prices, average consumption and capital investment, the article also includes graphical representations of electrical energy flows in and out of Switzerland. Tables of data give information on electricity production, import and export for the years 1950 to 2003, the data being supplied for each hydrological year and the summer and winter seasons respectively. The structure of power production in Switzerland is examined in detail and compared with that of foreign countries. Details are given on the development of production capacities and the various means of production together with their respective shares of total production. Further tables and diagrams provide information on power production in various geographical regions and on the management of pumped storage hydro-electricity schemes. A further chapter deals in detail with the consumption of electricity, its growth between 1984 and 2003 and its use in various sectors. A fifth chapter examines electricity consumption, generation, import and export on single, typical days, presenting data in tables and diagrams. The next chapter examines energy transfer with foreign countries and the trading structures involved. The next two chapters cover the future developments in energy exchange and trading with foreign countries and the possibilities of augmenting power generation capacities up to 2010. The final chapter looks at economic considerations involved in the supply of electricity. An annex provides detailed tables of data

  13. Swiss electricity statistics 2003

    International Nuclear Information System (INIS)

    2004-01-01

    This publication by the Swiss Federal Office of Energy (SFOE) for the Swiss Federal Office of Energy (SFOE) provides statistical information on electricity supply, production, trading and consumption in Switzerland in 2003. Apart from a general overview of the Swiss electricity supply that includes details on power generation, energy transfer with neighbouring countries and data on prices, average consumption and capital investment, the publication also includes graphical representations of electrical energy flows in and out of Switzerland. Tables of data give information on electricity production, import and export for the years 1950 to 2003, the data being supplied for each hydrological year and the summer and winter seasons respectively. The structure of power production in Switzerland is examined in detail and compared with that of foreign countries. Details are given on the development of production capacities and the various means of production together with their respective shares of total production. Further tables and diagrams provide information on power production in various geographical regions and on the management of pumped storage hydro-electricity schemes. A further chapter deals in detail with the consumption of electricity, its growth between 1984 and 2003 and its use in various sectors. A fifth chapter examines electricity consumption, generation, import and export on single, typical days, presenting data in tables and diagrams. The next chapter examines energy transfer with foreign countries and the trading structures involved. The next two chapters cover the future developments in energy exchange and trading with foreign countries and the possibilities of augmenting power generation capacities up to 2010. The final chapter looks at economic considerations involved in the supply of electricity. An annex provides detailed tables of data

  14. Swiss electricity statistics 2002

    International Nuclear Information System (INIS)

    2003-01-01

    This publication by the Swiss Federal Office of Energy (SFOE) for the Swiss Federal Office of Energy (SFOE) provides statistical information on electricity supply, production, trading and consumption in Switzerland in 2002. Apart from a general overview of the Swiss electricity supply that includes details on power generation, energy transfer with neighbouring countries and data on prices, average consumption and capital investment, the publication also includes graphical representations of electrical energy flows in and out of Switzerland. Tables of data give information on electricity production, import and export for the years 1950 to 2002, the data being supplied for each hydrological year and the summer and winter seasons respectively. The structure of power production in Switzerland is examined in detail and compared with that of foreign countries. Details are given on the development of production capacities and the various means of production together with their respective shares of total production. Further tables and diagrams provide information on power production in various geographical regions and on the management of pumped storage hydro-electricity schemes. A further chapter deals in detail with the consumption of electricity, its growth between 1984 and 2002 and its use in various sectors. A fifth chapter examines electricity consumption, generation, import and export on single, typical days, presenting data in tables and diagrams. The next chapter examines energy transfer with foreign countries and the trading structures involved. The next two chapters cover the future developments in energy exchange and trading with foreign countries and the possibilities of augmenting power generation capacities up to 2009. The final chapter looks at economic considerations involved in the supply of electricity. An annex provides detailed tables of data

  15. Swiss electricity statistics 2004

    International Nuclear Information System (INIS)

    2005-01-01

    This publication by the Swiss Federal Office of Energy (SFOE) for the Swiss Federal Office of Energy (SFOE) provides statistical information on electricity supply, production, trading and consumption in Switzerland in 2004. Apart from a general overview of the Swiss electricity supply that includes details on power generation, energy transfer with neighbouring countries and data on prices, average consumption and capital investment, the publication also includes graphical representations of electrical energy flows in and out of Switzerland. Tables of data give information on electricity production, import and export for the years 1950 to 2004, the data being supplied for each hydrological year and the summer and winter seasons respectively. The structure of power production in Switzerland is examined in detail and compared with that of foreign countries. Details are given on the development of production capacities and the various means of production together with their respective shares of total production. Further tables and diagrams provide information on power production in various geographical regions and on the management of pumped storage hydro-electricity schemes. A further chapter deals in detail with the consumption of electricity, its growth between 1984 and 2004 and its use in various sectors. A fifth chapter examines electricity consumption, generation, import and export on single, typical days, presenting data in tables and diagrams. The next chapter examines energy transfer with foreign countries and the trading structures involved. The next two chapters cover the future developments in energy exchange and trading with foreign countries and the possibilities of augmenting power generation capacities up to 2010. The final chapter looks at economic considerations involved in the supply of electricity. An annex provides detailed tables of data

  16. Electricity Bill [Part 1

    International Nuclear Information System (INIS)

    Parkinson, C.; Hogg, N.; Salmond, A.

    1988-01-01

    The paper presents the first part of the Parliamentary debate on the second reading of the Electricity Bill, House of Commons, London 1988. The Bill sets out the government's proposals for the restructuring and privatisation of the electricity supply industry throughout Great Britain. Customers and suppliers, choice for the consumer, competition promotion, security of supply, nuclear power stations, and cost, are all discussed. (U.K.)

  17. Privatizing electricity: Pt. 3

    International Nuclear Information System (INIS)

    Bindon, F.J.L.

    1992-01-01

    In these early years of electricity privitization in the United Kingdom, it is impossible to draw any firm conclusions about whether this particular government policy has benefited the country as a whole. This article examines early trends in the economic fortunes of National Power and Power Gen the two non-nuclear utilities and Nuclear Electric, which generate power in England and Wales, as well as Scottish Power, Scottish Hydro and Scottish Nuclear which generate power for Scotland. (UK)

  18. Electricity marketing and retailing

    International Nuclear Information System (INIS)

    Hanlon, C.

    2001-01-01

    ECNG Inc. is a full service provider of independent and objective energy advice and management services to industrial, commercial and institutional end-users of all forms of energy. ECNG manages 10 per cent of the Ontario gas market and expects a 10 per cent share of electricity (14 TWh). ECNG has a balanced portfolio with expertise in both petroleum and electricity sectors. The company has also dealt extensively with retailers, marketers, wholesalers and suppliers on issues regarding deregulation

  19. Swiss electricity statistics 2002

    International Nuclear Information System (INIS)

    Swiss Federal Office of Energy, Berne

    2003-01-01

    This publication by the Swiss Federal Office of Energy (SFOE) provides statistical information on electricity supply, production, trading and consumption in Switzerland in 2002. Apart from a general overview of the Swiss electricity supply that includes details on power generation, energy transfer with neighbouring countries and data on prices, average consumption and capital investment, the article also includes graphical representations of electrical energy flows in and out of Switzerland. Tables of data give information on electricity production, import and export for the years 1950 to 2002, the data being supplied for each hydrological year and the summer and winter seasons respectively. The structure of power production in Switzerland is examined in detail and compared with that of foreign countries. Details are given on the development of production capacities and the various means of production together with their respective shares of total production. Further tables and diagrams provide information on power production in various geographical regions and on the management of pumped storage hydro-electricity schemes. A further chapter deals in detail with the consumption of electricity, its growth between 1984 and 2002 and its use in various sectors. A fifth chapter examines electricity consumption, generation, import and export on single, typical days, presenting data in tables and diagrams. The next chapter examines energy transfer with foreign countries and the trading structures involved. The next two chapters cover the future developments in energy exchange and trading with foreign countries and the possibilities of augmenting power generation capacities up to 2009. The final chapter looks at economic considerations involved in the supply of electricity. An annex provides detailed tables of data

  20. Swiss electricity statistics 2004

    International Nuclear Information System (INIS)

    2005-01-01

    This publication by the Swiss Federal Office of Energy (SFOE) provides statistical information on electricity supply, production, trading and consumption in Switzerland in 2004. Apart from a general overview of the Swiss electricity supply that includes details on power generation, energy transfer with neighbouring countries and data on prices, average consumption and capital investment, the article also includes graphical representations of electrical energy flows in and out of Switzerland. Tables of data give information on electricity production, import and export for the years 1950 to 2004, the data being supplied for each hydrological year and the summer and winter seasons respectively. The structure of power production in Switzerland is examined in detail and compared with that of foreign countries. Details are given on the development of production capacities and the various means of production together with their respective shares of total production. Further tables and diagrams provide information on power production in various geographical regions and on the management of pumped storage hydro-electricity schemes. A further chapter deals in detail with the consumption of electricity, its growth between 1984 and 2004 and its use in various sectors. A fifth chapter examines electricity consumption, generation, import and export on single, typical days, presenting data in tables and diagrams. The next chapter examines energy transfer with foreign countries and the trading structures involved. The next two chapters cover the future developments in energy exchange and trading with foreign countries and the possibilities of augmenting power generation capacities up to 2010. The final chapter looks at economic considerations involved in the supply of electricity. An annex provides detailed tables of data

  1. Privatizing electricity: Pt. 2

    International Nuclear Information System (INIS)

    Bindon, F.J.L.

    1991-01-01

    In February 1988, the Government announced their intention of privatizing the electricity supply industry of England, Wales and Scotland. The Government's proposals were outlined in two White Papers. Cm 322 covered the proposals for England and Wales and Cm 327 the proposals for Scotland. This article deals with the events covering the stages of the privatization process from just before passing of the Electricity Bill in July 1989 to December 1990. (author)

  2. Particle electric dipole moments

    CERN Document Server

    Pendlebury, J M

    2000-01-01

    Measurements of particle electric dipole moments (EDMs) continue to put powerful constraints on theories of T-symmetry and CP-symmetry violation, which form currently one of the most prominent fields in particle physics. EDM measurements have been concentrated on neutral systems such as the neutron and atoms and molecules. These measurements allow one to deduce, in turn, the electric dipole moments of the fundamental fermions, that is, the lighter leptons and quarks and also those of some heavy nuclei.

  3. Electrical and electronic principles

    CERN Document Server

    Knight, SA

    1988-01-01

    Electrical and Electronic Principles, 3 focuses on the principles involved in electrical and electronic circuits, including impedance, inductance, capacitance, and resistance.The book first deals with circuit elements and theorems, D.C. transients, and the series circuits of alternating current. Discussions focus on inductance and resistance in series, resistance and capacitance in series, power factor, impedance, circuit magnification, equation of charge, discharge of a capacitor, transfer of power, and decibels and attenuation. The manuscript then examines the parallel circuits of alternatin

  4. On the electricity shortage, price and electricity theft nexus

    International Nuclear Information System (INIS)

    Jamil, Faisal

    2013-01-01

    Pakistan is facing severe electricity shortfall of its history since 2006. Several measures have been implemented in order to mitigate electricity shortage. The focus has been on raising the installed capacity of electricity generation and transmission. The present policy results in expensive thermal electricity generation mostly using expensive and environmentally hazardous furnace oil and inability of utilities to recover their cost of supply although there is unprecedented rise in electricity tariffs. This study concentrates on the electricity demand and traces the relationship between electricity shortfalls, tariff rate and electricity theft in the background of recent electricity crisis using the data for the period 1985–2010. We employed the Granger causality test through error correction model and out-of-sample causality through variance decomposition method. Empirical evidence shows that electricity theft greatly influences electricity shortfalls through lowering investment and inefficient use of electricity. The study concludes that electricity crisis cannot be handled without combating rampant electricity theft in the country. - Highlights: ► The study investigates relationship among electricity outages, price and electricity theft. ► It employed Johansen approach, ECM and variance decomposition analysis. ► Empirical evidence shows that electricity theft causes outages and rising tariff rates. ► Variance decomposition analysis results are slightly different from ECM

  5. Asia electricity study

    International Nuclear Information System (INIS)

    Priddle, R.

    1997-01-01

    Electricity demand in Asia has grown and continues to grow rapidly. Over 40 per cent of the world's growth in electricity output up to 2010 is expected to come from China and East and South Asia. The need to build the additional production capacity to meet demand is the driving force behind the major structural and institutional changes that are presently transforming the electricity sectors throughout the region. The Asia Electricity Study looks in detail at the current and future role of the electricity sectors in Indonesia, the Philippines and Thailand. It analyses existing and planned electricity policies in areas such as financing regulation, environment and end-use efficiency. To build the region's power infrastructure will require large investments, well beyond what governments or multilateral lending institutions can provide. Consequently, mobilizing private sector participation in the process is vital. Independent Power Producers (IPPs) are being allowed to enter what has, until recently, been a government-dominated field. State-owned utilities are being corporatized and/or privatized to improve their competitiveness. Developing the regulatory environment to match the changes taking place is a key challenge. The significant expansion of generation capacity in Asia will have implications well beyond the region. Changes in energy trade volumes and patterns, caused by the need to obtain fuel for power stations, will have an impact on the energy security of Asia and the world as a whole Similarly, fuel and technology choices will have important consequences for both the regional and global environment. (author)

  6. Essays on electricity markets

    Energy Technology Data Exchange (ETDEWEB)

    Rud, Linda

    2009-07-01

    The report covers several topics of electricity markets: The first essay, 'Selected Topics on Early Electricity Market Design in Norway' studies market design issues in establishing the market-based Norwegian electricity market. Essays 2-4 focus on issues of network congestion: 'Capacity Charges: A Price Adjustment Process for Managing Congestion in Electricity Transmission Networks' presents the capacity charge approach for managing transmission constraints in electricity networks. 'Understanding the Stochastics of Nodal Prices: Price Processes in a Constrained Network' seeks a further understanding of stochastic nodal prices processes. 'Investment Evaluation in a Constrained Electricity Network with Stochastic Nodal Price Processes' studies how the interaction of the competitive market and the capacitated network affects the evaluation of investments under uncertainty, and points out potential pitfalls of evaluation. In the last essay, 'A Newsboy Model Perspective on the Power Market: The Case of a Wind Power Producer' we discuss aspects of optimal bidding for a wind power producer. (Author)

  7. Electricity and magnetism

    CERN Document Server

    Robertson, William C

    2005-01-01

    Shocked by static? Mixed up about magnets? Curious about currents? This book will help you get beyond memorizing electricity-related formulas, rules, and procedures so you can understand the topic at a deep level deep enough to teach it with confidence and comfort. By covering the basics of static electricity, current electricity, and magnetism, the book develops a scientific model showing that electricity and magnetism are really the same phenomenon in different forms. A bonus feature: access to interactive software that you can download from the NSTA Web site. The software will help you investigate electrical circuits from simple to complex without having to buy a lot of expensive materials (or risking electrocution!). Electricity and Magnetism is the fifth title in the award-winning NSTA Press Stop Faking It! Series. As author Bill Robertson writes, The book you have in your hands is not a textbook. It is, however, designed to help you get science at a level you never thought possible, and also to bring yo...

  8. The electric vehicle

    International Nuclear Information System (INIS)

    Sanchez duran, R.

    2010-01-01

    The decarbonization of transport is a key element in both energy and environmental European policies as well as one of the levers that will help us achieve the goals of improving energy efficiency, reducing CO 2 emissions and energy dependence. The use of electricity compared to other low-carbon fuels such as bio fuels and hydrogen has the advantage of its existing infrastructure (power generation plants, transmission and distribution networks), being only necessary to developed recharging infrastructures. We emphasize the role of electricity networks and their evolution, which will enable to manage demand and maximise the potential of renewable energies. The idea of an electric vehicle is not a recent one but dates back to the beginning of the last century, when first units appeared. Unfortunately, technological barriers were too high at the time to let them succeed. Namely those barriers limited the range of the electric vehicle due to problems with battery recharges. Nowadays, those difficulties have almost been solved and we can state that institutional support and coordination among all actors involved have made the electric vehicle a plausible reality. While the technological improvements needed for the electric vehicle to become cost competitive are carried out, the plug-in hybrid vehicle represents the intermediate step to reach a total decarbonization of transport. Endesa is committed to this revolution in transport mobility and believes that now is the right time to focus our efforts on it. Our goal is to contribute to a more balanced and sustainable world in the near future. (Author)

  9. How does Germany's green energy policy affect electricity market volatility? An application of conditional autoregressive range models

    International Nuclear Information System (INIS)

    Auer, Benjamin R.

    2016-01-01

    Based on a dynamic model for the high/low range of electricity prices, this article analyses the effects of Germany's green energy policy on the volatility of the electricity market. Using European Energy Exchange data from 2000 to 2015, we find rather high volatility in the years 2000–2009 but also that the weekly price range has significantly declined in the period following the year 2009. This period is characterised by active regulation under the Energy Industry Law (EnWG), the EU Emissions Trading Directive (ETD) and the Renewable Energy Law (EEG). In contrast to the preceding period, price jumps are smaller and less frequent (especially for day-time hours), implying that current policy measures are effective in promoting renewable energies while simultaneously upholding electricity market stability. This is because the regulations strive towards a more and more flexible and market-oriented structure which allows better integration of renewable energies and supports an efficient alignment of renewable electricity supply with demand. - Highlights: • We estimate a CARR model for German electricity price data. • We augment the model by dummies capturing important regulations. • We find a significant decline in the price range after the year 2009. • This implies effective price stabilisation by German energy policy.

  10. Can el Hierro be 100% electric-renewable?

    International Nuclear Information System (INIS)

    Flocard, Hubert

    2016-01-01

    This summer, the media have abundantly reported that the el-Hierro island in the Canaries could now count on a 100 % renewable electric mix. As a matter of fact, these reports were based on only two hours during which the Gorona del Viento (GdV) installation managed to reach the objectives announced in the project document. Full of enthusiasm, Segolene Royal, the French minister of environment and energy, rewarded the project on behalf of the 'Syndicat des energies Renouvelables' What is the situation today for this installation inaugurated in June 2014? a considerable investment, leading to a complex system with more than 34 MW of installed production power (diesel, wind and hydraulic turbines, each for about one third) when the peak electric demand is only 7.6 MW that is a factor four less. The reality of the performances after six months of effective exploitation: the renewable fraction for the three most favourable months, July to September, has been 42 %. For the half year, the figure is even more disappointing with only 30 % renewables. The reasons behind these very modest performances with respect to the announced goal, which, moreover for the year 2015, lead to a considerable cost of the renewable MWh which is going to cost four times more than the MWh produced by the diesel plant and a cost of the avoided CO 2 exceeding 1000 Euro/ton? As shown in this document, they are first the limited wind resource, which according to data could not have allowed a renewable fraction larger than 50 % and second, the nature of the contract signed by the Spanish state which does not encourage GdV to strive for the optimal environmental performances. To summarize: unrealistic objectives, deplorable governance and a technical semi-failure very costly for the Spanish citizen. (author)

  11. 体育强国进程中民间体育组织的培育与发展研究%On the Cultivation and Development of Folk Sports Organizations in the Process of Striving for a Sports Power

    Institute of Scientific and Technical Information of China (English)

    魏丽艳

    2015-01-01

    After the 29th Olympic Games,our country put forward the objective to strive for a sports power in the new era.Mass sports and competitive sports should be developed harmoniously in order to fulfill this strategic target.Organizations of folk sports are the footstones to improve work of mass sports.Based on methods of document,logical analysis,etc.,the essay analyzes the important roles of mass sports organizations and current difficulties in the process of building a sports power.To achieve the goal,the essay suggests that the government should work hard to change its ideas to cultivate and develop mass sports organizations.At the same time,mass sports organizations should pay more atten-tion on self discipline,increase and perfect its management level continually.They should adopt the strategies of win win cooperation to consolidate and strengthen the partnership relationship.In a word, we wish it can provide some benefits in the process of turning our country into a sports power.%29届奥运会后,国家提出了向体育强国迈进的新时期体育工作目标,群众体育与竞技体育协调发展是实现这个战略目标的重要保障。民间体育组织是提高群众体育工作的基石。运用文献资料、逻辑分析等研究方法,分析了民间体育组织在建设体育强国进程中的重要作用及面临的现实困境,提出政府要转变观念,着力培育和发展民间体育组织;民间体育组织要强化自律,不断提高和完善自身管理水平;合作共赢,持续巩固和夯实合作伙伴关系等策略,以加快体育强国进程。

  12. The search for electric dipole moments of light ions in storage rings

    International Nuclear Information System (INIS)

    Rathmann, Frank; Saleev, Artem; Nikolaev, N N

    2013-01-01

    The Standard Model (SM) of Particle Physics is not capable of accounting for the apparent matter-antimatter asymmetry of our universe. Physics beyond the SM is required and is searched for by (i) employing highest energies (e.g., at LHC), and (ii) striving for ultimate precision and sensitivity (e.g., in the search for electric dipole moments (EDMs)). Permanent EDMs of particles violate both time reversal (T) and parity (P) invariance, and are via the CPT-theorem also CP-violating. Finding an EDM would be a strong indication for physics beyond the SM, and reducing upper limits further provides crucial tests for any corresponding theoretical model, e.g., SUSY. Direct searches for proton and deuteron EDMs bear the potential to reach sensitivities beyond 10 −29 e·cm. For an all-electric proton storage ring, this goal is pursued by the US-based srEDM collaboration [1], while the newly founded Jülich-based JEDI collaboration [2] is pursuing an approach using a combined electric-magnetic lattice, which shall provide access to the EDMs of protons, deuterons, and 3 He ions in the same machine. In addition, JEDI has recently proposed making a direct measurement of the proton and/or deuteron EDM at COSY using resonant techniques involving Wien filters

  13. Electrical model of Olkiluoto

    Energy Technology Data Exchange (ETDEWEB)

    Paananen, M.; Lehtonen, T.; Korhonen, K. (Geological Survey of Finland, Espoo (FI))

    2007-05-15

    The goal of this work is to construct a composite electrical model of Olkiluoto, focussing on integration of four separate geophysical methods: mise-a-la-masse (MAM), SAMPO EM soundings, Slingram (HLEM) and single-hole electrical soundings. The electrical structure of Olkiluoto is rather complex, dominated by mineral electrical conductors such as sulphide minerals and graphite. The basic idea of this work is the fact that the sulphide-rich zones and fracturing appear to coincide frequently. Accordingly, knowing the geometry of the major electric conductors would facilitate the interpretation of brittle deformation zones. The work consists of three separate phases: method-specific interpretation, integration and block modelling. In the single-hole interpretation, locations of electric conductors (resistivity < 1000 ohmm), based on long normal survey have been determined in 42 drillholes. Since MAM survey does not cover all the conductive sections and drillholes and SAMPO EM has its own limitations in sensitivity and resolution, a proportion of the conductive sections have been combined between the drillholes using only the single-hole data and the geological idea of features dipping gently to SE - S. The MAM survey has been done in numerous drillholes in order to find galvanic connections between the drillholes. Based on MAM, geometry of numerous electric conductors has been determined. Generally the results indicate continuous, gently dipping semiplanar features intersected by several drillholes. The Slingram survey and interpretation have been done on the ground surface to map electric conductors located at shallow depths (some tens of meters at maximum). A number of conductive zones have been delineated, trending mainly from ENE to WSW. The conductors have also been classified according to their in-phase/quadrature-ratio, and in some cases, also numerical modelling has been done. The SAMPO EM soundings and interpretations have been done to map subsurface electric

  14. Electrical model of Olkiluoto

    International Nuclear Information System (INIS)

    Paananen, M.; Lehtonen, T.; Korhonen, K.

    2007-05-01

    The goal of this work is to construct a composite electrical model of Olkiluoto, focussing on integration of four separate geophysical methods: mise-a-la-masse (MAM), SAMPO EM soundings, Slingram (HLEM) and single-hole electrical soundings. The electrical structure of Olkiluoto is rather complex, dominated by mineral electrical conductors such as sulphide minerals and graphite. The basic idea of this work is the fact that the sulphide-rich zones and fracturing appear to coincide frequently. Accordingly, knowing the geometry of the major electric conductors would facilitate the interpretation of brittle deformation zones. The work consists of three separate phases: method-specific interpretation, integration and block modelling. In the single-hole interpretation, locations of electric conductors (resistivity < 1000 ohmm), based on long normal survey have been determined in 42 drillholes. Since MAM survey does not cover all the conductive sections and drillholes and SAMPO EM has its own limitations in sensitivity and resolution, a proportion of the conductive sections have been combined between the drillholes using only the single-hole data and the geological idea of features dipping gently to SE - S. The MAM survey has been done in numerous drillholes in order to find galvanic connections between the drillholes. Based on MAM, geometry of numerous electric conductors has been determined. Generally the results indicate continuous, gently dipping semiplanar features intersected by several drillholes. The Slingram survey and interpretation have been done on the ground surface to map electric conductors located at shallow depths (some tens of meters at maximum). A number of conductive zones have been delineated, trending mainly from ENE to WSW. The conductors have also been classified according to their in-phase/quadrature-ratio, and in some cases, also numerical modelling has been done. The SAMPO EM soundings and interpretations have been done to map subsurface electric

  15. Cryogenic Electric Motor Tested

    Science.gov (United States)

    Brown, Gerald V.

    2004-01-01

    Technology for pollution-free "electric flight" is being evaluated in a number of NASA Glenn Research Center programs. One approach is to drive propulsive fans or propellers with electric motors powered by fuel cells running on hydrogen. For large transport aircraft, conventional electric motors are far too heavy to be feasible. However, since hydrogen fuel would almost surely be carried as liquid, a propulsive electric motor could be cooled to near liquid hydrogen temperature (-423 F) by using the fuel for cooling before it goes to the fuel cells. Motor windings could be either superconducting or high purity normal copper or aluminum. The electrical resistance of pure metals can drop to 1/100th or less of their room-temperature resistance at liquid hydrogen temperature. In either case, super or normal, much higher current density is possible in motor windings. This leads to more compact motors that are projected to produce 20 hp/lb or more in large sizes, in comparison to on the order of 2 hp/lb for large conventional motors. High power density is the major goal. To support cryogenic motor development, we have designed and built in-house a small motor (7-in. outside diameter) for operation in liquid nitrogen.

  16. Hybrid Turbine Electric Vehicle

    Science.gov (United States)

    Viterna, Larry A.

    1997-01-01

    Hybrid electric power trains may revolutionize today's ground passenger vehicles by significantly improving fuel economy and decreasing emissions. The NASA Lewis Research Center is working with industry, universities, and Government to develop and demonstrate a hybrid electric vehicle. Our partners include Bowling Green State University, the Cleveland Regional Transit Authority, Lincoln Electric Motor Division, the State of Ohio's Department of Development, and Teledyne Ryan Aeronautical. The vehicle will be a heavy class urban transit bus offering double the fuel economy of today's buses and emissions that are reduced to 1/10th of the Environmental Protection Agency's standards. At the heart of the vehicle's drive train is a natural-gas-fueled engine. Initially, a small automotive engine will be tested as a baseline. This will be followed by the introduction of an advanced gas turbine developed from an aircraft jet engine. The engine turns a high-speed generator, producing electricity. Power from both the generator and an onboard energy storage system is then provided to a variable-speed electric motor attached to the rear drive axle. An intelligent power-control system determines the most efficient operation of the engine and energy storage system.

  17. Swiss electrical power association

    International Nuclear Information System (INIS)

    1983-01-01

    Milestones of electrical power development in Switzerland during 1982 are quoted. An energy balance is shown for the utilisation of 864,630 terajoules of primary energy. This is related to global data on per capita power consumption. In the electricity generation section, annual load factors are given for the four nuclear stations. A brief review is made of hydro potential and monthly export/import figures for power to other countries (mostly export, especially in summer). Total electrical power output grew about 1.3% in the last year. Recent transmission line developments are noted, mostly 2x380kV, and including a link with Austria. In the financial section, consumer price indices are quoted for liquid and solid fuel, gas and electricity since 1966. Under administration, details are listed of the main and about 18 supporting Committees and working groups with special functions (e.g. tariffs, electrical vehicles). Public relations have included nuclear power press conferences, a mobile video unit, information leaflets for the media and a teaching seminar. (G.C.)

  18. Mexican renewable electricity law

    Energy Technology Data Exchange (ETDEWEB)

    Ruiz-Mendoza, B.J.; Sheinbaum-Pardo, C. [Institute of Engineering of the National Autonomous University of Mexico, Circuito Exterior s/n, Edificio 12 Bernardo Quintana, Piso 3, Cubiculo 319, Ciudad Universitaria, Delegacion Coyoacan, CP 04510, Mexico D.F. (Mexico)

    2010-03-15

    Two renewable electricity bills have been proposed in Congress since 2005 in Mexico. The first one was rejected by the Senate and the second one was approved by both the House of Representatives and the Senate in October 2008. Our objective is to explain the nature of both bills and to analyze each of them bearing in mind the Mexican electricity sector management scheme. In the Mexican electricity sector single-buyer scheme, the state-owned companies (Comision Federal de Electricidad and Luz y Fuerza del Centro) are responsible of the public services and the private sector generates electricity under six modalities: self-supply, cogeneration, independent production, small production, export, and import, which are not considered a public service. This scheme has caused controversies related to the constitutionality of the 1992 Power Public Services Law that allowed this scheme to be implemented. Both bills, the rejected one and the approved one, were formulated and based on that controversial law and their objectives are linked precisely more to the controversial issues than to the promotion of renewable electricity technologies; consequently, the gap among environmental, economic and social issues related with sustainability notion is wider. (author)

  19. Fully electric waste collection

    CERN Multimedia

    Anaïs Schaeffer

    2015-01-01

    Since 15 June, Transvoirie, which provides waste collection services throughout French-speaking Switzerland, has been using a fully electric lorry for its collections on the CERN site – a first for the region!   Featuring a motor powered by electric batteries that charge up when the brakes are used, the new lorry that roams the CERN site is as green as can be. And it’s not only the motor that’s electric: its waste compactor and lifting mechanism are also electrically powered*, making it the first 100% electric waste collection vehicle in French-speaking Switzerland. Considering that a total of 15.5 tonnes of household waste and paper/cardboard are collected each week from the Meyrin and Prévessin sites, the benefits for the environment are clear. This improvement comes as part of CERN’s contract with Transvoirie, which stipulates that the firm must propose ways of becoming more environmentally friendly (at no extra cost to CERN). *The was...

  20. Electrical distribution system management

    International Nuclear Information System (INIS)

    Hajos, L.; Mortarulo, M.; Chang, K.; Sparks, T.

    1990-01-01

    This paper reports that maintenance of electrical system data is essential to the operation, maintenance, and modification of a nuclear station. Load and equipment changes affect equipment sizing, available short-circuit currents and protection coordination. System parameters must be maintained in a controlled manner to enable evaluation of proposed modifications and provide adequate verification and traceability. For this purpose, Public Service Electric and Gas Company has implemented a Verified and Validated Electric Distribution System Management (EDSM) program at the Hope Creek and Salem Nuclear Power Stations. EDSM program integrates computerized configuration management of electrical systems with calculational software the Technical Standard procedures. The software platform is PC-based. The Database Manager and Calculational programs have been linked together through a user friendly menu system. The database management nodule enable s assembly and maintenance of databases for individual loads, buses, and branches within the electrical systems with system access and approval controlled through electronic security incorporated within the database manger. Reports drawn from the database serve as the as-built and/or as-designed record of the system configurations. This module also creates input data files of network parameters in a format readable by the calculational modules. Calculations modules provide load flow, voltage drop, motor starting, and short-circuit analyses, as well as dynamic analyses of bus transfers