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Sample records for personal exposures effects

  1. Effectiveness of a personalized ventilation system in reducing personal exposure against directly released simulated cough droplets

    DEFF Research Database (Denmark)

    Pantelic, J.; Tham, K. W.; Licina, Dusan

    2015-01-01

    manikin at distances between 1 and 4m. Cough droplet concentration was measured with an aerosol spectrometer in the breathing zone of a thermal manikin. Particle image velocimetry was used to characterize the velocity field in the breathing zone. Desktop personalized ventilation substantially reduced......The inhalation intake fraction was used as an indicator to compare effects of desktop personalized ventilation and mixing ventilation on personal exposure to directly released simulated cough droplets. A cough machine was used to simulate cough release from the front, back, and side of a thermal...

  2. Effectiveness of a personalized ventilation system in reducing personal exposure against directly released simulated cough droplets.

    Science.gov (United States)

    Pantelic, J; Tham, K W; Licina, D

    2015-12-01

    The inhalation intake fraction was used as an indicator to compare effects of desktop personalized ventilation and mixing ventilation on personal exposure to directly released simulated cough droplets. A cough machine was used to simulate cough release from the front, back, and side of a thermal manikin at distances between 1 and 4 m. Cough droplet concentration was measured with an aerosol spectrometer in the breathing zone of a thermal manikin. Particle image velocimetry was used to characterize the velocity field in the breathing zone. Desktop personalized ventilation substantially reduced the inhalation intake fraction compared to mixing ventilation for all investigated distances and orientations of the cough release. The results point out that the orientation between the cough source and the breathing zone of the exposed occupant is an important factor that substantially influences exposure. Exposure to cough droplets was reduced with increasing distance between cough source and exposed occupant. The results from this study show that an advanced air distribution system such as personalized ventilation reduces exposure to cough-released droplets better than commonly applied overhead mixing ventilation. This work can inform HVAC engineers about different aspects of air distribution systems’ performance and can serve as an aid in making critical design decisions. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  3. Personal exposure control system

    International Nuclear Information System (INIS)

    Tanabe, Ken-ichi; Akashi, Michio

    1994-01-01

    Nuclear power stations are under strict radiation control. Exposure control for nuclear workers is the most important operation, and so carefully thought out measures are taken. This paper introduces Fuji Electric's personal exposure control system that meets strict exposure control and rationalizes control operations. The system has a merit that it can provide required information in an optimum form using the interconnection of a super minicomputer and exposure control facilities and realizes sophisticated exposure control operations. (author)

  4. Effects of personal air pollution exposure on asthma symptoms, lung function and airway inflammation.

    Science.gov (United States)

    Chambers, L; Finch, J; Edwards, K; Jeanjean, A; Leigh, R; Gonem, S

    2018-03-11

    There is evidence that air pollution increases the risk of asthma hospitalizations and healthcare utilization, but the effects on day-to-day asthma control are not fully understood. We undertook a prospective single-centre panel study to test the hypothesis that personal air pollution exposure is associated with asthma symptoms, lung function and airway inflammation. Thirty-two patients with a clinical diagnosis of asthma were provided with a personal air pollution monitor (Cairclip NO 2 /O 3 ) which was kept on or around their person throughout the 12-week follow-up period. Ambient levels of NO 2 and particulate matter were modelled based upon satellite imaging data. Directly measured ozone, NO 2 and particulate matter levels were obtained from a monitoring station in central Leicester. Participants made daily electronic records of asthma symptoms, peak expiratory flow and exhaled nitric oxide. Spirometry and asthma symptom questionnaires were completed at fortnightly study visits. Data were analysed using linear mixed effects models and cross-correlation. Cairclip exposure data were of good quality with clear evidence of diurnal variability and a missing data rate of approximately 20%. We were unable to detect consistent relationships between personal air pollution exposure and clinical outcomes in the group as a whole. In an exploratory subgroup analysis, total oxidant exposure was associated with increased daytime symptoms in women but not men. We did not find compelling evidence that air pollution exposure impacts on day-to-day clinical control in an unselected asthma population, but further studies are required in larger populations with higher exposure levels. Women may be more susceptible than men to the effects of air pollution, an observation which requires confirmation in future studies. © 2018 John Wiley & Sons Ltd.

  5. Investigating the association of cardiovascular effects with personal exposure to particle components and sources

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Chang-fu, E-mail: changfu@ntu.edu.tw [Department of Public Health, National Taiwan University, Taipei 100, Taiwan (China); Institute of Environmental Health, National Taiwan University, Taipei 100, Taiwan (China); Institute of Occupational Medicine and Industrial Hygiene, Taipei 100, Taiwan (China); Li, Ya-Ru; Kuo, I-Chun [Institute of Environmental Health, National Taiwan University, Taipei 100, Taiwan (China); Hsu, Shih-Chieh [Research Center for Environmental Changes, Academia Sinica, Taipei 115, Taiwan (China); Lin, Lian-Yu; Su, Ta-Chen [Department of Internal Medicine, National Taiwan University Hospital, Taipei 100, Taiwan (China)

    2012-08-01

    Background: Few studies included information on components and sources when exploring the cardiovascular health effects from personal exposure to particulate matters (PM). We previously reported that exposure to PM between 1.0 and 2.5 {mu}m (PM{sub 2.5-1}) was associated with increased cardio-ankle vascular index (CAVI, an arterial stiffness index), while exposure to PM smaller than 0.25 {mu}m (PM{sub 0.25}) decreased the heart rate variability (HRV) indices. The purpose of this study was to investigate the association between PM elements and cardiovascular health effects and identify responsible sources. Methods: In a panel study of seventeen mail carriers, the subjects were followed for 5-6 days while delivering mail outdoors. Personal filter samples of PM{sub 2.5-1} and PM{sub 0.25} were analyzed for their elemental concentrations. The source-specific exposures were further estimated by using absolute principal factor analysis. We analyzed the component- and source-specific health effects on HRV indices and CAVI using mixed models. Results: Several elements in PM{sub 2.5-1} (e.g., cadmium and strontium) were associated with the CAVI. Subsequent analyses showed that an interquartile range increase in exposure to PM from regional sources was significantly associated with a 3.28% increase in CAVI (95% confidence interval (CI), 1.47%-5.13%). This significant effect remained (3.35%, CI: 1.62%-5.11%) after controlling for the ozone exposures. For exposures to PM{sub 0.25}, manganese, calcium, nickel, and chromium were associated with the CAVI and/or the HRV indices. Conclusions: Our study suggests that PM{sub 2.5-1} and PM{sub 0.25} components may be associated with different cardiovascular effects. Health risks from exposure to PM from sources other than vehicle exhaust should not be underappreciated. - Highlights: Black-Right-Pointing-Pointer Increased arterial stiffness was related to the components in particles between 1.0 and 2.5 {mu}m. Black

  6. Experimental effects of exposure to pornography: the moderating effect of personality and mediating effect of sexual arousal.

    Science.gov (United States)

    Hald, Gert Martin; Malamuth, Neil N

    2015-01-01

    Using a randomly selected community sample of 200 Danish young adult men and women in a randomized experimental design, the study investigated the effects of a personality trait (agreeableness), past pornography consumption, and experimental exposure to non-violent pornography on attitudes supporting violence against women (ASV). We found that lower levels of agreeableness and higher levels of past pornography consumption significantly predicted ASV. In addition, experimental exposure to pornography increased ASV but only among men low in agreeableness. This relationship was found to be significantly mediated by sexual arousal with sexual arousal referring to the subjective assessment of feeling sexually excited, ready for sexual activities, and/or bodily sensations associated with being sexually aroused. In underscoring the importance of individual differences, the results supported the hierarchical confluence model of sexual aggression and the media literature on affective engagement and priming effects.

  7. Personal exposure to ultrafine particles.

    Science.gov (United States)

    Wallace, Lance; Ott, Wayne

    2011-01-01

    Personal exposure to ultrafine particles (UFP) can occur while people are cooking, driving, smoking, operating small appliances such as hair dryers, or eating out in restaurants. These exposures can often be higher than outdoor concentrations. For 3 years, portable monitors were employed in homes, cars, and restaurants. More than 300 measurement periods in several homes were documented, along with 25 h of driving two cars, and 22 visits to restaurants. Cooking on gas or electric stoves and electric toaster ovens was a major source of UFP, with peak personal exposures often exceeding 100,000 particles/cm³ and estimated emission rates in the neighborhood of 10¹² particles/min. Other common sources of high UFP exposures were cigarettes, a vented gas clothes dryer, an air popcorn popper, candles, an electric mixer, a toaster, a hair dryer, a curling iron, and a steam iron. Relatively low indoor UFP emissions were noted for a fireplace, several space heaters, and a laser printer. Driving resulted in moderate exposures averaging about 30,000 particles/cm³ in each of two cars driven on 17 trips on major highways on the East and West Coasts. Most of the restaurants visited maintained consistently high levels of 50,000-200,000 particles/cm³ for the entire length of the meal. The indoor/outdoor ratios of size-resolved UFP were much lower than for PM₂.₅ or PM₁₀, suggesting that outdoor UFP have difficulty in penetrating a home. This in turn implies that outdoor concentrations of UFP have only a moderate effect on personal exposures if indoor sources are present. A time-weighted scenario suggests that for typical suburban nonsmoker lifestyles, indoor sources provide about 47% and outdoor sources about 36% of total daily UFP exposure and in-vehicle exposures add the remainder (17%). However, the effect of one smoker in the home results in an overwhelming increase in the importance of indoor sources (77% of the total).

  8. Genotoxic effects of daily personal exposure to particle mass and number concentrations on buccal cells

    Science.gov (United States)

    de Almeida, Daniela S.; da Costa, Silvano César; Ribeiro, Marcos; Moreira, Camila A. B.; Beal, Alexandra; Squizzato, Rafaela; Rudke, Anderson Paulo; Rafee, Sameh Adib Abou; Martins, Jorge A.; Palioto, Graciana Freitas; Kumar, Prashant; Martins, Leila D.

    2018-03-01

    The aim of this study is to assess personal exposure to Particle Number Concentrations (PNC) in four size ranges between 0.3 and 10 μm, and particulate matter (PM1; PM2.5; PM4; PM10) in order to evaluate possible genotoxic effects through a comet assay in buccal cells. A convenience cohort of 30 individuals from a Brazilian medium-sized city was selected. These individuals aged between 20 and 61 and worked in typical job categories (i.e., administrative, commerce, education, general services and transport). They were recruited to perform personal exposure measurements during their typical daily routine activities, totaling 240 h of sampling. The 8-h average mass concentrations in air for volunteers ranged from 2.4 to 31.8 μg m-3 for PM1, 4.2-45.1 μg m-3 for PM2.5, 7.9-66.1 μg m-3 for PM4 and from 23.1 to 131.7 μg m-3 for PM10. The highest PNC variation was found for 0.3-0.5 range, between 14 and 181 particles cm-3, 1 to 14 particles cm-3 for the 0.5-1.0 range, 0.2 to 2 particles cm-3 for the 1.0-2.5 range, and 0.06 to 0.7 particles cm-3 for the 2.5-10 range. Volunteers in the 'education' category experienced the lowest inhaled dose of PM2.5, as opposed to those involved in 'commercial' activities with the highest doses for PM10 (1.63 μg kg-1 h-1) and PM2.5 (0.61 μg kg-1 h-1). The predominant cause for these high doses was associated with the proximity of the workplace to the street and vehicle traffic. The comet assay performed in buccal cells indicated that the volunteers in 'commerce' category experienced the highest damage to their DeoxyriboNucleic Acid (DNA) compared with the control category (i.e. 'education'). These results indicate the variability in personal exposure of the volunteers in different groups, and the potential damage to DNA was much higher for those spending time in close proximity to the vehicle sources (e.g. commercial services) leading to exposure to a higher fraction of fine particles. This study builds understanding on the exposure

  9. Effects of Video Exposure to Cluttering on Undergraduate Students' Perceptions of a Person Who Clutters

    Science.gov (United States)

    Farrell, Lindsey M.; Blanchet, Paul G.; Tillery, Kim L.

    2015-01-01

    Background: Previous research suggests a negative stereotype toward people with fluency disorders (i.e. stuttering and/or cluttering), although recent findings suggest that exposure to an actual person who stutters (e.g. a live or video presentation) leads to more positive perceptions of some personality traits. However, there is a paucity of…

  10. A principal components analysis of the factors effecting personal exposure to air pollution in urban commuters in Dublin, Ireland.

    Science.gov (United States)

    McNabola, Aonghus; Broderick, Brian M; Gill, Laurence W

    2009-10-01

    Principal component analysis was used to examine air pollution personal exposure data of four urban commuter transport modes for their interrelationships between pollutants and relationships with traffic and meteorological data. Air quality samples of PM2.5 and VOCs were recorded during peak traffic congestion for the car, bus, cyclist and pedestrian between January 2005 and June 2006 on a busy route in Dublin, Ireland. In total, 200 personal exposure samples were recorded each comprising 17 variables describing the personal exposure concentrations, meteorological conditions and traffic conditions. The data reduction technique, principal component analysis (PCA), was used to create weighted linear combinations of the data and these were subsequently examined for interrelationships between the many variables recorded. The results of the PCA found that personal exposure concentrations in non-motorised forms of transport were influenced to a higher degree by wind speed, whereas personal exposure concentrations in motorised forms of transport were influenced to a higher degree by traffic congestion. The findings of the investigation show that the most effective mechanisms of personal exposure reduction differ between motorised and non-motorised modes of commuter transport.

  11. Personal Chemical Exposure informatics

    Science.gov (United States)

    Chemical Exposure science is the study of human contact with chemicals (from manufacturing facilities, everyday products, waste) occurring in their environments and advances knowledge of the mechanisms and dynamics of events that cause or prevent adverse health outcomes. (adapted...

  12. Occupational radiation exposure in Germany: many monitored persons = high exposure?

    International Nuclear Information System (INIS)

    Nitschke, J.

    1996-01-01

    Natural radiation affects the entire population in Germany, and most of Germany's inhabitants are exposed to medical radiation in their lifetime. Occupational radiation exposure, however, is a kind of exposure affecting only a limited and well-defined group of the population, and this radiation exposure has been recorded and monitored as precisely as technically possible ever since the radiation protection laws made occupational radiation exposure monitoring a mandatory obligation. Official personal dosimetry applying passive dosemeters in fact does not offer direct protection against the effects of ionizing radiation, as dosemeter read-out and dose calculation is a post-exposure process. But it nevertheless is a rewarding monitoring duty under radiation protection law, as is shown by the radiation exposure statistics accumulated over decades: in spite of the number of monitored persons having been increasing over the years, the total exposure did not, due to the corresponding improvements in occupational radiation protection. (orig.) [de

  13. Effectiveness of personal protective equipment: Relevance of dermal and inhalation exposure to chlorpyrifos among pest control operators

    NARCIS (Netherlands)

    Jagt, K. van der; Tielemans, E.; Links, I.; Brouwer, D.; Hemmen, J. van

    2004-01-01

    This study assessed the effectiveness of a custom fit personal protective equipment (PPE) program aimed at reducing occupational exposure to pesticides. The intervention study was carried out on 15 pest control operators (PCOs) during mixing/loading and application of chlorpyrifos. Each worker was

  14. Determination of silver in personal care nanoproducts and effects on dermal exposure

    Energy Technology Data Exchange (ETDEWEB)

    Wasukan, Nootcharin [National Science and Technology Development Agency (NSTDA), National Nanotechnology Center (Thailand); Srisung, Sujittra, E-mail: sujittras@g.swu.ac.th [Srinakharinwirot University, Department of Chemistry, Faculty of Science (Thailand); Kulthong, Kornphimol; Boonrungsiman, Suwimon; Maniratanachote, Rawiwan, E-mail: rawiwan@nanotec.or.th [National Science and Technology Development Agency (NSTDA), National Nanotechnology Center (Thailand)

    2015-11-15

    Silver (Ag) is one of the widely used nanomaterials in cosmetics, personal care, and household products. This research aimed to investigate the Ag concentration contained in 20 commercial nanoproducts using a simple and reliable procedure. The exposure and adverse effects of a single topical application of Ag on the skin were also evaluated. Herein, we demonstrated that the technique of wet acid digestion, extraction and detection of Ag with graphite furnace absorption spectrometry were effective for any and all nanoproduct matrices. The Ag morphology was characterized by scanning and transmission electron microscopy equipped with energy-dispersive x-ray spectroscopy. Penetration of Ag was evaluated using a polyethersulfone (PES) membrane through a Franz cell and reconstructed human epidermis (RhE) tissue. A skin irritation test was performed on RhE, an acceptable in vitro model which was in compliance with OECD test guideline 439. The results showed that the initial Ag concentration in the tested nanoproducts ranged between 0.0058 and 94 µg/g. However, particulate Ag was only found in two products, both of a liquid formulation. Silver penetration through a PES membrane (0.12–53 % by weight) was weakly correlated with the initial Ag concentration in each sample, but more so to the product formulation. The liquid products demonstrated the highest percent of average Ag penetration, followed by the semi-solid and solid formulations, respectively. In contrast, neither any Ag diffusion from these products into the RhE tissue nor any irritation or toxicity was detected. This study suggests a screening method to evaluate the Ag level in products and their potential adverse effects on the skin that could be incorporated as a part of risk assessment for nanotechnology products.

  15. Determination of silver in personal care nanoproducts and effects on dermal exposure

    International Nuclear Information System (INIS)

    Wasukan, Nootcharin; Srisung, Sujittra; Kulthong, Kornphimol; Boonrungsiman, Suwimon; Maniratanachote, Rawiwan

    2015-01-01

    Silver (Ag) is one of the widely used nanomaterials in cosmetics, personal care, and household products. This research aimed to investigate the Ag concentration contained in 20 commercial nanoproducts using a simple and reliable procedure. The exposure and adverse effects of a single topical application of Ag on the skin were also evaluated. Herein, we demonstrated that the technique of wet acid digestion, extraction and detection of Ag with graphite furnace absorption spectrometry were effective for any and all nanoproduct matrices. The Ag morphology was characterized by scanning and transmission electron microscopy equipped with energy-dispersive x-ray spectroscopy. Penetration of Ag was evaluated using a polyethersulfone (PES) membrane through a Franz cell and reconstructed human epidermis (RhE) tissue. A skin irritation test was performed on RhE, an acceptable in vitro model which was in compliance with OECD test guideline 439. The results showed that the initial Ag concentration in the tested nanoproducts ranged between 0.0058 and 94 µg/g. However, particulate Ag was only found in two products, both of a liquid formulation. Silver penetration through a PES membrane (0.12–53 % by weight) was weakly correlated with the initial Ag concentration in each sample, but more so to the product formulation. The liquid products demonstrated the highest percent of average Ag penetration, followed by the semi-solid and solid formulations, respectively. In contrast, neither any Ag diffusion from these products into the RhE tissue nor any irritation or toxicity was detected. This study suggests a screening method to evaluate the Ag level in products and their potential adverse effects on the skin that could be incorporated as a part of risk assessment for nanotechnology products

  16. Personal exposure control using TLD

    International Nuclear Information System (INIS)

    Ishiguro, Hideharu; Takeda, Shinso

    1979-01-01

    In the Tokai Works of the Power Reactor and Nuclear Fuel Development Corporation (PNC), for personal exposure control, the switching from film badges to TLD badges (and also finger-ring type local dosimeters) was made in fiscal 1974. The facilities involved are a fuel reprocessing plant, a PuO 2 -UO 2 mixed fuel production facility, and a centrifugal uranium enrichment development facility. The types of radiation concerned are various, such as γ(x), β and n. The situation of personal exposure control with TLD and the dose evaluation methods for respective radiations are explained. The number of personnel subject to exposure control, including transient people, is about 2500 - 3000 per three months. The TLD badges used are a special PNC type with TLDs to measure separately γ(x), β and n. With casings made of ABS resin, the external dimensions are 76 mm x 46 mm. (J.P.N.)

  17. A study of health effect estimates using competing methods to model personal exposures to ambient PM2.5.

    Science.gov (United States)

    Strand, Matthew; Hopke, Philip K; Zhao, Weixiang; Vedal, Sverre; Gelfand, Erwin; Rabinovitch, Nathan

    2007-09-01

    Various methods have been developed recently to estimate personal exposures to ambient particulate matter less than 2.5 microm in diameter (PM2.5) using fixed outdoor monitors as well as personal exposure monitors. One class of estimators involves extrapolating values using ambient-source components of PM2.5, such as sulfate and iron. A key step in extrapolating these values is to correct for differences in infiltration characteristics of the component used in extrapolation (such as sulfate within PM2.5) and PM2.5. When this is not done, resulting health effect estimates will be biased. Another class of approaches involves factor analysis methods such as positive matrix factorization (PMF). Using either an extrapolation or a factor analysis method in conjunction with regression calibration allows one to estimate the direct effects of ambient PM2.5 on health, eliminating bias caused by using fixed outdoor monitors and estimated personal ambient PM2.5 concentrations. Several forms of the extrapolation method are defined, including some new ones. Health effect estimates that result from the use of these methods are compared with those from an expanded PMF analysis using data collected from a health study of asthmatic children conducted in Denver, Colorado. Examining differences in health effect estimates among the various methods using a measure of lung function (forced expiratory volume in 1 s) as the health indicator demonstrated the importance of the correction factor(s) in the extrapolation methods and that PMF yielded results comparable with the extrapolation methods that incorporated correction factors.

  18. Personal Exposure in Displacement Ventilated Rooms

    DEFF Research Database (Denmark)

    Brohus, Henrik; Nielsen, Peter Vilhelm

    1996-01-01

    in the lower part of the room close to the occupant. A personal exposure model for displacement ventilated rooms is proposed. The model takes the influence of gradients and the human thermal boundary layer into account. Two new quantities describing the interaction between a person and the ventilation......Personal exposure in a displacement ventilated room is examined. The stratified flow and the considerable concentration gradients necessitate an improvement of the widely used fully mixing compartmental approach. The exposure of a seated and a standing person in proportion to the stratification...... contaminant sources, this entrainment improves the indoor air quality. Measurements of exposure due to a passive contaminant source show a significant dependence on the flow field as well as on the contaminant source location. Poor system performance is found in the case of a passive contaminant released...

  19. Progress in cadmium-related health effects in persons with high environmental exposure in northwestern Thailand: A five-year follow-up

    International Nuclear Information System (INIS)

    Swaddiwudhipong, Witaya; Limpatanachote, Pisit; Mahasakpan, Pranee; Krintratun, Somyot; Punta, Boonyarat; Funkhiew, Thippawan

    2012-01-01

    Food-borne cadmium was the principal source of exposure for persons living in the 12 cadmium-contaminated villages in Mae Sot District, Tak Province, northwestern Thailand. This report presents progress in cadmium-related health effects among persons with high cadmium exposure. The study included 436 persons who had urinary cadmium levels ≥5 μg/g creatinine and were screened for urinary cadmium, renal function, hypertension, diabetes and urinary stones in 2005 (baseline) and 2010 (5-year follow-up). Study renal biomarkers included urinary excretion of β 2 -microglobulin (β 2 -MG), total protein and calcium, serum creatinine and glomerular filtration rate (GFR). The geometric mean level of urinary cadmium statistically significantly reduced from 9.5±1.6 μg/g creatinine in 2005 to 8.8±1.6 μg/g creatinine in 2010. Compared to baseline, the follow-up examination revealed significant increases in urinary β 2 -MG (tubular effect), urinary total protein and serum creatinine, and a decrease in GFR (glomerular effects). Progressive renal dysfunctions were similarly observed in persons both with and without reduction in cadmium intake. Significant increases in prevalence of hypertension, diabetes and urinary stones were also detected at follow-up. These three disorders were found to markedly impair renal functions in the study persons. Our study indicates that in persons with prolonged excessive cadmium exposure, toxic health effects may progress even after exposure reduction. Renal damage from cadmium can be due to its direct nephrotoxic effect and also through the related disorders causing nephropathy.

  20. Progress in cadmium-related health effects in persons with high environmental exposure in northwestern Thailand: A five-year follow-up

    Energy Technology Data Exchange (ETDEWEB)

    Swaddiwudhipong, Witaya, E-mail: swaddi@hotmail.com [Department of Community and Social Medicine, Mae Sot General Hospital, Tak 63110 (Thailand); Limpatanachote, Pisit [Department of Internal Medicine, Mae Sot General Hospital, Tak 63110 (Thailand); Mahasakpan, Pranee [Department of Community and Social Medicine, Mae Sot General Hospital, Tak 63110 (Thailand); Krintratun, Somyot [Department of Internal Medicine, Mae Sot General Hospital, Tak 63110 (Thailand); Punta, Boonyarat; Funkhiew, Thippawan [Department of Community and Social Medicine, Mae Sot General Hospital, Tak 63110 (Thailand)

    2012-01-15

    Food-borne cadmium was the principal source of exposure for persons living in the 12 cadmium-contaminated villages in Mae Sot District, Tak Province, northwestern Thailand. This report presents progress in cadmium-related health effects among persons with high cadmium exposure. The study included 436 persons who had urinary cadmium levels {>=}5 {mu}g/g creatinine and were screened for urinary cadmium, renal function, hypertension, diabetes and urinary stones in 2005 (baseline) and 2010 (5-year follow-up). Study renal biomarkers included urinary excretion of {beta}{sub 2}-microglobulin ({beta}{sub 2}-MG), total protein and calcium, serum creatinine and glomerular filtration rate (GFR). The geometric mean level of urinary cadmium statistically significantly reduced from 9.5{+-}1.6 {mu}g/g creatinine in 2005 to 8.8{+-}1.6 {mu}g/g creatinine in 2010. Compared to baseline, the follow-up examination revealed significant increases in urinary {beta}{sub 2}-MG (tubular effect), urinary total protein and serum creatinine, and a decrease in GFR (glomerular effects). Progressive renal dysfunctions were similarly observed in persons both with and without reduction in cadmium intake. Significant increases in prevalence of hypertension, diabetes and urinary stones were also detected at follow-up. These three disorders were found to markedly impair renal functions in the study persons. Our study indicates that in persons with prolonged excessive cadmium exposure, toxic health effects may progress even after exposure reduction. Renal damage from cadmium can be due to its direct nephrotoxic effect and also through the related disorders causing nephropathy.

  1. The Mere Exposure Instruction Effect.

    Science.gov (United States)

    Van Dessel, Pieter; Mertens, Gaëtan; Smith, Colin Tucker; De Houwer, Jan

    2017-09-01

    The mere exposure effect refers to the well-established finding that people evaluate a stimulus more positively after repeated exposure to that stimulus. We investigated whether a change in stimulus evaluation can occur also when participants are not repeatedly exposed to a stimulus, but are merely instructed that one stimulus will occur frequently and another stimulus will occur infrequently. We report seven experiments showing that (1) mere exposure instructions influence implicit stimulus evaluations as measured with an Implicit Association Test (IAT), personalized Implicit Association Test (pIAT), or Affect Misattribution Procedure (AMP), but not with an Evaluative Priming Task (EPT), (2) mere exposure instructions influence explicit evaluations, and (3) the instruction effect depends on participants' memory of which stimulus will be presented more frequently. We discuss how these findings inform us about the boundary conditions of mere exposure instruction effects, as well as the mental processes that underlie mere exposure and mere exposure instruction effects.

  2. Personal exposure to ultrafine particles and oxidative DNA damage

    DEFF Research Database (Denmark)

    Vinzents, Peter S; Møller, Peter; Sørensen, Mette

    2005-01-01

    Exposure to ultrafine particles (UFPs) from vehicle exhaust has been related to risk of cardiovascular and pulmonary disease and cancer, even though exposure assessment is difficult. We studied personal exposure in terms of number concentrations of UFPs in the breathing zone, using portable instr......, particularly during bicycling in traffic. The results indicate that biologic effects of UFPs occur at modest exposure, such as that occurring in traffic, which supports the relationship of UFPs and the adverse health effects of air pollution.......Exposure to ultrafine particles (UFPs) from vehicle exhaust has been related to risk of cardiovascular and pulmonary disease and cancer, even though exposure assessment is difficult. We studied personal exposure in terms of number concentrations of UFPs in the breathing zone, using portable...... instruments in six 18-hr periods in 15 healthy nonsmoking subjects. Exposure contrasts of outdoor pollution were achieved by bicycling in traffic for 5 days and in the laboratory for 1 day. Oxidative DNA damage was assessed as strand breaks and oxidized purines in mononuclear cells isolated from venous blood...

  3. Personal exposure to ultrafine particles and oxidative DNA damage

    DEFF Research Database (Denmark)

    Vinzents, Peter S; Møller, Peter; Sørensen, Mette

    2005-01-01

    10), nitrous oxide, nitrogen dioxide, carbon monoxide, and/or number concentration of UFPs at urban background or busy street monitoring stations was not a significant predictor of DNA damage, although personal UFP exposure was correlated with urban background concentrations of CO and NO2...... the morning after exposure measurement. Cumulated outdoor and cumulated indoor exposures to UFPs each were independent significant predictors of the level of purine oxidation in DNA but not of strand breaks. Ambient air concentrations of particulate matter with an aerodynamic diameter of ..., particularly during bicycling in traffic. The results indicate that biologic effects of UFPs occur at modest exposure, such as that occurring in traffic, which supports the relationship of UFPs and the adverse health effects of air pollution....

  4. Development of a method for personal, spatiotemporal exposure assessment.

    Science.gov (United States)

    Adams, Colby; Riggs, Philip; Volckens, John

    2009-07-01

    This work describes the development and evaluation of a high resolution, space and time-referenced sampling method for personal exposure assessment to airborne particulate matter (PM). This method integrates continuous measures of personal PM levels with the corresponding location-activity (i.e. work/school, home, transit) of the subject. Monitoring equipment include a small, portable global positioning system (GPS) receiver, a miniature aerosol nephelometer, and an ambient temperature monitor to estimate the location, time, and magnitude of personal exposure to particulate matter air pollution. Precision and accuracy of each component, as well as the integrated method performance were tested in a combination of laboratory and field tests. Spatial data was apportioned into pre-determined location-activity categories (i.e. work/school, home, transit) with a simple, temporospatially-based algorithm. The apportioning algorithm was extremely effective with an overall accuracy of 99.6%. This method allows examination of an individual's estimated exposure through space and time, which may provide new insights into exposure-activity relationships not possible with traditional exposure assessment techniques (i.e., time-integrated, filter-based measurements). Furthermore, the method is applicable to any contaminant or stressor that can be measured on an individual with a direct-reading sensor.

  5. Personal exposure versus monitoring station data for respirable particles

    Energy Technology Data Exchange (ETDEWEB)

    Sega, K; Fugas, M

    1982-01-01

    Personal exposure to respirable particles of 12 subjects working at the same location, but living in various parts of Zagreb, was monitored for 7 consecutive days and compared with simultaneously obtained data from the outdoor network station nearest to subject's home. Although personal exposure is related to the outdoor pollution, other sources play a considerable role. Indoor exposure takes, on the average, more than 80% of the total time. The ratio between average personal exposure and respirable particle levels in the outdoor air decreases with the increased outdoor concentration (r = -0.93), indicating that this relationship might serve as a basis for a rough estimate of possible personal exposure.

  6. Integrating local urban climate modelling and mobile sensor data for personal exposure assessments in the context of urban heat island effect

    Science.gov (United States)

    Ueberham, Maximilian; Hertel, Daniel; Schlink, Uwe

    2017-04-01

    Deeper knowledge about urban climate conditions is getting more important in the context of climate change, urban population growth, urban compaction and continued surface sealing. Especially the urban heat island effect (UHI) is one of the most significant human induced alterations of Earth's surface climate. According to this the appearance frequency of heat waves in cities will increase with deep impacts on personal thermal comfort, human health and local residential quality of citizens. UHI can be very heterogenic within a city and research needs to focus more on the neighborhood scale perspective to get further insights about the heat burden of individuals. However, up to now, few is known about local thermal environmental variances and personal exposure loads. To monitor these processes and the impact on individuals, improved monitoring approaches are crucial, complementing data recorded at conventional fixed stations. Therefore we emphasize the importance of micro-meteorological modelling and mobile measurements to shed new light on the nexus of urban human-climate interactions. Contributing to this research we jointly present the approaches of our two PhD-projects. Firstly we illustrate on the basis of an example site, how local thermal conditions in an urban district can be simulated and predicted by a micro-meteorological model. Secondly we highlight the potentials of personal exposure measurements based on an evaluation of mobile micro-sensing devices (MSDs) and analyze and explain differences between model predictions and mobile records. For the examination of local thermal conditions we calculated ENVI-met simulations within the "Bayerischer Bahnhof" quarter in Leipzig (Saxony, Germany; 51°20', 12°22'). To accomplish the maximum temperature contrasts within the diverse built-up structures we chose a hot summer day (25 Aug 2016) under autochthonous weather conditions. From these simulations we analyzed a UHI effect between the model core (urban area

  7. Cardiovascular Effects of Long-Term Exposure to Air Pollution: A Population-Based Study With 900 845 Person-Years of Follow-up.

    Science.gov (United States)

    Kim, Hyeanji; Kim, Joonghee; Kim, Sunhwa; Kang, Si-Hyuck; Kim, Hee-Jun; Kim, Ho; Heo, Jongbae; Yi, Seung-Muk; Kim, Kyuseok; Youn, Tae-Jin; Chae, In-Ho

    2017-11-08

    Studies have shown that long-term exposure to air pollution such as fine particulate matter (≤2.5 μm in aerodynamic diameter [PM 2.5 ]) increases the risk of all-cause and cardiovascular mortality. To date, however, there are limited data on the impact of air pollution on specific cardiovascular diseases. This study aimed to evaluate cardiovascular effects of long-term exposure to air pollution among residents of Seoul, Korea. Healthy participants with no previous history of cardiovascular disease were evaluated between 2007 and 2013. Exposure to air pollutants was estimated by linking the location of outdoor monitors to the ZIP code of each participant's residence. Crude and adjusted analyses were performed using Cox regression models to evaluate the risk for composite cardiovascular events including cardiovascular mortality, acute myocardial infarction, congestive heart failure, and stroke. A total of 136 094 participants were followed for a median of 7.0 years (900 845 person-years). The risk of major cardiovascular events increased with higher mean concentrations of PM 2.5 in a linear relationship, with a hazard ratio of 1.36 (95% confidence interval, 1.29-1.43) per 1 μg/m 3 PM 2.5 . Other pollutants including PM 2.5-10 of CO, SO 2 , and NO 2 , but not O 3 , were significantly associated with increased risk of cardiovascular events. The burden from air pollution was comparable to that from hypertension and diabetes mellitus. This large-scale population-based study demonstrated that long-term exposure to air pollution including PM 2.5 increases the risk of major cardiovascular disease and mortality. Air pollution should be considered an important modifiable environmental cardiovascular risk factor. © 2017 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

  8. Sensitivity Analysis of Personal Exposure Assessment Using a Computer Simulated Person

    DEFF Research Database (Denmark)

    Brohus, Henrik; Jensen, H. K.

    2009-01-01

    The paper considers uncertainties related to personal exposure assessment using a computer simulated person. CFD is used to simulate a uniform flow field around a human being to determine the personal exposure to a contaminant source. For various vertical locations of a point contaminant source...... three additional factors are varied, namely the velocity, details of the computer simulated person, and the CFD model of the wind channel. The personal exposure is found to be highly dependent on the relative source location. Variation in the range of two orders of magnitude is found. The exposure...

  9. Personality, depressive symptoms and prior trauma exposure of new ...

    African Journals Online (AJOL)

    Background. Police officers are predisposed to trauma exposure. The development of depression and post-traumatic stress disorder (PTSD) may be influenced by personality style, prior exposure to traumatic events and prior depression. Objectives. To describe the personality profiles of new Metropolitan Police Service ...

  10. EVALUATION OF A PERSONAL NEPHELOMETER FOR HUMAN EXPOSURE MONITORING

    Science.gov (United States)

    Current particulate matter (PM) exposure studies are using continuous personal nephelometers (pDR-1000, MIE, Inc.) to measure human exposure to PM. The personal nephelometer is a passive sampler which uses light scattering technology to measure particles ranging in size from 0....

  11. Measurement of personal exposure to volatile organic compounds and particle associated PAH in three UK regions.

    Science.gov (United States)

    Saborit, Juana Mari Delgado; Aquilina, Noel J; Meddings, Claire; Baker, Stephen; Vardoulakis, Sotiris; Harrison, Roy M

    2009-06-15

    Personal exposures to 15 volatile organic compounds (VOC) and 16 polycyclic aromatic hydrocarbons (PAH) of 100 adult nonsmokers living in three UK areas, namely London, West Midlands, and rural South Wales, were measured using an actively pumped sampler carried around by the volunteers for 5/1 (VOC/PAH) consecutive 24-h periods, following their normal lifestyle. Results from personal exposure measurements categorized by geographical location, type of dwelling, and exposure to environmental tobacco smoke (ETS) are presented. The average personal exposure concentration to benzene, 1,3-butadiene, and benzo(a)pyrene representing the main carcinogenic components of the VOC and PAH mixture were 2.2 +/- 2.5 microg/m3, 0.4 +/- 0.7 microg/m3, and 0.3 +/- 0.7 ng/m3 respectively. The association of a number of generic factors with personal exposure concentrations was investigated, including first-line property, traffic, the presence of an integral garage, and ETS. Only living in houses with integral garages and being exposed to ETS were identified as unequivocal contributors to VOC personal exposure, while only ETS had a clear effect upon PAH personal exposures. The measurements of personal exposures were compared with health-based European and UK air quality guidelines, with some exceedences occurring. Activities contributing to high personal exposures included the use of a fireplace in the home, ETS exposure, DIY (i.e., construction and craftwork activities), and photocopying, among others.

  12. Effects of smartphone diaries and personal dosimeters on behavior in a randomized study of methods to document sunlight exposure

    DEFF Research Database (Denmark)

    Køster, Brian; Søndergaard, Jens; Nielsen, Jesper Bo

    2016-01-01

    study. We examined the effects of wearing dosimeters and filling out diaries, measurement period and recall effect on the sun-related behavior in Denmark in 2012.Our sample included 240 participants eligible by smartphone status and who took a vacation during weeks 26-32 in 2012, randomized by gender...

  13. Exposure Due to Interacting Air flows Between Two Persons

    DEFF Research Database (Denmark)

    Bjørn, Erik; Nielsen, Peter V.

    The contaminant concentration inhaled by an occupant (ie. the personal exposure) is usually less than the return concentration in displacement ventilated rooms. Two main questions are investigated: 1) Does the exhalation from one person penetrate the breathing zone of another person placed nearby...

  14. Personal Exposure to Contaminant Sources in Ventilated Rooms

    DEFF Research Database (Denmark)

    Brohus, Henrik

    Three different tools for personal exposure assessment are presented. They are all able to consider the local influence of persons in ventilated rooms where concentration gradients prevail: A Breathing Thermal Manikin, a Computer Simulated Person, and a Trained Sensory Panel. The tools are applied...

  15. Personal exposures of preschool children to carbon monoxide and nitrogen dioxide. The role of gas stoves

    Energy Technology Data Exchange (ETDEWEB)

    Alm, S.; Jantunen, M.J.; Mukala, K.; Tuomisto, J. [National Public Health Institute, Kuopio (Finland). Div. of Environmental Health; Pasanen, P. [Kuopio Univ. (Finland)

    1993-12-31

    Personal 1-h mean CO exposures of preschool children in two day care centers of Helsinki were measured with continuously recording personal exposure monitors, and their personal 1-wk NO{sub 2} exposures with Palmes tubes. The results were compared to fixed site ambient air monitoring results and related to the presence of high CO, low heat value town gas fired stoves in the homes of the children. Results show that fixed site ambient air monitors are of little value in predicting personal exposures of children or even their relative differences between areas, and also that town gas fired stoves have a profound effect on the CO exposures, and little or no effect on the NO{sub 2} exposures of the children. (author)

  16. Contribution of various microenvironments to the daily personal exposure to ultrafine particles: Personal monitoring coupled with GPS tracking

    Science.gov (United States)

    Bekö, Gabriel; Kjeldsen, Birthe Uldahl; Olsen, Yulia; Schipperijn, Jasper; Wierzbicka, Aneta; Karottki, Dorina Gabriela; Toftum, Jørn; Loft, Steffen; Clausen, Geo

    2015-06-01

    Exposure to ultrafine particles (UFP) may have adverse health effects. Central monitoring stations do not represent the personal exposure to UFP accurately. Few studies have previously focused on personal exposure to UFP. Sixty non-smoking residents living in Copenhagen, Denmark were asked to carry a backpack equipped with a portable monitor, continuously recording particle number concentrations (PN), in order to measure the real-time individual exposure over a period of ˜48 h. A GPS logger was carried along with the particle monitor and allowed us to estimate the contribution of UFP exposure occurring in various microenvironments (residence, during active and passive transport, other indoor and outdoor environments) to the total daily exposure. On average, the fractional contribution of each microenvironment to the daily integrated personal exposure roughly corresponded to the fractions of the day the subjects spent in each microenvironment. The home environment accounted for 50% of the daily personal exposure. Indoor environments other than home or vehicles contributed with ˜40%. The highest median UFP concentration was obtained during passive transport (vehicles). However, being in transit or outdoors contributed 5% or less to the daily exposure. Additionally, the subjects recorded in a diary the periods when they were at home. With this approach, 66% of the total daily exposure was attributable to the home environment. The subjects spent 28% more time at home according to the diary, compared to the GPS. These results may indicate limitations of using diaries, but also possible inaccuracy and miss-classification in the GPS data.

  17. Guidelines for personal exposure monitoring of chemicals: Part III.

    Science.gov (United States)

    Hashimoto, Haruo; Yamada, Kenichi; Hori, Hajime; Kumagai, Shinji; Murata, Masaru; Nagoya, Toshio; Nakahara, Hirohiko; Mochida, Nobuyuki

    2018-01-25

    This Document, "Guidelines for personal exposure monitoring of chemicals" ("this Guideline"), has been prepared by "The Committee for Personal Exposure Monitoring" ("the Committee") of the Expert Division of Occupational Hygiene & Ergonomics, Japan Society for Occupational Health. Considering the background of the growing importance of personal exposure monitoring in risk assessment and the need to prepare for the introduction of monitoring using personal samplers from an administrative perspective in recent years, the Committee was organized in November 2012. The Committee has prepared this Guideline as a "practical guideline" for personal exposure monitoring, so as to offer proposals and recommendations to the members of the Japan Society for Occupational Health and to society in general. The scope of this Guideline covers all chemical substances and all related workplaces regarded as targets for general assessment and the management of risk. It thus is not to be considered to comment on legal regulations and methodology. The main text provides the basic methods and concepts of personal exposure monitoring, while 31 "Appendices" are provided in this Guideline throughout the series; technical descriptions, statistical bases, and actual workplace examples are provided in these appendices, to assist better understanding. The personal exposure monitoring described as per this Guideline is equivalent to an "expert-centered basic method to reasonably proceed with the assessment and management of risk at workplaces." It is considered that practicing and expanding on this method will significantly contribute in reforming the overall framework of occupational hygiene management in Japan.

  18. Guidelines for personal exposure monitoring of chemicals: Part IV.

    Science.gov (United States)

    Hashimoto, Haruo; Yamada, Kenichi; Hori, Hajime; Kumagai, Shinji; Murata, Masaru; Nagoya, Toshio; Nakahara, Hirohiko; Mochida, Nobuyuki

    2018-03-27

    This Document, "Guidelines for personal exposure monitoring of chemicals" ("this Guideline"), has been prepared by "The Committee for Personal Exposure Monitoring" ("the Committee") of the Expert Division of Occupational Hygiene & Ergonomics, Japan Society for Occupational Health. Considering the background of the growing importance of personal exposure monitoring in risk assessment and the need to prepare for the introduction of monitoring using personal samplers from an administrative perspective in recent years, the Committee was organized in November 2012. The Committee has prepared this Guideline as a "practical guideline" for personal exposure monitoring, so as to offer proposals and recommendations to the members of the Japan Society for Occupational Health and to society in general. The scope of this Guideline covers all chemical substances and all related workplaces regarded as targets for general assessment and the management of risk. It thus is not to be considered to comment on legal regulations and methodology. The main text provides the basic methods and concepts of personal exposure monitoring, while 31 "Appendices" are provided in this Guideline throughout the series; technical descriptions, statistical bases, and actual workplace examples are provided in these appendices, to assist better understanding. The personal exposure monitoring described as per this Guideline is equivalent to an "expert-centered basic method to reasonably proceed with the assessment and management of risk at workplaces." It is considered that practicing and expanding on this method will significantly contribute in reforming the overall framework of occupational hygiene management in Japan.

  19. Guidelines for personal exposure monitoring of chemicals: Part II.

    Science.gov (United States)

    Hashimoto, Haruo; Yamada, Kenichi; Hori, Hajime; Kumagai, Shinji; Murata, Masaru; Nagoya, Toshio; Nakahara, Hirohiko; Mochida, Nobuyuki

    2017-11-25

    This Document, "Guidelines for personal exposure monitoring of chemicals" ("this Guideline"), has been prepared by "The Committee for Personal Exposure Monitoring" ("the Committee") of the Expert Division of Occupational Hygiene & Ergonomics, Japan Society for Occupational Health. Considering the background of the growing importance of personal exposure monitoring in risk assessment and the need to prepare for the introduction of monitoring using personal samplers from an administrative perspective in recent years, the Committee was organized in November 2012. The Committee has prepared this Guideline as a "practical guideline" for personal exposure monitoring, so as to offer proposals and recommendations to the members of the Japan Society for Occupational Health and to society in general. The scope of this Guideline covers all chemical substances and all related workplaces regarded as targets for general assessment and the management of risk. It thus is not to be considered to comment on legal regulations and methodology. The main text provides the basic methods and concepts of personal exposure monitoring, while 31 "Appendices" are provided in this Guideline throughout the series; technical descriptions, statistical bases, and actual workplace examples are provided in these appendices, to assist better understanding. The personal exposure monitoring described as per this Guideline is equivalent to an "expert-centered basic method to reasonably proceed with the assessment and management of risk at workplaces." It is considered that practicing and expanding on this method will significantly contribute in reforming the overall framework of occupational hygiene management in Japan.

  20. Guidelines for personal exposure monitoring of chemicals: Part I.

    Science.gov (United States)

    Hashimoto, Haruo; Yamada, Kenichi; Hori, Hajime; Kumagai, Shinji; Murata, Masaru; Nagoya, Toshio; Nakahara, Hirohiko; Mochida, Nobuyuki

    2017-09-28

    This Document, "Guidelines for personal exposure monitoring of chemicals" ("this Guideline"), has been prepared by "The Committee for Personal Exposure Monitoring" ("the Committee") of the Expert Division of Occupational Hygiene & Ergonomics, Japan Society for Occupational Health. Considering the background of the growing importance of personal exposure monitoring in risk assessment and the need to prepare for the introduction of monitoring using personal samplers from an administrative perspective in recent years, the Committee was organized in November 2012. The Committee has prepared this Guideline as a "practical guideline" for personal exposure monitoring, so as to offer proposals and recommendations to the members of the Japan Society for Occupational Health and to society in general. The scope of this Guideline covers all chemical substances and all related workplaces regarded as targets for general assessment and the management of risk. It thus is not to be considered to comment on legal regulations and methodology. The main text provides the basic methods and concepts of personal exposure monitoring, while 31 "Appendices" are provided later in this Guideline throughout the series; technical descriptions, statistical bases, and actual workplace examples are provided in these appendices, to assist better understanding. The personal exposure monitoring described as per this Guideline is equivalent to an "expert-centered basic method to reasonably proceed with the assessment and management of risk at workplaces." It is considered that practicing and expanding on this method will significantly contribute in reforming the overall framework of occupational hygiene management in Japan.

  1. Guidelines for personal exposure monitoring of chemicals: Part V.

    Science.gov (United States)

    Hashimoto, Haruo; Yamada, Kenichi; Hori, Hajime; Kumagai, Shinji; Murata, Masaru; Nagoya, Toshio; Nakahara, Hirohiko; Mochida, Nobuyuki

    2018-05-25

    This Document, "Guidelines for personal exposure monitoring of chemicals" ("this Guideline"), has been prepared by "The Committee for Personal Exposure Monitoring" ("the Committee") of the Expert Division of Occupational Hygiene & Ergonomics, Japan Society for Occupational Health. Considering the background of the growing importance of personal exposure monitoring in risk assessment and the need to prepare for the introduction of monitoring using personal samplers from an administrative perspective in recent years, the Committee was organized in November 2012. The Committee has prepared this Guideline as a "practical guideline" for personal exposure monitoring, so as to offer proposals and recommendations to the members of the Japan Society for Occupational Health and to society in general. The scope of this Guideline covers all chemical substances and all related workplaces regarded as targets for general assessment and the management of risk. It thus is not to be considered to comment on legal regulations and methodology. The main text provides the basic methods and concepts of personal exposure monitoring, while 31 "Appendices" are provided in this Guideline throughout the series; technical descriptions, statistical bases, and actual workplace examples are provided in these appendices, to assist better understanding. The personal exposure monitoring described as per this Guideline is equivalent to an "expert-centered basic method to reasonably proceed with the assessment and management of risk at workplaces." It is considered that practicing and expanding on this method will significantly contribute in reforming the overall framework of occupational hygiene management in Japan.

  2. Real-time personal exposure and health condition monitoring system

    Energy Technology Data Exchange (ETDEWEB)

    Saitou, Isamu; Kanda, Hiroaki; Asai, Akio; Takeishi, Naoki; Ota, Yoshito [Hitachi Aloka Medical, Ltd., Measuring Systems Engineering Dept., Tokyo (Japan); Hanawa, Nobuhiro; Ueda, Hisao; Kusunoki, Tsuyoshi; Ishitsuka, Etsuo; Kawamura, Hiroshi [Japan Atomic Energy Agency, Oarai Research and Development Center, Oarai, Ibaraki (Japan)

    2012-03-15

    JAEA (Japan Atomic Energy Agency) and HAM (Hitachi Aloka Medical, Ltd) have proposed novel monitoring system for workers of nuclear facility. In these facilities, exposure management for workers is mainly used access control and personal exposure recordings. This system is currently only for reports management but is not confirmative for surveillance when work in progress. Therefore, JAEA and HAM integrate access control and personal exposure recordings and two real-time monitoring systems which are position sensing and vital sign monitor. Furthermore change personal exposure management to real-time management, this system integration prevents workers from risk of accidents, and makes possible take appropriate action quickly. This novel system is going to start for tentative operation, using position sensing and real-time personal dosimeter with database in Apr. 2012. (author)

  3. Personal and ambient PM2.5 exposure assessment in the city of Agra

    Directory of Open Access Journals (Sweden)

    M. Habil

    2016-03-01

    Full Text Available Human exposure to fine particles can have significant harmful effects on the respiratory and cardiovascular system. To investigate daily exposure characteristics to PM2.5 with ambient concentrations in an urban environment, a personal exposure measurements were conducted for school children, office workers and at their residents, in the city of Taj ‘Agra’, India. In order to account for all the sources of particulate matter exposure, measurements on several different days during December 2013 to February 2014 were carried out. Personal environment monitors (PEM and APM 550 were used to measure PM2.5 concentration. The research findings provide insight into possible sources and their interaction with human activities in modifying the human exposure levels. Keywords: Personal exposure, PM2.5, Ambient concentration, Correlation analysis, Health effects

  4. Descriptive survey of personal hygiene and knowledge of exposure ...

    African Journals Online (AJOL)

    Majority of the poultry workers have adequate personal hygiene while use of antiseptics as part of hand washing practices is relatively low. Forty-three percent of poultry workers have some knowledge of occupational exposure factors and 27.3% have some knowledge of non-occupational exposure factors to zoonotic ...

  5. Personal exposure to inhalable cement dust among construction workers.

    NARCIS (Netherlands)

    Peters, S.M.; Thomassen, Y.; Fechter-Rink, E.; Kromhout, H.

    2009-01-01

    Objective- A case study was carried out to assess cement dust exposure and its determinants among construction workers and for comparison among workers in cement and concrete production.Methods- Full-shift personal exposure measurements were performed and samples were analysed for inhalable dust and

  6. 46 CFR 197.540 - Determination of personal exposure.

    Science.gov (United States)

    2010-10-01

    ... repeated for the operation when there has been a change in the procedure, equipment, or work practices of... when personal exposure has returned to the level that existed before the emergency. There must be... monitoring upon reasonable belief that the PEL's are being exceeded. (e) Notification of exposure monitoring...

  7. Personal radiofrequency electromagnetic field exposure measurements in Swiss adolescents.

    Science.gov (United States)

    Roser, Katharina; Schoeni, Anna; Struchen, Benjamin; Zahner, Marco; Eeftens, Marloes; Fröhlich, Jürg; Röösli, Martin

    2017-02-01

    Adolescents belong to the heaviest users of wireless communication devices, but little is known about their personal exposure to radiofrequency electromagnetic fields (RF-EMF). The aim of this paper is to describe personal RF-EMF exposure of Swiss adolescents and evaluate exposure relevant factors. Furthermore, personal measurements were used to estimate average contributions of various sources to the total absorbed RF-EMF dose of the brain and the whole body. Personal exposure was measured using a portable RF-EMF measurement device (ExpoM-RF) measuring 13 frequency bands ranging from 470 to 3600MHz. The participants carried the device for three consecutive days and kept a time-activity diary. In total, 90 adolescents aged 13 to 17years participated in the study conducted between May 2013 and April 2014. In addition, personal measurement values were combined with dose calculations for the use of wireless communication devices to quantify the contribution of various RF-EMF sources to the daily RF-EMF dose of adolescents. Main contributors to the total personal RF-EMF measurements of 63.2μW/m 2 (0.15V/m) were exposures from mobile phones (67.2%) and from mobile phone base stations (19.8%). WLAN at school and at home had little impact on the personal measurements (WLAN accounted for 3.5% of total personal measurements). According to the dose calculations, exposure from environmental sources (broadcast transmitters, mobile phone base stations, cordless phone base stations, WLAN access points, and mobile phones in the surroundings) contributed on average 6.0% to the brain dose and 9.0% to the whole-body dose. RF-EMF exposure of adolescents is dominated by their own mobile phone use. Environmental sources such as mobile phone base stations play a minor role. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. Psychiatric symptomatology in persons with organic solvent exposure.

    Science.gov (United States)

    Morrow, L A; Kamis, H; Hodgson, M J

    1993-02-01

    This study investigated psychiatric symptomatology, self-concept, locus of control, and daily events in persons with a history of exposure to mixtures of organic solvents. Exposed subjects were more likely than controls to report depression, anxiety, fatigue, confusion, and somatic concerns, which in turn were associated with certain exposure-related variables (e.g., cacosmia). There were no differences between the groups in self-concept, locus of control, or ratings of daily hassles and uplifts. Exposed persons may be able to accurately identify what they perceive as changes that are due to the exposure (e.g., anxiety) without attributing these specific adverse outcomes to dispositional variables.

  9. Indoor, outdoor, and personal exposure monitoring of particulate air pollution: the Baltimore elderly epidemiology-exposure pilot study

    Science.gov (United States)

    Williams, Ron; Creason, John; Zweidinger, Roy; Watts, Randall; Sheldon, Linda; Shy, Carl

    A 17-day pilot study investigating potential PM exposures of an elderly population was conducted near Baltimore, Maryland. Collection of residential indoor, residential outdoor, and ambient monitoring data associated with the subjects living at a common retirement facility was integrated with results from a paired epidemiological pilot study. This integration was used to investigate the potential pathophysiological health effects resulting from daily changes in estimated PM exposures with results reported elsewhere. Objectives of the exposure study were to determine the feasibility of performing PM exposure assessment upon an elderly population and establishing relationships between the various exposure measures including personal monitoring. PM 2.5 was determined to be the dominant outdoor size fraction (0.83 PM 2.5/PM 10 mass ratio by dichot monitoring). Individual 24-h PM 1.5 personal exposures ranged from 12 to 58 μg m -3. Comparison of data from matched sampling dates resulted in mean daily PM 1.5 personal, PM 2.5 outdoor, and PM 1.5 indoor concentrations of 34, 17, and 17 μg m -3, respectively. Activity patterns of the study population indicated a generally sedentary population spending a mean of 96% of each day indoors. Future studies would benefit from the use of a consistent sampling methodology across a larger number of PM measurement sites relevant to the elderly subjects, as well as a larger personal PM exposure study population to more successfully collect data needed in matched epidemiological-exposure studies.

  10. Personal exposure to volatile organic compounds in the Czech Republic.

    Science.gov (United States)

    Svecova, Vlasta; Topinka, Jan; Solansky, Ivo; Sram, Radim J

    2012-09-01

    Personal exposures to volatile organic compounds (VOCs) were measured in the three industrial cities in the Czech Republic, Ostrava, Karvina and Havirov, while the city of Prague served as a control in a large-scale molecular epidemiological study identifying the impacts of air pollution on human health. Office workers from Ostrava and city policemen from Karvina, Havirov and Prague were monitored in the winter and summer of 2009. Only adult non-smokers participated in the study (N=160). Radiello-diffusive passive samplers were used to measure the exposure to benzene, toluene, ethylbenzene, meta- plus para-xylene and ortho-xylene (BTEX). All participants completed a personal questionnaire and a time-location-activity diary (TLAD). The average personal BTEX exposure levels in both seasons were 7.2/34.3/4.4/16.1 μg/m(3), respectively. The benzene levels were highest in winter in Karvina, Ostrava and Prague: 8.5, 7.2 and 5.3 μg/m(3), respectively. The personal exposures to BTEX were higher than the corresponding stationary monitoring levels detected in the individual localities (Pfireplace or gas stove, automobile use and being in a restaurant were important predictors for benzene personal exposure. Ostrava's outdoor benzene pollution was a significant factor increasing the exposure of the Ostrava study participants in winter (P<0.05).

  11. Chlorobenzylidenemalonitrile Gas Exposure from A Novelty Personal-Protection Gun

    Directory of Open Access Journals (Sweden)

    Dong, Christopher

    2007-05-01

    Full Text Available We present an unusual case of chlorobenzylidenemalonitrile (CS tear-gas exposure from the unwitting discharge of a personal-protection handgun loaded with CS gas. The gun was in a bag of toys purchased from a local thrift store and was discharged by a child. The responding paramedic presumptively identified the substance as CS based solely on personal experience. This recognition led to suboptimal field management of the incident with the paramedic failing to follow the standard operating procedures for an unknown chemical exposure. As this was a benign agent, there were no serious consequences. This case highlights the pre-hospital and emergency department challenges associated with the management of an unknown chemical exposure and the potential consequences if the chemical is a toxic substance. A methodical approach following established protocols can reduce the potential for negative outcomes. Review of the literature found no other report of CS gas exposure from such a personal-protection weapon.

  12. Time-activity relationships to VOC personal exposure factors

    Science.gov (United States)

    Edwards, Rufus D.; Schweizer, Christian; Llacqua, Vito; Lai, Hak Kan; Jantunen, Matti; Bayer-Oglesby, Lucy; Künzli, Nino

    Social and demographic factors have been found to play a significant role in differences between time-activity patterns of population subgroups. Since time-activity patterns largely influence personal exposure to compounds as individuals move across microenvironments, exposure subgroups within the population may be defined by factors that influence daily activity patterns. Socio-demographic and environmental factors that define time-activity subgroups also define quantifiable differences in VOC personal exposures to different sources and individual compounds in the Expolis study. Significant differences in exposures to traffic-related compounds ethylbenzene, m- and p-xylene and o-xylene were observed in relation to gender, number of children and living alone. Categorization of exposures further indicated time exposed to traffic at work and time in a car as important determinants. Increased exposures to decane, nonane and undecane were observed for males, housewives and self-employed. Categorization of exposures indicated exposure subgroups related to workshop use and living downtown. Higher exposures to 3-carene and α-pinene commonly found in household cleaning products and fragrances were associated with more children, while exposures to traffic compounds ethylbenzene, m- and p-xylene and o-xylene were reduced with more children. Considerable unexplained variation remained in categorization of exposures associated with home product use and fragrances, due to individual behavior and product choice. More targeted data collection methods in VOC exposure studies for these sources should be used. Living alone was associated with decreased exposures to 2-methyl-1-propanol and 1-butanol, and traffic-related compounds. Identification of these subgroups may help to reduce the large amount of unexplained variation in VOC exposure studies. Further they may help in assessing impacts of urban planning that result in changes in behavior of individuals, resulting in shifts in

  13. Towards Personal Exposures: How Technology Is Changing Air Pollution and Health Research.

    Science.gov (United States)

    Larkin, A; Hystad, P

    2017-12-01

    We present a review of emerging technologies and how these can transform personal air pollution exposure assessment and subsequent health research. Estimating personal air pollution exposures is currently split broadly into methods for modeling exposures for large populations versus measuring exposures for small populations. Air pollution sensors, smartphones, and air pollution models capitalizing on big/new data sources offer tremendous opportunity for unifying these approaches and improving long-term personal exposure prediction at scales needed for population-based research. A multi-disciplinary approach is needed to combine these technologies to not only estimate personal exposures for epidemiological research but also determine drivers of these exposures and new prevention opportunities. While available technologies can revolutionize air pollution exposure research, ethical, privacy, logistical, and data science challenges must be met before widespread implementations occur. Available technologies and related advances in data science can improve long-term personal air pollution exposure estimates at scales needed for population-based research. This will advance our ability to evaluate the impacts of air pollution on human health and develop effective prevention strategies.

  14. Determinants of personal exposure to ozone in school children. Results from a panel study in Greece.

    Science.gov (United States)

    Dimakopoulou, Konstantina; Grivas, Georgios; Samoli, Evangelia; Rodopoulou, Sophia; Spyratos, Dionisis; Papakosta, Despoina; Karakatsani, Anna; Chaloulakou, Archontoula; Katsouyanni, Klea

    2017-04-01

    In the wider framework of the RESPOZE (ReSPiratory effects of OZone Exposure in Greek children) panel study, we investigated possible determinants of O 3 exposure of school children, measured with personal passive samplers, in Athens and Thessaloniki, Greece. Personal exposure to O 3 was measured for five weeks spread along the academic year 2013-14, in 186 school children in Athens and Thessaloniki, Greece. At the same time, at-school outdoor measurements were performed and ambient levels of 8-h daily maximum O 3 from fixed sites were collected. We also collected information on lifestyle and housing characteristics through an extended general questionnaire (GQ) and each participant completed daily time activity diaries (TADs) during the study period. Mean outdoor concentrations were higher during the warmer months, in the suburbs of the cities and in Athens. Personal exposure concentrations were significantly lower compared to outdoor. Daily levels of at-school outdoor and ambient levels of O 3 from fixed sites were significant determinants of personal exposure to O 3 . For a 10μg/m 3 increase in at-school outdoor O 3 concentrations and PM 10 measurements a 20.9% (95% CI: 13%, 28%) increase in personal exposure to O 3 was found. For a half an hour more spent in transportation an average increase of 7% (95% CI: 0.3%, 14.6%) in personal exposure to O 3 was observed. Among other possible determinants, time spent in transportation (TAD variable) and duration of open windows were the ones associated with personal O 3 exposure levels. Our results support the use of outdoor and ambient measurements from fixed sites in epidemiological studies as a proxy of personal exposure to O 3 , but this has to be calibrated taking into account personal measurements and time-activity patterns. Copyright © 2016 Elsevier Inc. All rights reserved.

  15. The effect of childhood trauma and Five-Factor Model personality traits on exposure to adult life events in patients with psychotic disorders.

    Science.gov (United States)

    Pos, Karin; Boyette, Lindy Lou; Meijer, Carin J; Koeter, Maarten; Krabbendam, Lydia; de Haan, Lieuwe; For Group

    2016-11-01

    Recent life events are associated with transition to and outcome in psychosis. Childhood trauma and personality characteristics play a role in proneness to adult life events. However, little is known about the relative contribution and interrelatedness of these characteristics in psychotic disorders. Therefore, we investigated whether Five-Factor Model (FFM) personality traits and childhood trauma (abuse and neglect) predict adult life events, and whether the effect of childhood trauma on life events is mediated by personality traits. One hundred and sixty-three patients with psychotic disorders were assessed at baseline on history of childhood maltreatment and FFM personality traits, and on recent life events at 3-year follow-up. Childhood abuse is associated with negative life events, and part of the effect of childhood abuse on negative life events is mediated by openness to experience. Openness to experience and extraversion are associated with more positive and negative life events. Childhood neglect and lower extraversion are related to experiencing less positive events. The association between childhood trauma and recent life events is partly mediated by personality. Future research could focus on mechanisms leading to positive life events, as positive life events may buffer against development of mental health problems.

  16. Personal exposure to volatile organic compounds in the Czech Republic

    Czech Academy of Sciences Publication Activity Database

    Švecová, Vlasta; Topinka, Jan; Solanský, I.; Rössner ml., Pavel; Šrám, Radim

    2012-01-01

    Roč. 22, č. 5 (2012), s. 455-460 ISSN 1559-0631 R&D Projects: GA MŽP(CZ) SP/1B3/8/08; GA MŠk 2B08005 Institutional research plan: CEZ:AV0Z50390703 Keywords : personal monitoring * personal exposure * air pollution Subject RIV: DN - Health Impact of the Environment Quality Impact factor: 3.187, year: 2012

  17. Personal exposure to Black Carbon in transport microenvironments

    Science.gov (United States)

    Dons, Evi; Int Panis, Luc; Van Poppel, Martine; Theunis, Jan; Wets, Geert

    2012-08-01

    We evaluated personal exposure of 62 individuals to the air pollutant Black Carbon, using 13 portable aethalometers while keeping detailed records of their time-activity pattern and whereabouts. Concentrations encountered in transport are studied in depth and related to trip motives. The evaluation comprises more than 1500 trips with different transport modes. Measurements were spread over two seasons. Results show that 6% of the time is spent in transport, but it accounts for 21% of personal exposure to Black Carbon and approximately 30% of inhaled dose. Concentrations in transport were 2-5 times higher compared to concentrations encountered at home. Exposure was highest for car drivers, and car and bus passengers. Concentrations of Black Carbon were only half as much when traveling by bike or on foot; when incorporating breathing rates, dose was found to be twice as high for active modes. Lowest 'in transport' concentrations were measured in trains, but nevertheless these concentrations are double the concentrations measured at home. Two thirds of the trips are car trips, and those trips showed a large spread in concentrations. In-car concentrations are higher during peak hours compared to off-peak, and are elevated on weekdays compared to Saturdays and even more so on Sundays. These findings result in significantly higher exposure during car commute trips (motive 'Work'), and lower concentrations for trips with motive 'Social and leisure'. Because of the many factors influencing exposure in transport, travel time is not a good predictor of integrated personal exposure or inhaled dose.

  18. Personality traits and combat exposure as predictors of psychopathology over time.

    Science.gov (United States)

    Koffel, E; Kramer, M D; Arbisi, P A; Erbes, C R; Kaler, M; Polusny, M A

    2016-01-01

    Research suggests that personality traits have both direct and indirect effects on the development of psychological symptoms, with indirect effects mediated by stressful or traumatic events. This study models the direct influence of personality traits on residualized changes in internalizing and externalizing symptoms following a stressful and potentially traumatic deployment, as well as the indirect influence of personality on symptom levels mediated by combat exposure. We utilized structural equation modeling with a longitudinal prospective study of 522 US National Guard soldiers deployed to Iraq. Analyses were based on self-report measures of personality, combat exposure, and internalizing and externalizing symptoms. Both pre-deployment Disconstraint and externalizing symptoms predicted combat exposure, which in turn predicted internalizing and externalizing symptoms. There was a significant indirect effect for pre-deployment externalizing symptoms on post-deployment externalizing via combat exposure (p personality on residualized changes in externalizing symptoms were found. Baseline symptom dimensions had significant direct and indirect effects on post-deployment symptoms. Controlling for both pre-exposure personality and symptoms, combat experiences remained positively related to both internalizing and externalizing symptoms. Implications for diagnostic classification are discussed.

  19. Tattoo Infections, Personal Resistance, and Contagious Exposure through Tattooing

    DEFF Research Database (Denmark)

    Serup, Jørgen

    2017-01-01

    of infection depends on the following triad: microbial pathogen and its aggressiveness, individual resistance of the tattooed, and inoculation and exposures by the tattoo needle and in the tattoo parlor. Some infectious risks can be controlled. Persons with weaknesses can refrain from tattooing. Tattoo parlors...

  20. Daily personal exposure to black carbon: A pilot study

    Science.gov (United States)

    Williams, Ryan D.; Knibbs, Luke D.

    2016-05-01

    Continuous personal monitoring is the benchmark for air pollution exposure assessment. Black carbon (BC) is a strong marker of primary combustion like vehicle and biomass emissions. There have been few studies that quantified daily personal BC exposure and the contribution that different microenvironments make to it. In this pilot study, we used a portable aethalometer to measure BC concentrations in an individual's breathing zone at 30-s intervals while he performed his usual daily activities. We used a GPS and time-activity diary to track where he spent his time. We performed twenty 24-h measurements, and observed an arithmetic mean daily exposure concentration of 603 ng/m3. We estimated that changing commute modes from bus to train reduced the 24-h mean BC exposure concentration by 29%. Switching from open windows to closed windows and recirculated air in a car led to a reduction of 32%. Living in a home without a wood-fired heater caused a reduction of 50% compared with a wood-heated home. Our preliminary findings highlight the potential utility of simple approaches to reduce a person's daily BC exposure.

  1. Field study of sound exposure by personal stereo

    DEFF Research Database (Denmark)

    Ordoñez, Rodrigo Pizarro; Reuter, Karen; Hammershøi, Dorte

    2006-01-01

    A number of large scale studies suggest that the exposure level used with personal stereo systems should raise concern. High levels can be produced by most commercially available mp3 players, and they are generally used in high background noise levels (i.e., while in a bus or rain). A field study...... on young people's habitual sound exposure to personal stereos has been carried out using a measurement method according to principles of ISO 11904-2:2004. Additionally the state of their hearing has also been assessed. This presentation deals with the methodological aspects relating to the quantification...... of habitual use, estimation of listening levels and exposure levels, and assessment of their state of hearing, by either threshold determination or OAE measurement, with a special view to the general validity of the results (uncertainty factors and their magnitude)....

  2. Experimental effects of exposure to pornography

    DEFF Research Database (Denmark)

    Hald, Gert Martin; Malamuth, Neil N

    2015-01-01

    Using a randomly selected community sample of 200 Danish young adult men and women in a randomized experimental design, the study investigated the effects of a personality trait (agreeableness), past pornography consumption, and experimental exposure to non-violent pornography on attitudes...... supporting violence against women (ASV). We found that lower levels of agreeableness and higher levels of past pornography consumption significantly predicted ASV. In addition, experimental exposure to pornography increased ASV but only among men low in agreeableness. This relationship was found...

  3. Effects from placental exposure

    Energy Technology Data Exchange (ETDEWEB)

    Kawamoto, S [Radiation Effect Research Foundation, Hiroshima (Japan)

    1975-12-01

    Investigations of the effects on the people who had received placental exposure at either Hiroshima or Nagasaki were discussed. All of the subjects were children who had been born at either Hiroshima or Nagasaki between noon of 31, May, 1946 and the atomic-bomb detornation. Deaths of embryos and neonates were determined by the radiation dosage and the growth phase of embryos. Bifid uvula and a slight decrease of number of lumbar vertebra were observed in 14 males and 3 females at Nagasaki. Mental deficiency occurred in 25% of the children whose mothers had received radiation at Nagasaki, and in 8% at Hiroshima. The occurrence of microcephaly was high at both places in the children who had received placental exposure of more than 150 rad. A significant retardation of growth was observed in those who had had a high radiation dosage. Congenitally abnormal persistence of pupillary membrane was very frequently observed in the group which had received a high dosage of radiation. Concerning progeria, mortality of infants under one year of age was increased in the group which had received a high dosage of radiation, but mortality statistics should continue to be observed.

  4. Pre-exposure prophylaxis for HIV-negative persons with partners living with HIV: uptake, use, and effectiveness in an open-label demonstration project in East Africa.

    Science.gov (United States)

    Heffron, Renee; Ngure, Kenneth; Odoyo, Josephine; Bulya, Nulu; Tindimwebwa, Edna; Hong, Ting; Kidoguchi, Lara; Donnell, Deborah; Mugo, Nelly R; Bukusi, Elizabeth A; Katabira, Elly; Asiimwe, Stephen; Morton, Jennifer; Morrison, Susan; Haugen, Harald; Mujugira, Andrew; Haberer, Jessica E; Ware, Norma C; Wyatt, Monique A; Marzinke, Mark A; Frenkel, Lisa M; Celum, Connie; Baeten, Jared M

    2017-11-06

    Introduction : Pre-exposure prophylaxis (PrEP) can provide high protection against HIV infection and is a recommended intervention for HIV-negative persons with substantial HIV risk, such as individuals with a partner living with HIV.  Demonstration projects of PrEP have been conducted in diverse settings worldwide to illustrate practical examples of how PrEP can be delivered.  Methods : We evaluated delivery of PrEP for HIV-negative partners within heterosexual HIV serodiscordant couples in an open-label demonstration project in East Africa.  The delivery model integrated PrEP into HIV treatment services, prioritizing PrEP for HIV-negative partners within serodiscordant couples prior to and during the first 6 months after the partner living with HIV initiated antiretroviral therapy (ART).  We measured adherence to PrEP through medication event monitoring system (MEMS) bottle caps and quantification of tenofovir in plasma among a random sample of participants. We estimated HIV infections prevented using a counterfactual cohort simulated from the placebo arm of a previous PrEP clinical trial. Results : We enrolled 1,010 HIV serodiscordant couples that were naïve to ART and PrEP.  Ninety-seven percent (97%) of HIV-negative partners initiated PrEP, and when PrEP was dispensed, objective measures suggest high adherence: 71% of HIV-negative participants took ≥80% of expected doses, as recorded via MEMS, and 81% of plasma samples had tenofovir detected.  A total of 4 incident HIV infections were observed (incidence rate=0.24 per 100 person-years), a 95% reduction (95% CI 86-98%, pproject for African HIV-negative individuals whose partners were known to be living with HIV.  Delivery of PrEP to HIV-negative partners within HIV serodiscordant couples was feasible and should be prioritized for wide-scale implementation.

  5. Personal exposure to wood dust among workers in NekaChoob factory in 2013

    Directory of Open Access Journals (Sweden)

    Mahmoud Mohammadyan

    2014-12-01

    Full Text Available Background and Purpose: Inhalation of hardwood dust may produce a range of adverse health effects in the upper and lower respiratory system, including asthma, along with Sino-nasal cancer and nasopharyngeal cancer. This study was carried out to evaluate personal exposure to wood dust among workers in chipboard and furniture production saloons in Neka Choob factory, Iran. Materials and Methods: Gravimetric method No. 0500 recommended by National Institute for Occupational Safety and Health was used to determine the wood dust concentrations in the workers’ breathing zone. The sampling air was drawn through a polyvinyl chloride filter within the breathing zone, using a calibrated personal sampling pump. Results: The mean workers’ personal exposure to wood dust in furniture production saloon (2.87 ± 1.95 mgm-3 was higher than mean exposure of workers whom were working in chipboard saloon (0.93 ± 0.35 mgm-3. The mean workers’ exposure to wood dust for both saloons was 1.70 ± 1.53 mgm-3. Conclusion: The mean workers’ personal exposure to wood dust in Neka Choob factory was higher than Occupational Exposure Limit (OEL recommended by national (Iranian Committee for Review and Collection of OEL and European ::union:: Scientific Committee on OEL committees. All workers in furniture production saloon and three workers in chipboard saloon have a mean exposure higher than OEL.

  6. Contribution of various microenvironments to the daily personal exposure to ultrafine particles

    DEFF Research Database (Denmark)

    Bekö, Gabriel; Kjeldsen, Birthe Uldahl; Olsen, Yulia

    2015-01-01

    a backpack equipped with a portable monitor, continuously recording particle number concentrations (PN), in order to measure the real-time individual exposure over a period of similar to 48 h. A GPS logger was carried along with the particle monitor and allowed us to estimate the contribution of UFP exposure......, compared to the GPS. These results may indicate limitations of using diaries, but also possible inaccuracy and miss-classification in the GPS data. (C) 2015 Elsevier Ltd. All rights reserved.......Exposure to ultrafine particles (UFP) may have adverse health effects. Central monitoring stations do not represent the personal exposure to UFP accurately. Few studies have previously focused on personal exposure to UFP. Sixty non-smoking residents living in Copenhagen, Denmark were asked to carry...

  7. Modeling personal particle-bound polycyclic aromatic hydrocarbon (pb-pah) exposure in human subjects in Southern California.

    Science.gov (United States)

    Wu, Jun; Tjoa, Thomas; Li, Lianfa; Jaimes, Guillermo; Delfino, Ralph J

    2012-07-11

    Exposure to polycyclic aromatic hydrocarbon (PAH) has been linked to various adverse health outcomes. Personal PAH exposures are usually measured by personal monitoring or biomarkers, which are costly and impractical for a large population. Modeling is a cost-effective alternative to characterize personal PAH exposure although challenges exist because the PAH exposure can be highly variable between locations and individuals in non-occupational settings. In this study we developed models to estimate personal inhalation exposures to particle-bound PAH (PB-PAH) using data from global positioning system (GPS) time-activity tracking data, traffic activity, and questionnaire information. We conducted real-time (1-min interval) personal PB-PAH exposure sampling coupled with GPS tracking in 28 non-smoking women for one to three sessions and one to nine days each session from August 2009 to November 2010 in Los Angeles and Orange Counties, California. Each subject filled out a baseline questionnaire and environmental and behavior questionnaires on their typical activities in the previous three months. A validated model was used to classify major time-activity patterns (indoor, in-vehicle, and other) based on the raw GPS data. Multiple-linear regression and mixed effect models were developed to estimate averaged daily and subject-level PB-PAH exposures. The covariates we examined included day of week and time of day, GPS-based time-activity and GPS speed, traffic- and roadway-related parameters, meteorological variables (i.e. temperature, wind speed, relative humidity), and socio-demographic variables and occupational exposures from the questionnaire. We measured personal PB-PAH exposures for 180 days with more than 6 h of valid data on each day. The adjusted R2 of the model was 0.58 for personal daily exposures, 0.61 for subject-level personal exposures, and 0.75 for subject-level micro-environmental exposures. The amount of time in vehicle (averaging 4.5% of total

  8. Development of personnel exposure management system with personal computer

    International Nuclear Information System (INIS)

    Yamato, Ichiro; Yamamoto, Toshiki

    1992-01-01

    In nuclear power plants, large scale personnel exposure management systems have been developed and established by utilities. Though being common in the base, the implementations are specific by plants. Contractors must control their workers' exposures by their own methods and systems. To comply with the utilities' parental systems, contractors' systems tend to differ by plants, thus make it difficult for contractors to design a standard system that is common to all relevant plants. Circumstances being as such, however, we have developed a system which is applicable to various customer utilities with minimal variations, using personal computers with database management and data communication softwares, with relatively low cost. We hope that this system will develop to the standard model for all Japanese contractors' personnel exposure management systems. (author)

  9. Correlates and consequences of exposure to video game violence: hostile personality, empathy, and aggressive behavior.

    Science.gov (United States)

    Bartholow, Bruce D; Sestir, Marc A; Davis, Edward B

    2005-11-01

    Research has shown that exposure to violent video games causes increases in aggression, but the mechanisms of this effect have remained elusive. Also, potential differences in short-term and long-term exposure are not well understood. An initial correlational study shows that video game violence exposure (VVE) is positively correlated with self-reports of aggressive behavior and that this relation is robust to controlling for multiple aspects of personality. A lab experiment showed that individuals low in VVE behave more aggressively after playing a violent video game than after a nonviolent game but that those high in VVE display relatively high levels of aggression regardless of game content. Mediational analyses show that trait hostility, empathy, and hostile perceptions partially account for the VVE effect on aggression. These findings suggest that repeated exposure to video game violence increases aggressive behavior in part via changes in cognitive and personality factors associated with desensitization.

  10. Personal exposure to inhalable cement dust among construction workers

    International Nuclear Information System (INIS)

    Peters, Susan; Kromhout, Hans; Thomassen, Yngvar; Fechter-Rink, Edeltraud

    2009-01-01

    A case study was carried out in 2006-2007 to assess the actual cement dust exposure among construction workers involved in a full-scale construction project and as a comparison among workers involved in various stages of cement and concrete production. Full-shift personal exposure measurements were performed for several job types. Inhalable dust and cement dust (based on analysis of elemental calcium) concentrations were determined. Inhalable dust exposures at the construction site ranged from 0.05 to 34 mg/m3, with a mean concentration of 1.0 mg/m3. For inhalable cement dust mean exposure was 0.3 mg/m3 (range 0.02-17 mg/m3). Reinforcement and pouring workers had the lowest average concentrations. Inhalable dust levels in the ready-mix and pre-cast concrete plants were, on average, below 0.5 mg/m3 for inhalable dust and below 0.2 mg/m3 for inhalable cement dust. Highest dust concentrations were measured in cement production, particularly during cleaning tasks (inhalable dust GM=55 mg/m3; inhalable cement dust GM=33 mg/m3) at which point the workers wore personal protective equipment. Elemental measurements showed highest but very variable cement percentages in the cement plant and very low percentages of cement during reinforcement work and pouring.

  11. Personal exposure to inhalable cement dust among construction workers.

    Science.gov (United States)

    Peters, Susan; Thomassen, Yngvar; Fechter-Rink, Edeltraud; Kromhout, Hans

    2009-01-01

    Objective- A case study was carried out to assess cement dust exposure and its determinants among construction workers and for comparison among workers in cement and concrete production.Methods- Full-shift personal exposure measurements were performed and samples were analysed for inhalable dust and its cement content. Exposure variability was modelled with linear mixed models.Results- Inhalable dust concentrations at the construction site ranged from 0.05 to 34 mg/m(3), with a mean of 1.0 mg/m(3). Average concentration for inhalable cement dust was 0.3 mg/m(3) (GM; range 0.02-17 mg/m(3)). Levels in the ready-mix and pre-cast concrete plants were on average 0.5 mg/m(3) (GM) for inhalable dust and 0.2 mg/m(3) (GM) for inhalable cement dust. Highest concentrations were measured in cement production, particularly during cleaning tasks (inhalable dust GM = 55 mg/m(3); inhalable cement dust GM = 33 mg/m(3)) at which point the workers wore personal protective equipment. Elemental measurements showed highest but very variable cement percentages in the cement plant and very low percentages during reinforcement work and pouring. Most likely other sources were contributing to dust concentrations, particularly at the construction site. Within job groups, temporal variability in exposure concentrations generally outweighed differences in average concentrations between workers. 'Using a broom', 'outdoor wind speed' and 'presence of rain' were overall the most influential factors affecting inhalable (cement) dust exposure.Conclusion- Job type appeared to be the main predictor of exposure to inhalable (cement) dust at the construction site. Inhalable dust concentrations in cement production plants, especially during cleaning tasks, are usually considerably higher than at the construction site.

  12. Elevated personal exposure to particulate matter from human activities in a residence.

    Science.gov (United States)

    Ferro, Andrea R; Kopperud, Royal J; Hildemann, Lynn M

    2004-01-01

    Continuous laser particle counters collocated with time-integrated filter samplers were used to measure personal, indoor, and outdoor particulate matter (PM) concentrations for a variety of prescribed human activities during a 5-day experimental period in a home in Redwood City, CA, USA. The mean daytime personal exposures to PM(2.5) and PM(5) during prescribed activities were 6 and 17 times, respectively, as high as the pre-activity indoor background concentration. Activities that resulted in the highest exposures of PM(2.5), PM(5), and PM(10) were those that disturbed dust reservoirs on furniture and textiles, such as dry dusting, folding clothes and blankets, and making a bed. The vigor of activity and type of flooring were also important factors for dust resuspension. Personal exposures to PM(2.5) and PM(5) were 1.4 and 1.6 times, respectively, as high as the indoor concentration as measured by a stationary monitor. The ratio of personal exposure to the indoor concentration was a function of both particle size and the distance of the human activity from the stationary indoor monitor. The results demonstrate that a wide variety of indoor human resuspension activities increase human exposure to PM and contribute to the "personal cloud" effect.

  13. Characterizing relationships between personal exposures to VOCs and socioeconomic, demographic, behavioral variables

    Science.gov (United States)

    Wang, Sheng-Wei; Majeed, Mohammed A.; Chu, Pei-Ling; Lin, Hui-Chih

    Socioeconomic and demographic factors have been found to significantly affect time-activity patterns in population cohorts that can subsequently influence personal exposures to air pollutants. This study investigates relationships between personal exposures to eight VOCs (benzene, toluene, ethylbenzene, o-xylene, m-,p-xylene, chloroform, 1,4-dichlorobenzene, and tetrachloroethene) and socioeconomic, demographic, time-activity pattern factors using data collected from the 1999-2000 National Health and Nutrition Examination Survey (NHANES) VOC study. Socio-demographic factors (such as race/ethnicity and family income) were generally found to significantly influence personal exposures to the three chlorinated compounds. This was mainly due to the associations paired by race/ethnicity and urban residence, race/ethnicity and use of air freshener in car, family income and use of dry-cleaner, which can in turn affect exposures to chloroform, 1,4-dichlorobenzene, and tetrachloroethene, respectively. For BTEX, the traffic-related compounds, housing characteristics (leaving home windows open and having an attached garage) and personal activities related to the uses of fuels or solvent-related products played more significant roles in influencing exposures. Significant differences in BTEX exposures were also commonly found in relation to gender, due to associated significant differences in time spent at work/school and outdoors. The coupling of Classification and Regression Tree (CART) and Bootstrap Aggregating (Bagging) techniques were used as effective tools for characterizing robust sets of significant VOC exposure factors presented above, which conventional statistical approaches could not accomplish. Identification of these significant VOC exposure factors can be used to generate hypotheses for future investigations about possible significant VOC exposure sources and pathways in the general U.S. population.

  14. Personal carbon monoxide exposures of preschool children in Helsinki, Finland: levels and determinants

    Science.gov (United States)

    Alm, S.; Mukala, K.; Jantunen, M. J.

    Personal CO exposures of 194 preschool children were measured with personal exposure monitors during a 24 week sampling period from fall 1990 to spring 1991 in Helsinki, Finland. Arithmetic mean of the maximum 1 and 8 h exposure levels were 6.0 and 3.3 mg m -3. The then Finnish ambient air quality guideline values for 1/8 h maximum CO level (30/10 mg m -3) were exceeded in 2/4% of the children's daily maximum 1/8 h exposure levels. Gas stove at home, parents, especially mother, smoking in the home, and living in high rise buildings — reflecting higher local population and traffic density — increased the children's CO exposures. The presence of a fireplace in the home was associated with decreased CO exposures. Father's high education reduced the children's CO exposure while mother's education level had no significant effect. The peak (15 min) exposure levels of the children commuting to day care center by car or bus were higher than those of the children who walked or came by bike.

  15. Human convective boundary layer and its impact on personal exposure

    DEFF Research Database (Denmark)

    Licina, Dusan

    generated by heat sources are gaining more prominent influence in space airflow formation and on the indoor environment overall. In such spaces with low air supply velocity, air mixing is minimized and the pollution emitted from localized indoor sources is non-uniformly distributed. The large spatial......People spend most of their time indoors and they are constantly exposed to pollution that affects their health, comfort and productivity. Due to strong economic and environmental pressures to reduce building energy consumption, low air velocity design is gaining popularity; hence buoyancy flows...... in inaccurate exposure prediction. This highlights the importance of a detailed understanding of the complex air movements that take place in the vicinity of the human body and their impact on personal exposure. The two objectives of the present work are: (i) to examine the extent to which the room air...

  16. Personal exposures to airborne metals in London taxi drivers and office workers in 1995 and 1996

    Energy Technology Data Exchange (ETDEWEB)

    Pfeifer, G.D.; Lynam, D.R. [Air Conservation Department, Ethyl Corporation, 330 South Fourth Street, Richmond, VA (United States); Harrison, R.M. [The University of Birmingham, Environmental Health, School of Chemistry, Edgbaston, Birmingham (United Kingdom)

    1999-09-01

    In 1995, a petroleum marketer introduced a diesel fuel additive in the UK containing Mn as MMT (methylcyclopentadienyl manganese tricarbonyl). A small study of personal exposures to airborne Mn in London was conducted before and after introduction of the additive to identify any major impact of the additive on exposures. In 1995, personal exposures to Mn were measured in two groups, taxi drivers and office workers (10 subjects per group) for two consecutive 7-day periods. A similar study was carried out in 1996 to determine if exposures had changed. Samples were also analyzed for Ca, Al, Mg and Pb. In 1996, exposures to aerosol mass as total suspended particulates (TSP) and PM{sub 2.5} were measured in addition to the metals. Manganese exposures in this cohort did not increase as a result of introduction of the additive. However, a significant source of Mn exposure was discovered during the conduct of these tests. The mean exposure to Mn was higher among the office workers in both years than that of the taxi drivers. This was due to the fact that approximately half the office workers commuted via the underground railway system where airborne dust and metal concentrations are significantly elevated over those in the general environment. Similar results have been noted in other cities having underground rail systems. Exposure to Mn, Pb, Ca, and Mg were not significantly different between the 2 years. Taxi drivers had higher exposures than office workers to Mg and Pb in both years. Commuting via the underground also had a significant impact on exposures to TSP, PM{sub 2.5}, Al, and Ca, but had little effect on exposures to Mg. The aerosol in the underground was particularly enriched in Mn, approximately 10-fold, when compared to the aerosol in the general environment. There are several possible sources for this Mn, including mechanical wear of the steel wheels on the steel rails, vaporization of metal from sparking of the third rail, or brake wear.

  17. A statistical framework for the validation of a population exposure model based on personal exposure data

    Science.gov (United States)

    Rodriguez, Delphy; Valari, Myrto; Markakis, Konstantinos; Payan, Sébastien

    2016-04-01

    Currently, ambient pollutant concentrations at monitoring sites are routinely measured by local networks, such as AIRPARIF in Paris, France. Pollutant concentration fields are also simulated with regional-scale chemistry transport models such as CHIMERE (http://www.lmd.polytechnique.fr/chimere) under air-quality forecasting platforms (e.g. Prev'Air http://www.prevair.org) or research projects. These data may be combined with more or less sophisticated techniques to provide a fairly good representation of pollutant concentration spatial gradients over urban areas. Here we focus on human exposure to atmospheric contaminants. Based on census data on population dynamics and demographics, modeled outdoor concentrations and infiltration of outdoor air-pollution indoors we have developed a population exposure model for ozone and PM2.5. A critical challenge in the field of population exposure modeling is model validation since personal exposure data are expensive and therefore, rare. However, recent research has made low cost mobile sensors fairly common and therefore personal exposure data should become more and more accessible. In view of planned cohort field-campaigns where such data will be available over the Paris region, we propose in the present study a statistical framework that makes the comparison between modeled and measured exposures meaningful. Our ultimate goal is to evaluate the exposure model by comparing modeled exposures to monitor data. The scientific question we address here is how to downscale modeled data that are estimated on the county population scale at the individual scale which is appropriate to the available measurements. To assess this question we developed a Bayesian hierarchical framework that assimilates actual individual data into population statistics and updates the probability estimate.

  18. Photometrically measured continuous personal PM(2.5) exposure: levels and correlation to a gravimetric method.

    Science.gov (United States)

    Lanki, Timo; Alm, Sari; Ruuskanen, Juhani; Janssen, Nicole A H; Jantunen, Matti; Pekkanen, Juha

    2002-05-01

    There is evidence that hourly variations in exposure to airborne particulate matter (PM) may be associated with adverse health effects. Still there are only few published data on short-term levels of personal exposure to PM in community settings. The objectives of the study were to assess hourly and shorter-term variations in personal PM(2.5) exposure in Helsinki, Finland, and to compare results from portable photometers to simultaneously measured gravimetric concentrations. The effect of relative humidity on the photometric results was also evaluated. Personal PM(2.5) exposures of elderly persons were assessed for 24 h every second week, resulting in 308 successful measurements from 47 different subjects. Large changes in concentrations in minutes after cooking or changing microenvironment were seen. The median of daily 1-h maxima was over twice the median of 24-h averages. There was a strong significant association between the two means, which was not linear. Median (95th percentile) of the photometric 24-h concentrations was 12.1 (37.7) and of the 24-h gravimetric concentrations 9.2 (21.3) microg/m3. The correlation between the photometric and the gravimetric method was quite good (R2=0.86). Participants spent 94.1% of their time indoors or in a vehicle, where relative humidity is usually low and thus not likely to cause significant effects on photometric results. Even outdoors, the relative humidity had only modest effect on concentrations. Photometers are a promising method to explore the health effects of short-term variation in personal PM(2.5) exposure.

  19. Personal exposures of preschool children to carbon monoxide: roles of ambient air quality and gas stoves

    Energy Technology Data Exchange (ETDEWEB)

    Alm, S.; Reponen, A.; Mukala, K.; Pasanen, P.; Tuomisto, J.; Jantunen, M.J. (National Public Health Institute, Kuopio (Finland). Division of Environmental Health)

    1994-12-01

    Personal 1 h mean CO exposures of preschool children in two day care centers (Toolo and Vallila) in Helsinki were measured with continuously recording personal exposure monitors. In Vallila, the median CO exposure of children from homes with gas stoves was 2.0 mgm[sup -3], and with electric stoves, 0.9 mgm[sup -3]. In Tooloo, the corresponding values were 1.9 and 1.0 mgm[sup -3], respectively. The national ambient air quality guidelines for CO in Finland were exceeded in a few percent of the exposure measurements. The results were compared to fixed-site ambient air monitoring data and related to the presence of town-gas fired stoves in the children's homes. The results show that fixed-site ambient air monitors are of little value in predicting personal exposures of children or even their relative differences between areas. They also show that town-gas fired stoves may have a profound effect on the CO exposures of the children. 8 refs., 4 figs., 3 tabs.

  20. Personal monitoring in complex geometry of photon exposures

    International Nuclear Information System (INIS)

    Cunha, P.G.; Drexler, G.

    1996-01-01

    The ratio (effective dose, E) / (personal dose equivalent, Hp(10) ) was calculated for some scenarios set in broad parallel photon beams. Worker's irradiation condition are shown in which the number and locations of the individual monitor have to be carefully determined in order to avoid that the value of effective dose is underestimated

  1. Trends in Exposure to Chemicals in Personal Care and Consumer Products.

    Science.gov (United States)

    Calafat, Antonia M; Valentin-Blasini, Liza; Ye, Xiaoyun

    2015-12-01

    Synthetic organic chemicals can be used in personal care and consumer products. Data on potential human health effects of these chemicals are limited-sometimes even contradictory-but because several of these chemicals are toxic in experimental animals, alternative compounds are entering consumer markets. Nevertheless, limited information exists on consequent exposure trends to both the original chemicals and their replacements. Biomonitoring (measuring concentrations of chemicals or their metabolites in people) provides invaluable information for exposure assessment. We use phthalates and bisphenol A-known industrial chemicals-and organophosphate insecticides as case studies to show exposure trends to these chemicals and their replacements (e.g., other phthalates, non-phthalate plasticizers, various bisphenols, pyrethroid insecticides) among the US general population. We compare US trends to national trends from Canada and Germany. Exposure to the original compounds is still prevalent among these general populations, but exposures to alternative chemicals may be increasing.

  2. 19 CFR 148.42 - Personal effects.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Personal effects. 148.42 Section 148.42 Customs... (CONTINUED) PERSONAL DECLARATIONS AND EXEMPTIONS Exemptions for Nonresidents § 148.42 Personal effects. (a... adornment, toilet articles, and similar personal effects. “Similar personal effects” include all articles...

  3. Measuring personal exposure from 900MHz mobile phone base stations in Australia and Belgium using a novel personal distributed exposimeter

    NARCIS (Netherlands)

    Bhatt, Chhavi Raj; Thielens, Arno; Redmayne, Mary; Abramson, Michael J; Billah, Baki; Sim, Malcolm R; Vermeulen, Roel; Martens, Luc; Joseph, Wout; Benke, Geza

    2016-01-01

    The aims of this study were to: i) measure personal exposure in the Global System for Mobile communications (GSM) 900MHz downlink (DL) frequency band with two systems of exposimeters, a personal distributed exposimeter (PDE) and a pair of ExpoM-RFs, ii) compare the GSM 900MHz DL exposures across

  4. An Inexpensive High-Temporal Resolution Electronic Sun Journal for Monitoring Personal Day to Day Sun Exposure Patterns

    Directory of Open Access Journals (Sweden)

    Nathan J. Downs

    2017-11-01

    Full Text Available Exposure to natural sunlight, specifically solar ultraviolet (UV radiation contributes to lifetime risks of skin cancer, eye disease, and diseases associated with vitamin D insufficiency. Improved knowledge of personal sun exposure patterns can inform public health policy; and help target high-risk population groups. Subsequently, an extensive number of studies have been conducted to measure personal solar UV exposure in a variety of settings. Many of these studies, however, use digital or paper-based journals (self-reported volunteer recall, or employ cost prohibitive electronic UV dosimeters (that limit the size of sample populations, to estimate periods of exposure. A cost effective personal electronic sun journal (ESJ built from readily available infrared photodiodes is presented in this research. The ESJ can be used to complement traditional UV dosimeters that measure total biologically effective exposure by providing a time-stamped sun exposure record. The ESJ can be easily attached to clothing and data logged to personal devices (including fitness monitors or smartphones. The ESJ improves upon self-reported exposure recording and is a cost effective high-temporal resolution option for monitoring personal sun exposure behavior in large population studies.

  5. NEURODEVELOPMENTAL EFFECTS OF ENVIRONMENTAL EXPOSURES

    Science.gov (United States)

    Neurodevelopmental Effects of Environmental ExposuresSherry G. Selevan, Pauline Mendola, Deborah C. Rice (US EPA, Washington,DC) The nervous system starts development early in gestation and continues to develop through adolescence. Thus, critical windows of vuln...

  6. Effects after prenatal radiation exposures

    International Nuclear Information System (INIS)

    Streffer, C.

    2001-01-01

    The mammalian organism is highly radiosensitive during all prenatal developmental periods. For most effects a dose relationship with a threshold is observed. These threshold doses are generally above the exposures from medical diagnostic procedures. The quality and extent of radiation effects are very much dependent on the developmental stage during which an exposure takes place and on the radiation dose. An exposure during the preimplantation period will cause lethality. Malformations are usually induced after exposures during the major organogenesis. Growth retardation is also possible during the late organogenesis and foetal periods. The lower limits of threshold doses for these effects are in the range of 100 mGy. A radiation exposure during the early foetal period can lead to severe mental retardation and impairment of intelligence. There are very serious effects with radiation doses above 0.3 Gy. Carcinogenesis can apparently occur after radiation exposures during the total prenatal development period. The radiation risk factor up to now has not been clear, but it seems that it is in the range of risk factors for cancer that are observed after exposures during childhood. For radiation doses that are used in radiological diagnostics the risk is zero or very low. A termination of pregnancy after doses below 100 mGy should not be considered. (author)

  7. The effect of childhood trauma and Five-Factor Model personality traits on exposure to adult life events in patients with psychotic disorders

    NARCIS (Netherlands)

    Pos, Karin; Boyette, Lindy Lou; Meijer, Carin J.; Koeter, Maarten; Krabbendam, Lydia; de Haan, Lieuwe; for GROUP, GROUP; Bruggeman, Richard; Cahn, Wiepke; de Haan, Lieuwe; Kahn, René S.; Meijer, Carin J.; Myin-Germeys, Inez; van Os, Jim; Wiersma, Durk

    2016-01-01

    Introduction: Recent life events are associated with transition to and outcome in psychosis. Childhood trauma and personality characteristics play a role in proneness to adult life events. However, little is known about the relative contribution and interrelatedness of these characteristics in

  8. Comprehensive personal RF-EMF exposure map and its potential use in epidemiological studies.

    Science.gov (United States)

    Gonzalez-Rubio, Jesus; Najera, Alberto; Arribas, Enrique

    2016-08-01

    In recent years, numerous epidemiological studies, which deal with the potential effects of mobile phone antennas on health, have almost exclusively focused on their distance to mobile phone base stations. Although it is known that this is not the best approach to the problem, this situation occurs due to the numerous difficulties when determining the personal exposure to the radiofrequency electromagnetic fields (RF-EMF). However, due to the rise of personal exposimeters, the evolution of spatial statistics, the development of geographical information systems and the use of powerful software, new alternatives are available to deal with these epidemiological studies and thus overcome the aforementioned difficulties. Using these tools, this paper presents a lattice map of personal RF-EMF exposure from exterior mobile phone base stations, covering the entire 110 administrative regions in the city of Albacete (Spain). For this purpose, we used a personal exposimeter, Satimo EME Spy 140 model, performing measurements every 4s The exposimeter was located inside the plastic basket of a bicycle, whose versatility permitted the access to all the zones of the city. Once the exposure map was prepared, its relation with the known antenna locations was studied. The 64 mobile telephone antennas of the city were also georeferenced; the randomness of both variables (exposure and antennas) were studied by means of the Moran's I test. Results showed that the distribution of the antennas follows a grouped pattern (pbased on the mean exposure values to RF-EMF in these sections. The displayed map would permit the execution of more accurate epidemiological studies, since it would be possible to compare the exposure measurements with the incidence data of a disease. Copyright © 2016 Elsevier Inc. All rights reserved.

  9. Personal exposure to dust and endotoxin in Robusta and Arabica coffee processing factories in Tanzania.

    Science.gov (United States)

    Sakwari, Gloria; Mamuya, Simon H D; Bråtveit, Magne; Larsson, Lennart; Pehrson, Christina; Moen, Bente E

    2013-03-01

    Endotoxin exposure associated with organic dust exposure has been studied in several industries. Coffee cherries that are dried directly after harvest may differ in dust and endotoxin emissions to those that are peeled and washed before drying. The aim of this study was to measure personal total dust and endotoxin levels and to evaluate their determinants of exposure in coffee processing factories. Using Sidekick Casella pumps at a flow rate of 2l/min, total dust levels were measured in the workers' breathing zone throughout the shift. Endotoxin was analyzed using the kinetic chromogenic Limulus amebocyte lysate assay. Separate linear mixed-effects models were used to evaluate exposure determinants for dust and endotoxin. Total dust and endotoxin exposure were significantly higher in Robusta than in Arabica coffee factories (geometric mean 3.41 mg/m(3) and 10 800 EU/m(3) versus 2.10 mg/m(3) and 1400 EU/m(3), respectively). Dry pre-processed coffee and differences in work tasks explained 30% of the total variance for total dust and 71% of the variance for endotoxin exposure. High exposure in Robusta processing is associated with the dry pre-processing method used after harvest. Dust and endotoxin exposure is high, in particular when processing dry pre-processed coffee. Minimization of dust emissions and use of efficient dust exhaust systems are important to prevent the development of respiratory system impairment in workers.

  10. Design and application of a web-based real-time personal PM2.5 exposure monitoring system.

    Science.gov (United States)

    Sun, Qinghua; Zhuang, Jia; Du, Yanjun; Xu, Dandan; Li, Tiantian

    2018-06-15

    Growing demand from public health research for conduct large-scale epidemiological studies to explore health effect of PM 2.5 was well-documented. To address this need, we design a web-based real-time personal PM 2.5 exposure monitoring system (RPPM2.5 system) which can help researcher to get big data of personal PM 2.5 exposure with low-cost, low labor requirement, and low operating technical requirements. RPPM2.5 system can provide relative accurate real-time personal exposure data for individuals, researches, and decision maker. And this system has been used in a survey of PM 2.5 personal exposure level conducted in 5 cities of China and has provided mass of valuable data for epidemiological research. Copyright © 2018 Elsevier B.V. All rights reserved.

  11. Personal Effects and Vital Matters

    DEFF Research Database (Denmark)

    Klemp McLeod, Ann-Sophie

    compositions. The dual status of personal effects as both illusory surfaces and material possessions is explored in analytical discussions of satiric literature ranging from The Memoirs of the Extraordinary Life, Works and Discoveries of Martinus Scriblerus (1741) though Jonathan Swift’s dressing room poems...... Concerning Human Understanding (1689), Edward Young’s Conjectures on Original Composition (1758) are used as points of departure in uncovering the pressures exerted on unitary constructions proprietorship satiric versions of the aggregate self....

  12. Biological effects and hazards of radiation exposure

    International Nuclear Information System (INIS)

    Boas, J.F.; Solomon, S.B.

    1990-01-01

    Radiation induced carcinogenesis and mutagenesis form the main risk to health from exposure to low levels of radiation. This risk effects can be at least qualitatively understood by considering the effects of radiation on cell DNA. Whilst exposure to high levels of radiation results in a number of identifiable effects, exposure to low levels of radiation may result in effects which only manifest themselves after many years. Risk estimates for low levels of radiation have been derived on the basis of a number of assumptions. In the case of uranium mine workers a major hazard arises from the inhalation of radon daughters. Whilst the correlation between radon daughter exposure and lung cancer incidence is well established, the numerical value of the risk factor is the subject of controversy. ICRP 50 gives a value of 10 cases per 10 6 person-years at risk per WLM (range 5-15 x 10 -6 PYR -1 WLM -1 ). The effect of smoking on lung cancer incidence rates amongst miners is also controversial. Nevertheless, smoking by miners should be discouraged

  13. Personal endotoxin exposure in a panel study of school children with asthma

    Directory of Open Access Journals (Sweden)

    Tjoa Thomas

    2011-08-01

    Full Text Available Abstract Background Endotoxin exposure has been associated with asthma exacerbations and increased asthma prevalence. However, there is little data regarding personal exposure to endotoxin in children at risk, or the relation of personal endotoxin exposure to residential or ambient airborne endotoxin. The relation between personal endotoxin and personal air pollution exposures is also unknown. Methods We characterized personal endotoxin exposures in 45 school children with asthma ages 9-18 years using 376 repeated measurements from a PM2.5 active personal exposure monitor. We also assayed endotoxin in PM2.5 samples collected from ambient regional sites (N = 97 days and from a subset of 12 indoor and outdoor subject home sites (N = 109 and 111 days, respectively in Riverside and Whittier, California. Endotoxin was measured using the Limulus Amoebocyte Lysate kinetic chromogenic assay. At the same time, we measured personal, home and ambient exposure to PM2.5 mass, elemental carbon (EC, and organic carbon (OC. To assess exposure relations we used both rank correlations and mixed linear regression models, adjusted for personal temperature and relative humidity. Results We found small positive correlations of personal endotoxin with personal PM2.5 EC and OC, but not personal PM2.5 mass or stationary site air pollutant measurements. Outdoor home, indoor home and ambient endotoxin were moderately to strongly correlated with each other. However, in mixed models, personal endotoxin was not associated with indoor home or outdoor home endotoxin, but was associated with ambient endotoxin. Dog and cat ownership were significantly associated with increased personal but not indoor endotoxin. Conclusions Daily fixed site measurements of endotoxin in the home environment may not predict daily personal exposure, although a larger sample size may be needed to assess this. This conclusion is relevant to short-term exposures involved in the acute exacerbation of

  14. Temporal Variability of Daily Personal Magnetic Field Exposure Metrics in Pregnant Women

    OpenAIRE

    Lewis, Ryan C.; Evenson, Kelly R.; Savitz, David A.; Meeker, John D.

    2014-01-01

    Recent epidemiology studies of power-frequency magnetic fields and reproductive health have characterized exposures using data collected from personal exposure monitors over a single day, possibly resulting in exposure misclassification due to temporal variability in daily personal magnetic field exposure metrics, but relevant data in adults are limited. We assessed the temporal variability of daily central tendency (time-weighted average, median) and peak (upper percentiles, maximum) persona...

  15. Personal exposure to benzene and 1,3-butadiene during petroleum refinery turnarounds and work in the oil harbour.

    Science.gov (United States)

    Akerstrom, M; Almerud, P; Andersson, E M; Strandberg, B; Sallsten, G

    2016-11-01

    Petroleum refinery workers' exposure to the carcinogens benzene and 1,3-butadiene has decreased during normal operations. However, certain occupational groups or events at the refineries still involve a risk of higher exposures. The aim of this study was to examine the personal exposure to benzene and 1,3-butadiene at refinery turnarounds and during work in the oil harbour. Personal exposure measurements of benzene and 1,3-butadiene were taken during work shifts, with a priori assumed higher benzene exposure, using PerkinElmer diffusive samplers filled with Carbopack X. Mean exposure levels were calculated, and repeated exposure measurements, when available, were assessed using mixed effect models. Group and individual compliance with the Swedish occupational exposure limit (OEL) was tested for the different exposure groups. Mean benzene exposure levels for refinery workers during the three measured turnarounds were 150, 610 and 960 µg/m 3 , and mean exposures for oil harbour workers and sewage tanker drivers were 310 and 360 µg/m 3 , respectively. Higher exposures were associated with handling benzene-rich products. Most occupational groups did not comply with the Swedish OEL for benzene nor did the individuals within the groups. The exposure to 1,3-butadiene was very low, between Work within the petroleum refinery industry, with potential exposure to open product streams containing higher fractions of benzene, pose a risk of personal benzene exposures exceeding the OEL. Refinery workers performing these work tasks frequently, such as contractors, sewage tanker drivers and oil harbour workers, need to be identified and protected.

  16. Detailed characterization of welding fumes in personal exposure samples

    International Nuclear Information System (INIS)

    Quémerais, B; Mino, James; Amin, M R; Golshahi, H; Izadi, H

    2015-01-01

    The objective of the project was to develop a method allowing for detailed characterization of welding particles including particle number concentration, size distribution, surface chemistry and chemical composition of individual particles, as well as metal concentration of various welding fumes in personal exposure samples using regular sampling equipment. A sample strategy was developed to evaluate the variation of the collection methods on mass concentration. Samples were collected with various samplers and filters at two different locations using our collection system. The first location was using a robotic welding system while the second was manual welding. Collected samples were analysed for mass concentration using gravimetryand metal concentration using ICP/OES. More advanced analysis was performed on selected filters using X-Ray Photoelectron Spectroscopy to determine surface composition of the particles, and X-Ray Diffraction to determine chemical composition of the fumes. Results showed that the robotic system had a lot of variation in space when the collection system was located close to the weld. Collection efficiency was found to be quite variable depending upon the type of filter. As well, metal concentrations in blank filters were dependent upon the type of filter with MCE presenting with the highest blank values. Results obtained with the XRD and XPS systems showed that it was possible to analyse a small of powdered welding fume sample but results on filters were not conclusive. (paper)

  17. Highly sensitive detection of urinary cadmium to assess personal exposure

    Energy Technology Data Exchange (ETDEWEB)

    Argun, Avni A.; Banks, Ashley M.; Merlen, Gwendolynne; Tempelman, Linda A. [Giner, Inc., 89 Rumford Ave., Newton 02466, MA United States (United States); Becker, Michael F.; Schuelke, Thomas [Fraunhofer USA – CCL, 1449 Engineering Research Ct., East Lansing 48824, MI (United States); Dweik, Badawi M., E-mail: bdweik@ginerinc.com [Giner, Inc., 89 Rumford Ave., Newton 02466, MA United States (United States)

    2013-04-22

    Highlights: ► An electrochemical sensor capable of detecting cadmium at parts-per-billion levels in urine. ► A novel fabrication method for Boron-Doped Diamond (BDD) ultramicroelectrode (UME) arrays. ► Unique combination of BDD UME arrays and a differential pulse voltammetry algorithm. ► High sensitivity, high reproducibility, and very low noise levels. ► Opportunity for portable operation to assess on-site personal exposure. -- Abstract: A series of Boron-Doped Diamond (BDD) ultramicroelectrode arrays were fabricated and investigated for their performance as electrochemical sensors to detect trace level metals such as cadmium. The steady-state diffusion behavior of these sensors was validated using cyclic voltammetry followed by electrochemical detection of cadmium in water and in human urine to demonstrate high sensitivity (>200 μA ppb{sup −1} cm{sup −2}) and low background current (<4 nA). When an array of ultramicroelectrodes was positioned with optimal spacing, these BDD sensors showed a sigmoidal diffusion behavior. They also demonstrated high accuracy with linear dose dependence for quantification of cadmium in a certified reference river water sample from the U.S. National Institute of Standards and Technology (NIST) as well as in a human urine sample spiked with 0.25–1 ppb cadmium.

  18. Different relationships between personal exposure and ambient concentration by particle size.

    Science.gov (United States)

    Guak, Sooyoung; Lee, Kiyoung

    2018-04-06

    Ambient particulate matter (PM) concentrations at monitoring stations were often used as an indicator of population exposure to PM in epidemiological studies. The correlation between personal exposure and ambient concentrations of PM varied because of diverse time-activity patterns. The aim of this study was to determine the relationship between personal exposure and ambient concentrations of PM 10 and PM 2.5 with minimal impact of time-activity pattern on personal exposure. Performance of the MicroPEM, v3.2 was evaluated by collocation with central ambient air monitors for PM 10 and PM 2.5 . A field technician repeatedly conducted measurement of 24 h personal exposures to PM 10 and PM 2.5 with a fixed time-activity pattern of office worker over 26 days in Seoul, Korea. The relationship between the MicroPEM and the ambient air monitor showed good linearity. Personal exposure and ambient concentrations of PM 2.5 were highly correlated with a fixed time-activity pattern compared with PM 10 . The finding implied a high infiltration rate of PM 2.5 and low infiltration rate of PM 10 . The relationship between personal exposure and ambient concentrations of PM 10 and PM 2.5 was different for high level episodes. In the Asian dust episode, staying indoors could reduce personal exposure to PM 10 . However, personal exposure to PM 2.5 could not be reduced by staying indoors during the fine dust advisory episode.

  19. Modeling personal particle-bound polycyclic aromatic hydrocarbon (pb-pah exposure in human subjects in Southern California

    Directory of Open Access Journals (Sweden)

    Wu Jun

    2012-07-01

    Full Text Available Abstract Background Exposure to polycyclic aromatic hydrocarbon (PAH has been linked to various adverse health outcomes. Personal PAH exposures are usually measured by personal monitoring or biomarkers, which are costly and impractical for a large population. Modeling is a cost-effective alternative to characterize personal PAH exposure although challenges exist because the PAH exposure can be highly variable between locations and individuals in non-occupational settings. In this study we developed models to estimate personal inhalation exposures to particle-bound PAH (PB-PAH using data from global positioning system (GPS time-activity tracking data, traffic activity, and questionnaire information. Methods We conducted real-time (1-min interval personal PB-PAH exposure sampling coupled with GPS tracking in 28 non-smoking women for one to three sessions and one to nine days each session from August 2009 to November 2010 in Los Angeles and Orange Counties, California. Each subject filled out a baseline questionnaire and environmental and behavior questionnaires on their typical activities in the previous three months. A validated model was used to classify major time-activity patterns (indoor, in-vehicle, and other based on the raw GPS data. Multiple-linear regression and mixed effect models were developed to estimate averaged daily and subject-level PB-PAH exposures. The covariates we examined included day of week and time of day, GPS-based time-activity and GPS speed, traffic- and roadway-related parameters, meteorological variables (i.e. temperature, wind speed, relative humidity, and socio-demographic variables and occupational exposures from the questionnaire. Results We measured personal PB-PAH exposures for 180 days with more than 6 h of valid data on each day. The adjusted R2 of the model was 0.58 for personal daily exposures, 0.61 for subject-level personal exposures, and 0.75 for subject-level micro-environmental exposures. The amount

  20. Attentional Modulation of the Mere Exposure Effect

    Science.gov (United States)

    Yagi, Yoshihiko; Ikoma, Shinobu; Kikuchi, Tadashi

    2009-01-01

    The "mere exposure effect" refers to the phenomenon where previous exposures to stimuli increase participants' subsequent affective preference for those stimuli. This study explored the effect of selective attention on the mere exposure effect. The experiments manipulated the to-be-attended drawings in the exposure period (either red or green…

  1. Hepatitis B immunisation in persons not previously exposed to hepatitis B or with unknown exposure status

    DEFF Research Database (Denmark)

    Mathew, Joseph L; El Dib, Regina; Mathew, Preethy J

    2008-01-01

    The benefits and harms of hepatitis B vaccination in persons not previously exposed to hepatitis B infection or with unknown exposure status have not been established.......The benefits and harms of hepatitis B vaccination in persons not previously exposed to hepatitis B infection or with unknown exposure status have not been established....

  2. Tattoo Infections, Personal Resistance, and Contagious Exposure through Tattooing.

    Science.gov (United States)

    Serup, Jørgen

    2017-01-01

    Bacterial infection of tattoos remains a common complication. Pyogenic bacteria can cause infections shortly after the tattoo is made. Severity of infection varies from minor to major, ultimately with life-threatening septicemia. Viral infections may be introduced, i.e. HVB, HVC, and HIV. The risk of infection depends on the following triad: microbial pathogen and its aggressiveness, individual resistance of the tattooed, and inoculation and exposures by the tattoo needle and in the tattoo parlor. Some infectious risks can be controlled. Persons with weaknesses can refrain from tattooing. Tattoo parlors and tattooing can be hygienic and clean albeit not sterile; much has improved helped by hygiene guidelines of professional tattooists' organizations and through control instituted by local and national authorities. Tattoo inks remain a potential source of infection difficult to control in a low-priced competitive market operating over the Internet and across national borders. Ten percent of new inks are contaminated with bacteria pathogenic to humans, independent of a claim of 'sterility'. Known brands and established manufacturers are considered safer. Work is in progress aiming at common European standards for tattoo hygiene. Doctors have a role not only in treating tattoo infections but also in reporting cases to the competent authority in their country to support the monitoring of tattoo infections at any time, as an instrument for the authority to detect local outbreaks of tattoo infections early and prevent that new tattoo customers become infected. It is a potential risk of the future that new and very aggressive bacteria not seen in the past may unexpectedly show up in the tattoo scene. © 2017 S. Karger AG, Basel.

  3. Chemical characterization and sources of personal exposure to fine particulate matter in the general population of Guangzhou, China

    Science.gov (United States)

    Chen, Xiao-Cui; Jahn, Heiko J.; Engling, Guenter; Ward, Tony J.; Kraemer, Alexander; Ho, Kin-Fai; Hung-Lam Yim, Steve; Chan, Chuen-Yu

    2017-04-01

    Fine particulate matter pollution severely deteriorates the environmental conditions and negatively impacts human health in the Chinese megacity Guangzhou. Concurrent ambient and personal measurements of fine particulate matter (PM2.5) were conducted in Guangzhou, China. Personal-to-ambient (P-C) relationships of PM2.5 chemical components were determined and sources of personal PM2.5 exposure were evaluated using principal component analysis along with a mixed-effects model. Water-soluble inorganic ions (mainly secondary inorganic ions) and anhydrosugars exhibited median personal-to-ambient (P/C) ratios < 1 accompanied by strong P-C correlations, indicating that these constituents in personal PM2.5 were significantly affected by ambient sources. Conversely, elemental carbon (EC) and calcium (Ca2+) showed median P/C ratios greater than unity, which indicated that among subjects who spent a great amount of time indoors, aside from particles of ambient origin, individual's total exposure to PM2.5 includes contributions of non-ambient exposure while indoors and outdoors (e.g., local traffic, indoor sources, personal activities). SO42- displayed very low coefficient of divergence (COD) values coupled with strong P-C correlations, implying a uniform distribution of SO42- in the urban area of Guangzhou. EC, Ca2+, and levoglucosan were otherwise heterogeneously distributed across individuals in different districts. Regional air pollution (50.4 ± 0.9%), traffic-related particles (8.6 ± 0.7%), dust-related particles (5.8 ± 0.7%), and biomass burning emissions (2.0 ± 0.2%) were moderate to high positive sources of personal PM2.5 exposure in Guangzhou. The observed positive and significant contribution of Ca2+ to personal PM2.5 exposure, highlighting indoor sources and/or personal activities, were driving factors determining personal exposure to dust-related particles. Considerable discrepancies (COD values ranging from 0.42 to 0.50) were shown between ambient

  4. Personal exposures to VOC in the upper end of the distribution—relationships to indoor, outdoor and workplace concentrations

    Science.gov (United States)

    Edwards, Rufus D.; Schweizer, Christian; Jantunen, Matti; Lai, Hak Kan; Bayer-Oglesby, Lucy; Katsouyanni, Klea; Nieuwenhuijsen, Mark; Saarela, Kristiina; Sram, Radim; Künzli, Nino

    Evaluation of relationships between median residential indoor, indoor workplace and population exposures may obscure potential strategies for exposure reduction. Evaluation of participants with personal exposures above median levels in the EXPOLIS study in Athens, Helsinki, Oxford and Prague illustrated that these participants frequently showed a different relationship to indoor and workplace levels than that shown by the population median. Thus, prioritization of environments for control measures based on median exposures may exclude important areas where effectively focused control measures are possible, and may therefore have little impact on the highest and most harmful exposures. Further, personal exposures at the upper end of the distribution may exceed the US EPA inhalation reference concentration (Rfc), illustrated here using hexane, naphthalene and benzene. For example upper 90th percentile personal exposures to benzene in Athens and Prague were 64 and 27 μg m -3 with peak exposures of 217 and 38 μg m -3, respectively for non-ETS exposed participants relative to an Rfc of 30 μg m -3. Strategies to reduce exposures to individual compounds, therefore, may benefit from focus on the high end of the distribution to identify activities and behaviors that result in elevated exposures. Control strategies targeting activities that lead to exposures in the upper end of the distribution would reduce the variability associated with population median values by bringing the upper end of the exposure distribution closer to median values. Thus, compliance with health-based standards would be more protective of the higher exposed fraction of the population, in whom health effects would be more expected.

  5. Personal carbon monoxide exposures of preschool children in Helsinki, Finland - comparison to ambient air concentrations

    Energy Technology Data Exchange (ETDEWEB)

    Alm, S.; Mukala, K.; Tittanen, P.; Jantunen, M.J. [KTL National Public Health Institute, Kuopio (Finland). Dept. of Environmental Health

    2001-07-01

    The associations of personal carbon monoxide (CO) exposures with ambient air CO concentrations measured at fixed monitoring sites, were studied among 194 children aged 3-6yr in four downtown and four suburban day-care centers in Helsinki, Finland. Each child carried a personal CO exposure monitor between 1 and 4 times for a time period of between 20 and 24h. CO concentrations at two fixed monitoring sites were measured simultaneously. The CO concentrations measured at the fixed monitoring sites were usually lower (mean maximum 8-h concentration: 0.9 and 2.6mgm{sup -3}) than the personal CO exposure concentrations (mean maximum 8-h concentration: 3.3mgm{sup -3}).The fixed site CO concentrations were poor predictors of the personal CO exposure concentrations. However, the correlations between the personal CO exposure and the fixed monitoring site CO concentrations increased (-0.03 -- -0.12 to 0.13-0.16) with increasing averaging times from 1 to 8h. Also, the fixed monitoring site CO concentrations explained the mean daily or weekly personal CO exposures of a group of simultaneously measured children better than individual exposure CO concentrations. This study suggests that the short-term CO personal exposure of children cannot be meaningfully assessed using fixed monitoring sites. (author)

  6. Personal exposure to total suspended particulates of adolescents living in Vanderbijlpark, South Africa

    CSIR Research Space (South Africa)

    Terblanche, APS

    1995-06-01

    Full Text Available Personal monitoring of exposure to air pollution is becoming increasingly important in health studies as a method of characterizing total exposure. We monitored the exposure of 31 teenagers to total suspended particulates (TSP) over a 12-hour period...

  7. Predicting personal exposure to airborne carbonyls using residential measurements and time/activity data

    Science.gov (United States)

    Liu, Weili; Zhang, Junfeng (Jim); Korn, Leo R.; Zhang, Lin; Weisel, Clifford P.; Turpin, Barbara; Morandi, Maria; Stock, Tom; Colome, Steve

    As a part of the Relationships of Indoor, Outdoor, and Personal Air (RIOPA) study, 48 h integrated residential indoor, outdoor, and personal exposure concentrations of 10 carbonyls were simultaneously measured in 234 homes selected from three US cities using the Passive Aldehydes and Ketones Samplers (PAKS). In this paper, we examine the feasibility of using residential indoor concentrations to predict personal exposures to carbonyls. Based on paired t-tests, the means of indoor concentrations were not different from those of personal exposure concentrations for eight out of the 10 measured carbonyls, indicating indoor carbonyls concentrations, in general, well predicted the central tendency of personal exposure concentrations. In a linear regression model, indoor concentrations explained 47%, 55%, and 65% of personal exposure variance for formaldehyde, acetaldehyde, and hexaldehyde, respectively. The predictability of indoor concentrations on cross-individual variability in personal exposure for the other carbonyls was poorer, explainingexposure concentrations. It was found that activities related to driving a vehicle and performing yard work had significant impacts on personal exposures to a few carbonyls.

  8. Children's exposure assessment of radiofrequency fields: Comparison between spot and personal measurements.

    Science.gov (United States)

    Gallastegi, Mara; Huss, Anke; Santa-Marina, Loreto; Aurrekoetxea, Juan J; Guxens, Mònica; Birks, Laura Ellen; Ibarluzea, Jesús; Guerra, David; Röösli, Martin; Jiménez-Zabala, Ana

    2018-05-24

    Radiofrequency (RF) fields are widely used and, while it is still unknown whether children are more vulnerable to this type of exposure, it is essential to explore their level of exposure in order to conduct adequate epidemiological studies. Personal measurements provide individualized information, but they are costly in terms of time and resources, especially in large epidemiological studies. Other approaches, such as estimation of time-weighted averages (TWAs) based on spot measurements could simplify the work. The aims of this study were to assess RF exposure in the Spanish INMA birth cohort by spot measurements and by personal measurements in the settings where children tend to spend most of their time, i.e., homes, schools and parks; to identify the settings and sources that contribute most to that exposure; and to explore if exposure assessment based on spot measurements is a valid proxy for personal exposure. When children were 8 years old, spot measurements were conducted in the principal settings of 104 participants: homes (104), schools and their playgrounds (26) and parks (79). At the same time, personal measurements were taken for a subsample of 50 children during 3 days. Exposure assessment based on personal and on spot measurements were compared both in terms of mean exposures and in exposure-dependent categories by means of Bland-Altman plots, Cohen's kappa and McNemar test. Median exposure levels ranged from 29.73 (in children's bedrooms) to 200.10 μW/m 2 (in school playgrounds) for spot measurements and were higher outdoors than indoors. Median personal exposure was 52.13 μW/m 2 and median levels of assessments based on spot measurements ranged from 25.46 to 123.21 μW/m 2 . Based on spot measurements, the sources that contributed most to the exposure were FM radio, mobile phone downlink and Digital Video Broadcasting-Terrestrial, while indoor and personal sources contributed very little (altogether spot measurements, with the latter

  9. Personal Exposure to Mixtures of Volatile Organic Compounds: Modeling and Further Analysis of the RIOPA Data

    Science.gov (United States)

    Batterman, Stuart; Su, Feng-Chiao; Li, Shi; Mukherjee, Bhramar; Jia, Chunrong

    2015-01-01

    INTRODUCTION Emission sources of volatile organic compounds (VOCs) are numerous and widespread in both indoor and outdoor environments. Concentrations of VOCs indoors typically exceed outdoor levels, and most people spend nearly 90% of their time indoors. Thus, indoor sources generally contribute the majority of VOC exposures for most people. VOC exposure has been associated with a wide range of acute and chronic health effects; for example, asthma, respiratory diseases, liver and kidney dysfunction, neurologic impairment, and cancer. Although exposures to most VOCs for most persons fall below health-based guidelines, and long-term trends show decreases in ambient emissions and concentrations, a subset of individuals experience much higher exposures that exceed guidelines. Thus, exposure to VOCs remains an important environmental health concern. The present understanding of VOC exposures is incomplete. With the exception of a few compounds, concentration and especially exposure data are limited; and like other environmental data, VOC exposure data can show multiple modes, low and high extreme values, and sometimes a large portion of data below method detection limits (MDLs). Field data also show considerable spatial or interpersonal variability, and although evidence is limited, temporal variability seems high. These characteristics can complicate modeling and other analyses aimed at risk assessment, policy actions, and exposure management. In addition to these analytic and statistical issues, exposure typically occurs as a mixture, and mixture components may interact or jointly contribute to adverse effects. However most pollutant regulations, guidelines, and studies remain focused on single compounds, and thus may underestimate cumulative exposures and risks arising from coexposures. In addition, the composition of VOC mixtures has not been thoroughly investigated, and mixture components show varying and complex dependencies. Finally, although many factors are

  10. Evaluating methods for estimating space-time paths of individuals in calculating long-term personal exposure to air pollution

    Science.gov (United States)

    Schmitz, Oliver; Soenario, Ivan; Vaartjes, Ilonca; Strak, Maciek; Hoek, Gerard; Brunekreef, Bert; Dijst, Martin; Karssenberg, Derek

    2016-04-01

    Air pollution is one of the major concerns for human health. Associations between air pollution and health are often calculated using long-term (i.e. years to decades) information on personal exposure for each individual in a cohort. Personal exposure is the air pollution aggregated along the space-time path visited by an individual. As air pollution may vary considerably in space and time, for instance due to motorised traffic, the estimation of the spatio-temporal location of a persons' space-time path is important to identify the personal exposure. However, long term exposure is mostly calculated using the air pollution concentration at the x, y location of someone's home which does not consider that individuals are mobile (commuting, recreation, relocation). This assumption is often made as it is a major challenge to estimate space-time paths for all individuals in large cohorts, mostly because limited information on mobility of individuals is available. We address this issue by evaluating multiple approaches for the calculation of space-time paths, thereby estimating the personal exposure along these space-time paths with hyper resolution air pollution maps at national scale. This allows us to evaluate the effect of the space-time path and resulting personal exposure. Air pollution (e.g. NO2, PM10) was mapped for the entire Netherlands at a resolution of 5×5 m2 using the land use regression models developed in the European Study of Cohorts for Air Pollution Effects (ESCAPE, http://escapeproject.eu/) and the open source software PCRaster (http://www.pcraster.eu). The models use predictor variables like population density, land use, and traffic related data sets, and are able to model spatial variation and within-city variability of annual average concentration values. We approximated space-time paths for all individuals in a cohort using various aggregations, including those representing space-time paths as the outline of a persons' home or associated parcel

  11. Measuring personal exposure from 900MHz mobile phone base stations in Australia and Belgium using a novel personal distributed exposimeter.

    Science.gov (United States)

    Bhatt, Chhavi Raj; Thielens, Arno; Redmayne, Mary; Abramson, Michael J; Billah, Baki; Sim, Malcolm R; Vermeulen, Roel; Martens, Luc; Joseph, Wout; Benke, Geza

    2016-01-01

    The aims of this study were to: i) measure personal exposure in the Global System for Mobile communications (GSM) 900MHz downlink (DL) frequency band with two systems of exposimeters, a personal distributed exposimeter (PDE) and a pair of ExpoM-RFs, ii) compare the GSM 900MHz DL exposures across various microenvironments in Australia and Belgium, and iii) evaluate the correlation between the PDE and ExpoM-RFs measurements. Personal exposure data were collected using the PDE and two ExpoM-RFs simultaneously across 34 microenvironments (17 each in Australia and Belgium) located in urban, suburban and rural areas. Summary statistics of the electric field strengths (V/m) were computed and compared across similar microenvironments in Australia and Belgium. The personal exposures across urban microenvironments were higher than those in the rural or suburban microenvironments. Likewise, the exposure levels across the outdoor were higher than those for indoor microenvironments. The five highest median exposure levels were: city centre (0.248V/m), bus (0.124V/m), railway station (0.105V/m), mountain/forest (rural) (0.057V/m), and train (0.055V/m) [Australia]; and bicycle (urban) (0.238V/m), tram station (0.238V/m), city centre (0.156V/m), residential outdoor (urban) (0.139V/m) and park (0.124V/m) [Belgium]. Exposures in the GSM900 MHz frequency band across most of the microenvironments in Australia were significantly lower than the exposures across the microenvironments in Belgium. Overall correlations between the PDE and the ExpoM-RFs measurements were high. The measured exposure levels were far below the general public reference levels recommended in the guidelines of the ICNIRP and the ARPANSA. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. Comparison of particulate matter exposure estimates in young children from personal sampling equipment and a robotic sampler.

    Science.gov (United States)

    Sagona, Jessica A; Shalat, Stuart L; Wang, Zuocheng; Ramagopal, Maya; Black, Kathleen; Hernandez, Marta; Mainelis, Gediminas

    2017-05-01

    Accurate characterization of particulate matter (PM) exposure in young children is difficult, because personal samplers are often too heavy, bulky or impractical to be used. The Pretoddler Inhalable Particulate Environmental Robotic (PIPER) sampler was developed to help address this problem. In this study, we measured inhalable PM exposures in 2-year-olds via a lightweight personal sampler worn in a small backpack and evaluated the use of a robotic sampler with an identical sampling train for estimating PM exposure in this age group. PM mass concentrations measured by the personal sampler ranged from 100 to almost 1,200 μg/m 3 , with a median value of 331 μg/m 3 . PM concentrations measured by PIPER were considerably lower, ranging from 14 to 513 μg/m 3 with a median value of 56 μg/m 3 . Floor cleaning habits and activity patterns of the 2-year-olds varied widely by home; vigorous play and recent floor cleaning were most associated with higher personal exposure. Our findings highlight the need for additional characterization of children's activity patterns and their effect on personal exposures.

  13. Does cultural exposure partially explain the association between personality and political orientation?

    Science.gov (United States)

    Xu, Xiaowen; Mar, Raymond A; Peterson, Jordan B

    2013-11-01

    Differences in political orientation are partly rooted in personality, with liberalism predicted by Openness to Experience and conservatism by Conscientiousness. Since Openness is positively associated with intellectual and creative activities, these may help shape political orientation. We examined whether exposure to cultural activities and historical knowledge mediates the relationship between personality and political orientation. Specifically, we examined the mediational role of print exposure (Study 1), film exposure (Study 2), and knowledge of American history (Study 3). Studies 1 and 2 found that print and film exposure mediated the relationships Openness to Experience and Conscientiousness have with political orientation. In Study 3, knowledge of American history mediated the relationship between Openness and political orientation, but not the association between Conscientiousness and political orientation. Exposure to culture, and a corollary of this exposure in the form of acquiring knowledge, can therefore partially explain the associations between personality and political orientation.

  14. Aggregate consumer exposure to UV filter ethylhexyl methoxycinnamate via personal care products.

    Science.gov (United States)

    Manová, Eva; von Goetz, Natalie; Hungerbuehler, Konrad

    2015-01-01

    Ultraviolet (UV) filters are substances designed to protect our skin from UV-induced damage and can be found in many categories of personal care products (PCPs). The potential endocrine-disrupting effects attributed to UV filter ethylhexyl methoxycinnamate (EHMC) are being debated. We evaluated the aggregate exposure of the Swiss-German population (N=1196; ages ≤1-97years) to EHMC via the use of PCPs; thus we provide the first comprehensive information about the current EHMC exposure sources and aggregate exposure levels. In our probabilistic modeling method performed at an individual level, PCP use data obtained by a postal questionnaire were linked to concentration data on EHMC gained from chemical analyses of PCPs used by the questionnaire respondents. The modeled median and 99.9th percentile of the internal aggregate exposure for the general population were 0.012 and 0.873mgday(-1)kg(-1) and 0.008 and 0.122mgday(-1)kg(-1) for the summer/autumn and winter/spring period, respectively. The major contributors to internal aggregate exposure were sunscreen products in summer/autumn (females: 64%; males: 85%; children aged ≤12years 93%). In winter/spring, lip care dominated for females (30%) and sunscreen for males (38%) and children aged ≤12years (50%). Overall, the internal aggregate exposure estimates for the studied population are shown to be below the Derived No Effect Level (DNEL) for EHMC i.e., the level of exposure above which humans should not be exposed; however, when an intense short-term exposure via sunscreen is accounted for during a sunbathing day, at the high-end percentiles (99.9th) the predicted aggregate exposure exceeds the DNEL for thyroid-disrupting effects such as for children aged ≤4years, who might be particularly susceptible to endocrine disrupting events. It is nevertheless critical to acknowledge that quantitative data on transdermal penetration of EHMC from PCPs are currently insufficient. Since long-term effects of endocrine

  15. Health Effects of Exposures to Mercury

    Science.gov (United States)

    ... IRIS database Top of Page Elemental (Metallic) Mercury Effects Exposures to metallic mercury most often occur when metallic ... poor performance on tests of mental function Higher exposures may also cause kidney effects, respiratory failure and death. Note that metallic mercury ...

  16. Dispersal of Exhaled Air and Personal Exposure in Displacement Ventilated Rooms

    DEFF Research Database (Denmark)

    Bjørn, Erik; Nielsen, Peter Vilhelm

    2002-01-01

    The influence of the human exhalation on flow fields, contaminant distributions, and personal exposures in displacement ventilated rooms is studied together with the effects of physical movement. Experiments are conducted in full-scale test rooms with life-sized breathing thermal manikins....... Numerical simulations support the experiments. Air exhaled through the mouth can lock in a thermally stratified layer, if the vertical temperature gradient in breathing zone height is sufficiently large. With exhalation through the nose, exhaled air flows to the upper part of the room. The exhalation flow...

  17. Comparison of personal radio frequency electromagnetic field exposure in different urban areas across Europe

    International Nuclear Information System (INIS)

    Joseph, Wout; Frei, Patrizia; Rooesli, Martin; Thuroczy, Gyoergy; Gajsek, Peter; Trcek, Tomaz; Bolte, John; Vermeeren, Guenter; Mohler, Evelyn; Juhasz, Peter; Finta, Viktoria; Martens, Luc

    2010-01-01

    Background: Only limited data are available on personal radio frequency electromagnetic field (RF-EMF) exposure in everyday life. Several European countries performed measurement studies in this area of research. However, a comparison between countries regarding typical exposure levels is lacking. Objectives: To compare for the first time mean exposure levels and contributions of different sources in specific environments between different European countries. Methods: In five countries (Belgium, Switzerland, Slovenia, Hungary, and the Netherlands), measurement studies were performed using the same personal exposure meters. The pooled data were analyzed using the robust regression on order statistics (ROS) method in order to allow for data below the detection limit. Mean exposure levels were compared between different microenvironments such as homes, public transports, or outdoor. Results: Exposure levels were of the same order of magnitude in all countries and well below the international exposure limits. In all countries except for the Netherlands, the highest total exposure was measured in transport vehicles (trains, car, and busses), mainly due to radiation from mobile phone handsets (up to 97%). Exposure levels were in general lower in private houses or flats than in offices and outdoors. At home, contributions from various sources were quite different between countries. Conclusions: Highest total personal RF-EMF exposure was measured inside transport vehicles and was well below international exposure limits. This is mainly due to mobile phone handsets. Mobile telecommunication can be considered to be the main contribution to total RF-EMF exposure in all microenvironments.

  18. Chernobyl accident. Exposures and effects

    International Nuclear Information System (INIS)

    Bennett, B.; Bouville, A.; Hall, P.; Savkin, M.; Storm, H.

    2000-01-01

    from the disintegration of the former Soviet Union. The United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) has given particular attention to the accident. Estimates of average doses in separate regions of countries and for the population of the northern hemisphere as a whole were presented in Annex D of the UNSCEAR 1988 Report. The experience gained in treating the immediate radiation injuries of workers and fire fighters involved in controlling the accident were also reviewed in the UNSCEAR 1988 Report (Annex G). The UNSCEAR Committee is currently involved in the final phase of preparation of a further assessment of the exposures and effects of the accident. During the last several years, considerable attention has been devoted to investigating possible associations between health effects in the populations and the exposure to radionuclides released and dispersed following the Chernobyl accident. Of particular note has been the occurrence of numerous thyroid cancers in children. The number of thyroid cancers in individuals exposed in childhood, particularly in the severely contaminated areas of Belarus, Russia, and Ukraine is considerably greater than expected based on previous knowledge. The high incidence and the short induction period have not been experienced in other populations, and other factors are most certainly influencing the risk. If the current trend continues, further thyroid cancers can be expected to occur, especially in those exposed at young ages. The most recent findings indicate that the thyroid cancer risk for those older than 10 years of age at the time of the accident is leveling off, while the increase continues for those younger than 4-5 years in 1986. Apart from the dramatic increase in thyroid cancer after childhood exposure, there is no evidence of a major public health impact 14 years after the Chernobyl accident. No increases in overall cancer incidence or mortality have been observed that could be attributed

  19. Epigenetic Effects of Cannabis Exposure

    Science.gov (United States)

    Szutorisz, Henrietta; Hurd, Yasmin L.

    2015-01-01

    The past decade has witnessed a number of societal and political changes that have raised critical questions about the long-term impact of marijuana (Cannabis sativa) that are especially important given the prevalence of its abuse and that potential long-term effects still largely lack scientific data. Disturbances of the epigenome have generally been hypothesized as the molecular machinery underlying the persistent, often tissue-specific transcriptional and behavioral effects of cannabinoids that have been observed within one’s lifetime and even into the subsequent generation. Here, we provide an overview of the current published scientific literature that examined epigenetic effects of cannabinoids. Though mechanistic insights about the epigenome remain sparse, accumulating data in humans and animal models have begun to reveal aberrant epigenetic modifications in brain and the periphery linked to cannabis exposure. Expansion of such knowledge and causal molecular relationships could help provide novel targets for future therapeutic interventions. PMID:26546076

  20. Predicting personal exposure of Windsor, Ontario residents to volatile organic compounds using indoor measurements and survey data

    Science.gov (United States)

    Stocco, Corinne; MacNeill, Morgan; Wang, Daniel; Xu, Xiaohong; Guay, Mireille; Brook, Jeff; Wheeler, Amanda J.

    As part of a multi-year personal exposure monitoring campaign, we collected personal, indoor, and outdoor levels of 188 volatile organic compounds (VOCs). In 2005, data were obtained for 48 non-smoking adults from Windsor, Ontario in order to assess their exposure to VOCs based on their daily routines and characteristics of their homes. During the 8-week winter and summer sampling sessions, five repeated 24-h measurements were obtained for each home. This paper focuses on the analysis of 18 VOCs: 11 have been declared toxic as defined under the Canadian Environmental Protection Act, [1999. Statutes of Canada. Act assented to September 14, 1999. Ottawa: Queen's Printer. Available at Canada Gazette (Part III) 22(3): (Chapter 33). http://canadagazette.gc.ca/partIII/1999/g3-02203.pdf], and seven are commonly found in household and personal care products. Results of mixed effects models indicate that personal exposure to these VOCs can be largely predicted by indoor concentrations, with models including indoor concentrations found to have an r2 value for the fixed effects ranging from 58.4% to 87.2% for the CEPA toxic VOCs and from 41.7% to 90.1% for the commonly found VOCs. Given that people spend the majority of their time inside their home, characteristics of the home such as air exchange rates, type of garage, and type of stove have a greater potential to impact personal exposures.

  1. Socioeconomic and personal behavioral factors affecting children's exposure to VOCs in urban areas in Korea.

    Science.gov (United States)

    Byun, Hyaejeong; Ryu, Kyongnam; Jang, Kyungjo; Bae, Hyunjoo; Kim, Dongjin; Shin, Hosung; Chu, Jangmin; Yoon, Chungsik

    2010-02-01

    Volatile organic compounds (VOCs) are known to cause adverse health effects. We investigated the relationships between children's VOC exposure and socioeconomic and human activity factors with passive personal samplers, questionnaires, and time-activity diaries (TAD). Statistical analyses were conducted using SAS 9.1, and the results were organized using SigmaPlot 8.0 software. Chemicals such as benzene, toluene, 2-butanone, ethylbenzene, xylene, chloroform, n-hexane, heptane, and some kinds of decanes, which are known to adversely affect public health, were identified in measured samples. These were mainly emitted from outdoor sources (e.g., vehicular traffic) or indoor sources (e.g., household activities such as cooking and cleaning) or both. We concluded that region was the most important socioeconomic factor affecting children's VOC exposure, and the significant compounds were n-hexane (p = 0.006), 1,1,1-trichloroethane (p = 0.001), benzene (p = 0.003), toluene (p = 0.002), ethylbenzene (p = 0.020), m-, p-xylene (p = 0.014), dodecane (p = 0.003), and hexadecane (p = 0.001). Parental education, year of home construction and type of housing were also slightly correlated with personal VOC exposure. Only the concentration of o-xylene (p = 0.027) was significantly affected by the parental education, and the concentrations of benzene (p = 0.030) and 2-butanone (p = 0.049) by the type of housing. Also, tridecane (p = 0.049) and n-hexane (p = 0.033) were significantly associated with the year of home construction. When household activities such as cooking were performed indoors, children's VOC concentrations tended to be higher, especially for n-hexane, chloroform, heptane, toluene (p factors simultaneously, socioeconomic factors such as region had a greater effect on children's VOC exposures than indoor activities. From this study, we can suggest that socioeconomic factors as well as environmental factors should be considered when formulating environmental policy to

  2. Time and Place as Modifiers of Personal UV Exposure

    Directory of Open Access Journals (Sweden)

    Brian L. Diffey

    2018-05-01

    Full Text Available It is a common belief that, if we want to limit our sun exposure during outdoor recreational activities and holidays in order to avoid sunburn or reduce our risk of skin cancer, we need to reach for the bottle of sunscreen or cover up with clothing. As important as these measures are, there is another way to enjoy our time outdoors and still benefit from the experience. In this article, we consider the impact of time, place, and behaviour outdoors on our exposure to solar ultraviolet (UV radiation. Some of the simple actions we can take in controlling our UV exposure include being aware of the position of the sun in the sky, understanding how we can use the UV index to guide our outdoor exposure, and the importance of reducing our sun exposure around the middle of the day. Finally we review our preferred holiday activities and destinations, and the influence of outdoor leisure pursuits. By planning where and when we spend our leisure time in the sun, we can maximise our enjoyment whilst limiting our UV exposure.

  3. Time and Place as Modifiers of Personal UV Exposure.

    Science.gov (United States)

    Diffey, Brian L

    2018-05-30

    It is a common belief that, if we want to limit our sun exposure during outdoor recreational activities and holidays in order to avoid sunburn or reduce our risk of skin cancer, we need to reach for the bottle of sunscreen or cover up with clothing. As important as these measures are, there is another way to enjoy our time outdoors and still benefit from the experience. In this article, we consider the impact of time, place, and behaviour outdoors on our exposure to solar ultraviolet (UV) radiation. Some of the simple actions we can take in controlling our UV exposure include being aware of the position of the sun in the sky, understanding how we can use the UV index to guide our outdoor exposure, and the importance of reducing our sun exposure around the middle of the day. Finally we review our preferred holiday activities and destinations, and the influence of outdoor leisure pursuits. By planning where and when we spend our leisure time in the sun, we can maximise our enjoyment whilst limiting our UV exposure.

  4. Inter-comparison of personal monitors for nanoparticles exposure at workplaces and in the environment.

    Science.gov (United States)

    Todea, Ana Maria; Beckmann, Stefanie; Kaminski, Heinz; Bard, Delphine; Bau, Sébastien; Clavaguera, Simon; Dahmann, Dirk; Dozol, Hélène; Dziurowitz, Nico; Elihn, Karine; Fierz, Martin; Lidén, Göran; Meyer-Plath, Asmus; Monz, Christian; Neumann, Volker; Pelzer, Johannes; Simonow, Barbara Katrin; Thali, Patrick; Tuinman, Ilse; van der Vleuten, Arjan; Vroomen, Huub; Asbach, Christof

    2017-12-15

    Personal monitors based on unipolar diffusion charging (miniDiSC/DiSCmini, NanoTracer, Partector) can be used to assess the individual exposure to nanoparticles in different environments. The charge acquired by the aerosol particles is nearly proportional to the particle diameter and, by coincidence, also nearly proportional to the alveolar lung-deposited surface area (LDSA), the metric reported by all three instruments. In addition, the miniDiSC/DiSCmini and the NanoTracer report particle number concentration and mean particle size. In view of their use for personal exposure studies, the comparability of these personal monitors was assessed in two measurement campaigns. Altogether 29 different polydisperse test aerosols were generated during the two campaigns, covering a large range of particle sizes, morphologies and concentrations. The data provided by the personal monitors were compared with those obtained from reference instruments: a scanning mobility particle sizer (SMPS) for LDSA and mean particle size and a ultrafine particle counter (UCPC) for number concentration. The results indicated that the LDSA concentrations and the mean particle sizes provided by all investigated instruments in this study were in the order of ±30% of the reference value obtained from the SMPS when the particle sizes of the test aerosols generated were within 20-400nm and the instruments were properly calibrated. Particle size, morphology and concentration did not have a major effect within the aforementioned limits. The comparability of the number concentrations was found to be slightly worse and in the range of ±50% of the reference value obtained from the UCPC. In addition, a minor effect of the particle morphology on the number concentration measurements was observed. The presence of particles >400nm can drastically bias the measurement results of all instruments and all metrics determined. Copyright © 2017 Elsevier B.V. All rights reserved.

  5. Attentional modulation of the mere exposure effect

    OpenAIRE

    Yagi, Yoshihiko; Ikoma, Shinobu; Kikuchi, Tadashi

    2009-01-01

    The mere exposure effect refers to the phenomenon where previous exposures to stimuli increase participants’ subsequent affective preference for those stimuli. This study explored the effect of selective attention on the mere exposure effect. The experiments manipulated the to-be-attended drawings in the exposure period (either red or green polygons in Experiments 1 and 2; both red and green polygons in Experiments 3 and 4) and black to-be-evaluated drawings in the affective judgment period (...

  6. Schoolyard Shade and Sun Exposure: Assessment of Personal Monitoring During Children's Physical Activity.

    Science.gov (United States)

    Vanos, Jennifer K; McKercher, Grant R; Naughton, Kylie; Lochbaum, Marc

    2017-07-01

    Childhood exposure to ultraviolet radiation (UVR) is a major risk factor for the development of melanoma later in life. However, it is challenging to accurately determine personal outdoor exposure to UVR, specifically erythemally weighted UVR (UV E ry ), due to technological constraints, variable time-activity patterns, and the influence of outdoor environmental design. To address this challenge, this study utilized mobile and stationary techniques to examine the UV E ry exposures of 14 children in a schoolyard in Lubbock, TX, in spring 2016. The aims of the study were to examine the influence of artificial shade on personal UV E ry exposures and to assess full sun exposure ratios (ERs) within the same playground microenvironment. On average, personal wrist dosimeters worn during play in the sun measured 18% of the total onsite UV E ry measured by a stationary UV pyranometer. Shade was found to significantly reduce the personal UV E ry exposures by 55%, UVB 280-315 nm exposures by 91%, and the overall solar radiation by 84%. Substantial benefits can be garnered through focused design of children's recreational space to utilize shade-both natural and artificial-to reduce UVR exposures during play, and to extend safe outdoor stays. Finally, although the wrist is a practical location for a dosimeter, it often underestimates full exposures, particularly during physical activity. © 2017 The American Society of Photobiology.

  7. Personal exposure to mixtures of volatile organic compounds: modeling and further analysis of the RIOPA data.

    Science.gov (United States)

    Batterman, Stuart; Su, Feng-Chiao; Li, Shi; Mukherjee, Bhramar; Jia, Chunrong

    2014-06-01

    Emission sources of volatile organic compounds (VOCs*) are numerous and widespread in both indoor and outdoor environments. Concentrations of VOCs indoors typically exceed outdoor levels, and most people spend nearly 90% of their time indoors. Thus, indoor sources generally contribute the majority of VOC exposures for most people. VOC exposure has been associated with a wide range of acute and chronic health effects; for example, asthma, respiratory diseases, liver and kidney dysfunction, neurologic impairment, and cancer. Although exposures to most VOCs for most persons fall below health-based guidelines, and long-term trends show decreases in ambient emissions and concentrations, a subset of individuals experience much higher exposures that exceed guidelines. Thus, exposure to VOCs remains an important environmental health concern. The present understanding of VOC exposures is incomplete. With the exception of a few compounds, concentration and especially exposure data are limited; and like other environmental data, VOC exposure data can show multiple modes, low and high extreme values, and sometimes a large portion of data below method detection limits (MDLs). Field data also show considerable spatial or interpersonal variability, and although evidence is limited, temporal variability seems high. These characteristics can complicate modeling and other analyses aimed at risk assessment, policy actions, and exposure management. In addition to these analytic and statistical issues, exposure typically occurs as a mixture, and mixture components may interact or jointly contribute to adverse effects. However most pollutant regulations, guidelines, and studies remain focused on single compounds, and thus may underestimate cumulative exposures and risks arising from coexposures. In addition, the composition of VOC mixtures has not been thoroughly investigated, and mixture components show varying and complex dependencies. Finally, although many factors are known to

  8. Microenvironmental characteristics important for personal exposures to aldehydes in Sacramento, CA, and Milwaukee, WI

    Science.gov (United States)

    Raymer, J. H.; Akland, G.; Johnson, T. R.; Long, T.; Michael, L.; Cauble, L.; McCombs, M.

    Oxygenated additives in gasoline are designed to decrease the ozone-forming hydrocarbons and total air toxics, yet they can increase the emissions of aldehydes and thus increase human exposure to these toxic compounds. This paper describes a study conducted to characterize targeted aldehydes in microenvironments in Sacramento, CA, and Milwaukee, WI, and to improve our understanding of the impact of the urban environment on human exposure to air toxics. Data were obtained from microenvironmental concentration measurements, integrated, 24-h personal measurements, indoor and outdoor pollutant monitors at the participants' residences, from ambient pollutant monitors at fixed-site locations in each city, and from real-time diaries and questionnaires completed by the technicians and participants. As part of this study, a model to predict personal exposures based on individual time/activity data was developed for comparison to measured concentrations. Predicted concentrations were generally within 25% of the measured concentrations. The microenvironments that people encounter daily provide for widely varying exposures to aldehydes. The activities that occur in those microenvironments can modulate the aldehyde concentrations dramatically, especially for environments such as "indoor at home." By considering personal activity, location (microenvironment), duration in the microenvironment, and a knowledge of the general concentrations of aldehydes in the various microenvironments, a simple model can do a reasonably good job of predicting the time-averaged personal exposures to aldehydes, even in the absence of monitoring data. Although concentrations of aldehydes measured indoors at the participants' homes tracked well with personal exposure, there were instances where personal exposures and indoor concentrations differed significantly. Key to the ability to predict exposure based on time/activity data is the quality and completeness of the microenvironmental

  9. The effects from placental exposure

    International Nuclear Information System (INIS)

    Kawamoto, Sadahisa

    1975-01-01

    Investigations of the effects on the people who had received placental exposure at either Hiroshima or Nagasaki were discussed. All of the subjects were children who had been born at either Hiroshima or Nagasaki between noon of 31, May, 1946 and the atomic-bomb detornation. Deaths of embryos and neonates were determined by the radiation dosage and the growth phase of embryos. Bifid uvula and a slight decrease of number of lumbar vertebra were observed in 14 males and 3 females at Nagasaki. Mental deficiency occurred in 25% of the children whose mothers had received radiation at Nagasaki, and in 8% at Hiroshima. The occurrence of microcephaly was high at both places in the children who had received placental exposure of more than 150 rad. A significant retardation of growth was observed in those who had had a high radiation dosage. Congenitally abnormal persistence of pupillary membrane was very frequently observed in the group which had received a high dosage of radiation. Concerning progeria, mortality of infants under one year of age was increased in the group which had received a high dosage of radiation, but mortality statistics should continue to be observed. (Kanao, N.)

  10. Personal solar UVR exposure studies using a new miniature electronic dosimeter/datalogger

    International Nuclear Information System (INIS)

    Gies, H.P.; Roy, C.R.; Toomey, S.; Borland, R.; Dixon, H.

    1996-01-01

    Full text: The Australian Radiation Laboratory (ARL) has been involved in a number of different collaborative studies around Australia using polysulphone (PS) film dosimeters in the measurement of personal exposure to solar ultraviolet radiation (UVR) (Herlihy E et al, Photochem Photobiol 60:288-294, 1994; Gies HP et al, Photochem Photobiol 62:1015-1021, 1995). These PS dosimeters have proven useful in measuring cumulative exposures during different outdoor occupational and recreational activities. Recent advances in both UV photodiodes and miniature dataloggers have allowed the development of UV dosimeters which can log the incident UVR exposure with time (Diffey BL and Saunders PJ, Photochem Photobiol 61:615-618, 1995). This provides information on the variation of UVR exposure with time of day and also on the effect of variations in local environment, activity and possibly behaviour on exposure. A pilot study to examine the performance of the UV dosimeter/ datalogger and to refine a suitable questionnaire for a much larger follow up study was undertaken in 1995. Two of the new dosimeter/dataloggers were available and a third, less portable unit was used to monitor ambient solar UVR. The site chosen was a recreation park within 5 km of ARL where calibrated ambient UVR monitoring occurs. The UVR exposures of people undertaking outdoor activities were measured. The subjects wore the UV detector attached to clothing on their back, so that it was out of sight and therefore less likely to cause them to consciously modify their behaviour during their activity. On completion the subjects were asked a number of standard questions about their activities while wearing the UV dosimeters. Of particular interest was whether the data collected could be used to determine whether subjects have modified their behaviour when in the sun as a result of educational campaigns on sun exposure run by the Cancer Councils. Comparison of the subjects UV data record with the simultaneous

  11. [Multiple mere exposure effect: category evaluation measured in the Go/No-go association task (GNAT)].

    Science.gov (United States)

    Kawakami, Naoaki; Yoshida, Fujio

    2011-12-01

    The effect on likability of multiple subliminal exposures to the same person was investigated. Past studies on the mere exposure effect indicated a correlation between the frequency of repeated exposure to the same stimulus and likability. We proposed that exposure to various stimuli of the same person would have a stronger effect on likability. Participants were subliminally exposed to photographs of a person's face taken from seven angles (multi-angle-exposure) three times each (Experiment 1), or photographs of a person with seven facial expressions (multi-expression-exposure) three times each (Experiment 2). Then, the likability toward the exposed person was measured using the Go/No-go Association Task. The results indicated that the effect of the multiple exposures from various angles was equivalent to exposure to only one full-face photograph shown 21 times (Experiment 1). Moreover, likability was significantly higher in the case of exposure to various facial expressions than for exposure to only a single facial expression (Experiment 2). The results suggest that exposure to various stimuli in a category is more effective than repeated exposure to a single stimulus for increasing likability.

  12. The mere exposure effect with scene stimuli

    OpenAIRE

    八木 , 善彦

    2016-01-01

     The mere exposure effect refers to the phenomenon where previous exposures to stimuli increasesubsequent affective preference for those stimuli. It has been indicated that with specific stimulus-category(i.e., paintings, matrices, and photographs of scene), repeated exposure has little or oppositeeffect on affective ratings. In this study, two experiments were conducted in order to explore theeffect of stimulus-category on the mere exposure effects. Photographs of young woman’s(Experiment1)a...

  13. Determinants of personal ultraviolet-radiation exposure doses on a sun holiday

    DEFF Research Database (Denmark)

    Petersen, B; Thieden, E; Philipsen, P A

    2013-01-01

    A great number of journeys to sunny destinations are sold to the Danish population every year. We suspect that this travel considerably increases personal annual ultraviolet-radiation (UVR) exposure doses. This is important because such exposure is the main cause of skin cancer, and studies have...

  14. Use of population exposure frequency distributions to simulate effects of policy interventions on NO2 exposure

    Science.gov (United States)

    Dimitroulopoulou, C.; Ashmore, M. R.; Terry, A. C.

    2017-02-01

    Health effects of air pollution on individuals depend on their personal exposure, but few modelling tools are available which can predict how the distribution of personal exposures within a city will change in response to policies to reduce emissions both indoors and outdoors. We describe a new probabilistic modelling framework (INDAIR-2/EXPAIR), which provides predictions of the personal exposure frequency distribution (PEFD) across a city to assess the effects of both reduced emissions from home sources and reduced roadside concentrations on population exposure. The model uses a national time activity database, which gives the percentage of each population group in different residential and non-residential micro-environments, and links this, for the home, to predictions of concentrations from a three-compartment model, and for non-residential microenvironments to empirical indoor/outdoor ratios. This paper presents modelled PEFDs for NO2 in the city of Leicester, for children, the elderly, and office workers, comparing results in different seasons and on different days of the week. While the mean NO2 population exposure was close to, or below the urban background concentration, the 95%ile of the PEFD was well above the urban background concentration. The relationship between both mean and 95%ile PEFD and urban background concentrations was strongly influenced by air exchange rate. The 24 h mean PEFD showed relative small differences between the population groups, with both removal of home sources and reductions of roadside concentrations on roads with a high traffic density having similar effects in reducing mean exposure. In contrast, the 1 h maximum of the PEFD was significantly higher for children and the elderly than for office workers, and showed a much greater response to reduced home emissions in these groups. The results demonstrate the importance of understanding the dynamics of NO2 exposure at a population level within different groups, if the benefits

  15. Cytogenetics observation and radiation influence evaluation of exposed persons in a discontinuous radiation exposure event

    International Nuclear Information System (INIS)

    Chen Ying; Liu Xiulin; Yang Guoshan; Ge Shili; Jin Cuizhen; Yao Bo

    2003-01-01

    The cytogenetics results and dose estimation of exposed and related persons in an discontinuous radiation exposure event were reported in this paper. According to dicentrics + ring and micronucleus results combined with clinical data, slight (middle) degree of subacute radiation symptom of the victim was diagnosed. A part of 52 examined persons were exposed to radiation in a certain degree

  16. Usage patterns of personal care products: Important factors for exposure assessment

    NARCIS (Netherlands)

    Biesterbos, J.W.H.; Dudzina, T.; Delmaar, C.J.; Bakker, M.I.; Russel, F.G.M.; Goetz, N. von; Scheepers, P.T.J.; Roeleveld, N.

    2013-01-01

    Complete information regarding the use of personal care products (PCPs) by consumers is limited, but such information is crucial for realistic consumer exposure assessment. To fill this gap, a database was created with person-oriented information regarding usage patterns and circumstances of use for

  17. Activity pattern and personal exposure to nitrogen dioxide in indoor and outdoor microenvironments.

    Science.gov (United States)

    Kornartit, C; Sokhi, R S; Burton, M A; Ravindra, Khaiwal

    2010-01-01

    People are exposed to air pollution from a range of indoor and outdoor sources. Concentrations of nitrogen dioxide (NO(2)), which is hazardous to health, can be significant in both types of environments. This paper reports on the measurement and analysis of indoor and outdoor NO(2) concentrations and their comparison with measured personal exposure in various microenvironments during winter and summer seasons. Furthermore, the relationship between NO(2) personal exposure in various microenvironments and including activities patterns were also studied. Personal, indoor microenvironments and outdoor measurements of NO(2) levels were conducted using Palmes tubes for 60 subjects. The results showed significant differences in indoor and outdoor NO(2) concentrations in winter but not for summer. In winter, indoor NO(2) concentrations were found to be strongly correlated with personal exposure levels. NO(2) concentration in houses using a gas cooker was higher in all rooms than those with an electric cooker during the winter campaign, whereas there was no significant difference noticed in summer. The average NO(2) levels in kitchens with a gas cooker were twice as high as those with an electric cooker, with no significant difference in the summer period. A time-weighted average personal exposure was calculated and compared with measured personal exposures in various indoor microenvironments (e.g. front doors, bedroom, living room and kitchen); including non-smokers, passive smokers and smoker. The estimated results were closely correlated, but showed some underestimation of the measured personal exposures to NO(2) concentrations. Interestingly, for our particular study higher NO(2) personal exposure levels were found during summer (14.0+/-1.5) than winter (9.5+/-2.4).

  18. EFFECTS OF PROACTIVE PERSONALITY ON POLITICAL SKILLS

    Directory of Open Access Journals (Sweden)

    Tahsin AKÇAKANAT

    2017-12-01

    Full Text Available The aim of this study was to determine the effect of the proactive personality on the political skills of the administrative staff working at the university. For this purpose, Proactive Personality Scale (Claes et.al., 2005 and Political Skill Inventory (Ferris et.al.:2005 were conducted for university administrative staff. The relationship between proactive personality traits and political skills of the staff was determined through correlation and regression analysis. As a result, it has been found that proactive personality has a significant effect in explaining both its general political skill and its sub-dimensions.

  19. Temporal variability of daily personal magnetic field exposure metrics in pregnant women.

    Science.gov (United States)

    Lewis, Ryan C; Evenson, Kelly R; Savitz, David A; Meeker, John D

    2015-01-01

    Recent epidemiology studies of power-frequency magnetic fields and reproductive health have characterized exposures using data collected from personal exposure monitors over a single day, possibly resulting in exposure misclassification due to temporal variability in daily personal magnetic field exposure metrics, but relevant data in adults are limited. We assessed the temporal variability of daily central tendency (time-weighted average, median) and peak (upper percentiles, maximum) personal magnetic field exposure metrics over 7 consecutive days in 100 pregnant women. When exposure was modeled as a continuous variable, central tendency metrics had substantial reliability, whereas peak metrics had fair (maximum) to moderate (upper percentiles) reliability. The predictive ability of a single-day metric to accurately classify participants into exposure categories based on a weeklong metric depended on the selected exposure threshold, with sensitivity decreasing with increasing exposure threshold. Consistent with the continuous measures analysis, sensitivity was higher for central tendency metrics than for peak metrics. If there is interest in peak metrics, more than 1 day of measurement is needed over the window of disease susceptibility to minimize measurement error, but 1 day may be sufficient for central tendency metrics.

  20. Human convection flow in spaces with and without ventilation: personal exposure to floor-released particles and cough-released droplets

    DEFF Research Database (Denmark)

    Licina, Dusan; Melikov, Arsen Krikor; Pantelic, Jovan

    2015-01-01

    The effects of the human convective boundary layer (CBL), room airflow patterns, and their velocities on personal exposure are examined. Two pollutants are studied which simulate particles released from the feet and generated at distances of 2 and 3 m by a human cough. A thermal manikin whose body...... shape, size, and surface temperatures correspond to those of an average person is used to simulate the CBL. The findings of the study reveal that for accurate predictions of personal exposure, the CBL needs to be considered, as it can transport the pollution around the human body. The best way...... to control and reduce personal exposure when the pollution originates at the feet is to employ transverse flow from in front and from the side, relative to the exposed occupant. The flow from the above opposing the CBL create the most unfavorable velocity field that can increase personal exposure by 85...

  1. Solar UV exposure among outdoor workers in Denmark measured with personal UV-B dosimeters

    DEFF Research Database (Denmark)

    Grandahl, Kasper; Mortensen, Ole Steen; Sherman, David Zim

    2017-01-01

    radiation exposure are needed to help resolve this problem. This can be done using personal ultraviolet radiation dosimeters. Methods: We consider technical and practical feasibility of measuring individual solar ultraviolet exposure at work and leisure in professions with different á priori temporal high......-level outdoor worktime, using aluminium gallium nitride (AlGaN) photodiode detector based personal UV-B dosimeters. Essential technical specifications including the spectral and angular responsivity of the dosimeters are described and pre-campaign dosimeter calibration applicability is verified. The scale...... with our specialist knowledge as occupational physicians. Conclusions: Large-scale use of personal UV-B dosimeters for measurement of solar ultraviolet radiation exposure at work and leisure in Denmark is indeed feasible from a technical and practical viewpoint. Samples of exposure data shown support...

  2. Source of Personal Exposure to PM2.5 among College Students in Beijing, China

    Science.gov (United States)

    Xie, Qiaorong; Zhu, Xianlei; Li, Xiang; Hui, Fan; Fu, Xianqiang; Zhang, Qiangbin

    2015-04-01

    The health risk from exposure to airborne particles arouses increasing public concern in Beijing, a megacity in China, where concentration of PM2.5 frequently exceeds the guideline values of World Health Organization (WHO). To investigate daily exposure to PM2.5, a personal exposure study was conducted for college students. The purpose of this study was to measure the daily PM2.5 personal exposures of students, to quantify the contributions of various microenvironments to personal exposure since students spend more than 85% of their time indoors, and to apportion the contributions of PM2.5 indoors origin and outdoor origin. In this work, a total of 320 paired indoor and outdoor PM2.5 samples were collected at eight types of microenvironments in both China University of Petroleum (suburban area) and Tsinghua University (urban area). The microenvironments were selected based on the time-activity diary finished by 1500 students from both universities. Simultaneously, the air exchange rate was measured in each microenvironment. PM2.5, elements, inorganic ions and polycyclic aromatic hydrocarbons in the samples were determined. The peak concentrations were observed in dinning halls, whereas PM2.5 in dormitories was the largest contributor to personal exposure because students spend more than half of a day there. Furthermore, source apportionment by positive matrix factorization (PMF) will be carried out to understand the source of personal exposure to PM2.5. Especially, efforts will be put on determing the contributions of primary combustion, secondary sulfate and organics, secondary nitrate, and mechanically generated PM, which present different infiltration behavior and are indoor PM2.5 of ambient origin, with help of air exchange rate data. The results would be benefit for refining the understanding of the contribution of PM2.5 of ambient (outdoor) origin to the daily PM2.5 personal exposures. Acknowledgments:This study has been funded by Beijing Municipal Commission

  3. Exposure Control Indoors with Wearable Personal Exhaust Unit

    DEFF Research Database (Denmark)

    Bolashikov, Zhecho Dimitrov; Barova, Maria I.; Melikov, Arsen Krikor

    2013-01-01

    A wearable personalized ventilation (PV) unit to reduce the risk from airborne disease contamination is reported. The PV unit consists of a nozzle, installed on a headset, which is used to locally exhaust the exhaled air before it mixes with the surroundings. Experiments at 22 °C were performed...... background air distribution at 3, 6 and 12 ACH. The use of the device showed a great potential in reducing the concentration of exhaled air in the room to the level measured under mixing ventilation alone at 12 ACH. The high potential to capture exhaled air, makes the wearable PV applicable as an efficient...

  4. Stochastic modeling of near-field exposure to parabens in personal care products

    DEFF Research Database (Denmark)

    Csiszar, Susan A.; Ernstoff, Alexi; Fantke, Peter

    2017-01-01

    Exposure assessment is a key step in determining risks to chemicals in consumer goods, including personal care products (PCPs). Exposure models can be used to estimate exposures to chemicals in the absence of biomonitoring data and as tools in chemical risk prioritization and screening. We apply...... a PCP exposure model based on the product intake fraction (PiF), which is defined as the fraction of chemical in a product that is taken in by the exposed population, to estimate chemical intake based on physicochemical properties and PCP usage characteristics. The PiF can be used to estimate route...... and pathway-specific exposures during both the use and disposal stages of a product. As a case study, we stochastically quantified population level exposures to parabens in PCPs, and compared estimates with biomarker values. We estimated exposure based on the usage of PCPs in the female US population, taking...

  5. Soft, stretchable, epidermal sensor with integrated electronics and photochemistry for measuring personal UV exposures.

    Directory of Open Access Journals (Sweden)

    Yunzhou Shi

    Full Text Available Excessive ultraviolet (UV radiation induces acute and chronic effects on the skin, eye and immune system. Personalized monitoring of UV radiation is thus paramount to measure the extent of personal sun exposure, which could vary with environment, lifestyle, and sunscreen use. Here, we demonstrate an ultralow modulus, stretchable, skin-mounted UV patch that measures personal UV doses. The patch contains functional layers of ultrathin stretchable electronics and a photosensitive patterned dye that reacts to UV radiation. Color changes in the photosensitive dyes correspond to UV radiation intensity and are analyzed with a smartphone camera. A software application has feature recognition, lighting condition correction, and quantification algorithms that detect and quantify changes in color. These color changes are then correlated with corresponding shifts in UV dose, and compared to existing UV dose risk levels. The soft mechanics of the UV patch allow for multi-day wear in the presence of sunscreen and water. Two evaluation studies serve to demonstrate the utility of the UV patch during daily activities with and without sunscreen application.

  6. Soft, stretchable, epidermal sensor with integrated electronics and photochemistry for measuring personal UV exposures.

    Science.gov (United States)

    Shi, Yunzhou; Manco, Megan; Moyal, Dominique; Huppert, Gil; Araki, Hitoshi; Banks, Anthony; Joshi, Hemant; McKenzie, Richard; Seewald, Alex; Griffin, Guy; Sen-Gupta, Ellora; Wright, Donald; Bastien, Philippe; Valceschini, Florent; Seité, Sophie; Wright, John A; Ghaffari, Roozbeh; Rogers, John; Balooch, Guive; Pielak, Rafal M

    2018-01-01

    Excessive ultraviolet (UV) radiation induces acute and chronic effects on the skin, eye and immune system. Personalized monitoring of UV radiation is thus paramount to measure the extent of personal sun exposure, which could vary with environment, lifestyle, and sunscreen use. Here, we demonstrate an ultralow modulus, stretchable, skin-mounted UV patch that measures personal UV doses. The patch contains functional layers of ultrathin stretchable electronics and a photosensitive patterned dye that reacts to UV radiation. Color changes in the photosensitive dyes correspond to UV radiation intensity and are analyzed with a smartphone camera. A software application has feature recognition, lighting condition correction, and quantification algorithms that detect and quantify changes in color. These color changes are then correlated with corresponding shifts in UV dose, and compared to existing UV dose risk levels. The soft mechanics of the UV patch allow for multi-day wear in the presence of sunscreen and water. Two evaluation studies serve to demonstrate the utility of the UV patch during daily activities with and without sunscreen application.

  7. Soft, stretchable, epidermal sensor with integrated electronics and photochemistry for measuring personal UV exposures

    Science.gov (United States)

    Shi, Yunzhou; Manco, Megan; Moyal, Dominique; Huppert, Gil; Araki, Hitoshi; Banks, Anthony; Joshi, Hemant; McKenzie, Richard; Seewald, Alex; Griffin, Guy; Sen-Gupta, Ellora; Wright, Donald; Bastien, Philippe; Valceschini, Florent; Seité, Sophie; Wright, John A.; Ghaffari, Roozbeh; Rogers, John; Balooch, Guive

    2018-01-01

    Excessive ultraviolet (UV) radiation induces acute and chronic effects on the skin, eye and immune system. Personalized monitoring of UV radiation is thus paramount to measure the extent of personal sun exposure, which could vary with environment, lifestyle, and sunscreen use. Here, we demonstrate an ultralow modulus, stretchable, skin-mounted UV patch that measures personal UV doses. The patch contains functional layers of ultrathin stretchable electronics and a photosensitive patterned dye that reacts to UV radiation. Color changes in the photosensitive dyes correspond to UV radiation intensity and are analyzed with a smartphone camera. A software application has feature recognition, lighting condition correction, and quantification algorithms that detect and quantify changes in color. These color changes are then correlated with corresponding shifts in UV dose, and compared to existing UV dose risk levels. The soft mechanics of the UV patch allow for multi-day wear in the presence of sunscreen and water. Two evaluation studies serve to demonstrate the utility of the UV patch during daily activities with and without sunscreen application. PMID:29293664

  8. Effects of occupational lead exposure.

    Science.gov (United States)

    Wang, Y L; Lu, P K; Chen, Z Q; Liang, Y X; Lu, Q M; Pan, Z Q; Shao, M

    1985-01-01

    Fifty-three workers in a battery factory, 52 solderers in a television factory, and 50 embroidery workers (a reference group) were studied. The average air lead levels of the three workplaces were 0.578 mg/m3, 0.002 mg/m3, and 0.001 mg/m3, respectively. Adverse effects in terms of clinical manifestations and biochemical criteria were evident among the battery factory workers. A significant dose-response relationship existed between the toxic effects and the air lead levels. The solderers showed no apparent abnormalities in comparison with the embroidery workers. The early clinical manifestations were dysfunction of the central nervous system, indigestion, arthralgia, and myalgia in the extremities. A positive association was observed between the prevalence of fatigue, mild abdominal pain, and arthralgia and the blood lead (PbB), urinary lead (PbU), and zinc protoporphyrin (ZPP) levels. The symptomatic threshold values of PbB, PbU, and ZPP were 30 micrograms/dl (1.5 mumol/l), 0.045 mg/l (0.2 mumol/l), and 40 micrograms/dl (0.7 mumol/l), respectively. The PbB, PbU, free erythrocyte protoporphyrin, and ZPP levels and the blood aminolevulinic dehydratase ratio could be used as indicators of lead exposure, although ZPP is preferred for a preventive monitoring program. The motor and sensory conduction velocities of the median nerve were slower in the exposed groups than in the reference group. No effects on behavioral function were observed among the solderers.

  9. Student's music exposure: Full-day personal dose measurements.

    Science.gov (United States)

    Washnik, Nilesh Jeevandas; Phillips, Susan L; Teglas, Sandra

    2016-01-01

    Previous studies have shown that collegiate level music students are exposed to potentially hazardous sound levels. Compared to professional musicians, collegiate level music students typically do not perform as frequently, but they are exposed to intense sounds during practice and rehearsal sessions. The purpose of the study was to determine the full-day exposure dose including individual practice and ensemble rehearsals for collegiate student musicians. Sixty-seven college students of classical music were recruited representing 17 primary instruments. Of these students, 57 completed 2 days of noise dose measurements using Cirrus doseBadge programed according to the National Institute for Occupational Safety and Health criterion. Sound exposure was measured for 2 days from morning to evening, ranging from 7 to 9 h. Twenty-eight out of 57 (49%) student musicians exceeded a 100% daily noise dose on at least 1 day of the two measurement days. Eleven student musicians (19%) exceeded 100% daily noise dose on both days. Fourteen students exceeded 100% dose during large ensemble rehearsals and eight students exceeded 100% dose during individual practice sessions. Approximately, half of the student musicians exceeded 100% noise dose on a typical college schedule. This finding indicates that a large proportion of collegiate student musicians are at risk of developing noise-induced hearing loss due to hazardous sound levels. Considering the current finding, there is a need to conduct hearing conservation programs in all music schools, and to educate student musicians about the use and importance of hearing protection devices for their hearing.

  10. Coaching for improved personal and organizational effectiveness

    International Nuclear Information System (INIS)

    Miller, K.; Williams, R.A.

    2002-01-01

    Leadership ability and highly developed interpersonal skills are essential for both organizational and personal effectiveness. High-performance organizations have typically taken an integrated approach to address these critical needs. One element of a comprehensive strategy to improve these key competencies is to provide both individual and work-group coaching. This paper describes what leaders at the Pt. Lepreau NGS have experienced while receiving personal and small group coaching, and the effect it has had on their overall performance effectiveness. (author)

  11. Coaching for improved personal and organizational effectiveness

    Energy Technology Data Exchange (ETDEWEB)

    Miller, K. [Point Lepreau Nuclear Generating Station, Lepreau, New Brunswick (Canada); Williams, R.A. [Briant-Williams, (Canada)

    2002-07-01

    Leadership ability and highly developed interpersonal skills are essential for both organizational and personal effectiveness. High-performance organizations have typically taken an integrated approach to address these critical needs. One element of a comprehensive strategy to improve these key competencies is to provide both individual and work-group coaching. This paper describes what leaders at the Pt. Lepreau NGS have experienced while receiving personal and small group coaching, and the effect it has had on their overall performance effectiveness. (author)

  12. Sound exposure by personal stereo, field study of young people in Denmark

    DEFF Research Database (Denmark)

    Ordoñez, Rodrigo Pizarro; Reuter, Karen; Hammershøi, Dorte

    2006-01-01

    A number of large scale studies suggest that the exposure level used with personal stereo systems should raise concern. It has been demonstrated that 1) high levels can be produced, 2) high levels are used, especially in situations with high background noise, 3) exposure levels are comparables...... with that of industrial noise exposure. In the present study, measurements of the everyday exposure levels will be measured according to principles of ISO 11904-2:2004 for students at various school levels. The measurements will be accompanied with questionnaire detailing the individual habits of use, and with assessment...... of hearing levels and OAE....

  13. A cost-effective technique for integrating personal radiation dose assessment with personal gravimetric sampling

    International Nuclear Information System (INIS)

    Strydom, R.; Rolle, R.; Van der Linde, A.

    1992-01-01

    During recent years there has been an increasing awareness internationally of radiation levels in the mining and milling of radioactive ores, including those from non-uranium mines. A major aspect of radiation control is concerned with the measurement of radiation levels and the assessment of radiation doses incurred by individual workers. Current techniques available internationally for personnel monitoring of radiation exposures are expensive and there is a particular need to reduce the cost of personal radiation monitoring in South African gold mines because of the large labour force employed. In this regard the obvious benefits of integrating personal radiation monitoring with existing personal monitoring systems already in place in South African gold mines should be exploited. A system which can be utilized for this purpose is personal gravimetric sampling. A new cost-effective technique for personal radiation monitoring, which can be fully integrated with the personal gravimetric sampling strategy being implemented on mines, has been developed in South Africa. The basic principles of this technique and its potential in South African mines are described. 9 refs., 7 figs

  14. Risk assessments for exposure of deployed military personnel to insecticides and personal protective measures used for disease-vector management.

    Science.gov (United States)

    Macedo, Paula A; Peterson, Robert K D; Davis, Ryan S

    2007-10-01

    Infectious diseases are problematic for deployed military forces throughout the world, and, historically, more military service days have been lost to insect-vectored diseases than to combat. Because of the limitations in efficacy and availability of both vaccines and therapeutic drugs, vector management often is the best tool that military personnel have against most vector-borne pathogens. However, the use of insecticides may raise concerns about the safety of their effects on the health of the military personnel exposed to them. Therefore, our objective was to use risk assessment methodologies to evaluate health risks to deployed U.S. military personnel from vector management tactics. Our conservative tier-1, quantitative risk assessment focused on acute, subchronic, and chronic exposures and cancer risks to military personnel after insecticide application and use of personal protective measures in different scenarios. Exposures were estimated for every scenario, chemical, and pathway. Acute, subchronic, and chronic risks were assessed using a margin of exposure (MOE) approach. Our MOE was the ratio of a no-observed-adverse-effect level (NOAEL) to an estimated exposure. MOEs were greater than the levels of concern (LOCs) for all surface residual and indoor space spraying exposures, except acute dermal exposure to lambda-cyhalothrin. MOEs were greater than the LOCs for all chemicals in the truck-mounted ultra-low-volume (ULV) exposure scenario. The aggregate cancer risk for permethrin exceeded 1 x 10(-6), but more realistic exposure refinements would reduce the cancer risk below that value. Overall, results indicate that health risks from exposures to insecticides and personal protective measures used by military personnel are low.

  15. Nanoparticle exposure biomonitoring: exposure/effect indicator development approaches

    Science.gov (United States)

    Marie-Desvergne, C.; Dubosson, M.; Lacombe, M.; Brun, V.; Mossuz, V.

    2015-05-01

    The use of engineered nanoparticles (NP) is more and more widespread in various industrial sectors. The inhalation route of exposure is a matter of concern (adverse effects of air pollution by ultrafine particles and asbestos). No NP biomonitoring recommendations or standards are available so far. The LBM laboratory is currently studying several approaches to develop bioindicators for occupational health applications. As regards exposure indicators, new tools are being implemented to assess potentially inhaled NP in non-invasive respiratory sampling (nasal sampling and exhaled breath condensates (EBC)). Diverse NP analytical characterization methods are used (ICP-MS, dynamic light scattering and electron microscopy coupled to energy-dispersive X-ray analysis). As regards effect indicators, a methodology has been developed to assess a range of 29 cytokines in EBCs (potential respiratory inflammation due to NP exposure). Secondly, collaboration between the LBM laboratory and the EDyp team has allowed the EBC proteome to be characterized by means of an LC-MS/MS process. These projects are expected to facilitate the development of individual NP exposure biomonitoring tools and the analysis of early potential impacts on health. Innovative techniques such as field-flow fractionation combined with ICP-MS and single particle-ICPMS are currently being explored. These tools are directly intended to assist occupational physicians in the identification of exposure situations.

  16. Nanoparticle exposure biomonitoring: exposure/effect indicator development approaches

    International Nuclear Information System (INIS)

    Marie-Desvergne, C; Dubosson, M; Mossuz, V; Lacombe, M; Brun, V

    2015-01-01

    The use of engineered nanoparticles (NP) is more and more widespread in various industrial sectors. The inhalation route of exposure is a matter of concern (adverse effects of air pollution by ultrafine particles and asbestos). No NP biomonitoring recommendations or standards are available so far. The LBM laboratory is currently studying several approaches to develop bioindicators for occupational health applications. As regards exposure indicators, new tools are being implemented to assess potentially inhaled NP in non-invasive respiratory sampling (nasal sampling and exhaled breath condensates (EBC)). Diverse NP analytical characterization methods are used (ICP-MS, dynamic light scattering and electron microscopy coupled to energy-dispersive X-ray analysis). As regards effect indicators, a methodology has been developed to assess a range of 29 cytokines in EBCs (potential respiratory inflammation due to NP exposure). Secondly, collaboration between the LBM laboratory and the EDyp team has allowed the EBC proteome to be characterized by means of an LC-MS/MS process. These projects are expected to facilitate the development of individual NP exposure biomonitoring tools and the analysis of early potential impacts on health. Innovative techniques such as field-flow fractionation combined with ICP-MS and single particle-ICPMS are currently being explored. These tools are directly intended to assist occupational physicians in the identification of exposure situations. (paper)

  17. The design of a miniature personal exposure monitor for continuous real-time data acquisition in electromagnetic field exposure assessment

    International Nuclear Information System (INIS)

    Hansen, N.H.; Conroy, T.J.; Wilson, B.W.

    1994-06-01

    The design of a small, light-weight personal exposure monitor suitable for use in EMF exposure assessment studies is nearing completion at Pacific Northwest Laboratory. The monitor is designed to be non-obtrusive, battery operated, and able to continuously record extremely low-frequency (ELF) (1Ohz--500hz) magnetic-field data. It also captures high-frequency (500hz--1OMhz) transients that exceed a preset threshold, retaining the largest transients in memory. The monitor can record one or more days of data on a single easily replaceable, credit-card-size memory (PCMCIA). A battery charge will last a minimum of one day. Batteries are rechargeable and easily replaced. A data-compression algorithm is under development that will be tailored to the efficient compression of low-frequency EMF signals and will permit data to be logged for at least one day before swapping memory cards. The memory cards are readable by a base- station computer that can perform analysis of the data. The monitor is designed to accommodate four inputs supporting full-field sensors as well as a proposed ocular exposure measurement system. Our design effort has shown that a practical personal exposure monitor for EMF can be built based on current technology, continuous logging of real-time ELF waveforms is both feasible and practical, and such a device is appropriate for proposed EMF exposure studies

  18. Personal exposure to benzene from fuel emissions among commercial fishers: comparison of two-stroke, four-stroke and diesel engines.

    Science.gov (United States)

    Kirrane, Ellen; Loomis, Dana; Egeghy, Peter; Nylander-French, Leena

    2007-03-01

    Commercial fishers are exposed to unburned hydrocarbon vapors and combustion products present in the emissions from their boat engines. The objective of this study was to measure personal exposure to benzene as a marker of fuel exposure, and to predict exposure levels across categories of carbureted two-stroke, four-stroke and diesel engines. A self-monitoring approach, employing passive monitors, was used to obtain measurements of personal exposure to benzene over time. Mixed-effect linear regression models were used to predict exposure levels, identify significant effects and determine restricted maximum likelihood estimates for within- and between-person variance components. Significant fixed effects for engine type and refueling a car or truck were identified. After controlling for refueling, predicted benzene exposure levels to fishers on boats equipped with two-stroke, four-stroke and diesel engines were 58.4, 38.9 and 15.7 microg/m3, respectively. The logged within-person variance component was 1.43, larger than the between-person variance component of 1.13, indicating that the total variation may be attributable to monitor placement, environmental conditions and other factors that change over time as well as differences between individual work practices. The health consequences of exposure to marine engine emissions are not known. The predicted levels are well below those at which health effects have been attributed, however.

  19. Medical exposure and the effects of radiation

    International Nuclear Information System (INIS)

    Okuyama, Chio

    2011-01-01

    Radiation gives cracks to genes. The influence is divided into deterministic effect with a threshold value, and the stochastic effect (tumor and genetic effect) which increases according to the exposure amount. Although we are put to various non-artificial radiations, which we cannot be avoided, on the earth, the contamination by artificial radiation can be defended. Artificial radioactive exposure includes medical exposure and non-medical exposure for example by nuclear power plant. As to medical examinations using radiation, the inquiry about the radiation exposure is increasing after the occurrence of the first nuclear power plant disaster of Fukushima. While concern about non-medical radioactive exposure increases, the uneasiness to medical irradiation is also increasing. The dose limit by artificial radioactive exposure other than medical exposure is set up in order to prevent the influence on the health. While the dose limit of the public exposure is set to the lower value than the total dose of non-artificial exposure concerning of a safety margin for all people, the dose limit of medical exposure is not defined, since it is thought that medical irradiation has a benefit for those who receive irradiation. Making an effort to decrease the radiation dose in performing the best medical treatment is the responsibility with which we are burdened. (author)

  20. Personal exposure distribution of solar erythemal ultraviolet radiation in tree shade over summer

    International Nuclear Information System (INIS)

    Parisi, A.V.; Wong, J.C.F.

    2000-01-01

    The personal radiant exposure distribution of solar erythemal UV in tree shade for an upright posture was measured, with measurements over the whole summer for a total of 17 trees. For each tree, the personal radiant exposure distribution was measured for both the morning and afternoon periods. The exposure ratios averaged over all the trees and over the morning and afternoon periods ranged from 0.16 to 0.49 for the different anatomical sites. A numerical model was employed to estimate the UV radiant exposure to humans in tree shade over the entire summer. The body sites with the higher exposure ratios in the tree shade were the vertex of the head, shoulders and forearms with radiant exposures over the summer of 1300 MED to the vertex of the head and 1100 MED to the shoulders and forearms. These radiant exposures in the shade are substantially higher than the ambient erythemal UV measured in full sun on a horizontal plane over a full summer at a more temperate northern hemisphere latitude. The average radiant exposures per day to each anatomical site for a complete day in the tree shade ranged from 4.6 to 14.6 MED. This research has provided new data that is essential to quantify human UV exposure during outdoor activities. (author)

  1. The mere exposure effect for visual image.

    Science.gov (United States)

    Inoue, Kazuya; Yagi, Yoshihiko; Sato, Nobuya

    2018-02-01

    Mere exposure effect refers to a phenomenon in which repeated stimuli are evaluated more positively than novel stimuli. We investigated whether this effect occurs for internally generated visual representations (i.e., visual images). In an exposure phase, a 5 × 5 dot array was presented, and a pair of dots corresponding to the neighboring vertices of an invisible polygon was sequentially flashed (in red), creating an invisible polygon. In Experiments 1, 2, and 4, participants visualized and memorized the shapes of invisible polygons based on different sequences of flashed dots, whereas in Experiment 3, participants only memorized positions of these dots. In a subsequent rating phase, participants visualized the shape of the invisible polygon from allocations of numerical characters on its vertices, and then rated their preference for invisible polygons (Experiments 1, 2, and 3). In contrast, in Experiment 4, participants rated the preference for visible polygons. Results showed that the mere exposure effect appeared only when participants visualized the shape of invisible polygons in both the exposure and rating phases (Experiments 1 and 2), suggesting that the mere exposure effect occurred for internalized visual images. This implies that the sensory inputs from repeated stimuli play a minor role in the mere exposure effect. Absence of the mere exposure effect in Experiment 4 suggests that the consistency of processing between exposure and rating phases plays an important role in the mere exposure effect.

  2. Temporal and spatial variability of personal exposure to radio frequency electromagnetic fields.

    Science.gov (United States)

    Frei, Patrizia; Mohler, Evelyn; Neubauer, Georg; Theis, Gaston; Bürgi, Alfred; Fröhlich, Jürg; Braun-Fahrländer, Charlotte; Bolte, John; Egger, Matthias; Röösli, Martin

    2009-08-01

    Little is known about the population's exposure to radio frequency electromagnetic fields (RF-EMF) in industrialized countries. To examine levels of exposure and the importance of different RF-EMF sources and settings in a sample of volunteers living in a Swiss city. RF-EMF exposure of 166 volunteers from Basel, Switzerland, was measured with personal exposure meters (exposimeters). Participants carried an exposimeter for 1 week (two separate weeks in 32 participants) and completed an activity diary. Mean values were calculated using the robust regression on order statistics (ROS) method. Mean weekly exposure to all RF-EMF sources was 0.13 mW/m(2) (0.22 V/m) (range of individual means 0.014-0.881 mW/m(2)). Exposure was mainly due to mobile phone base stations (32.0%), mobile phone handsets (29.1%) and digital enhanced cordless telecommunications (DECT) phones (22.7%). Persons owning a DECT phone (total mean 0.15 mW/m(2)) or mobile phone (0.14 mW/m(2)) were exposed more than those not owning a DECT or mobile phone (0.10 mW/m(2)). Mean values were highest in trains (1.16 mW/m(2)), airports (0.74 mW/m(2)) and tramways or buses (0.36 mW/m(2)), and higher during daytime (0.16 mW/m(2)) than nighttime (0.08 mW/m(2)). The Spearman correlation coefficient between mean exposure in the first and second week was 0.61. Exposure to RF-EMF varied considerably between persons and locations but was fairly consistent within persons. Mobile phone handsets, mobile phone base stations and cordless phones were important sources of exposure in urban Switzerland.

  3. Changes in the Metabolome in Response to Low-Dose Exposure to Environmental Chemicals Used in Personal Care Products during Different Windows of Susceptibility

    NARCIS (Netherlands)

    Houten, Sander M.; Chen, Jia; Belpoggi, Fiorella; Manservisi, Fabiana; Sánchez-Guijo, Alberto; Wudy, Stefan A.; Teitelbaum, Susan L.

    2016-01-01

    The consequences of ubiquitous exposure to environmental chemicals remain poorly defined. Non-targeted metabolomic profiling is an emerging method to identify biomarkers of the physiological response to such exposures. We investigated the effect of three commonly used ingredients in personal care

  4. Exposure assessment and modeling of particulate matter for asthmatic children using personal nephelometers

    Science.gov (United States)

    Wu, Chang-Fu; Delfino, Ralph J.; Floro, Joshua N.; Quintana, Penelope J. E.; Samimi, Behzad S.; Kleinman, Michael T.; Allen, Ryan W.; Sally Liu, L.-J.

    It has been shown that acute exposures to particulate matter (PM) may exacerbate asthma in children. However, most epidemiological studies have relied on time-integrated PM measurements taken at a centrally located stationary monitoring sites. In this article, we characterized children's short-term personal exposures to PM 2.5 (PM with aerodynamic diameters size-selective inlet was used to estimate real-time PM 2.5 concentrations on 20 asthmatic children, inside and outside of their residences, and at a central site. The personal and indoor pDRs were operated passively, while the home outdoor and central site instruments were operated actively. The subjects received 29.2% of their exposures at school, even though they only spent 16.4% of their time there. More precise personal clouds were estimated for the home-indoor and home-outdoor microenvironments where PM concentrations were measured. The personal cloud increased with increasing activity levels and was higher during outdoor activities than during indoor activities. We built models to predict personal PM exposures based on either microenvironmental or central-site PM 2.5 measurements, and evaluated the modeled exposures against the actual personal measurements. A multiple regression model with central site PM concentration as the main predictor had a better prediction power ( R2=0.41) than a three-microenvironmental model ( R2=0.11). We further constructed a source-specific exposure model utilizing the time-space-activity information and the particle infiltration efficiencies (mean=0.72±0.15) calculated from a recursive mass balance model. It was estimated that the mean hourly personal exposures resulting from ambient, indoor-generated, and personal activity PM 2.5 were 11.1, 5.5, and 10.0 μg/m 3, respectively, when the modeling error was minimized. The high PM 2.5 exposure to personal activities reported in our study is likely due to children's more active lifestyle as compared with older adult subjects in

  5. Assessment of personal exposure to airborne nanomaterials: Evaluation of a novel sampler

    International Nuclear Information System (INIS)

    Faure, Bertrand; Dozol, Hélène; Brouard, Christophe; Guiot, Arnaud; Clavaguera, Simon

    2017-01-01

    A novel sampler, the NANOBADGE, has been developed to assess personal exposure to nano-objects, agglomerates and aggregates (NOAA) at the workplace. The NANOBADGE collects particles on filters subsequently analyzed by X-Ray Fluorescence spectroscopy (XRF), which provides a mass-based quantification with chemical selectivity. The NANOBADGE was benchmarked against a scanning mobility particle sizer (SMPS) and a DiSCmini by carrying out simultaneous measurements on test aerosols of ZnO or TiO 2 for particle sizes between 20 and 400 nm for which the DiSCmini has its highest accuracy. The effective density and shape of the NOAA present in the test aerosols were determined experimentally to compare number-based data obtained with the SMPS and the DiSCmini with mass-based data obtained with the NANOBADGE. The agreement between the SMPS and the NANOBADGE sampler was within ± 25 % on all test aerosols. The converted DiSCmini data matched the SMPS and sampler data for polydisperse aerosols in the specified size range as long as the DiSCmini assumptions meet the aerosol characteristics (i.e. lognormal size distribution with a given geometric standard deviation σg = 1.9). The detection limits of the NANOBADGE sampler were in the order of tens of nanograms per filter, which is low enough to reliably detect exposure levels below the recommended exposure limit (REL) of the National Institute for Occupational Safety and Health (NIOSH) and the Institut National de Recherche et de Sécurité (INRS) for ultrafine ZnO and TiO 2 even for short-term exposure situations. (paper)

  6. Improving disclosure and consent: "is it safe?": new ethics for reporting personal exposures to environmental chemicals.

    Science.gov (United States)

    Brody, Julia Green; Morello-Frosch, Rachel; Brown, Phil; Rudel, Ruthann A; Altman, Rebecca Gasior; Frye, Margaret; Osimo, Cheryl A; Pérez, Carla; Seryak, Liesel M

    2007-09-01

    The recent flood of research concerning pollutants in personal environmental and biological samples-blood, urine, breastmilk, household dust and air, umbilical cord blood, and other media-raises questions about whether and how to report results to individual study participants. Clinical medicine provides an expert-driven framework, whereas community-based participatory research emphasizes participants' right to know and the potential to inform action even when health effects are uncertain. Activist efforts offer other models. We consider ethical issues involved in the decision to report individual results in exposure studies and what information should be included. Our discussion is informed by our experience with 120 women in a study of 89 pollutants in homes and by interviews with other researchers and institutional review board staff.

  7. Exposures to atmospheric effects in the entertainment industry.

    Science.gov (United States)

    Teschke, Kay; Chow, Yat; van Netten, Chris; Varughese, Sunil; Kennedy, Susan M; Brauer, Michael

    2005-05-01

    Theatrical fogs are commonly used in the entertainment industry to create special atmospheric effects during filming and live productions. We examined exposures to mineral oil-and glycol-based theatrical fogs to determine what fluids and effects were commonly used, to measure the size distributions of the aerosols, and to identify factors associated with personal exposure levels. In nonperformance jobs in a range of production types (television, film, live theater, and concerts),we measured airborne concentrations of inhalable aerosol,aldehydes, and polycyclic aromatic hydrocarbons, and collected observations about the sites and tasks performed. Both mineral oil and glycols were observed in use on about one-half the production days in the study. The most common effect produced was a generalized haze over the entire set. Mean personal inhalable aerosol concentrations were 0.70 mg/m3(range 0.02 to 4.1). The mean proportion of total aerosol mass less than 3.5 microns in aerodynamic diameter was 61%. Exposures were higher when mineral oils, rather than glycols, were used to generate fogs. Higher exposures were also associated with movie and television productions, with using more than one fog machine, with increased time spent in visible fog, and for those employed as "grips." Decreased exposures were associated with increasing room temperature, with increasing distance from fog machines, and for those employed as "sound technicians." Exposures to theatrical fogs are just beginning to be measured. It is important to consider these exposures in light of any health effects observed, since existing occupational exposure limits were developed in other industries where the aerosol composition differs from that of theatrical fogs.

  8. Development of a TL personal dosimeter identifiable PA exposure, and comparison with commercial TL dosimeters

    International Nuclear Information System (INIS)

    Kwon, J.W.; Kim, H.K.; Lee, J.K.; Kim, J.L.

    2004-01-01

    A single-dosimeter worn on the anterior surface of the body of a worker was found to significantly underestimate the effective dose to the worker when the radiation comes from the back. Several researchers suggested that this sort of underestimation can be corrected to a certain extent by using an extra dosimeter on the back. However, use of multiple dosimeters also has disadvantages such as complication in control or incurrence of extra cost. Instead of the common multi-dosimeter approach, in this study, a single dosimeter introducing asymmetric filters which enabled to identify PA exposure was designed, and its dose evaluation algorithm for AP-PA mixed radiation fields was established. A prototype TL personal dosimeter was designed and constructed. The Monte Carlo simulations were utilized in the design process and verified by experiments. The dosimeter and algorithm were applicable to photon radiation having an effective energy beyond 100 keV in AP-PA mixed radiation fields. A simplified performance test based on ANSI N13.11 showed satisfactory results. Considering that the requirements of the International Electrotechnical Commission (IEC) and the American National Standards Institute (ANSI) with regard to the dosimeter on angular dependency is reinforced, the dosimeter and the dose evaluation algorithm developed in this study provides a useful approach in practical personal dosimetry against inhomogeneous high energy radiation fields. (author)

  9. Personal PM2.5 exposure and markers of oxidative stress in blood

    DEFF Research Database (Denmark)

    Sørensen, Mettte; Daneshvar, Bahram; Hansen, Max

    2003-01-01

    wAmbient particulate air pollution assessed as outdoor concentrations of particulate matter less than or equal to 2.5 mum in diameter (PM2.5) in urban background has been associated with cardiovascular diseases at the population level. However, the significance of individual exposure...... and the involved mechanisms remain uncertain. We measured personal PM2.5 and carbon black exposure in 50 students four times in 1 year and analyzed blood samples for markers of protein and lipid oxidation, for red blood cell (RBC) and platelet counts, and for concentrations of hemoglobin and fibrinogen. We...... analyzed protein oxidation in terms of gamma-glutamyl semialdehyde in hemoglobin (HBGGS) and 2-aminoadipic semialdehyde in hemoglobin (HBAAS) and plasma proteins (PLAAS), and lipid peroxidation was measured as malondialdehyde (MDA) in plasma. Median exposures were 16.1 mug/m(3) for personal PM2.5 exposure...

  10. Occupational exposure to ultrafine particles among airport employees--combining personal monitoring and global positioning system

    DEFF Research Database (Denmark)

    Møller, Karina Lauenborg; Thygesen, Lau Caspar; Schipperijn, Jasper

    2014-01-01

    BACKGROUND: Exposure to ultrafine particles (UFP) has been linked to cardiovascular and lung diseases. Combustion of jet fuel and diesel powered handling equipment emit UFP resulting in potentially high exposure levels among employees working at airports. High levels of UFP have been reported...... at several airports, especially on the apron, but knowledge on individual exposure profiles among different occupational groups working at an airport is lacking. PURPOSE: The aim of this study was to compare personal exposure to UFP among five different occupational groups working at Copenhagen Airport (CPH......). METHOD: 30 employees from five different occupational groups (baggage handlers, catering drivers, cleaning staff and airside and landside security) at CPH were instructed to wear a personal monitor of particle number concentration in real time and a GPS device. The measurements were carried out on 8 days...

  11. An analysis of factors that influence personal exposure to toluene and xylene in residents of Athens, Greece

    Directory of Open Access Journals (Sweden)

    Linos Athena

    2006-02-01

    Full Text Available Abstract Background Personal exposure to pollutants is influenced by various outdoor and indoor sources. The aim of this study was to evaluate the exposure of Athens citizens to toluene and xylene, excluding exposure from active smoking. Methods Passive air samplers were used to monitor volunteers, their homes and various urban sites for one year, resulting in 2400 measurements of toluene and xylene levels. Since both indoor and outdoor pollution contribute significantly to human exposure, volunteers were chosen from occupational groups who spend a lot of time in the streets (traffic policemen, bus drivers and postmen, and from groups who spend more time indoors (teachers and students. Data on individual and house characteristics were obtained using a questionnaire completed at the beginning of the study; a time-location-activity diary was also completed daily by the volunteers in each of the six monitoring campaigns. Results Average personal toluene exposure varied over the six monitoring campaigns from 53 to 80 μg/m3. Urban and indoor concentrations ranged from 47 – 84 μg/m3 and 30 – 51 μg/m3, respectively. Average personal xylene exposure varied between 56 and 85 μg/m3 while urban and indoor concentrations ranged from 53 – 88 μg/m3 and 27 – 48 μg/m3, respectively. Urban pollution, indoor residential concentrations and personal exposures exhibited the same pattern of variation during the measurement periods. This variation among monitoring campaigns might largely be explained by differences in climate parameters, namely wind speed, humidity and amount of sunlight. Conclusion In Athens, Greece, the time spent outdoors in the city center during work or leisure makes a major contribution to exposure to toluene and xylene among non-smoking citizens. Indoor pollution and means of transportation contribute significantly to individual exposure levels. Other indoor residential characteristics such as recent painting and mode of heating

  12. Quantifying human exposure to air pollution--moving from static monitoring to spatio-temporally resolved personal exposure assessment.

    Science.gov (United States)

    Steinle, Susanne; Reis, Stefan; Sabel, Clive Eric

    2013-01-15

    Quantifying human exposure to air pollutants is a challenging task. Ambient concentrations of air pollutants at potentially harmful levels are ubiquitous in urban areas and subject to high spatial and temporal variability. At the same time, every individual has unique activity-patterns. Exposure results from multifaceted relationships and interactions between environmental and human systems, adding complexity to the assessment process. Traditionally, approaches to quantify human exposure have relied on pollutant concentrations from fixed air quality network sites and static population distributions. New developments in sensor technology now enable us to monitor personal exposure to air pollutants directly while people are moving through their activity spaces and varying concentration fields. The literature review on which this paper is based on reflects recent developments in the assessment of human exposure to air pollution. This includes the discussion of methodologies and concepts, and the elaboration of approaches and study designs applied in the field. We identify shortcomings of current approaches and discuss future research needs. We close by proposing a novel conceptual model for the integrated assessment of human exposure to air pollutants taking into account latest technological capabilities and contextual information. Copyright © 2012 Elsevier B.V. All rights reserved.

  13. Use of an aggregate exposure model to estimate consumer exposure to fragrance ingredients in personal care and cosmetic products.

    Science.gov (United States)

    Safford, B; Api, A M; Barratt, C; Comiskey, D; Daly, E J; Ellis, G; McNamara, C; O'Mahony, C; Robison, S; Smith, B; Thomas, R; Tozer, S

    2015-08-01

    Ensuring the toxicological safety of fragrance ingredients used in personal care and cosmetic products is essential in product development and design, as well as in the regulatory compliance of the products. This requires an accurate estimation of consumer exposure which, in turn, requires an understanding of consumer habits and use of products. Where ingredients are used in multiple product types, it is important to take account of aggregate exposure in consumers using these products. This publication investigates the use of a newly developed probabilistic model, the Creme RIFM model, to estimate aggregate exposure to fragrance ingredients using the example of 2-phenylethanol (PEA). The output shown demonstrates the utility of the model in determining systemic and dermal exposure to fragrances from individual products, and aggregate exposure. The model provides valuable information not only for risk assessment, but also for risk management. It should be noted that data on the concentrations of PEA in products used in this article were obtained from limited sources and not the standard, industry wide surveys typically employed by the fragrance industry and are thus presented here to illustrate the output and utility of the newly developed model. They should not be considered an accurate representation of actual exposure to PEA. Copyright © 2015 Elsevier Inc. All rights reserved.

  14. Neurophysiological effects of lead exposure

    Energy Technology Data Exchange (ETDEWEB)

    Rosen, I.; Wildt, K.; Gullberg, B.; Berlin, M.

    1983-10-01

    A series of neurophysiological variables was measured for men occupationally exposed to lead. The results were related to the degree of lead exposure and to the concentrations of lead and zinc protoporphyrin in blood. A small but significant correlation was observed between lead exposure and motor and sensory conduction velocities in the lower limbs, the conduction velocities of slow motor fibers in the upper limbs, and also sensory nerve action potentials. It is suggested that a neurophysiological examination should be considered in the surveillance of the health of lead workers.

  15. Assessment of radiation exposure of nuclear medicine staff using personal TLD dosimeters and charcoal detectors

    Energy Technology Data Exchange (ETDEWEB)

    Jimenez, F.; Garcia-Talavera, M.; Pardo, R.; Deban, L. [Valladolid Univ., Dept. de Quimica Analitica, Facultad de Ciencias (Spain); Garcia-Talavera, P.; Singi, G.M.; Martin, E. [Hospital Clinico Univ., Servicio de Medicina Nuclear, Salamanca (Spain)

    2006-07-01

    Although the main concern regarding exposure to ionizing radiation for nuclear medicine workers is external radiation, inhalation of radionuclides can significantly contribute to the imparted doses. We propose a new approach to assess exposure to inhalation of {sup 131}I based on passive monitoring using activated charcoal detectors. We compared the inhalation doses to the staff of a nuclear medicine department, based on the measurements derived from charcoal detectors placed at various locations, and the external doses monitored using personal TLD dosimeters. (authors)

  16. Assessment of radiation exposure of nuclear medicine staff using personal TLD dosimeters and charcoal detectors

    International Nuclear Information System (INIS)

    Jimenez, F.; Garcia-Talavera, M.; Pardo, R.; Deban, L.; Garcia-Talavera, P.; Singi, G.M.; Martin, E.

    2006-01-01

    Although the main concern regarding exposure to ionizing radiation for nuclear medicine workers is external radiation, inhalation of radionuclides can significantly contribute to the imparted doses. We propose a new approach to assess exposure to inhalation of 131 I based on passive monitoring using activated charcoal detectors. We compared the inhalation doses to the staff of a nuclear medicine department, based on the measurements derived from charcoal detectors placed at various locations, and the external doses monitored using personal TLD dosimeters. (authors)

  17. Development of a personal multi-pollutant exposure sampler for particulate matter and criteria gases

    Energy Technology Data Exchange (ETDEWEB)

    Chang, I.T.; Sarnat, J.; Wolfson, J.M.; Rojas-Bracho, L.; Suh, H.H.; Koutrakis, P. [Harvard Univ., Boston, MA (United States). School of Public Health

    1999-12-01

    A novel personal sampler is reported which allows simultaneous measurement of PM{sub 2,5}, and PM{sub 10}, ozone, nitrogen dioxide, and sulfur dioxide. This method combines previously used samplers for personal mass measurement with passive samplers for criteria gases and uses a single pump. Preliminarily results are reported for laboratory chamber tests and field comparisons with reference methods for both mass and criteria gases. These results demonstrate the suitability of this sampler of exposure assessment studies. (authors)

  18. Personal exposure to carcinogenic polycyclic aromatic hydrocarbons in the Czech Republic

    Czech Academy of Sciences Publication Activity Database

    Švecová, Vlasta; Topinka, Jan; Solanský, I.; Rössner ml., Pavel; Šrám, Radim

    2013-01-01

    Roč. 23, č. 4 (2013), s. 350-355 ISSN 1559-0631 R&D Projects: GA MŽP(CZ) SP/1B3/8/08; GA MŠk 2B08005 Institutional support: RVO:68378041 Keywords : personal monitoring * personal exposure * air pollution Subject RIV: DN - Health Impact of the Environment Quality Impact factor: 3.050, year: 2013

  19. Mobile phones as monitors of personal exposure to air pollution: Is this the future?

    Science.gov (United States)

    Nyarku, Mawutorli; Mazaheri, Mandana; Jayaratne, Rohan; Dunbabin, Matthew; Rahman, Md Mahmudur; Uhde, Erik

    2018-01-01

    Mobile phones have a large spectrum of applications, aiding in risk prevention and improving health and wellbeing of their owners. So far, however, they have not been used for direct assessment of personal exposure to air pollution. In this study, we comprehensively evaluated the first, and the only available, mobile phone—BROAD Life—equipped with air pollution sensors (PM2.5 and VOC), to answer the question whether this technology is a viable option in the quest of reducing the burden of disease to air pollution. We tested its performance, applicability and suitability for the purpose by subjecting it to varied concentrations of different types of aerosol particles (cigarette smoke, petrol exhaust and concrete dust) and formaldehyde under controlled laboratory conditions, as well as to ambient particles during field measurements. Six reference instruments were used in the study: AEROTRAK Optical Particle Counter (OPC model number 9306), DustTrak, Aerodynamic Particle Counter (APS), Scanning Mobility Particle Sizer (SMPS), Tapered Element Oscillating Microbalance (TEOM) and Formaldehyde Analyser. Overall, we found that the phone’s response was linear at higher particle number concentrations in the chamber, above 5 and 10 μg m-3, for combustion and concrete dust particles, respectively, and for higher formaldehyde concentrations, making it potentially suitable for applications in polluted environments. At lower ambient concentrations of particles around 10 ug m-3 and 20 μg m-3 for PM2.5 and PM10, respectively, the phone’s response was below its noise level, suggesting that it is not suitable for ambient monitoring under relatively clean urban conditions. This mobile phone has a number of limitations that may hinder its use in personal exposure and for continuous monitoring. Despite these limitations, it may be used for comparative assessments, for example when comparing outcomes of intervention measures or local impacts of air pollution sources. It should

  20. Mobile phones as monitors of personal exposure to air pollution: Is this the future?

    Directory of Open Access Journals (Sweden)

    Mawutorli Nyarku

    Full Text Available Mobile phones have a large spectrum of applications, aiding in risk prevention and improving health and wellbeing of their owners. So far, however, they have not been used for direct assessment of personal exposure to air pollution. In this study, we comprehensively evaluated the first, and the only available, mobile phone-BROAD Life-equipped with air pollution sensors (PM2.5 and VOC, to answer the question whether this technology is a viable option in the quest of reducing the burden of disease to air pollution. We tested its performance, applicability and suitability for the purpose by subjecting it to varied concentrations of different types of aerosol particles (cigarette smoke, petrol exhaust and concrete dust and formaldehyde under controlled laboratory conditions, as well as to ambient particles during field measurements. Six reference instruments were used in the study: AEROTRAK Optical Particle Counter (OPC model number 9306, DustTrak, Aerodynamic Particle Counter (APS, Scanning Mobility Particle Sizer (SMPS, Tapered Element Oscillating Microbalance (TEOM and Formaldehyde Analyser. Overall, we found that the phone's response was linear at higher particle number concentrations in the chamber, above 5 and 10 μg m-3, for combustion and concrete dust particles, respectively, and for higher formaldehyde concentrations, making it potentially suitable for applications in polluted environments. At lower ambient concentrations of particles around 10 ug m-3 and 20 μg m-3 for PM2.5 and PM10, respectively, the phone's response was below its noise level, suggesting that it is not suitable for ambient monitoring under relatively clean urban conditions. This mobile phone has a number of limitations that may hinder its use in personal exposure and for continuous monitoring. Despite these limitations, it may be used for comparative assessments, for example when comparing outcomes of intervention measures or local impacts of air pollution sources. It

  1. Mobile phones as monitors of personal exposure to air pollution: Is this the future?

    Science.gov (United States)

    Nyarku, Mawutorli; Mazaheri, Mandana; Jayaratne, Rohan; Dunbabin, Matthew; Rahman, Md Mahmudur; Uhde, Erik; Morawska, Lidia

    2018-01-01

    Mobile phones have a large spectrum of applications, aiding in risk prevention and improving health and wellbeing of their owners. So far, however, they have not been used for direct assessment of personal exposure to air pollution. In this study, we comprehensively evaluated the first, and the only available, mobile phone-BROAD Life-equipped with air pollution sensors (PM2.5 and VOC), to answer the question whether this technology is a viable option in the quest of reducing the burden of disease to air pollution. We tested its performance, applicability and suitability for the purpose by subjecting it to varied concentrations of different types of aerosol particles (cigarette smoke, petrol exhaust and concrete dust) and formaldehyde under controlled laboratory conditions, as well as to ambient particles during field measurements. Six reference instruments were used in the study: AEROTRAK Optical Particle Counter (OPC model number 9306), DustTrak, Aerodynamic Particle Counter (APS), Scanning Mobility Particle Sizer (SMPS), Tapered Element Oscillating Microbalance (TEOM) and Formaldehyde Analyser. Overall, we found that the phone's response was linear at higher particle number concentrations in the chamber, above 5 and 10 μg m-3, for combustion and concrete dust particles, respectively, and for higher formaldehyde concentrations, making it potentially suitable for applications in polluted environments. At lower ambient concentrations of particles around 10 ug m-3 and 20 μg m-3 for PM2.5 and PM10, respectively, the phone's response was below its noise level, suggesting that it is not suitable for ambient monitoring under relatively clean urban conditions. This mobile phone has a number of limitations that may hinder its use in personal exposure and for continuous monitoring. Despite these limitations, it may be used for comparative assessments, for example when comparing outcomes of intervention measures or local impacts of air pollution sources. It should be kept

  2. Neurobehavioral and neurodevelopmental effects of pesticide exposures

    DEFF Research Database (Denmark)

    London, Leslie; Beseler, Cheryl; Bouchard, Maryse F

    2012-01-01

    The association between pesticide exposure and neurobehavioral and neurodevelopmental effects is an area of increasing concern. This symposium brought together participants to explore the neurotoxic effects of pesticides across the lifespan. Endpoints examined included neurobehavioral, affective ...

  3. Modeling personal exposure to traffic related air pollutants

    NARCIS (Netherlands)

    Montagne, D.R.

    2015-01-01

    The first part of this thesis is about the VE3SPA project. Land use regression (LUR) models are often used to predict the outdoor air pollution at the home address of study participants, to study long-term effects of air pollution. While several studies have documented that PM2.5 mass measured at a

  4. Personality, depressive symptoms and prior trauma exposure of new recruits at two Metropolitan Police Service academies in South Africa

    OpenAIRE

    U Subramaney; E Libhaber; N Pitts; M Vorster

    2012-01-01

    Background. Police officers are predisposed to trauma exposure. The development of depression and post-traumatic stress disorder (PTSD) may be influenced by personality style, prior exposure to traumatic events and prior depression. Objectives. To describe the personality profiles of new Metropolitan Police Service (MPS) officers, and to determine the association between personality profiles, trauma exposure and depressive symptoms. Methods. We performed a cross-sectional analysis o...

  5. Experimental study on human exposure to occupant generated pollutants in rooms with ductless personalized ventilation

    DEFF Research Database (Denmark)

    Melikov, Arsen Krikor; Bolashikov, Zhecho Dimitrov; Lu, Pengfei

    2014-01-01

    The performance of “ductless” personalized ventilation in conjunction with displacement ventilation with regard to exposure to different body bioeffluents was studied. Experiments were performed in a full-scale room furnished as a double office. Room air temperature was kept at 26 oC. Two breathing...... modes for the ductless personalized and displacement ventilation were tested. The location of the bioeffluent source affected the spread of body bioeffluents in the space. The ductless personalized ventilation provided cleaner air to both occupants than displacement ventilation alone. Occupants using...... the ”ductless” system will perceive the supplied air quality as superior compared to displacement ventilation alone....

  6. Between-country comparison of whole-body SAR from personal exposure data in Urban areas.

    Science.gov (United States)

    Joseph, Wout; Frei, Patrizia; Röösli, Martin; Vermeeren, Günter; Bolte, John; Thuróczy, György; Gajšek, Peter; Trček, Tomaž; Mohler, Evelyn; Juhász, Péter; Finta, Viktoria; Martens, Luc

    2012-12-01

    In five countries (Belgium, Switzerland, Slovenia, Hungary, and the Netherlands), personal radio frequency electromagnetic field measurements were performed in different microenvironments such as homes, public transports, or outdoors using the same exposure meters. From the mean personal field exposure levels (excluding mobile phone exposure), whole-body absorption values in a 1-year-old child and adult male model were calculated using a statistical multipath exposure method and compared for the five countries. All mean absorptions (maximal total absorption of 3.4 µW/kg for the child and 1.8 µW/kg for the adult) were well below the International Commission on Non-Ionizing Radiation Protection (ICNIRP) basic restriction of 0.08 W/kg for the general public. Generally, incident field exposure levels were well correlated with whole-body absorptions (SAR(wb) ), although the type of microenvironment, frequency of the signals, and dimensions of the considered phantom modify the relationship between these exposure measures. Exposure to the television and Digital Audio Broadcasting band caused relatively higher SAR(wb) values (up to 65%) for the 1-year-old child than signals at higher frequencies due to the body size-dependent absorption rates. Frequency Modulation (FM) caused relatively higher absorptions (up to 80%) in the adult male. Copyright © 2012 Wiley Periodicals, Inc.

  7. Influence of internet exposure on sexual behaviour of young persons in an urban district of Southwest Nigeria.

    Science.gov (United States)

    Arulogun, Oyedunni Sola; Ogbu, Ifeyinwa Arinze; Dipeolu, Isaac Oluwafemi

    2016-01-01

    The proportion of young people exposed to pornographic materials through the internet in Nigeria is increasing. However, the influence of the exposure on their sexual behaviour has not been fully explored. This study therefore explored the effects of internet exposure on the sexual behaviour of young persons in Ibadan North Local Government Area of southwest Nigeria. A survey of 413 young persons was done using a pretested self-administered questionnaire which included questions on internet exposure and its influence on behaviour. Data were analysed using descriptive statistics, Chi-square test and logistic regression. Mean age of males was 21.7 ± 3.4 years while that of females was 20.9 ± 3.2 years. Forty-nine percent of the respondents used the internet for the first time between the ages of 15-19 years. Main source of information about the internet was friends (63.3%) and 99.3% accessed the internet from cybercafé. Seventy-two percent had ever stumbled on pornographic sites. Reactions included glancing through before closing (45.2%), closure of the sites (38.5%), and minimizing page to view later (12.5%). Post-exposure influence on behaviour included engagement in oral sex (48.3%), body tattoo (18.3%), having multiple sexual partners (11.6%) and homosexuality (5.0%). More males (95% CI OR =1.245-6.465) and frequent users (95% CI OR =1.168-3.497) were likely to report a change in sexual behaviour. Internet use was common among the young persons. Interventions aimed at reducing exposure to sexual content on internet targeting young persons especially the males and cybercafé operators are advocated.

  8. The association of LUR modeled PM2.5 elemental composition with personal exposure

    International Nuclear Information System (INIS)

    Montagne, Denise; Hoek, Gerard; Nieuwenhuijsen, Mark; Lanki, Timo; Pennanen, Arto; Portella, Meritxell; Meliefste, Kees; Wang, Meng; Eeftens, Marloes; Yli-Tuomi, Tarja; Cirach, Marta; Brunekreef, Bert

    2014-01-01

    Background and aims: Land use regression (LUR) models predict spatial variation of ambient concentrations, but little is known about the validity in predicting personal exposures. In this study, the association of LUR modeled concentrations of PM 2.5 components with measured personal concentrations was determined. The elements of interest were copper (Cu), iron (Fe), potassium (K), nickel (Ni), sulfur (S), silicon (Si), vanadium (V) and zinc (Zn). Methods: In Helsinki (Finland), Utrecht (the Netherlands) and Barcelona (Spain) five participants from urban background, five from suburban background and five from busy street sites were selected in each city (15 participants per city). Outdoor, indoor and personal 96-hour PM 2.5 samples were collected by the participants over periods of two weeks in three different seasons (winter, summer and spring/autumn) and the overall average was calculated. Elemental composition was measured by ED-XRF spectrometry. The LUR models for the average ambient concentrations of each element were developed by the ESCAPE project. Results: LUR models predicted the within-city variation of average outdoor Cu and Fe concentrations moderately well (range in R 2 27–67% for Cu and 24–54% for Fe). The outdoor concentrations of the other elements were not well predicted. The LUR modeled concentration only significantly correlated with measured personal Fe exposure in Utrecht and Ni and V in Helsinki. The LUR model predictions did not correlate with measured personal Cu exposure. After excluding observations with an indoor/outdoor ratio of > 1.5, modeled Cu outdoor concentrations correlated with indoor concentrations in Helsinki and Utrecht and personal concentrations in Utrecht. The LUR model predictions were associated with measured outdoor, indoor and personal concentrations for all elements when the data for the three cities was pooled. Conclusions: Within-city modeled variation of elemental composition of PM 2.5 did not predict measured

  9. Effects of radiation exposure from radiopharmaceuticals used in diagnostic studies

    International Nuclear Information System (INIS)

    Witcofski, R.L.

    1981-01-01

    In the United States about 90 percent of man-made radiation exposure to the general population is from the use of radiation in diagnostic medicine. Although the doses of radiation from these procedures to individuals are generally quite small, large numbers of people are exposed. Estimates of the radiation doses associated with such use in the healing arts are approximately 15 million person-rem to the general population from diagnostic x ray and 3.3 million person-rem from the diagnostic use of radiopharmaceuticals. The purpose of this paper is to present what is known about the possible effects of radiation from diagnostic radiopharmaceuticals

  10. Cadmium and children: Exposure and health effects.

    NARCIS (Netherlands)

    Schoeters, G.; Hond, E. Den; Zuurbier, M.; Naginiene, R.; Hazel, P.J. van den; Stilianakis, N.; Ronchetti, R.; Koppe, J.G.

    2006-01-01

    Cadmium exposure and accumulation in the body start at young age. Exposure routes in children are mainly via food, environmental tobacco smoke and house dust. Excretion from the body is limited. Cadmium accumulation in the kidney is responsible for effects such as nephrotoxicity and osteoporosis

  11. Inter-comparison of personal monitors for nanoparticles exposure at workplaces and in the environment

    NARCIS (Netherlands)

    Todea, A.M.; Beckmann, S.; Kaminski, H.; Bard, D.; Bau, S.; Clavaguera, S.; Dahmann, D.; Dozol, H.; Dziurowitz, N.; Elihn, K.; Fierz, M.; Lidén, G.; Meyer-Plath, A.; Monz, C.; Neumann, V.; Pelzer, J.; Simonow, B.K.; Thali, P.; Tuinman, I.; Vleuten, A. van der; Vroomen, H.; Asbach, C.

    2017-01-01

    Personal monitors based on unipolar diffusion charging (miniDiSC/DiSCmini, NanoTracer, Partector) can be used to assess the individual exposure to nanoparticles in different environments. The charge acquired by the aerosol particles is nearly proportional to the particle diameter and, by

  12. Pre-exposure prophylaxis for MSM and transgender persons in early adopting countries

    NARCIS (Netherlands)

    Hoornenborg, Elske; Krakower, Douglas S.; Prins, Maria; Mayer, Kenneth H.

    2017-01-01

    : Pre-exposure prophylaxis (PrEP) is a potent and underutilized HIV prevention tool. In this paper we review the state of knowledge regarding PrEP implementation for men who have sex with men and transgender persons in early adopting countries. We focus on implementation of PrEP in demonstration

  13. Concentrations and assessment of exposure to siloxanes and synthetic musks in personal care products from China

    International Nuclear Information System (INIS)

    Lu Yan; Yuan Tao; Wang Wenhua; Kannan, Kurunthachalam

    2011-01-01

    We investigated the concentrations and profiles of 15 siloxanes (four cyclic siloxanes, D 4 -D 7 ; 11 linear siloxanes, L 4 -L 14 ), four synthetic musks (two polycyclic musks, HHCB and AHTN; two nitro musks, MX and MK), and HHCB-lactone, in 158 personal care products marketed in China. Siloxanes were detected in 88% of the samples analyzed, at concentrations as high as 52.6 mg g -1 ; Linear siloxanes were the predominant compounds. Among synthetic musks, more than 80% of the samples contained at least one of these compounds, and their total concentrations were as high as 1.02 mg g -1 . HHCB was the predominant musk in all of the samples analyzed, on average, accounting for 52% of the total musk concentrations. Based on the median concentrations of siloxanes and musks and the average daily usage amounts of consumer products, dermal exposure rates in adults were calculated to be 3.69 and 3.38 mg d -1 for siloxanes and musks, respectively. - Highlights: → Siloxanes and synthetic musks are determined in personal care products. → Highest siloxane concentration was 52.6 mg g -1 . → Highest musk concentration was 1.02 mg g -1 . → Daily dermal exposure rates of siloxanes and musks were in mg levels. → Dermal exposure is a major pathway of human exposure to siloxanes and musks. - Dermal application of several personal care products is a major source of human exposure to cyclic and linear siloxanes.

  14. Personal exposure to PM2.5 and biomarkers of DNA damage

    DEFF Research Database (Denmark)

    Sørensen, Mette; Autrup, Herman; Hertel, Ole

    2003-01-01

    Ambient particulate air pollution assessed as outdoor concentrations of particulate matter PM(2.5)) has been associated with an increased cancer risk. However, outdoor PM(2.5) concentrations may not be the best measure of the individual particle exposure that is a sum...... of many sources besides outdoor particle levels, e.g., environmental tobacco smoke and cooking. We measured personal PM(2.5) and black smoke exposure in 50 students four times over 1 year and analyzed for biomarkers of different types of DNA damages. Ambient PM(2.5) concentrations were also measured...... collections were analyzed for 8-oxodG and 1-hydroxypyrene. Personal PM(2.5) exposure was found to be a predictor of 8-oxodG in lymphocyte DNA with an 11% increase in 8-oxodG/10 microg/m(3) increase in personal PM(2.5) exposure (P = 0.007). No other associations between exposure markers and biomarkers could...

  15. Personal PM2.5 exposure and markers of oxidative stress in blood

    DEFF Research Database (Denmark)

    Sørensen, Mette; Daneshvar, Bahram; Hansen, Max

    2003-01-01

    Ambient particulate air pollution assessed as outdoor concentrations of particulate matter less than or equal to 2.5 micro m in diameter (PM(2.5)) in urban background has been associated with cardiovascular diseases at the population level. However, the significance of individual exposure...... and the involved mechanisms remain uncertain. We measured personal PM(2.5) and carbon black exposure in 50 students four times in 1 year and analyzed blood samples for markers of protein and lipid oxidation, for red blood cell (RBC) and platelet counts, and for concentrations of hemoglobin and fibrinogen. We...... analyzed protein oxidation in terms of gamma-glutamyl semialdehyde in hemoglobin (HBGGS) and 2-aminoadipic semialdehyde in hemoglobin (HBAAS) and plasma proteins (PLAAS), and lipid peroxidation was measured as malondialdehyde (MDA) in plasma. Median exposures were 16.1 micro g/m(3) for personal PM(2.5...

  16. Personal Care Product Use in Pregnancy and the Postpartum Period: Implications for Exposure Assessment

    Directory of Open Access Journals (Sweden)

    Carly Lang

    2016-01-01

    Full Text Available Concern regarding the potential for developmental health risks associated with certain chemicals (e.g., phthalates, antibacterials used in personal care products is well documented; however, current exposure data for pregnant women are limited. The objective of this study was to describe the pattern of personal care product use in pregnancy and the post-partum period. Usage patterns of personal care products were collected at six different time points during pregnancy and once in the postpartum period for a cohort of 80 pregnant women in Ottawa, Canada. The pattern of use was then described and groups of personal care product groups commonly used together were identified using hierarchical cluster analysis. The results showed that product use varied by income and country of birth. General hygiene products were the most commonly used products and were consistently used over time while cosmetic product use declined with advancing pregnancy and post-delivery. Hand soaps and baby products were reported as used more frequently after birth. This study is the first to track personal care product use across pregnancy and into the postpartum period, and suggests that pregnant populations may be a unique group of personal care product users. This information will be useful for exposure assessments.

  17. Personal exposure to pesticide among workers engaged in pesticide container recycling operations.

    Science.gov (United States)

    Guidotti, T L; Yoshida, K; Clough, V

    1994-12-01

    Pesticide container handling operations in western Canada were examined to determine the exposure of workers to residual pesticide in sorting, metal-container crushing, metal-container shredding, plastic-container shredding, metal washing, and metal melting. Environmental exposure monitoring and biological monitoring were applied, including measurement of pesticide deposition density on outer clothing (test coveralls and other protective wear), deposition on fabric and gauze patches under the outer clothing, inhalation of airborne pesticide residues, dislodgement of pesticide residues by hand washing, and pre- and postexposure urinary excretion of pesticide (2,4-D). Exposure levels were highly variable; some variability was accounted for by work practices or lapses in protection. The highest levels of exposure were observed for metal washing, metal crushing, and metal shredding; sorting and plastic shredding were intermediate, and metal melting was associated with very little exposure. Urinary 2,4-D excretion, as an indicator of internal dose, correlated most closely with exposure by the inhalation route, and both were highest for metal washing and shredding. Deposition of pesticide on garments was highest for metal crushing. Melting of washed metal does not appear to present a significant hazard of exposure. Recommendations are proposed for the protection of workers emphasizing health and safety guidelines, worker education, personal hygiene, exposure and health monitoring, and record-keeping, and specific recommendations for each process. These recommendations apply to all pesticide container recycling operations except melting of washed metal containers.

  18. Personal Exposure to PM2.5 in the Megacity of Mexico: A Multi-Mode Transport Study

    Directory of Open Access Journals (Sweden)

    Iván Y. Hernández-Paniagua

    2018-02-01

    Full Text Available Recurrent personal exposure to ambient PM2.5 is associated with adverse human health effects, in particular on the respiratory and cardiovascular systems. Here, we present an assessment of personal exposure and inhalation of PM2.5 for five modes of transport (walking, cycling, public bus (trolleybus and diesel bus, conventional car (CC and hybrid-electric car (HEC and two routes of similar distance, along a major road in the Mexico City metropolitan area (MCMA. Arithmetic average exposure concentrations ranged from 16.5 ± 6.5 µg m−3 for walking to 81.7 ± 9.1 µg m−3 for cycling (henceforth shown as average ±1 SD, with no significant differences with geometric averages. The maximum exposure concentration of 110.9 µg m−3 was observed for the conventional car. The highest exposure concentrations depended on route and the mode of transport, being observed for cycling and walking. The PM2.5 measurements showed large spatial heterogeneity in the exposure levels for walking and cycling, while public buses and private transport showed less spatial heterogeneity. The greatest peaks in PM2.5 coincided with 4-way intersections for all modes of transport, being positively influenced by traffic density. The mass of PM2.5 inhaled depended mostly on the mode of transport, and ranged between 1.0 ± 0.3 and 30.1 ± 14.2 µg km−1 for the HEC and bicycle, respectively. Local area PM2.5 increments identified as ‘residuals’ after subtraction of data recorded at the closest fixed monitoring site from exposure concentrations along the studied road suggested that inhalation for bicycle and diesel buses is strongly influenced by vehicular emissions. Residuals estimated for the trolleybus, CC and HEC confirmed a lower inhalation than for the other modes of transport evaluated due to protection by the cabin.

  19. Health Effects of Chronic Arsenic Exposure

    Directory of Open Access Journals (Sweden)

    Young-Seoub Hong

    2014-09-01

    Full Text Available Arsenic is a unique element with distinct physical characteristics and toxicity whose importance in public health is well recognized. The toxicity of arsenic varies across its different forms. While the carcinogenicity of arsenic has been confirmed, the mechanisms behind the diseases occurring after acute or chronic exposure to arsenic are not well understood. Inorganic arsenic has been confirmed as a human carcinogen that can induce skin, lung, and bladder cancer. There are also reports of its significant association to liver, prostate, and bladder cancer. Recent studies have also suggested a relationship with diabetes, neurological effects, cardiac disorders, and reproductive organs, but further studies are required to confirm these associations. The majority of research to date has examined cancer incidence after a high exposure to high concentrations of arsenic. However, numerous studies have reported various health effects caused by chronic exposure to low concentrations of arsenic. An assessment of the health effects to arsenic exposure has never been performed in the South Korean population; thus, objective estimates of exposure levels are needed. Data should be collected on the biological exposure level for the total arsenic concentration, and individual arsenic concentration by species. In South Korea, we believe that biological exposure assessment should be the first step, followed by regular health effect assessments.

  20. Biomarkers of carcinogen exposure and early effects.

    OpenAIRE

    2006-01-01

    The purpose of this review is to summarise the current situation regarding the types and uses of biomarkers of exposure and effect for the main classes of food-derived genotoxic carcinogens, and to consider some aspects of the intercomparison between these biomarkers. The biomarkers of exposure and early effects of carcinogens that have been most extensively developed are those for genotoxic agents and for compounds that generate hydroxyl radicals and other reactive radical species, and it is...

  1. Personal exposure to PM2.5, black smoke and NO2 in Copenhagen: relationship to bedroom and outdoor concentrations covering seasonal variation.

    Science.gov (United States)

    Sørensen, Mette; Loft, Steffen; Andersen, Helle Vibeke; Raaschou-Nielsen, Ole; Skovgaard, Lene Theil; Knudsen, Lisbeth E; Nielsen, Ivan V; Hertel, Ole

    2005-09-01

    Epidemiological studies have found negative associations between human health and particulate matter in urban air. In most studies outdoor monitoring of urban background has been used to assess exposure. In a field study, personal exposure as well as bedroom, front door and background concentrations of PM(2.5), black smoke (BS), and nitrogen dioxide (NO(2)) were measured during 2-day periods in 30 subjects (20-33 years old) living and studying in central parts of Copenhagen. The measurements were repeated in the four seasons. Information on indoor exposure sources such as environmental tobacco smoke (ETS) and burning of candles was collected by questionnaires. The personal exposure, the bedroom concentration and the front door concentration was set as outcome variable in separate models and analysed by mixed effect model regression methodology, regarding subject levels as a random factor. Seasons were defined as a dichotomised grouping of outdoor temperature (above and below 8 degrees C). For NO(2) there was a significant association between personal exposure and both the bedroom, the front door and the background concentrations, whereas for PM(2.5) and BS only the bedroom and the front door concentrations, and not the background concentration, were significantly associated to the personal exposure. The bedroom concentration was the strongest predictor of all three pollution measurements. The association between the bedroom and front door concentrations was significant for all three measurements, and the association between the front door and the background concentrations was significant for PM(2.5) and NO(2), but not for BS, indicating greater spatial variation for BS than for PM(2.5) and NO(2). For NO(2), the relationship between the personal exposure and the front door concentration was dependent upon the "season", with a stronger association in the warm season compared with the cold season, and for PM(2.5) and BS the same tendency was seen. Time exposed to

  2. The Association Between Psychopathic Personality Traits and Victimization and Exposure to Violence in a Sample of Saudi Arabian Youth.

    Science.gov (United States)

    Beaver, Kevin M; Al-Ghamdi, Mohammed Said; Kobeisy, Ahmed Nezar; Alqurashi, Fathiyah H; Connolly, Eric J; Schwartz, Joseph A

    2016-06-01

    Psychopathic personality traits have been shown to increase the odds of a wide range of antisocial outcomes. Very little research, however, has examined the association between psychopathy and the risk of personal victimization. The current study address this gap in the literature by examining the association between scores on the Levenson Self-Report Psychopathy scale and a self-reported measure of victimization by using cross-sectional data drawn from a sample of youth residing in Jeddah, Saudi Arabia (N = 311). The results revealed a positive and statistically significant association between LSPR scores and the odds of being victimized. Additional analyses revealed that two mediators-arrest history and exposure to delinquent peers-were related to personal victimization, but neither of these measures mediated the effects of LSPR scores on victimization. Whether these findings would generalize to other nations remains an issue awaiting future research.

  3. Health effects of laser printer emissions: a controlled exposure study.

    Science.gov (United States)

    Karrasch, S; Simon, M; Herbig, B; Langner, J; Seeger, S; Kronseder, A; Peters, S; Dietrich-Gümperlein, G; Schierl, R; Nowak, D; Jörres, R A

    2017-07-01

    Ultrafine particles emitted from laser printers are suspected to elicit adverse health effects. We performed 75-minute exposures to emissions of laser printing devices (LPDs) in a standardized, randomized, cross-over manner in 23 healthy subjects, 14 mild, stable asthmatics, and 15 persons reporting symptoms associated with LPD emissions. Low-level exposures (LLE) ranged at the particle background (3000 cm -3 ) and high-level exposures (HLE) at 100 000 cm -3 . Examinations before and after exposures included spirometry, body plethysmography, transfer factors for CO and NO (TLCO, TLNO), bronchial and alveolar NO, cytokines in serum and nasal secretions (IL-1β, IL-5, IL-6, IL-8, GM-CSF, IFNγ, TNFα), serum ECP, and IgE. Across all participants, no statistically significant changes occurred for lung mechanics and NO. There was a decrease in volume-related TLNO that was more pronounced in HLE, but the difference to LLE was not significant. ECP and IgE increased in the same way after exposures. Nasal IL-6 showed a higher increase after LLE. There was no coherent pattern regarding the responses in the participant subgroups or single sets of variables. In conclusion, the experimental acute responses to short but very high-level LPD exposures were small and did not indicate clinically relevant effects compared to low particle number concentrations. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  4. Skin sensitisation quantitative risk assessment (QRA) based on aggregate dermal exposure to methylisothiazolinone in personal care and household cleaning products.

    Science.gov (United States)

    Ezendam, J; Bokkers, B G H; Bil, W; Delmaar, J E

    2018-02-01

    Contact allergy to preservatives is an important public health problem. Ideally, new substances should be evaluated for the risk on skin sensitisation before market entry, for example by using a quantitative risk assessment (QRA) as developed for fragrances. As a proof-of-concept, this QRA was applied to the preservative methylisothiazolinone (MI), a common cause of contact allergy. MI is used in different consumer products, including personal care products (PCPs) and household cleaning products (HCPs). Aggregate exposure to MI in PCPs and HCPs was therefore assessed with the Probabilistic Aggregated Consumer Exposure Model (PACEM). Two exposure scenarios were evaluated: scenario 1 calculated aggregate exposure on actual MI product concentrations before the restricted use in PCPs and scenario 2 calculated aggregate exposure using the restrictions for MI in PCPs. The QRA for MI showed that in scenarios 1 and 2, the proportion of the population at risk for skin sensitisation is 0.7% and 0.5%, respectively. The restricted use of MI in PCPs does not seem very effective in lowering the risk on skin sensitization. To conclude, it is important to consider aggregate exposure from the most important consumer products into consideration in the risk assessment. Copyright © 2018 Elsevier Ltd. All rights reserved.

  5. Personal exposure to mobile phone frequencies and well-being in adults: a cross-sectional study based on dosimetry.

    Science.gov (United States)

    Thomas, Silke; Kühnlein, Anja; Heinrich, Sabine; Praml, Georg; Nowak, Dennis; von Kries, Rüdiger; Radon, Katja

    2008-09-01

    The use of mobile phone telecommunication has increased in recent years. In parallel, there is growing concern about possible adverse health effects of cellular phone networks. We used personal dosimetry to investigate the association between exposure to mobile phone frequencies and well-being in adults. A random population-based sample of 329 adults living in four different Bavarian towns was assembled for the study. Using a dosimeter (ESM-140 Maschek Electronics), we obtained an exposure profile over 24 h for three mobile phone frequency ranges (measurement interval 1 s, limit of determination 0.05 V/m). Exposure levels over waking hours were totalled and expressed as mean percentage of the International Commission on Non-Ionizing Radiation Protection (ICNIRP) reference level. Each participant reported acute symptoms in a day-long diary. Data on five groups of chronic symptoms and potential confounders were assessed during an interview. The overall exposure to high-frequency electromagnetic fields was markedly below the ICNIRP reference level. We did not find any statistically significant association between the exposure and chronic symptoms or between the exposure and acute symptoms. Larger studies using mobile phone dosimetry are warranted to confirm these findings. Copyright 2008 Wiley-Liss, Inc.

  6. The FARE: A new way to express FAlls Risk among older persons including physical activity as a measure of Exposure

    NARCIS (Netherlands)

    Wijlhuizen, G.J.; Chorus, A.M.J.; Hopman-Rock, M.

    2010-01-01

    Background: Common expressions of falls risk do not include exposure to hazards. We compared two expressions: the commonly used population incidence (fallers per 1000 person-years) and the FARE (FAlls Risk by Exposure): the number of fallers per 1000 physically active person-days. Methods:

  7. The FARE: a new way to express FAlls Risk among older persons including physical activity as a measure of exposure

    NARCIS (Netherlands)

    Wijlhuizen, G.J.; Chorus, A.M.J.; Hopman-Rock, M.

    2010-01-01

    Background: Common expressions of falls risk do not include exposure to hazards. We compared two expressions: the commonly used population incidence (fallers per 1000 person-years) and the FARE (FAlls Risk by Exposure): the number of fallers per 1000 physically active person-days. Methods:

  8. Employee Motivation for Personal Development Plan Effectiveness

    Science.gov (United States)

    Eisele, Lisa; Grohnert, Therese; Beausaert, Simon; Segers, Mien

    2013-01-01

    Purpose: This article aims to understand conditions under which personal development plans (PDPs) can effectively be implemented for professional learning. Both the organization's manner of supporting the PDP practice as well as the individual employee's motivation is taken into account. Design/ methodology/approach: A questionnaire was…

  9. Reducing personal exposure to particulate air pollution improves cardiovascular health in patients with coronary heart disease.

    Science.gov (United States)

    Langrish, Jeremy P; Li, Xi; Wang, Shengfeng; Lee, Matthew M Y; Barnes, Gareth D; Miller, Mark R; Cassee, Flemming R; Boon, Nicholas A; Donaldson, Ken; Li, Jing; Li, Liming; Mills, Nicholas L; Newby, David E; Jiang, Lixin

    2012-03-01

    Air pollution exposure increases cardiovascular morbidity and mortality and is a major global public health concern. We investigated the benefits of reducing personal exposure to urban air pollution in patients with coronary heart disease. In an open randomized crossover trial, 98 patients with coronary heart disease walked on a predefined route in central Beijing, China, under different conditions: once while using a highly efficient face mask, and once while not using the mask. Symptoms, exercise, personal air pollution exposure, blood pressure, heart rate, and 12-lead electrocardiography were monitored throughout the 24-hr study period. Ambient air pollutants were dominated by fine and ultrafine particulate matter (PM) that was present at high levels [74 μg/m³ for PM(2.5) (PM with aerodynamic diamater reduced maximal ST segment depression (-142 vs. -156 μV, p = 0.046) over the 24-hr period. When the face mask was used during the prescribed walk, mean arterial pressure was lower (93 ± 10 vs. 96 ± 10 mmHg, p = 0.025) and heart rate variability increased (high-frequency power: 54 vs. 40 msec², p = 0.005; high-frequency normalized power: 23.5 vs. 20.5 msec, p = 0.001; root mean square successive differences: 16.7 vs. 14.8 msec, p = 0.007). However, mask use did not appear to influence heart rate or energy expenditure. Reducing personal exposure to air pollution using a highly efficient face mask appeared to reduce symptoms and improve a range of cardiovascular health measures in patients with coronary heart disease. Such interventions to reduce personal exposure to PM air pollution have the potential to reduce the incidence of cardiovascular events in this highly susceptible population.

  10. Novel database for exposure to fragrance ingredients in cosmetics and personal care products.

    Science.gov (United States)

    Comiskey, D; Api, A M; Barratt, C; Daly, E J; Ellis, G; McNamara, C; O'Mahony, C; Robison, S H; Safford, B; Smith, B; Tozer, S

    2015-08-01

    Exposure of fragrance ingredients in cosmetics and personal care products to the population can be determined by way of a detailed and robust survey. The frequency and combinations of products used at specific times during the day will allow the estimation of aggregate exposure for an individual consumer, and to the sample population. In the present study, habits and practices of personal care and cosmetic products have been obtained from market research data for 36,446 subjects across European countries and the United States in order to determine the exposure to fragrance ingredients. Each subject logged their product uses, time of day and body application sites in an online diary for seven consecutive days. The survey data did not contain information on the amount of product used per occasion or body measurements, such as weight and skin surface area. Nevertheless, this was found from the literature where the likely amount of product used per occasion or body measurement could be probabilistically chosen from distributions of data based on subject demographics. The daily aggregate applied consumer product exposure was estimated based on each subject's frequency of product use, and Monte Carlo simulations of their likely product amount per use and body measurements. Statistical analyses of the habits and practices and consumer product exposure are presented, which show the robustness of the data and the ability to estimate aggregate consumer product exposure. Consequently, the data and modelling methods presented show potential as a means of performing ingredient safety assessments for personal care and cosmetics products. Copyright © 2015 Elsevier Inc. All rights reserved.

  11. Human health effects of exposure to cadmium

    Energy Technology Data Exchange (ETDEWEB)

    Hallenbeck, W.H.

    1986-01-01

    The health effects of human exposure to cadmium are discussed with emphases on intake, absorption, body burden, and excretion; osteomalacia in Japan; hypertension; and proteinuria, emphysema, osteomalacia, and cancer in workers. Elevated blood pressure has not been observed as a result of excessive exposures to cadmium in Japan or the workplace. Renal tubular dysfunction and consequent proteinuria is generally accepted as the main effect following long-term, low-level exposure to cadmium. Studies of workers show that proteinuria may develop after the first year of exposure or many years after the last exposure. Proteinuria and deterioration of renal function may continue even after cessation of exposure. The immediate health significance of low-level proteinuria is still under debate. However, there is evidence that long-term renal tubular dysfunction may lead to abnormalities of calcium metabolism and osteomalacia. The few autopsy and cross-sectional studies of workers do not permit conclusions to be drawn regarding the relationship between cadmium exposure and emphysema. Retrospective and historical-prospective studies are needed to settle this important question. No conclusive evidence has been published regarding cadmium-induced cancer in humans. However, there is sufficient evidence to regard cadmium as a suspect renal and prostate carcinogen. Because of equivocal results and the absence of dose-response relationships, the studies reviewed should be used with caution in making regulatory decisions and low-dose risk assessments. 62 references.

  12. Human health effects of exposure to cadmium

    Energy Technology Data Exchange (ETDEWEB)

    Hallenbeck, W.H.

    1984-02-15

    The health effects of human exposure to cadmium are discussed with emphasis on intake, absorption, body burden, and excretion; osteomalacia in Japan; hypertension; and proteinuria, emphysema, osteomalacia, and cancer in workers. Elevated blood pressure has not been observed as a result of excessive exposures to cadmium in Japan or the workplace. Renal tubular dysfunction and consequent proteinuria is generally accepted as the main effect following long-term, low-level exposure to cadmium. Studies of workers show that proteinuria may develop after the first year of exposure or many years after the last exposure. Proteinuria and deterioration of renal function may continue even after cessation of exposure. The immediate health significance of low-level proteinuria is still under debate. However, there is evidence that long-term renal tubular dysfunction may lead to abnormalities of calcium metabolism and osteomalacia. The few autopsy and cross-sectional studies of workers do not permit conclusions to be drawn regarding the relationship between cadmium exposure and emphysema. Retrospective and historical-prospective studies are needed to settle this important question. No conclusive evidence has been published regarding cadmium-induced cancer in humans. However, there is sufficient evidence to regard cadmium as a suspect renal and prostate carcinogen. Because of equivocal results and the absence of dose-response relationships, the studies reviewed should be used with caution in making regulatory decisions and low-dose risk assessments.

  13. The Corporate Effects of Personal Taxation

    Directory of Open Access Journals (Sweden)

    Richard H. Fosberg

    2013-07-01

    Full Text Available Under fairly general conditions it is shown that changes in personal tax rates on dividend and capital gains income will change a firm’s share price, cost of equity capital and the shape of its cost of equity capital function. A personal tax rate change will also affect a firm’s optimal capital structure and its WACC. In 2003, the personal tax rates of dividend and capital gains income were lowered for many tax payers. The model presented here predicts that the effects of the 2003 tax cuts should include a rise share prices, an increase in the amount of equity capital in firm’s capital structures and a significant increase in the number of firms increasing or initiating dividend payments. Various empirical analyses cited in this study show that all of these things did occur.

  14. Assessment of exposure to composite nanomaterials and development of a personal respiratory deposition sampler for nanoparticles

    Science.gov (United States)

    Cena, Lorenzo

    2011-12-01

    The overall goals of this doctoral dissertation are to provide knowledge of workers' exposure to nanomaterials and to assist in the development of standard methods to measure personal exposure to nanomaterials in workplace environments. To achieve the first goal, a field study investigated airborne particles generated from the weighing of bulk carbon nanotubes (CNTs) and the manual sanding of epoxy test samples reinforced with CNTs. This study also evaluated the effectiveness of three local exhaust ventilation (LEV) conditions (no LEV, custom fume hood and biosafety cabinet) for control of exposure to particles generated during sanding of CNT-epoxy nanocomposites. Particle number and respirable mass concentrations were measured with direct-read instruments, and particle morphology was determined by electron microscopy. Sanding of CNT-epoxy nanocomposites released respirable size airborne particles with protruding CNTs very different in morphology from bulk CNTs that tended to remain in clusters (>1mum). Respirable mass concentrations in the operator's breathing zone were significantly greater when sanding took place in the custom hood (p <0.0001) compared to the other LEV conditions. This study found that workers' exposure was to particles containing protruding CNTs rather than to bulk CNT particles. Particular attention should be placed in the design and selection of hoods to minimize exposure. Two laboratory studies were conducted to realize the second goal. Collection efficiency of submicrometer particles was evaluated for nylon mesh screens with three pore sizes (60, 100 and 180 mum) at three flow rates (2.5, 4, and 6 Lpm). Single-fiber efficiency of nylon mesh screens was then calculated and compared to a theoretical estimation expression. The effects of particle morphology on collection efficiency were also experimentally measured. The collection efficiency of the screens was found to vary by less than 4% regardless of particle morphology. Single

  15. Fragranced consumer products: exposures and effects from emissions.

    Science.gov (United States)

    Steinemann, Anne

    2016-01-01

    Fragranced consumer products, such as cleaning supplies, air fresheners, and personal care products, are a primary source of indoor air pollutants and personal exposure. Previous research indicates that fragranced products can trigger adverse health effects, with implications for workplaces and public places. This is the first study to examine the multiple dimensions of exposures related to fragranced products and effects in the US population. The study investigated the prevalence and types of fragranced product exposures, associated health effects, awareness of product emissions, and preferences for fragrance-free policies and environments. Data were collected using an online survey with a nationally representative population ( n  = 1136) of adults in the USA. Overall, 34.7 % of the population reported health problems, such as migraine headaches and respiratory difficulties, when exposed to fragranced products. Further, 15.1 % have lost workdays or a job due to fragranced product exposure in the workplace. Also, 20.2 % would enter a business but then leave as quickly as possible if they smell air fresheners or some fragranced product. Over 50 % of the population would prefer that workplaces, health care facilities and professionals, hotels, and airplanes were fragrance-free. While prior research found that common fragranced products, even those called green and organic, emitted hazardous air pollutants, more than two thirds of the population were not aware of this, and over 60 % would not continue to use a fragranced product if they knew it emitted such pollutants. Results from this study provide strong evidence that fragranced products can trigger adverse health effects in the general population. The study also indicates that reducing exposure to fragranced products, such as through fragrance-free policies, can provide cost-effective and relatively simple ways to reduce risks and improve air quality and health.

  16. The impact of exposure to radio frequency electromagnetic fields on chronic well-being in young people--a cross-sectional study based on personal dosimetry.

    Science.gov (United States)

    Heinrich, Sabine; Thomas, Silke; Heumann, Christian; von Kries, Rüdiger; Radon, Katja

    2011-01-01

    A possible influence of radio frequency electromagnetic field (RF EMF) exposure on health outcomes was investigated in various studies. The main problem of previous studies was exposure assessment. The aim of our study was the investigation of a possible association between RF EMF and chronic well-being in young persons using personal dosimetry. 3022 children and adolescents were randomly selected from the population registries of four Bavarian cities in Germany (participation 52%). Personal interview data on chronic symptoms, socio-demographic characteristics and potential confounders were collected. A 24-h radio frequency exposure profile was generated using a personal dosimeter. Exposure levels over waking hours were expressed as mean percentage of the International Commission on Non-Ionizing Radiation Protection (ICNIRP) reference level. Half of the children and nearly every adolescent owned a mobile phone which was used only for short durations per day. Measured exposure was far below the current ICNIRP reference levels. The most reported chronic symptom in children and adolescents was fatigue. No statistically significant association between measured exposure and chronic symptoms was observed. Our results do not indicate an association between measured exposure to RF EMF and chronic well-being in children and adolescents. Prospective studies investigating potential long-term effects of RF EMF are necessary to confirm our results. Copyright © 2010 Elsevier Ltd. All rights reserved.

  17. Assessing the importance of different exposure metrics and time-activity data to predict 24-H personal PM2.5 exposures.

    Science.gov (United States)

    Chang, Li-Te; Koutrakis, Petros; Catalano, Paul J; Suh, Helen H

    Personal PM(2.5) data from two recent exposure studies, the Scripted Activity Study and the Older Adults Study, were used to develop models predicting 24-h personal PM(2.5) exposures. Both studies were conducted concurrently in the summer of 1998 and the winter of 1999 in Baltimore, MD. In the Scripted Activity Study, 1-h personal PM(2.5) exposures were measured. Data were used to identify significant factors affecting personal exposures and to develop 1-h personal exposure models for five different micro-environments. By incorporating the time-activity diary data, these models were then combined to develop a time-weighted microenvironmental personal model (model M1AD) to predict the 24-h PM(2.5) exposures measured for individuals in the Older Adults Study. Twenty-four-hour time-weighted models were also developed using 1-h ambient PM(2.5) levels and time-activity data (model A1AD) or using 24-h ambient PM(2.5) levels and time-activity data (model A24AD). The performance of these three models was compared to that using 24-h ambient concentrations alone (model A24). Results showed that factors affecting 1-h personal PM(2.5) exposures included air conditioning status and the presence of environmental tobacco smoke (ETS) for indoor micro-environments, consistent with previous studies. ETS was identified as a significant contributor to measured 24-h personal PM(2.5) exposures. Staying in an ETS-exposed microenvironment for 1 h elevated 24-h personal PM(2.5) exposures by approximately 4 microg/m 3 on average. Cooking and washing activities were identified in the winter as significant contributors to 24-h personal exposures as well, increasing 24-h personal PM(2.5) exposures by about 4 and 5 microg/m 3 per hour of activity, respectively. The ability of 3 microenvironmental personal exposure models to estimate 24-h personal PM(2.5) exposures was generally comparable to and consistently greater than that of model A24. Results indicated that using time-activity data with 1

  18. Quantitative evaluation of personal exposure to UV radiation of workers and general public

    International Nuclear Information System (INIS)

    Sisto, R.; Borra, M.; Casale, G. R.; Militello, A.; Siani, A. M.

    2009-01-01

    Due to meteorological conditions variability and to the variability of exposure patterns, which can be largely different during a working day, personal dosemeters use can be necessary to obtain a correct quantitative evaluation of the radiation dose absorbed by an exposed worker. Different classes of personal dosemeters exist and, among them, electronic dosemeters and poly-sulphone film dosemeters. An experimental campaign is presented conduced in a cultivated area of Tuscany and some aspects are discussed about an experimental campaign performed on a population of volunteers on a central Italy beach near Rome. The aim of the present work is to show some relevant issues in a dosimetric approach to the exposure evaluation of outdoor workers and, in general, of the public during recreational activities. (authors)

  19. Cardiovascular health effects following exposure of human volunteers during fire extinction exercises

    DEFF Research Database (Denmark)

    Andersen, Maria Helena Guerra; Saber, Anne Thoustrup; Pedersen, Peter Bøgh

    2017-01-01

    Background: Firefighters have increased risk of cardiovascular disease and of sudden death from coronary heart disease on duty while suppressing fires. This study investigated the effect of firefighting activities, using appropriate personal protective equipment (PPE), on biomarkers...... firefighting exercises in a constructed firehouse and flashover container. The subjects were instructed to extinguish fires of either wood or wood with electrical cords and mattresses. The exposure to particulate matter ( PM) was assessed at various locations and personal exposure was assessed by portable PM...

  20. Socio-environmental exposures and health outcomes among persons with sickle cell disease

    OpenAIRE

    Asnani, Monika R.; Knight Madden, Jennifer; Reid, Marvin; Greene, Lisa-Gaye; Lyew-Ayee, Parris

    2017-01-01

    There is much variability in the expression of sickle cell disease (SCD) and recent works suggest that environmental and social factors may also influence this variability. This paper aims to use geographic information systems technology to examine the association between socio-environmental exposures and health outcomes in all persons who have attended or currently attend the Sickle Cell Unit in Jamaica. Rural patients presented for clinical care at older ages and had less annual visits to c...

  1. Exposure to suicidal behaviors: A common suicide risk factor or a personal negative life event?

    Science.gov (United States)

    Harris, Keith M; Bettiol, Silvana

    2017-02-01

    Numerous suicide risk factors have been proposed but not adequately validated for epidemiology, treatment and prevention efforts. Exposures to suicidal behaviors (ESB), from family and friend suicide attempts and completions, were tested for validity as a suicidal risk factor and also for measurement and construct adequacy. An anonymous online survey yielded 713 participants (aged 18-71), who reported ESB, completed the Suicidal Affect-Behavior-Cognition Scale (SABCS), and comprised a broad spectrum on those variables. Tests of dimensionality and internal consistency showed the four ESB variables (attempts/completions through family/friends) were independent and did not form a common factor or an identifiable ESB latent trait. ESB variables were, however, associated with demographic and psychiatric histories. A battery of tests revealed no meaningful associations between ESB and total suicidality or suicide risk factors (social support, depression, anxiety, stress, satisfaction with life and emotional stability). In addition, in contrast to previous reports, young adults ( n = 200; aged 18-20) showed no increased suicidality due to ESB. Results showed no validity for ESB as a common risk factor for suicidality or other psychopathology, or as a latent trait. ESB showed evidence as a personal negative life event with individual effects and interpretations.

  2. Concentrations and assessment of exposure to siloxanes and synthetic musks in personal care products from China

    Energy Technology Data Exchange (ETDEWEB)

    Lu Yan [School of Environmental Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240 (China); Wadsworth Center, New York State Department of Health and Department of Environmental Health Sciences, School of Public Health, State University of New York at Albany, Empire State Plaza, PO Box 509, Albany, NY 12201-0509 (United States); Yuan Tao; Wang Wenhua [School of Environmental Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240 (China); Kannan, Kurunthachalam, E-mail: kkannan@wadsworth.org [Wadsworth Center, New York State Department of Health and Department of Environmental Health Sciences, School of Public Health, State University of New York at Albany, Empire State Plaza, PO Box 509, Albany, NY 12201-0509 (United States); International Joint Research Center for Persistent Toxic Substances, State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090 (China)

    2011-12-15

    We investigated the concentrations and profiles of 15 siloxanes (four cyclic siloxanes, D{sub 4}-D{sub 7}; 11 linear siloxanes, L{sub 4}-L{sub 14}), four synthetic musks (two polycyclic musks, HHCB and AHTN; two nitro musks, MX and MK), and HHCB-lactone, in 158 personal care products marketed in China. Siloxanes were detected in 88% of the samples analyzed, at concentrations as high as 52.6 mg g{sup -1}; Linear siloxanes were the predominant compounds. Among synthetic musks, more than 80% of the samples contained at least one of these compounds, and their total concentrations were as high as 1.02 mg g{sup -1}. HHCB was the predominant musk in all of the samples analyzed, on average, accounting for 52% of the total musk concentrations. Based on the median concentrations of siloxanes and musks and the average daily usage amounts of consumer products, dermal exposure rates in adults were calculated to be 3.69 and 3.38 mg d{sup -1} for siloxanes and musks, respectively. - Highlights: > Siloxanes and synthetic musks are determined in personal care products. > Highest siloxane concentration was 52.6 mg g{sup -1}. > Highest musk concentration was 1.02 mg g{sup -1}. > Daily dermal exposure rates of siloxanes and musks were in mg levels. > Dermal exposure is a major pathway of human exposure to siloxanes and musks. - Dermal application of several personal care products is a major source of human exposure to cyclic and linear siloxanes.

  3. Extending Participatory Sensing to Personal Exposure Using Microscopic Land Use Regression Models

    Directory of Open Access Journals (Sweden)

    Luc Dekoninck

    2017-05-01

    Full Text Available Personal exposure is sensitive to the personal features and behavior of the individual, and including interpersonal variability will improve the health and quality of life evaluations. Participatory sensing assesses the spatial and temporal variability of environmental indicators and is used to quantify this interpersonal variability. Transferring the participatory sensing information to a specific study population is a basic requirement for epidemiological studies in the near future. We propose a methodology to reduce the void between participatory sensing and health research. Instantaneous microscopic land-use regression modeling (µLUR is an innovative approach. Data science techniques extract the activity-specific and route-sensitive spatiotemporal variability from the data. A data workflow to prepare and apply µLUR models to any mobile population is presented. The µLUR technique and data workflow are illustrated with models for exposure to traffic related Black Carbon. The example µLURs are available for three micro-environments; bicycle, in-vehicle, and indoor. Instantaneous noise assessments supply instantaneous traffic information to the µLURs. The activity specific models are combined into an instantaneous personal exposure model for Black Carbon. An independent external validation reached a correlation of 0.65. The µLURs can be applied to simulated behavioral patterns of individuals in epidemiological cohorts for advanced health and policy research.

  4. Characteristics of carbonyl compounds in public vehicles of Beijing city: Concentrations, sources, and personal exposures

    Science.gov (United States)

    Pang, Xiaobing; Mu, Yujing

    The characteristics of carbonyl compounds (carbonyls) including concentrations, major sources, and personal exposure were investigated for 29 vehicles including taxi, bus and subway in Beijing. It was found that the taxis (Xiali, TA) and buses (Huanghe, BA) fueled by gasoline with longer service years had the higher indoor carbonyl levels (178±42.7 and 188±31.6 μg m -3) while subways energized by electricity without exhaust and the jingwa buses (BB) driven in the suburb had the lower levels with total concentrations of 98.5±26.3 and 92.1±20.3 μg m -3, respectively. Outdoor carbonyls of taxi cars and buses were nearly at the same level with their total concentrations varying from 80 to 110 μg m -3. The level of outdoor subways carbonyls was equal with the ambient air levels. Exhaust leakage, indoor material emissions, photochemical formation, and infiltration of outdoor air were considered to be the major sources to in-vehicle carbonyls. Personal exposures and cancer risk to formaldehyde and acetaldehyde were calculated for professional bus and taxi drivers, respectively. Taxi drivers had the highest cancer risk with personal exposure to formaldehyde and acetaldehyde of 212 and 243 μg day -1, respectively. The public concern should pay considerable attention to professional drivers' health.

  5. Effects of prenatal exposure to ionizing radiation

    International Nuclear Information System (INIS)

    Miller, R.W.

    1990-01-01

    Prenatal exposure to ionizing radiation induces some effects that are seen at birth and others that cannot be detected until later in life. Data from A-bomb survivors in Hiroshima and Nagasaki show a diminished number of births after exposure under 4 wk of gestational age. Although a wide array of congenital malformations has been found in animal experimentation after such exposure to x rays, in humans only small head size (exposure at 4-17 wk) and mental retardation (exposure primarily at 8-15 wk) have been observed. In Hiroshima, small head size occurred after doses of 0.10-0.19 Gy or more, and an excess of mental retardation at 0.2-0.4 Gy or more. Intelligence test scores were reduced among A-bomb survivors exposed at 8-15 wk of gestational age by 21-29 IQ points per Gy. Other effects of in-utero exposure to atomic radiation include long-lasting complex chromosome abnormalities

  6. Effects of prenatal exposure to ionizing radiation

    Energy Technology Data Exchange (ETDEWEB)

    Miller, R.W. (National Cancer Institute, Bethesda, MD (USA))

    1990-07-01

    Prenatal exposure to ionizing radiation induces some effects that are seen at birth and others that cannot be detected until later in life. Data from A-bomb survivors in Hiroshima and Nagasaki show a diminished number of births after exposure under 4 wk of gestational age. Although a wide array of congenital malformations has been found in animal experimentation after such exposure to x rays, in humans only small head size (exposure at 4-17 wk) and mental retardation (exposure primarily at 8-15 wk) have been observed. In Hiroshima, small head size occurred after doses of 0.10-0.19 Gy or more, and an excess of mental retardation at 0.2-0.4 Gy or more. Intelligence test scores were reduced among A-bomb survivors exposed at 8-15 wk of gestational age by 21-29 IQ points per Gy. Other effects of in-utero exposure to atomic radiation include long-lasting complex chromosome abnormalities.

  7. 1976 Hanford Americium exposure incident: hematologic effects

    International Nuclear Information System (INIS)

    Ragan, H.A.; Mahaffey, J.A.; Breitenstein, B.D.

    1982-05-01

    Hematologic evaluation of an individual with an initial systemic body burden of approx. 200 μCi 241 Am revealed a significant (P < 0.01) reduction of total leukocytes, neutrophils, and lymphocytes. This effect on total leukocytes and neutrophils was evident approx. 30 days after exposure, appeared to stabilize at about 3 months after exposure, and remained at this lower level thorugh a 52-months observation period. The effect on lymphocytes was apparent by 3 days after exposure, stabilizing at approx. 50% of pre-exposure values for about 7 months, with a return to pre-exposure levels in the following 4 y. There was a progressive and significant (P < 0.001) decline in platelet counts during the 52-months postexposure period. The pattern of response in erythrocyte parameters was complex. Immediately after the accident, these values were less than the pre-exposure mean level; they gradually increased (P < 0.001) for approx. 2 y and then began a progressive decline (P < 0.001)

  8. Repeated cue exposure effects on subjective and physiological indices of chocolate craving

    NARCIS (Netherlands)

    van Gucht, D.; Vansteenwegen, D.; Beckers, T.; Hermans, D.; Baeyens, F.; Van den Bergh, O.

    2008-01-01

    The aim of this study is to investigate the effects of repeated unreinforced exposure to chocolate cues in persons reporting chocolate craving. Participants in the experimental group (n ¼ 40) received 10 consecutive brief exposures to chocolate cues in each of two sessions, separated by 1-3 days.

  9. Children’s Personal Exposure Measurements to Extremely Low Frequency Magnetic Fields in Italy

    Directory of Open Access Journals (Sweden)

    Ilaria Liorni

    2016-05-01

    Full Text Available Extremely low frequency magnetic fields (ELF-MFs exposure is still a topic of concern due to their possible impact on children’s health. Although epidemiological studies claimed an evidence of a possible association between ELF-MF above 0.4 μT and childhood leukemia, biological mechanisms able to support a causal relationship between ELF-MF and this disease were not found yet. To provide further knowledge about children’s ELF-MF exposure correlated to children’s daily activities, a measurement study was conducted in Milan (Italy. Eighty-six children were recruited, 52 of whom were specifically chosen with respect to the distance to power lines and built-in transformers to oversample potentially highly exposed children. Personal and bedroom measurements were performed for each child in two different seasons. The major outcomes of this study are: (1 median values over 24-h personal and bedroom measurements were <3 μT established by the Italian law as the quality target; (2 geometric mean values over 24-h bedroom measurements were mostly <0.4 μT; (3 seasonal variations did not significantly influence personal and bedroom measurements; (4 the highest average MF levels were mostly found at home during the day and outdoors; (5 no significant differences were found in the median and geometric mean values between personal and bedroom measurements, but were found in the arithmetic mean.

  10. Socio-environmental exposures and health outcomes among persons with sickle cell disease.

    Directory of Open Access Journals (Sweden)

    Monika R Asnani

    Full Text Available There is much variability in the expression of sickle cell disease (SCD and recent works suggest that environmental and social factors may also influence this variability. This paper aims to use geographic information systems technology to examine the association between socio-environmental exposures and health outcomes in all persons who have attended or currently attend the Sickle Cell Unit in Jamaica. Rural patients presented for clinical care at older ages and had less annual visits to clinic. Persons travelled relatively long distances to seek SCD care and those travelling longer had less health maintenance visits. Urban patients had a higher prevalence of significant pain crises (69.4% vs. 55.8%, p value<0.001 and respiratory events (21.2% vs. 14%, p value<0.001. Prevalence of leg ulcers did not vary between rural and urban patients but was higher in males than in females. Females also had lower odds of having respiratory events but there was no sex difference in history of painful crises. Persons with more severe genotypes lived in higher poverty and travelled longer for healthcare services. Persons in areas with higher annual rainfall, higher mean temperatures and living farther from factories had less painful crises and respiratory events. The paper highlights a need for better access to healthcare services for Jamaicans with SCD especially in rural areas of the island. It also reports interesting associations between environmental climatic exposures and health outcomes.

  11. Chemical characterization and sources of personal exposure to fine particulate matter (PM2.5) in the megacity of Guangzhou, China.

    Science.gov (United States)

    Chen, Xiao-Cui; Jahn, Heiko J; Engling, Guenter; Ward, Tony J; Kraemer, Alexander; Ho, Kin-Fai; Yim, S H L; Chan, Chuen-Yu

    2017-12-01

    Concurrent ambient and personal measurements of fine particulate matter (PM 2.5 ) were conducted in eight districts of Guangzhou during the winter of 2011. Personal-to-ambient (P-C) relationships of PM 2.5 chemical components were determined and sources of personal PM 2.5 exposures were evaluated using principal component analysis and a mixed-effects model. Water-soluble inorganic ions (e.g., SO 4 2- , NO 3 - , NH 4 + , C 2 O 4 2- ) and anhydrosugars (e.g., levoglucosan, mannosan) exhibited median personal-to-ambient (P/C) ratios personal PM 2.5 were significantly affected by ambient sources. Conversely, elemental carbon (EC) and calcium (Ca 2+ ) showed median P/C ratios greater than unity, illustrating significant impact of local traffic, indoor sources, and/or personal activities on individual's exposure. SO 4 2- displayed very low coefficient of divergence (COD) values coupled with strong P-C correlations, implying a uniform distribution of SO 4 2- in the urban area of Guangzhou. EC, Ca 2+ , and levoglucosan were otherwise heterogeneously distributed across individuals in different districts. Regional air pollution (50.4 ± 0.9%), traffic-related particles (8.6 ± 0.7%), dust-related particles (5.8 ± 0.7%), and biomass burning emissions (2.0 ± 0.2%) were moderate to high positive sources of personal PM 2.5 exposure in Guangzhou. The observed positive and significant contribution of Ca 2+ to personal PM 2.5 exposure, highlighting indoor sources and/or personal activities, were driving factors determining personal exposure to dust-related particles. Considerable discrepancies (COD values ranging from 0.42 to 0.50) were shown between ambient concentrations and personal exposures, indicating caution should be taken when using ambient concentrations as proxies for personal exposures in epidemiological studies. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Work Inside Ocean Freight Containers—Personal Exposure to Off-Gassing Chemicals

    Science.gov (United States)

    Svedberg, Urban

    2013-01-01

    More than 500 million ocean freight container units are shipped annually between countries and continents. Residual levels of fumigants, as well as naturally occurring off-gassing chemicals emanating from the goods, constitute safety risks, which may affect uniformed workers upon entering the container. The aim of this study was to assess workers’ exposure during stripping of containers and is the first study of its kind. First, an experimental tracer gas method was investigated to determine its usefulness to approximate real exposures from gaseous fumigants and off-gassing volatile organic compounds (VOCs). Nitrous oxide was injected and left to distribute in the closed containers. The distribution of the tracer gas and initial (arrival) concentrations of off-gassing volatiles were measured prior to opening the containers. Second, personal exposure (breathing zone) and work zone air monitoring of both tracer gas and VOCs were carried out during stripping. Adsorbent tubes, bag samples, and direct-readings instruments (photoionization detector and Fourier transform infrared spectrometry) were used. The distribution studies with nitrous oxide, and the high correlation between the former and VOCs (r 2 ~ 0.8) during stripping, showed that the tracer gas method may well be used to approximate real exposures in containers. The average breathing zone and work zone concentrations during stripping of naturally ventilated 40-foot containers were 1–7% of the arrival concentrations; however, peaks up to 70% were seen during opening. Even if average exposures during stripping are significantly lower than arrival concentrations, they may still represent serious violations of occupational exposure limits in high-risk containers. The results from this and previous studies illustrate the need to establish practices for the safe handling of ocean freight containers. Until comprehensive recommendations are in place, personnel that need to enter such containers should, in addition

  13. Work inside ocean freight containers--personal exposure to off-gassing chemicals.

    Science.gov (United States)

    Svedberg, Urban; Johanson, Gunnar

    2013-11-01

    More than 500 million ocean freight container units are shipped annually between countries and continents. Residual levels of fumigants, as well as naturally occurring off-gassing chemicals emanating from the goods, constitute safety risks, which may affect uniformed workers upon entering the container. The aim of this study was to assess workers' exposure during stripping of containers and is the first study of its kind. First, an experimental tracer gas method was investigated to determine its usefulness to approximate real exposures from gaseous fumigants and off-gassing volatile organic compounds (VOCs). Nitrous oxide was injected and left to distribute in the closed containers. The distribution of the tracer gas and initial (arrival) concentrations of off-gassing volatiles were measured prior to opening the containers. Second, personal exposure (breathing zone) and work zone air monitoring of both tracer gas and VOCs were carried out during stripping. Adsorbent tubes, bag samples, and direct-readings instruments (photoionization detector and Fourier transform infrared spectrometry) were used. The distribution studies with nitrous oxide, and the high correlation between the former and VOCs (r(2) ~ 0.8) during stripping, showed that the tracer gas method may well be used to approximate real exposures in containers. The average breathing zone and work zone concentrations during stripping of naturally ventilated 40-foot containers were 1-7% of the arrival concentrations; however, peaks up to 70% were seen during opening. Even if average exposures during stripping are significantly lower than arrival concentrations, they may still represent serious violations of occupational exposure limits in high-risk containers. The results from this and previous studies illustrate the need to establish practices for the safe handling of ocean freight containers. Until comprehensive recommendations are in place, personnel that need to enter such containers should, in addition to

  14. Radiation exposure dose on persons engaged in radiation-related industries in Korea

    International Nuclear Information System (INIS)

    Lim, Bong Sik

    2006-01-01

    This study investigated the status of radiation exposure doses since the establishment of the 'Regulations on Safety Management of Diagnostic Radiation Generation Device' in January 6, 1995. The level of radiation exposure in people engaged or having been engaged in radiation-related industries of inspection organizations, educational organization, military units, hospitals, public health centers, businesses, research organizations or clinics over a 5 year period from Jan. 1, 2000 to Dec. 31, 2004 was measured. The 149,205 measurement data of 57,136 workers registered in a measurement organization were analysed in this study. Frequency analysis, a Chi-square test, Chi-square trend test, and ANOVA was used for data analysis. Among 57,136 men were 40,870 (71.5%). 50.3% of them were radiologic technologists, otherwise medical doctors (22.7%), nurse (2.9%) and others (24.1%). The average of depth radiation and surface radiation during the 5-year period were found to decrease each year. Both the depth radiation and surface radiation exposure were significantly higher in males, in older age groups, in radiological technologists of occupation. The departments of nuclear medicine had the highest exposure of both depth and surface radiation of the divisions of labor. There were 1.98 and 2.57 per 1,000 person-year were exposed more than 20 mSv (limit recommended by International Commission on Radiological Protection) in depth and surface radiation consequently. The total exposure per worker was significantly decreased by year. But Careful awareness is needed for the workers who exposed over 20 mSv per year. In order to minimize exposure to radiation, each person engaged in a radiation-related industry must adhere to the individual safety management guidelines more thoroughly. In addition, systematic education and continuous guidance aimed at increasing the awareness of safety must be provided

  15. Biological Effects of Low-Dose Exposure

    CERN Document Server

    Komochkov, M M

    2000-01-01

    On the basis of the two-protection reaction model an analysis of stochastic radiobiological effects of low-dose exposure of different biological objects has been carried out. The stochastic effects are the results published in the last decade: epidemiological studies of human cancer mortality, the yield of thymocyte apoptosis of mice and different types of chromosomal aberrations. The results of the analysis show that as dependent upon the nature of biological object, spontanous effect, exposure conditions and radiation type one or another form dose - effect relationship is realized: downwards concave, near to linear and upwards concave with the effect of hormesis included. This result testifies to the incomplete conformity of studied effects of 1990 ICRP recomendations based on the linear no-threshold hypothesis about dose - effect relationship. Because of this the methodology of radiation risk estimation recomended by ICRP needs more precisian and such quantity as collective dose ought to be classified into...

  16. Health effects of biomass exposure

    International Nuclear Information System (INIS)

    Rastogi, S.K.; Husain, Tanveer

    1993-01-01

    Biomass fuels such as coal, wood, crop residues, kerosene oil and dung-cakes meet the energy needs in the household sector in India and other developing countries. Crop residues and dung-cakes are largely used in rural areas, whereas wood forms the major source of fuel in urban as well as rural areas. Combustion of these fuels produces various kinds of poisonous gases such as CO, smoke, nitrogen dioxide, polycyclic aromatic hydrocarbons and respirable particulates. These gases are released in the domestic environment and they pollute the indoor air. The women and children are the one who suffer most from this air pollution. This results into a variety of health problems principally pertaining to respiratory system among the women and children. Studies on this aspect are reviewed. They point towards the positive relationship between biomass smoke and various health effects, particularly respiratory diseases. Need for research on the ways to prevent pollution due to biomass and resultant health hazards is emphasised. (M.G.B.). 25 refs., 2 tabs

  17. Validity of at home model predictions as a proxy for personal exposure to radiofrequency electromagnetic fields from mobile phone base stations.

    Science.gov (United States)

    Martens, Astrid L; Bolte, John F B; Beekhuizen, Johan; Kromhout, Hans; Smid, Tjabe; Vermeulen, Roel C H

    2015-10-01

    Epidemiological studies on the potential health effects of RF-EMF from mobile phone base stations require efficient and accurate exposure assessment methods. Previous studies have demonstrated that the 3D geospatial model NISMap is able to rank locations by indoor and outdoor RF-EMF exposure levels. This study extends on previous work by evaluating the suitability of using NISMap to estimate indoor RF-EMF exposure levels at home as a proxy for personal exposure to RF-EMF from mobile phone base stations. For 93 individuals in the Netherlands we measured personal exposure to RF-EMF from mobile phone base stations during a 24h period using an EME-SPY 121 exposimeter. Each individual kept a diary from which we extracted the time spent at home and in the bedroom. We used NISMap to model exposure at the home address of the participant (at bedroom height). We then compared model predictions with measurements for the 24h period, when at home, and in the bedroom by the Spearman correlation coefficient (rsp) and by calculating specificity and sensitivity using the 90th percentile of the exposure distribution as a cutpoint for high exposure. We found a low to moderate rsp of 0.36 for the 24h period, 0.51 for measurements at home, and 0.41 for measurements in the bedroom. The specificity was high (0.9) but with a low sensitivity (0.3). These results indicate that a meaningful ranking of personal RF-EMF can be achieved, even though the correlation between model predictions and 24h personal RF-EMF measurements is lower than with at home measurements. However, the use of at home RF-EMF field predictions from mobile phone base stations in epidemiological studies leads to significant exposure misclassification that will result in a loss of statistical power to detect health effects. Copyright © 2015 Elsevier Inc. All rights reserved.

  18. Adverse effects of e-cigarette exposures.

    Science.gov (United States)

    Cantrell, F Lee

    2014-06-01

    In 2007, a new source of nicotine exposure was introduced to the United States market, the electronic cigarette (ECIG) or "e-cigarette". Since then, the USA ECIG market has been doubling annually. Despite their widespread popularity, there is a paucity of existing data regarding ECIG toxicity. We report the experience of a statewide poison system. The database of a statewide poison system was queried for human ECIG exposures from 2010 (when Poisindex code first generated) through 2012. Year, age, manner and route of exposure, estimate exposure amount, product concentration, if evaluated at healthcare facility and symptoms were recorded. A total of 35 cases were identified--4 in 2010, 12 in 2011, 19 in 2012. Age range 8 months-60 years. Reported symptoms were mild and transient. Five patients were evaluated in an emergency department and none were admitted. Product concentrations ranged from 4 to 30 mg of nicotine per ml. Poison centers are likely to see an increase in exposures to ECIG given their growing popularity. Our modest results suggest that adverse effects and accidental exposures to ECIG cartridges are unlikely to result in serious toxicity.

  19. Household air pollution and personal exposure to nitrated and oxygenated polycyclic aromatics (PAHs) in rural households: Influence of household cooking energies.

    Science.gov (United States)

    Chen, Y; Du, W; Shen, G; Zhuo, S; Zhu, X; Shen, H; Huang, Y; Su, S; Lin, N; Pei, L; Zheng, X; Wu, J; Duan, Y; Wang, X; Liu, W; Wong, M; Tao, S

    2017-01-01

    Residential solid fuels are widely consumed in rural China, contributing to severe household air pollution for many products of incomplete combustion, such as polycyclic aromatic hydrocarbons (PAHs) and their polar derivatives. In this study, concentrations of nitrated and oxygenated PAH derivatives (nPAHs and oPAHs) for household and personal air were measured and analyzed for influencing factors like smoking and cooking energy type. Concentrations of nPAHs and oPAHs in kitchens were higher than those in living rooms and in outdoor air. Exposure levels measured by personal samplers were lower than levels in indoor air, but higher than outdoor air levels. With increasing molecular weight, individual compounds tended to be more commonly partitioned to particulate matter (PM); moreover, higher molecular weight nPAHs and oPAHs were preferentially found in finer particles, suggesting a potential for increased health risks. Smoking behavior raised the concentrations of nPAHs and oPAHs in personal air significantly. People who cooked food also had higher personal exposures. Cooking and smoking have a significant interaction effect on personal exposure. Concentrations in kitchens and personal exposure to nPAHs and oPAHs for households using wood and peat were significantly higher than for those using electricity and liquid petroleum gas (LPG). © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  20. Lessons learnt on biases and uncertainties in personal exposure measurement surveys of radiofrequency electromagnetic fields with exposimeters.

    Science.gov (United States)

    Bolte, John F B

    2016-09-01

    Personal exposure measurements of radio frequency electromagnetic fields are important for epidemiological studies and developing prediction models. Minimizing biases and uncertainties and handling spatial and temporal variability are important aspects of these measurements. This paper reviews the lessons learnt from testing the different types of exposimeters and from personal exposure measurement surveys performed between 2005 and 2015. Applying them will improve the comparability and ranking of exposure levels for different microenvironments, activities or (groups of) people, such that epidemiological studies are better capable of finding potential weak correlations with health effects. Over 20 papers have been published on how to prevent biases and minimize uncertainties due to: mechanical errors; design of hardware and software filters; anisotropy; and influence of the body. A number of biases can be corrected for by determining multiplicative correction factors. In addition a good protocol on how to wear the exposimeter, a sufficiently small sampling interval and sufficiently long measurement duration will minimize biases. Corrections to biases are possible for: non-detects through detection limit, erroneous manufacturer calibration and temporal drift. Corrections not deemed necessary, because no significant biases have been observed, are: linearity in response and resolution. Corrections difficult to perform after measurements are for: modulation/duty cycle sensitivity; out of band response aka cross talk; temperature and humidity sensitivity. Corrections not possible to perform after measurements are for: multiple signals detection in one band; flatness of response within a frequency band; anisotropy to waves of different elevation angle. An analysis of 20 microenvironmental surveys showed that early studies using exposimeters with logarithmic detectors, overestimated exposure to signals with bursts, such as in uplink signals from mobile phones and Wi

  1. Modeling of radionuclide transport through rock formations and the resulting radiation exposure of reference persons. Calculations using Asse II parameters

    International Nuclear Information System (INIS)

    Kueppers, Christian; Ustohalova, Veronika; Steinhoff, Mathias

    2012-01-01

    The long-term release of radioactivity into the ground water path cannot be excluded for the radioactive waste repository Asse II. The possible radiological consequences were analyzed using a radio-ecological scenario developed by GRS. A second scenario was developed considering the solubility of radionuclides in salt saturated solutions and retarding/retention effects during the radionuclide transport through the cap rock layers. The modeling of possible radiation exposure was based on the lifestyle habits of reference persons. In Germany the calculation procedure for the prediction of radionuclide release from final repositories is not defined by national standards, the used procedures are based on analogue methods from other radiation protection calculations.

  2. Instruments to assess and measure personal and environmental radiofrequency-electromagnetic field exposures.

    Science.gov (United States)

    Bhatt, Chhavi Raj; Redmayne, Mary; Abramson, Michael J; Benke, Geza

    2016-03-01

    Radiofrequency-electromagnetic field (RF-EMF) exposure of human populations is increasing due to the widespread use of mobile phones and other telecommunication and broadcasting technologies. There are ongoing concerns about potential short- and long-term public health consequences from RF-EMF exposures. To elucidate the RF-EMF exposure-effect relationships, an objective evaluation of the exposures with robust assessment tools is necessary. This review discusses and compares currently available RF-EMF exposure assessment instruments, which can be used in human epidemiological studies. Quantitative assessment instruments are either mobile phone-based (apps/software-modified and hardware-modified) or exposimeters. Each of these tool has its usefulness and limitations. Our review suggests that assessment of RF-EMF exposures can be improved by using these tools compared to the proxy measures of exposure (e.g. questionnaires and billing records). This in turn, could be used to help increase knowledge about RF-EMF exposure induced health effects in human populations.

  3. Instruments to assess and measure personal and environmental radiofrequency-electromagnetic field exposures

    International Nuclear Information System (INIS)

    Bhatt, Chhavi R.; Redmayne, Mary; Abramson, Michael J.; Benke, Geza

    2016-01-01

    Radiofrequency-electromagnetic field (RF-EMF) exposure of human populations is increasing due to the widespread use of mobile phones and other telecommunication and broadcasting technologies. There are ongoing concerns about potential short- and long-term public health consequences from RF-EMF exposures. To elucidate the RF-EMF exposure-effect relationships, an objective evaluation of the exposures with robust assessment tools is necessary. This review discusses and compares currently available RF-EMF exposure assessment instruments, which can be used in human epidemiological studies. Quantitative assessment instruments are either mobile phone-based (apps/software-modified and hardware-modified) or exposimeters. Each of these tool has its usefulness and limitations. Our review suggests that assessment of RF-EMF exposures can be improved by using these tools compared to the proxy measures of exposure (e.g. questionnaires and billing records). This in turn, could be used to help increase knowledge about RF-EMF exposure induced health effects in human populations.

  4. The relationship between occupational exposure to lead and manifestation of cardiovascular complications in persons with arterial hypertension

    International Nuclear Information System (INIS)

    Poreba, Rafal; Gac, Pawel; Poreba, Malgorzata; Andrzejak, Ryszard

    2010-01-01

    The chronic exposure to lead represents a risk factor of arterial hypertension development. Ambulatory blood pressure monitoring is the most prognostically reliable method of measuring of arterial blood pressure. The study is aimed at evaluating the relationship between occupational exposure to lead and manifestation of cardiovascular complications in patients with arterial hypertension. The studies included 73 men (mean age, 54.26 ± 8.17 years) with arterial hypertension, treated with hypotensive drugs: group I-persons occupationally exposed to lead (n = 35) and group II-individuals not exposed to lead (n = 38). An analysis of results obtained during ambulatory blood pressure monitoring disclosed significantly higher values of mean systolic blood pressure, mean blood pressure, pulse pressure, and variability of systolic blood pressure in the group of hypertensive patients occupationally exposed to lead as compared to patients with arterial hypertension but not exposed to lead. The logistic regression showed that a more advanced age, higher concentration of blood zinc protoporphyrin, and a higher mean value of pulse pressure represented independent risk factors of left ventricular hypertrophy in the group of persons with arterial hypertension and chronically exposed to lead (OR age = 1.11; OR ZnPP = 1.32; OR PP = 1,43; p < 0.05). In view of the above data demonstration that occupational exposure to lead represents an independent risk factor of increased pulse pressure may be of key importance in the process of shaping general social awareness as to harmful effects of lead compounds on human health.

  5. Work-related symptoms and dose-response relationships for personal exposures and pulmonary function among woodworkers.

    Science.gov (United States)

    Mandryk, J; Alwis, K U; Hocking, A D

    1999-05-01

    Four sawmills, a wood chipping mill, and five joineries in New South Wales, Australia, were studied for the effects of personal exposure to wood dust, endotoxins. (1-->3)-beta-D-glucans, Gram-negative bacteria, and fungi on lung function among woodworkers. Personal inhalable and respirable dust sampling was carried out. The lung function tests of workers were conducted before and after a workshift. The mean percentage cross-shift decrease in lung function was markedly high for woodworkers compared with the controls. Dose-response relationships among personal exposures and percentage cross-shift decrease in lung function and percentage predicted lung function were more pronounced among joinery workers compared with sawmill and chip mill workers. Woodworkers had markedly high prevalence of regular cough, phlegm, and chronic bronchitis compared with controls. Significant associations were found between percentage cross-shift decrease in FVC and regular phlegm and blocked nose among sawmill and chip mill workers. Both joinery workers and sawmill and chip mill workers showed significant relationships between percentage predicted lung function (FVC, FEV1, FEV1/FVC, FEF25-75%) and respiratory symptoms. Wood dust and biohazards associated with wood dust are potential health hazards and should be controlled.

  6. Repeated cue exposure effects on subjective and physiological indices of chocolate craving

    OpenAIRE

    Van Gucht, Dinska; Vansteenwegen, Debora; Beckers, Tom; Hermans, Dirk; Baeyens, Frank; Van den Bergh, Omer

    2008-01-01

    The aim of this study is to investigate the effects of repeated unreinforced exposure to chocolate cues in persons reporting chocolate craving. Participants in the experimental group (n=40) received 10 consecutive brief exposures to chocolate cues in each of two sessions, separated by 1-3 days. Control participants (n=18) received two exposures at the start and end of each session. Chocolate craving was measured (alternately) through subjective report and the amount of saliva secretion to cho...

  7. Personal exposures to asbestos fibers during brake maintenance of passenger vehicles.

    Science.gov (United States)

    Cely-García, María Fernanda; Sánchez, Mauricio; Breysse, Patrick N; Ramos-Bonilla, Juan P

    2012-11-01

    Brake linings and brake pads are among the asbestos-containing products that are readily available in Colombia. When sold separated from their support, brake linings require extensive manipulation involving several steps that include drilling, countersinking, riveting, bonding, cutting, beveling, and grinding. Without this manipulation, brake linings cannot be installed in a vehicle. The manipulation process may release asbestos fibers, which may expose brake mechanics to the fibers. Three brake repair shops located in Bogotá (Colombia) were sampled for 3 or 4 consecutive days using US National Institute for Occupational Safety and Health (NIOSH) methods 7400 and 7402. Standard procedures for quality control were followed during the sampling process, and asbestos samples were analyzed by an American Industrial Hygiene Association accredited laboratory. Personal samples were collected to assess full-shift and short-term exposures. Area samples were also collected close to the brake-lining manipulation equipment and within office facilities. Activities were documented during the sampling process. Using Phase Contrast Microscopy Equivalent counts to estimate air asbestos concentrations, all personal samples [i.e. 8-h time-weighted averages (TWAs) and 30-min personal samples] were in compliance with the US Occupational Safety and Health Administration standards. Personal asbestos concentrations based on transmission electron microscopy counts were extremely high, ranging from 0.006 to 3.493 f cm(-3) for 8-h TWA and from 0.015 to 8.835 f cm(-3) for 30-min samples. All asbestos fibers detected were chrysotile. Cleaning facilities and grinding linings resulted in the highest asbestos exposures based on transmission electron microscopy counts. There were also some samples that did not comply with the NIOSH's recommended exposure limits. The results indicate that the brake mechanics sampled are exposed to extremely high asbestos concentrations (i.e. based on transmission

  8. Truncated Levy flights and agenda-based mobility are useful for the assessment of personal human exposure

    International Nuclear Information System (INIS)

    Schlink, Uwe; Ragas, Ad M.J.

    2011-01-01

    Receptor-oriented approaches can assess the individual-specific exposure to air pollution. In such an individual-based model we analyse the impact of human mobility to the personal exposure that is perceived by individuals simulated in an exemplified urban area. The mobility models comprise random walk (reference point mobility, RPM), truncated Levy flights (TLF), and agenda-based walk (RPMA). We describe and review the general concepts and provide an inter-comparison of these concepts. Stationary and ergodic behaviour are explained and applied as well as performance criteria for a comparative evaluation of the investigated algorithms. We find that none of the studied algorithm results in purely random trajectories. TLF and RPMA prove to be suitable for human mobility modelling, because they provide conditions for very individual-specific trajectories and exposure. Suggesting these models we demonstrate the plausibility of their results for exposure to air-borne benzene and the combined exposure to benzene and nonane. - Highlights: → Human exposure to air pollutants is influenced by a person's movement in the urban area. → We provide a simulation study of approaches to modelling personal exposure. → Agenda-based models and truncated Levy flights are recommended for exposure assessment. → The procedure is demonstrated for benzene exposure in an urban region. - Truncated Levy flights and agenda-based mobility are useful for the assessment of personal human exposure.

  9. Personal factors influencing agreement between expert and self-reported assessments of an occupational exposure.

    Science.gov (United States)

    Neilson, Heather K; Sass-Kortsak, Andrea; Lou, W Y Wendy; Purdham, James T

    2007-01-01

    This study aimed to identify personal factors associated with expert and respondent agreement on past occupational exposure. Epidemiologic data was collected from 1995 to 1998 in a community-based, case-control study of prostate cancer. Using longest jobs and excluding agreement on "never" exposure, self-reported and expert estimates of ever/ never exposure, by skin or ingestion, to polycyclic aromatic hydrocarbons were compared. Agreement between respondents and the expert was 53.9 percent (N=1,038), with overreporting being more common than underreporting relative to the expert (31.8 percent versus 14.4 percent). In multiple logistic regression models, white-collar occupational status was significantly associated with overreporting (odds ratio [OR] = 0.142; 95 percent confidence interval [CI]: 0.095-0.211; blue-collar versus white-collar), while age was associated with underreporting (OR=1.077; 95 percent CI: 1.043-1.112; one-year increase). Neither job satisfaction nor risk perception appeared to confound other associations. In future studies, overreporting by white-collar workers might be avoided by providing clearer definitions of exposure, whereas elderly respondents may require aids to enhance exposure recall.

  10. Study of the exposures received by the persons involved in the transportation of radioactive materials

    International Nuclear Information System (INIS)

    Hamard, J.; Sousselier, Y.

    1983-01-01

    An important step in the optimization process applied to exposures in the field of the transport of radioactive materials is an accurate inventory of the exposures actually received by the workers. The results of this study underlines that nearly all the doses received are well below the threshold values for the classification of the workers as occasionally exposed and a fortiori as professionally exposed and consequently no personal monitoring should be necessary for them. Thus the inventory of exposures is somewhat difficult as the workers implied in the transport process are not classified as exposed workers and not subject to personnal or collective dosimetry. Therefore a good knowledge of the exposures received during the transport of irradiated fuels should require a systematic follow up of this kind of transport all along their route including a careful dosimetric monitoring of the workers taking part in the transport. On the other hand, the reduction of the doses obtained by increasing the mechanization involves very high monetary costs as compared to the reduction of the detriment. Perhaps a more important reduction of the exposures could be attained by a better protection in the cars or lorries used for the transport of categories A and B packages. But it seems that in the case of the transports, the optimization is applied mainly during the conception and the testing of the packages and only little progress will be possible without involving disproportionated monetary costs. 4 references, 10 tables

  11. Risk of Children’s Dermal Exposure to Galaxolide through Personal Care Products

    Directory of Open Access Journals (Sweden)

    Patrícia Correia

    2015-04-01

    Full Text Available Galaxolide is the most used fragrance since the early 1990s, and it has been largely detected in environmental and biological matrices. This polycyclic musk is present in almost all of our daily products, so the risk of human exposure is substantial, as it had been proved by its detection in human tissues and fluids. Due to the lack of information about the concentrations found in consumer products, monitoring data is needed for exposure assessment purposes. Dermal contact, mostly by personal care products, seems to be the major route of human exposure to galaxolide, and, due to the immaturity of young children’s skin, exposure consequences can be worse in this population. The main objective of this study was to evaluate galaxolide levels in personal care products used by children of Oporto (Portugal, aged 0–5 years, and relate it with consumer habits. Consumer patterns were obtained through 250 questionnaires to caregivers of Oporto children. The 79 most used products were extracted by a dispersive solid phase extraction methodology known as QuEChERS and galaxolide was determined by High Performance Liquid Chromatography (HPLC with fluorescence detection. The concentrations ranged between 0.001 ± 0.001 mg·kg−1, on a baby wipe, and 300.480 ± 8.819 mg·kg−1, on glycerin soap, which may correspond to an estimated daily dermal exposure of 277.10 ± 0.02 µg·day−1 on the population of Oporto children. This value is in the range of the results observed for adults, although no information of toxicological risk for children is available.

  12. Antenatal Exposure of Persons from Belarus Following the Chernobyl Accidents: Neuropsychiatric Aspects

    International Nuclear Information System (INIS)

    Igumnov, S.; Drozdovitch, V.

    2004-01-01

    Ten years follow-up investigation of intellectual development of 250 persons from Belarus exposed in utero following the Chernobyl accident has been conducted. Exposed cohort was compared with a control group of 250 persons in the same age from non and slightly contaminated regions. For each study subject, individual antenatal doses were reconstructed for the following pathways of exposure: (1) internal doses to thyroid gland arising from the intake of ''131 I via inhalation or ingestion; and (2) external doses from radionuclides deposited on the ground. Neuropsychiatry and psychological examinations were performed among persons of both groups at the age 6-7 years, 10-12 years, and 15-16 years. At the age of 6-7 years the persons in the exposed group had a mean full-scale intelligent quotient (IQ) lower than the control group. At the age of 10-12 and 15-16 years there were no statistically significant differences between the two groups. Positive dynamics of intellectual development in persons of both groups has been observed up to age of 15-16 years. No statiscally significant correlation was found in exposed group between individual thyroid dose as well as individual antenatal external dose and IQ at the different ages. In both groups we notice a positive moderate correlation between IQ of persons and the educational level of their parents. We conclude that probably a significant role in the genesis of borderline intellectual functioning and emotional disorders in the exposed group of persons was played by unfavorable factors such as a low educational level of parents, the break of micro social contacts and adaptation difficulties, which appear following the evacuation and relocation from the contaminated areas. (Author) 10 refs-

  13. RADIOFREQUENCY AND MICROWAVE RADIATION HEALTH EFFECTS AND OCCUPATIONAL EXPOSURE

    Directory of Open Access Journals (Sweden)

    Ivana Damnjanović

    2011-12-01

    Full Text Available In the recent years, there have been considerable discussion and concern about the possible hazards of RF/MW radiation. More recently, the growth and development in personal mobile communications have focused attention on the frequencies associated with this technology. A number of studies have examined the health effects of RF/MW electromagnetic fields (EMFs, originating from occupational exposure, hobbies, or residence near the radio or television transmitters. Particularly controversial are the biophysical mechanisms by which these RF fields may affect biological systems. General health effects reviews explore possible carcinogenic, reproductive and neurological effects. Health effects by exposure source have been observed in radar traffic devices, wireless communications with cellular phones, radio transmission, and magnetic resonance imaging (MRI. Several epidemiological surveys have suggested associations with non-specific complaints such as headache, tiredness, sleep disturbance, loss of memory, and dizziness. These findings, which echo reports of illness associated with other types of radiofrequency (RF radiation, relate not only to the use of mobile phones, but also to residence near the mobile phone base stations and other settings involving occupational exposure. The biological effects suggest that some precautions are necessary, and preventive approaches are highly recommended. Further researches are required to give more information about the effects of microwave radiation on our health, especially in occupational setting and professionally exposed workers.

  14. Using Google Location History to track personal exposure to air pollution

    Science.gov (United States)

    Marais, E. A.; Wiedinmyer, C.

    2017-12-01

    Big data is increasingly used in air pollution research to monitor air quality and develop mitigation strategies. Google Location History provides an archive of geolocation and time information from mobile devices that can be used to track personal exposure to air pollution. Here we demonstrate the utility of Google Location History for assessing true exposure of individuals to air pollution hazardous to human health in an increasingly mobile world. We use the GEOS-Chem chemical transport model at coarse resolution (2° × 2.5°; latitude × longitude) to calculate and sample surface concentrations of fine particle mass (PM2.5) and ozone concentrations at the same time and location of each of six volunteers for 2 years (June 2015 to May 2017) and compare this to annual mean PM2.5 and ozone estimated at their postal addresses. The latter is synonymous with Global Burden of Disease studies that use a static population distribution map. We find that mobile PM2.5 is higher than static PM2.5 for most (five out of six) volunteers and can lead to a 10% increase in the risk for ischemic heart disease and stroke mortality. The difference may be more if instead a high resolution CTM or an abundant air quality monitoring network is used. There is tremendous potential to exploit geolocation and time data from mobile devices for cohort health studies and to determine best practices for limiting personal exposure to air pollution.

  15. Professional exposure of medical workers: radiation levels, radiation risk and personal dose monitoring

    International Nuclear Information System (INIS)

    Bai Guang

    2005-01-01

    The application of radiation in the field of medicine is the most active area. Due to the rapid and strong development of intervention radiology at present near 20 years, particularly, the medical workers become a popularize group which most rapid increasing and also receiving the must high of professional exposure dose. Because, inter alias, radiation protection management nag training have not fully follow up, the aware of radioactive protection and appropriate approach have tot fully meet the development and need, the professional exposure dose received by medical workers, especially those being engaged in intervention radiology, are more higher, as well as have not yet fully receiving the complete personal dose monitoring, the medical workers become the population group which should be paid the most attention to. The writer would advice in this paper that all medical workers who being received a professional radiation exposure should pay more attention to the safety and healthy they by is strengthening radiation protection and receiving complete personal dose monitoring. (authors)

  16. Personal exposure to airborne ultrafine particles in the urban area of Milan

    Science.gov (United States)

    Cattaneo, A.; Garramone, G.; Taronna, M.; Peruzzo, C.; Cavallo, D. M.

    2009-02-01

    The relevance of health effects related to ultrafine particles (UFPs; aerodynamic diameter car), indicating that the highest exposure to UFPs can be reached near motorized traffic. The lowest exposures were observed in green areas and in office microenvironments. An appreciable difference between working and non-working days was observed. Concentration patterns and variation by days of the week and time periods appears related to time trends in traffic intensity.

  17. Biological effects on human health due to radiofrequency/microwave exposure

    DEFF Research Database (Denmark)

    Breckenkamp, Jürgen; Berg, Gabriele; Blettner, Maria

    2003-01-01

    We evaluated the methods and results of nine cohort studies dealing with the biological effects on human health from exposure to radiofrequencies/microwaves, published between 1980 and 2002. The size of the cohorts varied between 304 (3,362 person years) and nearly 200,000 persons (2.7 million......, however, inconsistent. The most important limitations of the studies were the lack of measurements referring to past and current exposures and, thus, the unknown details on actual exposure, the use of possibly biased data as well as the lack of adjustment for potential confounders and the use of indirect...

  18. Personal exposure to particulate PAHs and anthraquinone and oxidative DNA damages in humans.

    Science.gov (United States)

    Wei, Yongjie; Han, In-Kyu; Hu, Min; Shao, Min; Zhang, Junfeng Jim; Tang, Xiaoyan

    2010-11-01

    Recent studies suggest that DNA oxidative damage be related to the chemical constituents of ambient particles. The purpose of this study was to examine whether particulate polycyclic aromatic hydrocarbons (PAHs) and quinone-structure chemicals increase body burden of oxidative stress in human exposed to heavy traffic volume. We recruited two nonsmoking security guards who worked at a university campus gate near a heavily trafficked road. Each subject wore a personal air sampler for 24h per day to estimate exposures to 24 PAHs and anthraquinone (AnQ) in PM(2.5). Daily pre- and post-work shift spot urines were collected for 29d from each subject. Urine samples were analyzed for 8-hydroxy-2'-deoxyguanosine (8-OHdG). Additionally, using 19 organic tracers other than 24 PAHs and AnQ, a receptor source apportionment model of chemical mass balance was applied to determine the contributions of sources on the PM: gasoline vehicle, diesel vehicle, coal burning, vegetable debris, cooking, natural gas and biomass burning. The relationship among urinary 8-OHdG, individual PAH, and AnQ was demonstrated as follows: the average urinary concentration of 8-OHdG was increased more than three times after 8-h work-shift than those before the work shift. All the 24 PAH and AnQ levels were positively and significantly associated with the post-work urinary 8-OHdG. The results from source apportionment suggest vehicular emission to be the dominant source of personal exposure to PM(2.5). Our finding indicates that personal air exposures to 24 individual PAHs and AnQ originating from traffic emissions are important in increasing oxidative burdens in human body. Copyright © 2010 Elsevier Ltd. All rights reserved.

  19. The Fee Sensitive Risk Exposures of Project Authorized Person in Hong Kong

    Directory of Open Access Journals (Sweden)

    Sai-On Cheung

    2012-11-01

    Full Text Available Authorized Persons (AP play a critical role in the design and construction of building works in Hong Kong. Under the Building Ordinance, design and construction of building works need to be coordinated and monitored by an AP registered with the Buildings Department. Professionally qualified Architects, Engineers and Surveyors are eligible to register as AP after completing the prescribed assessment. In addition, the project AP is often appointed by the project owner to be the project team leader. In these capacities, a project AP is exposed to various risks. This paper seeks to identify the fee sensitive risk exposures of project APs. Through an ANOVA study, these risks exposures are those due to liabilities under the Building Ordinance at the construction stage, those towards the third parties and the clients.

  20. Sun behaviour and personal UVR exposure among Europeans on short term holidays

    DEFF Research Database (Denmark)

    Petersen, Bibi; Triguero-Mas, Margarita; Maier, Bernhard

    2015-01-01

    Solar ultraviolet radiation (UVR) is known to be the main cause of skin cancer, the incidence of which is rising with national differences across Europe. With this observation study we aimed to determine the impact of nationality on sun behaviour and personal UVR exposure on sun and ski holidays....... 25 Danish and 20 Spanish sun-seekers were observed during a sun holiday in Spain, and 26 Danish and 27 Austrian skiers were observed during a ski holiday in Austria. The participants recorded their location and clothing in diaries. Personal time-logged UVR data were recorded as standard erythema...... doses (SEDs) by an electronic UVR dosimeter worn on the wrist. Danish sun-seekers were outdoors for significantly longer, received significant higher percentages of ambient UVR, and received greater accumulated UVR doses than Spanish sun-seekers. Danish skiers were also outdoors for significantly longer...

  1. The effects of adolescent methamphetamine exposure

    Directory of Open Access Journals (Sweden)

    Jordan M Buck

    2015-04-01

    Full Text Available Methamphetamine use among adolescents is a significant social and public health concern. Despite increased awareness of methamphetamine use among younger people, relatively little research has examined the effects of adolescent methamphetamine use compared to adult use. Thus much remains to be learned about how methamphetamine alters adolescent brain function and behavior. In this article we review recent trends in adolescent methamphetamine use and data examining the effects of adolescent methamphetamine use on the dopaminergic system and behavior in humans and animal models. Future research is warranted to expand our understanding of the effects of adolescent methamphetamine exposure and how those effects differ from those seen in adults.

  2. Microwave radiation - Biological effects and exposure standards

    Energy Technology Data Exchange (ETDEWEB)

    Lindsay, I.R.

    1980-06-01

    The thermal and nonthermal effects of exposure to microwave radiation are discussed and current standards for microwave exposure are examined in light of the proposed use of microwave power transmission from solar power satellites. Effects considered include cataractogenesis at levels above 100 mW/sq cm, and possible reversible disturbances such as headaches, sleeplessness, irritability, fatigue, memory loss, cardiovascular changes and circadian rhythm disturbances at levels less than 10 mW/sq cm. It is pointed out that while the United States and western Europe have adopted exposure standards of 10 mW/sq cm, those adopted in other countries are up to three orders of magnitude more restrictive, as they are based on different principles applied in determining safe limits. Various aspects of the biological effects of microwave transmissions from space are considered in the areas of the protection of personnel working in the vicinity of the rectenna, interactions of the transmitted radiation with cardiac pacemakers, and effects on birds. It is concluded that thresholds for biological effects from short-term microwave radiation are well above the maximal power density of 1 mW/sq cm projected at or beyond the area of exclusion of a rectenna.

  3. Individual monitoring of external exposure in terms of personal dose equivalent, Hp(d)

    International Nuclear Information System (INIS)

    Fantuzzi, E.

    2001-01-01

    The institute for Radiation Protection of ENEA - Bologna has organised a one day-workshop on the subject: Individual monitoring of external exposure in terms of personal dose equivalent, H p (d). The aim of the workshop was the discussion of the new implications and modifications to be expected in the routine individual monitoring of external radiation, due to the issue of the Decree 241/00 (G.U. 31/8/2000) in charge since 01/01/2001. The decree set up in Italian law the standards contained in the European Directive EURATOM 96/29-Basic Standards for the Protection of Health of Workers and the General Public against Dangers arising from Ionizing Radiation. Among others, the definition of the operational quantities for external radiation for personal and environmental monitoring, H p (d) e H * (d) respectively as defined by ICRU (International Commission for Radiation Units and Measurements), requires to update the methods of measurements and calibration of the personal dosemeters and environmental monitors. This report collects the papers presented at the workshop dealing with the Personal Dose Equivalent, H p (d), the conversion coefficients, H p (d)/K a e H p (d)/ , obtained through Monte Carlo calculations published by ICRU and ICRP (International Commission for Radiation Protection), the new calibration procedures and the practical implication in the routine of individual monitoring in terms of H p (d). Eventually, in the last chapter, the answers to Frequently Asked Questions (FAQ) are briefly reported [it

  4. Commuters’ Personal Exposure to Ambient and Indoor Ozone in Athens, Greece

    Directory of Open Access Journals (Sweden)

    Krystallia K. Kalimeri

    2017-07-01

    Full Text Available This pilot study aimed to monitor the residential/office indoor, outdoor, and personal levels of ozone for people living, working, and commuting in Athens, Greece. Participants (16 persons of this study worked at the same place. Passive sampling analysis results did not indicate any limit exceedance (Directive 2008/50/EC: 120 µg/m3, World Health Organization (WHO Air Quality Guidelines 2005: 100 µg/m3. The highest “house-outdoor” concentration was noticed for participants living in the north suburbs of Athens, confirming the photochemical ozone formation at the northern parts of the basin during southwestern prevailing winds. The residential indoor to outdoor ratio (I/O was found to be significantly lower than unity, underlying the outdoor originality of the pollutant. The highest “office-indoor” concentration was observed in a ground-level building, characterized by the extensive use of photocopy machines and printers. Personal ozone levels were positively correlated only with indoor-office concentrations. A clear correlation of personal ozone levels to the time spent by the individuals during moving/staying outdoors was observed. On the other hand, no correlation was observed when focusing only on commuting time, due to the fact that transit time includes both on-foot and in-vehicle time periods, therefore activities associated with increased exposure levels, but also with pollutants removal by recirculating air filtering systems, respectively.

  5. HELLE: Health Effects of Low Level Exposures

    International Nuclear Information System (INIS)

    Schoten, Eert

    1998-01-01

    The Health Council is closely involved in establishing the scientific foundation of exposure limits for substances and radiation in order to protect public health. Through the years, the Council has contributed to the formulation of principles and procedures, both for carcinogenic and for noncarcinogenic agents. As a rule, the discussion with regard to the derivation of health-based recommended exposure limits centers around the appropriateness of extrapolation methods (What can be inferred from data on high exposure levels and on experimental animals?). Generally speaking, there is a lack of direct information on the health effects of low levels of exposure. Effects at these levels cannot usually be detected by means of traditional animal experiments or epidemiological research. The capacity of these analytical instruments to distinguish between ''signal'' and ''noise'' is inadequate in most cases. Annex B of this report contains a brief outline of the difficulties and the established methods for tackling this problem. In spite of this, the hope exists that the posited weak signals, if they are indeed present, can be detected by other means. The search will have to take place on a deeper level. In other words, effort must be made to discover what occurs at underlying levels of biological organization when organisms are exposed to low doses of radiation or substances. Molecular and cell biology provide various methods and techniques which give an insight into the processes within the cell. This results in an increase in the knowledge about the molecular and cellular effects of exposure to agents, or stated differently, the working mechanisms which form the basis of the health effects. Last year, the Health Council considered that the time was ripe to take stock of the state of knowledge in this field. To this end, an international working conference was held from 19 to 21 October 1997, entitled ''Health Effects of Low Level Exposures: Scientific Developments and

  6. Effects of dysthymia on personality assessment.

    Science.gov (United States)

    Lecic-Tosevski, D; Divac-Jovanovic, M

    1996-01-01

    Twenty-eight dysthymic patients (82.1% with personality disorders) were investigated with questionnaires for personality and depression before and after treatment. When in asymptomatic state, defined by clinical criteria and HAM-D score 6 or lower, the personality profile of 15 patients (group I) was significantly changed from the one before treatment (avoidant, passive-aggressive, borderline and schizotypal dimensions were lower, and narcissistic dimension higher [P personality dimension. The second group manifested a permanent characterological affective syndrome, or a core borderline personality disorder. The limitations of personality assessment during affective episodes are discussed as well as the borderline level of functioning related to it.

  7. Short-term association between personal exposure to noise and heart rate variability: The RECORD MultiSensor Study.

    Science.gov (United States)

    El Aarbaoui, Tarik; Méline, Julie; Brondeel, Ruben; Chaix, Basile

    2017-12-01

    Studies revealed long-term associations between noise exposure and cardiovascular health, but the underlying short-term mechanisms remain uncertain. To explore the concomitant and lagged short-term associations between personal exposure to noise and heart rate variability (HRV) in a real life setting in the Île-de-France region. The RECORD MultiSensor Study collected between July 2014 and June 2015 noise and heart rate data for 75 participants, aged 34-74 years, in their living environments for 7 days using a personal dosimeter and electrocardiography (ECG) sensor on the chest. HRV parameters and noise levels were calculated for 5-min windows. Short-term relationships between noise level and log-transformed HRV parameters were assessed using mixed effects models with a random intercept for participants and a temporal autocorrelation structure, adjusted for heart rate, physical activity (accelerometry), and short-term trends. An increase by one dB(A) of A-weighted equivalent sound pressure level (Leq) was associated with a 0.97% concomitant increase of the Standard deviation of normal to normal intervals (SDNN) (95% CI: 0.92, 1.02), of 2.08% of the Low frequency band power (LF) (95% CI: 1.97, 2.18), of 1.30% of the High frequency band power (HF) (95% CI: 1.17, 1.43), and of 1.16% of the LF/HF ratio (95% CI: 1.10, 1.23). The analysis of lagged exposures to noise adjusted for the concomitant exposure illustrates the dynamic of recovery of the autonomic nervous system. Non-linear associations were documented with all HRV parameters with the exception of HF. Piecewise regression revealed that the association was almost 6 times stronger below than above 65 Leq dB(A) for the SDNN and LF/HF ratio. Personal noise exposure was found to be related to a concomitant increase of the overall HRV, with evidence of imbalance of the autonomic nervous system towards sympathetic activity, a pathway to increased cardiovascular morbidity and mortality. Copyright © 2017 Elsevier Ltd

  8. A Critical Test of Self-Enhancement, Exposure, and Self-Categorization Explanations for First- and Third-Person Perceptions

    Science.gov (United States)

    Reid, Scott A.; Byrne, Sahara; Brundidge, Jennifer S.; Shoham, Mirit D.; Marlow, Mikaela L.

    2007-01-01

    The third-person perception is the tendency for people to believe that others are more influenced by media content than themselves (W. P. Davison, 1983). The current study provides a critical test of self-enhancement, exposure, and self-categorization explanations for first- (i.e., self more influenced than others) and third-person perceptions.…

  9. Home outdoor models for traffic-related air pollutants do not represent personal exposure measurements in Southern California

    International Nuclear Information System (INIS)

    Ducret-Stich, R; Gemperli, A; Ineichen, A; Phuleria, H C; Delfino, R J; Tjoa, T; Wu, J; Liu, L-J S

    2009-01-01

    Recent studies have used measurements or estimates of traffic-related air pollutants at home or school locations to link associations between exposure and health. However, little is known about the validity of these outdoor concentrations as an estimate for personal exposure to traffic. This paper compares modelled outdoor concentrations at home with personal exposure to traffic air pollution of 63 children in two areas in Los Angeles in 2003/2004. Exposure monitoring consisted of sixteen 10-day monitoring runs, with each run monitoring 4 subjects concurrently with the active personal DataRAM for particulate matter 25 ), elemental carbon (EC) and organic carbon (OC). One child per run had concurrent indoor/outdoor home monitoring. Measurements at central sites (24-hr PM 25 , EC, OC) were taken daily and concentrations of PM 25 , EC, and OC from traffic sources were calculated using the CALINE4 model for individual residences. We modelled outdoor concentrations of PM 2 5 , EC and OC with multilinear regression including GIS and meteorological parameters and adjusted for auto-correlation between repeated measurements. The model fit (R 2 ) for home outdoor estimates was 0.94, 0.74 and 0.80 for PM 25 , EC and OC, respectively. Comparisons between these outdoor estimates and the personal measurements showed a good agreement for PM 25 (R 2 =0.65-0.70) with a mean bias of -0.7±11.8|ag for the smog receptor area, and 18.9±16.2|ag for the traffic impacted area. However the outdoor estimates were not related to personal exposure for EC (R 2 =0.01-0.29) and OC (R 2 =0.03- 0.14). Conclusions: Predictions of outdoor concentrations can be used as approximations of personal exposure to PM 25 . However, they are not appropriate for estimating personal exposure to traffic-related air pollutants including EC and OC in studies of acute exposure-response relationships.

  10. Neurobehavioural effects of occupational exposure to lead.

    Science.gov (United States)

    Williamson, A M; Teo, R K

    1986-06-01

    A set of neurobehavioural tests selected on the basis of information processing theory was used to study the effect of low level occupational lead exposure on 59 lead workers compared with a matched control group of the same number. Only one of the lead exposed group had a blood lead concentration above the current threshold limit value of 3.81 mumol/l at the time of testing (mean 2.36 mumol/l, range 1.19-3.92 mumol/l) and none had been detected above that level in the previous three years. Nevertheless, most neurobehavioural functions tested showed some impairment in the lead workers. Visual sensory function was affected and, perhaps as a consequence, sustained attention and psychomotor tasks were performed more slowly by the lead exposed group. Cognitive functions were also impaired, with sensory store memory, short term memory, and learning abilities all showing deficits in lead workers. Such cognitive deficits may also be partly due to initial degradation of the visual input. Long term memory performance compared equally with control levels possibly because of development of a compensatory strategy such as rehearsal by the lead exposed subjects. Multiple linear regression analysis relating to lead workers test performance and their lead exposure showed that performance on the sensory store memory test alone was significantly related to exposure. This was probably due to the homogeneity of the lead exposed group with regard to blood lead concentrations and the use of blood lead as a measure of chronic lead exposure.

  11. Neurobehavioural effects of occupational exposure to lead

    Energy Technology Data Exchange (ETDEWEB)

    Williamson, A.M.; Teo, R.K.

    1986-06-01

    A set of neurobehavioural tests selected on the basis of information processing theory was used to study the effect of low level occupational lead exposure on 59 lead workers compared with a matched control group of the same number. Only one of the lead exposed group had a blood lead concentration above the current threshold limit value of 3.81 mumol/l at the time of testing (mean 2.36 mumol/l, range 1.19-3.92 mumol/l) and none had been detected above that level in the previous three years. Nevertheless, most neurobehavioural functions tested showed some impairment in the lead workers. Visual sensory function was affected and, perhaps as a consequence, sustained attention and psychomotor tasks were performed more slowly by the lead exposed group. Cognitive functions were also impaired, with sensory store memory, short term memory, and learning abilities all showing deficits in lead workers. Such cognitive deficits may also be partly due to initial degradation of the visual input. Long term memory performance compared equally with control levels possibly because of development of a compensatory strategy such as rehearsal by the lead exposed subjects. Multiple linear regression analysis relating to lead workers test performance and their lead exposure showed that performance on the sensory store memory test alone was significantly related to exposure. This was probably due to the homogeneity of the lead exposed group with regard to blood lead concentrations and the use of blood lead as a measure of chronic lead exposure.

  12. Career Success: The Effects of Personality.

    Science.gov (United States)

    Lau, Victor P.; Shaffer, Margaret A.

    1999-01-01

    A model based on Bandura's Social Learning Theory proposes the following personality traits as determinants of career success: locus of control, self-monitoring, self-esteem, and optimism, along with job performance and person-to-environment fit. (SK)

  13. Meteorological aspects of benzene transport, dispersion and personal exposure in Valdez, Alaska

    Energy Technology Data Exchange (ETDEWEB)

    Murray, D.R.; Ball, R.J. [TRC Environmental Corp., Windsor, CT (United States)

    1994-12-31

    The Valdez Air Health Study (VAHS) was conducted in Valdez, Alaska to determine the personal exposure of the residential population of Valdez to certain volatile organic compounds (VOCs). The VAHS used the EPA`s Total Exposure Assessment Methodology (TEAM) with continuous meteorology, air quality and intense tracer measurements to monitor personal and indoor/outdoor concentrations of VOCs in the community. The Valdez fjord is the site of the Alyeska Marine Terminal, the largest crude oil loading terminal in the United States, with a maximum capacity of 2.2 million barrels per day. The Alyeska Marine Terminal is the transfer point for Prudhoe Bay crude oil from the pipeline to marine tankers. During 1990, the terminal and marine tankers were estimated to emit approximately 450 metric tonnes/year of benzene to the air at an average throughput of 1.8 million barrels/day while benzene emissions from other sources in the basin were estimated to be approximately 3 tonnes/year.

  14. Patterns and predictors of personal exposure to indoor air pollution from biomass combustion among women and children in rural China

    Energy Technology Data Exchange (ETDEWEB)

    Baumgartner, J. (Univ. of Minnesota. Institute on the Environment, St. Paul, MN (United States)); Patz, J.; Bautista, L.E. (Univ. of Wisconsin. Dept. of Population Health Sciences, Madison, WI (United States)); Schauer, J.J. (Univ. of Wisconsin. Nelson Institute for Environmental Studies, Madison, WI (United States)); Ezzati, M. (MRC-HPA Center for Environment and Health, Dept. of Epidemiology and Biostatistics, School of Public Health, Imperial College London (United Kingdom)); Lu, L.; Cheng, C. (Yunnan Provincial Centers for Disease Control and Prevention, Yunnan (China))

    2011-12-15

    Indoor air pollution (IAP) from domestic biomass combustion is an important health risk factor, yet direct measurements of personal IAP exposure are scarce. We measured 24-h integrated gravimetric exposure to particles <2.5 mum in aerodynamic diameter (particulate matter, PM{sub 2.5}) in 280 adult women and 240 children in rural Yunnan, China. We also measured indoor PM{sub 2.5} concentrations in a random sample of 44 kitchens. The geometric mean winter PM{sub 2.5} exposure among adult women was twice that of summer exposure [117 mug/m3 (95% CI: 107, 128) vs. 55 mug/m3 (95% CI: 49, 62)]. Children's geometric mean exposure in summer was 53 mug/m3 (95% CI: 46, 61). Indoor PM{sub 2.5} concentrations were moderately correlated with women's personal exposure (r = 0.58), but not for children. Ventilation during cooking, cookstove maintenance, and kitchen structure were significant predictors of personal PM{sub 2.5} exposure among women primarily cooking with biomass. These findings can be used to develop exposure assessment models for future epidemiologic research and inform interventions and policies aimed at reducing IAP exposure. (Author)

  15. Tutoring the Tutors: Supporting Effective Personal Tutoring

    Science.gov (United States)

    McFarlane, Kathryn J.

    2016-01-01

    The research into personal tutoring in higher education from a tutor's perspective suggests that tutors lack training in tutoring and may lack clarity as to the purpose and boundaries of the role. This article explores personal tutors' perceptions of their confidence and competence in relation to personal tutoring and identifies strategies that…

  16. Wearable Personal Exhaust Ventilation, WPEV: Improved Indoor Air Quality and Reduced Exposure to Air Exhaled from a Sick Doctor

    DEFF Research Database (Denmark)

    Bolashikov, Zhecho D.; Barova, Maria; Melikov, Arsen K.

    2015-01-01

    pause) and a tidal flow rate of 6 L/min. A second thermal manikin and heated dummy were used to resemble lying patients. Exhaled air by the doctor was mixed with tracer gas to mimic pathogens. The wearable personal exhaust unit was positioned frontally by the mouth of the doctor at three distances: 0.......02, 0.04, and 0.06 m. It was operated at 0.25 or 0.50 L/s under mixing background ventilation at three air changes per hour. The effect of the wearable exhaust unit geometry by modifying the exhaust surface, as well as the posture of the doctor, standing or seated, was also studied. The use...... of the wearable personal exhaust resulted in cleaner air in the room compared to mixing alone at 12 air changes per hour, reducing the exposure of the two patients. The nozzle geometry and posture of the doctor affected the indoor exposure to exhaled air. The high potential to capture exhaled air makes the device...

  17. Personal and ambient exposures to air toxics in Camden, New Jersey.

    Science.gov (United States)

    Lioy, Paul J; Fan, Zhihua; Zhang, Junfeng; Georgopoulos, Panos; Wang, Sheng-Wei; Ohman-Strickland, Pamela; Wu, Xiangmei; Zhu, Xianlei; Harrington, Jason; Tang, Xiaogang; Meng, Qingyu; Jung, Kyung Hwa; Kwon, Jaymin; Hernandez, Marta; Bonnano, Linda; Held, Joann; Neal, John

    2011-08-01

    Personal exposures and ambient concentrations of air toxics were characterized in a pollution "hot spot" and an urban reference site, both in Camden, New Jersey. The hot spot was the city's Waterfront South neighborhood; the reference site was a neighborhood, about 1 km to the east, around the intersection of Copewood and Davis streets. Using personal exposure measurements, residential ambient air measurements, statistical analyses, and exposure modeling, we examined the impact of local industrial and mobile pollution sources, particularly diesel trucks, on personal exposures and ambient concentrations in the two neighborhoods. Presented in the report are details of our study design, sample and data collection methods, data- and model-analysis approaches, and results and key findings of the study. In summary, 107 participants were recruited from nonsmoking households, including 54 from Waterfront South and 53 from the Copewood-Davis area. Personal air samples were collected for 24 hr and measured for 32 target compounds--11 volatile organic compounds (VOCs*), four aldehydes, 16 polycyclic aromatic hydrocarbons (PAHs), and particulate matter (PM) with an aerodynamic diameter 0.6) was found between benzene and MTBE in both locations. These results suggest that automobile exhausts were the main contributors to benzene and MTBE air pollution in both neighborhoods. Formaldehyde and acetaldehyde concentrations were found to be high in both neighborhoods. Mean (+/- SD) concentrations of formaldehyde were 20.2 +/- 19.5 microg/m3 in Waterfront South and 24.8 +/- 20.8 microg/m3 in Copewood-Davis. A similar trend was observed for the two compounds during the saturation-sampling campaigns. The results indicate that mobile sources (i.e., diesel trucks) had a large impact on formaldehyde and acetaldehyde concentrations in both neighborhoods and that both are aldehyde hot spots. The study also showed that PM2.5, aldehydes, BTEX, and MTBE concentrations in both Waterfront South

  18. Advances in the simulation of personal protective equipment for the mitigation of exposure to radioactive particulates

    International Nuclear Information System (INIS)

    Roeterink, M.J.; Kelly, D.G.; Dickson, E.F.G; Corcoran, E.C.

    2014-01-01

    Airborne radioactive particulates represent a significant potential hazard to first responders in nuclear related incidents. Personal protective equipment (PPE), in particular radio-opaque fabrics, can be used to reduce wearer exposure to the emitted radiation, but do not offer complete protection. The objective of this project is to create a realistic dosimetric model of the human arm, protected by a sleeve, which can eventually be developed into a tool to assess the full-body dose imparted to the wearer in the event of radiological particulate exposure. A two-fold approach will be employed whereby: (1) a particulate transport model will be used to determine the regional radioactive particulate concentrations; and (2) these concentration data will then be incorporated into a dosimetric model that will use the Monte Carlo N-Particle (MCNP) transport code to determine the dose imparted to the tissue. Benchmarking experiments will be carried out to validate the results generated by the computer models. Such experimentation will be conducted for both the particulate transport and dosimetric models. Model advancement aims to consider whole body dose and will be invaluable in the development of future radiation exposure policies and procedures. (author)

  19. MRSA colonization and infection among persons with occupational livestock exposure in Europe: Prevalence, preventive options and evidence.

    Science.gov (United States)

    Goerge, Tobias; Lorenz, Marthe Barbara; van Alen, Sarah; Hübner, Nils-Olaf; Becker, Karsten; Köck, Robin

    2017-02-01

    Colonization with livestock-associated Methicillin-resistant Staphylococcusaureus (LA-MRSA) among persons occupationally exposed to pigs, cattle or poultry is very frequent. In Europe, LA-MRSA mostly belong to the clonal lineage CC398. Since colonized persons have an increased risk of developing MRSA infections, defining the burden of work-related infection caused by LA-MRSA CC398 is of interest to exposed personnel, insurance companies and infection control staff. This review summarizes data on the types of occupation-related infections caused by LA-MRSA CC398, the incidence of such infections as well as potential preventive strategies. We identified twelve case reports on infections among livestock-exposed persons. Overall, there is a lack of data describing the incidence of occupation-related infections due to MRSA CC398. Currently, no specific guidance towards the prevention of LA-MRSA CC398 colonization of persons with routine exposure exists. In vitro, MRSA CC398 strains are susceptible (>95%) to mupirocin. Single reports have described effective decolonization of persons carrying LA-MRSA CC398, but long-term success rates are low in case of continuous livestock contact. Overall, the occupational health risk due to LA-MRSA CC398 is not well understood. Currently, prevention of human LA-MRSA CC398 infection is mostly based on the recommendation to perform screening and decolonization therapies prior to elective medical interventions in order to avoid nosocomial infections, but there is no conclusive evidence to perform specific measures aiming to forestall community-acquired infections. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. Narcissistic personality disorder: effect on relationships.

    Science.gov (United States)

    Roark, Sybil V

    Personality disorders, by definition, affect relationships. Narcissistic Personality Disorder can negatively impact relationships in all areas of life: the workplace, the community, and the family. A clear understanding of the types and extent of interpersonal impairment can assist nurses in establishing therapeutic relationships with those diagnosed with Narcissistic Personality Disorder. The purpose of this activity is to examine the negative impact of Narcissistic Personality Disorder on interpersonal relationships. A review of literature connecting Narcissistic Personality Disorder to impairment in relationships. Research findings show that Narcissistic Personality Disorder symptoms and behaviors will negatively impact interpersonal relationships across all areas of life. CONCLUSIONS AND COMMENT: Nurses interact with diverse populations in a variety of settings. Establishment of a therapeutic relationship with individuals who have Narcissistic Personality Disorder can be aided by a clear understanding of the associated relationship issues.

  1. Accuracy and practicality of a portable ozone monitor for personal exposure estimates

    Science.gov (United States)

    Sagona, Jessica A.; Weisel, Clifford P.; Meng, Qingyu

    2018-02-01

    Accurate measurements of personal exposure to atmospheric pollutants such as ozone are important for understanding health risks. We tested a new personal ozone monitor (POM; 2B Technologies) for accuracy, precision, and ease of use. The POM's measurements were compared to simultaneous ozone measurements from a 2B Model 205 monitor and a ThermoScientific 49i monitor, and multiple POMs were placed side-by-side to check precision. Tests were undertaken in a controlled environmental facility, outdoors, and in a private residence. Additionally, ten volunteers wore a POM for five days and answered a questionnaire about its ease of use. The POM measured ozone accurately compared to the 49i ozone monitor, with average relative differences of less than 8%. In the controlled environment tests, the POM's ozone measurements did not change in the presence of additional atmospheric constituents with similar absorption lines to ozone, though there may have been a small decrease in precision and accuracy. Precision between POMs varied by environment (r2 = 0.98 outdoors; r2 = 0.3 to 0.9 in controlled lab conditions). Volunteers reported that the POM was reasonably comfortable to wear, although all reported that they felt that it was too noisy. Overall, the POM is a viable option for personal ozone monitoring.

  2. Exposure is not enough: suppressing stimuli from awareness can abolish the mere exposure effect.

    Science.gov (United States)

    de Zilva, Daniel; Vu, Luke; Newell, Ben R; Pearson, Joel

    2013-01-01

    Passive exposure to neutral stimuli increases subsequent liking of those stimuli--the mere exposure effect. Because of the broad implications for understanding and controlling human preferences, the role of conscious awareness in mere exposure has received much attention. Previous studies have claimed that the mere exposure effect can occur without conscious awareness of the stimuli. In two experiments, we applied a technique new to the mere exposure literature, called continuous flash suppression, to expose stimuli for a controlled duration with and without awareness. To ensure the reliability of the awareness manipulation, awareness was monitored on a trial-by-trial basis. Our results show that under these conditions the mere exposure effect does not occur without conscious awareness. In contrast, only when participants were aware of the stimuli did exposure increase liking and recognition. Together these data are consistent with the idea that the mere exposure effect requires conscious awareness and has important implications for theories of memory and affect.

  3. Personal exposure of graduate students attending the college of natural sciences or social sciences to volatile organic compounds on campus.

    Science.gov (United States)

    Jo, Wan-Kuen; Kim, Jong-Dae

    2010-11-01

    The present study measured the levels of 24 selected volatile organic compounds (VOCs) in the personal air samples obtained from graduate students attending the college of natural sciences (GSNSs) or social science (GSSSs) during their daily activities on campus along with associated indoor and outdoor air samples. In addition, the sources of their personal exposure were characterized using multivariate statistical models. In the personal samples of GSNSs and GSSSs, 16 and 15 different VOCs were always detected, respectively. The personal exposure of five chlorinated hydrocarbons and six aromatics was significantly higher for GSNSs than for GSSSs. Consistently, the indoor levels of these compounds were higher for GSNSs (in research and laboratory rooms) than for GSSSs (in research rooms). However, the personal exposure of two aromatic VOCs (1,2,4- and 1,3,5-trimethylbenzene) was higher for GSSSs. Moreover, the personal exposure of the five chlorinated and six aromatic compounds was significantly correlated with VOC concentrations both in the research and laboratory rooms of GSNSs and with those in the research rooms of GSSSs. For certain VOCs, outdoor sources were also a major contributor to the personal exposure of both GSNSs and GSSSs. The multivariate models identified five factors that accounted for 81% of the total variance and four factors that explained 76% of the total variance. It was further suggested that multiple indoor sources in research rooms such as office equipment, building finishing materials, and air fresheners were the main source for the personal exposure to VOCs for GSNSs, whereas building finishing materials were the main source for GSSSs. Copyright © 2010 Elsevier Ltd. All rights reserved.

  4. Health and societal effects from exposure to fragranced consumer products.

    Science.gov (United States)

    Steinemann, Anne

    2017-03-01

    Fragranced consumer products-such as air fresheners, cleaning supplies, and personal care products- pervade society. This study investigated the occurrence and types of adverse effects associated with exposure to fragranced products in Australia, and opportunities for prevention. Data were collected in June 2016 using an on-line survey with a representative national sample ( n  = 1098). Overall, 33% of Australians report health problems, such as migraine headaches and asthma attacks, when exposed to fragranced products. Of these health effects, more than half (17.1%) could be considered disabling under the Australian Disability Discrimination Act. Additionally, 7.7% of Australians have lost workdays or a job due to illness from fragranced product exposure in the workplace, 16.4% reported health problems when exposed to air fresheners or deodorizers, 15.3% from being in a room after it was cleaned with scented products, and 16.7% would enter but then leave a business as quickly as possible due to fragranced products. About twice as many respondents would prefer that workplaces, health care facilities and professionals, hotels, and airplanes were fragrance-free rather than fragranced. While 73.7% were not aware that fragranced products, even ones called green and organic, emitted hazardous air pollutants, 56.3% would not continue to use a product if they knew it did. This is the first study in Australia to assess the extent of adverse effects associated with exposure to common fragranced products. It provides compelling evidence for the importance and value of reducing fragranced product exposure in order to reduce and prevent adverse health effects and costs.

  5. Health and societal effects from exposure to fragranced consumer products

    Directory of Open Access Journals (Sweden)

    Anne Steinemann

    2017-03-01

    Full Text Available Fragranced consumer products—such as air fresheners, cleaning supplies, and personal care products— pervade society. This study investigated the occurrence and types of adverse effects associated with exposure to fragranced products in Australia, and opportunities for prevention. Data were collected in June 2016 using an on-line survey with a representative national sample (n = 1098. Overall, 33% of Australians report health problems, such as migraine headaches and asthma attacks, when exposed to fragranced products. Of these health effects, more than half (17.1% could be considered disabling under the Australian Disability Discrimination Act. Additionally, 7.7% of Australians have lost workdays or a job due to illness from fragranced product exposure in the workplace, 16.4% reported health problems when exposed to air fresheners or deodorizers, 15.3% from being in a room after it was cleaned with scented products, and 16.7% would enter but then leave a business as quickly as possible due to fragranced products. About twice as many respondents would prefer that workplaces, health care facilities and professionals, hotels, and airplanes were fragrance-free rather than fragranced. While 73.7% were not aware that fragranced products, even ones called green and organic, emitted hazardous air pollutants, 56.3% would not continue to use a product if they knew it did. This is the first study in Australia to assess the extent of adverse effects associated with exposure to common fragranced products. It provides compelling evidence for the importance and value of reducing fragranced product exposure in order to reduce and prevent adverse health effects and costs.

  6. Chemical exposure reduction: Factors impacting on South African herbicide sprayers' personal protective equipment compliance and high risk work practices.

    Science.gov (United States)

    Andrade-Rivas, Federico; Rother, Hanna-Andrea

    2015-10-01

    The high exposure risks of workers to herbicides in low- and middle-income countries is an important public health concern because of the potential resulting negative impacts on workers' health. This study investigated workers' personal protective equipment (PPE) compliance as a risk mitigation measure; particularly workers who apply herbicides for Working for Water (WfW) - a South African invasive alien vegetation control programme. The study aim was to understand workers' low PPE compliance by analysing their risk perceptions of herbicide use, working conditions and socio-cultural context. Research methods included ethnographic observations, informal interviews, visual media, questionnaires and a focus group. Study results indicated that low PPE compliance persists despite workers' awareness of herbicide exposure risks and as a result of the influence from workers' socio-cultural context (i.e. gender dynamics and social status), herbicide risk perceptions and working conditions (i.e. environmental and logistical). Interestingly, teams comprised of mostly women had the highest compliance rate. These findings highlighted that given the complexity of PPE compliance, especially in countries with several economic and social constraints, exposure reduction interventions should not rely solely on PPE use promotion. Instead, other control strategies requiring less worker input for effectiveness should be implemented, such as elimination and substitution of highly hazardous pesticides, and altering application methods. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.

  7. Examining the (in)effectiveness of personalized communication

    NARCIS (Netherlands)

    Maslowska, E.; Smit, E.; van den Putte, B.; Eisend, M.; Langner, T.

    2011-01-01

    Personalized communication has become a very popular marketing strategy, but the research on its effectiveness is still limited. This study examined the persuasiveness of personalized digital newsletters in terms of increased attention, cognitive activity, evaluation, attitude, intention, and

  8. Changes in the Metabolome in Response to Low-Dose Exposure to Environmental Chemicals Used in Personal Care Products during Different Windows of Susceptibility.

    Science.gov (United States)

    Houten, Sander M; Chen, Jia; Belpoggi, Fiorella; Manservisi, Fabiana; Sánchez-Guijo, Alberto; Wudy, Stefan A; Teitelbaum, Susan L

    2016-01-01

    The consequences of ubiquitous exposure to environmental chemicals remain poorly defined. Non-targeted metabolomic profiling is an emerging method to identify biomarkers of the physiological response to such exposures. We investigated the effect of three commonly used ingredients in personal care products, diethyl phthalate (DEP), methylparaben (MPB) and triclosan (TCS), on the blood metabolome of female Sprague-Dawley rats. Animals were treated with low levels of these chemicals comparable to human exposures during prepubertal and pubertal windows as well as chronically from birth to adulthood. Non-targeted metabolomic profiling revealed that most of the variation in the metabolites was associated with developmental stage. The low-dose exposure to DEP, MPB and TCS had a relatively small, but detectable impact on the metabolome. Multiple metabolites that were affected by chemical exposure belonged to the same biochemical pathways including phenol sulfonation and metabolism of pyruvate, lyso-plasmalogens, unsaturated fatty acids and serotonin. Changes in phenol sulfonation and pyruvate metabolism were most pronounced in rats exposed to DEP during the prepubertal period. Our metabolomics analysis demonstrates that human level exposure to personal care product ingredients has detectable effects on the rat metabolome. We highlight specific pathways such as sulfonation that warrant further study.

  9. Can Personal Exposures to Higher Nighttime and Early Morning Temperatures Increase Blood Pressure?

    Science.gov (United States)

    Environmental temperatures are inversely related to BP; however, the effects of short-term temperature changes within a 24-hour period and measured with high accuracy at the personal level have not been described. Fifty-one nonsmoking patients living in the Detroit area had up to...

  10. Analysing the Effectiveness of the Personality Symbols/Icons

    OpenAIRE

    Halim, İpek

    2012-01-01

    Personality symbol can cover all the identifications of the brand. It can be the face or the soul of the company. Their effect on the brand image is huge. The research focuses on calculating the roles and effectives of the personality symbols. It aims to bring in suggestions for developing a successful personality symbols and lists advantages and disadvantages of different types of personality symbols. It does a detailed copy testing. Apart from conducting focus groups to analyse how the targ...

  11. Assessment of personal exposure from radiofrequency-electromagnetic fields in Australia and Belgium using on-body calibrated exposimeters.

    Science.gov (United States)

    Bhatt, Chhavi Raj; Thielens, Arno; Billah, Baki; Redmayne, Mary; Abramson, Michael J; Sim, Malcolm R; Vermeulen, Roel; Martens, Luc; Joseph, Wout; Benke, Geza

    2016-11-01

    The purposes of this study were: i) to demonstrate the assessment of personal exposure from various RF-EMF sources across different microenvironments in Australia and Belgium, with two on-body calibrated exposimeters, in contrast to earlier studies which employed single, non-on-body calibrated exposimeters; ii) to systematically evaluate the performance of the exposimeters using (on-body) calibration and cross-talk measurements; and iii) to compare the exposure levels measured for one site in each of several selected microenvironments in the two countries. A human subject took part in an on-body calibration of the exposimeter in an anechoic chamber. The same subject collected data on personal exposures across 38 microenvironments (19 in each country) situated in urban, suburban and rural regions. Median personal RF-EMF exposures were estimated: i) of all microenvironments, and ii) across each microenvironment, in two countries. The exposures were then compared across similar microenvironments in two countries (17 in each country). The three highest median total exposure levels were: city center (4.33V/m), residential outdoor (urban) (0.75V/m), and a park (0.75V/m) [Australia]; and a tram station (1.95V/m), city center (0.95V/m), and a park (0.90V/m) [Belgium]. The exposures across nine microenvironments in Melbourne, Australia were lower than the exposures across corresponding microenvironments in Ghent, Belgium (p<0.05). The personal exposures across urban microenvironments were higher than those for rural or suburban microenvironments. Similarly, the exposure levels across outdoor microenvironments were higher than those for indoor microenvironments. Copyright © 2016 Elsevier Inc. All rights reserved.

  12. Personal child and mother carbon monoxide exposures and kitchen levels: methods and results from a randomized trial of woodfired chimney cookstoves in Guatemala (RESPIRE).

    Science.gov (United States)

    Smith, Kirk R; McCracken, John P; Thompson, Lisa; Edwards, Rufus; Shields, Kyra N; Canuz, Eduardo; Bruce, Nigel

    2010-07-01

    During the first randomized intervention trial (RESPIRE: Randomized Exposure Study of Pollution Indoors and Respiratory Effects) in air pollution epidemiology, we pioneered application of passive carbon monoxide (CO) diffusion tubes to measure long-term personal exposures to woodsmoke. Here we report on the protocols and validations of the method, trends in personal exposure for mothers and their young children, and the efficacy of the introduced improved chimney stove in reducing personal exposures and kitchen concentrations. Passive diffusion tubes originally developed for industrial hygiene applications were deployed on a quarterly basis to measure 48-hour integrated personal carbon monoxide exposures among 515 children 0-18 months of age and 532 mothers aged 15-55 years and area samples in a subsample of 77 kitchens, in households randomized into control and intervention groups. Instrument comparisons among types of passive diffusion tubes and against a continuous electrochemical CO monitor indicated that tubes responded nonlinearly to CO, and regression calibration was used to reduce this bias. Before stove introduction, the baseline arithmetic (geometric) mean 48-h child (n=270), mother (n=529) and kitchen (n=65) levels were, respectively, 3.4 (2.8), 3.4 (2.8) and 10.2 (8.4) p.p.m. The between-group analysis of the 3355 post-baseline measurements found CO levels to be significantly lower among the intervention group during the trial period: kitchen levels: -90%; mothers: -61%; and children: -52% in geometric means. No significant deterioration in stove effect was observed over the 18 months of surveillance. The reliability of these findings is strengthened by the large sample size made feasible by these unobtrusive and inexpensive tubes, measurement error reduction through instrument calibration, and a randomized, longitudinal study design. These results from the first randomized trial of improved household energy technology in a developing country and

  13. Eliminating the mere exposure effect through changes in context between exposure and test.

    Science.gov (United States)

    de Zilva, Daniel; Mitchell, Chris J; Newell, Ben R

    2013-01-01

    The present study examined the extent to which increased liking of exposed stimuli--the mere exposure effect--is dependent on experiencing the stimuli in the same context in exposure and on test. Participants were repeatedly exposed to pairs of cues (nonsense words) and target stimuli (faces and shapes), and were asked to rate the pleasantness of the target stimuli in a subsequent test phase. Familiar targets were preferred to novel targets-a mere exposure effect was obtained. This preference for familiar targets was disrupted, however, when the cue-target pairings were rearranged between exposure and test, or a novel cue was introduced at test. Overall, the study suggests that the context of exposure and test moderates the mere exposure effect. Liking of stimuli due to exposure is specific to the context of exposure and does not apply to new or familiar but different contexts.

  14. Nanogold – Biological effects and occupational exposure levels

    Directory of Open Access Journals (Sweden)

    Anna Maria Świdwińska-Gajewska

    2017-08-01

    Full Text Available Nanogold has different properties and biological activity compared to metallic gold. It can be applied in many fields, such as medicine, laboratory diagnostics and electronics. Studies on laboratory animals show that nanogold can be absorbed by inhalation and ingestion. It can penetrate deep into the epidermis and dermis, but there is no evidence that it is absorbed through the skin. Gold nanoobjects accumulate mainly in the liver and spleen, but they can also reach other internal organs. Nanogold can cross the blood–brain and blood–placenta barriers. Toxicokinetics of nanogold depends on the particle size, shape and surface charge. In animals exposure to gold nanoparticles via inhalation induces slight changes in the lungs. Exposure to nanogold by the oral route does not cause adverse health effects in rodents. In animals after injection of gold nanoobjects changes in the liver and lungs were observed. Nanogold induced genotoxic effects in cells, but not in animals. No adverse effects on the fetus or reproduction were found. There are no carcinogenicity studies on gold nanoparticles. The mechanism of toxicity may be related to the interaction of gold nanoobjects with proteins and DNA, and it leads to the induction of oxidative stress and genetic material damage. The impact of nanostructures on human health has not yet been fully understood. The person, who works with nanomaterials should exercise extreme caution and apply existing recommendations on the evaluation of nanoobjects exposure. The risk assessment should be the basis for taking appropriate measures to limit potential exposure to nanometals, including nanogold. Med Pr 2017;68(4:545–556

  15. Potential exposures and health effects from spent fuel transportation

    International Nuclear Information System (INIS)

    Sandquist, G.M.; Rogers, V.C.

    1986-01-01

    The radiation exposures and consequent health effects associated with normal operations and accidents during transportation of spent fuel have been analyzed and evaluated. This study was performed for the U.S. Department of Energy (DOE) as contributory data for response to specific public inquires regarding the Draft Environmental Assessments issued by DOE in 1984. Large quantities of spent fuel from power reactors will be shipped by truck and/or rail from the site of generation or temporary storage to nuclear waste repositories. This transportation activity has the potential for increasing radiation exposures and risks above normal background levels in the vicinity of the transportation route. For normal, accident-free transport of spent fuel, radiation exposures arise from both gamma and neutron sources within the spent fuel cask. U.S. regulations limit the radiation dose equivalent rate to 10 millirem per hour at any point 2 meters from the outer lateral surfaces of the transport vehicle. Computer program PATHRAE-T was developed and employed to determine the total, combined dose field. PATHRAE-T was used to estimate the maximum individual doses from rail cask accidents. The maximum individual exposure, primarily due to inhalation, is about 10 rem and occurs about 70 meters downwind. Ground deposited nuclides account for 99 percent of the population dose. The maximum population dose accident could result in about 22 latent health effects for the urban population. The same case rail cask accidents were also evaluated for a maximum water pathway contamination scenario. The nuclide contaminated plume was assumed to be transported over a large reservoir used for domestic and agricultural water. This accident could result in a 63,000 person-rem dose causing about 13 latent health effects in the absence of any natural and industrial processes for nuclide removal from the water

  16. An accurate filter loading correction is essential for assessing personal exposure to black carbon using an Aethalometer.

    Science.gov (United States)

    Good, Nicholas; Mölter, Anna; Peel, Jennifer L; Volckens, John

    2017-07-01

    The AE51 micro-Aethalometer (microAeth) is a popular and useful tool for assessing personal exposure to particulate black carbon (BC). However, few users of the AE51 are aware that its measurements are biased low (by up to 70%) due to the accumulation of BC on the filter substrate over time; previous studies of personal black carbon exposure are likely to have suffered from this bias. Although methods to correct for bias in micro-Aethalometer measurements of particulate black carbon have been proposed, these methods have not been verified in the context of personal exposure assessment. Here, five Aethalometer loading correction equations based on published methods were evaluated. Laboratory-generated aerosols of varying black carbon content (ammonium sulfate, Aquadag and NIST diesel particulate matter) were used to assess the performance of these methods. Filters from a personal exposure assessment study were also analyzed to determine how the correction methods performed for real-world samples. Standard correction equations produced correction factors with root mean square errors of 0.10 to 0.13 and mean bias within ±0.10. An optimized correction equation is also presented, along with sampling recommendations for minimizing bias when assessing personal exposure to BC using the AE51 micro-Aethalometer.

  17. Ambient concentrations and personal exposure to polycyclic aromatic hydrocarbons (PAH) in an urban community with mixed sources of air pollution

    Science.gov (United States)

    ZHU, XIANLEI; FAN, ZHIHUA (TINA); WU, XIANGMEI; JUNG, KYUNG HWA; OHMAN-STRICKLAND, PAMELA; BONANNO, LINDA J.; LIOY, PAUL J.

    2014-01-01

    Assessment of the health risks resulting from exposure to ambient polycyclic aromatic hydrocarbons (PAH) is limited by a lack of environmental exposure data among the general population. This study characterized personal exposure and ambient concentrations of PAH in the Village of Waterfront South (WFS), an urban community with many mixed sources of air toxics in Camden, New Jersey, and CopeWood/Davis Streets (CDS), an urban reference area located ~1 mile east of WFS. A total of 54 and 53 participants were recruited from non-smoking households in WFS and CDS, respectively. In all, 24-h personal and ambient air samples were collected simultaneously in both areas on weekdays and weekends during summer and winter. The ambient PAH concentrations in WFS were either significantly higher than or comparable to those in CDS, indicating the significant impact of local sources on PAH pollution in WFS. Analysis of diagnostic ratios and correlation suggested that diesel truck traffic, municipal waste combustion and industrial combustion were the major sources in WFS. In such an area, ambient air pollution contributed significantly to personal PAH exposure, explaining 44–96% of variability in personal concentrations. This study provides valuable data for examining the impact of local ambient PAH pollution on personal exposure and therefore potential health risks associated with environmental PAH pollution. PMID:21364704

  18. Estimating overall exposure effects for the clustered and censored outcome using random effect Tobit regression models.

    Science.gov (United States)

    Wang, Wei; Griswold, Michael E

    2016-11-30

    The random effect Tobit model is a regression model that accommodates both left- and/or right-censoring and within-cluster dependence of the outcome variable. Regression coefficients of random effect Tobit models have conditional interpretations on a constructed latent dependent variable and do not provide inference of overall exposure effects on the original outcome scale. Marginalized random effects model (MREM) permits likelihood-based estimation of marginal mean parameters for the clustered data. For random effect Tobit models, we extend the MREM to marginalize over both the random effects and the normal space and boundary components of the censored response to estimate overall exposure effects at population level. We also extend the 'Average Predicted Value' method to estimate the model-predicted marginal means for each person under different exposure status in a designated reference group by integrating over the random effects and then use the calculated difference to assess the overall exposure effect. The maximum likelihood estimation is proposed utilizing a quasi-Newton optimization algorithm with Gauss-Hermite quadrature to approximate the integration of the random effects. We use these methods to carefully analyze two real datasets. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  19. Personal inhalation exposure to polycyclic aromatic hydrocarbons and their nitro-derivatives in rural residents in northern Thailand.

    Science.gov (United States)

    Orakij, Walaiporn; Chetiyanukornkul, Thaneeya; Chuesaard, Thanyarat; Kaganoi, Yuichi; Uozaki, Waka; Homma, Chiharu; Boongla, Yaowatat; Tang, Ning; Hayakawa, Kazuichi; Toriba, Akira

    2017-09-18

    A personal inhalation exposure and cancer risk assessment of rural residents in Lampang, Thailand, was conducted for the first time. This highlighted important factors that may be associated with the highest areal incidence of lung cancer. Personal exposure of rural residents to polycyclic aromatic hydrocarbons (PAHs) and their nitro-derivatives (NPAHs) through inhalation of fine particulate matter (PM 2.5 ) was investigated in addition to stationary air sampling in an urban area. The personal exposure of the subjects to PM 2.5 ranged from 44.4 to 316 μg/m 3 , and the concentrations of PAHs (4.2-224 ng/m 3 ) and NPAHs (120-1449 pg/m 3 ) were higher than those at the urban site, indicating that personal exposure was affected by microenvironments through individual activities. The smoking behaviors of the rural residents barely affected their exposure to PAHs and NPAHs compared to other sources. The most important factor concerning the exposure of rural populations to PAHs was cooking activity, especially the use of charcoal open fires. The emission sources for rural residents and urban air were evaluated using diagnostic ratios, 1-nitropyrene/pyrene, and benzo[a]pyrene/benzo[ghi]perylene. Their analyses showed a significant contribution to emission from residents' personal activities in addition to the atmospheric environment. Furthermore, the personal inhalation cancer risks for all rural subjects exceeded the USEPA guideline value, suggesting that the residents have a potentially increased cancer risk. The use of open fires showed the highest cancer risk. A reduction in exposure to air pollutants for the residents could potentially be achieved by using clean fuel such as liquid petroleum gas or electricity for daily cooking.

  20. Personal exposure to metal fume, NO2, and O3 among production welders and non-welders.

    Science.gov (United States)

    Schoonover, Todd; Conroy, Lorraine; Lacey, Steven; Plavka, Julie

    2011-01-01

    The objective of this study was to characterize personal exposures to welding-related metals and gases for production welders and non-welders in a large manufacturing facility. Welding fume metals and irritant gases nitrogen dioxide (NO(2)) and ozone (O(3)) were sampled for thirty-eight workers. Personal exposure air samples for welding fume metals were collected on 37 mm open face cassettes and nitrogen dioxide and ozone exposure samples were collected with diffusive passive samplers. Samples were analyzed for metals using Inductively Coupled Plasma Mass Spectrometry (ICP-MS) and welding fume metal exposure concentrations were defined as the sum of welding-related metals mass per volume of air sampled. Welding fume metal exposures were highly variable among similar types of welding while NO(2) and O(3) exposure were less variable. Welding fume metal exposures were significantly higher 474 μg/m(3) for welders than non-welders 60 μg/m(3) (p=0.001). Welders were exposed to higher concentrations of NO(2) and O(3) than non-welders but the differences were not statistically significant. Welding fume metal exposure concentrations for welders performing gas metal arc welding (GMAW) and shielded metal arc welding (SMAW) were higher than welders performing gas tungsten arc welding (GTAW). Non-welders experienced exposures similar to GTAW welders despite a curtain wall barrier separating welding and non-welding work areas.

  1. Impact of one's own mobile phone in stand-by mode on personal radiofrequency electromagnetic field exposure.

    Science.gov (United States)

    Urbinello, Damiano; Röösli, Martin

    2013-01-01

    When moving around, mobile phones in stand-by mode periodically send data about their positions. The aim of this paper is to evaluate how personal radiofrequency electromagnetic field (RF-EMF) measurements are affected by such location updates. Exposure from a mobile phone handset (uplink) was measured during commuting by using a randomized cross-over study with three different scenarios: disabled mobile phone (reference), an activated dual-band phone and a quad-band phone. In the reference scenario, uplink exposure was highest during train rides (1.19 mW/m(2)) and lowest during car rides in rural areas (0.001 mW/m(2)). In public transports, the impact of one's own mobile phone on personal RF-EMF measurements was not observable because of high background uplink radiation from other people's mobile phone. In a car, uplink exposure with an activated phone was orders of magnitude higher compared with the reference scenario. This study demonstrates that personal RF-EMF exposure is affected by one's own mobile phone in stand-by mode because of its regular location update. Further dosimetric studies should quantify the contribution of location updates to the total RF-EMF exposure in order to clarify whether the duration of mobile phone use, the most common exposure surrogate in the epidemiological RF-EMF research, is actually an adequate exposure proxy.

  2. Subliminal mere exposure: specific, general, and diffuse effects.

    Science.gov (United States)

    Monahan, J L; Murphy, S T; Zajonc, R B

    2000-11-01

    The present research examined the possibility that repeated exposure may simultaneously produce specific and diffuse effects. In Study 1, participants were presented with 5-ms exposures of 25 stimuli each shown once (single-exposure condition) or with five repetitions of 5 stimuli (repeated-exposure condition). Participants in the repeated-exposure condition subsequently rated their own mood more positively than those in the single-exposure condition. Study 2 examined whether affect generated by subliminal repeated exposures transfers to unrelated stimuli. After a subliminal exposure phase, affective reactions to previously exposed stimuli, to new but similar stimuli, and to stimuli from a different category were obtained. Previously exposed stimuli were rated most positively and novel different stimuli least positively. All stimuli were rated more positively in the repeated-exposure condition than in the single-exposure condition. These findings suggest that affect generated by subliminal repeated exposure is sufficiently diffuse to influence ratings of unrelated stimuli and mood.

  3. Effects of Adult Day Care on Daily Stress of Caregivers: A Within-Person Approach

    Science.gov (United States)

    Kim, Kyungmin; Femia, Elia E.; Almeida, David M.; Savla, Jyoti; Molenaar, Peter C. M.

    2011-01-01

    Objectives. This article examined exposure to and appraisal of care-related stressors associated with use of adult day services (ADS) by family caregivers of individuals with dementia. Methods. Using a within-person withdrawal design (A-B-A-B), we compared caregivers’ exposure to and appraisal of behavior problems on days their relative attended and did not attend ADS. Participants were 121 family caregivers enrolling a relative with dementia in an ADS program. Daily assessments were obtained prior to the person's attending ADS for the first time and after 1 and 2 months of attendance on days the person attended and did not attend ADS. Results. Total exposure to stressors and stress appraisals decreased significantly over time on ADS days compared with non-ADS days. Most of this difference was accounted by the time the person with dementia was away from the caregiver, but there were also significant reductions in behavioral problems during the evening and improved sleep immediately following ADS use. Discussion. ADS use lowered caregivers’ exposure to stressors and may improve behavior and sleep for people with dementia on days they have ADS. The study highlights how a within-person design can identify the effects of an intermittent intervention, such as ADS. PMID:21642593

  4. Effects of Personality on Attitudes toward Academic Group Work

    Science.gov (United States)

    Forrester, William R.; Tashchian, Armen

    2010-01-01

    This study investigated the effects of personality on attitudes toward academic group work among a sample of 225 business students. Data were collected using pre-existing scales for measuring personality and attitudes toward academic group work. Specifically, the Neo-FFI scale was used to measure the five personality dimensions of openness,…

  5. [Effects of radiation exposure on human body].

    Science.gov (United States)

    Kamiya, Kenji; Sasatani, Megumi

    2012-03-01

    There are two types of radiation health effect; acute disorder and late on-set disorder. Acute disorder is a deterministic effect that the symptoms appear by exposure above a threshold. Tissues and cells that compose the human body have different radiation sensitivity respectively, and the symptoms appear in order, from highly radiosensitive tissues. The clinical symptoms of acute disorder begin with a decrease in lymphocytes, and then the symptoms appear such as alopecia, skin erythema, hematopoietic damage, gastrointestinal damage, central nervous system damage with increasing radiation dose. Regarding the late on-set disorder, a predominant health effect is the cancer among the symptoms of such as cancer, non-cancer disease and genetic effect. Cancer and genetic effect are recognized as stochastic effects without the threshold. When radiation dose is equal to or more than 100 mSv, it is observed that the cancer risk by radiation exposure increases linearly with an increase in dose. On the other hand, the risk of developing cancer through low-dose radiation exposure, less 100 mSv, has not yet been clarified scientifically. Although uncertainty still remains regarding low level risk estimation, ICRP propound LNT model and conduct radiation protection in accordance with LNT model in the low-dose and low-dose rate radiation from a position of radiation protection. Meanwhile, the mechanism of radiation damage has been gradually clarified. The initial event of radiation-induced diseases is thought to be the damage to genome such as radiation-induced DNA double-strand breaks. Recently, it is clarified that our cells could recognize genome damage and induce the diverse cell response to maintain genome integrity. This phenomenon is called DNA damage response which induces the cell cycle arrest, DNA repair, apoptosis, cell senescence and so on. These responses act in the direction to maintain genome integrity against genome damage, however, the death of large number of

  6. Stimulus threat and exposure context modulate the effect of mere exposure on approach behaviors

    OpenAIRE

    Steven Young; Heather Claypool; Isaiah Jones

    2016-01-01

    Mere-exposure research has found that initially neutral objects made familiar are preferred relative to novel objects. Recent work extends these preference judgments into the behavioral domain by illustrating that mere exposure prompts approach-oriented behavior toward familiar stimuli. However, no investigations have examined the effect of mere exposure on approach-oriented behavior toward threatening stimuli. The current work examines this issue and also explores how exposure context intera...

  7. Effects of experimental lead exposure and the therapeutic effect of ...

    African Journals Online (AJOL)

    Effects of experimental lead exposure and the therapeutic effect of defatted Moringa oleifera seed meal on serum electrolytes levels of Wistar rats. IS Idoko, IC Ugochukwu, SE Abalaka, AM Adamu, PK Columbus, YA Kwabugge, RE Edeh, S Adamu, B Muhammed ...

  8. How Do Stress Exposure and Stress Regulation Relate to Borderline Personality Disorder?

    Science.gov (United States)

    Bourvis, Nadège; Aouidad, Aveline; Cabelguen, Clémence; Cohen, David; Xavier, Jean

    2017-01-01

    Borderline personality disorder (BPD) is a severe and frequent disorder characterized by a pervasive pattern of instability affecting impulse control, emotional regulation, cognitive processing, self-image and interpersonal relationships. Patients' personal histories are often marked by stressful or traumatic experiences, either unique or repeated. Moreover, while clinical signs of the disorder include both chronic and acute features, acute features are mostly triggered by acute stressful situations. Such features include transient cognitive distortion, intense anger, uncontrollable impulsivity, and self-harm behavior - including suicide - and contribute to the burden of the disease. In this paper, we review the various aspects (epidemiological, clinical, and physiological) contributing to the relationship between BDP and stress. In particular, we explore the statistical association between stress exposure and the emergence of BPD while taking into account other psychopathologies, such as post-traumatic stress disorder. Then, the different aspects of stress responses (namely, the phenomenological, behavioral, hormonal, neuro-vegetative and neural responses) are reviewed in BPD patients. Pathophysiological hypotheses are formulated to explain the differences in responses between BPD patients and healthy subjects and their relation to BPD symptoms. Although the pathogenesis remains uncertain, our conclusions seem to reflect a specific biological and neural pattern of altered stress perception and regulation in BPD.

  9. How Do Stress Exposure and Stress Regulation Relate to Borderline Personality Disorder?

    Directory of Open Access Journals (Sweden)

    Nadège Bourvis

    2017-11-01

    Full Text Available Borderline personality disorder (BPD is a severe and frequent disorder characterized by a pervasive pattern of instability affecting impulse control, emotional regulation, cognitive processing, self-image and interpersonal relationships. Patients’ personal histories are often marked by stressful or traumatic experiences, either unique or repeated. Moreover, while clinical signs of the disorder include both chronic and acute features, acute features are mostly triggered by acute stressful situations. Such features include transient cognitive distortion, intense anger, uncontrollable impulsivity, and self-harm behavior – including suicide – and contribute to the burden of the disease. In this paper, we review the various aspects (epidemiological, clinical, and physiological contributing to the relationship between BDP and stress. In particular, we explore the statistical association between stress exposure and the emergence of BPD while taking into account other psychopathologies, such as post-traumatic stress disorder. Then, the different aspects of stress responses (namely, the phenomenological, behavioral, hormonal, neuro-vegetative and neural responses are reviewed in BPD patients. Pathophysiological hypotheses are formulated to explain the differences in responses between BPD patients and healthy subjects and their relation to BPD symptoms. Although the pathogenesis remains uncertain, our conclusions seem to reflect a specific biological and neural pattern of altered stress perception and regulation in BPD.

  10. How Do Stress Exposure and Stress Regulation Relate to Borderline Personality Disorder?

    Science.gov (United States)

    Bourvis, Nadège; Aouidad, Aveline; Cabelguen, Clémence; Cohen, David; Xavier, Jean

    2017-01-01

    Borderline personality disorder (BPD) is a severe and frequent disorder characterized by a pervasive pattern of instability affecting impulse control, emotional regulation, cognitive processing, self-image and interpersonal relationships. Patients’ personal histories are often marked by stressful or traumatic experiences, either unique or repeated. Moreover, while clinical signs of the disorder include both chronic and acute features, acute features are mostly triggered by acute stressful situations. Such features include transient cognitive distortion, intense anger, uncontrollable impulsivity, and self-harm behavior – including suicide – and contribute to the burden of the disease. In this paper, we review the various aspects (epidemiological, clinical, and physiological) contributing to the relationship between BDP and stress. In particular, we explore the statistical association between stress exposure and the emergence of BPD while taking into account other psychopathologies, such as post-traumatic stress disorder. Then, the different aspects of stress responses (namely, the phenomenological, behavioral, hormonal, neuro-vegetative and neural responses) are reviewed in BPD patients. Pathophysiological hypotheses are formulated to explain the differences in responses between BPD patients and healthy subjects and their relation to BPD symptoms. Although the pathogenesis remains uncertain, our conclusions seem to reflect a specific biological and neural pattern of altered stress perception and regulation in BPD. PMID:29250007

  11. Vascular and lung function related to ultrafine and fine particles exposure assessed by personal and indoor monitoring: a cross-sectional study

    DEFF Research Database (Denmark)

    Olsen, Yulia; Karottki, Dorina Gabriela; Jensen, Ditte Marie

    2014-01-01

    -related effects. Methods: Associations between vascular and lung function, inflammation markers and exposure in terms of particle number concentration (PNC; d = 10-300 nm) were studied in a cross-sectional design with personal and home indoor monitoring in the Western Copenhagen Area, Denmark. During 48-h, PNC...... and PM2.5 were monitored in living rooms of 60 homes with 81 non-smoking subjects (30-75 years old), 59 of whom carried personal monitors both when at home and away from home. We measured lung function in terms of the FEV1/FVC ratio, microvascular function (MVF) and pulse amplitude by digital artery...... tonometry, blood pressure and biomarkers of inflammation including C-reactive protein, and leukocyte counts with subdivision in neutrophils, eosinophils, monocytes, and lymphocytes in blood. Results: PNC from personal and stationary home monitoring showed weak correlation (r = 0.15, p = 0.24). Personal UFP...

  12. Agreement of central site measurements and land use regression modeled oxidative potential of PM{sub 2.5} with personal exposure

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Aileen, E-mail: Yang@uu.nl [National Institute for Public Health and the Environment (RIVM), P.O. Box 1, 3720BA Bilthoven (Netherlands); Institute for Risk Assessment Sciences, Division Environmental Epidemiology, Utrecht University, P.O. Box 80.178, 3508TD Utrecht (Netherlands); Hoek, Gerard; Montagne, Denise [Institute for Risk Assessment Sciences, Division Environmental Epidemiology, Utrecht University, P.O. Box 80.178, 3508TD Utrecht (Netherlands); Leseman, Daan L.A.C. [National Institute for Public Health and the Environment (RIVM), P.O. Box 1, 3720BA Bilthoven (Netherlands); Hellack, Bryan [Air Quality & Sustainable Nanotechnology, Institute of Energy and Environmental Technology (IUTA), e.V., Blierheimer Str. 58-60, 47229 Duisburg (Germany); Kuhlbusch, Thomas A.J. [Air Quality & Sustainable Nanotechnology, Institute of Energy and Environmental Technology (IUTA), e.V., Blierheimer Str. 58-60, 47229 Duisburg (Germany); Center for Nanointegration Duisburg-Essen (CENIDE), University Duisburg-Essen, Carl-Benz-Straße 199, 47057 Duisburg (Germany); Cassee, Flemming R. [National Institute for Public Health and the Environment (RIVM), P.O. Box 1, 3720BA Bilthoven (Netherlands); Institute for Risk Assessment Sciences, Division Environmental Epidemiology, Utrecht University, P.O. Box 80.178, 3508TD Utrecht (Netherlands); Brunekreef, Bert [Institute for Risk Assessment Sciences, Division Environmental Epidemiology, Utrecht University, P.O. Box 80.178, 3508TD Utrecht (Netherlands); Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht (Netherlands); Janssen, Nicole A.H. [National Institute for Public Health and the Environment (RIVM), P.O. Box 1, 3720BA Bilthoven (Netherlands)

    2015-07-15

    Oxidative potential (OP) of ambient particulate matter (PM) has been suggested as a health-relevant exposure metric. In order to use OP for exposure assessment, information is needed about how well central site OP measurements and modeled average OP at the home address reflect temporal and spatial variation of personal OP. We collected 96-hour personal, home outdoor and indoor PM{sub 2.5} samples from 15 volunteers living either at traffic, urban or regional background locations in Utrecht, the Netherlands. OP was also measured at one central reference site to account for temporal variations. OP was assessed using electron spin resonance (OP{sup ESR}) and dithiothreitol (OP{sup DTT}). Spatial variation of average OP at the home address was modeled using land use regression (LUR) models. For both OP{sup ESR} and OP{sup DTT}, temporal correlations of central site measurements with home outdoor measurements were high (R>0.75), and moderate to high (R=0.49–0.70) with personal measurements. The LUR model predictions for OP correlated significantly with the home outdoor concentrations for OP{sup DTT} and OP{sup ESR} (R=0.65 and 0.62, respectively). LUR model predictions were moderately correlated with personal OP{sup DTT} measurements (R=0.50). Adjustment for indoor sources, such as vacuum cleaning and absence of fume-hood, improved the temporal and spatial agreement with measured personal exposure for OP{sup ESR}. OP{sup DTT} was not associated with any indoor sources. Our study results support the use of central site OP for exposure assessment of epidemiological studies focusing on short-term health effects. - Highlights: • Oxidative potential (OP) of PM was proposed as a health-relevant exposure metric. • We evaluated the relationship between measured and modeled outdoor and personal OP. • Temporal correlations of central site with personal OP are moderate to high. • Adjusting for indoor sources improved the agreement with personal OP. • Our results

  13. Effects of Personality Traits, Religiousness/ Spirituality on ...

    African Journals Online (AJOL)

    Religiousness Index (IWSRI), and the General Health Questionnaire (GHQ-28) were administered to 412 randomly selected senior secondary school students to evaluate personality traits, spirituality/religiousness, and psychopathology respectively.

  14. Perceptual Performance and the Effective Person

    National Research Council Canada - National Science Library

    Crutchfield, Richard

    1958-01-01

    The Institute of Personality Assessment and Research carried out an extensive psychological assessment of a group of 100 Air Force captains in order to develop a set of procedures which would identify...

  15. Health effect from EMF exposure of Korea population

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Y. S.; Cho, Y. S.; Lee, J. T.; Yup, M. J.; Hong, J. H. [Institute of Environmental and Industrrial Medicine, Hanyang Univ., Seoul (Korea, Republic of)

    2002-07-01

    This study on health effect from EMF exposure was performed from June 2001 to April 2002 to compare changes in melatonin levels in urine of 40 subjects during their normal sleeping hours, to evaluate heart rate, ST segment in ventricular, and ventricular premature beat for cardiac function, to evaluate microwave exposure from cellular phones which may have a potential influence on the electro physiologic function of human brain, and each 20 subjects in occupational and non-occupational group measured personal 24-h continual exposure, using EMDEX(for 40-800Hz, Enertech Consultant, Inc.). An urine samples for analysis of melatonin excretion level were collected 1 times a day(immediately after wake-up) for five days from each subjects and analyzed by radioimmunoassay, HRV-test for relationship between heart rate and EMF exposure was performed heart rate beat using Holter for subjects, and double EEG-test were performed in 10 long-term users of the cellularphones when using and not using them, and a single EEG-test in 10 short-term users of the cellular phones. Each EEG-recording took 40 min consisting of 30 min filed exposure and 10 min measurement. And We estimated the economic value of the potential damage of electromagnetic radiation from cellular phone, and the willingness to pay of people for the study of the radiation damage led by the government, by applying contingent variation method. The results of this study were followed; 1. Personal exposure assessment 2. We showed not significant difference for the subjective average melatonin levels between occupational and non- occupational groups exposed to electromagnetic fields. 3. We showed no difference in the awake EEGs in terms of spectral power density measures between long-term users and short-term users of cellular phones. 4. We found that the economic value of the potential damage by the radiation for a typical cellular phone user is about 20,000 won per year and he would be willing to pay about 1,800 won

  16. EFFECTS OF ARSENIC EXPOSURE IN HUMAN HEALTH

    Directory of Open Access Journals (Sweden)

    Aline Sueli de Lima Rodrigues

    2008-10-01

    Full Text Available In recent years, ingestion of inorganic arsenic from drinking water has emerged as an important public health concern. It enters drinking water supplies from natural deposits in the earth or from agricultural and industrial practices, mainly the mining. The health consequences of chronic arsenic exposure include increased risk for various forms of cancer and numerous pathologic effects, such as cutaneous effects (hyperpigmentation and hyperkeratoses, gastrointestinal effects, vascular effects, diabetes mellitus, and peripheral neuropathy. This way, this study presents through a critical revision of the literature, the more relevant current aspects on the immunological consequences, carcinogenic and resulting genetics of the human intoxication for arsenic. They were identified and analyzed 50 works published on the subject among the years of 1979 and 2008, being used as main sources LILACS-BIREME MEDLINE/Index Medicus, SciELO and PubMed. The specific Arsênio e saúde humana effects of the intoxication for arsenic about the human health are not still completely elucidated. Thus, is possible that this element affects functions still unknown, becoming important the scientificexploration on the subject.

  17. Exposure effects on music preference and recognition.

    Science.gov (United States)

    Peretz, I; Gaudreau, D; Bonnel, A M

    1998-09-01

    In three experiments, the effects of exposure to melodies on their subsequent liking and recognition were explored. In each experiment, the subjects first listened to a set of familiar and unfamiliar melodies in a study phase. In the subsequent test phase, the melodies were repeated, along with a set of distractors matched in familiarity. Half the subjects were required to rate their liking of each melody, and half had to identify the melodies they had heard earlier in the study phase. Repetition of the studied melodies was found to increase liking of the unfamiliar melodies in the affect task and to be best for detection of familiar melodies in the recognition task (Experiments 1, 2, and 3). These memory effects were found to fade at different time delays between study and test in the affect and recognition tasks, with the latter leading to the most persistent effects (Experiment 2). Both study-to-test changes in melody timbre and manipulation of study tasks had a marked impact on recognition and little influence on liking judgments (Experiment 3). Thus, all manipulated variables were found to dissociate the memory effects in the two tasks. The results are consistent with the view that memory effects in the affect and recognition tasks pertain to the implicit and explicit forms of memory, respectively. Part of the results are, however, at variance with the literature on implicit and explicit memory in the auditory domain. Attribution of these differences to the use of musical material is discussed.

  18. Rabies-related knowledge and practices among persons at risk of bat exposures in Thailand.

    Directory of Open Access Journals (Sweden)

    Kis Robertson

    2011-06-01

    Full Text Available BACKGROUND: Rabies is a fatal encephalitis caused by lyssaviruses. Evidence of lyssavirus circulation has recently emerged in Southeast Asian bats. A cross-sectional study was conducted in Thailand to assess rabies-related knowledge and practices among persons regularly exposed to bats and bat habitats. The objectives were to identify deficiencies in rabies awareness, describe the occurrence of bat exposures, and explore factors associated with transdermal bat exposures. METHODS: A survey was administered to a convenience sample of adult guano miners, bat hunters, game wardens, and residents/personnel at Buddhist temples where mass bat roosting occurs. The questionnaire elicited information on demographics, experience with bat exposures, and rabies knowledge. Participants were also asked to describe actions they would take in response to a bat bite as well as actions for a bite from a potentially rabid animal. Bivariate analysis was used to compare responses between groups and multivariable logistic regression was used to explore factors independently associated with being bitten or scratched by a bat. FINDINGS: Of 106 people interviewed, 11 (10% identified bats as a potential source of rabies. A history of a bat bite or scratch was reported by 29 (27%, and 38 (36% stated either that they would do nothing or that they did not know what they would do in response to a bat bite. Guano miners were less likely than other groups to indicate animal bites as a mechanism of rabies transmission (68% vs. 90%, p=0.03 and were less likely to say they would respond appropriately to a bat bite or scratch (61% vs. 27%, p=0.003. Guano mining, bat hunting, and being in a bat cave or roost area more than 5 times a year were associated with history of a bat bite or scratch. CONCLUSIONS: These findings indicate the need for educational outreach to raise awareness of bat rabies, promote exposure prevention, and ensure appropriate health-seeking behaviors for bat

  19. Integrating smart-phone based momentary location tracking with fixed site air quality monitoring for personal exposure assessment.

    Science.gov (United States)

    Su, Jason G; Jerrett, Michael; Meng, Ying-Ying; Pickett, Melissa; Ritz, Beate

    2015-02-15

    Epidemiological studies investigating relationships between environmental exposures from air pollution and health typically use residential addresses as a single point for exposure, while environmental exposures in transit, at work, school or other locations are largely ignored. Personal exposure monitors measure individuals' exposures over time; however, current personal monitors are intrusive and cannot be operated at a large scale over an extended period of time (e.g., for a continuous three months) and can be very costly. In addition, spatial locations typically cannot be identified when only personal monitors are used. In this paper, we piloted a study that applied momentary location tracking services supplied by smart phones to identify an individual's location in space-time for three consecutive months (April 28 to July 28, 2013) using available Wi-Fi networks. Individual exposures in space-time to the traffic-related pollutants Nitrogen Oxides (NOX) were estimated by superimposing an annual mean NOX concentration surface modeled using the Land Use Regression (LUR) modeling technique. Individual's exposures were assigned to stationary (including home, work and other stationary locations) and in-transit (including commute and other travel) locations. For the individual, whose home/work addresses were known and the commute route was fixed, it was found that 95.3% of the time, the individual could be accurately identified in space-time. The ambient concentration estimated at the home location was 21.01 ppb. When indoor/outdoor infiltration, indoor sources of air pollution and time spent outdoors were taken into consideration, the individual's cumulative exposures were 28.59 ppb and 96.49 ppb, assuming a respective indoor/outdoor ratio of 1.33 and 5.00. Integrating momentary location tracking services with fixed-site field monitoring, plus indoor-outdoor air exchange calibration, makes exposure assessment of a very large population over an extended time period

  20. Quantifying human exposure to air pollution - moving from static monitoring to spatio-temporally resolved personal exposure assessment

    DEFF Research Database (Denmark)

    Steinle, Susanne; Reis, Stefan; Sabel, Clive E

    2013-01-01

    exposure studies to accurately assess human health risks. ? We discuss potential and shortcomings of methods and tools with a focus on how their development influences study design. ? We propose a novel conceptual model for integrated health impact assessment of human exposure to air pollutants. ? We......Quantifying human exposure to air pollutants is a challenging task. Ambient concentrations of air pollutants at potentially harmful levels are ubiquitous in urban areas and subject to high spatial and temporal variability. At the same time, every individual has unique activity-patterns. Exposure...... results from multifaceted relationships and interactions between environmental and human systems, adding complexity to the assessment process. Traditionally, approaches to quantify human exposure have relied on pollutant concentrations from fixed air quality network sites and static population...

  1. A comparison of personal exposure to air pollutants in different travel modes on national highways in India.

    Science.gov (United States)

    Kolluru, Soma Sekhara Rao; Patra, Aditya Kumar; Sahu, Satya Prakash

    2018-04-01

    People often travel a long distance on highways to the nearest city for professional/business activities. However, relatively few publications on passenger exposure to pollutants on highways in India or elsewhere are available. The aim of this study was to examine the contribution of different travel modes to passengers' pollutant exposure for a long distance travel on a national highway in India. We measured PM 2.5 and CO exposure levels of the passengers over 200km on a national highway using two portable air monitors, EVM-7 and EPAM-5000. Personal concentration exposures and per min-, per hour-, per trip- and round trip mass exposures for three travel modes were calculated for 9 trips. Association between pollutants and weather variables were evaluated using levels Spearman correlation. ANOVA was carried out to evaluate the influence of travel mode, the timing of trips, temperature and RH on personal exposures. On an average, PM 2.5 personal concentration exposure levels were highest in the car (85.41±61.85μgm -3 ), followed by the bus (75.08±55.39μgm -3 ) and lowest in the car (ac) (54.43±34.09μgm -3 ). In contrast, CO personal exposure was highest in the car (ac) (1.81±1.3ppm). Travel mode explained the highest variability for CO (18.1%), CO 2 (9.9%), PM 2.5 (1.2%) exposures. In-city mass exposures were higher than trip averages; PM 2.5 :1.21-1.22, 1.13-1.19 and 1.03-1.28 times; CO: 1.20-1.57, 1.37-2.10 and 1.76-2.22 times for bus, car and car (ac) respectively. Traveling by car (ac) results in the lowest PM 2.5 exposures, although it exposes the passenger to high CO level. Avoiding national highways passing through cities can reduce up to 25% PM 2.5 and 50% CO mass exposures. This information can be useful for increasing environmental awareness among the passengers and for framing better pollution control strategies on highways. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. Comparing personal alpha dosimetry with the conventional area monitoring-time weighting methods of exposure estimation: a Canadian assessment

    International Nuclear Information System (INIS)

    Balint, A.B.; Viljoen, J.

    1988-01-01

    An experimental personal alpha dosimetry program for monitoring exposures of uranium mining facility workers in Canada has been completed. All licenced operating mining facilities were participating. Dosimetry techniques, description of dosimeters used by licences, performance and problems associated with the implementation of the programme as well as technical and administrative advantages and difficulties experienced are discussed. Area monitoring-time weighting methods used and results obtained to determine individual radon and thoron daughter exposure and exposure results generated by using dosimeters are assessed and compared

  3. Changes in higher mental functions in persons with late sequels of exposure to small ionizing radiation doses

    International Nuclear Information System (INIS)

    Turuspekova, S.

    2002-01-01

    This is a report on the results of studies on the state of higher mental function in individuals with a previous history of exposure to small doses ionizing radiations. The disorders observed are assigned under several groups as follows: dyspraxia, gnostic, visual-spatial agnosia, mnestic, mental processes impairment, neurodynamic. Mnestic and acoustic-gnostical disturbances, and those of the mental processes are rather markedly expressed. Mnestic derangements play a major role in the general pattern of cognitive disorders, being characterized by both modal-specific, and modal-nonspecific features. The topical principle of the classification proposed enables to distinguish the syndrome of middle nonspecific brain structures involvement and the cortical syndromes among the higher mental function disorders, invariably encountered in combination and not isolated. The aforementioned points to the diffuse nature of the neuropsychological disorders, with involvement in the process of both nonspecific and specific structures, characterized by predomination of the frontal and temporal brain cortex sections. Impairment of the higher mental functions in young persons of active age with a past history of exposure to small doses ionizing radiations, necessitate to work out effective measures precluding occurrence and intensification of the cognitive defect. (author)

  4. Personal exposure to airborne ultrafine particles in the urban area of Milan

    International Nuclear Information System (INIS)

    Cattaneo, A; Garramone, G; Taronna, M; Peruzzo, C; Cavallo, D M

    2009-01-01

    The relevance of health effects related to ultrafine particles (UFPs; aerodynamic diameter 5 particles/cm 3 . UFPs measures were divided on the basis of crossed environments or micro-environments, days of the week and day time (hours). The highest measured mean concentrations and data variability were observed during walking time and moving on motorized vehicles (bus and car), indicating that the highest exposure to UFPs can be reached near motorized traffic. The lowest exposures were observed in green areas and in office microenvironments. An appreciable difference between working and non-working days was observed. Concentration patterns and variation by days of the week and time periods appears related to time trends in traffic intensity.

  5. Students' personal traits, violence exposure, family factors, school dynamics and the perpetration of violence in Taiwanese elementary schools.

    Science.gov (United States)

    Chen, Ji-Kang; Astor, Ron Avi

    2011-02-01

    School violence has become an international problem affecting the well-being of students. To date, few studies have examined how school variables mediate between personal and family factors and school violence in the context of elementary schools in Asian cultures. Using a nationally representative sample of 3122 elementary school students in Taiwan, this study examined a theoretical model proposing that negative personal traits, exposure to violence and parental monitoring knowledge have both direct influences as well as indirect influences mediated through school engagement, at-risk peers and poor student-teacher relationships on school violence committed by students against students and teachers. The results of a structural equation modeling analysis provided a good fit for the sample as a whole. The final model accounted for 32% of the variance for student violence against students and 21% for student violence against teachers. The overall findings support the theoretical model proposed in this study. Similar findings were obtained for both male and female students. The study indicated that to reduce school violence more effectively in the context of elementary schools, intervention may exclusively focus on improving students' within-school experiences and the quality of the students' relationships with teachers and school peers.

  6. Personality, depressive symptoms and prior trauma exposure of new recruits at two Metropolitan Police Service academies in South Africa

    Directory of Open Access Journals (Sweden)

    U Subramaney

    2012-12-01

    Full Text Available Background. Police officers are predisposed to trauma exposure. The development of depression and post-traumatic stress disorder (PTSD may be influenced by personality style, prior exposure to traumatic events and prior depression. Objectives. To describe the personality profiles of new Metropolitan Police Service (MPS officers, and to determine the association between personality profiles, trauma exposure and depressive symptoms. Methods. We performed a cross-sectional analysis of 139 new recruits at two MPS academies in South Africa. A questionnaire elucidating traumatic life events and personality profiles was developed using the Millon Clinical Multiaxial Inventory-III (MCMI-III. Depressive symptoms were measured using the Hamilton Depression Rating Scale (HAMD. Results. Almost all subjects (99.3% had previous trauma exposure, most commonly the unexpected death of a loved one and motor vehicle accidents. Prevalence of clinical depression was low (mean HAMD 3.57; standard deviation ±3.37. Personality characteristics revealed a high prevalence of anxiety (64.7%; 95% CI 56.8 - 72.6, depressive clinical patterns (34.5%; 95% CI 26.6 - 42.2, paranoia (33.1 %; 95% CI 26.6 - 42.2 and major depression (10.3%; 95% CI 5.1 - 15.1. There were no significant associations between any of the traumatic events and depressive symptoms, nor were there any significant associations between any of the personality variables and HAMD score (p>0.05. Conclusion. The presence of depressive symptoms among MPS officers was low, with no significant associations between traumatic events, personality variables and depressive symptoms.

  7. A Comparison of "Total Dust" and Inhalable Personal Sampling for Beryllium Exposure

    Energy Technology Data Exchange (ETDEWEB)

    Carter, Colleen M. [Tulane Univ., New Orleans, LA (United States). School of Public Health and Tropical Medicine

    2012-05-09

    In 2009, the American Conference of Governmental Industrial Hygienists (ACGIH) reduced the Beryllium (Be) 8-hr Time Weighted Average Threshold Limit Value (TLV-TWA) from 2.0 μg/m3 to 0.05 μg/m3 with an inhalable 'I' designation in accordance with ACGIH's particle size-selective criterion for inhalable mass. Currently, per the Department of Energy (DOE) requirements, the Lawrence Livermore National Laboratory (LLNL) is following the Occupational Health and Safety Administration (OSHA) Permissible Exposure Limit (PEL) of 2.0 μg/m3 as an 8-hr TWA, which is also the 2005 ACGIH TLV-TWA, and an Action Level (AL) of 0.2 μg/m3 and sampling is performed using the 37mm (total dust) sampling method. Since DOE is considering adopting the newer 2009 TLV guidelines, the goal of this study was to determine if the current method of sampling using the 37mm (total dust) sampler would produce results that are comparable to what would be measured using the IOM (inhalable) sampler specific to the application of high energy explosive work at LLNL's remote experimental test facility at Site 300. Side-by-side personal sampling using the two samplers was performed over an approximately two-week period during chamber re-entry and cleanup procedures following detonation of an explosive assembly containing Beryllium (Be). The average ratio of personal sampling results for the IOM (inhalable) vs. 37-mm (total dust) sampler was 1.1:1 with a P-value of 0.62, indicating that there was no statistically significant difference in the performance of the two samplers. Therefore, for the type of activity monitored during this study, the 37-mm sampling cassette would be considered a suitable alternative to the IOM sampler for collecting inhalable particulate matter, which is important given the many practical and economic advantages that it presents. However, similar comparison studies would be necessary for this conclusion to be

  8. A global framework to model spatial ecosystems exposure to home and personal care chemicals in Asia.

    Science.gov (United States)

    Wannaz, Cedric; Franco, Antonio; Kilgallon, John; Hodges, Juliet; Jolliet, Olivier

    2018-05-01

    This paper analyzes spatially ecosystem exposure to home and personal care (HPC) chemicals, accounting for market data and environmental processes in hydrological water networks, including multi-media fate and transport. We present a global modeling framework built on ScenAT (spatial scenarios of emission), SimpleTreat (sludge treatment plants), and Pangea (spatial multi-scale multimedia fate and transport of chemicals), that we apply across Asia to four chemicals selected to cover a variety of applications, volumes of production and emission, and physico-chemical and environmental fate properties: the anionic surfactant linear alkylbenzene sulphonate (LAS), the antimicrobial triclosan (TCS), the personal care preservative methyl paraben (MeP), and the emollient decamethylcyclopentasiloxane (D5). We present maps of predicted environmental concentrations (PECs) and compare them with monitored values. LAS emission levels and PECs are two to three orders of magnitude greater than for other substances, yet the literature about monitored levels of LAS in Asia is very limited. We observe a good agreement for TCS in freshwater (Pearson r=0.82, for 253 monitored values covering 12 streams), a moderate agreement in general, and a significant model underestimation for MeP in sediments. While most differences could be explained by uncertainty in both chemical/hydrological parameters (DT50 water , DT50 sediments , K oc , f oc , TSS) and monitoring sites (e.g. spatial/temporal design), the underestimation of MeP concentrations in sediments may involve potential natural sources. We illustrate the relevance of local evaluations for short-lived substances in fresh water (LAS, MeP), and their inadequacy for substances with longer half-lives (TCS, D5). This framework constitutes a milestone towards higher tier exposure modeling approaches for identifying areas of higher chemical concentration, and linking large-scale fate modeling with (sub) catchment-scale ecological scenarios; a

  9. Integrating Dialectical Behavior Therapy and Prolonged Exposure to Treat Co-Occurring Borderline Personality Disorder and PTSD: Two Case Studies

    Science.gov (United States)

    Harned, Melanie S.; Linehan, Marsha M.

    2008-01-01

    Despite the high rate of trauma and PTSD among individuals with borderline personality disorder (BPD), no studies have specifically evaluated the treatment of PTSD in a BPD population. These case studies illustrate the use of a protocol based on prolonged exposure therapy that can be integrated into standard dialectical behavior therapy to treat…

  10. Effects of Inconsistent Behaviors on Person Impressions: A Multidimensional Study.

    Science.gov (United States)

    Vonk, Roos

    1995-01-01

    Examined effects of unexpected behavioral information on person impressions. Inconsistency was manipulated with respect to Implicit Personality Theory. Found that behaviors with inconsistent evaluation implications did not affect impressions and that effects of inconsistent information depended on dimension of contrast, valence of initial…

  11. Source apportionment of indoor, outdoor and personal PM2.5 exposure of pregnant women in Barcelona, Spain

    Science.gov (United States)

    Minguillón, M. C.; Schembari, A.; Triguero-Mas, M.; de Nazelle, A.; Dadvand, P.; Figueras, F.; Salvado, J. A.; Grimalt, J. O.; Nieuwenhuijsen, M.; Querol, X.

    2012-11-01

    Exposure to air pollution has been shown to adversely affect foetal development in the case of pregnant women. The present study aims to investigate the PM composition and sources influencing personal exposure of pregnant women in Barcelona. To this end, indoor, outdoor and personal exposure measurements were carried out for a selection of 54 pregnant women between November 2008 and November 2009. PM2.5 samples were collected during two consecutive days and then analysed for black smoke (BS), major and trace elements, and polycyclic aromatic hydrocarbons (PAHs) concentrations. Personal information such as commuting patterns and cosmetics use was also collected. PM2.5 concentrations were higher for personal samples than for indoor and outdoor environments. Indoor, outdoor and personal BS and sulphate concentrations were strongly correlated, although some specific indoor and outdoor sulphate sources may exist. Average trace elements concentrations were similar indoor, outdoor and for personal exposure, but the correlations were moderate for most of them. Most of the PAHs concentrations showed strong correlations indoor-outdoor. A source apportionment analysis of the PM composition data by means of a Positive Matrix Factorization (PMF) resulted in the identification of six sources for the outdoor and indoor environments: secondary sulphate, fueloil + sea salt (characterized by V, Ni, Na and Mg), mineral, cigarette (characterized by K, Ce, Cd, benzo(k)fluoranthene and benzo(ghi)perylene), road traffic (characterized by BS and low weight PAHs), and industrial (characterized by Pb, Sn, Cu, Mn and Fe). For personal exposure two specific sources were found: cosmetics (characterized by abundance of Ca, Li, Ti and Sr and the absence of Al) and train/subway (characterized by Fe, Mn, Cu and Ba). The contribution of the sources varied widely among women, especially for cigarette (from zero to up to 4 μg m-3), train/subway (up to more than 6 μg m-3) and cosmetics (up to more

  12. A Spatial Model of the Mere Exposure Effect.

    Science.gov (United States)

    Fink, Edward L.; And Others

    1989-01-01

    Uses a spatial model to examine the relationship between stimulus exposure, cognition, and affect. Notes that this model accounts for cognitive changes that a stimulus may acquire as a result of exposure. Concludes that the spatial model is useful for evaluating the mere exposure effect and that affective change does not require cognitive change.…

  13. Exposure to mobile telecommunication networks assessed using personal dosimetry and well-being in children and adolescents: the German MobilEe-study.

    Science.gov (United States)

    Thomas, Silke; Kühnlein, Anja; Heinrich, Sabine; Praml, Georg; von Kries, Rüdiger; Radon, Katja

    2008-11-04

    Despite the increase of mobile phone use in the last decade and the growing concern whether mobile telecommunication networks adversely affect health and well-being, only few studies have been published that focussed on children and adolescents. Especially children and adolescents are important in the discussion of adverse health effects because of their possibly higher vulnerability to radio frequency electromagnetic fields. We investigated a possible association between exposure to mobile telecommunication networks and well-being in children and adolescents using personal dosimetry. A population-based sample of 1.498 children and 1.524 adolescents was assembled for the study (response 52%). Participants were randomly selected from the population registries of four Bavarian (South of Germany) cities and towns with different population sizes. During a Computer Assisted Personal Interview data on participants' well-being, socio-demographic characteristics and potential confounder were collected. Acute symptoms were assessed three times during the study day (morning, noon, evening).Using a dosimeter (ESM-140 Maschek Electronics), we obtained an exposure profile over 24 hours for three mobile phone frequency ranges (measurement interval 1 second, limit of determination 0.05 V/m) for each of the participants. Exposure levels over waking hours were summed up and expressed as mean percentage of the ICNIRP (International Commission on Non-Ionizing Radiation Protection) reference level. In comparison to non-participants, parents and adolescents with a higher level of education who possessed a mobile phone and were interested in the topic of possible adverse health effects caused by mobile telecommunication network frequencies were more willing to participate in the study. The median exposure to radio frequency electromagnetic fields of children and adolescents was 0.18% and 0.19% of the ICNIRP reference level respectively. In comparison to previous studies this is one of

  14. Exposure to mobile telecommunication networks assessed using personal dosimetry and well-being in children and adolescents: the German MobilEe-study

    Directory of Open Access Journals (Sweden)

    von Kries Rüdiger

    2008-11-01

    Full Text Available Abstract Background Despite the increase of mobile phone use in the last decade and the growing concern whether mobile telecommunication networks adversely affect health and well-being, only few studies have been published that focussed on children and adolescents. Especially children and adolescents are important in the discussion of adverse health effects because of their possibly higher vulnerability to radio frequency electromagnetic fields. Methods We investigated a possible association between exposure to mobile telecommunication networks and well-being in children and adolescents using personal dosimetry. A population-based sample of 1.498 children and 1.524 adolescents was assembled for the study (response 52%. Participants were randomly selected from the population registries of four Bavarian (South of Germany cities and towns with different population sizes. During a Computer Assisted Personal Interview data on participants' well-being, socio-demographic characteristics and potential confounder were collected. Acute symptoms were assessed three times during the study day (morning, noon, evening. Using a dosimeter (ESM-140 Maschek Electronics, we obtained an exposure profile over 24 hours for three mobile phone frequency ranges (measurement interval 1 second, limit of determination 0.05 V/m for each of the participants. Exposure levels over waking hours were summed up and expressed as mean percentage of the ICNIRP (International Commission on Non-Ionizing Radiation Protection reference level. Results In comparison to non-participants, parents and adolescents with a higher level of education who possessed a mobile phone and were interested in the topic of possible adverse health effects caused by mobile telecommunication network frequencies were more willing to participate in the study. The median exposure to radio frequency electromagnetic fields of children and adolescents was 0.18% and 0.19% of the ICNIRP reference level respectively

  15. Study on the angular dependence of personal exposure dosimeter - Focus on thermoluminescent dosimeter and photoluminescent dosimeter

    International Nuclear Information System (INIS)

    Dong, Kyung-Rae; Kweon, Dae Cheol; Chung, Woon-Kwan; Goo, Eun-Hoe; Dieter, Kevin; Choe, Chong-Hwan

    2011-01-01

    Radiation management departments place more emphasis on the accuracy of measurements than on the increase in the average dose and personal exposure dose from the use of radiation equipment and radioactive isotopes. Although current measurements are taken using devices, such as film badge dosimeters, pocket dosimeters and thermoluminescent dosimeters (TLDs), this study compared the angular dependence between the widely used TLDs and photoluminescent dosimeter (PLDs) in order to present primary data and evaluate the utility of PLD as a new dosimeter device. For X-ray fluoroscopy, a whole body phantom was placed on a table with a setting for the G-I technical factors fixed at a range of approximately 40 cm with a range of ±90 o at an interval scale of 15 o from the center location of an average radiological worker for PLDs (GD-450) and TLDs (Carot). This process was repeated 10 times, and at each time, the cumulative dosage was interpreted from 130 dosimeters using TLDs (UD-710R, Panasonic) and PLDs (FGD-650). The TLD and PLD showed a 52% and 23% decrease in the depth dosage from 0 o to -90 o , respectively. Therefore, PLDs have a lower angular dependence than TLDs.

  16. Recommendations for Guidelines for EMF Personal Exposure Measurements, Rapid Project #4

    Energy Technology Data Exchange (ETDEWEB)

    T. Dan Bracken, Inc.

    1997-08-01

    The purpose of developing guidelines for electric and magnetic field (EMF) personal exposure measurements (lF'EM) is to ensure reliable and comparable data across I?EM studies. Study techniques may vary due to different populations or objectives, but the resulting data should be consistently reported and comparable, to the extent possible. Any guideline must allow creativity by the research-oriented investigator and provide specific guidance to industrial hygienists or other results-oriented investigators, requiring a standard protocol. Recognizing measurement studies with different purposes is an important aspect of these recommendations. The guidelines presented here intend to produce comparable data across studies while remaining flexible. The recommendations for designing and implementing an EMF PEM program describe a three-stage process. The first step is to clearly state the purpose of the PEM program. The next stage addresses the fundamental elements of an EMF PEM study, including an assessment of the scientific and organizational resources that will be required. This process is codified in a written study plan. These stages are described in 1 Section 5 of this report. The third stage of a PEM study involves the design, implementation and documentation of specific procedures and protocols fo~ sampling strategies, selection of measurement parameters; instrumentation, measurement and data collection, data management, data analysis, quality assurance, uncertainty evaluation, and archiving the study methods and results. The methods for designing these elements of an EMF PEM study are described in Section 6: Specific Guidelines for EMF I?EM Study Design.

  17. Exposure to suicide and suicidality in Korea: differential effects across men and women?

    Science.gov (United States)

    Lee, Min-Ah; Kim, Seokho; Shim, Eun-Jung

    2013-05-01

    Little is known about whether exposure to suicide within close social networks is associated with the suicidality in exposed individuals, and potential gender differences regarding this association. This study examines the effect of exposure to suicide on the suicidality in exposed individuals. The data were drawn from the 2009 Korean General Social Survey, a nationally representative interview survey. Suicidality was measured by the suicidality module in the Mini International Neuropsychiatric Interview (MINI), with exposure to suicide being determined by asking about the experience of a failed or completed suicide attempt by a closely related person. Exposure to the suicide of someone close was significantly associated with higher suicidality in exposed individuals. While the effect of a failed attempt became non-significant after controlling for psychological factors, that of exposure to a completed act of suicide remained significant. A subsample analysis by gender indicated a significant gender difference: with control for demographic and psychological factors, exposure to a completed suicide had a significant effect on the suicidality of females only. The effect of exposure to a failed attempt became non-significant both in males and females after controlling for other factors. Findings suggest the necessity of screening for prior exposure to suicide in suicide risk assessment and the need for gender-tailored suicide-prevention strategies.

  18. Monte Carlo simulations of personal exposure in diagnostic radiology and representative part of the body

    International Nuclear Information System (INIS)

    Ragan, P.; Fueloep, M.

    2008-01-01

    The basic requirements for a representative part of the body for placing a personal dosimeter are to provide a reliable approximation of an effective dose for almost all practical situations, independent of type, energy and incident angle of radiation and with prescribed overall accuracy. For quite a lot of situations it is a problem to find such a place, e. g. using a lead apron is a situation where it is important to make a correct decision for placing the personal dosimeter. For the dosimeter on the apron the dose is highly overestimated and the measured dose under the apron underestimates the estimate of the effective dose. To solve the problem can help Monte Carlo simulations using a mathematical phantom of a human body with and without lead apron. Doses in organs and tissues as results of MC simulations are used to determine a fraction of the effective dose for unshielded parts of the body (hands, legs, head, etc. ) in comparison with simulations without the apron. The mathematical phantom of the human body was used for the simulation of a patient and a physician in a geometry, where the physician is at a thigh of the patient and a scattered radiation is impinging obliquely from the front to the left hand of the body of physician. (authors)

  19. Exposure of bakery and pastry apprentices to airborne flour dust using PM2.5 and PM10 personal samplers.

    Science.gov (United States)

    Mounier-Geyssant, Estelle; Barthélemy, Jean-François; Mouchot, Lory; Paris, Christophe; Zmirou-Navier, Denis

    2007-11-01

    This study describes exposure levels of bakery and pastry apprentices to flour dust, a known risk factor of occupational asthma. Questionnaires on work activity were completed by 286 students. Among them, 34 performed a series of two personal exposure measurements using a PM2.5 and PM10 personal sampler during a complete work shift, one during a cold ("winter") period, and the other during a hot ("summer") period. Bakery apprentices experience greater average PM2.5 and PM10 exposures than pastry apprentices (p < 0.006). Exposure values for both particulate fractions are greater in winter (average PM10 values among bakers = 1.10 mg.m-3 [standard deviation: 0.83]) than in summer (0.63 mg.m-3 [0.36]). While complying with current European occupational limit values, these exposures exceed the ACGIH recommendations set to prevent sensitization to flour dust (0.5 mg.m-3). Over half the facilities had no ventilation system. Young bakery apprentices incur substantial exposure to known airways allergens, a situation that might elicit early induction of airways inflammation.

  20. Application of the expanded Creme RIFM consumer exposure model to fragrance ingredients in cosmetic, personal care and air care products.

    Science.gov (United States)

    Safford, B; Api, A M; Barratt, C; Comiskey, D; Ellis, G; McNamara, C; O'Mahony, C; Robison, S; Rose, J; Smith, B; Tozer, S

    2017-06-01

    As part of a joint project between the Research Institute for Fragrance Materials (RIFM) and Creme Global, a Monte Carlo model (here named the Creme RIFM model) has been developed to estimate consumer exposure to ingredients in personal care products. Details of the model produced in Phase 1 of the project have already been published. Further data on habits and practises have been collected which enable the model to estimate consumer exposure from dermal, oral and inhalation routes for 25 product types. . In addition, more accurate concentration data have been obtained which allow levels of fragrance ingredients in these product types to be modelled. Described is the use of this expanded model to estimate aggregate systemic exposure for eight fragrance ingredients. Results are shown for simulated systemic exposure (expressed as μg/kg bw/day) for each fragrance ingredient in each product type, along with simulated aggregate exposure. Highest fragrance exposure generally occurred from use of body lotions, body sprays and hydroalcoholic products. For the fragrances investigated, aggregate exposure calculated using this model was 11.5-25 fold lower than that calculated using deterministic methodology. The Creme RIFM model offers a very comprehensive and powerful tool for estimating aggregate exposure to fragrance ingredients. Copyright © 2017. Published by Elsevier Inc.

  1. Examining the effects of birth order on personality

    OpenAIRE

    Rohrer, Julia M.; Egloff, Boris; Schmukle, Stefan C.

    2015-01-01

    This study examined the long-standing question of whether a person's position among siblings has a lasting impact on that person's life course. Empirical research on the relation between birth order and intelligence has convincingly documented that performances on psychometric intelligence tests decline slightly from firstborns to laterborns. By contrast, the search for birth-order effects on personality has not yet resulted in conclusive findings. We used data from three large national panel...

  2. Epistemological limitation for attributing health effects to natural radiation exposure

    International Nuclear Information System (INIS)

    González, Abel J.

    2010-01-01

    The attribution of health effects to prolonged radiation exposure situations, such as those experienced in nature, is a challenging problem. The paper describes the epistemological limitations for such attribution it demonstrate that in most natural exposure situations, the theory of radiation-related sciences is not capable to provide the scientific evidence that health effects actually occur (or do not occur) and, therefore, that radiation effects are attributable to natural exposure situations and imputable to nature. Radiation exposure at high levels is known to provoke health effects as tissue reactions. If individuals experience these effects they can be attributed to the specific exposure with a high degree of confidence under the following conditions: the dose incurred have been higher that the relevant dose-threshold for the specific effect; and an unequivocal pathological diagnosis is attainable ensuring that possible competing causes have been eliminated. Only under these conditions, the occurrence of the effect may be properly attested and attributed to the exposure. However, even high levels of natural radiation exposure are lower than relevant dose-thresholds for tissue reactions and, therefore, natural radiation exposure is generally unable to cause these type of effects. One exception to this general rule could be situations of high levels of natural radiation exposure that might be sufficient to induce opacities in the lens of the eyes (which could be considered a tissue-reaction type of effect)

  3. Normal mere exposure effect with impaired recognition in Alzheimer's disease.

    Science.gov (United States)

    Willems, Sylvie; Adam, Stéphane; Van der Linden, Martial

    2002-02-01

    We investigated the mere exposure effect and the explicit memory in Alzheimer's disease (AD) patients and elderly control subjects, using unfamiliar faces. During the exposure phase, the subjects estimated the age of briefly flashed faces. The mere exposure effect was examined by presenting pairs of faces (old and new) and asking participants to select the face they liked. The participants were then presented with a forced-choice explicit recognition task. Controls subjects exhibited above-chance preference and recognition scores for old faces. The AD patients also showed the mere exposure effect but no explicit recognition. These results suggest that the processes involved in the mere exposure effect are preserved in AD patients despite their impaired explicit recognition. The results are discussed in terms of Seamon et al.'s (1995) proposal that processes involved in the mere exposure effect are equivalent to those subserving perceptual priming. These processes would depend on extrastriate areas which are relatively preserved in AD patients.

  4. Respiratory effects of commuters' exposure to air pollution in traffic.

    Science.gov (United States)

    Zuurbier, Moniek; Hoek, Gerard; Oldenwening, Marieke; Meliefste, Kees; van den Hazel, Peter; Brunekreef, Bert

    2011-03-01

    Much time is spent in traffic, especially during rush hours, when air pollution concentrations on roads are relatively high. Controlled exposure studies have shown acute respiratory effects of short, high exposures to air pollution from motor vehicles. Acute health effects of lower real-life exposures in traffic are unclear. Exposures of 34 healthy, nonsmoking adult volunteers were repeatedly measured while commuting for 2 hours by bus, car, or bicycle. Particle number (PN), particulate matter (PM2.5 and PM10), and soot exposures were measured. Lung function and airway resistance were measured directly before, directly following, and 6 hours after exposure. Exhaled nitric oxide (NO) was measured directly before and 6 hours after exposure. Inhaled doses were estimated based on monitored heart rates. Mixed models were used to analyze effects of exposure on changes in health parameters after exposure compared with before. PN, PM10, and soot were associated with decreased peak expiratory flow directly following but not 6 hours after exposure. PN doses were associated with decreases in maximum midexpiratory flow and forced expiratory flow (FEV1) 6 hours after exposure, whereas PN and soot exposures were associated with increased maximum midexpiratory flow and FEV1 directly after exposure. PN and soot were associated with increased exhaled NO after car and bus but not bicycle trips. PN was also associated with an increase in airway resistance directly following exposure but not 6 hours later. We found modest effects of 2-hour in-traffic exposure to air pollutants on peak flow, exhaled NO, and airway resistance.

  5. Effect of exposure on health of atomic bomb servivors

    International Nuclear Information System (INIS)

    Fujitomi, Yutaka; Ueno, Yasushi; Nozaki, Tomoko; Kawaguchi, Fujino; Ishida, Setsuyo

    1976-01-01

    The effects of exposure on vital functions of survivors 30 years after exposure were analyzed, including somatic, psychic, and social factors. Of the survivors living in Nagasaki City, a short-distance exposure group (within 1 km, above 925 rad) and a long-distance exposure group (30 km, 0.6 rad) were selected. The questionnaire included acute symptoms at the time of exposure and present subjective symptoms as indicating vital functions, and psychic factors and medical treatment of exposure as social factors. More of the short-distance exposure group complained of decreased vital functions than did those of the long-distance exposure group. Anxiety was mentioned as one of the causes of the present subjective symptoms. It was not thought that there was relationship between the acute symptoms and the present symptoms. A tendency toward decreased hemoglobin was observed in some of the subjects. (Serizawa, K.)

  6. Incarceration and exposure to internally displaced persons camps associated with reproductive rights abuses among sex workers in northern Uganda.

    Science.gov (United States)

    Erickson, Margaret; Goldenberg, Shira M; Akello, Monica; Muzaaya, Godfrey; Nguyen, Paul; Birungi, Josephine; Shannon, Kate

    2017-07-01

    While female sex workers (FSWs) face a high burden of violence and criminalisation, coupled with low access to safe, non-coercive care, little is known about such experiences among FSWs in conflict-affected settings, particularly as they relate to sexual and reproductive health (SRH) and rights. We explored factors associated with lifetime abortions among FSWs in northern Uganda; and separately modelled the independent effect of lifetime exposures to incarceration and living in internally displaced persons (IDP) camps on coerced and unsafe abortions. Analyses are based on a community-based cross-sectional research project in Gulu District, northern Uganda (2011-2012) with The AIDS Support Organization (TASO) Gulu, FSWs, and other community organisations. We conducted questionnaires, sex worker/community-led outreach to sex work venues, and voluntary HIV testing by TASO. Of 400 FSWs, 62 had ever accessed an abortion. In a multivariable model, gendered violence, both childhood mistreatment/or abuse at home [adjusted odds ratio (AOR) 1.96; 95% confidence interval (95% CI) 0.99-3.90] and workplace violence by clients (AOR 3.57; 95% CI 1.31-9.72) were linked to increased experiences of abortion. Lifetime exposure to incarceration retained an independent effect on increased odds of coerced abortion (AOR 5.16; 95% CI 1.39-19.11), and living in IDP camps was positively associated with unsafe abortion (AOR 4.71; 95% CI 1.42-15.61). These results suggest a critical need for removal of legal and social barriers to realising the SRH rights of all women, and ensuring safe, voluntary access to reproductive choice for marginalised and criminalised populations of FSWs. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  7. Mercury Quick Facts: Health Effects of Mercury Exposure

    Science.gov (United States)

    ... 2012 What are the Health Effects of Mercury Exposure? The health effects that can be caused by breathing mercury depend ... they breathe faster and have smaller lungs. Health effects caused by long-term exposure to mercury vapors • • Anxiety • • Excessive shyness • • Anorexia • • Sleeping ...

  8. Validity of self-reported intensity of exposure to second-hand smoke at home against environmental and personal markers.

    Science.gov (United States)

    Martínez-Sánchez, José M; González-Marrón, Adrián; Martín-Sánchez, Juan Carlos; Sureda, Xisca; Fu, Marcela; Pérez-Ortuño, Raúl; Lidón-Moyano, Cristina; Galán, Iñaki; Pascual, José Antonio; Fernández, Esteve

    2017-11-02

    The objective of this study was to assess the validity of two questions about the perception of intensity of exposure to secondhand smoke (SHS) at home using as a reference environmental markers (airborne nicotine and benzene) and biomarkers of exposure (cotinine in saliva and urine). This was a cross-sectional study in a convenience sample of 49 non-smoking volunteers. We found a high correlation between self-reported SHS exposure and airborne nicotine (r sp =0.806, p0.05). In conclusion, the significant correlation of the two questions proposed with environmental markers and personal markers indicates their potential validity to assess exposure to SHS at home. Copyright © 2017 SESPAS. Publicado por Elsevier España, S.L.U. All rights reserved.

  9. Exposure is not enough: suppressing stimuli from awareness can abolish the mere exposure effect.

    Directory of Open Access Journals (Sweden)

    Daniel de Zilva

    Full Text Available Passive exposure to neutral stimuli increases subsequent liking of those stimuli--the mere exposure effect. Because of the broad implications for understanding and controlling human preferences, the role of conscious awareness in mere exposure has received much attention. Previous studies have claimed that the mere exposure effect can occur without conscious awareness of the stimuli. In two experiments, we applied a technique new to the mere exposure literature, called continuous flash suppression, to expose stimuli for a controlled duration with and without awareness. To ensure the reliability of the awareness manipulation, awareness was monitored on a trial-by-trial basis. Our results show that under these conditions the mere exposure effect does not occur without conscious awareness. In contrast, only when participants were aware of the stimuli did exposure increase liking and recognition. Together these data are consistent with the idea that the mere exposure effect requires conscious awareness and has important implications for theories of memory and affect.

  10. Is prevention of acute pesticide poisoning effective and efficient, with Locally Adapted Personal Protective Equipment?

    DEFF Research Database (Denmark)

    Varma, Anshu; Neupane, Dinesh; Ellekilde Bonde, Jens Peter

    2016-01-01

    BACKGROUND: Farmers' risk of pesticide poisoning can be reduced with personal protective equipment but in low-income countries farmers' use of such equipment is limited. OBJECTIVE: To examine the effectiveness and efficiency of Locally Adapted Personal Protective Equipment to reduce organophosphate...... exposure among farmers. METHODS: In a crossover study, 45 male farmers from Chitwan, Nepal, were randomly allocated to work as usual applying organophosphate pesticides wearing Locally Adapted Personal Protective Equipment or Daily Practice Clothing. For seven days before each experiment, each farmer.......08;0.06]. Wearing the Locally Adapted Personal Protective Equipment versus Daily Practice Clothing gave the following results, respectively: comfort 75.6% versus 100%, sense of heat 64.4% versus 31.3%, other problems 44.4% versus 33.3%, likeability 95.6% versus 77.8%. CONCLUSION: We cannot support the expectation...

  11. Stimulus threat and exposure context modulate the effect of mere exposure on approach behaviors

    Directory of Open Access Journals (Sweden)

    Steven Young

    2016-11-01

    Full Text Available Mere-exposure research has found that initially neutral objects made familiar are preferred relative to novel objects. Recent work extends these preference judgments into the behavioral domain by illustrating that mere exposure prompts approach-oriented behavior toward familiar stimuli. However, no investigations have examined the effect of mere exposure on approach-oriented behavior toward threatening stimuli. The current work examines this issue and also explores how exposure context interacts with stimulus threat to influence behavioral tendencies. In two experiments participants were presented with both mere-exposed and novel stimuli and approach speed was assessed. In the first experiment, when stimulus threat was presented in a homogeneous format (i.e., participants viewed exclusively neutral or threatening stimuli, mere-exposure potentiated approach behaviors for both neutral and threatening stimuli. However, in the second experiment, in which stimulus threat was presented in a heterogeneous fashion (i.e., participants viewed both neutral and threatening stimuli, mere exposure facilitated approach only for initially neutral stimuli. These results suggest that mere-exposure effects on approach behaviors are highly context sensitive and depend on both stimulus valence and exposure context. Further implications of these findings for the mere-exposure literature are discussed.

  12. Personal inhalation exposure to polycyclic aromatic hydrocarbons in urban and rural residents in a typical northern city in China.

    Science.gov (United States)

    Duan, X; Wang, B; Zhao, X; Shen, G; Xia, Z; Huang, N; Jiang, Q; Lu, B; Xu, D; Fang, J; Tao, S

    2014-10-01

    Personal inhalation exposure samples were collected and analyzed for polycyclic aromatic hydrocarbons (PAHs) for 126 selected volunteers during heating and non-heating seasons in a typical northern Chinese city, Taiyuan. Measured personal PAH exposure levels for the urban residents in the heating and non-heating seasons were 690 (540-1051) and 404 (266-544) ng/m(3) , respectively, while, for the rural residents, they were 770 (504-1071) and 312 (201-412) ng/m(3) , respectively. Thus, rural residents are exposed to lower PAH contamination in comparison with the urban residents in the non-heating seasons. In the heating season, personal PAH inhalation exposure levels were comparable between the urban and rural residents, in part owing to the large rate of residential solid fuel consumption in the rural area for household cooking and heating. The estimated incremental lifetime cancer risks (ILCR) due to PAH exposure in Taiyuan were 3.36 × 10(-5) and 2.39 × 10(-5) for the rural and urban residents, respectively, significantly higher than the literature-reported national average level, suggesting an urgent need of PAH pollution control to protect human health. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  13. Psychological and cognitive effects of laser printer emissions: A controlled exposure study.

    Science.gov (United States)

    Herbig, B; Jörres, R A; Schierl, R; Simon, M; Langner, J; Seeger, S; Nowak, D; Karrasch, S

    2018-01-01

    The possible impact of ultrafine particles from laser printers on human health is controversially discussed although there are persons reporting substantial symptoms in relation to these emissions. A randomized, single-blinded, cross-over experimental design with two exposure conditions (high-level and low-level exposure) was conducted with 23 healthy subjects, 14 subjects with mild asthma, and 15 persons reporting symptoms associated with laser printer emissions. To separate physiological and psychological effects, a secondary physiologically based categorization of susceptibility to particle effects was used. In line with results from physiological and biochemical assessments, we found no coherent, differential, or clinically relevant effects of different exposure conditions on subjective complaints and cognitive performance in terms of attention, short-term memory, and psychomotor performance. However, results regarding the psychological characteristics of participants and their situational perception confirm differences between the participants groups: Subjects reporting symptoms associated with laser printer emissions showed a higher psychological susceptibility for adverse reactions in line with previous results on persons with multiple chemical sensitivity or idiopathic environmental intolerance. In conclusion, acute psychological and cognitive effects of laser printer emissions were small and could be attributed only to different participant groups but not to differences in exposure conditions in terms of particle number concentrations. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  14. Women's personal and indoor exposures to PM 2.5 in Mysore, India: Impact of domestic fuel usage

    Science.gov (United States)

    Andresen, Penny Rechkemmer; Ramachandran, Gurumurthy; Pai, Pramod; Maynard, Andrew

    In traditional societies, women are more likely to be adversely affected by exposures to fine particulates from domestic fuel combustion due to their role in the family as the primary cooks. In this study, 24-h gravimetric personal and indoor PM 2.5 exposures were measured for 15 women using kerosene and another 15 women using liquefied petroleum gas (LPG) as their main cooking fuel in Mysore, India. The women also answered a detailed questionnaire regarding their residential housing characteristics, health status, cooking practices and socioeconomic status. Repeated measurements were obtained during two seasons. The main objective of this study was to determine whether exposures to PM 2.5 differed according to fuel usage patterns. A repeated-measures general linear model (GLM) was used to analyze the data. Women using kerosene as their primary cooking fuel had significantly higher exposures. During summer, the arithmetic mean (± standard error) for kerosene users personal exposure was 111±13 and 71±15 μg m -3 for LPG users. Kerosene users had higher exposures in winter (177±21 μg m -3) compared to summer exposures. However, for LPG users there was no difference in their seasonal geometric mean exposures at 71±13 μg m -3. Indoor concentrations followed similar patterns. In summer, kerosene-using households had an arithmetic mean concentration of 98±9 μg m -3 and LPG-using households had an arithmetic mean concentration of 71±9 μg m -3. Winter concentrations were significantly higher than summer concentrations for kerosene users (155±13 μg m -3). Again, LPG users showed only slightly higher indoor concentrations (73±6 μg m -3) than kerosene users. Socioeconomic status, age, season and income were significant predictors of cooking fuel choice.

  15. Associations between personal exposures to VOCs and alterations in cardiovascular physiology: Detroit Exposure and Aerosol Research Study (DEARS) - presentation

    Science.gov (United States)

    Introduction: An adult cohort consisting of 63 participants engaged in the US EPA’s recent Detroit Exposure and Aerosol Research Study (DEARS) and a University of Michigan cardiovascular sub-study conducted during summer and winter periods over 3 years between 2004 and 2007...

  16. Associations between Personal Exposures to VOCs and Alterations in Cardiovascular Physiology: Detroit Exposure and Aerosol Research Study (DEARS)

    Science.gov (United States)

    Background: An adult cohort consisting of 63 participants engaged in the US EPA’s recent Detroit Exposure and Aerosol Research Study (DEARS) and a University of Michigan cardiovascular sub-study conducted during summer and winter periods over 3 years between 2004 and 2007 (5 seas...

  17. Person x Context Effects on Anticipated Moral Emotions Following Aggression

    Science.gov (United States)

    Roos, Sanna; Salmivalli, Christina; Hodges, Ernest V. E.

    2011-01-01

    We investigated person (sex, aggression level), context (witness type, victim reactions), and person x context effects on children's anticipated moral emotions following hypothetical acts of aggression against a peer. Children (N = 378, mean age = 11.3 years) were presented a series of hypothetical vignettes in which the presence of witnesses (no…

  18. Estimating the Effect of Personality on Male-Female Earnings

    NARCIS (Netherlands)

    G. Mueller; E.J.S. Plug (Erik)

    2004-01-01

    textabstractThis paper uses the Five-Factor Model of personality structure as an organizing framework to explore the effects of personality on earnings. Using data from a longitudinal survey of American high school graduates, we find that extroversion, agreeableness, conscientiousness, neuroticism

  19. Personal Finance Education: Effective Practice Guide for Schools

    Science.gov (United States)

    Spielhofer, Thomas; Kerr, David; Gardiner, Clare

    2010-01-01

    This document provides guidance on effective practice in delivering personal finance education in secondary schools. It is based on the findings from research carried out by NFER (the National Foundation for Educational Research) on behalf of pfeg (Personal Finance Education Group) as part of an evaluation of Learning Money Matters (LMM). This…

  20. The effect of person misfit on classification decisions

    NARCIS (Netherlands)

    Hendrawan, I.; Glas, Cornelis A.W.; Meijer, R.R.

    2001-01-01

    The effect of person misfit to an item response theory (IRT) model on a mastery/nonmastery decision was investigated. Also investigated was whether the classification precision can be improved by identifying misfitting respondents using person-fit statistics. A simulation study was conducted to

  1. Effectiveness of Persona with Personality Traits on Conceptual Design

    DEFF Research Database (Denmark)

    Anvari, Farshid; Richards, Deborah; Hitchens, Michael

    2015-01-01

    traits) on students’ performance in creating conceptual designs. Our results indicate that the students were able to identify the personality traits of personas and their ratings of the personalities match closely with the intended personalities. A majority of the participants stated that their designs...... were tailored to meet the needs of the given personas’ personality traits. Results suggest that the Holistic Personas can help students to take into account personality traits in the conceptual design process. Further studies are warranted to assess the value of incorporating Holistic Personas......Conceptual design is an important skill in Software Engineering. Teaching conceptual design that can deliver a useful product is challenging, particularly when access to real users is limited. This study explores the effects of the use of Holistic Personas (i.e. a persona enriched with personality...

  2. [Psychopathy and associated personality disorders: searching for a particular effect of the borderline personality disorder?].

    Science.gov (United States)

    Nioche, A; Pham, T H; Ducro, C; de Beaurepaire, C; Chudzik, L; Courtois, R; Réveillère, C

    2010-06-01

    of the testing), or a backwardness (IQantisocial personalities and scores of psychopathy (from 0.36 to 0.63); paranoid personality was less expected (from 0.32 to 0.47). Borderline personality was associated with both the total score of psychopathy (0.24) and the score of factor 2 (0.30). Linear regression analysis revealed that the antisocial and paranoid personalities predicted the total score (R(2)=38%) and the factor 2 (R(2)=45%) of the PCL-R. Antisocial and narcissistic personalities predicted factor 1 (R(2)=22%). However, in the different models, contrary as predicted, the borderline personality was not a significant predictor. First, these results underline the importance of impulsivity above all for the cluster B personality disorders and secondly, the importance of considering impulsivity with antisocial (factor 2), narcissistic and paranoid characteristics. Moreover, because of the transversality of impulsivity, the literature outlined the cross-over between cluster B disorders and psychopathy. These different studies could have important clinical consequences (risk of violence, therapeutic indications and forecast). These results also emphasize the necessity of standardised examinations. Implications for treatment are outlined: the treatment may be adapted according to the comorbidities having an effect on psychopathy that is antisocial with paranoid personalities, and antisocial with narcissistic personalities. Copyright (c) 2009 L'Encéphale, Paris. Published by Elsevier Masson SAS. All rights reserved.

  3. Problems in evaluating health effects of occupational and environmental exposures

    International Nuclear Information System (INIS)

    Gilbert, E.S.

    1981-01-01

    The assessment of health effects from low-level exposure to radiation is a matter of considerable controversy. Existing standards for exposure are based primarily on estimates of health effects obtained by extrapolation from effects of high-level exposures such as those experienced at Hiroshima and Nagasaki. Occupational and environmental exposures provide one source of data for this task. A number of studies of populations exposed in this manner have attracted recent attention. Because of the size of most of the groups and the magnitude of the exposures received, the amount that can be learned from such populations is severely limited. A number of the problems involved in analyzing and interpreting such data are addressed. Many of these problems are illustrated by a current study of the effects on mortality of occupational exposure to radiation at the Hanford plant

  4. Solar UV exposure among outdoor workers in Denmark measured with personal UV-B dosimeters: technical and practical feasibility.

    Science.gov (United States)

    Grandahl, Kasper; Mortensen, Ole Steen; Sherman, David Zim; Køster, Brian; Lund, Paul-Anker; Ibler, Kristina Sophie; Eriksen, Paul

    2017-10-10

    Exposure to solar ultraviolet radiation is a well-known cause of skin cancer. This is problematic for outdoor workers. In Denmark alone, occupational skin cancer poses a significant health and safety risk for around 400,000 outdoor workers. Objective measures of solar ultraviolet radiation exposure are needed to help resolve this problem. This can be done using personal ultraviolet radiation dosimeters. We consider technical and practical feasibility of measuring individual solar ultraviolet exposure at work and leisure in professions with different á priori temporal high-level outdoor worktime, using aluminium gallium nitride (AlGaN) photodiode detector based personal UV-B dosimeters. Essential technical specifications including the spectral and angular responsivity of the dosimeters are described and pre-campaign dosimeter calibration applicability is verified. The scale and conduct of dosimeter deployment and campaign in-field measurements including failures and shortcomings affecting overall data collection are presented. Nationwide measurements for more than three hundred and fifty workers from several different professions were collected in the summer of 2016. On average, each worker's exposure was measured for a 2-week period, which included both work and leisure. Data samples of exposure at work during a Midsummer day show differences across professions. A construction worker received high-level occupational UV exposure most of the working day, except during lunch hour, accumulating to 5.1 SED. A postal service worker was exposed intermittently around noon and in the afternoon, preceded by no exposure forenoon when packing mail, accumulating to 1.6 SED. A crane fitter was exposed only during lunch hour, accumulating to 0.7 SED. These findings are in line with our specialist knowledge as occupational physicians. Large-scale use of personal UV-B dosimeters for measurement of solar ultraviolet radiation exposure at work and leisure in Denmark is indeed

  5. Quantitative determination of circulating endothelial cells in persons with low dose radioactivity exposure

    International Nuclear Information System (INIS)

    Al-Massarani, Gh.; Najjar, F.

    2013-04-01

    The aim of this study was to determine the risk of occupational exposure to low doses of ionizing radiation on the endothelium detachment through the quantification of circulating endothelial cells (CEC) in the peripheral blood of 63 workers in the Atomic Energy Commission in Syria (AECS) using a Magnetic Immuno-separation technique (IMS) and compare the results with 28 healthy (controls) is not exposed during their careers for any type of ionizing radiation. Our study showed for the first time the significantly increasing in the circulating endothelial cells count (P <0.0001) when employees are exposed to low doses of radiation less than 50 mSv. This result with previous studies about the late effects of radiation, assuming the existence of impact late radiation exposure on the cohesion of the endothelium, despite the lack of correlation with radiation dose measured during the past four years of work in AECS (between 2006-2010). This is due to several reasons, including the small sample size and lack of commitment by some workers develop individual control films during some periods of their work. The prospective studies for such workers can allow us to know if the rise in the number of CEC will be considered an early indicator for the risk of a cardiovascular disease when workers exposed to low-doses of ionizing radiation( tens of millisievert) that up to date are considered harmless (author).

  6. Exposure of bakery and pastry apprentices to airborne flour dust using PM2.5 and PM10 personal samplers

    Directory of Open Access Journals (Sweden)

    Paris Christophe

    2007-11-01

    Full Text Available Abstract Background This study describes exposure levels of bakery and pastry apprentices to flour dust, a known risk factor of occupational asthma. Methods Questionnaires on work activity were completed by 286 students. Among them, 34 performed a series of two personal exposure measurements using a PM2.5 and PM10 personal sampler during a complete work shift, one during a cold ("winter" period, and the other during a hot ("summer" period. Results Bakery apprentices experience greater average PM2.5 and PM10 exposures than pastry apprentices (p 10 values among bakers = 1.10 mg.m-3 [standard deviation: 0.83] than in summer (0.63 mg.m-3 [0.36]. While complying with current European occupational limit values, these exposures exceed the ACGIH recommendations set to prevent sensitization to flour dust (0.5 mg.m-3. Over half the facilities had no ventilation system. Conclusion Young bakery apprentices incur substantial exposure to known airways allergens, a situation that might elicit early induction of airways inflammation.

  7. Normal mere exposure effect with impaired recognition in Alzheimer's disease

    OpenAIRE

    Willems, Sylvie; Adam, Stéphane; Van der Linden, Martial

    2002-01-01

    We investigated the mere exposure effect and the explicit memory in Alzheimer's disease (AD) patients and elderly control subjects, using unfamiliar faces. During the exposure phase, the subjects estimated the age of briefly flashed faces. The mere exposure effect was examined by presenting pairs of faces (old and new) and asking participants to select the face they liked. The participants were then presented with a forced-choice explicit recognition task. Controls subjects exhibited above-ch...

  8. Cardiovascular health effects following exposure of human volunteers during fire extinction exercises

    DEFF Research Database (Denmark)

    Andersen, Maria Helena Guerra; Saber, Anne Thoustrup; Pedersen, Peter Bøgh

    2017-01-01

    firefighting exercises in a constructed firehouse and flashover container. The subjects were instructed to extinguish fires of either wood or wood with electrical cords and mattresses. The exposure to particulate matter ( PM) was assessed at various locations and personal exposure was assessed by portable PM...... of cardiovascular effects in young conscripts training to become firefighters. Methods: Healthy conscripts (n = 43) who participated in a rescue educational course for firefighting were enrolled in the study. The exposure period consisted of a three-day training course where the conscripts participated in various...... samplers and urinary excretion of 1-hydroxypyrene. Cardiovascular measurements included microvascular function and heart rate variability (HRV). Results: The subjects were primarily exposed to PM in bystander positions, whereas self-contained breathing apparatus effectively abolished pulmonary exposure...

  9. Gamma radiation exposure of accompanying persons due to Lu-177 patients

    Directory of Open Access Journals (Sweden)

    Kovan Bilal

    2015-01-01

    Full Text Available Neuroendocrine tumours (NET are cancers usually observed and arisen in the stomach, intestine, pancreas and breathing system. Recently, radionuclide therapy applications with Lu-177 peptide compound are rapidly growing; especially effective clinical results are obtained in the treatment of well-differentiated and metastatic NET. In this treatment, Lu-177-DOTA, a beta emitter radioisotope in the radiopharmaceutical form, is given to the patient by intravenous way. Lu-177 has also gamma rays apart from beta rays. Gamma rays have 175 keV average energy and these gamma rays should be under the control in terms of radiation protection. In this study, we measured the exposure dose from the Lu-177 patient.

  10. Personal exposure to particulate matter in commuters using different transport modes (bus, bicycle, car and subway) in an assigned route in downtown Santiago, Chile.

    Science.gov (United States)

    Suárez, Liliana; Mesías, Stephanie; Iglesias, Verónica; Silva, Claudio; Cáceres, Dante D; Ruiz-Rudolph, Pablo

    2014-05-01

    The objective of this study was to compare personal exposure to particulate matter (fine and ultrafine particles) in commuters using different transport modes (bicycle, bus, car and subway) in a busy, assigned route in downtown Santiago, Chile. Volunteers carrying personal samplers completed scheduled commutes during the morning rush hours, while central site measurements were conducted in parallel. A total of 137 valid commutes were assessed. The impact of central site, traffic and other variables was explored with regression models. PM2.5 personal concentrations were equal to or slightly above central site measurements, while UFP personal concentrations were above them. Regression models showed impacts of both background levels and traffic emissions on personal PM2.5 and UFP exposure. Traffic impacts varied with transport modes. Estimates of traffic impacts on personal PM2.5 exposure were 2.0, 13.0, 16.9 and 17.5 μg m(-3), for car, bicycle, subway and bus, respectively; while for UFP exposure were 8400, 16 200, 25 600 and 30 100 counts per cm(3), for subway, car, bicycle and bus, respectively. After controlling the central site and transport mode, higher temperatures increased PM2.5 exposure and decreased UFP ones, while the wind direction affected UFP personal exposure. In conclusion, we found significant impacts of both central site background measurements and traffic emissions on personal exposure of volunteer commuters in an assigned route in Santiago, with impacts varying with transport modes.

  11. Predicting multicultural effectiveness of international students : the Multicultural Personality Questionnaire

    NARCIS (Netherlands)

    Van Oudenhoven, J.P.; Van der Zee, K.I.

    The present study considered the reliability and validity of the 78-item revised version of the Multicultural Personality Questionnaire, a multidimensional instrument aimed at measuring multicultural effectiveness of expatriate employees and students. The questionnaire includes scales for cultural

  12. Are Androgynous Individuals More Effective Persons and Parents?

    Science.gov (United States)

    Baumrind, Diana

    1982-01-01

    Using extensive, multifaceted observational and interview data from the Family Socialization and Developmental Competence Project (FSP), this paper examines the claims that androgynes, by comparison with sex-typed individuals, are more effective persons and parents. (Author/RH)

  13. The Connect Effect Building Strong Personal, Professional, and Virtual Networks

    CERN Document Server

    Dulworth, Michael

    2008-01-01

    Entrepreneur and executive development expert Mike Dulworth's THE CONNECT EFFECT provides readers with a simple framework and practical tools for developing that crucial competitive advantage: a high-quality personal, professional/organizational and virtual network.

  14. Predicting multicultural effectiveness of international students : The Multicultural Personality Questionnaire

    NARCIS (Netherlands)

    Van Oudenhoven, Jan Pieter; Van der Zee, K.I.

    2002-01-01

    The present study considered the reliability and validity of the 78-item revised version of the Multicultural Personality Questionnaire, a multidimensional instrument aimed at measuring multicultural effectiveness of expatriate employees and students. The questionnaire includes scales for cultural

  15. Effects of exposure imprecision on estimation of the benchmark dose

    DEFF Research Database (Denmark)

    Budtz-Jørgensen, Esben; Keiding, Niels; Grandjean, Philippe

    2004-01-01

    In regression analysis failure to adjust for imprecision in the exposure variable is likely to lead to underestimation of the exposure effect. However, the consequences of exposure error for determination of safe doses of toxic substances have so far not received much attention. The benchmark...... approach is one of the most widely used methods for development of exposure limits. An important advantage of this approach is that it can be applied to observational data. However, in this type of data, exposure markers are seldom measured without error. It is shown that, if the exposure error is ignored......, then the benchmark approach produces results that are biased toward higher and less protective levels. It is therefore important to take exposure measurement error into account when calculating benchmark doses. Methods that allow this adjustment are described and illustrated in data from an epidemiological study...

  16. Two languages, two personalities? Examining language effects on the expression of personality in a bilingual context.

    Science.gov (United States)

    Chen, Sylvia Xiaohua; Bond, Michael Harris

    2010-11-01

    The issue of whether personality changes as a function of language is controversial. The present research tested the cultural accommodation hypothesis by examining the impact of language use on personality as perceived by the self and by others. In Study 1, Hong Kong Chinese-English bilinguals responded to personality inventories in Chinese or English on perceived traits for themselves, typical native speakers of Chinese, and typical native speakers of English. Study 2 adopted a repeated measures design and collected data at three time points from written measures and actual conversations to examine whether bilinguals exhibited different patterns of personality, each associated with one of their two languages and the ethnicity of their interlocutors. Self-reports and behavioral observations confirmed the effects of perceived cultural norms, language priming, and interlocutor ethnicity on various personality dimensions. It is suggested that use of a second language accesses the perceived cultural norms of the group most associated with that language, especially its prototypic trait profiles, thus activating behavioral expressions of personality that are appropriate in the corresponding linguistic-social context.

  17. Effects of parent drug use and personality on toddler adjustment.

    Science.gov (United States)

    Brook, J S; Whiteman, M; Shapiro, J; Cohen, P

    1996-03-01

    The interrelation between parental drug use and parental personality and the effects on 18-month-old children's adjustment were examined. Data on the parents were available at four points in time: Time 1 at mean age 6.1 years, Time 2 at mean age 13.7 years, Time 3 at mean age 16.4 years, and at Time 4 at mean age 22.2 years. Data on their toddlers at 18 months of age were also available. Structured interviews were used to assess personality and drug use and the toddlers' adjustment. Time 3 parental personality traits were related to Time 4 personality traits, which in turn were related to toddler adjustment. The influence of parental alcohol involvement (Time 3) on toddler adjustment was mediated by parental personality (Times 3 and 4) and parental alcohol problems (Time 4). Interactive effects demonstrated that protective parental personality traits (nondrug conducive) enhanced the effects of low parental drug use, resulting in the highest amounts of toddler adjustment. There are significant pathways between parental personality and drug use and toddler adjustment. Parental protective factors enhance the effect of parental low drug use on toddler adjustment.

  18. Health effects and risks of radon exposure

    International Nuclear Information System (INIS)

    Cross, F.T.

    1990-01-01

    In view of the current widespread concern about the risks associated with indoor radon exposures, this paper explores the evidence on risk from human epidemiology studies, particularly in reference to EPA's 4-pCi/L action level value and from animal studies. While the EPA 4-pCi/L level has no legal force and is not a standard per se, it is becoming a de facto standard as several states are considering the level in pending legislation. Although risk can also be related to radiation dose from radon exposure, this perspective on risk is not treated in this chapter

  19. Mere exposure and the endowment effect on consumer decision making.

    Science.gov (United States)

    Tom, Gail; Nelson, Carolyn; Srzentic, Tamara; King, Ryan

    2007-03-01

    Previous researchers (e.g., J. A. Bargh, 1992, 2002) demonstrated the importance of nonconscious processes on consumer choice behavior. Using an advertisement, the authors determined the effect of two nonconscious processes--the mere exposure effect, which increases object preference by increasing consumer exposure to an object, and the endowment effect, which increases object valuation by providing consumer possession of an object--on consumer behavior. Although the mere exposure effect and endowment effect did not produce an interaction, they produced independent effects. The endowment effect increased object valuation but not object preference. The mere exposure effect increased object preference but not object valuation. Thus, at the unconscious level, an increase in object preference does not lead to an increase in object valuation, nor does an increase in object valuation lead to an increase in object preference. The authors discuss the importance of developing measures of unconscious process in advertising effectiveness.

  20. Obsessive Compulsive Personality Disorder as a Predictor of Exposure and Ritual Prevention Outcome for Obsessive Compulsive Disorder

    OpenAIRE

    Pinto, Anthony; Liebowitz, Michael R.; Foa, Edna B.; Simpson, H. Blair

    2011-01-01

    Despite elevated rates of obsessive compulsive personality disorder (OCPD) in patients with obsessive compulsive disorder (OCD), no study has specifically examined comorbid OCPD as a predictor of exposure and ritual prevention (EX/RP) outcome. Participants were adult outpatients (n = 49) with primary OCD and a Yale-Brown Obsessive Compulsive Scale (YBOCS) total score ≥ 16 despite a therapeutic serotonin reuptake inhibitor dose for at least 12 weeks prior to entry. Participants received 17 ses...

  1. Cardiovascular change during encoding predicts the nonconscious mere exposure effect.

    Science.gov (United States)

    Ladd, Sandra L; Toscano, William B; Cowings, Patricia S; Gabrieli, John D E

    2014-01-01

    These studies examined memory encoding to determine whether the mere exposure effect could be categorized as a form of conceptual or perceptual implicit priming and, if it was not conceptual or perceptual, whether cardiovascular psychophysiology could reveal its nature. Experiment 1 examined the effects of study phase level of processing on recognition, the mere exposure effect, and word identification implicit priming. Deep relative to shallow processing improved recognition but did not influence the mere exposure effect for nonwords or word identification implicit priming for words. Experiments 2 and 3 examined the effect of study-test changes in font and orientation, respectively, on the mere exposure effect and word identification implicit priming. Different study-test font and orientation reduced word identification implicit priming but had no influence on the mere exposure effect. Experiments 4 and 5 developed and used, respectively, a cardiovascular psychophysiological implicit priming paradigm to examine whether stimulus-specific cardiovascular reactivity at study predicted the mere exposure effect at test. Blood volume pulse change at study was significantly greater for nonwords that were later preferred than for nonwords that were not preferred at test. There was no difference in blood volume pulse change for words at study that were later either identified or not identified at test. Fluency effects, at encoding or retrieval, are an unlikely explanation for these behavioral and cardiovascular findings. The relation of blood volume pulse to affect suggests that an affective process that is not conceptual or perceptual contributes to the mere exposure effect.

  2. Using smartphones to collect time-activity data for long-term personal-level air pollution exposure assessment.

    Science.gov (United States)

    Glasgow, Mark L; Rudra, Carole B; Yoo, Eun-Hye; Demirbas, Murat; Merriman, Joel; Nayak, Pramod; Crabtree-Ide, Christina; Szpiro, Adam A; Rudra, Atri; Wactawski-Wende, Jean; Mu, Lina

    2016-06-01

    Because of the spatiotemporal variability of people and air pollutants within cities, it is important to account for a person's movements over time when estimating personal air pollution exposure. This study aimed to examine the feasibility of using smartphones to collect personal-level time-activity data. Using Skyhook Wireless's hybrid geolocation module, we developed "Apolux" (Air, Pollution, Exposure), an Android(TM) smartphone application designed to track participants' location in 5-min intervals for 3 months. From 42 participants, we compared Apolux data with contemporaneous data from two self-reported, 24-h time-activity diaries. About three-fourths of measurements were collected within 5 min of each other (mean=74.14%), and 79% of participants reporting constantly powered-on smartphones (n=38) had a daily average data collection frequency of <10 min. Apolux's degree of temporal resolution varied across manufacturers, mobile networks, and the time of day that data collection occurred. The discrepancy between diary points and corresponding Apolux data was 342.3 m (Euclidian distance) and varied across mobile networks. This study's high compliance and feasibility for data collection demonstrates the potential for integrating smartphone-based time-activity data into long-term and large-scale air pollution exposure studies.

  3. Effects of maternal dexamethasone exposure on hematological ...

    African Journals Online (AJOL)

    Exposure to dexamethasone at LD 1-14 and 1-21 significantly (P<0.05) reduced RBC and platelet counts but it raised MCV and MCH relative to control. This study suggests that prenatal and lactational dexamethasone administration may affect the hematological indices in the male offspring. Keywords: Dexamethasone ...

  4. Managing health effects of beryllium exposure

    National Research Council Canada - National Science Library

    Committee on Beryllium Alloy Exposures; Committee on Toxicology; National Research Council; Division on Earth and Life Studies; National Research Council

    2008-01-01

    ... to its occurrence in exposed people. Despite reduced workplace exposure, chronic beryllium disease continues to occur. In addition, beryllium has been classified as a likely human carcinogen by several agencies, such as the International Agency for Research on Cancer, the National Toxicology Program, and the U.S. Environmental Protection Agency. Thos...

  5. Iron decreases biological effects of ozone exposure

    Science.gov (United States)

    CONTEXT: Ozone (0(3)) exposure is associated with a disruption of iron homeostasis and increased availability of this metal which potentially contributes to an oxidative stress and biologicaleffects. OBJECTIVE: We tested the postulate that increased concentrations of iron in c...

  6. Effects of Prenatal Exposure to Phthalates

    Science.gov (United States)

    Johnson, Laurie A.

    2012-01-01

    The purpose of this review of literature is to examine the association of phthalate exposure with development. Phthalates are chemical compounds used in poly-vinyl chloride, PVC; vinyl flooring, cosmetics, shampoo, air fresheners, soft plastic items, intravenous tubing, food packaging and wraps, textiles, paints, cleaning products and detergents.…

  7. Advanced airflow distribution methods for reduction of personal exposure to indoor pollutants

    DEFF Research Database (Denmark)

    Cao, Guangyu; Kosonen, Risto; Melikov, Arsen

    2016-01-01

    The main objective of this study is to recognize possible airflow distribution methods to protect the occupants from exposure to various indoor pollutants. The fact of the increasing exposure of occupants to various indoor pollutants shows that there is an urgent need to develop advanced airflow ...... distribution methods to reduce indoor exposure to various indoor pollutants. This article presents some of the latest development of advanced airflow distribution methods to reduce indoor exposure in various types of buildings.......The main objective of this study is to recognize possible airflow distribution methods to protect the occupants from exposure to various indoor pollutants. The fact of the increasing exposure of occupants to various indoor pollutants shows that there is an urgent need to develop advanced airflow...

  8. Personality Profiles of Effective Leadership Performance in Assessment Centers.

    Science.gov (United States)

    Parr, Alissa D; Lanza, Stephanie T; Bernthal, Paul

    2016-01-01

    Most research examining the relationship between effective leadership and personality has focused on individual personality traits. However, profiles of personality traits more fully describe individuals, and these profiles may be important as they relate to leadership. This study used latent class analysis to examine how personality traits combine and interact to form subpopulations of leaders, and how these subpopulations relate to performance criteria. Using a sample of 2,461 executive-level leaders, six personality profiles were identified: Unpredictable Leaders with Low Diligence (7.3%); Conscientious, Backend Leaders (3.6%); Unpredictable Leaders (8.6%); Creative Communicators (20.8%); Power Players (32.4%); and Protocol Followers (27.1%). One profile performed well on all criteria in an assessment center; remaining profiles exhibited strengths and weaknesses across criteria. Implications and future directions for research are highlighted.

  9. High resolution spatio-temporal mapping of NO2 pollution for estimating personal exposures of the Dutch population

    Science.gov (United States)

    Soenario, Ivan; Helbich, Marco; Schmitz, Oliver; Strak, Maciek; Hoek, Gerard; Karssenberg, Derek

    2017-04-01

    Air pollution has been associated with adverse health effects (e.g., cardiovascular and respiration diseases) in the urban environments. Therefore, the assessment of people's exposure to air pollution is central in epidemiological studies. The estimation of exposures on an individual level can be done by combining location information across space and over time with spatio-temporal data on air pollution concentrations. When detailed information on peoples' space-time paths (e.g. commuting patterns calculated by means of spatial routing algorithms or tracked through GPS) and peoples' major activity locations (e.g. home location, work location) are available, it is possible to calculate more precise personal exposure levels depending on peoples' individual space-time mobility patterns. This requires air pollution values not only at a high level of spatial accuracy and high temporal granularity but such data also needs to be available on a nation-wide scale. As current data is seriously limited in this respect, we introduce a novel data set of NO2 levels across the Netherlands. The provided NO2 concentrations are accessible on hourly timestamps on a 5 meter grid cell resolution for weekdays and weekends, and each month of the year. We modeled a single Land Use Regression model using a five year average of NO2 data from the Dutch NO2 measurement network consisting of N=46 sampling locations distributed over the country. Predictor variables for this model were selected in a data-driven manner using an Elastic Net and Best Subset Selection procedure from 70 candidate predictors including traffic, industry, infrastructure and population-based variables. Subsequently, to model NO2 for each time scale (hour, week, month), the LUR coefficients were fitted using the NO2 data, aggregated per time scale. Model validation was grounded on independent data collected in an ad hoc measurement campaign. Our results show a considerable difference in urban concentrations between

  10. Gene expression profiling in persons with multiple chemical sensitivity before and after a controlled n-butanol exposure session

    DEFF Research Database (Denmark)

    Dantoft, Thomas Meinertz; Skovbjerg, Sine; Andersson, Linus

    2017-01-01

    was that unexposed and symptom-free MCS participants have similar gene expression patterns to controls and a second hypothesis that MCS participants can be separated from controls based on differential gene expression upon a controlled n-butanol exposure. Participants were exposed to 3.7 ppm n-butanol while seated...... min after being exposed to and 4 hours after the exposure. Participants suffering from MCS and healthy controls were recruited through advertisement at public places and in a local newspaper. 36 participants who considered themselves sensitive were prescreened for eligibility. 18 sensitive persons...... displayed similar gene expression levels both at baseline and after the exposure and the computed AUC values were likewise comparable between the 2 groups. The intragroup variation in expression levels among MCS participants was noticeably greater than the controls. MCS participants and controls have...

  11. Trait and state anxiety reduce the mere exposure effect

    OpenAIRE

    Sandra L Ladd; Sandra L Ladd; John D E Gabrieli; John D E Gabrieli

    2015-01-01

    The mere exposure effect refers to an affective preference elicited by exposure to previously unfamiliar items. Although it is a well-established finding, its mechanism remains uncertain, with some positing that it reflects affective processes and others positing that it reflects perceptual or motor fluency with repeated items. Here we examined whether individual differences in trait and state anxiety, which have been associated with the experience of emotion, influence the mere exposure effe...

  12. Personal medical electronic devices and walk-through metal detector security systems: assessing electromagnetic interference effects.

    Science.gov (United States)

    Guag, Joshua; Addissie, Bisrat; Witters, Donald

    2017-03-20

    There have been concerns that Electromagnetic security systems such as walk-through metal detectors (WTMDs) can potentially cause electromagnetic interference (EMI) in certain active medical devices including implantable cardiac pacemakers and implantable neurostimulators. Incidents of EMI between WTMDs and active medical devices also known as personal medical electronic devices (PMED) continue to be reported. This paper reports on emission measurements of sample WTMDs and testing of 20 PMEDs in a WTMD simulation system. Magnetic fields from sample WTMD systems were characterized for emissions and exposure of certain PMEDs. A WTMD simulator system designed and evaluated by FDA in previous studies was used to mimic the PMED exposures to the waveform from sample WTMDs. The simulation system allows for controlled PMED exposure enabling careful study with adjustable magnetic field strengths and exposure duration, and provides flexibility for PMED exposure at elevated levels in order to study EMI effects on the PMED. The PMED samples consisted of six implantable cardiac pacemakers, six implantable cardioverter defibrillators (ICD), five implantable neurostimulators, and three insulin pumps. Each PMED was exposed in the simulator to the sample WTMD waveforms using methods based on appropriate consensus test standards for each of the device type. Testing the sample PMEDs using the WTMD simulator revealed EMI effects on two implantable pacemakers and one implantable neurostimulator for exposure field strength comparable to actual WTMD field strength. The observed effects were transient and the PMEDs returned to pre-exposure operation within a few seconds after removal from the simulated WTMD exposure fields. No EMI was observed for the sample ICDs or insulin pumps. The findings are consistent with earlier studies where certain sample PMEDs exhibited EMI effects. Clinical implications were not addressed in this study. Additional studies are needed to evaluate potential PMED

  13. Creating robots with personality : the effect of personality on social intelligence

    NARCIS (Netherlands)

    Mileounis, A.; Cuijpers, R.H.; Barakova, E.I.

    2015-01-01

    This study investigates the effect of two personality traits, dominance and extroversion, on social intelligence. To test these traits, a NAO robot was used, which was teleoperated through a computer using a Wizard of Oz technique. A within-subject design was conducted with extroversion as

  14. The mere exposure effect for consumer products as a consequence of existing familiarity and controlled exposure.

    Science.gov (United States)

    Hekkert, Paul; Thurgood, Clementine; Whitfield, T W Allan

    2013-10-01

    The finding that repeated exposure to a stimulus enhances attitudes directed towards it is a well-established phenomenon. Despite this, the effects of exposure to products are difficult to determine given that they could have previously been exposed to participants any number of times. Furthermore, factors other than simple repeated exposure can influence affective evaluations for stimuli that are meaningful. In our first study, we examined the influence of existing familiarity with common objects and showed that the attractiveness of shapes representing common objects increases with their rated commonness. In our second study, we eliminated the effects of prior exposure by creating fictitious yet plausible products; thus, exposure frequency was under complete experimental control. We also manipulated the attention to be drawn to the products' designs by placing them in contexts where their visual appearance was stressed to be important versus contexts in which it was indicated that little attention had been paid to their design. Following mere exposure, attractiveness ratings increased linearly with exposure frequency, with the slope of the function being steeper for stimuli presented in an inconspicuous context-indicating that individuals engage in more deliberate processing of the stimuli when attention is drawn to their visual appearance. © 2013 Elsevier B.V. All rights reserved.

  15. Comparison of personal air benzene and urine t,t-muconic acid as a benzene exposure surrogate during turnaround maintenance in petrochemical plants.

    Science.gov (United States)

    Koh, Dong-Hee; Lee, Mi-Young; Chung, Eun-Kyo; Jang, Jae-Kil; Park, Dong-Uk

    2018-04-12

    Previous studies have shown that biomarkers of chemicals with long half-lives may be better surrogates of exposure for epidemiological analyses, leading to less attenuation of the exposure-disease association, than personal air samples. However, chemicals with short half-lives have shown inconsistent results. In the present study, we compared pairs of personal air benzene and its short-half-life urinary metabolite trans,trans-muconic acid (t,t-MA), and predicted attenuation bias of theoretical exposure-disease association. Total 669 pairs of personal air benzene and urine t,t-MA samples were taken from 474 male workers during turnaround maintenance operations held in seven petrochemical plants. Maintenance jobs were classified into 13 groups. Variance components were calculated for personal air benzene and urine t, t-MA separately to estimate the attenuation of the theoretical exposure-disease association. Personal air benzene and urine t, t-MA showed similar attenuation of the theoretical exposure-disease association. Analyses for repeated measurements showed similar results, while in analyses for values above the limits of detection (LODs), urine t, t-MA showed less attenuation of the theoretical exposure-disease association than personal air benzene. Our findings suggest that there may be no significant difference in attenuation bias when personal air benzene or urine t,t-MA is used as a surrogate for benzene exposure.

  16. Redundant correlation effect on personalized recommendation

    Science.gov (United States)

    Qiu, Tian; Han, Teng-Yue; Zhong, Li-Xin; Zhang, Zi-Ke; Chen, Guang

    2014-02-01

    The high-order redundant correlation effect is investigated for a hybrid algorithm of heat conduction and mass diffusion (HHM), through both heat conduction biased (HCB) and mass diffusion biased (MDB) correlation redundancy elimination processes. The HCB and MDB algorithms do not introduce any additional tunable parameters, but keep the simple character of the original HHM. Based on two empirical datasets, the Netflix and MovieLens, the HCB and MDB are found to show better recommendation accuracy for both the overall objects and the cold objects than the HHM algorithm. Our work suggests that properly eliminating the high-order redundant correlations can provide a simple and effective approach to accurate recommendation.

  17. Personal exposure monitoring of PM2.5 in indoor and outdoor microenvironments

    DEFF Research Database (Denmark)

    Steinle, Susanne; Reis, Stefan; Sabel, Clive E

    2015-01-01

    to define six microenvironments (MEs) to assess everyday exposure of individuals to short-term PM2.5 concentrations. The Dylos was combined with a GPS receiver to track movement and exposure of individuals across the MEs. Seventeen volunteers collected 35 profiles. Profiles may have a different overall...

  18. Personal exposure to grass pollen: relating inhaled dose to background concentration

    DEFF Research Database (Denmark)

    Peel, Robert George; Hertel, Ole; Smith, Matt

    2013-01-01

    Background: Very few studies on human exposure to allergenic pollen have been conducted using direct methods, with background concentrations measured at city center monitoring stations typically taken as a proxy for exposure despite the inhomogeneous nature of atmospheric pollen concentrations. A...

  19. Personal measures of power-frequency magnetic field exposure among men from an infertility clinic: distribution, temporal variability and correlation with their female partners' exposure

    International Nuclear Information System (INIS)

    Lewis, Ryan C.; Hauser, Russ; Maynard, Andrew D.; Neitzel, Richard L.; Meeker, John D.; Wang, Lu; Kavet, Robert; Morey, Patricia; Ford, Jennifer B.

    2016-01-01

    Power-frequency magnetic field exposure science as it relates to men and couples have not been explored despite the advantage of this information in the design and interpretation of reproductive health epidemiology studies. This analysis examined the distribution and temporal variability of exposures in men, and the correlation of exposures within couples using data from a longitudinal study of 25 men and their female partners recruited from an infertility clinic. The average and 90. percentile demonstrated fair to good reproducibility, whereas the maximum showed poor reproducibility over repeated sampling days, each separated by a median of 4.6 weeks. Average magnetic field exposures were also strongly correlated within couples, suggesting that one partner's data could be used as a surrogate in the absence of data from the other for this metric. Environment was also an important effect modifier in these explored matters. These issues should be considered in future relevant epidemiology studies. (authors)

  20. Bartonella quintana and Typhus Group Rickettsiae Exposure among Homeless Persons, Bogotá, Colombia.

    Science.gov (United States)

    Faccini-Martínez, Álvaro A; Márquez, Andrea C; Bravo-Estupiñan, Diana M; Calixto, Omar-Javier; López-Castillo, Christian A; Botero-García, Carlos A; Hidalgo, Marylin; Cuervo, Claudia

    2017-11-01

    In 2015, we investigated Bartonella quintana and typhus group rickettsiae in body lice from homeless persons in Bogotá, Colombia. We found B. quintana-infected body lice and seroprevalence of this microorganism in 19% of homeless persons and typhus group rickettsiae in 56%. Public health professionals should start preemptive measures and active vector control.

  1. Cultural differences in the primacy effect for person perception.

    Science.gov (United States)

    Noguchi, Kenji; Kamada, Akiko; Shrira, Ilan

    2014-06-01

    Previous work has shown there are robust differences in how North Americans and East Asians form impressions of people. The present research examines whether the tendency to weigh initial information more heavily-the primacy effect-may be another component of these cultural differences. Specifically, we tested whether Americans would be more likely to use first impressions to guide person perception, compared to Japanese participants. In this experiment, participants read a vignette that described a target person's behaviour, then rated the target's personality. Before reading the vignette, some trait information was given to create an expectation about the target's personality. The data revealed that Americans used this initial information to guide their judgments of the target, whereas the Japanese sample based their judgments on all the information more evenly. Thus, Americans showed a stronger primacy effect in their impression formation than Japanese participants, who engaged in more data-driven processing. © 2013 International Union of Psychological Science.

  2. Health effects of daily airborne particle dose in children: Direct association between personal dose and respiratory health effects

    International Nuclear Information System (INIS)

    Buonanno, Giorgio; Marks, Guy B.; Morawska, Lidia

    2013-01-01

    Air pollution is a widespread health problem associated with respiratory symptoms. Continuous exposure monitoring was performed to estimate alveolar and tracheobronchial dose, measured as deposited surface area, for 103 children and to evaluate the long-term effects of exposure to airborne particles through spirometry, skin prick tests and measurement of exhaled nitric oxide (eNO). The mean daily alveolar deposited surface area dose received by children was 1.35 × 10 3 mm 2 . The lowest and highest particle number concentrations were found during sleeping and eating time. A significant negative association was found between changes in pulmonary function tests and individual dose estimates. Significant differences were found for asthmatics, children with allergic rhinitis and sensitive to allergens compared to healthy subjects for eNO. Variation is a child's activity over time appeared to have a strong impact on respiratory outcomes, which indicates that personal monitoring is vital for assessing the expected health effects of exposure to particles. -- Highlights: •Particle dose was estimated through personal monitoring on more than 100 children. •We focused on real-time daily dose of particle alveolar deposited surface area. •Spirometry, skin prick and exhaled Nitric Oxide tests were performed. •Negative link was found between changes in pulmonary functions and individual doses. •A child's lifestyle appeared to have a strong impact on health respiratory outcomes. -- The respiratory health effects of daily airborne particle dose on children through personal monitoring

  3. Effects of Maternal Dexamethasone Exposure During Lactation on ...

    African Journals Online (AJOL)

    olayemitoyin

    examined the effects of lactational dexamethasone exposure on metabolic imbalance and oxidative stress marker in the liver ... control. Basal Fasting Blood Sugar (FBS) was also significantly (p<0.001) higher in the Dex ... Exposure to stress and glucocorticoids hormone ..... Energy expenditure and energy intake during.

  4. The Effects of Mere Exposure to Political Advertisements.

    Science.gov (United States)

    Becker, Lee B.; Doolittle, John C.

    Past research into the effects of "exposure" in political advertising indicates that massive "exposure" campaigns alone can show good, and sometimes dramatic, results in elections. This research is partially confirmed by a study of several mass media public relation efforts designed specifically to increase citizen recognition…

  5. Effects of high vs low-level radiation exposure

    International Nuclear Information System (INIS)

    Bond, V.P.

    1983-01-01

    In order to appreciate adequately the various possible effects of radiation, particularly from high-level vs low-level radiation exposure (HLRE, vs LLRE), it is necessary to understand the substantial differences between (a) exposure as used in exposure-incidence curves, which are always initially linear and without threshold, and (b) dose as used in dose-response curves, which always have a threshold, above which the function is curvilinear with increasing slope. The differences are discussed first in terms of generally familiar nonradiation situations involving dose vs exposure, and then specifically in terms of exposure to radiation, vs a dose of radiation. Examples are given of relevant biomedical findings illustrating that, while dose can be used with HLRE, it is inappropriate and misleading the LLRE where exposure is the conceptually correct measure of the amount of radiation involved

  6. The causal effect of paternal unemployment on children's personality

    OpenAIRE

    Angelini, Viola; Bertoni, Marco; Corazzini, Luca

    2015-01-01

    Using longitudinal data from the German Socio-Economic Panel (SOEP), we show that paternal unemployment has a surprisingly positive causal effect on the "Big 5" personality traits of children aged 17 to 25. In particular, our results from longitudinal value-added models for personality suggest that paternal unemployment makes children significantly more conscientious and less neurotic. Our results are robust to different estimation methods and to selection on unobservables. Furthermore, these...

  7. Personal monitoring of 218Po and 214Po radionuclide deposition onto individuals under normal environmental exposure conditions

    International Nuclear Information System (INIS)

    Eatough, J.P.; Worley, A.; Moss, G.R.

    1999-01-01

    Personal dosemeters have been utilized to monitor the deposition of the radon decay products 218 Po and 214 Po onto individuals under normal environmental exposure conditions. Each detector consists of TASTRAK alpha-sensitive plastic incorporated into an ordinary working wristwatch. Subsequent analysis provides energy discrimination of the detected alpha-particle decays, and allows events from the individual radon decay products 218 Po and 214 Po, attached to the detector surface, to be uniquely identified. Assuming similar deposition onto skin and detector surfaces, the activity per unit area of deposited radionuclides can be determined for exposed skin. Forty-one personal dosemeters were issued to volunteers selected through the hospital medical physics departments at Reading, Northampton, Exeter and Plymouth. Each volunteer was also issued with a personal radon dosemeter to determine their individual radon exposure. The volunteers wore the two dosemeters simultaneously and continuously for a period of around one month. Correlations were observed between the radon exposure of the individual and the activity per unit area of 218 Po and 214 Po on the detector surface. From these correlations it can be estimated that at the UK average radon exposure of 20 Bq m -3 , the number of decays/cm 2 /year on continuously exposed skin surface is between 3500 and 28 000 for 218 Po, and between 7000 and 21 000 for 214 Po. These results can be combined with theoretical modelling of the dose distribution in the skin to yield the alpha-particle radiation dose to any identified target cells. (author)

  8. Terpene exposure and respiratory effects among workers in Swedish joinery shops.

    Science.gov (United States)

    Eriksson, K A; Levin, J O; Sandström, T; Lindström-Espeling, K; Lindén, G; Stjernberg, N L

    1997-04-01

    Exposure to monoterpenes (alpha-pinene, beta-pinene and delta 3-carene) in joinery shops was studied in Sweden during the processing of Scot's pine, and the acute respiratory effects among the employees were evaluated. A cross-sectional study of 38 workers was carried out in 4 joinery shops. The investigation included personal air sampling of monoterpenes, biological monitoring of metabolites of alpha-pinene in the workers' urine, interviews following a standardized questionnaire, and dynamic spirometry. The personal exposure to monoterpenes in the joinery shops was 10-214 mg/m3. The correlation (correlation coefficient = 0.69) between exposure to alpha-pinene and verbenols (metabolites from alpha-pinene) in urine was relatively good. No acute effects on forced vital capacity or forced expiratory volume during 1 s were detected. The workers had significantly reduced preshift lung function values when compared with the values of a local reference group, even when smokers and ex-smokers were excluded. Personal exposure to the monoterpenes alpha-pinene, and delta 3-carene in joinery shops may exceed the present Swedish occupational exposure limit of 150 mg/m3 during the winter season when workroom air is commonly recirculated. The determination of metabolites of alpha-pinene (verbenols) in urine can be used as an index of exposure to fumes released during wood-treating processes. The results from the lung function tests indicate chronic rather than acute reactions in the airways. The fact that there were no major changes in lung function over a workshift indicates chronic reaction in the airways.

  9. The effect of personalized versus standard patient protocols for radiostereometric analysis (RSA).

    Science.gov (United States)

    Muharemovic, O; Troelsen, A; Thomsen, M G; Kallemose, T; Gosvig, K K

    2018-05-01

    Increasing pressure in the clinic requires a more standardized approach to radiostereometric analysis (RSA) imaging. The aim of this study was to investigate whether implementation of personalized RSA patient protocols could increase image quality and decrease examination time and the number of exposure repetitions. Forty patients undergoing primary total hip arthroplasty were equally randomized to either a case or a control group. Radiographers in the case group were assisted by personalized patient protocols containing information about each patient's post-operative RSA imaging. Radiographers in the control group used a standard RSA protocol. At three months, radiographers in the case group significantly reduced (p RSA patient protocols have a positive effect on image quality and radiation dose savings. Implementation of personal patient protocols as a RSA standard will contribute to the reduction of examination time, thus ensuring a cost benefit for department and patient safety. Copyright © 2017 The College of Radiographers. Published by Elsevier Ltd. All rights reserved.

  10. Combined Toxic Exposures and Human Health: Biomarkers of Exposure and Effect

    Directory of Open Access Journals (Sweden)

    Johan Högberg

    2011-02-01

    Full Text Available Procedures for risk assessment of chemical mixtures, combined and cumulative exposures are under development, but the scientific database needs considerable expansion. In particular, there is a lack of knowledge on how to monitor effects of complex exposures, and there are few reviews on biomonitoring complex exposures. In this review we summarize articles in which biomonitoring techniques have been developed and used. Most examples describe techniques for biomonitoring effects which may detect early changes induced by many chemical stressors and which have the potential to accelerate data gathering. Some emphasis is put on endocrine disrupters acting via epigenetic mechanisms and on carcinogens. Solid evidence shows that these groups of chemicals can interact and even produce synergistic effects. They may act during sensitive time windows and biomonitoring their effects in epidemiological studies is a challenging task.

  11. [Comparative studies of personal and steady-state sampling for determining dust exposure in different job groups].

    Science.gov (United States)

    Cherneva, P; Lukanova, R

    1994-01-01

    The variability of the dust concentration in time and space, as well as the change of worker's place during the working process, define the necessity of introducing personal sampling in the hygiene control practice. However, the laboratory equipment with personal devices is still not sufficient. The aim of this work is to assess the dust exposure of the basic professional groups from the ore- and coal production in Bulgaria by personal sampling in comparative studies of the static ambient sampling used up to now. 63 full-shift investigations of the dust factor were performed on professional groups of miners of the polymetal and coal pits by static ambient devices-[Hygitest production] and personal [from firms "Casella", "Strolein" and "Gilian"] devices, after standardized methods. The results are data processed-by means of logarithmic normal distribution of the relation of the respirable dust concentrations, determined personally and by static ambient sampling. The limits of variation of this correlation are from 0.5 to 4.1 at average geometric value -0.95 and standard geometric deviation-1.8 i.e. both types of sampling are intersubstitutional for the examined groups and sites, as in the underground ores the professional risk of respirable dust is underestimated up to 4 times at static ambient sampling.

  12. Assessment of personal exposures to optical radiation in large entertainment venues

    International Nuclear Information System (INIS)

    Bonner, R.; O'Hagan, J. B.; Khazova, M.

    2012-01-01

    Workplace exposure to optical radiation from artificial sources is regulated in Europe under the Artificial Optical Radiation Directive 2006/25/EC implemented in the UK as The Control of Artificial Optical Radiation at Work Regulations 2010. The entertainment environment often presents an extremely complex situation for the assessment of occupational exposures. Multiple illumination sources, continuously changing illumination conditions and people moving during performances add further complexity to the assessment. This document proposes a methodology for assessing the risks arising from exposure to optical radiation and presents detailed case studies of practical assessment for two large entertainment venues. (authors)

  13. Effect of sequential isoproturon pulse exposure on Scenedesmus vacuolatus.

    Science.gov (United States)

    Vallotton, Nathalie; Eggen, Rik Ilda Lambertus; Chèvre, Nathalie

    2009-04-01

    Aquatic organisms are typically exposed to fluctuating concentrations of herbicides in streams. To assess the effects on algae of repeated peak exposure to the herbicide isoproturon, we subjected the alga Scenedesmus vacuolatus to two sequential pulse exposure scenarios. Effects on growth and on the inhibition of the effective quantum yield of photosystem II (PSII) were measured. In the first scenario, algae were exposed to short, 5-h pulses at high isoproturon concentrations (400 and 1000 microg/l), each followed by a recovery period of 18 h, while the second scenario consisted of 22.5-h pulses at lower concentrations (60 and 120 microg/l), alternating with short recovery periods (1.5 h). In addition, any changes in the sensitivity of the algae to isoproturon following sequential pulses were examined by determining the growth rate-EC(50) prior to and following exposure. In both exposure scenarios, we found that algal growth and its effective quantum yield were systematically inhibited during the exposures and that these effects were reversible. Sequential pulses to isoproturon could be considered a sequence of independent events. Nevertheless, a consequence of inhibited growth during the repeated exposures is the cumulative decrease in biomass production. Furthermore, in the second scenario, when the sequence of long pulses began to approach a scenario of continuous exposure, a slight increase in the tolerance of the algae to isoproturon was observed. These findings indicated that sequential pulses do affect algae during each pulse exposure, even if algae recover between the exposures. These observations could support an improved risk assessment of fluctuating exposures to reversibly acting herbicides.

  14. Health effects of airborne exposures from concentrated animal feeding operations

    DEFF Research Database (Denmark)

    Heederik, Dick; Sigsgaard, Torben; Thorne, Peter S

    2006-01-01

    effects related to low-level gas and particulate emissions. Most information comes from studies among workers in CAFO installations. Research over the last decades has shown that microbial exposures, especially endotoxin exposure, are related to deleterious respiratory health effects, of which cross......-shift lung function decline and accelerated decline over time are the most pronounced effects. Studies in naïve subjects and workers have shown respiratory inflammatory responses related to the microbial load. This working group, which was part of the Conference on Environmental Health Impacts...... but also on potential health effects from microbial exposures, concentrating on susceptible subgroups, especially asthmatic children and the elderly, since these exposures have been shown to be related to respiratory health effects among workers in CAFOs. Udgivelsesdato: 2007-Feb...

  15. Performance of Panasonic ZP-1460 Electronic Personal Dosemeter under Exposure Conditions Likely to be Found at Fukushima Daiichi Nuclear Power Plant

    Science.gov (United States)

    Tsujimura, Norio; Yoshida, Tadayoshi; Hoshi, Katsuya; Momose, Takumaro

    A study on the performance of the Panasonic ZP-1460 electronic personal dosemeter, the model used in the aftermath of the Fukushima Daiichi nuclear power plant accident in March 2011, was conducted under actual exposure situations likely encountered in the plant. The tests pertained to (1) the dose rate response over dose rates >100 mSv/h and (2) the angular response on an anthropomorphic phantom exposed to the rotational and isotropic irradiation geometries. The test results confirmed that the dosemeter provides Hp(10) as a reasonably close estimate of the effective dose for any exposure geometries. The dosemeter response data evaluated in this study can be utilized for converting dosemeter readings to the absorbed dose to any organs and tissues for epidemiologic purposes.

  16. Effect of ultraviolet exposure on mitochondrial respiratory system

    Energy Technology Data Exchange (ETDEWEB)

    Noda, K [Kurume Univ., Fukuoka (Japan). School of Medicine

    1975-09-01

    To find the photodynamic effect of ultraviolet light on the mitochondrial respiratory chain, mitochondria were obtained from rat livers, and the suspension was exposed to an extensive ultraviolet light. The oxygen consumption was measured polarographically with a Clark oxygen electrode. The effect of ultraviolet exposure on the five states of respiratory control (Chance and Williams), the P/O ratio, and the respiratory control index in mitochondria was discussed. The ultraviolet light with a dose of 9.6 x 10/sup 6/ erg/cm/sup 2/ caused the oxidative phosphorylation in mitochondria to uncouple. The 2nd phosphorylation site of the respiratory chain was susceptible to ultraviolet exposure. The stimulation of latent ATPase activity in mitochondria following exposure was observed by increasing exposure of ultraviolet light. However, DNP-stimulated ATPase was found to be stable in activity. The uncoupling of the respiratory chain by ultraviolet exposure was not detected if the mitochondrial suspension was preincubated with bovine serum albumin before exposure. The changes in light absorption of the mitochondrial suspension were followed at 520 nm after exposure. A close correlation was found between the ultraviolet exposure and swelling in mitochondria. But, the reversing contraction was observed by adding ATP to the swelled mitochondria. The peroxide compound was formed in mitochondria irradiated with ultraviolet light. The amount of compounds formed was dependent on the radiant energy of ultraviolet light. The possible mechanisms involved in the photodynamic effect of ultraviolet light to the mitochondrial respiration system were discussed.

  17. Hypothalamic pituitary thyroid axis and exposure to interpersonal violence in childhood among women with borderline personality disorder

    Directory of Open Access Journals (Sweden)

    Cave Sinai

    2014-05-01

    Full Text Available Background: A relationship between exposure to sexual violence and thyroid hormone alterations has been observed among women with posttraumatic stress disorder (PTSD. Women with borderline personality disorder (BPD report a high estimate of childhood trauma. Objective: The aim of the present study was to assess relationships between thyroid hormone measures and exposure to violence in childhood in women with BPD. Method: A total of 92 clinically euthyroid women with BPD (53% with comorbid PTSD diagnosis and at least two prior suicide attempts were assessed with the Karolinska Interpersonal Violence Scales (KIVS. The KIVS contains four subscales with concrete examples of exposure to violence and expressed violent behavior in childhood (aged 6–14 years and during adult life (15 years or older. Baseline thyroid function was evaluated by measuring plasma free and bound triiodothyronine (FT3 and T3, thyroxine (FT4 and T4, and thyroid-stimulating hormone (TSH with immunoassays. The FT3/FT4 ratio was used to estimate peripheral deiodination. Plasma cortisol was also assessed. Results: Sixty-seven percent of patients reported medium high or high level of exposure to interpersonal violence as a child. The FT3/FT4 ratio showed a significant negative correlation with exposure to violence as a child. Patients with PTSD had significantly higher plasma cortisol levels. An ad hoc analysis revealed that the correlation between KIVS exposure to interpersonal violence as a child and FT3/FT4 ratio was significant only in patients with comorbid PTSD. Altered thyroid activity, especially FT3/FT4, levels was associated with exposure to violence in childhood in women with BPD. Conclusion: Severe childhood trauma-related stress may promote lasting altered thyroid levels and/or contribute to the development of psychopathology associated with BPD traits or PTSD.

  18. Predicting adult pulmonary ventilation volume and wearing complianceby on-board accelerometry during personal level exposure assessments

    Science.gov (United States)

    Rodes, C. E.; Chillrud, S. N.; Haskell, W. L.; Intille, S. S.; Albinali, F.; Rosenberger, M. E.

    2012-09-01

    BackgroundMetabolic functions typically increase with human activity, but optimal methods to characterize activity levels for real-time predictions of ventilation volume (l min-1) during exposure assessments have not been available. Could tiny, triaxial accelerometers be incorporated into personal level monitors to define periods of acceptable wearing compliance, and allow the exposures (μg m-3) to be extended to potential doses in μg min-1 kg-1 of body weight? ObjectivesIn a pilot effort, we tested: 1) whether appropriately-processed accelerometer data could be utilized to predict compliance and in linear regressions to predict ventilation volumes in real-time as an on-board component of personal level exposure sensor systems, and 2) whether locating the exposure monitors on the chest in the breathing zone, provided comparable accelerometric data to other locations more typically utilized (waist, thigh, wrist, etc.). MethodsPrototype exposure monitors from RTI International and Columbia University were worn on the chest by a pilot cohort of adults while conducting an array of scripted activities (all volumes in-situ. For the subset of participants with complete data (n = 22), linear regressions were constructed (processed accelerometric variable versus ventilation rate) for each participant and exposure monitor type, and Pearson correlations computed to compare across scenarios. ResultsTriaxial accelerometer data were demonstrated to be adequately sensitive indicators for predicting exposure monitor wearing compliance. Strong linear correlations (R values from 0.77 to 0.99) were observed for all participants for both exposure sensor accelerometer variables against ventilation volume for recumbent, sedentary, and ambulatory activities with MET values ˜volume data. Computing accelerometric standard deviations allowed good sensitivity for compliance assessments even for sedentary activities. These pilot findings supported the hypothesis that a common linear

  19. Affect labeling enhances exposure effectiveness for public speaking anxiety.

    Science.gov (United States)

    Niles, Andrea N; Craske, Michelle G; Lieberman, Matthew D; Hur, Christopher

    2015-05-01

    Exposure is an effective treatment for anxiety but many patients do not respond fully. Affect labeling (labeling emotional experience) attenuates emotional responding. The current project examined whether affect labeling enhances exposure effectiveness in participants with public speaking anxiety. Participants were randomized to exposure with or without affect labeling. Physiological arousal and self-reported fear were assessed before and after exposure and compared between groups. Consistent with hypotheses, participants assigned to Affect Labeling, especially those who used more labels during exposure, showed greater reduction in physiological activation than Control participants. No effect was found for self-report measures. Also, greater emotion regulation deficits at baseline predicted more benefit in physiological arousal from exposure combined with affect labeling than exposure alone. The current research provides evidence that behavioral strategies that target prefrontal-amygdala circuitry can improve treatment effectiveness for anxiety and these effects are particularly pronounced for patients with the greatest deficits in emotion regulation. Copyright © 2015 Elsevier Ltd. All rights reserved.

  20. Stimulus Threat and Exposure Context Modulate the Effect of Mere Exposure on Approach Behaviors.

    Science.gov (United States)

    Young, Steven G; Jones, Isaiah F; Claypool, Heather M

    2016-01-01

    Mere-exposure (ME) research has found that initially neutral objects made familiar are preferred relative to novel objects. Recent work extends these preference judgments into the behavioral domain by illustrating that mere exposure prompts approach-oriented behavior toward familiar stimuli. However, no investigations have examined the effect of mere exposure on approach-oriented behavior toward threatening stimuli. The current work examines this issue and also explores how exposure context interacts with stimulus threat to influence behavioral tendencies. In two experiments participants were presented with both mere-exposed and novel stimuli and approach speed was assessed. In the first experiment, when stimulus threat was presented in a homogeneous format (i.e., participants viewed exclusively neutral or threatening stimuli), ME potentiated approach behaviors for both neutral and threatening stimuli. However, in the second experiment, in which stimulus threat was presented in a heterogeneous fashion (i.e., participants viewed both neutral and threatening stimuli), mere exposure facilitated approach only for initially neutral stimuli. These results suggest that ME effects on approach behaviors are highly context sensitive and depend on both stimulus valence and exposure context. Further implications of these findings for the ME literature are discussed.

  1. Personal exposures to NO2 in the EXPOLIS-study: relation to residential indoor, outdoor and workplace concentrations in Basel, Helsinki and Prague

    International Nuclear Information System (INIS)

    Kousa, A.; Rotko, T.; Alm, S.; Monn, C.

    2001-01-01

    Personal exposures, residential indoor, outdoor and workplace levels of nitrogen dioxide (NO 2 ) were measured for 262 urban adult (25-55 years) participants in three EXPOLIS centres (Basel, Switzerland; Helsinki, Finland; and Prague, Czech Republic) using passive samplers for 48-h sampling periods during 1996-1997. The average residential outdoor and indoor NO 2 levels were lowest in Helsinki (24 ± 12 and 18 ± 11 μgm -3 , respectively), highest in Prague (61 ± 20 and 43 ± 23μgm -3 ), with Basel in between (36 ± 13 and 27± 13μgm -3 ). Average workplace NO 2 levels, however, were highest in Basel (36 ± 24μgm -3 ), lowest in Helsinki (27 ± 15μgm -3 ), with Prague in between (30 ± 18μgm -3 ). A time-weighted microenvironmental exposure model explained 74% of the personal exposure variation in all centre and in average 88% of the exposures. Log-linear regression models, using residential outdoor measurements (fixed site monitoring) combined with residential and work characteristics (i.e. work location, using gas appliances and keeping windows open), explained 48% (37%) of the personal NO 2 exposure variation. Regression models based on ambient fixed site concentrations alone explained only 11-19% of personal NO 2 exposure variation. Thus, ambient fixed site monitoring alone was a poor predictor for personal NO 2 exposure variation, but adding personal questionnaire information can significantly improve the predicting power. (Author)

  2. Characterization of the personal dosimeter Rn-disk for monitoring radon exposure

    International Nuclear Information System (INIS)

    Orlando, P.; Arcovito, G.; Amici, M.; Orlando, C.; Cardellini, F.; Fiorentino, A.; Trevisi, R.

    2009-01-01

    Rn-disk is a new passive device for measuring occupational exposure to radon 222, are presented the results of tests for the characterization of the dosimeter as a tool for estimating the individual dose for workers. [it

  3. Distribution of Exhaled Contaminants and Personal Exposure in a Room using Three Different Air Distribution Strategies

    DEFF Research Database (Denmark)

    Olmedo, Inés; Nielsen, Peter V.; Adana, M. Ruiz de

    2012-01-01

    The level of exposure to human exhaled contaminants in a room depends not only on the air distribution system but also on people’s different positions, the distance between them, people’s activity level and height, direction of exhalation, and the surrounding temperature and temperature gradient...... between the manikins are changed to study the influence on the level of exposure. The results show that the air exhaled by a manikin flows a longer distance with a higher concentration in case of displacement ventilation than in the other two cases, indicating a significant exposure to the contaminants....... Human exhalation is studied in detail for different distribution systems: displacement and mixing ventilation as well as a system without mechanical ventilation. Two thermal manikins breathing through the mouth are used to simulate the exposure to human exhaled contaminants. The position and distance...

  4. Effectiveness of hepatitis A vaccination as post-exposure prophylaxis

    Science.gov (United States)

    Parrón, Ignasi; Planas, Caritat; Manzanares-Laya, Sandra; Martínez, Ana; Sala, Maria Rosa; Minguell, Sofia; Jané, Mireia

    2017-01-01

    ABSTRACT Hepatitis A (HA) has been a vaccine-preventable disease since 1995. In Catalonia, a universal combined hepatitis A+B vaccination program of preadolescents was initiated at the end of 1998. However, outbreaks are reported each year and post-exposure prophylaxis (PEP) with hepatitis A virus (HAV) vaccine or immunoglobulin (IG) is recommended to avoid cases. The aim of this study was to assess the effectiveness of HAV vaccine and IG in preventing hepatitis A cases in susceptible exposed people. A retrospective cohort study of contacts of HA cases involved in outbreaks reported in Catalonia between January 2006 and December 2012 was made. The rate ratios and 95% confidence intervals (CI) of HA in susceptible contacts receiving HAV or IG versus those without PEP were calculated. There were 3550 exposed persons in the outbreaks studied: 2381 received one dose of HAV vaccine (Hepatitis A or hepatitis A+B), 190 received IG, and 611 received no PEP. 368 exposed subjects received one dose of HAV vaccine and IG simultaneously and were excluded from the study. The effectiveness of PEP was 97.6% (95% CI 96.2–98.6) for HAV vaccine and 98.3% (95% CI 91.3–99.9) for IG; the differences were not statistically significant (p = 0.36). The elevated effectiveness of HAV vaccination for PEP in HA outbreaks, similar to that of IG, and the long-term protection of active immunization, supports the preferential use of vaccination to avoid secondary cases. PMID:27925847

  5. Personal coping strategies for managing the side effects of ...

    African Journals Online (AJOL)

    This study describes the burden of side effects from ARV treatment as experienced by a sample of HIV/AIDS patients and identifies the personal strategies they used to cope with ... The most common adverse effects reported were tiredness, nightmares, mood swings, nausea, poor appetite, insomnia, vomiting and dizziness.

  6. The effect of adventure-based experiential learning on personal ...

    African Journals Online (AJOL)

    The purpose of the study was to determine the effectiveness of Adventure-based Experiential Learning (AEL) in developing the personal effectiveness of adolescents. Twenty three adolescents, currently enrolled in a post-matriculation development centre were studied. The study consisted of an experimental (n=12) and ...

  7. The Effect of Personalization on Smartphone-Based Fall Detectors

    Directory of Open Access Journals (Sweden)

    Carlos Medrano

    2016-01-01

    Full Text Available The risk of falling is high among different groups of people, such as older people, individuals with Parkinson's disease or patients in neuro-rehabilitation units. Developing robust fall detectors is important for acting promptly in case of a fall. Therefore, in this study we propose to personalize smartphone-based detectors to boost their performance as compared to a non-personalized system. Four algorithms were investigated using a public dataset: three novelty detection algorithms—Nearest Neighbor (NN, Local Outlier Factor (LOF and One-Class Support Vector Machine (OneClass-SVM—and a traditional supervised algorithm, Support Vector Machine (SVM. The effect of personalization was studied for each subject by considering two different training conditions: data coming only from that subject or data coming from the remaining subjects. The area under the receiver operating characteristic curve (AUC was selected as the primary figure of merit. The results show that there is a general trend towards the increase in performance by personalizing the detector, but the effect depends on the individual being considered. A personalized NN can reach the performance of a non-personalized SVM (average AUC of 0.9861 and 0.9795, respectively, which is remarkable since NN only uses activities of daily living for training.

  8. Characteristics and personal exposures of carbonyl compounds in the subway stations and in-subway trains of Shanghai, China.

    Science.gov (United States)

    Feng, Yanli; Mu, Cuicui; Zhai, Jinqing; Li, Jian; Zou, Ting

    2010-11-15

    Carbonyl compounds including their concentrations, potential sources, diurnal variations and personal exposure were investigated in six subway stations and in-subway trains in Shanghai in June 2008. The carbonyls were collected onto solid sorbent (Tenax TA) coated with pentafluorophenyl hydrazine (PFPH), followed by solvent extraction and gas chromatography (GC)/mass spectrometry (MS) analysis of the PFPH derivatives. The total carbonyl concentrations of in-subway train were about 1.4-2.5 times lower than in-subway stations. A significant correlation (R>0.5, psubway stations. The diurnal variations in both the subway station and in-subway train showed that the concentrations of most carbonyls were much higher in the morning rush hour than in other sampling periods. Additionally, pronounced diurnal variations of acetaldehyde concentration before and after the evening peak hour in the subway train suggested that passengers contributed to high acetaldehyde levels. The personal exposure showed that the underground subway stations were important microenvironment for exposure to formaldehyde and acetaldehyde. Copyright © 2010 Elsevier B.V. All rights reserved.

  9. Personal Care Products Are Only One of Many Exposure Routes of Natural Toxic Substances to Humans and the Environment

    Directory of Open Access Journals (Sweden)

    Thomas D. Bucheli

    2018-01-01

    Full Text Available The special issue “A Critical View on Natural Substances in Personal Care Products” is dedicated to addressing the multidisciplinary special challenges of natural ingredients in personal care products (PCP and addresses also environmental exposure. In this perspective article, we argue that environmental exposure is probably not so much dominated by PCP use, but in many cases by direct emission from natural or anthropogenically managed vegetation, including agriculture. In support of this hypothesis, we provide examples of environmental fate and behaviour studies for compound classes that are either listed in the International Nomenclature of Cosmetics Ingredients (INCI or have been discussed in a wider context of PCP applications and have been classified as potentially harmful to humans and the environment. Specifically, these include estrogenic isoflavones, the carcinogenic ptaquiloside and pyrrolizidine alkaloids, saponins, terpenes and terpenoids, such as artemisinin, and mycotoxins. Research gaps and challenges in the domains of human and environmental exposure assessment of natural products common to our currently rather separated research communities are highlighted.

  10. How Do Stress Exposure and Stress Regulation Relate to Borderline Personality Disorder?

    OpenAIRE

    Bourvis, Nadège; Aouidad, Aveline; Cabelguen, Clémence; Cohen, David; Xavier, Jean

    2017-01-01

    Borderline personality disorder (BPD) is a severe and frequent disorder characterized by a pervasive pattern of instability affecting impulse control, emotional regulation, cognitive processing, self-image and interpersonal relationships. Patients’ personal histories are often marked by stressful or traumatic experiences, either unique or repeated. Moreover, while clinical signs of the disorder include both chronic and acute features, acute features are mostly triggered by acute stressful sit...

  11. The Role of Personality and Subjective Exposure Experiences in Posttraumatic Stress Disorder and Depression Symptoms among Children Following Wenchuan Earthquake.

    Science.gov (United States)

    Chen, Xiacan; Xu, Jiajun; Li, Bin; Li, Na; Guo, Wanjun; Ran, Mao-Sheng; Zhang, Jun; Yang, Yanchun; Hu, Junmei

    2017-12-08

    This study aims to investigate the role of personality traits and subjective exposure experiences in posttraumatic stress disorder and depression symptoms. In Qingchuan, 21,652 children aged 7 to 15 years were assessed using face-to-face interviews one year after the Wenchuan earthquake in China. The Junior Eysenck Personality Questionnaire, a modified earthquake exposure scale, the UCLA Posttraumatic Stress Disorder Reaction Index (adolescent), and the Adolescent Depression Inventory were used to assess personality characteristics, trauma experiences, posttraumatic stress disorder and depression symptoms, respectively. The measurement was completed with 20,749 children. After adjusting for other factors by multinomial logistic regression analysis, neuroticism, having felt unable to escape from the disaster and having been trapped for a longer time were risk factors of posttraumatic stress disorder and depression symptoms. Socialization was a protective factor of them. Having felt extreme panic or fear was a risk factor of posttraumatic stress disorder symptoms. For depression symptoms, introversion and psychoticism were risk factors, and extraversion was a protective factor. This study was conducted with the largest representative sample of child survivors of a natural, devastating disaster in a developing country. These results could be useful for planning psychological intervention strategies for children and for influencing further research.

  12. The Exposure Advantage: Early Exposure to a Multilingual Environment Promotes Effective Communication.

    Science.gov (United States)

    Fan, Samantha P; Liberman, Zoe; Keysar, Boaz; Kinzler, Katherine D

    2015-07-01

    Early language exposure is essential to developing a formal language system, but may not be sufficient for communicating effectively. To understand a speaker's intention, one must take the speaker's perspective. Multilingual exposure may promote effective communication by enhancing perspective taking. We tested children on a task that required perspective taking to interpret a speaker's intended meaning. Monolingual children failed to interpret the speaker's meaning dramatically more often than both bilingual children and children who were exposed to a multilingual environment but were not bilingual themselves. Children who were merely exposed to a second language performed as well as bilingual children, despite having lower executive-function scores. Thus, the communicative advantages demonstrated by the bilinguals may be social in origin, and not due to enhanced executive control. For millennia, multilingual exposure has been the norm. Our study shows that such an environment may facilitate the development of perspective-taking tools that are critical for effective communication. © The Author(s) 2015.

  13. Is it really not possible to use electronic personal dosimeters in clinical exposure situations?

    International Nuclear Information System (INIS)

    Borowski, M.; Poppe, B.; Looe, H.K.; Boetticher, H. von

    2010-01-01

    Purpose: Due to significant measuring inaccuracies that can occur under certain conditions, the use of electronic personal dosimeters in statutory measurements in X-ray diagnostics is currently legally restricted. The present study investigates the clinically relevant situations in which measurement errors of more then 20 % can be anticipated. Materials and Methods: Four series of experiments were made, comparing the results of the electronic personal dosimeter EPD Mk2.3 to those of reference dosimeters (TLDs and diagnostic dosimeters). On the one hand, personal doses have been determined in the routine operation of controlled areas in various departments. On the other hand, measurements on phantoms have been conducted in extreme but realistic situations under radiation protection. Experiments were conducted in unweakened scattered radiation as well as in unattenuated and attenuated direct radiation. Results: The tested electronic personal dosimeter type meets the requirements regarding measurement accuracy for 'official' personal dosimeters in all of the examined clinically relevant scattered radiation fields. Only if exposed to radiation directly, an underestimation of the dose can occur and can be greater than 90 %. Conclusion: In the range of scattered radiation of diagnostic X-ray equipment, even in pulsed fields, the use of electronic personal dosimeters is reasonable. Considerable measurement errors can only arise in radiation fields that are not realistic under regular conditions and even in connection with most accidents. (orig.)

  14. Effects of zinc exposure on the accumulation, haematology and ...

    African Journals Online (AJOL)

    Effects of zinc exposure on the accumulation, haematology and immunology of Mozambique tilapia, Oreochromis mossambicus. Ekrem Şanver Çelik, Hasan Kaya, Sevdan Yilmaz, Mehmet Akbulut, Arınç Tulgar ...

  15. Human Health Effects Associated with Exposure to Toxic Cyanobacteria

    Science.gov (United States)

    Reports of toxic cyanobacteria blooms are increasing worldwide. Warming and eutrophic surface water systems support the development of blooms. We examine the evidence for adverse human health effects associated with exposure to toxic blooms in drinking water, recreational water a...

  16. Radiation effects after low dose chronic long-term exposure

    International Nuclear Information System (INIS)

    Fliedner, T.M.; Friesecke, I.

    1997-01-01

    This document approaches the radiation effects after low dose chronic long-term exposure, presenting examples occurred, the pathophysiologic mechanisms for cell system tolerance in elevated radiation fields, and the diagnostic and therapeutic possibilities

  17. Particulate matter 2.5 (PM2.5) personal exposure evaluation on mechanics and administrative officers at the motor vehicle testing center at Pulo Gadung, DKI Jakarta.

    Science.gov (United States)

    Rizky, Zuly Prima; Yolla, Patricia Bebby; Ramdhan, Doni Hikmat

    2016-03-01

    Exposure to fine particulate matter (PM2.5) in both the short and long term has been known to cause deaths and health effects, especially related to the heart, blood vessels, and lungs. Based on this information, researchers conducted this study at a motor vehicle testing center unit at Pulo Gadung, in Jarkarta, to determine the concentration of PM2.5 that workers were exposed to. The major source of PM2.5 in this area is from the exhaust of gas emissions from motor vehicles, which is one of the largest contributors to the levels of PM in urban areas. Ten mechanics were picked from 16 mechanics that work in this station. Four administration workers from different posts were also picked to participate. The researcher conducted the PM2.5 personal exposure measurement during weekdays from 6 to 14 April 2015 (2 workers/day). This research was conducted to measure the particle number concentration with size Organization Air Quality Guidelines, the PM2.5 exposure of the mechanics and administrative officers exceeded the recommended exposure (25 μm/m3).

  18. The effect of personality on daily life emotional processes.

    Science.gov (United States)

    Komulainen, Emma; Meskanen, Katarina; Lipsanen, Jari; Lahti, Jari Marko; Jylhä, Pekka; Melartin, Tarja; Wichers, Marieke; Isometsä, Erkki; Ekelund, Jesper

    2014-01-01

    Personality features are associated with individual differences in daily emotional life, such as negative and positive affectivity, affect variability and affect reactivity. The existing literature is somewhat mixed and inconclusive about the nature of these associations. The aim of this study was to shed light on what personality features represent in daily life by investigating the effect of the Five Factor traits on different daily emotional processes using an ecologically valid method. The Experience Sampling Method was used to collect repeated reports of daily affect and experiences from 104 healthy university students during one week of their normal lives. Personality traits of the Five Factor model were assessed using NEO Five Factor Inventory. Hierarchical linear modeling was used to analyze the effect of the personality traits on daily emotional processes. Neuroticism predicted higher negative and lower positive affect, higher affect variability, more negative subjective evaluations of daily incidents, and higher reactivity to stressors. Conscientiousness, by contrast, predicted lower average level, variability, and reactivity of negative affect. Agreeableness was associated with higher positive and lower negative affect, lower variability of sadness, and more positive subjective evaluations of daily incidents. Extraversion predicted higher positive affect and more positive subjective evaluations of daily activities. Openness had no effect on average level of affect, but predicted higher reactivity to daily stressors. The results show that the personality features independently predict different aspects of daily emotional processes. Neuroticism was associated with all of the processes. Identifying these processes can help us to better understand individual differences in daily emotional life.

  19. Pupil response and the subliminal mere exposure effect.

    Science.gov (United States)

    Yoshimoto, Sanae; Imai, Hisato; Kashino, Makio; Takeuchi, Tatsuto

    2014-01-01

    The subliminal mere exposure effect (SMEE) is the phenomenon wherein people tend to prefer patterns they have repeatedly observed without consciously identifying them. One popular explanation for the SMEE is that perceptual fluency within exposed patterns is misattributed to a feeling of preference for those patterns. Assuming that perceptual fluency is negatively correlated with the amount of mental effort needed to analyze perceptual aspects of incoming stimuli, pupil diameter should associate with SMEE strength since the former is known to reflect mental effort. To examine this hypothesis, we measured participants' pupil diameter during exposure to subthreshold stimuli. Following exposure, a preference test was administered. Average pupil diameter throughout exposure was smaller when the SMEE was induced than when the SMEE was not induced. This supports the hypothesis that increasing perceptual fluency during mere exposure modulates autonomic nervous responses, such as pupil diameter, and eventually leads to preference.

  20. Pupil Response and the Subliminal Mere Exposure Effect

    Science.gov (United States)

    Yoshimoto, Sanae; Imai, Hisato; Kashino, Makio; Takeuchi, Tatsuto

    2014-01-01

    The subliminal mere exposure effect (SMEE) is the phenomenon wherein people tend to prefer patterns they have repeatedly observed without consciously identifying them. One popular explanation for the SMEE is that perceptual fluency within exposed patterns is misattributed to a feeling of preference for those patterns. Assuming that perceptual fluency is negatively correlated with the amount of mental effort needed to analyze perceptual aspects of incoming stimuli, pupil diameter should associate with SMEE strength since the former is known to reflect mental effort. To examine this hypothesis, we measured participants’ pupil diameter during exposure to subthreshold stimuli. Following exposure, a preference test was administered. Average pupil diameter throughout exposure was smaller when the SMEE was induced than when the SMEE was not induced. This supports the hypothesis that increasing perceptual fluency during mere exposure modulates autonomic nervous responses, such as pupil diameter, and eventually leads to preference. PMID:24587408

  1. Pupil response and the subliminal mere exposure effect.

    Directory of Open Access Journals (Sweden)

    Sanae Yoshimoto

    Full Text Available The subliminal mere exposure effect (SMEE is the phenomenon wherein people tend to prefer patterns they have repeatedly observed without consciously identifying them. One popular explanation for the SMEE is that perceptual fluency within exposed patterns is misattributed to a feeling of preference for those patterns. Assuming that perceptual fluency is negatively correlated with the amount of mental effort needed to analyze perceptual aspects of incoming stimuli, pupil diameter should associate with SMEE strength since the former is known to reflect mental effort. To examine this hypothesis, we measured participants' pupil diameter during exposure to subthreshold stimuli. Following exposure, a preference test was administered. Average pupil diameter throughout exposure was smaller when the SMEE was induced than when the SMEE was not induced. This supports the hypothesis that increasing perceptual fluency during mere exposure modulates autonomic nervous responses, such as pupil diameter, and eventually leads to preference.

  2. Televised antismoking advertising: effects of level and duration of exposure.

    Science.gov (United States)

    Dunlop, Sally; Cotter, Trish; Perez, Donna; Wakefield, Melanie

    2013-08-01

    We assessed the effects of levels and duration of exposure to televised antismoking advertising on cognitive and behavioral changes. We used data from a serial cross-sectional telephone survey with weekly interviews of adult smokers and recent quitters in New South Wales, Australia (n = 13,301), between April 2005 and December 2010. We merged survey data with commercial TV ratings data to estimate individuals' exposure to antismoking advertising. Logistic regression analyses indicated that after adjustment for a wide range of potential confounders, exposure to antismoking advertising at levels between 100 and 200 gross rating points per week on average over 6 to 9 weeks was associated with an increased likelihood of having (1) salient quitting thoughts and (2) recent quit attempts. Associations between exposure for shorter periods and these outcomes were not significant. Broadcasting schedules may affect the success of antismoking ads. Campaign planners should ensure advertising exposure at adequate frequency over relatively sustained periods to maximize impact.

  3. Effects of Ambient Air Pollution Exposure on Olfaction: A Review.

    Science.gov (United States)

    Ajmani, Gaurav S; Suh, Helen H; Pinto, Jayant M

    2016-11-01

    Olfactory dysfunction affects millions of people worldwide. This sensory impairment is associated with neurodegenerative disease and significantly decreased quality of life. Exposure to airborne pollutants has been implicated in olfactory decline, likely due to the anatomic susceptibility of the olfactory nerve to the environment. Historically, studies have focused on occupational exposures, but more recent studies have considered effects from exposure to ambient air pollutants. To examine all relevant human data evaluating a link between ambient pollution exposure and olfaction and to review supporting animal data in order to examine potential mechanisms for pollution-associated olfactory loss. We identified and reviewed relevant articles from 1950 to 2015 using PubMed and Web of Science and focusing on human epidemiologic and pathophysiologic studies. Animal studies were included only to support pertinent data on humans. We reviewed findings from these studies evaluating a relationship between environmental pollutant exposure and olfactory function. We identified and reviewed 17 articles, with 1 additional article added from a bibliography search, for a total of 18 human studies. There is evidence in human epidemiologic and pathologic studies that increased exposure to ambient air pollutants is associated with olfactory dysfunction. However, most studies have used proxies for pollution exposure in small samples of convenience. Human pathologic studies, with supporting animal work, have also shown that air pollution can contact the olfactory epithelium, translocate to the olfactory bulb, and migrate to the olfactory cortex. Pollutants can deposit at each location, causing direct damage and disruption of tissue morphology or inducing local inflammation and cellular stress responses. Ambient air pollution may impact human olfactory function. Additional studies are needed to examine air pollution-related olfactory impacts on the general population using measured

  4. Scented traces--Dermal exposure of synthetic musk fragrances in personal care products and environmental input assessment.

    Science.gov (United States)

    Homem, Vera; Silva, Eduardo; Alves, Arminda; Santos, Lúcia

    2015-11-01

    Synthetic musks are organic compounds used as fragrance and fixative additives in several personal care products. Until now, little is known about their occurrence and distribution in these household commodities. However, this information is essential to perform a human dermal exposure assessment. Therefore, this study gives an overview on the levels of 12 synthetic musks in 140 personal care products from 7 different categories (body and hair wash, toilet soaps, shaving products, dentifrice products, deodorants/antiperspirants, moisturizers and perfumes). They were analysed by QuEChERS extraction followed by gas chromatography-mass spectrometry. Detection limits were found between 0.01ngg(-1) (galaxolide) and 5.00ngg(-1) (musk xylene). Higher average concentrations of total synthetic musks were detected in perfumes (5245.05μgg(-1)) and shampoos (487.67μgg(-1)) for adults. Galaxolide, exaltolide and cashmeran were the most detected compounds. Combining these results with the daily usage amounts, an average daily dermal exposure of 75.69μgkgbw(-1)day(-1) for adults and 15.54μgkgbw(-1)day(-1) for babies/children was achieved. The main contributors for adult and babies/children dermal exposure were perfumes and lotions, respectively. About 40% of the adult daily dermal exposure is related to exaltolide, 30% galaxolide, and 15% tonalide, while for babies/children 96% occurs due to exaltolide. An estimate of the amount of musks discharged "down-the-drain" into the wastewater treatment systems through the use of toiletries was also performed. An average emission per capita of 6.7mgday(-1) was determined and galaxolide and exaltolide were the predominant musks in the effluents. Copyright © 2015 Elsevier Ltd. All rights reserved.

  5. Trait and state anxiety reduce the mere exposure effect

    Directory of Open Access Journals (Sweden)

    Sandra L Ladd

    2015-05-01

    Full Text Available The mere exposure effect refers to an affective preference elicited by exposure to previously unfamiliar items. Although it is a well-established finding, its mechanism remains uncertain, with some positing that it reflects affective processes and others positing that it reflects perceptual or motor fluency with repeated items. Here we examined whether individual differences in trait and state anxiety, which have been associated with the experience of emotion, influence the mere exposure effect. Participants’ trait (Study 1 and state (Study 2 anxiety were characterized with the State-Trait Anxiety Inventory. Greater trait and state anxiety correlated with greater negative affect and lesser positive affect. In both experiments, greater anxiety was associated with a reduced mere exposure effect. Measures of fluency (response times at study and test were unrelated to the mere exposure effect. These findings support the role of affective processes in the mere exposure effect, and offer a new insight into the nature of anxiety such that anxiety is associated with a reduced experience of positive affect typically associated with familiarity.

  6. Neurophysiological evidence that perceptions of fluency produce mere exposure effects.

    Science.gov (United States)

    Leynes, P Andrew; Addante, Richard J

    2016-08-01

    Recent exposure to people or objects increases liking ratings, the "mere exposure effect" (Zajonc in American Psychologist, 35, 117-123, 1968), and an increase in processing fluency has been identified as a potential mechanism for producing this effect. This fluency hypothesis was directly tested by altering the trial-by-trial image clarity (i.e., fluency) while Event-Related Potentials (ERPs) were recorded. In Experiment 1, clarity was altered across two trial blocks that each had homogenous trial-by-trial clarity, whereas clarity varied randomly across trials in Experiment 2. Blocking or randomizing image clarity across trials was expected to produce different levels of relative fluency and alter mere exposure effects. The mere exposure effect (i.e., old products liked more than new products) was observed when stimulus clarity remained constant across trials, and clear image ERPs were more positive than blurry image ERPs. Importantly, these patterns were reversed when clarity varied randomly across test trials, such that participants liked clear images more than blurry (i.e., no mere exposure effect) and clear image ERPs were more negative than blurry image ERPs. The findings provide direct experimental support from both behavioral and electrophysiological measures that, in some contexts, mere exposure is the product of top-down interpretations of fluency.

  7. Trait and state anxiety reduce the mere exposure effect.

    Science.gov (United States)

    Ladd, Sandra L; Gabrieli, John D E

    2015-01-01

    The mere exposure effect refers to an affective preference elicited by exposure to previously unfamiliar items. Although it is a well-established finding, its mechanism remains uncertain, with some positing that it reflects affective processes and others positing that it reflects perceptual or motor fluency with repeated items. Here we examined whether individual differences in trait and state anxiety, which have been associated with the experience of emotion, influence the mere exposure effect. Participants' trait (Study 1) and state (Study 2) anxiety were characterized with the State-Trait Anxiety Inventory. Greater trait and state anxiety correlated with greater negative affect and lesser positive affect. In both experiments, greater anxiety was associated with a reduced mere exposure effect. Measures of fluency (response times at study and test) were unrelated to the mere exposure effect. These findings support the role of affective processes in the mere exposure effect, and offer a new insight into the nature of anxiety such that anxiety is associated with a reduced experience of positive affect typically associated with familiarity.

  8. The Los Angeles TEAM Study: personal exposures, indoor-outdoor air concentrations, and breath concentrations of 25 volatile organic compounds.

    Science.gov (United States)

    Wallace, L; Nelson, W; Ziegenfus, R; Pellizzari, E; Michael, L; Whitmore, R; Zelon, H; Hartwell, T; Perritt, R; Westerdahl, D

    1991-04-01

    The U.S. Environmental Protection Agency and the California Air Resources Board studied the exposures of 51 residents of Los Angeles, California, to 25 volatile organic chemicals (VOCs) in air and drinking water in 1987. A major goal of the study was to measure personal, indoor, and outdoor air concentrations, and breath concentrations of VOCs in persons living in households that had previously been measured in 1984. Other goals were to confirm the marked day-night and seasonal differences observed in 1984; to determine room-to-room variability within homes; to determine source emission rates by measuring air exchange rates in each home; and to extend the coverage of chemicals by employing additional sampling and analysis methods. A total of 51 homes were visited in February of 1987, and 43 of these were revisited in July of 1987. The results confirmed previous TEAM Study findings of higher personal and indoor air concentrations than outdoor concentrations of all prevalent chemicals (except carbon tetrachloride); higher personal, indoor, and outdoor air concentrations in winter than in summer; and (in winter only) higher outdoor concentrations at night than in the daytime. New findings included the following: (1) room-to-room variability of 12-hour average concentrations was very small, indicating that a single monitor may be adequate for estimating indoor concentrations over this time span; (2) "whole-house" source emission rates were relatively constant during both seasons, with higher rates for odorous chemicals such as p-dichlorobenzene and limonene (often used in room air fresheners) than for other classes of chemicals; (3) breath concentrations measured during morning and evening were similar for most participants, suggesting the suitability of breath measurements for estimating exposure in the home; (4) limited data obtained on two additional chemicals-toluene and methylene chloride-indicated that both were prevalent at fairly high concentrations and that

  9. EFFECTS OF TRITIUM GAS EXPOSURE ON EPDM ELASTOMER

    Energy Technology Data Exchange (ETDEWEB)

    Clark, E.

    2009-12-11

    Samples of four formulations of ethylene-propylene diene monomer (EPDM) elastomer were exposed to initially pure tritium gas at one atmosphere and ambient temperature for various times up to about 420 days in closed containers. Two formulations were carbon-black-filled commercial formulations, and two were the equivalent formulations without filler synthesized for this work. Tritium effects on the samples were characterized by measuring the sample volume, mass, flexibility, and dynamic mechanical properties and by noting changes in appearance. The glass transition temperature was determined by analysis of the dynamic mechanical properties. The glass transition temperature increased significantly with tritium exposure, and the unfilled formulations ceased to behave as elastomers after the longest tritium exposure. The filled formulations were more resistant to tritium exposure. Tritium exposure made all samples significantly stiffer and therefore much less able to form a reliable seal when employed as O-rings. No consistent change of volume or density was observed; there was a systematic lowering of sample mass with tritium exposure. In addition, the significant radiolytic production of gas, mainly protium (H{sub 2}) and HT, by the samples when exposed to tritium was characterized by measuring total pressure in the container at the end of each exposure and by mass spectroscopy of a gas sample at the end of each exposure. The total pressure in the containers more than doubled after {approx}420 days tritium exposure.

  10. The ripple effect: personal scholarships and impact on practice development

    Directory of Open Access Journals (Sweden)

    Lesley Baillie

    2015-05-01

    Full Text Available Background: Practice development projects are often situated within a specific context and team, while scholarship awards focus more on the personal and professional development of individuals. Personal and professional development is an important component of practice development, however, and this paper reports on a survey of nurses and midwives who had been awarded personal scholarships and examines the scholars’ perceptions of the impact on practice development. Few studies of scholarships and their impact have been published previously. Aims: 1. To present the outcomes of a research project that evaluated scholarships awarded to nurses and midwives, within the context of practice development 2. To critique the role of personal scholarships as a means to support practice development and/ or service improvement Methods: An online cross-sectional survey of nurses and midwives who had been awarded scholarships by a UK charity was conducted; 82 scholars responded, a 59% response rate. Quantitative data were analysed using descriptive statistics and free text comments were analysed thematically. Results: Scholars overwhelmingly perceived a positive impact on their personal and professional development but most also believed there had been a positive impact on patient care, safety and experience, and on colleagues and their organisation; some referred to the latter as a ‘ripple’ effect of their scholarship. An analysis of these results indicated some synergy with practice development values. Conclusions: The award of scholarships to individuals appears to have a wider impact on scholars’ colleagues and their organisation with a resulting impact on practice development. This is important as few individuals are awarded personal scholarships. The explicit promotion of personal scholarships within a practice development framework could further develop the relationship between the two, affirming a wider impact of the awards. The sustainability

  11. Examining the effects of birth order on personality.

    Science.gov (United States)

    Rohrer, Julia M; Egloff, Boris; Schmukle, Stefan C

    2015-11-17

    This study examined the long-standing question of whether a person's position among siblings has a lasting impact on that person's life course. Empirical research on the relation between birth order and intelligence has convincingly documented that performances on psychometric intelligence tests decline slightly from firstborns to later-borns. By contrast, the search for birth-order effects on personality has not yet resulted in conclusive findings. We used data from three large national panels from the United States (n = 5,240), Great Britain (n = 4,489), and Germany (n = 10,457) to resolve this open research question. This database allowed us to identify even very small effects of birth order on personality with sufficiently high statistical power and to investigate whether effects emerge across different samples. We furthermore used two different analytical strategies by comparing siblings with different birth-order positions (i) within the same family (within-family design) and (ii) between different families (between-family design). In our analyses, we confirmed the expected birth-order effect on intelligence. We also observed a significant decline of a 10th of a SD in self-reported intellect with increasing birth-order position, and this effect persisted after controlling for objectively measured intelligence. Most important, however, we consistently found no birth-order effects on extraversion, emotional stability, agreeableness, conscientiousness, or imagination. On the basis of the high statistical power and the consistent results across samples and analytical designs, we must conclude that birth order does not have a lasting effect on broad personality traits outside of the intellectual domain.

  12. Low-dose effects hypothesis and observations on NPP personal

    Energy Technology Data Exchange (ETDEWEB)

    Georgieva, R.; Acheva, A.; Boteva, R.; Chobanova, N.; Djounova, J.; Gyuleva, I.; Ivanova, K.; Kurchatova, G.; Milchev, A.; Negoicheva, K.; Nikolov, V.; Panova, D.; Pejankov, I.; Rupova, I.; Stankova, K.; Zacharieva, E. [Radiobiology Department, National Centre of Radiobiology and Radiation Protection, Sofia (Bulgaria)

    2013-07-01

    In the modern world the use of various sources of ionizing radiation is nearly ubiquitous. They have numerous applications in industry, medicine, science, agriculture, etc. Radiation doses to workers nevertheless are commensurable to the natural background exposure. Published data on the health effects of occupational radiation exposure are often contradictory. Addressing the issue of „negative” (bystander effects, genomic instability) and „positive” (adaptive response, radiation hormesis) effects of low doses is important and has a significant social and economic impact. In this paper we summarize the results of our extensive monitoring of nuclear power plant (NPP) staff. We believe it is a cohort suitable for analysis of health effects at low doses, because of their good medical and dosimetric control. Our results rather support the idea of absence of adverse health effects in NPP workers. (author)

  13. Biomarkers of nanomaterial exposure and effect: current status

    Science.gov (United States)

    Iavicoli, Ivo; Leso, Veruscka; Manno, Maurizio; Schulte, Paul A.

    2014-03-01

    Recent advances in nanotechnology have induced a widespread production and application of nanomaterials. As a consequence, an increasing number of workers are expected to undergo exposure to these xenobiotics, while the possible hazards to their health remain not being completely understood. In this context, biological monitoring may play a key role not only to identify potential hazards from and to evaluate occupational exposure to nanomaterials, but also to detect their early biological effects to better assess and manage risks of exposure in respect of the health of workers. Therefore, the aim of this review is to provide a critical evaluation of potential biomarkers of nanomaterial exposure and effect investigated in human and animal studies. Concerning exposure biomarkers, internal dose of metallic or metal oxide nanoparticle exposure may be assessed measuring the elemental metallic content in blood or urine or other biological materials, whereas specific molecules may be carefully evaluated in target tissues as possible biomarkers of biologically effective dose. Oxidative stress biomarkers, such as 8-hydroxy-deoxy-guanosine, genotoxicity biomarkers, and inflammatory response indicators may also be useful, although not specific, as biomarkers of nanomaterial early adverse health effects. Finally, potential biomarkers from "omic" technologies appear to be quite innovative and greatly relevant, although mechanistic, ethical, and practical issues should all be resolved before their routine application in occupational settings could be implemented. Although all these findings are interesting, they point out the need for further research to identify and possibly validate sensitive and specific biomarkers of exposure and effect, suitable for future use in occupational biomonitoring programs. A valuable contribution may derive from the studies investigating the biological behavior of nanomaterials and the factors influencing their toxicokinetics and reactivity. In

  14. Balancing speech intelligibility versus sound exposure in selection of personal hearing protection equipment for Chinook aircrews

    NARCIS (Netherlands)

    Wijngaarden, S.J. van; Rots, G.

    2001-01-01

    Background: Aircrews are often exposed to high ambient sound levels, especially in military aviation. Since long-term exposure to such noise may cause hearing damage, selection of adequate hearing protective devices is crucial. Such devices also affect speech intelligibility. When speech

  15. Bill proposition related to the protection of persons against exposure to radon in dwellings - Nr 4390

    International Nuclear Information System (INIS)

    Dord, Dominique; Colombier, Georges; Forissier, Nicolas; Luca, Lionnel; Carayon, Bernard; Blanc, Etienne; Remiller, Jacques; Perrut, Bernard; Voisin, Michel; Diard, Eric; Poletti, Berengere; Fort, Marie-Louise; Ciotti, Eric; Guibal, Jean-Claude; Gest, Alain; Roccaserra, Camille de; Delatte, Remi

    2012-01-01

    After having recalled the extent of the risk associated with exposure to radon in France, and that a regulation already exists for professional premises and buildings receiving public, this document contains the measures proposed to define a regulatory framework for dwellings. It addresses radon concentration values, radon volume activity thresholds, radon diagnosis practices, actors, protocols and reports

  16. Control of exposure to exhaled air from sick occupant with wearable personal exhaust unit

    DEFF Research Database (Denmark)

    Bolashikov, Zhecho Dimitrov; Melikov, Arsen Krikor; Barova, Maria I.

    2014-01-01

    of the doctor at three different distances. It was operated at 0.25 or 0.50 L/s under mixing background ventilation at 3 ACH. The use of wearable personal exhaust resulted in cleaner air in the room compared to mixing alone at 12 ACH. The high potential to capture exhaled air makes the device efficient against...

  17. Effect of chronic 85Kr exposure

    International Nuclear Information System (INIS)

    Willard, D.H.; DeFord, H.S.; Ballou, J.E.

    1980-01-01

    Groups of rats exposed continuously for 15 mo to 85 Kr atmospheres have received measured dose rates of 2750, 370, and 38 rad/yr. With more than 75% of the rats still alive, there has been no dose-related effect on weight gain but a probably significant effect on survival

  18. The exposure to and health effects of antimony

    DEFF Research Database (Denmark)

    Cooper, Ross G.; Harrison, Adrian Paul

    2009-01-01

    . Antimony toxicity is dependent on the exposure dose, duration, route (breathing, eating, drinking, or skin contact), other chemical exposures, age, sex, nutritional status, family traits, life style, and state of health. Chronic exposure to antimony in the air at levels of 9 mg/m3 may exacerbate irritation...... of the eyes, skin, and lungs. Long-term inhalation of antimony can potentiate pneumoconiosis, altered electrocardiograms, stomach pain, diarrhea, vomiting, and stomach ulcers, results which were confirmed in laboratory animals. Although there were investigations of the effect of antimony in sudden infant...

  19. The mediating effect of depression between exposure to potentially traumatic events and PTSD in news journalists

    Directory of Open Access Journals (Sweden)

    Klas Backholm

    2012-08-01

    Full Text Available Background: News journalists are an occupational group with a unique task at the scene of an unfolding crisis—to collect information and inform the public about the event. By being on location, journalists put themselves at risk for being exposed to the potentially traumatic event. Objective: To compare potentially traumatic exposure during work assignments at a crisis scene and in personal life as predictors of the development of post-traumatic stress disorder (PTSD in news journalists. Further, to investigate the mediating effect of depression between the predictor and predicted variables. Method: With a web-based questionnaire, information from a sample of Finnish news journalists (n=407 was collected. The data collected included details on the range of potentially traumatic assignments (PTAs at the crisis scene during the past 12 months, lifetime potentially traumatic events (PTEs in personal life, PTSD symptoms, and level of depression. Results: Approximately 50% of the participants had worked with a PTA during the past 12 months. Depression had a significant indirect effect on the relationship between PTAs at the scene and symptoms of PTSD. A similar result was found regarding the relationship between personal life PTEs and PTSD. Depression had a complete indirect effect in the case of PTAs and a partial indirect effect in regard to PTE exposure in personal life. Conclusions: Exposure to PTAs is common within journalistic work. The results reflect the importance of understanding the underlying mechanisms of the measured symptoms (PTSD, depression in relation to trauma history. The main limitations of the study include the cross-sectional design and the nature of the instruments used for the collection of work-related trauma history.

  20. Personal Coaching: Reflection on a Model for Effective Learning

    Science.gov (United States)

    Griffiths, Kerryn

    2015-01-01

    The article "Personal Coaching: A Model for Effective Learning" (Griffiths, 2006) appeared in the "Journal of Learning Design" Volume 1, Issue 2 in 2006. Almost ten years on, Kerryn Griffiths reflects upon her original article. Specifically, Griffiths looks back at the combined coaching-learning model she suggested in her…

  1. Effect of person centered counselling on depressive symptoms ...

    African Journals Online (AJOL)

    Effect of person centered counselling on depressive symptoms among Type II diabetic patients attending the general ... The clinic visits in both groups were repeated at weeks 2, 4, 6, 8, 10 and 12 making a total of six sessions for both groups.

  2. Effects of Perceived Causality on Perceptions of Persons Who Stutter

    Science.gov (United States)

    Boyle, Michael P.; Blood, Gordon W.; Blood, Ingrid M.

    2009-01-01

    This study examined the effects of the perceived cause of stuttering on perceptions of persons who stutter (PWS) using a 7-item social distance scale, a 25-item adjective pair scale and a 2-item visual analogue scale. Two hundred and four university students rated vignettes which varied on describing a PWS with different causalities for stuttering…

  3. Group Leader Development: Effects of Personal Growth and Psychoeducational Groups

    Science.gov (United States)

    Ohrt, Jonathan H.; Robinson, E. H., III; Hagedorn, W. Bryce

    2013-01-01

    The purpose of this quasi-experimental study was to compare the effects of personal growth groups and psychoeducational groups on counselor education students' (n = 74) empathy and group leader self-efficacy. Additionally, we compared the degree to which participants in each group valued: (a) cohesion, (b) catharsis, and (c) insight. There were no…

  4. Personality as a moderator of context effects on academic achievement

    NARCIS (Netherlands)

    Hendriks, A.A.J.; Kuyper, H.; Lubbers, M.J; Van der Werf, M.P.C.

    We investigated whether personality moderates group influence of classmates on academic achievement and whether these so-called context effects can be attributed to peer pressure. The sample consisted of 2498 students in their first year of Dutch secondary education. The data were analyzed by a

  5. Personality as a Moderator of Context Effects on Academic Achievement

    Science.gov (United States)

    Hendriks, A. A. Jolijn; Kuyper, Hans; Lubbers, Miranda J.; Van der Werf, Margaretha P. C.

    2011-01-01

    We investigated whether personality moderates group influence of classmates on academic achievement and whether these so-called context effects can be attributed to peer pressure. The sample consisted of 2498 students in their first year of Dutch secondary education. The data were analyzed by a two-level (students within classes) analysis,…

  6. Personality Characteristics of Counselors Rated as Effective or Ineffective.

    Science.gov (United States)

    Wiggins, J. D.; Weslander, D. L.

    1979-01-01

    Vocational Preference Inventory (VPI) was used to discriminate counselors rated as highly effective, as average, or as ineffective. Results indicated significant correlations between tested personality characteristics and rated job performances. Employment level, sex, age, certification, and degree status were of no significance in predicting…

  7. Personalized dementia care: proven effectiveness of psychosocial interventions in subgroups

    NARCIS (Netherlands)

    van Mierlo, L.D.; van der Roest, H.G.; Meiland, F.J.M.; Dröes, R.M.

    2010-01-01

    Many psychosocial intervention studies report effects in subgroups of people with dementia. Insight into the characteristics of these subgroups is important for care practice. This study reviews personal characteristics of people with dementia (living in the community or in an institution) that are

  8. The effects of substance misuse on the personality traits of ...

    African Journals Online (AJOL)

    The present study examined the effects of substance misuse on the personality traits of impulsivity and risky sexual decision-making. One hundred and one participants (101) were recruited via opportunist sampling, which comprise of 49 female, 52 male, 5 homosexual, 2 bisexual and 92 heterosexual with the mean age of ...

  9. Assessing Instructional Modalities: Individualized Treatment Effects for Personalized Learning

    Science.gov (United States)

    Beemer, Joshua; Spoon, Kelly; Fan, Juanjuan; Stronach, Jeanne; Frazee, James P.; Bohonak, Andrew J.; Levine, Richard A.

    2018-01-01

    Estimating the efficacy of different instructional modalities, techniques, and interventions is challenging because teaching style covaries with instructor, and the typical student only takes a course once. We introduce the individualized treatment effect (ITE) from analyses of personalized medicine as a means to quantify individual student…

  10. Effects of repeated skin exposure to low nickel concentrations

    DEFF Research Database (Denmark)

    Nielsen, N H; Menné, T; Kristiansen, J

    1999-01-01

    and nickel allergy, either on normal or on SLS-treated forearm skin. The present study strongly suggests that the changes observed were specific to nickel exposure. Standardized methods to assess trace to moderate nickel exposure on the hands, and the associated effects in nickel-sensitized subjects......We studied the effects of repeated daily exposure to low nickel concentrations on the hands of patients with hand eczema and nickel allergy. The concentrations used were chosen to represent the range of trace to moderate occupational nickel exposure. The study was double-blinded and placebo...... controlled. Patients immersed a finger for 10 min daily into a 10-p.p.m. nickel concentration in water for the first week, and during the second week into a 100-p.p.m. nickel concentration. This regimen significantly increased (P = 0.05) local vesicle formation and blood flow (P = 0.03) as compared...

  11. Effect of uranium chronic exposure on the moult in crayfish

    International Nuclear Information System (INIS)

    Simon, O.; Camilleri, V.; Garnier-Laplace, J.

    2004-01-01

    Throughout any ecological risk assessment, one can try to establish a link between pollutant in the ecosystem and adverse biological effects. A number of methodological approaches are based on the development of the use of bio-markers such as the enzyme activity measurements (biotransformation enzymes, antioxidant enzymes) and/or bioaccumulation markers (metal in target-organs). These data allow obtaining an early-warning signal of exposure and potential involved effects and help risk management. However, the effects at higher hierarchical levels (organism or population) are not frequently considered because they tend to occur after longer exposure periods. On the basis of previous results obtained to quantify uranium biokinetics in the crayfish Orconectes limosus and to understand the influence of the exposure pathway, a chronic exposure experiment was performed for 100 days at an environmentally relevant uranium concentration in water (low level concentration ranging from?? to 100 nM). The main effect studied was focused on the moult; moulted animals being the most sensitive to pollutants. Effects on the moult process were assessed in terms of occurrence, delay, and success. Preliminary results that indicated no induction of the moult by U exposure and better survival rate to uranium exposure must be confirmed. Simultaneously, both enzymatic bio-markers of effect quantifying the oxidative status (catalase, superoxide dismutase and glutathione peroxidases) and markers of exposure (uranium distribution at organs and cellular levels and MET observations) were studied. Results obtained from complementary experiments on the uranium fluxes all over moult states were used to discuss the link between bio-markers responses and observed effects on the moult. (author)

  12. Effect of uranium chronic exposure on the moult in crayfish

    Energy Technology Data Exchange (ETDEWEB)

    Simon, O.; Camilleri, V.; Garnier-Laplace, J. [CEA Cadarache (DEI/SECRE/LRE), Laboratory of Radioecology and Ecotoxicology, Institute for Radioprotection and Nuclear Safety, 13 - Saint-Paul-lez-Durance (France)

    2004-07-01

    Throughout any ecological risk assessment, one can try to establish a link between pollutant in the ecosystem and adverse biological effects. A number of methodological approaches are based on the development of the use of bio-markers such as the enzyme activity measurements (biotransformation enzymes, antioxidant enzymes) and/or bioaccumulation markers (metal in target-organs). These data allow obtaining an early-warning signal of exposure and potential involved effects and help risk management. However, the effects at higher hierarchical levels (organism or population) are not frequently considered because they tend to occur after longer exposure periods. On the basis of previous results obtained to quantify uranium biokinetics in the crayfish Orconectes limosus and to understand the influence of the exposure pathway, a chronic exposure experiment was performed for 100 days at an environmentally relevant uranium concentration in water (low level concentration ranging from?? to 100 nM). The main effect studied was focused on the moult; moulted animals being the most sensitive to pollutants. Effects on the moult process were assessed in terms of occurrence, delay, and success. Preliminary results that indicated no induction of the moult by U exposure and better survival rate to uranium exposure must be confirmed. Simultaneously, both enzymatic bio-markers of effect quantifying the oxidative status (catalase, superoxide dismutase and glutathione peroxidases) and markers of exposure (uranium distribution at organs and cellular levels and MET observations) were studied. Results obtained from complementary experiments on the uranium fluxes all over moult states were used to discuss the link between bio-markers responses and observed effects on the moult. (author)

  13. Residential exposure to radiofrequency fields from mobile phone base stations, and broadcast transmitters: a population-based survey with personal meter

    OpenAIRE

    VIEL, JF; CLERC, S; BARRERA, C; RYMZHANOVA, R; MOISSONNIER, M; HOURS, M; CARDIS, E

    2009-01-01

    Objectives: Both the public perceptions, and most published epidemiologic studies, rely on the assumption that the distance of a particular residence from a base station or a broadcast transmitter is an appropriate surrogate for exposure to radiofrequency fields, although complex propagation characteristics affect the beams from antennas. The main goal of this study was to characterise the distribution of residential exposure from antennas using personal exposure meters.Results: Much of the t...

  14. Risk exposures for human ornithosis in a poultry processing plant modified by use of personal protective equipment: an analytical outbreak study.

    Science.gov (United States)

    Williams, C J; Sillis, M; Fearne, V; Pezzoli, L; Beasley, G; Bracebridge, S; Reacher, M; Nair, P

    2013-09-01

    Ornithosis outbreaks in poultry processing plants are well-described, but evidence for preventive measures is currently lacking. This study describes a case-control study into an outbreak of ornithosis at a poultry processing plant in the East of England, identified following three employees being admitted to hospital. Workers at the affected plant were recruited via their employer, with exposures assessed using a self-completed questionnaire. Cases were ascertained using serological methods or direct antigen detection in sputum. 63/225 (28%) staff participated, with 10% of participants showing evidence of recent infection. Exposure to the killing/defeathering and automated evisceration areas, and contact with viscera or blood were the main risk factors for infection. Personal protective equipment (goggles and FFP3 masks) reduced the effect of exposure to risk areas and to self-contamination with potentially infectious material. Our study provides some evidence of effectiveness for respiratory protective equipment in poultry processing plants where there is a known and current risk of ornithosis. Further studies are required to confirm this tentative finding, but in the meantime respiratory protective equipment is recommended as a precautionary measure in plants where outbreaks of ornithosis occur.

  15. Health Effects Related to Wind Turbine Noise Exposure

    DEFF Research Database (Denmark)

    Schmidt, Jesper Hvass; Klokker, Mads

    2014-01-01

    BACKGROUND: Wind turbine noise exposure and suspected health-related effects thereof have attracted substantial attention. Various symptoms such as sleep-related problems, headache, tinnitus and vertigo have been described by subjects suspected of having been exposed to wind turbine noise...... existing statistically-significant evidence indicating any association between wind turbine noise exposure and tinnitus, hearing loss, vertigo or headache. LIMITATIONS: Selection bias and information bias of differing magnitudes were found to be present in all current studies investigating wind turbine...

  16. No effect of mobile phone-like RF exposure on patients with atopic dermatitis.

    Science.gov (United States)

    Johansson, Amanda; Forsgren, Sture; Stenberg, Berndt; Wilén, Jonna; Kalezic, Nebojsa; Sandström, Monica

    2008-07-01

    This study investigates the effect of exposure to a mobile phone-like radiofrequency (RF) electromagnetic field on people with atopic dermatitis (AD). Fifteen subjects with AD were recruited and matched with 15 controls without AD. The subjects were exposed for 30 min to an RF field at 1 W/kg via an indoor base station antenna attached to a 900 MHz GSM mobile phone. Blood samples for ELISA analysis of the concentration of substance P (SP), tumor necrosis factor receptor 1 (TNF R1), and brain derived neurotrophic factor (BDNF) in serum were drawn before and after the provocation (exposure/sham). Baseline heart rate and heart rate variability, local blood flow, and electrodermal activity were also recorded. No significant differences between the subject groups were found for baseline neurophysiological data. The cases displayed a serum concentration of TNF R1 significantly higher than the control subjects and a significantly lower serum concentration of BDNF in the baseline condition. For SP there was no difference between groups. However, no effects related to RF exposure condition were encountered for any of the measured substances. As to symptoms, a possible correlation with exposure could not be evaluated, due to too few symptom reports. The result of the study does not support the hypothesis of an effect of mobile phone-like RF exposure on serum levels of SP, TNF R1, and BDNF in persons with AD.

  17. The effects of exposure to environmental factors on Heart Rate Variability: An ecological perspective

    International Nuclear Information System (INIS)

    Schnell, Izhak; Potchter, Oded; Epstein, Yoram; Yaakov, Yaron; Hermesh, Hagai; Brenner, Shmuel; Tirosh, Emanuel

    2013-01-01

    The impact of human exposure to environmental factors on Heart Rate Variability (HRV) was examined in the urban space of Tel-Aviv-Jaffa. Four environmental factors were investigated: thermal and social loads; CO concentrations and noise. Levels of HRV are explained mainly by subjective social stresses, noise and CO. The most interesting result is the fact that while subjective social stress and noise increase HRV, low levels of CO are reducing HRV to some extent moderating the impact of subjective social stress and noise. Beyond the poisoning effect of CO and the fact that extremely low levels of HRV associated with high dozes of CO increase risk for life, low levels of CO may have a narcotic effect, as it is measured by HRV. The effects of thermal loads on HRV are negligible probably due to the use of behavioral means in order to neutralize heat and cold effects. -- Highlights: ► The impact of human exposure to environmental factors on Heart Rate Variability (HRV) was examined. ► Previous studies measured human exposure to pollution by fixed monitoring stations. ► This study measured actual personal exposure by mini sensors. ► High level of subjective social load and noise increase HRV. ► Low levels of CO may have a narcotic effect, as it is measured by HRV. -- The research focuses on the effects of environmental factors; noise, subjective social stress, thermal load and CO on Heart Rate Variability

  18. Effects upon health of occupational exposure to microwave radiation (radar)

    International Nuclear Information System (INIS)

    Robinette, C.D.; Silverman, C.; Jablon, S.

    1980-01-01

    The effects of occupational experience with microwave radiation (radar) on the health of US enlisted Naval personnel were studied in cohorts of approximately 20,000 men with maximum opportunity for exposure (electronic equipment repair) and 20,000 with minimum potential for exposure (equipment operation) who served during the Korean War period. Potential exposure was assessed in terms of occupational duties, length of time in occupation and power of equipment at the time of exposure. Actual exposure to members of each cohort could not be established. Mortality by cause of death, hospitalization during military service, later hospitalization in Veterans Administration (VA) facilities, and VA disability compensation were the health indexes studied, largely through the use of automated record systems. No adverse effects were detected in these indexes that could be attributed to potential microwave radiation exposures during the period 1950-1954. Functional and behavioral changes and ill-defined conditions, such as have been reported as microwave effects, could not be investigated in this study but subgroups of the living study population can be identified for expanded follow-up

  19. The system of personal monitoring and the evaluation of occupational exposure to external ionizing radiation in Cuba

    International Nuclear Information System (INIS)

    Molina, Daniel; Castro, Ailza; Martinez, Ernesto; Pernas, Rene

    2008-01-01

    Full text: Personal monitoring of workers is recommended or required by the International Basic Safety Standards for Protection against Ionizing Radiation and for the Safety of Radiation Sources. In our country the personal monitoring of external exposure to ionizing radiation is carried out by External Dosimetry Laboratory (LDE) of the Center for Radiation Protection and Hygiene (CPHR). We have implemented an individual monitoring service based on thermoluminescence dosimetry system. The service includes whole body and extremity dosimeters. We have two systems; one is base on a manual Toledo TLD reader and the other on an automatic RADOS TLD system. This service is recognized by the National Regulatory Authority in the field of radiation protection and safety. We have implemented a quality assurance (QA) programme designed according to the recommendations of the ISO/IEC 17025 standards. The papers deals with the presentation of these QA programme which includes administrative data and information, technical checking of the equipment, acceptance tests of new dosimeters and equipment, issuing and processing of the dosimeters, dose evaluation, record keeping and reporting, traceability, handling of complaints, internal reviews and external audits. The papers also describe the results of occupational exposure for the different practices during 2006-2007 period. (author)

  20. Effectiveness of Case Management for Homeless Persons: A Systematic Review

    Science.gov (United States)

    de Vet, Renée; van Luijtelaar, Maurice J. A.; Brilleslijper-Kater, Sonja N.; Vanderplasschen, Wouter; Beijersbergen, Mariëlle D.

    2013-01-01

    We reviewed the literature on standard case management (SCM), intensive case management (ICM), assertive community treatment (ACT), and critical time intervention (CTI) for homeless adults. We searched databases for peer-reviewed English articles published from 1985 to 2011 and found 21 randomized controlled trials or quasi-experimental studies comparing case management to other services. We found little evidence for the effectiveness of ICM. SCM improved housing stability, reduced substance use, and removed employment barriers for substance users. ACT improved housing stability and was cost-effective for mentally ill and dually diagnosed persons. CTI showed promise for housing, psychopathology, and substance use and was cost-effective for mentally ill perso