Mark I 1/5-scale boiling water reactor pressure suppression experiment. Quick-look report for test numbers 1.0(a) and 1.0(b) performed on March 4 and 8, 1977

International Nuclear Information System (INIS)

McCauley, E.W.; Pitts, J.H.

1977-01-01

The experimental results obtained from pressure suppression experiment numbers 1.0(a) and 1.0(b) that were performed on the Lawrence Livermore Laboratory's 1 / 5 -scale boiling water reactor (BWR) Mark I pressure suppression experimental facility are summarized

Fail or flourish? Cognitive appraisal moderates the effect of solo status on performance.

Science.gov (United States)

White, Judith B

2008-09-01

When everyone in a group shares a common social identity except one individual, the one who is different from the majority has solo status. Solo status increases one's visibility and performance pressure, which may result in stress. Stress has divergent effects on performance, and individuals' response to stressful situations is predicted by their cognitive appraisal (challenge or threat) of the situation. Two experiments test the hypothesis that cognitive appraisal moderates the effect of solo status on performance. Experiment 1 finds that at relatively high appraisal levels (resources exceed demands), solo status improves men's and women's performance; at relatively low appraisal levels, solo status hurts performance. Experiment 2 replicates this effect for solo status based on minimal group assignment. Results suggest that for individuals who feel challenged and not threatened by their work, it may help to be a solo.

Prediction of 90 Day and Overall Survival after Chemoradiotherapy for Lung Cancer: Role of Performance Status and Body Composition.

Science.gov (United States)

Bowden, J C S; Williams, L J; Simms, A; Price, A; Campbell, S; Fallon, M T; Fearon, K C H

2017-09-01

If appropriate patients are to be selected for lung cancer treatment, an understanding of who is most at risk of adverse outcomes after treatment is needed. The aim of the present study was to identify predictive factors for 30 and 90 day mortality after chemoradiotherapy (CRT), and factors that were prognostic for overall survival. A retrospective cohort study of 194 patients with lung cancer who had undergone CRT in South East Scotland from 2008 to 2010 was undertaken. Gender, age, cancer characteristics, weight loss, body mass index (BMI), performance status (Eastern Cooperative Oncology Group; ECOG) and computed tomography-derived body composition variables were examined for prognostic significance using Cox's proportional hazards model and logistic regression. The median overall survival was 19 months (95% confidence interval 16.3, 21.7). Four of 194 patients died within 30 days of treatment completion, for which there were no independent predictive variables; 22/194 (11%) died within 90 days of treatment completion. BMI < 20 and ECOG performance status ≥2 were independent predictors of death within 90 days of treatment completion (P = 0.001 and P = 0.004, respectively). Patients with either BMI < 20 or ECOG performance status ≥ 2 had an odds ratio of death within 90 days of 5.97 (95% confidence interval 2.20, 16.19), rising to an odds ratio of 13.27 (1.70, 103.47) for patients with both BMI < 20 and ECOG performance status ≥ 2. Patients with low muscle attenuation had significantly reduced overall survival (P = 0.004); individuals with low muscle attenuation had a median survival of 15.2 months (95% confidence interval 12.7, 17.7) compared with 23.0 months (95% confidence interval 18.3, 27.8) for those with high muscle attenuation, equating to a hazard ratio of death of 1.62 (95% confidence interval 1.17, 2.23, P = 0.003). Poor performance status, low BMI and low muscle attenuation identify patients at increased risk of premature death after

Dielectric and magnetic properties of Ba-, La- and Pb-doped Bi0.8Gd0.1M0.1Fe0.9Ti0.1O3 perovskite ceramics

Directory of Open Access Journals (Sweden)

Radheshyam Rai

2014-04-01

Full Text Available The multiferroic Bi0.8Gd0.1M0.1Fe0.9Ti0.1O3, (where M = Ba (DB, La (DL and Pb (DP has been synthesized by using solid-state reaction technique. Effects of Ba, La and Pb substitution on the structure, electrical and ferroelectric properties of Bi0.8Gd0.1M0.1Fe0.9Ti0.1O3 samples have been studied by performing X-ray diffraction, dielectric and magnetic measurements. The crystal structures of the ceramic samples have a tetragonal phase. The vibrating sample magnetometer (VSM measurement shows a significant change in the magnetic properties of Ba-doped Bi0.8Gd0.1M0.1Fe0.9Ti0.1O3 as compared to La- and Pb-doped ceramics. It is seen that coercive field (HC and remanent magnetization (MR increases with Ba-doped ceramics but decreases for La- and Pb-doped ceramics.

Microstructural evolution of nanosized Ce0.8Gd0.2O1.9/Ni infiltrate in a Zr0.84Y0.16O1.92-Sr0.94Ti0.9Nb0.1O3-δ based SOFC anode under electrochemical evaluation

DEFF Research Database (Denmark)

Zhang, Wei; Kuhn, Luise Theil; Ramos, Tania

are of paramount importance for performance and performance stability. Therefore an accurate understanding of the microstructure evolution during electrochemical operation will facilitate evaluating performances of SOFC anodes, and in turn optimize its design. Here we report a wealth of microstructural...... investigations of Ce0.8Gd0.2O1.9/Ni (hereafter CGO/Ni)-infiltrated Zr0.84Y0.16O1.92 composited Sr0.94Ti0.9Nb0.1O3-δ (STN94/8YSZ) anode in a symmetric cell design under a short electrochemical evaluation test (fingerprint test), applying electrochemical impedance spectroscopy (EIS) at mild 3% H2O/H2 and harsh 50...

Status of the Tevatron CDF and D0 experiments

International Nuclear Information System (INIS)

Rolli, Simona

2010-01-01

The status of the Tevatron Collider is reviewed and highlights of the rich physics program carried out by the CDF and D0 experiments are presented. The Tevatron Collider has been performing remarkably well in the past few years and it is continuing to deliver record luminosity. The machine collides proton and anti-proton beams at an energy in the center of mass of 1.96 TeV, with average peak luminosity of 300E30 cm -2 s -1 . The total delivered luminosity is slightly above 9 fb -1 . The CDF and D0 experiments have been collecting data with an average efficiency of 90%, while the experiments have enjoyed an annual doubling of the integrated luminosity delivered and recorded. This has led to an avalanche of new results from areas as diverse as QCD, top, searches for new physics and the area of electroweak symmetry breaking with particular focus on direct searches for the Higgs boson. The physics reach of the Tevatron is built on a mountain of measurements that confirm the ability of the Tevatron collaborations to use their detectors to discover new particles. Each measurement is of itself a significant result. Measurements begin with the largest cross section processes, those of B physics, but move on to processes with small branching ratios and backgrounds that are hard to distinguish from the signal. The measurement of Bs oscillations demonstrates the performance of the silicon tracking and vertexing. Discovery of single top production, WZ production, and evidence for the ZZ production in both leptonic and now hadronic modes provide the final base camp from which the Higgs summit is in sight. Processes such as single top and ZZ act as important messengers heralding the impending arrival of the Higgs. This journey through lower and lower cross section processes represents our approach to provide convincing evidence of these processes, first as discovery then as measurements that constrain the Standard Model.

Factoring socioeconomic status into cardiac performance profiling for hospitals: does it matter?

Science.gov (United States)

Alter, David A; Austin, Peter C; Naylor, C David; Tu, Jack V

2002-01-01

Critics of "scorecard medicine" often highlight the incompleteness of risk-adjustment methods used when accounting for baseline patient differences. Although socioeconomic status is a highly important determinant of adverse outcome for patients admitted to the hospital with acute myocardial infarction, it has not been used in most risk-adjustment models for cardiovascular report cards. To determine the incremental impact of socioeconomic status adjustments on age, sex, and illness severity for hospital-specific 30-day mortality rates after acute myocardial infarction. The authors compared the absolute and relative hospital-specific 30-day acute myocardial infarction mortality rates in 169 hospitals throughout Ontario between April 1, 1994 and March 31, 1997. Patient socioeconomic status was characterized by median neighborhood income using postal codes and 1996 Canadian census data. They examined two risk-adjustment models: the first adjusted for age, sex, and illness severity (standard), whereas the second adjusted for age, sex, illness severity, and median neighborhood income level (socioeconomic status). There was an extremely strong correlation between 'standard' and 'socioeconomic status' risk-adjusted mortality rates (r = 0.99). Absolute differences in 30-day risk-adjusted mortality rates between the socioeconomic status and standard risk-adjustment models were small (median, 0.1%; 25th-75th percentile, 0.1-0.2). The agreement in the quintile rankings of hospitals between the socioeconomic status and standard risk-adjustment models was high (weighted kappa = 0.93). Despite its importance as a determinant of patient outcomes, the effect of socioeconomic status on hospital-specific mortality rates over and above standard risk-adjustment methods for acute myocardial infarction hospital profiling in Ontario was negligible.

Low vitamin D status is associated with reduced muscle mass and impaired physical performance in frail elderly people.

Science.gov (United States)

Tieland, M; Brouwer-Brolsma, E M; Nienaber-Rousseau, C; van Loon, L J C; De Groot, L C P G M

2013-10-01

Serum 25-hydroxyvitamin D (25(OH)D) status has been associated with muscle mass, strength and physical performance in healthy elderly people. Yet, in pre-frail and frail elderly people this association has not been studied. The objective of this study was to explore the association between vitamin D intake and serum 25(OH)D status with muscle mass, strength and physical performance in a pre-frail and frail elderly population. This cross-sectional study included 127 pre-frail and frail elderly people in The Netherlands. Whole body and appendicular lean mass (ALM) (dual energy X-ray absorptiometry), leg strength (one repetition maximum), handgrip strength and physical performance (short physical performance battery) were measured, and blood samples were collected for the assessment of serum 25(OH)D status (liquid chromatography-tandem mass spectrometry). In addition, habitual dietary intake (3-day food records) and physical activity data (accelerometers) were collected. In total, 53% of the participants had a serum 25(OH)D level below 50  nmol/l. After adjustment for confounding factors, 25(OH)D status was associated with ALM (β=0.012, P=0.05) and with physical performance (β=0.020, PVitamin D intake was associated with physical performance (β=0.18, P0.05). In this frail elderly population, 25(OH)D status is low and suggests a modest association with reduced ALM and impaired physical performance. In addition, vitamin D intake tended to be associated with impaired physical performance. Our findings highlight the need for well-designed intervention trials to assess the impact of vitamin D supplementation on 25(OH)D status, muscle mass and physical performance in pre-frail and frail elderly people.

Development Status of Diffusion Code RAST-K 2.0 at UNIST

Energy Technology Data Exchange (ETDEWEB)

Park, Minyong; Zheng, Youqi; Choe, Jiwon; Zhang, Peng; Lee, Deokjung [UNIST, Ulsan (Korea, Republic of); Lee, Eunki; Shin, Hocheol [KHNP Central Research Institute, Daejeon (Korea, Republic of)

2016-10-15

The non-linear scheme was used based on the 2-group CMFD and a three dimensional multi -group unified nodal method (UNM). To consider the history effects, the main heavy isotopes were tracked by micro-depletion module using CRAM. The simplified 1-D single channel thermal hydraulic solver from nTACER is implemented. The θ method was adopted in the transient calculation. To get detailed pin-wise power and burnup distribution, Pin power reconstruction module was implemented. Also automatic control logic to calculate MTC, FTC, control rod worth was implemented. To perform multicycle analysis, restart and shuffling/rotation module has been implemented. To link between CASMO-4E and RAST-K 2.0, CATORA (CASMO TO RAST-K 2.0) code was developed. Unlike the other diffusion codes, RAST-K 2.0 depletion module uses CRAM and extended depletion chain for fission products. Most lattice codes give cumulative fission yield of Pm-149 without considering Pm-148 and Pm-149 capture reaction which will lead to the increase of Sm-149 number density. This paper reports the status of RAST-K 2.0 code development at UNIST. The new code applies a new kernel based on the two-node UNM with CMFD, and θ method for kinetic calculation. Also, the microdepletion calculation is used to consider the history effects. And other modules and functions also implemented such as pin power reconstruction, branch calculation, restart, multi-cycle, and 1-D single channel T/H solver.

Enhanced electrochemical performance of LiNi_0_._8Co_0_._1_5Al_0_._0_5O_2 by nanoscale surface modification with Co_3O_4

International Nuclear Information System (INIS)

Huang, Yaqun; Huang, Yunhui; Hu, Xianluo

2017-01-01

Highlights: • Facile coating method to prepare Co_3O_4-modified NCA. • Co_3O_4 is uniformly coated on the surface of NCA. • The nanolayer coating protects the surface of NCA during Li cycling. • Co_3O_4-modified NCA exhibits enhanced cyclability and rate capability. - Abstract: LiNi_0_._8Co_0_._1_5Al_0_._0_5O_2 (NCA) has attracted much attention because of its high capacity and low cost. Herein, we report a facile wet-chemical route to prepare a Co_3O_4-modified NCA cathode material with enhanced electrochemical performance for lithium-ion batteries. The as-prepared Co_3O_4-coated NCA cathode material delivers a specific capacity of 207.6 mAh g"−"1 with an initial Coulombic efficiency of 90.8% at 0.1 C. The capacity retention of the Co_3O_4-coated NCA cathode material is as high as 91.6% at 1 C between the potential from 2.8 to 4.3 V after 100 cycles. More importantly, the capacity retention of the resulting Co_3O_4-coated NCA is higher than 94.7% after 100 cycles at 0.2 C. In addition, the Co_3O_4-coated NCA cathode material exhibits good rate capability, especially a high discharge capacity at a high current density. The outstanding electrochemical performance of Co_3O_4-coated NCA is assigned to the surface coating of Co_3O_4 that may react with lithium-containing impurities on the surface and decrease the charge-transfer resistance.

Status of the CUORE and results from the CUORE-0 neutrinoless double beta decay experiments

Science.gov (United States)

Sisti, M.; Artusa, D. R.; Avignone, F. T.; Azzolini, O.; Balata, M.; Banks, T. I.; Bari, G.; Beeman, J.; Bellini, F.; Bersani, A.; Biassoni, M.; Brofferio, C.; Bucci, C.; Cai, X. Z.; Camacho, A.; Caminata, A.; Canonica, L.; Cao, X. G.; Capelli, S.; Cappelli, L.; Carbone, L.; Cardani, L.; Casali, N.; Cassina, L.; Chiesa, D.; Chott, N.; Clemenza, M.; Copello, S.; Cosmelli, C.; Cremonesi, O.; Creswick, R. J.; Cushman, J. S.; Dafinei, I.; Dally, A.; Datskov, V.; Dell'Oro, S.; Deninno, M. M.; Di Domizio, S.; di Vacri, M. L.; Drobizhev, A.; Ejzak, L.; Fang, D. Q.; Farach, H. A.; Faverzani, M.; Fernandes, G.; Ferri, E.; Ferroni, F.; Fiorini, E.; Franceschi, M. A.; Freedman, S. J.; Fujikawa, B. K.; Giachero, A.; Gironi, L.; Giuliani, A.; Gorla, P.; Gotti, C.; Gutierrez, T. D.; Haller, E. E.; Han, K.; Heeger, K. M.; Hennings-Yeomans, R.; Hickerson, K. P.; Huang, H. Z.; Kadel, R.; Keppel, G.; Kolomensky, Yu. G.; Li, Y. L.; Ligi, C.; Lim, K. E.; Liu, X.; Ma, Y. G.; Maiano, C.; Maino, M.; Martinez, M.; Maruyama, R. H.; Mei, Y.; Moggi, N.; Morganti, S.; Napolitano, T.; Nastasi, M.; Nisi, S.; Nones, C.; Norman, E. B.; Nucciotti, A.; O'Donnell, T.; Orio, F.; Orlandi, D.; Ouellet, J. L.; Pagliarone, C. E.; Pallavicini, M.; Palmieri, V.; Pattavina, L.; Pavan, M.; Pedretti, M.; Pessina, G.; Pettinacci, V.; Piperno, G.; Pira, C.; Pirro, S.; Pozzi, S.; Previtali, E.; Rosenfeld, C.; Rusconi, C.; Sala, E.; Sangiorgio, S.; Scielzo, N. D.; Smith, A. R.; Taffarello, L.; Tenconi, M.; Terranova, F.; Tian, W. D.; Tomei, C.; Trentalange, S.; Ventura, G.; Vignati, M.; Wang, B. S.; Wang, H. W.; Wielgus, L.; Wilson, J.; Winslow, L. A.; Wise, T.; Woodcraft, A.; Zanotti, L.; Zarra, C.; Zhang, G. Q.; Zhu, B. X.; Zucchelli, S.

2016-04-01

CUORE is a 741 kg array of TeO2 bolometers for the search of neutrinoless double beta decay of 130Te. The detector is being constructed at the Laboratori Nazionali del Gran Sasso, Italy, where it will start taking data in 2015. If the target background of 0.01 counts / (keV ṡkg ṡy) will be reached, in five years of data taking CUORE will have a 1σ half life sensitivity of 1026 y. CUORE-0 is a smaller experiment constructed to test and demonstrate the performances expected for CUORE. The detector is a single tower of 52 CUORE-like bolometers that started taking data in spring 2013. The status and perspectives of CUORE will be discussed, and the first CUORE-0 data will be presented.

Status and Performance of University Librarians in Uganda ...

African Journals Online (AJOL)

It was also found that the status of university librarians is a significant predictor of their performance. Therefore, the paper urges university administrators in the country to re-examine the status accorded to their librarians because it is an important ingredient in their performance. Keywords: Library management; Performance ...

Effects of nutritional and psychological status of the patients with advanced stomach cancer on physical performance status.

Science.gov (United States)

Tian, Jun; Chen, Zhen-chun; Hang, Li-Fang

2009-10-01

The aim of this study was to assess the associations between coping mode, nutritional status, and psychological status and performance status of the patients with advanced stomach cancer. An epidemiological survey was conducted among 233 patients with advanced stomach cancer in Fujian, China. In-person interviews were performed for the participants with respect to information of psychological status prior to chemotherapy, nutritional status during chemotherapy, and physical performance status after chemotherapy. Multivariate logistic regression analyses showed that the level of hemoglobin (HB), level of daily calorie intake, score of Depression Status Inventory (DSI), and score of confrontation subscale of Medical Coping Modes Questionnaire had a significant influence on performance status (P or =40 versus DSI score confrontation versus high score of confrontation, respectively. Depression, low score of "Confrontation", low levels of HB, and low level of daily calorie intake may be the risk factors of poor performance status of the patients with advanced stomach cancer.

High performance fuel electrodes fabricated by electroless plating of copper on BaZr0.8Ce0.1Y0.1O3-δ proton-conducting ceramic

Science.gov (United States)

Patki, Neil S.; Way, J. Douglas; Ricote, Sandrine

2017-10-01

The stability of copper at high temperatures in reducing and hydrocarbon-containing atmospheres makes it a good candidate for fabricating fuel electrodes on proton-conducting ceramics, such as BaZr0.9-xCexY0.1O3-δ (BZCY). In this work, the electrochemical performance of Cu-based electrodes fabricated by electroless plating (ELP) on BaZr0.8Ce0.1Y0.1O3-δ is studied with impedance spectroscopy. Three activation catalysts (Pd, Ru, and Cu) are investigated and ELP is compared to a commercial Cu paste (ESL 2312-G) for electrode fabrication. The area specific resistances (ASR) for Pd, Ru, and Cu activations at 700 °C in moist 5% H2 in Ar are 2.1, 3.2, and 13.4 Ω cm2, respectively. That is a 1-2 orders of magnitude improvement over the commercial Cu paste (192 Ω cm2). Furthermore, the ASR has contributions from electrode processes and charge transfer at the electrode/electrolyte interface. Additionally, the morphology of the as-fabricated electrode is unaffected by the activation catalyst. However, heat treatment at 750 °C in H2 for 24 h leads to sintering and large reorganization of the electrode fabricated with Cu activation (micron sized pores seen in the tested sample), while Pd and Ru activations are immune to such reorganization. Thus, Pd and Ru are identified as candidates for future work with improvements to charge transfer required for the former, and better electrode processes required for the latter.

Range performance calculations using the NVEOL-Georgia Tech Research Institute 0.1- to 100-GHz radar performance model

Science.gov (United States)

Rodak, S. P.; Thomas, N. I.

1983-05-01

A computer model that can be used to calculate radar range performance at any frequency in the 0.1-to 100-GHz electromagnetic spectrum is described. These different numerical examples are used to demonstrate how to use the radar range performance model. Input/output documentation are included for each case that was run on the MERADCOM CDC 6600 computer at Fort Belvoir, Virginia.

Effect of carbon coating on electrochemical performance of Li1.048Mn0.381Ni0.286Co0.286O2 cathode material for lithium-ion batteries

International Nuclear Information System (INIS)

Shi, S.J.; Tu, J.P.; Mai, Y.J.; Zhang, Y.Q.; Gu, C.D.; Wang, X.L.

2012-01-01

Highlights: ► Carbon is coated on Li 1.048 Mn 0.381 Ni 0.286 Co 0.286 O 2 by a direct current magnetron sputtering. ► Cycle capability and rate performance are improved after carbon coating. ► A specific capacity of 145 mAh g −1 can be obtained at 5 C (1500 mA g −1 ). ► The coated layer restrains the reaction between the electrolyte and the electrode. - Abstract: Carbon-coated layered oxide Li 1.048 Mn 0.381 Ni 0.286 Co 0.286 O 2 is prepared by combining a co-precipitation and a direct current magnetron sputtering. TEM images show that the carbon layer is relatively well coated on the surface of oxide particles. The Li 1.048 Mn 0.381 Ni 0.286 Co 0.286 O 2 /C composite delivers an initial discharge capacity of 203.2 mAh g −1 between 2.5 and 4.5 V at 0.1 C, and 94% of the initial discharge capacity can be retained after 100 cycles. Moreover, the carbon-coated oxide exhibits noticeable high-rate capacity of 145 mAh g −1 at 5 C, much higher than the pristine one (103 mAh g −1 at 5 C). The improved discharge capacity and cycle performance are attributed to the carbon coating, which protects the Li-rich cathode material from reacting with the electrolyte and retarding the incrassation of SEI film on the surface of oxide particles.

Family affluence, socio - economic status and dietary habits of 1st year University students

Directory of Open Access Journals (Sweden)

Eirini Syligardou

2016-03-01

Full Text Available Introduction: Low socio-economic status (SES is associated with health risk behaviours contributing to the social inequalities in health. However, the associations of dietary habits with socio-economic status have not been investigated in emerging adulthood in detail yet. Aim: To investigate the associations of dietary habits with socio-economic status in 1st year undergraduate university students. Methods: This cross-sectional analysis draws data from the LATO study, a longitudinal study of all 1st year undergraduate students of TEI Crete during the academic year 2012/13 (Ν=1138, 54% girls, Mean age 18,31 years, response rate 96,7%. The consumption frequencies of fruits, vegetables, soft drinks, breakfast and delivery food were associated with the following socio-economic indicators: Family affluence (FAS II, paternal and maternal educational level and self-reported economic status. The SPSS v21.0 was used to perform logistic regression models after adjusting for potential confounders. Results: Only 24,9%, 12% and 17% of the students were consuming breakfast, fruits and vegetables, respectively, in a daily basis. Soft drinks were consumed daily by 6,1% of the participants but most of them consumed delivery/junk food less than 1/week (73,8%. Higher family affluence was associated with increased odds of consuming breakfast (OR=2,90, 95%CI=1,13-7,44, soft drinks (OR=8,10, 95%CI=1,38-47,68 and delivery/junk food (OR=2,44, 95%CI=1,27-4,70 in boys. High paternal educational level was associated in a protective way with boys’ consumption of delivery food (OR=0,42, 95%CI=0,18-0,95 and soft drinks (OR=0,19, 95%CI=0,05-0,72. Fruits and vegetables consumption was not associated with any SES indicator. Conclusions: The majority of 1st year university students were not following current diet recommendations irrespective of SES. Interventions targeting eating behaviours are needed at higher education institutes.

Effects of nutritional status on academic performance of Malaysian primary school children.

Science.gov (United States)

Zaini, M Z Anuar; Lim, C T; Low, W Y; Harun, F

2005-01-01

Numerous factors are known to affect the academic performance of students. These include prenatal conditions, birth conditions, postnatal events, nutritional, socio-economic factors and environmental factors. This paper examines the nutritional status and its relationship with academic performance of 9-10 years old primary school children recruited randomly in Selangor, Malaysia. A standard self-administered questionnaire was utilized to obtain pertinent information and a face-to-face interview was also conducted with the parents. Results of the academic performances were extracted from the students' report cards. The intellectual performance was assessed using Raven's Coloured Progressive Matrices. Physical examination was also conducted on these students by doctors. Overall 1,405 students and 1,317 parents responded to the survey. Of these 83.6% were Malays, 11.6% Indians, and 4.2% Chinese. The majority of them (82.9%) were from urban areas. The female: male ratio was 51:49; mean age was 9.71 years. The mean height and weight were 32.3 kg and 135.2 cm respectively. Their mean BMI was 17.42 kg/cm2, with 0.9% underweight, 76.3% normal BMI, 16.3% overweight, and 6.3% obese. Academic performance was significantly correlated with breast feeding, income and educational level of their parents, BMI, and whether they have been taking breakfast. There was a weak correlation between presence of anaemia and intellectual performance. Improving the socio-economic status of the parents will lend a helping hand in the academic performance of the students. Since breast feeding is associated with better academic and intellectual performance it must be emphasized, particularly to expectant mothers in the antenatal clinics.

Physical activity and cohabitation status moderate the link between diabetes mellitus and cognitive performance in a community-dwelling elderly population in Germany

Science.gov (United States)

Buchmann, Nikolaus; Tegeler, Christina; Steinhagen-Thiessen, Elisabeth

2017-01-01

Aims/Hypothesis The increasing number of people with dementia and cognitive impairments makes it essential to detect and prevent modifiable risk factors of dementia. This study focuses on type 2 diabetes mellitus, especially on undiagnosed cases and their increased risk of cognitive impairment. Furthermore, the potential of physical activity and social integration to moderate the relation between diabetes and cognitive impairment is assessed. Methods We used cross-sectional data from 1299 participants of the Berlin Aging Study II (BASE-II) aged between 60 to 84 years and performed logistic regression models to analyze the association of diabetes status, physical activity, and cohabitation status with poor cognitive performance. Cognitive performance was measured with the Consortium to Establish a Registry for Alzheimer's Disease (CERAD)-Plus test battery. Results Undiagnosed diabetes (odds ratio (OR) = 2.12, p = 0.031), physical inactivity (OR = 1.43, p = 0.008) and non-cohabiting (OR = 1.58, p = 0.002) were associated with an increased likelihood of poor cognitive performance. The highest odds were observed in participants who suffered from undiagnosed or insulin-dependent diabetes and, in addition, were inactive (undiagnosed diabetes: OR = 3.44, p = 0.003; insulin-dependent diabetes: OR = 6.19, p = 0.019) or lived alone (undiagnosed diabetes: OR = 4.46, p = 0.006; insulin-dependent diabetes: OR = 6.46 p = 0.052). Physical activity and cohabiting appeared to be beneficial. Conclusions/Interpretation Physical activity and cohabitation status moderate the link between diabetes mellitus and cognitive performance. Special attention should be paid to undiagnosed and insulin-dependent diabetes cases, which have a particularly high risk of poor cognitive performance. PMID:29073237

Status of Breast Self-Examination Performance among Women Referring to Health Centers of Tabriz, Iran

Directory of Open Access Journals (Sweden)

Farshbaf-Khalili Azizeh

2014-07-01

Full Text Available Objective: Breast cancer is the most common type of cancer and the second principal cause of deaths from cancer in women. Breast self-examination (BSE is an inexpensive screening method and is carried out by women themselves. The purpose of this study was to examine the status of breast self-examination performance among women referring to health centers of Tabriz, Iran. Materials and Methods: This study was a descriptive/ cross-sectional research carried out on 400 women aged 20-50 years. The samples were recruited randomly from among female clients of health centers in Tabriz. A questionnaire and an observational checklist were used to elicit socio-demographic information and status of BSE performance among women. Content validity was used for validation and Cronbach’s alpha was calculated (0.80 for reliability of instrument. Descriptive and inferential statistics were used to analyze data through SPSS software. Results: The findings of this research showed that only 18.8% of women performed BSE. Among them, 46.67% performed BSE monthly, and 40% at the end of menstruation. The initiation age of BSE in 77% was between 21-30 years of age. It is considerable that 54.7% of them had received no advice on BSE from physicians and midwives. The majority of women did not perform the various steps of BSE. The quality of this screening was very desirable in 2 (0.5 %, desirable in 5 (1.3%, average in 19 (4.8%, undesirable in 36 (9%, and very undesirable in 338 (84.5% women. Chi-square test showed a significant relationship between the quality of BSE performance and level of education, employment, breastfeeding quality, and family history of breast cancer (P < 0.05. Conclusion: The findings showed that the status of BSE performance was very poor. Therefore, to encourage women to use BSE correctly and regularly, education programs should be performed through various media including television, radio, and leaflets. The role of Health personnel in this

Delivery strategies to optimize resource utilization and performance status for patients with advanced life-limiting illness: results from the "palliative care trial" [ISRCTN 81117481].

Science.gov (United States)

Abernethy, Amy P; Currow, David C; Shelby-James, Tania; Rowett, Debra; May, Frank; Samsa, Gregory P; Hunt, Roger; Williams, Helena; Esterman, Adrian; Phillips, Paddy A

2013-03-01

Evidence-based approaches are needed to improve the delivery of specialized palliative care. The aim of this trial was to improve on current models of service provision. This 2×2×2 factorial cluster randomized controlled trial was conducted at an Australian community-based palliative care service, allowing three simultaneous comparative effectiveness studies. Participating patients were newly referred adults, experiencing pain, and who were expected to live >48 hours. Patients enrolled with their general practitioners (GPs) and were randomized three times: 1) individualized interdisciplinary case conference including their GP vs. control, 2) educational outreach visiting for GPs about pain management vs. control, and 3) structured educational visiting for patients/caregivers about pain management vs. control. The control condition was current palliative care. Outcomes included Australia-modified Karnofsky Performance Status (AKPS) and pain from 60 days after randomization and hospitalizations. There were 461 participants: mean age 71 years, 50% male, 91% with cancer, median survival 179 days, and median baseline AKPS 60. Only 47% of individuals randomized to the case conferencing intervention received it; based on a priori-defined analyses, 32% of participants were included in final analyses. Case conferencing reduced hospitalizations by 26% (least squares means hospitalizations per patient: case conference 1.26 [SE 0.10] vs. control 1.70 [SE 0.13], P=0.0069) and better maintained performance status (AKPS case conferences 57.3 [SE 1.5] vs. control 51.7 [SE 2.3], P=0.0368). Among patients with declining function (AKPS performance status (AKPS case conferences 55.0 [SE 2.1] vs. control 46.5 [SE 2.9], P=0.0143; patient/caregiver education 54.7 [SE 2.8] vs. control 46.8 [SE 2.1], P=0.0206). Pain was unchanged. GP education did not change outcomes. A single case conference added to current specialized community-based palliative care reduced hospitalizations and better

Growth performance and oxidative status in piglets supplemented with verbascoside and teupolioside

Directory of Open Access Journals (Sweden)

G. Pastorelli

2010-04-01

Full Text Available Two hundred forty piglets, half female and half barrows, 8.1 ± 1.40 kg LW, were divided into 6 experimental groups and fed ad libitum with a diet supplemented with the following levels of antioxidants: 0 (CON + = positive control added with 100 mg lincomicine/kg, 5 (LT = low teupolioside or LV = low verbascoside, 10 (HT = high teupolioside; HV = high verbascoside; LT+LV mg/kg of diet for 56 days. Body weight and feed intake were recorded on d0, 14 and 56 of the trial. Ten piglets from each group were selected and blood collected by anterior vena cava puncture at 0, 14 and 56 d for reactive oxygen metabolite (ROMs determination. HV showed final weight higher than the other groups (P<0.05, and oxidative stability was improved by both integrations of verbascoside. These results support the view that Verbascoside influences the growth performances and oxidative status of piglets.

OCA/OCP Oracle database 11g all-in-one exam guide exams 1Z0-051, 1Z0-052, 1Z0-053

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Watson, John

2010-01-01

A Fully Integrated Study System for OCA Exams 1Z0-051 and 1Z0-052, and OCP Exam 1Z0-053 Prepare for the Oracle Certified Associate Administration I and SQL Fundamentals I exams and the Oracle Certified Professional Administration II exam with help from this exclusive Oracle Press guide. In each chapter, you'll find challenging exercises, practice questions, and a two-minute drill to highlight what you've learned. This authoritative guide will help you pass the test and serve as your essential on-the-job reference. Get complete coverage of all objectives for exams 1Z0-051, 1Z0-052, and 1Z0-053, including: Instance management Networking and storage Security SQL Oracle Recovery Manager and Oracle Flashback Oracle Automatic Storage Management Resource manager Oracle Scheduler Automatic workload repository Performance tuning And more On the CD-ROM: Three full practice exams Detailed answers and explanations Score report performance assessment tool Complete electronic book Three bonus exams available with free onli...

Dietary practices and nutritional status of 0-24-month-old children from Brazilian Amazonia.

Science.gov (United States)

Castro, T G; Baraldi, L G; Muniz, P T; Cardoso, M A

2009-12-01

To assess the nutritional status and dietary practices of 0-24-month-old children living in Brazilian Amazonia. Cross-sectional study. Information on children's dietary intakes was obtained from diet history data. Weight and length were measured for anthropometric evaluation. Fe status was assessed using fasting venous blood samples; Hb, serum ferritin and soluble transferrin receptor concentrations were measured. The towns of Assis Brasil and Acrelândia in the state of Acre, north-west Brazil. A total of sixty-nine randomly selected 0-24-month-old children. Of these children, 40.3 % were anaemic, 63.1 % were Fe-deficient, 28.1 % had Fe-deficiency anaemia and 11.6 % were stunted. Breast-feeding was initiated by 97.1 % of mothers, followed by early feeding with complementary foods. The dietary pattern reflected a high intake of carbohydrate-rich foods and cow's milk, with irregular intakes of fruit, vegetables and meat. All infants and 92.3 % of toddlers were at risk of inadequate Fe intakes. Fe from animal foods contributed on average 0.5 % and 14.3 % to total dietary Fe intake among infants and toddlers, respectively. Poor nutritional status and inadequate feeding practices in this study population reinforce the importance of exclusive breast-feeding during the first 6 months of life. Greater emphasis is required to improve the bioavailability of dietary Fe during complementary feeding practices.

Metal artifact suppression at the hip: diagnostic performance at 3.0 T versus 1.5 Tesla

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Nardo, Lorenzo; Han, Misung; Kretschmar, Martin; Krug, Roland; Link, Thomas M. [University of California San Francisco, Musculoskeletal and Quantitative Imaging Research, Department of Radiology and Biomedical Imaging, San Francisco, CA (United States); Guindani, Michele [The University of Texas MD Anderson Cancer Center, Department of Biostatistics - Unit 1411, Houston, TX (United States); Koch, Kevin [Medical College of Wisconsin, Department of Biophysics, Milwaukee, WI (United States); Medical College of Wisconsin, Department of Radiology, Milwaukee, WI (United States); Vail, Thomas [University of California San Francisco, Department of Orthopedic Surgery, San Francisco, CA (United States)

2015-11-15

This work aimed to compare the diagnostic performance of a metal artifact suppression sequence (MAVRIC-SL) for imaging of hip arthroplasties (HA) at 1.5 and 3 Tesla (T) field strength. Eighteen patients (10 females; aged 27-74) with HA were examined at 3.0 and 1.5 T within 3 weeks. The sequence protocol included 3D-MAVRIC-SL PD (coronal), 3D-MAVRIC-SL STIR (axial), FSE T1, FSE PD and STIR sequences. Anatomical structures and pathological findings were assessed independently by two radiologists. Artifact extent and technical quality (image quality, fat saturation and geometric distortion) were also evaluated. Findings at 1.5 and 3.0 T were compared using a Wilcoxon signed rank test. While image quality was better at 1.5 T, visualization of anatomic structures and clinical abnormalities was not significantly different using the two field strengths (p > 0.05). Fat suppression and amount of artifacts were significantly better at 1.5 T (p < 0.01). Inter- and intra-reader agreement for different anatomic details, image quality and visualization of abnormalities ranged from k = 0.62 to k = 1.00. MAVRIC-SL at 1.5 T had a comparable diagnostic performance when compared MAVRIC-SL at 3.0 T; however, the higher field strength was associated with larger artifacts, limited image quality and worse fat saturation. (orig.)

Metal artifact suppression at the hip: diagnostic performance at 3.0 T versus 1.5 Tesla

International Nuclear Information System (INIS)

Nardo, Lorenzo; Han, Misung; Kretschmar, Martin; Krug, Roland; Link, Thomas M.; Guindani, Michele; Koch, Kevin; Vail, Thomas

2015-01-01

This work aimed to compare the diagnostic performance of a metal artifact suppression sequence (MAVRIC-SL) for imaging of hip arthroplasties (HA) at 1.5 and 3 Tesla (T) field strength. Eighteen patients (10 females; aged 27-74) with HA were examined at 3.0 and 1.5 T within 3 weeks. The sequence protocol included 3D-MAVRIC-SL PD (coronal), 3D-MAVRIC-SL STIR (axial), FSE T1, FSE PD and STIR sequences. Anatomical structures and pathological findings were assessed independently by two radiologists. Artifact extent and technical quality (image quality, fat saturation and geometric distortion) were also evaluated. Findings at 1.5 and 3.0 T were compared using a Wilcoxon signed rank test. While image quality was better at 1.5 T, visualization of anatomic structures and clinical abnormalities was not significantly different using the two field strengths (p > 0.05). Fat suppression and amount of artifacts were significantly better at 1.5 T (p < 0.01). Inter- and intra-reader agreement for different anatomic details, image quality and visualization of abnormalities ranged from k = 0.62 to k = 1.00. MAVRIC-SL at 1.5 T had a comparable diagnostic performance when compared MAVRIC-SL at 3.0 T; however, the higher field strength was associated with larger artifacts, limited image quality and worse fat saturation. (orig.)

Robust half-metallicity at the zincblende CrTe(0 0 1) surfaces and its interface with ZnTe(0 0 1)

International Nuclear Information System (INIS)

Ahmadian, F.; Abolhassani, M.R.; Hashemifar, S.J.; Elahi, M.

2010-01-01

All electron full potential calculations based on spin density functional theory are performed to study cubic zincblende (ZB) and hexagonal NiAs structures of bulk CrTe, free (0 0 1) surfaces of ZB CrTe, and interface of ZB CrTe with ZnTe(0 0 1). The ferromagnetic NiAs structure is reported to be about 0.26 eV more stable than the ferromagnetic ZB phase while ZB CrTe is found to be a half-metallic ferromagnet with a half-metallic gap of about 2.90 eV. Thermodynamic stability of CrTe(0 0 1) surfaces are studied in the framework of ab-initio thermodynamic. The obtained phase diagram evidences more stability of the Te terminated surface compared with the Cr termination. We discuss that both Te and Cr ideal terminations of CrTe(0 0 1) retain bulk-like half-metallic property but with a reduced half-metallic gap compared with bulk value. The structural, electronic, magnetic, and band alignment properties of the ZB CrTe/ZnTe(0 0 1) interface are computed and a rather large minority valence band offset of about 1.09 eV is observed in this heterojunction.

HEALTH INDICATORS IN SCHOOL: ASSESSMENT OF NUTRITIONAL STATUS AND MOTOR PERFORMANCE

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Andressa Ribeiro Contreira

2013-11-01

Full Text Available Objective: This study aimed to investigate the relationship among motor performance and nutritional status in students. Methods: Attended by 27 adolescents of both sexes, aged between 11-13 years (average 11.74 ± 0.70 years from a private school in Florianópolis/SC. The motor performance was assessed using the MABC-2. For assess the nutritional status was used the BMI calculus. Results: Among 27 participants, 6 had a risk / indicative of motor difficulties and 9 had overweight. The vast majority of participants had adequate height for age. There was negative significant statistically correlation, but moderate, among BMI and total performance in the MABC-2, indicating that as higher the BMI, worse is the motor performance. Conclusion: Based on these results and the literature, it is suggested that in addition to the identification of children with overweight and motor difficulties, programs targeted physical activity and motor interventions are implemented, especially in the school environment, aiming to maintain the health conditions.

Synthesis and electrochemical performance of long lifespan Li-rich Li1+x(Ni0.37Mn0.63)1−xO2 cathode materials for lithium-ion batteries

International Nuclear Information System (INIS)

Gao, Min; Lian, Fang; Liu, Hongquan; Tian, Cuijun; Ma, Leilei; Yang, Wangyue

2013-01-01

Highlights: ► Long lifespan Li 1+x (Ni 0.37 Mn 0.63 ) 1−x O 2 samples were obtained through adjusting the content of lithium. ► x = 0.123 and x = 0.111 can retain more than 80% of the initial discharge capacities at 0.5 C after 500 cycles. ► x = 0.086 shows high initial efficiency, high medium discharge voltage and good rate capability. ► The significant increase of charge-transfer resistance of the cells contributes to the capacity decay. -- Abstract: Li 1+x (Ni 0.37 Mn 0.63 ) 1−x O 2 (x = 0.123, 0.111, 0.086, 0.070, 0.031) cathode materials were synthesized via coprecipitation of carbonates and the samples with long lifespan for lithium ion batteries were obtained through adjusting the content of lithium. Their crystal structure and electrochemical performance were characterized by means of powder X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), inductive coupled plasma (ICP), galvanostatic charge/discharge test and electrochemical impedance spectrum (EIS). The XRD data show that the materials can be indexed as a single α-NaFeO 2 phase except the sample with x = 0.031. The FESEM results indicate that the primary particles size increase with an increase of x value and the secondary particles retain the spherical morphology. The as-prepared sample with x = 0.086 delivers the largest discharge capacity of 232.1 mAh g −1 and a high initial efficiency of 81.8% at 0.2 C in the potential range of 2.5–4.7 V. Moreover, the better cycle performances are obtained for samples with x = 0.123 and 0.111, and the capacity retentions are up to 89 and 81% of the first discharge capacity at 0.5 C after 500 cycles, respectively

Differences in eating behaviors and masticatory performances by gender and obesity status.

Science.gov (United States)

Park, Soojin; Shin, Weon-Sun

2015-01-01

This study aimed to determine whether there might be differences in masticatory performance and eating behaviors by gender and obesity status. Forty eight (24 males; 24 females) non-obese and pre-obese young adults were matched for age, gender, and dental health. Eating behaviors were assessed using the Three-Factor Eating Questionnaire (TFEQ), and chewing performance while eating 152g of boiled rice was measured using electromyography (EMG). Compared with non-obese participants, pre-obese participants had significantly higher levels of disinhibition according to the TFEQ (Pdifferent by gender but not by obesity status. Males had a greater bite size (Pobese) and chewing power (r=-0.581, Pobese and r=-0.446, Pobese) were negatively associated with disinhibition score. Results suggest that the effects of gender and, in part, obesity on eating responses may be explained as chewing performance. Therefore, gender-specific interventions and counseling aimed at slowing the rate of ingestion could be promising behavioral treatments for obese persons. Copyright © 2014 Elsevier Inc. All rights reserved.

Physical performance in relation to menopause status and physical activity.

Science.gov (United States)

Bondarev, Dmitriy; Laakkonen, Eija K; Finni, Taija; Kokko, Katja; Kujala, Urho M; Aukee, Pauliina; Kovanen, Vuokko; Sipilä, Sarianna

2018-05-21

The aim of this study was to examine differences in physical performance (muscle power, muscle strength, aerobic capacity, and walking speed) across menopausal stages and potential of leisure physical activity (PA) to modify the impact of menopause on physical performance. In this cross-sectional study, women aged 47 to 55 were randomly selected from the Finnish National Registry and categorized as premenopausal (n = 233), perimenopausal (n = 381), or postmenopausal (n = 299) based on serum concentrations of follicle-stimulating hormone and bleeding diary. Physical performance was measured by knee extension force, handgrip force, vertical jumping height, maximal walking speed, and 6-minute walking distance. PA level was assessed by self-report and categorized as low, moderate, or high. Multivariate linear regression modeling was used for data analysis. After including fat mass, height, PA, and education in the model, the postmenopausal women showed 12.0 N weaker (P women. There was no significant interaction between menopausal stage and PA on physical performance. The peri- and postmenopausal women with a high PA, however, showed better performance in the maximal knee extension strength and 6-minute walking test, and showed greater lower body muscle power than those with a low PA. Menopause status is associated with muscle strength and power, whereas the association between menopause status and mobility/walking is clearly weaker. A high leisure PA level provides more capacity to counteract the potential negative influence of menopausal factors on muscle function.This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0.

Improved electrochemical performance of Li1.2Mn0.54Ni0.13Co0.13O2 cathode material synthesized by citric acid assisted sol-gel method for lithium ion batteries

Science.gov (United States)

Li, Shiyou; Liang, Youwei; Lei, Dan; Xie, Yingchun; Ai, Ling; Xie, Jing

2018-03-01

A citric acid assisted sol-gel method is employed for synthesizing Li1.2Mn0.54Ni0.13Co0.13O2 used as a cathode material in lithium-ion batteries. Powder X-ray diffraction (XRD) and scanning electron microscopy (SEM) characterizations prove that materials have a typical a-NaFeO2 structure with primary nano-sized particles. Electrochemical performances have been investigated by charge-discharge test and results show that the synthesized product exhibits excellent electrochemical performance with a high initial discharge capacity of 253.5 mAh g-1 at 0.1 C and a preferable capacity retention of 84.8% after 50 cycles.

Effect of citric acid, avilamycin, and their combination on the performance, tibia ash, and immune status of broilers.

Science.gov (United States)

Chowdhury, R; Islam, K M S; Khan, M J; Karim, M R; Haque, M N; Khatun, M; Pesti, G M

2009-08-01

The aim of this study was to determine the effect of the supplementation of an organic acid (citric acid), antibiotic growth promoter (avilamycin), and their combination for a period of 35 d on the growth, feed efficiency, carcass yield, tibia ash, and immune status of broilers. One hundred sixty 1-d-old broiler chicks (Hubbard Classic) were randomly distributed into 4 groups with 4 replicate cages having 10 birds in each. A corn-soybean-based diet was used as the basal diet (control). The basal diet was supplemented with an organic acid (citric acid, 0.5%), an antibiotic growth promoter (avilamycin, 0.001%), and their combination in other groups. The highest BW was attained in citric acid-fed chicks (1,318 g), which was significantly (P 0.05). Total feed intake was higher in citric acid-fed chicks compared with antibiotic-supplemented chicks. The addition of citric acid improved feed conversion efficiency (g of weight gain/ kg of feed intake) significantly (P ash percentage significantly (P ash, and immune status of broilers. Therefore, citric acid might be a useful additive instead of antibiotic growth promoters such as avilamycin, considering performance and health status of broilers.

Analysis of the prognostic factors for low rectal cancer with the pT1-2NxM0 stage after abdominoperineal resection.

Science.gov (United States)

Zhang, Xing-mao; Ma, Chao; Sun, Da-yong; Wang, Zheng; Zhou, Zhi-xiang

2015-01-01

This study was designed to explore the factors influencing local recurrence and survival for low rectal cancer with pT1-2NxM0 stage after an abdominoperineal resection (APR). Data of 429 patients confirmed to have pT1-2NxM0 after APR were reviewed. The recurrence rate in patients with intraoperative perforation, less than 12 lymph nodes (LNs) harvested, T2 staging, and positive circumferential resection margin (CRM) was 25.1, 19.9, 9.5, and 26.1% compared with 6.9, 7.0, 0, and 5.8% in patients with no perforation, 12 or more LNs harvested, T1, and negative CRM. The 5-year survival rate in patients with age of at least 70, perforation, less than 12 LNs harvested, T2, and positive CRM was 71.1, 60.8, 58.8, 69.9, and 46.0%, but 73.4, 73.5, 73.8, 89.4, and 75.0% in patients with age less than 70, no perforation, 12 or more LNs harvested, T1, and negative CRM. Meanwhile, patients with N0, N1, and N2 had a survival rate of 90.7, 69.9, and 63.9%. Multivariate analysis showed that perforation (PCRM status (P=0.002) were associated with local recurrence, whereas age of the patients (P=0.023), N staging (PCRM status (P=0.004) were associated with survival. APR was affected by patients' age, operation performer, perforation, number of LNs harvested, T staging, N staging, differentiation, and CRM status. Perforation, number of LNs harvested, T staging, differentiation, and CRM status were independent factors for recurrence; meanwhile, age of the patients, N staging, differentiation, and CRM status were independent factors influencing survival.

Upper urinary tract stone disease in patients with poor performance status: active stone removal or conservative management?

Science.gov (United States)

Yamashita, Shimpei; Kohjimoto, Yasuo; Hirabayashi, Yasuo; Iguchi, Takashi; Iba, Akinori; Higuchi, Masatoshi; Koike, Hiroyuki; Wakamiya, Takahito; Nishizawa, Satoshi; Hara, Isao

2017-11-16

It remains controversial as to whether active stone removal should be performed in patients with poor performance status because of their short life expectancy and perioperative risks. Our objectives were to evaluate treatment outcomes of active stone removal in patients with poor performance status and to compare life prognosis with those managed conservatively. We retrospectively reviewed 74 patients with Eastern Cooperative Oncology Group performance status 3 or 4 treated for upper urinary tract calculi at our four hospitals between January 2009 and March 2016. Patients were classified into either surgical treatment group or conservative management group based on the presence of active stone removal. Stone-free rate and perioperative complications in surgical treatment group were reviewed. In addition, we compared overall survival and stone-specific survival between the two groups. Cox proportional hazards analysis was performed to investigate predictors of overall survival and stone-specific survival. Fifty-two patients (70.3%) underwent active stone removal (surgical treatment group) by extracorporeal shock wave lithotripsy (n = 6), ureteroscopy (n = 39), percutaneous nephrolithotomy (n = 6) or nephrectomy (n = 1). The overall stone-free rate was 78.8% and perioperative complication was observed in nine patients (17.3%). Conservative treatment was undergone by 22 patients (29.7%) (conservative management group). Two-year overall survival rates in surgical treatment and conservative management groups were 88.0% and 38.4%, respectively (p performance status could be performed safely and effectively. Compared to conservative management, surgical stone treatment achieved longer overall survival and stone-specific survival.

General Approach to Prepare 0.33Li₂MnO₃ · 0.67LiNi1/3Co1/3Mn1/3O₂ Hollow Microspheres for High Performance Lithium Ion Batteries.

Science.gov (United States)

Li, Jingfa; Xu, Wenjin; Zhang, Lei; Li, Min

2018-06-01

Li-excess manganese-based oxide layered structures, have drawn increasing interests as the promising cathodes to succeed the conventional LiCoO2 in lithium ion batteries (LIBs). It could deliver a higher energy density and output potential, as well as the nature of environment benign and low cost. Pristine Li-excess manganese-based oxides however suffer from poor rate capacity and voltage fading after cycling, and their inherent capacity limits of bulk size in performance. Micro-/Nanostructured electrode materials are considered to hold the key to overcome these thresholds. This paper reports a general approach to prepare 0.33Li2MnO3 · 0.67LiNi1/3Co1/3Mn1/3O2 microspheres with pores and void space, which benefits improving both the capacity and cyclability. The electrode made of hollow 0.33Li2MnO3 · 0.67LiNi1/3Co1/3Mn1/3O2 microspheres exhibits a 224 mAh g-1 discharge capacity over 200 cycles at 0.25 C rate, and 195 mAh g-1 at 5.0 C rate. These results indicated good perspective of hollow microspheres for practical battery applications.

Growth of langasite via Bridgman technique along [ 0 0 0 1], [ 2 1¯ 1¯ 0] and [ 0 1 1¯ 1] for piezoelectric applications

Science.gov (United States)

Uda, Satoshi; Inaba, Hitoshi; Harada, Jiro; Hoshikawa, Keigo

2004-10-01

2-inch langasite (La 3Ga 5SiO 14) single crystals were grown for the first time via a vertical Bridgman method, assisted by the accelerated crucible rotation technique (ACRT) along [ 0 0 0 1] ( Z-axis), [ 2 1¯ 1¯ 0] ( X-axis) and [ 0 1 1¯ 1] (54°-rotated Y-axis) for piezoelectric applications. Because of the possible liquid immiscibility, incongruency and segregation, secondary phases other than langasite are formed during growth. The mode of occurrence of these phases was closely related to the interface instability that was specific to the growth direction. The formation of inclusions consisting of lanthanum gallate (LaGaO 3), aligned parallel to ( 0 1 1¯ 0), was associated with the constitutional supercooling. The residual products during the terminal transient were the mixture of gallium oxide (Ga 2O 3) and lanthanum gallate (LaGaO 3) or the mixture of gallium oxide and lanthanum silicate (La 2Si 2O 7) reflecting the position of the initial melt, relative to the tie line connecting the langasite solid solution with gallium oxide in the system of La 2O 3-Ga 2O 3-SiO 2. The homogeneity of the grown crystal was evaluated by the distribution of SAW velocities of the devices fabricated on the ( 0 1 1¯ 0) wafer, as well as by the uniformity of d-spacing of 0 5 5¯ 5.

Primary central nervous system lymphoma: age and performance status are more important than treatment modality

International Nuclear Information System (INIS)

Corry, June; Smith, Jennifer G.; Wirth, Andrew; Quong, George; Liew, Kuen Hoe

1998-01-01

Purpose: To assess prognostic factors and treatment modalities of patients with primary central nervous system lymphoma (PCNSL) in terms of response rates, patterns of failure and overall survival. Methods and Materials: Sixty-two patients presenting with PCNSL between 1982 and 1994 at Peter MacCallum Cancer Institute with no evidence of human immunodeficiency virus infection were included in the study. Their median age was 60 years; World Health Organisation (WHO) performance status was ≥2 in 85%. All patients were planned to receive whole brain irradiation; 7 also received spinal irradiation. The median planned dose to the target volume was 50.4 Gy. Twenty patients were planned to receive chemotherapy as well. Patients were followed up to June 20, 1995, giving a median follow-up for 14 surviving patients of 5.4 years, range 0.3 to 10.2 years. Results: The clinical response rate to treatment was 77% [95% confidence interval (CI) 65 to 87%]. The estimated median overall survival was 20.6 months (CI 12.4 to 33.4 months). On univariate analysis male gender, age <60 years, WHO performance status ≤1, treatment to the target volume ≥45 Gy, and treatment with additional chemotherapy, were associated with a significantly better overall survival (p < 0.05). On multivariate analysis only age and performance status remained significant prognostic variables. Relapse involved the central nervous system or cerebrospinal fluid (CSF) in all patients with known sites of relapse except three who had ocular relapse only. There was a low incidence of relapse in the initial brain site (23% of known cases) and a high incidence (50%) of CSF/spinal cord relapse. Of 48 deaths, 15 were related to initial or subsequent treatment. Conclusions: Patient outcome is strongly influenced by age and performance status. Studies suggesting better survival for patients treated with chemoradiation may reflect patient selection rather than treatment variables. Optimal management remains to be

Association Between PAI-1 Activity Levels and t-PA Antigen with Glycemic Status in Prediabetic Population

Directory of Open Access Journals (Sweden)

Andi Fachruddin Benyamin

2016-11-01

Full Text Available Aim: to evaluate an association between fibrinolysis defect and glycemic status in prediabetic population by assessing the levels of t-PA antigen and PAI-1 activity. Methods: it was an observational study with cross-sectional approach. There were 72 subjects aged 30-50 years who had met the inclusion criteria. The diagnosis of diabetes mellitus (DM and glycemic index were determined based on the American Diabetes Association (ADA criteria. The PAI-1 and t-PA antigen levels were measured quantitatively using enzyme-linked immunosorbent assay (ELISA. Analysis between the levels of t-PA antigen and PAI-1 activity was performed using ANOVA. Results: the t-PA antigen level was significantly higher in subjects with impaired glucose tolerance (IGT and impaired fasting blood glucose (IFBG as well as subject with impaired fasting blood glucose (IFBG than those with normal glucose tolerance (NGT (p=0.047. The PAI-1 activity was significantly higher in subjects with IGT, IFBG and subjects with IFBG than NGT (p=0.024. There was a significant association between glycemic status in prediabetic subjects and PAI-1 activity (p=0.04. Conclusion: the level of t-PA antigen and PAI-1 activity were significantly higher in prediabetic subjects than those with NGT; and there was a significant association between glycemic status in prediabetic subjects and PAI-1 activity.

Treatment outcome in performance status 2 advanced NSCLC patients administered platinum-based combination chemotherapy

DEFF Research Database (Denmark)

Helbekkmo, Nina; Aasebø, Ulf; Sundstrøm, Stein H

2008-01-01

BACKGROUND: There is no consensus regarding chemotherapy to patients with advanced NSCLC (ANSCLC) and performance status (PS) 2. Using data from a national multicenter study comparing two third-generation carboplatin-based regimens in ANSCLC patients, we evaluated the outcome of PS 2 patients....... PATIENTS AND METHODS: The 123 PS 2 patients were compared to 309 PS 0/1 patients regarding survival, quality of life (QOL) and treatment toxicity. RESULTS: PS 2 patients had lower haemoglobin, lower global QOL and more pain, nausea/vomiting and dyspnea at inclusion. 68% of PS 2 patients received three...... chemotherapy courses vs. 85% in the PS 0/1 group (PPS 2 group, 4.5 vs. 8.9 months and 10% vs. 37% (PPS 2 patients needed blood transfusions (P=0.03) and hospitalization (PPS 2 patients had better relief of pain and dyspnea...

Synthesis of LiNi0.8Co0.1Mn0.1O2 cathode material by chloride co-precipitation method

Institute of Scientific and Technical Information of China (English)

李灵均; 李新海; 王志兴; 伍凌; 郑俊超; 李金辉

2010-01-01

LiNi0.8Co0.1Mn0.1O2 was prepared by a chloride co-precipitation method and characterized by thermogravimetric analysis, X-ray diffractometry with Rietveld refinement,electron scanning microscopy and electrochemical measurements.Effects of lithium ion content and sintering temperature on physical and electrochemical performance of LiNi0.8Co0.1Mn0.1O2 were also investigated. The results show that the sample synthesized at 750℃with 105%lithium content has fine particle sizes around 200 nm and homogenous sizes distribution.The initial discharge capacity for the powder is 184 mA·h/g between 2.7 and 4.3 V at 0.1C and room temperature.

Status of the NA62 liquid krypton electromagnetic calorimeter Level 0 trigger processor

CERN Document Server

Bonaiuto, V; Fucci, A; Paoluzzi, G; Salamon, A; Salina, G; Santovetti, E; Sargeni, F; Venditti, S

2013-01-01

The NA62 experiment at the CERN SPS aims to measure the Branching Ratio of the very rare kaon decay K(+)→π(+)νbar nu collecting O(100) events with a 10% background in two years of data taking. To reject the K(+)→π(+)π(0) background the NA48 liquid krypton calorimeter will be used in the 1-10 mrad angular region. The status of the Liquid Krypton Electromagnetic Calorimeter Level 0 Trigger is presented.

Variations in Oncologist Recommendations for Chemotherapy for Stage IV Lung Cancer: What Is the Role of Performance Status?

Science.gov (United States)

Tisnado, Diana; Malin, Jennifer; Kahn, Katherine; Landrum, Mary Beth; Fletcher, Robert; Klabunde, Carrie; Clauser, Steven; Rogers, Selwyn O; Keating, Nancy L

2016-07-01

Chemotherapy prolongs survival in patients with advanced non-small-cell lung cancer. However, few studies have included patients with poor performance status. This study examined rates of oncologists' recommendations for chemotherapy by patient performance status and symptoms and how physician characteristics influence chemotherapy recommendations. We surveyed medical oncologists involved in the care of a population-based cohort of patients with lung cancer from the CanCORS (Cancer Care Outcomes Research and Surveillance) study. Physicians were queried about their likelihood to recommend chemotherapy to patients with stage IV lung cancer with varying performance status (Eastern Cooperative Oncology Group performance status 0 [good] v 3 [poor]) and presence or absence of tumor-related pain. Repeated measures logistic regression was used to estimate the independent associations of patients' performance status and symptoms and physicians' demographic and practice characteristics with chemotherapy recommendations. Nearly all physicians (adjusted rate, 97% to 99%) recommended chemotherapy for patients with good performance status, and approximately half (adjusted rate, 38% to 53%) recommended chemotherapy for patients with poor performance status (P factors, physician and practice characteristics were less strongly associated with chemotherapy recommendations in adjusted analyses. Strong consensus among oncologists exists for chemotherapy in patients with advanced non-small-cell lung cancer and good performance status. However, the relatively high rate of chemotherapy recommendations for patients with poor performance status despite the unfavorable risk-benefit profile highlights the need for ongoing work to define high-value care in oncology and to implement and evaluate strategies to align incentives for such care. Copyright © 2016 by American Society of Clinical Oncology.

High-Performance, 0.6-eV, GA0.32In0.68As/In0.32P0.68 Thermophotovoltaic Converters and Monolithically Interconnected Modules

International Nuclear Information System (INIS)

Duda, A.; Murray, C.S.

1998-01-01

Recent progress in the development of high-performance, 0.6-eV Ga0.32In0.68As/InAs0.32P0.68 thermophotovoltaic (TPV) converters and monolithically interconnected modules (MIMs) is described. The converter structure design is based on using a lattice-matched InAs0.32P0.68/Ga0.32In0.68As/InAs0.32P0.68 double-heterostructure (DH) device, which is grown lattice-mismatched on an InP substrate, with an intervening compositionally step-graded region of InAsyP1-y. The Ga0.32In0.68As alloy has a room-temperature band gap of 0.6 eV and contains a p/n junction. The InAs0.32P0.68 layers have a room-temperature band gap of 0.96 eV and serve as passivation/confinement layers for the Ga0.32In0.68As p/n junction. InAsyP1-y step grades have yielded DH converters with superior electronic quality and performance characteristics. Details of the microstructure of the converters are presented. Converters prepared for this work were grown by atmospheric-pressure metalorganic vapor-phase epitaxy (APMOVPE) and were processed using a combination of photolithography, wet-chemical etching, and conventional metal and insulator deposition techniques. Excellent performance characteristics have been demonstrated for the 0.6-eV TPV converters. Additionally, the implementation of MIM technology in these converters has been highly successful

Upper gastrointestinal symptoms in patients with advanced cancer: relationship to nutritional and performance status.

Science.gov (United States)

Bovio, G; Montagna, G; Bariani, C; Baiardi, P

2009-10-01

The goals of the study were to determine the relationship of upper gastrointestinal symptoms with nutritional status and to assess their association with performance status in patients with advanced cancer. We studied 143 patients (50 F, 93 M, mean age 68 +/- 11 years, mean body mass index 22.39 +/- 4.3 kg/m(2)). Assessed symptoms were the following: anorexia, nausea, vomiting, dysphagia for solids, dysphagia for liquids, xerostomia, hypogeusia, dysgeusia, hiccup and chewing disturbances. We determined anthropometric parameters, daily energy intake and serum albumin, prealbumin and transferrin. The most common upper gastrointestinal symptoms were xerostomia (73%), anorexia (49%) and chewing disturbances (40%). Fifty-four percent of patients had weight loss greater than 10%. Seventy-three patients (51%) had daily energy intake lower than their resting energy expenditure. Mean serum prealbumin, albumin and transferrin were below normal range. Mean Eastern Cooperative Oncology Group performance status scale was 3.1 +/- 0.49. Symptoms were often strongly correlated, and usually, patients experienced at least three upper gastrointestinal symptoms at the same time. Anorexia, nausea and vomiting were the symptoms mostly correlated with other symptoms. A correlation was found between vomiting and hiccup. Energy intake (EI) was the nutritional parameter mostly affected by upper gastrointestinal symptoms; moreover, EI is the most predictive factor of upper gastrointestinal symptoms, particularly xerostomia, anorexia and dysphagia for solids. Upper gastrointestinal symptoms are linked to nutritional parameters: In particular, energy intake represents the most predictive variable of symptom occurrence. The performance status is not affected by upper gastrointestinal symptoms. A rigorous nutritional assessment and the managing of upper gastrointestinal symptoms are crucial in patients with advanced cancer.

Oxidation of graphene on Ru(0 0 0 1) studied by scanning tunneling microscopy

International Nuclear Information System (INIS)

Liao, Q.; Zhang, H.J.; Wu, K.; Li, H.Y.; Bao, S.N.; He, P.

2010-01-01

The oxidation of graphene layer on Ru(0 0 0 1) has been investigated by means of scanning tunneling microscopy. Graphene overlayer can be formed by decomposing ethyne on Ru(0 0 0 1) at a temperature of about 1000 K. The lattice mismatch between the graphene overlayer and the substrate causes a moire pattern with a superstructure in a periodicity of about 30 A. The oxidation of graphene/Ru(0 0 0 1) was performed by exposure the sample to O 2 gas at 823 K. The results showed that, at the initial stage, the oxygen intercalation between the graphene and the Ru(0 0 0 1) substrate takes place at step edges, and extends on the lower steps. The oxygen intercalation decouples the graphene layer from the Ru(0 0 0 1) substrate. More oxygen intercalation yields wrinkled bumps on the graphene surface. The oxidation of graphene, or the removal of carbon atoms can be attributed to a process of the combination of the carbon atoms with atomic oxygen to form volatile reaction products. Finally, the Ru(0 0 0 1)-(2 x 1)O phase was observed after the graphene layer is fully removed by oxidation.

Improved iodine status is associated with improved mental performance of schoolchildren in Benin.

Science.gov (United States)

van den Briel, T; West, C E; Bleichrodt, N; van de Vijver, F J; Ategbo, E A; Hautvast, J G

2000-11-01

An adequate iodine supply in utero and shortly after birth is known to be crucial to an individual's physical and mental development. The question of whether iodine supplementation later in life can exert a favorable influence on the mental performance of iodine-deficient populations was addressed in various studies, but with contradictory results. The aim of this study was to examine the effect of an improvement in iodine status on mental and psychomotor performance of schoolchildren (7-11 y) who were moderately to severely iodine deficient. The study, which was originally planned as a double-blind, randomized, placebo-controlled intervention, was carried out in an iodine-deficient population of schoolchildren (n = 196) in northern Benin. As the population began to have access to iodized salt during the 1-y intervention period, the study population was split post hoc-on the basis of urinary iodine concentrations-into a group with improved iodine status and a group with unchanged iodine status. Changes in mental and psychomotor performance over the intervention period were compared. Children with increased urinary iodine concentrations had a significantly greater increase in performance on the combination of mental tests than did the group with no change in urinary iodine concentrations. An improvement in iodine status, rather than iodine status itself, determined mental performance in this population, which was initially iodine deficient. These findings suggest a "catch-up" effect in terms of mental performance.

Removal of Endobronchial Malignant Mass by Cryotherapy Improved Performance Status to Receive Chemotherapy

Science.gov (United States)

Hsieh, Meng-Heng; Wang, Tsai-Yu; Yu, Chih-Teng; Chou, Chun-Liang; Lin, Shu-Min; Kuo, Chih-Hsi; Chung, Fu-Tsai

2014-01-01

Although malignant endobronchial mass (MEM) has poor prognosis, cryotherapy is reportedly a palliative treatment. Clinical data on postcryotherapy MEM patients in a university-affiliated hospital between 2007 and 2011 were evaluated. Survival curve with or without postcryotherapy chemotherapy and performance status (PS) improvement of these subjects were analyzed using the Kaplan-Meier method. There were 59 patients (42 males), with median age of 64 years (range, 51–76, and median performance status of 2 (interquartile range [IQR], 2-3). Postcryotherapy complications included minor bleeding (n = 12) and need for multiple procedures (n = 10), while outcomes were relief of symptoms (n = 51), improved PS (n = 45), and ability to receive chemotherapy (n = 40). The survival of patients with chemotherapy postcryotherapy was longer than that of patients without such chemotherapy (median, 534 versus 106 days; log-rank test, P = 0.007; hazard ratio, 0.25; 95% confidence interval, 0.10–0.69). The survival of patients with PS improvement postcryotherapy was longer than that of patients without PS improvement (median, 406 versus 106 days; log-rank test, P = 0.02; hazard ratio, 0.28; 95% confidence interval, 0.10–0.81). Cryotherapy is a feasible treatment for MEM. With better PS after cryotherapy, further chemotherapy becomes possible for patients to improve survival when MEM caused dyspnea and poor PS. PMID:25383370

Efficient photocatalytic reductive dechlorination of 4-chlorophenol to phenol on {0 0 1}/{1 0 1} facets co-exposed TiO_2 nanocrystals

International Nuclear Information System (INIS)

Jiang, Guodong; Wei, Meng; Yuan, Songdong; Chang, Qing

2016-01-01

Graphical abstract: - Highlights: • 4-Chlorophenol is dechlorinated over {0 0 1}/{1 0 1} co-exposed TiO_2 nanocrystals. • Photo-electrons are accumulated on {1 0 1} facets due to surface heterojunction. • Fluorine will trap photoelectrons to depress the dechlorination performance. • Sufficient isopropanol promotes the dechlorination activity and selectivity. - Abstract: 4-chlorophenol could be efficiently photoreductively dechlorinated over anatase TiO_2 nanocrystals with co-exposed {0 0 1} and {1 0 1} facets, which were synthesized and further characterized by scanning electron microscope (SEM), transmission electron microscope (TEM), X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS). Although fluorine could adsorb on {0 0 1} facets to decrease their surface energy, enabling TiO_2 to expose high energy {0 0 1} facets, the surface bonded fluorine might depress the photoreductive dechlorination efficiency of 4-chlorophenol, attributed to the electron trapping role of surface ≡Ti−F groups. Due to the formation of a surface heterojunction between {1 0 1} and {0 0 1} facets in a single TiO_2 nanocrystal, electrons and holes were spontaneously self-separated and selectively migrate to {1 0 1} and {0 0 1} facets, respectively. Electron trapping experiments demonstrated that photogenerated electrons are the responsible for the reductive dechlorinaton of 4-chlorophenol to phenol. To avoid the oxidative degradation of 4-chlorophenol by holes and ensure sufficient electrons to reductively dechlorinate the substrate, moderate scavengers were required in the reaction system and dissolved oxygen, which might deplete electron on TiO_2, also should be removed. With the optimal scavengers, the conversion efficiency of 4-chlorophenol (4-CP) achieved 97.5% and the selectivity for phenol was 92.5%, which were much higher than that of commercial TiO_2 P25.

Non-weight-bearing status compromises the functional level up to 1 yr after hip fracture surgery

DEFF Research Database (Denmark)

Ariza-Vega, Patrocinio; Jiménez-Moleón, José Juan; Kristensen, Morten Tange

2014-01-01

, age, health status, and cognitive impairment of the patient were associated negatively with the 1-yr functional outcome (P ≤ 0.03). Prefracture functional level and non-WB status were the strongest determinants of functional level (β = 0.599 and -0.204, respectively; P ... after surgery, in addition to prefracture function, cognitive status, health status, age and fracture type, was found to be an independent predictor of the 1-yr functional outcome in hip fracture patients....

Magnetisation and AC susceptibility studies of La1-xSrxFe0.8Cr0.2O3-δ (0.01.0) perovskites

International Nuclear Information System (INIS)

Ferreira, L.P.; Cruz, M.M.; Ramos, T.; Sa, M.A.; Carvalho, M.D.; Godinho, M.

2007-01-01

Magnetisation and AC magnetic susceptibility measurements have been performed in the perovskite-type compounds La 1-x Sr x Fe 0.8 Cr 0.2 O 3-δ (x=0.2, 0.4, 0.6 and 0.8). All compounds show an overall antiferromagnetic behaviour mainly attributed to predominant Fe 3+ -O-Fe 3+ interactions. For 0.2 ord . The coexistence of AFM and FM interactions leads to reentrant magnetic behaviour for the x=0.4 compound and to spin-glass like behaviour for x=0.8. Between x=0.6 and 0.8, the similar magnetic moments found in the paramagnetic region indicate that the Fe/Cr valences do not change significantly, pointing towards an increased role for oxygen vacancy formation in the charge compensation mechanism

The Majorana Demonstrator for 0νββ: Current Status and Future Plans

Energy Technology Data Exchange (ETDEWEB)

Green, Matthew P. [ORNL; Avignone, F. T. [University of South Carolina/Oak Ridge National Laboratory (ORNL); Bertrand, Jr, Fred E [ORNL; Galindo-Uribarri, Alfredo [ORNL; Radford, David C [ORNL; Romero-Romero, Elisa [ORNL; Varner, Jr, Robert L [ORNL; White, Brandon R [ORNL; Wilkerson, J. F. [UNC/Triangle Univ. Nucl. Lab, Durham, NC/ORNL; Yu, Chang-Hong [ORNL

2015-01-01

The Majorana Demonstrator will search for neutrinoless-double-beta decay (0νββ) in 76Ge, while establishing the feasibility of a future tonne-scale germanium-based 0νββ experiment, and performing searches for new physics beyond the Standard Model. The experiment, currently under construction at the Sanford Underground Research Facility in Lead, SD, will consist of a pair of modular high-purity germanium detector arrays housed inside of a compact copper, lead, and polyethylene shield. Through a combination of strict materials qualifications and assay, low-background design, and powerful background rejection techniques, the Demonstrator aims to achieve a background rate in the 0νββ region of interest (ROI) of no more than 3cnts/(ROI-t-y). The current status of the Demonstrator is discussed, as are plans for its completion.

Direct and indirect relationships of physical fitness, weight status, and learning duration to academic performance in Japanese schoolchildren.

Science.gov (United States)

Ishihara, Toru; Morita, Noriteru; Nakajima, Toshihiro; Okita, Koichi; Yamatsu, Koji; Sagawa, Masato

2018-03-01

The purpose of this study was to determine, using structural equation modelling (SEM), the direct and indirect influence of daily behaviours (i.e. exercise/learning durations), weight status, and physical fitness on academic performance among seventh-grade schoolchildren, after controlling for socioeconomic status. We analysed cross-sectional data from 274 schoolchildren (159 males and 115 females; 12-13 years old). Academic performance was assessed using the total grade points in eight academic subjects. Physical fitness was evaluated using the total score of eight physical fitness tests and weight status using body mass index. The daily behaviours and socioeconomic status were assessed by the questionnaire. The SEM showed an adequate fit to the data (χ 2  = 0.684, p = .710, RMSEA = .000). Physical fitness and learning durations had direct effects on academic performance (β = .301, p academic performance via physical fitness. These findings suggest that, independent of socioeconomic status and learning durations, exercise habits and maintaining healthy weight status may indirectly contribute to academic success via better physical fitness in children.

Effects of polymannuronate on performance, antioxidant capacity, immune status, cecal microflora, and volatile fatty acids in broiler chickens.

Science.gov (United States)

Zhu, Wenhui; Li, Defa; Wang, Jianhong; Wu, Hui; Xia, Xuan; Bi, Wanghua; Guan, Huashi; Zhang, Liying

2015-03-01

The aim of this study was to assess the effects of purified polymannuronate (PM) obtained from marine brown algae on the performance, antioxidant capacity, immune status, and cecal fermentation profile of broiler chickens. In a 42 d experiment, 540 (average BW 43.77±1.29 g) 1-d-old Arbor Acres male broilers were randomly divided into 5 treatments with 6 replicates of 18 chicks and fed a corn and soybean meal (SBM)-based diet supplemented with 0, 1, 2, 3, or 4 g/kg polymannuronate. Adding polymannuronate to the broiler chickens' diets resulted in a significantly increased ADG and improved feed conversion compared with the control treatment. From d 1 to 42, the ADG of broilers fed 1, 2, 3, or 4 g/kg of polymannuronate was increased by 2.58, 4.33, 4.20, and 3.47%, respectively. Furthermore, parameters related to immune status, antioxidant capacity, and composition of the cecal microflora in broiler chickens fed the polymannuronate-containing diets were altered compared with broiler chickens fed a diet without polymannuronate. Supplementation with polymannuronate significantly increased the concentrations of lactic acid and acetic acid in the cecum compared with the control group. The results indicate that polymannuronate has the potential to improve broiler chicken immune status, antioxidant capacity, and performance. © 2015 Poultry Science Association Inc.

Nanoscratching of silver (1 0 0) with a diamond tip

CERN Document Server

Mulliah, D; Kenny, S D; Smith, R

2003-01-01

Parallel molecular dynamics simulations of nanoindentation followed by nanoscratching were conducted on an fcc silver (1 0 0) surface using a diamond indenter. The simulations were performed using three different orientations of the indenter. For each orientation, simulations were performed for an indentation depth of 5 A and scratching length of 210 A. The damage on the substrate is investigated and the coefficient of friction calculated for all the three cases. The results show few sub-surface defects underneath the scratch groove, pile-up around the groove which is orientation dependent and that the friction coefficient varies from approx 0.37 to approx 0.57 depending on the tip orientation.

Solvothermal fabrication of TiO2/sepiolite composite gel with exposed {0 0 1} and {1 0 1} facets and its enhanced photocatalytic activity

Science.gov (United States)

Liu, Ruirui; Ji, Zhijiang; Wang, Jing; Zhang, Jinjun

2018-05-01

A novel TiO2/sepiolite composite gel (TiSG) was fabricated in the presence of cetyltrimethylammonium bromide (CTAB) through a simple solvothermal reaction in an acetic acid-water solvent. A homogeneous anchoring of TiO2 nanoparticles with exposed {0 0 1} and {1 0 1} facets on sepiolite nanofibers was achieved. CTAB content, solvothermal temperature/time, and HAc content play crucial roles in the morphological and facet formation of TiSG. A possible mechanism for the formation of TiSG was further proposed. CTAB as capping/shape-controlling agent can strongly bind to the more reactive (0 0 1) facet of TiO2 and then mitigate the thermodynamically favored (0 0 1) plane growth. Eventually, the truncated octahedral TiO2 was obtained by controlling the growth rates in 〈0 0 1〉 and 〈1 0 1〉 directions. Sepiolite as a cross-linking agent provides sufficient crosslinking sites for TiO2 to induce three-dimensional (3D) network formation, thereby generating the composite gel. The synthesized TiSG samples were then used as photocatalysts, which exhibited increased methyl orange removal under UV-vis light (350-780 nm) by the synergistic effect of adsorption and in-situ photocatalytic degradation as compared to P25 and bare TiO2. The excellent photocatalytic performance of TiSG was mainly ascribed to the formations of 3D gel structure and surface heterojunctions between (0 0 1) and (1 0 1) facets.

The MAJORANA DEMONSTRATOR for 0νββ: Current Status and Future Plans

Science.gov (United States)

Green, M. P.; Abgrall, N.; Aguayo, E.; Avignone, F. T.; Barabash, A. S.; Bertrand, F. E.; Boswell, M.; Brudanin, V.; Busch, M.; Byram, D.; Caldwell, A. S.; Chan, Y.-D.; Christofferson, C. D.; Combs, D. C.; Cuesta, C.; Detwiler, J. A.; Doe, P. J.; Efremenko, Yu.; Egorov, V.; Ejiri, H.; Elliott, S. R.; Fast, J. E.; Finnerty, P.; Fraenkle, F. M.; Galindo-Uribarri, A.; Giovanetti, G. K.; Goett, J.; Gruszko, J.; Guiseppe, V. E.; Gusev, K.; Hallin, A. L.; Hazama, R.; Hegai, A.; Henning, R.; Hoppe, E. W.; Howard, S.; Howe, M. A.; Keeter, K. J.; Kidd, M. F.; Kochetov, O.; Konovalov, S. I.; Kouzes, R. T.; LaFerriere, B. D.; Leon, J.; Leviner, L. E.; Loach, J. C.; MacMullin, J.; MacMullin, S.; Martin, R. D.; Meijer, S.; Mertens, S.; Nomachi, M.; Orrell, J. L.; O'Shaughnessy, C.; Overman, N. R.; Phillips, D. G.; Poon, A. W. P.; Pushkin, K.; Radford, D. C.; Rager, J.; Rielage, K.; Robertson, R. G. H.; Romero-Romero, E.; Ronquest, M. C.; Schubert, A. G.; Shanks, B.; Shima, T.; Shirchenko, M.; Snavely, K. J.; Snyder, N.; Suriano, A. M.; Thompson, J.; Timkin, V.; Tornow, W.; Trimble, J. E.; Varner, R. L.; Vasilyev, S.; Vetter, K.; Vorren, K.; White, B. R.; Wilkerson, J. F.; Wiseman, C.; Xu, W.; Yakushev, E.; Young, A. R.; Yu, C.-H.; Yumatov, V.

The MAJORANA DEMONSTRATOR will search for neutrinoless-double-beta decay (0νββ) in 76Ge, while establishing the feasibility of a future tonne-scale germanium-based 0νββ experiment, and performing searches for new physics beyond the Standard Model. The experiment, currently under construction at the Sanford Underground Research Facility in Lead, SD, will consist of a pair of modular high-purity germanium detector arrays housed inside of a compact copper, lead, and polyethylene shield. Through a combination of strict materials qualifications and assay, low-background design, and powerful background rejection techniques, the Demonstrator aims to achieve a background rate in the 0νββ region of interest (ROI) of no more than 3 counts in the 0νββ-decay ROI per tonne of target isotope per year (cnts/(ROI-t-y)). The current status of the Demonstrator is discussed, as are plans for its completion.

RDM Lifetime measurement in "1"0"0Ru

International Nuclear Information System (INIS)

Gupta, C.K.; Rohilla, Aman; Chamoli, S.K.; Singh, R.P.; Murlithar, S.; Chakraborty, S.; Sharma, H.P.; Rai, S.; Kumar, A.; Govil, I.M.

2016-01-01

The energy level sequences of nuclei in A ∼ 100 mass region show an interesting interplay between single-particle and collective degrees of freedom. The measured transition probabilities in "9"8Ru suggest that the nucleus has both single-particle and vibrational character. To see how the nature of this nucleus changes with addition of 2 neutrons, we performed RDM lifetime measurement in yrast sequence of "1"0"0Ru at Inter University Accelerator Center (IUAC), New Delhi

Efficient photocatalytic reductive dechlorination of 4-chlorophenol to phenol on {0 0 1}/{1 0 1} facets co-exposed TiO{sub 2} nanocrystals

Energy Technology Data Exchange (ETDEWEB)

Jiang, Guodong; Wei, Meng; Yuan, Songdong [College of Chemistry and chemical engineering, Hubei Collaborative Innovation Center for High Efficient Utilization of Solar Energy, Hubei University of Technology, Wuhan 430068 (China); Chang, Qing, E-mail: changqinghust@163.com [Key Laboratory of Catalysis and Materials Science of the State Ethnic Affairs Commission and Ministry of Education, College of Resources and Environmental Science, South-Central University for Nationalities, Wuhan 430074 (China)

2016-01-30

Graphical abstract: - Highlights: • 4-Chlorophenol is dechlorinated over {0 0 1}/{1 0 1} co-exposed TiO{sub 2} nanocrystals. • Photo-electrons are accumulated on {1 0 1} facets due to surface heterojunction. • Fluorine will trap photoelectrons to depress the dechlorination performance. • Sufficient isopropanol promotes the dechlorination activity and selectivity. - Abstract: 4-chlorophenol could be efficiently photoreductively dechlorinated over anatase TiO{sub 2} nanocrystals with co-exposed {0 0 1} and {1 0 1} facets, which were synthesized and further characterized by scanning electron microscope (SEM), transmission electron microscope (TEM), X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS). Although fluorine could adsorb on {0 0 1} facets to decrease their surface energy, enabling TiO{sub 2} to expose high energy {0 0 1} facets, the surface bonded fluorine might depress the photoreductive dechlorination efficiency of 4-chlorophenol, attributed to the electron trapping role of surface ≡Ti−F groups. Due to the formation of a surface heterojunction between {1 0 1} and {0 0 1} facets in a single TiO{sub 2} nanocrystal, electrons and holes were spontaneously self-separated and selectively migrate to {1 0 1} and {0 0 1} facets, respectively. Electron trapping experiments demonstrated that photogenerated electrons are the responsible for the reductive dechlorinaton of 4-chlorophenol to phenol. To avoid the oxidative degradation of 4-chlorophenol by holes and ensure sufficient electrons to reductively dechlorinate the substrate, moderate scavengers were required in the reaction system and dissolved oxygen, which might deplete electron on TiO{sub 2}, also should be removed. With the optimal scavengers, the conversion efficiency of 4-chlorophenol (4-CP) achieved 97.5% and the selectivity for phenol was 92.5%, which were much higher than that of commercial TiO{sub 2} P25.

Crystal structure and magnetic properties of La2−x(Sr0.5Ca0.5)1+xMn2O7 (x=0.6, 0.8 and 1.0) Ruddlesden–Popper manganites

International Nuclear Information System (INIS)

Raju, K.; Song, M.S.; Lee, J.Y.

2014-01-01

Double layer perovskite (Ruddlesden–Popper) manganites with the nominal composition of La 2−x (Sr 0.5 Ca 0.5 ) 1+x Mn 2 O 7 (x=0.6, 0.8 and 1.0) were synthesized via a solid state reaction route. X-ray and neutron diffraction were performed at room temperature and the crystal structure was refined using the Rietveld method based on the space group, I4/mmm. The temperature variation of the susceptibility revealed a spin glass transition at 28 K for x=0.6, a charge ordering transition at 245 K and a Neel transition at 170 K for x=1.0. - Highlights: • Lanthanum based double layered manganites were prepared by doping with the same amounts of Sr and Ca. • X-ray and neutron diffraction were performed and the crystal structure was refined using the Rietveld method. • Different magnetic transitions were observed depending upon the doping concentration. • Qualitative explanation for the various observed phenomena was given

Epitaxial growth of Co(0 0 0 1)hcp/Fe(1 1 0)bcc magnetic bi-layer films on SrTiO3(1 1 1) substrates

International Nuclear Information System (INIS)

Ohtake, Mitsuru; Shikada, Kouhei; Kirino, Fumiyoshi; Futamoto, Masaaki

2008-01-01

Co(0 0 0 1) hcp /Fe(1 1 0) bcc epitaxial magnetic bi-layer films were successfully prepared on SrTiO 3 (1 1 1) substrates. The crystallographic properties of Co/Fe epitaxial magnetic bi-layer films were investigated. Fe(1 1 0) bcc soft magnetic layer grew epitaxially on SrTiO 3 (1 1 1) substrate with two type variants, Nishiyama-Wasserman and Kurdjumov-Sachs relationships. An hcp-Co single-crystal layer is obtained on Ru(0 0 0 1) hcp interlayer, while hcp-Co layer formed on Au(1 1 1) fcc or Ag(1 1 1) fcc interlayer is strained and may involve fcc-Co phase. It has been shown possible to prepare Co/Fe epitaxial magnetic bi-layer films which can be usable for patterned media application

Electrochemical performance of Ni0.8Cu0.2/Ce0.8Gd0.2O1.9 cermet anodes with functionally graded structures for intermediate-temperature solid oxide fuel cell fueled with syngas

Science.gov (United States)

Miyake, Michihiro; Iwami, Makoto; Takeuchi, Mizue; Nishimoto, Shunsuke; Kameshima, Yoshikazu

2018-06-01

The electrochemical performance of layered Ni0.8Cu0.2/Ce0.8Gd0.2O1.9 (GDC) cermet anodes is investigated for intermediate-temperature solid oxide fuel cells (IT-SOFCs) at 600 °C using humidified (3% H2O) model syngas with a molar ratio of H2/CO = 3/2 as the fuel. From the results obtained, the electrochemical performance of the functionally graded multi-layered anodes is found to be superior to the mono-layered anodes. The test cell with a bi-layered anode consisting of 100 mass% Ni0.8Cu0.2/0 mass% GDC (10M/0E) and 70 mass% Ni0.8Cu0.2/30 mass% GDC (7M/3E) exhibits high power density. The test cell with a tri-layered anode consisting of 10M/0E, 7M/3E, and 50 mass% Ni0.8Cu0.2/50 mass% GDC (5M/5E) exhibits an even higher power density, suggesting that 10M/0E and 5M/5E layers contribute to the current collecting part and active part, respectively.

Indico 1.0

CERN Document Server

Lopez, J B Gonzalez; Baron, T; Ferreira, P; Kolobara, B; Pugh, M A; Resco, A; Trzaskoma, J P

2014-01-01

Indico has evolved into the main event organization software, room booking tool and collaboration hub for CERN. The growth in its usage has only accelerated during the past 9 years, and today Indico holds more that 215,000 events and 1,100,000 files. The growth was also substantial in terms of functionalities and improvements. In the last year alone, Indico has matured considerably in 3 key areas: enhanced usability, optimized performance and additional features, especially those related to meeting collaboration. Along the course of 2012, much activity has centred around consolidating all this effort and investment into 'version 1.0', recently released in 2013.Version 1.0 brings along new features, such as the Microsoft Exchange calendar synchronization for participants, many new and clean interfaces (badges and poster generation, list of contributions, abstracts, etc) and so forth. But most importantly, it brings a message: Indico is now stable, consolidated and mature after more than 10 years of non-stop de...

Coping style and performance status in a group of oncological inpatients

Directory of Open Access Journals (Sweden)

Cecilia Chau Pérez-Aranibar

2002-06-01

Full Text Available The associations between coping styles, measured by COPE Test, dispositional version (Carver,Scheier and Weintraub, 1989, and Health Status inferred through a performance status, measured by Karnofsky's Index of Behavioral Performance are examined. The study focuses upon 28 oncological in patients. Positive moderate Pearson's correlations were found between these two variables in this correlational-descriptive study. These were interpreted in the following sense: the larger use of the style, the less health status among the scales suppression of competent activities, procrastination of coping, instrumental social support, focusing and releasing of emotions and behavioral disengagement. The active coping scale presented a negative correlationwith regard to Performance Status as a health measure.

Adolescent Weight Status and Self-Reported School Performance in South Korea

Directory of Open Access Journals (Sweden)

Young Kyung Do

2011-01-01

Full Text Available Using a nationally representative sample of 142 783 middle school (13–15 years old and high school (16–18 years old students in South Korea, this study examined whether (1 overweight and obesity are more likely to be associated with lower self-reported school performance; (2 overweight and obese students are more likely to enrol in a vocational high school as opposed to a general high school; (3 the association between obesity and poorer self-reported school performance is mediated through body image stress and health status. We found that excess weight was negatively associated with self-reported school performance among middle and general high school students, and that obese students had a higher probability of being enrolled in a vocational over a general high school. We did not find strong evidence on the mediating role of body image stress and health status.

Imaging performance of a dedicated radiation transparent RF coil on a 1.0 Tesla inline MRI-linac.

Science.gov (United States)

Liney, Gary P; Dong, Bin; Weber, Ewald; Rai, Robba; Destruel, Aurelien; Garcia-Alvarez, Roberto; Manton, David; Jelen, Urszula; Zhang, Kevin; Barton, Michael; Keall, Paul J; Crozier, Stuart

2018-05-25

This work describes the first imaging studies on a 1.0 Tesla inline MRI-Linac using a dedicated transmit/receive RF body coil that has been designed to be completely radio transparent and provide optimum imaging performance over a large patient opening. Methods: A series of experiments was performed on the MRI-Linac to investigate the performance and imaging characteristics of a new dedicated volumetric RF coil: (1) numerical electromagnetic simulations were used to measure transmit efficiency in two patient positions; (2) image quality metrics of signal-to-noise ratio (SNR), ghosting and uniformity were assessed in a large diameter phantom with no radiation beam; (3) radiation induced effects were investigated in both the raw data (k-space) and image sequences acquired with simultaneous irradiation; (4) radiation dose was measured with and without image acquisition; (5) RF heating was studied using an MR-compatible fluoroptic thermometer and; (6) the in vivo image quality and versatility of the coil was demonstrated in normal healthy subjects for both supine and standing positions. Results: Daily phantom measurements demonstrated excellent imaging performance with stable SNR over a period of 3 months (42.6 ± 0.9). Simultaneous irradiation produced no statistical change in image quality (p>0.74) and no interference in raw data for a 20  20 cm radiation field. The coil was found to be efficient over large volumes and negligible RF heating was observed. Volunteer scans acquired in both supine and standing positions provided artefact free images with good anatomical visualisation. Conclusions: The first completely radio transparent RF coil for use on a 1.0 Tesla MRI-Linac has been described. There is no impact on either the imaging or dosimetry performance with a simultaneous radiation beam. The open design enables imaging and radiotherapy guidance in a variety of positons. . © 2018 Institute of Physics and Engineering in Medicine.

Image quality validation of Sentinel 2 Level-1 products: performance status at the beginning of the constellation routine phase

Science.gov (United States)

Francesconi, Benjamin; Neveu-VanMalle, Marion; Espesset, Aude; Alhammoud, Bahjat; Bouzinac, Catherine; Clerc, Sébastien; Gascon, Ferran

2017-09-01

Sentinel-2 is an Earth Observation mission developed by the European Space Agency (ESA) in the frame of the Copernicus program of the European Commission. The mission is based on a constellation of 2-satellites: Sentinel-2A launched in June 2015 and Sentinel-2B launched in March 2017. It offers an unprecedented combination of systematic global coverage of land and coastal areas, a high revisit of five days at the equator and 2 days at mid-latitudes under the same viewing conditions, high spatial resolution, and a wide field of view for multispectral observations from 13 bands in the visible, near infrared and short wave infrared range of the electromagnetic spectrum. The mission performances are routinely and closely monitored by the S2 Mission Performance Centre (MPC), including a consortium of Expert Support Laboratories (ESL). This publication focuses on the Sentinel-2 Level-1 product quality validation activities performed by the MPC. It presents an up-to-date status of the Level-1 mission performances at the beginning of the constellation routine phase. Level-1 performance validations routinely performed cover Level-1 Radiometric Validation (Equalisation Validation, Absolute Radiometry Vicarious Validation, Absolute Radiometry Cross-Mission Validation, Multi-temporal Relative Radiometry Vicarious Validation and SNR Validation), and Level-1 Geometric Validation (Geolocation Uncertainty Validation, Multi-spectral Registration Uncertainty Validation and Multi-temporal Registration Uncertainty Validation). Overall, the Sentinel-2 mission is proving very successful in terms of product quality thereby fulfilling the promises of the Copernicus program.

Complex titanates Sr_1_-_xPb_xLi_2Ti_6O_1_4 (0≤x≤1) as anode materials for high-performance lithium-ion batteries

International Nuclear Information System (INIS)

Qian, Shangshu; Yu, Haoxiang; Yan, Lei; Li, Peng; Lin, Xiaoting; Wu, Yaoyao; Long, Nengbing; Shui, Miao; Shu, Jie

2016-01-01

Highlights: • Sr_1_-_xPb_xLi_2Ti_6O_1_4 (0≤x≤1) is prepared by a simple solid state reaction. • Sr_0_._5Pb_0_._5Li_2Ti_6O_1_4 exhibits enhanced lithium storage capability. • Sr_0_._5Pb_0_._5Li_2Ti_6O_1_4 can deliver a capacity of 141.8 mAh g"−"1 at 700 mA g"−"1. • In-situ XRD is performed to study the reversibility of Sr_1_-_xPb_xLi_2Ti_6O_1_4. - Abstract: With the Pb doping content at Sr-site increasing, a series of Sr_1_-_xPb_xLi_2Ti_6O_1_4 (x = 0, 0.25, 0.50, 0.75, 1.0) are synthesized by a simple solid-state reaction. It is found that the reversible capacity and rate capability experience a parabolic course from SrLi_2Ti_6O_1_4 to PbLi_2Ti_6O_1_4. Among all the as-prepared samples, Sr_0_._5Pb_0_._5Li_2Ti_6O_1_4 shows the best cycling and rate properties. It delivers an initial charge capacity of 163.2 mAh g"−"1 at 100 mA g"−"1 with the capacity retention of 96.08% after 100 cycles. In addition, it can also deliver a reversible capacity of 141.8 mAh g"−"1 at 700 mA g"−"1. The superior electrochemical properties of Sr_0_._5Pb_0_._5Li_2Ti_6O_1_4 are attributed to the reduced charge transfer resistance and increased lithium-ion diffusion coefficient after doping. Besides, in-situ X-ray diffraction is also performed to investigate the lithium-ion insertion/extraction behaviors of SrLi_2Ti_6O_1_4, Sr_0_._5Pb_0_._5Li_2Ti_6O_1_4 and PbLi_2Ti_6O_1_4. The observed results confirm that Sr_0_._5Pb_0_._5Li_2Ti_6O_1_4 has good structural stability and reversibility for repeated lithium storage.

Enhanced Electrochemical Activity and Chromium Tolerance of the Nucleation-Agent-Free La2Ni0.9Fe0.1O4+δ Cathode by Gd0.1Ce0.9O1.95 Incorporation

Science.gov (United States)

Ling, Yihan; Xie, Huixin; Liu, Zijing; Du, Xiaoni; Chen, Hui; Ou, Xuemei; Zhao, Ling; Budiman, Riyan Achmad

2018-03-01

For the sake of improving the electrochemical activity and chromium tolerance of the K2NiF4-type oxide, La2NiO4+δ (LNO), with nonnucleation agents like Mn and Sr elements, the electrochemical performance and degradation were comparatively studied at two cathodes La2Ni0.9Fe0.1O4+δ (LNF) and LNF-40wt%Gd0.1Ce0.9O1.95 (LNF-GDC) on the GDC electrolyte, where 5wt%Cr2O3 incorporation provides Cr-containing atmosphere. Compared with non-doped LNO, LNF shows a higher interstitial oxygen concentration (δ = 0.298) and a lower electrical conductivity, where bivalent Ni ion, {Ni}_{Ni}^{ × } , and trivalent Ni ion, {Ni}_{Ni}^{ \\cdot } , and trivalent Fe ion on Ni-site, {Fe}_{Ni}^{ \\cdot } , were observed from the XPS measurements. LNF-GDC shows greatly reduced interfacial polarization resistances (Rp), which are only half of those of LNF, indicating a better electrochemical performance. More importantly, no significant degradation of LNF-GDC in performance has been observed under exposure of Cr-containing atmosphere at 700 °C for 350 h, while Rp of LNF increased by nearly 20%, suggesting LNF by GDC incorporation can enhance the electrochemical performance as well as chromium tolerance for intermediate temperature solid oxide fuel cells (IT-SOFCs).

Screening the nutritional status in oncology: a preliminary report on 1,000 outpatients.

Science.gov (United States)

Bozzetti, Federico

2009-03-01

This study presents the preliminary data of a prospective multi-centre investigation on the screening of the nutritional status of cancer outpatients with the purpose to define: (1) prevalence and rate of weight loss and nutritional risk in this patient population, and (2) to assess the association among some patient-dependent, tumour-dependent and therapy-dependent variables with the nutritional status and the nutritional risk. Seventeen centres were involved to collect demographic data (age and sex), oncologic data (site of primary tumour, stage, Eastern Cooperative Oncology Group Performance State, oncologic therapy) and presence and severity of systemic and digestive/nutritional symptoms (fatigue, anorexia, nausea/vomiting, early satiety, dysgeusia/dysosmia, dysphagia/odynophagia, diarrhoea/constipation). Furthermore, the percentage of the weight loss on the usual body weight and the body mass index were computed. The nutritional risk was assessed according to the Nutrition Risk Screening 2002 questionnaire which scores the risk from 0 to 7. On the first 1,000 screened patients, a significant weight loss (>or=10%) and a nutritional risk score >or=3 were observed in 39.7% and 33.8% of patients, respectively. Weight loss was higher in upper gastrointestinal tumours, in advanced stages of disease and in patients with a poor performance status. Similarly, the nutritional risk was higher in esophageal and pancreatic cancer and in those with a worse performance status. There was a good correlation between the severity of anorexia and the rate of the weight loss The majority of patients with no weight loss or a weight loss anorexia. Weight loss and nutritional risk are frequent in an unselected series of cancer outpatients. Site of primary tumour, stage and performance state appear to be associated, at a preliminary analysis, with significant weight loss and nutritional risk. Anorexia and weight loss are closely related, and this supports the concept that nutritional

Effect of Nb and F Co-doping on Li1.2Mn0.54Ni0.13Co0.13O2 Cathode Material for High-Performance Lithium-Ion Batteries

Directory of Open Access Journals (Sweden)

Lei Ming

2018-04-01

Full Text Available The Li1.2Mn0.54−xNbxCo0.13Ni0.13O2−6xF6x (x = 0, 0.01, 0.03, 0.05 is prepared by traditional solid-phase method, and the Nb and F ions are successfully doped into Mn and O sites of layered materials Li1.2Mn0.54Co0.13Ni0.13O2, respectively. The incorporating Nb ion in Mn site can effectively restrain the migration of transition metal ions during long-term cycling, and keep the stability of the crystal structure. The Li1.2Mn0.54−xNbxCo0.13Ni0.13O2−6xF6x shows suppressed voltage fade and higher capacity retention of 98.1% after 200 cycles at rate of 1 C. The replacement of O2− by the strongly electronegative F− is beneficial for suppressed the structure change of Li2MnO3 from the eliminating of oxygen in initial charge process. Therefore, the initial coulombic efficiency of doped Li1.2Mn0.54−xNbxCo0.13Ni0.13O2−6xF6x gets improved, which is higher than that of pure Li1.2Mn0.54Co0.13Ni0.13O2. In addition, the Nb and F co-doping can effectively enhance the transfer of lithium-ion and electrons, and thus improving rate performance.

Hierarchy stability moderates the effect of status on stress and performance in humans.

Science.gov (United States)

Knight, Erik L; Mehta, Pranjal H

2017-01-03

High social status reduces stress responses in numerous species, but the stress-buffering effect of status may dissipate or even reverse during times of hierarchical instability. In an experimental test of this hypothesis, 118 participants (57.3% female) were randomly assigned to a high- or low-status position in a stable or unstable hierarchy and were then exposed to a social-evaluative stressor (a mock job interview). High status in a stable hierarchy buffered stress responses and improved interview performance, but high status in an unstable hierarchy boosted stress responses and did not lead to better performance. This general pattern of effects was observed across endocrine (cortisol and testosterone), psychological (feeling in control), and behavioral (competence, dominance, and warmth) responses to the stressor. The joint influence of status and hierarchy stability on interview performance was explained by feelings of control and testosterone reactivity. Greater feelings of control predicted enhanced interview performance, whereas increased testosterone reactivity predicted worse performance. These results provide direct causal evidence that high status confers adaptive benefits for stress reduction and performance only when the social hierarchy is stable. When the hierarchy is unstable, high status actually exacerbates stress responses.

Comorbidity and performance status in acute myeloid leukemia patients

DEFF Research Database (Denmark)

Ostgård, L S G; Nørgaard, J M; Sengeløv, H

2015-01-01

As the world population ages, the comorbidity burden in acute myeloid leukemia (AML) patients increases. Evidence on how to integrate comorbidity measures into clinical decision-making is sparse. We determined the prognostic impact of comorbidity and World Health Organization Performance Status (PS...... with an increased short- and long-term mortality (adjusted 90 day MR, PS⩾2=3.43 (95%CI=2.30-5.13); adjusted 91 day-3 year MR=1.35 (95%CI=1.06-1.74)). We propose that more patients with comorbidity may benefit from intensive chemotherapy.Leukemia advance online publication, 2 September 2014; doi:10.1038/leu.2014.234....

The status of pulmonary fibrosis in systemic sclerosis is associated with IRF5, STAT4, IRAK1, and CTGF polymorphisms.

Science.gov (United States)

Zhao, Wenjie; Yue, Xiaoyang; Liu, Kuai; Zheng, Junfeng; Huang, Runda; Zou, Jun; Riemekasten, Gabriela; Petersen, Frank; Yu, Xinhua

2017-08-01

Pulmonary fibrosis (PF) is one of the leading causes of death in systemic sclerosis (SSc) patients. Although all SSc patients are characterized by autoimmunity, only part of them suffer from PF, suggesting that beside autoimmunity, some additional factors are involved in the initiation of PF in SSc. In this study, we aimed to identify genetic polymorphisms associated with the status of PF in SSc. We performed that an exhaustive search of the PubMed database was performed to identify eligible studies. Then, a comprehensive meta-analysis was performed by comparing PF + -SSc and PF - -SSc patients to identify genetic polymorphisms associated with the status of PF in SSc. Among eight SSc-associated susceptibility polymorphisms which were applied for meta-analysis, IRF5 rs2004640 polymorphism (OR 1.12; 95% CI 1.02-1.22, P = 1.39 × 10 -2 ), STAT4 rs7574865 polymorphism (OR 1.25; 95% CI 1.07-1.47, P = 5.3 × 10 -3 ), IRAK1 rs1059702 polymorphism (OR 1.20; 95% CI 1.05-1.37, P = 0.007), and CTGF G-945C polymorphism (OR 1.42; 95% CI 1.18-1.71, P = 0.002) are associated with PF status in SSc, while TNFAIP3 rs5029939, CD226 rs763361, CD247 rs2056626, and IRF5 rs10488631 polymorphisms are not. Since IRF5, STAT4, and IRAK1 are important regulatory factors in the control of innate immune responses and CTGF is involved in the synthesis of extracellular matrix, these results suggest a role of the innate immunity and matrix compounds in the pathogenesis of PF in SSc.

Low perinatal zinc status is not associated with the risk of type 1 diabetes in children

DEFF Research Database (Denmark)

Kyvsgaard, Julie N.; Overgaard, Anne J.; Jacobsen, Louise D.

2017-01-01

-based case-control study based on data from Danish Childhood Diabetes Register and the Danish Newborn Screening Biobank. Cases and controls were matched by birth year and month. Zinc status was analyzed in dried blood spots collected 5 to 7 days after birth. Logistic regression model was used to test...... the influence of zinc on risk of T1D. Linear regression modeling was used to examine the association between zinc status and covariates as well as age at onset. Zinc status was adjusted for HLA-DQB1 genotype, birth data and maternal age. RESULTS: Each doubling in perinatal zinc status was not associated with T1......D risk; odds ratio (OR) = 1.06 (95% confidence interval [CI] 0.84, 1.32) ( P  = 0.62), adjusted for birth year and season. This finding persisted after adjustment for possible confounders; OR = 1.01 (95% CI 0.77, 1.34) ( P  = 0.93). In none of the cohorts there were significant associations to age...

Growth performance, immune status and organ morphometry in ...

African Journals Online (AJOL)

Growth performance, immune status and organ morphometry in broilers fed Bacillus subtilis -supplemented diet. ... In conclusion, B. subtilis-type probiotics contributed positively to better growth performance, improved immune system and modulated morphology of lymphoid organs and gut mucosa in broilers. Keywords: ...

Probing ultrafast dynamics in electronic structure of epitaxial Gd(0 0 0 1) on W(1 1 0)

Energy Technology Data Exchange (ETDEWEB)

Beaulieu, Nathan [Synchrotron SOLEIL, L’Orme des Merisiers, Saint-Aubin BP 48, 91192 Gif-sur-Yvette Cedex (France); Malinowski, Gregory [Laboratoire de Physique des Solides, Université Paris Sud, Orsay (France); Bendounan, Azzedine; Silly, Mathieu G.; Chauvet, Christian [Synchrotron SOLEIL, L’Orme des Merisiers, Saint-Aubin BP 48, 91192 Gif-sur-Yvette Cedex (France); Krizmancic, Damjan [Instituto Officina dei Materiali (IOM)-CNR Laboratorio TASC, in Area Science Park S.S.14, Km 163.5, I-34149 Trieste (Italy); Sirotti, Fausto [Synchrotron SOLEIL, L’Orme des Merisiers, Saint-Aubin BP 48, 91192 Gif-sur-Yvette Cedex (France)

2013-08-15

Highlights: •Study of the magnetism of epitaxial Gd(0 0 0 1)/W(1 1 0). •Study of Gd(0 0 0 1) band structure as a function of the temperature. •Study of the Gd magnetism dynamics probing the M5 edge. -- Abstract: The electronic and magnetic properties of Gd have been studied using time- and angle-resolved photoelectron spectroscopy employing laser pump and synchrotron radiation probe pulses. The static temperature evolution of the valence band and more precisely, the 5d6s exchange splitting is reported. Ultrafast demagnetization is measured using dichroic resonant Auger spectroscopy. Remarkably, a complete demagnetization is observed followed up by a non-monotonic recovery that could be associated to magnetization oscillations.

Piezoresistance of Silicon and Strained Si0.9Ge0.1

DEFF Research Database (Denmark)

Richter, Jacob; Hansen, Ole; Larsen, A. Nylandsted

2005-01-01

We present experimentally obtained results of the piezoresistive effect in p-type silicon and strained Si0.9Ge0.1. Today, strained Si1-xGex is used for high speed electronic devices. This paper investigates if this area of use can be expanded to also cover piezoresistive micro electro mechanical...... systems (MEMS) devices. The measurements are performed on microfabricated test chips where resistors are defined in layers grown by molecular beam epitaxy on (0 0 1) silicon substrates. A uniaxial stress along the [1 1 0] direction is applied to the chip, with the use of a four point bending fixture....... The investigation covers materials with doping levels of N-A = 10(18) cm(-3) and NA = 1019 cm(-3), respectively. The results show that the pi(66) piezoresistive coefficient in strained Si0.9Ge0.1 is approximately 30% larger than the comparable pi(44) piezoresistive coefficient in silicon at a doping level of N...

IL1RN and KRT13 Expression in Bladder Cancer: Association with Pathologic Characteristics and Smoking Status

Directory of Open Access Journals (Sweden)

Thomas S. Worst

2014-01-01

Full Text Available Purpose. To validate microarray data on cytokeratin 13 (KRT13 and interleukin-1 receptor antagonist (IL1RN expression in urothelial carcinoma of the urinary bladder (UCB and to correlate our findings with pathologic characteristics and tobacco smoking. Methods. UCB tissue samples (n=109 and control samples (n=14 were obtained from transurethral resection and radical cystectomy specimens. Immunohistochemical staining of KRT13 and IL1RN was performed and semiquantitative expression scores were assessed. Smoking status was evaluated using a standardized questionnaire. Expression scores were correlated with pathologic characteristics (tumor stage and grade and with smoking status. Results. Loss of KRT13 and IL1RN expression was observed in UCB tissue samples when compared to controls (P=0.007, P=0.008 in which KRT13 and IL1RN expression were high. IL1RN expression was significantly reduced in muscle-invasive tumors (P=0.003. In tissue samples of current smokers, a significant downregulation of IL1RN was found when compared to never smokers (P=0.013. Conclusion. Decreased expressions of KRT13 and IL1RN are common features of UCB and are associated with aggressive disease. Tobacco smoking may enhance the loss of IL1RN, indicating an overweight of proinflammatory mediators involved in UCB progression. Further validation of the influence of smoking on IL1RN expression is warranted.

Quality of life and performance status in patients with pancreatic and periampullary tumors

International Nuclear Information System (INIS)

Velanovich, V.; Wollner, I.

2011-01-01

The background of this study was to determine if pretreatment quality of life is associated with performance status in patients with pancreatic and periampullary tumors. Eighty consecutive patients evaluated for surgical treatment of pancreatic or periampullary tumors completed the social functioning SF-36, a generic quality of life instrument. This instrument measures 8 domains of quality of life: physical functioning (PF), role-physical (RP), role-emotional, bodily pain, vitality, mental health, social functioning, and general health (GH). The best possible score is 100 and the worst possible score is 0. Each patient was then assigned a Karnofsky performance score (KPS), with the best possible score of 100 (normal, no complaints, no evidence of disease) and worst score of 0 (dead). Data recorded included age, gender, pathology, stage, resection, use of chemotherapy, and radiation therapy. Statistical analysis was done using single and multiple linear regression analysis, correlation coefficients (r) and coefficient of determination (r 2 ). KPS was significantly associated with all domains of the SF-36 by single linear regression. By multiple linear regression, KPS was significantly associated with the PF domain (p 2 values) suggest that there are additional factors determining both quality of life and performance status in patients with pancreatic and periampullary tumors. (author)

Morphologically well-defined Gd0.1Ce0.9O1.95 embedded Ba0.5Sr0.5Co0.8Fe0.2O3-δ nanofiber with an enhanced triple phase boundary as cathode for low-temperature solid oxide fuel cells

Science.gov (United States)

Kim, Chanho; Park, Hyunjung; Jang, Inyoung; Kim, Sungmin; Kim, Kijung; Yoon, Heesung; Paik, Ungyu

2018-02-01

Controlling triple phase boundary (TPB), an intersection of the ionic conductor, electronic conductor and gas phase as a major reaction site, is a key to improve cell performances for low-temperature solid oxide fuel cells. We report a synthesis of morphologically well-defined Gd0.1Ce0.9O1.95 (GDC) embedded Ba0.5Sr0.5Co0.8Fe0.2O3-δ (BSCF) nanofibers and their electrochemical performances as a cathode. Electrospun fibers prepared with a polymeric solution that contains crystalline Ba0.5Sr0.5Co0.8Fe0.2O3-δ particles in ∼200 nm size and Gd(NO3)3/Ce(NO3)3 precursors in an optimized weight ratio of 3 to 2 result in one dimensional structure without severe agglomeration and morphological collapse even after a high calcination at 1000 °C. As-prepared nanofibers have fast electron pathways along the axial direction of fibers, a higher surface area of 7.5 m2 g-1, and more oxygen reaction sites at TPBs than those of GDC/BSCF composite particles and core-shell nanofibers. As a result, the Gd0.1Ce0.9O1.95 embedded Ba0.5Sr0.5Co0.8Fe0.2O3-δ nanofiber cell shows excellent performances of the maximum power density of 0.65 W cm-2 at 550 °C and 1.02 W cm-2 at 600 °C, respectively.

WE-E-12A-01: Medical Physics 1.0 to 2.0: MRI, Displays, Informatics

International Nuclear Information System (INIS)

Pickens, D; Flynn, M; Peck, D

2014-01-01

Medical Physics 2.0 is a bold vision for an existential transition of clinical imaging physics in face of the new realities of value-based and evidence-based medicine, comparative effectiveness, and meaningful use. It speaks to how clinical imaging physics can expand beyond traditional insular models of inspection and acceptance testing, oriented toward compliance, towards team-based models of operational engagement, prospective definition and assurance of effective use, and retrospective evaluation of clinical performance. Organized into four sessions of the AAPM, this particular session focuses on three specific modalities as outlined below. MRI 2.0: This presentation will look into the future of clinical MR imaging and what the clinical medical physicist will need to be doing as the technology of MR imaging evolves. Many of the measurement techniques used today will need to be expanded to address the advent of higher field imaging systems and dedicated imagers for specialty applications. Included will be the need to address quality assurance and testing metrics for multi-channel MR imagers and hybrid devices such as MR/PET systems. New pulse sequences and acquisition methods, increasing use of MR spectroscopy, and real-time guidance procedures will place the burden on the medical physicist to define and use new tools to properly evaluate these systems, but the clinical applications must be understood so that these tools are use correctly. Finally, new rules, clinical requirements, and regulations will mean that the medical physicist must actively work to keep her/his sites compliant and must work closely with physicians to ensure best performance of these systems. Informatics Display 1.0 to 2.0: Medical displays are an integral part of medical imaging operation. The DICOM and AAPM (TG18) efforts have led to clear definitions of performance requirements of monochrome medical displays that can be followed by medical physicists to ensure proper performance. However

WE-E-12A-01: Medical Physics 1.0 to 2.0: MRI, Displays, Informatics

Energy Technology Data Exchange (ETDEWEB)

Pickens, D [Vanderbilt Medical Center, Nashville, TN (United States); Flynn, M; Peck, D [Henry Ford Health System, Detroit, MI (United States)

2014-06-15

Medical Physics 2.0 is a bold vision for an existential transition of clinical imaging physics in face of the new realities of value-based and evidence-based medicine, comparative effectiveness, and meaningful use. It speaks to how clinical imaging physics can expand beyond traditional insular models of inspection and acceptance testing, oriented toward compliance, towards team-based models of operational engagement, prospective definition and assurance of effective use, and retrospective evaluation of clinical performance. Organized into four sessions of the AAPM, this particular session focuses on three specific modalities as outlined below. MRI 2.0: This presentation will look into the future of clinical MR imaging and what the clinical medical physicist will need to be doing as the technology of MR imaging evolves. Many of the measurement techniques used today will need to be expanded to address the advent of higher field imaging systems and dedicated imagers for specialty applications. Included will be the need to address quality assurance and testing metrics for multi-channel MR imagers and hybrid devices such as MR/PET systems. New pulse sequences and acquisition methods, increasing use of MR spectroscopy, and real-time guidance procedures will place the burden on the medical physicist to define and use new tools to properly evaluate these systems, but the clinical applications must be understood so that these tools are use correctly. Finally, new rules, clinical requirements, and regulations will mean that the medical physicist must actively work to keep her/his sites compliant and must work closely with physicians to ensure best performance of these systems. Informatics Display 1.0 to 2.0: Medical displays are an integral part of medical imaging operation. The DICOM and AAPM (TG18) efforts have led to clear definitions of performance requirements of monochrome medical displays that can be followed by medical physicists to ensure proper performance. However

Oxygen permeation in thin, dense Ce0.9Gd0.1O 1.95- membranes I. Model study

DEFF Research Database (Denmark)

Chatzichristodoulou, Christodoulos; Søgaard, Martin; Hendriksen, Peter Vang

2011-01-01

at the feed and permeate side of the membrane, related to the gaseous oxygen reduction and fuel oxidation, respectively, as well as the gas conversion and gas diffusion resistances in the porous support structure at the permeate side. The temperature and oxygen activity dependence of the oxide ionic...... was analyzed by a separation of the various losses. The chemical expansion of Ce 0.9Gd0.1O1.95-δ under operation was estimated from the calculated oxygen activity and nonstoichiometry profiles inside the membrane. © 2011 The Electrochemical Society.......A model of a supported planar Ce0.9Gd0.1O 1.95-δ oxygen membrane in a plug-flow setup was constructed and a sensitivity analysis of its performance under varying operating conditions and membrane parameters was performed. The model takes into account the driving force losses at the catalysts...

Observation of $B^0_s\\rightarrow\\chi_{c1}\\phi$ decay and study of $B^0\\rightarrow\\chi_{c1,2}K^{*0}$ decays

CERN Document Server

INSPIRE-00258707; Adeva, B; Adinolfi, M; Adrover, C; Affolder, A; Ajaltouni, Z; Albrecht, J; Alessio, F; Alexander, M; Ali, S; Alkhazov, G; Alvarez Cartelle, P; Alves Jr, A A; Amato, S; Amerio, S; Amhis, Y; Anderlini, L; Anderson, J; Andreassen, R; Andrews, J E; Appleby, R B; Aquines Gutierrez, O; Archilli, F; Artamonov, A; Artuso, M; Aslanides, E; Auriemma, G; Baalouch, M; Bachmann, S; Back, J J; Baesso, C; Balagura, V; Baldini, W; Barlow, R J; Barschel, C; Barsuk, S; Barter, W; Bauer, Th; Bay, A; Beddow, J; Bedeschi, F; Bediaga, I; Belogurov, S; Belous, K; Belyaev, I; Ben-Haim, E; Bencivenni, G; Benson, S; Benton, J; Berezhnoy, A; Bernet, R; Bettler, M -O; van Beuzekom, M; Bien, A; Bifani, S; Bird, T; Bizzeti, A; Bjørnstad, P M; Blake, T; Blanc, F; Blouw, J; Blusk, S; Bocci, V; Bondar, A; Bondar, N; Bonivento, W; Borghi, S; Borgia, A; Bowcock, T J V; Bowen, E; Bozzi, C; Brambach, T; van den Brand, J; Bressieux, J; Brett, D; Britsch, M; Britton, T; Brook, N H; Brown, H; Burducea, I; Bursche, A; Busetto, G; Buytaert, J; Cadeddu, S; Callot, O; Calvi, M; Calvo Gomez, M; Camboni, A; Campana, P; Campora Perez, D; Carbone, A; Carboni, G; Cardinale, R; Cardini, A; Carranza-Mejia, H; Carson, L; Carvalho Akiba, K; Casse, G; Castillo Garcia, L; Cattaneo, M; Cauet, Ch; Cenci, R; Charles, M; Charpentier, Ph; Chen, P; Chiapolini, N; Chrzaszcz, M; Ciba, K; Cid Vidal, X; Ciezarek, G; Clarke, P E L; Clemencic, M; Cliff, H V; Closier, J; Coca, C; Coco, V; Cogan, J; Cogneras, E; Collins, P; Comerma-Montells, A; Contu, A; Cook, A; Coombes, M; Coquereau, S; Corti, G; Couturier, B; Cowan, G A; Craik, D C; Cunliffe, S; Currie, R; D'Ambrosio, C; David, P; David, P N Y; Davis, A; De Bonis, I; De Bruyn, K; De Capua, S; De Cian, M; De Miranda, J M; De Paula, L; De Silva, W; De Simone, P; Decamp, D; Deckenhoff, M; Del Buono, L; Déléage, N; Derkach, D; Deschamps, O; Dettori, F; Di Canto, A; Di Ruscio, F; Dijkstra, H; Dogaru, M; Donleavy, S; Dordei, F; Dosil Suárez, A; Dossett, D; Dovbnya, A; Dupertuis, F; Dzhelyadin, R; Dziurda, A; Dzyuba, A; Easo, S; Egede, U; Egorychev, V; Eidelman, S; van Eijk, D; Eisenhardt, S; Eitschberger, U; Ekelhof, R; Eklund, L; El Rifai, I; Elsasser, Ch; Elsby, D; Falabella, A; Färber, C; Fardell, G; Farinelli, C; Farry, S; Fave, V; Ferguson, D; Fernandez Albor, V; Ferreira Rodrigues, F; Ferro-Luzzi, M; Filippov, S; Fiore, M; Fitzpatrick, C; Fontana, M; Fontanelli, F; Forty, R; Francisco, O; Frank, M; Frei, C; Frosini, M; Furcas, S; Furfaro, E; Gallas Torreira, A; Galli, D; Gandelman, M; Gandini, P; Gao, Y; Garofoli, J; Garosi, P; Garra Tico, J; Garrido, L; Gaspar, C; Gauld, R; Gersabeck, E; Gersabeck, M; Gershon, T; Ghez, Ph; Gibson, V; Giubega, L; Gligorov, V V; Göbel, C; Golubkov, D; Golutvin, A; Gomes, A; Gordon, H; Grabalosa Gándara, M; Graciani Diaz, R; Granado Cardoso, L A; Graugés, E; Graziani, G; Grecu, A; Greening, E; Gregson, S; Griffith, P; Grünberg, O; Gui, B; Gushchin, E; Guz, Yu; Gys, T; Hadjivasiliou, C; Haefeli, G; Haen, C; Haines, S C; Hall, S; Hamilton, B; Hampson, T; Hansmann-Menzemer, S; Harnew, N; Harnew, S T; Harrison, J; Hartmann, T; He, J; Head, T; Heijne, V; Hennessy, K; Henrard, P; Hernando Morata, J A; van Herwijnen, E; Hicheur, A; Hicks, E; Hill, D; Hoballah, M; Holtrop, M; Hombach, C; Hopchev, P; Hulsbergen, W; Hunt, P; Huse, T; Hussain, N; Hutchcroft, D; Hynds, D; Iakovenko, V; Idzik, M; Ilten, P; Jacobsson, R; Jaeger, A; Jans, E; Jaton, P; Jawahery, A; Jing, F; John, M; Johnson, D; Jones, C R; Joram, C; Jost, B; Kaballo, M; Kandybei, S; Kanso, W; Karacson, M; Karbach, T M; Kenyon, I R; Ketel, T; Keune, A; Khanji, B; Kochebina, O; Komarov, I; Koopman, R F; Koppenburg, P; Korolev, M; Kozlinskiy, A; Kravchuk, L; Kreplin, K; Kreps, M; Krocker, G; Krokovny, P; Kruse, F; Kucharczyk, M; Kudryavtsev, V; Kvaratskheliya, T; La Thi, V N; Lacarrere, D; Lafferty, G; Lai, A; Lambert, D; Lambert, R W; Lanciotti, E; Lanfranchi, G; Langenbruch, C; Latham, T; Lazzeroni, C; Le Gac, R; van Leerdam, J; Lees, J -P; Lefèvre, R; Leflat, A; Lefrançois, J; Leo, S; Leroy, O; Lesiak, T; Leverington, B; Li, Y; Li Gioi, L; Liles, M; Lindner, R; Linn, C; Liu, B; Liu, G; Lohn, S; Longstaff, I; Lopes, J H; Lopez-March, N; Lu, H; Lucchesi, D; Luisier, J; Luo, H; Machefert, F; Machikhiliyan, I V; Maciuc, F; Maev, O; Malde, S; Manca, G; Mancinelli, G; Marconi, U; Märki, R; Marks, J; Martellotti, G; Martens, A; Martín Sánchez, A; Martinelli, M; Martinez Santos, D; Martins Tostes, D; Massafferri, A; Matev, R; Mathe, Z; Matteuzzi, C; Maurice, E; Mazurov, A; Mc Skelly, B; McCarthy, J; McNab, A; McNulty, R; Meadows, B; Meier, F; Meissner, M; Merk, M; Milanes, D A; Minard, M -N; Molina Rodriguez, J; Monteil, S; Moran, D; Morawski, P; Mordà, A; Morello, M J; Mountain, R; Mous, I; Muheim, F; Müller, K; Muresan, R; Muryn, B; Muster, B; Naik, P; Nakada, T; Nandakumar, R; Nasteva, I; Needham, M; Neubert, S; Neufeld, N; Nguyen, A D; Nguyen, T D; Nguyen-Mau, C; Nicol, M; Niess, V; Niet, R; Nikitin, N; Nikodem, T; Nomerotski, A; Novoselov, A; Oblakowska-Mucha, A; Obraztsov, V; Oggero, S; Ogilvy, S; Okhrimenko, O; Oldeman, R; Orlandea, M; Otalora Goicochea, J M; Owen, P; Oyanguren, A; Pal, B K; Palano, A; Palutan, M; Panman, J; Papanestis, A; Pappagallo, M; Parkes, C; Parkinson, C J; Passaleva, G; Patel, G D; Patel, M; Patrick, G N; Patrignani, C; Pavel-Nicorescu, C; Pazos Alvarez, A; Pellegrino, A; Penso, G; Pepe Altarelli, M; Perazzini, S; Perez Trigo, E; Pérez-Calero Yzquierdo, A; Perret, P; Perrin-Terrin, M; Pessina, G; Petridis, K; Petrolini, A; Phan, A; Picatoste Olloqui, E; Pietrzyk, B; Pilař, T; Pinci, D; Playfer, S; Plo Casasus, M; Polci, F; Polok, G; Poluektov, A; Polyakov, I; Polycarpo, E; Popov, A; Popov, D; Popovici, B; Potterat, C; Powell, A; Prisciandaro, J; Pritchard, A; Prouve, C; Pugatch, V; Puig Navarro, A; Punzi, G; Qian, W; Rademacker, J H; Rakotomiaramanana, B; Rangel, M S; Raniuk, I; Rauschmayr, N; Raven, G; Redford, S; Reid, M M; dos Reis, A C; Ricciardi, S; Richards, A; Rinnert, K; Rives Molina, V; Roa Romero, D A; Robbe, P; Rodrigues, E; Rodriguez Perez, P; Roiser, S; Romanovsky, V; Romero Vidal, A; Rouvinet, J; Ruf, T; Ruffini, F; Ruiz, H; Ruiz Valls, P; Sabatino, G; Saborido Silva, J J; Sagidova, N; Sail, P; Saitta, B; Salustino Guimaraes, V; Salzmann, C; Sanmartin Sedes, B; Sannino, M; Santacesaria, R; Santamarina Rios, C; Santovetti, E; Sapunov, M; Sarti, A; Satriano, C; Satta, A; Savrie, M; Savrina, D; Schaack, P; Schiller, M; Schindler, H; Schlupp, M; Schmelling, M; Schmidt, B; Schneider, O; Schopper, A; Schune, M -H; Schwemmer, R; Sciascia, B; Sciubba, A; Seco, M; Semennikov, A; Sepp, I; Serra, N; Serrano, J; Seyfert, P; Shapkin, M; Shapoval, I; Shatalov, P; Shcheglov, Y; Shears, T; Shekhtman, L; Shevchenko, O; Shevchenko, V; Shires, A; Silva Coutinho, R; Sirendi, M; Skwarnicki, T; Smith, N A; Smith, E; Smith, J; Smith, M; Sokoloff, M D; Soler, F J P; Soomro, F; Souza, D; Souza De Paula, B; Spaan, B; Sparkes, A; Spradlin, P; Stagni, F; Stahl, S; Steinkamp, O; Stoica, S; Stone, S; Storaci, B; Straticiuc, M; Straumann, U; Subbiah, V K; Sun, L; Swientek, S; Syropoulos, V; Szczekowski, M; Szczypka, P; Szumlak, T; T'Jampens, S; Teklishyn, M; Teodorescu, E; Teubert, F; Thomas, C; Thomas, E; van Tilburg, J; Tisserand, V; Tobin, M; Tolk, S; Tonelli, D; Topp-Joergensen, S; Torr, N; Tournefier, E; Tourneur, S; Tran, M T; Tresch, M; Tsaregorodtsev, A; Tsopelas, P; Tuning, N; Ubeda Garcia, M; Ukleja, A; Urner, D; Ustyuzhanin, A; Uwer, U; Vagnoni, V; Valenti, G; Vallier, A; Van Dijk, M; Vazquez Gomez, R; Vazquez Regueiro, P; Vázquez Sierra, C; Vecchi, S; Velthuis, J J; Veltri, M; Veneziano, G; Vesterinen, M; Viaud, B; Vieira, D; Vilasis-Cardona, X; Vollhardt, A; Volyanskyy, D; Voong, D; Vorobyev, A; Vorobyev, V; Voß, C; Voss, H; Waldi, R; Wallace, C; Wallace, R; Wandernoth, S; Wang, J; Ward, D R; Watson, N K; Webber, A D; Websdale, D; Whitehead, M; Wicht, J; Wiechczynski, J; Wiedner, D; Wiggers, L; Wilkinson, G; Williams, M P; Williams, M; Wilson, F F; Wimberley, J; Wishahi, J; Witek, M; Wotton, S A; Wright, S; Wu, S; Wyllie, K; Xie, Y; Xing, Z; Yang, Z; Young, R; Yuan, X; Yushchenko, O; Zangoli, M; Zavertyaev, M; Zhang, F; Zhang, L; Zhang, W C; Zhang, Y; Zhelezov, A; Zhokhov, A; Zhong, L; Zvyagin, A

2013-01-01

The first observation of the decay $B^0_s\\rightarrow\\chi_{c1}\\phi$ and a study of $B^0\\rightarrow\\chi_{c1,2}K^{*0}$ decays are presented. The analysis is performed using a dataset, corresponding to an integrated luminosity of 1.0 fb$^{-1}$, collected by the LHCb experiment in pp collisions at a centre-of-mass energy of 7 TeV. The following ratios of branching fractions are measured: \\begin{equation*} \\begin{array}{lll} \\dfrac{\\cal{B}(B^0_s\\rightarrow\\chi_{c1}\\phi)}{\\cal{B}(B^0_s\\rightarrow J/\\psi\\phi)} &=& (18.9 \\pm1.8\\,(stat)\\pm1.3\\,(syst)\\pm0.8\\,(\\cal{B})) \\times 10^{-2}, \\\\ \\dfrac{\\cal{B}(B^0\\rightarrow\\chi_{c1}K^{*0})}{\\cal{B}(B^0\\rightarrow J/\\psi K^{*0})} &=& (19.8 \\pm1.1\\,(stat)\\pm1.2\\,(syst)\\pm0.9\\,(\\cal{B})) \\times 10^{-2}, \\\\ \\dfrac{\\cal{B}(B^0\\rightarrow\\chi_{c2}K^{*0})}{\\cal{B}(B^0\\rightarrow\\chi_{c 1}K^{*0})} &=& (17.1 \\pm5.0\\,(stat)\\pm1.7\\,(syst)\\pm1.1\\,(\\cal{B})) \\times 10^{-2}, \\\\ \\end{array} \\end{equation*} where the third uncertainty is due to the limited knowledge o...

Independent validation testing of the FLAME computer code, Version 1.0

International Nuclear Information System (INIS)

Martian, P.; Chung, J.N.

1992-07-01

Independent testing of the FLAME computer code, Version 1.0, was conducted to determine if the code is ready for use in hydrological and environmental studies at Department of Energy sites. This report describes the technical basis, approach, and results of this testing. Validation tests, (i.e., tests which compare field data to the computer generated solutions) were used to determine the operational status of the FLAME computer code and were done on a qualitative basis through graphical comparisons of the experimental and numerical data. These tests were specifically designed to check: (1) correctness of the FORTRAN coding, (2) computational accuracy, and (3) suitability to simulating actual hydrologic conditions. This testing was performed using a structured evaluation protocol which consisted of: (1) independent applications, and (2) graduated difficulty of test cases. Three tests ranging in complexity from simple one-dimensional steady-state flow field problems under near-saturated conditions to two-dimensional transient flow problems with very dry initial conditions

Crystallographic structure and magnetic properties of pseudobrookite Fe2-xNixTiO5 system (x = 0, 0.1, 0.2, 0.3, 0.5 and 1)

International Nuclear Information System (INIS)

Yosef Sarwanto and Wisnu Ari Adi

2018-01-01

Crystallographic structure and magnetic properties of pseudobrookite Fe 2-x Ni x TiO 5 system (x=0, 0.1, 0.2, 0.3 ,0.5 and 1)have been performed through solid state reaction. Pseudobrookite Fe 2-x Ni x TiO 5 system was synthesized by mixing of Fe 2 O 3 , NiO, and TiO 2 with stoichiometry composition using wet mill. The mixture was milled for 5 hours and sintered in the electric chamber furnace at 1000 °C in the air at atmosphere pressure for 5 hours. The refinement against of X-ray diffraction data shows that the samples with composition of (x = 0) and (x = 0.1) have a single phase with Fe 2 TiO 5 structure. How ever the samples with composition of (x > 0.1) consist of multiple phases, namely Fe 2-x Ni x TiO 5 , FeTiO 3 , Fe 2 NiO 4 and NiO. Particle morphologies of the composition x = 0 and x =0.1 are homogenous and uniform on the sample surface with a polygonal particle shape and particle size varies. At room temperature, the sample with x =0 is paramagnetic and that with x =0.1 is ferromagnetic. Magnetic phase transformation of this study is the caused by the present of Ni substituted Fe in the system. Thus substitution Ni into Fe on the system pseudobrookite Fe 2 TiO 5 only capable of 0.1 at.% without changing the crystal structure of the material. It means that there is an interaction between the magnetic spin Fe 3+ on the 3d 5 configurations and Ni 2 + on the 3d 3 configurations through the mechanism of double exchange. Double exchange mechanism is a magnetic type of exchange that appears between the ions Fe 3+ and Ni 2+ adjacent in different oxidation states. (author)

Microstructure optimization for high-performance PrBa0.5Sr0.5Co1.5Fe0.5O5+δ-La2NiO4+δ core-shell cathode of solid oxide fuel cells

Science.gov (United States)

Li, Jin; Qiu, Peng; Xia, Meng; Jia, Lichao; Chi, Bo; Pu, Jian; Li, Jian

2018-03-01

Four PrBa0.5Sr0.5Co1.5Fe0.5O5+δ (PBSCF)-La2NiO4+δ (LN) core-shell cathodes, designated as PL-0, PL-1, PL-3 and PL-5, are prepared by infiltrating LN solution into PBSCF scaffold, and they are investigated in terms of the effect of LN thickness on their electrochemical performance. PL-3 with a continuous LN coating of a moderate average thickness (∼9 nm) demonstrates the lowest initial polarization resistance (0.51 Ω cm2) and highest power density (0.71 W cm-2) among all the cathodes. Polarized at 400 mA cm-2 and 700 °C for up to 40 h, the polarization resistance of all the prepared cathodes increases to approach a stable level after early stage decrease due to current activation, and PL-3 exhibits a slower average rate of performance degradation (25%). The electrochemical performance improvement is mainly attributed to that LN has a relatively high oxygen surface exchange coefficient and continuous LN coating depresses Sr segregation at PBSCF/LN interface.

Influence of socioeconomic status on trauma center performance evaluations in a Canadian trauma system.

Science.gov (United States)

Moore, Lynne; Turgeon, Alexis F; Sirois, Marie-Josée; Murat, Valérie; Lavoie, André

2011-09-01

Trauma center performance evaluations generally include adjustment for injury severity, age, and comorbidity. However, disparities across trauma centers may be due to other differences in source populations that are not accounted for, such as socioeconomic status (SES). We aimed to evaluate whether SES influences trauma center performance evaluations in an inclusive trauma system with universal access to health care. The study was based on data collected between 1999 and 2006 in a Canadian trauma system. Patient SES was quantified using an ecologic index of social and material deprivation. Performance evaluations were based on mortality adjusted using the Trauma Risk Adjustment Model. Agreement between performance results with and without additional adjustment for SES was evaluated with correlation coefficients. The study sample comprised a total of 71,784 patients from 48 trauma centers, including 3,828 deaths within 30 days (4.5%) and 5,549 deaths within 6 months (7.7%). The proportion of patients in the highest quintile of social and material deprivation varied from 3% to 43% and from 11% to 90% across hospitals, respectively. The correlation between performance results with or without adjustment for SES was almost perfect (r = 0.997; 95% CI 0.995-0.998) and the same hospital outliers were identified. We observed an important variation in SES across trauma centers but no change in risk-adjusted mortality estimates when SES was added to adjustment models. Results suggest that after adjustment for injury severity, age, comorbidity, and transfer status, disparities in SES across trauma center source populations do not influence trauma center performance evaluations in a system offering universal health coverage. Copyright © 2011 American College of Surgeons. Published by Elsevier Inc. All rights reserved.

Oxidative status and serum PON1 activity in beta-thalassemia minor.

Science.gov (United States)

Selek, Sahbettin; Aslan, Mehmet; Horoz, Mehmet; Gur, Mustafa; Erel, Ozcan

2007-03-01

Paraoxonase-1 (PON1) deficiency is related to increased susceptibility to low density lipoprotein oxidation and development of atherosclerosis. The aim of this study was to investigate paraoxonase and arylesterase activities along with oxidative status parameters, and to find out if there is any increased susceptibility to atherogenesis, which might be reflected with increased oxidative stress and decreased serum PON1 activity in beta-thalassemia minor (BTM) subjects. Thirty-two subjects with BTM and 28 healthy subjects as control were enrolled in the study. Serum paraoxonase and arylesterase activities, lipid hydroperoxide (LOOH) levels, total antioxidant capacity (TAC), total oxidant status (TOS) and oxidative stress index (OSI) were determined. Serum TAC, paraoxonase and arylesterase activities were significantly lower in BTM subjects than controls (for all p<0.001), while TOS, LOOH levels and OSI were significantly higher (p<0.001, p<0.05 and p<0.001; respectively). In BTM subjects, OSI, TOS, LOOH levels and TAC were significantly correlated with serum paraoxonase (r=-0.245, p<0.05; r=-0.231, p<0.05; r=-0.264, p<0.05 and, r=0.342, p<0.05, respectively) and arylesterase activities (r=-0.332, p<0.05, r=-0.308, p<0.05; r=-0.320, p<0.05 and r=0.443, p<0.05). Additionally, hemoglobin level was also correlated with serum paraoxonase (r=0.501, p<0.001) and arylesterase activities (r=0.501, p<0.001), TAC (r=0.402, p<0.05), TOS (r=-0.274, p<0.05) and OSI (r=-0.352, p<0.05). Oxidative stress is increased, while serum PON1 activity is decreased in BTM subjects. Decrease in PON1 activity seems to be associated with both the degree of oxidative stress and anemia. BTM subjects may be more prone to development of atherogenesis due to low serum PON1 activity.

The expression status of TRX, AR, and cyclin D1 correlates with clinicopathological characteristics and ER status in breast cancer.

Science.gov (United States)

Huang, Weisun; Nie, Weiwei; Zhang, Wenwen; Wang, Yanru; Zhu, Aiyu; Guan, Xiaoxiang

2016-01-01

The ER signaling pathway plays a critical role in breast cancer. ER signaling pathway-related proteins, such as TRX, AR, and cyclin D1, may have an important function in breast cancer. However, the ways that they influence breast cancer development and progression are still unclear. A total of 101 Chinese female patients diagnosed with invasive ductal breast adenocarcinoma were retrospectively enrolled in the study. The expression levels of TRX, AR, and cyclin D1 were detected by immunohistochemistry and analyzed via correlation with clinicopathological characteristics and the expression status of ER, PR, and HER2. The expression status of TRX, AR, and cyclin D1 was not associated with the patient's age, menopausal status, tumor size, or histological differentiation (P>0.05), but was positively correlated with ER and PR (PTRX-positive patients were also HER2-positive (P=0.003). Of AR- or cyclin D1-positive patients, most had relatively earlier I-II tumor stage (P=0.005 and P=0.047, respectively) and no metastatic lymph node involvement (P=0.008 and P=0.005, respectively). TRX was found to be positively correlated with ER and PR expression, whereas it was negatively correlated with HER2 expression. In addition, we found that the positive expression of AR and cyclin D1 was correlated with lower TNM stage and fewer metastatic lymph nodes, and it was more common in ER-positive breast cancer than in the basal-like subtype. This may indicate that AR and cyclin D1 are good predictive and prognostic factors and closely interact with ER signaling pathway. Further studies will be necessary to investigate the response and clinical outcomes of treatment targeting TRX, AR, and cyclin D1.

Effect of magnetic field on the microstructure and electrochemical performance of rapidly quenched La{sub 0.1}Nd{sub 0.075}Mg{sub 0.04}Ni{sub 0.65}Co{sub 0.12} alloy

Energy Technology Data Exchange (ETDEWEB)

Chen, Xiangrong [College of Chemistry and Chemical Engineering, Central South University, Changsha 410083 (China); Wang, Haiyan, E-mail: wanghy419@126.com [College of Chemistry and Chemical Engineering, Central South University, Changsha 410083 (China); Hunan Dahua New Energy Co., Ltd., Changsha 410600 (China); Zhu, Shuping; Li, Fangfang [College of Chemistry and Chemical Engineering, Central South University, Changsha 410083 (China); Tang, Yougen, E-mail: ygtang@csu.edu.cn [College of Chemistry and Chemical Engineering, Central South University, Changsha 410083 (China); Liu, Zuming [State Key Laboratory for Powder Metallurgy, Central South University, Changsha 410083 (China)

2014-12-25

Highlights: • La{sub 0.1}Nd{sub 0.075}Mg{sub 0.04}Ni{sub 0.65}Co{sub 0.12} alloy is rapidly quenched in a 0.18 T static magnetic field. • The multiphase structures of as-treated alloys remain unchanged. • Grain refinement is achieved with the aid of magnetic field. • Magnetic field favors the formation of La{sub 2}Ni{sub 7} phase. • The as-prepared alloy exhibits improved electrochemical performance. - Abstract: Rare earth–Mg–Ni-based (RE–Mg–Ni-based) La{sub 0.1}Nd{sub 0.075}Mg{sub 0.04}Ni{sub 0.65}Co{sub 0.12} hydrogen storage alloys were rapidly quenched with and without exerting a 0.18 T static magnetic field and investigated by X-ray diffraction (XRD), scanning electron microscope (SEM), energy dispersive spectroscopy (EDS) studies and various electrochemical measurements. The results show that all samples hold a two-phase structure consisting of La{sub 2}Ni{sub 7} phase and LaNi{sub 5} phase, suggesting that the structure remains unchanged after treatment. Grain refinement, homogeneous composition and increase in La{sub 2}Ni{sub 7} phase abundance are achieved when magnetic field is applied. In comparison to quenched alloys, higher discharge capacities are obtained for the alloys prepared with the aid of magnetic field mainly due to the larger La{sub 2}Ni{sub 7} phase abundance. Cycling stability is improved with increasing quenching rate probably owing to better anti-pulverization ability resulted from refined grain size. Ameliorated electrochemical kinetics of the magnetic field assisted rapidly quenched alloys has been confirmed by potential-step measurements and electrochemical impedance spectroscopy (EIS) tests in accordance with the enhanced electrochemical properties.

First-principles calculations of the electronic structure and optical properties of K1−xNaxTaO3 (x=0, 0.25, 0.5, 0.75, 1)

International Nuclear Information System (INIS)

Zhao, Na; Wang, Yue-Hua; Wang, Qing-Xi; Hu, Wen-Jing

2012-01-01

The first-principles calculations are performed to investigate the cubic phase composite K 1−x Na x TaO 3 (x=0, 0.25, 0.5, 0.75, 1), by using density functional theory (DFT) with the full potential linearized augmented plane wave (FP-LAPW) method. The energy band structures, density of states (DOS), electron density and optical properties are obtained. The results show that Na ion plays an important role in K 1−x Na x TaO 3 . With the content of Na ion increasing, the changes of lattice parameters, energy gaps, bond lengths and optical properties of K 1−x Na x TaO 3 are regular. Moreover, the dependence of ferroelectric photocatalysis on both optical properties and internal electronic structure are analyzed in detail. It is proposed that the doped materials are promising photocatalytic materials. - Graphical abstract: The density of states (DOS) of K 1−x Na x TaO 3 (x=0.5). Highlights: ► The first-principles calculations are performed, by using DFT with FP-LAPW method. ► The changes of internal electronic structure and optical property of doped materials are regular. ► The dependence of ferroelectric photocatalysis on optical properties is analyzed. ► The dependence of ferroelectric photocatalysis on internal electronic structure is analyzed. ► The doped materials are promising photocatalytic materials.

Randomized phase II study of gefitinib compared with placebo in chemotherapy-naive patients with advanced non-small-cell lung cancer and poor performance status.

Science.gov (United States)

Goss, Glenwood; Ferry, David; Wierzbicki, Rafal; Laurie, Scott A; Thompson, Joyce; Biesma, Bonne; Hirsch, Fred R; Varella-Garcia, Marileila; Duffield, Emma; Ataman, Ozlem U; Zarenda, Marc; Armour, Alison A

2009-05-01

To compare gefitinib with placebo in chemotherapy naïve patients with advanced non-small-cell lung cancer (NSCLC) and poor performance status. NSCLC patients (chemotherapy naïve, WHO performance status 2 or 3; unfit for chemotherapy; stage IIIB/IV) were randomly assigned to gefitinib (250 mg/d) plus best supportive care (BSC; n = 100) or placebo plus BSC (n = 101). The primary end point was progression-free survival (PFS). Secondary end points included overall survival (OS), objective response rate (ORR), quality of life (QOL), pulmonary symptom improvement (PSI), and safety. Correlation of gefitinib efficacy with EGFR gene copy number (fluorescent in situ hybridization [FISH]) was explored. Hazard ratios (HRs; gefitinib:placebo) were 0.82 (95% CI, 0.60 to 1.12; P = .217) for PFS and 0.84 (95% CI, 0.62 to 1.15; P = .272) for OS. As expected for this patient population, OS for both arms was poor, at about 3 months. ORRs were 6.0% (gefitinib) and 1.0% (placebo). QOL and PSI rates were 21.1% and 28.3% (gefitinib) and 20.0% and 28.3% (placebo), respectively. In EGFR FISH-positive patients (n = 32), HRs were 0.29 (95% CI, 0.11 to 0.73) for PFS and 0.44 (95% CI, 0.17 to 1.12) for OS. No unexpected adverse events occurred. There was no statistically significant difference in PFS, OS, and ORRs after treatment with gefitinib or placebo, in the overall population; improvements in QOL and symptoms were similar in both groups. Tolerability profile of gefitinib was consistent with previous studies. PFS was statistically significantly improved for gefitinib-treated patients with EGFR FISH-positive tumors.

Determination of Diclofenac sodium by high-performance liquid chromatography in 0,1 % eyedrops

International Nuclear Information System (INIS)

Garcia Penna, Caridad Margarita; Pereda Rodriguez, Diana; Gonzalez Hortezon, Ania; Montes de Oca Porto, Yanet; Cannizares Arencibia, Yanara; Leon Guerrero, Gissel Maria

2009-01-01

Diclofenac sodium is a drug prescribed in eye anterior segment inflammation postoperative treatments, preoperative and postoperative cataract meiosis inhibition, symptomatic treatment of non-infectious chronic conjunctivitis, of ocular inflammation, of ocular pain, and of refractory postsurgical photophobia. In present paper we developed and validated an analytical method by high-performance liquid chromatography to quality control, and stability studies of Diclofenac sodium of 1 % eye drops. Method was based on active principle separation through endcapped 1 00RP-8 Lichrospher chromatographic column (5 μ) (250 x 4 mm) using UV detection to 254 nm, thus using a mobile phase including sodium a solution of hydrogen phosphate to a 2.5 pH: methanol in a 34:60 ratio. Calibration curve was plotted during the interval of 60 to 140 % where it was linear with a correlation coefficient equal to 0.9995; statistic test for interception and slope was considered as non-significant. We achieved a recovery rate of 100.25 % during study concentration interval, and Cochran (G) and Student (t) tests were not significant. Variation coefficient in repeating study was equal to 0.39 % for the 6 assayed replica, whereas in average precision analysis Fischer and Student tests were non-significant. Analytical method was linear, precise, specific and exact during the interval of study concentrations. (Author)

Phase-inversion tape-casting preparation and significant performance enhancement of Ce0.9Gd0.1O1.95- La0.6Sr0.4Co0.2Fe0.8O3-δ dual-phase asymmetric membrane for oxygen separation

DEFF Research Database (Denmark)

Huang, Hua; Cheng, Shiyang; Gao, Jianfeng

2014-01-01

The dual-phase Ce0.9Gd0.1O1.95–La0.6Sr0.4Co0.2Fe0.8O3−δ asymmetric membrane was prepared via a phase-inversion tape-casting method. The membrane consisted of a thicker porous support layer and a thinner dense layer. When the dense side of the membrane was coated with a La0.6Sr0.4CoO3−δ catalytic...

Integrating Tenascin-C protein expression and 1q25 copy number status in pediatric intracranial ependymoma prognostication: A new model for risk stratification.

Science.gov (United States)

Andreiuolo, Felipe; Le Teuff, Gwénaël; Bayar, Mohamed Amine; Kilday, John-Paul; Pietsch, Torsten; von Bueren, André O; Witt, Hendrik; Korshunov, Andrey; Modena, Piergiorgio; Pfister, Stefan M; Pagès, Mélanie; Castel, David; Giangaspero, Felice; Chimelli, Leila; Varlet, Pascale; Rutkowski, Stefan; Frappaz, Didier; Massimino, Maura; Grundy, Richard; Grill, Jacques

2017-01-01

Despite multimodal therapy, prognosis of pediatric intracranial ependymomas remains poor with a 5-year survival rate below 70% and frequent late deaths. This multicentric European study evaluated putative prognostic biomarkers. Tenascin-C (TNC) immunohistochemical expression and copy number status of 1q25 were retained for a pooled analysis of 5 independent cohorts. The prognostic value of TNC and 1q25 on the overall survival (OS) was assessed using a Cox model adjusted to age at diagnosis, tumor location, WHO grade, extent of resection, radiotherapy and stratified by cohort. Stratification on a predictor that did not satisfy the proportional hazards assumption was considered. Model performance was evaluated and an internal-external cross validation was performed. Among complete cases with 5-year median follow-up (n = 470; 131 deaths), TNC and 1q25 gain were significantly associated with age at diagnosis and posterior fossa tumor location. 1q25 status added independent prognostic value for death beyond the classical variables with a hazard ratio (HR) = 2.19 95%CI = [1.29; 3.76] (p = 0.004), while TNC prognostic relation was tumor location-dependent with HR = 2.19 95%CI = [1.29; 3.76] (p = 0.004) in posterior fossa and HR = 0.64 [0.28; 1.48] (p = 0.295) in supratentorial (interaction p value = 0.015). The derived prognostic score identified 3 different robust risk groups. The omission of upfront RT was not associated with OS for good and intermediate prognostic groups while the absence of upfront RT was negatively associated with OS in the poor risk group. Integrated TNC expression and 1q25 status are useful to better stratify patients and to eventually adapt treatment regimens in pediatric intracranial ependymoma.

Integrating Tenascin-C protein expression and 1q25 copy number status in pediatric intracranial ependymoma prognostication: A new model for risk stratification.

Directory of Open Access Journals (Sweden)

Felipe Andreiuolo

Full Text Available Despite multimodal therapy, prognosis of pediatric intracranial ependymomas remains poor with a 5-year survival rate below 70% and frequent late deaths.This multicentric European study evaluated putative prognostic biomarkers. Tenascin-C (TNC immunohistochemical expression and copy number status of 1q25 were retained for a pooled analysis of 5 independent cohorts. The prognostic value of TNC and 1q25 on the overall survival (OS was assessed using a Cox model adjusted to age at diagnosis, tumor location, WHO grade, extent of resection, radiotherapy and stratified by cohort. Stratification on a predictor that did not satisfy the proportional hazards assumption was considered. Model performance was evaluated and an internal-external cross validation was performed.Among complete cases with 5-year median follow-up (n = 470; 131 deaths, TNC and 1q25 gain were significantly associated with age at diagnosis and posterior fossa tumor location. 1q25 status added independent prognostic value for death beyond the classical variables with a hazard ratio (HR = 2.19 95%CI = [1.29; 3.76] (p = 0.004, while TNC prognostic relation was tumor location-dependent with HR = 2.19 95%CI = [1.29; 3.76] (p = 0.004 in posterior fossa and HR = 0.64 [0.28; 1.48] (p = 0.295 in supratentorial (interaction p value = 0.015. The derived prognostic score identified 3 different robust risk groups. The omission of upfront RT was not associated with OS for good and intermediate prognostic groups while the absence of upfront RT was negatively associated with OS in the poor risk group.Integrated TNC expression and 1q25 status are useful to better stratify patients and to eventually adapt treatment regimens in pediatric intracranial ependymoma.

Magnetocaloric response of La 0.70 Ca 0.1 Sr 0.2 Fe 0.1 Mn 0.9 O 3 ...

Indian Academy of Sciences (India)

Home; Journals; Bulletin of Materials Science; Volume 38; Issue 1. Magnetocaloric response of La0.70Ca0.1Sr0.2Fe0.1Mn0.9O3 pervoskite for magnetic refrigeration. M S Anwar Faheem Ahmed Bon Heun Koo. Volume 38 Issue 1 February 2015 pp 101-104 ...

Oxygen permeation in thin, dense Ce0.9Gd0.1O 1.95- membranes II. experimental determination

DEFF Research Database (Denmark)

Chatzichristodoulou, Christodoulos; Søgaard, Martin; Glasscock, Julie

2011-01-01

Thin (∼30 m), dense Ce0.9Gd0.1O1.95- (CGO10) membranes (5 5 cm2+) supported on a porous NiO/YSZ substrate were fabricated by tape casting, wet powder spraying and lamination. A La 0.58Sr0.4Co0.2Fe0.8O 3-δ/Ce0.9Gd0.1O1.95- (LSCF/CGO10) composite cathode was applied by screen printing. Oxygen...... compartment. The performance of the membrane was also investigated under varying CH 4 and H2O gas mixtures at 1106 K. The oxygen flux increased with decreasing steam to carbon ratio and was found to exceed 10 N mL min-1 cm-2 of O2 for steam to carbon ratios below 4:3. Post-test analysis of the tested membrane...

Effect of A-site deficiency in LaMn_0_._9Co_0_._1O_3 perovskites on their catalytic performance for soot combustion

International Nuclear Information System (INIS)

Dinamarca, Robinson; Garcia, Ximena; Jimenez, Romel; Fierro, J.L.G.; Pecchi, Gina

2016-01-01

Highlights: • A-site defective perovskites increases the oxidation state of the B-cation. • Not always non-stoichiometric perovskites exhibit higher catalytic activity in soot combustion. • The highly symmetric cubic crystalline structure diminishes the redox properties of perovskites. - Abstract: The influence of lanthanum stoichiometry in Ag-doped (La_1_-_xAg_xMn_0_._9Co_0_._1O_3) and A-site deficient (La_1_-_xMn_0_._9Co_0_._1O_3_-_δ) perovskites with x equal to 10, 20 and 30 at.% has been investigated in catalysts for soot combustion. The catalysts were prepared by the amorphous citrate method and characterized by XRD, nitrogen adsorption, XPS, O_2-TPD and TPR. The formation of a rhombohedral excess-oxygen perovskite for Ag-doped and a cubic perovskite structure for an A-site deficient series is confirmed. The efficient catalytic performance of the larger Ag-doped perovskite structure is attributed to the rhombohedral crystalline structure, Ag_2O segregated phases and the redox pair Mn"4"+/Mn"3"+. A poor catalytic activity for soot combustion was observed with A-site deficient perovskites, despite the increase in the redox pair Mn"4"+/Mn"3"+, which is attributed to the cubic crystalline structure.

Impact of clinical status and salivary conditions on xerostomia and oral health-related quality of life of adolescents with type 1 diabetes mellitus.

Science.gov (United States)

Busato, Ivana Maria Saes; Ignácio, Sérgio Aparecido; Brancher, João Armando; Moysés, Simone Tetu; Azevedo-Alanis, Luciana Reis

2012-02-01

To investigate the influence of clinical status and salivary conditions on the presence of xerostomia on adolescents with and without type 1 diabetes mellitus (DM1), and further to investigate the influence of clinical status, salivary conditions and xerostomia on oral health-related quality of life (OHQoL) of those with DM1. A cross-sectional study was performed on 102 adolescents, 51 with DM1 and 51 nondiabetics. Xerostomia was detected by asking a question about the sensation of having 'dry mouth', and Oral Health Impact Profile-14 was used to measure the impact of xerostomia on OHQoL. The clinical status was assessed by using decayed, missing or filled and Community Periodontal indices, and by evaluating oral manifestations; and the following salivary conditions were evaluated: stimulated salivary flow, pH, buffer capacity, total protein, amylase, urea, calcium, and glucose salivary concentrations. Multiple logistic regression analysis was used to evaluate the influence of clinical status and salivary conditions on xerostomia and the impact of xerostomia on the OHQoL of adolescents with DM1. Clinical status and salivary conditions was shown to have no influence on the presence of xerostomia. Bivariate (P = 0.00) and logistic regression (P = 0.01) analysis showed a significant association between DM1 and xerostomia. Logistic regression analysis showed association between xerostomia (P = 0.00) and OHQoL, and caries experience (P = 0.03) and OHQoL. DM1 showed to be predictive of a high prevalence of xerostomia in adolescents. Caries experience and xerostomia showed to have a negative impact on the OHQoL of adolescents with DM1. © 2011 John Wiley & Sons A/S.

Predicted energetics and properties of rare-earth ferrites films grown on cubic (1 1 1)- and hexagonal (0 0 0 1)-oriented substrates

International Nuclear Information System (INIS)

Zhao, Hong Jian; Chen, Xiang Ming; Xu, Changsong; Duan, Wenhui; Yang, Yurong; Bellaiche, L

2015-01-01

First-principles calculations are performed to compare the energetics of several phases, including hexagonal polar P6 3 cm and perovskite non-polar Pbnm-like states, of epitaxial RFeO 3 films (with R  =  Ce, Pr, Nd, Sm, Gd, Tb, Dy, Ho, Er and Lu) grown on different cubic (1 1 1)- and hexagonal (0 0 0 1)-oriented substrates. The P6 3 cm phase is found to be the ground state for large enough in-plane lattice parameters in all investigated RFeO 3 films, and its polarization is tunable by the amount of epitaxial strain. Series of available substrates allowing the growth of hexagonal polar RFeO 3 films, as well as other phenomena of fundamental and technological importance (e.g. different ground states and coexistence between several phases) are also predicted. (paper)

Status of the 0+ nonet

International Nuclear Information System (INIS)

Morgan, D.

1975-08-01

The phenomenological case is presented for a complete normal scalar nonet comprising delta(976)(I=1), kappa(1250)(I=1/2), S *(1000) and epsilon('1200') (I=0), non-ideally mixed (thetasub(S)approximately65 0 +-5 0 as against thetasup(Ideal)approximately35 0 ), but seemingly respecting Zweig's Rule in its hadronic decays. These decays, which go almost entirely to two-body S-wave final states, exhibit the inherent kinematic complications in a simple way. This is especially so for the delta and S * systems for each of which the resonance pole occurs just below the threshold of the strongly coupled KantiK channel. In the I-0 system, to which the S * couples, the 'background' itself manifests resonance activity whose classification requires a scheme for describing overlapping resonances. The only natural prescription appears to be that of 'adding phase-shifts' (strictly, multiplying Jost-functions); on applying it to the residual I=0 dynamics the epsilon(900) and epsilon'(1250) effects coalesce into a single broad elastic resonance centred at or above 1100MeV. This completes the tally of nonet candidates to whose hadronic decays a conventional SU(3) analysis is then applied. Some wider bearings of the resulting non-ideal nonet structure are mentioned. (author)

Status of the 0+ nonet

International Nuclear Information System (INIS)

Morgan, D.

1975-01-01

The phenomenological case is presented for a complete normal scalar nonet comprising delta(976) (I = 1), kappa(1250) (I = 1 / 2 ), S*(1000) and epsilon('1200') (I = 0), nonideally mixed (theta/sub S/ approximately 65 0 +- 5 0 as against theta/sup Ideal/ approximately 35 0 ), but seemingly respecting Zweig's rule in its hadronic decays. These decays, which go almost entirely to two-body S-wave final states, exhibit the inherent kinematic complications in a simple way. This is especially so for the delta and S* systems for each of which the resonance pole occurs just below the threshold of the strongly coupled K anti K channel. In the I = 0 system, to which the S* couples, the 'background' itself manifests resonance activity whose classification requires a scheme for describing overlapping resonances. The only natural prescription appears to be that of 'adding phase shifts' (strictly, multiplying Jost-functions); on applying it to the residual I = 0 dynamics the epsilon(900) and epsilon'(1250) effects coalesce into a single broad elastic resonance centered at or above 1100 MeV. This completes the tally of nonet candidates to whose hadronic decays a conventional SU(3) analysis is then applied. Some wider bearings of the resulting nonideal nonet structure are mentioned

Performance and load data from Mod-0A and Mod-1 wind turbine generators

Science.gov (United States)

Spera, D. A.; Janetzke, D. C.

1982-01-01

Experimental data, together with supporting analysis, are presented on the power conversion performance and blade loading of large, horizontal-axis wind turbines tested at electric utility sites in the U.S. Four turbine rotor configurations, from 28 to 61 meters in diameter, and data from five test sites are included. Performance data are presented in the form of graphs of power and system efficiency versus free-stream wind speed. Deviations from theoretical performance are analyzed statistically. Power conversion efficiency averaged 0.34 for all tests combined, compared with 0.31 predicted. Round blade tips appeared to improve performance significantly. Cyclic blade loads were normalized to develop load factors which can be used in the design of rotors with rigid hubs.

FEEDING PATTERN TOWARD THE INCREASING OF NUTRITIONAL STATUS IN CHILDREN AGED 1–3 YEARS

Directory of Open Access Journals (Sweden)

Toni Subarkah

2017-02-01

Full Text Available Introduction: The prevalence of nutritional status problems with underweight in Indonesia at the moments is (19,6%. Data showed that children with less nutritional status aged 1-3 years in Kalijudan, Surabaya are existed. Provide feeding pattern properly is one effort to improve the nutritional status by fulfilling the needs of the child nutrition. The purpose of this study was to explain the relationship of feeding pattern and nutritional status in children aged 1-3 years in the Kalijudan district, Surabaya. Methods: The research design used was cross-sectional study with dietary habit as the independent variable and nutritional status as dependent variable. The sample was taken from 154 mothers and children. Consecutive sampling was deployed. Data collection by questionnaires, and then data analysis using the Spearman’s Rho in level  of significance α≤0.05. Result and Analysis: There was strong relationship between feeding pattern and nutritional status (r=0.640. The result showed that inappropriate feeding patterns with nutritional status is very thin (44.4% a proper feeding patterns with normal nutritional status (89.7%.  Discussion and Conclussion: The efforts to improve nutritional status of children aged 1-3 years related to feeding patterns should be improved in order to achieve a normal nutritional status. Further research may explore on the feeding patterns based on dietary allowances. Keywords: feeding pattern, nutritional status, 1-3 years old children

Synthesis of porous LiFe0.2Mn1.8O4 with high performance for lithium-ion battery

International Nuclear Information System (INIS)

Shi, Yishan; Zhu, Shenmin; Zhu, Chengling; Li, Yao; Chen, Zhixin; Zhang, Di

2015-01-01

Highlights: • Porous LiFe 0.2 Mn 1.8 O 4 was fabricated with P123 as a template through a nitrate decomposition method • A high rate capacity and cycling stability were demonstrated when used as cathode in LIBs • This strategy is expected to fabricate other multiple metal oxides with porous structures - Abstract: A facile and effective route was developed for the fabrication of LiFe 0.2 Mn 1.8 O 4 with porous structures by using Pluronic P-123 as a soft template, based on a nitrate decomposition method. The resultant LiFe 0.2 Mn 1.8 O 4 was characterized by XRD, SEM, as well as N 2 adsorption/desorption measurements which showed a porous structure with a pore size centered at 20 nm. When used as cathode materials in lithium battery, the as-synthesized LiFe 0.2 Mn 1.8 O 4 exhibited a discharge capacity of 122 mAh g −1 at 1 C and 102 mAh g −1 at 5 C. Moreover, after 500 cycles, the capacity retention (108 mAh g −1 ) reached 88% of the initial capacity at 1 C. As compared with conventional cathode LiMn 2 O 4 , the high performance is believed to originate from the combined effects of porous structure, iron doping and highly crystalline nature of the obtained LiFe 0.2 Mn 1.8 O 4 . This strategy is expected to allow the fabrication of other multiple metal oxides with porous structures for high performance cathode materials

The 140 GHZ, 1 MW Gyrotron - Status and Recent Results

Science.gov (United States)

Gantenbein, G.; Dammertz, G.; Illy, S.; Kern, S.; Leonhardt, W.; Piosczyk, B.; Schmid, M.; Thumm, M.; Braune, H.; Erckmann, V.; Laqua, H. P.; Michel, G.; Kasparek, W.; Lechte, C.; Legrand, F.; Lievin, C.; Prinz, O.

2009-04-01

A 10 MW ECRH system is currently under construction for the stellarator W7-X which will be built up and operated by IPP in Greifswald, Germany. The present status of the complete system is reported in [1]. The RF power will be provided by 10 gyrotrons. A European collaboration has been established to develop and build the 10 gyrotrons each with an output power of 1 MW for continuous wave (CW) operation [2]. Nine gyrotrons are being manufactured by Thales Electron Devices (TED), Vélizy, France, one gyrotron was produced by CPI, Palo Alto, CA and passed the acceptance tests at IPP. The acceptance tests of the TED gyrotrons are performed at the test stand at FZK and on site at IPP. The first series tube yielded a total output power of 0.98 MW, with an efficiency of 31 % (without a single stage depressed collector) in short pulse operation and of 0.92 MW in pulses of 1800 s (efficiency of almost 45 % at a depression voltage of 29 kV) [3], The Gaussian mode output power was 0.91 MW. The RF power, measured in a calorimetric load at the end of a 25 m long quasi-optical transmission line with seven mirrors, was 0.87 MW. In this contribution typical results of the next series gyrotrons will be reported.

High performance and highly durable infiltrated cathodes using Pr-modified Ce_0.9Gd_0.1O_1.95 backbone

DEFF Research Database (Denmark)

Samson, Alfred Junio; Søgaard, Martin; Bonanos, Nikolaos

2014-01-01

°C (without Pr: Rp from 0.094 to 0.45 Ω cm2, Rs from 0.74 to 0.79 Ω cm2; with Pr: Rp from 0.051 to 0.32 Ω cm2, Rs from 0.74 to 0.71 Ω cm2). The improved performance and heat treatment tolerance is thought to originate from the imparted electronic conductivity into the CGO backbone by introducing Pr....

Annual Status Report (FY2016) Performance Assessment for the Environmental Restoration Disposal Facility

Energy Technology Data Exchange (ETDEWEB)

Casbon, M. A. [CH2M HILL Plateau Remediation Company, Richland, WA (United States); Nichols, W. E. [CH2M HILL Plateau Remediation Company, Richland, WA (United States)

2017-03-15

DOE O 435.1, Radioactive Waste Management, and DOE M 435.1-1, Radioactive Waste Management Manual, require that a determination of continued adequacy of the performance assessment (PA), composite analysis (CA), and disposal authorization statement (DAS) be made on an annual basis, and it must consider the results of data collection and analysis from research, field studies, and monitoring. Annual summaries of low-level waste (LLW) disposal operations must be prepared with respect to the conclusions and recommendations of the PA and CA, and a determination of the need to revise the PA or CA must be made. The annual summary requirement provides a structured approach for demonstrating the continued adequacy of the PA and CA in demonstrating a reasonable expectation that the performance objectives will be met. This annual summary addresses only the status of the Environmental Restoration Disposal Facility (ERDF) PA (CP-60089, Performance Assessment for the Environmental Restoration Disposal Facility, Hanford Site, Washington, formerly WCH-520 Rev. 1)1. The CA for ERDF is supported by DOE/RL-2016-62, Annual Status Report (FY 2016): Composite Analysis of Low Level Waste Disposal in the Central Plateau at the Hanford Site. The ERDF PA portion of the CA document is found in Section 3.1.4, and the ERDF operations portion is found in Section 3.3.3.2 of that document.

Performance of Mg-14Li-1Al-0.1Ce as anode for Mg-air battery

Energy Technology Data Exchange (ETDEWEB)

Ma, Yibin; Li, Deyu [School of Chemical Engineering and Technology, Harbin Institute of Technology, West Street No. 92, Harbin 150001 (China); Li, Ning [School of Chemical Engineering and Technology, Harbin Institute of Technology, West Street No. 92, Harbin 150001 (China); Key Laboratory of Superlight Materials and Surface Technology, Ministry of Education, Harbin Engineering University, Harbin 150001 (China); Zhang, Milin; Huang, Xiaomei [Key Laboratory of Superlight Materials and Surface Technology, Ministry of Education, Harbin Engineering University, Harbin 150001 (China)

2011-02-15

In this research, a new Mg-air battery based on Mg-14Li-1Al-0.1Ce was prepared and the battery performance was investigated by constant current discharge test. The corrosion behavior of Mg, AZ31 and Mg-Li-Al-Ce were studied by self-corrosion rate measurement and potentiodynamic polarization measurement. The characteristics of Mg-Li-Al-Ce after discharge were investigated by electrochemical impedance spectroscopy (EIS), scanning electron microscopy (SEM) and X-ray diffraction (XRD). The results show that Mg-Li-Al-Ce is more active than Mg and AZ31. The self-corrosion rate is found to be in the order: Mg-Li-Al-Ce < Mg < AZ31. It has been observed that the Mg-air battery based on Mg-Li-Al-Ce offers higher operating voltage, anodic efficiency and capacity than those with Mg and AZ31. SEM and EIS results show that the discharge product of Mg-Li-Al-Ce is loosely adhered to the alloy surface, and thus Mg-Li-Al-Ce could keep high discharge activity during discharge. (author)

Polarity driven morphology of CeO2(1 0 0) islands on Cu(1 1 1)

International Nuclear Information System (INIS)

Stetsovych, O.; Beran, J.; Dvořák, F.; Mašek, K.; Mysliveček, J.; Matolín, V.

2013-01-01

Thin ceria films supported by metal substrates represent important model systems for reactivity studies in heterogeneous catalysis. Here we report the growth study of the polar CeO 2 (1 0 0) phase as part of a mixed CeO 2 (1 1 1)–CeO 2 (1 0 0) thin film supported by Cu(1 1 1). The two ceria phases grow on different areas of the substrate, what allows a reliable growth characterization of the CeO 2 (1 0 0) islands on Cu(1 1 1). Scanning tunneling microscopy measurements reveal CeO 2 (1 0 0) to grow in the form of highly dispersed three dimensional (3D) islands on a CeO 2 (1 0 0) interfacial layer. The CeO 2 (1 0 0) islands exhibit a 2 × 2 surface reconstruction. The presence of the surface reconstruction together with the highly dispersed growth of CeO 2 (1 0 0) islands corresponds to the requirement for compensation of the surface dipole moment on the CeO 2 (1 0 0). CeO 2 (1 0 0) islands are further characterized by reflection high energy electron diffraction yielding their epitaxial relations with respect to the Cu(1 1 1) substrate. The growth of well characterized CeO 2 (1 0 0) islands supported by Cu(1 1 1) represents a starting point for developing a novel template for structure-related reactivity studies of ceria based model catalysts.

Randomized Phase II Study of Gefitinib Compared With Placebo in Chemotherapy-Naive Patients With Advanced Non–Small-Cell Lung Cancer and Poor Performance Status

Science.gov (United States)

Goss, Glenwood; Ferry, David; Wierzbicki, Rafal; Laurie, Scott A.; Thompson, Joyce; Biesma, Bonne; Hirsch, Fred R.; Varella-Garcia, Marileila; Duffield, Emma; Ataman, Ozlem U.; Zarenda, Marc; Armour, Alison A.

2009-01-01

Purpose To compare gefitinib with placebo in chemotherapy naïve patients with advanced non–small-cell lung cancer (NSCLC) and poor performance status. Patients and Methods NSCLC patients (chemotherapy naïve, WHO performance status 2 or 3; unfit for chemotherapy; stage IIIB/IV) were randomly assigned to gefitinib (250 mg/d) plus best supportive care (BSC; n = 100) or placebo plus BSC (n = 101). The primary end point was progression-free survival (PFS). Secondary end points included overall survival (OS), objective response rate (ORR), quality of life (QOL), pulmonary symptom improvement (PSI), and safety. Correlation of gefitinib efficacy with EGFR gene copy number (fluorescent in situ hybridization [FISH]) was explored. Results Hazard ratios (HRs; gefitinib:placebo) were 0.82 (95% CI, 0.60 to 1.12; P = .217) for PFS and 0.84 (95% CI, 0.62 to 1.15; P = .272) for OS. As expected for this patient population, OS for both arms was poor, at about 3 months. ORRs were 6.0% (gefitinib) and 1.0% (placebo). QOL and PSI rates were 21.1% and 28.3% (gefitinib) and 20.0% and 28.3% (placebo), respectively. In EGFR FISH-positive patients (n = 32), HRs were 0.29 (95% CI, 0.11 to 0.73) for PFS and 0.44 (95% CI, 0.17 to 1.12) for OS. No unexpected adverse events occurred. Conclusion There was no statistically significant difference in PFS, OS, and ORRs after treatment with gefitinib or placebo, in the overall population; improvements in QOL and symptoms were similar in both groups. Tolerability profile of gefitinib was consistent with previous studies. PFS was statistically significantly improved for gefitinib-treated patients with EGFR FISH-positive tumors. PMID:19289623

Reproductive performance and nutritional status of Holstein cows in Brazil

International Nuclear Information System (INIS)

Meirelles, C.F.; Vitti, D.M.S.S.; Abdalla, A.L.

1990-01-01

Reproductive performance and nutritional status were assessed in Holstein cows from two dairy herds in Sao Paulo State, Brazil. In the first herd (good management, G), concentrate was fed individually to cows, complete records were kept, veterinary services were provided as necessary and the standard of husbandry practices was good. In the second herd (fair management, F), veterinary services were used only occasionally, the concentrate fed was divided equally among lactating cows and the standard of husbandry practices was only fair. Haemoglobin, haematocrit, glucose, total protein and phosphorus were measured in blood collected at various times after calving. There were no statistical differences between the blood parameters in the two herds except for inorganic phosphorus which differed significantly between farms (P < 0.01). Only plasma glucose had a significant (P < 0.01) effect on the time required by the animals to initiate post-partum ovarian activity. The proportion of cows ovulating by day 60 was 75% in herd G versus 53% in herd F (P < 0.01); by day 100 the values were 82% in herd G and 70% in herd F (P < 0.01). Calving intervals were 12.7 and 13.2 months for herds G and F respectively, suggesting comparable reproductive efficiency. However, only 1 of the 28 cows in herd G was open more than 365 days after calving, as opposed to 5 of the 30 cows in herd F. When a value of 365 open days was given for these non-pregnant cows, the average days open for the herds were then 123 and 154 days for herds G and F respectively, indicating a decided production advantage in favour of the better managed herd. (author). 16 refs, 1 fig., 2 tabs

Comparison of an inflammation-based prognostic score (GPS) with performance status (ECOG-ps) in patients receiving palliative chemotherapy for gastroesophageal cancer.

Science.gov (United States)

Crumley, Andrew B C; Stuart, Robert C; McKernan, Margaret; McDonald, Alexander C; McMillan, Donald C

2008-08-01

The aim of the present study was to compare an inflammation-based prognostic score (Glasgow Prognostic Score, GPS) with performance status (ECOG-ps) in patients receiving platinum-based chemotherapy for palliation of gastroesophageal cancer. Sixty-five patients presenting with gastroesophageal carcinoma to the Royal Infirmary, Glasgow between January 1999 and December 2005 and who received palliative chemotherapy or chemo-radiotherapy were studied. ECOG-ps, C-reactive protein, and albumin were recorded at diagnosis. Patients with both an elevated C-reactive protein (>10 mg/L) and hypoalbuminemia (L) were allocated a GPS of 2. Patients in whom only one of these biochemical abnormalities was present were allocated a GPS of 1 and patients with a normal C-reactive protein and albumin were allocated a score of 0. Toxicity was recorded using the Common Toxicity Criteria. The minimum follow up was 14 months. During the follow-up period, 59 (91%) of the patients died. On univariate and multivariate survival analysis, only the GPS (hazard ratios 1.65, 95% CI 1.10-2.47, P GPS of 0, those patients with a GPS of 1 or 2 required more frequent chemotherapy dose reduction (P GPS, appears to be superior to the subjective assessment of performance status (ECOG-ps) in predicting the response to platinum-based chemotherapy in patients with advanced gastroesophageal cancer.

Predicting employment status and subjective quality of life in patients with schizophrenia

Directory of Open Access Journals (Sweden)

Haruo Fujino

2016-03-01

Full Text Available Although impaired social functioning, particularly poor employment status, is a cardinal feature of patients with schizophrenia and leads to decreased quality of life (QOL, few studies have addressed the relationship between these two clinical issues. The aim of this study was to determine whether employment status predicts subjective QOL and to evaluate a model in which functional capacity mediates the relationship between general cognitive performance and employment status. Ninety-three patients with schizophrenia were administered a comprehensive battery of cognitive tests, the UCSD Performance-based Skills Assessment-Brief version (UPSA-B, the Social Functioning Scale (SFS, and the Subjective Quality of Life Scale (SQLS. First, we evaluated a model for predicting the employment/occupation subscale score of the SFS using path analysis, and the model fitted well (χ2 (4 = 3.6, p = 0.46; CFI = 1.0; RMSEA < 0.001, with 90% CIs: 0–0.152. Employment status was predicted by negative symptoms and functional capacity, which was in turn predicted by general cognitive performance. Second, we added subjective QOL to this model. In a final path model, QOL was predicted by negative symptoms and employment status. This model also satisfied good fit criteria (χ2 (7 = 10.3, p = 0.17; CFI = 0.987; RMSEA = 0.072, with 90% CIs: 0–0.159. The UPSA-B and SFS scores were moderately correlated with most measures of cognitive performance. These results support the notion that better employment status enhances subjective QOL in patients with schizophrenia.

Status and performance of PF injector linac

International Nuclear Information System (INIS)

Sato, Isamu

1994-01-01

PF injector linac has been improved on a buncher section for accelerating of intense electron beam, and reinforced a focusing system of the positron generator linac for the expansion of phase space. In this presentation, I shall report present status and performance of PF injector linac, and discuss its upgrade program for B-factory project. (author)

PHASE EVOLUTION AND MICROWAVE DIELECTRIC PROPERTIES OF (Li0.5Bi0.5)(W1-xMox)O4(0.0 ≤ x ≤ 1.0) CERAMICS WITH ULTRA-LOW SINTERING TEMPERATURES

Science.gov (United States)

Zhou, Di; Guo, Jing; Yao, Xi; Pang, Li-Xia; Qi, Ze-Ming; Shao, Tao

2012-11-01

The (Li0.5Bi0.5)(W1-xMox)O4(0.0 ≤ x ≤ 1.0) ceramics were prepared via the solid state reaction method. The sintering temperature decreased almost linearly from 755°C for (Li0.5Bi0.5)WO4 to 560°C for (Li0.5Bi0.5)MoO4. When the x≤0.3, a wolframite solid solution can be formed. For x = 0.4 and x = 0.6 compositions, both the wolframite and scheelite phases can be formed from the X-ray diffraction analysis, while two different kinds of grains can be revealed from the scanning electron microscopy and energy-dispersive X-ray spectrometer results. High performance of microwave dielectric properties were obtained in the (Li0.5Bi0.5)(W0.6Mo0.4)O4 ceramic sintered at 620°C with a relative permittivity of 31.5, a Qf value of 8500 GHz (at 8.2 GHz), and a temperature coefficient value of +20 ppm/°C. Complex dielectric spectra of pure (Li0.5Bi0.5)WO4 ceramic gained from the infrared spectra were extrapolated down to microwave range, and they were in good agreement with the measured values. The (Li0.5Bi0.5)(W1-xMox)O4(0.0 ≤ x ≤ 1.0) ceramics might be promising for low temperature co-fired ceramic technology.

Correlation between nutritional status and comprehensive physical performance measures among older adults with undernourishment in residential institutions

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Singh DKA

2014-08-01

Full Text Available Devinder KA Singh,1 Zahara A Manaf,2 Noor Aini M Yusoff,3 Nur A Muhammad,2 Mei Fang Phan,1 Suzana Shahar2 1Physiotherapy Program, School of Rehabilitation Sciences, 2Nutrition and Dietetics Program, School of Health Care Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, 3ASIA Metropolitan University, Cheras, Malaysia Purpose: The consequences of combined undernourishment and decreased physical ­performance in older adults are debilitating and increases cost of care. To date, the information regarding the association between nutritional status and physical performance does not provide a complete picture. Most studies used limited or self-reported measures to evaluate physical performance. The objective of this study was to examine the correlation between nutritional status and comprehensive physical performance measures among undernourished older adults who reside in residential institutions.Methods: Forty-seven older adults (26 males, 21 females aged ≥60 (69.23±8.63 years who were identified as undernourished from two residential institutions participated in this study. A battery of physical performance tests (10 m gait speed test, dominant hand grip strength test, timed five-repetition sit-to-stand test, ten step test, arm curl test, scratch test, and respiratory muscle strength test, biochemical profiles (serum albumin, hemoglobin, serum ferritin, and prealbumin levels, and falls risk using the short-form Physiological Profile Approach were performed. The Functional Ability Questionnaire and Geriatric Depression Scale were also administered.Results: The results demonstrated that generally older adults with undernourishment scored poorly on the physical performance tests, had depression, and a high risk of falls. Biochemical results demonstrated that 10.9% of the participants were anemic, 63% had hypoalbuminemia (<3.5 g/dL, and 21.7% were at risk of protein energy malnutrition with prealbumin level (100–170 mg/L. A significant

GStat 2.0: Grid Information System Status Monitoring

International Nuclear Information System (INIS)

Field, Laurence; Huang, Joanna; Tsai, Min

2010-01-01

Grid Information Systems are mission-critical components in today's production grid infrastructures. They enable users, applications and services to discover which services exist in the infrastructure and further information about the service structure and state. It is therefore important that the information system components themselves are functioning correctly and that the information content is reliable. Grid Status (GStat) is a tool that monitors the structural integrity of the EGEE information system, which is a hierarchical system built out of more than 260 site-level and approximately 70 global aggregation services. It also checks the information content and presents summary and history displays for Grid Operators and System Administrators. A major new version, GStat 2.0, aims to build on the production experience of GStat and provides additional functionality, which enables it to be extended and combined with other tools. This paper describes the new architecture used for GStat 2.0 and how it can be used at all levels to help provide a reliable information system.

Is the technical performance of young soccer players influenced by hormonal status, sexual maturity, anthropometric profile, and physical performance?

Science.gov (United States)

Moreira, Alexandre; Massa, Marcelo; Thiengo, Carlos R; Rodrigues Lopes, Rafael Alan; Lima, Marcelo R; Vaeyens, Roel; Barbosa, Wesley P; Aoki, Marcelo S

2017-12-01

The aim of this study was to examine the influence of hormonal status, anthropometric profile, sexual maturity level, and physical performance on the technical abilities of 40 young male soccer players during small-sided games (SSGs). Anthropometric profiling, saliva sampling, sexual maturity assessment (Tanner scale), and physical performance tests (Yo-Yo and vertical jumps) were conducted two weeks prior to the SSGs. Salivary testosterone was determined by the enzyme-linked immunosorbent assay method. Technical performance was determined by the frequency of actions during SSGs. Principal component analyses identified four technical actions of importance: total number of passes, effectiveness, goal attempts, and total tackles. A multivariate canonical correlation analysis was then employed to verify the prediction of a multiple dependent variables set (composed of four technical actions) from an independent set of variables, composed of testosterone concentration, stage of pubic hair and genitalia development, vertical jumps and Yo-Yo performance. A moderate-to-large relationship between the technical performance set and the independent set was observed. The canonical correlation was 0.75 with a canonical R 2 of 0.45. The highest structure coefficient in the technical performance set was observed for tackles (0.77), while testosterone presented the highest structure coefficient (0.75) for the variables of the independent set. The current data suggest that the selected independent set of variables might be useful in predicting SSG performance in young soccer players. Coaches should be aware that physical development plays a key role in technical performance to avoid decision-making mistakes during the selection of young players.

The effect of pre-exercise ingestion of corinthian currant on endurance performance and blood redox status.

Science.gov (United States)

Deli, Chariklia K; Poulios, Athanasios; Georgakouli, Kalliopi; Papanikolaou, Konstantinos; Papoutsis, Alexandros; Selemekou, Maria; Karathanos, Vaios T; Draganidis, Dimitris; Tsiokanos, Athanasios; Koutedakis, Yiannis; Fatouros, Ioannis G; Jamurtas, Athanasios Z

2018-02-22

The present study investigated the effect of Corinthian currant pre-exercise supplementation on metabolism, performance and blood redox status during, and after prolonged exercise. Eleven healthy participants (21-45y) performed a 90-min constant-intensity (60-70% VO 2max ) submaximal-trial, plus a time-trial (TT) to exhaustion (95% VO 2max ) after consuming an isocaloric (1.5g CHO/kg BM) amount of randomly assigned Corinthian currant or glucose-drink, or water (control). Blood was drawn at baseline, pre-exercise, 30min, 60min, 90min of submaximal-trial, post-TT, and 1h post-TT. Post-ingestion blood glucose (GLU) under Corinthian currant was higher compared with water, and similar compared with glucose-drink throughout the study. Respiratory quotient under Corinthian currant was similar with glucose-drink and higher than water throughout the submaximal trial. Accordingly, higher CHO and lower fat oxidation were observed under Corinthian currant compared with water. The TT performance was similar between Corinthian currant, glucose-drink and water. Redox status were similar under all three conditions. Reduced glutathione (GSH) declined while total antioxidant capacity (TAC) and uric acid increased during exercise. GSH and TAC returned to baseline, while uric acid remained increased the following 1h. Corinthian currant, although did not alter exercise-mediated redox status changes and performance, was equally effective to a glucose-drink in maintaining GLU levels during prolonged cycling.

Photoemission study of absorption mechanisms in Bi2.0Sr1.8Ca0.8La0.3Cu2.1O8+δ, BaBiO3, and Nd1.85Ce0.15CuO4

International Nuclear Information System (INIS)

Lindberg, P.A.P.; Shen, Z.; Wells, B.O.; Dessau, D.S.; Ellis, W.P.; Borg, A.; Kang, J.; Mitzi, D.B.; Lindau, I.

1989-01-01

Photoemission measurements in the constant-final-state (absorption) mode were performed on three different classes of high-temperature superconductors Bi 2.0 Sr 1.8 Ca 0.8 La 0.3 Cu 2.1 O 8+δ , BaBiO 3 , and Nd 1.85 Ce 0.15 CuO 4 using synchrotron radiation from 20 to 200 eV. Absorption signals from all elements but Ce are identified. The results firmly show that the Bi 6s electrons are more delocalized in BaBiO 3 than in Bi 2.0 Sr 1.8 Ca 0.8 La 0.3 Cu 2.1 O 8+δ , in agreement with the results of band-structure calculations. Differences in the absorption signals due to O and Bi excitations between BaBiO 3 and Bi 2.0 Sr 1.8 Ca 0.8 La 0.3 Cu 2.1 O 8+δ are discussed. Delayed absorption onsets attributed to giant resonances (Ba 4d→4f, La 4d→4f, and Nd 4d→4f transitions) are also reported

Synthesis of 0.3Li2MnO3·0.7LiNi1/3Co1/3Mn1/3O2 cathode materials using 3-D urchin-like MnO2 as precursor for high performance lithium ion battery

International Nuclear Information System (INIS)

Zhao, Chenhao; Hu, Zhibiao; Zhou, Yunlong; Fang, Shuzhen; Cai, Shaohan

2015-01-01

In the paper, we report synthesis of lithium rich layered oxide 0.3Li 2 MnO 3 ·0.7LiNi 1/3 Co 1/3 Mn 1/3 O 2 by using an urchin-like MnO 2 as precursor. The influences of calcination temperatures on the structures and electrochemical performances of as-prepared materials are systematically studied. The results show that the obtained sample can partially retain the morphology of urchin-like precursor especially at low temperature, and a higher calcination temperature helps to improve the layered structure and particle size. As lithium ion battery cathodes, the 750 °C sample with the size of 100–200 nm reveals an optimal electrochemical performance. The initial discharge capacity of 234.6 mAh g −1 with high Coulombic efficiency of 84.6 % can be reached at 0.1C within 2.0–4.7 V. After 50 cycles, the capacity retention can reach 90.2 % at 0.5C. Even at high current density of 5C, the sample also shows a stable discharge capacity of 120.5 mAh g −1 . Anyways, the urchin-like MnO 2 directed route is suitable to prepare 0.3Li 2 MnO 3 ·0.7LiNi 1/3 Co 1/3 Mn 1/3 O 2 as lithium ion battery cathode

8 CFR 209.1 - Adjustment of status of refugees.

Science.gov (United States)

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Adjustment of status of refugees. 209.1... STATUS OF REFUGEES AND ALIENS GRANTED ASYLUM § 209.1 Adjustment of status of refugees. The provisions of this section shall provide the sole and exclusive procedure for adjustment of status by a refugee...

Food provisioning and parental status in songbirds: can occupancy models be used to estimate nesting performance?

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Aude Catherine Corbani

Full Text Available Indirect methods to estimate parental status, such as the observation of parental provisioning, have been problematic due to potential biases associated with imperfect detection. We developed a method to evaluate parental status based on a novel combination of parental provisioning observations and hierarchical modeling. In the summers of 2009 to 2011, we surveyed 393 sites, each on three to four consecutive days at Forêt Montmorency, Québec, Canada. We assessed parental status of 2331 adult songbirds based on parental food provisioning. To account for imperfect detection of parental status, we applied MacKenzie et al.'s (2002 two-state hierarchical model to obtain unbiased estimates of the proportion of sites with successfully nesting birds, and the proportion of adults with offspring. To obtain an independent evaluation of detection probability, we monitored 16 active nests in 2010 and conducted parental provisioning observations away from them. The probability of detecting food provisioning was 0.31 when using nest monitoring, a value within the 0.11 to 0.38 range that was estimated by two-state models. The proportion of adults or sites with broods approached 0.90 and varied depending on date during the sampling season and year, exemplifying the role of eastern boreal forests as highly productive nesting grounds for songbirds. This study offers a simple and effective sampling design for studying avian reproductive performance that could be implemented in national surveys such as breeding bird atlases.

Comparison of the Roche COBAS AmpliPrep/COBAS TaqMan HIV-1 test v1.0 with v2.0 in HIV-1 viral load quantification

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Yi-Ching Tung

2015-04-01

Full Text Available Roche modified the COBAS AmpliPrep/COBAS TaqMan human immunodeficiency virus type 1 (HIV-1 test version 1.0 (CAP/CTM v1.0, resulting in the COBAS AmpliPrep/COBAS TaqMan HIV-1 test version 2.0 (CAP/CTM v2.0. The aim of this study was to evaluate the performance of the CAP/CTM v2.0 and to compare this performance with that of the CAP/CTM v1.0. The study was conducted in a small local study group in Kaohsiung Medical University Hospital, Kaohsiung, Taiwan. A total of 86 plasma samples from HIV-1-seropositive patients were tested using the two assays. The correlation and concordance of results between the two assays were calculated. The CAP/CTM v2.0 generated higher values than did the CAP/CTM v1.0, and five samples (5.8% yielded a difference of > 1 log10 copies/mL. In addition, our data show that CAP/CTM v1.0 and CAP/CTM v2.0 yielded relatively consistent values for 23 samples with low viral loads (< 200 copies/mL. Furthermore, when viral loads were in a medium range (2–5 log10 copies/mL, the results of the two assays were more compatible. This study shows a good correlation between CAP/CTM v1.0 and v2.0 in HIV-1 viral load measurement. Further attention must be paid to those cases in which measured viral loads present larger differences between the two assays.

Status of HLT1 sequence and path towards 30 MHz

CERN Document Server

De Cian, Michel; Gligorov, Vladimir; Hasse, Christoph; Hulsbergen, Wouter; Latham, Thomas Edward; Ponce, Sebastien; Quagliani, Renato; Schreiner, Henry Fredrick; Stemmle, Simon Benedikt; Van Tilburg, Jeroen; Zdybal, Milosz Jerzy; Williams, J Michael

2018-01-01

We present the current status of the HLT1 reconstruction sequence for the LHCb upgrade, both in terms of the number of events which can be processed per second and the achievable physics performance on a selected range of benchmark modes. We present detailed profiling of the various algorithms, describe the bottlenecks, and outline a strategy towards an HLT1 able to process the LHCb upgrade data at 30 MHz

Frequency-modulation transient absorption spectrum of the HCCl A 1A double-prime(0,0,0)left-arrow X 1A'(0,0,0) transition

International Nuclear Information System (INIS)

Chang, B.; Sears, T.J.

1995-01-01

The rotationally resolved spectrum of the HCCl A 1 A double-prime(0,0,0)left-arrow X 1 A'(0,0,0) transition between 12 230 and 12 410 cm -1 was obtained for the first time at Doppler-limited resolution using a frequency-modulation (FM) transient absorption technique. Five major subbands (K a =0 left-arrow 1, 1 left-arrow 0, 1 left-arrow 2, 2 left-arrow 1, and 2 left-arrow 3) of HC 35 Cl and one subband (K a =0 left-arrow 1) of HC 37 Cl were observed and assigned. In addition, the forbidden subband (K a =0 left-arrow 0) of HC 35 Cl was also observed. Thus far, we have assigned most (more than 70%) of the strong lines. The analysis of these subbands determines the geometry for the HCCl A(0,0,0) level: angle HCCl=134.7 degree and R C-Cl =1.623 A while R C-H is fixed at the corresponding value of CH 2 . The height of the barrier to linearity was found to be approximately 2170 cm -1 above the vibrationless level of the A state. The rotational structure of this spectrum shows irregular perturbations. Both random and J-dependent (anomalous K-type doubling) effects were observed. As in methylene, the perturbations most likely arise from Renner--Teller effect between the two singlet states in combination with spin--orbit coupling between the singlet and triplet states

Crystal structure and magnetic properties of La{sub 2−x}(Sr{sub 0.5}Ca{sub 0.5}){sub 1+x}Mn{sub 2}O{sub 7} (x=0.6, 0.8 and 1.0) Ruddlesden–Popper manganites

Energy Technology Data Exchange (ETDEWEB)

Raju, K.; Song, M.S.; Lee, J.Y., E-mail: jylee@yu.ac.kr

2014-05-01

Double layer perovskite (Ruddlesden–Popper) manganites with the nominal composition of La{sub 2−x}(Sr{sub 0.5}Ca{sub 0.5}){sub 1+x}Mn{sub 2}O{sub 7} (x=0.6, 0.8 and 1.0) were synthesized via a solid state reaction route. X-ray and neutron diffraction were performed at room temperature and the crystal structure was refined using the Rietveld method based on the space group, I4/mmm. The temperature variation of the susceptibility revealed a spin glass transition at 28 K for x=0.6, a charge ordering transition at 245 K and a Neel transition at 170 K for x=1.0. - Highlights: • Lanthanum based double layered manganites were prepared by doping with the same amounts of Sr and Ca. • X-ray and neutron diffraction were performed and the crystal structure was refined using the Rietveld method. • Different magnetic transitions were observed depending upon the doping concentration. • Qualitative explanation for the various observed phenomena was given.

Functional performance, nutritional status, and body composition in ambulant community-dwelling individuals 1-3 years after suffering from a cerebral infarction or intracerebral bleeding.

Science.gov (United States)

Vahlberg, Birgit; Zetterberg, Lena; Lindmark, Birgitta; Hellström, Karin; Cederholm, Tommy

2016-02-19

Muscle wasting and obesity may complicate the post-stroke trajectory. We investigated the relationships between nutritional status, body composition, and mobility one to 3 years after stroke. Among 279 eligible home-dwelling individuals who had suffered a stroke (except for subarachnoid bleeding) 1-3 years earlier, 134 (74 ± 5 years, 69% men) were examined according to the Mini Nutritional Assessment-Short Form (MNA-SF, 0-14 points), including body mass index (BMI, kg/m(2)), body composition by bio-impedance analyses (Tanita BC-545), the Short Physical Performance Battery (SPPB, 0-12 points) combining walking speed, balance, and chair stand capacity, and the self-reported Physical Activity Scale for the Elderly (PASE). BMI ≥ 30 kg/m(2) was observed in 22% of cases, and 14% were at risk for malnutrition according to the MNA-SF. SPPB scores ≤ 8 in 28% of cases indicated high risk for disability. Mobility based on the SPPB was not associated with the fat-free mass index (FFMI) or fat mass index (FMI). Multivariate logistic regression indicated that low mobility, i.e., SPPB ≤ 8 points, was independently related to risk for malnutrition (OR 4.3, CI 1.7-10.5, P = 0.02), low physical activity (PASE) (OR 6.5, CI 2.0-21.2, P = 0.02), and high age (OR 0.36, CI 0.15-0.85, P = 0.02). Sarcopenia, defined as a reduced FFMI combined with SPPB scores ≤ 8 or reduced gait speed (sarcopenia with BMI > 30 kg/m(2). Nutritional disorders, i.e., obesity, sarcopenia, or risk for malnutrition, were observed in about one-third of individuals 1 year after stroke. Risk for malnutrition, self-reported physical activity, and age were related to mobility (SPPB), whereas fat-free mass (FFM) and fat mass (FM) were not. Nutrition and exercise treatment could be further evaluated as rehabilitation opportunities after stroke.

Nutritional Status and Cognitive Performance among Children Aged ...

African Journals Online (AJOL)

Without adequate nutrition, children cannot develop to their full physical and mental potentials. The nutritional status and the cognitive performance of 500 school children aged 5-12 years from urban and rural areas of Enugu State, Nigeria were evaluated. Anthropometric measurements of heights and weights were ...

Use of radioimmunoassay techniques to study the effects of nutritional status and breed on reproductive performance of goats

Energy Technology Data Exchange (ETDEWEB)

Gonzalez, N; Carmenate, C; Pedroso, R; Perez, L O; Alvarez, T R; Gonzalez, N; Felipe, N; Bravo, M [Centro de Investigaciones para el Mejoramiento Animal, Havana (Cuba)

1996-05-01

Goats from 2-5 years old in 15 herds of four breeds, (Saanen, Nubian, Toggenburg and Alpine), were used in three experiments to determine reproductive behaviour (Experiment 1), metabolic profile (Experiment 2) and fertility of induced and synchronized oestrus (Experiment 3). Season, breed and physiological status were significant factors affecting reproductive behaviour and metabolic status (P<0.05). The principal causes of infertility in induced oestrus were failures in conception, early embryonic mortality and anovulatory oestrus. The herds had long intervals from birth to first insemination (306-458 days) and to first pregnancy (471-511 days), and low fertility (14-31%). The breeding patter was similar to breeds in temperate zones. Energy and mineral imbalances were found. Further research is necessary to improve reproductive performance of these breeds under tropical conditions. (author). 25 refs, 3 figs, 4 tabs.

STATUS KESEHATAN GIGI, PERFORMED TREATMENT INDEX DAN REQUIRED TREATMENT INDEX ANAK SEKOLAH DASAR DI KABUPATEN CIANJUR, KARAWANG DAN SERANG

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Magdarina D. Agtini

2012-10-01

Full Text Available Community dental health status for permanent teeth in determined by the DMF-T (Decayed Misssing and Filled Teeth. The DMF-T in a number of industrialized nations shows a tendency to drop while the trend in developing nations is increasing. In Indonesia dental caries is still the foremost problem in oral and dental diseases, Prevalence of dental caries is around 85%-99%. The DMF-T is varied, reflect geographic and ages variations. In three decade's the intensity of dental caries is increasing with each decade, 0,70 DMF-T in 1970 to be 2,30 DMF-T in 1980 and 2,70 DMF-Tin 1990. Goal of dental caries control for 2010 is DMF-T ≤ 1 for 12 years age group. Baseline study is therefore necessary to ascertain DMF-T, PTI (Performed Treatment Index and RTI (Required Treatment Index. The study was implemented in the districts of Cianjur, Karawang and Serang in West Java for two years. The study design was cohort. The respondents  were 1200 pupils aged 8 years, randomly selected with a signifzcantcy grade of p < 0,05 and power of 0,20. The study results showed average of DMF-T at the beginning was 1,52 ± 1,21, and after two years the DMF-T was 2.45 ± 1.51 comprise only of the decayed component, and There was significant different (p=0,000. The DMF-T was low WHO criteria, nevertheless the PTI (1,2% was very low and the RTI (98% was very high. The DMF_T average shows a tendency to increase, with D as the largest component and F (Filling the smallest one. The control of dental caries faces several problems, like the limited number of manpower and facilities, and limited supply of water and electricity incertain areas. Therefore treatment of dental caries with GIC fillings using the ART method should be taken into consideration receive the necessary attention.   Key words:  Status kesehatan gigi, Karies, Performed treatment Index (PTI,  Required Treatment  Index (RTI

Polarity driven morphology of CeO{sub 2}(1 0 0) islands on Cu(1 1 1)

Energy Technology Data Exchange (ETDEWEB)

Stetsovych, O., E-mail: stetsovycholeksandr@gmail.com; Beran, J.; Dvořák, F.; Mašek, K.; Mysliveček, J., E-mail: Josef.Myslivecek@mff.cuni.cz; Matolín, V.

2013-11-15

Thin ceria films supported by metal substrates represent important model systems for reactivity studies in heterogeneous catalysis. Here we report the growth study of the polar CeO{sub 2}(1 0 0) phase as part of a mixed CeO{sub 2}(1 1 1)–CeO{sub 2}(1 0 0) thin film supported by Cu(1 1 1). The two ceria phases grow on different areas of the substrate, what allows a reliable growth characterization of the CeO{sub 2}(1 0 0) islands on Cu(1 1 1). Scanning tunneling microscopy measurements reveal CeO{sub 2}(1 0 0) to grow in the form of highly dispersed three dimensional (3D) islands on a CeO{sub 2}(1 0 0) interfacial layer. The CeO{sub 2}(1 0 0) islands exhibit a 2 × 2 surface reconstruction. The presence of the surface reconstruction together with the highly dispersed growth of CeO{sub 2}(1 0 0) islands corresponds to the requirement for compensation of the surface dipole moment on the CeO{sub 2}(1 0 0). CeO{sub 2}(1 0 0) islands are further characterized by reflection high energy electron diffraction yielding their epitaxial relations with respect to the Cu(1 1 1) substrate. The growth of well characterized CeO{sub 2}(1 0 0) islands supported by Cu(1 1 1) represents a starting point for developing a novel template for structure-related reactivity studies of ceria based model catalysts.

The depolarization performances of 0.97PbZrO3-0.03Ba(Mg1/3Nb2/3)O3 ceramics under hydrostatic pressure

Science.gov (United States)

Su, Rigu; Nie, Hengchang; Liu, Zhen; Peng, Ping; Cao, Fei; Dong, Xianlin; Wang, Genshui

2018-02-01

Several 0.97PbZrO3-0.03Ba(Mg1/3Nb2/3)O3 (0.97PZ-0.03BMN) ceramics were prepared via the columbite precursor method. Their microstructures and pressure-dependent ferroelectric and depolarization performances were then studied. The X-ray diffraction patterns of ground and fresh samples indicate that a main rhombohedral symmetry crystal structure is present in the bulk and that it sits alongside a trace quantity of an orthorhombic antiferroelectric phase that results from the effect of grinding on the surface. The remanent polarization (Pr) of the 0.97PZ-0.03BMN reached 32.4 μC/cm2 at 4.5 kV/mm and ambient pressure. In an in situ pressure-induced current measurement, more than 91% of the retained Pr of the pre-poled sample was released when the pressure was increased from 194 MPa to 238 MPa. That this pressure-driven depolarization should be attributed to the pressure-induced ferroelectric-antiferroelectric phase transition is supported by the emergence of double P-E loops at high hydrostatic pressures. Moreover, the 0.97PZ-0.03BMN ceramics exhibit no temperature-induced phase transitions and little related polarization loss up to 125 °C, which suggests that Pr has excellent thermal stability. The sharp depolarization behavior at low pressures and excellent temperature stability reveal that our 0.97PZ-0.03BMN ceramics exhibit superior performances in mechanical-electrical energy conversion applications.

The association of iron status with educational performance and intelligence among adolescents.

Science.gov (United States)

Dissanayake, D S; Kumarasiri, P V R; Nugegoda, D B; Dissanayake, D M

2009-09-01

The aim was to identify the association of iron status with educational performance and intelligence of adolescents. This was a cross sectional comparative study among adolescents aged 13-15 years. Each iron deficient student was matched with an iron sufficient student from the same school, class and sex. Iron status was based on haemoglobin and serum ferritin levels. The marks for mathematics, science, Sinhala language and social science were considered to assess educational performance. Intelligence was measured by Raven's Standard progressive matrices. All the possible confounders and effect modifiers were considered. Home visits to a sub-sample checked the quality of data. The final analysis included 188 students (94 matched pairs). Neither educational performance nor intelligence showed significant associations with the iron status. The severity of the iron deficiency did not relate to these cognitive variables either. Twenty-three and 8 co-variables showed statistically significant associations with educational performance and intelligence respectively. Following a multiple regression analysis intelligence, the enthusiasm of the student towards learning, occupational ambition, household possession, problems at home and private tuition for mathematics were key factors predicting educational performance. Stunting and educational level of the mother were important factors influencing intelligence. Iron status does not play a major role in educational performance and intelligence of school going adolescents. Several factors affect educational performance and intelligence. This study highlights the difficulty in extrapolating the findings of similar studies to different ecological settings.

Variable number of tandem repeat polymorphisms of the interleukin-1 receptor antagonist gene IL-1RN: a novel association with the athlete status

Directory of Open Access Journals (Sweden)

Ryckman Kelli K

2010-02-01

Full Text Available Abstract Background The interleukin-1 (IL-1 family of cytokines is involved in the inflammatory and repair reactions of skeletal muscle during and after exercise. Specifically, plasma levels of the IL-1 receptor antagonist (IL-1ra increase dramatically after intense exercise, and accumulating evidence points to an effect of genetic polymorphisms on athletic phenotypes. Therefore, the IL-1 family cytokine genes are plausible candidate genes for athleticism. We explored whether IL-1 polymorphisms are associated with athlete status in European subjects. Methods Genomic DNA was obtained from 205 (53 professional and 152 competitive non-professional Italian athletes and 458 non-athlete controls. Two diallelic polymorphisms in the IL-1β gene (IL-1B at -511 and +3954 positions, and a variable number tandem repeats (VNTR in intron 2 of the IL-1ra gene (IL-1RN were assessed. Results We found a 2-fold higher frequency of the IL-1RN 1/2 genotype in athletes compared to non-athlete controls (OR = 1.93, 95% CI = 1.37-2.74, 41.0% vs. 26.4%, and a lower frequency of the 1/1 genotype (OR = 0.55, 95% CI = 0.40-0.77, 43.9% vs. 58.5%. Frequency of the IL-1RN 2/2 genotype did not differ between groups. No significant differences between athletes and controls were found for either -511 or +3954 IL-1B polymorphisms. However, the haplotype (-511C-(+3954T-(VNTR2 was 3-fold more frequent in athletes than in non-athletes (OR = 3.02, 95% CI = 1.16-7.87. Interestingly, the IL-1RN 1/2 genotype was more frequent in professional than in non-professional athletes (OR = 1.92, 95% CI = 1.02-3.61, 52.8% vs. 36.8%. Conclusions Our study found that variants at the IL-1ra gene associate with athletic status. This confirms the crucial role that cytokine IL-1ra plays in human physical exercise. The VNTR IL-1RN polymorphism may have implications for muscle health, performance, and/or recovery capacities. Further studies are needed to assess these specific issues. As VNTR IL-1RN

Time of Day and Training Status Both Impact the Efficacy of Caffeine for Short Duration Cycling Performance.

Science.gov (United States)

Boyett, James C; Giersch, Gabrielle E W; Womack, Christopher J; Saunders, Michael J; Hughey, Christine A; Daley, Hannah M; Luden, Nicholas D

2016-10-14

This project was designed to assess the effects of time of day and training status on the benefits of caffeine supplementation for cycling performance. Twenty male subjects (Age, 25 years; Peak oxygen consumption, 57 mL·kg -1 ·min -1 ) were divided into tertiles based on training levels, with top and bottom tertiles designated as 'trained' ( n = 7) and 'untrained' ( n = 7). Subjects completed two familiarization trials and four experimental trials consisting of a computer-simulated 3-km cycling time trial (TT). The trials were performed in randomized order for each combination of time of day (morning and evening) and treatment (6mg/kg of caffeine or placebo). Magnitude-based inferences were used to evaluate all treatment effects. For all subjects, caffeine enhanced TT performance in the morning (2.3% ± 1.7%, 'very likely') and evening (1.4% ± 1.1%, 'likely'). Both untrained and trained subjects improved performance with caffeine supplementation in the morning (5.5% ± 4.3%, 'likely'; 1.0% ± 1.7%, 'likely', respectively), but only untrained subjects rode faster in the evening (2.9% ± 2.6%, 'likely'). Altogether, our observations indicate that trained athletes are more likely to derive ergogenic effects from caffeine in the morning than the evening. Further, untrained individuals appear to receive larger gains from caffeine in the evening than their trained counterparts.

Block Storage Service: Status and Performance

CERN Document Server

Van der Ster, Daniel

2014-01-01

This memo summarizes the current status of the Ceph block storage service as it is used for OpenStack Cinder Volumes and Glance Images as of May 2014. We present the block storage activity on the current cluster, measuring IOPS and latencies, and present a cost/benefit analysis of using SSDs to optimize the cost and performance efficiency of the service. During tests in collaboration with IT-CF, we have concluded that by adding SSDs as the synchronous write journals (used to guarantee data durability), we are able increase the IOPS capacity by 4-5 times, at a cost of decreasing the available volume by 20%. Further, the testing has shown that the Ceph implementation is able to operate at the limit of the hardware performance; software-induced performance limitations were not yet observed in either the spinning disk or SSD configurations. In addition, we believe that increasing small write performance with SSDs is applicable only to the block storage use-case; high-bandwidth use-cases such as physics data stora...

Iron, zinc, copper and magnesium nutritional status in Mexican children aged 1 to 11 years.

Science.gov (United States)

Morales-Ruán, Ma del Carmen; Villalpando, Salvador; García-Guerra, Armando; Shamah-Levy, Teresa; Robledo-Pérez, Ricardo; Avila-Arcos, Marco Antonio; Rivera, Juan A

2012-01-01

To describe the micronutrient nutritional status of a national sample of 1-11 year old Mexican children surveyed in 2006 in National Health and Nutrition Survey (ENSANUT 2006) and their association with dietary and sociodemographic factors. Serum samples were used (n=5 060) to measure the concentrations of ferritin, transferrin receptor, zinc, copper and magnesium. Prevalence of deficiencies in 1-4 and 5-11y old children were for iron (using low ferritin) 26.0 and 13.0%; zinc, 28.1 and 25.8%, respectively; and copper, ≈30% in both age groups. Magnesium low serum concentrations (MLSC), were found in 12.0% and 28.4% of the children, respectively. Being beneficiary of Liconsa (OR=0.32; C.I.95%, 0.17-0.61) or belonging to higher socioeconomic status (OR=0.63; C.I.95%, 0.41-0.97) were protective against iron deficiency. Increasing age (OR=0.59; C.I.95%, 1.19-1.32) and living in the Central Region (OR=0.59; C.I.95%, 0.36-0.97) were protective against MLSC. Deficiencies of iron and zinc are serious public health problems in Mexican children.

Smoking status and cognitive performance among vocational school students in Beijing, China.

Science.gov (United States)

Hu, Pengjuan; Huang, Lili; Zhou, Shuang; Shi, Qiang; Xiao, Dan; Wang, Chen

2018-02-01

In countries where smoking is associated with lower socioeconomic status, smokers tend to perform worse on cognitive tasks than non-smokers. China is now undergoing a similar process with a recent study showing that there is a reduced cognitive performance in middle aged but not in elderly smokers. We examined the links between smoking status and cognitive functioning among vocational school students in Beijing, China. A total of 213 students aged 16-20 (98 smokers and 115 non-smokers) were recruited from three vocational schools in Beijing. Participants completed three subtests of Wechsler Adult Intelligence Scale (WAIS) (information, arithmetic, digit span) and Dysexecutive Questionnaire (DEX). Smokers also completed a cigarette smoking questionnaire and Fagerstrom Test of Nicotine Dependence (FTND). Smokers performed worse than non-smokers in tests of arithmetic and digit span forward (t = 4.25, 2.05, both P < .05). Scores on digit span backward did not differentiate smokers and non-smokers, but among smokers, the performance on this subtest was related to the age of starting smoking (r = 0.26, p < .001). Cognitive performance in smokers was not related to tobacco dependence or intensity of smoking. Compared to non-smokers, smokers had a higher total DEX score and higher scores on three of its five subscales (Inhibition, Knowing-doing dissociation and Social regulation, all p < .05). Another subscale, In-resistance, did not differentiate smokers and non-smokers, but differentiated smokers with lower and higher levels of nicotine dependence (t = -2.12, p < .05). Smokers performed worse on some cognitive tasks than non-smokers and scored higher on a questionnaire assessing executive dysfunction. Copyright © 2017. Published by Elsevier Ltd.

Periodontal status during pregnancy and postpartum.

Directory of Open Access Journals (Sweden)

Maximino González-Jaranay

Full Text Available Different studies have documented an association between periodontal disease and low birth-weight delivery. Hence, knowledge of periodontal status during pregnancy and postpartum is important in order to reduce the risks of both diseases. This study aimed to analyze periodontal status at successive stages of pregnancy and 3-6 weeks postpartum in women with initial periodontal alterations.Ninety-six pregnant women were examined at 8-10 weeks (pregnancy diagnosis, baseline, 21-23 weeks and 34-36 weeks of gestation and at 40 days postpartum to record plaque scores, clinically assessed gingival inflammation and probing depth (mean depth and % sites with depth >3 mm. Bivariate and multivariate analyses were performed. Type 1 (α error was established at 0.05.Plaque Index increased (p = 0.043 throughout pregnancy (baseline, 42%±0.18; 21-23 weeks, 42.6%±0.14; 34-36 weeks, 45.6%±0.13 and decreased postpartum (44.8%±0-13. Gingival Index increased (p3 mm increased (p<0.001 throughout pregnancy (baseline, 17.6%±0.16; 21-23 weeks, 23.9%±0.17; 34-36 weeks, 31.1%±0.17 and decreased postpartum (21.2%±0.17 but remained significantly (p<0.02 higher than at baseline.Periodontal status deteriorates during gestation but improves postpartum.

Concordance of Barthel Index, ECOG-PS, and Palliative Performance Scale in the assessment of functional status in patients with advanced medical diseases.

Science.gov (United States)

Hernández-Quiles, C; Bernabeu-Wittel, M; Pérez-Belmonte, L M; Macías-Mir, P; Camacho-González, D; Massa, B; Maiz-Jiménez, M; Ollero-Baturone, M

2017-09-01

Analysing most relevant clinical features and concordance between different functional scales in patients with advanced medical diseases (PAMD). Cross-sectional multicentre study that included PAMD (heart, lung, kidney, liver, and neurological diseases) in hospital settings from February 2009 to October 2010. We analysed clinical, biological and functional features in performing activities of daily living (ADL) by medians of Barthel Index (BI); additionally we assessed their performance status by medians of Eastern Cooperative Oncology Group-Performance Status (ECOG-PS) and Palliative Performance Scale (PPS) scores. We evaluated the concordance of these instruments in assessing functional impairment by κ and intraclass correlation coefficient tests. 1847 patients were included (average age 79 years, 50.1% men). Most common symptoms were dyspnoea (62.31%), asthenia (23%) and delirium (20.14%). Functional assessment showed a high prevalence of severe or total impairment in performing basic ADL by medians of used instruments (BI median=35 (IQR=70), and 52.1% of patients with severe-total impairment; ECOG-PS median=2 (IQR 30), and 44% of patients with severe-total impairment; and PPS median=50 (IQR 30), and 32% of patients with severe-total impairment). Concordance among these instruments was acceptably good ( κ indexes ranging from 0.653 to 0.745 (pmanagement. Assessment of functional ability in this population by BI, ECOG-PS, and PPS showed good concordance. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

Investigation on the electrochemical activation process of Li1.20Ni0.32Co0.004Mn0.476O2

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Daichun Tang

2014-08-01

Full Text Available The lithium-rich layered oxides are one of the most attractive cathode materials for lithium-ion batteries. Here, two types of Li1.20Ni0.32Co0.004Mn0.476O2 were synthesized using Li2CO3 and LiOH as lithium sources. An electrochemical activation process occurs in Li1.2Ni0.32Co0.004Mn0.476O2 prepared from Li2CO3 (LLO-1, while no obvious activation in Li1.2Ni0.32Co0.004Mn0.476O2 prepared from LiOH (LLO-2 is observed. Via advanced scanning transmission electron microscopy (STEM, we found that Li2MnO3-like structure is rich in the surface region of LLO-2. The study provides a direct explanation for the electrochemical activation of lithium-rich materials. The sample with more LiMO2-like phase at the surface region shows a better cycling performance. It is likely that more LiMO2-like phase at the surface region could stabilize the interface and improve the cycling performance of the Li-rich cathode materials.

Creep behavior of perovskite-type oxides Ba0.5Sr0.5(Co0.8Fe0.2)1−xZrxO3−δ

NARCIS (Netherlands)

Stournari, V.; ten Donkelaar, S.F.P.; Malzbender, J.; Beck, T.; Singheiser, L.; Bouwmeester, Henricus J.M.

2015-01-01

Compressive creep tests have been performed on perovskite-type oxides Ba0.5Sr0.5(Co0.8Fe0.2)1–xZrxO3−δ (BSCF-Z100·x), where x = 0.01, 0.03, 0.05 and 0.1, for the use as oxygen transport membrane, in air at 800–950 °C and at nominal stresses of 30 MPa and 63 MPa. X-ray diffraction and microstructural

The antioxidant status of coenzyme Q10 and vitamin E in children with type 1 diabetes.

Science.gov (United States)

Alkholy, Usama M; Abdalmonem, Nermin; Zaki, Ahmed; Elkoumi, Mohamed A; Hashim, Mustafa I Abu; Basset, Maha A A; Salah, Hossam E

2018-02-07

The purpose of this study was to evaluate the antioxidant status of plasma vitamin E and plasma and intracellular coenzyme Q10 in children with type 1 diabetes. This case-control study was conducted on 72 children with type 1 diabetes and compared to 48 healthy children, who were age, sex, and ethnicity-matched. The diabetic children were divided according to their glycosylated hemoglobin (A1c %) into two groups: poor and good glycemic control groups. All children underwent full history taking, clinical examination, and laboratory measurement of complete blood count, A1c %, plasma cholesterol, triglycerides, and vitamin E levels and coenzyme Q10 levels in plasma, erythrocytes, and platelets. Children with poor glycemic control showed significantly higher plasma vitamin E, coenzyme Q10, triglycerides, low-density lipoproteins, waist circumference/height ratio, cholesterol levels, and lower high-density lipoproteins and platelet coenzyme Q10 redox status in comparison to those with good glycemic control and the control group (p<0.05). Plasma coenzyme Q10 showed a positive correlation with the duration of type 1 diabetes, triglycerides, cholesterol, vitamin E, and A1c %, and negative correlation with the age of the diabetic group (p<0.05). The platelet redox status showed a negative correlation with the A1c % levels (r=-0.31; p=0.022) and the duration of type 1 diabetes (r=-0.35, p=0.012). Patients with type 1 diabetes, especially poorly controlled, had elevation of plasma vitamin E and coenzyme Q10 levels and decreased platelet redox status of coenzyme Q10, which may be an indicator of increased oxidative stress. Copyright © 2018 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.

ATLAS detector performance in Run1: Calorimeters

CERN Document Server

Burghgrave, B; The ATLAS collaboration

2014-01-01

ATLAS operated with an excellent efficiency during the Run 1 data taking period, recording respectively in 2011 and 2012 an integrated luminosity of 5.3 fb-1 at √s = 7 TeV and 21.6 fb-1 at √s = 8TeV. The Liquid Argon and Tile Calorimeter contributed to this effort by operating with a good data quality efficiency, improving over the whole Run 1. This poster presents the Run 1 overall status and performance, LS1 works and Preparations for Run 2.

The role of Triton surfactant in anisotropic etching of {1 1 0} reflective planes on (1 0 0) silicon

Science.gov (United States)

Resnik, Drago; Vrtacnik, Danilo; Aljancic, Uros; Mozek, Matej; Amon, Slavko

2005-06-01

Etching characteristics and properties of {1 1 0} silicon crystal planes used as 45° optical mirrors for deflecting optical beams from/to optical fibers were investigated. Fiber aligning grooves and passive mirror-like planes were realized by wet micromachining of (1 0 0) silicon in KOH IPA and TMAH IPA systems. Implementation of Triton-x-100 surfactant as an additive to 25% TMAH in anisotropic etching of {1 1 0} silicon passive mirror planes is reported and discussed. It was found that Triton-x-100 contents in the range of 10 200 ppm to the 25% TMAH water etchant significantly increase the anisotropy mostly by decreasing the {1 1 0} etch rate and retaining the {1 0 0} etch rate. It is also shown that {1 1 0} surface roughness is substantially improved compared to two other etching systems. Furthermore, efficient convex corner underetching reduction is demonstrated. The results of optical characterization of passive mirrors with 632 nm incident light show reduced scattering of reflected optical beam due to improved microroughness for mirrors made by TMAH Triton. For the reflection of the optical beam with 1.33 µm and 1.54 µm wavelengths, sputtered layer of gold is used as reflective coating on silicon mirrors thus increasing the reflected optical beam intensity by an additional 8%.

Perbandingan antara Kombinasi Bupivakain 0,125% dan Dexmedetomidin 1 µg/Kgbb dengan Bupivakain 0,125% Melalui Blok Kaudal Terhadap Lama Analgesi Pascaoperasi Hipospadia

Directory of Open Access Journals (Sweden)

Sardinata

2013-04-01

Full Text Available Caudal blockage is the most frequently used regional anestesia technique in pediatric surgery. Various local anesthetic agents have been frequently used in this technique. Bupivacaine is one of the most used local anesthetics due to its long duration of action. Dexmedetomidin is an α2agonist that is used as adjuvant in lengthening bupivacaine duration when it is administered via caudal blockage. In increasing its effectiveness, the combination of bupivacaine with dexmedetomidin in low concentrationd and low dose can be given. This study was performed to assess the postoperative analgesia duration using caudal blockage between the combined 0.125% bupivacaine-1µg/Kg BW dexmedetomidin and 0.125% bupivacaine solely in pediatric patients having hypospadic surgery. The study was applied to 30 pediatric patients with ASA I and II physical status, and aged 1-6 years that received hypospadic surgery with general anesthesia, to whom caudal blockage applied postoperatively. The patients were divided into two groups. One group (BD group was treated using the combined 0.125% bupivacaine-1 µg/Kg BW dexmedetomidin (0.5 cc/kg BW, the other group (B group was treated with 0.125% bupivacaine (0.5 cc/kb BW as control group. Postoperative analgesia duration was recorded. The data of the study results were assessed using Mann-Whitney test. Postoperative analgesia duration of BD group (863.0 [36.34] minutes was very significantly (p<0.001 longer than that in B group (378.08 [37.87] minutes. The conclusion of this study indicated that the use of combined 0.125% bupivacaine-1 µg/Kg BW dexmedetomidin for caudal blockage as analgetic agent after hypospadic surgery resulted longer analgesia duration than that of 0.125% bupivacaine solely

Impedance spectroscopy studies on lead free Ba1-xMgx(Ti0.9Zr0.1)O3 ceramics

Science.gov (United States)

Ben Moumen, S.; Neqali, A.; Asbani, B.; Mezzane, D.; Amjoud, M.; Choukri, E.; Gagou, Y.; El Marssi, M.; Luk'yanchuk, Igor A.

2018-06-01

Ba1-xMgx(Ti0.9Zr0.1)O3 (x = 0.01 and 0.02) ceramics were prepared using the conventional solid state reaction. Rietveld refinement performed on X-ray diffraction patterns indicates that the samples are tetragonal crystal structure with P4mm space group. By increasing Mg content from 1 to 2% the unit cell volume decreased. Likewise, the grains size is greatly reduced from 10 μm to 4 μm. The temperature dependence of dielectric constants at different frequencies exhibited typical relaxor ferroelectric characteristic, with sensitive dependence in frequency and temperature for ac conductivity. The obtained activation energy values were correlated to the proposed conduction mechanisms.

LLCEDATA and LLCECALC for Windows version 1.0, Volume 1: User's manual

International Nuclear Information System (INIS)

McFadden, J.G.

1998-01-01

LLCEDATA and LLCECALC for Windows are user-friendly computer software programs that work together to determine the proper waste designation, handling, and disposition requirements for Long Length Contaminated Equipment (LLCE). LLCEDATA reads from a variety of data bases to produce an equipment data file (EDF) that represents a snapshot of both the LLCE and the tank it originates from. LLCECALC reads the EDF and a gamma assay (AV2) file that is produced by the Flexible Receiver Gamma Energy Analysis System. LLCECALC performs corrections to the AV2 file as it is being read and characterizes the LLCE. Both programs produce a variety of reports, including a characterization report and a status report. The status report documents each action taken by the user, LLCEDATA, and LLCECALC. Documentation for LLCEDATA and LLCECALC for Windows is available in three volumes. Volume 1 is a user's manual, which is intended as a quick reference for both LLCEDATA and LLCECALC. Volume 2 is a technical manual, and Volume 3 is a software verification and validation document

Accuracy of sentinel lymph node biopsy for the assessment of auxiliary status in patients with early (T1) breast carcinoma

International Nuclear Information System (INIS)

Gurleyik, G.; Sekmen, U.; Saglam, A.; Aker, F.

2005-01-01

Objective: To determine the accuracy of SLN biopsy for the assessment of auxiliary status, and prognostic markers leading to lymphatic metastasis in patients with early (T1) breast cancer. Design: Cross-sectional study. Place and Duration of Study: Department of Surgery, Teaching and Research Hospital. Between January 2000 and August 2004. Patients and Methods: SLN mapping by blue dye method was performed on 39 patients with T1 breast carcinoma. SLNs, level 1 and 2 auxiliary nodes were dissected and excised. The size, pathologic features of the primary tumor, SLNs and other auxiliary nodes, and hormone receptors were evaluated by histopathologic examination. The rate of SLNs and non SLNs involvement, and demographic, clinical and pathologic risk factors leading to nodal metastasis were established. The diagnostic accuracy of SLN for auxiliary status was calculated. Results: SLNs were identified in 37 (95%) patients. The axilla had metastasis in 11 (28%) patients. Malignant cells involved SLNs in 8 patients. Non-SLNs had metastasis in 3 patients without SLN involvement. The sensitivity, specificity and accuracy of SLN biopsy for predicting auxiliary status was calculated as 73%, 100% and 92% respectively. Four of 5 patients T1c tumors (p=0.14) and lymphovascular invasion (p=0.0004). Conclusion: SLN biopsy with high diagnostic accuracy may prevent unnecessary disection of the axilla in the majority of patients with early (T1) breast carcinoma. Some risk factors as pre-menopausal status, absence of hormone receptors, and presence of lymphovascular invasion must be taken into account as important determinant of non-SLNs metastasis. (author)

High performance Sm{sub 0.5}Sr{sub 0.5}CoO{sub 3}-La{sub 0.8}Sr{sub 0.2}Ga{sub 0.8}Mg{sub 0.15}Co{sub 0.05}O{sub 3} composite cathodes

Energy Technology Data Exchange (ETDEWEB)

Wang, Shizhong; Zou, Yuman [College of Chemistry and Chemical Engineering, Department of Chemistry, Xiamen University, Xiamen 361005, Fujian (China)

2006-06-15

High performance Sm{sub 0.5}Sr{sub 0.5}CoO{sub 3}(SSC)-La{sub 0.8}Sr{sub 0.2}Ga{sub 0.8}Mg{sub 0.15}Co{sub 0.05}O{sub 3} (LSGMC5) composite cathodes for intermediate temperature solid oxide fuel cells (ITSOFC) were prepared and characterized. The SSC powders were synthesized using the glycine-nitrate method and La{sub 0.8}Sr{sub 0.2}Ga{sub 0.8}Mg{sub 0.15}Co{sub 0.05}O{sub 3}(LSGMC5) powders were synthesized using the citrate method. The calcining temperature for the SSC and LSGMC5 powders had strong effect on the microstructure of the composite electrode and electrode/electrolyte interface, which affected the performance of the SSC-LSGMC5 electrode strongly. The electrode based on SSC calcined at 1223K and LSGMC5 calcined at 1273K exhibited the highest performance among the electrodes studied. The electrode resistance was about 0.07{omega}cm{sup 2}, and the overpotential under 1Acm{sup -2} current density was as low as 0.077V at 973K in oxygen, which could be an ideal cathode for ITSOFC based on lanthanum gallate electrolytes. (author)

Effects of preventive versus "on-demand" nutritional support on paid labour productivity, physical exercise and performance status during PEG-interferon-containing treatment for hepatitis C.

Science.gov (United States)

Huisman, Ellen J; van Meer, Suzanne; van Hoek, Bart; van Soest, Hanneke; van Nieuwkerk, Karin M J; Arends, Joop E; Siersema, Peter D; van Erpecum, Karel J

2016-04-01

Deterioration of nutritional status during PEG-interferon containing therapy for chronic hepatitis C can be ameliorated by preventive nutritional support. We aimed to explore whether such support also affects paid labour productivity, physical exercise and performance status. In this prospective randomized controlled trial (J Hepatol 2012;57:1069-75), 53 patients with chronic hepatitis C had been allocated to "on demand" support (n=26: nutritional intervention if weight loss>5%) or preventive support (n=27: regular dietary advice plus energy- and protein-rich evening snack) during PEG-interferon-containing therapy. Paid labour productivity, physical exercise and performance status were evaluated at baseline, after 24 and (if applicable) after 48 weeks of treatment. At baseline, 46% of patients performed paid labour and 62% performed some kind of physical exercise. Furthermore, most patients were able to carry out normal activity with only minor symptoms of disease (mean Karnofsky performance score: 94). Decreases of paid labour productivity (-21% vs. -70%, P=0.003), physical exercise activity (-43% vs. -87%, P=0.005) and Karnofsky performance scores (-12% vs. -24%, Plabour productivity, physical exercise and performance status during PEG-interferon-containing treatment for chronic hepatitis C. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

Elevated electrochemical performance of (NH4)3AlF6-coated 0.5Li2MnO3·0.5LiNi1/3Co1/3Mn1/3O2 cathode material via a novel wet coating method

International Nuclear Information System (INIS)

Xu, Guofeng; Li, Jianling; Xue, Qingrui; Dai, Yu; Zhou, Hongwei; Wang, Xindong; Kang, Feiyu

2014-01-01

A novel wet method of (NH 4 ) 3 AlF 6 coating was explored to enhance the electrochemical performance of Mn-based solid-solution cathode material 0.5Li 2 MnO 3 ·0.5LiNi 1/3 Co 1/3 Mn 1/3 O 2 . The X-ray powder diffraction patterns show that the coating material is pure-phase (NH 4 ) 3 AlF 6 and both pristine and coated samples can be indexed to hexagonal α-NaFeO 2 layered structure with space group of R-3 m. The field-emission scanning electron microscope images and the energy dispersive X-ray spectroscopy show that (NH 4 ) 3 AlF 6 is successfully coated on the surface of active particle. The (NH 4 ) 3 AlF 6 coated electrodes exhibit improved electrochemical performance, for instance, the initial charge-discharge efficiency was promoted by 5% (NH 4 ) 3 AlF 6 coating, the 1 wt.% and 3 wt.% coated electrodes deliver elevated cycling ability which is ascribed to the lower resistance between electrode and electrolyte as indicated by AC impedance measurement at different cycles. In addition, the coated-electrodes also give enhanced rate capability particularly for 1 wt.% NAF-coated electrode performing surprising capacity of 143.4 mAh g −1 at 5 C higher than that of 109.4 mAh g −1 for pristine electrode. Furthermore, the 1 wt.% NAF-coated electrode also shows improved cycle and rate performance at 55°C

Academic performance of Korean children is associated with dietary behaviours and physical status.

Science.gov (United States)

Kim, Hye-Young P; Frongillo, Edward A; Han, Sung-Sook; Oh, Se-Young; Kim, Woo-Kyung; Jang, Young-Ai; Won, Hye-Sook; Lee, Hyun-Sook; Kim, Sook-He

2003-01-01

The purpose of this study was to obtain a fuller understanding of the association of dietary behaviours, physical status and socio-economic status with academic performance in Korean teenagers. The subjects in this study were 6,463 boys and girls, in grade 5, 8, and 11 in Korea. A self-administered questionnaire and the food-frequency form were used. Grade point average (GPA), height, weight, and physical fitness score for the year were recorded from the school record. The academic performance of students was strongly associated with dietary behaviours, especially with regularity of three meals even after control for parent's education level. Regular breakfast and lunch were more important in grades 5 and 8, while regular dinner was more related with academic performance in grade 11. Small, positive associations of height and physical fitness to academic performance were also found. The relative importance of regularity of meals was greater than that of socio-economic status and physical status in older teenagers. The results of this study suggest that accommodation of better dietary environment and nutrition education for three regular meals is recommended.

Indico 1.0

International Nuclear Information System (INIS)

Lopez, J B Gonzalez; Avilés, A; Baron, T; Ferreira, P; Kolobara, B; Pugh, M A; Resco, A; Trzaskoma, J P

2014-01-01

Indico has evolved into the main event organization software, room booking tool and collaboration hub for CERN. The growth in its usage has only accelerated during the past 9 years, and today Indico holds more that 215,000 events and 1,100,000 files. The growth was also substantial in terms of functionalities and improvements. In the last year alone, Indico has matured considerably in 3 key areas: enhanced usability, optimized performance and additional features, especially those related to meeting collaboration. Along the course of 2012, much activity has centred around consolidating all this effort and investment into 'version 1.0', recently released in 2013.Version 1.0 brings along new features, such as the Microsoft Exchange calendar synchronization for participants, many new and clean interfaces (badges and poster generation, list of contributions, abstracts, etc) and so forth. But most importantly, it brings a message: Indico is now stable, consolidated and mature after more than 10 years of non-stop development. This message is addressed not only to CERN users but also to the many organisations, in or outside HEP, which have already installed the software, and to others who might soon join this community. In this document, we describe the current state of the art of Indico, and how it was built. This does not mean that the Indico software is complete, far from it! We have plenty of new ideas and projects that we are working on and which we have shared during CHEP 2013.

Diagnosis of temporomandibular dysfunction syndrome - image quality at 1.5 and 3.0 Tesla magnetic resonance imaging

Energy Technology Data Exchange (ETDEWEB)

Schmid-Schwap, Martina; Bristela, Margit; Piehslinger, Eva [Bernhard Gottlieb University Clinic of Dentistry, Department of Fixed and Removable Prosthodontics, Vienna (Austria); Drahanowsky, Wolfgang; Robinson, Soraya [Diagnostic Center Urania, Vienna (Austria); Kundi, Michael [Medical University of Vienna, Institute of Environmental Health, Center for Public Health, Vienna (Austria)

2009-05-15

The purpose of this study was to examine the differences in expert ratings of quality of magnetic resonance images (MRI) of the temporomandibular joint in 24 patients with suspected anterior disc displacement examined in randomized order at 1.5 and 3.0 T. Parasagittal (closed and opened mouth) and paracoronal sections were performed with a surface coil. Two experienced examiners blinded to patient status and type of MRI diagnosed the images according to position of condyle, position and changes in the signal, and disc shape. In addition, perceptibility of position and disc shape were assessed. A highly significant difference in the perceptibility of disc shape (P < 0.001) and position (P < 0.001) was obtained. With comparable examination sequences and identical resolution, the 3.0 T MRI of the temporomandibular joint increases the perceptibility of joint structures. (orig.)

8 CFR 1209.1 - Adjustment of status of refugees.

Science.gov (United States)

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Adjustment of status of refugees. 1209.1... IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS OF REFUGEES AND ALIENS GRANTED ASYLUM § 1209.1 Adjustment of status of refugees. The provisions of this section shall provide the sole and exclusive procedure for...

A longitudinal study of childhood obesity, weight status change, and subsequent academic performance in Taiwanese children.

Science.gov (United States)

Chen, Li-Jung; Fox, Kenneth R; Ku, Po-Wen; Wang, Ching-Hui

2012-09-01

This study examined the association among childhood obesity, weight status change, and subsequent academic performance at 6-year follow-up. First-grade students from one elementary school district in Taichung City, Taiwan were followed for 6 years (N = 409). Academic performance was extracted from the school records at the end of each grade. Weight and height were measured at the beginning of each grade. A weight change variable was created based on each child's weight status difference at grades 1 and 6. A multivariate linear regression model for predicting academic performance at grade 6 was developed with adjustment for individual characteristics and family factors. A latent growth curve (LGC) showed the association between changes in body mass index (BMI) and in academic performance across a 6-year period. BMI in children increased significantly across 6 years. The rate of increase in BMI over 6 years was higher for children with higher baseline BMIs than it was for children with lower baseline BMIs. However, BMI changes were not significantly associated with changes of academic performance. There was no significant relationship between initial obesity or change in weight status and subsequent academic performance. It appears that either being or becoming overweight/obese did not impact academic achievement for these Taiwanese children. © 2012, American School Health Association.

Study of Ni/Si(1 0 0) solid-state reaction with Al addition

International Nuclear Information System (INIS)

Huang Yifei; Jiang Yulong; Ru Guoping; Li Bingzong

2008-01-01

The characteristics of Ni/Si(1 0 0) solid-state reaction with Al addition (Ni/Al/Si(1 0 0), Ni/Al/Ni/Si(1 0 0) and Al/Ni/Si(1 0 0)) is studied. Ni and Al films were deposited on Si(1 0 0) substrate by ion beam sputtering. The solid-state reaction between metal films and Si was performed by rapid thermal annealing. The sheet resistance of the formed silicide film was measured by four-point probe method. The X-ray diffraction (XRD) was employed to detect the phases in the silicide film. The Auger electron spectroscopy was applied to reveal the element profiles in depth. The influence of Al addition on the Schottky barrier heights of the formed silicide/Si diodes was investigated by current-voltage measurements. The experimental results show that NiSi forms even with the addition of Al, although the formation temperature correspondingly changes. It is revealed that Ni silicidation is accompanied with Al diffusion in Ni film toward the film top surface and Al is the dominant diffusion species in Ni/Al system. However, no Ni x Al y phase is detected in the films and no significant Schottky barrier height modulation by the addition of Al is observed

Status of uncertainty assessment in k0-NAA measurement. Anything still missing?

International Nuclear Information System (INIS)

Borut Smodis; Tinkara Bucar

2014-01-01

Several approaches to quantifying measurement uncertainty in k 0 -based neutron activation analysis (k 0 -NAA) are reviewed, comprising the original approach, the spreadsheet approach, the dedicated computer program involving analytical calculations and the two k 0 -NAA programs available on the market. Two imperfectness in the dedicated programs are identified, their impact assessed and possible improvements presented for a concrete experimental situation. The status of uncertainty assessment in k 0 -NAA is discussed and steps for improvement are recommended. It is concluded that the present magnitude of measurement uncertainty should further be improved by making additional efforts in reducing uncertainties of the relevant nuclear constants used. (author)

Infant and child feeding index and nutritional status of 0-24 month ...

African Journals Online (AJOL)

Method: A cross sectional study was carried out to assess infant feeding practices of mothers and its effect on child nutritional status. A multistage random sampling procedure was used to select 450 mothers of children between the ages of 0-24 months. Breastfeeding and complementary feeding practices were examined ...

Clinical Neuropathology practice news 1-2014: Pyrosequencing meets clinical and analytical performance criteria for routine testing of MGMT promoter methylation status in glioblastoma

Science.gov (United States)

Preusser, Matthias; Berghoff, Anna S.; Manzl, Claudia; Filipits, Martin; Weinhäusel, Andreas; Pulverer, Walter; Dieckmann, Karin; Widhalm, Georg; Wöhrer, Adelheid; Knosp, Engelbert; Marosi, Christine; Hainfellner, Johannes A.

2014-01-01

Testing of the MGMT promoter methylation status in glioblastoma is relevant for clinical decision making and research applications. Two recent and independent phase III therapy trials confirmed a prognostic and predictive value of the MGMT promoter methylation status in elderly glioblastoma patients. Several methods for MGMT promoter methylation testing have been proposed, but seem to be of limited test reliability. Therefore, and also due to feasibility reasons, translation of MGMT methylation testing into routine use has been protracted so far. Pyrosequencing after prior DNA bisulfite modification has emerged as a reliable, accurate, fast and easy-to-use method for MGMT promoter methylation testing in tumor tissues (including formalin-fixed and paraffin-embedded samples). We performed an intra- and inter-laboratory ring trial which demonstrates a high analytical performance of this technique. Thus, pyrosequencing-based assessment of MGMT promoter methylation status in glioblastoma meets the criteria of high analytical test performance and can be recommended for clinical application, provided that strict quality control is performed. Our article summarizes clinical indications, practical instructions and open issues for MGMT promoter methylation testing in glioblastoma using pyrosequencing. PMID:24359605

Routine clinical knee MR reports: comparison of diagnostic performance at 1.5 T and 3.0 T for assessment of the articular cartilage

Energy Technology Data Exchange (ETDEWEB)

Mandell, Jacob C.; Rhodes, Jeffrey A.; Shah, Nehal; Gaviola, Glenn C.; Smith, Stacy E. [Brigham and Women' s Hospital, Division of Musculoskeletal Imaging and Intervention, Department of Radiology, Boston, MA (United States); Gomoll, Andreas H. [Brigham and Women' s Hospital, Cartilage Repair Center, Department of Orthopedic Surgery, Boston, MA (United States)

2017-11-15

Accurate assessment of knee articular cartilage is clinically important. Although 3.0 Tesla (T) MRI is reported to offer improved diagnostic performance, literature regarding the clinical impact of MRI field strength is lacking. The purpose of this study is to compare the diagnostic performance of clinical MRI reports for assessment of cartilage at 1.5 and 3.0 T in comparison to arthroscopy. This IRB-approved retrospective study consisted of 300 consecutive knees in 297 patients who had routine clinical MRI and arthroscopy. Descriptions of cartilage from MRI reports of 165 knees at 1.5 T and 135 at 3.0 T were compared with arthroscopy. The sensitivity, specificity, percent of articular surfaces graded concordantly, and percent of articular surfaces graded within one grade of the arthroscopic grading were calculated for each articular surface at 1.5 and 3.0 T. Agreement between MRI and arthroscopy was calculated with the weighted-kappa statistic. Significance testing was performed utilizing the z-test after bootstrapping to obtain the standard error. The sensitivity, specificity, percent of articular surfaces graded concordantly, and percent of articular surfaces graded within one grade were 61.4%, 82.7%, 62.2%, and 77.5% at 1.5 T and 61.8%, 80.6%, 59.5%, and 75.6% at 3.0 T, respectively. The weighted kappa statistic was 0.56 at 1.5 T and 0.55 at 3.0 T. There was no statistically significant difference in any of these parameters between 1.5 and 3.0 T. Factors potentially contributing to the lack of diagnostic advantage of 3.0 T MRI are discussed. (orig.)

The significance of tumoral ERCC1 status in patients with locally advanced cervical cancer treated with chemoradiation therapy: a multicenter clinicopathologic analysis.

Science.gov (United States)

Doll, Corinne M; Aquino-Parsons, Christina; Pintilie, Melania; Klimowicz, Alexander C; Petrillo, Stephanie K; Milosevic, Michael; Craighead, Peter S; Clarke, Blaise; Lees-Miller, Susan P; Fyles, Anthony W; Magliocco, Anthony M

2013-03-01

ERCC1 (excision repair cross-complementation group 1) expression has been shown to be a molecular marker of cisplatin resistance in many tumor sites, but has not been well studied in cervical cancer patients. The purpose of this study was to measure tumoral ERCC1 in patients with locally advanced cervical cancer treated with chemoradiation therapy (CRT) in a large multicenter cohort, and to correlate expression with clinical outcome parameters. A total of 264 patients with locally advanced cervical cancer, treated with curative-intent radical CRT from 3 major Canadian cancer centers were evaluated. Pretreatment formalin-fixed, paraffin-embedded tumor specimens were retrieved, and tissue microarrays were constructed. Tumoral ERCC1 (FL297 antibody) was measured using AQUA (R) technology. Statistical analysis was performed to determine the significance of clinical factors and ERCC1 status with progression-free survival (PFS) and overall survival (OS) at 5 years. The majority of patients had International Federation of Gynecology and Obstetrics (FIGO) stage II disease (n=119, 45%); median tumor size was 5 cm. OS was associated with tumor size (HR 1.16, P=.018), pretreatment hemoglobin status (HR 2.33, P=.00027), and FIGO stage. In addition, tumoral ERCC1 status (nuclear to cytoplasmic ratio) was associated with PFS (HR 2.33 [1.05-5.18], P=.038) and OS (HR 3.13 [1.27-7.71], P=.013). ERCC1 status was not significant on multivariate analysis when the model was adjusted for the clinical factors: for PFS (HR 1.49 [0.61-3.6], P=.38); for OS (HR 2.42 [0.94-6.24] P=.067). In this large multicenter cohort of locally advanced cervical cancer patients treated with radical CRT, stage, tumor size, and pretreatment hemoglobin status were significantly associated with PFS and OS. ERCC1 status appears to have prognostic impact on univariate analysis in these patients, but was not independently associated with outcome on multivariate analysis. Copyright © 2013. Published by Elsevier

The Significance of Tumoral ERCC1 Status in Patients With Locally Advanced Cervical Cancer Treated With Chemoradiation Therapy: A Multicenter Clinicopathologic Analysis

Energy Technology Data Exchange (ETDEWEB)

Doll, Corinne M., E-mail: Corinne.Doll@albertahealthservices.ca [Department of Oncology, University of Calgary, Calgary, AB (Canada); Aquino-Parsons, Christina [Department of Radiation Oncology, University of British Columbia, Vancouver, BC (Canada); Pintilie, Melania [Department of Biostatistics, Ontario Cancer Institute/Princess Margaret Hospital, University of Toronto, Toronto, ON (Canada); Klimowicz, Alexander C. [Department of Oncology, University of Calgary, Calgary, AB (Canada); Petrillo, Stephanie K. [Department of Pathology, University of Calgary, Calgary, AB (Canada); Milosevic, Michael [Department of Radiation Oncology, University Health Network, University of Toronto, Toronto, ON (Canada); Craighead, Peter S. [Department of Oncology, University of Calgary, Calgary, AB (Canada); Clarke, Blaise [Department of Pathology, University of Toronto, Toronto, ON (Canada); Lees-Miller, Susan P. [Departments of Biochemistry and Molecular Biology, and Oncology, University of Calgary, Calgary, AB (Canada); Fyles, Anthony W. [Department of Radiation Oncology, University Health Network, University of Toronto, Toronto, ON (Canada); Magliocco, Anthony M. [Department of Pathology, Lee Moffitt Cancer Center, Tampa, Florida (United States)

2013-03-01

Purpose: ERCC1 (excision repair cross-complementation group 1) expression has been shown to be a molecular marker of cisplatin resistance in many tumor sites, but has not been well studied in cervical cancer patients. The purpose of this study was to measure tumoral ERCC1 in patients with locally advanced cervical cancer treated with chemoradiation therapy (CRT) in a large multicenter cohort, and to correlate expression with clinical outcome parameters. Methods and Materials: A total of 264 patients with locally advanced cervical cancer, treated with curative-intent radical CRT from 3 major Canadian cancer centers were evaluated. Pretreatment formalin-fixed, paraffin-embedded tumor specimens were retrieved, and tissue microarrays were constructed. Tumoral ERCC1 (FL297 antibody) was measured using AQUA (R) technology. Statistical analysis was performed to determine the significance of clinical factors and ERCC1 status with progression-free survival (PFS) and overall survival (OS) at 5 years. Results: The majority of patients had International Federation of Gynecology and Obstetrics (FIGO) stage II disease (n=119, 45%); median tumor size was 5 cm. OS was associated with tumor size (HR 1.16, P=.018), pretreatment hemoglobin status (HR 2.33, P=.00027), and FIGO stage. In addition, tumoral ERCC1 status (nuclear to cytoplasmic ratio) was associated with PFS (HR 2.33 [1.05-5.18], P=.038) and OS (HR 3.13 [1.27-7.71], P=.013). ERCC1 status was not significant on multivariate analysis when the model was adjusted for the clinical factors: for PFS (HR 1.49 [0.61-3.6], P=.38); for OS (HR 2.42 [0.94-6.24] P=.067). Conclusions: In this large multicenter cohort of locally advanced cervical cancer patients treated with radical CRT, stage, tumor size, and pretreatment hemoglobin status were significantly associated with PFS and OS. ERCC1 status appears to have prognostic impact on univariate analysis in these patients, but was not independently associated with outcome on

The Significance of Tumoral ERCC1 Status in Patients With Locally Advanced Cervical Cancer Treated With Chemoradiation Therapy: A Multicenter Clinicopathologic Analysis

International Nuclear Information System (INIS)

Doll, Corinne M.; Aquino-Parsons, Christina; Pintilie, Melania; Klimowicz, Alexander C.; Petrillo, Stephanie K.; Milosevic, Michael; Craighead, Peter S.; Clarke, Blaise; Lees-Miller, Susan P.; Fyles, Anthony W.; Magliocco, Anthony M.

2013-01-01

Purpose: ERCC1 (excision repair cross-complementation group 1) expression has been shown to be a molecular marker of cisplatin resistance in many tumor sites, but has not been well studied in cervical cancer patients. The purpose of this study was to measure tumoral ERCC1 in patients with locally advanced cervical cancer treated with chemoradiation therapy (CRT) in a large multicenter cohort, and to correlate expression with clinical outcome parameters. Methods and Materials: A total of 264 patients with locally advanced cervical cancer, treated with curative-intent radical CRT from 3 major Canadian cancer centers were evaluated. Pretreatment formalin-fixed, paraffin-embedded tumor specimens were retrieved, and tissue microarrays were constructed. Tumoral ERCC1 (FL297 antibody) was measured using AQUA (R) technology. Statistical analysis was performed to determine the significance of clinical factors and ERCC1 status with progression-free survival (PFS) and overall survival (OS) at 5 years. Results: The majority of patients had International Federation of Gynecology and Obstetrics (FIGO) stage II disease (n=119, 45%); median tumor size was 5 cm. OS was associated with tumor size (HR 1.16, P=.018), pretreatment hemoglobin status (HR 2.33, P=.00027), and FIGO stage. In addition, tumoral ERCC1 status (nuclear to cytoplasmic ratio) was associated with PFS (HR 2.33 [1.05-5.18], P=.038) and OS (HR 3.13 [1.27-7.71], P=.013). ERCC1 status was not significant on multivariate analysis when the model was adjusted for the clinical factors: for PFS (HR 1.49 [0.61-3.6], P=.38); for OS (HR 2.42 [0.94-6.24] P=.067). Conclusions: In this large multicenter cohort of locally advanced cervical cancer patients treated with radical CRT, stage, tumor size, and pretreatment hemoglobin status were significantly associated with PFS and OS. ERCC1 status appears to have prognostic impact on univariate analysis in these patients, but was not independently associated with outcome on

Iron nutrition and premenopausal women: effects of poor iron status on physical and neuropsychological performance.

Science.gov (United States)

McClung, James P; Murray-Kolb, Laura E

2013-01-01

Iron is a nutritionally essential trace element that functions through incorporation into proteins and enzymes, many of which contribute to physical and neuropsychological performance. Poor iron status, including iron deficiency (ID; diminished iron stores) and iron deficiency anemia (IDA; poor iron stores and diminished hemoglobin), affects billions of people worldwide. This review focuses on physical and neuropsychological outcomes associated with ID and IDA in premenopausal women, as the prevalence of ID and IDA is often greater in premenopausal women than other population demographics. Recent studies addressing the physiological effects of poor iron status on physical performance, including work productivity, voluntary activity, and athletic performance, are addressed. Similarly, the effects of iron status on neurological performance, including cognition, affect, and behavior, are summarized. Nutritional countermeasures for the prevention of poor iron status and the restoration of decrements in performance outcomes are described.

Exposing the {010} Planes by Oriented Self-Assembly with Nanosheets To Improve the Electrochemical Performances of Ni-Rich Li[Ni0.8Co0.1Mn0.1]O2 Microspheres.

Science.gov (United States)

Su, Yuefeng; Chen, Gang; Chen, Lai; Li, Weikang; Zhang, Qiyu; Yang, Zhiru; Lu, Yun; Bao, Liying; Tan, Jing; Chen, Renjie; Chen, Shi; Wu, Feng

2018-02-21

A modified Ni-rich Li[Ni 0.8 Co 0.1 Mn 0.1 ]O 2 cathode material with exposed {010} planes is successfully synthesized for lithium-ion batteries. The scanning electron microscopy images have demonstrated that by tuning the ammonia concentration during the synthesis of precursors, the primary nanosheets could be successfully stacked along the [001] crystal axis predominantly, self-assembling like multilayers. According to the high-resolution transmission electron microscopy results, such a morphology benefits the growth of the {010} active planes of final layered cathodes during calcination treatment, resulting in the increased area of the exposed {010} active planes, a well-ordered layer structure, and a lower cation mixing disorder. The Li-ion diffusion coefficient has also been improved after the modification based on the results of potentiostatic intermittent titration technique. As a consequence, the modified Li[Ni 0.8 Co 0.1 Mn 0.1 ]O 2 material exhibits superior initial discharges of 201.6 mA h g -1 at 0.2 C and 185.7 mA h g -1 at 1 C within 2.8-4.3 V (vs Li + /Li), and their capacity retentions after 100 cycles reach 90 and 90.6%, respectively. The capacity at 10 C also increases from 98.3 to 146.5 mA h g -1 after the modification. Our work proposes a novel approach for exposing high-energy {010} active planes of the layered cathode material and again confirms its validity in improving electrochemical properties.

Magnetic and transport properties of Cu1.05Cr0.89 Mg0.05O2 and Cu0.96Cr0.95 Mg0.05Mn0.04O2 films

International Nuclear Information System (INIS)

Xu Qingyu; Schmidt, Heidemarie; Zhou Shengqiang; Potzger, Kay; Helm, Manfred; Hochmuth, Holger; Lorenz, Michael; Meinecke, Christoph; Grundmann, Marius

2008-01-01

We prepared conductive, polycrystalline or amorphous Cu 1.05 Cr 0.89 Mg 0.05 O 2 films on a-plane sapphire substrates by pulsed laser deposition under different O 2 partial pressure and substrate temperature. Hall measurements were performed to study the majority carrier type in these films. Polycrystalline Cu 1.05 Cr 0.89 Mg 0.05 O 2 is n-type conducting at 290 K, while in amorphous Cu 1.05 Cr 0.89 Mg 0.05 O 2 the type of majority charge carriers changes from electrons to holes at around 270 K. Interestingly, the structure has little influence on the magnetic properties of the films. A clear antiferromagnetic to paramagnetic transition was observed in both polycrystalline and amorphous Cu 1.05 Cr 0.89 Mg 0.05 O 2 films at 25 K. Similar electrical properties to Cu 1.05 Cr 0.89 Mg 0.05 O 2 film were observed for Cu 0.96 Cr 0.95 Mg 0.05 Mn 0.04 O 2 in dependence on the structure, while only paramagnetic without antiferromagnetic ordering was observed down to 5 K. Large negative magnetoresistance of 27% at 20 K was observed at 6 T in amorphous Cu 1.05 Cr 0.89 Mg 0.05 O 2 film

Rational choice of a minimally invasive method of treatment in uncomplicated nephrolithiasis with kidney calculi from 1.0 to 2.5 cm

Directory of Open Access Journals (Sweden)

А. І. Sagalevich

2018-02-01

Full Text Available Study purpose – to improve the solitary nephrolithiasis treatment effectiveness by determining the optimal conditions for ESWL or mini PNL application in the treatment of kidney calculi 1.0 to2.5 cm in size. Patients and methods. A comparative analysis of the results of minimally invasive methods application for nephrolithiasis treatment was performed in 210 patients treated with mini PNL (the group I and 190 patients treated with ESWL (the group II. Patients with calculi more than 1.5 cm predominated in the group of mini PNL and with calculi less than 1.5 cm – in the ESWL group. The number of patients with calculi 1.5–2.0 cm in both groups was the same: 24.3 % and 24.2 % (P > 0.05. Results. It was noted that the calculi destruction effectiveness after 1–4 or more sessions of ESWL took place in 182 patients (95.8 %. At the same time, an increase in the mean density of calculi above 600 HU caused reduction (P < 0.001 of the primary ESWL session efficiency almost twofold. When performing the 221 mPNL, 97.1 % of the patients required one surgical treatment. The number of complications (bleeding, attack of pyelonephritis in the group II was insignificantly higher in contrast to the group I – 26 (12.3 % and 45 (14.1 %, respectively (P < 0.05. The stone-free status (up to one month was noted in 62.6 % of patients after the completion of ESWL sessions that increases the risk of nephrolithiasis recurrence from 37.4 %. In treatment with mPNL, the stone-free status reached 97.1 % (P < 0.001, and in repeated mPNL applying in 2.8 % of cases – 100 %. The mean clinic postoperative treatment periods in the group I were lower in contrast to patients of the group II – 3.0 ± 1.5 and 12.5 ± 3.6, respectively (P < 0.001. Conclusions. This comparative analysis of features and results of uncomplicated nephrolithiasis with mPNL and ESWL treatment indicates that mPNL is the most preferred method for kidney calculi 1.0 to2.5 cm and more in size treatment.

Time of Day and Training Status Both Impact the Efficacy of Caffeine for Short Duration Cycling Performance

Directory of Open Access Journals (Sweden)

James C. Boyett

2016-10-01

Full Text Available This project was designed to assess the effects of time of day and training status on the benefits of caffeine supplementation for cycling performance. Twenty male subjects (Age, 25 years; Peak oxygen consumption, 57 mL·kg−1·min−1 were divided into tertiles based on training levels, with top and bottom tertiles designated as ‘trained’ (n = 7 and ‘untrained’ (n = 7. Subjects completed two familiarization trials and four experimental trials consisting of a computer-simulated 3-km cycling time trial (TT. The trials were performed in randomized order for each combination of time of day (morning and evening and treatment (6mg/kg of caffeine or placebo. Magnitude-based inferences were used to evaluate all treatment effects. For all subjects, caffeine enhanced TT performance in the morning (2.3% ± 1.7%, ‘very likely’ and evening (1.4% ± 1.1%, ‘likely’. Both untrained and trained subjects improved performance with caffeine supplementation in the morning (5.5% ± 4.3%, ‘likely’; 1.0% ± 1.7%, ‘likely’, respectively, but only untrained subjects rode faster in the evening (2.9% ± 2.6%, ‘likely’. Altogether, our observations indicate that trained athletes are more likely to derive ergogenic effects from caffeine in the morning than the evening. Further, untrained individuals appear to receive larger gains from caffeine in the evening than their trained counterparts.

GStat 2.0: Grid Information System Status Monitoring

CERN Document Server

Field, L; Tsai, M; CERN. Geneva. IT Department

2010-01-01

Grid Information Systems are mission-critical components in today's production grid infrastructures. They enable users, applications and services to discover which services exist in the infrastructure and further information about the service structure and state. It is therefore important that the information system components themselves are functioning correctly and that the information content is reliable. Grid Status (GStat) is a tool that monitors the structural integrity of the EGEE information system, which is a hierarchical system built out of more than 260 site-level and approximately 70 global aggregation services. It also checks the information content and presents summary and history displays for Grid Operators and System Administrators. A major new version, GStat 2.0, aims to build on the production experience of GStat and provides additional functionality, which enables it to be extended and combined with other tools

Electrochemical performance of LiNi0.5Mn1.5O4 prepared by improved solid state method as cathode in hybrid supercapacitor

International Nuclear Information System (INIS)

Wu Huiming; Rao, Ch. Venkateswara; Rambabu, B.

2009-01-01

The electrochemical performance of a hybrid asymmetric supercapacitor with activated carbon (AC) as anode and a lithium-ion intercalated compound LiNi 0.5 Mn 1.5 O 4 as cathode was studied. By using metal acetate precursors as starting materials in solid state reaction method, pure LiNi 0.5 Mn 1.5 O 4 was formed at low temperature. The role of precursors on the formation of material at low temperature and short period of time is presented. XRD confirms the cubic spinel structure (space group, Fd3m) and SEM shows the particles of size around 1 μm. The effect of the modified solid state reaction route on the structural and electrochemical properties was investigated. The fabricated hybrid supercapacitor, AC/LiNi 0.5 Mn 1.5 O 4 in a non-aqueous electrolyte 1.0 M LiPF 6 /EC-DMC exhibits a sloping voltage profile from 1.0 to 3.0 V and delivers a specific energy of ca. 56 Wh kg -1 . Moreover, it exhibits excellent cycling performance with less than 5% capacity loss over 1000 cycles.

Development of DUO-THERM Ver 1.0

Energy Technology Data Exchange (ETDEWEB)

Yang, Yong Sik; Chun, Tae Hyun; Shin, Chang Hwan; Song, Kun Woo

2008-10-15

DUO{sub T}HERM ver 1.0 program was developed which can evaluate a double cooled annular fuel thermal behavior. This program can analyze a fuel thermal performance such as a fuel temperature and thermal expansion based upon the evaluated results of flow and heat split which are special features of double cooled annular pellet. By using the sample input data, a preliminary calculation was performed and showed that DUO-THERM ver 1.0 can be applicable for prediction of the fuel temperature, heat and flow split and thermal deformation. For the verification of DUO program, the flow split, heat split, maximum fuel temperature, maximum temperature location and fuel thermal conductivity were compared with MATRA-AF results which was calculated under same input variables and showed good agreement with each other.

Role of Ag-alloy in the thermal stability of Ag-based ohmic contact to GaN(0 0 0 1) surface

International Nuclear Information System (INIS)

Xiong, Zhihua; Qin, Zhenzhen; Zhao, Qian; Chen, Lanli

2015-01-01

First-principles calculations are performed to study Ag and Ag-alloy adsorption stability on GaN(0 0 0 1) surface. We find Ag only contact to GaN surface is unstable under high temperature. While Ag-alloy adsorption exhibits better adsorption stability and electronic properties than that of the Ag only contact,due to the enhanced interaction between Ag-alloy and GaN(0 0 0 1) surface. The Ag-alloy, particularly AgNi, is proposed to be used as very promising ohmic contact to GaN for practical applications

Adhesion and fracture toughness at α-Ti(0 0 0 1)/TiC(1 1 1): A first-principles investigation

International Nuclear Information System (INIS)

Li, Jian; Yang, Yanqing; Feng, Guanghai; Luo, Xian; Sun, Qing; Jin, Na

2013-01-01

The interfacial properties of α-Ti(0 0 0 1)/TiC(1 1 1) interface, such as adhesion, interface energy, interfacial fracture toughness, bonding nature, are investigated using first-principles calculations. Six interface models with different TiC(1 1 1) termination and stacking sites are investigated to clarify their influence on the interfacial stability and adhesion strength. C-terminated-hollow-site and Ti-terminated-center-site models exhibit identical epitaxial stacking style after fully relaxation, and can be regarded as the Ti and TiC sides of the most stable and strongest interface. The possible negative interface energy indicates the interfacial diffusion, and even new phase formation, is likely to happen across the interface. The largest interfacial fracture toughness is estimated about 4.8 MPa m 1/2 . The valence electron density and partial density of states (PDOS) indicate that its interfacial bonding is mainly contributed from C-Ti covalent bonds and Ti-Ti metallic interaction.

STATUS BERKELANJUTAN KOTA TANGERANG SELATAN-BANTEN DENGAN MENGGUNAKAN KEY PERFORMANCE INDICATORS (Sustainable Status of South Tangerang City-Banten Using Key Performance Indicators

Directory of Open Access Journals (Sweden)

Heri Apriyanto

2015-07-01

Full Text Available ABSTRAK Pembangunan kota yang tidak terkendali akan mengakibatkan tekanan terhadap lingkungan dan beban masyarakat meningkat, sebaliknya degradasi lingkungan akan mengakibatkan pembatasan pengembangan ekonomi dan penurunan kualitas hidup. Guna mencegah terjadinya dampak-dampak negatif, maka diperlukan prinsip-prinsip pembangunan kota yang berkelanjutan. Evaluasi terhadap pelaksanan pembangunan kota yang berkelanjutan perlu dilakukan untuk mengetahui apakah pembangunan suatu kota sudah atau belum/tidak berkelanjutan. Penelitian ini bertujuan untuk menyusun Key Performance Indicators (KPI guna menilai status pembangunan kota berkelanjutan. Perumusan KPI ini dilakukan dengan pendekatan Analytic Hierarchy Process (AHP. KPI yang dihasilkan terdiri dari 21 indikator dan 9 elemen dari 3 pilar pembangunan berkelanjutan (ekonomi, sosial, dan lingkungan. Implementasi KPI dilakukan untuk pengukuran status keberlanjutan Kota Tangerang Selatan. Hasil pengukuran menunjukkan bahwa kota ini termasuk dalam tahap awal pembangunan berkelanjutan. Secara umum perkembangan ekonomi dan sosial relatif cukup baik, namun tidak demikian dengan kondisi lingkungannya. ABSTRACT Uncontrolled urban development will result in pressure on the environment and the burden of the people. On the contrary, environmental degradation will lead to restricted economic development and decreased quality of life. In order to prevent negative impacts, it is necessary to implement the principles of sustainable city development. Evaluation of the implementation of sustainable city development is needed to determine whether the development of a city is sustainable or not. This study aimed to develop Key Performance Indicators (KPI to assess the status of sustainable city development. The formulation of KPI is done with Analytic Hierarchy Process (AHP. KPI generated consists of 21 indicators and 9 elements of the 3 pillars of sustainable development (economic, social, and environmental

The National Ignition Facility 2007 laser performance status

Energy Technology Data Exchange (ETDEWEB)

Haynam, C A; Sacks, R A; Wegner, P J; Bowers, M W; Dixit, S N; Erbert, G V; Heestand, G M; Henesian, M A; Hermann, M R; Jancaitis, K S; Manes, K R; Marshall, C D; Mehta, N C; Menapace, J; Nostrand, M C; Orth, C D; Shaw, M J; Sutton, S B; Williams, W H; Widmayer, C C [Lawrence Livermore National Laboratory, 7000 East Avenue, Livermore, CA, 94550 (United States)], E-mail: haynam1@llnl.gov (and others)

2008-05-15

The National Ignition Facility (NIF) at Lawrence Livermore National Laboratory contains a 192-beam 3.6 MJ neodymium glass laser that is frequency converted to 351nm light. It has been designed to support high energy density science (HEDS), including the demonstration of fusion ignition through Inertial Confinement. To meet this goal, laser design criteria include the ability to generate pulses of up to 1.8-MJ total energy at 351nm, with peak power of 500 TW and precisely-controlled temporal pulse shapes spanning two orders of magnitude. The focal spot fluence distribution of these pulses is conditioned, through a combination of special optics in the 1{omega} (1053 nm) portion of the laser (continuous phase plates), smoothing by spectral dispersion (SSD), and the overlapping of multiple beams with orthogonal polarization (polarization smoothing). In 2006 and 2007, a series of measurements were performed on the NIF laser, at both 1{omega} and 3{omega} (351 nm). When scaled to full 192-beam operation, these results lend confidence to the claim that NIF will meet its laser performance design criteria and that it will be able to simultaneously deliver the temporal pulse shaping, focal spot conditioning, peak power, shot-to-shot reproducibility, and power balance requirements of indirect-drive fusion ignition campaigns. We discuss the plans and status of NIF's commissioning, and the nature and results of these measurement campaigns.

Precipitation hardening of Zn0.1 at.%Ti single crystals deformed on the (0 0 0 1) system

International Nuclear Information System (INIS)

Boczkal, G.; Mikulowski, B.

2004-01-01

The mechanical properties (the critical resolved shear stress - CRSS, the work-hardening coefficient - θ A ) and a thermodynamic parameter (the activation volume--V*) have been studied in single crystals of Zn0.1 at.%Ti. The sample orientation allowed slip on the (0 0 0 1) system over a large range of strain. The investigations were conducted on samples which were both heat treated and not. The investigations were made using compression and stress relaxation tests in the range of easy glide at temperatures from 77 to 493 K. The single crystals appear to be hardened by precipitates while Ti solubility in Zn is negligible. Two types of the precipitates have been identified by TEM and microanalysis; very small precipitates were located uniformly in the matrix, and large needle-shaped obstacles with size of the order of 0.1 mm on the (0 0 0 1) orientation. The CRSS and the θ A showed a strong dependence on the temperature. The determined values of the CRSS were in the range of 4 MPa for 493 K to 12 MPa for 77 K. The obtained values of the activation volume V* were in the range of (10-110) x 10 -16 cm 3 and it was strongly dependent on the temperature and the stress at the beginning of relaxation. This value is attributed to small precipitates which are barriers for dislocation movement

Subsets of microsatellite-unstable colorectal cancers exhibit discordance between the CpG island methylator phenotype and MLH1 methylation status.

Science.gov (United States)

Kim, Jung H; Rhee, Ye-Y; Bae, Jeong-M; Kwon, Hyeong-J; Cho, Nam-Y; Kim, Mi J; Kang, Gyeong H

2013-07-01

Although the presence of MLH1 methylation in microsatellite-unstable colorectal cancer generally indicates involvement of the CpG island methylator phenotype (CIMP) in the development of the tumor, these two conditions do not always correlate. A minority of microsatellite-unstable colorectal cancers exhibit discordance between CIMP and MLH1 methylation statuses. However, the clinicopathological features of such microsatellite-unstable colorectal cancers with discrepant MLH1 methylation and CIMP statuses remain poorly studied. Microsatellite-unstable colorectal cancers (n=220) were analyzed for CIMP and MLH1 methylation statuses using the MethyLight assay. Based on the combinatorial CIMP and MLH1 methylation statuses, the microsatellite-unstable colorectal cancers were grouped into four subtypes (CIMP-high (CIMP-H) MLH1 methylation-positive (MLH1m+), CIMP-H MLH1 methylation-negative, CIMP-low/0 (CIMP-L/0) MLH1m+, and CIMP-L/0 MLH1 methylation-negative), which were compared in terms of their associations with clinicopathological and molecular features. The CIMP-L/0 MLH1 methylation-negative and CIMP-H MLH1m+ subtypes were predominant, comprising 63.6 and 24.1% of total microsatellite-unstable colorectal cancers, respectively. The discordant subtypes, CIMP-H MLH1 methylation-negative and CIMP-L/0 MLH1m+, were found in 5 and 7% of microsatellite-unstable colorectal cancers, respectively. The CIMP-H MLH1 methylation-negative subtype exhibited elevated incidence rates in male patients and was associated with larger tumor size, more frequent loss of MSH2 expression, increased frequency of KRAS mutation, and advanced cancer stage. The CIMP-L/0 MLH1m+ subtype was associated with onset at an earlier age, a predominance of MLH1 loss, and earlier cancer stage. None of the CIMP-L/0 MLH1m+ subtype patients succumbed to death during the follow-up. Our findings suggest that the discordant subtypes of colorectal cancers exhibit distinct clinicopathological and molecular features

From Social Class to Self-Efficacy: Internalization of Low Social Status Pupils' School Performance

Science.gov (United States)

Wiederkehr, Virginie; Darnon, Céline; Chazal, Sébastien; Guimond, Serge; Martinot, Delphine

2015-01-01

Previous research has largely documented that socioeconomic status (SES) is a strong and consistent predictor of pupils' school performance in several countries. In this research, we argue that children internalize the SES achievement gap in the form of a lower/higher sense of school self-efficacy. In two studies, teenaged students' (Study 1) and…

Effects of Rh on the thermoelectric performance of the p-type Zr0.5Hf0.5Co1-xRhxSb0.99Sn0.01 half-Heusler alloys

International Nuclear Information System (INIS)

Maji, Pramathesh; Takas, Nathan J.; Misra, Dinesh K.; Gabrisch, Heike; Stokes, Kevin; Poudeu, Pierre F.P.

2010-01-01

We show that Rh substitution at the Co site in Zr 0.5 Hf 0.5 Co 1-x Rh x Sb 0.99 Sn 0.01 (0≤x≤1) half-Heusler alloys strongly reduces the thermal conductivity with a simultaneous, significant improvement of the power factor of the materials. Thermoelectric properties of hot-pressed pellets of several compositions with various Rh concentrations were investigated in the temperature range from 300 to 775 K. The Rh 'free' composition shows n-type conduction, while Rh substitution at the Co site drives the system to p-type semiconducting behavior. The lattice thermal conductivity of Zr 0.5 Hf 0.5 Co 1-x Rh x Sb 0.99 Sn 0.01 alloys rapidly decreased with increasing Rh concentration and lattice thermal conductivity as low as 3.7 W/m*K was obtained at 300 K for Zr 0.5 Hf 0.5 RhSb 0.99 Sn 0.01 . The drastic reduction of the lattice thermal conductivity is attributed to mass fluctuation induced by the Rh substitution at the Co site, as well as enhanced phonon scattering at grain boundaries due to the small grain size of the synthesized materials. - Graphical abstract: Significant reduction of the lattice thermal conductivity with increasing Rh concentration in the p-type Zr 0.5 Hf 0.5 Co 1-x Rh x Sb 0.99 Sn 0.01 half-Heusler materials prepared by solid state reaction at 1173 K.

A1.5 Fusion Performance

Energy Technology Data Exchange (ETDEWEB)

Amendt, P

2011-03-31

Analysis and radiation hydrodynamics simulations for expected high-gain fusion target performance on a demonstration 1-GWe Laser Inertial Fusion Energy (LIFE) power plant in the mid-2030s timeframe are presented. The required laser energy driver is 2.2 MJ at a 0.351-{micro}m wavelength, and a fusion target gain greater than 60 at a repetition rate of 16 Hz is the design goal for economic and commercial attractiveness. A scaling-law analysis is developed to benchmark the design parameter space for hohlraum-driven central hot-spot ignition. A suite of integrated hohlraum simulations is presented to test the modeling assumptions and provide a basis for a near-term experimental resolution of the key physics uncertainties on the National Ignition Facility (NIF). The NIF is poised to demonstrate ignition by 2012 based on the central hot spot (CHS) mode of ignition and propagating thermonuclear burn [1]. This immediate prospect underscores the imperative and timeliness of advancing inertial fusion as a carbon-free, virtually limitless source of energy by the mid-21st century to substantially offset fossil fuel technologies. To this end, an intensive effort is underway to leverage success at the NIF and to provide the foundations for a prototype 'LIFE.1' engineering test facility by {approx}2025, followed by a commercially viable 'LIFE.2' demonstration power plant operating at 1 GWe by {approx}2035. The current design goal for LIFE.2 is to accommodate {approx}2.2 MJ of laser energy (entering the high-Z radiation enclosure or 'hohlraum') at a 0.351-{micro}m wavelength operating at a repetition rate of 16 Hz and to provide a fusion target yield of 132 MJ. To achieve this design goal first requires a '0-d' analytic gain model that allows convenient exploration of parameter space and target optimization. This step is then followed by 2- and 3-dimensional radiation-hydrodynamics simulations that incorporate laser beam transport, x

The study of sup 1 sup 0 sup 5 Pd(n,gamma) sup 1 sup 0 sup 6 Pd reaction with thermal neutrons

CERN Document Server

Miah, M M H; Harada, H; Nakamura, S

2002-01-01

This is a report about the study of sup 1 sup 0 sup 5 Pd(n,gamma) sup 1 sup 0 sup 6 Pd reaction with thermal neutrons performed by Dr. M.M.H.Miah, who was engaged in the investigation as a visiting research associate of Japan Nuclear Cycle Development Institute (JNC) under the STA fellowship program for the periods ranging from January 2001 to July 2002, together with members belong to System Design Analysis Group of JNC. The investigation of sup 1 sup 0 sup 5 Pd(n,gamma) sup 1 sup 0 sup 6 Pd reaction has been performed by using the prompt gamma-ray spectroscopic technique to supply basic data for the nuclear transmutation. Samples of natural Pd and enriched sup 1 sup 0 sup 5 Pd were irradiated separately with the B-4 thermal neutron guide facilities at Kyoto University Research Reactor Institute (KURRI). Capture prompt gamma-rays were detected in both singles and coincidence modes by using two high purity Ge detectors. By analyzing gamma-gamma coincidence data, 42 cascading gamma-transitions were identified ...

Influence of socioeconomic status on allograft and patient survival following kidney transplantation.

Science.gov (United States)

Ward, Frank L; O'Kelly, Patrick; Donohue, Fionnuala; ÓhAiseadha, Coilin; Haase, Trutz; Pratschke, Jonathan; deFreitas, Declan G; Johnson, Howard; Conlon, Peter J; O'Seaghdha, Conall M

2015-06-01

Whether socioeconomic status confers worse outcomes after kidney transplantation is unknown. Its influence on allograft and patient survival following kidney transplantation in Ireland was examined. A retrospective, observational cohort study of adult deceased-donor first kidney transplant recipients from 1990 to 2009 was performed. Those with a valid Irish postal address were assigned a socioeconomic status score based on the Pobal Hasse-Pratschke deprivation index and compared in quartiles. Cox proportional hazards models and Kaplan-Meier survival analysis were used to investigate any significant association of socioeconomic status with patient and allograft outcomes. A total of 1944 eligible kidney transplant recipients were identified. The median follow-up time was 8.2 years (interquartile range 4.4-13.3 years). Socioeconomic status was not associated with uncensored or death-censored allograft survival (hazard ratio (HR) 1.0, 95% confidence interval (CI) 0.99-1.00, P = 0.33 and HR 1.0, 95% CI 0.99-1.00, P = 0.37, respectively). Patient survival was not associated with socioeconomic status quartile (HR 1.0, 95% CI 0.93-1.08, P = 0.88). There was no significant difference among quartiles for uncensored or death-censored allograft survival at 5 and 10 years. There was no socioeconomic disparity in allograft or patient outcomes following kidney transplantation, which may be partly attributable to the Irish healthcare model. This may give further impetus to calls in other jurisdictions for universal healthcare and medication coverage for kidney transplant recipients. © 2015 Asian Pacific Society of Nephrology.

Half-lives of isomeric levels of sup 1 sup 0 sup 7 sup m Ag, sup 1 sup 0 sup 9 sup m Ag and sup 1 sup 0 sup 3 sup m Rh photoactivated by sup 6 sup 0 Co gamma-ray irradiation

CERN Document Server

Yoshida, E; Kojima, Y; Shizuma, K

2000-01-01

Photoactivation by gamma-rays from sup 6 sup 0 Co of 10 kCi has been performed for isomers of sup 1 sup 0 sup 7 sup m Ag, sup 1 sup 0 sup 9 sup m Ag and sup 1 sup 0 sup 3 sup m Rh and half-lives of these isomers were determined. Gamma-rays emitted from sup 1 sup 0 sup 7 sup m Ag and sup 1 sup 0 sup 9 sup m Ag were measured with a low-background Ge detector and internal conversion electrons from sup 1 sup 0 sup 3 sup m Rh were measured with a 2 pi gas flow counter. The half-lives obtained are: sup 1 sup 0 sup 7 sup m Ag: 44.5+-0.8 s, sup 1 sup 0 sup 9 sup m Ag: 38.0+-1.2 s and sup 1 sup 0 sup 3 sup m Rh: 54.8+-3.8 min. The results are in agreement with previous values obtained by different excitation methods.

Methodology of the Integrated Analysis of Company's Financial Status and Its Performance Results

OpenAIRE

Mackevičius, Jonas; Valkauskas, Romualdas

2010-01-01

Information about company's financial status and its performance results is very important for the objective evaluation of company's position in the market and competitive possibilities in the future. Such information is provided in the financial statement. It is important to apply and investigate this information properly. The methodology of company's financial status and performance results integrated analysis is recommended in this article. This methodology consists of these three elements...

LLCEDATA and LLCECALC for Windows version 1.0, Volume 1: User`s manual

Energy Technology Data Exchange (ETDEWEB)

McFadden, J.G.

1998-09-04

LLCEDATA and LLCECALC for Windows are user-friendly computer software programs that work together to determine the proper waste designation, handling, and disposition requirements for Long Length Contaminated Equipment (LLCE). LLCEDATA reads from a variety of data bases to produce an equipment data file (EDF) that represents a snapshot of both the LLCE and the tank it originates from. LLCECALC reads the EDF and a gamma assay (AV2) file that is produced by the Flexible Receiver Gamma Energy Analysis System. LLCECALC performs corrections to the AV2 file as it is being read and characterizes the LLCE. Both programs produce a variety of reports, including a characterization report and a status report. The status report documents each action taken by the user, LLCEDATA, and LLCECALC. Documentation for LLCEDATA and LLCECALC for Windows is available in three volumes. Volume 1 is a user`s manual, which is intended as a quick reference for both LLCEDATA and LLCECALC. Volume 2 is a technical manual, and Volume 3 is a software verification and validation document.

Sensitivity of mitochondrial DNA depleted ρ0 cells to H2O2 depends on the plasma membrane status.

Science.gov (United States)

Tomita, Kazuo; Kuwahara, Yoshikazu; Takashi, Yuko; Tsukahara, Takao; Kurimasa, Akihiro; Fukumoto, Manabu; Nishitani, Yoshihiro; Sato, Tomoaki

2017-08-19

To clarify the relationship between mitochondrial DNA (mtDNA)-depleted ρ0 cells and the cellular sensitivity to hydrogen peroxide (H 2 O 2 ), we established HeLa and SAS ρ0 cell lines and investigated their survival rate in H 2 O 2 , radical scavenging enzymes, plasma membrane potential status, and chronological change in intracellular H 2 O 2 amount under the existence of extracellular hydrogen peroxide compared with the parental cells. The results revealed that ρ0 cells had higher sensitivity to H 2 O 2 than their parental cells, even though the catalase activity of ρ0 cells was up-regulated, and the membrane potential of the ρ0 cells was lower than their parental cells. Furthermore, the internal H 2 O 2 amount significantly increased only in ρ0 cells after 50 μM H 2 O 2 treatment for 1 h. These results suggest that plasma membrane status of ρ0 cells may cause degradation, and the change could lead to enhanced membrane permeability to H 2 O 2 . As a consequence, ρ0 cells have a higher H 2 O 2 sensitivity than the parental cells. Copyright © 2017 Elsevier Inc. All rights reserved.

Towards Culture 3.0 - Performative space in the public library

DEFF Research Database (Denmark)

Jochumsen, Henrik; Skot-Hansen, Dorte; Rasmussen, Casper Hvenegaard

2015-01-01

The aim of this article is to analyse and discuss the development of performative spaces in public libraries from a cultural policy perspective. First, a framework of three concepts of culture, 1.0–3.0, is used as a tool to analyse the overall development of public libraries. Against...... this background, we introduce the notion of performative spaces in public libraries by highlighting Nordic examples. The tendency can also be seen on a broader level in European and North American libraries, where a ‘performative turn’ can be seen as the relationship between the library and its users, especially...... the younger ‘digital natives’. The rationales behind the emergence of performative spaces in public libraries are analysed and discussed: democratisation, empowerment and economic impact. This article concludes that the performative spaces are legitimized by multiple rationales in the same way as cultural...

Oxygen transport in La0.6Sr0.4Co1-yFeyO3-d

NARCIS (Netherlands)

Bouwmeester, Henricus J.M.; den Otter, M.W.; Boukamp, Bernard A.

2004-01-01

The surface exchange coefficient and chemical diffusion coefficient of oxygen for the perovskites La0.6Sr0.4Co1–yFeyO3–delta (y=0.2, 0.5 and 0.8) were measured using the conductivity relaxation technique. Measurements were performed between 600 and 800 °C in an oxygen partial pressure range between

Effect of A-site deficiency in LaMn{sub 0.9}Co{sub 0.1}O{sub 3} perovskites on their catalytic performance for soot combustion

Energy Technology Data Exchange (ETDEWEB)

Dinamarca, Robinson [Department of Physical Chemistry, Faculty of Chemical Sciences, University of Concepción, Concepción (Chile); Garcia, Ximena; Jimenez, Romel [Department of Chemical Engineering, Faculty of Engineering, University of Concepción, Concepción (Chile); Fierro, J.L.G. [Instituto de Catálisis y Petroleoquímica, CSIC, Cantoblanco, 28049 Madrid (Spain); Pecchi, Gina, E-mail: gpecchi@udec.cl [Department of Physical Chemistry, Faculty of Chemical Sciences, University of Concepción, Concepción (Chile)

2016-09-15

Highlights: • A-site defective perovskites increases the oxidation state of the B-cation. • Not always non-stoichiometric perovskites exhibit higher catalytic activity in soot combustion. • The highly symmetric cubic crystalline structure diminishes the redox properties of perovskites. - Abstract: The influence of lanthanum stoichiometry in Ag-doped (La{sub 1-x}Ag{sub x}Mn{sub 0.9}Co{sub 0.1}O{sub 3}) and A-site deficient (La{sub 1-x}Mn{sub 0.9}Co{sub 0.1}O{sub 3-δ}) perovskites with x equal to 10, 20 and 30 at.% has been investigated in catalysts for soot combustion. The catalysts were prepared by the amorphous citrate method and characterized by XRD, nitrogen adsorption, XPS, O{sub 2}-TPD and TPR. The formation of a rhombohedral excess-oxygen perovskite for Ag-doped and a cubic perovskite structure for an A-site deficient series is confirmed. The efficient catalytic performance of the larger Ag-doped perovskite structure is attributed to the rhombohedral crystalline structure, Ag{sub 2}O segregated phases and the redox pair Mn{sup 4+}/Mn{sup 3+}. A poor catalytic activity for soot combustion was observed with A-site deficient perovskites, despite the increase in the redox pair Mn{sup 4+}/Mn{sup 3+}, which is attributed to the cubic crystalline structure.

Performance Comparison of 1.5 T Endorectal Coil MRI with Non-Endorectal Coil 3.0 T MRI in Patients with Prostate Cancer

Science.gov (United States)

Shah, Zarine K.; Elias, Saba N.; Abaza, Ronney; Zynger, Debra L.; DeRenne, Lawrence A.; Knopp, Michael V.; Guo, Beibei; Schurr, Ryan; Heymsfield, Steven B.; Jia, Guang

2015-01-01

Rationale and Objectives To compare prostate morphology, image quality, and diagnostic performance of 1.5 T endorectal coil MRI and 3.0 T non-endorectal coil MRI in patients with prostate cancer. Materials and Methods MR images obtained of 83 patients with prostate cancer using 1.5 T MRI systems with an endorectal coil were compared to images collected from 83 patients with a 3.0 T MRI system. Prostate diameters were measured and image quality was evaluated by one ABR-certified radiologist (Reader 1) and one ABR-certified diagnostic medical physicist (Reader 2). The likelihood of the peripheral zone cancer presence in each sextant and local extent were rated and compared with histopathologic findings. Results Prostate anterior-posterior diameter measured by both readers was significantly shorter with 1.5 T endorectal MRI than with 3.0 T MRI. The overall image quality score difference was significant only for Reader 1. Both readers found that the two MRI systems provided similar diagnostic accuracy in cancer localization, extraprostatic extension, and seminal vesicle involvement. Conclusion Non-endorectal coil 3.0 T MRI provides prostate images that are natural in shape and that have comparable image quality to those obtained at 1.5 T with an endorectal coil, but not superior diagnostic performance. These findings suggest an opportunity exists for improving technical aspects of 3.0 T prostate MRI. PMID:25579637

The Relationship Between Mental State and Functional Status in Elderly Residents of Kahrizak

Directory of Open Access Journals (Sweden)

Hadi Kazemi

2010-03-01

Full Text Available Objectives: The current study was performed to investigate the relationship between mental impairment and each component of activity of daily living (ADL in elderly residents of the Kahrizak Charity Foundation. Methods & Materials: Standardized Iranian Mini Mental examination and Barthel index were used to assest cognitive status and ADL in 184 elderly residents of Kahrizak, respectively. Results: Data showed that 31.7% of participants had normal cognitive status and 63.3% had cognitive impairment. There was significant relationship between cognitive status and ADL after adjustment for confounding factors (P=0.01, r=0.2. By using multiple logistic regression analysis, the relation between cognitive impairment and functional status was examined (P=0.05. Odd ratio of functional disability showed an increasing trend with increasing severity of cognitive impairment [Odd Ratio (OR mild cognitive impairment: 1.13, Confidence Interval (CI: 0.54-2.37 OR moderate to severe cognitive impairment: 3.67, CI: 0.39-34.35]. Regarding the relation between Barthel components and cognitive status it was showed that there was a significant association between independent bathing and cognitive status (OR: 2.33, CI: 1.14-4.72 as well as movementability with cognitive impairment (OR: 2.96, CI: 1.30-6.75. Conclusion: Cognitive status can be a predictive factor of ADL inelderly subjects.

the relationship of birth status and early reproductive performance ...

African Journals Online (AJOL)

The effectiveness of selection for improvement in reproductive performance of sheep depends on measure- ment at any early age. For this reason selection of rams and ewes on their birth status, (single or twin), (Kennedy,. 1967; Turner, Hayman, Triffitt and Prunster, 1969), and ewes having multiple births during their first or ...

Perovskite oxides La0.4Sr0.6CoxMn1-xO3 (x = 0, 0.2, 0.4 as an effective electrocatalyst for lithium—air batteries

Directory of Open Access Journals (Sweden)

Yajun Zhao

2018-01-01

Full Text Available Co-doped perovskite oxide La0.4Sr0.6CoxMn1-xO3 (x = 0, 0.2, 0.4 composites are prepared by sol–gel method utilizing citric acid as chelating agent. These composites show good catalytic activities when tested as catalysts rechargeable lithium—air batteries. In particular, the La0.4Sr0.6Co0.4Mn0.6O3 shows a lower potential gap. When these samples are tested as catalysts for Li—air batteries at a current density of 100 mA g−1, the discharge capacities with different La0.4Sr0.6CoxMn1-xO3 (x = 0, 0.2, 0.4 catalysts are 5819, 6420, and 7227 mA h g−1, respectively. In addition, under a capacity limitation of 1000 mA h g−1, the cell using La0.4Sr0.6Co0.4Mn0.6O3 as catalyst shows good cycling stability up to 46 cycles. The good electrochemical performance suggests that suitable doping of Co in Mn site of La0.4Sr0.6MnO3 could be a promising route to improve the catalytic activity.

Nutrition Status Of Children (1-6 Years In Slums Of Ghaziabad City

Directory of Open Access Journals (Sweden)

Garg S.K

1997-01-01

Full Text Available Research question : What are the nutritional problems of pre- school children in slums? Objectives: (i To assess the nutritional status of the children . (ii To find out the nutritional deficiency disorders in them (iii To study their dietary intake. Study design: Cross- sectional. Setting : Slums of Ghaziabad city. Participants :771 children (1-6 years. Study Variables : Age, sex, caste, ICDS beneficiary status, weight, nutritional deficiency disorders, dietary intake and supplementary nutrition. Statistical analysis : Simple proportions and Chi- square test. Results : A majority (58.2 % of children were having under nutrition of varying grades irrespective of their sex and caste but influenced by their age and ICDS beneficiary status. Anaemia, xerophthalmia and goitre were present in 14.7%, 1.6% and 0.6 % children respectively. Average daily dietary intake of energy & nutrients were lower than the recommended daily allowances (RDA. Conclusion: Regular nutritional supplementation along with adequate nutrition education would reduce the nutritional deficiency disorders among children.

Mild Cognitive Impairment Status and Mobility Performance

DEFF Research Database (Denmark)

Pedersen, Mette; Holt, Nicole E; Grande, Laura

2014-01-01

: An analysis was conducted on baseline data from the Boston Rehabilitative Impairment Study in the Elderly study, a cohort study of 430 primary care patients aged 65 or older. Neuropsychological tests identified participants with MCI and further subclassified those with impairment in memory domains (a......BACKGROUND: The prevalence of mild cognitive impairment (MCI) and mobility limitations is high among older adults. The aim of this study was to investigate the association between MCI status and both performance-based and self-report measures of mobility in community-dwelling older adults. METHODS...

Periodontal status during pregnancy and postpartum.

Science.gov (United States)

González-Jaranay, Maximino; Téllez, Luís; Roa-López, Antonio; Gómez-Moreno, Gerardo; Moreu, Gerardo

2017-01-01

Different studies have documented an association between periodontal disease and low birth-weight delivery. Hence, knowledge of periodontal status during pregnancy and postpartum is important in order to reduce the risks of both diseases. This study aimed to analyze periodontal status at successive stages of pregnancy and 3-6 weeks postpartum in women with initial periodontal alterations. Ninety-six pregnant women were examined at 8-10 weeks (pregnancy diagnosis, baseline), 21-23 weeks and 34-36 weeks of gestation and at 40 days postpartum to record plaque scores, clinically assessed gingival inflammation and probing depth (mean depth and % sites with depth >3 mm). Bivariate and multivariate analyses were performed. Type 1 (α) error was established at 0.05. Plaque Index increased (p = 0.043) throughout pregnancy (baseline, 42%±0.18); 21-23 weeks, 42.6%±0.14; 34-36 weeks, 45.6%±0.13 and decreased postpartum (44.8%±0-13). Gingival Index increased (ppregnancy (baseline, 56.7%±0.20; 21-23 weeks, 66.36%±0.17; 34-36 weeks, 74.5%±0.18) and decreased postpartum (59.3%±0.21). Probing Depth increased (ppregnancy (baseline, 2.51±0.05; 21-23 weeks, 2.63±0.053; 34-36 weeks 2.81±0.055) and decreased postpartum (2.54±0.049). Percentage of sites with Probing Depth >3 mm increased (ppregnancy (baseline, 17.6%±0.16; 21-23 weeks, 23.9%±0.17; 34-36 weeks, 31.1%±0.17) and decreased postpartum (21.2%±0.17) but remained significantly (pPeriodontal status deteriorates during gestation but improves postpartum.

Far infrared near normal specular reflectivity of Nix(SiO2)1-x (x = 1.0, 0.84, 0.75, 0.61, 0.54, 0.28) granular films

KAUST Repository

Massa, Né stor E.; Denardin, Juliano C.; Socolovsky, Leandro M.; Knobel, Marcelo; De La Cruz, Fernando Pablo; Zhang, Xixiang

2010-01-01

of transition metal granular films with different metal fractions against what is known for conducting oxides. Films for Nix(SiO2)1-x (x = 1.0, 0.84, 0.75, 0.61, 0.54, 0.28) were studied by temperature dependent far infrared measurements. While for pure Ni

Magnetic-entropy change in Mn1.1Fe0.9P0.7As0.3-xGe x

International Nuclear Information System (INIS)

Tegus, O.; Fuquan, B.; Dagula, W.; Zhang, L.; Brueck, E.; Si, P.Z.; Boer, F.R. de; Buschow, K.H.J.

2005-01-01

We have studied the magnetic properties and magnetic-entropy changes of Mn 1.1 Fe 0.9 P 0.7 As 0.3-x Ge x compounds with x = 0, 0.05, 0.1, 0.15 and 0.3. X-ray diffraction (XRD) study shows all the compounds crystallize in the Fe 2 P-type structure. Magnetic measurements show that the Curie temperature increases from 150 K for Mn 1.1 Fe 0.9 P 0.7 As 0.3 to 380 K for Mn 1.1 Fe 0.9 P 0.7 Ge 0.3 . A field-induced first-order magnetic phase transition is observed above the Curie temperature for the compounds with x up to 0.15. There exists an optimal composition in which the first-order phase transition is the sharpest. The optimal composition for this system is x = 0.1. The maximal magnetic-entropy change derived from the magnetization data is about 40 J/(kg K) for a field change from 0 to 3 T

Effect of anode firing on the performance of lanthanum and nickel co-doped SrTiO3 (La0.2Sr0.8Ti0.9Ni0.1O3-δ) anode of solid oxide fuel cell

Science.gov (United States)

Park, Byung Hyun; Choi, Gyeong Man

2015-10-01

Perovskite oxides have potential for use as alternative anode materials in solid oxide fuel cells (SOFCs) due to stability in anode atmosphere; donor-doped SrTiO3 (e.g., La0.2Sr0.8TiO3-δ) is a good candidate for this purpose. Electro-catalytic nanoparticles can be produced in oxide anodes by the ex-solution method, e.g., by incorporating Ni into a perovskite oxide in air, then reducing the oxide in H2 atmosphere. In this study, we varied the temperature (1100, 1250 °C) and atmosphere (air, H2) of La0.2Sr0.8Ti0.9Ni0.1O3-δ (LSTN) anode firing to control the degree of Ni ex-solution and microstructure. LSTN fired at 1250 °C in H2 showed the best anodic performance for scandia-stabilized zirconia (ScSZ) electrolyte-supported cells in H2 and CH4 fuels due to the favorable microstructure and Ni ex-solution.

Effect of Cr-sources on performance of Li1.05Cr0.04Mn1.96O4 cathode materials prepared by slurry spray drying method

International Nuclear Information System (INIS)

Peng, Z.D.; Jiang, Q.L.; Du, K.; Wang, W.G.; Hu, G.R.; Liu, Y.X.

2010-01-01

The effect of Cr-sources on the performance of Li 1.05 Cr 0.04 Mn 1.96 O 4 prepared by slurry spray drying method was studied by adopting three different chromic compounds, Cr 2 O 3 , Cr 2 (SO 4 ) 3 and Cr(CH 3 COO) 3 , respectively. The prepared powder materials were characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), scanning electron microscopy (SEM), laser particle size analyzer and Brunauer-Emmett-Teller (BET) specific surface area test. Electrochemical performances of these cathode materials were investigated by electrochemical impedance spectroscopy (EIS) and charge-discharge tests with Li/LiCr x Mn 2-x O 4 coin-type batteries. The results indicate that porous spherical particles with average particle size of about 24 μm can be obtained by slurry spray drying process. Using Cr(CH 3 COO) 3 as Cr-source resulted in the better mixing properties, which can make the as-prepared CA-Li 1.05 Cr 0.04 Mn 1.96 O 4 having smaller lattice parameter, smaller grain size and better structure stability, and consequently the obtained sample showed low charge transfer impedance and electrochemical polarization, and exhibited good electrochemical performance at elevated temperature.

Self-reported balance status is not a reliable indicator of balance performance in adolescents at one-month post-concussion.

Science.gov (United States)

Rochefort, Coralie; Walters-Stewart, Coren; Aglipay, Mary; Barrowman, Nick; Zemek, Roger; Sveistrup, Heidi

2017-11-01

To determine if self-reported balance symptoms can be used as a proxy for measures of the center of pressure (COP) to identify balance deficits in a group of concussed adolescents. Case-control. Thirteen adolescents 1-month post-concussion who reported ongoing balance problems (Balance+), 20 adolescent 1-month post-concussion who reported no balance problems (Balance-), and 30 non-injured adolescents (control) completed a series of balance tests. Participants completed two 2-min trials standing on a Nintendo Wii Balance Board™ during which the COP under their feet was recorded: i) double-leg stance, eyes open; ii) double-leg stance, eyes closed. Participants also completed a dual-task condition combining a double-leg stance and a Stroop Colour-word test. Participants in both the Balance+ and Balance- group swayed over a larger ellipse area compared to the control group while completing the Eyes Closed (Balance+, p=0.002; Balance-, p=0.002) and Dual-Task (Balance+, p=0.001; Balance-, p=0.004) conditions and performed the Dual-Task condition with faster medio-lateral velocity (Balance+, p=0.003; Balance-, p=0.009). The participants in the Balance- group also swayed over a larger ellipse area compared to the control group while completing the Eyes Open condition (p=0.005). No significant differences were identified between the Balance+ and Balance- groups. At 1-month post-concussion, adolescents demonstrated balance deficits compared to non-injured adolescents regardless of whether they reported balance problems. These results suggest that self-reported balance status might not be an accurate reflection of balance performance following a concussion in adolescents. Copyright © 2017 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

Undernutrition, fatty acid and micronutrient status in relation to cognitive performance in Indian school children: a cross-sectional study.

Science.gov (United States)

Eilander, Ans; Muthayya, Sumithra; van der Knaap, Henk; Srinivasan, Krishnamachari; Thomas, Tinku; Kok, Frans J; Kurpad, Anura V; Osendarp, Saskia J M

2010-04-01

While undernutrition and anaemia have previously been linked to poor development of children, relatively little is known about the role of B-vitamins and fatty acids on cognition. The present study aims to explore the associations between indicators of body size, fatty acid and micronutrient status on cognitive performance in 598 Indian school children aged 6-10 years. Baseline data of a clinical study were used to assess these associations by analyses of variance adjusting for age, sex, school, maternal education and cognitive tester. The Kaufman Assessment Battery for Children II was used to measure four cognitive domains, including fluid reasoning, short-term memory, retrieval ability and cognitive speediness. Scores were combined into an overall measure, named mental processing index (MPI). Body size indicators and Hb concentrations were significantly positively related to cognitive domains and MPI, such that increases of 1 sd in height-for-age and weight-for-age z-scores would each translate into a 0.09 sd increase in MPI, P = 0.0006 and 0.002, respectively. A 10 g/l increase in Hb concentrations would translate into a 0.08 sd increase in MPI, P = 0.0008. Log-transformed vitamin B12 concentrations were significantly inversely associated with short-term memory, retrieval ability and MPI (beta (95 % CI) = - 0.124 (- 0.224, - 0.023), P = 0.02). Other indicators of Fe, iodine, folate and fatty acid status were not significantly related to cognition. Our findings for body size, fatty acids and micronutrients were in agreement with previous observational studies. The inverse association of vitamin B12 with mental development was unexpected and needed further study.

Epigenetics in type 1 diabetes: TNFa gene promoter methylation status in Chilean patients with type 1 diabetes mellitus.

Science.gov (United States)

Arroyo-Jousse, Viviana; Garcia-Diaz, Diego F; Codner, Ethel; Pérez-Bravo, Francisco

2016-12-01

TNF-α is a pro-inflammatory cytokine that is involved in type 1 diabetes (T1D) pathogenesis. The TNFa gene is subject of epigenetic regulation in which folate and homocysteine are important molecules because they participate in the methionine cycle where the most important methyl group donor (S-adenosylmethionine) is formed. We investigated whether TNFa gene promoter methylation status in T1D patients was related to blood folate, homocysteine and TNF-α in a transversal case-control study. We studied T1D patients (n 25, mean=13·7 years) and healthy control subjects (n 25, mean=31·1 years), without T1D and/or other autoimmune diseases or direct family history of these diseases. A blood sample was obtained for determination of serum folate, plasma homocysteine and TNF-α concentrations. Whole blood was used for the extraction of DNA to determine the percentage of methylation by real-time PCR and melting-curve analysis. Results are expressed as means and standard deviations for parametric variables and as median (interquartile range) for non-parametric variables. T1D patients showed a higher TNFa gene promoter methylation (39·2 (sd 19·5) %) when compared with control subjects (25·4 (sd 13·7) %) (P=0·008). TNFa gene promoter methylation was positively associated only with homocysteine levels in T1D patients (r 0·55, P=0·007), but not in control subjects (r -0·122, P=0·872). To our knowledge, this is the first work that reports the methylation status of the TNFa gene promoter and its relationship with homocysteine metabolism in Chilean T1D patients without disease complications.

Risk of seizures and status epilepticus in older patients with liver disease.

Science.gov (United States)

Alkhachroum, Ayham M; Rubinos, Clio; Kummer, Benjamin R; Parikh, Neal S; Chen, Monica; Chatterjee, Abhinaba; Reynolds, Alexandra; Merkler, Alexander E; Claassen, Jan; Kamel, Hooman

2018-06-06

Seizures can be provoked by systemic diseases associated with metabolic derangements, but the association between liver disease and seizures remains unclear. We performed a retrospective cohort study using inpatient and outpatient claims between 2008 and 2015 from a nationally representative 5% sample of Medicare beneficiaries. The primary exposure variable was cirrhosis, and the secondary exposure was mild, noncirrhotic liver disease. The primary outcome was seizure, and the secondary outcome was status epilepticus. Diagnoses were ascertained using validated International Classification of Diseases, Ninth Edition, Clinical Modification codes. Survival statistics were used to calculate incidence rates, and Cox proportional hazards models were used to examine the association between exposures and outcomes while adjusting for seizure risk factors. Among 1 782 402 beneficiaries, we identified 10 393 (0.6%) beneficiaries with cirrhosis and 19 557 (1.1%) with mild, noncirrhotic liver disease. Individuals with liver disease were older and had more seizure risk factors than those without liver disease. Over 4.6 ± 2.2 years of follow-up, 49 843 (2.8%) individuals were diagnosed with seizures and 25 patients (0.001%) were diagnosed with status epilepticus. Cirrhosis was not associated with seizures (hazard ratio [HR] = 1.1, 95% confidence interval [CI] = 1.0-1.3), but there was an association with status epilepticus (HR = 1.9, 95% CI = 1.3-2.8). Mild liver disease was not associated with a higher risk of seizures (HR = 0.8, 95% CI = 0.6-0.9) or status epilepticus (HR = 1.1, 95% CI = 0.7-1.5). In a large, population-based cohort, we found an association between cirrhosis and status epilepticus, but no overall association between liver disease and seizures. Wiley Periodicals, Inc. © 2018 International League Against Epilepsy.

Cohabitation and marital status as predictors of mortality--an eight year follow-up study

DEFF Research Database (Denmark)

Lund, Rikke; Due, Pernille; Modvig, Jens

2002-01-01

.25(0.93-1.69), adjusted for the same covariates. Inclusion of the health behaviour variables--smoking, diet and physical activity--one by one to a model with functional ability, self-rated health and one of the three determinants (cohabitation status, living with/without partner, marital status) showed no effect...... compared to individuals living with somebody HR = 1.42(1.04-1.95) adjusted for functional ability, self-rated health, having children, smoking, diet and physical activity. Similar analyses were performed for the variable living with/without a partner HR = 1.38(1.01-1.88) and marital status HR = 1...

GAMBARAN STATUS NUTRISI, POLA KONSUMSI SARAPAN DAN CEMILAN PADA SISWA SEKOLAH DASAR NEGERI 1 GIANYAR

Directory of Open Access Journals (Sweden)

Mirah Sucita Dewi

2015-08-01

Full Text Available ABSTRACT Breakfast has been known as the most important meal, and it is often missed by children of primary school age and adolescence. Children who eat breakfast regularly have better nutritional profile compared to children who do not eat breakfast. Consumption midmorning snack before lunch is also known in increasing body mass index (BMI.This study is a descriptive cross-sectional approach. Research sample are 5th grade students of SD Negeri 1 Gianyar, located in Puskesmas Gianyar I work area. Total sample was 85 children. Purposive sampling was used as sampling technique by selecting the entire 5th grade students of SD Negeri 1 Gianyar. Data was obtained by questionnaires to the students that were selected as respondents. Data analysis was performed as univariate and bivariate. Study found that almost all (91.80% samples implemented breakfast behavior, and the rest (8.20% did not have breakfast. Samples that implemented the behavior of the breakfast, mostly of them had undernutrition status (56.4 %, followed by normal nutritional status (26.9 % and overnutrition status (16.7%. At samples that eat snacks, most of them had undernutrition status (58.2%, followed by normal nutritional status (26.6 % and overnutrition status (15.2%.Most of the students of SD Negeri 1 Gianyar had breakfast. Group of students who skipped breakfast and/or skipped snack has higher percentage of normal nutritional status. Keywords: breakfast, snacks, Nutritional Status, Elementary school students

Relationship between the degree of insulin resistance during late gestation and postpartum performance in dairy cows and factors that affect growth and metabolic status of their calves.

Science.gov (United States)

Kawashima, Chiho; Munakata, Megumi; Shimizu, Takashi; Miyamoto, Akio; Kida, Katsuya; Matsui, Motozumi

2016-06-01

This study aimed to investigate the effects of insulin resistance (IR) during the close-up dry period on the metabolic status and performance of dairy cows as well as to determine the effects on body weight (BW) and metabolic status of their calves. An insulin tolerance test (ITT) was conducted by administering 0.05 IU/kg BW of insulin to 34 multiparous Holstein cows at 3 weeks prepartum. Blood samples were collected at 0, 30, 45 and 60 min after insulin injection, and cows were divided into two groups based on the time required for glucose to reach the minimum levels [non-IR (NIR), 45 min (n=28); and IR, 60 min (n=6)]. Blood or milk sampling and body condition score (BCS) estimation were performed twice weekly during the experimental period. Blood samples from calves were collected immediately after birth. Cows with IR showed lower BCS (Pinsulin-like growth factor-I concentration (Pinsulin concentration (Pdairy cows is related to postpartum metabolic status and performance along with growth and metabolic status of their calves.

Status Report on Scoping Reactor Physics and Sensitivity/Uncertainty Analysis of LR-0 Reactor Molten Salt Experiments

Energy Technology Data Exchange (ETDEWEB)

Brown, Nicholas R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Reactor and Nuclear Systems Division; Mueller, Donald E. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Reactor and Nuclear Systems Division; Patton, Bruce W. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Reactor and Nuclear Systems Division; Powers, Jeffrey J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Reactor and Nuclear Systems Division

2016-08-31

Experiments are being planned at Research Centre Rež (RC Rež) to use the FLiBe (2 ⁷LiF-BeF₂) salt from the Molten Salt Reactor Experiment (MSRE) to perform reactor physics measurements in the LR-0 low power nuclear reactor. These experiments are intended to inform on neutron spectral effects and nuclear data uncertainties for advanced reactor systems utilizing FLiBe salt in a thermal neutron energy spectrum. Oak Ridge National Laboratory (ORNL) is performing sensitivity/uncertainty (S/U) analysis of these planned experiments as part of the ongoing collaboration between the United States and the Czech Republic on civilian nuclear energy research and development. The objective of these analyses is to produce the sensitivity of neutron multiplication to cross section data on an energy-dependent basis for specific nuclides. This report provides a status update on the S/U analyses of critical experiments at the LR-0 Reactor relevant to fluoride salt-cooled high temperature reactor (FHR) and liquid-fueled molten salt reactor (MSR) concepts. The S/U analyses will be used to inform design of FLiBe-based experiments using the salt from MSRE.

Status Report on Scoping Reactor Physics and Sensitivity/Uncertainty Analysis of LR-0 Reactor Molten Salt Experiments

International Nuclear Information System (INIS)

Brown, Nicholas R.; Mueller, Donald E.; Patton, Bruce W.; Powers, Jeffrey J.

2016-01-01

Experiments are being planned at Research Centre Rež (RC Rež) to use the FLiBe (2 "7LiF-BeF_2) salt from the Molten Salt Reactor Experiment (MSRE) to perform reactor physics measurements in the LR-0 low power nuclear reactor. These experiments are intended to inform on neutron spectral effects and nuclear data uncertainties for advanced reactor systems utilizing FLiBe salt in a thermal neutron energy spectrum. Oak Ridge National Laboratory (ORNL) is performing sensitivity/uncertainty (S/U) analysis of these planned experiments as part of the ongoing collaboration between the United States and the Czech Republic on civilian nuclear energy research and development. The objective of these analyses is to produce the sensitivity of neutron multiplication to cross section data on an energy-dependent basis for specific nuclides. This report provides a status update on the S/U analyses of critical experiments at the LR-0 Reactor relevant to fluoride salt-cooled high temperature reactor (FHR) and liquid-fueled molten salt reactor (MSR) concepts. The S/U analyses will be used to inform design of FLiBe-based experiments using the salt from MSRE.

Observation of B{sub s}{sup 0}→χ{sub c1}ϕ decay and study of B{sup 0}→χ{sub c1,2}K{sup ⁎0} decays

Energy Technology Data Exchange (ETDEWEB)

Aaij, R. [Nikhef National Institute for Subatomic Physics, Amsterdam (Netherlands); Adeva, B. [Universidad de Santiago de Compostela, Santiago de Compostela (Spain); Adinolfi, M. [H.H. Wills Physics Laboratory, University of Bristol, Bristol (United Kingdom); Adrover, C. [CPPM, Aix-Marseille Université, CNRS/IN2P3, Marseille (France); Affolder, A. [Oliver Lodge Laboratory, University of Liverpool, Liverpool (United Kingdom); Ajaltouni, Z. [Clermont Université, Université Blaise Pascal, CNRS/IN2P3, LPC, Clermont-Ferrand (France); Albrecht, J. [Fakultät Physik, Technische Universität Dortmund, Dortmund (Germany); Alessio, F. [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Alexander, M. [School of Physics and Astronomy, University of Glasgow, Glasgow (United Kingdom); Ali, S. [Nikhef National Institute for Subatomic Physics, Amsterdam (Netherlands); Alkhazov, G. [Petersburg Nuclear Physics Institute (PNPI), Gatchina (Russian Federation); Alvarez Cartelle, P. [Universidad de Santiago de Compostela, Santiago de Compostela (Spain); Alves, A.A. [Sezione INFN di Roma La Sapienza, Roma (Italy); European Organization for Nuclear Research (CERN), Geneva (Switzerland); Amato, S. [Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro (Brazil); Amerio, S. [Sezione INFN di Padova, Padova (Italy); Amhis, Y. [LAL, Université Paris-Sud, CNRS/IN2P3, Orsay (France); Anderlini, L. [Sezione INFN di Firenze, Firenze (Italy); Anderson, J. [Physik-Institut, Universität Zürich, Zürich (Switzerland); Andreassen, R. [University of Cincinnati, Cincinnati, OH (United States); Andrews, J.E. [University of Maryland, College Park, MD (United States); and others

2013-09-21

The first observation of the decay B{sub s}{sup 0}→χ{sub c1}ϕ and a study of B{sup 0}→χ{sub c1,2}K{sup ⁎0} decays are presented. The analysis is performed using a dataset, corresponding to an integrated luminosity of 1.0 fb{sup −1}, collected by the LHCb experiment in pp collisions at a centre-of-mass energy of 7 TeV. The following ratios of branching fractions are measured: (table) where the third uncertainty is due to the limited knowledge of the branching fractions of χ{sub c}→J/ψγ modes.

Novel solid oxide cells with SrCo0.8Fe0.1Ga0.1O3-δ oxygen electrode for flexible power generation and hydrogen production

Science.gov (United States)

Meng, Xiuxia; Shen, Yichi; Xie, Menghan; Yin, Yimei; Yang, Naitao; Ma, Zi-Feng; Diniz da Costa, João C.; Liu, Shaomin

2016-02-01

This work investigates the performance of solid oxide cells as fuel cells (SOFCs) for power production and also as electrolysis cells (SOECs) for hydrogen production. In order to deliver this dual mode flexible operation system, a novel perovskite oxide based on Ga3+ doped SrCo0.8Fe0.1Ga0.1O3-δ (SCFG) is synthesized via a sol-gel method. Its performance for oxygen electrode catalyst was then evaluated. Single solid oxide cell in the configuration of Ni-YSZ|YSZ|GDC|SCFG is assembled and tested in SOFC or SOEC modes from 550 to 850 °C with hydrogen as the fuel or as the product, respectively. GDC is used to avoid the reaction between the electrolyte YSZ and the cobalt-based electrode. Under SOFC mode, a maximum power density of 1044 mW cm-2 is obtained at 750 °C. Further, the cell delivers a stable power output of 650 mW cm-2 up to 125 h at 0.7 V. In the electrolysis mode, when the applied voltage is controlled at 2 V, the electrolysis current density reaches 3.33 A cm-2 at 850 °C with the hydrogen production rate up to 22.9 mL min-1 cm-2 (STP). These results reveal that SCFG is a very promising oxygen electrode material for application in both SOFC and SOEC.

Routine clinical knee MR reports: comparison of diagnostic performance at 1.5 T and 3.0 T for assessment of the articular cartilage.

Science.gov (United States)

Mandell, Jacob C; Rhodes, Jeffrey A; Shah, Nehal; Gaviola, Glenn C; Gomoll, Andreas H; Smith, Stacy E

2017-11-01

Accurate assessment of knee articular cartilage is clinically important. Although 3.0 Tesla (T) MRI is reported to offer improved diagnostic performance, literature regarding the clinical impact of MRI field strength is lacking. The purpose of this study is to compare the diagnostic performance of clinical MRI reports for assessment of cartilage at 1.5 and 3.0 T in comparison to arthroscopy. This IRB-approved retrospective study consisted of 300 consecutive knees in 297 patients who had routine clinical MRI and arthroscopy. Descriptions of cartilage from MRI reports of 165 knees at 1.5 T and 135 at 3.0 T were compared with arthroscopy. The sensitivity, specificity, percent of articular surfaces graded concordantly, and percent of articular surfaces graded within one grade of the arthroscopic grading were calculated for each articular surface at 1.5 and 3.0 T. Agreement between MRI and arthroscopy was calculated with the weighted-kappa statistic. Significance testing was performed utilizing the z-test after bootstrapping to obtain the standard error. The sensitivity, specificity, percent of articular surfaces graded concordantly, and percent of articular surfaces graded within one grade were 61.4%, 82.7%, 62.2%, and 77.5% at 1.5 T and 61.8%, 80.6%, 59.5%, and 75.6% at 3.0 T, respectively. The weighted kappa statistic was 0.56 at 1.5 T and 0.55 at 3.0 T. There was no statistically significant difference in any of these parameters between 1.5 and 3.0 T. Factors potentially contributing to the lack of diagnostic advantage of 3.0 T MRI are discussed.

Performance comparison of machine learning methods for prognosis of hormone receptor status in breast cancer tissue samples.

Science.gov (United States)

Kalinli, Adem; Sarikoc, Fatih; Akgun, Hulya; Ozturk, Figen

2013-06-01

We examined the classification and prognostic scoring performances of several computer methods on different feature sets to obtain objective and reproducible analysis of estrogen receptor status in breast cancer tissue samples. Radial basis function network, k-nearest neighborhood search, support vector machines, naive bayes, functional trees, and k-means clustering algorithm were applied to the test datasets. Several features were employed and the classification accuracies of each method for these features were examined. The assessment results of the methods on test images were also experimentally compared with those of two experts. According to the results of our experimental work, a combination of functional trees and the naive bayes classifier gave the best prognostic scores indicating very good kappa agreement values (κ=0.899 and κ=0.949, p<0.001) with the experts. This combination also gave the best dichotomization rate (96.3%) for assessment of estrogen receptor status. Wavelet color features provided better classification accuracy than Laws texture energy and co-occurrence matrix features. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Single-crystal LiNi{sub 0.6}Co{sub 0.2}Mn{sub 0.2}O{sub 2} as high performance cathode materials for Li-ion batteries

Energy Technology Data Exchange (ETDEWEB)

Wang, Lei [School of Materials Science and Engineering, Beijing Institute of Technology, Beijing Key Laboratory of Environment Science and Engineering, Beijing 100081 (China); Wu, Borong, E-mail: wubr@bit.edu.cn [School of Materials Science and Engineering, Beijing Institute of Technology, Beijing Key Laboratory of Environment Science and Engineering, Beijing 100081 (China); Beijing Higher Institution Engineering Research Center of Power Battery and Chemical Energy Materials, Beijing 100081 (China); Collaborative Innovation Center of Electric Vehicles in Beijing, Beijing 100081 (China); Mu, Daobin, E-mail: mudb@bit.edu.cn [School of Materials Science and Engineering, Beijing Institute of Technology, Beijing Key Laboratory of Environment Science and Engineering, Beijing 100081 (China); Beijing Higher Institution Engineering Research Center of Power Battery and Chemical Energy Materials, Beijing 100081 (China); Liu, Xiaojiang [Institute of Electric Engineering, China Academy of Engineering Physics, Mianyang 621900 (China); Peng, Yiyuan [Key Laboratory of Small Fuctional Organic Molecule, Ministry of Education, Jiangxi Normal University, Nanchang 330022 (China); Xu, Hongliang; Liu, Qi; Gai, Liang [School of Materials Science and Engineering, Beijing Institute of Technology, Beijing Key Laboratory of Environment Science and Engineering, Beijing 100081 (China); Wu, Feng [School of Materials Science and Engineering, Beijing Institute of Technology, Beijing Key Laboratory of Environment Science and Engineering, Beijing 100081 (China); Beijing Higher Institution Engineering Research Center of Power Battery and Chemical Energy Materials, Beijing 100081 (China); Collaborative Innovation Center of Electric Vehicles in Beijing, Beijing 100081 (China)

2016-07-25

Single-crystal nickel-high materials (ST-LNCMO) LiNi{sub 0.6}Co{sub 0.2}Mn{sub 0.2}O{sub 2} have been synthesized using a versatile hydrothermal method. The as-prepared samples are characterized by X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), transmission electron microscope (TEM), and selected area electron diffraction (SAED). The results show that the sample annealed at an optimized temperature of 850 °C reveals uniform fine well-crystallized single-particles with diameters of ~800 nm. Electrochemical data demonstrate that the cell using this nickel-high material as the cathode exhibits excellent performance. The sample displays a high capacity of 183.7 mA h·g{sup −1} at 36 mA·g{sup −1} (0.2 C) and excellent cycling stability at different rates. It yields an initial discharge capacity of 153.6 mA h·g{sup −1} at a rate of 10C-rate and a voltage of 2.8 V – 4.3 V. The sample also has an outstanding rate capacity at a high cut-off voltage (4.6 V). This superior performance is attributed to the merits of the single-crystal structure, which may be beneficial to the transportation of the Li{sup +} ion along the grain. - Highlights: • A single-crystal LiNi{sub 0.6}Co{sub 0.2}Mn{sub 0.2}O{sub 2} is prepared by a hydrothermal method. • A high discharge capacity of 183.7 mA h·g{sup −1} at 0.2 C and good cycling stability. • It yields an initial discharge capacity of 153.6 mA h·g{sup −1} at 10 C-rate under 2.8 V–4.3 V. • Superior electrochemical performance may be obtained attributed to the single-crystal structure.

Electrochemical Activity of a La0.9Ca0.1Co1−xFexO3 Catalyst for a Zinc Air Battery Electrode

Directory of Open Access Journals (Sweden)

Seungwook Eom

2015-01-01

Full Text Available The optimum composition of cathode catalyst has been studied for rechargeable zinc air battery application. La0.9Ca0.1Co1−xFexO3  (x=0–0.4 perovskite powders were prepared using the citrate method. The substitution ratio of Co2+ with Fe3+ cations was controlled in the range of 0–0.4. The optimum substitution ratio of Fe3+ cations was determined by electrochemical measurement of the air cathode composed of the catalyst, polytetrafluoroethylene (PTFE binder, and Vulcan XC-72 carbon. The substitution by Fe enhanced the electrochemical performances of the catalysts. Considering oxygen reduction/evolution reactions and cyclability, we achieved optimum substitution level of x=0.1 in La0.9Ca0.1Co1−xFexO3.

Progressive decline of decision-making performances during multiple sclerosis.

Science.gov (United States)

Simioni, Samanta; Ruffieux, Christiane; Kleeberg, Joerg; Bruggimann, Laure; du Pasquier, Renaud A; Annoni, Jean-Marie; Schluep, Myriam

2009-03-01

The purpose of this study was to evaluate longitudinally, using the Iowa Gambling Task (IGT), the dynamics of decision-making capacity at a two-year interval (median: 2.1 years) in a group of patients with multiple sclerosis (MS) (n = 70) and minor neurological disability [Expanded Disability Status Scale (EDSS) attention), behavior, handicap, and perceived health status were also investigated. Standardized change scores [(score at retest-score at baseline)/standard deviation of baseline score] were computed. Results showed that IGT performances decreased from baseline to retest (from 0.3, SD = 0.4 to 0.1, SD = 0.3, p = .005). MS patients who worsened in the IGT were more likely to show a decreased perceived health status and emotional well-being (SEP-59; p = .05 for both). Relapsing rate, disability progression, cognitive, and behavioral changes were not associated with decreased IGT performances. In conclusion, decline in decision making can appear as an isolated deficit in MS.

Thermoelectric properties of p-type pseudo-binary (Ag0.365Sb0.558Te) x -(Bi0.5Sb1.5Te3)1-x (x=0-1.0) alloys prepared by spark plasma sintering

International Nuclear Information System (INIS)

Cui, J.L.; Xue, H.F.; Xiu, W.J.; Jiang, L.; Ying, P.Z.

2006-01-01

In this paper, pseudo-binary (Ag 0.365 Sb 0.558 Te) x -(Bi 0.5 Sb 1.5 Te 3 ) 1- x (x=0-1.0) alloys were prepared using spark plasma sintering technique, and the composition-dependent thermoelectric properties were evaluated. Electrical conductivities range from 7.9x10 4 to 15.6x10 4 Ω -1 m -1 at temperatures of 507 and 318 K, respectively, being about 3.0 and 8.5 times those of Bi 0.5 Sb 1.5 Te 3 alloy at the corresponding temperatures. The optimal dimensionless figure of merit (ZT) of the sample with molar fraction x=0.025 reaches 1.1 at 478 K, whereas that of the ternary Bi 0.5 Sb 1.5 Te 3 alloy is 0.58 near room temperature. The results also reveal that a direct introduction of Ag 0.365 Sb 0.558 Te in the Bi-Sb-Te system is much more effective to the property improvement than naturally precipitated Ag 0.365 Sb 0.558 Te in the Ag-doped Ag-Bi-Sb-Te system. - Graphical abstract: The temperature dependence of the dimensionless thermoelectric figure of merit ZT for different (Ag 0.365 Sb 0.558 Te) x -(Bi 0.5 Sb 1.5 Te 3 ) 1- x (x=0-1.0) alloys prepared by spark plasma sintering

Estimates of Job Performance for Applicants Differing in Gender, Marital and Parental Status.

Science.gov (United States)

Borges, Marilyn A.; Clothier, Tamara A.

Women and men tend to be defined by their marital and parental status; thus, these factors may be crucial in understanding societal attitudes toward working men and women. The influence of marital and parental status on perceived job performance was investigated with a college undergraduate sample (N=128). From paragraph descriptions that varied…

Effect of thermal treatment on the characteristics of iridium Schottky barrier diodes on n-Ge (1 0 0)

International Nuclear Information System (INIS)

Chawanda, A.; Coelho, S.M.M.; Auret, F.D.; Mtangi, W.; Nyamhere, C.; Nel, J.M.; Diale, M.

2012-01-01

Highlights: ► Ir/n-Ge (1 0 0) Schottky diodes were characterized using I–V, C–V and SEM techniques under various annealing conditions. ► The variation of the electrical and structural properties can be due to effects phase transformation during annealing. ► Thermal stability of these diodes is maintained up to 500 °C anneal. ► SEM results depicts that the onset temperature for agglomeration in 20 nm Ir/n-Ge (1 0 0) system occurs between 600 and 700 °C. - Abstract: Iridium (Ir) Schottky barrier diodes were deposited on bulk grown (1 0 0) Sb-doped n-type germanium by using the electron beam deposition system. Electrical characterization of these contacts using current–voltage (I–V) and capacitance–voltage (C–V) measurements was performed under various annealing conditions. The variation of the electrical properties of these Schottky diodes can be attributed to combined effects of interfacial reaction and phase transformation during the annealing process. Thermal stability of the Ir/n-Ge (1 0 0) was observed up to annealing temperature of 500 °C. Furthermore, structural characterization of these samples was performed by using a scanning electron microscopy (SEM) at different annealing temperatures. Results have also revealed that the onset temperature for agglomeration in a 20 nm Ir/n-Ge (1 0 0) system occurs between 600 and 700 °C.

Status report of K{sub s}{sup 0} multiplicities from 2006 at COMPASS

Energy Technology Data Exchange (ETDEWEB)

Hahne, Daniel [Universitaet Bonn (Germany)

2014-07-01

To describe the hadronization process of quarks into hadrons in deep inelastic scattering knowledge of parton distribution functions and fragmentation functions is necessary. Parton distribution functions can be extracted from inclusive deep inelastic scattering. To extract fragmentation functions from data taken by the COMPASS experiment final state hadrons are analyzed in addition to the incoming and scattered muon. I give a status report of K{sub s}{sup 0} multiplicities from data taken in 2006 by the COMPASS experiment which can be used to parameterize K{sub s}{sup 0} fragmentation functions.

Effect of 12-Week Vitamin D Supplementation on 25[OH]D Status and Performance in Athletes with a Spinal Cord Injury

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Joelle Leonie Flueck

2016-09-01

Full Text Available (1 Background: studies with able-bodied athletes showed that performance might possibly be influenced by vitamin D status. Vitamin D seems to have a direct impact on neuromuscular function by docking on vitamin D receptors in the muscle tissue. Additionally, a high prevalence of vitamin D deficiency was shown not only in infants and in the elderly but also in healthy adults and spinal cord injured individuals. Therefore, the aim of our study was to investigate whether a vitamin D dose of 6000 IU daily over 12 weeks would be sufficient to increase vitamin D status in indoor wheelchair athletes to a normal or optimal vitamin D level and whether vitamin D deficiency is associated with an impairment in muscle performance in these individuals; (2 Methods: vitamin D status was assessed in indoor elite wheelchair athletes in order to have a baseline measurement. If vitamin D status was below 75 nmol/L, athletes were supplemented with 6000 IU of vitamin D daily over 12 weeks. A vitamin D status over 75 nmol/L was supplemented with a placebo supplement. Vitamin D status, as well as a Wingate test and an isokinetic dynamometer test, were performed at baseline and after six and 12 weeks; (3 Results: 20 indoor elite wheelchair athletes participated in this double-blind study. All of these athletes showed an insufficient vitamin D status at baseline and were, therefore, supplemented with vitamin D. All athletes increased vitamin D status significantly over 12 weeks and reached an optimal level. Wingate performance was not significantly increased. Isokinetic dynamometer strength was significantly increased but only in the non-dominant arm in isometric and concentric elbow flexion; (4 Conclusion: a dose of 6000 IU of vitamin D daily over a duration of 12 weeks seems to be sufficient to increase vitamin D status to an optimal level in indoor wheelchair athletes. It remains unclear, whether upper body performance or muscle strength and vitamin D status are

Metastable and stable magnetic phases in as-cast and annealed Pr80Fe15(B1-xCx)5 alloys (0.0≤x≤1.0)

International Nuclear Information System (INIS)

Sanchez Llamazares, J.L.; Lopez, G.; Fidler, J.

1998-01-01

In as-cast Pr 80 Fe 15 (B 1-x C x ) 5 , samples metastable A 1 (T c =225 C) was the predominant magnetic phase in the whole composition range, with intrinsic properties that were not affected with increasing C content. Up to x=0.75 this phase coexists with an additional minor magnetic phase having T c =263 C which has been labelled by us to as A 3 . Upon annealing at 600 C A 1 dissolves and the following stable phases were observed: (a) Pr 2 Fe 14 B and A 3 for 0.0≤x≤0.75, and; (b) an unknown stable phase D 1 with coercivity around 2.1 kOe and Curie temperature of 230 C for x=1.0. D 1 is the predominant phase for annealing times less than 8 h while for 8 and 16 h annealing an additional phase with T c =17 C appears. The latter has been tentatively identified as Pr 2 Fe 17 . SEM and X-ray microanalysis studies were performed on Pr 80 Fe 15 C 5 samples in the as-cast state and after 16 h of annealing. The as-cast sample shows large Pr-rich grains immersed in a fine eutectic microstructure consisting of Pr and Fe. In annealed samples, both large square or polygonal grains and a needle-like phase are formed. The latter is believed to be D 1 . (orig.)

Magnetic phase diagram of Co(Cr1-xA lx) 2O4 (x = 0.0-1.0)

Science.gov (United States)

Padam, R.; Sarkar, T.; Mathieu, R.; Thota, S.; Pal, D.

2017-08-01

We report the role of Al substitution in the magnetic properties of spinel CoCr2O4 by means of temperature dependent dc and ac magnetization and heat capacity measurements. Various compositions (0.0 ≤ x ≤ 1.0) of polycrystalline Co(Cr1-xAlx)2O4 samples have been prepared by sol-gel processing and their crystal structure was investigated by X-ray diffraction which was found to crystallize in the normal cubic spinel structure. For x ≤ 0.1, the system exhibits multiple magnetic orderings (long range ferrimagnetic ordering TC, spin-spiral ordering TS, and lock-in transition TL), similar to that of the parent compound, CoCr2O4. However, all the compositions between x = 0.1 and 0.5 exhibit long range ferrimagnetic ordering below TC and also a short range order at low temperature. Spin-glass like ordering was noticed between x = 0.6 and 0.8 due to the diluted B-site occupancy, whereas the end compound CoAl2O4 (x = 1.0) shows antiferromagnetic behavior. On the basis of these results, we propose a magnetic phase diagram for the Co(Cr1-xAlx)2O4 series as a function of the Al content (x) and measuring temperature (T).

Impact of the Ki-67 labeling index and p53 expression status on disease-free survival in pT1 urothelial carcinoma of the bladder.

Science.gov (United States)

Vetterlein, Malte W; Roschinski, Julia; Gild, Philipp; Marks, Phillip; Soave, Armin; Doh, Ousman; Isbarn, Hendrik; Höppner, Wolfgang; Wagner, Walter; Shariat, Shahrokh F; Brausi, Maurizio; Büscheck, Franziska; Sauter, Guido; Fisch, Margit; Rink, Michael

2017-12-01

The identification of protein biomarkers to guide treatment decisions regarding adjuvant therapies for high-risk non-muscle-invasive bladder cancer (NMIBC) has been of increasing interest. Evidence of the impact of tumor suppressor gene product p53 and cell proliferation marker Ki-67 on oncologic outcomes in bladder cancer patients at highest risk of recurrence and progression is partially contradictory. We sought to mirror contemporary expression patterns of p53 and Ki-67 in a select cohort of patients with pT1 bladder cancer. Patients from four Northern German institutions with a primary diagnosis of pT1 bladder cancer between 2009 and 2016 and complete data regarding p53 or Ki-67 expression status were included for final analyses. Baseline patient characteristics (age, gender, age-adjusted Charlson comorbidity index) and tumor characteristics [diagnostic sequence, tumor focality, concomitant carcinoma in situ, 1973 World Health Organization (WHO) grading, lymphovascular invasion, adjuvant instillation therapy] were abstracted by retrospective chart review. Immunohistochemistry for detection of p53 and Ki-67 expression was performed according to standardized protocols. Microscopic analyses were performed by central pathologic review. First, we compared patients with positive vs. negative p53 expression and Ki-67 labeling index [>40% vs. ≤40%; cutoffs based on best discriminative ability in univariable Cox regression analysis with disease-free survival (DFS) as endpoint] with regard to baseline and tumor characteristics. Second, we evaluated the effect of biomarker positivity on DFS by plotting univariable Kaplan-Meier curves and performing uni- and multivariable Cox regression analyses. Of 102 patients with complete information on p53 status, 44 (43.1%) were p53 positive, and they more often harbored concomitant carcinoma in situ (50.0% vs. 27.6%; P=0.032) and 1973 WHO grade 3 (97.7% vs. 69.0%; P=0.001) compared to their p53 negative counterparts. Of 79

Effect of chemical treatment on the electrochemical properties of Li1.2NixMn0.8-xO2 (x = 0.2 and 0.25) in lithium-ion batteries

Science.gov (United States)

Konishi, Hiroaki; Hirano, Tatsumi; Takamatsu, Daiko; Gunji, Akira; Feng, Xiaoliang; Furutsuki, Sho; Okumura, Takefumi; Terada, Shohei

2018-02-01

The effect of chemical treatment using (NH4)2SO4 on the electrochemical properties of Li1.2Ni0.2Mn0.6O2 and Li1.2Ni0.25Mn0.55O2 was investigated. The treatment was effective in improving the Coulombic efficiency and discharge capacity of a Li1.2Ni0.2Mn0.6O2 cathode, but treatment with too much (NH4)2SO4 degraded the cathode's electrochemical performance. The effect of (NH4)2SO4 treatment on the charge-discharge reaction mechanism of Li1.2Ni0.2Mn0.6O2 was investigated by evaluating reaction potential, particle configuration, and oxidation state of transition metal. The experimental results indicated that the changes in the electrochemical performance of the treated cathodes were attributed to the changes in the surface state and of the element contributing to the redox reaction. Treatment with an appropriate amount of (NH4)2SO4 also improved the electrochemical performance of the high-nickel-content lithium-rich layer-structured cathode material Li1.2Ni0.25Mn0.55O2.

Synthesis, characterization and mechanoluminescence of europium doped ZnxBa(1−x)Al2O4 (x=0, 0.4, 0.5, 0.6, 0.8, 1.0) phosphor

International Nuclear Information System (INIS)

Sajan, S.J.; Gopakumar, N.; Anjana, P.S.; Madhukumar, K.

2016-01-01

The samples of Zn x Ba (1−x) Al 2 O 4 :0.1%Eu (x=0, 0.4, 0.5, 0.6, 0.8, 1.0) were prepared via high temperature solid state reaction method. The phase formation of the powder samples were confirmed by taking X-ray diffraction analysis. The mechanoluminescence (ML) property of the samples by impact method was studied by using ML measuring apparatus. The variations in the ML peak intensity due to the impact velocity of a load falling from different heights and due to the variation of composition were investigated. The photoluminescence studies of the samples were also conducted.

Performance analysis of spectrum sensing with multiple status changes in primary user traffic

KAUST Repository

Tang, Liang

2012-06-01

In this letter, the impact of primary user traffic with multiple status changes on the spectrum sensing performance is analyzed. Closed-form expressions for the probabilities of false alarm and detection are derived. Numerical results show that the multiple status changes of the primary user cause considerable degradation in the sensing performance. This degradation depends on the number of changes, the primary user traffic model, the primary user traffic intensity and the signal-to-noise ratio of the received signal. Numerical results also show that the amount of degradation decreases when the number of changes increases, and converges to a minimum sensing performance due to the limited sensing period and primary holding time. © 2012 IEEE.

Radiation portal monitor with "1"0B+ZnS(Ag) neutron detector performance for the detection of special nuclear materials

International Nuclear Information System (INIS)

Guzman G, K. A.; Gallego, E.; Lorente, A.; Ibanez F, S.; Vega C, H. R.; Gonzalez, J. A.; Mendez, R.

2016-10-01

In homeland security, neutron detection is used to prevent the smuggling of special nuclear materials. Thermal neutrons are normally detected with "3He proportional counters, in the radiation portal monitors, Rpms, however due to the "3He shortage new procedures are being studied. In this work Monte Carlo methods, using the MCNP6 code, have been used to study the neutron detection features of a "1"0B+ZnS(Ag) under real conditions inside of a Rpm. The performance for neutron detection was carried out for "2"5"2Cf, "2"3"8U and "2"3"9Pu under different conditions. In order to mimic an actual situation occurring at border areas, a sample of SNM sited inside a vehicle was simulated and the Rpm with "1"0B+ZnS(Ag) response was calculated. At 200 cm the "1"0B+ZnS(Ag) on Rpm response is close to 2.5 cps-ng "2"5"2Cf, when the "2"5"2Cf neutron source is shielded with 0.5 cm-thick lead and 2.5 cm-thick polyethylene fulfilling the ANSI recommendations. Three different geometries of neutron detectors of "1"0B+ZnS(Ag) in a neutron detection system in Rpm were modeled. Therefore, the "1"0B+ZnS(Ag) detectors are an innovative and viable replacement for the "3He detectors in the Rpm. (Author)

Influence of Ce-H bonding on the physical properties of the hydrides CeCoSiH1.0 and CeCoGeH1.0

International Nuclear Information System (INIS)

Chevalier, B; Matar, S F; Menetrier, M; Marcos, J Sanchez; Fernandez, J Rodriguez

2006-01-01

The hydrides CeCoSiH 1.0 and CeCoGeH 1.0 which crystallize like the parent antiferromagnetic compounds CeCoSi and CeCoGe in the tetragonal CeFeSi-type structure, have been investigated by specific heat and thermoelectric power measurements and 1 H nuclear magnetic resonance (NMR). CeCoSiH 1.0 is an intermediate valence compound whereas CeCoGeH 1.0 can be considered as a nearly trivalent cerium compound. This behaviour is corroborated by the occurrence of a slight broadening of the 1 H NMR signal in the sequence CeCoSiH 1.0 → CeCoGeH 1.0 . The band structure calculations performed on these hydrides reveal the existence of strong bonding Ce-H interaction, found to be larger in CeCoSiH 1.0 than in CeCoGeH 1.0

Transport Phenomena In Single Crystals Tl1−XIn1−XGeXSe2 (x=0.1, 0.2

Directory of Open Access Journals (Sweden)

Zamurueva O.V.

2015-09-01

Full Text Available Temperature dependences of electroconductivity for single crystals Tl1−xIn1−xGexSe2 were analyzed. It was established an occurrence of thermoactivated states within the temperature range 100-300 K. The conductivity is formed by delocalized carriers within the conductivity band and the jumping conductivity over the localized states which are situated in the narrow localized states near the Fermi level. Following the performed data the activation energy was evaluated with accuracy up to 0.02 eV. The density of the localized states as well as the distribution of the energy over the mentioned states was evaluated. Additionally the average distance between the localized states is evaluated at different temperatures.

Records of performance and sanitary status from a dairy cattle herd in southern Brazil

Directory of Open Access Journals (Sweden)

Cláudio E. F. Cruz

2011-01-01

Full Text Available Over the last decades, the emphasis on the health of dairy cows has changed from an individual to a herd level. In this scenario, the role played by the recording system and its interpretation by veterinarians has gained primordial importance. The records of productive and reproductive performance and of sanitary status from a southern Brazilian dairy cattle herd have been presented and discussed. The period of study was 2000-2009. Mean values per lactation period were 349D 8436M 290F 275P 201SCS (D: days in lactation, M: kg of milk yield, F: kg of fat, P: kg of protein and SCS: somatic cell score in 1000 cells/ml of milk. Major indexes of reproductive efficiency included age at first calving (31 months, services per conception (2.1, intercalving interval (428 days, calving to conception interval (146 days, mean annual rates of parturitions (76.2%, fetal losses (9.8-19.0%, and stillbirths (3.6%, apart of voluntary waiting period (94 days. Main information on sanitary status of the herd was associated with the mean prevalence of common disorders of dairy cattle such as anaplasmosis (29.8%, mastitis (27.8%, digital diseases (26.3%, ovarian cysts (21.3%, placental retention (19.7%, postpartum uterine infections (10.6%, and calf diarrhea (23.7% and pneumonia (16.8%, among others. In addition, culling reasons (low reproductive performance [56.3%] and udder/mastitis problems [33.6%], causes of cattle deaths (anaplasmosis [16.4%] and leukosis [11.4], and the impact of cattle diseases such as tuberculosis, leukosis, and neosporosis on the herd have also been presented and succinctly discussed. Numbers between brackets represent rates accumulated in the 10-year period.

26 CFR 1.338-0 - Outline of topics.

Science.gov (United States)

2010-04-01

... specific insurance contracts. (c) Application of assumption reinsurance principles. (1) In general. (2... contained in the regulations under section 338 as follows: § 1.338-1General principles; status of old target and new target. (a) In general. (1) Deemed transaction. (2) Application of other rules of law. (3...

Composite cathode La0.15Bi0.85O1.5-Ag for intermediate-temperature solid oxide fuel cells

International Nuclear Information System (INIS)

Gao Zhan; Mao Zongqiang; Huang Jianbing; Gao Ruifeng; Wang Cheng; Liu Zhixiang

2008-01-01

Composites consisting of silver and lanthanum stabilized bismuth oxide (La 0.15 Bi 0.85 O 1.5 ) were investigated as cathodes for intermediate-temperature solid oxide fuel cells with doped ceria as electrolyte. No stable phases were formed via reaction between La 0.15 Bi 0.85 O 1.5 and Ag. The microstructure of the interfaces between composite cathodes and Ce 0.8 Sm 0.2 O 1.5 electrolytes was studied by scanning electron microscopy after sintering at various temperatures. Impedance spectroscopy measurements revealed that the performance of cathode fired at 700 deg. C was the best. When the optimum fraction of Ag was 50 vol.%, polarization resistance values for the LSB-Ag50 cathode were as low as 0.14 Ω cm 2 at 700 deg. C and 0.18 Ω cm 2 at 650 deg. C. The steady-state polarization investigations on LSB and LSB-Ag50 cathodes were performed using typical three-electrode test cells in air. The results showed that the LSB-Ag50 composite cathode exhibited a lower overpotential and higher exchange current density than LSB, which indicated the electrochemical performance of LSB-Ag50 for the oxygen reduction reaction was superior to the LSB

Neutron diffraction and magnetic study of the Nd0.7Pb0.3Mn1-xFexO3 (0=0.1) perovskites

International Nuclear Information System (INIS)

Blanco, J.J.; Insausti, M.; Gil de Muro, I.; Lezama, L.; Rojo, T.

2006-01-01

The effect of Fe doping on the ferromagnetic Nd 0.7 Pb 0.3 Mn 1-x Fe x O 3 (x=0, 0.025, 0.05, 0.075, 0.1) phases has been studied in order to analyze the double-exchange interaction. The structural and magnetic study has been carried out by neutron powder diffraction and susceptibility measurements between 1.7 and 300K. The substitution of Fe at the Mn site results in reductions in both the Curie temperature T c and the magnetic moment per Mn ion without appreciable differences in the crystal structures. All the compounds crystallize in Pnma space group. The thermal evolution of the lattice parameters of the Nd 0.7 Pb 0.3 Mn 1-x Fe x O 3 (x=0.025, 0.05, 0.075) compounds shows discontinuities in volume and lattice parameters close to the magnetic transition temperature. Increasing amounts of Fe 3+ reduces the double exchange interactions and no magnetic contribution for x=0.1 is observed. The magnetic structures of Nd 0.7 Pb 0.3 Mn 1-x Fe x O 3 (x=0, 0.025, 0.05, 0.075) compounds show that the Nd and Mn ions are ferromagnetically ordered

Microhardness and fracture toughness of Ce0.9Gd0.1O1.95 for manufacturing solid oxide electrolytes

International Nuclear Information System (INIS)

Mangalaraja, R.V.; Ananthakumar, S.; Uma, Kasimayan; Jimenez, Romel M.; Lopez, Marta; Camurri, Carlos P.

2009-01-01

Synthesis of nanocrystalline gadolinium doped ceria (Ce 0.9 Gd 0.1 O 1.95 ) was attempted by nitrate-fuel combustion technique involving different organic fuels namely urea, citric acid, glycine and poly ethylene glycol. As-combusted ceria precursors were calcined at 700 deg. C for 2 h for obtaining fully dense, nanocrystalline ceria powders. Cylindrical ceria discs were fabricated by uni-axial pressing and sintered intentionally at low temperature of 1200 deg. C for 2 h for assessing the sintering characteristics of the nano powders as well as the mechanical performance of the sintered ceria body. The study confirms that the nano powders could be sintered to 98% theoretical sintered density at 1200 deg. C with a grain size of 400 nm to 1 μm. The sintered samples exhibited the Vickers microhardness of 8.82 ± 0.2 GPa and the fracture toughness of 1.75 ± 0.3 MPa m 1/2 at a load 20 N for glycine and citric acid fuels derived ceria, respectively. A comparison between the fuels was made with respect to the sintering and mechanical properties of doped ceria. Citric acid and glycine fuels resulted in sintered ceria with high hardness where as the urea and polyethylene fuels derived nano ceria resulted in high fracture toughness.

Study of the ηc(1 1S0) state of charmonium formed in bar pp annihilations and a search for the ηc'(2 1S0)

International Nuclear Information System (INIS)

Armstrong, T.A.; Bettoni, D.; Bharadwaj, V.; Biino, C.; Blanford, G.; Borreani, G.; Broemmelsiek, D.; Buzzo, A.; Calabrese, R.; Ceccucci, A.; Cester, R.; Church, M.; Dalpiaz, P.; Dalpiaz, P.F.; Dimitroyannis, D.; Fabbri, M.; Fast, J.; Gianoli, A.; Ginsburg, C.M.; Gollwitzer, K.; Govi, G.; Hahn, A.; Hasan, M.; Hsueh, S.; Lewis, R.; Luppi, E.; Macri, M.; Majewska, A.M.; Mandelkern, M.; Marchetto, F.; Marinelli, M.; Marques, J.; Marsh, W.; Martini, M.; Masuzawa, M.; Menichetti, E.; Migliori, A.; Mussa, R.; Palestini, S.; Pallavicini, M.; Passaggio, S.; Pastrone, N.; Patrignani, C.; Peoples, J. Jr.; Petrucci, F.; Pia, M.G.; Pordes, S.; Rapidis, P.; Ray, R.; Reid, J.; Rinaudo, G.; Roccuzzo, B.; Rosen, J.; Santroni, A.; Sarmiento, M.; Savrre, M.; Schultz, J.; Seth, K.K.; Smith, A.; Smith, G.A.; Sozzi, M.; Trokenheim, S.; Weber, M.F.; Werkema, S.; Zhang, Y.; Zhao, J.; Zioulas, G.

1995-01-01

The E760 Collaboration performed an experiment in the Antiproton Accumulator at Fermilab to study the two photon decay of the η c (1 1 S 0 ) charmonium state formed in bar pp annihilations. This resulted in a new measurement of the mass M ηc =2988.3 -3.1 +3.3 MeV/c 2 and of the product B(η c → bar pp)xΓ(η c →γγ) =(8.1 -2.0 +2.9 ) eV. We performed a search for the process bar pp→η c ' (2 1 S 0 )→γγ over a limited range of center-of-mass energies. Since no signal was observed, we derived upper limits on the product of branching ratios B(η c ' → bar pp)xB(η c ' →γγ) in the center-of-mass energy range 3584≤ √s ≤3624 MeV. We observed no signal for the nonresonant process bar p+p→γ+γ and obtain upper limits

1.0 Introduction

African Journals Online (AJOL)

She now sees herself as marginalised by both her male-counterpart as well .... the concepts and theories which are used (explicitly or implicitly) to make ... boldly challenged the status quo by attacking the bases of cultural attitudes on the.

Microstructure evolution and large magnetocaloric effect of La0.8Ce0.2(Fe0.95Co0.05)11.8Si1.2 alloy prepared by strip-casting and annealing

Science.gov (United States)

Zhong, X. C.; Feng, X. L.; Huang, J. H.; Zhang, H.; Huang, Y. L.; Liu, Z. W.; Jiao, D. L.

2018-04-01

The microstructure and magnetocaloric effect of the La0.8Ce0.2(Fe0.95Co0.05)11.8Si1.2 strip-cast flakes annealed between 1273K and 1423K for different time have been investigated. For the flakes annealed for 2h from 1273K to 1423K, the shape and distribution of α-Fe, La-rich and NaZn13-type 1:13 phases are quite sensitive to the annealing temperature. Especially, at a high annealing temperature of 1423K, the 1:13 phase began to decompose into macroscopic α-Fe conglomerations and La-rich dendrites. With the increase of annealing time from 0 to 12h at 1323K, the amount of 1:13 phase increased significantly and reached ˜93.50 wt.% at 12h. However, an overlong annealing time also led to 1:13 phase decomposition and influenced the magnetic performance. For the flakes annealed at 1323K for 12h, large magnetic entropy change value of 18.12Jkg-1K-1 at 5T has been obtained. The present results indicate that strip casting method can potentially be used in mass production of high performance magnetocaloric materials.

Comprehensive methods to enhance the electrochemical performances of LiFe0.94Mg0.03Cu0.03PO4/C cathode for lithium ion batteries

International Nuclear Information System (INIS)

Fan, Chang-ling; Zhang, Ke-he; Han, Shao-chang

2013-01-01

Graphical abstract: Relationships between the conductivities of LFPC-2 cathode and the volume percentages of AB (a) and PAn (b). - Highlights: • LiFe 0.94 Mg 0.03 Cu 0.03 PO 4 /C is synthesized by adding glucose with two-step method. • Conductive polymer polyaniline is used to replace acetylene black. • The content of conductive additive is optimized by the percolation theory. • LFPC-2 cathode containing polyaniline possesses the excellent performance. - Abstract: Comprehensive methods were utilized to improve the electrochemical performances of LiFe 0.94 Mg 0.03 Cu 0.03 PO 4 /C (LFPC) composite cathode. Experimental results show that LFPC-2, prepared by adding glucose in two steps, possesses the effective incorporated of doping ions and well-distributed pyrolysis carbon. It possesses higher conductivity and discharge capacity. The percolation theory analysis shows that the conductivity of LFPC-2 cathode film reaches its maximum value at the mass content of 15 wt.%. The replacement of acetylene black with polyaniline can greatly improve the electrochemical performances of LFPC-2 cathode. Its discharge capacity is 85.3 mAh g −1 and its potential platform is as high as 3.2 V at the current density of 850 mA g −1 when 15 wt.% polyaniline is used. The cycle performance of LFPC-2 is improved when polyaniline is used as conductive additives. And the change of charge transfer resistance of LFPC-2 cathode containing polyaniline is very small after 24 cycles

Watertrak, a computerized liquid waste treatment system status and performance monitoring program

International Nuclear Information System (INIS)

Vance, J.N.; Tafazzoli, M.M.

1984-01-01

Because of continuing problems in the radwaste system operations of a large number of plants currently operating, there is an increasing need to provide greater quantities of radwaste system information to plant operators and managers. Current and more complete information is required to enhance the operation and performance of the radwaste treatment systems, to assess the current system status, to plan for changing plant conditions and to diagnose actual or impending problems. The information needs include: real-time system status monitoring, equipment performance monitoring, report generation for operators and plant management, and training information. The nature and quantity of information required makes this program well-suited for a computer-aided engineering application

Methylation status of the APC and RASSF1A promoter in cell-free circulating DNA and its prognostic role in patients with colorectal cancer.

Science.gov (United States)

Matthaios, Dimitrios; Balgkouranidou, Ioanna; Karayiannakis, Anastasios; Bolanaki, Helen; Xenidis, Nikolaos; Amarantidis, Kyriakos; Chelis, Leonidas; Romanidis, Konstantinos; Chatzaki, Aikaterini; Lianidou, Evi; Trypsianis, Grigorios; Kakolyris, Stylianos

2016-07-01

DNA methylation is the most frequent epigenetic alteration. Using methylation-specific polymerase chain reaction (MSP), the methylation status of the adenomatous polyposis coli ( APC ) and Ras association domain family 1 isoform A ( RASSF1A ) genes was examined in cell-free circulating DNA from 155 plasma samples obtained from patients with early and advanced colorectal cancer (CRC). APC and RASSF1A hypermethylation was frequently observed in both early and advanced disease, and was significantly associated with a poorer disease outcome. The methylation status of the APC and RASSF1A promoters was investigated in cell-free DNA of patients with CRC. Using MSP, the promoter methylation status of APC and RASSF1A was examined in 155 blood samples obtained from patients with CRC, 88 of whom had operable CRC (oCRC) and 67 had metastatic CRC (mCRC). The frequency of APC methylation in patients with oCRC was 33%. Methylated APC promoter was significantly associated with older age (P=0.012), higher stage (P=0.014) and methylated RASSF1A status (P=0.050). The frequency of APC methylation in patients with mCRC was 53.7%. In these patients, APC methylation was significantly associated with methylated RASSF1A status (P=0.016). The frequency of RASSF1A methylation in patients with oCRC was 25%. Methylated RASSF1A in oCRC was significantly associated with higher stage (P=0.021). The frequency of RASSF1A methylation in mCRC was 44.8%. Methylated RASSF1A in mCRC was associated with moderate differentiation (P=0.012), high levels of carcinoembryonic antigen (P=0.023) and methylated APC status (P=0.016). Patients with an unmethylated APC gene had better survival in both early (81±5 vs. 27±4 months, PAPC . Patients with an unmethylated RASSF1A gene had better survival in both early (71±6 vs. 46±8 months, PAPC and RASSF1A promoter methylation status and survival may be indicative of a prognostic role for these genes in CRC, which requires additional testing in larger studies.

Vitamin supplementation and related nutritional status in Thai children, aged 1-5 years.

Science.gov (United States)

Ratanachu-ek, Suntaree

2014-06-01

To evaluate the prevalence of vitamin supplementation in Thai children aged 1-5 years at Queen Sirikit National Institute of Child Health (QSNICH), parental knowledge of vitamins, practices, and related factors such as nutritional status in vitamin supplementation. A cross-sectional study was performed at the Well Child Clinic, QSNICH, from 1-31 May 2005. Five hundred parents of young children, aged 1-5 years were interviewed by using the questionnaire to obtain information regarding knowledge and practices of vitamin supplementation. Weight and length/height were measured and nutritional status was assessed using the Thai growth reference. The relationships among vitamin supplement, nutritional status, and other related factors were analyzed using Chi-square test. The p-value vitamin supplementation was 76%, including vitamin C 62%, multi-vitamin (MTV) 35%, and cod-liver oil 20%. Regarding parental knowledge of vitamins, 57% of them knew the health benefits but 74% did not know the toxic effects of vitamins. The reasons for vitamin supplementation were poor feeding 63%, under-weight 23% and unhealthy status 14%. Vitamins were obtained from over-the-counter 59%, health services 40%, and friends 1%. Vitamin supplementation was significantly higher in children over 2 years of age, whose parents knew the benefits of vitamins, and in those children with malnutrition. The prevalence of vitamin supplementation was high in malnourished children, over 2 years of age whose parents had knowledge about benefits of vitamins. Parents should be warned about the dangers of high dose of vitamin consumption.

Paraoxonase 1 (PON1) status and substrate hydrolysis

International Nuclear Information System (INIS)

Richter, Rebecca J.; Jarvik, Gail P.; Furlong, Clement E.

2009-01-01

Paraoxonase 1 (PON1) hydrolyzes a number of organophosphorus (OP) compounds including insecticides and nerve agents. The in vivo efficacy of PON1 to protect against a specific OP exposure depends on the catalytic efficiency of hydrolysis. The Q192R polymorphism affects the catalytic efficiency of hydrolysis of some substrates and not others. While PON1 R192 hydrolyzes paraoxon approximately 9-times as efficiently as PON1 Q192 , the efficiency is insufficient to provide in vivo protection against paraoxon/parathion exposure. The two PON1 192 alloforms have nearly equivalent but higher catalytic efficiencies for hydrolyzing diazoxon (DZO) and provide equivalent in vivo protection against DZO exposures. On the other hand, PON1 R192 is significantly more efficient in hydrolyzing chlorpyrifos oxon (CPO) than PON1 Q192 and provides better protection against CPO exposure. Thus, for some exposures it is only the level of plasma PON1 that is important, whereas for others it is both plasma level and the PON1 192 alloform(s) present in plasma that are important. In no case is the plasma level of PON1 unimportant, provided that the catalytic efficiency is sufficient to protect against the exposure. Two-substrate enzyme assay/analysis protocols that reveal both PON1 plasma levels and PON1 192 phenotype (QQ; QR; RR) are designed to optimize the separation of PON1 192 phenotypes; however, they have not been optimized for evaluating in vivo rates of OP detoxication. This study describes the adaptation of a non-OP, two-substrate determination of PON1 status to the conversion of the PON1 status data to physiologically relevant rates of DZO and CPO detoxication. Conversion factors were generated for rates of hydrolysis of different substrates

The effects of individual status and group performance on network ties among teammates in the National Basketball Association.

Directory of Open Access Journals (Sweden)

Jeremy Koster

Full Text Available For individuals, status is derived both from their personal attributes and the groups with whom they are affiliated. Depending on the performance of their groups, the status of individuals may benefit or suffer from identifying closely with the group. When the group excels, high-status members potentially receive much of the credit and increased status. Conversely, high-status members of underperforming groups potentially suffer disproportionate declines in their status relative to the low-status group members. We therefore predict an interaction between group performance and individual status on the willingness to associate with the group and its members. We test our prediction by examining social media ties among teammates in the National Basketball Association. Specifically, we investigate the "following" ties of teammates on Twitter at the end of the 2014-2015 season. Elections to All-Star games are used to measure the status of players, and team performance is measured by recent success in the postseason playoffs. The results show that compared to high-status players on successful teams, high-status players on underperforming teams are less likely to follow their teammates. This result aligns with research on status inconsistency, suggesting that individuals deemphasize their group affiliation when it jeopardizes their individual status. An additional contribution is the advancement of the probit Social Relations Model for the analysis of binary ties in social networks.

The effects of individual status and group performance on network ties among teammates in the National Basketball Association.

Science.gov (United States)

Koster, Jeremy; Aven, Brandy

2018-01-01

For individuals, status is derived both from their personal attributes and the groups with whom they are affiliated. Depending on the performance of their groups, the status of individuals may benefit or suffer from identifying closely with the group. When the group excels, high-status members potentially receive much of the credit and increased status. Conversely, high-status members of underperforming groups potentially suffer disproportionate declines in their status relative to the low-status group members. We therefore predict an interaction between group performance and individual status on the willingness to associate with the group and its members. We test our prediction by examining social media ties among teammates in the National Basketball Association. Specifically, we investigate the "following" ties of teammates on Twitter at the end of the 2014-2015 season. Elections to All-Star games are used to measure the status of players, and team performance is measured by recent success in the postseason playoffs. The results show that compared to high-status players on successful teams, high-status players on underperforming teams are less likely to follow their teammates. This result aligns with research on status inconsistency, suggesting that individuals deemphasize their group affiliation when it jeopardizes their individual status. An additional contribution is the advancement of the probit Social Relations Model for the analysis of binary ties in social networks.

Low-temperature growth of (2 1-bar 1-bar 0) ZnO nanofilm on NaCl (0 0 1) surface by ion beam sputtering

International Nuclear Information System (INIS)

Shen, Jung-Hsiung; Yeh, Sung-Wei; Huang, Hsing-Lu; Gan, Dershin

2009-01-01

ZnO nanofilm of the (2 1 -bar 1 -bar 0) surface was prepared by ion beam sputtering deposition. The nanofilm was prepared on NaCl (0 0 1) surface at 200 o C to produce nearly pure (2 1 -bar 1 -bar 0) ZnO texture and the orientation relationship was determined and the interface discussed. Transmission electron microscopy lattice images were used to find the interface formed between ZnO nanocrystals. The ZnO nanocrystals coalesced to form a straight (0 1 -bar 1 -bar 2) interface. The photoluminescence spectrum from the (2 1 -bar 1 -bar 0) ZnO surface showed only a near-band-edge UV emission peak.

Histone H1(0) mapping using monoclonal antibodies.

Science.gov (United States)

Dousson, S; Gorka, C; Gilly, C; Lawrence, J J

1989-06-01

Monoclonal antibodies (mAb) to ox liver histone H1 degree were produced and characterized. Two sets of mice were immunized either with pure H1(0) or with an H1(0)-yeast tRNA complex. Eleven hybridomas of various clonal origin were selected. Typing of the antibodies indicated that all but three IgM belonged to the IgG1 class and contained kappa light chains. Immunoblotting experiments using peptides derived from H1(0) or H5 treated by various proteolytic agents (trypsin, N-bromosuccinimide, cyanogen bromide, acetic acid), revealed that nine of the mAb reacted with the globular part of H1(0). More advanced characterization of the antigenic determinants allowed us to determine distinct regions within this globular part which are involved in the antigenic recognition. The peptopes could be subdivided into two groups. Three mAb bound to residues 24-27 and were specific for H1(0). Six mAb bound to residues 27-30 and were specific for H1(0) except one of them which strongly cross-reacted with H5 and GH5. Two mAb reacted with the entire histone H1(0) but failed to react with any of the peptides, suggesting that the corresponding epitope is a conformational antigenic determinant. In order to confirm the localization of the two distinct regions which are involved in the antigenic recognition, a synthetic decapeptide corresponding to the beginning of human H1(0) globular part (from residue 19 to residue 28) was synthesized. Inhibition experiments of the reaction between H1(0) and the various IgG1 mAb by increasing amounts of peptide-bovine serum albumin conjugates were then performed.

The growth of Zn on a Si(1 0 0)-2x1 surface

International Nuclear Information System (INIS)

Xie Zhaoxiong; Tanaka, Ken-ichi

2005-01-01

Adsorption of Zn atoms on a Si(1 0 0)-2x1 surface was studied by scanning tunneling microscopy at room temperature. Narrow lines are grown perpendicular to the Si-dimer rows of the [1 1 0] direction at low coverage. The narrow line is formed by arraying rectangular Zn 3 dots, where a dot is composed of one Zn atom on a Si dimer and the other two in the neighboring two hollow sites. When the Si(1 0 0)-2x1 surface is covered with one monolayer of Zn, a 4x1 structure is established. More deposition of Zn on the 4x1 monolayer grows into three-dimensional Zn islands

Effect of thermal treatment on the characteristics of iridium Schottky barrier diodes on n-Ge (1 0 0)

Energy Technology Data Exchange (ETDEWEB)

Chawanda, A., E-mail: albert.chawanda@up.ac.za [Department of Physics, University of Pretoria, 0002 (South Africa); Department of Physics, Midlands State University, Bag 9055, Gweru (Zimbabwe); Coelho, S.M.M.; Auret, F.D.; Mtangi, W. [Department of Physics, University of Pretoria, 0002 (South Africa); Nyamhere, C. [Department of Physics, Nelson Mandela Metropolitan University, Box 77000, Port Elizabeth 6031 (South Africa); Nel, J.M.; Diale, M. [Department of Physics, University of Pretoria, 0002 (South Africa)

2012-02-05

Highlights: Black-Right-Pointing-Pointer Ir/n-Ge (1 0 0) Schottky diodes were characterized using I-V, C-V and SEM techniques under various annealing conditions. Black-Right-Pointing-Pointer The variation of the electrical and structural properties can be due to effects phase transformation during annealing. Black-Right-Pointing-Pointer Thermal stability of these diodes is maintained up to 500 Degree-Sign C anneal. Black-Right-Pointing-Pointer SEM results depicts that the onset temperature for agglomeration in 20 nm Ir/n-Ge (1 0 0) system occurs between 600 and 700 Degree-Sign C. - Abstract: Iridium (Ir) Schottky barrier diodes were deposited on bulk grown (1 0 0) Sb-doped n-type germanium by using the electron beam deposition system. Electrical characterization of these contacts using current-voltage (I-V) and capacitance-voltage (C-V) measurements was performed under various annealing conditions. The variation of the electrical properties of these Schottky diodes can be attributed to combined effects of interfacial reaction and phase transformation during the annealing process. Thermal stability of the Ir/n-Ge (1 0 0) was observed up to annealing temperature of 500 Degree-Sign C. Furthermore, structural characterization of these samples was performed by using a scanning electron microscopy (SEM) at different annealing temperatures. Results have also revealed that the onset temperature for agglomeration in a 20 nm Ir/n-Ge (1 0 0) system occurs between 600 and 700 Degree-Sign C.

Jump test performance and sarcopenia status in men and women, 55 to 75 years of age.

Science.gov (United States)

Singh, Harshvardhan; Kim, Daeyeol; Kim, Eonho; Bemben, Michael G; Anderson, Mark; Seo, Dong-Il; Bemben, Debra A

2014-01-01

Jumping mechanography uses maximal countermovement jumps to test obtain such as jump power (JPow). Recently, it has been shown to be a safe method for assessing muscle function in older adults; however, little is known about the relationships between JPow, muscle strength, and sarcopenia status. The purpose of this study was to examine jump performance, muscle strength, and sarcopenia status in older adults. This was a cross-sectional study that included men (n = 27) and women (n = 33) (55-75 years) recruited from the general community. Participants completed health status and physical activity questionnaires. Body composition, including appendicular skeletal muscle mass (ASM), bone free lean body mass, and relative skeletal muscle mass index, were assessed by total body dual-energy x-ray absorptiometry scans. The criteria for sarcopenia were relative skeletal muscle mass index values less than 7.26 kg/m2 for men and less than 5.45 kg/m2 for women. Three vertical jumps on a jump mat were performed to assess JPow, jump velocity (JVel), and jump height (JHt). Muscle strength was measured by 1RM testing for leg press (LP) and right and left hip abduction isotonic resistance exercises. Sarcopenia was found in 20% (12/60) of the participants. Jump power was significantly lower (P = .001) in the sarcopenia group than in the normal group, 651.1 (41.7) W versus 851.0 (27.4) W, respectively. Jump power and JHt were significantly (P mass. Significant (P muscle strength (LP, right and left hip abduction). The jump test protocol was conducted safely with no injuries or balance issues. Our finding of lower JPow in sarcopenic individuals adds new information to the existing literature on age-related declines in muscle power. Community-dwelling individuals classified as sarcopenic had significantly lower JPow but not muscle strength compared with their counterparts with normal amounts of muscle mass. Jump test variables were positively correlated with lean tissue and lower body

Tunnel magnetoresistance in trilayer junctions from first principles: Cr δ-layer doped GaN/AlN/GaN (0 0 0 1)

International Nuclear Information System (INIS)

Cui, X.Y.; Delley, B.; Freeman, A.J.; Stampfl, C.

2010-01-01

The microscopic mechanism of the tunneling magnetoresistance (TMR) in Cr-doped GaN/AlN/GaN (0 0 0 1) trilayer junctions is studied based on density functional theory calculations. For enhanced performance, we propose δ-Cr-layer doping in GaN, close to the GaN/AlN interfaces. Depending on the doping concentration, Cr dopants produce local metallic (1 ML) or half-metallic (1/2 and 1/4 ML) states surrounded by the host semiconductor materials. Very thin AlN barriers are predicted to yield a low TMR effect. These results help explain existing experimental results and are expected to be valuable with regard to the practical fabrication of improved pure semiconductor spintronic devices.

Helicobacter pylori seropositivity's association with markers of iron, 1-carbon metabolism, and antioxidant status among US adults: a structural equations modeling approach.

Directory of Open Access Journals (Sweden)

May A Beydoun

Full Text Available We tested a model in which Helicobacter pylori seropositivity (Hps predicted iron status, which in turn acted as a predictor for markers of 1-C metabolism that were then allowed to predict antioxidant status.National Health and Nutrition Examination Surveys (NHANES 1999-2000 cross-sectional data among adults aged 20-85 y were analyzed (n = 3,055. Markers of Hps, iron status (serum ferritin and transferrin saturation (TS; 1-C metabolism (serum folate (FOLserum, B-12, total homocysteine (tHcy, methylmalonic acid (MMA and antioxidant status (vitamins A and E were entered into a structural equations model (SEM.Predictors of Hps included older age, lower education and income, racial/ethnic groups (lowest among Non-Hispanic Whites, and lifetime cigarette smoking. SEM modeling indicated that Hps had a direct inverse relationship with iron status (combining serum ferritin and TS which in turn was positively related to 1-C metabolites (higher serum folate, B-12 or lower tHcy/MMA that were positively associated with antioxidant status (combining serum vitamins A and E. Another pathway that was found bypassed 1-C metabolites (Hps → Iron_st → Antiox. The sum of all indirect effects from Hps combining both pathways and the other indirect pathways in the model (Hps → Iron_st → OneCarbon; Hps →OneCarbon →Antiox was estimated at β = -0.006±0.003, p<0.05.In sum, of the total effect of H. pylori seropositivity on antioxidant status, two significant indirect pathways through Iron status and 1-Carbon metabolites were found. Randomized controlled trials should be conducted to uncover the concomitant causal effect of H. pylori eradication on improving iron status, folate, B-12 and antioxidant status among H. pylori seropositive individuals.

Improving La0.6Sr0.4Co0.8Fe0.2O3-δ infiltrated solid oxide fuel cell cathode performance through precursor solution desiccation

Science.gov (United States)

Burye, Theodore E.; Nicholas, Jason D.

2015-02-01

Here, for the first time, the average size of solid oxide fuel cell (SOFC) electrode nano-particles was reduced through the chemical desiccation of infiltrated precursor nitrate solutions. Specifically, after firing at 700 °C, CaCl2-desiccated La0.6Sr0.4Co0.8Fe0.2O3-δ (LSCF) - Ce0.9Gd0.1O1.95 (GDC) cathodes contained LSCF infiltrate particles with an average size of 22 nm. This is in contrast to comparable, undesiccated LSCF-GDC cathodes which contained LSCF infiltrate particles with an average size of 48 nm. X-ray diffraction, scanning electron microscopy, and controlled atmosphere electrochemical impedance spectroscopy revealed that desiccation reduced the average infiltrate particle size without altering the infiltrate phase purity, the cathode concentration polarization resistance, or the cathode electronic resistance. Compared to undesiccated LSCF-GDC cathodes achieving polarization resistances of 0.10 Ωcm2 at 640 °C, comparable CaCl2-dessicated LSCF-GDC cathodes achieved 0.10 Ωcm2 at 575 °C. Mathematical modeling suggested that these performance improvements resulted solely from average infiltrate particle size reductions.

Synthesis and thermoelectric performance of a p-type Bi0.4Sb1.6Te3 material developed via mechanical alloying

International Nuclear Information System (INIS)

Jimenez, Sandra; Perez, Jose G.; Tritt, Terry M.; Zhu, Song; Sosa-Sanchez, Jose L.; Martinez-Juarez, Javier; López, Osvaldo

2014-01-01

Highlights: • This paper shows a Bi 1.6 Sb 0.4 Te 3 alloy prepared by MA-SPS process. • A ZT value of about 1.2–1.3 around 360 K was achieved for this compound. • The lower sintering process was carried out in a short time. • The resulting material has a very fine microstructure and high density. - Abstract: A p-type Bi 0.4 Sb 1.6 Te 3 thermoelectric compound was fabricated via mechanical alloying of bismuth, antimony and tellurium elemental powders as starting materials. The mechanically alloyed compositions were sintered through a spark-plasma sintering (SPS) process. The effect of the milling time was investigated. In order to characterize the powders obtained via mechanical alloying, X-ray diffraction (XRD) and energy dispersive spectroscopy (EDS) analysis were used. The morphological evolution was studied by scanning electron microscopy (SEM). Results showed that the p-type Bi 0.4 Sb 1.6 Te 3 compound was formed after 2 h of milling. Further, the variation of milling time showed that the synthesized phase was stable. All the powders exhibit the same morphology albeit with slight differences. Measurements of the electrical resistivity, Seebeck coefficient and thermal conductivity were performed in the temperature range 300–520 K for the SPS samples. The resulting thermoelectric figure of merit ZT reaches a maximum of 1.2 at 360 K for the p-type bulk material with a 5 h milling time. This study demonstrates the possibility of preparing thermoelectric materials of high performance and short processing time

Comparison of clinical and radiographic status around dental implants placed in patients with and without prediabetes: 1-year follow-up outcomes.

Science.gov (United States)

Al Amri, Mohammad D; Abduljabbar, Tariq S; Al-Kheraif, Abdulaziz A; Romanos, Georgios E; Javed, Fawad

2017-02-01

We hypothesized that peri-implant soft tissue inflammation is worse and peri-implant marginal bone loss (MBL) is higher around dental implants placed in patients with prediabetes compared to healthy subjects. The aim of the present 12-month follow-up study was to compare the clinical and radiographic status around dental implants placed in patients with and without prediabetes. Twelve patients with medically diagnosed prediabetes (Group-1) and 12 controls (Group-2) were included. All patients were indicated for single tooth maxillary or mandibular premolar replacement with the adjacent teeth intact. Success of the restored implants was assessed by comparing clinical (peri-implant bleeding on probing [BOP], and probing pocket depth [PPD]) and radiographic (peri-implant MBL) parameters at baseline and at 12-months follow-up. Statistical analysis was performed using one-way analysis of variance, and P-values implant pockets with PPD ≥ 4 mm in both groups. At 12-month follow-up, the mean MBL among implants placed in groups 1 and 2 were 0.2 ± 0.1 mm and 0.1 ± 0.01 mm, respectively. Overall, the periodontal status (PI, BOP and PPD ≥ 4 mm) at 12-month follow-up was comparable among patients in both groups. Within the limitations of this study, it is concluded that dental implants inserted in prediabetic and healthy patients have similar success rates and remain clinically and radiographically stable after 1-year follow-up. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Relative efficiency calibration between two silicon drift detectors performed with a monochromatized X-ray generator over the 0.1-1.5 keV range

Science.gov (United States)

Hubert, S.; Boubault, F.

2018-03-01

In this article, we present the first X-ray calibration performed over the 0.1-1.5 keV spectral range by means of a soft X-ray Manson source and the monochromator SYMPAX. This monochromator, based on a classical Rowland geometry, presents the novelty to be able to board simultaneously two detectors and move them under vacuum in front of the exit slit of the monochromatizing stage. This provides the great advantage to perform radiometric measurements of the monochromatic X-ray photon flux with one reference detector while calibrating another X-ray detector. To achieve this, at least one secondary standard must be operated with SYMPAX. This paper presents thereby an efficiency transfer experiment between a secondary standard silicon drift detector (SDD), previously calibrated on BESSY II synchrotron Facility, and another one ("unknown" SDD), devoted to be used permanently with SYMPAX. The associated calibration process is described as well as corresponding results. Comparison with calibrated measurements performed at the Physikalisch-Technische Bundesanstalt (PTB) Radiometric Laboratory shows a very good agreement between the secondary standard and the unknown SDD.

CONPAS 1.0 (CONtainment Performance Analysis System). User's manual

International Nuclear Information System (INIS)

Ahn, Kwang Il; Jin, Young Ho

1996-04-01

CONPAS (CONtainment Performance Analysis System) is a verified computer code package to integrate the numerical, graphical, and results-operation aspects of Level 2 probabilistic safety assessments (PSA) for nuclear power plants automatically under a PC window environment. Compared with the existing DOS-based computer codes for Level 2 PSA, the most important merit of the window-based computer code is that user can easily describe and quantify the accident progression models, and manipulate the resultant outputs in a variety of ways. As a main logic for accident progression analysis, CONPAS employs a concept of the small containment phenomenological event tree (CPET) helpful to trace out visually individual accident progressions and of the large supporting event tree (LSET) for its detailed quantification. For the integrated analysis of Level 2 PSA, the code utilizes four distinct, but closely related modules; (1) ET Editor for construction of several event tree models describing the accident progressions, (2) Computer for quantification of the constructed event trees and graphical display of the resultant outputs, (3) Text Editor for preparation of input decks for quanification and utilization of calculational results, and (4) Mechanistic Code Plotter for utilization of results obtained from severe accident analysis codes. Compared with other existing computer codes for Level 2 PSA, the CONPAS code provides several advanced features: computational aspects including systematic uncertainty analysis, importance analysis, sensitivity analysis and data interpretation, reporting aspects including tabling and graphic as well as user-friend interface. 10 refs. (Author) .new

Effects of feeding lutein on production performance, antioxidative status, and milk quality of high-yielding dairy cows.

Science.gov (United States)

Xu, C Z; Wang, H F; Yang, J Y; Wang, J H; Duan, Z Y; Wang, C; Liu, J X; Lao, Y

2014-11-01

This experiment was conducted to determine the influences of supplementing different levels of an additive containing lutein in the diet of Chinese Holstein lactating cows on production performance, antioxidative plasma metabolites, and milk quality. This study was performed on 60 multiparous Holstein dairy cows in peak lactation. The cows were randomly allocated to 1 of 4 homogeneous treatments, with lutein preparation (extracted from marigolds; effective lutein content was 2%) added at levels of 0, 100, 150, and 200 g/d per head, with the actual available amounts being 0, 2, 3, and 4 g of lutein/d per head, respectively. The experiment lasted for 13 wk, with the first week for adaptation. Milk yield and milk compositions were recorded weekly, and milk concentrations of lutein, dry matter intake, and antioxidative blood index were analyzed in the first, fourth, seventh, and thirteenth week of the study. The results showed that adding lutein in the diet had no effect on dry matter intake compared with the control group; however, it slowed down the trend of decline in milk yield, and had a linear incremental effect on milk yield with increasing concentration of lutein. Dietary lutein tended to quadratically increase the percentage of milk fat, and linearly increased milk lactose concentration, with the highest value when treated at 200 g of lutein preparation/d per head, and decreased somatic cell count, with the lowest values when treated with 150 and 200 g of lutein preparation/d per head. The concentration of lutein in milk linearly increased with the incorporation of the additive, with a value of 0.59, 0.70, 1.20, and 1.50 μg/100mL when treated with 0, 100, 150, and 200 g/d, respectively. Total plasma antioxidant capacity tended to linearly increase in cows fed lutein preparation, whereas plasma superoxide dismutase and glutathione peroxidase activities did not differ significantly. In conclusion, addition of lutein in the diet could improve the production

Far infrared near normal specular reflectivity of Nix(SiO2)1-x (x = 1.0, 0.84, 0.75, 0.61, 0.54, 0.28) granular films

KAUST Repository

Massa, Néstor E.

2010-04-01

One of the current issues at the basis of the understanding of novel materials is the degree of the role played by spatial inhomogeneities due to subtle phase separations. To clarify this picture here we compare the plain glass network response of transition metal granular films with different metal fractions against what is known for conducting oxides. Films for Nix(SiO2)1-x (x = 1.0, 0.84, 0.75, 0.61, 0.54, 0.28) were studied by temperature dependent far infrared measurements. While for pure Ni the spectrum shows a flat high reflectivity, those for x ∼ 0.84 and ∼0.75 have a Drude component, vibrational modes mostly carrier screened, and a long tail that extents toward near infrared. This is associated with hopping electron conductivity and strong electron-phonon interactions. The relative reduction of the number of carriers in Ni0.75(SiO2)0.25 allows less screened phonon bands on the top of a continuum and a wide and overdamped oscillator at mid-infrared frequencies. Ni0.54(SiO2)0.46 and Ni0.28(SiO2)0.72 have well defined vibrational bands and a sharp threshold at ∼1450 cm-1. It is most remarkable that a distinctive resonant peak at ∼1250 cm-1 found for p-polarized angle dependent specular reflectivity. It originates in an electron cloud traced to electrons that are not able to overcome the metal-dielectric interface that, beating against the positive background, generates the electric dipole. Overall, we conclude that the spectra are analogous to those regularly found in conducting oxides where with a suitable percolating network polarons are formed. © 2009 Elsevier B.V. All rights reserved.

Hierarchical Ni0.54Co0.46O2 nanowire and nanosheet arrays grown on carbon fiber cloth for high-performance supercapacitors

Science.gov (United States)

Jiang, Yuanzhi; Zhang, Lijuan; Zhang, Hang; Zhang, Cui; Liu, Shuangxi

2016-10-01

Hierarchical Ni0.54Co0.46O2 architectures composed by nanowires or nanosheets were successfully grown on bio-mass carbon fiber cloth (CFC) by hydrothermal method. The morphology of Ni0.54Co0.46O2 can be effectively controlled by using different precipitators. The structural effects of the two kinds of morphologies were researched. the results suggest that the Ni0.54Co0.46O2 nanosheet arrays grown on CFC (NCO-NSs/CFC) shows a higher Faradaic areal capacity of 438 μAh cm-2 (238.1 mAh g-1) at a current density of 1 mA cm-2 and still about 90.3% initial capacity retention even at the high current density of 50 mA cm-2. Moreover, an all-solid-state flexible symmetric supercapacitor device has been successfully assembled. The optimized device delivers superior electrochemical performance with an outstanding energy density of 92.4 Wh kg-1 at a power density of 207.2 W kg-1. Such hierarchical nanostructure composed by well-aligned uniform Ni0.54Co0.46O2 nanosheet arrays grown on bio-mass carbon fiber cloth might hold great promise as battery-type electrode material for high-performance supercapacitor.

User's guide for PRISM (Plant Risk Status Information Management System) Arkansas Nuclear One-Unit 1: Volume 1, Program for inspectors

International Nuclear Information System (INIS)

Campbell, D.J.; Guthrie, V.H.; Kirchner, J.R.; Kirkman, J.Q.; Paula, H.M.; Ellison, B.C.; Dycus, F.M.; Farquharson, J.A.; Flanagan, G.F.

1988-03-01

This user's guide is a two-volume document designed to teach NRC inspectors and NRC regulators how to access probabilistic risk assessment information from the two Plant Risk Status Information Management System (PRISIM) programs developed for Arkansas Nuclear One -- Unit One (ANO-1). This document, Volume 1, describes how the PRA information available in Version 1.0 of PRISIM is useful for planning inspections. Using PRISIM, inspectors can quickly access PRA information and use that information to update risk analysis results, reflecting a plant's status at any particular time. Both volumes are stand-alone documents, and each volume presents several sample computer sessions designed to lead the user through a variety of PRISIM applications used to obtain PRA-related information for monitoring and controlling plant risk

Effect of selenium supplementation on pigeon reproductive performance, selenium concentration and antioxidant status.

Science.gov (United States)

Wang, Y; Yang, H M; Cao, W; Li, Y B

2017-09-01

The effects of dietary supplementation of sodium selenite (SS) on the reproductive performance and the concentration of selenium, glutathione peroxidase (GSH-Px), superoxide dismutase (SOD), and malondialdehyde (MDA) were determined, and expression of glutathione peroxidase 4 (GPx4) and bone morphogenic protein 15 (BMP15) was evaluated. Paired pigeons (n = 864) were fed: T1 received no SS, while T2, T3, and T4 received 0.5, 1.0, and 1.5 mg of SS/kg of dry matter (DM), respectively. Treatments were performed in triplicate with 72 pairs in each replicate. The results showed that selenium supplementation significantly affected pigeon reproductive performance. Birds fed 1.0 mg of SS/kg displayed higher egg production (P > 0.05), higher birth rate, and lower dead sperm rate than the control group (P Selenium and biochemical analyses revealed a higher selenium concentration in the 1.5 mg of SS/kg group than in the control group (P  0.05); however, in plasma, MDA was lower in the control group (P  0.05), while in ovary, BMP15 was down-regulated in the 1.5 mg of SS/kg group (P selenium concentration, and 0.5 mg of SS/kg up-regulated GSH-Px activity. © 2017 Poultry Science Association Inc.

Oral health status in diabetic children

International Nuclear Information System (INIS)

Iqbal, S.; Qureshi, A.; Iqbal, N.; Khan, A.A.

2006-01-01

Diabetes causes numerous oral and salivary changes leading to cariogenic and gingival lesions. The present study was designed to elucidate the role of diabetes mellitus in oral health. A cross-sectional study including 60 diabetic children (case group) and 30 non diabetic children (control group) of age 3-14 years was conducted. HbA1c and blood glucose level was measured along with the oral health including gingival status and dental caries status was visually assessed. Gingival status was coded for healthy, marginal gingivitis and calculus. Dental caries status (decayed and filled) for both deciduous and permanent dentition was assessed. Data was recorded in a pre-coded oral health proforma, which was then entered and analyzed in SPSS version 10.0. Descriptive analysis such as percentage frequencies and means was performed. Exact Chi-square test was used to analyze any significant changes observed amongst the study population, where level of significance was p < 0.05 with confidence interval 95%. The results show important difference between both groups of children. Dental caries level is significantly higher in diabetic children both in deciduous and permanent dentition than in non-diabetic children (p <0.05). Gingival health was also observed to be debilitated in diabetic children than nondiabetic children (p < 0.05). Conclusion: The study highlights that special preventive measures must be adopted to maintain a good oral health of the diabetic children. (author)

A Study on BRCA1/2 Mutations, Hormone Status and HER-2 Status in Korean Women with Early-onset Breast Cancer

International Nuclear Information System (INIS)

Choi, Doo Ho; Jin, So Young; Lee, Dong Wha; Kim, Eun Seog; Kim, Yong Ho

2008-01-01

Women with breast cancer diagnosed at an age of 40 years or younger have a greater prevalence of germline BRCA1 and BRCA2 mutations than the prevalence of women with breast cancer diagnosed at older ages. Several immunohistochemical characteristics have been identified in breast cancers from studies of Caucasian women with BRCA1/2 mutations having familial or early-onset breast cancers. The aim of this study is to determine whether early-onset breast cancer in BRCA1 or BRCA2 mutation carriers, who were not selected from a family history, could be distinguished by the use of immunohistochemical methods and could be distinguished from breast cancer in women of a similar age without a germline BRCA1 or BRCA2 mutation. We also analyzed the prognostic difference between BRCA1/2 related and BRCA1/2 non-related patients by the use of univariate and multivariate analysis. Breast cancer tissue specimens from Korean women with early-onset breast cancers were studied using a tumor tissue microarray. Immunohistochemical staining of estrogen receptor (ER), progesterone receptor (PR) and HER-2, as well as the histology and grade of these specimens, were compared. The prognostic impact of immunohistochemical and histological factors as well as the BRCA1/2 mutation status was investigated separately. There were 14 cases and 16 deleterious BRCA1/2 mutations among 101 patients tested. A family history (4/14) and bilateral breast cancers (3/9) were high risk factors for BRCA1/2 mutations. BRCA1/2- associated cancers demonstrated more expression of ER-negative (19.4% versus 5.1%, p=0.038) and HER-2 negative than BRCA1/2 negative tumors, especially for tumors with BRCA1 tumors The BRCA1/2 mutation rate for patients with triple negative tumors (negative expression of ER, PR and HER-2) was 24.2%. Tumor size, nodal status, and HER-2 expression status were significantly associated with disease free survival, as determined by univariate and multivariate analysis, but the BRCA1/2 status was

The Effects of Solo Status on Women's and Men's Success: The Moderating Role of the Performance Context

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Viallon, Marie-Laure; Martinot, Delphine

2009-01-01

A considerable body of research has shown that being the only representative of one's gender group (solo status) when performing an activity affects women more than men. The aim of our two experiments was to show that the performance context can moderate the effects of numerical status (majority vs. solo) on performance and that men can also be…

The effects of fatty fish intake on adolescents' nutritional status and associations with attention performance: results from the FINS-TEENS randomized controlled trial.

Science.gov (United States)

Handeland, Katina; Skotheim, Siv; Baste, Valborg; Graff, Ingvild E; Frøyland, Livar; Lie, Øyvind; Kjellevold, Marian; Markhus, Maria W; Stormark, Kjell M; Øyen, Jannike; Dahl, Lisbeth

2018-02-23

Adolescence involves changes in dietary habits that may induce imbalances in the intake of different nutrients. Fish is an important dietary source of omega-3 (n-3) long-chain polyunsaturated fatty acids (LCPUFAs), vitamin D, several minerals and high-quality protein. By using secondary outcomes and exploratory analyses, the aims of this paper were to evaluate if nutritional biomarkers (red blood cell fatty acids, serum (s)-25(OH)D, s-ferritin and urinary iodine concentration (UIC)) were altered during a dietary intervention, and if they mediated previously reported changes in attention performance. In addition, to examine the status of the biomarkers and explore associations between dietary pattern, biomarkers and attention performance cross-sectionally at baseline. The Fish Intervention Studies-TEENS (FINS-TEENS) was a three-armed intervention trial, including adolescents from eight secondary schools (n = 415; age: 14-15y) in Bergen, Norway. Participants were individually randomized to receive either fish meals, meat meals or n-3 LCPUFA supplements, three times a week for a total of 12 weeks. Blood and urine samples were collected pre and post intervention and attention performance was assessed with the d2 test of attention. Analyses of covariance (ANCOVA) assessed differences between groups in changes of biomarkers and linear mixed models were applied in analyses of attention performance and biomarkers. The trial is registered in ClinicalTrials.gov (NCT02350322). At baseline, the mean omega-3 index was 5.8 ± 1.3% and deficient status were identified for s-25(OH)D (54%), s-ferritin (10%) and UIC (40%). The intervention resulted in an increase in DHA and the omega-3 index which was larger in the supplement group compared to the fish and meat group (P < 0.01), and in the fish group compared to the meat group (P < 0.01). No differences between the groups were observed for changes in 25(OH)D, s-ferritin or UIC. None of the biomarkers mediated

Water formation via HCl oxidation on Cu(1 0 0)

Energy Technology Data Exchange (ETDEWEB)

Suleiman, Ibrahim A., E-mail: isuleman@taibahu.edu.sa [College of Engineering, Taibah University, Yanbu 41911 (Saudi Arabia); Radny, Marian W. [School of Mathematical and Physical Sciences, The University of Newcastle, Callaghan, NSW 2308 (Australia); Institute of Physics, Poznan University of Technology, 62-956 Poznan (Poland); Gladys, Michael J.; Smith, Phillip V. [School of Mathematical and Physical Sciences, The University of Newcastle, Callaghan, NSW 2308 (Australia); Mackie, John C. [School of Engineering, The University of Newcastle, Callaghan, NSW 2308 (Australia); School of Chemistry, The University of Sydney (Australia); Stockenhuber, Michael; Kennedy, Eric M. [School of Engineering, The University of Newcastle, Callaghan, NSW 2308 (Australia); Dlugogorski, Bogdan Z. [School of Engineering, The University of Newcastle, Callaghan, NSW 2308 (Australia); School of Engineering and Information Technology, Murdoch University, Perth (Australia)

2014-04-01

Graphical abstract: This work investigates water formation on the Cu(1 0 0) surface via HCl oxidation using density functional theory and periodic slabs. We show that there are two different pathways for water formation on the surface depending on the temperature and oxygen coverage. - Highlights: • Pre-adsorbed chlorine increases the stability of water on Cu(1 0 0). • Two different pathways describe water formation on Cu(1 0 0) via HCl oxidation. • The mechanism of H{sub 2}O formation depends on the temperature and oxygen coverage. - Abstract: Using density functional theory and periodic slabs, we have studied water formation via HCl oxidation on the Cu(1 0 0) surface. We show that while adsorbed chlorine increases the stability of water on the Cu(1 0 0) surface, water molecules dissociate immediately when located next to an oxygen atom. We also show that these competing interactions, when arising from HCl reacting with oxygen on Cu(1 0 0), lead to water formation according to two different pathways depending on the temperature and oxygen coverage.

The impact of prenatal employment on breastfeeding intentions and breastfeeding status at 1 week postpartum.

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Attanasio, Laura; Kozhimannil, Katy B; McGovern, Patricia; Gjerdingen, Dwenda; Johnson, Pamela Jo

2013-11-01

Postpartum employment is associated with non-initiation and early cessation of breastfeeding, but less is known about the relationship between prenatal employment and breastfeeding intentions and behaviors. This study aimed to estimate the relationship between prenatal employment status, a strong predictor of postpartum return to work, and breastfeeding intentions and behaviors. Using data from the Listening to Mothers II national survey (N = 1573), we used propensity score matching methods to account for non-random selection into employment patterns and to measure the impact of prenatal employment status on breastfeeding intentions and behaviors. We also examined whether hospital practices consistent with the Baby-Friendly Hospital Initiative (BFHI), assessed based on maternal perception, were differentially associated with breastfeeding by employment status. Women who were employed (vs unemployed) during pregnancy were older, were more educated, were less likely to have had a previous cesarean delivery, and had fewer children. After matching, these differences were eliminated. Although breastfeeding intention did not differ by employment, full-time employment (vs no employment) during pregnancy was associated with decreased odds of exclusive breastfeeding 1 week postpartum (adjusted odds ratio = 0.48; 95% confidence interval, 0.25-0.92; P = .028). Higher BFHI scores were associated with higher odds of breastfeeding at 1 week but did not differentially impact women by employment status. Women employed full-time during pregnancy were less likely to fulfill their intention to exclusively breastfeed, compared to women who were not employed during pregnancy. Clinicians should be aware that employment circumstances may impact women's breastfeeding decisions; this may help guide discussions during clinical encounters.

Performance Evaluation of the Bioneer AccuPower® HIV-1 Quantitative RT-PCR kit: Comparison with the Roche COBAS® AmpliPrep/COBAS TaqMan® HIV-1 Test Ver.2.0 for Quantification of HIV-1 Viral Load in Indonesia.

Science.gov (United States)

Kosasih, Agus Susanto; Sugiarto, Christine; Hayuanta, Hubertus Hosti; Juhaendi, Runingsih; Setiawan, Lyana

2017-08-08

Measurement of viral load in human immunodeficiency virus type 1 (HIV-1) infected patients is essential for the establishment of a therapeutic strategy. Several assays based on qPCR are available for the measurement of viral load; they differ in sample volume, technology applied, target gene, sensitivity and dynamic range. The Bioneer AccuPower® HIV-1 Quantitative RT-PCR is a novel commercial kit that has not been evaluated for its performance. This study aimed to evaluate the performance of the Bioneer AccuPower® HIV-1 Quantitative RT-PCR kit. In total, 288 EDTA plasma samples from the Dharmais Cancer Hospital were analyzed with the Bioneer AccuPower® HIV-1 Quantitative RT-PCR kit and the Roche COBAS? AmpliPrep/COBAS® TaqMan® HIV-1 version 2.0 (CAP/CTM v2.0). The performance of the Bioneer assay was then evaluated against the Roche CAP/CTM v2.0. Overall, there was good agreement between the two assays. The Bioneer assay showed significant linear correlation with CAP/CTM v2.0 (R2=0.963, plaboratories.

Matrix metalloproteinase-9 predicts pulmonary status declines in α1-antitrypsin deficiency

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Rames Alexis

2011-03-01

Full Text Available Abstract Background Matrix metalloproteinase-9 (MMP-9 may be important in the progression of emphysema, but there have been few longitudinal clinical studies of MMP-9 including pulmonary status and COPD exacerbation outcomes. Methods We utilized data from the placebo arm (n = 126 of a clinical trial of patients with alpha1-antitrypsin deficiency (AATD and emphysema to examine the links between plasma MMP-9 levels, pulmonary status, and COPD exacerbations over a one year observation period. Pulmonary function, computed tomography lung density, incremental shuttle walk test (ISWT, and COPD exacerbations were assessed at regular intervals over 12 months. Prospective analyses used generalized estimating equations to incorporate repeated longitudinal measurements of MMP-9 and all endpoints, controlling for age, gender, race-ethnicity, leukocyte count, and tobacco history. A secondary analysis also incorporated highly-sensitive C-reactive protein levels in predictive models. Results At baseline, higher plasma MMP-9 levels were cross-sectionally associated with lower FEV1 (p = 0.03, FVC (p Conclusions Increased plasma MMP-9 levels generally predicted pulmonary status declines, including worsening transfer factor and lung density as well as greater COPD exacerbations in AATD-associated emphysema.

Nanopowders Y1−yNdyV1−xCrxO4 with y=0 and 1; x=0, 0.1, 0.2 and 0.5 synthesized by a sol–gel process. Relationship between morphological characteristics and optical properties

International Nuclear Information System (INIS)

Alcaraz, L.; Isasi, J.; Caballero, A.C.; Izquierdo, J.G.; Bañares, L.

2015-01-01

Y 1−y Nd y V 1−x Cr x O 4 nanopowders with y=0 and 0.1; x=0, 0.1, 0.2 and 0.5, have been synthetized by a sol–gel process followed by heating in an oxygen flow. This second treatment was done only in the case of samples containing chromium. The samples have been characterized by X-ray diffraction (XRD), Fourier Transform Infrared (FTIR) spectroscopy, scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The structural analysis revealed that when chromium was inserted at vanadium-sites in Y 0.9 Nd 0.1 VO 4 , the host retained the tetragonal symmetry corresponding to a zircon-type structure, attributed to the space group I4 1 /amd. In addition, a loss of crystallinity was observed when chromium substitutes vanadium into the Y 0.9 Nd 0.1 VO 4 host. The morphological studies revealed agglomerates of spherical particles whose size is increased with the Cr content and confirmed the composition of all synthetized samples. FTIR spectra of these samples exhibit a broadening and a slight shift of the bands around 830 cm −1 towards higher values of frequency when the chromium content increases. The effect of vanadium substitution by chromium on the optical properties was also evaluated by UV–vis absorption and photoluminescence (PL) spectroscopies. The broad UV band absorption is due to the presence of Cr 5+ . A decrease of PL emission is found when chromium substitutes vanadium in the YVO 4 host. - Highlights: • Nanophosphors Y 1−y Nd y V 1−x Cr x O 4 with y=0, 0.1 and x=0, 0.1, 0.2 and 0.5 have been synthesized. • Structural analysis reveals structural distortions associated to chromium insertion. • Morphological studies confirm the nanocristalline size and the stoichiometry of synthesized samples. • Chromium insertion causes a decrease of the PL emission intensity

Pengetahuan Ibu Tentang Pertumbuhan Berhubungan dengan Status Gizi Anak Usia 0-59 Bulan di Wilayah Kerja Puskesmas Banguntapan I Bantul, Yogyakarta

Directory of Open Access Journals (Sweden)

Rikardus Nendi Irwanto

2016-03-01

Full Text Available One of the stated goals of MDGs is to eradicate extreme poverty and hunger. The higher the poverty and hunger of a country will have an impact on the health, welfare and food consumption of malnourished people, especially in toddlers. Nutrition necessity is main concern that must be considered in their growth. Nutrition can determine the level of children’s health. Good growth is not only physical growth but also their mental and intellectual development that is also expected to develop well. Therefore it becomes prevalent growth. The purpose of study was to know the relationship between mother’s knowledge on growth and children’s nutrient status aged 0-59 months in working area of Puskesmas Banguntapan I Bantul. The method was descriptive analytical research using cross sectional design and data research analysis of spearman rho. The sample collection was cluster sampling with lottery. Results showed that mother’s knowledge on growth was in good category 55.1% and less category 3.4%. Meanwhile, the nutrient status of children at age 0-59 months was in good category 70.8% and very thin category 3.4%. In conclusion, there was a relationship between mother’s knowledge on growth and children’s nutrient status aged 0-59 months in working area of Puskesmas Banguntapan I Bantul (p-value=0,000.

Associations of Youth and Parent Weight Status with Reported versus Predicted Daily Energy Intake and Hemoglobin A1c in Youth with Type 1 Diabetes Mellitus

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Sands, Amanda L. P.; Higgins, Laurie A.; Mehta, Sanjeev N.; Nansel, Tonja R.; Lipsky, Leah M.; Laffel, Lori M. B.

2013-01-01

Background The epidemic of overweight/obesity affects youth with type 1 diabetes mellitus (T1DM) and their families. In youth with T1DM and their parents, we examined weight status with reported and expected energy intake and with youth hemoglobin A1c (HbA1c). Methods In 243 youth (48% female, 13 ± 3 years) and their parents (84% female, 45 ± 6 years), we assessed body mass index (BMI), prevalence of overweight/obesity, reported energy intake (REI), and youth glycemic control (HbA1c). The REI was compared with predicted daily energy requirements (DER; based on age, weight, sex, and physical activity). Results Youth had diabetes duration of 6.3 ± 3.4 years and HbA1c of 8.5% ± 1.3%; 69% used insulin pump therapy. Overweight and obesity affected 23% and 11% of youth and 30% and 24% of parents, respectively. Youth and parent BMI (r = 0.38; p obese; p obese compared with underweight/normal weight parents (1.0 ± 0.4 versus 1.2 ± 0.5; p = .001) but did not differ among youth by weight status. Both youth and parent BMI were positively correlated with youth HbA1c (r = 0.14, p = .02; r = 0.16, p = .01, respectively). Hemoglobin A1c tended to be higher in obese than in overweight and normal weight youth (mean ± standard deviation [SD] 8.4 ± 1.4, 8.4 ± 1.3, and 8.8 ± 1.0, respectively; p = .06) and was significantly higher in youth whose parents were obese versus overweight or underweight/normal weight (mean ± SD 8.2 ± 1.2, 8.5 ± 1.4, and 8.9 ± 1.5, respectively; p obesity are prevalent among families of youth with T1DM. Weight status appears to influence self-REI in parents and glycemic control in youth with T1DM, suggesting the need for family-based dietary interventions. PMID:23439184