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Sample records for performed homozygosity mapping

  1. Homozygosity mapping in autosomal recessive retinitis pigmentosa families detects novel mutations

    Science.gov (United States)

    Marzouka, Nour al Dain; Hebrard, Maxime; Manes, Gaël; Sénéchal, Audrey; Meunier, Isabelle; Hamel, Christian P.

    2013-01-01

    Purpose Autosomal recessive retinitis pigmentosa (arRP) is a genetically heterogeneous disease resulting in progressive loss of photoreceptors that leads to blindness. To date, 36 genes are known to cause arRP, rendering the molecular diagnosis a challenge. The aim of this study was to use homozygosity mapping to identify the causative mutation in a series of inbred families with arRP. Methods arRP patients underwent standard ophthalmic examination, Goldman perimetry, fundus examination, retinal OCT, autofluorescence measurement, and full-field electroretinogram. Fifteen consanguineous families with arRP excluded for USH2A and EYS were genotyped on 250 K SNP arrays. Homozygous regions were listed, and known genes within these regions were PCR sequenced. Familial segregation and mutation analyzes were performed. Results We found ten mutations, seven of which were novel mutations in eight known genes, including RP1, IMPG2, NR2E3, PDE6A, PDE6B, RLBP1, CNGB1, and C2ORF71, in ten out of 15 families. The patients carrying RP1, C2ORF71, and IMPG2 mutations presented with severe RP, while those with PDE6A, PDE6B, and CNGB1 mutations were less severely affected. The five families without mutations in known genes could be a source of identification of novel genes. Conclusions Homozygosity mapping combined with systematic screening of known genes results in a positive molecular diagnosis in 66.7% of families. PMID:24339724

  2. Homozygosity mapping and targeted sanger sequencing reveal genetic defects underlying inherited retinal disease in families from pakistan.

    Directory of Open Access Journals (Sweden)

    Maleeha Maria

    Full Text Available Homozygosity mapping has facilitated the identification of the genetic causes underlying inherited diseases, particularly in consanguineous families with multiple affected individuals. This knowledge has also resulted in a mutation dataset that can be used in a cost and time effective manner to screen frequent population-specific genetic variations associated with diseases such as inherited retinal disease (IRD.We genetically screened 13 families from a cohort of 81 Pakistani IRD families diagnosed with Leber congenital amaurosis (LCA, retinitis pigmentosa (RP, congenital stationary night blindness (CSNB, or cone dystrophy (CD. We employed genome-wide single nucleotide polymorphism (SNP array analysis to identify homozygous regions shared by affected individuals and performed Sanger sequencing of IRD-associated genes located in the sizeable homozygous regions. In addition, based on population specific mutation data we performed targeted Sanger sequencing (TSS of frequent variants in AIPL1, CEP290, CRB1, GUCY2D, LCA5, RPGRIP1 and TULP1, in probands from 28 LCA families.Homozygosity mapping and Sanger sequencing of IRD-associated genes revealed the underlying mutations in 10 families. TSS revealed causative variants in three families. In these 13 families four novel mutations were identified in CNGA1, CNGB1, GUCY2D, and RPGRIP1.Homozygosity mapping and TSS revealed the underlying genetic cause in 13 IRD families, which is useful for genetic counseling as well as therapeutic interventions that are likely to become available in the near future.

  3. Molecular diagnosis of known recessive ataxias by homozygosity mapping with SNP arrays.

    Science.gov (United States)

    H'mida-Ben Brahim, D; M'zahem, A; Assoum, M; Bouhlal, Y; Fattori, F; Anheim, M; Ali-Pacha, L; Ferrat, F; Chaouch, M; Lagier-Tourenne, C; Drouot, N; Thibaut, C; Benhassine, T; Sifi, Y; Stoppa-Lyonnet, D; N'Guyen, K; Poujet, J; Hamri, A; Hentati, F; Amouri, R; Santorelli, F M; Tazir, M; Koenig, M

    2011-01-01

    The diagnosis of rare inherited diseases is becoming more and more complex as an increasing number of clinical conditions appear to be genetically heterogeneous. Multigenic inheritance also applies to the autosomal recessive progressive cerebellar ataxias (ARCAs), for which 14 genes have been identified and more are expected to be discovered. We used homozygosity mapping as a guide for identification of the defective locus in patients with ARCA born from consanguineous parents. Patients from 97 families were analyzed with GeneChip Mapping 10K or 50K SNP Affymetrix microarrays. We identified six families homozygous for regions containing the autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) gene, two families homozygous for the ataxia-telangiectasia gene (ATM), two families homozygous for the ataxia with oculomotor apraxia type 1 (AOA1) gene, and one family homozygous for the AOA type 2 (AOA2) gene. Upon direct gene testing, we were able to identify a disease-related mutation in all families but one of the two kindred homozygous at the ATM locus. Although linkage analyses pointed to a single locus on chromosome 11q22.1-q23.1 for this family, clinical features, normal levels of serum alpha-foetoprotein as well as absence of mutations in the ATM gene rather suggest the existence of an additional ARCA-related gene in that interval. While the use of homozygosity mapping was very effective at pointing to the correct gene, it also suggests that the majority of patients harbor mutations either in the genes of the rare forms of ARCA or in genes yet to be identified.

  4. Homozygosity mapping in albinism patients using a novel panel of 13 STR markers inside the nonsyndromic OCA genes: introducing 5 novel mutations.

    Science.gov (United States)

    Khordadpoor-Deilamani, Faravareh; Akbari, Mohammad Taghi; Karimipoor, Morteza; Javadi, Gholam Reza

    2016-05-01

    Albinism is a heterogeneous genetic disorder of melanin synthesis that results in hypopigmented hair, skin and eyes. It is associated with decreased visual acuity, nystagmus, strabismus and photophobia. Six genes are known to be involved in nonsyndromic oculocutaneous albinism (OCA). In this study, we aimed to find the disease causing mutations in albinism patients using homozygosity mapping. Twenty three unrelated patients with nonsyndromic OCA or autosomal recessive ocular albinism were recruited in this study. All of the patients' parents had consanguineous marriage and all were screened for TYR mutations previously. At first, we performed homozygosity mapping using fluorescently labeled primers to amplify a novel panel of 13 STR markers inside the OCA genes and then the screened loci in each family were studied using PCR and cycle sequencing methods. We found five mutations including three mutations in OCA2, one mutation in SLC45A2 and one mutation in C10ORF11 genes, all of which were novel. In cases where the disease causing mutations are identical by descent due to a common ancestor, these STR markers can enable us to screen for the responsible genes.

  5. APOA5 Q97X Mutation Identified through homozygosity mapping causes severe hypertriglyceridemia in a Chilean consanguineous family

    Directory of Open Access Journals (Sweden)

    Dussaillant Catalina

    2012-11-01

    Full Text Available Abstract Background Severe hypertriglyceridemia (HTG has been linked to defects in LPL, APOC2, APOA5, LMF1 and GBIHBP1 genes. However, a number of severe HTG cases are probably caused by as yet unidentified mutations. Very high triglyceride plasma levels (>112 mmol/L at diagnosis were found in two sisters of a Chilean consanguineous family, which is strongly suggestive of a recessive highly penetrant mutation. The aim of this study was to determine the genetic locus responsible for the severe HTG in this family. Methods We carried out a genome-wide linkage study with nearly 300,000 biallelic markers (Illumina Human CytoSNP-12 panel. Using the homozygosity mapping strategy, we searched for chromosome regions with excess of homozygous genotypes in the affected cases compared to non-affected relatives. Results A large homozygous segment was found in the long arm of chromosome 11, with more than 2,500 consecutive homozygous SNP shared by the proband with her affected sister, and containing the APOA5/A4/C3/A1 cluster. Direct sequencing of the APOA5 gene revealed a known homozygous nonsense Q97X mutation (p.Gln97Ter found in both affected sisters but not in non-affected relatives nor in a sample of unrelated controls. Conclusion The Q97X mutation of the APOA5 gene in homozygous status is responsible for the severe hypertriglyceridemia in this family. We have shown that homozygosity mapping correctly pinpointed the genomic region containing the gene responsible for severe hypertriglyceridemia in this consanguineous Chilean family.

  6. APOA5 Q97X mutation identified through homozygosity mapping causes severe hypertriglyceridemia in a Chilean consanguineous family.

    Science.gov (United States)

    Dussaillant, Catalina; Serrano, Valentina; Maiz, Alberto; Eyheramendy, Susana; Cataldo, Luis Rodrigo; Chavez, Matías; Smalley, Susan V; Fuentes, Marcela; Rigotti, Attilio; Rubio, Lorena; Lagos, Carlos F; Martinez, José Alfredo; Santos, José Luis

    2012-11-15

    Severe hypertriglyceridemia (HTG) has been linked to defects in LPL, APOC2, APOA5, LMF1 and GBIHBP1 genes. However, a number of severe HTG cases are probably caused by as yet unidentified mutations. Very high triglyceride plasma levels (>112 mmol/L at diagnosis) were found in two sisters of a Chilean consanguineous family, which is strongly suggestive of a recessive highly penetrant mutation. The aim of this study was to determine the genetic locus responsible for the severe HTG in this family. We carried out a genome-wide linkage study with nearly 300,000 biallelic markers (Illumina Human CytoSNP-12 panel). Using the homozygosity mapping strategy, we searched for chromosome regions with excess of homozygous genotypes in the affected cases compared to non-affected relatives. A large homozygous segment was found in the long arm of chromosome 11, with more than 2,500 consecutive homozygous SNP shared by the proband with her affected sister, and containing the APOA5/A4/C3/A1 cluster. Direct sequencing of the APOA5 gene revealed a known homozygous nonsense Q97X mutation (p.Gln97Ter) found in both affected sisters but not in non-affected relatives nor in a sample of unrelated controls. The Q97X mutation of the APOA5 gene in homozygous status is responsible for the severe hypertriglyceridemia in this family. We have shown that homozygosity mapping correctly pinpointed the genomic region containing the gene responsible for severe hypertriglyceridemia in this consanguineous Chilean family.

  7. Unraveling the genetic landscape of autosomal recessive Charcot-Marie-Tooth neuropathies using a homozygosity mapping approach

    Science.gov (United States)

    Zimoń, Magdalena; Battaloǧlu, Esra; Parman, Yesim; Erdem, Sevim; Baets, Jonathan; De Vriendt, Els; Atkinson, Derek; Almeida-Souza, Leonardo; Deconinck, Tine; Ozes, Burcak; Goossens, Dirk; Cirak, Sebahattin; Van Damme, Philip; Shboul, Mohammad; Voit, Thomas; Van Maldergem, Lionel; Dan, Bernard; El-Khateeb, Mohammed S.; Guergueltcheva, Velina; Lopez-Laso, Eduardo; Goemans, Nathalie; Masri, Amira; Züchner, Stephan; Timmerman, Vincent; Topaloǧlu, Haluk; De Jonghe, Peter

    2016-01-01

    Autosomal recessive forms of Charcot-Marie-Tooth disease (ARCMT) are rare but severe disorders of the peripheral nervous system. Their molecular basis is poorly understood due to the extensive genetic and clinical heterogeneity, posing considerable challenges for patients, physicians, and researchers. We report on the genetic findings from a systematic study of a large collection of 174 independent ARCMT families. Initial sequencing of the three most common ARCMT genes (ganglioside-induced differentiation protein 1—GDAP1, SH3 domain and tetratricopeptide repeats-containing protein 2—SH3TC2, histidine-triad nucleotide binding protein 1—HINT1) identified pathogenic mutations in 41 patients. Subsequently, 87 selected nuclear families underwent single nucleotide polymorphism (SNP) genotyping and homozygosity mapping, followed by targeted screening of known ARCMT genes. This strategy provided molecular diagnosis to 22 % of the families. Altogether, our unbiased genetic approach identified pathogenic mutations in ten ARCMT genes in a total of 41.3 % patients. Apart from a newly described founder mutation in GDAP1, the majority of variants constitute private molecular defects. Since the gene testing was independent of the clinical phenotype of the patients, we identified mutations in patients with unusual or additional clinical features, extending the phenotypic spectrum of the SH3TC2 gene. Our study provides an overview of the ARCMT genetic landscape and proposes guidelines for tackling the genetic heterogeneity of this group of hereditary neuropathies. PMID:25231362

  8. The Use of High-Density SNP Array to Map Homozygosity in Consanguineous Families to Efficiently Identify Candidate Genes: Application to Woodhouse-Sakati Syndrome

    Directory of Open Access Journals (Sweden)

    Molly B. Sheridan

    2015-01-01

    Full Text Available Two consanguineous Qatari siblings presented for evaluation: a 17-4/12-year-old male with hypogonadotropic hypogonadism, alopecia, intellectual disability, and microcephaly and his 19-year-old sister with primary amenorrhea, alopecia, and normal cognition. Both required hormone treatment to produce secondary sex characteristics and pubertal development beyond Tanner 1. SNP array analysis of both probands was performed to detect shared regions of homozygosity which may harbor homozygous mutations in a gene causing their common features of abnormal pubertal development, alopecia, and variable cognitive delay. Our patients shared multiple homozygous genomic regions; ten shared regions were >1 Mb in length and constituted 0.99% of the genome. DCAF17, encoding a transmembrane nuclear protein of uncertain function, was the only gene identified in a homozygous region known to cause hypogonadotropic hypogonadism. DCAF17 mutations are associated with Woodhouse-Sakati syndrome, a rare disorder characterized by alopecia, hypogonadotropic hypogonadism, sensorineural hearing loss, diabetes mellitus, and extrapyramidal movements. Sequencing of the coding exons and flanking intronic regions of DCAF17 in the proband revealed homozygosity for a previously described founder mutation (c.436delC. Targeted DCAF17 sequencing of his affected sibling revealed the same homozygous mutation. This family illustrates the utility of SNP array testing in consanguineous families to efficiently and inexpensively identify regions of genomic homozygosity in which genetic candidates for recessive conditions can be identified.

  9. Homozygosity mapping reveals new nonsense mutation in the FAM161A gene causing autosomal recessive retinitis pigmentosa in a Palestinian family.

    Science.gov (United States)

    Zobor, Ditta; Balousha, Ghassan; Baumann, Britta; Wissinger, Bernd

    2014-01-01

    Retinitis pigmentosa (RP) is a heterogenous group of inherited retinal degenerations caused by mutations in at least 45 genes. Recently, the FAM161A gene was identified as the causative gene for RP28, an autosomal recessive form of RP. We performed a clinical and molecular genetic study of a consanguineous Palestinian family with two three siblings affected with retinitis pigmentosa. DNA samples were collected from the index patient, his father, his affected sister, and two non-affected brothers. DNA sample from the index was subjected to high resolution genome-wide SNP array. Assuming identity-by-descent in this consanguineous family we applied homozygosity mapping to identify disease causing genes. The index patient reported night blindness since the age of 20 years, followed by moderate disease progression with decrease of peripheral vision, the development of photophobia and later on reduced central vision. At the age of 40 his visual acuity was counting fingers (CF) for both eyes, color discrimination was not possible and his visual fields were severely constricted. Funduscopic examination revealed a typical appearance of advanced RP with optic disc pallor, narrowed retinal vessels, bone-spicule like pigmentary changes in the mid-periphery and atrophic changes in the macula. His younger affected brother (37 years) was reported with overall milder symptoms, while the youngest sister (21 years) reported problems only with night vision. Applying high-density SNP arrays we identified several homozygous genomic regions one of which included the recently identified FAM161A gene mutated in RP28-linked autosomal recessive RP. Sequencing analysis revealed the presence of a novel homozygous nonsense mutation, c.1003C>T/p.R335X in the index patient and the affected sister. We identified an RP28-linked RP family in the Palestinian population caused by a novel nonsense mutation in FAM161A. RP in this family shows a typical disease onset with moderate to rapid progression

  10. Mapping Intermediality in Performance

    NARCIS (Netherlands)

    2010-01-01

    Mapping Intermediality in Performance benadert het vraagstuk van intermedialiteit met betrekking tot performance (vooral theater) vanuit vijf verschillende invalshoeken: performativiteit en lichaam; tijd en ruimte; digitale cultuur en posthumanisme; netwerken; pedagogiek en praxis. In deze boeiende

  11. Screening for homozygosity by descent in families with autosomal

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics; Volume 81; Issue 2 ... Perspectives Volume 81 Issue 2 August 2002 pp 59-63 ... disease locus in families with the recessive form of the disease, we used the approach of screening for homozygosity by descent in offspring of consanguineous and nonconsanguineous families with RP.

  12. CRESST Human Performance Knowledge Mapping System

    National Research Council Canada - National Science Library

    Chung, Gregory K; Michiuye, Joanne K; Brill, David G; Sinha, Ravi; Saadat, Farzad; de Vries, Linda F; Delacruz, Girlie C; Bewley, William L; Baker, Eva L

    2002-01-01

    .... While several tools exist that are available to construct knowledge maps, CRESST's knowledge mapping tool is one of the only systems designed specifically for assessment purposes, the only system...

  13. CRESST Human Performance Knowledge Mapping System

    National Research Council Canada - National Science Library

    Chung, Gregory K; Michiuye, Joanne K; Brill, David G; Sinha, Ravi; Saadat, Farzad; de Vries, Linda F; Delacruz, Girlie C; Bewley, William L; Baker, Eva L

    2002-01-01

    .... This report presents a review of knowledge mapping scoring methods and current online mapping systems, and the overall design, functionality, scoring, usability testing, and authoring capabilities of the CRESST system...

  14. Homozygosity and risk of childhood death due to invasive bacterial disease

    Directory of Open Access Journals (Sweden)

    Williams Thomas N

    2009-06-01

    Full Text Available Abstract Background Genetic heterozygosity is increasingly being shown to be a key predictor of fitness in natural populations, both through inbreeding depression, inbred individuals having low heterozygosity, and also through chance linkage between a marker and a gene under balancing selection. One important component of fitness that is often highlighted is resistance to parasites and other pathogens. However, the significance of equivalent loci in human populations remains unclear. Consequently, we performed a case-control study of fatal invasive bacterial disease in Kenyan children using a genome-wide screen with microsatellite markers. Methods 148 cases, comprising children aged Results At five markers homozygosity was strongly associated with mortality (odds ratio range 4.7 – 12.2 with evidence of interactions between some markers. Mortality was associated with different non-overlapping marker groups in Gram positive and Gram negative bacterial disease. Homozygosity at susceptibility markers was common (prevalence 19–49% and, with the large effect sizes, this suggests that bacterial disease mortality may be strongly genetically determined. Conclusion Balanced polymorphisms appear to be more widespread in humans than previously appreciated and play a critical role in modulating susceptibility to infectious disease. The effect sizes we report, coupled with the stochasticity of exposure to pathogens suggests that infection and mortality are far from random due to a strong genetic basis.

  15. Performance analysis of different database in new internet mapping system

    Science.gov (United States)

    Yao, Xing; Su, Wei; Gao, Shuai

    2017-03-01

    In the Mapping System of New Internet, Massive mapping entries between AID and RID need to be stored, added, updated, and deleted. In order to better deal with the problem when facing a large number of mapping entries update and query request, the Mapping System of New Internet must use high-performance database. In this paper, we focus on the performance of Redis, SQLite, and MySQL these three typical databases, and the results show that the Mapping System based on different databases can adapt to different needs according to the actual situation.

  16. Performing Mimetic Mapping: A Non-Visualisable Map of the Suzhou River Area of Shanghai

    Directory of Open Access Journals (Sweden)

    Anastasia Karandinou

    2014-07-01

    Full Text Available This paper questions issues concerning the mapping of experience, through the concept of mimesis – the creative re-performance of the site experience onto the map. The place mapped is the Suzhou River area, a significant part of Shanghai, the former boundary between the British and American Settlements, and an ever-changing and transforming territory. Through the detailed description of the mapping processes, we analyse the position of this particular map within contemporary discourse about mapping. Here, we question the purpose of the process, the desired outcome, the consciousness of the significance of each step/event, and the possible significance of the final traces that the mapping leaves behind. Although after the mapping had been carried out, the procedure was analysed, post-rationalised, and justified through its partial documentation (as part of an educational process, this paper questions the way and the reason for these practices (the post-rationalising of the mapping activity, justifying the strategy, etc., and their possible meaning, purpose, demand or context. Thus we conclude that the subject matter is not the final outcome of an object or ‘map’; there is no final map to be exhibited. What this paper brings forth is the mapping as an event, an action performed by the embodied experience of the actual place and by the trans-local materiality of the tools and elements involved in the process of its making.

  17. Crime clocks and target performance maps

    CSIR Research Space (South Africa)

    Cooper, Antony K

    1999-12-01

    Full Text Available the period of analysis. Each segment of a pie chart represents a selected part of the day (eg: a two- or three-hour period) or a day of the week. The first and last segments in the day or week are then adjacent, ensuring that there is no artificial break... clocks We have also used crime clocks to map the proportion of crimes that occur during normal police working hours (07:00 to 16:00, Monday to Friday, in the case of the Johannesburg Area), against those that occur outside these hours. 3. Target...

  18. The CMS Magnetic Field Map Performance

    CERN Document Server

    Klyukhin, V.I.; Andreev, V.; Ball, A.; Cure, B.; Herve, A.; Gaddi, A.; Gerwig, H.; Karimaki, V.; Loveless, R.; Mulders, M.; Popescu, S.; Sarycheva, L.I.; Virdee, T.

    2010-04-05

    The Compact Muon Solenoid (CMS) is a general-purpose detector designed to run at the highest luminosity at the CERN Large Hadron Collider (LHC). Its distinctive featuresinclude a 4 T superconducting solenoid with 6 m diameter by 12.5 m long free bore, enclosed inside a 10000-ton return yoke made of construction steel. Accurate characterization of the magnetic field everywhere in the CMS detector is required. During two major tests of the CMS magnet the magnetic flux density was measured inside the coil in a cylinder of 3.448 m diameter and 7 m length with a specially designed field-mapping pneumatic machine as well as in 140 discrete regions of the CMS yoke with NMR probes, 3-D Hall sensors and flux-loops. A TOSCA 3-D model of the CMS magnet has been developed to describe the magnetic field everywhere outside the tracking volume measured with the field-mapping machine. A volume based representation of the magnetic field is used to provide the CMS simulation and reconstruction software with the magnetic field ...

  19. Performance maps for the control of thermal energy storage

    DEFF Research Database (Denmark)

    Finck, Christian; Li, Rongling; Zeiler, Wim

    2017-01-01

    Predictive control in building energy systems requires the integration of the building, building system, and component dynamics. The prediction accuracy of these dynamics is crucial for practical applications. This paper introduces performance maps for the control of water tanks, phase change mat...... material tanks, and thermochemical material tanks. The results show that these performance maps can fully account for the dynamics of thermal energy storage tanks.......Predictive control in building energy systems requires the integration of the building, building system, and component dynamics. The prediction accuracy of these dynamics is crucial for practical applications. This paper introduces performance maps for the control of water tanks, phase change...

  20. Insights into earthquake hazard map performance from shaking history simulations

    Science.gov (United States)

    Stein, S.; Vanneste, K.; Camelbeeck, T.; Vleminckx, B.

    2017-12-01

    Why recent large earthquakes caused shaking stronger than predicted by earthquake hazard maps is under debate. This issue has two parts. Verification involves how well maps implement probabilistic seismic hazard analysis (PSHA) ("have we built the map right?"). Validation asks how well maps forecast shaking ("have we built the right map?"). We explore how well a map can ideally perform by simulating an area's shaking history and comparing "observed" shaking to that predicted by a map generated for the same parameters. The simulations yield shaking distributions whose mean is consistent with the map, but individual shaking histories show large scatter. Infrequent large earthquakes cause shaking much stronger than mapped, as observed. Hence, PSHA seems internally consistent and can be regarded as verified. Validation is harder because an earthquake history can yield shaking higher or lower than that predicted while being consistent with the hazard map. The scatter decreases for longer observation times because the largest earthquakes and resulting shaking are increasingly likely to have occurred. For the same reason, scatter is much less for the more active plate boundary than for a continental interior. For a continental interior, where the mapped hazard is low, even an M4 event produces exceedances at some sites. Larger earthquakes produce exceedances at more sites. Thus many exceedances result from small earthquakes, but infrequent large ones may cause very large exceedances. However, for a plate boundary, an M6 event produces exceedance at only a few sites, and an M7 produces them in a larger, but still relatively small, portion of the study area. As reality gives only one history, and a real map involves assumptions about more complicated source geometries and occurrence rates, which are unlikely to be exactly correct and thus will contribute additional scatter, it is hard to assess whether misfit between actual shaking and a map — notably higher-than-mapped

  1. Mapping strategy, structure, ownership and performance in European corporations : Introduction

    NARCIS (Netherlands)

    Colli, A.; Iversen, M.J.; de Jong, A.

    2011-01-01

    This paper is the introduction to the Business History special issue on European Business Models. The volume presents results of the international project about mapping European corporations, within the strategy, structure, ownership and performance (SSOP) framework. The paper describes the

  2. Stirling convertor performance mapping test results

    Science.gov (United States)

    Qiu, Songgang; Peterson, Allen A.; White, Maurice A.; Faultersack, Franklyn; Redinger, Darin L.; Petersen, Stephen L.

    2002-01-01

    The Department of Energy (DOE) has selected Free-Piston Stirling Convertors as a technology for future advanced radioisotope space power systems. In August 2000, DOE awarded competitive Phase I, Stirling Radioisotope Generator (SRG) power system integration contracts to three major aerospace contractors, resulting in SRG conceptual designs in February 2001. All three contractors based their designs on the Technology Demonstration Convertor (TDC) developed by Stirling Technology Company (STC) for DOE. The contract award to a single system integration contractor for Phases II and III of the SRG program is anticipated in late 2001. The first potential SRG mission is targeted for a Mars rover. Recent TDC performance data are provided in this paper, together with predictions from Stirling simulation models. .

  3. UPD detection using homozygosity profiling with a SNP genotyping microarray.

    Science.gov (United States)

    Papenhausen, Peter; Schwartz, Stuart; Risheg, Hiba; Keitges, Elisabeth; Gadi, Inder; Burnside, Rachel D; Jaswaney, Vikram; Pappas, John; Pasion, Romela; Friedman, Kenneth; Tepperberg, James

    2011-04-01

    Single nucleotide polymorphism (SNP) based chromosome microarrays provide both a high-density whole genome analysis of copy number and genotype. In the past 21 months we have analyzed over 13,000 samples primarily referred for developmental delay using the Affymetrix SNP/CN 6.0 version array platform. In addition to copy number, we have focused on the relative distribution of allele homozygosity (HZ) throughout the genome to confirm a strong association of uniparental disomy (UPD) with regions of isoallelism found in most confirmed cases of UPD. We sought to determine whether a long contiguous stretch of HZ (LCSH) greater than a threshold value found only in a single chromosome would correlate with UPD of that chromosome. Nine confirmed UPD cases were retrospectively analyzed with the array in the study, each showing the anticipated LCSH with the smallest 13.5 Mb in length. This length is well above the average longest run of HZ in a set of control patients and was then set as the prospective threshold for reporting possible UPD correlation. Ninety-two cases qualified at that threshold, 46 of those had molecular UPD testing and 29 were positive. Including retrospective cases, 16 showed complete HZ across the chromosome, consistent with total isoUPD. The average size LCSH in the 19 cases that were not completely HZ was 46.3 Mb with a range of 13.5-127.8 Mb. Three patients showed only segmental UPD. Both the size and location of the LCSH are relevant to correlation with UPD. Further studies will continue to delineate an optimal threshold for LCSH/UPD correlation. Copyright © 2011 Wiley-Liss, Inc.

  4. MAPS evaluation report and procedures governing interviews and performance appraisals

    CERN Multimedia

    HR Department

    2006-01-01

    Following various improvements to the MAPS report and to the procedures governing interviews and performance appraisals (announced in the CERN Bulletin 48-49/2005), a third information session has been organized for all staff members on Tuesday, 31 January at 10 a.m.: AB Auditorium P (864-1-D02), Human Resources Department Tel. 73566

  5. Systematic mapping review on student's performance analysis using ...

    African Journals Online (AJOL)

    This paper classify the various existing predicting models that are used for monitoring and improving students' performance at schools and higher learning institutions. It analyses all the areas within the educational data mining methodology. Two databases were chosen for this study and a systematic mapping study was ...

  6. How Concept-Mapping Perception Navigates Student Knowledge Transfer Performance

    Science.gov (United States)

    Tseng, Kuo-Hung; Chang, Chi-Cheng; Lou, Shi-Jer; Tan, Yue; Chiu, Chien-Jung

    2012-01-01

    The purpose of this paper is to investigate students' perception of concept maps as a learning tool where knowledge transfer is the goal. This article includes an evaluation of the learning performance of 42 undergraduate students enrolled in a nanotech course at a university in Taiwan. Canonical correlation and MANOVA analyses were employed to…

  7. Comparing the performance of various digital soil mapping approaches to map physical soil properties

    Science.gov (United States)

    Laborczi, Annamária; Takács, Katalin; Pásztor, László

    2015-04-01

    digital soil mapping methods and sets of ancillary variables for producing the most accurate spatial prediction of texture classes in a given area of interest. Both legacy and recently collected data on PSD were used as reference information. The predictor variable data set consisted of digital elevation model and its derivatives, lithology, land use maps as well as various bands and indices of satellite images. Two conceptionally different approaches can be applied in the mapping process. Textural classification can be realized after particle size data were spatially extended by proper geostatistical method. Alternatively, the textural classification is carried out first, followed by the spatial extension through suitable data mining method. According to the first approach, maps of sand, silt and clay percentage have been computed through regression kriging (RK). Since the three maps are compositional (their sum must be 100%), we applied Additive Log-Ratio (alr) transformation, instead of kriging them independently. Finally, the texture class map has been compiled according to the USDA categories from the three maps. Different combinations of reference and training soil data and auxiliary covariables resulted several different maps. On the basis of the other way, the PSD were classified firstly into the USDA categories, then the texture class maps were compiled directly by data mining methods (classification trees and random forests). The various results were compared to each other as well as to the RK maps. The performance of the different methods and data sets has been examined by testing the accuracy of the geostatistically computed and the directly classified results to assess the most predictive and accurate method. Acknowledgement: Our work was supported by the Hungarian National Scientific Research Foundation (OTKA, Grant No. K105167).

  8. Proficient brain for optimal performance: the MAP model perspective.

    Science.gov (United States)

    Bertollo, Maurizio; di Fronso, Selenia; Filho, Edson; Conforto, Silvia; Schmid, Maurizio; Bortoli, Laura; Comani, Silvia; Robazza, Claudio

    2016-01-01

    Background. The main goal of the present study was to explore theta and alpha event-related desynchronization/synchronization (ERD/ERS) activity during shooting performance. We adopted the idiosyncratic framework of the multi-action plan (MAP) model to investigate different processing modes underpinning four types of performance. In particular, we were interested in examining the neural activity associated with optimal-automated (Type 1) and optimal-controlled (Type 2) performances. Methods. Ten elite shooters (6 male and 4 female) with extensive international experience participated in the study. ERD/ERS analysis was used to investigate cortical dynamics during performance. A 4 × 3 (performance types × time) repeated measures analysis of variance was performed to test the differences among the four types of performance during the three seconds preceding the shots for theta, low alpha, and high alpha frequency bands. The dependent variables were the ERD/ERS percentages in each frequency band (i.e., theta, low alpha, high alpha) for each electrode site across the scalp. This analysis was conducted on 120 shots for each participant in three different frequency bands and the individual data were then averaged. Results. We found ERS to be mainly associated with optimal-automatic performance, in agreement with the "neural efficiency hypothesis." We also observed more ERD as related to optimal-controlled performance in conditions of "neural adaptability" and proficient use of cortical resources. Discussion. These findings are congruent with the MAP conceptualization of four performance states, in which unique psychophysiological states underlie distinct performance-related experiences. From an applied point of view, our findings suggest that the MAP model can be used as a framework to develop performance enhancement strategies based on cognitive and neurofeedback techniques.

  9. Proficient brain for optimal performance: the MAP model perspective

    Directory of Open Access Journals (Sweden)

    Maurizio Bertollo

    2016-05-01

    Full Text Available Background. The main goal of the present study was to explore theta and alpha event-related desynchronization/synchronization (ERD/ERS activity during shooting performance. We adopted the idiosyncratic framework of the multi-action plan (MAP model to investigate different processing modes underpinning four types of performance. In particular, we were interested in examining the neural activity associated with optimal-automated (Type 1 and optimal-controlled (Type 2 performances. Methods. Ten elite shooters (6 male and 4 female with extensive international experience participated in the study. ERD/ERS analysis was used to investigate cortical dynamics during performance. A 4 × 3 (performance types × time repeated measures analysis of variance was performed to test the differences among the four types of performance during the three seconds preceding the shots for theta, low alpha, and high alpha frequency bands. The dependent variables were the ERD/ERS percentages in each frequency band (i.e., theta, low alpha, high alpha for each electrode site across the scalp. This analysis was conducted on 120 shots for each participant in three different frequency bands and the individual data were then averaged. Results. We found ERS to be mainly associated with optimal-automatic performance, in agreement with the “neural efficiency hypothesis.” We also observed more ERD as related to optimal-controlled performance in conditions of “neural adaptability” and proficient use of cortical resources. Discussion. These findings are congruent with the MAP conceptualization of four performance states, in which unique psychophysiological states underlie distinct performance-related experiences. From an applied point of view, our findings suggest that the MAP model can be used as a framework to develop performance enhancement strategies based on cognitive and neurofeedback techniques.

  10. New modified map for digital image encryption and its performance

    Science.gov (United States)

    Suryadi, MT; Yus Trinity Irsan, Maria; Satria, Yudi

    2017-10-01

    Protection to classified digital data becomes so important in avoiding data manipulation and alteration. The focus of this paper is in data and information protection of digital images form. Protection is provided in the form of encrypted digital image. The encryption process uses a new map, {x}n+1=\\frac{rλ {x}n}{1+λ {(1-{x}n)}2}\\quad ({mod} 1), which is called MS map. This paper will show: the results of digital image encryption using MS map and how the performance is regarding the average time needed for encryption/decryption process; randomness of key stream sequence with NIST test, histogram analysis and goodness of fit test, quality of the decrypted image by PSNR, initial value sensitivity level, and key space. The results show that the average time of the encryption process is relatively same as the decryption process and it depends to types and sizes of the image. Cipherimage (encrypted image) is uniformly distributed since: it passes the goodness of fit test and also the histogram of the cipherimage is flat; key stream, that are generated by MS map, passes frequency (monobit) test, and runs test, which means the key stream is a random sequence; the decrypted image has same quality as the original image; and initial value sensitivity reaches 10-17, and key space reaches 3.24 × 10634. So, that encryption algorithm generated by MS map is more resistant to brute-force attack and known plaintext attack.

  11. Performance Evaluation of Java Based Object Relational Mapping Tools

    Directory of Open Access Journals (Sweden)

    Shoaib Mahmood Bhatti

    2013-04-01

    Full Text Available Object persistency is the hot issue in the form of ORM (Object Relational Mapping tools in industry as developers use these tools during software development. This paper presents the performance evaluation of Java based ORM tools. For this purpose, Hibernate, Ebean and TopLinkhave been selected as the ORM tools which are popular and open source. Their performance has been measured from execution point of view. The results show that ORM tools are the good option for the developers considering the system throughput in shorter setbacks and they can be used efficiently and effectively for performing mapping of the objects into the relational dominated world of database, thus creating a hope for a better and well dominated future of this technology.

  12. Extended tracts of homozygosity identify novel candidate genes associated with late onset Alzheimer’s Disease

    Science.gov (United States)

    Nalls, M. A.; Guerreiro, R. J.; Simon-Sanchez, J.; Bras, J. T.; Traynor, B. J.; Gibbs, J. R.; Launer, L.; Hardy, J.; Singleton, A. B.

    2010-01-01

    Large tracts of extended homozygosity are more prevalent in outbred populations than previously thought. With the advent of high-density genotyping platforms, regions of extended homozygosity can be accurately located allowing for the identification of rare recessive risk variants contributing to disease. We compared measures of extended homozygosity (greater than 1 megabase in length) in a population of 837 late onset Alzheimer’s disease (LOAD) cases and 550 controls. In our analyses, we identify one homozygous region on chromosome 8 that is significantly associated with LOAD after adjusting for multiple testing. This region contains seven genes from which the most biologically plausible candidates are STAR, EIF4EBP1 and ADRB3. We also compared the total numbers of homozygous runs and the total length of these runs between cases and controls, showing a suggestive difference in these measures (p-values 0.052-0.062). This research suggests a recessive component to the etiology of LOAD. PMID:19271249

  13. MAPS evaluation report and procedures governing interviews and performance appraisals

    CERN Multimedia

    HR Department

    2006-01-01

    Following various improvements made to the MAPS report and to the procedures governing interviews and performance appraisals (announced in the CERN Weekly Bulletin 48-49/2005), three information sessions have been organized for all staff members: 24 January 10:00: AB Auditorium P (864-1-D02), 26 January 14:00: Main Amphitheatre, 31 January 10:00: AB Auditorium P (864-1-D02). Human Resources Department Tel. 73566

  14. Negative screening tests in classical galactosaemia caused by S135L homozygosity.

    LENUS (Irish Health Repository)

    Crushell, E

    2009-06-01

    Classical galactosaemia is relatively common in Ireland due to a high carrier rate of the Q188R GALT mutation. It is screened for using a bacterial inhibition assay (BIA) for free galactose. A Beutler assay on day one of life is performed only in high risk cases (infants of the Traveller community and relatives of known cases). A 16-month-old Irish-born boy of Nigerian origin was referred for investigation of developmental delay, and failure to thrive. He had oral aversion to solids and his diet consisted of cow\\'s milk and milk-based cereal mixes. He was found to have microcephaly, weight <2nd percentile, hepatomegaly and bilateral cataracts. Coagulation screen was normal and transaminases were slightly elevated. His original newborn screen was reviewed and confirmed to have been negative; urinary reducing substances on three separate occasions were negative. Beutler assay demonstrated "absent" red cell galactose-1-phosphate uridyltransferase (GALT) activity. GALT enzyme activity was <0.5 gsubs\\/h per gHb confirming classical galactosaemia. Gal-1-P was elevated at 1.88 micromol\\/gHb. Mutation analysis of the GALT gene revealed S135L homozygosity. S135L\\/S135L galactosaemia is associated with absent red cell GALT activity but with approximately 10% activity in other tissues such as the liver and intestines, probably explaining the negative screening tests and the somewhat milder phenotype associated with this genotype. The patient was commenced on galactose-restricted diet; on follow-up at 2 years of age, growth had normalized but there was global developmental delay. In conclusion, galactosaemia must be considered in children who present with poor growth, hepatomegaly, developmental delay and cataracts and GALT enzyme analysis should be a first line test in such cases. Non-enzymatic screening methods such as urinary reducing substances and BIA for free galactose are not reliable in S135L homozygous galactosaemia.

  15. Runs of homozygosity and distribution of functional variants in cattle genome

    DEFF Research Database (Denmark)

    Zhang, Qianqian; Guldbrandtsen, Bernt; Bosse, Mirte

    Runs of homozygosity (ROH) are identified in four dairy cattle breeds using NGS data. Cattle populations have been exposed to strong artificial selection for some generations. Genomic regions under selection will show increased levels of ROH. By investigating the relationship between ROH and dist......Runs of homozygosity (ROH) are identified in four dairy cattle breeds using NGS data. Cattle populations have been exposed to strong artificial selection for some generations. Genomic regions under selection will show increased levels of ROH. By investigating the relationship between ROH...... and distribution of predicted deleterious and tolerated variants, we can gain insight into how selection shapes the distribution of functional variants in inbred regions. We observe that predicted deleterious variants are more enriched in ROHs than predicted tolerated variants. Moreover, increase of enrichment...

  16. Effects of supervised Self Organising Maps parameters on classification performance.

    Science.gov (United States)

    Ballabio, Davide; Vasighi, Mahdi; Filzmoser, Peter

    2013-02-26

    Self Organising Maps (SOMs) are one of the most powerful learning strategies among neural networks algorithms. SOMs have several adaptable parameters and the selection of appropriate network architectures is required in order to make accurate predictions. The major disadvantage of SOMs is probably due to the network optimisation, since this procedure can be often time-expensive. Effects of network size, training epochs and learning rate on the classification performance of SOMs are known, whereas the effect of other parameters (type of SOMs, weights initialisation, training algorithm, topology and boundary conditions) are not so obvious. This study was addressed to analyse the effect of SOMs parameters on the network classification performance, as well as on their computational times, taking into consideration a significant number of real datasets, in order to achieve a comprehensive statistical comparison. Parameters were contemporaneously evaluated by means of an approach based on the design of experiments, which enabled the investigation of their interaction effects. Results highlighted the most important parameters which influence the classification performance and enabled the identification of the optimal settings, as well as the optimal architectures to reduce the computational time of SOMs. Copyright © 2012 Elsevier B.V. All rights reserved.

  17. Geoelectrical mapping for improved performance of SUDS in clay tills

    DEFF Research Database (Denmark)

    Bockhorn, Britta; Møller, Ingelise; Klint, Knud Erik S.

    2015-01-01

    geological methods, including borehole soil sample descriptions, one excavation description and a near-surface spear auger-mapping project. The experiments returned a significant correlation of geoelectrical and spear auger-mapped surface sediments. Furthermore, a highly permeable oxidized fracture zone...

  18. Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals

    Science.gov (United States)

    Ghani, Mahdi; Reitz, Christiane; Cheng, Rong; Vardarajan, Badri Narayan; Jun, Gyungah; Sato, Christine; Naj, Adam; Rajbhandary, Ruchita; Wang, Li-San; Valladares, Otto; Lin, Chiao-Feng; Larson, Eric B.; Graff-Radford, Neill R.; Evans, Denis; De Jager, Philip L.; Crane, Paul K.; Buxbaum, Joseph D.; Murrell, Jill R.; Raj, Towfique; Ertekin-Taner, Nilufer; Logue, Mark; Baldwin, Clinton T.; Green, Robert C.; Barnes, Lisa L.; Cantwell, Laura B.; Fallin, M. Daniele; Go, Rodney C. P.; Griffith, Patrick A.; Obisesan, Thomas O.; Manly, Jennifer J.; Lunetta, Kathryn L.; Kamboh, M. Ilyas; Lopez, Oscar L.; Bennett, David A.; Hendrie, Hugh; Hall, Kathleen S.; Goate, Alison M.; Byrd, Goldie S.; Kukull, Walter A.; Foroud, Tatiana M.; Haines, Jonathan L.; Farrer, Lindsay A.; Pericak-Vance, Margaret A.; Lee, Joseph H.; Schellenberg, Gerard D.; St. George-Hyslop, Peter; Mayeux, Richard; Rogaeva, Ekaterina

    2015-01-01

    IMPORTANCE Mutations in known causal Alzheimer disease (AD) genes account for only 1% to 3% of patients and almost all are dominantly inherited. Recessive inheritance of complex phenotypes can be linked to long (>1-megabase [Mb]) runs of homozygosity (ROHs) detectable by single-nucleotide polymorphism (SNP) arrays. OBJECTIVE To evaluate the association between ROHs and AD in an African American population known to have a risk for AD up to 3 times higher than white individuals. DESIGN, SETTING, AND PARTICIPANTS Case-control study of a large African American data set previously genotyped on different genome-wide SNP arrays conducted from December 2013 to January 2015. Global and locus-based ROH measurements were analyzed using raw or imputed genotype data. We studied the raw genotypes from 2 case-control subsets grouped based on SNP array: Alzheimer’s Disease Genetics Consortium data set (871 cases and 1620 control individuals) and Chicago Health and Aging Project–Indianapolis Ibadan Dementia Study data set (279 cases and 1367 control individuals). We then examined the entire data set using imputed genotypes from 1917 cases and 3858 control individuals. MAIN OUTCOMES AND MEASURES The ROHs larger than 1 Mb, 2 Mb, or 3 Mb were investigated separately for global burden evaluation, consensus regions, and gene-based analyses. RESULTS The African American cohort had a low degree of inbreeding (F ~ 0.006). In the Alzheimer’s Disease Genetics Consortium data set, we detected a significantly higher proportion of cases with ROHs greater than 2 Mb (P = .004) or greater than 3 Mb (P = .02), as well as a significant 114-kilobase consensus region on chr4q31.3 (empirical P value 2 = .04; ROHs >2 Mb). In the Chicago Health and Aging Project–Indianapolis Ibadan Dementia Study data set, we identified a significant 202-kilobase consensus region on Chr15q24.1 (empirical P value 2 = .02; ROHs >1 Mb) and a cluster of 13 significant genes on Chr3p21.31 (empirical P value 2 = .03

  19. Educational Attainment Influences Levels of Homozygosity through Migration and Assortative Mating

    Science.gov (United States)

    Abdellaoui, Abdel; Hottenga, Jouke-Jan; Willemsen, Gonneke; Bartels, Meike; van Beijsterveldt, Toos; Ehli, Erik A.; Davies, Gareth E.; Brooks, Andrew; Sullivan, Patrick F.; Penninx, Brenda W. J. H.; de Geus, Eco J.; Boomsma, Dorret I.

    2015-01-01

    Individuals with a higher education are more likely to migrate, increasing the chance of meeting a spouse with a different ancestral background. In this context, the presence of strong educational assortment can result in greater ancestry differences within more educated spouse pairs, while less educated individuals are more likely to mate with someone with whom they share more ancestry. We examined the association between educational attainment and F roh (= the proportion of the genome consisting of runs of homozygosity [ROHs]) in ~2,000 subjects of Dutch ancestry. The subjects’ own educational attainment showed a nominally significant negative association with F roh (p = .045), while the contribution of parental education to offspring F roh was highly significant (father: p migration rates among more educated parents. Parental education also showed a high spouse correlation (Spearman’s ρ = .66, p = 3 × 10-262). We show that less educated parents are less likely to mate with the more mobile parents with a higher education, creating systematic differences in homozygosity due to ancestry differences not directly captured by ancestry-informative principal components (PCs). Understanding how behaviors influence the genomic structure of a population is highly valuable for studies on the genetic etiology of behavioral, cognitive, and social traits. PMID:25734509

  20. Reducing Communication Overhead by Scheduling TCP Transfers on Mobile Devices using Wireless Network Performance Maps

    DEFF Research Database (Denmark)

    Højgaard-Hansen, Kim; Madsen, Tatiana Kozlova; Schwefel, Hans-Peter

    2012-01-01

    The performance of wireless communication networks has been shown to have a strong location dependence. Measuring the performance while having accurate location information available makes it possible to generate performance maps. In this paper we propose a framework for the generation and use...... of such performance maps. We demonstrate how the framework can be used to reduce the retransmissions and to better utilise network resources when performing TCP-based file downloads in vehicular M2M communication scenarios. The approach works on top of a standard TCP stack hence has to map identified transmission...

  1. Effects of Concept Mapping Strategy on Learning Performance in Business and Economics Statistics

    Science.gov (United States)

    Chiou, Chei-Chang

    2009-01-01

    A concept map (CM) is a hierarchically arranged, graphic representation of the relationships among concepts. Concept mapping (CMING) is the process of constructing a CM. This paper examines whether a CMING strategy can be useful in helping students to improve their learning performance in a business and economics statistics course. A single…

  2. The Use of Causal Mapping in the Design of Sustainability Performance Measurement Systems

    DEFF Research Database (Denmark)

    Parisi, Cristiana

    2013-01-01

    organisations’ strategic performance measurement systems (SPMSs). This study’s main contribution is the triangulation of multiple qualitative methods to enhance the reliability of causal maps. This innovative approach supports the use of causal mapping to extract managerial tacit knowledge in order to identify...

  3. Enhancing the mathematical properties of new haplotype homozygosity statistics for the detection of selective sweeps.

    Science.gov (United States)

    Garud, Nandita R; Rosenberg, Noah A

    2015-06-01

    Soft selective sweeps represent an important form of adaptation in which multiple haplotypes bearing adaptive alleles rise to high frequency. Most statistical methods for detecting selective sweeps from genetic polymorphism data, however, have focused on identifying hard selective sweeps in which a favored allele appears on a single haplotypic background; these methods might be underpowered to detect soft sweeps. Among exceptions is the set of haplotype homozygosity statistics introduced for the detection of soft sweeps by Garud et al. (2015). These statistics, examining frequencies of multiple haplotypes in relation to each other, include H12, a statistic designed to identify both hard and soft selective sweeps, and H2/H1, a statistic that conditional on high H12 values seeks to distinguish between hard and soft sweeps. A challenge in the use of H2/H1 is that its range depends on the associated value of H12, so that equal H2/H1 values might provide different levels of support for a soft sweep model at different values of H12. Here, we enhance the H12 and H2/H1 haplotype homozygosity statistics for selective sweep detection by deriving the upper bound on H2/H1 as a function of H12, thereby generating a statistic that normalizes H2/H1 to lie between 0 and 1. Through a reanalysis of resequencing data from inbred lines of Drosophila, we show that the enhanced statistic both strengthens interpretations obtained with the unnormalized statistic and leads to empirical insights that are less readily apparent without the normalization. Copyright © 2015 Elsevier Inc. All rights reserved.

  4. Regions of homozygosity in the porcine genome: consequence of demography and the recombination landscape.

    Directory of Open Access Journals (Sweden)

    Mirte Bosse

    Full Text Available Inbreeding has long been recognized as a primary cause of fitness reduction in both wild and domesticated populations. Consanguineous matings cause inheritance of haplotypes that are identical by descent (IBD and result in homozygous stretches along the genome of the offspring. Size and position of regions of homozygosity (ROHs are expected to correlate with genomic features such as GC content and recombination rate, but also direction of selection. Thus, ROHs should be non-randomly distributed across the genome. Therefore, demographic history may not fully predict the effects of inbreeding. The porcine genome has a relatively heterogeneous distribution of recombination rate, making Sus scrofa an excellent model to study the influence of both recombination landscape and demography on genomic variation. This study utilizes next-generation sequencing data for the analysis of genomic ROH patterns, using a comparative sliding window approach. We present an in-depth study of genomic variation based on three different parameters: nucleotide diversity outside ROHs, the number of ROHs in the genome, and the average ROH size. We identified an abundance of ROHs in all genomes of multiple pigs from commercial breeds and wild populations from Eurasia. Size and number of ROHs are in agreement with known demography of the populations, with population bottlenecks highly increasing ROH occurrence. Nucleotide diversity outside ROHs is high in populations derived from a large ancient population, regardless of current population size. In addition, we show an unequal genomic ROH distribution, with strong correlations of ROH size and abundance with recombination rate and GC content. Global gene content does not correlate with ROH frequency, but some ROH hotspots do contain positive selected genes in commercial lines and wild populations. This study highlights the importance of the influence of demography and recombination on homozygosity in the genome to understand

  5. RELATION OF INBREEDING OF HORSES OF THOROUGHBRED BREED WITH DEGREE OF HOMOZYGOSITY OF MICROSATELLITE LOCI OF DNA

    Directory of Open Access Journals (Sweden)

    Melnyk О.V.

    2013-09-01

    Full Text Available The degree of homozygosity of some 39 Thoroughbred horses was estimated from microsatellite analysis data. The power of inbreeding was detected towards horse pedigree. We suggested the use of genetic analysis of microsatellite loci of DNA for the determination of actual level of inbreeding.

  6. Addressing the Influence of Hidden State on Wireless Network Optimizations using Performance Maps

    DEFF Research Database (Denmark)

    Højgaard-Hansen, Kim; Madsen, Tatiana Kozlova; Schwefel, Hans-Peter

    2015-01-01

    be used to optimize the use of the wireless net- work by predicting future network performance and scheduling the net- work communication for certain applications on mobile devices. However, other important factors influence the performance of the wireless communication such as changes in the propagation...... environment and resource sharing. In this work we extend the framework of performance maps for wireless networks by introducing network state as an abstraction for all other factors than location that influence the performance. Since network state might not always be directly observable the framework......Performance of wireless connectivity for network client devices is location dependent. It has been shown that it can be beneficial to collect network performance metrics along with location information to generate maps of the location dependent network performance. These performance maps can...

  7. MaMR: High-performance MapReduce programming model for material cloud applications

    Science.gov (United States)

    Jing, Weipeng; Tong, Danyu; Wang, Yangang; Wang, Jingyuan; Liu, Yaqiu; Zhao, Peng

    2017-02-01

    With the increasing data size in materials science, existing programming models no longer satisfy the application requirements. MapReduce is a programming model that enables the easy development of scalable parallel applications to process big data on cloud computing systems. However, this model does not directly support the processing of multiple related data, and the processing performance does not reflect the advantages of cloud computing. To enhance the capability of workflow applications in material data processing, we defined a programming model for material cloud applications that supports multiple different Map and Reduce functions running concurrently based on hybrid share-memory BSP called MaMR. An optimized data sharing strategy to supply the shared data to the different Map and Reduce stages was also designed. We added a new merge phase to MapReduce that can efficiently merge data from the map and reduce modules. Experiments showed that the model and framework present effective performance improvements compared to previous work.

  8. Constructing a strategy map for banking institutions with key performance indicators of the balanced scorecard.

    Science.gov (United States)

    Wu, Hung-Yi

    2012-08-01

    This study presents a structural evaluation methodology to link key performance indicators (KPIs) into a strategy map of the balanced scorecard (BSC) for banking institutions. Corresponding with the four BSC perspectives (finance, customer, internal business process, and learning and growth), the most important evaluation indicators of banking performance are synthesized from the relevant literature and screened by a committee of experts. The Decision Making Trial and Evaluation Laboratory (DEMATEL) method, a multiple criteria analysis tool, is then employed to determine the causal relationships between the KPIs, to identify the critical central and influential factors, and to establish a visualized strategy map with logical links to improve banking performance. An empirical application is provided as an example. According to the expert evaluations, the three most essential KPIs for banking performance are customer satisfaction, sales performance, and customer retention rate. The DEMATEL results demonstrate a clear road map to assist management in prioritizing the performance indicators and in focusing attention on the strategy-related activities of the crucial indicators. According to the constructed strategy map, management could better invest limited resources in the areas that need improvement most. Although these strategy maps of the BSC are not universal, the research results show that the presented approach is an objective and feasible way to construct strategy maps more justifiably. The proposed framework can be applicable to institutions in other industries as well. Copyright © 2011 Elsevier Ltd. All rights reserved.

  9. A network application for modeling a centrifugal compressor performance map

    Science.gov (United States)

    Nikiforov, A.; Popova, D.; Soldatova, K.

    2017-08-01

    The approximation of aerodynamic performance of a centrifugal compressor stage and vaneless diffuser by neural networks is presented. Advantages, difficulties and specific features of the method are described. An example of a neural network and its structure is shown. The performances in terms of efficiency, pressure ratio and work coefficient of 39 model stages within the range of flow coefficient from 0.01 to 0.08 were modeled with mean squared error 1.5 %. In addition, the loss and friction coefficients of vaneless diffusers of relative widths 0.014-0.10 are modeled with mean squared error 2.45 %.

  10. Factors Affecting Students' Performance and Practice on Map ...

    African Journals Online (AJOL)

    The percentage is used to show that the level of the performance and achievement of the students. The findings suggest that possible intervention to help the students score high academic achievement should focus on teachers' training, enabling students to work hard persevere to succeed, identifying effective study ...

  11. Mapping the Developmental Constraints on Working Memory Span Performance

    Science.gov (United States)

    Bayliss, Donna M.; Jarrold, Christopher; Baddeley, Alan D.; Gunn, Deborah M.; Leigh, Eleanor

    2004-01-01

    This study investigated the constraints underlying developmental improvements in complex working memory span performance among 120 children of between 6 and 10 years of age. Independent measures of processing efficiency, storage capacity, rehearsal speed, and basic speed of processing were assessed to determine their contribution to age-related…

  12. Improved diagnosis of the transition to JAK2 (V⁶¹⁷F homozygosity: the key feature for predicting the evolution of myeloproliferative neoplasms.

    Directory of Open Access Journals (Sweden)

    Mariana Selena Gonzalez

    Full Text Available Most cases of BCR-ABL1-negative myeloproliferative neoplasms (MPNs, essential thrombocythemia, polycythemia vera and primary myelofibrosis are associated with JAK2 (V617F mutations. The outcomes of these cases are critically influenced by the transition from JAK2 (V617F heterozygosity to homozygosity. Therefore, a technique providing an unbiased assessment of the critical allele burden, 50% JAK2 (V617F, is highly desirable. In this study, we present an approach to assess the JAK2 (V617F burden from genomic DNA (gDNA and complementary DNA (cDNA using one-plus-one template references for allele-specific quantitative-real-time-PCR (qPCR. Plasmidic gDNA and cDNA constructs encompassing one PCR template for JAK2 (V617F spaced from one template for JAK2(Wild Type were constructed by multiple fusion PCR amplifications. Repeated assessments of the 50% JAK2(V617F burden within the dynamic range of serial dilutions of gDNA and cDNA constructs resulted in 52.53 ± 4.2% and 51.46 ± 4.21%, respectively. The mutation-positive cutoff was estimated to be 3.65% (mean +2 standard deviation using 20 samples from a healthy population. This qPCR approach was compared with the qualitative ARMS-PCR technique and with two standard methods based on qPCR, and highly significant correlations were obtained in all cases. qPCR assays were performed on paired gDNA/cDNA samples from 20 MPN patients, and the JAK2 (V617F expression showed a significant correlation with the allele burden. Our data demonstrate that the qPCR method using one-plus-one template references provides an improved assessment of the clinically relevant transition of JAK2 (V617F from heterozygosity to homozygosity.

  13. Mapping the developmental constraints on working memory span performance.

    Science.gov (United States)

    Bayliss, Donna M; Jarrold, Christopher; Baddeley, Alan D; Gunn, Deborah M; Leigh, Eleanor

    2005-07-01

    This study investigated the constraints underlying developmental improvements in complex working memory span performance among 120 children of between 6 and 10 years of age. Independent measures of processing efficiency, storage capacity, rehearsal speed, and basic speed of processing were assessed to determine their contribution to age-related variance in complex span. Results showed that developmental improvements in complex span were driven by 2 age-related but separable factors: 1 associated with general speed of processing and 1 associated with storage ability. In addition, there was an age-related contribution shared between working memory, processing speed, and storage ability that was important for higher level cognition. These results pose a challenge for models of complex span performance that emphasize the importance of processing speed alone.

  14. Mapping the Conjugate Gradient Algorithm onto High Performance Heterogeneous Computers

    Science.gov (United States)

    2014-05-01

    Solution of sparse indefinite systems of linear equations. Society for Industrial and Applied Mathematis 12(4), 617 –629. Parker, M. ( 2009 ). Taking advantage...44 vii 11 LIST OF SYMBOLS, ABBREVIATIONS, AND NOMENCLATURE API Application Programming Interface ASIC Application Specific Integrated Circuit...FPGA designer, 1 16 2 thus, final implementations were nearly always performed using fixed-point or integer arithmetic (Parker 2009 ). With the recent

  15. Volume perfusion CT imaging of cerebral vasospasm: diagnostic performance of different perfusion maps

    Energy Technology Data Exchange (ETDEWEB)

    Othman, Ahmed E. [RWTH Aachen University, Department of Diagnostic and Interventional Neuroradiology, Aachen (Germany); Eberhard Karls University Tuebingen, University Hospital Tuebingen, Department for Diagnostic and Interventional Radiology, Tuebingen (Germany); Afat, Saif; Nikoubashman, Omid; Mueller, Marguerite; Wiesmann, Martin; Brockmann, Carolin [RWTH Aachen University, Department of Diagnostic and Interventional Neuroradiology, Aachen (Germany); Schubert, Gerrit Alexander [RWTH Aachen University, Department of Neurosurgery, Aachen (Germany); Bier, Georg [Eberhard Karls University Tuebingen, University Hospital Tuebingen, Department for Diagnostic and Interventional Neuroradiology, Tuebingen (Germany); Brockmann, Marc A. [RWTH Aachen University, Department of Diagnostic and Interventional Neuroradiology, Aachen (Germany); University Hospital Mainz, Department of Neuroradiology, Mainz (Germany)

    2016-08-15

    In this study, we aimed to evaluate the diagnostic performance of different volume perfusion CT (VPCT) maps regarding the detection of cerebral vasospasm compared to angiographic findings. Forty-one datasets of 26 patients (57.5 ± 10.8 years, 18 F) with subarachnoid hemorrhage and suspected cerebral vasospasm, who underwent VPCT and angiography within 6 h, were included. Two neuroradiologists independently evaluated the presence and severity of vasospasm on perfusion maps on a 3-point Likert scale (0 - no vasospasm, 1 - vasospasm affecting <50 %, 2 - vasospasm affecting >50 % of vascular territory). A third neuroradiologist independently assessed angiography for the presence and severity of vasospasm on a 3-point Likert scale (0 - no vasospasm, 1 - vasospasm affecting < 50 %, 2 - vasospasm affecting > 50 % of vessel diameter). Perfusion maps of cerebral blood volume (CBV), cerebral blood flow (CBF), mean transit time (MTT), and time to drain (TTD) were evaluated regarding diagnostic accuracy for cerebral vasospasm with angiography as reference standard. Correlation analysis of vasospasm severity on perfusion maps and angiographic images was performed. Furthermore, inter-reader agreement was assessed regarding findings on perfusion maps. Diagnostic accuracy for TTD and MTT was significantly higher than for all other perfusion maps (TTD, AUC = 0.832; MTT, AUC = 0.791; p < 0.001). TTD revealed higher sensitivity than MTT (p = 0.007). The severity of vasospasm on TTD maps showed significantly higher correlation levels with angiography than all other perfusion maps (p ≤ 0.048). Inter-reader agreement was (almost) perfect for all perfusion maps (kappa ≥ 0.927). The results of this study indicate that TTD maps have the highest sensitivity for the detection of cerebral vasospasm and highest correlation with angiography regarding the severity of vasospasm. (orig.)

  16. Using Mind Maps to Improve Medical Student Performance in a Pharmacology Course at Kunming Medical University.

    Science.gov (United States)

    Ying, Guo; Jianping, Xie; Haiyun, Luo; Xia, Li; Jianyu, Yang; Qun, Xuan; Jianyun, Yu

    2017-07-01

    To determine whether students using mind maps would improve their performance in a final examination at the end of lecture-based pharmacology course. Aquasi-experimental study. Kunming Medical University, from September 2014 to January 2015. One hundred and twenty-two (122) third year undergraduate medical students, starting a 48-hour lecturebased pharmacology course, volunteered to use mind maps as one of their study strategies (intervention group), while the remaining 100 students in the class continued to use their usual study strategies (control group) over the duration of the course. The performance of both groups in the final course examination was compared. Students in the intervention group also completed a questionnaire on the usefulness of mind maps during the course and in preparation for the final examination. The students' performance of intervention group was superior to performance of the control group in all parts of a multi-modal final examination. For the multiple choice questions and comprehensive scores, average marks of 45.97 ±7.22 and 68.07 ±12.77, respectively were acquired by the control group, and 51.77 ±4.95 (pcontrol group, and were all significantly higher at 8.00 (4.00) (p=0.024), 10.00 (2.00) (pmind maps helped them to prepare more efficiently for the final exam; 90.91% believed that mind maps helped them to better understand all of pharmacology. Ninety-one percent also thought that mind maps would help them to better understand other disciplines, and 86.36% students would like the lecturers to utilize mind mapping as an alternative to conventional teaching formats, such as the use of Power Point. The addition of mind maps to students' study of pharmacology at Kunming Medical University improved their performance in all aspects of a multi-modal final examination.

  17. Effects of Different Forms of Concept-Map Representation on Nursing Students’ Critical Thinking Performances

    Directory of Open Access Journals (Sweden)

    Chin-Yuan Lai

    2015-06-01

    Full Text Available Representation is important for problem solving. This study examined the effects of different forms of concept maps on nursing students’ performances of conceptualizing psychiatric patients’ problems. A quasi-experimental research design was adopted to investigate the effects. The participants were two classes of fourth-year students who were enrolled in a psychiatric nursing course in a nursing college. One class with 48 students served as the experimental group, and used web-based concepts map to represent patients’ problem. The other class with 50 students served as the control group, and used the traditional hierarchical concept mapping method. The results indicated that the concept maps drawn by the experimental group showed more nursing problem, supporting evidence, and relationships between nursing problems than those drawn by the control group. The web-based concept maps helped expand students’ thinking and promoted their causality reasoning. Different concept-map representation tools affected the process of students’ problem solving. The experimental learning activities promoted students’ understanding of concepts and ways of psychiatric patients’ care taking. To understand the effects of other types of concept maps, future research may guide students in using different forms of concept maps throughout the stages of nursing process.

  18. Novel Graphical Analyses of Runs of Homozygosity among Species and Livestock Breeds

    Directory of Open Access Journals (Sweden)

    Laura Iacolina

    2016-01-01

    Full Text Available Runs of homozygosity (ROH, uninterrupted stretches of homozygous genotypes resulting from parents transmitting identical haplotypes to their offspring, have emerged as informative genome-wide estimates of autozygosity (inbreeding. We used genomic profiles based on 698 K single nucleotide polymorphisms (SNPs from nine breeds of domestic cattle (Bos taurus and the European bison (Bison bonasus to investigate how ROH distributions can be compared within and among species. We focused on two length classes: 0.5–15 Mb to investigate ancient events and >15 Mb to address recent events (approximately three generations. For each length class, we chose a few chromosomes with a high number of ROH, calculated the percentage of times a SNP appeared in a ROH, and plotted the results. We selected areas with distinct patterns including regions where (1 all groups revealed an increase or decrease of ROH, (2 bison differed from cattle, (3 one cattle breed or groups of breeds differed (e.g., dairy versus meat cattle. Examination of these regions in the cattle genome showed genes potentially important for natural and human-induced selection, concerning, for example, meat and milk quality, metabolism, growth, and immune function. The comparative methodology presented here permits visual identification of regions of interest for selection, breeding programs, and conservation.

  19. The Relationship between Runs of Homozygosity and Inbreeding in Jersey Cattle under Selection.

    Directory of Open Access Journals (Sweden)

    Eui-Soo Kim

    Full Text Available Inbreeding is often an inevitable outcome of strong directional artificial selection but on average it reduces population fitness with increased frequency of recessive deleterious alleles. Runs of homozygosity (ROH representing genomic autozygosity that occur from mating between selected and genomically related individuals may be able to reveal the regions affecting fitness. To examine the influence of genomic autozygosity on fitness, we used a genome-wide association test to evaluate potential negative correlations between ROH and daughter pregnancy rate (DPR or somatic cell score (SCS in US Jersey cattle. In addition, relationships between changes of local ROH and inbreeding coefficients (F were assessed to locate genomic regions with increased inbreeding. Despite finding some decreases in fertility associated with incremental increases in F, most emerging local ROH were not significantly associated with DPR or SCS. Furthermore, the analyses of ROH could be approximated with the most frequent haplotype(s, including the associations of ROH and F or traits. The analysis of the most frequent haplotype revealed that associations of ROH and fertility could be accounted for by the additive genetic effect on the trait. Thus, we suggest that a change of autozygosity is more likely to demonstrate footprints of selected haplotypes for production rather than highlight the possible increased local autozygosity of a recessive detrimental allele resulting from the mating between closely related animals in Jersey cattle.

  20. Sardinians genetic background explained by runs of homozygosity and genomic regions under positive selection.

    Directory of Open Access Journals (Sweden)

    Cornelia Di Gaetano

    Full Text Available The peculiar position of Sardinia in the Mediterranean sea has rendered its population an interesting biogeographical isolate. The aim of this study was to investigate the genetic population structure, as well as to estimate Runs of Homozygosity and regions under positive selection, using about 1.2 million single nucleotide polymorphisms genotyped in 1077 Sardinian individuals. Using four different methods--fixation index, inflation factor, principal component analysis and ancestry estimation--we were able to highlight, as expected for a genetic isolate, the high internal homogeneity of the island. Sardinians showed a higher percentage of genome covered by RoHs>0.5 Mb (F(RoH%0.5 when compared to peninsular Italians, with the only exception of the area surrounding Alghero. We furthermore identified 9 genomic regions showing signs of positive selection and, we re-captured many previously inferred signals. Other regions harbor novel candidate genes for positive selection, like TMEM252, or regions containing long non coding RNA. With the present study we confirmed the high genetic homogeneity of Sardinia that may be explained by the shared ancestry combined with the action of evolutionary forces.

  1. The Performance Analysis of AN Indoor Mobile Mapping System with Rgb-D Sensor

    Science.gov (United States)

    Tsai, G. J.; Chiang, K. W.; Chu, C. H.; Chen, Y. L.; El-Sheimy, N.; Habib, A.

    2015-08-01

    Over the years, Mobile Mapping Systems (MMSs) have been widely applied to urban mapping, path management and monitoring and cyber city, etc. The key concept of mobile mapping is based on positioning technology and photogrammetry. In order to achieve the integration, multi-sensor integrated mapping technology has clearly established. In recent years, the robotic technology has been rapidly developed. The other mapping technology that is on the basis of low-cost sensor has generally used in robotic system, it is known as the Simultaneous Localization and Mapping (SLAM). The objective of this study is developed a prototype of indoor MMS for mobile mapping applications, especially to reduce the costs and enhance the efficiency of data collection and validation of direct georeferenced (DG) performance. The proposed indoor MMS is composed of a tactical grade Inertial Measurement Unit (IMU), the Kinect RGB-D sensor and light detection, ranging (LIDAR) and robot. In summary, this paper designs the payload for indoor MMS to generate the floor plan. In first session, it concentrates on comparing the different positioning algorithms in the indoor environment. Next, the indoor plans are generated by two sensors, Kinect RGB-D sensor LIDAR on robot. Moreover, the generated floor plan will compare with the known plan for both validation and verification.

  2. THE PERFORMANCE ANALYSIS OF AN INDOOR MOBILE MAPPING SYSTEM WITH RGB-D SENSOR

    Directory of Open Access Journals (Sweden)

    G. J. Tsai

    2015-08-01

    Full Text Available Over the years, Mobile Mapping Systems (MMSs have been widely applied to urban mapping, path management and monitoring and cyber city, etc. The key concept of mobile mapping is based on positioning technology and photogrammetry. In order to achieve the integration, multi-sensor integrated mapping technology has clearly established. In recent years, the robotic technology has been rapidly developed. The other mapping technology that is on the basis of low-cost sensor has generally used in robotic system, it is known as the Simultaneous Localization and Mapping (SLAM. The objective of this study is developed a prototype of indoor MMS for mobile mapping applications, especially to reduce the costs and enhance the efficiency of data collection and validation of direct georeferenced (DG performance. The proposed indoor MMS is composed of a tactical grade Inertial Measurement Unit (IMU, the Kinect RGB-D sensor and light detection, ranging (LIDAR and robot. In summary, this paper designs the payload for indoor MMS to generate the floor plan. In first session, it concentrates on comparing the different positioning algorithms in the indoor environment. Next, the indoor plans are generated by two sensors, Kinect RGB-D sensor LIDAR on robot. Moreover, the generated floor plan will compare with the known plan for both validation and verification.

  3. Capability Assessment and Performance Metrics for the Titan Multispectral Mapping Lidar

    Directory of Open Access Journals (Sweden)

    Juan Carlos Fernandez-Diaz

    2016-11-01

    Full Text Available In this paper we present a description of a new multispectral airborne mapping light detection and ranging (lidar along with performance results obtained from two years of data collection and test campaigns. The Titan multiwave lidar is manufactured by Teledyne Optech Inc. (Toronto, ON, Canada and emits laser pulses in the 1550, 1064 and 532 nm wavelengths simultaneously through a single oscillating mirror scanner at pulse repetition frequencies (PRF that range from 50 to 300 kHz per wavelength (max combined PRF of 900 kHz. The Titan system can perform simultaneous mapping in terrestrial and very shallow water environments and its multispectral capability enables new applications, such as the production of false color active imagery derived from the lidar return intensities and the automated classification of target and land covers. Field tests and mapping projects performed over the past two years demonstrate capabilities to classify five land covers in urban environments with an accuracy of 90%, map bathymetry under more than 15 m of water, and map thick vegetation canopies at sub-meter vertical resolutions. In addition to its multispectral and performance characteristics, the Titan system is designed with several redundancies and diversity schemes that have proven to be beneficial for both operations and the improvement of data quality.

  4. High-Performance Signal Detection for Adverse Drug Events using MapReduce Paradigm.

    Science.gov (United States)

    Fan, Kai; Sun, Xingzhi; Tao, Ying; Xu, Linhao; Wang, Chen; Mao, Xianling; Peng, Bo; Pan, Yue

    2010-11-13

    Post-marketing pharmacovigilance is important for public health, as many Adverse Drug Events (ADEs) are unknown when those drugs were approved for marketing. However, due to the large number of reported drugs and drug combinations, detecting ADE signals by mining these reports is becoming a challenging task in terms of computational complexity. Recently, a parallel programming model, MapReduce has been introduced by Google to support large-scale data intensive applications. In this study, we proposed a MapReduce-based algorithm, for common ADE detection approach, Proportional Reporting Ratio (PRR), and tested it in mining spontaneous ADE reports from FDA. The purpose is to investigate the possibility of using MapReduce principle to speed up biomedical data mining tasks using this pharmacovigilance case as one specific example. The results demonstrated that MapReduce programming model could improve the performance of common signal detection algorithm for pharmacovigilance in a distributed computation environment at approximately liner speedup rates.

  5. No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study

    Science.gov (United States)

    Bjelland, Douglas W.; Howrigan, Daniel P.; Abdellaoui, Abdel; Breen, Gerome; Borglum, Anders; Cichon, Sven; Degenhardt, Franziska; Forstner, Andreas J.; Genovese, Giulio; Heilmann-Heimbach, Stefanie; Hoffman, Per; Maier, Wolfgang; Mattheisen, Manuel; Morris, Derek; Mowry, Bryan; Müller-Mhysok, Betram; Neale, Benjamin; Nenadic, Igor; Nöthen, Markus M.; O’Dushlaine, Colm; Rietschel, Marcella; Ruderfer, Douglas M.; Rujescu, Dan; Schulze, Thomas G.; Simonson, Matthew A.; Stahl, Eli; Strohmaier, Jana; Sullivan, Patrick F.; Keller, Matthew C.

    2016-01-01

    It is well known that inbreeding increases the risk of recessive monogenic diseases, but it is less certain whether it contributes to the etiology of complex diseases such as schizophrenia. One way to estimate the effects of inbreeding is to examine the association between disease diagnosis and genome-wide autozygosity estimated using runs of homozygosity (ROH) in genome-wide single nucleotide polymorphism arrays. Using data for schizophrenia from the Psychiatric Genomics Consortium (n = 21,868), Keller et al. (2012) estimated that the odds of developing schizophrenia increased by approximately 17% for every additional percent of the genome that is autozygous (β = 16.1, CI(β) = [6.93, 25.7], Z = 3.44, p = 0.0006). Here we describe replication results from 22 independent schizophrenia case-control datasets from the Psychiatric Genomics Consortium (n = 39,830). Using the same ROH calling thresholds and procedures as Keller et al. (2012), we were unable to replicate the significant association between ROH burden and schizophrenia in the independent PGC phase II data, although the effect was in the predicted direction, and the combined (original + replication) dataset yielded an attenuated but significant relationship between Froh and schizophrenia (β = 4.86,CI(β) = [0.90,8.83],Z = 2.40,p = 0.02). Since Keller et al. (2012), several studies reported inconsistent association of ROH burden with complex traits, particularly in case-control data. These conflicting results might suggest that the effects of autozygosity are confounded by various factors, such as socioeconomic status, education, urbanicity, and religiosity, which may be associated with both real inbreeding and the outcome measures of interest. PMID:27792727

  6. Scaffolding EFL Oral Performance through Story Maps and Podcasts and Students’ Attitudes toward it

    Directory of Open Access Journals (Sweden)

    Mohammed Pazhouhesh

    2014-11-01

    Full Text Available The present study sought to explore the impact of story maps and audio podcasts as scaffolds on oral proficiency of Iranian EFL learners. The quasi-experimental study was launched with 36 EFL undergraduates in three groups by adopting a counterbalanced 3  3 Latin squared design. All participants were indiscriminately, but in a specified order, exposed to the three treatment conditions of story retelling, story retelling plus story map, and story retelling plus podcast, and post-tested sequentially. The Latin square analysis of the oral assessment scale showed statistically meaningful differences under the treatment conditions for the groups. The post-hoc test also showed overachievements of the participants under the treatment conditions of story retelling plus story map and story retelling plus podcasts. The performance under podcast condition was significantly better than performances under the story map and short story conditions. The post-experiment opinion survey showed the learners’ preferences for and positive attitudes towards podcast and story map as scaffolds in developing EFL oral proficiency. The participants welcomed integration of the scaffolds into EFL speaking courses.

  7. Transparency about multidimensional activities and performance: What can U-map and U-multirank contribute?

    NARCIS (Netherlands)

    Westerheijden, Donald F.; Rosa, Maria Joao; Amaral, Alberto

    2014-01-01

    Two new, user-driven and web-based transparency tools for higher education are presented: U-Map, a classification of higher education institutions according to their actual activities, and U-Multirank, a multidimensional ranking of higher education institutions’ and study fields’ performances. The

  8. Viewing or Visualising Which Concept Map Strategy Works Best on Problem-Solving Performance?

    Science.gov (United States)

    Lee, Youngmin; Nelson, David W.

    2005-01-01

    The purpose of this study was to investigate the effects of two types of maps (generative vs. completed) and the amount of prior knowledge (high vs. low) on well-structured and ill-structured problem-solving performance. Forty-four undergraduates who were registered in an introductory instructional technology course participated in the study.…

  9. Designs of Concept Maps and Their Impacts on Readers' Performance in Memory and Reasoning while Reading

    Science.gov (United States)

    Tzeng, Jeng-Yi

    2010-01-01

    From the perspective of the Fuzzy Trace Theory, this study investigated the impacts of concept maps with two strategic orientations (comprehensive and thematic representations) on readers' performance of cognitive operations (such as perception, verbatim memory, gist reasoning and syntheses) while the readers were reading two history articles that…

  10. What Happens Inside a Fuel Cell? Developing an Experimental Functional Map of Fuel Cell Performance

    KAUST Repository

    Brett, Daniel J. L.

    2010-08-20

    Fuel cell performance is determined by the complex interplay of mass transport, energy transfer and electrochemical processes. The convolution of these processes leads to spatial heterogeneity in the way that fuel cells perform, particularly due to reactant consumption, water management and the design of fluid-flow plates. It is therefore unlikely that any bulk measurement made on a fuel cell will accurately represent performance at all parts of the cell. The ability to make spatially resolved measurements in a fuel cell provides one of the most useful ways in which to monitor and optimise performance. This Minireview explores a range of in situ techniques being used to study fuel cells and describes the use of novel experimental techniques that the authors have used to develop an \\'experimental functional map\\' of fuel cell performance. These techniques include the mapping of current density, electrochemical impedance, electrolyte conductivity, contact resistance and CO poisoning distribution within working PEFCs, as well as mapping the flow of reactant in gas channels using laser Doppler anemometry (LDA). For the high-temperature solid oxide fuel cell (SOFC), temperature mapping, reference electrode placement and the use of Raman spectroscopy are described along with methods to map the microstructural features of electrodes. The combination of these techniques, applied across a range of fuel cell operating conditions, allows a unique picture of the internal workings of fuel cells to be obtained and have been used to validate both numerical and analytical models. © 2010 Wiley-VCH Verlag GmbH& Co. KGaA, Weinheim.

  11. Preliminary Evaluation of MapReduce for High-Performance Climate Data Analysis

    Science.gov (United States)

    Duffy, Daniel Q.; Schnase, John L.; Thompson, John H.; Freeman, Shawn M.; Clune, Thomas L.

    2012-01-01

    MapReduce is an approach to high-performance analytics that may be useful to data intensive problems in climate research. It offers an analysis paradigm that uses clusters of computers and combines distributed storage of large data sets with parallel computation. We are particularly interested in the potential of MapReduce to speed up basic operations common to a wide range of analyses. In order to evaluate this potential, we are prototyping a series of canonical MapReduce operations over a test suite of observational and climate simulation datasets. Our initial focus has been on averaging operations over arbitrary spatial and temporal extents within Modern Era Retrospective- Analysis for Research and Applications (MERRA) data. Preliminary results suggest this approach can improve efficiencies within data intensive analytic workflows.

  12. Transfer map approach to an optical effects of energy degraders on the performance of fragment separators

    International Nuclear Information System (INIS)

    Erdelyi, B.; Bandura, L.; Nolen, J.

    2009-01-01

    A second order analytical and an arbitrary order numerical procedure is developed for the computation of transfer maps of energy degraders. The incorporation of the wedges into the optics of fragment separators for next-generation exotic beam facilities, their optical effects, and the optimization of their performance is studied in detail. It is shown how to place and shape the degraders in the system such that aberrations are minimized and resolving powers are maximized

  13. Process mapping as a framework for performance improvement in emergency general surgery.

    Science.gov (United States)

    DeGirolamo, Kristin; D'Souza, Karan; Hall, William; Joos, Emilie; Garraway, Naisan; Sing, Chad Kim; McLaughlin, Patrick; Hameed, Morad

    2018-02-01

    Emergency general surgery conditions are often thought of as being too acute for the development of standardized approaches to quality improvement. However, process mapping, a concept that has been applied extensively in manufacturing quality improvement, is now being used in health care. The objective of this study was to create process maps for small bowel obstruction in an effort to identify potential areas for quality improvement. We used the American College of Surgeons Emergency General Surgery Quality Improvement Program pilot database to identify patients who received nonoperative or operative management of small bowel obstruction between March 2015 and March 2016. This database, patient charts and electronic health records were used to create process maps from the time of presentation to discharge. Eighty-eight patients with small bowel obstruction (33 operative; 55 nonoperative) were identified. Patients who received surgery had a complication rate of 32%. The processes of care from the time of presentation to the time of follow-up were highly elaborate and variable in terms of duration; however, the sequences of care were found to be consistent. We used data visualization strategies to identify bottlenecks in care, and they showed substantial variability in terms of operating room access. Variability in the operative care of small bowel obstruction is high and represents an important improvement opportunity in general surgery. Process mapping can identify common themes, even in acute care, and suggest specific performance improvement measures.

  14. A novel multispectral glacier mapping method and its performance in Greenland

    Science.gov (United States)

    Citterio, M.; Fausto, R. S.; Ahlstrom, A. P.; Andersen, S. B.

    2014-12-01

    Multispectral land surface classification methods are widely used for mapping glacier outlines. Significant post-classification manual editing is typically required, and mapping glacier outlines over larger regions remains a rather labour intensive task. In this contribution we introduce a novel method for mapping glacier outlines from multispectral satellite imagery, requiring only minor manual editing.Over the last decade GLIMS (Global Land Ice Measurements from Space) improved the availability of glacier outlines, and in 2012 the Randolph Glacier Inventory (RGI) attained global coverage by compiling existing and new data sources in the wake of the Fifth Assessment Report of the Intergovernmental Panel on Climate Change (IPCC AR5). With the launch of Landsat 8 in 2013 and the upcoming ESA (European Space Agency) Sentinel 2 missions, the availability of multispectral imagery may grow faster than our ability to process it into timely and reliable glacier outline products. Improved automatic classification methods would enable a full exploitation of these new data sources.We outline the theoretical basis of the proposed classification algorithm, provide a step by step walk-through from raw imagery to finished ice cover grids and vector glacier outlines, and evaluate the performance of the new method in mapping the outlines of glaciers, ice caps and the Greenland Ice Sheet from Landsat 8 OLI imagery. The classification output is compared against manually digitized ice margin positions, the RGI vectors, and the PROMICE (Programme for Monitoring of the Greenland Ice Sheet) aerophotogrammetric map of Greenland ice masses over a sector of the Disko Island surge cluster in West Greenland, the Qassimiut ice sheet lobe in South Greenland, and the A.P. Olsen ice cap in NE Greenland.

  15. Performance Analysis of the Microsoft Kinect Sensor for 2D Simultaneous Localization and Mapping (SLAM Techniques

    Directory of Open Access Journals (Sweden)

    Kamarulzaman Kamarudin

    2014-12-01

    Full Text Available This paper presents a performance analysis of two open-source, laser scanner-based Simultaneous Localization and Mapping (SLAM techniques (i.e., Gmapping and Hector SLAM using a Microsoft Kinect to replace the laser sensor. Furthermore, the paper proposes a new system integration approach whereby a Linux virtual machine is used to run the open source SLAM algorithms. The experiments were conducted in two different environments; a small room with no features and a typical office corridor with desks and chairs. Using the data logged from real-time experiments, each SLAM technique was simulated and tested with different parameter settings. The results show that the system is able to achieve real time SLAM operation. The system implementation offers a simple and reliable way to compare the performance of Windows-based SLAM algorithm with the algorithms typically implemented in a Robot Operating System (ROS. The results also indicate that certain modifications to the default laser scanner-based parameters are able to improve the map accuracy. However, the limited field of view and range of Kinect’s depth sensor often causes the map to be inaccurate, especially in featureless areas, therefore the Kinect sensor is not a direct replacement for a laser scanner, but rather offers a feasible alternative for 2D SLAM tasks.

  16. How do task characteristics affect learning and performance? The roles of variably mapped and dynamic tasks.

    Science.gov (United States)

    Macnamara, Brooke N; Frank, David J

    2018-05-01

    For well over a century, scientists have investigated individual differences in performance. The majority of studies have focused on either differences in practice, or differences in cognitive resources. However, the predictive ability of either practice or cognitive resources varies considerably across tasks. We are the first to examine task characteristics' impact on learning and performance in a complex task while controlling for other task characteristics. In 2 experiments we test key theoretical task characteristic thought to moderate the relationship between practice, cognitive resources, and performance. We devised a task where each of several key task characteristics can be manipulated independently. Participants played 5 rounds of a game similar to the popular tower defense videogame Plants vs. Zombies where both cognitive load and game characteristics were manipulated. In Experiment 1, participants either played a consistently mapped version-the stimuli and the associated meaning of their properties were constant across the 5 rounds-or played a variably mapped version-the stimuli and the associated meaning of their properties changed every few minutes. In Experiment 2, participants either played a static version-that is, turn taking with no time pressure-or played a dynamic version-that is, the stimuli moved regardless of participants' response rates. In Experiment 1, participants' accuracy and efficiency were substantially hindered in the variably mapped conditions. In Experiment 2, learning and performance accuracy were hindered in the dynamic conditions, especially when under cognitive load. Our results suggest that task characteristics impact the relative importance of cognitive resources and practice on predicting learning and performance. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  17. Performance of T2 Maps in the Detection of Prostate Cancer.

    Science.gov (United States)

    Chatterjee, Aritrick; Devaraj, Ajit; Mathew, Melvy; Szasz, Teodora; Antic, Tatjana; Karczmar, Gregory S; Oto, Aytekin

    2018-05-03

    This study compares the performance of T2 maps in the detection of prostate cancer (PCa) in comparison to T2-weighted (T2W) magnetic resonance images. The prospective study was institutional review board approved. Consenting patients (n = 45) with histologic confirmed PCa underwent preoperative 3-T magnetic resonance imaging with or without endorectal coil. Two radiologists, working independently, marked regions of interests (ROIs) on PCa lesions separately on T2W images and T2 maps. Each ROI was assigned a score of 1-5 based on the confidence in accurately detecting cancer, with 5 being the highest confidence. Subsequently, the histologically confirmed PCa lesions (n = 112) on whole-mount sections were matched with ROIs to calculate sensitivity, positive predictive value (PPV), and radiologist confidence score. Quantitative T2 values of PCa and benign tissue ROIs were measured. Sensitivity and confidence score for PCa detection were similar for T2W images (51%, 4.5 ± 0.8) and T2 maps (52%, 4.5 ± 0.6). However, PPV was significantly higher (P = .001) for T2 maps (88%) compared to T2W (72%) images. The use of endorectal coils nominally improved sensitivity (T2W: 55 vs 47%, T2 map: 54% vs 48%) compared to the use of no endorectal coils, but not the PPV and the confidence score. Quantitative T2 values for PCa (105 ± 28 milliseconds) were significantly (P = 9.3 × 10 -14 ) lower than benign peripheral zone tissue (211 ± 71 milliseconds), with moderate significant correlation with Gleason score (ρ = -0.284). Our study shows that review of T2 maps by radiologists has similar sensitivity but higher PPV compared to T2W images. Additional quantitative information obtained from T2 maps is helpful in differentiating cancer from normal prostate tissue and determining its aggressiveness. Copyright © 2018 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.

  18. Improvements in Off Design Aeroengine Performance Prediction Using Analytic Compressor Map Interpolation

    Science.gov (United States)

    Mist'e, Gianluigi Alberto; Benini, Ernesto

    2012-06-01

    Compressor map interpolation is usually performed through the introduction of auxiliary coordinates (β). In this paper, a new analytical bivariate β function definition to be used in compressor map interpolation is studied. The function has user-defined parameters that must be adjusted to properly fit to a single map. The analytical nature of β allows for rapid calculations of the interpolation error estimation, which can be used as a quantitative measure of interpolation accuracy and also as a valid tool to compare traditional β function interpolation with new approaches (artificial neural networks, genetic algorithms, etc.). The quality of the method is analyzed by comparing the error output to the one of a well-known state-of-the-art methodology. This comparison is carried out for two different types of compressor and, in both cases, the error output using the method presented in this paper is found to be consistently lower. Moreover, an optimization routine able to locally minimize the interpolation error by shape variation of the β function is implemented. Further optimization introducing other important criteria is discussed.

  19. a Performance Comparison of Feature Detectors for Planetary Rover Mapping and Localization

    Science.gov (United States)

    Wan, W.; Peng, M.; Xing, Y.; Wang, Y.; Liu, Z.; Di, K.; Teng, B.; Mao, X.; Zhao, Q.; Xin, X.; Jia, M.

    2017-07-01

    Feature detection and matching are key techniques in computer vision and robotics, and have been successfully implemented in many fields. So far there is no performance comparison of feature detectors and matching methods for planetary mapping and rover localization using rover stereo images. In this research, we present a comprehensive evaluation and comparison of six feature detectors, including Moravec, Förstner, Harris, FAST, SIFT and SURF, aiming for optimal implementation of feature-based matching in planetary surface environment. To facilitate quantitative analysis, a series of evaluation criteria, including distribution evenness of matched points, coverage of detected points, and feature matching accuracy, are developed in the research. In order to perform exhaustive evaluation, stereo images, simulated under different baseline, pitch angle, and interval of adjacent rover locations, are taken as experimental data source. The comparison results show that SIFT offers the best overall performance, especially it is less sensitive to changes of image taken at adjacent locations.

  20. Neural signatures of Trail Making Test performance: Evidence from lesion-mapping and neuroimaging studies.

    Science.gov (United States)

    Varjacic, Andreja; Mantini, Dante; Demeyere, Nele; Gillebert, Celine R

    2018-03-27

    The Trail Making Test (TMT) is an extensively used neuropsychological instrument for the assessment of set-switching ability across a wide range of neurological conditions. However, the exact nature of the cognitive processes and associated brain regions contributing to the performance on the TMT remains unclear. In this review, we first introduce the TMT by discussing its administration and scoring approaches. We then examine converging evidence and divergent findings concerning the brain regions related to TMT performance, as identified by lesion-symptom mapping studies conducted in brain-injured patients and functional magnetic resonance imaging studies conducted in healthy participants. After addressing factors that may account for the heterogeneity in the brain regions reported by these studies, we identify future research endeavours that may permit disentangling the different processes contributing to TMT performance and relating them to specific brain circuits. Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.

  1. A PERFORMANCE COMPARISON OF FEATURE DETECTORS FOR PLANETARY ROVER MAPPING AND LOCALIZATION

    Directory of Open Access Journals (Sweden)

    W. Wan

    2017-07-01

    Full Text Available Feature detection and matching are key techniques in computer vision and robotics, and have been successfully implemented in many fields. So far there is no performance comparison of feature detectors and matching methods for planetary mapping and rover localization using rover stereo images. In this research, we present a comprehensive evaluation and comparison of six feature detectors, including Moravec, Förstner, Harris, FAST, SIFT and SURF, aiming for optimal implementation of feature-based matching in planetary surface environment. To facilitate quantitative analysis, a series of evaluation criteria, including distribution evenness of matched points, coverage of detected points, and feature matching accuracy, are developed in the research. In order to perform exhaustive evaluation, stereo images, simulated under different baseline, pitch angle, and interval of adjacent rover locations, are taken as experimental data source. The comparison results show that SIFT offers the best overall performance, especially it is less sensitive to changes of image taken at adjacent locations.

  2. High sibling correlation on methylphenidate response but no association with DAT1-10R homozygosity in Dutch sibpairs with ADHD

    NARCIS (Netherlands)

    van der Meulen, Emma M; Bakker, Steven C; Pauls, David L; Oteman, Nicole; Kruitwagen, Cas L J J; Pearson, Peter L; Sinke, Richard J; Buitelaar, Jan K

    2005-01-01

    BACKGROUND: A minority of patients with attention-deficit hyperactivity disorder (ADHD) do not respond favorably to methylphenidate. This has been partially associated with homozygosity for the Dopamine transporter (DAT1) 10-repeat allele and the presence of one or two Dopamine D4 receptor (DRD4)

  3. High sibling correlation on methylphenidate response but no association with DAT1-10R homozygosity in Dutch sibpairs with ADHD.

    NARCIS (Netherlands)

    Meulen, E.M. van der; Bakker, S.C.; Pauls, D.L.; Oteman, N.; Kruitwagen, C.L.J.J.; Pearson, P.L.; Sinke, R.J.; Buitelaar, J.K.

    2005-01-01

    BACKGROUND: A minority of patients with attention-deficit hyperactivity disorder (ADHD) do not respond favorably to methylphenidate. This has been partially associated with homozygosity for the Dopamine transporter (DAT1) 10-repeat allele and the presence of one or two Dopamine D4 receptor (DRD4)

  4. Performance Comparison of OpenMP, MPI, and MapReduce in Practical Problems

    Directory of Open Access Journals (Sweden)

    Sol Ji Kang

    2015-01-01

    Full Text Available With problem size and complexity increasing, several parallel and distributed programming models and frameworks have been developed to efficiently handle such problems. This paper briefly reviews the parallel computing models and describes three widely recognized parallel programming frameworks: OpenMP, MPI, and MapReduce. OpenMP is the de facto standard for parallel programming on shared memory systems. MPI is the de facto industry standard for distributed memory systems. MapReduce framework has become the de facto standard for large scale data-intensive applications. Qualitative pros and cons of each framework are known, but quantitative performance indexes help get a good picture of which framework to use for the applications. As benchmark problems to compare those frameworks, two problems are chosen: all-pairs-shortest-path problem and data join problem. This paper presents the parallel programs for the problems implemented on the three frameworks, respectively. It shows the experiment results on a cluster of computers. It also discusses which is the right tool for the jobs by analyzing the characteristics and performance of the paradigms.

  5. THE PERFORMANCE ANALYSIS OF A UAV BASED MOBILE MAPPING SYSTEM PLATFORM

    Directory of Open Access Journals (Sweden)

    M. L. Tsai

    2013-08-01

    Full Text Available To facilitate applications such as environment detection or disaster monitoring, the development of rapid low cost systems for collecting near real-time spatial information is very critical. Rapid spatial information collection has become an emerging trend for remote sensing and mapping applications. This study develops a Direct Georeferencing (DG based fixed-wing Unmanned Aerial Vehicle (UAV photogrammetric platform where an Inertial Navigation System (INS/Global Positioning System (GPS integrated Positioning and Orientation System (POS system is implemented to provide the DG capability of the platform. The performance verification indicates that the proposed platform can capture aerial images successfully. A flight test is performed to verify the positioning accuracy in DG mode without using Ground Control Points (GCP. The preliminary results illustrate that horizontal DG positioning accuracies in the x and y axes are around 5 m with 300 m flight height. The positioning accuracy in the z axis is less than 10 m. Such accuracy is good for near real-time disaster relief. The DG ready function of proposed platform guarantees mapping and positioning capability even in GCP free environments, which is very important for rapid urgent response for disaster relief. Generally speaking, the data processing time for the DG module, including POS solution generalization, interpolation, Exterior Orientation Parameters (EOP generation, and feature point measurements, is less than one hour.

  6. The Performance Analysis of a Uav Based Mobile Mapping System Platform

    Science.gov (United States)

    Tsai, M. L.; Chiang, K. W.; Lo, C. F.; Ch, C. H.

    2013-08-01

    To facilitate applications such as environment detection or disaster monitoring, the development of rapid low cost systems for collecting near real-time spatial information is very critical. Rapid spatial information collection has become an emerging trend for remote sensing and mapping applications. This study develops a Direct Georeferencing (DG) based fixed-wing Unmanned Aerial Vehicle (UAV) photogrammetric platform where an Inertial Navigation System (INS)/Global Positioning System (GPS) integrated Positioning and Orientation System (POS) system is implemented to provide the DG capability of the platform. The performance verification indicates that the proposed platform can capture aerial images successfully. A flight test is performed to verify the positioning accuracy in DG mode without using Ground Control Points (GCP). The preliminary results illustrate that horizontal DG positioning accuracies in the x and y axes are around 5 m with 300 m flight height. The positioning accuracy in the z axis is less than 10 m. Such accuracy is good for near real-time disaster relief. The DG ready function of proposed platform guarantees mapping and positioning capability even in GCP free environments, which is very important for rapid urgent response for disaster relief. Generally speaking, the data processing time for the DG module, including POS solution generalization, interpolation, Exterior Orientation Parameters (EOP) generation, and feature point measurements, is less than one hour.

  7. Stirling Convertor Performance Mapping Test Results for Future Radioisotope Power Systems

    Science.gov (United States)

    Qiu, Songgang; Peterson, Allen A.; Faultersack, Franklyn D.; Redinger, Darin L.; Augenblick, John E.

    2004-02-01

    Long-life radioisotope-fueled generators based on free-piston Stirling convertors are an energy-conversion solution for future space applications. The high efficiency of Stirling machines makes them more attractive than the thermoelectric generators currently used in space. Stirling Technology Company (STC) has been performance-testing its Stirling generators to provide data for potential system integration contractors. This paper describes the most recent test results from the STC RemoteGen™ 55 W-class Stirling generators (RG-55). Comparisons are made between the new data and previous Stirling thermodynamic simulation models. Performance-mapping tests are presented including variations in: internal charge pressure, cold end temperature, hot end temperature, alternator temperature, input power, and variation of control voltage.

  8. Performance of Multilevel Coding Schemes with Different Decoding Methods and Mapping Strategies in Mobile Fading Channels

    Institute of Scientific and Technical Information of China (English)

    YUAN Dongfeng; WANG Chengxiang; YAO Qi; CAO Zhigang

    2001-01-01

    Based on "capacity rule", the perfor-mance of multilevel coding (MLC) schemes with dif-ferent set partitioning strategies and decoding meth-ods in AWGN and Rayleigh fading channels is investi-gated, in which BCH codes are chosen as componentcodes and 8ASK modulation is used. Numerical re-sults indicate that MLC scheme with UP strategy canobtain optimal performance in AWGN channels andBP is the best mapping strategy for Rayleigh fadingchannels. BP strategy is of good robustness in bothkinds of channels to realize an optimum MLC system.Multistage decoding (MSD) is a sub-optimal decodingmethod of MLC for both channels. For Ungerboeckpartitioning (UP) and mixed partitioning (MP) strat-egy, MSD is strongly recommended to use for MLCsystem, while for BP strategy, PDL is suggested to useas a simple decoding method compared with MSD.

  9. Hadoop-GIS: A High Performance Spatial Data Warehousing System over MapReduce.

    Science.gov (United States)

    Aji, Ablimit; Wang, Fusheng; Vo, Hoang; Lee, Rubao; Liu, Qiaoling; Zhang, Xiaodong; Saltz, Joel

    2013-08-01

    Support of high performance queries on large volumes of spatial data becomes increasingly important in many application domains, including geospatial problems in numerous fields, location based services, and emerging scientific applications that are increasingly data- and compute-intensive. The emergence of massive scale spatial data is due to the proliferation of cost effective and ubiquitous positioning technologies, development of high resolution imaging technologies, and contribution from a large number of community users. There are two major challenges for managing and querying massive spatial data to support spatial queries: the explosion of spatial data, and the high computational complexity of spatial queries. In this paper, we present Hadoop-GIS - a scalable and high performance spatial data warehousing system for running large scale spatial queries on Hadoop. Hadoop-GIS supports multiple types of spatial queries on MapReduce through spatial partitioning, customizable spatial query engine RESQUE, implicit parallel spatial query execution on MapReduce, and effective methods for amending query results through handling boundary objects. Hadoop-GIS utilizes global partition indexing and customizable on demand local spatial indexing to achieve efficient query processing. Hadoop-GIS is integrated into Hive to support declarative spatial queries with an integrated architecture. Our experiments have demonstrated the high efficiency of Hadoop-GIS on query response and high scalability to run on commodity clusters. Our comparative experiments have showed that performance of Hadoop-GIS is on par with parallel SDBMS and outperforms SDBMS for compute-intensive queries. Hadoop-GIS is available as a set of library for processing spatial queries, and as an integrated software package in Hive.

  10. A computational approach for functional mapping of quantitative trait loci that regulate thermal performance curves.

    Directory of Open Access Journals (Sweden)

    John Stephen Yap

    2007-06-01

    Full Text Available Whether and how thermal reaction norm is under genetic control is fundamental to understand the mechanistic basis of adaptation to novel thermal environments. However, the genetic study of thermal reaction norm is difficult because it is often expressed as a continuous function or curve. Here we derive a statistical model for dissecting thermal performance curves into individual quantitative trait loci (QTL with the aid of a genetic linkage map. The model is constructed within the maximum likelihood context and implemented with the EM algorithm. It integrates the biological principle of responses to temperature into a framework for genetic mapping through rigorous mathematical functions established to describe the pattern and shape of thermal reaction norms. The biological advantages of the model lie in the decomposition of the genetic causes for thermal reaction norm into its biologically interpretable modes, such as hotter-colder, faster-slower and generalist-specialist, as well as the formulation of a series of hypotheses at the interface between genetic actions/interactions and temperature-dependent sensitivity. The model is also meritorious in statistics because the precision of parameter estimation and power of QTLdetection can be increased by modeling the mean-covariance structure with a small set of parameters. The results from simulation studies suggest that the model displays favorable statistical properties and can be robust in practical genetic applications. The model provides a conceptual platform for testing many ecologically relevant hypotheses regarding organismic adaptation within the Eco-Devo paradigm.

  11. Improving soft FEC performance for higher-order modulations via optimized bit channel mappings.

    Science.gov (United States)

    Häger, Christian; Amat, Alexandre Graell I; Brännström, Fredrik; Alvarado, Alex; Agrell, Erik

    2014-06-16

    Soft forward error correction with higher-order modulations is often implemented in practice via the pragmatic bit-interleaved coded modulation paradigm, where a single binary code is mapped to a nonbinary modulation. In this paper, we study the optimization of the mapping of the coded bits to the modulation bits for a polarization-multiplexed fiber-optical system without optical inline dispersion compensation. Our focus is on protograph-based low-density parity-check (LDPC) codes which allow for an efficient hardware implementation, suitable for high-speed optical communications. The optimization is applied to the AR4JA protograph family, and further extended to protograph-based spatially coupled LDPC codes assuming a windowed decoder. Full field simulations via the split-step Fourier method are used to verify the analysis. The results show performance gains of up to 0.25 dB, which translate into a possible extension of the transmission reach by roughly up to 8%, without significantly increasing the system complexity.

  12. Performance analysis of a compact and low-cost mapping-grade mobile laser scanning system

    Science.gov (United States)

    Julge, Kalev; Vajakas, Toivo; Ellmann, Artu

    2017-10-01

    The performance of a low-cost, self-contained, compact, and easy to deploy mapping-grade mobile laser scanning (MLS) system, which is composed of a light detection and ranging sensor Velodyne VLP-16 and a dual antenna global navigation satellite system/inertial navigation system SBG Systems Ellipse-D, is analyzed. The field tests were carried out in car-mounted and backpack modes for surveying road engineering structures (such as roads, parking lots, underpasses, and tunnels) and coastal erosion zones, respectively. The impact of applied calculation principles on trajectory postprocessing, direct georeferencing, and the theoretical accuracy of the system is analyzed. A calibration method, based on Bound Optimization BY Quadratic Approximation, for finding the boresight angles of an MLS system is proposed. The resulting MLS point clouds are compared with high-accuracy static terrestrial laser scanning data and survey-grade MLS data from a commercially manufactured MLS system. The vertical, horizontal, and relative accuracy are assessed-the root-mean-square error (RMSE) values were determined to be 8, 15, and 3 cm, respectively. Thus, the achieved mapping-grade accuracy demonstrates that this relatively compact and inexpensive self-assembled MLS can be successfully used for surveying the geometry and deformations of terrain, buildings, road, and other engineering structures.

  13. PERFORMANCE IMPROVEMENT OF IDMA SCHEME USING CHAOTIC MAP INTERLEAVERS FOR FUTURE RADIO COMMUNICATION

    Directory of Open Access Journals (Sweden)

    Aasheesh Shukla

    2017-06-01

    Full Text Available In this paper, chaos based interleavers are proposed for the performance improvement of Interleave Division Multiple Access (IDMA henceforth for future radio communication (FRC requirements. ‘IDMA’ can be mean as the modified case of direct sequence code division multiple access (DS-CDMA with the same spreading sequences and user specific interleavers for distinguishing the users in multi-user environment. In IDMA systems, the roles of interleavers are pre-eminent and an efficient interleaver contributes in optimizing the system performance. Random interleaver is the popular and basic taxonomy in IDMA. The performance of chaos based interleavers is compared to random interleaver. Simulation results authenticate the performance of chaos based IDMA. Further the proposed chaotic map-interleavers have the less computational complexity and efficient in bandwidth compared to the existing prevailing interleaver algorithms in the domain. The IDMA system model uses a BPSK modulation and repetition coder with a code rate of ½. The system is simulated in MATLAB and results show the BER superiority of chaotic interleaver based IDMA without the need of extra storage resources and less computational complexity.

  14. Sustainable-value stream mapping to evaluate sustainability performance: case study in an Indonesian furniture company

    Directory of Open Access Journals (Sweden)

    Hartini Sri

    2018-01-01

    Full Text Available Lean manufacturing tools do not consider environmental and societal benefits. The conventional value stream mapping (VSM methodology examines the economics of a manufacturing line, most of which are in regards to time (cycle time, lead time, change-out time, etc.. Incorporating the capability to capture environmental and societal performance visually through VSMs will increase its usefulness as a tool that can be used to assess manufacturing operations from a sustainability perspective. A number of studies have addressed the extension of VSM to incorporate additional criteria. A vast majority of these efforts have focused on adding energy-related metrics to VSMs, while several other studies refer to ‘sustainable’ VSM by including environmental performance in conventional VSMs. This research has developed a method for VSM integrated with environment metric and social metric for ensuring sustainable manufacture. The proposed technique is capable of visualizing and evaluating manufacturing process performance from sustainability view point. The capability of proposed technique has been tested by an application study on furniture company. The study provides insights to practitioners to visualize process performance in economic, environment and social metric.

  15. DOES GENDER EQUALITY LEAD TO BETTER-PERFORMING ECONOMIES? A BAYESIAN CAUSAL MAP APPROACH

    Directory of Open Access Journals (Sweden)

    Yelda YÜCEL

    2017-01-01

    Full Text Available This study explores the existence of relationships between gender inequalities –represented by the components of the World Economic Forum (WEF Global Gender Gap Index– and the major macroeconomic indicators. The relationships within gender inequalities in education, the labour market, health and the political arena, and between gender inequalities and gross macroeconomic aggregates were modelled with the Bayesian Causal Map, an effective tool that is used to analyze cause-effect relations and conditional dependencies between variables. A data set of 128 countries during the period 2007–2011 is used. Findings reveal that some inequalities have high levels of interaction with each other. In addition, eradicating gender inequalities is found to be associated with better economic performance, mainly in the form of higher gross domestic product growth, investment, and competitiveness.

  16. Plume Tracker: Interactive mapping of volcanic sulfur dioxide emissions with high-performance radiative transfer modeling

    Science.gov (United States)

    Realmuto, Vincent J.; Berk, Alexander

    2016-11-01

    We describe the development of Plume Tracker, an interactive toolkit for the analysis of multispectral thermal infrared observations of volcanic plumes and clouds. Plume Tracker is the successor to MAP_SO2, and together these flexible and comprehensive tools have enabled investigators to map sulfur dioxide (SO2) emissions from a number of volcanoes with TIR data from a variety of airborne and satellite instruments. Our objective for the development of Plume Tracker was to improve the computational performance of the retrieval procedures while retaining the accuracy of the retrievals. We have achieved a 300 × improvement in the benchmark performance of the retrieval procedures through the introduction of innovative data binning and signal reconstruction strategies, and improved the accuracy of the retrievals with a new method for evaluating the misfit between model and observed radiance spectra. We evaluated the accuracy of Plume Tracker retrievals with case studies based on MODIS and AIRS data acquired over Sarychev Peak Volcano, and ASTER data acquired over Kilauea and Turrialba Volcanoes. In the Sarychev Peak study, the AIRS-based estimate of total SO2 mass was 40% lower than the MODIS-based estimate. This result was consistent with a 45% reduction in the AIRS-based estimate of plume area relative to the corresponding MODIS-based estimate. In addition, we found that our AIRS-based estimate agreed with an independent estimate, based on a competing retrieval technique, within a margin of ± 20%. In the Kilauea study, the ASTER-based concentration estimates from 21 May 2012 were within ± 50% of concurrent ground-level concentration measurements. In the Turrialba study, the ASTER-based concentration estimates on 21 January 2012 were in exact agreement with SO2 concentrations measured at plume altitude on 1 February 2012.

  17. Performance of 3DOSEM and MAP algorithms for reconstructing low count SPECT acquisitions

    Energy Technology Data Exchange (ETDEWEB)

    Grootjans, Willem [Radboud Univ. Medical Center, Nijmegen (Netherlands). Dept. of Radiology and Nuclear Medicine; Leiden Univ. Medical Center (Netherlands). Dept. of Radiology; Meeuwis, Antoi P.W.; Gotthardt, Martin; Visser, Eric P. [Radboud Univ. Medical Center, Nijmegen (Netherlands). Dept. of Radiology and Nuclear Medicine; Slump, Cornelis H. [Univ. Twente, Enschede (Netherlands). MIRA Inst. for Biomedical Technology and Technical Medicine; Geus-Oei, Lioe-Fee de [Radboud Univ. Medical Center, Nijmegen (Netherlands). Dept. of Radiology and Nuclear Medicine; Univ. Twente, Enschede (Netherlands). MIRA Inst. for Biomedical Technology and Technical Medicine; Leiden Univ. Medical Center (Netherlands). Dept. of Radiology

    2016-07-01

    Low count single photon emission computed tomography (SPECT) is becoming more important in view of whole body SPECT and reduction of radiation dose. In this study, we investigated the performance of several 3D ordered subset expectation maximization (3DOSEM) and maximum a posteriori (MAP) algorithms for reconstructing low count SPECT images. Phantom experiments were conducted using the National Electrical Manufacturers Association (NEMA) NU2 image quality (IQ) phantom. The background compartment of the phantom was filled with varying concentrations of pertechnetate and indiumchloride, simulating various clinical imaging conditions. Images were acquired using a hybrid SPECT/CT scanner and reconstructed with 3DOSEM and MAP reconstruction algorithms implemented in Siemens Syngo MI.SPECT (Flash3D) and Hermes Hybrid Recon Oncology (Hyrid Recon 3DOSEM and MAP). Image analysis was performed by calculating the contrast recovery coefficient (CRC),percentage background variability (N%), and contrast-to-noise ratio (CNR), defined as the ratio between CRC and N%. Furthermore, image distortion is characterized by calculating the aspect ratio (AR) of ellipses fitted to the hot spheres. Additionally, the performance of these algorithms to reconstruct clinical images was investigated. Images reconstructed with 3DOSEM algorithms demonstrated superior image quality in terms of contrast and resolution recovery when compared to images reconstructed with filtered-back-projection (FBP), OSEM and 2DOSEM. However, occurrence of correlated noise patterns and image distortions significantly deteriorated the quality of 3DOSEM reconstructed images. The mean AR for the 37, 28, 22, and 17 mm spheres was 1.3, 1.3, 1.6, and 1.7 respectively. The mean N% increase in high and low count Flash3D and Hybrid Recon 3DOSEM from 5.9% and 4.0% to 11.1% and 9.0%, respectively. Similarly, the mean CNR decreased in high and low count Flash3D and Hybrid Recon 3DOSEM from 8.7 and 8.8 to 3.6 and 4

  18. Long contiguous stretches of homozygosity spanning shortly the imprinted loci are associated with intellectual disability, autism and/or epilepsy.

    Science.gov (United States)

    Iourov, Ivan Y; Vorsanova, Svetlana G; Korostelev, Sergei A; Zelenova, Maria A; Yurov, Yuri B

    2015-01-01

    Long contiguous stretches of homozygosity (LCSH) (regions/runs of homozygosity) are repeatedly detected by single-nucleotide polymorphism (SNP) chromosomal microarrays. Providing important clues regarding parental relatedness (consanguinity), uniparental disomy, chromosomal recombination or rearrangements, LCSH are rarely considered as a possible epigenetic cause of neurodevelopmental disorders. Additionally, despite being relevant to imprinting, LCSH at imprinted loci have not been truly addressed in terms of pathogenicity. In this study, we examined LCSH in children with unexplained intellectual disability, autism, congenital malformations and/or epilepsy focusing on chromosomal regions which harbor imprinted disease genes. Out of 267 cases, 14 (5.2 %) were found to have LCSH at imprinted loci associated with a clinical outcome. There were 5 cases of LCSH at 15p11.2, 4 cases of LCSH at 7q31.2, 3 cases of LCSH at 11p15.5, and 2 cases of LCSH at 7q21.3. Apart from a case of LCSH at 7q31.33q32.3 (~4 Mb in size), all causative LCSH were 1-1.5 Mb in size. Clinically, these cases were characterized by a weak resemblance to corresponding imprinting diseases (i.e., Silver-Russell, Beckwith-Wiedemann, and Prader-Willi/Angelman syndromes), exhibiting distinctive intellectual disability, autistic behavior, developmental delay, seizures and/or facial dysmorphisms. Parental consanguinity was detected in 8 cases (3 %), and these cases did not exhibit LCSH at imprinted loci. This study demonstrates that shorter LCSH at chromosomes 7q21.3, 7q31.2, 11p15.5, and 15p11.2 occur with a frequency of about 5 % in the children with intellectual disability, autism, congenital malformations and/or epilepsy. Consequently, this type of epigenetic mutations appears to be the most common one among children with neurodevelopmental diseases. Finally, since LCSH less than 2.5-10 Mb in size are generally ignored in diagnostic SNP microarray studies, one can conclude that an important

  19. Numerical investigation and performance characteristic mapping of an Archimedean screw hydroturbine

    Science.gov (United States)

    Schleicher, W. Chris

    Computational Fluid Dynamics (CFD) is a crucial tool in the design and analysis of hydraulic machinery, especially in the design of a micro hydro turbine. The micro hydro turbine in question is for a low head (less than 60 meters), low volumetric flow rate (0.005 m3/s to 0.5 m 3/s) application with rotation rates varying from 200 RPM to 1500 RPM. The design of the runner geometry is discussed, specifically a non-uniform Archimedean Spiral with an outer diameter of 6 inches and length of 19.5 inches. The transient simulation method, making use of a frame of reference change and a rotating mesh between time-steps, is explained as well as the corresponding boundary conditions. Both simulation methods are compared and are determined to produce similar results. The rotating frame of reference method was determined to be the most suitable method for the mapping of performance characteristic such as required head, torque, power, and efficiency. Results of simulations for a non-uniform Archimedean Spiral are then presented. First, a spectral and temporal convergence study is conducted to make sure that the results are independent of time-step and mesh selection. Performance characteristics of a non-uniform pitched blade turbine are determined for a wide range of volumetric flow rates and rotation rates. The maximum efficiency of the turbine is calculated around 72% for the design of the turbine blade considered in the present study.

  20. Concept mapping improves academic performance in problem solving questions in biochemistry subject.

    Science.gov (United States)

    Baig, Mukhtiar; Tariq, Saba; Rehman, Rehana; Ali, Sobia; Gazzaz, Zohair J

    2016-01-01

    To assess the effectiveness of concept mapping (CM) on the academic performance of medical students' in problem-solving as well as in declarative knowledge questions and their perception regarding CM. The present analytical and questionnaire-based study was carried out at Bahria University Medical and Dental College (BUMDC), Karachi, Pakistan. In this analytical study, students were assessed with problem-solving questions (A-type MCQs), and declarative knowledge questions (short essay questions), and 50% of the questions were from the topics learned by CM. Students also filled a 10-item, 3-point Likert scale questionnaire about their perception regarding the effectiveness of the CM approach, and two open-ended questions were also asked. There was a significant difference in the marks obtained in those problem-solving questions, which were learned by CM as compared to those topics which were taught by the traditional lectures (pacademic performance in problem solving but not in declarative knowledge questions. Students' perception about the effectiveness of CM was overwhelmingly positive.

  1. Mapping performance of the fishery industries innovation: A survey in the North Coast of Java

    Science.gov (United States)

    Yusuf, M.; Legowo, A. M.; Albaarri, A. N.; Darmanto, Y. S.; Agustini, T. W.; Setyastuti, A. I.

    2018-01-01

    This study aimed to put the performance indicators of industry innovation fisheries which would be used as inputs to create innovation strategies in order to win the market competition, especially in USA. Survey and in-depth interviews were conducted on 10 industries with shrimp, tuna and crab commodities representing the fishery industry in Indonesia to USA export destination. The result of mapping performance of innovation indicators of Indonesian Fishery Industry resulted the 10’s strategies alternative to win the market. Based on survey result indicate that “the regulation of catch and/or harvest of cultivation factor” is considered the weakest factor in develop innovation with a score of 3.3, while the international trade factor are considered as the strongest factor in developing innovation development with scores 5,0. Aggressive strategy by strengthening the strength owned by the internal industry was by always looking at the opportunity, so that they could take the opportunity to win the market competition at the right time.

  2. A new framework for performance evaluation system using strategy map: A case study of Islamic Azad University of Semnan

    Directory of Open Access Journals (Sweden)

    Afsaneh Mozaffari

    2013-04-01

    Full Text Available During the past few years, there have been extensive developments on Islamic Azad University, which has led on reduction of managerial flexibility. Therefore, these organizations concentrate on their strategic management via usage of the Balanced Model such as Balanced Score Card (BSC to consider different organizational perspectives and it is important to have good description of organizational strategies and goals. The strategy map is a primary factor to assess the performance in different organizational activities. In this paper, the performance evaluation system of Islamic Azad University of Semnan is designed by the utilization of strategy map as a prominent part of BSC.

  3. An Examination of the Effects of Argument Mapping on Students' Memory and Comprehension Performance

    Science.gov (United States)

    Dwyer, Christopher P.; Hogan, Michael J.; Stewart, Ian

    2013-01-01

    Argument mapping (AM) is a method of visually diagramming arguments to allow for easy comprehension of core statements and relations. A series of three experiments compared argument map reading and construction with hierarchical outlining, text summarisation, and text reading as learning methods by examining subsequent memory and comprehension…

  4. Machine vision-based high-resolution weed mapping and patch-sprayer performance simulation

    NARCIS (Netherlands)

    Tang, L.; Tian, L.F.; Steward, B.L.

    1999-01-01

    An experimental machine vision-based patch-sprayer was developed. This sprayer was primarily designed to do real-time weed density estimation and variable herbicide application rate control. However, the sprayer also had the capability to do high-resolution weed mapping if proper mapping techniques

  5. Supporting Problem-Solving Performance Through the Construction of Knowledge Maps

    Science.gov (United States)

    Lee, Youngmin; Baylor, Amy L.; Nelson, David W.

    2005-01-01

    The purpose of this article is to provide five empirically-derived guidelines for knowledge map construction tools that facilitate problem solving. First, the combinational representation principle proposes that conceptual and corresponding procedural knowledge should be represented together (rather than separately) within the knowledge map.…

  6. Performance Comparison of Reputation Assessment Techniques Based on Self-Organizing Maps in Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Sabrina Sicari

    2017-01-01

    Full Text Available Many solutions based on machine learning techniques have been proposed in literature aimed at detecting and promptly counteracting various kinds of malicious attack (data violation, clone, sybil, neglect, greed, and DoS attacks, which frequently affect Wireless Sensor Networks (WSNs. Besides recognizing the corrupted or violated information, also the attackers should be identified, in order to activate the proper countermeasures for preserving network’s resources and to mitigate their malicious effects. To this end, techniques adopting Self-Organizing Maps (SOM for intrusion detection in WSN were revealed to represent a valuable and effective solution to the problem. In this paper, the mechanism, namely, Good Network (GoNe, which is based on SOM and is able to assess the reliability of the sensor nodes, is compared with another relevant and similar work existing in literature. Extensive performance simulations, in terms of nodes’ classification, attacks’ identification, data accuracy, energy consumption, and signalling overhead, have been carried out in order to demonstrate the better feasibility and efficiency of the proposed solution in WSN field.

  7. Use of geological mapping tools to improve the hydraulic performance of SuDS.

    Science.gov (United States)

    Bockhorn, Britta; Klint, Knud Erik Strøyberg; Jensen, Marina Bergen; Møller, Ingelise

    2015-01-01

    Most cities in Denmark are situated on low permeable clay rich deposits. These sediments are of glacial origin and range among the most heterogeneous, with hydraulic conductivities spanning several orders of magnitude. This heterogeneity has obvious consequences for the sizing of sustainable urban drainage systems (SuDS). We have tested methods to reveal geological heterogeneity at field scale to identify the most suitable sites for the placement of infiltration elements and to minimize their required size. We assessed the geological heterogeneity of a clay till plain in Eastern Jutland, Denmark measuring the shallow subsurface resistivity with a geoelectrical multi-electrode system. To confirm the resistivity data we conducted a spear auger mapping. The exposed sediments ranged from clay tills over sandy clay tills to sandy tills and correspond well to the geoelectrical data. To verify the value of geological information for placement of infiltration elements we carried out a number of infiltration tests on geologically different areas across the field, and we observed infiltration rates two times higher in the sandy till area than in the clay till area, thus demonstrating that the hydraulic performance of SuDS can be increased considerably and oversizing avoided if field geological heterogeneity is revealed before placing SuDS.

  8. elPrep: High-Performance Preparation of Sequence Alignment/Map Files for Variant Calling.

    Directory of Open Access Journals (Sweden)

    Charlotte Herzeel

    Full Text Available elPrep is a high-performance tool for preparing sequence alignment/map files for variant calling in sequencing pipelines. It can be used as a replacement for SAMtools and Picard for preparation steps such as filtering, sorting, marking duplicates, reordering contigs, and so on, while producing identical results. What sets elPrep apart is its software architecture that allows executing preparation pipelines by making only a single pass through the data, no matter how many preparation steps are used in the pipeline. elPrep is designed as a multithreaded application that runs entirely in memory, avoids repeated file I/O, and merges the computation of several preparation steps to significantly speed up the execution time. For example, for a preparation pipeline of five steps on a whole-exome BAM file (NA12878, we reduce the execution time from about 1:40 hours, when using a combination of SAMtools and Picard, to about 15 minutes when using elPrep, while utilising the same server resources, here 48 threads and 23GB of RAM. For the same pipeline on whole-genome data (NA12878, elPrep reduces the runtime from 24 hours to less than 5 hours. As a typical clinical study may contain sequencing data for hundreds of patients, elPrep can remove several hundreds of hours of computing time, and thus substantially reduce analysis time and cost.

  9. Pressure mapping and performance of the compression bandage/garment for venous leg ulcer treatment.

    Science.gov (United States)

    Ghosh, S; Mukhopadhyay, A; Sikka, M; Nagla, K S

    2008-08-01

    A study has been conducted on the commercially available compression bandages as regards their performance with time. Pressure mapping of these bandages has been done using a fabricated pressure-measuring device on a mannequin leg to see the effect on pressure due to creep, fabric friction and angle of bandaging. The results show that the creep behavior, frictional behavior and the angle of bandaging have a significant effect on the pressure profile generated by the bandages during application. The regression analysis shows that the surface friction restricts the slippage in a multilayer system. Also the diameters of the limb and the amount of stretch given to the bandage during application have definite impact on the bandage pressure. In case of compression garments, washing improves the pressure generated but not to the extent of the pressure of a virgin garment. Comparing the two compression materials i.e. bandage and garment, it is found that the presence of higher percentage of elastomeric material and a highly close construction in case of garment provides better holding power and a more homogeneous pressure distribution.

  10. Regular Routes: Deep Mapping a Performative Counterpractice for the Daily Commute 1

    Directory of Open Access Journals (Sweden)

    Laura Bissell

    2015-09-01

    Full Text Available This article offers a textual “deep map” of a series of experimental commutes undertaken in the west of Scotland in 2014. Recent developments in the field of transport studies have reconceived travel time as a far richer cultural experience than in previously utilitarian and economic approaches to the “problem” of commuting. Understanding their own commutes in these terms—as spaces of creativity, productivity and transformation—the authors trace the development of a performative “counterpractice” for their daily journeys between home and work. Deep mapping—as a form of “theory-informed story-telling”—is employed as a productive strategy to document this reimagination of ostensibly quotidian and functional travel. Importantly, this particular stage of the project is not presented as an end-point. Striving to develop an ongoing creative engagement with landscape, the authors continue this exploratory mobile research by connecting to other commuters’ journeys, and proposing a series of “strategies” for reimagining the daily commute; a list of prompts for future action within the routines and spaces of commuting. A range of alternative approaches to commuting are offered here to anyone who regularly travels to and from work to employ or develop as they wish, extending the mapping process to other routes and contexts.

  11. Performance of non-parametric algorithms for spatial mapping of tropical forest structure

    Directory of Open Access Journals (Sweden)

    Liang Xu

    2016-08-01

    Full Text Available Abstract Background Mapping tropical forest structure is a critical requirement for accurate estimation of emissions and removals from land use activities. With the availability of a wide range of remote sensing imagery of vegetation characteristics from space, development of finer resolution and more accurate maps has advanced in recent years. However, the mapping accuracy relies heavily on the quality of input layers, the algorithm chosen, and the size and quality of inventory samples for calibration and validation. Results By using airborne lidar data as the “truth” and focusing on the mean canopy height (MCH as a key structural parameter, we test two commonly-used non-parametric techniques of maximum entropy (ME and random forest (RF for developing maps over a study site in Central Gabon. Results of mapping show that both approaches have improved accuracy with more input layers in mapping canopy height at 100 m (1-ha pixels. The bias-corrected spatial models further improve estimates for small and large trees across the tails of height distributions with a trade-off in increasing overall mean squared error that can be readily compensated by increasing the sample size. Conclusions A significant improvement in tropical forest mapping can be achieved by weighting the number of inventory samples against the choice of image layers and the non-parametric algorithms. Without future satellite observations with better sensitivity to forest biomass, the maps based on existing data will remain slightly biased towards the mean of the distribution and under and over estimating the upper and lower tails of the distribution.

  12. Simulating the Sky as Seen by the Square Kilometer Array using the MIT Array Performance Simulator (MAPS)

    Science.gov (United States)

    Matthews, Lynn D.; Cappallo, R. J.; Doeleman, S. S.; Fish, V. L.; Lonsdale, C. J.; Oberoi, D.; Wayth, R. B.

    2009-05-01

    The Square Kilometer Array (SKA) is a proposed next-generation radio telescope that will operate at frequencies of 0.1-30 GHz and be 50-100 times more sensitive than existing radio arrays. Meeting the performance goals of this instrument will require innovative new hardware and software developments, a variety of which are now under consideration. Key to evaluating the performance characteristics of proposed SKA designs and testing the feasibility of new data calibration and processing algorithms is the ability to carry out realistic simulations of radio wavelength arrays under a variety of observing conditions. The MIT Array Performance Simulator (MAPS) (http://www.haystack.mit.edu/ast/arrays/maps/index.html) is an observations simulation package designed to achieve this goal. MAPS accepts an input source list or sky model and generates a model visibility set for a user-defined "virtual observatory'', incorporating such factors as array geometry, primary beam shape, field-of-view, and time and frequency resolution. Optionally, effects such as thermal noise, out-of-beam sources, variable station beams, and time/location-dependent ionospheric effects can be included. We will showcase current capabilities of MAPS for SKA applications by presenting results from an analysis of the effects of realistic sky backgrounds on the achievable image fidelity and dynamic range of SKA-like arrays comprising large numbers of small-diameter antennas.

  13. Relation of project managers' personality and project performance: An approach based on value stream mapping

    Directory of Open Access Journals (Sweden)

    Maurizio Bevilacqua

    2014-09-01

    Full Text Available Purpose: This work investigates the influence of project managers’ personality on the success of a project in a Multinational Corporation. The methodology proposed for analyzing the project managers’ personality is based on the Myers-Briggs Type Indicator.Design/methodology/approach: Forty projects carried out in 2012 by multinational corporation, concerning new product development (NPD, have been analyzed, comparing the profile of project managers with results obtained in terms of traditional performance indexes (time delay and over-budget of projects and performance indexes usually used in “Lean Production” sector (waste time and type of “wastes”. A detailed analysis of the most important “wastes” during the project development is carried out using the Value Stream Mapping (VSM technique.Findings and Originality/value: Relying on the Myers–Briggs personality instrument, results show that extroverted managers (as opposed to introverted managers carry out projects that show lower delay and lower waste time. Introverted managers often make “Over-processing” and “Defect” types of waste. Moreover, lower delay and over-budget have been shown by perceiving managers.Research limitations: Regarding the limitations of this work it is necessary to highlight that we collected data from project managers in a retrospective way. While we believe that several aspects of our data collection effort helped enhance the accuracy of the results, future research could conduct real-time case study research to get more detailed insights into the proposed relationships and avoid retrospective bias. Moreover we focused on a single respondent, the project manager. This helped us ensure that their interpretations played an important role in product development. But, we cannot examined the opinion of team members that could be different from project managers opinion regarding some questions.Originality/value: This research provides insight useful

  14. Achieving high signal-to-noise performance for a velocity-map imaging experiment

    International Nuclear Information System (INIS)

    Roberts, E.H.; Cavanagh, S.J.; Gibson, S.T.; Lewis, B.R.; Dedman, C.J.; Picker, G.J.

    2005-01-01

    Since the publication of the pioneering paper on velocity-map imaging in 1997, by Eppink and Parker [A.T.J.B. Eppink, D.H. Parker, Rev. Sci. Instrum. 68 (1997) 3477], numerous groups have applied this method in a variety of ways and to various targets. However, despite this interest, little attention has been given to the inherent difficulties and problems associated with this method. In implementing a velocity-map imaging system for photoelectron spectroscopy for the photo-detachment of anion radicals, we have developed a coaxial velocity-map imaging spectrometer. Examined are the advantages and disadvantages of such a system, in particular the sources of noise and the methods used to reduce it

  15. Control Grouped Pedagogical Experiment to Test the Performance of Second-generation Web Maps and the Traditional Maps at the University of Debrecen

    Directory of Open Access Journals (Sweden)

    Dániel Balla

    2015-01-01

    Full Text Available Almost every component of the information society is influenced by elements built on communication technology. Learning also tends to be related to the dynamic usage of computers. Nowadays, a number of applications (online or offline are also available that engage large groups of potential users and simultaneously provide a virtual environment to facilitate learning. This study introduces the self-developed interactive blind map teaching-examining e-learning system of the University of Debrecen. Results of testing the system with a control group are also presented.Both experimental and control groups of students were required to sita test of topographic knowledge following a semester of study. The pass mark for the test was 80%. The experimental group used the new digital environment to study, while the control group prepared for their exam using paper maps in the traditional way. The key research questions addressed by the study were to determine whether exam results obtained by the group using the ‘digital’ method better than those of the control's; and if there were a difference between the exam performances of the two groups, was this statistically significant and, therefore, likely to occur in other similar scenarios?

  16. Use of geological mapping tools to improve the hydraulic performance of SuDS

    DEFF Research Database (Denmark)

    Bockhorn, Britta; Klint, Knud Erik; Jensen, Marina Bergen

    2015-01-01

    measuring the shallow subsurface resistivity with a geoelectrical multi-electrode system. To confirm the resistivity data we conducted a spear auger mapping. The exposed sediments ranged from clay tills over sandy clay tills to sandy tills and correspond well to the geoelectrical data. To verify the value...

  17. Effects of body-mapping-designed clothing on heat stress and running performance in a hot environment.

    Science.gov (United States)

    Jiao, Jiao; Li, Yi; Yao, Lei; Chen, Yajun; Guo, Yueping; Wong, Stephen H S; Ng, Frency S F; Hu, Junyan

    2017-10-01

    To investigate clothing-induced differences in human thermal response and running performance, eight male athletes participated in a repeated-measure study by wearing three sets of clothing (CloA, CloB, and CloC). CloA and CloB were body-mapping-designed with 11% and 7% increased capacity of heat dissipation respectively than CloC, the commonly used running clothing. The experiments were conducted by using steady-state running followed by an all-out performance running in a controlled hot environment. Participants' thermal responses such as core temperature (T c ), mean skin temperature ([Formula: see text]), heat storage (S), and the performance running time were measured. CloA resulted in shorter performance time than CloC (323.1 ± 10.4 s vs. 353.6 ± 13.2 s, p = 0.01), and induced the lowest [Formula: see text], smallest ΔT c , and smallest S in the resting and running phases. This study indicated that clothing made with different heat dissipation capacities affects athlete thermal responses and running performance in a hot environment. Practitioner Summary: A protocol that simulated the real situation in running competitions was used to investigate the effects of body-mapping-designed clothing on athletes' thermal responses and running performance. The findings confirmed the effects of optimised clothing with body-mapping design and advanced fabrics, and ensured the practical advantage of developed clothing on exercise performance.

  18. Diagnostic performance of qualitative shear-wave elastography according to different color map opacities for breast masses.

    Science.gov (United States)

    Kim, Hana; Youk, Ji Hyun; Gweon, Hye Mi; Kim, Jeong-Ah; Son, Eun Ju

    2013-08-01

    To compare the diagnostic performance of qualitative shear-wave elastography (SWE) according to three different color map opacities for breast masses 101 patients aged 21-77 years with 113 breast masses underwent B-mode US and SWE under three different color map opacities (50%, 19% and 100%) before biopsy or surgery. Following SWE features were reviewed: visual pattern classification (pattern 1-4), color homogeneity (Ehomo) and six-point color score of maximum elasticity (Ecol). Combined with B-mode US and SWE, the likelihood of malignancy (LOM) was also scored. The area under the curve (AUC) was obtained by ROC curve analysis to assess the diagnostic performance under each color opacity. A visual color pattern, Ehomo, Ecol and LOM scoring were significantly different between benign and malignant lesions under all color opacities (Pbreast lesion under all color opacities. The difference in color map opacity did not significantly influence diagnostic performance of SWE. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  19. Performance Analysis of Long-Reach Coherent Detection OFDM-PON Downstream Transmission Using m-QAM-Mapped OFDM Signal

    Science.gov (United States)

    Pandey, Gaurav; Goel, Aditya

    2017-12-01

    In this paper, orthogonal frequency division multiplexing (OFDM)-passive optical network (PON) downstream transmission is demonstrated over different lengths of fiber at remote node (RN) for different m-QAM (quadrature amplitude modulation)-mapped OFDM signal (m=4, 16, 32 and 64) transmission from the central office (CO) for different data rates (10, 20 30 and 40 Gbps) using coherent detection at the user end or optical network unit (ONU). Investigation is performed with different number of subcarriers (32, 64, 128, 512 and 1,024), back-to-back optical signal-to-noise ratio (OSNR) along with transmitted and received constellation diagrams for m-QAM-mapped coherent OFDM downstream transmission at different speeds over different transmission distances. Received optical power is calculated for different bit error rates (BERs) at different speeds using m-QAM-mapped coherent detection OFDM downstream transmission. No dispersion compensation is utilized in between the fiber span. Simulation results suggest the different lengths and data rates that can be used for different m-QAM-mapped coherent detection OFDM downstream transmission, and the proposed system may be implemented in next-generation high-speed PONs (NG-PONs).

  20. Failure detection in high-performance clusters and computers using chaotic map computations

    Science.gov (United States)

    Rao, Nageswara S.

    2015-09-01

    A programmable media includes a processing unit capable of independent operation in a machine that is capable of executing 10.sup.18 floating point operations per second. The processing unit is in communication with a memory element and an interconnect that couples computing nodes. The programmable media includes a logical unit configured to execute arithmetic functions, comparative functions, and/or logical functions. The processing unit is configured to detect computing component failures, memory element failures and/or interconnect failures by executing programming threads that generate one or more chaotic map trajectories. The central processing unit or graphical processing unit is configured to detect a computing component failure, memory element failure and/or an interconnect failure through an automated comparison of signal trajectories generated by the chaotic maps.

  1. A Three-Dimensional Foil Bearing Performance Map Applied to Oil-Free Turbomachinery

    Science.gov (United States)

    2009-04-01

    stress brought on by excessive viscous power loss; therefore a map that graphically relates component and system-level parameters (bearing size, applied...Introduction Foil bearings are self-acting, hydrodynamic gas bearings that use air as their working fluid . Their use in rotating systems eliminates the...weight, maintenance requirements, speed, and temperature limitations associated with conventional oil-lubricated rotor supports (i.e., bearings, dampers

  2. An evaluation of the performance of tag SNPs derived from HapMap in a Caucasian population.

    Directory of Open Access Journals (Sweden)

    Alexandre Montpetit

    2006-03-01

    Full Text Available The Haplotype Map (HapMap project recently generated genotype data for more than 1 million single-nucleotide polymorphisms (SNPs in four population samples. The main application of the data is in the selection of tag single-nucleotide polymorphisms (tSNPs to use in association studies. The usefulness of this selection process needs to be verified in populations outside those used for the HapMap project. In addition, it is not known how well the data represent the general population, as only 90-120 chromosomes were used for each population and since the genotyped SNPs were selected so as to have high frequencies. In this study, we analyzed more than 1,000 individuals from Estonia. The population of this northern European country has been influenced by many different waves of migrations from Europe and Russia. We genotyped 1,536 randomly selected SNPs from two 500-kbp ENCODE regions on Chromosome 2. We observed that the tSNPs selected from the CEPH (Centre d'Etude du Polymorphisme Humain from Utah (CEU HapMap samples (derived from US residents with northern and western European ancestry captured most of the variation in the Estonia sample. (Between 90% and 95% of the SNPs with a minor allele frequency of more than 5% have an r2 of at least 0.8 with one of the CEU tSNPs. Using the reverse approach, tags selected from the Estonia sample could almost equally well describe the CEU sample. Finally, we observed that the sample size, the allelic frequency, and the SNP density in the dataset used to select the tags each have important effects on the tagging performance. Overall, our study supports the use of HapMap data in other Caucasian populations, but the SNP density and the bias towards high-frequency SNPs have to be taken into account when designing association studies.

  3. The MAPS-based vertex detector for the STAR experiment: Lessons learned and performance

    Energy Technology Data Exchange (ETDEWEB)

    Contin, Giacomo, E-mail: gcontin@lbl.gov

    2016-09-21

    The PiXeL detector (PXL) of the STAR experiment at RHIC is the first application of the state-of-the-art thin Monolithic Active Pixel Sensors (MAPS) technology in a collider environment. The PXL, together with the Intermediate Silicon Tracker (IST) and the Silicon Strip Detector (SSD), form the Heavy Flavor Tracker (HFT), which has been designed to improve the vertex resolution and extend the STAR measurement capabilities in the heavy flavor domain, providing a clean probe for studying the Quark–Gluon Plasma. The two PXL layers are placed at a radius of 2.8 and 8 cm from the beam line, respectively, and is based on ultra-thin high resolution MAPS sensors. The sensor features 20.7 μm pixel pitch, 185.6 μs readout time and 170 mW/cm{sup 2} power dissipation. The detector is air-cooled, allowing a global material budget of 0.4% radiation length on the innermost layer. A novel mechanical approach to detector insertion allows for fast installation and integration of the pixel sub detector. The HFT took data in Au+Au collisions at 200 GeV during the 2014 RHIC run. Modified during the RHIC shutdown to improve its reliability, material budget, and tracking capabilities, the HFT took data in p+p and p+Au collisions at √s{sub NN}=200 GeV in the 2015 RHIC run. In this paper we present detector specifications, experience from the construction and operations, and lessons learned. We also show preliminary results from 2014 Au+Au data analyses, demonstrating the capabilities of charm reconstruction with the HFT. - Highlights: • First MAPS-based vertex detector in a collider experiment. • Achieved low material budget of 0.39% of radiation length per detector layer. • Track pointing resolution to the primary vertex better than 10⊕24 GeV/p×c μm. • Gain in significance for the topological reconstruction of the D{sup 0}−>K+π decay in STAR. • Observed latch-up induced damage of MAPS sensors.

  4. A Manual for the Performance of Protective Equipment Fit-Mapping

    Science.gov (United States)

    2009-10-01

    Fit Map Derived Accommodation Envelopes Stature Chest Circumference 1 2 3 4 5 A 760-900 1500- 1590 1520-1640 1590 -1710 B 820-960 1500-1620 1520-1640...Right and Left ISO Definition No. N/A CAESAR Name: THELION/BUSTPOINT, RIGHT AND LEFT Description: Most anterior protrusion of the bra cup on women ...Development. pp. 19-59. 17. Robinette, K.M. (1996). Flight suit sizes for women , Armstrong Laboratory, Brooke AFB, MIPR Number 96MM6646. 18

  5. Concomitant homozygosity for the prothrombin gene variant with mild deficiency of antithrombin III in a patient with multiple hepatic infarctions: a case report

    Directory of Open Access Journals (Sweden)

    Macheta M

    2010-04-01

    Full Text Available Abstract Introduction Hereditary causes of visceral thrombosis or thrombosis should be sought among young patients. We present a case of a young man presenting with multiple hepatic infarctions resulting in portal hypertension due to homozygosity of the prothrombin gene mutation not previously described in literature. Case presentation A 42-year-old Caucasian man with a previous history of idiopathic deep vein thrombosis 11 years earlier presented with vague abdominal pains and mildly abnormal liver function tests. An ultrasound and computed tomography scan showed evidence of hepatic infarction and portal hypertension (splenic varices. A thrombophilia screen confirmed a homozygous mutation for the prothrombin gene mutation, with mildly reduced levels of anti-thrombin III (AT III. Subsequent testing of his father and brother revealed heterozygosity for the same gene mutation. Conclusion Hepatic infarction is unusual due to the rich dual arterial and venous blood supply to the liver. In the absence of an arterial or haemodynamic insult causing hepatic infarction, a thrombophilia should be considered. To our knowledge, this is the first reported case of a hepatic infarction due to homozygosity of the prothrombin gene mutation. It is unclear whether homozygotes have a higher risk of thrombosis than heterozygotes. In someone presenting with a first thrombosis with this mutation, the case for life-long anticoagulation is unclear, but it may be necessary to prevent a second and more severe second thrombotic event, as occurred in this case.

  6. Impact of Voltage Mapping to Guide Whether to Perform Ablation of the Posterior Wall in Patients With Persistent Atrial Fibrillation.

    Science.gov (United States)

    Cutler, Michael J; Johnson, Jeremy; Abozguia, Khalid; Rowan, Shane; Lewis, William; Costantini, Otto; Natale, Andrea; Ziv, Ohad

    2016-01-01

    Fibrosis as a substrate for atrial fibrillation (AF) has been shown in numerous preclinical models. Voltage mapping enables in vivo assessment of scar in the left atrium (LA), which can be targeted with catheter ablation. We hypothesized that using the presence or absence of low voltage to guide ablation beyond pulmonary vein antral isolation (PVAI) will improve atrial arrhythmia (AF/AT)-free survival in persistent AF. Single-center retrospective analysis of 2 AF ablation strategies: (1) standard ablation (SA) versus (2) voltage-guided ablation (VGA). PVAI was performed in both groups. With SA, additional lesions beyond PVAI were performed at the discretion of the operator. With VGA, additional lesions to isolate the LA posterior wall were performed if voltage mapping of this region in sinus rhythm showed scar (LA voltage atrial size. Posterior wall ablation was performed in 57% of patient with SA compared to 42% with VGA. VGA ablation increased 1-year AF-/AT-free survival in patients when compared to SA (80% vs. 57%; P = 0.005). In a multivariate analysis, VGA was the only independent predictor of AF-/AT-free survival (hazard ratio of 0.30; P = 0.002). The presence of LA posterior wall scar may be an important ablation target in persistent AF. A prospective randomized trial is needed to confirm these data. © 2015 Wiley Periodicals, Inc.

  7. Performance of Global-Appearance Descriptors in Map Building and Localization Using Omnidirectional Vision

    Directory of Open Access Journals (Sweden)

    Luis Payá

    2014-02-01

    Full Text Available Map building and localization are two crucial abilities that autonomous robots must develop. Vision sensors have become a widespread option to solve these problems. When using this kind of sensors, the robot must extract the necessary information from the scenes to build a representation of the environment where it has to move and to estimate its position and orientation with robustness. The techniques based on the global appearance of the scenes constitute one of the possible approaches to extract this information. They consist in representing each scene using only one descriptor which gathers global information from the scene. These techniques present some advantages comparing to other classical descriptors, based on the extraction of local features. However, it is important a good configuration of the parameters to reach a compromise between computational cost and accuracy. In this paper we make an exhaustive comparison among some global appearance descriptors to solve the mapping and localization problem. With this aim, we make use of several image sets captured in indoor environments under realistic working conditions. The datasets have been collected using an omnidirectional vision sensor mounted on the robot.

  8. Mapping the performance of wood-burning stoves by installations worldwide

    DEFF Research Database (Denmark)

    Luis Teles de Carvalho, Ricardo; Jensen, Ole Michael; Tarelho, Luis A. C.

    2016-01-01

    environmental health risk. Research stressed the need to increase the performance of conventional interplays between users, stoves and buildings. This scientific review aims to characterize the performance and environmental effects of 9 wood-burning stove categories by installations worldwide...

  9. What Happens Inside a Fuel Cell? Developing an Experimental Functional Map of Fuel Cell Performance

    KAUST Repository

    Brett, Daniel J. L.; Kucernak, Anthony R.; Aguiar, Patricia; Atkins, Stephen C.; Brandon, Nigel P.; Clague, Ralph; Cohen, Lesley F.; Hinds, Gareth; Kalyvas, Christos; Offer, Gregory J.; Ladewig, Bradley; Maher, Robert; Marquis, Andrew; Shearing, Paul; Vasileiadis, Nikos; Vesovic, Velisa

    2010-01-01

    Fuel cell performance is determined by the complex interplay of mass transport, energy transfer and electrochemical processes. The convolution of these processes leads to spatial heterogeneity in the way that fuel cells perform, particularly due

  10. Screen media usage, sleep time and academic performance in adolescents: clustering a self-organizing maps analysis.

    Science.gov (United States)

    Peiró-Velert, Carmen; Valencia-Peris, Alexandra; González, Luis M; García-Massó, Xavier; Serra-Añó, Pilar; Devís-Devís, José

    2014-01-01

    Screen media usage, sleep time and socio-demographic features are related to adolescents' academic performance, but interrelations are little explored. This paper describes these interrelations and behavioral profiles clustered in low and high academic performance. A nationally representative sample of 3,095 Spanish adolescents, aged 12 to 18, was surveyed on 15 variables linked to the purpose of the study. A Self-Organizing Maps analysis established non-linear interrelationships among these variables and identified behavior patterns in subsequent cluster analyses. Topological interrelationships established from the 15 emerging maps indicated that boys used more passive videogames and computers for playing than girls, who tended to use mobile phones to communicate with others. Adolescents with the highest academic performance were the youngest. They slept more and spent less time using sedentary screen media when compared to those with the lowest performance, and they also showed topological relationships with higher socioeconomic status adolescents. Cluster 1 grouped boys who spent more than 5.5 hours daily using sedentary screen media. Their academic performance was low and they slept an average of 8 hours daily. Cluster 2 gathered girls with an excellent academic performance, who slept nearly 9 hours per day, and devoted less time daily to sedentary screen media. Academic performance was directly related to sleep time and socioeconomic status, but inversely related to overall sedentary screen media usage. Profiles from the two clusters were strongly differentiated by gender, age, sedentary screen media usage, sleep time and academic achievement. Girls with the highest academic results had a medium socioeconomic status in Cluster 2. Findings may contribute to establishing recommendations about the timing and duration of screen media usage in adolescents and appropriate sleep time needed to successfully meet the demands of school academics and to improve

  11. Screen media usage, sleep time and academic performance in adolescents: clustering a self-organizing maps analysis.

    Directory of Open Access Journals (Sweden)

    Carmen Peiró-Velert

    Full Text Available Screen media usage, sleep time and socio-demographic features are related to adolescents' academic performance, but interrelations are little explored. This paper describes these interrelations and behavioral profiles clustered in low and high academic performance. A nationally representative sample of 3,095 Spanish adolescents, aged 12 to 18, was surveyed on 15 variables linked to the purpose of the study. A Self-Organizing Maps analysis established non-linear interrelationships among these variables and identified behavior patterns in subsequent cluster analyses. Topological interrelationships established from the 15 emerging maps indicated that boys used more passive videogames and computers for playing than girls, who tended to use mobile phones to communicate with others. Adolescents with the highest academic performance were the youngest. They slept more and spent less time using sedentary screen media when compared to those with the lowest performance, and they also showed topological relationships with higher socioeconomic status adolescents. Cluster 1 grouped boys who spent more than 5.5 hours daily using sedentary screen media. Their academic performance was low and they slept an average of 8 hours daily. Cluster 2 gathered girls with an excellent academic performance, who slept nearly 9 hours per day, and devoted less time daily to sedentary screen media. Academic performance was directly related to sleep time and socioeconomic status, but inversely related to overall sedentary screen media usage. Profiles from the two clusters were strongly differentiated by gender, age, sedentary screen media usage, sleep time and academic achievement. Girls with the highest academic results had a medium socioeconomic status in Cluster 2. Findings may contribute to establishing recommendations about the timing and duration of screen media usage in adolescents and appropriate sleep time needed to successfully meet the demands of school academics and

  12. Geometrical Model of Solar Radiation Pressure Based on High-Performing Galileo Clocks - First Geometrical Mapping of the Yarkowsky effect

    Science.gov (United States)

    Svehla, Drazen; Rothacher, Markus; Hugentobler, Urs; Steigenberger, Peter; Ziebart, Marek

    2014-05-01

    Solar radiation pressure is the main source of errors in the precise orbit determination of GNSS satellites. All deficiencies in the modeling of Solar radiation pressure map into estimated terrestrial reference frame parameters as well as into derived gravity field coefficients and altimetry results when LEO orbits are determined using GPS. Here we introduce a new approach to geometrically map radial orbit perturbations of GNSS satellites using highly-performing clocks on board the first Galileo satellites. Only a linear model (time bias and time drift) needs to be removed from the estimated clock parameters and the remaining clock residuals map all radial orbit perturbations along the orbit. With the independent SLR measurements, we show that a Galileo clock is stable enough to map radial orbit perturbations continuously along the orbit with a negative sign in comparison to SLR residuals. Agreement between the SLR residuals and the clock residuals is at the 1 cm RMS for an orbit arc of 24 h. Looking at the clock parameters determined along one orbit revolution over a period of one year, we show that the so-called SLR bias in Galileo and GPS orbits can be explained by the translation of the determined orbit in the orbital plane towards the Sun. This orbit translation is due to thermal re-radiation and not accounting for the Sun elevation in the parameterization of the estimated Solar radiation pressure parameters. SLR ranging to GNSS satellites takes place typically at night, e.g. between 6 pm and 6 am local time when the Sun is in opposition to the satellite. Therefore, SLR observes only one part of the GNSS orbit with a negative radial orbit error that is mapped as an artificial bias in SLR observables. The Galileo clocks clearly show orbit translation for all Sun elevations: the radial orbit error is positive when the Sun is in conjuction (orbit noon) and negative when the Sun is in opposition (orbit midnight). The magnitude of this artificial negative SLR bias

  13. The impact of noisy and misaligned attenuation maps on human-observer performance at lesion detection in SPECT

    Science.gov (United States)

    Wells, R. G.; Gifford, H. C.; Pretorius, P. H.; Famcombe, T. H.; Narayanan, M. V.; King, M. A.

    2002-06-01

    We have demonstrated an improvement due to attenuation correction (AC) at the task of lesion detection in thoracic SPECT images. However, increased noise in the transmission data due to aging sources or very large patients, and misregistration of the emission and transmission maps, can reduce the accuracy of the AC and may result in a loss of lesion detectability. We investigated the impact of noise in and misregistration of transmission data, on the detection of simulated Ga-67 thoracic lesions. Human-observer localization-receiver-operating-characteristic (LROC) methodology was used to assess performance. Both emission and transmission data were simulated using the MCAT computer phantom. Emission data were reconstructed using OSEM incorporating AC and detector resolution compensation. Clinical noise levels were used in the emission data. The transmission-data noise levels ranged from zero (noise-free) to 32 times the measured clinical levels. Transaxial misregistrations of 0.32, 0.63, and 1.27 cm between emission and transmission data were also examined. Three different algorithms were considered for creating the attenuation maps: filtered backprojection (FBP), unbounded maximum-likelihood (ML), and block-iterative transmission AB (BITAB). Results indicate that a 16-fold increase in the noise was required to eliminate the benefit afforded by AC, when using FBP or ML to reconstruct the attenuation maps. When using BITAB, no significant loss in performance was observed for a 32-fold increase in noise. Misregistration errors are also a concern as even small errors here reduce the performance gains of AC.

  14. Diagnostic performance of qualitative shear-wave elastography according to different color map opacities for breast masses

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hana; Youk, Ji Hyun, E-mail: jhyouk@yuhs.ac; Gweon, Hye Mi; Kim, Jeong-Ah; Son, Eun Ju

    2013-08-15

    Purpose: To compare the diagnostic performance of qualitative shear-wave elastography (SWE) according to three different color map opacities for breast masses Materials and methods: 101 patients aged 21–77 years with 113 breast masses underwent B-mode US and SWE under three different color map opacities (50%, 19% and 100%) before biopsy or surgery. Following SWE features were reviewed: visual pattern classification (pattern 1–4), color homogeneity (E{sub homo}) and six-point color score of maximum elasticity (E{sub col}). Combined with B-mode US and SWE, the likelihood of malignancy (LOM) was also scored. The area under the curve (AUC) was obtained by ROC curve analysis to assess the diagnostic performance under each color opacity. Results: A visual color pattern, E{sub homo}, E{sub col} and LOM scoring were significantly different between benign and malignant lesions under all color opacities (P < 0.001). For 50% opacity, AUCs of visual color pattern, E{sub col}, E{sub homo} and LOM scoring were 0.902, 0.951, 0.835 and 0.975. But, for each SWE feature, there was no significant difference in the AUC among three different color opacities. For all color opacities, visual color pattern and E{sub col} showed significantly higher AUC than E{sub homo}. In addition, a combined set of B-mode US and SWE showed significantly higher AUC than SWE alone for color patterns, E{sub homo}, but no significant difference was found in E{sub col}. Conclusion: Qualitative SWE was useful to differentiate benign from malignant breast lesion under all color opacities. The difference in color map opacity did not significantly influence diagnostic performance of SWE.

  15. Diagnostic performance of qualitative shear-wave elastography according to different color map opacities for breast masses

    International Nuclear Information System (INIS)

    Kim, Hana; Youk, Ji Hyun; Gweon, Hye Mi; Kim, Jeong-Ah; Son, Eun Ju

    2013-01-01

    Purpose: To compare the diagnostic performance of qualitative shear-wave elastography (SWE) according to three different color map opacities for breast masses Materials and methods: 101 patients aged 21–77 years with 113 breast masses underwent B-mode US and SWE under three different color map opacities (50%, 19% and 100%) before biopsy or surgery. Following SWE features were reviewed: visual pattern classification (pattern 1–4), color homogeneity (E homo ) and six-point color score of maximum elasticity (E col ). Combined with B-mode US and SWE, the likelihood of malignancy (LOM) was also scored. The area under the curve (AUC) was obtained by ROC curve analysis to assess the diagnostic performance under each color opacity. Results: A visual color pattern, E homo , E col and LOM scoring were significantly different between benign and malignant lesions under all color opacities (P < 0.001). For 50% opacity, AUCs of visual color pattern, E col , E homo and LOM scoring were 0.902, 0.951, 0.835 and 0.975. But, for each SWE feature, there was no significant difference in the AUC among three different color opacities. For all color opacities, visual color pattern and E col showed significantly higher AUC than E homo . In addition, a combined set of B-mode US and SWE showed significantly higher AUC than SWE alone for color patterns, E homo , but no significant difference was found in E col . Conclusion: Qualitative SWE was useful to differentiate benign from malignant breast lesion under all color opacities. The difference in color map opacity did not significantly influence diagnostic performance of SWE

  16. Participatory Maps

    DEFF Research Database (Denmark)

    Salovaara-Moring, Inka

    2016-01-01

    practice. In particular, mapping environmental damage, endangered species, and human-made disasters has become one focal point for environmental knowledge production. This type of digital map has been highlighted as a processual turn in critical cartography, whereas in related computational journalism...... of a geo-visualization within information mapping that enhances embodiment in the experience of the information. InfoAmazonia is defined as a digitally created map-space within which journalistic practice can be seen as dynamic, performative interactions between journalists, ecosystems, space, and species...

  17. Performance of engineering undergraduate students in mathematics: A case study in UniMAP

    Science.gov (United States)

    Saad, Syafawati Ab.; Azziz, Nor Hizamiyani Abdul; Zakaria, Siti Aisyah; Yazid, Nornadia Mohd

    2015-12-01

    The purpose of this paper is to study the trend performance of the first year engineering students at a public university in Mathematics course: Engineering Mathematics I. We analyze how ethnicity factor influenced students' performance in mathematics course over three years period. The performance of the undergraduate students in this study is measured by their cumulative grade point average (CGPA) in the first semester. Analysis of Variance (ANOVA) will be used to test the significance difference between three variables (Malay, Chinese and Indian). Method of simple linear regression (SLR) is used to test the relationship between the performances and to predict the future performance for this course. The findings of the study show that Chinese students perform better than Malay and Indian students.

  18. Mapping Disciplinary Values and Rhetorical Concerns through Language: Writing Instruction in the Performing and Visual Arts

    Science.gov (United States)

    Cox, Anicca

    2015-01-01

    Via interview data focused on instructor practices and values, this study sought to describe some of what performing and visual arts instructors do at the university level to effectively teach disciplinary values through writing. The study's research goals explored how relationships to writing process in visual and performing arts support…

  19. The effect of using digital mind mapping on cognitive achievement and performance level of some basic skills in handball

    Directory of Open Access Journals (Sweden)

    Khaled Thabet Awad

    2016-07-01

    Full Text Available This study aims to identify the effect of using digital mind maps to on the cognitive achievement and the performance level of some basic skills in handball. Research population includes the first-year students at the Faculty of Physical Education in Port Said consisting of 200 students. Research Sample both researchers randomly selected the sample of first year students. The total sample size reaches 180 students with a 90.00%, after excluding failed students, re-registered students, the students of other levels of curriculum, practitioners to previous experiences and irregular students. The total number was 20 students with a percentage of (10.00%. They were divided into: Basic Sample: includes 80 students with a 44.44%. They were divided into two equal groups of 40 students. First Exploratory Sample: includes 60 students from the same research population and from outside the basic sample in order to find Tests Validity of the tests with a 33.33%. Second Exploratory Sample: includes 40 students from the same research population and from outside the basic sample in order to find Tests Reliability of the tests and identify the extent of pilot program appropriateness for the sample under discussion with a 22.22%. The first-year students were selected, according to the study plan, which contains a handball curriculum for the students of this educational level. Statistical Treatments: Both researchers conducted data statistically processes, using a statistical package for Social Sciences, SPSS ver. 20.0, in order to identify: arithmetic mean, standard deviation, median, skewness coefficient, correlation coefficient, discriminant validity coefficient, "t" test per one group, "t" test per two groups. The use of mind maps has a positive effect better than (explanation and model method on the cognitive achievement and the performance level of some basic skills in handball. Active learning techniques, such as the method of digital mind maps in teaching

  20. Use of Self-Organizing Maps for Balanced Scorecard analysis to monitor the performance of dialysis clinic chains.

    Science.gov (United States)

    Cattinelli, Isabella; Bolzoni, Elena; Barbieri, Carlo; Mari, Flavio; Martin-Guerrero, José David; Soria-Olivas, Emilio; Martinez-Martinez, José Maria; Gomez-Sanchis, Juan; Amato, Claudia; Stopper, Andrea; Gatti, Emanuele

    2012-03-01

    The Balanced Scorecard (BSC) is a validated tool to monitor enterprise performances against specific objectives. Through the choice and the evaluation of strategic Key Performance Indicators (KPIs), it provides a measure of the past company's outcome and allows planning future managerial strategies. The Fresenius Medical Care (FME) BSC makes use of 30 KPIs for a continuous quality improvement strategy within its dialysis clinics. Each KPI is monthly associated to a score that summarizes the clinic efficiency for that month. Standard statistical methods are currently used to analyze the BSC data and to give a comprehensive view of the corporate improvements to the top management. We herein propose the Self-Organizing Maps (SOMs) as an innovative approach to extrapolate information from the FME BSC data and to present it in an easy-readable informative form. A SOM is a computational technique that allows projecting high-dimensional datasets to a two-dimensional space (map), thus providing a compressed representation. The SOM unsupervised (self-organizing) training procedure results in a map that preserves similarity relations existing in the original dataset; in this way, the information contained in the high-dimensional space can be more easily visualized and understood. The present work demonstrates the effectiveness of the SOM approach in extracting useful information from the 30-dimensional BSC dataset: indeed, SOMs enabled both to highlight expected relationships between the KPIs and to uncover results not predictable with traditional analyses. Hence we suggest SOMs as a reliable complementary approach to the standard methods for BSC interpretation.

  1. An airborne interferometric SAR system for high-performance 3D mapping

    Science.gov (United States)

    Lange, Martin; Gill, Paul

    2009-05-01

    With a vertical accuracy better than 1 m and collection rates up to 7000 km2/h, airborne interferometric synthetic aperture radars (InSAR) bridge the gap between space borne radar sensors and airborne optical LIDARs. This paper presents the latest generation of X-band InSAR sensors, developed by Intermap TechnologiesTM, which are operated on our four aircrafts. The sensors collect data for the NEXTMap(R) program - a digital elevation model (DEM) with 1 m vertical accuracy for the contiguous U.S., Hawaii, and most of Western Europe. For a successful operation, challenges like reduction of multipath reflections, very high interferometric phase stability, and a precise system calibration had to be mastered. Recent advances in sensor design, comprehensive system automation and diagnostics have increased the sensor reliability to a level where no radar operator is required onboard. Advanced flight planning significantly improved aircraft utilization and acquisition throughput, while reducing operational costs. Highly efficient data acquisition with straight flight lines up to 1200 km is daily routine meanwhile. The collected data pass though our automated processing cluster and finally are edited to our terrain model products. Extensive and rigorous quality control at every step of the workflow are key to maintain stable vertical accuracies of 1 m and horizontal accuracies of 2 m for our 3D maps. The combination of technical and operational advances presented in this paper enabled Intermap to survey two continents, producing 11 million km2 of uniform and accurate 3D terrain data.

  2. T1 mapping cardiovascular magnetic resonance imaging to detect myocarditis—Impact of slice orientation on the diagnostic performance

    Energy Technology Data Exchange (ETDEWEB)

    Bohnen, Sebastian, E-mail: s.bohnen@uke.de [University Medical Center Hamburg-Eppendorf, University Heart Center, General and Interventional Cardiology, Hamburg (Germany); Radunski, Ulf K., E-mail: u.radunski@uke.de [University Medical Center Hamburg-Eppendorf, University Heart Center, General and Interventional Cardiology, Hamburg (Germany); Lund, Gunnar K., E-mail: glund@uke.de [University Medical Center Hamburg-Eppendorf, Department of Diagnostic and Interventional Radiology, Hamburg (Germany); Tahir, Enver, E-mail: e.tahir@uke.de [University Medical Center Hamburg-Eppendorf, Department of Diagnostic and Interventional Radiology, Hamburg (Germany); Avanesov, Maxim, E-mail: m.avanesov@uke.de [University Medical Center Hamburg-Eppendorf, Department of Diagnostic and Interventional Radiology, Hamburg (Germany); Stehning, Christian, E-mail: christian.stehning@philips.com [Philips Research, Hamburg (Germany); Schnackenburg, Bernhard, E-mail: bernhard.schnackenburg@philips.com [Philips Healthcare Germany, Hamburg (Germany); Adam, Gerhard, E-mail: g.adam@uke.de [University Medical Center Hamburg-Eppendorf, Department of Diagnostic and Interventional Radiology, Hamburg (Germany); Blankenberg, Stefan, E-mail: s.blankenberg@uke.de [University Medical Center Hamburg-Eppendorf, University Heart Center, General and Interventional Cardiology, Hamburg (Germany); Muellerleile, Kai, E-mail: kamuellerleile@uke.de [University Medical Center Hamburg-Eppendorf, University Heart Center, General and Interventional Cardiology, Hamburg (Germany)

    2017-01-15

    Background: T1 mapping is a promising diagnostic tool to improve the diagnostic accuracy of cardiovascular magnetic resonance (CMR) in patients with suspected myocarditis. However, there are currently no data on the potential influence of slice orientation on the diagnostic performance of CMR. Thus, we compared the diagnostic performance of global myocardial T1 and extracellular volume (ECV) values to differentiate patients with myocarditis from healthy individuals between different slice orientations. Methods: This study included 48 patients with clinically defined myocarditis and 13 healthy controls who underwent CMR at 1.5 T. A modified Look-Locker inversion-recovery (MOLLI) sequence was used for T1 mapping before and 15 min after administration of 0.075 mmol/kg Gadolinium-BOPTA. T1 mapping was performed on three short and on three long axes slices, respectively. Native T1, post-contrast T1 and extracellular volume (ECV) −BOPTA maps were calculated using a dedicated plug-in written for the OsiriX software and compared between the mean value of three short-axes slices (3SAX), the central short-axis (1SAX), the mean value of three long-axes slices (3LAX), the four-chamber view (4CH), the three-chamber view (3CH) and the two-chamber view (2CH). Results: There were significantly lower native T1 values on 3LAX (1081 ms (1037–1131 ms)) compared to 3SAX (1107 ms (1069–1143 ms), p = 0.0022) in patients with myocarditis, but not in controls (1026 ms (1009–1059 ms) vs. 1039 ms (1023–1055 ms), p = 0.2719). The areas under the curve (AUC) to discriminate between myocarditis and healthy controls by native myocardial T1 were 0.85 (p < 0.0001) on 3SAX, 0.85 (p < 0.0001) on 1SAX, 0.76 (p = 0.0002) on 3LAX, 0.70 (p = 0.0075) on 4CH, 0.72 (p = 0.0020) on 3CH and 0.75 (p = 0.0003) on 2CH. The AUCs for ECV-BOPTA were 0.83 (p < 0.0001) on 3 SAX, 0.82 (p < 0.0001) on 1SAX, 0.77 (p = 0.0005) on 3LAX, 0.71 (p = 0.0079) on 4CH, 0.69 (p = 0.0371) on 3CH and 0.75 (p = 0.0006) on

  3. T1 mapping cardiovascular magnetic resonance imaging to detect myocarditis—Impact of slice orientation on the diagnostic performance

    International Nuclear Information System (INIS)

    Bohnen, Sebastian; Radunski, Ulf K.; Lund, Gunnar K.; Tahir, Enver; Avanesov, Maxim; Stehning, Christian; Schnackenburg, Bernhard; Adam, Gerhard; Blankenberg, Stefan; Muellerleile, Kai

    2017-01-01

    Background: T1 mapping is a promising diagnostic tool to improve the diagnostic accuracy of cardiovascular magnetic resonance (CMR) in patients with suspected myocarditis. However, there are currently no data on the potential influence of slice orientation on the diagnostic performance of CMR. Thus, we compared the diagnostic performance of global myocardial T1 and extracellular volume (ECV) values to differentiate patients with myocarditis from healthy individuals between different slice orientations. Methods: This study included 48 patients with clinically defined myocarditis and 13 healthy controls who underwent CMR at 1.5 T. A modified Look-Locker inversion-recovery (MOLLI) sequence was used for T1 mapping before and 15 min after administration of 0.075 mmol/kg Gadolinium-BOPTA. T1 mapping was performed on three short and on three long axes slices, respectively. Native T1, post-contrast T1 and extracellular volume (ECV) −BOPTA maps were calculated using a dedicated plug-in written for the OsiriX software and compared between the mean value of three short-axes slices (3SAX), the central short-axis (1SAX), the mean value of three long-axes slices (3LAX), the four-chamber view (4CH), the three-chamber view (3CH) and the two-chamber view (2CH). Results: There were significantly lower native T1 values on 3LAX (1081 ms (1037–1131 ms)) compared to 3SAX (1107 ms (1069–1143 ms), p = 0.0022) in patients with myocarditis, but not in controls (1026 ms (1009–1059 ms) vs. 1039 ms (1023–1055 ms), p = 0.2719). The areas under the curve (AUC) to discriminate between myocarditis and healthy controls by native myocardial T1 were 0.85 (p < 0.0001) on 3SAX, 0.85 (p < 0.0001) on 1SAX, 0.76 (p = 0.0002) on 3LAX, 0.70 (p = 0.0075) on 4CH, 0.72 (p = 0.0020) on 3CH and 0.75 (p = 0.0003) on 2CH. The AUCs for ECV-BOPTA were 0.83 (p < 0.0001) on 3 SAX, 0.82 (p < 0.0001) on 1SAX, 0.77 (p = 0.0005) on 3LAX, 0.71 (p = 0.0079) on 4CH, 0.69 (p = 0.0371) on 3CH and 0.75 (p = 0.0006) on

  4. Mapping the Social Side of Pre-Service Teachers: Connecting Closeness, Trust, and Efficacy with Performance

    Science.gov (United States)

    Liou, Yi-Hwa; Daly, Alan J.; Canrinus, Esther T.; Forbes, Cheryl A.; Moolenaar, Nienke M.; Cornelissen, Frank; Van Lare, Michelle; Hsiao, Joyce

    2017-01-01

    This exploratory study foregrounds the important, but often understudied social side of pre-service teacher development and its relation to teaching performance in one university-based teacher preparation program in the US. We examine the extent to which pre-service elementary teachers' social relationships and perceptions of peer trust and…

  5. Mapping the social side of pre-service teachers : connecting closeness, trust, and efficacy with performance

    NARCIS (Netherlands)

    Liou, Yi Hwa; Daly, Alan J.; Canrinus, Esther T.; Forbes, Cheryl A.; Moolenaar, Nienke M.|info:eu-repo/dai/nl/304352802; Cornelissen, Frank; Van Lare, Michelle; Hsiao, Joyce

    2017-01-01

    This exploratory study foregrounds the important, but often understudied social side of pre-service teacher development and its relation to teaching performance in one university-based teacher preparation program in the US. We examine the extent to which pre-service elementary teachers’ social

  6. Functional MRI mapping of visual function and selective attention for performance assessment and presurgical planning using conjunctive visual search.

    Science.gov (United States)

    Parker, Jason G; Zalusky, Eric J; Kirbas, Cemil

    2014-03-01

    Accurate mapping of visual function and selective attention using fMRI is important in the study of human performance as well as in presurgical treatment planning of lesions in or near visual centers of the brain. Conjunctive visual search (CVS) is a useful tool for mapping visual function during fMRI because of its greater activation extent compared with high-capacity parallel search processes. The purpose of this work was to develop and evaluate a CVS that was capable of generating consistent activation in the basic and higher level visual areas of the brain by using a high number of distractors as well as an optimized contrast condition. Images from 10 healthy volunteers were analyzed and brain regions of greatest activation and deactivation were determined using a nonbiased decomposition of the results at the hemisphere, lobe, and gyrus levels. The results were quantified in terms of activation and deactivation extent and mean z-statistic. The proposed CVS was found to generate robust activation of the occipital lobe, as well as regions in the middle frontal gyrus associated with coordinating eye movements and in regions of the insula associated with task-level control and focal attention. As expected, the task demonstrated deactivation patterns commonly implicated in the default-mode network. Further deactivation was noted in the posterior region of the cerebellum, most likely associated with the formation of optimal search strategy. We believe the task will be useful in studies of visual and selective attention in the neuroscience community as well as in mapping visual function in clinical fMRI.

  7. Performance metrics for state-of-the-art airborne magnetic and electromagnetic systems for mapping and detection of unexploded ordnance

    Science.gov (United States)

    Doll, William E.; Bell, David T.; Gamey, T. Jeffrey; Beard, Les P.; Sheehan, Jacob R.; Norton, Jeannemarie

    2010-04-01

    Over the past decade, notable progress has been made in the performance of airborne geophysical systems for mapping and detection of unexploded ordnance in terrestrial and shallow marine environments. For magnetometer systems, the most significant improvements include development of denser magnetometer arrays and vertical gradiometer configurations. In prototype analyses and recent Environmental Security Technology Certification Program (ESTCP) assessments using new production systems the greatest sensitivity has been achieved with a vertical gradiometer configuration, despite model-based survey design results which suggest that dense total-field arrays would be superior. As effective as magnetometer systems have proven to be at many sites, they are inadequate at sites where basalts and other ferrous geologic formations or soils produce anomalies that approach or exceed those of target ordnance items. Additionally, magnetometer systems are ineffective where detection of non-ferrous ordnance items is of primary concern. Recent completion of the Battelle TEM-8 airborne time-domain electromagnetic system represents the culmination of nearly nine years of assessment and development of airborne electromagnetic systems for UXO mapping and detection. A recent ESTCP demonstration of this system in New Mexico showed that it was able to detect 99% of blind-seeded ordnance items, 81mm and larger, and that it could be used to map in detail a bombing target on a basalt flow where previous airborne magnetometer surveys had failed. The probability of detection for the TEM-8 in the blind-seeded study area was better than that reported for a dense-array total-field magnetometer demonstration of the same blind-seeded site, and the TEM-8 system successfully detected these items with less than half as many anomaly picks as the dense-array total-field magnetometer system.

  8. Exome sequencing in schizophrenic patients with high levels of homozygosity identifies novel and extremely rare mutations in the GABA/glutamatergic pathways.

    Directory of Open Access Journals (Sweden)

    Edoardo Giacopuzzi

    Full Text Available Inbreeding is a known risk factor for recessive Mendelian diseases and previous studies have suggested that it could also play a role in complex disorders, such as psychiatric diseases. Recent inbreeding results in the presence of long runs of homozygosity (ROHs along the genome, which are also defined as autozygosity regions. Genetic variants in these regions have two alleles that are identical by descent, thus increasing the odds of bearing rare recessive deleterious mutations due to a homozygous state. A recent study showed a suggestive enrichment of long ROHs in schizophrenic patients, suggesting that recent inbreeding could play a role in the disease. To better understand the impact of autozygosity on schizophrenia risk, we selected, from a cohort of 180 Italian patients, seven subjects with extremely high numbers of large ROHs that were likely due to recent inbreeding and characterized the mutational landscape within their ROHs using Whole Exome Sequencing and, gene set enrichment analysis. We identified a significant overlap (17%; empirical p-value = 0.0171 between genes inside ROHs affected by low frequency functional homozygous variants (107 genes and the group of most promising candidate genes mutated in schizophrenia. Moreover, in four patients, we identified novel and extremely rare damaging mutations in the genes involved in neurodevelopment (MEGF8 and in GABA/glutamatergic synaptic transmission (GAD1, FMN1, ANO2. These results provide insights into the contribution of rare recessive mutations and inbreeding as risk factors for schizophrenia. ROHs that are likely due to recent inbreeding harbor a combination of predisposing low-frequency variants and extremely rare variants that have a high impact on pivotal biological pathways implicated in the disease. In addition, this study confirms that focusing on patients with high levels of homozygosity could be a useful prioritization strategy for discovering new high-impact mutations in

  9. Exome sequencing in schizophrenic patients with high levels of homozygosity identifies novel and extremely rare mutations in the GABA/glutamatergic pathways.

    Science.gov (United States)

    Giacopuzzi, Edoardo; Gennarelli, Massimo; Minelli, Alessandra; Gardella, Rita; Valsecchi, Paolo; Traversa, Michele; Bonvicini, Cristian; Vita, Antonio; Sacchetti, Emilio; Magri, Chiara

    2017-01-01

    Inbreeding is a known risk factor for recessive Mendelian diseases and previous studies have suggested that it could also play a role in complex disorders, such as psychiatric diseases. Recent inbreeding results in the presence of long runs of homozygosity (ROHs) along the genome, which are also defined as autozygosity regions. Genetic variants in these regions have two alleles that are identical by descent, thus increasing the odds of bearing rare recessive deleterious mutations due to a homozygous state. A recent study showed a suggestive enrichment of long ROHs in schizophrenic patients, suggesting that recent inbreeding could play a role in the disease. To better understand the impact of autozygosity on schizophrenia risk, we selected, from a cohort of 180 Italian patients, seven subjects with extremely high numbers of large ROHs that were likely due to recent inbreeding and characterized the mutational landscape within their ROHs using Whole Exome Sequencing and, gene set enrichment analysis. We identified a significant overlap (17%; empirical p-value = 0.0171) between genes inside ROHs affected by low frequency functional homozygous variants (107 genes) and the group of most promising candidate genes mutated in schizophrenia. Moreover, in four patients, we identified novel and extremely rare damaging mutations in the genes involved in neurodevelopment (MEGF8) and in GABA/glutamatergic synaptic transmission (GAD1, FMN1, ANO2). These results provide insights into the contribution of rare recessive mutations and inbreeding as risk factors for schizophrenia. ROHs that are likely due to recent inbreeding harbor a combination of predisposing low-frequency variants and extremely rare variants that have a high impact on pivotal biological pathways implicated in the disease. In addition, this study confirms that focusing on patients with high levels of homozygosity could be a useful prioritization strategy for discovering new high-impact mutations in genetically

  10. The favorable role of homozygosity for killer immunoglobulin-like receptor (KIR A haplotype in patients with advanced-stage classic Hodgkin lymphoma

    Directory of Open Access Journals (Sweden)

    Giorgio La Nasa

    2016-03-01

    Full Text Available Abstract Background Interim positron emission tomography after 2 cycles of ABVD (iPET-2 is a good predictor of outcome in advanced-stage classic Hodgkin lymphoma. So far, there are no other prognostic biomarkers capable of identifying chemotherapy refractory patients with comparable accuracy. Despite the considerable amount of evidence suggesting that antitumor immune surveillance is downregulated in classic Hodgkin lymphoma (cHL, few data exist on the impairment of natural killer cell function and the role of their killer immunoglobulin-like receptors (KIRs. Methods We investigated KIR gene frequencies, KIR haplotypes, and KIR-ligand combinations in a cohort of 135 patients with advanced-stage classic Hodgkin lymphoma and 221 healthy controls. We furthermore evaluated the correlation of KIR genes and KIR haplotypes with the achievement of negative iPET-2. Results In the cohort of patients, the 5-year overall survival and progression-free survival were 93.6 and 79 %, respectively. Homozygosity for KIR A haplotype and the HLA-C1 KIR ligand (KIR-AA/C1C1 was significantly higher in healthy controls (15.7 vs. 4.8 %, p = 0.001. The KIR-AA genotype resulted to have a significant predictive power for achieving iPET-2 negativity (p = 0.039. Conclusions Homozygosity for KIR A haplotype offers protection against classic Hodgkin lymphoma. The association found for the KIR-AA genotype and achievement of negative iPET-2 suggests that KIR-AA could be used in clinical practice to enhance the chemosensitivity predictive power of iPET-2. Our results point to the possibility of adapting treatment strategies based on the combination of KIR biomarkers and PET scan.

  11. Expected Performance of Ozone Climate Data Records from Ozone Mapping and Profiler Suite Limb Profiler

    Science.gov (United States)

    Xu, P. Q.; Rault, D. F.; Pawson, S.; Wargan, K.; Bhartia, P. K.

    2012-01-01

    The Ozone Mapping and Profiler Suite Limb Profiler (OMPS/LP) was launched on board of the Soumi NPP space platform in late October 2011. It provides ozone-profiling capability with high-vertical resolution from 60 Ian to cloud top. In this study, an end-to-end Observing System Simulation Experiment (OSSE) of OMPS/LP ozone is discussed. The OSSE was developed at NASA's Global Modeling and Assimilation Office (GMAO) using the Goddard Earth Observing System (GEOS-5) data assimilation system. The "truth" for this OSSE is built by assimilating MLS profiles and OMI ozone columns, which is known to produce realistic three-dimensional ozone fields in the stratosphere and upper troposphere. OMPS/LP radiances were computed at tangent points computed by an appropriate orbital model. The OMPS/LP forward RT model, Instrument Models (IMs) and EDR retrieval model were introduced and pseudo-observations derived. The resultant synthetic OMPS/LP observations were evaluated against the "truth" and subsequently these observations were assimilated into GEOS-5. Comparison of this assimilated dataset with the "truth" enables comparisons of the likely uncertainties in 3-D analyses of OMPS/LP data. This study demonstrated the assimilation capabilities of OMPS/LP ozone in GEOS-5, with the monthly, zonal mean (O-A) smaller than 0.02ppmv at all levels, the nns(O-A) close to O.lppmv from 100hPa to 0.2hPa; and the mean(O-B) around the 0.02ppmv for all levels. The monthly zonal mean analysis generally agrees to within 2% of the truth, with larger differences of 2-4% (0.1-0.2ppmv) around 10hPa close to North Pole and in the tropical tropopause region, where the difference is above 20% due to the very low ozone concentrations. These OSSEs demonstrated that, within a single data assimilation system and the assumption that assimilated MLS observations provide a true rendition of the stratosphere, the OMPS/LP ozone data are likely to produce accurate analyses through much of the stratosphere

  12. Polymorphism screening and mapping of nine meat performance-related genes in the pig

    Czech Academy of Sciences Publication Activity Database

    Horák, Pavel; Stratil, Antonín; Svatoňová, Martina; Maštálková, Lucie; Patáková, Jitka; Van Poucke, M.; Bartenschlager, H.; Peelman, L. J.; Geldermann, H.

    2010-01-01

    Roč. 41, č. 3 (2010), s. 334-335 ISSN 0268-9146 R&D Projects: GA AV ČR KJB500450801; GA ČR GA523/09/0844; GA ČR(CZ) GA523/06/1302 Institutional research plan: CEZ:AV0Z50450515 Keywords : genomics * meat performance-related genes * pig Subject RIV: GI - Animal Husbandry ; Breeding Impact factor: 2.203, year: 2010

  13. Polymorphism screening and mapping of nine meat performance-related genes in the pig

    Czech Academy of Sciences Publication Activity Database

    Horák, Pavel; Stratil, Antonín; Svatoňová, Martina; Maštálková, Lucie; Patáková, Jitka; Van Poucke, M.; Bartenschlager, H.; Peelman, L. J.; Geldermann, H.

    2010-01-01

    Roč. 41, č. 3 (2010), s. 334-335 ISSN 0268-9146 R&D Projects: GA AV ČR KJB500450801; GA ČR GA523/09/0844; GA ČR(CZ) GA523/06/1302 Institutional research plan: CEZ:AV0Z50450515 Keywords : genomics * meat performance -related genes * pig Subject RIV: GI - Animal Husbandry ; Breeding Impact factor: 2.203, year: 2010

  14. Map-Based Power-Split Strategy Design with Predictive Performance Optimization for Parallel Hybrid Electric Vehicles

    Directory of Open Access Journals (Sweden)

    Jixiang Fan

    2015-09-01

    Full Text Available In this paper, a map-based optimal energy management strategy is proposed to improve the consumption economy of a plug-in parallel hybrid electric vehicle. In the design of the maps, which provide both the torque split between engine and motor and the gear shift, not only the current vehicle speed and power demand, but also the optimality based on the predicted trajectory of vehicle dynamics are considered. To seek the optimality, the equivalent consumption, which trades off the fuel and electricity usages, is chosen as the cost function. Moreover, in order to decrease the model errors in the process of optimization conducted in the discrete time domain, the variational integrator is employed to calculate the evolution of the vehicle dynamics. To evaluate the proposed energy management strategy, the simulation results performed on a professional GT-Suit simulator are demonstrated and the comparison to a real-time optimization method is also given to show the advantage of the proposed off-line optimization approach.

  15. An internal reference model-based PRF temperature mapping method with Cramer-Rao lower bound noise performance analysis.

    Science.gov (United States)

    Li, Cheng; Pan, Xinyi; Ying, Kui; Zhang, Qiang; An, Jing; Weng, Dehe; Qin, Wen; Li, Kuncheng

    2009-11-01

    The conventional phase difference method for MR thermometry suffers from disturbances caused by the presence of lipid protons, motion-induced error, and field drift. A signal model is presented with multi-echo gradient echo (GRE) sequence using a fat signal as an internal reference to overcome these problems. The internal reference signal model is fit to the water and fat signals by the extended Prony algorithm and the Levenberg-Marquardt algorithm to estimate the chemical shifts between water and fat which contain temperature information. A noise analysis of the signal model was conducted using the Cramer-Rao lower bound to evaluate the noise performance of various algorithms, the effects of imaging parameters, and the influence of the water:fat signal ratio in a sample on the temperature estimate. Comparison of the calculated temperature map and thermocouple temperature measurements shows that the maximum temperature estimation error is 0.614 degrees C, with a standard deviation of 0.06 degrees C, confirming the feasibility of this model-based temperature mapping method. The influence of sample water:fat signal ratio on the accuracy of the temperature estimate is evaluated in a water-fat mixed phantom experiment with an optimal ratio of approximately 0.66:1. (c) 2009 Wiley-Liss, Inc.

  16. Beethoven recordings reviewed: a systematic method for mapping the content of music performance criticism.

    Science.gov (United States)

    Alessandri, Elena; Williamson, Victoria J; Eiholzer, Hubert; Williamon, Aaron

    2015-01-01

    Critical reviews offer rich data that can be used to investigate how musical experiences are conceptualized by expert listeners. However, these data also present significant challenges in terms of organization, analysis, and interpretation. This study presents a new systematic method for examining written responses to music, tested on a substantial corpus of music criticism. One hundred critical reviews of Beethoven's piano sonata recordings, published in the Gramophone between August 1934 and July 2010, were selected using in-depth data reduction (qualitative/quantitative approach). The texts were then examined using thematic analysis in order to generate a visual descriptive model of expert critical review. This model reveals how the concept of evaluation permeates critical review. It also distinguishes between two types of descriptors. The first characterizes the performance in terms of specific actions or features of the musical sound (musical parameters, technique, and energy); the second appeals to higher-order properties (artistic style, character and emotion, musical structure, communicativeness) or assumed performer qualities (understanding, intentionality, spontaneity, sensibility, control, and care). The new model provides a methodological guide and conceptual basis for future studies of critical review in any genre.

  17. A Simple and High Performing Rate Control Initialization Method for H.264 AVC Coding Based on Motion Vector Map and Spatial Complexity at Low Bitrate

    Directory of Open Access Journals (Sweden)

    Yalin Wu

    2014-01-01

    Full Text Available The temporal complexity of video sequences can be characterized by motion vector map which consists of motion vectors of each macroblock (MB. In order to obtain the optimal initial QP (quantization parameter for the various video sequences which have different spatial and temporal complexities, this paper proposes a simple and high performance initial QP determining method based on motion vector map and temporal complexity to decide an initial QP in given target bit rate. The proposed algorithm produces the reconstructed video sequences with outstanding and stable quality. For any video sequences, the initial QP can be easily determined from matrices by target bit rate and mapped spatial complexity using proposed mapping method. Experimental results show that the proposed algorithm can show more outstanding objective and subjective performance than other conventional determining methods.

  18. Hippocampal development and the dissociation of cognitive-spatial mapping from motor performance [version 2; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Bryan D. Devan

    2015-09-01

    Full Text Available The publication of a recent article in F1000Research has led to discussion of, and correspondence on a broader issue that has a long history in the fields of neuroscience and psychology.  Namely, is it possible to separate the cognitive components of performance, in this case spatial behavior, from the motoric demands of a task?  Early psychological experiments attempted such a dissociation by studying a form of spatial maze learning where initially rats were allowed to explore a complex maze, termed “latent learning,” before reinforcement was introduced.  Those rats afforded the latent learning experience solved the task faster than those that were not, implying that cognitive map learning during exploration aided in the performance of the task once a motivational component was introduced.  This form of latent learning was interpreted as successfully demonstrating that an exploratory cognitive map component was acquired irrespective of performing a learned spatial response under deprivation/motivational conditions.  The neural substrate for cognitive learning was hypothesized to depend on place cells within the hippocampus.  Subsequent behavioral studies attempted to directly eliminate the motor component of spatial learning by allowing rats to passively view the distal environment before performing any motor response using a task that is widely considered to be hippocampal-dependent.  Latent learning in the water maze, using a passive placement procedure has met with mixed results.  One constraint on viewing cues before performing a learned swimming response to a hidden goal has been the act of dynamically viewing distal cues while moving through a part of the environment where an optimal learned spatial escape response would be observed.  We briefly review these past findings obtained with adult animals to the recent efforts of establishing a “behavioral topology” separating cognitive-spatial learning from tasks differing in

  19. Hippocampal development and the dissociation of cognitive-spatial mapping from motor performance [version 1; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Bryan D. Devan

    2015-08-01

    Full Text Available The publication of a recent article in F1000Research has led to discussion of, and correspondence on a broader issue that has a long history in the fields of neuroscience and psychology.  Namely, is it possible to separate the cognitive components of performance, in this case spatial behavior, from the motoric demands of a task?  Early psychological experiments attempted such a dissociation by studying a form of spatial maze learning where initially rats were allowed to explore a complex maze, termed “latent learning,” before reinforcement was introduced.  Those rats afforded the latent learning experience solved the task faster than those that were not, implying that cognitive map learning during exploration aided in the performance of the task once a motivational component was introduced.  This form of latent learning was interpreted as successfully demonstrating that an exploratory cognitive map component was acquired irrespective of performing a learned spatial response under deprivation/motivational conditions.  The neural substrate for cognitive learning was hypothesized to depend on place cells within the hippocampus.  Subsequent behavioral studies attempted to directly eliminate the motor component of spatial learning by allowing rats to passively view the distal environment before performing any motor response using a task that is widely considered to be hippocampal-dependent.  Latent learning in the water maze, using a passive placement procedure has met with mixed results.  One constraint on viewing cues before performing a learned swimming response to a hidden goal has been the act of dynamically viewing distal cues while moving through a part of the environment where an optimal learned spatial escape response would be observed.  We briefly review these past findings obtained with adult animals to the recent efforts of establishing a “behavioral topology” separating cognitive-spatial learning from tasks differing in

  20. Mapping the knowledge base for maritime health: 4 safety and performance at sea.

    Science.gov (United States)

    Carter, Tim

    2011-01-01

    There is very little recent investigative work on the contribution of health related impairment and disability to either accident risks or to reduced performance at sea, the only exception being studies on fatigue and parallel data on sleep related incidents. Incidents where health related impairment, other than fatigue, has contributed are very rarely found in reports of maritime accident investigations. This may either indicate the irrelevance of these forms of impairment to accidents or alternatively point to the effectiveness of existing control measures. The main approach to risk reduction is by the application of fitness criteria to seafarers during medical examinations. Where there is a knowledge base it is either, as in the case of vision, a very old one that relates to patterns of visual task that differ markedly from those in modern shipping or, as with hearing, is based on untested assumptions about the levels of impairment that will prevent effective communications at sea. There are practical limitations to the assessment of cognitive functions as these encompass such a wide range of impairments from those associated with fatigue, medication, or substance abuse to those relating to age or to the risks of sudden incapacitation from a pre-existing illness. Physical capability can be assessed but only in limited ways in the course of a medical examination. In the absence of clear evidence of accident risks associated with health-related impairments or disabilities it is unlikely that there will be pressure to update criteria that appear to be providing satisfactory protection. As capability is related to the tasks performed, investigations need to integrate information on ergonomic and organizational aspects with that on health and impairment. Criteria that may select seafarers with health- -related impairment need to be reviewed wherever the task demands in modern shipping have changed, in order to relax or modify them where indicated in order to reduce

  1. Influence Model Assisted Learning Cycle Mind Map to Achievement Physics Laboratory Judging from the performance Grade VIII SMPN 1 Rejoso Pasuruan

    OpenAIRE

    Ary Analisa Rahma

    2014-01-01

    Pengaruh Model Siklus Belajar Berbantuan Mind Map terhadap Prestasi Belajar Fisika Ditinjau dari Kinerja Laboratorium Siswa Kelas VIII SMPN 1 Rejoso Kabupaten Pasuruan Abstract: This study aimed to examine the effect of the learning cycle models aided the mind map on the learning achievement in terms of the performance of laboratory physics class VIII student on light material in SMP Negeri 1 Rejoso Pasuruan. This study is a quasi-experimental research. The research design used is a 2 x 2...

  2. Does cognitive performance map to categorical diagnoses of schizophrenia, schizoaffective disorder and bipolar disorder? A discriminant functions analysis.

    Science.gov (United States)

    Van Rheenen, Tamsyn E; Bryce, Shayden; Tan, Eric J; Neill, Erica; Gurvich, Caroline; Louise, Stephanie; Rossell, Susan L

    2016-03-01

    Despite known overlaps in the pattern of cognitive impairments in individuals with bipolar disorder (BD), schizophrenia (SZ) and schizoaffective disorder (SZA), few studies have examined the extent to which cognitive performance validates traditional diagnostic boundaries in these groups. Individuals with SZ (n=49), schizoaffective disorder (n=33) and BD (n=35) completed a battery of cognitive tests measuring the domains of processing speed, immediate memory, semantic memory, learning, working memory, executive function and sustained attention. A discriminant functions analysis revealed a significant function comprising semantic memory, immediate memory and processing speed that maximally separated patients with SZ from those with BD. Initial classification scores on the basis of this function showed modest diagnostic accuracy, owing in part to the misclassification of SZA patients as having SZ. When SZA patients were removed from the model, a second cross-validated classifier yielded slightly improved diagnostic accuracy and a single function solution, of which semantic memory loaded most heavily. A cluster of non-executive cognitive processes appears to have some validity in mapping onto traditional nosological boundaries. However, since semantic memory performance was the primary driver of the discrimination between BD and SZ, it is possible that performance differences between the disorders in this cognitive domain in particular, index separate underlying aetiologies. Copyright © 2015 Elsevier B.V. All rights reserved.

  3. The design and performance of a velocity map imaging spectrometer for the study of molecular photoionisation dynamics

    Energy Technology Data Exchange (ETDEWEB)

    Holland, D.M.P., E-mail: david.holland@stfc.ac.uk [Daresbury Laboratory, Daresbury, Warrington, Cheshire WA4 4AD (United Kingdom); Shaw, D.A. [Daresbury Laboratory, Daresbury, Warrington, Cheshire WA4 4AD (United Kingdom)

    2012-12-10

    Highlights: Black-Right-Pointing-Pointer Velocity map imaging spectrometer optimised for molecular photoionisation dynamics. Black-Right-Pointing-Pointer Kinetic energy distribution of O{sup +} fragments measured. Black-Right-Pointing-Pointer Effect of autoionisation on photoelectron vibrational populations studied. -- Abstract: The design, construction and performance of a velocity map imaging spectrometer for the study of molecular photoionisation dynamics is described. The spectrometer has been optimised for the efficient collection and detection of particles (electrons or positively charged ions) generated through the interaction of gas phase molecules with synchrotron radiation. A double Einzel lens, incorporated into the flight tube, enhances the collection efficiency of energetic particles. Computer modelling has been used to trace the trajectories of charged particles through the spectrometer and to assess the image quality. A time and position sensitive delay-line detector is used to record the images. Results from two experimental studies are presented to illustrate the capabilities of the spectrometer. In the first, the effect of electronic autoionisation on the vibrationally resolved photoelectron branching ratios of the N{sub 2}{sup +} X {sup 2}{Sigma}{sub g}{sup +} state has been investigated in an excitation range where prominent structure due to Rydberg states occurs in the ion yield curve. The results show that autoionisation leads to rotational branch populations that differ from those observed in direct, non-resonant, photoionisation. In the second, the kinetic energy distribution and the angular distribution of O{sup +} fragments formed in the dissociative photoionisation of molecular oxygen have been measured. The timing properties of the detector have allowed O{sup +} fragments to be separated from O{sub 2}{sup +} parent ions using time-of-flight techniques.

  4. Prebiotic Low Sugar Chocolate Dairy Desserts: Physical and Optical Characteristics and Performance of PARAFAC and PCA Preference Map.

    Science.gov (United States)

    Morais, E C; Esmerino, E A; Monteiro, R A; Pinheiro, C M; Nunes, C A; Cruz, A G; Bolini, Helena M A

    2016-01-01

    The addition of prebiotic and sweeteners in chocolate dairy desserts opens up new opportunities to develop dairy desserts that besides having a lower calorie intake still has functional properties. In this study, prebiotic low sugar dairy desserts were evaluated by 120 consumers using a 9-point hedonic scale, in relation to the attributes of appearance, aroma, flavor, texture, and overall liking. Internal preference map using parallel factor analysis (PARAFAC) and principal component analysis (PCA) was performed using the consumer data. In addition, physical (texture profile) and optical (instrumental color) analyses were also performed. Prebiotic dairy desserts containing sucrose and sucralose were equally liked by the consumers. These samples were characterized by firmness and gumminess, which can be considered drivers of liking by the consumers. Optimization of the prebiotic low sugar dessert formulation should take in account the choice of ingredients that contribute in a positive manner for these parameters. PARAFAC allowed the extraction of more relevant information in relation to PCA, demonstrating that consumer acceptance analysis can be evaluated by simultaneously considering several attributes. Multiple factor analysis reported Rv value of 0.964, suggesting excellent concordance for both methods. © 2015 Institute of Food Technologists®

  5. Adjusting the specificity of an engine map based on the sensitivity of an engine control parameter relative to a performance variable

    Science.gov (United States)

    Jiang, Li; Lee, Donghoon; Yilmaz, Hakan; Stefanopoulou, Anna

    2014-10-28

    Methods and systems for engine control optimization are provided. A first and a second operating condition of a vehicle engine are detected. An initial value is identified for a first and a second engine control parameter corresponding to a combination of the detected operating conditions according to a first and a second engine map look-up table. The initial values for the engine control parameters are adjusted based on a detected engine performance variable to cause the engine performance variable to approach a target value. A first and a second sensitivity of the engine performance variable are determined in response to changes in the engine control parameters. The first engine map look-up table is adjusted when the first sensitivity is greater than a threshold, and the second engine map look-up table is adjusted when the second sensitivity is greater than a threshold.

  6. Mapping out Map Libraries

    Directory of Open Access Journals (Sweden)

    Ferjan Ormeling

    2008-09-01

    Full Text Available Discussing the requirements for map data quality, map users and their library/archives environment, the paper focuses on the metadata the user would need for a correct and efficient interpretation of the map data. For such a correct interpretation, knowledge of the rules and guidelines according to which the topographers/cartographers work (such as the kind of data categories to be collected, and the degree to which these rules and guidelines were indeed followed are essential. This is not only valid for the old maps stored in our libraries and archives, but perhaps even more so for the new digital files as the format in which we now have to access our geospatial data. As this would be too much to ask from map librarians/curators, some sort of web 2.0 environment is sought where comments about data quality, completeness and up-to-dateness from knowledgeable map users regarding the specific maps or map series studied can be collected and tagged to scanned versions of these maps on the web. In order not to be subject to the same disadvantages as Wikipedia, where the ‘communis opinio’ rather than scholarship, seems to be decisive, some checking by map curators of this tagged map use information would still be needed. Cooperation between map curators and the International Cartographic Association ( ICA map and spatial data use commission to this end is suggested.

  7. A fully automatic tool to perform accurate flood mapping by merging remote sensing imagery and ancillary data

    Science.gov (United States)

    D'Addabbo, Annarita; Refice, Alberto; Lovergine, Francesco; Pasquariello, Guido

    2016-04-01

    Flooding is one of the most frequent and expansive natural hazard. High-resolution flood mapping is an essential step in the monitoring and prevention of inundation hazard, both to gain insight into the processes involved in the generation of flooding events, and from the practical point of view of the precise assessment of inundated areas. Remote sensing data are recognized to be useful in this respect, thanks to the high resolution and regular revisit schedules of state-of-the-art satellites, moreover offering a synoptic overview of the extent of flooding. In particular, Synthetic Aperture Radar (SAR) data present several favorable characteristics for flood mapping, such as their relative insensitivity to the meteorological conditions during acquisitions, as well as the possibility of acquiring independently of solar illumination, thanks to the active nature of the radar sensors [1]. However, flood scenarios are typical examples of complex situations in which different factors have to be considered to provide accurate and robust interpretation of the situation on the ground: the presence of many land cover types, each one with a particular signature in presence of flood, requires modelling the behavior of different objects in the scene in order to associate them to flood or no flood conditions [2]. Generally, the fusion of multi-temporal, multi-sensor, multi-resolution and/or multi-platform Earth observation image data, together with other ancillary information, seems to have a key role in the pursuit of a consistent interpretation of complex scenes. In the case of flooding, distance from the river, terrain elevation, hydrologic information or some combination thereof can add useful information to remote sensing data. Suitable methods, able to manage and merge different kind of data, are so particularly needed. In this work, a fully automatic tool, based on Bayesian Networks (BNs) [3] and able to perform data fusion, is presented. It supplies flood maps

  8. Homozygosity of single nucleotide polymorphisms in the 3' region of the canine estrogen receptor 1 gene is greater in Toy Poodles than in Miniature Dachshunds and Chihuahuas.

    Science.gov (United States)

    Pathirana, Indunil N; Tanaka, Kakeru; Kawate, Noritoshi; Tsuji, Makoto; Hatoya, Shingo; Inaba, Toshio; Tamada, Hiromichi

    2011-06-01

    Differences in the distribution of single nucleotide polymorphisms (SNPs) and haplotypes in the estrogen receptor α gene (ESR1) were examined in Miniature Dachshunds (n = 48), Chihuahuas (n = 20) and Toy Poodles (n = 18). Five DNA fragments located in the 40-kb region at the 3' end of ESR1 were amplified by polymerase chain reaction and were directly sequenced. We compared allele, genotype and estimated haplotype frequencies at each SNP in the 3' end of ESR1 for these three breeds of small dog. The frequency of the major allele and the genotype frequency of the major allele homozygotes, were significantly higher in Toy Poodles for five SNPs (SNP #5, #14-17) than in Miniature Dachshunds, and significantly higher in Toy Poodles than Chihuahuas for three SNPs (SNP #15-17). A common haplotype block was identified in an approximately 20-kb region encompassing four SNPs (SNPs # 14-17). The frequencies of the most abundant estimated haplotype (GTTG) and GTTG homozygotes were significantly higher in Toy Poodles than in the other two breeds. These results imply that homozygosity for the allele, genotype and haplotype distribution within the block at the 3' end of ESR1 is greater in Toy Poodles than in Miniature Dachshunds and Chihuahuas. © 2011 The Authors; Animal Science Journal © 2011 Japanese Society of Animal Science.

  9. Comparing the performance of cluster random sampling and integrated threshold mapping for targeting trachoma control, using computer simulation.

    Directory of Open Access Journals (Sweden)

    Jennifer L Smith

    Full Text Available Implementation of trachoma control strategies requires reliable district-level estimates of trachomatous inflammation-follicular (TF, generally collected using the recommended gold-standard cluster randomized surveys (CRS. Integrated Threshold Mapping (ITM has been proposed as an integrated and cost-effective means of rapidly surveying trachoma in order to classify districts according to treatment thresholds. ITM differs from CRS in a number of important ways, including the use of a school-based sampling platform for children aged 1-9 and a different age distribution of participants. This study uses computerised sampling simulations to compare the performance of these survey designs and evaluate the impact of varying key parameters.Realistic pseudo gold standard data for 100 districts were generated that maintained the relative risk of disease between important sub-groups and incorporated empirical estimates of disease clustering at the household, village and district level. To simulate the different sampling approaches, 20 clusters were selected from each district, with individuals sampled according to the protocol for ITM and CRS. Results showed that ITM generally under-estimated the true prevalence of TF over a range of epidemiological settings and introduced more district misclassification according to treatment thresholds than did CRS. However, the extent of underestimation and resulting misclassification was found to be dependent on three main factors: (i the district prevalence of TF; (ii the relative risk of TF between enrolled and non-enrolled children within clusters; and (iii the enrollment rate in schools.Although in some contexts the two methodologies may be equivalent, ITM can introduce a bias-dependent shift as prevalence of TF increases, resulting in a greater risk of misclassification around treatment thresholds. In addition to strengthening the evidence base around choice of trachoma survey methodologies, this study illustrates

  10. SU-F-T-238: Analyzing the Performance of MapCHECK2 and Delta4 Quality Assurance Phantoms in IMRT and VMAT Plans

    Energy Technology Data Exchange (ETDEWEB)

    Lu, SH; Tsai, YC; Lan, HT; Wen, SY; Chen, LH; Kuo, SH; Wang, CW [National Taiwan University Hospital, Taipei City, Taiwan (China)

    2016-06-15

    Purpose: Intensity-modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) have been widely investigated for use in radiotherapy and found to have a highly conformal dose distribution. Delta{sup 4} is a novel cylindrical phantom consisting of 1069 p-type diodes with true treatments measured in the 3D target volume. The goal of this study was to compare the performance of a Delta{sup 4} diode array for IMRT and VMAT planning with ion chamber and MapCHECK2. Methods: Fifty-four IMRT (n=9) and VMAT (n=45) plans were imported to Philips Pinnacle Planning System 9.2 for recalculation with a solid water phantom, MapCHECK2, and the Delta4 phantom. To evaluate the difference between the measured and calculated dose, we used MapCHECK2 and Delta{sup 4} for a dose-map comparison and an ion chamber (PTW 31010 Semiflex 0.125 cc) for a point-dose comparison. Results: All 54 plans met the criteria of <3% difference for the point dose (at least two points) by ion chamber. The mean difference was 0.784% with a standard deviation of 1.962%. With a criteria of 3 mm/3% in a gamma analysis, the average passing rates were 96.86%±2.19% and 98.42%±1.97% for MapCHECK2 and Delta{sup 4}, respectively. The student t-test of MapCHECK2/Delta{sup 4}, ion chamber/Delta{sup 4}, and ion chamber/MapCHECK2 were 0.0008, 0.2944, and 0.0002, respectively. There was no significant difference in passing rates between MapCHECK2 and Delta{sup 4} for the IMRT plan (p = 0.25). However, a higher pass rate was observed in Delta{sup 4} (98.36%) as compared to MapCHECK2 (96.64%, p < 0.0001) for the VMAT plan. Conclusion: The Pinnacle planning system can accurately calculate doses for VMAT and IMRT plans. The Delta{sup 4} shows a similar result when compared to ion chamber and MapCHECK2, and is an efficient tool for patient-specific quality assurance, especially for rotation therapy.

  11. Projective mapping

    DEFF Research Database (Denmark)

    Dehlholm, Christian; Brockhoff, Per B.; Bredie, Wender Laurentius Petrus

    2012-01-01

    by the practical testing environment. As a result of the changes, a reasonable assumption would be to question the consequences caused by the variations in method procedures. Here, the aim is to highlight the proven or hypothetic consequences of variations of Projective Mapping. Presented variations will include...... instructions and influence heavily the product placements and the descriptive vocabulary (Dehlholm et.al., 2012b). The type of assessors performing the method influences results with an extra aspect in Projective Mapping compared to more analytical tests, as the given spontaneous perceptions are much dependent......Projective Mapping (Risvik et.al., 1994) and its Napping (Pagès, 2003) variations have become increasingly popular in the sensory field for rapid collection of spontaneous product perceptions. It has been applied in variations which sometimes are caused by the purpose of the analysis and sometimes...

  12. Homozygosity for HLA group 2 alleles predicts treatment failure with interferon-α and ribavirin in chronic hepatitis C virus genotype 1 infection.

    Science.gov (United States)

    Collison, Meadhbh; Chin, Jun Liong; Abu Shanab, Ahmed; Mac Nicholas, Ross; Segurado, Ricardo; Coughlan, Suzie; Connell, Jeff; Carr, Michael J; Merriman, Raphael B; McCormick, P Aiden; Hall, William W

    2015-02-01

    Host genetic factors influence treatment responses to antiviral therapy in chronic hepatitis C virus (HCV) infection. We retrospectively investigated associations between host genetic markers and treatment-induced virologic responses to dual therapy with interferon-α and ribavirin in chronically infected HCV genotype 1 (g1)- and genotype 3 (g3)-infected individuals. A total of 171 patients (89 HCV g1 and 82 HCV g3 infected) were investigated for genetic markers influencing treatment-induced sustained virologic response (SVR). Overall, SVR was observed for 46/89 (52%) HCV g1- and 57/82 (70%) HCV g3-infected patients. Of the 4 interleukin 28B (IL28B) single-nucleotide polymorphisms (SNPs), rs12979860 was the host genetic marker most significantly associated with failure to achieve an SVR in HCV g1-infected individuals [P=3.83×10(-4); odds ratio (OR)=5.61; confidence interval (CI)=2.07-15.18] and gave a positive predictive value for treatment failure of 81.3% for minor homozygotes (TT). Using additive (P=3.54×10(-4)) and dominant models (P=3.83×10(-4)), a dosage effect of the T allele was observed, with the dominance term not significant for this SNP. Logistic regression showed an association between HLA-C1/C1 and rapid virologic response in HCV g1 infections with an OR relative to the heterozygote of 10.0 (95% CI: 1.6-62.5, P=0.014). HLA-C2 homozygosity was a significant predictor of nonresponse to treatment in HCV g1-infected individuals (P=0.023).

  13. HFE p.C282Y homozygosity predisposes to rapid serum ferritin rise after menopause: A genotype-stratified cohort study of hemochromatosis in Australian women.

    Science.gov (United States)

    Warne, Charles D; Zaloumis, Sophie G; Bertalli, Nadine A; Delatycki, Martin B; Nicoll, Amanda J; McLaren, Christine E; Hopper, John L; Giles, Graham G; Anderson, Greg J; Olynyk, John K; Powell, Lawrie W; Allen, Katrina J; Gurrin, Lyle C

    2017-04-01

    Women who are homozygous for the p.C282Y mutation in the HFE gene are at much lower risk of iron overload-related disease than p.C282Y homozygous men, presumably because of the iron-depleting effects of menstruation and pregnancy. We used data from a population cohort study to model the impact of menstruation cessation at menopause on serum ferritin (SF) levels in female p.C282Y homozygotes, with p.C282Y/p.H63D simple or compound heterozygotes and those with neither p.C282Y nor p.H63D mutations (HFE wild types) as comparison groups. A sample of the Melbourne Collaborative Cohort Study was selected for the "HealthIron" study (n = 1438) including all HFE p.C282Y homozygotes plus a random sample stratified by HFE-genotype (p.C282Y and p.H63D). The relationship between the natural logarithm of SF and time since menopause was examined using linear mixed models incorporating spline smoothing. For p.C282Y homozygotes, SF increased by a factor of 3.6 (95% CI (1.8, 7.0), P HFE genotype groups increase more gradually and did not show a distinction between premenopausal and postmenopausal SF levels. Only p.C282Y homozygotes had predicted SF exceeding 200 μg/L postmenopause, but the projected SF did not increase the risk of iron overload-related disease. These data provide the first documented evidence that physiological blood loss is a major factor in determining the marked gender difference in expression of p.C282Y homozygosity. © 2016 Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd.

  14. Autoimmune Conditions in 235 Hemochromatosis Probands with HFE C282Y Homozygosity and Their First-Degree Relatives

    Directory of Open Access Journals (Sweden)

    James C. Barton

    2015-01-01

    Full Text Available We performed a retrospective study of autoimmune conditions (ACs in 235 hemochromatosis probands at diagnosis by analyzing age, sex, ACs, history of first-degree family members with ACs (FH, diabetes, heavy ethanol consumption, elevated serum ALT/AST, nonalcoholic fatty liver disease, viral hepatitis, cirrhosis, iron removed to achieve iron depletion (QFe, and positivity for human leukocyte antigen (HLA haplotypes A∗01, B∗08; A∗02, B∗44; A∗03, B∗07; A∗03, B∗14; and A∗29, B∗44. There were 138 men (58.7%. Median followup was 19.6 y. One or more of 19 ACs were diagnosed in each of 35 probands (14.9%. Prevalences of Hashimoto’s thyroiditis, rheumatoid arthritis, and ankylosing spondylitis were 8.1% (95% CI: [5.1, 12.5], 1.7% [0.6, 4.6], and 0.0085 [0.0015, 0.0337], respectively. Eighteen probands (7.7% had a FH. Eight probands with ACs had 9 family members with ACs. In a logistic regression, ACs were less likely in men (odds ratio (OR 0.3 [0.1, 0.6] and more likely in probands with a FH (OR 4.1 [1.4, 11.8]. Overall ACs risk was not significantly associated with QFe or HLA haplotypes. Estimated survival of probands with and without ACs did not differ significantly. We conclude that ACs are common in hemochromatosis probands, especially women and probands with a FH.

  15. High resolution and high sensitivity methods for oligosaccharide mapping and characterization by normal phase high performance liquid chromatography following derivatization with highly fluorescent anthranilic acid.

    Science.gov (United States)

    Anumula, K R; Dhume, S T

    1998-07-01

    Facile labeling of oligosaccharides (acidic and neutral) in a nonselective manner was achieved with highly fluorescent anthranilic acid (AA, 2-aminobenzoic acid) (more than twice the intensity of 2-aminobenzamide, AB) for specific detection at very high sensitivity. Quantitative labeling in acetate-borate buffered methanol (approximately pH 5.0) at 80 degreesC for 60 min resulted in negligible or no desialylation of the oligosaccharides. A high resolution high performance liquid chromatographic method was developed for quantitative oligosaccharide mapping on a polymeric-NH2bonded (Astec) column operating under normal phase and anion exchange (NP-HPAEC) conditions. For isolation of oligosaccharides from the map by simple evaporation, the chromatographic conditions developed use volatile acetic acid-triethylamine buffer (approximately pH 4.0) systems. The mapping and characterization technology was developed using well characterized standard glycoproteins. The fluorescent oligosaccharide maps were similar to the maps obtained by the high pH anion-exchange chromatography with pulsed amperometric detection (HPAEC-PAD), except that the fluorescent maps contained more defined peaks. In the map, the oligosaccharides separated into groups based on charge, size, linkage, and overall structure in a manner similar to HPAEC-PAD with contribution of -COOH function from the label, anthranilic acid. However, selectivity of the column for sialic acid linkages was different. A second dimension normal phase HPLC (NP-HPLC) method was developed on an amide column (TSK Gel amide-80) for separation of the AA labeled neutral complex type and isomeric structures of high mannose type oligosaccharides. The oligosaccharides labeled with AA are compatible with biochemical and biophysical techniques, and use of matrix assisted laser desorption mass spectrometry for rapid determination of oligosaccharide mass map of glycoproteins is demonstrated. High resolution of NP-HPAEC and NP-HPLC methods

  16. Integrating views on support for mid-level health worker performance: a concept mapping study with regional health system actors in rural Guatemala.

    Science.gov (United States)

    Hernández, Alison R; Hurtig, Anna-Karin; Dahlblom, Kjerstin; San Sebastián, Miguel

    2015-10-08

    Mid-level health workers are on the front-lines in underserved areas in many LMICs, and their performance is critical for improving the health of vulnerable populations. However, improving performance in low-resource settings is complex and highly dependent on the organizational context of local health systems. This study aims to examine the views of actors from different levels of a regional health system in Guatemala on actions to support the performance of auxiliary nurses, a cadre of mid-level health workers with a prominent role in public sector service delivery. A concept mapping study was carried out to develop an integrated view on organizational support and identify locally relevant strategies for strengthening performance. A total of 93 regional and district managers, and primary and secondary care health workers participated in generating ideas on actions needed to support auxiliary nurses' performance. Ideas were consolidated into 30 action items, which were structured through sorting and rating exercises, involving a total of 135 of managers and health workers. Maps depicting participants' integrated views on domains of action and dynamics in sub-groups' interests were generated using a sequence of multivariate statistical analyses, and interpreted by regional managers. The combined input of health system actors provided a multi-faceted view of actions needed to support performance, which were organized in six domains, including: Communication and coordination, Tools to orient work, Organizational climate of support, Motivation through recognition, Professional development and Skills development. The nature of relationships across hierarchical levels was identified as a cross-cutting theme. Pattern matching and go-zone maps indicated directions for action based on areas of consensus and difference across sub-groups of actors. This study indicates that auxiliary nurses' performance is interconnected with the performance of other health system actors who

  17. An approach for establishing the performance maps of the sc-CO_2 compressor: Development and qualification by means of CFD simulations

    International Nuclear Information System (INIS)

    Pham, H.S.; Alpy, N.; Ferrasse, J.H.; Boutin, O.; Tothill, M.; Quenaut, J.; Gastaldi, O.; Cadiou, T.; Saez, M.

    2016-01-01

    Highlights: • Ability of CFD to predict the performance of a sc-CO_2 test compressor is shown. • Risk of vapor pockets occurrence inside a scale 1:1 compressor is highlighted. • Limitation of previous performance maps approaches to model the real gas behavior is shown. • A performance maps approach for the sc-CO_2 compressor is proposed and validated. - Abstract: One of the challenges in the performance prediction of the supercritical CO_2 (sc-CO_2) compressor is the real gas behavior of the working fluid near the critical point. This study deals with the establishment of an approach that allows coping with this particularity by dressing compressor performance maps in adequate reduced coordinates (i.e., suitable dimensionless speed and flow parameters inputs and pressure ratio and enthalpy rise outputs), while using CFD for its validation. Two centrifugal compressor designs have been considered in this work. The first one corresponds to a 6 kW small scale component implemented in a test loop at Tokyo Institute of Technology. The second one corresponds to a 38 MW scale 1:1 design considered at an early stage of a project that investigates sc-CO_2 cycle for a Small Modular Reactor application. Numerical results on the former have been successfully confronted with the experimental data to qualify the ability of CFD to provide a performance database. Results on the latter have revealed a significant decrease in the static temperature and pressure during flow acceleration along the leading edge of the impeller blades. In this line, the increased risk of vapor pockets appearance inside a sc-CO_2 compressor has been highlighted and recommendations regarding the choice of the on-design inlet conditions and the compressor design have been given to overcome this concern. CFD results on the scale 1:1 compressor have then been used to evaluate the relevancy of some previous performance maps approaches for a sc-CO_2 compressor application. These include the conventional

  18. Performance of USGS one-year earthquake hazard map for natural and induced seismicity in the central and eastern United States

    Science.gov (United States)

    Brooks, E. M.; Stein, S.; Spencer, B. D.; Salditch, L.; Petersen, M. D.; McNamara, D. E.

    2017-12-01

    Seismicity in the central United States has dramatically increased since 2008 due to the injection of wastewater produced by oil and gas extraction. In response, the USGS created a one-year probabilistic hazard model and map for 2016 to describe the increased hazard posed to the central and eastern United States. Using the intensity of shaking reported to the "Did You Feel It?" system during 2016, we assess the performance of this model. Assessing the performance of earthquake hazard maps for natural and induced seismicity is conceptually similar but has practical differences. Maps that have return periods of hundreds or thousands of years— as commonly used for natural seismicity— can be assessed using historical intensity data that also span hundreds or thousands of years. Several different features stand out when assessing the USGS 2016 seismic hazard model for the central and eastern United States from induced and natural earthquakes. First, the model can be assessed as a forecast in one year, because event rates are sufficiently high to permit evaluation with one year of data. Second, because these models are projections from the previous year thus implicitly assuming that fluid injection rates remain the same, misfit may reflect changes in human activity. Our results suggest that the model was very successful by the metric implicit in probabilistic hazard seismic assessment: namely, that the fraction of sites at which the maximum shaking exceeded the mapped value is comparable to that expected. The model also did well by a misfit metric that compares the spatial patterns of predicted and maximum observed shaking. This was true for both the central and eastern United States as a whole, and for the region within it with the highest amount of seismicity, Oklahoma and its surrounding area. The model performed least well in northern Texas, over-stating hazard, presumably because lower oil and gas prices and regulatory action reduced the water injection volume

  19. Towards a high performance vertex detector based on 3D integration of deep N-well MAPS

    International Nuclear Information System (INIS)

    Re, V

    2010-01-01

    The development of deep N-Well (DNW) CMOS active pixel sensors was driven by the ambitious goal of designing a monolithic device with similar functionalities as in hybrid pixel readout chips, such as pixel-level sparsification and time stamping. The implementation of the DNW MAPS concept in a 3D vertical integration process naturally leads the designer towards putting more intelligence in the chip and in the pixels themselves, achieving novel device structures based on the interconnection of two or more layers fabricated in the same technology. These devices are read out with a data-push scheme that makes it possible to use pixel data for the generation of a flexible level 1 track trigger, based on associative memories, with short latency and high efficiency. This paper gives an update of the present status of DNW MAPS design in both 2D and 3D versions, and presents a discussion of the architectures that are being devised for the Layer 0 of the SuperB Silicon Vertex Tracker.

  20. Towards a high performance vertex detector based on 3D integration of deep N-well MAPS

    Energy Technology Data Exchange (ETDEWEB)

    Re, V, E-mail: valerio.re@unibg.i [University of Bergamo, Department of Industrial Engineering, Viale Marconi 5, 24044 Dalmine (Italy)

    2010-06-15

    The development of deep N-Well (DNW) CMOS active pixel sensors was driven by the ambitious goal of designing a monolithic device with similar functionalities as in hybrid pixel readout chips, such as pixel-level sparsification and time stamping. The implementation of the DNW MAPS concept in a 3D vertical integration process naturally leads the designer towards putting more intelligence in the chip and in the pixels themselves, achieving novel device structures based on the interconnection of two or more layers fabricated in the same technology. These devices are read out with a data-push scheme that makes it possible to use pixel data for the generation of a flexible level 1 track trigger, based on associative memories, with short latency and high efficiency. This paper gives an update of the present status of DNW MAPS design in both 2D and 3D versions, and presents a discussion of the architectures that are being devised for the Layer 0 of the SuperB Silicon Vertex Tracker.

  1. Intellectual disability, muscle weakness and characteristic face in three siblings: A newly described recessive syndrome mapping to 3p24.3-p25.3.

    Science.gov (United States)

    Kariminejad, Ariana; Nafissi, Shahriar; Nilipoor, Yalda; Tavasoli, Alireza; Van Veldhoven, Paul P; Bonnard, Carine; Ng, Yeng Ting; Majoie, Charles B; Reversade, Bruno; Hennekam, Raoul C

    2015-11-01

    We report on a sister and two brothers born to healthy Iranian parents with mild intellectual disability, progressive muscle weakness, and characteristic facies. including highly arched eyebrows, down-slanting palpebral fissures, prominent nasal bridge, prominent nose, columella extending below alae nasi, narrow mouth, narrow palate, and dental caries, and in one of them an inability to abduct the left eye. Electrophysiological studies showed signs of myopathy, and muscle biopsies demonstrated only nonspecific signs. Brain MRIs in two of the sibs showed leukencephalopathy with delayed myelination, frontal and parietal hyperintensities, and hippocampal atrophy in one. We have been unable to find a description of this association of features in literature. Based on the occurrence in siblings, no significant difference in phenotype between the brothers and sister, absence of manifestations in parents, and a likely consanguinity between parents we performed a homozygosity mapping. A single identical-by-descent bloc encompassing 57 genes located at 3p24.3-p25.3 was found to segregate within the family with this phenotype. © 2015 Wiley Periodicals, Inc. © 2015 Wiley Periodicals, Inc.

  2. USH1K, a novel locus for type I Usher syndrome, maps to chromosome 10p11.21-q21.1.

    Science.gov (United States)

    Jaworek, Thomas J; Bhatti, Rashid; Latief, Noreen; Khan, Shaheen N; Riazuddin, Saima; Ahmed, Zubair M

    2012-10-01

    We ascertained two large Pakistani consanguineous families (PKDF231 and PKDF608) segregating profound hearing loss, vestibular dysfunction, and retinitis pigmentosa; the defining features of Usher syndrome type 1 (USH1). To date, seven USH1 loci have been reported. Here, we map a novel locus, USH1K, on chromosome 10p11.21-q21.1. In family PKDF231, we performed a genome-wide linkage screen and found a region of homozygosity shared among the affected individuals at chromosome 10p11.21-q21.1. Meiotic recombination events in family PKDF231 define a critical interval of 11.74 cM (20.20 Mb) bounded by markers D10S1780 (63.83 cM) and D10S546 (75.57 cM). Affected individuals of family PKDF608 were also homozygous for chromosome 10p11.21-q21.1-linked STR markers. Of the 85 genes within the linkage interval, PCDH15, GJD4, FZD4, RET and LRRC18 were sequenced in both families, but no potential pathogenic mutation was identified. The USH1K locus overlaps the non-syndromic deafness locus DFNB33 raising the possibility that the two disorders may be caused by allelic mutations.

  3. Physical mapping of the Bloom syndrome region by the identification of YAC and P1 clones from human chromosome 15 band q26.1

    Energy Technology Data Exchange (ETDEWEB)

    Straughen, J.; Groden, J. [Univ. of Cincinnati College of Medicine, OH (United States); Ciocci, S. [New York Blood Center, NY (United States)] [and others

    1996-07-01

    The gene for Bloom syndrome (BLM) has been mapped to human chromosome 15 band q26.1 by homozygosity mapping. Further refinement of the location of BLM has relied upon linkage-disequilibrium mapping and somatic intragenic recombination. In combination with these mapping approaches and to identify novel DNA markers and probes for the BLM candidate region, a contiguous representation of the 2-Mb region that contains the BLM gene was generated and is presented here. YAC and P1 clones from the region have been identified and ordered by using previously available genetic markers in the region along with newly developed sequence-tagged sites from radiation-restriction map of the 2-Mb region that allowed estimation of the distance between polymorphic microsatellite loci is also reported. This map and the DNA markers derived from it were instrumental in the recent identification of the BLM gene. 25 refs., 3 figs., 3 tabs.

  4. Discrete vs. Continuous Mapping of Facial Electromyography for Human-Machine-Interface Control: Performance and Training Effects

    Science.gov (United States)

    Cler, Meredith J.; Stepp, Cara E.

    2015-01-01

    Individuals with high spinal cord injuries are unable to operate a keyboard and mouse with their hands. In this experiment, we compared two systems using surface electromyography (sEMG) recorded from facial muscles to control an onscreen keyboard to type five-letter words. Both systems used five sEMG sensors to capture muscle activity during five distinct facial gestures that were mapped to five cursor commands: move left, move right, move up, move down, and “click”. One system used a discrete movement and feedback algorithm in which the user produced one quick facial gesture, causing a corresponding discrete movement to an adjacent letter. The other system was continuously updated and allowed the user to control the cursor’s velocity by relative activation between different sEMG channels. Participants were trained on one system for four sessions on consecutive days, followed by one crossover session on the untrained system. Information transfer rates (ITRs) were high for both systems compared to other potential input modalities, both initially and with training (Session 1: 62.1 bits/min, Session 4: 105.1 bits/min). Users of the continuous system showed significantly higher ITRs than the discrete users. Future development will focus on improvements to both systems, which may offer differential advantages for users with various motor impairments. PMID:25616053

  5. The Performance of the Smart Cities in China—A Comparative Study by Means of Self-Organizing Maps and Social Networks Analysis

    Directory of Open Access Journals (Sweden)

    Dong Lu

    2015-06-01

    Full Text Available Smart cities link the city services, citizens, resource and infrastructures together and form the heart of the modern society. As a “smart” ecosystem, smart cities focus on sustainable growth, efficiency, productivity and environmentally friendly development. By comparing with the European Union, North America and other countries, smart cities in China are still in the preliminary stage. This study offers a comparative analysis of ten smart cities in China on the basis of an extensive database covering two time periods: 2005–2007 and 2008–2010. The unsupervised computational neural network self-organizing map (SOM analysis is adopted to map out the various cities based on their performance. The demonstration effect and mutual influences between these ten smart cities are also discussed by using social network analysis. Based on the smart city performance and cluster network, current problems for smart city development in China were pointed out. Future research directions for smart city research are discussed at the end this paper.

  6. Enhanced nonlinearity interval mapping scheme for high-performance simulation-optimization of watershed-scale BMP placement

    Science.gov (United States)

    Zou, Rui; Riverson, John; Liu, Yong; Murphy, Ryan; Sim, Youn

    2015-03-01

    Integrated continuous simulation-optimization models can be effective predictors of a process-based responses for cost-benefit optimization of best management practices (BMPs) selection and placement. However, practical application of simulation-optimization model is computationally prohibitive for large-scale systems. This study proposes an enhanced Nonlinearity Interval Mapping Scheme (NIMS) to solve large-scale watershed simulation-optimization problems several orders of magnitude faster than other commonly used algorithms. An efficient interval response coefficient (IRC) derivation method was incorporated into the NIMS framework to overcome a computational bottleneck. The proposed algorithm was evaluated using a case study watershed in the Los Angeles County Flood Control District. Using a continuous simulation watershed/stream-transport model, Loading Simulation Program in C++ (LSPC), three nested in-stream compliance points (CP)—each with multiple Total Maximum Daily Loads (TMDL) targets—were selected to derive optimal treatment levels for each of the 28 subwatersheds, so that the TMDL targets at all the CP were met with the lowest possible BMP implementation cost. Genetic Algorithm (GA) and NIMS were both applied and compared. The results showed that the NIMS took 11 iterations (about 11 min) to complete with the resulting optimal solution having a total cost of 67.2 million, while each of the multiple GA executions took 21-38 days to reach near optimal solutions. The best solution obtained among all the GA executions compared had a minimized cost of 67.7 million—marginally higher, but approximately equal to that of the NIMS solution. The results highlight the utility for decision making in large-scale watershed simulation-optimization formulations.

  7. Map Usage in Virtual Environments

    National Research Council Canada - National Science Library

    Cevik, Helsin

    1998-01-01

    ... of map representation as an aid in performing navigation tasks. The approach taken was first to determine and then investigate the parameters that affect virtual map representation through an experiment designed specifically for this thesis...

  8. Tracing QTLs for Leaf Blast Resistance and Agronomic Performance of Finger Millet (Eleusine coracana (L. Gaertn. Genotypes through Association Mapping and in silico Comparative Genomics Analyses.

    Directory of Open Access Journals (Sweden)

    M Ramakrishnan

    Full Text Available Finger millet is one of the small millets with high nutritive value. This crop is vulnerable to blast disease caused by Pyricularia grisea, which occurs annually during rainy and winter seasons. Leaf blast occurs at early crop stage and is highly damaging. Mapping of resistance genes and other quantitative trait loci (QTLs for agronomic performance can be of great use for improving finger millet genotypes. Evaluation of one hundred and twenty-eight finger millet genotypes in natural field conditions revealed that leaf blast caused severe setback on agronomic performance for susceptible genotypes, most significant traits being plant height and root length. Plant height was reduced under disease severity while root length was increased. Among the genotypes, IE4795 showed superior response in terms of both disease resistance and better agronomic performance. A total of seven unambiguous QTLs were found to be associated with various agronomic traits including leaf blast resistance by association mapping analysis. The markers, UGEP101 and UGEP95, were strongly associated with blast resistance. UGEP98 was associated with tiller number and UGEP9 was associated with root length and seed yield. Cross species validation of markers revealed that 12 candidate genes were associated with 8 QTLs in the genomes of grass species such as rice, foxtail millet, maize, Brachypodium stacei, B. distachyon, Panicum hallii and switchgrass. Several candidate genes were found proximal to orthologous sequences of the identified QTLs such as 1,4-β-glucanase for leaf blast resistance, cytokinin dehydrogenase (CKX for tiller production, calmodulin (CaM binding protein for seed yield and pectin methylesterase inhibitor (PMEI for root growth and development. Most of these QTLs and their putatively associated candidate genes are reported for first time in finger millet. On validation, these novel QTLs may be utilized in future for marker assisted breeding for the development of

  9. Tracing QTLs for Leaf Blast Resistance and Agronomic Performance of Finger Millet (Eleusine coracana (L.) Gaertn.) Genotypes through Association Mapping and in silico Comparative Genomics Analyses.

    Science.gov (United States)

    Ramakrishnan, M; Antony Ceasar, S; Duraipandiyan, V; Vinod, K K; Kalpana, Krishnan; Al-Dhabi, N A; Ignacimuthu, S

    2016-01-01

    Finger millet is one of the small millets with high nutritive value. This crop is vulnerable to blast disease caused by Pyricularia grisea, which occurs annually during rainy and winter seasons. Leaf blast occurs at early crop stage and is highly damaging. Mapping of resistance genes and other quantitative trait loci (QTLs) for agronomic performance can be of great use for improving finger millet genotypes. Evaluation of one hundred and twenty-eight finger millet genotypes in natural field conditions revealed that leaf blast caused severe setback on agronomic performance for susceptible genotypes, most significant traits being plant height and root length. Plant height was reduced under disease severity while root length was increased. Among the genotypes, IE4795 showed superior response in terms of both disease resistance and better agronomic performance. A total of seven unambiguous QTLs were found to be associated with various agronomic traits including leaf blast resistance by association mapping analysis. The markers, UGEP101 and UGEP95, were strongly associated with blast resistance. UGEP98 was associated with tiller number and UGEP9 was associated with root length and seed yield. Cross species validation of markers revealed that 12 candidate genes were associated with 8 QTLs in the genomes of grass species such as rice, foxtail millet, maize, Brachypodium stacei, B. distachyon, Panicum hallii and switchgrass. Several candidate genes were found proximal to orthologous sequences of the identified QTLs such as 1,4-β-glucanase for leaf blast resistance, cytokinin dehydrogenase (CKX) for tiller production, calmodulin (CaM) binding protein for seed yield and pectin methylesterase inhibitor (PMEI) for root growth and development. Most of these QTLs and their putatively associated candidate genes are reported for first time in finger millet. On validation, these novel QTLs may be utilized in future for marker assisted breeding for the development of fungal

  10. Performance of a fast and high-resolution multi-echo spin-echo sequence for prostate T2 mapping across multiple systems.

    Science.gov (United States)

    van Houdt, Petra J; Agarwal, Harsh K; van Buuren, Laurens D; Heijmink, Stijn W T P J; Haack, Søren; van der Poel, Henk G; Ghobadi, Ghazaleh; Pos, Floris J; Peeters, Johannes M; Choyke, Peter L; van der Heide, Uulke A

    2018-03-01

    To evaluate the performance of a multi-echo spin-echo sequence with k-t undersampling scheme (k-t T 2 ) in prostate cancer. Phantom experiments were performed at five systems to estimate the bias, short-term repeatability, and reproducibility across all systems expressed with the within-subject coefficient of variation (wCV). Monthly measurements were performed on two systems for long-term repeatability estimation. To evaluate clinical repeatability, two T 2 maps (voxel size 0.8 × 0.8 × 3 mm 3 ; 5 min) were acquired at separate visits on one system for 13 prostate cancer patients. Repeatability was assessed per patient in relation to spatial resolution. T 2 values were compared for tumor, peripheral zone, and transition zone. Phantom measurements showed a small bias (median = -0.9 ms) and good short-term repeatability (median wCV = 0.5%). Long-term repeatability was 0.9 and 1.1% and reproducibility between systems was 1.7%. The median bias observed in patients was -1.1 ms. At voxel level, the median wCV was 15%, dropping to 4% for structures of 0.5 cm 3 . The median tumor T 2 values (79 ms) were significantly lower (P < 0.001) than in the peripheral zone (149 ms), but overlapped with the transition zone (91 ms). Reproducible T 2 mapping of the prostate is feasible with good spatial resolution in a clinically reasonable scan time, allowing reliable measurement of T 2 in structures as small as 0.5 cm 3 . Magn Reson Med 79:1586-1594, 2018. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

  11. Site-condition map for Portugal, Western Iberia: methodology and constraints on the performance of Vs30 proxies for stable continental regions in Europe.

    Science.gov (United States)

    Vilanova, S. P.; Narciso, J.; Carvalho, J. P.; Cancela, C.; Lopes, I.; Nemser, E. S.; Borges, J.

    2014-12-01

    Information on the amplification characteristics of the near-surface formations in a regional sense is essential to adequately represent both seismic hazard maps and ground shaking maps. Due to the scarceness of shear-wave velocity data in most regions, several methods have been proposed in order to obtain first order representations of Vs30. These include the surface geology method and the topographic slope method. The latter method has become the standard way for incorporating site effects into regional studies worldwide given the convenience provided by the global Vs30 Internet server. In the framework of project SCENE we developed a shear wave velocity database for Portugal. The database consists of 87 shear-wave velocity depth profiles from a variety of lithological and geological formations. We used an iterative three-step procedure to develop the Vs30 based site-condition map: 1) to define a preliminary set of geologically defined units based on the literature; 2) to calculate the distribution of Vs30 for each unit; and 3) to perform statistical tests in order to estimate the significance of the difference in the Vs30 distribution characteristics between the units. The units were merged according to the results of the statistical tests and the procedure was repeated. We started by classifying the sites into six generalized geological units. The final set consists of three units only: F1 (igneous, metamorphic and old sedimentary rocks); F2 (Neogene and Pleistocene formations); and F3 (Holocene deposits). We used the database to evaluate the performance of Vs30 proxies. The use of proxies based either on geological units or on correlations with the topographic slope shows relatively unbiased total residual distributions of the logarithm of Vs30. However, the performance of the methods varies significantly with the generalized geological unit analyzed. Both methods are biased towards lower values of Vs30 for rock formations. The topographic-slope method is

  12. System of automated map design

    International Nuclear Information System (INIS)

    Ponomarjov, S.Yu.; Rybalko, S.I.; Proskura, N.I.

    1992-01-01

    Preprint 'System of automated map design' contains information about the program shell for construction of territory map, performing level line drawing of arbitrary two-dimension field (in particular, the radionuclide concentration field). The work schedule and data structures are supplied, as well as data on system performance. The preprint can become useful for experts in radioecology and for all persons involved in territory pollution mapping or multi-purpose geochemical mapping. (author)

  13. Spatial mapping of cadmium zinc telluride materials properties and electrical response to improve device yield and performance

    CERN Document Server

    Van Scyoc, J M; Yoon, H; Gilbert, T S; Hilton, N R; Lund, J C; James, R B

    1999-01-01

    Cadmium zinc telluride has experienced tremendous growth in its application to various radiation sensing problems over the last five years. However, there are still issues with yield, particularly of the large volume devices needed for imaging and sensitivity-critical applications. Inhomogeneities of various types and on various length scales currently prevent the fabrication of large devices of high spectral performance. This paper discusses the development of a set of characterization tools for quantifying these inhomogeneities, in order to develop improvement strategies to achieve the desired cadmium zinc telluride crystals for detector fabrication.

  14. Performance-based financing as a health system reform: mapping the key dimensions for monitoring and evaluation

    Science.gov (United States)

    2013-01-01

    Background Performance-based financing is increasingly being applied in a variety of contexts, with the expectation that it can improve the performance of health systems. However, while there is a growing literature on implementation issues and effects on outputs, there has been relatively little focus on interactions between PBF and health systems and how these should be studied. This paper aims to contribute to filling that gap by developing a framework for assessing the interactions between PBF and health systems, focusing on low and middle income countries. In doing so, it elaborates a general framework for monitoring and evaluating health system reforms in general. Methods This paper is based on an exploratory literature review and on the work of a group of academics and PBF practitioners. The group developed ideas for the monitoring and evaluation framework through exchange of emails and working documents. Ideas were further refined through discussion at the Health Systems Research symposium in Beijing in October 2012, through comments from members of the online PBF Community of Practice and Beijing participants, and through discussion with PBF experts in Bergen in June 2013. Results The paper starts with a discussion of definitions, to clarify the core concept of PBF and how the different terms are used. It then develops a framework for monitoring its interactions with the health system, structured around five domains of context, the development process, design, implementation and effects. Some of the key questions for monitoring and evaluation are highlighted, and a systematic approach to monitoring effects proposed, structured according to the health system pillars, but also according to inputs, processes and outputs. Conclusions The paper lays out a broad framework within which indicators can be prioritised for monitoring and evaluation of PBF or other health system reforms. It highlights the dynamic linkages between the domains and the different pillars

  15. Performance-based financing as a health system reform: mapping the key dimensions for monitoring and evaluation.

    Science.gov (United States)

    Witter, Sophie; Toonen, Jurrien; Meessen, Bruno; Kagubare, Jean; Fritsche, György; Vaughan, Kelsey

    2013-09-29

    Performance-based financing is increasingly being applied in a variety of contexts, with the expectation that it can improve the performance of health systems. However, while there is a growing literature on implementation issues and effects on outputs, there has been relatively little focus on interactions between PBF and health systems and how these should be studied. This paper aims to contribute to filling that gap by developing a framework for assessing the interactions between PBF and health systems, focusing on low and middle income countries. In doing so, it elaborates a general framework for monitoring and evaluating health system reforms in general. This paper is based on an exploratory literature review and on the work of a group of academics and PBF practitioners. The group developed ideas for the monitoring and evaluation framework through exchange of emails and working documents. Ideas were further refined through discussion at the Health Systems Research symposium in Beijing in October 2012, through comments from members of the online PBF Community of Practice and Beijing participants, and through discussion with PBF experts in Bergen in June 2013. The paper starts with a discussion of definitions, to clarify the core concept of PBF and how the different terms are used. It then develops a framework for monitoring its interactions with the health system, structured around five domains of context, the development process, design, implementation and effects. Some of the key questions for monitoring and evaluation are highlighted, and a systematic approach to monitoring effects proposed, structured according to the health system pillars, but also according to inputs, processes and outputs. The paper lays out a broad framework within which indicators can be prioritised for monitoring and evaluation of PBF or other health system reforms. It highlights the dynamic linkages between the domains and the different pillars. All of these are also framed within

  16. Dual-source dual-energy CT angiography with virtual non-enhanced images and iodine map for active gastrointestinal bleeding: Image quality, radiation dose and diagnostic performance

    International Nuclear Information System (INIS)

    Sun, Hao; Hou, Xin-Yi; Xue, Hua-Dan; Li, Xiao-Guang; Jin, Zheng-Yu; Qian, Jia-Ming; Yu, Jian-Chun; Zhu, Hua-Dong

    2015-01-01

    in 84 patients, 83 (83/84, 98.8%) of which were confirmed by one or more reference standard. The AUC was 0.935 ± 0.027 and 0.947 ± 0.026 for protocols 1 and 2, respectively. There was no significant difference between protocols 1 and 2 for diagnostic performance (Z = 1.672, P > 0.05). The radiation dose reduction achieved by omitting the TNE acquisition was (30.11 ± 6.32)%. Conclusion: DSDECTA with arterial phase with single-source mode, portal-venous phase with dual-energy mode and post-processing VNE image sets and iodine map could act as an accurate screening method for detection and localization of active GIB with lower radiation dose

  17. Dual-source dual-energy CT angiography with virtual non-enhanced images and iodine map for active gastrointestinal bleeding: Image quality, radiation dose and diagnostic performance

    Energy Technology Data Exchange (ETDEWEB)

    Sun, Hao, E-mail: sunhao_robert@126.com [Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Shuaifuyuan No. 1, Wangfujing Street, Dongcheng District, Beijing 100730 (China); Hou, Xin-Yi, E-mail: hxy_pumc@126.com [Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing (China); Xue, Hua-Dan, E-mail: bjdanna95@hotmail.com [Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Shuaifuyuan No. 1, Wangfujing Street, Dongcheng District, Beijing 100730 (China); Li, Xiao-Guang, E-mail: xglee88@126.com [Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Shuaifuyuan No. 1, Wangfujing Street, Dongcheng District, Beijing 100730 (China); Jin, Zheng-Yu, E-mail: zhengyu_jin@126.com [Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Shuaifuyuan No. 1, Wangfujing Street, Dongcheng District, Beijing 100730 (China); Qian, Jia-Ming, E-mail: qjiaming57@gmail.com [Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing (China); Yu, Jian-Chun, E-mail: yu-jch@163.com [Department of General Surgery, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing (China); Zhu, Hua-Dong, E-mail: huadongzhu@hotmail.com [Department of Emergency, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing (China)

    2015-05-15

    in 84 patients, 83 (83/84, 98.8%) of which were confirmed by one or more reference standard. The AUC was 0.935 ± 0.027 and 0.947 ± 0.026 for protocols 1 and 2, respectively. There was no significant difference between protocols 1 and 2 for diagnostic performance (Z = 1.672, P > 0.05). The radiation dose reduction achieved by omitting the TNE acquisition was (30.11 ± 6.32)%. Conclusion: DSDECTA with arterial phase with single-source mode, portal-venous phase with dual-energy mode and post-processing VNE image sets and iodine map could act as an accurate screening method for detection and localization of active GIB with lower radiation dose.

  18. Mapping species distributions with MAXENT using a geographically biased sample of presence data: a performance assessment of methods for correcting sampling bias.

    Science.gov (United States)

    Fourcade, Yoan; Engler, Jan O; Rödder, Dennis; Secondi, Jean

    2014-01-01

    MAXENT is now a common species distribution modeling (SDM) tool used by conservation practitioners for predicting the distribution of a species from a set of records and environmental predictors. However, datasets of species occurrence used to train the model are often biased in the geographical space because of unequal sampling effort across the study area. This bias may be a source of strong inaccuracy in the resulting model and could lead to incorrect predictions. Although a number of sampling bias correction methods have been proposed, there is no consensual guideline to account for it. We compared here the performance of five methods of bias correction on three datasets of species occurrence: one "virtual" derived from a land cover map, and two actual datasets for a turtle (Chrysemys picta) and a salamander (Plethodon cylindraceus). We subjected these datasets to four types of sampling biases corresponding to potential types of empirical biases. We applied five correction methods to the biased samples and compared the outputs of distribution models to unbiased datasets to assess the overall correction performance of each method. The results revealed that the ability of methods to correct the initial sampling bias varied greatly depending on bias type, bias intensity and species. However, the simple systematic sampling of records consistently ranked among the best performing across the range of conditions tested, whereas other methods performed more poorly in most cases. The strong effect of initial conditions on correction performance highlights the need for further research to develop a step-by-step guideline to account for sampling bias. However, this method seems to be the most efficient in correcting sampling bias and should be advised in most cases.

  19. Topographic mapping

    Science.gov (United States)

    ,

    2008-01-01

    The U.S. Geological Survey (USGS) produced its first topographic map in 1879, the same year it was established. Today, more than 100 years and millions of map copies later, topographic mapping is still a central activity for the USGS. The topographic map remains an indispensable tool for government, science, industry, and leisure. Much has changed since early topographers traveled the unsettled West and carefully plotted the first USGS maps by hand. Advances in survey techniques, instrumentation, and design and printing technologies, as well as the use of aerial photography and satellite data, have dramatically improved mapping coverage, accuracy, and efficiency. Yet cartography, the art and science of mapping, may never before have undergone change more profound than today.

  20. Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy.

    NARCIS (Netherlands)

    Otto, E.A.; Hurd, T.W.; Airik, R.; Chaki, M.; Zhou, W.; Stoetzel, C.; Patil, S.B.; Levy, S.; Ghosh, A.K.; Murga-Zamalloa, C.A.; Reeuwijk, J. van; Letteboer, S.J.F.; Sang, L.; Giles, R.H.; Liu, Q.; Coene, K.L.M.; Estrada-Cuzcano, A.; Collin, R.W.J.; McLaughlin, H.M.; Held, S.; Kasanuki, J.M.; Ramaswami, G.; Conte, J.; Lopez, I.; Washburn, J.; Macdonald, J.; Hu, J.; Yamashita, Y.; Maher, E.R.; Guay-Woodford, L.M.; Neumann, H.P.; Obermuller, N.; Koenekoop, R.K.; Bergmann, C.; Bei, X.; Lewis, R.A.; Katsanis, N.; Lopes, V.; Williams, D.S.; Lyons, R.H.; Dang, C.V.; Brito, D.A.; Dias, M.B.; Zhang, X.; Cavalcoli, J.D.; Nurnberg, G.; Nurnberg, P.; Pierce, E.A.; Jackson, P.K.; Antignac, C.; Saunier, S.; Roepman, R.; Dollfus, H.; Khanna, H.; Hildebrandt, F.

    2010-01-01

    Nephronophthisis-related ciliopathies (NPHP-RC) are recessive disorders that feature dysplasia or degeneration occurring preferentially in the kidney, retina and cerebellum. Here we combined homozygosity mapping with candidate gene analysis by performing 'ciliopathy candidate exome capture' followed

  1. Detrimental Effects of Helium Ion Irradiation on Cognitive Performance and Cortical Levels of MAP-2 in B6D2F1 Mice.

    Science.gov (United States)

    Raber, Jacob; Torres, Eileen Ruth S; Akinyeke, Tunde; Lee, Joanne; Weber Boutros, Sydney J; Turker, Mitchell S; Kronenberg, Amy

    2018-04-20

    The space radiation environment includes helium (⁴He) ions that may impact brain function. As little is known about the effects of exposures to ⁴He ions on the brain, we assessed the behavioral and cognitive performance of C57BL/6J × DBA2/J F1 (B6D2F1) mice three months following irradiation with ⁴He ions (250 MeV/n; linear energy transfer (LET) = 1.6 keV/μm; 0, 21, 42 or 168 cGy). Sham-irradiated mice and mice irradiated with 21 or 168 cGy showed novel object recognition, but mice irradiated with 42 cGy did not. In the passive avoidance test, mice received a slight foot shock in a dark compartment, and latency to re-enter that compartment was assessed 24 h later. Sham-irradiated mice and mice irradiated with 21 or 42 cGy showed a higher latency on Day 2 than Day 1, but the latency to enter the dark compartment in mice irradiated with 168 cGy was comparable on both days. ⁴He ion irradiation, at 42 and 168 cGy, reduced the levels of the dendritic marker microtubule-associated protein-2 (MAP-2) in the cortex. There was an effect of radiation on apolipoprotein E (apoE) levels in the hippocampus and cortex, with higher apoE levels in mice irradiated at 42 cGy than 168 cGy and a trend towards higher apoE levels in mice irradiated at 21 than 168 cGy. In addition, in the hippocampus, there was a trend towards a negative correlation between MAP-2 and apoE levels. While reduced levels of MAP-2 in the cortex might have contributed to the altered performance in the passive avoidance test, it does not seem sufficient to do so. The higher hippocampal and cortical apoE levels in mice irradiated at 42 than 168 cGy might have served as a compensatory protective response preserving their passive avoidance memory. Thus, there were no alterations in behavioral performance in the open filed or depressive-like behavior in the forced swim test, while cognitive impairments were seen in the object recognition and passive avoidance tests, but not in the contextual or cued fear

  2. Detrimental Effects of Helium Ion Irradiation on Cognitive Performance and Cortical Levels of MAP-2 in B6D2F1 Mice

    Directory of Open Access Journals (Sweden)

    Jacob Raber

    2018-04-01

    Full Text Available The space radiation environment includes helium (4He ions that may impact brain function. As little is known about the effects of exposures to 4He ions on the brain, we assessed the behavioral and cognitive performance of C57BL/6J × DBA2/J F1 (B6D2F1 mice three months following irradiation with 4He ions (250 MeV/n; linear energy transfer (LET = 1.6 keV/μm; 0, 21, 42 or 168 cGy. Sham-irradiated mice and mice irradiated with 21 or 168 cGy showed novel object recognition, but mice irradiated with 42 cGy did not. In the passive avoidance test, mice received a slight foot shock in a dark compartment, and latency to re-enter that compartment was assessed 24 h later. Sham-irradiated mice and mice irradiated with 21 or 42 cGy showed a higher latency on Day 2 than Day 1, but the latency to enter the dark compartment in mice irradiated with 168 cGy was comparable on both days. 4He ion irradiation, at 42 and 168 cGy, reduced the levels of the dendritic marker microtubule-associated protein-2 (MAP-2 in the cortex. There was an effect of radiation on apolipoprotein E (apoE levels in the hippocampus and cortex, with higher apoE levels in mice irradiated at 42 cGy than 168 cGy and a trend towards higher apoE levels in mice irradiated at 21 than 168 cGy. In addition, in the hippocampus, there was a trend towards a negative correlation between MAP-2 and apoE levels. While reduced levels of MAP-2 in the cortex might have contributed to the altered performance in the passive avoidance test, it does not seem sufficient to do so. The higher hippocampal and cortical apoE levels in mice irradiated at 42 than 168 cGy might have served as a compensatory protective response preserving their passive avoidance memory. Thus, there were no alterations in behavioral performance in the open filed or depressive-like behavior in the forced swim test, while cognitive impairments were seen in the object recognition and passive avoidance tests, but not in the contextual or cued

  3. Autozygosity mapping of a large consanguineous Pakistani family reveals a novel non-syndromic autosomal recessive mental retardation locus on 11p15-tel

    DEFF Research Database (Denmark)

    Rehman, Shoaib ur; Baig, Shahid Mahmood; Eiberg, Hans

    2011-01-01

    done in all sampled individuals in the family. The nuclear central loop in the five generation family showed homozygosity for a 6-Mb telomeric region on 11p15, whereas all other linkage regions were excluded by calculation of logarithm of odds (LOD) for the SNP microarray data. A maximum LOD score of Z......Autosomal recessive inherited mental retardation is an extremely heterogeneous disease and accounts for approximately 25% of all non-syndromic mental retardation cases. Autozygosity mapping of a large consanguineous Pakistani family revealed a novel locus for non-syndromic autosomal recessive...

  4. Concept Mapping

    Science.gov (United States)

    Technology & Learning, 2005

    2005-01-01

    Concept maps are graphical ways of working with ideas and presenting information. They reveal patterns and relationships and help students to clarify their thinking, and to process, organize and prioritize. Displaying information visually--in concept maps, word webs, or diagrams--stimulates creativity. Being able to think logically teaches…

  5. MAP17 Is a Necessary Activator of Renal Na+/Glucose Cotransporter SGLT2

    Science.gov (United States)

    Coady, Michael J.; El Tarazi, Abdulah; Santer, René; Bissonnette, Pierre; Sasseville, Louis J.; Calado, Joaquim; Lussier, Yoann; Dumayne, Christopher; Bichet, Daniel G.

    2017-01-01

    The renal proximal tubule reabsorbs 90% of the filtered glucose load through the Na+-coupled glucose transporter SGLT2, and specific inhibitors of SGLT2 are now available to patients with diabetes to increase urinary glucose excretion. Using expression cloning, we identified an accessory protein, 17 kDa membrane-associated protein (MAP17), that increased SGLT2 activity in RNA-injected Xenopus oocytes by two orders of magnitude. Significant stimulation of SGLT2 activity also occurred in opossum kidney cells cotransfected with SGLT2 and MAP17. Notably, transfection with MAP17 did not change the quantity of SGLT2 protein at the cell surface in either cell type. To confirm the physiologic relevance of the MAP17–SGLT2 interaction, we studied a cohort of 60 individuals with familial renal glucosuria. One patient without any identifiable mutation in the SGLT2 coding gene (SLC5A2) displayed homozygosity for a splicing mutation (c.176+1G>A) in the MAP17 coding gene (PDZK1IP1). In the proximal tubule and in other tissues, MAP17 is known to interact with PDZK1, a scaffolding protein linked to other transporters, including Na+/H+ exchanger 3, and to signaling pathways, such as the A-kinase anchor protein 2/protein kinase A pathway. Thus, these results provide the basis for a more thorough characterization of SGLT2 which would include the possible effects of its inhibition on colocalized renal transporters. PMID:27288013

  6. Mapping racism.

    Science.gov (United States)

    Moss, Donald B

    2006-01-01

    The author uses the metaphor of mapping to illuminate a structural feature of racist thought, locating the degraded object along vertical and horizontal axes. These axes establish coordinates of hierarchy and of distance. With the coordinates in place, racist thought begins to seem grounded in natural processes. The other's identity becomes consolidated, and parochialism results. The use of this kind of mapping is illustrated via two patient vignettes. The author presents Freud's (1905, 1927) views in relation to such a "mapping" process, as well as Adorno's (1951) and Baldwin's (1965). Finally, the author conceptualizes the crucial status of primitivity in the workings of racist thought.

  7. Panencephalopathic Creutzfeldt-Jakob disease with distinct pattern of prion protein deposition in a patient with D178N mutation and homozygosity for valine at codon 129 of the prion protein Gene.

    Science.gov (United States)

    Marcon, Gabriella; Indaco, Antonio; Di Fede, Giuseppe; Suardi, Silvia; Finato, Nicoletta; Moretti, Valentino; Micoli, Sandro; Fociani, Paolo; Zerbi, Pietro; Pincherle, Alessandro; Redaelli, Veronica; Tagliavini, Fabrizio; Giaccone, Giorgio

    2014-03-01

    Prion diseases include sporadic, acquired and genetic forms linked to mutations of the prion protein (PrP) gene (PRNP). In subjects carrying the D178N PRNP mutation, distinct phenotypes can be observed, depending on the methionine/valine codon 129 polymorphism. We present here a 53-year-old woman with D178N mutation in the PRNP gene and homozygosity for valine at codon 129. The disease started at age 47 with memory deficits, progressive cognitive impairment and ataxia. The clinical picture slowly worsened to a state of akinetic mutism in about 2 years and the disease course was 6 years. The neuropathologic examination demonstrated severe diffuse cerebral atrophy with neuronal loss, spongiosis and marked myelin loss and tissue rarefaction in the hemispheric white matter, configuring panencephalopathic Creutzfeldt-Jakob disease. PrP deposition was present in the cerebral cortex, basal ganglia and cerebellum with diffuse synaptic-type pattern of immunoreactivity and clusters of countless, small PrP deposits, particularly evident in the lower cortical layers, in the striatum and in the molecular layer of the cerebellum. Western blot analysis showed the presence of type 1 PrP(Sc) (Parchi classification). These findings underline the clear-cut distinction between the neuropathological features of Creutzfeldt-Jakob disease associated with D178N PRNP mutation and those of fatal familial insomnia. © 2013 International Society of Neuropathology.

  8. PAU/GNSS-R: Implementation, Performance and First Results of a Real-Time Delay-Doppler Map Reflectometer Using Global Navigation Satellite System Signals

    Directory of Open Access Journals (Sweden)

    Enric Valencia

    2008-05-01

    Full Text Available Signals from Global Navigation Satellite Systems (GNSS were originally conceived for position and speed determination, but they can be used as signals of opportunity as well. The reflection process over a given surface modifies the properties of the scattered signal, and therefore, by processing the reflected signal, relevant geophysical data regarding the surface under study (land, sea, ice… can be retrieved. In essence, a GNSS-R receiver is a multi-channel GNSS receiver that computes the received power from a given satellite at a number of different delay and Doppler bins of the incoming signal. The first approaches to build such a receiver consisted of sampling and storing the scattered signal for later post-processing. However, a real-time approach to the problem is desirable to obtain immediately useful geophysical variables and reduce the amount of data. The use of FPGA technology makes this possible, while at the same time the system can be easily reconfigured. The signal tracking and processing constraints made necessary to fully design several new blocks. The uniqueness of the implemented system described in this work is the capability to compute in real-time Delay-Doppler maps (DDMs either for four simultaneous satellites or just one, but with a larger number of bins. The first tests have been conducted from a cliff over the sea and demonstrate the successful performance of the instrument to compute DDMs in real-time from the measured reflected GNSS/R signals. The processing of these measurements shall yield quantitative relationships between the sea state (mainly driven by the surface wind and the swell and the overall DDM shape. The ultimate goal is to use the DDM shape to correct the sea state influence on the L-band brightness temperature to improve the retrieval of the sea surface salinity (SSS.

  9. Genetic Mapping

    Science.gov (United States)

    ... greatly advanced genetics research. The improved quality of genetic data has reduced the time required to identify a ... cases, a matter of months or even weeks. Genetic mapping data generated by the HGP's laboratories is freely accessible ...

  10. The National Map - Orthoimagery

    Science.gov (United States)

    Mauck, James; Brown, Kim; Carswell, William J.

    2009-01-01

    Orthorectified digital aerial photographs and satellite images of 1-meter (m) pixel resolution or finer make up the orthoimagery component of The National Map. The process of orthorectification removes feature displacements and scale variations caused by terrain relief and sensor geometry. The result is a combination of the image characteristics of an aerial photograph or satellite image and the geometric qualities of a map. These attributes allow users to: *Measure distance *Calculate areas *Determine shapes of features *Calculate directions *Determine accurate coordinates *Determine land cover and use *Perform change detection *Update maps The standard digital orthoimage is a 1-m or finer resolution, natural color or color infra-red product. Most are now produced as GeoTIFFs and accompanied by a Federal Geographic Data Committee (FGDC)-compliant metadata file. The primary source for 1-m data is the National Agriculture Imagery Program (NAIP) leaf-on imagery. The U.S. Geological Survey (USGS) utilizes NAIP imagery as the image layer on its 'Digital- Map' - a new generation of USGS topographic maps (http://nationalmap.gov/digital_map). However, many Federal, State, and local governments and organizations require finer resolutions to meet a myriad of needs. Most of these images are leaf-off, natural-color products at resolutions of 1-foot (ft) or finer.

  11. Affective Maps

    DEFF Research Database (Denmark)

    Salovaara-Moring, Inka

    . In particular, mapping environmental damage, endangered species, and human made disasters has become one of the focal point of affective knowledge production. These ‘more-than-humangeographies’ practices include notions of species, space and territory, and movement towards a new political ecology. This type...... of digital cartographies has been highlighted as the ‘processual turn’ in critical cartography, whereas in related computational journalism it can be seen as an interactive and iterative process of mapping complex and fragile ecological developments. This paper looks at computer-assisted cartography as part...

  12. New machine learning tools for predictive vegetation mapping after climate change: Bagging and Random Forest perform better than Regression Tree Analysis

    Science.gov (United States)

    L.R. Iverson; A.M. Prasad; A. Liaw

    2004-01-01

    More and better machine learning tools are becoming available for landscape ecologists to aid in understanding species-environment relationships and to map probable species occurrence now and potentially into the future. To thal end, we evaluated three statistical models: Regression Tree Analybib (RTA), Bagging Trees (BT) and Random Forest (RF) for their utility in...

  13. The Performance Analysis of the Map-Aided Fuzzy Decision Tree Based on the Pedestrian Dead Reckoning Algorithm in an Indoor Environment

    Directory of Open Access Journals (Sweden)

    Kai-Wei Chiang

    2015-12-01

    Full Text Available Hardware sensors embedded in a smartphone allow the device to become an excellent mobile navigator. A smartphone is ideal for this task because its great international popularity has led to increased phone power and since most of the necessary infrastructure is already in place. However, using a smartphone for indoor pedestrian navigation can be problematic due to the low accuracy of sensors, imprecise predictability of pedestrian motion, and inaccessibility of the Global Navigation Satellite System (GNSS in some indoor environments. Pedestrian Dead Reckoning (PDR is one of the most common technologies used for pedestrian navigation, but in its present form, various errors tend to accumulate. This study introduces a fuzzy decision tree (FDT aided by map information to improve the accuracy and stability of PDR with less dependency on infrastructure. First, the map is quickly surveyed by the Indoor Mobile Mapping System (IMMS. Next, Bluetooth beacons are implemented to enable the initializing of any position. Finally, map-aided FDT can estimate navigation solutions in real time. The experiments were conducted in different fields using a variety of smartphones and users in order to verify stability. The contrast PDR system demonstrates low stability for each case without pre-calibration and post-processing, but the proposed low-complexity FDT algorithm shows good stability and accuracy under the same conditions.

  14. Relative performances of artificial neural network and regression mapping tools in evaluation of spinal loads and muscle forces during static lifting.

    Science.gov (United States)

    Arjmand, N; Ekrami, O; Shirazi-Adl, A; Plamondon, A; Parnianpour, M

    2013-05-31

    Two artificial neural networks (ANNs) are constructed, trained, and tested to map inputs of a complex trunk finite element (FE) model to its outputs for spinal loads and muscle forces. Five input variables (thorax flexion angle, load magnitude, its anterior and lateral positions, load handling technique, i.e., one- or two-handed static lifting) and four model outputs (L4-L5 and L5-S1 disc compression and anterior-posterior shear forces) for spinal loads and 76 model outputs (forces in individual trunk muscles) are considered. Moreover, full quadratic regression equations mapping input-outputs of the model developed here for muscle forces and previously for spine loads are used to compare the relative accuracy of these two mapping tools (ANN and regression equations). Results indicate that the ANNs are more accurate in mapping input-output relationships of the FE model (RMSE= 20.7 N for spinal loads and RMSE= 4.7 N for muscle forces) as compared to regression equations (RMSE= 120.4 N for spinal loads and RMSE=43.2 N for muscle forces). Quadratic regression equations map up to second order variations of outputs with inputs while ANNs capture higher order variations too. Despite satisfactory achievement in estimating overall muscle forces by the ANN, some inadequacies are noted including assigning force to antagonistic muscles with no activity in the optimization algorithm of the FE model or predicting slightly different forces in bilateral pair muscles in symmetric lifting activities. Using these user-friendly tools spine loads and trunk muscle forces during symmetric and asymmetric static lifts can be easily estimated. Copyright © 2013 Elsevier Ltd. All rights reserved.

  15. Energetic map

    International Nuclear Information System (INIS)

    2012-01-01

    This report explains the energetic map of Uruguay as well as the different systems that delimits political frontiers in the region. The electrical system importance is due to the electricity, oil and derived , natural gas, potential study, biofuels, wind and solar energy

  16. Necklace maps

    NARCIS (Netherlands)

    Speckmann, B.; Verbeek, K.A.B.

    2010-01-01

    Statistical data associated with geographic regions is nowadays globally available in large amounts and hence automated methods to visually display these data are in high demand. There are several well-established thematic map types for quantitative data on the ratio-scale associated with regions:

  17. Participatory maps

    DEFF Research Database (Denmark)

    Salovaara-Moring, Inka

    towards a new political ecology. This type of digital cartographies has been highlighted as the ‘processual turn’ in critical cartography, whereas in related computational journalism it can be seen as an interactive and iterative process of mapping complex and fragile ecological developments. This paper...

  18. Hazard Map for Autonomous Navigation

    DEFF Research Database (Denmark)

    Riis, Troels

    This dissertation describes the work performed in the area of using image analysis in the process of landing a spacecraft autonomously and safely on the surface of the Moon. This is suggested to be done using a Hazard Map. The correspondence problem between several Hazard Maps are investigated...

  19. Perform wordcount Map-Reduce Job in Single Node Apache Hadoop cluster and compress data using Lempel-Ziv-Oberhumer (LZO) algorithm

    OpenAIRE

    Mirajkar, Nandan; Bhujbal, Sandeep; Deshmukh, Aaradhana

    2013-01-01

    Applications like Yahoo, Facebook, Twitter have huge data which has to be stored and retrieved as per client access. This huge data storage requires huge database leading to increase in physical storage and becomes complex for analysis required in business growth. This storage capacity can be reduced and distributed processing of huge data can be done using Apache Hadoop which uses Map-reduce algorithm and combines the repeating data so that entire data is stored in reduced format. The paper ...

  20. Sentinel nodes are identifiable in formalin-fixed specimens after surgeon-performed ex vivo sentinel lymph node mapping in colorectal cancer.

    LENUS (Irish Health Repository)

    Smith, Fraser McLean

    2012-02-03

    BACKGROUND: In recent years, the technique of sentinel lymph node (SLN) mapping has been applied to colorectal cancer. One aim was to ultrastage patients who were deemed node negative by routine pathologic processing but who went on to develop systemic disease. Such a group may benefit from adjuvant chemotherapy. METHODS: With fully informed consent and ethical approval, 37 patients with primary colorectal cancer and 3 patients with large adenomas were prospectively mapped. Isosulfan blue dye (1 to 2 mL) was injected around tumors within 5 to 10 minutes of resection. After gentle massage to recreate in vivo lymph flow, specimens were placed directly into formalin. During routine pathologic analysis, all nodes were bivalved, and blue-staining nodes were noted. These later underwent multilevel step sectioning with hematoxylin and eosin and cytokeratin staining. RESULTS: SLNs were found in 39 of 40 patients (98% sensitivity), with an average of 4.1 SLNs per patient (range, 1-8). In 14 of 16 (88% specificity) patients with nodal metastases on routine reporting, SLN status was in accordance. Focused examination of SLNs identified occult tumor deposits in 6 (29%) of 21 node-negative patients. No metastatic cells were found in SLNs draining the three adenomas. CONCLUSIONS: The ability to identify SLNs after formalin fixation increases the ease and applicability of SLN mapping in colorectal cancer. Furthermore, the sensitivity and specificity of this simple ex vivo method for establishing regional lymph node status were directly comparable to those in previously published reports.

  1. MAPPING INNOVATION

    DEFF Research Database (Denmark)

    Thuesen, Christian Langhoff; Koch, Christian

    2011-01-01

    By adopting a theoretical framework from strategic niche management research (SNM) this paper presents an analysis of the innovation system of the Danish Construction industry. The analysis shows a multifaceted landscape of innovation around an existing regime, built around existing ways of working...... and developed over generations. The regime is challenged from various niches and the socio-technical landscape through trends as globalization. Three niches (Lean Construction, BIM and System Deliveries) are subject to a detailed analysis showing partly incompatible rationales and various degrees of innovation...... potential. The paper further discusses how existing policymaking operates in a number of tensions one being between government and governance. Based on the concepts from SNM the paper introduces an innovation map in order to support the development of meta-governance policymaking. By mapping some...

  2. Mapping filmmaking

    DEFF Research Database (Denmark)

    Gilje, Øystein; Frølunde, Lisbeth; Lindstrand, Fredrik

    2010-01-01

    This chapter concerns mapping patterns in regards to how young filmmakers (age 15 – 20) in the Scandinavian countries learn about filmmaking. To uncover the patterns, we present portraits of four young filmmakers who participated in the Scandinavian research project Making a filmmaker. The focus ...... is on their learning practices and how they create ‘learning paths’ in relation to resources in diverse learning contexts, whether formal, non-formal and informal contexts.......This chapter concerns mapping patterns in regards to how young filmmakers (age 15 – 20) in the Scandinavian countries learn about filmmaking. To uncover the patterns, we present portraits of four young filmmakers who participated in the Scandinavian research project Making a filmmaker. The focus...

  3. PERFORMANCE

    Directory of Open Access Journals (Sweden)

    M Cilli

    2014-10-01

    Full Text Available This study aimed to investigate the kinematic and kinetic changes when resistance is applied in horizontal and vertical directions, produced by using different percentages of body weight, caused by jumping movements during a dynamic warm-up. The group of subjects consisted of 35 voluntary male athletes (19 basketball and 16 volleyball players; age: 23.4 ± 1.4 years, training experience: 9.6 ± 2.7 years; height: 177.2 ± 5.7 cm, body weight: 69.9 ± 6.9 kg studying Physical Education, who had a jump training background and who were training for 2 hours, on 4 days in a week. A dynamic warm-up protocol containing seven specific resistance movements with specific resistance corresponding to different percentages of body weight (2%, 4%, 6%, 8%, 10% was applied randomly on non consecutive days. Effects of different warm-up protocols were assessed by pre-/post- exercise changes in jump height in the countermovement jump (CMJ and the squat jump (SJ measured using a force platform and changes in hip and knee joint angles at the end of the eccentric phase measured using a video camera. A significant increase in jump height was observed in the dynamic resistance warm-up conducted with different percentages of body weight (p 0.05. In jump movements before and after the warm-up, while no significant difference between the vertical ground reaction forces applied by athletes was observed (p>0.05, in some cases of resistance, a significant reduction was observed in hip and knee joint angles (p<0.05. The dynamic resistance warm-up method was found to cause changes in the kinematics of jumping movements, as well as an increase in jump height values. As a result, dynamic warm-up exercises could be applicable in cases of resistance corresponding to 6-10% of body weight applied in horizontal and vertical directions in order to increase the jump performance acutely.

  4. The homozygosity verification for doubled haploid Japanese ...

    African Journals Online (AJOL)

    ELOHO

    2012-09-18

    Sep 18, 2012 ... 2College of Animal Science and Technology, Northeast Agricultural University, Harbin ... homozygous at all loci tested, while, the rest 580 offspring were ... Additionally, the embryonic development and external morphology of ...

  5. Using the multiple regression analysis with respect to ANOVA and 3D mapping to model the actual performance of PEM (proton exchange membrane) fuel cell at various operating conditions

    International Nuclear Information System (INIS)

    Al-Hadeethi, Farqad; Al-Nimr, Moh'd; Al-Safadi, Mohammad

    2015-01-01

    The performance of PEM (proton exchange membrane) fuel cell was experimentally investigated at three temperatures (30, 50 and 70 °C), four flow rates (5, 10, 15 and 20 ml/min) and two flow patterns (co-current and counter current) in order to generate two correlations using multiple regression analysis with respect to ANOVA. Results revealed that increasing the temperature for co-current and counter current flow patterns will increase both hydrogen and oxygen diffusivities, water management and membrane conductivity. The derived mathematical correlations and three dimensional mapping (i.e. surface response) for the co-current and countercurrent flow patterns showed that there is a clear interaction among the various variables (temperatures and flow rates). - Highlights: • Generating mathematical correlations using multiple regression analysis with respect to ANOVA for the performance of the PEM fuel cell. • Using the 3D mapping to diagnose the optimum performance of the PEM fuel cell at the given operating conditions. • Results revealed that increasing the flow rate had direct influence on the consumption of oxygen. • Results assured that increasing the temperature in co-current and counter current flow patterns increases the performance of PEM fuel cell.

  6. Generating Multi-Destination Maps.

    Science.gov (United States)

    Zhang, Junsong; Fan, Jiepeng; Luo, Zhenshan

    2017-08-01

    Multi-destination maps are a kind of navigation maps aimed to guide visitors to multiple destinations within a region, which can be of great help to urban visitors. However, they have not been developed in the current online map service. To address this issue, we introduce a novel layout model designed especially for generating multi-destination maps, which considers the global and local layout of a multi-destination map. We model the layout problem as a graph drawing that satisfies a set of hard and soft constraints. In the global layout phase, we balance the scale factor between ROIs. In the local layout phase, we make all edges have good visibility and optimize the map layout to preserve the relative length and angle of roads. We also propose a perturbation-based optimization method to find an optimal layout in the complex solution space. The multi-destination maps generated by our system are potential feasible on the modern mobile devices and our result can show an overview and a detail view of the whole map at the same time. In addition, we perform a user study to evaluate the effectiveness of our method, and the results prove that the multi-destination maps achieve our goals well.

  7. Drawing Road Networks with Mental Maps.

    Science.gov (United States)

    Lin, Shih-Syun; Lin, Chao-Hung; Hu, Yan-Jhang; Lee, Tong-Yee

    2014-09-01

    Tourist and destination maps are thematic maps designed to represent specific themes in maps. The road network topologies in these maps are generally more important than the geometric accuracy of roads. A road network warping method is proposed to facilitate map generation and improve theme representation in maps. The basic idea is deforming a road network to meet a user-specified mental map while an optimization process is performed to propagate distortions originating from road network warping. To generate a map, the proposed method includes algorithms for estimating road significance and for deforming a road network according to various geometric and aesthetic constraints. The proposed method can produce an iconic mark of a theme from a road network and meet a user-specified mental map. Therefore, the resulting map can serve as a tourist or destination map that not only provides visual aids for route planning and navigation tasks, but also visually emphasizes the presentation of a theme in a map for the purpose of advertising. In the experiments, the demonstrations of map generations show that our method enables map generation systems to generate deformed tourist and destination maps efficiently.

  8. Mapping Resilience

    DEFF Research Database (Denmark)

    Carruth, Susan

    2015-01-01

    by planners when aiming to construct resilient energy plans. It concludes that a graphical language has the potential to be a significant tool, flexibly facilitating cross-disciplinary communication and decision-making, while emphasising that its role is to support imaginative, resilient planning rather than...... the relationship between resilience and energy planning, suggesting that planning in, and with, time is a core necessity in this domain. It then reviews four examples of graphically mapping with time, highlighting some of the key challenges, before tentatively proposing a graphical language to be employed...

  9. Mapping of

    Directory of Open Access Journals (Sweden)

    Sayed M. Arafat

    2014-06-01

    Full Text Available Land cover map of North Sinai was produced based on the FAO-Land Cover Classification System (LCCS of 2004. The standard FAO classification scheme provides a standardized system of classification that can be used to analyze spatial and temporal land cover variability in the study area. This approach also has the advantage of facilitating the integration of Sinai land cover mapping products to be included with the regional and global land cover datasets. The total study area is covering a total area of 20,310.4 km2 (203,104 hectare. The landscape classification was based on SPOT4 data acquired in 2011 using combined multispectral bands of 20 m spatial resolution. Geographic Information System (GIS was used to manipulate the attributed layers of classification in order to reach the maximum possible accuracy. GIS was also used to include all necessary information. The identified vegetative land cover classes of the study area are irrigated herbaceous crops, irrigated tree crops and rain fed tree crops. The non-vegetated land covers in the study area include bare rock, bare soils (stony, very stony and salt crusts, loose and shifting sands and sand dunes. The water bodies were classified as artificial perennial water bodies (fish ponds and irrigated canals and natural perennial water bodies as lakes (standing. The artificial surfaces include linear and non-linear features.

  10. An integrated high-performance beam optics-nuclear processes framework with hybrid transfer map-Monte Carlo particle transport and optimization

    Energy Technology Data Exchange (ETDEWEB)

    Bandura, L., E-mail: bandura@msu.ed [Argonne National Laboratory, Argonne, IL 60439 (United States); Erdelyi, B. [Argonne National Laboratory, Argonne, IL 60439 (United States); Northern Illinois University, DeKalb, IL 60115 (United States); Nolen, J. [Argonne National Laboratory, Argonne, IL 60439 (United States)

    2010-12-01

    An integrated beam optics-nuclear processes framework is essential for accurate simulation of fragment separator beam dynamics. The code COSY INFINITY provides powerful differential algebraic methods for modeling and beam dynamics simulations in absence of beam-material interactions. However, these interactions are key for accurately simulating the dynamics of heavy ion fragmentation and fission. We have developed an extended version of the code that includes these interactions, and a set of new tools that allow efficient and accurate particle transport: by transfer map in vacuum and by Monte Carlo methods in materials. The new framework is presented, along with several examples from a preliminary layout of a fragment separator for a facility for rare isotope beams.

  11. An integrated high-performance beam optics-nuclear processes framework with hybrid transfer map-Monte Carlo particle transport and optimization

    International Nuclear Information System (INIS)

    Bandura, L.; Erdelyi, B.; Nolen, J.

    2010-01-01

    An integrated beam optics-nuclear processes framework is essential for accurate simulation of fragment separator beam dynamics. The code COSY INFINITY provides powerful differential algebraic methods for modeling and beam dynamics simulations in absence of beam-material interactions. However, these interactions are key for accurately simulating the dynamics of heavy ion fragmentation and fission. We have developed an extended version of the code that includes these interactions, and a set of new tools that allow efficient and accurate particle transport: by transfer map in vacuum and by Monte Carlo methods in materials. The new framework is presented, along with several examples from a preliminary layout of a fragment separator for a facility for rare isotope beams.

  12. eMAPS

    CERN Document Server

    Human Resources Department

    2005-01-01

    Starting with the 2005 performance appraisal and advancement exercise (MAPS), the paper version of the annual appraisal report has been replaced by an electronic EDH version - eMAPS (see Weekly Bulletin 48/2004). As announced in Weekly Bulletin 2/2005, information sessions to explain the features of eMAPS using EDH have been arranged as follows: 18 January 2005: Main Auditorium (500-1-001) from 14:00 to 15:30. 20 January 2005: AB Auditorium II (864-1-D02) from 14:00 to 15:30. 24 January 2005: AT Auditorium (30-7-018) from 10:00 to 11:30. The changeover to an electronic appraisal report is designed to reduce the administrative workload involving, e.g. photocopying, tracing and filing paper copies, while allowing staff members and their hierarchy access to the report form at the appropriate times. There is no change in the procedure for the annual interview and the advancement exercise, though Administrative Circular No 26 (Rev. 5) has been updated to take account of the introduction of eMAPS. The content...

  13. How to perform RT-qPCR accurately in plant species? A case study on flower colour gene expression in an azalea (Rhododendron simsii hybrids) mapping population.

    Science.gov (United States)

    De Keyser, Ellen; Desmet, Laurence; Van Bockstaele, Erik; De Riek, Jan

    2013-06-24

    Flower colour variation is one of the most crucial selection criteria in the breeding of a flowering pot plant, as is also the case for azalea (Rhododendron simsii hybrids). Flavonoid biosynthesis was studied intensively in several species. In azalea, flower colour can be described by means of a 3-gene model. However, this model does not clarify pink-coloration. The last decade gene expression studies have been implemented widely for studying flower colour. However, the methods used were often only semi-quantitative or quantification was not done according to the MIQE-guidelines. We aimed to develop an accurate protocol for RT-qPCR and to validate the protocol to study flower colour in an azalea mapping population. An accurate RT-qPCR protocol had to be established. RNA quality was evaluated in a combined approach by means of different techniques e.g. SPUD-assay and Experion-analysis. We demonstrated the importance of testing noRT-samples for all genes under study to detect contaminating DNA. In spite of the limited sequence information available, we prepared a set of 11 reference genes which was validated in flower petals; a combination of three reference genes was most optimal. Finally we also used plasmids for the construction of standard curves. This allowed us to calculate gene-specific PCR efficiencies for every gene to assure an accurate quantification. The validity of the protocol was demonstrated by means of the study of six genes of the flavonoid biosynthesis pathway. No correlations were found between flower colour and the individual expression profiles. However, the combination of early pathway genes (CHS, F3H, F3'H and FLS) is clearly related to co-pigmentation with flavonols. The late pathway genes DFR and ANS are to a minor extent involved in differentiating between coloured and white flowers. Concerning pink coloration, we could demonstrate that the lower intensity in this type of flowers is correlated to the expression of F3'H. Currently in plant

  14. Acid Deposition Maps in Spain

    International Nuclear Information System (INIS)

    Artinano, B.; Cabal, H.; Garcia, C.

    1998-01-01

    Animal and monthly deposition velocity and total sulfur deposition maps have been performed for the peninsular Spain for 1992 by using the inferential method. To do this, updated databases with high space and time resolution, for land uses (CORINE) and meteorological information from analysis modelling for the same year, have been utilized. The final result are deposition maps in a 5x5 Km 2 grid which allow to assess the methodology used in Europe to obtain the maps of excedances over the critical loads of pollutants. (Author) 32 refs

  15. NeatMap--non-clustering heat map alternatives in R.

    Science.gov (United States)

    Rajaram, Satwik; Oono, Yoshi

    2010-01-22

    The clustered heat map is the most popular means of visualizing genomic data. It compactly displays a large amount of data in an intuitive format that facilitates the detection of hidden structures and relations in the data. However, it is hampered by its use of cluster analysis which does not always respect the intrinsic relations in the data, often requiring non-standardized reordering of rows/columns to be performed post-clustering. This sometimes leads to uninformative and/or misleading conclusions. Often it is more informative to use dimension-reduction algorithms (such as Principal Component Analysis and Multi-Dimensional Scaling) which respect the topology inherent in the data. Yet, despite their proven utility in the analysis of biological data, they are not as widely used. This is at least partially due to the lack of user-friendly visualization methods with the visceral impact of the heat map. NeatMap is an R package designed to meet this need. NeatMap offers a variety of novel plots (in 2 and 3 dimensions) to be used in conjunction with these dimension-reduction techniques. Like the heat map, but unlike traditional displays of such results, it allows the entire dataset to be displayed while visualizing relations between elements. It also allows superimposition of cluster analysis results for mutual validation. NeatMap is shown to be more informative than the traditional heat map with the help of two well-known microarray datasets. NeatMap thus preserves many of the strengths of the clustered heat map while addressing some of its deficiencies. It is hoped that NeatMap will spur the adoption of non-clustering dimension-reduction algorithms.

  16. Human Mind Maps

    Science.gov (United States)

    Glass, Tom

    2016-01-01

    When students generate mind maps, or concept maps, the maps are usually on paper, computer screens, or a blackboard. Human Mind Maps require few resources and little preparation. The main requirements are space where students can move around and a little creativity and imagination. Mind maps can be used for a variety of purposes, and Human Mind…

  17. Effects of Concept-Mapping-Based Interactive E-Books on Active and Reflective-Style Students' Learning Performances in Junior High School Law Courses

    Science.gov (United States)

    Hwang, Gwo-Jen; Sung, Han-Yu; Chang, Hsuan

    2017-01-01

    Researchers have pointed out that interactive e-books have rich content and interactive features which can promote students' learning interest. However, researchers have also indicated the need to integrate effective learning supports or tools to help students organize what they have learned so as to increase their learning performance, in…

  18. Explorative analysis of 2D color maps

    OpenAIRE

    Steiger, Martin; Bernard, Jürgen; Thum, Simon; Mittelstädt, Sebastian; Hutter, Marco; Keim, Daniel A.; Kohlhammer, Jörn

    2015-01-01

    Color is one of the most important visual variables in information visualization. In many cases, two-dimensional information can be color-coded based on a 2D color map. A variety of color maps as well as a number of quality criteria for the use of color have been presented. The choice of the best color map depends on the analytical task users intend to perform and the design space in choosing an appropriate 2D color map is large. In this paper, we present the ColorMap-Explorer, a visual-inter...

  19. Maps & minds : mapping through the ages

    Science.gov (United States)

    ,

    1984-01-01

    Throughout time, maps have expressed our understanding of our world. Human affairs have been influenced strongly by the quality of maps available to us at the major turning points in our history. "Maps & Minds" traces the ebb and flow of a few central ideas in the mainstream of mapping. Our expanding knowledge of our cosmic neighborhood stems largely from a small number of simple but grand ideas, vigorously pursued.

  20. Demonstrating the effectiveness of body armour: a pilot prospective computerised surface wound mapping trial performed at the Role 3 hospital in Afghanistan.

    Science.gov (United States)

    Breeze, Johno; Allanson-Bailey, L S; Hepper, A E; Midwinter, M J

    2015-03-01

    Modern body armour clearly reduces injury incidence and severity, but evidence to actually objectively demonstrate this effect is scarce. Although the Joint Theatre Trauma Registry (JTTR) alone cannot relate injury pattern to body armour coverage, the addition of computerised Surface Wound Mapping (SWM) may enable this utility. Surface wound locations of all UK and NATO coalition soldiers, Afghan National Army and Police and local nationals injured by explosively propelled fragments and treated in the Role 3 UK-led Field Hospital in Camp Bastion, Afghanistan, between 8 July and 20 October 2012 were prospectively recorded. The Abbreviated Injury Scores (AIS) and relative risk of casualties sustaining injuries under a type of body armour were compared with those that did not wear that armour. Casualties wearing a combat helmet were 2.7 times less likely to sustain a fragmentation wound to the head than those that were unprotected (mean AIS of 2.9 compared with 4.1). Casualties wearing a body armour vest were 4.1 times less likely to sustain a fragmentation wound to the chest or abdomen than those that were unprotected (mean AIS of 2.9 compared with 3.9). Casualties wearing pelvic protection were 10 times less likely to sustain a fragmentation wound to the pelvis compared with those that were unprotected (mean AIS of 3.4 compared with 3.9). Computerised SWM has objectively demonstrated the ability of body armour worn on current operations in Afghanistan to reduce wound incidence and severity. We recognise this technique is limited in that it only records the surface wound location and may be specific to this conflict. However, gathering electronic SWM at the same time as recording injuries for the JTTR was simple, required little extra time and therefore we would recommend its collection during future conflicts. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  1. Lunar Map Catalog

    Data.gov (United States)

    National Aeronautics and Space Administration — The Lunar Map Catalog includes various maps of the moon's surface, including Apollo landing sites; earthside, farside, and polar charts; photography index maps; zone...

  2. Baby Brain Map

    Science.gov (United States)

    ... a Member Home Resources & Services Professional Resource Baby Brain Map Mar 17, 2016 The Brain Map was adapted in 2006 by ZERO TO ... supports Adobe Flash Player. To view the Baby Brain Map, please visit this page on a browser ...

  3. Snapshots for Semantic Maps

    National Research Council Canada - National Science Library

    Nielsen, Curtis W; Ricks, Bob; Goodrich, Michael A; Bruemmer, David; Few, Doug; Walton, Miles

    2004-01-01

    .... Semantic maps are a relatively new approach to information presentation. Semantic maps provide more detail about an environment than typical maps because they are augmented by icons or symbols that provide meaning for places or objects of interest...

  4. Concept Mapping zur Unterstützung der differentialdiagnostischen Hypothesenbildung im fallbasierten Online-Lernsystem CASUS: Qualitative Verbesserung der Diagnosefindung durch ICD-10 Kodierung [Concept mapping for supporting the differential diagnostic generation of hypotheses in the case-based online learning system CASUS: Qualitative improvement of dagnostic performance through ICD-10 coding

    Directory of Open Access Journals (Sweden)

    Kernt, Marcus

    2008-08-01

    Full Text Available [english] Introduction: Concept mapping tools have long been established in medical education as an aid for visualizing learning processes in computer-based programs. The case-based learning system CASUS with its mapping tool for visualizing the differential diagnostic reasoning process is an example. It was shown that such tools are well accepted by users and lead to an increased number of diagnostic hypotheses being visualized as maps. However, there is scarce evidence on the quality of user-generated diagnostic hypotheses. This study examines the quality of diagnostic hypotheses obtained with CASUS and whether the quality can be improved through ICD-10 coding as compared with an expert’s solution. Methods: We randomized 192 third-year medical students at the University of Munich into two groups. The students worked in groups of two on one computer. Group A was asked to code their diagnostic hypotheses with an ICD-10 coding browser before entering them into the mapping tool. Group B generated their hypotheses without prior ICD-10 coding. The differential diagnostic reasoning visualizations were analyzed quantitatively and qualitatively. An expert solution was used as reference. Results: Eighty-seven differential diagnoses were evaluated. Group A, using ICD-10 coding, made the correct and precise diagnosis of malaria tropica significantly more often than Group B (p < 0.05. For additional alternative diagnostic hypotheses, no quantitative or qualitative differences were detected. Conclusions: ICD-10 coding in connection with a mapping tool supporting the diagnostic reasoning process improved the accuracy of diagnostic performance in third-year medical students in the case of malaria tropica. [german] Einleitung: Der Einsatz von Concept-Mapping-Tools in computergestützten Lernprogrammen ist in der medizinischen Ausbildung etabliert: Es konnte gezeigt werden, dass diese Werkzeuge zur Visualisierung von Differentialdiagnosen vom Anwender

  5. Mapping the brain

    International Nuclear Information System (INIS)

    Begley, S.; Wright, L.; Church, V.; Hager, M.

    1992-01-01

    With powerful new technologies such as positron tomography and superconducting quantum interference device that peer through the skull and see the brain at work, neuroscientists seek the wellsprings of thoughts and emotions, the genesis of intelligence and language. A functional map of the brain is thus obtained and its challenge is to move beyond brain structure to create a detailed diagram of which part do what. For that the brain's cartographers rely on a variety of technologies such as positron tomography and superconducting quantum interference devices. Their performances and uses are briefly reviewed. ills

  6. Between Maps and Territories

    DEFF Research Database (Denmark)

    Holmboe, Rasmus; Stricker, Jan Høgh

    2016-01-01

    This audio paper departs from an artwork made by Andreas Führer called The Map is Not The Territory D’Or; a score for a soundwalk in the town of Roskilde, Denmark. The basic sound materials used in the audio paper are 1) an interview in Danish with the artist, 2) a voice over of a theoretical text...... in English, and 3) recordings from performances of the piece, including walking, breathing exercises, and the sounds of ventilation systems and other environmental sound. By mingling these different materials, and by using ‘map’ and ‘territory’ as metaphors, the paper complicates issues of representation...

  7. Mapping the Heart

    Science.gov (United States)

    Hulse, Grace

    2012-01-01

    In this article, the author describes how her fourth graders made ceramic heart maps. The impetus for this project came from reading "My Map Book" by Sara Fanelli. This book is a collection of quirky, hand-drawn and collaged maps that diagram a child's world. There are maps of her stomach, her day, her family, and her heart, among others. The…

  8. USGS Map Indices Overlay Map Service from The National Map

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The USGS Map Indices service from The National Map (TNM) consists of 1x1 Degree, 30x60 Minute (100K), 15 Minute (63K), 7.5 Minute (24K), and 3.75 Minute grid...

  9. Mapping lexical-semantic networks and determining hemispheric language dominance: Do task design, sex, age, and language performance make a difference?

    Science.gov (United States)

    Chang, Yu-Hsuan A; Javadi, Sogol S; Bahrami, Naeim; Uttarwar, Vedang S; Reyes, Anny; McDonald, Carrie R

    2018-04-01

    Blocked and event-related fMRI designs are both commonly used to localize language networks and determine hemispheric dominance in research and clinical settings. We compared activation profiles on a semantic monitoring task using one of the two designs in a total of 43 healthy individual to determine whether task design or subject-specific factors (i.e., age, sex, or language performance) influence activation patterns. We found high concordance between the two designs within core language regions, including the inferior frontal, posterior temporal, and basal temporal region. However, differences emerged within inferior parietal cortex. Subject-specific factors did not influence activation patterns, nor did they interact with task design. These results suggest that despite high concordance within perisylvian regions that are robust to subject-specific factors, methodological differences between blocked and event-related designs may contribute to parietal activations. These findings provide important information for researchers incorporating fMRI results into meta-analytic studies, as well as for clinicians using fMRI to guide pre-surgical planning. Copyright © 2018 Elsevier Inc. All rights reserved.

  10. 7. Annex II: Maps

    OpenAIRE

    Aeberli, Annina

    2012-01-01

    Map 1: States of South Sudan UN OCHA (2012) Republic of South Sudan – States, as of 15 July 2012, Reliefweb http://reliefweb.int/map/south-sudan-republic/republic-south-sudan-states-15-july-2012-reference-map, accessed 31 July 2012. Map 2: Counties of South Sudan UN OCHA (2012) Republic of South Sudan – Counties, as of 16 July 2012, Reliefweb http://reliefweb.int/map/south-sudan-republic/republic-south-sudan-counties-16-july-2012-reference-map, accessed 31 July 2012. Map 3: Eastern Equato...

  11. Applicability of vulnerability maps

    International Nuclear Information System (INIS)

    Andersen, L.J.; Gosk, E.

    1989-01-01

    A number of aspects to vulnerability maps are discussed: the vulnerability concept, mapping purposes, possible users, and applicability of vulnerability maps. Problems associated with general-type vulnerability mapping, including large-scale maps, universal pollutant, and universal pollution scenario are also discussed. An alternative approach to vulnerability assessment - specific vulnerability mapping for limited areas, specific pollutant, and predefined pollution scenario - is suggested. A simplification of the vulnerability concept is proposed in order to make vulnerability mapping more objective and by this means more comparable. An extension of the vulnerability concept to the rest of the hydrogeological cycle (lakes, rivers, and the sea) is proposed. Some recommendations regarding future activities are given

  12. Differential maps, difference maps, interpolated maps, and long term prediction

    International Nuclear Information System (INIS)

    Talman, R.

    1988-06-01

    Mapping techniques may be thought to be attractive for the long term prediction of motion in accelerators, especially because a simple map can approximately represent an arbitrarily complicated lattice. The intention of this paper is to develop prejudices as to the validity of such methods by applying them to a simple, exactly solveable, example. It is shown that a numerical interpolation map, such as can be generated in the accelerator tracking program TEAPOT, predicts the evolution more accurately than an analytically derived differential map of the same order. Even so, in the presence of ''appreciable'' nonlinearity, it is shown to be impractical to achieve ''accurate'' prediction beyond some hundreds of cycles of oscillation. This suggests that the value of nonlinear maps is restricted to the parameterization of only the ''leading'' deviation from linearity. 41 refs., 6 figs

  13. Identification of genomic regions associated with phenotypic variation between dog breeds using selection mapping.

    Directory of Open Access Journals (Sweden)

    Amaury Vaysse

    2011-10-01

    Full Text Available The extraordinary phenotypic diversity of dog breeds has been sculpted by a unique population history accompanied by selection for novel and desirable traits. Here we perform a comprehensive analysis using multiple test statistics to identify regions under selection in 509 dogs from 46 diverse breeds using a newly developed high-density genotyping array consisting of >170,000 evenly spaced SNPs. We first identify 44 genomic regions exhibiting extreme differentiation across multiple breeds. Genetic variation in these regions correlates with variation in several phenotypic traits that vary between breeds, and we identify novel associations with both morphological and behavioral traits. We next scan the genome for signatures of selective sweeps in single breeds, characterized by long regions of reduced heterozygosity and fixation of extended haplotypes. These scans identify hundreds of regions, including 22 blocks of homozygosity longer than one megabase in certain breeds. Candidate selection loci are strongly enriched for developmental genes. We chose one highly differentiated region, associated with body size and ear morphology, and characterized it using high-throughput sequencing to provide a list of variants that may directly affect these traits. This study provides a catalogue of genomic regions showing extreme reduction in genetic variation or population differentiation in dogs, including many linked to phenotypic variation. The many blocks of reduced haplotype diversity observed across the genome in dog breeds are the result of both selection and genetic drift, but extended blocks of homozygosity on a megabase scale appear to be best explained by selection. Further elucidation of the variants under selection will help to uncover the genetic basis of complex traits and disease.

  14. Geologic mapping procedure: Final draft

    International Nuclear Information System (INIS)

    1987-09-01

    Geologic mapping will provide a baseline record of the subsurface geology in the shafts and drifts of the Exploratory Shaft Facility (ESF). This information will be essential in confirming the specific repository horizon, selecting representative locations for the in situ tests, providing information for construction and decommissioning seal designs, documenting the excavation effects, and in providing information for performance assessment, which relates to the ultimate suitability of the site as a nuclear waste repository. Geologic mapping will be undertaken on the walls and roof, and locally on the floor within the completed At-Depth Facility (ADF) and on the walls of the two access shafts. Periodic mapping of the exposed face may be conducted during construction of the ADF. The mapping will be oriented toward the collection and presentation of geologic information in an engineering format and the portrayal of detailed stratigraphic information which may be useful in confirmation of drillhole data collected as part of the surface-based testing program. Geologic mapping can be considered as a predictive tool as well as a means of checking design assumptions. This document provides a description of the required procedures for geologic mapping for the ESF. Included in this procedure is information that qualified technical personnel can use to collect the required types of geologic descriptions, at the appropriate level of detail. 5 refs., 3 figs., 1 tab

  15. VEGETATION MAPPING IN WETLANDS

    Directory of Open Access Journals (Sweden)

    F. PEDROTTI

    2004-01-01

    Full Text Available The current work examines the main aspects of wetland vegetation mapping, which can be summarized as analysis of the ecological-vegetational (ecotone gradients; vegetation complexes; relationships between vegetation distribution and geomorphology; vegetation of the hydrographic basin lo which the wetland in question belongs; vegetation monitoring with help of four vegetation maps: phytosociological map of the real and potential vegetation, map of vegetation dynamical tendencies, map of vegetation series.

  16. Endpoint distinctiveness facilitates analogical mapping in pigeons.

    Science.gov (United States)

    Hagmann, Carl Erick; Cook, Robert G

    2015-03-01

    Analogical thinking necessitates mapping shared relations across two separate domains. We investigated whether pigeons could learn faster with ordinal mapping of relations across two physical dimensions (circle size & choice spatial position) relative to random mapping of these relations. Pigeons were trained to relate six circular samples of different sizes to horizontally positioned choice locations in a six alternative matching-to-sample task. Three pigeons were trained in a mapped condition in which circle size mapped directly onto choice spatial position. Three other pigeons were trained in a random condition in which the relations between size and choice position were arbitrarily assigned. The mapped group showed an advantage over the random group in acquiring this task. In a subsequent second phase, relations between the dimensions were ordinally reversed for the mapped group and re-randomized for the random group. There was no difference in how quickly matching accuracy re-emerged in the two groups, although the mapped group eventually performed more accurately. Analyses suggested this mapped advantage was likely due to endpoint distinctiveness and the benefits of proximity errors during choice responding rather than a conceptual or relational advantage attributable to the common or ordinal mapping of the two dimensions. This potential difficulty in mapping relations across dimensions may limit the pigeons' capacity for more advanced types of analogical reasoning. This article is part of a Special Issue entitled: Tribute to Tom Zentall. Copyright © 2014 Elsevier B.V. All rights reserved.

  17. Endpoint Distinctiveness Facilitates Analogical Mapping in Pigeons

    Science.gov (United States)

    Hagmann, Carl Erick; Cook, Robert G.

    2015-01-01

    Analogical thinking necessitates mapping shared relations across two separate domains. We investigated whether pigeons could learn faster with ordinal mapping of relations across two physical dimensions (circle size & choice spatial position) relative to random mapping of these relations. Pigeons were trained to relate six circular samples of different sizes to horizontally positioned choice locations in a six alternative matching-to-sample task. Three pigeons were trained in a mapped condition in which circle size mapped directly onto choice spatial position. Three other pigeons were trained in a random condition in which the relations between size and choice position were arbitrarily assigned. The mapped group showed an advantage over the random group in acquiring this task. In a subsequent second phase, reassignment, relations between the dimensions were ordinally reversed for the mapped group and re-randomized for the random group. There was no difference in how quickly matching accuracy re-emerged in the two groups, although the mapped group eventually performed more accurately. Analyses suggested this mapped advantage was likely due endpoint distinctiveness and the benefits of proximity errors during choice responding rather than a conceptual or relational advantage attributable to the common or ordinal map of the two dimensions. This potential difficulty in mapping relations across dimensions may limit the pigeons’ capacity for more advanced types of analogical reasoning. PMID:25447511

  18. Growth performance, meat quality traits, and genetic mapping of quantitative trait loci in 3 generations of Japanese quail populations (Coturnix japonica).

    Science.gov (United States)

    Tavaniello, S; Maiorano, G; Siwek, M; Knaga, S; Witkowski, A; Di Memmo, D; Bednarczyk, M

    2014-08-01

    The current research was conducted to compare growth, carcass traits, pH, intramuscular collagen (IMC) properties, and genetic bases of IMC and carcasses (breast-muscle weight) of different lines and generations of adult males and females of Japanese quail (Coturnix japonica). Forty-four quails (generation F0), 22 Pharaoh (F-33) meat-type males and 22 Standard (S-22) laying-type females, were crossed to produce the F1 hybrids generation. The F2 generation was created by mating one F1 male with one F1 female, full siblings. The birds, randomly chosen from F0 (22 males and 22 females), F1 (22 males and 22 females), and F2 (84 males and 152 females) were raised to 20 wk of age in collective cages. Quails were fed ad libitum commercial diets. At slaughter, all birds were individually weighed (after a fasting period of 12 h) and dressing yield (without giblets) was calculated. The carcasses were then dissected. Genomic DNA was extracted from all of the blood, and 30 microsatellite markers located on 2 quail chromosomes were genotyped. The F -: 33 quails had higher in vivo and postmortem performances and a higher abdominal fat percentage than those of the egg line. Meat from S -: 22 quails had a slower collagen maturation (hydroxylysylpyridinoline crosslink/collagen) and a higher ultimate pH. The F1 and F2 generations showed an evident sexual dimorphism, and an additional effect could be due to hybrid heterosis evident in F2. Meat from quails of F1 and F2 generations had a lower IMC amount with a higher degree of collagen maturation compared with parental lines. Two statistically significant QTL have been detected on quail chromosome 2 (CJA02): a QTL with an additive effect (0.50) for IMC in the marker bracket GUJ0037 and GUJ0093; a second QTL with additive (1.32) and dominant (1.91) effects for breast-muscle weight in the marker bracket GUJ0084 and GUJ0073. To our knowledge, this is the first report of a QTL associated with breast-muscle weight and IMC in quail and

  19. Expanding Thurston maps

    CERN Document Server

    Bonk, Mario

    2017-01-01

    This monograph is devoted to the study of the dynamics of expanding Thurston maps under iteration. A Thurston map is a branched covering map on a two-dimensional topological sphere such that each critical point of the map has a finite orbit under iteration. It is called expanding if, roughly speaking, preimages of a fine open cover of the underlying sphere under iterates of the map become finer and finer as the order of the iterate increases. Every expanding Thurston map gives rise to a fractal space, called its visual sphere. Many dynamical properties of the map are encoded in the geometry of this visual sphere. For example, an expanding Thurston map is topologically conjugate to a rational map if and only if its visual sphere is quasisymmetrically equivalent to the Riemann sphere. This relation between dynamics and fractal geometry is the main focus for the investigations in this work.

  20. Concept mapping instrumental support for problem solving

    NARCIS (Netherlands)

    Stoyanov, S.; Stoyanov, Slavi; Kommers, Petrus A.M.

    2008-01-01

    The main theoretical position of this paper is that it is the explicit problem-solving support in concept mapping software that produces a stronger effect in problem-solving performance than the implicit support afforded by the graphical functionality of concept mapping software. Explicit

  1. A Semantic Map for Evaluating Creativity

    NARCIS (Netherlands)

    van der Velde, Frank; van der Velde, Frank; Wolf, Roger A.; Schmettow, Martin; Nazareth, Deniece; Toivonen, Hannu; Colton, Simon; Cook, Michael; Ventura, Dan

    2015-01-01

    We present a semantic map of words related with creativity. The aim is to empirically derive terms which can be used to rate processes or products of computational creativity. The words in the map are based on association studies performed by human subjects and augmented with words derived from the

  2. Mapping in the cloud

    CERN Document Server

    Peterson, Michael P

    2014-01-01

    This engaging text provides a solid introduction to mapmaking in the era of cloud computing. It takes students through both the concepts and technology of modern cartography, geographic information systems (GIS), and Web-based mapping. Conceptual chapters delve into the meaning of maps and how they are developed, covering such topics as map layers, GIS tools, mobile mapping, and map animation. Methods chapters take a learn-by-doing approach to help students master application programming interfaces and build other technical skills for creating maps and making them available on the Internet. Th

  3. Mapping with Drupal

    CERN Document Server

    Palazzolo, Alan

    2011-01-01

    Build beautiful interactive maps on your Drupal website, and tell engaging visual stories with your data. This concise guide shows you how to create custom geographical maps from top to bottom, using Drupal 7 tools and out-of-the-box modules. You'll learn how mapping works in Drupal, with examples on how to use intuitive interfaces to map local events, businesses, groups, and other custom data. Although building maps with Drupal can be tricky, this book helps you navigate the system's complexities for creating sophisticated maps that match your site design. Get the knowledge and tools you ne

  4. Meso(topoclimatic maps and mapping

    Directory of Open Access Journals (Sweden)

    Ladislav Plánka

    2007-06-01

    Full Text Available The atmospheric characteristics can be studied from many points of view, most often we talk about time and spatial standpoint. Application of time standpoint leads either to different kinds of the synoptic and prognostic maps production, which presents actual state of atmosphere in short time section in the past or in the near future or to the climatic maps production which presents longterm weather regime. Spatial standpoint then differs map works according to natural phenomenon proportions, whereas the scale of their graphic presentation can be different. It depends on production purpose of each work.In the paper there are analysed methods of mapping and climatic maps production, which display longterm regime of chosen atmospheric features. These athmosphere features are formed in interaction with land surface and also have direct influence on people and their activities throughout the country. At the same time they’re influenced by anthropogenic intervention to the landscape.

  5. Data Assimilation with Optimal Maps

    Science.gov (United States)

    El Moselhy, T.; Marzouk, Y.

    2012-12-01

    Tarek El Moselhy and Youssef Marzouk Massachusetts Institute of Technology We present a new approach to Bayesian inference that entirely avoids Markov chain simulation and sequential importance resampling, by constructing a map that pushes forward the prior measure to the posterior measure. Existence and uniqueness of a suitable measure-preserving map is established by formulating the problem in the context of optimal transport theory. The map is written as a multivariate polynomial expansion and computed efficiently through the solution of a stochastic optimization problem. While our previous work [1] focused on static Bayesian inference problems, we now extend the map-based approach to sequential data assimilation, i.e., nonlinear filtering and smoothing. One scheme involves pushing forward a fixed reference measure to each filtered state distribution, while an alternative scheme computes maps that push forward the filtering distribution from one stage to the other. We compare the performance of these schemes and extend the former to problems of smoothing, using a map implementation of the forward-backward smoothing formula. Advantages of a map-based representation of the filtering and smoothing distributions include analytical expressions for posterior moments and the ability to generate arbitrary numbers of independent uniformly-weighted posterior samples without additional evaluations of the dynamical model. Perhaps the main advantage, however, is that the map approach inherently avoids issues of sample impoverishment, since it explicitly represents the posterior as the pushforward of a reference measure, rather than with a particular set of samples. The computational complexity of our algorithm is comparable to state-of-the-art particle filters. Moreover, the accuracy of the approach is controlled via the convergence criterion of the underlying optimization problem. We demonstrate the efficiency and accuracy of the map approach via data assimilation in

  6. A Map Enters the Conversation

    DEFF Research Database (Denmark)

    Munk, Anders Kristian

    Over the past decade STS scholars have been engaged in a continuous dialogue about the performativity of their methods and the interventions of their research practices. A frequently posed question is how STS can make a difference to its fields of study, what John Law has called its different...... 'modes of mattering'. In this paper I explore what difference digital cartography can make to STS practice. I draw on three examples from my own work where digitally mediated maps have entered the conversation and made critical, often surprising, differences to the research process. In my first example...... the map is brought along as an ethnographic device on a piece of fieldwork, in my second example it serves as the central collaborative object in a participatory design project, and in my third example the map becomes the object of contestation as it finds itself centre stage in the controversy...

  7. Active Fire Mapping Program

    Science.gov (United States)

    Active Fire Mapping Program Current Large Incidents (Home) New Large Incidents Fire Detection Maps MODIS Satellite Imagery VIIRS Satellite Imagery Fire Detection GIS Data Fire Data in Google Earth ...

  8. Using maps in genealogy

    Science.gov (United States)

    ,

    2002-01-01

    In genealogical research, maps can provide clues to where our ancestors may have lived and where to look for written records about them. Beginners should master basic genealogical research techniques before starting to use topographic maps.

  9. NGS Survey Control Map

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The NGS Survey Control Map provides a map of the US which allows you to find and display geodetic survey control points stored in the database of the National...

  10. National Pipeline Mapping System

    Data.gov (United States)

    Department of Transportation — The NPMS Public Map Viewer allows the general public to view maps of transmission pipelines, LNG plants, and breakout tanks in one selected county. Distribution and...

  11. NAIP Status Maps Gallery

    Data.gov (United States)

    Farm Service Agency, Department of Agriculture — NAIP Status Maps Gallery. These maps illustrate what aerial imagery collection is planned, whats been collected, when it is available and how it is available. These...

  12. Mapping Medicare Disparities Tool

    Data.gov (United States)

    U.S. Department of Health & Human Services — The CMS Office of Minority Health has designed an interactive map, the Mapping Medicare Disparities Tool, to identify areas of disparities between subgroups of...

  13. Recovery Action Mapping Tool

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Recovery Action Mapping Tool is a web map that allows users to visually interact with and query actions that were developed to recover species listed under the...

  14. Letter of Map Revision

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The National Flood Hazard Layer (NFHL) data incorporates all Digital Flood Insurance Rate Map(DFIRM) databases published by FEMA, and any Letters Of Map Revision...

  15. Branched polynomial covering maps

    DEFF Research Database (Denmark)

    Hansen, Vagn Lundsgaard

    1999-01-01

    A Weierstrass polynomial with multiple roots in certain points leads to a branched covering map. With this as the guiding example, we formally define and study the notion of a branched polynomial covering map. We shall prove that many finite covering maps are polynomial outside a discrete branch...... set. Particular studies are made of branched polynomial covering maps arising from Riemann surfaces and from knots in the 3-sphere....

  16. Map of the Physical Sciences

    Energy Technology Data Exchange (ETDEWEB)

    Boyack, Kevin W.

    1999-07-02

    Various efforts to map the structure of science have been undertaken over the years. Using a new tool, VxInsight{trademark}, we have mapped and displayed 3000 journals in the physical sciences. This map is navigable and interactively reveals the structure of science at many different levels. Science mapping studies are typically focused at either the macro-or micro-level. At a macro-level such studies seek to determine the basic structural units of science and their interrelationships. The majority of studies are performed at the discipline or specialty level, and seek to inform science policy and technical decision makers. Studies at both levels probe the dynamic nature of science, and the implications of the changes. A variety of databases and methods have been used for these studies. Primary among databases are the citation indices (SCI and SSCI) from the Institute for Scientific Information, which have gained widespread acceptance for bibliometric studies. Maps are most often based on computed similarities between journal articles (co-citation), keywords or topics (co-occurrence or co-classification), or journals (journal-journal citation counts). Once the similarity matrix is defined, algorithms are used to cluster the data.

  17. Introduction: Hazard mapping

    Science.gov (United States)

    Baum, Rex L.; Miyagi, Toyohiko; Lee, Saro; Trofymchuk, Oleksandr M

    2014-01-01

    Twenty papers were accepted into the session on landslide hazard mapping for oral presentation. The papers presented susceptibility and hazard analysis based on approaches ranging from field-based assessments to statistically based models to assessments that combined hydromechanical and probabilistic components. Many of the studies have taken advantage of increasing availability of remotely sensed data and nearly all relied on Geographic Information Systems to organize and analyze spatial data. The studies used a range of methods for assessing performance and validating hazard and susceptibility models. A few of the studies presented in this session also included some element of landslide risk assessment. This collection of papers clearly demonstrates that a wide range of approaches can lead to useful assessments of landslide susceptibility and hazard.

  18. Multi-moment maps

    DEFF Research Database (Denmark)

    Swann, Andrew Francis; Madsen, Thomas Bruun

    2012-01-01

    We introduce a notion of moment map adapted to actions of Lie groups that preserve a closed three-form. We show existence of our multi-moment maps in many circumstances, including mild topological assumptions on the underlying manifold. Such maps are also shown to exist for all groups whose second...

  19. Diffusion Based Photon Mapping

    DEFF Research Database (Denmark)

    Schjøth, Lars; Fogh Olsen, Ole; Sporring, Jon

    2007-01-01

    . To address this problem we introduce a novel photon mapping algorithm based on nonlinear anisotropic diffusion. Our algorithm adapts according to the structure of the photon map such that smoothing occurs along edges and structures and not across. In this way we preserve the important illumination features......, while eliminating noise. We call our method diffusion based photon mapping....

  20. Diffusion Based Photon Mapping

    DEFF Research Database (Denmark)

    Schjøth, Lars; Olsen, Ole Fogh; Sporring, Jon

    2006-01-01

    . To address this problem we introduce a novel photon mapping algorithm based on nonlinear anisotropic diffusion. Our algorithm adapts according to the structure of the photon map such that smoothing occurs along edges and structures and not across. In this way we preserve the important illumination features......, while eliminating noise. We call our method diffusion based photon mapping....

  1. On parabolic external maps

    DEFF Research Database (Denmark)

    Lomonaco, Luna; Petersen, Carsten Lunde; Shen, Weixiao

    2017-01-01

    We prove that any C1+BV degree d ≥ 2 circle covering h having all periodic orbits weakly expanding, is conjugate by a C1+BV diffeomorphism to a metrically expanding map. We use this to connect the space of parabolic external maps (coming from the theory of parabolic-like maps) to metrically expan...

  2. A gene-based high-resolution comparative radiation hybrid map as a framework for genome sequence assembly of a bovine chromosome 6 region associated with QTL for growth, body composition, and milk performance traits

    Directory of Open Access Journals (Sweden)

    Laurent Pascal

    2006-03-01

    Full Text Available Abstract Background A number of different quantitative trait loci (QTL for various phenotypic traits, including milk production, functional, and conformation traits in dairy cattle as well as growth and body composition traits in meat cattle, have been mapped consistently in the middle region of bovine chromosome 6 (BTA6. Dense genetic and physical maps and, ultimately, a fully annotated genome sequence as well as their mutual connections are required to efficiently identify genes and gene variants responsible for genetic variation of phenotypic traits. A comprehensive high-resolution gene-rich map linking densely spaced bovine markers and genes to the annotated human genome sequence is required as a framework to facilitate this approach for the region on BTA6 carrying the QTL. Results Therefore, we constructed a high-resolution radiation hybrid (RH map for the QTL containing chromosomal region of BTA6. This new RH map with a total of 234 loci including 115 genes and ESTs displays a substantial increase in loci density compared to existing physical BTA6 maps. Screening the available bovine genome sequence resources, a total of 73 loci could be assigned to sequence contigs, which were already identified as specific for BTA6. For 43 loci, corresponding sequence contigs, which were not yet placed on the bovine genome assembly, were identified. In addition, the improved potential of this high-resolution RH map for BTA6 with respect to comparative mapping was demonstrated. Mapping a large number of genes on BTA6 and cross-referencing them with map locations in corresponding syntenic multi-species chromosome segments (human, mouse, rat, dog, chicken achieved a refined accurate alignment of conserved segments and evolutionary breakpoints across the species included. Conclusion The gene-anchored high-resolution RH map (1 locus/300 kb for the targeted region of BTA6 presented here will provide a valuable platform to guide high-quality assembling and

  3. Concept mapping for learners of all ages

    Directory of Open Access Journals (Sweden)

    Nancy L. Gallenstein

    2013-02-01

    Full Text Available Concept mapping is an inquiry technique that provides students at all ages with opportunities to demonstrate learning through performance. A concept map refers to a graphic/visual representation of concepts with linking connections that show various relationships between concepts (Novak & Gowin, 1984. Assessment is an ongoing process integrated with instruction across subject areas. The National Council of Teachers of Mathematics (NCTM emphasizes that assessment should focus on both the enhancement of student learning as well as serve as a valuable tool for making instructional decisions (NCTM, 2000. Assessment activities can take on a variety of forms, one being performance tasks. In this manuscript, an explanation of concept mapping is provided for learners ages 3 – 12 along with several examples of concept maps for young learners, including examples from an assessment project in the subject area of mathematics. Also presented are the numerous benefits of the concept mapping technique for both students and teachers.

  4. Digitised Maps in the Danish Map Collection

    OpenAIRE

    Annie Lenschau-Teglers; Vivi Gade Rønsberg

    2005-01-01

    As in the rest of the library world, The Royal Library in Copenhagen is in the process of digitising its collections. At the moment we are mainly working on the handwritten manual catalogue - but digitising the material is also a major working assignment. The Map Collection at The Royal Library has today divided the effort in digitising its materials into 3 groups: 1. Digitised maps as a vital addition to the records in our bibliographic database REX 2. Digitised maps presented as a Digital F...

  5. Habitat Mapping Cruise (HB0805, EK60)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Objectives are to: 1) perform multibeam mapping of transitional and deepwater habitats in Hudson Canyon (off New Jersey) with the National Institute of Undersea...

  6. Sonic Fiction as the Mapping of Difference

    DEFF Research Database (Denmark)

    Holmboe, Rasmus; Stricker, Jan Høgh

    2015-01-01

    The here proposed audio paper/audio lecture performance is an iteration of a site-specific participatory performance piece by Danish artist, composer and musician, Andreas Führer. The piece, which has the title THE MAP IS NOT THE TERRITORY D’OR, is a scored sound walk, which shows a map designati......) as a discussion and contextualisation of sonic materialist (Cox, 2011) and signifying representationalist (Kim-Cohen, 2009) positions....

  7. Mapping of wine industry

    OpenAIRE

    Віліна Пересадько; Надія Максименко; Катерина Біла

    2016-01-01

    Having reviewed a variety of approaches to understanding the essence of wine industry, having studied the modern ideas about the future of wine industry, having analyzed more than 50 maps from the Internet we have set the trends and special features of wine industry mapping in the world, such as: - the vast majority of maps displays the development of the industry at regional or national level, whereas there are practically no world maps; - wine-growing regions are represented on maps very un...

  8. Branched polynomial covering maps

    DEFF Research Database (Denmark)

    Hansen, Vagn Lundsgaard

    2002-01-01

    A Weierstrass polynomial with multiple roots in certain points leads to a branched covering map. With this as the guiding example, we formally define and study the notion of a branched polynomial covering map. We shall prove that many finite covering maps are polynomial outside a discrete branch ...... set. Particular studies are made of branched polynomial covering maps arising from Riemann surfaces and from knots in the 3-sphere. (C) 2001 Elsevier Science B.V. All rights reserved.......A Weierstrass polynomial with multiple roots in certain points leads to a branched covering map. With this as the guiding example, we formally define and study the notion of a branched polynomial covering map. We shall prove that many finite covering maps are polynomial outside a discrete branch...

  9. Distributed autonomous mapping of indoor environments

    Science.gov (United States)

    Rogers, J.; Paluri, M.; Cunningham, A.; Christensen, H. I.; Michael, N.; Kumar, V.; Ma, J.; Matthies, L.

    2011-06-01

    This paper describes the results of a Joint Experiment performed on behalf of the MAST CTA. The system developed for the Joint Experiment makes use of three robots which work together to explore and map an unknown environment. Each of the robots used in this experiment is equipped with a laser scanner for measuring walls and a camera for locating doorways. Information from both of these types of structures is concurrently incorporated into each robot's local map using a graph based SLAM technique. A Distributed-Data-Fusion algorithm is used to efficiently combine local maps from each robot into a shared global map. Each robot computes a compressed local feature map and transmits it to neighboring robots, which allows each robot to merge its map with the maps of its neighbors. Each robot caches the compressed maps from its neighbors, allowing it to maintain a coherent map with a common frame of reference. The robots utilize an exploration strategy to efficiently cover the unknown environment which allows collaboration on an unreliable communications channel. As each new branching point is discovered by a robot, it broadcasts the information about where this point is along with the robot's path from a known landmark to the other robots. When the next robot reaches a dead-end, new branching points are allocated by auction. In the event of communication interruption, the robot which observed the branching point will eventually explore it; therefore, the exploration is complete in the face of communication failure.

  10. A framework for evaluating and utilizing medical terminology mappings.

    Science.gov (United States)

    Hussain, Sajjad; Sun, Hong; Sinaci, Anil; Erturkmen, Gokce Banu Laleci; Mead, Charles; Gray, Alasdair J G; McGuinness, Deborah L; Prud'Hommeaux, Eric; Daniel, Christel; Forsberg, Kerstin

    2014-01-01

    Use of medical terminologies and mappings across them are considered to be crucial pre-requisites for achieving interoperable eHealth applications. Built upon the outcomes of several research projects, we introduce a framework for evaluating and utilizing terminology mappings that offers a platform for i) performing various mappings strategies, ii) representing terminology mappings together with their provenance information, and iii) enabling terminology reasoning for inferring both new and erroneous mappings. We present the results of the introduced framework from SALUS project where we evaluated the quality of both existing and inferred terminology mappings among standard terminologies.

  11. Current trends in geomorphological mapping

    Science.gov (United States)

    Seijmonsbergen, A. C.

    2012-04-01

    Geomorphological mapping is a world currently in motion, driven by technological advances and the availability of new high resolution data. As a consequence, classic (paper) geomorphological maps which were the standard for more than 50 years are rapidly being replaced by digital geomorphological information layers. This is witnessed by the following developments: 1. the conversion of classic paper maps into digital information layers, mainly performed in a digital mapping environment such as a Geographical Information System, 2. updating the location precision and the content of the converted maps, by adding more geomorphological details, taken from high resolution elevation data and/or high resolution image data, 3. (semi) automated extraction and classification of geomorphological features from digital elevation models, broadly separated into unsupervised and supervised classification techniques and 4. New digital visualization / cartographic techniques and reading interfaces. Newly digital geomorphological information layers can be based on manual digitization of polygons using DEMs and/or aerial photographs, or prepared through (semi) automated extraction and delineation of geomorphological features. DEMs are often used as basis to derive Land Surface Parameter information which is used as input for (un) supervised classification techniques. Especially when using high-res data, object-based classification is used as an alternative to traditional pixel-based classifications, to cluster grid cells into homogeneous objects, which can be classified as geomorphological features. Classic map content can also be used as training material for the supervised classification of geomorphological features. In the classification process, rule-based protocols, including expert-knowledge input, are used to map specific geomorphological features or entire landscapes. Current (semi) automated classification techniques are increasingly able to extract morphometric, hydrological

  12. Visual SLAM Using Variance Grid Maps

    Science.gov (United States)

    Howard, Andrew B.; Marks, Tim K.

    2011-01-01

    An algorithm denoted Gamma-SLAM performs further processing, in real time, of preprocessed digitized images acquired by a stereoscopic pair of electronic cameras aboard an off-road robotic ground vehicle to build accurate maps of the terrain and determine the location of the vehicle with respect to the maps. Part of the name of the algorithm reflects the fact that the process of building the maps and determining the location with respect to them is denoted simultaneous localization and mapping (SLAM). Most prior real-time SLAM algorithms have been limited in applicability to (1) systems equipped with scanning laser range finders as the primary sensors in (2) indoor environments (or relatively simply structured outdoor environments). The few prior vision-based SLAM algorithms have been feature-based and not suitable for real-time applications and, hence, not suitable for autonomous navigation on irregularly structured terrain. The Gamma-SLAM algorithm incorporates two key innovations: Visual odometry (in contradistinction to wheel odometry) is used to estimate the motion of the vehicle. An elevation variance map (in contradistinction to an occupancy or an elevation map) is used to represent the terrain. The Gamma-SLAM algorithm makes use of a Rao-Blackwellized particle filter (RBPF) from Bayesian estimation theory for maintaining a distribution over poses and maps. The core idea of the RBPF approach is that the SLAM problem can be factored into two parts: (1) finding the distribution over robot trajectories, and (2) finding the map conditioned on any given trajectory. The factorization involves the use of a particle filter in which each particle encodes both a possible trajectory and a map conditioned on that trajectory. The base estimate of the trajectory is derived from visual odometry, and the map conditioned on that trajectory is a Cartesian grid of elevation variances. In comparison with traditional occupancy or elevation grid maps, the grid elevation variance

  13. On palaeogeographic map

    Directory of Open Access Journals (Sweden)

    Zeng-Zhao Feng

    2016-01-01

    Full Text Available The palaeogeographic map is a graphic representation of physical geographical characteristics in geological history periods and human history periods. It is the most important result of palaeogeographic study. The author, as the Editor-in-Chief of Journal of Palaeogeography, Chinese Edition and English Edition, aimed at the problems of the articles submitted to and published in the Journal of Palaeogeography in recent years and the relevant papers and books of others, and integrated with his practice of palaeogeographic study and mapping, wrote this paper. The content mainly includes the data of palaeogeographic mapping, the problems of palaeogeographic mapping method, the “Single factor analysis and multifactor comprehensive mapping method —— Methodology of quantitative lithofacies palaeogeography”, i.e., the “4 steps mapping method”, the nomenclature of each palaeogeographic unit in palaeogeographic map, the explanation of each palaeogeographic unit in palaeogeographic map, the explanation of significance of palaeogeographic map and palaeogeographic article, the evaluative standards of palaeogeographic map and palaeogeographic article, and the self-evaluation. Criticisms and corrections are welcome.

  14. Mapping Urban Social Divisions

    Directory of Open Access Journals (Sweden)

    Susan Ball

    2010-05-01

    Full Text Available Against the background of increased levels of interest in space and images beyond the field of geography, this article (re- introduces earlier work on the semiotics of maps undertaken by geographers in the 1960s. The data limitations, purpose and cultural context in which a user interprets a map's codes and conventions are highlighted in this work, which remains relevant to the interpretation of maps—new and old—forty years later. By means of drawing on geography's contribution to the semiotics of maps, the article goes on to examine the concept of urban social divisions as represented in map images. Using a small number of map images, including two of the most widely known maps of urban social division in Europe and North America, the roles of context, data and purpose in the production and interpretation of maps are discussed. By presenting the examples chronologically the article shows that although advances in data collection and manipulation have allowed researchers to combine different social variables in maps of social division, and to interact with map images, work by geographers on the semiotics of maps is no less relevant today than when it was first proposed forty years ago. URN: urn:nbn:de:0114-fqs1002372

  15. ANNUAL INTERVIEWS (MAPS)

    CERN Multimedia

    2003-01-01

    For the performance appraisal of reference year 2003, the interview calendar has been fixed between 1 January and 31 March 2004. This new calendar gives a better time schedule to the supervisors to conduct the interviews. This may also be necessary due to the roles of different supervisors resulting from the particular situations of the new CERN structure as from 2004. With this later time limit, the new departments are invited to strictly respect the target date of 31 March. The report form template is as last year available on the HR Division Website. A banner on the internal homepage: http://cern.ch/hr-div will lead directly to the page with the form. The personal data for the first page of the form can be generated by each divisional hierarchy, by the Divisional Administrative Officer (DAO) or by the staff member himself via HRT. Following discussions about the first two years of MAPS, and in order to improve the performance appraisal process, some modifications have been brought to section 2 (Assessme...

  16. Implementing Parallel Google Map-Reduce in Eden

    DEFF Research Database (Denmark)

    Berthold, Jost; Dieterle, Mischa; Loogen, Rita

    2009-01-01

    Recent publications have emphasised map-reduce as a general programming model (labelled Google map-reduce), and described existing high-performance implementations for large data sets. We present two parallel implementations for this Google map-reduce skeleton, one following earlier work, and one...... of the Google map-reduce skeleton in usage and performance, and deliver runtime analyses for example applications. Although very flexible, the Google map-reduce skeleton is often too general, and typical examples reveal a better runtime behaviour using alternative skeletons....

  17. Mapping of wine industry

    Directory of Open Access Journals (Sweden)

    Віліна Пересадько

    2016-10-01

    Full Text Available Having reviewed a variety of approaches to understanding the essence of wine industry, having studied the modern ideas about the future of wine industry, having analyzed more than 50 maps from the Internet we have set the trends and special features of wine industry mapping in the world, such as: - the vast majority of maps displays the development of the industry at regional or national level, whereas there are practically no world maps; - wine-growing regions are represented on maps very unevenly; - all existing maps of the industry could be classified as analytical ascertaining inventory type; - the dominant ways of cartographic representation are area method and qualitative background method, sign method and collation maps are rarely used; - basically all the Internet maps have low quality as they are scanned images with poor resolution; - the special feature of maps published lately is lack of geographical basis (except for state borders and coastline. We created wine production and consumption world map «Wine Industry» in the scale of 1:60 000 000 with simple geographical basis (state names, state borders, major rivers, coastline. It was concluded that from the methodological point of view it is incorrect not to show geographical basis on maps of wine industry. Analysis of this map allowed us to identify areas of traditional wine-making, potential wine-making areas and countries which claim to be the world leaders in the field of wine production. We found disbalans between wine production and wine consumption - increasing wine production in South America, China and the United States and increasing wine consumption (mainly due to the import products in countries where the grape is not the primary agricultural product.

  18. The global thermospheric mapping study

    International Nuclear Information System (INIS)

    Oliver, W.L.; Salah, J.E.

    1988-01-01

    The Global Thermospheric Mapping Study (GTMS) is a multitechnique experimental pilot study of the Earth's thermosphere designed to map simultaneously its spatial and temporal morphology. This paper provides the background for the study and presents the analysis techniques employed at Millstone Hill and results to date on thermospheric structure and dynamics. The first latitudinal-temporal maps of exospheric temperature obtained from the incoherent scatter radar chain at 70W meridian are presented for the two solstice periods, revealing substantial seasonal differences between them. The observed structure shows a relatively depressed temperature at high latitude in summer in contrast to the mass spectrometer/incoherent scatter 1983 [MSIS-83] empirical model, which shows a maximum temperature at polar latitudes. The MSIS-83 model predictions are in good agreement with the observed latitudinal-temporal structure in winter. Comparison with the numerical predictions made for the June 26-28, 1984 period with the National Center for Atmospheric Research thermospheric general circulation model shows reasonable agreement in the latitudinal gradient but the observations indicate a cooler thermosphere by several hundred degrees. Neutral winds at mid-latitudes are presented showing the expected strong southward winds at night, which are found to be consistent with the temperature gradients observed in the latitudinal maps. There is good agreement in the June winds between the available numerical model calculations and the observations. Work performed elsewhere on the GTMS data base is summarized for completeness

  19. Deep Mapping and Spatial Anthropology

    Directory of Open Access Journals (Sweden)

    Les Roberts

    2016-01-01

    Full Text Available This paper provides an introduction to the Humanities Special Issue on “Deep Mapping”. It sets out the rationale for the collection and explores the broad-ranging nature of perspectives and practices that fall within the “undisciplined” interdisciplinary domain of spatial humanities. Sketching a cross-current of ideas that have begun to coalesce around the concept of “deep mapping”, the paper argues that rather than attempting to outline a set of defining characteristics and “deep” cartographic features, a more instructive approach is to pay closer attention to the multivalent ways deep mapping is performatively put to work. Casting a critical and reflexive gaze over the developing discourse of deep mapping, it is argued that what deep mapping “is” cannot be reduced to the otherwise a-spatial and a-temporal fixity of the “deep map”. In this respect, as an undisciplined survey of this increasing expansive field of study and practice, the paper explores the ways in which deep mapping can engage broader discussion around questions of spatial anthropology.

  20. Minimalism through intraoperative functional mapping.

    Science.gov (United States)

    Berger, M S

    1996-01-01

    Intraoperative stimulation mapping may be used to avoid unnecessary risk to functional regions subserving language and sensori-motor pathways. Based on the data presented here, language localization is variable in the entire population, with only certainty existing for the inferior frontal region responsible for motor speech. Anatomical landmarks such as the anterior temporal tip for temporal lobe language sites and the posterior aspect of the lateral sphenoid wing for the frontal lobe language zones are unreliable in avoiding postoperative aphasias. Thus, individual mapping to identify essential language sites has the greatest likelihood of avoiding permanent deficits in naming, reading, and motor speech. In a similar approach, motor and sensory pathways from the cortex and underlying white matter may be reliably stimulated and mapped in both awake and asleep patients. Although these techniques require an additional operative time and equipment nominally priced, the result is often gratifying, as postoperative morbidity has been greatly reduced in the process of incorporating these surgical strategies. The patients quality of life is improved in terms of seizure control, with or without antiepileptic drugs. This avoids having to perform a second costly operative procedure, which is routinely done when extraoperative stimulation and recording is done via subdural grids. In addition, an aggressive tumor resection at the initial operation lengthens the time to tumor recurrence and often obviates the need for a subsequent reoperation. Thus, intraoperative functional mapping may be best alluded to as a surgical technique that results in "minimalism in the long term".

  1. Genetic maps and physical units

    International Nuclear Information System (INIS)

    Karunakaran, V.; Holt, G.

    1976-01-01

    The relationships between physical and genetic units are examined. Genetic mapping involves the detection of linkage of genes and the measurement of recombination frequencies. The genetic distance is measured in map units and is proportional to the recombination frequencies between linked markers. Physical mapping of genophores, particularly the simple genomes of bacteriophages and bacterial plasmids can be achieved through heteroduplex analysis. Genetic distances are dependent on recombination frequencies and, therefore, can only be correlated accurately with physical unit lengths if the recombination frequency is constant throughout the entire genome. Methods are available to calculate the equivalent length of DNA per average map unit in different organisms. Such estimates indicate significant differences from one organism to another. Gene lengths can also be calculated from the number of amino acids in a specified polypeptide and relating this to the number of nucleotides required to code for such a polypeptide. Many attempts have been made to relate microdosimetric measurements to radiobiological data. For irradiation effects involving deletion of genetic material such a detailed correlation may be possible in systems where heteroduplex analysis or amino acid sequencing can be performed. The problems of DNA packaging and other functional associations within the cell in interpreting data is discussed

  2. Introduction to "Mapping Vietnameseness"

    OpenAIRE

    Hue-Tam Ho Tai

    2016-01-01

    Vietnam and China are currently engaged in a map war, with each country using ancient maps to buttress its claims to territorial sovereignty over some uninhabited islands in the South China Sea (in Chinese terminology), also known as the Eastern Sea (in Vietnamese). But what do maps in fact represent? What is meant by “territory”? How are territorial limits conceived? These questions were raised in a May 2015 workshop inspired by Thongchai Winichakul’s Siam Mapped: A History of the Geo-Body o...

  3. North America pipeline map

    International Nuclear Information System (INIS)

    Anon.

    2005-01-01

    This map presents details of pipelines currently in place throughout North America. Fifty-nine natural gas pipelines are presented, as well as 16 oil pipelines. The map also identifies six proposed natural gas pipelines. Major cities, roads and highways are included as well as state and provincial boundaries. The National Petroleum Reserve is identified, as well as the Arctic National Wildlife Refuge. The following companies placed advertisements on the map with details of the services they provide relating to pipeline management and construction: Ferus Gas Industries Trust; Proline; SulfaTreat Direct Oxidation; and TransGas. 1 map

  4. Open land use map

    OpenAIRE

    Mildorf, T.; Charvát, K.; Jezek, J.; Templer, Simon; Malewski, Christian

    2014-01-01

    Open Land Use Map is an initiative that has been started by the Plan4business project and that will be extended as part of the SDI4Apps project in the future. This service aims to create an improved worldwide land use map. The initial map will be prepared using the CORINE Land Cover, Global Cover dataset and Open Street Map. Contributors, mainly volunteers, will able to change the geometry and assign up-to-date land use according to the HILUCS specification. For certain regions more detailed ...

  5. Canonical, stable, general mapping using context schemes.

    Science.gov (United States)

    Novak, Adam M; Rosen, Yohei; Haussler, David; Paten, Benedict

    2015-11-15

    Sequence mapping is the cornerstone of modern genomics. However, most existing sequence mapping algorithms are insufficiently general. We introduce context schemes: a method that allows the unambiguous recognition of a reference base in a query sequence by testing the query for substrings from an algorithmically defined set. Context schemes only map when there is a unique best mapping, and define this criterion uniformly for all reference bases. Mappings under context schemes can also be made stable, so that extension of the query string (e.g. by increasing read length) will not alter the mapping of previously mapped positions. Context schemes are general in several senses. They natively support the detection of arbitrary complex, novel rearrangements relative to the reference. They can scale over orders of magnitude in query sequence length. Finally, they are trivially extensible to more complex reference structures, such as graphs, that incorporate additional variation. We demonstrate empirically the existence of high-performance context schemes, and present efficient context scheme mapping algorithms. The software test framework created for this study is available from https://registry.hub.docker.com/u/adamnovak/sequence-graphs/. anovak@soe.ucsc.edu Supplementary data are available at Bioinformatics online. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  6. Contig Maps and Genomic Sequencing Identify Candidate Genes in the Usher 1C Locus

    Science.gov (United States)

    Higgins, Michael J.; Day, Colleen D.; Smilinich, Nancy J.; Ni, L.; Cooper, Paul R.; Nowak, Norma J.; Davies, Chris; de Jong, Pieter J.; Hejtmancik, Fielding; Evans, Glen A.; Smith, Richard J.H.; Shows, Thomas B.

    1998-01-01

    Usher syndrome 1C (USH1C) is a congenital condition manifesting profound hearing loss, the absence of vestibular function, and eventual retinal degeneration. The USH1C locus has been mapped genetically to a 2- to 3-cM interval in 11p14–15.1 between D11S899 and D11S861. In an effort to identify the USH1C disease gene we have isolated the region between these markers in yeast artificial chromosomes (YACs) using a combination of STS content mapping and Alu–PCR hybridization. The YAC contig is ∼3.5 Mb and has located several other loci within this interval, resulting in the order CEN-LDHA-SAA1-TPH-D11S1310-(D11S1888/KCNC1)-MYOD1-D11S902D11S921-D11S1890-TEL. Subsequent haplotyping and homozygosity analysis refined the location of the disease gene to a 400-kb interval between D11S902 and D11S1890 with all affected individuals being homozygous for the internal marker D11S921. To facilitate gene identification, the critical region has been converted into P1 artificial chromosome (PAC) clones using sequence-tagged sites (STSs) mapped to the YAC contig, Alu–PCR products generated from the YACs, and PAC end probes. A contig of >50 PAC clones has been assembled between D11S1310 and D11S1890, confirming the order of markers used in haplotyping. Three PAC clones representing nearly two-thirds of the USH1C critical region have been sequenced. PowerBLAST analysis identified six clusters of expressed sequence tags (ESTs), two known genes (BIR,SUR1) mapped previously to this region, and a previously characterized but unmapped gene NEFA (DNA binding/EF hand/acidic amino-acid-rich). GRAIL analysis identified 11 CpG islands and 73 exons of excellent quality. These data allowed the construction of a transcription map for the USH1C critical region, consisting of three known genes and six or more novel transcripts. Based on their map location, these loci represent candidate disease loci for USH1C. The NEFA gene was assessed as the USH1C locus by the sequencing of an amplified NEFA

  7. Mapping monthly rainfall erosivity in Europe

    DEFF Research Database (Denmark)

    Ballabio, C; Meusburger, K; Klik, A

    2017-01-01

    to Eastern Europe. The maps also show a clear delineation of areas with different erosivity seasonal patterns, whose spatial outline was evidenced by cluster analysis. The monthly erosivity maps can be used to develop composite indicators that map both intra-annual variability and concentration of erosive...... and seasonal R-factor maps and assess rainfall erosivity both spatially and temporally. During winter months, significant rainfall erosivity is present only in part of the Mediterranean countries. A sudden increase of erosivity occurs in major part of European Union (except Mediterranean basin, western part...... selected among various statistical models to perform the spatial interpolation due to its excellent performance, ability to model non-linearity and interpretability. The monthly prediction is an order more difficult than the annual one as it is limited by the number of covariates and, for consistency...

  8. On circle map coupled map lattice

    CERN Document Server

    Ahmed, E

    2002-01-01

    Circle map in one and two dimensions is studied. Both its stability, synchronization using bounded control and persistence is discussed. This work is expected to be applicable in ecology where spatial effects are known to be important. Also it will be relevant to systems where delay effects are not negligible.

  9. EX1103L1: Exploration and Mapping, Galapagos Spreading Center: Mapping, CTD and Tow-yo

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This project will be a transit from San Diego, CA to the Galapagos Spreading Center, where multibeam mapping, CTD casts, and CTD tow-yo operations will be performed....

  10. Mapping online consumer search

    NARCIS (Netherlands)

    Bronnenberg, B.J.; Kim, J.; Albuquerque, P.

    2011-01-01

    The authors propose a new method to visualize browsing behavior in so-called product search maps. Manufacturers can use these maps to understand how consumers search for competing products before choice, including how information acquisition and product search are organized along brands, product

  11. Map of Nasca Geoglyphs

    Science.gov (United States)

    Hanzalová, K.; Pavelka, K.

    2013-07-01

    The Czech Technical University in Prague in the cooperation with the University of Applied Sciences in Dresden (Germany) work on the Nasca Project. The cooperation started in 2004 and much work has been done since then. All work is connected with Nasca lines in southern Peru. The Nasca project started in 1995 and its main target is documentation and conservation of the Nasca lines. Most of the project results are presented as WebGIS application via Internet. In the face of the impending destruction of the soil drawings, it is possible to preserve this world cultural heritage for the posterity at least in a digital form. Creating of Nasca lines map is very useful. The map is in a digital form and it is also available as a paper map. The map contains planimetric component of the map, map lettering and altimetry. Thematic folder in this map is a vector layer of the geoglyphs in Nasca/Peru. Basis for planimetry are georeferenced satellite images, altimetry is created from digital elevation model. This map was created in ArcGis software.

  12. Mapping of Outdoor Classrooms.

    Science.gov (United States)

    Horvath, Victor G.

    Mapping symbols adopted by the Michigan Department of Natural Resources are presented with their explanations. In an effort to provide standardization and familiarity teachers and other school people involved in an outdoor education program are encouraged to utilize the same symbols in constructing maps. (DK)

  13. MAP OF NASCA GEOGLYPHS

    Directory of Open Access Journals (Sweden)

    K. Hanzalová

    2013-07-01

    Full Text Available The Czech Technical University in Prague in the cooperation with the University of Applied Sciences in Dresden (Germany work on the Nasca Project. The cooperation started in 2004 and much work has been done since then. All work is connected with Nasca lines in southern Peru. The Nasca project started in 1995 and its main target is documentation and conservation of the Nasca lines. Most of the project results are presented as WebGIS application via Internet. In the face of the impending destruction of the soil drawings, it is possible to preserve this world cultural heritage for the posterity at least in a digital form. Creating of Nasca lines map is very useful. The map is in a digital form and it is also available as a paper map. The map contains planimetric component of the map, map lettering and altimetry. Thematic folder in this map is a vector layer of the geoglyphs in Nasca/Peru. Basis for planimetry are georeferenced satellite images, altimetry is created from digital elevation model. This map was created in ArcGis software.

  14. Diffusion Based Photon Mapping

    DEFF Research Database (Denmark)

    Schjøth, Lars; Sporring, Jon; Fogh Olsen, Ole

    2008-01-01

    . To address this problem, we introduce a photon mapping algorithm based on nonlinear anisotropic diffusion. Our algorithm adapts according to the structure of the photon map such that smoothing occurs along edges and structures and not across. In this way, we preserve important illumination features, while...

  15. Maps between Grassmann manifolds

    Indian Academy of Sciences (India)

    Parameswaran Sankaran Institute of Mathematical Sciences Chennai, India sankaran@imsc.res.in Indian Academy of Sciences Platinum Jubilee Meeting Hyderabad

    2009-07-02

    Jul 2, 2009 ... Classification of all manifolds (or maps between them) is an impossible task. The coarser, homotopical classification, is relatively easier–but only relatively! Homotopy is, roughly speaking, the study of properties of spaces and maps invariant under continuous deformations. Denote by [X, Y ] the set of all ...

  16. Constructing Maps Collaboratively.

    Science.gov (United States)

    Leinhardt, Gaea; Stainton, Catherine; Bausmith, Jennifer Merriman

    1998-01-01

    Summarizes a study that maintains that students who work together in small groups had a better understanding of map concepts. Discusses why making maps in groups can enhance students' conceptual geographic understanding and offers suggestions for improving geography instructions using small group configurations. Includes statistical and graphic…

  17. Algorithms for necklace maps

    NARCIS (Netherlands)

    Speckmann, B.; Verbeek, K.A.B.

    2015-01-01

    Necklace maps visualize quantitative data associated with regions by placing scaled symbols, usually disks, without overlap on a closed curve (the necklace) surrounding the map regions. Each region is projected onto an interval on the necklace that contains its symbol. In this paper we address the

  18. Text 2 Mind Map

    OpenAIRE

    Iona, John

    2017-01-01

    This is a review of the web resource 'Text 2 Mind Map' www.Text2MindMap.com. It covers what the resource is, and how it might be used in Library and education context, in particular for School Librarians.

  19. Formal genetic maps

    African Journals Online (AJOL)

    Mohammad Saad Zaghloul Salem

    2014-12-24

    Dec 24, 2014 ... ome/transcriptome/proteome, experimental induced maps that are intentionally designed and con- ... genetic maps imposed their application in nearly all fields of medical genetics including ..... or genes located adjacent to, or near, them. ...... types of markers, e.g., clinical markers (eye color), genomic.

  20. Bodily maps of emotions.

    Science.gov (United States)

    Nummenmaa, Lauri; Glerean, Enrico; Hari, Riitta; Hietanen, Jari K

    2014-01-14

    Emotions are often felt in the body, and somatosensory feedback has been proposed to trigger conscious emotional experiences. Here we reveal maps of bodily sensations associated with different emotions using a unique topographical self-report method. In five experiments, participants (n = 701) were shown two silhouettes of bodies alongside emotional words, stories, movies, or facial expressions. They were asked to color the bodily regions whose activity they felt increasing or decreasing while viewing each stimulus. Different emotions were consistently associated with statistically separable bodily sensation maps across experiments. These maps were concordant across West European and East Asian samples. Statistical classifiers distinguished emotion-specific activation maps accurately, confirming independence of topographies across emotions. We propose that emotions are represented in the somatosensory system as culturally universal categorical somatotopic maps. Perception of these emotion-triggered bodily changes may play a key role in generating consciously felt emotions.

  1. Application of ecological mapping

    International Nuclear Information System (INIS)

    Sherk, J.A.

    1982-01-01

    The US Fish and Wildlife Service has initiated the production of a comprehensive ecological inventory map series for use as a major new planning tool. Important species data along with special land use designations are displayed on 1:250,000 scale topographic base maps. Sets of maps have been published for the Atlantic and Pacific coastal areas of the United States. Preparation of a map set for the Gulf of Mexico is underway at the present time. Potential application of ecological inventory map series information to a typical land disposal facility could occur during the narrowing of the number of possible disposal sites, the design of potential disposal site studies of ecological resources, the preparation of the environmental report, and the regulatory review of license applications. 3 figures, 3 tables

  2. The projective heat map

    CERN Document Server

    Schwartz, Richard Evan

    2017-01-01

    This book introduces a simple dynamical model for a planar heat map that is invariant under projective transformations. The map is defined by iterating a polygon map, where one starts with a finite planar N-gon and produces a new N-gon by a prescribed geometric construction. One of the appeals of the topic of this book is the simplicity of the construction that yet leads to deep and far reaching mathematics. To construct the projective heat map, the author modifies the classical affine invariant midpoint map, which takes a polygon to a new polygon whose vertices are the midpoints of the original. The author provides useful background which makes this book accessible to a beginning graduate student or advanced undergraduate as well as researchers approaching this subject from other fields of specialty. The book includes many illustrations, and there is also a companion computer program.

  3. Smart "geomorphological" map browsing - a tale about geomorphological maps and the internet

    Science.gov (United States)

    Geilhausen, M.; Otto, J.-C.

    2012-04-01

    With the digital production of geomorphological maps, the dissemination of research outputs now extends beyond simple paper products. Internet technologies can contribute to both, the dissemination of geomorphological maps and access to geomorphologic data and help to make geomorphological knowledge available to a greater public. Indeed, many national geological surveys employ end-to-end digital workflows from data capture in the field to final map production and dissemination. This paper deals with the potential of web mapping applications and interactive, portable georeferenced PDF maps for the distribution of geomorphological information. Web mapping applications such as Google Maps have become very popular and widespread and increased the interest and access to mapping. They link the Internet with GIS technology and are a common way of presenting dynamic maps online. The GIS processing is performed online and maps are visualised in interactive web viewers characterised by different capabilities such as zooming, panning or adding further thematic layers, with the map refreshed after each task. Depending on the system architecture and the components used, advanced symbology, map overlays from different applications and sources and their integration into a Desktop GIS are possible. This interoperability is achieved through the use of international open standards that include mechanisms for the integration and visualisation of information from multiple sources. The portable document format (PDF) is commonly used for printing and is a standard format that can be processed by many graphic software and printers without loss of information. A GeoPDF enables the sharing of geospatial maps and data in PDF documents. Multiple, independent map frames with individual spatial reference systems are possible within a GeoPDF, for example, for map overlays or insets. Geospatial functionality of a GeoPDF includes scalable map display, layer visibility control, access to attribute

  4. Unexpected Relationships and Inbreeding in HapMap Phase III Populations

    Science.gov (United States)

    Stevens, Eric L.; Baugher, Joseph D.; Shirley, Matthew D.; Frelin, Laurence P.; Pevsner, Jonathan

    2012-01-01

    Correct annotation of the genetic relationships between samples is essential for population genomic studies, which could be biased by errors or omissions. To this end, we used identity-by-state (IBS) and identity-by-descent (IBD) methods to assess genetic relatedness of individuals within HapMap phase III data. We analyzed data from 1,397 individuals across 11 ethnic populations. Our results support previous studies (Pemberton et al., 2010; Kyriazopoulou-Panagiotopoulou et al., 2011) assessing unknown relatedness present within this population. Additionally, we present evidence for 1,657 novel pairwise relationships across 9 populations. Surprisingly, significant Cotterman's coefficients of relatedness K1 (IBD1) values were detected between pairs of known parents. Furthermore, significant K2 (IBD2) values were detected in 32 previously annotated parent-child relationships. Consistent with a hypothesis of inbreeding, regions of homozygosity (ROH) were identified in the offspring of related parents, of which a subset overlapped those reported in previous studies (Gibson et al. 2010; Johnson et al. 2011). In total, we inferred 28 inbred individuals with ROH that overlapped areas of relatedness between the parents and/or IBD2 sharing at a different genomic locus between a child and a parent. Finally, 8 previously annotated parent-child relationships had unexpected K0 (IBD0) values (resulting from a chromosomal abnormality or genotype error), and 10 previously annotated second-degree relationships along with 38 other novel pairwise relationships had unexpected IBD2 (indicating two separate paths of recent ancestry). These newly described types of relatedness may impact the outcome of previous studies and should inform the design of future studies relying on the HapMap Phase III resource. PMID:23185369

  5. A landslide susceptibility map of Africa

    Science.gov (United States)

    Broeckx, Jente; Vanmaercke, Matthias; Duchateau, Rica; Poesen, Jean

    2017-04-01

    Studies on landslide risks and fatalities indicate that landslides are a global threat to humans, infrastructure and the environment, certainly in Africa. Nonetheless our understanding of the spatial patterns of landslides and rockfalls on this continent is very limited. Also in global landslide susceptibility maps, Africa is mostly underrepresented in the inventories used to construct these maps. As a result, predicted landslide susceptibilities remain subject to very large uncertainties. This research aims to produce a first continent-wide landslide susceptibility map for Africa, calibrated with a well-distributed landslide dataset. As a first step, we compiled all available landslide inventories for Africa. This data was supplemented by additional landslide mapping with Google Earth in underrepresented regions. This way, we compiled 60 landslide inventories from the literature (ca. 11000 landslides) and an additional 6500 landslides through mapping in Google Earth (including 1500 rockfalls). Various environmental variables such as slope, lithology, soil characteristics, land use, precipitation and seismic activity, were investigated for their significance in explaining the observed spatial patterns of landslides. To account for potential mapping biases in our dataset, we used Monte Carlo simulations that selected different subsets of mapped landslides, tested the significance of the considered environmental variables and evaluated the performance of the fitted multiple logistic regression model against another subset of mapped landslides. Based on these analyses, we constructed two landslide susceptibility maps for Africa: one for all landslide types and one excluding rockfalls. In both maps, topography, lithology and seismic activity were the most significant variables. The latter factor may be surprising, given the overall limited degree of seismicity in Africa. However, its significance indicates that frequent seismic events may serve as in important

  6. USGS Topo Base Map from The National Map

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The USGS Topographic Base Map from The National Map. This tile cached web map service combines the most current data services (Boundaries, Names, Transportation,...

  7. Analyzing thematic maps and mapping for accuracy

    Science.gov (United States)

    Rosenfield, G.H.

    1982-01-01

    Two problems which exist while attempting to test the accuracy of thematic maps and mapping are: (1) evaluating the accuracy of thematic content, and (2) evaluating the effects of the variables on thematic mapping. Statistical analysis techniques are applicable to both these problems and include techniques for sampling the data and determining their accuracy. In addition, techniques for hypothesis testing, or inferential statistics, are used when comparing the effects of variables. A comprehensive and valid accuracy test of a classification project, such as thematic mapping from remotely sensed data, includes the following components of statistical analysis: (1) sample design, including the sample distribution, sample size, size of the sample unit, and sampling procedure; and (2) accuracy estimation, including estimation of the variance and confidence limits. Careful consideration must be given to the minimum sample size necessary to validate the accuracy of a given. classification category. The results of an accuracy test are presented in a contingency table sometimes called a classification error matrix. Usually the rows represent the interpretation, and the columns represent the verification. The diagonal elements represent the correct classifications. The remaining elements of the rows represent errors by commission, and the remaining elements of the columns represent the errors of omission. For tests of hypothesis that compare variables, the general practice has been to use only the diagonal elements from several related classification error matrices. These data are arranged in the form of another contingency table. The columns of the table represent the different variables being compared, such as different scales of mapping. The rows represent the blocking characteristics, such as the various categories of classification. The values in the cells of the tables might be the counts of correct classification or the binomial proportions of these counts divided by

  8. US Topo: topographic maps for the nation

    Science.gov (United States)

    Carswell, William J.

    2013-01-01

    US Topo is the next generation of topographic maps from the U.S. Geological Survey (USGS). Arranged in the familiar 7.5-minute quadrangle format, digital US Topo maps are designed to look and feel (and perform) like the traditional paper topographic maps for which the USGS is so well known. In contrast to paper-based maps, US Topo maps provide modern technical advantages that support faster, wider public distribution and enable basic, on-screen geographic analysis for all users. The US Topo quadrangle map has been redesigned so that map elements are visually distinguishable with the imagery turned on and off, while keeping the file size as small as possible. The US Topo map redesign includes improvements to various display factors, including symbol definitions (color, line thickness, line symbology, area fills), layer order, and annotation fonts. New features for 2013 include the following: a raster shaded relief layer, military boundaries, cemeteries and post offices, and a US Topo cartographic symbols legend as an attachment. US Topo quadrangle maps are available free on the Web. Each map quadrangle is constructed in GeoPDF® format using key layers of geographic data (orthoimagery, roads, geographic names, topographic contours, and hydrographic features) from The National Map databases. US Topo quadrangle maps can be printed from personal computers or plotters as complete, full-sized, maps or in customized sections, in a user-desired specific format. Paper copies of the maps can also be purchased from the USGS Store. Download links and a users guide are featured on the US Topo Web site. US Topo users can turn geographic data layers on and off as needed; they can zoom in and out to highlight specific features or see a broader area. File size for each digital 7.5-minute quadrangle, about 30 megabytes. Associated electronic tools for geographic analysis are available free for download. The US Topo provides the Nation with a topographic product that users can

  9. Color on emergency mapping

    Science.gov (United States)

    Jiang, Lili; Qi, Qingwen; Zhang, An

    2007-06-01

    There are so many emergency issues in our daily life. Such as typhoons, tsunamis, earthquake, fires, floods, epidemics, etc. These emergencies made people lose their lives and their belongings. Every day, every hour, even every minute people probably face the emergency, so how to handle it and how to decrease its hurt are the matters people care most. If we can map it exactly before or after the emergencies; it will be helpful to the emergency researchers and people who live in the emergency place. So , through the emergency map, before emergency is occurring we can predict the situation, such as when and where the emergency will be happen; where people can refuge, etc. After disaster, we can also easily assess the lost, discuss the cause and make the lost less. The primary effect of mapping is offering information to the people who care about the emergency and the researcher who want to study it. Mapping allows the viewers to get a spatial sense of hazard. It can also provide the clues to study the relationship of the phenomenon in emergency. Color, as the basic element of the map, it can simplify and clarify the phenomenon. Color can also affects the general perceptibility of the map, and elicits subjective reactions to the map. It is to say, structure, readability, and the reader's psychological reactions can be affected by the use of color.

  10. Cognitive maps and attention.

    Science.gov (United States)

    Hardt, Oliver; Nadel, Lynn

    2009-01-01

    Cognitive map theory suggested that exploring an environment and attending to a stimulus should lead to its integration into an allocentric environmental representation. We here report that directed attention in the form of exploration serves to gather information needed to determine an optimal spatial strategy, given task demands and characteristics of the environment. Attended environmental features may integrate into spatial representations if they meet the requirements of the optimal spatial strategy: when learning involves a cognitive mapping strategy, cues with high codability (e.g., concrete objects) will be incorporated into a map, but cues with low codability (e.g., abstract paintings) will not. However, instructions encouraging map learning can lead to the incorporation of cues with low codability. On the other hand, if spatial learning is not map-based, abstract cues can and will be used to encode locations. Since exploration appears to determine what strategy to apply and whether or not to encode a cue, recognition memory for environmental features is independent of whether or not a cue is part of a spatial representation. In fact, when abstract cues were used in a way that was not map-based, or when they were not used for spatial navigation at all, they were nevertheless recognized as familiar. Thus, the relation between exploratory activity on the one hand and spatial strategy and memory on the other appears more complex than initially suggested by cognitive map theory.

  11. Map updates in a dynamic Voronoi data structure

    DEFF Research Database (Denmark)

    Mioc, Darka; Antón Castro, Francesc/François; Gold, C. M.

    2006-01-01

    In this paper we are using local and sequential map updates in the Voronoi data structure, which allows us to automatically record each event and performed map updates within the system. These map updates are executed through map construction commands that are composed of atomic actions (geometric...... algorithms for addition, deletion, and motion of spatial objects) on the dynamic Voronoi data structure. The formalization of map commands led to the development of a spatial language comprising a set of atomic operations or constructs on spatial primitives (points and lines), powerful enough to define...

  12. Identification of a 2 Mb human ortholog of Drosophila eyes shut/spacemaker that is mutated in patients with retinitis pigmentosa.

    NARCIS (Netherlands)

    Collin, R.W.J.; Littink, K.W.; Klevering, B.J.; Born, L.I. van den; Koenekoop, R.K.; Zonneveld-Vrieling, M.N.; Blokland, E.A.W.; Strom, T.M.; Hoyng, C.B.; Hollander, A.I. den; Cremers, F.P.M.

    2008-01-01

    In patients with autosomal-recessive retinitis pigmentosa (arRP), homozygosity mapping was performed for detection of regions harboring genes that might be causative for RP. In one affected sib pair, a shared homozygous region of 5.0 Mb was identified on chromosome 6, within the RP25 locus. One of

  13. Crowdsourcing The National Map

    Science.gov (United States)

    McCartney, Elizabeth; Craun, Kari J.; Korris, Erin M.; Brostuen, David A.; Moore, Laurence R.

    2015-01-01

    Using crowdsourcing techniques, the US Geological Survey’s (USGS) Volunteered Geographic Information (VGI) project known as “The National Map Corps (TNMCorps)” encourages citizen scientists to collect and edit data about man-made structures in an effort to provide accurate and authoritative map data for the USGS National Geospatial Program’s web-based The National Map. VGI is not new to the USGS, but past efforts have been hampered by available technologies. Building on lessons learned, TNMCorps volunteers are successfully editing 10 different structure types in all 50 states as well as Puerto Rico and the US Virgin Islands.

  14. Region & Gateway Mapping

    OpenAIRE

    Schröter, Derik

    2007-01-01

    State-of-the-art robot mapping approaches are capable of acquiring impressively accurate 2D and 3D models of their environments. To the best of our knowledge, few of them represent structure or acquire models of task-relevant objects. In this work, a new approach to mapping of indoor environments is presented, in which the environment structure in terms of regions and gateways is automatically extracted, while the robot explores. Objects, both in 2D and 3D, are modeled explicitly in those map...

  15. MUTYH Associated Polyposis (MAP)

    DEFF Research Database (Denmark)

    Poulsen, Marie Louise Mølgaard; Bisgaard, M L

    2008-01-01

    Adenomatous Polyposis (FAP) and to a lesser extend Lynch Syndrome, which are caused by germline mutations in the APC and Mismatch Repair (MMR) genes, respectively.Here we review research findings regarding MUTYH interactions, genotypic and phenotypic characteristics of MAP, as well as surveillance......MUTYH Associated Polyposis (MAP), a Polyposis predisposition caused by biallelic mutations in the Base Excision Repair (BER) gene MUTYH, confers a marked risk of colorectal cancer (CRC). The MAP phenotype is difficult to distinguish from other hereditary CRC syndromes. Especially from Familial...

  16. Elevation data for floodplain mapping

    National Research Council Canada - National Science Library

    Committee on Floodplain Mapping Technologies; National Research Council; Division on Earth and Life Studies; National Research Council

    2007-01-01

    .... Elevation Data for Floodplain Mapping shows that there is sufficient two-dimensional base map imagery to meet FEMA's flood map modernization goals, but that the three-dimensional base elevation data...

  17. Northern Hemisphere Synoptic Weather Maps

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Daily Series of Synoptic Weather Maps. Part I consists of plotted and analyzed daily maps of sea-level and 500-mb maps for 0300, 0400, 1200, 1230, 1300, and 1500...

  18. DOT Official County Highway Map

    Data.gov (United States)

    Minnesota Department of Natural Resources — The County Highway Map theme is a scanned and rectified version of the original MnDOT County Highway Map Series. The cultural features on some of these maps may be...

  19. Tools for mapping ecosystem services

    Science.gov (United States)

    Palomo, Ignacio; Adamescu, Mihai; Bagstad, Kenneth J.; Cazacu, Constantin; Klug, Hermann; Nedkov, Stoyan; Burkhard, Benjamin; Maes, Joachim

    2017-01-01

    Mapping tools have evolved impressively in recent decades. From early computerised mapping techniques to current cloud-based mapping approaches, we have witnessed a technological evolution that has facilitated the democratisation of Geographic Information

  20. USACE National Coastal Mapping Program Update

    Science.gov (United States)

    Sylvester, C.

    2017-12-01

    The Joint Airborne Lidar Bathymetry Technical Center of Expertise (JALBTCX) formed in 1998 to support the coastal mapping and charting requirements of the USACE, NAVO, NOAA and USGS. This partnership fielded three generations of airborne lidar bathymeters, executed operational data collection programs within the U.S. and overseas, and advanced research and development in airborne lidar bathymetry and complementary technologies. JALBTCX executes a USACE Headquarters-funded National Coastal Mapping Program (NCMP). Initiated in 2004, the NCMP provides high-resolution, high-accuracy elevation and imagery data along the sandy shorelines of the U.S. on a recurring basis. NCMP mapping activities are coordinated with Federal mapping partners through the Interagency Working Group on Ocean and Coastal Mapping and the 3D Elevation Program. The NCMP, currently in it's third cycle, is performing operations along the East Coast in 2017, after having completed surveys along the Gulf Coast in 2016 and conducting emergency response operations in support of Hurricane Matthew. This presentation will provide an overview of JALBTCX, its history in furthering airborne lidar bathymetry technology to meet emerging mapping requirements, current NCMP operations and data products, and Federal mapping coordination activities.

  1. Programming with Hierarchical Maps

    DEFF Research Database (Denmark)

    Ørbæk, Peter

    This report desribes the hierarchical maps used as a central data structure in the Corundum framework. We describe its most prominent features, ague for its usefulness and briefly describe some of the software prototypes implemented using the technology....

  2. Haz-Map

    Data.gov (United States)

    U.S. Department of Health & Human Services — Haz-Map is an occupational health database designed for health and safety professionals and for consumers seeking information about the adverse effects of workplace...

  3. TOXMAP®: Environmental Health Maps

    Data.gov (United States)

    U.S. Department of Health & Human Services — TOXMAP® is a Geographic Information System (GIS) that uses maps of the United States and Canada to help users visually explore data primarily from the EPA's Toxics...

  4. The CPD Maps System

    Data.gov (United States)

    Department of Housing and Urban Development — CPD Maps includes data on the locations of existing CDBG, HOME, public housing and other HUD-funded community assets, so that users can view past investments...

  5. MetaMap

    Data.gov (United States)

    U.S. Department of Health & Human Services — MetaMap is a highly configurable application developed by the Lister Hill National Center for Biomedical Communications at the National Library of Medicine (NLM) to...

  6. FLOODPLAIN MAPPING, Bandera, TEXAS

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Floodplain Mapping/Redelineation study deliverables depict and quantify the flood risks for the study area. The primary risk classifications used are the...

  7. FLOODPLAIN MAPPING, Atascosa, TEXAS

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Floodplain Mapping/Redelineation study deliverables depict and quantify the flood risks for the study area. The primary risk classifications used are the...

  8. Public Waters Inventory Maps

    Data.gov (United States)

    Minnesota Department of Natural Resources — This theme is a scanned and rectified version of the Minnesota DNR - Division of Waters "Public Waters Inventory" (PWI) maps. DNR Waters utilizes a small scale...

  9. Daily Weather Maps

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Several different government offices have published the Daily weather maps over its history. The publication has also gone by different names over time. The U.S....

  10. Mapping the HISS Dipole

    International Nuclear Information System (INIS)

    McParland, C.; Bieser, F.

    1984-01-01

    The principal component of the Bevalac HISS facility is a large super-conducting 3 Tesla dipole. The facility's need for a large magnetic volume spectrometer resulted in a large gap geometry - a 2 meter pole tip diameter and a 1 meter pole gap. Obviously, the field required detailed mapping for effective use as a spectrometer. The mapping device was designed with several major features in mind. The device would measure field values on a grid which described a closed rectangular solid. The grid would be a regular with the exact measurement intervals adjustable by software. The device would function unattended over the long period of time required to complete a field map. During this time, the progress of the map could be monitored by anyone with access to the HISS VAX computer. Details of the mechanical, electrical, and control design follow

  11. NOS Bathymetric Maps

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This collection of bathymetric contour maps which represent the seafloor topography includes over 400 individual titles and covers US offshore areas including Hawaii...

  12. Survey on Ontology Mapping

    Science.gov (United States)

    Zhu, Junwu

    To create a sharable semantic space in which the terms from different domain ontology or knowledge system, Ontology mapping become a hot research point in Semantic Web Community. In this paper, motivated factors of ontology mapping research are given firstly, and then 5 dominating theories and methods, such as information accessing technology, machine learning, linguistics, structure graph and similarity, are illustrated according their technology class. Before we analyses the new requirements and takes a long view, the contributions of these theories and methods are summarized in details. At last, this paper suggest to design a group of semantic connector with the ability of migration learning for OWL-2 extended with constrains and the ontology mapping theory of axiom, so as to provide a new methodology for ontology mapping.

  13. Interest rates mapping

    Science.gov (United States)

    Kanevski, M.; Maignan, M.; Pozdnoukhov, A.; Timonin, V.

    2008-06-01

    The present study deals with the analysis and mapping of Swiss franc interest rates. Interest rates depend on time and maturity, defining term structure of the interest rate curves (IRC). In the present study IRC are considered in a two-dimensional feature space-time and maturity. Exploratory data analysis includes a variety of tools widely used in econophysics and geostatistics. Geostatistical models and machine learning algorithms (multilayer perceptron and Support Vector Machines) were applied to produce interest rate maps. IR maps can be used for the visualisation and pattern perception purposes, to develop and to explore economical hypotheses, to produce dynamic asset-liability simulations and for financial risk assessments. The feasibility of an application of interest rates mapping approach for the IRC forecasting is considered as well.

  14. National Coastal Mapping Program

    Data.gov (United States)

    Army Corps of Engineers, Department of the Army, Department of Defense — The U. S. Army Corps of Engineers (USACE) National Coastal Mapping Program (NCMP) is designed to provide high-resolution elevation and imagery data along U.S....

  15. BaseMap

    Data.gov (United States)

    California Natural Resource Agency — The goal of this project is to provide a convenient base map that can be used as a starting point for CA projects. It's simple, but designed to work at a number of...

  16. Stochasticity in the Josephson map

    International Nuclear Information System (INIS)

    Nomura, Y.; Ichikawa, Y.H.; Filippov, A.T.

    1996-04-01

    The Josephson map describes nonlinear dynamics of systems characterized by standard map with the uniform external bias superposed. The intricate structures of the phase space portrait of the Josephson map are examined on the basis of the tangent map associated with the Josephson map. Numerical observation of the stochastic diffusion in the Josephson map is examined in comparison with the renormalized diffusion coefficient calculated by the method of characteristic function. The global stochasticity of the Josephson map occurs at the values of far smaller stochastic parameter than the case of the standard map. (author)

  17. Ogallala Aquifer Mapping Program

    International Nuclear Information System (INIS)

    1984-10-01

    A computerized data file has been established which can be used efficiently by the contour-plotting program SURFACE II to produce maps of the Ogallala aquifer in 17 counties of the Texas Panhandle. The data collected have been evaluated and compiled into three sets, from which SURFACE II can generate maps of well control, aquifer thickness, saturated thickness, water level, and the difference between virgin (pre-1942) and recent (1979 to 1981) water levels. 29 figures, 1 table

  18. Maps for the future.

    Directory of Open Access Journals (Sweden)

    Cristina D’Alessandro-Scarpari

    2005-05-01

    Full Text Available Geographers’ relations with maps have a long story of attraction and repulsion. The map has always fascinated Geographers (even before the institutionalization of the discipline as a powerful tool, able to demarcate territories, to produce different visions of them and to transform them by the actions they may cause or influence. Sometimes for strategic reasons Geographers have also denigrated cartography as a secondary and technical form of knowledge, a tool merely for understanding and ...

  19. Dynamics of exponential maps

    OpenAIRE

    Rempe, Lasse

    2003-01-01

    This thesis contains several new results about the dynamics of exponential maps $z\\mapsto \\exp(z)+\\kappa$. In particular, we prove that periodic external rays of exponential maps with nonescaping singular value always land. This is an analog of a theorem of Douady and Hubbard for polynomials. We also answer a question of Herman, Baker and Rippon by showing that the boundary of an unbounded exponential Siegel disk always contains the singular value. In addition to the presentation of new resul...

  20. MAPS of Cancer

    Science.gov (United States)

    Gray, Lincoln

    1998-01-01

    Our goal was to produce an interactive visualization from a mathematical model that successfully predicts metastases from head and neck cancer. We met this goal early in the project. The visualization is available for the public to view. Our work appears to fill a need for more information about this deadly disease. The idea of this project was to make an easily interpretable visualization based on what we call "functional maps" of disease. A functional map is a graphic summary of medical data, where distances between parts of the body are determined by the probability of disease, not by anatomical distances. Functional maps often beat little resemblance to anatomical maps, but they can be used to predict the spread of disease. The idea of modeling the spread of disease in an abstract multidimensional space is difficult for many people. Our goal was to make the important predictions easy to see. NASA must face this problem frequently: how to help laypersons and professionals see important trends in abstract, complex data. We took advantage of concepts perfected in NASA's graphics libraries. As an analogy, consider a functional map of early America. Suppose we choose travel times, rather than miles, as our measures of inter-city distances. For Abraham Lincoln, travel times would have been the more meaningful measure of separation between cities. In such a map New Orleans would be close to Memphis because of the Mississippi River. St. Louis would be close to Portland because of the Oregon Trail. Oklahoma City would be far from Little Rock because of the Cheyenne. Such a map would look puzzling to those of us who have always seen physical maps, but the functional map would be more useful in predicting the probabilities of inter-site transit. Continuing the analogy, we could predict the spread of social diseases such as gambling along the rivers and cattle rustling along the trails. We could simply print the functional map of America, but it would be more interesting

  1. La modélisation et le contrôle des services BigData : application à la performance et la fiabilité de MapReduce

    OpenAIRE

    Berekmeri , Mihaly

    2015-01-01

    The amount of raw data produced by everything from our mobile phones, tablets, computers to our smart watches brings novel challenges in data storage and analysis. Many solutions have arisen in the industry to treat these large quantities of raw data, the most popular being the MapReduce framework. However, while the deployment complexity of such computing systems is steadily increasing, continuous availability and fast response times are still the expected norm. Furthermore, with the advent ...

  2. Dynamic map labeling.

    Science.gov (United States)

    Been, Ken; Daiches, Eli; Yap, Chee

    2006-01-01

    We address the problem of filtering, selecting and placing labels on a dynamic map, which is characterized by continuous zooming and panning capabilities. This consists of two interrelated issues. The first is to avoid label popping and other artifacts that cause confusion and interrupt navigation, and the second is to label at interactive speed. In most formulations the static map labeling problem is NP-hard, and a fast approximation might have O(nlogn) complexity. Even this is too slow during interaction, when the number of labels shown can be several orders of magnitude less than the number in the map. In this paper we introduce a set of desiderata for "consistent" dynamic map labeling, which has qualities desirable for navigation. We develop a new framework for dynamic labeling that achieves the desiderata and allows for fast interactive display by moving all of the selection and placement decisions into the preprocessing phase. This framework is general enough to accommodate a variety of selection and placement algorithms. It does not appear possible to achieve our desiderata using previous frameworks. Prior to this paper, there were no formal models of dynamic maps or of dynamic labels; our paper introduces both. We formulate a general optimization problem for dynamic map labeling and give a solution to a simple version of the problem. The simple version is based on label priorities and a versatile and intuitive class of dynamic label placements we call "invariant point placements". Despite these restrictions, our approach gives a useful and practical solution. Our implementation is incorporated into the G-Vis system which is a full-detail dynamic map of the continental USA. This demo is available through any browser.

  3. Introduction to "Mapping Vietnameseness"

    Directory of Open Access Journals (Sweden)

    Hue-Tam Ho Tai

    2016-09-01

    Full Text Available Vietnam and China are currently engaged in a map war, with each country using ancient maps to buttress its claims to territorial sovereignty over some uninhabited islands in the South China Sea (in Chinese terminology, also known as the Eastern Sea (in Vietnamese. But what do maps in fact represent? What is meant by “territory”? How are territorial limits conceived? These questions were raised in a May 2015 workshop inspired by Thongchai Winichakul’s Siam Mapped: A History of the Geo-Body of a Nation (1994, a groundbreaking book that traces the transformation of Thai geographical consciousness as a result of Siam’s encounter with Western powers in the nineteenth century. While many of Thongchai’s insights apply to the Vietnamese case, as the first of the three articles included in this special issue of Cross-Currents shows, some of the 2015 workshop participants’ conclusions departed from his, especially regarding the formation of a Vietnamese geographical consciousness before the colonial period.[i] This is true of the other two papers, which focus specifically on the construction of borders and the associated production of maps in the nineteenth century before French colonial conquest... Notes 1 Thanks are due to the Max Planck Institute for the Study of Religious and Ethnic Change in Gottingen, Germany, for its gracious hosting and generous funding of the conference, together with the Asia Center of Harvard University.

  4. Mapping sequences by parts

    Directory of Open Access Journals (Sweden)

    Guziolowski Carito

    2007-09-01

    Full Text Available Abstract Background: We present the N-map method, a pairwise and asymmetrical approach which allows us to compare sequences by taking into account evolutionary events that produce shuffled, reversed or repeated elements. Basically, the optimal N-map of a sequence s over a sequence t is the best way of partitioning the first sequence into N parts and placing them, possibly complementary reversed, over the second sequence in order to maximize the sum of their gapless alignment scores. Results: We introduce an algorithm computing an optimal N-map with time complexity O (|s| × |t| × N using O (|s| × |t| × N memory space. Among all the numbers of parts taken in a reasonable range, we select the value N for which the optimal N-map has the most significant score. To evaluate this significance, we study the empirical distributions of the scores of optimal N-maps and show that they can be approximated by normal distributions with a reasonable accuracy. We test the functionality of the approach over random sequences on which we apply artificial evolutionary events. Practical Application: The method is illustrated with four case studies of pairs of sequences involving non-standard evolutionary events.

  5. Stochastic thermodynamics of quantum maps with and without equilibrium.

    Science.gov (United States)

    Barra, Felipe; Lledó, Cristóbal

    2017-11-01

    We study stochastic thermodynamics for a quantum system of interest whose dynamics is described by a completely positive trace-preserving (CPTP) map as a result of its interaction with a thermal bath. We define CPTP maps with equilibrium as CPTP maps with an invariant state such that the entropy production due to the action of the map on the invariant state vanishes. Thermal maps are a subgroup of CPTP maps with equilibrium. In general, for CPTP maps, the thermodynamic quantities, such as the entropy production or work performed on the system, depend on the combined state of the system plus its environment. We show that these quantities can be written in terms of system properties for maps with equilibrium. The relations that we obtain are valid for arbitrary coupling strengths between the system and the thermal bath. The fluctuations of thermodynamic quantities are considered in the framework of a two-point measurement scheme. We derive the entropy production fluctuation theorem for general maps and a fluctuation relation for the stochastic work on a system that starts in the Gibbs state. Some simplifications for the probability distributions in the case of maps with equilibrium are presented. We illustrate our results by considering spin 1/2 systems under thermal maps, nonthermal maps with equilibrium, maps with nonequilibrium steady states, and concatenations of them. Finally, and as an important application, we consider a particular limit in which the concatenation of maps generates a continuous time evolution in Lindblad form for the system of interest, and we show that the concept of maps with and without equilibrium translates into Lindblad equations with and without quantum detailed balance, respectively. The consequences for the thermodynamic quantities in this limit are discussed.

  6. Nonreference Medical Image Edge Map Measure

    Directory of Open Access Journals (Sweden)

    Karen Panetta

    2014-01-01

    Full Text Available Edge detection is a key step in medical image processing. It is widely used to extract features, perform segmentation, and further assist in diagnosis. A poor quality edge map can result in false alarms and misses in cancer detection algorithms. Therefore, it is necessary to have a reliable edge measure to assist in selecting the optimal edge map. Existing reference based edge measures require a ground truth edge map to evaluate the similarity between the generated edge map and the ground truth. However, the ground truth images are not available for medical images. Therefore, a nonreference edge measure is ideal for medical image processing applications. In this paper, a nonreference reconstruction based edge map evaluation (NREM is proposed. The theoretical basis is that a good edge map keeps the structure and details of the original image thus would yield a good reconstructed image. The NREM is based on comparing the similarity between the reconstructed image with the original image using this concept. The edge measure is used for selecting the optimal edge detection algorithm and optimal parameters for the algorithm. Experimental results show that the quantitative evaluations given by the edge measure have good correlations with human visual analysis.

  7. Necessary conditions for cartographic communication and navigation with guide maps

    OpenAIRE

    Wakabayashi, Yoshiki

    2007-01-01

    The aim of this study was to examine the necessary conditions for the communication of geographic information and navigation with guide maps by conducting two experiments. The results of the first experiment showed that not only local landmarks but also the names of well-known places were necessary to identify the location indicated by the map. The spatial abilities of the subject also affected the performance of the identification task when the map indicated unfamiliar places. The second exp...

  8. The evolving Alaska mapping program.

    Science.gov (United States)

    Brooks, P.D.; O'Brien, T. J.

    1986-01-01

    This paper describes the development of mapping in Alaska, the current status of the National Mapping Program, and future plans for expanding and improving the mapping coverage. Research projects with Landsat Multispectral Scanner and Return Vidicon imagery and real- and synthetic-aperture radar; image mapping programs; digital mapping; remote sensing projects; the Alaska National Interest Lands Conservation Act; and the Alaska High-Altitude Aerial Photography Program are also discussed.-from Authors

  9. Ergodicity of polygonal slap maps

    International Nuclear Information System (INIS)

    Del Magno, Gianluigi; Pedro Gaivão, José; Lopes Dias, João; Duarte, Pedro

    2014-01-01

    Polygonal slap maps are piecewise affine expanding maps of the interval obtained by projecting the sides of a polygon along their normals onto the perimeter of the polygon. These maps arise in the study of polygonal billiards with non-specular reflection laws. We study the absolutely continuous invariant probabilities (acips) of the slap maps for several polygons, including regular polygons and triangles. We also present a general method for constructing polygons with slap maps with more than one ergodic acip. (paper)

  10. Mapping Unknown Knowns

    DEFF Research Database (Denmark)

    Diogo de Andrade Silva, Elisa; Lanng, Ditte Bendix; Wind, Simon

    representative dimensions of travellers’ embodied ‘dwelling-in-motion’ (Urry, 2007) and experiences. The paper foregrounds a ‘Mapping-in-Motion’ graphic example, an experimental urban design student assignment aiming to map some of the less representative dimensions of journeys between A and B in Berlin...... in relation to analysis, representation, exploration and design of everyday travelling in the city. Such ‘mobilities design’ (Jensen and Lanng 2017) concerns routes, sites and artefacts of mobilities, e.g., road networks, train stations, and bike parking facilities. Some dimensions of these structures...

  11. Learning Bing maps API

    CERN Document Server

    Sinani, Artan

    2013-01-01

    This is a practical, hands-on guide with illustrative examples, which will help you explore the vast universe of Bing maps.If you are a developer who wants to learn how to exploit the numerous features of Bing Maps then this book is ideal for you. It can also be useful for more experienced developers who wish to explore other areas of the APIs. It is assumed that you have some knowledge of JavaScript, HTML, and CSS. For some chapters a working knowledge of .Net and Visual Studio is also needed.

  12. Graphene Conductance Uniformity Mapping

    DEFF Research Database (Denmark)

    Buron, Jonas Christian Due; Petersen, Dirch Hjorth; Bøggild, Peter

    2012-01-01

    We demonstrate a combination of micro four-point probe (M4PP) and non-contact terahertz time-domain spectroscopy (THz-TDS) measurements for centimeter scale quantitative mapping of the sheet conductance of large area chemical vapor deposited graphene films. Dual configuration M4PP measurements......, demonstrated on graphene for the first time, provide valuable statistical insight into the influence of microscale defects on the conductance, while THz-TDS has potential as a fast, non-contact metrology method for mapping of the spatially averaged nanoscopic conductance on wafer-scale graphene with scan times......, dominating the microscale conductance of the investigated graphene film....

  13. cudaMap: a GPU accelerated program for gene expression connectivity mapping.

    Science.gov (United States)

    McArt, Darragh G; Bankhead, Peter; Dunne, Philip D; Salto-Tellez, Manuel; Hamilton, Peter; Zhang, Shu-Dong

    2013-10-11

    Modern cancer research often involves large datasets and the use of sophisticated statistical techniques. Together these add a heavy computational load to the analysis, which is often coupled with issues surrounding data accessibility. Connectivity mapping is an advanced bioinformatic and computational technique dedicated to therapeutics discovery and drug re-purposing around differential gene expression analysis. On a normal desktop PC, it is common for the connectivity mapping task with a single gene signature to take > 2h to complete using sscMap, a popular Java application that runs on standard CPUs (Central Processing Units). Here, we describe new software, cudaMap, which has been implemented using CUDA C/C++ to harness the computational power of NVIDIA GPUs (Graphics Processing Units) to greatly reduce processing times for connectivity mapping. cudaMap can identify candidate therapeutics from the same signature in just over thirty seconds when using an NVIDIA Tesla C2050 GPU. Results from the analysis of multiple gene signatures, which would previously have taken several days, can now be obtained in as little as 10 minutes, greatly facilitating candidate therapeutics discovery with high throughput. We are able to demonstrate dramatic speed differentials between GPU assisted performance and CPU executions as the computational load increases for high accuracy evaluation of statistical significance. Emerging 'omics' technologies are constantly increasing the volume of data and information to be processed in all areas of biomedical research. Embracing the multicore functionality of GPUs represents a major avenue of local accelerated computing. cudaMap will make a strong contribution in the discovery of candidate therapeutics by enabling speedy execution of heavy duty connectivity mapping tasks, which are increasingly required in modern cancer research. cudaMap is open source and can be freely downloaded from http://purl.oclc.org/NET/cudaMap.

  14. Mapping shape to visuomotor mapping: learning and generalisation of sensorimotor behaviour based on contextual information.

    Directory of Open Access Journals (Sweden)

    Loes C J van Dam

    2015-03-01

    Full Text Available Humans can learn and store multiple visuomotor mappings (dual-adaptation when feedback for each is provided alternately. Moreover, learned context cues associated with each mapping can be used to switch between the stored mappings. However, little is known about the associative learning between cue and required visuomotor mapping, and how learning generalises to novel but similar conditions. To investigate these questions, participants performed a rapid target-pointing task while we manipulated the offset between visual feedback and movement end-points. The visual feedback was presented with horizontal offsets of different amounts, dependent on the targets shape. Participants thus needed to use different visuomotor mappings between target location and required motor response depending on the target shape in order to "hit" it. The target shapes were taken from a continuous set of shapes, morphed between spiky and circular shapes. After training we tested participants performance, without feedback, on different target shapes that had not been learned previously. We compared two hypotheses. First, we hypothesised that participants could (explicitly extract the linear relationship between target shape and visuomotor mapping and generalise accordingly. Second, using previous findings of visuomotor learning, we developed a (implicit Bayesian learning model that predicts generalisation that is more consistent with categorisation (i.e. use one mapping or the other. The experimental results show that, although learning the associations requires explicit awareness of the cues' role, participants apply the mapping corresponding to the trained shape that is most similar to the current one, consistent with the Bayesian learning model. Furthermore, the Bayesian learning model predicts that learning should slow down with increased numbers of training pairs, which was confirmed by the present results. In short, we found a good correspondence between the

  15. Constructing a Soil Class Map of Denmark based on the FAO Legend Using Digital Techniques

    DEFF Research Database (Denmark)

    Adhikari, Kabindra; Minasny, Budiman; Greve, Mette Balslev

    2014-01-01

    Soil mapping in Denmark has a long history and a series of soil maps based on conventional mapping approaches have been produced. In this study, a national soil map of Denmark was constructed based on the FAO–Unesco Revised Legend 1990 using digital soil mapping techniques, existing soil profile......) confirmed that the output is reliable and can be used in various soil and environmental studies without major difficulties. This study also verified the importance of GlobalSoilMap products and a priori pedological information that improved prediction performance and quality of the new FAO soil map...

  16. Quantitative X-ray mapping, scatter diagrams and the generation of correction maps to obtain more information about your material

    Science.gov (United States)

    Wuhrer, R.; Moran, K.

    2014-03-01

    Quantitative X-ray mapping with silicon drift detectors and multi-EDS detector systems have become an invaluable analysis technique and one of the most useful methods of X-ray microanalysis today. The time to perform an X-ray map has reduced considerably with the ability to map minor and trace elements very accurately due to the larger detector area and higher count rate detectors. Live X-ray imaging can now be performed with a significant amount of data collected in a matter of minutes. A great deal of information can be obtained from X-ray maps. This includes; elemental relationship or scatter diagram creation, elemental ratio mapping, chemical phase mapping (CPM) and quantitative X-ray maps. In obtaining quantitative x-ray maps, we are able to easily generate atomic number (Z), absorption (A), fluorescence (F), theoretical back scatter coefficient (η), and quantitative total maps from each pixel in the image. This allows us to generate an image corresponding to each factor (for each element present). These images allow the user to predict and verify where they are likely to have problems in our images, and are especially helpful to look at possible interface artefacts. The post-processing techniques to improve the quantitation of X-ray map data and the development of post processing techniques for improved characterisation are covered in this paper.

  17. Quantitative X-ray mapping, scatter diagrams and the generation of correction maps to obtain more information about your material

    International Nuclear Information System (INIS)

    Wuhrer, R; Moran, K

    2014-01-01

    Quantitative X-ray mapping with silicon drift detectors and multi-EDS detector systems have become an invaluable analysis technique and one of the most useful methods of X-ray microanalysis today. The time to perform an X-ray map has reduced considerably with the ability to map minor and trace elements very accurately due to the larger detector area and higher count rate detectors. Live X-ray imaging can now be performed with a significant amount of data collected in a matter of minutes. A great deal of information can be obtained from X-ray maps. This includes; elemental relationship or scatter diagram creation, elemental ratio mapping, chemical phase mapping (CPM) and quantitative X-ray maps. In obtaining quantitative x-ray maps, we are able to easily generate atomic number (Z), absorption (A), fluorescence (F), theoretical back scatter coefficient (η), and quantitative total maps from each pixel in the image. This allows us to generate an image corresponding to each factor (for each element present). These images allow the user to predict and verify where they are likely to have problems in our images, and are especially helpful to look at possible interface artefacts. The post-processing techniques to improve the quantitation of X-ray map data and the development of post processing techniques for improved characterisation are covered in this paper

  18. Hardmetals - microstructural design, testing and property maps

    Energy Technology Data Exchange (ETDEWEB)

    Roebuck, B; Gee, M G; Morrell, R [NPL Materials Centre, National Physical Laboratory, Teddington, Middlesex (United Kingdom)

    2001-07-01

    The production of WC/Co hardmetals and their analogues is considered a mature technology, however lately there has been new research results where the concept of microstructural design was used to produce alternatives to the conventional two-phase structure. This Industry is currently well served by a range of baseline established standards, which, if properly followed with good attention to correct quality procedures, will ensure consistent products. However, there are certain key properties such as corrosion, fatigue, impact wear or high temperature strength and toughness that are often measured but not always by standard tests methods. Microstructural design potential is reviewed, particularly the possibilities of performance improvement via changes in size, shape and distribution of the phases as well as recent developments in testing, specifically S-N fatigue and abrasive wear. Finally, the concept of property mapping is introduced as a tool for providing a framework for optimizing properties. Its utility in correlating performance properties and their relationships with microstructural parameters is evaluated. Two property maps are discussed: one where the property is plotted against a microstructural feature (microstructure property maps) such as WC grain size or Co binder phase content against coercivity or hardness and one where different properties, such as hardness and toughness are mapped against each other (comparative property maps). (nevyjel)

  19. Hardmetals - microstructural design, testing and property maps

    International Nuclear Information System (INIS)

    Roebuck, B.; Gee, M.G.; Morrell, R.

    2001-01-01

    The production of WC/Co hardmetals and their analogues is considered a mature technology, however lately there has been new research results where the concept of microstructural design was used to produce alternatives to the conventional two-phase structure. This Industry is currently well served by a range of baseline established standards, which, if properly followed with good attention to correct quality procedures, will ensure consistent products. However, there are certain key properties such as corrosion, fatigue, impact wear or high temperature strength and toughness that are often measured but not always by standard tests methods. Microstructural design potential is reviewed, particularly the possibilities of performance improvement via changes in size, shape and distribution of the phases as well as recent developments in testing, specifically S-N fatigue and abrasive wear. Finally, the concept of property mapping is introduced as a tool for providing a framework for optimizing properties. Its utility in correlating performance properties and their relationships with microstructural parameters is evaluated. Two property maps are discussed: one where the property is plotted against a microstructural feature (microstructure property maps) such as WC grain size or Co binder phase content against coercivity or hardness and one where different properties, such as hardness and toughness are mapped against each other (comparative property maps). (nevyjel)

  20. 78 FR 65689 - Technical Mapping Advisory Council

    Science.gov (United States)

    2013-11-01

    ... data; and performance metrics and milestones required to effectively and efficiently map flood risk... incorporate the best available climate science to assess flood risks and ensure that FEMA uses the best... Government Employees (SGE) as defined in section 202(a) of title 18 United States Code. Candidates selected...

  1. Efficient Bit-to-Symbol Likelihood Mappings

    Science.gov (United States)

    Moision, Bruce E.; Nakashima, Michael A.

    2010-01-01

    This innovation is an efficient algorithm designed to perform bit-to-symbol and symbol-to-bit likelihood mappings that represent a significant portion of the complexity of an error-correction code decoder for high-order constellations. Recent implementation of the algorithm in hardware has yielded an 8- percent reduction in overall area relative to the prior design.

  2. 2004 Alaska Lidar Mapping

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The data sets are generated using the OPTECH ALTM 70 kHz LIDAR system mounted onboard AeroMap's twin-engine Cessna 320 aircraft. Classified data sets such as this...

  3. Ramachandran and his Map

    Indian Academy of Sciences (India)

    Ramachandran map, detailed in this article. His current interests are peptide, cyclic peptide and protein conforma- tions, energetics, data analysis, computer modeling as well as development of new algorithms useful for the conformational studies. C Ramakrishnan. Introduction. Professor G N Ramachandran was one of the ...

  4. Photogrammetry and Digital Mapping

    DEFF Research Database (Denmark)

    Frederiksen, Poul

    1998-01-01

    Technical tour to Lithuania, Poland and Estonia for 13 technical staff and managers of State Land Service, HQ, Latvia. Focus on technical aspects and management of geographical data for map production and administration. Visits to state and local government organisations and newly established...

  5. Mapping World Hunger.

    Science.gov (United States)

    Van Vliet, Lucille W.

    1988-01-01

    Describes a lesson designed to involve students in grades 6 through 8 in learning how geography was affected the problem of world hunger. Emphasis is placed on using maps, globes, atlases, and geographic dictionaries, as well as books, magazines, and other resources. (MES)

  6. Fluence map segmentation

    International Nuclear Information System (INIS)

    Rosenwald, J.-C.

    2008-01-01

    The lecture addressed the following topics: 'Interpreting' the fluence map; The sequencer; Reasons for difference between desired and actual fluence map; Principle of 'Step and Shoot' segmentation; Large number of solutions for given fluence map; Optimizing 'step and shoot' segmentation; The interdigitation constraint; Main algorithms; Conclusions on segmentation algorithms (static mode); Optimizing intensity levels and monitor units; Sliding window sequencing; Synchronization to avoid the tongue-and-groove effect; Accounting for physical characteristics of MLC; Importance of corrections for leaf transmission and offset; Accounting for MLC mechanical constraints; The 'complexity' factor; Incorporating the sequencing into optimization algorithm; Data transfer to the treatment machine; Interface between R and V and accelerator; and Conclusions on fluence map segmentation (Segmentation is part of the overall inverse planning procedure; 'Step and Shoot' and 'Dynamic' options are available for most TPS (depending on accelerator model; The segmentation phase tends to come into the optimization loop; The physical characteristics of the MLC have a large influence on final dose distribution; The IMRT plans (MU and relative dose distribution) must be carefully validated). (P.A.)

  7. Mapping the Heavens

    Indian Academy of Sciences (India)

    results of astrophysical mapping along multi- ple dimensions of space and time that deter- mine the distribution ... discipline, the book evocatively charts out the enormous impact of these advances on human culture, in that our ... And her evocative writing skills make the de- scriptions of these various discoveries come alive.

  8. Bike Map Lines

    Data.gov (United States)

    Town of Chapel Hill, North Carolina — Chapel Hill Bike Map Lines from KMZ file.This data came from the wiki comment board for the public, not an “official map” showing the Town of Chapel Hill's plans or...

  9. Copenhagen Sonic Experience Map

    DEFF Research Database (Denmark)

    Kreutzfeldt, Jacob

    2011-01-01

    In the wake of present European interest for mapping urban noise, it seems increasingly relevant to investigate the multiple ways in which sound intersects with the everyday experiences of urban citizens. Focusing on the polluting effects of infrastructural noise, the EU-initiated project of asse...

  10. Extending Lipschitz mappings continuously

    Czech Academy of Sciences Publication Activity Database

    Kopecká, Eva

    2012-01-01

    Roč. 18, č. 2 (2012), s. 167-177 ISSN 1425-6908 Institutional support: RVO:67985840 Keywords : Lipschitz mapping * Hilbert space * extension Subject RIV: BA - General Mathematics http://www.degruyter.com/view/j/jaa.2012.18.issue-2/jaa-2012-0011/jaa-2012-0011. xml

  11. STOCHASTIC FLOWS OF MAPPINGS

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    In this paper, the stochastic flow of mappings generated by a Feller convolution semigroup on a compact metric space is studied. This kind of flow is the generalization of superprocesses of stochastic flows and stochastic diffeomorphism induced by the strong solutions of stochastic differential equations.

  12. Mapping the Literature

    DEFF Research Database (Denmark)

    Boulus-Rødje, Nina

    2012-01-01

    As the utilization of various e-voting technologies has notably increased in the past few years, so has the amount of publications on experiences with these technologies. This article, will, therefore map the literature while highlighting some of the important topics discussed within the field of e...

  13. Mapping functional connectivity

    Science.gov (United States)

    Peter Vogt; Joseph R. Ferrari; Todd R. Lookingbill; Robert H. Gardner; Kurt H. Riitters; Katarzyna Ostapowicz

    2009-01-01

    An objective and reliable assessment of wildlife movement is important in theoretical and applied ecology. The identification and mapping of landscape elements that may enhance functional connectivity is usually a subjective process based on visual interpretations of species movement patterns. New methods based on mathematical morphology provide a generic, flexible,...

  14. Historical Topographic Map Collection bookmark

    Science.gov (United States)

    Fishburn, Kristin A.; Allord, Gregory J.

    2017-06-29

    The U.S. Geological Survey (USGS) National Geospatial Program is scanning published USGS 1:250,000-scale and larger topographic maps printed between 1884, the inception of the topographic mapping program, and 2006. The goal of this project, which began publishing the historical scanned maps in 2011, is to provide a digital repository of USGS topographic maps, available to the public at no cost. For more than 125 years, USGS topographic maps have accurately portrayed the complex geography of the Nation. The USGS is the Nation’s largest producer of printed topographic maps, and prior to 2006, USGS topographic maps were created using traditional cartographic methods and printed using a lithographic printing process. As the USGS continues the release of a new generation of topographic maps (US Topo) in electronic form, the topographic map remains an indispensable tool for government, science, industry, land management planning, and leisure.

  15. Generalized Smooth Transition Map Between Tent and Logistic Maps

    Science.gov (United States)

    Sayed, Wafaa S.; Fahmy, Hossam A. H.; Rezk, Ahmed A.; Radwan, Ahmed G.

    There is a continuous demand on novel chaotic generators to be employed in various modeling and pseudo-random number generation applications. This paper proposes a new chaotic map which is a general form for one-dimensional discrete-time maps employing the power function with the tent and logistic maps as special cases. The proposed map uses extra parameters to provide responses that fit multiple applications for which conventional maps were not enough. The proposed generalization covers also maps whose iterative relations are not based on polynomials, i.e. with fractional powers. We introduce a framework for analyzing the proposed map mathematically and predicting its behavior for various combinations of its parameters. In addition, we present and explain the transition map which results in intermediate responses as the parameters vary from their values corresponding to tent map to those corresponding to logistic map case. We study the properties of the proposed map including graph of the map equation, general bifurcation diagram and its key-points, output sequences, and maximum Lyapunov exponent. We present further explorations such as effects of scaling, system response with respect to the new parameters, and operating ranges other than transition region. Finally, a stream cipher system based on the generalized transition map validates its utility for image encryption applications. The system allows the construction of more efficient encryption keys which enhances its sensitivity and other cryptographic properties.

  16. Using Digital Mapping Tool in Ill-Structured Problem Solving

    Science.gov (United States)

    Bai, Hua

    2013-01-01

    Scaffolding students' problem solving and helping them to improve problem solving skills are critical in instructional design courses. This study investigated the effects of students' uses of a digital mapping tool on their problem solving performance in a design case study. It was found that the students who used the digital mapping tool…

  17. When Reasoning Modifies Memory: Schematic Assimilation Triggered by Analogical Mapping

    Science.gov (United States)

    Vendetti, Michael S.; Wu, Aaron; Rowshanshad, Ebi; Knowlton, Barbara J.; Holyoak, Keith J.

    2014-01-01

    Analogical mapping highlights shared relations that link 2 situations, potentially at the expense of information that does not fit the dominant pattern of correspondences. To investigate whether analogical mapping can alter subsequent recognition memory for features of a source analog, we performed 2 experiments with 4-term proportional analogies…

  18. PSO algorithm enhanced with Lozi Chaotic Map - Tuning experiment

    Energy Technology Data Exchange (ETDEWEB)

    Pluhacek, Michal; Senkerik, Roman; Zelinka, Ivan [Tomas Bata University in Zlín, Faculty of Applied Informatics Department of Informatics and Artificial Intelligence nám. T.G. Masaryka 5555, 760 01 Zlín (Czech Republic)

    2015-03-10

    In this paper it is investigated the effect of tuning of control parameters of the Lozi Chaotic Map employed as a chaotic pseudo-random number generator for the particle swarm optimization algorithm. Three different benchmark functions are selected from the IEEE CEC 2013 competition benchmark set. The Lozi map is extensively tuned and the performance of PSO is evaluated.

  19. A Developmental Mapping Program Integrating Geography and Mathematics.

    Science.gov (United States)

    Muir, Sharon Pray; Cheek, Helen Neely

    Presented and discussed is a model which can be used by educators who want to develop an interdisciplinary map skills program in geography and mathematics. The model assumes that most children in elementary schools perform cognitively at Piaget's concrete operational stage, that readiness for map skills can be assessed with Piagetian or…

  20. PSO algorithm enhanced with Lozi Chaotic Map - Tuning experiment

    International Nuclear Information System (INIS)

    Pluhacek, Michal; Senkerik, Roman; Zelinka, Ivan

    2015-01-01

    In this paper it is investigated the effect of tuning of control parameters of the Lozi Chaotic Map employed as a chaotic pseudo-random number generator for the particle swarm optimization algorithm. Three different benchmark functions are selected from the IEEE CEC 2013 competition benchmark set. The Lozi map is extensively tuned and the performance of PSO is evaluated

  1. USGS Imagery Only Base Map Service from The National Map

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — USGS Imagery Only is a tile cache base map of orthoimagery in The National Map visible to the 1:18,000 scale. Orthoimagery data are typically high resolution images...

  2. Inland excess water mapping using hyperspectral imagery

    Directory of Open Access Journals (Sweden)

    Csendes Bálint

    2016-01-01

    Full Text Available Hyperspectral imaging combined with the potentials of airborne scanning is a powerful tool to monitor environmental processes. The aim of this research was to use high resolution remotely sensed data to map the spatial extent of inland excess water patches in a Hungarian study area that is known for its oil and gas production facilities. Periodic floodings show high spatial and temporal variability, nevertheless, former studies have proven that the affected soil surfaces can be accurately identified. Besides separability measurements, we performed spectral angle classification, which gave a result of 85% overall accuracy and we also compared the generated land cover map with LIDAR elevation data.

  3. Runs of homozygosity implicate autozygosity as a schizophrenia risk factor

    DEFF Research Database (Denmark)

    Keller, Matthew C; Simonson, Matthew A; Ripke, Stephan

    2012-01-01

    Autozygosity occurs when two chromosomal segments that are identical from a common ancestor are inherited from each parent. This occurs at high rates in the offspring of mates who are closely related (inbreeding), but also occurs at lower levels among the offspring of distantly related mates. Her...

  4. Phenotypic expressions of CCR5-Delta 32/Delta 32 homozygosity

    NARCIS (Netherlands)

    Nguyen, GT; Carrington, M; Beeler, JA; Dean, M; Aledort, LM; Blatt, PM; Cohen, AR; DiMichele, D; Eyster, ME; Kessler, CM; Konkle, B; Leissinger, C; Luban, N; O'Brien, SJ; Goedert, JJ; O'Brien, TR

    1999-01-01

    Objective: As blockade of CC-chemokine receptor 5 (CCR5) has been proposed as therapy for HIV-1, we examined whether the CCR5-Delta 32/Delta 32 homozygous genotype has phenotypic expressions other than those related to HIV-1. Design: Study subjects were white homosexual men or men with hemophilia

  5. Screening for homozygosity by descent in families with autosomal ...

    Indian Academy of Sciences (India)

    Unknown

    gressive, and by adulthood constriction and gradual loss ... noids, (d) transcription factors important for photorece- ptors, (e) .... Unconventional myosin present in photoreceptors and hair cells of ... Functions in isomerization of vitamin A in RPE.

  6. Optimization of friction stir welding using space mapping and manifold mapping-an initial study of thermal aspects

    DEFF Research Database (Denmark)

    Larsen, Anders Astrup; Bendsøe, Martin P.; Hattel, Jesper Henri

    2009-01-01

    The aim of this paper is to optimize a thermal model of a friction stir welding process by finding optimal welding parameters. The optimization is performed using space mapping and manifold mapping techniques in which a coarse model is used along with the fine model to be optimized. Different...

  7. Mapping innovation processes: Visual techniques for opening and presenting the black box of service innovation processes

    DEFF Research Database (Denmark)

    Olesen, Anne Rørbæk

    2017-01-01

    This chapter argues for the usefulness of visual mapping techniques for performing qualitative analysis of complex service innovation processes. Different mapping formats are presented, namely, matrices, networks, process maps, situational analysis maps and temporal situational analysis maps....... For the purpose of researching service innovation processes, the three latter formats are argued to be particularly interesting. Process maps can give an overview of different periods and milestones in a process in one carefully organized location. Situational analysis maps and temporal situational analysis maps...... can open up complexities of service innovation processes, as well as close them down for presentational purposes. The mapping formats presented are illustrated by displaying maps from an exemplary research project, and the chapter is concluded with a brief discussion of the limitations and pitfalls...

  8. A Systematic Approach to Modified BCJR MAP Algorithms for Convolutional Codes

    Directory of Open Access Journals (Sweden)

    Patenaude François

    2006-01-01

    Full Text Available Since Berrou, Glavieux and Thitimajshima published their landmark paper in 1993, different modified BCJR MAP algorithms have appeared in the literature. The existence of a relatively large number of similar but different modified BCJR MAP algorithms, derived using the Markov chain properties of convolutional codes, naturally leads to the following questions. What is the relationship among the different modified BCJR MAP algorithms? What are their relative performance, computational complexities, and memory requirements? In this paper, we answer these questions. We derive systematically four major modified BCJR MAP algorithms from the BCJR MAP algorithm using simple mathematical transformations. The connections between the original and the four modified BCJR MAP algorithms are established. A detailed analysis of the different modified BCJR MAP algorithms shows that they have identical computational complexities and memory requirements. Computer simulations demonstrate that the four modified BCJR MAP algorithms all have identical performance to the BCJR MAP algorithm.

  9. Radiological maps for Trabzon, Turkey

    International Nuclear Information System (INIS)

    Kurnaz, A.; Kucukomeroglu, B.; Damla, N.; Cevik, U.

    2011-01-01

    The activity concentrations and absorbed gamma dose rates due to primordial radionuclides and 137 Cs have been ascertained in 222 soil samples in 18 counties of the Trabzon province of Turkey using a HPGe detector. The mean activity concentrations of 238 U, 232 Th, 40 K and 137 Cs in soil samples were 41, 35, 437 and 21 Bq kg -1 , respectively. Based on the measured concentrations of these radionuclides, the mean absorbed gamma dose in air was calculated as 59 nGy h -1 and hence, the mean annual effective dose due to terrestrial gamma radiation was calculated as 72 μSv y -1 . In addition, outdoor in situ gamma dose rate (D) measurements were performed in the same 222 locations using a portable NaI detector and the annual effective dose was calculated to be 66 μSv y -1 from these results. The results presented in this study are compared with other parts of Turkey. Radiological maps of the Trabzon province were composed using the results obtained from the study. - Highlights: → →The study highlights activity concentrations of 238 U, 232 Th, 40 K and 137 Cs in soil. → The absorbed gamma dose in air and the mean annual effective dose were calculated. → The calculated results compared with outdoor in situ gamma dose measurements. → Radiological maps of the Trabzon province were created using ArcGIS applications. → The results will be valuable data for future estimations of radioactive pollution.

  10. Objective and Comprehensive Evaluation of Bisulfite Short Read Mapping Tools

    Directory of Open Access Journals (Sweden)

    Hong Tran

    2014-01-01

    Full Text Available Background. Large-scale bisulfite treatment and short reads sequencing technology allow comprehensive estimation of methylation states of Cs in the genomes of different tissues, cell types, and developmental stages. Accurate characterization of DNA methylation is essential for understanding genotype phenotype association, gene and environment interaction, diseases, and cancer. Aligning bisulfite short reads to a reference genome has been a challenging task. We compared five bisulfite short read mapping tools, BSMAP, Bismark, BS-Seeker, BiSS, and BRAT-BW, representing two classes of mapping algorithms (hash table and suffix/prefix tries. We examined their mapping efficiency (i.e., the percentage of reads that can be mapped to the genomes, usability, running time, and effects of changing default parameter settings using both real and simulated reads. We also investigated how preprocessing data might affect mapping efficiency. Conclusion. Among the five programs compared, in terms of mapping efficiency, Bismark performs the best on the real data, followed by BiSS, BSMAP, and finally BRAT-BW and BS-Seeker with very similar performance. If CPU time is not a constraint, Bismark is a good choice of program for mapping bisulfite treated short reads. Data quality impacts a great deal mapping efficiency. Although increasing the number of mismatches allowed can increase mapping efficiency, it not only significantly slows down the program, but also runs the risk of having increased false positives. Therefore, users should carefully set the related parameters depending on the quality of their sequencing data.

  11. Brain mapping in tumors: intraoperative or extraoperative?

    Science.gov (United States)

    Duffau, Hugues

    2013-12-01

    In nontumoral epilepsy surgery, the main goal for all preoperative investigation is to first determine the epileptogenic zone, and then to analyze its relation to eloquent cortex, in order to control seizures while avoiding adverse postoperative neurologic outcome. To this end, in addition to neuropsychological assessment, functional neuroimaging and scalp electroencephalography, extraoperative recording, and electrical mapping, especially using subdural strip- or grid-electrodes, has been reported extensively. Nonetheless, in tumoral epilepsy surgery, the rationale is different. Indeed, the first aim is rather to maximize the extent of tumor resection while minimizing postsurgical morbidity, in order to increase the median survival as well as to preserve quality of life. As a consequence, as frequently seen in infiltrating tumors such as gliomas, where these lesions not only grow but also migrate along white matter tracts, the resection should be performed according to functional boundaries both at cortical and subcortical levels. With this in mind, extraoperative mapping by strips/grids is often not sufficient in tumoral surgery, since in essence, it allows study of the cortex but cannot map subcortical pathways. Therefore, intraoperative electrostimulation mapping, especially in awake patients, is more appropriate in tumor surgery, because this technique allows real-time detection of areas crucial for cerebral functions--eloquent cortex and fibers--throughout the resection. In summary, rather than choosing one or the other of different mapping techniques, methodology should be adapted to each pathology, that is, extraoperative mapping in nontumoral epilepsy surgery and intraoperative mapping in tumoral surgery. Wiley Periodicals, Inc. © 2013 International League Against Epilepsy.

  12. Projection Mapping User Interface for Disabled People.

    Science.gov (United States)

    Gelšvartas, Julius; Simutis, Rimvydas; Maskeliūnas, Rytis

    2018-01-01

    Difficulty in communicating is one of the key challenges for people suffering from severe motor and speech disabilities. Often such person can communicate and interact with the environment only using assistive technologies. This paper presents a multifunctional user interface designed to improve communication efficiency and person independence. The main component of this interface is a projection mapping technique used to highlight objects in the environment. Projection mapping makes it possible to create a natural augmented reality information presentation method. The user interface combines a depth sensor and a projector to create camera-projector system. We provide a detailed description of camera-projector system calibration procedure. The described system performs tabletop object detection and automatic projection mapping. Multiple user input modalities have been integrated into the multifunctional user interface. Such system can be adapted to the needs of people with various disabilities.

  13. Topological mappings of video and audio data.

    Science.gov (United States)

    Fyfe, Colin; Barbakh, Wesam; Ooi, Wei Chuan; Ko, Hanseok

    2008-12-01

    We review a new form of self-organizing map which is based on a nonlinear projection of latent points into data space, identical to that performed in the Generative Topographic Mapping (GTM).(1) But whereas the GTM is an extension of a mixture of experts, this model is an extension of a product of experts.(2) We show visualisation and clustering results on a data set composed of video data of lips uttering 5 Korean vowels. Finally we note that we may dispense with the probabilistic underpinnings of the product of experts and derive the same algorithm as a minimisation of mean squared error between the prototypes and the data. This leads us to suggest a new algorithm which incorporates local and global information in the clustering. Both ot the new algorithms achieve better results than the standard Self-Organizing Map.

  14. Projection Mapping User Interface for Disabled People

    Science.gov (United States)

    Simutis, Rimvydas; Maskeliūnas, Rytis

    2018-01-01

    Difficulty in communicating is one of the key challenges for people suffering from severe motor and speech disabilities. Often such person can communicate and interact with the environment only using assistive technologies. This paper presents a multifunctional user interface designed to improve communication efficiency and person independence. The main component of this interface is a projection mapping technique used to highlight objects in the environment. Projection mapping makes it possible to create a natural augmented reality information presentation method. The user interface combines a depth sensor and a projector to create camera-projector system. We provide a detailed description of camera-projector system calibration procedure. The described system performs tabletop object detection and automatic projection mapping. Multiple user input modalities have been integrated into the multifunctional user interface. Such system can be adapted to the needs of people with various disabilities. PMID:29686827

  15. Projection Mapping User Interface for Disabled People

    Directory of Open Access Journals (Sweden)

    Julius Gelšvartas

    2018-01-01

    Full Text Available Difficulty in communicating is one of the key challenges for people suffering from severe motor and speech disabilities. Often such person can communicate and interact with the environment only using assistive technologies. This paper presents a multifunctional user interface designed to improve communication efficiency and person independence. The main component of this interface is a projection mapping technique used to highlight objects in the environment. Projection mapping makes it possible to create a natural augmented reality information presentation method. The user interface combines a depth sensor and a projector to create camera-projector system. We provide a detailed description of camera-projector system calibration procedure. The described system performs tabletop object detection and automatic projection mapping. Multiple user input modalities have been integrated into the multifunctional user interface. Such system can be adapted to the needs of people with various disabilities.

  16. Mapping and characterization of LCA networks

    DEFF Research Database (Denmark)

    Bjørn, Anders; Owsianiak, Mikolaj; Laurent, Alexis

    2013-01-01

    Purpose: The aims of this study were to provide an up-todate overview of global, regional and local networks supporting life cycle thinking and to characterize them according to their structure and activities. Methods: Following a tentative life cycle assessment (LCA) network definition, a mapping......: The provided list of LCA networks is currently the most comprehensive, publicly available mapping. We believe that the results of this mapping can serve as a basis for deciding where priorities should be set to increase the dissemination and development of LCA worldwide. In this aim, we also advocate...... was performed based on (1) a literature search, (2) a web search and (3) an inquiry to stakeholders distributed via the two largest LCA fora. Networks were characterized based on responses from a survey. Results and discussion: We identified 100 networks, of which 29 fulfilled all six criteria composing our...

  17. Letters of Map Change (LOMC)

    Data.gov (United States)

    Department of Homeland Security — Documents, including different types of Letters of MAP Revision (LOMR) and Letters of Map Amendment (LOMA), which are issued by FEMA to revise or amend the flood...

  18. NEPR Geographic Zone Map 2015

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This geographic zone map was created by interpreting satellite and aerial imagery, seafloor topography (bathymetry model), and the new NEPR Benthic Habitat Map...

  19. NEPR Benthic Habitat Map 2015

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This benthic habitat map was created from a semi-automated habitat mapping process, using a combination of bathymetry, satellite imagery, aerial imagery and...

  20. q-Deformed nonlinear maps

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics; Volume 64; Issue 3 ... Keywords. Nonlinear dynamics; logistic map; -deformation; Tsallis statistics. ... As a specific example, a -deformation procedure is applied to the logistic map. Compared ...

  1. The Europa Global Geologic Map

    Science.gov (United States)

    Leonard, E. J.; Patthoff, D. A.; Senske, D. A.; Collins, G. C.

    2018-06-01

    The Europa Global Geologic Map reveals three periods in Europa's surface history as well as an interesting distribution of microchaos. We will discuss the mapping and the interesting implications of our analysis of Europa's surface.

  2. Map projections cartographic information systems

    CERN Document Server

    Grafarend, Erik W; Syffus, Rainer

    2014-01-01

    This book offers a timely review of map projections including sphere, ellipsoid, rotational surfaces, and geodetic datum transformations. Coverage includes computer vision, and remote sensing space projective mappings in photogrammetry.

  3. Map projections cartographic information systems

    CERN Document Server

    Grafarend, Erik W

    2006-01-01

    In the context of Geographical Information Systems (GIS) the book offers a timely review of map projections (sphere, ellipsoid, rotational surfaces) and geodetic datum transformations. For the needs of photogrammetry, computer vision, and remote sensing space projective mappings are reviewed.

  4. Universal map for cellular automata

    International Nuclear Information System (INIS)

    García-Morales, V.

    2012-01-01

    A universal map is derived for all deterministic 1D cellular automata (CAs) containing no freely adjustable parameters and valid for any alphabet size and any neighborhood range (including non-symmetrical neighborhoods). The map can be extended to an arbitrary number of dimensions and topologies and to arbitrary order in time. Specific CA maps for the famous Conway's Game of Life and Wolfram's 256 elementary CAs are given. An induction method for CAs, based in the universal map, allows mathematical expressions for the orbits of a wide variety of elementary CAs to be systematically derived. -- Highlights: ► A universal map is derived for all deterministic 1D cellular automata (CA). ► The map is generalized to 2D for Von Neumann, Moore and hexagonal neighborhoods. ► A map for all Wolfram's 256 elementary CAs is derived. ► A map for Conway's “Game of Life” is obtained.

  5. North America Synoptic Weather Maps

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Series of Synoptic Weather Maps. Maps contains a surface analysis comprised of plotted weather station observations, isobars indicating low and high-pressure...

  6. Associators in generalized octonionic maps

    International Nuclear Information System (INIS)

    Griffin, C.J.; Joshi, G.C.

    1994-01-01

    Generalizing previous work, it is shown that structural transitions are a general property of a large class of octonionic maps. They can thus be used as an indicator of non-associativity in an octonionic map. 7 refs., ills

  7. Mapping earthworm communities in Europe

    NARCIS (Netherlands)

    Rutgers, M.; Orgiazzi, A.; Gardi, C.; Römbke, J.; Jansch, S.; Keith, A.; Neilson, R.; Boag, B.; Schmidt, O.; Murchie, A.K.; Blackshaw, R.P.; Pérès, G.; Cluzeau, D.; Guernion, M.; Briones, M.J.I.; Rodeiro, J.; Pineiro, R.; Diaz Cosin, D.J.; Sousa, J.P.; Suhadolc, M.; Kos, I.; Krogh, P.H.; Faber, J.H.; Mulder, C.; Bogte, J.J.; Wijnen, van H.J.; Schouten, A.J.; Zwart, de D.

    2016-01-01

    Existing data sets on earthworm communities in Europe were collected, harmonized, collated, modelled and depicted on a soil biodiversity map. Digital Soil Mapping was applied using multiple regressions relating relatively low density earthworm community data to soil characteristics, land use,

  8. Map Usage in Virtual Environments

    National Research Council Canada - National Science Library

    Cevik, Helsin

    1998-01-01

    .... Instead, we can determine the parameters that affect virtual map representation and that help to construct a mental map, and then manipulate these parameters in order to increase the effectiveness...

  9. Mapping Deviant Democracy

    DEFF Research Database (Denmark)

    Seeberg, Michael

    2014-01-01

    A number of countries have emerged as stable (though minimalist) democracies despite low levels of modernization, lack of democratic neighbouring countries and other factors consistently related to democratic stability in the literature. The study of these deviant democracies is a promising new...... research field but it is afflicted by a notable problem, viz. the lack of a consensus as to which countries are actually instances of deviant democracy. The present article attempts to solve this problem by carrying out a comprehensive mapping of deviant democracies. First, I review the existing literature...... to provide an overview of the cases most often identified as deviant democracies. Second, I use a large-N analysis to systematically map deviant democracies. The analysis includes 159 countries covering the time period 1993–2008. The analysis points to 12 cases that merits further attention, viz...

  10. MAPS Appraisal Report Form

    CERN Multimedia

    HR Department

    2005-01-01

    As announced in Weekly Bulletin 48/2004, from now onwards, the paper MAPS appraisal report form has been replaced by an electronic form, which is available via EDH (on the EDH desktop under Other Tasks / HR & Training) No changes have been made to the contents of the form. Practical information will be available on the web page http://cern.ch/ais/projs/forms/maps/info.htm, and information meetings will be held on the following dates: 18 January 2005: MAIN AUDITORIUM (500-1-001) from 14:00 to 15:30. 20 January 2005: AB AUDITORIUM II (864-1-D02) from14:00 to 15:30. 24 January 2005: AT AUDITORIUM (30-7-018) from 10:00 to 11:30. Human Resources Department Tel. 73566

  11. Graphene mobility mapping

    DEFF Research Database (Denmark)

    Buron, Jonas Christian Due; Pizzocchero, Filippo; Jepsen, Peter Uhd

    2015-01-01

    Carrier mobility and chemical doping level are essential figures of merit for graphene, and large-scale characterization of these properties and their uniformity is a prerequisite for commercialization of graphene for electronics and electrodes. However, existing mapping techniques cannot directly...... assess these vital parameters in a non-destructive way. By deconvoluting carrier mobility and density from non-contact terahertz spectroscopic measurements of conductance in graphene samples with terahertz-transparent backgates, we are able to present maps of the spatial variation of both quantities over...... graphene indicates dominance by charged scatterers. Unexpectedly, significant variations in mobility rather than doping are the cause of large conductance inhomogeneities, highlighting the importance of statistical approaches when assessing large-area graphene transport properties....

  12. Mixed Map Labeling

    Directory of Open Access Journals (Sweden)

    Maarten Löffler

    2016-12-01

    Full Text Available Point feature map labeling is a geometric visualization problem, in which a set of input points must be labeled with a set of disjoint rectangles (the bounding boxes of the label texts. It is predominantly motivated by label placement in maps but it also has other visualization applications. Typically, labeling models either use internal labels, which must touch their feature point, or external (boundary labels, which are placed outside the input image and which are connected to their feature points by crossing-free leader lines. In this paper we study polynomial-time algorithms for maximizing the number of internal labels in a mixed labeling model that combines internal and external labels. The model requires that all leaders are parallel to a given orientation θ ∈ [0, 2π, the value of which influences the geometric properties and hence the running times of our algorithms.

  13. ASTROMETRIC REVERBERATION MAPPING

    International Nuclear Information System (INIS)

    Shen Yue

    2012-01-01

    Spatially extended emission regions of active galactic nuclei respond to continuum variations, if such emission regions are powered by energy reprocessing of the continuum. The response from different parts of the reverberating region arrives at different times lagging behind the continuum variation. The lags can be used to map the geometry and kinematics of the emission region (i.e., reverberation mapping, RM). If the extended emission region is not spherically symmetric in configuration and velocity space, reverberation may produce astrometric offsets in the emission region photocenter as a function of time delay and velocity, detectable with future μas to tens of μas astrometry. Such astrometric responses provide independent constraints on the geometric and kinematic structure of the extended emission region, complementary to traditional RM. In addition, astrometric RM is more sensitive to infer the inclination of a flattened geometry and the rotation angle of the extended emission region.

  14. Mapping Homophobia in Australia

    OpenAIRE

    Flood, Michael Gaston; Flood, Michael; Flood, C.; Hamilton, Clive

    2008-01-01

    One-third of the Australian population believe that 'homosexuality is immoral', and this belief is spread in distinct ways across the nation. Using data from a survey of nearly 25,000 Australians, we can 'map' homophobia in Australia. Homophobic attitudes are worst in country areas of Queensland and Tasmania. Men are far more likely than women to feel that homosexuality does not have moral legitimacy, and this gender gap in attitudes persists across age, socioeconomic, educational, and region...

  15. Intercreativity: Mapping Online Activism

    Science.gov (United States)

    Meikle, Graham

    How do activists use the Internet? This article maps a wide range of activist practice and research by applying and developing Tim Berners-Lee's concept of ‘intercreativity' (1999). It identifies four dimensions of Net activism: intercreative texts, tactics, strategies and networks. It develops these through examples of manifestations of Net activism around one cluster of issues: support campaigns for refugees and asylum seekers.

  16. MAP user's manual copyright

    International Nuclear Information System (INIS)

    Pillsbury, R.D. Jr.

    1991-12-01

    The program MITMAP represents a set of general purpose, two- dimensional, finite element programs for the calculation of magnetic fields. It consists of the program MAP and MAP2DJ. The two programs are used to solve different electromagnetic problems, but they have a common set of subrountines for pre- and postprocessing. Originally separate programs, they have been combined to make modification easier. The manuals, however, will remain separate. The program MAP is described in this manual. MAP is applicable to the class of problems with two-dimensional-planar or axisymmetric - geometries, in which the current density and the magnetic vector potential have only a single nonvanishing component. The single component is associated with the direction that is perpendicular to the plane of the problem and is invariant with respect to that direction. Maxwell's equations can be reduced to a solver diffusion equation in terms of the single, nonvanishing component of the magnetic vector potential for planar problems and to a single component of a vector potential for planar problems and to a single component of a vector diffusion equation for axisymmetric problems. The magnetic permeability appears in the governing equation. The permeability may be a function of the magnetic flux density. In addition, any electrically conducting material present will have eddy currents induced by a time varying magnetic field. These eddy currents must be included in the solution process. This manual provides a description of the structure of the input data and output for the program. There are several example problems presented that illustrate the major program features. Appendices are included that contain a derivation of the governing equations and the application of the finite element method to the solution of the equations

  17. Algebraic entropy for algebraic maps

    International Nuclear Information System (INIS)

    Hone, A N W; Ragnisco, Orlando; Zullo, Federico

    2016-01-01

    We propose an extension of the concept of algebraic entropy, as introduced by Bellon and Viallet for rational maps, to algebraic maps (or correspondences) of a certain kind. The corresponding entropy is an index of the complexity of the map. The definition inherits the basic properties from the definition of entropy for rational maps. We give an example with positive entropy, as well as two examples taken from the theory of Bäcklund transformations. (letter)

  18. Mind mapping in qualitative research.

    Science.gov (United States)

    Tattersall, Christopher; Powell, Julia; Stroud, James; Pringle, Jan

    We tested a theory that mind mapping could be used as a tool in qualitative research to transcribe and analyse an interview. We compared results derived from mind mapping with those from interpretive phenomenological analysis by examining patients' and carers' perceptions of a new nurse-led service. Mind mapping could be used to rapidly analyse simple qualitative audio-recorded interviews. More research is needed to establish the extent to which mind mapping can assist qualitative researchers.

  19. Fermion to boson mappings revisited

    International Nuclear Information System (INIS)

    Ginocchio, J.N.; Johnson, C.W.

    1996-01-01

    We briefly review various mappings of fermion pairs to bosons, including those based on mapping operators, such as Belyaev-Zelevinskii, and those on mapping states, such as Marumori; in particular we consider the work of Otsuka-Arima-Iachello, aimed at deriving the Interacting Boson Model. We then give a rigorous and unified description of state-mapping procedures which allows one to systematically go beyond Otsuka-Arima-Iachello and related approaches, along with several exact results. (orig.)

  20. Entropic Phase Maps in Discrete Quantum Gravity

    Directory of Open Access Journals (Sweden)

    Benjamin F. Dribus

    2017-06-01

    Full Text Available Path summation offers a flexible general approach to quantum theory, including quantum gravity. In the latter setting, summation is performed over a space of evolutionary pathways in a history configuration space. Discrete causal histories called acyclic directed sets offer certain advantages over similar models appearing in the literature, such as causal sets. Path summation defined in terms of these histories enables derivation of discrete Schrödinger-type equations describing quantum spacetime dynamics for any suitable choice of algebraic quantities associated with each evolutionary pathway. These quantities, called phases, collectively define a phase map from the space of evolutionary pathways to a target object, such as the unit circle S 1 ⊂ C , or an analogue such as S 3 or S 7 . This paper explores the problem of identifying suitable phase maps for discrete quantum gravity, focusing on a class of S 1 -valued maps defined in terms of “structural increments” of histories, called terminal states. Invariants such as state automorphism groups determine multiplicities of states, and induce families of natural entropy functions. A phase map defined in terms of such a function is called an entropic phase map. The associated dynamical law may be viewed as an abstract combination of Schrödinger’s equation and the second law of thermodynamics.

  1. The Spanish indoor radon mapping strategy

    International Nuclear Information System (INIS)

    Sainz-Fernandez, C.; Fernandez-Villar, A.; Fuente-Merino, I.; Gutierrez-Villanueva, J.L.; Casal-Ordas, S.; Quindos-Poncela, L.S.; Martin-Matarranz, J.L.; Garcia-Talavera, M.

    2014-01-01

    Indoor radon mapping still represents a valuable tool for drawing the picture of the exposure of general public due to radon and radon progeny inhalation in a residential context. The information provided by means of a map is useful not only as awareness and strategic element for authorities and policy-makers, but also as a scientific start-up point in the design of epidemiological and other specific studies on exposure to natural radiation. The requirements for a good mapping are related to harmonisation criteria coming from European recommendations, as well as to national/local characteristics and necessities. Around 12 000 indoor radon measurements have been made since the Spanish national radon programme began at the end of the 1980's. A significant proportion of them resulted from the last campaign performed from 2009 to 12. This campaign completed the first version of a map based on a grid 10 x 10 km 2 . In this paper, the authors present the main results of a new map together with the criteria adopted to improve the number of measurements and the statistical significance of them. (authors)

  2. Local adaptive tone mapping for video enhancement

    Science.gov (United States)

    Lachine, Vladimir; Dai, Min (.

    2015-03-01

    As new technologies like High Dynamic Range cameras, AMOLED and high resolution displays emerge on consumer electronics market, it becomes very important to deliver the best picture quality for mobile devices. Tone Mapping (TM) is a popular technique to enhance visual quality. However, the traditional implementation of Tone Mapping procedure is limited by pixel's value to value mapping, and the performance is restricted in terms of local sharpness and colorfulness. To overcome the drawbacks of traditional TM, we propose a spatial-frequency based framework in this paper. In the proposed solution, intensity component of an input video/image signal is split on low pass filtered (LPF) and high pass filtered (HPF) bands. Tone Mapping (TM) function is applied to LPF band to improve the global contrast/brightness, and HPF band is added back afterwards to keep the local contrast. The HPF band may be adjusted by a coring function to avoid noise boosting and signal overshooting. Colorfulness of an original image may be preserved or enhanced by chroma components correction by means of saturation function. Localized content adaptation is further improved by dividing an image to a set of non-overlapped regions and modifying each region individually. The suggested framework allows users to implement a wide range of tone mapping applications with perceptional local sharpness and colorfulness preserved or enhanced. Corresponding hardware circuit may be integrated in camera, video or display pipeline with minimal hardware budget

  3. Classifying the Diversity of Bus Mapping Systems

    Science.gov (United States)

    Said, Mohd Shahmy Mohd; Forrest, David

    2018-05-01

    This study represents the first stage of an investigation into understanding the nature of different approaches to mapping bus routes and bus network, and how they may best be applied in different public transport situations. In many cities, bus services represent an important facet of easing traffic congestion and reducing pollution. However, with the entrenched car culture in many countries, persuading people to change their mode of transport is a major challenge. To promote this modal shift, people need to know what services are available and where (and when) they go. Bus service maps provide an invaluable element of providing suitable public transport information, but are often overlooked by transport planners, and are under-researched by cartographers. The method here consists of the creation of a map evaluation form and performing assessment of published bus networks maps. The analyses were completed by a combination of quantitative and qualitative data analysis of various aspects of cartographic design and classification. This paper focuses on the resulting classification, which is illustrated by a series of examples. This classification will facilitate more in depth investigations into the details of cartographic design for such maps and help direct areas for user evaluation.

  4. Digital mapping in extreme and remote environments

    Science.gov (United States)

    Andersson, Joel; Bauer, Tobias; Sarlus, Zimer; Zainy, Maher; Brethes, Anais

    2017-04-01

    During the last few years, Luleå University of Technology has performed a series of research projects in remote areas with extreme climatic conditions using digital mapping technologies. The majority of past and ongoing research projects focus on the arctic regions of the Fennoscandian Shield and Greenland but also on the Zagros fold-and-thrust belt in northern Iraq. Currently, we use the Midland Valley application FieldMove on iPad mini devices with ruggedized casings. As all projects have a strong focus on geological field work, harsh climatic conditions are a challenge not only for the geologists but also for the digital mapping hardware. In the arctic regions especially cold temperatures affect battery lifetime and performance of the screens. But also high temperatures are restricting digital mapping. From experience, a typical temperature range where digital mapping, using iPad tablets, is possible lies between -20 and +40 degrees. Furthermore, the remote character of field areas complicates access but also availability of electricity. By a combination of robust solar chargers and ruggedized batteries we are able to work entirely autarkical. Additionally, we are currently installing a drone system that allows us to map outcrops normally inaccessible because of safety reasons or time deficiency. The produced data will subsequently be taken into our Virtual Reality studio for interpretation and processing. There we will be able to work also with high resolution DEM data from Lidar scanning allowing us to interpret structural features such as post-glacial faults in areas that are otherwise only accessible by helicopter. By combining digital field mapping with drone technique and a Virtual Reality studio we are able to work in hardly accessible areas, improve safety during field work and increase efficiency substantially.

  5. Mapping in inertial frames

    International Nuclear Information System (INIS)

    Arunasalam, V.

    1989-05-01

    World space mapping in inertial frames is used to examine the Lorentz covariance of symmetry operations. It is found that the Galilean invariant concepts of simultaneity (S), parity (P), and time reversal symmetry (T) are not Lorentz covariant concepts for inertial observers. That is, just as the concept of simultaneity has no significance independent of the Lorentz inertial frame, likewise so are the concepts of parity and time reversal. However, the world parity (W) [i.e., the space-time reversal symmetry (P-T)] is a truly Lorentz covariant concept. Indeed, it is shown that only those mapping matrices M that commute with the Lorentz transformation matrix L (i.e., [M,L] = 0) are the ones that correspond to manifestly Lorentz covariant operations. This result is in accordance with the spirit of the world space Mach's principle. Since the Lorentz transformation is an orthogonal transformation while the Galilean transformation is not an orthogonal transformation, the formal relativistic space-time mapping theory used here does not have a corresponding non-relativistic counterpart. 12 refs

  6. Lectures on quasiconformal mappings

    CERN Document Server

    Ahlfors, Lars V

    2006-01-01

    Lars Ahlfors's Lectures on Quasiconformal Mappings, based on a course he gave at Harvard University in the spring term of 1964, was first published in 1966 and was soon recognized as the classic it was shortly destined to become. These lectures develop the theory of quasiconformal mappings from scratch, give a self-contained treatment of the Beltrami equation, and cover the basic properties of Teichm�ller spaces, including the Bers embedding and the Teichm�ller curve. It is remarkable how Ahlfors goes straight to the heart of the matter, presenting major results with a minimum set of prerequisites. Many graduate students and other mathematicians have learned the foundations of the theories of quasiconformal mappings and Teichm�ller spaces from these lecture notes. This edition includes three new chapters. The first, written by Earle and Kra, describes further developments in the theory of Teichm�ller spaces and provides many references to the vast literature on Teichm�ller spaces and quasiconformal ...

  7. Using Playground Maps for Movement

    Science.gov (United States)

    Colvin, A. Vonnie

    2016-01-01

    Many schools now decorate their outside hard surface areas with maps. These maps provide color and excitement to a playground and are a terrific teaching tool for geography. But these maps can easily be integrated into physical education as well to promote both physical activity as well as knowledge of geography. The purpose of this article is to…

  8. Drawing subway maps : a survey

    NARCIS (Netherlands)

    Wolff, A.

    2007-01-01

    This paper deals with automating the drawing of subway maps. There are two features of schematic subway maps that make them different from drawings of other networks such as flow charts or organigrams. First, most schematic subway maps use not only horizontal and vertical lines, but also diagonals.

  9. Genetic algorithms for map labeling

    NARCIS (Netherlands)

    Dijk, Steven Ferdinand van

    2001-01-01

    Map labeling is the cartographic problem of placing the names of features (for example cities or rivers) on the map. A good labeling has no intersections between labels. Even basic versions of the problem are NP-hard. In addition, realistic map-labeling problems deal with many cartographic

  10. Try This: Collaborative Mind Mapping

    Science.gov (United States)

    Mendelson, Melissa

    2016-01-01

    In this "Try This" article, students learn about collaborative mind mapping. A mind map is a type of graphic organizer that allows for short ideas to be written and linked to related ideas on a "map." A central idea is placed in the middle of the paper with related ideas connected to the central idea as well as to other ideas.…

  11. Adaptive proxy map server for efficient vector spatial data rendering

    Science.gov (United States)

    Sayar, Ahmet

    2013-01-01

    The rapid transmission of vector map data over the Internet is becoming a bottleneck of spatial data delivery and visualization in web-based environment because of increasing data amount and limited network bandwidth. In order to improve both the transmission and rendering performances of vector spatial data over the Internet, we propose a proxy map server enabling parallel vector data fetching as well as caching to improve the performance of web-based map servers in a dynamic environment. Proxy map server is placed seamlessly anywhere between the client and the final services, intercepting users' requests. It employs an efficient parallelization technique based on spatial proximity and data density in case distributed replica exists for the same spatial data. The effectiveness of the proposed technique is proved at the end of the article by the application of creating map images enriched with earthquake seismic data records.

  12. A Novel Audio Cryptosystem Using Chaotic Maps and DNA Encoding

    Directory of Open Access Journals (Sweden)

    S. J. Sheela

    2017-01-01

    Full Text Available Chaotic maps have good potential in security applications due to their inherent characteristics relevant to cryptography. This paper introduces a new audio cryptosystem based on chaotic maps, hybrid chaotic shift transform (HCST, and deoxyribonucleic acid (DNA encoding rules. The scheme uses chaotic maps such as two-dimensional modified Henon map (2D-MHM and standard map. The 2D-MHM which has sophisticated chaotic behavior for an extensive range of control parameters is used to perform HCST. DNA encoding technology is used as an auxiliary tool which enhances the security of the cryptosystem. The performance of the algorithm is evaluated for various speech signals using different encryption/decryption quality metrics. The simulation and comparison results show that the algorithm can achieve good encryption results and is able to resist several cryptographic attacks. The various types of analysis revealed that the algorithm is suitable for narrow band radio communication and real-time speech encryption applications.

  13. Habitat Mapping Cruise - Hudson Canyon (HB0904, EK60)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Objectives are to: 1) perform multibeam mapping of transitional and deepwater habitats in Hudson Canyon (off New Jersey) with the National Institute of Undersea...

  14. High-throughput SNP genotyping in Cucurbita pepo for map construction and quantitative trait loci mapping.

    Science.gov (United States)

    Esteras, Cristina; Gómez, Pedro; Monforte, Antonio J; Blanca, José; Vicente-Dólera, Nelly; Roig, Cristina; Nuez, Fernando; Picó, Belén

    2012-02-22

    Cucurbita pepo is a member of the Cucurbitaceae family, the second- most important horticultural family in terms of economic importance after Solanaceae. The "summer squash" types, including Zucchini and Scallop, rank among the highest-valued vegetables worldwide. There are few genomic tools available for this species.The first Cucurbita transcriptome, along with a large collection of Single Nucleotide Polymorphisms (SNP), was recently generated using massive sequencing. A set of 384 SNP was selected to generate an Illumina GoldenGate assay in order to construct the first SNP-based genetic map of Cucurbita and map quantitative trait loci (QTL). We herein present the construction of the first SNP-based genetic map of Cucurbita pepo using a population derived from the cross of two varieties with contrasting phenotypes, representing the main cultivar groups of the species' two subspecies: Zucchini (subsp. pepo) × Scallop (subsp. ovifera). The mapping population was genotyped with 384 SNP, a set of selected EST-SNP identified in silico after massive sequencing of the transcriptomes of both parents, using the Illumina GoldenGate platform. The global success rate of the assay was higher than 85%. In total, 304 SNP were mapped, along with 11 SSR from a previous map, giving a map density of 5.56 cM/marker. This map was used to infer syntenic relationships between C. pepo and cucumber and to successfully map QTL that control plant, flowering and fruit traits that are of benefit to squash breeding. The QTL effects were validated in backcross populations. Our results show that massive sequencing in different genotypes is an excellent tool for SNP discovery, and that the Illumina GoldenGate platform can be successfully applied to constructing genetic maps and performing QTL analysis in Cucurbita. This is the first SNP-based genetic map in the Cucurbita genus and is an invaluable new tool for biological research, especially considering that most of these markers are located in

  15. Single-edition quadrangle maps

    Science.gov (United States)

    ,

    1998-01-01

    In August 1993, the U.S. Geological Survey's (USGS) National Mapping Division and the U.S. Department of Agriculture's Forest Service signed an Interagency Agreement to begin a single-edition joint mapping program. This agreement established the coordination for producing and maintaining single-edition primary series topographic maps for quadrangles containing National Forest System lands. The joint mapping program saves money by eliminating duplication of effort by the agencies and results in a more frequent revision cycle for quadrangles containing national forests. Maps are revised on the basis of jointly developed standards and contain normal features mapped by the USGS, as well as additional features required for efficient management of National Forest System lands. Single-edition maps look slightly different but meet the content, accuracy, and quality criteria of other USGS products. The Forest Service is responsible for the land management of more than 191 million acres of land throughout the continental United States, Alaska, and Puerto Rico, including 155 national forests and 20 national grasslands. These areas make up the National Forest System lands and comprise more than 10,600 of the 56,000 primary series 7.5-minute quadrangle maps (15-minute in Alaska) covering the United States. The Forest Service has assumed responsibility for maintaining these maps, and the USGS remains responsible for printing and distributing them. Before the agreement, both agencies published similar maps of the same areas. The maps were used for different purposes, but had comparable types of features that were revised at different times. Now, the two products have been combined into one so that the revision cycle is stabilized and only one agency revises the maps, thus increasing the number of current maps available for National Forest System lands. This agreement has improved service to the public by requiring that the agencies share the same maps and that the maps meet a

  16. M3: Matrix Multiplication on MapReduce

    DEFF Research Database (Denmark)

    Silvestri, Francesco; Ceccarello, Matteo

    2015-01-01

    M3 is an Hadoop library for performing dense and sparse matrix multiplication in MapReduce. The library is based on multi-round algorithms exploiting the 3D decomposition of the problem.......M3 is an Hadoop library for performing dense and sparse matrix multiplication in MapReduce. The library is based on multi-round algorithms exploiting the 3D decomposition of the problem....

  17. Timed bisimulation and open maps

    DEFF Research Database (Denmark)

    Hune, Thomas; Nielsen, Mogens

    1998-01-01

    of timed bisimulation. Thus the abstract results from the theory of open maps apply, e.g. the existence of canonical models and characteristic logics. Here, we provide an alternative proof of decidability of bisimulation for finite timed transition systems in terms of open maps, and illustrate the use......Open maps have been used for defining bisimulations for a range of models, but none of these have modelled real-time. We define a category of timed transition systems, and use the general framework of open maps to obtain a notion of bisimulation. We show this to be equivalent to the standard notion...... of open maps in presenting bisimulations....

  18. A guide of patent map

    International Nuclear Information System (INIS)

    1999-12-01

    This book introduces application and characteristic of patent information, types of patent information data and research of patent information, arrangement of patent information and patent map, analysis of patent information, necessity, writing period arrangement way of patent map, cases of patent map on selection of task of research and development, system of research and development and application, examples of PM such as MAP by year, application, technique, Inventor, and claim point map and computerization like data arrangement of PM patent, collection of analysis range and item analysis of patent, cases and written reports on patent analysis.

  19. Proportional Symbol Mapping in R

    Directory of Open Access Journals (Sweden)

    Susumu Tanimura

    2006-01-01

    Full Text Available Visualization of spatial data on a map aids not only in data exploration but also in communication to impart spatial conception or ideas to others. Although recent carto-graphic functions in R are rapidly becoming richer, proportional symbol mapping, which is one of the common mapping approaches, has not been packaged thus far. Based on the theories of proportional symbol mapping developed in cartography, the authors developed some functions for proportional symbol mapping using R, including mathematical and perceptual scaling. An example of these functions demonstrated the new expressive power and options available in R, particularly for the visualization of conceptual point data.

  20. T 2 mapping of cerebrospinal fluid

    DEFF Research Database (Denmark)

    Spijkerman, Jolanda M; Petersen, Esben T; Hendrikse, Jeroen

    2018-01-01

    the performance of this method at 7 T and evaluated the influence of partial volume and B 1 and B 0 inhomogeneity. MATERIALS AND METHODS: T 2-preparation-based CSF T 2-mapping was performed in seven healthy volunteers at 7 and 3 T, and was compared with a single echo spin-echo sequence with various echo times......OBJECT: Cerebrospinal fluid (CSF) T 2 mapping can potentially be used to investigate CSF composition. A previously proposed CSF T 2-mapping method reported a T 2 difference between peripheral and ventricular CSF, and suggested that this reflected different CSF compositions. We studied....... The influence of partial volume was assessed by our analyzing the longest echo times only. B 1 and B 0 maps were acquired. B 1 and B 0 dependency of the sequences was tested with a phantom. RESULTS: T 2,CSF was shorter at 7 T compared with 3 T. At 3 T, but not at 7 T, peripheral T 2,CSF was significantly...

  1. Inferring the most probable maps of underground utilities using Bayesian mapping model

    Science.gov (United States)

    Bilal, Muhammad; Khan, Wasiq; Muggleton, Jennifer; Rustighi, Emiliano; Jenks, Hugo; Pennock, Steve R.; Atkins, Phil R.; Cohn, Anthony

    2018-03-01

    Mapping the Underworld (MTU), a major initiative in the UK, is focused on addressing social, environmental and economic consequences raised from the inability to locate buried underground utilities (such as pipes and cables) by developing a multi-sensor mobile device. The aim of MTU device is to locate different types of buried assets in real time with the use of automated data processing techniques and statutory records. The statutory records, even though typically being inaccurate and incomplete, provide useful prior information on what is buried under the ground and where. However, the integration of information from multiple sensors (raw data) with these qualitative maps and their visualization is challenging and requires the implementation of robust machine learning/data fusion approaches. An approach for automated creation of revised maps was developed as a Bayesian Mapping model in this paper by integrating the knowledge extracted from sensors raw data and available statutory records. The combination of statutory records with the hypotheses from sensors was for initial estimation of what might be found underground and roughly where. The maps were (re)constructed using automated image segmentation techniques for hypotheses extraction and Bayesian classification techniques for segment-manhole connections. The model consisting of image segmentation algorithm and various Bayesian classification techniques (segment recognition and expectation maximization (EM) algorithm) provided robust performance on various simulated as well as real sites in terms of predicting linear/non-linear segments and constructing refined 2D/3D maps.

  2. Derivation of the dipole map

    International Nuclear Information System (INIS)

    Ali, Halima; Punjabi, Alkesh; Boozer, Allen

    2004-01-01

    In our method of maps [Punjabi et al., Phy. Rev. Lett. 69, 3322 (1992), and Punjabi et al., J. Plasma Phys. 52, 91 (1994)], symplectic maps are used to calculate the trajectories of magnetic field lines in divertor tokamaks. Effects of the magnetic perturbations are calculated using the low MN map [Ali et al., Phys. Plasmas 11, 1908 (2004)] and the dipole map [Punjabi et al., Phys. Plasmas 10, 3992 (2003)]. The dipole map is used to calculate the effects of externally located current carrying coils on the trajectories of the field lines, the stochastic layer, the magnetic footprint, and the heat load distribution on the collector plates in divertor tokamaks [Punjabi et al., Phys. Plasmas 10, 3992 (2003)]. Symplectic maps are general, efficient, and preserve and respect the Hamiltonian nature of the dynamics. In this brief communication, a rigorous mathematical derivation of the dipole map is given

  3. Looking for an old map

    Science.gov (United States)

    ,

    1996-01-01

    Many people want maps that show an area of the United States as it existed many years ago. These are called historical maps, and there are two types. The most common type consists of special maps prepared by commercial firms to show such historical features as battle-fields, military routes, or the paths taken by famous travelers. Typically, these maps are for sale to tourists at the sites of historical events. The other type is the truly old map--one compiled by a surveyor or cartographer many years ago. Lewis and Clark, for example, made maps of their journeys into the Northwest Territories in 1803-6, and originals of some of these maps still exist.

  4. Conceptual maps as evaluation strategy

    Directory of Open Access Journals (Sweden)

    Dionísio Borsato

    2007-03-01

    Full Text Available The following work shows the conceptual map as an evaluation tool. In this study, an opening text was used as a previous organizer, with a theme related to the students’ daily lives. The developed activity consisted in elaborating conceptual maps before and after the experimental works. The evaluation was applied to 21 students of the 1st grade and 22 of the 3rd grade of High School. The elaborated maps were scored according to hierarchy, propositions, linking words, cross linking and examples. The classification of the maps elaborated before and after the experimental activity, was obtained having as a parameter, a referential conceptual map. In this classification many differences were observed between the first and second maps of both grades and among the groups. The elaboration of conceptual maps showed great potential as evaluation resources.

  5. Online Exhibits & Concept Maps

    Science.gov (United States)

    Douma, M.

    2009-12-01

    Presenting the complexity of geosciences to the public via the Internet poses a number of challenges. For example, utilizing various - and sometimes redundant - Web 2.0 tools can quickly devour limited time. Do you tweet? Do you write press releases? Do you create an exhibit or concept map? The presentation will provide participants with a context for utilizing Web 2.0 tools by briefly highlighting methods of online scientific communication across several dimensions. It will address issues of: * breadth and depth (e.g. from narrow topics to well-rounded views), * presentation methods (e.g. from text to multimedia, from momentary to enduring), * sources and audiences (e.g. for experts or for the public, content developed by producers to that developed by users), * content display (e.g. from linear to non-linear, from instructive to entertaining), * barriers to entry (e.g. from an incumbent advantage to neophyte accessible, from amateur to professional), * cost and reach (e.g. from cheap to expensive), and * impact (e.g. the amount learned, from anonymity to brand awareness). Against this backdrop, the presentation will provide an overview of two methods of online information dissemination, exhibits and concept maps, using the WebExhibits online museum (www.webexhibits.org) and SpicyNodes information visualization tool (www.spicynodes.org) as examples, with tips on how geoscientists can use either to communicate their science. Richly interactive online exhibits can serve to engage a large audience, appeal to visitors with multiple learning styles, prompt exploration and discovery, and present a topic’s breadth and depth. WebExhibits, which was among the first online museums, delivers interactive information, virtual experiments, and hands-on activities to the public. While large, multidisciplinary exhibits on topics like “Color Vision and Art” or “Calendars Through the Ages” require teams of scholars, user interface experts, professional writers and editors

  6. Probability mapping of contaminants

    Energy Technology Data Exchange (ETDEWEB)

    Rautman, C.A.; Kaplan, P.G. [Sandia National Labs., Albuquerque, NM (United States); McGraw, M.A. [Univ. of California, Berkeley, CA (United States); Istok, J.D. [Oregon State Univ., Corvallis, OR (United States); Sigda, J.M. [New Mexico Inst. of Mining and Technology, Socorro, NM (United States)

    1994-04-01

    Exhaustive characterization of a contaminated site is a physical and practical impossibility. Descriptions of the nature, extent, and level of contamination, as well as decisions regarding proposed remediation activities, must be made in a state of uncertainty based upon limited physical sampling. The probability mapping approach illustrated in this paper appears to offer site operators a reasonable, quantitative methodology for many environmental remediation decisions and allows evaluation of the risk associated with those decisions. For example, output from this approach can be used in quantitative, cost-based decision models for evaluating possible site characterization and/or remediation plans, resulting in selection of the risk-adjusted, least-cost alternative. The methodology is completely general, and the techniques are applicable to a wide variety of environmental restoration projects. The probability-mapping approach is illustrated by application to a contaminated site at the former DOE Feed Materials Production Center near Fernald, Ohio. Soil geochemical data, collected as part of the Uranium-in-Soils Integrated Demonstration Project, have been used to construct a number of geostatistical simulations of potential contamination for parcels approximately the size of a selective remediation unit (the 3-m width of a bulldozer blade). Each such simulation accurately reflects the actual measured sample values, and reproduces the univariate statistics and spatial character of the extant data. Post-processing of a large number of these equally likely statistically similar images produces maps directly showing the probability of exceeding specified levels of contamination (potential clean-up or personnel-hazard thresholds).

  7. Probability mapping of contaminants

    International Nuclear Information System (INIS)

    Rautman, C.A.; Kaplan, P.G.; McGraw, M.A.; Istok, J.D.; Sigda, J.M.

    1994-01-01

    Exhaustive characterization of a contaminated site is a physical and practical impossibility. Descriptions of the nature, extent, and level of contamination, as well as decisions regarding proposed remediation activities, must be made in a state of uncertainty based upon limited physical sampling. The probability mapping approach illustrated in this paper appears to offer site operators a reasonable, quantitative methodology for many environmental remediation decisions and allows evaluation of the risk associated with those decisions. For example, output from this approach can be used in quantitative, cost-based decision models for evaluating possible site characterization and/or remediation plans, resulting in selection of the risk-adjusted, least-cost alternative. The methodology is completely general, and the techniques are applicable to a wide variety of environmental restoration projects. The probability-mapping approach is illustrated by application to a contaminated site at the former DOE Feed Materials Production Center near Fernald, Ohio. Soil geochemical data, collected as part of the Uranium-in-Soils Integrated Demonstration Project, have been used to construct a number of geostatistical simulations of potential contamination for parcels approximately the size of a selective remediation unit (the 3-m width of a bulldozer blade). Each such simulation accurately reflects the actual measured sample values, and reproduces the univariate statistics and spatial character of the extant data. Post-processing of a large number of these equally likely statistically similar images produces maps directly showing the probability of exceeding specified levels of contamination (potential clean-up or personnel-hazard thresholds)

  8. Mapping the gendered city

    DEFF Research Database (Denmark)

    Almahmood, Mohammed Abdulrahman M; Scharnhorst, Eric; Carstensen, Trine Agervig

    2017-01-01

    opportunities for gender interaction. However, streets are socially conceived as men’s walkscapes, which limits women’s presence, especially at certain times of the day. This paper reveals how walking experience, tempo-rhythm, sense of place and range of walkscapes are not only determined by ‘universal’ spatial...... Peninsula, where socio-cultural values and restrictions regulate men and women’s use and access to public spaces. The methodology used is a combination of movement tracking data using GPS technology and map-based workshops where participants can reflect on their walking behaviour and spatial preferences...

  9. Bisimulation and open maps

    DEFF Research Database (Denmark)

    Joyal, André; Nielsen, Mogens; Winskel, Glynn

    1993-01-01

    Petri nets), and labeled event structures are considered. On transition systems, the abstract definition readily specialises to Milner's (1989) strong bisimulation. On event structures, it explains and leads to a revision of the history-preserving bisimulation of Rabinovitch and Traktenbrot (1988......), and Goltz and van Glabeek (1989). A tie-up with open maps in a (pre)topos brings to light a promising new model, presheaves on categories of pomsets, into which the usual category of labeled event structures embeds fully and faithfully. As an indication of its promise, this new presheaf model has refinement...

  10. Journal of Maps

    Directory of Open Access Journals (Sweden)

    Nedjeljko Frančula

    2009-12-01

    Full Text Available Journal of Maps (JoM (http://www.journalofmaps.com počeo je izlaziti 2005. godine isključivo kao elektronički časopis. Izdavač je School of Earth Sciences and Geography, Kingston University, UK. Budući da ne izlazi u tiskanom izdanju, časopis nema uobičajene sveske. Svescima se, ipak, mogu smatrati članci srodne tematike koji se objavljuju tri puta godišnje – u travnju, kolovozu i prosincu.

  11. Corrosion mapping in pipelines

    International Nuclear Information System (INIS)

    Zscherpel, U.; Alekseychuk, O.; Bellon, C.; Ewert, U.; Rost, P.; Schmid, M.

    2002-01-01

    In a joint research project, BASF AG and BAM analyzed the state of the art of tangential radiography of pipes and developed more efficient methods of evaluation. Various PC applications were developed and tested: 1. A program for routine evaluation of digital radiographic images. 2. 3D simulation of the tangential projection of pipes for common radiation sources and various different detectors. 3. Preliminary work on combined evaluation of digital projections and wall thickness changes in radiation direction resulted in a new manner of image display, i.e. the so-called 'corrosion mapping', in which the wall thickness is displayed as a 2D picture above the pipe surface [de

  12. Mapping Wind Energy Controversies

    DEFF Research Database (Denmark)

    Munk, Anders Kristian

    As part the Wind2050 project funded by the Danish Council for Strategic Research we have mapped controversies on wind energy as they unfold online. Specifically we have collected two purpose built datasets, a web corpus containing information from 758 wind energy websites in 6 different countries......, and a smaller social media corpus containing information from 14 Danish wind energy pages on Facebook. These datasets have been analyzed to answer questions like: How do wind proponents and opponents organize online? Who are the central actors? And what are their matters of concern? The purpose of this report...

  13. Mapping of renewable energies

    International Nuclear Information System (INIS)

    Boulanger, V.

    2013-01-01

    Germany is the champion of green energy in Europe: the contribution of renewable energies to electricity generation reached about 20% in 2011. This article describes the situation of renewable energies in Germany in 2011 with the help of 2 maps, the first one gives the installed electrical generation capacity for each region and for each renewable energy source (wind power, hydro-electricity, biomass, photovoltaic energy and biogas) and the second one details the total number of jobs (direct and indirect) for each renewable energy source and for each region. In 2011 about 372000 people worked in the renewable energy sector in Germany. (A.C.)

  14. YouGenMap: a web platform for dynamic multi-comparative mapping and visualization of genetic maps

    Science.gov (United States)

    Keith Batesole; Kokulapalan Wimalanathan; Lin Liu; Fan Zhang; Craig S. Echt; Chun Liang

    2014-01-01

    Comparative genetic maps are used in examination of genome organization, detection of conserved gene order, and exploration of marker order variations. YouGenMap is an open-source web tool that offers dynamic comparative mapping capability of users' own genetic mapping between 2 or more map sets. Users' genetic map data and optional gene annotations are...

  15. REST-MapReduce: An Integrated Interface but Differentiated Service

    Directory of Open Access Journals (Sweden)

    Jong-Hyuk Park

    2014-01-01

    Full Text Available With the fast deployment of cloud computing, MapReduce architectures are becoming the major technologies for mobile cloud computing. The concept of MapReduce was first introduced as a novel programming model and implementation for a large set of computing devices. In this research, we propose a novel concept of REST-MapReduce, enabling users to use only the REST interface without using the MapReduce architecture. This approach provides a higher level of abstraction by integration of the two types of access interface, REST API and MapReduce. The motivation of this research stems from the slower response time for accessing simple RDBMS on Hadoop than direct access to RDMBS. This is because there is overhead to job scheduling, initiating, starting, tracking, and management during MapReduce-based parallel execution. Therefore, we provide a good performance for REST Open API service and for MapReduce, respectively. This is very useful for constructing REST Open API services on Hadoop hosting services, for example, Amazon AWS (Macdonald, 2005 or IBM Smart Cloud. For evaluating performance of our REST-MapReduce framework, we conducted experiments with Jersey REST web server and Hadoop. Experimental result shows that our approach outperforms conventional approaches.

  16. Online maps with APIs and webservices

    CERN Document Server

    Peterson, Michael P

    2014-01-01

    With the Internet now the primary method of accessing maps, this volume examines developments in the world of online map delivery, focusing in particular on application programmer interfaces such as the Google Maps API, and their utility in thematic mapping.

  17. Validation and application of Acoustic Mapping Velocimetry

    Science.gov (United States)

    Baranya, Sandor; Muste, Marian

    2016-04-01

    The goal of this paper is to introduce a novel methodology to estimate bedload transport in rivers based on an improved bedform tracking procedure. The measurement technique combines components and processing protocols from two contemporary nonintrusive instruments: acoustic and image-based. The bedform mapping is conducted with acoustic surveys while the estimation of the velocity of the bedforms is obtained with processing techniques pertaining to image-based velocimetry. The technique is therefore called Acoustic Mapping Velocimetry (AMV). The implementation of this technique produces a whole-field velocity map associated with the multi-directional bedform movement. Based on the calculated two-dimensional bedform migration velocity field, the bedload transport estimation is done using the Exner equation. A proof-of-concept experiment was performed to validate the AMV based bedload estimation in a laboratory flume at IIHR-Hydroscience & Engineering (IIHR). The bedform migration was analysed at three different flow discharges. Repeated bed geometry mapping, using a multiple transducer array (MTA), provided acoustic maps, which were post-processed with a particle image velocimetry (PIV) method. Bedload transport rates were calculated along longitudinal sections using the streamwise components of the bedform velocity vectors and the measured bedform heights. The bulk transport rates were compared with the results from concurrent direct physical samplings and acceptable agreement was found. As a first field implementation of the AMV an attempt was made to estimate bedload transport for a section of the Ohio river in the United States, where bed geometry maps, resulted by repeated multibeam echo sounder (MBES) surveys, served as input data. Cross-sectional distributions of bedload transport rates from the AMV based method were compared with the ones obtained from another non-intrusive technique (due to the lack of direct samplings), ISSDOTv2, developed by the US Army

  18. BAC-HAPPY mapping (BAP mapping: a new and efficient protocol for physical mapping.

    Directory of Open Access Journals (Sweden)

    Giang T H Vu

    2010-02-01

    Full Text Available Physical and linkage mapping underpin efforts to sequence and characterize the genomes of eukaryotic organisms by providing a skeleton framework for whole genome assembly. Hitherto, linkage and physical "contig" maps were generated independently prior to merging. Here, we develop a new and easy method, BAC HAPPY MAPPING (BAP mapping, that utilizes BAC library pools as a HAPPY mapping panel together with an Mbp-sized DNA panel to integrate the linkage and physical mapping efforts into one pipeline. Using Arabidopsis thaliana as an exemplar, a set of 40 Sequence Tagged Site (STS markers spanning approximately 10% of chromosome 4 were simultaneously assembled onto a BAP map compiled using both a series of BAC pools each comprising 0.7x genome coverage and dilute (0.7x genome samples of sheared genomic DNA. The resultant BAP map overcomes the need for polymorphic loci to separate genetic loci by recombination and allows physical mapping in segments of suppressed recombination that are difficult to analyze using traditional mapping techniques. Even virtual "BAC-HAPPY-mapping" to convert BAC landing data into BAC linkage contigs is possible.

  19. RESEARCH NOTE Molecular genetic analysis of consanguineous ...

    Indian Academy of Sciences (India)

    Navya

    Molecular genetic analysis of consanguineous families with primary microcephaly ... Translational Research Institute, Academic Health System, Hamad Medical ..... bridging the gap between homozygosity mapping and deep sequencing.

  20. Mapping the Field

    DEFF Research Database (Denmark)

    Goerres, Achim; Vanhuysse, Pieter

    2012-01-01

    Whereas the call for a political science based study of older people and ageing is not new (Cutler 1977; Heclo 1988), relatively little unified progress has been made so far. This chapter maps the field of generational politics and introduces our edited volume "Ageing Populations in Post-Industri......Whereas the call for a political science based study of older people and ageing is not new (Cutler 1977; Heclo 1988), relatively little unified progress has been made so far. This chapter maps the field of generational politics and introduces our edited volume "Ageing Populations in Post...... boxes by asking a number of central questions. How does population aging change political support for redistribution towards different age groups in society, including not just elderly people but also families with children? How, and when, do established parties in aging democracies implement policies......? The answers provided in this volume promise to be of major interest to scholars in fields such as political economy, political sociology, social policy, comparative politics, demography, and gerontology....

  1. Quantitive DNA Fiber Mapping

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Chun-Mei; Wang, Mei; Greulich-Bode, Karin M.; Weier, Jingly F.; Weier, Heinz-Ulli G.

    2008-01-28

    Several hybridization-based methods used to delineate single copy or repeated DNA sequences in larger genomic intervals take advantage of the increased resolution and sensitivity of free chromatin, i.e., chromatin released from interphase cell nuclei. Quantitative DNA fiber mapping (QDFM) differs from the majority of these methods in that it applies FISH to purified, clonal DNA molecules which have been bound with at least one end to a solid substrate. The DNA molecules are then stretched by the action of a receding meniscus at the water-air interface resulting in DNA molecules stretched homogeneously to about 2.3 kb/{micro}m. When non-isotopically, multicolor-labeled probes are hybridized to these stretched DNA fibers, their respective binding sites are visualized in the fluorescence microscope, their relative distance can be measured and converted into kilobase pairs (kb). The QDFM technique has found useful applications ranging from the detection and delineation of deletions or overlap between linked clones to the construction of high-resolution physical maps to studies of stalled DNA replication and transcription.

  2. ANNUAL INTERVIEWS (MAPS)

    CERN Multimedia

    Human Resources Division

    2002-01-01

    The calendar for the 2002/2003 annual interview programme is confirmed as normally from 15 November 2002 to 15 February 2002 as foreseen in Administrative Circular N° 26 (rev. 2). However, where it is preferred to be as close as possible to 12 months since the last interview, supervisors and staff concerned may agree to the interview taking place up to 15 March 2003. This may also be necessary due to the roles of different supervisors resulting from the particular situations of divisional re-restructurings and detachments this year. The report form template is as last year available on the HR Division Website. A banner on the internal homepage leads directly to the page with the form. In collaboration with AS Division, the MAPS form including the personal data for the first page can be generated via the Human Resources Toolkit (HRT) application. For this exercise each staff member can now generate his/her own MAPS form. Information about how to do this is available here. Human Resources Division Tel. ...

  3. Statistical methods in physical mapping

    International Nuclear Information System (INIS)

    Nelson, D.O.

    1995-05-01

    One of the great success stories of modern molecular genetics has been the ability of biologists to isolate and characterize the genes responsible for serious inherited diseases like fragile X syndrome, cystic fibrosis and myotonic muscular dystrophy. This dissertation concentrates on constructing high-resolution physical maps. It demonstrates how probabilistic modeling and statistical analysis can aid molecular geneticists in the tasks of planning, execution, and evaluation of physical maps of chromosomes and large chromosomal regions. The dissertation is divided into six chapters. Chapter 1 provides an introduction to the field of physical mapping, describing the role of physical mapping in gene isolation and ill past efforts at mapping chromosomal regions. The next two chapters review and extend known results on predicting progress in large mapping projects. Such predictions help project planners decide between various approaches and tactics for mapping large regions of the human genome. Chapter 2 shows how probability models have been used in the past to predict progress in mapping projects. Chapter 3 presents new results, based on stationary point process theory, for progress measures for mapping projects based on directed mapping strategies. Chapter 4 describes in detail the construction of all initial high-resolution physical map for human chromosome 19. This chapter introduces the probability and statistical models involved in map construction in the context of a large, ongoing physical mapping project. Chapter 5 concentrates on one such model, the trinomial model. This chapter contains new results on the large-sample behavior of this model, including distributional results, asymptotic moments, and detection error rates. In addition, it contains an optimality result concerning experimental procedures based on the trinomial model. The last chapter explores unsolved problems and describes future work

  4. Statistical methods in physical mapping

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, David O. [Univ. of California, Berkeley, CA (United States)

    1995-05-01

    One of the great success stories of modern molecular genetics has been the ability of biologists to isolate and characterize the genes responsible for serious inherited diseases like fragile X syndrome, cystic fibrosis and myotonic muscular dystrophy. This dissertation concentrates on constructing high-resolution physical maps. It demonstrates how probabilistic modeling and statistical analysis can aid molecular geneticists in the tasks of planning, execution, and evaluation of physical maps of chromosomes and large chromosomal regions. The dissertation is divided into six chapters. Chapter 1 provides an introduction to the field of physical mapping, describing the role of physical mapping in gene isolation and ill past efforts at mapping chromosomal regions. The next two chapters review and extend known results on predicting progress in large mapping projects. Such predictions help project planners decide between various approaches and tactics for mapping large regions of the human genome. Chapter 2 shows how probability models have been used in the past to predict progress in mapping projects. Chapter 3 presents new results, based on stationary point process theory, for progress measures for mapping projects based on directed mapping strategies. Chapter 4 describes in detail the construction of all initial high-resolution physical map for human chromosome 19. This chapter introduces the probability and statistical models involved in map construction in the context of a large, ongoing physical mapping project. Chapter 5 concentrates on one such model, the trinomial model. This chapter contains new results on the large-sample behavior of this model, including distributional results, asymptotic moments, and detection error rates. In addition, it contains an optimality result concerning experimental procedures based on the trinomial model. The last chapter explores unsolved problems and describes future work.

  5. Planetary Geologic Mapping Handbook - 2009

    Science.gov (United States)

    Tanaka, K. L.; Skinner, J. A.; Hare, T. M.

    2009-01-01

    Geologic maps present, in an historical context, fundamental syntheses of interpretations of the materials, landforms, structures, and processes that characterize planetary surfaces and shallow subsurfaces (e.g., Varnes, 1974). Such maps also provide a contextual framework for summarizing and evaluating thematic research for a given region or body. In planetary exploration, for example, geologic maps are used for specialized investigations such as targeting regions of interest for data collection and for characterizing sites for landed missions. Whereas most modern terrestrial geologic maps are constructed from regional views provided by remote sensing data and supplemented in detail by field-based observations and measurements, planetary maps have been largely based on analyses of orbital photography. For planetary bodies in particular, geologic maps commonly represent a snapshot of a surface, because they are based on available information at a time when new data are still being acquired. Thus the field of planetary geologic mapping has been evolving rapidly to embrace the use of new data and modern technology and to accommodate the growing needs of planetary exploration. Planetary geologic maps have been published by the U.S. Geological Survey (USGS) since 1962 (Hackman, 1962). Over this time, numerous maps of several planetary bodies have been prepared at a variety of scales and projections using the best available image and topographic bases. Early geologic map bases commonly consisted of hand-mosaicked photographs or airbrushed shaded-relief views and geologic linework was manually drafted using mylar bases and ink drafting pens. Map publishing required a tedious process of scribing, color peel-coat preparation, typesetting, and photo-laboratory work. Beginning in the 1990s, inexpensive computing, display capability and user-friendly illustration software allowed maps to be drawn using digital tools rather than pen and ink, and mylar bases became obsolete

  6. IHadoop: Asynchronous iterations for MapReduce

    KAUST Repository

    Elnikety, Eslam Mohamed Ibrahim

    2011-11-01

    MapReduce is a distributed programming frame-work designed to ease the development of scalable data-intensive applications for large clusters of commodity machines. Most machine learning and data mining applications involve iterative computations over large datasets, such as the Web hyperlink structures and social network graphs. Yet, the MapReduce model does not efficiently support this important class of applications. The architecture of MapReduce, most critically its dataflow techniques and task scheduling, is completely unaware of the nature of iterative applications; tasks are scheduled according to a policy that optimizes the execution for a single iteration which wastes bandwidth, I/O, and CPU cycles when compared with an optimal execution for a consecutive set of iterations. This work presents iHadoop, a modified MapReduce model, and an associated implementation, optimized for iterative computations. The iHadoop model schedules iterations asynchronously. It connects the output of one iteration to the next, allowing both to process their data concurrently. iHadoop\\'s task scheduler exploits inter-iteration data locality by scheduling tasks that exhibit a producer/consumer relation on the same physical machine allowing a fast local data transfer. For those iterative applications that require satisfying certain criteria before termination, iHadoop runs the check concurrently during the execution of the subsequent iteration to further reduce the application\\'s latency. This paper also describes our implementation of the iHadoop model, and evaluates its performance against Hadoop, the widely used open source implementation of MapReduce. Experiments using different data analysis applications over real-world and synthetic datasets show that iHadoop performs better than Hadoop for iterative algorithms, reducing execution time of iterative applications by 25% on average. Furthermore, integrating iHadoop with HaLoop, a variant Hadoop implementation that caches

  7. IHadoop: Asynchronous iterations for MapReduce

    KAUST Repository

    Elnikety, Eslam Mohamed Ibrahim; El Sayed, Tamer S.; Ramadan, Hany E.

    2011-01-01

    MapReduce is a distributed programming frame-work designed to ease the development of scalable data-intensive applications for large clusters of commodity machines. Most machine learning and data mining applications involve iterative computations over large datasets, such as the Web hyperlink structures and social network graphs. Yet, the MapReduce model does not efficiently support this important class of applications. The architecture of MapReduce, most critically its dataflow techniques and task scheduling, is completely unaware of the nature of iterative applications; tasks are scheduled according to a policy that optimizes the execution for a single iteration which wastes bandwidth, I/O, and CPU cycles when compared with an optimal execution for a consecutive set of iterations. This work presents iHadoop, a modified MapReduce model, and an associated implementation, optimized for iterative computations. The iHadoop model schedules iterations asynchronously. It connects the output of one iteration to the next, allowing both to process their data concurrently. iHadoop's task scheduler exploits inter-iteration data locality by scheduling tasks that exhibit a producer/consumer relation on the same physical machine allowing a fast local data transfer. For those iterative applications that require satisfying certain criteria before termination, iHadoop runs the check concurrently during the execution of the subsequent iteration to further reduce the application's latency. This paper also describes our implementation of the iHadoop model, and evaluates its performance against Hadoop, the widely used open source implementation of MapReduce. Experiments using different data analysis applications over real-world and synthetic datasets show that iHadoop performs better than Hadoop for iterative algorithms, reducing execution time of iterative applications by 25% on average. Furthermore, integrating iHadoop with HaLoop, a variant Hadoop implementation that caches

  8. A road map for implementing systems engineering

    Energy Technology Data Exchange (ETDEWEB)

    Dean, F.F. [Sandia National Labs., Albuquerque, NM (United States). New Mexico Weapons Systems Engineering Center; Bentz, B.; Bahill, A.T. [Univ. of Arizona, Tucson, AZ (United States)

    1997-02-01

    Studies by academia, industry, and government indicate that applying a sound systems engineering process to development programs is an important tool for preventing cost and schedule overruns and performance deficiencies. There is an enormous body of systems engineering knowledge. Where does one start? How can the principles of systems engineering be applied in the Sandia environment? This road map is intended to be an aid to answering these questions.

  9. Multimodal Sensor-Based Semantic 3D Mapping for a Large-Scale Environment

    OpenAIRE

    Jeong, Jongmin; Yoon, Tae Sung; Park, Jin Bae

    2018-01-01

    Semantic 3D mapping is one of the most important fields in robotics, and has been used in many applications, such as robot navigation, surveillance, and virtual reality. In general, semantic 3D mapping is mainly composed of 3D reconstruction and semantic segmentation. As these technologies evolve, there has been great progress in semantic 3D mapping in recent years. Furthermore, the number of robotic applications requiring semantic information in 3D mapping to perform high-level tasks has inc...

  10. Analysis of ONKALO water leakage mapping results

    International Nuclear Information System (INIS)

    Ahokas, H.; Nummela, J; Turku, J.

    2014-04-01

    As part of the programme for the final disposal of spent nuclear fuel, an analysis has been compiled of water leakage mapping performed in ONKALO. Leakage mapping is part of the Olkiluoto Monitoring Programme (OMO) and the field work has been carried out by Posiva Oy. The main objective of the study is to analyse differences detected between mapping campaigns carried out typically twice a year in 2005-2012. Differences were estimated to be caused by the differences in groundwater conditions caused by seasonal effects or by differences between the years. The effect of technical changes like shotcreting, postgrouting, ventilation etc. on the results was also studied. The development of the visualisation of mapping results was also an objective of this work. Leakage mapping results have been reported yearly in the monitoring reports of Hydrology with some brief comments on the detected differences. In this study, the development of the total area and the number of different leakages as well as the correlation of changes with shotcreting and grouting operations were studied. In addition, traces of fractures on tunnel surfaces, and the location of rock bolts and drain pipes were illustrated together with leakage mapping. In water leakage mapping, the tunnel surfaces are visually mapped to five categories: dry, damp, wet, dripping and flowing. Major changes were detected in the total area of damp leakages. It is likely that the increase has been caused by the condensation of warm ventilation air on the tunnel surfaces and the corresponding decrease by the evaporation of moisture into the dry ventilation air. Shotcreting deep in ONKALO may also have decreased the total area of damp leakages. Changes in the total area and number of wet leakages correlate at least near the surface with differences in yearly precipitation. It is possible that strong rains have also caused a temporary increase in wet leakages. Dripping and wet leakages have been observed on average more

  11. Analysis of ONKALO water leakage mapping results

    Energy Technology Data Exchange (ETDEWEB)

    Ahokas, H.; Nummela, J; Turku, J. [Poeyry Finland Oy, Vantaa (Finland)

    2014-04-15

    As part of the programme for the final disposal of spent nuclear fuel, an analysis has been compiled of water leakage mapping performed in ONKALO. Leakage mapping is part of the Olkiluoto Monitoring Programme (OMO) and the field work has been carried out by Posiva Oy. The main objective of the study is to analyse differences detected between mapping campaigns carried out typically twice a year in 2005-2012. Differences were estimated to be caused by the differences in groundwater conditions caused by seasonal effects or by differences between the years. The effect of technical changes like shotcreting, postgrouting, ventilation etc. on the results was also studied. The development of the visualisation of mapping results was also an objective of this work. Leakage mapping results have been reported yearly in the monitoring reports of Hydrology with some brief comments on the detected differences. In this study, the development of the total area and the number of different leakages as well as the correlation of changes with shotcreting and grouting operations were studied. In addition, traces of fractures on tunnel surfaces, and the location of rock bolts and drain pipes were illustrated together with leakage mapping. In water leakage mapping, the tunnel surfaces are visually mapped to five categories: dry, damp, wet, dripping and flowing. Major changes were detected in the total area of damp leakages. It is likely that the increase has been caused by the condensation of warm ventilation air on the tunnel surfaces and the corresponding decrease by the evaporation of moisture into the dry ventilation air. Shotcreting deep in ONKALO may also have decreased the total area of damp leakages. Changes in the total area and number of wet leakages correlate at least near the surface with differences in yearly precipitation. It is possible that strong rains have also caused a temporary increase in wet leakages. Dripping and wet leakages have been observed on average more

  12. Visualizing Dynamic Data with Maps.

    Science.gov (United States)

    Mashima, Daisuke; Kobourov, Stephen G; Hu, Yifan

    2012-09-01

    Maps offer a familiar way to present geographic data (continents, countries), and additional information (topography, geology), can be displayed with the help of contours and heat-map overlays. In this paper, we consider visualizing large-scale dynamic relational data by taking advantage of the geographic map metaphor. We describe a map-based visualization system which uses animation to convey dynamics in large data sets, and which aims to preserve the viewer's mental map while also offering readable views at all times. Our system is fully functional and has been used to visualize user traffic on the Internet radio station last.fm, as well as TV-viewing patterns from an IPTV service. All map images in this paper are available in high-resolution at [1] as are several movies illustrating the dynamic visualization.

  13. Knowledge Map of Facilities Management

    DEFF Research Database (Denmark)

    Nenonen, Suvi; Jensen, Per Anker; Lindahl, Göran

    2014-01-01

    both the research community and FM-practitioners can develop new models for identifying knowledge needs and gaps and to improve knowledge sharing and knowledge flow and thus the fulfilment of their mission and goals. Knowledge maps can also help in organizing research activities and analysing......Purpose This paper aims to draft a knowledge map of the fragmented and multidisciplinary research of and relevant to FM. Facilities management knowledge map is a tool for presenting what relevant data and knowledge, a.k.a. knowledge, resides in different disciplines. Knowledge mapping is a step...... in creating an inventory of knowledge (i.e. the knowledge base) and developing/improving the processes of knowledge sharing in research, education and practice. Theory Knowledge mapping is discussed in terms of knowledge management. The research is connected to knowledge mapping in the facilities management...

  14. Quantum Programs as Kleisli Maps

    Directory of Open Access Journals (Sweden)

    Abraham Westerbaan

    2017-01-01

    Full Text Available Furber and Jacobs have shown in their study of quantum computation that the category of commutative C*-algebras and PU-maps (positive linear maps which preserve the unit is isomorphic to the Kleisli category of a comonad on the category of commutative C*-algebras with MIU-maps (linear maps which preserve multiplication, involution and unit. [Furber and Jacobs, 2013] In this paper, we prove a non-commutative variant of this result: the category of C*-algebras and PU-maps is isomorphic to the Kleisli category of a comonad on the subcategory of MIU-maps. A variation on this result has been used to construct a model of Selinger and Valiron's quantum lambda calculus using von Neumann algebras. [Cho and Westerbaan, 2016

  15. Synchronizability of coupled PWL maps

    International Nuclear Information System (INIS)

    Polynikis, A.; Di Bernardo, M.; Hogan, S.J.

    2009-01-01

    In this paper we discuss the phenomenon of synchronization of chaotic systems in the case of coupled piecewise linear (PWL) continuous and discontinuous one-dimensional maps. We present numerical results for two examples of coupled systems consisting of two PWL maps. We illustrate how the coupled system can achieve synchronization and discuss the nature of the bifurcation that occurs at a critical value of the coupling strength. We then determine this critical coupling using linear stability analysis. We discuss the effects of variation of the parameters of the PWL maps on the critical coupling and present different bifurcation scenarios obtained for different sets of values of these parameters. Finally, we discuss an extension of our work to the synchronizability of networks consisting of two or more PWL maps. We show how the synchronizability of a network of PWL maps can be improved by tuning the map parameters.

  16. Imagining Geographies, Mapping Identities

    Directory of Open Access Journals (Sweden)

    Matthew Graves

    2015-03-01

    Full Text Available The ambition of this issue of Portal is to reach across the methodological boundaries of history, politics, literature and geography to apply their complementary perspectives to the study of identity and its relation to space and place, an aim that involves attempting to identify the many different ways the notoriously slippery concepts of identity and geography may intersect. For this issue we have selected articles that cast a fresh perspective on two areas where identity and geography intersect: the construction of identity through the imaginative recreation of place in literature: Mapping Literary Spaces; and the study of the shifting relationships of centre and periphery, exclusion and inclusion in urban settings and geopolitical confrontations: Social and Political Peripheries. Gerard Toal has written that geography is not a noun but a verb: it does not describe what space is but studies what we do with space, imaginatively and politically. The articles in this issue illustrate the exercise of the literary and political imagination and the role of materiality and memory in the creation of geographic representation. They show too a new awareness of the centrality of space in the constitution of identities, and the need for a new geocritical reading of its discourse, as the interrelations of place and community are played out on the many scales of social and political life, from the local to the global.   The special issue is organised thus: Introduction Matthew Graves (Aix-Marseille University & Liz Rechniewski (Sydney University: “Imagining Geographies, Mapping Identities.” I. Mapping Literary Spaces - Isabelle Avila (University of Paris XIII, "Les Cartes de l'Afrique au XIXe siècle et Joseph Conrad : Perceptions d'une Révolution Cartographique." - Daniela Rogobete (University of Craiova, "Global vs Glocal: Dimensions of the post-1981 Indian English Novel." II. Social and Political Peripheries - Elizabeth Rechniewski (Sydney

  17. A fast image encryption algorithm based on chaotic map

    Science.gov (United States)

    Liu, Wenhao; Sun, Kehui; Zhu, Congxu

    2016-09-01

    Derived from Sine map and iterative chaotic map with infinite collapse (ICMIC), a new two-dimensional Sine ICMIC modulation map (2D-SIMM) is proposed based on a close-loop modulation coupling (CMC) model, and its chaotic performance is analyzed by means of phase diagram, Lyapunov exponent spectrum and complexity. It shows that this map has good ergodicity, hyperchaotic behavior, large maximum Lyapunov exponent and high complexity. Based on this map, a fast image encryption algorithm is proposed. In this algorithm, the confusion and diffusion processes are combined for one stage. Chaotic shift transform (CST) is proposed to efficiently change the image pixel positions, and the row and column substitutions are applied to scramble the pixel values simultaneously. The simulation and analysis results show that this algorithm has high security, low time complexity, and the abilities of resisting statistical analysis, differential, brute-force, known-plaintext and chosen-plaintext attacks.

  18. Digital soil mapping: strategy for data pre-processing

    Directory of Open Access Journals (Sweden)

    Alexandre ten Caten

    2012-08-01

    Full Text Available The region of greatest variability on soil maps is along the edge of their polygons, causing disagreement among pedologists about the appropriate description of soil classes at these locations. The objective of this work was to propose a strategy for data pre-processing applied to digital soil mapping (DSM. Soil polygons on a training map were shrunk by 100 and 160 m. This strategy prevented the use of covariates located near the edge of the soil classes for the Decision Tree (DT models. Three DT models derived from eight predictive covariates, related to relief and organism factors sampled on the original polygons of a soil map and on polygons shrunk by 100 and 160 m were used to predict soil classes. The DT model derived from observations 160 m away from the edge of the polygons on the original map is less complex and has a better predictive performance.

  19. Empirical PPGIS/PGIS mapping of ecosystem services

    DEFF Research Database (Denmark)

    Brown, Gregory G; Fagerholm, Nora

    2015-01-01

    demonstrate high potential for the identification of ecosystem services, especially cultural services, there has been no review to evaluate the methods to identify best practice. Through examination of peer-reviewed, empirical PPGIS/PGIS studies, we describe the types of ecosystem services mapped, the spatial...... of experimental design and long-term case studies where the influence of mapped ecosystem services on land use decisions can be assessed....... mapping methods, the sampling approaches and range of participants, the types of spatial analyses performed, and the methodological trade-offs associated with each PPGIS/PGIS mapping approach. We found that multiple methods were implemented in nearly 30 case studies worldwide with the mapping of cultural...

  20. Exploiting Surroundedness for Saliency Detection: A Boolean Map Approach.

    Science.gov (United States)

    Zhang, Jianming; Sclaroff, Stan

    2016-05-01

    We demonstrate the usefulness of surroundedness for eye fixation prediction by proposing a Boolean Map based Saliency model (BMS). In our formulation, an image is characterized by a set of binary images, which are generated by randomly thresholding the image's feature maps in a whitened feature space. Based on a Gestalt principle of figure-ground segregation, BMS computes a saliency map by discovering surrounded regions via topological analysis of Boolean maps. Furthermore, we draw a connection between BMS and the Minimum Barrier Distance to provide insight into why and how BMS can properly captures the surroundedness cue via Boolean maps. The strength of BMS is verified by its simplicity, efficiency and superior performance compared with 10 state-of-the-art methods on seven eye tracking benchmark datasets.