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Sample records for perryman don leroi

  1. André Leroi-Gourhan (25 août 1911–19 février 1986)

    OpenAIRE

    Soulier, Philippe

    2007-01-01

    André Leroi-Gourhan (25th August 1911 – 19th February 1986) A short biography of André Leroi-Gourhan is here presented, beginning in 1927, at the moment of his student years, until his retirement in 1982. It rests on a systematic analysis of his publications and on his personal and professional archives, collected and studied for the first time in 2001 when the author was temporally engaged by the CNRS. Going beyond the pure biography of events, such as those already presented in numerous po...

  2. Perryman Nuclear Power Plant. Site suitability--site safety report, volume I: chapters-sections 1.1, 1.2, 1.4, 1.6; 2.1, 2.2

    International Nuclear Information System (INIS)

    1977-01-01

    A site suitability report is submitted in support of the Baltimore Gas and Electric Company application for a limited early site review of a potential nuclear power plant. The Perryman Nuclear Power Plant site is located in northeastern Maryland on an arm of the Chesapeake Bay estuary approximately 17 miles east--northeast of Baltimore. The proposed plant is a two-unit light water reactor with a 3800 MW(t) power level for each unit. General descriptions of the site geography, demography, nearby facilities, and meteorology are presented

  3. Don Quijote y Hamlet

    Directory of Open Access Journals (Sweden)

    Lúdovik B. Osterc

    2002-12-01

    Hamlet está loco, es un alucinado que duda de sus propios sentidos. Para él existe sólo un lado negro de la existencia, su único objeto es llegar más pronto al descubrimiento del crimen. Es egocentrico, ne cree en nada, eternamente mira en su interior, se alimenta en su desprecio de sí mismo y su sufrimiento es mucho más doloroso.que aquel de Don Quijote. Don Quijote, al contrario, cree en el hombre y su futuro. Su ideal es implantar por la fuerza, la verdad, el bien y la justicia en la tierra. Para servir a su ideal, está dispuesto a sufrir todas las posibles privaciones. Representa la fe en la verdad. Es ridículo y quizás el más cómico tipo disenado jamás por un literato. Hamlet es el hijo del rey muerte, mientras que Don Quijote está pobre. Se hace los enemigos imaginarios y lucha contra ellos, mientras que Hamlet no cree en las ilusiones (siempre duda, y tampoco no combatiría si supiera que son sinónimos de opresores. Continua con la examinación de la actitud del pueblo o sus representantes hacia Don Quijote y Hamlet y viceversa. Polonia es el representante de las multitudes populares ante Hamlet, Sancho lo es ante su senor. El primero es de sano pensamiento y al mismo tiempo un viejo charalatán. Para él Hamlet no es tanto un loco como un nino y le parece inútil para la sociedad. Sancho Pansa está persuadido de que su senor está loco, pero le está leal hasta la muerte. Don Quijote simpatiza profundamente con el pueblo, pero la única persona con la que se entiende verdaderamente es Sancho Pansa (uno no puede vivir sin otro. La actitud de Hamlet es completamente diferente, él desprecia las multitudes populares, porque también desprecia a sí mismo. social: el tedio, el hastío, el descontento de la vida, desorientación espiritual y la eclipse de la fe, miéntras que Don Quijote encarna el mundo libre, bien estar y la felicidad de los seres humanos. Por eso y porque es un ideal el más humano, generoso, noble y elevado, el autor del

  4. Mimesis in Don Quixote

    Directory of Open Access Journals (Sweden)

    Giselle von der Walde

    2006-04-01

    Full Text Available Resumen:Frente a argumentos tomados de las poéticas neoaristotélicas que esgrime el canónigo para condenar los libros de caballerías, don Quijote pretende mostrar con su propio ejemplo, que ese tipo de lecturas no llevan a la locura ni al abandono de sí mismo, sino que, por el contrario, sacan lo mejor de la naturaleza de un individuo y lo hacen mejor persona. Este es el único tipo de imitación que Platón acepta en la República, pues más que un remedo o una suplantación, implica emulación. Este escrito se propone mirar, a partir del diálogo con el canónigo de Toledo (I, 49-50, cómo en sus conductas miméticas desde el comienzo de la obra, don Quijote entiende la imitación como emulación; en consecuencia se intenta demostrar que el efecto de la literatura en el caballero manchego parece ser el tipo de mimesis que Platón acepta en el libro III de la República.Abstract:Don Quijote demonstrates with the example of his own life the error made by the Canon of Toledo when the latter uses the arguments of the neo-Aristotelian poets to condemn the novels of chivalric romance. Quijote tries to show that reading the chivalric romances leads to neither madness nor the abandonment of the self, but, on the contrary, brings out the best in a person’s nature, and makes one a better person. This is the only type of imitation that Plato accepts in the Republic, because, unlike the mere copying of a person, or the substitution of one person for another, it implies a type of emulation. Starting with the dialogue of the Canon of Toledo (I, 49-50, this paper shows how, in his mimetic behavior, Don Quijote understands imitation as emulation. As a result, the paper shows that the effect of literature on the gentleman from La Mancha is the type of mimesis of which Plato approves in book III of the Republic.

  5. Don Isidoro Laverde Amaya

    Directory of Open Access Journals (Sweden)

    Carlos López Narváez

    1961-03-01

    Full Text Available A la calidad sustantiva de los polígrafos, -estirpe de los Vergara, Eduardo Posada, Gustavo Arboleda, Otero Muñoz, Samper Ortega, Gómez Restrepo para nombrar solo algunos de los que "nos han precedido con la señal de la fe", como dice el sacro ritual, y en el servicio de las Letras patrias- pertenece con mérito eximio el prócer de la bibliografía colombiana, don Isidoro Laverde Amaya.

  6. Trouble Don't Last

    Science.gov (United States)

    Pearsall, Shelley

    2004-01-01

    Even as a child, Pearsall questioned social injustice and prejudice. In her own community in Ohio and, as she grew, all over the world, she saw social inequities she could neither understand nor accept. Her novel "Trouble Don't Last," takes place during the era of the Underground Railroad. The chapter included here pulls us in…

  7. Kulturel liminalitet i Don Quixote

    DEFF Research Database (Denmark)

    Fastrup, Anne

    2007-01-01

    Med udgangspunkt i og i kontrast til nogle af hovedlinierne i den nyere litteratur om Don Quixote søger artiklen tilbage til de mere specifikke og lokale historiske forhold, som er romanens baggrund, bl.a. til Cervantes' »algierske erfaring« med tyrkisk fangenskab. Artiklen forsøger at kombinere ...

  8. Glucuronidation of deoxynivalenol (DON) by different animal species: identification of iso-DON glucuronides and iso-deepoxy-DON glucuronides as novel DON metabolites in pigs, rats, mice, and cows.

    Science.gov (United States)

    Schwartz-Zimmermann, Heidi E; Hametner, Christian; Nagl, Veronika; Fiby, Iris; Macheiner, Lukas; Winkler, Janine; Dänicke, Sven; Clark, Erica; Pestka, James J; Berthiller, Franz

    2017-12-01

    The Fusarium mycotoxin deoxynivalenol (DON) is a frequent contaminant of cereal-based food and feed. Mammals metabolize DON by conjugation to glucuronic acid (GlcAc), the extent and regioselectivity of which is species-dependent. So far, only DON-3-glucuronide (DON-3-GlcAc) and DON-15-GlcAc have been unequivocally identified as mammalian DON glucuronides, and DON-7-GlcAc has been proposed as further DON metabolite. In the present work, qualitative HPLC-MS/MS analysis of urine samples of animals treated with DON (rats: 2 mg/kg bw, single bolus, gavage; mice: 1 mg/kg bw, single i.p. injection; pigs: 74 µg/kg bw, single bolus, gavage; cows: 5.2 mg DON/kg dry mass, oral for 13 weeks) revealed additional DON and deepoxy-DON (DOM) glucuronides. To elucidate their structures, DON and DOM were incubated with human (HLM) and rat liver microsomes (RLM). Besides the expected DON/DOM-3- and 15-GlcAc, minor amounts of four DON- and four DOM glucuronides were formed. Isolation and enzymatic hydrolysis of four of these compounds yielded iso-DON and iso-DOM, the identities of which were eventually confirmed by NMR. Incubation of iso-DON and iso-DOM with RLM and HLM yielded two main glucuronides for each parent compound, which were isolated and identified as iso-DON/DOM-3-GlcAc and iso-DON/DOM-8-GlcAc by NMR. Iso-DON-3-GlcAc, most likely misidentified as DON-7-GlcAc in the literature, proved to be a major DON metabolite in rats and a minor metabolite in pigs. In addition, iso-DON-8-GlcAc turned out to be one of the major DON metabolites in mice. DOM-3-GlcAc was the dominant DON metabolite in urine of cows and an important DON metabolite in rat urine. Iso-DOM-3-GlcAc was detected in urine of DON-treated rats and cows. Finally, DON-8,15-hemiketal-8-glucuronide, a previously described by-product of DON-3-GlcAc production by RLM, was identified in urine of DON-exposed mice and rats. The discovery of several novel DON-derived glucuronides in animal urine requires adaptation of

  9. Don Germán

    OpenAIRE

    Juan Luis Mejía

    1991-01-01

    El veranillo de San Juan hace soportable el mediodía. Los "chorros d'oro" inundan de amarillo los antejardines del Prado. Las golondrinas veraneras invaden, al atardecer, los alrededores de la Biblioteca Departamental. Los voceadores de la suerte del paseo Bolívar claman a los cuatro vientos el número que cambiará su destino . Pero algo falta definitivamente en esta Barranquilla. De alguna manera la ciudad ya no es la misma. Falta Don Germán.

  10. [Don Quijote, a lucid mad].

    Science.gov (United States)

    Alonso Fernández, Francisco

    2004-01-01

    The case of a 50-year-old hidalgo who believed to be transformed into a knight-errant named Don Quijote is a megalomaniac systematized delusion of transformation of the self, a delusion of metamorphosis in reference to the patient's own identity. The outward projection of this syndrome produces some delusional misidentifications of others, things and animals and include elements of a persecutory delusion which increase the grandiosity of the self. At the same time the hidalgo was maniac with a pathway of bipolar disorder. The phenomenon of donquijotismo is described as the defence of wasted causes and Sancho Panza as an illiterate Sócrates.

  11. Don Germán

    Directory of Open Access Journals (Sweden)

    Juan Luis Mejía

    1991-01-01

    Full Text Available El veranillo de San Juan hace soportable el mediodía. Los "chorros d'oro" inundan de amarillo los antejardines del Prado. Las golondrinas veraneras invaden, al atardecer, los alrededores de la Biblioteca Departamental. Los voceadores de la suerte del paseo Bolívar claman a los cuatro vientos el número que cambiará su destino . Pero algo falta definitivamente en esta Barranquilla. De alguna manera la ciudad ya no es la misma. Falta Don Germán.

  12. Microbial biotransformation of DON: molecular basis for reduced toxicity

    Science.gov (United States)

    Pierron, Alix; Mimoun, Sabria; Murate, Leticia S.; Loiseau, Nicolas; Lippi, Yannick; Bracarense, Ana-Paula F. L.; Schatzmayr, Gerd; He, Jian Wei; Zhou, Ting; Moll, Wulf-Dieter; Oswald, Isabelle P.

    2016-07-01

    Bacteria are able to de-epoxidize or epimerize deoxynivalenol (DON), a mycotoxin, to deepoxy-deoxynivalenol (deepoxy-DON or DOM-1) or 3-epi-deoxynivalenol (3-epi-DON), respectively. Using different approaches, the intestinal toxicity of 3 molecules was compared and the molecular basis for the reduced toxicity investigated. In human intestinal epithelial cells, deepoxy-DON and 3-epi-DON were not cytotoxic, did not change the oxygen consumption or impair the barrier function. In intestinal explants, exposure for 4 hours to 10 μM DON induced intestinal lesions not seen in explants treated with deepoxy-DON and 3-epi-DON. A pan-genomic transcriptomic analysis was performed on intestinal explants. 747 probes, representing 323 genes, were differentially expressed, between DON-treated and control explants. By contrast, no differentially expressed genes were observed between control, deepoxy-DON and 3-epi-DON treated explants. Both DON and its biotransformation products were able to fit into the pockets of the A-site of the ribosome peptidyl transferase center. DON forms three hydrogen bonds with the A site and activates MAPKinases (mitogen-activated protein kinases). By contrast deepoxy-DON and 3-epi-DON only form two hydrogen bonds and do not activate MAPKinases. Our data demonstrate that bacterial de-epoxidation or epimerization of DON altered their interaction with the ribosome, leading to an absence of MAPKinase activation and a reduced toxicity.

  13. “Is that right?” – Don Favareau, Don Corleone & the semiotics of friendship

    DEFF Research Database (Denmark)

    Emmeche, Claus

    2017-01-01

    A chapter commenting specifically on John Poinsot's "Tractatus de Signis", John Deely's interpretation of Poinsot's mentioning of "friendship" as an example of a triadic relation, Don Favareau's contribution to the biosemiotic community, and Don Corleone as a symbol of a different kind of "friend......A chapter commenting specifically on John Poinsot's "Tractatus de Signis", John Deely's interpretation of Poinsot's mentioning of "friendship" as an example of a triadic relation, Don Favareau's contribution to the biosemiotic community, and Don Corleone as a symbol of a different kind...... of "friendship", and generally on the philosophy of friendship....

  14. Don Zhuanu otdajutsja tolko po ljubvi

    Index Scriptorium Estoniae

    2006-01-01

    Eestisse tuleb külla Roman Viktjuki Teater, 1. nov. mängitakse Vene Kultuurikeskuses Jean Genet' "Toatüdrukuid" (lavastaja Roman Viktjuk), 23. nov. etendatakse Eric-Emmanuel Scmitti "Don Juani viimast armastust" (lavastaja Roman Viktjuk)

  15. Don't Take This with That!

    Medline Plus

    Full Text Available ... Tobacco Products Drugs Home Drugs Resources for You Special Features Don't take this with that! Share ... Drug Interactions: What You Should Know More in Special Features Page Last Updated: 12/17/2015 Note: ...

  16. High and Crazy Niggers: Anti-Rationalism in Leroi Jones

    Science.gov (United States)

    Brown, Lloyd W.

    1974-01-01

    Suggests that the assumption that the theme of anti-rationalism in Jones is an attack on reason as such and that such a theme rests on an exclusive commitment to the irrational needs to be tested. (Author/AM)

  17. Don\\'t Ask, Don\\'t Tell: Ethical Issues Concerning Learning and ...

    African Journals Online (AJOL)

    Informed consent procedures and requirements must be clearly established and communicated. The learning and proficiency practices should be restricted to the staff that can truly benefit from the experience. The practice of 'don't ask, don't tell' is not an option. South African Journal of Family Practice Vol. 50 (4) 2008: pp.

  18. Guidelines : the do's, don'ts and don't knows of feedback for clinical education

    NARCIS (Netherlands)

    Lefroy, Janet; Watling, Chris; Teunissen, Pim W; Brand, Paul

    2015-01-01

    INTRODUCTION: The guidelines offered in this paper aim to amalgamate the literature on formative feedback into practical Do's, Don'ts and Don't Knows for individual clinical supervisors and for the institutions that support clinical learning. METHODS: The authors built consensus by an iterative

  19. Buscando a don Claudio Moyano

    Directory of Open Access Journals (Sweden)

    Juan González Ruiz

    2009-12-01

    Full Text Available (ES En el primer número de esta revista digital "Cabás", Antonio Montero Alcalde hizo un pormenorizado y útil análisis de la llamada Ley Moyano, la Ley de Instrucción Pública promulgada en 1857; la importancia de este texto legal en el desarrollo de la educación en España a lo largo de más de un siglo ha sido puesta de relieve en multitud de estudios históricos referidos a la época contemporánea. Nacido en una pequeña población zamorana el día 30 de octubre de 1809, la vida pública de don Claudio Moyano Samaniego, el firmante de la ley que lleva su nombre, se desarrolló básicamente en la corte madrileña; no obstante, rastrear en el entorno de su tierra natal algunos aspectos y circunstancias de su persona puede tener interés para completar la figura de una personalidad tan citada por su obra como desconocida por su vida. Y, al menos, sirve como curioso entretenimiento de un impenitente viajero a la búsqueda de huellas históricas de las escuelas de otros tiempos y de los hombres dedicados a ellas.

  20. Genio y figura de don Alfonso Reyes

    Directory of Open Access Journals (Sweden)

    Eduardo Carranza

    1968-04-01

    Full Text Available Entre varias, escojo esta: por sobria y conmovida a un tiempo. La escribió Juan Fernández Figueroa para su revista " Indice", de Madrid. Nos parece ver a don Alfonso en el rellano de la escalera -al fondo, sus libros; más allá, toda su vida, noble y pura- nos parece verle por última vez, inclinado ya sobre la baranda de la muerte. Tiene la calidad y el dinamismo de unos cuantos dibujos rápidos, nerviosos, esta imagen última de don Alfonso Reyes.

  1. Stability of DON and DON-3-glucoside during baking as affected by the presence of food additives.

    Science.gov (United States)

    Vidal, Arnau; Sanchis, Vicente; Ramos, Antonio J; Marín, Sonia

    2018-03-01

    The mycotoxin deoxynivalenol (DON) is one of the most common mycotoxins of cereals worldwide, and its occurrence has been widely reported in raw wheat. The free mycotoxin form is not the only route of exposure; modified forms can also be present in cereal products. Deoxynivalenol-3-glucoside (DON-3-glucoside) is a common DON plant conjugate. The mycotoxin concentration could be affected by food processing; here, we studied the stability of DON and DON-3-glucoside during baking of small doughs made from white wheat flour and other ingredients. A range of common food additives and ingredients were added to assess possible interference: ascorbic acid (E300), citric acid (E330), sorbic acid (E200), calcium propionate (E282), lecithin (E322), diacetyltartaric acid esters of fatty acid mono- and diglycerides (E472a), calcium phosphate (E341), disodium diphosphate (E450i), xanthan gum (E415), polydextrose (E1200), sorbitol (E420i), sodium bicarbonate (E500i), wheat gluten and malt flour. The DON content was reduced by 40%, and the DON-3-glucoside concentration increased by >100%, after baking for 20 min at 180°C. This confirmed that DON and DON-3-glucoside concentrations can vary during heating, and DON-3-glucoside could even increase after baking. However, DON and DON-3-glucoside are not affected significantly by the presence of the food additives tested.

  2. The rise of repeal: policy entrepreneurship and Don't Ask, Don't Tell.

    Science.gov (United States)

    Neff, Christopher L; Edgell, Luke R

    2013-01-01

    We report on policy entrepreneurship by Servicemembers Legal Defense Network (SLDN) and how its legislative strategies used mini-windows of opportunity to shift Capitol Hill perspectives of Don't Ask, Don't Tell (DADT) from political plutonium to an emerging issue requiring a second look. Four phases in the legislative history of DADT are identified: radioactive, contested, emerging, and viable. In all, this article argues that SLDN's entrepreneurship focused on contesting congressional sensibilities to wait or defer on repeal, maintained that every discharge was damaging and transitioned toward a post-repeal mind set. Finally, we illustrate the importance of these transitions by comparing SLDN's 2004 estimated vote count for the introduction of the Military Readiness Enhancement Act with the final 2010 voting results on the Don't Ask, Don't Tell Repeal Act.

  3. Guidelines: the do's, don'ts and don't knows of feedback for clinical education.

    Science.gov (United States)

    Lefroy, Janet; Watling, Chris; Teunissen, Pim W; Brand, Paul

    2015-12-01

    The guidelines offered in this paper aim to amalgamate the literature on formative feedback into practical Do's, Don'ts and Don't Knows for individual clinical supervisors and for the institutions that support clinical learning. The authors built consensus by an iterative process. Do's and Don'ts were proposed based on authors' individual teaching experience and awareness of the literature, and the amalgamated set of guidelines were then refined by all authors and the evidence was summarized for each guideline. Don't Knows were identified as being important questions to this international group of educators which if answered would change practice. The criteria for inclusion of evidence for these guidelines were not those of a systematic review, so indicators of strength of these recommendations were developed which combine the evidence with the authors' consensus. A set of 32 Do and Don't guidelines with the important Don't Knows was compiled along with a summary of the evidence for each. These are divided into guidelines for the individual clinical supervisor giving feedback to their trainee (recommendations about both the process and the content of feedback) and guidelines for the learning culture (what elements of learning culture support the exchange of meaningful feedback, and what elements constrain it?) Feedback is not easy to get right, but it is essential to learning in medicine, and there is a wealth of evidence supporting the Do's and warning against the Don'ts. Further research into the critical Don't Knows of feedback is required. A new definition is offered: Helpful feedback is a supportive conversation that clarifies the trainee's awareness of their developing competencies, enhances their self-efficacy for making progress, challenges them to set objectives for improvement, and facilitates their development of strategies to enable that improvement to occur.

  4. Don't Take This with That!

    Medline Plus

    Full Text Available ... Vaccines, Blood & Biologics Animal & Veterinary Cosmetics Tobacco Products Drugs Home Drugs Resources for You Special Features Don't take ... worth the squeeze…especially when combining grapefruit with medicines. While it can be part of a balanced ...

  5. Don't Take This with That!

    Medline Plus

    Full Text Available ... Vaccines, Blood & Biologics Animal & Veterinary Cosmetics Tobacco Products Drugs Home Drugs Resources for You Special Features Don't take ... more than fifty prescription and over-the-counter drugs known to the U.S. Food and Drug Administration ...

  6. Don Quijote en Canadá

    Directory of Open Access Journals (Sweden)

    Cristina Botella González

    2007-01-01

    Full Text Available Conocer a Cervantes y su obra.- Descubrir otros países y artistas.- Conocer al personaje de Don Quijote.- Familiarizarse con los personajes principales.- Relacionar la pintura y la literatura.- Desarrollar habilidades manuales y artísticas.- Potenciar la creatividad.

  7. Don't Take This with That!

    Medline Plus

    Full Text Available ... Submit search Popular Content Home Food Drugs Medical Devices Radiation-Emitting Products Vaccines, Blood & Biologics Animal & Veterinary Cosmetics Tobacco Products Drugs Home Drugs Resources for You Special Features Don't take this with that! Share Tweet Linkedin Pin it ...

  8. Don't Take This with That!

    Medline Plus

    Full Text Available ... Español Search FDA Submit search Popular Content Home Food Drugs Medical Devices Radiation-Emitting Products Vaccines, Blood & Biologics Animal & Veterinary Cosmetics Tobacco Products Drugs Home Drugs Resources for You Special Features Don't ...

  9. Dewey or Don't We?

    Science.gov (United States)

    Pendergrass, Devona J.

    2013-01-01

    "Dewey or don't we?" is the question that hundreds, if not thousands, of school librarians across the country are currently asking themselves. Do they throw out what is old but trusted for new organizational systems, or do they continue using the Dewey Decimal Classification (DDC) system and make changes and adjustments to the…

  10. Cervantes and the Lirical Poetry: Don Quixote

    Directory of Open Access Journals (Sweden)

    Fernando Romo Feito

    2012-12-01

    Full Text Available This essay examines the lyrical poems included in the first and the second part of Don Quixote. The different classes of poems are studied attending to its narrative context. But the poetry is also studied by relating it with metrical and aesthetical categories: Realism, Parody, Manierism…

  11. Sleep and sleep disorders in Don Quixote.

    Science.gov (United States)

    Iranzo, Alex; Santamaria, Joan; de Riquer, Martín

    2004-01-01

    In Don Quijote de la Mancha, Miguel de Cervantes presents Don Quixote as an amazing character of the 17th century who suffers from delusions and illusions, believing himself to be a medieval knight errant. Besides this neuropsychiatric condition, Cervantes included masterful descriptions of several sleep disorders such as insomnia, sleep deprivation, disruptive loud snoring and rapid eye movement sleep behaviour disorder. In addition, he described the occurrence of physiological, vivid dreams and habitual, post-prandial sleepiness--the siesta. Cervantes' concept of sleep as a passive state where all cerebral activities are almost absent is in conflict with his description of abnormal behaviours during sleep and vivid, fantastic dreams. His concept of sleep was shared by his contemporary, Shakespeare, and could have been influenced by the reading of the classical Spanish book of psychiatry Examen de Ingenios (1575).

  12. Fitness for Kids Who Don't Like Sports

    Science.gov (United States)

    ... Español Fitness for Kids Who Don't Like Sports KidsHealth / For Parents / Fitness for Kids Who Don' ... look for something new. Still Shopping for a Sport Some kids haven't found the right sport. ...

  13. Reading "Las Meninas": An Ekphrastic Approach to Teaching "Don Quijote"

    Science.gov (United States)

    Ortuno, Marian

    2012-01-01

    Reading and teaching "Don Quijote" present multiple challenges to twenty-first century students and instructors who are culturally and historically distanced from the seventeenth century. With "Las Meninas" serving as a visual lexicon for cuing correlative themes and events in "Don Quijote", the instructor, through an ekphrastic, interdisciplinary…

  14. Fungal flora and deoxynivalenol (DON) level in wheat from Jeddah ...

    African Journals Online (AJOL)

    This study aimed to explore the fungal flora along with the DON concentration in the collected wheat samples from Jeddah market to correlate between this flora and the detected DON. Whole grain wheat samples were collected from Jeddah market and this represents imported and locally produced wheat. The results ...

  15. Don Quixote og romangenren

    DEFF Research Database (Denmark)

    Kluge, Sofie

    Through the centuries Cervantes' Don Quixote (1605/1615) has delighted readers, inspired artists, and helped form our perception of early modern Spain. Moreover, it has played a major part in the development and theoretisation of one of the modern world's most central artistic forms: the novel. Don...

  16. DAYA ANTIBAKTERI EKSTRAK ETANOL DAUN SENGGANI (Melastoma affine D. Don

    Directory of Open Access Journals (Sweden)

    Ika Trisharyanti Dian Kusumowati

    2014-08-01

    Full Text Available Melastoma affine D. Don had some activities such as anthelmintic, antibacteria, antiinfiammation, antifungal, and antitumor. The aims of this research was determine antibacteria activity of ethanolic extract of Melastoma affine D. Don. The antimicrobial activity was tested by solid dilution method to get Minimum Inhibition Concentration (MIC. The compounds in Melastoma affine D. Don was analyzed by tube test method and Thin Layer Chromatography (TLC with chloroform : methanol : formic acid (8,5:1,5:0,5 as mobile phase and silica gel GF254 as stationary phase. The result showed ethanolic extract of Melastoma affine D. Don contains alkaloid, polyphenol, fiavonoid, saponin, and essential oil. The MIC of Senggani against Staphylococcus aureus was 2% and 3% against Escherichia coli and the extract could not inhibit Staphylococcus aureus and Escherichia coli multiresistant until concentration 7% extract ethanol. Keywords: Melastoma affine D. Don, Staphylococcus aureus, Escherichia coli

  17. Bioavailability of dissolved organic nitrogen (DON) in wastewaters from animal feedlots and storage lagoons

    Science.gov (United States)

    Dissolved organic nitrogen (DON) transport from animal agriculture to surface waters can lead to eutrophication and dissolved oxygen depletion. Biodegradable DON (BDON) is a portion of DON that is mineralized by bacteria while bioavailable DON (ABDON) is utilized by bacteria and/or algae. This stu...

  18. The President's pleasant surprise: how LGBT advocates ended Don't Ask, Don't Tell.

    Science.gov (United States)

    Frank, Nathaniel

    2013-01-01

    This study assesses the role of LGBT advocates in repealing the military's Don't Ask, Don't Tell policy in the U.S. Congress. It draws on the author's direct involvement with that effort as well as personal interviews and media evidence to consider the contributions of the Obama Administration, members of Congress, the media, and individuals and pressure groups in the repeal process. It argues that repeal succeeded not because of the effective implementation of a White House plan but because the pressure of LGBT advocates ultimately shattered several key obstacles including inadequate messaging and dysfunction and inertia among both politicians and interest groups in Washington. The article offers insight into the role of public pressure in forwarding social change.

  19. DON-induced changes in bone homeostasis in mink dams

    Directory of Open Access Journals (Sweden)

    Tomaszewska Ewa

    2017-09-01

    Full Text Available Introduction: The aim of the study was to investigate the mechanical and geometric properties as well as bone tissue and mineral density of long bones in mink dams exposed to deoxynivalenol (DON since one day after mating, throughout gestation (ca. 46 d and lactation to pelt harvesting. Material and Methods: Thirty clinically healthy multiparous minks (Neovison vison of the standard dark brown type were used. After the mating, the minks were randomly assigned into two equal groups: nontreated control group and DON group fed wheat contaminated naturally with DON at a concentration of 1.1 mg·kg-1 of feed. Results: The final body weight and weight and length of the femur did not differ between the groups. However, DON contamination decreased mechanical endurance of the femur. Furthermore, DON reduced the mean relative wall thickness and vertical wall thickness of the femur, while vertical cortical index, midshaft volume, and cross-sectional moment of inertia increased. Finally, DON contamination did not alter bone tissue density, bone mineral density, or bone mineral content, but decreased the values of all investigated structural and material properties. Conclusion: DON at applied concentration probably intensified the process of endosteal resorption, which was the main reason for bone wall thinning and the weakening of the whole bone.

  20. Don Joaquin García Monge

    Directory of Open Access Journals (Sweden)

    Agustín Rodríguez Garavito

    1958-11-01

    Full Text Available Los conocimos personalmente y tratamos de cerca en su amada ciudad de San José de Costa Rica. Casi diariamente íbamos por su casa. Una mansión grande, de vastos y sonoros corredores, arcones antiguos, libros apilados por doquier. Don Joaquín mantenía el timón de El Repertorio Americano, una de las más nobles publicaciones intelectuales del Continente. Dialogábamos con él sobre temas de mucha entidad, mientras la noche caía lentamente sobre este dulce país de porcelana tan grato a las veladas antiguas, aquellas donde se puede oír el latido del corazón como en el poema chino.

  1. Don quijote, Christelike geloof en natuurwetenskap 1

    Directory of Open Access Journals (Sweden)

    H. P.P. Lötter

    1987-03-01

    Full Text Available The story about Don Qulchote and the windmills is used in this article as an analogy to typify the debates that have taken place in history between natural science and representatives of Christian religion. The analogy is tested on debates that took place around Galileo. Darwin, Newton, Cuvier and the Big Bang theory. The analogy matches these debates quite well and this Is explained by the view that scientific claims to knowledge, and claims to knowledge based on Christian faith, belong to different categories and are thus not concurrents for the same truth. Gilbert Ryle's criticism on Descartes' mind-body dualism is used here to strengthen this argument. The article is concluded by pointing out in what ways one can engage in a meaningful debate on the nature of the relationship between science and Christian religion.

  2. We don't need another hero.

    Science.gov (United States)

    Badaracco, J L

    2001-09-01

    Everybody loves the stories of heroes like Martin Luther King, Jr., Mother Teresa, and Gandhi. But the heroic model of moral leadership usually doesn't work in the corporate world. Modesty and restraint are largely responsible for the achievements of the most effective moral leaders in business. The author, a specialist in business ethics, says the quiet leaders he has studied follow four basic rules in meeting ethical challenges and making decisions. The rules constitute an important resource for executives who want to encourage the development of such leaders among their middle managers. The first rule is "Put things off till tomorrow." The passage of time allows turbulent waters to calm and lets leaders' moral instincts emerge. "Pick your battles" means that quiet leaders don't waste political capital on fights they can't win; they save it for occasions when they really want to fight. "Bend the rules, don't break them" sounds easier than it is--bending the rules in order to resolve a complicated situation requires imagination, discipline, restraint, flexibility, and entrepreneurship. The fourth rule, "Find a compromise," reflects the author's finding that quiet leaders try not to see situations as polarized tests of ethical principles. These individuals work hard to craft compromises that are "good enough"--responsible and workable enough--to satisfy themselves, their companies, and their customers. The vast majority of difficult problems are solved through the consistent striving of people working far from the limelight. Their quiet approach to leadership doesn't inspire, thrill, or provide story lines for uplifting TV shows. But the unglamorous efforts of quiet leaders make a tremendous difference every day in the corporate world.

  3. Don't Panic! | NIH MedlinePlus the Magazine

    Science.gov (United States)

    ... of this page please turn Javascript on. Feature: Phobias and Anxiety Disorders Don't Panic! Past Issues / Fall 2010 Table of Contents Phobias and other anxiety disorders affect millions of Americans. ...

  4. Hyperbaric Oxygen Therapy: Don't Be Misled

    Science.gov (United States)

    ... on Minorities Don't Be Fooled By Health Fraud Scams Beware of Illegally Marketed Diabetes Treatments Products ... feeds Follow FDA on Twitter Follow FDA on Facebook View FDA videos on YouTube View FDA photos ...

  5. Will 3552 Don Quixote escape from the Solar System?

    Directory of Open Access Journals (Sweden)

    Suryadi Siregar

    2011-05-01

    Full Text Available Asteroid 1983 SA, well known as 3552 Don Quixote, is one of Near Earth Asteroids (NEAs which is the most probable candidate for the cometary origin, or otherwise as Jupiter-Family-Comets (JFCs. The aim of this study is to investigate the possibility of 3552 Don Quixote to be ejected from the Solar System. This paper presents an orbital evolution of 100 hypothetical asteroids generated by cloning 3552 Don Quixote. Investigation of its orbital evolution is conducted by using the SWIFT subroutine package, where the gravitational perturbations of eight major planets in the Solar System are considered. Over very short time scales (220 kyr relative to the Solar System life time (10 Gyr, the asteroid 3552 Don Quixote gave an example of chaotic motion that can cause asteroid to move outward and may be followed by escaping from the Solar System. Probability of ejection within the 220 kyr time scale is 50%.

  6. The Metabolic Fate of Deoxynivalenol and Its Acetylated Derivatives in a Wheat Suspension Culture: Identification and Detection of DON-15-O-Glucoside, 15-Acetyl-DON-3-O-Glucoside and 15-Acetyl-DON-3-Sulfate

    Directory of Open Access Journals (Sweden)

    Clemens Schmeitzl

    2015-08-01

    Full Text Available Deoxynivalenol (DON is a protein synthesis inhibitor produced by the Fusarium species, which frequently contaminates grains used for human or animal consumption. We treated a wheat suspension culture with DON or one of its acetylated derivatives, 3-acetyl-DON (3-ADON, 15-acetyl-DON (15-ADON and 3,15-diacetyl-DON (3,15-diADON, and monitored the metabolization over a course of 96 h. Supernatant and cell extract samples were analyzed using a tailored LC-MS/MS method for the quantification of DON metabolites. We report the formation of tentatively identified DON-15-O-β-D-glucoside (D15G and of 15-acetyl-DON-3-sulfate (15-ADON3S as novel deoxynivalenol metabolites in wheat. Furthermore, we found that the recently identified 15-acetyl-DON-3-O-β-D-glucoside (15-ADON3G is the major metabolite produced after 15-ADON challenge. 3-ADON treatment led to a higher intracellular content of toxic metabolites after six hours compared to all other treatments. 3-ADON was exclusively metabolized into DON before phase II reactions occurred. In contrast, we found that 15-ADON was directly converted into 15-ADON3G and 15-ADON3S in addition to metabolization into deoxynivalenol-3-O-β-D-glucoside (D3G. This study highlights significant differences in the metabolization of DON and its acetylated derivatives.

  7. Don Gonzalo Jimenez de Quesada. El Fundador

    Directory of Open Access Journals (Sweden)

    Alvaro López Pardo

    1989-09-01

    Full Text Available

    Discurso pronunciado por el Doctor Alvaro López Pardo Presidente de la Academia de Historia de Bogotá, al Consejo de Bogotá el día 6 de agosto de 1988. Sesión especial de los 450 años.

    Por el año de 1578, caminaba lentamente por las polvorientas calles del poblado de Mariquita, un anciano, casi octogenario, que mostraba en su piel huellas de un enfermedad que se decía era la de San Lázaro.

    Las gentes lo miraban pasar con una mezcla de respeto y de piedad. En su mirada, un tanto vaga, se podían apreciar destellos de la que fuera una recia personalidad. Esta pobre figura era nadie menos que el Mariscal Don Gonzalo Jiménez de Quesada.

    En esta población ardiente y lejana, cargado de deudas, sin techo propio, iba a morir el gran señor, el Gran Capitán, el Gran Aventurero que fundara ésta nuestra noble y muy leal Santa Fe de Bogotá, cuyos 450 años celebramos en este día.

    Parece increíble que en aquella época y con una agitada vida, Don Gonzalo hubiera llegado a tan avanzada edad, es muestra de la fuerza de una raza y del templo de su espíritu, que se sobreponía a todas las adversidades y contratiempos.

    ¿Qué recuerdos vendrían a la mente de este anciano cuando, sentado en una pobre silla de vaqueta, contempla el azul cielo del trópico? ¿Quizá su infancia en España, en Córdoba, donde naciera o en la imponente Granada de los moros, recuperada hacía unos años por la Reina Isabel. Viendo los jardines de la Alhambra, el Generalife y al fondo el blanco perpetuo de la Sierra Nevada. O vendría a su mente el paso del fúnebre cortejo de Felipe el Hermoso y su lunática viuda Doña Juana?

    Sería tal vez el periodo de su juventud, oyendo las aventuras de Cortés en la Conquista de México, en medio de una Europa convulsionada y con España como centro de la misma. O quizás cuando estudiaba leyes en Salamanca y se metía en pleitos que no siempre ganaba y como

  8. [Spanish neuroscience in times of Don Quixote].

    Science.gov (United States)

    Martín-Araguz, Antonio; Mikola, Yvett; Almendral-Doncel, Raquel; Campos-Bueno, Javier

    2016-02-16

    Miguel de Cervantes Saavedra published his immortal work Don Quixote of La Mancha in a time of crisis and decadence in Spain that occurred during the transition between the 16th and 17th centuries. In 2016 we commemorate the fourth centenary of the death of our distinguished man of letters, and thus in this article we analyse the status of Hispanic neuroscience, both in the Quixote itself and in other works by the most significant contemporary writers of that time. Despite the adverse historical circumstances, the shift from the Renaissance to the Baroque periods, in the Crown of Castile, was a flourishing period for literature (Spanish Golden Age) and other Hispanic arts (painting, sculpture, architecture and music), as well as bearing witness to a prodigious creativity in the field of neuroscience, including the field of natural philosophy. In his book Antoniana Margarita the physician Gomez Pereira laid the foundations for brain mechanism and the concept of conditioned reflexes several decades ahead of his time. The apothecary Miguel Sabuco also anticipated the concept of neurotransmission centuries ahead of his time in his New Philosophy. The physician Juan Huarte de San Juan was the founder of neuropsychology and experimental psychology, and his Examination of Men's Wits has been one of the most influential and widely translated scientific texts of all times. Its concepts are clearly reflected in Cervantes' Quixote. This analysis of Cervantes' work within the cultural setting of the book is intended as a homage to the immortal figure of our 'Prince of Wits' in the fourth centenary of his death.

  9. Viajando con Don Quijote en el siglo XXI

    Directory of Open Access Journals (Sweden)

    Odilíe Rojas-López

    2006-06-01

    Full Text Available Don Quixote has ridden with us for a long time now, and as if his fight against windmills were not enough, Don Quixote still has many more difficult situations to combat in the present times. Will the Knight of the Sad Figure accomplish this new deed? It is our challenge to find an answer to this inquiry. For this purpose, the author of this essay inserts the Knight of the Sad Figure in XXI century society. The author transforms the values, costumes and points of view of the times of the literary piece and establishes a series of relationships between the literary text, the main character and several current daily life situations. Don Quixote will certainly continue his fight against all the conditions we encounter nowadays. There is no doubt, then, that this knight still lives among us.

  10. Dostoyevski and Don Quijote: Poetics and Aesthetics of a Delusion

    Directory of Open Access Journals (Sweden)

    Tamara Djermanovic

    2015-12-01

    Full Text Available In Fedor Mikhailovich Dostoevsky’s body of work (1821-1881 one can find more than thirty references to Don Quixote; while some of them allude to the novel of Don Quixote itself, other ones refer to Cervantes’ hero as an archetypal figure. Since decades ago, the Russian literary criticism has been interested in the Russian quixotism – including Dostoevsky’s work – and important studies on this subject have been published recently. This study follows Dostoevsky’s references on La Mancha’s Knight as an independent figure of Cervantes’ novel, and the different symbolism Don Quixote’s figure has had in both Russian people and Russian intelligentsia.

  11. Distributed Observer Network (DON), Version 3.0, User's Guide

    Science.gov (United States)

    Mazzone, Rebecca A.; Conroy, Michael P.

    2015-01-01

    The Distributed Observer Network (DON) is a data presentation tool developed by the National Aeronautics and Space Administration (NASA) to distribute and publish simulation results. Leveraging the display capabilities inherent in modern gaming technology, DON places users in a fully navigable 3-D environment containing graphical models and allows the users to observe how those models evolve and interact over time in a given scenario. Each scenario is driven with data that has been generated by authoritative NASA simulation tools and exported in accordance with a published data interface specification. This decoupling of the data from the source tool enables DON to faithfully display a simulator's results and ensure that every simulation stakeholder will view the exact same information every time.

  12. Science and Fiction. On Don Quijote’s Epistemological Skepticism

    Directory of Open Access Journals (Sweden)

    Félix Schmelzer

    2016-11-01

    Full Text Available The present work seeks to analyze the representation of scientific knowledge in Cervantes’ Quixote, focusing on various passages that underline the scientific expertise of don Quixote himself. It is shown that the novel contains a subtle critique of science, based on an epistemological skepticism with regard to the arbitrariness of our world concepts. The characterization of don Quixote as a man of science even permits deducting that he suffers from a ‘double mental damage’, caused by the lecture of both books of cavalry and science. Cervantes thus would consider science to be fiction, a very modern point of view.

  13. Pia Petersen sous le signe de don Quichotte

    Directory of Open Access Journals (Sweden)

    Esther Bautista Naranjo

    2013-04-01

    Full Text Available This interview has been motivated by the Cervantean intertextuality of Pia Petersen’s (a French-speaking Danish author last novel, Le Chien de don Quichotte (2012. Departing from the values that the writer attributes to Cervantes’ work, I try to establish a connection with a specific critical trend in order to test, later on, to which extent this approach is used by the author to create a series of characters placed under the sign of don Quixote. Finally, I evaluate her novel’s relation with contemporary reality.

  14. Fuel elements assembling for the DON project exponential experience

    International Nuclear Information System (INIS)

    Anca Abati, R. de

    1966-01-01

    It is described the fuel unit used in the DON exponential experience, the manufacturing installments and tools as well as the stages in the fabrication.These 74 elements contain each 19 cartridges loaded with synterized urania, uranium carbide and indium, gold, and manganese probes. They were arranged in calandria-like tubes and the process-tube. This last one containing a cooling liquid simulating the reactor organic. Besides being used in the DON reactor exponential experience they were used in critic essays by the substitution method in the French reactor AQUILON II. (Author) 6 refs

  15. On Both Sides of the Atlantic: Re-Visioning Don Juan and Don Quixote in Modern Literature and Film

    OpenAIRE

    Perez, Karen Patricia

    2013-01-01

    The study analyzes contemporary literature and film based on two of the most universal characters in Spanish literature, Don Juan and Don Quixote, in both Spain and Hispanic America. Although both characters have undergone re-visioning from work to work through the centuries, it is the aim of this work to present the most salient characteristics of both archetypes in modern times only. The focus of this study is on works by well-known writers from Hispanic America and contemporary writers in ...

  16. Fallugia paradoxa (D. Don) Endl. ex Torr.: Apache-plume

    Science.gov (United States)

    Susan E. Meyer

    2008-01-01

    The genus Fallugia contains a single species - Apache-plume, F. paradoxa (D. Don) Endl. ex Torr. - found throughout the southwestern United States and northern Mexico. It occurs mostly on coarse soils on benches and especially along washes and canyons in both warm and cool desert shrub communities and up into the pinyon-juniper vegetation type. It is a sprawling, much-...

  17. IDEA: An Interdisciplinary Unit Comparing "Don Quixote" to "Hamlet."

    Science.gov (United States)

    Harris, Mary J. G.

    2001-01-01

    Describes an idea for teaching language through content-based instruction in which a high school Spanish class studying a shortened abridged version of Cervantes'"Don Quixote" and an English class reading Shakespeare's "Hamlet," did a simple comparative analysis of the two texts. (Author/VWL)

  18. Why Don't All Professors Use Computers?

    Science.gov (United States)

    Drew, David Eli

    1989-01-01

    Discusses the adoption of computer technology at universities and examines reasons why some professors don't use computers. Topics discussed include computer applications, including artificial intelligence, social science research, statistical analysis, and cooperative research; appropriateness of the technology for the task; the Computer Aptitude…

  19. "Don Kihotõ" nazõvajut lutshshih / Boris Tuch

    Index Scriptorium Estoniae

    Tuch, Boris, 1946-

    2003-01-01

    Lõppenud festivali FIPRESCI auhinna sai türgi film "Kauge" ("Uzak") : režissöör Nuri Bilge Ceylan. Rahvusvaheline filmiklubide föderatsioon (FICC) andis oma auhinna Don Quijote Andrei Zvjagintsevi filmile "Tagasitulek" ("Vozvrashtshenije") ja eriauhinna hiinlase Chen Kaige filmile "Üheskoos" ("Han ni zai ylki")

  20. Experiments in rooting bishop pine (Pinus muricata D. Don) cuttings

    Science.gov (United States)

    Constance I. Millar

    1987-01-01

    Presented here are results of rooting studies using hedges established from juvenile seedlings of "blue" and "green" foliaged bishop pine (Pinus muricata D. Don) from Mendocino and Sonoma Counties, California. Rootability, averaged over all clones and all setting dates, was 88%. The average time for 50% of the...

  1. 77 FR 64973 - Don W. Gilbert Hydro Power, LLC; Notice of Application Accepted for Filing With the Commission...

    Science.gov (United States)

    2012-10-24

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 14367-001] Don W. Gilbert...: Original Minor License. b. Project No.: 14367-001. c. Date filed: May 30, 2012. d. Applicant: Don W...(a)-825(r). (2006). h. Applicant Contact: Don W. Gilbert and DeAnn G. Somonich, Don W. Gilbert Hydro...

  2. CDC Vital Signs–Blood Pressure Medicines Don’t Work If People Don’t Take Them

    Centers for Disease Control (CDC) Podcasts

    2016-09-13

    Blood pressure medicines don’t work if people don’t take them. Learn how health care systems can work with patients to make taking medicines easier.  Created: 9/13/2016 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 9/13/2016.

  3. Blood Pressure Medicines Don’t Work If People Don’t Take Them PSA (:60)

    Centers for Disease Control (CDC) Podcasts

    This 60 second public service announcement is based on the September 2016 CDC Vital Signs report. Blood pressure medicines don’t work if people don’t take them. Learn how health care systems can work with patients to make taking medicines easier.

  4. To the Spanish Young People: Don Quixote Dreyfussard

    Directory of Open Access Journals (Sweden)

    Virginia Ramírez Martín

    2013-12-01

    Full Text Available In 1898, Spanish press take up part of its pages with a relevant international issue: the Dreyfus affair. The case was widely covered by Spanish newspapers, in special by Don Quijote, a Madrilenian satiric press, whose Director promoted a campaign in favour of Zola collecting signatures in order to the French litterateur was aware that Spain was close to him. This initiative is completed with a call to Spanish young people who is illustrated with a quixotic caricature. Cervantine character personifies the idea of justice getting to transmit during the Spanish crisis at the end of the nineteenth century the image of the nobleman forged by Spanish stereotypical, like a crusader fighting for a noble cause, thus turning Don Quixote into another dreyfussard.

  5. Don Quixote an Celia: the desire to live other lives

    Directory of Open Access Journals (Sweden)

    María Jesús Fraga Fernández-Cuevas

    2012-12-01

    Full Text Available The present study explores the parallelisms between Don Quixote and Elena Fortun’s novels Celia. First, it enumerates the various activities that prove the author’s interest in Cervantes and his work, as well as the possible intervention of her mentor, Maria Martinez Sierra, in the genesis of the child’s character. Both novels, of dialogical nature, share an episodic structure articulated by a weak storyline. Its protagonists are animated by the desire to live the lives of the characters of their favorite readings. They confuse fantasy and reality causing situations whose results are almost always adverse. If Don Quixote dies back to the reason, so will Celia, the girl, with her entry into adulthood by resigning her fantasies, which will be taken up by new generations of children.

  6. Don Carlos: Variations of Tragic from Schiller to Verdi

    Directory of Open Access Journals (Sweden)

    Fabio Vittorini

    2017-11-01

    Full Text Available In 1867 Giuseppe Verdi makes a grand opéra out of the dramatic poem Don Carlos, Infant von Spanien (1787 by Friedrich von Schiller. The workshop of Don Carlos lasts twenty years, from 1866 to 1886, when Verdi (reopens and closes several other workshops (Simon Boccanegra, La forza del destino, Aida, Requiem, Otello, creating a porous work in progress, whose analysis keeps giving us surprises. The libretto by Joseph Méry et Camille Du Locle, under the supervision of the composer, is a palimpsest where, under the official text referable to the common historical nucleus and its best known literary versions, some hidden or deleted heterogeneous texts appear, in a supranational, multilinguistic, intercultural and intertextual dimension, not always stirring along the road of a locatable derivation, of a voluntary imitation, but sometimes taking the shape of an unpredictable dissemination.

  7. Don Quijote in Nineteenth-Century English Theatre

    Directory of Open Access Journals (Sweden)

    J. A. Garrido Ardila

    2014-12-01

    Full Text Available This article brings to light a group of Cervantine English literary works hitherto unknown to present-day Cervantes studies: seven theatrical adaptations of Don Quixote (two anonymous ones in addition to those by Charles Dibdin, Joseph Moser, G. A. Macfarren, C. A. Maltby and P. Milton, a comedy with a Quixotic title (by George Dance, and five Quixotic fictions (two anonymous, in addition to those by Lily Spender, Maurice Hewlett and A. T. Quiller-Couch. Three of these plays, had been noted by Leopoldo Rius in 1899 (Moser, Macfarren, Maltby; the other four are presented for the first time here. In order to chart a fuller and more complete history of Don Quixote on the English stage, this article provides relevant information on those seven plays. An examination of these works reinforces the previous theses that underscore the essentially comical nature of Quixotic plays in nineteenth-century England, a fact of relevance in the study of the English reception of Don Quixote in the course of that century.

  8. Mineral characterisation of Don Pao rare earth deposit in Vietnam

    International Nuclear Information System (INIS)

    XuanBen, T.

    1998-01-01

    Full text: The Don Pao Rare Earth Deposit was discovered in 1959 in Phon Tho district, about 450km North-West of Hanoi capital. Geological work was conducted between 1959-95, resulting in 60 ore bodies of various sizes being identified. The ore bodies are irregularly shaped nests, lenses and veins hosted in the shear zone, at the margin of a Paeleogene aged syenite massif. The mineral composition of Don Pao Deposit is very complex, consisting of more than 50 minerals. Among them, basnaesite, parisite, fluorite and barite are the main constituent minerals of the ore. All the minerals were identified by the modern methods of mineralogical studies. Based on the constituent mineral ratios, four ore types have been distinguished in the deposit: 1. Rare earth ore containing over 5 percent of RE 2 O 3 . 2. Rare Earth-Barite ore containing 0.5 to 30 percent of RE 2 O 3 . 3. Rare Earth-Barite-Fluorite ore containing 1 to 5 percent of RE 2 O 3 . 4. Rare Earth bearing Fluorite ore containing 1 to 5 percent of RE 2 O 3 . According to the benefication test, the ores in Don Pao can be enriched to a concentrate of 60 percent of RE 2 O 3 with a recover of 75 percent

  9. Lesbian, Gay, Bisexual, and Transgender (LGBT) Service Members: Life After Don't Ask, Don't Tell.

    Science.gov (United States)

    Goldbach, Jeremy T; Castro, Carl Andrew

    2016-06-01

    Lesbian, gay, and bisexual service members can serve openly in the military with the repeal of the Don't Ask, Don't Tell policy. The fate of transgender service members remains uncertain as the policy preventing them from serving in the military remains under review. The health care needs of these populations remain for the most part unknown, with total acceptance and integration in the military yet to be achieved. In this paper, we review the literature on the health care needs of lesbian, gay, bisexual, and transgender (LGBT) service members, relying heavily on what is known about LGBT civilian and veteran populations. Significant research gaps about the health care needs of LGBT service members are identified, along with recommendations for closing those gaps. In addition, recommendations for improving LGBT acceptance and integration within the military are provided.

  10. The myth of the warrior: martial masculinity and the end of Don't Ask, Don't Tell.

    Science.gov (United States)

    Allsep, L Michael

    2013-01-01

    The image of the male warrior still dominates military culture, to the exclusion of women and homosexuals. Complicating the picture is a technological revolution that promises to widen the current gap between the myth and reality of the modern warrior even further. Nonetheless, despite long arguing that homosexuals were a direct threat to military culture and effectiveness, the Pentagon has largely treated the end of Don't Ask, Don't Tell as a policy matter. The difficulties still experienced by women in the armed services 40 years after they were first incorporated in significant numbers indicates that this response will be insufficient to address the deeper cultural issues. Gender issues implicate deeply held beliefs and values that persist even in the face of years of official admonishment and denial. Unless the military begins to transparently bridge the gap between the myth and reality of the modern warrior, military service without discrimination based on sexual orientation will remain an unachieved goal.

  11. Don Quixote Pond: A Small Scale Model of Weathering and Salt Accumulation

    Science.gov (United States)

    Englert, P.; Bishop, J. L.; Patel, S. N.; Gibson, E. K.; Koeberl, C.

    2015-01-01

    The formation of Don Quixote Pond in the North Fork of Wright Valley, Antarctica, is a model for unique terrestrial calcium, chlorine, and sulfate weathering, accumulation, and distribution processes. The formation of Don Quixote Pond by simple shallow and deep groundwater contrasts more complex models for Don Juan Pond in the South Fork of Wright Valley. Our study intends to understand the formation of Don Quixote Pond as unique terrestrial processes and as a model for Ca, C1, and S weathering and distribution on Mars.

  12. Don Quichotte, un don quichotte ? Déprogrammation d’un stéréotype

    Directory of Open Access Journals (Sweden)

    Marta Cuenca-Godbert

    2009-12-01

    Full Text Available En réaction à la publication de la suite apocryphe de Don Quichotte de la Manche, Cervantès utilise dans sa seconde partie les ressorts narratifs de la stéréotypie littéraire pour montrer à quel point son personnage diffère de ce qu'en a fait Alonso Fernández de Avellaneda, continuateur peu respectueux de sa personne et de son personnage. Le refus de voir en don Quichotte un simple stéréotype du chevalier errant chimérique est particulièrement manifeste dans la série d'aventures se déroulant au château des ducs, où don Quichotte, par sa renommée littéraire littéralement reconnue, est traité en chevalier par des personnages manipulateurs de situations, qui visent à produire chez lui des réactions programmées pour s’en amuser. Il apparaît alors que le simple agrégat d'ingrédients propres au stéréotype littéraire chevaleresque finit par ne pas produire l'issue escomptée.En la Segunda parte del Quijote, Cervantes reacciona ante la publicación de la de Alonso Fernández de Avellaneda, continuador poco respetuoso con la persona del autor primigenio y su personaje. Recurriendo a los procedimientos narrativos de la estereotipia literaria deja bien claro qué diferente resulta ser el personaje original respecto al del continuador. La negativa de ver a don Quijote como un mero estereotipo del caballero andante loco se pone particularmente de manifiesto en la serie de aventuras que transcurren en el palacio de los duques. Allí, los personajes reconocen literalmente la fama literaria de don Quijote. Generan, desde situaciones ficticias, tipos de tratamiento que se dispensarían a un verdadero caballero andante. Como resultado, se desencadena una serie de reacciones programadas con las que pretenden divertirse. Sin embargo, queda claro que la mera acumulación de ingredientes propios del estereotipo literario caballeresco no produce el resultado esperado.

  13. A Novel Source of DOC and DON to Watershed Soils

    Science.gov (United States)

    Aitkenhead-Peterson, J. A.

    2017-12-01

    A source of dissolved organic carbon (DOC) and nitrogen (DON) to soils and groundwater is that emanating from decomposing mammals. Although there is an increase in human donor facilities (body farms) in the USA and in mass mortality events (MME) worldwide, this injection of DOC and DON into watershed soils has received little attention. Studies at two human donor facilities in Texas, USA have revealed that the purge fluid associated with decomposition is extremely high in DOC and DON and migrates down the soil profile. Two studies were carried out 1) The southeast Texas Applied Forensic Science (STAFS) facility on an Alfisol with a saturated hydraulic conductivity of 331 mm hr-1 and 83% sand and 2) the Forensic Anthropology Research Facility (FARF) on Mollisols with a saturated hydraulic conductivity of 3.6-9.7 mm hr-1 and 28-33% sand. The numbers of days since donors were laid in the environment ranged from 219-680 d at STAFS and 306-960 d at FACTS. Purge can occur between 5 and 30 d dependent on the time of year the body is placed and the resultant phenomenon is termed cadaver decomposition island (CDI). Soil cores were taken at 5 cm increments to a depth of 30 cm in the sandy soil and 15 cm in the clayey/rocky soil. In the sandy soils, DOC concentrations were significantly higher in all the CDI soils when compared to control soils at depths of 15, 20, 25 and 30 cm and ranged from 121.7 µg g-1 (30 cm) to 167.6 µg g-1 (15 cm) in control soils and 461.9 µg g-1 (30 cm) to 660.4 µg g-1 (15 cm) in CDI soils, representing a three- to four-fold increase in DOC relative to control soils. DON in all CDI soils was not significantly higher than control soils until 30 cm depth and ranged from 9.9-32.3 µg g-1 in CDI soils and 121.7 µg g-1 in control soil, representing a two- to seven-fold increase in DON relative to control soils. DOC concentrations in control soils at the FARF site at 15 cm ranged 215-365 µg g-1 while in the CDI soils DOC was higher (range: 270

  14. Adrenalectomy for Cushing's syndrome: do's and don'ts.

    Science.gov (United States)

    Paduraru, D N; Nica, A; Carsote, M; Valea, A

    2016-01-01

    Aim. To present specific aspects of adrenalectomy for Cushing's syndrome (CS) by introducing well established aspects ("do's") and less known aspects ("don'ts"). Material and Method. This is a narrative review. Results. The "do's" for laparoscopic adrenalectomy (LA) are the following: it represents the "gold standard" for secretor and non-secretor adrenal tumors and the first line therapy for CS with an improvement of cardio-metabolic co-morbidities; the success rate depending on the adequate patients' selection and the surgeon's skills. The "don'ts" are large (>6-8 centimeters), locally invasive, malignant tumors requiring open adrenalectomy (OA). Robotic adrenalectomy is a new alternative for LA, with similar safety and conversion rate and lower pain drugs use. The "don'ts" are the following: lack of randomized controlled studies including oncologic outcome, different availability at surgical centers. Related to the sub-types of CS, the "do's" are the following: adrenal adenomas which are cured by LA, while adrenocortical carcinoma (ACC) requires adrenalectomy as first line therapy and adjuvant mitotane therapy; synchronous bilateral adrenalectomy (SBA) is useful for Cushing's disease (only cases refractory to pituitary targeted therapy), for ectopic Cushing's syndrome (cases with unknown or inoperable primary site), and for bilateral cortisol producing adenomas. The less established aspects are the following: criteria of skilled surgeon to approach ACC; the timing of surgery in subclinical CS; the need for adrenal vein catheterization (which is not available in many centers) to avoid unnecessary SBA. Conclusion. Adrenalectomy for CS is a dynamic domain; LA overstepped the former OA area. The future will improve the knowledge related to RA while the cutting edge is represented by a specific frame of intervention in SCS, children and pregnant women. Abbreviations: ACC = adrenocortical carcinoma, ACTH = Adrenocorticotropic Hormone, CD = Cushing's disease, CS

  15. Don't pay taxes, save your money!

    OpenAIRE

    Bradáč, Michal

    2011-01-01

    Bachelor thesis "Don't Pay Taxes, Save Your Money!" focuses on the impact of the existence of tax havens on private and public sector. On the theoretical level, it shows the attractivity of tax havens for sufficiently large firms that can afford to pay costs of tax planning and profit manipulations. On the empirical level, it shows that tax havens are really the most successful jurisdictions in attracting foreign investors. In the end, two models of tax competition are introduced in order to ...

  16. Digitaalisen markkinointiviestinnän suunnittelu Facebookissa: Ravintola Don Corleone

    OpenAIRE

    Dondych, Fanny

    2016-01-01

    Tämän opinnäytetyön tavoitteena oli kehittää viestintäsuunnitelma ravintolalle Don Corleone digi-taalisesta markkinointiviestinnästä Facebookissa. Työn tarkoituksena oli tehostaa ravintolan mark-kinointiviestintää Facebookissa, mikä johtaisi asiakkaiden lisääntymiseen ja sitä kautta liiketoimin-nan kasvuun. Sosiaalisen median palveluista viestintäkanavaksi valittiin Facebook toimeksiantajan toiveesta sekä Facebookin suuren suosion ja soveltuvuuden vuoksi. Facebookissa on valmiiksi pal-jon eri...

  17. Aspectos literarios de la obra de don Joan de Castellanos

    Directory of Open Access Journals (Sweden)

    Mario Germán Romero

    1966-09-01

    Full Text Available Capítulo XIV Voces castizas que no figuran en el diccionario de la academia (I Con el título de Dos mil quinientas voces castizas y bien autorizadas que piden lugar en nuestro léxico, publicó don Francisco Rodríguez Marín un interesante libro en Madrid, 1922. El erudito comentador del Quijote estudió cuidadosamente los autores españoles de los siglos XV, XVI y XVII.

  18. Signs of revision in Don Quixote, Part II

    Directory of Open Access Journals (Sweden)

    Gonzalo Pontón

    2016-11-01

    Full Text Available This article provides new evidences in favour of the hypothesis that Cervantes, after finishing Don Quixote, Part II, partially revised the original, introducing some significant changes and additions, mainly in the last chapters. The analysis of some narrative inconsistencies, that cannot be interpreted as mere mistakes but as significant textual traces, reveals a process of re-elaboration –a process that affects at least four sections of the novel. Most of the evidence gathered here suggests that this revision is closely linked to Avellaneda’s continuation, in the sense that Cervantes tried to challenge the apocriphal Quixote making last-time interventions in his own text.

  19. Don Favareau and the Road to Biosemiotic Transdisciplinarity

    DEFF Research Database (Denmark)

    Brier, Søren

    2017-01-01

    Don Favareau has been a dynamic contributor to the development of biosemiotics its organization, not only with his seminal book: Essential Readings in Biosemiotic: Anthology and Commentary from 2010, where he edited all his colleagues’ writings creating the history of biosemiotics. He has assumed...... the role of the modest and benevolent interdisciplinary integrator through his pervasive kindness and openness to all serious initiatives. Always he is considering where a specific contribution could fit in to the overall development of biosemiotics and pondering how a change in the foundation of science...

  20. Don, Betty and Jackie Kennedy: On Mad Men and Periodisation

    Directory of Open Access Journals (Sweden)

    Prudence Black

    2012-09-01

    Full Text Available Why is it that we watch Mad Men and think it represents a period? Flashes of patterned wallpaper, whiskey neat, babies born that are never mentioned, contact lining for kitchen drawers, Ayn Rand, polaroids, skinny ties, Hilton hotels, Walter Cronkite, and a time when Don Draper can ask ‘What do women want?’ and dry old Roger Sterling can reply ‘Who Cares?’ This essay explores the embrace of period detail in Mad Men finding it to be both loving and fetishistic, and belonging, like all period film, to the politics of the present.

  1. The Generation of 1898 and Cervantes : The invention of Don Quixote as a national symbol

    NARCIS (Netherlands)

    Storm, H.J.; Achiri, N.; Baraibar, A.; Schmelzer, F.K.E.

    2015-01-01

    Don Quixote became a Spanish national symbol thanks to the authors the Generation of 1898, such as Miguel de Unamuno, Azorín and Francisco Navarra Ledesma, who published their new interpretations during the 1905 commemoration of the publication of Cervantes', The Ingenious Gentleman Don Quixote of

  2. Le Don De Corps En Cote D\\'ivoire | Broalet | African Journal of ...

    African Journals Online (AJOL)

    Introduction Le don de corps qui permet de se procurer le matériel anatomique de dissection que constitue le cadavre humain n\\'existe pas en Afrique noire et notamment en Cote d\\' Ivoire. Objectif Recueillir des informations sur le don de corps à Abidjan. Méthode Les auteurs rapportent les informations recueillies au cours ...

  3. Blood Pressure Medicines Don’t Work If People Don’t Take Them PSA (:60)

    Centers for Disease Control (CDC) Podcasts

    2016-09-13

    This 60 second public service announcement is based on the September 2016 CDC Vital Signs report. Blood pressure medicines don’t work if people don’t take them. Learn how health care systems can work with patients to make taking medicines easier.  Created: 9/13/2016 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 9/13/2016.

  4. 77 FR 37031 - Don W. Gilbert Hydro Power, LLC; Notice of Application Tendered for Filing With the Commission...

    Science.gov (United States)

    2012-06-20

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 14367-001] Don W. Gilbert... No.: 14367-001. c. Date filed: May 30, 2012. d. Applicant: Don W. Gilbert Hydro Power, LLC. e. Name... Utility Regulatory Policies Act of 1978, 16 U.S.C. 2705, 2708.] h. Applicant Contact: Don W. Gilbert and...

  5. Microbial Detoxification of Deoxynivalenol (DON), Assessed via a Lemna minor L. Bioassay, through Biotransformation to 3-epi-DON and 3-epi-DOM-1.

    Science.gov (United States)

    Vanhoutte, Ilse; De Mets, Laura; De Boevre, Marthe; Uka, Valdet; Di Mavungu, José Diana; De Saeger, Sarah; De Gelder, Leen; Audenaert, Kris

    2017-02-13

    Mycotoxins are toxic metabolites produced by fungi. To mitigate mycotoxins in food or feed, biotransformation is an emerging technology in which microorganisms degrade toxins into non-toxic metabolites. To monitor deoxynivalenol (DON) biotransformation, analytical tools such as ELISA and liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) are typically used. However, these techniques do not give a decisive answer about the remaining toxicity of possible biotransformation products. Hence, a bioassay using Lemna minor L. was developed. A dose-response analysis revealed significant inhibition in the growth of L. minor exposed to DON concentrations of 0.25 mg/L and higher. Concentrations above 1 mg/L were lethal for the plant. This bioassay is far more sensitive than previously described systems. The bioassay was implemented to screen microbial enrichment cultures, originating from rumen fluid, soil, digestate and activated sludge, on their biotransformation and detoxification capability of DON. The enrichment cultures originating from soil and activated sludge were capable of detoxifying and degrading 5 and 50 mg/L DON. In addition, the metabolites 3-epi-DON and the epimer of de-epoxy-DON (3-epi-DOM-1) were found as biotransformation products of both consortia. Our work provides a new valuable tool to screen microbial cultures for their detoxification capacity.

  6. Microbial Detoxification of Deoxynivalenol (DON, Assessed via a Lemna minor L. Bioassay, through Biotransformation to 3-epi-DON and 3-epi-DOM-1

    Directory of Open Access Journals (Sweden)

    Ilse Vanhoutte

    2017-02-01

    Full Text Available Mycotoxins are toxic metabolites produced by fungi. To mitigate mycotoxins in food or feed, biotransformation is an emerging technology in which microorganisms degrade toxins into non-toxic metabolites. To monitor deoxynivalenol (DON biotransformation, analytical tools such as ELISA and liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS are typically used. However, these techniques do not give a decisive answer about the remaining toxicity of possible biotransformation products. Hence, a bioassay using Lemna minor L. was developed. A dose–response analysis revealed significant inhibition in the growth of L. minor exposed to DON concentrations of 0.25 mg/L and higher. Concentrations above 1 mg/L were lethal for the plant. This bioassay is far more sensitive than previously described systems. The bioassay was implemented to screen microbial enrichment cultures, originating from rumen fluid, soil, digestate and activated sludge, on their biotransformation and detoxification capability of DON. The enrichment cultures originating from soil and activated sludge were capable of detoxifying and degrading 5 and 50 mg/L DON. In addition, the metabolites 3-epi-DON and the epimer of de-epoxy-DON (3-epi-DOM-1 were found as biotransformation products of both consortia. Our work provides a new valuable tool to screen microbial cultures for their detoxification capacity.

  7. Vivisection au ralenti: Don DeLillo’s Point Omega

    Directory of Open Access Journals (Sweden)

    Ruxanda BONTILĂ

    2014-12-01

    Full Text Available Reading a Don DeLillo is like walking on glass, that is, you need hold your breath so that nothing could deter you from focusing on the mission, if you want to keep safe and mostly sound. The writer’s latest novel, Point Omega (2010, is no exception in that its author engages once more in the exercise of stripping away all surfaces so as to let us see into the terror of what he calls “makeshift reality”—his characters’ and ours. The claims I advance and substantiate in the essay, refer to (1 how a fluid chronology sustained by framing devices adds to the understanding of the construct of a novel/film in progress; (2 how the shifting narrative perspective ensures a vivisectionist’s look into the body of life/death/world. Don DeLillo’s novel is another terrifying X-ray of war/life/death as agonizing nothingness which literature in its ‘late-phase’ is meant to cure.

  8. Embryotoxicity Caused by DON-Induced Oxidative Stress Mediated by Nrf2/HO-1 Pathway

    Directory of Open Access Journals (Sweden)

    Miao Yu

    2017-06-01

    Full Text Available Deoxynivalenol (DON belongs to the type B group of trichothecenes family, which is composed of sesquiterpenoid metabolites produced by Fusarium and other fungi in grain. DON may cause various toxicities, such as cytotoxicity, immunotoxicity, genotoxicity as well as teratogenicity and carcinogenicity. In the present study, we focus on a hypothesis that DON alters the expressions of Nrf2/HO-1 pathway by inducing embryotoxicity in C57BL/6 mouse (5.0, 2.5, 1.0, and 0 mg/kg/day and BeWo cell lines (0 and 50 nM; 3 h, 12 h and 24 h. Our results indicate that DON treatment in mice during pregnancy leads to ROS accumulation in the placenta, which results in embryotoxicity. At the same time Nrf2/HO-1 pathway is up-regulated by ROS to protect placenta cells from oxidative damage. In DON-treated BeWo cells, the level of ROS has time–effect and dose–effect relationships with HO-1 expression. Moderate increase in HO-1 protects the cell from oxidative damage, while excessive increase in HO-1 aggravates the oxidative damage, which is called in some studies the “threshold effect”. Therefore, oxidative stress may be the critical molecular mechanism for DON-induced embryotoxicity. Besides, Nrf2/HO-1 pathway accompanied by the “threshold effect” also plays an important role against DON-induced oxidative damage in this process.

  9. Studies on phytosterol content of Parkia roxburgii G. Don.

    Directory of Open Access Journals (Sweden)

    DJADJAT TISNADJAJA

    2006-01-01

    Full Text Available Kedawung (Parkia roxburgii G. Don. is one of plants that originally could be found in almost all parts of Java Island. Due to lack of attention, at present situation this plant could be categorized as an endangered species. This plant species distributed widely in Africa. In several African countries, this plant has an important position either as food resource or alternative medicine. In Indonesia, traditionally kedawung tree often use as medicine, especially as part of “jamu gendong” formulation. This work was focused on the study of phytosterol content and it distribution. The research result show that almost all parts of kedawung tree have a significant content of phytosterol, which is dominated by beta-sitosterol. The highest beta-sitosterol content was founded in the stem of leaf (35.24% (w/w and pod (29.67% (w/w.

  10. Don Giovanni Goes to Prison: Teaching Opera behind Bars

    Directory of Open Access Journals (Sweden)

    Pierpaolo Polzonetti

    2016-12-01

    Full Text Available Teaching opera in prison presents challenges, such as limits imposed on printed and recorded material to study it, or the audio-visual technology in the classroom space, yet, no other experience can be so inspiring and rewarding for everybody involved. This essay focuses on teaching opera, in particular Mozart’s Don Giovanni, to imprisoned students in America. It addresses pedagogical challenges on how to teach opera in prison and advocates for the need to leave the ivory tower of academia and engage in social action. If opera is still perceived as an elitist art form, it is because it is artificially kept that way by being practiced, taught, studied, and promoted only among an exclusive sector of our population.

  11. Plantlets from encapsulated shoot buds of Catalpa ovata G. Don

    Directory of Open Access Journals (Sweden)

    Halina Wysokińska

    2014-01-01

    Full Text Available Shoot buds isolated from in vitro shoot cultures of Catalpa ovata G. Don were encapsulated using 3% sodium alginate with sucrose (3% and 50 mM calcium chloride. The morphogenic response of encapsulated buds was affected by such factors, like composition of the media and the presence of growth regulators. The highest frequency of plantlet germination from encapsulated buds (70% within 4 weeks was obtained on Woody Plant medium (WP (Lloyd and McCown 1980 containing indole-3-butyric acid (IBA (1 mg/l. The process was substantially inhibited by cold-storage (4oC of encapsulated buds. In this case, the frequency response ranged from 3% to 22% dependent on storage period (28 or 42 days and the presence of the paraffin coat covering the alginate capsules. The plantlets developed from both unstored and stored encapsulated buds of C. ovata were transplanted to soil and grew in pots to phenotypically normal plants.

  12. Efectos embriotóxicos de Picrosia longifolia Don (Asteraceae

    Directory of Open Access Journals (Sweden)

    Victor Benavides

    2014-06-01

    Full Text Available Se ha evaluado los probables efectos tóxicos del extracto acuoso de Picrosia longifolia Don “Achicoria” sobre el desarrollo de embriones preimplantacionales de ratón. Extracto acuoso de P. longifolia al 20%, 10% y 0% fue suministrado a ratonas preñadas hasta las 86 horas postcópula (hpc. Al evaluar el estadio embrionario se encontró que el extracto acuoso de P. longifolia al 10% y 20% causó retraso en el desarrollo embrionario. También se observó una disminución en la viabilidad embrionaria en los grupos tratados. Tanto la disminución de viabilidad como el retraso en el desarrollo se produjo en una forma dosis dependiente.

  13. Mission Analysis for the Don Quijote Phase-A Study

    Science.gov (United States)

    Cano, Juan L.; Sanchez, Mariano; Cornara, Stefania; Carnelli, Ian

    2007-01-01

    The Don Quijote Phase-A study is a definition study funded by ESA and devoted to the analysis of the possibilities to deflect a Near Earth Object (NEO) in the range of 300-800 m diameter. DEIMOS Space S.L. and EADS Astrium have teamed up within this study to form one of the three consortia that have analyzed these aspects for ESA. Target asteroids for the mission are 1989 ML, 2002 AT4 and Apophis. This paper presents the mission analysis activities within the consortium providing: low-thrust interplanetary rendezvous Orbiter trajectories to the target asteroids, ballistic interplanetary trajectories for the Impactor, Orbiter arrival description at the asteroids, Orbiter stable orbits characterization at the asteroid, deflection determination by means of a Radio Science Experiment (RSE) as well as the mission timelines and overall mission scenarios.

  14. Volatiles of Helichrysum italicum (Roth) G. Don from Croatia.

    Science.gov (United States)

    Zeljković, Sanja Ćavar; Šolić, Marija Edita; Maksimović, Milka

    2015-01-01

    Helichrysum italicum (Roth) G. Don is a flowering plant of the family Asteraceae. It is rich in oil that is used for different medicinal purposes and in fragrance industry. Volatile profile of four populations of H. italicum, collected from natural habitat in Dalmatia (Croatia), was analysed by capillary GC-MS. Sample from BraČ Island had α-trans-bergamotene (10.2%) and β-acoradiene (10.1%) as the majors, whereas sample collected on Biokovo Mt. was rich in neryl acetate (8.1%). β-Acoradiene was also the main constituent of sample collected near Tijarica, whereas rosifoliol (8.5%) was the most abundant constituent in sample collected near Makarska. Presented results show the influence of environmental conditions on chemical differentiation of the volatiles of H. italicum from Croatia.

  15. Scientific Communication for Positive Action: Do's and Don'ts

    Science.gov (United States)

    Sanquini, A.; Wood, M. M.

    2015-12-01

    Natural hazard presentations often highlight disasters that may ensue from natural processes when mitigation or preparedness actions are not taken. Examples include images of raging fires, collapsed buildings, and flooded urban areas. Research has shown that this makes presentations more interesting and more memorable. Such images are the stock and trade of disaster reporting by the media. Unfortunately, it may also trigger avoidance and denial in the audience, resulting in preparedness reduction; the opposite effect of what may have been intended by the speaker. Recent social research has provided insight into a better approach. The theory of communicating actionable risk posits that people will take action against hazards when they know what to do, think it would work, and know someone who did it. This approach was recently applied in an intervention designed to motivate earthquake-resistant construction in Kathmandu Valley, Nepal. Social theory further suggests that a tendency towards action is strengthened by hearing a consistent message over time, and by providing the audience with an appropriate opportunity to seek out relevant information. This presentation shows how, by taking this transdisciplinary step, scientists can make small changes in their hazard communication, thereby acting as positive influencers of change. A summary of "do's" and "don'ts" is given for reference. 1. Show examples of what to do. 2. Show effectiveness of actions. 3. Give sense of knowing someone who did it. 4. Deliver consistent message, repeatedly. 5. Give opportunity for more information. DON'T: 1. Make the disaster the star. 2. Contradict other communications.

  16. Don Bates: the medical historian as educator, activist, and historian of science.

    Science.gov (United States)

    Weisz, George

    2009-01-01

    The author outlines the academic and extra-academic career of Don Bates as a physician-historian, political activist, and creator of the interdisciplinary Department of Social Studies of Medicine at McGill University.

  17. Don't make me think: a common sense approach to Web usability

    National Research Council Canada - National Science Library

    Krug, Steve

    2006-01-01

    .... To ensure that your sites provide that experience, this guide from usability guru Krug distills his years of on-the-job experience into a practical primer on the do's and don'ts of good Web design...

  18. Have a Baby or Young Child With a Cold? Most Don't Need Medicines

    Science.gov (United States)

    ... Products For Consumers Home For Consumers Consumer Updates Most Young Children With a Cough or Cold Don' ... cold? It depends on the child’s age. Although most colds in children don’t have serious complications, ...

  19. ???????????? ? ?????????? ??????? ??????? ?? ??????? ???????????? ? ?????? ???????-??-???? // Advantages and disadvantages of franchise business opportunities in Rostov-on-don

    OpenAIRE

    Bugayan, S.A.; Filimonenko, I.

    2013-01-01

    ? ?????? ??????????? ???????? ???????????? ? ?????????? ??????????? ??????? ?? ??????? ???????????? ? ?????? ???????-??-???? ?? ??????? ????????? ????, ????????????? ??????? ???? ????? ??????? ? ?? ?????????? ??????????? ????????. In this article are considered main cons and pros of franchise business opportunities in Rostov-on-Don, using different businesses as an example,efficiency of this type of business and its future possibilities.

  20. Buy, don't build -- What does that mean for a software developer?

    International Nuclear Information System (INIS)

    Little, T.; Rahi, M.A.; Sinclair, C.

    1995-01-01

    The buzz phrase of the 1990's for the petroleum software industry has become ''buy, don't build.'' For an end user in an oil company, this generally means acquiring application software rather than developing it internally. The concept of buy, don't build can also apply for a software developer. Purchasing software toolkit components can expedite the development of an application as well as reduce future support requirements

  1. Mixing regime as a key factor to determine DON formation in drinking water biological treatment.

    Science.gov (United States)

    Lu, Changqing; Li, Shuai; Gong, Song; Yuan, Shoujun; Yu, Xin

    2015-11-01

    Dissolved organic nitrogen (DON) can act as precursor of nitrogenous disinfection by-products formed during chlorination disinfection. The performances of biological fluidized bed (continuous stirred tank reactor, CSTR) and bio-ceramic filters (plug flow reactor, PFR) were compared in this study to investigate the influence of mixing regime on DON formation in drinking water treatment. In the shared influent, DON ranged from 0.71mgL(-1) to 1.20mgL(-1). The two biological fluidized bed reactors, named BFB1 (mechanical stirring) and BFB2 (air agitation), contained 0.12 and 0.19mgL(-1) DON in their effluents, respectively. Meanwhile, the bio-ceramic reactors, labeled as BCF1 (no aeration) and BCF2 (with aeration), had 1.02 and 0.81mgL(-1) DON in their effluents, respectively. Comparative results showed that the CSTR mixing regime significantly reduced DON formation. This particular reduction was further investigated in this study. The viable/total microbial biomass was determined with propidium monoazide quantitative polymerase chain reaction (PMA-qPCR) and qPCR, respectively. The results of the investigation demonstrated that the microbes in BFB2 had higher viability than those in BCF2. The viable bacteria decreased more sharply than the total bacteria along the media depth in BCF2, and DON in BCF2 accumulated in the deeper media. These phenomena suggested that mixing regime determined DON formation by influencing the distribution of viable, total biomass, and ratio of viable biomass to total biomass. Copyright © 2014 Elsevier Ltd. All rights reserved.

  2. Science 101: Why Don't Spiders Stick to Their Own Webs?

    Science.gov (United States)

    Robertson, Bill

    2011-01-01

    This article explains why spiders don't stick to their webs. Spiders don't get stuck in their own webs (and they aren't immune to their own glue) because they use a combination of sticky and nonsticky threads (different glands for producing those), and the glue is in droplets that the spider can avoid but the prey can't. The spider's nervous…

  3. Effect of test exercises and mask donning on measured respirator fit.

    Science.gov (United States)

    Crutchfield, C D; Fairbank, E O; Greenstein, S L

    1999-12-01

    Quantitative respirator fit test protocols are typically defined by a series of fit test exercises. A rationale for the protocols that have been developed is generally not available. There also is little information available that describes the effect or effectiveness of the fit test exercises currently specified in respiratory protection standards. This study was designed to assess the relative impact of fit test exercises and mask donning on respirator fit as measured by a controlled negative pressure and an ambient aerosol fit test system. Multiple donnings of two different sizes of identical respirator models by each of 14 test subjects showed that donning affects respirator fit to a greater degree than fit test exercises. Currently specified fit test protocols emphasize test exercises, and the determination of fit is based on a single mask donning. A rationale for a modified fit test protocol based on fewer, more targeted test exercises and multiple mask donnings is presented. The modified protocol identified inadequately fitting respirators as effectively as the currently specified Occupational Safety and Health Administration (OSHA) quantitative fit test protocol. The controlled negative pressure system measured significantly (p < 0.0001) more respirator leakage than the ambient aerosol fit test system. The bend over fit test exercise was found to be predictive of poor respirator fit by both fit test systems. For the better fitting respirators, only the talking exercise generated aerosol fit factors that were significantly lower (p < 0.0001) than corresponding donning fit factors.

  4. Fuel elements assembling for the DON project exponential experience; Montaje de los elementos combustibles para la experiencia exponencial del proyecto DON

    Energy Technology Data Exchange (ETDEWEB)

    Anca Abati, R de

    1966-07-01

    It is described the fuel unit used in the DON exponential experience, the manufacturing installments and tools as well as the stages in the fabrication.These 74 elements contain each 19 cartridges loaded with synterized urania, uranium carbide and indium, gold, and manganese probes. They were arranged in calandria-like tubes and the process-tube. This last one containing a cooling liquid simulating the reactor organic. Besides being used in the DON reactor exponential experience they were used in critic essays by the substitution method in the French reactor AQUILON II. (Author) 6 refs.

  5. Authority as paradox: the transformations of Don Quijote.

    Science.gov (United States)

    Priel, Beatriz

    2006-12-01

    The author's contention is that the analysand's temporary attribution of authority to the analyst is inherent in the analytic situation; this is seen as a transitional and paradoxical form of authority pertaining neither to internal nor external reality, but dwelling in the analytic third. The author proposes a conceptualization of psychoanalytic authority as a form of aesthetic authority according to Gadamer's definitions. While the scientific and hermeneutic codes for the understanding of authority in psychoanalysis assume that the main issue at stake is the delimitation of the objectivity or the subjectivity of the analyst's knowledge, this aesthetic perspective centres on the analysand's attribution of a claim of truth to analytic interpretations, and on the experience of recognition. The experience of recognition of a possible truth is particular and context-bound, as well as self-transformational. A reading of three episodes from Cervantes's The history of Don Quixote de la Mancha illuminates the transitional and paradoxical character of aesthetic authority within a transformational dialogue. These episodes are read as dramatizations of different positions vis-à-vis the paradoxical authority that characterizes transformational dialogues.

  6. Simulating and Simulated Characters, Entangled in Don Quixote

    Directory of Open Access Journals (Sweden)

    Vicente Pérez de León

    2014-12-01

    Full Text Available One of the keys for understanding the ruling universe is the nature of the interconnected duality that governs it. It is neither completely monistic, neither absolutely nihilistic, according to the principle of the Platonic symploke (the Sophist 251, 255. The validity of the entanglement between “not everything are monisms” and the fact that reality is not completely “nihilist” will be used as a logic tool to understand the alternation in the understanding of the conclusions of the existences of several of the protagonists of the Quixote. On the one hand, it is the strange case of the suicidal shepherd Grisóstomo, in desperation for his loved Marcela, which is studied in the context of a similar case, the death of Anselmo in The Tale of Ill-advised Curiosity. On the other hand it is the case of the exemplary archetypical death of Don Quixote and his revival in Alonso Quijano “the good”, which presents a similar case of (misunderstanding of the symploke principle. In conclusion, the ontological tragedy arising from not understanding or questioning the Platonic principle of the symploke will contribute to explain the attachment, identification, and nature of the entanglement between reality and fiction in selected cervantine characters. This will be achieved by focusing in both their self-awareness as creative beings and their more or less voluntary inclusion in, or exclusion from, their own simulated realities.

  7. You Don't Look Like a Physicist

    Science.gov (United States)

    Santos, Antonio Carlos Fontes

    2017-12-01

    "You don't look like a physicist!" "Sorry, this bus only goes to the university, Sir." "Where are you going, sir?" "So, you are a university professor? But a substitute one, aren't you?" "OK, you're a professor, but do you do research?" As a person of color teaching physics in Brazil, those are some comments that I usually hear. They are consequences of stereotypes, prejudices, and discrimination, which are related but different ideas. Stereotypes indicate expectations and beliefs about an individual or a group, prejudice denotes feelings, and discrimination expresses behaviors. People are likely to be astonished whenever a Black person says that he or she is a physicist. This paper aims to raise awareness of the underrepresentation of Black physics professors and researchers in Brazil and how the lack of quality high school physics education impacts Black and poor students in Brazil. Finally, some considerations on how physics education can assist minority students in overcoming social barriers that contribute to their underrepresentation are presented.

  8. Hombres. Don Tomás Rueda Vargas

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    Boletin Cultural y Bibliográfico Banco de la República

    1958-07-01

    Full Text Available Quince años hizo el 25 de julio que desapareció de entre nosotros don Tomás Rueda Vargas. Su nombre, ejemplar por muchos conceptos, viene siempre nimbado de las virtudes cardinales que conformaron su tarea y su vida. Escritor nato,  sabía manejar el idioma con singular pericia sin caer en  rebuscamientos  ni  en  gongorismos. Su  pensamiento era diáfano por  lo cual no se  perdía en  el laberinto de  las palabras.   Apenas éstas eran  el dócil  instrumento para su dialéctica, para ese  generoso razo­  namiento intelectual que constituía el  Alfa  y el Omega   de  su diario batallar.

  9. Risk Acceptance Personality Paradigm: How We View What We Don't Know We Don't Know

    Science.gov (United States)

    Massie, Michael J.; Morris, A. Terry

    2011-01-01

    The purpose of integrated hazard analyses, probabilistic risk assessments, failure modes and effects analyses, fault trees and many other similar tools is to give managers of a program some idea of the risks associated with their program. All risk tools establish a set of undesired events and then try to evaluate the risk to the program by assessing the severity of the undesired event and the likelihood of that event occurring. Some tools provide qualitative results, some provide quantitative results and some do both. However, in the end the program manager and his/her team must decide which risks are acceptable and which are not. Even with a wide array of analysis tools available, risk acceptance is often a controversial and difficult decision making process. And yet, today's space exploration programs are moving toward more risk based design approaches. Thus, risk identification and good risk assessment is becoming even more vital to the engineering development process. This paper explores how known and unknown information influences risk-based decisions by looking at how the various parts of our personalities are affected by what they know and what they don't know. This paper then offers some criteria for consideration when making risk-based decisions.

  10. The Authors of the Ingenious Hidalgo Don Quixote of La Mancha

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    Branka Kalenić Ramšak

    2008-12-01

    Full Text Available Even today literary criticism still considers the novel Don Quixote the first modern European novel because it fundamentally changes both the concept of literary creation and the findings regarding literary reception. Miguel de Cervantes Saavedra published the first part of his chivalric novel in 1605 in Madrid with the title El ingenioso hidalgo don Quijote de la Mancha. He published the second part, titled El ingenioso caballero don Quijote de la Mancha, ten years later (i.e., in 1615, again in Madrid. Why did Cervantes change the title in the second part of his novel and thus transform Don Quixote the hidalgo ‘nobleman’ into Don Quixote the caballero ‘knight, nobleman, horseman’? In Spanish literature of Cervantes’ time, writers often borrowed texts from one another, wrote sequels to them, and reworked them into humorous poems, jocular one-act plays, or unusual parodies. The Baroque concept of imitation was not understood as plagiarism, but rather as a positive approach to creativity. One of Cervantes’ most enthusiastic imitators was Alonso Fernández de Avellaneda. He hated Cervantes, but loved Don Quixote so much that he wrote a sequel to it in the form of a chivalric novel. In 1614, Avellaneda published his novel titled Segundo tomo del ingenioso hidalgo don Quijote de la Mancha (The Second Part of the Ingenious Hidalgo of La Mancha in Tarragona. Who is hidden behind the name Alonso Fernández de Avellaneda? To date, literary history has not been able to establish with certainty who the author of this “second part” was; this work represents the greatest literary mystery of all time in Spanish literature. In the 1960s a theory developed among Cervantes experts that for now seems to be the most convincing in determining Avellaneda’s true identity. In his article “ El Quijote y los libros” (Don Quixote and Books of 1969, Martín de Riquer presented the first well-founded hypothesis claiming that the writer Alonso Fern

  11. Dissolved organic nitrogen (DON) profile during backwashing cycle of drinking water biofiltration.

    Science.gov (United States)

    Liu, Bing; Gu, Li; Yu, Xin; Yu, Guozhong; Zhang, Huining; Xu, Jinli

    2012-01-01

    A comprehensive investigation was made in this study on the variation of dissolved organic nitrogen (DON) during a whole backwashing cycle of the biofiltration for drinking water treatment. In such a cycle, the normalized DON concentration (C(effluent)/C(influent)) was decreased from 0.98 to 0.90 in the first 1.5h, and then gradually increased to about 1.5 in the following 8h. Finally, it remained stable until the end of this 24-hour cycle. This clearly 3-stage profile of DON could be explained by three aspects as follows: (1) the impact of the backwashing on the biomass and the microbial activity; (2) the release of soluble microbial products (SMPs) during the biofiltration; (3) the competition between heterotrophic bacteria and nitrifying bacteria. All the facts supported that more DON was generated during later part of the backwashing cycle. The significance of the conclusion is that the shorter backwashing intervals between backwashing for the drinking water biofilter should further decrease the DON concentration in effluent of biofilter. Crown Copyright © 2011. Published by Elsevier B.V. All rights reserved.

  12. MFS Transporters and GABA Metabolism Are Involved in the Self-Defense Against DON in Fusarium graminearum

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    Qinhu Wang

    2018-04-01

    Full Text Available Trichothecene mycotoxins, such as deoxynivalenol (DON produced by the fungal pathogen, Fusarium graminearum, are not only important for plant infection but are also harmful to human and animal health. Trichothecene targets the ribosomal protein Rpl3 that is conserved in eukaryotes. Hence, a self-defense mechanism must exist in DON-producing fungi. It is reported that TRI (trichothecene biosynthesis 101 and TRI12 are two genes responsible for self-defense against trichothecene toxins in Fusarium. In this study, however, we found that simultaneous disruption of TRI101 and TRI12 has no obvious influence on DON resistance upon exogenous DON treatment in F. graminearum, suggesting that other mechanisms may be involved in self-defense. By using RNA-seq, we identified 253 genes specifically induced in DON-treated cultures compared with samples from cultures treated or untreated with cycloheximide, a commonly used inhibitor of eukaryotic protein synthesis. We found that transporter genes are significantly enriched in this group of DON-induced genes. Of those genes, 15 encode major facilitator superfamily transporters likely involved in mycotoxin efflux. Significantly, we found that genes involved in the metabolism of gamma-aminobutyric acid (GABA, a known inducer of DON production in F. graminearum, are significantly enriched among the DON-induced genes. The GABA biosynthesis gene PROLINE UTILIZATION 2-2 (PUT2-2 is downregulated, while GABA degradation genes are upregulated at least twofold upon treatment with DON, resulting in decreased levels of GABA. Taken together, our results suggest that transporters influencing DON efflux are important for self-defense and that GABA mediates the balance of DON production and self-defense in F. graminearum.

  13. Consumption as Sign in Don DeLillo’s Cosmopolis

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    Seyyede Fateme Mirbabazade

    2013-11-01

    Full Text Available As one of the foremost American postmodern authors, Don DeLillo tends to focus on construction of postmodern subject’s consciousness through media, technology and consumption. Nevertheless, despite many affinities between Baudrillard and DeLillo, many researches which have been done on his works have failed to theoretically analyze them from Baudrillardian perspective. Although there is affinity between Baudrillard and DeLillo, there is dissimilarity as well. While Baudrillard believes that that there is no escape for individual from the ideology of the system, DeLillo claims that there is hope for change and revolution for the individuals by their action in society, particularly by the means of art, to be more  than a cog in the machine of ideology of system. Baudrillard, as one of the most influential postmodern theorists, defines consumption as organized control of sign and one of the many ways any subject is assimilated in any given society. For Baudrillard the logic of consumption is based on social differentiation. By the logic of social differentiation, individuals distinguish themselves and obtain social prestige and standing through the purchase and use of consumer goods. In his theorization about the concept of need and value, Baudrillard finds Marx’s logics of use value (utility and functionality and exchange value (economic value inadequate to include the whole function of an object and adds the logic of sign value. Baudrillard asserts that in consumption economic exchange value (money is transformed into sign exchange value (prestige, etc.; yet this functioning is maintained by the use value. The only way out of this dilemma, Baudrillard claims, is to return to symbolic exchange which is neither a conception nor an agency, but an act of exchange and a social relation and the only approach to real human communication and understanding. Therefore this research attempts to highlights those affinities in DeLillo’s first post-9

  14. Pharmacognostical studies of leaves of Combretum albidum G. Don

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    Ashish S Zalke

    2013-01-01

    Full Text Available Background: Combretum albidum Don belonging to family Combretaceae is an unexplored medicinal plant in the Indian medicinal system. According to ethnobotanical information, the leaves are used in the treatment of peptic ulcer and its fruits are used in diarrhoea and dysentery. Stem bark is used in the treatment of jaundice and skin diseases. The problem encountered in standardisation of this medicinal plant is its identification by source. Materials and Methods: The pharmacognostical studies were carried out in terms of organoleptic, macroscopic, microscopic, physicochemical, florescence and phytochemical analysis. Physicochemical parameters such as total ash, moisture content and extractive values are determined by World Health Organization guidelines. The microscopic features of leaf components are observed with Nikon lab photo device with microscopic units. Results: Macroscopically, the leaves are simple, obovate in shape, acuminate apex, entire margin and smooth surface. Microscopically, the leaves showed a large vascular strand that consists of thick walled xylem elements mixed with xylem fibres and phloem which is present in a thin layer along inner and outer portions of xylem. External to the xylem occur a thin line of sclerenchyma. Powder microscopy revealed glandular trichomes in the adaxial epidermal peelings also shows the non-glandular trichomes fairly common in powder and epidermis with anisocytic stomata. Vessels elements are narrow, long, cylindrical and dense multi-seriate bordered pits. Xylem fibres are thin and long, with thick walls, which are lignified. Preliminary phytochemical screening showed the presence of carbohydrate, glycoside, saponin, flavonoid, phytosterols and phenolic compounds. Conclusions: The results of the study can serve as a valuable source of pharmacognostic information as suitable standards for identification of this plant material in future investigations and applications.

  15. Don Quijote: de la prosa cervantina al teatro contemporáneo

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    Orazi, Veronica

    2016-12-01

    Full Text Available Study of six of the most recent and outstanding dramatisations (1999-2015 of Cervantes’s Don Quijote, such as Aventuras de Don Quijote, DQ. Don Quijote en Barcelona, El caballero de la triste figura, En un lugar de Manhattan, Elogio de la locura and En un lugar del Quijote. The analysis covers the main features of such adaptations: metanarration, metadrama, doubling of the narrative structure using other artistic languages (music, plastic arts, dance, etc., new technologies, genre hybridisation, transmediality, etc. The original text message, actualised and re-expressed by these modernisations, stands out as an atemporal one: the plays examined demonstrate its effectiveness in contemporary society and, according to the perspective of social theater, stimulate the reflection on them.

  16. Pemodelan Enterprise Architecture Sistem Informasi Akademik SMA PL Don Bosko Semarang Dengan Framework Zachman

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    Maria Alfonsa Chintia Dea Prananingrum

    2017-05-01

    Full Text Available Abstrak SMA PL Don Bosko Semarang belum dapat memanfaatkan teknologi komputer secara optimal karena masih menggunakan cara manual dalam pengelolaan berbagai macam data akademik sehingga memberikan masalah seperti lambatnya dalam pembuatan laporan yang menyulitkan kepala sekolah dalam pengambilan keputusan. Oleh sebab itu, SMA PL Don Bosko Semarang membutuhkan Sistem Informasi Akademik untuk memberikan kemudahan dalam mengelola berbagai macam data akademik secara terintegrasi serta memberikan layanan yang lebih baik kepada siswanya. Sebuah model architecture enterprise Sistem Informasi Akademik dibutuhkan agar meminimalisir kegagalan ketika menerapkan sistem tersebut sekaligus dapat berjalan sesuai kebutuhan di SMA PL Don Bosko Semarang. Metode analisis dalam penelitian ini menggunakan Framework Zachman yang memberikan pondasi dalam membantu menyediakan struktur dasar organisasi sehingga dapat mendukung perancangan dan pengembangan sistem informasi suatu organisasi. Hasil dari penelitian ini berupa blueprint (cetak biru pemodelan Sistem Informasi Akademik. Kata kunci— sistem informasi akademik, architecture enterprise, framework zachman, bluprint

  17. Don Quixote and Roque Guinart against the way of life of the influential people

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    Isabel M. Roger

    2016-11-01

    Full Text Available The apocryphal Second part of don Quixote altered many of the purposes of Cervantes. He changed the destination of his hero. As observed by don Quixote when visiting a printinghouse, its publication took place in Barcelona. The author gave prominence to a town as in picaresque novels. However, he did not modify his attitude towards the behaviour of the influential people, in keeping with Erasmus’ concept of stupidity. Surely, Cervantes reaffirmed his approach to the golden age through the presence of Roque Guinart, the only historical character who appears in the novel. This paper examines how the influential people behave in front of don Quixote, and how his performance is similar to that of Roque Guinart.

  18. The creator of the term 'anancasm' was Hungarian: Guyla Donáth (1849-1944).

    Science.gov (United States)

    Steinberg, Holger

    2015-12-01

    There is considerable confusion in the field of research on the history of psychiatry as to who created the term anancasm. This article seeks to clarify that the term was coined by the Hungarian psychiatrist Gyula Donáth, who was born in Baja, on the Danube, and worked mainly in Budapest. Donáth's publications reveal that his predominant sphere of interest and research was neurology and psychiatry. A number of his publications deal with epilepsy and obsessive-compulsive disorders. After a period of intensive research, during which he spent some time in Berlin at the clinic of neuroscientist Carl Westphal, Donáth proposed the term 'anancasm' in 1895 to describe compulsive mental processes. © The Author(s) 2015.

  19. Co-Contamination of DON and NIV in Domestic Flour in Japan: Survey, Intake, Reduction and Rapid Assay

    Science.gov (United States)

    Nivalenol (NIV) and Deoxynivalenol (DON) are trichothecene mycotoxins produced by Fusarium spp. that contaminate mainly cereal crops, such as wheat, barley, and maize. These mycotoxins are serious health hazards to humans and domestic animals. In Japan, there have been many reports of DON and NIV ...

  20. Evaluation of genetic toxicity of 6-diazo-5-oxo-l-norleucine (DON).

    Science.gov (United States)

    Kulkarni, Rohan M; Dakoulas, Emily W; Miller, Ken E; Terse, Pramod S

    2017-09-01

    DON (6-diazo-5-oxo-l-norleucine), a glutamine antagonist, was demonstrated to exhibit analgesic, antibacterial, antiviral and anticancer properties. The study was performed to characterize its in vitro and in vivo genetic toxicity potential. DON was tested in the bacterial reverse mutation assay (Ames test) using Salmonella typhimurium tester strains (TA98, TA100, TA1535 and TA1537) and Escherichia coli tester strain (WP2 uvrA) with and without S9 and also with reductive S9. In addition, DON was tested for the chromosome aberrations in Chinese hamster ovary (CHO) cells with or without S9 to evaluate the clastogenic potential. Furthermore, DON was also evaluated for its in vivo clastogenic activity by detecting micronuclei in polychromatic erythrocyte (PCE) cells in bone marrow collected from the male mice dosed intravenously with 500, 100, 10, 1 and 0.1 mg/kg at 24 and 48-h post-dose. The Ames mutagenicity assay showed no positive mutagenic responses. However, the in vitro chromosome aberration assay demonstrated dose dependent statistically positive increase in structural aberrations at 4 and 20-h exposure without S9 and also at 4-h exposure with S9. The in vivo micronucleus assay also revealed a statistically positive response for micronucleus formation at 500, 100 and 10 mg/kg at 24 and 48-h post-dose. Thus, DON appears to be negative in the Ames test but positive in the in vitro chromosome aberration assay and in the in vivo micronucleus assay. In conclusion, the results indicate DON is a genotoxic compound with a plausible epigenetic mechanism.

  1. RICKETS AT THE MEDICI COURT OF FLORENCE: THE CASE OF DON FILIPPINO (1577-1582).

    Science.gov (United States)

    Castagna, Maura; Giuffra, Valentina; Fattori, Silvia; Vitiello, Angelica; Caramella, Davide; Giustini, Davide; Fornaciari, Gino

    2014-01-01

    Among the children found in the crypt of the Grand Duke Giangastone in S. Lorenzo Basilica (Florence), the skeletal remains of a 5-year-old child still wearing his fine high social status clothing were recovered. This child of the Medici family was identified as Don Filippino (1577-1582), son of the Grand Duke Francesco I (1541-1587) and Giovanna from Austria (1547 - 1578). The prince showed several pathological deformities of the cranial and post-cranial skeleton, including enlargement of the cranium, thinning of the cranial vault bones (craniotabes), platybasia and marked bending of femora, tibiae and fibulae. Differential diagnosis suggests that Don Filippino was affected by rickets. The occurrence of this metabolic disease related to vitamin D deficiency in a Renaissance high social class individual can be explained by the practice of very prolonged breast-feeding, up until two years of age. Maternal milk contains insufficient vitamin D ratios and retarded weaning severely exposes children to a higher risk of developing rickets, especially if dietary habits are combined with inadequate exposure to sunlight. Historical sources describe Don Filippino as frail and sickly, with frequent illnesses and persistent slight fevers, and it can be supposed that the child was frequently confined indoors, especially in the cold season. Integration of osteoarchaeological evidence with historical documentation suggests that bone lesions observed in the skeletal remains of Don Filippino are compatible with a diagnosis of rickets, caused by the custom of prolonged breast-feeding associated with inadequate sunlight exposure to sunlight. Historical sources describe Don Filippino as frail and sickly, with frequent illnesses and persistent slight fevers, and it can be supposed that the child was frequently confined indoors, especially in the cold season. Integration of osteoarchaeological evidence with historical documentation suggests that bone lesions observed in the skeletal

  2. Organ Damage and Hepatic Lipid Accumulation in Carp (Cyprinus carpio L. after Feed-Borne Exposure to the Mycotoxin, Deoxynivalenol (DON

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    Constanze Pietsch

    2014-02-01

    Full Text Available Deoxynivalenol (DON frequently contaminates animal feed, including fish feed used in aquaculture. This study intends to further investigate the effects of DON on carp (Cyprinus carpio L. at concentrations representative for commercial fish feeds. Experimental feeding with 352, 619 or 953 μg DON kg−1 feed resulted in unaltered growth performance of fish during six weeks of experimentation, but increased lipid peroxidation was observed in liver, head kidney and spleen after feeding of fish with the highest DON concentration. These effects of DON were mostly reversible by two weeks of feeding the uncontaminated control diet. Histopathological scoring revealed increased liver damage in DON-treated fish, which persisted even after the recovery phase. At the highest DON concentration, significantly more fat, and consequently, increased energy content, was found in whole fish body homogenates. This suggests that DON affects nutrient metabolism in carp. Changes of lactate dehydrogenase (LDH activity in kidneys and muscle and high lactate levels in serum indicate an effect of DON on anaerobic metabolism. Serum albumin was reduced by feeding the medium and a high dosage of DON, probably due to the ribotoxic action of DON. Thus, the present study provides evidence of the effects of DON on liver function and metabolism.

  3. Organ Damage and Hepatic Lipid Accumulation in Carp (Cyprinus carpio L.) after Feed-Borne Exposure to the Mycotoxin, Deoxynivalenol (DON)

    Science.gov (United States)

    Pietsch, Constanze; Schulz, Carsten; Rovira, Pere; Kloas, Werner; Burkhardt-Holm, Patricia

    2014-01-01

    Deoxynivalenol (DON) frequently contaminates animal feed, including fish feed used in aquaculture. This study intends to further investigate the effects of DON on carp (Cyprinus carpio L.) at concentrations representative for commercial fish feeds. Experimental feeding with 352, 619 or 953 μg DON kg−1 feed resulted in unaltered growth performance of fish during six weeks of experimentation, but increased lipid peroxidation was observed in liver, head kidney and spleen after feeding of fish with the highest DON concentration. These effects of DON were mostly reversible by two weeks of feeding the uncontaminated control diet. Histopathological scoring revealed increased liver damage in DON-treated fish, which persisted even after the recovery phase. At the highest DON concentration, significantly more fat, and consequently, increased energy content, was found in whole fish body homogenates. This suggests that DON affects nutrient metabolism in carp. Changes of lactate dehydrogenase (LDH) activity in kidneys and muscle and high lactate levels in serum indicate an effect of DON on anaerobic metabolism. Serum albumin was reduced by feeding the medium and a high dosage of DON, probably due to the ribotoxic action of DON. Thus, the present study provides evidence of the effects of DON on liver function and metabolism. PMID:24566729

  4. La reciprocidad y el don no son la misma cosa

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    Ricardo Gabriel Abduca

    2007-12-01

    Full Text Available El autor se propone mostrar por qué la noción de reciprocidad, aunque ha sido muchas veces tomada como sinónimo del fenómeno de intercambios de dones, corresponde a diversas situaciones sociales, por lo cual tiene poca utilidad descriptiva y explicativa. Examina algunos hitos de la historia antropológica, mostrando que más que un concepto, 'reciprocidad' es un palimpsesto sobre el cual, de Durkheim a Polanyi, se han ido escribiendo variadas nociones. En cambio, sugiere una definición de don más estricta, cercana a las ideas de Mauss y acorde con los avances de la etnografía y la teoría contemporánea. Sugiere distinguir entre circuitos cerrados de dones, donde circulan bienes de consumo final, y circuitos abiertos, donde los dones que circulan condensan el conjunto de las relaciones sociales.O objetivo deste texto é mostrar que a expressão 'reciprocidade', ainda foi considerada como sinônimo de 'câmbio de domes', é outra coisa. O autor sugere um breve esquema de alguns marcos do desenvolvimento da noção de 'reciprocidade' em a teoria antropológica, mostrando que o sentido dela expressão foi mudando até assemelhar um palimpsesto com múltiplas rescritas, no processo que vá de Durkheim a Polanyi. Defende um conceito de dom próximo às idéias de Mauss e a certos avances dela etnografia contemporânea e a teoria social. Distingue deus tipos de circuitos de circulação de domes: fechados, onde circulam bens de consumação direita, e apertos, onde circulam certo tipo de bens que condensam o conjunto das relações sociais.The aim of this text is to show how the notion of 'reciprocity', although have been considered a synonymous of gift exchange, veils different social situations. A brief survey of the history of the use of the word shows how 'reciprocity', from Durkheim to Polanyi, seems as a palimpsest of various notions. Although, he essays a defense of a concept of 'gift' related to the Maussian texts, and closer to some

  5. Un curioso coleccionista del siglo XVII: don Manuel de Porras

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    Agulló y Cobo, Mercedes

    2003-09-01

    Full Text Available Art collecting - an avocation almost exclusive to royalty in Spain - has not had representatives among those who did not belong to the high nobility, not even among artists themselves. In many cases, the word "collection" has been applied to what in reality were mere lists of patrimonial properties. For all of the above, it is especially noteworthy to encounter someone who neither belonged to an elevated class nor was a painter, but who managed to unite, at great personal sacrifice, an important art collection. Manuel de Porras owned interesting and a relatively large number of paintings, sculptures and prints, some of them extremely valuable. As a good collector, in order to avoid the dispersion of these works, he donated them to the Shod Trinitarians in Madrid and the Oratory of Saint Philip Neri in Alcalá, but unfortunately, in spite of his good intentions, nothing has survived.

    El coleccionismo —afición casi exclusiva de Reyes en España— no ha tenido representantes entre personas que no pertenecieran a la alta nobleza, ni entre los propios artistas. En muchos casos lo que se ha venido llamando colecciones son sólo relación de bienes patrimoniales. Por ello, resulta más llamativo encontrar alguien que, sin pertenecer a una clase elevada ni ser artista, lograra reunir —aun a costa de grandes sacrificios que le llevaron al extremo de ser enterrado de limosna— una tan importante colección de obras de arte como el personaje objeto de este artículo: Manuel de Porras, quien contaba con un interesante y elevado (para un particular sin títulos número de pinturas y esculturas, y un importantísimo número de dibujos y estampas, algunas valiosísimas y de alto precio. Desgraciadamente, aunque lo donó —como buen coleccionista, para evitar su dispersión— a los Trinitarios calzados de Madrid y al Oratorio de San Felipe Neri de Alcalá, nada de ello ha llegado a nuestros días.

  6. The I Don't Know Option in the Vocabulary Size Test

    Science.gov (United States)

    Zhang, Xian

    2013-01-01

    The current study evaluates guessing behaviors in a vocabulary size test (VST) and examines whether including an "I don't know" in a VST may have an impact on the results of the test. One-hundred-fifty first-year students at a university in China took part in the study. They were randomly assigned to three groups. Each group took a…

  7. 77 FR 21556 - Don Pedro Hydroelectric Project: Turlock Irrigation District; Modesto Irrigation District...

    Science.gov (United States)

    2012-04-10

    .... Date and Time of Meeting: Tuesday, April 17, 2012. 9 a.m.-5 p.m. b. Place: Holiday Inn, Sacramento-Capitol Plaza, 300 J Street, Sacramento, CA 95814, 916-446-0100. c. FERC Contact: Stephen Bowler, Don... technical conference would be an all day meeting in Sacramento, California on April 17, 2012. The notice...

  8. Tiffany Diamonds and Classical Music as Influences on the Performance of "Don Juan in Hell".

    Science.gov (United States)

    Johnson, Jim

    This paper analyzes Paul Gregory's 1951 production of "Don Juan in Hell," now considered to be a seminal work in the development of professional and educational readers theatre. The paper contends that the production, which presented a nondramatic work without the usual emphasis on design and spectacle, forced a reexamination of the role…

  9. Spendere meno, spendere meglio: una proposta panottica di J.-C. Guédon

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    Maria Chiara Pievatolo

    2013-06-01

    Full Text Available J.-C. Guédon ha commentato la nostra campagna di crowdsourcing in merito alle spese delle biblioteche sulla mailing list Nexa. Offriamo, qui di seguito, la versione italiana delle sue osservazioni – che presuppongono un mondo accademico molto diverso da quello impostoci...

  10. Dr. S. Donald (Don) Stookey (1915-2014): Pioneering Researcher and Adventurer

    Science.gov (United States)

    Beall, George H.

    2016-07-01

    Don Stookey, the father of glass-ceramics, was a pioneer in inducing and understanding internal nucleation phenomena in glass. His early work on dense opal glasses and photosensitive precipitation of gold and silver in glass led to an amazing series of inventions: Fotalite, a photosensitive opal, chemically machined Fotoform and Fotoceram, and TiO2-nucleated Pyroceram products including missile nosecones and oven-proof cookware. He received a basic patent on glass-ceramics, which was contested and affirmed in court. Don was able to demonstrate a clear photochromic glass that showed reversible darkening for thousands of cycles. This material became a fixture in the ophthalmic industry. He went on to invent a full-color polychromatic glass, capable of yielding a permanent patterned and monolithic stained glass. In his life outside science, Don chaired an interfaith group that founded a home for the elderly in Corning. He was also a wilderness enthusiast, surviving a plane crash in the Arctic and two boat capsizings. Even in his later years, he continued fishing off the coast of Florida and on Lake Ontario and went solo on a trip to the Patagonian Andes. Don Stookey was a special person by any measure: an unassuming optimist, eminent scientist and inventor, adventurer, and a beloved family man. Introduction

  11. What Catholic Educators Can Learn from the Radical Christianity and Critical Pedagogy of Don Lorenzo Milani

    Science.gov (United States)

    Grech, Michael; Mayo, Peter

    2014-01-01

    This paper explores some of the ideas expressed in or associated with the work of Don Lorenzo Milani and the School of Barbiana and discusses them in the light of the teachings of the gospels. It draws out the implications of these ideas for a critical education in the Christian spirit. The focus throughout is on Christian education for social…

  12. Inheritance of allozyme variants in bishop pine (Pinus muricata D.Don)

    Science.gov (United States)

    Constance I. Millar

    1985-01-01

    Isozyme phenotypes are described for 45 structural loci and I modifier locus in bishop pine (Pinus muricata D. Don,) and segregation data are presented for a subset of 31 polymorphic loci from 19 enzyme systems. All polymorphic loci had alleles that segregated within single-focus Mendelian expectations, although one pair of alleles at each of three...

  13. DON JUAN: THE DISCOURSE OF SEDUCTION AS AN EXERCISE OF POWER

    Directory of Open Access Journals (Sweden)

    Kristina Stankevičiūtė

    2016-10-01

    Full Text Available The figure of Don Juan that emerged in Spanish baroque synthesised several important cultural issues related to the phenomenon of seduction, a subject of great social controversy since the very beginning of the Christian era. The present article analyses one of the fundamental parts of the universal appeal of the Don Juan figure – the discourse of seduction, considering it from the social and cultural point of view. The traditional discussion of the subject focuses on the contents of the discourse whereas the present article emphasises the implications rather than the contents, grounding its arguments on Jean Baudrillard’s theory of seduction, which claims that it is the signs and the play of signs that are important in seduction, not their meanings. The seduction discourse is seen as a means to exercise power on the women that Don Juan deals with as well as on the audience who gets involved into the discourse creation process. The article concludes with a claim that Don Juan is a figure of social domination, and his discourse is a means to achieve it.

  14. Why I don't kill myself : [poems] / Paul-Eerik Rummo

    Index Scriptorium Estoniae

    Rummo, Paul-Eerik, 1942-

    2003-01-01

    Autori lühitutvustus lk. 262. Sisu: Why I don't kill myself ; The sky stoops over the earth ; Clinging ; Crooning. Orig.: Miks ma end ära ei tapa ; "Taevas on kummargil üle maa..." ; Kinni hoidmas ; Poolüminal

  15. Dr. S. Donald (Don Stookey: (1915-2014: Pioneering Researcher and Adventurer

    Directory of Open Access Journals (Sweden)

    George Halsey Beall

    2016-08-01

    Full Text Available Don Stookey was a special person by any measure: an unassuming optimist, eminent scientist and inventor, adventurer, and a beloved family man. Don Stookey, the father of glass-ceramics, was a pioneer in inducing and understanding internal nucleation phenomena in glass. His early work on dense opal glasses and photosensitive precipitation of gold and silver in glass led to an amazing series of inventions: Fotalite®, a photosensitive opal, chemically machined Fotoform® and Fotoceram®, and TiO2-nucleated Pyroceram™ products including missile nosecones and oven-proof cookware. He received a basic patent on glass-ceramics which was contested and affirmed in court.Don was able to demonstrate a clear photochromic glass that showed reversible darkening for thousands of cycles. This material became a fixture in the ophthalmic industry. He went on to invent a full-color polychromatic glass capable of yielding a permanent patterned and monolithic stained glass.In his life outside science, Don chaired an interfaith group that founded a home for the elderly in Corning. He was also a wilderness enthusiast, surviving a plane crash in the Arctic and two boat capsizings. Even In his later years, he continued fishing off the coast of Florida and on Lake Ontario, and went solo on a trip to the Patagonian Andes.

  16. Birds of a Feather Don't Always Flock Together : User Problems in ...

    African Journals Online (AJOL)

    Birds of a Feather Don't Always Flock Together : User Problems in Identifying ... for Advanced Learners and Oxford Advanced Learner's Dictionary) revealed a lack ... This paper is based on 14 of these phrasemes, which appear in one or more of ... Five strategies are presented to help learners with their dictionary searches.

  17. Il don giovanni tenorio di carlo goldoni. Alle origini di un mito moderno

    African Journals Online (AJOL)

    By transforming the protagonist's religious impiety into sexual incontinence, Goldoni draws a link between Molière's drama (1665) and the version set to music by Mozart in 1787. An analysis of the text with a focus on the reception and adaptation by Goldoni of the early plays reveals the centrality of his Don Giovanni in the ...

  18. "Boys Don't Cry," a Movie Review: Implications for Counseling Persons Who Are Transgendered

    Science.gov (United States)

    Aguilar, Jinnelle Veronique

    2010-01-01

    People who fall under the umbrella of transgender belong to one of the most marginalized groups within society. Many who do not pass within the gender binary categories imposed by social norms experience discrimination and marginalization. In this article, the author discusses the film "Boys Don't Cry" and introduces the reader to the varieties of…

  19. The E-learning Cabaret: do's and don'ts in E-Learning Design

    NARCIS (Netherlands)

    Westera, Wim

    2009-01-01

    Westera, W. (2006). The E-Learning Cabaret: do's and don'ts in E-Learning Design. Book of Abstracts, 12th International Conference on Technology Supported Learning & Teaching, Online Educa Berlin (pp. 169-171). November, 29-December, 1, 2006, Berlin, Germany: ICWE-GmbH.

  20. What We Don't Understand, We Explain to Each Other

    Science.gov (United States)

    Pines, David

    2015-01-01

    "What we don't understand, we explain to each other" was Robert Oppenheimer's 1948 description of theoretical physics as a profession. Because the phrase connects research, teaching, and learning, it seemed the right approach for the talk I gave to the AAPT [American Association of Physics Teachers] on receiving the 2013 J.D. Jackson…

  1. Transient identification system with noising data and 'don't know' response

    International Nuclear Information System (INIS)

    Mol, Antonio C. de A.; Martinez, Aquilino S.; Schirru, Roberto

    2002-01-01

    In the last years, many different approaches based on neural network (NN) has been proposed for transient identification in nuclear power plants (NPP). Some of them focus the dynamic identification using recurrent neural networks however, they are not able to deal with unrecognized transients. Other kind of solution uses competitive learning in order to allow the 'don't know' response. In this case dynamic, dynamic features are not well represented. This work presents a new approach for neural network based transient identification which allows either dynamic identification and 'don't know'response. Such approach uses two multilayer neural networks trained with backpropagation algorithm. The first one is responsible for the dynamic identification. This NN uses, a short set (in a movable time window) of recent measurements of each variable avoiding the necessity of using starting events. The other one is used to validate the instantaneous identification (from the first net) through the validation of each variable. This net is responsible for allowing the system to provide 'don't know' response. In order to validate the method a NPP transient identification problem comprising 15 postulated accidents, simulated for a pressurized water reactor, was proposed in the validation process it has been considered noising data in other to evaluate the method robustness. Obtained results reveal the ability of the method in dealing with both dynamic identification of transients and correct 'don't know' response. In order to validate the method, a NPP transient identification problem comprising 15 postulated accidents simulated for a pressurized water reactor, was proposed in the validation process it has been considered noising data in order to evaluate the method robustness. Obtained results reveal the ability of the method in dealing with both dynamic identification of transients and correct 'don't know' response. (author)

  2. L’utilité de la théorie du don The utility of gift theory Utilidad de la teoría del don

    Directory of Open Access Journals (Sweden)

    Norbert Alter

    2012-12-01

    Full Text Available Norbert Alter explique l’utilité et l’actualité de la théorie de Marcel Mauss pour penser la coopération en entreprise et l’engagement au travail. Il revient sur ses qualités heuristiques et sa portée critique nécessaires à mobiliser pour donner des clefs de compréhension et d’action au monde du travail. À cette contribution répond celle d’Alain Caillé, « Le paradigme du don face aux nouvelles réalités du monde du travail. Quelques remarques »Norbert Alter explains here the utility and topicality of Marcel Mauss’ theory in an analysis touching both on cooperation within a business structure and on people’s commitment to work. He reviews the heuristic qualities and critical scope that must be mobilised to create ways of understanding and acting within the work world. Alain Caillé responds to this contribution with his own article entitled, “ The gift paradigm facing new realities in the work world. Comments” (Le paradigme du don face aux nouvelles réalités du monde du travail. Quelques remarques.Norbert Alter explica la utilidad y la actualidad de la teoría de Marcel Mauss para pensar la cooperación en la empresa y el compromiso en el trabajo. Desde una nueva perspectiva, aborda las cualidades heurísticas de esa teoría y su alcance crítico, que es necesario movilizar para contar con claves de comprensión y de acción en el mundo laboral. A su contribución, Alain Caillé responde con el artículo “El paradigma del don frente a las nuevas realidades del mundo laboral. Algunas observaciones”.

  3. Don't Let Gun Sports Backfire on You: Use Ear Protection and Hang onto Your Hearing

    Science.gov (United States)

    ... Inside NIDCD Newsletter » Spring 2006 Don't Let Gun Sports Backfire on You: Use Ear Protection and ... in the skeet event, would never fire a gun without them. Likewise, Dave Henderson, a nationally recognized ...

  4. “I don't use a condom (with my regular partner) because I know that I ...

    African Journals Online (AJOL)

    I don't use a condom (with my regular partner) because I know that I'm faithful, but with everyone else I do”: The cultural and socioeconomic determinants of sexual partner concurrency in young South Africans.

  5. Deoxynivalenol (DON Contamination of Feed and Grinding Fineness: Are There Interactive Implications on Stomach Integrity and Health of Piglets?

    Directory of Open Access Journals (Sweden)

    Sven Dänicke

    2017-01-01

    Full Text Available The common feed contaminant deoxynivalenol (DON was reported to influence the morphology of the pars nonglandularis (PN of porcine stomach. Moreover, finely ground feed is known to trigger the development of ulcers and other pathologies of PN while coarsely ground feed protects from such lesions. The interactions between grinding fineness and DON contamination of feed were not examined so far. Therefore, both finely and coarsely ground feeds were tested either in the absence or presence of a DON contaminated wheat on growth performance and health of rearing piglets, including stomach integrity. DON contamination significantly reduced feed intake and serum albumin concentration with this effect being more pronounced after feeding the coarsely ground feed. Albeit at a higher level, albumin concentration was also reduced after feeding the finely ground and uncontaminated feed. Finely ground and DON-contaminated feed caused a significantly more pronounced lymphoplasmacytic infiltration both of PN and pars glandularis, partly paralleled by lymph follicle formation and detritus filled foveolae and tubes suggesting a local immune response probably triggered by epithelial lesions. It is concluded that DON contamination of feed exacerbates the adverse effects of finely ground feed on stomach mucosal integrity.

  6. Deoxynivalenol (DON) Contamination of Feed and Grinding Fineness: Are There Interactive Implications on Stomach Integrity and Health of Piglets?

    Science.gov (United States)

    Dänicke, Sven; Beineke, Andreas; Berk, Andreas; Kersten, Susanne

    2017-01-01

    The common feed contaminant deoxynivalenol (DON) was reported to influence the morphology of the pars nonglandularis (PN) of porcine stomach. Moreover, finely ground feed is known to trigger the development of ulcers and other pathologies of PN while coarsely ground feed protects from such lesions. The interactions between grinding fineness and DON contamination of feed were not examined so far. Therefore, both finely and coarsely ground feeds were tested either in the absence or presence of a DON contaminated wheat on growth performance and health of rearing piglets, including stomach integrity. DON contamination significantly reduced feed intake and serum albumin concentration with this effect being more pronounced after feeding the coarsely ground feed. Albeit at a higher level, albumin concentration was also reduced after feeding the finely ground and uncontaminated feed. Finely ground and DON-contaminated feed caused a significantly more pronounced lymphoplasmacytic infiltration both of PN and pars glandularis, partly paralleled by lymph follicle formation and detritus filled foveolae and tubes suggesting a local immune response probably triggered by epithelial lesions. It is concluded that DON contamination of feed exacerbates the adverse effects of finely ground feed on stomach mucosal integrity. PMID:28045426

  7. The first theatrical adaptations of the Don Quixote and the beginning of Cervantes

    Directory of Open Access Journals (Sweden)

    Carmen Rivero Iglesias

    2012-12-01

    Full Text Available The present study analyzes the first appearances of Don Quixote on German stages. The goal is to illustrate how these theatrical performances determine the reception of Cervantes’ work in 17th century Germany. The first performances in Heidelberg (1613 and Dessau (1614 display an interpretation of Don Quixote, which intensifies the grotesque dimension of Cervantes’ original. Its satire is transformed into a satire of Spain in a context determined by political and religious animosity between Catholics and Protestants. The first German translation inherited this conception of Cervantes’ work. This conception would acquire new shades until middle of the 18th century, when the alteration of historical coordinates and the rise of individuality and genius thoroughly transformed its interpretation.

  8. Operatic films: a comparative study of Don Giovanni by Joseph Losey and Juan by Kasper Holten

    Directory of Open Access Journals (Sweden)

    Isabel VILLANUEVA BENITO

    2017-12-01

    Full Text Available From an artistic point of view, the adaptation of an opera to the cinema, traditionally has been considered a complex and controversial process. Don Giovanni, of W.A. Mozart is one of the operas that more audiovisual versions has generated during the centuries XX and XXI, although very few films have finally been taken to the screen. This paper is focused on comparing the audiovisual versions Don Giovanni, by Joseph Losey (1979, and Juan by Kasper Holten (2010. Through a quantitative and qualitative methodology based on content analysis, this research reflects on the degree of intervention exercised by the language and audiovisual format used in the process of reinterpretation of the pre-existing operatic text.

  9. ["Is it an animal inside? "Melanie Klein's unpublished Don Juan Paper (1939)].

    Science.gov (United States)

    Frank, Claudia

    2008-01-01

    Klein had been asked to contribute an article to the birthday number of the International Journal for Jones. The author outlines how she hurriedly wrote a text about Don Juan which, however, was rejected by the editor. Essential parts of it are presented in German translation. The manuscript is discussed in the context of Klein's published work as well as of the relevant contemporary literature. In Klein's view, Don Juan's genitality is determined by oral impulses and fears. By his manic acting out he attempts to ward off a depressive break-down. The paper ends with some reflections about why Klein--ontrary to her intention--failed to revise her manuscript for later publication.

  10. Don Quijote, doña Rodríguez y los duques

    Directory of Open Access Journals (Sweden)

    Stanislav Zimic

    1997-12-01

    Full Text Available Al llegar Don Quijote al palacio de los duques y "viéndose tratar del mesmo modo que él había leído se trataban Ios tales caballeros en Ios pasados siglos ... , aquél fue el primer día que de todo en todo conoció y creyó ser caballero andante verdadero y no fantastíco" (1378. Comprensiblemente, esta afirmacion ha causado gran perplejidad entre los lectores de todas las épocas: "Luego, antes ¿no lo había creído?" . La cuestión se complica mucho más, poco después de estos eufóricos momentos, al confesar Don Quijote a la duquesa: "Dios sabe si hay Dulcinea o no en el mundo, o si es fantástica ono es fantástica ...

  11. Detection of calmodulin binding protein at 170 KDA in BALB, AKR, DON and chicken granulosa cells

    International Nuclear Information System (INIS)

    Selinfreund, R.; Lin, P.H.; Marrone, B.; Wharton, W.

    1987-01-01

    Calmodulin (CAM) has been shown to bind to the epidermal growth factor (EGF) receptor (170 kDa) and is phosphorylated in a EGF dependent manner in the A431 human epidermoid carcinoma cells. In the present study, they report 125 I-CAM binding to a 170 kDa protein detected in cell membrane vesicles of Balb/3T3, AKR, DON and chicken granulosa cells. Purified plasma membranes from these cells were resolved via electrophoresis (without heat denaturation) and electroblotted onto nictrocellulose paper. Upon hybridizing against 125 I-CAM, a distinct autoradiographic band occurred at 170 kDa for all the cells lines under study. The binding of CAM is specific and can be displaced with the addition of excess unlabeled CAM. The result suggest that 125 I-CAM may bind to the 170 kDa EGF receptor in BALB, AKR, DON and chicken granulosa cells

  12. Bauhinia Pottsii G. Don Var Pottsii, Koleksi Dari Kalimantan Yang Ditemukan Kembali

    OpenAIRE

    Astuti, Inggit Puji; Magandhi, Mahat; Suratman, Maman; Maulida, Risa

    2012-01-01

    Bauhinia is one of the largest genus in Caesalpiniaceae family and distributed in all tropical area. One among 300 species of Bauhinia is Bauhinia pottsii G. Don. This species is distributed from Southern Myanmar, Thailand, Cambodia, Malay Peninsular, Borneo, Sumatra, Jawa, Bali and Lesser Sunda islands. It was recorded that one specimen was originated from East Kalimantan and collected in 1925. During exploration in Kampung Temula, Kecamatan Nyuatan, Kabupaten Kutai Barat, East Kalimantan,...

  13. Mujeres españolas de la conquista en don Joan de Castellanos (I

    Directory of Open Access Journals (Sweden)

    Mario Germán Romero

    1962-10-01

    Full Text Available La participación de la mujer española en la conquista de América es un tema que apenas comienza a ser tratado con la profundidad que merece. A principios del siglo don Cesáreo Fernández Duro publicó una breve disertación sobre ' 'La mujer española en Indias".

  14. Punctuation in the text of the Golden Age and in Don Quijote

    Directory of Open Access Journals (Sweden)

    Ignacio Arellano

    2010-12-01

    Full Text Available This article examines the punctuation in Golden Age texts, in particular in Don Quixote. The author analyzes the discrepancies between theory and practice of the printers, the features of the punctuation in manuscripts, and the absence of a general system, due in part to the absence of a unique and precise system in Spanish. The article provides numerous examples of Golden Age text and of the Quixote.

  15. Department of the Navy (DON) Additive Manufacturing (AM) Implementation Plan V2.0 (2017)

    Science.gov (United States)

    2017-05-04

    aligned to advance AM of explosives, propellants, pyrotechnics and structures.  Makerspaces deployed throughout the warfighter and civilian communities...to conduct broad AM familiarization training and STEM activities 2. Introduce new makerspaces into DON to expand access and education of AM...technologies 3. Ensure makerspaces become a vital part of workforce training by developing communication plan to inform leadership of current and future

  16. Hedyotis pinifolia Wall. ex G. Don (Rubiaceae, a New Record to the Flora of Taiwan

    Directory of Open Access Journals (Sweden)

    Shih-Huei Chen

    2010-03-01

    Full Text Available Hedyotis pinifolia Wall. ex G. Don, a species of Rubiaceae, was found recently in Taiwan. It represents a new record for the flora of Taiwan, and a range extension of the species to the northeast. The present study provides the species description, illustrations, and SEM micrographs of seeds and pollen grains. Furthermore, a comparison of diagnostic characters between this species and a related species, H. tenelliflora Bl. is made.

  17. Detsibill : Meie Mees kui ANTI. White Label : Don Erikson. Kuula / DJ Pickney Tiger

    Index Scriptorium Estoniae

    DJ Pickney Tiger, pseud., 1970-

    2006-01-01

    Heliplaatidest: Don Erikson "Israel Mix", Congotronics 2 "Buzz'n'rumble from the urb'n'jungle", Critikal "Chapter One ehk Teine maitse", Nirvana "Silver, The best of the Box", Singer Vinger "Eesti Kullafond", Bullet Train To Vegas "We Put Scissors Where Our Mouths Are", Ludachris "Disturbing tha peace", "Soul Satisfaction 5", The Kurt Webber's Pink Band "Café Regatt", Patrizio Buanne "The Italian", Eminem "Curtain Call"

  18. Los centenarios: El bibliotecario don Manuel del Socorro Rodríguez

    Directory of Open Access Journals (Sweden)

    Boletín Cultural y Bibliográfico Banco de la República

    1958-04-01

    Full Text Available Se cumplió en este mes de abril el segundo centenario del nacimiento de don Manuel del Socorro Rodríguez. Con tal motivo, su memoria fue honrada con la celebración del Día del Bibliotecario, una magnífica iniciativa que, como dijo alguien, debe convertirse en una tradición cultural de Colombia.

  19. Don E. Detmer and the American Medical Informatics Association: An Appreciation

    Science.gov (United States)

    Shortliffe, Edward H.; Bates, David W.; Bloomrosen, Meryl; Greenwood, Karen; Safran, Charles; Steen, Elaine B.; Tang, Paul C.; Williamson, Jeffrey J.

    2009-01-01

    Don E. Detmer has served as President and Chief Executive Officer of the American Medical Informatics Association (AMIA) for the past five years, helping to set a course for the organization and demonstrating remarkable leadership as AMIA has evolved into a vibrant and influential professional association. On the occasion of Dr. Detmer's retirement, we fondly reflect on his professional life and his many contributions to biomedical informatics and, more generally, to health care in the U.S. and globally. PMID:19574463

  20. Application of gamma radiation to the nodes detection in Pinus Radiata (D.Don) wood pieces

    International Nuclear Information System (INIS)

    Morales, J.R.; Dinator, Maria I; Karsulovic C, Jose T.; Leon G, Adolfo

    1996-01-01

    Attenuation of 59.5 KeV photons provided by an Am-241 source, has been used to detect knots in lumber pieces from Pinus Radiata (D.Don). It is shown that the linear attenuation coefficient is a sensitive parameter to detect singularities in the structure of this material. The scanning of the piece provides profiles which define the position and extension of the singularity. (author)

  1. Inflatable Emergency Equipment I: Evaluation of Individual Inflatable Aviation Life Preserver Donning Tests

    Science.gov (United States)

    2014-12-01

    have to do so in the water. Shortly thereafter, the Survival Research Unit at CAMI devel- oped a prototype life preserver, with a primary goal of...calculate the various donning function times, as defined below. These were entered into IBM SPSS ® version 21 for statistical analysis. “TSO Test Time...inflation tubes, manual inflation triggering devices with pull tabs and CO2 cartridges, and designed to be reversible. The experimental life preserver

  2. Reproduction et Diversité Génétique chez Parkia biglobosa (Jacq.) G. Don

    NARCIS (Netherlands)

    Sina, S.

    2006-01-01

    Parkiabiglobosa(Jacq.)G.Don, African

  3. "Don't know" responses to risk perception measures: implications for underserved populations.

    Science.gov (United States)

    Waters, Erika A; Hay, Jennifer L; Orom, Heather; Kiviniemi, Marc T; Drake, Bettina F

    2013-02-01

    Risk perceptions are legitimate targets for behavioral interventions because they can motivate medical decisions and health behaviors. However, some survey respondents may not know (or may not indicate) their risk perceptions. The scope of "don't know" (DK) responding is unknown. Examine the prevalence and correlates of responding DK to items assessing perceived risk of colorectal cancer. Two nationally representative, population-based, cross-sectional surveys (2005 National Health Interview Survey [NHIS]; 2005 Health Information National Trends Survey [HINTS]), and one primary care clinic-based survey comprised of individuals from low-income communities. Analyses included 31,202 (NHIS), 1,937 (HINTS), and 769 (clinic) individuals. Five items assessed perceived risk of colorectal cancer. Four of the items differed in format and/or response scale: comparative risk (NHIS, HINTS); absolute risk (HINTS, clinic), and "likelihood" and "chance" response scales (clinic). Only the clinic-based survey included an explicit DK response option. "Don't know" responding was 6.9% (NHIS), 7.5% (HINTS-comparative), and 8.7% (HINTS-absolute). "Don't know" responding was 49.1% and 69.3% for the "chance" and "likely" response options (clinic). Correlates of DK responding were characteristics generally associated with disparities (e.g., low education), but the pattern of results varied among samples, question formats, and response scales. The surveys were developed independently and employed different methodologies and items. Consequently, the results were not directly comparable. There may be multiple explanations for differences in the magnitude and characteristics of DK responding. "Don't know" responding is more prevalent in populations affected by health disparities. Either not assessing or not analyzing DK responses could further disenfranchise these populations and negatively affect the validity of research and the efficacy of interventions seeking to eliminate health disparities.

  4. La parodia como marco estructural en Don Quijote y Los viajes de Gulliver

    Directory of Open Access Journals (Sweden)

    Alfonso Muñoz Corcuera

    2016-07-01

    Full Text Available Los viajes de Gulliver, de Jonathan Swift, es una de las obras más conocidas de la literatura universal. Sin embargo, su recepción actual, al menos en España, se produce sobre todo por medio de adaptaciones en las que no se puede apreciar el calado de la obra literaria original. En este estudio se pretende profundizar en el análisis de Los viajes de Gulliver a través de una comparación con Don Quijote, enfocándose en los recursos paródicos: mientras Don Quijote parodia los libros de caballerías, Los viajes de Gulliver parodia los libros de viajes. El principal objetivo de esta comparación no será tanto demostrar una influencia de la obra de Cervantes sobre la de Swift, sino, más bien, iluminar algunos aspectos de Los viajes de Gulliver. Gulliver´s Travels, of Jonathan Swift, is one of the most well-known works in world literature. However, its actual reception, at least in Spain, it´s produced mostly through adaptations in which it´s impossible to appreciate the profundity of the original literary work. In this article, I intend to dig deeply into the analysis of Gulliver´s Travels through a comparison with Don Quixote, focusing on the parodic resources: while Don Quixote parodies the books of chivalry, Gulliver´s Travels parodies travel books. The main goal of this comparison will not be to prove some influence of Cervantes´ work in Swift´s work, but to illuminate some aspects of Gulliver´s Travels.

  5. Reflections on Don Juan and on the utility of the unhappy love affair.

    Science.gov (United States)

    Bergel, Ernest

    2011-12-01

    Based on an unusual clinical experience of a teenage boy in child psychotherapy, two conclusions are proposed: (1) that the extremely unhappy, early love affairs that occur in most men's lives serve a valuable function in helping them separate from their mothers sufficiently to be able to realistically relate to appropriate marriage partners, and (2) that some Don Juans start new relationships in order to break them off, rather than the reverse.

  6. The voice of Cervantes «creator» in Don Quixote

    Directory of Open Access Journals (Sweden)

    Florencio Sevilla Arroyo

    2010-12-01

    Full Text Available The aim of this paper is identifying the genuine voice of the Cervantes creator in the multiple choir of fictitious intermediaries involved in the authorship and the story of Don Quijote (reporter, editor, translator, Cide Hamete, supernarrator, readers, etc. trying, at the same time, to gauging the sense and the scope of their interventions. It happens that Miguel de Cervantes keeps to himself a novelistic role radically different depending on whether it is about the «story of story» or the «story itself»: refering to the first one, the author is out of the cast, delegating the reconstruction of Don Quixote’s legend in multiple fictional masks always comically manipulated; on the other hand, when it is the turn to the novelistic design of the chivalrous adventures of Don Quixote and Sancho, the voice of Cervantes creator comes to the forefront in order to take on, —as the «final author»— all narrative responsibility with absolute omniscience and solemnity. The resulting Quijote can only be explained from the intersection of both attitudes: the risible story of the most solemn/serious and magnificent novelistic bet never tried out..

  7. The Rhetoric of Madness in Kathy Acker’s Don Quixote

    Directory of Open Access Journals (Sweden)

    Claudia Cao

    2017-07-01

    Full Text Available This essay examines the rhetorical experimentation of Don Quixote by Kathy Acker, starting from a theoretical concept central in the author’s thought: her search for a “language of the body”. A brief introduction to Kathy Acker’s plagiaristic poetics frames her narrative strategies between postmodern rewriting and pastiche. It shows the way in which her Don Quixote transposes the representative scheme of the chivalric quest into the contemporary value system with the aim of questioning Cervantes’ text as one of the canonical works of the Western literary tradition. The following section deepens three focal concepts of Acker’s theoretical works – body, madness, and norm – illuminating the connections between her rhetorical experimentation and the works by Luce Irigaray and Judith Butler. Finally, the paper will demonstrate how these concepts in Acker's rewriting of Don Quixote are strictly related to paradox, which she uses in order to actualize a “language of the body”: in the passage from the former novel to the postmodern work, madness has become the device which, from the semantic level to the rhetorical one, expresses Acker’s idea of language of the body, as an alternative and in contrast to the canonical language of the logos.

  8. A neural model for transient identification in dynamic processes with 'don't know' response

    International Nuclear Information System (INIS)

    Mol, Antonio C. de A.; Martinez, Aquilino S.; Schirru, Roberto

    2003-01-01

    This work presents an approach for neural network based transient identification which allows either dynamic identification or a 'don't know' response. The approach uses two 'jump' multilayer neural networks (NN) trained with the backpropagation algorithm. The 'jump' network is used because it is useful to dealing with very complex patterns, which is the case of the space of the state variables during some abnormal events. The first one is responsible for the dynamic identification. This NN uses, as input, a short set (in a moving time window) of recent measurements of each variable avoiding the necessity of using starting events. The other one is used to validate the instantaneous identification (from the first net) through the validation of each variable. This net is responsible for allowing the system to provide a 'don't know' response. In order to validate the method, a Nuclear Power Plant (NPP) transient identification problem comprising 15 postulated accidents, simulated for a pressurized water reactor (PWR), was proposed in the validation process it has been considered noisy data in order to evaluate the method robustness. Obtained results reveal the ability of the method in dealing with both dynamic identification of transients and correct 'don't know' response. Another important point studied in this work is that the system has shown to be independent of a trigger signal which indicates the beginning of the transient, thus making it robust in relation to this limitation

  9. Change and persistence in land surface phenologies of the Don and Dnieper river basins

    Energy Technology Data Exchange (ETDEWEB)

    Kovalskyy, V; Henebry, G M, E-mail: geoffrey.henebry@sdstate.ed [Geographic Information Science Center of Excellence (GIScCE), South Dakota State University, 1021 Medary Avenue, Wecota Hall 506B, Brookings, SD 57007-3510 (United States)

    2009-10-15

    The formal collapse of the Soviet Union at the end of 1991 produced major socio-economic and institutional dislocations across the agricultural sector. The picture of broad scale patterns produced by these transformations continues to be discovered. We examine here the patterns of land surface phenology (LSP) within two key river basins-Don and Dnieper-using AVHRR (Advanced Very High Resolution Radiometer) data from 1982 to 2000 and MODIS (Moderate Resolution Imaging Spectroradiometer) data from 2001 to 2007. We report on the temporal persistence and change of LSPs as summarized by seasonal integration of NDVI (normalized difference vegetation index) time series using accumulated growing degree-days (GDDI NDVI). Three land cover super-classes-forest lands, agricultural lands, and shrub lands-constitute 96% of the land area within the basins. All three in both basins exhibit unidirectional increases in AVHRR GDDI NDVI between the Soviet and post-Soviet epochs. During the MODIS era (2001-2007), different socio-economic trajectories in Ukraine and Russia appear to have led to divergences in the LSPs of the agricultural lands in the two basins. Interannual variation in the shrub lands of the Don river basin has increased since 2000. This is due in part to the better signal-to-noise ratio of the MODIS sensor, but may also be due to a regional drought affecting the Don basin more than the Dnieper basin.

  10. Effects of temperature and time on deoxynivalenol (DON and zearalenone (ZON content in corn

    Directory of Open Access Journals (Sweden)

    Jauković Marko

    2014-01-01

    Full Text Available Fumonisins are Fusarium mycotoxins that occur in corn and corn-based foods and they have been implicated in several animal and human diseases. Their effect on human health is unclear, however, fumonisins are considered to be risk factors for cancer. Baking, frying, and extrusion cooking of corn at high temperatures (190°C reduce fumonisin concentrations in foods, with the amount of reduction achieved depending on cooking time, temperature, recipe, and other factors. The aim of this work was to evaluate the effectiveness of temperature (200 and 220 °C and time (15 and 20 min on the detoxification of corn flour deliberately contaminated with DON and ZON. After processing at 200°C for 15 min, an average of 12% and after 20 min an average of 15% of DON was lost. At 200°C ZON content was reduced by 22% (after 15 min and by 27% (after 20 min. Higher temperature (220°C did not significantly affect further reduction of DON or ZON content. The process was only partially effective in both cases. [Projekat Ministarstva nauke Republike Srbije, br. TR-31023 i br. TR-31053

  11. El don: entre las prácticas intersticiales y el solidarismo

    Directory of Open Access Journals (Sweden)

    ADRIÁN SCRIBANO

    2014-08-01

    Full Text Available El presente trabajo busca hacer evidente al solidarismo como la "pérdida del don", conforme expuesto por Mauss, en el contexto de la situación colonial, de los procesos de expansión capitalista en la actualidad. Como objeto de análisis y mediación hermenéutica, hemos seleccionado a la Responsabilidad Social Empresarial (RSE como una forma del solidarismo cuyas prácticas llevan a un conjunto de situaciones que pueden describirse como pornográficas. Para lograr el objetivo explicitado, hemos seguido la siguiente estrategia argumentativa: a se sintetizan algunas pocas coordenadas de carácter teóricos que permitan entender la centralidad del don y se explicita nuestra idea de solidarismo, b se realiza un triple análisis: de la conceptualización de la RSE y de las experiencias de RSE de algunas corporaciones internacionales en Argentina; y c se exponen nuestras ideas sobre prácticas intersticiales en tanto hiatos que quiebran a la economía política de la moral como una totalidad que demanda la "pérdida" de todo tipo de don.

  12. Hubungan antara Aktivitas Fisik Terhadap Memori Kerja Murid SMA Don Bosco III Bekasi

    Directory of Open Access Journals (Sweden)

    Michelle Clarissa Junaidi

    2017-03-01

    Full Text Available Latar belakang. Memori kerja merupakan bagian dari memori jangka pendek yang berperan penting dalam membantu proses pembelajaran dan dipengaruhi oleh aktivitas fisik, memori kerja yang rendah akan menimbulkan kesulitan untuk menerima informasi baru serta penurunan prestasi belajar. Tujuan. Mengetahui pengaruh aktivitas fisik terhadap kapasitas memori kerja murid SMA Don Bosco III. Metode. Penelitian metode analitik dengan pendekatan potong lintang pada 113 murid SMA Don Bosco III, Bekasi, pada 18 – 20 Juli 2016. Penelitian dilakukan dengan menggunakan kuesioner demografi, kuesioner skrining gangguan mental dan penyakit kronis, Physical Acitivity Questionnaire of Adolescent (PAQ-A dan Operation Span (O-SPAN. Analisis data dengan univariat dan bivariat menggunakan uji korelasi Spearman. Hasil. Terdapat 113 murid SMA Don Bosco III dengan kisaran usia 14 – 17 tahun, usia terbanyak 15 tahun (47.8%, laki-laki 61,1%, murid kelas X 44.2%. Mayoritas responden memiliki aktivitas fisik “kurang baik” dan rerata memori kerja 6,16. Analisis Spearman menunjukkan terdapat hubungan bermakna (p<0,05 antara aktivitas fisik terhadap memori kerja dengan korelasi positif lemah (r=0,384. Kesimpulan. Terdapat korelasi positif antara aktivitas fisik dan memori kerja, aktivitas fisik yang semakin tinggi cenderung akan meningkatkan memori kerja.

  13. Change and persistence in land surface phenologies of the Don and Dnieper river basins

    International Nuclear Information System (INIS)

    Kovalskyy, V; Henebry, G M

    2009-01-01

    The formal collapse of the Soviet Union at the end of 1991 produced major socio-economic and institutional dislocations across the agricultural sector. The picture of broad scale patterns produced by these transformations continues to be discovered. We examine here the patterns of land surface phenology (LSP) within two key river basins-Don and Dnieper-using AVHRR (Advanced Very High Resolution Radiometer) data from 1982 to 2000 and MODIS (Moderate Resolution Imaging Spectroradiometer) data from 2001 to 2007. We report on the temporal persistence and change of LSPs as summarized by seasonal integration of NDVI (normalized difference vegetation index) time series using accumulated growing degree-days (GDDI NDVI). Three land cover super-classes-forest lands, agricultural lands, and shrub lands-constitute 96% of the land area within the basins. All three in both basins exhibit unidirectional increases in AVHRR GDDI NDVI between the Soviet and post-Soviet epochs. During the MODIS era (2001-2007), different socio-economic trajectories in Ukraine and Russia appear to have led to divergences in the LSPs of the agricultural lands in the two basins. Interannual variation in the shrub lands of the Don river basin has increased since 2000. This is due in part to the better signal-to-noise ratio of the MODIS sensor, but may also be due to a regional drought affecting the Don basin more than the Dnieper basin.

  14. The silent Don Juan. The concepts of love and art in the works of Max Frisch

    Directory of Open Access Journals (Sweden)

    Špela Virant

    2012-07-01

    Full Text Available In the novel Stiller and in the play Don Juan, both published in the early 1950s, Frisch already focuses on the problem of identity as one of his major themes, but it is not yet situated in a political context as, for example, in the play Andorra. In these works, the identity-problem is situated in the domain of intimate relationships and artistic creativity, offering the possibility to discuss Frisch’s concepts of art and love, which unfold through Frisch’s treatment of the traditional literary figure of Don Juan and his hubris. Frisch’s Stiller and Don Juan do not believe in God; but their frame of mind stays the same, while the position of God and his attributes are assigned to love, art and geometry. Although both literary figures in the course of events realize that this substitution is a mistake, they are unable to alter their concepts of love and art. Instead of altering the concepts, they rather resign in silence, while Max Frisch continues to search for alternatives in reflecting on the process of fictionalization and in developing innovative narrative and dramatic structures.

  15. de "subirnos al tiempo". La economía del "don"

    Directory of Open Access Journals (Sweden)

    Raúl García Durán

    2007-01-01

    Full Text Available Este trabajo resume las ideas contenidas en el libro -aún inédito- De la miseria de la economía a la plenitud de la fraternidad; o la economía del "don" como alternativa al capitalismo y la economía de mercado. En él se plantean alternativas radicales al capitalismo; particularmente, se ubica al "don" como camino de pensamiento y acción. Se documentan las proposiciones teóricas y aportes de la economía política, la antropología, la historia, para construir la manera en que el don podría contribuir a una reorganización social basada en nuevos-viejos principios. Se interrogan diversas experiencias histórico-antropológicas y su prefiguración actual en un nuevo modelo ético-político-ecológico que abarca las dimensiones local y global.

  16. Information Technology Portfolio Management and the Real Options Method (ROM): Managing the Risks of IT Investments in the Department of the Navy (DON)

    National Research Council Canada - National Science Library

    Davis, Jeffery

    2003-01-01

    .... This research draws upon ITPM implementation strategies currently employed by the DON and provides recommendations for managing the inherent risk in IT investments, specifically the application...

  17. Cervantes, Lizardi, and the Literary Construction of The Mexican Rogue in Don Catrín de la fachenda

    Directory of Open Access Journals (Sweden)

    Vilches Patricia

    2017-12-01

    Full Text Available This study explores the socio-economic legacies and critique of nation-building found in the work of Jose Joaquin Fernandez de Lizardi (1776-1827. In the nineteenth century, the Latin American elite struggled to disassociate itself from a suffocating colonial machine; they sought their own identity, and writing became a way to express their frustration. As in other parts of Latin America, Mexican intellectuals protested fossilisation via Cervantes’s Don Quijote. Using the Spanish author’s text as a blueprint, Lizardi’s Don Catrín de la fachenda depicted a turbulent society that was in the process of abandoning a decaying colonial order. Don Quijote’s characters engaged in power struggles and were involved in a variety of forms of social antagonism. Lizardi juxtaposed and superimposed these on an American geographical and socio-economic space where there was much dissension around the nation’s direction. The social and economic rules of Mexico (and Latin America today can be said to be already present in the social exchanges in Don Catrín. It was in this context that Don Quijote was “Mexicanised” by Lizardi and thereby made to participate in local reflections on liberty, patriotism, capitalism, and citizenship. Cervantes’s text thus took on a socio-political meaning in the narrative of Latin America’s past and present.

  18. De la risa a carcajadas al mal ejemplo quijotesco en la novela del XVIII. Don Quijote de la Manchuela

    Directory of Open Access Journals (Sweden)

    Agapita Jurado Santos

    2013-03-01

    Full Text Available Don Quixote rapidly became a huge success. It was translated into several languages and reworked into genres with a festive and theatrical nature. In Spain, during the seventeenth century, its comic side was exploited, which provoked liberating laughter that, in France, led to its association with the satire genre. In the eighteenth century, the novel was considered a minor genre, of no educational value. The century began with a fierce controversy over the meaning of Cervantes’ work, since according to Rapin, some readers would have seen a mockery of the Spanish nobility in the insane gentleman. However, during the eighteenth century the first steps were taken to reappraise Don Quixote due to its acceptance as a classic by the Spanish Royal Academy in 1780. The Academy considered Don Quixote a mocking and didactic hero, a bad example to be avoided. Yet, the work was an important step in the construction of a new genre, the novel. Don Quijote de la Manchuela, by Donato de Arenzana (1767, reflects an attentive reading of Cervantes’ Don Quixote, and special attention to the neoclassical cannon. Therefore it can provide useful information about writers’ interests, in the preromantic eighteenth century.

  19. Transcriptome analysis of the human T lymphocyte cell line Jurkat and human peripheral blood mononuclear cells exposed to deoxynivalenol (DON): New mechanistic insights

    Energy Technology Data Exchange (ETDEWEB)

    Katika, Madhumohan R. [RIKILT-Institute of Food Safety, Wageningen University and Research Centre, Wageningen (Netherlands); Department of Health Risk Analysis and Toxicology, Maastricht University (Netherlands); Netherlands Toxicogenomics Centre (Netherlands); Hendriksen, Peter J.M. [RIKILT-Institute of Food Safety, Wageningen University and Research Centre, Wageningen (Netherlands); Netherlands Toxicogenomics Centre (Netherlands); Shao, Jia [RIKILT-Institute of Food Safety, Wageningen University and Research Centre, Wageningen (Netherlands); Department of Health Risk Analysis and Toxicology, Maastricht University (Netherlands); Netherlands Toxicogenomics Centre (Netherlands); Loveren, Henk van [Department of Health Risk Analysis and Toxicology, Maastricht University (Netherlands); National Institute for Public Health and the Environment (RIVM), Bilthoven (Netherlands); Netherlands Toxicogenomics Centre (Netherlands); Peijnenburg, Ad, E-mail: ad.peijnenburg@wur.nl [RIKILT-Institute of Food Safety, Wageningen University and Research Centre, Wageningen (Netherlands); Netherlands Toxicogenomics Centre (Netherlands)

    2012-10-01

    Deoxynivalenol (DON) or vomitoxin is a commonly encountered type-B trichothecene mycotoxin, produced by Fusarium species predominantly found in cereals and grains. DON is known to exert toxic effects on the gastrointestinal, reproductive and neuroendocrine systems, and particularly on the immune system. Depending on dose and exposure time, it can either stimulate or suppress immune function. The main objective of this study was to obtain a deeper insight into DON-induced effects on lymphoid cells. For this, we exposed the human T-lymphocyte cell line Jurkat and human peripheral blood mononuclear cells (PBMCs) to various concentrations of DON for various times and examined gene expression changes by DNA microarray analysis. Jurkat cells were exposed to 0.25 and 0.5 μM DON for 3, 6 and 24 h. Biological interpretation of the microarray data indicated that DON affects various processes in these cells: It upregulates genes involved in ribosome structure and function, RNA/protein synthesis and processing, endoplasmic reticulum (ER) stress, calcium-mediated signaling, mitochondrial function, oxidative stress, the NFAT and NF-κB/TNF-α pathways, T cell activation and apoptosis. The effects of DON on the expression of genes involved in ER stress, NFAT activation and apoptosis were confirmed by qRT-PCR. Other biochemical experiments confirmed that DON activates calcium-dependent proteins such as calcineurin and M-calpain that are known to be involved in T cell activation and apoptosis. Induction of T cell activation was also confirmed by demonstrating that DON activates NFATC1 and induces its translocation from the cytoplasm to the nucleus. For the gene expression profiling of PBMCs, cells were exposed to 2 and 4 μM DON for 6 and 24 h. Comparison of the Jurkat microarray data with those obtained with PBMCs showed that most of the processes affected by DON in the Jurkat cell line were also affected in the PBMCs. -- Highlights: ► The human T cell line Jurkat and human

  20. Don Quijote de la Mancha: Reflexiones en torno a las relaciones cine-literatura Don Quijote de la Mancha: Reflections about the relationships between cinematography-literature

    Directory of Open Access Journals (Sweden)

    Felipe Ardila Rojas

    2008-06-01

    Full Text Available Este artículo presenta un análisis de algunos aspectos de la relación cine-literatura, a partir del Don Quijote de La Mancha literario y de algunas versiones cinematográficas y televisivas realizadas en español y en inglés. Inicialmente se presentan problemas teóricos en torno a categorías que suelen serles afines: relato, autor, narración, historia, etc., para involucrar alternativamente fenómenos que, desde el punto de vista de los autores, generan ambigüedades textuales o múltiples interpretaciones en las versiones que se analizan. De este análisis comparativo que parte de los relatos en cuestión se llega finalmente a conclusiones de carácter estético e ideológico sobre los mismos.This article presents an analysis of some aspects of the relationship between cinematography and literature. Starting from the Don Quijote de La Mancha and taking into account some film and television versions developed in Spanish and English. At the beginning, a theoretical problem based on similar types for concepts categorization: author, narration, story, relat, among others will be analyzed. In addition, a connection is made with some authors' concepts in order to avoid textual ambiguity or multiple interpretations in the versions that are analyzed. Through a comparative analysis supported in these stories, it is possible to reach some aesthetic and ideological conclusions about them.

  1. Review of Ordering Don't Resuscitate in Iranian Dying Patients.

    Science.gov (United States)

    Cheraghi, Mohammad Ali; Bahramnezhad, Fatemeh; Mehrdad, Neda

    2018-06-01

    Making decision on not to resuscitate is a confusing, conflicting and complex issue and depends on each country's culture and customs. Therefore, each country needs to take action in accordance with its cultural, ethical, religious and legal contexts to develop guidelines in this regard. Since the majority of Iran's people are Muslims, and in Islam, the human life is considered sacred, based on the values of the community, an Iranian Islamic agenda needs to be developed not taking measures about resuscitation of dying patients. It is necessary to develop an Iranian Islamic guidelines package in order to don't resuscitate in dying patients.

  2. An Analysis of Insults in Don Quixote from the Perspective of Social History of Language

    Directory of Open Access Journals (Sweden)

    Jesús M. Usunáriz

    2017-11-01

    Full Text Available Daily use of insult, slander, in the societies of the Early Modern Age, is also present in the voices of the protagonists of Don Quixote. However, the Ingenious Gentleman and his squire, do not use the insult in the same way. This will depend on the social position of insulted and offender (noble or villain, and the circumstances surrounding it. However, social reality, collected in different court cases, shows that the insult did not respect, in the same way as in the novel, the stratified social structure.

  3. The Knight-errant and their Itinerary. Journey and />Death of Don Quixote

    Directory of Open Access Journals (Sweden)

    Nieves Rodríguez Valle

    2016-01-01

    Full Text Available This article analyzes, from the perspective of the hero’s journey topic in the narrative, the wanderings of Don Quixote on the Spanish roads and in the spaces of the chivalric literature. Based on the four narrative sequences that stake out the itinerary in the journey narrative: departure, cruise, meeting, and return, the three departures and the three returns of the knight in the work are reviewed, specially the last return and the relationship that it keeps with his death.

  4. Juan Bautista Avalle Arce y el escrutinio de la librería de Don Quijote

    OpenAIRE

    Nállim, Carlos Orlando

    2000-01-01

    En este trabajo se destacan los aportes de Avalle Arce a la crítica del Quijote que lo convierten en el "cervantista actual por antonomasia". Se señalan sus grandes aciertos: la peculiar tesis del crítico acerca de la relación que se establece entre vida y literatura; la influencia en la vida de Don Quijote no sólo de los libros de caballería sino también de muchos otros que conformaban su abundante biblioteca; la solución que aporta al trillado tema cordura/locura del personaje...

  5. Jasminum extensum Wall. ex G. Don (Oleaceace, a New Record to the Flora of Vietnam

    Directory of Open Access Journals (Sweden)

    Bui Hong Quang

    2013-06-01

    Full Text Available One rare, poorly known species from India, South China and Thailand - Jasminum extensum Wall. ex G. Don is recently discovered in Vietnam representing a new record to the flora of the country. The plant differs from its closely related species viz. Jasminum pierreanum in having coriaceous leaves and 5–6 primary veins in each side of the mid-rib. Detailed information on taxonomy, types, morphology, habitat, ecology, distribution and studied voucher specimens, as well as illustrations are provided here for species identification.

  6. Don José Joquín Casas : un hombre una época

    Directory of Open Access Journals (Sweden)

    Rafael Azula Barrera

    1966-03-01

    Full Text Available Debo a las generosas instancias del reverendo padre Félix Restrepo -cuyo tránsito terrenal, concluído al finalizar el año último, se halla constelado de hazañas que reclaman ser esculpidas, como alto relieves, en el propio pedestal de la estatua que la gratitud nacional habrá de levantar a su nombre el honor inmerecido de pronunciar las palabras de rigor, al conmemorar nuestro instituto, en este día del idioma, el primer centenario del nacimiento de don José Joaquín Casas.

  7. Chemical Composition and Possible in Vitro Phytotoxic Activity of Helichrsyum italicum (Roth Don ssp. italicum

    Directory of Open Access Journals (Sweden)

    Vincenzo De Feo

    2011-09-01

    Full Text Available The chemical composition of the essential oil of Helichrysum italicum (Roth Don ssp. italicum, collected in the National Park of Cilento and Diano Valley, Southern Italy, was studied by means of GC and GC/MS. Forty four compounds of 45 constituents were identified in the oil, mainly oxygenated sesquiterpenes. The essential oil was evaluated for its potential in vitro phytotoxic activity against germination and early radicle elongation of radish and garden cress. The radicle elongation of radish was significantly inhibited at the highest doses tested, while germination of both seeds was not affected.

  8. The invisible teenager: Comic book materiality and the amateur films of Don Glut

    Directory of Open Access Journals (Sweden)

    Matt Yockey

    2014-06-01

    Full Text Available Don Glut, between the ages of 9 and 25, made 41 short amateur films inspired by horror, science fiction, and superhero movies, serials, and comic books. The tactile qualities of comic books as affect-generating objects are instrumental to how Glut confirmed his identity during a time (adolescence in which that identity is particularly unstable. Glut used the popular figure of the teen rebel and his role as a filmmaker in order to negotiate with hegemonic restrictions on his objects of affection, especially comic books.

  9. The Landscape of Cervante´s Don Quixote: Orteguians Perspectives

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    Ángel Pérez Martínez

    2013-12-01

    Full Text Available Perspectival theory, related to Don Quixote by the many references in the corpus of Ortega, enables further research about the importance of the landscape and the physical description in order to understand the work of Cervantes. Similarly, it should be mentioned its relation with the development of literary theory. Such investigations give an interesting point of view under the framework called travel genre and its tangential contact with Quijote. On the other hand, and because of the publication of Obras Completas by Ortega, we find ourselves with a new order of the writings from the philosopher and an appropriate index for research.

  10. For the Amusement of the Merry Little Subjects: How British Children Met Don Quixote in the Long Eighteenth Century

    Directory of Open Access Journals (Sweden)

    Miriam Borham Puyal

    2015-12-01

    Full Text Available As a masterpiece, Don Quixote has become an easily recognizable myth, sometimes reduced to well-known episodes such as the tilting at windmills or the blanket-tossing of Sancho. These elements are emphasised in editions of this classic for children, highlighting the importance these versions have for the understanding of the widespread popularity of Cervantes’ novel, in general, and of certain scenes, in particular. The present article explores the relationship of the child reader to Don Quixote and provides an overview of how English children might have encountered it in the long eighteenth century (1660-1832. It connects chapbooks, abridgments and children’s books to suggest that children might have been among its earliest readers and to emphasise the intertextual continuum and the richness in the reception of Don Quixote in England, from the seventeenth to the nineteenth century.

  11. Gender differences in national assessment of educational progress science items: What does i don't know really mean?

    Science.gov (United States)

    Linn, Marcia C.; de Benedictis, Tina; Delucchi, Kevin; Harris, Abigail; Stage, Elizabeth

    The National Assessment of Educational Progress Science Assessment has consistently revealed small gender differences on science content items but not on science inquiry items. This assessment differs from others in that respondents can choose I don't know rather than guessing. This paper examines explanations for the gender differences including (a) differential prior instruction, (b) differential response to uncertainty and use of the I don't know response, (c) differential response to figurally presented items, and (d) different attitudes towards science. Of these possible explanations, the first two received support. Females are more likely to use the I don't know response, especially for items with physical science content or masculine themes such as football. To ameliorate this situation we need more effective science instruction and more gender-neutral assessment items.

  12. Bioanalysis of 6-Diazo-5-oxo-L-norleucine (DON) in plasma and brain by ultra-performance liquid chromatography mass spectrometry

    Science.gov (United States)

    Alt, Jesse; Potter, Michelle C.; Rojas, Camilo; Slusher, Barbara S.

    2015-01-01

    Glutamine is an abundant amino acid that plays pivotal roles in cell growth, cell metabolism and neurotransmission. Dysregulation of glutamine-utilizing pathways has been associated with pathological conditions such as cancer and neurodegenerative diseases. 6-Diazo-5-Oxo-L-Norleucine (DON) is a reactive glutamine analog that inhibits enzymes affecting glutamine metabolism such as glutaminase, 2-N-amidotransferase, L-asparaginase and several enzymes involved in pyrimidine and purine de novo synthesis. As a result, DON is actively used in preclinical models of cancer and neurodegenerative disease. Moreover, there have been several clinical trials using DON to treat a variety of cancers. Considerations of dose and exposure are especially important with DON treatment due to its narrow therapeutic window and significant side effects. Consequently, a robust quantification bioassay is of interest. DON is a polar unstable molecule which has made quantification challenging. Here we report on the characterization of a bioanalytical method to quantify DON in tissue samples involving DON derivatization with 3N HCl in butanol. The derivatized product is lipophilic and stable. Detection of this analyte by mass spectrometry is fast, specific and can be used to quantify DON in plasma and brain tissue with a limit of detection in the low nanomolar level. PMID:25584882

  13. Don Quijote y los eruditos: Sobre una polémica crítica y sus implicaciones metacríticas

    OpenAIRE

    Pardo García, Pedro Javier

    2000-01-01

    [ES]Este trabajo trata sobre Don Quijote y los eruditos: una polémica crítica y sus implicaciones metacríticas. [EN]This paper deals with Don Quixote and scholars: a critical controversy and its implications metacritica.

  14. Don Quijote y los eruditos: Sobre la sátira quijotesca de la pedantería en la literatura francesa del siglo XVIII

    OpenAIRE

    Pardo García, Pedro Javier

    1998-01-01

    [ES]Este texto trata Don Quijote y los eruditos, una polémica crítica y sus implicaciones metacríticas. [EN]This text is Don Quixote and scholars, a critical controversy and its implications metacritical.

  15. Don Yllán and the Egyptian Sorcerer: Vernacular commonality and literary diversity in medieval Castile

    Directory of Open Access Journals (Sweden)

    Wacks, David A.

    2005-12-01

    Full Text Available In this article the author compares the exemplo of Don Yllán and the Deán de Santiago -no. 11 in Don Juan Manuel's Conde Lucanor (ca. 1335- with an earlier Hebrew analogue found in the Hebrew Mešal Haqadmonī (ca. 1285 of fellow Castilian author Isaac ibn Sahula. A thorough analysis of the rhetorical and narrative style of both versions reveals that the two tales shared a common source in Castilian oral tradition. The appearance of the tale in an earlier Hebrew text from Castile (the only other known version in any language calls into question the originality of Don Juan Manuel's most famous exemplo, suggesting a productive interplay between a common oral tradition in Castilian and coexisting literary traditions in Hebrew and Castilian.

    En este artículo, el autor compara el exemplo de Don Yllán y el Deán de Santiago -n.° 11 en el Conde Lucanor (ca. 1335 de Don Juan Manuel- con una versión anterior en la obra hebrea, Mešal Haqadmonī (ca. 1285 de otro autor castellano, Isaac ibn Sahula. Un análisis cuidadoso del estilo narrativo y retórico de ambas versiones revela que las dos comparten una fuente común en la tradición oral castellana. La aparición del cuento en un texto hebreo anterior de Castilla (la única versión conocida en cualquier otra lengua cuestiona la originalidad literaria del más famoso exemplo de Don Juan Manuel, y sugiere un intercambio productivo entre una tradición oral común castellana y tradiciones literarias hebreas y castellanas coexistentes.

  16. DON shares a similar mode of action as the ribotoxic stress inducer anisomycin while TBTO shares ER stress patterns with the ER stress inducer Thapsigargin based on comparative gene expression profiling in Jurkat T cells

    NARCIS (Netherlands)

    Schmeits, P.C.J.; Katika, M.R.; Peijnenburg, A.A.C.M.; Loveren, van H.; Hendriksen, P.J.M.

    2014-01-01

    Previously, we studied the effects of deoxynivalenol (DON) and tributyltin oxide (TBTO) on whole genome mRNA expression profiles of human T lymphocyte Jurkat cells. These studies indicated that DON induces ribotoxic stress and both DON and TBTO induced ER stress which resulted into T-cell activation

  17. On the effects of the Fusarium toxin deoxynivalenol (DON) administered per os or intraperitoneal infusion to sows during days 63 to 70 of gestation.

    Science.gov (United States)

    Goyarts, Tanja; Brüssow, Klaus-Peter; Valenta, Hana; Tiemann, Ute; Jäger, Kathrin; Dänicke, Sven

    2010-05-01

    Six pregnant sows of 180.6 ± 5.6 kg were fed either a Fusarium-contaminated (4.42 mg DON and 48.3 µg ZON per kg, DON per os, n = 3) or a control diet (0.15 mg DON and 5 µg ZON/kg) in the period of days 63 and 70 of gestation. On day 63 of gestation, sows fed the control diet were implanted with an intraperitoneal osmotic minipump (delivery rate of 10 µL/h, for 7 days) containing 50 mg pure (98%) DON in 2 ml 50% DMSO (DON ip, n = 3). Frequent plasma samples were taken to estimate the kinetics after oral and ip DON exposure. The intended continuous delivery of DON by the intraperitoneal minipump could not be shown, as there was a plasma peak (Cmax) of 4.2-6.4 ng DON/mL either immediately (sow IP-2+3) or 2.5 h (sow IP-1) after implantation of the pump followed by a one-exponential decline with a mean half-time (t1/2) of 1.75-4.0 h and only negligible DON plasma concentrations after 12 h. Therefore, the DON ip exposure has to be regarded as one single dose 1 week before termination of experiment. The DON per os sows showed a mean basis level (after achieving a steady state) of DON plasma concentration of about 6-8 ng/mL, as also indicated by the plasma DON concentration at the termination of the experiment. On day 70, caesarean section was carried out, the fetuses were killed immediately after birth, and samples of plasma, urine, and bile were taken to analyze the concentration of DON and its metabolite de-epoxy-DON. At necropsy there were no macroscopic lesions observed in any organ of either sows or piglets. Histopathological evaluation of sows liver and spleen revealed no alterations. The proliferation rate of peripheral blood mononuclear cells (PBMC) with or without stimulation was not affected by the kind of DON treatment. The exposure of pregnant sows at mid-gestation (days 63-70, period of organogenesis) to a Fusarium toxin-contaminated diet (4.42 mg DON and 0.048 mg ZON per kg) or pure DON via intraperitoneal osmotic minipump

  18. The occurrence of Fusarium toxins (zearalenone, DON, fumonisin, and T2) in some food commodities and feedstuffs in Syria

    Energy Technology Data Exchange (ETDEWEB)

    Ghanem, I; Al-Arfe, M [Atomic Energy Commission, Damascus (Syrian Arab Republic). Dept. of Molecular Biology and Biotechnology

    2010-01-15

    The presence of four Fusarium toxins (namely, zearalenone, Don, fuminosin, and T2) was studied in 129 food commodities and feedstuff samples using an enzyme-linked immunosorbent assay (ELISA). Results showed that the percentages of wheat samples contaminated with T2, fuminosin, Don and Zearalenone were : 33%, 31%, 11.6% and 12.5% for each toxin, respectively. Concentrations of these toxins in the contaminated samples fell in the range of 81 - 350, 330 - 1330, 270 - 420 and 42-67 {mu}g kg-1 for each toxin respectively. Barely samples showed higher percentages of contamination with those toxins amounting to 75.9%, 83.3%, 75% and 83.3% with concentrations ranging between 89-145, 270 - 1230, 650 - 3450 and 42-102 {mu}g kg-1 for T2, , fuminosin, Don and Zearalenone, respectively. Percentages of contaminated bran samples were 80% for T2 and 100% for each of fumonisin, Don and zearalenone. Concentrations of T2, fuminosin, Don and Zearalenone in bran samples ranged between 81-322 , 510 - 1670 , 280 - 750 and 42-81 {mu}g kg-1, respectively. All four tested toxins were present in corn samples. Levels of T2, , fuminosin, Don and Zearalenone in corn samples were in the range of 112-426 , 730 - 1820, 590 - 1080 and 63-112 {mu}g kg-1, respectively. Similarly, 100% of examined soya seed cake samples were found contaminated with various levels of the four assayed toxins, with levels of contamination ranging between 98-142 , 1340 - 2220 , 330 - 800 and 93-114 {mu}g kg-1, for T2, , fuminosin, Don and Zearalenone, respectively. All cotton seed cake samples were contaminated with the four tested toxins with contamination levels ranging between 94 - 142, 1120 - 1920, 280 - 1340 and 56 - 132 {mu}g kg-1 for T2, , fuminosin, Don and Zearalenone, respectively. Only 87% of the composite pelletted feed samples were contaminated with zearalenone, but all of theme were contaminated with various levels of the other three tested toxins. (author)

  19. The occurrence of Fusarium toxins (zearalenone, DON, fumonisin, and T2) in some food commodities and feedstuffs in Syria

    International Nuclear Information System (INIS)

    Ghanem, I.; Al-Arfe, M.

    2010-01-01

    The presence of four Fusarium toxins (namely, zearalenone, Don, fuminosin, and T2) was studied in 129 food commodities and feedstuff samples using an enzyme-linked immunosorbent assay (ELISA). Results showed that the percentages of wheat samples contaminated with T2, fuminosin, Don and Zearalenone were : 33%, 31%, 11.6% and 12.5% for each toxin, respectively. Concentrations of these toxins in the contaminated samples fell in the range of 81 - 350, 330 - 1330, 270 - 420 and 42-67 μg kg-1 for each toxin respectively. Barely samples showed higher percentages of contamination with those toxins amounting to 75.9%, 83.3%, 75% and 83.3% with concentrations ranging between 89-145, 270 - 1230, 650 - 3450 and 42-102 μg kg-1 for T2, , fuminosin, Don and Zearalenone, respectively. Percentages of contaminated bran samples were 80% for T2 and 100% for each of fumonisin, Don and zearalenone. Concentrations of T2, fuminosin, Don and Zearalenone in bran samples ranged between 81-322 , 510 - 1670 , 280 - 750 and 42-81 μg kg-1, respectively. All four tested toxins were present in corn samples. Levels of T2, , fuminosin, Don and Zearalenone in corn samples were in the range of 112-426 , 730 - 1820, 590 - 1080 and 63-112 μg kg-1, respectively. Similarly, 100% of examined soya seed cake samples were found contaminated with various levels of the four assayed toxins, with levels of contamination ranging between 98-142 , 1340 - 2220 , 330 - 800 and 93-114 μg kg-1, for T2, , fuminosin, Don and Zearalenone, respectively. All cotton seed cake samples were contaminated with the four tested toxins with contamination levels ranging between 94 - 142, 1120 - 1920, 280 - 1340 and 56 - 132 μg kg-1 for T2, , fuminosin, Don and Zearalenone, respectively. Only 87% of the composite pelletted feed samples were contaminated with zearalenone, but all of theme were contaminated with various levels of the other three tested toxins. (author)

  20. La visión fantasiosa/caballeresca de Don Quijote poco representada en la iconografía

    OpenAIRE

    Calabrese, Martín Ezequiel

    2017-01-01

    En el presente trabajo se analizará un aspecto un tanto curioso de la representación iconográfica del Quijote. En casi la totalidad de las ediciones de la obra se omite representar la “realidad” percibida por don Quijote, optando por graficar la representación realista de los hechos narrados. En los diferentes modelos iconográficos de las ediciones de la obra este aspecto es común, ya que ante el texto, la decisión habitual de los editores e ilustradores es mostrar a don Quijote como “es” den...

  1. The Influence of Processing by Impulse Pressure on the Productivity of the Don Barley (Hordeum vulgare L.

    Directory of Open Access Journals (Sweden)

    Pavlova Violetta Aleksandrovna

    2014-04-01

    Full Text Available Plant productivity is the important indicator, which determines the amount of yield. The productivity of plants depends on the number of bruchids per plant and on the weight of 1000 bruchids. The article studies the influence of impulse pressure of various magnitudes on plant productivity of Don barley (Hordeum vulgare L.. It was found that the pressure of 17 MPa was the most effective for increasing the productivity. Impulse pressure of other magnitudes also had influence on the productivity of Don barley.

  2. Libros adquiridos por don Pedro Fermín de Vargas en sus viajes por las Antillas

    Directory of Open Access Journals (Sweden)

    Sergio Elías Ortíz

    1962-04-01

    Full Text Available Entre los papeles relacionados con la vida de Don Pedro Fermín de Vargas, que pueden consultarse en el Archivo General de Indias de Sevilla, hay una carta de él y una lista de libros que envía al Administrador de Correos de la Habana, Don José Fuertes, antiguo amigo suyo, luego su corresponsal y a la  vez espía de sus pasos para aprisionarlo, con el objeto de que se los guardase “en algún rincón de sus casa”.

  3. Don Quixote, Sweded by Michel Gondry in Be Kind Rewind (2008

    Directory of Open Access Journals (Sweden)

    Hogan Erin K.

    2017-12-01

    Full Text Available In the spirit of poetic license from Be Kind Rewind (2008, this article argues that Michel Gondry’s film “swedes,” its playful neologism for ersatz remaking of Hollywood and classic films, Miguel de Cervantes’s Don Quixote. The feature follows the Sanchification of Jerry (Jack Black, Gondry’s Don Quixote, and Quixotification of Mike (Mos Def, Gondry’s Sancho, as they nostalgically wrong cinematic rights through sweding and try to save their working-class neighbourhood from condemnation and gentrification through community film making. Gondry swedes the Quixote through his engagement with major themes and operations in Cervantes’s classic, including nostalgia, story-telling, conflicts between reality and fantasy, authorship, the grotesque and carnivalesque, (anti-heroes, race and gender-bending, genre, and addressees turned addressers. This article discusses Be Kind Rewind’s relationship to Hollywoodian and Cervantine classics through the theoretical frameworks of Julio Garcia Espinosa’s imperfect cinema and Foucauldian semiotics, respectively. Be Kind Rewind uses and abuses Hollywood stereotypes to re-purpose them for a critique of discriminatory practices. Where casting is concerned and where Michel’s characters diverge from Miguel’s, Be Kind Rewind advances that skin colour is not an arbitrary sign and that race has historical and contemporary meaning in intercultural interactions.

  4. Homenaje a Don Gregorio Marañon en el Centenario de su Nacimiento

    Directory of Open Access Journals (Sweden)

    Fernando Serpa Florez

    1987-12-01

    Full Text Available

    La Academia Nacional de Medicina rinde homenaje hoy a un español universal, don Gregorio Marañón y Posadillo (1887-1960 en el primer centenario de su nacimiento. Se asocia a la admiración y al orgullo que este hombre despierta por su inteligencia, su sabiduría y su obra entre sus gentes de España, con el entrañable afecto que su nombre evoca entre nosotros los iberoamericanos que también, a nuestra manera, lo sentimos nuestro.

    Médico, historiador, escritor, humanista, sociólogo y maestro, su espíritu se ensoñoreó por los campos abiertos del saber, descollando con méritos señeros en cada una de estas disciplinas. Y si en el presente siglo su par en la medicina podría ser don Santiago Ramón y Cajal, en las letras don José Ortega y Gassety en las humanidades don Miguel de Unamuno, por su bucear en las aguas profundas y lustrales de la historia su nombre es parangonable con el de españoles eternos con los que equiparó su vida: un Séneca, por su austero interrogar al destino y por el doloroso regustar del destierro (“carere patria intolerabili est”. Un san Isidoro de Sevilla, por su ecumenismo. Un Garcilaso de la Vega, por su poético enamoramiento de Toledo. Un Maimónides, por las enseñanzas de su saber médico y por los discípulos dejados en las más diversas latitudes unido a su excepcional amplitud de criterio -rara flor en la patria de Ignacio de Loyolay de don Felipe 11-; ausencia de ese dogmatismo y fanatismo que el mismo “espejo de los caballeros” hubo de sublimar en las brumas de su locura para ser el arquetipo de lo español y de España. Y un Miguel Servet, en fin, por sus paralelas intuiciones científicas, las de éste en la circulación de la sangre pulmonar, las de don Gregario en la endocrinología, las hormonas y las muy sutiles investigaciones del hasta hace poco coto vedado de la sexología y los estados intersexuales.

    Corresponderá al distinguido representante de la Sociedad

  5. 'Don't play the butter notes': jazz in medical education.

    Science.gov (United States)

    Bradner, Melissa; Harper, Darryl V; Ryan, Mark H; Vanderbilt, Allison A

    2016-01-01

    Jazz has influenced world music and culture globally - attesting to its universal truths of surviving, enduring, and triumphing over tragedy. This begs the question, what can we glean in medical education from this philosophy of jazz mentoring? Despite our training to understand disease and illness in branching logic diagrams, the human experience of illness is still best understood when told as a story. Stories like music have tempos, pauses, and silences. Often they are not linear but wrap around the past, future, and back to the present, frustrating the novice and the experienced clinician in documenting the history of present illness. The first mentoring lesson Hancock discusses is from a time he felt stuck with his playing - his sound was routine. Miles Davis told him in a low husky murmur, 'Don't play the butter notes'. In medical education, 'don't play the butter notes' suggests not undervaluing the metacognition and reflective aspects of medical training that need to be fostered during the early years of clinical teaching years.

  6. Don Quixote, Machiavelli, and Robin Hood: public health practice, past and present.

    Science.gov (United States)

    Mullan, F

    2000-05-01

    Since the mid-19th century, when the first formal health departments were established in the United States, commissioners, directors, and secretaries of public health have functioned as senior members of the staffs of public executives, mayors, governors, and presidents. They have provided important political, managerial, and scientific leadership to agencies of government that have played increasingly important roles in national life, from the sanitary revolution of the 19th century to the prevention of HIV/AIDS and the control of tobacco use today. Although public health officials come from a variety of backgrounds and oversee agencies of varied size and composition, there are philosophical themes that describe and define the commonality of their work. These themes are captured metaphorically by 3 celebrated figures: Don Quixote, Machiavelli, and Robin Hood. By turns, the public health official functions as a determined idealist (Don Quixote), a cunning political strategist (Machiavelli), and an agent who redistributes resources from the wealthier sectors of society to the less well off (Robin Hood.) All 3 personae are important, but, it is argued, Robin Hood is the most endangered.

  7. When Marcel Mauss's Essai sur le Don becomes The Gift: variations on the theme of solidarity.

    Science.gov (United States)

    Bateman, Simone

    2016-12-01

    Since the early 1970s, Marcel Mauss's Essai sur le Don (1923), translated into English as The Gift in 1954, has been a standard reference in the social science and bioethical literature on the use of human body parts and substances for medical and research purposes. At that time, three social scientists-political scientist Richard Titmuss in the United Kingdom and sociologist Renée C. Fox working with historian Judith Swazey in the United States-had the idea of using this concept to highlight the fundamental structure of the biomedical practices they were studying, respectively, blood donation, and hemodialysis and organ transplantation. The fact that these first applications of Mauss's essay should emerge in English- rather than in French-speaking countries raises the question of what the translation of the essay, and notably of the word don as gift, may have to do with this fact. Reading Mauss in translation undoubtedly inspired a seminal approach to interpreting medical and research practices based on bodily giving. This article posits that something may have also been lost: a much broader concept of giving with unquestionable links to the Durkheimian concept of solidarity, which Mauss conceptualizes not only as an obligation but also as a liberty to give.

  8. 77 FR 23673 - Notice of Stakeholder Meeting: Industry Roundtable-DON/USDA/DOE/DOT-FAA Advanced Drop-In Biofuels...

    Science.gov (United States)

    2012-04-20

    ...--DON/USDA/DOE/ DOT-FAA Advanced Drop-In Biofuels Initiative AGENCY: Department of the Navy, DoD. ACTION... participants in the biofuels supply chain. The purpose of the roundtable meeting is for the federal government... Biofuels Production Project. Questions related to the Special Notices or the pending Broad Agency...

  9. The Emperor Has No Clothes: Teaching about Race and Racism to People Who Don't Want to Know

    Science.gov (United States)

    Okun, Tema Jon

    2010-01-01

    "The Emperor Has No Clothes: Teaching About Race and Racism to People Who Don't Want to Know" is designed to offer both practical and theoretical grounding for leaders and teachers interested in effectively addressing racism as well as other oppressive constructs. The dissertation offers an overview of the role of western culture in maintaining…

  10. Fungsi Bangunan Dokwi Vam dan Kembu Vam Bagi Suku Yali dalam Novel Penguasa-penguasa Bumi Karya Don Richardson

    Directory of Open Access Journals (Sweden)

    Ummu Fatimah Ria Lestari

    2016-04-01

    Full Text Available This study discusses the function of the building of Dokwi Vam and Kembu Vam contained in the novel-Sovereign Ruler of the Earth works Don Richardson. In general, this novel tells the story of the life of Stan Dale and Yali tribe. Stan Dale is a missionary who served in Papua. He struggled to introduce Christianity to the Yali tribe. This study uses the description of the technical literature. This research resulted in a description of the function of the building of Dokwi Vam and Kembu Vam contained in the novel Lord of-Ruler of the Earth works Don Richardson. Dokwi Vam used as a museum (where the old stuff to worship as they still follow animism, while the Kembu Vam serves as a temple / animism worship in Yali tribe. Penelitian ini membahas tentang fungsi bangunan Dokwi Vam dan Kembu Vam yang terdapat dalam novel Penguasa-Penguasa Bumi karya Don Richardson. Secara umum, novel ini bercerita tentang kehidupan Stan Dale dan suku Yali. Stan Dale adalah seorang missionaris yang melayani di Tanah Papua. Ia berjuang untuk memperkenalkan agama Nasrani kepada suku Yali. Penelitian ini menggunakan metode deskripsi dengan teknik studi pustaka. Penelitian ini menghasilkan deskripsi tentang fungsi bangunan Dokwi Vam dan Kembu Vam yang terdapat dalam novel Penguasa-Penguasa Bumi karya Don Richardson. Dokwi Vam digunakan sebagai museum (tempat barang-barang kuno untuk penyembahan karena mereka masih menganut kepercayaan animisme, sedangkan Kembu Vam berfungsi sebagai rumah peribadatan/penyembahan dalam kepercayaan animisme suku Yali.

  11. Influencia de la poda en el desarrollo de masas de Pinus radiata D. Don y Pinus pinaster Aiton en Asturias

    OpenAIRE

    Hevia Cabal, Andrea

    2013-01-01

    Esta tesis evaluó la influencia de diferentes intensidades de poda sobre el crecimiento, desarrollo y persistencia de masas regulares jóvenes de Pinus radiata D. Don y Pinus pinaster Aiton en Asturias, dentro de una selvicultura sostenible enfocada a la producción de madera de calidad.

  12. Small ships don't shine: classification of ocean vessels from low resolution, large swath area SAR acquisitions

    CSIR Research Space (South Africa)

    Meyer, Rory GV

    2016-07-01

    Full Text Available the Understanding of Our Living Planet, 10-15 July 2016, Beijing, China Small ships don't shine: Classification of ocean vessels from low resolution, large swath area SAR acquisitions R. G. V. Meyer ; W. Kleynhans ; C. P. Schwegmann Abstract: Monitoring...

  13. Get Thee Away, Knight, Be Gone, Cavalier: English Translations of the Biscayan Squire Episode in "Don Quixote de la Mancha"

    Science.gov (United States)

    Azevedo, Milton M.

    2009-01-01

    This article analyzes twelve English translations of the Biscayan squire's speech ("Don Quijote de la Mancha", Chapter Eight) published between 1612 and 2000. The solutions found fall into three categories, namely (a) using standard English and risking misrepresenting the style of the original and omitting relevant cultural connotations, (b) using…

  14. Beat the Odds...Why Some Schools With Latino Children Beat the Odds and Others Don't

    Science.gov (United States)

    Waits, Mary Jo; Campbell, Heather E.; Gau, Rebecca; Jacobs, Ellen; Rex, Tom; Hess, Robert K.

    2006-01-01

    Using the methodology of Jim Collins from his book "Good to Great: Why Some Companies Make the Leap...and Other's Don't," the authors of this report, under the sponsorship of the Center for the Future of Arizona and the Morrison Institute, found 12 elementary and middle schools in Arizona--schools whose students are mostly Latino and…

  15. Naturally occurrence of Sr and Ca in the stem of a Japanese cedar (Cryptomeria japonica D. Don) using PIXE

    International Nuclear Information System (INIS)

    Katayama, Y.; Aoki, T.; Ko, S.; Yoshida, K.

    2000-01-01

    Distribution profiles of Sr and Ca occurring naturally in the stem of a Japanese cedar (Cryptomeria japonica D. Don) were determined using PIXE. The average concentration of Sr was around 7.5 ppm and the average Ca concentration was about 540 ppm. (author)

  16. Social and Political Activization of the Don Nobility in the Early 20th Century and “Noble Liberalism”

    Directory of Open Access Journals (Sweden)

    Bratolyubova Mariya Viktorovna

    2014-03-01

    Full Text Available Peculiarity of the social, economic and legal status of the Don nobility influenced its political alertness and the opposition character of activity. The liberal wing supported the creation of a new world outlook system which was expected to provide the basis for transforming the political system by means of gradual transition to people’s representatives or constitutional form of government. The liberal landowners insisted on the introduction of zemstvo (district council, the solution of the Cossack issue; they strived for liberalization of the military and bureaucratic control of the Cossack troops and demanded the withdrawal of civil government agencies from the competence of the Military department. The liberal nobility actively supported the change of conditions of service for the Cossacks and pressed for easier draft obligation and releasing the Cossack troops from police duties which clashed with the military dignity. The conservative type of liberalism prevailed within the noble class of the DHR that distanced itself from both the left and the right political forces. The liberalism of the Don nobles was also a reflection of social and cultural peculiarities of the Cossacks. The social basis of the Don liberalism differed from the common Russian analogs. As the Cossack class was rather numerous at the Don, and its representatives made up quite an important part of the regional liberal corporation, they influenced its tactics and the political programming considerably.

  17. The experience of strengthening subsidence of the soil under the existing building in the city of Rostov-on-Don

    Directory of Open Access Journals (Sweden)

    Prokopov Albert

    2017-01-01

    Full Text Available Described problem for multi-storey residential development in the city of Rostov-on-Don on collapsible soils. The analysis of the technical and technological peculiarities of solidification under conditions of maintained buildings. Examples of projects of consolidation subsidence of foundation soils of buildings in operation 50–70 years.

  18. Protien expression profiling of mouse thymoma upon exposure to the tricothecene deoxynivalenol (DON) Implications for its mechanism of action

    NARCIS (Netherlands)

    Osman, A.M.; Pennings, J.L.A.; Blokland, M.H.; Peijnenburg, A.A.C.M.; Loveren, van H.

    2010-01-01

    The objective of this work was to investigate whether proteomic analysis of thymoma cells treated with the trichothecene deoxynivalenol (DON) as compared to non-treated (control) cells would reveal differential protein expression, and thus would contribute to a better understanding of the mechanisms

  19. Enfermedad y muerte de Don Gonzalo Jiménez de Quesada

    Directory of Open Access Journals (Sweden)

    Fernando Serpa Florez

    1997-12-01

    Full Text Available

    La lepra es una enfermedad que se caracteriza por la insidia de su presencia, su lenta evolución y la progresiva incapacidad que en sus víctimas causa.

    Esto y el temor que ha infundido desde tiempos bíblicos, han hecho que ante ella se haya mantenido una actitud ambivalente de negación hasta donde es posible y de rechazo irracional a quien la padece, por temor al contagio.

    Ejemplo de ello es el aura de sagrado misterio que envuelve la leyenda de los padecimientos del Adelantado don Gonzalo Jiménez de Quesada (1509-1579, conquistador del Nuevo Reino de Granada y fundador de Santafé de Bogotá en el año de 1538, muerto a la edad, avanzada para la época, de setenta años.

    No se puede afirmar, en forma definitiva, que el conquistador fuera leproso. Se acepta, acogiendo el argumento de autoridad que tiene el primer historiador médico entre nosotros, don Pedro María Ibáñez, quien escribió en 1884, en las Memorias para la Historia de la Medicina en Santa Fe, que en “1579 falleció en la ciudad de Mariquita, y de mal de lepra o elefancía de los

    Coincide ello con lo que consigna don José María Vergara y Vergara en su Cuadro Cronológico de la Nueva Granada (hoi Estados Unidos de Colombia, desde los cipas hasta nuestros días (se ha conservado la ortografía usada a mediados del siglo XIX, preconizada por don Andrés Bello, estudio publicado en 1866, en que informa que a poco de posesionarse el tercer Presidente del Nuevo Reino, don Lope Díez Aux de Armendáriz: “ocurrió la muerte del adelantado Gonzalo Jiménez de Quesada que tuvo lugar en Mariquita el 16 de febrero de 1579, a la edad de ochenta años no cumplidos (sic, i de enfermedad de lepra (…” (2.

    Estos conceptos fueron debatidos por contemporáneos de Vergara y de Ibáñez como el doctor Juan de Dios Carrasquilla aduciendo, entre otros argumentos, que la lepra no fue mencionada por los coetáneos del conquistador. Y que la sífilis, com

  20. Deoxynivalenol (DON) is toxic to human colonic, lung and monocytic cell lines, but does not increase the IgE response in a mouse model for allergy

    International Nuclear Information System (INIS)

    Instanes, Christine; Hetland, Geir

    2004-01-01

    We examined whether the common crop mycotoxin deoxynivalenol (DON) from Fusarium species is toxic to human colonic (Caco-2), lung (A549) and monocytic (U937) cell lines. Moreover, since DON reportedly induces increased levels of Th2 cytokines and total IgE, and we have observed that mould extracts adjuvated allergy development in mice, possible adjuvant effect of DON on allergy was studied in a mouse model. For all the cells, exposure to DON for 24 h reduced cellular protein synthesis, proliferation and survival rate dose-dependently. In addition, production of IL-8 in the U937 cell line increased up to eight-fold at levels of DON just lower than the most toxic one, suggesting that IL-8 can be used as an additional index for cytotoxicity in mononuclear phagocytes. However, DON did not increase levels of allergen-specific IgE or IgG1 in the mouse model for allergy. These results suggest that DON, when inhaled or ingested, may have toxic effect on human alveolar macrophages and epithelial cells in lungs and colon, but does not increase the allergic response to allergens

  1. "Gathering Facts for the End of the World": Don DeLillo's Archive of Global Turbulence

    Directory of Open Access Journals (Sweden)

    Cornelius Collins

    2016-05-01

    Full Text Available Over his career, Don DeLillo grows to inhabit more complex and critical ideas about politics, capitalism, and strategies for opposition than the remote affect of his earlier work might suggest. As part of this project, he developed an advanced analysis of conditions under the global finance regimes gaining strength in the West. The author's papers at the Harry Ransom Center show that he arrived at this informed position through a program of independent research, his newspaper cuttings from this period vividly demonstrating reflections on the meaning of US global power. Once back in New York, his investment in public intellectual debates on the meaning of "terrorism" led to a characteristic but problematic emphasis on free speech as a political issue. More recently, his work has turned to sophisticated theoretical texts for increasingly subtle ideas about globalization and its opponents.

  2. Don Quijote goes to Hollywood: The rewrite of myth by Charles Chaplin

    Directory of Open Access Journals (Sweden)

    Esther Bautista Naranjo

    2015-12-01

    Full Text Available The character of Charlot, created by Charles Chaplin, rewrites the myth of don Quixote in silent movies. While sharing the roots of the picaresque tradition, they represent a harsh criticism of modernity in all its stages. A distinction has to be made between the plain vaudevillesque humor of Charlot in the brief comic strips from 1914 and its tragi-comical shaping in some short films from 1915 up to Modern Times (1936. Beyond their mere physical aspects and their hilarious exploits, an underlying tragic heroism and idealism lead them to uphold all good causes and to support the wronged ones while they also struggle for survival. Charlot combines the comic with the sublime and, as well as the ingenious hidalgo, his soul becomes gradually fuller, deeper and more human. For all these reasons, this character could be regarded as a “quixote” of the big screen.

  3. Le don gratuit. Le cas d'un établissement public

    OpenAIRE

    Barel , Yvan; Frémeaux , Sandrine

    2008-01-01

    Disponible en ligne : http://www.annales.org/gc/2008/gc94/barel.pdf; La logique de la réciprocité est le cadre d'analyse dominant de la relation de travail. La logique du don/contredon s'inscrit dans ce même cadre de référence, en postulant qu'aucune relation d'échange ne peut survivre à une situation d'asymétrie trop forte (MAUSS, 1924). Mais elle ajoute une idée nouvelle en mettant en exergue le " tabou du calcul " (BOURDIEU, 1980) : le désir de contredon n'est pas toujours manifesté, ni mê...

  4. Phase-change related epigenetic and physiological changes in Pinus radiata D. Don.

    Science.gov (United States)

    Fraga, Mario F; Cañal, Maria Jesús; Rodríguez, Roberto

    2002-08-01

    DNA methylation and polyamine levels were analysed before and after Pinus radiata D. Don. phase change in order to identify possible molecular and physiological phase markers. Juvenile individuals (without reproductive ability) were characterised by a degree of DNA methylation of 30-35% and a ratio of free polyamines to perchloric acid-soluble polyamine conjugates greater than 1, while mature trees (with reproductive ability) had 60% 5-methylcytosine and a ratio of free polyamines to perchloric acid-soluble polyamine conjugates of less than 1. Results obtained with trees that attained reproductive capacity during the experimental period confirmed that changes in the degree of DNA methylation and polyamine concentrations found among juvenile and mature states come about immediately after the phase change. We suggest that both indicators may be associated with the loss of morphogenic ability during ageing, particularly after phase change, through a number of molecular interactions, which are subsequently discussed.

  5. El don del agua, una obligacion moral y un interes de reconocimiento

    Directory of Open Access Journals (Sweden)

    Ana Patricia Quintana Ramírez

    2015-01-01

    Full Text Available En este artículo se presenta una discusión teórica en torno al análisis de la naturaleza y el interés de la economía del obsequio, así como el significado que tiene la práctica de donar agua en la sociedad.   Mediante el contraste argumentos y la referenciación de algunos casos empíricos, se concluye que el don del agua es una obligación moral en la esfera interpersonal, con un interés de acceso al reconocimiento social entre grupos humanos marginados del acceso al recurso. 

  6. Haplophyllum linifolium (L. G. Don fil: EAEn arriskuan dagoen landarearen kontserbazioa.

    Directory of Open Access Journals (Sweden)

    Asier Jáñez

    2017-01-01

    Full Text Available Haplophyllum linifolium (L. G. Don fil. Iberiar Penintsulako endemismoa da, Euskal Autonomia Erkidegoko flora mehatxatuaren zerrendan galtzeko arriskuan bezala katalogatzen dena. Ikerketa honen helburuak izan dira, batetik espezie honen hozidura protokoloak lortzea eta, bestetik, espezie horren hazien bideragarritasuna ikustea Tetrazolio Testaren bitartez. Horiek egitea ezinbestekoa zen espezie honen ex situ kontserbaziorako, baita landarearen hazkuntza egiteko ere etorkizunean in situ kontserbazio ekintzak egiteko, kasurako populazio indarketak. Alde batetik, lortutako hazien bideragarritasuna %64koa izan zen. Bestalde, hozidura protokolo egokienak zehaztu ziren, emaitzen analisi estatistikoa eginez R softwarearen bitartez, erregresio binomial logistikoaren ereduan oinarrituz. Lortutako hozidurak %43 eta %45 bitartekoak izan ziren, estratifikazio hotza (4ºC, 60 egun egin ondoren, ikasitako lau baldintzetan: 15ºC, 20ºC, 20/10ºC eta 25ºC, 12/12 ordu argi/iluntasun fotoperiodoekin.

  7. La Locura y el Buen Sentir de Don Quijote de la Mancha.

    Directory of Open Access Journals (Sweden)

    Adolfo de Francisco Zea

    2005-10-01

    La identidad de Alonso Quijano fue trazada borrosamente por Cervantes en la primera parte de su magistral novela. Tan sólo representa la imagen de uno de tantos hidalgos de una aldea española del siglo XVI: un hombre sencillo, bueno por antonomasia, “de complexión recia, seco de carnes, enjuto de rostro, gran madrugador y amigo de la caza”, y un lector fervoroso en sus horas de ocio y hastío que sólo llega a alcanzar con plenitud su identidad absoluta cuando tiene el vigor de transformarse en caballero andante de otros tiempos, en el Caballero de la Triste Figura como le llamó Sancho, en el valiente Caballero de la aventura de los leones, o simplemente en Don Quijote...

  8. [Age dynamics of population gene pool of the Crimean pine (Pinus pallasiana D. Don) in Crimea].

    Science.gov (United States)

    Korshikov, I I; Mudrik, E A; Krasnoshtan, O V; Velikorid'ko, T I; Kalafat, L A; Podgornyĭ, D Iu

    2011-01-01

    Polymorphism of young (14-16 years), middle-aged (70-80 years) and old (120-150 years) plants and their seed embryos has been studied using 20 and 10 allozyme loci correspondingly in the population of Pinus pallasiana D. Don from Mountain Crimea. It was revealed that the old-aged trees had significantly lower level of expected heterozygosity than the young plants. The level of observed heterozygosity of embryos of the uneven-aged plants was slightly different among the embryo samples and significantly lower than in the samples of maternal trees. Supernumerary homozygotation of the embryos is caused by low level of cross-pollination in three studied samples of plants (t(m) = 0,537-0,637).

  9. A phantom extinction? New insights into extinction dynamics of the Don-hare Lepus tanaiticus.

    Science.gov (United States)

    Prost, S; Knapp, M; Flemmig, J; Hufthammer, A K; Kosintsev, P; Stiller, M; Hofreiter, M

    2010-09-01

    The Pleistocene to Holocene transition was accompanied by a worldwide extinction event affecting numerous mammalian species. Several species such as the woolly mammoth and the giant deer survived this extinction wave, only to go extinct a few thousand years later during the Holocene. Another example for such a Holocene extinction is the Don-hare, Lepus tanaiticus, which inhabited the Russian plains during the late glacial. After being slowly replaced by the extant mountain hare (Lepus timidus), it eventually went extinct during the middle Holocene. Here, we report the phylogenetic relationship of L. tanaiticus and L. timidus based on a 339-basepair (bp) fragment of the mitochondrial D-loop. Phylogenetic tree- and network reconstructions do not support L. tanaiticus and L. timidus being different species. Rather, we suggest that the two taxa represent different morphotypes of a single species and the extinction of 'L. tanaiticus' represents the disappearance of a local morphotype rather than the extinction of a species.

  10. A propósito de don Andrés Bello

    Directory of Open Access Journals (Sweden)

    Carlos Restrepo Canal

    1965-09-01

    Full Text Available Al meditar en estos días sobre el insigne personaje de quien se conmemora el centenario de su fallecimiento -esto es de don Andrés Bello- al analizar su personalidad, estudiada y elogiada por tan autorizados y eruditos escritor es colombianos y extranjeros, al abrir de nuevo los muchos libros que contien en el variado conjunto de sus obras, se llega al convencimiento de que fue Bello como uno de aquellos grandes y brillantes varones del Renacimiento cuyas amplias facultades les hacían aptos para llegar al conocimiento de múltiples y variadas ramas del saber humano y para profundizar en ellas hasta llegar a constituirse en maestros y guías de las generaciones de su tiempo y de las que les sucedieron.

  11. War as Haiku: The Politics of Don DeLillo’s Late Style

    Directory of Open Access Journals (Sweden)

    Matthew Shipe

    2016-05-01

    Full Text Available In the wake of 'Underworld' (1997, Don DeLillo’s work has been cast largely in a minor key. In this essay, I will focus on 'Point Omega', the work that I believe most clearly illuminates the political implications of DeLillo’s late style as it tackles the consequences of the wars in Afghanistan and Iraq. More broadly, I hope to connect 'Point Omega' to the work of DeLillo’s contemporaries that have also speculated on the historical and political implications of the War on Terror. Centering on 'Point Omega', I am interested in how DeLillo has adopted a distinctive narrative form in his most recent fiction that frequently unsettles and complicates the historical narratives that he had established in his earlier work.

  12. Service quality improvement of ground staff at Don Mueang International Airport

    Directory of Open Access Journals (Sweden)

    Sittichai Sricharoenpramong

    2018-01-01

    Full Text Available The purposes of this research were to: 1 evaluate the service quality of the ground staff at Don Mueang International Airport (DMK, 2 compare the ground staff quality service perception of Thai passengers at DMK, and 3 provide guidelines for service quality improvement of the DMK airlines ground staff. A sample size of 400 Thai domestic passengers was accidentally selected at DMK. A questionnaire was used as a research tool for data collection. Five dimensions of service quality were evaluated: reliability, responsiveness, assurance, empathy, and tangibles. It was found that the service quality of ground staff was moderate. The highest dimension of service quality realization was tangibles, followed successively by reliability, assurance, empathy, and responsiveness. The passengers' perception of the ground staff's service quality varied by gender and age group. Guidelines were proposed for the improvement of ground staff service quality at DMK based on the findings. Keywords: airport, ground staff, quality of service

  13. Above-ground biomass equations for Pinus radiata D. Don in Asturias

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    E. Canga

    2013-12-01

    Full Text Available Aim of the study: The aim of this study was to develop a model for above-ground biomass estimation for Pinus radiata D. Don in Asturias.Area of study: Asturias (NE of Spain.Material and methods: Different models were fitted for the different above-ground components and weighted regression was used to correct heteroscedasticity. Finally, all the models were refitted simultaneously by use of Nonlinear Seemingly Unrelated Regressions (NSUR to ensure the additivity of biomass equations.Research highlights: A system of four biomass equations (wood, bark, crown and total biomass was develop, such that the sum of the estimations of the three biomass components is equal to the estimate of total biomass. Total and stem biomass equations explained more than 92% of observed variability, while crown and bark biomass equations explained 77% and 89% respectively.Keywords: radiata pine; plantations; biomass.

  14. Is the Partner the Don Quixote of the 21st Century Corporate World?

    DEFF Research Database (Denmark)

    Bévort, Frans; Poulfelt, Flemming

    2015-01-01

    A large and growing proportion of the organizations in the contemporary knowledge economy are organized as professional partnerships as is the case of professional service firms (PSFs). As these firms have grown larger (e. g. Big4: Deloitte, PwC, E&Y, KPMG), the way of organizing is under pressure...... for change. This raises the question of whether the Partner ownership and management model is a relic of the past - and the partner a Don Quixote-figure of the 21st century corporate world? Based on an ethnographic study of a PSF in Denmark, and data from other sources, the paper analyzes the changing...... organization of work, the changing partner and manager roles and basic changes in the HR-model. The dilemma the paper highlights is the tension between a still more centralized and efficiency oriented management and the basic need for development of professional human resources and leadership. The paper sees...

  15. Size, Albedo, and Taxonomy of the Don Quijote Space Mission Target

    Science.gov (United States)

    Harris, Alan; Mueller, Michael; Fitzsimmons, Alan

    2006-03-01

    Rendezvous and lander missions are a very effective but very expensive way of investigating Solar-System bodies. The planning, optimization and success of space missions depends crucially on prior remotely-sensed knowledge of target bodies. Near-Earth asteroids (NEAs), which are mainly fragments of main-belt asteroids, are seen as important goals for investigation by space missions, mainly due to the role their forebears played in planet formation and the evolution of the Solar System, but also for the pragmatic reason that these objects can collide with the Earth with potentially devastating consequences. The European Space Agency is currently planning the Don Quijote mission to a NEA, which includes a rendezvous (and perhaps a lander) spacecraft and an impactor vehicle. The aim is to study the physical properties of the target asteroid and the effects of the impact on its dynamical state, as a first step in considering realistic mitigation measures against an eventual hazardous NEA. Two potential targets have been selected for the mission, the preferred one being (10302) 1989 ML, which is energetically easier to reach and is possibly a scientifically interesting primitive asteroid. However, due to the ambiguity of available spectral data, it is currently not possible to confidently determine the taxonomic type and mineralogy of this object. Crucially, the albedo is uncertain by a factor of 10, which leads to large uncertainties in the size and mass and hence the planned near-surface operations of Don Quijote. Thermal-infrared observations are urgently required for accurate size and albedo determination. These observations, which can only be carried out by Spitzer and would require only a modest amount of observing time, would enable an accurate diameter to be derived for the first time and the resulting albedo would remove the taxonomic ambiguity. The proposed Spitzer observations are critical for effective mission planning and would greatly increase our

  16. Evaluation of the clinical maxim: "If it ain't broke, don't fix it".

    Science.gov (United States)

    Howell-Duffy, Chris; Hrynchak, Patricia K; Irving, Elizabeth L; Mouat, Graham S V; Elliott, David B

    2012-01-01

    A significant number of patients return to optometric practice dissatisfied with their spectacles. An important question is whether any of these cases are preventable. There are several different clinical maxims that are used to modify the subjective refraction when determining the refractive prescription. These maxims aim to improve patient comfort and adaptation and thereby reduce patient dissatisfaction with new spectacles. They are not based on research evidence, but rather on expert opinion gained from clinical experience. The aim of this study was to retrospectively analyze a large number of case records of dissatisfied patients to assess the possible usefulness of the prescribing maxim "if it ain't broke, don't fix it." Three hundred eighteen non-tolerance cases from a university-based Canadian optometric clinic were categorized by a focus group of optometrists. Three prescribing categories were defined and comprised cases in which application of the proposed maxim may have prevented the recheck eye examination; a more limited application of the maxim for one working distance may have been appropriate; and finally scenarios in which the maxim did not work in that the practitioner was judged to have initially followed the maxim, yet patient dissatisfaction was still reported. The remaining unallocated records comprised prescribing situations outside the scope of this study. Approximately 32% of non-tolerance cases were judged to have been preventable by use of the proposed maxim. Furthermore, an additional 10% reduction in recheck cases may have been possible by a more liberal interpretation of the maxim. Conversely, 4% of cases were deemed to comprise scenarios in which the maxim was followed yet the patient returned later to report problems with their spectacles. The prescribing maxim "if it ain't broke, don't fix it" appears to have a role in reducing recheck eye examinations and improving patient satisfaction with new spectacles.

  17. «Red Ritualism» in the Territory of Don Oblast in 1923-1924

    Directory of Open Access Journals (Sweden)

    Tabunshchikova Liudmila

    2015-12-01

    Full Text Available The birth, development and extinction peculiarities of the “Red Ritualism” (new traditions and rituals of Soviet Russia in the territory of Don Oblast in 1923–1924 are considered in this article on the basis of the regional periodicals of 1920. The Soviet Government was interested in new ritualism from the first revolution years till the beginning of 1930 and in the period of the Khrushchev Thaw (the end of the 1950 — the beginning of the 1960 . The article is devoted to the investigation of theses processes at the regional level in the first half-year of the 1920. The struggle with survives of time was on of the most evident areas of the anti-religious activity of the Goverment in the fi rst half-year of the 1920 th. After the company of church values confiscation the Government stroke an ideological blow at the way of life — they created “civil funeral”, “red marriage” and “octyabriny” (a name-day, the soviet ritual as an alternative of christening. In the Don region theses rituals appeared in 1923. “The red christening” was the most popular, “the civil funeral” was the least one. These processes were mostly spread in the cities and in a less degree in the villages. While in the whole country in 1925 the interest toward the “red ritualism” reached the peak, in the Donskaya oblast it was fading away. The author in this work uses the archive materials that were not published previously. The article will be useful for the specialists and other people interested in the given subject.

  18. El Quijote y el fenómeno del quijotismo (Don Quixote and Quixotism Phenomenon

    Directory of Open Access Journals (Sweden)

    Jesús Ruiz Fernández

    2013-12-01

    Full Text Available Resumen: Estudia el presente artículo el fenómeno del quijotismo, ingrediente de la razón, y, por tanto, del comportamiento humano. Pero distingue entre el error del quijotismo estático y el sano proceder del dinámico. Para ello se vale del concepto de razón vital de Ortega y Gasset, así como del Quijote. Con respecto al primero, amplía la utilización que de la magna obra podía haber hecho y no hizo el ilustre filósofo. Y sobre el segundo, destaca sus insuficiencias de contenido, por no haber alcanzado el quijotismo dinámico, es decir, porque, queriendo criticar el idealismo desmedido del caballero manchego, termina por proponer otro quijote. De cualquier forma, el artículo señala cómo el irónico fenómeno del quijotismo no es un juego, para lo cual discute ciertas interpretaciones recientes del Quijote.Abstract: This article studies Quixotism phenomenon, ingredient of vital reason, and, consequently, of human behaviour. However, it distinguishes between the mistake of static quixotism and the right conduct of the dynamic one. In order to do so, it makes use of Ortega y Gasset's concept of Vital Reason, and Don Quixote’s as well. Concerning the first one, it highlights the insufficiency of its content since it has not fulfilled the dynamic quixotism, that is to say, because, with the intention to criticize La Mancha’s Knight’s excessive idealism, it ends up proposing other quixotic person. Anyway, this article points out how the ironic quixotism phenomenon is not a game, for which reason it discusses certain Don Quixote’s recent interpretations.

  19. Don Quijote en Brasil: de la mitología a las historietas

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    Kenia Almeida Pereira

    2009-11-01

    Full Text Available Este artículo es una pequeña reflexión sobre el libro El ingenioso hidalgo Don Quijote de la Mancha, de Miguel de Cervantes, publicada en 1605. Esta obra ha sido considerada como una de las mejores novelas de todos los tiempos. En ella podemos transitar de lo popular a lo erudito. Esta narrativa está llena de antítesis y metáforas barrocas que contienen desde los refranes populares hasta la erudición de los mitos griegos, así como de la locura y jocosidad de Don Quijote y también de la mediocridad y lucidez de Sancho Panza.

  20. Diseño del código de convivencia para el Colegio Técnico Salesiano Don Bosco - Kennedy

    OpenAIRE

    Aguilar Acosta, Andrea Anabel; Puga Reyes, Denis Gicela

    2013-01-01

    The Coexistence’s Code delivered to The Don Bosco Technical Salesian High School, is an instrument that is going to work as moral and ethical framework to govern and regulate relationships between each member of the educational community so that they can achieved institutional objectives presents in Institutional Educational Project. El presente Código de Convivencia entregado al Colegio Técnico Salesiano “Don Bosco” – Kennedy; es un instrumento que funcionara como marco referencial, moral...

  1. Application of gamma radiation to the nodes detection in Pinus Radiata (D.Don) wood pieces; Aplicacion de la radiacion gamma en la deteccion de nudos en piezas de madera de Pino Radiata (D.Don)

    Energy Technology Data Exchange (ETDEWEB)

    Morales, J R; Dinator, Maria I [Chile Univ., Santiago (Chile). Dept. de Fisica; Karsulovic C, Jose T; Leon G, Adolfo [Chile Univ., Santiago (Chile). Dept. de Tecnologia de la Madera

    1997-12-31

    Attenuation of 59.5 KeV photons provided by an Am-241 source, has been used to detect knots in lumber pieces from Pinus Radiata (D.Don). It is shown that the linear attenuation coefficient is a sensitive parameter to detect singularities in the structure of this material. The scanning of the piece provides profiles which define the position and extension of the singularity. (author). 7 refs.

  2. The Discoveries and Achievements of Modern Historiography of the Don Cossacks in the Second Half of the XIX Century

    Directory of Open Access Journals (Sweden)

    Oleg E. Chuikov

    2016-09-01

    Full Text Available The article examines the current historiography of the Don Cossacks in the second half of the XIX century, there is described the traditional and the alternative concepts advanced by historians after 2000 year. The article analyses the main studies on this chronological period, their advantages and disadvantages. It is shown that many of the events and reforms are not sufficiently understood so far. The authors note that the increase in the number of specialists on Don history of 1860–1890 should be considered the major trend in the development of modern historiography of this period, and it is hoped that the range of the studied issues will only expand in the future, and the level and number of publications revealing new facts and offering new concepts will continue to grow.

  3. Mitigation-relevant science with Don Quijote - a European-led mission to a near-Earth asteroid

    Science.gov (United States)

    Harris, A. W.; Galvez, A.; Benz, W.; Fitzsimmons, A.; Green, S. F.; Michel, P.; Valsecchi, G.; Paetzold, M.; Haeusler, B.; Carnelli, I.

    The Don Quijote concept includes a rendezvous spacecraft and an impactor vehicle The main aim of the mission is to carry out an experiment to demonstrate the modification of a near-Earth asteroid s orbit in a controlled way as a first step in establishing mitigation measures against an eventual hazardous object In particular the spacecraft would study the physical properties of the target asteroid and the effects of a kinetic impact on its dynamical state It is also expected that some spacecraft resources will be available for more general solar-system science investigations The Don Quijote mission is currently at the phase-A stage during which a number of European consortia of industrial and scientific partners will study its technical feasibility and potential scientific return The basic mission concept current scientific issues and the possibilities for international participation in the mission will be discussed

  4. Don Quixote and the Auditor from México: a disagreement between a knight and a gentleman

    Directory of Open Access Journals (Sweden)

    María Eugenia Mayer

    2009-12-01

    Full Text Available Don Quixote’s first adventure, the combat with the Basque, and his last one, in which he meets the Auditor, both deal with a «knight»/gentleman who is leaving for the West Indies. The opposite pole of the Manchego knight is the gentleman appointed to the Audience of New Spain, ca. 1600, during Lerma’s Privacy. This lawyer/auditor hears two «cases»: the «strange humor» of the Manchegan, as told by the priest who has found an anonymous manuscript; and the «unnexpected business» of his future son-in-law, who will accompany him to Mexico, heir to a title. The Oidor’s discreet proceedings contrast with Don Quixote’s open proclaims, thus serving as key to a bicostal (Spain/Indies reading of the

  5. Measurement of injected Sr in the stem of a Japanese cedar (Cryptomeria japonica D. Don) using PIXE

    International Nuclear Information System (INIS)

    Katayama, Y.; Aoki, T.; Ko, S.; Yoshida, K.

    1999-01-01

    Distribution profiles of Sr injected into the stem of a Japanese cedar (Cryptomeria japonica D. Don) were determined using PIXE. The Sr injected into the middle of the sapwood of the cedar stem moved upwards easily along the grain. The Sr in the stem moved in a radial direction in the sapwood section (assumed to be through the ray) and there was almost no tangential movement. (author)

  6. Condition and Organization of Everyday Life in the Military Units of the Southwestern, Stalingrad and Don fronts (1942–1943

    Directory of Open Access Journals (Sweden)

    Tatiana P. Khlynina

    2015-03-01

    Full Text Available The article is devoted to various aspects of the condition and organization of the everyday life of military units of the Southwestern, Stalingrad and Don fronts in 1942–1943 years. The looks of the questions of food and clothing supplies, ensure domestic needs and recreation. At the base of the article are documents of the Central Archive of the Ministry of Defense of the Russian Federation, recorded memories participants in the events of that time, published sources.

  7. Preparation and analysis of carbonization products from Sugi (Cryptomeria japonica D. Don) wood; Sugi (Cryptomeria japonica D. Don) zai no tanka seiseibutsu no chosei to bunseki

    Energy Technology Data Exchange (ETDEWEB)

    Matsui, T.; Matsushita, Y.; Sugamoto, K.; Tokuda, Y. [Miyazaki University, Miyazaki (Japan). Faculty of Engineering; Kodama, K.; Nakata, K.; Oda, M.; Yamauchi, H. [Miyazaki Prefectural Institute of Industrial Technology, Miyazaki (Japan)

    2000-01-10

    The material balance of carbonization products (wood-gas, wood-vinegar, wood-tar and charcoal) prepared from the sapwood and the heartwood of Sugi (Cryptomeria japonica D. Don) at various temperatures was determined. The evolution of both carbon monoxide and carbon dioxide mainly occurred at the carbonization temperature below 600 degree C and that of hydrogen and methane at 600-800 degree C. Total yield of the wood-vinegar and the wood-tar was almost constant at 500-800 degree C. On the other hand, the yield of the charcoal decreased because of the evolution of the wood gas with an increase in carbonization temperature. The wood-vinegars prepared at the temperature over 400 degree C were found to consist of carboxylic acids such as acetic acid and propionic acid, methanol, acetone, furans, alkylphenols, guaiacols, cyclotene and maltol by capillary gas chromatography. Since the constituent varieties and contents of the wood-vinegars prepared at both 400 degree C and 800 degree C were very similar each other, the wood-vinegar of Sugi wood chiefly produced below 400 degree C. FT-IR spectra of the charcoals showed the generation of carbonyl and olefin groups at 300-400 degree C and then the formation of aromatic rings along with the disappearance of carbonyl groups over 600 degree C. The production of radical species in the charcoals carbonized at 300-600 degree C was observed by ESR, on the contrary, the charcoals carbonized over 700 degree C were inactive. The specific surface area and the pore volume of the charcoal of Sugi sapwood increased with an increase in carbonization temperature. The pH of charcoal-dispersed aqueous solution increased with an increase in carbonization temperature. The high adsorptive activity of the charcoal carbonized at 400 degree C for ammonia gas and that at 800 degree C for hydrogen sulfide gas seemed to be dependent on acidic and basic properties of the charcoals, respectively. (author)

  8. Chivalry, Materialism, and the Grotesque in Don Quijote and Alberto Blest Gana’s El ideal de un calavera

    Directory of Open Access Journals (Sweden)

    Vilches Patricia

    2017-01-01

    Full Text Available This study analyses chivalry, materialism, and the grotesque in Alberto Blest Gana’s El ideal de un calavera [The Ideal of a Rogue] (1863 under the light of Miguel de Cervantes’s Don Quijote’s part II (1615. It underscores the legacy of Cervantes on the Chilean author especially in his reflections on nation building. Unlike its author, Don Quijote eluded restriction and successfully reached the colonies; once there, author and text became a massive influence on intellectuals in the burgeoning Americas. Blest Gana, for example, created protagonists who were multi-dimensional and imbued with quixotic overtones. Praised by his counterparts, he created work that was finely detailed, with a goal of portraying the nation’s cultural practices at specifics points in history. Deploying techniques inspired by Honore de Balzac (also a reader of Don Quijote, Blest Gana illustrated the colourful aspects of his society. His sharp eye depicted and interpreted nationhood and society through the course of dramatic historical events in El ideal de un calavera by shining a bright light on the political and social enemies who emerged in the historical unravelling of the nation in the 1830s. The resulting kaleidoscope of astute, idealistic and cowardly individuals conveyed subtle yet definite Cervantesque tones.

  9. Dissolved organic nitrogen (DON) losses from nested artificially drained lowland catchments with contrasting soil types

    Science.gov (United States)

    Tiemeyer, Bärbel; Kahle, Petra; Lennartz, Bernd

    2010-05-01

    Artificial drainage is a common practice to improve moisture and aeration conditions of agricultural land. It shortens the residence time of water in the soil and may therefore contribute to the degradation of peatlands as well as to the still elevated level of diffuse pollution of surface water bodies, particularly if flow anomalies like preferential flow cause a further acceleration of water and solute fluxes. Especially in the case of nitrate, artificially drained sub-catchments are found to control the catchment-scale nitrate losses. However, it is frequently found that nitrate losses and nitrogen field balances do not match. At the same time, organic fertilizers are commonly applied and, especially in lowland catchments, organic soils have been drained for agricultural use. Thus, the question arises whether dissolved organic nitrogen (DON) forms an important component of the nitrogen losses from artificially drained catchments. However, in contrast to nitrate and even to dissolved organic carbon (DOC), this component is frequently overlooked, especially in nested catchment studies with different soil types and variable land use. Here, we will present data from a hierarchical water quantity and quality measurement programme in the federal state Mecklenburg-Vorpommern (North-Eastern Germany). The monitoring programme in the pleistocene lowland catchment comprises automatic sampling stations at a collector drain outlet (4.2 ha catchment), at a ditch draining arable land on mineral soils (179 ha), at a ditch mainly draining grassland on organic soils (85 ha) and at a brook with a small rural catchment (15.5 km²) of mixed land use and soil types. At all sampling stations, daily to weekly composite samples were taken, while the discharge and the meteorological data were recorded continuously. Water samples were analyzed for nitrate-nitrogen, ammonium-nitrogen and total nitrogen. We will compare two years: 2006/07 was a very wet year (P = 934 mm) with a high summer

  10. El arzobispado de Don Gonzalo de Aguilar en Santiago de Compostela (1348-1351

    Directory of Open Access Journals (Sweden)

    Sánchez Sánchez, Xosé M.

    2010-06-01

    Full Text Available In the middle of the 14th century the prelature of Santiago de Compostela is occupied by Don Gonzalo de Aguilar, archbishop transferred from Sigüenza and whose pontificate is extended between 1348 and 1351, when he is transferred to Toledo. He is a figure that remained until now in the complete darkness of the history of the Compostellan church, disappearing in fact, in many cases, of the historical considerations, that they avoided him or simply they did not have noticed of his figure, extending the bordering prelatures (Peter V and Gómez Manrique until eliminate his one. It responds to the completely absence of sources and mentions in the Compostellan archives; in order to palliate this fact, we resorted to the bibliography of other seats and, specially, to the sources of the Vatican Secret Archive, with whose aid we can form one first, new and relatively complete vision of its reign in Santiago.

    A mediados del siglo XIV ocupa el arzobispado de Santiago de Compostela Don Gonzalo de Aguilar, prelado trasladado desde Sigüenza y cuyo pontificado se extiende entre los años 1348 y 1351, momento en que es promovido a Toledo. Se trata de una figura que permanecía hasta ahora en la completa penumbra de la historia de la iglesia compostelana, hasta el punto de haber desaparecido en muchos casos de las consideraciones históricas, que obviaban o simplemente desconocían su figura, extendiendo las prelaturas limítrofes, las de Pedro V y Gómez Manrique, hasta eliminar la suya. Ello responde a la completa falta de fuentes y menciones existente en los archivos compostelanos. Para paliar este hecho, recurrimos tanto a la bibliografía de otras sedes como, especialmente, a las fuentes del Archivo Secreto Vaticano, con cuya ayuda podemos configurar una primera, novedosa y relativamente completa visión de su gobierno en Santiago.

  11. El infante don Gabriel y el impresor Ibarra en la obra cumbre del Salustio

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    Olaechea Labayen, Juan B.

    1997-04-01

    Full Text Available Not available.En la obra conocida como el «Salustio de Ibarra», considerada por especialistas domésticos y foráneos como la mejor impresa en España, convergen circunstancias relevantes debidas a la participación intelectual del infante don Gabriel de Borbón y la eficiencia técnica de Joaquín Ibarra. El autor reivindica la autenticidad de los textos atribuidos al infante contra cierto escepticismo sembrado en razón de la elevada alcurnia de la atribución. Seguidamente, se realiza el análisis de las cualidades técnicas de la impresión, eminentes en una época de esplendor del arte impresorio, y en cuya confección colaboraron los más descollantes artistas del buril de aquel período considerado de triunfo de la estampa ilustrada.

  12. The Presence of Don Quijote in the Beginnings of the Special Education in Galicia

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    Ana Rodríguez Díaz

    2015-12-01

    Full Text Available This article aims to show the presence of the work of Cervantes, “Don Quijote de la Mancha”, in the unique establishments existing in Galicia at the beginning of the 20th century, dedicated to special education. According to this claim, reference is made to two significant anniversaries in the dissemination of the work. The first one corresponds to the commemoration of the third centenary of the birth of the Cuisse. In this Establishment one would organize in the year 1905, in the free School of blind persons and poor children of To Corunna. A very complete festival as appears in the content of the program, which has recovered of the historical municipal file of the above mentioned city. The second event, refers to the presentation of the novel by Cervantes, written in Braille. Quite a challenge for teachers in special schools of the time, as the College of deaf and blind from Santiago de Compostela, the first school for the teaching of these students, which is established in Spain for the purposes of the law of public instruction of 1857, will assume early.

  13. Development and characterization of a green procedure for apigenin extraction from Scutellaria barbata D. Don.

    Science.gov (United States)

    Yang, Yu-Chiao; Wei, Ming-Chi

    2018-06-30

    This study compared the use of ultrasound-assisted supercritical CO 2 (USC-CO 2 ) extraction to obtain apigenin-rich extracts from Scutellaria barbata D. Don with that of conventional supercritical CO 2 (SC-CO 2 ) extraction and heat-reflux extraction (HRE), conducted in parallel. This green procedure yielded 20.1% and 31.6% more apigenin than conventional SC-CO 2 extraction and HRE, respectively. Moreover, the extraction time required by the USC-CO 2 procedure, which used milder conditions, was approximately 1.9 times and 2.4 times shorter than that required by conventional SC-CO 2 extraction and HRE, respectively. Furthermore, the theoretical solubility of apigenin in the supercritical fluid system was obtained from the USC-CO 2 dynamic extraction curves and was in good agreement with the calculated values for the three empirical density-based models. The second-order kinetics model was further applied to evaluate the kinetics of USC-CO 2 extraction. The results demonstrated that the selected model allowed the evaluation of the extraction rate and extent of USC-CO 2 extraction. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. Don Cossack Army Charters of the Mid 18th Century Via the Category of Modality

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    Elena Mihaylovna Sheptukhina

    2015-12-01

    Full Text Available The article deals with the language means of modality in the texts of military charters of the mid 18th cent. from the "Mikhailovsky stanitza hetman" archive (State Achieve of Volgograd Region. Military charters used to be major documents of legislation within Don Cossack Host, as being at that time an administrative unit in the territory of Russian Empire. The results of the contextual analysis verify the following facts: the charter texts are mainly characterized by an imperative tone of regulation that is caused by coordination between dominant meanings of a propositional (situational modality of necessity and pragmatic modality of volition, that are thought to be interrelated in utterances. The modal meaning of necessity is marked by the verbal construction with an independent infinitive or the combinations of modal verbs (imet' / possess; nadlezhat' / be to, modal predicatives with a dependent infinitive (dolzhen, nadobno, etc. / must (have to. Modality of volition is presented with a set of lexical units that possess the meanings of ordering, permission, offers, verbal forms that are used as performatives, or point to the status of a subject, etc. The texts under study represent some other modal meanings: possibility (with the words moch' / be able to; mozhno / could / may combined with an infinitive, in subordinate clauses with a particle li (if / wether, etc. in an interrogative clauses. In complex sentences with subordination combinations of various modal meanings are observed.

  15. Don't be such a scientist talking substance in an age of style

    CERN Document Server

    Olson, Randy

    2009-01-01

    How to relate scientific information in a way that entertains and enlightens? After twenty years as a marine biologist, a Ph.D. from Harvard, a tenured professorship at the University of New Hampshire, and more than twenty published research papers, why is Dr. Randy Olson telling readers, 'Don't Be Such a Scientist'? The hard-earned advice comes from a fifteen-year career transition to filmmaking, culminating in the acclaimed documentaries "Flock of Dodos: The Evolution-Intelligent Design Circus" and "Sizzle: A Global Warming Comedy". In his first book, Olson makes clear what those glued to their microscopes and climate models may not recognize: the general public doesn't speak science. For better or worse, most of us rely not on intellect, but on what Olson terms the organs of mass communication: the heart, the gut, and even 'the lower organs'. Why else do some still question the existence of global warming or evolution when the evidence is irrefutable? Drawing on his own hilarious - and at times humiliating...

  16. Nuclear power plant transient diagnostics using artificial neural networks that allow ''don't-know'' classifications

    International Nuclear Information System (INIS)

    Bartal, Y.; Lin, J.; Uhrig, R.E.

    1995-01-01

    A nuclear power plant's (NPP's) status is usually monitored by a human operator. Any classifier system used to enhance the operator's capability to diagnose a safety-critical system like an NPP should classify a novel transient as ''don't-know'' if it is not contained within its accumulated knowledge base. In particular, the classifier needs some kind of proximity measure between the new data and its training set. Artificial neural networks have been proposed as NPP classifiers, the most popular ones being the multilayered perceptron (MLP) type. However, MLPs do not have a proximity measure, while learning vector quantization, probabilistic neural networks (PNNs), and some others do. This proximity measure may also serve as an explanation to the classifier's decision in the way that case-based-reasoning expert systems do. The capability of a PNN network as a classifier is demonstrated using simulator data for the three-loop 436-MW(electric) Westinghouse San Onofre unit 1 pressurized water reactor. A transient's classification history is used in an ''evidence accumulation'' technique to enhance a classifier's accuracy as well as its consistency

  17. Cellular modelling of secondary radial growth in conifer trees: application to Pinus radiata (D. Don).

    Science.gov (United States)

    Forest, Loïc; Demongeot, Jacques; Demongeota, Jacques

    2006-05-01

    The radial growth of conifer trees proceeds from the dynamics of a merismatic tissue called vascular cambium or cambium. Cambium is a thin layer of active proliferating cells. The purpose of this paper was to model the main characteristics of cambial activity and its consecutive radial growth. Cell growth is under the control of the auxin hormone indole-3-acetic. The model is composed of a discrete part, which accounts for cellular proliferation, and a continuous part involving the transport of auxin. Cambium is modeled in a two-dimensional cross-section by a cellular automaton that describes the set of all its constitutive cells. Proliferation is defined as growth and division of cambial cells under neighbouring constraints, which can eliminate some cells from the cambium. The cell-growth rate is determined from auxin concentration, calculated with the continuous model. We studied the integration of each elementary cambial cell activity into the global coherent movement of macroscopic morphogenesis. Cases of normal and abnormal growth of Pinus radiata (D. Don) are modelled. Abnormal growth includes deformed trees where gravity influences auxin transport, producing heterogeneous radial growth. Cross-sectional microscopic views are also provided to validate the model's hypothesis and results.

  18. Performance of a new 3D-only PET scanner - the EXACT3D

    International Nuclear Information System (INIS)

    Spinks, T.J.; Bailey, D.L.; Miller, M.

    1996-01-01

    Characteristics of currently the highest sensitivity 3D-only PET scanner (CTI/Siemens 966/EXACT3D) have been studied. The device has 48 rings (82cm diameter) of BGO detector elements (4.0 x 4.1 x 30mm, 8 x 8 block) and an axial FOV of 23.4cm. Attenuation correction is carried out with a point source of 137 Cs which moves under hydraulic pressure in a helical tube. Transaxial resolution is 4.7mm 1cm from the centre of the FOV increasing, in the radial direction to 6.3mm and 7.3mm at 10cm and 15cm. At a lower threshold of 350keV, the scatter fraction is 40%. With scatter subtracted, the efficiency (20cm cylinder) is 6.9 x 104 cps/kBq/ml (maximum ring difference of 40); the absolute sensitivity is 5.8%. In the current configuration, the maximum total coincidence event rate is limited to about 3 x 10 6 per sec. The maximum trues rate is about 850kcps (90MBq in the FOV). List mode acquisition has been implemented to maximize temporal resolution and optimize data storage. The more open geometry of this device gives a broader singles FOV. Hence administered doses and/or additional side-shielding need to be carefully considered to optimize noise-equivalent counts

  19. Proteomic profiling of proteins associated with the rejuvenation of Sequoia sempervirens (D. Don Endl

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    Chen Yu-Ting

    2010-12-01

    Full Text Available Abstract Background Restoration of rooting competence is important for rejuvenation in Sequoia sempervirens (D. Don Endl and is achieved by repeatedly grafting Sequoia shoots after 16 and 30 years of cultivation in vitro. Results Mass spectrometry-based proteomic analysis revealed three proteins that differentially accumulated in different rejuvenation stages, including oxygen-evolving enhancer protein 2 (OEE2, glycine-rich RNA-binding protein (RNP, and a thaumatin-like protein. OEE2 was found to be phosphorylated and a phosphopeptide (YEDNFDGNSNVSVMVpTPpTDK was identified. Specifically, the protein levels of OEE2 increased as a result of grafting and displayed a higher abundance in plants during the juvenile and rejuvenated stages. Additionally, SsOEE2 displayed the highest expression levels in Sequoia shoots during the juvenile stage and less expression during the adult stage. The expression levels also steadily increased during grafting. Conclusion Our results indicate a positive correlation between the gene and protein expression patterns of SsOEE2 and the rejuvenation process, suggesting that this gene is involved in the rejuvenation of Sequoia sempervirens.

  20. Visual Grading and Structural Properties Assessment of Large Cross-Section Pinus radiata D. Don Timber

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    Eva Hermoso Prieto

    2016-04-01

    Full Text Available The use of large cross-section timber for structural purposes has increased in Spain, and knowledge of its properties is strategically necessary. The Spanish visual strength-grading standard UNE 56544 (2011 efficiency applied to large cross-section structural timber was analyzed using a sample of 363 specimens of radiata pine (Pinus radiata D. Don. from the Basque Country and Catalonia, Spain. Different sizes were tested (80 × 120 × 2400 mm3, 150 × 250 × 5600 mm3, 150 × 250 × 4300 mm3, and 200 × 250 × 5000 mm3. Bending strength, modulus of elasticity, and density were obtained, and characteristic values were determined in order to assign strength class according to European standard EN 338 (2010. Knots and twists were the most relevant singularities for visual strength grading. It was concluded that large cross-section Spanish radiata pine timber was suitable for structures, and it was assigned to the C20 strength class.

  1. 60 years of CERN at UNESCO | Don't miss the webcast! | 1 July

    CERN Multimedia

    2014-01-01

    Don't miss the live webcast of the commemoration ceremony, marking the signature of the CERN Convention. The ceremony will be held at the UNESCO Headquarters in Paris on 1 July, from 10 a.m.   To watch the webcast, please visit: http://webcast.web.cern.ch/webcast/ from 10 a.m. Programme 10 a.m. - 11 a.m.: Opening of Ceremony by Maciej Nalecz, Director of the Division of Science Policy and Capacity Building, UNESCO   Address by Irina Bokova, Director-General of UNESCO   Address by Rolf Heuer, Director-General of CERN   Video clip “CERN: 60 years of science for peace”   Address by Agnieszka Zalewska, President of the CERN Council   Hommage à François de Rose, un des pères fondateurs du CERN, par sa fille Laurence Rousselot   CERN as seen by a young phycisist, Claire Lee (ATLAS Collaboration) 11 a.m. - 12 p.m.: Roundtable discussion on “Science for...

  2. Mutagenicity and antimutagenicity of Salacia crassifolia (mart. Ex. Schult. G. Don. evaluated by Ames test

    Directory of Open Access Journals (Sweden)

    C. C. Carneiro

    2017-09-01

    Full Text Available Abstract Salacia crassifolia (Mart. Ex. Schult. G. Don. is a bush which belongs to Celastraceae family and occurs specially in Brazilian Cerrado. Its leaves, stem, seeds and fruits are popularly used for several medicinal purposes, such as antitumoral, antirheumatic, anti-inflammatory and antimicrobial. In this study, the mutagenic and antimutagenic activities of S. crassifolia stem bark fractions (hexane, ethyl acetate and hydroalcoholic were evaluated by the Ames mutagenicity assay in Salmonella typhimurium TA98 and TA100 strains. By the obtained results, all S. crassifolia fractions did not significantly increase the number of prototrophic revertants for histidine (His+ in both S. typhimurium strains tested (p > 0.05, suggesting absence of mutagenicity. Regarding antimutagenicity, the fractions ethyl acetate and hydroalcoholic significantly decreased the number of His+ revertants colonies induced by positive control for strain TA98 (p < 0.05, demonstrating protection against mutagenicity induced by 4-nitroquinolile1-oxide, whereas the hexane fraction did not show antimutagenic effect in this strain. In the TA100 strain, all fractions of S. crassifolia protected DNA against the harmful action of sodium azide, and the hexane fraction exhibited the greatest protection in this work. Thus, it’s possible conclude that the fractions of S. crassifolia tested in this study could be used in chemoprevention.

  3. Anatomical characters of the phyllode and stem of Acacia podalyriifolia A. Cunn. ex G. Don (Fabaceae

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    M.R. Duarte

    Full Text Available The Acacia genus has presented various secondary metabolites, such as tannins, flavonoids, alkaloids and gums. Preparations from different species have been applied for diabetes, gastrointestinal disorders and inflammatory diseases in the traditional medicine and have demonstrated cytotoxic, antimicrobial and antiparasitic activities. Acacia podalyriifolia A. Cunn. ex G. Don (Fabaceae is a small wood, indigenous to Australia and cultivated worldwide for its ornamental feature. This work aimed to characterize the anatomy of the phyllode and stem, in order to contribute to the species identification. The botanical material was fixed, sectioned and prepared according to usual light and scanning microtechniques. The epidermal cells, in surface view, are polygonal and coated with striate and thick cuticle, and filaments of epicuticular wax. Paracytic stomata and unicellular non-glandular trichomes are seen. Palisade and ground parenchymas, and minor collateral bundles with xylem directed alternately to upper and lower sides occur in the blade. The midrib shows two collateral bundles facing each other. The stem, in incipient secondary growth, exhibits epidermis, annular collenchyma, sclerenchymatic sheath and collateral vascular organization. Cells containing phenolic compounds and prisms of calcium oxalate are observed.

  4. The Nazarov Complex of the Lower Don: on Zoroastrianism of the Khazar Ethnos

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    Leonid S. Ilyukov

    2017-10-01

    Full Text Available Among the early medieval antiquities of the Lower Don basin, two funerary complexes are of interest. One was accidentally discovered in 1914 in the Cossack village Nazarov, and the other – near the settlement Bolshaya Orlovka in 1972. Based upon the Byzantine solidities, found in their inventory, they date from the first half of the 8th century. Two iron lamps in the form of bowls on a high leg were found in these funerary complexes along with a diverse and prestigious inventory. In addition to them, two iron composite altars of different sizes were found in the Bolshaya Orlovka. In the early medieval burial mound near the Brusyana village in the Volga region a solidcast iron lamp-altar was found, consisting of a bowl in the form of a concave disc on a long leg, which was welded in the center of a hexagonal bowl with low straight sides and a flat bottom. Short legs are located at its three corners. Typologically Brusian discovery was later then those of the Nazarov and the Bolshaya Orlovka. It unites the altar, consisting of threebowls with low straight bows and a flat bottom, with a lamp. Short legs are located at its three corners of the bowls. These were specific bowls that were used to carry fire during rituals of steppe nomads who had close cultural contacts with the fire worshipers of Sasanid Iran, whose population professed Zoroastrianism.

  5. DOC and DON Dynamics along the Bagmati Drainage Network in Kathmandu Valley

    Science.gov (United States)

    Bhatt, M. P.; McDowell, W. H.

    2005-05-01

    We studied organic matter dynamics and inorganic chemistry of the Bagmati River in Kathmandu valley, Nepal, to understand the influence of human and geochemical processes on chemical loads along the drainage system. Population density appears to be the most fundamental control on the chemistry of surface waters within the Bagmati drainage system. DOC concentration increases 10-fold with distance downstream (from 2.38 to 23.95 mg/L) and shows a strong relationship with human population density. The composition of river water (nutrients, Cl) suggests that sewage effluent to the river has a major effect on water quality. Concentrations were highest during summer, and lowest during the winter monsoon season. In contrast to DOC, DON concentration shows surprisingly little variation, and tends to decrease in concentration with distance downstream. Ammonium contributes almost all nitrogen in the total dissolved nitrogen fraction and the concentration of nitrate is negligible, probably due to rapid denitrification within the stream channel under relatively low-oxygen conditions. Decreases in sulfate along the stream channel may also be due to the reduction of sulfate to sulfide due to the heavy organic matter loading. Water quality is unacceptable for any use and the whole ecosystem is severely affected within the urban areas. Based on a comparison of downstream and upstream water quality, it appears that human activities along the Bagmati, principally inputs of human sewage, are largely responsible for the changes in surface water chemistry within Kathmandu valley.

  6. Analysis of the Gaia RVS Region in ESPaDOnS Spectra of Asteroseismic Calibration Stars

    Science.gov (United States)

    Vesa, Oana; Huber, Daniel; Gaidos, Eric

    2018-01-01

    While surface gravity can be measured from asteroseismology, asteroseismology cannot be applied to every star. Surface gravity is a critical stellar parameter because it can be used to calculate the radii of stars, which is important in the characterization of host stars of exoplanets. Here we present spectroscopic observations from ESPaDOnS on the Canada-France-Hawaii Telescope of 172 benchmark “gold standard” stars observed by the NASA Kepler Mission for which densities and surface gravities have been precisely measured using asteroseismology. The goal is to discover an empirical correlation between the equivalent width of the spectral lines in the infrared Ca II triplet region (from 8470 to 8710 angstroms) against surface gravity and other stellar parameters, such as effective temperature and metallicity. The Mg I line at 8736 angstroms has the best potential to be an indicator of surface gravity so far out of the spectral lines in this region with equivalent width increasing slightly as a function of surface gravity; however, degeneracies with effective temperature and metallicity need to be explored further. If a true indicator for surface gravity can be found, then it can to be applied to the R~11000 Gaia radial velocity spectra, which will be released for millions of stars over the coming years.

  7. What consumers don't know about genetically modified food, and how that affects beliefs.

    Science.gov (United States)

    McFadden, Brandon R; Lusk, Jayson L

    2016-09-01

    In the debates surrounding biotechnology and genetically modified (GM) food, data from consumer polls are often presented as evidence for precaution and labeling. But how much do consumers actually know about the issue? New data collected from a nationwide U.S. survey reveal low levels of knowledge and numerous misperceptions about GM food. Nearly equal numbers of consumers prefer mandatory labeling of foods containing DNA as do those preferring mandatory labeling of GM foods. When given the option, the majority of consumers prefer that decisions about GM food be taken out of their hands and be made by experts. After answering a list of questions testing objective knowledge of GM food, subjective, self-reported knowledge declines somewhat, and beliefs about GM food safety increase slightly. Results suggest that consumers think they know more than they actually do about GM food, and queries about GM facts cause respondents to reassess how much they know. The findings question the usefulness of results from opinion polls as a motivation for creating public policy surrounding GM food.-McFadden, B. R., Lusk, J. L. What consumers don't know about genetically modified food, and how that affects beliefs. © FASEB.

  8. Shattering Man’s Fundamental Assumptions in Don DeLillo’s Falling Man

    Directory of Open Access Journals (Sweden)

    Hazim Adnan Hashim

    2016-09-01

    Full Text Available The present study addresses effects of traumatic events such as the September 11 attacks on victims’ fundamental assumptions. These beliefs or assumptions provide individuals with expectations about the world and their sense of self-worth. Thus, they ground people’s sense of security, stability, and orientation. The September 11 terrorist attacks in the U.S.A. were very tragic for Americans because this fundamentally changed their understandings about many aspects in life. The attacks led many individuals to build new kind of beliefs and assumptions about themselves and the world. Many writers have written about the human ordeals that followed this incident. Don DeLillo’s Falling Man reflects the traumatic repercussions of this disaster on Americans’ fundamental assumptions. The objective of this study is to examine the novel from the traumatic perspective that has afflicted the victims’ fundamental understandings of the world and the self. Individuals’ fundamental understandings could be changed or modified due to exposure to certain types of events like war, terrorism, political violence or even the sense of alienation. The Assumptive World theory of Ronnie Janoff-Bulman will be used as a framework to study the traumatic experience of the characters in Falling Man. The significance of the study lies in providing a new perception to the field of trauma that can help trauma victims to adopt alternative assumptions or reshape their previous ones to heal from traumatic effects.

  9. Don Draper Thinks Your Ad Is Cliché: Fairy Tale Iconography in TV Commercials

    Directory of Open Access Journals (Sweden)

    Preston Wittwer

    2016-05-01

    Full Text Available When examining the history of fairy tale iconography in advertising, folklore scholar Donald Haase’s fairy tale encyclopedia compared the Pied Piper of Hamelin to a symbol of advertising who could “play his pipe ever so sweetly and the consumers following him without resisting his charming and manipulative music.” In contrast, a 2012 episode of Mad Men, advertising luminary Don Draper shoots down a shoe commercial pitch featuring Cinderella, calling the idea “cliché”. The temptation for advertisers to rely on fairy tale figures and iconography continues today and many ignore Don’s aversion for cliché because it still gets the job done. However, there are some ads featuring fairy tales which avoid cliché and are truly innovative for their time. I’ll examine how, and for whom, these fairy tale figures have been adapted decade by decade in order to examine popular culture’s commercialized and hypnotic relationship with fairy tales in the most direct format available: television commercials.

  10. "Don't know" answers concerning somatic disease status should not be regarded as "no" responses

    Directory of Open Access Journals (Sweden)

    Baumeister, Harald

    2008-06-01

    Full Text Available Background: With regard to patients' self-reported somatic diseases some researchers transformed “don't know (DK” responses into “no” responses. The present study examines the appropriateness of this procedure. Methods: Analyses were based on the nationally representative German National Health Interview and Examination Survey (GHS, which assessed both self-reported diseases and physician-diagnosed diseases (N = 7124. Prevalence rates of persons’ DK responses and the corresponding prevalences of physicians’ diagnoses were calculated for persons with hypertension, coronary heart disease (CHD, heart failure, asthma, chronic bronchitis, thyroid disease, diabetes, cancer, gout, arthrosis, arthritis and osteoporosis. Correlates of physicians' diagnosed diseases of DK cases are reported. Results: Between 1.6% and 9.8% of the participants responded with DK to the question of whether they have the disease. In 3.7% to 29.5% of DK cases, the physicians did regard the respective disease as being present. With regard to persons who responded with DK, the probability of a physicians' diagnosis was increased in the case of increased age and a higher number of somatic comorbidities. Conclusion: The procedure of transforming DK responses into “no” answers does not appear to be recommendable.

  11. La sombra del arcediano. El linaje oculto de don Lorenzo Galíndez de Carvajal

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    Baltasar CUART MONER

    2009-11-01

    Full Text Available RESUMEN: D. Lorenzo Galíndez de Carvajal fue un personaje destacado en la Corte de los Reyes Católicos y Carlos V, además de cronista real. Sin embargo, para alcanzar esta posición tuvo que manipular sus orígenes familiares, siendo como era hijo de un arcediano de Coria y de una moza de servicio en una posada. Las manipulaciones de don Lorenzo tuvieron el éxito apetecido, sin embargo, treinta años después de su muerte, las informaciones realizadas sobre un nieto suyo que quería ingresar en el Colegio Mayor de Oviedo, en Salamanca, sacaron a la luz toda la estrategia familiar que tuvo que poner en marcha su ilustre abuelo para alcanzar la posición a la que llegó.ABSTRACT: D. Lorenzo Galíndez de Carvajal was one of the most influential courtiers at the Catholic King's court. He, too, was one of their chroniclers, but he had to forge his familiar origins in order to hold his job. He was an illegitimate son; his father was an archdeacon in Coria and his mother a maidservant. D. Lorenzo Galíndez de Carvajal succeeded in hiding his origins and his descendants became related to nobility by marriage. Howeyer all his grandfather's impostures and the ways followed by aristocracy to manipulate its origins were discovered when one of his grandsons tried to be admitted to the Oviedo College about the middle of the XVIth century.

  12. The Fusarium graminearum Histone Acetyltransferases Are Important for Morphogenesis, DON Biosynthesis, and Pathogenicity

    Directory of Open Access Journals (Sweden)

    Xiangjiu Kong

    2018-04-01

    Full Text Available Post-translational modifications of chromatin structure by histone acetyltransferase (HATs play a central role in the regulation of gene expression and various biological processes in eukaryotes. Although HAT genes have been studied in many fungi, few of them have been functionally characterized. In this study, we identified and characterized four putative HATs (FgGCN5, FgRTT109, FgSAS2, FgSAS3 in the plant pathogenic ascomycete Fusarium graminearum, the causal agent of Fusarium head blight of wheat and barley. We replaced the genes and all mutant strains showed reduced growth of F. graminearum. The ΔFgSAS3 and ΔFgGCN5 mutant increased sensitivity to oxidative and osmotic stresses. Additionally, ΔFgSAS3 showed reduced conidia sporulation and perithecium formation. Mutant ΔFgGCN5 was unable to generate any conidia and lost its ability to form perithecia. Our data showed also that FgSAS3 and FgGCN5 are pathogenicity factors required for infecting wheat heads as well as tomato fruits. Importantly, almost no Deoxynivalenol (DON was produced either in ΔFgSAS3 or ΔFgGCN5 mutants, which was consistent with a significant downregulation of TRI genes expression. Furthermore, we discovered for the first time that FgSAS3 is indispensable for the acetylation of histone site H3K4, while FgGCN5 is essential for the acetylation of H3K9, H3K18, and H3K27. H3K14 can be completely acetylated when FgSAS3 and FgGCN5 were both present. The RNA-seq analyses of the two mutant strains provide insight into their functions in development and metabolism. Results from this study clarify the functional divergence of HATs in F. graminearum, and may provide novel targeted strategies to control secondary metabolite expression and infections of F. graminearum.

  13. Don Delillo’s Point Omega; Ecstasy and Inertia in a Hyperreal World: A Baudrillardian Reading

    Directory of Open Access Journals (Sweden)

    Faeze Yegane

    2015-07-01

    Full Text Available This paper aims to present a Baudrillardian reading of Don Delillo’s Point Omega in the framework of Baudrillard’s definition of the contemporary world as ‘hyperreal’ and also his twin concepts of ‘ecstasy and inertia’. According to Baudrillard, the contemporary time is the hyperreal era in which subjects do not have access to ‘real’ primarily because they are supplied with the ‘simulations’ first and then with the ‘real’ entity and probably never confronted with the ‘real’ itself through media, advertisements, and virtual world. Thus, the perception they have from incidents, objects, places and even other people is ‘hyperreal’; edited, censored, beautified and exaggerated versions of reality; more real than real. In this study Point Omega will be examined as Delillo’s ‘hyperreal’ version of Alfred Hitchcock’s Psycho since the movie is screened in the course of the novel and despite the similarities between the novel and the movie they end contrastingly. Symbolically ‘real’ is not found in the novel due to ‘Mobius spiraling negativity’ which is one of the features of Baudrillard’s definition of ‘hyperreal’ age. Baudrillard believes in the triumph of objects over subjects. While the object’s world is perpetually cultivating frenziedly, objects and technologies begin to dominate the stupefied subjects consequently he states when the objects are moving toward their ‘ecstasy’, the subjects are stricken in ‘inertia’. This supremacy of objects and technologies will be displayed in Point Omega regarding Richard Elster’s inert behavior and reaching the ‘omega point’ that Teilhard de Chardin envisions for human race is rendered impossible due to Elster’s destiny in the framework of Baudrillard’s concept of evolution.

  14. Climate as possible reproductive barrier in Pinus radiata (D. Don interspecific hybridisation

    Directory of Open Access Journals (Sweden)

    Hannél Ham

    2017-12-01

    Full Text Available Historically, interspecific hybridisation with Pinus radiata D. Don had limited success. The effect of environmental conditions and position of pollination bags in the tree were investigated as possible hybridisation barriers. The study was conducted in a P. radiata seed orchard in the Southern Cape (South Africa. Field data were compared to the climatic conditions at natural and commercial provenances of seven Mesoamerican Pinus species identified as possible hybrid partners. In vitro pollen studies were used to confirm whether interspecific crosses with P. radiata might be feasible within predefined climatic parameters. The temperature ranges for both top and northern side of P. radiata pine trees in the seed orchard was similar to the natural distribution of P. radiata, P. elliottii Engelm. and P. taeda L. in the USA. Results suggested that pollen of P. elliottii and P. taeda might be more suited to result in the successful pollination of P. radiata than the other Mesoamerican pine species tested in this study.  Furthermore, the combination of minimum temperature and precipitation also showed a closer correlation to successful hybridisation with P. radiata for both P. elliotii and P. taeda. However, pollen tube elongation studies did not support these results, suggesting that mean temperature might not be the only determining factor of hybridisation success. Three circadian temperature models that mimic natural conditions were developed for Karatara and Sabie (Tweefontein, Witklip and Spitskop.  These models will be tested in future in vitro studies to further evaluate temperature fluctuations between day and night regimes as a possible reproductive barrier limiting hybridisation success between P. radiata and other Mesoamerican pine species.

  15. Supercritical Extraction of Scopoletin from Helichrysum italicum (Roth) G. Don Flowers.

    Science.gov (United States)

    Jokić, Stela; Rajić, Marina; Bilić, Blanka; Molnar, Maja

    2016-09-01

    The increasing popularity of immortelle (Helichrysum italicum (Roth) G. Don) and its products, particularly in the cosmetic industry, is evident nowadays. This plant is a source of coumarins, especially scopoletin, which are highly soluble in supercritical CO2 . The objective of this study was to perform the supercritical CO2 extraction process of Helichrysum italicum flowers at different values of pressure and temperature and to optimise the extraction process using response surface methodology in terms of obtaining the highest extraction yield and yield of extracted scopoletin. Extraction was performed in a supercritical extraction system under different extraction conditions of pressure and temperature determined by central composite rotatable design. The mass of flowers in the extractor of 40 g, extraction time of 90 min and CO2 mass flow rate of 1.94 kg/h were kept constant during experiments. Antioxidant activity was determined using the DPPH (1,1-diphenyl-2-picrylhydrazyl) free radical scavenging assay method. Scopoletin concentration was determined by HPLC. Changes in extraction conditions affect the extracting results remarkably. The greatest extraction yield (6.31%) and the highest yield of scopoletin (1.933 mg/100 g) were obtained under extraction conditions of 20 MPa and 40°C. Extracts have also proven to possess antioxidant activity (44.0-58.1% DPPH scavenging activity) influenced by both temperature and pressure applied within the investigated parameters. The extraction conditions, especially pressure, exhibited significant influence on the extraction yield as well as the yield of extracted scopoletin and antioxidant activity of extracts. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  16. Selection of Reliable Reference Genes for Gene Expression Studies on Rhododendron molle G. Don.

    Science.gov (United States)

    Xiao, Zheng; Sun, Xiaobo; Liu, Xiaoqing; Li, Chang; He, Lisi; Chen, Shangping; Su, Jiale

    2016-01-01

    The quantitative real-time polymerase chain reaction (qRT-PCR) approach has become a widely used method to analyze expression patterns of target genes. The selection of an optimal reference gene is a prerequisite for the accurate normalization of gene expression in qRT-PCR. The present study constitutes the first systematic evaluation of potential reference genes in Rhododendron molle G. Don. Eleven candidate reference genes in different tissues and flowers at different developmental stages of R. molle were assessed using the following three software packages: GeNorm, NormFinder, and BestKeeper. The results showed that EF1- α (elongation factor 1-alpha), 18S (18s ribosomal RNA), and RPL3 (ribosomal protein L3) were the most stable reference genes in developing rhododendron flowers and, thus, in all of the tested samples, while tublin ( TUB ) was the least stable. ACT5 (actin), RPL3 , 18S , and EF1- α were found to be the top four choices for different tissues, whereas TUB was not found to favor qRT-PCR normalization in these tissues. Three stable reference genes are recommended for the normalization of qRT-PCR data in R. molle . Furthermore, the expression profiles of RmPSY (phytoene synthase) and RmPDS (phytoene dehydrogenase) were assessed using EF1- α, 18S , ACT5 , RPL3 , and their combination as internals. Similar trends were found, but these trends varied when the least stable reference gene TUB was used. The results further prove that it is necessary to validate the stability of reference genes prior to their use for normalization under different experimental conditions. This study provides useful information for reliable qRT-PCR data normalization in gene studies of R. molle .

  17. Selection of Reliable Reference Genes for Gene Expression Studies on Rhododendron molle G. Don

    Directory of Open Access Journals (Sweden)

    Zheng Xiao

    2016-10-01

    Full Text Available The quantitative real-time polymerase chain reaction (qRT-PCR approach has become a widely used method to analyze expression patterns of target genes. The selection of an optimal reference gene is a prerequisite for the accurate normalization of gene expression in qRT-PCR. The present study constitutes the first systematic evaluation of potential reference genes in Rhododendron molle G. Don. Eleven candidate reference genes in different tissues and flowers at different developmental stages of R. molle were assessed using the following three software packages: GeNorm, NormFinder and BestKeeper. The results showed that EF1-α (elongation factor 1-alpha, 18S (18s ribosomal RNA and RPL3 (ribosomal protein L3 were the most stable reference genes in developing rhododendron flowers and, thus, in all of the tested samples, while tublin (TUB was the least stable. ACT5 (actin, RPL3, 18S and EF1-α were found to be the top four choices for different tissues, whereas TUB was not found to favor qRT-PCR normalization in these tissues. Three stable reference genes are recommended for the normalization of qRT-PCR data in R. molle. Furthermore, the expression profiles of RmPSY (phytoene synthase and RmPDS (phytoene dehydrogenase were assessed using EF1-α, 18S, ACT5, and RPL3 and their combination as internals. Similar trends were found, but these trends varied when the least stable reference gene TUB was used. The results further prove that it is necessary to validate the stability of reference genes prior to their use for normalization under different experimental conditions. This study provides useful information for reliable qRT-PCR data normalization in gene studies of R. molle.

  18. Rheum australe D. Don: a review of its botany, ethnobotany, phytochemistry and pharmacology.

    Science.gov (United States)

    Rokaya, Maan Bahadur; Münzbergová, Zuzana; Timsina, Binu; Bhattarai, Krishna Ram

    2012-06-14

    Rheum australe D. Don (Polygonaceae) has been commonly used in traditional medicine for a wide range of ailments related to the circulatory, digestive, endocrine, respiratory and skeletal systems as well as to infectious diseases. To provide the up-to-date information that is available on the botany, traditional uses, phytochemistry, pharmacology and toxicology of Rheum australe. Additionally, to highlight the possible uses of this species to treat different diseases and to provide a basis for future research. The present review covers the literature available from 1980 to 2011. The information was collected from scientific journals, books, theses and reports via a library and electronic search (Google Scholar, Web of Science and ScienceDirect). Ethnomedical uses of Rheum australe have been recorded from China, India, Nepal and Pakistan for 57 different types of ailments. The phytochemical studies have shown the presence of many secondary metabolites belonging to anthraquinones, stilbenes, anthrones, oxantrone ethers and esters, chromones, flavonoids, carbohydrate, lignans, phenols and sterols. Crude extracts and isolated compounds from Rheum australe show a wide spectrum of pharmacological activities, such as antidiabetic, anti-inflammatory, antifungal, antimicrobial, antioxidant, anticancer, hepatoprotective and immune-enhancing activities, as well as a usefulness for improving renal function. Rheum australe has been widely used source of medicine for years without any adverse effects. Many studies have provided evidence for various traditional uses. However, there is a need for additional studies of the isolated compounds to validate the traditional uses in human models. The present review on the botany, traditional uses, phytochemistry and toxicity has provided preliminary information for further studies and commercial exploitations of the plant. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  19. A neural model for transient identification in dynamic processes with 'don't know' response

    Energy Technology Data Exchange (ETDEWEB)

    Mol, Antonio C. de A. E-mail: mol@ien.gov.br; Martinez, Aquilino S. E-mail: aquilino@lmp.ufrj.br; Schirru, Roberto E-mail: schirru@lmp.ufrj.br

    2003-09-01

    This work presents an approach for neural network based transient identification which allows either dynamic identification or a 'don't know' response. The approach uses two 'jump' multilayer neural networks (NN) trained with the backpropagation algorithm. The 'jump' network is used because it is useful to dealing with very complex patterns, which is the case of the space of the state variables during some abnormal events. The first one is responsible for the dynamic identification. This NN uses, as input, a short set (in a moving time window) of recent measurements of each variable avoiding the necessity of using starting events. The other one is used to validate the instantaneous identification (from the first net) through the validation of each variable. This net is responsible for allowing the system to provide a 'don't know' response. In order to validate the method, a Nuclear Power Plant (NPP) transient identification problem comprising 15 postulated accidents, simulated for a pressurized water reactor (PWR), was proposed in the validation process it has been considered noisy data in order to evaluate the method robustness. Obtained results reveal the ability of the method in dealing with both dynamic identification of transients and correct 'don't know' response. Another important point studied in this work is that the system has shown to be independent of a trigger signal which indicates the beginning of the transient, thus making it robust in relation to this limitation.

  20. Autoridad y memoria entre los killakas. Las estrategias discursivas de don Juan Colque Guarache en el sur andino (Siglo XVI)

    OpenAIRE

    Graña, Mario Julio

    2014-01-01

    Entre 1575 y 1577, don Juan Colque Guarache, cacique principal de las etnias killaka, asanaque, sivaroyo,haracapi y uruquilla del sur del lago Poopó, actual Oruro (Bolivia)eleva a consideración de las autoridades españolas una serie de "Probanzasde Méritos y Servicios" de sus antepasados. Esta fuente permite explorar la narración de la historia de un linaje indígena, a la luz de las estrategias discursivas empleadas por las autoridades étnicas dentro del contexto colonial.En este sentido, se ...

  1. Literatura consolatoria en torno a la muerte del príncipe don Juán

    Directory of Open Access Journals (Sweden)

    Jacobo SANZ HERMIDA

    2009-12-01

    Full Text Available Se lamentaba Juan del Encina haciéndose eco del dolor que asoló a España tras la muerte del príncipe don Juan, primogénito de los Reyes Católicos: «Fortuna nos traxo tal pena penosa/ que ágenos nos hizo de toda holganca./ Secóse la flor de nuestra esperanca,/ gran fruto esperando de planta graciosa:/ nacieron espinas; secóse la rosa;/ secóse la flor; nacieron abrojos;/ nacieron fatigas, nacieron enojos./ Murió nuestro Príncipe, joya preciosa».

  2. Tempo e percezione in The Body Artist di Don DeLillo e Ghost Trio di Samuel Beckett

    Directory of Open Access Journals (Sweden)

    Davide Barbuscia

    2013-03-01

    Full Text Available This essay provides a critical analysis of Don DeLillo’s novel The Body Artist and Samuel Beckett’s work for television Ghost Trio. In particular it analyses the representation of time and its perception in both these works, highlighting some shared aesthetic modalities such as their attempt to depict duration through a poetics of slow motion. The essay also foregrounds how both these works give narrative form to Merleau-Ponty’s understanding of ‘time as its perception’.

  3. ¡Deje hablar! La transferencia en "Las desdichas de Cardenio" de Don Quijote de la Mancha

    Directory of Open Access Journals (Sweden)

    Oswaldo Ortegón

    2012-02-01

    Full Text Available Entre los distintos estudios que relacionan la literatura de creación con el psicoanálisis clínico y su comprensión metapsicológica, se destaca el papel ilustrador del arte y la literatura en la explicación del pensamiento psicoanalítico. Este trabajo discute el concepto fundamental de la transferencia, teniendo como referente la locura de Cardenio, un personaje de Don Quijote de la Mancha. Varios elementos técnicos del quehacer psicoanalítico florecen alrededor del estudio de esta idea.

  4. LA PARODIA ENTRE LA FICCIÓN YLA REALIDAD EN EL INGENIOSO HIDALGO DON QUIJOTE DE LA MANCHA

    OpenAIRE

    Nora González Gandiaga

    2005-01-01

    En este trabajo se aborda la problemática de la ficción y de la realidad intermediada por la operación paródica en El Ingenioso Hidalgo don Quijote de La Mancha de Miguel de Cervantes Saavedra. Se asedia el texto para ver cómo la parodia y la ironía son estrategias fundamentales para leer la concepción novelesca y cómo se permite al lector avieso adentrarse en la Poética cervantina, partiendo de los paratextos: prólogo, sonetos iniciales antes de adentrarnos en el cuerpo de la novela para lue...

  5. Program of chemical research organic moderators and coolants in regard with the project of the Spanish DON-Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Fernandez Cellini, R

    1961-07-01

    In order to select the most suitable mixtures for cooling the Reactor DON, in project, within the group of polyphenyl compounds, which at present time prevails in organic nuclear power reactor philosophy, the following subjects are going to be studied: 1. Static and dynamic experiences of thermal and radiolytic stability of commercial polyphenyl mixtures. 2. Studies on purification of the damaged coolant and search for possible applications of the residual polymers. 3. Analytical control and measurement of the physical constants of the polyphenyl mixtures. (Author)

  6. Density determination in Pino Radiata (D.Don) samples using 59.5 keV gamma radiation attenuation

    International Nuclear Information System (INIS)

    Dinator, Maria I.; Morales, Jose R.; Aliaga, Nelson; Karsulovic, Jose T.; Sanchez, Jaime; Leon, Adolfo

    1996-01-01

    A non destructive method to determine wood samples density is presented. The photon mass attenuation coefficient in samples of Pino radiata (D.Don) was measured at 59.5 keV with a radioactive source of Am-241. The value of 0.192 ± 0.002 cm 2 /g was obtained with a gamma spectroscopy system and later used on the determination of the mass density in sixteen samples of the same species. Comparison of these results with those of gravimetric method through a linear regression showed a slope of 1.001 and a correlation factor of 0.94. (author)

  7. Program of chemical research on organic moderators and coolants in regard with the project of the Spanish DON-Reactor

    International Nuclear Information System (INIS)

    Fernandez Cellini, R.

    1961-01-01

    In order to select the most suitable mixtures for cooling the Reactor DON, in project, within the group of polyphenyl compounds, which at present time prevails in organic nuclear power reactor philosophy, the following subjects are going to be studied: 1. Static and dynamic experiences of thermal and radiolytic stability of commercial polyphenyl mixtures. 2. Studies on purification of the damaged coolant and search for possible applications of the residual polymers. 3. Analytical control and measurement of the physical constants of the polyphenyl mixtures. (Author)

  8. Colonel Don Benito Machado. A National Guards commandant on the southern frontier of Buenos Aires [1852-1880] El coronel Don Benito Machado. Un comandante de Guardias Nacionales en la frontera sur bonaerense [1852-1880

    Directory of Open Access Journals (Sweden)

    Leonardo Canciani

    2012-01-01

    Full Text Available In this work, we will analyze the National Guard regiments and the role played by their commandants during the process of national organization on the southern frontier of Buenos Aires, from the case study of coronel don José Benito Machado. First of all, our objective will be describe the specific characteristics that adopted the National Guards in the societies of the southern frontier of the province of Buenos Aires. And then, to analyze the mechanisms developed by Benito Machado to build the power bases in the region that enabled the consolidation of its leadershipEn el presente trabajo, analizamos los regimientos de Guardias Nacionales y las funciones que desempeñaron sus comandantes durante el proceso de organización nacional en la frontera sur bonaerense, desde el estudio de caso del coronel don José Benito Machado. En primer lugar, repasamos las características específicas que adoptaron las Guardias Nacionales en las sociedades de la frontera sur de la provincia de Buenos Aires; mientras que, en segundo lugar, analizamos los diversos mecanismos desarrollados por Benito Machado para construir las bases de poder en la región que posibilitaron el afianzamiento de su liderazgo

  9. Las representaciones de Don Gaspar de Haro y Guzmán, VII Marqués del Carpio: retratos, alegorías y emblemas

    Directory of Open Access Journals (Sweden)

    López-Fanjul y Díez del Corral, María

    2013-12-01

    Full Text Available The author studies various portraits of Don Gaspar de Haro y Guzmán, 7th Marquis of Carpio, and analyses the strong links that they had with his interest in drawing, emblems, allegories, and the search for fame through books.Este artículo está dedicado a estudiar una serie de retratos de Don Gaspar de Haro y Guzmán, VII Marqués del Carpio, especialmente importantes por su relación con el dibujo, las alegorías, los emblemas y la búsqueda de la fama a través de los libros.

  10. Rediscovering Don Swanson: The Past, Present and Future of Literature-based Discovery

    Directory of Open Access Journals (Sweden)

    Neil R. Smalheiser

    2017-12-01

    Full Text Available Purpose: The late Don R. Swanson was well appreciated during his lifetime as Dean of the Graduate Library School at University of Chicago, as winner of the American Society for Information Science Award of Merit for 2000, and as author of many seminal articles. In this informal essay, I will give my personal perspective on Don’s contributions to science, and outline some current and future directions in literature-based discovery that are rooted in concepts that he developed. Design/methodology/approach: Personal recollections and literature review. Findings: The Swanson A-B-C model of literature-based discovery has been successfully used by laboratory investigators analyzing their findings and hypotheses. It continues to be a fertile area of research in a wide range of application areas including text mining, drug repurposing, studies of scientific innovation, knowledge discovery in databases, and bioinformatics. Recently, additional modes of discovery that do not follow the A-B-C model have also been proposed and explored (e.g. so-called storytelling, gaps, analogies, link prediction, negative consensus, outliers, and revival of neglected or discarded research questions. Research limitations: This paper reflects the opinions of the author and is not a comprehensive nor technically based review of literature-based discovery. Practical implications: The general scientific public is still not aware of the availability of tools for literature-based discovery. Our Arrowsmith project site maintains a suite of discovery tools that are free and open to the public (http://arrowsmith.psych.uic.edu, as does BITOLA which is maintained by Dmitar Hristovski (http:// http://ibmi.mf.uni-lj.si/bitola, and Epiphanet which is maintained by Trevor Cohen (http://epiphanet.uth.tmc.edu/. Bringing user-friendly tools to the public should be a high priority, since even more than advancing basic research in informatics, it is vital that we ensure that scientists

  11. “El asesinato del Chantre Don Ventura Ferrer. Clérigos y bandos en la Seo valentina seiscentista”

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    Callado Estela, Emilio

    2014-06-01

    Full Text Available The cathedral clergy did not remain aloof from the factions that drew together a major part of the valencian society during the XVII century. A good example is the case of the precentor Don Ventura Ferrer, who led one of the cathedral sections and who, supported by the Vallterra family, sought the control of the first church of the kingdom. On the opposite side was the group of canons represented by the admiral of Aragón, head of the opposing supporters and liable for the precentor’s murder in 1661. This event revealed the overlapping of the ecclesiastic world and the phenomenon of banditry.El clero de la Seo no fue ajeno a las bandositats que aglutinaron a buena parte de la sociedad valenciana durante el siglo XVII. Lo demuestra el caso del chantre don Ventura Ferrer, líder de una de las facciones catedralicias que, con el apoyo externo del bando de los Vallterra, luchaba por el control de la primera iglesia del reino. Frente a él, el grupo de canónigos patrocinado por el Almirante de Aragón, a la cabeza de la parcialidad contraria y responsable último del asesinato del chantre en 1661, suceso este que pondría al descubierto la imbricación entre el mundo eclesiástico y el fenómeno del bandolerismo.

  12. UMTRA water sampling technical (peer) review: Responses to observations, comments, and recommendations submitted by Don Messinger (Roy F. Weston, Inc.)

    International Nuclear Information System (INIS)

    1993-08-01

    An independent technical review (peer review) was conducted during the period of September 15--17, 1992. The review was conducted by C. Warren Ankerberg (Geraghty and Miller, Inc., Tampa, Florida) and Don Messinger (Roy F. Weston, Inc., West Chester, Pennsylvania). The review was held at Jacobs Engineering in Albuquerque, New Mexico, and at the Shiprock, New Mexico, site. The peer review included a review of written documentation [water sampling standard operating procedures (SOP)], an inspection of technical reports and other deliverables, a review of staff qualifications and training, and a field visit to evaluate the compliance of field procedures with SOPS. Upon completion of the peer review, each reviewer independently prepared a report of findings from the review. The reports listed findings and recommended actions. This document responds to the observations, comments, and recommendations submitted by Don Messinger following his review. The format of this document is to present the findings and recommendations verbatim from Mr. Messinger's report, followed by responses from the UMTRA Project staff. Included in the responses from the UMTRA Project staff are recommended changes in SOPs and strategies for implementing the charges

  13. Tsunami survivors' perspectives on vulnerability and vulnerability reduction: evidence from Koh Phi Phi Don and Khao Lak, Thailand.

    Science.gov (United States)

    Steckley, Marylynn; Doberstein, Brent

    2011-07-01

    This paper presents the results of primary research with 40 survivors of the 2004 Indian Ocean tsunami in two communities: Khao Lak (n=20) and Koh Phi Phi Don (n=20), Thailand. It traces tsunami survivors' perceptions of vulnerability, determines whether residents felt that the tsunami affected different communities differently, identifies the populations and sub-community groups that survivors distinguished as being more vulnerable than others, highlights community-generated ideas about vulnerability reduction, and pinpoints a range of additional vulnerability reduction actions. Tsunami survivors most consistently identified the 'most vulnerable' community sub-populations as women, children, the elderly, foreigners, and the poor. In Khao Lak, however, respondents added 'Burmese migrants' to this list, whereas in Koh Phi Phi Don, they added 'Thai Muslims'. Results suggest that the two case study communities, both small, coastal, tourism-dominated communities no more than 100 kilometres apart, have differing vulnerable sub-groups and environmental vulnerabilities, requiring different post-disaster vulnerability reduction efforts. © 2011 The Author(s). Disasters © Overseas Development Institute, 2011.

  14. Le don après un décès d'origine cardiocirculatoire au Canada

    Science.gov (United States)

    Shemie, Sam D.; Baker, Andrew J.; Knoll, Greg; Wall, William; Rocker, Graeme; Howes, Daniel; Davidson, Janet; Pagliarello, Joe; Chambers-Evans, Jane; Cockfield, Sandra; Farrell, Catherine; Glannon, Walter; Gourlay, William; Grant, David; Langevin, Stéphan; Wheelock, Brian; Young, Kimberly; Dossetor, John

    2006-01-01

    Résumé Ces recommandations sont le fruit d'un processus multidisciplinaire national ayant duré un an et visant à déterminer si et comment l'on pourrait procéder au don d'organes après un décès d'origine cardiocirculatoire («don après le décès cardiocirculatoire», ou DDC) au Canada. Le forum national organisé en février 2005 a permis aux participants de discuter et d'élaborer des recommandations sur les principes, interventions et pratiques se rapportant au DDC. Les aspects éthiques et juridiques ont été abordés dans les discussions. À la fin du Forum, la majorité des participants ont été favorables à l'implantation de programmes de DDC au Canada. Les participants du Forum ont également convenu qu'il fallait formuler et prôner des valeurs fondamentales pour orienter l'élaboration de programmes et de protocoles basés sur le cadre médical, éthique et juridique établi lors de cette réunion. Même si la possibilité d'un don d'organes et de tissus doit faire partie intégrante des soins de fin de vie, il faut insister sur le fait que le devoir de diligence envers les patients mourants et leurs familles doit demeurer la priorité des équipes soignantes. La complexité et les répercussions profondes du décès sont reconnues et doivent être respectées, de même que les différences personnelles, ethnoculturelles et religieuses face à la mort et au don d'organes. Les décisions d'arrêter le traitement de maintien des fonctions vitales, la prise en charge des derniers moments de la vie et le diagnostic de décès selon des critères cardiocirculatoires doivent être distincts et indépendants des processus de don et transplantation. Ce rapport contient des recommandations destinées aux gestionnaires de program, aux autorités sanitaires régionales et aux instances appelés à élaborer les protocoles de DDC. Les programmes doivent être conçus en fonction des éléments suivants : direction et planification locales, éducation et

  15. Iconographic analysis of the covers of school editions of Don Quijote between the Second Republic and Francoism

    Directory of Open Access Journals (Sweden)

    Luis Rodrigo Martín

    2016-11-01

    Full Text Available Don Quixote is the most recognized work of Spanish and universal literature, and teaching adaptations in schools are very important for children to understand their reading. Compulsory reading of the work during the period between the Second Republic and the Franco regime caused many school adaptations to suit their classroom teaching. This study focused on the graphic elements of the work from a communicative and iconographic perspective, allows through content analysis of a cataloged and representative sample of the covers of school adaptations, verify that the hard political interventionism that suffered the work according antagonistic dominant ideologies did not influence their design, because these spaces were not ideologically charged, despite being the first element of commercial persuasion of the book and its role motivate reading. Analytical data along with historical explain the existence of a commercial image of Quixote free of ideological connotations (on the cover, from his iconographic path, which we have not found significant differences from the two dominant ideologies. However, the politicization of the work contributed to Don Quixote became the national hero of children and adults and a universal benchmark of behavior full of great ethical and moral values.

  16. An intimate understanding of place: Charles Sauriol and Toronto’s Don River Valley, 1927-1989.

    Science.gov (United States)

    Bonnell, Jennifer

    2011-01-01

    Every summer from 1927 to 1968, Toronto conservationist Charles Sauriol and his family moved from their city home to a rustic cottage just a few kilometres away, within the urban wilderness of Toronto’s Don River Valley. In his years as a cottager, Sauriol saw the valley change from a picturesque setting of rural farms and woodlands to an increasingly threatened corridor of urban green space. His intimate familiarity with the valley led to a lifelong quest to protect it. This paper explores the history of conservation in the Don River Valley through Sauriol’s experiences. Changes in the approaches to protecting urban nature, I argue, are reflected in Sauriol’s personal experience – the strategies he employed, the language he used, and the losses he suffered as a result of urban planning policies. Over the course of Sauriol’s career as a conservationist, from the 1940s to the 1990s, the river increasingly became a symbol of urban health – specifically, the health of the relationship between urban residents and the natural environment upon which they depend. Drawing from a rich range of sources, including diary entries, published memoirs, and unpublished manuscripts and correspondence, this paper reflects upon the ways that biography can inform histories of place and better our understanding of individual responses to changing landscapes.

  17. A possibilistic approach for transient identification with 'don't know' response capability optimized by genetic algorithm

    International Nuclear Information System (INIS)

    Almeida, Jose Carlos S. de; Schirru, Roberto; Pereira, Claudio M.N.A.; Universidade Federal, Rio de Janeiro, RJ

    2002-01-01

    This work describes a possibilistic approach for transient identification based on the minimum centroids set method, proposed in previous work, optimized by genetic algorithm. The idea behind this method is to split the complex classification problem into small and simple ones, so that the performance in the classification can be increased. In order to accomplish that, a genetic algorithm is used to learn, from realistic simulated data, the optimized time partitions, which the robustness and correctness in the classification are maximized. The use of a possibilistic classification approach propitiates natural and consistent classification rules, leading naturally to a good heuristic to handle the 'don't know 'response, in case of unrecognized transient, which is fairly desirable in transient classification systems where safety is critical. Application of the proposed approach to a nuclear transient indentification problem reveals good capability of the genetic algorithm in learning optimized possibilistic classification rules for efficient diagnosis including 'don't know' response. Obtained results are shown and commented. (author)

  18. Don Miguel Samper: la ética y el espíritu de empresa en el siglo XIX

    Directory of Open Access Journals (Sweden)

    Luis Ernesto Romero Ortíz

    1988-04-01

    Full Text Available RESUMEN El presente artículo relaciona el concepto de ética y moral con la actividad empresarial a través del análisis que se hace del pensamiento de Don Miguel Samper Agudelo, empresario exitoso y uno de los mayores ideólogos liberales de la segunda mitad del siglo XIX. Con una visión weberiana sobre el comportamiento empresarial, se busca destacar el papel que los valores tienen sobre la iniciativa empresarial tomado como base el conocido ensayo “La miseria en Bogotá”, escrito por don Miguel Samper, en el cual de manera implícita y explícita  las más de las veces, el autor deja expuesta su visión acerca de la moral como determinante en el desarrollo económico de una sociedad. Se indican los aspectos formadores de la ética empresarial que según Miguel Samper aportó la cultura eclesiástica, las instituciones educativas  y la cultura política imperante  en la segunda mitad del siglo XIX en  Colombia.

  19. The Field Guide to ADHD: What They Don't Want You to Know. Psychiatry--Theory, Applications and Treatments

    Science.gov (United States)

    Harding, Blake

    2017-01-01

    In "The Field Guide to ADHD: What They Don't Want You to Know," Harding confronts with unusual candor and painstaking effort one of the most alarming and perilous crises of our time: ADHD. In confronting this crisis, Harding forces us to reconsider the assumptions underlying ADHD and how we think about medical diagnoses, disability,…

  20. Uudised : Don Juan jõuab Estonia lavale. VII Rudolf Tobiase päevad Hiiumaal. Esineb Laine Leichteri koolkond / Liina Teder

    Index Scriptorium Estoniae

    Teder, Liina

    1999-01-01

    3.juunil Estonias esietenduvast Mozarti ooperist "Don Giovanni". 28.-29.05 toimuvatest VII R. Tobiase päevadest, mis on pühendatud helilooja 126. sünniaastapäevale. 3.06 Mustpeade Majas toimuvast L. Leichteri juubelikontserdist

  1. Short-term and long-term effects of tannins on nitrogen mineralisation and litter decomposition in kauri (Agathis australis (D. Don) Lindl.) forests

    NARCIS (Netherlands)

    Verkaik, E.; Jongkind, A.G.; Berendse, F.

    2006-01-01

    Kauri (Agathis australis (D. Don) Lindl.) occurs naturally in the warm temperate forest of northern New Zealand where it grows mixed with angiosperm tree species. Below mature kauri trees thick organic layers develop in which large amounts of nitrogen are accumulated. This nitrogen seems to be

  2. Muusikamaailm : Praemium Imperiale kätteandmine. Vanamuusika päevad Hernes. Uus ooper Don Quijotest. Soome muusikud Münchenis / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    1999-01-01

    Jaapani kunstide auhinna "Praemium Imperiale" laureaatidest. Lääne-Saksa Raadio festivalist "Herne", tänavu pealkirja all "Spiel auf, Europa!". C. Halffteri uudisooper "Don Quijote" tuleb maailmaesiettekandele Madridis 2000. a. veebruaris. Soome muusikute kontsertidest sügishooajal Baierimaal ja Münchenis

  3. Brain delivery of the glutamine antagonist 6-Diazo-5-oxo-L-norleucine (DON) via prodrug approach: a potential treatment for HIV-associated neurocognitive disorders (HAND)

    Czech Academy of Sciences Publication Activity Database

    Nedelcovych, M.; Kim, B. H.; Rais, R.; Jančařík, Andrej; Tenora, Lukáš; Alt, J.; Kelschenbach, J.; Majer, Pavel; Volsky, D.; Slusher, B.

    2016-01-01

    Roč. 22, Suppl 1 (2016), S57-S58 ISSN 1355-0284. [International Symposium on NeuroVirology /14./. 25.10.2016-28.10.2016, Toronto] Institutional support: RVO:61388963 Keywords : glutamate * DON * HAND treatment Subject RIV: CC - Organic Chemistry

  4. Helping Teams Succeed: An Essay Review of "Groups That Work (and Those That Don't): Creating Conditions for Effective Teamwork."

    Science.gov (United States)

    Kain, Daniel L.

    1993-01-01

    Teams are incompatible with the scientific management philosophy underlying traditional curricular and organizational theory. This article examines J. R. Hackman's book "Groups That Work (and Those That Don't): Creating Conditions for Effective Teamwork" (1990), as it illuminates the experience of teaching on a middle school…

  5. Don Quijote de la Mancha, de Rafael Gil: una adaptación literaria del cine español en las conmemoraciones cervantinas de 1947

    Directory of Open Access Journals (Sweden)

    María del Mar Mañas Martínez

    2006-12-01

    – Differences caused by ideological reasons. The differences that try to adapt the Cervantes text to the ideological requirements of the “Franquismo”. We can find: the idealization and glorification of Don Quixote, the disappearance of scatological elements, the disappearance or modification of subversive elements (for example the ones related to the Muslim universe, and the simple and plain ideological manipulation.

  6. Transmission and Preservation of music of the Laos Vieng Ethnics Group at Tumbol Don kha, U-thong Distric SuphanBuri province

    Directory of Open Access Journals (Sweden)

    Nuttapot Pocharoen

    2016-10-01

    Full Text Available Music Vieng, Laos, Vientiane, Lao ethnic group identity. And this is something that represents the cultural and traditional beliefs from the past, which is very important and plays a role in Vientiane, Lao ethnic group. Today This research aims to 1. To study the music of ethnic Lao Wiang Thong, Suphan Buri Province Don Kha 2. To study the musical heritage and preservation of ethnic groups in Laos Vieng Thong, Suphan Buri Province Don Kha. The results showed that the music of ethnic Lao Wiang Thong, Suphan Buri Province Don Kha. Originally a folk music as well as the East. Originally, Canada is the main instrument. Vientiane, Laos ethnic group influenced society. And culture outside to inside. The group of friends and was popular with the younger generation. Lack of support from local organizations People who know less. Make music, ethnic Vieng, Laos began to fade with time. ceremony, a ritual is believed the disease. Similar to the medium by a worship of ancestors. Conservation and musical heritage of ethnic groups in Laos Don Kha Vieng Thong, Suphan Buri. Are passed down from generation to generation through teaching, saying to each other in kinship. There are performances at various events Playing music in various applications And shows for visitors to watch.

  7. Living in a simulacrum: how TV and the supermarket redefines reality in Don DeLillo’s White Noise

    Directory of Open Access Journals (Sweden)

    Ghashmari, Ahmad

    2010-07-01

    Full Text Available This paper examines the impact of simulation, hyperreality, and consumerism on Don Delillo's novel "White Noise". It discusses how the novel pictures technology and mass media as an empire of signs and codes that erase or implode meaning. TV, radio reports and tidbits, and medical imaging devices are intertwined with many aspects of people's lives in this late capitalist culture. Futhermore, the paper will shed some light on the issue of hyperreality which is generated by simulations. We will see how this new type of reality becomes more real than reality itself. Then, the influence of the supermarket and the emergence of consumer culture will be discussed. We will see how production and consumption have gained a new different meaning in this new "superficial" society and how it reshapes people's undestanding and interaction with reality.

  8. Cedrin identified from Cedrus deodara (Roxb.) G. Don protects PC12 cells against neurotoxicity induced by Aβ1-42.

    Science.gov (United States)

    Zhao, Zhiwei; Dong, Zhanfei; Ming, Jie; Liu, Yan

    2018-06-01

    Alzheimer's disease is a severe neurodegenerative disease affecting elder worldwide and closely related to the neurotoxicity induced by amyloid β. To find efficient therapeutics, we have investigated the protective effects of cedrin from Cedrus deodara (Roxb.) G. Don on PC12 cells against the neurotoxicity induced by amyloid β 1-42 . The results have shown the viability of PC12 cells injured by amyloid β 1-42 can be improved by cedrin. Cedrin can reduce reacrive oxygen species overproduction, increase the activity of superoxide dismutase and decrease malondialdehyde content. Meanwhile, the loss of mitochondrial membrane potential and mitochondrial permeability transition pore opening in PC12 cells, and elevated Caspase-3 activity, downregulated Bcl-2 and upregulated Bax are meliorated. These results demonstrate the protective effect of cedrin is related to the inhibition of oxidative stress, improvement of mitochondrial dysfunction and suppression of apoptosis. This investigation gives evidences for the application of cedrin in practice and further investigation in vivo.

  9. Celebrations III and IV Centenary of Don Quixote in Spanish America through the Spanish press from 1905 to 2005

    Directory of Open Access Journals (Sweden)

    María Ángeles Chaparro Domínguez

    2012-12-01

    Full Text Available This article analyzes the coverage that the Spanish press provided to Spanish American celebrations for the Third and Fourth Centenary of the publication of the first part of Don Quixote, events that took place in 1905 and 2005, respectively. By the study of a total of twenty-one newspapers, which include El Imparcial, El Liberal and La Correspondencia de España, of the first period, and El País, El Mundo and La Vanguardia of the second, we will find out how they lived both centenaries in Spanish America, how important were these tributes in the press and, furthermore, we will know the concrete symbolic meaning that the popular Spanish nobleman acquired in either period.

  10. Biotransformation of artemisinin using cell suspension cultures of Catharanthus roseus (L.) G.Don and Lavandula officinalis L.

    Science.gov (United States)

    Patel, Suman; Gaur, Rashmi; Verma, Priyanka; Bhakuni, Rajendra S; Mathur, Archana

    2010-08-01

    Artemisinin, an antimalarial compound, at 5 mg/40 ml, was transformed by cell suspension cultures of Catharanthus roseus (L.) G.Don and Lavandula officinalis L. into deoxyartemisinin with yields >78% (3.93 mg deoxyartemisinin from 5 mg artemisinin). Maximum conversion (78.6 and 78%) occurred after 6 and 7 days of adding artemisinin to 20 and 9 days old cultures of C. roseus and L. officinalis, respectively. The procedure was scaled up by and 500 mg artemisinin was transformed into 390 mg deoxyartemisinin. Addition of artemisinin at the beginning of the culture cycle resulted in >50% reduction in dry biomass production with no bioconversion. Conversion of artemisinin occurred intracellularly followed by leaching of the product into the medium.

  11. A propósito de los dibujos inéditos del Instituto Valencia de Don Juan

    Directory of Open Access Journals (Sweden)

    Ocaña Martínez, José Antonio

    2001-06-01

    Full Text Available El Instituto Valencia de Don Juan, constituido notarialmente en 1916 conforme a las ideas de Guillermo Joaquín de Osma y Scull (La Habana, 1853-Madrid, 1922, casado con la última condesa de dicho título, Adelaida Crooke y Guzman (Madrid, 1863-París, 1918, guarda, en un reformado palacete de la calle Fortuny de Madrid, importantes colecciones de pinturas, esculturas, tapices, bordados, armas, azulejos, loza, alfarería, azabaches, monedas, muebles, libros y documentos, que el matrimonio logró reunir, provenientes de sus antepasados y adquiridos por ellos. Entre tan valiosos fondos casi pasan desapercibidos los veintiocho dibujos, que hemos catalogado recientemente, los cuales no pueden considerarse una colección sino un conjunto de piezas que llegaron aleatoriamente a la Institución, la mayoría de procedencia hoy desconocida, realizados entre principios de los siglos XVI y XX.…

  12. Don't end up in the fields: identity construction among Mexican adolescent immigrants, their parents, and sociocontextual processes.

    Science.gov (United States)

    Maciel, Jose A; Knudson-Martin, Carmen

    2014-10-01

    This grounded theory study of 16 Mexican immigrant adolescents and 20 of their parents examines how they construct relational identities within their families, at school, with friends, and in the larger society. Results focus on a core identity bind faced by the adolescents: immigration messages from parents that say, "don't be like me" and the societal message, "you're not like us." Response to this bind was guided by two contrasting sets of identity narratives: Empowering narratives invited an intentional approach to school and life choices. Restricting narratives maintained an ambivalent approach to school and life choices. Resolution of the identity bind was a collective, ongoing process that has implications for Mexican immigrant families and the professionals who work with them. © 2013 American Association for Marriage and Family Therapy.

  13. NASA aircraft technician Don Herman completes placement of the first official U.S. Centennial of Fli

    Science.gov (United States)

    2002-01-01

    NASA aircraft technician Don Herman completes placement of the first official U.S. Centennial of Flight Commission logo on an aircraft. The honored recipient is NASA Dryden Flight Research Center's Active Aeroelastic Wing (AAW) F/A-18 research aircraft, which is poised to begin wing-warping research flights harkening back to the Wright brothers. The Centennial of Flight Commission was created by the U.S.Congress in 1999 to serve as a national and international source of information about activities to commemorate the centennial of the Wright Brothers' first powered flight on the sands of Kitty Hawk, North Carolina, on December 17, 1903. Centennial activities are scheduled for 2003 in both North Carolina and Dayton, Ohio, home of the Wrights. In addition to these celebrations, numerous historical and educational projects are anticipated on the subject of aviation and aeronautics that will be an important legacy of the centennial of powered flight.

  14. MADERA DE COMPRESIÓN EN PINUS RADIATA D. DON: I, CARACTERÍSTICAS ANATÓMICAS

    OpenAIRE

    Diaz-vaz,J.E; Fernandez,A; Valenzuela,L; Torres,M

    2007-01-01

    Se caracterizó la madera de compresión en 10 árboles de Pinus radiata D.Don con inclinaciones menores a 10 º en dos sitios.          Los diámetros de traqueidas de los árboles del sitio Arena húmeda resultaron estadísticamente mayores que los del sitio Arcilla; pero no resultaron diferentes al comparar madera juvenil y madura o al compara madera de compresión con madera opuesta.          Diferencias significativas se determinaron en el largo de traqueida entre sitios (Arena húmeda-Arcilla), t...

  15. Influence of environmental factors on composition of volatile constituents and biological activity of Helichrysum italicum (Roth) Don (Asteraceae).

    Science.gov (United States)

    Tundis, R; Statti, G A; Conforti, F; Bianchi, A; Agrimonti, C; Sacchetti, G; Muzzoli, M; Ballero, M; Menichini, F; Poli, F

    2005-06-01

    The biovariability of Helichrysum italicum (Roth) Don grown wild in Calabria and Sardinia (Italy) was reported. This species has been characterized through the detection, isolation and quantitative evaluation of chemical markers (alpha-terpinolene, trans-cariophyllene and neryl acetate) by GC and GC-MS. Antioxidant activity of the methanolic H. italicum extracts using DPPH and beta-carotene bleaching test showed that the Calabrian samples were more active than those from Sardinia. The antibacterial activity of all extracts evidenced the best performance on the Gram positive bacteria particularly on Micrococcus luteus. Moreover, antifungal activity of all extracts was also tested evidencing important results particularly on the phytopathogene fungus Pythium ultimum. In general, as regards the antifungal activity, the extracts from Sardinia were more active than those from Calabria. The phytochemical analysis and the biological activity data suggested a possible use of these plant matrices in alimentary, cosmetic and pharmaceutical fields.

  16. LA PARODIA ENTRE LA FICCIÓN YLA REALIDAD EN EL INGENIOSO HIDALGO DON QUIJOTE DE LA MANCHA

    Directory of Open Access Journals (Sweden)

    Nora González Gandiaga

    2005-11-01

    Full Text Available En este trabajo se aborda la problemática de la ficción y de la realidad intermediada por la operación paródica en El Ingenioso Hidalgo don Quijote de La Mancha de Miguel de Cervantes Saavedra. Se asedia el texto para ver cómo la parodia y la ironía son estrategias fundamentales para leer la concepción novelesca y cómo se permite al lector avieso adentrarse en la Poética cervantina, partiendo de los paratextos: prólogo, sonetos iniciales antes de adentrarnos en el cuerpo de la novela para luego calar en éste. En todo este cometido colaboran los narradores ficticios para "leer" la novela moderna que postula Cervantes en el libro e incluso se advierte que los distintos narradores dejan al descubierto la parodia y al mismo tiempo permiten un juego crítico-reflexivo en la materia textualThis paper examines the problematic of fiction and reality as mediated by parody in Cervantes’ Don Quijote de la Mancha. The approach to the text is meant to see how parody and irony become fundamental strategies to understand the novelistic concept, and how the perceptive reader is permitted to enter into the Cervantine poetic, starting from the paratexts: the Prologue; the opening sonnets, before getting into the core of the work discriminatingly. In all this procedure fictitious narrators collaborate in the reading of the modernistic novel which Cervantes postulated. It may also be noticed how the different narrators disclose the parodic while allowing a critical-reflexive play in the text

  17. Geological and environmental observations in the Sunchales Creek and Tonco River , Don Otto uranium mine, Salta Province

    International Nuclear Information System (INIS)

    Gorustovich, S.; Guidi, F.; Bárbaro, N.; Nievas, H.; Tomellini, G.

    2013-01-01

    Results of geological and environmental observations made by professionals of the Comisión Nacional de Energía Atómica (CNEA) down streams Don Otto uranium mine on the Sunchales creek, from Los Guanacos strait down to the Tonco river mouth, and from river mouth down to narrow pass named Salto Grande, are presented in this report. La Yesera, Las Curtiembres and Los Blanquitos Formations of the Pirgua Subgroup, and Lecho and Yacoraite Formations of the Balbuena Subgroup crops out in that area (Salta Group, Cretaceous- Middle Eocene). Water stream analyses have given uranium contents between 890 μg/L and 1,100 μg/L, and uranium in stream sediments between 4 μg/g and 14 μg/g; radimetric anomalias up to 1,500 c/s in discoloured facies of the Las Curtiembres Formation, and 2,000 c/s in dark pelitic sediments of the Yacoraite Formation. A new zone with uranium traces in Curtiembres Formation belonging to the Pirgua Subgroup has been identified in the Alemanía cretaceous basin, which is stratigraphically similar to Cajoncillo, Las Abritas and El Fraile deposits. Those traces in addition to the other ones localized in the upper third of the Yacoraite Formation would have been originated by the geochemical uranium anomalies in waters and stream sediments by uranium leaching of rocks. The geochemical uranium anomalies in water and sediments are not a consequence of the antropic activity of the uranium mining carried out in Don Otto mine (1961-1982). (authors) [es

  18. Le don en anamorphose ou la réécriture du monde. Configurations et enjeux de l’hospitalité dans le récit médiéval (XIIe-XIIIe siècles

    Directory of Open Access Journals (Sweden)

    Carlos Fonseca Clamote Carreto

    2009-05-01

    Full Text Available  « A la limite, le don comme don devrait ne pas apparaître comme don ni au donataire, ni au donateur […]. En ce sens, le don est l’impossible. Non pas impossible, mais la figure même de l’impossible. » J. Derrida, Donner le temps.« Biaz sire, fet il, bien vaingniez.Se o moi herbergiez daingniez,Vez l’ostel aparelliés »Chrétien de Troyes, Érec et Énide.Arthur ou la largesse infinieÀ une époque où, de Jean de Salisbury à Brunetto Latini, en passant par Jacques de Vitry ou Guillaume Le Clerc de ...

  19. Estrategias metodológicas para la interpretación y el análisis de la obra literaria El Ingenioso Hidalgo Don Quijote de la Mancha

    Directory of Open Access Journals (Sweden)

    Marlene Aguirre-Chaves

    2006-06-01

    • To propose a didactic unit to develop the multiple intelligencies in the literary study of the literary work of El Ingenioso Hidalgo Don Quijote de la Mancha. After analyzing the data, a series of methodological strategies to interpret and analyse the novel El Ingenioso Hidalgo Don Quijote de la Mancha, wich contributes to improve the teaching and learning process in the Spanish subject, in particular, to change the negative perception that the students have about reading the masterpiece of Miguel de Cervantes.

  20. Half a Century of Life Don Khutor: the Parish Chronicle of St. Panteleimon• s Church of Khutor Letovskiy, Stanitsa Kremenskaia, Ust`-Medveditskaya District, Troops of the Don Region (1873-1929

    Directory of Open Access Journals (Sweden)

    Ageev Evgenii, priest

    2016-12-01

    Full Text Available The article puts forward into scientific circulation a valuable source on the history of the parish life of the late 19th — early 20th century on the Don — the parish chronicle found in one of the investigations of the repressed clergy. This chronicle is unique high temporal coverage, from 1873 to 1929, it includes the years of revolution, Civil war on the Don and the first post-revolutionary decade. The author gives a brief overview of the history of the chronicle, the characteristics of its six authors — rural priests. The first thirty years were marked by the construction and decoration of the church and the absence of conflict. The early twentieth century was marked by the confl icts of the parishioners with the clergy. In the chronicle it was described the hardships of the lives of ordinary Cossacks, the scourge of Civil war, the famine of the early 1920s. In the postwar years there has been growing discontent of the parishioners by the activities of the Soviet government: tax policy, anti-religious propaganda and oppression of the clergy, beginning with collectivization. Narratives are rural priests, and it refl ects their own perception of the key events of the age. The author in the article examines the attitude of the parishioners to the Church, their perception of current events, participation in parish life. He concludes on a high degree of involvement of Cossacks in the Church life, the importance of the Church in their daily lives. The facts given in the article, suggest the sustainability of the parish farm, the community was able to survive in the turmoil of the Civil war. Forced destruction of parish life in the years of collectivization destroyed the community and has led to the degradation and disappearance of rural settlement. The last author of the chronicle was repressed, he and those arrested with him the clergy and parishioners were accused of preparing an armed uprising. The chronicle shows that this

  1. Degradação de deoxinivalenol (DON) e a atividade da enzima peroxidase durante fermentação submersa

    OpenAIRE

    Garda-Buffon, Jaqueline; Kupski, Larine; Badiale-Furlong, Eliana

    2011-01-01

    This work aims to evaluate deoxynivalenol degradation by Aspergillus oryzae and Rhizopus oryzae in a submerged fermentation system and to correlate it to the activity of oxydo-reductase enzymes. The submerged medium consisted of sterile distilled water contaminated with 50 μg of DON and 4 × 10(6) spore.mL-1 inoculum of Aspergillus oryzae and Rhizopus oryzae species, respectively in each experiment. Sampling was performed every 24 hours for monitoring the peroxidase specific activity, and ever...

  2. Formation of post-fire water-repellent layers in Monterrey pine (Pinus radiata D. Don) plantations in south-central Chile

    Science.gov (United States)

    P. Garcia-Chevesich; R. Pizarro; C. L. Stropki; P. Ramirez de Arellano; P. F. Ffolliott; L. F. DeBano; Dan Neary; D. C. Slack

    2010-01-01

    A wildfire burned about 15,000 ha of Monterrey Pine (Pinus radiata D. Don) plantations near Yungay, Chile, in January of 2007. Post-fire water repellency (hydrophobicity) was measured using the water-drop-penetration-time (WDPT) method at depths of 0, 5, and 10 mm from the soil surface. These measurements were collected on burned sites of both young (4-years old) and...

  3. Feminism Spirit Toward Patriarchal Society Manifestated by Kate Reddy in I Don't Know How She Does IT the Movie

    OpenAIRE

    RAMDHANI, NADIYA FARISYA

    2015-01-01

    Keywords: Feminism, Patriarchal Society, Working WomenWomen subordination has running for a long time ago. Women are trapped by patriarchal society's rule on how they should be. Women never have the opportunities to get a better quality of life, such as education or career. Nowadays, women have more chance to free themselves from that social construction. The movie entitled I Don't Know How She Does It reveals working woman's life surrounded by patriarchal society and her effort to prove that...

  4. Views on agrarian question in the russian empire early twentieth century public don (on the example of V.I. Denisov

    Directory of Open Access Journals (Sweden)

    Z. V. Svyaschenko

    2014-09-01

    Full Text Available The article highlights the essence of agrarian nobility Don initiatives as an example of marshal of the nobility of the Don area V.I. Denisova, draws attention to the radical changes large landowners understand the nature of the agrarian question. Detailed analysis of vision causes aggravation and solving agricultural problems under conditions of revolution «Union supporters peaceful resolution of the agrarian question», which was organized by Don autumn 1905 Union believed that the government should immediately allow farmers free access to the community with fixing them processed before this allotment in private ownership and the right of selling. The analysis looks marshal of the nobility area of the Don V. Denisov, according to which land reform must be focused on the transition from communal farmers to homestead entities on the basis of peasant private ownership of land, increasing the size of peasant land ownership through the purchase of additional land they or their resettlement intensification individual farm. A general conclusion is that the views of V.I. Denisov and other landowners reflect the general mood and position of large landowners on agricultural issues. Their analysis shows a major fact of evolution beliefs representatives of large estates. As the patriots of their country, they offered very real steps to address not only the agricultural problems and to improve general well-being of the population, increasing the efficiency of the economy and legal equality of different layers Russian imperial society and so on. A large estates in various regions of the country were unanimous that stop the deployment of revolutionary elements in the country is possible only on one condition - the resolution of the agrarian question.

  5. A NEW MODULA TYPO-DIMENSIONAL, CONSTRUCTIVE AND FUNCTIONAL CONCEPT OF VIVA DON EXPERT® FLOATABLE FISH CAGES FOR INTENSIVE AQUACULTURE IN INLAND WATERS

    OpenAIRE

    D. ONEA; V. CRISTEA

    2009-01-01

    This scientific work presents succinct information about the trials which takes place between 2005-2009 in Constanta (fish farm Canalul Rompetrol). This trials includes the fish farming in cages and leads to finishing off and elaboration of a new modular typo-dimensional, constructive and functional concept of viva don Expert® floatable fish cages for intensive aquaculture in inland waters from Romania like an efficient solution for the qualitative and quantitative increase of local fish prod...

  6. The Trading Company of the Don Cossacks and MLiTAO in 1917: Breaking Traditional Foundations or Adapting to New Conditions. Based on the Materials of the GARO

    Directory of Open Access Journals (Sweden)

    Yuri A. Bulygin

    2017-12-01

    Full Text Available The article analyzes the state of the Cossack business communities of the Trade Society and MLiTAO during the revolutionary period of 1917. The expediency of scientific research for modern science and practice consists in finding the experience of work of business organizations in the acute crisis conditions of revolutionary time. The documents of the Trading Society of Don Cossacks in 1917 are confused and devoid of the former system. There are no reports of meetings of trustees, reviews of the socio-economic situation on the state of the branches of production. The main activity was aimed at the fulfillment of supplies related to military needs, the organization of self-protection of the military territories, attempts to clarify its own future under the new conditions. The work of the MLiTAO was more practical, the documents were devoted to economic issues and did not affect participation in the revolutionary events of 1917. The materials confirm the existence of an unstable situation, but do not contain information indicating a deep crisis, stopping or malfunctioning of organizations. This is due to the fact that large-scale military operations on the Don began after 1917. Separate cases of transition to a natural exchange or violation of supply contracts can not affirmatively answer the question of feudalization or the nature of the changes in capitalist relations in the region. Don entrepreneurs perceived political transformations as an update of the political system, democratic changes.

  7. On the Paleopathological Features of the Sarmatian Population of the Lower Volga and the Lower Don Regions in the 4th - 1st Centuries B.C.

    Directory of Open Access Journals (Sweden)

    Pererva Evgeniy Vladimirovich

    2015-12-01

    Full Text Available The paper is dedicated to the study of paleopathological features of the early Sarmatians. The bone remains which are the material to this research originate from tombs beneath burials mounds from the area of the Lower Volga and the Lower Don regions. The author applied the technique of analysis of bone remains that was introduce into scientific use by A.P. Buzhilova. As a result of the conducted research, the author found out that the early Sarmatians are most likely to have come from the Lower Volga and the Don regions being migrating population which was not uniform in its composition. Some of the Sarmatians, men, in the first place, were overweight and suffered from obesity. The early Sarmatian population in the Lower Volga region and the Don region experienced the periods of prolonged starvation that resulted in chronic diseases which were exacerbated during winters or in dry years. At the same time, the Sarmatians rarely suffered from specific infectious diseases due to the low density of population. War was an integral part of the Sarmatian that was often reflected on skull bones and post-cranial skeleton as war wounds and traumas due to ritual ceremonies.

  8. Don Juan: eine Tragödie. Intertestualità faustiana e riscrittura tragica nel racconto di E. T. A. Hoffmann

    Directory of Open Access Journals (Sweden)

    Francesco Marola

    2017-11-01

    Full Text Available Il mito letterario di don Giovanni, sorto nella commedia, attorno al 1800 viene riformulato in direzione del tragico. La trasformazione inizia con la versione operistica di Mozart-Da Ponte e trova compimento nel racconto di Hoffmann, che proietta il nuovo tono tragico del finale mozartiano su tutto il mito. L’articolo intende porre in rilievo la presenza nel Don Juan di numerosi richiami intertestuali al Faust di Goethe, finora non pienamente rilevati dalla critica, attraverso i quali è possibile leggere tale riscrittura tragica come una dichiarata sintesi dei due miti, in cui don Giovanni assume il ruolo di Faust-Mefistofele e donna Anna quello di Gretchen. La riscrittura del mito culmina nel finale rispecchiamento del narratore in Anna-Gretchen. Ma il valore del tragico è relativizzato in Hoffmann dall’ironica autocoscienza dell’artista romantico: confinato nel mondo fantastico dell’arte, risulta privo di senso nella prosaica realtà della vita borghese.

  9. Adult and child use of love, like, don't like and hate during family mealtimes. Subjective category assessments as food preference talk.

    Science.gov (United States)

    Wiggins, Sally

    2014-09-01

    Food preference is now a ubiquitous concept in eating research, and closely associated with actual consumption, particularly in relation to children's food preferences. Research in this area is beginning to reveal the effects of parent-child interaction on eating practices though relatively little attention has been paid to the discursive and lexical processes involved. Food preferences are typically associated with the terms 'likes' and 'dislikes' in food preference research. By contrast, adults and children typically use the terms 'love', 'like', 'don't like' and 'hate' to construct and manage food preferences in everyday meal conversations. A corpus of 270 video- and audio-recorded English and Scottish family mealtimes, involving children aged 1-17 years, was searched and analysed for any and all occurrences of subjective category assessments (SCAs; e.g., 'I like X'), featuring the terms 'love', 'like', 'don't like' and 'hate'. Discursive psychology was used to analyse the transcripts and recordings, and illustrated the disparity between adult and child use of SCAs and food preference talk. Within the data set, parents typically made claims about what their children like, and in doing so claimed epistemic primacy over their children's food preferences. Children, by contrast, typically made claims about their own 'don't likes' and likes, and these were frequently countered by their parents or treated as inappropriate claims. Implications for how parents and researchers might reorient to the food preferences lexicon are discussed. Copyright © 2014 Elsevier Ltd. All rights reserved.

  10. Algunas hazañas de las muchas de don García Hurtado de Mendoza, comedia genealógica de nueve ingenios

    Directory of Open Access Journals (Sweden)

    Carlos Mata Induráin

    2013-12-01

    Full Text Available Algunas hazañas de las muchas de don García Hurtado de Mendoza, marqués de Cañete, pieza escrita en colaboración por nueve ingenios encabezados por Luis de Belmonte Bermúdez, se representó y publicó en Madrid en 1622. Se trata de una comedia genealógica de encargo, que formó parte de la campaña de propaganda emprendida por la familia de los Hurtado de Mendoza para prestigiar la figura de don García Hurtado de Mendoza, cuarto marqués de Cañete, quien como gobernador de Chile (1557-1561 había logrado notables avances en la pacificación del rebelde territorio de Arauco, pero cuyos méritos no quedaron reconocidos por Alonso de Ercilla en La Araucana. Se estudia, sobre todo, la imagen que la pieza ofrece del noble personaje en el contexto de su actuación en la guerra de Arauco, la cual generó en el Siglo de Oro un abundante corpus de obras literarias. Algunas hazañas de las muchas de don García Hurtado de Mendoza, marqués de Cañete, collaborated play by nine playwrights headed by Luis Belmonte Bermúdez, was represented and published in Madrid in 1622. It´s a genealogical comedy, which was part of the propaganda campaign launched and paid by Hurtado de Mendoza’s family, in order to give prestige to the figure of don García Hurtado de Mendoza, 4th Marquis of Cañete, who as Governor of Chile (1557-1561 had achieved remarkable progress in pacifying the rebellious territory of Arauco, but whose merits were not recognized by Alonso de Ercilla in La Araucana. The article studies the image of don García in the context of the Arauco War, which generated a rich corpus of literary works in the Spanish Golden Age. Key words: Spanish Drama of the Golden Age, genealogical comedy, theatre and patronage, García Hurtado de Mendoza, Arauco war, Luis de Belmonte Bermúdez, collaborated comedy.

  11. Dendroecological studies of rhododendron campanulatum d. don along the elevational gradient of manaslu conservation area, nepal himalaya

    International Nuclear Information System (INIS)

    Prabinarana, A.; Koirala, M.; Boonchird, C.

    2017-01-01

    The increase in temperature due to global warming is affecting forest ecosystems worldwide. At the treeline ecotone growth is usually restricted by low temperatures. Recently, the impacts of climate change have been visible with the upward shift of the Himalaya fir (Abies spectabilis) in Nepal. Rhododendron campanulatum D. Don grows at the treeline ecotone and subalpine forest. Hardly any studies have been carried on this species in Nepal. The local people have reported that this species has been seen colonizing upper altitude in recent years, however, these needs to be verified with dendroecological studies. The study aims to assess the response of R. campanulatum to climatic variability and to evaluate the relationship of its basal diameter (Groundline) and age using dendroecological methods. Results reveal that the basal diameter was found to be significantly correlated with age (r2= 0.824, p<0.00001). Using the basal diameter age equations, attempts were made to study the age distribution along the altitudinal gradient. The species limit was observed at 4090 m asl. The age structure differed along the altitudinal gradient with multi age cohorts below the treeline and younger cohorts above the treeline. Results show that this species is migrating up at a rate of 24.7m per decade. (author)

  12. Interpreting "I don't know" use by persons living with dementia in Mini-Mental State Examinations.

    Science.gov (United States)

    Hesson, Ashley M; Pichler, Heike

    2016-09-01

    We investigate dementia patients' use of "I don't know" (IDK) in Mini-Mental State Exams (MMSEs) using objective linguistic indicators to differentiate IDK signalling lack of knowledge (LOK) from IDK used to hedge responses, affect exam progression etc. We hypothesize that increased proportional use of LOK-IDK correlates with worsening dementia severity. 189 IDK tokens were extracted from 72 MMSE interactions and coded for linguistic/social characteristics. A data-driven, discourse position/relation-based functional taxonomy for IDK in MMSE was developed and the resulting functional distribution was subjected to multiple logistic regression. Use of LOK-IDK (vs. non-LOK-IDK) is significantly correlated (p=0.01) with clinicians' subjective ratings of patients' dementia as 'severe' vs. 'mild'/'moderate', indicating that objective sociolinguistic criteria approximate physician judgments. 92% of 'severe' patients' IDKs signalled LOK, compared to only 68% of 'mild' patients', suggesting that uncritical interpretation of IDK as signalling LOK would result in 8-32% of IDK responses being mis-scored. LOK and non-LOK uses distinguished on the basis of reliable, objective usage patterns are differentially distributed among dementia severity groups. LOK-IDK serves as a supplemental indicator of dementia severity. Correct interpretation may improve diagnostic accuracy and allow clinicians to respond supportively during cognitive assessment. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  13. 'Don't save her'- Sigmund Freud meets Project Pat: the rescue motif in hip-hop.

    Science.gov (United States)

    Fulmer, Richard H

    2008-08-01

    Freud originally explicated the dynamics of rescue wishes by describing men who fell in love with prostitutes. He saw this attempt at attachment as driven by the man's wish to repay his parents for giving him life. Many subsequent writers shift this emphasis, seeing rescue wishes as motivated by aggressive oedipal competition with the father. This article highlights the attachment aspects of Freud's original conception and traces how writers in the last three decades use the family romance rather than Oedipus as a model to view rescue wishes as having a more tender aspect. Rescue wishes are especially characteristic of the developmental stage of young adulthood. They at once attempt to repay the parental debt the young adult feels and serve as practice for the vicissitudes of the couple bond and the benign sacrifices of parenthood. Popular culture contains many vivid examples of Freud 's original description of the rescue-motif. A detailed examination of the rap song, Don't save her, demonstrates all the elements of Freud's original conception and the interpersonal risks of the rescue relationship. Three additional rap songs by other artists are briefly analyzed to show the extensive occurrence of the wish to rescue and its psychic and interpersonal dangers.

  14. Study on the structures and anti-hepatic fibrosis activity of stilbenoids from Arundina graminifolia (D. Don) Hochr.

    Science.gov (United States)

    Liu, Qingqing; Wang, Huiting; Lin, Fankai; Dai, Rongji; Yu, Deng lin; Lv, Fang

    2017-12-01

    A phytochemical study was performed on Arundina graminifolia (D.Don) Hochr. by silica gel column and semi-preparative HPLC, and ten stilbenoids were obtained. Their structures were elucidated by NMR and MS spectra and identified as 7-hydroxy-2,4-dimethoxy-9,10-dihydrophenanthrene (1), 4,7-dihydroxy-2-methoxy-9,10-dihydrophenanthrene (2), 2,7-dihydroxy-4-methoxy-9,10-dihydrophenanthrene (3), 3,3’-dihydroxy-5-methoxy-bibenzyl (4), 7-hydroxy-2,8-dimethoxy-phenanthrene-1,4-dione (5), 7-hydroxy-2,10-dimethoxy-phenanthre-ne-1,4-dione (6), 7-dihydroxy-2-methoxy-9,10-dihydrophenanthrene-1,4-dione (7), 7-hydroxy-2-methoxy-phenanthrene-1,4-dione (8), 7-hydroxy-1-(p-hydroxybenzyl)-2,4-dimethoxy-9,10-dihydroxy-phenanthrene (9), 2,7-dihydroxy-1-(p-hydroxybenzyl)-4-methoxy-9,10-dihydroxy-phenanthrene (10). Compounds 5 and 6 were isolated from this plant for the first time. The isolated compounds were examined for their anti-hepatic fibrosis activity against HSC-T6 cells in vitro. The results showed that compounds 4 and 5 exhibited moderate growth inhibitory effects with IC50 61.9 μg/mL and 52.7 μg/mL, respectively.

  15. Sherlock Holmes' or Don Quixote`s certainty? Interpretations of cropmarks on satellite imageries in archaeological investigation

    Science.gov (United States)

    Wilgocka, Aleksandra; RÄ czkowski, Włodzimierz; Kostyrko, Mikołaj; Ruciński, Dominik

    2016-08-01

    Years of experience in air-photo interpretations provide us to conclusion that we know what we are looking at, we know why we can see cropmarks, we even can estimate, when are the best opportunities to observe them. But even today cropmarks may be a subject of misinterpretation or wishful thinking. The same problems appear when working with aerial photographs, satellite imageries, ALS, geophysics, etc. In the paper we present several case studies based on data acquired for and within ArchEO - archaeological applications of Earth Observation techniques project to discuss complexity and consequences of archaeological interpretations. While testing usefulness of satellite imagery in Poland on various types of sites, cropmarks were the most frequent indicators of past landscapes as well as archaeological and natural features. Hence, new archaeological sites have been discovered mainly thanks to cropmarks. This situation has given us an opportunity to test not only satellite imageries as a source of data but also confront them with results of other non-invasive methods of data acquisition. When working with variety of data we have met several issues which raised problems of interpretation. Consequently, questions related to the cognitive value of remote sensing data appear and should be discussed. What do the data represent? To what extent the imageries, cropmarks or other visualizations represent the past? How should we deal with ambiguity of data? What can we learn from pitfalls in the interpretation of cropmarks, soilmarks etc. to share more Sherlock's methodology rather than run around Don Quixote's delusions?

  16. Laws of Contamination and Blend. Don DeLillo and Jean-luc Godard: an Illuminating Challenge

    Directory of Open Access Journals (Sweden)

    Mariangela Bio

    2012-07-01

    Full Text Available Aim The present paper aims at highlithing the new dynamics of comparison and exchange between literature and arts. It assumes the idea of a literature centred on the relations between text and context, bent on exhalting its "social" disposition. Then it deals with the subject of the work's originality in terms of identitary pact constantly renegotiated with works belonging to other semiologic themes. In this perspective, this article briefly investigates the complex relation between Don De Lillo's and Jean-Luc Godard's works. Methodology The analytic approach moves between comparative literature and cultural criticism, in a very well-known field in the area of traditional literary studies and a very important sector in the structuration of contemporary imaginary: the relation between literature and cinema. The methodology adopted employs the comparative dynamics typical of text semiotcs, to underline exchange categories, among different languages and codes, which prove to be flowing, open and constantly changing. Results The article highlights and explores new possibilities in the relation between cinema and literature, investigating them on the basis of the present observations on the notion of text; it also explains the urgency of a semantic reassessment of the concept of "work's originality" in the contemporary semiosphere.

  17. Studies on cytological, physiological and genetic characteristics in somatic mutant strains of Sugi (Cryptomeria japonica D. Don)

    International Nuclear Information System (INIS)

    Maeta, T.; Somegou, M.; Nakahira, K.; Miyazaki, Y.; Kondo, T.

    1982-01-01

    From microscopic observation of the pollen of induced mutant strains in Sugi (Cryptomeria japonica D. Don), it was found that there were large differences in pollen fertility among the mutant strains, and that it deviated year to year from the mother plants. The large differences in frequency of sterile pollen among mutant strains depended on the genetic characteristics of each mutant strain. Higher frequencies of sterile pollen were observed at the terminal part of branchlets in some mutant strains, and this was considered to be induced by the lateness of flower-bud formation at low temperature conditions in late summer. Delayed formation and gibberellic acid treatment applied for flower induction resulted in low fertility and abnormality of pollen in mutant strains. Chromosome aberration in mutant strains was caused either by gamma irradiation or by some mutational events that responded to environmental conditions. In the former case, aberration might have been maintained for a long period through vegetative propagation. Some of the irregularities were due to mitotic cell division, because cells with micronuclei at the pacytene stage in pollen mother cells and with fragments at MI were observed. Somatic mutability of Kuma-sugi mutants after re-irradiation was investigated. From waxless mutants morphological somatic mutations, which have fat or stout stems and thick and short needles, were frequently produced, whereas from morphological mutants the lowest somatic mutation frequency was induced. In some mutant strains higher rooting ability than the mother plants was found, and the possibility of character improvement was pointed out. (author)

  18. Proliferation and ajmalicine biosynthesis of Catharanthus roseus (L). G. Don adventitious roots in self-built temporary immersion system

    Science.gov (United States)

    Phuc, Vo Thanh; Trung, Nguyen Minh; Thien, Huynh Tri; Tien, Le Thi Thuy

    2017-09-01

    Periwinkle (Catharanthus roseus (L.) G. Don) is a medicinal plant containing about 130 types of alkaloids that have important pharmacological effects. Ajmalicine in periwinkle root is an antihypertensive drug used in treatment of high blood pressure. Adventitious roots obtained from periwinkle leaves of in vitro shoots grew well in quarter-strength MS medium supplemented with 0.3 mg/l IBA and 20 g/l sucrose. Dark condition was more suitable for root growth than light. However, callus formation also took place in addition to the growth of adventitious roots. Temporary immersion system was applied in the culture of adventitious roots in order to reduce the callus growth rate formed in shake flask cultures. The highest growth index of roots was achieved using the system with 5-min immersion every 45 min (1.676 ± 0.041). The roots cultured in this system grew well without callus formation. Ajmalicine content was highest in the roots cultured with 5-min immersion every 180 min (950 μg/g dry weight).

  19. Toxicological features of maleilated polyflavonoids from Pinus radiata (D. Don.) as potential functional additives for biomaterials design.

    Science.gov (United States)

    García, Danny E; Medina, Paulina A; Zúñiga, Valentina I

    2017-11-01

    Polyflavonoids from Pinus radiata (D. Don.) are an abundant natural oligomers highly desirable as renewable chemicals. However, structural modification of polyflavonoids is a viable strategy in order to use such polyphenols as macrobuilding-blocks for biomaterial design. Polyflavonoids were esterified with three five-member cyclic anhydrides (maleic, itaconic, and citraconic) at 20 °C during 24 h in order to diversify physicochemical-, and biological-properties for agricultural, and food-packaging applications. In addition, the influence of the chemical modification, as well as the chemical structure of the grafting on toxicological features was evaluated. Structural features of derivatives were analyzed by spectroscopy (FT-IR and 1 H-NMR), and the degree of substitution was calculated. Toxicological profile was assessed by using three target species in a wide range of concentration (0.01-100 mgL - 1 ). Effect of polyflavonoids on the growth rate (Selenastrum capricornutum), mortality (Daphnia magna), and germination and radicle length (Lactuca sativa) was determined. Chemical modification affects the toxicological profile on the derivatives in a high extent. Results described remarkable differences in function of the target specie. The bioassays indicate differences of the polyflavonoids toxicological profile associated to the chemical structure of the grafting. Results allowed conclude that polyflavonoids from pine bark show slight toxic properties. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. ’Freud is finished, Einstein’s next’: Don DeLillo’s Cosmopolis, Chaos Theory, and Quantum Entanglement

    Directory of Open Access Journals (Sweden)

    Crystal Alberts

    2016-05-01

    Full Text Available This essay argues that, in 'Cosmopolis', DeLillo returns to mathematical topics and formal structures, like those presented in Ratner's Star, and expands them to reflect more recent developments in science and technology to contemplate time—the subject that permeates many of his twenty first century novels—and to highlight, variously, the unpredictable, uncertain, interconnected, and illusory nature of the contemporary world. Written in between the dot-com bubble burst and the aftermath of September 11, 2001, this essay asserts that 'Cosmopolis' is liminal: it offers a glimpse of the ruins of the future, and as one of its rejected titles suggests, it approaches an omega point. Drawing heavily on archival research in the 'Don DeLillo Papers' at University of Texas, Austin's Harry Ransom Center, this essay contends that 'Cosmopolis' is a thought experiment, of sorts, in which DeLillo incorporates his substantial and ongoing research on strange attractors, quantum entanglement, and the physics of time to consider the "[t]wo forces in this world, past and future." In doing so, this essay suggests that DeLillo calls for a reassessment of the time in which this text is set and proposes an alternate way of perceiving the post-9/11 world.

  1. Biochemical characterization of Helichrysum italicum (Roth) G.Don subsp. italicum (Asteraceae) from Montenegro: phytochemical screening, chemotaxonomy, and antioxidant properties.

    Science.gov (United States)

    Kladar, Nebojša V; Anačkov, Goran T; Rat, Milica M; Srđenović, Branislava U; Grujić, Nevena N; Šefer, Emilia I; Božin, Biljana N

    2015-03-01

    The chemical composition and antioxidant properties of the essential oil and EtOH extract of immortelle (Helichrysum italicum (Roth) G.Don subsp. italicum, Asteraceae) collected in Montenegro were evaluated. The essential oil was characterized by GC/MS analysis, and the content of total phenolics and flavonoids in the EtOH extract was determined using the FolinCiocalteu reagent. The free-radical-scavenging capacity (RSC) of both the essential oil and the EtOH extract was assessed with the 2,2-diphenyl-1-pycrylhydrazyl (DPPH) method. Moreover, the inhibition of hydroxyl radical ((.) OH) generation by the EtOH extract of immortelle was evaluated for the first time here. Neryl acetate (28.2%) and γ-curcumene (18.8%) were the main compounds in the essential oil, followed by neryl propionate (9.1%) and ar-curcumene (8.3%). The chemical composition of the oils of the examined and additional 16 selected Helichrysum italicum taxa described in literature were compared using principal component (PCA) and cluster (CA) analyses. The results of the statistical analyses implied the occurrence of at least four different main and three subchemotypes of essential oils. Considering the antioxidant properties, the EtOH extract of immortelle exhibited similar potential as propyl gallate and quercetin, while the essential oil exhibited relatively weak DPPH(.) -scavenging capacity. Copyright © 2015 Verlag Helvetica Chimica Acta AG, Zürich.

  2. In the future, toward death: Finance capitalism and security in Don DeLillo’s ‘Cosmopolis’

    Directory of Open Access Journals (Sweden)

    Johannes Voelz

    2018-05-01

    Full Text Available This article develops a reading of Don DeLillo’s novel Cosmopolis that differentiates between two thematic and poetological axes running through the text. On the one hand, Cosmopolis explores the future-fixation of the risk regime of finance capitalism; on the other, it stages scenes of insecurity that physically threaten the protagonist and his world. Insecurity, the article argues, is a condition that throughout the text increasingly gains in appeal because it promises to offer an alternative to a world of managed risk. The concern with security emphasizes finitude and mortality, thus enabling a turn to existential matters that the virtual abstractions of finance have seemingly made inaccessible. While proposing an opposition between a logic of risk based on virtuality and a logic of (insecurity based on authenticity, DeLillo’s novel also suggests that it is impossible to break out of the logic of risk management pervading late modernity. The appeal of (insecurity articulated in Cosmopolis rather lies in the promise to existentially revitalize life within the confines of financialized capitalism.

  3. Functional components in Scutellaria barbata D. Don with anti-inflammatory activity on RAW 264.7 cells

    Directory of Open Access Journals (Sweden)

    Hsin-Lan Liu

    2018-01-01

    Full Text Available The objectives of this study were to determine the variety and amount of various functional components in Scutellaria barbata D. Don as well as study their anti-inflammatory activity on RAW 264.7 cells. Both ethanol and ethyl acetate extracts were shown to contain the functional components including phenolics, flavonoids, chlorophylls, and carotenoids, with the former mainly composed of phenolics and flavonoids, and the latter of carotenoids and chlorophylls. Both extracts could significantly inhibit (p < 0.05 the production of lipopolysaccharide-induced nitric oxide, prostaglandin E2, interlukin-6, and interlukin-1β, as well as the expressions of phosphor extracellular signal-regulated kinase and phosphor-c-Jun N-terminal kinase (p-JNK, but failed to retard tumor necrosis factor-α expression. Both ethanol and ethyl acetate extracts had a dose-dependent anti-inflammatory activity on RAW 264.7 cells. Furthermore, the anti-inflammatory efficiency can be varied for both ethanol and ethyl acetate extracts, which can be attributed to the presence of different varieties and amounts of functional components, as mentioned above. This finding suggested that S. Barbata extract may be used as an anti-inflammatory agent for possible future biomedical application.

  4. Sombreamento de plantas de Catharanthus roseus (L. G. Don 'Pacifica White' por malhas coloridas: desenvolvimento vegetativo Shading of 'Pacifica White' Catharanthus roseus (L. G. Don plants with colored nets: vegetative development

    Directory of Open Access Journals (Sweden)

    Anderson Adriano Martins Melo

    2009-04-01

    Full Text Available As malhas coloridas têm sido utilizadas para manipular o desenvolvimento vegetativo, melhorando a utilização da radiação solar por plantas ornamentais. Objetivou-se, neste trabalho estudar o efeito da redução de 50% da radiação fotossinteticamente ativa sobre o crescimento vegetativo de plantas de Catharanthus roseus (L. G. Don, por meio de malhas azul e vermelha e malha preta, em comparação com plantas crescidas na ausência de sombreamento (pleno sol. As plantas foram obtidas a partir de sementes e tratadas por 180 dias. Foram avaliados o ganho de biomassa e a distribuição de matéria seca nas plantas, o conteúdo de pigmentos foliares (clorofilas e carotenóides e de nitrogênio foliar. A malha vermelha provocou um aumento de matéria seca total e de área foliar das plantas em comparação com as malhas azul, preta e ao tratamento a pleno sol, porém, exceto em relação a esse tratamento, a malha vermelha causou menor conteúdo de nitrogênio e pigmentos foliares. A maior relação raiz/parte aérea e relação clorofila a/b, menores razões de área foliar e de massa foliar das plantas crescidas a pleno sol em relação às plantas sombreadas indicam um efeito mais proeminente da irradiância mais alta do que da alteração do espectro de luz. O sombreamento altera significativamente a distribuição de matéria seca e o uso de malhas de diferentes cores modifica o conteúdo de pigmentos fotossintéticos dessa espécie.Colored shade nets have been used to manipulate the vegetative development, improving the utilization of solar radiation by ornamental plants. This work aimed to study the effect of 50% reduction of PAR on vegetative growth of plants of Catharanthus roseus (L. G. Don, using blue and red nets, and black net, in comparison to plants growing under full sunlight (lack of shading. The plants were obtained from seeds and treated for 180 days. Biomass increment and distribution, pigment content (chlorophylls and

  5. Searching for magnetic fields in 11 Wolf-Rayet stars: Analysis of circular polarization measurements from ESPaDOnS

    Energy Technology Data Exchange (ETDEWEB)

    De la Chevrotière, A.; St-Louis, N.; Moffat, A. F. J. [Centre de Recherche en Astrophysique du Québec (CRAQ), Département de physique, Université de Montréal, C.P. 6128, Succ. Centre-ville, Montréal, Québec H3C 3J7 (Canada); Collaboration: MiMeS Collaboration

    2014-02-01

    With recent detections of magnetic fields in some of their progenitor O stars, combined with known strong fields in their possible descendant neutron stars, it is natural to search for magnetic fields in Wolf-Rayet (WR) stars, despite the problems associated with the presence of winds enhanced by an order of magnitude over those of O stars. We continue our search among a sample of 11 bright WR stars following our introductory study in a previous paper of WR6 = EZ CMa using the spectropolarimeter ESPaDOnS at Canada-France-Hawaii Telescope, most of them in all four Stokes parameters. This sample includes six WN stars and five WC stars encompassing a range of spectral subclasses. Six are medium/long-period binaries and three show corotating interaction regions. We report no definite detections of a magnetic field in the winds in which the lines form (which is about the same distance from the center of the star as it is from the surface of the progenitor O star) for any of the eleven stars. Possible reasons and their implications are discussed. Nonetheless, the data show evidence supporting marginal detections for WR134, WR137, and WR138. According to the Bayesian analysis, the most probable field intensities are B {sub wind} ∼ 200, 130, and 80 G, respectively, with a 95.4% probability that the magnetic fields present in the observable parts of their stellar wind, if stronger, does not exceed B{sub wind}{sup max}∼1900 G, ∼1500 G, and ∼1500 G, respectively. In the case of non-detections, we report an average field strength upper limit of B{sub wind}{sup max}∼500 G.

  6. Evaluation of phytochemical content, antimicrobial, cytotoxic and antitumor activities of extract from Rumex hastatus D. Don roots.

    Science.gov (United States)

    Sahreen, Sumaira; Khan, Muhammad Rashid; Khan, Rahmat Ali; Hadda, Taibi Ben

    2015-07-03

    Being a part of Chinese as well as ayurdic herbal system, roots of Rumex hastatus D. Don (RH) is highly medicinal, used to regulated blood pressure. It is also reported that the plant is diuretic, laxative, tonic, used against microbial skin diseases, bilious complaints and jaundice. The present study is conducted to evaluate phytochemical, antimicrobial, antitumor and cytotoxic activities of extract obtained from R. hastatus roots. RH roots were powdered and extracted with methanol to get crude extract. Crude extract was further fractioned on the basis of increasing polarity, with n-hexane (HRR), chloroform (CRR), ethyl acetate (ERR), n-butanol (BRR) and residual aqueous fraction (ARR). Methanol extract and its derived fractions were subjected to phytochemical screening and assayed for antibacterial activities via agar well diffusion method. Antifungal activities were checked through agar tube dilution method whereas potato disc assay was employed for the determination of antitumor activity. On the other hand cytotoxic activities were conducted using brine shrimps procedures. The results obtained from phytochemical analysis indicate the presence of alkaloids, anthraquinones, flavonoids and saponins in all the fractions. Most of the plant fractions showed substantial antimicrobial activities, which is in accordance with the spacious use of tested plant samples in primary healthcare center. Fractions of R. hastatus roots for cytotoxicity were tested as an effective cytotoxic was found as BRR > MRR > CRR > ARR > ERR > HRR. Ranking order of fractions of R. hastatus roots for effective antitumor screening was found as MRR > BRR > ARR > CRR > ERR > HRR. These results showed that R. hastatus appeared as an important source for the discovery of new antimicrobial drugs and antitumor agents; verify its traditional uses and its exploitation as therapeutic agent.

  7. Ethno-botanical study of the African star apple (Chrysophyllum albidum G. Don in the Southern Benin (West Africa

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    Houessou Laurent G

    2012-10-01

    Full Text Available Abstract Background In addition to plant species biology and ecology, understanding the folk knowledge systems related to the use of plant species and how this knowledge system influences the conservation of plant species is an important issue in the implementation of sustainable strategies of biodiversity conservation programs. This study aimed at providing information on the use and local knowledge variation on Chrysophyllum albidum G. Don a multipurpose tree species widely used in southern Benin. Methods Data was collected through 210 structured interviews. Informants were randomly selected from ten villages. The fidelity level and use value of different plant parts of C. albidum were estimated. The variation in ethnobotanical knowledge was assessed by comparing the use value between ethnic, gender and age groups. In order to assess the use pattern of the different plant parts in folk medicine, a correspondence analysis was carried out on the frequency citation of plant parts. Results Four categories of use (food, medicine, firewood and timber were recorded for C. albidum. With respect to the different plant parts, the fleshy pulp of the African star apple fruit showed high consensus degree as food among the informants. Fifteen diseases were reported to be treated by the different parts of C. albidum in the region. Correspondence analysis revealed the specificity of each part in disease treatment. There was no significant difference among ethnic groups regarding the ethno-botanical use value of C. albidum. However, significant difference existed between genders and among age groups regarding the knowledge of the medical properties of this species. Conclusions C. albidum is well integrated in the traditional agroforestry system of the southern Benin. Despite its multipurpose character, this species remains underutilized in the region. Considering the current threat of habitat degradation, action is needed in order to ensure the long term

  8. The effect of water availability on plastic responses and biomass allocation in early growth traits of Pinus radiata D. Don

    Energy Technology Data Exchange (ETDEWEB)

    Espinoza, S. E.; Magni, C. R.; Martinez, V. A.; Ivkovic, M.

    2013-05-01

    Aim of study: The aim of the study was to assess the effect of water availability on plastic responses and biomass allocation in early growth traits of Pinus radiata D. Don. Area of study: Seedlings of 69 families of P. radiata belonging to five different sites in Central Chile, ranging from coastal range to fothills of the Andes, were grown in controlled conditions to evaluate differences in response to watering. Material and methods: The seedlings were subjected to two watering regimes: well-watered treatment, in which seedlings were watered daily, and water stress treatment in which seedlings were subjected to three cyclic water deficits by watering to container capacity on 12 days cycles each. After twenty-eight weeks root collar diameter, height, shoot dry weight (stem + needles), root dry weight, total dry weight, height/diameter ratio and root/shoot ratio were recorded. Patterns and amounts of phenotypic changes, including changes in biomass allocation, were analyzed. Main results: Families from coastal sites presented high divergence for phenotypic changes, allocating more biomass to shoots, and those families from interior sites presented low phenotypic plasticity, allocating more biomass to roots at the expense of shoots. These changes are interpreted as a plastic response and leads to the conclusion that the local land race of P. radiata in Chile originating from contrasting environments possess distinct morphological responses to water deficit which in turn leads to phenotypic plasticity. Research highlights: Families belonging to sandy soil sites must be considered for tree breeding in dry areas, selecting those with high root: shoot ratio. (Author) 46 refs.

  9. The geochemistry of Don Juan Pond: Evidence for a deep groundwater flow system in Wright Valley, Antarctica

    Science.gov (United States)

    Toner, J. D.; Catling, D. C.; Sletten, R. S.

    2017-09-01

    Don Juan Pond (DJP), Antarctica, is one of the most unusual surface waters on Earth because of its CaCl2-rich composition. To investigate the evolution of pond waters during closed-basin evaporation and to understand the source of brines responsible for the chemistry of DJP, we apply a newly developed low-temperature aqueous model in the Na-K-Ca-Mg-Cl system to DJP. By modeling the closed-basin evaporation of DJP and comparing ionic ratios between DJP surface water, deep groundwater, shallow groundwater, and other surface chemistries in Wright Valley, we find that DJP is best explained by upwelling deep groundwater, as opposed to recent hypotheses proposing shallow groundwater sources. The early closed-basin evolution of brines in our model accurately predicts observed chemistries in DJP; however, late-stage closed-basin evaporation produces Mg-K-rich brines and salts that do not match the CaCl2-rich brine in DJP. Based on groundwater inflow rates to DJP, we estimate that even the most concentrated brines in DJP have undergone closed-basin evaporation for less than a year. To explain the observed lack of Mg2+ and K+ accumulation in DJP over time, and the surprisingly young age for the brines, we deduce that DJP is a localized upwelling from a regional groundwater flow-through system in which evaporated DJP brines are recycled back into the subsurface over yearly timescales. The existence of a regional groundwater flow system beneath DJP has implications for water and solute budgets in cold desert ecosystems, and may provide clues for the formation of groundwater and aqueous flows on Mars.

  10. Chemical Characterization, Antileishmanial Activity, and Cytotoxicity Effects of the Essential Oil from Leaves of Pluchea carolinensis (Jacq.) G. Don. (Asteraceae).

    Science.gov (United States)

    García, Marley; Scull, Ramón; Satyal, Prabodh; Setzer, William N; Monzote, Lianet

    2017-09-01

    Current strategies to control leishmaniasis are mainly based on chemotherapy. However, none of the available drugs can be considered to be ideal to treat this disease. Because of the hydrophobic nature and bioactivities of their components, essential oils (EOs) can be considered as important sources for developing agents against intracellular pathogens, such as Leishmania parasites. In this study, we report the chemical characterization, antileishmanial activities, and cytotoxicity effect of the EO from Pluchea carolinensis (Jacq.) G. Don. (Asteraceae). Chemical analysis revealed that EO from aerial part from P. carolinensis is composed of 44 compounds. The main component was selin-11-en-4α-ol, which made up 51.0%. In vitro antileishmanial studies showed that P. carolinensis EO inhibited the growth of promastigotes (IC 50  = 24.7 ± 7.1 μg/mL) and amastigotes (IC 50  = 6.2 ± 0.1 μg/mL) of Leishmania amazonensis, while cytotoxicity evaluation revealed fivefold higher values than those for the parasites. In a model of experimental cutaneous leishmaniasis in BALB/c mice, five doses of EO at 30 mg/kg by intralesional route demonstrated smaller lesion size and parasite burden (p < 0.05) compared with animals treated with Glucantime® and untreated mice. In conclusion, in vitro and in vivo results showed the potentialities of EO from P. carolinensis with the future possibility of a new alternative in the treatment for leishmaniasis. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

  11. Relationship of "don't know" responses to cancer knowledge and belief questions with colorectal cancer screening behavior.

    Science.gov (United States)

    Ellis, Erin M; Ferrer, Rebecca A; Taber, Jennifer M; Klein, William M P

    2018-04-01

    Answering "I don't know" (DK) to survey questions that assess risk perceptions is common and occurs more often among disenfranchised groups. Because these groups also are at greater disease risk, statistically omitting or recoding DK responses may disproportionately exclude or misrepresent responses from marginalized groups and misinform intervention efforts. Because little is known about how the DK response is related to health behaviors, we examined whether the relation between DK response and colorectal cancer (CRC) screening behavior differed, depending on the construct queried (knowledge vs. beliefs). Data from the Awareness and Beliefs about Cancer survey of U.S. adults aged 50 years or older (N = 1406) were used. Cancer symptom knowledge, cancer beliefs, and CRC screening history were assessed. DK response options were not offered but were recorded if spontaneously provided. Logistic regression tested whether DK response on knowledge and belief scales were associated with CRC screening. Adjusting for demographic factors, responding DK on ≥1 belief item was associated with lower odds of having been screened for CRC in the last 5 years, p DK response on ≥1 knowledge item was unassociated with screening, p = .48. DK responders to belief items were even less likely to have been screened than participants with negative beliefs about cancer, p = .011. DK responses are differentially associated with CRC screening, depending on the construct queried, suggesting different mechanisms may underlie DK responding or its relationship with screening. Addressing construct-specific causes of DK response may improve survey research and the interventions based on them. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  12. A NEW MODULA TYPO-DIMENSIONAL, CONSTRUCTIVE AND FUNCTIONAL CONCEPT OF VIVA DON EXPERT® FLOATABLE FISH CAGES FOR INTENSIVE AQUACULTURE IN INLAND WATERS

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    D. ONEA

    2009-10-01

    Full Text Available This scientific work presents succinct information about the trials which takes place between 2005-2009 in Constanta (fish farm Canalul Rompetrol. This trials includes the fish farming in cages and leads to finishing off and elaboration of a new modular typo-dimensional, constructive and functional concept of viva don Expert® floatable fish cages for intensive aquaculture in inland waters from Romania like an efficient solution for the qualitative and quantitative increase of local fish production’s (by water volume optimizations, plants, fish farms and technologies optimizations.

  13. El inicio del juicio de residencia a don Alonso de Granada Venegas (Ocaña, Toledo, 1597) : algunas notas sobre su procedimiento

    OpenAIRE

    González Peinado, Carmen

    2010-01-01

    El artículo se centra en el inicio del juicio de residencia a don Alonso de Granada Venegas, noble de ascendencia nazarí, gobernador de la provincia de Castilla la Mancha y Ribera del Tajo perteneciente a la Orden Militar de Santiago desde 1594 a 1597, así como a los oficiales públicos y del concejo de Ocaña, sede de gobernación. La residencia tiene su especificidad propia en tierras de órdenes militares y refleja la problemática existente en torno a este cont...

  14. El inicio del juicio de residencia a donAlonso de Granada Venegas (Ocaña,Toledo, 1597) : algunas notas sobresu procedimiento

    OpenAIRE

    Carmen González Peinado

    2010-01-01

    El artículo se centra en el inicio del juicio de residencia a don Alonso de Granada Venegas, noble de ascendencia nazarí, gobernador de la provincia de Castilla la Mancha y Ribera del Tajo perteneciente a la Orden Militar de Santiago desde 1594 a 1597, así como a los oficiales públicos y del concejo de Ocaña, sede de gobernación. La residencia tiene su especificidad propia en tierras de órdenes militares y refleja la problemática existente en torno a este control, que adquiere especial releva...

  15. The application of business models to medical research: interviews with two founders of directed-philanthropy foundations. Interview with Scott Johnson and Don Listwin by Kathryn A. Phillips.

    Science.gov (United States)

    Scott, Johnson; Listwin, Don

    2007-01-01

    A new trend in research funding has emerged: directed philanthropy, in which the donor plays an active, hands-on role in managing the research by applying a "business model." Although such efforts now represent only a small portion of foundation funding, they have potentially far-reaching implications because (1) the approach of using a business model is being applied more broadly and (2) the success or failure of these efforts may portend the fate of larger translational efforts. The author conducted interviews with Scott Johnson of the Myelin Repair Foundation and Don Listwin of the Canary Foundation in the fall of 2006.

  16. Una aproximación biográfica a don Fermín José Fuero: obispo de Chiapas

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    David Martínez Vellisca

    2006-04-01

    Full Text Available A partir de un minucioso trabajo de archivo, y con el propósito de contribuir a salvaguardar la memoria histórica de Chiapas, en este texto se explora la vida peninsular de quien fuera obispo de Chiapa y Soconusco, don Fermín José Fuero Gómez, natural de la villa de Cañizares (Cuenca, quien fue preconizado el 18 de julio de 1795 y consagrado en Guatemala el 11 de septiembre de 1796.

  17. Chemical composition, plant genetic differences, and antifungal activity of the essential oil of Helichrysum italicum G. Don ssp. microphyllum (Willd) Nym.

    Science.gov (United States)

    Angioni, Alberto; Barra, Andrea; Arlorio, Marco; Coisson, Jean Daniel; Russo, Maria T; Pirisi, Filippo M; Satta, Maurizio; Cabras, Paolo

    2003-02-12

    The chemical composition of the essential oil of the Sardinian dwarf curry plant [Helichrysum italicum G. Don ssp. microphyllum (Willd) Nym] was studied. Genetic analysis suggested the presence of two chemotypes; morphological and chemical differences confirmed the presence of two chemotypes (A and B). The maximum yields were 0.18 and 0.04% (v/w) for flowering tops and stems, respectively. The concentrations of nerol and its esters (acetate and propionate), limonene, and linalool reach their highest values during the flowering stage both in flowers and in stems. Besides the essential oil, type B showed an interesting antifungal activity.

  18. Don Fernando José López de Cárdenas, descubridor del Arte Rupestre Esquemático (1783

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    Gratiniano NIETO GALLO

    2009-12-01

    Full Text Available Fue en 1783 cuando en realidad podemos decir que comienza la Historia del Arte Rupestre esquemático peninsular con el descubrimiento que de él hizo don Fernando José López de Cárdenas, en la Peña Escrita y en La Batanera de Fuencaliente, noticia de la que dio puntual referencia al Conde de Floridablanca con quien mantenía correspondencia regular en su calidad de pensionado que era de S.M. para colaborar en la recogida de minerales para el Real Gabinete de Historia Natural.

  19. ¿Locos o simplemente excéntricos? Observaciones acerca de la figura del loco en la literatura alemana a partir de su relación con el personaje de don Quijote

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    Isabel Hernández

    2007-12-01

    Full Text Available This article intends to call attention to the close relationship which exists between the figure of Don Quixote and the marginal characters and assorted weirdoes who appear in German literature during the 18th and 19th centuries. The analysis of the concept of madness in several texts from the late Middle Ages and the Baroque will enable us, on the one hand, to see how the publication of Cervantes’ novel and the consequent changes in society transformed this concept; and, on the other hand, to determine the importance of the idea of insanity for German letters, stressing the decisive role played by Don Quixote therein.

  20. Del que olvidó la muger te diré la fazaña’. La historia de don Pitas Pajas desde el Libro de buen amor (estr.474-484) hasta nuestros días

    OpenAIRE

    Lacarra, María Jesús

    2007-01-01

    En el estudio se inserta el cuento de don Pitas Payas en la amplia tradición de cuentos medievales de adulterio y se subrayan sus rasgos cómicos. Pese a que no contemos con antecedentes escritos, la localización de una versión oral asturiana y la pervivencia del motivo central en una anécdota narrada por Picasso permite aventurar la hipótesis de que Juan Ruiz reelaborara algún cuento folclórico. This paper places the short story of don Pitas Payas in the broad tradition of adultery mediev...

  1. La última curiosidad filológica de Don José Fradejas Lebrero: la voz «rera» del "Libro de vita beata" de Juan de Lucena (a modo de necrológica)

    OpenAIRE

    Gómez Redondo, Fernando

    2011-01-01

    Esta nota rinde homenaje a don José Fradejas Lebrero, fallecido en diciembre de 2010, reconstruyendo desde una conversación telefónica la que pudo ser su última pesquisa filológica: averiguar el significado de la voz «rera» en el "Libro de vita beata" de Juan de Lucena. This note pays homage to don José Fradejas Lebrero, who died in December 2010, rebuilt from a telephone conversation that could be his last philological research: find the meaning of the word «rera» in the ...

  2. Generation and analysis of expressed sequence tags from six developing xylem libraries in Pinus radiata D. Don

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    Dillon Shannon K

    2009-01-01

    Full Text Available Abstract Background Wood is a major renewable natural resource for the timber, fibre and bioenergy industry. Pinus radiata D. Don is the most important commercial plantation tree species in Australia and several other countries; however, genomic resources for this species are very limited in public databases. Our primary objective was to sequence a large number of expressed sequence tags (ESTs from genes involved in wood formation in radiata pine. Results Six developing xylem cDNA libraries were constructed from earlywood and latewood tissues sampled at juvenile (7 yrs, transition (11 yrs and mature (30 yrs ages, respectively. These xylem tissues represent six typical development stages in a rotation period of radiata pine. A total of 6,389 high quality ESTs were collected from 5,952 cDNA clones. Assembly of 5,952 ESTs from 5' end sequences generated 3,304 unigenes including 952 contigs and 2,352 singletons. About 97.0% of the 5,952 ESTs and 96.1% of the unigenes have matches in the UniProt and TIGR databases. Of the 3,174 unigenes with matches, 42.9% were not assigned GO (Gene Ontology terms and their functions are unknown or unclassified. More than half (52.1% of the 5,952 ESTs have matches in the Pfam database and represent 772 known protein families. About 18.0% of the 5,952 ESTs matched cell wall related genes in the MAIZEWALL database, representing all 18 categories, 91 of all 174 families and possibly 557 genes. Fifteen cell wall-related genes are ranked in the 30 most abundant genes, including CesA, tubulin, AGP, SAMS, actin, laccase, CCoAMT, MetE, phytocyanin, pectate lyase, cellulase, SuSy, expansin, chitinase and UDP-glucose dehydrogenase. Based on the PlantTFDB database 41 of the 64 transcription factor families in the poplar genome were identified as being involved in radiata pine wood formation. Comparative analysis of GO term abundance revealed a distinct transcriptome in juvenile earlywood formation compared to other stages of

  3. Mycological analysis of cereal samples and screening of Fusarium strains' ability to form deoxynivalenole (DON) and zearalenone (ZEA) mycotoxins--a pilot study.

    Science.gov (United States)

    Kłyszejko, Adriana; Kubus, Zaneta; Zakowska, Zofia

    2005-01-01

    Filamentous fungi are cosmopolitan microorganisms found in almost all environments. It should be pointed out that occurance of moulds on food or feed may cause health disorders in humans and animals. Mycoflora appears as a source of toxic methabolites, mycotoxins, which hepatotoxic, genotoxic, nefrotoxic and carcinogenic abilities were already proven in several studies. Hense mycological analysis of cereal grains raises as an important manner in evaluation of food and feed health features. Among the most frequent cereal contaminants Alternaria, Aspergillus, Fusarium and Penicillium strains are mentioned. Due to their ability to grow on cereals during both its field growth and storage, Fusarium moulds occure to be an important contamination factors in food and feed industry. In this study Fusarium strains isolates from wheat and maize were examined in order to recognize their abilities to produce two toxins: zearalenon (ZEA) and deoxynivalenole (DON). Mycological analysis shown differentiation within fungal microflora occuring in samples of different storage conditions, where Fusarium strains represented aproximately 20-70% of all mould species present. In purpose of Fusarium strains species evaluation, isolates were mycologically analysed. In the second step of the project, toxicological screening of isolates was performed using Thin Liquid Chromatography (TLC) evaluating toxigenic potential of single strains' production of ZEA and DON. This data gives the possibility of pointing the most toxigenic strains and also shows differentiations in their occurance in cereals. This paper presents introductory research data, which can be useful in recognition of cereal contamination with moulds and their toxic methabolites.

  4. [Foods related to the novel 'don quixote de la mancha'. did they follow the healthy nutritional recommendations which are advised nowadays?].

    Science.gov (United States)

    Carbayo Herencia, Julio A

    2015-01-01

    It is known that Miguel de Cervantes's novel 'Don Quixote de La Mancha' has done and is still doing a great contribution to the universal literature. A book that has reached such category and grows in number of its readers, shows multiple dimensions for its study. One of them is nutrition. One of the aims of this study has been to value and expound, according to their own nutrients, the kinds of food cited in 'The Quixote' and in the times of Cervantes. This has allowed the comparison made between ways of nutrition in La Mancha and in Catalonia, as well as the regions situated at the beginning and end of the itinerary covered by its main characters Don Quixote and Sancho Panza. The evaluation of the nutrients in the middle part of the itinerary, placed mainly in Aragón, has not been considered in this study. Another purpose has been to check if these nutrients followed the current recommendations of the Spanish Society of Arteriosclerosis and other valid agreements at the moment. Copyright © 2015 Sociedad Española de Arteriosclerosis. Published by Elsevier España. All rights reserved.

  5. A new protoberberine alkaloid from Meconopsis simplicifolia (D. Don) Walpers with potent antimalarial activity against a multidrug resistant Plasmodium falciparum strain.

    Science.gov (United States)

    Wangchuk, Phurpa; Phurpa, Wangchuk; Keller, Paul A; Pyne, Stephen G; Lie, Wilford; Willis, Anthony C; Rattanajak, Roonglawan; Kamchonwongpaisan, Sumalee

    2013-12-12

    The aerial components of Meconopsis simplicifolia (D. Don) Walpers are indicated in Bhutanese traditional medicine for treating malaria, coughs and colds, and the infections of the liver, lung and blood. This study is to validate the ethnopharmacological uses of this plant and also identify potent antimalarial drug leads through bioassays of its crude extracts and phytochemical constituents. Meconopsis simplicifolia (D. Don) Walpers was collected from Bhutan and its crude MeOH extract was subjected to acid-base fractionation. Through repeated extractions, separations and spectroscopic analysis, the alkaloids obtained were identified and tested for their antimalarial and cytotoxicity activities. Phytochemical studies resulted in the isolation of one new protoberberine type alkaloid which we named as simplicifolianine and five known alkaloids: protopine, norsanguinarine, dihydrosanguinarine, 6-methoxydihydrosanguinarine and oxysanguinarine. Among the five of the alkaloids tested, simplicifolianine showed the most potent antiplasmodial activities against the Plasmodium falciparum strains, TM4/8.2 (chloroquine-antifolate sensitive strain) and K1CB1 (multidrug resistant strain) with IC50 values of 0.78 μg/mL and 1.29 μg/mL, respectively. The compounds tested did not show any significant cytotoxicity activities against human oral carcinoma KB cells and normal Vero cells of African kidney epithelial cells. This study validated the traditional uses of the plant for the treatment of malaria and identified a new alkaloid, simplicifolianine as a potential antimalarial drug lead. © 2013 Published by Elsevier Ireland Ltd.

  6. En un lugar del aula… De lo que le sucedió a don Quijote en una clase de E/LE

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    Luz Celestina Souto

    2017-11-01

    Full Text Available Resumen: El presente trabajo tiene como objetivo mostrar una vía para la lectura de El ingenioso hidalgo don Quijote de la Mancha en el aula de E/LE. La propuesta se realizará a través de una selección de recursos y actividades sobre el clásico de Cervantes. Las preguntas desde las cuales se parte para el planteamiento son: ¿Qué es un clásico? ¿Por qué leer a Cervantes en la clase de E/LE? ¿Cómo leerlo? ¿Qué ventajas tiene El Quijote en el siglo xxi para quienes tienen el español como segunda lengua? Palabras Clave: Siglo de Oro, Quijote, clase de E/LE, literatura   Abstract: The present work aims to show a way to read El ingenioso hidalgo don Quijote de la Mancha in the E/LE class. The proposal is made through a selection of resources and activities about Cervantes. The questions we ask are: what is a classic? Why read Cervantes in E/LE class? How to read it? What are advantages of  El Quijote in the 21st century for those who have Spanish as a second language? Keywords: Spanish Golden Age, Quixote, E/LE class, literature

  7. Dealing with Don Juan’s Legacy: Rebellion and Inheritance in Lídia Jorge’s O vale da paixão

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    Sebastian Patron Saade

    2016-04-01

    Full Text Available This article analyzes how Lídia Jorge’s nameless woman narrator in O vale da paixão reconstructs through a story of resistance the legacy of her donjuanesque father/uncle. Dealing with the father’s legacy becomes a priority for a narrator who wishes both to affirm her feminine identity and appropriate her father’s memory. However, remembrance is not devoid of perils. To rescue her father’s life from slander, the narrator must find ways to reinterpret the myth of the rebellious, globetrotter womanizer he impersonates in the traditional patriarchal unit. Using Jacques Lacan writings on drives and Alenka Zupančič’s reading of Don Juan, I will show how Lídia Jorge’s narrative rewriting of the myth of Don Juan disrupts the patriarchal system of values from which it draws its strength.This article is published under a CC-BY license https://creativecommons.org/licenses/by/3.0/

  8. América en la librería de don Lorenzo Ramírez de Prado, Consejero de Indias

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    Nieves Pena Sueiro

    2013-12-01

    Full Text Available El estudio de inventarios de bibliotecas del Siglo de Oro resulta de gran importancia para aquellos que se interesan por la cultura áurea, pues desvela datos sobre sus poseedores; también sobre lecturas, obras, ejemplares, etc., que de otra manera no podríamos conocer. Una de las bibliotecas más importantes del siglo XVII fue la de don Lorenzo Ramírez de Prado, erudito y bibliófilo, que reunió en su casa madrileña por lo menos unos 8.951 volúmenes. Quizás la especial relación que tuvo don Lorenzo con América a lo largo de su vida –fue ahijado del humanista Pedro de Valencia, cronista de Indias; fue Consejero de Indias desde 1626 hasta su muerte, como también lo fue su hermano Alonso; otro de sus hermanos, Marcos, fue obispo de Michoacán, etc.–, influyó en que entre los fondos de su biblioteca se encuentren las principales obras de tema americano y algunas editadas en el Nuevo Mundo. En este trabajo pretendemos, tras el examen exhaustivo del inventario, ofrecer una relación de los registros del fondo americano (tema americano y obras impresas en América que existían en la librería en el momento en que se inventarió, seguido del análisis y las conclusiones de este. The study of library inventories of the Golden Age is of great interest to those who study the culture of this period, as it reveals much about their owners, and also about readings, plays, copies, etc. about which otherwise we would not know. One of the most important libraries of the seventeenth century was that of Don Lorenzo Ramirez de Prado, erudite and bibliophile, who collected in his Madrid home at least 8,951 volumes. Don Lorenzo was godson of the humanist Pedro de Valencia, chronicler of the Indies, he was Counselor of the Indies from 1626 until his death, as was his brother Alonso; another brother, Marcos, was Bishop of Michoacan. Perhaps the special relationship that Don Lorenzo had with America throughout his life was the reason that among the

  9. ESE MARAVILLOSO DON

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    YELKA CECILIA DARISIC

    2015-03-01

    Full Text Available Muchos consideran que el poder mueve el mundo,  que el dinero permite la evolución,  que la materia prima es el corazón de todo aquello  que el hombre ha creado, pero realmente podríamos decir  que la imaginación y la fantasía son vida,  que son ese mecanismo mágico que nos permite  incluso aquello que el hombre aún no ha logrado crear.

  10. La gracia del don

    OpenAIRE

    González, A.M. (Ana Marta)

    2016-01-01

    Que la gratitud pueda ser una obligación es algo que muchas veces se pasa por alto en una sociedad que apenas es consciente de sus deudas- como es patente por los casos de corrupción que nos rodean- y mucho menos de las deudas de gratitud.

  11. Hotel Don Pepe. Marbella

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    Población, Eleuterio

    1965-07-01

    Full Text Available This splendid building, located at «Las Merinas», is a new source of interest in the beautiful Costa del Sol. It has been made with the most modern materials and techniques. It has an outstanding view over the sea and it has seven standardized floor levels occupied by single rooms, whilst other parts of the building are taken up with small apartments. The recreation zone includes a bar, swimming pools for children and adults, and a cabaret. The ground floor has a main entrance hall, reception offices, shopping corridor, great hall, tea room, and bar. The second floor has a breakfast room, connecting two banqueting halls, hairdresser's, sauna baths, gymnasium, administrative offices, and the manager's flat. The services zone comprises the kitchen, a dining room for various members of the senior staff, post office, laundry, and other standard facilities. The celler serves as a general store and also as wine storage. This hotel has a most impressive functional aspect, and sets a new standard of comfort and luxury for the benefit of tourists who visit this fashionable and picturesque part of the Mediterranean coast.Este espléndido edificio, situado en la finca «Las Merinas», es un atractivo más de la bellísima Costa del Sol malagueña. Se ha instalado de acuerdo con los más modernos materiales y técnicas, disfrutando de bellas vistas hacia el mar, y dispone de: un bloque con siete plantas-tipo de habitaciones, otro de apartamentos auxiliares de pequeña altura, y la zona de recreo, con bar, piscinas para niños, nadadores y saltos, y sala de fiestas. La planta baja aloja: el acceso principal, recepción, conserjería, galería comercial, gran hall, salón de té, bar, etc. La entreplanta comprende: el comedor de desayunos, en conexión con dos comedores para banquetes; peluquerías, sauna, gimnasio, administración y vivienda del director, aparte de la zona de servicios, con cocina, comedores varios de jefes, personal, correos, lavandería, etc. El sótano alberga: las bodegas, almacenes e instalaciones. Este hotel, de notable belleza, era necesario para satisfacer las exigencias de confort de la clase turística más selecta, abriendo un nuevo campo a esta pintoresca costa mediterránea.

  12. Fernando Bouza Álvarez, «Dásele licencia y privilegio». Don Quijote y la aprobación de libros en el Siglo de Oro

    Directory of Open Access Journals (Sweden)

    Gonzalo Pontón

    2013-05-01

    Full Text Available Review of Fernando Bouza Álvarez, «Dásele licencia y privilegio». Don Quijote y la aprobación de libros en el Siglo de Oro, Akal, Madrid, 2012, 256 pp. ISBN: 978-84-460-3228-1.

  13. Más allá de la novela realista social: el proyecto destructivo de "Tiempo de silencio" (1961) de Luis Martín-Santos y "Don Julián" (1970) de Juan Goytisolo

    OpenAIRE

    Jordana Darder, Marta

    2018-01-01

    "Tiempo de silencio" (1961) de Luis Martín-Santos y "Reivindicaciones del conde Don Julián" (1970) de Juan Goytisolo son dos novelas de un fuerte compromiso político pero que se desmarcan de los caminos tradicionales del arte compro

  14. Don't Just Sit There - Do Something!: Engaging and Empowering U.S. Adults Through Short, Funny, Internet Videos About Climate Change

    Science.gov (United States)

    Portlock, J.; Laird, H.

    2015-12-01

    Communitopia, a 501(c)3 organization, uses humor, new media, and the short video format to engage and empower audiences and improve climate literacy. Our main project, the Don't Just Sit There - Do Something! video series (http://djst.tv), takes the complex subject of climate science, breaks it down into digestible nuggets of short, funny video, and couples it with easy actions viewers can take to make a difference. The series has 25 episodes so far, and more than 80,000 views on YouTube. We are reaching our target audience of high-school-age and adult viewers in the United States (94% of viewers are known to fit this demographic). Don't Just Sit There - Do Something! uses a strategic model for breaking through the fear and dread around climate change in the general population. It uses humor, positivity and brevity to frame the issue, and gives the audience simple actions designed to empower in each self-contained episode. We approach each piece of the climate puzzle with scientific rigor, and cite all our sources. Our approach is light-hearted and fun, because it is a more productive way to have a conversation about tough issues than scolding and guilt. The series is ongoing, and we are always focused on climate change. To determine the efficacy of our approach and efforts, we measure video views and other metrics through our YouTube channel, compile feedback and comments through YouTube and other social media outlets, and track actions taken through web metrics (click-through rates). We are also currently working with the Behavioral and Community Health Sciences Department at the University of Pittsburgh Graduate School of Public Health to evaluate the videos' impact. From August-October 2015, we are using an online survey to evaluate the Don't Just Sit There - Do Something! series. We will assess viewers' climate change education and awareness, commitment to support action steps that alleviate climate change, and inclination to support policy action before and

  15. Suburban Soils: Are they the answer in determining factors controlling non-point-source DOC and DON in urban surface waters?

    Science.gov (United States)

    Aitkenhead-Peterson, J. A.

    2016-12-01

    Generally the quality of urban streams has been attributed to storm water runoff and sewage effluent discharge. Recent work in the upper Trinity Basin downstream from the Dallas/Fort Worth metropolis, TX concluded that sewage effluent only contributed between 1 and 35% of DOC dependent upon the population of the watershed. Change from native to urban land use increased DOC exports to between 938 - 1840 kg km-2 yr-1relative to the 517 kg km-2 yr-1 expected from native land use. Where this excess DOC might come from in an urban ecosystem was addressed in a separate study examining water extractable DOC (WEDOC) and DON (WEDON) in soils of single-family home lawns in Chicago, IL, Frederick, MD, Bryan/College Station, TX and Galveston, TX. These cities were exposed to different sources of sodium. Time of exposure to sodium was considered on the assumption that as new sub-divisions are built, new soil or turfgrass sod is introduced to the site. Exposure times were 0-5, 6-10, 11-20, 21-30 and > 30 yr. Length of exposure time of the soil to the urban environment was significant among the four cities examined for DOC (p < 0.001), DON (p < 0.001), sodium adsorption ratio (p < 0.006) but not for sodium (p = 0.08) or exchangeable sodium percent (ESP) (p = 0.09). In all cities WEDON increased with urban exposure time and in all cities except Galveston WEDOC increased with urban exposure time. Sodium, regardless of its source, explained 60% of the variance in WEDOC and 54% of the variance in WEDON across all cities (n = 136). To determine what other factors might be involved in increasing WEDOC and WEDON losses from suburban soils, backward stepwise regression models were used. Across the four cities, time of urban exposure, soil saturated hydraulic conductivity (Ksat), NO3-N, NH4-N, S, PO4-P, Na, Cu, Ca, Fe and Zn produced a significant model for WEDOC (Adjusted r2 = 0.85; p < 0.001) and Ksat, pH, NH4-N, PO4-P, S, Alkalinity and Cu produced a significant model for WEDON

  16. Antioxidant and anticholinesterase investigations of Rumex hastatus D. Don: potential effectiveness in oxidative stress and neurological disorders

    Directory of Open Access Journals (Sweden)

    Sajjad Ahmad

    2015-01-01

    Full Text Available BACKGROUND: Rumex species are traditionally used for the treatment of neurological disorders including headache, migraine, depression, paralysis etc. Several species have been scientifically validated for antioxidant and anticholinestrase potentials. This study aims to investigate Rumex hastatus D. Don crude methanolic extract, subsequent fractions, saponins and flavonoids for acetylcholinestrase, butyrylcholinestrase inhibition and diverse antioxidant activities to validate its folkloric uses in neurological disorders. Rumexhastatus crude methanolic extract (Rh. Cr, subsequent fractions; n-hexane (Rh. Hex, chloroform (Rh. Chf, ethyl acetate (Rh. EtAc, aqueous fraction (Rh. Aq, crude saponins (Rh. Sp and flavonoids (Rh. Fl were investigated against acetylcholinesterase (AChE and butyrylcholinesterase (BChE at various concentrations (125, 250, 500,1000 μg/mL using Ellman's spectrophotometric analysis. Antioxidant potentials of Rh. Sp and Rh. Fl were evaluated using DPPH, H2O2 and ABTS free radical scavenging assays at 62.5, 125, 250, 500, 1000 μg/mL. RESULTS: All the test samples showed concentration dependent cholinesterase inhibition and radicals scavenging activity. The AChE inhibition potential of Rh. Sp and Rh. Fl were most prominent i.e., 81.67 ± 0.88 and 91.62 ± 1.67 at highest concentration with IC50 135 and 20 μg/mL respectively. All the subsequent fractions exhibited moderate to high AChE inhibition i.e., Rh. Cr, Rh. Hex, Rh. Chf, Rh. EtAc and Rh. Aq showed IC50 218, 1420, 75, 115 and 1210 μg/mL respectively. Similarly, against BChE various plant extracts i.e., Rh. Sp, Rh. Fl, Rh. Cr, Rh. Hex, Rh. Chf, Rh. EtAc and Rh. Aq resulted IC50 165,175, 265, 890, 92, 115 and 220 μg/mL respectively. In DPPH free radical scavenging assay, Rh. Sp and Rh. Fl showed comparable results with the positive control i.e., 63.34 ± 0.98 and 76.93 ± 1.13% scavenging at 1 mg/mL concentration (IC50 312 and 104 μg/mL respectively. The percent ABTS

  17. Transient identification system with noising data and 'don't know' response; Sistema de identificacao de transientes com inclusao de ruidos e indicacao de eventos desconhecidos

    Energy Technology Data Exchange (ETDEWEB)

    Mol, Antonio C. de A. [Instituto de Engenharia Nuclear (IEN), Rio de Janeiro, RJ (Brazil). Div. de Confiabilidade Humana; Martinez, Aquilino S.; Schirru, Roberto [Universidade Federal, Rio de Janeiro, RJ (Brazil). Coordenacao dos Programas de Pos-graduacao de Engenharia. Programa de Engenharia Nuclear

    2002-07-01

    In the last years, many different approaches based on neural network (NN) has been proposed for transient identification in nuclear power plants (NPP). Some of them focus the dynamic identification using recurrent neural networks however, they are not able to deal with unrecognized transients. Other kind of solution uses competitive learning in order to allow the 'don't know' response. In this case dynamic, dynamic features are not well represented. This work presents a new approach for neural network based transient identification which allows either dynamic identification and 'don't know'response. Such approach uses two multilayer neural networks trained with backpropagation algorithm. The first one is responsible for the dynamic identification. This NN uses, a short set (in a movable time window) of recent measurements of each variable avoiding the necessity of using starting events. The other one is used to validate the instantaneous identification (from the first net) through the validation of each variable. This net is responsible for allowing the system to provide 'don't know' response. In order to validate the method a NPP transient identification problem comprising 15 postulated accidents, simulated for a pressurized water reactor, was proposed in the validation process it has been considered noising data in other to evaluate the method robustness. Obtained results reveal the ability of the method in dealing with both dynamic identification of transients and correct 'don't know' response. In order to validate the method, a NPP transient identification problem comprising 15 postulated accidents simulated for a pressurized water reactor, was proposed in the validation process it has been considered noising data in order to evaluate the method robustness. Obtained results reveal the ability of the method in dealing with both dynamic identification of transients and correct 'don't know

  18. Density determination in Pino Radiata (D.Don) samples using 59.5 keV gamma radiation attenuation; Determinacion de densidad en muestras de Pino Radiata (D. Don) mediante atenuacion de radiacion gamma de 59.5 KeV

    Energy Technology Data Exchange (ETDEWEB)

    Dinator, Maria I; Morales, Jose R; Aliaga, Nelson [Chile Univ., Santiago (Chile). Dept. de Fisica; Karsulovic, Jose T; Sanchez, Jaime; Leon, Adolfo [Chile Univ., Santiago (Chile). Dept. de Tecnologia de la Madera

    1997-12-31

    A non destructive method to determine wood samples density is presented. The photon mass attenuation coefficient in samples of Pino radiata (D.Don) was measured at 59.5 keV with a radioactive source of Am-241. The value of 0.192 {+-} 0.002 cm{sup 2}/g was obtained with a gamma spectroscopy system and later used on the determination of the mass density in sixteen samples of the same species. Comparison of these results with those of gravimetric method through a linear regression showed a slope of 1.001 and a correlation factor of 0.94. (author). 3 refs., 4 figs.

  19. The Delusion of Enchantment in Miguel Cervantes’s Don Quixote and William Shakespeare’s Midsummer Night’s Dream

    Directory of Open Access Journals (Sweden)

    Kodó Krisztina

    2017-12-01

    Full Text Available The aim of the present article is to investigate the conceptual framework of magic and enchantment in the works of Miguel Cervantes de Saavedra and William Shakespeare. The works chosen for this comparative study are Don Quixote and Midsummer Night’s Dream. Shakespeare and Cervantes portray an ironic vision that may seem comic and grotesque on the surface, but in fact shows a violent and malign world. The portrayal of fantasy and realism parallel with the delusionary aspects of enchantment create an interplay between the ironic mockery and reality as seen through the experiences of the characters themselves. The delusions of enchantment experienced by the protagonists present a flawed world where jealousy, greed and corruption prevail.

  20. El arzobispo don Pedro de Castro Cabeza de Vaca y Quiñones y la influencia del Sacro Monte en el desarrollo inmaculista en Granada.

    Directory of Open Access Journals (Sweden)

    José Antonio Peinado Guzmán

    2015-12-01

    Full Text Available The figure of archbishop don Pedro de Castro was extremely important for the development of immaculist devotion in Granada in the 16th century and beginning of the 17th century. In the wake of the famous discoveries of the Sacro Monte, it will produce an evolution of this belief in land Granada at the request of this prelate, who took the issue as one of his personal priorities in his episcopate. Intelligent handling of the issue by the Archbishop, while the findings of the Sacro Monte were subsequently convicted of Rome, eventually landing in the erection of the Abbey, in the ideological use of all of this, as well as the extension of the conceptionism in Granada.

  1. Human radiation studies: Remembering the early years: Oral history of cell biologist Don Francis Petersen, Ph.D., conducted November 29, 1994

    International Nuclear Information System (INIS)

    1995-08-01

    This report is a transcript of an interview of Dr. Don Francis Petersen by representatives of the US DOE Office of Human Radiation Experiments. Dr. Petersen was selected for this interview because of his long research career at Los Alamos and his knowledge of the Atomic Energy Commission's biomedical program. Dr. Petersen did not personally conduct research on human subjects. After a brief biographical sketch Dr. Petersen discusses his remembrances of the early use of radionuclides as biological tracers, aspects of nuclear weapons testing in the 1940's and 1950's including fallout studies, the means by which research projects were approved, use of humans in the whole-body counter, and the Health Division Biomedical responsibilities

  2. Efeito do volume de tubetes e tipos de substratos na qualidade de mudas de cryptomeria japonica (l.f. d. don.

    Directory of Open Access Journals (Sweden)

    Constâncio Bernardo dos Santos

    2000-01-01

    Full Text Available Cryptomeria japonica (L. F. D. Don. is a species of great potential for planting in elevated and cold regions of Brazil. It is remarkable for its fast growth, good adaptation to the climate and soil of Southern Brazil, and it also shows a good response to silvicultural technologies. In addition, it is notable for the quality and diversity of its raw material usage for the industries of pulp and paper, plywood, construction of houses, furniture, boats, ships, etc. The experimental plan was bifactorial in the entirely randomized design with 8 treatments, 5 repetitions with 40 seedlings per treatment. The results indicated that for the production of seedlings of this species, the substrate soil + vermiculite showed the best development of the seedlings in 120 cm3 containers.

  3. Green synthesis and characterization of zinc oxide nanoparticle using insulin plant (Costus pictus D. Don) and investigation of its antimicrobial as well as anticancer activities

    Science.gov (United States)

    Suresh, Joghee; Pradheesh, Ganeshan; Alexramani, Vincent; Sundrarajan, Mahalingam; Hong, Sun Ig

    2018-03-01

    In this work we aim to synthesize biocompatible ZnO nanoparticles from the zinc nitrate via green process using leaf extracts of the Costus pictus D. Don medicinal plant. FTIR studies confirm the presence of biomolecules and metal oxides. X-ray diffraction (XRD) structural analysis reveals the formation of pure hexagonal phase structures of ZnO nanoparticles. The surface morphologies of ZnO nanoparticles observed under a scanning electron microscope (SEM) suggest that most ZnO crystallites are hexagonal. EDX analysis confirms the presence of primarily zinc and oxygen. TEM images show that biosynthesized zinc oxide nanoparticles are hexagonal and spherical. The plausible formation mechanisms of zinc oxide nanoparticles are also predicted. The biosynthesized zinc oxide nanoparticles exhibit strong antimicrobial behavior against bacterial and fungal species when employing the agar diffusion method. Synthesized ZnO nanoparticles exhibit anticancer activity against Daltons lymphoma ascites (DLA) cells as well as antimicrobial activity against some bacterial and fungal strains.

  4. La elocuencia del embajador: don Juan Antonio de Vera y Zúñiga y las «Orationi militari» de Remigio Nannini

    OpenAIRE

    Pineda, Victoria

    2015-01-01

    El libro de diplomacia El embaxador (1620), escrito en forma de diálogo por don Juan Antonio de Vera y Zúñiga, se convirtió tras su publicación en uno de los tratados más influyentes de su género en toda Europa. El contenido y la filiación política del diálogo han sido mencionados con frecuencia en los estudios sobre filosofía política y sobre asuntos de diplomacia, pero poco se ha dicho acerca de las posibles lecturas que habrían influido en la composición de El embajador en lo que atañe al ...

  5. Effet de la cuisson et du séchage des noix de karité (Butyrospermum parkii (G. Don Kotschy sur la qualité du beurre

    Directory of Open Access Journals (Sweden)

    Womeni, HM.

    2006-01-01

    Full Text Available Effect of Cooking and Drying of Shea Nuts (Butyrospermum parkii (G. Don Kotschy on the Quality of Butter. Cooking time and drying temperature of shea nuts (Butyrospermum parkii which protect the quality of the butter were determined. A cooking of nuts in boiling water for 100 to 120 minutes followed by the drying at 60-70 °C allows to obtain a butter with an acidity lower than 0.3% oléic acid, a peroxide value close to 1 meq O2/kg, a high content of unsaponifiable matters (> 5% containing more than 80% of triterpenic alcohols. Thus, the cooking of shea nuts appears as an important operation for the process of the shea butter extraction.

  6. Cine, literatura y mito: Don Quijote en el cine, más allá de la adaptación

    Directory of Open Access Journals (Sweden)

    Pardo García, Pedro Javier

    2011-04-01

    Full Text Available This paper discusses Don Quixote’s presence in film, but in terms of the myth rather than the book, an approach which goes beyond adaptation and opens up the field of study in a significant way. In so doing it proposes a tentative but coherent description of the quixotic myth or narrative pattern as that of the inadequate and romantic imitator/reader of fiction, which is the point of departure for the elaboration of an initial corpus of quixotic movies. The protagonists of these films are frustrated imitators of cinematographic models, female Quixotes who romanticize reality and heroes who are Quixotic because they are not fit for the heroic task they have undertaken. In order to illustrate this deep penetration of the myth into the cinematic medium, a recent example in Spanish cinema will be examined, The Heart of the Warrior (El corazón del guerrero, 2000, a film directed by Daniel Monzón, where these several varieties are at work in a combined and crystal clear way. Our survey will allow us to make a series of distinctions which organise and structure the different kinds of relationship between Don Quixote and film (Cervantean, quixotic and quixotish film and, finally, to draw a series of theoretical conclusions which can be applied to the comparative study of film and literature.

    Este trabajo se ocupa de la presencia en el cine de Don Quijote, pero no del libro sino del mito, una perspectiva que va mucho más allá de la adaptación y abre considerablemente el campo de estudio. Para ello, se propone una descripción que se sabe provisional pero intenta ser rigurosa del mito o el patrón narrativo quijotesco como el del lector/imitador romántico e inadecuado de ficción, a partir de la cual se puede elaborar un primer corpus de películas quijotescas. En él se incluyen las protagonizadas por imitadores fallidos de modelos cinematográficos, por Quijotes femeninos que romantizan la realidad y por diversos tipos de héroes que son

  7. El sueño caballeresco. De la caballería de papel al sueño real de don Quijote

    OpenAIRE

    Cátedra, Pedro M.

    2007-01-01

    El Quijote es difícilmente comprensible sin atender al contexto en el más amplio sentido del término. Si es cierto que, para don Quijote, como lector y actor, la caballería y sus códigos eran una realidad de signos, no lo es menos que en tiempos de Cervantes aún la caballería tiene una fuerza representativa a la que hay que reconocerle mucho más que una pura representación desgastada y ya en franca ruina y pérdida. En este libro se estudia la repercusión del sueño caballeresco en el siglo XVI...

  8. Phytochemical study of Helichrysum italicum (Roth) G. Don: Spectroscopic elucidation of unusual amino-phlorogucinols and antimicrobial assessment of secondary metabolites from medium-polar extract.

    Science.gov (United States)

    D'Abrosca, Brigida; Buommino, Elisabetta; Caputo, Pina; Scognamiglio, Monica; Chambery, Angela; Donnarumma, Giovanna; Fiorentino, Antonio

    2016-12-01

    Three unusual amino-phloroglucinols, named helichrytalicines A-C, along with seventeen known compounds including acetophenones, tremetrone derivatives, low-molecular weight phenols, flavonol glucosides, have been isolated from the medium-polar extract of Helichrysum italicum (Roth) G. Don, a medicinal plant typical of the Mediterranean vegetation. The structures of the compounds have been elucidated based on extensive 2D-NMR spectroscopic analyses, including COSY, TOCSY, HSQC, CIGAR-HMBC, H2BC and HSQC-TOCSY, along with Q-TOF HRMS 2 analysis. Stereostructure of the new compounds has been elucidated by Mosher's method and NOESY experiment. Antimicrobial properties against Staphylococcus epidermidis of selected compounds have been evaluated. Copyright © 2016 Elsevier Ltd. All rights reserved.

  9. Le don en retour. Quelques contes espagnols médiévaux autour du thème de l’échange

    OpenAIRE

    Darbord, Bernard

    2014-01-01

    Les collections de contes exemplaires ont souvent adopté un ordre alphabétique, facilitant ainsi l’élaboration des sermons et homélies. Parmi les motifs les plus familiers, celui du don mal payé en retour apparaît dans les rubriques traitant de l’ingratitude, mais aussi dans les textes consacrés à l’usure et à l’aumône. L’homme qui donne généreusement au pauvre, sans être rétribué par celui-ci, prête à Dieu qui remboursera au centuple. Les relations d’argent, les notions de prêt, d’intérêt, d...

  10. Human radiation studies: Remembering the early years: Oral history of cell biologist Don Francis Petersen, Ph.D., conducted November 29, 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-08-01

    This report is a transcript of an interview of Dr. Don Francis Petersen by representatives of the US DOE Office of Human Radiation Experiments. Dr. Petersen was selected for this interview because of his long research career at Los Alamos and his knowledge of the Atomic Energy Commission`s biomedical program. Dr. Petersen did not personally conduct research on human subjects. After a brief biographical sketch Dr. Petersen discusses his remembrances of the early use of radionuclides as biological tracers, aspects of nuclear weapons testing in the 1940`s and 1950`s including fallout studies, the means by which research projects were approved, use of humans in the whole-body counter, and the Health Division Biomedical responsibilities.

  11. Impact of the Swap It, Don't Stop It Australian National Mass Media Campaign on Promoting Small Changes to Lifestyle Behaviors.

    Science.gov (United States)

    O'Hara, Blythe J; Grunseit, Anne; Phongsavan, Philayrath; Bellew, William; Briggs, Megan; Bauman, Adrian E

    2016-12-01

    Mass media campaigns aimed at influencing lifestyle risk factors are one way that governments are attempting to address chronic disease risk. In Australia, a national campaign aimed at encouraging Australians to make changes in lifestyle-related behaviors was implemented from 2008 to 2011. The first phase, Measure Up (2008-2009), focused on why lifestyle changes are needed by increasing awareness of the link between waist circumference and chronic disease risk. The second phase, Swap It, Don't Stop It (2011), emphasized how adults can change their behaviors. Cross-sectional telephone surveys (after the campaign) were undertaken in July and November 2011 to evaluate the Swap It, Don't Stop It campaign and included measures of campaign awareness and lifestyle-related behavior change. Survey participants (N = 5,097) were similar across the two survey periods. Prompted campaign awareness was 62% (16% for unprompted awareness); females, younger respondents (18-44 years), those in paid employment, and those who spoke English at home were more likely to report prompted/unprompted campaign awareness. Moreover, 16% of survey respondents reported any swapping behavior in the previous 6 months, with the majority (14%) reporting only one swap; younger respondents and those in paid employment were significantly more likely to report having implemented a swapping behavior. The campaign achieved modest population awareness but demonstrated limited effect in terms of nudging behaviors. This evaluation indicates that encouraging swapping behaviors as a prelude to lifestyle change may not result from a mass media campaign alone; a comprehensive multicomponent population approach may be required.

  12. [The haplomatch program for comparing Y-chromosome STR-haplotypes and its application to the analysis of the origin of Don Cossacks].

    Science.gov (United States)

    Chukhryaeva, M I; Ivanov, I O; Frolova, S A; Koshel, S M; Utevska, O M; Skhalyakho, R A; Agdzhoyan, A T; Bogunov, Yu V; Balanovska, E V; Balanovsky, O P

    2016-05-01

    STR haplotypes of the Y chromosome are widely used as effective genetic markers in studies of human populations and in forensic DNA analysis. The task often arises to compare the spectrum of haplotypes in individuals or entire populations. Performing this task manually is too laborious and thus unrealistic. We propose an algorithm for counting similarity between STR haplotypes. This algorithm is suitable for massive analyses of samples. It is implemented in the computer program Haplomatch, which makes it possible to find haplotypes that differ from the target haplotype by 0, 1, 2, 3, or more mutational steps. The program may operate in two modes: comparison of individuals and comparison of populations. Flexibility of the program (the possibility of using any external database), its usability (MS Excel spreadsheets are used), and the capability of being applied to other chromosomes and other species could make this software a new useful tool in population genetics and forensic and genealogical studies. The Haplomatch software is freely available on our website www.genofond.ru. The program is applied to studying the gene pool of Cossacks. Experimental analysis of Y-chromosomal diversity in a representative set (N = 131) of Upper Don Cossacks is performed. Analysis of the STR haplotypes detects genetic proximity of Cossacks to East Slavic populations (in particular, to Southern and Central Russians, as well as to Ukrainians), which confirms the hypothesis of the origin of the Cossacks mainly due to immigration from Russia and Ukraine. Also, a small genetic influence of Turkicspeaking Nogais is found, probably caused by their occurrence in the Don Voisko as part of the Tatar layer. No similarities between haplotype spectra of Cossacks and Caucasus populations are found. This case study demonstrates the effectiveness of the Haplomatch software in analyzing large sets of STR haplotypes.

  13. Effects of breathing frequency and flow rate on the total inward leakage of an elastomeric half-mask donned on an advanced manikin headform.

    Science.gov (United States)

    He, Xinjian; Grinshpun, Sergey A; Reponen, Tiina; McKay, Roy; Bergman, Michael S; Zhuang, Ziqing

    2014-03-01

    The objective of this study was to investigate the effects of breathing frequency and flow rate on the total inward leakage (TIL) of an elastomeric half-mask donned on an advanced manikin headform and challenged with combustion aerosols. An elastomeric half-mask respirator equipped with P100 filters was donned on an advanced manikin headform covered with life-like soft skin and challenged with aerosols originated by burning three materials: wood, paper, and plastic (polyethylene). TIL was determined as the ratio of aerosol concentrations inside (C in) and outside (C out) of the respirator (C in/C out) measured with a nanoparticle spectrometer operating in the particle size range of 20-200nm. The testing was performed under three cyclic breathing flows [mean inspiratory flow (MIF) of 30, 55, and 85 l/min] and five breathing frequencies (10, 15, 20, 25, and 30 breaths/min). A completely randomized factorial study design was chosen with four replicates for each combination of breathing flow rate and frequency. Particle size, MIF, and combustion material had significant (P plastic aerosol produced higher mean TIL values than wood and paper aerosols. The effect of the breathing frequency was complex. When analyzed using all combustion aerosols and MIFs (pooled data), breathing frequency did not significantly (P = 0.08) affect TIL. However, once the data were stratified according to combustion aerosol and MIF, the effect of breathing frequency became significant (P plastic combustion aerosol. The effect of breathing frequency on TIL is less significant than the effects of combustion aerosol and breathing flow rate for the tested elastomeric half-mask respirator. The greatest TIL occurred when challenged with plastic aerosol at 30 l/min and at a breathing frequency of 30 breaths/min.

  14. Le savoir-faire local dans la valorisation alimentaire des fruits du safoutier (Dacryodes edulis (G. Don H.J. Lam au Cameroun

    Directory of Open Access Journals (Sweden)

    Noumi, GB.

    2006-01-01

    Full Text Available The Local Know-how in the Valorisation of (Dacryodes edulis (G. Don H.J. Lam Fruits in Cameroon. Dacryodes edulis (G. Don H.J. Lam (Burseraceae is an oleaginous plant highly appreciated in the forest zone of Cameroon. This tree yields fruits called african pear or safou, highly consumed by local populations and even abroad. African pear is at the centre of a great economic activity in the Central Africa subregion as its trade generates cash for local traders during the production period. However, the valorisation of african pear is hindered by its high perishable nature responsible for important post-harvest losses due to lack of proper post-harvest handling. Some studies addressed the problem, unfortunately, nothing was done on the local know-how which has still to be investigated. The present paper sheds light on african pear local harvesting, handling and marketing practices in Cameroon. Field surveys were carried out in different production zones in Cameroon savannah and humid forest lowlands: Adamawa, centre, east, littoral and west provinces. Results showed that african pear occupies an important place in the population daily life. This multipurpose tree specie appears to be a source of foodstuffs, cash income, drugs and wood. If, on one hand diverse strategies are developed by the population for a proper conservation of fruits, on the other hand there is not a real fruits transformation activity. Results of this study highlight the traditional know-how and bring out prospects for future works on african pear valorisation.

  15. Peut-on penser le travail par le don ? Présentation du débat Conceptualising work as a gift. Debate presentation ¿Es posible pensar el trabajo a través del don ?

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    Lionel Jacquot

    2012-12-01

    Full Text Available Depuis la parution du traité de Georges Friedmann et Pierre Naville il y a cinquante ans, la sociologie du travail a toujours cherché à comprendre, sous leurs divers aspects, toutes les communautés humaines qui se constituent à l’occasion du travail. Elle s’y est attachée en introduisant dans son champ une très riche variété de paradigmes et en acceptant par là même les conflits théoriques. C’est dans cet esprit d’ouverture et de débat que le premier dossier Chorus de la Nouvelle Revue du Travail est consacré à la mise en œuvre du paradigme du don en matière de sociologie du travail. Alain Caillé, le principal animateur du Mouvement Anti-Utilitariste en Sciences Sociales (MAUSS et Norbert Alter, le contributeur essentiel d’inspiration maussienne pour la sociologie du travail et des organisations, reviennent dans deux textes inédits sur les vertus heuristiques de la théorie du don contre-don pour appréhender le monde du travail et ses mutations. La NRT ouvre ensuite le débat avec ces deux auteurs.Since Georges Friedmann and Pierre Naville’s seminal treatise was first published 50 years ago, the sociology of work has always tried to understand the full range of human communities that arise when work occurs, under all of their different aspects. It has tried to achieve this by introducing a very wide variety of paradigms into the field and by addressing any ancillary theoretical conflicts. It is in this spirit of openness and debate that the first Chorus file in the Nouvelle Revue du Travail (NRT looks at how the gift paradigm has been implemented in the sociology of work. Alain Caillé, one of the main drivers behind the “Anti-Utilitarian Social Sciences Movement” (Mouvement anti-utilitariste en sciences sociales, MAUSS – along with Norbert Alter, a leading Maussian figurehead in the sociology of work and organisations – use two original texts to review the heuristic virtues of the gift/counter-gift theory

  16. Chemical constituents of Helichrysum italicum (Roth G. Don essential oil and their antimicrobial activity against Gram-positive and Gram-negative bacteria, filamentous fungi and Candida albicans

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    Bouzid Djihane

    2017-07-01

    Full Text Available The aerial parts of Helichrysum italicum (Roth G. Don were subjected to hydrodistillation to obtain essential oils which had been analyzed by gas chromatography and gas chromatography coupled with mass spectrometry and tested for antimicrobial activity against 12 bacteria, two yeasts and four fungi by agar diffusion method. The essential oil yielded 0.44% (v/w and 67 compounds accounting for 99.24% of the oil were identified with a high content of oxygenated sesquiterpenes (61.42%. The most oxygenated sesquiterpene compounds were α-Cedrene (13.61%, α-Curcumene (11.41%, Geranyl acetate (10.05%, Limonene (6.07%, Nerol (5.04%, Neryl acetate (4.91% and α-Pinene (3.78%. The antimicrobial activity of the essential oil was assayed by using the disk diffusion method on Escherichia coli ATCC 25922, Staphylococcus aureus ATCC 6538, Micrococcus luteus ATCC 4698, Klebsiella pneumonia ATCC 4352, Enterococcus cereus ATCC 2035, Bacillus cereus ATCC 10876, Staphylococcus epidermidis ATCC 12228, Bacillus subtilis ATCC 9372, Pseudomonas aeruginosa ATCC 27853, Enterococcus faecalis ATCC 49452, Proteus mirabilis ATCC 35659, Listeria monocytogenes ATCC 15313 and yeasts Candida albicans ATCC 10231, Saccharomyces cerevisiae ATCC 9763 and fungi, Fusarium solani var. coeruleum, Aspergillus niger, Alternaria alternata, Ascochyta rabiei. H. italicum inhibited the growth of all the tested microorganisms except three bacteria, E. coli ATCC 25922, K. pneumonia ATCC 4352 and L. monocytogenes ATCC 15313. The most sensitive bacterium was E. cereus ATCC 2035 with minimum inhibitory and bactericidal concentrations of 0.79 μg ml−1. A minimum fungistatic and fungicide concentration of 6.325 μg ml−1 and 12.65 μg ml−1 respectively was obtained with C. albicans ATCC 10231 and S. cerevisiae ATCC 9763. However the four fungi were more resistant with fungistatic minimum concentration ranging from 6.325 μg ml−1 to 50.6 μg ml−1 and a fungicide minimum

  17. Restauro storico y sacrae imagines en Évora bajo el gobierno del arzobispo don Teotonio de Braganza (1578-1602

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    Serrão, Vitor

    2016-06-01

    Full Text Available This essay focuses on the figure of D. Teotónio de Bragança, the Archbishop of Évora between 1578 and 1602, showing the importance of his building projects and artistic decorations, under the sign of Tridentine values. He adapted the principles of ‘restauro storico’ and the revitalization of ‘imagine sacrae’ in the Early Christian sanctuaries of his archdiocese. He promoted a new type of sacred architecture using artists formed in Rome, such as the architect and sculptor Pero Vaz Pereira. The art born in Évora in the late-16th century, under the sign of the Contra-Maniera, achieves a quality that rivals with that of the reign of King John III and the humanist André de Resende. Old cults and new iconographic themes emerge with D. Teotónio, such as SS. Manços, Jordão, Comba and other martyrs considered Évora-born. He ordered several works for Madrid, Rome and Florence to enrich the Cathedral and the Carthusian Monastery founded by him. Thus this period forms one of the most remarkable chapters in Portuguese Tridentine art and deserves to be properly analyzed.En este ensayo se aborda la figura de don Teotonio de Braganza (arzobispo de Évora entre 1578 y 1602 y su legado en los programas de decoración artística y en el modo como adaptó los principios tridentinos del restauro storico y la revitalización de las sacra imagines en lugares de culto paleocristiano de su archidiócesis. Durante su munus se desarrolló un nuevo tipo de arquitectura sacra gracias a la participación de artistas con formación romana, como era el caso del arquitecto y escultor Pero Vaz Pereira. El arte que vio la luz en Évora a finales del siglo XVI, bajo el signo de la Contramaniera, alcanzó un esplendor que rivalizaría con el del reinado de Juan III y del humanista André de Resende. Con don Teotonio emergen nuevos temas y cultos, como los de los santos Mancio, Jordán, Comba y otros mártires considerados ‘eborenses’. El arzobispo encarg

  18. Chemical constituents of Helichrysum italicum (Roth) G. Don essential oil and their antimicrobial activity against Gram-positive and Gram-negative bacteria, filamentous fungi and Candida albicans.

    Science.gov (United States)

    Djihane, Bouzid; Wafa, Nouioua; Elkhamssa, Soltani; Pedro, De Haro Juan; Maria, Angeles Esteban; Mohamed Mihoub, Zerroug

    2017-07-01

    The aerial parts of Helichrysum italicum (Roth) G. Don were subjected to hydrodistillation to obtain essential oils which had been analyzed by gas chromatography and gas chromatography coupled with mass spectrometry and tested for antimicrobial activity against 12 bacteria, two yeasts and four fungi by agar diffusion method. The essential oil yielded 0.44% (v/w) and 67 compounds accounting for 99.24% of the oil were identified with a high content of oxygenated sesquiterpenes (61.42%). The most oxygenated sesquiterpene compounds were α-Cedrene (13.61%), α-Curcumene (11.41%), Geranyl acetate (10.05%), Limonene (6.07%), Nerol (5.04%), Neryl acetate (4.91%) and α-Pinene (3.78%). The antimicrobial activity of the essential oil was assayed by using the disk diffusion method on Escherichia coli ATCC 25922, Staphylococcus aureus ATCC 6538, Micrococcus luteus ATCC 4698, Klebsiella pneumonia ATCC 4352, Enterococcus cereus ATCC 2035, Bacillus cereus ATCC 10876, Staphylococcus epidermidis ATCC 12228, Bacillus subtilis ATCC 9372, Pseudomonas aeruginosa ATCC 27853, Enterococcus faecalis ATCC 49452, Proteus mirabilis ATCC 35659, Listeria monocytogenes ATCC 15313 and yeasts Candida albicans ATCC 10231, Saccharomyces cerevisiae ATCC 9763 and fungi, Fusarium solani var. coeruleum , Aspergillus niger , Alternaria alternata , Ascochyta rabiei . H. italicum inhibited the growth of all the tested microorganisms except three bacteria, E. coli ATCC 25922, K. pneumonia ATCC 4352 and L. monocytogenes ATCC 15313. The most sensitive bacterium was E. cereus ATCC 2035 with minimum inhibitory and bactericidal concentrations of 0.79 μg ml -1 . A minimum fungistatic and fungicide concentration of 6.325 μg ml -1 and 12.65 μg ml -1 respectively was obtained with C. albicans ATCC 10231 and S. cerevisiae ATCC 9763. However the four fungi were more resistant with fungistatic minimum concentration ranging from 6.325 μg ml -1 to 50.6 μg ml -1 and a fungicide minimum concentration of 50

  19. N-(Pivaloyloxy)alkoxy-carbonyl Prodrugs of the Glutamine Antagonist 6-Diazo-5-oxo-l-norleucine (DON) as a Potential Treatment for HIV Associated Neurocognitive Disorders.

    Science.gov (United States)

    Nedelcovych, Michael T; Tenora, Lukáš; Kim, Boe-Hyun; Kelschenbach, Jennifer; Chao, Wei; Hadas, Eran; Jančařík, Andrej; Prchalová, Eva; Zimmermann, Sarah C; Dash, Ranjeet P; Gadiano, Alexandra J; Garrett, Caroline; Furtmüller, Georg; Oh, Byoungchol; Brandacher, Gerald; Alt, Jesse; Majer, Pavel; Volsky, David J; Rais, Rana; Slusher, Barbara S

    2017-08-24

    Aberrant excitatory neurotransmission associated with overproduction of glutamate has been implicated in the development of HIV-associated neurocognitive disorders (HAND). The glutamine antagonist 6-diazo-5-oxo-l-norleucine (DON, 14) attenuates glutamate synthesis in HIV-infected microglia/macrophages, offering therapeutic potential for HAND. We show that 14 prevents manifestation of spatial memory deficits in chimeric EcoHIV-infected mice, a model of HAND. 14 is not clinically available, however, because its development was hampered by peripheral toxicities. We describe the synthesis of several substituted N-(pivaloyloxy)alkoxy-carbonyl prodrugs of 14 designed to circulate inert in plasma and be taken up and biotransformed to 14 in the brain. The lead prodrug, isopropyl 6-diazo-5-oxo-2-(((phenyl(pivaloyloxy)methoxy)carbonyl)amino)hexanoate (13d), was stable in swine and human plasma but liberated 14 in swine brain homogenate. When dosed systemically in swine, 13d provided a 15-fold enhanced CSF-to-plasma ratio and a 9-fold enhanced brain-to-plasma ratio relative to 14, opening a possible clinical path for the treatment of HAND.

  20. Leaf blight of catharanthus roseus (l). g. don caused by macrophomina phaseolina (tassi) goid and its in vitro control through bio-pesticides

    International Nuclear Information System (INIS)

    Mridha, M.A.U.; Rehman, M.M.

    2015-01-01

    Catharanthus roseus (L.).G. Don, a highly valued medicinal plant suffers from a serious disease. A survey on the symptom and severity of the leaf blight of C. roseus was performed in the nurseries of the Institute of Forestry and Environmental Sciences (IFESCU), Bangladesh Council of Industrial Research (BCSIR) and Bangladesh Forest Research Institute (BFRI), Bangladesh. An observation was also made in the avenues and garden of King Saud University (KSU), Kingdom of Saudi Arabia. No disease was recorded in KSU, but severe infections were found in all the locations surveyed in Bangladesh. The highest infection percentage and the highest disease index were found in BCSIR nursery followed by BFRI and the lowest was recorded in IFESCU nursery. Macrophomina phaseolina (Tassi) Goid was isolated and it was proved to be pathogenic. This is the first report of leaf blight of C. roseus caused by M. phaseolina. Azadirachta indica, Ocimum sanctum Vitex negundo, Mucuna pruriens, Calotropis procera, Terminalia arjuna, Allium sativum, Zingiber officinalis and Allium cepa were used as biopesticides. Out of the nine plant species screened, T. arjuna showed the highest (58.37%) inhibition percentage which was followed by A. indica (55.72%) and the lowest (27.4%) inhibition percentage were obtained with V. negundo whereas the rest of the plant extracts showed more or less same inhibitory effect. (author)

  1. Condicionamientos internos en la variación de los pronombres personales átonos en Los hechos de Don Miguel Lucas de Iranzo

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    Francisco Díaz Montesinos

    2004-06-01

    Full Text Available The aim of this paper is to analyse the linguistic factors constraining the use of personal clitics lo(s, la(s, le(s in XVth Century Middle-Age Castilian, as revealed in the Relación de los Hechos de Don Miguel Lucas de Iranzo (1458. A multivariate analysis of data from this text shows that internal (morphological, syntactic, lexical and textual factors interact and allows us to imagine the simplest and original context where leísmo could start. A nearly categorical tendency to employ le for male referents as direct objects is developed with human antecedents and where Latin used dative case or alternated between dative and accusative case. If Latin used accusative case, occurrence of le (leísmo depends on a set of linguistic constraints whose effect is systematic and predictable, as shows a logistic regression analysis carried out in this paper. Use of le (leísmo for human antecedents is constrained by the following internal factors: etymology, the number and the clitic's position within the sentence, type of syntactic structure and the verb's tense.

  2. Don Quijote et Dulcinea, ou quand l’univers fictionnel interroge la réalité de l’amour

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    Odile Lasserre Dempure

    2009-02-01

    Full Text Available Vaste mise en miroir d’une fiction qui n’en finit pas d’interroger son rapport ambigu au réel, le chef d’œuvre de Cervantès place le mouvement dialectique entre univers fictionnel et réalité au cœur même de son écriture. Au sein de cette dialectique, l’amour multiplement fictionnel de don Quichotte pour Dulcinée joue cependant un rôle majeur que ce travail se propose d’examiner. Lieu d’épanouissement privilégié d’un questionnement du rapport entre fiction et réalité, la mise en écriture de cet amour participe en effet de la vaste entreprise de révision des concepts menée par la pensée humaniste : c’est une exploration de la notion même d’amour, de sa réalité, de sa vérité, que permet le voyage au pays de l’amour auquel le Quichotte de Cervantès invite le lecteur.

  3. DON QUIJOTE DE LA MANCHA: DIALOGISMO Y CARNAVALIZACIÓN, DIÁLOGO SOCRÁTICO Y SÁTIRA MENIPEA

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    Manuel Jofré

    2005-11-01

    Full Text Available Se discuten aquí algunas de las tesis de Mijail Bajtín en relación con la novela Don Quijote. Primero, la oposición entre novela dialógica versus novela polifónica; segundo, la pertinencia del diálogo socrático y la sátira menipea en la estructura novelesca misma; tercero, la pertinencia del monologismo en la aproximación de poética histórica; y cuarto, algunos aspectos de la carnavalización en la novelaSome of Mijail Bachtin’s theses are discussed here. First the opposition between the dialogic novel and the polyphonic; in the second place, the pertinence of Socratic dialogue and the Menippean satire in the fictional structure itself; thirdly, the pertinence of monologism in the approach to a historical poetic; and lastly, some of the aspects of carnavalization in the novel

  4. Mothers 'don't like it; never tried it': Blind Sensory Test of a Homemade Chicken Liver Baby Food, a Source of Iron, by Infants and their Mothers.

    Science.gov (United States)

    Campos, Viviani Jaques; Morais, Tania Beninga

    2015-08-01

    A homemade chicken liver baby food (CLBF) that meets infants' nutritional requirements was developed and its acceptance by children and their mothers determined. CLBF's nutritional content was determined by chemical analyses. A blind sensory test (ST) by 50 infants 7-12 months old and their mothers of CLBF and ground beef baby food (GBBF) was applied. Mothers' preferences for liver and beef, answers of an hedonic scale and infants' acceptance were investigated. CLBF met the nutritional requirements for infants. There were no significant differences in the ST between the CLBF and GBBF, either for infants or for their mothers. There was no correlation between mothers' like or dislike of liver and the ST scores. Infants tried and liked the CLBF that match dietary recommendations and could help prevent iron deficiency. Mothers, on the other hand, demonstrated an 'I don't like it; I never tried it' attitude. © The Author [2015]. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  5. Morir y matar amando: Amor de don Perlimplín con Belisa en su jardín

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    Peral Vega, Emilio

    2004-04-01

    Full Text Available «Morir y matar amando: Amor de don Perlimplín con Belisa en su Jardín» apuesta por una de las obras dramáticas lorquianas no sólo de menor presencia escénica sino también de menor bibliografía secundaria en torno a ella. Y lo hace analizando la intrincada red de influencias -desde la commedia dell'arte italiana, pasando por el teatro breve del Siglo de Oro español, para llegar al simbolismo francés- que convierte a su personaje, Perlimplín, en un ente dramático esencial, capaz de sacudirse una tradición que había hecho de sus congéneres cornudos -recordemos el Cañizares cervantino que tanto se le asemeja en un primer estadio de la pieza- unos peleles al servicio de una comicidad de guante blanco,…

  6. Inhibitory Effects of Urginea maritima (L. Baker, Zhumeria majdae Rech. F. and Wendelbo and Physalis divaricata D. Don Ethanolic Extracts on Mushroom Tyrosinase

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    Foroogh Namjoyan, Alireza Jahangiri, Mohammad Ebrahim Azemi, Hamideh Mousavi

    2016-06-01

    Full Text Available Background: Tyrosinase is a key enzyme in melanin synthesis from tyrosine. To prevent or treat pigmentation disorders, tyrosinase inhibitors have been used increasingly for medicinal and cosmetic products. The aim of this study is to evaluate inhibitory effects of Urginea maritima (L. Baker, Zhumeria majdae Rech.f. & Wendelbo and Physalis divaricata D.Don on mushroom tyrosinase. Methods: The inhibitory activities of the hydroalcoholic extracts of plants against oxidation of L-DOPA (as a substrate by mushroom tyrosinase were investigated. The amount of formed DOPAchrome was determined at 475 nm as optical density. Results: The extracts showed anti-tyrosinase activity weaker than positive control (Kojic acid. The inhibitory activity of tested plants: U.maritima, Z.majdae and P.divaricata against mushroom tyrosinase were 38.61, 29.70 and 25.74 % at 1.67 mg/mL, respectively. Conclusion: The most tyrosinase inhibitory activity was seen for U.maritima. However more investigations on human tyrosinase, toxicological and clinical studies are needed to confirm its activity.

  7. Inhibition of Tumor Growth and Immunomodulatory Effects of Flavonoids and Scutebarbatines of Scutellaria barbata D. Don in Lewis-Bearing C57BL/6 Mice

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    Tao Gong

    2015-01-01

    Full Text Available Immunomodulatory effect has been found to be an important therapeutic measure for immune responses against cancer. In this study, we evaluated the inhibition of Scutellaria barbata D. Don (SB, an anti-inflammatory and an antitumor Chinese herb, including flavonoids and scutebarbatines on tumor growth and its immunomodulatory effects in vivo. HPLC and LC/MS/MS methods were conducted for the analysis of flavonoids and scutebarbatines in SB. Lewis-bearing C57BL/6 mice model was established and tumor volume was evaluated by high frequency color ultrasound experiment. ELISA and western blot analysis were performed for the determination of immunomodulatory factors. SB treatment at the dose of 10, 6.67, and 3.33 g crude drug/kg/d significantly inhibited tumor growth of Lewis-bearing C57BL/6 mice with the inhibition rates of 44.41±5.44%, 33.56±4.85%, and 27.57±4.96%, respectively. More importantly, the spleen and thymus indexes were increased remarkably by SB treatment. SB could decrease IL-17, IL-10, FOXP3, TGF-β1, RORγt, and IL-6 levels whereas it could increase remarkably IL-2 and IFN-γ levels. Our results demonstrated that SB could inhibit tumor growth in vivo through regulating immune function in tumor-bearing mice and suggested that the immunomodulatory function of SB had a potential therapeutic effect in lung cancer.

  8. Contribution to the analysis of the essential oil of Helichrysum italicum (Roth) G. Don. Determination of ester bonded acids and phenols.

    Science.gov (United States)

    Mastelić, Josip; Politeo, Olivera; Jerković, Igor

    2008-04-07

    The essential oil of Helichrysum italicum (Roth) G. Don (everlasting or Immortelle essential oil) was isolated by hydrodistillation and analysed by GC and GCMS. Forty four compounds were identified. The main components were alpha-pinene(12.8%), 2-methyl-cyclohexyl pentanoate (11.1 %), neryl acetate (10.4%), 1,7-di-epi-alpha-cedrene (6.8%) and other compounds. The oil was fractionated and ester-containing fraction was hydrolysed with KOH/H(2)SO(4). The liberated volatiles were analysed by GC and GC-MS: three phenols and twenty seven volatile carboxylic acids were identified[70% low fatty acids (C(2)-C(5)), 15% C(10)-C(12) acids and 15% other acids]. The main acids were acetic acid (24.3%) propanoic acid (17.2%), 2-methylpropanoic acid (11.4%),dodecanoic acid (8.7%), 2-methylbutanoic acid (8.3%), (Z)-2-methylbutenoic acid(5.1%) and decanoic acid (4.6%). With respect to the identified bonded carboxylic acids,the minimal number of esters in the oil was twenty seven, but their overall quantity was probably larger due to different possible combinations of alcohols with acids to form esters. On the other hand, only six main esters were identified in the oil before fractionation and hydrolysis.

  9. Contribution to the Analysis of the Essential Oil of Helichrysum italicum (Roth G. Don. – Determination of Ester Bonded Acids and Phenols

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    Igor Jerković

    2008-04-01

    Full Text Available The essential oil of Helichrysum italicum (Roth G. Don (everlasting orImmortelle essential oil was isolated by hydrodistillation and analysed by GC and GCMS.Forty four compounds were identified. The main components were α-pinene(12.8%, 2-methyl-cyclohexyl pentanoate (11.1 %, neryl acetate (10.4%, 1,7-di-epi-α-cedrene (6.8% and other compounds. The oil was fractionated and ester-containingfraction was hydrolysed with KOH/H2SO4. The liberated volatiles were analysed by GCand GC-MS: three phenols and twenty seven volatile carboxylic acids were identified[70% low fatty acids (C2-C5, 15% C10-C12 acids and 15% other acids]. The main acidswere acetic acid (24.3% propanoic acid (17.2%, 2-methylpropanoic acid (11.4%,dodecanoic acid (8.7%, 2-methylbutanoic acid (8.3%, (Z-2-methylbutenoic acid(5.1% and decanoic acid (4.6%. With respect to the identified bonded carboxylic acids,the minimal number of esters in the oil was twenty seven, but their overall quantity wasprobably larger due to different possible combinations of alcohols with acids to formesters. On the other hand, only six main esters were identified in the oil beforefractionation and hydrolysis.

  10. Effets oestrogéniques du macéré aqueux des feuilles de Holarrhena floribunda (G. Don Dur & Schinz chez la rate ovariectomisée

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    Sawadogo l;

    2006-01-01

    Full Text Available Oestrogenic effects of macerated aqueous extracts of the leaves of Holarrhena fl oribunda (G. Don Dur & Schinz on ovariectomized rat. Estrogenic effects of aqueous extracts of leaves of Holarrhena fl oribunda have been evaluated by uterotrophic assay. Ovariectomized mice were used and treated subcutaneously during seven days with 50, 100, 200 mg.kg-1 doses of Holarrhena fl oribunda and with 100, 200 mg.kg-1 doses of Holarrhena fl oribunda plus 25 mg.kg-1 of oestradiol 17-β. Estrogenic activity was analysed by uterine dry and wet weight, surrenal gland wet weight, vaginal opening, protein and cholesterol level in uteri horn. Administration of extracts to the doses of 100 and 200 mg.kg-1 exhibits increase of uterine dry and wet weight, surrenal gland wet weight, vaginal opening, protein levels and decrease of level of cholesterol in uterine horn. The results suggest that, aqueous extracts of Holarrhena fl oribunda possesses estrogenic type effect. But when 100 and 200 mg.kg-1 of Holarrhena fl oribunda were given alone with 25 mg.kg-1 of estradiol 17-β, the estrogenic effect was slight. These results supposed that H. fl oribunda is a weak phytoestrogen and the aqueous extracts of the leaves behad as partial agonistic

  11. Efeito do volume de tubetes e tipo de substratos na qualidade de mudas de Cryptomeria japonica (L.F. D. Don.

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    Constâncio Bernardo dos Santos

    2009-10-01

    Full Text Available Normal 0 21 false false false MicrosoftInternetExplorer4 A Cryptomeria japonica (L.F. D. Don. é uma espécie de grande potencial para plantios nas regiões altas e frias do Brasil. Destaca-se pelo seu rápido crescimento, boa adaptação ao clima e solo do sul do País, e boa resposta às tecnologias silviculturais, associada à qualidade e diversidade de utilização de sua matéria-prima para fábricas de celulose e papel, chapas, construções de casas, móveis, barcos e navios, entre outras. Neste trabalho, buscou-se avaliar o desenvolvimento das mudas produzidas em diferentes tipos de tubetes e de substratos. Usou-se um experimento bifatorial no delineamento inteiramente casualizado com oito tratamentos em cinco repetições com quarenta mudas por tratamento. Os resultados indicaram que, para a produção de mudas desta espécie, o substrato de solo + vermiculita foi o que apresentou melhor crescimento das plantas, em recipiente de 120 cm3.

  12. The recent multi-ethnic global lung initiative 2012 (GLI2012) reference values don't reflect contemporary adult's North African spirometry.

    Science.gov (United States)

    Ben Saad, Helmi; El Attar, Mohamed Nour; Hadj Mabrouk, Khaoula; Ben Abdelaziz, Ahmed; Abdelghani, Ahmed; Bousarssar, Mohamed; Limam, Khélifa; Maatoug, Chiraz; Bouslah, Hmida; Charrada, Ameur; Rouatbi, Sonia

    2013-12-01

    The applicability of the recent multi-ethnic reference equations derived by the ERS Global Lung Initiative (ERS/GLI) in interpreting spirometry data in North African adult subjects has not been studied. To ascertain how well the recent ERS/GLI reference equations fit contemporary adult Tunisian spirometric data. Spirometric data were recorded from 1192 consecutive spirometry procedures in adults aged 18-60 years. Reference values and lower limits of normality (LLN) were calculated using the local and the ERS/GLI reference equations. Applied definitions: large airway obstructive ventilatory defect (LAOVD): FEV1/FVC contemporary Tunisian spirometry. Using Tunisian reference equations, 71.31%, 6.71% and 19.04% of spirometry records were interpreted as normal, and as having, LAOVD and TRVD, respectively. Using the ERS/GLI reference equations, these figures were respectively, 85.82%, 4.19% and 8.39%. The mean ± SD Z-scores for the contemporary healthy North African subject's data were -0.55 ± 0.87 for FEV1, -0.62 ± 0.86 for FVC and 0.10 ± 0.73 for FEV1/FVC. The present study don't recommend the use of the recent ERS/GLI reference equations to interpret spirometry in North African adult population. Copyright © 2013 Elsevier Ltd. All rights reserved.

  13. Review of Juan Coloma, «"Década de la pasión", "Cántico de la resurrección" de don Juan Coloma, conde de Elda y virrey de Cerdeña. Añádese en apéndice su poesía profana y el epistolario diplomátic con don Juan de Zúñiga», ed. Pedro M. Cátedra y Javier Burguillo, Salamanca, SEMYR, 2015, 532 pp. ISBN 978-84-941708-7-4

    Directory of Open Access Journals (Sweden)

    Martín Zulaica Lopez

    2017-05-01

    Full Text Available Review of Juan Coloma, «Década de la pasión», «Cántico de la resurrección» de don Juan Coloma, conde de Elda y virrey de Cerdeña. Añádese en apéndice su poesía profana y el epistolario diplomátic con don Juan de Zúñiga, ed. Pedro M. Cátedra y Javier Burguillo, Salamanca, SEMYR, 2015, 532 pp. ISBN 978-84-941708-7-4

  14. Caracterización de la Fábrica de Ladrillo del Palacio del Infante Don Luis, Boadilla del Monte, Madrid

    Directory of Open Access Journals (Sweden)

    Fort, R.

    2004-04-01

    Full Text Available Brickwork from the Palacio del Infante Don Luis Antonio de Borbón (Boadilla del Monte, Madrid, 18th century has been characterised, as well as the conservation degree of the materials has been determined. The original brick is of low quality and its mineralogical paragenesis shows firing temperatures of 750-850º C. Its high water absorption capacity and porosity are responsible for its characteristic alteration and disgregation. Restoration brick is of better quality, fired at higher temperatures (~900º C. In relation to the original mortar, it is a lime one, with a relation close to 1:2; aggregates are plurimineral and an average grain size of 1,50 mm. Mortars from following restorations are different from the original ones, not in composition, practically the same with the exception of the most modern mortar which is cementbased, but in their dosification and in the aggregates grain size, as well as in the finishing of the joint. Repointing of the original brickwork, together with the presence of water (dampness, and the low quality of brick due to an insuficient and heterogeneous firing, are resposible of the deterioration the brick undergoes.

    Se ha caracterizado la fábrica de ladrillo existente en el Palacio del Infante Don Luis Antonio de Borbón (Boadilla del Monte, Madrid, siglo XVIII, y se ha definido el estado de conservación de los materiales. El ladrillo original es de baja calidad y su paragénesis mineral indica una temperatura de cocción de 750-850ºC. Su elevada capacidad de absorción de agua y alta porosidad, son responsables de su alteración y disgregación. El ladrillo de restauración es de mejor calidad, cocido a mayor temperatura (~900ºC. En cuanto al mortero original, es un mortero de cal de relación cercana a 1:2; los áridos son pluriminerales y tamaño medio de 1,50 mm. Los morteros de las sucesivas restauraciones se diferencian del original, no en la composición, que es prácticamente la misma a

  15. 'I want a choice, but I don't want to decide'--a qualitative study of pregnant women's experiences regarding early ultrasound risk assessment for chromosomal anomalies.

    Science.gov (United States)

    Aune, Ingvild; Möller, Anders

    2012-02-01

    To increase our understanding of how pregnant women experience early ultrasound examination that includes a risk assessment for chromosomal anomalies and how such women perceive the test results. Qualitative study at St. Olavs Hospital in Norway. Both pre- and post-examination interviews were conducted with ten pregnant women who underwent risk assessment for chromosomal anomalies. Grounded theory was used to analyse the results. The study generated a core category (I want a choice, but I don't want to decide), which related to the conflict between choice and decision making. There were also five main categories (existential choices, search for knowledge, anxiety, feeling of guilt and counselling and care). The main categories describe the complex feelings experienced by the women regarding the risk assessment. Factors contributing to the difficulty of choice included loss of control and coping, emotional connection to the fetus and social pressure. As the women sought independent choices without any external influence, they also felt greater responsibility. The women's understanding of the actual risk varied, and they used different types of logic and methods to evaluate the risk and reach a decision. The pregnant women in this study wanted prenatal diagnostic information and easy access to specialty services. Stress-related feelings and non-transparent information about the actual and perceived risks as well as personal moral judgments made the decision-making process complicated. Improved distribution of information and frequent contact with health professionals may help such women to make informed choices in accordance with their values and beliefs. Copyright © 2010 Elsevier Ltd. All rights reserved.

  16. «Dar comida obligando a repartirla». Un modelo de don maya-ch'orti' en proceso de transformación

    Directory of Open Access Journals (Sweden)

    López García, Julián

    2001-12-01

    Full Text Available The author discusses the importance of food giving among the Ch'orti' of eastern Guatemala. For this Maya people, food giving is a way of facilitating community cohesion, a purpose than can be seen in the daily gifts of food and especially in important rituals such as the recubal In a recubal, a father gives food to his godfather following an offering model which the author calls «giving so as to cause to redistribute.» The amount of the food is so large, and its kind so special, that the receiver finds himself compelled to redistribute the offering among a large number of villagers. Nowadays, the importance that these gifts have for community integration is being undermined by two types of discourses coming from the Mestizo world: a discourse on poverty and another on superstition. These discourses portend other social effects for Ch'orti' communities.

    Se analiza la importancia de los regalos de comida para el mantenimiento de la cohesión comunitaria entre los mayas-ch'orti' del oriente de Guatemala. Eso se percibe en los regalos cotidianos de comida pero, sobre todo, en aquéllos que se producen como consecuencia de actos rituales trascendentes como el recubal (regalo de comida de padres a compadres. En el recubal, se regala tal cantidad de comida y de una cualidad tan particular que el receptor se ve obligado a repartir la ofrenda. Ese modelo de don lo he llamado «dar obligando a repartir». En la actualidad, el modelo comienza a resquebrajarse como consecuencia de la irrupción desde el mundo ladino de dos tipos de discurso que lo cuestionan, uno sobre la pobreza y otro sobre la superstición. Analizo finalmente las implicaciones sociales que sobre las comunidades ch'orti' puede tener el triunfo de ese tipo de discursos.

  17. Con le galoches, Basaglia e Don Milani, a spasso per la Via Lattea: cooperazione educativa, pedagogia del Cielo e politica dell’esperienza

    Directory of Open Access Journals (Sweden)

    Anna Barracco

    2017-08-01

    Full Text Available L'articolo riporta, a caldo, i pensieri, le riflessioni e le emozioni della psicoanalista e past president del Cipra, Anna Barracco, che scaturiscono dopo aver preso parte a un'esperienza di aggiornamento professionale sperimentale, rivolto agli insegnanti e promosso dal Movimento per la Cooperazione Educativa, svoltasi a Gubbio, dal 21 al 23 Aprile 2017. Il progetto è volutamente interdisciplinare e aperto a tutti, ma per lo più accoglie insegnanti della scuola dell'infanzia e della primaria. L'autrice mette in valore l'eredità spirituale e filosofica di Don Milani e della Scuola di Barbiana, eredità che appare molto viva nei gesti e negli stili che caratterizzano il seminario. Barracco ritrova, non senza un velo di malinconia, la forza e il respiro utopistico di un approccio che scavalca la dissimmetria fra discente e docente, dove tutti sono in qualche modo allievi - o ricercatori - del Cielo, cioè della materia che si vuole osservare, ma della quale siamo parte: il Cielo come sfondo integratore, in senso didattico, certamente, ma in senso anche esistenziale e filosofico. Un’esperienza di apprendimento e di comunità, che l'autrice mette in tensione con le esperienze basagliane e con la necessità di ritrovare un più fattivo dialogo fra le professioni umanistiche della cura e dell'educazione, indicando come strumento la messa in gioco del proprio desiderio di apprendere dall'esperienza, di guardare alle cose e alle persone, senza che lo schermo di tutto quello che crediamo di sapere ci impedisca di vedere.

  18. La dignidad y el sentido. Narrativa audiovisual y enfermedad mental en It´s such a beautiful day (Don Hertzfeldt, 2012

    Directory of Open Access Journals (Sweden)

    Aarón Rodríguez Serrano

    2015-11-01

    Full Text Available El presente trabajo pretende proponer un análisis de la cinta It´s such a beautiful day (Don Hertzfeldt, 2012, al trasluz de las relaciones que se establecen entre narrativa fílmica y enfermedad mental. Se trata de un objeto de estudio novedoso, ya que es el primero que se publica en castellano sobre dicha película, y además, propone algunas variaciones metodológicas sustanciales sobre la aproximación que desde el análisis fílmico se pueden realizar a propósito del tratamiento visual de la enfermedad. Para ello, se utilizarán las herramientas habituales del estudio narratológico del film, incorporando además aquellos préstamos de la filosofía del siglo XX especialmente relevantes por su relación con la experiencia de la realidad y sus quiebras. El artículo está estructurado mediante una introducción y una serie de clarificaciones metodológicas que posteriormente permiten analizar con cierta profundidad tres grandes apartados narrativos: en primer lugar, las relaciones que se establecen entre espacio y tiempo fílmico y enfermedad mental. En segundo lugar, la estructura tripartita y no lineal de la cinta, con sus correspondientes núcleos de significación narrativos. Por último, el complejo sistema enunciativo de la película, con el desglose de la problemática de su sistema de narradores.

  19. Mechanisms for dominance in an early successional old field by the invasive non-native Lespedeza cuneata (Dum. Cours.) G. Don

    Science.gov (United States)

    Brandon, A.L.; Gibson, D.J.; Middleton, B.A.

    2004-01-01

    Researchers studying invasive plants often concentrate their efforts on predictive models thought to allow invasive plants to dominate native landscapes. However, if an invasive is already well established then experimental research is necessary to provide the information necessary to effectively manage the species. Prescribing appropriate management strategies without prior experimental research may not only be ineffective but also may squander limited resources or have the unintended consequence of furthering spread. Lespedeza cuneata (Dum. Cours.) G. Don. is a well-established invasive plant of old fields and tall-grass prairie in the US. Managers suspect this species shades-out native plants and this is proposed as its primary mechanism for dominance. Using field experiments we tested probable factors allowing the speices to establish itself and once established, interfere in old field plant communities. We also examined the effects of two common anthropogenic disturbances (mowing and nutrients) on L. cuneata growth and establishment. When L. cuneata was treated (clipping, herbicide and stem pull-back) there was a significant increase in species richness and native speices cover. Stem density and canopy cover of L. cuneata increased significantly with mowing frequency but decreased with nutrient input. We suggest that mowing benefits L. cuneata while also hindering woody competition. Results also indicate L. cuneata is less prevalent on nutrient enriched soils than on unamended soil. Lespedeza cuneata appears to suppress native plants by shading them out and it can subsequently take over grassland communities. Since it has a varying response to human induced disturbances and may actually benefit from mowing, land managers should be cautious when utilizing this as a management tool.

  20. Sub-Compartment Variation in Tree Height, Stem Diameter and Stocking in a Pinus radiata D. Don Plantation Examined Using Airborne LiDAR Data

    Directory of Open Access Journals (Sweden)

    Hanieh Saremi

    2014-08-01

    Full Text Available Better information regarding the spatial variability of height, Diameter at Breast Height (DBH and stocking could improve inventory estimates at the operational Planning Unit since these parameters are used extensively in allometric equations, including stem volume, biomass and carbon calculations. In this study, the influence of stand stocking on height and DBH of two even aged radiata pine (Pinus radiata D. Don stands were investigated using airborne Light Detection and Ranging (LiDAR data at a study site in New South Wales, Australia. Both stands were characterized by irregular stocking due to patchy establishment and self-thinning in the absence of any silvicultural thinning events. For the purpose of this study, a total of 34 plots from a 34 year old site and 43 plots from a nine year old site were established, from which a total of 447 trees were sampled. Within these plots, DBH and height measurements were measured and their relationships with stocking were evaluated. LiDAR was used for height estimation as well as stem counts in fixed plots (stocking. The results showed a significant relationship between stem DBH and stocking. At both locations, trees with larger diameters were found on lower stocking sites. Height values were also significantly correlated with stocking, with taller trees associated with high stocking. These results were further verified of additional tree samples, with independent field surveys for DBH and LiDAR-derived metrics for height analysis. This study confirmed the relationship between P. radiata tree heights and stem diameter with stocking and demonstrated the capacity of LiDAR to capture sub-compartment variation in these tree-level attributes.

  1. Ecospirituality in the Age of Technological Overkill: Body-Time Reclamation in the Fiction of Alan Lightman and Don DeLillo

    Directory of Open Access Journals (Sweden)

    Jonathan Butler

    2011-01-01

    Full Text Available In exploring the link between ecospirituality and the hard sciences, I argue that theformer provides a much-needed complement to the latter. The fragmentation ofdisciplinary pursuits fostered by the Enlightenment and by the continued progress ofunquestioned technological advance as an end in itself finds its ultimate expression inour current disconnection from the natural world, from each other, and even fromourselves. As a corrective to such disconnection, ecospiritual impulses emerge in anattempt to unify a discombobulated subject, a self so fragmented by the multiplenarratival requirements of a communication-obsessed age (where we can be reached bycell phone, regular phone, multiple email addresses, Facebook, and other social mediathat the "contemplative" facet of being human within the rhythms of the natural worldis all but obscured-indeed, is hardly given the requisite environment in which tofunction. Against this over-reliance on technology, on where the hard sciences have ledus, ecospirituality emerges as a balm for the terrorized human spirit. Don DeLillo'srecent novel Point Omega documents this poignantly. His narrator speaks of the "usualterror" of cities with their "endless counting down," with people constantly checkingtheir watches and other time-keeping devices. DeLillo's protagonist moves to the desertwhere "geological time" becomes the paradigm through which a restorative calm isgenerated. Alan Lightman's fiction proves even more relentless in its depiction of thedissociation engendered by an over-reliance on technology. Lightman's protagonist inThe Diagnosis is an information trader who suffers a breakdown and is only restored towell-being through a re-acquaintance with his own natural body rhythms along withthose of the natural world. Many of the characters in the short-story collectionEinstein's Dreams also find that a connection to nature counteracts the senselesscompetition of a consumer-driven, technologically

  2. Korean immigrants don't buy health insurance: The influences of culture on self-employed Korean immigrants focusing on structure and functions of social networks.

    Science.gov (United States)

    Oh, Hyunsung; Jeong, Chung Hyeon

    2017-10-01

    Culture has been pinpointed as a culprit of disparities in health insurance coverage between Korean immigrants and other ethnic groups. This study explored specific mechanisms by which culture influences a decision to buy health insurance among self-employed Korean immigrants living in ethnic enclaves by focusing on the structure and functions of social networks. Between March and June 2015, we recruited 24 Korean immigrant adults (aged 18 or older) who identified as self-employed and being uninsured for substantial periods before 2014 in Southern California. Interviews were conducted in Korean, and Korean transcripts were translated into English by two bilingual interpreters. Using constant comparative analysis, we explored why participants didn't purchase health insurance after migrating to the United States and how their social networks influenced their decisions whether to purchase health insurance. Results indicate Korean immigrants sought health information from dense and homogeneous social networks whose members are mostly Korean immigrants embedded in similar social contexts. Social learning was frequently observed when people sought health care while uninsured. However, respondents often noted social ties do not provide helpful information about benefits, costs, and ways to use health insurance. "Koreans don't buy health insurance" was a dominant social norm reported by most respondents. Findings indicate that social learning and normative influence occur inside social networks and these mechanisms seemingly prevent purchasing of health insurance. In addition to the individual mandate in the Patient Protection and Affordable Care Act, more targeted approaches that consider the structure and functions of social networks could improve the public health of Korean immigrants. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. Comparative study on the composition of free amino acids and derivatives in the two botanical origins of an edible Chinese herb "Xiebai", i.e., Allium chinense G. Don and Allium macrostemon Bunge species.

    Science.gov (United States)

    He, Quan; Huang, Shaohui; Wu, Yuehong; Zhang, Wenqi; Wang, Fanchao; Cao, Jiawei; Sheng, Qing; Liang, Zongsuo; Liu, Lili; Ou, Wen-Bin

    2018-04-01

    Xiebai is an edible Chinese herb with various health and therapeutic benefits. To evaluate its nutritional and health values, the free amino acids and derivatives of its two botanical origins (i.e., Allium chinense G. Don and Allium macrostemon Bunge) were isolated using a solvent extraction method and analyzed using automatic amino acid analysis and ultra-performance liquid chromatography-quadrupole-time of flight (UPLC-Q-TOF) mass spectrometry. Our data show that both plants contain abundant free amino acids, and the amount of total free amino acids in A. chinense G. Don is higher than that in A. macrostemon Bunge. The free amino acid compositions in the two plants are qualitatively similar, including nineteen proteinogenic and four non-proteinogenic amino acids. The identified proteinogenic amino acids include eight essential amino acids and five semi-essential amino acids. The sum of essential and semi-essential amino acids accounts for 64.9% and 69.7% of the total free amino acids of the two plants, respectively. The principal amino acids of both plants, from highest concentration to lowest concentration, are arginine, glutamine, glutamic acid, asparagine and serine. A. chinense G. Don is also rich in citrulline and lysine. In addition, two amino acid derivatives were identified from the two plants, i.e., the proline analog N‑methyl‑proline and the dipeptide H-Glu-Tyr-OH. For the first time, the presence of N‑methyl‑proline in the plants of the Allium genus and the presence of H-Glu-Tyr-OH in unprocessed food sources are reported. The influences of the identified substances on the flavor, nutrition and health values of Xiebai are discussed. Copyright © 2018 Elsevier Ltd. All rights reserved.

  4. Sátira, caricatura y parodia en la Argentina de fines del siglo XIX. Un caso paradigmático: el periódico "Don Quijote" (1884-1903, de Buenos Aires

    Directory of Open Access Journals (Sweden)

    Lic. María Ximena Avila

    2000-01-01

    Full Text Available estudio se fundamenta en una investigación histórico-periodística que da cuenta de las condiciones socio-culturales, las luchas políticas, la participación de los sujetos sociales en la historia argentina de 1890. El periódico Don Quijote es un órgano partidario opositor al gobierno nacional, de un grupo político "el radicalismo" que, a partir de 1890, surge como voz disidente que intentaba proponerse como una alternativa a la hegemonía de los partidos conservadores.

  5. Cómo Don Quijote viajó a las Américas. Metamorfosis del héroe nacional de España en textos de Rubén Darío, Carlos Fuentes y Kathy Acker

    OpenAIRE

    Sturm-trigonakis, Elke

    2011-01-01

    Only a few fictional heroes symbolize a supposed national character in the way Cervantes’ Don Quijote does in the case of Spain. His adaptation to the ethnic, historical and cultural contexts of the Americas is discussed in this paper, focusing especially on the mechanisms of transtextualization in the short story D. Q. by Rubén Darío (1899), in Terra Nostra by Carlos Fuentes (1975), and in Kathy Acker’s «post-feminist» novel Don Quixote which was a dream from 1986. These three texts demonstr...

  6. Enhanced anticancer effects of Scutellaria barbata D. Don in combination with traditional Chinese medicine components on non-small cell lung cancer cells.

    Science.gov (United States)

    Wang, Qian; Acharya, Narayan; Liu, Zhongwei; Zhou, Xianmei; Cromie, Meghan; Zhu, Jia; Gao, Weimin

    2018-05-10

    Experience-based herbal medicine as a complementary to modern western medicine has triggered an array of studies in quest of novel anticancer drugs. Scutellaria barbata D. Don (SB) is commonly used to treat different types of cancers, but its molecular mechanism of action is not clearly understood. In this study, we attempted to elucidate the mode of action of a traditional Chinese medicine prescription with a total of 14 components, named Lian-Jia-San-Jie-Fang (LJSJF, in Chinese), where SB works as the "principle" against non-small cell lung cancer (NSCLC) cells. Four different NSCLC cell lines (A549, H460, H1650, and H1975) were used. Cytotoxicity, in vitro tumorigenicity, gene expression, and protein expression were analyzed by MTT assay, soft agar assay, real-time PCR, and Western blots, respectively. Among the 14 components in LJSJF, SB was the only one to possess cytotoxic effects at its pharmacologically relevant doses. Additionally, we observed synergistically dose-dependent cytotoxic effects of SB in combination with other LJSJF components. After SB or LJSJF treatment, significant reductions in colony number and/or size were observed in A549 and H460; a notable dose-dependent decrease in EGFR was observed in A549, H460, and H1650; significant downregulation in EGFR and its downstream signaling targets mTOR and p38MAPK were also observed in A549 and H460; and p53 and p21 were significantly increased while survivin, cyclin D1, and MDM2 were significantly decreased in A549. Additionally, p53, p21, and Mettl7b were decreased, but p73 was increased in H460. Neither EGFR nor p53 was changed in H1975. Therefore, SB or LJSJF may induce cytotoxic effects by regulating multiple and/or distinct apoptotic pathways in different NSCLC cells. LJSJF exerts more pronounced cytotoxic effects against NSCLC cells than SB does by synergistically regulating the underlining molecular mechanisms including EGFR and/or p53 signaling pathways. Copyright © 2018 Elsevier B.V. All

  7. Telling the truth: Don DeLillo in an age of amnesia and redressDOI:10.5007/2175-8026.2010n59p176

    Directory of Open Access Journals (Sweden)

    Marni Gauthier

    2010-03-01

    Full Text Available The December 2006 Iran Holocaust denial Conference and the international excoriation of it reveal a paradox of two cultural strands that are emblematic of the legacy of the twentieth century: official denial and historical amnesia on the one hand; and (international attempts at truth telling and historical redress on the other. Massive violence–and associative denial—punctuate the entire twentieth century. Yet coordinated tenacious efforts at public acknowledgment of “what really happened”–a recurrent and insistent emphasis in this context of trials, reparations, and above all, truth commissions—and concomitant historical redress for state-sanctioned crimes is a particularly recent phenomenon, unique, in fact, to the 1990s. But it is not only political readers who address what Priscilla B. Hayner, in her exhaustive study of truth commissions calls, “unspeakable truths.” This essay addresses the incongruity between the recent global concern with truth telling, official apology, memory and historical redress on the one hand–an obsession that certainly includes the US—and American amnesia on the other. It is in the interstices of these two apposite late twentieth century phenomena–amnesia and truth telling; “history” distinct from “the truth of the past”; “official” opposed to “vernacular” memory — that, I argue, a new genre of historical novel develops and performs a vital cultural work: telling the truth in an age of amnesia and redress. Such novels engage the recalcitrant materials of historical experience to assert truth claims that in turn challenge nationalist histories and revise traditional mythologies. Among the foremost authors of this new “truth-telling” historical novel is Don DeLillo. Americana, the vital precursor to Libra and especially to Underworld, is the definitive harbinger of DeLillo’s third century of work that writes both within and against postmodernism. In these Cold-War era

  8. Next generation sequencing and de novo transcriptome analysis of Costus pictus D. Don, a non-model plant with potent anti-diabetic properties

    Directory of Open Access Journals (Sweden)

    Annadurai Ramasamy S

    2012-11-01

    Full Text Available Abstract Background Phyto-remedies for diabetic control are popular among patients with Type II Diabetes mellitus (DM, in addition to other diabetic control measures. A number of plant species are known to possess diabetic control properties. Costus pictus D. Don is popularly known as “Insulin Plant” in Southern India whose leaves have been reported to increase insulin pools in blood plasma. Next Generation Sequencing is employed as a powerful tool for identifying molecular signatures in the transcriptome related to physiological functions of plant tissues. We sequenced the leaf transcriptome of C. pictus using Illumina reversible dye terminator sequencing technology and used combination of bioinformatics tools for identifying transcripts related to anti-diabetic properties of C. pictus. Results A total of 55,006 transcripts were identified, of which 69.15% transcripts could be annotated. We identified transcripts related to pathways of bixin biosynthesis and geraniol and geranial biosynthesis as major transcripts from the class of isoprenoid secondary metabolites and validated the presence of putative norbixin methyltransferase, a precursor of Bixin. The transcripts encoding these terpenoids are known to be Peroxisome Proliferator-Activated Receptor (PPAR agonists and anti-glycation agents. Sequential extraction and High Performance Liquid Chromatography (HPLC confirmed the presence of bixin in C. pictus methanolic extracts. Another significant transcript identified in relation to anti-diabetic, anti-obesity and immuno-modulation is of Abscisic Acid biosynthetic pathway. We also report many other transcripts for the biosynthesis of antitumor, anti-oxidant and antimicrobial metabolites of C. pictus leaves. Conclusion Solid molecular signatures (transcripts related to bixin, abscisic acid, and geranial and geraniol biosynthesis for the anti-diabetic properties of C. pictus leaves and vital clues related to the other phytochemical functions

  9. Don't Get, Don't Spread: Seasonal Flu

    Centers for Disease Control (CDC) Podcasts

    2010-09-29

    In this podcast, Dr. Joe Bresee describes how to keep from getting the seasonal flu and spreading it to others.  Created: 9/29/2010 by National Center for Immunization and Respiratory Diseases (NCIRD).   Date Released: 9/29/2010.

  10. Postphenomenology - "Festschrift" for Don Ihde

    DEFF Research Database (Denmark)

    Riis, Søren

    2008-01-01

    What do underwater animals, artificial limbs, and a wrecked space shuttle have in common?  Where do the humanities and the natural sciences intersect?  Is technology a Leviathan in our midst, an aid that stabilizes and protects our fragile biology, or an instrument that propels us ever closer...... it captures the spirit of Ihde's oeuvre and conveys the appreciation experienced by a number of prominent scholars.  Ultimately, the book successfully bends, breaks, and extends the multi-stable lines of thought that appear throughout Ihde's versatile work.  Through provocative case studies and critical...

  11. The vindication of Don Quijote

    DEFF Research Database (Denmark)

    Jensen, Cathrine Ulla; Panduro, Toke Emil; Lundhede, Thomas

    In this article we quantify the marginal external effects of nearby land based wind turbines on property prices capitalized through traded residential properties located within 2,500 meters or less. We succeed in separating the effect of noise and visual pollution from wind turbines. This was ach...

  12. Don't tempt me!

    CERN Multimedia

    Stefan Lueders, Computer Security Team

    2013-01-01

    Over your CERN career, have you ever changed activities, functions or responsibilities, but nevertheless kept the access to your “old” control systems or computing services? Accessing the systems for which you are no longer responsible seems innocent enough, because you just want to help by using your previous work and experience but… Does this sound familiar to you? Let’s think this one through because it may have bad consequences.   In my previous life, I worked as a software developer and system expert for the “Detector Safety System”, a control system used in the LHC experiments. After this system had been deployed and the project moved into maintenance mode, I was assigned new responsibilities which finally led me to the CERN Computer Security Team. My system was now in the care of a new team of excellent people. However, as my experience of the Detector Safety System didn't just disappear, I was kept on their expert l...

  13. Don't demotivate, discriminate

    NARCIS (Netherlands)

    J.J.A. Kamphorst (Jurjen); O.H. Swank (Otto)

    2013-01-01

    markdownabstract__Abstract__ This paper offers a new theory of discrimination in the workplace. We consider a manager who has to assign two tasks to two employees. The manager has superior information about the employees' abilities. We show that besides an equilibrium where the manager does not

  14. Pregnant? Don't Smoke!

    Science.gov (United States)

    ... Injury, Violence & Safety Life Stages & Populations Travelers’ Health Workplace Safety & Health Features Media Sign up for Features Get ... Smoking during pregnancy can cause babies to be born too small ...

  15. Don't Move Firewood

    Science.gov (United States)

    Northeastern Area, S& PF USDA Forest Service

    2006-01-01

    Our forests are threatened by nonnative insects that can kill large numbers of trees. Three recently introduced insects, emerald ash borer, Asian longhorned beetle, and Sirex woodwasp are wood-infesting species that can be transported long distances in firewood. Once transported into new areas, these insects can become established and kill local trees. We must STOP THE...

  16. Don't be scared.

    Science.gov (United States)

    Killick, S

    1996-01-01

    In the UK, recent changes to prescribing oral contraceptives (OCs) have contributed to acute difficulties in providing clinical services, interruptions or discontinuations of audit and research projects of the Royal College of Obstetricians and Gynaecologists' Faculty of Family Planning and Reproductive Health Care, and criticisms of the way its audit unit has handled nationally important information. Professional auditors should consider the problems caused by the sudden change in a long accepted gold standard as an opportunity. The unit has already received audits of the effect of changes concerning the risk of thromboembolism from gestodene and desogestrel containing OCs. Family planning providers need to consider whether their cascade system of information dissemination did not inform them quickly and completely of a necessary change in practice or whether it followed the information system available to clients (i.e., the national press) so that family planning providers are not prepared for consumer reports both qualitatively and quantitatively. Some potentially long-term difficulties have occurred, which probably could not have been avoided regardless. Some clinics had to dispense only a two-months supply of second generation OCs at a time. Problems linked to a large increase in clinic attendances (potentially longer waiting times, counseling time, poorer attendance rates, and possibly more OC discontinuations) will recur at two months and at regular intervals thereafter until new stocks are available to allow staggered follow-up appointments. Thus, the audit unit can refer to its on-going audits for these figures. The most difficult step of the audit cycle is to initiate a change in practice. The audit unit must first acquire data to handle appropriately OC scares from articles in the national press.

  17. Don´t Smoke!

    OpenAIRE

    Naudín Escuder, Andrés

    2016-01-01

    He creado 6 piezas de publicidad gráfica anti-tabaco que van desde 1947 hasta 1966. La originalidad reside en aprovechar estos contextos donde este tipo de publicidad prácticamente no existía y crear algo que sea coherente con la época donde se enmarca. Grado en Publicidad y Relaciones Públicas

  18. Ameerika Don Quijote / Kadri Kõusaar

    Index Scriptorium Estoniae

    Kõusaar, Kadri

    2008-01-01

    Leedu-juudi juurtega Sundance'i filmifestivali võitja Debra Granik, kelle esikfilm "Viimase piirini" ("Down to the Bone") pälvis 2004. aasta Sundance'i filmifestivalil nii parima režii kui ka parima naispeaosatäitja preemia (Vera Farmiga)

  19. Teoría y práctica del teatro: Títeres de Cachiporra. Tragicomedia de don Cristóbal y la señá Rosita

    OpenAIRE

    Arriazu Inúñez, Ainoa

    2014-01-01

    Este TFG consiste en un análisis de la obra “Títeres de Cachiporra. Tragicomedia de don Cristóbal y la señá Rosita”, a la vez que una representación del marco genérico de la farsa. Posteriormente se analizan los aspectos de la obra: personajes, caracterización, prólogo, espacio teatral, la boda y el entierro como aspecto importante dentro de la obra, recursos y lenguaje, el público y la crítica hacia la obra. Y por último, una unidad didáctica llevada a cabo en el colegio público San Babil...

  20. Scientific study of 13C/12C carbon and 18O/16O oxygen stable isotopes biological fractionation in grapes in the Black Sea, Don Basin and the Western Caspian regions

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    Kolesnov Alexander

    2017-01-01

    Full Text Available The report presents the results of a study of carbon and oxygen stable isotopes in carbohydrates and intracellular water of red and white grapes of 2016 wine-growing season in the Crimean peninsula areas, South-west coast of the Greater Caucasus, the Don basin and the Western Caspian region. The mass concentration of reducing sugars in the studied grape samples has been from 17.5 to 25.0 g/100 ml, titrated acids concentration (based on tartaric acid – from 6.0 to 9.1 g/l, the buffer capacity 34.1–63.2 mg-Eq/l. Red and white wine made from respective grapes contained from 0.5 to 3.6 g/l of residual sugar; from 11.1 to 14.5% ethanol by volume; buffer capacity was 35.2–52.6 mg-Eq/l. It has been found that the δ13CVPDB values for carbohydrates of red and white grape varieties as a result of biological fractionation of carbon isotopes in the agro-climatic conditions of plant growth for the studied geographical areas are ranging from − 26.74 to − 20.74‰ (the Crimean peninsula; from − 27.31 to − 21.58‰ (South West Coast of the Greater Caucasus, from − 27.33 to − 24.73‰ (Don Basin and from − 26.64 to − 23.17‰ (West Caspian. The δ13CVPDB values for ethanol of the red and white dry wines range from − 28.52 to − 24.26‰ (the Crimean peninsula; from − 29.23 to − 24.52‰ (South West Coast of the Greater Caucasus; from − 28.97 to − 26.22‰ (Don Basin; from − 29.14 to − 25.22‰ (Western Caspian. Compared with the surface water and groundwater (averages from δ18OVSMOW− 13.90 to − 6.38‰ and with precipitation (averages from δ18OVSMOW − 10.30 to − 9.04‰ the δ18OVSMOW values in intracellular water of grapes are the following: for the Crimean peninsula grapes, from 0.40 to 4.97‰; the South West Coast of the Greater Caucasus, from -2.11 to 6.29‰; the Don Basin, from − 2.21 to 6.26‰; the Western Caspian, from − 0.24 to 1.44‰. It has been noted that in conditions of

  1. The dark side of the Emancipation Reform of 1861 on the Don region: the history of the resettlement of one of the peasant community according the material of atamanskaya kontselyariya

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    Artyom Y. Peretyatko

    2016-03-01

    Full Text Available The article is devoted to the negative effects of the Emancipation Reform of 1861 on the Don region. The author shows that the result of this reform was mass resettlement of peasants in Mius District without the right of choice of land and compensation for real estate. The main attention is paid to the passive resistance of the inhabitants of one village attempts to evict them on unprepared areas, selected by their former landlord. Results of the research are the findings that the interests of the peasants living on the land of the yurt were completely ignored during the conduct of the Emancipation Reform, and that until 1868 the local officials refused to go on any compromise. Only after the complete failure of the brutal policies local administration made concessions and allowed peasants to select sites for relocation.

  2. Gracias cortesanas en El médico de su honra: más sobre la apuesta del bufón Coquín y el rey don Pedro

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    Adrián J. Sáez

    2014-06-01

    Full Text Available Muchos de los acercamientos a El médico de su honra de Calderón se han centrado en el examen de la función del gracioso Coquín en la dominante atmósfera seria y especialmente en la apuesta de los dientes con el rey don Pedro, que ha dado lugar a ciertas lecturas eróticas que conviene revisar. Tanto este chiste como el alcance y sentido general de la comicidad en el drama solo cobran sentido a la luz de la tradición bufonesca y cortesana, que se basa en un concepto del humor torpe y violento, enmarcado a la vez en la perfecta imbricación de la risa en las tragedias de Calderón.

  3. Reproducción del Cucarachero Común (Troglodytes aëdon, Aves, Troglodytidae en el Valle del Cauca Reproducción del Cucarachero Común (Troglodytes aëdon, Aves, Troglodytidae en el Valle del Cauca

    Directory of Open Access Journals (Sweden)

    Alvarez López Humberto

    1984-09-01

    .8 fledgelings per brood, a 90.2% nesting success. Breeding activity was recorded in every month of the year except March. Peaks of breeding in april and november-december coincided with rainfall peaks.EI presente trabajo describe la reproducción de Troglodytes aëdon (Aves:Troglodytidae en el Valle del Cauca (3°32' 20" N y 76° 31' 57" W, 976 m, Colombia, con base en observaciones de 24 nidos y de 44 individuos (11 adultos, 33 juveniles anillados para su reconocimiento individual. Los machos mantuvieron territorios permanentes de propósito múltiple cuyo tamafio promedio fluctuó entre 0.12 y 0.28 Ha. EI vínculo sexual monogámico se conservó a 10 largo de varias nidadas sucesivas y todos los cambios en la composición de las parejas siguieron a la desaparición de uno de los miembros.T. aëdon anida generalmente en cavidades y la mayoría de los nidos del presente estudio fueron construidos en nidales artificiales. Macho y hembra participaron en el proceso de la construcción, siendo notablemente mayor elaporte de la hembra en la etapa final. La construcción del nido ocupó entre 8 y 37 días, Los huevos fueron puestos a intervalos de aproximadamente 24hr en las primeras horas de la manana. Sus dimensiones y peso, en promedio, fueron respectivamente 18.5 x 13.8 mm y 1.8 g. EI tamaño de la nidada fluctuó entre 2 y 4 huevos, con un promedio de 3.2. El máximo número de nidadas para una hembra fue de 7 (20 huevos en un período de 17 meses y con un intervalo mínimo de 48 días entre posturas. Unicamente las hembras incubaron y dedicaron a este proceso entre 65 y 88% de su tiempo diurno. El promedio de duración para el período de incubación fue de 15 días y concluyó con eclosiones tanto seriadas como simultáneas, Durante los primeros siete días la hembra dedico el 37% de su tiempo diurno a cubrir los polluelos.Ambos padres alimentaron a los polluelos, siendo significativamente mayor el aporte de la hernbra. El promedio horario de visitas fue de 2.8 por polluelo

  4. Two «new» paintings inspired by Don Quixote and belonging to American art collections: Dance Scene (ca. 1656-1658?, anonymous although attributed to Joos van Crasbeeck (Neerlinter, Flanders 1605/1606-Brussels ca. 1660, and Dorothea (1823, by John Quidor (Tappan, New York State 1801-Jersey City, New Yersey 1881

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    Kenneth Brown

    2009-12-01

    Full Text Available This study presents a detailed analysis of two hitherto ignored or poorly understood paintings inspired by Cervantes’ Don Quijote de la Mancha: Dorothea (1823, by the New Yorker John Quidor, and Dance Scene (1656-1658, attributed to the Flemish Baroque master Joos van Craesbeeck. Dorothea is housed in the Brooklyn Museum of Art, and Dance Scene in Philadelphia’s The Rosenbach Museum and Gallery. The novelty of these two works is that Quidor’s is an ingenious and colourful improvement of a widely circulating black and white print, and van Craesbeeck’s miniature captures not only multiple don Quijotes and Sancho Panzas at a masquerade ball, but also the Dukes of Alba, for at the time the Duke was Governor General of the Spanish Netherlands.

  5. Être tenu par son erreur : les conséquences du fait de se tromper Remaining Caught up in Error: The Consequences of Being Wrong. An Example Based on Schütz’s Don Quixote

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    Nicolas Marquis

    2011-09-01

    Full Text Available Peut-on sortir indemne de ses erreurs ? En empruntant une voie dessinée par les recherches récentes relatives au fait de se tromper qui se démarquent d’une appréhension purement cognitiviste, cet article vise à explorer ce que fait l’erreur à la personne qui la commet. L’hypothèse qui est développée à la suite de Wittgenstein est que chaque acte, chaque contenu cognitif qui se verra qualifié d’erreur “tient” la personne, et risque de porter à conséquence sur la manière dont l’auteur de l’erreur pourra s’engager dans le monde. Il est ainsi possible de proposer une classification des erreurs en fonction du réarrangement qu’elles impliquent dans le système de ce que la personne sait, croit, vit. Afin d’approfondir cette hypothèse, l’article s’appuie sur le fameux texte d’A. Schutz intitulé Don Quichotte et le problème de la réalité. Le phénoménologue y analyse la manière dont le héros fantasque de Cervantès, figure extrême de ce que nous sommes au quotidien, s’arrange un temps pour continuer à vivre dans son sous-univers de chevalerie grâce à un environnement bienveillant, mais aussi comment le chevalier auto-proclamé sera inéluctablement amené à qualifier d’erreur l’ensemble de ce qu’il sait, croit ou vit lorsque le monde qui l’entoure se fera confrontant.Can we emerge unscathed from our errors ? In taking a path sketched out in recent research on the fact of being wrong that distances itself from a purely cognitivist understanding, this article seeks to explore what an error does to the person who makes it. The hypothesis that is developed, following Wittgenstein, is that every act, every cognitive content that ends up being described as error has “a hold” on the person and risks having consequences on the way the error’s author will be able to involve him/herself in the world. Hence it is possible to propose a classification of errors according to the rearrangement

  6. Claudia Demattè and Alberto del Río, Parodia de la materia caballeresca y teatro áureo. Edición de Las aventuras de Grecia y su modelo serio, el «Don Florisel de Niquea» de Montalbán

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    Javier Guijarro Ceballos

    2015-01-01

    Full Text Available Review of Claudia Demattè and Alberto del Río, Parodia de la materia caballeresca y teatro áureo. Edición de Las aventuras de Grecia y su modelo serio, el «Don Florisel de Niquea» de Montalbán, Servicio de Publicaciones de la Universidad de Navarra (Publicaciones digitales del GRISO, Pamplona, 2012, 247 pp. ISBN: 9788480813365.

  7. Una pasión por la antigüedad: la colección arqueológica de don Florentino Gimeno en Campeche durante el siglo XIX A passion for antiquity: Don Florentino Gimeno's 19th Century archaeological collection in Campeche

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    Lynneth S. Lowe

    2010-01-01

    Full Text Available Durante la segunda mitad del siglo XIX, don Florentino Gimeno, un comerciante español establecido en Campeche, logró conformar una impresionante colección de más de 12 000 piezas arqueológicas, la cual reflejaba una profunda pasión por el pasado prehispánico y sus evidencias materiales. El análisis de sus catálogos proporciona información invaluable acerca de la procedencia y características de muchas de las piezas -que procedían fundamentalmente de sitios de la región-, y nos permite apreciar también sus afanes por desarrollar una clasificación tipológica y funcional de acuerdo con los criterios intelectuales en boga. Asimismo, los datos registrados en diversos documentos y crónicas indican que su tienda-museo se convirtió en punto de referencia para viajeros y exploradores que visitaron Campeche durante aquellos años, como Brasseur de Bourbourg o Carl Hermann Berendt, entre otros. Su interés en reunir no solamente objetos arqueológicos, sino también documentos históricos, fue también muy apreciado por notables personajes locales, como los gobernadores Pablo García y Joaquín Baranda. En este artículo exploramos las distintas facetas de este incansable coleccionista, e intentamos arrojar luz sobre sus atinadas -y sorprendentemente objetivas- interpretaciones de la cultura material antigua. Finalmente, intentamos rastrear el paradero actual de su acervo.During the second half of the nineteenth century, Florentino Gimeno, a Spanish shopkeeper residing in the city of Campeche, amassed an impressive collection of over 12,000 archaeological artifacts, reflecting his profound passion for the pre-Hispanic past and its material evidence. His handwritten catalogs provide invaluable information regarding the provenience and characteristics of many of the objects that were found in the region, and the extensive lists also show how he developed a typological and functional classification for his collection that corresponded to the

  8. Séroprévalence des marqueurs viraux sur les dons du sang au Centre de Transfusion Sanguine, Hôpital Militaire d’Instruction Mohammed V de Rabat

    Science.gov (United States)

    Uwingabiye, Jean; Zahid, Hafidi; Unyendje, Loubet; Hadef, Rachid

    2016-01-01

    Le but de ce travail était de déterminer la prévalence du virus de l’immunodéficience humaine (VIH), du virus de l’hépatite B (VHB) et C (VHC) sur les dons du sang collectés au Centre de transfusion sanguine(CTS) de l’hôpital militaire d’instruction Mohammed V entre 2010 et 2012. Etude rétrospective menée auprès des donneurs de sang militaires âgés de 18 à 50 ans avec prédominance masculine (95%). L’entretien médical pré-don constitue la première barrière de sélection des sujets à risque. Le dépistage biologique était réalisé par technique immuno-enzymatique en milieu liquide utilisant des anticorps et/ou des antigènes. L’ELISA (enzyme linked immuno-sorbent assay) combiné de quatrième génération pour VHC et VIH a été utilisé. La confirmation a été faite en réalisant la même technique en double au CTS et au laboratoire de virologie. Dans notre série de 25661 échantillons testés, la prévalence du VHB était 3,97‰ (n=102), celle de VHC était 2,45 ‰ (n=63), celle de VIH était 0,15 ‰ (n=4). Un seul cas de coïnfection (0,039 ‰) par le VHB et VHC a été noté, aucune association entre VIH-VHB, VIH-VHC ou VHB, VHC et VIH n’a été enregistrée. Les taux faibles de séroprévalence des marqueurs viraux de notre étude montrent l’amélioration des mesures préventives en ce qui concerne la sélection des donneurs et des tests de dépistage. Cette prévalence constatée incite à maintenir l’utilisation du réactif combiné qui est la seule alternative à la biologie moléculaire pour les pays en voie de développement. PMID:28292147

  9. Les proverbes dans “El ingenioso hidalgo” don Quijote de La Mancha : des stéréotypes linguistiques et culturels révélateurs de la complexité du message cervantin

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    Sonia Fournet-Perot

    2009-12-01

    Full Text Available Le « langage stéréotypique » représente généralement l’ensemble des structures de la langue mettant en avant le savoir partagé et la connaissance du monde d’une société linguistique. Or, les proverbes ont de tous temps constitué la sagesse des nations ou sagesse populaire. La matière proverbiale représente donc, pour reprendre les mots de Henri Meschonnic, « une tentative empirique de mettre le monde en ordre ». Nous rejoignons ici la fonction fondamentale du stéréotype grâce à laquelle chaque individu a la possibilité de régler ses actions. Notre objectif est de tenter de démontrer que les proverbes, en tant que stéréotypes – à la fois linguistiques et culturels –, ne sont pas de simples ornements mais ont pour fonction de servir, en discours, la stratégie énonciative de l’œuvre littéraire au sein de laquelle ils sont incorporés. Nous avons choisi comme terrain d’analyse le Don Quijote de la Mancha de Miguel de Cervantès.El “lenguaje estereotípico” suele representar el conjunto de las estructuras de la lengua que ponen de realce el saber compartido y el conocimiento del mundo de una sociedad linguística. Ahora bien, los refranes siempre constituyeron la sabiduría de las naciones o sabiduría popular. Dichos enunciados representan, pues, según Henri Meschonnic, “une tentative empirique de mettre le monde en ordre”. Coincidimos en este punto con la función básica del estereotipo mediante la cual cada individuo puede ajustar sus acciones. Nuestra meta es intentar demostrar que los refranes, como esteretipos – linguísticos y culturales a la vez –, no son meros adornos sino que tienen como función servir, en discurso, la estrategia enunciativa de la obra literaria a la cual se incorporan. Hemos elegido como corpus el Don Quijote de la Mancha de Miguel de Cervantes.

  10. Comparative analysis of seed rain of Gaiadendron punctatum (Ruiz and Pavon) G. Don (loranthaceae) and Ternstroemia meridionalis mutis ex l.f. (theaceae) at natural municipal park Rancheria (Boyaca), Colombia

    International Nuclear Information System (INIS)

    Parada Quintero, Martha

    2012-01-01

    Gaiadendron punctatum (Ruiz and Pavon) G. Don and Ternstroemia meridionalis mutis ex l.f. are ornithochorous species of the high Andean forest; the first is abundant at natural municipal park Rancheria and the second rare at local level. The seed rain and fruiting phenology of G. punctatum and T. meridionalis were evaluated. Records were kept between March and December of 2010. This period included dry and wet seasons. Eight traps with a recollection surface of 1 m 2 were installed. Fruiting of G. punctatum and T. meridionalis was continued with a high percentage of unripe fruits. The higher fruiting was shown in the wet season. Both species presented seed rain during all the study. G. punctatum had higher seed rain with an average of 169/m 2 ; while t. meridionalis only 50 seeds/m 2 . Most abundance of G. punctatums seeds was recorded in the dry season, while for T. meridionalis in wet season. In spite of low seed rain for T. meridionalis it showed a high percentage of viable seeds. G. punctatum presented more propagules that could explain the high number of individuals by area. Although the number of seeds of T. meridionalis is not very high, it represents a potential for prevalence of this specie and the need of looking for factors that to block the persistence of this propagules.

  11. Don't let the world become too small” – How patients with advanced cancer and their significant others cope with transitions during the last year of life. A qualitative study

    Science.gov (United States)

    Chabloz-Süssenbach, Christiane; Sailer Schramm, Monique; Stoll, Hansruedi; Spirig, Rebecca

    2016-07-01

    Background: In the last year of life, persons with advanced cancer and their significant others are affected by several transitions. They perform psychological adjustment processes during transformation. This requires strategies for patients and their significant others. Research in German about this theme is missing. Aim: We explored the experiences with illness management during transitions in the last year of life of patients with advanced cancer and their significant others. Method: In this qualitative study, we conducted structured interviews with five dyads, consisting of persons with Karnofsky Index ≥ 60 % and life expectancy of six to twelve months as well as their significant others. To interpret the interviews, we used qualitative content analysis according to Mayring. Results: The main theme “Don't let the world become too small” expresses that limitations diminished the lifeworld and the participants struggled against this process. This is revealed in three categories: “Being shocked by diagnosis – realigning again”, “Bearing limitations and loss – finding new ways in daily life”, “Living in uncertainty – holding out together”. Conclusions: Patients and significant others live in changing lifeworlds caused by transitions. Health care professionals should be attentive and may gain deeper knowledge about transitions. Further research in German-speaking contexts will help to improve nursing care and psychooncological interventions.

  12. Considerações sobre o pensamento estético de Don Ellis: inovação/tradição 87 e o elemento indiano em The Tihai

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    Leandro Gumboski

    2013-12-01

    Full Text Available Ao intitular uma peça que integra o álbum Shock Treatment, lançado em 1968, como The Tihai, o compositor, trompetista e band leader norte-americano Don Ellis fez referência direta à música clássica indiana, mais precisamente a uma estrutura desta – tihai. A busca de um elemento pré-existente para inovar sua própria linguagem, bem como o jazz de maneira geral, apresenta forte coerência com a dialética inovação/tradição, frequentemente apontada na concepção ellisiana. À luz dos escritos e depoimentos de Ellis, este artigo investiga o seu pensamento estético, com atenção ao contexto musical ao qual ele pertenceu: o jazz. Posteriormente, analisa-se o tihai indiano em The Tihai, que abriu caminho para aquilo que o compositor chamava de “novos ritmos” (ELLIS, 1972, i.e., complexidades rítmicas que se tornaram características de sua linguagem musical. Conclui-se que a partir de tal composição Ellis concretizou seus ideais estéticos.

  13. Нижнедонская контактная зона взаимодействия номадов и оседлого населения в первые века н.э. / Lower Don Contact Zone of interaction of Nomads and the Settled Population in the first centuries CE

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    Vdovchenkov E.V.

    2017-12-01

    Full Text Available The article is devoted to one of the most pressing problems of the history of the ancient Northern Black Sea region: the situation in the Lower Don contact zone in the first centuries CE. Its main peculiarity was the mutual influence of the ancient and barbarian Iranian world on the one hand, and the interaction of the sedentary and nomadic population of the region on the other. In the Lower Don from the first to the third centuries CE, lived three different ethno-cultural groups: the nomads of Sarmatia, the Greeks (inhabitants of Tanais, and the Meotians (in the ancient settlements on the right and left banks of Don. Based on the analysis of archaeological data and written sources, the features of the Lower Don contact zone are presented as a result of evolution in three interconnected planes: economic, ethno-cultural, and political. Attention is paid to the problem of the Tanais and Meotian fortifications, as well as to the identification of specific cultural practices that arisen in the Lower Don contact zone.

  14. Polimorfismo do gene tp53 no códon 72 em pacientes com suspeita de LMC Codon 72 polymorphism of the TP53 gene in patients suspected to have CML

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    Camila S. Hamú

    2007-12-01

    Full Text Available A leucemia mielóide crônica (LMC é uma doença proliferativa do sistema hematopoiético, caracterizada pela expansão clonal de uma célula-tronco primitiva e pluripotente denominada stem cell. Este tipo de leucemia está associado, em 90% dos casos, à translocação t(9;22(q34;q11. Essa alteração cromossômica estrutural codifica para uma proteína quimérica BCR-ABL, que confere às células leucêmicas uma alta resistência à morte, independente do agente indutor desse processo. A proteína p53 é uma reguladora transcricional induzida por danos no DNA, fato que resulta na parada do ciclo celular com conseqüente ativação de mecanismos de reparo ou mesmo na indução à apoptose. As mutações no gene TP53 são as alterações genéticas mais comuns em tumores malignos humanos. O presente estudo teve como objetivo genotipar e determinar a freqüência alélica do polimorfismo do TP53 no códon 72 (arginina - Arg e prolina - Pro, em pacientes com suspeita de LMC, pela Reação em Cadeia da Polimerase. Desta forma, os resultados indicaram que 73,4% (23/30 dos pacientes apresentaram homozigose para arginina (Arg/Arg e 26,6% (7/30 heterozigose (Arg/Pro. Não foi encontrado nenhum paciente homozigoto para prolina (Pro/Pro. Os resultados obtidos sugerem que o polimorfismo do gene TP53 no códon 72 não é um fator de risco importante para a iniciação, promoção e progressão da LMC.Chronic myeloid leukemia (CML is a proliferative disorder of the hematopoietic system characterized by clonal expansion of a primitive and pluripotent stem cell. In this type of leukemia, up to 90% of all cases is associated to a specific chromosomal translocation, t(9;22(q34;q11. The genomic alteration results in a chimeric protein, BCR-ABL, that confers a high resistance leukemia cells to death, independent of the induction mechanism of this process. Protein p53 is a transcriptional factor expressed after DNA damage which ceases cell cycle progression and

  15. Butanol fraction of Parkia biglobosa (Jacq.) G. Don leaves enhance pancreatic β-cell functions, stimulates insulin secretion and ameliorates other type 2 diabetes-associated complications in rats.

    Science.gov (United States)

    Ibrahim, Mohammed Auwal; Habila, James Dama; Koorbanally, Neil Anthony; Islam, Md Shahidul

    2016-05-13

    Ethnopharmacological surveys have reported that Parkia biglobosa (Jacq.) G. Don (Leguminosae) is among the plants commonly used in the traditional management of diabetes mellitus in Nigeria and Togo. This study investigated the anti-diabetic activity of the butanol fraction of P. biglobosa leaves (PBBF) in a type 2 diabetes (T2D) model of rats and a possible bioactive compound in the fraction. T2D was induced by feeding rats with a 10% fructose solution ad libitum for two weeks followed by an intraperitoneal injection of 40mg/kg body weight streptozotocin and the animals were orally treated with 150 and 300mg/kg BW of the PBBF for five days in a week. Another group of rats was non-diabetic but similarly administered with 300mg/kg BW of the PBBF. Food and fluid intakes, body weight changes and blood glucose levels were monitored during the experiment while other relevant diabetes-associated parameters were measured at the end of the experiment. The PBBF treatments significantly (P<0.05) decreased the blood glucose levels and improved the glucose tolerance ability compared to untreated diabetic rats. Furthermore, the treatments were found to improve pancreatic β cell function (HOMA-β), stimulate insulin secretions, decrease insulin resistance (HOMA-IR), restore liver glycogen, ameliorate serum dyslipidaemia and prevent hepatic and renal damages compared to untreated diabetic rats. Phytochemical analysis of the fraction led to the isolation of lupeol which inhibited α-glucosidase and α-amylase in non-competitive and uncompetitive inhibition patterns respectively. It was concluded that PBBF possessed remarkable anti-T2D activity which is mediated through modulation of β-cell function and stimulation of insulin secretion and the lower dose (150mg/kg BW) was found optimum for anti-T2D activity compared to the high dose (300mg/kg BW) in this study. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  16. Estudo do polimorfismo genético no gene p53 (códon 72 em câncer colorretal Role of the genetic polymorphism of p53 (codon 72 gene in colorectal cancer

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    Jacqueline Miranda de Lima

    2006-03-01

    Full Text Available RACIONAL: Polimorfismos genéticos são variações genéticas que podem ocorrer em seqüências codificadoras e não-codificadoras, levando a alterações qualitativas e/ou quantitativas das proteínas em questão. O p53 é o gene mais comumente alterado no câncer humano. O polimorfismo desse gene no códon 72 ocorre por substituição de uma base e tem sido associado a maior risco de câncer. OBJETIVO: Determinar a possível associação entre o polimorfismo no códon 72 (72 arginina/prolina do gene p53 e câncer colorretal. CASUÍSTICA E MÉTODOS: Foram avaliados em 100 pacientes com câncer colorretal e em 100 indivíduos sem câncer, pareados quanto ao sexo idade, o hábito de fumar, o etilismo e no grupo caso o estádio, o grau de diferenciação e a evolução da doença. O genótipo (72 arginina/prolina foi determinado por PCR, utilizando-se primers (seqüências de nucleotídeos específicos. RESULTADOS: O genótipo homozigoto arginina/arginina foi prevalente em 56% no grupo controle e em 58% no grupo caso. Não se observou diferença entre os dois grupos. No estádio IV este genótipo foi mais freqüente quando comparado ao estádio I (80% versus 14%. Não se observou diferença entre as variações do genótipo e fumo, álcool, evolução clínica ou grau de diferenciação. CONCLUSÃO: A prevalência do genótipo arginina/arginina foi a mais freqüente nos dois grupos. Não foi encontrada correlação entre maior risco de câncer e o polimorfismo no códon 72 prolina/arginina do gene p53. Apesar do pequeno número de doentes com câncer em estádio avançado (IV, estes tiveram maior prevalência do genótipo arginina/arginina.BACKGROUND: Polymorphisms are genetic variations that can occur in sequences of codons, leading to defective proteins. p53 is the most commonly gene affected in human cancer. The polymorphism of this gene occurs by a substitution of a base in codon 72 and may increase the risk of cancer. AIM: To investigate the

  17. Estimación de un modelo hedónico para el precio de los predios en las áreas de Pozos Colorados, Bello Horizonte y Don Jaca de la ciudad de Santa Marta D.T.C.H, Colombia

    Directory of Open Access Journals (Sweden)

    Edwin Causado Rodríguez

    2014-01-01

    Full Text Available El presente trabajo tiene como finalidad identificar mediante la aplicación del método de precios hedónicos expresado en un modelo econométrico, las variables determinantes del valor de los predios de las áreas de Pozos Colorados, Bello Horizonte y Don Jaca de la ciudad de Santa Marta, incluyendo la variable ambiental en la cuantificación económica de este. Este estudio, es de gran importancia debido a que en Colombia y, sobre todo, en el departamento del Magdalena, concretamente en la ciudad de Santa Marta, no se han realizado estudios de valoración económica con inclusión de la variable ambiental y tampoco de cuantificación de impacto ambiental en el valor de un predio expuesto a una externalidad del sector productivo. A través de la metodología de precios hedónicos, se pretendió evaluar información actualizada de precios de predios para el año 2005; identificando seis variables, de las cuales sólo una resultó no tener ninguna relevancia, ni incidencia sobre el precio de los predios del área de estudio, siendo esta la de estrato. En cuanto a las cinco variables restantes; superficie del terreno (M2, área construida (M2, proximidad al puerto de PRODECO, proximidad a la playa y proximidad a vía de acceso principal y de circulación de tractomulas que transportan carbón (Troncal del Caribe, mostraron tener incidencias sobre el precio del suelo de las área de Pozos Colorados, Bello Horizonte y Don Jaca de la ciudad de Santa Marta D.T.C.H, incluyendo la variable ambiental en el precio de estos predios.Palabras Clave: Precios Hedónicos; Precio del Suelo; Valoración económica; Impacto Ambiental Carbón; Pozos Colorados; Bello Horizonte; Don Jaca. Estimate of a hedonistic model for the Price of properties in the áreas of Pozos Colorados, Bello Horizonte and Don Jaca of the city of Santa Marta D.T.C.H, Colombia.AbstractThe purpose of this article is to identify the determining variables of the price of real estate in the

  18. Mineralización del nitrógeno, carbono y actividad enzimática del suelo en un bosque de Nothofagus obliqua (Mirb Oerst y una plantación de Pinus radiata D. Don. del centro-sur de Chile Nitrogen and carbon mineralization and enzyme activity in soils of Nothofagus obliqua (Mirb Oerst stands and Pinus radiata D. Don plantation in south-central Chile

    Directory of Open Access Journals (Sweden)

    YESSICA RIVAS

    2009-03-01

    Full Text Available En Chile, el establecimiento de plantaciones comerciales de rápido crecimiento ha sido sostenido en las últimas décadas mediante la sustitución de bosques nativos y conversión de suelos agrícolas. Pinus radiata D. Don es la principal especie productiva, debido a su crecimiento acelerado y adaptabilidad al clima y los suelos. En el presente estudio se plantea que la actividad biológica del suelo es variable a través del año, en respuesta a variaciones de precipitación, temperatura y contenido de humedad de suelo y que el cambio de uso de suelo desde un bosque templado de Nothofagus obliqua (Mirb Oerst a una plantación con coniferas exóticas, modifica la química del suelo y consecuentemente los procesos de N-min, C-min y la actividad biológica del suelo. Esta hipótesis fue examinada en un bosque de N. obliqua y una plantación de P. radiata del centro-sur de Chile (40°07' S, 72° O. Se evaluó mensualmente la tasa mineralización de nitrógeno (N-min, cabono (C-min y la actividad enzimática potencial del suelo (ureasa, proteasa e hidrólisis de la fluoresceína diacetato entre septiembre 2003 y mayo 2005. Los resultados demuestran que los niveles de las variables de actividad biológica del suelo fueron significativamente diferentes entre las parcelas de bosque y plantación (Lambda de Wilk = 0,022; F 5,80 = 733; P In Chile, commercial forests plantations have increased during the last decades due in part to replacement of native forests and conversion of agricultural soils. Pinus radiata D. Don has been the main tree planted, due to its rapid growth and adaptability. In the present study we proposed that biological activity varies along the year due to changes of precipitation, temperature and soil water content and mainly because the conversion of native forest to exotic P. radiata plantations alters the soil chemistry, N and C mineralization and the potential enzymatic activity in these soils. This hypothesis was examined in a

  19. El valor jurídico de un libro : Don Quixote de la Mancha (con Epílogo sobre su precio originario y las economías de una Cátedra universitaria hace trescientos años

    Directory of Open Access Journals (Sweden)

    Germán José maría Barreiro González

    2007-12-01

    Full Text Available Miguel de Cervantes Saavedra, se inscribe en la nómina de los literatos clásicos y universales que combinaron de manera magistral la Literatura y el Derecho. De todos es conocida la omnipresencia de lo jurídico en la obra de Cervantes. Pero la que muestra una irrupción extensa del autor en el mundo del Derecho es la conocida popularmente como "Don Quixote de La Mancha': Derechos de ta persona (la defensa de la vida, la libertad, la igualdad natural de los hombres; Derecho de Gentes (la concepción de la guerra y la paz, la humanización de la guerra; Monarquía, Estados y República; Gobierno y Administración de justicia (fundamentalmente la tarea de Sancho Panza como Gobernador de la Insula de Barataria; Derecho Penal (delitos y penas, antropología criminal; Derecho Privado (propiedad, responsabilidad por daños, familia; y Derecho del Trabajo (trabajos, oficios y servicios de la época, la relación jurídica entre don Quijote y Sancho. A modo de Epilogo, la financiación de los libros de una cátedra universitaria y el coste al público, en la época, de la Novela inmortalMiguel de Cervantes Saavedra is a classic and universal writer who wisely combined Literature and Law. It is very well known that legal aspects are present in Cervantes' works, mainly in Don Quixote: Rights of the person (life defence, freedom, natural equality of men; lus Gentium (the conception of war and peace, war humanization; Monarchy, States and Republic; Government and Justice Administration (mainly Sancho Panza's task as governor of the "Insula de Barataria"; Criminal Law (criminal offences and sentences, criminal anthropology; Private Law (property, damage responsibility, family; and Labour Law (jobs and services of the time, legal relationship between don Quixote and Sancho. As an Epilogue, the financing of books of a University chair and the public cost of the time of the inmortal Novel are offered

  20. Effect of aluminum on the growth and nutrient uptake in cryptomeria japonica D.Don and Chamaecyparis obtusa Sieb. et Zucc.; Sugi oyobi hinoki no ikusei to yobun kyushu ni oyobosu aluminium no eikyo

    Energy Technology Data Exchange (ETDEWEB)

    Kono, Y; Matsumura, H; Kobayashi, T [Central Research Institute of Electric Power Industry, Tokyo (Japan)

    1995-09-10

    Two-year-old seedlings of Sugi (Japanese cedar: Cryptomeria japonica D. Don) and Hinoki (Japanese cypress: Chamaecyparis obtusa Sieb. et Zucc.) were grown for 4 months in 1/5 Hoagland`s No.2 nutrient culture solution containing aluminum chloride in the concentration range of 0.5 to 20 mM within the pH range of 3.5 to 4.0. Aluminium supplied at or below 1 mM of Al had no effect on the mortality of these species. However, the increase Al concentration higher than 2 mM increased the mortality. While they showed significant growth reduction at or higher Al concentration of 5 mM, there were no difference in growth response to Al between the two species in this experiment. While Al contents in leaf and root significantly increased with increasing Al concentration in the solution, contents of Ca, Mg and P in leaf decreased. Roof p content in Sugi increased with the increase of Al concentration in the solution, while no such change was observed in Hinoki root. This result suggests that Al might make phosphate immobile or inviolable form in Sugi root and this might lead to the reduced translocation of P into the leaf. In contrast, Al did not interfere with the uptake of phosphate in the root, however, it might interrupt phosphate transport into leaf from root system in Hinoki. The Al concentration such as 5 mM in the root sphere induced growth reductions in Sugi and Hinoki, with no significant difference in the response between the two species. This concentration was much higher than those reported in the field crops, vegetables and/or herbs. Thus, if soil acidification will be induced by acidic deposition in future, these herbaceous plants will be influenced faster than the conifer trees. This also means that ground vegetation change will be observed earlier than the conifer decline by the soil acidification stress. 23 refs., 5 figs., 3 tabs.

  1. THE RELATIONSHIP BETWEEN OTTOMAN AND SPAIN IN THE END OF XVIIIth CENTURY / XVIII. YÜZYILIN SONUNDA OSMANLI-İSPANYA İLİSKİLERİ: İLK İSPANYOL DAİMİ ELÇİSİ DON JUAN DE BOULIGNY ÖRNEĞİ

    Directory of Open Access Journals (Sweden)

    Dr. Hüseyin Serdar TABAKOĞLU

    2008-12-01

    Full Text Available The Ottoman and Spanish empires struggled forthe control of the Mediterranean during the 16th centurybut they withdrew their forces from this conflict for otherpriorities at the end of the century. In the 17th and 18thcenturies their power decreased and classical institutionswere damaged. The Ottomans and Spanish tried torestore their former glory by reforming their institutions.The Ottomans and Spanish re-established their politicaland economic relations and signed a treaty of neutralityin 1782. Thus, the Ottomans had an important supportagainst the Russian presence in the Mediterranean.Spain, after re-establishing relations with the Ottomans,appointed their first permanent ambassador to Đstanbuland Don Juan de Bouligny started his mission in 1783.He worked to establish the embassy, find translators anddragomans, release the Spanish prisoners in theOttoman lands. After the French Revolution, a struggleoccured between the pro-French and anti-Frenchdiplomats in Đstanbul. Spain signed an alliance with theRevolutionary France in 1796, and the Spanish vesselsjoined the French armada to occupy Egypt. Boulignyordered the Spanish consulates in the Mediterranean toassist the French armada. That was why, the firstSpanish permanent representative in Đstanbul, Don Juande Bouligny was declared persona non grata and deportedin 1799. However, friendly relations with Spain waspreserved.

  2. Influencia del deterioro incipiente producido por el hongo de pudrición parda Serpula lacrymans, sobre las propiedades mecánicas de compresión normal y paralela a la fibra en madera de Pinus radiata D. Don

    Directory of Open Access Journals (Sweden)

    Pereira, A.

    2011-03-01

    Full Text Available Several buildings and structures of wood are attacked by rot fungi, leading in some cases, slight weight losses that result in reductions in the strength properties of the material. In this work was evaluated the influence of early rot decay in wood, in mechanical properties of normal and parallel compression. For this, were inoculated samples of Pinus radiata D. Don with brown rot fungi Serpula Lacrymans. These samples were tested in three differents periods of fungal exposure. The results identified a significant decrease in percentage of the properties under study.Diversas edificaciones y estructuras construidas en madera son atacadas por hongos de pudrición, provocando en algunos casos, leves pérdidas de peso que se traducen en disminución en las propiedades resistentes del material. En este trabajo se evaluó la influencia de estados incipientes de pudrición en madera, en las propiedades mecánicas de compresión paralela y compresión normal. Para esto, se inocularon probetas de Pinus radiata D. Don. con el hongo de pudrición parda Serpula lacrymans, las cuales fueron posteriormente ensayadas mecánicamente en tres diferentes períodos de exposición fúngica. Los resultados obtenidos determinaron una importante disminución porcentual de las propiedades bajo estudio.

  3. Don't Take This with That!

    Medline Plus

    Full Text Available ... tips: Ask your pharmacist or other health care professional if you can have fresh grapefruit or grapefruit ... Inspections & Compliance Federal, State & Local Officials Consumers Health Professionals Science & Research Industry Scroll back to top Popular ...

  4. Don't Take This with That!

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  5. Don't Take This with That!

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    Full Text Available ... and tangelos (a cross between tangerines and grapefruit) affect the same enzyme as grapefruit juice, so avoid ... feeds Follow FDA on Twitter Follow FDA on Facebook View FDA videos on YouTube View FDA photos ...

  6. Don't Take This with That!

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    Full Text Available ... Medical Devices Radiation-Emitting Products Vaccines, Blood & Biologics Animal & Veterinary Cosmetics Tobacco Products Drugs Home Drugs Resources ... Medical Devices Radiation-Emitting Products Vaccines, Blood & Biologics Animal & Veterinary Cosmetics Tobacco Products

  7. It don't mean a thing..

    DEFF Research Database (Denmark)

    Vuust, Peter; Roepstorff, Andreas; Wallentin, Mikkel

    2006-01-01

    influence on the listener, particularly when the experience of the original meter is maintained during the counter pulse. We here demonstrate that Brodmann area 47, an area associated with higher processing of language, is activated bilaterally when musicians tap the main pulse in a polymetric context where...... the music emphasizes a counter meter. This suggests that the processing of metric elements of music relies on brain areas also involved in language comprehension. We propose that BA47 is involved in general neuronal processing of temporal coherence subserving both language and music...

  8. When Attitudes Don't Predict Behavior

    DEFF Research Database (Denmark)

    Bhattacherjee, Anol; Sanford, Clive Carlton

    2006-01-01

    This study introduces the concept of "attitude strength" to explain why some IT users' attitudes are not strongly related to their usage behaviors. We review the attitude strength literature, employ the elaboration likelihood model to theorize personal relevance and related expertise as two salient...... dimensions of attitude strength in the IT usage context, and postulate a research model to capture the moderating effects of these constructs on the attitude-behavior relationship. The hypothesized effects are empirically tested using a longitudinal survey of document management system usage among staff...

  9. Don't Take This with That!

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    Full Text Available ... to enjoy these tasty mounds without compromising your safety. But until the new fruit containers start to ... FDA Archive Combination Products Advisory Committees Regulatory Information Safety Emergency Preparedness International Programs News & Events Training & Continuing ...

  10. Don't Take This with That!

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    Full Text Available ... Continuing Education Inspections & Compliance Federal, State & Local Officials Consumers Health Professionals Science & Research Industry Scroll back to ... an Adverse Event MedWatch Safety Alerts News Releases Consumer Updates About FDA Contact FDA Browse by Product ...

  11. Don't Take This with That!

    Medline Plus

    Full Text Available ... the drug, which can potentially cause serious problems. Help may be on the way Scientists are currently ... Updated: 12/17/2015 Note: If you need help accessing information in different file formats, see Instructions ...

  12. Dogs Don't Need Calculus

    Science.gov (United States)

    Bolt, Mike

    2010-01-01

    Many optimization problems can be solved without resorting to calculus. This article develops a new variational method for optimization that relies on inequalities. The method is illustrated by four examples, the last of which provides a completely algebraic solution to the problem of minimizing the time it takes a dog to retrieve a thrown ball,…

  13. Don't Take This with That!

    Medline Plus

    Full Text Available ... Food and Drug Administration that can have negative interactions with grapefruit. As little as one cup of ... medicine interacts with grapefruit juice. Related Information Drug Interactions: What You Should Know More in Special Features ...

  14. Don't Take This with That!

    Medline Plus

    Full Text Available ... active ingredient, grapefruit can reduce the effectiveness of a drug or worse, create potentially dangerous drug levels in the body. Grapefruit can interfere with transporters ...

  15. Don't Take This with That!

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    Full Text Available ... Emergency Preparedness International Programs News & Events Training & Continuing Education Inspections & Compliance Federal, State & Local Officials Consumers Health Professionals Science & Research Industry Scroll back to top Popular Content Home ...

  16. Don't Take This with That!

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    Full Text Available ... Continuing Education Inspections & Compliance Federal, State & Local Officials Consumers Health Professionals Science & Research Industry Scroll back to top Popular Content Home Latest Recalls Report an Adverse Event MedWatch Safety Alerts News Releases ...

  17. Don’t Trust the Big Man

    Science.gov (United States)

    2008-06-06

    on the scholar questioned, these entities began as either natural alliances of people already united by colocation, culture , ethnicity, religion and...anger to provide a channel for the pent-up anger at a failing government. This is where the tribal culture becomes interesting. The Big Man can find...Zulu, Dinka, and Maasai; the Shona and Yoruba and Somali - militates against the very idea of borders drawn through tribal and nomadic areas by the

  18. Don't Tie Me Down!

    Science.gov (United States)

    Minges, Norma; And Others

    1978-01-01

    Authors provide guidelines for a program utilizing learning stations designed to motivate, stimulate, and guide affective and cognitive education at higher levels of thinking for academically gifted students. This approach to enrichment is defined, and the role of the teacher as facilitator is considered. (SBH)

  19. Don't Take This with That!

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    Full Text Available ... enzymes that break down drugs in your digestive system. This can result in the body absorbing too ... Emergency Preparedness International Programs News & Events Training & Continuing Education Inspections & Compliance Federal, State & Local Officials Consumers Health ...

  20. Don't Take This with That!

    Medline Plus

    Full Text Available ... View FDA videos on YouTube View FDA photos on Flickr FDA Archive Combination Products Advisory Committees Regulatory Information Safety Emergency Preparedness International Programs News & Events Training & Continuing Education Inspections & Compliance Federal, State & Local Officials Consumers Health ...

  1. Why Don't They Understand Us?

    Science.gov (United States)

    Kvasz, Ladislav

    The aim of the article is to provide teachers some ideas about the development of physical knowledge and to make them more receptive to the differences between their and the students thinking. I want to show, that these differences lie not only in the richness of experience, but also in the structure of this experience. I try to point to some of these differences lying in the content, form and meaningfulness. The article is based on an adapted version of Piaget's model of the growth of physical knowledge. The model represents the changes of semantic understanding, formal language and logical structure of a theory during its historical development. I illustrate the model on the development of classical mechanics, but similar changes can be found also in the history of electrodynamics or quantum mechanics. The central idea of the paper is to use this model of the historical development of physical knowledge in analysis of the cognitive processes in physics education.

  2. Why entrepreneurs don't scale.

    Science.gov (United States)

    Hamm, John

    2002-12-01

    It's well known that many executives who excel at starting businesses or projects fizzle out--in other words, they fail to "scale"--as their ventures grow. But the reasons have remained fuzzy. In this article, leadership coach John Hamm identifies four management tendencies that work for small-company or business-unit leaders but become Achilles' heels as those individuals try to run larger organizations. The first tendency is loyalty to comrades. In entrepreneurial mode, you need to lead as though you're in charge of a combat unit on the wrong side of enemy lines. But blind loyalty can become a liability in managing a complex organization. The second tendency, task orientation, is critical in driving toward a big product launch, but excessive attention to detail can cause a large organization to lose sight of its long-term goals. The third tendency, single-mindedness, is important in a visionary unleashing a revolutionary product or service on the world but can limit the company's potential as it grows. And the fourth tendency, working in isolation, is fine for the brilliant scientist focused on an ingenious idea. But it's disastrous for a leader whose expanding organization increasingly relies on many other people. Leaders who scale deal honestly with problems and quickly weed out nonperformers. They see past distractions and establish strategic priorities. They learn how to deal effectively with diverse employees, customers, and external constituencies. And, most important, they make the company's continuing health and welfare their top concern.

  3. Don't Take This with That!

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    Full Text Available ... Health and Human Services U.S. Food and Drug Administration A to Z Index Follow FDA En Españ ... drugs known to the U.S. Food and Drug Administration that can have negative interactions with grapefruit. As ...

  4. Don't Take This with That!

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    Full Text Available ... reaches the bloodstream and the patient receives no benefit. Grapefruit can also interfere with enzymes that break ... Emergency Preparedness International Programs News & Events Training & Continuing Education Inspections & Compliance Federal, State & Local Officials Consumers Health ...

  5. Don't Take This with That!

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    Full Text Available ... safe to mix with medications. In the near future you may be able to enjoy these tasty ... if you can have other juices with the medicine. Read the Medication Guide or patient information sheet ...

  6. Don't Take This with That!

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    Full Text Available ... squeeze…especially when combining grapefruit with medicines. While it can be part of a balanced and nutritious diet, grapefruit can have serious consequences when taken with certain medications. Currently, there are ...

  7. Don't Take This with That!

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    Full Text Available ... are currently working on breeding hybrid grapefruits that will be safe to mix with medications. In the ... If it’s OK to have grapefruit juice, there will be no mention of it in the guide ...

  8. Don't Take This with That!

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    Full Text Available ... mounds without compromising your safety. But until the new fruit containers start to arrive, follow these tips: ... Website Policies U.S. Food and Drug Administration 10903 New Hampshire Avenue Silver Spring, MD 20993 1-888- ...

  9. Don't Take This with That!

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    Full Text Available ... FDA Submit search Popular Content Home Food Drugs Medical Devices Radiation-Emitting Products Vaccines, Blood & Biologics Animal & ... by Product Area Product Areas back Food Drugs Medical Devices Radiation-Emitting Products Vaccines, Blood & Biologics Animal & ...

  10. Don't Take This with That!

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    Full Text Available ... near future you may be able to enjoy these tasty mounds without compromising your safety. But until the new fruit containers start to arrive, follow these tips: Ask your pharmacist or other health care ...

  11. Don't Kiss a Frog!

    Centers for Disease Control (CDC) Podcasts

    2009-08-04

    This CDC Kidtastics podcast discusses the danger of reptiles and amphibians carrying and spreading Salmonella and how to prevent infection.  Created: 8/4/2009 by National Center for Zoonotic, Vector-Borne, and Enteric Diseases (NCZVED).   Date Released: 8/4/2009.

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  13. Moral: Don't Ignore Harassment.

    Science.gov (United States)

    Sendor, Benjamin

    1996-01-01

    Last year, the U.S. Court of Appeals for the 11th Circuit ruled in "Davis" that a student can sue for damages if school officials know a student is being sexually harassed but fail to intervene. (MLF)

  14. Don't Trust the Big Man

    National Research Council Canada - National Science Library

    Coerr, Stanton S

    2008-01-01

    .... A full-length analysis of the Democratic Republic of the Congo and its full-scale insurgencies since 1960 -- at the hands of Big Man leaders Lumumba, Mobutu, and Kabila -- provide object lessons...

  15. Don't Take This with That!

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    Full Text Available ... DO NOT TAKE WITH GRAPEFRUIT” or has similar words, heed the warning. It can save you a ... Products Advisory Committees Regulatory Information Safety Emergency Preparedness International Programs News & Events Training & Continuing Education Inspections & Compliance ...

  16. Don't Take This with That!

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    Full Text Available ... of problems. How it does or doesn’t work Depending on the active ingredient, grapefruit can reduce ... follow these tips: Ask your pharmacist or other health care professional if you can have fresh grapefruit ...

  17. Don't Double Up on Acetaminophen

    Science.gov (United States)

    ... re at the store deciding which product to buy, check the 'Drug Facts' label of OTC cold, cough and flu ... If you’re still not sure which to buy, ask the pharmacist for advice. FDA has an ... medicines containing acetaminophen accounted for nearly half of all ...

  18. Don't panic - Just watch TV

    International Nuclear Information System (INIS)

    McRoberts, Doug

    1995-01-01

    This case study describes a true story emphasising the role of TV which have become a very powerful tool, developed very fast resulting in the fact that people believe TV more than real events. TV gets very close, very quickly. Media concentrate on human tragedy, media resource is overwhelmingly large and very rapid; images and sounds of death, pain and worry are powerful. Within hours, explanations and graphic analysis are broadcast - with or without official input. Four videotapes are described including the lessons learned. Result is a vastly-improved emergency PR response plan. Developing it has enhanced trust and credibility with local communities and with the national and regional media organisations

  19. Do's and Don'ts for Liposuction

    Science.gov (United States)

    ... for Every Season How to Choose the Best Skin Care Products In This Section Dermatologic Surgery What is dermatologic ... for Every Season How to Choose the Best Skin Care Products Do's and don’ts for liposuction Don’t ...

  20. Don't Take This with That!

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    Full Text Available ... breeding hybrid grapefruits that will be safe to mix with medications. In the near future you may ... About FDA Contact FDA Browse by Product Area Product Areas back Food Drugs Medical Devices Radiation-Emitting ...