Real-Time Application Performance Steering and Adaptive Control

National Research Council Canada - National Science Library

Reed, Daniel

2002-01-01

.... The objective of the Real-time Application Performance Steering and Adaptive Control project is to replace ad hoc, post-mortem performance optimization with an extensible, portable, and distributed...

Real-time performance monitoring and management system

Science.gov (United States)

Budhraja, Vikram S [Los Angeles, CA; Dyer, James D [La Mirada, CA; Martinez Morales, Carlos A [Upland, CA

2007-06-19

A real-time performance monitoring system for monitoring an electric power grid. The electric power grid has a plurality of grid portions, each grid portion corresponding to one of a plurality of control areas. The real-time performance monitoring system includes a monitor computer for monitoring at least one of reliability metrics, generation metrics, transmission metrics, suppliers metrics, grid infrastructure security metrics, and markets metrics for the electric power grid. The data for metrics being monitored by the monitor computer are stored in a data base, and a visualization of the metrics is displayed on at least one display computer having a monitor. The at least one display computer in one said control area enables an operator to monitor the grid portion corresponding to a different said control area.

Underwater Time Service and Synchronization Based on Time Reversal Technique

Science.gov (United States)

Lu, Hao; Wang, Hai-bin; Aissa-El-Bey, Abdeldjalil; Pyndiah, Ramesh

2010-09-01

Real time service and synchronization are very important to many underwater systems. But the time service and synchronization in existence cannot work well due to the multi-path propagation and random phase fluctuation of signals in the ocean channel. The time reversal mirror technique can realize energy concentration through self-matching of the ocean channel and has very good spatial and temporal focusing properties. Based on the TRM technique, we present the Time Reversal Mirror Real Time service and synchronization (TRMRT) method which can bypass the processing of multi-path on the server side and reduce multi-path contamination on the client side. So TRMRT can improve the accuracy of time service. Furthermore, as an efficient and precise method of time service, TRMRT could be widely used in underwater exploration activities and underwater navigation and positioning systems.

Power/performance trade-offs in real-time SDRAM command scheduling

NARCIS (Netherlands)

Goossens, S.L.M.; Chandrasekar, K.; Akesson, K.B.; Goossens, K.G.W.

2016-01-01

Real-time safety-critical systems should provide hard bounds on an applications’ performance. SDRAM controllers used in this domain should therefore have a bounded worst-case bandwidth, response time, and power consumption. Existing works on real-time SDRAM controllers only consider a narrow range

Reverse transcriptase real-time PCR for detection and quantification of viable Campylobacter jejuni directly from poultry faecal samples

DEFF Research Database (Denmark)

Bui, Thanh Xuan; Wolff, Anders; Madsen, Mogens

2012-01-01

Campylobacter spp. is the most common cause of bacterial diarrhoea in humans worldwide. Therefore, rapid and reliable methods fordetection and quantification of this pathogen are required. In this study, we have developed a reverse transcription quantitative real-time PCR(RT-qPCR) for detection a...

Power/performance trade-offs in real-time SDRAM command scheduling

OpenAIRE

Goossens, S.L.M.; Chandrasekar, K.; Akesson, K.B.; Goossens, K.G.W.

2016-01-01

Real-time safety-critical systems should provide hard bounds on an applications’ performance. SDRAM controllers used in this domain should therefore have a bounded worst-case bandwidth, response time, and power consumption. Existing works on real-time SDRAM controllers only consider a narrow range of memory devices, and do not evaluate how their schedulers’ performance varies across memory generations, nor how the scheduling algorithm influences power usage. The extent to which the number of ...

Research of real-time performance based on VxWorks embedded system

International Nuclear Information System (INIS)

Liu Daming; Li Haiming

2011-01-01

In the research of mechanism and heating efficiency of Ion Cyclotron Range of Frequency (ICRF) heating, data acquisition system with high real-time performance needed. By the means of system logic analyzer, SPY and other relevant software on VxWorks embedded operating system for real-time testing gives real-time data of the system. Real-time level to achieve balances used time and processor idle time, real-time data acquisition, and minimize the interference of external to the system, ensure the system work in its own set of scheduling trajectory. Interrupt switching time and task context switching time meet the system requirements. (authors)

Real-time individualization of the unified model of performance.

Science.gov (United States)

Liu, Jianbo; Ramakrishnan, Sridhar; Laxminarayan, Srinivas; Balkin, Thomas J; Reifman, Jaques

2017-12-01

Existing mathematical models for predicting neurobehavioural performance are not suited for mobile computing platforms because they cannot adapt model parameters automatically in real time to reflect individual differences in the effects of sleep loss. We used an extended Kalman filter to develop a computationally efficient algorithm that continually adapts the parameters of the recently developed Unified Model of Performance (UMP) to an individual. The algorithm accomplishes this in real time as new performance data for the individual become available. We assessed the algorithm's performance by simulating real-time model individualization for 18 subjects subjected to 64 h of total sleep deprivation (TSD) and 7 days of chronic sleep restriction (CSR) with 3 h of time in bed per night, using psychomotor vigilance task (PVT) data collected every 2 h during wakefulness. This UMP individualization process produced parameter estimates that progressively approached the solution produced by a post-hoc fitting of model parameters using all data. The minimum number of PVT measurements needed to individualize the model parameters depended upon the type of sleep-loss challenge, with ~30 required for TSD and ~70 for CSR. However, model individualization depended upon the overall duration of data collection, yielding increasingly accurate model parameters with greater number of days. Interestingly, reducing the PVT sampling frequency by a factor of two did not notably hamper model individualization. The proposed algorithm facilitates real-time learning of an individual's trait-like responses to sleep loss and enables the development of individualized performance prediction models for use in a mobile computing platform. © 2017 European Sleep Research Society.

Dynamic Reconfiguration in Real-Time Systems Energy, Performance, and Thermal Perspectives

CERN Document Server

Wang, Weixun; Ranka, Sanjay

2013-01-01

Given the widespread use of real-time multitasking systems, there are tremendous optimization opportunities if reconfigurable computing can be effectively incorporated while maintaining performance and other design constraints of typical applications. The focus of this book is to describe the dynamic reconfiguration techniques that can be safely used in real-time systems. This book provides comprehensive approaches by considering synergistic effects of computation, communication as well as storage together to significantly improve overall performance, power, energy and temperature.  Provides a comprehensive introduction to optimization and dynamic reconfiguration techniques in real-time embedded systems; Covers state-of-the-art techniques and ongoing research in reconfigurable architectures; Focuses on algorithms tuned for dynamic reconfiguration techniques in real-time systems;  Provides reference for anyone designing low-power systems, energy-/temperature-constrained devices, and power-performance efficie...

Real-time zymography and reverse zymography: a method for detecting activities of matrix metalloproteinases and their inhibitors using FITC-labeled collagen and casein as substrates.

Science.gov (United States)

Hattori, Shunji; Fujisaki, Hitomi; Kiriyama, Tomomi; Yokoyama, Tsukao; Irie, Shinkichi

2002-02-01

Zymography and reverse zymography are widely used techniques for identifying the proteolytic activity of enzymes and the presence of protease inhibitors in polyacrylamide gels. In the current studies, we utilized a fluorescein-isothiocyanate-labeled substrate to develop novel zymographic and reverse zymographic methods for detecting matrix metalloproteinases and tissue inhibitors of the metalloproteinases, respectively. Using a transilluminator, the results can be observed visually without stopping the enzymatic reaction. For this reason, we have named these methods real-time zymography and real-time reverse zymography. These methods have the following advantages compared with conventional protocols: (1) because the reaction can be repeatedly monitored on the polyacrylamide gels, optimization of the incubation time can be achieved without preliminary analyses; (2) higher sensitivity is achieved with a lower amount of substrate than with conventional methods; (3) a semi-quantitative analysis of matrix metalloproteinases is possible. An additional advantage of the real-time reverse zymography is that, because the fluorescence detection is specific for substrate digestion, the inhibitor bands can be easily distinguished from contaminating proteins.

Optimization of the elution buffer and concentration method for detecting hepatitis E virus in swine liver using a nested reverse transcription-polymerase chain reaction and real-time reverse transcription-polymerase chain reaction.

Science.gov (United States)

Son, Na Ry; Seo, Dong Joo; Lee, Min Hwa; Seo, Sheungwoo; Wang, Xiaoyu; Lee, Bog-Hieu; Lee, Jeong-Su; Joo, In-Sun; Hwang, In-Gyun; Choi, Changsun

2014-09-01

The aim of this study was to develop an optimal technique for detecting hepatitis E virus (HEV) in swine livers. Here, three elution buffers and two concentration methods were compared with respect to enhancing recovery of HEV from swine liver samples. Real-time reverse transcription-polymerase chain reaction (RT-PCR) and nested RT-PCR were performed to detect HEV RNA. When phosphate-buffered saline (PBS, pH 7.4) was used to concentrate HEV in swine liver samples using ultrafiltration, real-time RT-PCR detected HEV in 6 of the 26 samples. When threonine buffer was used to concentrate HEV using polyethylene glycol (PEG) precipitation and ultrafiltration, real-time RT-PCR detected HEV in 1 and 3 of the 26 samples, respectively. When glycine buffer was used to concentrate HEV using ultrafiltration and PEG precipitation, real-time RT-PCR detected HEV in 1 and 3 samples of the 26 samples, respectively. When nested RT-PCR was used to detect HEV, all samples tested negative regardless of the type of elution buffer or concentration method used. Therefore, the combination of real-time RT-PCR and ultrafiltration with PBS buffer was the most sensitive and reliable method for detecting HEV in swine livers. Copyright © 2014 Elsevier B.V. All rights reserved.

A real-time reverse transcriptase polymerase chain reaction for detection and quantification of Vesiculovirus

Directory of Open Access Journals (Sweden)

Aline Lavado Tolardo

2016-06-01

Full Text Available Vesiculoviruses (VSV are zoonotic viruses that cause vesicular stomatitis disease in cattle, horses and pigs, as well as sporadic human cases of acute febrile illness. Therefore, diagnosis of VSV infections by reliable laboratory techniques is important to allow a proper case management and implementation of strategies for the containment of virus spread. We show here a sensitive and reproducible real-time reverse transcriptase polymerase chain reaction (RT-PCR for detection and quantification of VSV. The assay was evaluated with arthropods and serum samples obtained from horses, cattle and patients with acute febrile disease. The real-time RT-PCR amplified the Piry, Carajas, Alagoas and Indiana Vesiculovirus at a melting temperature 81.02 ± 0.8ºC, and the sensitivity of assay was estimated in 10 RNA copies/mL to the Piry Vesiculovirus. The viral genome has been detected in samples of horses and cattle, but not detected in human sera or arthropods. Thus, this assay allows a preliminary differential diagnosis of VSV infections.

Real-Time Performance of Hybrid Mobile Robot Control Utilizing USB Protocol

Directory of Open Access Journals (Sweden)

Jacek Augustyn

2015-02-01

Full Text Available This article discusses the problem of usability of the USB 2.0 protocol in the area of real-time control of a mobile robot. Optimization methods of data transfer handling were proposed. The impact of the optimization results on the entire system's performance was examined in practice. As a test-bed, a hybrid system composed of two devices communicating by direct USB connection was implemented. The first of the mentioned devices was a 32-bit SoC micro-system serving as a direct control unit, and the second one was an off-the-shelf PDA providing supervisory control and logging. Due to this design, the system meets regimes of the real-time constraints and maintains continuity of a data stream at a large bandwidth. The real-time performances of subsystems and the entire system were experimentally examined depending on various operating conditions. Thanks to the performed experiments, the dependency of real-time limits on operational parameters has been determined.

QUANTIFICATION OF ENTEROVIRUS AND HEPATITIS A VIRUSES IN WELLS AND SPRINGS IN EAST TENNESSEE USING REAL-TIME REVERSE TRANSCIPTION PCR

Science.gov (United States)

This project involves development, validation testing and application of a fast, efficient method of quantitatively measuring occurrence and concentration of common human viral pathogens, enterovirus and hepatitis A virus, in ground water samples using real-time reverse transcrip...

Real-time Tsunami Inundation Prediction Using High Performance Computers

Science.gov (United States)

Oishi, Y.; Imamura, F.; Sugawara, D.

2014-12-01

Recently off-shore tsunami observation stations based on cabled ocean bottom pressure gauges are actively being deployed especially in Japan. These cabled systems are designed to provide real-time tsunami data before tsunamis reach coastlines for disaster mitigation purposes. To receive real benefits of these observations, real-time analysis techniques to make an effective use of these data are necessary. A representative study was made by Tsushima et al. (2009) that proposed a method to provide instant tsunami source prediction based on achieving tsunami waveform data. As time passes, the prediction is improved by using updated waveform data. After a tsunami source is predicted, tsunami waveforms are synthesized from pre-computed tsunami Green functions of linear long wave equations. Tsushima et al. (2014) updated the method by combining the tsunami waveform inversion with an instant inversion of coseismic crustal deformation and improved the prediction accuracy and speed in the early stages. For disaster mitigation purposes, real-time predictions of tsunami inundation are also important. In this study, we discuss the possibility of real-time tsunami inundation predictions, which require faster-than-real-time tsunami inundation simulation in addition to instant tsunami source analysis. Although the computational amount is large to solve non-linear shallow water equations for inundation predictions, it has become executable through the recent developments of high performance computing technologies. We conducted parallel computations of tsunami inundation and achieved 6.0 TFLOPS by using 19,000 CPU cores. We employed a leap-frog finite difference method with nested staggered grids of which resolution range from 405 m to 5 m. The resolution ratio of each nested domain was 1/3. Total number of grid points were 13 million, and the time step was 0.1 seconds. Tsunami sources of 2011 Tohoku-oki earthquake were tested. The inundation prediction up to 2 hours after the

Cloud computing platform for real-time measurement and verification of energy performance

International Nuclear Information System (INIS)

Ke, Ming-Tsun; Yeh, Chia-Hung; Su, Cheng-Jie

2017-01-01

Highlights: • Application of PSO algorithm can improve the accuracy of the baseline model. • M&V cloud platform automatically calculates energy performance. • M&V cloud platform can be applied in all energy conservation measures. • Real-time operational performance can be monitored through the proposed platform. • M&V cloud platform facilitates the development of EE programs and ESCO industries. - Abstract: Nations worldwide are vigorously promoting policies to improve energy efficiency. The use of measurement and verification (M&V) procedures to quantify energy performance is an essential topic in this field. Currently, energy performance M&V is accomplished via a combination of short-term on-site measurements and engineering calculations. This requires extensive amounts of time and labor and can result in a discrepancy between actual energy savings and calculated results. In addition, the M&V period typically lasts for periods as long as several months or up to a year, the failure to immediately detect abnormal energy performance not only decreases energy performance, results in the inability to make timely correction, and misses the best opportunity to adjust or repair equipment and systems. In this study, a cloud computing platform for the real-time M&V of energy performance is developed. On this platform, particle swarm optimization and multivariate regression analysis are used to construct accurate baseline models. Instantaneous and automatic calculations of the energy performance and access to long-term, cumulative information about the energy performance are provided via a feature that allows direct uploads of the energy consumption data. Finally, the feasibility of this real-time M&V cloud platform is tested for a case study involving improvements to a cold storage system in a hypermarket. Cloud computing platform for real-time energy performance M&V is applicable to any industry and energy conservation measure. With the M&V cloud platform, real-time

Acoustic Performance of a Real-Time Three-Dimensional Sound-Reproduction System

Science.gov (United States)

Faller, Kenneth J., II; Rizzi, Stephen A.; Aumann, Aric R.

2013-01-01

The Exterior Effects Room (EER) is a 39-seat auditorium at the NASA Langley Research Center and was built to support psychoacoustic studies of aircraft community noise. The EER has a real-time simulation environment which includes a three-dimensional sound-reproduction system. This system requires real-time application of equalization filters to compensate for spectral coloration of the sound reproduction due to installation and room effects. This paper describes the efforts taken to develop the equalization filters for use in the real-time sound-reproduction system and the subsequent analysis of the system s acoustic performance. The acoustic performance of the compensated and uncompensated sound-reproduction system is assessed for its crossover performance, its performance under stationary and dynamic conditions, the maximum spatialized sound pressure level it can produce from a single virtual source, and for the spatial uniformity of a generated sound field. Additionally, application examples are given to illustrate the compensated sound-reproduction system performance using recorded aircraft flyovers

Performance Improvement of Real-Time System for Plasma Control in RFX-mod

International Nuclear Information System (INIS)

Luchetta, A.; Manduchi, G.; Soppelsa, A.; Taliercio, C.

2006-01-01

The real-time system for plasma control has been used routinely in RFX-mod since commissioning (mid 2005). It is based on a modular hardware/software infrastructure, currently including 7 VME stations, capable of fulfilling the tight system requirements in terms of input/output channels (> 700 / > 250), real-time data flow (> 2 Mbyte/s), computation capability (> 1 GFLOP/s per station), and real-time constraints (application cycle times rd EPS Conf. on Plasma Physics, Rome Italy, June 19 - 23 2006]. The high flexibility of the system has stimulated the development of a large number of control schemes with progressively increasing requests in terms of computation complexity and real-time data flow, demanding, at the same time, strict control on cycle times and system latency. Even though careful optimisation of algorithm implementation and real-time data transmission have been performed, allowing to keep pace, so far, with the increased control requirements, future developments require to evolve the current technology, retaining the basic architecture and concepts. Two system enhancements are envisaged in the near future. The 500 MHz PowerPC-based Single Board Computer currently in use will be substituted with the 1 GHz version, whereas the real-time communication system will increase in bandwidth from 100 Mbit/s to 1 Gbit/s. These improvements will surely enhance the overall system performance, even if it is not possible to quantify a priori the exact performance boost, since other components may limit the performance in the new configuration. The paper reports in detail on the analysis of the bottlenecks of the current architecture. Based on measurements carried out in laboratory, it presents the results achieved with the proposed enhancements in terms of real-time data throughput, cycle times and latency. The paper analyses in detail the effects of the increased computing power on the components of the control system and of the improved bandwidth in real-time

Multi-processor system for real-time deconvolution and flow estimation in medical ultrasound

DEFF Research Database (Denmark)

Jensen, Jesper Lomborg; Jensen, Jørgen Arendt; Stetson, Paul F.

1996-01-01

of the algorithms. Many of the algorithms can only be properly evaluated in a clinical setting with real-time processing, which generally cannot be done with conventional equipment. This paper therefore presents a multi-processor system capable of performing 1.2 billion floating point operations per second on RF...... filter is used with a second time-reversed recursive estimation step. Here it is necessary to perform about 70 arithmetic operations per RF sample or about 1 billion operations per second for real-time deconvolution. Furthermore, these have to be floating point operations due to the adaptive nature...... interfaced to our previously-developed real-time sampling system that can acquire RF data at a rate of 20 MHz and simultaneously transmit the data at 20 MHz to the processing system via several parallel channels. These two systems can, thus, perform real-time processing of ultrasound data. The advantage...

Towards real-time feedback in high performance speed skating

NARCIS (Netherlands)

van der Eb, Jeroen; Zandee, Willem; van den Bogaard, Timo; Geraets, Sjoerd; Veeger, H.E.J.; Beek, Peter; Potthast, Wolfgang; Niehoff, Anja; David, Sina

2017-01-01

The aim of the current study is to evaluate several performance indicators to be used as real-time feedback in the coming experiments to enhance performance of elite speeds skaters. Six speed skaters, wearing one IMU per skate, collected data over one full training season to evaluate and pinpoint

Hard Real-Time Performances in Multiprocessor-Embedded Systems Using ASMP-Linux

Directory of Open Access Journals (Sweden)

Daniel Pierre Bovet

2008-01-01

Full Text Available Multiprocessor systems, especially those based on multicore or multithreaded processors, and new operating system architectures can satisfy the ever increasing computational requirements of embedded systems. ASMP-LINUX is a modified, high responsiveness, open-source hard real-time operating system for multiprocessor systems capable of providing high real-time performance while maintaining the code simple and not impacting on the performances of the rest of the system. Moreover, ASMP-LINUX does not require code changing or application recompiling/relinking. In order to assess the performances of ASMP-LINUX, benchmarks have been performed on several hardware platforms and configurations.

Hard Real-Time Performances in Multiprocessor-Embedded Systems Using ASMP-Linux

Directory of Open Access Journals (Sweden)

Betti Emiliano

2008-01-01

Full Text Available Abstract Multiprocessor systems, especially those based on multicore or multithreaded processors, and new operating system architectures can satisfy the ever increasing computational requirements of embedded systems. ASMP-LINUX is a modified, high responsiveness, open-source hard real-time operating system for multiprocessor systems capable of providing high real-time performance while maintaining the code simple and not impacting on the performances of the rest of the system. Moreover, ASMP-LINUX does not require code changing or application recompiling/relinking. In order to assess the performances of ASMP-LINUX, benchmarks have been performed on several hardware platforms and configurations.

Development of field-based real-time reverse transcription-polymerase chain reaction assays for detection of Chikungunya and O'nyong-nyong viruses in mosquitoes.

Science.gov (United States)

Smith, Darci R; Lee, John S; Jahrling, Jordan; Kulesh, David A; Turell, Michael J; Groebner, Jennifer L; O'Guinn, Monica L

2009-10-01

Chikungunya (CHIK) and O'nyong-nyong (ONN) are important emerging arthropod-borne diseases. Molecular diagnosis of these two viruses in mosquitoes has not been evaluated, and the effects of extraneous mosquito tissue on assay performance have not been tested. Additionally, no real-time reverse transcription-polymerase chain reaction (RT-PCR) assay exists for detecting ONN virus (ONNV) RNA. We describe the development of sensitive and specific real-time RT-PCR assays for detecting CHIK and ONN viral RNA in mosquitoes, which have application for field use. In addition, we compared three methods for primer/probe design for assay development by evaluating their sensitivity and specificity. This comparison resulted in development of virus-specific assays that could detect less than one plaque-forming unit equivalent of each of the viruses in mosquitoes. The use of these assays will aid in arthropod-borne disease surveillance and in the control of the associated diseases.

High Performance Embedded System for Real-Time Pattern Matching

CERN Document Server

Sotiropoulou, Calliope Louisa; The ATLAS collaboration; Gkaitatzis, Stamatios; Citraro, Saverio; Giannetti, Paola; Dell'Orso, Mauro

2016-01-01

We present an innovative and high performance embedded system for real-time pattern matching. This system is based on the evolution of hardware and algorithms developed for the field of High Energy Physics (HEP) and more specifically for the execution of extremely fast pattern matching for tracking of particles produced by proton-proton collisions in hadron collider experiments. A miniaturized version of this complex system is being developed for pattern matching in generic image processing applications. The design uses the flexibility of Field Programmable Gate Arrays (FPGAs) and the powerful Associative Memory Chip (ASIC) to achieve real-time performance. The system works as a contour identifier able to extract the salient features of an image. It is based on the principles of cognitive image processing, which means that it executes fast pattern matching and data reduction mimicking the operation of the human brain.

Real-Time Shop-Floor Production Performance Analysis Method for the Internet of Manufacturing Things

Directory of Open Access Journals (Sweden)

Yingfeng Zhang

2014-04-01

Full Text Available Typical challenges that manufacturing enterprises are facing now are compounded by lack of timely, accurate, and consistent information of manufacturing resources. As a result, it is difficult to analyze the real-time production performance for the shop-floor. In this paper, the definition and overall architecture of the internet of manufacturing things is presented to provide a new paradigm by extending the techniques of internet of things (IoT to manufacturing field. Under this architecture, the real-time primitive events which occurred at different manufacturing things such as operators, machines, pallets, key materials, and so forth can be easily sensed. Based on these distributed primitive events, a critical event model is established to automatically analyze the real-time production performance. Here, the up-level production performance analysis is regarded as a series of critical events, and the real-time value of each critical event can be easily calculated according to the logical and sequence relationships among these multilevel events. Finally, a case study is used to illustrate how to apply the designed methods to analyze the real-time production performance.

Real Time Synchronization for Creativity in Distributed Innovation Teams

DEFF Research Database (Denmark)

Peitersen, Dennis Kjaersgaard; Dolog, Peter; Pedersen, Esben Staunsbjerg

2009-01-01

In this paper we introduce a synchronization approach for real time collaborative sketching for creativity in distributed innovation teams. We base our approach on reverse AJAX. This way we ensure scalable solution for real time drawing and sketching important in creativity settings....

Comparison of the performance in detection of HPV infections between the high-risk HPV genotyping real time PCR and the PCR-reverse dot blot assays.

Science.gov (United States)

Zhang, Lahong; Dai, Yibei; Chen, Jiahuan; Hong, Liquan; Liu, Yuhua; Ke, Qiang; Chen, Yiwen; Cai, Chengsong; Liu, Xia; Chen, Zhaojun

2018-01-01

A new multiplex real-time PCR assay, the high-risk HPV genotyping real time PCR assay (HR HPV RT-PCR), has been developed to detect 15 high-risk HPV types with respective viral loads. In this report, a total of 684 cervical specimens from women diagnosed with vaginitis were assessed by the HR HPV RT-PCR and the PCR reaction and reverse dot blot (PCR-RDB) assays, using a PCR-sequencing method as a reference standard. A total coincidence of 97.7% between the HR HPV RT PCR and the PCR-RDB assays was determined with a Kappa value of 0.953. The HR HPV RT PCR assay had sensitivity, specificity, and concordance rates (accuracy) of 99.7%, 99.7%, and 99.7%, respectively, as confirmed by PCR-sequencing, while the PCR-RDB assay had respective rates of 98.8%, 97.1%, and 98.0%. The overall rate of HPV infection, determined by PCR-sequencing, in women diagnosed with vaginitis was 49.85%, including 36.26% of single infection and 13.6% of multiple infections. The most common infections among the 15 high-risk HPV types in women diagnosed with vaginitis were HPV-52, HPV-16, and HPV-58, with a total detection rate of 10.23%, 7.75%, and 5.85%, respectively. We conclude that the HR HPV RT PCR assay exhibits better clinical performance than the PCR-RDB assay, and is an ideal alternative method for HPV genotyping. In addition, the HR HPV RT PCR assay provides HPV DNA viral loads, and could serve as a quantitative marker in the diagnosis and treatment of single and multiple HPV infections. © 2017 Wiley Periodicals, Inc.

Performance testing of real-time AI systems using the activation framework

International Nuclear Information System (INIS)

Becker, L.; Duckworth, J.; Laznovsky, A.; Green, P.

1992-01-01

This paper describes methods for automated performance testing of real-time artificial intelligence systems using the Activation Framework software development tool. The Activation Framework is suitable for applications such as the diagnosis of power system failures, which require the interpretation of large volumes of data in real-time. The Activation Framework consists of tools for compiling groups of Expert Systems rules into executable code modules, for automatically generating code modules from high level system configuration descriptions, and for automatically generating command files for program compilation and linking. It includes an operating system environment which provides the code which is common from one real-time AI applications to the next. It also includes mechanisms, described here, for automatic performance testing. The principal emphasis of this paper is on a rule based language which is used to capture performance specifications. This specification is compiled into code modules which are used to automatically test the system. This testing can validate that the system meets performance requirements during development and after maintenance. A large number of tests can be randomly generated and executed and the correctness of the outputs automatically validated. The paper also describes graph directed testing methods to minimize the number of test runs required

Evaluating performance of MARTe as a real-time framework for feed-back control system at tokamak device

Energy Technology Data Exchange (ETDEWEB)

Yun, Sangwon; Lee, Woongryol; Lee, Taegu; Park, Mikyung; Lee, Sangil [National Fusion Research Institute (NFRI), Gwahangno 169-148, Yuseong-Gu, Daejeon 305-806 (Korea, Republic of); Neto, André C. [Associação EURATOM/IST, Instituto de Plasmas e Fusão Nuclear, Instituto Superior Técnico, Universidade Técnica de Lisboa, P-1049-001 Lisboa (Portugal); Wallander, Anders [ITER Organization, Route de Vinon sur Verdon, 13115 St Paul Lez Durance (France); Kim, Young-Kuk, E-mail: ykim@cnu.ac.kr [Chungnam National University, Daejeon 305-764 (Korea, Republic of)

2013-10-15

Highlights: •We measured the performance of MARTe by measuring response time and jitter. •We compared the performance of application with and without MARTe. •We compared the performance of MARTe application on different O/Ss. -- Abstract: The Korea Super conducting Tokamak Advanced Research (KSTAR) is performing the task of “Demonstration and Evaluation of ITER CODAC Technologies at KSTAR” whose objective is the evaluation of real-time technologies for decision making on real-time operating systems (RTOS), real-time frameworks and 10 GbE networks. In this task, the Multi-threaded Application Real-Time executor (MARTe) has been evaluated as a real-time framework for real-time feedback control system. The performance of MARTe has been verified by measuring response time and jitter in a path of feedback control from an analog input of a monitoring system to an analog output of an actuator system. In addition, the evaluation has been performed in terms of applicability of MARTe and its performance depending on types of operating system and tuning of CPU affinity and priority. This paper describes the overview of MARTe as a real-time framework, the results of evaluation performance and its implementation.

Evaluating performance of MARTe as a real-time framework for feed-back control system at tokamak device

International Nuclear Information System (INIS)

Yun, Sangwon; Lee, Woongryol; Lee, Taegu; Park, Mikyung; Lee, Sangil; Neto, André C.; Wallander, Anders; Kim, Young-Kuk

2013-01-01

Highlights: •We measured the performance of MARTe by measuring response time and jitter. •We compared the performance of application with and without MARTe. •We compared the performance of MARTe application on different O/Ss. -- Abstract: The Korea Super conducting Tokamak Advanced Research (KSTAR) is performing the task of “Demonstration and Evaluation of ITER CODAC Technologies at KSTAR” whose objective is the evaluation of real-time technologies for decision making on real-time operating systems (RTOS), real-time frameworks and 10 GbE networks. In this task, the Multi-threaded Application Real-Time executor (MARTe) has been evaluated as a real-time framework for real-time feedback control system. The performance of MARTe has been verified by measuring response time and jitter in a path of feedback control from an analog input of a monitoring system to an analog output of an actuator system. In addition, the evaluation has been performed in terms of applicability of MARTe and its performance depending on types of operating system and tuning of CPU affinity and priority. This paper describes the overview of MARTe as a real-time framework, the results of evaluation performance and its implementation

Detection of SYT-SSX mutant transcripts in formalin-fixed paraffin-embedded sarcoma tissues using one-step reverse transcriptase real-time PCR.

Science.gov (United States)

Norlelawati, A T; Mohd Danial, G; Nora, H; Nadia, O; Zatur Rawihah, K; Nor Zamzila, A; Naznin, M

2016-04-01

Synovial sarcoma (SS) is a rare cancer and accounts for 5-10% of adult soft tissue sarcomas. Making an accurate diagnosis is difficult due to the overlapping histological features of SS with other types of sarcomas and the non-specific immunohistochemistry profile findings. Molecular testing is thus considered necessary to confirm the diagnosis since more than 90% of SS cases carry the transcript of t(X;18)(p11.2;q11.2). The purpose of this study is to diagnose SS at molecular level by testing for t(X;18) fusion-transcript expression through One-step reverse transcriptase real-time Polymerase Chain Reaction (PCR). Formalin-fixed paraffin-embedded tissue blocks of 23 cases of soft tissue sarcomas, which included 5 and 8 cases reported as SS as the primary diagnosis and differential diagnosis respectively, were retrieved from the Department of Pathology, Tengku Ampuan Afzan Hospital, Kuantan, Pahang. RNA was purified from the tissue block sections and then subjected to One-step reverse transcriptase real-time PCR using sequence specific hydrolysis probes for simultaneous detection of either SYT-SSX1 or SYT-SSX2 fusion transcript. Of the 23 cases, 4 cases were found to be positive for SYT-SSX fusion transcript in which 2 were diagnosed as SS whereas in the 2 other cases, SS was the differential diagnosis. Three cases were excluded due to failure of both amplification assays SYT-SSX and control β-2-microglobulin. The remaining 16 cases were negative for the fusion transcript. This study has shown that the application of One-Step reverse transcriptase real time PCR for the detection SYT-SSX transcript is feasible as an aid in confirming the diagnosis of synovial sarcoma.

Spying on real-time computers to improve performance

International Nuclear Information System (INIS)

Taff, L.M.

1975-01-01

The sampled program-counter histogram, an established technique for shortening the execution times of programs, is described for a real-time computer. The use of a real-time clock allows particularly easy implementation. (Auth.)

Outbreak of hepatitis E virus infection in Darfur, Sudan: effectiveness of real-time reverse transcription-PCR analysis of dried blood spots.

Science.gov (United States)

Mérens, Audrey; Guérin, Philippe Jean; Guthmann, Jean-Paul; Nicand, Elisabeth

2009-06-01

Biological samples collected in refugee camps during an outbreak of hepatitis E were used to compare the accuracy of hepatitis E virus RNA amplification by real-time reverse transcription-PCR (RT-PCR) for sera and dried blood spots (concordance of 90.6%). Biological profiles (RT-PCR and serology) of asymptomatic individuals were also analyzed.

Platform for Automated Real-Time High Performance Analytics on Medical Image Data.

Science.gov (United States)

Allen, William J; Gabr, Refaat E; Tefera, Getaneh B; Pednekar, Amol S; Vaughn, Matthew W; Narayana, Ponnada A

2018-03-01

Biomedical data are quickly growing in volume and in variety, providing clinicians an opportunity for better clinical decision support. Here, we demonstrate a robust platform that uses software automation and high performance computing (HPC) resources to achieve real-time analytics of clinical data, specifically magnetic resonance imaging (MRI) data. We used the Agave application programming interface to facilitate communication, data transfer, and job control between an MRI scanner and an off-site HPC resource. In this use case, Agave executed the graphical pipeline tool GRAphical Pipeline Environment (GRAPE) to perform automated, real-time, quantitative analysis of MRI scans. Same-session image processing will open the door for adaptive scanning and real-time quality control, potentially accelerating the discovery of pathologies and minimizing patient callbacks. We envision this platform can be adapted to other medical instruments, HPC resources, and analytics tools.

Development and evaluation of a real-time one step Reverse-Transcriptase PCR for quantitation of Chandipura Virus

Directory of Open Access Journals (Sweden)

Tandale Babasaheb V

2008-12-01

Full Text Available Abstract Background Chandipura virus (CHPV, a member of family Rhabdoviridae was attributed to an explosive outbreak of acute encephalitis in children in Andhra Pradesh, India in 2003 and a small outbreak among tribal children from Gujarat, Western India in 2004. The case-fatality rate ranged from 55–75%. Considering the rapid progression of the disease and high mortality, a highly sensitive method for quantifying CHPV RNA by real-time one step reverse transcriptase PCR (real-time one step RT-PCR using TaqMan technology was developed for rapid diagnosis. Methods Primers and probe for P gene were designed and used to standardize real-time one step RT-PCR assay for CHPV RNA quantitation. Standard RNA was prepared by PCR amplification, TA cloning and run off transcription. The optimized real-time one step RT-PCR assay was compared with the diagnostic nested RT-PCR and different virus isolation systems [in vivo (mice in ovo (eggs, in vitro (Vero E6, PS, RD and Sand fly cell line] for the detection of CHPV. Sensitivity and specificity of real-time one step RT-PCR assay was evaluated with diagnostic nested RT-PCR, which is considered as a gold standard. Results Real-time one step RT-PCR was optimized using in vitro transcribed (IVT RNA. Standard curve showed linear relationship for wide range of 102-1010 (r2 = 0.99 with maximum Coefficient of variation (CV = 5.91% for IVT RNA. The newly developed real-time RT-PCR was at par with nested RT-PCR in sensitivity and superior to cell lines and other living systems (embryonated eggs and infant mice used for the isolation of the virus. Detection limit of real-time one step RT-PCR and nested RT-PCR was found to be 1.2 × 100 PFU/ml. RD cells, sand fly cells, infant mice, and embryonated eggs showed almost equal sensitivity (1.2 × 102 PFU/ml. Vero and PS cell-lines (1.2 × 103 PFU/ml were least sensitive to CHPV infection. Specificity of the assay was found to be 100% when RNA from other viruses or healthy

Performance evaluation of real time radiographic systems

International Nuclear Information System (INIS)

Venkatraman, B.; Saravanan, S.; Jayakumar, T.; Kalyanasundaram, P.; Baldev Raj

1996-01-01

The Real Time Radiography (RTR) system can be studied completely by knowing the modulation transfer function (MTF) of the whole system. The MTF curve is a special form of contrast/detail-size diagram in which the image contrast is plotted against the spatial frequency of a test object measured in line-pairs per millimetre (lp/mm). MTF curves are widely used to measure the characteristics of optical equipment, particularly for assessing the contribution of individual items in a complex imaging transfer system. Codes of practice indicate that the image intensifier systems should be checked periodically to assess its performance through the use of MTF curves and step wedges for contrast ratio. Authors, instead, suggest the use of performance curves which are simple to obtain and can be easily interpreted by radiographers. (author)

Towards cycle-accurate performance predictions for real-time embedded systems

NARCIS (Netherlands)

Triantafyllidis, K.; Bondarev, E.; With, de P.H.N.; Arabnia, H.R.; Deligiannidis, L.; Jandieri, G.

2013-01-01

In this paper we present a model-based performance analysis method for component-based real-time systems, featuring cycle-accurate predictions of latencies and enhanced system robustness. The method incorporates the following phases: (a) instruction-level profiling of SW components, (b) modeling the

A sensitive, reproducible, and economic real-time reverse transcription PCR detecting avian metapneumovirus subtypes A and B.

Science.gov (United States)

Franzo, G; Drigo, M; Lupini, C; Catelli, E; Laconi, A; Listorti, V; Bonci, M; Naylor, C J; Martini, M; Cecchinato, M

2014-06-01

Use of real-time PCR is increasing in the diagnosis of infectious disease due to its sensitivity, specificity, and speed of detection. These characteristics make it particularly suited for the diagnosis of viral infections, like avian metapneumovirus (AMPV), for which effective control benefits from continuously updated knowledge of the epidemiological situation. Other real-time reverse transcription (RT)-PCRs have been published based on highly specific fluorescent dye-labeled probes, but they have high initial cost, complex validation, and a marked susceptibility to the genetic variability of their target sequence. With this in mind, we developed and validated a SYBR Green I-based quantitative RT-PCR for the detection of the two most prevalent AMPV subtypes (i.e., subtypes A and B). The assay demonstrated an analytical sensitivity comparable with that of a previously published real-time RT-PCR and the ability to detect RNA equivalent to approximately 0.5 infectious doses for both A and B subtypes. The high efficiency and linearity between viral titer and crossing point displayed for both subtypes make it suited for viral quantification. Optimization of reaction conditions and the implementation of melting curve analysis guaranteed the high specificity of the assay. The stable melting temperature difference between the two subtypes indicated the possibility of subtyping through melting temperature analysis. These characteristics make our assay a sensitive, specific, and rapid tool, enabling contemporaneous detection, quantification, and discrimination of AMPV subtype A and B.

Memory controllers for high-performance and real-time MPSoCs : requirements, architectures, and future trends

NARCIS (Netherlands)

Akesson, K.B.; Huang, Po-Chun; Clermidy, F.; Dutoit, D.; Goossens, K.G.W.; Chang, Yuan-Hao; Kuo, Tei-Wei; Vivet, P.; Wingard, D.

2011-01-01

Designing memory controllers for complex real-time and high-performance multi-processor systems-on-chip is challenging, since sufficient capacity and (real-time) performance must be provided in a reliable manner at low cost and with low power consumption. This special session contains four

Time reversal imaging, Inverse problems and Adjoint Tomography}

Science.gov (United States)

Montagner, J.; Larmat, C. S.; Capdeville, Y.; Kawakatsu, H.; Fink, M.

2010-12-01

With the increasing power of computers and numerical techniques (such as spectral element methods), it is possible to address a new class of seismological problems. The propagation of seismic waves in heterogeneous media is simulated more and more accurately and new applications developed, in particular time reversal methods and adjoint tomography in the three-dimensional Earth. Since the pioneering work of J. Claerbout, theorized by A. Tarantola, many similarities were found between time-reversal methods, cross-correlations techniques, inverse problems and adjoint tomography. By using normal mode theory, we generalize the scalar approach of Draeger and Fink (1999) and Lobkis and Weaver (2001) to the 3D- elastic Earth, for theoretically understanding time-reversal method on global scale. It is shown how to relate time-reversal methods on one hand, with auto-correlations of seismograms for source imaging and on the other hand, with cross-correlations between receivers for structural imaging and retrieving Green function. Time-reversal methods were successfully applied in the past to acoustic waves in many fields such as medical imaging, underwater acoustics, non destructive testing and to seismic waves in seismology for earthquake imaging. In the case of source imaging, time reversal techniques make it possible an automatic location in time and space as well as the retrieval of focal mechanism of earthquakes or unknown environmental sources . We present here some applications at the global scale of these techniques on synthetic tests and on real data, such as Sumatra-Andaman (Dec. 2004), Haiti (Jan. 2010), as well as glacial earthquakes and seismic hum.

Development of a pan-Simbu real-time reverse transcriptase PCR for the detection of Simbu serogroup viruses and comparison with SBV diagnostic PCR systems.

Science.gov (United States)

Fischer, Melina; Schirrmeier, Horst; Wernike, Kerstin; Wegelt, Anne; Beer, Martin; Hoffmann, Bernd

2013-11-05

Schmallenberg virus (SBV), a novel orthobunyavirus of the Simbu serogroup, was first identified in October 2011 in dairy cattle in Germany, where it caused fever, diarrhea and a drop in milk yield. Since then, SBV additionally has been detected in adult sheep and goats. Although symptoms of acute infection were not observed, infection during a vulnerable phase of pregnancy caused congenital malformations and stillbirths. In view of the current situation and the possible emergence of further Simbu serogroup members, a pan-Simbu real-time reverse transcriptase (RT) PCR system for the reliable detection of Simbu serogroup viruses should be developed. In this study a pan-Simbu real-time RT-PCR system was established and compared to several SBV real-time RT-PCR assays. All PCR-systems were tested using a panel of different Simbu serogroup viruses as well as several field samples from diseased cattle, sheep and goats originating from all over Germany. Several pan-Simbu real-time RT-PCR products were sequenced via Sanger sequencing. Furthermore, in silico analyses were performed to investigate suitability for the detection of further orthobunyaviruses. All tested members of the Simbu serogroup (n = 14) as well as most of the field samples were successfully detected by the pan-Simbu real-time RT-PCR system. The comparison of this intercalating dye assay with different TaqMan probe-based assays developed for SBV diagnostics confirmed the functionality of the pan-Simbu assay for screening purposes. However, the SBV-TaqMan-assay SBV-S3 delivered the highest analytical sensitivity of less than ten copies per reaction for duplex systems including an internal control. In addition, for confirmation of SBV-genome detection the highly specific SBV-M1 assay was established. The pan-Simbu real-time RT-PCR system was able to detect all tested members of the Simbu serogroup, most of the SBV field samples as well as three tested Bunyamwera serogroup viruses with a suitable

Performances and recent evolutions of EMSC Real Time Information services

Science.gov (United States)

Mazet-Roux, G.; Godey, S.; Bossu, R.

2009-04-01

The EMSC (http://www.emsc-csem.org) operates Real Time Earthquake Information services for the public and the scientific community which aim at providing rapid and reliable information on the seismic-ity of the Euro-Mediterranean region and on significant earthquakes worldwide. These services are based on parametric data rapidly provided by 66 seismological networks which are automatically merged and processed at EMSC. A web page which is updated every minute displays a list and a map of the latest earthquakes as well as additional information like location maps, moment tensors solutions or past regional seismicity. Since 2004, the performances and the popularity of these services have dramatically increased. The number of messages received from the contributors and the number of published events have been multiplied by 2 since 2004 and by 1.6 since 2005 respectively. The web traffic and the numbers of users of the Earthquake Notification Service (ENS) have been multiplied by 15 and 7 respectively. In terms of performances of the ENS, the median dissemination time for Euro-Med events is minutes in 2008. In order to further improve its performances and especially the speed and robustness of the reception of real time data, EMSC has recently implemented a software named QWIDS (Quake Watch Information Distribution System) which provides a quick and robust data exchange system through permanent TCP connections. At the difference with emails that can sometimes be delayed or lost, QWIDS is an actual real time communication system that ensures the data delivery. In terms of hardware, EMSC imple-mented a high availability, dynamic load balancing, redundant and scalable web servers infrastructure, composed of two SUN T2000 and one F5 BIG-IP switch. This will allow coping with constantly increas-ing web traffic and the occurrence of huge peaks of traffic after widely felt earthquakes.

FPGA cluster for high-performance AO real-time control system

Science.gov (United States)

Geng, Deli; Goodsell, Stephen J.; Basden, Alastair G.; Dipper, Nigel A.; Myers, Richard M.; Saunter, Chris D.

2006-06-01

Whilst the high throughput and low latency requirements for the next generation AO real-time control systems have posed a significant challenge to von Neumann architecture processor systems, the Field Programmable Gate Array (FPGA) has emerged as a long term solution with high performance on throughput and excellent predictability on latency. Moreover, FPGA devices have highly capable programmable interfacing, which lead to more highly integrated system. Nevertheless, a single FPGA is still not enough: multiple FPGA devices need to be clustered to perform the required subaperture processing and the reconstruction computation. In an AO real-time control system, the memory bandwidth is often the bottleneck of the system, simply because a vast amount of supporting data, e.g. pixel calibration maps and the reconstruction matrix, need to be accessed within a short period. The cluster, as a general computing architecture, has excellent scalability in processing throughput, memory bandwidth, memory capacity, and communication bandwidth. Problems, such as task distribution, node communication, system verification, are discussed.

Development of a real-time RT-PCR and Reverse Line probe Hybridisation assay for the routine detection and genotyping of Noroviruses in Ireland.

LENUS (Irish Health Repository)

Menton, John F

2007-01-01

BACKGROUND: Noroviruses are the most common cause of non-bacterial gastroenteritis. Improved detection methods have seen a large increase in the number of human NoV genotypes in the last ten years. The objective of this study was to develop a fast method to detect, quantify and genotype positive NoV samples from Irish hospitals. RESULTS: A real-time RT-PCR assay and a Reverse Line Blot Hybridisation assay were developed based on the ORF1-ORF2 region. The sensitivity and reactivity of the two assays used was validated using a reference stool panel containing 14 NoV genotypes. The assays were then used to investigate two outbreaks of gastroenteritis in two Irish hospitals. 56 samples were screened for NoV using a real-time RT-PCR assay and 26 samples were found to be positive. Genotyping of these positive samples found that all positives belonged to the GII\\/4 variant of NoV. CONCLUSION: The combination of the Real-time assay and the reverse line blot hybridisation assay provided a fast and accurate method to investigate a NoV associated outbreak. It was concluded that the predominant genotype circulating in these Irish hospitals was GII\\/4 which has been associated with the majority of NoV outbreaks worldwide. The assays developed in this study are useful tools for investigating NoV infection.

Remote Whispering Applying Time Reversal

Energy Technology Data Exchange (ETDEWEB)

Anderson, Brian Eric [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2015-07-16

The purpose of this project was to explore the use of time reversal technologies as a means for communication to a targeted individual or location. The idea is to have the privacy of whispering in one’s ear, but to do this remotely from loudspeakers not located near the target. Applications of this work include communicating with hostages and survivors in rescue operations, communicating imaging and operational conditions in deep drilling operations, monitoring storage of spent nuclear fuel in storage casks without wires, or clandestine activities requiring signaling between specific points. This technology provides a solution in any application where wires and radio communications are not possible or not desired. It also may be configured to self calibrate on a regular basis to adjust for changing conditions. These communications allow two people to converse with one another in real time, converse in an inaudible frequency range or medium (i.e. using ultrasonic frequencies and/or sending vibrations through a structure), or send information for a system to interpret (even allowing remote control of a system using sound). The time reversal process allows one to focus energy to a specific location in space and to send a clean transmission of a selected signal only to that location. In order for the time reversal process to work, a calibration signal must be obtained. This signal may be obtained experimentally using an impulsive sound, a known chirp signal, or other known signals. It may also be determined from a numerical model of a known environment in which the focusing is desired or from passive listening over time to ambient noise.

Performance Comparison of EPICS IOC and MARTe in a Hard Real-Time Control Application

Science.gov (United States)

Barbalace, Antonio; Manduchi, Gabriele; Neto, A.; De Tommasi, G.; Sartori, F.; Valcarcel, D. F.

2011-12-01

EPICS is used worldwide mostly for controlling accelerators and large experimental physics facilities. Although EPICS is well fit for the design and development of automation systems, which are typically VME or PLC-based systems, and for soft real-time systems, it may present several drawbacks when used to develop hard real-time systems/applications especially when general purpose operating systems as plain Linux are chosen. This is in particular true in fusion research devices typically employing several hard real-time systems, such as the magnetic control systems, that may require strict determinism, and high performance in terms of jitter and latency. Serious deterioration of important plasma parameters may happen otherwise, possibly leading to an abrupt termination of the plasma discharge. The MARTe framework has been recently developed to fulfill the demanding requirements for such real-time systems that are alike to run on general purpose operating systems, possibly integrated with the low-latency real-time preemption patches. MARTe has been adopted to develop a number of real-time systems in different Tokamaks. In this paper, we first summarize differences and similarities between EPICS IOC and MARTe. Then we report on a set of performance measurements executed on an x86 64 bit multicore machine running Linux with an IO control algorithm implemented in an EPICS IOC and in MARTe.

Dynamic, in vivo, real-time detection of retinal oxidative status in a model of elevated intraocular pressure using a novel, reversibly responsive, profluorescent nitroxide probe.

Science.gov (United States)

Rayner, Cassie L; Gole, Glen A; Bottle, Steven E; Barnett, Nigel L

2014-12-01

Changes to the redox status of biological systems have been implicated in the pathogenesis of a wide variety of disorders including cancer, Ischemia-reperfusion (I/R) injury and neurodegeneration. In times of metabolic stress e.g. ischaemia/reperfusion, reactive oxygen species (ROS) production overwhelms the intrinsic antioxidant capacity of the cell, damaging vital cellular components. The ability to quantify ROS changes in vivo, is therefore essential to understanding their biological role. Here we evaluate the suitability of a novel reversible profluorescent probe containing a redox-sensitive nitroxide moiety (methyl ester tetraethylrhodamine nitroxide, ME-TRN), as an in vivo, real-time reporter of retinal oxidative status. The reversible nature of the probe's response offers the unique advantage of being able to monitor redox changes in both oxidizing and reducing directions in real time. After intravitreal administration of the ME-TRN probe, we induced ROS production in rat retina using an established model of complete, acute retinal ischaemia followed by reperfusion. After restoration of blood flow, retinas were imaged using a Micron III rodent fundus fluorescence imaging system, to quantify the redox-response of the probe. Fluorescent intensity declined during the first 60 min of reperfusion. The ROS-induced change in probe fluorescence was ameliorated with the retinal antioxidant, lutein. Fluorescence intensity in non-Ischemia eyes did not change significantly. This new probe and imaging technology provide a reversible and real-time response to oxidative changes and may allow the in vivo testing of antioxidant therapies of potential benefit to a range of diseases linked to oxidative stress. Copyright © 2014 Elsevier Ltd. All rights reserved.

Use of high performance networks and supercomputers for real-time flight simulation

Science.gov (United States)

Cleveland, Jeff I., II

1993-01-01

In order to meet the stringent time-critical requirements for real-time man-in-the-loop flight simulation, computer processing operations must be consistent in processing time and be completed in as short a time as possible. These operations include simulation mathematical model computation and data input/output to the simulators. In 1986, in response to increased demands for flight simulation performance, NASA's Langley Research Center (LaRC), working with the contractor, developed extensions to the Computer Automated Measurement and Control (CAMAC) technology which resulted in a factor of ten increase in the effective bandwidth and reduced latency of modules necessary for simulator communication. This technology extension is being used by more than 80 leading technological developers in the United States, Canada, and Europe. Included among the commercial applications are nuclear process control, power grid analysis, process monitoring, real-time simulation, and radar data acquisition. Personnel at LaRC are completing the development of the use of supercomputers for mathematical model computation to support real-time flight simulation. This includes the development of a real-time operating system and development of specialized software and hardware for the simulator network. This paper describes the data acquisition technology and the development of supercomputing for flight simulation.

A Method to Predict Compressor Stall in the TF34-100 Turbofan Engine Utilizing Real-Time Performance Data

Science.gov (United States)

2015-06-01

A METHOD TO PREDICT COMPRESSOR STALL IN THE TF34-100 TURBOFAN ENGINE UTILIZING REAL-TIME PERFORMANCE...THE TF34-100 TURBOFAN ENGINE UTILIZING REAL-TIME PERFORMANCE DATA THESIS Presented to the Faculty Department of Systems Engineering and...036 A METHOD TO PREDICT COMPRESSOR STALL IN THE TF34-100 TURBOFAN ENGINE UTILIZING REAL-TIME PERFORMANCE DATA Shuxiang ‘Albert’ Li, BS

A novel duplex real-time reverse transcriptase-polymerase chain reaction assay for the detection of hepatitis C viral RNA with armored RNA as internal control

Directory of Open Access Journals (Sweden)

Meng Shuang

2010-06-01

Full Text Available Abstract Background The hepatitis C virus (HCV genome is extremely heterogeneous. Several HCV infections can not be detected using currently available commercial assays, probably because of mismatches between the template and primers/probes. By aligning the HCV sequences, we developed a duplex real-time reverse transcriptase-polymerase chain reaction (RT-PCR assay using 2 sets of primers/probes and a specific armored RNA as internal control. The 2 detection probes were labelled with the same fluorophore, namely, 6-carboxyfluorescein (FAM, at the 5' end; these probes could mutually combine, improving the power of the test. Results The limit of detection of the duplex primer/probe assay was 38.99 IU/ml. The sensitivity of the assay improved significantly, while the specificity was not affected. All HCV genotypes in the HCV RNA Genotype Panel for Nucleic Acid Amplification Techniques could be detected. In the testing of 109 serum samples, the performance of the duplex real-time RT-PCR assay was identical to that of the COBAS AmpliPrep (CAP/COBAS TaqMan (CTM assay and superior to 2 commercial HCV assay kits. Conclusions The duplex real-time RT-PCR assay is an efficient and effective viral assay. It is comparable with the CAP/CTM assay with regard to the power of the test and is appropriate for blood-donor screening and laboratory diagnosis of HCV infection.

Porcine reproductive and respiratory syndrome virus: Interlaboratory ring trial to evaluate real-time reverse transcription polymerase chain reaction detection methods

DEFF Research Database (Denmark)

Wernike, Kerstin; Bonilauri, Paolo; Dauber, Malte

2012-01-01

To compare the real-time reverse transcription quantitative polymerase chain reaction (RT-qPCR) assays used for the diagnosis of Porcine reproductive and respiratory syndrome virus (PRRSV), a Europe-wide interlaboratory ring trial was conducted. A variety of PRRSV strains including North American...... (NA) and European (EU) genotype isolates were analyzed by the participants. Great differences regarding qualitative diagnostics as well as analytical sensitivity were observed between the individual RT-qPCR systems, especially when investigating strains from the EU genotype. None of the assays...

Use of a novel virus inactivation method for a multicenter avian influenza real-time reverse transcriptase-polymerase chain reaction proficiency study.

Science.gov (United States)

Spackman, Erica; Suarez, David L

2005-01-01

Proficiency assessments are important elements in quality control for diagnostic laboratories. Traditionally, proficiency testing for polymerase chain reaction (PCR)-based assays has involved the use of clinical samples, samples "spiked" with live agents or DNA plasmids. Because of government regulations and biosecurity concerns, distribution of live high-consequence pathogens of livestock and poultry, such as avian influenza, is not possible, and DNA plasmids are not technically suitable for evaluating RNA virus detection. Therefore, a proficiency testing panel using whole avian influenza in a diluent containing a phenolic disinfectant that inactivates the virus while preserving the RNA for at least 8 weeks at -70 C was developed and used in a multicenter proficiency assessment for a type A influenza real-time reverse transcriptase (RT)-PCR test. The test, which was highly standardized, except for variation in the real-time RT-PCR equipment used, was shown to be highly reproducible by proficiency testing in 12 laboratories in the United States, Canada, and Hong Kong. Variation in cycle threshold values among 35 data sets and 490 samples was minimal (CV = 5.19%), and sample identifications were highly accurate (96.7% correct identifications) regardless of real-time PCR instrumentation.

Performance analysis of an acoustic time reversal system in dynamic and random oceanic environments

Science.gov (United States)

Khosla, Sunny Rajendra

This dissertation provides a theoretical framework along with specific performance predictions for an acoustic time reversal system in shallow oceanic environments. Acoustic time-reversal is a robust means of retrofocusing acoustic energy, in both time and space, to the original sound-source location without any information about the acoustic environment in which it is deployed. The effect of three performance limiting oceanic complexities addressed, include (i)ambient noise field, (ii)reflection and volume scattering from a deterministic soliton internal wave traveling on the thermocline between two water masses, and (iii)volume scattering from a random superposition of linear internal waves convecting a gradient in the sound speed profile. The performance analysis establishes acoustic time reversal to be a promising technology for a two-way communication system in an oceanic medium. For an omni-directional noisy environment a general formulation for the probability of retrofocusing is developed that includes the effect of the medium, accounts for the system hardware and the acoustic parameters. Monte-Carlo simulations in both, a free-space environment and a shallow-ocean sound-channel environment compare well with theory. A 41 element TRA spanning a shallow water depth of 60 m is predicted to return a 70% focal probability at -15 dB SNR for a source to array range of 6 km. Preliminary research with broadband signals suggest that they should outperform narrowband response in both free space and sound channel environments. The impact of the nonlinear solitary waves is addressed using a two-path Green's function to treat the presence of a flat thermocline, and the single scattering Born approximation to address scattering from the soliton internal wave. It is predicted that a stationary soliton located along ray turning paths between the source and the TRA can lead to both enhanced and degraded focal performance. Based on extension of previous research in wave

Detection of Tumor Cell-Specific mRNA in the Peripheral Blood of Patients with Breast Cancer — Evaluation of Several Markers with Real-Time Reverse Transcription-PCR

Directory of Open Access Journals (Sweden)

Ulrich Andergassen

2013-01-01

Full Text Available It is widely known that cells from epithelial tumors, e.g., breast cancer, detach from their primary tissue and enter blood circulation. We show that the presence of circulating tumor cells (CTCs in samples of patients with primary and metastatic breast cancer can be detected with an array of selected tumor-marker-genes by reverse transcription real-time PCR. The focus of the presented work is on detecting differences in gene expression between healthy individuals and adjuvant and metastatic breast cancer patients, not an accurate quantification of these differences. Therefore, total RNA was isolated from blood samples of healthy donors and patients with primary or metastatic breast cancer after enrichment of mononuclear cells by density gradient centrifugation. After reverse transcription real-time PCR was carried out with a set of marker genes (BCSP, CK8, Her2, MGL, CK18, CK19. B2M and GAPDH were used as reference genes. Blood samples from patients with metastatic disease revealed increased cytokine gene levels in comparison to normal blood samples. Detection of a single gene was not sufficient to detect CTCs by reverse transcription real-time PCR. Markers used here were selected based on a recent study detecting cancer cells on different protein levels. The combination of such a marker array leads to higher and more specific discovery rates, predominantly in metastatic patients. Identification of CTCs by PCR methods may lead to better diagnosis and prognosis and could help to choose an adequate therapy.

Performance Evaluation of the Real-Q Cytomegalovirus (CMV) Quantification Kit Using Two Real-Time PCR Systems for Quantifying CMV DNA in Whole Blood.

Science.gov (United States)

Park, Jong Eun; Kim, Ji Youn; Yun, Sun Ae; Lee, Myoung Keun; Huh, Hee Jae; Kim, Jong Won; Ki, Chang Seok

2016-11-01

Standardized cytomegalovirus (CMV) DNA quantification is important for managing CMV disease. We evaluated the performance of the Real-Q CMV Quantification Kit (Real-Q assay; BioSewoom, Korea) using whole blood (WB), with nucleic acid extraction using MagNA Pure 96 (Roche Diagnostics, Germany). Real-time PCR was performed on two platforms: the 7500 Fast real-time PCR (7500 Fast; Applied Biosystems, USA) and CFX96 real-time PCR detection (CFX96; Bio-Rad, USA) systems. The WHO international standard, diluted with CMV-negative WB, was used to validate the analytical performance. We used 90 WB clinical samples for comparison with the artus CMV RG PCR kit (artus assay; Qiagen, Germany). Limits of detections (LODs) in 7500 Fast and CFX96 were 367 and 479 IU/mL, respectively. The assay was linear from the LOD to 10⁶ IU/mL (R² ≥0.9886). The conversion factors from copies to IU in 7500 Fast and CFX96 were 0.95 and 1.06, respectively. Compared with the artus assay, for values 1,000 copies/mL, 73.3% and 80.6% of samples in 7500 Fast and CFX96, respectively, had real-time PCR platforms.

Testing the causality of Hawkes processes with time reversal

Science.gov (United States)

Cordi, Marcus; Challet, Damien; Muni Toke, Ioane

2018-03-01

We show that univariate and symmetric multivariate Hawkes processes are only weakly causal: the true log-likelihoods of real and reversed event time vectors are almost equal, thus parameter estimation via maximum likelihood only weakly depends on the direction of the arrow of time. In ideal (synthetic) conditions, tests of goodness of parametric fit unambiguously reject backward event times, which implies that inferring kernels from time-symmetric quantities, such as the autocovariance of the event rate, only rarely produce statistically significant fits. Finally, we find that fitting financial data with many-parameter kernels may yield significant fits for both arrows of time for the same event time vector, sometimes favouring the backward time direction. This goes to show that a significant fit of Hawkes processes to real data with flexible kernels does not imply a definite arrow of time unless one tests it.

Memory controllers for real-time embedded systems predictable and composable real-time systems

CERN Document Server

Akesson, Benny

2012-01-01

  Verification of real-time requirements in systems-on-chip becomes more complex as more applications are integrated. Predictable and composable systems can manage the increasing complexity using formal verification and simulation.  This book explains the concepts of predictability and composability and shows how to apply them to the design and analysis of a memory controller, which is a key component in any real-time system. This book is generally intended for readers interested in Systems-on-Chips with real-time applications.   It is especially well-suited for readers looking to use SDRAM memories in systems with hard or firm real-time requirements. There is a strong focus on real-time concepts, such as predictability and composability, as well as a brief discussion about memory controller architectures for high-performance computing. Readers will learn step-by-step how to go from an unpredictable SDRAM memory, offering highly variable bandwidth and latency, to a predictable and composable shared memory...

Performance Evaluation of RIPng, EIGRPv6 and OSPFv3 for Real Time Applications

Directory of Open Access Journals (Sweden)

Sama Salam Samaan

2018-01-01

Full Text Available In this modern Internet era and the transition to IPv6, routing protocols must adjust to assist this transformation. RIPng, EIGRPv6 and OSPFv3 are the dominant IPv6 IGRP (Interior Gateway Routing Protocols. Selecting the best routing protocol among the available is a critical task, which depends upon the network requirement and performance parameters of different real time applications. The primary motivation of this paper is to estimate the performance of these protocols in real time applications. The evaluation is based on a number of criteria including: network convergence duration, Http Page Response Time, DB Query Response Time, IPv6 traffic dropped, video packet delay variation and video packet end to end delay. After examining the simulation results, a conclusion will be extracted to reveal the findings of which protocol performs the best upon implementation within a IPv6 WAN. OPNET modeler simulator is used to evaluate the accomplishment of these protocols. To get the results, three scenarios are designed, one for each protocol.

Rapid Genome Detection of Schmallenberg Virus and Bovine Viral Diarrhea Virus by Use of Isothermal Amplification Methods and High-Speed Real-Time Reverse Transcriptase PCR

OpenAIRE

Aebischer, Andrea; Wernike, Kerstin; Hoffmann, Bernd; Beer, Martin

2014-01-01

Over the past few years, there has been an increasing demand for rapid and simple diagnostic tools that can be applied outside centralized laboratories by using transportable devices. In veterinary medicine, such mobile test systems would circumvent barriers associated with the transportation of samples and significantly reduce the time to diagnose important infectious animal diseases. Among a wide range of available technologies, high-speed real-time reverse transcriptase quantitative PCR (R...

Reversal of the lattice structure in SrCoOx epitaxial thin films studied by real-time optical spectroscopy and first-principles calculations

OpenAIRE

Choi, Woo Seok; Jeen, Hyoungjeen; Lee, Jun Hee; Seo, S. S. Ambrose; Cooper, Valentino R.; Rabe, Karin M.; Lee, Ho Nyung

2013-01-01

Using real-time spectroscopic ellipsometry, we directly observed a reversible lattice and electronic structure evolution in SrCoOx (x = 2.5 - 3) epitaxial thin films. Drastically different electronic ground states, which are extremely susceptible to the oxygen content x, are found in the two topotactic phases, i.e. the brownmillerite SrCoO2.5 and the perovskite SrCoO3. First principles calculations confirmed substantial differences in the electronic structure, including a metal-insulator tran...

Real-Time Facial Segmentation and Performance Capture from RGB Input

OpenAIRE

Saito, Shunsuke; Li, Tianye; Li, Hao

2016-01-01

We introduce the concept of unconstrained real-time 3D facial performance capture through explicit semantic segmentation in the RGB input. To ensure robustness, cutting edge supervised learning approaches rely on large training datasets of face images captured in the wild. While impressive tracking quality has been demonstrated for faces that are largely visible, any occlusion due to hair, accessories, or hand-to-face gestures would result in significant visual artifacts and loss of tracking ...

High performance embedded system for real-time pattern matching

Energy Technology Data Exchange (ETDEWEB)

Sotiropoulou, C.-L., E-mail: c.sotiropoulou@cern.ch [University of Pisa, Largo B. Pontecorvo 3, 56127 Pisa (Italy); INFN-Pisa Section, Largo B. Pontecorvo 3, 56127 Pisa (Italy); Luciano, P. [University of Cassino and Southern Lazio, Gaetano di Biasio 43, Cassino 03043 (Italy); INFN-Pisa Section, Largo B. Pontecorvo 3, 56127 Pisa (Italy); Gkaitatzis, S. [Aristotle University of Thessaloniki, 54124 Thessaloniki (Greece); Citraro, S. [University of Pisa, Largo B. Pontecorvo 3, 56127 Pisa (Italy); INFN-Pisa Section, Largo B. Pontecorvo 3, 56127 Pisa (Italy); Giannetti, P. [INFN-Pisa Section, Largo B. Pontecorvo 3, 56127 Pisa (Italy); Dell' Orso, M. [University of Pisa, Largo B. Pontecorvo 3, 56127 Pisa (Italy); INFN-Pisa Section, Largo B. Pontecorvo 3, 56127 Pisa (Italy)

2017-02-11

In this paper we present an innovative and high performance embedded system for real-time pattern matching. This system is based on the evolution of hardware and algorithms developed for the field of High Energy Physics and more specifically for the execution of extremely fast pattern matching for tracking of particles produced by proton–proton collisions in hadron collider experiments. A miniaturized version of this complex system is being developed for pattern matching in generic image processing applications. The system works as a contour identifier able to extract the salient features of an image. It is based on the principles of cognitive image processing, which means that it executes fast pattern matching and data reduction mimicking the operation of the human brain. The pattern matching can be executed by a custom designed Associative Memory chip. The reference patterns are chosen by a complex training algorithm implemented on an FPGA device. Post processing algorithms (e.g. pixel clustering) are also implemented on the FPGA. The pattern matching can be executed on a 2D or 3D space, on black and white or grayscale images, depending on the application and thus increasing exponentially the processing requirements of the system. We present the firmware implementation of the training and pattern matching algorithm, performance and results on a latest generation Xilinx Kintex Ultrascale FPGA device. - Highlights: • A high performance embedded system for real-time pattern matching is proposed. • It is based on a system developed for High Energy Physics experiment triggers. • It mimics the operation of the human brain (cognitive image processing). • The process can be executed on 2D and 3D, black and white or grayscale images. • The implementation uses FPGAs and custom designed associative memory (AM) chips.

High performance embedded system for real-time pattern matching

International Nuclear Information System (INIS)

Sotiropoulou, C.-L.; Luciano, P.; Gkaitatzis, S.; Citraro, S.; Giannetti, P.; Dell'Orso, M.

2017-01-01

In this paper we present an innovative and high performance embedded system for real-time pattern matching. This system is based on the evolution of hardware and algorithms developed for the field of High Energy Physics and more specifically for the execution of extremely fast pattern matching for tracking of particles produced by proton–proton collisions in hadron collider experiments. A miniaturized version of this complex system is being developed for pattern matching in generic image processing applications. The system works as a contour identifier able to extract the salient features of an image. It is based on the principles of cognitive image processing, which means that it executes fast pattern matching and data reduction mimicking the operation of the human brain. The pattern matching can be executed by a custom designed Associative Memory chip. The reference patterns are chosen by a complex training algorithm implemented on an FPGA device. Post processing algorithms (e.g. pixel clustering) are also implemented on the FPGA. The pattern matching can be executed on a 2D or 3D space, on black and white or grayscale images, depending on the application and thus increasing exponentially the processing requirements of the system. We present the firmware implementation of the training and pattern matching algorithm, performance and results on a latest generation Xilinx Kintex Ultrascale FPGA device. - Highlights: • A high performance embedded system for real-time pattern matching is proposed. • It is based on a system developed for High Energy Physics experiment triggers. • It mimics the operation of the human brain (cognitive image processing). • The process can be executed on 2D and 3D, black and white or grayscale images. • The implementation uses FPGAs and custom designed associative memory (AM) chips.

Reverse time migration by Krylov subspace reduced order modeling

Science.gov (United States)

Basir, Hadi Mahdavi; Javaherian, Abdolrahim; Shomali, Zaher Hossein; Firouz-Abadi, Roohollah Dehghani; Gholamy, Shaban Ali

2018-04-01

Imaging is a key step in seismic data processing. To date, a myriad of advanced pre-stack depth migration approaches have been developed; however, reverse time migration (RTM) is still considered as the high-end imaging algorithm. The main limitations associated with the performance cost of reverse time migration are the intensive computation of the forward and backward simulations, time consumption, and memory allocation related to imaging condition. Based on the reduced order modeling, we proposed an algorithm, which can be adapted to all the aforementioned factors. Our proposed method benefit from Krylov subspaces method to compute certain mode shapes of the velocity model computed by as an orthogonal base of reduced order modeling. Reverse time migration by reduced order modeling is helpful concerning the highly parallel computation and strongly reduces the memory requirement of reverse time migration. The synthetic model results showed that suggested method can decrease the computational costs of reverse time migration by several orders of magnitudes, compared with reverse time migration by finite element method.

Performance Evaluation of Components Using a Granularity-based Interface Between Real-Time Calculus and Timed Automata

Directory of Open Access Journals (Sweden)

Karine Altisen

2010-06-01

Full Text Available To analyze complex and heterogeneous real-time embedded systems, recent works have proposed interface techniques between real-time calculus (RTC and timed automata (TA, in order to take advantage of the strengths of each technique for analyzing various components. But the time to analyze a state-based component modeled by TA may be prohibitively high, due to the state space explosion problem. In this paper, we propose a framework of granularity-based interfacing to speed up the analysis of a TA modeled component. First, we abstract fine models to work with event streams at coarse granularity. We perform analysis of the component at multiple coarse granularities and then based on RTC theory, we derive lower and upper bounds on arrival patterns of the fine output streams using the causality closure algorithm. Our framework can help to achieve tradeoffs between precision and analysis time.

Performances of the New Real Time Tsunami Detection Algorithm applied to tide gauges data

Science.gov (United States)

Chierici, F.; Embriaco, D.; Morucci, S.

2017-12-01

Real-time tsunami detection algorithms play a key role in any Tsunami Early Warning System. We have developed a new algorithm for tsunami detection (TDA) based on the real-time tide removal and real-time band-pass filtering of seabed pressure time series acquired by Bottom Pressure Recorders. The TDA algorithm greatly increases the tsunami detection probability, shortens the detection delay and enhances detection reliability with respect to the most widely used tsunami detection algorithm, while containing the computational cost. The algorithm is designed to be used also in autonomous early warning systems with a set of input parameters and procedures which can be reconfigured in real time. We have also developed a methodology based on Monte Carlo simulations to test the tsunami detection algorithms. The algorithm performance is estimated by defining and evaluating statistical parameters, namely the detection probability, the detection delay, which are functions of the tsunami amplitude and wavelength, and the occurring rate of false alarms. In this work we present the performance of the TDA algorithm applied to tide gauge data. We have adapted the new tsunami detection algorithm and the Monte Carlo test methodology to tide gauges. Sea level data acquired by coastal tide gauges in different locations and environmental conditions have been used in order to consider real working scenarios in the test. We also present an application of the algorithm to the tsunami event generated by Tohoku earthquake on March 11th 2011, using data recorded by several tide gauges scattered all over the Pacific area.

Real-time systems

OpenAIRE

Badr, Salah M.; Bruztman, Donald P.; Nelson, Michael L.; Byrnes, Ronald Benton

1992-01-01

This paper presents an introduction to the basic issues involved in real-time systems. Both real-time operating sys and real-time programming languages are explored. Concurrent programming and process synchronization and communication are also discussed. The real-time requirements of the Naval Postgraduate School Autonomous Under Vehicle (AUV) are then examined. Autonomous underwater vehicle (AUV), hard real-time system, real-time operating system, real-time programming language, real-time sy...

Reversal of the Lattice Structure in SrCoOx Epitaxial Thin Films Studied by Real-Time Optical Spectroscopy and First-Principles Calculations

Science.gov (United States)

Choi, Woo Seok; Jeen, Hyoungjeen; Lee, Jun Hee; Seo, S. S. Ambrose; Cooper, Valentino R.; Rabe, Karin M.; Lee, Ho Nyung

2013-08-01

Using real-time spectroscopic ellipsometry, we directly observed a reversible lattice and electronic structure evolution in SrCoOx (x=2.5-3) epitaxial thin films. Drastically different electronic ground states, which are extremely susceptible to the oxygen content x, are found in the two topotactic phases: i.e., the brownmillerite SrCoO2.5 and the perovskite SrCoO3. First-principles calculations confirmed substantial differences in the electronic structure, including a metal-insulator transition, which originate from the modification in the Co valence states and crystallographic structures. More interestingly, the two phases can be reversibly controlled by changing the ambient pressure at greatly reduced temperatures. Our finding provides an important pathway to understanding the novel oxygen-content-dependent phase transition uniquely found in multivalent transition metal oxides.

DSP-Based Focusing over Optical Fiber Using Time Reversal

DEFF Research Database (Denmark)

Piels, Molly; Porto da Silva, Edson; Estaran Tolosa, Jose Manuel

2014-01-01

A time-reversal array in multimode fiber is proposed for lossless switching using passive optical splitters. Numerical investigations are performed, and a two-transmitter array that routes a 3GBd QPSK signal through the physical layer is demonstrated experimentally.......A time-reversal array in multimode fiber is proposed for lossless switching using passive optical splitters. Numerical investigations are performed, and a two-transmitter array that routes a 3GBd QPSK signal through the physical layer is demonstrated experimentally....

Performance enhancement of various real-time image processing techniques via speculative execution

Science.gov (United States)

Younis, Mohamed F.; Sinha, Purnendu; Marlowe, Thomas J.; Stoyenko, Alexander D.

1996-03-01

In real-time image processing, an application must satisfy a set of timing constraints while ensuring the semantic correctness of the system. Because of the natural structure of digital data, pure data and task parallelism have been used extensively in real-time image processing to accelerate the handling time of image data. These types of parallelism are based on splitting the execution load performed by a single processor across multiple nodes. However, execution of all parallel threads is mandatory for correctness of the algorithm. On the other hand, speculative execution is an optimistic execution of part(s) of the program based on assumptions on program control flow or variable values. Rollback may be required if the assumptions turn out to be invalid. Speculative execution can enhance average, and sometimes worst-case, execution time. In this paper, we target various image processing techniques to investigate applicability of speculative execution. We identify opportunities for safe and profitable speculative execution in image compression, edge detection, morphological filters, and blob recognition.

Sensitivity and specificity of a real-time reverse transcriptase polymerase chain reaction detecting feline coronavirus mutations in effusion and serum/plasma of cats to diagnose feline infectious peritonitis

NARCIS (Netherlands)

Felten, Sandra; Leutenegger, Christian M.; Balzer, Hans Joerg; Pantchev, Nikola; Matiasek, Kaspar; Wess, Gerhard; Egberink, Herman|info:eu-repo/dai/nl/089740890; Hartmann, Katrin

2017-01-01

Background: Feline coronavirus (FCoV) exists as two pathotypes, and FCoV spike gene mutations are considered responsible for the pathotypic switch in feline infectious peritonitis (FIP) pathogenesis. The aim of this study was to evaluate sensitivity and specificity of a real-time reverse

Real-Time Projection-Based Augmented Reality System for Dynamic Objects in the Performing Arts

Directory of Open Access Journals (Sweden)

Jaewoon Lee

2015-02-01

Full Text Available This paper describes the case study of applying projection-based augmented reality, especially for dynamic objects in live performing shows, such as plays, dancing, or musicals. Our study aims to project imagery correctly inside the silhouettes of flexible objects, in other words, live actors or the surface of actor’s costumes; the silhouette transforms its own shape frequently. To realize this work, we implemented a special projection system based on the real-time masking technique, that is to say real-time projection-based augmented reality system for dynamic objects in performing arts. We installed the sets on a stage for live performance, and rehearsed particular scenes of a musical. In live performance, using projection-based augmented reality technology enhances technical and theatrical aspects which were not possible with existing video projection techniques. The projected images on the surfaces of actor’s costume could not only express the particular scene of a performance more effectively, but also lead the audience to an extraordinary visual experience.

Neural network evaluation of tokamak current profiles for real time control

Science.gov (United States)

Wróblewski, Dariusz

1997-02-01

Active feedback control of the current profile, requiring real-time determination of the current profile parameters, is envisioned for tokamaks operating in enhanced confinement regimes. The distribution of toroidal current in a tokamak is now routinely evaluated based on external (magnetic probes, flux loops) and internal (motional Stark effect) measurements of the poloidal magnetic field. However, the analysis involves reconstruction of magnetohydrodynamic equilibrium and is too intensive computationally to be performed in real time. In the present study, a neural network is used to provide a mapping from the magnetic measurements (internal and external) to selected parameters of the safety factor profile. The single-pass, feedforward calculation of output of a trained neural network is very fast, making this approach particularly suitable for real-time applications. The network was trained on a large set of simulated equilibrium data for the DIII-D tokamak. The database encompasses a large variety of current profiles including the hollow current profiles important for reversed central shear operation. The parameters of safety factor profile (a quantity related to the current profile through the magnetic field tilt angle) estimated by the neural network include central safety factor, q0, minimum value of q, qmin, and the location of qmin. Very good performance of the trained neural network both for simulated test data and for experimental datais demonstrated.

Neural network evaluation of tokamak current profiles for real time control

International Nuclear Information System (INIS)

Wroblewski, D.

1997-01-01

Active feedback control of the current profile, requiring real-time determination of the current profile parameters, is envisioned for tokamaks operating in enhanced confinement regimes. The distribution of toroidal current in a tokamak is now routinely evaluated based on external (magnetic probes, flux loops) and internal (motional Stark effect) measurements of the poloidal magnetic field. However, the analysis involves reconstruction of magnetohydrodynamic equilibrium and is too intensive computationally to be performed in real time. In the present study, a neural network is used to provide a mapping from the magnetic measurements (internal and external) to selected parameters of the safety factor profile. The single-pass, feedforward calculation of output of a trained neural network is very fast, making this approach particularly suitable for real-time applications. The network was trained on a large set of simulated equilibrium data for the DIII-D tokamak. The database encompasses a large variety of current profiles including the hollow current profiles important for reversed central shear operation. The parameters of safety factor profile (a quantity related to the current profile through the magnetic field tilt angle) estimated by the neural network include central safety factor, q 0 , minimum value of q, q min , and the location of q min . Very good performance of the trained neural network both for simulated test data and for experimental datais demonstrated. copyright 1997 American Institute of Physics

Manipulating motor performance and memory through real-time fMRI neurofeedback

OpenAIRE

Scharnowski, Frank; Veit, Ralf; Zopf, Regine; Studer, Petra; Bock, Simon; Diedrichsen, Jörn; Goebel, Rainer; Mathiak, Klaus; Birbaumer, Niels; Weiskopf, Nikolaus

2015-01-01

Task performance depends on ongoing brain activity which can be influenced by attention, arousal, or motivation. However, such modulating factors of cognitive efficiency are unspecific, can be difficult to control, and are not suitable to facilitate neural processing in a regionally specific manner. Here, we non-pharmacologically manipulated regionally specific brain activity using technically sophisticated real-time fMRI neurofeedback. This was accomplished by training participants to simult...

Classical swine fever virus detection: results of a real-time reverse transcription polymerase chain reaction ring trial conducted in the framework of the European network of excellence for epizootic disease diagnosis and control

DEFF Research Database (Denmark)

Hoffmann, Bernd; Blome, Sandra; Bonilauri, Paolo

2011-01-01

and specificity values. Nevertheless, some in-house systems had unspecific reactions or suboptimal sensitivity with only a single CSFV genotype. Follow-up actions involved either improvement of suboptimal assays or replacement of specific laboratory assays with the FLI protocol, with or without modifications......The current study reports on a real-time reverse transcription polymerase chain reaction (real-time RT-PCR) ring trial for the detection of Classical swine fever virus (CSFV) genomic RNA undertaken by 10 European laboratories. All laboratories were asked to use their routine in-house real-time RT...

Real-Time Performance of Mechatronic PZT Module Using Active Vibration Feedback Control.

Science.gov (United States)

Aggogeri, Francesco; Borboni, Alberto; Merlo, Angelo; Pellegrini, Nicola; Ricatto, Raffaele

2016-09-25

This paper proposes an innovative mechatronic piezo-actuated module to control vibrations in modern machine tools. Vibrations represent one of the main issues that seriously compromise the quality of the workpiece. The active vibration control (AVC) device is composed of a host part integrated with sensors and actuators synchronized by a regulator; it is able to make a self-assessment and adjust to alterations in the environment. In particular, an innovative smart actuator has been designed and developed to satisfy machining requirements during active vibration control. This study presents the mechatronic model based on the kinematic and dynamic analysis of the AVC device. To ensure a real time performance, a H2-LQG controller has been developed and validated by simulations involving a machine tool, PZT actuator and controller models. The Hardware in the Loop (HIL) architecture is adopted to control and attenuate the vibrations. A set of experimental tests has been performed to validate the AVC module on a commercial machine tool. The feasibility of the real time vibration damping is demonstrated and the simulation accuracy is evaluated.

Reversal of the lattice structure in SrCoO(x) epitaxial thin films studied by real-time optical spectroscopy and first-principles calculations.

Science.gov (United States)

Choi, Woo Seok; Jeen, Hyoungjeen; Lee, Jun Hee; Seo, S S Ambrose; Cooper, Valentino R; Rabe, Karin M; Lee, Ho Nyung

2013-08-30

Using real-time spectroscopic ellipsometry, we directly observed a reversible lattice and electronic structure evolution in SrCoO(x) (x=2.5-3) epitaxial thin films. Drastically different electronic ground states, which are extremely susceptible to the oxygen content x, are found in the two topotactic phases: i.e., the brownmillerite SrCoO2.5 and the perovskite SrCoO3. First-principles calculations confirmed substantial differences in the electronic structure, including a metal-insulator transition, which originate from the modification in the Co valence states and crystallographic structures. More interestingly, the two phases can be reversibly controlled by changing the ambient pressure at greatly reduced temperatures. Our finding provides an important pathway to understanding the novel oxygen-content-dependent phase transition uniquely found in multivalent transition metal oxides.

Evaluating viral interference between Influenza virus and Newcastle disease virus using real-time reverse transcription–polymerase chain reaction in chicken eggs

Directory of Open Access Journals (Sweden)

Ge Shengqiang

2012-07-01

Full Text Available Abstract Background Simultaneous and sequential allantoic cavity inoculations of Specific-pathogen-free (SPF chicken eggs with Influenza virus (AIV and Newcastle disease virus (NDV demonstrated that the interaction of AIV and NDV during co-infection was variable. Our research revisited the replication interference potential of AIV and NDV using real-time reverse transcription–polymerase chain reaction (real-time RT-PCR for AIV and NDV to specifically detect the viral genomes in mixed infections. Results Data from this survey showed that when different doses of NDV (Lasota or F48E8 and AIV (F98 or H5N1 were simultaneously inoculated into embryonating chicken eggs (ECE, interference with the growth of NDV occurred, while interference with the growth of AIV did not occur. When equal amount of the two viruses were sequentially employed, the degree of interference was dependent upon the time of superinfection and the virulence of virus. Conclusion AIV have a negative impact on NDV growth if they are inoculated simultaneously or sequentially and that the degree of interference depended upon the quantity and relative virulence of the virus strains used; however, interference with AIV was not observed. Only if NDV were inoculated at an earlier time will NDV able to interfere with the growth of AIV.

Real-time communication protocols: an overview

NARCIS (Netherlands)

Hanssen, F.T.Y.; Jansen, P.G.

2003-01-01

This paper describes several existing data link layer protocols that provide real-time capabilities on wired networks, focusing on token-ring and Carrier Sense Multiple Access based networks. Existing modifications to provide better real-time capabilities and performance are also described. Finally

Real-time supervision of building HVAC system performance

Energy Technology Data Exchange (ETDEWEB)

Djuric, Natasa

2008-07-01

building maintenance structure and the real hydronic heating system faults. Coupled simulation and optimization programs (EnergyPlus and GenOpt) were utilized for improving the building performances. These tools were used for improving the design and the control strategies in the HVAC systems. Buildings with a hydronic heating system were analyzed for the purpose of improving the design. Since there are issues in using the optimization tool, GenOpt, a few procedures for different practical problems have been suggested. The optimization results show that the choice of the optimization functions influences significantly the design parameters for the hydronic heating system. Since building construction and equipment characteristics are changing over time, there is a need to find new control strategies which can meet the actual building demand. This problem has been also elaborated on by using EnergyPlus and GenOpt. The control strategies in two different HVAC systems were analyzed, including the hydronic heating system and the ventilation system with the recovery wheel. The developed approach for the strategy optimization includes: involving the optimization variables and the objective function and developing information flow for handling the optimization process. The real data obtained from BEMS and the additional measurements have been utilized to explain faults in the hydronic heating system. To couple real data and the simple heat balance model, the procedure for the model calibration by use of an optimization algorithm has been developed. Using this model, three operating faults in the hydronic heating system have been elaborated. Using the simulation tools EnergyPlus and TRNSYS, several fault detection and diagnosis (FDD) rules have been generated. The FDD rules were established in three steps: testing different faults, calculating the performance indices (PI), and classifying the observed PIs. These rules have been established for the air cooling system and the

Acquisition performance of LAPAN-A3/IPB multispectral imager in real-time mode of operation

Science.gov (United States)

Hakim, P. R.; Permala, R.; Jayani, A. P. S.

2018-05-01

LAPAN-A3/IPB satellite was launched in June 2016 and its multispectral imager has been producing Indonesian coverage images. In order to improve its support for remote sensing application, the imager should produce images with high quality and quantity. To improve the quantity of LAPAN-A3/IPB multispectral image captured, image acquisition could be executed in real-time mode from LAPAN ground station in Bogor when the satellite passes west Indonesia region. This research analyses the performance of LAPAN-A3/IPB multispectral imager acquisition in real-time mode, in terms of image quality and quantity, under assumption of several on-board and ground segment limitations. Results show that with real-time operation mode, LAPAN-A3/IPB multispectral imager could produce twice as much as image coverage compare to recorded mode. However, the images produced in real-time mode will have slightly degraded quality due to image compression process involved. Based on several analyses that have been done in this research, it is recommended to use real-time acquisition mode whenever it possible, unless for some circumstances that strictly not allow any quality degradation of the images produced.

Parity- and time-reversal-violating moments of light nuclei

Energy Technology Data Exchange (ETDEWEB)

Vries, Jordy de, E-mail: devries@kvi.nl [KVI, theory group (Netherlands)

2013-03-15

I present the calculation of parity- and time-reversal-violating moments of the nucleon and light nuclei, originating from the QCD {theta}-bar term and effective dimension-six operators. By applying chiral effective field theory these calculations are performed in a unified framework. I argue that measurements of a few light-nuclear electric dipole moments would shed light on the mechanism of parity and time-reversal violation.

Practical performance of real-time shot-noise measurement in continuous-variable quantum key distribution

Science.gov (United States)

Wang, Tao; Huang, Peng; Zhou, Yingming; Liu, Weiqi; Zeng, Guihua

2018-01-01

In a practical continuous-variable quantum key distribution (CVQKD) system, real-time shot-noise measurement (RTSNM) is an essential procedure for preventing the eavesdropper exploiting the practical security loopholes. However, the performance of this procedure itself is not analyzed under the real-world condition. Therefore, we indicate the RTSNM practical performance and investigate its effects on the CVQKD system. In particular, due to the finite-size effect, the shot-noise measurement at the receiver's side may decrease the precision of parameter estimation and consequently result in a tight security bound. To mitigate that, we optimize the block size for RTSNM under the ensemble size limitation to maximize the secure key rate. Moreover, the effect of finite dynamics of amplitude modulator in this scheme is studied and its mitigation method is also proposed. Our work indicates the practical performance of RTSNM and provides the real secret key rate under it.

Investigations on the frequency of norovirus contamination of ready-to-eat food items in Istanbul, Turkey, by using real-time reverse transcription PCR.

Science.gov (United States)

Yilmaz, Aysun; Bostan, Kamil; Altan, Eda; Muratoglu, Karlo; Turan, Nuri; Tan, Derya; Helps, Christopher; Yilmaz, Huseyin

2011-05-01

Investigation of norovirus (NoV) contamination of food items is important because many outbreaks occur after consumption of contaminated shellfish, vegetables, fruits, and water. The frequency of NoV contamination in food items has not previously been investigated in Turkey. The aim of this study was to investigate the frequency of human NoV genogroups (G) I and II in ready-to-eat tomatoes, parsley, green onion, lettuce, mixed salads, and cracked wheat balls. RNA was extracted with the RNeasy Mini Kit, and a real-time reverse transcription (RT) PCR assay was performed using primers specific for NoV GI and GII. Among the 525 samples analyzed, NoV GII was detected in 1 green onion sample and 1 tomato sample by both SYBR Green and TaqMan real-time RT-PCR assays; no GI virus was detected. The Enterobactericaeae and Escherichia coli levels in the NoV-positive green onion were 6.56 and 1.28 log CFU/g, and those in the tomato were 5.55 and 1.30 log CFU/g, respectively. No significant difference in the bacterial levels was found between the NoV-positive and NoV-negative samples. This study is the first in which NoV GII was found in ready-to-eat food collected from Istanbul, Turkey; thus, these foods may be considered a risk to human health. Epidemiological studies and measures to prevent NoV infection should be considered.

Time-Reversal MUSIC Imaging with Time-Domain Gating Technique

Science.gov (United States)

Choi, Heedong; Ogawa, Yasutaka; Nishimura, Toshihiko; Ohgane, Takeo

A time-reversal (TR) approach with multiple signal classification (MUSIC) provides super-resolution for detection and localization using multistatic data collected from an array antenna system. The theory of TR-MUSIC assumes that the number of antenna elements is greater than that of scatterers (targets). Furthermore, it requires many sets of frequency-domain data (snapshots) in seriously noisy environments. Unfortunately, these conditions are not practical for real environments due to the restriction of a reasonable antenna structure as well as limited measurement time. We propose an approach that treats both noise reduction and relaxation of the transceiver restriction by using a time-domain gating technique accompanied with the Fourier transform before applying the TR-MUSIC imaging algorithm. Instead of utilizing the conventional multistatic data matrix (MDM), we employ a modified MDM obtained from the gating technique. The resulting imaging functions yield more reliable images with only a few snapshots regardless of the limitation of the antenna arrays.

Time reversal technique for gas leakage detection.

Science.gov (United States)

Maksimov, A O; Polovinka, Yu A

2015-04-01

The acoustic remote sensing of subsea gas leakage traditionally uses sonars as active acoustic sensors and hydrophones picking up the sound generated by a leak as passive sensors. When gas leaks occur underwater, bubbles are produced and emit sound at frequencies intimately related to their sizes. The experimental implementation of an acoustic time-reversal mirror (TRM) is now well established in underwater acoustics. In the basic TRM experiment, a probe source emits a pulse that is received on an array of sensors, time reversed, and re-emitted. After time reversal, the resulting field focuses back at the probe position. In this study, a method for enhancing operation of the passive receiving system has been proposed by using it in the regime of TRM. Two factors, the local character of the acoustic emission signal caused by the leakage and a resonant nature of the bubble radiation at their birth, make particularly effective scattering with the conjugate wave (CW). Analytical calculations are performed for the scattering of CW wave on a single bubble when CW is formed by bubble birthing wail received on an array, time reversed, and re-emitted. The quality of leakage detection depends on the spatio-temporal distribution of ambient noise.

Sensitivity and specificity of real-time reverse transcription polymerase chain reaction, histopathology, and immunohistochemical labeling for the detection of Rift Valley fever virus in naturally infected cattle and sheep.

Science.gov (United States)

Odendaal, Lieza; Fosgate, Geoffrey T; Romito, Marco; Coetzer, Jacobus A W; Clift, Sarah J

2014-01-01

Real-time reverse transcription polymerase chain reaction (real-time RT-PCR), histopathology, and immunohistochemical labeling (IHC) were performed on liver specimens from 380 naturally infected cattle and sheep necropsied during the 2010 Rift Valley fever (RVF) epidemic in South Africa. Sensitivity (Se) and specificity (Sp) of real-time RT-PCR, histopathology, and IHC were estimated in a latent-class model using a Bayesian framework. The Se and Sp of real-time RT-PCR were estimated as 97.4% (95% confidence interval [CI] = 95.2-98.8%) and 71.7% (95% CI = 65-77.9%) respectively. The Se and Sp of histopathology were estimated as 94.6% (95% CI = 91-97.2%) and 92.3% (95% CI = 87.6-95.8%), respectively. The Se and Sp of IHC were estimated as 97.6% (95% CI = 93.9-99.8%) and 99.4% (95% CI = 96.9-100%), respectively. Decreased Sp of real-time RT-PCR was ascribed to cross-contamination of samples. Stratified analysis of the data suggested variations in test accuracy with fetuses and severely autolyzed specimens. The Sp of histopathology in fetuses (83%) was 9.3% lower than the sample population (92.3%). The Se of IHC decreased from 97.6% to 81.5% in the presence of severe autolysis. The diagnostic Se and Sp of histopathology was higher than expected, confirming the value of routine postmortem examinations and histopathology of liver specimens. Aborted fetuses, however, should be screened using a variety of tests in areas endemic for RVF, and results from severely autolyzed specimens should be interpreted with caution. The most feasible testing option for countries lacking suitably equipped laboratories seems to be routine histology in combination with IHC.

Research in Distributed Real-Time Systems

Science.gov (United States)

Mukkamala, R.

1997-01-01

This document summarizes the progress we have made on our study of issues concerning the schedulability of real-time systems. Our study has produced several results in the scalability issues of distributed real-time systems. In particular, we have used our techniques to resolve schedulability issues in distributed systems with end-to-end requirements. During the next year (1997-98), we propose to extend the current work to address the modeling and workload characterization issues in distributed real-time systems. In particular, we propose to investigate the effect of different workload models and component models on the design and the subsequent performance of distributed real-time systems.

Progress towards steady-state operation and real time control of internal transport barriers in JET

International Nuclear Information System (INIS)

Litaudon, X.

2002-01-01

In JET advanced tokamak research mainly focuses on plasmas with internal transport barriers (ITBs), generated by modifications of the current profile. The formerly developed optimised shear regime with low magnetic shear in the plasma center has been extended to deeply reversed magnetic shear configurations. ITBs occur at much lower access powers. The achievement of high fusion performance is reported in deeply reversed magnetic shear configuration. The generation of plasmas with wide ITBs in this configuration has allowed an extension of the accessible normalised toroidal beta at high magnetic field. We report on the successful sustainment and control of the electron and ion ITB in full current drive operation with a large fraction of bootstrap current. Progress towards the steady state capability of ITB plasmas includes techniques to avoid strong ELM activity and the newly developed real time control of the local ITB strength. Thanks to the real time control of the ITB characteristics the improved confinement state is maintained in a more reproducible and stable manner in quasi-stationary conditions. (author)

Test of feasibility of a novel high precision test of time reversal invariance

International Nuclear Information System (INIS)

Samuel, Deepak

2007-01-01

The first results of a feasibility test of a novel high precision test of time reversal invariance are reported. The Time Reversal Invariance test at COSY (TRIC) was planned to measure the time reversal violating observable A y,xz with an accuracy of 10 -6 in proton-deuteron (p-d) scattering. A novel technique for measuring total cross sections is introduced and the achievable precision of this measuring technique is tested. The correlation coefficient A y,y in p-d scattering fakes a time-reversal violating effect. This work reports the feasibility test of the novel method in the measurement of A y,y in p-p scattering. The first step in the experimental design was the development of a hard real-time data acquisition system. To meet stringent latency requirements, the capabilities of Windows XP had to be augmented with a real-time subsystem. The remote control feature of the data acquisition enables users to operate it from any place via an internet connection. The data acquisition proved its reliability in several beam times without any failures. The analysis of the data showed the presence of 1/f noise which substantially limits the quality of our measurements. The origin of 1/f noise was traced and found to be the Barkhausen noise from the ferrite core of the beam current transformer (BCT). A global weighted fitting technique based on a modified Wiener-Khinchin method was developed and used to suppress the influence of 1/f noise, which increased the error bar of the results by a factor 3. This is the only deviation from our expectations. The results are presented and discussed. (orig.)

Test of feasibility of a novel high precision test of time reversal invariance

Energy Technology Data Exchange (ETDEWEB)

Samuel, Deepak

2007-07-01

The first results of a feasibility test of a novel high precision test of time reversal invariance are reported. The Time Reversal Invariance test at COSY (TRIC) was planned to measure the time reversal violating observable A{sub y,xz} with an accuracy of 10{sup -6} in proton-deuteron (p-d) scattering. A novel technique for measuring total cross sections is introduced and the achievable precision of this measuring technique is tested. The correlation coefficient A{sub y,y} in p-d scattering fakes a time-reversal violating effect. This work reports the feasibility test of the novel method in the measurement of A{sub y,y} in p-p scattering. The first step in the experimental design was the development of a hard real-time data acquisition system. To meet stringent latency requirements, the capabilities of Windows XP had to be augmented with a real-time subsystem. The remote control feature of the data acquisition enables users to operate it from any place via an internet connection. The data acquisition proved its reliability in several beam times without any failures. The analysis of the data showed the presence of 1/f noise which substantially limits the quality of our measurements. The origin of 1/f noise was traced and found to be the Barkhausen noise from the ferrite core of the beam current transformer (BCT). A global weighted fitting technique based on a modified Wiener-Khinchin method was developed and used to suppress the influence of 1/f noise, which increased the error bar of the results by a factor 3. This is the only deviation from our expectations. The results are presented and discussed. (orig.)

Neural network evaluation of tokamak current profiles for real time control (abstract)

Science.gov (United States)

Wróblewski, Dariusz

1997-01-01

Active feedback control of the current profile, requiring real-time determination of the current profile parameters, is envisioned for tokamaks operating in enhanced confinement regimes. The distribution of toroidal current in a tokamak is now routinely evaluated based on external (magnetic probes, flux loops) and internal (motional Stark effect) measurements of the poloidal magnetic field. However, the analysis involves reconstruction of magnetohydrodynamic equilibrium and is too intensive computationally to be performed in real time. In the present study, a neural network is used to provide a mapping from the magnetic measurements (internal and external) to selected parameters of the safety factor profile. The single-pass, feedforward calculation of output of a trained neural network is very fast, making this approach particularly suitable for real-time applications. The network was trained on a large set of simulated equilibrium data for the DIII-D tokamak. The database encompasses a large variety of current profiles including the hollow current profiles important for reversed central shear operation. The parameters of safety factor profile (a quantity related to the current profile through the magnetic field tilt angle) estimated by the neural network include central safety factor, q0, minimum value of q, qmin, and the location of qmin. Very good performance of the trained neural network both for simulated test data and for experimental data is demonstrated.

Neural network evaluation of tokamak current profiles for real time control (abstract)

International Nuclear Information System (INIS)

Wroblewski, D.

1997-01-01

Active feedback control of the current profile, requiring real-time determination of the current profile parameters, is envisioned for tokamaks operating in enhanced confinement regimes. The distribution of toroidal current in a tokamak is now routinely evaluated based on external (magnetic probes, flux loops) and internal (motional Stark effect) measurements of the poloidal magnetic field. However, the analysis involves reconstruction of magnetohydrodynamic equilibrium and is too intensive computationally to be performed in real time. In the present study, a neural network is used to provide a mapping from the magnetic measurements (internal and external) to selected parameters of the safety factor profile. The single-pass, feedforward calculation of output of a trained neural network is very fast, making this approach particularly suitable for real-time applications. The network was trained on a large set of simulated equilibrium data for the DIII-D tokamak. The database encompasses a large variety of current profiles including the hollow current profiles important for reversed central shear operation. The parameters of safety factor profile (a quantity related to the current profile through the magnetic field tilt angle) estimated by the neural network include central safety factor, q 0 , minimum value of q, q min , and the location of q min . Very good performance of the trained neural network both for simulated test data and for experimental data is demonstrated. copyright 1997 American Institute of Physics

Progress towards steady-state operation and real time control of internal transport barriers in JET

International Nuclear Information System (INIS)

Litaudon, X.; Becoulet, A.; Crisanti, F.

2003-01-01

In JET advanced tokamak research mainly focuses on plasmas with internal transport barriers (ITBs), generated by modifications of the current profile. The formerly developed optimised shear regime with low magnetic shear in the plasma center has been extended to deeply reversed magnetic shear configurations. High fusion performance with wide ITBs has been obtained transiently in deeply reversed magnetic shear configuration: H IPB98(y,2) ∼1.9, β N =2.4 at I p =2.5MA. At somewhat reduced performance electron and ion ITBs have been sustained in full current drive operation with 1MA of bootstrap current: H IPB98(y,2) ∼1, β N =1.7 at I p =2.0MA. The ITBs have been maintained up to 11s. This duration, much larger than the energy confinement time (37 times larger), is already approaching a current resistive time. New real-time measurements and feedback control algorithms have been developed and implemented in JET for successfully controlling the ITB dynamics and the current density profile in the highly non-inductive regime. (author)

PERTS: A Prototyping Environment for Real-Time Systems

Science.gov (United States)

Liu, Jane W. S.; Lin, Kwei-Jay; Liu, C. L.

1993-01-01

PERTS is a prototyping environment for real-time systems. It is being built incrementally and will contain basic building blocks of operating systems for time-critical applications, tools, and performance models for the analysis, evaluation and measurement of real-time systems and a simulation/emulation environment. It is designed to support the use and evaluation of new design approaches, experimentations with alternative system building blocks, and the analysis and performance profiling of prototype real-time systems.

Reverse alignment "mirror image" visualization as a laparoscopic training tool improves task performance.

Science.gov (United States)

Dunnican, Ward J; Singh, T Paul; Ata, Ashar; Bendana, Emma E; Conlee, Thomas D; Dolce, Charles J; Ramakrishnan, Rakesh

2010-06-01

Reverse alignment (mirror image) visualization is a disconcerting situation occasionally faced during laparoscopic operations. This occurs when the camera faces back at the surgeon in the opposite direction from which the surgeon's body and instruments are facing. Most surgeons will attempt to optimize trocar and camera placement to avoid this situation. The authors' objective was to determine whether the intentional use of reverse alignment visualization during laparoscopic training would improve performance. A standard box trainer was configured for reverse alignment, and 34 medical students and junior surgical residents were randomized to train with either forward alignment (DIRECT) or reverse alignment (MIRROR) visualization. Enrollees were tested on both modalities before and after a 4-week structured training program specific to their modality. Student's t test was used to determine differences in task performance between the 2 groups. Twenty-one participants completed the study (10 DIRECT, 11 MIRROR). There were no significant differences in performance time between DIRECT or MIRROR participants during forward or reverse alignment initial testing. At final testing, DIRECT participants had improved times only in forward alignment performance; they demonstrated no significant improvement in reverse alignment performance. MIRROR participants had significant time improvement in both forward and reverse alignment performance at final testing. Reverse alignment imaging for laparoscopic training improves task performance for both reverse alignment and forward alignment tasks. This may be translated into improved performance in the operating room when faced with reverse alignment situations. Minimal lab training can account for drastic adaptation to this environment.

Introduction to time reversal theory

International Nuclear Information System (INIS)

Henley, E.M.

1987-01-01

Theory and reaction mechanisms relevant to time reversal invariance are reviewed. Consequences of time reversal invariance are presented under the headings of CP tests, electromagnetic moments, weak emissions or absorptions, and scattering reactions. 8 refs., 4 figs

Performance Evaluation of a Synthetic Aperture Real-Time Ultrasound System

DEFF Research Database (Denmark)

Stuart, Matthias Bo; Tomov, Borislav Gueorguiev; Jensen, Jørgen Arendt

2011-01-01

This paper evaluates the signal-to-noise ratio, the time stability, and the phase difference of the sampling in the experimental ultrasound scanner SARUS: A synthetic aperture, real-time ultrasound system. SARUS has 1024 independent transmit and receive channels and is capable of handling 2D probes...... arrays (FPGAs) making it very flexible and allowing implementation of other real-time ultrasound processing methods in the future. For conventional B-mode imaging, a penetration depth around 7 cm for a 7 MHz transducer is obtained (signal-tonoise ratio of 0 dB), which is comparable to commercial...... for 3D ultrasound imaging. It samples at 12 bits per sample and has a sampling rate of 70 MHz with the possibility of decimating the sampling frequency at the input. SARUS is capable of advanced real-time computations such as synthetic aperture imaging. The system is built using fieldprogrammable gate...

Integration of MDSplus in real-time systems

International Nuclear Information System (INIS)

Luchetta, A.; Manduchi, G.; Taliercio, C.

2006-01-01

RFX-mod makes extensive usage of real-time systems for feedback control and uses MDSplus to interface them to the main Data Acquisition system. For this purpose, the core of MDSplus has been ported to VxWorks, the operating system used for real-time control in RFX. Using this approach, it is possible to integrate real-time systems, but MDSplus is used only for non-real-time tasks, i.e. those tasks which are executed before and after the pulse and whose performance does not affect the system time constraints. More extensive use of MDSplus in real-time systems is foreseen, and a real-time layer for MDSplus is under development, which will provide access to memory-mapped pulse files, shared by the tasks running on the same CPU. Real-time communication will also be integrated in the MDSplus core to provide support for distributed memory-mapped pulse files

Real time programming environment for Windows

Energy Technology Data Exchange (ETDEWEB)

LaBelle, D.R. [LaBelle (Dennis R.), Clifton Park, NY (United States)

1998-04-01

This document provides a description of the Real Time Programming Environment (RTProE). RTProE tools allow a programmer to create soft real time projects under general, multi-purpose operating systems. The basic features necessary for real time applications are provided by RTProE, leaving the programmer free to concentrate efforts on his specific project. The current version supports Microsoft Windows{trademark} 95 and NT. The tasks of real time synchronization and communication with other programs are handled by RTProE. RTProE includes a generic method for connecting a graphical user interface (GUI) to allow real time control and interaction with the programmer`s product. Topics covered in this paper include real time performance issues, portability, details of shared memory management, code scheduling, application control, Operating System specific concerns and the use of Computer Aided Software Engineering (CASE) tools. The development of RTProE is an important step in the expansion of the real time programming community. The financial costs associated with using the system are minimal. All source code for RTProE has been made publicly available. Any person with access to a personal computer, Windows 95 or NT, and C or FORTRAN compilers can quickly enter the world of real time modeling and simulation.

Real time monitoring of electron processors

International Nuclear Information System (INIS)

Nablo, S.V.; Kneeland, D.R.; McLaughlin, W.L.

1995-01-01

A real time radiation monitor (RTRM) has been developed for monitoring the dose rate (current density) of electron beam processors. The system provides continuous monitoring of processor output, electron beam uniformity, and an independent measure of operating voltage or electron energy. In view of the device's ability to replace labor-intensive dosimetry in verification of machine performance on a real-time basis, its application to providing archival performance data for in-line processing is discussed. (author)

Real-time monitoring through the use of technology to enhance performances throughout HIV cascades.

Science.gov (United States)

Avery, Matthew; Mills, Stephen J; Stephan, Eric

2017-09-01

Controlling the HIV epidemic requires strong linkages across a 'cascade' of prevention, testing, and treatment services. Information and communications technology (ICT) offers the potential to monitor and improve the performance of this HIV cascade in real time. We assessed recent (media to expand reach and improve programmatic targeting; technology in healthcare settings to strengthen coordination, guide clinical decision-making and improve clinical interactions; and telephone-based follow-up to improve treatment retention and adherence. With exceptions, publications have tended to be descriptive rather than evaluative, and the evidence-base for the effectiveness of ICT-driven interventions remains mixed. There is widespread recognition of the potential for ICT to improve HIV cascade performance, but with significant challenges. Successful implementation of real-time cascade monitoring will depend upon stakeholder engagement, compatibility with existing workflows, appropriate resource allocation, and managing expectations.

Status of time reversal invariance

International Nuclear Information System (INIS)

Henley, E.M.

1989-01-01

Time Reversal Invariance is introduced, and theories for its violation are reviewed. The present experimental and theoretical status of Time Reversal Invariance and tests thereof will be presented. Possible future tests will be discussed. 30 refs., 2 figs., 1 tab

A real-time architecture for time-aware agents.

Science.gov (United States)

Prouskas, Konstantinos-Vassileios; Pitt, Jeremy V

2004-06-01

This paper describes the specification and implementation of a new three-layer time-aware agent architecture. This architecture is designed for applications and environments where societies of humans and agents play equally active roles, but interact and operate in completely different time frames. The architecture consists of three layers: the April real-time run-time (ART) layer, the time aware layer (TAL), and the application agents layer (AAL). The ART layer forms the underlying real-time agent platform. An original online, real-time, dynamic priority-based scheduling algorithm is described for scheduling the computation time of agent processes, and it is shown that the algorithm's O(n) complexity and scalable performance are sufficient for application in real-time domains. The TAL layer forms an abstraction layer through which human and agent interactions are temporally unified, that is, handled in a common way irrespective of their temporal representation and scale. A novel O(n2) interaction scheduling algorithm is described for predicting and guaranteeing interactions' initiation and completion times. The time-aware predicting component of a workflow management system is also presented as an instance of the AAL layer. The described time-aware architecture addresses two key challenges in enabling agents to be effectively configured and applied in environments where humans and agents play equally active roles. It provides flexibility and adaptability in its real-time mechanisms while placing them under direct agent control, and it temporally unifies human and agent interactions.

Time reversal tests in polarized neutron reactions

International Nuclear Information System (INIS)

Asahi, Koichiro; Bowman, J.D.; Crawford, B.

1998-01-01

This is the final report of a three-year, Laboratory-Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). In recent years the nuclear weak interaction has been studied in the compound nucleus via parity violation. The observed parity-violating effects are strongly enhanced by nuclear structure. The predictions are that the interaction of polarized neutrons with polarized nuclear targets could be also used to perform sensitive tests of time-reversal-violation because of the nuclear enhancements. The author has designed experiments to search for time-reversal violation in neutron-nucleus interactions. He has also developed techniques to polarize neutrons with laser-polarized 3 He gas targets. Using the polarized 3 He neutron spin filter, he has performed two experiments at LANSCE: an absolute neutron beam polarization measurement with an accuracy of 0.2--0.3% and a neutron spin-rotation measurement on a 139 La sample

Comparison of real-time reverse transcriptase polymerase chain reaction of peripheral blood mononuclear cells, serum and cell-free body cavity effusion for the diagnosis of feline infectious peritonitis.

Science.gov (United States)

Doenges, Stephanie J; Weber, Karin; Dorsch, Roswitha; Fux, Robert; Hartmann, Katrin

2017-04-01

Objectives Diagnosis of feline infectious peritonitis (FIP) remains challenging, especially in cats without effusions. The objective of this study was to evaluate the sensitivity and specificity of a real-time reverse transcriptase polymerase chain reaction (RT-PCR) detecting feline coronavirus (FCoV) RNA in peripheral blood mononuclear cells (PBMCs) and serum in comparison with the same real-time RT-PCR in cell-free body cavity effusion. Methods This prospective case-control study included 92 cats. Forty-three cats had a definitive diagnosis of FIP, established either by histopathological examination (n = 28) or by positive immunofluorescence staining of FCoV antigen in macrophages of effusions (n = 11), or by both methods (n = 4). Forty-nine control cats had other diseases but similar clinical signs. Real-time RT-PCR was performed on PBMCs of 37 cats (21 cats with FIP, 16 controls), on serum of 51 cats (26 cats with FIP, 25 controls) and on cell-free body cavity effusion of 69 cats (36 cats with FIP, 33 controls). Sensitivity, specificity, positive and negative predictive value, including 95% confidence intervals (CI), were calculated. Results Real-time RT-PCR of PBMCs, serum and cell-free body cavity effusion showed a specificity of 100% (95% CI 79.4-100% in PBMCs, 86.3-100% in serum, 89.4-100% in cell-free body cavity effusion) and a sensitivity of 28.6% (95% CI 11.3-52.2%) in PBMCs, 15.4% (95% CI 4.4-34.9%) in serum and 88.9% (95% CI 73.9-96.9%) in cell-free body cavity effusion to diagnose FIP. Conclusions and relevance Although it is known that RT-PCR can often provide false-positive results in healthy cats, this real-time RT-PCR was shown to be a specific tool for the diagnosis of FIP when applied in a clinical setting. Sensitivity in cell-free body cavity effusion was high but low in PBMCs and serum. PBMC samples showed a higher sensitivity than serum samples, and are therefore a better choice if no effusion is present.

Real Time Revisited

Science.gov (United States)

Allen, Phillip G.

1985-12-01

The call for abolishing photo reconnaissance in favor of real time is once more being heard. Ten years ago the same cries were being heard with the introduction of the Charge Coupled Device (CCD). The real time system problems that existed then and stopped real time proliferation have not been solved. The lack of an organized program by either DoD or industry has hampered any efforts to solve the problems, and as such, very little has happened in real time in the last ten years. Real time is not a replacement for photo, just as photo is not a replacement for infra-red or radar. Operational real time sensors can be designed only after their role has been defined and improvements made to the weak links in the system. Plodding ahead on a real time reconnaissance suite without benefit of evaluation of utility will allow this same paper to be used ten years from now.

Real-time data access layer for MDSplus

International Nuclear Information System (INIS)

Manduchi, G.; Luchetta, A.; Taliercio, C.; Fredian, T.; Stillerman, J.

2008-01-01

Recent extensions to MDSplus allow data handling in long discharges and provide a real-time data access and communication layer. The real-time data access layer is an additional component of MDSplus: it is possible to use the traditional MDSplus API during normal operation, and to select a subset of data items to be used in real time. Real-time notification is provided by a communication layer using a publish-subscribe pattern. The notification covers processes sharing the same data items even running on different machines, thus allowing the implementation of distributed control systems. The real-time data access layer has been developed for Windows, Linux, and VxWorks; it is currently being ported to Linux RTAI. In order to quantify the fingerprint of the presented system, the performance of the real-time access layer approach is compared with that of an ad hoc, manually optimized program in a sample real-time application

Real-time communication for distributed plasma control systems

Energy Technology Data Exchange (ETDEWEB)

Luchetta, A. [Consorzio RFX, Associazione Euratom-ENEA sulla Fusione, Corso Stati Uniti 4, Padova 35127 (Italy)], E-mail: adriano.luchetta@igi.cnr.it; Barbalace, A.; Manduchi, G.; Soppelsa, A.; Taliercio, C. [Consorzio RFX, Associazione Euratom-ENEA sulla Fusione, Corso Stati Uniti 4, Padova 35127 (Italy)

2008-04-15

Real-time control applications will benefit in the near future from the enhanced performance provided by multi-core processor architectures. Nevertheless real-time communication will continue to be critical in distributed plasma control systems where the plant under control typically is distributed over a wide area. At RFX-mod real-time communication is crucial for hard real-time plasma control, due to the distributed architecture of the system, which consists of several VMEbus stations. The system runs under VxWorks and uses Gigabit Ethernet for sub-millisecond real-time communication. To optimize communication in the system, a set of detailed measurements has been carried out on the target platforms (Motorola MVME5100 and MVME5500) using either the VxWorks User Datagram Protocol (UDP) stack or raw communication based on the data link layer. Measurements have been carried out also under Linux, using its UDP stack or, in alternative, RTnet, an open source hard real-time network protocol stack. RTnet runs under Xenomai or RTAI, two popular real-time extensions based on the Linux kernel. The paper reports on the measurements carried out and compares the results, showing that the performance obtained by using open source code is suitable for sub-millisecond real-time communication in plasma control.

Approaching near real-time biosensing: microfluidic microsphere based biosensor for real-time analyte detection.

Science.gov (United States)

Cohen, Noa; Sabhachandani, Pooja; Golberg, Alexander; Konry, Tania

2015-04-15

In this study we describe a simple lab-on-a-chip (LOC) biosensor approach utilizing well mixed microfluidic device and a microsphere-based assay capable of performing near real-time diagnostics of clinically relevant analytes such cytokines and antibodies. We were able to overcome the adsorption kinetics reaction rate-limiting mechanism, which is diffusion-controlled in standard immunoassays, by introducing the microsphere-based assay into well-mixed yet simple microfluidic device with turbulent flow profiles in the reaction regions. The integrated microsphere-based LOC device performs dynamic detection of the analyte in minimal amount of biological specimen by continuously sampling micro-liter volumes of sample per minute to detect dynamic changes in target analyte concentration. Furthermore we developed a mathematical model for the well-mixed reaction to describe the near real time detection mechanism observed in the developed LOC method. To demonstrate the specificity and sensitivity of the developed real time monitoring LOC approach, we applied the device for clinically relevant analytes: Tumor Necrosis Factor (TNF)-α cytokine and its clinically used inhibitor, anti-TNF-α antibody. Based on the reported results herein, the developed LOC device provides continuous sensitive and specific near real-time monitoring method for analytes such as cytokines and antibodies, reduces reagent volumes by nearly three orders of magnitude as well as eliminates the washing steps required by standard immunoassays. Copyright © 2014 Elsevier B.V. All rights reserved.

Validation and Assessment of Multi-GNSS Real-Time Precise Point Positioning in Simulated Kinematic Mode Using IGS Real-Time Service

Directory of Open Access Journals (Sweden)

Liang Wang

2018-02-01

Full Text Available Precise Point Positioning (PPP is a popular technology for precise applications based on the Global Navigation Satellite System (GNSS. Multi-GNSS combined PPP has become a hot topic in recent years with the development of multiple GNSSs. Meanwhile, with the operation of the real-time service (RTS of the International GNSS Service (IGS agency that provides satellite orbit and clock corrections to broadcast ephemeris, it is possible to obtain the real-time precise products of satellite orbits and clocks and to conduct real-time PPP. In this contribution, the real-time multi-GNSS orbit and clock corrections of the CLK93 product are applied for real-time multi-GNSS PPP processing, and its orbit and clock qualities are investigated, first with a seven-day experiment by comparing them with the final multi-GNSS precise product ‘GBM’ from GFZ. Then, an experiment involving real-time PPP processing for three stations in the Multi-GNSS Experiment (MGEX network with a testing period of two weeks is conducted in order to evaluate the convergence performance of real-time PPP in a simulated kinematic mode. The experimental result shows that real-time PPP can achieve a convergence performance of less than 15 min for an accuracy level of 20 cm. Finally, the real-time data streams from 12 globally distributed IGS/MGEX stations for one month are used to assess and validate the positioning accuracy of real-time multi-GNSS PPP. The results show that the simulated kinematic positioning accuracy achieved by real-time PPP on different stations is about 3.0 to 4.0 cm for the horizontal direction and 5.0 to 7.0 cm for the three-dimensional (3D direction.

Distributed Issues for Ada Real-Time Systems

Science.gov (United States)

1990-07-23

NUMBERS Distributed Issues for Ada Real - Time Systems MDA 903-87- C- 0056 S. AUTHOR(S) Thomas E. Griest 7. PERFORMING ORGANiZATION NAME(S) AND ADORESS(ES) 8...considerations. I Adding to the problem of distributed real - time systems is the issue of maintaining a common sense of time among all of the processors...because -omeone is waiting for the final output of a very large set of computations. However in real - time systems , consistent meeting of short-term

Performance results of cooperating expert systems in a distributed real-time monitoring system

Science.gov (United States)

Schwuttke, U. M.; Veregge, J. R.; Quan, A. G.

1994-01-01

data, hierarchical reporting of problems that extend beyond a single domain, and shared responsibility for problems that overlap domains. The system enables efficient diagnosis of complex system failures in real-time environments with high data volumes and moderate failure rates, as indicated by extensive performance measurements.

Evaluation and optimization of SYBR Green real-time reverse transcription polymerase chain reaction as a tool for diagnosis of the Flavivirus genus in Brazil

Directory of Open Access Journals (Sweden)

Marilia Farignoli Romeiro

2016-06-01

Full Text Available Abstract: INTRODUCTION: The genus Flavivirus includes several pathogenic species that cause severe illness in humans. Therefore, a rapid and accurate molecular method for diagnosis and surveillance of these viruses would be of great importance. Here, we evaluate and optimize a quantitative real-time reverse transcription polymerase chain reaction (RT-PCR method for the diagnosis of the Flavivirus genus. METHODS: We evaluated different commercial kits that use the SYBR Green system for real-time RT-PCR with a primer set that amplifies a fragment of the NS5 flavivirus gene. The specificity and sensitivity of the assay were tested using twelve flaviviruses and ribonucleic acid (RNA transcribed from the yellow fever virus. Additionally, this assay was evaluated using the sera of 410 patients from different regions of Brazil with acute febrile illness and a negative diagnosis for the dengue virus. RESULTS: The real-time RT-PCR amplified all flaviviruses tested at a melting temperature of 79.92 to 83.49°C. A detection limit of 100 copies per ml was determined for this assay. Surprisingly, we detected dengue virus in 4.1% (17/410 of samples from patients with febrile illness and a supposedly negative dengue infection diagnosis. The viral load in patients ranged from 2.1×107to 3.4×103copies per ml. CONCLUSIONS: The real-time RT-PCR method may be very useful for preliminary diagnoses in screenings, outbreaks, and other surveillance studies. Moreover, this assay can be easily applied to monitor viral activity and to measure viral load in pathogenesis studies.

Fast damage imaging using the time-reversal technique in the frequency–wavenumber domain

International Nuclear Information System (INIS)

Zhu, R; Huang, G L; Yuan, F G

2013-01-01

The time-reversal technique has been successfully used in structural health monitoring (SHM) for quantitative imaging of damage. However, the technique is very time-consuming when it is implemented in the time domain. In this paper, we study the technique in the frequency–wavenumber (f–k) domain for fast real-time imaging of multiple damage sites in plates using scattered flexural plate waves. Based on Mindlin plate theory, the time reversibility of dispersive flexural waves in an isotropic plate is theoretically investigated in the f–k domain. A fast damage imaging technique is developed by using the cross-correlation between the back-propagated scattered wavefield and the incident wavefield in the frequency domain. Numerical simulations demonstrate that the proposed technique cannot only localize multiple damage sites but also potentially identify their sizes. Moreover, the time-reversal technique in the f–k domain is about two orders of magnitude faster than the method in the time domain. Finally, experimental testing of an on-line SHM system with a sparse piezoelectric sensor array is conducted for fast multiple damage identification using the proposed technique. (paper)

Real-time sonography in obstetrics.

Science.gov (United States)

Anderson, S G

1978-03-01

Three hundred fifty real-time scans were performed on pregnant women for various indications. Placental localization was satisfactorily obtained in 173 of 174 studies. Estimates of fetal gestation from directly measured biparietal diameter were +/-2 weeks of actual gestation in 153 of 172 (88.9%) measurements. The presence or absence of fetal motion and cardiac activity established a diagnosis of fetal viability or fetal death in 32 patients after the first trimester. Accurate diagnosis was made in 52 of 57 patients with threatened abortions, and two of these errors occurred in scans performed before completion of the eighth postmenstrual week. Because of the ability to demonstrate fetal motion, real-time sonography should have many applications in obstetrics.

MARTe: A Multiplatform Real-Time Framework

Science.gov (United States)

Neto, André C.; Sartori, Filippo; Piccolo, Fabio; Vitelli, Riccardo; De Tommasi, Gianmaria; Zabeo, Luca; Barbalace, Antonio; Fernandes, Horacio; Valcarcel, Daniel F.; Batista, Antonio J. N.

2010-04-01

Development of real-time applications is usually associated with nonportable code targeted at specific real-time operating systems. The boundary between hardware drivers, system services, and user code is commonly not well defined, making the development in the target host significantly difficult. The Multithreaded Application Real-Time executor (MARTe) is a framework built over a multiplatform library that allows the execution of the same code in different operating systems. The framework provides the high-level interfaces with hardware, external configuration programs, and user interfaces, assuring at the same time hard real-time performances. End-users of the framework are required to define and implement algorithms inside a well-defined block of software, named Generic Application Module (GAM), that is executed by the real-time scheduler. Each GAM is reconfigurable with a set of predefined configuration meta-parameters and interchanges information using a set of data pipes that are provided as inputs and required as output. Using these connections, different GAMs can be chained either in series or parallel. GAMs can be developed and debugged in a non-real-time system and, only once the robustness of the code and correctness of the algorithm are verified, deployed to the real-time system. The software also supplies a large set of utilities that greatly ease the interaction and debugging of a running system. Among the most useful are a highly efficient real-time logger, HTTP introspection of real-time objects, and HTTP remote configuration. MARTe is currently being used to successfully drive the plasma vertical stabilization controller on the largest magnetic confinement fusion device in the world, with a control loop cycle of 50 ?s and a jitter under 1 ?s. In this particular project, MARTe is used with the Real-Time Application Interface (RTAI)/Linux operating system exploiting the new ?86 multicore processors technology.

Dual Combined Real-Time Reverse Transcription Polymerase Chain Reaction Assay for the Diagnosis of Lyssavirus Infection.

Directory of Open Access Journals (Sweden)

Laurent Dacheux

2016-07-01

Full Text Available The definitive diagnosis of lyssavirus infection (including rabies in animals and humans is based on laboratory confirmation. The reference techniques for post-mortem rabies diagnosis are still based on direct immunofluorescence and virus isolation, but molecular techniques, such as polymerase chain reaction (PCR based methods, are increasingly being used and now constitute the principal tools for diagnosing rabies in humans and for epidemiological analyses. However, it remains a key challenge to obtain relevant specificity and sensitivity with these techniques while ensuring that the genetic diversity of lyssaviruses does not compromise detection. We developed a dual combined real-time reverse transcription polymerase chain reaction (combo RT-qPCR method for pan-lyssavirus detection. This method is based on two complementary technologies: a probe-based (TaqMan RT-qPCR for detecting the RABV species (pan-RABV RT-qPCR and a second reaction using an intercalating dye (SYBR Green to detect other lyssavirus species (pan-lyssa RT-qPCR. The performance parameters of this combined assay were evaluated with a large panel of primary animal samples covering almost all the genetic variability encountered at the viral species level, and they extended to almost all lyssavirus species characterized to date. This method was also evaluated for the diagnosis of human rabies on 211 biological samples (positive n = 76 and negative n = 135 including saliva, skin and brain biopsies. It detected all 41 human cases of rabies tested and confirmed the sensitivity and the interest of skin biopsy (91.5% and saliva (54% samples for intra-vitam diagnosis of human rabies. Finally, this method was successfully implemented in two rabies reference laboratories in enzootic countries (Cambodia and Morocco. This combined RT-qPCR method constitutes a relevant, useful, validated tool for the diagnosis of rabies in both humans and animals, and represents a promising tool for

Dual Combined Real-Time Reverse Transcription Polymerase Chain Reaction Assay for the Diagnosis of Lyssavirus Infection.

Science.gov (United States)

Dacheux, Laurent; Larrous, Florence; Lavenir, Rachel; Lepelletier, Anthony; Faouzi, Abdellah; Troupin, Cécile; Nourlil, Jalal; Buchy, Philippe; Bourhy, Herve

2016-07-01

The definitive diagnosis of lyssavirus infection (including rabies) in animals and humans is based on laboratory confirmation. The reference techniques for post-mortem rabies diagnosis are still based on direct immunofluorescence and virus isolation, but molecular techniques, such as polymerase chain reaction (PCR) based methods, are increasingly being used and now constitute the principal tools for diagnosing rabies in humans and for epidemiological analyses. However, it remains a key challenge to obtain relevant specificity and sensitivity with these techniques while ensuring that the genetic diversity of lyssaviruses does not compromise detection. We developed a dual combined real-time reverse transcription polymerase chain reaction (combo RT-qPCR) method for pan-lyssavirus detection. This method is based on two complementary technologies: a probe-based (TaqMan) RT-qPCR for detecting the RABV species (pan-RABV RT-qPCR) and a second reaction using an intercalating dye (SYBR Green) to detect other lyssavirus species (pan-lyssa RT-qPCR). The performance parameters of this combined assay were evaluated with a large panel of primary animal samples covering almost all the genetic variability encountered at the viral species level, and they extended to almost all lyssavirus species characterized to date. This method was also evaluated for the diagnosis of human rabies on 211 biological samples (positive n = 76 and negative n = 135) including saliva, skin and brain biopsies. It detected all 41 human cases of rabies tested and confirmed the sensitivity and the interest of skin biopsy (91.5%) and saliva (54%) samples for intra-vitam diagnosis of human rabies. Finally, this method was successfully implemented in two rabies reference laboratories in enzootic countries (Cambodia and Morocco). This combined RT-qPCR method constitutes a relevant, useful, validated tool for the diagnosis of rabies in both humans and animals, and represents a promising tool for lyssavirus

The FERMI-Elettra distributed real-time framework

International Nuclear Information System (INIS)

Pivetta, L.; Gaio, G.; Passuello, R.; Scalamera, G.

2012-01-01

FERMI-Elettra is a Free Electron Laser (FEL) based on a 1.5 GeV linac. The pulsed operation of the accelerator and the necessity to characterize and control each electron bunch requires synchronous acquisition of the beam diagnostics together with the ability to drive actuators in real-time at the linac repetition rate. The Adeos/Xenomai real-time extensions have been adopted in order to add real-time capabilities to the Linux based control system computers running the Tango software. A software communication protocol based on Gigabit Ethernet and known as Network Reflective Memory (NRM) has been developed to implement a shared memory across the whole control system, allowing computers to communicate in real-time. The NRM architecture, the real-time performance and the integration in the control system are described. (authors)

Real-time monitoring energy efficiency and performance degradation of condensing boilers

International Nuclear Information System (INIS)

Baldi, Simone; Quang, Thuan Le; Holub, Ondrej; Endel, Petr

2017-01-01

Highlights: • Fully-fledged set of fault detection and diagnosis tools for condensing boilers. • Detection of boiler performance degradation in condensing and noncondensing mode. • Virtual sensing for estimation of water mass flow rate. • Optimal Kalman detection of actuator and sensor faults. • Structural properties for detection and isolation of faults. - Abstract: Condensing boilers achieve higher efficiency than traditional boilers by using waste heat in flue gases to preheat cold return water entering the boiler. Water vapor produced during combustion is condensed into liquid form, thus recovering its latent heat of vaporization, leading to around 10–12% increased efficiency. Many countries have encouraged the use of condensing boilers with financial incentives. It is thus important to develop software tools to assess the correct functioning of the boiler and eventually detect problems. Current monitoring tools are based on boiler static maps and on large sets of historical data, and are unable to assess timely loss of performance due to degradation of the efficiency curve or water leakages. This work develops a set of fault detection and diagnosis tools for dynamic energy efficiency monitoring and assessment in condensing boilers, i.e. performance degradation and faults can be detected using real-time measurements: this real-time feature is particularly relevant because of the limited amount of data that can be stored by state-of-the-art building energy management systems. The monitoring tools are organized as follows: a bimodal parameter estimator to detect deviations of the efficiency of the boiler from nominal values in both condensing and noncondensing mode; a virtual sensor for the estimation of the water mass flow rate; filters to detect actuator and sensor faults, possibly due to control and sensing problems. Most importantly, structural properties for detection and isolation of actuators and sensing faults are given: these properties are

Reversal of Dabigatran Using Idarucizumab in a Septic Patient with Impaired Kidney Function in Real-Life Practice

Directory of Open Access Journals (Sweden)

Thomas C. Sauter

2016-01-01

Full Text Available Background. Immediate reversal of anticoagulation is essential when facing severe bleeding or emergency surgery. Although idarucizumab is approved for the reversal of dabigatran in many countries, clinical experiences are lacking, particularly in special patient-populations such as sepsis and impaired renal function. Case Presentation. We present the case of a 67-year-old male septic patient with a multilocular facial abscess and chronic kidney disease (GFR 36.5 mL/min. Thrombin time (TT and activated partial thromboplastin time (aPTT 15 hours after the last intake of 150 mg dabigatran were both prolonged (>120 sec, resp., 61 sec, as well as unbound dabigatran concentration (119.05 ng/mL. Before immediate emergency surgery dabigatran was antagonised using idarucizumab 2 × 2.5 g. Dabigatran concentration was not detectable 10 min after idarucizumab administration (<30 ng/mL. TT and aPTT time were normalised (16.2 sec, resp., 30.2 sec. Sepsis was controlled after surgery and kidney function remained stable. In the absence of postoperative bleeding, dabigatran was restarted 36 hours after admission. Conclusion. Idarucizumab successfully reversed the effect of dabigatran in real-life practice in a patient with sepsis and renal impairment and allowed emergency surgery with normal haemostasis. Efficacy and safety in real-life practice will nevertheless require prospective registries monitoring.

Real-time reverse transcription polymerase chain reaction method for detection of Canine distemper virus modified live vaccine shedding for differentiation from infection with wild-type strains.

Science.gov (United States)

Wilkes, Rebecca P; Sanchez, Elena; Riley, Matthew C; Kennedy, Melissa A

2014-01-01

Canine distemper virus (CDV) remains a common cause of infectious disease in dogs, particularly in high-density housing situations such as shelters. Vaccination of all dogs against CDV is recommended at the time of admission to animal shelters and many use a modified live virus (MLV) vaccine. From a diagnostic standpoint for dogs with suspected CDV infection, this is problematic because highly sensitive diagnostic real-time reverse transcription polymerase chain reaction (RT-PCR) tests are able to detect MLV virus in clinical samples. Real-time PCR can be used to quantitate amount of virus shedding and can differentiate vaccine strains from wild-type strains when shedding is high. However, differentiation by quantitation is not possible in vaccinated animals during acute infection, when shedding is low and could be mistaken for low level vaccine virus shedding. While there are gel-based RT-PCR assays for differentiation of vaccine strains from field strains based on sequence differences, the sensitivity of these assays is unable to match that of the real-time RT-PCR assay currently used in the authors' laboratory. Therefore, a real-time RT-PCR assay was developed that detects CDV MLV vaccine strains and distinguishes them from wild-type strains based on nucleotide sequence differences, rather than the amount of viral RNA in the sample. The test is highly sensitive, with detection of as few as 5 virus genomic copies (corresponding to 10(-1) TCID(50)). Sequencing of the DNA real-time products also allows phylogenetic differentiation of the wild-type strains. This test will aid diagnosis during outbreaks of CDV in recently vaccinated animals.

Digital image processing for real-time neutron radiography and its applications

International Nuclear Information System (INIS)

Fujine, Shigenori

1989-01-01

The present paper describes several digital image processing approaches for the real-time neutron radiography (neutron television-NTV), such as image integration, adaptive smoothing and image enhancement, which have beneficial effects on image improvements, and also describes how to use these techniques for applications. Details invisible in direct images of NTV are able to be revealed by digital image processing, such as reversed image, gray level correction, gray scale transformation, contoured image, subtraction technique, pseudo color display and so on. For real-time application a contouring operation and an averaging approach can also be utilized effectively. (author)

Criticality: static profiling for real-time programs

DEFF Research Database (Denmark)

Brandner, Florian; Hepp, Stefan; Jordan, Alexander

2014-01-01

With the increasing performance demand in real-time systems it becomes more and more important to provide feedback to programmers and software development tools on the performance-relevant code parts of a real-time program. So far, this information was limited to an estimation of the worst....... Experiments using well-established real-time benchmark programs show an interesting distribution of the criticality values, revealing considerable amounts of highly critical as well as uncritical code. The metric thus provides ideal information to programmers and software development tools to optimize...... view covering the entire code base, tools in the spirit of program profiling are required. This work proposes an efficient approach to compute worst-case timing information for all code parts of a program using a complementary metric, called criticality. Every statement of a program is assigned...

Real-Time PCR (qPCR) Primer Design Using Free Online Software

Science.gov (United States)

Thornton, Brenda; Basu, Chhandak

2011-01-01

Real-time PCR (quantitative PCR or qPCR) has become the preferred method for validating results obtained from assays which measure gene expression profiles. The process uses reverse transcription polymerase chain reaction (RT-PCR), coupled with fluorescent chemistry, to measure variations in transcriptome levels between samples. The four most…

Evaluation of Real-Time Performance of the Virtual Seismologist Earthquake Early Warning Algorithm in Switzerland and California

Science.gov (United States)

Behr, Y.; Cua, G. B.; Clinton, J. F.; Heaton, T. H.

2012-12-01

The Virtual Seismologist (VS) method is a Bayesian approach to regional network-based earthquake early warning (EEW) originally formulated by Cua and Heaton (2007). Implementation of VS into real-time EEW codes has been an on-going effort of the Swiss Seismological Service at ETH Zürich since 2006, with support from ETH Zürich, various European projects, and the United States Geological Survey (USGS). VS is one of three EEW algorithms - the other two being ElarmS (Allen and Kanamori, 2003) and On-Site (Wu and Kanamori, 2005; Boese et al., 2008) algorithms - that form the basis of the California Integrated Seismic Network (CISN) ShakeAlert system, a USGS-funded prototype end-to-end EEW system that could potentially be implemented in California. In Europe, VS is currently operating as a real-time test system in Switzerland. As part of the on-going EU project REAKT (Strategies and Tools for Real-Time Earthquake Risk Reduction), VS will be installed and tested at other European networks. VS has been running in real-time on stations of the Southern California Seismic Network (SCSN) since July 2008, and on stations of the Berkeley Digital Seismic Network (BDSN) and the USGS Menlo Park strong motion network in northern California since February 2009. In Switzerland, VS has been running in real-time on stations monitored by the Swiss Seismological Service (including stations from Austria, France, Germany, and Italy) since 2010. We present summaries of the real-time performance of VS in Switzerland and California over the past two and three years respectively. The empirical relationships used by VS to estimate magnitudes and ground motion, originally derived from southern California data, are demonstrated to perform well in northern California and Switzerland. Implementation in real-time and off-line testing in Europe will potentially be extended to southern Italy, western Greece, Istanbul, Romania, and Iceland. Integration of the VS algorithm into both the CISN Advanced

Naphthalocyanine-based time reversal mirror at 800 nm

International Nuclear Information System (INIS)

Galaup, Jean-Pierre; Fraigne, Sebastien; Le Goueet, Jean-Louis; Likforman, Jean-Pierre; Joffre, Manuel

2004-01-01

We performed pulse shaping and time reversal experiments using spectral holography based on persistent spectral hole burning in free-base naphthalocyanine-doped films. The application of a new pulse re-compression scheme based on a programmable hole burning material acting as a time reversal mirror is considered. In this work, we adapted the Fourier transform spectral interferometry technique for measuring the amplitude and phase of photon echo signals produced by diffraction of femtosecond pulses on a spectral hologram. We therefore demonstrated that we could control the pulses diffracted from the hologram by shaping and then characterizing these pulses in both amplitude and phase by spectral interferometry

A Novel Reverse-Transcriptase Real-Time PCR Method for Quantification of Viable Vibrio Parahemolyticus in Raw Shrimp Based on a Rapid Construction of Standard Curve Method

OpenAIRE

Mengtong Jin; Haiquan Liu; Wenshuo Sun; Qin Li; Zhaohuan Zhang; Jibing Li; Yingjie Pan; Yong Zhao

2015-01-01

Vibrio parahemolyticus is an important pathogen that leads to food illness associated seafood. Therefore, rapid and reliable methods to detect and quantify the total viable V. parahaemolyticus in seafood are needed. In this assay, a RNA-based real-time reverse-transcriptase PCR (RT-qPCR) without an enrichment step has been developed for detection and quantification of the total viable V. parahaemolyticus in shrimp. RNA standards with the target segments were synthesized in vitro with T7 RNA p...

Spontaneous breaking of time-reversal symmetry in topological insulators

Energy Technology Data Exchange (ETDEWEB)

Karnaukhov, Igor N., E-mail: karnaui@yahoo.com

2017-06-21

Highlights: • Proposed a new approach for description of phase transitions in topological insulators. • Considered the mechanism of spontaneous breaking of time-reversal symmetry in topological insulators. • The Haldane model can be implemented in real compounds of the condensed matter physics. - Abstract: The system of spinless fermions on a hexagonal lattice is studied. We have considered tight-binding model with the hopping integrals between the nearest-neighbor and next-nearest-neighbor lattice sites, that depend on the direction of the link. The links are divided on three types depending on the direction, the hopping integrals are defined by different phases along the links. The energy of the system depends on the phase differences, the solutions for the phases, that correspond to the minimums of the energy, lead to a topological insulator state with the nontrivial Chern numbers. We have analyzed distinct topological states and phase transitions, the behavior of the chiral gapless edge modes, have defined the Chern numbers. The band structure of topological insulator (TI) is calculated, the ground-state phase diagram in the parameter space is obtained. We propose a novel mechanism of realization of TI, when the TI state is result of spontaneous breaking of time-reversal symmetry due to nontrivial stable solutions for the phases that determine the hopping integrals along the links and show that the Haldane model can be implemented in real compounds of the condensed matter physics.

Harmonizing electricity markets with physics : real time performance monitoring using grid-3PTM

International Nuclear Information System (INIS)

Budhraja, V.S.

2003-01-01

The Electric Power Group, LLC provides management and strategic consulting services for the electric power industry, with special emphasis on industry restructuring, competitive electricity markets, grid operations and reliability, power technologies, venture investments and start-ups. The Consortium for Electric Reliability Technology Solutions involves national laboratories, universities, and industry partners in researching, developing, and commercializing electric reliability technology solutions to protect and enhance the reliability of the American electric power system under the emerging competitive electricity market structure. Physics differentiate electric markets from other markets: there is real-time balancing, no storage, interconnected network, and power flows governed by physics. Some issues affecting both grid reliability and market issues are difficult to separate, such as security and congestion management, voltage management, reserves, frequency volatility, and others. The author examined the following investment challenges facing the electricity market: grid solutions, market solutions, and technology solutions. The real time performance monitoring and prediction platform, grid-3P was described and applications discussed, such as ACE-frequency monitoring, performance monitoring for automatic generation control (AGC) and frequency response, voltage/VAR monitoring, stability monitoring using phasor technology, and market monitoring. figs

Measuring Performance of Soft Real-Time Tasks on Multi-core Systems

OpenAIRE

Rafiq, Salman

2011-01-01

Multi-core platforms are well established, and they are slowly moving into the area of embedded and real-time systems. Nowadays to take advantage of multi-core systems in terms of throughput, soft real-time applications are run together with general purpose applications under an operating system such as Linux. But due to shared hardware resources in multi-core architectures, it is likely that these applications will interfere and compete with each other. This can cause slower response times f...

Impact source identification in finite isotropic plates using a time-reversal method: theoretical study

International Nuclear Information System (INIS)

Chen, Chunlin; Yuan, Fuh-Gwo

2010-01-01

This paper aims to identify impact sources on plate-like structures based on the synthetic time-reversal (T-R) concept using an array of sensors. The impact source characteristics, namely, impact location and impact loading time history, are reconstructed using the invariance of time-reversal concept, reciprocal theory, and signal processing algorithms. Numerical verification for two finite isotropic plates under low and high velocity impacts is performed to demonstrate the versatility of the synthetic T-R method for impact source identification. The results show that the impact location and time history of the impact force with various shapes and frequency bands can be readily obtained with only four sensors distributed around the impact location. The effects of time duration and the inaccuracy in the estimated impact location on the accuracy of the time history of the impact force using the T-R method are investigated. Since the T-R technique retraces all the multi-paths of reflected waves from the geometrical boundaries back to the impact location, it is well suited for quantifying the impact characteristics for complex structures. In addition, this method is robust against noise and it is suggested that a small number of sensors is sufficient to quantify the impact source characteristics through simple computation; thus it holds promise for the development of passive structural health monitoring (SHM) systems for impact monitoring in near real-time

Hybrid monitoring scheme for end-to-end performance enhancement of multicast-based real-time media

Science.gov (United States)

Park, Ju-Won; Kim, JongWon

2004-10-01

As real-time media applications based on IP multicast networks spread widely, end-to-end QoS (quality of service) provisioning for these applications have become very important. To guarantee the end-to-end QoS of multi-party media applications, it is essential to monitor the time-varying status of both network metrics (i.e., delay, jitter and loss) and system metrics (i.e., CPU and memory utilization). In this paper, targeting the multicast-enabled AG (Access Grid) a next-generation group collaboration tool based on multi-party media services, the applicability of hybrid monitoring scheme that combines active and passive monitoring is investigated. The active monitoring measures network-layer metrics (i.e., network condition) with probe packets while the passive monitoring checks both application-layer metrics (i.e., user traffic condition by analyzing RTCP packets) and system metrics. By comparing these hybrid results, we attempt to pinpoint the causes of performance degradation and explore corresponding reactions to improve the end-to-end performance. The experimental results show that the proposed hybrid monitoring can provide useful information to coordinate the performance improvement of multi-party real-time media applications.

Reversible perspective and splitting in time.

Science.gov (United States)

Hart, Helen Schoenhals

2012-01-01

The element of time--the experience of it and the defensive use of it--is explored in conjunction with the use of reversible perspective as a psychotic defense. Clinical material from a long analysis illustrates how a psychotic patient used the reversible perspective, with its static splitting, to abolish the experience of time. When he improved and the reversible perspective became less effective for him, he replaced it with a more dynamic splitting mechanism using time gaps. With further improvement, the patient began to experience the passage of time, and along with it the excruciating pain of separation, envy, and loss.

Real-time simulation of large-scale floods

Science.gov (United States)

Liu, Q.; Qin, Y.; Li, G. D.; Liu, Z.; Cheng, D. J.; Zhao, Y. H.

2016-08-01

According to the complex real-time water situation, the real-time simulation of large-scale floods is very important for flood prevention practice. Model robustness and running efficiency are two critical factors in successful real-time flood simulation. This paper proposed a robust, two-dimensional, shallow water model based on the unstructured Godunov- type finite volume method. A robust wet/dry front method is used to enhance the numerical stability. An adaptive method is proposed to improve the running efficiency. The proposed model is used for large-scale flood simulation on real topography. Results compared to those of MIKE21 show the strong performance of the proposed model.

CODA Performance in the Real World

International Nuclear Information System (INIS)

D.J. Abbott; W.G. Heyes; E. Jastrzembski; R. W. MacLeod; C. Timmer; E. Wolin

2000-01-01

The most ambitious implementation of the Jefferson Lab data acquisition system (CODA) to date is for the CLAS spectrometer in Experimental Hall B. CLAS has over 40,000 instrumented channels and uses up to 30 front-end (FASTBUS/VME) crates in the DAQ subsystem. During the initial experiments we found that performance of the fully instrumented DAQ system did not scale as expected based on single point to point benchmarks. Over the past year we have been able to study various performance bottlenecks in the CLAS DAQ system including front-end real time performance, switched 100BaseT Ethernet data transport, and online data distribution and recording. Performance tuning was necessary for components on both real time (VxWorks) and UNIX (Solaris) operating systems. In addition, a new efficient Event Transfer System (ET) was developed to provide faster online monitoring while having minimal impact on data throughput to storage. We discuss these issues and efforts to overcome the real world problems associated with running a high performance DAQ system on a variety of commercial hardware and software

CODA performance in the real world

International Nuclear Information System (INIS)

Abbott, D.J.; Heyes, W.G.; Jastrzembski, E.; MacLeod, R.W.; Timmer, C.; Wolin, E.

1999-01-01

The most ambitious implementation of the Jefferson Lab data acquisition system (CODA) to date is for the CLAS spectrometer in Experimental Hall B. CLAS has over 40,000 instrumented channels and uses up to 30 front-end (FASTBUS/VME) crates in the DAQ subsystem. During the initial experiments the authors found that performance of the fully instrumented DAQ system did not scale as expected based on single point to point benchmarks. Over the past year the authors have been able to study various performance bottlenecks in the CLAS DAQ system including front-end real time performance, switched 100BaseT Ethernet data transport, and online data distribution and recording. Performance tuning was necessary for components on both real time (VxWorks) and UNIX (Solaris) operating systems. In addition, a new efficient Event Transfer System (ET) was developed to provide faster online monitoring while having minimal impact on data throughput to storage. They discuss these issues and efforts to overcome the real world problems associated with running a high performance DAQ system on a variety of commercial hardware and software

Quantitative evaluation of stone fragments in extracorporeal shock wave lithotripsy using a time reversal operator

Science.gov (United States)

Wang, Jen-Chieh; Zhou, Yufeng

2017-03-01

Extracorporeal shock wave lithotripsy (ESWL) has been used widely in the noninvasive treatment of kidney calculi. The fine fragments less than 2 mm in size can be discharged by urination, which determines the success of ESWL. Although ultrasonic and fluorescent imaging are used to localize the calculi, it's challenging to monitor the stone comminution progress, especially at the late stage of ESWL when fragments spread out as a cloud. The lack of real-time and quantitative evaluation makes this procedure semi-blind, resulting in either under- or over-treatment after the legal number of pulses required by FDA. The time reversal operator (TRO) method has the ability to detect point-like scatterers, and the number of non-zero eigenvalues of TRO is equal to that of the scatterers. In this study, the validation of TRO method to identify stones was illustrated from both numerical and experimental results for one to two stones with various sizes and locations. Furthermore, the parameters affecting the performance of TRO method has also been investigated. Overall, TRO method is effective in identifying the fragments in a stone cluster in real-time. Further development of a detection system and evaluation of its performance both in vitro and in vivo during ESWL is necessary for application.

Evaluation of a duplex reverse-transcription real-time PCR assay for the detection of encephalomyocarditis virus.

Science.gov (United States)

Qin, Shaomin; Underwood, Darren; Driver, Luke; Kistler, Carol; Diallo, Ibrahim; Kirkland, Peter D

2018-06-01

We evaluated a fluorogenic probe-based assay for the detection of encephalomyocarditis virus (EMCV) by comparing a set of published primers and probe to a new set of primers and probe. The published reagents failed to amplify a range of Australian isolates and an Italian reference strain of EMCV. In contrast, an assay based on 2 new sets of primers and probes that were run in a duplex reverse-transcription real-time PCR (RT-rtPCR) worked well, with high amplification efficiency. The analytical sensitivity was ~100-fold higher than virus isolation in cell culture. The intra-assay variation was 0.21-4.90%. No cross-reactivity was observed with a range of other porcine viruses. One hundred and twenty-two clinical specimens were tested simultaneously by RT-rtPCR and virus isolation in cell culture; 72 specimens gave positive results by RT-rtPCR, and 63 of these were also positive by virus isolation. Of 245 archived cell culture isolates of EMCV that were tested in the RT-rtPCR, 242 samples were positive. The new duplex RT-rtPCR assay is a reliable tool for the detection of EMCV in clinical specimens and for use in epidemiologic investigations.

Real-time video quality monitoring

Science.gov (United States)

Liu, Tao; Narvekar, Niranjan; Wang, Beibei; Ding, Ran; Zou, Dekun; Cash, Glenn; Bhagavathy, Sitaram; Bloom, Jeffrey

2011-12-01

The ITU-T Recommendation G.1070 is a standardized opinion model for video telephony applications that uses video bitrate, frame rate, and packet-loss rate to measure the video quality. However, this model was original designed as an offline quality planning tool. It cannot be directly used for quality monitoring since the above three input parameters are not readily available within a network or at the decoder. And there is a great room for the performance improvement of this quality metric. In this article, we present a real-time video quality monitoring solution based on this Recommendation. We first propose a scheme to efficiently estimate the three parameters from video bitstreams, so that it can be used as a real-time video quality monitoring tool. Furthermore, an enhanced algorithm based on the G.1070 model that provides more accurate quality prediction is proposed. Finally, to use this metric in real-world applications, we present an example emerging application of real-time quality measurement to the management of transmitted videos, especially those delivered to mobile devices.

Time reversibility in the quantum frame

Energy Technology Data Exchange (ETDEWEB)

Masot-Conde, Fátima [Escuela Superior Ingenieros, Dpt. Física Aplicada III, Universidad de Sevilla Isla Mágica, 41092- Sevilla (Spain)

2014-12-04

Classic Mechanics and Electromagnetism, conventionally taken as time-reversible, share the same concept of motion (either of mass or charge) as the basis of the time reversibility in their own fields. This paper focuses on the relationship between mobile geometry and motion reversibility. The goal is to extrapolate the conclusions to the quantum frame, where matter and radiation behave just as elementary mobiles. The possibility that the asymmetry of Time (Time’s arrow) is an effect of a fundamental quantum asymmetry of elementary particles, turns out to be a consequence of the discussion.

A digital matched filter for reverse time chaos.

Science.gov (United States)

Bailey, J Phillip; Beal, Aubrey N; Dean, Robert N; Hamilton, Michael C

2016-07-01

The use of reverse time chaos allows the realization of hardware chaotic systems that can operate at speeds equivalent to existing state of the art while requiring significantly less complex circuitry. Matched filter decoding is possible for the reverse time system since it exhibits a closed form solution formed partially by a linear basis pulse. Coefficients have been calculated and are used to realize the matched filter digitally as a finite impulse response filter. Numerical simulations confirm that this correctly implements a matched filter that can be used for detection of the chaotic signal. In addition, the direct form of the filter has been implemented in hardware description language and demonstrates performance in agreement with numerical results.

Real Time Linux - The RTOS for Astronomy?

Science.gov (United States)

Daly, P. N.

The BoF was attended by about 30 participants and a free CD of real time Linux-based upon RedHat 5.2-was available. There was a detailed presentation on the nature of real time Linux and the variants for hard real time: New Mexico Tech's RTL and DIAPM's RTAI. Comparison tables between standard Linux and real time Linux responses to time interval generation and interrupt response latency were presented (see elsewhere in these proceedings). The present recommendations are to use RTL for UP machines running the 2.0.x kernels and RTAI for SMP machines running the 2.2.x kernel. Support, both academically and commercially, is available. Some known limitations were presented and the solutions reported e.g., debugging and hardware support. The features of RTAI (scheduler, fifos, shared memory, semaphores, message queues and RPCs) were described. Typical performance statistics were presented: Pentium-based oneshot tasks running > 30kHz, 486-based oneshot tasks running at ~ 10 kHz, periodic timer tasks running in excess of 90 kHz with average zero jitter peaking to ~ 13 mus (UP) and ~ 30 mus (SMP). Some detail on kernel module programming, including coding examples, were presented showing a typical data acquisition system generating simulated (random) data writing to a shared memory buffer and a fifo buffer to communicate between real time Linux and user space. All coding examples were complete and tested under RTAI v0.6 and the 2.2.12 kernel. Finally, arguments were raised in support of real time Linux: it's open source, free under GPL, enables rapid prototyping, has good support and the ability to have a fully functioning workstation capable of co-existing hard real time performance. The counter weight-the negatives-of lack of platforms (x86 and PowerPC only at present), lack of board support, promiscuous root access and the danger of ignorance of real time programming issues were also discussed. See ftp://orion.tuc.noao.edu/pub/pnd/rtlbof.tgz for the StarOffice overheads

Multiresource allocation and scheduling for periodic soft real-time applications

Science.gov (United States)

Gopalan, Kartik; Chiueh, Tzi-cker

2001-12-01

Real-time applications that utilize multiple system resources, such as CPU, disks, and network links, require coordinated scheduling of these resources in order to meet their end-to-end performance requirements. Most state-of-the-art operating systems support independent resource allocation and deadline-driven scheduling but lack coordination among multiple heterogeneous resources. This paper describes the design and implementation of an Integrated Real-time Resource Scheduler (IRS) that performs coordinated allocation and scheduling of multiple heterogeneous resources on the same machine for periodic soft real-time application. The principal feature of IRS is a heuristic multi-resource allocation algorithm that reserves multiple resources for real-time applications in a manner that can maximize the number of applications admitted into the system in the long run. At run-time, a global scheduler dispatches the tasks of the soft real-time application to individual resource schedulers according to the precedence constraints between tasks. The individual resource schedulers, which could be any deadline based schedulers, can make scheduling decisions locally and yet collectively satisfy a real-time application's performance requirements. The tightness of overall timing guarantees is ultimately determined by the properties of individual resource schedulers. However, IRS maximizes overall system resource utilization efficiency by coordinating deadline assignment across multiple tasks in a soft real-time application.

Real-time Avatar Animation from a Single Image.

Science.gov (United States)

Saragih, Jason M; Lucey, Simon; Cohn, Jeffrey F

2011-01-01

A real time facial puppetry system is presented. Compared with existing systems, the proposed method requires no special hardware, runs in real time (23 frames-per-second), and requires only a single image of the avatar and user. The user's facial expression is captured through a real-time 3D non-rigid tracking system. Expression transfer is achieved by combining a generic expression model with synthetically generated examples that better capture person specific characteristics. Performance of the system is evaluated on avatars of real people as well as masks and cartoon characters.

High Performance Embedded System for Real-Time Pattern Matching

CERN Document Server

Sotiropoulou, Calliope Louisa; The ATLAS collaboration; Gkaitatzis, Stamatios; Citraro, Saverio; Giannetti, Paola; Dell'Orso, Mauro

2016-01-01

In this paper we present an innovative and high performance embedded system for real-time pattern matching. This system is based on the evolution of hardware and algorithms developed for the field of High Energy Physics (HEP) and more specifically for the execution of extremely fast pattern matching for tracking of particles produced by proton-proton collisions in hadron collider experiments. A miniaturised version of this complex system is being developed for pattern matching in generic image processing applications. The system works as a contour identifier able to extract the salient features of an image. It is based on the principles of cognitive image processing, which means that it executes fast pattern matching and data reduction mimicking the operation of the human brain. The pattern matching can be executed by a custom designed Associative Memory (AM) chip. The reference patterns are chosen by a complex training algorithm implemented on an FPGA device. Post processing algorithms (e.g. pixel clustering...

Failure analysis of real-time systems

International Nuclear Information System (INIS)

Jalashgar, A.; Stoelen, K.

1998-01-01

This paper highlights essential aspects of real-time software systems that are strongly related to the failures and their course of propagation. The significant influence of means-oriented and goal-oriented system views in the description, understanding and analysing of those aspects is elaborated. The importance of performing failure analysis prior to reliability analysis of real-time systems is equally addressed. Problems of software reliability growth models taking the properties of such systems into account are discussed. Finally, the paper presents a preliminary study of a goal-oriented approach to model the static and dynamic characteristics of real-time systems, so that the corresponding analysis can be based on a more descriptive and informative picture of failures, their effects and the possibility of their occurrence. (author)

A high performance load balance strategy for real-time multicore systems.

Science.gov (United States)

Cho, Keng-Mao; Tsai, Chun-Wei; Chiu, Yi-Shiuan; Yang, Chu-Sing

2014-01-01

Finding ways to distribute workloads to each processor core and efficiently reduce power consumption is of vital importance, especially for real-time systems. In this paper, a novel scheduling algorithm is proposed for real-time multicore systems to balance the computation loads and save power. The developed algorithm simultaneously considers multiple criteria, a novel factor, and task deadline, and is called power and deadline-aware multicore scheduling (PDAMS). Experiment results show that the proposed algorithm can greatly reduce energy consumption by up to 54.2% and the deadline times missed, as compared to the other scheduling algorithms outlined in this paper.

Prototyping Real-Time Control in the SPS

CERN Document Server

Andersson, J; Jensen, L; Jones, R; Lamont, M; Wenninger, J; Wijnands, Thijs; CERN. Geneva. AB Department

2003-01-01

Real-time control of beam related parameters will be required in the LHC. In order to gain experience of the issues involved in implementing distributed real-time control over large distances, a prototype local orbit feedback system is being developed in the SPS. This will use 6 pickups, each equipped with the full LHC acquisition electronics chain and linked to a real-time communication and feedback system. This reports summarises the .rst tests performed with this system in October 2002, where the data from four pickups was successfully acquired and displayed at 10 Hz in the control room.

Formal methods for dependable real-time systems

Science.gov (United States)

Rushby, John

1993-01-01

The motivation for using formal methods to specify and reason about real time properties is outlined and approaches that were proposed and used are sketched. The formal verifications of clock synchronization algorithms are concluded as showing that mechanically supported reasoning about complex real time behavior is feasible. However, there was significant increase in the effectiveness of verification systems since those verifications were performed, at it is to be expected that verifications of comparable difficulty will become fairly routine. The current challenge lies in developing perspicuous and economical approaches to the formalization and specification of real time properties.

Real-time simulation of a Doubly-Fed Induction Generator based wind power system on eMEGASimRTM Real-Time Digital Simulator

Science.gov (United States)

Boakye-Boateng, Nasir Abdulai

The growing demand for wind power integration into the generation mix prompts the need to subject these systems to stringent performance requirements. This study sought to identify the required tools and procedures needed to perform real-time simulation studies of Doubly-Fed Induction Generator (DFIG) based wind generation systems as basis for performing more practical tests of reliability and performance for both grid-connected and islanded wind generation systems. The author focused on developing a platform for wind generation studies and in addition, the author tested the performance of two DFIG models on the platform real-time simulation model; an average SimpowerSystemsRTM DFIG wind turbine, and a detailed DFIG based wind turbine using ARTEMiSRTM components. The platform model implemented here consists of a high voltage transmission system with four integrated wind farm models consisting in total of 65 DFIG based wind turbines and it was developed and tested on OPAL-RT's eMEGASimRTM Real-Time Digital Simulator.

Real-time UNIX in HEP data acquisition

International Nuclear Information System (INIS)

Buono, S.; Gaponenko, I.; Jones, R.; Mapelli, L.; Mornacchi, G.; Prigent, D.; Sanchez-Corral, E.; Skiadelli, M.; Toppers, A.; Duval, P.Y.; Ferrato, D.; Le Van Suu, A.; Qian, Z.; Rondot, C.; Ambrosini, G.; Fumagalli, G.; Aguer, M.; Huet, M.

1994-01-01

Today's experimentation in high energy physics is characterized by an increasing need for sensitivity to rare phenomena and complex physics signatures, which require the use of huge and sophisticated detectors and consequently a high performance readout and data acquisition. Multi-level triggering, hierarchical data collection and an always increasing amount of processing power, distributed throughout the data acquisition layers, will impose a number of features on the software environment, especially the need for a high level of standardization. Real-time UNIX seems, today, the best solution for the platform independence, operating system interface standards and real-time features necessary for data acquisition in HEP experiments. We present the results of the evaluation, in a realistic application environment, of a Real-Time UNIX operating system: the EP/LX real-time UNIX system. ((orig.))

The Implementation of a Real-Time Polyphase Filter

OpenAIRE

Adámek, Karel; Novotný, Jan; Armour, Wes

2014-01-01

In this article we study the suitability of dierent computational accelerators for the task of real-time data processing. The algorithm used for comparison is the polyphase filter, a standard tool in signal processing and a well established algorithm. We measure performance in FLOPs and execution time, which is a critical factor for real-time systems. For our real-time studies we have chosen a data rate of 6.5GB/s, which is the estimated data rate for a single channel on the SKAs Low Frequenc...

Real-Time Incompressible Fluid Simulation on the GPU

Directory of Open Access Journals (Sweden)

Xiao Nie

2015-01-01

Full Text Available We present a parallel framework for simulating incompressible fluids with predictive-corrective incompressible smoothed particle hydrodynamics (PCISPH on the GPU in real time. To this end, we propose an efficient GPU streaming pipeline to map the entire computational task onto the GPU, fully exploiting the massive computational power of state-of-the-art GPUs. In PCISPH-based simulations, neighbor search is the major performance obstacle because this process is performed several times at each time step. To eliminate this bottleneck, an efficient parallel sorting method for this time-consuming step is introduced. Moreover, we discuss several optimization techniques including using fast on-chip shared memory to avoid global memory bandwidth limitations and thus further improve performance on modern GPU hardware. With our framework, the realism of real-time fluid simulation is significantly improved since our method enforces incompressibility constraint which is typically ignored due to efficiency reason in previous GPU-based SPH methods. The performance results illustrate that our approach can efficiently simulate realistic incompressible fluid in real time and results in a speed-up factor of up to 23 on a high-end NVIDIA GPU in comparison to single-threaded CPU-based implementation.

Evaluation of the PrimerDesign™ genesig real-time reverse transcription-polymerase chain reaction assay and the INFINITI® Respiratory Viral Panel Plus assay for the detection of human metapneumovirus in Kuwait.

Science.gov (United States)

Al-Turab, Mariam; Chehadeh, Wassim; Al-Mulla, Fahd; Al-Nakib, Widad

2012-04-01

Human metapneumovirus (hMPV) is a respiratory pathogen that was discovered in 2001 and is considered a major cause of both upper and lower respiratory tract infections. A sensitive, fast, and high-throughput diagnostic test is needed for the detection of hMPV that may assist in the clinical management as well as in the reduction of inappropriate therapy. Therefore, a comparison assessment was performed in this study between the PrimerDesign™ genesig real-time reverse transcription-polymerase chain reaction (RT-PCR) Assay and the INFINITI(®) Respiratory Viral Panel Plus Assay (RVP-Plus) for the detection of hMPV infection in patients with respiratory tract infections. A total of 200 respiratory samples were collected from 185 hospitalized patients, during the winter season in Kuwait. Of 185 patients, 10 (5.4%) were positive for hMPV RNA by the in-house RT-PCR assay, while 7 (4%) were positive for hMPV RNA by the real-time RT-PCR assay and 9 (5%) were positive for hMPV RNA by the INFINITI(®) RVP-Plus assay. The high incidence rate (60%) of hMPV infection was in January 2011. The sensitivity of the real-time RT-PCR and INFINITI(®) RVP-Plus assays was 70% and 90%, respectively, with specificity of 100% for both assays. hMPV types A and B could be identified in this study; however, discordant genotyping results were found between the direct sequencing method and the INFINITI(®) RVP-Plus assay in 33% of hMPV-positive patients. Copyright © 2012 Elsevier Inc. All rights reserved.

A New Generation of Real-Time Systems in the JET Tokamak

Science.gov (United States)

Alves, Diogo; Neto, Andre C.; Valcarcel, Daniel F.; Felton, Robert; Lopez, Juan M.; Barbalace, Antonio; Boncagni, Luca; Card, Peter; De Tommasi, Gianmaria; Goodyear, Alex; Jachmich, Stefan; Lomas, Peter J.; Maviglia, Francesco; McCullen, Paul; Murari, Andrea; Rainford, Mark; Reux, Cedric; Rimini, Fernanda; Sartori, Filippo; Stephen, Adam V.; Vega, Jesus; Vitelli, Riccardo; Zabeo, Luca; Zastrow, Klaus-Dieter

2014-04-01

Recently, a new recipe for developing and deploying real-time systems has become increasingly adopted in the JET tokamak. Powered by the advent of x86 multi-core technology and the reliability of JET's well established Real-Time Data Network (RTDN) to handle all real-time I/O, an official Linux vanilla kernel has been demonstrated to be able to provide real-time performance to user-space applications that are required to meet stringent timing constraints. In particular, a careful rearrangement of the Interrupt ReQuests' (IRQs) affinities together with the kernel's CPU isolation mechanism allows one to obtain either soft or hard real-time behavior depending on the synchronization mechanism adopted. Finally, the Multithreaded Application Real-Time executor (MARTe) framework is used for building applications particularly optimised for exploring multi-core architectures. In the past year, four new systems based on this philosophy have been installed and are now part of JET's routine operation. The focus of the present work is on the configuration aspects that enable these new systems' real-time capability. Details are given about the common real-time configuration of these systems, followed by a brief description of each system together with results regarding their real-time performance. A cycle time jitter analysis of a user-space MARTe based application synchronizing over a network is also presented. The goal is to compare its deterministic performance while running on a vanilla and on a Messaging Real time Grid (MRG) Linux kernel.

Confabulation Based Real-time Anomaly Detection for Wide-area Surveillance Using Heterogeneous High Performance Computing Architecture

Science.gov (United States)

2015-06-01

CONFABULATION BASED REAL-TIME ANOMALY DETECTION FOR WIDE-AREA SURVEILLANCE USING HETEROGENEOUS HIGH PERFORMANCE COMPUTING ARCHITECTURE SYRACUSE...DETECTION FOR WIDE-AREA SURVEILLANCE USING HETEROGENEOUS HIGH PERFORMANCE COMPUTING ARCHITECTURE 5a. CONTRACT NUMBER FA8750-12-1-0251 5b. GRANT...processors including graphic processor units (GPUs) and Intel Xeon Phi processors. Experimental results showed significant speedups, which can enable

Research and Realization of the HJ-1C Real-time Software Frame Synchronization Algorithm

OpenAIRE

Hou Yang-shuan; Shi Tao; Hu Yu-xin

2014-01-01

Conventional software frame synchronization methods are inefficient in processing huge continuous data without synchronization words. To improve the processing speed, a real-time synchronization algorithm is proposed based on reverse searching. Satellite data are grouped and searched in the reverse direction to avoid searching for synchronization words in huge continuous invalid data; thus, the frame synchronization speed is improved enormously. The fastest processing speed is up to 15445.9 M...

Hard Real-Time Linux for Off-The-Shelf Multicore Architectures

OpenAIRE

Radder, Dirk

2015-01-01

This document describes the research results that were obtained from the development of a real-time extension for the Linux operating system. The paper describes a full extension of the kernel, which enables hard real-time performance on a 64-bit x86 architecture. In the first part of this study, real-time systems are categorized and concepts of real-time operating systems are introduced to the reader. In addition, numerous well-known real-time operating systems are considered. QNX Neutrino, ...

Performance analysis and kernel size study of the Lynx real-time operating system

Science.gov (United States)

Liu, Yuan-Kwei; Gibson, James S.; Fernquist, Alan R.

1993-01-01

This paper analyzes the Lynx real-time operating system (LynxOS), which has been selected as the operating system for the Space Station Freedom Data Management System (DMS). The features of LynxOS are compared to other Unix-based operating system (OS). The tools for measuring the performance of LynxOS, which include a high-speed digital timer/counter board, a device driver program, and an application program, are analyzed. The timings for interrupt response, process creation and deletion, threads, semaphores, shared memory, and signals are measured. The memory size of the DMS Embedded Data Processor (EDP) is limited. Besides, virtual memory is not suitable for real-time applications because page swap timing may not be deterministic. Therefore, the DMS software, including LynxOS, has to fit in the main memory of an EDP. To reduce the LynxOS kernel size, the following steps are taken: analyzing the factors that influence the kernel size; identifying the modules of LynxOS that may not be needed in an EDP; adjusting the system parameters of LynxOS; reconfiguring the device drivers used in the LynxOS; and analyzing the symbol table. The reductions in kernel disk size, kernel memory size and total kernel size reduction from each step mentioned above are listed and analyzed.

Recent achievements in real-time computational seismology in Taiwan

Science.gov (United States)

Lee, S.; Liang, W.; Huang, B.

2012-12-01

Real-time computational seismology is currently possible to be achieved which needs highly connection between seismic database and high performance computing. We have developed a real-time moment tensor monitoring system (RMT) by using continuous BATS records and moment tensor inversion (CMT) technique. The real-time online earthquake simulation service is also ready to open for researchers and public earthquake science education (ROS). Combine RMT with ROS, the earthquake report based on computational seismology can provide within 5 minutes after an earthquake occurred (RMT obtains point source information ROS completes a 3D simulation real-time now. For more information, welcome to visit real-time computational seismology earthquake report webpage (RCS).

A High Performance Load Balance Strategy for Real-Time Multicore Systems

Directory of Open Access Journals (Sweden)

Keng-Mao Cho

2014-01-01

Full Text Available Finding ways to distribute workloads to each processor core and efficiently reduce power consumption is of vital importance, especially for real-time systems. In this paper, a novel scheduling algorithm is proposed for real-time multicore systems to balance the computation loads and save power. The developed algorithm simultaneously considers multiple criteria, a novel factor, and task deadline, and is called power and deadline-aware multicore scheduling (PDAMS. Experiment results show that the proposed algorithm can greatly reduce energy consumption by up to 54.2% and the deadline times missed, as compared to the other scheduling algorithms outlined in this paper.

Effects of computing time delay on real-time control systems

Science.gov (United States)

Shin, Kang G.; Cui, Xianzhong

1988-01-01

The reliability of a real-time digital control system depends not only on the reliability of the hardware and software used, but also on the speed in executing control algorithms. The latter is due to the negative effects of computing time delay on control system performance. For a given sampling interval, the effects of computing time delay are classified into the delay problem and the loss problem. Analysis of these two problems is presented as a means of evaluating real-time control systems. As an example, both the self-tuning predicted (STP) control and Proportional-Integral-Derivative (PID) control are applied to the problem of tracking robot trajectories, and their respective effects of computing time delay on control performance are comparatively evaluated. For this example, the STP (PID) controller is shown to outperform the PID (STP) controller in coping with the delay (loss) problem.

Real-time computational photon-counting LiDAR

Science.gov (United States)

Edgar, Matthew; Johnson, Steven; Phillips, David; Padgett, Miles

2018-03-01

The availability of compact, low-cost, and high-speed MEMS-based spatial light modulators has generated widespread interest in alternative sampling strategies for imaging systems utilizing single-pixel detectors. The development of compressed sensing schemes for real-time computational imaging may have promising commercial applications for high-performance detectors, where the availability of focal plane arrays is expensive or otherwise limited. We discuss the research and development of a prototype light detection and ranging (LiDAR) system via direct time of flight, which utilizes a single high-sensitivity photon-counting detector and fast-timing electronics to recover millimeter accuracy three-dimensional images in real time. The development of low-cost real time computational LiDAR systems could have importance for applications in security, defense, and autonomous vehicles.

Constraints on a parity-even/time-reversal-odd interaction

International Nuclear Information System (INIS)

Oers, Willem T.H. van

2000-01-01

Time-Reversal-Invariance non-conservation has for the first time been unequivocally demonstrated in a direct measurement, one of the results of the CPLEAR experiment. What is the situation then with regard to time-reversal-invariance non-conservation in systems other than the neutral kaon system? Two classes of tests of time-reversal-invariance need to be distinguished: the first one deals with parity violating (P-odd)/time-reversal-invariance non-conserving (T-odd) interactions, while the second one deals with P-even/T-odd interactions (assuming CPT conservation this implies C-conjugation non-conservation). Limits on a P-odd/T-odd interaction follow from measurements of the electric dipole moment of the neutron. This in turn provides a limit on a P-odd/T-odd pion-nucleon coupling constant which is 10 -4 times the weak interaction strength. Limits on a P-even/T-odd interaction are much less stringent. The better constraint stems also from the measurement of the electric dipole moment of the neutron. Of all the other tests, measurements of charge-symmetry breaking in neutron-proton elastic scattering provide the next better constraint. The latter experiments were performed at TRIUMF (at 477 and 347 MeV) and at IUCF (at 183 MeV). Weak decay experiments (the transverse polarization of the muon in K + →π 0 μ + ν μ and the transverse polarization of the positrons in polarized muon decay) have the potential to provide comparable or possibly better constraints

Time-reversal symmetry breaking in quantum billiards

Energy Technology Data Exchange (ETDEWEB)

Schaefer, Florian

2009-01-26

The present doctoral thesis describes experimentally measured properties of the resonance spectra of flat microwave billiards with partially broken timereversal invariance induced by an embedded magnetized ferrite. A vector network analyzer determines the complex scattering matrix elements. The data is interpreted in terms of the scattering formalism developed in nuclear physics. At low excitation frequencies the scattering matrix displays isolated resonances. At these the effect of the ferrite on isolated resonances (singlets) and pairs of nearly degenerate resonances (doublets) is investigated. The hallmark of time-reversal symmetry breaking is the violation of reciprocity, i.e. of the symmetry of the scattering matrix. One finds that reciprocity holds in singlets; it is violated in doublets. This is modeled by an effective Hamiltonian of the resonator. A comparison of the model to the data yields time-reversal symmetry breaking matrix elements in the order of the level spacing. Their dependence on the magnetization of the ferrite is understood in terms of its magnetic properties. At higher excitation frequencies the resonances overlap and the scattering matrix elements fluctuate irregularly (Ericson fluctuations). They are analyzed in terms of correlation functions. The data are compared to three models based on random matrix theory. The model by Verbaarschot, Weidenmueller and Zirnbauer describes time-reversal invariant scattering processes. The one by Fyodorov, Savin and Sommers achieves the same for systems with complete time-reversal symmetry breaking. An extended model has been developed that accounts for partial breaking of time-reversal invariance. This extended model is in general agreement with the data, while the applicability of the other two models is limited. The cross-correlation function between forward and backward reactions determines the time-reversal symmetry breaking matrix elements of the Hamiltonian to up to 0.3 mean level spacings. Finally

Time-reversal symmetry breaking in quantum billiards

International Nuclear Information System (INIS)

Schaefer, Florian

2009-01-01

The present doctoral thesis describes experimentally measured properties of the resonance spectra of flat microwave billiards with partially broken timereversal invariance induced by an embedded magnetized ferrite. A vector network analyzer determines the complex scattering matrix elements. The data is interpreted in terms of the scattering formalism developed in nuclear physics. At low excitation frequencies the scattering matrix displays isolated resonances. At these the effect of the ferrite on isolated resonances (singlets) and pairs of nearly degenerate resonances (doublets) is investigated. The hallmark of time-reversal symmetry breaking is the violation of reciprocity, i.e. of the symmetry of the scattering matrix. One finds that reciprocity holds in singlets; it is violated in doublets. This is modeled by an effective Hamiltonian of the resonator. A comparison of the model to the data yields time-reversal symmetry breaking matrix elements in the order of the level spacing. Their dependence on the magnetization of the ferrite is understood in terms of its magnetic properties. At higher excitation frequencies the resonances overlap and the scattering matrix elements fluctuate irregularly (Ericson fluctuations). They are analyzed in terms of correlation functions. The data are compared to three models based on random matrix theory. The model by Verbaarschot, Weidenmueller and Zirnbauer describes time-reversal invariant scattering processes. The one by Fyodorov, Savin and Sommers achieves the same for systems with complete time-reversal symmetry breaking. An extended model has been developed that accounts for partial breaking of time-reversal invariance. This extended model is in general agreement with the data, while the applicability of the other two models is limited. The cross-correlation function between forward and backward reactions determines the time-reversal symmetry breaking matrix elements of the Hamiltonian to up to 0.3 mean level spacings. Finally

Reference genes for gene expression analysis by real-time reverse transcription polymerase chain reaction of renal cell carcinoma.

Science.gov (United States)

Bjerregaard, Henriette; Pedersen, Shona; Kristensen, Søren Risom; Marcussen, Niels

2011-12-01

Differentiation between malignant renal cell carcinoma and benign oncocytoma is of great importance to choose the optimal treatment. Accurate preoperative diagnosis of renal tumor is therefore crucial; however, existing imaging techniques and histologic examinations are incapable of providing an optimal differentiation profile. Analysis of gene expression of molecular markers is a new possibility but relies on appropriate standardization to compare different samples. The aim of this study was to identify stably expressed reference genes suitable for the normalization of results extracted from gene expression analysis of renal tumors. Expression levels of 8 potential reference genes (ATP5J, HMBS, HPRT1, PPIA, TBP, 18S, GAPDH, and POLR2A) were examined by real-time reverse transcription polymerase chain reaction in tumor and normal tissue from removed kidneys from 13 patients with renal cell carcinoma and 5 patients with oncocytoma. The expression levels of genes were compared by gene stability value M, average gene stability M, pairwise variation V, and coefficient of variation CV. More candidates were not suitable for the purpose, but a combination of HMBS, PPIA, ATP5J, and TBP was found to be the best combination with an average gene stability value M of 0.9 and a CV of 0.4 in the 18 tumors and normal tissues. A combination of 4 genes, HMBS, PPIA, ATP5J, and TBP, is a possible reference in renal tumor gene expression analysis by reverse transcription polymerase chain reaction. A combination of four genes, HMBS, PPIA, ATP5J and TBP, being stably expressed in tissues from RCC is possible reference genes for gene expression analysis.

Diffusive real-time dynamics of a particle with Berry curvature

Science.gov (United States)

Misaki, Kou; Miyashita, Seiji; Nagaosa, Naoto

2018-02-01

We study theoretically the influence of Berry phase on the real-time dynamics of the single particle focusing on the diffusive dynamics, i.e., the time dependence of the distribution function. Our model can be applied to the real-time dynamics of intraband relaxation and diffusion of optically excited excitons, trions, or particle-hole pair. We found that the dynamics at the early stage is deeply influenced by the Berry curvature in real space (B ), momentum space (Ω ), and also the crossed space between these two (C ). For example, it is found that Ω induces the rotation of the wave packet and causes the time dependence of the mean square displacement of the particle to be linear in time t at the initial stage; it is qualitatively different from the t3 dependence in the absence of the Berry curvature. It is also found that Ω and C modify the characteristic time scale of the thermal equilibration of momentum distribution. Moreover, the dynamics under various combinations of B ,Ω , and C shows singular behaviors such as the critical slowing down or speeding up of the momentum equilibration and the reversals of the direction of rotations. The relevance of our model for time-resolved experiments in transition metal dichalcogenides is also discussed.

Quantitative (real-time) PCR

International Nuclear Information System (INIS)

Denman, S.E.; McSweeney, C.S.

2005-01-01

Many nucleic acid-based probe and PCR assays have been developed for the detection tracking of specific microbes within the rumen ecosystem. Conventional PCR assays detect PCR products at the end stage of each PCR reaction, where exponential amplification is no longer being achieved. This approach can result in different end product (amplicon) quantities being generated. In contrast, using quantitative, or real-time PCR, quantification of the amplicon is performed not at the end of the reaction, but rather during exponential amplification, where theoretically each cycle will result in a doubling of product being created. For real-time PCR, the cycle at which fluorescence is deemed to be detectable above the background during the exponential phase is termed the cycle threshold (Ct). The Ct values obtained are then used for quantitation, which will be discussed later

Real-time shadows

CERN Document Server

Eisemann, Elmar; Assarsson, Ulf; Wimmer, Michael

2011-01-01

Important elements of games, movies, and other computer-generated content, shadows are crucial for enhancing realism and providing important visual cues. In recent years, there have been notable improvements in visual quality and speed, making high-quality realistic real-time shadows a reachable goal. Real-Time Shadows is a comprehensive guide to the theory and practice of real-time shadow techniques. It covers a large variety of different effects, including hard, soft, volumetric, and semi-transparent shadows.The book explains the basics as well as many advanced aspects related to the domain

Dependable Real-Time Systems

Science.gov (United States)

1991-09-30

0196 or 413 545-0720 PI E-mail Address: krithi@nirvan.cs.umass.edu, stankovic(ocs.umass.edu Grant or Contract Title: Dependable Real - Time Systems Grant...Dependable Real - Time Systems " Grant or Contract Number: N00014-85-k-0398 L " Reporting Period: 1 Oct 87 - 30 Sep 91 , 2. Summary of Accomplishments ’ 2.1 Our...in developing a sound approach to scheduling tasks in complex real - time systems , (2) developed a real-time operating system kernel, a preliminary

A Stack Cache for Real-Time Systems

DEFF Research Database (Denmark)

Schoeberl, Martin; Nielsen, Carsten

2016-01-01

Real-time systems need time-predictable computing platforms to allowfor static analysis of the worst-case execution time. Caches are important for good performance, but data caches arehard to analyze for the worst-case execution time. Stack allocated data has different properties related...

LabVIEW Real-Time

CERN Multimedia

CERN. Geneva; Flockhart, Ronald Bruce; Seppey, P

2003-01-01

With LabVIEW Real-Time, you can choose from a variety of RT Series hardware. Add a real-time data acquisition component into a larger measurement and automation system or create a single stand-alone real-time solution with data acquisition, signal conditioning, motion control, RS-232, GPIB instrumentation, and Ethernet connectivity. With the various hardware options, you can create a system to meet your precise needs today, while the modularity of the system means you can add to the solution as your system requirements grow. If you are interested in Reliable and Deterministic systems for Measurement and Automation, you will profit from this seminar. Agenda: Real-Time Overview LabVIEW RT Hardware Platforms - Linux on PXI Programming with LabVIEW RT Real-Time Operating Systems concepts Timing Applications Data Transfer

Performance Characterization of a Real-Time Massive MIMO System with LOS Mobile Channels

OpenAIRE

Harris, Paul; Malkowsky, Steffen; Vieira, Joao; Hassan, Fredrik Tufvesson Wael Boukley; Liu, Liang; Beach, Mark; Armour, Simon; Edfors, Ove

2017-01-01

The first measured results for massive multiple input, multiple-output (MIMO) performance in a line-of-sight (LOS) scenario with moderate mobility are presented, with 8 users served in real-time using a 100 antenna base Station (BS) at 3.7 GHz. When such a large number of channels dynamically change, the inherent propagation and processing delay has a critical relationship with the rate of change, as the use of outdated channel information can result in severe detection and precoding inaccura...

Exogenous reference gene normalization for real-time reverse transcription-polymerase chain reaction analysis under dynamic endogenous transcription.

Science.gov (United States)

Johnston, Stephen; Gallaher, Zachary; Czaja, Krzysztof

2012-05-15

Quantitative real-time reverse transcription-polymerase chain reaction (qPCR) is widely used to investigate transcriptional changes following experimental manipulations to the nervous system. Despite the widespread utilization of qPCR, the interpretation of results is marred by the lack of a suitable reference gene due to the dynamic nature of endogenous transcription. To address this inherent deficiency, we investigated the use of an exogenous spike-in mRNA, luciferase, as an internal reference gene for the 2(-∆∆Ct) normalization method. To induce dynamic transcription, we systemically administered capsaicin, a neurotoxin selective for C-type sensory neurons expressing the TRPV-1 receptor, to adult male Sprague-Dawley rats. We later isolated nodose ganglia for qPCR analysis with the reference being either exogenous luciferase mRNA or the commonly used endogenous reference β-III tubulin. The exogenous luciferase mRNA reference clearly demonstrated the dynamic expression of the endogenous reference. Furthermore, variability of the endogenous reference would lead to misinterpretation of other genes of interest. In conclusion, traditional reference genes are often unstable under physiologically normal situations, and certainly unstable following the damage to the nervous system. The use of exogenous spike-in reference provides a consistent and easily implemented alternative for the analysis of qPCR data.

Plane-wave Least-squares Reverse Time Migration

KAUST Repository

Dai, Wei

2012-11-04

Least-squares reverse time migration is formulated with a new parameterization, where the migration image of each shot is updated separately and a prestack image is produced with common image gathers. The advantage is that it can offer stable convergence for least-squares migration even when the migration velocity is not completely accurate. To significantly reduce computation cost, linear phase shift encoding is applied to hundreds of shot gathers to produce dozens of planes waves. A regularization term which penalizes the image difference between nearby angles are used to keep the prestack image consistent through all the angles. Numerical tests on a marine dataset is performed to illustrate the advantages of least-squares reverse time migration in the plane-wave domain. Through iterations of least-squares migration, the migration artifacts are reduced and the image resolution is improved. Empirical results suggest that the LSRTM in plane wave domain is an efficient method to improve the image quality and produce common image gathers.

Concepts of real time and semi-real time material control

International Nuclear Information System (INIS)

Lovett, J.E.

1975-01-01

After a brief consideration of the traditional material balance accounting on an MBA basis, this paper explores the basic concepts of real time and semi-real time material control, together with some of the major problems to be solved. Three types of short-term material control are discussed: storage, batch processing, and continuous processing. (DLC)

"Internet of Things" Real-Time Free Flap Monitoring.

Science.gov (United States)

Kim, Sang Hun; Shin, Ho Seong; Lee, Sang Hwan

2018-01-01

Free flaps are a common treatment option for head and neck reconstruction in plastic reconstructive surgery, and monitoring of the free flap is the most important factor for flap survival. In this study, the authors performed real-time free flap monitoring based on an implanted Doppler system and "internet of things" (IoT)/wireless Wi-Fi, which is a convenient, accurate, and efficient approach for surgeons to monitor a free flap. Implanted Doppler signals were checked continuously until the patient was discharged by the surgeon and residents using their own cellular phone or personal computer. If the surgeon decided that a revision procedure or exploration was required, the authors checked the consumed time (positive signal-to-operating room time) from the first notification when the flap's status was questioned to the determination for revision surgery according to a chart review. To compare the efficacy of real-time monitoring, the authors paired the same number of free flaps performed by the same surgeon and monitored the flaps using conventional methods such as a physical examination. The total survival rate was greater in the real-time monitoring group (94.7% versus 89.5%). The average time for the real-time monitoring group was shorter than that for the conventional group (65 minutes versus 86 minutes). Based on this study, real-time free flap monitoring using IoT technology is a method that surgeon and reconstruction team can monitor simultaneously at any time in any situation.

Real Time Systems

DEFF Research Database (Denmark)

Christensen, Knud Smed

2000-01-01

Describes fundamentals of parallel programming and a kernel for that. Describes methods for modelling and checking parallel problems. Real time problems.......Describes fundamentals of parallel programming and a kernel for that. Describes methods for modelling and checking parallel problems. Real time problems....

Real time expert systems

International Nuclear Information System (INIS)

Asami, Tohru; Hashimoto, Kazuo; Yamamoto, Seiichi

1992-01-01

Recently, aiming at the application to the plant control for nuclear reactors and traffic and communication control, the research and the practical use of the expert system suitable to real time processing have become conspicuous. In this report, the condition for the required function to control the object that dynamically changes within a limited time is presented, and the technical difference between the real time expert system developed so as to satisfy it and the expert system of conventional type is explained with the actual examples and from theoretical aspect. The expert system of conventional type has the technical base in the problem-solving equipment originating in STRIPS. The real time expert system is applied to the fields accompanied by surveillance and control, to which conventional expert system is hard to be applied. The requirement for the real time expert system, the example of the real time expert system, and as the techniques of realizing real time processing, the realization of interruption processing, dispersion processing, and the mechanism of maintaining the consistency of knowledge are explained. (K.I.)

Building flexible real-time systems using the Flex language

Science.gov (United States)

Kenny, Kevin B.; Lin, Kwei-Jay

1991-01-01

The design and implementation of a real-time programming language called Flex, which is a derivative of C++, are presented. It is shown how different types of timing requirements might be expressed and enforced in Flex, how they might be fulfilled in a flexible way using different program models, and how the programming environment can help in making binding and scheduling decisions. The timing constraint primitives in Flex are easy to use yet powerful enough to define both independent and relative timing constraints. Program models like imprecise computation and performance polymorphism can carry out flexible real-time programs. In addition, programmers can use a performance measurement tool that produces statistically correct timing models to predict the expected execution time of a program and to help make binding decisions. A real-time programming environment is also presented.

Performance evaluation of an interactive teleradiology system for real-time teleconsultation in different network environments

International Nuclear Information System (INIS)

Lian Ping; Gong Jun; Zhuang Jun; Sun Jianyong; Yang Yuanyuan; Zhang Jianguo; Meng Lili

2004-01-01

Objective: Measure the performance of self-developed Interoperable teleradiology system at various communication conditions. Methods: Through three different network media ( satellite network, Asymmetrical Digital Subscriber Loop (ADSL), and Shanghai health system's private broadband WAN), Digital images in radiology were transmitted and experiments on teleradiology consultation were applied. Results such as transmission time were recorded, effects of real-time consultation were evaluated subjectively, and experimental data were analyzed. Results: In satellite network, time spent on the transmission of images is long and effects of consultation is normal; in broadband network, time spent is short and no delay is observed in interoperation. Conclusion: teleconsultation can be hold on image sets composed of small matrix size images and compressed large matrix size images in satellite narrowband network, optimum transmission bandwidth is 192 kbps; original large matrix size images such as CR can be transmitted through broadband network and be used in teleconsultation. Real-time interoperation of the system doesn't require very high bandwidth. It can be implemented at various communication conditions

Time in Science: Reversibility vs. Irreversibility

Science.gov (United States)

Pomeau, Yves

To discuss properly the question of irreversibility one needs to make a careful distinction between reversibility of the equations of motion and the choice of the initial conditions. This is also relevant for the rather confuse philosophy of the wave packet reduction in quantum mechanics. The explanation of this reduction requires also to make precise assumptions on what initial data are accessible in our world. Finally I discuss how a given (and long) time record can be shown in an objective way to record an irreversible or reversible process. Or: can a direction of time be derived from its analysis? This leads quite naturally to examine if there is a possible spontaneous breaking of the time reversal symmetry in many body systems, a symmetry breaking that would be put in evidence objectively by looking at certain specific time correlations.

Manipulating motor performance and memory through real-time fMRI neurofeedback

Science.gov (United States)

Scharnowski, Frank; Veit, Ralf; Zopf, Regine; Studer, Petra; Bock, Simon; Diedrichsen, Jörn; Goebel, Rainer; Mathiak, Klaus; Birbaumer, Niels; Weiskopf, Nikolaus

2015-01-01

Task performance depends on ongoing brain activity which can be influenced by attention, arousal, or motivation. However, such modulating factors of cognitive efficiency are unspecific, can be difficult to control, and are not suitable to facilitate neural processing in a regionally specific manner. Here, we non-pharmacologically manipulated regionally specific brain activity using technically sophisticated real-time fMRI neurofeedback. This was accomplished by training participants to simultaneously control ongoing brain activity in circumscribed motor and memory-related brain areas, namely the supplementary motor area and the parahippocampal cortex. We found that learned voluntary control over these functionally distinct brain areas caused functionally specific behavioral effects, i.e. shortening of motor reaction times and specific interference with memory encoding. The neurofeedback approach goes beyond improving cognitive efficiency by unspecific psychological factors such as attention, arousal, or motivation. It allows for directly manipulating sustained activity of task-relevant brain regions in order to yield specific behavioral or cognitive effects. PMID:25796342

Overview of real-time kernels at the Superconducting Super Collider Laboratory

International Nuclear Information System (INIS)

Low, K.; Acharya, S.; Allen, M.; Faught, E.; Haenni, D.; Kalbfleisch, C.

1991-01-01

The Superconducting Super Collider Laboratory (SSCL) will have many subsystems that will require real-time microprocessor control. Examples of such Sub-systems requiring real-time controls are power supply ramp generators and quench protection monitors for the superconducting magnets. The authors plan on using a commercial multitasking real-time kernel in these systems. These kernels must perform in a consistent, reliable and efficient manner. Actual performance measurements have been conducted on four different kernels, all running on the same hardware platform. The measurements fall into two categories. Throughput measurements covering the 'non-real-time' aspects of the kernel include process creation/termination times, interprocess communication facilities involving messages, semaphores and shared memory and memory allocation/deallocation. Measurements concentrating on real-time response are context switch times, interrupt latencies and interrupt task response

Overview of real-time kernels at the Superconducting Super Collider Laboratory

International Nuclear Information System (INIS)

Low, K.; Acharya, S.; Allen, M.; Faught, E.; Haenni, D.; Kalbfleisch, C.

1991-05-01

The Superconducting Super Collider Laboratory (SSCL) will have many subsystems that will require real-time microprocessor control. Examples of such sub-systems requiring real-time controls are power supply ramp generators and quench protection monitors for the superconducting magnets. We plan on using a commercial multitasking real-time kernel in these systems. These kernels must perform in a consistent, reliable and efficient manner. Actual performance measurements have been conducted on four different kernels, all running on the same hardware platform. The measurements fall into two categories. Throughput measurements covering the ''non-real-time'' aspects of the kernel include process creation/termination times, interprocess communication facilities involving messages, semaphores and shared memory and memory allocation/deallocation. Measurements concentrating on real-time response are context switch times, interrupt latencies and interrupt task response. 6 refs., 2 tabs

Real-time performance evaluation of media pipeline plug-in architectures

CSIR Research Space (South Africa)

Sentongo, VN

2011-09-01

Full Text Available Deployment of real-time applications has become ubiquitous in recent years. These applications (e.g. streaming video over the Internet) however, are processor intensive and require fast video-processing techniques for more flexible, efficient...

Real-Time Video Stylization Using Object Flows.

Science.gov (United States)

Lu, Cewu; Xiao, Yao; Tang, Chi-Keung

2017-05-05

We present a real-time video stylization system and demonstrate a variety of painterly styles rendered on real video inputs. The key technical contribution lies on the object flow, which is robust to inaccurate optical flow, unknown object transformation and partial occlusion as well. Since object flows relate regions of the same object across frames, shower-door effect can be effectively reduced where painterly strokes and textures are rendered on video objects. The construction of object flows is performed in real time and automatically after applying metric learning. To reduce temporal flickering, we extend the bilateral filtering into motion bilateral filtering. We propose quantitative metrics to measure the temporal coherence on structures and textures of our stylized videos, and perform extensive experiments to compare our stylized results with baseline systems and prior works specializing in watercolor and abstraction.

Normalization with Corresponding Naïve Tissue Minimizes Bias Caused by Commercial Reverse Transcription Kits on Quantitative Real-Time PCR Results.

Directory of Open Access Journals (Sweden)

Andreas Garcia-Bardon

Full Text Available Real-time reverse transcription polymerase chain reaction (PCR is the gold standard for expression analysis. Designed to improve reproducibility and sensitivity, commercial kits are commonly used for the critical step of cDNA synthesis. The present study was designed to determine the impact of these kits. mRNA from mouse brains were pooled to create serial dilutions ranging from 0.0625 μg to 2 μg, which were transcribed into cDNA using four different commercial reverse-transcription kits. Next, we transcribed mRNA from brain tissue after acute brain injury and naïve mice into cDNA for qPCR. Depending on tested genes, some kits failed to show linear results in dilution series and revealed strong variations in cDNA yield. Absolute expression data in naïve and trauma settings varied substantially between these kits. Normalization with a housekeeping gene failed to reduce kit-dependent variations, whereas normalization eliminated differences when naïve samples from the same region were used. The study shows strong evidence that choice of commercial cDNA synthesis kit has a major impact on PCR results and, consequently, on comparability between studies. Additionally, it provides a solution to overcome this limitation by normalization with data from naïve samples. This simple step helps to compare mRNA expression data between different studies and groups.

Procrastination, Flow, and Academic Performance in Real Time Using the Experience Sampling Method.

Science.gov (United States)

Sumaya, Isabel C; Darling, Emily

2018-01-01

The authors' aim was to first provide an alternative methodology in the assessment of procrastination and flow that would not reply on retrospective or prospective self-reports. Using real-time assessment of both procrastination and flow, the authors investigated how these factors impact academic performance by using the Experience Sampling Method. They assessed flow by measuring student self-reported skill versus challenge, and procrastination by measuring the days to completion of an assignment. Procrastination and flow were measured for six days before a writing assignment due date while students (n = 14) were enrolled in a research methods course. Regardless of status of flow, both the nonflow and flow groups showed high levels of procrastination. Students who experienced flow as they worked on their paper, in real time, earned significantly higher grades (M = 3.05 ± 0.30: an average grade of B) as compared with the nonflow group (M = 1.16 ± 0.33: an average grade of D; p = .007). Additionally, students experiencing flow were more accurate in predicting their grade (difference scores, flow M = 0.12 ± 0.33 vs. nonflow M = 1.39 ± 0.29; p = .015). Students in the nonflow group were nearly a grade and a half off in their prediction of their grade on the paper. To the authors' knowledge, the study is the first to provide experimental evidence showing differences in academic performance between students experiencing flow and nonflow students.

Optical Time Reversal from Time-Dependent Epsilon-Near-Zero Media

Science.gov (United States)

Vezzoli, Stefano; Bruno, Vincenzo; DeVault, Clayton; Roger, Thomas; Shalaev, Vladimir M.; Boltasseva, Alexandra; Ferrera, Marcello; Clerici, Matteo; Dubietis, Audrius; Faccio, Daniele

2018-01-01

Materials with a spatially uniform but temporally varying optical response have applications ranging from magnetic field-free optical isolators to fundamental studies of quantum field theories. However, these effects typically become relevant only for time variations oscillating at optical frequencies, thus presenting a significant hurdle that severely limits the realization of such conditions. Here we present a thin-film material with a permittivity that pulsates (uniformly in space) at optical frequencies and realizes a time-reversing medium of the form originally proposed by Pendry [Science 322, 71 (2008), 10.1126/science.1162087]. We use an optically pumped, 500 nm thick film of epsilon-near-zero (ENZ) material based on Al-doped zinc oxide. An incident probe beam is both negatively refracted and time reversed through a reflected phase-conjugated beam. As a result of the high nonlinearity and the refractive index that is close to zero, the ENZ film leads to time reversed beams (simultaneous negative refraction and phase conjugation) with near-unit efficiency and greater-than-unit internal conversion efficiency. The ENZ platform therefore presents the time-reversal features required, e.g., for efficient subwavelength imaging, all-optical isolators and fundamental quantum field theory studies.

A Distributed Computing Network for Real-Time Systems.

Science.gov (United States)

1980-11-03

7 ) AU2 o NAVA TUNDEWATER SY$TEMS CENTER NEWPORT RI F/G 9/2 UIS RIBUT E 0 COMPUTIN G N LTWORK FOR REAL - TIME SYSTEMS .(U) UASSIFIED NOV Al 6 1...MORAIS - UT 92 dLEVEL c A Distributed Computing Network for Real - Time Systems . 11 𔃺-1 Gordon E/Morson I7 y tm- ,r - t "en t As J 2 -p .. - 7 I’ cNaval...NUMBER TD 5932 / N 4. TITLE mand SubotI. S. TYPE OF REPORT & PERIOD COVERED A DISTRIBUTED COMPUTING NETWORK FOR REAL - TIME SYSTEMS 6. PERFORMING ORG

Expert systems for real-time monitoring and fault diagnosis

Science.gov (United States)

Edwards, S. J.; Caglayan, A. K.

1989-01-01

Methods for building real-time onboard expert systems were investigated, and the use of expert systems technology was demonstrated in improving the performance of current real-time onboard monitoring and fault diagnosis applications. The potential applications of the proposed research include an expert system environment allowing the integration of expert systems into conventional time-critical application solutions, a grammar for describing the discrete event behavior of monitoring and fault diagnosis systems, and their applications to new real-time hardware fault diagnosis and monitoring systems for aircraft.

Performance optimization of PM-16QAM transmission system enabled by real-time self-adaptive coding.

Science.gov (United States)

Qu, Zhen; Li, Yao; Mo, Weiyang; Yang, Mingwei; Zhu, Shengxiang; Kilper, Daniel C; Djordjevic, Ivan B

2017-10-15

We experimentally demonstrate self-adaptive coded 5×100  Gb/s WDM polarization multiplexed 16 quadrature amplitude modulation transmission over a 100 km fiber link, which is enabled by a real-time control plane. The real-time optical signal-to-noise ratio (OSNR) is measured using an optical performance monitoring device. The OSNR measurement is processed and fed back using control plane logic and messaging to the transmitter side for code adaptation, where the binary data are adaptively encoded with three types of low-density parity-check (LDPC) codes with code rates of 0.8, 0.75, and 0.7 of large girth. The total code-adaptation latency is measured to be 2273 ms. Compared with transmission without adaptation, average net capacity improvements of 102%, 36%, and 7.5% are obtained, respectively, by adaptive LDPC coding.

Elastic least-squares reverse time migration

KAUST Repository

Feng, Zongcai; Schuster, Gerard T.

2016-01-01

Elastic least-squares reverse time migration (LSRTM) is used to invert synthetic particle-velocity data and crosswell pressure field data. The migration images consist of both the P- and Svelocity perturbation images. Numerical tests on synthetic and field data illustrate the advantages of elastic LSRTM over elastic reverse time migration (RTM). In addition, elastic LSRTM images are better focused and have better reflector continuity than do the acoustic LSRTM images.

Elastic least-squares reverse time migration

KAUST Repository

Feng, Zongcai

2016-09-06

Elastic least-squares reverse time migration (LSRTM) is used to invert synthetic particle-velocity data and crosswell pressure field data. The migration images consist of both the P- and Svelocity perturbation images. Numerical tests on synthetic and field data illustrate the advantages of elastic LSRTM over elastic reverse time migration (RTM). In addition, elastic LSRTM images are better focused and have better reflector continuity than do the acoustic LSRTM images.

Real-Time Operating Systems for Multicore Embedded Systems

OpenAIRE

Tomiyama, Hiroyuki; Honda, Shinya; Takada, Hiroaki

2008-01-01

Multicore systems-on-chip have become popular inthe design of embedded systems in order to simultaneously achieve high performance and low power consumption. On the software side, real-time operating systems are necessary in orderto handle growing complexity of embedded software. This paper describes requirements, design principles and implementation techniques for real-time operating systems to be used inasymmetric multicore systems.

Design and performance of the CDC real-time reverse transcriptase PCR swine flu panel for detection of 2009 A (H1N1) pandemic influenza virus.

Science.gov (United States)

Shu, Bo; Wu, Kai-Hui; Emery, Shannon; Villanueva, Julie; Johnson, Roy; Guthrie, Erica; Berman, LaShondra; Warnes, Christine; Barnes, Nathelia; Klimov, Alexander; Lindstrom, Stephen

2011-07-01

Swine influenza viruses (SIV) have been shown to sporadically infect humans and are infrequently identified by the Influenza Division of the Centers for Disease Control and Prevention (CDC) after being received as unsubtypeable influenza A virus samples. Real-time reverse transcriptase PCR (rRT-PCR) procedures for detection and characterization of North American lineage (N. Am) SIV were developed and implemented at CDC for rapid identification of specimens from cases of suspected infections with SIV. These procedures were utilized in April 2009 for detection of human cases of 2009 A (H1N1) pandemic (pdm) influenza virus infection. Based on genetic sequence data derived from the first two viruses investigated, the previously developed rRT-PCR procedures were optimized to create the CDC rRT-PCR Swine Flu Panel for detection of the 2009 A (H1N1) pdm influenza virus. The analytical sensitivity of the CDC rRT-PCR Swine Flu Panel was shown to be 5 copies of RNA per reaction and 10(-1.3 - -0.7) 50% infectious doses (ID(50)) per reaction for cultured viruses. Cross-reactivity was not observed when testing human clinical specimens or cultured viruses that were positive for human seasonal A (H1N1, H3N2) and B influenza viruses. The CDC rRT-PCR Swine Flu Panel was distributed to public health laboratories in the United States and internationally from April 2009 until June 2010. The CDC rRT-PCR Swine Flu Panel served as an effective tool for timely and specific detection of 2009 A (H1N1) pdm influenza viruses and facilitated subsequent public health response implementation.

Real-Time Performance of a Self-Powered Environmental IoT Sensor Network System.

Science.gov (United States)

Wu, Fan; Rüdiger, Christoph; Yuce, Mehmet Rasit

2017-02-01

Wireless sensor networks (WSNs) play an increasingly important role in monitoring applications in many areas. With the emergence of the Internet-of-Things (IoT), many more lowpower sensors will need to be deployed in various environments to collect and monitor data about environmental factors in real time. Providing power supply to these sensor nodes becomes a critical challenge for realizations of IoT applications as sensor nodes are normally battery-powered and have a limited lifetime. This paper proposes a wireless sensor network that is powered by solar energy harvesting. The sensor network monitors the environmental data with low-power sensor electronics and forms a network using multiple XBee wireless modules. A detailed performance analysis of the network system under solar energy harvesting has been presented. The sensor network system and the proposed energy-harvesting techniques are configured to achieve a continuous energy source for the sensor network. The proposed energy-harvesting system has been successfully designed to enable an energy solution in order to keep sensor nodes active and reliable for a whole day. The paper also outlines some of our experiences in real-time implementation of a sensor network system with energy harvesting.

Real-Time Performance of a Self-Powered Environmental IoT Sensor Network System

Directory of Open Access Journals (Sweden)

Fan Wu

2017-02-01

Full Text Available Wireless sensor networks (WSNs play an increasingly important role in monitoring applications in many areas. With the emergence of the Internet-of-Things (IoT, many more lowpower sensors will need to be deployed in various environments to collect and monitor data about environmental factors in real time. Providing power supply to these sensor nodes becomes a critical challenge for realizations of IoT applications as sensor nodes are normally battery-powered and have a limited lifetime. This paper proposes a wireless sensor network that is powered by solar energy harvesting. The sensor network monitors the environmental data with low-power sensor electronics and forms a network using multiple XBee wireless modules. A detailed performance analysis of the network system under solar energy harvesting has been presented. The sensor network system and the proposed energy-harvesting techniques are configured to achieve a continuous energy source for the sensor network. The proposed energy-harvesting system has been successfully designed to enable an energy solution in order to keep sensor nodes active and reliable for a whole day. The paper also outlines some of our experiences in real-time implementation of a sensor network system with energy harvesting.

Process algebra with timing : real time and discrete time

NARCIS (Netherlands)

Baeten, J.C.M.; Middelburg, C.A.; Bergstra, J.A.; Ponse, A.J.; Smolka, S.A.

2001-01-01

We present real time and discrete time versions of ACP with absolute timing and relative timing. The starting-point is a new real time version with absolute timing, called ACPsat, featuring urgent actions and a delay operator. The discrete time versions are conservative extensions of the discrete

Process algebra with timing: Real time and discrete time

NARCIS (Netherlands)

Baeten, J.C.M.; Middelburg, C.A.

1999-01-01

We present real time and discrete time versions of ACP with absolute timing and relative timing. The startingpoint is a new real time version with absolute timing, called ACPsat , featuring urgent actions and a delay operator. The discrete time versions are conservative extensions of the discrete

Evaluation of Real-Time and Off-Line Performance of the Virtual Seismologist Earthquake Early Warning Algorithm in Switzerland

Science.gov (United States)

Behr, Yannik; Clinton, John; Cua, Georgia; Cauzzi, Carlo; Heimers, Stefan; Kästli, Philipp; Becker, Jan; Heaton, Thomas

2013-04-01

The Virtual Seismologist (VS) method is a Bayesian approach to regional network-based earthquake early warning (EEW) originally formulated by Cua and Heaton (2007). Implementation of VS into real-time EEW codes has been an on-going effort of the Swiss Seismological Service at ETH Zürich since 2006, with support from ETH Zürich, various European projects, and the United States Geological Survey (USGS). VS is one of three EEW algorithms that form the basis of the California Integrated Seismic Network (CISN) ShakeAlert system, a USGS-funded prototype end-to-end EEW system that could potentially be implemented in California. In Europe, VS is currently operating as a real-time test system in Switzerland. As part of the on-going EU project REAKT (Strategies and Tools for Real-Time Earthquake Risk Reduction), VS installations in southern Italy, western Greece, Istanbul, Romania, and Iceland are planned or underway. In Switzerland, VS has been running in real-time on stations monitored by the Swiss Seismological Service (including stations from Austria, France, Germany, and Italy) since 2010. While originally based on the Earthworm system it has recently been ported to the SeisComp3 system. Besides taking advantage of SeisComp3's picking and phase association capabilities it greatly simplifies the potential installation of VS at networks in particular those already running SeisComp3. We present the architecture of the new SeisComp3 based version and compare its results from off-line tests with the real-time performance of VS in Switzerland over the past two years. We further show that the empirical relationships used by VS to estimate magnitudes and ground motion, originally derived from southern California data, perform well in Switzerland.

Real-time reactor coolant system pressure/temperature limit system

International Nuclear Information System (INIS)

Newton, D.G.; Schemmel, R.R.; Van Scooter, W.E. Jr.

1991-01-01

This patent describes an system, used in controlling the operating of a nuclear reactor coolant system, which automatically calculates and displays allowable reactor coolant system pressure/temperature limits within the nuclear reactor coolant system based upon real-time inputs. It comprises: means for producing signals representative of real-time operating parameters of the nuclear reactor cooling system; means for developing pressure and temperature limits relating the real-time operating parameters of the nuclear reactor coolant system, for normal and emergency operation thereof; means for processing the signals representative of real-time operating parameters of the nuclear reactor coolant system to perform calculations of a best estimate of signals, check manual inputs against permissible valves and test data acquisition hardware for validity and over/under range; and means for comparing the representative signals with limits for the real-time operating parameters to produce a signal for a real-time display of the pressure and temperature limits and of the real-time operating parameters use an operator in controlling the operation of the nuclear reactor coolant system

Real-time PCR assays for hepatitis B virus DNA quantification may require two different targets.

Science.gov (United States)

Liu, Chao; Chang, Le; Jia, Tingting; Guo, Fei; Zhang, Lu; Ji, Huimin; Zhao, Junpeng; Wang, Lunan

2017-05-12

Quantification Hepatitis B virus (HBV) DNA plays a critical role in the management of chronic HBV infections. However, HBV is a DNA virus with high levels of genetic variation, and drug-resistant mutations have emerged with the use of antiviral drugs. If a mutation caused a sequence mismatched in the primer or probe of a commercial DNA quantification kit, this would lead to an underestimation of the viral load of the sample. The aim of this study was to determine whether commercial kits, which use only one pair of primers and a single probe, accurately quantify the HBV DNA levels and to develop an improved duplex real-time PCR assay. We developed a new duplex real-time PCR assay that used two pairs of primers and two probes based on the conserved S and C regions of the HBV genome. We performed HBV DNA quantitative detection of HBV samples and compared the results of our duplex real-time PCR assays with the COBAS TaqMan HBV Test version 2 and Daan real-time PCR assays. The target region of the discordant sample was amplified, sequenced, and validated using plasmid. The results of the duplex real-time PCR were in good accordance with the commercial COBAS TaqMan HBV Test version 2 and Daan real-time PCR assays. We showed that two samples from Chinese HBV infections underestimated viral loads when quantified by the Roche kit because of a mismatch between the viral sequence and the reverse primer of the Roche kit. The HBV DNA levels of six samples were undervalued by duplex real-time PCR assays of the C region because of mutations in the primer of C region. We developed a new duplex real-time PCR assay, and the results of this assay were similar to the results of commercial kits. The HBV DNA level could be undervalued when using the COBAS TaqMan HBV Test version 2 for Chinese HBV infections owing to a mismatch with the primer/probe. A duplex real-time PCR assay based on the S and C regions could solve this problem to some extent.

Validation of Magnetic Reconstruction Codes for Real-Time Applications

International Nuclear Information System (INIS)

Mazon, D.; Murari, A.; Boulbe, C.; Faugeras, B.; Blum, J.; Svensson, J.; Quilichini, T.; Gelfusa, M.

2010-01-01

The real-time reconstruction of the plasma magnetic equilibrium in a tokamak is a key point to access high-performance regimes. Indeed, the shape of the plasma current density profile is a direct output of the reconstruction and has a leading effect for reaching a steady-state high-performance regime of operation. The challenge is thus to develop real-time methods and algorithms that reconstruct the magnetic equilibrium from the perspective of using these outputs for feedback control purposes. In this paper the validation of the JET real-time equilibrium reconstruction codes using both a Bayesian approach and a full equilibrium solver named Equinox will be detailed, the comparison being performed with the off-line equilibrium code EFIT (equilibrium fitting) or the real-time boundary reconstruction code XLOC (X-point local expansion). In this way a significant database, a methodology, and a strategy for the validation are presented. The validation of the results has been performed using a validated database of 130 JET discharges with a large variety of magnetic configurations. Internal measurements like polarimetry and motional Stark effect have been also used for the Equinox validation including some magnetohydrodynamic signatures for the assessment of the reconstructed safety profile and current density. (authors)

Performance analysis of a real-time database with optimistic concurrency control

NARCIS (Netherlands)

Sassen, S.A.E.; Wal, van der J.

1997-01-01

For a real-time shared-memory database with Optimistic Concurrency Control (OCC), an approximation for the transaction response-time distribution and thus for the deadline miss probability is obtained. Transactions arrive at the database according to a Poisson process. There is a limited number of

Real-Time Imaging System for the OpenPET

Science.gov (United States)

Tashima, Hideaki; Yoshida, Eiji; Kinouchi, Shoko; Nishikido, Fumihiko; Inadama, Naoko; Murayama, Hideo; Suga, Mikio; Haneishi, Hideaki; Yamaya, Taiga

2012-02-01

The OpenPET and its real-time imaging capability have great potential for real-time tumor tracking in medical procedures such as biopsy and radiation therapy. For the real-time imaging system, we intend to use the one-pass list-mode dynamic row-action maximum likelihood algorithm (DRAMA) and implement it using general-purpose computing on graphics processing units (GPGPU) techniques. However, it is difficult to make consistent reconstructions in real-time because the amount of list-mode data acquired in PET scans may be large depending on the level of radioactivity, and the reconstruction speed depends on the amount of the list-mode data. In this study, we developed a system to control the data used in the reconstruction step while retaining quantitative performance. In the proposed system, the data transfer control system limits the event counts to be used in the reconstruction step according to the reconstruction speed, and the reconstructed images are properly intensified by using the ratio of the used counts to the total counts. We implemented the system on a small OpenPET prototype system and evaluated the performance in terms of the real-time tracking ability by displaying reconstructed images in which the intensity was compensated. The intensity of the displayed images correlated properly with the original count rate and a frame rate of 2 frames per second was achieved with average delay time of 2.1 s.

Survey of real-time processing systems for big data

DEFF Research Database (Denmark)

Liu, Xiufeng; Lftikhar, Nadeem; Xie, Xike

2014-01-01

In recent years, real-time processing and analytics systems for big data–in the context of Business Intelligence (BI)–have received a growing attention. The traditional BI platforms that perform regular updates on daily, weekly or monthly basis are no longer adequate to satisfy the fast......-changing business environments. However, due to the nature of big data, it has become a challenge to achieve the real-time capability using the traditional technologies. The recent distributed computing technology, MapReduce, provides off-the-shelf high scalability that can significantly shorten the processing time...... for big data; Its open-source implementation such as Hadoop has become the de-facto standard for processing big data, however, Hadoop has the limitation of supporting real-time updates. The improvements in Hadoop for the real-time capability, and the other alternative real-time frameworks have been...

Comparison of multiplex RT-PCR and real-time HybProbe assay for serotyping of dengue virus using reference strains and clinical samples from India

Directory of Open Access Journals (Sweden)

Anita Chakravarti

2016-01-01

Full Text Available Background: Dengue virus serotyping is crucial from clinical management and epidemiological point of view. Aims: To compare efficacy of two molecular detection and typing methods, namely, multiplex reverse transcription polymerase chain reaction (RT-PCR and real-time Hybprobe assay using a panel of known dilution of four reference Dengue virus strains and a panel of sera collected from clinically suspected dengue patients. Settings: This study was conducted at a tertiary-care teaching hospital in Delhi, India. Materials and Methods: Dengue serotype specific virus strains were used as prototypes for serotyping assays. Viral load was quantified by quantitative real time reverse transcription polymerase chain reaction (qRT-PCR. Acute phase serum samples were collected from 79 patients with clinically suspected Dengue fever on their first day of presentation during September-October 2012. Viral RNA from serum and cell culture supernatant was extracted. Reverse transcription was carried out. Quantitative detection of DENV RNA from reference strain culture supernatants and each of the 79 patient samples by real-time PCR was performed using light cycler Taqman master mix kit. Serotyping was done by multiplex RT-PCR assay and Hybprobe assay. Results: The multiplex RT-PCR assay, though found to be 100% specific, couldn't serotype either patient or reference strains with viral load less than 1000 RNA copies/ml. The Hybprobe assay was found to have 100% specificity and had a lower limit of serotype detection of merely 3.54 RNA copies/ml. Conclusions: HybProbe assay has an important role especially in situations where serotyping is to be performed in clinical samples with low viral load.

Static Profiling of the Worst-Case in Real-Time Programs

DEFF Research Database (Denmark)

Brandner, Florian; Hepp, Stefan; Jordan, Alexander

2012-01-01

With the increasing performance demand in real-time systems it becomes more and more relevant to provide feedback to engineers and programmers, but also software development tools, on the performance-relevant code parts of a real-time program. So far, the information provided to programmers through...... other code parts. To give an accurate view covering the entire code base, tools in the spirit of standard program profiling tools are required. This work proposes an efficient approach to compute worst-case timing information for all code parts of a program using a complementary metric, called...... criticality. Every statement of a real-time program is assigned a criticality value, expressing how critical the respective code is with respect to the global WCET. This gives an accurate view to programmers how close the worst execution path passing through a specific part of a real-time program...

System Integration for Real-Time Mobile Manipulation

Directory of Open Access Journals (Sweden)

Reza Oftadeh

2014-03-01

Full Text Available Mobile manipulators are one of the most complicated types of mechatronics systems. The performance of these robots in performing complex manipulation tasks is highly correlated with the synchronization and integration of their low-level components. This paper discusses in detail the mechatronics design of a four wheel steered mobile manipulator. It presents the manipulator's mechanical structure and electrical interfaces, designs low-level software architecture based on embedded PC-based controls, and proposes a systematic solution based on code generation products of MATLAB and Simulink. The remote development environment described here is used to develop real-time controller software and modules for the mobile manipulator under a POSIX-compliant, real-time Linux operating system. Our approach enables developers to reliably design controller modules that meet the hard real-time constraints of the entire low-level system architecture. Moreover, it provides a systematic framework for the development and integration of hardware devices with various communication mediums and protocols, which facilitates the development and integration process of the software controller.

Performance of the Abbott RealTime CT/NG for Detection of Chlamydia trachomatis and Neisseria gonorrhoeae▿

Science.gov (United States)

Gaydos, C. A.; Cartwright, C. P.; Colaninno, P.; Welsch, J.; Holden, J.; Ho, S. Y.; Webb, E. M.; Anderson, C.; Bertuzis, R.; Zhang, L.; Miller, T.; Leckie, G.; Abravaya, K.; Robinson, J.

2010-01-01

A multicenter clinical study was conducted to evaluate the performance characteristics of the Abbott RealTime CT/NG assay, a multiplex real-time PCR assay, for simultaneous detection of Chlamydia trachomatis and Neisseria gonorrhoeae. The specimens were collected from a total of 3,832 male and female subjects at 16 geographically diverse sites. Specimens included male and female urine samples, male urethral swabs, female endocervical swabs, and self-collected and clinician-collected vaginal swabs. Specimens were tested with the automated Abbott RealTime CT/NG assay, Aptima Combo 2 assay (Gen-Probe), ProbeTec ET CT/GC assay (Becton Dickinson), and culture for N. gonorrhoeae. The Aptima Combo 2 assay, the ProbeTec assay, and the N. gonorrhoeae culture were used as the reference assays. For each subject, a patient infected status (PIS) was determined based on the combined results from the reference assays. The overall prevalence in female subjects was 8.9% for C. trachomatis and 3.8% for N. gonorrhoeae. The overall male prevalence was 18.2% for C. trachomatis and 16.7% for N. gonorrhoeae. The overall sensitivity and specificity of the Abbott RealTime CT/NG assay were 92.4% and 99.2% for C. trachomatis and 96.9% and 99.7% for N. gonorrhoeae, respectively. In comparison, the sensitivity and specificity, respectively, for the Aptima Combo 2 assay were 94.5% and 99.0% for C. trachomatis and 96.1% and 99.5% for N. gonorrhoeae, and those for the ProbeTec ET assay were 90.3% and 99.5% for C. trachomatis and 92.0% and 97.3% for N. gonorrhoeae in this study. The Abbott RealTime CT/NG assay offers C. trachomatis and N. gonorrhoeae dual detection with high sensitivity and specificity. The automated assay provides a useful alternative nucleic acid amplification assay for clinical laboratories and clinicians. PMID:20668135

Performance of the Abbott RealTime CT/NG for detection of Chlamydia trachomatis and Neisseria gonorrhoeae.

Science.gov (United States)

Gaydos, C A; Cartwright, C P; Colaninno, P; Welsch, J; Holden, J; Ho, S Y; Webb, E M; Anderson, C; Bertuzis, R; Zhang, L; Miller, T; Leckie, G; Abravaya, K; Robinson, J

2010-09-01

A multicenter clinical study was conducted to evaluate the performance characteristics of the Abbott RealTime CT/NG assay, a multiplex real-time PCR assay, for simultaneous detection of Chlamydia trachomatis and Neisseria gonorrhoeae. The specimens were collected from a total of 3,832 male and female subjects at 16 geographically diverse sites. Specimens included male and female urine samples, male urethral swabs, female endocervical swabs, and self-collected and clinician-collected vaginal swabs. Specimens were tested with the automated Abbott RealTime CT/NG assay, Aptima Combo 2 assay (Gen-Probe), ProbeTec ET CT/GC assay (Becton Dickinson), and culture for N. gonorrhoeae. The Aptima Combo 2 assay, the ProbeTec assay, and the N. gonorrhoeae culture were used as the reference assays. For each subject, a patient infected status (PIS) was determined based on the combined results from the reference assays. The overall prevalence in female subjects was 8.9% for C. trachomatis and 3.8% for N. gonorrhoeae. The overall male prevalence was 18.2% for C. trachomatis and 16.7% for N. gonorrhoeae. The overall sensitivity and specificity of the Abbott RealTime CT/NG assay were 92.4% and 99.2% for C. trachomatis and 96.9% and 99.7% for N. gonorrhoeae, respectively. In comparison, the sensitivity and specificity, respectively, for the Aptima Combo 2 assay were 94.5% and 99.0% for C. trachomatis and 96.1% and 99.5% for N. gonorrhoeae, and those for the ProbeTec ET assay were 90.3% and 99.5% for C. trachomatis and 92.0% and 97.3% for N. gonorrhoeae in this study. The Abbott RealTime CT/NG assay offers C. trachomatis and N. gonorrhoeae dual detection with high sensitivity and specificity. The automated assay provides a useful alternative nucleic acid amplification assay for clinical laboratories and clinicians.

Focusing over Optical Fiber Using Time Reversal

DEFF Research Database (Denmark)

Piels, Molly; Porto da Silva, Edson; Estaran Tolosa, Jose Manuel

2015-01-01

A time-reversal array in multimode fiber is proposed for lossless remotely controlled switching using passive optical splitters. The signal to be transmitted is digitally pre-distorted so that it is routed through the physical layer in order to arrive at only one receiver in an array. System...... performance in the presence of additive white gaussian noise, modal group delay, and timing error is investigated numerically for single-mode and 10-mode fiber. Focusing using a two-transmitter array and 44 km of single- mode fiber is demonstrated experimentally for 3 GBd QPSK signals with a bit error rate...

Time synchronization for an Ethernet-based real-time token network

NARCIS (Netherlands)

Hanssen, F.T.Y.; van den Boom, Joost; Jansen, P.G.; Scholten, Johan

We present a distributed clock synchronization algorithm. It performs clock synchronization on an Ethernet-based real-time token local area network, without the use of an external clock source. It is used to enable the token schedulers in each node to agree upon a common time. Its intended use is in

Real-time radiography

International Nuclear Information System (INIS)

Bossi, R.H.; Oien, C.T.

1981-01-01

Real-time radiography is used for imaging both dynamic events and static objects. Fluorescent screens play an important role in converting radiation to light, which is then observed directly or intensified and detected. The radiographic parameters for real-time radiography are similar to conventional film radiography with special emphasis on statistics and magnification. Direct-viewing fluoroscopy uses the human eye as a detector of fluorescent screen light or the light from an intensifier. Remote-viewing systems replace the human observer with a television camera. The remote-viewing systems have many advantages over the direct-viewing conditions such as safety, image enhancement, and the capability to produce permanent records. This report reviews real-time imaging system parameters and components

Movement retraining using real-time feedback of performance.

Science.gov (United States)

Hunt, Michael Anthony

2013-01-17

Any modification of movement - especially movement patterns that have been honed over a number of years - requires re-organization of the neuromuscular patterns responsible for governing the movement performance. This motor learning can be enhanced through a number of methods that are utilized in research and clinical settings alike. In general, verbal feedback of performance in real-time or knowledge of results following movement is commonly used clinically as a preliminary means of instilling motor learning. Depending on patient preference and learning style, visual feedback (e.g. through use of a mirror or different types of video) or proprioceptive guidance utilizing therapist touch, are used to supplement verbal instructions from the therapist. Indeed, a combination of these forms of feedback is commonplace in the clinical setting to facilitate motor learning and optimize outcomes. Laboratory-based, quantitative motion analysis has been a mainstay in research settings to provide accurate and objective analysis of a variety of movements in healthy and injured populations. While the actual mechanisms of capturing the movements may differ, all current motion analysis systems rely on the ability to track the movement of body segments and joints and to use established equations of motion to quantify key movement patterns. Due to limitations in acquisition and processing speed, analysis and description of the movements has traditionally occurred offline after completion of a given testing session. This paper will highlight a new supplement to standard motion analysis techniques that relies on the near instantaneous assessment and quantification of movement patterns and the display of specific movement characteristics to the patient during a movement analysis session. As a result, this novel technique can provide a new method of feedback delivery that has advantages over currently used feedback methods.

Real-Time Communications in Autonomic Networks: System Implementation and Performance Evaluation

Directory of Open Access Journals (Sweden)

C. Tselios

2012-01-01

Full Text Available This paper describes the design and prototype implementation of a communication platform aiming to provide voice and video communication in a distributed networking environment. Performance considerations and network characteristics have also been taken into account in order to provide the set of properties dictated by the sensitive nature and the real-time characteristics of the targeted application scenarios. The proposed system has been evaluated both by experimental means as well as subjective tests taken by an extensive number of users. The results show that the proposed platform operates seamlessly in two hops, while in the four hops scenario, audio and video are delivered with marginal distortion. The conducted survey indicates that the user experience in terms of Quality of Service has obtained higher scores in the scenario with the two hops.

Abrupt category shifts during real-time person perception.

Science.gov (United States)

Freeman, Jonathan B

2014-02-01

Previous studies have suggested that real-time person perception relies on continuous competition, in which partially active categories smoothly compete over time. Here, two studies demonstrated the involvement of a different kind of competition. In Study 1, before participants selected the correct sex category for morphed faces, their mouse trajectories often exhibited a continuous attraction toward the incorrect category that increased with sex-category ambiguity, indicating continuous competition. On other trials, however, trajectories initially pursued the incorrect category and then abruptly redirected toward the correct category, suggesting early incorrect category activation that was rapidly reversed later in processing. These abrupt category reversals also increased with ambiguity. In Study 2, participants were presented with faces containing a sex-typical or sex-atypical hair cue, in a context in which the norm was either sex-typical targets (normative context) or sex-atypical targets (counternormative context). Sex-atypical targets induced greater competition in the normative context, but sex-typical targets induced greater competition in the counternormative context. Together, these results demonstrate that categorizing others involves both smooth competition and abrupt category shifts, and that these flexibly adapt to the social context.

Real-time vision systems

Energy Technology Data Exchange (ETDEWEB)

Johnson, R.; Hernandez, J.E.; Lu, Shin-yee [Lawrence Livermore National Lab., CA (United States)

1994-11-15

Many industrial and defence applications require an ability to make instantaneous decisions based on sensor input of a time varying process. Such systems are referred to as `real-time systems` because they process and act on data as it occurs in time. When a vision sensor is used in a real-time system, the processing demands can be quite substantial, with typical data rates of 10-20 million samples per second. A real-time Machine Vision Laboratory (MVL) was established in FY94 to extend our years of experience in developing computer vision algorithms to include the development and implementation of real-time vision systems. The laboratory is equipped with a variety of hardware components, including Datacube image acquisition and processing boards, a Sun workstation, and several different types of CCD cameras, including monochrome and color area cameras and analog and digital line-scan cameras. The equipment is reconfigurable for prototyping different applications. This facility has been used to support several programs at LLNL, including O Division`s Peacemaker and Deadeye Projects as well as the CRADA with the U.S. Textile Industry, CAFE (Computer Aided Fabric Inspection). To date, we have successfully demonstrated several real-time applications: bullet tracking, stereo tracking and ranging, and web inspection. This work has been documented in the ongoing development of a real-time software library.

Time reversal communication system

Science.gov (United States)

Candy, James V.; Meyer, Alan W.

2008-12-02

A system of transmitting a signal through a channel medium comprises digitizing the signal, time-reversing the digitized signal, and transmitting the signal through the channel medium. The channel medium may be air, earth, water, tissue, metal, and/or non-metal.

Detection of three porcine vesicular viruses using multiplex real-time primer-probe energy transfer

DEFF Research Database (Denmark)

Rasmussen, Thomas Bruun; Uttenthal, Åse; Aguero, M.

2006-01-01

Rapid identification of the etiologic agent in infected animals is important for the control of an outbreak of vesicular disease in livestock. We have in the present study developed a multiplex real-time reverse transcription-PCR, based on primer-probe energy transfer (PriProET), for simultaneous...

Using Sun’s Java Real-Time System to Manage Behavior-Based Mobile Robot Controllers

Directory of Open Access Journals (Sweden)

Andrew McKenzie

2011-01-01

Full Text Available Implementing a robot controller that can effectively manage limited resources in a deterministic, real-time manner is challenging. Behavior-based architectures that decompose autonomy into levels of intelligence are popular due to their robustness but do not provide real-time features that enforce timing constraints or support determinism. We propose an architecture and approach for using the real-time features of the Real-Time Specification for Java (RTSJ in a behavior-based mobile robot controller to show that timing constraints affect performance. This is accomplished by extending a real-time aware architecture that explicitly enumerates timing requirements for each behavior. It is not enough to reduce latency. The usefulness of this approach is demonstrated via an implementation on Solaris 10 and the Sun Java Real-Time System (Java RTS. Experimental results are obtained using a K-team Koala robot performing path following with four composite behaviors. Experiments were conducted using several task period sets in three cases: real-time threads with the real-time garbage collector, real-time threads with the non- real-time garbage collector, and non-real-time threads with the non-real-time garbage collector. Results show that even if latency and determinism are improved, the timing of each individual behavior significantly affects task performance.

Simultaneous real-time monitoring of multiple cortical systems.

Science.gov (United States)

Gupta, Disha; Jeremy Hill, N; Brunner, Peter; Gunduz, Aysegul; Ritaccio, Anthony L; Schalk, Gerwin

2014-10-01

Real-time monitoring of the brain is potentially valuable for performance monitoring, communication, training or rehabilitation. In natural situations, the brain performs a complex mix of various sensory, motor or cognitive functions. Thus, real-time brain monitoring would be most valuable if (a) it could decode information from multiple brain systems simultaneously, and (b) this decoding of each brain system were robust to variations in the activity of other (unrelated) brain systems. Previous studies showed that it is possible to decode some information from different brain systems in retrospect and/or in isolation. In our study, we set out to determine whether it is possible to simultaneously decode important information about a user from different brain systems in real time, and to evaluate the impact of concurrent activity in different brain systems on decoding performance. We study these questions using electrocorticographic signals recorded in humans. We first document procedures for generating stable decoding models given little training data, and then report their use for offline and for real-time decoding from 12 subjects (six for offline parameter optimization, six for online experimentation). The subjects engage in tasks that involve movement intention, movement execution and auditory functions, separately, and then simultaneously. Main Results: Our real-time results demonstrate that our system can identify intention and movement periods in single trials with an accuracy of 80.4% and 86.8%, respectively (where 50% would be expected by chance). Simultaneously, the decoding of the power envelope of an auditory stimulus resulted in an average correlation coefficient of 0.37 between the actual and decoded power envelopes. These decoders were trained separately and executed simultaneously in real time. This study yielded the first demonstration that it is possible to decode simultaneously the functional activity of multiple independent brain systems. Our

Real-Time Software for the Compass Tokamak Plasma Control

Energy Technology Data Exchange (ETDEWEB)

Valcarcel, D.F.; Duarte, A.S.; Neto, A.; Carvalho, I.S.; Carvalho, B.B.; Fernandes, H.; Sousa, J. [Instituto de Plasmas e Fusao Nuclear, Instituto Superior Tecnico, Lisboa (Portugal); Sartori, F. [Euratom-UKAEA, Culham Science Centre, Abingdon, OX14 3DB Oxon (United Kingdom); Janky, F.; Cahyna, P.; Hron, M.; Panek, R. [Institute of Plasma Physics AS CR, v.v.i., Association EURATOM / IPP.CR, Prague (Costa Rica)

2009-07-01

This poster presents the flexible and high-performance real time system that guarantees the desired time cycles for plasma control on the COMPASS tokamak: 500 {mu}s for toroidal field, current, equilibrium and shaping; 50 {mu}s for fast control of the equilibrium and vertical instability. This system was developed on top of a high-performance processor and a software framework (MARTe) tailored for real-time. The preliminary measurements indicate that the time constraints will be met on the final solution. The system allows the making of modifications in the future to improve software components. (A.C.)

Reduction Methods for Real-time Simulations in Hybrid Testing

DEFF Research Database (Denmark)

Andersen, Sebastian

2016-01-01

Hybrid testing constitutes a cost-effective experimental full scale testing method. The method was introduced in the 1960's by Japanese researchers, as an alternative to conventional full scale testing and small scale material testing, such as shake table tests. The principle of the method...... is performed on a glass fibre reinforced polymer composite box girder. The test serves as a pilot test for prospective real-time tests on a wind turbine blade. The Taylor basis is implemented in the test, used to perform the numerical simulations. Despite of a number of introduced errors in the real...... is to divide a structure into a physical substructure and a numerical substructure, and couple these in a test. If the test is conducted in real-time it is referred to as real time hybrid testing. The hybrid testing concept has developed significantly since its introduction in the 1960', both with respect...

Time reversibility of quantum diffusion in small-world networks

Science.gov (United States)

Han, Sung-Guk; Kim, Beom Jun

2012-02-01

We study the time-reversal dynamics of a tight-binding electron in the Watts-Strogatz (WS) small-world networks. The localized initial wave packet at time t = 0 diffuses as time proceeds until the time-reversal operation, together with the momentum perturbation of the strength η, is made at the reversal time T. The time irreversibility is measured by I = |Π( t = 2 T) - Π( t = 0)|, where Π is the participation ratio gauging the extendedness of the wavefunction and for convenience, t is measured forward even after the time reversal. When η = 0, the time evolution after T makes the wavefunction at t = 2 T identical to the one at t = 0, and we find I = 0, implying a null irreversibility or a complete reversibility. On the other hand, as η is increased from zero, the reversibility becomes weaker, and we observe enhancement of the irreversibility. We find that I linearly increases with increasing η in the weakly-perturbed region, and that the irreversibility is much stronger in the WS network than in the local regular network.

Real time control of plasmas and ECRH systems on TCV

International Nuclear Information System (INIS)

Paley, J.I.; Berrino, J.; Coda, S.; Duval, B.P.; Felici, F.; Goodman, T.P.; Martin, Y.; Moret, J.M.; Piras, F.; Cruz, N.; Rodriques, A.P.; Santos, B.; Varandas, C.A.F.

2009-01-01

Developments in the real time control hardware on Tokamak a Configuration Variable (TCV) coupled with the flexibility of plasma shaping and electron cyclotron (EC) heating and current drive actuators are opening many opportunities to perform real time experiments and develop algorithms and methods for fusion applications. The ability to control magnetohydrodynamic instabilities is particularly important for achieving high performance fusion plasmas and EC is envisaged as a key actuator in maintaining high performance. We have successfully demonstrated control of the sawtooth instability using the EC launcher injection angle to modify the current profile around the q =1 surface. This paper presents an overview of recent real time control experiments on TCV, developments in the hardware and algorithms together with plans for the future.

Manipulating motor performance and memory through real-time fMRI neurofeedback.

Science.gov (United States)

Scharnowski, Frank; Veit, Ralf; Zopf, Regine; Studer, Petra; Bock, Simon; Diedrichsen, Jörn; Goebel, Rainer; Mathiak, Klaus; Birbaumer, Niels; Weiskopf, Nikolaus

2015-05-01

Task performance depends on ongoing brain activity which can be influenced by attention, arousal, or motivation. However, such modulating factors of cognitive efficiency are unspecific, can be difficult to control, and are not suitable to facilitate neural processing in a regionally specific manner. Here, we non-pharmacologically manipulated regionally specific brain activity using technically sophisticated real-time fMRI neurofeedback. This was accomplished by training participants to simultaneously control ongoing brain activity in circumscribed motor and memory-related brain areas, namely the supplementary motor area and the parahippocampal cortex. We found that learned voluntary control over these functionally distinct brain areas caused functionally specific behavioral effects, i.e. shortening of motor reaction times and specific interference with memory encoding. The neurofeedback approach goes beyond improving cognitive efficiency by unspecific psychological factors such as attention, arousal, or motivation. It allows for directly manipulating sustained activity of task-relevant brain regions in order to yield specific behavioral or cognitive effects. Copyright © 2015 The Authors. Published by Elsevier B.V. All rights reserved.

Robust Real-Time Tracking for Visual Surveillance

Directory of Open Access Journals (Sweden)

Aguilera Josep

2007-01-01

Full Text Available This paper describes a real-time multi-camera surveillance system that can be applied to a range of application domains. This integrated system is designed to observe crowded scenes and has mechanisms to improve tracking of objects that are in close proximity. The four component modules described in this paper are (i motion detection using a layered background model, (ii object tracking based on local appearance, (iii hierarchical object recognition, and (iv fused multisensor object tracking using multiple features and geometric constraints. This integrated approach to complex scene tracking is validated against a number of representative real-world scenarios to show that robust, real-time analysis can be performed.

Statistical quality analysis of schedulers under soft-real-time constraints

NARCIS (Netherlands)

Baarsma, H.E.; Hurink, Johann L.; Jansen, P.G.

2007-01-01

This paper describes an algorithm to determine the performance of real-time systems with tasks using stochastic processing times. Such an algorithm can be used for guaranteeing Quality of Service of periodic tasks with soft real-time constraints. We use a discrete distribution model of processing

Designing a fuzzy scheduler for hard real-time systems

Science.gov (United States)

Yen, John; Lee, Jonathan; Pfluger, Nathan; Natarajan, Swami

1992-01-01

In hard real-time systems, tasks have to be performed not only correctly, but also in a timely fashion. If timing constraints are not met, there might be severe consequences. Task scheduling is the most important problem in designing a hard real-time system, because the scheduling algorithm ensures that tasks meet their deadlines. However, the inherent nature of uncertainty in dynamic hard real-time systems increases the problems inherent in scheduling. In an effort to alleviate these problems, we have developed a fuzzy scheduler to facilitate searching for a feasible schedule. A set of fuzzy rules are proposed to guide the search. The situation we are trying to address is the performance of the system when no feasible solution can be found, and therefore, certain tasks will not be executed. We wish to limit the number of important tasks that are not scheduled.

Improving the Multi-Objective Performance of Rainwater Harvesting Systems Using Real-Time Control Technology

Directory of Open Access Journals (Sweden)

Wei D. Xu

2018-02-01

Full Text Available Many studies have identified the potential of rainwater harvesting (RWH systems to simultaneously augment potable water supply and reduce delivery of uncontrolled stormwater flows to downstream drainage networks. Potentially, such systems could also play a role in the controlled delivery of water to urban streams in ways which mimic baseflows. The performance of RWH systems to achieve these three objectives could be enhanced using Real-Time Control (RTC technology to receive rainfall forecasts and initiate pre-storm release in real time, although few studies have explored such potential. We used continuous simulation to model the ability of a range of allotment-scale RWH systems to simultaneously deliver: (i water supply; (ii stormwater retention; and (iii baseflow restoration. We compared the performance of RWH systems with RTC technology to conventional RWH systems and also systems designed with a passive baseflow release, rather than the active (RTC configuration. We found that RWH systems employing RTC technology were generally superior in simultaneously achieving water supply, stormwater retention and baseflow restoration benefits compared with the other types of system tested. The active operation provided by RTC allows the system to perform optimally across a wider range of climatic conditions, but needs to be carefully designed. We conclude that the active release mechanism employing RTC technology exhibits great promise; its ability to provide centralised control and failure detection also opens the possibility of delivering a more reliable rainwater harvesting system, which can be readily adapted to varying climate over both the short and long term.

Real-time software for the COMPASS tokamak plasma control

International Nuclear Information System (INIS)

Valcarcel, D.F.; Duarte, A.S.; Neto, A.; Carvalho, I.S.; Carvalho, B.B.; Fernandes, H.; Sousa, J.; Sartori, F.; Janky, F.; Cahyna, P.; Hron, M.; Panek, R.

2010-01-01

The COMPASS tokamak has started its operation recently in Prague and to meet the necessary operation parameters its real-time system, for data processing and control, must be designed for both flexibility and performance, allowing the easy integration of code from several developers and to guarantee the desired time cycle. For this purpose an Advanced Telecommunications Computing Architecture based real-time system has been deployed with a solution built on a multi-core x86 processor. It makes use of two software components: the BaseLib2 and the MARTe (Multithreaded Application Real-Time executor) real-time frameworks. The BaseLib2 framework is a generic real-time library with optimized objects for the implementation of real-time algorithms. This allowed to build a library of modules that process the acquired data and execute control algorithms. MARTe executes these modules in kernel space Real-Time Application Interface allowing to attain the required cycle time and a jitter of less than 1.5 μs. MARTe configuration and data storage are accomplished through a Java hardware client that connects to the FireSignal control and data acquisition software. This article details the implementation of the real-time system for the COMPASS tokamak, in particular the organization of the control code, the design and implementation of the communications with the actuators and how MARTe integrates with the FireSignal software.

Real-time software for the COMPASS tokamak plasma control

Energy Technology Data Exchange (ETDEWEB)

Valcarcel, D.F., E-mail: danielv@ipfn.ist.utl.p [Associacao EURATOM/IST, Instituto de Plasmas e Fusao Nuclear - Laboratorio Associado, Instituto Superior Tecnico, P-1049-001 Lisboa (Portugal); Duarte, A.S.; Neto, A.; Carvalho, I.S.; Carvalho, B.B.; Fernandes, H.; Sousa, J. [Associacao EURATOM/IST, Instituto de Plasmas e Fusao Nuclear - Laboratorio Associado, Instituto Superior Tecnico, P-1049-001 Lisboa (Portugal); Sartori, F. [Euratom-UKAEA, Culham Science Centre, Abingdon, OX14 3DB Oxon (United Kingdom); Janky, F.; Cahyna, P.; Hron, M.; Panek, R. [Institute of Plasma Physics AS CR, v.v.i., Association EURATOM/IPP.CR, Za Slovankou 3, 182 00 Prague (Czech Republic)

2010-07-15

The COMPASS tokamak has started its operation recently in Prague and to meet the necessary operation parameters its real-time system, for data processing and control, must be designed for both flexibility and performance, allowing the easy integration of code from several developers and to guarantee the desired time cycle. For this purpose an Advanced Telecommunications Computing Architecture based real-time system has been deployed with a solution built on a multi-core x86 processor. It makes use of two software components: the BaseLib2 and the MARTe (Multithreaded Application Real-Time executor) real-time frameworks. The BaseLib2 framework is a generic real-time library with optimized objects for the implementation of real-time algorithms. This allowed to build a library of modules that process the acquired data and execute control algorithms. MARTe executes these modules in kernel space Real-Time Application Interface allowing to attain the required cycle time and a jitter of less than 1.5 {mu}s. MARTe configuration and data storage are accomplished through a Java hardware client that connects to the FireSignal control and data acquisition software. This article details the implementation of the real-time system for the COMPASS tokamak, in particular the organization of the control code, the design and implementation of the communications with the actuators and how MARTe integrates with the FireSignal software.

Lineage-Specific Real-Time RT-PCR for Yellow Fever Virus Outbreak Surveillance, Brazil.

Science.gov (United States)

Fischer, Carlo; Torres, Maria C; Patel, Pranav; Moreira-Soto, Andres; Gould, Ernest A; Charrel, Rémi N; de Lamballerie, Xavier; Nogueira, Rita Maria Ribeiro; Sequeira, Patricia C; Rodrigues, Cintia D S; Kümmerer, Beate M; Drosten, Christian; Landt, Olfert; Bispo de Filippis, Ana Maria; Drexler, Jan Felix

2017-11-01

The current yellow fever outbreak in Brazil prompted widespread yellow fever virus (YFV) vaccination campaigns, imposing a responsibility to distinguish between vaccine- and wild-type YFV-associated disease. We developed novel multiplex real-time reverse transcription PCRs that differentiate between vaccine and American wild-type YFV. We validated these highly specific and sensitive assays in an outbreak setting.

Lineage-Specific Real-Time RT-PCR for Yellow Fever Virus Outbreak Surveillance, Brazil

OpenAIRE

Fischer, Carlo; Torres, Maria C.; Patel, Pranav; Moreira-Soto, Andres; Gould, Ernest A.; Charrel, Rémi N.; de Lamballerie, Xavier; Nogueira, Rita Maria Ribeiro; Sequeira, Patricia C.; Rodrigues, Cintia D.S.; Kümmerer, Beate M.; Drosten, Christian; Landt, Olfert; Bispo de Filippis, Ana Maria; Drexler, Jan Felix

2017-01-01

The current yellow fever outbreak in Brazil prompted widespread yellow fever virus (YFV) vaccination campaigns, imposing a responsibility to distinguish between vaccine- and wild-type YFV-associated disease. We developed novel multiplex real-time reverse transcription PCRs that differentiate between vaccine and American wild-type YFV. We validated these highly specific and sensitive assays in an outbreak setting.

A Real-Time Semiautonomous Audio Panning System for Music Mixing

Directory of Open Access Journals (Sweden)

Perez_Gonzalez Enrique

2010-01-01

Full Text Available A real-time semiautonomous stereo panning system for music mixing has been implemented. The system uses spectral decomposition, constraint rules, and cross-adaptive algorithms to perform real-time placement of sources in a stereo mix. A subjective evaluation test was devised to evaluate its quality against human panning. It was shown that the automatic panning technique performed better than a nonexpert and showed no significant statistical difference to the performance of a professional mixing engineer.

Real-time FPGA architectures for computer vision

Science.gov (United States)

Arias-Estrada, Miguel; Torres-Huitzil, Cesar

2000-03-01

This paper presents an architecture for real-time generic convolution of a mask and an image. The architecture is intended for fast low level image processing. The FPGA-based architecture takes advantage of the availability of registers in FPGAs to implement an efficient and compact module to process the convolutions. The architecture is designed to minimize the number of accesses to the image memory and is based on parallel modules with internal pipeline operation in order to improve its performance. The architecture is prototyped in a FPGA, but it can be implemented on a dedicated VLSI to reach higher clock frequencies. Complexity issues, FPGA resources utilization, FPGA limitations, and real time performance are discussed. Some results are presented and discussed.

Real time equilibrium reconstruction for tokamak discharge control

International Nuclear Information System (INIS)

Ferron, J.R.; Walker, M.L.; Lao, L.L.; St John, H.E.; Humphreys, D.A.; Leuer, J.A.

1998-01-01

A practical method for performing a tokamak equilibrium reconstruction in real time for arbitrary time varying discharge shapes and current profiles is described. An approximate solution to the Grad-Shafranov equilibrium relation is found which best fits the diagnostic measurements. Thus, a solution for the spatial distribution of poloidal flux and toroidal current density is available in real time that is consistent with plasma force balance, allowing accurate evaluation of parameters such as discharge shape and safety factor profile. The equilibrium solutions are produced at a rate sufficient for discharge control. This equilibrium reconstruction algorithm has been implemented on the digital plasma control system for the DIII-D tokamak. The first application of real time equilibrium reconstruction to discharge shape control is described. (author)

Real Time Strategy Language

OpenAIRE

Hayes, Roy; Beling, Peter; Scherer, William

2014-01-01

Real Time Strategy (RTS) games provide complex domain to test the latest artificial intelligence (AI) research. In much of the literature, AI systems have been limited to playing one game. Although, this specialization has resulted in stronger AI gaming systems it does not address the key concerns of AI researcher. AI researchers seek the development of AI agents that can autonomously interpret learn, and apply new knowledge. To achieve human level performance, current AI systems rely on game...

Laboratory evaluation of a quantitative real-time reverse transcription PCR assay for the detection and identification of the four subgroups of avian metapneumovirus.

Science.gov (United States)

Guionie, O; Toquin, D; Sellal, E; Bouley, S; Zwingelstein, F; Allée, C; Bougeard, S; Lemière, S; Eterradossi, N

2007-02-01

Avian metapneumovirus (AMPV) is an important pathogen causing respiratory diseases and egg drops in several avian species. Four AMPV subgroups have been identified. The laboratory diagnosis of AMPV infections relies on serological methods, on labour-intensive virus isolation procedures, and on recently developed subgroup specific reverse transcription PCR (RT-PCR) protocols. In the present study, both the specificity and sensitivity of a commercial real-time reverse transcription PCR (RRT-PCR) for the detection and identification of the four AMPV subgroups were evaluated. Fifteen non-AMPV avian viruses belonging to 7 genera and 32 AMPV belonging to the 4 subgroups were tested. No non-AMPV virus was detected, whereas all AMPV viruses were identified in agreement with their previous molecular and antigenic subgroup assignment. The sensitivity and quantitating ability of the RRT-PCR assay were determined using serial dilutions of RNA derived either from AMPV virus stocks or from runoff transcripts. In all cases, linear dose/responses were observed. The detection limits of the different subgroups ranged from 500 to 5000 RNA copies and from 0.03 to 3.16TCID50/ml. The results were reproducible under laboratory conditions, thus showing that quantitative RRT-PCR is a new and powerful tool for the rapid and sensitive detection, identification and quantitation of AMPVs.

Application of a Real-time Reverse Transcription Loop Mediated Amplification Method to the Detection of Rabies Virus in Arctic Foxes in Greenland

DEFF Research Database (Denmark)

Wakeley, Philip; Johnson, Nicholas; Rasmussen, Thomas Bruun

Reverse transcription loop mediated amplification (RT-LAMP) offers a rapid, isothermal method for amplification of virus RNA. In this study a panel of positive rabies virus samples originally prepared from arctic fox brain tissue was assessed for the presence of rabies viral RNA using a real time...... RT-LAMP. The method had previously been shown to work with samples from Ghana which clustered with cosmopolitan lineage rabies viruses but the assay had not been assessed using samples from animals infected with rabies from the arctic region. The assay is designed to amplify both cosmopolitan strains...... and arctic-like strains of classical rabies virus due to the primer design and is therefore expected to be universally applicable independent of region of the world where the virus is isolated. Of the samples tested all were found to be positive after incubation for 25 to 30 minutes. The method made use...

Essays in real-time forecasting

OpenAIRE

Liebermann, Joelle

2012-01-01

This thesis contains three essays in the field of real-time econometrics, and more particularlyforecasting.The issue of using data as available in real-time to forecasters, policymakers or financialmarkets is an important one which has only recently been taken on board in the empiricalliterature. Data available and used in real-time are preliminary and differ from ex-postrevised data, and given that data revisions may be quite substantial, the use of latestavailable instead of real-time can s...

MonoSLAM: real-time single camera SLAM.

Science.gov (United States)

Davison, Andrew J; Reid, Ian D; Molton, Nicholas D; Stasse, Olivier

2007-06-01

We present a real-time algorithm which can recover the 3D trajectory of a monocular camera, moving rapidly through a previously unknown scene. Our system, which we dub MonoSLAM, is the first successful application of the SLAM methodology from mobile robotics to the "pure vision" domain of a single uncontrolled camera, achieving real time but drift-free performance inaccessible to Structure from Motion approaches. The core of the approach is the online creation of a sparse but persistent map of natural landmarks within a probabilistic framework. Our key novel contributions include an active approach to mapping and measurement, the use of a general motion model for smooth camera movement, and solutions for monocular feature initialization and feature orientation estimation. Together, these add up to an extremely efficient and robust algorithm which runs at 30 Hz with standard PC and camera hardware. This work extends the range of robotic systems in which SLAM can be usefully applied, but also opens up new areas. We present applications of MonoSLAM to real-time 3D localization and mapping for a high-performance full-size humanoid robot and live augmented reality with a hand-held camera.

Plane-wave least-squares reverse-time migration

KAUST Repository

Dai, Wei

2013-06-03

A plane-wave least-squares reverse-time migration (LSRTM) is formulated with a new parameterization, where the migration image of each shot gather is updated separately and an ensemble of prestack images is produced along with common image gathers. The merits of plane-wave prestack LSRTM are the following: (1) plane-wave prestack LSRTM can sometimes offer stable convergence even when the migration velocity has bulk errors of up to 5%; (2) to significantly reduce computation cost, linear phase-shift encoding is applied to hundreds of shot gathers to produce dozens of plane waves. Unlike phase-shift encoding with random time shifts applied to each shot gather, plane-wave encoding can be effectively applied to data with a marine streamer geometry. (3) Plane-wave prestack LSRTM can provide higher-quality images than standard reverse-time migration. Numerical tests on the Marmousi2 model and a marine field data set are performed to illustrate the benefits of plane-wave LSRTM. Empirical results show that LSRTM in the plane-wave domain, compared to standard reversetime migration, produces images efficiently with fewer artifacts and better spatial resolution. Moreover, the prestack image ensemble accommodates more unknowns to makes it more robust than conventional least-squares migration in the presence of migration velocity errors. © 2013 Society of Exploration Geophysicists.

Real-time C++ efficient object-oriented and template microcontroller programming

CERN Document Server

Kormanyos, Christopher

2013-01-01

This is a highly practical guide to programming real-time embedded microcontroller systems in C++. Its many examples are backed by real-time performance measurements and size analyses that quantify the true cost of the code to the last byte and microsecond.

Real time control of plasmas and ECRH systems on TCV

NARCIS (Netherlands)

Paley, J.I.; Berrino, J.; Coda, S.; Cruz, N.; Duval, B.P.; Felici, F.; Goodman, T.P.; Martin, Y.; Moret, J.-M.; Piras, F.; Rodriques, A.P.; Santos, B.; Varandas, C.A.F.

2009-01-01

Developments in the real time control hardware on Tokamak Configuration Variable (TCV) coupled with the flexibility of plasma shaping and electron cyclotron (EC) heating and current drive actuators are opening many opportunities to perform real time experiments and develop algorithms and methods for

ArControl: An Arduino-Based Comprehensive Behavioral Platform with Real-Time Performance.

Science.gov (United States)

Chen, Xinfeng; Li, Haohong

2017-01-01

Studying animal behavior in the lab requires reliable delivering stimulations and monitoring responses. We constructed a comprehensive behavioral platform (ArControl: Arduino Control Platform) that was an affordable, easy-to-use, high-performance solution combined software and hardware components. The hardware component was consisted of an Arduino UNO board and a simple drive circuit. As for software, the ArControl provided a stand-alone and intuitive GUI (graphical user interface) application that did not require users to master scripts. The experiment data were automatically recorded with the built in DAQ (data acquisition) function. The ArControl also allowed the behavioral schedule to be entirely stored in and operated on the Arduino chip. This made the ArControl a genuine, real-time system with high temporal resolution (<1 ms). We tested the ArControl, based on strict performance measurements and two mice behavioral experiments. The results showed that the ArControl was an adaptive and reliable system suitable for behavioral research.

Real time processor for array speckle interferometry

Science.gov (United States)

Chin, Gordon; Florez, Jose; Borelli, Renan; Fong, Wai; Miko, Joseph; Trujillo, Carlos

1989-02-01

The authors are constructing a real-time processor to acquire image frames, perform array flat-fielding, execute a 64 x 64 element two-dimensional complex FFT (fast Fourier transform) and average the power spectrum, all within the 25 ms coherence time for speckles at near-IR (infrared) wavelength. The processor will be a compact unit controlled by a PC with real-time display and data storage capability. This will provide the ability to optimize observations and obtain results on the telescope rather than waiting several weeks before the data can be analyzed and viewed with offline methods. The image acquisition and processing, design criteria, and processor architecture are described.

Comparison of the analytical and clinical performances of Abbott RealTime High Risk HPV, Hybrid Capture 2, and DNA Chip assays in gynecology patients.

Science.gov (United States)

Park, Seungman; Kang, Youjin; Kim, Dong Geun; Kim, Eui-Chong; Park, Sung Sup; Seong, Moon-Woo

2013-08-01

The detection of high-risk (HR) HPV in cervical cancer screening is important for early diagnosis of cervical cancer or pre-cancerous lesions. We evaluated the analytical and clinical performances of 3 HR HPV assays in Gynecology patients. A total of 991 specimens were included in this study: 787 specimens for use with a Hybrid Capture 2 (HC2) and 204 specimens for a HPV DNA microarray (DNA Chip). All specimens were tested using an Abbott RealTime High Risk HPV assay (Real-time HR), PGMY PCR, and sequence analysis. Clinical sensitivities for severe abnormal cytology (severe than high-grade squamous intraepithelial lesion) were 81.8% for Real-time HR, 77.3% for HC2, and 66.7% for DNA Chip, and clinical sensitivities for severe abnormal histology (cervical intraepithelial neoplasia grade 2+) were 91.7% for HC2, 87.5% for Real-time HR, and 73.3% for DNA Chip. As compared to results of the sequence analysis, HC2, Real-time HR, and DNA Chip showed concordance rates of 94.3% (115/122), 90.0% (117/130), and 61.5% (16/26), respectively. The HC2 assay and Real-time HR assay showed comparable results to each other in both clinical and analytical performances, while the DNA Chip assay showed poor clinical and analytical performances. The Real-time HR assay can be a good alternative option for HR HPV testing with advantages of allowing full automation and simultaneous genotyping of HR types 16 and 18. Copyright © 2013 Elsevier Inc. All rights reserved.

Real Time Structured Light and Applications

DEFF Research Database (Denmark)

Wilm, Jakob

Structured light scanning is a versatile method for 3D shape acquisition. While much faster than most competing measurement techniques, most high-end structured light scans still take in the order of seconds to complete. Low-cost sensors such as Microsoft Kinect and time of flight cameras have made......, increased processing power, and methods presented in this thesis, it is possible to perform structured light scans in real time with 20 depth measurements per second. This offers new opportunities for studying dynamic scenes, quality control, human-computer interaction and more. This thesis discusses...... several aspects of real time structured light systems and presents contributions within calibration, scene coding and motion correction aspects. The problem of reliable and fast calibration of such systems is addressed with a novel calibration scheme utilising radial basis functions [Contribution B...

Real Time Supervisors and Monitors for Performing Health Monitoring and Fault Detection for Systems Operating in Multiple Regimes

National Research Council Canada - National Science Library

Jaw, Link

2003-01-01

In this Phase I STTR, SMI and ARL have developed a Real Time Supervisor for fault detection and system reconfiguration in a team of micro UAVs, that are tasked to perform a team mission like surveillance or rendezvous...

Real-time reverse transcription-polymerase chain reaction assays for identification of wild poliovirus 1 & 3.

Science.gov (United States)

Sharma, Deepa K; Nalavade, Uma P; Deshpande, Jagadish M

2015-10-01

The poliovirus serotype identification and intratypic differentiation by real-time reverse transcription-polymerase chain reaction (rRT-PCR) assay is suitable for serotype mixtures but not for intratypic mixtures of wild and vaccine poliovirus strains. This study was undertaken to develop wild poliovirus 1 and 3 (WPV1 and WPV3) specific rRT-PCR assays for use. Specific primers and probes for rRT-PCR were designed based on VP1 sequences of WPV1 and WPV3 isolated in India since 2000. The specificity of the rRT-PCR assays was evaluated using WPV1 and WPV3 of different genetic lineages, non-polio enteroviruses (NPEVs) and mixtures of wild/wild and wild/Sabin vaccine strains. The sensitivity of the assays was determined by testing serial 10-fold dilutions of wild poliovirus 1 and 3 stock suspensions of known titre. No cross-reactivity with Sabin strains, intertypic wild poliovirus isolates or 27 types of NPEVs across all the four Enterovirus species was found for both the wild poliovirus 1 and 3 rRT-PCR assays. All WPV1 and WPV3 strains isolated since 2000 were successfully amplified. The rRT-PCR assays detected 10 4.40 CCID 50 /ml of WPV1 and 10 4.00 CCID 50 /ml of WPV3, respectively either as single isolate or mixture with Sabin vaccine strains or intertypic wild poliovirus. rRT-PCR assays for WPV1 and WPV3 have been validated to detect all the genetic variations of the WPV1 and WPV3 isolated in India for the last decade. When used in combination with the current rRT-PCR assay testing was complete for confirmation of the presence of wild poliovirus in intratypic mixtures.

LHCb's Time-Real Alignment in RunII

CERN Multimedia

Batozskaya, Varvara

2015-01-01

LHCb has introduced a novel real-time detector alignment and calibration strategy for LHC Run 2. Data collected at the start of the fill will be processed in a few minutes and used to update the alignment, while the calibration constants will be evaluated for each run. This procedure will improve the quality of the online alignment. Critically, this new real-time alignment and calibration procedure allows identical constants to be used in the online and offline reconstruction, thus improving the correlation between triggered and offline selected events. This offers the opportunity to optimise the event selection in the trigger by applying stronger constraints. The required computing time constraints are met thanks to a new dedicated framework using the multi-core farm infrastructure for the trigger. The motivation for a real-time alignment and calibration of the LHCb detector is discussed from both the operational and physics performance points of view. Specific challenges of this novel configur...

Ovation Prime Real-Time

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The Ovation Prime Real-Time (OPRT) product is a real-time forecast and nowcast model of auroral power and is an operational implementation of the work by Newell et...

Real time control of plasmas and ECRH systems on TCV

NARCIS (Netherlands)

Paley, J.I.; Felici, F.; Berrino, J.; Coda, S.; Cruz, N.; Duval, B.P.; Goodman, T.P.; Martin, Y.; Moret, J.-M.; Piras, F.; Rodrigues, A.P.; Santos, B.; Varandas, C.A.F.

2008-01-01

Developments in the real time control hardware on TCV paired with the flexibility of plasma shaping and ECRH actuators are opening many opportunities to perform real time experiments and develop algorithms and methods for fusion applications. The ability to control MHD instabilities is particularly

Improved Safety for Molecular Diagnosis of Classical Rabies Viruses by Use of a TaqMan Real-Time Reverse Transcription-PCR "Double Check" Strategy

DEFF Research Database (Denmark)

Hoffmann, B.; Freuling, C. M.; Wakeley, P. R.

2010-01-01

To improve the diagnosis of classical rabies virus with molecular methods, a validated, ready-to-use, real-time reverse transcription-PCR (RT-PCR) assay was developed. In a first step, primers and 6-carboxyfluorescien-labeled TaqMan probes specific for rabies virus were selected from the consensus...... sequence of the nucleoprotein gene of 203 different rabies virus sequences derived from GenBank. The selected primer-probe combination was highly specific and sensitive. During validation using a sample set of rabies virus strains from the virus archives of the Friedrich-Loeffler-Institut (FLI; Germany......), the Veterinary Laboratories Agency (VLA; United Kingdom), and the DTU National Veterinary Institute (Lindholm, Denmark), covering the global diversity of rabies virus lineages, it was shown that both the newly developed assay and a previously described one had some detection failures. This was overcome...

Performance of real-time strain elastography, transient elastography, and aspartate-to-platelet ratio index in the assessment of fibrosis in chronic hepatitis C.

Science.gov (United States)

Ferraioli, Giovanna; Tinelli, Carmine; Malfitano, Antonello; Dal Bello, Barbara; Filice, Gaetano; Filice, Carlo; Above, Elisabetta; Barbarini, Giorgio; Brunetti, Enrico; Calderon, Willy; Di Gregorio, Marta; Lissandrin, Raffaella; Ludovisi, Serena; Maiocchi, Laura; Michelone, Giuseppe; Mondelli, Mario; Patruno, Savino F A; Perretti, Alessandro; Poma, Gianluigi; Sacchi, Paolo; Zaramella, Marco; Zicchetti, Mabel

2012-07-01

The purpose of this article is to evaluate the diagnostic performance of transient elastography, real-time strain elastography, and aspartate-to-platelet ratio index in assessing fibrosis in patients with chronic hepatitis C by using histologic Metavir scores as reference standard. Consecutive patients with chronic hepatitis C scheduled for liver biopsy were enrolled. Liver biopsy was performed on the same day as transient elastography and real-time strain elastography. Transient elastography and real-time strain elastography were performed in the same patient encounter by a single investigator using a medical device based on elastometry and an ultrasound machine, respectively. Diagnostic performance was assessed by using receiver operating characteristic curves and area under the receiver operating characteristic curve (AUC) analysis. One hundred thirty patients (91 men and 39 women) were analyzed. The cutoff values for transient elastography, real-time strain elastography, and aspartate-to-platelet ratio index were 6.9 kPa, 1.82, and 0.37, respectively, for fibrosis score of 2 or higher; 7.3 kPa, 1.86, and 0.70, respectively, for fibrosis score of 3 or higher; and 9.3 kPa, 2.33, and 0.70, respectively, for fibrosis score of 4. AUC values of transient elastography, real-time strain elastography, aspartate-to-platelet ratio index were 0.88, 0.74, and 0.86, respectively, for fibrosis score of 2 or higher; 0.95, 0.80, and 0.89, respectively, for fibrosis score of 3 or higher; and 0.97, 0.80, and 0.84, respectively, for fibrosis score of 4. A combination of the three methods, when two of three were in agreement, showed AUC curves of 0.93, 0.95, and 0.95 for fibrosis scores of 2 or higher, 3 or higher, and 4, respectively. Transient elastography, real-time strain elastography, and aspartate-to-platelet ratio index values were correlated with histologic stages of fibrosis. Transient elastography offered excellent diagnostic performance in assessing severe fibrosis and

Comparison of the Diagnostic Value Between Real-Time Reverse Transcription-Polymerase Chain Reaction Assay and Histopathologic Examination in Sentinel Lymph Nodes for Patients With Gastric Carcinoma.

Science.gov (United States)

Kwak, Yoonjin; Nam, Soo Kyung; Shin, Eun; Ahn, Sang-Hoon; Lee, Hee Eun; Park, Do Joong; Kim, Woo Ho; Kim, Hyung-Ho; Lee, Hye Seung

2016-05-01

Sentinel lymph node (SLN)-based diagnosis in gastric cancers has shown varied sensitivities and false-negative rates in several studies. Application of the reverse transcription-polymerase chain reaction (RT-PCR) in SLN diagnosis has recently been proposed. A total of 155 SLNs from 65 patients with cT1-2, N0 gastric cancer were examined. The histopathologic results were compared with results obtained by real-time RT-PCR for detecting molecular RNA (mRNA) of cytokeratin (CK)19, carcinoembryonic antigen (CEA), and CK20. The sensitivity and specificity of the multiple marker RT-PCR assay standardized against the results of the postoperative histological examination were 0.778 (95% confidence interval [CI], 0.577-0.914) and 0.781 (95% CI, 0.700-0.850), respectively. In comparison, the sensitivity and specificity of intraoperative diagnosis were 0.819 (95% CI, 0.619-0.937) and 1.000 (95% CI, 0.972-1.000), respectively. The positive predictive value of the multiple-marker RT-PCR assay was 0.355 (95% CI, 0.192-0.546) for predicting non-SLN metastasis, which was lower than that of intraoperative diagnosis (0.813, 95% CI, 0.544-0.960). The real-time RT-PCR assay could detect SLN metastasis in gastric cancer. However, the predictive value of the real-time RT-PCR assay was lower than that of precise histopathologic examination and did not outweigh that of our intraoperative SLN diagnosis. © American Society for Clinical Pathology, 2016. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Real time analysis under EDS

International Nuclear Information System (INIS)

Schneberk, D.

1985-07-01

This paper describes the analysis component of the Enrichment Diagnostic System (EDS) developed for the Atomic Vapor Laser Isotope Separation Program (AVLIS) at Lawrence Livermore National Laboratory (LLNL). Four different types of analysis are performed on data acquired through EDS: (1) absorption spectroscopy on laser-generated spectral lines, (2) mass spectrometer analysis, (3) general purpose waveform analysis, and (4) separation performance calculations. The information produced from this data includes: measures of particle density and velocity, partial pressures of residual gases, and overall measures of isotope enrichment. The analysis component supports a variety of real-time modeling tasks, a means for broadcasting data to other nodes, and a great degree of flexibility for tailoring computations to the exact needs of the process. A particular data base structure and program flow is common to all types of analysis. Key elements of the analysis component are: (1) a fast access data base which can configure all types of analysis, (2) a selected set of analysis routines, (3) a general purpose data manipulation and graphics package for the results of real time analysis. Each of these components are described with an emphasis upon how each contributes to overall system capability. 3 figs

VERSE - Virtual Equivalent Real-time Simulation

Science.gov (United States)

Zheng, Yang; Martin, Bryan J.; Villaume, Nathaniel

2005-01-01

Distributed real-time simulations provide important timing validation and hardware in the- loop results for the spacecraft flight software development cycle. Occasionally, the need for higher fidelity modeling and more comprehensive debugging capabilities - combined with a limited amount of computational resources - calls for a non real-time simulation environment that mimics the real-time environment. By creating a non real-time environment that accommodates simulations and flight software designed for a multi-CPU real-time system, we can save development time, cut mission costs, and reduce the likelihood of errors. This paper presents such a solution: Virtual Equivalent Real-time Simulation Environment (VERSE). VERSE turns the real-time operating system RTAI (Real-time Application Interface) into an event driven simulator that runs in virtual real time. Designed to keep the original RTAI architecture as intact as possible, and therefore inheriting RTAI's many capabilities, VERSE was implemented with remarkably little change to the RTAI source code. This small footprint together with use of the same API allows users to easily run the same application in both real-time and virtual time environments. VERSE has been used to build a workstation testbed for NASA's Space Interferometry Mission (SIM PlanetQuest) instrument flight software. With its flexible simulation controls and inexpensive setup and replication costs, VERSE will become an invaluable tool in future mission development.

Preliminary results on ghrelin mRNA quantification in buffalo calves during fasting and refeeding by real-time reverse transcription PCR assay

Directory of Open Access Journals (Sweden)

G. Neglia

2010-02-01

Full Text Available The aim of this trial was to evaluate ghrelin response to milk administration in 20 days old buffalo calves. The trial was carried out on 5 female buffalo calves with a mean age of 21.2±2.8 days. Five blood samples were collected from each animal into EDTA tubes, starting at 07.00 until 15.00, at 2-h intervals. At 09.00, after the second blood sample, replaced milk was administered to the calves. Blood samples were immediately placed at 4°C until processing, which was performed on the same day. We used real-time reverse transcription PCR system to detect the expression of ghrelin mRNA levels in blood of buffalo calves. Two calves showed a low ghrelin concentration at the start of the trial (Group A = low ghrelin concentration and three calves a high ghrelin concentration (Group B = high ghrelin concentration. Ghrelin expression was significantly higher either two hours (P<0.01 and just before feeding (P<0.05 in Group B vs. Group A. However, in both cases, a significant (P<0.05 difference was observed within each group between -2 and 6 hours after feeding. Therefore, ghrelin concentration tended to increase in animals that showed low levels and, similarly, it lowered in animals that showed high concentration. If these results will be confirmed, may represent the evidence that also in buffalo calves the ghrelin system may affect feed intake. Further studies are needed in order to better evaluate the ghrelin system in buffalo calves.

Visualization of swallowing using real-time TrueFISP MR fluoroscopy

Energy Technology Data Exchange (ETDEWEB)

Barkhausen, Joerg; Goyen, Mathias; Lauenstein, Thomas; Debatin, Joerg F. [Department of Diagnostic Radiology, University Hospital Essen (Germany); Winterfeld, F. von; Arweiler-Harbeck, Diana [Department of Otorhinolaryngology, University Hospital Essen (Germany)

2002-01-01

The aim of this study was to evaluate the ability of different real-time true fast imaging with steady precession (TrueFISP) sequences regarding their ability to depict the swallowing process and delineate oropharyngeal pathologies in patients with dysphagia. Real-time TrueFISP visualization of swallowing was performed in 8 volunteers and 6 patients with dysphagia using a 1.5 T scanner (Magnetom Sonata, Siemens, Erlangen Germany) equipped with high-performance gradients (amplitude 40 mT/m). Image quality of four different real-time TrueFISP sequences (TR 2.2-3.0 ms, TE 1.1-1.5 ms, matrix 63 x 128-135 x 256, field of view 250 mm{sup 2}, acquisition time per image 139-405 ms) was evaluated. Water, yoghurt, and semolina pudding were assessed as oral contrast agents. Functional exploration of the oropharyngeal apparatus was best possible using the fastest real-time TrueFISP sequence (TR 2.2 ms, TE 1.1 ms, matrix 63 x 128). Increased acquisition time resulted in blurring of anatomical structures. As the image contrast of TrueFISP sequences depends on T2/T1 properties, all tested foodstuff were well suited as oral contrast agents, but image quality was best using semolina pudding. Real-time visualization of swallowing is possible using real-time TrueFISP sequences in conjunction with oral contrast agents. For the functional exploration of swallowing high temporal resolution is more crucial than spatial resolution. (orig.)

Real-time systems design and analysis

CERN Document Server

Laplante, Phillip A

2004-01-01

"Real-Time Systems Design and Analysis, Third Edition is essential for students and practicing software engineers who want improved designs, faster computation, and ultimate cost savings. Chapters discuss hardware considerations and software requirements, software systems design, the software production process, performance estimation and optimization, and engineering considerations."--Jacket.

Performance of the new automated Abbott RealTime MTB assay for rapid detection of Mycobacterium tuberculosis complex in respiratory specimens.

Science.gov (United States)

Chen, J H K; She, K K K; Kwong, T-C; Wong, O-Y; Siu, G K H; Leung, C-C; Chang, K-C; Tam, C-M; Ho, P-L; Cheng, V C C; Yuen, K-Y; Yam, W-C

2015-09-01

The automated high-throughput Abbott RealTime MTB real-time PCR assay has been recently launched for Mycobacterium tuberculosis complex (MTBC) clinical diagnosis. This study would like to evaluate its performance. We first compared its diagnostic performance with the Roche Cobas TaqMan MTB assay on 214 clinical respiratory specimens. Prospective analysis of a total 520 specimens was then performed to further evaluate the Abbott assay. The Abbott assay showed a lower limit of detection at 22.5 AFB/ml, which was more sensitive than the Cobas assay (167.5 AFB/ml). The two assays demonstrated a significant difference in diagnostic performance (McNemar's test; P = 0.0034), in which the Abbott assay presented significantly higher area under curve (AUC) than the Cobas assay (1.000 vs 0.880; P = 0.0002). The Abbott assay demonstrated extremely low PCR inhibition on clinical respiratory specimens. The automated Abbott assay required only very short manual handling time (0.5 h), which could help to improve the laboratory management. In the prospective analysis, the overall estimates for sensitivity and specificity of the Abbott assay were both 100 % among smear-positive specimens, whereas the smear-negative specimens were 96.7 and 96.1 %, respectively. No cross-reactivity with non-tuberculosis mycobacterial species was observed. The superiority in sensitivity of the Abbott assay for detecting MTBC in smear-negative specimens could further minimize the risk in MTBC false-negative detection. The new Abbott RealTime MTB assay has good diagnostic performance which can be a useful diagnostic tool for rapid MTBC detection in clinical laboratories.

ISTTOK real-time architecture

Energy Technology Data Exchange (ETDEWEB)

Carvalho, Ivo S., E-mail: ivoc@ipfn.ist.utl.pt; Duarte, Paulo; Fernandes, Horácio; Valcárcel, Daniel F.; Carvalho, Pedro J.; Silva, Carlos; Duarte, André S.; Neto, André; Sousa, Jorge; Batista, António J.N.; Hekkert, Tiago; Carvalho, Bernardo B.

2014-03-15

Highlights: • All real-time diagnostics and actuators were integrated in the same control platform. • A 100 μs control cycle was achieved under the MARTe framework. • Time-windows based control with several event-driven control strategies implemented. • AC discharges with exception handling on iron core flux saturation. • An HTML discharge configuration was developed for configuring the MARTe system. - Abstract: The ISTTOK tokamak was upgraded with a plasma control system based on the Advanced Telecommunications Computing Architecture (ATCA) standard. This control system was designed to improve the discharge stability and to extend the operational space to the alternate plasma current (AC) discharges as part of the ISTTOK scientific program. In order to accomplish these objectives all ISTTOK diagnostics and actuators relevant for real-time operation were integrated in the control system. The control system was programmed in C++ over the Multi-threaded Application Real-Time executor (MARTe) which provides, among other features, a real-time scheduler, an interrupt handler, an intercommunications interface between code blocks and a clearly bounded interface with the external devices. As a complement to the MARTe framework, the BaseLib2 library provides the foundations for the data, code introspection and also a Hypertext Transfer Protocol (HTTP) server service. Taking advantage of the modular nature of MARTe, the algorithms of each diagnostic data processing, discharge timing, context switch, control and actuators output reference generation, run on well-defined blocks of code named Generic Application Module (GAM). This approach allows reusability of the code, simplified simulation, replacement or editing without changing the remaining GAMs. The ISTTOK control system GAMs run sequentially each 100 μs cycle on an Intel{sup ®} Q8200 4-core processor running at 2.33 GHz located in the ATCA crate. Two boards (inside the ATCA crate) with 32 analog

ISTTOK real-time architecture

International Nuclear Information System (INIS)

Carvalho, Ivo S.; Duarte, Paulo; Fernandes, Horácio; Valcárcel, Daniel F.; Carvalho, Pedro J.; Silva, Carlos; Duarte, André S.; Neto, André; Sousa, Jorge; Batista, António J.N.; Hekkert, Tiago; Carvalho, Bernardo B.

2014-01-01

Highlights: • All real-time diagnostics and actuators were integrated in the same control platform. • A 100 μs control cycle was achieved under the MARTe framework. • Time-windows based control with several event-driven control strategies implemented. • AC discharges with exception handling on iron core flux saturation. • An HTML discharge configuration was developed for configuring the MARTe system. - Abstract: The ISTTOK tokamak was upgraded with a plasma control system based on the Advanced Telecommunications Computing Architecture (ATCA) standard. This control system was designed to improve the discharge stability and to extend the operational space to the alternate plasma current (AC) discharges as part of the ISTTOK scientific program. In order to accomplish these objectives all ISTTOK diagnostics and actuators relevant for real-time operation were integrated in the control system. The control system was programmed in C++ over the Multi-threaded Application Real-Time executor (MARTe) which provides, among other features, a real-time scheduler, an interrupt handler, an intercommunications interface between code blocks and a clearly bounded interface with the external devices. As a complement to the MARTe framework, the BaseLib2 library provides the foundations for the data, code introspection and also a Hypertext Transfer Protocol (HTTP) server service. Taking advantage of the modular nature of MARTe, the algorithms of each diagnostic data processing, discharge timing, context switch, control and actuators output reference generation, run on well-defined blocks of code named Generic Application Module (GAM). This approach allows reusability of the code, simplified simulation, replacement or editing without changing the remaining GAMs. The ISTTOK control system GAMs run sequentially each 100 μs cycle on an Intel ® Q8200 4-core processor running at 2.33 GHz located in the ATCA crate. Two boards (inside the ATCA crate) with 32 analog

Evaluation of a multiplex real-time PCR assay for the detection of respiratory viruses in clinical specimens.

Science.gov (United States)

Rheem, Insoo; Park, Joowon; Kim, Tae-Hyun; Kim, Jong Wan

2012-11-01

In this study, we evaluated the analytical performance and clinical potential of a one-step multiplex real-time PCR assay for the simultaneous detection of 14 types of respiratory viruses using the AdvanSure RV real-time PCR Kit (LG Life Sciences, Korea). Three hundred and twenty clinical specimens were tested with the AdvanSure RV real-time PCR Kit and conventional multiplex reverse transcription (RT)-PCR assay. The assay results were analyzed and the one-step AdvanSure RV real-time PCR Kit was compared with the conventional multiplex RT-PCR assay with respect to the sensitivity and specificity of the detection of respiratory viruses. The limit of detection (LOD) was 1.31 plaque-forming units (PFU)/mL for human rhinoviruses (hRVs), 4.93 PFU/mL for human coronavirus HCoV-229E/NL63, 2.67 PFU/mL for human coronavirus HCoV-OC43, 18.20 PFU/mL for parainfluenza virus 1 (PIV)-1, 24.57 PFU/mL for PIV-2, 1.73 PFU/mL for PIV-3, 1.79 PFU/mL for influenza virus group (Flu) A, 59.51 PFU/mL for FluB, 5.46 PFU/mL for human respiratory syncytial virus (hRSV)-A, 17.23 PFU/mL for hRSV-B, 9.99 PFU/mL for human adenovirus (ADVs). The cross-reactivity test for this assay against 23 types of non-respiratory viruses showed negative results for all viruses tested. The agreement between the one-step AdvanSure multiplex real-time PCR assay and the conventional multiplex RT-PCR assay was 98%. The one-step AdvanSure RV multiplex real-time PCR assay is a simple assay with high potential for specific, rapid and sensitive laboratory diagnosis of respiratory viruses compared to conventional multiplex RT-PCR.

Time-reversal focusing of an expanding soliton gas in disordered replicas

KAUST Repository

Fratalocchi, Andrea; Armaroli, A.; Trillo, S.

2011-01-01

We investigate the properties of time reversibility of a soliton gas, originating from a dispersive regularization of a shock wave, as it propagates in a strongly disordered environment. An original approach combining information measures and spin glass theory shows that time-reversal focusing occurs for different replicas of the disorder in forward and backward propagation, provided the disorder varies on a length scale much shorter than the width of the soliton constituents. The analysis is performed by starting from a new class of reflectionless potentials, which describe the most general form of an expanding soliton gas of the defocusing nonlinear Schrödinger equation.

Time-reversal focusing of an expanding soliton gas in disordered replicas

KAUST Repository

Fratalocchi, Andrea

2011-05-31

We investigate the properties of time reversibility of a soliton gas, originating from a dispersive regularization of a shock wave, as it propagates in a strongly disordered environment. An original approach combining information measures and spin glass theory shows that time-reversal focusing occurs for different replicas of the disorder in forward and backward propagation, provided the disorder varies on a length scale much shorter than the width of the soliton constituents. The analysis is performed by starting from a new class of reflectionless potentials, which describe the most general form of an expanding soliton gas of the defocusing nonlinear Schrödinger equation.

A Novel Real-Time Feature Matching Scheme

Directory of Open Access Journals (Sweden)

Ying Liu

2014-02-01

Full Text Available Affine Scale Invariant Feature Transform (ASIFT can obtain fully affine invariance, however, its time cost reaches about twice that in Scale Invariant Feature Transform (SIFT. We propose an improved ASIFT algorithm based on feature points in scale space for real-time application. In order to detect the affine invariant feature point, we establish a second-order difference of Gaussian (DOG pyramid and replace the extreme detection in the DOG pyramid by zero detection in the proposed second-order DOG pyramid, which decreases the complexity of the scheme. Experimental results show that the proposed method has a big progress in the real-time performance compared to the traditional one, while preserving the fully affine invariance and precision.

Real Time Text Analysis

Science.gov (United States)

Senthilkumar, K.; Ruchika Mehra Vijayan, E.

2017-11-01

This paper aims to illustrate real time analysis of large scale data. For practical implementation we are performing sentiment analysis on live Twitter feeds for each individual tweet. To analyze sentiments we will train our data model on sentiWordNet, a polarity assigned wordNet sample by Princeton University. Our main objective will be to efficiency analyze large scale data on the fly using distributed computation. Apache Spark and Apache Hadoop eco system is used as distributed computation platform with Java as development language

Real-time position reconstruction with hippocampal place cells.

Science.gov (United States)

Guger, Christoph; Gener, Thomas; Pennartz, Cyriel M A; Brotons-Mas, Jorge R; Edlinger, Günter; Bermúdez I Badia, S; Verschure, Paul; Schaffelhofer, Stefan; Sanchez-Vives, Maria V

2011-01-01

Brain-computer interfaces (BCI) are using the electroencephalogram, the electrocorticogram and trains of action potentials as inputs to analyze brain activity for communication purposes and/or the control of external devices. Thus far it is not known whether a BCI system can be developed that utilizes the states of brain structures that are situated well below the cortical surface, such as the hippocampus. In order to address this question we used the activity of hippocampal place cells (PCs) to predict the position of an rodent in real-time. First, spike activity was recorded from the hippocampus during foraging and analyzed off-line to optimize the spike sorting and position reconstruction algorithm of rats. Then the spike activity was recorded and analyzed in real-time. The rat was running in a box of 80 cm × 80 cm and its locomotor movement was captured with a video tracking system. Data were acquired to calculate the rat's trajectories and to identify place fields. Then a Bayesian classifier was trained to predict the position of the rat given its neural activity. This information was used in subsequent trials to predict the rat's position in real-time. The real-time experiments were successfully performed and yielded an error between 12.2 and 17.4% using 5-6 neurons. It must be noted here that the encoding step was done with data recorded before the real-time experiment and comparable accuracies between off-line (mean error of 15.9% for three rats) and real-time experiments (mean error of 14.7%) were achieved. The experiment shows proof of principle that position reconstruction can be done in real-time, that PCs were stable and spike sorting was robust enough to generalize from the training run to the real-time reconstruction phase of the experiment. Real-time reconstruction may be used for a variety of purposes, including creating behavioral-neuronal feedback loops or for implementing neuroprosthetic control.

A hybrid condenser model for real-time applications in performance monitoring, control and optimization

International Nuclear Information System (INIS)

Ding Xudong; Cai Wenjian; Jia Lei; Wen Changyun; Zhang Guiqing

2009-01-01

In this paper, a simple, yet accurate hybrid modeling technique for condensers is presented. The method starts with fundamental physical principles but captures only few key operational characteristic parameters to predict the system performances. The advantages of the methods lie that linear or non-linear least-squares methods can be directly used to determine no more than four key operational characteristic parameters in the model, which can significantly reduce the computational burden. The developed model is verified with the experimental data taken from a pilot system. The testing results confirm that the proposed model can predict accurately the performance of the real-time operating condenser with the maximum error of less than ±10%. The model technique proposed will have wide applications not only in condenser operating optimization, but also in performance assessment and fault detection and diagnosis.

Accessible high performance computing solutions for near real-time image processing for time critical applications

Science.gov (United States)

Bielski, Conrad; Lemoine, Guido; Syryczynski, Jacek

2009-09-01

High Performance Computing (HPC) hardware solutions such as grid computing and General Processing on a Graphics Processing Unit (GPGPU) are now accessible to users with general computing needs. Grid computing infrastructures in the form of computing clusters or blades are becoming common place and GPGPU solutions that leverage the processing power of the video card are quickly being integrated into personal workstations. Our interest in these HPC technologies stems from the need to produce near real-time maps from a combination of pre- and post-event satellite imagery in support of post-disaster management. Faster processing provides a twofold gain in this situation: 1. critical information can be provided faster and 2. more elaborate automated processing can be performed prior to providing the critical information. In our particular case, we test the use of the PANTEX index which is based on analysis of image textural measures extracted using anisotropic, rotation-invariant GLCM statistics. The use of this index, applied in a moving window, has been shown to successfully identify built-up areas in remotely sensed imagery. Built-up index image masks are important input to the structuring of damage assessment interpretation because they help optimise the workload. The performance of computing the PANTEX workflow is compared on two different HPC hardware architectures: (1) a blade server with 4 blades, each having dual quad-core CPUs and (2) a CUDA enabled GPU workstation. The reference platform is a dual CPU-quad core workstation and the PANTEX workflow total computing time is measured. Furthermore, as part of a qualitative evaluation, the differences in setting up and configuring various hardware solutions and the related software coding effort is presented.

Improved Real-time Denoising Method Based on Lifting Wavelet Transform

Directory of Open Access Journals (Sweden)

Liu Zhaohua

2014-06-01

Full Text Available Signal denoising can not only enhance the signal to noise ratio (SNR but also reduce the effect of noise. In order to satisfy the requirements of real-time signal denoising, an improved semisoft shrinkage real-time denoising method based on lifting wavelet transform was proposed. The moving data window technology realizes the real-time wavelet denoising, which employs wavelet transform based on lifting scheme to reduce computational complexity. Also hyperbolic threshold function and recursive threshold computing can ensure the dynamic characteristics of the system, in addition, it can improve the real-time calculating efficiency as well. The simulation results show that the semisoft shrinkage real-time denoising method has quite a good performance in comparison to the traditional methods, namely soft-thresholding and hard-thresholding. Therefore, this method can solve more practical engineering problems.

A timed-automata approach for critical path detection in a soft real-time application

NARCIS (Netherlands)

Yildiz, Bugra Mehmet; Bockisch, Christoph; Rensink, Arend; Aksit, Mehmet

In this paper, we report preliminary ideas from our project called “Time Performance Improvement With Parallel Processing Systems‿ (TIPS). In the TIPS project, we plan to take advantage of multi-core platforms for performance improvement by parallelizing a complex soft real-time application. In

Rapid genome detection of Schmallenberg virus and bovine viral diarrhea virus by use of isothermal amplification methods and high-speed real-time reverse transcriptase PCR.

Science.gov (United States)

Aebischer, Andrea; Wernike, Kerstin; Hoffmann, Bernd; Beer, Martin

2014-06-01

Over the past few years, there has been an increasing demand for rapid and simple diagnostic tools that can be applied outside centralized laboratories by using transportable devices. In veterinary medicine, such mobile test systems would circumvent barriers associated with the transportation of samples and significantly reduce the time to diagnose important infectious animal diseases. Among a wide range of available technologies, high-speed real-time reverse transcriptase quantitative PCR (RT-qPCR) and the two isothermal amplification techniques loop-mediated isothermal amplification (LAMP) and recombinase polymerase amplification (RPA) represent three promising candidates for integration into mobile pen-side tests. The aim of this study was to investigate the performance of these amplification strategies and to evaluate their suitability for field application. In order to enable a valid comparison, novel pathogen-specific assays have been developed for the detection of Schmallenberg virus and bovine viral diarrhea virus. The newly developed assays were evaluated in comparison with established standard RT-qPCR using samples from experimentally or field-infected animals. Even though all assays allowed detection of the target virus in less than 30 min, major differences were revealed concerning sensitivity, specificity, robustness, testing time, and complexity of assay design. These findings indicated that the success of an assay will depend on the integrated amplification technology. Therefore, the application-specific pros and cons of each method that were identified during this study provide very valuable insights for future development and optimization of pen-side tests. Copyright © 2014, American Society for Microbiology. All Rights Reserved.

Facial Expression Emotion Detection for Real-Time Embedded Systems

Directory of Open Access Journals (Sweden)

Saeed Turabzadeh

2018-01-01

Full Text Available Recently, real-time facial expression recognition has attracted more and more research. In this study, an automatic facial expression real-time system was built and tested. Firstly, the system and model were designed and tested on a MATLAB environment followed by a MATLAB Simulink environment that is capable of recognizing continuous facial expressions in real-time with a rate of 1 frame per second and that is implemented on a desktop PC. They have been evaluated in a public dataset, and the experimental results were promising. The dataset and labels used in this study were made from videos, which were recorded twice from five participants while watching a video. Secondly, in order to implement in real-time at a faster frame rate, the facial expression recognition system was built on the field-programmable gate array (FPGA. The camera sensor used in this work was a Digilent VmodCAM — stereo camera module. The model was built on the Atlys™ Spartan-6 FPGA development board. It can continuously perform emotional state recognition in real-time at a frame rate of 30. A graphical user interface was designed to display the participant’s video in real-time and two-dimensional predict labels of the emotion at the same time.

Performance characteristics and comparison of Abbott and artus real-time systems for hepatitis B virus DNA quantification.

Science.gov (United States)

Ismail, Ashrafali M; Sivakumar, Jayashree; Anantharam, Raghavendran; Dayalan, Sujitha; Samuel, Prasanna; Fletcher, Gnanadurai J; Gnanamony, Manu; Abraham, Priya

2011-09-01

Virological monitoring of hepatitis B virus (HBV) DNA is critical to the management of HBV infection. With several HBV DNA quantification assays available, it is important to use the most efficient testing system for virological monitoring. In this study, we evaluated the performance characteristics and comparability of three HBV DNA quantification systems: Abbott HBV real-time PCR (Abbott PCR), artus HBV real-time PCR with QIAamp DNA blood kit purification (artus-DB), and artus HBV real-time PCR with the QIAamp DSP virus kit purification (artus-DSP). The lower limits of detection of these systems were established against the WHO international standards for HBV DNA and were found to be 1.43, 82, and 9 IU/ml, respectively. The intra-assay and interassay coefficients of variation of plasma samples (1 to 6 log(10) IU/ml) ranged between 0.05 to 8.34% and 0.16 to 3.48% for the Abbott PCR, 1.53 to 26.85% and 0.50 to 12.89% for artus-DB, and 0.29 to 7.42% and 0.94 to 3.01% for artus-DSP, respectively. Ninety HBV clinical samples were used for comparison of assays, and paired quantitative results showed strong correlation by linear regression analysis (artus-DB with Abbott PCR, r = 0.95; Abbott PCR with artus-DSP, r = 0.97; and artus-DSP with artus-DB, r = 0.94). Bland-Altman analysis showed a good level of agreement for Abbott PCR and artus-DSP, with a mean difference of 0.10 log(10) IU/ml and limits of agreement of -0.91 to 1.11 log(10) IU/ml. No genotype-specific bias was seen in all three systems for HBV genotypes A, C, and D, which are predominant in this region. This finding illustrates that the Abbott real-time HBV and artus-DSP systems show more comparable performance than the artus-DB system, meeting the current guidelines for assays to be used in the management of hepatitis B.

Performance of a real-time PCR assay in routine bovine mastitis diagnostics compared with in-depth conventional culture.

Science.gov (United States)

Hiitiö, Heidi; Riva, Rauna; Autio, Tiina; Pohjanvirta, Tarja; Holopainen, Jani; Pyörälä, Satu; Pelkonen, Sinikka

2015-05-01

Reliable identification of the aetiological agent is crucial in mastitis diagnostics. Real-time PCR is a fast, automated tool for detecting the most common udder pathogens directly from milk. In this study aseptically taken quarter milk samples were analysed with a real-time PCR assay (Thermo Scientific PathoProof Mastitis Complete-12 Kit, Thermo Fisher Scientific Ltd.) and by semi-quantitative, in-depth bacteriological culture (BC). The aim of the study was to evaluate the diagnostic performance of the real-time PCR assay in routine use. A total of 294 quarter milk samples from routine mastitis cases were cultured in the national reference laboratory of Finland and examined with real-time PCR. With BC, 251 out of 294 (85.7%) of the milk samples had at least one colony on the plate and 38 samples were considered contaminated. In the PCR mastitis assay, DNA of target species was amplified in 244 samples out of 294 (83.0%). The most common bacterial species detected in the samples, irrespective of the diagnostic method, was the coagulase negative staphylococci (CNS) group (later referred as Staphylococcus spp.) followed by Staphylococcus aureus. Sensitivity (Se) and specificity (Sp) for the PCR assay to provide a positive Staph. aureus result was 97.0 and 95.8% compared with BC. For Staphylococcus spp., the corresponding figures were 86.7 and 75.4%. Our results imply that PCR performed well as a diagnostic tool to detect Staph. aureus but may be too nonspecific for Staphylococcus spp. in routine use with the current cut-off Ct value (37.0). Using PCR as the only microbiological method for mastitis diagnostics, clinical relevance of the results should be carefully considered before further decisions, for instance antimicrobial treatment, especially when minor pathogens with low amount of DNA have been detected. Introducing the concept of contaminated samples should also be considered.

Upgrade of the COMPASS tokamak real-time control system

Energy Technology Data Exchange (ETDEWEB)

Janky, F., E-mail: filip.janky.work@gmail.com [Institute of Plasma Physics, AS CR, v.v.i., Association EURATOM/IPP.CR, Za Slovankou 3, 18200 Prague (Czech Republic); Charles University in Prague, Faculty of Mathematics and Physics, V Holesovickach 2, 18000 Prague (Czech Republic); Havlicek, J. [Institute of Plasma Physics, AS CR, v.v.i., Association EURATOM/IPP.CR, Za Slovankou 3, 18200 Prague (Czech Republic); Charles University in Prague, Faculty of Mathematics and Physics, V Holesovickach 2, 18000 Prague (Czech Republic); Batista, A.J.N. [Associação EURATOM/IST, Instituto de Plasmas e Fusão Nuclear, Instituto Superior Técnico, Universidade Técnica de Lisboa, 1049-001 Lisboa (Portugal); Kudlacek, O.; Seidl, J. [Institute of Plasma Physics, AS CR, v.v.i., Association EURATOM/IPP.CR, Za Slovankou 3, 18200 Prague (Czech Republic); Neto, A.C. [Associação EURATOM/IST, Instituto de Plasmas e Fusão Nuclear, Instituto Superior Técnico, Universidade Técnica de Lisboa, 1049-001 Lisboa (Portugal); Pipek, J.; Hron, M. [Institute of Plasma Physics, AS CR, v.v.i., Association EURATOM/IPP.CR, Za Slovankou 3, 18200 Prague (Czech Republic); Mikulin, O. [Institute of Plasma Physics, AS CR, v.v.i., Association EURATOM/IPP.CR, Za Slovankou 3, 18200 Prague (Czech Republic); Czech Technical University, Faculty of Nuclear Sciences and Physical Engineering, V Holesovickach 2, 18000 Prague (Czech Republic); and others

2014-03-15

Highlights: • An upgrade of the COMPASS real-time system has been made to generally improve the plasma performance. • Stability of discharges in SNT configuration has been increased. • Plasma flat-top phase length has been extended. • Central solenoid protection has been developed. • Plasma position estimation has been improved. - Abstract: The COMPASS plasma control system is based on the MARTe real-time framework. Thanks to MARTe modularity and flexibility new algorithms have been developed for plasma diagnostic (plasma position calculation), control (shaping field control), and protection systems (central solenoid protection). Moreover, the MARTe framework itself was modified to broaden the communication capabilities via Aurora. This paper presents the recent upgrades and improvements made to the COMPASS real-time plasma control system, focusing on the issues related to precision of the real-time calculations, and discussing the improvements in terms of discharge parameters and stability. In particular, the new real-time system has given the possibility to analyze and to minimize the transport delays of each control loop.

Architecture for dynamically reconfigurable real-time lossless compression

Science.gov (United States)

Carter, Alison J.; Audsley, Neil C.

2004-05-01

Image compression is a computationally intensive task, which can be undertaken most efficiently by dedicated hardware. If a portable device is to carry out real-time compression on a variety of image types, then it may be useful to reconfigure the circuitry dynamically. Using commercial off-the shelf (COTS) chips, reconfiguration is usually implemented by a complete re-load from memory, but it is also possible to perform a partial reconfiguration. This work studies the use of programmable hardware devices to implement the lossless JPEG compression algorithm in real-time on a stream of independent image frames. The data rate is faster than can be compressed serially in hardware by a single processor, so the operation is split amongst several processors. These are implemented as programmable circuits, together with necessary buffering of input and output data. The timing of input and output, bearing in mind the different, and context-dependent amounts of data due to Huffman coding, is analyzed using storage-timing graphs. Because there may be differing parameters from one frame to the next, several different configurations are prepared and stored, ready to load as required. The scheduling of these reconfigurations, and the distribution/recombination of data streams is studied, giving an analysis of the real-time performance.

Real-time luminescence from Al2O3 fiber dosimeters

International Nuclear Information System (INIS)

Polf, J.C.; Yukihara, E.G.; Akselrod, M.S.; McKeever, S.W.S.

2004-01-01

The real-time luminescence signal from Al 2 O 3 single crystal fibers, monitored during simultaneous irradiation and optical stimulation, was investigated using computer simulations and experimental measurements. Both radioluminescence (RL) and optically stimulated luminescence (OSL) signals were studied. The simulations were performed initially using a simple one-trap/one-recombination-center energy band model, and then extended to include shallow and deep electron traps as well. Real-time luminescence experiments were performed for different radiation dose rates and optical stimulation powers using periodic laser stimulation of the samples through a fiber optic cable, and the experimental results were compared with the predictions from the computer simulations. The luminescence signal was observed, both theoretically and experimentally, to increase from its initial value to a steady-state level. The steady-state RL and OSL levels were found to be dependent on dose rate, the steady-state level of the real-time OSL being independent of laser power. It was also shown that the total integrated absorbed dose throughout the irradiation period can be determined by correcting the real-time OSL signal for depletion caused by each laser stimulation pulse. The effects of the shallow and deep traps on the time-dependence of the real-time luminescence signal were studied comparing the experimental data from several Al 2 O 3 fibers known to have different trapping state concentrations. The additional traps were found to slow the response of the real-time luminescence such that the time to reach steady state was increased as the additional traps were added

Research and Realization of the HJ-1C Real-time Software Frame Synchronization Algorithm

Directory of Open Access Journals (Sweden)

Hou Yang-shuan

2014-06-01

Full Text Available Conventional software frame synchronization methods are inefficient in processing huge continuous data without synchronization words. To improve the processing speed, a real-time synchronization algorithm is proposed based on reverse searching. Satellite data are grouped and searched in the reverse direction to avoid searching for synchronization words in huge continuous invalid data; thus, the frame synchronization speed is improved enormously. The fastest processing speed is up to 15445.9 Mbps when HJ-1C data are tested. This method is presently applied to the HJ-1C quick-look system in remote sensing satellite ground stations.

A time reversal transmission approach for multi-user UWB communications

DEFF Research Database (Denmark)

Nguyen, Tuan Hung; Kovacs Z., Istvan; Eggers, Patrick

2005-01-01

In this paper we propose and evaluate the performance of the time reversal technique in impulse radio UWB communications. The evaluation was based on measured channel impulse responses in the UWB frequency band of 3 to 5 GHz of a 4x1 MISO system with both vertical and horizontal polarization at t...

Performance evaluation and modeling of a conformal filter (CF) based real-time standoff hazardous material detection sensor

Science.gov (United States)

Nelson, Matthew P.; Tazik, Shawna K.; Bangalore, Arjun S.; Treado, Patrick J.; Klem, Ethan; Temple, Dorota

2017-05-01

Hyperspectral imaging (HSI) systems can provide detection and identification of a variety of targets in the presence of complex backgrounds. However, current generation sensors are typically large, costly to field, do not usually operate in real time and have limited sensitivity and specificity. Despite these shortcomings, HSI-based intelligence has proven to be a valuable tool, thus resulting in increased demand for this type of technology. By moving the next generation of HSI technology into a more adaptive configuration, and a smaller and more cost effective form factor, HSI technologies can help maintain a competitive advantage for the U.S. armed forces as well as local, state and federal law enforcement agencies. Operating near the physical limits of HSI system capability is often necessary and very challenging, but is often enabled by rigorous modeling of detection performance. Specific performance envelopes we consistently strive to improve include: operating under low signal to background conditions; at higher and higher frame rates; and under less than ideal motion control scenarios. An adaptable, low cost, low footprint, standoff sensor architecture we have been maturing includes the use of conformal liquid crystal tunable filters (LCTFs). These Conformal Filters (CFs) are electro-optically tunable, multivariate HSI spectrometers that, when combined with Dual Polarization (DP) optics, produce optimized spectral passbands on demand, which can readily be reconfigured, to discriminate targets from complex backgrounds in real-time. With DARPA support, ChemImage Sensor Systems (CISS™) in collaboration with Research Triangle Institute (RTI) International are developing a novel, real-time, adaptable, compressive sensing short-wave infrared (SWIR) hyperspectral imaging technology called the Reconfigurable Conformal Imaging Sensor (RCIS) based on DP-CF technology. RCIS will address many shortcomings of current generation systems and offer improvements in

LHCb's Real-Time Alignment in Run2

CERN Multimedia

Batozskaya, Varvara

2015-01-01

Stable, precise spatial alignment and PID calibration are necessary to achieve optimal detector performances. During Run2, LHCb will have a new real-time detector alignment and calibration to reach equivalent performances in the online and offline reconstruction. This offers the opportunity to optimise the event selection by applying stronger constraints as well as hadronic particle identification at the trigger level. The required computing time constraints are met thanks to a new dedicated framework using the multi-core farm infrastructure for the trigger.

Real-time on a standard UNIX workstation?

International Nuclear Information System (INIS)

Glanzman, T.

1992-09-01

This is a report of an ongoing R ampersand D project which is investigating the use of standard UNIX workstations for the real-time data acquisition from a major new experimental initiative, the SLAC B Factory (PEP II). For this work an IBM RS/6000 workstation running the AIX operating system is used. Real-time extensions to the UNIX operating system are explored and performance measured. These extensions comprise a set of AIX-specific and POSIX-compliant system services. Benchmark comparisons are made with embedded processor technologies. Results are presented for a simple prototype on-line system for laboratory-testing of a new prototype drift chamber

Time-Reversal Generation of Rogue Waves

Science.gov (United States)

Chabchoub, Amin; Fink, Mathias

2014-03-01

The formation of extreme localizations in nonlinear dispersive media can be explained and described within the framework of nonlinear evolution equations, such as the nonlinear Schrödinger equation (NLS). Within the class of exact NLS breather solutions on a finite background, which describe the modulational instability of monochromatic wave trains, the hierarchy of rational solutions localized in both time and space is considered to provide appropriate prototypes to model rogue wave dynamics. Here, we use the time-reversal invariance of the NLS to propose and experimentally demonstrate a new approach to constructing strongly nonlinear localized waves focused in both time and space. The potential applications of this time-reversal approach include remote sensing and motivated analogous experimental analysis in other nonlinear dispersive media, such as optics, Bose-Einstein condensates, and plasma, where the wave motion dynamics is governed by the NLS.

Real-time numerical simulation of the Carnot cycle

International Nuclear Information System (INIS)

Hurkala, J; Gall, M; Kutner, R; Maciejczyk, M

2005-01-01

We developed a highly interactive, multi-windows Java applet which made it possible to simulate and visualize within any platform and internet the Carnot cycle (or engine) in a real-time computer experiment. We extended our previous model and algorithm (Galant et al 2003 Heat Transfer, Newton's Law of Cooling and the Law of Entropy Increase Simulated by the Real-Time Computer Experiments in Java (Lecture Notes in Computer Science vol 2657) pp 45-53, Gall and Kutner 2005 Molecular mechanisms of heat transfer: Debye relaxation versus power-law Physica A 352 347-78) to simulate not only the heat flow but also the macroscopic movement of the piston. Since in reality it is impossible to construct a reversible Carnot engine, the question arises whether it is possible to simulate it at least in a numerical experiment? The positive answer to this question which we found is related to our model and algorithm which make it possible to omit the many-body problem arising when many gas particles simultaneously interact with the mobile piston. As usual, the considerations of phenomenological thermodynamics began with a study of the basic properties of heat engines, hence our approach, besides intrinsic physical significance, is also important from the educational, technological and even environmental points of view

Design and Performance of the CDC Real-Time Reverse Transcriptase PCR Swine Flu Panel for Detection of 2009 A (H1N1) Pandemic Influenza Virus▿†‡

Science.gov (United States)

Shu, Bo; Wu, Kai-Hui; Emery, Shannon; Villanueva, Julie; Johnson, Roy; Guthrie, Erica; Berman, LaShondra; Warnes, Christine; Barnes, Nathelia; Klimov, Alexander; Lindstrom, Stephen

2011-01-01

Swine influenza viruses (SIV) have been shown to sporadically infect humans and are infrequently identified by the Influenza Division of the Centers for Disease Control and Prevention (CDC) after being received as unsubtypeable influenza A virus samples. Real-time reverse transcriptase PCR (rRT-PCR) procedures for detection and characterization of North American lineage (N. Am) SIV were developed and implemented at CDC for rapid identification of specimens from cases of suspected infections with SIV. These procedures were utilized in April 2009 for detection of human cases of 2009 A (H1N1) pandemic (pdm) influenza virus infection. Based on genetic sequence data derived from the first two viruses investigated, the previously developed rRT-PCR procedures were optimized to create the CDC rRT-PCR Swine Flu Panel for detection of the 2009 A (H1N1) pdm influenza virus. The analytical sensitivity of the CDC rRT-PCR Swine Flu Panel was shown to be 5 copies of RNA per reaction and 10−1.3∼−0.7 50% infectious doses (ID50) per reaction for cultured viruses. Cross-reactivity was not observed when testing human clinical specimens or cultured viruses that were positive for human seasonal A (H1N1, H3N2) and B influenza viruses. The CDC rRT-PCR Swine Flu Panel was distributed to public health laboratories in the United States and internationally from April 2009 until June 2010. The CDC rRT-PCR Swine Flu Panel served as an effective tool for timely and specific detection of 2009 A (H1N1) pdm influenza viruses and facilitated subsequent public health response implementation. PMID:21593260

Advanced real-time multi-display educational system (ARMES): An innovative real-time audiovisual mentoring tool for complex robotic surgery.

Science.gov (United States)

Lee, Joong Ho; Tanaka, Eiji; Woo, Yanghee; Ali, Güner; Son, Taeil; Kim, Hyoung-Il; Hyung, Woo Jin

2017-12-01

The recent scientific and technologic advances have profoundly affected the training of surgeons worldwide. We describe a novel intraoperative real-time training module, the Advanced Robotic Multi-display Educational System (ARMES). We created a real-time training module, which can provide a standardized step by step guidance to robotic distal subtotal gastrectomy with D2 lymphadenectomy procedures, ARMES. The short video clips of 20 key steps in the standardized procedure for robotic gastrectomy were created and integrated with TilePro™ software to delivery on da Vinci Surgical Systems (Intuitive Surgical, Sunnyvale, CA). We successfully performed the robotic distal subtotal gastrectomy with D2 lymphadenectomy for patient with gastric cancer employing this new teaching method without any transfer errors or system failures. Using this technique, the total operative time was 197 min and blood loss was 50 mL and there were no intra- or post-operative complications. Our innovative real-time mentoring module, ARMES, enables standardized, systematic guidance during surgical procedures. © 2017 Wiley Periodicals, Inc.

Soft sensor for real-time cement fineness estimation.

Science.gov (United States)

Stanišić, Darko; Jorgovanović, Nikola; Popov, Nikola; Čongradac, Velimir

2015-03-01

This paper describes the design and implementation of soft sensors to estimate cement fineness. Soft sensors are mathematical models that use available data to provide real-time information on process variables when the information, for whatever reason, is not available by direct measurement. In this application, soft sensors are used to provide information on process variable normally provided by off-line laboratory tests performed at large time intervals. Cement fineness is one of the crucial parameters that define the quality of produced cement. Providing real-time information on cement fineness using soft sensors can overcome limitations and problems that originate from a lack of information between two laboratory tests. The model inputs were selected from candidate process variables using an information theoretic approach. Models based on multi-layer perceptrons were developed, and their ability to estimate cement fineness of laboratory samples was analyzed. Models that had the best performance, and capacity to adopt changes in the cement grinding circuit were selected to implement soft sensors. Soft sensors were tested using data from a continuous cement production to demonstrate their use in real-time fineness estimation. Their performance was highly satisfactory, and the sensors proved to be capable of providing valuable information on cement grinding circuit performance. After successful off-line tests, soft sensors were implemented and installed in the control room of a cement factory. Results on the site confirm results obtained by tests conducted during soft sensor development. Copyright © 2014 ISA. Published by Elsevier Ltd. All rights reserved.

Real-time operating system timing jitter and its impact on motor control

Science.gov (United States)

Proctor, Frederick M.; Shackleford, William P.

2001-12-01

General-purpose microprocessors are increasingly being used for control applications due to their widespread availability and software support for non-control functions like networking and operator interfaces. Two classes of real-time operating systems (RTOS) exist for these systems. The traditional RTOS serves as the sole operating system, and provides all OS services. Examples include ETS, LynxOS, QNX, Windows CE and VxWorks. RTOS extensions add real-time scheduling capabilities to non-real-time OSes, and provide minimal services needed for the time-critical portions of an application. Examples include RTAI and RTL for Linux, and HyperKernel, OnTime and RTX for Windows NT. Timing jitter is an issue in these systems, due to hardware effects such as bus locking, caches and pipelines, and software effects from mutual exclusion resource locks, non-preemtible critical sections, disabled interrupts, and multiple code paths in the scheduler. Jitter is typically on the order of a microsecond to a few tens of microseconds for hard real-time operating systems, and ranges from milliseconds to seconds in the worst case for soft real-time operating systems. The question of its significance on the performance of a controller arises. Naturally, the smaller the scheduling period required for a control task, the more significant is the impact of timing jitter. Aside from this intuitive relationship is the greater significance of timing on open-loop control, such as for stepper motors, than for closed-loop control, such as for servo motors. Techniques for measuring timing jitter are discussed, and comparisons between various platforms are presented. Techniques to reduce jitter or mitigate its effects are presented. The impact of jitter on stepper motor control is analyzed.

Abstractions for aperiodic multiprocessor scheduling of real-time stream processing applications

NARCIS (Netherlands)

Hausmans, J.P.H.M.

2015-01-01

Embedded multiprocessor systems are often used in the domain of real-time stream processing applications to keep up with increasing power and performance requirements. Examples of such real-time stream processing applications are digital radio baseband processing and WLAN transceivers. These stream

Managing high-bandwidth real-time data storage

Energy Technology Data Exchange (ETDEWEB)

Bigelow, David D. [Los Alamos National Laboratory; Brandt, Scott A [Los Alamos National Laboratory; Bent, John M [Los Alamos National Laboratory; Chen, Hsing-Bung [Los Alamos National Laboratory

2009-09-23

There exist certain systems which generate real-time data at high bandwidth, but do not necessarily require the long-term retention of that data in normal conditions. In some cases, the data may not actually be useful, and in others, there may be too much data to permanently retain in long-term storage whether it is useful or not. However, certain portions of the data may be identified as being vitally important from time to time, and must therefore be retained for further analysis or permanent storage without interrupting the ongoing collection of new data. We have developed a system, Mahanaxar, intended to address this problem. It provides quality of service guarantees for incoming real-time data streams and simultaneous access to already-recorded data on a best-effort basis utilizing any spare bandwidth. It has built in mechanisms for reliability and indexing, can scale upwards to meet increasing bandwidth requirements, and handles both small and large data elements equally well. We will show that a prototype version of this system provides better performance than a flat file (traditional filesystem) based version, particularly with regard to quality of service guarantees and hard real-time requirements.

Towards Real-Time Argumentation

Directory of Open Access Journals (Sweden)

Vicente JULIÁN

2016-07-01

Full Text Available In this paper, we deal with the problem of real-time coordination with the more general approach of reaching real-time agreements in MAS. Concretely, this work proposes a real-time argumentation framework in an attempt to provide agents with the ability of engaging in argumentative dialogues and come with a solution for their underlying agreement process within a bounded period of time. The framework has been implemented and evaluated in the domain of a customer support application. Concretely, we consider a society of agents that act on behalf of a group of technicians that must solve problems in a Technology Management Centre (TMC within a bounded time. This centre controls every process implicated in the provision of technological and customer support services to private or public organisations by means of a call centre. The contract signed between the TCM and the customer establishes penalties if the specified time is exceeded.

Real-Time Scheduling for Preventing Information Leakage with Preemption Overheads

Directory of Open Access Journals (Sweden)

BAEK, H.

2017-05-01

Full Text Available Real-time systems (RTS are characterized by tasks executing in a timely manner to meet its deadlines as a real-time constraint. Most studies of RTS have focused on these criteria as primary design points. However, recent increases in security threats to various real-time systems have shown that enhanced security support must be included as an important design point, retro-fitting such support to existing systems as necessary. In this paper, we propose a new pre-flush technique referred to as flush task reservation for FP scheduling (FTR-FP to conditionally sanitize the state of resources shared by real-time tasks by invoking a flush task (FT in order to mitigate information leakage/corruption of real-time systems. FTR-FP extends existing works exploiting FTs to be applicable more general scheduling algorithms and security model. We also propose modifications to existing real-time scheduling algorithms to implement a pre-flush technique as a security constraint, and analysis technique to verify schedulability of the real-time scheduling. For better analytic capability, our analysis technique provides a count of the precise number of preemptions that a task experiences offline. Our evaluation results demonstrate that our proposed schedulability analysis improves the performance of existing scheduling algorithms in terms of schedulability and preemption cost.

Multiples least-squares reverse time migration

KAUST Repository

Zhang, Dongliang; Zhan, Ge; Dai, Wei; Schuster, Gerard T.

2013-01-01

To enhance the image quality, we propose multiples least-squares reverse time migration (MLSRTM) that transforms each hydrophone into a virtual point source with a time history equal to that of the recorded data. Since each recorded trace is treated

Optimization and Validation of a Real Time Reverse Transcriptase Polymerase Chain Reaction with RNA Internal Control to Detect Rubella RNA

Directory of Open Access Journals (Sweden)

Winny Xie

2013-12-01

Full Text Available BACKGROUND: According to a report from WHO, cases of rubella infection in Indonesia has increased up to 10-fold from 2007 to 2011. Despite no data of congenital rubella syndrome in the report, there are approximately 45,000 cases of babies born with heart failure and 0.1-0.3% live births with congenital deafness in Indonesia. Allegedly, rubella infection during pregnancy may play a role in this condition. This study aimed to optimize and validate a real-time reverse transcriptase polymerase chain reaction (RT-qPCR method to detect rubella virus RNA as an aid for the diagnosis of congenital rubella infection. METHODS: Method optimization was conducted using nucleic acids extracted from Trimovax Merieux vaccine with the High Pure Viral Nucleic Acid Kit. One step RT-qPCR was performed with Quantifast Multiplex RTPCR+R Kit. Target synthetic DNA was designed and used to determine the sensitivity of the method. RNA internal control was synthesized to control the process of extraction and amplification. RESULTS: The analytical sensitivity of this method was as low as 5 copies target synthetic DNA/μl. The mean Coefficient of Variation (CV % of the critical threshold (Ct obtained were 2.71%, 1.20%, 1.62%, and 1.59% for within run, between run, between kit lots, and between operators, respectively. Recovery of the target synthetic DNA from amniotic fluid was 100.51% (by the log copies/μl at the concentration of 1,000,000 copies/μl. CONCLUSIONS: RT-qPCR is successfully used for the detection of rubella virus RNA in vaccine and synthetic nucleic acid. With its high sensitivity, good precision and recovery, this method offers a means to improve the diagnosis of congenital rubella infection in developing countries like Indonesia. KEYWORDS: congenital rubella, RT-qPCR, prenatal diagnosis, amniotic fluid.

Time reversibility, computer simulation, algorithms, chaos

CERN Document Server

Hoover, William Graham

2012-01-01

A small army of physicists, chemists, mathematicians, and engineers has joined forces to attack a classic problem, the "reversibility paradox", with modern tools. This book describes their work from the perspective of computer simulation, emphasizing the author's approach to the problem of understanding the compatibility, and even inevitability, of the irreversible second law of thermodynamics with an underlying time-reversible mechanics. Computer simulation has made it possible to probe reversibility from a variety of directions and "chaos theory" or "nonlinear dynamics" has supplied a useful vocabulary and a set of concepts, which allow a fuller explanation of irreversibility than that available to Boltzmann or to Green, Kubo and Onsager. Clear illustration of concepts is emphasized throughout, and reinforced with a glossary of technical terms from the specialized fields which have been combined here to focus on a common theme. The book begins with a discussion, contrasting the idealized reversibility of ba...

GPU-based real-time trinocular stereo vision

Science.gov (United States)

Yao, Yuanbin; Linton, R. J.; Padir, Taskin

2013-01-01

Most stereovision applications are binocular which uses information from a 2-camera array to perform stereo matching and compute the depth image. Trinocular stereovision with a 3-camera array has been proved to provide higher accuracy in stereo matching which could benefit applications like distance finding, object recognition, and detection. This paper presents a real-time stereovision algorithm implemented on a GPGPU (General-purpose graphics processing unit) using a trinocular stereovision camera array. Algorithm employs a winner-take-all method applied to perform fusion of disparities in different directions following various image processing techniques to obtain the depth information. The goal of the algorithm is to achieve real-time processing speed with the help of a GPGPU involving the use of Open Source Computer Vision Library (OpenCV) in C++ and NVidia CUDA GPGPU Solution. The results are compared in accuracy and speed to verify the improvement.

Real-time PCR in virology.

Science.gov (United States)

Mackay, Ian M; Arden, Katherine E; Nitsche, Andreas

2002-03-15

The use of the polymerase chain reaction (PCR) in molecular diagnostics has increased to the point where it is now accepted as the gold standard for detecting nucleic acids from a number of origins and it has become an essential tool in the research laboratory. Real-time PCR has engendered wider acceptance of the PCR due to its improved rapidity, sensitivity, reproducibility and the reduced risk of carry-over contamination. There are currently five main chemistries used for the detection of PCR product during real-time PCR. These are the DNA binding fluorophores, the 5' endonuclease, adjacent linear and hairpin oligoprobes and the self-fluorescing amplicons, which are described in detail. We also discuss factors that have restricted the development of multiplex real-time PCR as well as the role of real-time PCR in quantitating nucleic acids. Both amplification hardware and the fluorogenic detection chemistries have evolved rapidly as the understanding of real-time PCR has developed and this review aims to update the scientist on the current state of the art. We describe the background, advantages and limitations of real-time PCR and we review the literature as it applies to virus detection in the routine and research laboratory in order to focus on one of the many areas in which the application of real-time PCR has provided significant methodological benefits and improved patient outcomes. However, the technology discussed has been applied to other areas of microbiology as well as studies of gene expression and genetic disease.

Real-time horizontal position control for Aditya-upgrade tokamak

International Nuclear Information System (INIS)

Kumar, Rohit; Ghosh, Joydeep; Tanna, Rakesh L.

2015-01-01

Position of plasma column is required to be controlled in real time for improved operation of any tokamak. A PID based system for real-time horizontal plasma position control has been designed for Aditya Upgrade tokamak. Modelling of transfer functions of actuators, plasma and diagnostic system are carried out for ADITYA-U tokamak. The PID controller is optimized using MATLAB-SIMULINK for horizontal position control. Further feed-forward loop is implemented where disturbance due to density variation is suppressed, which results in improved performance as compared to conventional PID operation. In this paper the detailed design of the whole system for real time control of plasma horizontal position in Aditya Upgrade tokamak is presented. (author)

Performance Analysis of FLC Controlled PV-Wind Hybrid Power System for dc Load with Real-Time Data in Matlab, Simulink

Directory of Open Access Journals (Sweden)

A. V. Pavan Kumar

2017-05-01

Full Text Available Hybrid power system is a combination of different but complementary energy generation systems based on renewable energies. The Hybrid power system harnesses most of the power from the environmental conditions, reduces the losses and repetitive maintenance, thus improving efficiency and reliability of the system. This is achieved by proper coordination control between the Renewable Energy Sources (RES. This paper focuses on the implementation of Photovoltaic - Wind hybrid power system with real-time data of environmental conditions. The continuous real-time values of the solar irradiation and wind speed are obtained from the weather monitoring system at the location. The PV will be the primary source of generation during the day and wind generation can act as power conditioning. The Hybrid model is implemented in Matlab Simulink and its performance is examined under variable environmental conditions with a variable resistive load. A scale down experiment set-up of PV-Wind hybrid system is utilized to evaluate the performance of the proposed control logic. It has emerged from the simulation and experimental study that the hybrid system implemented with the real-time data maintains the output voltage constant irrespective of environmental conditions and load condition.

A Flattened Hierarchical Scheduler for Real-Time Virtual Machines

OpenAIRE

Drescher, Michael Stuart

2015-01-01

The recent trend of migrating legacy computer systems to a virtualized, cloud-based environment has expanded to real-time systems. Unfortunately, modern hypervisors have no mechanism in place to guarantee the real-time performance of applications running on virtual machines. Past solutions to this problem rely on either spatial or temporal resource partitioning, both of which under-utilize the processing capacity of the host system. Paravirtualized solutions in which the guest communicates it...

An In-Home Digital Network Architecture for Real-Time and Non-Real-Time Communication

NARCIS (Netherlands)

Scholten, Johan; Jansen, P.G.; Hanssen, F.T.Y.; Hattink, Tjalling

2002-01-01

This paper describes an in-home digital network architecture that supports both real-time and non-real-time communication. The architecture deploys a distributed token mechanism to schedule communication streams and to offer guaranteed quality-ofservice. Essentially, the token mechanism prevents

Real-time data collection in Linux: a case study.

Science.gov (United States)

Finney, S A

2001-05-01

Multiuser UNIX-like operating systems such as Linux are often considered unsuitable for real-time data collection because of the potential for indeterminate timing latencies resulting from preemptive scheduling. In this paper, Linux is shown to be fully adequate for precisely controlled programming with millisecond resolution or better. The Linux system calls that subserve such timing control are described and tested and then utilized in a MIDI-based program for tapping and music performance experiments. The timing of this program, including data input and output, is shown to be accurate at the millisecond level. This demonstrates that Linux, with proper programming, is suitable for real-time experiment software. In addition, the detailed description and test of both the operating system facilities and the application program itself may serve as a model for publicly documenting programming methods and software performance on other operating systems.

Real-time CT-video registration for continuous endoscopic guidance

Science.gov (United States)

Merritt, Scott A.; Rai, Lav; Higgins, William E.

2006-03-01

Previous research has shown that CT-image-based guidance could be useful for the bronchoscopic assessment of lung cancer. This research drew upon the registration of bronchoscopic video images to CT-based endoluminal renderings of the airway tree. The proposed methods either were restricted to discrete single-frame registration, which took several seconds to complete, or required non-real-time buffering and processing of video sequences. We have devised a fast 2D/3D image registration method that performs single-frame CT-Video registration in under 1/15th of a second. This allows the method to be used for real-time registration at full video frame rates without significantly altering the physician's behavior. The method achieves its speed through a gradient-based optimization method that allows most of the computation to be performed off-line. During live registration, the optimization iteratively steps toward the locally optimal viewpoint at which a CT-based endoluminal view is most similar to a current bronchoscopic video frame. After an initial registration to begin the process (generally done in the trachea for bronchoscopy), subsequent registrations are performed in real-time on each incoming video frame. As each new bronchoscopic video frame becomes available, the current optimization is initialized using the previous frame's optimization result, allowing continuous guidance to proceed without manual re-initialization. Tests were performed using both synthetic and pre-recorded bronchoscopic video. The results show that the method is robust to initialization errors, that registration accuracy is high, and that continuous registration can proceed on real-time video at >15 frames per sec. with minimal user-intervention.

ISSUES IN MOBILE DISTRIBUTED REAL TIME DATABASES: PERFORMANCE AND REVIEW

OpenAIRE

VISHNU SWAROOP,; Gyanendra Kumar Gupta,; UDAI SHANKER

2011-01-01

Increase in handy and small electronic devices in computing fields; it makes the computing more popularand useful in business. Tremendous advances in wireless networks and portable computing devices have led to development of mobile computing. Support of real time database system depending upon thetiming constraints, due to availability of data distributed database, and ubiquitous computing pull the mobile database concept, which emerges them in a new form of technology as mobile distributed ...

Real-time data acquisition and feedback control using Linux Intel computers

International Nuclear Information System (INIS)

Penaflor, B.G.; Ferron, J.R.; Piglowski, D.A.; Johnson, R.D.; Walker, M.L.

2006-01-01

This paper describes the experiences of the DIII-D programming staff in adapting Linux based Intel computing hardware for use in real-time data acquisition and feedback control systems. Due to the highly dynamic and unstable nature of magnetically confined plasmas in tokamak fusion experiments, real-time data acquisition and feedback control systems are in routine use with all major tokamaks. At DIII-D, plasmas are created and sustained using a real-time application known as the digital plasma control system (PCS). During each experiment, the PCS periodically samples data from hundreds of diagnostic signals and provides these data to control algorithms implemented in software. These algorithms compute the necessary commands to send to various actuators that affect plasma performance. The PCS consists of a group of rack mounted Intel Xeon computer systems running an in-house customized version of the Linux operating system tailored specifically to meet the real-time performance needs of the plasma experiments. This paper provides a more detailed description of the real-time computing hardware and custom developed software, including recent work to utilize dual Intel Xeon equipped computers within the PCS

Embedded Electro-Optic Sensor Network for the On-Site Calibration and Real-Time Performance Monitoring of Large-Scale Phased Arrays

National Research Council Canada - National Science Library

Yang, Kyoung

2005-01-01

This final report summarizes the progress during the Phase I SBIR project entitled "Embedded Electro-Optic Sensor Network for the On-Site Calibration and Real-Time Performance Monitoring of Large-Scale Phased Arrays...

Example of an in-plant near-real-time accountancy/process control system

International Nuclear Information System (INIS)

Anon.

1981-01-01

This session describes an existing computerized in-plant near-real-time accounting and process monitoring system at the Allied-General Nuclear Services (AGNS) Barnwell Nuclear Fuel Plant (BNFP). Details of the system performance, objectives, hardware, plant instrumentation, and system functions are presented. Examples of actual programs for accounting and monitoring are described and system benefits will be discussed. The purpose of this session is to enable participants to: (1) identify the major computer hardware components of functional near-real-time accounting systems; (2) identify the types of process instrumentation necessary to perform near-real-time accounting; (3) describe the major nuclear material control and accounting functions of the AGNS computer system; and (4) assess the benefits to safeguards and plant operations of a computerized near-real-time accounting system

Satellite on-board real-time SAR processor prototype

Science.gov (United States)

Bergeron, Alain; Doucet, Michel; Harnisch, Bernd; Suess, Martin; Marchese, Linda; Bourqui, Pascal; Desnoyers, Nicholas; Legros, Mathieu; Guillot, Ludovic; Mercier, Luc; Châteauneuf, François

2017-11-01

A Compact Real-Time Optronic SAR Processor has been successfully developed and tested up to a Technology Readiness Level of 4 (TRL4), the breadboard validation in a laboratory environment. SAR, or Synthetic Aperture Radar, is an active system allowing day and night imaging independent of the cloud coverage of the planet. The SAR raw data is a set of complex data for range and azimuth, which cannot be compressed. Specifically, for planetary missions and unmanned aerial vehicle (UAV) systems with limited communication data rates this is a clear disadvantage. SAR images are typically processed electronically applying dedicated Fourier transformations. This, however, can also be performed optically in real-time. Originally the first SAR images were optically processed. The optical Fourier processor architecture provides inherent parallel computing capabilities allowing real-time SAR data processing and thus the ability for compression and strongly reduced communication bandwidth requirements for the satellite. SAR signal return data are in general complex data. Both amplitude and phase must be combined optically in the SAR processor for each range and azimuth pixel. Amplitude and phase are generated by dedicated spatial light modulators and superimposed by an optical relay set-up. The spatial light modulators display the full complex raw data information over a two-dimensional format, one for the azimuth and one for the range. Since the entire signal history is displayed at once, the processor operates in parallel yielding real-time performances, i.e. without resulting bottleneck. Processing of both azimuth and range information is performed in a single pass. This paper focuses on the onboard capabilities of the compact optical SAR processor prototype that allows in-orbit processing of SAR images. Examples of processed ENVISAT ASAR images are presented. Various SAR processor parameters such as processing capabilities, image quality (point target analysis), weight and

Data acquisition and real-time bolometer tomography using LabVIEW RT

International Nuclear Information System (INIS)

Giannone, L.; Eich, T.; Fuchs, J.C.; Ravindran, M.; Ruan, Q.; Wenzel, L.; Cerna, M.; Concezzi, S.

2011-01-01

The currently available multi-core PCI Express systems running LabVIEW RT (real-time), equipped with FPGA cards for data acquisition and real-time parallel signal processing, greatly shorten the design and implementation cycles of large-scale, real-time data acquisition and control systems. This paper details a data acquisition and real-time tomography system using LabVIEW RT for the bolometer diagnostic on the ASDEX Upgrade tokamak (Max Planck Institute for Plasma Physics, Garching, Germany). The transformation matrix for tomography is pre-computed based on the geometry of distributed radiation sources and sensors. A parallelized iterative algorithm is adapted to solve a constrained linear system for the reconstruction of the radiated power density. Real-time bolometer tomography is performed with LabVIEW RT. Using multi-core machines to execute the parallelized algorithm, a cycle time well below 1 ms is reached.

Design and Performance Evaluation of an Adaptive Resource Management Framework for Distributed Real-Time and Embedded Systems

Directory of Open Access Journals (Sweden)

Chen Yingming

2008-01-01

Full Text Available Abstract Achieving end-to-end quality of service (QoS in distributed real-time embedded (DRE systems require QoS support and enforcement from their underlying operating platforms that integrates many real-time capabilities, such as QoS-enabled network protocols, real-time operating system scheduling mechanisms and policies, and real-time middleware services. As standards-based quality of service (QoS enabled component middleware automates integration and configuration activities, it is increasingly being used as a platform for developing open DRE systems that execute in environments where operational conditions, input workload, and resource availability cannot be characterized accurately a priori. Although QoS-enabled component middleware offers many desirable features, however, it historically lacked the ability to allocate resources efficiently and enable the system to adapt to fluctuations in input workload, resource availability, and operating conditions. This paper presents three contributions to research on adaptive resource management for component-based open DRE systems. First, we describe the structure and functionality of the resource allocation and control engine (RACE, which is an open-source adaptive resource management framework built atop standards-based QoS-enabled component middleware. Second, we demonstrate and evaluate the effectiveness of RACE in the context of a representative open DRE system: NASA's magnetospheric multiscale mission system. Third, we present an empirical evaluation of RACE's scalability as the number of nodes and applications in a DRE system grows. Our results show that RACE is a scalable adaptive resource management framework and yields a predictable and high-performance system, even in the face of changing operational conditions and input workload.

Design and Performance Evaluation of an Adaptive Resource Management Framework for Distributed Real-Time and Embedded Systems

Directory of Open Access Journals (Sweden)

Chenyang Lu

2008-04-01

Full Text Available Achieving end-to-end quality of service (QoS in distributed real-time embedded (DRE systems require QoS support and enforcement from their underlying operating platforms that integrates many real-time capabilities, such as QoS-enabled network protocols, real-time operating system scheduling mechanisms and policies, and real-time middleware services. As standards-based quality of service (QoS enabled component middleware automates integration and configuration activities, it is increasingly being used as a platform for developing open DRE systems that execute in environments where operational conditions, input workload, and resource availability cannot be characterized accurately a priori. Although QoS-enabled component middleware offers many desirable features, however, it historically lacked the ability to allocate resources efficiently and enable the system to adapt to fluctuations in input workload, resource availability, and operating conditions. This paper presents three contributions to research on adaptive resource management for component-based open DRE systems. First, we describe the structure and functionality of the resource allocation and control engine (RACE, which is an open-source adaptive resource management framework built atop standards-based QoS-enabled component middleware. Second, we demonstrate and evaluate the effectiveness of RACE in the context of a representative open DRE system: NASA's magnetospheric multiscale mission system. Third, we present an empirical evaluation of RACE's scalability as the number of nodes and applications in a DRE system grows. Our results show that RACE is a scalable adaptive resource management framework and yields a predictable and high-performance system, even in the face of changing operational conditions and input workload.

Neonatal periventricular leukomalacia: real-time sonographic diagnosis with CT correlation

International Nuclear Information System (INIS)

Chow, P.P.; Horgan, J.G.; Taylor, K.J.W.

1985-01-01

The utility of real-time sonography in the diagnosis of neonatal periventricular leukomalacia (PVL) has been described only recently. Six cases are reported of PVL diagnosed by serial real-time scanning. The sonographic findings were correlated with the computed tomographic findings and the clinical history. In five of six infants in whom scanning was performed, characteristic multiseptated periventricular cavitations developed 2-3 weeks after birth or later. A transition from normal to increased periventricular echogenicity was often observed before the development of the periventricular cavitations in nonhemorrhagic PVL. The parenchymal abnormality demonstrated by sonography correlated well with an abnormal neurologic outcome. It is suggested that serial real-time scanning be performed in neonates whose history suggests the possibility of hypoxic-ischemic brain injury. Nonspecific predictors of PVL include seizures, apnea, disturbed mental status, abnormal muscle tone, and leg weakness

Scalable Real-Time Negotiation Toolkit

National Research Council Canada - National Science Library

Lesser, Victor

2004-01-01

... to implement an adaptive distributed sensor network. These activities involved the development of a distributed soft, real-time heuristic resource allocation protocol, the development of a domain-independent soft, real time agent architecture...

Implementation of SoC Based Real-Time Electromagnetic Transient Simulator

Directory of Open Access Journals (Sweden)

I. Herrera-Leandro

2017-01-01

Full Text Available Real-time electromagnetic transient simulators are important tools in the design stage of new control and protection systems for power systems. Real-time simulators are used to test and stress new devices under similar conditions that the device will deal with in a real network with the purpose of finding errors and bugs in the design. The computation of an electromagnetic transient is complex and computationally demanding, due to features such as the speed of the phenomenon, the size of the network, and the presence of time variant and nonlinear elements in the network. In this work, the development of a SoC based real-time and also offline electromagnetic transient simulator is presented. In the design, the required performance is met from two sides, (a using a technique to split the power system into smaller subsystems, which allows parallelizing the algorithm, and (b with specialized and parallel hardware designed to boost the solution flow. The results of this work have shown that for the proposed case studies, based on a balanced distribution of the node of subsystems, the proposed approach has decreased the total simulation time by up to 99 times compared with the classical approach running on a single high performance 32-bit embedded processor ARM-Cortex A9.

Real time processor for array speckle interferometry

International Nuclear Information System (INIS)

Chin, G.; Florez, J.; Borelli, R.; Fong, W.; Miko, J.; Trujillo, C.

1989-01-01

With the construction of several new large aperture telescopes and the development of large format array detectors in the near IR, the ability to obtain diffraction limited seeing via IR array speckle interferometry offers a powerful tool. We are constructing a real-time processor to acquire image frames, perform array flat-fielding, execute a 64 x 64 element 2D complex FFT, and to average the power spectrum all within the 25 msec coherence time for speckles at near IR wavelength. The processor is a compact unit controlled by a PC with real time display and data storage capability. It provides the ability to optimize observations and obtain results on the telescope rather than waiting several weeks before the data can be analyzed and viewed with off-line methods

Validation of performance of real-time kinematic PPP. A possible tool for deformation monitoring

OpenAIRE

Martín Furones, Ángel Esteban; Anquela Julián, Ana Belén; DIMAS PAGÉS, ALEJANDRO; Cos-Gayón López, Fernando José

2015-01-01

Structural failures (bridge or building collapses) and geohazards (landslides, ground subsi- dence or earthquakes) are worldwide problems that often lead to significant economic and loss of life. Monitoring the deformation of both natural phenomena and man-made struc- tures is a major key to assessing structural dynamic responses. Actually, this monitoring process is under real-time demand for developing warning and alert systems. One of the most used techniques for real-time deformation m...

Real-time gaze estimation via pupil center tracking

Directory of Open Access Journals (Sweden)

Cazzato Dario

2018-02-01

Full Text Available Automatic gaze estimation not based on commercial and expensive eye tracking hardware solutions can enable several applications in the fields of human computer interaction (HCI and human behavior analysis. It is therefore not surprising that several related techniques and methods have been investigated in recent years. However, very few camera-based systems proposed in the literature are both real-time and robust. In this work, we propose a real-time user-calibration-free gaze estimation system that does not need person-dependent calibration, can deal with illumination changes and head pose variations, and can work with a wide range of distances from the camera. Our solution is based on a 3-D appearance-based method that processes the images from a built-in laptop camera. Real-time performance is obtained by combining head pose information with geometrical eye features to train a machine learning algorithm. Our method has been validated on a data set of images of users in natural environments, and shows promising results. The possibility of a real-time implementation, combined with the good quality of gaze tracking, make this system suitable for various HCI applications.

Tests of time reversal in neutron-nucleus scattering

International Nuclear Information System (INIS)

Bowman, J.D.

1988-01-01

Experiments to test time-reversal invariance are discussed. The experiments are based on observables constructed from the momentum and spin vectors of epithermal neutrons and from the spin of an aligned or polarized target. It is shown that the proposed tests are detailed balance tests of time-reversal invariance. The status of the experiments is briefly reviewed. 14 refs., 5 figs

Evaluation of a Multiplex Real-Time Reverse Transcriptase PCR Assay for Detection and Differentiation of Influenza Viruses A and B during the 2001-2002 Influenza Season in Israel

Science.gov (United States)

Hindiyeh, Musa; Levy, Virginia; Azar, Roberto; Varsano, Noemi; Regev, Liora; Shalev, Yael; Grossman, Zehava; Mendelson, Ella

2005-01-01

The ability to rapidly diagnose influenza virus infections is of the utmost importance in the evaluation of patients with upper respiratory tract infections. It is also important for the influenza surveillance activities performed by national influenza centers. In the present study we modified a multiplex real-time reverse transcriptase PCR (RT-PCR) assay (which uses TaqMan chemistry) and evaluated it for its ability to detect and concomitantly differentiate influenza viruses A and B in 370 patient samples collected during the 2001-2002 influenza season in Israel. The performance of the TaqMan assay was compared to those of a multiplex one-step RT-PCR with gel detection, a shell vial immunofluorescence assay, and virus isolation in tissue culture. The TaqMan assay had an excellent sensitivity for the detection of influenza viruses compared to that of tissue culture. The overall sensitivity and specificity of the TaqMan assay compared to the results of culture were 98.4 and 85.5%, respectively. The sensitivity and specificity of the TaqMan assay for the detection of influenza virus A alone were 100 and 91.1%, respectively. On the other hand, the sensitivity and specificity for the detection of influenza virus B alone were 95.7 and 98.7%, respectively. The rapid turnaround time for the performance of the TaqMan assay (4.5 h) and the relatively low direct cost encourage the routine use of this assay in place of tissue culture. We conclude that the multiplex TaqMan assay is highly suitable for the rapid diagnosis of influenza virus infections both in well-established molecular biology laboratories and in reference clinical laboratories. PMID:15695650

Real-time resource allocation for tracking systems

NARCIS (Netherlands)

Satsangi, Y.; Whiteson, S.; Oliehoek, F.A.; Bouma, H.

2017-01-01

Automated tracking is key to many computer vision applications. However, many tracking systems struggle to perform in real-time due to the high computational cost of detecting people, especially in ultra high resolution images. We propose a new algorithm called PartiMax that greatly reduces this

Can Training in a Real-Time Strategy Videogame Attenuate Cognitive Decline in Older Adults?

Science.gov (United States)

Basak, Chandramallika; Boot, Walter R.; Voss, Michelle W.; Kramer, Arthur F.

2014-01-01

Declines in various cognitive abilities, particularly executive control functions, are observed in older adults. An important goal of cognitive training is to slow or reverse these age-related declines. However, opinion is divided in the literature regarding whether cognitive training can engender transfer to a variety of cognitive skills in older adults. Yet, recent research indicates that videogame training of young adults may engender broad transfer to skills of visual attention. In the current study, we used a real-time strategy videogame to attempt to train executive functions in older adults, such as working memory, task switching, short-term memory, inhibition, and reasoning. Older adults were either trained in a real-time strategy videogame for 23.5 hours (RON, n=20) or not (CONTROLS, n=20). A battery of cognitive tasks, including tasks of executive control and visuo-spatial skills, were assessed before, during, and after video game training. The trainees improved significantly in the measures of game performance. They also improved significantly more than the controls in a subset of the cognitive tasks, such as task switching, working memory, visual short term memory, and mental rotation. Trends in improvement were also observed, for the video game trainees, in inhibition and reasoning. Individual differences in changes in game performance were correlated with improvements in task-switching. The study has implications for the enhancement of executive control processes of older adults. PMID:19140648

Real-time RT-PCR, a necessary tool to support the diagnosis and surveillance of rotavirus in Mexico.

Science.gov (United States)

De La Cruz Hernández, Sergio Isaac; Anaya Molina, Yazmin; Gómez Santiago, Fabián; Terán Vega, Heidi Lizbeth; Monroy Leyva, Elda; Méndez Pérez, Héctor; García Lozano, Herlinda

2018-04-01

Rotavirus produces diarrhea in children under 5 years old. Most of those conventional methods such as polyacrylamide gel electrophoresis (PAGE) and reverse transcription-polymerase chain reaction (RT-PCR) have been used for rotavirus detection. However, these techniques need a multi-step process to get the results. In comparison with conventional methods, the real-time RT-PCR is a highly sensitive method, which allows getting the results in only one day. In this study a real-time RT-PCR assay was tested using a panel of 440 samples from patients with acute gastroenteritis, and characterized by PAGE and RT-PCR. The results show that the real-time RT-PCR detected rotavirus from 73% of rotavirus-negative samples analyzed by PAGE and RT-PCR; thus, the percentage of rotavirus-positive samples increased to 81%. The results indicate that this real-time RT-PCR should be part of a routine analysis, and as a support of the diagnosis of rotavirus in Mexico. Copyright © 2017 Elsevier Inc. All rights reserved.

Model Checking Real-Time Systems

DEFF Research Database (Denmark)

Bouyer, Patricia; Fahrenberg, Uli; Larsen, Kim Guldstrand

2018-01-01

This chapter surveys timed automata as a formalism for model checking real-time systems. We begin with introducing the model, as an extension of finite-state automata with real-valued variables for measuring time. We then present the main model-checking results in this framework, and give a hint...

Modular specification of real-time systems

DEFF Research Database (Denmark)

Inal, Recep

1994-01-01

Duration Calculus, a real-time interval logic, has been embedded in the Z specification language to provide a notation for real-time systems that combines the modularisation and abstraction facilities of Z with a logic suitable for reasoning about real-time properties. In this article the notation...

Hard Real-Time Networking on Firewire

NARCIS (Netherlands)

Zhang, Yuchen; Orlic, Bojan; Visser, Peter; Broenink, Jan

2005-01-01

This paper investigates the possibility of using standard, low-cost, widely used FireWire as a new generation fieldbus medium for real-time distributed control applications. A real-time software subsys- tem, RT-FireWire was designed that can, in combination with Linux-based real-time operating

Wide-area, real-time monitoring and visualization system

Science.gov (United States)

Budhraja, Vikram S.; Dyer, James D.; Martinez Morales, Carlos A.

2013-03-19

A real-time performance monitoring system for monitoring an electric power grid. The electric power grid has a plurality of grid portions, each grid portion corresponding to one of a plurality of control areas. The real-time performance monitoring system includes a monitor computer for monitoring at least one of reliability metrics, generation metrics, transmission metrics, suppliers metrics, grid infrastructure security metrics, and markets metrics for the electric power grid. The data for metrics being monitored by the monitor computer are stored in a data base, and a visualization of the metrics is displayed on at least one display computer having a monitor. The at least one display computer in one said control area enables an operator to monitor the grid portion corresponding to a different said control area.

Multiprocessor scheduling for real-time systems

CERN Document Server

Baruah, Sanjoy; Buttazzo, Giorgio

2015-01-01

This book provides a comprehensive overview of both theoretical and pragmatic aspects of resource-allocation and scheduling in multiprocessor and multicore hard-real-time systems.  The authors derive new, abstract models of real-time tasks that capture accurately the salient features of real application systems that are to be implemented on multiprocessor platforms, and identify rules for mapping application systems onto the most appropriate models.  New run-time multiprocessor scheduling algorithms are presented, which are demonstrably better than those currently used, both in terms of run-time efficiency and tractability of off-line analysis.  Readers will benefit from a new design and analysis framework for multiprocessor real-time systems, which will translate into a significantly enhanced ability to provide formally verified, safety-critical real-time systems at a significantly lower cost.

Evaluation of Real-time operating systems for FGC controls

CERN Document Server

Chalas, Konstantinos

2015-01-01

Power Converter Control for various experiments at CERN, is con- ducted using a machine called Function Generator Controller. The cur- rent generation of FGCs being deployed is FGC3. A certain number of FGCs require very fast and precise control, and for these systems, there is uncertainty of whether the existing hardware will be able to provide the level of determinism required. I have worked in the CCS section as a summer student on a project to study the potential of ARM-based CPUs to provide a real time behaviour fit for a future high-performance FGC4. In this paper, i will present the results of my research into real-time vari- ants of Linux and other real-time operating systems on two different ARM CPUs.

Real-Time Analytics for the Healthcare Industry: Arrhythmia Detection.

Science.gov (United States)

Agneeswaran, Vijay Srinivas; Mukherjee, Joydeb; Gupta, Ashutosh; Tonpay, Pranay; Tiwari, Jayati; Agarwal, Nitin

2013-09-01

It is time for the healthcare industry to move from the era of "analyzing our health history" to the age of "managing the future of our health." In this article, we illustrate the importance of real-time analytics across the healthcare industry by providing a generic mechanism to reengineer traditional analytics expressed in the R programming language into Storm-based real-time analytics code. This is a powerful abstraction, since most data scientists use R to write the analytics and are not clear on how to make the data work in real-time and on high-velocity data. Our paper focuses on the applications necessary to a healthcare analytics scenario, specifically focusing on the importance of electrocardiogram (ECG) monitoring. A physician can use our framework to compare ECG reports by categorization and consequently detect Arrhythmia. The framework can read the ECG signals and uses a machine learning-based categorizer that runs within a Storm environment to compare different ECG signals. The paper also presents some performance studies of the framework to illustrate the throughput and accuracy trade-off in real-time analytics.

Does real-time objective feedback and competition improve performance and quality in manikin CPR training--a prospective observational study from several European EMS.

Science.gov (United States)

Smart, J R; Kranz, K; Carmona, F; Lindner, T W; Newton, A

2015-10-15

Previous studies have reported that the quality of cardiopulmonary resuscitation (CPR) is important for patient survival. Real time objective feedback during manikin training has been shown to improve CPR performance. Objective measurement could facilitate competition and help motivate participants to improve their CPR performance. The aims of this study were to investigate whether real time objective feedback on manikins helps improve CPR performance and whether competition between separate European Emergency Medical Services (EMS) and between participants at each EMS helps motivation to train. Ten European EMS took part in the study and was carried out in two stages. At Stage 1, each EMS provided 20 pre-hospital professionals. A questionnaire was completed and standardised assessment scenarios were performed for adult and infant out of hospital cardiac arrest (OHCA). CPR performance was objectively measured and recorded but no feedback given. Between Stage 1 and 2, each EMS was given access to manikins for 6 months and instructed on how to use with objective real-time CPR feedback available. Stage 2 was undertaken and was a repeat of Stage 1 with a questionnaire with additional questions relating to usefulness of feedback and the competition nature of the study (using a 10 point Likert score). The EMS that improved the most from Stage 1 to Stage 2 was declared the winner. An independent samples Student t-test was used to analyse the objective CPR metrics with the significance level taken as p Competition between EMS organisations recorded a mean score of 5.8 and competition between participants recorded a mean score of 6.0. The results suggest that the use of real time objective feedback can significantly help improve CPR performance. Competition, especially between participants, appeared to encourage staff to practice and this study suggests that competition might have a useful role to help motivate staff to perform CPR training.

Nonlinear Time-Reversal in a Wave Chaotic System

Science.gov (United States)

Frazier, Matthew; Taddese, Biniyam; Ott, Edward; Antonsen, Thomas; Anlage, Steven

2012-02-01

Time reversal mirrors are particularly simple to implement in wave chaotic systems and form the basis for a new class of sensors [1-3]. These sensors work by applying the quantum mechanical concepts of Loschmidt echo and fidelity decay to classical waves. The sensors make explicit use of time-reversal invariance and spatial reciprocity in a wave chaotic system to remotely measure the presence of small perturbations to the system. The underlying ray chaos increases the sensitivity to small perturbations throughout the volume explored by the waves. We extend our time-reversal mirror to include a discrete element with a nonlinear dynamical response. The initially injected pulse interacts with the nonlinear element, generating new frequency components originating at the element. By selectively filtering for and applying the time-reversal mirror to the new frequency components, we focus a pulse only onto the element, without knowledge of its location. Furthermore, we demonstrate transmission of arbitrary patterns of pulses to the element, creating a targeted communication channel to the exclusion of 'eavesdroppers' at other locations in the system. [1] Appl. Phys. Lett. 95, 114103 (2009) [2] J. Appl. Phys. 108, 1 (2010) [3] Acta Physica Polonica A 112, 569 (2007)

GPU-accelerated ray-tracing for real-time treatment planning

International Nuclear Information System (INIS)

Heinrich, H; Ziegenhein, P; Kamerling, C P; Oelfke, U; Froening, H

2014-01-01

Dose calculation methods in radiotherapy treatment planning require the radiological depth information of the voxels that represent the patient volume to correct for tissue inhomogeneities. This information is acquired by time consuming ray-tracing-based calculations. For treatment planning scenarios with changing geometries and real-time constraints this is a severe bottleneck. We implemented an algorithm for the graphics processing unit (GPU) which implements a ray-matrix approach to reduce the number of rays to trace. Furthermore, we investigated the impact of different strategies of accessing memory in kernel implementations as well as strategies for rapid data transfers between main memory and memory of the graphics device. Our study included the overlapping of computations and memory transfers to reduce the overall runtime using Hyper-Q. We tested our approach on a prostate case (9 beams, coplanar). The measured execution times for a complete ray-tracing range from 28 msec for the computations on the GPU to 99 msec when considering data transfers to and from the graphics device. Our GPU-based algorithm performed the ray-tracing in real-time. The strategies efficiently reduce the time consumption of memory accesses and data transfer overhead. The achieved runtimes demonstrate the viability of this approach and allow improved real-time performance for dose calculation methods in clinical routine.

Real-time networked control of an industrial robot manipulator via discrete-time second-order sliding modes

Science.gov (United States)

Massimiliano Capisani, Luca; Facchinetti, Tullio; Ferrara, Antonella

2010-08-01

This article presents the networked control of a robotic anthropomorphic manipulator based on a second-order sliding mode technique, where the control objective is to track a desired trajectory for the manipulator. The adopted control scheme allows an easy and effective distribution of the control algorithm over two networked machines. While the predictability of real-time tasks execution is achieved by the Soft Hard Real-Time Kernel (S.Ha.R.K.) real-time operating system, the communication is established via a standard Ethernet network. The performances of the control system are evaluated under different experimental system configurations using, to perform the experiments, a COMAU SMART3-S2 industrial robot, and the results are analysed to put into evidence the robustness of the proposed approach against possible network delays, packet losses and unmodelled effects.

Performance Characteristics and Comparison of Abbott and artus Real-Time Systems for Hepatitis B Virus DNA Quantification ▿

Science.gov (United States)

Ismail, Ashrafali M.; Sivakumar, Jayashree; Anantharam, Raghavendran; Dayalan, Sujitha; Samuel, Prasanna; Fletcher, Gnanadurai J.; Gnanamony, Manu; Abraham, Priya

2011-01-01

Virological monitoring of hepatitis B virus (HBV) DNA is critical to the management of HBV infection. With several HBV DNA quantification assays available, it is important to use the most efficient testing system for virological monitoring. In this study, we evaluated the performance characteristics and comparability of three HBV DNA quantification systems: Abbott HBV real-time PCR (Abbott PCR), artus HBV real-time PCR with QIAamp DNA blood kit purification (artus-DB), and artus HBV real-time PCR with the QIAamp DSP virus kit purification (artus-DSP). The lower limits of detection of these systems were established against the WHO international standards for HBV DNA and were found to be 1.43, 82, and 9 IU/ml, respectively. The intra-assay and interassay coefficients of variation of plasma samples (1 to 6 log10 IU/ml) ranged between 0.05 to 8.34% and 0.16 to 3.48% for the Abbott PCR, 1.53 to 26.85% and 0.50 to 12.89% for artus-DB, and 0.29 to 7.42% and 0.94 to 3.01% for artus-DSP, respectively. Ninety HBV clinical samples were used for comparison of assays, and paired quantitative results showed strong correlation by linear regression analysis (artus-DB with Abbott PCR, r = 0.95; Abbott PCR with artus-DSP, r = 0.97; and artus-DSP with artus-DB, r = 0.94). Bland-Altman analysis showed a good level of agreement for Abbott PCR and artus-DSP, with a mean difference of 0.10 log10 IU/ml and limits of agreement of −0.91 to 1.11 log10 IU/ml. No genotype-specific bias was seen in all three systems for HBV genotypes A, C, and D, which are predominant in this region. This finding illustrates that the Abbott real-time HBV and artus-DSP systems show more comparable performance than the artus-DB system, meeting the current guidelines for assays to be used in the management of hepatitis B. PMID:21795507

Least squares reverse time migration of controlled order multiples

Science.gov (United States)

Liu, Y.

2016-12-01

Imaging using the reverse time migration of multiples generates inherent crosstalk artifacts due to the interference among different order multiples. Traditionally, least-square fitting has been used to address this issue by seeking the best objective function to measure the amplitude differences between the predicted and observed data. We have developed an alternative objective function by decomposing multiples into different orders to minimize the difference between Born modeling predicted multiples and specific-order multiples from observational data in order to attenuate the crosstalk. This method is denoted as the least-squares reverse time migration of controlled order multiples (LSRTM-CM). Our numerical examples demonstrated that the LSRTM-CM can significantly improve image quality compared with reverse time migration of multiples and least-square reverse time migration of multiples. Acknowledgments This research was funded by the National Nature Science Foundation of China (Grant Nos. 41430321 and 41374138).

Prototyping real-time systems

OpenAIRE

Clynch, Gary

1994-01-01

The traditional software development paradigm, the waterfall life cycle model, is defective when used for developing real-time systems. This thesis puts forward an executable prototyping approach for the development of real-time systems. A prototyping system is proposed which uses ESML (Extended Systems Modelling Language) as a prototype specification language. The prototyping system advocates the translation of non-executable ESML specifications into executable LOOPN (Language of Object ...

Real-time traffic signal optimization model based on average delay time per person

Directory of Open Access Journals (Sweden)

Pengpeng Jiao

2015-10-01

Full Text Available Real-time traffic signal control is very important for relieving urban traffic congestion. Many existing traffic control models were formulated using optimization approach, with the objective functions of minimizing vehicle delay time. To improve people’s trip efficiency, this article aims to minimize delay time per person. Based on the time-varying traffic flow data at intersections, the article first fits curves of accumulative arrival and departure vehicles, as well as the corresponding functions. Moreover, this article transfers vehicle delay time to personal delay time using average passenger load of cars and buses, employs such time as the objective function, and proposes a signal timing optimization model for intersections to achieve real-time signal parameters, including cycle length and green time. This research further implements a case study based on practical data collected at an intersection in Beijing, China. The average delay time per person and queue length are employed as evaluation indices to show the performances of the model. The results show that the proposed methodology is capable of improving traffic efficiency and is very effective for real-world applications.

Performance of a Nonlinear Real-Time Optimal Control System for HEVs/PHEVs during Car Following

Directory of Open Access Journals (Sweden)

Kaijiang Yu

2014-01-01

Full Text Available This paper presents a real-time optimal control approach for the energy management problem of hybrid electric vehicles (HEVs and plug-in hybrid electric vehicles (PHEVs with slope information during car following. The new features of this study are as follows. First, the proposed method can optimize the engine operating points and the driving profile simultaneously. Second, the proposed method gives the freedom of vehicle spacing between the preceding vehicle and the host vehicle. Third, using the HEV/PHEV property, the desired battery state of charge is designed according to the road slopes for better recuperation of free braking energy. Fourth, all of the vehicle operating modes engine charge, electric vehicle, motor assist and electric continuously variable transmission, and regenerative braking, can be realized using the proposed real-time optimal control approach. Computer simulation results are shown among the nonlinear real-time optimal control approach and the ADVISOR rule-based approach. The conclusion is that the nonlinear real-time optimal control approach is effective for the energy management problem of the HEV/PHEV system during car following.

Real-time tracking with a 3D-flow processor array

International Nuclear Information System (INIS)

Crosetto, D.

1993-01-01

The problem of real-time track-finding has been performed to date with CAM (Content Addressable Memories) or with fast coincidence logic, because the processing scheme was though to have much slower performance. Advances in technology together with a new architectural approach make it feasible to also explore the computing technique for real-time track finding thus giving the advantages of implementing algorithms that can find more parameters such as calculate the sagitta, curvature, pt, etc. with respect to the CAM approach. This report describes real-time track finding using a new computing approach technique based on the 3D-flow array processor system. This system consists of a fixed interconnection architexture scheme, allowing flexible algorithm implementation on a scalable platform. The 3D-Flow parallel processing system for track finding is scalable in size and performance by either increasing the number of processors, or increasing the speed or else the number of pipelined stages. The present article describes the conceptual idea and the design stage of the project

Real-time tracking with a 3D-Flow processor array

International Nuclear Information System (INIS)

Crosetto, D.

1993-06-01

The problem of real-time track-finding has been performed to date with CAM (Content Addressable Memories) or with fast coincidence logic, because the processing scheme was thought to have much slower performance. Advances in technology together with a new architectural approach make it feasible to also explore the computing technique for real-time track finding thus giving the advantages of implementing algorithms that can find more parameters such as calculate the sagitta, curvature, pt, etc., with respect to the CAM approach. The report describes real-time track finding using new computing approach technique based on the 3D-Flow array processor system. This system consists of a fixed interconnection architecture scheme, allowing flexible algorithm implementation on a scalable platform. The 3D-Flow parallel processing system for track finding is scalable in size and performance by either increasing the number of processors, or increasing the speed or else the number of pipelined stages. The present article describes the conceptual idea and the design stage of the project

Software Design Methods for Real-Time Systems

Science.gov (United States)

1989-12-01

This module describes the concepts and methods used in the software design of real time systems . It outlines the characteristics of real time systems , describes...the role of software design in real time system development, surveys and compares some software design methods for real - time systems , and

Real-time Pricing in Power Markets

DEFF Research Database (Denmark)

Boom, Anette; Schwenen, Sebastian

We examine welfare e ects of real-time pricing in electricity markets. Before stochastic energy demand is known, competitive retailers contract with nal consumers who exogenously do not have real-time meters. After demand is realized, two electricity generators compete in a uniform price auction...... to satisfy demand from retailers acting on behalf of subscribed customers and from consumers with real-time meters. Increasing the number of consumers on real-time pricing does not always increase welfare since risk-averse consumers dislike uncertain and high prices arising through market power...

Real-time Pricing in Power Markets

DEFF Research Database (Denmark)

Boom, Anette; Schwenen, Sebastian

We examine welfare eects of real-time pricing in electricity markets. Before stochastic energy demand is known, competitive retailers contract with nal consumers who exogenously do not have real-time meters. After demand is realized, two electricity generators compete in a uniform price auction...... to satisfy demand from retailers acting on behalf of subscribed customers and from consumers with real-time meters. Increasing the number of consumers on real-time pricing does not always increase welfare since risk-averse consumers dislike uncertain and high prices arising through market power...

Distributed, Embedded and Real-time Java Systems

CERN Document Server

Wellings, Andy

2012-01-01

Research on real-time Java technology has been prolific over the past decade, leading to a large number of corresponding hardware and software solutions, and frameworks for distributed and embedded real-time Java systems.  This book is aimed primarily at researchers in real-time embedded systems, particularly those who wish to understand the current state of the art in using Java in this domain.  Much of the work in real-time distributed, embedded and real-time Java has focused on the Real-time Specification for Java (RTSJ) as the underlying base technology, and consequently many of the Chapters in this book address issues with, or solve problems using, this framework. Describes innovative techniques in: scheduling, memory management, quality of service and communication systems supporting real-time Java applications; Includes coverage of multiprocessor embedded systems and parallel programming; Discusses state-of-the-art resource management for embedded systems, including Java’s real-time garbage collect...

A Contribution to Real-Time Experiments in Remote Laboratories

Directory of Open Access Journals (Sweden)

Zoltán Janík

2013-02-01

Full Text Available The paper is focused on realization of hard real-time control of experiments in on-line laboratories. The presented solution utilizes already developed on-line laboratory portal that is based on open-source Scilab environment. The customized solution is based on Linux RTAI platform with RTAI-XML server, Comedi and jRTAILab with support of ScicosLab environment. It generates real-time executable code that is used to operate student experiments performed on Humusoft CE152 Magnetic Levitation plant.

Real time traffic models, decision support for traffic management

NARCIS (Netherlands)

Wismans, Luc Johannes Josephus; de Romph, E.; Friso, K.; Zantema, K.

2014-01-01

Reliable and accurate short-term traffic state prediction can improve the performance of real-time traffic management systems significantly. Using this short-time prediction based on current measurements delivered by advanced surveillance systems will support decision-making processes on various

Real Time Traffic Models, Decision Support for Traffic Management

NARCIS (Netherlands)

Wismans, L.; De Romph, E.; Friso, K.; Zantema, K.

2014-01-01

Reliable and accurate short-term traffic state prediction can improve the performance of real-time traffic management systems significantly. Using this short-time prediction based on current measurements delivered by advanced surveillance systems will support decision-making processes on various

Research of real-time communication software

Science.gov (United States)

Li, Maotang; Guo, Jingbo; Liu, Yuzhong; Li, Jiahong

2003-11-01

Real-time communication has been playing an increasingly important role in our work, life and ocean monitor. With the rapid progress of computer and communication technique as well as the miniaturization of communication system, it is needed to develop the adaptable and reliable real-time communication software in the ocean monitor system. This paper involves the real-time communication software research based on the point-to-point satellite intercommunication system. The object-oriented design method is adopted, which can transmit and receive video data and audio data as well as engineering data by satellite channel. In the real-time communication software, some software modules are developed, which can realize the point-to-point satellite intercommunication in the ocean monitor system. There are three advantages for the real-time communication software. One is that the real-time communication software increases the reliability of the point-to-point satellite intercommunication system working. Second is that some optional parameters are intercalated, which greatly increases the flexibility of the system working. Third is that some hardware is substituted by the real-time communication software, which not only decrease the expense of the system and promotes the miniaturization of communication system, but also aggrandizes the agility of the system.

Real-Time Distribution Feeder Performance Monitoring, Advisory Control, and Health Management System

Energy Technology Data Exchange (ETDEWEB)

Stoupis, James; Mousavi, Mirrasoul

2014-09-30

provides this time and helps accelerate service restoration ultimately. To demonstrate the effectiveness of this feature, a demo system using substation data alone was set up to compare the minutes saved over a period of 22 months for two feeders where the real-time notification system has been deployed. The metric used for performance assessment is the time difference between the actual outage time from the OMS versus the time the notification email was received on the operators desk. Over the period of 22 months, we have accumulated over 7600 minutes (32 hours) ahead of actual outage time compared to the OMS timestamps. The significance of this analysis is that it shows the potential to reduce the SAIDI minutes and directly impact utility performance in terms of outage duration. If deployed at scale, it would have a significant impact on system reliability. To put this number in perspective, it would be helpful to assign a dollar figure to the potential savings that could be realized. According to the host utility, the average cost for each customer-minute-out (CMO) is approximately $0.30 across the operating company. This includes both direct and indirect costs such as bad press. The outage data over the previous 4 years show that the average customer count on primary/tap level outages is about 56. Accordingly, the total minutes saved amounts to 425,600 CMOs on the average. This would in turn result in a potential cost savings figure of $127,680 for two feeders alone over the period of performance. This empirical evidence validates the strong value proposition of the project that was contemplated at the onset and its potential impact to reduce outage duration in support of DOE’s goal of 20%

Real-time Astrometry Using Phase Congruency

Science.gov (United States)

Lambert, A.; Polo, M.; Tang, Y.

Phase congruency is a computer vision technique that proves to perform well for determining the tracks of optical objects (Flewelling, AMOS 2014). We report on a real-time implementation of this using an FPGA and CMOS Image Sensor, with on-sky data. The lightweight instrument can provide tracking update signals to the mount of the telescope, as well as determine abnormal objects in the scene.

Performance of the reverse Helmbold universal portfolio

Science.gov (United States)

Tan, Choon Peng; Kuang, Kee Seng; Lee, Yap Jia

2017-04-01

The universal portfolio is an important investment strategy in a stock market where no stochastic model is assumed for the stock prices. The zero-gradient set of the objective function estimating the next-day portfolio which contains the reverse Kullback-Leibler order-alpha divergence is considered. From the zero-gradient set, the explicit, reverse Helmbold universal portfolio is obtained. The performance of the explicit, reverse Helmbold universal portfolio is studied by running them on some stock-price data sets from the local stock exchange. It is possible to increase the wealth of the investor by using these portfolios in investment.

Data processing system for real-time control

International Nuclear Information System (INIS)

Oasa, K.; Mochizuki, O.; Toyokawa, R.; Yahiro, K.

1983-01-01

Real-time control, for large Tokamak JT-60, requires various data processings between diagnostic devices to control system. These processings require to high speed performance so that it aims at giving information necessary for feedback control during discharges. Then, the architecture of this system has hierachical structure of processors. These processors are connected each other by the CAMAC modules and the optical communication network, which is the 5 M bytes/second CAMAC serial highway. This system has two kinds of intelligences for this purpose. One is ACM-PU pairs in some torus hall crates which has a microcomputerized auxiliary controller and a preprocessing unit. Other is real-time processor which has a minicomputer and preprocessing unit. Most of the real-time processing, for example Abel inversion are characteristic to the diagnostic devices. Such a processing is carried out by an ACM-PU pair in the crate dedicated to the diagnostic device. Some processings, however, are also necessary which compute secondary parameters as functions of primary parameters. A typical example is Zeff, which is a function of Te, Ne and bremsstrahluny intensity. The real-time processor is equipped for such secondary processings and transfer the results. Preprocessing unit -PU- attached to ACM and real-time processor contains a signal processor, which executes in parallel such function as move, add and multiply during one micro-instruction cycle of 200 nsec. According to the progress of the experiment, more high speed processing are required, so the authors developed the PU-X module that contains multi signal processors. After a shot, inter-shot-processor which consists of general-purpose computers, gathers data into the database, then analyze them, and improve these processes to more effective

Real-time control using open source RTOS

Science.gov (United States)

Irwin, Philip C.; Johnson, Richard L., Jr.

2002-12-01

Complex telescope systems such as interferometers tend to rely heavily on hard real-time operating systems (RTOS). It has been standard practice at NASA's Jet Propulsion Laboratory (JPL) and many other institutions to use costly commercial RTOSs and hardware. After developing a real-time toolkit for VxWorks on the PowerPC platform (dubbed RTC), the interferometry group at JPL is porting this code to the real-time Application Interface (RTAI), an open source RTOS that is essentially an extension to the Linux kernel. This port has the potential to reduce software and hardware costs for future projects, while increasing the level of performance. The goals of this paper are to briefly describe the RTC toolkit, highlight the successes and pitfalls of porting the toolkit from VxWorks to Linux-RTAI, and to discuss future enhancements that will be implemented as a direct result of this port. The first port of any body of code is always the most difficult since it uncovers the OS-specific calls and forces "red flags" into those portions of the code. For this reason, It has also been a huge benefit that the project chose a generic, platform independent OS extension, ACE, and its CORBA counterpart, TAO. This port of RTC will pave the way for conversions to other environments, the most interesting of which is a non-real-time simulation environment, currently being considered by the Space Interferometry Mission (SIM) and the Terrestrial Planet Finder (TPF) Projects.

Real time capable infrared thermography for ASDEX Upgrade

Energy Technology Data Exchange (ETDEWEB)

Sieglin, B., E-mail: Bernhard.Sieglin@ipp.mpg.de; Faitsch, M.; Herrmann, A.; Brucker, B.; Eich, T.; Kammerloher, L.; Martinov, S. [Max-Planck Institute for Plasma Physics, Boltzmannstr. 2, D-85748 Garching (Germany)

2015-11-15

Infrared (IR) thermography is widely used in fusion research to study power exhaust and incident heat load onto the plasma facing components. Due to the short pulse duration of today’s fusion experiments, IR systems have mostly been designed for off-line data analysis. For future long pulse devices (e.g., Wendelstein 7-X, ITER), a real time evaluation of the target temperature and heat flux is mandatory. This paper shows the development of a real time capable IR system for ASDEX Upgrade. A compact IR camera has been designed incorporating the necessary magnetic and electric shielding for the detector, cooler assembly. The camera communication is based on the Camera Link industry standard. The data acquisition hardware is based on National Instruments hardware, consisting of a PXIe chassis inside and a fibre optical connected industry computer outside the torus hall. Image processing and data evaluation are performed using real time LabVIEW.

2-Methoxy-2,4-diphenyl-3(2H)-furanone-labeled gelatin zymography and reverse zymography: a rapid real-time method for quantification of matrix metalloproteinases-2 and -9 and tissue inhibitors of metalloproteinases.

Science.gov (United States)

Min, Danqing; Lyons, James Guy; Jia, Junhong; Lo, Lisa; McLennan, Susan V

2006-02-01

Measurement of matrix metalloproteinases (MMPs) and their specific tissue inhibitors of metalloproteinases (TIMPs) by the techniques of zymography and reverse zymography provide useful information regarding the status of matrix accumulation or breakdown. This report describes the use of 2-methoxy-2,4-diphenyl-3(2H)-furanone (MDPF), a fluorescent compound which can be used to label gelatin as a substrate for detection of the gelatin degrading MMP-2 and -9 by zymography. In addition, a modification of the zymographic technique by addition of excess MMPs enables the use of the MDPF-labeled gelatin substrate for the identification and quantification of TIMPs by reverse zymography. Both systems are real-time sensitive reliable quantification techniques, easily used for measurement of these MMPs and TIMPs in clinical, biological, and tissue culture samples.

Scene data fusion: Real-time standoff volumetric gamma-ray imaging

Energy Technology Data Exchange (ETDEWEB)

Barnowski, Ross [Department of Nuclear Engineering, UC Berkeley, 4155 Etcheverry Hall, MC 1730, Berkeley, CA 94720, United States of America (United States); Haefner, Andrew; Mihailescu, Lucian [Lawrence Berkeley National Lab - Applied Nuclear Physics, 1 Cyclotron Road, Berkeley, CA 94720, United States of America (United States); Vetter, Kai [Department of Nuclear Engineering, UC Berkeley, 4155 Etcheverry Hall, MC 1730, Berkeley, CA 94720, United States of America (United States); Lawrence Berkeley National Lab - Applied Nuclear Physics, 1 Cyclotron Road, Berkeley, CA 94720, United States of America (United States)

2015-11-11

An approach to gamma-ray imaging has been developed that enables near real-time volumetric (3D) imaging of unknown environments thus improving the utility of gamma-ray imaging for source-search and radiation mapping applications. The approach, herein dubbed scene data fusion (SDF), is based on integrating mobile radiation imagers with real-time tracking and scene reconstruction algorithms to enable a mobile mode of operation and 3D localization of gamma-ray sources. A 3D model of the scene, provided in real-time by a simultaneous localization and mapping (SLAM) algorithm, is incorporated into the image reconstruction reducing the reconstruction time and improving imaging performance. The SDF concept is demonstrated in this work with a Microsoft Kinect RGB-D sensor, a real-time SLAM solver, and a cart-based Compton imaging platform comprised of two 3D position-sensitive high purity germanium (HPGe) detectors. An iterative algorithm based on Compton kinematics is used to reconstruct the gamma-ray source distribution in all three spatial dimensions. SDF advances the real-world applicability of gamma-ray imaging for many search, mapping, and verification scenarios by improving the tractiblity of the gamma-ray image reconstruction and providing context for the 3D localization of gamma-ray sources within the environment in real-time.

Dense time discretization technique for verification of real time systems

International Nuclear Information System (INIS)

Makackas, Dalius; Miseviciene, Regina

2016-01-01

Verifying the real-time system there are two different models to control the time: discrete and dense time based models. This paper argues a novel verification technique, which calculates discrete time intervals from dense time in order to create all the system states that can be reached from the initial system state. The technique is designed for real-time systems specified by a piece-linear aggregate approach. Key words: real-time system, dense time, verification, model checking, piece-linear aggregate

Combining instruction prefetching with partial cache locking to improve WCET in real-time systems.

Directory of Open Access Journals (Sweden)

Fan Ni

Full Text Available Caches play an important role in embedded systems to bridge the performance gap between fast processor and slow memory. And prefetching mechanisms are proposed to further improve the cache performance. While in real-time systems, the application of caches complicates the Worst-Case Execution Time (WCET analysis due to its unpredictable behavior. Modern embedded processors often equip locking mechanism to improve timing predictability of the instruction cache. However, locking the whole cache may degrade the cache performance and increase the WCET of the real-time application. In this paper, we proposed an instruction-prefetching combined partial cache locking mechanism, which combines an instruction prefetching mechanism (termed as BBIP with partial cache locking to improve the WCET estimates of real-time applications. BBIP is an instruction prefetching mechanism we have already proposed to improve the worst-case cache performance and in turn the worst-case execution time. The estimations on typical real-time applications show that the partial cache locking mechanism shows remarkable WCET improvement over static analysis and full cache locking.

Combining instruction prefetching with partial cache locking to improve WCET in real-time systems.

Science.gov (United States)

Ni, Fan; Long, Xiang; Wan, Han; Gao, Xiaopeng

2013-01-01

Caches play an important role in embedded systems to bridge the performance gap between fast processor and slow memory. And prefetching mechanisms are proposed to further improve the cache performance. While in real-time systems, the application of caches complicates the Worst-Case Execution Time (WCET) analysis due to its unpredictable behavior. Modern embedded processors often equip locking mechanism to improve timing predictability of the instruction cache. However, locking the whole cache may degrade the cache performance and increase the WCET of the real-time application. In this paper, we proposed an instruction-prefetching combined partial cache locking mechanism, which combines an instruction prefetching mechanism (termed as BBIP) with partial cache locking to improve the WCET estimates of real-time applications. BBIP is an instruction prefetching mechanism we have already proposed to improve the worst-case cache performance and in turn the worst-case execution time. The estimations on typical real-time applications show that the partial cache locking mechanism shows remarkable WCET improvement over static analysis and full cache locking.

Real-Time-Simulation of IEEE-5-Bus Network on OPAL-RT-OP4510 Simulator

Science.gov (United States)

Atul Bhandakkar, Anjali; Mathew, Lini, Dr.

2018-03-01

The Real-Time Simulator tools have high computing technologies, improved performance. They are widely used for design and improvement of electrical systems. The advancement of the software tools like MATLAB/SIMULINK with its Real-Time Workshop (RTW) and Real-Time Windows Target (RTWT), real-time simulators are used extensively in many engineering fields, such as industry, education, and research institutions. OPAL-RT-OP4510 is a Real-Time Simulator which is used in both industry and academia. In this paper, the real-time simulation of IEEE-5-Bus network is carried out by means of OPAL-RT-OP4510 with CRO and other hardware. The performance of the network is observed with the introduction of fault at various locations. The waveforms of voltage, current, active and reactive power are observed in the MATLAB simulation environment and on the CRO. Also, Load Flow Analysis (LFA) of IEEE-5-Bus network is computed using MATLAB/Simulink power-gui load flow tool.

[Effects of real-time audiovisual feedback on secondary-school students' performance of chest compressions].

Science.gov (United States)

Abelairas-Gómez, Cristian; Rodríguez-Núñez, Antonio; Vilas-Pintos, Elisardo; Prieto Saborit, José Antonio; Barcala-Furelos, Roberto

2015-06-01

To describe the quality of chest compressions performed by secondary-school students trained with a realtime audiovisual feedback system. The learners were 167 students aged 12 to 15 years who had no prior experience with cardiopulmonary resuscitation (CPR). They received an hour of instruction in CPR theory and practice and then took a 2-minute test, performing hands-only CPR on a child mannequin (Prestan Professional Child Manikin). Lights built into the mannequin gave learners feedback about how many compressions they had achieved and clicking sounds told them when compressions were deep enough. All the learners were able to maintain a steady enough rhythm of compressions and reached at least 80% of the targeted compression depth. Fewer correct compressions were done in the second minute than in the first (P=.016). Real-time audiovisual feedback helps schoolchildren aged 12 to 15 years to achieve quality chest compressions on a mannequin.

Real Time Speed Measure while Automobile Braking on Soft Sensing Technique

Energy Technology Data Exchange (ETDEWEB)

Zhu, W B; Li, D S; Lu, Y [China Jiliang University, Hangzhou, Zhejiang province, 310018 (China)

2006-10-15

Because the braking performance of automobile has close relationship to traffic safety, it is important to detect that. Focusing on the problem that the real time speed is difficult to obtain in detection process, soft sensing technique is introduced in this paper. According to analyzing the relationship of the dynamics equation of a moving automobile, a module of real time speed of braking is set up. By using imitation method with experiment data to get the pressure function of cylinder and analyzing the relationship between the trigging moment of a wheel and the pressure function of brake cylinder, the real time speed is confirmed in good precision. The maximal measurement error of real time speed is 8.7% and the precision can satisfy engineering request.

Real Time Speed Measure while Automobile Braking on Soft Sensing Technique

International Nuclear Information System (INIS)

Zhu, W B; Li, D S; Lu, Y

2006-01-01

Because the braking performance of automobile has close relationship to traffic safety, it is important to detect that. Focusing on the problem that the real time speed is difficult to obtain in detection process, soft sensing technique is introduced in this paper. According to analyzing the relationship of the dynamics equation of a moving automobile, a module of real time speed of braking is set up. By using imitation method with experiment data to get the pressure function of cylinder and analyzing the relationship between the trigging moment of a wheel and the pressure function of brake cylinder, the real time speed is confirmed in good precision. The maximal measurement error of real time speed is 8.7% and the precision can satisfy engineering request

Advanced Map For Real-Time Process Control

Science.gov (United States)

Shiobara, Yasuhisa; Matsudaira, Takayuki; Sashida, Yoshio; Chikuma, Makoto

1987-10-01

MAP, a communications protocol for factory automation proposed by General Motors [1], has been accepted by users throughout the world and is rapidly becoming a user standard. In fact, it is now a LAN standard for factory automation. MAP is intended to interconnect different devices, such as computers and programmable devices, made by different manufacturers, enabling them to exchange information. It is based on the OSI intercomputer com-munications protocol standard under development by the ISO. With progress and standardization, MAP is being investigated for application to process control fields other than factory automation [2]. The transmission response time of the network system and centralized management of data exchanged with various devices for distributed control are import-ant in the case of a real-time process control with programmable controllers, computers, and instruments connected to a LAN system. MAP/EPA and MINI MAP aim at reduced overhead in protocol processing and enhanced transmission response. If applied to real-time process control, a protocol based on point-to-point and request-response transactions limits throughput and transmission response. This paper describes an advanced MAP LAN system applied to real-time process control by adding a new data transmission control that performs multicasting communication voluntarily and periodically in the priority order of data to be exchanged.

Storm real-time processing cookbook

CERN Document Server

Anderson, Quinton

2013-01-01

A Cookbook with plenty of practical recipes for different uses of Storm.If you are a Java developer with basic knowledge of real-time processing and would like to learn Storm to process unbounded streams of data in real time, then this book is for you.

Analysis and Synthesis of Communication-Intensive Heterogeneous Real-Time Systems

DEFF Research Database (Denmark)

Pop, Paul

2003-01-01

Embedded computer systems are now everywhere: from alarm clocks to PDAs, from mobile phones to cars, almost all the devices we use are controlled by embedded computer systems. An important class of embedded computer systems is that of real-time systems, which have to fulfill strict timing...... requirements. As realtime systems become more complex, they are often implemented using distributed heterogeneous architectures. The main objective of this thesis is to develop analysis and synthesis methods for communication-intensive heterogeneous hard real-time systems. The systems are heterogeneous...... is the synthesis of the communication infrastructure, which has a significant impact on the overall system performance and cost. To reduce the time-to-market of products, the design of real-time systems seldom starts from scratch. Typically, designers start from an already existing system, running certain...

Real-time exception handling—Use cases and response requirements

International Nuclear Information System (INIS)

Raupp, G.; Mertens, V.; Neu, G.; Treutterer, W.; Zasche, D.; Zehetbauer, Th.

2012-01-01

Adequate real-time event detection and exception handling for machine protection and plasma optimization are important for safe and efficient operation of fusion devices. Within the scope of a layered protection hierarchy, the exception handling goals of the real-time control system are to optimize control performance, switch to alternate investigations, terminate the discharge in a controlled way, or alarm the interlock system when control is lost. Analysis of these goals shows that they can be implemented with two methods: the modification of the reference values to respond to degradation of sensors, actuators or controllers, and the replacement of schedules to perform other investigations, which includes controlled termination and interlock alarm cases. In support of these methods the sensor and evaluated data quality and the time-varying actuator characteristics and capacity must be communicated to users of those information to avoid failure propagation.

Time reversal and parity tests

International Nuclear Information System (INIS)

Terwilliger, K.

1975-01-01

A recent review by Henley discusses the present status of Time Reversal and Parity symmetry violations, and comments on the implications for high energy hadron scattering. This note will briefly summarize the situation with particular attention to the sizes of possible effects, relating them to experimental accuracy available or reasonably possible at the ZGS

Time-reversal and Bayesian inversion

Science.gov (United States)

Debski, Wojciech

2017-04-01

Probabilistic inversion technique is superior to the classical optimization-based approach in all but one aspects. It requires quite exhaustive computations which prohibit its use in huge size inverse problems like global seismic tomography or waveform inversion to name a few. The advantages of the approach are, however, so appealing that there is an ongoing continuous afford to make the large inverse task as mentioned above manageable with the probabilistic inverse approach. One of the perspective possibility to achieve this goal relays on exploring the internal symmetry of the seismological modeling problems in hand - a time reversal and reciprocity invariance. This two basic properties of the elastic wave equation when incorporating into the probabilistic inversion schemata open a new horizons for Bayesian inversion. In this presentation we discuss the time reversal symmetry property, its mathematical aspects and propose how to combine it with the probabilistic inverse theory into a compact, fast inversion algorithm. We illustrate the proposed idea with the newly developed location algorithm TRMLOC and discuss its efficiency when applied to mining induced seismic data.

Time reversal invariance for a nonlinear scatterer exhibiting contact acoustic nonlinearity

Science.gov (United States)

Blanloeuil, Philippe; Rose, L. R. Francis; Veidt, Martin; Wang, Chun H.

2018-03-01

The time reversal invariance of an ultrasonic plane wave interacting with a contact interface characterized by a unilateral contact law is investigated analytically and numerically. It is shown analytically that despite the contact nonlinearity, the re-emission of a time reversed version of the reflected and transmitted waves can perfectly recover the original pulse shape, thereby demonstrating time reversal invariance for this type of contact acoustic nonlinearity. With the aid of finite element modelling, the time-reversal analysis is extended to finite-size nonlinear scatterers such as closed cracks. The results show that time reversal invariance holds provided that all the additional frequencies generated during the forward propagation, such as higher harmonics, sub-harmonics and zero-frequency component, are fully included in the retro-propagation. If the scattered waves are frequency filtered during receiving or transmitting, such as through the use of narrowband transducers, the recombination of the time-reversed waves will not exactly recover the original incident wave. This discrepancy due to incomplete time invariance can be exploited as a new method for characterizing damage by defining damage indices that quantify the departure from time reversal invariance. The sensitivity of these damage indices for various crack lengths and contact stress levels is investigated computationally, indicating some advantages of this narrowband approach relative to the more conventional measurement of higher harmonic amplitude, which requires broadband transducers.

The evolution of real-time control systems at JET

Energy Technology Data Exchange (ETDEWEB)

Goodyear, A.; Dorling, S.; Felton, R

2001-07-01

Real-time feedback control of the JET experiment is based upon a collection of diagnostics providing signals which are processed by various controllers that manipulate actuator parameters for plasma current, shape and heating. The real-time data network (RTDN) connects the diagnostic, controller and actuator systems to form a flexible feedback and protection system for plasma monitoring and control. The controllers are mainly VME systems based on the Motorola 680X0 (68K) processor with some computationally intensive systems utilising Texas Instruments TMS320C40 (C40) digital signal processors (DSP), though lately there has been a move towards PowerPC 750 based processors. The majority of 68K VME systems use VxWorks, a hard real time operating system. There is an ongoing requirement to improve the efficiency of the real-time control systems at JET. This is driven by a desire to either add more input signals, reduce the feedback cycle time or increase algorithm complexity. New technology has a major role to play in the upgrade of the real-time control systems but the novel redeployment of existing equipment can also be used to enhance performance. This paper examines the configuration of existing systems, both hardware and software, and how new technology can be gradually integrated without jeopardising the current functionality. The adoption of Asynchronous Transfer Mode (ATM) as the connection medium for the RTDN is key to the evolutional development of the control systems. The ATM network is extremely flexible to configure and benefits from low message latency and deterministic delivery time, essential properties for a real-time network. (author)

A Real-Time Systems Symposium Preprint.

Science.gov (United States)

1983-09-01

Real - Time Systems Symposium Preprint Interim Tech...estimate of the occurence of the error. Unclassii ledSECUqITY CLASSIF’ICA T" NO MI*IA If’ inDI /’rrd erter for~~ble. ’Corrputnqg A REAL - TIME SYSTEMS SYMPOSIUM...ABSTRACT This technical report contains a preprint of a paper accepted for presentation at the REAL - TIME SYSTEMS SYMPOSIUM, Arlington,

Benefits of real-time gas management

International Nuclear Information System (INIS)

Nolty, R.; Dolezalek, D. Jr.

1994-01-01

In today's competitive gas gathering, processing, storage and transportation business environment, the requirements to do business are continually changing. These changes arise from government regulations such as the amendments to the Clean Air Act concerning the environment and FERC Order 636 concerning business practices. Other changes are due to advances in technology such as electronic flow measurement (EFM) and real-time communications capabilities within the gas industry. Gas gathering, processing, storage and transportation companies must be flexible in adapting to these changes to remain competitive. These dynamic requirements can be met with an open, real-time gas management computer information system. Such a system provides flexible services with a variety of software applications. Allocations, nominations management and gas dispatching are examples of applications that are provided on a real-time basis. By providing real-time services, the gas management system enables operations personnel to make timely adjustments within the current accounting period. Benefits realized from implementing a real-time gas management system include reduced unaccountable gas, reduced imbalance penalties, reduced regulatory violations, improved facility operations and better service to customers. These benefits give a company the competitive edge. This article discusses the applications provided, the benefits from implementing a real-time gas management system, and the definition of such a system

Benchmarking hardware architecture candidates for the NFIRAOS real-time controller

Science.gov (United States)

Smith, Malcolm; Kerley, Dan; Herriot, Glen; Véran, Jean-Pierre

2014-07-01

As a part of the trade study for the Narrow Field Infrared Adaptive Optics System, the adaptive optics system for the Thirty Meter Telescope, we investigated the feasibility of performing real-time control computation using a Linux operating system and Intel Xeon E5 CPUs. We also investigated a Xeon Phi based architecture which allows higher levels of parallelism. This paper summarizes both the CPU based real-time controller architecture and the Xeon Phi based RTC. The Intel Xeon E5 CPU solution meets the requirements and performs the computation for one AO cycle in an average of 767 microseconds. The Xeon Phi solution did not meet the 1200 microsecond time requirement and also suffered from unpredictable execution times. More detailed benchmark results are reported for both architectures.

Real-time PCR (qPCR) primer design using free online software.

Science.gov (United States)

Thornton, Brenda; Basu, Chhandak

2011-01-01

Real-time PCR (quantitative PCR or qPCR) has become the preferred method for validating results obtained from assays which measure gene expression profiles. The process uses reverse transcription polymerase chain reaction (RT-PCR), coupled with fluorescent chemistry, to measure variations in transcriptome levels between samples. The four most commonly used fluorescent chemistries are SYBR® Green dyes and TaqMan®, Molecular Beacon or Scorpion probes. SYBR® Green is very simple to use and cost efficient. As SYBR® Green dye binds to any double-stranded DNA product, its success depends greatly on proper primer design. Many types of online primer design software are available, which can be used free of charge to design desirable SYBR® Green-based qPCR primers. This laboratory exercise is intended for those who have a fundamental background in PCR. It addresses the basic fluorescent chemistries of real-time PCR, the basic rules and pitfalls of primer design, and provides a step-by-step protocol for designing SYBR® Green-based primers with free, online software. Copyright © 2010 Wiley Periodicals, Inc.

The Two-Time Interpretation and Macroscopic Time-Reversibility

Directory of Open Access Journals (Sweden)

Yakir Aharonov

2017-03-01

Full Text Available The two-state vector formalism motivates a time-symmetric interpretation of quantum mechanics that entails a resolution of the measurement problem. We revisit a post-selection-assisted collapse model previously suggested by us, claiming that unlike the thermodynamic arrow of time, it can lead to reversible dynamics at the macroscopic level. In addition, the proposed scheme enables us to characterize the classical-quantum boundary. We discuss the limitations of this approach and its broad implications for other areas of physics.

Making real-time reactive systems reliable

Science.gov (United States)

Marzullo, Keith; Wood, Mark

1990-01-01

A reactive system is characterized by a control program that interacts with an environment (or controlled program). The control program monitors the environment and reacts to significant events by sending commands to the environment. This structure is quite general. Not only are most embedded real time systems reactive systems, but so are monitoring and debugging systems and distributed application management systems. Since reactive systems are usually long running and may control physical equipment, fault tolerance is vital. The research tries to understand the principal issues of fault tolerance in real time reactive systems and to build tools that allow a programmer to design reliable, real time reactive systems. In order to make real time reactive systems reliable, several issues must be addressed: (1) How can a control program be built to tolerate failures of sensors and actuators. To achieve this, a methodology was developed for transforming a control program that references physical value into one that tolerates sensors that can fail and can return inaccurate values; (2) How can the real time reactive system be built to tolerate failures of the control program. Towards this goal, whether the techniques presented can be extended to real time reactive systems is investigated; and (3) How can the environment be specified in a way that is useful for writing a control program. Towards this goal, whether a system with real time constraints can be expressed as an equivalent system without such constraints is also investigated.

Development of sustainable performance indicators to assess the benefits of real-time monitoring in mechanised underground mining

OpenAIRE

Govindan, Rajesh; Cao, Wenzhuo; Korre, Anna; Durucan, Sevket; Graham, Peter; Simon, Clara; Barlow, Glenn; Pemberton, Ross

2018-01-01

This paper presents the development and quantification of a catalogue of Sustainable Performance Indicators (SPIs) for the assessment of the benefits real-time mining can offer in small and complex mechanised underground mining operations. The SPIs investigated in detail include: ‒ grade accuracy and error of the resource model, ‒ high/low grade ore classification accuracy and error, ‒ additional high grade ore identified per unit volume, ‒ profit expected per unit volume, ‒ or...

Fuzzy logic based power-efficient real-time multi-core system

CERN Document Server

Ahmed, Jameel; Najam, Shaheryar; Najam, Zohaib

2017-01-01

This book focuses on identifying the performance challenges involved in computer architectures, optimal configuration settings and analysing their impact on the performance of multi-core architectures. Proposing a power and throughput-aware fuzzy-logic-based reconfiguration for Multi-Processor Systems on Chip (MPSoCs) in both simulation and real-time environments, it is divided into two major parts. The first part deals with the simulation-based power and throughput-aware fuzzy logic reconfiguration for multi-core architectures, presenting the results of a detailed analysis on the factors impacting the power consumption and performance of MPSoCs. In turn, the second part highlights the real-time implementation of fuzzy-logic-based power-efficient reconfigurable multi-core architectures for Intel and Leone3 processors. .

Real-time and accelerated outdoor endurance testing of solar cells

Science.gov (United States)

Forestieri, A. F.; Anagnostou, E.

1977-01-01

Real-time and accelerated outdoor endurance testing was performed on a variety of samples of interest to the National Photovoltaic Conversion Program. The real-time tests were performed at seven different sites and the accelerated tests were performed at one of those sites in the southwestern United States. The purpose of the tests were to help evaluate the lifetime of photovoltaic systems. Three types of samples were tested; transmission samples of possible cover materials, sub-modules constructed using these materials attached to solar cells, and solar cell modules produced by the manufacturers for the ERDA program. Results indicate that suitable cover materials are glass, FEP-A and PFA. Dirt accumulation and cleanability are important factors in the selection of solar cell module covers and encapsulants.

A time reversal damage imaging method for structure health monitoring using Lamb waves

International Nuclear Information System (INIS)

Zhang Hai-Yan; Cao Ya-Ping; Sun Xiu-Li; Chen Xian-Hua; Yu Jian-Bo

2010-01-01

This paper investigates the Lamb wave imaging method combining time reversal for health monitoring of a metallic plate structure. The temporal focusing effect of the time reversal Lamb waves is investigated theoretically. It demonstrates that the focusing effect is related to the frequency dependency of the time reversal operation. Numerical simulations are conducted to study the time reversal behaviour of Lamb wave modes under broadband and narrowband excitations. The results show that the reconstructed time reversed wave exhibits close similarity to the reversed narrowband tone burst signal validating the theoretical model. To enhance the similarity, the cycle number of the excited signal should be increased. Experiments combining finite element model are then conducted to study the imaging method in the presence of damage like hole in the plate structure. In this work, the time reversal technique is used for the recompression of Lamb wave signals. Damage imaging results with time reversal using broadband and narrowband excitations are compared to those without time reversal. It suggests that the narrowband excitation combined time reversal can locate and determine the size of structural damage more precisely, but the cycle number of the excited signal should be chosen reasonably

Securing Real-Time Sessions in an IMS-Based Architecture

Science.gov (United States)

Cennamo, Paolo; Fresa, Antonio; Longo, Maurizio; Postiglione, Fabio; Robustelli, Anton Luca; Toro, Francesco

The emerging all-IP mobile network infrastructures based on 3rd Generation IP Multimedia Subsystem philosophy are characterised by radio access technology independence and ubiquitous connectivity for mobile users. Currently, great focus is being devoted to security issues since most of the security threats presently affecting the public Internet domain, and the upcoming ones as well, are going to be suffered by mobile users in the years to come. While a great deal of research activity, together with standardisation efforts and experimentations, is carried out on mechanisms for signalling protection, very few integrated frameworks for real-time multimedia data protection have been proposed in a context of IP Multimedia Subsystem, and even fewer experimental results based on testbeds are available. In this paper, after a general overview of the security issues arising in an advanced IP Multimedia Subsystem scenario, a comprehensive infrastructure for real-time multimedia data protection, based on the adoption of the Secure Real-Time Protocol, is proposed; then, the development of a testbed incorporating such functionalities, including mechanisms for key management and cryptographic context transfer, and allowing the setup of Secure Real-Time Protocol sessions is presented; finally, experimental results are provided together with quantitative assessments and comparisons of system performances for audio sessions with and without the adoption of the Secure Real-Time Protocol framework.

Space Weather and Real-Time Monitoring

Directory of Open Access Journals (Sweden)

S Watari

2009-04-01

Full Text Available Recent advance of information and communications technology enables to collect a large amount of ground-based and space-based observation data in real-time. The real-time data realize nowcast of space weather. This paper reports a history of space weather by the International Space Environment Service (ISES in association with the International Geophysical Year (IGY and importance of real-time monitoring in space weather.

Research Directions in Real-Time Systems.

Science.gov (United States)

1996-09-01

This report summarizes a survey of published research in real time systems . Material is presented that provides an overview of the topic, focusing on...communications protocols and scheduling techniques. It is noted that real - time systems deserve special attention separate from other areas because of...formal tools for design and analysis of real - time systems . The early work on applications as well as notable theoretical advances are summarized

Universal SaaS platform of internet of things for real-time monitoring

Science.gov (United States)

Liu, Tongke; Wu, Gang

2018-04-01

Real-time monitoring service, as a member of the IoT (Internet of Things) service, has a wide range application scenario. To support rapid construction and deployment of applications and avoid repetitive development works in these processes, this paper designs and develops a universal SaaS platform of IoT for real-time monitoring. Evaluation shows that this platform can provide SaaS service to multiple tenants and achieve high real-time performance under the situation of large amount of device access.

Friction coefficient of skin in real-time.

Science.gov (United States)

Sivamani, Raja K; Goodman, Jack; Gitis, Norm V; Maibach, Howard I

2003-08-01

Friction studies are useful in quantitatively investigating the skin surface. Previous studies utilized different apparatuses and materials for these investigations but there was no real-time test parameter control or monitoring. Our studies incorporated the commercially available UMT Series Micro-Tribometer, a tribology instrument that permits real-time monitoring and calculation of the important parameters in friction studies, increasing the accuracy over previous tribology and friction measurement devices used on skin. Our friction tests were performed on four healthy volunteers and on abdominal skin samples. A stainless steel ball was pressed on to the skin with at a pre-set load and then moved across the skin at a constant velocity of 5 mm/min. The UMT continuously monitored the friction force of the skin and the normal force of the ball to calculate the friction coefficient in real-time. Tests investigated the applicability of Amonton's law, the impact of increased and decreased hydration, and the effect of the application of moisturizers. The friction coefficient depends on the normal load applied, and Amonton's law does not provide an accurate description for the skin surface. Application of water to the skin increased the friction coefficient and application of isopropyl alcohol decreased it. Fast acting moisturizers immediately increased the friction coefficient, but did not have the prolonged effect of the slow, long lasting moisturizers. The UMT is capable of making real-time measurements on the skin and can be used as an effective tool to study friction properties. Results from the UMT measurements agree closely with theory regarding the skin surface.

In vivo Real-Time Mass Spectrometry for Guided Surgery Application

Science.gov (United States)

Fatou, Benoit; Saudemont, Philippe; Leblanc, Eric; Vinatier, Denis; Mesdag, Violette; Wisztorski, Maxence; Focsa, Cristian; Salzet, Michel; Ziskind, Michael; Fournier, Isabelle

2016-05-01

Here we describe a new instrument (SpiderMass) designed for in vivo and real-time analysis. In this instrument ion production is performed remotely from the MS instrument and the generated ions are transported in real-time to the MS analyzer. Ion production is promoted by Resonant Infrared Laser Ablation (RIR-LA) based on the highly effective excitation of O-H bonds in water molecules naturally present in most biological samples. The retrieved molecular patterns are specific to the cell phenotypes and benign versus cancer regions of patient biopsies can be easily differentiated. We also demonstrate by analysis of human skin that SpiderMass can be used under in vivo conditions with minimal damage and pain. Furthermore SpiderMass can also be used for real-time drug metabolism and pharmacokinetic (DMPK) analysis or food safety topics. SpiderMass is thus the first MS based system designed for in vivo real-time analysis under minimally invasive conditions.

A novel photoinduced electron transfer (PET) primer technique for rapid real-time PCR detection of Cryptosporidium spp

Energy Technology Data Exchange (ETDEWEB)

Jothikumar, N., E-mail: jin2@cdc.gov; Hill, Vincent R.

2013-06-28

Highlights: •Uses a single-labeled fluorescent primer for real-time PCR. •The detection sensitivity of PET PCR was comparable to TaqMan PCR. •Melt curve analysis can be performed to confirm target amplicon production. •Conventional PCR primers can be converted to PET PCR primers. -- Abstract: We report the development of a fluorescently labeled oligonucleotide primer that can be used to monitor real-time PCR. The primer has two parts, the 3′-end of the primer is complimentary to the target and a universal 17-mer stem loop at the 5′-end forms a hairpin structure. A fluorescent dye is attached to 5′-end of either the forward or reverse primer. The presence of guanosine residues at the first and second position of the 3′ dangling end effectively quenches the fluorescence due to the photo electron transfer (PET) mechanism. During the synthesis of nucleic acid, the hairpin structure is linearized and the fluorescence of the incorporated primer increases several-fold due to release of the fluorescently labeled tail and the absence of guanosine quenching. As amplicons are synthesized during nucleic acid amplification, the fluorescence increase in the reaction mixture can be measured with commercially available real-time PCR instruments. In addition, a melting procedure can be performed to denature the double-stranded amplicons, thereby generating fluorescence peaks that can differentiate primer dimers and other non-specific amplicons if formed during the reaction. We demonstrated the application of PET-PCR for the rapid detection and quantification of Cryptosporidium parvum DNA. Comparison with a previously published TaqMan® assay demonstrated that the two real-time PCR assays exhibited similar sensitivity for a dynamic range of detection of 6000–0.6 oocysts per reaction. PET PCR primers are simple to design and less-expensive than dual-labeled probe PCR methods, and should be of interest for use by laboratories operating in resource

A novel photoinduced electron transfer (PET) primer technique for rapid real-time PCR detection of Cryptosporidium spp

International Nuclear Information System (INIS)

Jothikumar, N.; Hill, Vincent R.

2013-01-01

Highlights: •Uses a single-labeled fluorescent primer for real-time PCR. •The detection sensitivity of PET PCR was comparable to TaqMan PCR. •Melt curve analysis can be performed to confirm target amplicon production. •Conventional PCR primers can be converted to PET PCR primers. -- Abstract: We report the development of a fluorescently labeled oligonucleotide primer that can be used to monitor real-time PCR. The primer has two parts, the 3′-end of the primer is complimentary to the target and a universal 17-mer stem loop at the 5′-end forms a hairpin structure. A fluorescent dye is attached to 5′-end of either the forward or reverse primer. The presence of guanosine residues at the first and second position of the 3′ dangling end effectively quenches the fluorescence due to the photo electron transfer (PET) mechanism. During the synthesis of nucleic acid, the hairpin structure is linearized and the fluorescence of the incorporated primer increases several-fold due to release of the fluorescently labeled tail and the absence of guanosine quenching. As amplicons are synthesized during nucleic acid amplification, the fluorescence increase in the reaction mixture can be measured with commercially available real-time PCR instruments. In addition, a melting procedure can be performed to denature the double-stranded amplicons, thereby generating fluorescence peaks that can differentiate primer dimers and other non-specific amplicons if formed during the reaction. We demonstrated the application of PET-PCR for the rapid detection and quantification of Cryptosporidium parvum DNA. Comparison with a previously published TaqMan® assay demonstrated that the two real-time PCR assays exhibited similar sensitivity for a dynamic range of detection of 6000–0.6 oocysts per reaction. PET PCR primers are simple to design and less-expensive than dual-labeled probe PCR methods, and should be of interest for use by laboratories operating in resource

Toward real-time regional earthquake simulation II: Real-time Online earthquake Simulation (ROS) of Taiwan earthquakes

Science.gov (United States)

Lee, Shiann-Jong; Liu, Qinya; Tromp, Jeroen; Komatitsch, Dimitri; Liang, Wen-Tzong; Huang, Bor-Shouh

2014-06-01

We developed a Real-time Online earthquake Simulation system (ROS) to simulate regional earthquakes in Taiwan. The ROS uses a centroid moment tensor solution of seismic events from a Real-time Moment Tensor monitoring system (RMT), which provides all the point source parameters including the event origin time, hypocentral location, moment magnitude and focal mechanism within 2 min after the occurrence of an earthquake. Then, all of the source parameters are automatically forwarded to the ROS to perform an earthquake simulation, which is based on a spectral-element method (SEM). A new island-wide, high resolution SEM mesh model is developed for the whole Taiwan in this study. We have improved SEM mesh quality by introducing a thin high-resolution mesh layer near the surface to accommodate steep and rapidly varying topography. The mesh for the shallow sedimentary basin is adjusted to reflect its complex geometry and sharp lateral velocity contrasts. The grid resolution at the surface is about 545 m, which is sufficient to resolve topography and tomography data for simulations accurate up to 1.0 Hz. The ROS is also an infrastructural service, making online earthquake simulation feasible. Users can conduct their own earthquake simulation by providing a set of source parameters through the ROS webpage. For visualization, a ShakeMovie and ShakeMap are produced during the simulation. The time needed for one event is roughly 3 min for a 70 s ground motion simulation. The ROS is operated online at the Institute of Earth Sciences, Academia Sinica (http://ros.earth.sinica.edu.tw/). Our long-term goal for the ROS system is to contribute to public earth science outreach and to realize seismic ground motion prediction in real-time.

A novel method of multiple nucleic acid detection: Real-time RT-PCR coupled with probe-melting curve analysis.