WorldWideScience

Sample records for perfect gt repeats

  1. Construction of Subgame-Perfect Mixed Strategy Equilibria in Repeated Games

    NARCIS (Netherlands)

    Berg, Kimmo; Schoenmakers, Gijsbertus

    2017-01-01

    This paper examines how to construct subgame-perfect mixed-strategy equilibria in discounted repeated games with perfect monitoring.We introduce a relatively simple class of strategy profiles that are easy to compute and may give rise to a large set of equilibrium payoffs. These sets are called

  2. Exogenous empirical-evidence equilibria in perfect-monitoring repeated games yield correlated equilibria

    KAUST Repository

    Dudebout, Nicolas; Shamma, Jeff S.

    2014-01-01

    This paper proves that exogenous empirical-evidence equilibria (xEEEs) in perfect-monitoring repeated games induce correlated equilibria of the associated one-shot game. An empirical-evidence equilibrium (EEE) is a solution concept for stochastic games. At equilibrium, agents' strategies are optimal with respect to models of their opponents. These models satisfy a consistency condition with respect to the actual behavior of the opponents. As such, EEEs replace the full-rationality requirement of Nash equilibria by a consistency-based bounded-rationality one. In this paper, the framework of empirical evidence is summarized, with an emphasis on perfect-monitoring repeated games. A less constraining notion of consistency is introduced. The fact that an xEEE in a perfect-monitoring repeated game induces a correlated equilibrium on the underlying one-shot game is proven. This result and the new notion of consistency are illustrated on the hawk-dove game. Finally, a method to build specific correlated equilibria from xEEEs is derived.

  3. Exogenous empirical-evidence equilibria in perfect-monitoring repeated games yield correlated equilibria

    KAUST Repository

    Dudebout, Nicolas

    2014-12-15

    This paper proves that exogenous empirical-evidence equilibria (xEEEs) in perfect-monitoring repeated games induce correlated equilibria of the associated one-shot game. An empirical-evidence equilibrium (EEE) is a solution concept for stochastic games. At equilibrium, agents\\' strategies are optimal with respect to models of their opponents. These models satisfy a consistency condition with respect to the actual behavior of the opponents. As such, EEEs replace the full-rationality requirement of Nash equilibria by a consistency-based bounded-rationality one. In this paper, the framework of empirical evidence is summarized, with an emphasis on perfect-monitoring repeated games. A less constraining notion of consistency is introduced. The fact that an xEEE in a perfect-monitoring repeated game induces a correlated equilibrium on the underlying one-shot game is proven. This result and the new notion of consistency are illustrated on the hawk-dove game. Finally, a method to build specific correlated equilibria from xEEEs is derived.

  4. GT-repeat polymorphism in the heme oxygenase-1 gene promoter is associated with cardiovascular mortality risk in an arsenic-exposed population in northeastern Taiwan

    International Nuclear Information System (INIS)

    Wu, Meei-Maan; Chiou, Hung-Yi; Chen, Chi-Ling; Wang, Yuan-Hung; Hsieh, Yi-Chen; Lien, Li-Ming; Lee, Te-Chang; Chen, Chien-Jen

    2010-01-01

    Inorganic arsenic has been associated with increased risk of atherosclerotic vascular disease and mortality in humans. A functional GT-repeat polymorphism in the heme oxygenase-1 (HO-1) gene promoter is inversely correlated with the development of coronary artery disease and restenosis after clinical angioplasty. The relationship of HO-1 genotype with arsenic-associated cardiovascular disease has not been studied. In this study, we evaluated the relationship between the HO-1 GT-repeat polymorphism and cardiovascular mortality in an arsenic-exposed population. A total of 504 study participants were followed up for a median of 10.7 years for occurrence of cardiovascular deaths (coronary heart disease, cerebrovascular disease, and peripheral arterial disease). Cardiovascular risk factors and DNA samples for determination of HO-1 GT repeats were obtained at recruitment. GT repeats variants were grouped into the S (< 27 repeats) or L allele (≥ 27 repeats). Relative mortality risk was estimated using Cox regression analysis, adjusted for competing risk of cancer and other causes. For the L/L, L/S, and S/S genotype groups, the crude mortalities for cardiovascular disease were 8.42, 3.10, and 2.85 cases/1000 person-years, respectively. After adjusting for conventional cardiovascular risk factors and competing risk of cancer and other causes, carriers with class S allele (L/S or S/S genotypes) had a significantly reduced risk of cardiovascular mortality compared to non-carriers (L/L genotype) [OR, 0.38; 95% CI, 0.16-0.90]. In contrast, no significant association was observed between HO-1 genotype and cancer mortality or mortality from other causes. Shorter (GT)n repeats in the HO-1 gene promoter may confer protective effects against cardiovascular mortality related to arsenic exposure.

  5. Construction of Subgame-Perfect Mixed-Strategy Equilibria in Repeated Games

    Directory of Open Access Journals (Sweden)

    Kimmo Berg

    2017-11-01

    Full Text Available This paper examines how to construct subgame-perfect mixed-strategy equilibria in discounted repeated games with perfect monitoring. We introduce a relatively simple class of strategy profiles that are easy to compute and may give rise to a large set of equilibrium payoffs. These sets are called self-supporting sets, since the set itself provides the continuation payoffs that are required to support the equilibrium strategies. Moreover, the corresponding strategies are simple as the players face the same augmented game on each round but they play different mixed actions after each realized pure-action profile. We find that certain payoffs can be obtained in equilibrium with much lower discount factor values compared to pure strategies. The theory and the concepts are illustrated in 2 × 2 games.

  6. Surface antigens and potential virulence factors from parasites detected by comparative genomics of perfect amino acid repeats

    Directory of Open Access Journals (Sweden)

    Adler Joël

    2007-12-01

    Full Text Available Abstract Background Many parasitic organisms, eukaryotes as well as bacteria, possess surface antigens with amino acid repeats. Making up the interface between host and pathogen such repetitive proteins may be virulence factors involved in immune evasion or cytoadherence. They find immunological applications in serodiagnostics and vaccine development. Here we use proteins which contain perfect repeats as a basis for comparative genomics between parasitic and free-living organisms. Results We have developed Reptile http://reptile.unibe.ch, a program for proteome-wide probabilistic description of perfect repeats in proteins. Parasite proteomes exhibited a large variance regarding the proportion of repeat-containing proteins. Interestingly, there was a good correlation between the percentage of highly repetitive proteins and mean protein length in parasite proteomes, but not at all in the proteomes of free-living eukaryotes. Reptile combined with programs for the prediction of transmembrane domains and GPI-anchoring resulted in an effective tool for in silico identification of potential surface antigens and virulence factors from parasites. Conclusion Systemic surveys for perfect amino acid repeats allowed basic comparisons between free-living and parasitic organisms that were directly applicable to predict proteins of serological and parasitological importance. An on-line tool is available at http://genomics.unibe.ch/dora.

  7. ChloroSSRdb: a repository of perfect and imperfect chloroplastic simple sequence repeats (cpSSRs) of green plants.

    Science.gov (United States)

    Kapil, Aditi; Rai, Piyush Kant; Shanker, Asheesh

    2014-01-01

    Simple sequence repeats (SSRs) are regions in DNA sequence that contain repeating motifs of length 1-6 nucleotides. These repeats are ubiquitously present and are found in both coding and non-coding regions of genome. A total of 534 complete chloroplast genome sequences (as on 18 September 2014) of Viridiplantae are available at NCBI organelle genome resource. It provides opportunity to mine these genomes for the detection of SSRs and store them in the form of a database. In an attempt to properly manage and retrieve chloroplastic SSRs, we designed ChloroSSRdb which is a relational database developed using SQL server 2008 and accessed through ASP.NET. It provides information of all the three types (perfect, imperfect and compound) of SSRs. At present, ChloroSSRdb contains 124 430 mined SSRs, with majority lying in non-coding region. Out of these, PCR primers were designed for 118 249 SSRs. Tetranucleotide repeats (47 079) were found to be the most frequent repeat type, whereas hexanucleotide repeats (6414) being the least abundant. Additionally, in each species statistical analyses were performed to calculate relative frequency, correlation coefficient and chi-square statistics of perfect and imperfect SSRs. In accordance with the growing interest in SSR studies, ChloroSSRdb will prove to be a useful resource in developing genetic markers, phylogenetic analysis, genetic mapping, etc. Moreover, it will serve as a ready reference for mined SSRs in available chloroplast genomes of green plants. Database URL: www.compubio.in/chlorossrdb/ © The Author(s) 2014. Published by Oxford University Press.

  8. detectIR: a novel program for detecting perfect and imperfect inverted repeats using complex numbers and vector calculation.

    Science.gov (United States)

    Ye, Congting; Ji, Guoli; Li, Lei; Liang, Chun

    2014-01-01

    Inverted repeats are present in abundance in both prokaryotic and eukaryotic genomes and can form DNA secondary structures--hairpins and cruciforms that are involved in many important biological processes. Bioinformatics tools for efficient and accurate detection of inverted repeats are desirable, because existing tools are often less accurate and time consuming, sometimes incapable of dealing with genome-scale input data. Here, we present a MATLAB-based program called detectIR for the perfect and imperfect inverted repeat detection that utilizes complex numbers and vector calculation and allows genome-scale data inputs. A novel algorithm is adopted in detectIR to convert the conventional sequence string comparison in inverted repeat detection into vector calculation of complex numbers, allowing non-complementary pairs (mismatches) in the pairing stem and a non-palindromic spacer (loop or gaps) in the middle of inverted repeats. Compared with existing popular tools, our program performs with significantly higher accuracy and efficiency. Using genome sequence data from HIV-1, Arabidopsis thaliana, Homo sapiens and Zea mays for comparison, detectIR can find lots of inverted repeats missed by existing tools whose outputs often contain many invalid cases. detectIR is open source and its source code is freely available at: https://sourceforge.net/projects/detectir.

  9. Association of heme oxygenase-1 GT-repeat polymorphism with blood pressure phenotypes and its relevance to future cardiovascular mortality risk: an observation based on arsenic-exposed individuals.

    Science.gov (United States)

    Wu, Meei-Maan; Chiou, Hung-Yi; Chen, Chi-Ling; Hsu, Ling-I; Lien, Li-Ming; Wang, Chih-Hao; Hsieh, Yi-Chen; Wang, Yuan-Hung; Hsueh, Yu-Mei; Lee, Te-Chang; Cheng, Wen-Fang; Chen, Chien-Jen

    2011-12-01

    Heme oxygenase (HO)-1 is up-regulated as a cellular defense responding to stressful stimuli in experimental studies. A GT-repeat length polymorphism in the HO-1 gene promoter was inversely correlated to HO-1 induction. Here, we reported the association of GT-repeat polymorphism with blood pressure (BP) phenotypes, and their interaction on cardiovascular (CV) mortality risk in arsenic-exposed cohorts. Associations of GT-repeat polymorphism with BP phenotypes were investigated at baseline in a cross-sectional design. Effect of GT-repeat polymorphism on CV mortality was investigated in a longitudinal design stratified by hypertension. GT-repeat variants were grouped by S (accounting for CV covariates. Totally, 894 participants were recruited and analyzed. At baseline, carriers with HO-1 S alleles had lower diastolic BP (L/S genotypes, P = 0.014) and a lower possibility of being hypertensive (L/S genotypes, P = 0.048). After follow-up, HO-1 S allele was significantly associated with a reduced CV risk in hypertensive participants [relative mortality ratio (RMR) 0.27 (CI 0.11, 0.69), P = 0.007] but not in normotensive. Hypertensive participants without carrying the S allele had a 5.23-fold increased risk [RMR 5.23 (CI 1.99, 13.69), P = 0.0008] of CV mortality compared with normotensive carrying the S alleles. HO-1 short GT-repeat polymorphism may play a protective role in BP regulation and CV mortality risk in hypertensive individuals against environmental stressors. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  10. GT-MHR project

    International Nuclear Information System (INIS)

    Kiryushin, A.; Kodochigov, N.

    2002-01-01

    The paper presents new generation reactor - modular helium reactor with gas turbine (GT-MHR), which satisfies the requirements of the developing nuclear power. The paper describes the reactor plant and peculiarities of GT-MHR technical concept, such as high efficiency (about 48%) of electric power generation, increased safety of the plant, etc. The technologies, which are the innovative essence of GT-MHR project, are: (1) fuel in the form of fuel particles with multi-layer ceramic coatings which confine fission products at high temperatures (of about 1600 deg.); (2) large gas turbines; (3) single-shaft vertical turbomachine design; (4) electromagnetic bearings; (5) high-effective compact heat exchangers. Main technical and economical indices of GT-MHR project are presented. (author)

  11. Main: GT1CONSENSUS [PLACE

    Lifescience Database Archive (English)

    Full Text Available m of GT-1 may be achieved through direct interaction between TFIIA and GT-1; Binding of GT-1-like factors to the PR-1a promoter influ...ences the level of SA-inducible gene expression; GT-1; light; TATA; TFIIA; TBP; HR;

  12. Picture perfect

    DEFF Research Database (Denmark)

    Pless, Mette; Sørensen, Niels Ulrik

    ’Picture perfect’ – when perfection becomes the new normal This paper draws on perspectives from three different studies. One study, which focuses on youth life and lack of well-being (Sørensen et al 2011), one study on youth life on the margins of society (Katznelson et al 2015) and one study...

  13. Asymmetric GT of social networks

    Science.gov (United States)

    Szu, Harold

    2010-04-01

    Web citation indexes are computed according to a data vector X collected from the frequency of user accesses, citations weighted by other sites' popularities, and modified by the financial sponsorship in a proprietary manner. The indexing determining the information to be retrieved by the public should be made responsible transparently in at least two ways. One shall balance the inbound linkages pointed at the specific i-th site called the popularity (see paper for equation) with the outbound linkages (see paper for equation) called the risk factor before the release of new information as environmental impact analysis. The relationship between these two factors cannot be assumed equivalent (undirected) as in the case of many mainstream Graph Theory (GT) models.

  14. Striking a Balance between Program Requirements and GT Principles: Writing a compromised GT proposal

    Directory of Open Access Journals (Sweden)

    Sherry L. Xie, Ph.D. Candidate

    2009-06-01

    Full Text Available Glaser’s term “compromised GT proposal” (2001, p.114 refers to the type of Grounded Theory (GT proposal that is written in order to conform to the requirements of a standardized qualitative research proposal. A GT proposal needs only to supply information on the area of interest, the data source and a statement of method to the effect that the researcher begin to collect, code and analyse the data and let the theory emerge. Thus, the proposal may only occupy “a page or two” (Glaser, 2001, p. 111. Whilst being consistent with the methodology, a GT proposal sometimes has to give way to the format specified by a PhD program or committee even though the format was not defined for a GT proposal and in some areas, conflicts with GT principles; for example, the format may require a literature review. This short paper reports on my experience of writing a compromised GT proposal as a first-time GT researcher. It describes how both Glaser’s advice on writing compromised GT research proposals and the characteristics of the substantive area of the proposed research were used to satisfy program requirements while still maintaining GT fundamentals.

  15. Quantum perfect correlations

    International Nuclear Information System (INIS)

    Ozawa, Masanao

    2006-01-01

    The notion of perfect correlations between arbitrary observables, or more generally arbitrary POVMs, is introduced in the standard formulation of quantum mechanics, and characterized by several well-established statistical conditions. The transitivity of perfect correlations is proved to generally hold, and applied to a simple articulation for the failure of Hardy's nonlocality proof for maximally entangled states. The notion of perfect correlations between observables and POVMs is used for defining the notion of a precise measurement of a given observable in a given state. A longstanding misconception on the correlation made by the measuring interaction is resolved in the light of the new theory of quantum perfect correlations

  16. PERFECT DEMAND ILLUSION

    Directory of Open Access Journals (Sweden)

    Alexander Yu. Sulimov

    2015-01-01

    Full Text Available The article is devoted to technique «Perfect demand illusion», which allows to strengthen the competitive advantageof retailers. Also in the paper spells out the golden rules of visual merchandising.The definition of the method «Demand illusion», formulated the conditions of its functioning, and is determined by the mainhypothesis of the existence of this method.Furthermore, given the definition of the «Perfect demand illusion», and describes its additional conditions. Also spells out the advantages of the «Perfect demandillusion», before the «Demand illusion».

  17. Detection of non-ΔGT NCF-1 mutations in chronic granulomatous disease

    DEFF Research Database (Denmark)

    Jakobsen, Marianne Antonius; Pedersen, Svend Stenvang; Barington, Torben

    2009-01-01

    to have mutations in NCF-1 encoding p47-phox, which is part of the cytosolic component of NADPH oxidase. More than 94% of these patients share the same mutation, a 2 bp GT deletion in the GTGT dinucleotide repeat in the start of exon 2. The presence of two pseudogenes more than 98% homologous...

  18. Presentation summary: Gas Turbine - Modular Helium Reactor (GT-MHR)

    International Nuclear Information System (INIS)

    2001-01-01

    Numerous prototypes and demonstration plants have been constructed and operated beginning with the Dragon plant in the early 1960s. The MHTGR was the U.S. developed modular plant and underwent pre application review by NRC. The GT-MHR represents a further refinement on this concept with the steam cycle being replaced by a closed loop gas turbine (Brayton) cycle. Modular gas reactors and the GT-MHR represent a fundamental shift in reactor design and safety philosophy. The reactor system is contained in a 3 vessel, side-by-side arrangement. The reactor and a shutdown cooling system are in one vessel, and the gas turbine based power conversion system, including the generator, in a second parallel vessel. A more detailed look at the system shows the compact arrangement of gas turbine, compressors, recuperator, heat exchanges, and generator. Fueled blocks are stacked in three concentric rings with inert graphite blocks making up the inner and outer reflectors. Operating control rods are located outside the active core while startup control rods and channels for reserve shutdown pellets are located near the core center. Ceramic coated fuel is the key to the GT-MHR's safety and economics. A kernel of Uranium oxycarbide (or UO 2 ) is placed in a porous carbon buffer and then encapsulated in multiple layers of pyrolytic carbon and silicon carbide. These micro pressure vessels withstand internal pressures of up to 2,000 psi and temperatures of nearly 2,000 C providing extremely resilient containment of fission products under both normal operating and accident conditions. The fuel particles are blended in carbon pitch, forming fuel rods, and then loaded into holes within large graphite fuel elements. Fuel elements are stacked to form the core. Fuel particle testing in has repeatedly demonstrated the high temperature resilience of coated particle fuel to temperature approaching 2,000 C. As an conservative design goal, GT-MHR has been sized to keep maximum fuel temperatures

  19. Tests of Hadronic Probes of GT Strength

    CERN Multimedia

    2002-01-01

    There are many important problems where one wishes to know the distribution of Gamow-Teller (GT) strength in circumstances where it cannot be measured directly (for example, because of energy-release limitations). Then one must rely on hadronic probes to infer the GT strength. It is therefore essential to test these probes as extensively as possible. The isospin-analog transitions in $^{37}$Ca $\\beta^{+}$ -decay and $^{37}$Cl$(p, n)$ provide an excellent ground for such a test. Recent $^{37}$Cl$ (p, n) $ studies, while qualitatively in agreement with our previous ISOLDE work on $^{37}$Ca $\\beta^{+} $ -decay, show quantitative discrepancies that appear to grow as the excitation energy in the residual nuclei increases. Because of the bulk of the GT strengh appears at these high excitation energies, it is important to extend the $\\beta$-decay data to even higher excitation energies where, because of rapidly diminishing phase-space, strong GT transitions correspond to very weak $\\beta$ -branches. We propose to do...

  20. GT-MHR design, performance, and safety

    International Nuclear Information System (INIS)

    Neylan, A.J.; Shenoy, A.; Silady, F.A.; Dunn, T.D.

    1994-11-01

    The Gas Turbine-Modular Helium Reactor (GT-MHR) is the result of coupling the evolution of a low power density passively safe modular reactor with key technology developments in the U.S. during the last decade: large industrial gas turbines; large active magnetic bearings; and compact, highly effective plate-fin heat exchangers. This is accomplished through the unique use of the Brayton cycle to produce electricity with the helium as primary coolant from the reactor directly driving the gas turbine electrical generator. This cycle can achieve a high net efficiency in the range of 45% to 48%. In the design of the GT-MHR the desirable inherent characteristics of the inert helium coolant, graphite core, and the coated fuel particles are supplemented with specific design features such as passive heat removal to achieve the safety objective of not disturbing the normal day-to-day activities of the public even for beyond design basis rare accidents. Each GT-MHR plant consists of four modules. The GT-MHR module components are contained within steel pressure vessels: a reactor vessel, a power conversion vessel, and a connecting cross vessel. All vessels are sited underground in a concrete silo, which serves as an independent vented low pressure containment structure. By capitalizing on industrial and aerospace gas turbine development, highly effective heat exchanger designs, and inherent gas cooled reactor temperature characteristics, the passively safe GT-MHR provides a sound technical, monetary, and environmental basis for new nuclear power generating capacity. This paper provides an update on the status of the design, which has been under development on the US-DOE program since February 1993. An assessment of plant performance and safety is also included

  1. HTR-10GT AMBs displacement sensor design

    International Nuclear Information System (INIS)

    Shi Zhengang; Zha Meisheng; Zhao Lei; Sun Zhuo

    2005-01-01

    The 10 MW high temperature gas-cooled test module reactor (HTR-10GT) with the core made of spherical fuel elements was designed and constructed by the Institute of Nuclear and New Energy Technology of Tsinghua University in China. In the HTR-10GT, turbo-compressor and generator rotors are connected by a flexible coupling. The rotors, restricted by actual instruments and working environment, must be supported without any contact and lubrication. Active magnetic bearing (AMB), known as its advantages over the conventional bearings., such as contact-free, no-lubricating and active damping vibration, is the best way to suspend and stabilize the position of rotors of HTR-10GT. Each rotor is suspended by two radial and one axial AMBs. The radial AMB's radial gap is 0.15 mm considering the gap of 0.4 mm between the compressor stator and blades in order to protect the compressor. The control system controls the rotor position to meet the required gaps between rotor and stator through windings current. All the position information concerning radial and axial AMB is generated by sensors for measuring the displacement of the levitated body. Some typical sensors, i.e. eddy current displacement sensor, capacitive displacement sensor, can provide position information, but, quite often, unsatisfactory anti-jamming, which is a key issue for AMB systems near generator and other electric devices in HTR-10GT. Therefore, a kind of new type sensor is designed to measure the radial and axial displacements and the vibration of the rotors. This paper focuses on the design characteristics of the HTR-10GT AMBs displacement sensors and introduction of the related experiments to demonstrate its performance. (authors)

  2. Everybody's Different Nobody's Perfect

    Science.gov (United States)

    ... traten ni qué edad tengan — eso se llama “DISCAPACIDAD.” Some kids have a disability because their muscles ... have one? ¿Conoces a alguien que tenga una discapacidad? ¿Tienes una tú? Everybody’s different, nobody’s perfect. So ...

  3. California's Perfect Storm

    Science.gov (United States)

    Bacon, David

    2010-01-01

    The United States today faces an economic crisis worse than any since the Great Depression of the 1930s. Nowhere is it sharper than in the nation's schools. Last year, California saw a perfect storm of protest in virtually every part of its education system. K-12 teachers built coalitions with parents and students to fight for their jobs and their…

  4. The Perfect Text.

    Science.gov (United States)

    Russo, Ruth

    1998-01-01

    A chemistry teacher describes the elements of the ideal chemistry textbook. The perfect text is focused and helps students draw a coherent whole out of the myriad fragments of information and interpretation. The text would show chemistry as the central science necessary for understanding other sciences and would also root chemistry firmly in the…

  5. Selection of JAERI'S HTGR-GT concept

    International Nuclear Information System (INIS)

    Muto, Y.; Ishiyama, S.; Shiozawa, S.

    2001-01-01

    In JAERI, a feasibility study of HTGR-GT has been conducted as an assigned work from STA in Japan since January 1996. So far, the conceptual or preliminary designs of 600, 400 and 300 MW(t) power plants have been completed. The block type core and pebble-bed core have been selected in 600 MW(t) and 400/300 MW(t), respectively. The gas-turbine system adopts a horizontal single shaft rotor and then the power conversion vessel is separated into a turbine vessel and a heat exchanger vessel. In this paper, the issues related to the selection of these concepts are technically discussed. (author)

  6. Building the perfect PC

    CERN Document Server

    Thompson, Robert Bruce

    2006-01-01

    This popular Build-It-Yourself (BIY) PC book covers everything you want to know about building your own system: Planning and picking out the right components, step-by-step instructions for assembling your perfect PC, and an insightful discussion of why you'd want to do it in the first place. Most big brand computers from HP, Dell and others use lower-quality components so they can meet their aggressive pricing targets. But component manufacturers also make high-quality parts that you can either purchase directly, or obtain through distributors and resellers. Consumers and corporations

  7. Perfect imaging without negative refraction

    OpenAIRE

    Leonhardt, Ulf

    2009-01-01

    Perfect imaging has been believed to rely on negative refraction, but here we show that an ordinary positively-refracting optical medium may form perfect images as well. In particular, we establish a mathematical proof that Maxwell's fish eye in two-dimensional integrated optics makes a perfect instrument with a resolution not limited by the wavelength of light. We also show how to modify the fish eye such that perfect imaging devices can be made in practice. Our method of perfect focusing ma...

  8. Perfect imaging without negative refraction

    Energy Technology Data Exchange (ETDEWEB)

    Leonhardt, Ulf [School of Physics and Astronomy, University of St Andrews, North Haugh, St Andrews KY16 9SS (United Kingdom)], E-mail: ulf@st-andrews.ac.uk

    2009-09-15

    Perfect imaging has been believed to rely on negative refraction, but here we show that an ordinary positively refracting optical medium may form perfect images as well. In particular, we establish a mathematical proof that Maxwell's fish eye in two-dimensional (2D) integrated optics makes a perfect instrument with a resolution not limited by the wavelength of light. We also show how to modify the fish eye such that perfect imaging devices can be made in practice. Our method of perfect focusing may also find applications outside of optics, in acoustics, fluid mechanics or quantum physics, wherever waves obey the 2D Helmholtz equation.

  9. Perfect and imperfect states

    Directory of Open Access Journals (Sweden)

    Nikitović Aleksandar

    2013-01-01

    Full Text Available Early Greek ethics embodied in Cretan and Spartan mores, served as a model for Plato`s political theory. Plato theorized the contents of early Greek ethics, aspiring to justify and revitalize the fundamental principles of a traditional view of the world. However, according to Plato`s new insight, deed is further from the truth than a thought i.e. theory. The dorian model had to renounce its position to the perfect prototype of a righteous state, which is a result of the inner logic of philosophical theorizing in early Greek ethics. Prototype and model of philosophical reflection, in comparison to philosophical theory, becomes minor and deficient. Philosophical theorizing of early Greek ethics philosophically formatted Greek heritage, initiating substantial changes to the content of traditional ethics. Replacement of the myth with ontology, as a new foundation of politics, transformed early Greek ethics in various relevant ways. [Projekat Ministarstva nauke Republike Srbije, br. 179049

  10. Perfect pitch reconsidered.

    Science.gov (United States)

    Moulton, Calum

    2014-10-01

    Perfect pitch, or absolute pitch (AP), is defined as the ability to identify or produce the pitch of a sound without need for a reference pitch, and is generally regarded as a valuable asset to the musician. However, there has been no recent review of the literature examining its aetiology and its utility taking into account emerging scientific advances in AP research, notably in functional imaging. This review analyses the key empirical research on AP, focusing on genetic and neuroimaging studies. The review concludes that: AP probably has a genetic predisposition, although this is based on limited evidence; early musical training is almost certainly essential for AP acquisition; and, although there is evidence that it may be relevant to speech processing, AP can interfere with relative pitch, an ability on which humans rely to communicate effectively. The review calls into question the value of AP to musicians and non-musicians alike. © 2014 Royal College of Physicians.

  11. Metamaterials for perfect absorption

    CERN Document Server

    Lee, Young Pak; Yoo, Young Joon; Kim, Ki Won

    2016-01-01

    This book provides a comprehensive overview of the theory and practical development of metamaterial-based perfect absorbers (MMPAs). It begins with a brief history of MMPAs which reviews the various theoretical and experimental milestones in their development. The theoretical background and fundamental working principles of MMPAs are then discussed, providing the necessary background on how MMPAs work and are constructed. There then follows a section describing how different MMPAs are designed and built according to the operating frequency of the electromagnetic wave, and how their behavior is changed. Methods of fabricating and characterizing MMPAs are then presented. The book elaborates on the performance and characteristics of MMPAs, including electromagnetically-induced transparency (EIT). It also covers recent advances in MMPAs and their applications, including multi-band, broadband, tunability, polarization independence and incidence independence. Suitable for graduate students in optical sciences and e...

  12. Perfect simulation of Hawkes processes

    DEFF Research Database (Denmark)

    Møller, Jesper; Rasmussen, Jakob Gulddahl

    This article concerns a perfect simulation algorithm for unmarked and marked Hawkes processes. The usual stratihtforward simulation algorithm suffers from edge effects, whereas our perfect simulation algorithm does not. By viewing Hawkes processes as Poisson cluster processes and using...... their branching and conditional independence structure, useful approximations of the distribution function for the length of a cluster are derived. This is used to construct upper and lower processes for the perfect simulation algorithm. Examples of applications and empirical results are presented....

  13. Perfect simulation of Hawkes processes

    DEFF Research Database (Denmark)

    Møller, Jesper; Rasmussen, Jakob Gulddahl

    2005-01-01

    Our objective is to construct a perfect simulation algorithm for unmarked and marked Hawkes processes. The usual straightforward simulation algorithm suffers from edge effects, whereas our perfect simulation algorithm does not. By viewing Hawkes processes as Poisson cluster processes and using...... their branching and conditional independence structures, useful approximations of the distribution function for the length of a cluster are derived. This is used to construct upper and lower processes for the perfect simulation algorithm. A tail-lightness condition turns out to be of importance...... for the applicability of the perfect simulation algorithm. Examples of applications and empirical results are presented....

  14. A comparison of the Actigraph GT1M and GT3X accelerometers under standardized and free-living conditions

    International Nuclear Information System (INIS)

    Kaminsky, Leonard A; Ozemek, Cemal

    2012-01-01

    Prior to 2008, data collection from Actigraph accelerometers was only possible in the uniaxial mode. In 2009, Actigraph released the GT3X, which allows triaxial data collection. The purpose of this study was to determine if data collected by the GT3X in the uniaxial mode are comparable to its predecessor, the GT1M, under both standardized and free-living conditions. Thirty-four subjects (17 women and 17 men) provided complete data for this study. Subjects wore the accelerometers (one GT1M and one GT3X) on their waistband in line with the right and left anterior axillary lines. Each subject walked on a treadmill at speeds of 2.4, 3.2, 4.0, 4.8, 5.6 and 6.4 km h −1 for 5 min each, and then continued to wear both accelerometers for all waking hours for three consecutive days. Mean steady-state activity counts min –1 for both accelerometers were not statistically different for the standardized treadmill walking speeds and for mean minutes/day and activity counts/day for intensity classifications under the free-living condition. Based on comparisons made from both standardized walking speeds and free-living conditions, it is reasonable to compare data derived from either the GT1M or GT3X when collected in the uniaxial mode. (paper)

  15. Perfect secure domination in graphs

    Directory of Open Access Journals (Sweden)

    S.V. Divya Rashmi

    2017-07-01

    Full Text Available Let $G=(V,E$ be a graph. A subset $S$ of $V$ is a dominating set of $G$ if every vertex in $Vsetminus  S$ is adjacent to a vertex in $S.$ A dominating set $S$ is called a secure dominating set if for each $vin Vsetminus S$ there exists $uin S$ such that $v$ is adjacent to $u$ and $S_1=(Ssetminus{u}cup {v}$ is a dominating set. If further the vertex $uin S$ is unique, then $S$ is called a perfect secure dominating set. The minimum cardinality of a perfect secure dominating set of $G$ is called the perfect  secure domination number of $G$ and is denoted by $gamma_{ps}(G.$ In this paper we initiate a study of this parameter and present several basic results.

  16. International project GT-MHR - New generation of nuclear reactors

    International Nuclear Information System (INIS)

    Vasyaev, A.; Kodochigov, N.; Kuzavkov, N.; Kuznetsov, L.

    2001-01-01

    Gas turbine-modular helium reactor (GT-MHR) is the reactor of new generation, which satisfies the requirements of the progressing large-scale nuclear power engineering. The activities in GT-MHR Project started in 1995. In 1997 the Conceptual Design was developed under four-side Agreement (MINATOM, General Atomics, FRAMATOME, Fuji Electric); it has passed through the internal and international reviews, has been approved and recommended for further development as one of new trends in creation of new generation plants. Starting from 1999, the activities in the development of the Preliminary Design of the plant were deployed under the Agreement between the Government of the United States of America and the Government of the Russian Federation on Scientific and Technical Cooperation in the Management of Plutonium That Has Been Withdrawn From Nuclear Military Programs dated July 24, 1998. The activities are established under the Contract between MINATOM and OKBM Russia, and under the General Agreement between Department of Energy (DOE), USA and OKBM. The GT-MHR Project is included into 'Development Strategy of Russian Nuclear Power in the first Half of the XXI-st Century' providing for 'the participation in an international project on the development and construction of GT-MHR nuclear power plant till year 2010 and 'operation of GT-MHR prototype unit and creation of fuel fabrication facility (within framework of International Project) till year 2030'. (author)

  17. Summarized report of geothermal well Gross Buchholz Gt1; Kurzprofil der Geothermiebohrung Gross Buchholz Gt1

    Energy Technology Data Exchange (ETDEWEB)

    Schaefer, Frauke; Hesshaus, Annalena; Jatho, Reiner; Luppold, Friedrich-Wilhelm; Pletsch, Thomas; Tischner, Torsten [Bundesanstalt fuer Geowissenschaften und Rohstoffe (BGR), Hannover (Germany); Hunze, Sabine; Orilski, Judith; Wonik, Thomas [Leibniz-Institut fuer Angewandte Geophysik (LIAG), Hannover (Germany); Roehling, Heinz-Gerd [Landesamt fuer Bergbau, Energie und Geologie (LBEG), Hannover (Germany)

    2012-01-15

    The well Gross Buchholz Gt1 is a deep geothermal well intended to demonstrate the feasibility of deep geothermal energy mining from tight sedimentary rocks. It is the core part of the GeneSys (Generated Geothermal Energy Systems) project, aiming at developing single well concepts for direct use of geothermal energy. During the course of the project, three different single well concepts have been developed and tested at the research well Horstberg Z1 which is geologically comparable to the Gross Buchholzwell. The latter is intended to supply the heating energy for the premises of Geozentrum Hannover, an office and lab complex of some 35.000 m{sup 2} housing about 1000 employees. The geothermal target are the sandstones of the Lower Triassic Middle Buntsandstein Formation, which have a temperature of about 165 C at 3700 depth. The well has reached a final depth of 3901 m below ground level, penetrating a nearly complete succession from the Lower Cretaceous (Albian) to the Lower Triassic (Lower Buntsandstein), while Tertiary and Upper Cretaceous sediments are missing. This article summarizes technical and geographic data, stratigraphic classification, geophysical logging, cores, and sidewall cores of the well. (orig.)

  18. HTGR-GT and electrical load integrated control

    International Nuclear Information System (INIS)

    Chan, T.; Openshaw, F.; Pfremmer, D.

    1980-05-01

    A discussion of the control and operation of the HTGR-GT power plant is presented in terms of its closely coupled electrical load and core cooling functions. The system and its controls are briefly described and comparisons are made with more conventional plants. The results of analyses of selected transients are presented to illustrate the operation and control of the HTGR-GT. The events presented were specifically chosen to show the controllability of the plant and to highlight some of the unique characteristics inherent in this multiloop closed-cycle plant

  19. Life cycle assessment of an SOFC/GT process

    Energy Technology Data Exchange (ETDEWEB)

    Olausson, Pernilla

    1999-06-01

    For the last few years much effort has been put into the research on different kinds of fuel cells, since these are considered to be both an efficient and environment friendly way to convert energy. The fuel cell studied here is the solid oxide fuel cell (SOFC) that works at a high temperature (800-1000 C) and today achieves a stand-alone electric efficiency of approximately 50%. When integrating the SOFC in a gas turbine process (SOFC/GT process) an efficiency of 70-75% can be reached. The SOFC and the SOFC/GT process are considered to be environment friendly regarding the discharges during operation. Especially formation of nitrogen oxides (NO{sub x}) is low since the SOFC temperatures are low compared to NO{sub x} formation temperatures. To study the whole environmental impact of the SOFC/GT process a life cycle assessment (LCA) is carried out to find the `hot spots` in the process` life cycle. Since the SOFC/GT process is under development today the collected data are mainly from literature and articles based on laboratory results. When performing the LCA only the SOFC-module and the gas turbine are included. A collection of data of all processes included, extraction of minerals, processing of raw material, production of the components, operation of the SOFC/GT process and transports between all these processes. These data are then added up and weighted in impact categories to evaluate the total environmental impact of the SOFC/GT process. All these steps are performed according to the ISO 14040-series. The stand-alone most contributing phase during the life cycle of the SOFC/GT process was found to be the production of the SOFC. All processes during the production of the SOFC are carried out under laboratory circumstances, which require more energy and materials than if the processes were commercialised and optimised. For the SOFC/GT process to be competitive with other energy converting processes regarding the discharges of emissions to the air, the use of

  20. Perfect sequences over the real quaternions

    OpenAIRE

    Kuznetsov, Oleg

    2017-01-01

    In this Thesis, perfect sequences over the real quaternions are first considered. Definitions for the right and left periodic autocorrelation functions are given, and right and left perfect sequences introduced. It is shown that the right (left) perfection of any sequence implies the left (right) perfection, so concepts of right and left perfect sequences over the real quaternions are equivalent. Unitary transformations of the quaternion space ℍ are then considered. Using the equivalence of t...

  1. Ground reaction force estimates from ActiGraph GT3X+ hip accelerations.

    Directory of Open Access Journals (Sweden)

    Jennifer M Neugebauer

    Full Text Available Simple methods to quantify ground reaction forces (GRFs outside a laboratory setting are needed to understand daily loading sustained by the body. Here, we present methods to estimate peak vertical GRF (pGRFvert and peak braking GRF (pGRFbrake in adults using raw hip activity monitor (AM acceleration data. The purpose of this study was to develop a statistically based model to estimate pGRFvert and pGRFbrake during walking and running from ActiGraph GT3X+ AM acceleration data. 19 males and 20 females (age 21.2 ± 1.3 years, height 1.73 ± 0.12 m, mass 67.6 ± 11.5 kg wore an ActiGraph GT3X+ AM over their right hip. Six walking and six running trials (0.95-2.19 and 2.20-4.10 m/s, respectively were completed. Average of the peak vertical and anterior/posterior AM acceleration (ACCvert and ACCbrake, respectively and pGRFvert and pGRFbrake during the stance phase of gait were determined. Thirty randomly selected subjects served as the training dataset to develop generalized equations to predict pGRFvert and pGRFbrake. Using a holdout approach, the remaining 9 subjects were used to test the accuracy of the models. Generalized equations to predict pGRFvert and pGRFbrake included ACCvert and ACCbrake, respectively, mass, type of locomotion (walk or run, and type of locomotion acceleration interaction. The average absolute percent differences between actual and predicted pGRFvert and pGRFbrake were 8.3% and 17.8%, respectively, when the models were applied to the test dataset. Repeated measures generalized regression equations were developed to predict pGRFvert and pGRFbrake from ActiGraph GT3X+ AM acceleration for young adults walking and running. These equations provide a means to estimate GRFs without a force plate.

  2. WS-VLAM: A GT4 based workflow management system

    NARCIS (Netherlands)

    Wibisono, A.; Vasyunin, D.; Korkhov, V.; Zhao, Z.; Belloum, A.; de Laat, C.; Adriaans, P.; Hertzberger, B.

    2007-01-01

    Generic Grid middleware, e.g., Globus Toolkit 4 (GT4), provides basic services for scientific workflow management systems to discover, store and integrate workflow components. Using the state of the art Grid services can advance the functionality of workflow engine in orchestrating distributed Grid

  3. Adiponectin Single Nucleotide Polymorphism (+276G/T) and Its ...

    African Journals Online (AJOL)

    The present study was investigating the association between the single nucleotide polymorphism +276 G/T of the adiponectin gene with serum adiponectin level in patients with coronary artery disease (CAD). In this study 100 healthy controls and 100 Egyptian patients with coronary artery disease of both genders ...

  4. Perfect quantum multiple-unicast network coding protocol

    Science.gov (United States)

    Li, Dan-Dan; Gao, Fei; Qin, Su-Juan; Wen, Qiao-Yan

    2018-01-01

    In order to realize long-distance and large-scale quantum communication, it is natural to utilize quantum repeater. For a general quantum multiple-unicast network, it is still puzzling how to complete communication tasks perfectly with less resources such as registers. In this paper, we solve this problem. By applying quantum repeaters to multiple-unicast communication problem, we give encoding-decoding schemes for source nodes, internal ones and target ones, respectively. Source-target nodes share EPR pairs by using our encoding-decoding schemes over quantum multiple-unicast network. Furthermore, quantum communication can be accomplished perfectly via teleportation. Compared with existed schemes, our schemes can reduce resource consumption and realize long-distance transmission of quantum information.

  5. Visible light broadband perfect absorbers

    Energy Technology Data Exchange (ETDEWEB)

    Jia, X. L.; Meng, Q. X.; Yuan, C. X.; Zhou, Z. X.; Wang, X. O., E-mail: wxo@hit.edu.cn [School of Science, Harbin Institute of Technology, Harbin 150001 (China)

    2016-03-15

    The visible light broadband perfect absorbers based on the silver (Ag) nano elliptical disks and holes array are studied using finite difference time domain simulations. The semiconducting indium silicon dioxide thin film is introduced as the space layer in this sandwiched structure. Utilizing the asymmetrical geometry of the structures, polarization sensitivity for transverse electric wave (TE)/transverse magnetic wave (TM) and left circular polarization wave (LCP)/right circular polarization wave (RCP) of the broadband absorption are gained. The absorbers with Ag nano disks and holes array show several peaks absorbance of 100% by numerical simulation. These simple and flexible perfect absorbers are particularly desirable for various potential applications including the solar energy absorber.

  6. Perfect Liberty or Natural Liberty?

    DEFF Research Database (Denmark)

    Jacobsen, Stefan Gaarsmand

    2012-01-01

    The article investigates the concept of natural order as it is used by François Quesnay and Adam Smith in their respective economic writings. While Smith used the concept only after having visited Quesnay and the Physiocrats in France in the 1760s, in The Wealth of Nations he sought to negotiate...... the meaning of what was “natural” about economic life. The Physiocrats believed it possible to identify a model or a perfect regime of natural order – an order that they in fact thought to exist and function in China due to a rigorous system of economic laws. Smith sided with contemporary critics...... of this metaphysical vision of economic perfection (and of Chinese governance), but he suggested that the economic mechanisms of the physiocratic theories would remain intact even with a minimum of control by state laws. However, Smith’s balancing act on these questions remained disputed even by his Scottish...

  7. Looking beyond the perfect lens

    International Nuclear Information System (INIS)

    Wee, W H; Pendry, J B

    2010-01-01

    The holy grail of imaging is the ability to see through anything. From the conservation of energy, we can easily see that to see through a lossy material would require lenses with gain. The aim of this paper therefore is to propose a simple scheme by which we can construct a general perfect lens, with gain-one that can restore both the phases and amplitudes of near and far fields.

  8. Critical phenomena at perfect and non-perfect surfaces

    International Nuclear Information System (INIS)

    Pleimling, M

    2004-01-01

    In the past, perfect surfaces have been shown to yield local critical behaviour that differs from bulk critical behaviour. On the other hand, surface defects, whether they are of natural origin or created artificially, are known to modify local quantities. It is therefore important to clarify whether these defects are relevant or irrelevant for the surface critical behaviour. The purpose of this review is two-fold. In the first part we summarize some of the important results on surface criticality at perfect surfaces. Special attention is thereby paid to new developments such as for example the study of the surface critical behaviour in systems with competing interactions or of surface critical dynamics. In the second part the effect of surface defects (presence of edges, steps, quenched randomness, lines of adatoms, regular geometric patterns) on local critical behaviour in semi-infinite systems and in thin films is discussed in detail. Whereas most of the defects commonly encountered are shown to be irrelevant, some notable exceptions are highlighted. It is shown furthermore that under certain circumstances non-universal local critical behaviour may be observed at surfaces. (topical review)

  9. Generating perfect fluid spheres in general relativity

    Science.gov (United States)

    Boonserm, Petarpa; Visser, Matt; Weinfurtner, Silke

    2005-06-01

    Ever since Karl Schwarzschild’s 1916 discovery of the spacetime geometry describing the interior of a particular idealized general relativistic star—a static spherically symmetric blob of fluid with position-independent density—the general relativity community has continued to devote considerable time and energy to understanding the general-relativistic static perfect fluid sphere. Over the last 90 years a tangle of specific perfect fluid spheres has been discovered, with most of these specific examples seemingly independent from each other. To bring some order to this collection, in this article we develop several new transformation theorems that map perfect fluid spheres into perfect fluid spheres. These transformation theorems sometimes lead to unexpected connections between previously known perfect fluid spheres, sometimes lead to new previously unknown perfect fluid spheres, and in general can be used to develop a systematic way of classifying the set of all perfect fluid spheres.

  10. Generating perfect fluid spheres in general relativity

    International Nuclear Information System (INIS)

    Boonserm, Petarpa; Visser, Matt; Weinfurtner, Silke

    2005-01-01

    Ever since Karl Schwarzschild's 1916 discovery of the spacetime geometry describing the interior of a particular idealized general relativistic star--a static spherically symmetric blob of fluid with position-independent density--the general relativity community has continued to devote considerable time and energy to understanding the general-relativistic static perfect fluid sphere. Over the last 90 years a tangle of specific perfect fluid spheres has been discovered, with most of these specific examples seemingly independent from each other. To bring some order to this collection, in this article we develop several new transformation theorems that map perfect fluid spheres into perfect fluid spheres. These transformation theorems sometimes lead to unexpected connections between previously known perfect fluid spheres, sometimes lead to new previously unknown perfect fluid spheres, and in general can be used to develop a systematic way of classifying the set of all perfect fluid spheres

  11. Deployment Repeatability

    Science.gov (United States)

    2016-04-01

    evaluating the deployment repeatability builds upon the testing or analysis of deployment kinematics (Chapter 6) and adds repetition. Introduction...material yield or failure during a test. For the purposes of this chapter, zero shift will refer to permanent changes in the structure, while reversible ...the content of other chapters in this book: Gravity Compensation (Chapter 4) and Deployment Kinematics and Dynamics (Chapter 6). Repeating the

  12. Breast milk is conditionally perfect.

    Science.gov (United States)

    Erick, Miriam

    2018-02-01

    Breast milk is the universal preferred nutrition for the newborn human infant. New mother have been encouraged to exclusively breastfeed by health care professionals and consumer-advocacy forums for years, citing "breast milk is the perfect food". The benefits are numerous and include psychological, convenience, economical, ecological and nutritionally superior. Human milk is a composite of nutritional choices of the mother, commencing in the pre-conceptual era. Events influencing the eventual nutritional profile of breast milk for the neonate start with pre-conceptual dietary habits through pregnancy and finally to postpartum. Food choices do affect the nutritional profile of human breast milk. It is not known who coined the phrase "breast milk is the perfect food" but it is widely prevalent in the literature. While breast milk is highly nutritive, containing important immunological and growth factors, scientific investigation reveals a few short-falls. Overall, human breast milk has been found to be low in certain nutrients in developed countries: vitamin D, iodine, iron, and vitamin K. Additional nutrient deficiencies have been documented in resource-poor countries: vitamin A, vitamin B 12, zinc, and vitamin B 1/thiamin. Given these findings, isn't it more accurate to describe breast milk as "conditionally perfect"? Correcting the impression that breast milk is an inherently, automatically comprehensive enriched product would encourage women who plan to breastfeed an opportunity to concentrate on dietary improvement to optimizes nutrient benefits ultimately to the neonate. The more immediate result would improve pre-conceptual nutritional status. Here, we explore the nutritional status of groups of young women; some of whom will become pregnant and eventually produce breast milk. We will review the available literature profiling vitamin, mineral, protein and caloric content of breast milk. We highlight pre-existing situations needing correction to optimize

  13. Thermal cycle efficiency of the indirect combined HTGR-GT power generation system

    Energy Technology Data Exchange (ETDEWEB)

    Muto, Yasushi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1996-02-01

    High thermal efficiency of 50% could be expected in a power generation system coupling a high temperature gas-cooled reactor(HTGR) with a closed cycle gas turbine(GT). There are three candidate systems such as a direct cycle(DC), an indirect cycle(ICD) and an indirect combined cycle(IDCC). The IDCC could solve many problems in both the DC and the IDC and consists of a primary circuit and a secondary circuit where a topping cycle is a Brayton cycle and a bottoming cycle is a steam cycle. In this report, the thermal cycle efficiency of the IDCC is examined regarding configurations of components and steam pressure. It has been shown that there are two types of configurations, that is, a perfect cascade type and a semi-cascade one and the latter can be further classified into Case A, Case B and Case C. The conditions achieving the maximum thermal cycle efficiency were revealed for these cases. In addition, the optimum system configurations were proposed considering the thermal cycle efficiency, safety and plant arrangement. (author).

  14. The pursuit of perfect packing

    CERN Document Server

    Weaire, Denis

    2008-01-01

    Coauthored by one of the creators of the most efficient space packing solution, the Weaire-Phelan structure, The Pursuit of Perfect Packing, Second Edition explores a problem of importance in physics, mathematics, chemistry, biology, and engineering: the packing of structures. Maintaining its mathematical core, this edition continues and revises some of the stories from its predecessor while adding several new examples and applications. The book focuses on both scientific and everyday problems ranging from atoms to honeycombs. It describes packing models, such as the Kepler conjecture, Voronoï decomposition, and Delaunay decomposition, as well as actual structure models, such as the Kelvin cell and the Weaire-Phelan structure. The authors discuss numerous historical aspects and provide biographical details on influential contributors to the field, including emails from Thomas Hales and Ken Brakke. With examples from physics, crystallography, engineering, and biology, this accessible and whimsical bo...

  15. The pursuit of perfect packing

    CERN Document Server

    Weaire, Denis

    2000-01-01

    In 1998 Thomas Hales dramatically announced the solution of a problem that has long teased eminent mathematicians: what is the densest possible arrangement of identical spheres? The Pursuit of Perfect Packing recounts the story of this problem and many others that have to do with packing things together. The examples are taken from mathematics, physics, biology, and engineering, including the arrangement of soap bubbles in foam, atoms in a crystal, the architecture of the bee''s honeycomb, and the structure of the Giant''s Causeway. Using an informal style and with key references, the book also includes brief accounts of the lives of many of the scientists who devoted themselves to problems of packing over many centuries, together with wry comments on their efforts. It is an entertaining introduction to the field for both specialists and the more general public.

  16. International co-operation in developing the GT-MHR

    International Nuclear Information System (INIS)

    La Bar, M.P.; Simon, W.A.

    1997-01-01

    In the Fall of 1995, driven by budget constraints and anti-nuclear sentiments, the US government decided to discontinue financial support of the Gas Turbine-Modular Helium Reactor (GT-MHR). At that time, significant work was underway with participation of several vendors with specialized expertise in various aspects of the GT-MHR. Fortunately the US government provided for documenting the design and development status through an orderly close-out program. Concurrent elimination of government restrictions opened the door for broader international cooperation. Discussion between General Atomics and the Russian Ministry of Atomic Energy (MINATOM), in the summer of 1994, led to an agreement on a jointly funded design and development program for the GT-MHR. The program is initially focused on the burning of weapons plutonium that becomes available from dismantled nuclear weapons. The long term goal is to utilize the same design for commercial applications - using uranium fuel. This program took advantage of existing technologies and facilities in the US and Russia, but right from the beginning left the door open for broader international cooperation. Accordingly, in January 1996, FRAMATOME has joined the ongoing effort. Discussions are underway with other international entities to join this program. The program is proceeding well. Several Russian laboratories/design organizations are participating with GA and FRAMATOME. Significant improvements in the power conversion system design are a clear example of the benefit of the cooperative effort. Further work needs to be done to confirm fuel and components prior to full deployment, etc., providing ample opportunities for international cooperation in many areas

  17. Turbo-machine deployment of HTR-10 GT

    International Nuclear Information System (INIS)

    Zhu Shutang; Wang Jie; Zhang Zhengming; Yu Suyuan

    2005-01-01

    As a testing project of gas turbine modular High Temperature Gas-cooled Reactor (HTGR), HTR-10GT has been studied and developed by Institute of Nuclear and New Energy Technology (INET) of Tsinghua University after the success of HTR-10 with steam turbine cycle. The main purposes of this project are to demonstrate the gas turbine modular HTGR, to optimize the deployment of Power Conversion Unit (PCU) and to verify the techniques of turbo-machine, operating modes and controlling measures. HTR-10GT is concentrated on the PCU design and the turbo-machine deployment. Possible turbo-machine deployments have been investigated and two of them are introduced in this paper. The preliminary design for the turbo-machine of HTR-10GT is single-shaft of vertical layout, arranged by the side of the reactor and the turbo-compressor rotary speed was selected to be 250 s -1 (15000 r/min) by considering the efficiency of turbo-compressor blade systems, the strength conditions and the mass and size characteristics of the turbo-compressor. The rotor system will be supported by electromagnetic bearings (EMBs) to curb the possible pollutions of the primary loop. Of all the components in this design, the high speed turbo-generator seems to be a world-wide technical nut. As an alternative design, a gearbox complex is used to reduce the rotary speed from the turbo-compressor 250 s -1 to 50 s -1 so that the ordinary generator can be used. (authors)

  18. Uligevægt mellem familie og arbejdsliv

    DEFF Research Database (Denmark)

    Boje, Thomas P.; Ejrnæs, Anders

    2015-01-01

    Kapitlet beskriver og diskuterer de strategier, som bliver anvendt i familiepolitikken i Danmark såvel som i udvalgte europæiske lande med det formål at sikre en bedre ligevægt mellem de krav, som stilles til forældrene i arbejdslivet og i familien i form af omsorg for børn. Kapitlet afsluttes me...... beskrivelse af en familiepolitisk typologi, og hvordan relationen mellem familie og arbejde kommer til udtryk i de forskellige europæiske velfærdsregimer....

  19. Development of GT-MGR plant power conversion unit design

    International Nuclear Information System (INIS)

    Kostin, V.I.; Kodochigov, N.G.; Belov, S.E.; Vasyaev, A.V.; Golovko, V.F.; Shenoj, A.

    2007-01-01

    The General Atomic Company (USA) and the Pilot Design Bureau for Machine-Building (Russia) are involved in the efforts to design the GT-MGR modular helium cooled reactor and the energy conversion unit with the direct gas turbine cycle. The reactor capacity is equal to 600 MW, it is cooled by helium under 7 MPa pressure. The energy conversion unit consists of a gas turbine, a recuperator, preliminary and intermediate coolers, a generator. The turbine shaft rotation frequency is equal to 4400 rotation/minute. One analyzed the alternate designs of the energy conversion unit to choose its configuration [ru

  20. Obsession with perfection: Body dysmorphia.

    Science.gov (United States)

    Vashi, Neelam A

    The deeply rooted fascination with beauty penetrates society worldwide. The indulgence to look and feel beautiful pervades all ages, genders, and nationalities, with research conferring a remarkable tendency to agree on measures of attractiveness among these disparate groups. Research has found that beautiful people do, in fact, receive more desirable outcomes in life and job satisfaction, family formation, and overall happiness. Humans have a tendency to respond to attractive persons more favorably, driving many patients to our clinics. Although some dissatisfaction with one's appearance is common and normal, excessive concern with certain facial or body attributes can be sign of an underlying disorder. Body dysmorphic disorder (BDD) is a disorder of self-perception. It is the obsession with perfection. Defined as the impairing preoccupation with a nonexistent or minimal flaw in appearance, BDD affects 0.7-2.4% of the general population and a much larger percentage of those attempting to receive aesthetic treatments. Clinicians should be aware of this disorder and remain vigilant because such patients will not be satisfied with corrective procedures. Although not involving cosmetic intervention, the treatment of BDD does involve psychiatric referral and psychopharmacologic therapy, with patients receiving these having a much better prognosis. Copyright © 2016 Elsevier Inc. All rights reserved.

  1. Porsche GT3 R Hybrid. Prototype and race lab; Porsche GT3 R Hybrid. Technologietraeger und rollendes Labor

    Energy Technology Data Exchange (ETDEWEB)

    Armbruster, Daniel [Porsche Motorsport, Weissach (Germany); Hennings, Stephan [Karlsruher Institut fuer Technologie (KIT), Karlsruhe (Germany). Inst. fuer Fahrzeugsystemtechnik

    2011-05-15

    Hybrid technology is one of the key technologies for coping with changing future requirements in the area of individual mobility. This technology is already being used in small, mid-size and upper class vehicles and is perceived by the public as environmentally friendly. To date, however, no hybrid drive concepts suitable for mass production have been available for sports cars, such as the Porsche 911. In order to answer questions about the optimum design of hybrid drive systems for high-performance vehicles and about the use of future technologies in motor racing, Porsche Motorsport therefore developed the GT3 R Hybrid. (orig.)

  2. Repeating Marx

    DEFF Research Database (Denmark)

    Fuchs, Christian; Monticelli, Lara

    2018-01-01

    This introduction sets out the context of the special issue “Karl Marx @ 200: Debating Capitalism & Perspectives for the Future of Radical Theory”, which was published on the occasion of Marx’s bicentenary on 5 May 2018. First, we give a brief overview of contemporary capitalism’s development...... and its crises. Second, we argue that it is important to repeat Marx today. Third, we reflect on lessons learned from 200 years of struggles for alternatives to capitalism. Fourth, we give an overview of the contributions in this special issue. Taken together, the contributions in this special issue show...... that Marx’s theory and politics remain key inspirations for understanding exploitation and domination in 21st-century society and for struggles that aim to overcome these phenomena and establishing a just and fair society. We need to repeat Marx today....

  3. Deployment Repeatability

    Science.gov (United States)

    2016-08-31

    large cohort of trials to spot unusual cases. However, deployment repeatability is inherently a nonlinear phenomenon, which makes modeling difficult...and GEMS tip position were both tracked during ground testing by a laser target tracking system. Earlier SAILMAST testing in 2005 [8] used...recalls the strategy used by SRTM, where a constellation of lights was installed at the tip of the boom and a modified star tracker was used to track tip

  4. Looking for the Perfect Mentor.

    Science.gov (United States)

    Sá, Ana Pinheiro; Teixeira-Pinto, Cristina; Veríssimo, Rafaela; Vilas-Boas, Andreia; Firmino-Machado, João

    2015-01-01

    The authors established the profile of the Internal Medicine clinical teachers in Portugal aiming to define a future interventional strategy plan as adequate as possible to the target group and to the problems identified by the residents. Observational, transversal, analytic study. An online anonymous questionnaire was defined, evaluating the demographic characteristics of the clinical teachers, their path in Internal Medicine and their involvement in the residents learning process. We collected 213 valid questionnaires, making for an estimated response rate of 28.4%. Median global satisfaction with the clinical teacher was 4.52 (± 1.33 points) and the classification of the relationship between resident and clinical teacher was 4.86 ± 1.04 points. The perfect clinical teacher is defined by high standards of dedication and responsibility (4.9 ± 1.37 points), practical (4.8 ± 1.12 points) and theoretical skills (4.8 ± 1.07 points). The multiple linear regression model allowed to determine predictors of the residentâs satisfaction with their clinical teacher, justifying 82,5% of the variation of satisfaction with the clinical teacher (R2 = 0.83; R2 a = 0.82). Postgraduate medical education consists of an interaction between several areas of knowledge and intervening variables in the learning process having the clinical teacher in the central role. Overall, the pedagogical abilities were the most valued by the Internal Medicine residents regarding their clinical teacher, as determinants of a quality residentship. This study demonstrates the critical relevance of the clinical teacher in the satisfaction of residents with their residentship. The established multiple linear regression model highlights the impact of the clinical and pedagogical relantionship with the clinical teacher in a relevant increase in the satisfaction with the latter.

  5. A new characterization of trivially perfect graphs

    Directory of Open Access Journals (Sweden)

    Christian Rubio Montiel

    2015-03-01

    Full Text Available A graph $G$ is \\emph{trivially perfect} if for every induced subgraph the cardinality of the largest set of pairwise nonadjacent vertices (the stability number $\\alpha(G$ equals the number of (maximal cliques $m(G$. We characterize the trivially perfect graphs in terms of vertex-coloring and we extend some definitions to infinite graphs.

  6. FRONT AXLE OF MERCEDES AMG GT. MODELLING IN AUTODESK INVENTOR

    Directory of Open Access Journals (Sweden)

    COROLENCU Eduard – Narcis

    2017-05-01

    Full Text Available This paper analyzes the front axle of the Mercedes AMG GT model, as so as the graphical representation of the axle and of the subassemblies of suspension system and steering system, using the AutoCAD and Autodesk Inventor software. The paper include the steps for made the 3D model of the front axle in order to highlight the advantages of suspension and steering system, the function of this systems and methods for manufacturing of these. The 3D model presents a suite of complex surfaces. This type of surfaces is often designed with non-analytical means. The main commands and options used in Autodesk Inventor software were presented and explained. All the component parts of the front axle were modelled and assembled according to their functional role. Finally, the models were rendered in order to have a realistic appearance.

  7. WBP: The wood Brazilian BIG-GT demonstration project

    Energy Technology Data Exchange (ETDEWEB)

    Carpentieri, E. [Companhia Hidro Eletrica do Sao Francisco, Recife (Brazil)

    1993-12-31

    Brazil is one of the leading countries in the use of renewable energy. Most of its electricity comes from hydro power, about 200,000 barrels a day of ethanol from sugar cane is used as fuel, around 38% of the pig iron, and 20% of the steel production, uses charcoal as a reducing medium. Located in the tropics, with the sun shining all year round, and with its vast territory, the Country may be regarded as having all the basic conditions to develop a modern Biomass for Electricity industry. The conjunction of those characteristics with, the necessity of developing new energy resources for electricity production in the Northeast of the Country, the results of the studies made by Princeton University, Shell and Chesf, the progress achieved by the BIG-GT (Biomass Integrated Gasification Gas Turbine) technology in Europe, and the organization of the Global Environment Facility (GEF), provided the unique opportunity for the implementation of a commercial demonstration in Brazil. This paper describes the idea, the scope, the technical challenges, and actual status of development of the WBP, a project which aims to demonstrate the commercial viability of the BIG-GT technology. It also highlights, the project management structure, the role of the GEF, World Bank and of the United Nations Development Program (UNDP), and the participation of the Brazilian Federal Government, through the Ministry of Science and Technology (MCT). Finally it describes the Participants (ELETROBRAS, CVRD, CIENTEC, SHELL, and CHESF), their role in the project, and how the group was formed and operates.

  8. Characterization of two-qubit perfect entanglers

    International Nuclear Information System (INIS)

    Rezakhani, A.T.

    2004-01-01

    Here we consider perfect entanglers from another perspective. It is shown that there are some special perfect entanglers which can maximally entangle a full product basis. We explicitly construct a one-parameter family of such entanglers together with the proper product basis that they maximally entangle. This special family of perfect entanglers contains some well-known operators such as controlled-NOT (CNOT) and double-CNOT, but not √(SWAP). In addition, it is shown that all perfect entanglers with entangling power equal to the maximal value (2/9) are also special perfect entanglers. It is proved that the one-parameter family is the only possible set of special perfect entanglers. Also we provide an analytic way to implement any arbitrary two-qubit gate, given a proper special perfect entangler supplemented with single-qubit gates. Such gates are shown to provide a minimum universal gate construction in that just two of them are necessary and sufficient in implementation of a generic two-qubit gate

  9. Multi-channel coherent perfect absorbers

    KAUST Repository

    Bai, Ping

    2016-05-18

    The absorption efficiency of a coherent perfect absorber usually depends on the phase coherence of the incident waves on the surfaces. Here, we present a scheme to create a multi-channel coherent perfect absorber in which the constraint of phase coherence is loosened. The scheme has a multi-layer structure such that incident waves in different channels with different angular momenta can be simultaneously and perfectly absorbed. This absorber is robust in achieving high absorption efficiency even if the incident waves become "incoherent" and possess "random" wave fronts. Our work demonstrates a unique approach to designing highly efficient metamaterial absorbers. © CopyrightEPLA, 2016.

  10. On 4-critical t-perfect graphs

    OpenAIRE

    Benchetrit, Yohann

    2016-01-01

    It is an open question whether the chromatic number of $t$-perfect graphs is bounded by a constant. The largest known value for this parameter is 4, and the only example of a 4-critical $t$-perfect graph, due to Laurent and Seymour, is the complement of the line graph of the prism $\\Pi$ (a graph is 4-critical if it has chromatic number 4 and all its proper induced subgraphs are 3-colorable). In this paper, we show a new example of a 4-critical $t$-perfect graph: the complement of the line gra...

  11. Multi-channel coherent perfect absorbers

    KAUST Repository

    Bai, Ping; Wu, Ying; Lai, Yun

    2016-01-01

    The absorption efficiency of a coherent perfect absorber usually depends on the phase coherence of the incident waves on the surfaces. Here, we present a scheme to create a multi-channel coherent perfect absorber in which the constraint of phase coherence is loosened. The scheme has a multi-layer structure such that incident waves in different channels with different angular momenta can be simultaneously and perfectly absorbed. This absorber is robust in achieving high absorption efficiency even if the incident waves become "incoherent" and possess "random" wave fronts. Our work demonstrates a unique approach to designing highly efficient metamaterial absorbers. © CopyrightEPLA, 2016.

  12. Preliminary safety evaluation of the Gas Turbine-Modular Helium Reactor (GT-MHR)

    International Nuclear Information System (INIS)

    Dunn, T.D.; Lommers, L.J.; Tangirala, V.E.

    1994-04-01

    A qualitative comparison between the safety characteristics of the Gas Turbine-Modular Helium Reactor (GT-MHR) and those of the steam cycle shows that the two designs achieve equivalent levels of overall safety performance. This comparison is obtained by applying the scaling laws to detailed steam-cycle computations as well as the conclusions obtained from preliminary GT-MHR model simulations. The gas turbine design is predicted to be superior for some event categories, while the steam cycle design is better for others. From a safety perspective, the GT-MHR has a modest advantage for pressurized conduction cooldown events. Recent computational simulations of 102 column, 550 MW(t) GT-MHR during a depressurized conduction cooldown show that peak fuel temperatures are within the limits. The GT-MHR has a significantly lower risk due to water ingress events under operating conditions. Two additional scenarios, namely loss of load event and turbine deblading event that are specific to the GT-MHR design are discussed. Preliminary evaluation of the GT-MHR's safety characteristics indicate that the GT-MHR can be expected to satisfy or exceed its safety requirements

  13. Helium turbomachine design for GT-MHR power plant

    International Nuclear Information System (INIS)

    McDonald, C.F.; Orlando, R.J.

    1994-07-01

    The power conversion system in the gas turbine modular helium reactor (GT-MHR) power plant is based on a highly recuperated closed Brayton cycle. The major component in the direct cycle system is a helium closed-cycle gas turbine rated at 286 MW(e). The rotating group consists of an intercooled helium turbocompressor coupled to a synchronous generator. The vertical rotating assembly is installed in a steel vessel, together with the other major components (i.e., recuperator, precooler, intercooler, and connecting ducts and support structures). The rotor is supported on an active magnetic bearing system. The turbine operates directly on the reactor helium coolant, and with a temperature of 850 degree C (1562 degree F) the plant efficiency is over 47%. This paper addresses the design and development planning of the helium turbomachine, and emphasizes that with the utilization of proven technology, this second generation nuclear power plant could be in service in the first decade of the 21st century

  14. Overlapped optics induced perfect coherent effects

    Science.gov (United States)

    Li, Jian Jie; Zang, Xiao Fei; Mao, Jun Fa; Tang, Min; Zhu, Yi Ming; Zhuang, Song Lin

    2013-12-01

    For traditional coherent effects, two separated identical point sources can be interfered with each other only when the optical path difference is integer number of wavelengths, leading to alternate dark and bright fringes for different optical path difference. For hundreds of years, such a perfect coherent condition seems insurmountable. However, in this paper, based on transformation optics, two separated in-phase identical point sources can induce perfect interference with each other without satisfying the traditional coherent condition. This shifting illusion media is realized by inductor-capacitor transmission line network. Theoretical analysis, numerical simulations and experimental results are performed to confirm such a kind of perfect coherent effect and it is found that the total radiation power of multiple elements system can be greatly enhanced. Our investigation may be applicable to National Ignition Facility (NIF), Inertial Confined Fusion (ICF) of China, LED lighting technology, terahertz communication, and so on.

  15. Optimal simulation of a perfect entangler

    International Nuclear Information System (INIS)

    Yu Nengkun; Duan Runyao; Ying Mingsheng

    2010-01-01

    A 2 x 2 unitary operation is called a perfect entangler if it can generate a maximally entangled state from some unentangled input. We study the following question: How many runs of a given two-qubit entangling unitary operation are required to simulate some perfect entangler with one-qubit unitary operations as free resources? We completely solve this problem by presenting an analytical formula for the optimal number of runs of the entangling operation. Our result reveals an entanglement strength of two-qubit unitary operations.

  16. Perfect 800 Advanced Strategies for Top Students

    CERN Document Server

    Celenti, Dan

    2010-01-01

    Getting into the nation's most competitive universities requires more than a good SAT score, it requires a perfect score. Perfect 800: SAT Math gives advanced students the tools needed to master the SAT math test. Covering areas including arithmetic concepts; algebra; geometry; and additional topics such as probability and weighted average, the book offers exposure to a wide range of degrees of difficulty in a holistic approach that allows students to experience the "real thing," including the impact of time constraints on their performance. By emphasizing critical thinking and analytic skills

  17. A Hypergraph Dictatorship Test with Perfect Completeness

    Science.gov (United States)

    Chen, Victor

    A hypergraph dictatorship test is first introduced by Samorodnitsky and Trevisan and serves as a key component in their unique games based {operatorname{PCP}} construction. Such a test has oracle access to a collection of functions and determines whether all the functions are the same dictatorship, or all their low degree influences are o(1). Their test makes q ≥ 3 queries, has amortized query complexity 1+Oleft(log q/qright), but has an inherent loss of perfect completeness. In this paper we give an (adaptive) hypergraph dictatorship test that achieves both perfect completeness and amortized query complexity 1+Oleft(log q/qright).

  18. Perfect and Periphrastic Passive Constructions in Danish

    DEFF Research Database (Denmark)

    Bjerre, Tavs; Bjerre, Anne

    2007-01-01

    This paper gives an account of the event and argument structure of past participles and the linking between argument structure and valence structure. It further accounts for how participles form perfect and passiv constructions with auxiliaries. We assume that the same participle form is used...... in both types of construction. Our claim is that the valence structure of a past participle is predictable from its semantic type, and that the valence structure predicts with which auciliary a past participle combines in perfect constructions and whether the past participle may occur in passiv...

  19. Optically Modulated Multiband Terahertz Perfect Absorber

    DEFF Research Database (Denmark)

    Seren, Huseyin R.; Keiser, George R.; Cao, Lingyue

    2014-01-01

    response of resonant metamaterials continues to be a challengingendeavor. Resonant perfect absorbers have flourished as one of the mostpromising metamaterial devices with applications ranging from power har-vesting to terahertz imaging. Here, an optically modulated resonant perfectabsorber is presented....... Utilizing photo-excited free carriers in silicon padsplaced in the capacitive gaps of split ring resonators, a dynamically modu-lated perfect absorber is designed and fabricated to operate in reflection.Large modulation depth (38% and 91%) in two absorption bands (with 97%and 92% peak absorption...

  20. Optimization of Perfect Absorbers with Multilayer Structures

    Science.gov (United States)

    Li Voti, Roberto

    2018-02-01

    We study wide-angle and broadband perfect absorbers with compact multilayer structures made of a sequence of ITO and TiN layers deposited onto a silver thick layer. An optimization procedure is introduced for searching the optimal thicknesses of the layers so as to design a perfect broadband absorber from 400 nm to 750 nm, for a wide range of angles of incidence from 0{°} to 50{°}, for both polarizations and with a low emissivity in the mid-infrared. We eventually compare the performances of several optimal structures that can be very promising for solar thermal energy harvesting and collectors.

  1. Electromagnetic Detection of a Perfect Invisibility Cloak

    International Nuclear Information System (INIS)

    Zhang Baile; Wu, Bae-Ian

    2009-01-01

    A perfect invisibility cloak is commonly believed to be undetectable from electromagnetic (EM) detection because it is equivalent to a curved but empty EM space created from coordinate transformation. Based on the intrinsic asymmetry of coordinate transformation applied to motions of photons and charges, we propose a method to detect this curved EM space by shooting a fast-moving charged particle through it. A broadband radiation generated in this process makes a cloak visible. Our method is the only known EM mechanism so far to detect an ideal perfect cloak (curved EM space) within its working band.

  2. Lattice-Like Total Perfect Codes

    Directory of Open Access Journals (Sweden)

    Araujo Carlos

    2014-02-01

    Full Text Available A contribution is made to the classification of lattice-like total perfect codes in integer lattices Λn via pairs (G, Φ formed by abelian groups G and homomorphisms Φ: Zn → G. A conjecture is posed that the cited contribution covers all possible cases. A related conjecture on the unfinished work on open problems on lattice-like perfect dominating sets in Λn with induced components that are parallel paths of length > 1 is posed as well.

  3. Comparison of Raw Acceleration from the GENEA and ActiGraph™ GT3X+ Activity Monitors

    Directory of Open Access Journals (Sweden)

    Dinesh John

    2013-10-01

    Full Text Available Purpose: To compare raw acceleration output of the ActiGraph™ GT3X+ and GENEA activity monitors. Methods: A GT3X+ and GENEA were oscillated in an orbital shaker at frequencies ranging from 0.7 to 4.0 Hz (ten 2-min trials/frequency on a fixed radius of 5.08 cm. Additionally, 10 participants (age = 23.8 ± 5.4 years wore the GT3X+ and GENEA on the dominant wrist and performed treadmill walking (2.0 and 3.5 mph and running (5.5 and 7.5 mph and simulated free-living activities (computer work, cleaning a room, vacuuming and throwing a ball for 2-min each. A linear mixed model was used to compare the mean triaxial vector magnitude (VM from the GT3X+ and GENEA at each oscillation frequency. For the human testing protocol, random forest machine-learning technique was used to develop two models using frequency domain (FD and time domain (TD features for each monitor. We compared activity type recognition accuracy between the GT3X+ and GENEA when the prediction model was fit using one monitor and then applied to the other. Z-statistics were used to compare the proportion of accurate predictions from the GT3X+ and GENEA for each model. Results: GENEA produced significantly higher (p < 0.05, 3.5 to 6.2% mean VM than GT3X+ at all frequencies during shaker testing. Training the model using TD input features on the GENEA and applied to GT3X+ data yielded significantly lower (p < 0.05 prediction accuracy. Prediction accuracy was not compromised when interchangeably using FD models between monitors. Conclusions: It may be inappropriate to apply a model developed on the GENEA to predict activity type using GT3X+ data when input features are TD attributes of raw acceleration.

  4. Multi-color lightcurve observation of the asteroid (163249) 2002 GT

    Science.gov (United States)

    Oshima, M.; Abe, S.

    2014-07-01

    NASA's Deep Impact/EPOXI spacecraft plans to encounter the asteroid (163249) 2002 GT, classified as a PHA (Potentially Hazardous Asteroid), on January 4, 2020. However, the taxonomic type and spin state of 2002 GT remain to be determined. We have carried out ground-based multi-color (B-V-R-I) lightcurve observations taking advantage of the 2002 GT Characterization Campaign by NASA. Multi-color lightcurve measurements allow us to estimate the rotation period and obtain strong constraints on the shape and pole orientation. Here we found that the rotation period of 2002 GT is estimated to be 3.7248 ± 0.1664 h. In mid-2013, 2002 GT passed at 0.015 au from the Earth, resulting an exceptional opportunity for ground-based characterization. Using the 0.81-m telescope of the Tenagra Observatory (110°52'44.8''W, +31°27'44.4''N, 1312 m) in Arizona, USA, and the Johnson-Cousins BVRI filters, we have found lightcurves of 2002 GT (Figure). The Tenagra II 0.81-m telescope is used for research of the Hayabusa2 target Asteroid (162173) 1999 JU_3. The lightcurves (relative magnitude) show that the rotation period of 2002 GT, the target of NASA's Deep Impact/EPOXI spacecraft, is estimated to be 3.7248 ± 0.1664 hr. On June 9, 2013, we had 7 hours of ground-based observations on 2002 GT from 4:00 to 11:00 UTC. The number of comparison stars for differential photometry was 34. Because of tracking the fast-moving asteroid, it was necessary to have the same comparison star among the fields of vision. We have also obtained absolute photometry of 2002 GT on June 13, 2013.

  5. Dynamics and control modeling of the closed-cycle gas turbine (GT-HTGR) power plant

    International Nuclear Information System (INIS)

    Bardia, A.

    1980-02-01

    The simulation if presented for the 800-MW(e) two-loop GT-HTGR plant design with the REALY2 transient analysis computer code, and the modeling of control strategies called for by the inherently unique operational requirements of a multiple loop GT-HTGR is described. Plant control of the GT-HTGR is constrained by the nature of its power conversion loops (PCLs) in which the core cooling flow and the turbine flow are directly related and thus changes in flow affect core cooling as well as turbine power. Additionally, the high thermal inertia of the reactor core precludes rapid changes in the temperature of the turbine inlet flow

  6. Mechanical Energy Changes in Perfectly Inelastic Collisions

    Science.gov (United States)

    Mungan, Carl E.

    2013-01-01

    Suppose a block of mass "m"[subscript 1] traveling at speed "v"[subscript 1] makes a one-dimensional perfectly inelastic collision with another block of mass "m"[subscript 2]. What else does one need to know to calculate the fraction of the mechanical energy that is dissipated in the collision? (Contains 1 figure.)

  7. The Present Perfect in World Englishes

    Science.gov (United States)

    Yao, Xinyue; Collins, Peter

    2012-01-01

    This paper reports on a comprehensive corpus-based study of regional and stylistic variation in the distribution of the English present perfect. The data represents ten English varieties of both the Inner Circle and Outer Circle, covering four major text types: conversation, news reportage, academic and fictional writing. The results are discussed…

  8. Le Perfectionnement en Phonetique (Perfecting Phonetics)

    Science.gov (United States)

    Laroche-Bouvy, Danielle

    1975-01-01

    This article describes the programs of the Institut d'Etudes Linguistiques et Phonetiques, located in Paris. The program focuses on perfecting the students' phonetic production of French. Both curriculum and teaching methods are described, as well as a course in phonetics for future teachers of French. (Text is in French.) (CLK)

  9. Maple Explorations, Perfect Numbers, and Mersenne Primes

    Science.gov (United States)

    Ghusayni, B.

    2005-01-01

    Some examples from different areas of mathematics are explored to give a working knowledge of the computer algebra system Maple. Perfect numbers and Mersenne primes, which have fascinated people for a very long time and continue to do so, are studied using Maple and some questions are posed that still await answers.

  10. Perfectly Secure Oblivious RAM without Random Oracles

    DEFF Research Database (Denmark)

    Damgård, Ivan Bjerre; Meldgaard, Sigurd Torkel; Nielsen, Jesper Buus

    2011-01-01

    We present an algorithm for implementing a secure oblivious RAM where the access pattern is perfectly hidden in the information theoretic sense, without assuming that the CPU has access to a random oracle. In addition we prove a lower bound on the amount of randomness needed for implementing...

  11. Reshaping the perfect electrical conductor cylinder arbitrarily

    International Nuclear Information System (INIS)

    Chen Huanyang; Zhang Xiaohe; Luo Xudong; Ma Hongru; Chan Cheting

    2008-01-01

    A general method is proposed to design a cylindrical cloak, concentrator and superscatterer with an arbitrary cross section. The method is demonstrated by the design of a perfect electrical conductor (PEC) reshaper which is able to reshape a PEC cylinder arbitrarily by combining the concept of cloak, concentrator and superscatterer together. Numerical simulations are performed to demonstrate its properties.

  12. What is anthropological about The Perfect Human?

    DEFF Research Database (Denmark)

    Thomsen, Line Hassall

    2015-01-01

    Jørgen Leth has classified The Perfect Human as an anthropological film. But is the film anthropological at all? This article explores Leth’s connections with anthropology and finds that he is more inspired by anthropological framing than he is by anthropological research methods....

  13. Abundance and Characterization of Perfect Microsatellites on the Cattle Y Chromosome.

    Science.gov (United States)

    Ma, Zhi-Jie

    2017-07-03

    Microsatellites or simple sequence repeats (SSRs) are found in most organisms and play an important role in genomic organization and function. To characterize the abundance of SSRs (1-6 base-pairs [bp]) on the cattle Y chromsome, the relative frequency and density of perfect or uninterrupted SSRs based on the published Y chromosome sequence were examined. A total of 17,273 perfect SSRs were found, with total length of 324.78 kb, indicating that approximately 0.75% of the cattle Y chromosome sequence (43.30 Mb) comprises perfect SSRs, with an average length of 18.80 bp. The relative frequency and density were 398.92 loci/Mb and 7500.62 bp/Mb, respectively. The proportions of the six classes of perfect SSRs were highly variable on the cattle Y chromosome. Mononucleotide repeats had a total number of 8073 (46.74%) and an average length of 15.45 bp, and were the most abundant SSRs class, while the percentages of di-, tetra-, tri-, penta-, and hexa-nucleotide repeats were 22.86%, 11.98%, 11.58%, 6.65%, and 0.19%, respectively. Different classes of SSRs varied in their repeat number, with the highest being 42 for dinucleotides. Results reveal that repeat categories A, AC, AT, AAC, AGC, GTTT, CTTT, ATTT, and AACTG predominate on the Y chromosome. This study provides insight into the organization of cattle Y chromosome repetitive DNA, as well as information useful for developing more polymorphic cattle Y-chromosome-specific SSRs.

  14. Physical Activity Assessment with the ActiGraph GT3X and Doubly Labeled Water.

    Science.gov (United States)

    Chomistek, Andrea K; Yuan, Changzheng; Matthews, Charles E; Troiano, Richard P; Bowles, Heather R; Rood, Jennifer; Barnett, Junaidah B; Willett, Walter C; Rimm, Eric B; Bassett, David R

    2017-09-01

    To compare the degree to which four accelerometer metrics-total activity counts per day (TAC per day), steps per day (steps per day), physical activity energy expenditure (PAEE) (kcal·kg·d), and moderate- to vigorous-intensity physical activity (MVPA) (min·d)-were correlated with PAEE measured by doubly labeled water (DLW). Additionally, accelerometer metrics based on vertical axis counts and triaxial counts were compared. This analysis included 684 women and 611 men age 43 to 83 yr. Participants wore the Actigraph GT3X on the hip for 7 d twice during the study and the average of the two measurements was used. Each participant also completed one DLW measurement, with a subset having a repeat. PAEE was estimated by subtracting resting metabolic rate and the thermic effect of food from total daily energy expenditure estimated by DLW. Partial Spearman correlations were used to estimate associations between PAEE and each accelerometer metric. Correlations between the accelerometer metrics and DLW-determined PAEE were higher for triaxial counts than vertical axis counts. After adjusting for weight, age, accelerometer wear time, and fat free mass, the correlation between TAC per day based on triaxial counts and DLW-determined PAEE was 0.44 in women and 0.41 in men. Correlations for steps per day and accelerometer-estimated PAEE with DLW-determined PAEE were similar. After adjustment for within-person variation in DLW-determined PAEE, the correlations for TAC per day increased to 0.61 and 0.49, respectively. Correlations between MVPA and DLW-determined PAEE were lower, particularly for modified bouts of ≥10 min. Accelerometer measures that represent total activity volume, including TAC per day, steps per day, and PAEE, were more highly correlated with DLW-determined PAEE than MVPA using traditional thresholds and should be considered by researchers seeking to reduce accelerometer data to a single metric.

  15. Development of teaching material to integrate GT-POWER into combustion courses for IC engine simulations.

    Science.gov (United States)

    2009-02-01

    The main objective of this project was to develop instructional engineering projects that utilize the newly-offered PACE software GT-POWER for engine simulations in combustion-related courses at the Missouri University of Science and Technology. Stud...

  16. INTEGRAL/JEM-X detection of fading emission from GT Mus

    DEFF Research Database (Denmark)

    Fiocchi, M.; Chenevez, J.; Sguera, V.

    2015-01-01

    On November 15th 2015 the MAXI/GSC detected a big flare from the RS CVn star GT Mus with a flux of ~100 mCrab in the 2-20 keV energy band. (ATel #8285). During recent INTEGRAL observations of the Musca region performed between 17 Nov 16:08 and 18 Nov 00:05 (UTC) the source GT Mus was within the f...

  17. STAT4 rs7574865 G/T and PTPN22 rs2488457 G/C polymorphisms influence the risk of developing juvenile idiopathic arthritis in Han Chinese patients.

    Science.gov (United States)

    Fan, Zhi-Dan; Wang, Fei-Fei; Huang, Hui; Huang, Na; Ma, Hui-Hui; Guo, Yi-Hong; Zhang, Ya-Yuan; Qian, Xiao-Qing; Yu, Hai-Guo

    2015-01-01

    Juvenile idiopathic arthritis (JIA) is a common autoimmune disease characterized by environmental influences along with several predisposing genes in the pathogenesis. The protein tyrosine phosphatase nonreceptor 22 (PTPN22) and signal transducer and activator of transcription factor 4 (STAT4) have been recognized as susceptibility genes for numerous autoimmune diseases. Associations of STAT4 rs7574865 G/T and PTPN22 (rs2488457 G/C and rs2476601 C/T) polymorphisms with JIA have repeatedly been replicated in several Caucasian populations. The aim of this study was to investigate the influence of three polymorphisms mentioned above on the risk of developing JIA in Han Chinese patients. Genotyping was performed on a total of 137 Chinese patients with JIA (JIA group) and 150 sex and age frequency-matched healthy volunteers (Control group). The single-nucleotide polymorphisms (SNP) were determined by using direct sequencing of PCR-amplified products. There were significant differences of PTPN22 rs2488457 G/C and STAT4 rs7574865 G/T polymorphisms between both groups. However, no significant difference was observed in distribution frequencies of PTPN22 rs2476601 polymorphism. The association with the PTPN22 rs2488457 G/C polymorphism remained significant in the stratifications by age at onset, ANA status, splenomegaly, lymphadenectasis and involvement joints. As with the STAT4 rs7574865 G/T polymorphisms, the enthesitis-related arthritis and presence of hepatomegaly had strong effect on the association. Our data strengthen STAT4 rs7574865 G/T and PTPN22 rs2488457 G/C polymorphisms as susceptibility factors for JIA.

  18. STAT4 rs7574865 G/T and PTPN22 rs2488457 G/C polymorphisms influence the risk of developing juvenile idiopathic arthritis in Han Chinese patients.

    Directory of Open Access Journals (Sweden)

    Zhi-Dan Fan

    Full Text Available Juvenile idiopathic arthritis (JIA is a common autoimmune disease characterized by environmental influences along with several predisposing genes in the pathogenesis. The protein tyrosine phosphatase nonreceptor 22 (PTPN22 and signal transducer and activator of transcription factor 4 (STAT4 have been recognized as susceptibility genes for numerous autoimmune diseases. Associations of STAT4 rs7574865 G/T and PTPN22 (rs2488457 G/C and rs2476601 C/T polymorphisms with JIA have repeatedly been replicated in several Caucasian populations. The aim of this study was to investigate the influence of three polymorphisms mentioned above on the risk of developing JIA in Han Chinese patients. Genotyping was performed on a total of 137 Chinese patients with JIA (JIA group and 150 sex and age frequency-matched healthy volunteers (Control group. The single-nucleotide polymorphisms (SNP were determined by using direct sequencing of PCR-amplified products. There were significant differences of PTPN22 rs2488457 G/C and STAT4 rs7574865 G/T polymorphisms between both groups. However, no significant difference was observed in distribution frequencies of PTPN22 rs2476601 polymorphism. The association with the PTPN22 rs2488457 G/C polymorphism remained significant in the stratifications by age at onset, ANA status, splenomegaly, lymphadenectasis and involvement joints. As with the STAT4 rs7574865 G/T polymorphisms, the enthesitis-related arthritis and presence of hepatomegaly had strong effect on the association. Our data strengthen STAT4 rs7574865 G/T and PTPN22 rs2488457 G/C polymorphisms as susceptibility factors for JIA.

  19. Nonminimal coupling of perfect fluids to curvature

    International Nuclear Information System (INIS)

    Bertolami, Orfeu; Lobo, Francisco S. N.; Paramos, Jorge

    2008-01-01

    In this work, we consider different forms of relativistic perfect fluid Lagrangian densities that yield the same gravitational field equations in general relativity (GR). A particularly intriguing example is the case with couplings of the form [1+f 2 (R)]L m , where R is the scalar curvature, which induces an extra force that depends on the form of the Lagrangian density. It has been found that, considering the Lagrangian density L m =p, where p is the pressure, the extra-force vanishes. We argue that this is not the unique choice for the matter Lagrangian density, and that more natural forms for L m do not imply the vanishing of the extra force. Particular attention is paid to the impact on the classical equivalence between different Lagrangian descriptions of a perfect fluid.

  20. Thermodynamical stability for a perfect fluid

    Energy Technology Data Exchange (ETDEWEB)

    Fang, Xiongjun; Jing, Jiliang [Hunan Normal University, Department of Physics, Key Laboratory of Low Dimensional Quantum Structures and Quantum Control of Ministry of Education, and Synergetic Innovation Center for Quantum Effects and Applications, Changsha, Hunan (China); He, Xiaokai [Hunan Normal University, Department of Physics, Key Laboratory of Low Dimensional Quantum Structures and Quantum Control of Ministry of Education, and Synergetic Innovation Center for Quantum Effects and Applications, Changsha, Hunan (China); Hunan First Normal University, School of Mathematics and Computational Science, Changsha (China)

    2017-12-15

    According to the maximum entropy principle, it has been proved that the gravitational field equations could be derived by the extrema of the total entropy for a perfect fluid, which implies that thermodynamic relations contain information as regards gravity. In this manuscript, we obtain a criterion for the thermodynamical stability of an adiabatic, self-gravitating perfect fluid system by the second variation of the total entropy. We show, for Einstein's gravity with spherical symmetry spacetime, that the criterion is consistent with that for the dynamical stability derived by Chandrasekhar and Wald. We also find that the criterion could be applied to cases without spherical symmetry, or under general perturbations. The result further establishes the connection between thermodynamics and gravity. (orig.)

  1. Physicotechnical potentialities of perfecting roentgenographic research

    International Nuclear Information System (INIS)

    Chikirdin, Eh.G.; Mishkinis, B.Ya.

    1991-01-01

    Physicotechnical potentialities of perfecting image quality in X-ray examinations are enumerated. Realization of these potentialities demands interrelated decision of two problems: substantiation of optimizing conditions of survey (postures of a patient, geometry of investigation, image converters, electric regimes), creation of adequate hardware and software components. It is shown that introduction of X-ray feeding device with microprocessor control permits to upgrade the quality of X-ray images and to reduce radiation loads of a patient

  2. Perfect Fluid Theory and its Extensions

    OpenAIRE

    Jackiw, R.; Nair, V. P.; Pi, S. -Y.; Polychronakos, A. P.

    2004-01-01

    We review the canonical theory for perfect fluids, in Eulerian and Lagrangian formulations. The theory is related to a description of extended structures in higher dimensions. Internal symmetry and supersymmetry degrees of freedom are incorporated. Additional miscellaneous subjects that are covered include physical topics concerning quantization, as well as mathematical issues of volume preserving diffeomorphisms and representations of Chern-Simons terms (= vortex or magnetic helicity).

  3. Perfect fluid cosmology with geodesic world lines

    International Nuclear Information System (INIS)

    Raychaudhuri, A.K.; Maity, S.R.

    1978-01-01

    It is shown that for a perfect fluid with an equation of state p = p (rho), if the world lines are geodesics, then they are hypersurface orthogonal and the scalars p, rho, sigma 2 , and theta 2 are all constants over these hypersurfaces, irrespective of any spatial-homogeneity assumption. However, an examination of some simple cases does not reveal any spatially nonhomogeneous solution with these properties

  4. Comment on 'Perfect imaging without negative refraction'

    Science.gov (United States)

    Blaikie, R. J.

    2010-05-01

    The prediction of 'perfect' imaging without negative refraction for Maxwell's fish-eye lens (Leonhardt U 2009 New J. Phys. 11 093040) is a consequence of imposing an active localized 'drain' at the image point rather than being a general property of the lens. This work then becomes analogous to other work using time-reversal symmetry and/or structured antennae to achieve super-resolution, which can be applied to many types of imaging system beyond the fish-eye lens.

  5. Comment on 'Perfect imaging without negative refraction'

    International Nuclear Information System (INIS)

    Blaikie, R J

    2010-01-01

    The prediction of 'perfect' imaging without negative refraction for Maxwell's fish-eye lens (Leonhardt U 2009 New J. Phys. 11 093040) is a consequence of imposing an active localized 'drain' at the image point rather than being a general property of the lens. This work then becomes analogous to other work using time-reversal symmetry and/or structured antennae to achieve super-resolution, which can be applied to many types of imaging system beyond the fish-eye lens.

  6. Inequivalent quantizations and fundamentally perfect spaces

    International Nuclear Information System (INIS)

    Imbo, T.D.; Sudarshan, E.C.G.

    1987-06-01

    We investigate the problem of inequivalent quantizations of a physical system with multiply connected configuration space X. For scalar quantum theory on X we show that state vectors must be single-valued if and only if the first homology group H 1 (X) is trivial, or equivalently the fundamental group π 1 (X) is perfect. The θ-structure of quantum gauge and gravitational theories is discussed in light of this result

  7. Another Class of Perfect Nonlinear Polynomial Functions

    Directory of Open Access Journals (Sweden)

    Menglong Su

    2013-01-01

    Full Text Available Perfect nonlinear (PN functions have been an interesting subject of study for a long time and have applications in coding theory, cryptography, combinatorial designs, and so on. In this paper, the planarity of the trinomials xpk+1+ux2+vx2pk over GF(p2k are presented. This class of PN functions are all EA-equivalent to x2.

  8. A note on perfect scalar fields

    International Nuclear Information System (INIS)

    Unnikrishnan, Sanil; Sriramkumar, L.

    2010-01-01

    We derive a condition on the Lagrangian density describing a generic, single, noncanonical scalar field, by demanding that the intrinsic, nonadiabatic pressure perturbation associated with the scalar field vanishes identically. Based on the analogy with perfect fluids, we refer to such fields as perfect scalar fields. It is common knowledge that models that depend only on the kinetic energy of the scalar field (often referred to as pure kinetic models) possess no nonadiabatic pressure perturbation. While we are able to construct models that seemingly depend on the scalar field and also do not contain any nonadiabatic pressure perturbation, we find that all such models that we construct allow a redefinition of the field under which they reduce to pure kinetic models. We show that, if a perfect scalar field drives inflation, then, in such situations, the first slow roll parameter will always be a monotonically decreasing function of time. We point out that this behavior implies that these scalar fields cannot lead to features in the inflationary, scalar perturbation spectrum.

  9. Utilization of waste heat from GT-MHR for power generation in organic Rankine cycles

    International Nuclear Information System (INIS)

    Yari, Mortaza; Mahmoudi, S.M.S.

    2010-01-01

    The gas turbine-modular helium reactor (GT-MHR) is currently being developed by an international consortium. In this power plant, circulating helium that has to be compressed in a single or two successive stages cools the reactor core. For thermodynamic reasons, these compression stages require pre-cooling of the helium to about 26 deg. C through the use of intercooler and pre-cooler in which water is used to cool the helium. Considerable thermal energy (∼300 MWth) is thus dissipated in these components. This thermal energy is then rejected to a heat sink. For different designs, the temperature ranges of the helium in the intercooler and pre-cooler could be about 100 and 150 deg. C, respectively. These are ideal energy sources to be used in an organic Rankine cycles for power generation. This study examines the performance of a gas-cooled nuclear power plant with closed Brayton cycle (CBC) combined with two organic Rankine cycles (ORC). More attention was paid to the irreversibilities generated in the combined cycle. Individual models are developed for each component through applications of the first and second laws of thermodynamics. The effects of the turbine inlet temperature, compressor pressure ratio, evaporator temperature and temperature difference in the evaporator on the first- and second-law efficiencies and on the exergy destruction rate of the combined cycle were studied. Finally the combined cycle was optimized thermodynamically using the EES (Engineering Equation Solver) software. Based on identical operating conditions, a comparison between the GT-MHR/ORC and a simple GT-MHR cycle is also made. It was found that both the first- and second-law efficiencies of GT-MHR/ORC cycle are about 3%-points higher than that of the simple GT-MHR cycle. Also, the exergy destruction rate for GT-MHR/ORC cycle is about 5% lower than that of the GT-MHR cycle.

  10. A thermodynamic study of waste heat recovery from GT-MHR using organic Rankine cycles

    International Nuclear Information System (INIS)

    Yari, Mortaza; Mahmoudi, S.M.S.

    2011-01-01

    This paper presents an investigation on the utilization of waste heat from a gas turbine-modular helium reactor (GT-MHR) using different arrangements of organic Rankine cycles (ORCs) for power production. The considered organic Rankine cycles were: simple organic Rankine cycle (SORC), ORC with internal heat exchanger (HORC) and regenerative organic Rankine cycle (RORC). The performances of the combined cycles were studied from the point of view of first and second-laws of thermodynamics. Individual models were developed for each component and the effects of some important parameters such as compressor pressure ratio, turbine inlet temperature, and evaporator and environment temperatures on the efficiencies and on the exergy destruction rate were studied. Finally the combined cycles were optimized thermodynamically using the EES (Engineering Equation Solver) software. Based on the identical operating conditions for the GT-MHR cycle, a comparison between the three combined cycles and a simple GT-MHR cycle is also were made. This comparison was also carried out from the point of view of economics. The GT-MHR/SORC combined cycle proved to be the best among all the cycles from the point of view of both thermodynamics and economics. The efficiency of this cycle was about 10% higher than that of GT-MHR alone. (orig.)

  11. Learning, Teaching, and Turn Taking in the Repeated Assignment Game

    OpenAIRE

    Timothy N. Cason; Sau-Him Paul Lau; Vai-Lam Mui

    2011-01-01

    History-dependent strategies are often used to support cooperation in repeated game models. Using the indefinitely repeated common-pool resource assignment game and a perfect stranger experimental design, this paper reports novel evidence that players who have successfully used an efficiency-enhancing turn-taking strategy will teach other players in subsequent supergames to adopt this strategy. We find that subjects engage in turn taking frequently in both the Low Conflict and the High Confli...

  12. On the perfect hexagonal packing of rods

    International Nuclear Information System (INIS)

    Starostin, E L

    2006-01-01

    In most cases the hexagonal packing of fibrous structures or rods extremizes the energy of interaction between strands. If the strands are not straight, then it is still possible to form a perfect hexatic bundle. Conditions under which the perfect hexagonal packing of curved tubular structures may exist are formulated. Particular attention is given to closed or cycled arrangements of the rods like in the DNA toroids and spools. The closure or return constraints of the bundle result in an allowable group of automorphisms of the cross-sectional hexagonal lattice. The structure of this group is explored. Examples of open helical-like and closed toroidal-like bundles are presented. An expression for the elastic energy of a perfectly packed bundle of thin elastic rods is derived. The energy accounts for both the bending and torsional stiffnesses of the rods. It is shown that equilibria of the bundle correspond to solutions of a variational problem formulated for the curve representing the axis of the bundle. The functional involves a function of the squared curvature under the constraints on the total torsion and the length. The Euler-Lagrange equations are obtained in terms of curvature and torsion and due to the existence of the first integrals the problem is reduced to the quadrature. The three-dimensional shape of the bundle may be readily reconstructed by integration of the Ilyukhin-type equations in special cylindrical coordinates. The results are of universal nature and are applicable to various fibrous structures, in particular, to intramolecular liquid crystals formed by DNA condensed in toroids or packed inside the viral capsids

  13. Diamagnetic expansions for perfect quantum gases

    DEFF Research Database (Denmark)

    Briet, Philippe; Cornean, Horia; Louis, Delphine

    2006-01-01

    In this work we study the diamagnetic properties of a perfect quantum gas in the presence of a constant magnetic field of intensity B. We investigate the Gibbs semigroup associated with the one particle operator at finite volume, and study its Taylor series with respect to the field parameter ome......:=eB/c in different topologies. This allows us to prove the existence of the thermodynamic limit for the pressure and for all its derivatives with respect to omega (the so-called generalized susceptibilities)....

  14. Black hole formation in perfect fluid collapse

    International Nuclear Information System (INIS)

    Goswami, Rituparno; Joshi, Pankaj S

    2004-01-01

    We construct here a special class of perfect fluid collapse models which generalizes the homogeneous dust collapse solution in order to include nonzero pressures and inhomogeneities into evolution. It is shown that a black hole is necessarily generated as the end product of continued gravitational collapse, rather than a naked singularity. We examine the nature of the central singularity forming as a result of endless collapse and it is shown that no nonspacelike trajectories can escape from the central singularity. Our results provide some insights into how the dynamical collapse works and into the possible formulations of the cosmic censorship hypothesis, which is as yet a major unsolved problem in black hole physics

  15. Explaining evolution via constrained persistent perfect phylogeny

    Science.gov (United States)

    2014-01-01

    Background The perfect phylogeny is an often used model in phylogenetics since it provides an efficient basic procedure for representing the evolution of genomic binary characters in several frameworks, such as for example in haplotype inference. The model, which is conceptually the simplest, is based on the infinite sites assumption, that is no character can mutate more than once in the whole tree. A main open problem regarding the model is finding generalizations that retain the computational tractability of the original model but are more flexible in modeling biological data when the infinite site assumption is violated because of e.g. back mutations. A special case of back mutations that has been considered in the study of the evolution of protein domains (where a domain is acquired and then lost) is persistency, that is the fact that a character is allowed to return back to the ancestral state. In this model characters can be gained and lost at most once. In this paper we consider the computational problem of explaining binary data by the Persistent Perfect Phylogeny model (referred as PPP) and for this purpose we investigate the problem of reconstructing an evolution where some constraints are imposed on the paths of the tree. Results We define a natural generalization of the PPP problem obtained by requiring that for some pairs (character, species), neither the species nor any of its ancestors can have the character. In other words, some characters cannot be persistent for some species. This new problem is called Constrained PPP (CPPP). Based on a graph formulation of the CPPP problem, we are able to provide a polynomial time solution for the CPPP problem for matrices whose conflict graph has no edges. Using this result, we develop a parameterized algorithm for solving the CPPP problem where the parameter is the number of characters. Conclusions A preliminary experimental analysis shows that the constrained persistent perfect phylogeny model allows to

  16. Selective tumor cell death induced by irradiated riboflavin through recognizing DNA G-T mismatch.

    Science.gov (United States)

    Yuan, Yi; Zhao, Yongyun; Chen, Lianqi; Wu, Jiasi; Chen, Gangyi; Li, Sheng; Zou, Jiawei; Chen, Rong; Wang, Jian; Jiang, Fan; Tang, Zhuo

    2017-09-06

    Riboflavin (vitamin B2) has been thought to be a promising antitumoral agent in photodynamic therapy, though the further application of the method was limited by the unclear molecular mechanism. Our work reveals that riboflavin was able to recognize G-T mismatch specifically and induce single-strand breaks in duplex DNA targets efficiently under irradiation. In the presence of riboflavin, the photo-irradiation could induce the death of tumor cells that are defective in mismatch repair system selectively, highlighting the G-T mismatch as potential drug target for tumor cells. Moreover, riboflavin is a promising leading compound for further drug design due to its inherent specific recognition of the G-T mismatch. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  17. Microsatellite D21D210 (GT-12) allele frequencies in sporadic Alzheimer's disease

    International Nuclear Information System (INIS)

    Lannfelt, L.; Lilius, L.; Viitanen, M.; Winblad, B.; Basun, H.; Houlden, H.; Rossor, M.; Hardy, J.

    1995-01-01

    Four disease-causing mutations have so far been described in the amyloid precursor protein gene on chromosome 21 in familial early-onset Alzheimer's disease. Linkage analysis with a fourteen-allele microsatellite at D21S210 named GT-12 has proven useful in the elucidation of amyloid presursor protein gene involvement in Alzheimer's disease families, as it is closely linked to the gene. Most cases of Alzheimer's disease are thought to be sporadic and not familial. However, evidence from earlier studies suggests an important genetic contribution also in sporadic cases, where gene-environment interaction may contribute to the disease. We have determined frequencies of the GT-12 alleles in 78 Swedish and 49 British sporadic Alzheimer's disease cases and 104 healthy elderly control subjects, to investigate if the disease associates with a particular genotype in GT-12. However, no differences in allele frequencies were observed between any of the groups. (au) (26 refs.)

  18. Apnea of prematurity--perfect storm.

    Science.gov (United States)

    Di Fiore, Juliann M; Martin, Richard J; Gauda, Estelle B

    2013-11-01

    With increased survival of preterm infants as young as 23 weeks gestation, maintaining adequate respiration and corresponding oxygenation represents a clinical challenge in this unique patient cohort. Respiratory instability characterized by apnea and periodic breathing occurs in premature infants because of immature development of the respiratory network. While short respiratory pauses and apnea may be of minimal consequence if oxygenation is maintained, they can be problematic if accompanied by chronic intermittent hypoxemia. Underdevelopment of the lung and the resultant lung injury that occurs in this population concurrent with respiratory instability creates the perfect storm leading to frequent episodes of profound and recurrent hypoxemia. Chronic intermittent hypoxemia contributes to the immediate and long term co-morbidities that occur in this population. In this review we discuss the pathophysiology leading to the perfect storm, diagnostic assessment of breathing instability in this unique population and therapeutic interventions that aim to stabilize breathing without contributing to tissue injury. Copyright © 2013. Published by Elsevier B.V.

  19. LU60645GT and MA132843GT Catalogues of Lunar and Martian Impact Craters Developed Using a Crater Shape-based Interpolation Crater Detection Algorithm for Topography Data

    Science.gov (United States)

    Salamuniccar, Goran; Loncaric, Sven; Mazarico, Erwan Matias

    2012-01-01

    For Mars, 57,633 craters from the manually assembled catalogues and 72,668 additional craters identified using several crater detection algorithms (CDAs) have been merged into the MA130301GT catalogue. By contrast, for the Moon the most complete previous catalogue contains only 14,923 craters. Two recent missions provided higher-quality digital elevation maps (DEMs): SELENE (in 1/16° resolution) and Lunar Reconnaissance Orbiter (we used up to 1/512°). This was the main motivation for work on the new Crater Shape-based interpolation module, which improves previous CDA as follows: (1) it decreases the number of false-detections for the required number of true detections; (2) it improves detection capabilities for very small craters; and (3) it provides more accurate automated measurements of craters' properties. The results are: (1) LU60645GT, which is currently the most complete (up to D>=8 km) catalogue of Lunar craters; and (2) MA132843GT catalogue of Martian craters complete up to D>=2 km, which is the extension of the previous MA130301GT catalogue. As previously achieved for Mars, LU60645GT provides all properties that were provided by the previous Lunar catalogues, plus: (1) correlation between morphological descriptors from used catalogues; (2) correlation between manually assigned attributes and automated measurements; (3) average errors and their standard deviations for manually and automatically assigned attributes such as position coordinates, diameter, depth/diameter ratio, etc; and (4) a review of positional accuracy of used datasets. Additionally, surface dating could potentially be improved with the exhaustiveness of this new catalogue. The accompanying results are: (1) the possibility of comparing a large number of Lunar and Martian craters, of e.g. depth/diameter ratio and 2D profiles; (2) utilisation of a method for re-projection of datasets and catalogues, which is very useful for craters that are very close to poles; and (3) the extension of the

  20. Electromagnetic Detection of a Perfect Carpet Cloak

    Science.gov (United States)

    Shi, Xihang; Gao, Fei; Lin, Xiao; Zhang, Baile

    2015-05-01

    It has been shown that a spherical invisibility cloak originally proposed by Pendry et al. can be electromagnetically detected by shooting a charged particle through it, whose underlying mechanism stems from the asymmetry of transformation optics applied to motions of photons and charges [PRL 103, 243901 (2009)]. However, the conceptual three-dimensional invisibility cloak that exactly follows specifications of transformation optics is formidably difficult to implement, while the simplified cylindrical cloak that has been experimentally realized is inherently visible. On the other hand, the recent carpet cloak model has acquired remarkable experimental development, including a recently demonstrated full-parameter carpet cloak without any approximation in the required constitutive parameters. In this paper, we numerically investigate the electromagnetic radiation from a charged particle passing through a perfect carpet cloak and propose an experimentally verifiable model to demonstrate symmetry breaking of transformation optics.

  1. A perfect launch viewed across Banana Creek

    Science.gov (United States)

    2000-01-01

    Billows of smoke and steam surround Space Shuttle Discovery as it lifts off from Launch Pad 39A on mission STS-92 to the International Space Station. The perfect on-time liftoff occurred at 7:17 p.m. EDT, sending a crew of seven on the 100th launch in the history of the Shuttle program. Discovery carries a payload that includes the Integrated Truss Structure Z-1, first of 10 trusses that will form the backbone of the Space Station, and the third Pressurized Mating Adapter that will provide a Shuttle docking port for solar array installation on the sixth Station flight and Lab installation on the seventh Station flight. Discovery's landing is expected Oct. 22 at 2:10 p.m. EDT.

  2. The surveyors' quest for perfect alignment

    CERN Document Server

    2003-01-01

    Photogrammetry of a CMS endcap and part of the hadronic calorimeter.The structure was covered with targets photographed by digital cameras. Perfect alignment.... Although CERN's surveyors do not claim to achieve it, they are constantly striving for it and deploy all necessary means to come as close as they can. In their highly specialised field of large-scale metrology, the solution lies in geodesy and photogrammetry, both of which are based on increasingly sophisticated instruments and systems. In civil engineering, these techniques are used for non-destructive inspection of bridges, dams and other structures, while industrial applications include dimensional verification and deformation measurement in large mechanical assemblies. The same techniques also come into play for the metrology of research tools such as large telescopes and of course, particle accelerators. Particle physics laboratories are especially demanding customers, and CERN has often asked for the impossible. As a result, the alignment metro...

  3. Step-parent adoption gone wrong: GT v CT [2015] 3 ALL SA 631 (GJ ...

    African Journals Online (AJOL)

    Because of the immense impact on a child, the rescission of an adoption order has to be handled with kid gloves. In GT v CT [2015] 3 ALL SA 631 (GJ) two children had been legally adopted by their stepfather while the Child Care Act was in operation. After the implementation of the Children's Act 38 of 2005, however, ...

  4. Colletotrichine A, a new sesquiterpenoid from Colletotrichum gloeosporioides GT-7, a fungal endophyte of Uncaria rhynchophylla.

    Science.gov (United States)

    Chen, Xiao-Wei; Yang, Zhong-Duo; Sun, Jian-Hui; Song, Tong-Tong; Zhu, Bao-Ying; Zhao, Jun-Wen

    2018-04-01

    One new compound, Colletotrichine A (1), was produced by the fungal Colletotrichum gloeosporioides GT-7. The structure was established by 1D and 2D NMR spectra. Monoamine oxidase (MAO) and acetylcholinesterase (AChE) inhibitory activity of 1 was also evaluated. Compound 1 showed AChE-inhibiting activity with IC 50 value of 28 μg/mL.

  5. Comparison of Yamax pedometer and GT3X accelerometer steps in a free-living sample

    Science.gov (United States)

    Our objective was to compare steps detected by the Yamax pedometer (PEDO) versus the GT3X accelerometer (ACCEL) in free-living adults. Daily PEDO and ACCEL steps were collected from a sample of 23 overweight and obese participants (18 females; mean +/- sd: age = 52.6 +/- 8.4 yr.; body mass index = 3...

  6. Control-relevant modeling and simulation of a SOFC-GT hybrid system

    Directory of Open Access Journals (Sweden)

    Rambabu Kandepu

    2006-07-01

    Full Text Available In this paper, control-relevant models of the most important components in a SOFC-GT hybrid system are described. Dynamic simulations are performed on the overall hybrid system. The model is used to develop a simple control structure, but the simulations show that more elaborate control is needed.

  7. Control-relevant modeling and simulation of a SOFC-GT hybrid system

    OpenAIRE

    Rambabu Kandepu; Lars Imsland; Christoph Stiller; Bjarne A. Foss; Vinay Kariwala

    2006-01-01

    In this paper, control-relevant models of the most important components in a SOFC-GT hybrid system are described. Dynamic simulations are performed on the overall hybrid system. The model is used to develop a simple control structure, but the simulations show that more elaborate control is needed.

  8. Inter-Faith Reading of Perfect Man With Mystical Approach

    Directory of Open Access Journals (Sweden)

    Fatemeh Musavi

    2010-12-01

    Full Text Available The expression Insan –e kamil (perfect man is often said to have first been used by Muhyiddin ibn 'Arabi (1165 -1240AD, though the concept of the term is much older. In his theosophical teaching, the doctrine of insan e- kamil, is held a prominent place. After him two other great Sufis, Aziz Nasafi (1300AD and 'Abd al- karim ibn Ibrahim al- Jili (1366 – 1424 AD, each wrote a work on this very issue. These works are regarded as explanations of Ibn Arabi’s teachings on human perfection. In Islamic mysticism, Perfect man is the one who within their soul possesses all God's names and attributes. Thus the perfect man’s existence, reality and inner might become a clear mirror and a complete reflection of the Perfection, Beauty and Glory of the Essence of the One, so that he becomes Godlike. However, the idea of human perfectibility going back to other religions and human schools even before Islam. In Abrahimic religions there are some joint teachings that could be considered as main statements for the doctrine of Perfect Man In Jewish scriptures the notion of human creation in God's image suggests that the human being is able to be God's like and the perfection is available to him. However, Jews do not believe a perfect man. They hold that even Moses is not a perfect man. In Christianity, Although Jesus encourages his followers to be perfect like their heavenly fathers, the doctrine of original sin to be considered as an obstacle for human perfectibility.This essay examines some significant element in human perfectibility from the view points of some scholars of Judaism, Christianity and Islam and presents some similarities and differences of their view points.

  9. Inter-Faith Reading of Perfect Man With Mystical Approach

    Directory of Open Access Journals (Sweden)

    Mohammadkazem Shaker

    2011-01-01

    Full Text Available   The expression Insan –e kamil (perfect man is often said to have first been used by Muhyiddin ibn 'Arabi (1165 -1240AD, though the concept of the term is much older. In his theosophical teaching, the doctrine of insan e- kamil, is held a prominent place. After him two other great Sufis, Aziz Nasafi (1300AD and 'Abd al- karim ibn Ibrahim al- Jili (1366 – 1424 AD, each wrote a work on this very issue. These works are regarded as explanations of Ibn Arabi’s teachings on human perfection. In Islamic mysticism, Perfect man is the one who within their soul possesses all God's names and attributes. Thus the perfect man’s existence, reality and inner might become a clear mirror and a complete reflection of the Perfection, Beauty and Glory of the Essence of the One, so that he becomes Godlike. However, the idea of human perfectibility going back to other religions and human schools even before Islam. In Abrahimic religions there are some joint teachings that could be considered as main statements for the doctrine of Perfect Man In Jewish scriptures the notion of human creation in God's image suggests that the human being is able to be God's like and the perfection is available to him. However, Jews do not believe a perfect man. They hold that even Moses is not a perfect man. In Christianity, Although Jesus encourages his followers to be perfect like their heavenly fathers, the doctrine of original sin to be considered as an obstacle for human perfectibility.This essay examines some significant element in human perfectibility from the view points of some scholars of Judaism, Christianity and Islam and presents some similarities and differences of their view points.

  10. Inter-Faith Reading of Perfect Man With Mystical Approach

    Directory of Open Access Journals (Sweden)

    Shaker, M.K

    2011-01-01

    Full Text Available The expression Insan –e kamil (perfect man is often said to have first been used by Muhyiddin ibn 'Arabi (1165 -1240AD, though the concept of the term is much older. In his theosophical teaching, the doctrine of insan e- kamil, is held a prominent place. After him two other great Sufis, Aziz Nasafi (1300AD and 'Abd al- karim ibn Ibrahim al- Jili (1366 – 1424 AD, each wrote a work on this very issue. These works are regarded as explanations of Ibn Arabi’s teachings on human perfection. In Islamic mysticism, Perfect man is the one who within their soul possesses all God's names and attributes. Thus the perfect man’s existence, reality and inner might become a clear mirror and a complete reflection of the Perfection, Beauty and Glory of the Essence of the One, so that he becomes Godlike. However, the idea of human perfectibility going back to other religions and human schools even before Islam. In Abrahimic religions there are some joint teachings that could be considered as main statements for the doctrine of Perfect Man In Jewish scriptures the notion of human creation in God's image suggests that the human being is able to be God's like and the perfection is available to him. However, Jews do not believe a perfect man. They hold that even Moses is not a perfect man. In Christianity, Although Jesus encourages his followers to be perfect like their heavenly fathers, the doctrine of original sin to be considered as an obstacle for human perfectibility.This essay examines some significant element in human perfectibility from the view points of some scholars of Judaism, Christianity and Islam and presents some similarities and differences of their view points.

  11. Characteristic analysis of rotor dynamics and experiments of active magnetic bearing for HTR-10GT

    International Nuclear Information System (INIS)

    Yang Guojun; Xu Yang; Shi Zhengang; Gu Huidong

    2005-01-01

    A 10 MW high-temperature gas-cooled reactor (HTR-10) was constructed by the Institute of Nuclear and New Energy Technology (INET) at Tsinghua University of China. The helium turbine and generator system of 10 MW high temperature gas-cooled reactor (HTR-10GT) is the second phase for the HTR-10 project. It is to set up a direct helium cycle to replace the current steam cycle. The active magnetic bearing (AMB) instead of ordinary mechanical bearing was chosen to support the rotor in the HTR-10GT. This rotor is vertically mounted to hold the turbine machine, compressors and the power generator together. The rotor's length is 7 m, its weight is about 1500 kg and the rotating speed is 15000 r/min. The structure of the rotor is so complicated that dynamic analysis of the rotor becomes difficult. One of the challenging problems is to exceed natural frequencies with enough stability and safety during reactor start up, power change and shutdown. The dynamic analysis of the rotor is the base for the design of control system. It is important for the rotor to exceed critical speeds. Some kinds of software and methods, such as MSC.Marc, Ansys, and the Transfer Matrix Method, are compared to fully analyze rotor dynamics characteristic in this paper. The modal analysis has been done for the HTR-10GT rotor. MSC.Marc was finally selected to analyze the vibration mode and the natural frequency of the rotor. The effects of AMB stiffness on the critical speeds of the rotor were studied. The design characteristics of the AMB control system for the HTR-10GT were studied and the related experiment to exceed natural frequencies was introduced. The experimental results demonstrate the system functions and validate the control scheme, which will be used in the HTR-10GT project. (authors)

  12. Analgesic effect of GT-0198, a structurally novel glycine transporter 2 inhibitor, in a mouse model of neuropathic pain

    Directory of Open Access Journals (Sweden)

    Yu Omori

    2015-03-01

    Full Text Available This study was conducted to identify the characteristic pharmacological features of GT-0198 that is phenoxymethylbenzamide derivatives. GT-0198 inhibited the function of glycine transporter 2 (GlyT2 in human GlyT2-expressing HEK293 cells and did not bind various major transporters or receptors of neurotransmitters in a competitive manner. Thus, GT-0198 is considered to be a comparatively selective GlyT2 inhibitor. Intravenous, oral, and intrathecal injections of GT-0198 decreased the pain-related response in a model of neuropathic pain with partial sciatic nerve ligation. This result suggests that GT-0198 has an analgesic effect. The analgesic effect of GT-0198 was abolished by the intrathecal injection of strychnine, a glycine receptor antagonist. Therefore, GT-0198 is considered to exhibit its analgesic effect via the activation of a glycine receptor by glycine following presynaptic GlyT2 inhibition in the spinal cord. In summary, GT-0198 is a structurally novel GlyT2 inhibitor bearing a phenoxymethylbenzamide moiety with in vivo efficacy in behavioral models of neuropathic pain.

  13. Structural Characterization of the Foliated-Layered Gabbro Transition in Wadi Tayin of the Samail Ophiolite, Oman; Oman Drilling Project Holes GT1A and GT2A

    Science.gov (United States)

    Deans, J. R.; Crispini, L.; Cheadle, M. J.; Harris, M.; Kelemen, P. B.; Teagle, D. A. H.; Matter, J. M.; Takazawa, E.; Coggon, J. A.

    2017-12-01

    Oman Drilling Project Holes GT1A and GT2A were drilled into the Wadi Tayin massif, Samail ophiolite and both recovered ca. 400 m of continuous core through a section of the layered gabbros and the foliated-layered gabbro transition. Hole GT1A is cut by a discrete fault system including localized thin ultracataclastic fault zones. Hole GT2A is cut by a wider zone of brittle deformation and incipient brecciation. Here we report the structural history of the gabbros reflecting formation at the ridge to later obduction. Magmatic and high temperature history- 1) Both cores exhibit a pervasive, commonly well-defined magmatic foliation delineated by plagioclase, olivine and in places clinopyroxene. Minor magmatic deformation is present. 2) The dip of the magmatic foliation varies cyclically, gradually changing dip by 30o from gentle to moderate over a 50 m wavelength. 3) Layering is present throughout both cores, is defined by changes in mode and grain size ranging in thickness from 2 cm to 3 m and is commonly sub-parallel to the foliation. 4) There are no high temperature crystal-plastic shear zones in the core. Key observations include: no simple, systematic shallowing of dip with depth across the foliated-layered gabbro transition and layering is continuous across this transition. Cyclic variation of magmatic foliation dip most likely reflects the process of plate separation at the ridge axis. Near-axis faulting- i) On or near-axis structures consist of epidote-amphibole bearing hydraulic breccias and some zones of intense cataclasis with intensely deformed epidote and seams of clay and chlorite accompanied by syntectonic alteration of the wall rock. Early veins are filled with amphibole, chlorite, epidote, and anhydrite. ii) The deformation ranges from brittle-ductile, causing local deflection of the magmatic foliation, to brittle offset of the foliation and core and mantle structures in anhydrite veins. iii) The prevalent sense of shear is normal and slickenfibers

  14. Feasibility study for SOFC-GT hybrid locomotive power: Part I. Development of a dynamic 3.5 MW SOFC-GT FORTRAN model

    OpenAIRE

    Martinez, AS; Brouwer, J; Samuelsen, GS

    2012-01-01

    This work presents the development of a dynamic SOFC-GT hybrid system model applied to a long-haul freight locomotive in operation. Given the expectations of the rail industry, the model is used to develop a preliminary analysis of the proposed system's operational capability on conventional diesel fuel as well as natural gas and hydrogen as potential fuels in the future. It is found that operation of the system on all three of these fuels is feasible with favorable efficiencies and reasonabl...

  15. Modern problems of perfection of elite light athletic sportsmen’s technical skillfulness perfection

    Directory of Open Access Journals (Sweden)

    A.V. Kolot

    2016-04-01

    Full Text Available Purpose: perfection of elite sportsmen’s technical skillfulness in competition kinds of light athletic. Material: the data of more than 60 literature sources were systemized. Expert questioning of 36 coaches, having experience of work with elite sportsmen, was carried out; documents of training process planning were analyzed as well as sportsmen’s diaries (n=244. Results: we have presented main principles of sportsmen’s technical skillfulness perfection and elucidated characteristics of technical training methodic. We have determined main priorities of technical training building for light athletes at every stage of many years’ perfection. Dynamic of competition practice volume has been found as well as main requirements to selection of training means of technical orientation. The data of bio-mechanical criteria of sportsmen’s technical skillfulness assessment have been supplemented. Conclusions: effectiveness of sportsmen’s training methodic is determined by realization of previous stages’ technical potential in final competition results. It can be achieved by determination of means of and methods of different orientation rational correlation.

  16. Modern problems of perfection of elite light athletic sportsmen’s technical skillfulness perfection

    Directory of Open Access Journals (Sweden)

    Kolot A.V.

    2016-02-01

    Full Text Available Purpose: perfection of elite sportsmen’s technical skillfulness in competition kinds of light athletic. Material: the data of more than 60 literature sources were systemized. Expert questioning of 36 coaches, having experience of work with elite sportsmen, was carried out; documents of training process planning were analyzed as well as sportsmen’s diaries (n=244. Results: we have presented main principles of sportsmen’s technical skillfulness perfection and elucidated characteristics of technical training methodic. We have determined main priorities of technical training building for light athletes at every stage of many years’ perfection. Dynamic of competition practice volume has been found as well as main requirements to selection of training means of technical orientation. The data of bio-mechanical criteria of sportsmen’s technical skillfulness assessment have been supplemented. Conclusions: effectiveness of sportsmen’s training methodic is determined by realization of previous stages’ technical potential in final competition results. It can be achieved by determination of means of and methods of different orientation rational correlation.

  17. The swimming of a perfect deforming helix

    Science.gov (United States)

    Koens, Lyndon; Zhang, Hang; Mourran, Ahmed; Lauga, Eric

    2017-11-01

    Many bacteria rotate helical flagellar filaments in order to swim. When at rest or rotated counter-clockwise these flagella are left handed helices but they undergo polymorphic transformations to right-handed helices when the motor is reversed. These helical deformations themselves can generate motion, with for example Rhodobacter sphaeroides using the polymorphic transformation of the flagellum to generate rotation, or Spiroplasma propagating a change of helix handedness across its body's length to generate forward motion. Recent experiments reported on an artificial helical microswimmer generating motion without a propagating change in handedness. Made of a temperature sensitive gel, these swimmers moved by changing the dimensions of the helix in a non-reciprocal way. Inspired by these results and helix's ubiquitous presence in the bacterial world, we investigate how a deforming helix moves within a viscous fluid. Maintaining a single handedness along its entire length, we discuss how a perfect deforming helix can create a non-reciprocal swimming stroke, identify its principle directions of motion, and calculate the swimming kinematics asymptotically.

  18. Perfect crystal interferometer and its applications

    Energy Technology Data Exchange (ETDEWEB)

    Hasegawa, Yuji [Atominstitut der Oesterreichischen Universitaeten, Vienna (Austria)

    1996-08-01

    The interferometry with angstrom scale wavelength has developed steadily, and various types of interferometers have been investigated. Among them, LLL interferometers are widely used. The first neutron interferometry was achieved in 1962 by Maier-Leibnitz et al. A new type of neutron interferometers was constructed with a perfect crystal, and experimentally performed in 1974 by Rauch et al. The precise measurements with LLL neutron interferometers were performed on scattering length, gravitational effect, coherence, Fizeau effects, spin superposition, complementarity, and post-selection effects. Since the early stage of quantum physics, the double-slit experiment has served as the example of the epistemologically strange features of quantum phenomena, and its course of study is described. The time-delayed interferometry with nuclear resonant scattering of synchrotron radiation and phase transfer in time-delayed interferometry with nuclear resonant scattering were experimented, and are briefly reported. A geometric phase factor was derived for a split beam experiment as an example of cyclic evolution. The geometric phase was observed with a two-loop neutron interferometer. All the experimental results showed complete agreement with the theoretical treatment. (K.I.)

  19. Memory and Perfection in Ferroelastic Inclusion Compounds

    International Nuclear Information System (INIS)

    Hollingsworth, M.; Peterson, M.; Rush, J.; Brown, M.; Abel, M.; Black, A.; Dudley, M.; Raghothamachar, B.; Werner-Zwanziger, U.

    2005-01-01

    In a series of ferroelastic urea inclusion compounds (UICs), in which domain reorientation occurs upon application of an external anisotropic force, introduction of a relaxive impurity that disrupts a specific hydrogen-bonding network transforms a plastic (irreversible) domain-switching process into one that exhibits a striking memory effect and 'rubber-like behavior', a form of pseudoelasticity. As expected for a highly cooperative process, the ferroelastic response to the impurity concentration exhibits a critical threshold. Through synchrotron white-beam X-ray topography (SWBXT) of crystals under stress, videomicroscopy of spontaneous repair during crystal growth, acoustomechanical relaxation of daughter domains, kinetic measurements of spontaneous domain reversion, and solid-state 2 H NMR of labeled guests, this work shows how relaxive impurities lower the barrier to domain switching and how differences in perfection between mother and daughter domains provide the driving force for the memory effects. Although the interfacial effects implicated here are different from the volume effects that operate in certain shape memory materials, the twinning and defect phenomena responsible for the rubber-like behavior and memory effects should be generally applicable to domain switching in ferroelastic and ferroelectric crystals and to other solid-state processes

  20. Natural death and the work of perfection.

    Science.gov (United States)

    Young, Alexey

    1998-08-01

    The historic or traditional Christian view of pain (suffering) and death, especially as preserved by the Christians East (i.e., the Orthodox), is radically opposed to the modern secular obsession with avoidance of pain. Everything about this life has its goal or aim in a mystical reality, the Kingdom of Heaven, for which earthly life is a preparation. While neither illness nor health are seen as ends in themselves, both are viewed as proceeding from the will of God for our benefit and have no ultimate meaning or purpose outside of eternal life. Death may be a relief or an ending of suffering, but in itself it is not "good" but evil. Because they are the embodiment of lived theology, saints' lives can be a sure guide to understanding how to die as a traditional Christian. To illustrate this, I have chosen some examples from the lives of relatively recent saints. I myself am from the Russian Orthodox spiritual tradition, so all but one of my examples come from pre-Revolutionary Russia. The question is not so much whether or not a traditional Christian can countenance physician-assisted suicide, but rather, what is the meaning or purpose of pain and suffering in general. Is it part of the "work of perfection" required of those who wish to enter the Kingdom of Heaven and therefore not to be completely denied?

  1. Overview of Hole GT2A: Drilling middle gabbro in Wadi Tayin massif, Oman ophiolite

    Science.gov (United States)

    Takazawa, E.; Kelemen, P. B.; Teagle, D. A. H.; Coggon, J. A.; Harris, M.; Matter, J. M.; Michibayashi, K.

    2017-12-01

    Hole GT2A (UTM: 40Q 655960.7E / 2529193.5N) was drilled by the Oman Drilling Project (OmDP) into Wadi Gideah of Wadi Tayin massif in the Samail ophiolite, Oman. OmDP is an international collaboration supported by the International Continental Scientific Drilling Program, the Deep Carbon Observatory, NSF, IODP, JAMSTEC, and the European, Japanese, German and Swiss Science Foundations, with in-kind support in Oman from the Ministry of Regional Municipalities and Water Resources, Public Authority of Mining, Sultan Qaboos University, and the German University of Technology. Hole GT2A was diamond cored in 25 Dec 2016 to 18 Jan 2017 to a total depth of 406.77 m. The outer surfaces of the cores were imaged and described on site before being curated, boxed and shipped to the IODP drill ship Chikyu, where they underwent comprehensive visual and instrumental analysis. 33 shipboard scientists were divided into six teams (Igneous, Alteration, Structural, Geochem, Physical Properties, Paleomag) to describe and analyze the cores. Hole GT2A drilled through the transition between foliated and layered gabbro. The transition zone occurs between 50 and 150 m curation corrected depth (CCD). The top 50 m of Hole GT2A is foliated gabbro whereas the bottom 250 m consists of layered gabbro. Brittle fracture is observed throughout the core. Intensity of alteration vein decreases from the top to the bottom of the hole. On the basis of changes in grain size and/or modal abundance and/or appearance/disappearance of igneous primary mineral(s) five lithological units are defined in Hole GT2A (Unit I to V). The uppermost part of Hole GT2A (Unit I) is dominated by fine-grained granular olivine gabbro intercalated with less dominant medium-grained granular olivine gabbro and rare coarse-grained varitextured gabbro. The lower part of the Hole (Units II, III and V) is dominated by medium-grained olivine gabbro, olivine melagabbro and olivine-bearing gabbro. Modally-graded rhythmic layering with

  2. An essential GT motif in the lamin A promoter mediates activation by CREB-binding protein

    International Nuclear Information System (INIS)

    Janaki Ramaiah, M.; Parnaik, Veena K.

    2006-01-01

    Lamin A is an important component of nuclear architecture in mammalian cells. Mutations in the human lamin A gene lead to highly degenerative disorders that affect specific tissues. In studies directed towards understanding the mode of regulation of the lamin A promoter, we have identified an essential GT motif at -55 position by reporter gene assays and mutational analysis. Binding of this sequence to Sp transcription factors has been observed in electrophoretic mobility shift assays and by chromatin immunoprecipitation studies. Further functional analysis by co-expression of recombinant proteins and ChIP assays has shown an important regulatory role for CREB-binding protein in promoter activation, which is mediated by the GT motif

  3. HTGR-GT primary coolant transient resulting from postulated turbine deblading

    International Nuclear Information System (INIS)

    Cadwallader, G.J.; Deremer, R.K.

    1980-11-01

    The turbomachine is located within the primary coolant system of a nuclear closed cycle gas turbine plant (HTGR-GT). The deblading of the turbine can cause a rapid pressure equilibration transient that generates significant loads on other components in the system. Prediction of and design for this transient are important aspects of assuring the safety of the HTGR-GT. This paper describes the adaptation and use of the RATSAM program to analyze the rapid fluid transient throughout the primary coolant system during a spectrum of turbine deblading events. Included are discussions of (1) specific modifications and improvements to the basic RATSAM program, which is also briefly described; (2) typical results showing the expansion wave moving upstream from the debladed turbine through the primary coolant system; and (3) the effect on the transient results of different plenum volumes, flow resistances, times to deblade, and geometries that can choke the flow

  4. Actual characteristics study on HTR-10GT coupling with direct gas turbine cycle

    International Nuclear Information System (INIS)

    Peng Xuechuang; Zhu Shutang; Wang Jie

    2005-01-01

    HTR-10GT is a testing project coupling the reactor HTR-10 with direct gas turbine cycle. Its thermal cycle can be taken as a closed, recuperated and inter-cooled Brayton cycle. The present study is focused on the thermal cycle performance of HTR-10GT under practical conditions of leakage, pressure losses, etc.. Through thermodynamic analysis, the expression of cycle efficiency for actual thermal cycle is derived. By establishing a physical model with friction loss and leakage, a set of governing equation are constructed based on some reasonable assumptions. The results of actual cycle efficiency have been calculated for different leakage amount at different locations while the effects of leakage under different power level have also been calculated and analyzed. (authors)

  5. DISTORSI KAPASITAS PERDAGANGAN INTER-REGIONAL IMT-GT Kasus Provinsi Terpilih di Sumatera Indonesia

    Directory of Open Access Journals (Sweden)

    Benito Rio Avianto

    2015-06-01

    Full Text Available The objective of the paper was to understand the impact of sub regional economic cooperation, known as the Indonesia-Malaysia-Thailand Growth Triangle (IMT-GT, on trade sector in Indonesia. The approach of research based on export macro information by provinces and commodities. The method used in the analytical framework was a fixed effect method. The regional study covered Nanggroe Aceh Darussalam, North Sumatera, West Sumatera, and Riau provinces, and the commodities involved CPO, coffee and rubber, with 1990-2008 data series. Based on pooled regression, there was a significant impact on export from the four provinces to Malaysia and Thailand for all based years. One might focus on commodity level that, in fact, CPO was the only one commodity that had a significant impact within the IMTGT region. In addition, Thai Bath and Malaysian Ringgit, with respect to GDP for both countries, had significant influenced on export, especially after the IMT-GT endorsed.

  6. The Vitamin E Analog Gamma-Tocotrienol (GT3 and Statins Synergistically Up-Regulate Endothelial Thrombomodulin (TM

    Directory of Open Access Journals (Sweden)

    Rupak Pathak

    2016-11-01

    Full Text Available Statins; a class of routinely prescribed cholesterol-lowering drugs; inhibit 3-hydroxy-3-methylglutaryl-coenzymeA reductase (HMGCR and strongly induce endothelial thrombomodulin (TM; which is known to have anti-inflammatory; anti-coagulation; anti-oxidant; and radioprotective properties. However; high-dose toxicity limits the clinical use of statins. The vitamin E family member gamma-tocotrienol (GT3 also suppresses HMGCR activity and induces TM expression without causing significant adverse side effects; even at high concentrations. To investigate the synergistic effect of statins and GT3 on TM; a low dose of atorvastatin and GT3 was used to treat human primary endothelial cells. Protein-level TM expression was measured by flow cytometry. TM functional activity was determined by activated protein C (APC generation assay. Expression of Kruppel-like factor 2 (KLF2, one of the key transcription factors of TM, was measured by quantitative reverse transcription polymerase chain reaction (qRT-PCR. TM expression increased in a dose-dependent manner after both atorvastatin and GT3 treatment. A combined treatment of a low-dose of atorvastatin and GT3 synergistically up-regulated TM expression and functional activity. Finally; atorvastatin and GT3 synergistically increased KLF2 expression. These findings suggest that combined treatment of statins with GT3 may provide significant health benefits in treating a number of pathophysiological conditions; including inflammatory and cardiovascular diseases.

  7. Development of a perfect prognosis probabilistic model for ...

    Indian Academy of Sciences (India)

    A prediction model based on the perfect prognosis method was developed to predict the probability of lightning and probable time of its occurrence over the south-east Indian region. In the perfect prognosis method, statistical relationships are established using past observed data. For real time applications, the predictors ...

  8. A cross-linguistic discourse analysis of the perfect

    NARCIS (Netherlands)

    Swart, Henriëtte de

    2007-01-01

    Since Reichenbach (1947), the Present Perfect has been discussed in relation to the Simple Past. The Reichenbachian characterization E-R,S has led to the view that the English Present Perfect, with its restrictions on modification by time adverbials and its resistance to narrative structure is the

  9. Design, Operation and Control Modelling of SOFC/GT Hybrid Systems

    OpenAIRE

    Stiller, Christoph

    2006-01-01

    This thesis focuses on modelling-based design, operation and control of solid oxide fuel cell (SOFC) and gas turbine (GT) hybrid systems. Fuel cells are a promising approach to high-efficiency power generation, as they directly convert chemical energy to electric work. High-temperature fuel cells such as the SOFC can be integrated in gas turbine processes, which further increases the electrical efficiency to values up to 70%. However, there are a number of obstacles for safe operation of such...

  10. Power unit with GT-MHR reactor plant for electricity production and district heating

    International Nuclear Information System (INIS)

    Kiryushin, A.L.; Kodochigov, N.G.; Kuzavkov, N.G.; Golovko, V.F.

    2000-01-01

    Modular helium reactor with the gas turbine (GT-MHR) is a perspective power reactor plant for the next century. The project reactor is based on experience of operation more than 50 gas-cooled reactors on carbon dioxide and helium, and also on subsequent achievements in the field of realization direct gas turbine Brayton cycle. To the beginning of 90 years, achievements in technology of gas turbines, highly effective recuperators and magnetic bearings made it possible to start development of the reactor plant project combining a safe modular gas cooled reactor and a power conversion system, realizing the highly effective Brayton cycle. The conceptual project of the commercial GT-MHR reactor plant fulfilled in 1997 by joint efforts of international firms, combines a safe modular reactor with an annular active core of prismatic fuel blocks and a power conversion system with direct gas turbine cycle. The efficiency of GT-MHR gas turbine cycle at level of about 48% makes it competitive in the electricity production market in comparison with any fossil or nuclear power stations

  11. Microsatellite D21D210 (GT-12) allele frequencies in sporadic Alzheimer`s disease

    Energy Technology Data Exchange (ETDEWEB)

    Lannfelt, L; Lilius, L; Viitanen, M; Winblad, B; Basun, H [Huddinge Hospital, Karolinska Institute, Dept. of Geriatric Medicine, (Sweden); Houlden, H; Rossor, M [St. Mary` s Hospital, Dept. of Neurology, Medical School, London (United Kingdom); Hardy, J [University of South Florida, Suncoast Alzheimer` s Disease Research Labs, Department of Psychiatry, Tampa (United States)

    1995-02-01

    Four disease-causing mutations have so far been described in the amyloid precursor protein gene on chromosome 21 in familial early-onset Alzheimer`s disease. Linkage analysis with a fourteen-allele microsatellite at D21S210 named GT-12 has proven useful in the elucidation of amyloid presursor protein gene involvement in Alzheimer`s disease families, as it is closely linked to the gene. Most cases of Alzheimer`s disease are thought to be sporadic and not familial. However, evidence from earlier studies suggests an important genetic contribution also in sporadic cases, where gene-environment interaction may contribute to the disease. We have determined frequencies of the GT-12 alleles in 78 Swedish and 49 British sporadic Alzheimer`s disease cases and 104 healthy elderly control subjects, to investigate if the disease associates with a particular genotype in GT-12. However, no differences in allele frequencies were observed between any of the groups. (au) (26 refs.).

  12. Lattice fluid dynamics from perfect discretizations of continuum flows

    International Nuclear Information System (INIS)

    Katz, E.; Wiese, U.

    1998-01-01

    We use renormalization group methods to derive equations of motion for large scale variables in fluid dynamics. The large scale variables are averages of the underlying continuum variables over cubic volumes and naturally exist on a lattice. The resulting lattice dynamics represents a perfect discretization of continuum physics, i.e., grid artifacts are completely eliminated. Perfect equations of motion are derived for static, slow flows of incompressible, viscous fluids. For Hagen-Poiseuille flow in a channel with a square cross section the equations reduce to a perfect discretization of the Poisson equation for the velocity field with Dirichlet boundary conditions. The perfect large scale Poisson equation is used in a numerical simulation and is shown to represent the continuum flow exactly. For nonsquare cross sections one can use a numerical iterative procedure to derive flow equations that are approximately perfect. copyright 1998 The American Physical Society

  13. HTGR-GT closed-cycle gas turbine: a plant concept with inherent cogeneration (power plus heat production) capability

    International Nuclear Information System (INIS)

    McDonald, C.F.

    1980-04-01

    The high-grade sensible heat rejection characteristic of the high-temperature gas-cooled reactor-gas turbine (HTGR-GT) plant is ideally suited to cogeneration. Cogeneration in this nuclear closed-cycle plant could include (1) bottoming Rankine cycle, (2) hot water or process steam production, (3) desalination, and (4) urban and industrial district heating. This paper discusses the HTGR-GT plant thermodynamic cycles, design features, and potential applications for the cogeneration operation modes. This paper concludes that the HTGR-GT plant, which can potentially approach a 50% overall efficiency in a combined cycle mode, can significantly aid national energy goals, particularly resource conservation

  14. Revisiting the TALE repeat.

    Science.gov (United States)

    Deng, Dong; Yan, Chuangye; Wu, Jianping; Pan, Xiaojing; Yan, Nieng

    2014-04-01

    Transcription activator-like (TAL) effectors specifically bind to double stranded (ds) DNA through a central domain of tandem repeats. Each TAL effector (TALE) repeat comprises 33-35 amino acids and recognizes one specific DNA base through a highly variable residue at a fixed position in the repeat. Structural studies have revealed the molecular basis of DNA recognition by TALE repeats. Examination of the overall structure reveals that the basic building block of TALE protein, namely a helical hairpin, is one-helix shifted from the previously defined TALE motif. Here we wish to suggest a structure-based re-demarcation of the TALE repeat which starts with the residues that bind to the DNA backbone phosphate and concludes with the base-recognition hyper-variable residue. This new numbering system is consistent with the α-solenoid superfamily to which TALE belongs, and reflects the structural integrity of TAL effectors. In addition, it confers integral number of TALE repeats that matches the number of bound DNA bases. We then present fifteen crystal structures of engineered dHax3 variants in complex with target DNA molecules, which elucidate the structural basis for the recognition of bases adenine (A) and guanine (G) by reported or uncharacterized TALE codes. Finally, we analyzed the sequence-structure correlation of the amino acid residues within a TALE repeat. The structural analyses reported here may advance the mechanistic understanding of TALE proteins and facilitate the design of TALEN with improved affinity and specificity.

  15. Reconfigurable multiport EPON repeater

    Science.gov (United States)

    Oishi, Masayuki; Inohara, Ryo; Agata, Akira; Horiuchi, Yukio

    2009-11-01

    An extended reach EPON repeater is one of the solutions to effectively expand FTTH service areas. In this paper, we propose a reconfigurable multi-port EPON repeater for effective accommodation of multiple ODNs with a single OLT line card. The proposed repeater, which has multi-ports in both OLT and ODN sides, consists of TRs, BTRs with the CDR function and a reconfigurable electrical matrix switch, can accommodate multiple ODNs to a single OLT line card by controlling the connection of the matrix switch. Although conventional EPON repeaters require full OLT line cards to accommodate subscribers from the initial installation stage, the proposed repeater can dramatically reduce the number of required line cards especially when the number of subscribers is less than a half of the maximum registerable users per OLT. Numerical calculation results show that the extended reach EPON system with the proposed EPON repeater can save 17.5% of the initial installation cost compared with a conventional repeater, and can be less expensive than conventional systems up to the maximum subscribers especially when the percentage of ODNs in lightly-populated areas is higher.

  16. Quantum repeated games revisited

    International Nuclear Information System (INIS)

    Frąckiewicz, Piotr

    2012-01-01

    We present a scheme for playing quantum repeated 2 × 2 games based on Marinatto and Weber’s approach to quantum games. As a potential application, we study the twice repeated Prisoner’s Dilemma game. We show that results not available in the classical game can be obtained when the game is played in the quantum way. Before we present our idea, we comment on the previous scheme of playing quantum repeated games proposed by Iqbal and Toor. We point out the drawbacks that make their results unacceptable. (paper)

  17. The evaluation of MCI, MI, PMI and GT on both genders with different age and dental status.

    Science.gov (United States)

    Bozdag, G; Sener, S

    2015-01-01

    The aim of this study was to measure the mandibular cortical index (MCI), mental index (MI), panoramic mandibular index (PMI) and cortical bone thickness in the zone of the gonial angle (GT) in panoramic radiographies from a large sample of males and females and to determine how they relate to patients' age, gender and dental status. 910 panoramic radiographs were obtained and grouped into age, dental status and gender. The MCI, MI, PMI and GT were analysed. Remarkable differences were observed for MCI and GT regarding gender, age groups and dental status on both sides (p PMI in females, dental status had an effect on the MI and PMI in males (p PMI (p PMI and MI measurements. The effects of age and tooth loss in the GT and MCI measurements are similar, and these indices can be accepted as more reliable in studies including both genders.

  18. Scheme for achieving coherent perfect absorption by anisotropic metamaterials

    KAUST Repository

    Zhang, Xiujuan

    2017-02-22

    We propose a unified scheme to achieve coherent perfect absorption of electromagnetic waves by anisotropic metamaterials. The scheme describes the condition on perfect absorption and offers an inverse design route based on effective medium theory in conjunction with retrieval method to determine practical metamaterial absorbers. The scheme is scalable to frequencies and applicable to various incident angles. Numerical simulations show that perfect absorption is achieved in the designed absorbers over a wide range of incident angles, verifying the scheme. By integrating these absorbers, we further propose an absorber to absorb energy from two coherent point sources.

  19. Two-perfect fluid interpretation of an energy tensor

    International Nuclear Information System (INIS)

    Ferrando, J.J.; Morales, J.A.; Portilla, M.

    1990-01-01

    There are many topics in General Relativity where matter is represented by a mixture of two fluids. In fact, some astrophysical and cosmological situations need to be described by an energy tensor made up of the sum of two or more perfect fluids rather than that with only one. The paper contains the necessary and sufficient conditions for a given energy tensor to be interpreted as a sum of two perfect fluids. Given a tensor of this class, the decomposition in two perfect fluids (which is determined up to a couple of real functions) is obtained

  20. Replication study of STAT4 rs7574865 G/T polymorphism and risk of rheumatoid arthritis in a Chinese population.

    Science.gov (United States)

    Shen, Li; Liu, Ruiping; Zhang, Hui; Huang, Yong; Sun, Rongbin; Tang, Peifu

    2013-09-10

    Rheumatoid arthritis (RA) and ankylosing spondylitis (AS) are common systemic autoimmune diseases with genetic and environmental predisposing factors. Signal transducer and activator of transcription 4 (STAT4) transmits signals induced by interleukin-12, interleukin-23 and interferon-γ, which are key cytokines and play important roles in the development of autoimmune diseases. Previous studies confirmed the STAT4 rs7574865 G/T locus to be associated with RA. Thus we conducted a replication study to investigate STAT4 rs7574865 G/T polymorphism and RA/AS susceptibility in a Chinese population. We studied STAT4 rs7574865 G/T gene polymorphism in 520 patients with RA, 100 AS patients and 520 controls in a Chinese population. Genotyping was done using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). When the STAT4 rs7574865 GG homozygote genotype was used as the reference group, the GT or GT/TT genotypes were associated with the risk for RA. After stratification analyses, a significantly increased risk for RA associated with the STAT4 rs7574865 GT genotype was evident among the rheumatoid factor (RF)-positive patients, patients with higher erythrocyte sedimentation rate (ESR) level and patients with higher RA disease activity score (DAS28) compared with the STAT4 rs7574865 GG genotype. A significantly increased risk for RA associated with the STAT4 rs7574865 TT genotype was evident among older patients and RF-negative patients compared with the STAT4 rs7574865 GG genotype. STAT4 rs7574865 G/T was not associated with susceptibility to AS. This replication study confirmed that STAT4 rs7574865 G/T polymorphism was associated with the risk of RA. STAT4 polymorphisms are associated with rheumatoid arthritis risk. Copyright © 2013 Elsevier B.V. All rights reserved.

  1. Repeat migration and disappointment.

    Science.gov (United States)

    Grant, E K; Vanderkamp, J

    1986-01-01

    This article investigates the determinants of repeat migration among the 44 regions of Canada, using information from a large micro-database which spans the period 1968 to 1971. The explanation of repeat migration probabilities is a difficult task, and this attempt is only partly successful. May of the explanatory variables are not significant, and the overall explanatory power of the equations is not high. In the area of personal characteristics, the variables related to age, sex, and marital status are generally significant and with expected signs. The distance variable has a strongly positive effect on onward move probabilities. Variables related to prior migration experience have an important impact that differs between return and onward probabilities. In particular, the occurrence of prior moves has a striking effect on the probability of onward migration. The variable representing disappointment, or relative success of the initial move, plays a significant role in explaining repeat migration probabilities. The disappointment variable represents the ratio of actural versus expected wage income in the year after the initial move, and its effect on both repeat migration probabilities is always negative and almost always highly significant. The repeat probabilities diminish after a year's stay in the destination region, but disappointment in the most recent year still has a bearing on the delayed repeat probabilities. While the quantitative impact of the disappointment variable is not large, it is difficult to draw comparisons since similar estimates are not available elsewhere.

  2. The Ideology of the Perfect Dictionary: How Efficient Can a ...

    African Journals Online (AJOL)

    friendly material which will improve both their fluency in and understanding of the target language, and embed acquired lexis in their long-term memory. Lexicographers, in their search for perfection and in compliance with users' wishes, are ...

  3. Perfect 3-colorings of the cubic graphs of order 10

    Directory of Open Access Journals (Sweden)

    Mehdi Alaeiyan

    2017-10-01

    Full Text Available Perfect coloring is a generalization of the notion of completely regular codes, given by Delsarte. A perfect m-coloring of a graph G with m colors is a partition of the vertex set of G into m parts A_1, A_2, ..., A_m such that, for all $ i,j \\in \\lbrace 1, ... , m \\rbrace $, every vertex of A_i is adjacent to the same number of vertices, namely, a_{ij} vertices, of A_j. The matrix $A=(a_{ij}_{i,j\\in \\lbrace 1,... ,m\\rbrace }$, is called the parameter matrix. We study the perfect 3-colorings (also known as the equitable partitions into three parts of the cubic graphs of order 10. In particular, we classify all the realizable parameter matrices of perfect 3-colorings for the cubic graphs of order 10.

  4. Perfect imaging with positive refraction in three dimensions

    International Nuclear Information System (INIS)

    Leonhardt, Ulf; Philbin, Thomas G.

    2010-01-01

    Maxwell's fish eye has been known to be a perfect lens within the validity range of ray optics since 1854. Solving Maxwell's equations, we show that the fish-eye lens in three dimensions has unlimited resolution for electromagnetic waves.

  5. Simulation of MILD combustion using Perfectly Stirred Reactor model

    KAUST Repository

    Chen, Z.; Vanteru, Mahendra Reddy; Ruan, S.; Doan, N. A K; Roberts, William L.; Swaminathan, N.

    2016-01-01

    A simple model based on a Perfectly Stirred Reactor (PSR) is proposed for moderate or intense low-oxygen dilution (MILD) combustion. The PSR calculation is performed covering the entire flammability range and the tabulated chemistry approach is used

  6. Scheme for achieving coherent perfect absorption by anisotropic metamaterials

    KAUST Repository

    Zhang, Xiujuan; Wu, Ying

    2017-01-01

    in conjunction with retrieval method to determine practical metamaterial absorbers. The scheme is scalable to frequencies and applicable to various incident angles. Numerical simulations show that perfect absorption is achieved in the designed absorbers over a

  7. FSV experience in support of the GT-MHR reactor physics, fuel performance, and graphite

    International Nuclear Information System (INIS)

    Baxter, A.M.; McEachern, D.; Hanson, D.L.; Vollman, R.E.

    1994-11-01

    The Fort St. Vrain (FSV) power plant was the most recent operating graphite-moderated, helium-cooled nuclear power plant in the United States. Many similarities exist between the FSV design and the current design of the GT-MHR. Both designs use graphite as the basic building blocks of the core, as structural material, in the reflectors, and as a neutron moderator. Both designs use hexagonal fuel elements containing cylindrical fuel rods with coated fuel particles. Helium is the coolant and the power densities vary by less than 5%. Since material and geometric properties of the GT-MHR core am very similar to the FSV core, it is logical to draw upon the FSV experience in support of the GT-MHR design. In the Physics area, testing at FSV during the first three cycles of operation has confirmed that the calculational models used for the core design were very successful in predicting the core nuclear performance from initial cold criticality through power operation and refueling. There was excellent agreement between predicted and measured initial core criticality and control rod positions during startup. Measured axial flux distributions were within 5% of the predicted value at the peak. The isothermal temperature coefficient at zero power was in agreement within 3%, and even the calculated temperature defect over the whole operating range for cycle 3 was within 8% of the measured defect. In the Fuel Performance area, fuel particle coating performance, and fission gas release predictions and an overall plateout analysis were performed for decommissioning purposes. A comparison between predicted and measured fission gas release histories of Kr-85m and Xe-138 and a similar comparison with specific circulator plateout data indicated good agreement between prediction and measured data. Only I-131 plateout data was overpredicted, while Cs-137 data was underpredicted

  8. Design of a SOFC/GT/SCs hybrid power system to supply a rural isolated microgrid

    International Nuclear Information System (INIS)

    Camblong, Haritza; Baudoin, Sylvain; Vechiu, Ionel; Etxeberria, Aitor

    2016-01-01

    Highlights: • A novel SOFC/GT/SCs HPS is connected to a rural microgrid through a 3LNPC inverter. • An operating strategy that maintains the SOFC power at its rated value is defined. • A robust digital controller that damps current oscillations is designed. • The efficiency, power quality, lifetime, and robustness of the HPS are considered. • An experimental test on an original HPS emulator validates the proposed solutions. - Abstract: The aim of this research study has been to design a Hybrid Power System (HPS) which works with biogas and whose main components are a Solid Oxide Fuel Cell (SOFC), a Gas microTurbine (GT), and a module of SuperCapacities (SCs). The HPS is the only power source of a rural isolated microgrid. Its structure, operating strategy, and controller have been designed considering the following criteria: efficiency, power quality, SOFC lifetime and robustness in stability and performance. The HPS structure includes a unique power converter, a 3-Level Neutral Point Clamped (3LNPC) inverter that connects the HPS to the AC microgrid. Regarding the selected operating strategy, it consists in regulating the SOFC power output to its rated value. Thus, the SCs and the GT must respond to the power demand variations. On the other hand, a study of the HPS shows that its dynamic behavior is not linear. Therefore, a special attention is put on designing a robust HPS controller. The control model is identified and the robust digital controller is designed using the “Tracking and Regulation with Independent Objectives” method. Simulation and experimental results show how the proposed structure, operating strategy, and controller allow ensuring a good behavior of the HPS from the point of view of the abovementioned four criteria.

  9. Rotor scale model tests for power conversion unit of GT-MHR

    Energy Technology Data Exchange (ETDEWEB)

    Baxi, C.B.; Daugherty, R.; Shenoy, A. [General Atomics, 3550 General Atomics Court, CA (United States); Kodochigov, N.G.; Belov, S.E. [Experimental Design Bureau of Machine Building, N. Novgorad, RF (United States)

    2007-07-01

    The gas-turbine modular helium reactor (GT-MHR) combines a modular high-temperature gas-cooled reactor with a closed Brayton gas-turbine cycle power conversion unit (PCU) for thermal to electric energy conversion. The PCU has a vertical orientation and is supported on electromagnetic bearings (EMB). The Rotor Scale Model (RSM) Tests are intended to model directly the control of EMB and rotor-dynamic characteristics of the full-scale GT-MHR Turbo-machine. The objectives of the RSM tests are to: -1) confirm the EMB control system design for the GT-MHR turbo-machine over the full-range of operation, -2) confirm the redundancy and on-line maintainability features that have been specified for the EMBs, -3) provide a benchmark for validation of analytical tools that will be used for independent analyses of the EMB subsystem design, -4) provide experience with the installation, operation and maintenance of EMBs supporting multiple rotors with flexible couplings. As with the full-scale turbo-machine, the RSM will incorporate two rotors that are joined by a flexible coupling. Each of the rotors will be supported on one axial and two radial EMBs. Additional devices, similar in concept to radial EMBs, will be installed to simulate magnetic and/or mechanical forces representing those that would be seen by the exciter, generator, compressors and turbine. Overall, the length of the RSM rotor is about 1/3 that of the full-scale turbo-machine, while the diameter is approximately 1/5 scale. The design and sizing of the rotor is such that the number of critical speeds in the RSM are the same as in the full-scale turbo-machine. The EMBs will also be designed such that their response to rotor-dynamic forces is representative of the full-scale turbo-machine. (authors)

  10. Models development for the fuel design of a reactor GT-MHR

    International Nuclear Information System (INIS)

    Telesforo R, D.; Francois L, J. L.

    2009-10-01

    The very high temperature reactor (VHTR) it as arisen as an option for the following reactors generation, due to their characteristics as they are inherent security, modularity and relative low cost. One of the VHTR variants, for its fuel based on prismatic blocks, is the modular reactor cooled by gas GT-MHR that uses a fuel particle of multiple layers called TRISO. These particles are small containers with fuel in their interior and they function as small pressure vessels that retain the fission products. They are absorbed inconstant ing in a cylindrical graphite matrix to form the fuel named Compact; the quantity of fuel inventory is proportional to the packaging fraction on the total volume of the Compact. The reactor consists of a matrix of 12 X 12 graphite hexagonal assemblies contained in a cylinder of 3.5 radio meters and 10.0 meters high. The nucleus has ten axial regions with 36 X 3 fuel assemblies distributed in three rings. For the neutronic modeling of the fuel and the nucleus it was employee the Monte Carlo method, using the code MCNPX (Monte Carlo N-Particle version X) that is a transport code of general purposes that uses this method with a great versatility in the representation of arbitrary three-dimensional configurations and materials configuration. The heterogeneous model of the reactor GT-MHR core was obtained, adjusting the relative parameters at core prototype GT-MHR presented by General Atomics. To prove the model it was employee the fuel formed by TRISO particles, with a nucleus of 150 μm and packaging fraction of 37.55%, with a Uranium-235 mixture, as fissile nuclide, and Thorium-232. To create a simplified model of the nucleus, or homogeneous model, without modeling any particle, it was employee the reactivity-equivalent physical transformation method that captures the effects of the heterogeneity double of the fuel region in two homogeneous equivalent cells, being obtained very good results. (Author)

  11. Zeroth Poisson Homology, Foliated Cohomology and Perfect Poisson Manifolds

    Science.gov (United States)

    Martínez-Torres, David; Miranda, Eva

    2018-01-01

    We prove that, for compact regular Poisson manifolds, the zeroth homology group is isomorphic to the top foliated cohomology group, and we give some applications. In particular, we show that, for regular unimodular Poisson manifolds, top Poisson and foliated cohomology groups are isomorphic. Inspired by the symplectic setting, we define what a perfect Poisson manifold is. We use these Poisson homology computations to provide families of perfect Poisson manifolds.

  12. Perfect 2-colorings of the generalized Petersen graph

    Indian Academy of Sciences (India)

    There are no perfect 2-colorings of GP(n, 2) with the matrix A3. Proof. Suppose, contrary to our claim, there is a perfect 2-coloring of GP(n, 2) with the matrix A3. By Lemma 3.4, there are 2 vertices ai and bi, for some 0 ≤ i ≤ n−1, such that they are the same color. By symmetry, without loss of generality, we can assume T (a0) ...

  13. Research on vibration properties of auxiliary bearing cage used in HTR-10 GT project

    International Nuclear Information System (INIS)

    Qin Qingquan; Yang Guojun; Shi Zhengang; Yu Suyuan

    2009-01-01

    Auxiliary Bearings (ABs) is one of the most important parts in Active Magnetic Bearing (AMB) system, which was used in HTR-10 GT project. This paper uses finite element method to analyze the centrifugal stress and free vibration properties of the cage according to its work condition. And different geometric parameters of the cage that has effects on its vibration performance are discussed. The results show that the highest centrifugal stress is in the middle of the cage side sill. The low odder vibration modes of the cage can be induced when the auxiliary bearings are working. Proper geometric parameters and ball pocket number can enhance the performance of the cage. (authors)

  14. Colletotrichine B, a new sesquiterpenoid from Colletotrichum gloeosporioides GT-7, a fungal endophyte of Uncaria rhynchophylla.

    Science.gov (United States)

    Chen, Xiao-Wei; Yang, Zhong-Duo; Li, Xiao-Fei; Sun, Jian-Hui; Yang, Li-Jun; Zhang, Xin-Guo

    2018-02-08

    One new compound, colletotrichine B (1), was produced by the fungal Colletotrichum gloeosporioides GT-7. The structure of 1 was elucidated on the basis of spectroscopic analysis and X-ray crystallographic analysis. Monoamine oxidase (MAO), acetylcholinesterase (AChE) and phosphoinositide 3-kinase (PI3Kα) inhibitory activity of 1 was also evaluated. Compound 1 showed only AChE inhibiting activity with IC 50 value of 38.0 ± 2.67 μg/mL.

  15. Circuital model for the spherical geodesic waveguide perfect drain

    Science.gov (United States)

    González, Juan C.; Grabovičkić, Dejan; Benítez, Pablo; Miñano, Juan C.

    2012-08-01

    The perfect drain for the Maxwell fish eye (MFE) is a non-magnetic dissipative region placed in the focal point to absorb all the incident radiation without reflection or scattering. The perfect drain was recently designed as a material with complex permittivity that depends on frequency. However, this material is only a theoretical material, so it cannot be used in practical devices. The perfect drain has been claimed as necessary for achieving super-resolution (Leonhardt 2009 New J. Phys. 11 093040), which has increased the interest in practical perfect drains suitable for manufacturing. Here, we present a practical perfect drain that is designed using a simple circuit (made of a resistance and a capacitor) connected to the coaxial line. Moreover, we analyze the super-resolution properties of a device equivalent to the MFE, known as a spherical geodesic waveguide, loaded with this perfect drain. The super-resolution analysis for this device is carried out using COMSOL Multiphysics. The results of simulations predict a super-resolution of up to λ/3000.

  16. Circuital model for the spherical geodesic waveguide perfect drain

    International Nuclear Information System (INIS)

    González, Juan C; Grabovičkić, Dejan; Benítez, Pablo; Miñano, Juan C

    2012-01-01

    The perfect drain for the Maxwell fish eye (MFE) is a non-magnetic dissipative region placed in the focal point to absorb all the incident radiation without reflection or scattering. The perfect drain was recently designed as a material with complex permittivity that depends on frequency. However, this material is only a theoretical material, so it cannot be used in practical devices. The perfect drain has been claimed as necessary for achieving super-resolution (Leonhardt 2009 New J. Phys. 11 093040), which has increased the interest in practical perfect drains suitable for manufacturing. Here, we present a practical perfect drain that is designed using a simple circuit (made of a resistance and a capacitor) connected to the coaxial line. Moreover, we analyze the super-resolution properties of a device equivalent to the MFE, known as a spherical geodesic waveguide, loaded with this perfect drain. The super-resolution analysis for this device is carried out using COMSOL Multiphysics. The results of simulations predict a super-resolution of up to λ/3000. (paper)

  17. Development of new 6-speed manual transmission for SKYLINE GT-R; Skyline GT-R yo shingata 6 soku manual transmission no kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    Hayami, H.; Kawasaki, M.; Yamamoto, K.; Gaber, J. [Nissan Motor Co. Ltd., Tokyo (Japan)

    1999-06-01

    Described herein is a new 6-speed manual transmission (6MT), jointly developed for the new SKYLINE GT-R model. It adopts a close gear ratio, to realize light acceleration performance by improving drop of engine revolution number during the shift-up period by up to 12%. It has an increased synchro capacity by adopting a triple-cone synchro system for the first and second speeds, and double-cone synchro system for the third and fourth speeds, thereby decreasing shift operational force requirement by up to 35% from that for the conventional 5MT type. A non-symmetrical chamfer synchro structure is used for the second and third speeds, to reduce load generated when the speed is changed. The shift stroke is shortened by 24% by reviewing the dimensions. A high-rigidity shift lever and select stopper structure are adopted, to improve shift rigidity sensation. The transmission case is optimized, to reduce its weight while securing its rigidity. Transmission oil temperature is decreased by installing a cooling fan and increasing overdrive gear ratio. (NEDO)

  18. Feasibility study for SOFC-GT hybrid locomotive power: Part I. Development of a dynamic 3.5 MW SOFC-GT FORTRAN model

    Science.gov (United States)

    Martinez, Andrew S.; Brouwer, Jacob; Samuelsen, G. Scott

    2012-09-01

    This work presents the development of a dynamic SOFC-GT hybrid system model applied to a long-haul freight locomotive in operation. Given the expectations of the rail industry, the model is used to develop a preliminary analysis of the proposed system's operational capability on conventional diesel fuel as well as natural gas and hydrogen as potential fuels in the future. It is found that operation of the system on all three of these fuels is feasible with favorable efficiencies and reasonable dynamic response. The use of diesel fuel reformate in the SOFC presents a challenge to the electrochemistry, especially as it relates to control and optimization of the fuel utilization in the anode compartment. This is found to arise from the large amount of carbon monoxide in diesel reformate that is fed to the fuel cell, limiting the maximum fuel utilization possible. This presents an opportunity for further investigations into carbon monoxide electrochemical oxidation and/or system integration studies where the efficiency of the fuel reformer can be balanced against the needs of the SOFC.

  19. Brain pericyte-derived soluble factors enhance insulin sensitivity in GT1-7 hypothalamic neurons.

    Science.gov (United States)

    Takahashi, Hiroyuki; Takata, Fuyuko; Matsumoto, Junichi; Machida, Takashi; Yamauchi, Atsushi; Dohgu, Shinya; Kataoka, Yasufumi

    2015-02-20

    Insulin signaling in the hypothalamus plays an important role in food intake and glucose homeostasis. Hypothalamic neuronal functions are modulated by glial cells; these form an extensive network connecting the neurons and cerebral vasculature, known as the neurovascular unit (NVU). Brain pericytes are periendothelial accessory structures of the blood-brain barrier and integral members of the NVU. However, the interaction between pericytes and neurons is largely unexplored. Here, we investigate whether brain pericytes could affect hypothalamic neuronal insulin signaling. Our immunohistochemical observations demonstrated the existence of pericytes in the mouse hypothalamus, exhibiting immunoreactivity of platelet-derived growth factor receptor β (a pericyte marker), and laminin, a basal lamina marker. We then exposed a murine hypothalamic neuronal cell line, GT1-7, to conditioned medium obtained from primary cultures of rat brain pericytes. Pericyte-conditioned medium (PCM), but not astrocyte- or aortic smooth muscle cell-conditioned medium, increased the insulin-stimulated phosphorylation of Akt in GT1-7 cells in a concentration-dependent manner. PCM also enhanced insulin-stimulated tyrosine phosphorylation of insulin receptor β without changing its expression or localization in cytosolic or plasma membrane fractions. These results suggest that pericytes, rather than astrocytes, increase insulin sensitivity in hypothalamic neurons by releasing soluble factors under physiological conditions in the NVU. Copyright © 2015 Elsevier Inc. All rights reserved.

  20. GT-SUPREEM: the Georgia Tech summer undergraduate packaging research and engineering experience for minorities

    Science.gov (United States)

    May, Gary S.

    1996-07-01

    The Georgia Tech SUmmer Undergraduate Packaging Research and Engineering Experience for Minorities (GT-SUPREEM) is an eight-week summer program designed to attract qualified minority students to pursue graduate degrees in packaging- related disciplines. The program is conducted under the auspices of the Georgia Tech Engineering Research Center in Low-Cost Electronic Packaging, which is sponsored by the National Science Foundation. In this program, nine junior and senior level undergraduate students are selected on a nationwide basis and paired with a faculty advisor to undertake research projects in the Packaging Research CEnter. The students are housed on campus and provided with a $DLR3,000 stipend and a travel allowance. At the conclusion of the program, the students present both oral and written project summaries. It is anticipated that this experience will motivate these students to become applicants for graduate study in ensuring years. This paper will provide an overview of the GT-SUPREEM program, including student research activities, success stories, lessons learned, and overall program outlook.

  1. Endometrial cancer and somatic G>T KRAS transversion in patients with constitutional MUTYH biallelic mutations.

    Science.gov (United States)

    Tricarico, Rossella; Bet, Paola; Ciambotti, Benedetta; Di Gregorio, Carmela; Gatteschi, Beatrice; Gismondi, Viviana; Toschi, Benedetta; Tonelli, Francesco; Varesco, Liliana; Genuardi, Maurizio

    2009-02-18

    MUTYH-associated polyposis (MAP) is an autosomal recessive condition predisposing to colorectal cancer, caused by constitutional biallelic mutations in the base excision repair (BER) gene MUTYH. Colorectal tumours from MAP patients display an excess of somatic G>T mutations in the APC and KRAS genes due to defective BER function. To date, few extracolonic manifestations have been observed in MAP patients, and the clinical spectrum of this condition is not yet fully established. Recently, one patient with a diagnosis of endometrial cancer and biallelic MUTYH mutations has been described. We here report on two additional unrelated MAP patients with biallelic MUTYH germline mutations who developed endometrioid endometrial carcinoma. The endometrial tumours were evaluated for PTEN, PIK3CA, KRAS, BRAF and CTNNB1 mutations. A G>T transversion at codon 12 of the KRAS gene was observed in one tumour. A single 1bp frameshift deletion of PTEN was observed in the same sample. Overall, these findings suggest that endometrial carcinoma is a phenotypic manifestations of MAP and that inefficient repair of oxidative damage can be involved in its pathogenesis.

  2. Nuclear closed-cycle gas turbine (HTGR-GT): dry cooled commercial power plant studies

    International Nuclear Information System (INIS)

    McDonald, C.F.; Boland, C.R.

    1979-11-01

    Combining the modern and proven power conversion system of the closed-cycle gas turbine (CCGT) with an advanced high-temperature gas-cooled reactor (HTGR) results in a power plant well suited to projected utility needs into the 21st century. The gas turbine HTGR (HTGR-GT) power plant benefits are consistent with national energy goals, and the high power conversion efficiency potential satisfies increasingly important resource conservation demands. Established technology bases for the HTGR-GT are outlined, together with the extensive design and development program necessary to commercialize the nuclear CCGT plant for utility service in the 1990s. This paper outlines the most recent design studies by General Atomic for a dry-cooled commercial plant of 800 to 1200 MW(e) power, based on both non-intercooled and intercooled cycles, and discusses various primary system aspects. Details are given of the reactor turbine system (RTS) and on integrating the major power conversion components in the prestressed concrete reactor vessel

  3. A study on the design concepts of the PBMR and the GT-MHR

    International Nuclear Information System (INIS)

    Park, Won Seok; Chang, Jong Hwa; Park, Chang Kue

    2004-05-01

    The major application of the nuclear power in the energy sector has been to produce the electricity. However, a growing concern on the environment and the expected shortage of the fossil energy resources is demanding the expansion of nuclear energy's role in the energy sectors. The High Temperature Gas cooled Reactor (HTGR) has been expected to expand the role of nuclear energy because of its high temperature capability. Especially, the interest on the HTGR has been sharply increased recently related with the production of the hydrogen. About 5 HTGRs had been operated by the end of 1980s. However, all of them had been terminated permanently at the end of 1980s because of their poor system economy and frequent technical troubles. A new concept called MHTGR (Modular High Temperature Gas cooled Reactor) emerged in early of 1990s. Two MHTGR concepts on commercial basis have been developed since then; one is the PBMR (Pebble Bed Modular Reactor) developed by Eskom in South Africa and another is GT-MHR (Gas Turbine Modular High-temperature Reactor) developed by both GA in USA and OKBM in Russia. In this report, the design concepts for the PBMR and GT-MHR were reviewed

  4. Thermoeconomic analysis of Biomass Integrated Gasification Gas Turbine Combined Cycle (BIG GT CC) cogeneration plant

    Energy Technology Data Exchange (ETDEWEB)

    Arrieta, Felipe Raul Ponce; Lora, Electo Silva [Escola Federal de Engenharia de Itajuba, MG (Brazil). Nucleo de Estudos de Sistemas Termicos]. E-mails: aponce@iem.efei.br; electo@iem.efei.br; Perez, Silvia Azucena Nebra de [Universidade Estadual de Campinas, SP (Brazil). Faculdade de Engenharia Mecanica. Dept. de Energia]. E-mail: sanebra@fem. unicamp.br

    2000-07-01

    Using thermoeconomics as a tool to identify the location and magnitude of the real thermodynamic losses (energy waste, or exergy destruction and exergy losses) it is possible to assess the production costs of each product (electric power and heat) and the exergetic and exergoeconomic cost of each flow in a cogeneration plant to assist in decision-marketing procedures concerning to plant design, investment, operation and allocations of research funds. Thermo economic analysis of Biomass Integrated Gasification Gas Turbine Combined Cycle (BIG GT CC) cogeneration plant for its applications in sugar cane mills brings the following results: the global exergetic efficiency is low; the highest irreversibilities occur in the following equipment, by order: scrubber (38%), gas turbine (16%), dryer (12%), gasifier and HRSG (6%); due to the adopted cost distribution methodology, the unit exergetic cost of the heat (4,11) is lower than electricity (4,71); the lower market price of biomass is one of the most sensible parameter in the possible implementation of BIG-GT technology in sugar cane industry; the production costs are 31 US$/MWh and 32 US$/MWh for electricity and heat, respectively. The electricity cost is, after all, competitive with the actual market price. The electricity and heat costs are lower or almost equal than other values reported for actual Rankine cycle cogeneration plants. (author)

  5. The GT-MHR - clear, economic, and safe power for the Pacific Rim

    International Nuclear Information System (INIS)

    Blue, L.S.; Etzel, K.T.; Simon, W.A.; Wistrom, J.D.

    1994-01-01

    In recent decades the nations of the Pacific Rim have outpaced the rest of the world in economic growth. Beyond an abundant labor market and the region's natural resources, energy has played a pivotal role in fuelling this boom. The diverse sources of this energy largely reflect the naturally occurring fuel assets in the Rim countries. Only in the countries where these resources are less plentiful has nuclear energy become a significant sources of electric power generation. Persuasive as the argument for non-polluting power may be by itself it does not sell the nuclear energy option. In addition to being clean it must also be economically competitive and very safe. The authors claim that the Gas-Turbine Modular Helium Reactor (GT-MHR) is an advances nuclear power system that addresses the issues, and should be viewed as an attractive candidate to meet future energy needs. The GT-MHR derives from the coupling of a small, passively safe, modular reactor directly with a compact power conversion module. It uses the Brayton cycle to produce electricity directly with the primary helium coolant driving the turbine-generator. Thus, it shows promise for a quantum reduction in power generation costs by increasing plant efficiency to a remarkable 48% This paper highlights the advantages of the fact that the design is based on proven technology, and offers a clean, economic and safe energy for electricity and high temperature process heat. 2 refs., 4 figs

  6. A study on the design concepts of the PBMR and the GT-MHR

    Energy Technology Data Exchange (ETDEWEB)

    Park, Won Seok; Chang, Jong Hwa; Park, Chang Kue

    2004-05-01

    The major application of the nuclear power in the energy sector has been to produce the electricity. However, a growing concern on the environment and the expected shortage of the fossil energy resources is demanding the expansion of nuclear energy's role in the energy sectors. The High Temperature Gas cooled Reactor (HTGR) has been expected to expand the role of nuclear energy because of its high temperature capability. Especially, the interest on the HTGR has been sharply increased recently related with the production of the hydrogen. About 5 HTGRs had been operated by the end of 1980s. However, all of them had been terminated permanently at the end of 1980s because of their poor system economy and frequent technical troubles. A new concept called MHTGR (Modular High Temperature Gas cooled Reactor) emerged in early of 1990s. Two MHTGR concepts on commercial basis have been developed since then; one is the PBMR (Pebble Bed Modular Reactor) developed by Eskom in South Africa and another is GT-MHR (Gas Turbine Modular High-temperature Reactor) developed by both GA in USA and OKBM in Russia. In this report, the design concepts for the PBMR and GT-MHR were reviewed.

  7. The Pentapeptide Repeat Proteins

    OpenAIRE

    Vetting, Matthew W.; Hegde, Subray S.; Fajardo, J. Eduardo; Fiser, Andras; Roderick, Steven L.; Takiff, Howard E.; Blanchard, John S.

    2006-01-01

    The Pentapeptide Repeat Protein (PRP) family has over 500 members in the prokaryotic and eukaryotic kingdoms. These proteins are composed of, or contain domains composed of, tandemly repeated amino acid sequences with a consensus sequence of [S,T,A,V][D,N][L,F]-[S,T,R][G]. The biochemical function of the vast majority of PRP family members is unknown. The three-dimensional structure of the first member of the PRP family was determined for the fluoroquinolone resistance protein (MfpA) from Myc...

  8. Repeated Causal Decision Making

    Science.gov (United States)

    Hagmayer, York; Meder, Bjorn

    2013-01-01

    Many of our decisions refer to actions that have a causal impact on the external environment. Such actions may not only allow for the mere learning of expected values or utilities but also for acquiring knowledge about the causal structure of our world. We used a repeated decision-making paradigm to examine what kind of knowledge people acquire in…

  9. simple sequence repeat (SSR)

    African Journals Online (AJOL)

    In the present study, 78 mapped simple sequence repeat (SSR) markers representing 11 linkage groups of adzuki bean were evaluated for transferability to mungbean and related Vigna spp. 41 markers amplified characteristic bands in at least one Vigna species. The transferability percentage across the genotypes ranged ...

  10. Forbidden Structures for Planar Perfect Consecutively Colourable Graphs

    Directory of Open Access Journals (Sweden)

    Borowiecka-Olszewska Marta

    2017-05-01

    Full Text Available A consecutive colouring of a graph is a proper edge colouring with posi- tive integers in which the colours of edges incident with each vertex form an interval of integers. The idea of this colouring was introduced in 1987 by Asratian and Kamalian under the name of interval colouring. Sevast- janov showed that the corresponding decision problem is NP-complete even restricted to the class of bipartite graphs. We focus our attention on the class of consecutively colourable graphs whose all induced subgraphs are consecutively colourable, too. We call elements of this class perfect consecutively colourable to emphasise the conceptual similarity to perfect graphs. Obviously, the class of perfect consecutively colourable graphs is induced hereditary, so it can be characterized by the family of induced forbidden graphs. In this work we give a necessary and sufficient conditions that must be satisfied by the generalized Sevastjanov rosette to be an induced forbid- den graph for the class of perfect consecutively colourable graphs. Along the way, we show the exact values of the deficiency of all generalized Sevastjanov rosettes, which improves the earlier known estimating result. It should be mentioned that the deficiency of a graph measures its closeness to the class of consecutively colourable graphs. We motivate the investigation of graphs considered here by showing their connection to the class of planar perfect consecutively colourable graphs.

  11. Repeated radiation injuries by fission products

    International Nuclear Information System (INIS)

    Vasilenko, I.Ya.

    1986-01-01

    Attention is given to repeated radiation injuries during internal irradiation of theoretical and practical interest, particularly in case of the intake into organism of young products of nuclear fission (PNF). The results of experiments with dogs with repeated radioactive iodine injury the isotopes of which (131-135sub(I)) constitute a considerable part of PNF activity are discussed. The blood reaction and protein metabolism state have been studied. Observations for dogs have been continued for about 4 years. The doses for thyroid, gastrointestinal tract and liver subjected to the most intensive irradiation consituted in the first series of experiments after the first intake about 3;0.3;0.05 Gy, after the second - 5;0.5;0.08 Gy and in the second series of experiments - 3;0.3;0.05 Gy and 0.6;0.06;0.01 Gy, respectively. Hematologic factors,thyroid function, changes in exchange and immunologic reactivity have been studied. The dogs have been under observation for 5 years. It is shown in case of repeated intake of Isup(131) PNF into animals organism in quantity which does not cause during the acute period a clinically outlined sickness, substantial differences in the organism reaction as compared with the first intake of radionuclides have not been found. The presence of residual radiation injuries did not cause charging action during the acute period during PNF and repeated intake which in the author's opinion testifies to perfection of compensator mechanisms in case of intake of such quantities of radioactive products. At the remote periods blastomogenic action manifested which is estimated as a result of general biological action of radionuclides administered to the organism. The necessity in subsequent investigations for obtaining the data on organism reactivity, clinic and pathogenesis with the aim of prophylaxis and treatment of such injuries is indicated

  12. Overview of Hole GT3A: The sheeted dike/gabbro transition

    Science.gov (United States)

    Abe, N.; Harris, M.; Michibayashi, K.; de Obeso, J. C.; Kelemen, P. B.; Takazawa, E.; Teagle, D. A. H.; Coggon, J. A.; Matter, J. M.; Phase I Science Party, T. O. D. P.

    2017-12-01

    Hole GT3A (23.11409 N, 58.21172 E) was drilled by the Oman Drilling Project (OmDP) into Wadi Abdah of the Samail ophiolite, Oman. OmDP is an international collaboration supported by the International Continental Scientifi1c Drilling Program, the Deep Carbon Observatory, NSF, IODP, JAMSTEC, and the European, Japanese, German and Swiss Science Foundations, with in-kind support in Oman from the Ministry of Regional Municipalities and Water Resources, Public Authority of Mining, Sultan Qaboos University, and the German University of Technology. Hole GT3A was diamond cored in February to March 2017 to a total depth of 400 m. The outer surfaces of the cores were imaged and described on site before being curated, boxed and shipped to the IODP drill ship Chikyu, where they underwent comprehensive visual and instrumental analysis. Hole GT3A recovered predominantly sheeted dikes and gabbros and has been sub-divided into 4 igneous groups based on the abundance of gabbro downhole. Group 1 (Upper Sheeted Dike Sequence) occurs from 0 to 111.02 m, group II (Upper Gabbro Sequence) is from 111.02 to 127.89 m, group III (Lower Sheeted Dike Sequence) is between 127.89 to 233.84 m and group IV (Lower Gabbro Sequence) is from 233.84 to 400 m. Group II and IV are both associated with almost equal proportions of dikes to gabbroic lithologies, whereas group I & III have >95% dikes. The sheeted dikes were logged as either basalt (46.9 %) or diabase (26.2 %) depending on the predominant grain size of the dike. Gabbroic lithologies include (most to least abundant) gabbro, oxide gabbro and olivine gabbro. Other lithologies present include diorite (7.5%) and tonalite and trondhjemite (1%). Tonalite and trondhjemite are present as cm-sized dikelets and are found within group II and IV. Gabbroic lithologies generally display a varitextured appearance and are characterised by the co-existence of poikilitic and granular domains. Detailed observations of chilled margins and igneous contacts reveal

  13. Rotor scale model tests for power conversion unit of GT-MHR

    Energy Technology Data Exchange (ETDEWEB)

    Baxi, C.B., E-mail: baxicb1130@hotmail.com [General Atomics, P.O. Box 85608, San Diego, CA 92186-5608 (United States); Telengator, A.; Razvi, J. [General Atomics, P.O. Box 85608, San Diego, CA 92186-5608 (United States)

    2012-10-15

    The gas turbine modular helium reactor (GT-MHR) combines a modular high-temperature gas-cooled reactor (HTGR) nuclear heat source with a closed Brayton gas-turbine cycle power conversion unit (PCU) for thermal to electric energy conversion. The PCU has a vertical orientation and is supported on electromagnetic bearings (EMB). The rotor scale model (RSM) tests are intended to directly model the control of EMB and rotor dynamic characteristics of the full-scale GT-MHR turbo-machine (TM). The objectives of the RSM tests are to: Bullet Confirm the EMB control system design for the GT-MHR turbo machine over the full-range of operation. Bullet Confirm the redundancy and on-line maintainability features that have been specified for the EMBs. Bullet Provide a benchmark for validation of analytical tools that will be used for independent analyses of the EMB subsystem design. Bullet Provide experience with the installation, operation and maintenance of EMBs supporting multiple rotors with flexible couplings. As with the full-scale TM, the RSM incorporates two rotors that are joined by a flexible coupling. Each of the rotors is supported on one axial and two radial EMBs. Additional devices, similar in concept to radial EMBs, are installed to simulate magnetic and/or mechanical forces representing those that would be seen by the exciter, generator, compressors and turbine. Overall, the lengths of the RSM rotor is about 1/3rd that of the full-scale TM, while the diameters are approximately 1/5th scale. The design and sizing of the rotor is such that the number and values of critical speeds in the RSM are the same as in the full-scale TM. The EMBs are designed such that their response to rotor dynamic forces is representative of the full-scale TM. The fabrication and assembly of the RSM was completed at the end of 2008. All start up adjustments were finished in December 2009. To-date the generator rotor has been supported in the EMBs and rotated up to 1800 rpm. Final tests are

  14. Oman Drilling Project GT3 site survey: dynamics at the roof of an oceanic magma chamber

    Science.gov (United States)

    France, L.; Nicollet, C.; Debret, B.; Lombard, M.; Berthod, C.; Ildefonse, B.; Koepke, J.

    2017-12-01

    Oman Drilling Project (OmanDP) aims at bringing new constraints on oceanic crust accretion and evolution by drilling Holes in the whole ophiolite section (mantle and crust). Among those, operations at GT3 in the Sumail massif drilled 400 m to sample the dike - gabbro transition that corresponds to the top (gabbros) and roof (dikes) of the axial magma chamber, an interface where hydrothermal and magmatic system interacts. Previous studies based on oceanic crust formed at present day fast-spreading ridges and preserved in ophiolites have highlighted that this interface is a dynamic horizon where the axial melt lens that top the main magma chamber can intrude, reheat, and partially assimilate previously hydrothermally altered roof rocks. Here we present the preliminary results obtained in GT3 area that have allowed the community to choose the drilling site. We provide a geological and structural map of the area, together with new petrographic and chemical constraints on the dynamics of the dike - gabbro transition. Our new results allow us to quantify the dynamic processes, and to propose that 1/ the intrusive contact of the varitextured gabbro within the dikes highlights the intrusion of the melt lens top in the dike rooting zone, 2/ both dikes and previously crystallized gabbros are reheated, and recrystallized by underlying melt lens dynamics (up to 1050°C, largely above the hydrous solidus temperature of altered dikes and gabbros), 3/ the reheating range can be > 200°C, 4/ the melt lens depth variations for a given ridge position is > 200m, 5/ the reheating stage and associated recrystallization within the dikes occurred under hydrous conditions, 6/ the reheating stage is recorded at the root zone of the sheeted dike complex by one of the highest stable conductive thermal gradient ever recorded on Earth ( 3°C/m), 7/ local chemical variations in recrystallized dikes and gabbros are highlighted and used to quantify crystallization and anatectic processes, and the

  15. Perfect transfer of arbitrary states in quantum spin networks

    International Nuclear Information System (INIS)

    Christandl, Matthias; Kay, Alastair; Datta, Nilanjana; Dorlas, Tony C.; Ekert, Artur; Landahl, Andrew J.

    2005-01-01

    We propose a class of qubit networks that admit perfect state transfer of any two-dimensional quantum state in a fixed period of time. We further show that such networks can distribute arbitrary entangled states between two distant parties, and can, by using such systems in parallel, transmit the higher-dimensional systems states across the network. Unlike many other schemes for quantum computation and communication, these networks do not require qubit couplings to be switched on and off. When restricted to N-qubit spin networks of identical qubit couplings, we show that 2 log 3 N is the maximal perfect communication distance for hypercube geometries. Moreover, if one allows fixed but different couplings between the qubits then perfect state transfer can be achieved over arbitrarily long distances in a linear chain. This paper expands and extends the work done by Christandl et al., Phys. Rev. Lett. 92, 187902 (2004)

  16. [INVITED] Coherent perfect absorption of electromagnetic wave in subwavelength structures

    Science.gov (United States)

    Yan, Chao; Pu, Mingbo; Luo, Jun; Huang, Yijia; Li, Xiong; Ma, Xiaoliang; Luo, Xiangang

    2018-05-01

    Electromagnetic (EM) absorption is a common process by which the EM energy is transformed into other kinds of energy in the absorber, for example heat. Perfect absorption of EM with structures at subwavelength scale is important for many practical applications, such as stealth technology, thermal control and sensing. Coherent perfect absorption arises from the interplay of interference and absorption, which can be interpreted as a time-reversed process of lasing or EM emitting. It provides a promising way for complete absorption in both nanophotonics and electromagnetics. In this review, we discuss basic principles and properties of a coherent perfect absorber (CPA). Various subwavelength structures including thin films, metamaterials and waveguide-based structures to realize CPAs are compared. We also discuss the potential applications of CPAs.

  17. Whole genome association mapping by incompatibilities and local perfect phylogenies

    DEFF Research Database (Denmark)

    Mailund, Thomas; Besenbacher, Søren; Schierup, Mikkel Heide

    2006-01-01

    around each marker that is compatible with a single phylogenetic tree. This perfect phylogenetic tree is treated as a decision tree for determining disease status, and scored by its accuracy as a decision tree. The rationale for this is that the perfect phylogeny near a disease affecting mutation should...... a fast method for accurate localisation of disease causing variants in high density case-control association mapping experiments with large numbers of cases and controls. The method searches for significant clustering of case chromosomes in the "perfect" phylogenetic tree defined by the largest region...... provide more information about the affected/unaffected classification than random trees. If regions of compatibility contain few markers, due to e.g. large marker spacing, the algorithm can allow the inclusion of incompatibility markers in order to enlarge the regions prior to estimating their phylogeny...

  18. Dual band metamaterial perfect absorber based on Mie resonances

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Xiaoming; Lan, Chuwen; Li, Bo; Zhou, Ji, E-mail: zhouji@tsinghua.edu.cn [State Key Laboratory of New Ceramics and Fine Processing, School of Materials Science and Engineering, Tsinghua University, Beijing 100084 (China); Bi, Ke [School of Science, Beijing University of Posts and Telecommunications, Beijing 100876 (China); Zhao, Qian [State Key Lab of Tribology, Department of Precision Instruments and Mechanology, Tsinghua University, Beijing 100084 (China)

    2016-08-08

    We numerically and experimentally demonstrated a polarization insensitive dual-band metamaterial perfect absorber working in wide incident angles based on the two magnetic Mie resonances of a single dielectric “atom” with simple structure. Two absorption bands with simulated absorptivity of 99% and 96%, experimental absorptivity of 97% and 94% at 8.45 and 11.97 GHz were achieved due to the simultaneous magnetic and electric resonances in dielectric “atom” and copper plate. Mie resonances of dielectric “atom” provide a simple way to design metamaterial perfect absorbers with high symmetry.

  19. Perfect lensing with phase-conjugating surfaces: toward practical realization

    International Nuclear Information System (INIS)

    Maslovski, Stanislav; Tretyakov, Sergei

    2012-01-01

    It is theoretically known that a pair of phase-conjugating surfaces can function as a perfect lens, focusing propagating waves and enhancing evanescent waves. However, the known experimental approaches based on thin sheets of nonlinear materials cannot fully realize the required phase conjugation boundary condition. In this paper, we show that the ideal phase-conjugating surface is, in principle, physically realizable and investigate the necessary properties of nonlinear and nonreciprocal particles which can be used to build a perfect lens system. The physical principle of the lens operation is discussed in detail and directions of possible experimental realizations are outlined. (paper)

  20. Hydrogen can be used as a perfect fuel

    International Nuclear Information System (INIS)

    Aydin, E.

    2005-01-01

    At present, hydrogen is one of the new and clean energy production sources. Hydrogen is the perfect partner for electricity, and together they create an integrated energy system based on distributed power generation and use. Hydrogen and electricity are interchangeable using a fuel cell (to convert hydrogen to electricity) or an electrolyzer (for converting electricity to hydrogen). A regenerative fuel cell works either way, converting hydrogen to electricity and vice versa. Hydrogen and electricity are both energy carriers because, unlike naturally occurring hydrocarbon fuels, they must both be produced using a primary energy source. In this study, it will be discussed whether hydrogen is perfect fuel or not

  1. Bio sorption of strontium from aqueous solution by the new strain of bacillus sp. strain GT-83

    International Nuclear Information System (INIS)

    Tajer Mohammad Ghazvini, P.; Ghorbanzadeh Mashkani, S.; Mazaheri, M.

    2009-01-01

    An attempt was made to isolate bacterial strains capable of removing strontium biologically. In this study ten different water samples collected from Neydasht spring in the north of Iran and then the bacterial species were isolated from the water samples. The initial screening of a total of 50 bacterial isolates resulted in selection of one strain.The isolated strain showed a maximum adsorption capacity with 55 milligrams strontium/g dry wt. It was tentatively identified as Bacillus sp. According to the morphological and biochemical properties, and called strain GT-83. Our studies indicated that Bacillus sp. GT-83 is able to grow aerobically in the presence of 50 mM SrCl 2 , but its growth was inhibited at high levels of strontium concentrations. The bio sorption capacity of Bacillus sp. GT-83 depends strongly on the p H solution. Hence the maximum strontium sorption capacity of Bacillus sp. GT-83 was obtained at pah 10, independent of absence or presence of MgCl 2 of different concentrations. Strontium-salt bio sorption studies were also performed at this p H values. The equilibrium bio sorption of strontium was elevated by increasing the strontium concentration, up to 250 milligrams/l for Bacillus sp. GT-83. The maximum bio sorption of strontium was obtained at temperatures in the range of 30-35 d eg C . The Bacillus sp. GT-83 bio sorbed 97 milligrams strontium/g dry wt at 100 milligrams/l initial strontium concentration without MgCl 2 . When MgCl 2 concentration increased to 15%(w/v), these values dropped to 23.6 milligrams strontium/g dry wt at the same conditions. Uptake of strontium within 5 min of incubation was relatively rapid and the absorption continued slowly thereafter

  2. WBP/SIGAME the Brazilian BIG-GT demonstration project actual status and perspectives

    International Nuclear Information System (INIS)

    Carpentier, E.; Silva, A.

    1998-01-01

    Located in the tropics, with the sun shining all year round, and with its vast territory, Brazil may be regarded as having all the basic conditions to develop a modern Biomass for Electricity industry. Those characteristics together with: (a) the necessity of developing new energy resources for electricity production, in the northeast of the country; (b) the results of studies made by various entities, including CHESF; (c) the progress achieved by the BIG-GT technology; (d) the organisation of the Global Environment Facility (GEF); (e) and the support of the Brazilian government, through the Ministry of Science and Technology (MCT), provided the unique opportunity for the implementation of a commercial demonstration of that technology in Brazil. This paper describes the idea, scope, challenges, lessons, and actual status of development of the WBP/SIGAME project. It also highlights some institutional issues, budget figures, and energy prices. (author)

  3. Neutronic evaluation of a fuel block of a GT-MHR using WIMSD5

    International Nuclear Information System (INIS)

    Silva, Clarysson Alberto Mello da; Pereira, Claubia; Costa, Antonella Lombardi; Veloso, Maria Auxiliadora Fortini

    2009-01-01

    The goal is to simulate a representative fuel block of a GT-MHR core to analyze the neutronic parameters behavior due the insertion of Pu isotopes and Minor Actinides (MAs) using shuffling scheme. Initially the fuel block was filled with Driver Fuel (DF), and after burned, these fuels are reprocessed and build the Transmutation Fuel (TF). After some cycles, the fuel block was filled with DF and TF fuels. The DF is a mixture of Pu and Np and the TF is a mix of Pu and MAs. The shuffled scheme was evaluated after each cycle. It was verified that neutronic parameters and isotopic composition reach equilibrium and remain within safety limits when this scheme is used. In addition, there were burnup of MAs. The WIMS code was used in the simulations and the following neutronic parameters were evaluated: infinitive multiplication factor, spectrum hardening and reactivity temperature coefficients. (author)

  4. Status of GT-MHR with emphasis on the power conversion system

    International Nuclear Information System (INIS)

    Neylan, A.J.; Silady, F.A.; Kohler, B.P.; Lomba, D.; Rose, R.

    1996-01-01

    The conceptual design of the Gas Turbine-Modular Helium Reactor (GT-MHR) has made significant progress in the past year. Evaluation of an external versus internal (submerged) generator and modifications as a result of an internal seal task force were completed. Significant progress was also made on the design of the generator utilizing existing technology. Conceptual design of the turbocompressor was confirmed, including extensive evaluation of the entire turbomachine (turbocompressor and generator) rotor dynamics. Results concluded in a revised configuration for the location of magnetic bearings supporting the entire machine. Integration of the turbomachine with the recuperator, precooler, intercooler and internal ducts and seals progressed to improved maintenance and operation. This resulted in some changes and improvements in the overall arrangement of the power conversion module. The paper also provides a summary of the fuel and safety assessment progress. (author). 6 refs, 7 figs, 3 tabs

  5. Actual characteristics study on HTR-10GT coupling with direct gas turbine cycle

    International Nuclear Information System (INIS)

    Peng Xuechuang; Zhu Shutang; Wang Jie

    2005-01-01

    Compared with a plant of steam turbine cycle, a HTGR plant with direct gas turbine cycle has a higher thermal efficiency. A lot of investigations on the characteristics of HTR-10GT, which is the reactor studying project of Tsinghua University, have been carried out, however, all of them are based on the theoretical Brayton Cycle which neglects many actual conditions, such as leakage, pressure loss and so on. For engineering practices, leakage is an unavoidable problem. The difference of the location and capacity of leakage will directly influence the working medium's thermoparameters and lead to fall of the cycle efficiency. The present study is focused on the performance of an actual Brayton cycle with practical conditions of leakage. The present study which based on building the physical and mathematical model of the leakage, aims to study the actual characteristics of the direct gas turbine circle. (authors)

  6. Management system and potential markets for a HTR-GT plant

    International Nuclear Information System (INIS)

    Crommelin, G.A.K.

    1997-01-01

    This article will discuss some aspects which could be helpful to execute a HTR-GT study successfully: 1. The preferred type of organisation for such a study; in order to achieve a maximum of support in society and industry, a minimum of through life costing and a maximum of through life support. 2. The lead time needed for such studies i.e. the design, component testing, prototype testing, the required efficiency, the type of energy in quantity and quality, financial targets, controllability, maintainability and reliability. 3. The potential markets for the nuclear gasturbine driven energy plants in the low power range. Analyses of the markets will be explained from the user's point of view on why, when and how, for what purpose, in which power range, as well as how many units per application would be required. (author)

  7. Slurry Ice as a Cooling System on 30 GT Fishing Vessel

    Directory of Open Access Journals (Sweden)

    Alam Baheramsyah

    2017-06-01

    Full Text Available Indonesia is the largest archipelago country in the world that has a sea area that is very spacious. Indonesian sea area is 5.8 million square kilometers and a coastline of 95 181 km has huge potential in the fisheries sector. In line with the need to further improve on the quality of the fish catch. One way to preserve fish is to use a slurry of ice. Slurry ice proved more effective preserving fishery products instead of using ice cubes. Ice slurry cooling system was designed and applied to the fishing vessel 30 GT. The cooling system uses a simple vapor compression system consists of five major components consisting of evaporator, condenser, compressor, and two pumps.In designing this system determined the type of refrigerant used in advance which type of refrigerant R-507a. Then do the design or selection of its main components. The design is only done on the evaporator. As for the other major components such as condensers, compressors, and pumps election in accordance with the specification of the power needed. After that dialakukan depiction of each system component. Then subsequently designing the laying of ice slurry cooling system components on a fishing vessel 30 GT.            Through calculations using simple thermodynamic equations obtained cooling load on this system amounted to 32.06 kW. Condenser with a power of 40 kW. Compressor with power 12 kW. Pump with capacity 10 m3 / h. With memepertimbangkan space left on the ship in the ice slurry system design on the main deck of the ship to the efficient use of space on board. The power requirements of the generator vessel increases due to the addition of ice slurry system components therefore do replacement generator into the generator with a power of 100 kW and penambahn fuel tank to 6,000 L.

  8. Clinical utilisation of the "G.T. MSRS", the rating scale for mixed states: 35 cases report.

    Science.gov (United States)

    Tavormina, Giuseppe

    2015-09-01

    The knowledge of the clinical features of the mixed states and of the symptoms of the "mixity" of mood disorders is crucial: to mis-diagnose or mis-treat patients with these symptoms may increase the suicide risk and make worse the evolution of mood disorders. The rating scale "G.T. MSRS" has been designed to improve the clinical effectiveness of both psychiatrists and GPs by enabling them to make an early "general" diagnosis of mixed states. This study presents some cases in which the "G.T. MSRS" scale has been used, in order to demonstrate its usefullness.

  9. Clinical Utilisation and Usefullness of the Rating Scale of Mixed States, ("Gt-Msrs"): a Multicenter Study.

    Science.gov (United States)

    Tavormina, Giuseppe; Franza, Francesco; Stranieri, Giuseppe; Juli, Luigi; Juli, Maria Rosaria

    2017-09-01

    The rating scale "G.T. MSRS" has been designed to improve the clinical effectiveness of the clinician psychiatrists, by enabling them to make an early "general" diagnosis of mixed states. The knowledge of the clinical features of the mixed states and of the symptoms of the "mixity" of mood disorders is crucial: to mis-diagnose or mis-treat patients with these symptoms may increase the suicide risk and make worse the evolution of mood disorders going to the dysphoric state. This study is the second validation study of the "G.T. MSRS" rating scale, in order to demonstrate its usefullness.

  10. Structural characterization of O- and C-glycosylating variants of the landomycin glycosyltransferase LanGT2.

    Science.gov (United States)

    Tam, Heng Keat; Härle, Johannes; Gerhardt, Stefan; Rohr, Jürgen; Wang, Guojun; Thorson, Jon S; Bigot, Aurélien; Lutterbeck, Monika; Seiche, Wolfgang; Breit, Bernhard; Bechthold, Andreas; Einsle, Oliver

    2015-02-23

    The structures of the O-glycosyltransferase LanGT2 and the engineered, C-C bond-forming variant LanGT2S8Ac show how the replacement of a single loop can change the functionality of the enzyme. Crystal structures of the enzymes in complex with a nonhydrolyzable nucleotide-sugar analogue revealed that there is a conformational transition to create the binding sites for the aglycon substrate. This induced-fit transition was explored by molecular docking experiments with various aglycon substrates. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  11. Characterization of the env gene and long terminal repeat of molecularly cloned Friend mink cell focus-inducing virus DNA.

    OpenAIRE

    Adachi, A; Sakai, K; Kitamura, N; Nakanishi, S; Niwa, O; Matsuyama, M; Ishimoto, A

    1984-01-01

    The highly oncogenic erythroleukemia-inducing Friend mink cell focus-inducing (MCF) virus was molecularly cloned in phage lambda gtWES.lambda B, and the DNA sequences of the env gene and the long terminal repeat were determined. The nucleotide sequences of Friend MCF virus and Friend spleen focus-forming virus were quite homologous, supporting the hypothesis that Friend spleen focus-forming virus might be generated via Friend MCF virus from an ecotropic Friend virus mainly by some deletions. ...

  12. CRISPR/Cas9-Assisted Transformation-Efficient Reaction (CRATER) for Near-Perfect Selective Transformation

    Science.gov (United States)

    Rothschild, Lynn J.; Greenberg, Daniel T.; Takahashi, Jack R.; Thompson, Kirsten A.; Maheshwari, Akshay J.; Kent, Ryan E.; McCutcheon, Griffin; Shih, Joseph D.; Calvet, Charles; Devlin, Tyler D.; hide

    2015-01-01

    The CRISPR (Clustered, Regularly Interspaced, Short Palindromic Repeats)/Cas9 system has revolutionized genome editing by providing unprecedented DNA-targeting specificity. Here we demonstrate that this system can be also applied in vitro to fundamental cloning steps to facilitate efficient plasmid selection for transformation and selective gene insertion into plasmid vectors by cleaving unwanted plasmid byproducts with a single-guide RNA (sgRNA)-Cas9 nuclease complex. Using fluorescent and chromogenic proteins as reporters, we demonstrate that CRISPR/Cas9 cleavage excludes multiple plasmids as well as unwanted ligation byproducts resulting in an unprecedented increase in the transformation success rate from approximately 20% to nearly 100%. Thus, this CRISPR/Cas9-Assisted Transformation-Efficient Reaction (CRATER) protocol is a novel, inexpensive, and convenient application to conventional molecular cloning to achieve near-perfect selective transformation.

  13. Elastic collisions of classical point particles on a finite frictionless linear track with perfectly reflecting endpoints

    Science.gov (United States)

    DeLuca, R.

    2006-03-01

    Repeated elastic collisions of point particles on a finite frictionless linear track with perfectly reflecting endpoints are considered. The problem is analysed by means of an elementary linear algebra approach. It is found that, starting with a state consisting of a projectile particle in motion at constant velocity and a target particle at rest in a fixed known position, the points at which collisions occur on track, when plotted versus progressive numerals, corresponding to the collisions themselves, show periodic patterns for a rather large choice of values of the initial position x(0) and on the mass ratio r. For certain values of these parameters, however, only regular behaviour over a large number of collisions is detected.

  14. Inhomogeneous generalizations of Bianchi type VIh models with perfect fluid

    Science.gov (United States)

    Roy, S. R.; Prasad, A.

    1991-07-01

    Inhomogeneous universes admitting an Abelian G2 of isometry and filled with perfect fluid have been derived. These contain as special cases exact homogeneous universes of Bianchi type VIh. Many of these universes asymptotically tend to homogeneous Bianchi VIh universes. The models have been discussed for their physical and kinematical behaviors.

  15. Gauge freedom in perfect fluid spatially homogeneous spacetimes

    International Nuclear Information System (INIS)

    Jantzen, R.T.

    1983-01-01

    The class of reference systems compatible with the symmetry of a spatially homogeneous perfect fluid spacetime is discussed together with the associated class of symmetry adapted comoving ADM frames (or computational frames). The fluid equations of motion are related to the four functions on the space of fluid flow lines discovered by Taub and which characterize an isentropic flow. (Auth.)

  16. Perfect Worlds : Utopian Fiction in China and the West

    NARCIS (Netherlands)

    Fokkema, Douwe

    2011-01-01

    Perfect Worlds biedt een uitgebreide historische analyse van utopische verhalen in de Chinese en Euro-Amerikaanse traditie. Aan bod komen onder meer de kritiek van Thomas More op Plato, de Europese oriëntalistische speurtocht naar utopieën in China en Chinese schrijvers die hun confucianistische

  17. Perfect Worlds : Utopian Fiction in China and the West

    NARCIS (Netherlands)

    Fokkema, Douwe

    2011-01-01

    Perfect Worlds biedt een uitgebreide historische analyse van utopische verhalen in de Chinese en Euro-Amerikaanse traditie. Verschillende hoofdstukken gaan onder meer in op de kritiek van Thomas More op Plato, de Europese oriëntalistische speurtocht naar utopieën in China, Dostoevsky’s reactie op

  18. Hyper-Achievement, Perfection, and College Student Resilience

    Science.gov (United States)

    Eells, Gregory T.

    2017-01-01

    Over the past decade, there has been considerable attention given to college students' experience of pressure to pursue perfection through hyper-achievement and the psychological and emotional toll this process takes on them. The popular press has highlighted this phenomenon and raised specific questions about some of the related consequences like…

  19. Cognitive Learning Styles: Can You Engineer a "Perfect" Match?

    Science.gov (United States)

    Khuzzan, Sharifah Mazlina Syed; Goulding, Jack Steven

    2016-01-01

    Education and training is widely acknowledged as being one of the key factors for leveraging organisational success. However, it is equally acknowledged that skills development and the acquisition of learning through managed cognitive approaches has yet to provide a "perfect" match. Whilst it is argued that an ideal learning scenario…

  20. The Perfect Storm--Genetic Engineering, Science, and Ethics

    Science.gov (United States)

    Rollin, Bernard E.

    2014-01-01

    Uncertainty about ethics has been a major factor in societal rejection of biotechnology. Six factors help create a societal "perfect storm" regarding ethics and biotechnology: Social demand for ethical discussion; societal scientific illiteracy; poor social understanding of ethics; a "Gresham's Law for Ethics;" Scientific…

  1. The Perfect Storm—Genetic Engineering, Science, and Ethics

    Science.gov (United States)

    Rollin, Bernard E.

    2014-02-01

    Uncertainty about ethics has been a major factor in societal rejection of biotechnology. Six factors help create a societal "perfect storm" regarding ethics and biotechnology: Social demand for ethical discussion; societal scientific illiteracy; poor social understanding of ethics; a "Gresham's Law for Ethics;" Scientific Ideology; vested interests dominating ethical discussion. How this can be remedied is discussed.

  2. Overemphasis on Perfectly Competitive Markets in Microeconomics Principles Textbooks

    Science.gov (United States)

    Hill, Roderick; Myatt, Anthony

    2007-01-01

    Microeconomic principles courses focus on perfectly competitive markets far more than other market structures. The authors examine five possible reasons for this but find none of them sufficiently compelling. They conclude that textbook authors should place more emphasis on how economists select appropriate models and test models' predictions…

  3. Helicity and other conservation laws in perfect fluid motion

    Science.gov (United States)

    Serre, Denis

    2018-03-01

    In this review paper, we discuss helicity from a geometrical point of view and see how it applies to the motion of a perfect fluid. We discuss its relation with the Hamiltonian structure, and then its extension to arbitrary space dimensions. We also comment about the existence of additional conservation laws for the Euler equation, and its unlikely integrability in Liouville's sense.

  4. A short note on nearly perfect maps of locales | Razafindrakoto ...

    African Journals Online (AJOL)

    We characterise compact locales in terms of nearly perfect maps. We show in particular that these maps are the natural pointfree version of Bourbaki's proper maps - when defined via any ultrafillter - and that they extend Herrlich's notion of nearly closed sublocales [10]. Mathematics Subject Classication (2010): 06A15, ...

  5. Indefinite and Continuative Interpretations of the English Present Perfect

    Directory of Open Access Journals (Sweden)

    Katarina Dea Žetko

    2005-06-01

    Full Text Available The objective of our paper is to demonstrate that the English present perfect is not by inherent meaning either indefinite or continuative. Notions like indefinite and continuative are contextdependent interpretations of whole constructions and their broader context. However, continuative interpretation can also be triggered by certain adverbials, negative constructions and verbs in the progressive form. But, even these factors do not always guarantee continuative interpretations. Construction, continuative meaning can be cancelled by the context in a broader sense, this fact being a proof that this meaning is merely an implicature. We will demonstrate how different factors interact and trigger either indefinite or continuative interpretations which are not inherent in the present perfect itself. Our paper will attempt to provide sufficient evidence that there is no indefinite/continuative distinction in the English present perfect, the inherent meaning or function of the present perfect is merely to locate the situation somewhere within a period that starts before the time of utterance and leads up to it.

  6. Robust Secure Authentication and Data Storage with Perfect Secrecy

    Directory of Open Access Journals (Sweden)

    Sebastian Baur

    2018-04-01

    Full Text Available We consider an authentication process that makes use of biometric data or the output of a physical unclonable function (PUF, respectively, from an information theoretical point of view. We analyse different definitions of achievability for the authentication model. For the secrecy of the key generated for authentication, these definitions differ in their requirements. In the first work on PUF based authentication, weak secrecy has been used and the corresponding capacity regions have been characterized. The disadvantages of weak secrecy are well known. The ultimate performance criteria for the key are perfect secrecy together with uniform distribution of the key. We derive the corresponding capacity region. We show that, for perfect secrecy and uniform distribution of the key, we can achieve the same rates as for weak secrecy together with a weaker requirement on the distribution of the key. In the classical works on PUF based authentication, it is assumed that the source statistics are known perfectly. This requirement is rarely met in applications. That is why the model is generalized to a compound model, taking into account source uncertainty. We also derive the capacity region for the compound model requiring perfect secrecy. Additionally, we consider results for secure storage using a biometric or PUF source that follow directly from the results for authentication. We also generalize known results for this problem by weakening the assumption concerning the distribution of the data that shall be stored. This allows us to combine source compression and secure storage.

  7. The periphrastic perfect of Old Persian revisited (slides) [Dataset

    NARCIS (Netherlands)

    Bavant, M.J.J.

    2011-01-01

    The voice of the periphrastic perfect of Old Persian has long been a controversial issue. This document is a slide set to present the matter. It illustrates the contents of an article on the same theme: "Retour sur le parfait périphrastique du vieux perse".

  8. Unity and Duality in Barack Obama's "A More Perfect Union"

    Science.gov (United States)

    Terrill, Robert E.

    2009-01-01

    Faced with a racialized political crisis that threatened to derail his campaign to become the first African American president of the United States, Barack Obama delivered a speech on race titled "A More Perfect Union." He begins by portraying himself as an embodiment of double consciousness, but then invites his audience to share his…

  9. A linear construction of perfect secret sharing schemes

    NARCIS (Netherlands)

    Dijk, van M.; Santis, De A.

    1995-01-01

    In this paper, we generalize the vector space construction due to Brickell [5]. This generalization, introduced by Bertilsson [1], leads to perfect secret sharing schemes with rational information rates in which the secret can be computed efficiently by each qualified group. A one to one

  10. Tie-breaking in games of perfect information

    DEFF Research Database (Denmark)

    Tranæs, Torben

    1998-01-01

    The paper suggests that ties in an extensive form game have strategic implications if they represent credible threats or promises. We consider a subset of subgame-perfect Nash equilibria obtained by breaking ties according to their strategic implications, and show that the subset is nonempty for ...

  11. Perfect 2-colorings of the generalized Petersen graph

    Indian Academy of Sciences (India)

    It is obvious that GP(n, k) is a 3-regular connected graph. DEFINITION 2.2 ... vertex of color i, the number of its neighbors of color j is equal to aij . ... By the given conditions, we can see that a parameter matrix of a perfect 2-coloring of. GP(n, k) ...

  12. An improved perfectly matched layer for the eigenmode expansion technique

    DEFF Research Database (Denmark)

    Gregersen, Niels; Mørk, Jesper

    2008-01-01

    be suppressed by introducing a perfectly matched layer (PML) using e.g. complex coordinate stretching of the cylinder radius. However, the traditional PML suffers from an artificial field divergence limiting its usefulness. We show that the choice of a constant cylinder radius leads to mode profiles...

  13. An improved perfectly matched layer in the eigenmode expansion technique

    DEFF Research Database (Denmark)

    Gregersen, Niels; Mørk, Jesper

    2008-01-01

    When employing the eigenmode expansion technique (EET), parasitic reflections at the boundary of the computational domain can be suppressed by introducing a perfectly matched layer (PML). However, the traditional PML, suffers from an artificial field divergence limiting its usefulness. We propose...

  14. Perfect Power Prototype for Illinois Institute of Technology

    Energy Technology Data Exchange (ETDEWEB)

    Shahidehpour, Mohammad [Illinois Inst. Of Technology, Chicago, IL (United States)

    2014-09-30

    Starting in October 2008, Illinois Institute of Technology (IIT), in collaboration with over 20 participating members, led an extensive effort to develop, demonstrate, promote, and commercialize a microgrid system and offer supporting technologies that will achieve Perfect Power at the main campus of IIT. A Perfect Power system, as defined by the Galvin Electricity Initiative (GEI), is a system that cannot fail to meet the electric needs of the individual end-user. The Principle Investigator of this Perfect Power project was Dr. Mohammad Shahidehpour, Director of the Robert W. Galvin Center for Electricity Innovation at IIT. There were six overall objectives of the Perfect Power project: (1) Demonstrate the higher reliability introduced by the microgrid system at IIT; (2) Demonstrate the economics of microgrid operations; (3) Allow for a decrease of fifty percent (50%) of grid electricity load; (4) Create a permanent twenty percent (20%) decrease in peak load from 2007 level; (5) Defer planned substation through load reduction; (6) Offer a distribution system design that can be replicated in urban communities.

  15. Generalized magneto-thermoviscoelasticity in a perfectly conducting ...

    Indian Academy of Sciences (India)

    on the theory of generalized thermoelastic diffusion with one relaxation time. ... cavity is taken to be traction free and subjected to both heating and external constant ... problems on wave propagation in a linear viscoelas- ... Let us consider a perfect electric conductor medium ... The energy equation in the context of general-.

  16. The Arabidopsis Family GT43 Glycosyltransferases Form Two Functionally Nonredundant Groups Essential for the Elongation of Glucuronoxylan Backbone

    Science.gov (United States)

    There exist four members of family GT43 glycosyltransferases in the Arabidopsis (Arabidopsis thaliana) genome, and mutations of two of them, IRX9 and IRX14, have previously been shown to cause a defect in glucuronoxylan (GX) biosynthesis. However, it is currently unknown whether ...

  17. Første fælles nordiske monitorering af kost, fysisk aktivitet og overvægt

    DEFF Research Database (Denmark)

    Fagt, Sisse; Rasmussen, Lone Banke; Trolle, Ellen

    2012-01-01

    Som en vigtig del af den nordiske handlingsplan for bedre sundhed og livskvalitet gennem kost og fysisk aktivitet har Nordisk Ministerråd besluttet at udvikle og gennemføre en fælles nordisk undersøgelse af kost, fysisk aktivitet og overvægt. Den første monitorering gennemførtes i Norge, Sverige,...

  18. MTP -493G/T gene polymorphism is associated with steatosis in hepatitis C-infected patients

    Energy Technology Data Exchange (ETDEWEB)

    Siqueira, E.R.F. [Departamento de Gastroenterologia, LIM-07, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP (Brazil); Departamento de Bioquímica, Faculdade de Medicina, Universidade de Pernambuco, Recife, PE (Brazil); Departamento de Gastroenterologia, Faculdade de Medicina, Universidade de Pernambuco, Recife, PE (Brazil); Oliveira, C.P.M.S. [Departamento de Gastroenterologia, LIM-07, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP (Brazil); Correa-Giannella, M.L. [Laboratório de Endocrinologia Celular e Molecular, LIM-25, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP (Brazil); Stefano, J.T. [Departamento de Gastroenterologia, LIM-07, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP (Brazil); Cavaleiro, A.M.; Fortes, M.A.H.Z. [Laboratório de Endocrinologia Celular e Molecular, LIM-25, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP (Brazil); Muniz, M.T.C.; Silva, F.S. [Departamento de Bioquímica, Faculdade de Medicina, Universidade de Pernambuco, Recife, PE (Brazil); Pereira, L.M.M.B. [Departamento de Gastroenterologia, Faculdade de Medicina, Universidade de Pernambuco, Recife, PE (Brazil); Instituto do Fígado de Pernambuco, Recife, PE (Brazil); Carrilho, F.J. [Departamento de Gastroenterologia, LIM-07, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP (Brazil)

    2011-12-09

    The reduction of hepatic microsomal transfer protein (MTP) activity results in fatty liver, worsening hepatic steatosis and fibrosis in chronic hepatitis C (CHC). The G allele of the MTP gene promoter, -493G/T, has been associated with lower transcriptional activity than the T allele. We investigated this association with metabolic and histological variables in patients with CHC. A total of 174 untreated patients with CHC were genotyped for MTP -493G/T by direct sequencing using PCR. All patients were negative for markers of Wilson's disease, hemochromatosis and autoimmune diseases and had current and past daily alcohol intake lower than 100 g/week. The sample distribution was in Hardy-Weinberg equilibrium. Among subjects with genotype 1, 56.8% of the patients with fibrosis grade 3+4 presented at least one G allele versus 34.3% of the patients with fibrosis grade 1+2 (OR = 1.8; 95%CI = 1.3-2.3). Logistic regression analysis with steatosis as the dependent variable identified genotypes GG+GT as independent protective factors against steatosis (OR = 0.4, 95%CI = 0.2-0.8; P = 0.01). The results suggest that the presence of the G allele of MTP -493G/T associated with lower hepatic MTP expression protects against steatosis in our CHC patients.

  19. DNMT3B -579 G>T Promoter Polymorphism and the Risk of Gastric Cancer in the West of Iran.

    Science.gov (United States)

    Ahmadi, Kulsom; Soleimani, Azam; Irani, Shiva; Kiani, Aliasghar; Ghanadi, Kourosh; Noormohamadi, Zahra; Sakinejad, Foroozan

    2018-06-01

    Many studies have suggested that modulation of DNMT3B function caused by single nucleotide polymorphisms of the DNMT3B promoter region may underlie the susceptibility to various cancers such as tumors of the digestive system. The aim of this study was to investigate the effect of -579 G>T polymorphism in the promoter of the DNMT3B gene on risk of gastric cancer in a population from West Iran. We conducted a case-control study in 100 gastric cancer patients and 112 cancer-free controls to assess the correlation between DNMT3B -579 G>T (rs1569686) polymorphism and the risk of gastric cancer. Detection of genotypes of DNMT3B G39179T polymorphism was analyzed by PCR-RFLP. There was no significant difference in the distribution of DNMT3B -579 G>T genotypes between the cases and controls. However, in the stratified analysis by clinicopathological characteristic types, we found that statistically, the risk susceptibility to gastric cancer was significantly associated with tumor grade II and GT/TT genotype of patients, compared to patients having GG genotype, (OR = 5.4737, 95% CI = 1.4746. 20.3184, P = 0.01). Our study suggested that the -579 T allele may increase the relative risk for the progression of clinicopathological characteristic of tumor grade of gastric cancer patients.

  20. Validation of the Actigraph GT3X and ActivPAL Accelerometers for the Assessment of Sedentary Behavior

    Science.gov (United States)

    Kim, Youngdeok; Barry, Vaughn W.; Kang, Minsoo

    2015-01-01

    This study examined (a) the validity of two accelerometers (ActiGraph GT3X [ActiGraph LLC, Pensacola, FL, USA] and activPAL [PAL Technologies Ltd., Glasgow, Scotland]) for the assessment of sedentary behavior; and (b) the variations in assessment accuracy by setting minimum sedentary bout durations against a proxy for direct observation using an…

  1. MTP -493G/T gene polymorphism is associated with steatosis in hepatitis C-infected patients

    International Nuclear Information System (INIS)

    Siqueira, E.R.F.; Oliveira, C.P.M.S.; Correa-Giannella, M.L.; Stefano, J.T.; Cavaleiro, A.M.; Fortes, M.A.H.Z.; Muniz, M.T.C.; Silva, F.S.; Pereira, L.M.M.B.; Carrilho, F.J.

    2011-01-01

    The reduction of hepatic microsomal transfer protein (MTP) activity results in fatty liver, worsening hepatic steatosis and fibrosis in chronic hepatitis C (CHC). The G allele of the MTP gene promoter, -493G/T, has been associated with lower transcriptional activity than the T allele. We investigated this association with metabolic and histological variables in patients with CHC. A total of 174 untreated patients with CHC were genotyped for MTP -493G/T by direct sequencing using PCR. All patients were negative for markers of Wilson's disease, hemochromatosis and autoimmune diseases and had current and past daily alcohol intake lower than 100 g/week. The sample distribution was in Hardy-Weinberg equilibrium. Among subjects with genotype 1, 56.8% of the patients with fibrosis grade 3+4 presented at least one G allele versus 34.3% of the patients with fibrosis grade 1+2 (OR = 1.8; 95%CI = 1.3-2.3). Logistic regression analysis with steatosis as the dependent variable identified genotypes GG+GT as independent protective factors against steatosis (OR = 0.4, 95%CI = 0.2-0.8; P = 0.01). The results suggest that the presence of the G allele of MTP -493G/T associated with lower hepatic MTP expression protects against steatosis in our CHC patients

  2. Do Musicians with Perfect Pitch Have More Autism Traits than Musicians without Perfect Pitch? An Empirical Study

    DEFF Research Database (Denmark)

    Dohn, Anders; Garza-Villarreal, Eduardo A.; Heaton, Pamela

    2012-01-01

    Perfect pitch, also known as absolute pitch (AP), refers to the rare ability to identify or produce a musical tone correctly without the benefit of an external reference. AP is often considered to reflect musical giftedness, but it has also been associated with certain disabilities due to increas...

  3. GT-WGS: an efficient and economic tool for large-scale WGS analyses based on the AWS cloud service.

    Science.gov (United States)

    Wang, Yiqi; Li, Gen; Ma, Mark; He, Fazhong; Song, Zhuo; Zhang, Wei; Wu, Chengkun

    2018-01-19

    Whole-genome sequencing (WGS) plays an increasingly important role in clinical practice and public health. Due to the big data size, WGS data analysis is usually compute-intensive and IO-intensive. Currently it usually takes 30 to 40 h to finish a 50× WGS analysis task, which is far from the ideal speed required by the industry. Furthermore, the high-end infrastructure required by WGS computing is costly in terms of time and money. In this paper, we aim to improve the time efficiency of WGS analysis and minimize the cost by elastic cloud computing. We developed a distributed system, GT-WGS, for large-scale WGS analyses utilizing the Amazon Web Services (AWS). Our system won the first prize on the Wind and Cloud challenge held by Genomics and Cloud Technology Alliance conference (GCTA) committee. The system makes full use of the dynamic pricing mechanism of AWS. We evaluate the performance of GT-WGS with a 55× WGS dataset (400GB fastq) provided by the GCTA 2017 competition. In the best case, it only took 18.4 min to finish the analysis and the AWS cost of the whole process is only 16.5 US dollars. The accuracy of GT-WGS is 99.9% consistent with that of the Genome Analysis Toolkit (GATK) best practice. We also evaluated the performance of GT-WGS performance on a real-world dataset provided by the XiangYa hospital, which consists of 5× whole-genome dataset with 500 samples, and on average GT-WGS managed to finish one 5× WGS analysis task in 2.4 min at a cost of $3.6. WGS is already playing an important role in guiding therapeutic intervention. However, its application is limited by the time cost and computing cost. GT-WGS excelled as an efficient and affordable WGS analyses tool to address this problem. The demo video and supplementary materials of GT-WGS can be accessed at https://github.com/Genetalks/wgs_analysis_demo .

  4. Repeatability of Cryogenic Multilayer Insulation

    Science.gov (United States)

    Johnson, W. L.; Vanderlaan, M.; Wood, J. J.; Rhys, N. O.; Guo, W.; Van Sciver, S.; Chato, D. J.

    2017-12-01

    Due to the variety of requirements across aerospace platforms, and one off projects, the repeatability of cryogenic multilayer insulation (MLI) has never been fully established. The objective of this test program is to provide a more basic understanding of the thermal performance repeatability of MLI systems that are applicable to large scale tanks. There are several different types of repeatability that can be accounted for: these include repeatability between identical blankets, repeatability of installation of the same blanket, and repeatability of a test apparatus. The focus of the work in this report is on the first two types of repeatability. Statistically, repeatability can mean many different things. In simplest form, it refers to the range of performance that a population exhibits and the average of the population. However, as more and more identical components are made (i.e. the population of concern grows), the simple range morphs into a standard deviation from an average performance. Initial repeatability testing on MLI blankets has been completed at Florida State University. Repeatability of five Glenn Research Center (GRC) provided coupons with 25 layers was shown to be +/- 8.4% whereas repeatability of repeatedly installing a single coupon was shown to be +/- 8.0%. A second group of 10 coupons has been fabricated by Yetispace and tested by Florida State University, the repeatability between coupons has been shown to be +/- 15-25%. Based on detailed statistical analysis, the data has been shown to be statistically significant.

  5. Present activity of the feasibility study of HTGR-GT system

    International Nuclear Information System (INIS)

    Muto, Y.; Miyamoto, Y.; Shiozawa, S.

    2001-01-01

    In JAERI a feasibility study of the High Temperature Gas-cooled Reactor-Gas Turbine (HTGR-GT) system has been carried out since January, 1997 as an assigned work by the Science and Technology Agency. The study aims at obtaining a promising concept of HTGR-GT system that yields a high thermal efficiency and at the same time is economically competitive. Designs of a few candidate systems will be undertaken and their power generation costs will be evaluated in parallel with design works, some experimental works such as the fabrication of a plate-fin type heat exchanger core and material tests will be carried out. The study will be continued till 2000 fiscal year. In 1997 fiscal year, a preliminary design of a direct cycle plant of 600 MWt was developed. A reactor inlet gas temperature of 460 deg. C, a reactor outlet gas temperature of 850 deg. C and a helium gas pressure of 6MPa were selected. Some advanced technologies were adopted such as a monolithic fuel compact and a control rod sheath made of carbon/carbon composite material. They were very effective to enhance the heat transfer of fuel and to reduce the core bypass flow. As a result, a power density of 6MW/m 3 and the maximum burnup of 10 5 MWD/ton were achieved. A single-shaft horizontal turbomachine of 3600 rpm was selected to ease the mechanical design of the rotor supported by magnetic bearings. The turbine, two compressors, a generator and six units of intercooler were placed in a turbine vessel, Plate-fin type recuperator and precooler are installed in a vertical heat exchanger vessel. By this design, a net thermal efficiency of 45.7% is expected to be achieved. To develop a high performance plate-fin recuperator, a core model of W200 mm x L200 mm x H200 mm with small fin size of 1.15 mm height was fabricated and as a result of tests, leak tightness, component strength and bonding appearance were found to be satisfactory. In 1998 fiscal year, a design of a direct cycle plant of 300 MWt is undertaken. The

  6. Conformational analysis of GT1B ganglioside and its interaction with botulinum neurotoxin type B: a study by molecular modeling and molecular dynamics.

    Science.gov (United States)

    Venkateshwari, Sureshkumar; Veluraja, Kasinadar

    2012-01-01

    The conformational property of oligosaccharide GT1B in aqueous environment was studied by molecular dynamics (MD) simulation using all-atom model. Based on the trajectory analysis, three prominent conformational models were proposed for GT1B. Direct and water-mediated hydrogen bonding interactions stabilize these structures. The molecular modeling and 15 ns MD simulation of the Botulinum Neuro Toxin/B (BoNT/B) - GT1B complex revealed that BoNT/B can accommodate the GT1B in the single binding mode. Least mobility was seen for oligo-GT1B in the binding pocket. The bound conformation of GT1B obtained from the MD simulation of the BoNT/B-GT1B complex bear a close conformational similarity with the crystal structure of BoNT/A-GT1B complex. The mobility noticed for Arg 1268 in the dynamics was accounted for its favorable interaction with terminal NeuNAc. The internal NeuNAc1 tends to form 10 hydrogen bonds with BoNT/B, hence specifying this particular site as a crucial space for the therapeutic design that can restrict the pathogenic activity of BoNT/B.

  7. An exergoeconomic investigation of waste heat recovery from the Gas Turbine-Modular Helium Reactor (GT-MHR) employing an ammonia–water power/cooling cycle

    International Nuclear Information System (INIS)

    Zare, V.; Mahmoudi, S.M.S.; Yari, M.

    2013-01-01

    A detailed exergoeconomic analysis is performed for a combined cycle in which the waste heat from the Gas Turbine-Modular Helium Reactor (GT-MHR) is recovered by an ammonia–water power/cooling cogeneration system. Parametric investigations are conducted to evaluate the effects of decision variables on the performances of the GT-MHR and combined cycles. The performances of these cycles are then optimized from the viewpoints of first law, second law and exergoeconomics. It is found that, combining the GT-MHR with ammonia–water cycle not only enhances the first and second law efficiencies of the GT-MHR, but also it improves the cycle performance from the exergoeconomic perspective. The results show that, when the optimization is based on the exergoeconomics, the unit cost of products is reduced by 5.4% in combining the two mentioned cycles. This is achieved with a just about 1% increase in total investment cost rate since the helium mass flow in the combined cycle is lower than that in the GT-MHR alone. - Highlights: • Application of exergetic cost theory to the combined GT-MHR/ammonia–water cycle. • Enhanced exergoeconomic performance for the combined cycle compared to the GT-MHR. • Comparable investment costs for the combined cycle and the GT-MHR alone

  8. Wages and employment in a repeated game with revenue fluctuations

    DEFF Research Database (Denmark)

    Schultz, Christian

    1997-01-01

    Empirical investigations suggests that the real wage is surprisingly flat over the business cycle. This paper analyses a repeated game between a union and a firm which can contribute to explaining the flat wage. The parties cannot enter binding contracts, and revenue is fluctuating. The paper...... focuses on the best subgame-perfect equilibrium among those sharing the expected surplus in given fixed shares - e.g. equal shares. It is shown that (for moderate discount factors) this equilibrium has a more counter-cyclical wage, than what would be the case if the parties shared the surplus in each...

  9. Repeat Customer Success in Extension

    Science.gov (United States)

    Bess, Melissa M.; Traub, Sarah M.

    2013-01-01

    Four multi-session research-based programs were offered by two Extension specialist in one rural Missouri county. Eleven participants who came to multiple Extension programs could be called "repeat customers." Based on the total number of participants for all four programs, 25% could be deemed as repeat customers. Repeat customers had…

  10. 78 FR 65594 - Vehicular Repeaters

    Science.gov (United States)

    2013-11-01

    ... coordinators estimate the effect on coordination fees? Does the supposed benefit that mobile repeater stations... allow the licensing and operation of vehicular repeater systems and other mobile repeaters by public... email: [email protected] or phone: 202-418- 0530 or TTY: 202-418-0432. For detailed instructions for...

  11. Op zoek naar de perfecte match in vrijwilligersland

    Directory of Open Access Journals (Sweden)

    Els van Gilst

    2015-06-01

    Full Text Available Finding the perfect volunteer matchOrganizations that are (partially staffed by volunteers in the Netherlands are experiencing a growing need for volunteers. This relates to stricter laws and regulations, the changing deployment of volunteers and reforms in the care system (Bekkers & Boezeman, 2009; Devilee, 2005; MOVISIE, 2014; Rutte & Samsom, 2012.Volunteer centres can form part of the solution to the growing demand for volunteers. There are about 240 volunteer centres in the Netherlands. They promote volunteering and provide information, training, advice and support in this area. In addition, they play an active role as brokers in bringing together supply (volunteers and demand (volunteer-involving organizations. This intermediary role is often the core business of volunteer centres (Ploegmakers, Merkus & Terpstra, 2011; Terpstra, Ploegmakers & van Laar, 2008.The success of volunteer brokerage remains relatively limited, however. Offline brokerage (at the office of the volunteer centre is in about half of the cases successful. This falls to 37 percent for online brokerage. Volunteer brokerage is classed as successful when a volunteer is placed at an organization for a short-term project or a period of three months (Ploegmakers et al., 2011.Literature research (Van Gilst, Schalk, Garretsen & Van de Goor, 2011 was carried out to determine how the results of volunteer brokerage can be improved. The motivation and feelings of pride and respect on the part of a volunteer are found to be important for the level of satisfaction and willingness to keep on volunteering in both the short term and the long term.This article examines how success factors such as motivation, pride and respect can be incorporated into the daily brokerage practices of volunteer centres. Two research questions are central to this article:1. How does volunteer brokerage occur in practice?2. When and how can success factors for matching volunteers and organizations (partially

  12. On a ''conformal'' perfect fluid in the classical vacuum

    International Nuclear Information System (INIS)

    Culetu, H.

    1993-02-01

    A possible existence of a conformal perfect fluid in the classical vacuum is investigated in this letter. It is shown, contrary to Madsen's opinion, that the scalar field stress tensor acquires a perfect fluid form even with a nonminimal coupling (ξ = 1/6) in the Einstein Lagrangian, provided the geometry is the Lorentzian analogue of the Euclidean Hawking wormhole. In addition, our T μν equals (up to a constant factor) the vacuum expectation value of the Fulling stress tensor for a massless scalar field and Visser's one concerning transversible wormholes. On the other side of the light cone, there is a coordinate system (the dimensionally reduced Witten bubble) where the stress tensor becomes diagonal. (author). 13 refs

  13. Perfect commuting-operator strategies for linear system games

    Science.gov (United States)

    Cleve, Richard; Liu, Li; Slofstra, William

    2017-01-01

    Linear system games are a generalization of Mermin's magic square game introduced by Cleve and Mittal. They show that perfect strategies for linear system games in the tensor-product model of entanglement correspond to finite-dimensional operator solutions of a certain set of non-commutative equations. We investigate linear system games in the commuting-operator model of entanglement, where Alice and Bob's measurement operators act on a joint Hilbert space, and Alice's operators must commute with Bob's operators. We show that perfect strategies in this model correspond to possibly infinite-dimensional operator solutions of the non-commutative equations. The proof is based around a finitely presented group associated with the linear system which arises from the non-commutative equations.

  14. Novel beam bunching methods by perfect crystals and electromagnetic means

    International Nuclear Information System (INIS)

    Rauch, H.

    1985-01-01

    The use of perfect crystals for installing new neutron small-angle scattering cameras provides advantages for measurements in the small Q-range and for real-time experiments. A neutron resonator is proposed which is based on the combination of perfect crystal back-reflections in Zeman energy splitting. The neutron magnetic resonance system in combination with gated crystals can act as a pumping unit for neutrons and as a new pulse-shaping unit. It is shown how travelling magnetic waves can act as powerful neutron bunching units. The achievable velocity changes are around 5 m/s and, therefore, by a factor of 100 larger than in the case of neutron magnetic resonance systems. The advantage of expanding potentials for focusing neutrons from a source with a long pulse duration becomes obvious. Real gain factors higher than 10 are expected for properly designed systems. (author)

  15. Thermodynamics of perfect fluids from scalar field theory

    CERN Document Server

    Ballesteros, Guillermo; Pilo, Luigi

    2016-01-01

    The low-energy dynamics of relativistic continuous media is given by a shift-symmetric effective theory of four scalar fields. These scalars describe the embedding in spacetime of the medium and play the role of Stuckelberg fields for spontaneously broken spatial and time translations. Perfect fluids are selected imposing a stronger symmetry group or reducing the field content to a single scalar. We explore the relation between the field theory description of perfect fluids to thermodynamics. By drawing the correspondence between the allowed operators at leading order in derivatives and the thermodynamic variables, we find that a complete thermodynamic picture requires the four Stuckelberg fields. We show that thermodynamic stability plus the null energy condition imply dynamical stability. We also argue that a consistent thermodynamic interpretation is not possible if any of the shift symmetries is explicitly broken.

  16. Tunable enhanced optical absorption of graphene using plasmonic perfect absorbers

    Energy Technology Data Exchange (ETDEWEB)

    Cai, Yijun [Institute of Optoelectronic Technology, Department of Electronic Engineering, Xiamen University, Xiamen 361005 (China); Institute of Electromagnetics and Acoustics, Department of Electronic Science, Xiamen University, Xiamen 361005 (China); Zhu, Jinfeng, E-mail: nanoantenna@hotmail.com [Institute of Electromagnetics and Acoustics, Department of Electronic Science, Xiamen University, Xiamen 361005 (China); Liu, Qing Huo [Department of Electrical and Computer Engineering, Duke University, Durham, North Carolina 27708 (United States)

    2015-01-26

    Enhancement and manipulation of light absorption in graphene is a significant issue for applications of graphene-based optoelectronic devices. In order to achieve this purpose in the visible region, we demonstrate a design of a graphene optical absorber inspired by metal-dielectric-metal metamaterial for perfect absorption of electromagnetic waves. The optical absorbance ratios of single and three atomic layer graphene are enhanced up to 37.5% and 64.8%, respectively. The graphene absorber shows polarization-dependence and tolerates a wide range of incident angles. Furthermore, the peak position and bandwidth of graphene absorption spectra are tunable in a wide wavelength range through a specific structural configuration. These results imply that graphene in combination with plasmonic perfect absorbers have a promising potential for developing advanced nanophotonic devices.

  17. Efficiency enhancement of GT-MHRs applied on ship propulsion plants

    Energy Technology Data Exchange (ETDEWEB)

    Ferreiro Garcia, Ramon, E-mail: ferreiro@udc.es [Dept. Industrial Engineering, University of A Coruna, ETSNM, C/Paseo de Ronda, 51, 15011 A Coruna (Spain); Carril, Jose Carbia; Catoira, Alberto DeMiguel; Romero Gomez, Javier [Dept. Energy and Propulsion, University of A Coruna ETSNM, C/Paseo de Ronda, 51, 15011 A Coruna (Spain)

    2012-09-15

    Highlights: Black-Right-Pointing-Pointer Efficient ship propulsion system powered by HTRs. Black-Right-Pointing-Pointer A conventional Rankine cycle renders high efficiency. Black-Right-Pointing-Pointer The intermediate heat exchanger isolates the nuclear reactor from the process heat application. Black-Right-Pointing-Pointer An intermediate heat exchanger allows the system to be built to non-nuclear standards. - Abstract: High temperature reactors including gas cooled fast reactors and gas turbine modular helium reactors (GT-MHR) may operate as electric power suppliers to be applied on ship propulsion plants. In such propulsion systems performance enhancement can be achieved at effective cost under safety conditions using alternative cycles to the conventional Brayton cycle. Mentioned improvements concern the implementation of an ultra supercritical Rankine cycle, in which water is used as working fluid. The proposed study is carried out in order to achieve performance enhancement on the basis of turbine temperature increasing. The helium cooled high temperature reactor supplies thermal energy to the Rankine cycle via an intermediate heat exchanger (IHE) under safety conditions. The results of the study show that the efficiency of the propulsion plant using a multi-reheat Rankine cycle is significantly improved (from actual 48% to more than 55%) while keeping safety standards.

  18. Benchmark calculation for GT-MHR using HELIOS/MASTER code package and MCNP

    International Nuclear Information System (INIS)

    Lee, Kyung Hoon; Kim, Kang Seog; Noh, Jae Man; Song, Jae Seung; Zee, Sung Quun

    2005-01-01

    The latest research associated with the very high temperature gas-cooled reactor (VHTR) is focused on the verification of a system performance and safety under operating conditions for the VHTRs. As a part of those, an international gas-cooled reactor program initiated by IAEA is going on. The key objectives of this program are the validation of analytical computer codes and the evaluation of benchmark models for the projected and actual VHTRs. New reactor physics analysis procedure for the prismatic VHTR is under development by adopting the conventional two-step procedure. In this procedure, a few group constants are generated through the transport lattice calculations using the HELIOS code, and the core physics analysis is performed by the 3-dimensional nodal diffusion code MASTER. We evaluated the performance of the HELIOS/MASTER code package through the benchmark calculations related to the GT-MHR (Gas Turbine-Modular Helium Reactor) to dispose weapon plutonium. In parallel, MCNP is employed as a reference code to verify the results of the HELIOS/MASTER procedure

  19. Evolution of the Power Conversion Unit Design of the GT-MHR

    International Nuclear Information System (INIS)

    Baxi, C.B.; Perez, E.; Shenoy, A.; Kostin, V.I.; Kodochigov, N.G.; Vasyaev, A.V.; Belov, S.E.; Golovko, V.F.

    2006-01-01

    General Atomics in the USA and Experimental Design Bureau of Machine Building (OKBM) in the Russian Federation are jointly developing a gas turbine modular helium reactor (GT-MHR). The 600 MW(t) reactor is cooled by helium at a pressure of 7 MPa. The power conversion unit (PCU) uses the reactor outlet temperature of 850 deg C in a direct Brayton cycle to achieve an efficiency of about 48%. The PCU consists of a gas turbine, a recuperator, a pre-cooler, a low-pressure compressor, an inter-cooler, and a high-pressure compressor. The turbo machine (TM), including the generator, is mounted on a single vertical shaft. The TM rotates at a speed of 4400 rpm. The asynchronous generator is connected to the turbine by a flexible coupling. The required grid frequency is achieved by a converter. All PCU components are enclosed in a single vessel. TM uses radial and axial electromagnetic bearings (EMB) for support. Catcher bearings (CB) are provided as redundant support for the TM rotor in case of EMBs failure. These design features were determined after a comprehensive study carried out over the last 10 years. This paper describes the evolution of the current PCU design and justification for the choices. (authors)

  20. Full load synthesis/design optimization of a hybrid SOFC-GT power plant

    International Nuclear Information System (INIS)

    Calise, F.; Dentice d' Accadia, M.; Vanoli, L.; Spakovsky, Michael R. von

    2007-01-01

    In this paper, the optimization of a hybrid solid oxide fuel cell-gas turbine (SOFC-GT) power plant is presented. The plant layout is based on an internal reforming SOFC stack; it also consists of a radial gas turbine, centrifugal compressors and plate-fin heat exchangers. In the first part of the paper, the bulk-flow model used to simulate the plant is presented. In the second part, a thermoeconomic model is developed by introducing capital cost functions. The whole plant is first simulated for a fixed configuration of the most important synthesis/design (S/D) parameters in order to establish a reference design configuration. Next a S/D optimization of the plant is carried out using a traditional single-level approach, based on a genetic algorithm. The optimization determined a set of S/D decision variable values with a capital cost significantly lower than that of the reference design, even though the net electrical efficiency for the optimal configuration was very close to that of the initial one. Furthermore, the optimization procedure dramatically reduced the SOFC active area and the compact heat exchanger areas

  1. Gabbroic lithologies of the dike-gabbro transition, Hole GT3A, Oman Drilling Project

    Science.gov (United States)

    Jesus, A. P. M.; Koepke, J.; Morishita, T.; Beinlich, A.; Johnson, K. T. M.; Greenberger, R. N.; Harris, M.; Michibayashi, K.; de Obeso, J. C.

    2017-12-01

    Hole GT3A intersects 400 m of oceanic crust providing unique insight into the dike-gabbro transition and the variability of the high level gabbros in the Samail ophiolite. Olivine gabbro and olivine bearing gabbro occur exclusively within the Upper Gabbro Sequence (16 % thickness; 111.02 m - 127.89 m) whereas oxide gabbro and disseminated oxide gabbro represent ca 5 % of the Lower Gabbro Sequence (233.84 m - 398.21 m). Gabbro with less than 1 vol. % olivine and oxide is the most common lithology in both Gabbro Sequences (10-13 %). Most gabbroic rocks were classified as "varitextured" due to textural and grain size macroscopic variations forming irregular domains/patches. Varitextured gabbros are medium-grained (1-5 mm), with seriate grain size distribution and subophitic/poikilitic to granular textural domains. Poikilitic domains comprise clinopyroxene with plagioclase chadacrysts, whereas in granular domains plagioclase interstices are filled by green-brown magmatic hornblende; plagioclase is zoned in both domains. Olivine (bearing) gabbros have 4-8 mm skeletal olivine pseudomorphs with roundish inclusions of chromite and plagioclase. Oxide (disseminated) gabbros comprise variable amounts of plagioclase, clinopyroxene, Oman paleo ridge.

  2. Afetividade, ensino e aprendizagem: um estudo no GT20 da ANPEd

    Directory of Open Access Journals (Sweden)

    Elvira Cristina Martins Tassoni

    Full Text Available Este artigo traz um levantamento bibliográfico dos trabalhos apresentados no GT20 - Psicologia da Educação da ANPEd (Associação Nacional de Pós-Graduação e Pesquisa em Educação no período de 2000 a 2010. O objetivo foi rastrear as produções científicas mais recentes que discutem a afetividade e sua relação com os processos de ensino e aprendizagem. Apresenta as perspectivas teóricas em que os estudos sobre a afetividade foram abordados e em que medida tais estudos discutem as influências entre os aspectos afetivos e os processos de ensino e aprendizagem. Os trabalhos foram selecionados segundo os procedimentos metodológicos da análise de conteúdo fundamentada em Bardin (1977. Os resultados permitiram a construção de um panorama a respeito dos estudos sobre afetividade, apontando tendências, períodos em que as discussões sobre o tema foram mais intensas e, sobretudo, demonstrando que tal temática vem marcando presença constante nas discussões das Reuniões Anuais da ANPEd.

  3. Free Moisture in GT-73 Resin Waste Generated from the Effluent Treatment Facility

    International Nuclear Information System (INIS)

    Kaplan, D.I.

    2002-01-01

    Solid Waste Division is presently evaluating whether to transfer spent resin generated from the Effluent Treatment Facility (ETF) to the Nevada Test Site (NTS). One of the criteria for the waste to be accepted at the NTS is that the waste must not contain more than 1 vol-percent free liquid. This criterion reduces the amount of liquid, a primary vector for subsurface contaminant migration (along with colloids), introduced into the repository. This criterion also serves to reduce the chance of an accidental spill during transport of the waste to the NTS. On December 15, 1997, a shipment from Fernald to the NTS leaked some liquid waste onto a highway in Kingman, Arizona, resulting in a Type B Accident Investigation. The direct cause of the leak was attributed to broken welds related to the use of substandard containers. The overall objective of this study was to provide guidance as to whether the spent GT-73 resin would meet the free moisture WAC set by the NTS

  4. Expression of transgenes targeted to the Gt(ROSA26Sor locus is orientation dependent.

    Directory of Open Access Journals (Sweden)

    Douglas Strathdee

    2006-12-01

    Full Text Available Targeting transgenes to a chosen location in the genome has a number of advantages. A single copy of the DNA construct can be inserted by targeting into regions of chromatin that allow the desired developmental and tissue-specific expression of the transgene.In order to develop a reliable system for reproducibly expressing transgenes it was decided to insert constructs at the Gt(ROSA26Sor locus. A cytomegalovirus (CMV promoter was used to drive expression of the Tetracycline (tet transcriptional activator, rtTA2(s-M2, and test the effectiveness of using the ROSA26 locus to allow transgene expression. The tet operator construct was inserted into one allele of ROSA26 and a tet responder construct controlling expression of EGFP was inserted into the other allele.Expression of the targeted transgenes was shown to be affected by both the presence of selectable marker cassettes and by the orientation of the transgenes with respect to the endogenous ROSA26 promoter. These results suggest that transcriptional interference from the endogenous gene promoter or from promoters in the selectable marker cassettes may be affecting transgene expression at the locus. Additionally we have been able to determine the optimal orientation for transgene expression at the ROSA26 locus.

  5. A quantitative comparison of corrective and perfective maintenance

    Science.gov (United States)

    Henry, Joel; Cain, James

    1994-01-01

    This paper presents a quantitative comparison of corrective and perfective software maintenance activities. The comparison utilizes basic data collected throughout the maintenance process. The data collected are extensive and allow the impact of both types of maintenance to be quantitatively evaluated and compared. Basic statistical techniques test relationships between and among process and product data. The results show interesting similarities and important differences in both process and product characteristics.

  6. The perfect family: decision making in biparental care.

    Science.gov (United States)

    Akçay, Erol; Roughgarden, Joan

    2009-10-13

    Previous theoretical work on parental decisions in biparental care has emphasized the role of the conflict between evolutionary interests of parents in these decisions. A prominent prediction from this work is that parents should compensate for decreases in each other's effort, but only partially so. However, experimental tests that manipulate parents and measure their responses fail to confirm this prediction. At the same time, the process of parental decision making has remained unexplored theoretically. We develop a model to address the discrepancy between experiments and the theoretical prediction, and explore how assuming different decision making processes changes the prediction from the theory. We assume that parents make decisions in behavioral time. They have a fixed time budget, and allocate it between two parental tasks: provisioning the offspring and defending the nest. The proximate determinant of the allocation decisions are parents' behavioral objectives. We assume both parents aim to maximize the offspring production from the nest. Experimental manipulations change the shape of the nest production function. We consider two different scenarios for how parents make decisions: one where parents communicate with each other and act together (the perfect family), and one where they do not communicate, and act independently (the almost perfect family). The perfect family model is able to generate all the types of responses seen in experimental studies. The kind of response predicted depends on the nest production function, i.e. how parents' allocations affect offspring production, and the type of experimental manipulation. In particular, we find that complementarity of parents' allocations promotes matching responses. In contrast, the relative responses do not depend on the type of manipulation in the almost perfect family model. These results highlight the importance of the interaction between nest production function and how parents make decisions

  7. Quality strategies implemented within the tourism agency Perfect Tour

    Directory of Open Access Journals (Sweden)

    Madar, A.

    2012-01-01

    Full Text Available The paper presents the quality strategies adopted by the tourism agency Perfect Tour. The most important advantages of the Romanian agency in comparison with its competitors are: the focus on high quality services, cooperation with other international agencies, entering new fields like medical tourism and sole representative of Disneyland Paris. The strategies adopted explain the good financial results even in the period of crisis.

  8. A psychogenic dystonia perfect responsive to antidepressant treatment.

    OpenAIRE

    Volkan Solmaz; Durdane Aksoy; Betul Cevik; Semiha Gulsum Kurt; Elmas Pekdas; Sema inanir

    2014-01-01

    After ruling out of organic causes, movement disorders are named as psychogenic movement disorders, it can mimic perfectly Organic movement disorders, but with a good history, clinical observations and detailed examination is very helpful in the diagnosis of this disease. In here we will present a 15 years old male patient, he was complaining of urinary incontinence at night, emerging dystonic posture especially in crowded environments, eating, and during activities that require attention, fo...

  9. Perfect independent sets with respect to infinitely many relations

    Czech Academy of Sciences Publication Activity Database

    Doležal, Martin; Kubiś, Wieslaw

    2016-01-01

    Roč. 55, č. 7 (2016), s. 847-856 ISSN 0933-5846 R&D Projects: GA ČR(CZ) GA14-07880S Institutional support: RVO:67985840 Keywords : perfect clique * free subgroup * open relation Subject RIV: BA - General Mathematics Impact factor: 0.394, year: 2016 http://link.springer.com/article/10.1007%2Fs00153-016-0498-3

  10. Comment on ``Perfect imaging with positive refraction in three dimensions''

    Science.gov (United States)

    Merlin, R.

    2010-11-01

    Leonhardt and Philbin [Phys. Rev. APLRAAN1050-294710.1103/PhysRevA.81.011804 81, 011804(R) (2010)] have recently constructed a mathematical proof that the Maxwell's fish-eye lens provides perfect imaging of electromagnetic waves without negative refraction. In this comment, we argue that the unlimited resolution is an artifact of having introduced an unphysical drain at the position of the geometrical image. The correct solution gives focusing consistent with the standard diffraction limit.

  11. Comment on ''Perfect imaging with positive refraction in three dimensions''

    International Nuclear Information System (INIS)

    Merlin, R.

    2010-01-01

    Leonhardt and Philbin [Phys. Rev. A 81, 011804(R) (2010)] have recently constructed a mathematical proof that the Maxwell's fish-eye lens provides perfect imaging of electromagnetic waves without negative refraction. In this comment, we argue that the unlimited resolution is an artifact of having introduced an unphysical drain at the position of the geometrical image. The correct solution gives focusing consistent with the standard diffraction limit.

  12. Hamiltonian formalism for perfect fluids in general relativity

    International Nuclear Information System (INIS)

    Demaret, J.; Moncrief, V.

    1980-01-01

    Schutz's Hamiltonian theory of a relativistic perfect fluid, based on the velocity-potential version of classical perfect fluid hydrodynamics as formulated by Seliger and Whitham, is used to derive, in the framework of the Arnowitt, Deser, and Misner (ADM) method, a general partially reduced Hamiltonian for relativistic systems filled with a perfect fluid. The time coordinate is chosen, as in Lund's treatment of collapsing balls of dust, as minus the only velocity potential different from zero in the case of an irrotational and isentropic fluid. A ''semi-Dirac'' method can be applied to quantize astrophysical and cosmological models in the framework of this partially reduced formalism. If one chooses Taub's adapted comoving coordinate system, it is possible to derive a fully reduced ADM Hamiltonian, which is equal to minus the total baryon number of the fluid, generalizing a result previously obtained by Moncrief in the more particular framework of Taub's variational principle, valid for self-gravitating barotropic relativistic perfect fluids. An unconstrained Hamiltonian density is then explicitly derived for a fluid obeying the equation of state p=(gamma-1)rho (1 < or = γ < or = 2), which can adequately describe the phases of very high density attained in a catastrophic collapse or during the early stages of the Universe. This Hamiltonian density, shown to be equivalent to Moncrief's in the particular case of an isentropic fluid, can be simplified for fluid-filled class-A diagonal Bianchi-type cosmological models and appears as a suitable starting point for the study of the canonical quantization of these models

  13. Overlapped illusion optics: a perfect lens brings a brighter feature

    Energy Technology Data Exchange (ETDEWEB)

    Xu Yadong; Gao Lei; Chen Huanyang [School of Physical Science and Technology, Soochow University, Suzhou, Jiangsu 215006 (China); Du Shengwang, E-mail: kenyon@ust.hk [Department of Physics, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon (Hong Kong)

    2011-02-15

    In this paper, we show that a perfect lens can be employed to make multiple objects appear like only one object in the far field, leading to a new concept in illusion optics. Numerical simulations have been performed to verify the functionalities for both passive and active objects. The conceptual device can be utilized to enhance the illumination brightness for both incoherent and coherent systems.

  14. Overlapped illusion optics: a perfect lens brings a brighter feature

    International Nuclear Information System (INIS)

    Xu Yadong; Gao Lei; Chen Huanyang; Du Shengwang

    2011-01-01

    In this paper, we show that a perfect lens can be employed to make multiple objects appear like only one object in the far field, leading to a new concept in illusion optics. Numerical simulations have been performed to verify the functionalities for both passive and active objects. The conceptual device can be utilized to enhance the illumination brightness for both incoherent and coherent systems.

  15. The perfect family: decision making in biparental care.

    Directory of Open Access Journals (Sweden)

    Erol Akçay

    Full Text Available Previous theoretical work on parental decisions in biparental care has emphasized the role of the conflict between evolutionary interests of parents in these decisions. A prominent prediction from this work is that parents should compensate for decreases in each other's effort, but only partially so. However, experimental tests that manipulate parents and measure their responses fail to confirm this prediction. At the same time, the process of parental decision making has remained unexplored theoretically. We develop a model to address the discrepancy between experiments and the theoretical prediction, and explore how assuming different decision making processes changes the prediction from the theory.We assume that parents make decisions in behavioral time. They have a fixed time budget, and allocate it between two parental tasks: provisioning the offspring and defending the nest. The proximate determinant of the allocation decisions are parents' behavioral objectives. We assume both parents aim to maximize the offspring production from the nest. Experimental manipulations change the shape of the nest production function. We consider two different scenarios for how parents make decisions: one where parents communicate with each other and act together (the perfect family, and one where they do not communicate, and act independently (the almost perfect family.The perfect family model is able to generate all the types of responses seen in experimental studies. The kind of response predicted depends on the nest production function, i.e. how parents' allocations affect offspring production, and the type of experimental manipulation. In particular, we find that complementarity of parents' allocations promotes matching responses. In contrast, the relative responses do not depend on the type of manipulation in the almost perfect family model. These results highlight the importance of the interaction between nest production function and how parents make

  16. A not-so-short description of the PERFECT platform

    International Nuclear Information System (INIS)

    Bugat, S.; Zeghadi, A.; Adjanor, G.

    2010-01-01

    This article describes the building of the so-called 'PERFECT platform', which main issue was to allow the development of the PERFECT end-products dedicated to the prediction of the degradation of material properties due to irradiation. First, the general principles used to build the platform are detailed. Such principles guided the choices of preferential development language, architecture, and operating system. The architecture of the platform is then described. It allows an easy development of the end-products, and a 'black-box' integration of the codes developed during the project. Each end-product can be seen as a sequence of modules, each module representing a physical phenomenon in time and space. The platform is very flexible, so that different methodologies can be tested and compared inside an end-product. The second part is devoted to the description of a classical PERFECT study, defined thanks to the graphical user interface developed in the project. Focus is made in particular on how a selection of modules is done, how the input data can be entered, and how the study execution is fully controlled by the user. A final description of the post-processing facilities on the results is exposed.

  17. Repeated causal decision making.

    Science.gov (United States)

    Hagmayer, York; Meder, Björn

    2013-01-01

    Many of our decisions refer to actions that have a causal impact on the external environment. Such actions may not only allow for the mere learning of expected values or utilities but also for acquiring knowledge about the causal structure of our world. We used a repeated decision-making paradigm to examine what kind of knowledge people acquire in such situations and how they use their knowledge to adapt to changes in the decision context. Our studies show that decision makers' behavior is strongly contingent on their causal beliefs and that people exploit their causal knowledge to assess the consequences of changes in the decision problem. A high consistency between hypotheses about causal structure, causally expected values, and actual choices was observed. The experiments show that (a) existing causal hypotheses guide the interpretation of decision feedback, (b) consequences of decisions are used to revise existing causal beliefs, and (c) decision makers use the experienced feedback to induce a causal model of the choice situation even when they have no initial causal hypotheses, which (d) enables them to adapt their choices to changes of the decision problem. (PsycINFO Database Record (c) 2013 APA, all rights reserved).

  18. The gas turbine-modular helium reactor (GT-MHR), high efficiency, cost competitive, nuclear energy for the next century

    International Nuclear Information System (INIS)

    Zgliczynski, J.B.; Silady, F.A.; Neylan, A.J.

    1994-04-01

    The Gas Turbine-Modular Helium Reactor (GT-MHR) is the result of coupling the evolution of a small passively safe reactor with key technology developments in the US during the last decade: large industrial gas turbines, large active magnetic bearings, and compact, highly effective plate-fin heat exchangers. The GT-MHR is the only reactor concept which provides a step increase in economic performance combined with increased safety. This is accomplished through its unique utilization of the Brayton cycle to produce electricity directly with the high temperature helium primary coolant from the reactor directly driving the gas turbine electrical generator. This cannot be accomplished with another reactor concept. It retains the high levels of passive safety and the standardized modular design of the steam cycle MHTGR, while showing promise for a significant reduction in power generating costs by increasing plant net efficiency to a remarkable 47%

  19. GT-MHR COMMERCIALIZATION STUDY TECHNICAL PROGRESS AND COST MANAGEMENT REPORT FOR THE PERIOD AUGUST 1 THROUGH AUGUST 31, 2003

    International Nuclear Information System (INIS)

    Shenoy, A.S.

    2003-01-01

    OAK A271 GT-MHR COMERCIALiZATION STUDY TECHNICAL PROGRESS AND COST MANAGEMENT REPORT FOR THE PERIOD AUGUST 1 THROUGH AUGUST 31, 2003. In the process of fabricating the MHR-1 irradiation test capsule, Petten has advised that three thermocouples (out of 24) and the Self Powered Neutron detector were damaged during high temperature brazing with the upper capsule lid. Procurement of new TCs and SPN is in process but there will be a delay in the irradiation test of about nine weeks. Startup of the irradiation is now projected to be July or August 2004. In preparation for performing the nuclear design analysis activities required by the advanced fuel studies task, a complete 3-D nuclear design analysis is first being performed of the GT-MHR reference design. This will serve as the baseline for studies of the advanced fuel nuclear design performance

  20. GT-MHR as economical highly efficient inherently safe modular gas cooled reactor for electric power generation

    International Nuclear Information System (INIS)

    Baydakov, A.G.; Kodochigov, N.G.; Kuzavkov, N.G.; Vorontsov, V.E.

    2001-01-01

    The Gas Turbine Modular Helium Reactor (GT-MHR) project is a joint effort of organisations in the Russian Federation co-ordinated by the Ministry on Atomic Energy (MINATOM), General Atomics in the United States, Framatome in France, and Fuji Electric in Japan. This paper describes the structure, objectives and history of the GT-MHR project, as well as the plant design, including plant layout, components and fuel. It summarises the results of evaluations of the design safety characteristics and economics, for both a plutonium fueled single module and a uranium fueled four module plant. The plans and anticipated structure for an international project to construct the plant are also summarised. (author)

  1. [Effects of nitriles and amides on the growth and the nitrile hydratase activity of the Rhodococcus sp. strain gt1].

    Science.gov (United States)

    Maksimov, A Iu; Kuznetsova, M V; Ovechkina, G V; Kozlov, S V; Maksimova, Iu G; Demakov, V A

    2003-01-01

    Effects of some nitriles and amides, as well as glucose and ammonium, on the growth and the nitrile hydratase (EC 4.2.1.84) activity of the Rhodococcus sp. strain gt1 isolated from soil were studied. The activity of nitrile hydratase mainly depended on carbon and nitrogen supply to cells. The activity of nitrile hydratase was high in the presence of glucose and ammonium at medium concentrations and decreased at concentrations of glucose more than 0.3%. Saturated unsubstituted aliphatic nitriles and amides were found to be a good source of nitrogen and carbon. However, the presence of nitriles and amides in the medium was not absolutely necessary for the expression of the activity of nitrile hydratase isolated from the Rhodococcus sp. strain gt1.

  2. Effects of Huang Bai (Phellodendri Cortex and Three Other Herbs on GnRH and GH Levels in GT1–7 and GH3 Cells

    Directory of Open Access Journals (Sweden)

    Sun Haeng Lee

    2016-01-01

    Full Text Available The present study was to evaluate the effects of Huang Bai, Zhi Mu, Mai Ya, and Xia Ku Cao on hormone using the GT1–7 and GH3 cells. The GT1–7 and GH3 cell lines were incubated with DW; DMSO; and 30, 100, or 300 μg/mL of one of the four extract solutions in serum-free media for 24 hours. The MTT assay was performed to determine the cytotoxicity of the four herbs. The GT1–7 and GH3 cells were incubated in DW, estradiol (GT1–7 only, or noncytotoxic herb solutions in serum-free medium for 24 hours. A quantitative RT-PCR and western blot were performed to measure the GnRH expression in GT1–7 cells and GH expression in GH3 cells. Huang Bai, Zhi Mu, Xia Ku Cao, and Mai Ya inhibited the GnRH mRNA expression in GT1–7 cells, whereas Huang Bai enhanced GH mRNA expression in GH3 cells. Additionally, Xia Ku Cao inhibited GnRH protein expression in GT1–7 cells and Huang Bai promoted GH protein expression in GH3 cells. The findings suggest that Huang Bai can delay puberty by inhibiting GnRH synthesis in the hypothalamus while also accelerating growth by promoting GH synthesis and secretion in the pituitary.

  3. Expansion of protein domain repeats.

    Directory of Open Access Journals (Sweden)

    Asa K Björklund

    2006-08-01

    Full Text Available Many proteins, especially in eukaryotes, contain tandem repeats of several domains from the same family. These repeats have a variety of binding properties and are involved in protein-protein interactions as well as binding to other ligands such as DNA and RNA. The rapid expansion of protein domain repeats is assumed to have evolved through internal tandem duplications. However, the exact mechanisms behind these tandem duplications are not well-understood. Here, we have studied the evolution, function, protein structure, gene structure, and phylogenetic distribution of domain repeats. For this purpose we have assigned Pfam-A domain families to 24 proteomes with more sensitive domain assignments in the repeat regions. These assignments confirmed previous findings that eukaryotes, and in particular vertebrates, contain a much higher fraction of proteins with repeats compared with prokaryotes. The internal sequence similarity in each protein revealed that the domain repeats are often expanded through duplications of several domains at a time, while the duplication of one domain is less common. Many of the repeats appear to have been duplicated in the middle of the repeat region. This is in strong contrast to the evolution of other proteins that mainly works through additions of single domains at either terminus. Further, we found that some domain families show distinct duplication patterns, e.g., nebulin domains have mainly been expanded with a unit of seven domains at a time, while duplications of other domain families involve varying numbers of domains. Finally, no common mechanism for the expansion of all repeats could be detected. We found that the duplication patterns show no dependence on the size of the domains. Further, repeat expansion in some families can possibly be explained by shuffling of exons. However, exon shuffling could not have created all repeats.

  4. Thermo-economic comparative analysis of gas turbine GT10 integrated with air and steam bottoming cycle

    Science.gov (United States)

    Czaja, Daniel; Chmielnak, Tadeusz; Lepszy, Sebastian

    2014-12-01

    A thermodynamic and economic analysis of a GT10 gas turbine integrated with the air bottoming cycle is presented. The results are compared to commercially available combined cycle power plants based on the same gas turbine. The systems under analysis have a better chance of competing with steam bottoming cycle configurations in a small range of the power output capacity. The aim of the calculations is to determine the final cost of electricity generated by the gas turbine air bottoming cycle based on a 25 MW GT10 gas turbine with the exhaust gas mass flow rate of about 80 kg/s. The article shows the results of thermodynamic optimization of the selection of the technological structure of gas turbine air bottoming cycle and of a comparative economic analysis. Quantities are determined that have a decisive impact on the considered units profitability and competitiveness compared to the popular technology based on the steam bottoming cycle. The ultimate quantity that can be compared in the calculations is the cost of 1 MWh of electricity. It should be noted that the systems analyzed herein are power plants where electricity is the only generated product. The performed calculations do not take account of any other (potential) revenues from the sale of energy origin certificates. Keywords: Gas turbine air bottoming cycle, Air bottoming cycle, Gas turbine, GT10

  5. Putative DNA-dependent RNA polymerase in Mitochondrial Plasmid of Paramecium caudatum Stock GT704

    Directory of Open Access Journals (Sweden)

    Trina Ekawati Tallei

    2015-10-01

    Full Text Available Mitochondria of Paramecium caudatum stock GT704 has a set of four kinds of linear plasmids with sizes of 8.2, 4.1, 2.8 and 1.4 kb. The plasmids of 8.2 and 2.8 kb exist as dimers consisting of 4.1- and 1.4-kb monomers, respectively. The plasmid 2.8 kb, designated as pGT704-2.8, contains an open reading frame encodes for putative DNA-dependent RNA polymerase (RNAP. This study reveals that this RNAP belongs to superfamily of DNA/RNA polymerase and family of T7/T3 single chain RNA polymerase and those of mitochondrial plasmid of fungi belonging to Basidiomycota and Ascomycota. It is suggested that RNAP of pGT704-2.8 can perform transcription without transcription factor as promoter recognition. Given that only two motifs were found, it could not be ascertained whether this RNAP has a full function independently or integrated with mtDNA in carrying out its function.

  6. Intermonitor reliability of the GT3X+ accelerometer at hip, wrist and ankle sites during activities of daily living

    International Nuclear Information System (INIS)

    Ozemek, Cemal; Wilkerson, Brittany S; Kaminsky, Leonard A; Kirschner, Monica M; Byun, Wonwoo

    2014-01-01

    The triaxial GT3X+ accelerometer can measure activity counts in the vertical, horizontal right to left, horizontal front to back planes, and can generate a summative score of the three axes represented by vector magnitude (VM). Information on the reliability of the GT3X+ at the hip, wrist and ankle sites, over all axes and VM during activities of daily living (ADL) is lacking in the literature. Forty healthy adults (14 men and 26 women) were randomly assigned to perform 10 of 20 ADL (consisting of sedentary, housework, yard work, locomotive and recreational activities) while wearing two monitors on the hip, wrist and ankle. Subjects performed each ADL over 7 min and the mean activity counts during the last 4 min were used for analyses. Average intraclass correlations between monitors were high for the three sites for each axis and VM (hip: 0.943, 0.857, 0.864 and 0.966, respectively; wrist: 0.994, 0.963, 0.961 and 0.989, respectively; ankle: 0.977, 0.979, 0.927 and 0.986, respectively). These data suggest that GT3X+ accelerometers measurements made from the hip, wrist and ankle sites are reliable during ADL across all axes and VM. (paper)

  7. 10 CFR 609.16 - Perfection of liens and preservation of collateral.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Perfection of liens and preservation of collateral. 609.16... THAT EMPLOY INNOVATIVE TECHNOLOGIES § 609.16 Perfection of liens and preservation of collateral. (a... to perfect and maintain liens, as applicable, on assets which are pledged as collateral for the...

  8. An Infinite Family of Circulant Graphs with Perfect State Transfer in Discrete Quantum Walks

    OpenAIRE

    Zhan, Hanmeng

    2017-01-01

    We study perfect state transfer in a discrete quantum walk. In particular, we show that there are infinitely many $4$-regular circulant graphs that admit perfect state transfer between antipodal vertices. To the best of our knowledge, previously there was no infinite family of $k$-regular graphs with perfect state transfer, for any $k\\ge 3$.

  9. Approximating perfection a mathematician's journey into the world of mechanics

    CERN Document Server

    Lebedev, Leonid P

    2004-01-01

    This is a book for those who enjoy thinking about how and why Nature can be described using mathematical tools. Approximating Perfection considers the background behind mechanics as well as the mathematical ideas that play key roles in mechanical applications. Concentrating on the models of applied mechanics, the book engages the reader in the types of nuts-and-bolts considerations that are normally avoided in formal engineering courses: how and why models remain imperfect, and the factors that motivated their development. The opening chapter reviews and reconsiders the basics of c

  10. Extinction in finite perfect crystals: Case of a sphere

    International Nuclear Information System (INIS)

    Al Haddad, M.; Becker, P.

    1990-01-01

    The extinction factor in finite perfect crystals is calculated from pure dynamical theory. In particular, a detailed solution is proposed for a sphere, in which case the extinction factor depends on the Bragg angle θ and the parameter (R/Λ), where R is the radius of the crystal and Λ the extinction length. An approximate solution based on the Laue geometry is proposed and corrections to take care of the complex boundary conditions are presented. An expression easily usable in refinement programs is proposed that fits the exact value to better than 1%. (orig.)

  11. Seeking perfection: a Kantian look at human genetic engineering.

    Science.gov (United States)

    Gunderson, Martin

    2007-01-01

    It is tempting to argue that Kantian moral philosophy justifies prohibiting both human germ-line genetic engineering and non-therapeutic genetic engineering because they fail to respect human dignity. There are, however, good reasons for resisting this temptation. In fact, Kant's moral philosophy provides reasons that support genetic engineering-even germ-line and non-therapeutic. This is true of Kant's imperfect duties to seek one's own perfection and the happiness of others. It is also true of the categorical imperative. Kant's moral philosophy does, however, provide limits to justifiable genetic engineering.

  12. Using a quantum dot system to realize perfect state transfer

    International Nuclear Information System (INIS)

    Li Ji; Wu Shi-Hai; Zhang Wen-Wen; Xi Xiao-Qiang

    2011-01-01

    There are some disadvantages to Nikolopoulos et al.'s protocol [Nikolopoulos G M, Petrosyan D and Lambropoulos P 2004 Europhys. Lett. 65 297] where a quantum dot system is used to realize quantum communication. To overcome these disadvantages, we propose a protocol that uses a quantum dot array to construct a four-qubit spin chain to realize perfect quantum state transfer (PQST). First, we calculate the interaction relation for PQST in the spin chain. Second, we review the interaction between the quantum dots in the Heitler—London approach. Third, we present a detailed program for designing the proper parameters of a quantum dot array to realize PQST. (general)

  13. Non-adiabatic perturbations in multi-component perfect fluids

    Energy Technology Data Exchange (ETDEWEB)

    Koshelev, N.A., E-mail: koshna71@inbox.ru [Ulyanovsk State University, Leo Tolstoy str 42, 432970 (Russian Federation)

    2011-04-01

    The evolution of non-adiabatic perturbations in models with multiple coupled perfect fluids with non-adiabatic sound speed is considered. Instead of splitting the entropy perturbation into relative and intrinsic parts, we introduce a set of symmetric quantities, which also govern the non-adiabatic pressure perturbation in models with energy transfer. We write the gauge invariant equations for the variables that determine on a large scale the non-adiabatic pressure perturbation and the rate of changes of the comoving curvature perturbation. The analysis of evolution of the non-adiabatic pressure perturbation has been made for several particular models.

  14. Non-adiabatic perturbations in multi-component perfect fluids

    International Nuclear Information System (INIS)

    Koshelev, N.A.

    2011-01-01

    The evolution of non-adiabatic perturbations in models with multiple coupled perfect fluids with non-adiabatic sound speed is considered. Instead of splitting the entropy perturbation into relative and intrinsic parts, we introduce a set of symmetric quantities, which also govern the non-adiabatic pressure perturbation in models with energy transfer. We write the gauge invariant equations for the variables that determine on a large scale the non-adiabatic pressure perturbation and the rate of changes of the comoving curvature perturbation. The analysis of evolution of the non-adiabatic pressure perturbation has been made for several particular models

  15. Analysis of the Perfect Table Fuzzy Rainbow Tradeoff

    Directory of Open Access Journals (Sweden)

    Byoung-Il Kim

    2014-01-01

    Full Text Available Cryptanalytic time memory tradeoff algorithms are tools for inverting one-way functions, and they are used in practice to recover passwords that restrict access to digital documents. This work provides an accurate complexity analysis of the perfect table fuzzy rainbow tradeoff algorithm. Based on the analysis results, we show that the lesser known fuzzy rainbow tradeoff performs better than the original rainbow tradeoff, which is widely believed to be the best tradeoff algorithm. The fuzzy rainbow tradeoff can attain higher online efficiency than the rainbow tradeoff and do so at a lower precomputation cost.

  16. Assessing Measures of Order Flow Toxicity via Perfect Trade Classification

    DEFF Research Database (Denmark)

    Andersen, Torben G.; Bondarenko, Oleg

    . The VPIN metric involves decomposing volume into active buys and sells. We use the best-bid-offer (BBO) files from the CME Group to construct (near) perfect trade classification measures for the E-mini S&P 500 futures contract. We investigate the accuracy of the ELO Bulk Volume Classification (BVC) scheme...... systematic classification errors that are correlated with trading volume and return volatility. When controlling for trading intensity and volatility, the BVC-VPIN measure has no incremental predictive power for future volatility. We conclude that VPIN is not suitable for measuring order flow imbalances....

  17. Artificial hairy surfaces with a nearly perfect hydrophobic response.

    Science.gov (United States)

    Hsu, Shu-Hau; Sigmund, Wolfgang M

    2010-02-02

    A nearly perfect hydrophobic interface by dint of mimicking hairs of arthropods was achieved for the first time. These Gamma-shape artificial hairs were made via a membrane casting technique on polypropylene substrates. This extreme hydrophobicity merely arises from microstructure modification, and no further chemical treatments are needed. The ultralow adhesion to water droplets was evaluated through video assessment, and it is believed to be attributed to the mechanical response of the artificial hairs. The principle of this fabrication technique is accessible and is expected to be compatible with large-area fabrication of superhydrophobic interfaces.

  18. The Hamiltonian structure of general relativistic perfect fluids

    International Nuclear Information System (INIS)

    Bao, D.; Houston Univ., TX; Marsden, J.; Walton, R.

    1985-01-01

    We show that the evolution equations for a perfect fluid coupled to general relativity in a general lapse and shift, are Hamiltonian relative to a certain Poisson structure. For the fluid variables, a Lie-Poisson structure associated to the dual of a semi-direct product Lie algebra is used, while the bracket for the gravitational variables has the usual canonical symplectic structure. The evolution is governed by a Hamiltonian which is equivalent to that obtained from a canonical analysis. The relationship of our Hamiltonian structure with other approaches in the literature, such as Clebsch potentials, Lagrangian to Eulerian transformations, and its use in clarifying linearization stability, are discussed. (orig.)

  19. Manipulating the loss in electromagnetic cloaks for perfect wave absorption.

    Science.gov (United States)

    Argyropoulos, Christos; Kallos, Efthymios; Zhao, Yan; Hao, Yang

    2009-05-11

    We examine several ways to manipulate the loss in electro-magnetic cloaks, based on transformation electromagnetics. It is found that, by utilizing inherent electric and magnetic losses of metamaterials, perfect wave absorption can be achieved based on several popular designs of electromagnetic cloaks. A practical implementation of the absorber, consisting of ten discrete layers of metamaterials, is proposed. The new devices demonstrate super-absorptivity over a moderate wideband range, suitable for both microwave and optical applications. It is corroborated that the device is functional with a subwavelength thickness and, hence, advantageous compared to the conventional absorbers.

  20. TPH2 -703G/T SNP may have important effect on susceptibility to suicidal behavior in major depression.

    Science.gov (United States)

    Yoon, Ho-Kyoung; Kim, Yong-Ku

    2009-04-30

    Serotonergic system-related genes can be good candidate genes for both major depressive disorder (MDD) and suicidal behavior. In this study, we aimed to investigate the association of serotonin 2A receptor gene -1438A/G SNP (HTR2A -1438A/G), tryptophan hydroxylase 2 gene -703G/T SNP (TPH2 -703G/T) and serotonin 1A receptor C-1019G (HTR1A C-1019G) with suicidal behavior. One hundred and eighty one suicidal depressed patients and 143 non-suicidal depressed patients who met DSM-IV criteria for major depressive disorder were recruited from patients who were admitted to Korea University Ansan Hospital. One hundred seventy six normal controls were healthy volunteers who were recruited by local advertisement. Patients and normal controls were genotyped for HTR2A -1438A/G, TPH2 -703G/T and 5-HT1A C-1019G. The suicidal depressed patients were evaluated by the lethality of individual suicide attempts using Weisman and Worden's risk-rescue rating (RRR) and the Lethality Suicide Attempt Rating Scale-updated (LSARS-II). In order to assess the severity of depressive symptoms of patients, Hamilton's Depression Rating Scale (HDRS) was administered. Genotype and allele frequencies were compared between groups by chi(2) statistics. Association of genotype of the candidate genes with the lethality of suicidal behavior was examined with ANOVA by comparing the mean scores of LSARS and RRR according to the genotype. There were statistically significant differences in the genotype distributions and allele frequencies of TPH2 -703G/T between the suicidal depressive group and the normal control group. The homozygous allele G (G/G genotype) frequency was significantly higher in suicidal depressed patients than in controls. However, no differences in either genotype distribution or in allele frequencies of HTR2A -1438A/G and HTR1A C-1019G were observed between the suicidal depressed patients, the non-suicidal depressed patients, and the normal controls. There were no differences in the

  1. Coordinate transformations make perfect invisibility cloaks with arbitrary shape

    International Nuclear Information System (INIS)

    Yan Wei; Yan Min; Ruan Zhichao; Qiu Min

    2008-01-01

    By investigating wave properties at cloak boundaries, invisibility cloaks with arbitrary shape constructed by general coordinate transformations are confirmed to be perfectly invisible to the external incident wave. The differences between line transformed cloaks and point transformed cloaks are discussed. The fields in the cloak medium are found analytically to be related to the fields in the original space via coordinate transformation functions. At the exterior boundary of the cloak, it is shown that no reflection is excited even though the permittivity and permeability do not always have a perfectly matched layer form, whereas at the inner boundary, no reflection is excited either, and in particular no field can penetrate into the cloaked region. However, for the inner boundary of any line transformed cloak, the permittivity and permeability in a specific tangential direction are always required to be infinitely large. Furthermore, the field discontinuity at the inner boundary always exists; the surface current is induced to make this discontinuity self-consistent. A point transformed cloak does not experience such problems. The tangential fields at the inner boundary are all zero, implying that no field discontinuity exists

  2. Spherically symmetric Einstein-aether perfect fluid models

    Energy Technology Data Exchange (ETDEWEB)

    Coley, Alan A.; Latta, Joey [Department of Mathematics and Statistics, Dalhousie University, Halifax, Nova Scotia, B3H 3J5 (Canada); Leon, Genly [Instituto de Física, Pontificia Universidad Católica de Valparaíso, Casilla 4950, Valparaíso (Chile); Sandin, Patrik, E-mail: aac@mathstat.dal.ca, E-mail: genly.leon@ucv.cl, E-mail: patrik.sandin@aei.mpg.de, E-mail: lattaj@mathstat.dal.ca [Max-Planck-Institut für Gravitationsphysik (Albert-Einstein-Institut), Am Mühlenberg 1, D-14476 Potsdam (Germany)

    2015-12-01

    We investigate spherically symmetric cosmological models in Einstein-aether theory with a tilted (non-comoving) perfect fluid source. We use a 1+3 frame formalism and adopt the comoving aether gauge to derive the evolution equations, which form a well-posed system of first order partial differential equations in two variables. We then introduce normalized variables. The formalism is particularly well-suited for numerical computations and the study of the qualitative properties of the models, which are also solutions of Horava gravity. We study the local stability of the equilibrium points of the resulting dynamical system corresponding to physically realistic inhomogeneous cosmological models and astrophysical objects with values for the parameters which are consistent with current constraints. In particular, we consider dust models in (β−) normalized variables and derive a reduced (closed) evolution system and we obtain the general evolution equations for the spatially homogeneous Kantowski-Sachs models using appropriate bounded normalized variables. We then analyse these models, with special emphasis on the future asymptotic behaviour for different values of the parameters. Finally, we investigate static models for a mixture of a (necessarily non-tilted) perfect fluid with a barotropic equations of state and a scalar field.

  3. A perfectly conducting surface in electrodynamics with Lorentz symmetry breaking

    Science.gov (United States)

    Borges, L. H. C.; Barone, F. A.

    2017-10-01

    In this paper we consider a model which exhibits explicit Lorentz symmetry breaking due to the presence of a single background vector v^{μ } coupled to the gauge field. We investigate such a theory in the vicinity of a perfectly conducting plate for different configurations of v^{μ }. First we consider no restrictions on the components of the background vector and we treat it perturbatively up to second order. Next, we treat v^{μ } exactly for two special cases: the first one is when it has only components parallel to the plate, and the second one when it has a single component perpendicular to the plate. For all these configurations, the propagator for the gauge field and the interaction force between the plate and a point-like electric charge are computed. Surprisingly, it is shown that the image method is valid in our model and we argue that it is a non-trivial result. We show there arises a torque on the mirror with respect to its positioning in the background field when it interacts with a point-like charge. It is a new effect with no counterpart in theories with Lorentz symmetry in the presence of a perfect mirror.

  4. A perfectly conducting surface in electrodynamics with Lorentz symmetry breaking

    Energy Technology Data Exchange (ETDEWEB)

    Borges, L.H.C. [UNESP, Campus de Guaratingueta, DFQ, Guaratingueta, SP (Brazil); Barone, F.A. [IFQ, Universidade Federal de Itajuba, Itajuba, MG (Brazil)

    2017-10-15

    In this paper we consider a model which exhibits explicit Lorentz symmetry breaking due to the presence of a single background vector v{sup μ} coupled to the gauge field. We investigate such a theory in the vicinity of a perfectly conducting plate for different configurations of v{sup μ}. First we consider no restrictions on the components of the background vector and we treat it perturbatively up to second order. Next, we treat v{sup μ} exactly for two special cases: the first one is when it has only components parallel to the plate, and the second one when it has a single component perpendicular to the plate. For all these configurations, the propagator for the gauge field and the interaction force between the plate and a point-like electric charge are computed. Surprisingly, it is shown that the image method is valid in our model and we argue that it is a non-trivial result. We show there arises a torque on the mirror with respect to its positioning in the background field when it interacts with a point-like charge. It is a new effect with no counterpart in theories with Lorentz symmetry in the presence of a perfect mirror. (orig.)

  5. Film repeats in radiology department

    International Nuclear Information System (INIS)

    Suwan, A. Z.; Al-Shakharah, A. I

    1997-01-01

    During a one year period, 4910 radiographs of 55780 films were repeated. The objective of our study was to analyse and to classify the causes in order to minimize the repeats, cut the expenses and to provide optimal radiographs for accurate diagnosis. Analysis of the different factors revealed that, 43.6% of film repeats in our service were due to faults in exposure factors, centering comprises 15.9% of the repeats, while too much collimation was responsible for 7.6% of these repeats. All of which can be decreased by awareness and programmed training of technicians. Film blurring caused by patient motion was also responsible for 4.9% for radiographs reexamination, which can be minimized by detailed explanation to the patient and providing the necessary privacy. Fogging of X-Ray films by improper storage or inadequate handling or processing faults were responsible for 14.5% in repeats in our study. Methods and criteria for proper storage and handling of films were discussed. Recommendation for using modern day-light and laser processor has been high lighted. Artefacts are noticeably high in our cases, due to spinal dresses and frequent usage of precious metals for c osmotic purposes in this part of the world. The repeated films comprise 8.8% of all films We conclude that, the main factor responsible for repeats of up to 81.6% of cases was the technologists, thus emphasizing the importance of adequate training of the technologists. (authors). 15 refs., 9 figs., 1 table

  6. Nifty Nines and Repeating Decimals

    Science.gov (United States)

    Brown, Scott A.

    2016-01-01

    The traditional technique for converting repeating decimals to common fractions can be found in nearly every algebra textbook that has been published, as well as in many precalculus texts. However, students generally encounter repeating decimal numerals earlier than high school when they study rational numbers in prealgebra classes. Therefore, how…

  7. Repeated Prescribed Burning in Aspen

    Science.gov (United States)

    Donald A. Perala

    1974-01-01

    Infrequent burning weather, low flammability of the aspen-hardwood association, and prolific sprouting and seeding of shrubs and hardwoods made repeated dormant season burning a poor tool to convert good site aspen to conifers. Repeat fall burns for wildlife habitat maintenance is workable if species composition changes are not important.

  8. Tevatron serial data repeater system

    International Nuclear Information System (INIS)

    Ducar, R.J.

    1981-01-01

    A ten megabit per second serial data repeater system has been developed for the 6.28km Tevatron accelerator. The repeaters are positioned at each of the thirty service buildings and accommodate control and abort system communications as well as distribution of the Tevatron time and energy clocks. The repeaters are transparent to the particular protocol of the transmissions. Serial data are encoded locally as unipolar two volt signals employing the self-clocking Manchester Bi-Phase code. The repeaters modulate the local signals to low-power bursts of 50 MHz rf carrier for the 260m transmission between service buildings. The repeaters also demodulate the transmission and restructure the data for local utilization. The employment of frequency discrimination techniques yields high immunity to the characteristic noise spectrum

  9. All-photonic quantum repeaters

    Science.gov (United States)

    Azuma, Koji; Tamaki, Kiyoshi; Lo, Hoi-Kwong

    2015-01-01

    Quantum communication holds promise for unconditionally secure transmission of secret messages and faithful transfer of unknown quantum states. Photons appear to be the medium of choice for quantum communication. Owing to photon losses, robust quantum communication over long lossy channels requires quantum repeaters. It is widely believed that a necessary and highly demanding requirement for quantum repeaters is the existence of matter quantum memories. Here we show that such a requirement is, in fact, unnecessary by introducing the concept of all-photonic quantum repeaters based on flying qubits. In particular, we present a protocol based on photonic cluster-state machine guns and a loss-tolerant measurement equipped with local high-speed active feedforwards. We show that, with such all-photonic quantum repeaters, the communication efficiency scales polynomially with the channel distance. Our result paves a new route towards quantum repeaters with efficient single-photon sources rather than matter quantum memories. PMID:25873153

  10. Repeatability of visual acuity measurement.

    Science.gov (United States)

    Raasch, T W; Bailey, I L; Bullimore, M A

    1998-05-01

    This study investigates features of visual acuity chart design and acuity testing scoring methods which affect the validity and repeatability of visual acuity measurements. Visual acuity was measured using the Sloan and British Standard letter series, and Landolt rings. Identifiability of the different letters as a function of size was estimated, and expressed in the form of frequency-of-seeing curves. These functions were then used to simulate acuity measurements with a variety of chart designs and scoring criteria. Systematic relationships exist between chart design parameters and acuity score, and acuity score repeatability. In particular, an important feature of a chart, that largely determines the repeatability of visual acuity measurement, is the amount of size change attributed to each letter. The methods used to score visual acuity performance also affect repeatability. It is possible to evaluate acuity score validity and repeatability using the statistical principles discussed here.

  11. Repeat polymorphisms in the Homo sapiens heme oxygenase-1 gene in diabetic and idiopathic gastroparesis

    Science.gov (United States)

    Gibbons, Simon J.; Grover, Madhusudan; Choi, Kyoung Moo; Wadhwa, Akhilesh; Zubair, Adeel; Wilson, Laura A.; Wu, Yanhong; Abell, Thomas L.; Hasler, William L.; Koch, Kenneth L.; McCallum, Richard W.; Nguyen, Linda A. B.; Parkman, Henry P.; Sarosiek, Irene; Snape, William J.; Tonascia, James; Hamilton, Frank A.; Pasricha, Pankaj J.

    2017-01-01

    Background Idiopathic and diabetic gastroparesis in Homo sapiens cause significant morbidity. Etiology or risk factors have not been clearly identified. Failure to sustain elevated heme oxygenase-1 (HO1) expression is associated with delayed gastric emptying in diabetic mice and polymorphisms in the HO1 gene (HMOX1, NCBI Gene ID:3162) are associated with worse outcomes in other diseases. Aim Our hypothesis was that longer polyGT alleles are more common in the HMOX1 genes of individuals with gastroparesis than in controls without upper gastrointestinal motility disorders. Methods Repeat length was determined in genomic DNA. Controls with diabetes (84 type 1, 84 type 2) and without diabetes (n = 170) were compared to diabetic gastroparetics (99 type 1, 72 type 2) and idiopathic gastroparetics (n = 234). Correlations of repeat lengths with clinical symptom sub-scores on the gastroparesis cardinal symptom index (GCSI) were done. Statistical analyses of short (32) repeat alleles and differences in allele length were used to test for associations with gastroparesis. Results The distribution of allele lengths was different between groups (P = 0.016). Allele lengths were longest in type 2 diabetics with gastroparesis (29.18±0.35, mean ± SEM) and longer in gastroparetics compared to non-diabetic controls (28.50±0.14 vs 27.64±0.20 GT repeats/allele, P = 0.0008). Type 2 diabetic controls had longer alleles than non-diabetic controls. In all gastroparetic groups, allele lengths were longer in African Americans compared to other racial groups, differences in the proportion of African Americans in the groups accounted for the differences between gastroparetics and controls. Diabetic gastroparetics with 1 or 2 long alleles had worse GCSI nausea sub-scores (3.30±0.23) as compared to those with 0 long alleles (2.66±0.12), P = 0.022. Conclusions Longer poly-GT repeats in the HMOX1 gene are more common in African Americans with gastroparesis. Nausea symptoms are worse in

  12. Repeat polymorphisms in the Homo sapiens heme oxygenase-1 gene in diabetic and idiopathic gastroparesis.

    Science.gov (United States)

    Gibbons, Simon J; Grover, Madhusudan; Choi, Kyoung Moo; Wadhwa, Akhilesh; Zubair, Adeel; Wilson, Laura A; Wu, Yanhong; Abell, Thomas L; Hasler, William L; Koch, Kenneth L; McCallum, Richard W; Nguyen, Linda A B; Parkman, Henry P; Sarosiek, Irene; Snape, William J; Tonascia, James; Hamilton, Frank A; Pasricha, Pankaj J; Farrugia, Gianrico

    2017-01-01

    Idiopathic and diabetic gastroparesis in Homo sapiens cause significant morbidity. Etiology or risk factors have not been clearly identified. Failure to sustain elevated heme oxygenase-1 (HO1) expression is associated with delayed gastric emptying in diabetic mice and polymorphisms in the HO1 gene (HMOX1, NCBI Gene ID:3162) are associated with worse outcomes in other diseases. Our hypothesis was that longer polyGT alleles are more common in the HMOX1 genes of individuals with gastroparesis than in controls without upper gastrointestinal motility disorders. Repeat length was determined in genomic DNA. Controls with diabetes (84 type 1, 84 type 2) and without diabetes (n = 170) were compared to diabetic gastroparetics (99 type 1, 72 type 2) and idiopathic gastroparetics (n = 234). Correlations of repeat lengths with clinical symptom sub-scores on the gastroparesis cardinal symptom index (GCSI) were done. Statistical analyses of short (32) repeat alleles and differences in allele length were used to test for associations with gastroparesis. The distribution of allele lengths was different between groups (P = 0.016). Allele lengths were longest in type 2 diabetics with gastroparesis (29.18±0.35, mean ± SEM) and longer in gastroparetics compared to non-diabetic controls (28.50±0.14 vs 27.64±0.20 GT repeats/allele, P = 0.0008). Type 2 diabetic controls had longer alleles than non-diabetic controls. In all gastroparetic groups, allele lengths were longer in African Americans compared to other racial groups, differences in the proportion of African Americans in the groups accounted for the differences between gastroparetics and controls. Diabetic gastroparetics with 1 or 2 long alleles had worse GCSI nausea sub-scores (3.30±0.23) as compared to those with 0 long alleles (2.66±0.12), P = 0.022. Longer poly-GT repeats in the HMOX1 gene are more common in African Americans with gastroparesis. Nausea symptoms are worse in subjects with longer alleles.

  13. Repeat polymorphisms in the Homo sapiens heme oxygenase-1 gene in diabetic and idiopathic gastroparesis.

    Directory of Open Access Journals (Sweden)

    Simon J Gibbons

    Full Text Available Idiopathic and diabetic gastroparesis in Homo sapiens cause significant morbidity. Etiology or risk factors have not been clearly identified. Failure to sustain elevated heme oxygenase-1 (HO1 expression is associated with delayed gastric emptying in diabetic mice and polymorphisms in the HO1 gene (HMOX1, NCBI Gene ID:3162 are associated with worse outcomes in other diseases.Our hypothesis was that longer polyGT alleles are more common in the HMOX1 genes of individuals with gastroparesis than in controls without upper gastrointestinal motility disorders.Repeat length was determined in genomic DNA. Controls with diabetes (84 type 1, 84 type 2 and without diabetes (n = 170 were compared to diabetic gastroparetics (99 type 1, 72 type 2 and idiopathic gastroparetics (n = 234. Correlations of repeat lengths with clinical symptom sub-scores on the gastroparesis cardinal symptom index (GCSI were done. Statistical analyses of short (32 repeat alleles and differences in allele length were used to test for associations with gastroparesis.The distribution of allele lengths was different between groups (P = 0.016. Allele lengths were longest in type 2 diabetics with gastroparesis (29.18±0.35, mean ± SEM and longer in gastroparetics compared to non-diabetic controls (28.50±0.14 vs 27.64±0.20 GT repeats/allele, P = 0.0008. Type 2 diabetic controls had longer alleles than non-diabetic controls. In all gastroparetic groups, allele lengths were longer in African Americans compared to other racial groups, differences in the proportion of African Americans in the groups accounted for the differences between gastroparetics and controls. Diabetic gastroparetics with 1 or 2 long alleles had worse GCSI nausea sub-scores (3.30±0.23 as compared to those with 0 long alleles (2.66±0.12, P = 0.022.Longer poly-GT repeats in the HMOX1 gene are more common in African Americans with gastroparesis. Nausea symptoms are worse in subjects with longer alleles.

  14. Planar shock focusing through perfect gas lens: First experimental demonstration

    International Nuclear Information System (INIS)

    Biamino, Laurent; Mariani, Christian; Jourdan, Georges; Houas, Lazhar; Vandenboomgaerde, Marc; Souffland, Denis

    2014-01-01

    When a shock wave crosses an interface between two materials, this interface becomes unstable and the Richtmyer-Meshkov instability develops. Such instability has been extensively studied in the planar case, and numerous results were presented during the previous workshops. But the Richtmyer-Meshkov (Richtmyer, 1960, 'Taylor Instability in Shock Acceleration of Compressible Fluids,' Commun. Pure Appl. Math., 13(2), pp. 297-319; Meshkov, 1969, 'Interface of Two Gases Accelerated by a Shock Wave,' Fluid Dyn., 4(5), pp. 101-104) instability also occurs in a spherical case where the convergence effects must be taken into account. As far as we know, no conventional (straight section) shock tube facility has been used to experimentally study the Richtmyer-Meshkov instability in spherical geometry. The idea originally proposed by Dimotakis and Samtaney (2006, 'Planar Shock Cylindrical Focusing by a Perfect-Gas Lens,' Phys. Fluid., 18(3), pp. 031705-031708) and later generalized by Vandenboomgaerde and Aymard (2011, 'Analytical Theory for Planar Shock Focusing Through Perfect Gas Lens and Shock Tube Experiment Designs,' Phys. Fluid., 23(1), pp. 016101-016113) was to retain the flexibility of a conventional shock tube to convert a planar shock wave into a cylindrical one through a perfect gas lens. This can be done when a planar shock wave passes through a shaped interface between two gases. By coupling the shape with the impedance mismatch at the interface, it is possible to generate a circular transmitted shock wave. In order to experimentally check the feasibility of this approach, we have implemented the gas lens technique on a conventional shock tube with the help of a convergent test section, an elliptic stereo lithographed grid, and a nitrocellulose membrane. First experimental sequences of Schlieren images have been obtained for an incident shock wave Mach number equal to 1.15 and an air/SF_6-shaped interface. Experimental results indicate that the shock that moves

  15. Selective propagation of mouse-passaged scrapie prions with long incubation period from a mixed prion population using GT1-7 cells.

    Directory of Open Access Journals (Sweden)

    Kohtaro Miyazawa

    Full Text Available In our previous study, we demonstrated the propagation of mouse-passaged scrapie isolates with long incubation periods (L-type derived from natural Japanese sheep scrapie cases in murine hypothalamic GT1-7 cells, along with disease-associated prion protein (PrPSc accumulation. We here analyzed the susceptibility of GT1-7 cells to scrapie prions by exposure to infected mouse brains at different passages, following interspecies transmission. Wild-type mice challenged with a natural sheep scrapie case (Kanagawa exhibited heterogeneity of transmitted scrapie prions in early passages, and this mixed population converged upon one with a short incubation period (S-type following subsequent passages. However, when GT1-7 cells were challenged with these heterologous samples, L-type prions became dominant. This study demonstrated that the susceptibility of GT1-7 cells to L-type prions was at least 105 times higher than that to S-type prions and that L-type prion-specific biological characteristics remained unchanged after serial passages in GT1-7 cells. This suggests that a GT1-7 cell culture model would be more useful for the economical and stable amplification of L-type prions at the laboratory level. Furthermore, this cell culture model might be used to selectively propagate L-type scrapie prions from a mixed prion population.

  16. The effect of S-substitution at the O6-guanine site on the structure and dynamics of a DNA oligomer containing a G:T mismatch.

    Directory of Open Access Journals (Sweden)

    Elaine Ann Moore

    Full Text Available The effect of S-substitution on the O6 guanine site of a 13-mer DNA duplex containing a G:T mismatch is studied using molecular dynamics. The structure, dynamic evolution and hydration of the S-substituted duplex are compared with those of a normal duplex, a duplex with S-substitution on guanine, but no mismatch and a duplex with just a G:T mismatch. The S-substituted mismatch leads to cell death rather than repair. One suggestion is that the G:T mismatch recognition protein recognises the S-substituted mismatch (GS:T as G:T. This leads to a cycle of futile repair ending in DNA breakage and cell death. We find that some structural features of the helix are similar for the duplex with the G:T mismatch and that with the S-substituted mismatch, but differ from the normal duplex, notably the helical twist. These differences arise from the change in the hydrogen-bonding pattern of the base pair. However a marked feature of the S-substituted G:T mismatch duplex is a very large opening. This showed considerable variability. It is suggested that this enlarged opening would lend support to an alternative model of cell death in which the mismatch protein attaches to thioguanine and activates downstream damage-response pathways. Attack on the sulphur by reactive oxygen species, also leading to cell death, would also be aided by the large, variable opening.

  17. No-signaling, perfect bipartite dichotomic correlations and local randomness

    International Nuclear Information System (INIS)

    Seevinck, M. P.

    2011-01-01

    The no-signaling constraint on bi-partite correlations is reviewed. It is shown that in order to obtain non-trivial Bell-type inequalities that discern no-signaling correlations from more general ones, one must go beyond considering expectation values of products of observables only. A new set of nontrivial no-signaling inequalities is derived which have a remarkably close resemblance to the CHSH inequality, yet are fundamentally different. A set of inequalities by Roy and Singh and Avis et al., which is claimed to be useful for discerning no-signaling correlations, is shown to be trivially satisfied by any correlation whatsoever. Finally, using the set of newly derived no-signaling inequalities a result with potential cryptographic consequences is proven: if different parties use identical devices, then, once they have perfect correlations at spacelike separation between dichotomic observables, they know that because of no-signaling the local marginals cannot but be completely random.

  18. Perfect synchronization in networks of phase-frustrated oscillators

    Science.gov (United States)

    Kundu, Prosenjit; Hens, Chittaranjan; Barzel, Baruch; Pal, Pinaki

    2017-11-01

    Synchronizing phase-frustrated Kuramoto oscillators, a challenge that has found applications from neuronal networks to the power grid, is an eluding problem, as even small phase lags cause the oscillators to avoid synchronization. Here we show, constructively, how to strategically select the optimal frequency set, capturing the natural frequencies of all oscillators, for a given network and phase lags, that will ensure perfect synchronization. We find that high levels of synchronization are sustained in the vicinity of the optimal set, allowing for some level of deviation in the frequencies without significant degradation of synchronization. Demonstrating our results on first- and second-order phase-frustrated Kuramoto dynamics, we implement them on both model and real power grid networks, showing how to achieve synchronization in a phase-frustrated environment.

  19. Quark-Gluon Soup -- The Perfectly Liquid Phase of QCD

    Science.gov (United States)

    Heinz, Ulrich

    2015-03-01

    At temperatures above about 150 MeV and energy densities exceeding 500 MeV/fm3, quarks and gluons exist in the form of a plasma of free color charges that is about 1000 times hotter and a billion times denser than any other plasma ever created in the laboratory. This quark-gluon plasma (QGP) turns out to be strongly coupled, flowing like a liquid. About 35 years ago, the nuclear physics community started a program of relativistic heavy-ion collisions with the goal of producing and studying QGP under controlled laboratory conditions. This article recounts the story of its successful creation in collider experiments at Brookhaven National Laboratory and CERN and the subsequent discovery of its almost perfectly liquid nature, and reports on the recent quantitatively precise determination of its thermodynamic and transport properties.

  20. Cosmological coevolution of Yang-Mills fields and perfect fluids

    International Nuclear Information System (INIS)

    Barrow, John D.; Jin, Yoshida; Maeda, Kei-ichi

    2005-01-01

    We study the coevolution of Yang-Mills fields and perfect fluids in Bianchi type I universes. We investigate numerically the evolution of the universe and the Yang-Mills fields during the radiation and dust eras of a universe that is almost isotropic. The Yang-Mills field undergoes small amplitude chaotic oscillations, as do the three expansion scale factors which are also displayed by the expansion scale factors of the universe. The results of the numerical simulations are interpreted analytically and compared with past studies of the cosmological evolution of magnetic fields in radiation and dust universes. We find that, whereas magnetic universes are strongly constrained by the microwave background anisotropy, Yang-Mills universes are principally constrained by primordial nucleosynthesis but the bound is comparatively weak with Ω YM rad

  1. Simulation of MILD combustion using Perfectly Stirred Reactor model

    KAUST Repository

    Chen, Z.

    2016-07-06

    A simple model based on a Perfectly Stirred Reactor (PSR) is proposed for moderate or intense low-oxygen dilution (MILD) combustion. The PSR calculation is performed covering the entire flammability range and the tabulated chemistry approach is used with a presumed joint probability density function (PDF). The jet, in hot and diluted coflow experimental set-up under MILD conditions, is simulated using this reactor model for two oxygen dilution levels. The computed results for mean temperature, major and minor species mass fractions are compared with the experimental data and simulation results obtained recently using a multi-environment transported PDF approach. Overall, a good agreement is observed at three different axial locations for these comparisons despite the over-predicted peak value of CO formation. This suggests that MILD combustion can be effectively modelled by the proposed PSR model with lower computational cost.

  2. Perfectly matched layer for the time domain finite element method

    International Nuclear Information System (INIS)

    Rylander, Thomas; Jin Jianming

    2004-01-01

    A new perfectly matched layer (PML) formulation for the time domain finite element method is described and tested for Maxwell's equations. In particular, we focus on the time integration scheme which is based on Galerkin's method with a temporally piecewise linear expansion of the electric field. The time stepping scheme is constructed by forming a linear combination of exact and trapezoidal integration applied to the temporal weak form, which reduces to the well-known Newmark scheme in the case without PML. Extensive numerical tests on scattering from infinitely long metal cylinders in two dimensions show good accuracy and no signs of instabilities. For a circular cylinder, the proposed scheme indicates the expected second order convergence toward the analytic solution and gives less than 2% root-mean-square error in the bistatic radar cross section (RCS) for resolutions with more than 10 points per wavelength. An ogival cylinder, which has sharp corners supporting field singularities, shows similar accuracy in the monostatic RCS

  3. Gravitational perfect fluid collapse in Gauss-Bonnet gravity

    Energy Technology Data Exchange (ETDEWEB)

    Abbas, G.; Tahir, M. [The Islamia University of Bahawalpur, Department of Mathematics, Bahawalpur (Pakistan)

    2017-08-15

    The Einstein Gauss-Bonnet theory of gravity is the low-energy limit of heterotic super-symmetric string theory. This paper deals with gravitational collapse of a perfect fluid in Einstein-Gauss-Bonnet gravity by considering the Lemaitre-Tolman-Bondi metric. For this purpose, the closed form of the exact solution of the equations of motion has been determined by using the conservation of the stress-energy tensor and the condition of marginally bound shells. It has been investigated that the presence of a Gauss-Bonnet coupling term α > 0 and the pressure of the fluid modifies the structure and time formation of singularity. In this analysis a singularity forms earlier than a horizon, so the end state of the collapse is a naked singularity depending on the initial data. But this singularity is weak and timelike, which goes against the investigation of general relativity. (orig.)

  4. Mathematical theories of classical particle channeling in perfect crystals

    International Nuclear Information System (INIS)

    Dumas, H. Scott

    2005-01-01

    We present an overview of our work on rigorous mathematical theories of channeling for highly energetic positive particles moving in classical perfect crystal potentials. Developed over the last two decades, these theories include: (i) a comprehensive, highly mathematical theory based on Nekhoroshev's theorem which embraces both axial and planar channeling as well as certain non-channeling particle motions (ii) a theory of axial channeling for relativistic particles based on a single-phase averaging method for ordinary differential equations and (iii) a theory of planar channeling for relativistic particles based on a two-phase averaging method for ordinary differential equations. Here we touch briefly on (i) and (ii), then focus on (iii). Together these theories place Lindhard's continuum model approximations on a firm mathematical foundation, and should serve as the starting point for more refined mathematical treatments of channeling

  5. Expanding perfect fluid generalizations of the C metric

    International Nuclear Information System (INIS)

    Wylleman, Lode; Beke, David

    2010-01-01

    Petrov type D gravitational fields, generated by a perfect fluid with spatially homogeneous energy density and with flow lines which form a nonshearing and nonrotating timelike congruence, are reexamined. It turns out that the anisotropic such spacetimes, which comprise the vacuum C metric as a limit case, can have nonzero expansion, contrary to the conclusion in the original investigation by Barnes [A. Barnes, Gen. Relativ. Gravit. 4, 105 (1973).]. Apart from the static members, this class consists of cosmological models with precisely one symmetry. The general line element is constructed and some important properties are discussed. It is also shown that purely electric Petrov type D vacuum spacetimes admit shear-free normal timelike congruences everywhere, even in the nonstatic regions. This result incited to deduce intrinsic, easily testable criteria regarding shear-free normality and staticity of Petrov type D spacetimes in general, which are added in an appendix.

  6. On perfect fluids and black holes in static equilibrium

    Energy Technology Data Exchange (ETDEWEB)

    Carrasco, Alberto; Mars, Marc; Simon, Walter [Facultad de Ciencias, Universidad de Salamanca, Plaza de la Merced s/n, 37008 Salamanca (Spain)

    2007-05-15

    Proofs of spherical symmetry of static black holes and of spherical symmetry of static perfect fluids normally require, a priori, 'black holes only' or 'fluid only'. In a recent paper Shiromizu, Yamada and Yoshino admit a priori (and exclude) coexistence of fluids and holes. This work assumes connectedness of the fluid region and the same assumptions on the equation of state as earlier papers on the 'fluid only' case, and requires in addition an upper bound for the fluid mass in terms of the black holes masses. We discuss this paper. As a new result we show that there cannot exist static fluid shells (i.e. fluid regions of the topology of an annulus) even if one a priori admits, inside and outside the shell, any arrangement of black holes or additional matter which satisfies the energy condition.

  7. On perfect fluids and black holes in static equilibrium

    International Nuclear Information System (INIS)

    Carrasco, Alberto; Mars, Marc; Simon, Walter

    2007-01-01

    Proofs of spherical symmetry of static black holes and of spherical symmetry of static perfect fluids normally require, a priori, 'black holes only' or 'fluid only'. In a recent paper Shiromizu, Yamada and Yoshino admit a priori (and exclude) coexistence of fluids and holes. This work assumes connectedness of the fluid region and the same assumptions on the equation of state as earlier papers on the 'fluid only' case, and requires in addition an upper bound for the fluid mass in terms of the black holes masses. We discuss this paper. As a new result we show that there cannot exist static fluid shells (i.e. fluid regions of the topology of an annulus) even if one a priori admits, inside and outside the shell, any arrangement of black holes or additional matter which satisfies the energy condition

  8. Efficient and stable perfectly matched layer for CEM

    KAUST Repository

    Duru, Kenneth

    2014-02-01

    An efficient unsplit perfectly matched layer for numerical simulation of electromagnetic waves in unbounded domains is derived via a complex change of variables. In order to surround a Cartesian grid with the PML, the time-dependent PML requires only one (scalar) auxiliary variable in two space dimensions and six (scalar) auxiliary variables in three space dimensions. It is therefore cheap and straightforward to implement. We use Fourier and energy methods to prove the stability of the PML. We extend the stability result to a semi-discrete PML approximated by central finite differences of arbitrary order of accuracy and to a fully discrete problem for the \\'Leap-Frog\\' schemes. This makes precise the usefulness of the derived PML model for longtime simulations. Numerical experiments are presented, illustrating the accuracy and stability of the PML. © 2013 IMACS.

  9. Perfect fluid models in noncomoving observational spherical coordinates

    International Nuclear Information System (INIS)

    Ishak, Mustapha

    2004-01-01

    We use null spherical (observational) coordinates to describe a class of inhomogeneous cosmological models. The proposed cosmological construction is based on the observer past null cone. A known difficulty in using inhomogeneous models is that the null geodesic equation is not integrable in general. Our choice of null coordinates solves the radial ingoing null geodesic by construction. Furthermore, we use an approach where the velocity field is uniquely calculated from the metric rather than put in by hand. Conveniently, this allows us to explore models in a noncomoving frame of reference. In this frame, we find that the velocity field has shear, acceleration, and expansion rate in general. We show that a comoving frame is not compatible with expanding perfect fluid models in the coordinates proposed and dust models are simply not possible. We describe the models in a noncomoving frame. We use the dust models in a noncomoving frame to outline a fitting procedure

  10. Wideband perfect coherent absorber based on white-light cavity

    Science.gov (United States)

    Kotlicki, Omer; Scheuer, Jacob

    2015-03-01

    Coherent Perfect Absorbers (CPAs) are optical cavities which can be described as time-reversed lasers where light waves that enter the cavity, coherently interfere and react with the intra-cavity losses to yield perfect absorption. In contrast to lasers, which benefit from high coherency and narrow spectral linewidths, for absorbers these properties are often undesirable as absorption at a single frequency is highly susceptible to spectral noise and inappropriate for most practical applications. Recently, a new class of cavities, characterized by a spectrally wide resonance has been proposed. Such resonators, often referred to as White Light Cavities (WLCs), include an intra-cavity superluminal phase element, designed to provide a phase response with a slope that is opposite in sign and equal in magnitude to that of light propagation through the empty cavity. Consequently, the resonance phase condition in WLCs is satisfied over a band of frequencies providing a spectrally wide resonance. WLCs have drawn much attention due to their attractiveness for various applications such as ultra-sensitive sensors and optical buffering components. Nevertheless, WLCs exhibit inherent losses that are often undesirable. Here we introduce a simple wideband CPA device that is based on the WLC concept along with a complete analytical analysis. We present analytical and FDTD simulations of a practical, highly compact (12µm), Silicon based WLC-CPA that exhibits a flat and wide absorption profile (40nm) and demonstrate its usefulness as an optical pulse terminator (>35db isolation) and an all optical modulator that span the entire C-Band and exhibit high immunity to spectral noise.

  11. Perfect fluid tori orbiting Kehagias-Sfetsos naked singularities

    Science.gov (United States)

    Stuchlík, Z.; Pugliese, D.; Schee, J.; Kučáková, H.

    2015-09-01

    We construct perfect fluid tori in the field of the Kehagias-Sfetsos (K-S) naked singularities. These are spherically symmetric vacuum solutions of the modified Hořava quantum gravity, characterized by a dimensionless parameter ω M^2, combining the gravitational mass parameter M of the spacetime with the Hořava parameter ω reflecting the role of the quantum corrections. In dependence on the value of ω M^2, the K-S naked singularities demonstrate a variety of qualitatively different behavior of their circular geodesics that is fully reflected in the properties of the toroidal structures, demonstrating clear distinction to the properties of the torii in the Schwarzschild spacetimes. In all of the K-S naked singularity spacetimes the tori are located above an "antigravity" sphere where matter can stay in a stable equilibrium position, which is relevant for the stability of the orbiting fluid toroidal accretion structures. The signature of the K-S naked singularity is given by the properties of marginally stable tori orbiting with the uniform distribution of the specific angular momentum of the fluid, l= const. In the K-S naked singularity spacetimes with ω M^2 > 0.2811, doubled tori with the same l= const can exist; mass transfer between the outer torus and the inner one is possible under appropriate conditions, while only outflow to the outer space is allowed in complementary conditions. In the K-S spacetimes with ω M^2 < 0.2811, accretion from cusped perfect fluid tori is not possible due to the non-existence of unstable circular geodesics.

  12. Perfect fluid tori orbiting Kehagias-Sfetsos naked singularities

    Energy Technology Data Exchange (ETDEWEB)

    Stuchlik, Z.; Pugliese, D.; Schee, J.; Kucakova, H. [Silesian University in Opava, Faculty of Philosophy and Science, Institute of Physics and Research Centre of Theoretical Physics and Astrophysics, Opava (Czech Republic)

    2015-09-15

    We construct perfect fluid tori in the field of the Kehagias-Sfetsos (K-S) naked singularities. These are spherically symmetric vacuum solutions of the modified Horava quantum gravity, characterized by a dimensionless parameter ωM{sup 2}, combining the gravitational mass parameter M of the spacetime with the Horava parameter ω, reflecting the role of the quantum corrections. In dependence on the value of ωM{sup 2}, the K-S naked singularities demonstrate a variety of qualitatively different behavior of their circular geodesics that is fully reflected in the properties of the toroidal structures, demonstrating clear distinction to the properties of the torii in the Schwarzschild spacetimes. In all of the K-S naked singularity spacetimes the tori are located above an @gantigravity@h sphere where matter can stay in a stable equilibrium position, which is relevant for the stability of the orbiting fluid toroidal accretion structures. The signature of the K-S naked singularity is given by the properties of marginally stable tori orbiting with the uniform distribution of the specific angular momentum of the fluid, l = const. In the K-S naked singularity spacetimes with ωM{sup 2} > 0.2811, doubled tori with the same l = const can exist; mass transfer between the outer torus and the inner one is possible under appropriate conditions, while only outflow to the outer space is allowed in complementary conditions. In the K-S spacetimes with ωM{sup 2} < 0.2811, accretion from cusped perfect fluid tori is not possible due to the non-existence of unstable circular geodesics. (orig.)

  13. If Practice Makes Perfect, Why Does Familiarity Breed Contempt?

    Science.gov (United States)

    McCreesh, Bernadine

    1999-01-01

    Investigated whether college-level second language learners would learn better from an exercise in which they repeated the original sentence they got wrong or when presented with a different, parallel sentence. Results found that some students preferred to redo the same sentence, while others preferred a different one. One main difference was in…

  14. Estrogen modulates potassium currents and expression of the Kv4.2 subunit in GT1-7 cells.

    Science.gov (United States)

    Farkas, Imre; Varju, Patricia; Liposits, Zsolt

    2007-03-01

    The proper maintenance of reproduction requires the pulsatile secretion of gonadotropin-releasing hormone (GnRH), which is ensured by synchronized periodic firing of multiple GnRH neurons. Both hormone secretion and electrophysiological properties of GnRH cells are influenced by estrogen. The impact of 17beta-estradiol treatment on the function of voltage gated A- and K-type potassium channels, known modulators of firing rate, was therefore examined in our experiments using immortalized GnRH-producing GT1-7 neurons. Whole cell patch clamp recordings showed the absence of the A-type current in GT1-7 cells cultured in estrogen-free medium and after 8h 17beta-estradiol treatment. Exposure of the cells to 17beta-estradiol for 24 and 48 h, respectively, resulted in the appearance of the A-type current. The induction of the A-type current by 17beta-estradiol was dose-related (50 pM to 15 nM range). In contrast, the K-type potassium current was apparent in the estrogen-free environment and 17beta-estradiol administration significantly decreased its amplitude. Co-administration of 17beta-estradiol and estrogen receptor blocker, Faslodex (ICI 182,780; 1 microM) abolished the occurrence of the A-type current. Real-time PCR data demonstrated that expression of the Kv4.2 subunit of the A-type channel was low at 0, 0.5, 2 and 8h, peaked at 24h and diminished at 48 h 17beta-estradiol treatment (15 nM). These data indicate that potassium channels of GT1-7 neurons are regulated by estrogen a mechanism that might contribute to modulation of firing rate and hormone secretion in GnRH neurons.

  15. Analysis of repeated measures data

    CERN Document Server

    Islam, M Ataharul

    2017-01-01

    This book presents a broad range of statistical techniques to address emerging needs in the field of repeated measures. It also provides a comprehensive overview of extensions of generalized linear models for the bivariate exponential family of distributions, which represent a new development in analysing repeated measures data. The demand for statistical models for correlated outcomes has grown rapidly recently, mainly due to presence of two types of underlying associations: associations between outcomes, and associations between explanatory variables and outcomes. The book systematically addresses key problems arising in the modelling of repeated measures data, bearing in mind those factors that play a major role in estimating the underlying relationships between covariates and outcome variables for correlated outcome data. In addition, it presents new approaches to addressing current challenges in the field of repeated measures and models based on conditional and joint probabilities. Markov models of first...

  16. Repeated DNA sequences in fungi

    Energy Technology Data Exchange (ETDEWEB)

    Dutta, S K

    1974-11-01

    Several fungal species, representatives of all broad groups like basidiomycetes, ascomycetes and phycomycetes, were examined for the nature of repeated DNA sequences by DNA:DNA reassociation studies using hydroxyapatite chromatography. All of the fungal species tested contained 10 to 20 percent repeated DNA sequences. There are approximately 100 to 110 copies of repeated DNA sequences of approximately 4 x 10/sup 7/ daltons piece size of each. Repeated DNA sequence homoduplexes showed on average 5/sup 0/C difference of T/sub e/50 (temperature at which 50 percent duplexes dissociate) values from the corresponding homoduplexes of unfractionated whole DNA. It is suggested that a part of repetitive sequences in fungi constitutes mitochondrial DNA and a part of it constitutes nuclear DNA. (auth)

  17. Performance evaluations of advanced massively parallel platforms based on gyrokinetic toroidal five-dimensional Eulerian code GT5D

    International Nuclear Information System (INIS)

    Idomura, Yasuhiro; Jolliet, Sebastien

    2010-01-01

    A gyrokinetic toroidal five dimensional Eulerian code GT5D is ported on six advanced massively parallel platforms and comprehensive benchmark tests are performed. A parallelisation technique based on physical properties of the gyrokinetic equation is presented. By extending the parallelisation technique with a hybrid parallel model, the scalability of the code is improved on platforms with multi-core processors. In the benchmark tests, a good salability is confirmed up to several thousands cores on every platforms, and the maximum sustained performance of ∼18.6 Tflops is achieved using 16384 cores of BX900. (author)

  18. Operational, control and protective system transient analyses of the closed-cycle GT-HTGR power plant

    International Nuclear Information System (INIS)

    Openshaw, F.L.; Chan, T.W.

    1980-07-01

    This paper presents a description of the analyses of the control/protective system preliminary designs for the gas turbine high-temperature gas-cooled reactor (GT-HTGR) power plant. The control system is designed to regulate reactor power, control electric load and turbine speed, control the temperature of the helium delivered to the turbines, and control thermal transients experienced by the system components. In addition, it provides the required control programming for startup, shutdown, load ramp, and other expected operations. The control system also handles conditions imposed on the system during upset and emergency conditions such as loop trip, reactor trip, or electrical load rejection

  19. GT Biplot Analysis for Silage Potential, Nutritive Value, Gas and Methane Production of Stay-Green Grain Sorghum Shoots

    OpenAIRE

    Kaplan, Mahmut; Arslan, Mustafa; Kale, Hasan; Kara, Kanber; Kokten, Kagan

    2017-01-01

    Abstract This study was conducted to investigate the possible silage of stay-green sorghum genotypes using GT biplot analysis. Following the grain harvest, 41 sorghum genotypes were chopped to make silage. Biochemical analyses were performed after 60 d of silage. The results revealed that green herbage yields varied between 13.40-65.96 t ha−1, pH between 3.92-4.25, dry matter ratios between 24.26-35.83%, crude protein ratios between 3.44-7.03%, acid detergent fiber (ADF) ratios between 27.46-...

  20. Typological and dimensional approach at comparing the Giessen Test (GT) with the NEO-Five-Factor-Inventory (NEO-FFI)

    Science.gov (United States)

    Roth, Marcus; Körner, Annett; Herzberg, Philipp Yorck

    2008-01-01

    Objectives: This article reports comparisons of the Giessen Test (GT) with the NEO-Five-Factor-Inventory (NEO-FFI) based on a dimensional as well as on a typological approach. Method: Data were collected from 1673 subjects (aged between 18 and 96 years) constituting a representative sample of the German population. Results: The results indicate only moderate agreement (ranging from .25 to .61) between the subscales of the two personality inventories. The correspondence seems to be somewhat higher, when the typological approach was used instead of the dimensional approach. Conclusions: The typological approach is less dependent on the underlying questionnaires and provides a useful extension of the dimensional approach. PMID:19742276

  1. Visualisasi Hasil Mesin Uji Tarik Gotech GT-7010-D2E dalam Bentuk Grafik secara Real Time

    OpenAIRE

    Anggoro Suryo Pramudyo; Andi Rachmansyah; Suhendar

    2014-01-01

    Gotech GT-7010-D2E is a tensile testing machine used in Metallurgical Engineering Laboratory UNTIRTA. The machine are used both for practical and Materials Engineering specimen testing demanded by several industries. The machine can perform tensile tests well, but for the analysis is done manually, so it requires a lot of time and accuracy of the analysis results are not very accurate. Therefore, it’s needed a software that can analyze the results of the tensile test in the form of graphs in ...

  2. Lower crustal section of the Oman Ophiolite drilled in Hole GT1A, ICDP Oman Drilling Project

    Science.gov (United States)

    Umino, S.; Kelemen, P. B.; Matter, J. M.; Coggon, J. A.; Takazawa, E.; Michibayashi, K.; Teagle, D. A. H.

    2017-12-01

    Hole GT1A (22° 53.535'N, 58° 30.904'E) was drilled by the Oman Drilling Project (OmDP) into GT1A of the Samail ophiolite, Oman. OmDP is an international collaboration supported by the International Continental Scientific Drilling Program, the Deep Carbon Observatory, NSF, IODP, JAMSTEC, and the European, Japanese, German and Swiss Science Foundations, with in-kind support in Oman from the Ministry of Regional Municipalities and Water Resources, Public Authority of Mining, Sultan Qaboos University, and the German University of Technology. Hole GT1A was diamond cored in 22 Jan to 08 Feb 2017 to a total depth of 403.05 m. The outer surfaces of the cores were imaged and described on site before being curated, boxed and shipped to the IODP drill ship Chikyu, where they underwent comprehensive visual and instrumental analysis. Hole GT1A drilled the lower crustal section in the southern Oman Ophiolite and recovered 401.52 m of total cores (99.6% recovery). The main lithology is dominated by olivine gabbro (65.9%), followed in abundance by olivine-bearing gabbro (21.5%) and olivine melagabbro (3.9%). Minor rock types are orthopyroxene-bearing olivine gabbro (2.4%), oxide-bearing olivine gabbro (1.5%), gabbro (1.1%), anorthositic gabbro (1%), troctolitic gabbro (0.8%); orthopyroxene-bearing gabbro (0.5%), gabbronorite (0.3%); and dunite (0.3%). These rocks are divided into Lithologic Unit I to VII at 26.62 m, 88.16 m, 104.72 m, 154.04 m, 215.22 m, 306.94 m in Chikyu Curated Depth in descending order; Unit I and II consist of medium-grained olivine gabbro with lower olivine abundance in Unit II. Unit III is medium-grained olivine melagabbros, marked by an increase in olivine. Unit IV is relatively homogenous medium-grained olivine gabbros with granular textures. Unit V is identified by the appearance of fine-grained gabbros, but the major rocktypes are medium grained olivine gabbros. Unit VI is medium-grained olivine gabbro, marked by appearance of orthopyroxene. Unit VII

  3. Colletotrilactam A-D, novel lactams from Colletotrichum gloeosporioides GT-7, a fungal endophyte of Uncaria rhynchophylla.

    Science.gov (United States)

    Wei, Bo; Yang, Zhong-Duo; Chen, Xiao-Wei; Zhou, Shuang-Yan; Yu, Hai-Tao; Sun, Jing-Yun; Yao, Xiao-Jun; Wang, Yong-Gang; Xue, Hong-Yan

    2016-09-01

    Four novel lactams, colletotrilactam A-D (1-4), along with six known compounds (5-10) were isolated from the culture broth of Colletotrichum gloeosporioides GT-7, a fungal endophyte of Uncaria rhynchophylla. The structures of these compounds were elucidated by comprehensive NMR spectroscopy. Isolates were tested for monoamine oxidase (MAO) inhibitory activity and compound 9 showed potent MAO inhibitory activity with IC50 value of 8.93±0.34μg/mL, when the IC50 value of iproniazid as a standard was 1.80±0.5μg/mL. Copyright © 2016 Elsevier B.V. All rights reserved.

  4. Evaluation of Cathode Air Flow Transients in a SOFC/GT Hybrid System Using Hardware in the Loop Simulation.

    Science.gov (United States)

    Zhou, Nana; Yang, Chen; Tucker, David

    2015-02-01

    Thermal management in the fuel cell component of a direct fired solid oxide fuel cell gas turbine (SOFC/GT) hybrid power system can be improved by effective management and control of the cathode airflow. The disturbances of the cathode airflow were accomplished by diverting air around the fuel cell system through the manipulation of a hot-air bypass valve in open loop experiments, using a hardware-based simulation facility designed and built by the U.S. Department of Energy, National Energy Technology Laboratory (NETL). The dynamic responses of the fuel cell component and hardware component of the hybrid system were studied in this paper.

  5. Fostering repeat donations in Ghana.

    Science.gov (United States)

    Owusu-Ofori, S; Asenso-Mensah, K; Boateng, P; Sarkodie, F; Allain, J-P

    2010-01-01

    Most African countries are challenged in recruiting and retaining voluntary blood donors by cost and other complexities and in establishing and implementing national blood policies. The availability of replacement donors who are a cheaper source of blood has not enhanced repeat voluntary donor initiatives. An overview of activities for recruiting and retaining voluntary blood donors was carried out. Donor records from mobile sessions were reviewed from 2002 to 2008. A total of 71,701 blood donations; 45,515 (63.5%) being voluntary donations with 11,680 (25%) repeat donations were collected during the study period. Donations from schools and colleges contributed a steady 60% of total voluntary whilst radio station blood drives increased contribution from 10 to 27%. Though Muslim population is less than 20%, blood collection was above the 30-donation cost-effectiveness threshold with a repeat donation trend reaching 60%. In contrast Christian worshippers provided donations. Repeat donation trends amongst school donors and radio blood drives were 20% and 70% respectively. Repeat donations rates have been variable amongst different blood donor groups in Kumasi, Ghana. The impact of community leaders in propagating altruism cannot be overemphasized. Programs aiming at motivating replacement donors to be repeat donors should be developed and assessed. Copyright 2009 The International Association for Biologicals. All rights reserved.

  6. Conservative Sample Size Determination for Repeated Measures Analysis of Covariance.

    Science.gov (United States)

    Morgan, Timothy M; Case, L Douglas

    2013-07-05

    In the design of a randomized clinical trial with one pre and multiple post randomized assessments of the outcome variable, one needs to account for the repeated measures in determining the appropriate sample size. Unfortunately, one seldom has a good estimate of the variance of the outcome measure, let alone the correlations among the measurements over time. We show how sample sizes can be calculated by making conservative assumptions regarding the correlations for a variety of covariance structures. The most conservative choice for the correlation depends on the covariance structure and the number of repeated measures. In the absence of good estimates of the correlations, the sample size is often based on a two-sample t-test, making the 'ultra' conservative and unrealistic assumption that there are zero correlations between the baseline and follow-up measures while at the same time assuming there are perfect correlations between the follow-up measures. Compared to the case of taking a single measurement, substantial savings in sample size can be realized by accounting for the repeated measures, even with very conservative assumptions regarding the parameters of the assumed correlation matrix. Assuming compound symmetry, the sample size from the two-sample t-test calculation can be reduced at least 44%, 56%, and 61% for repeated measures analysis of covariance by taking 2, 3, and 4 follow-up measures, respectively. The results offer a rational basis for determining a fairly conservative, yet efficient, sample size for clinical trials with repeated measures and a baseline value.

  7. Optimization of preparation of skilled wrestlers by perfection of method of the special preparation

    Directory of Open Access Journals (Sweden)

    Ogar' G.O.

    2009-12-01

    Full Text Available The author method of the special physical preparation of skilled fighters is presented. A method carries stage-by-stage character. On the first stage effectively to conduct the accented power training. On the second stage - to perfect explosive force. Tasks of the third stage are perfection of speed force and lactate component of energy supply. On the fourth stage the special is perfected speed-power endurance. The fifth stage coincides with beginning of competition period of macrocycle.

  8. Creating the Perfect Umbilicus: A Systematic Review of Recent Literature.

    Science.gov (United States)

    Joseph, Walter J; Sinno, Sammy; Brownstone, Nicholas D; Mirrer, Joshua; Thanik, Vishal D

    2016-06-01

    The aim of this study was to perform an updated systematic review of the literature over the last 10 years, analyzing and comparing the many published techniques with the hope of providing plastic surgeons with a new standard in creating the perfect umbilicus in the setting of both abdominoplasty and abdominally based free-flap breast reconstruction. An initial search using the PubMed online database with the keyword "umbilicoplasty" was performed. These results were filtered to only include articles published within the last 10 years. The remaining articles were thoroughly reviewed by the authors and only those pertaining to techniques for umbilicoplasty in the setting of abdominoplasty and abdominally based free flap were included. Of the 10 unique techniques yielded by our search, 9/10 (90 %) initially incised the native umbilicus with a round, oval, or vertical ellipse pattern. Of the 9 techniques that initially perform a round incision, 4 of them (44.4 %) later modify the round umbilicus with either an inferior or superior excision to create either a "U"- or "inverted U"-shaped umbilicus. In terms of the shape of the incision made in the abdominal flap for umbilical reinsertion, the most common were either a round incision or an inverted "V" or "U," both of which accounted for 4/10 (40 %) and 3/10 (30 %), respectively. Almost all of the studies (8/10; 80 %) describe "defatting" or trimming of the subcutaneous adipose tissue around the incision to create a periumbilical concavity following inset of the umbilicus. 4/10 (40 %) of the techniques describe suturing the dermis of the umbilical skin to rectus fascia. Furthermore, 3/10 (30 %) advise that stalk plication is a necessary step to their technique. 7/9 techniques (77.8 %) preferred nondissolvable sutures for skin closure, with nylon being the most common suture material used. Only 2/9 (22.2 %) used dissolvable sutures. Although future studies are necessary, it is our hope that this systematic

  9. Hysteresis of magnetostructural transitions: Repeatable and non-repeatable processes

    Science.gov (United States)

    Provenzano, Virgil; Della Torre, Edward; Bennett, Lawrence H.; ElBidweihy, Hatem

    2014-02-01

    The Gd5Ge2Si2 alloy and the off-stoichiometric Ni50Mn35In15 Heusler alloy belong to a special class of metallic materials that exhibit first-order magnetostructural transitions near room temperature. The magnetic properties of this class of materials have been extensively studied due to their interesting magnetic behavior and their potential for a number of technological applications such as refrigerants for near-room-temperature magnetic refrigeration. The thermally driven first-order transitions in these materials can be field-induced in the reverse order by applying a strong enough field. The field-induced transitions are typically accompanied by the presence of large magnetic hysteresis, the characteristics of which are a complicated function of temperature, field, and magneto-thermal history. In this study we show that the virgin curve, the major loop, and sequentially measured MH loops are the results of both repeatable and non-repeatable processes, in which the starting magnetostructural state, prior to the cycling of field, plays a major role. Using the Gd5Ge2Si2 and Ni50Mn35In15 alloys, as model materials, we show that a starting single phase state results in fully repeatable processes and large magnetic hysteresis, whereas a mixed phase starting state results in non-repeatable processes and smaller hysteresis.

  10. Hysteresis of magnetostructural transitions: Repeatable and non-repeatable processes

    International Nuclear Information System (INIS)

    Provenzano, Virgil; Della Torre, Edward; Bennett, Lawrence H.; ElBidweihy, Hatem

    2014-01-01

    The Gd 5 Ge 2 Si 2 alloy and the off-stoichiometric Ni 50 Mn 35 In 15 Heusler alloy belong to a special class of metallic materials that exhibit first-order magnetostructural transitions near room temperature. The magnetic properties of this class of materials have been extensively studied due to their interesting magnetic behavior and their potential for a number of technological applications such as refrigerants for near-room-temperature magnetic refrigeration. The thermally driven first-order transitions in these materials can be field-induced in the reverse order by applying a strong enough field. The field-induced transitions are typically accompanied by the presence of large magnetic hysteresis, the characteristics of which are a complicated function of temperature, field, and magneto-thermal history. In this study we show that the virgin curve, the major loop, and sequentially measured MH loops are the results of both repeatable and non-repeatable processes, in which the starting magnetostructural state, prior to the cycling of field, plays a major role. Using the Gd 5 Ge 2 Si 2 and Ni 50 Mn 35 In 15 alloys, as model materials, we show that a starting single phase state results in fully repeatable processes and large magnetic hysteresis, whereas a mixed phase starting state results in non-repeatable processes and smaller hysteresis

  11. Search for a perfect generator of random numbers

    International Nuclear Information System (INIS)

    Musyck, E.

    1977-01-01

    Theoretical tests have been carried out by COVEYOU and MAC PHERSON to verify the applications of the LEHMER algorithm. In a similar way, a theoretical method is proposed to evaluate in a rigorous way the random character of numbers generated by a shift register. This theory introduces the concept of ''degree of randomness'' of the elements, taken in a definite order, of a shift register. It permits making the judicious choice of the elements of the shift register which will produce the bits of the random numbers. On the other hand, a calculation method is developed in order to verify the primitive character of any shift register of high complexity. A new test, called ''slice test'', of empirical and theoretical use is also described; it constitutes a significant contribution to the understanding of certain properties of pseudo-random sequences. As a practical example, a random number generator structure formed with 32 bits, built out of a shift register with 61 elements and 60 modulo-2 adder circuits was made. The author is convinced that this generator can be considered to be practically perfect for all empirical applications of random numbers, particularly for the solution of Monte-Carlo problems. (author)

  12. Measuring Individual Differences in the Perfect Automation Schema.

    Science.gov (United States)

    Merritt, Stephanie M; Unnerstall, Jennifer L; Lee, Deborah; Huber, Kelli

    2015-08-01

    A self-report measure of the perfect automation schema (PAS) is developed and tested. Researchers have hypothesized that the extent to which users possess a PAS is associated with greater decreases in trust after users encounter automation errors. However, no measure of the PAS currently exists. We developed a self-report measure assessing two proposed PAS factors: high expectations and all-or-none thinking about automation performance. In two studies, participants responded to our PAS measure, interacted with imperfect automated aids, and reported trust. Each of the two PAS measure factors demonstrated fit to the hypothesized factor structure and convergent and discriminant validity when compared with propensity to trust machines and trust in a specific aid. However, the high expectations and all-or-none thinking scales showed low intercorrelations and differential relationships with outcomes, suggesting that they might best be considered two separate constructs rather than two subfactors of the PAS. All-or-none thinking had significant associations with decreases in trust following aid errors, whereas high expectations did not. Results therefore suggest that the all-or-none thinking scale may best represent the PAS construct. Our PAS measure (specifically, the all-or-none thinking scale) significantly predicted the severe trust decreases thought to be associated with high PAS. Further, it demonstrated acceptable psychometric properties across two samples. This measure may be used in future work to assess levels of PAS in users of automated systems in either research or applied settings. © 2015, Human Factors and Ergonomics Society.

  13. Kantowski-Sachs Einstein-æther perfect fluid models

    Energy Technology Data Exchange (ETDEWEB)

    Latta, Joey [Department of Mathematics and Statistics, Dalhousie University, Halifax, Nova Scotia, B3H 3J5 (Canada); Leon, Genly [Instituto de Física, Pontificia Universidad de Católica de Valparaíso, Casilla 4950, Valparaíso (Chile); Paliathanasis, Andronikos, E-mail: lattaj@mathstat.dal.ca, E-mail: genly.leon@pucv.cl, E-mail: anpaliat@phys.uoa.gr [Instituto de Ciencias Físicas y Matemáticas, Universidad Austral de Chile, Valdivia (Chile)

    2016-11-01

    We investigate Kantowski-Sachs models in Einstein-æ ther theory with a perfect fluid source using the singularity analysis to prove the integrability of the field equations and dynamical system tools to study the evolution. We find an inflationary source at early times, and an inflationary sink at late times, for a wide region in the parameter space. The results by A.A. Coley, G. Leon, P. Sandin and J. Latta ( JCAP 12 (2015) 010), are then re-obtained as particular cases. Additionally, we select other values for the non-GR parameters which are consistent with current constraints, getting a very rich phenomenology. In particular, we find solutions with infinite shear, zero curvature, and infinite matter energy density in comparison with the Hubble scalar. We also have stiff-like future attractors, anisotropic late-time attractors, or both, in some special cases. Such results are developed analytically, and then verified by numerics. Finally, the physical interpretation of the new critical points is discussed.

  14. Zero electrical resistance of perfect conductor and diamagnet

    International Nuclear Information System (INIS)

    Palaspagar, R.S.

    2012-01-01

    Intense research has taken place to discover new superconductors, to understand the physics that underlies the properties of superconductors, and to develop new applications for these materials. The fascinating phenomenon of superconductivity and its potential applications have attracted the attention of scientists, engineers and businessmen. In this paper we will discuss about the brief history of superconductors. And we will discuss also phenomenons of superconductors and the two different types of superconductor that exist today. We can say that superconductor exhibits infinite conductivity. A bulk specimen of metal in the superconducting state exhibits perfect diamagnetism, with the magnetic induction B=0 named as Meissner effect. It would have been very difficult to have arrived at the theory of superconductivity by purely deductive reasoning from the basic equations of quantum mechanics. A successful quantum theory of superconductivity has provided the basic for subsequent work and the importance of the phase of the superconducting wave function. If we could make a material that was superconducting at room temperature then our computers would work faster because they would allow electric currents to flow more easily. That would mean electric appliances in our homes and offices would waste much less power. We could also make 'Maglev' (magnetic levitation) trains that would float on rails using linear motors and get us around with a fraction of the power used by current locomotives. (author)

  15. Broadband Reflectionless Metasheets: Frequency-Selective Transmission and Perfect Absorption

    Directory of Open Access Journals (Sweden)

    V. S. Asadchy

    2015-07-01

    Full Text Available Energy of propagating electromagnetic waves can be fully absorbed in a thin lossy layer, but only in a narrow frequency band, as follows from the causality principle. On the other hand, it appears that there are no fundamental limitations on broadband matching of thin resonant absorbing layers. However, known thin absorbers produce significant reflections outside of the resonant absorption band. In this paper, we explore possibilities to realize a thin absorbing layer that produces no reflected waves in a very wide frequency range, while the transmission coefficient has a narrow peak of full absorption. Here we show, both theoretically and experimentally, that a thin resonant absorber, invisible in reflection in a very wide frequency range, can be realized if one and the same resonant mode of the absorbing array unit cells is utilized to create both electric and magnetic responses. We test this concept using chiral particles in each unit cell, arranged in a periodic planar racemic array, utilizing chirality coupling in each unit cell but compensating the field coupling at the macroscopic level. We prove that the concept and the proposed realization approach also can be used to create nonreflecting layers for full control of transmitted fields. Our results can have a broad range of potential applications over the entire electromagnetic spectrum including, for example, perfect ultracompact wave filters and selective multifrequency sensors.

  16. Perfect zircon for rock dating no fairy tale

    International Nuclear Information System (INIS)

    Anon

    2000-01-01

    The scheme used to date rocks is based on the radioactive decay of uranium. Minute traces of uranium locked inside the zircon crystals have been decaying over aeons, producing lead. Scientists know that the decay occurs at a fixed rate and how quickly it happens. By measuring the relative amounts of uranium and lead encased in the crystals, scientists can determine how old the rock is. But sometimes lead is lost from zircon crystals via processes such as weathering (if the rocks were exposed on the surface) or deformation and metamorphism (if the rocks had crystallised deep in the earth and been subjected to high temperatures and pressure). Hence the special nature of the Temora rocks- a 417 million years old zirconium-containing rock which have been partially exposed in recent times in a remote paddock in NSW, Australia. SHRIMP dating was used for initial tests on the Temora rocks. Then, in December last year, the sample was sent to the world-recognised authority, Canada's Royal Ontario Museum, for independent analysis and dating via chemical decomposition. The museum confirmed the near perfect quality of the zircon and its age

  17. THE PERFECT ONLINE COURSE: Best Practices for Designing and Teaching

    Directory of Open Access Journals (Sweden)

    Reviewed by Cengiz Hakan AYDIN

    2010-07-01

    Full Text Available The growth of online learning all over the world arise new challenges. One of the major challenges is the issue of quality. What should an online course look like? What kinds of instructional strategies should be provided? To what extent various kinds of interactions must be required? What are the effective learning activities? For what functions should different technologies be used? How can learning be assessed? And similar and more questions have yet no standardized answers although they have been around since early implementations of online learning. Each provider uses different standards developed by either themselves or some institutions or some researchers. Sloan-C: Pillars of Quality, Robley and Wince’s Rubric for Quality Interactions, Concord Model, Schrum’s Qualities of Successful Students, Quality Matters, and E-excellence: Quality Manual for E-learning in Higher Education are among many of these standards.The book, entitled as The Perfect Online Course: Best Practices for Designing and Teaching is also trying to establish a list of standards about how to design and implement an effective online course.The main goal of the book is to create a framework of quality educational guidelines that can be used to offer “perfect” online course.

  18. Perfect imaging of a point charge in the quasistatic regime

    Science.gov (United States)

    Bergman, David J.

    2014-01-01

    An exact calculation of the local electric potential field ψ (r) in the quasistatic limit is described for the case of a point electric charge q in a two-constituent composite medium. In the case of an ɛ2, ɛ1, ɛ2 three-parallel-slab microstructure, where q is in the top ɛ2 layer and both ɛ2 layers are infinitely thick while the ɛ1 layer has a finite thickness L1, a perfect imaging of the point charge is expected if ɛ1=-ɛ2 is real [J. B. Pendry, Phys. Rev. Lett. 85, 3966 (2000), 10.1103/PhysRevLett.85.3966; R. J. Blaikie and D. O. S. Melville, J. Opt. A 7, S176 (2005), 10.1088/1464-4258/7/2/023; U. Leonhardt, New J. Phys. 11, 093040 (2009), 10.1088/1367-2630/11/9/093040]. Among our results we find that an infinite resolution image of the point charge q is only achievable if the actual charge is situated at a distance that is between L1/2 and L1 away from the ɛ1 layer.

  19. Exact EGB models for spherical static perfect fluids

    Energy Technology Data Exchange (ETDEWEB)

    Hansraj, Sudan; Chilambwe, Brian; Maharaj, Sunil D. [University of KwaZulu-Natal, Astrophysics and Cosmology Research Unit, School of Mathematics, Statistics and Computer Science, Private Bag 54001, Durban (South Africa)

    2015-06-15

    We obtain a new exact solution to the field equations for a 5-dimensional spherically symmetric static distribution in the Einstein-Gauss-Bonnet modified theory of gravity. By using a transformation, the study is reduced to the analysis of a single second order nonlinear differential equation. In general the condition of pressure isotropy produces a first order differential equation which is an Abel equation of the second kind. An exact solution is found. The solution is examined for physical admissibility. In particular a set of constants is found which ensures that a pressure-free hypersurface exists which defines the boundary of the distribution. Additionally the isotropic pressure and the energy density are shown to be positive within the radius of the sphere. The adiabatic sound-speed criterion is also satisfied within the fluid ensuring a subluminal sound speed. Furthermore, the weak, strong and dominant conditions hold throughout the distribution. On setting the Gauss-Bonnet coupling to zero, an exact solution for 5-dimensional perfect fluids in the standard Einstein theory is obtained. Plots of the dynamical quantities for the Gauss-Bonnet and the Einstein case reveal that the pressure is unaffected, while the energy density increases under the influence of the Gauss-Bonnet term. (orig.)

  20. Near-perfect broadband absorption from hyperbolic metamaterial nanoparticles

    Science.gov (United States)

    Riley, Conor T.; Smalley, Joseph S. T.; Brodie, Jeffrey R. J.; Fainman, Yeshaiahu; Sirbuly, Donald J.; Liu, Zhaowei

    2017-02-01

    Broadband absorbers are essential components of many light detection, energy harvesting, and camouflage schemes. Current designs are either bulky or use planar films that cause problems in cracking and delamination during flexing or heating. In addition, transferring planar materials to flexible, thin, or low-cost substrates poses a significant challenge. On the other hand, particle-based materials are highly flexible and can be transferred and assembled onto a more desirable substrate but have not shown high performance as an absorber in a standalone system. Here, we introduce a class of particle absorbers called transferable hyperbolic metamaterial particles (THMMP) that display selective, omnidirectional, tunable, broadband absorption when closely packed. This is demonstrated with vertically aligned hyperbolic nanotube (HNT) arrays composed of alternating layers of aluminum-doped zinc oxide and zinc oxide. The broadband absorption measures >87% from 1,200 nm to over 2,200 nm with a maximum absorption of 98.1% at 1,550 nm and remains large for high angles. Furthermore, we show the advantages of particle-based absorbers by transferring the HNTs to a polymer substrate that shows excellent mechanical flexibility and visible transparency while maintaining near-perfect absorption in the telecommunications region. In addition, other material systems and geometries are proposed for a wider range of applications.

  1. Shear-free perfect fluids with zero magnetic Weyl tensor

    International Nuclear Information System (INIS)

    Collins, C.B.

    1984-01-01

    Rotating, shear-free general-relativistic perfect fluids are investigated. It is first shown that, if the fluid pressure, p, and energy density, μ, are related by a barotropic equation of state p = p( μ) satifying μ+pnot =0, and if the magnetic part of the Weyl tensor (with respect to the fluid flow) vanishes, then the fluid's volume expansion is zero. The class of all such fluids is subsequently characterized. Further analysis of the solutions shows that, in general, the space-times may be regarded as being locally stationary and axisymmetric (they admit a two-dimensional Abelian isometry group with timelike orbits, which is in fact orthogonally transistive), although various specializations can occur, with the ''most special'' case being the well-known Goedel model, which is space-time homogeneous (it admits a five-dimensional isometry group acting multiply transitively on the space-time). all solutions are of Petrov type D. The fact that there are any solutions in the class at all means that a theorem appearing in the literature is invalid, and the existence of some special solutions in which the fluid's vorticity vector is orthogonal to the acceleration reveals the incompleteness of a previous study of a class of space-times, in which there are Killing vectors parallel to the fluid four-velocity and to the vorticity vector

  2. Improving The Perfect Storm: Overcoming Barriers To Climate Literacy

    Science.gov (United States)

    Tillinger, D.

    2015-12-01

    Students and scientists are trained to speak different languages. Climate science, and the geosciences more broadly, are strictly classroom topics, not subjects appropriate for casual conversation, social media, or creative projects. When students are aware of climate change through the mainstream media, it is nearly always in a political or technological context rather than a scientific one. However, given the opportunity, students are perfectly capable of not only understanding the science behind climate change, but communicating it to their peers. At the American Museum of Natural History, a group of underprivileged high school students visited Nature's Fury: The Science of Natural Disasters to learn about volcanoes, earthquakes, and climate change impacts. They were then able to write pitches and develop trailers for scientifically accurate, but still compelling, disaster movies. Arts in Parts, a creative outreach group formed as a response to Hurricane Sandy, facilitated a workshop in which younger children made mobiles from beach debris they collected while learning about the the threat of sea level rise locally and globally. Participants in an undergraduate natural disasters class wrote guides to understanding climate change that remained factual while showing great creativity and reflecting the personality of each student. Art, humor, and popular culture are the languages that society chooses to use; scientific literacy might benefit from their inclusion.

  3. Building the perfect parasite: cell division in apicomplexa.

    Directory of Open Access Journals (Sweden)

    Boris Striepen

    2007-06-01

    Full Text Available Apicomplexans are pathogens responsible for malaria, toxoplasmosis, and crytposporidiosis in humans, and a wide range of livestock diseases. These unicellular eukaryotes are stealthy invaders, sheltering from the immune response in the cells of their hosts, while at the same time tapping into these cells as source of nutrients. The complexity and beauty of the structures formed during their intracellular development have made apicomplexans the darling of electron microscopists. Dramatic technological progress over the last decade has transformed apicomplexans into respectable genetic model organisms. Extensive genomic resources are now available for many apicomplexan species. At the same time, parasite transfection has enabled researchers to test the function of specific genes through reverse and forward genetic approaches with increasing sophistication. Transfection also introduced the use of fluorescent reporters, opening the field to dynamic real time microscopic observation. Parasite cell biologists have used these tools to take a fresh look at a classic problem: how do apicomplexans build the perfect invasion machine, the zoite, and how is this process fine-tuned to fit the specific niche of each pathogen in this ancient and very diverse group? This work has unearthed a treasure trove of novel structures and mechanisms that are the focus of this review.

  4. Antiviral Activity and Resistance Analysis of NS3/4A Protease Inhibitor Grazoprevir and NS5A Inhibitor Elbasvir in Hepatitis C Virus GT4 Replicons.

    Science.gov (United States)

    Asante-Appiah, Ernest; Curry, Stephanie; McMonagle, Patricia; Ingravallo, Paul; Chase, Robert; Nickle, David; Qiu, Ping; Howe, Anita; Lahser, Frederick C

    2017-07-01

    Although genotype 4 (GT4)-infected patients represent a minor overall percentage of the global hepatitis C virus (HCV)-infected population, the high prevalence of the genotype in specific geographic regions coupled with substantial sequence diversity makes it an important genotype to study for antiviral drug discovery and development. We evaluated two direct-acting antiviral agents-grazoprevir, an HCV NS3/4A protease inhibitor, and elbasvir, an HCV NS5A inhibitor-in GT4 replicons prior to clinical studies in this genotype. Following a bioinformatics analysis of available GT4 sequences, a set of replicons bearing representative GT4 clinical isolates was generated. For grazoprevir, the 50% effective concentration (EC 50 ) against the replicon bearing the reference GT4a (ED43) NS3 protease and NS4A was 0.7 nM. The median EC 50 for grazoprevir against chimeric replicons encoding NS3/4A sequences from GT4 clinical isolates was 0.2 nM (range, 0.11 to 0.33 nM; n = 5). The difficulty in establishing replicons bearing NS3/4A resistance-associated substitutions was substantially overcome with the identification of a G162R adaptive substitution in NS3. Single NS3 substitutions D168A/V identified from de novo resistance selection studies reduced grazoprevir antiviral activity by 137- and 47-fold, respectively, in the background of the G162R replicon. For elbasvir, the EC 50 against the replicon bearing the reference full-length GT4a (ED43) NS5A gene was 0.0002 nM. The median EC 50 for elbasvir against chimeric replicons bearing clinical isolates from GT4 was 0.0007 nM (range, 0.0002 to 34 nM; n = 14). De novo resistance selection studies in GT4 demonstrated a high propensity to suppress the emergence of amino acid substitutions that confer high-potency reductions to elbasvir. Phenotypic characterization of the NS5A amino acid substitutions identified (L30F, L30S, M31V, and Y93H) indicated that they conferred 15-, 4-, 2.5-, and 7.5-fold potency losses, respectively, to elbasvir

  5. PERFECTED enhanced recovery (PERFECT-ER) care versus standard acute care for patients admitted to acute settings with hip fracture identified as experiencing confusion: study protocol for a feasibility cluster randomized controlled trial.

    Science.gov (United States)

    Hammond, Simon P; Cross, Jane L; Shepstone, Lee; Backhouse, Tamara; Henderson, Catherine; Poland, Fiona; Sims, Erika; MacLullich, Alasdair; Penhale, Bridget; Howard, Robert; Lambert, Nigel; Varley, Anna; Smith, Toby O; Sahota, Opinder; Donell, Simon; Patel, Martyn; Ballard, Clive; Young, John; Knapp, Martin; Jackson, Stephen; Waring, Justin; Leavey, Nick; Howard, Gregory; Fox, Chris

    2017-12-04

    Health and social care provision for an ageing population is a global priority. Provision for those with dementia and hip fracture has specific and growing importance. Older people who break their hip are recognised as exceptionally vulnerable to experiencing confusion (including but not exclusively, dementia and/or delirium and/or cognitive impairment(s)) before, during or after acute admissions. Older people experiencing hip fracture and confusion risk serious complications, linked to delayed recovery and higher mortality post-operatively. Specific care pathways acknowledging the differences in patient presentation and care needs are proposed to improve clinical and process outcomes. This protocol describes a multi-centre, feasibility, cluster-randomised, controlled trial (CRCT) to be undertaken across ten National Health Service hospital trusts in the UK. The trial will explore the feasibility of undertaking a CRCT comparing the multicomponent PERFECTED enhanced recovery intervention (PERFECT-ER), which acknowledges the differences in care needs of confused older patients experiencing hip fracture, with standard care. The trial will also have an integrated process evaluation to explore how PERFECT-ER is implemented and interacts with the local context. The study will recruit 400 hip fracture patients identified as experiencing confusion and will also recruit "suitable informants" (individuals in regular contact with participants who will complete proxy measures). We will also recruit NHS professionals for the process evaluation. This mixed methods design will produce data to inform a definitive evaluation of the intervention via a large-scale pragmatic randomised controlled trial (RCT). The trial will provide a preliminary estimate of potential efficacy of PERFECT-ER versus standard care; assess service delivery variation, inform primary and secondary outcome selection, generate estimates of recruitment and retention rates, data collection difficulties, and

  6. Coordination in continuously repeated games

    NARCIS (Netherlands)

    Weeren, A.J.T.M.; Schumacher, J.M.; Engwerda, J.C.

    1995-01-01

    In this paper we propose a model to describe the effectiveness of coordination in a continuously repeated two-player game. We study how the choice of a decision rule by a coordinator affects the strategic behavior of the players, resulting in more or less cooperation. Our model requires the analysis

  7. Repeated checking causes memory distrust

    NARCIS (Netherlands)

    van den Hout, M.; Kindt, M.

    2003-01-01

    This paper attempts to explain why in obsessive-compulsive disorder (OCD) checkers distrust in memory persists despite extensive checking. It is argued that: (1) repeated checking increases familiarity with the issues checked; (2) increased familiarity promotes conceptual processing which inhibits

  8. A perfect storm? Welfare, care, gender and generations in Uruguay.

    Science.gov (United States)

    Filgueira, Fernando; Gutiérrez, Magdalena; Papadópulos, Jorge

    2011-01-01

    This article claims that welfare states modelled on a contributory basis and with a system of entitlements that assumes stable two-parent families, a traditional breadwinner model, full formal employment and a relatively young age structure are profoundly flawed in the context of present-day challenges. While this is true for affluent countries modelled on the Bismarckian type of welfare system, the costs of the status quo are even more devastating in middle-income economies with high levels of inequality. A gendered approach to welfare reform that introduces the political economy and the economy of care and unpaid work is becoming critical to confront what may very well become a perfect storm for the welfare of these nations and their peoples. Through an in-depth study of the Uruguayan case, the authors show how the decoupling of risk and protection has torn asunder the efficacy of welfare devices in the country. An ageing society that has seen a radical transformation of its family and labour market landscapes, Uruguay maintained during the 1980s and 1990s a welfare state that was essentially contributory, elderly and male-oriented, and centred on cash entitlements. This contributed to the infantilization of poverty, increased the vulnerability of women and exacerbated fiscal stress for the system as a whole. Furthermore, because of high levels of income and asset inequality, the redistribution of risk between upper- and lower-income groups presented a deeply regressive pattern. The political economy of care and welfare has begun to change in the last decade or so, bringing about mild reforms in the right direction; but these might prove to be too little and too late.

  9. Carrier mobility and crystal perfection of tetracene thin film FET

    International Nuclear Information System (INIS)

    Moriguchi, N.; Nishikawa, T.; Anezaki, T.; Unno, A.; Tachibana, M.; Kojima, K.

    2006-01-01

    It is well-known that the carrier mobility of an organic field effect semiconductor (FET) depended on the crystal quality and/or the crystal perfection of the organic thin films [T.W. Kelly, D.V. Muyres, P.F. Baude, T.P. Smith, T.D. Jones, Mater. Res. Soc. Symp. Proc. 771 (2003) L6.5.1; D.J. Gundlach, J.A. Nichols, L. Zhou, T.N. Jackson, Appl. Phys. Lett. 80 (2002) 2925; H.K. Lauk, M. Halik, U. Zschieschang, G. Schmid, W. Radlik, J. Appl. Phys. 92 (2002) 5259; M. Shtein, J. Mapel, J.B. Benziger, S.R. Forrest, Appl. Phys. Lett. 81 (2002) 268; D. Knipp, R.A. Street, A.R. Volkel, Appl. Phys. Lett. 82 (2003) 3907; R. Ruiz, A.C. Mayer, G.G. Malliaras, Appl. Phys. Lett. 85 (2004) 4926; R.W.I. de Boer, M.E. Gershenson, A.F. Morpurgo, V. Podzorov, Phys. Stat. Sol. A 201 (2004) 1031]. To improve the crystal quality of the thin film many efforts were made. One of the important improvements was the surface treatment of the substrate. The tetracene thin film FET (top contact structure) was fabricated using the substrate, which was coated by a spin-coating method with a 0.1% poly α-methylstyrene (AMS) solution. The crystal quality was improved by this treatment so that the carrier mobility was higher than that of non-treatment. The maximum mobility of the AMS-treated sample was obtained to be 0.12 cm 2 /V s

  10. WD40-repeat proteins in plant cell wall formation: current evidence and research prospects

    Directory of Open Access Journals (Sweden)

    Gea eGuerriero

    2015-12-01

    Full Text Available The metabolic complexity of living organisms relies on supramolecular protein structures which ensure vital processes, such as signal transduction, transcription, translation and cell wall synthesis. In eukaryotes WD40-repeat (WDR proteins often function as molecular hubs mediating supramolecular interactions. WDR proteins may display a variety of interacting partners and participate in the assembly of complexes involved in distinct cellular functions. In plants, the formation of lignocellulosic biomass involves extensive synthesis of cell wall polysaccharides, a process that requires the assembly of large transmembrane enzyme complexes, intensive vesicle trafficking, interactions with the cytoskeleton, and coordinated gene expression. Because of their function as supramolecular hubs, WDR proteins could participate in each or any of these steps, although to date only few WDR proteins have been linked to the cell wall by experimental evidence. Nevertheless, several potential cell wall-related WDR proteins were recently identified using in silico aproaches, such as analyses of co-expression, interactome and conserved gene neighbourhood. Notably, some WDR genes are frequently genomic neighbours of genes coding for GT2-family polysaccharide synthases in eukaryotes, and this WDR-GT2 collinear microsynteny is detected in diverse taxa. In angiosperms, two WDR genes are collinear to cellulose synthase genes, CESAs, whereas in ascomycetous fungi several WDR genes are adjacent to chitin synthase genes, chs. In this Perspective we summarize and discuss experimental and in silico studies on the possible involvement of WDR proteins in plant cell wall formation. The prospects of biotechnological engineering for enhanced biomass production are discussed.

  11. On the perfectness of C^{∞,s}-diffeomorphism groups on a foliated manifold

    OpenAIRE

    Jacek Lech

    2008-01-01

    The notion of \\(C^{r,s}\\) and \\(C^{\\infty,s}\\)-diffeomorphisms is introduced. It is shown that the identity component of the group of leaf preserving \\(C^{\\infty,s}\\)-diffeomorphisms with compact supports is perfect. This result is a modification of the Mather and Epstein perfectness theorem.

  12. 10 CFR 611.108 - Perfection of liens and preservation of collateral.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Perfection of liens and preservation of collateral. 611... of collateral. (a) The Agreement and other documents related thereto shall provide that: (1) DOE and... necessary to perfect and maintain liens, as applicable, on assets which are pledged as collateral for the...

  13. Tunable THz perfect absorber with two absorption peaks based on graphene microribbons

    DEFF Research Database (Denmark)

    Gu, Mingyue; Xiao, Binggang; Xiao, Sanshui

    2018-01-01

    Perfect absorption is characterised by the complete suppression of incident and reflected electromagnetic wave, and complete dissipation of the incident energy. A tunable perfect terahertz (THz) absorber with two absorption peaks based on graphene is presented. The proposed structure consists of ...

  14. The Perfect Eye A Novel Model for Teaching the Theory of Refraction.

    Science.gov (United States)

    Kurtz, Daniel

    1999-01-01

    The Perfect Eye model simplifies solutions to a wide variety of optometry instructional problems by facilitating student understanding of the interaction among lenses, objects, accommodation, and ametropia. The model is based on the premise that inside every eye is a perfect (emmetropic) eye, and that the physiological eye is a combination of the…

  15. AN FDTD ALGORITHM WITH PERFECTLY MATCHED LAYERS FOR CONDUCTIVE MEDIA. (R825225)

    Science.gov (United States)

    We extend Berenger's perfectly matched layers (PML) to conductive media. A finite-difference-time-domain (FDTD) algorithm with PML as an absorbing boundary condition is developed for solutions of Maxwell's equations in inhomogeneous, conductive media. For a perfectly matched laye...

  16. Making perfect life : bio-engineering (in) the 21st century : interim study

    NARCIS (Netherlands)

    Est, van R.; Keulen, van I.; Geesink, I.; Schuiff, M.

    2010-01-01

    Reportnumber: PE 438.829; This document is the result of the preparatory phase of the STOA-project "Making perfect life", that defined the project focus. This resulted in the study document Making Perfect Life: Bio-engineering (in) the 21st century. A project plan for the next two phases was

  17. On the Galois cohomology of unipotent groups and extensions of non-perfect fields

    International Nuclear Information System (INIS)

    Nguyen Duy Tan; Nguyen Quoc Thang

    2006-12-01

    In this note we discuss, in the case of unipotent groups over non-perfect fields, an analog of Serre's conjectures for unipotent algebraic group schemes, which relates properties of Galois (or flat) cohomology of unipotent group schemes to finite extensions of non-perfect fields, and Russel's defining equations of one-dimensional unipotent groups. (author)

  18. Hit by a Perfect Storm? Art & Design in the National Student Survey

    Science.gov (United States)

    Yorke, Mantz; Orr, Susan; Blair, Bernadette

    2014-01-01

    There has long been the suspicion amongst staff in Art & Design that the ratings given to their subject disciplines in the UK's National Student Survey are adversely affected by a combination of circumstances--a "perfect storm". The "perfect storm" proposition is tested by comparing ratings for Art & Design with those…

  19. Tumor Necrosis Factor (TNF -308G>A, Nitric Oxide Synthase 3 (NOS3 +894G>T Polymorphisms and Migraine Risk: A Meta-Analysis.

    Directory of Open Access Journals (Sweden)

    Min Chen

    Full Text Available Conflicting data have been reported on the association between tumor necrosis factor (TNF -308G>A and nitric oxide synthase 3 (NOS3 +894G>T polymorphisms and migraine. We performed a meta-analysis of case-control studies to evaluate whether the TNF -308G>A and NOS3 +894G>T polymorphisms confer genetic susceptibility to migraine.We performed an updated meta-analysis for TNF -308G>A and a meta-analysis for NOS3 +894G>T based on studies published up to July 2014. We calculated study specific odds ratios (OR and 95% confidence intervals (95% CI assuming allele contrast, dominant model, recessive model, and co-dominant model as pooled effect estimates.Eleven studies in 6682 migraineurs and 22591 controls for TNF -308G>A and six studies in 1055 migraineurs and 877 controls for NOS3 +894G>T were included in the analysis. Neither indicated overall associations between gene polymorphisms and migraine risk. Subgroup analyses suggested that the "A" allele of the TNF -308G>A variant increases the risk of migraine among non-Caucasians (dominant model: pooled OR = 1.82; 95% CI 1.15 - 2.87. The risk of migraine with aura (MA was increased among both Caucasians and non-Caucasians. Subgroup analyses suggested that the "T" allele of the NOS3 +894G>T variant increases the risk of migraine among non-Caucasians (co-dominant model: pooled OR = 2.10; 95% CI 1.14 - 3.88.Our findings appear to support the hypothesis that the TNF -308G>A polymorphism may act as a genetic susceptibility factor for migraine among non-Caucasians and that the NOS3 +894G>T polymorphism may modulate the risk of migraine among non-Caucasians.

  20. GT-MHR COMMERCIALZATION STUDY. TECHNICAL PROGRESS AND COST MANAGEMENT REPORT FOR THE PERIOD MAY 1 THROUGH MAY 31, 2003

    International Nuclear Information System (INIS)

    SHENOY, A.S.

    2003-01-01

    A271 GT-MHR COMMERCIALZATION STUDY TECHNICAL PROGRESS AND COST MANAGEMENT REPORT FOR THE PERIOD MAY 1 THROUGH MAY 31, 2003. Petten advised GA the start of the HFR-EU2 irradiation is being delayed until late July 2004. HFR-EU1 (pebble fuel) is also delayed until February/March 2004. The reason for the delays was implementation of new financial regulations at Petten that delayed the contracts for capsule fabrication. Review of the MHR-2 Fuel Product Specification was completed. Revision of the specification to incorporate the review results is in progress. Detailed test matrices have been drafted for capsule irradiation tests and for post-irradiation heating tests proposed for development and qualification of advanced coated-particle fuels capable of meeting anticipated VHTR fuel performance requirements

  1. GT-MHR COMMERCIALZATION STUDY. TECHNICAL PROGRESS AND COST MANAGEMENT REPORT FOR THE PERIOD JUNE 1 THROUGH JUNE 30, 2003

    International Nuclear Information System (INIS)

    SHENOY, A.S.

    2003-01-01

    A271 GT-MHR COMMERCIALZATION STUDY TECHNICAL PROGRESS AND COST MANAGEMENT REPORT FOR THE PERIOD JUNE 1 THROUGH JUNE 30, 2003. Petten was provided with irradiation dimensional change data for both fuel compacts and H-451 graphite for design of the graphite sleeves that hold the fuel compacts to be irradiated in HFR-EU2. The Fuel Sample Product Specification for the Fuel Performance Irradiation Test Capsule MHR-2 was completed and approved. A Work Breakdown Structure was prepared for the development and qualification of advanced coated-particle fuels capable of meeting anticipated fuel performance requirements and work was initiated on preparation of schedules and a cost estimates for the test matrices

  2. Can mt2 much-gt mb2 arise from small corrections in four-family models

    International Nuclear Information System (INIS)

    Mendel, R.R.; Margolis, B.; Therrien, E.; Valin, P.

    1989-01-01

    This paper proposes a general dynamical scheme capable of explaining naturally the main properties of the observed spectrum, namely the strong inter-family mass hierarchies and the mixing pattern. The authors illustrate these properties in the three-family case with a simple toy model. There is an indication that large values of m t may be required in order to obtain |V by |much-lt|V bc ; the fact the m 2 much-gt m 2 could be due to small corrections in a four-family model where m' ∼ m'. The authors point out possible natural explanations for the small mass of the e, μ and τ neutrinos in the three and four family cases

  3. Effect of heat treatment on impact resistance of AU5GT and AS7G06 aluminum alloys

    Energy Technology Data Exchange (ETDEWEB)

    Muzamil, Muhammad; Akhtar, Maaz; Samiuddin, Muhammad; Mehdi, Murtuza [NED University of Engineering and Technology, Karachi (Pakistan)

    2016-10-15

    Impact strength is one of the major mechanical properties that a material should possess in order to absorb sudden changes in the load intensity. The objective of current study is to compare the impact strength of two material (AU5GT and AS7G06), which are used in different structural applications. Almost no work is available which compares the impact strength of selected grade alloys along with different heat treatment cycles. Specimens are heat treated first as per designed cycles, later impact testing is performed. Charpy impact test is conducted in accordance with ASTM E23-12 standard method on three samples with and without heat treatment for each cycle. Solutionizing on samples is done at constant time and temperature to achieve homogenization. Later, aging is conducted at different temperatures ranging from 100-200°C (different intervals) at constant time to find the effect of precipitation hardness that actually increases the strength. Sample hardness is determined using Vickers micro hardness testing machine for each heat treatment cycle. Charpy test results provided the impact energy that is used to determine the strength before fracture. Heat treated samples have showed increase in impact strength for AS7G06 aluminum alloy while AU5GT shows very little change. This is because of growing the precipitation with respect to temperature, which resulted in more hard regions across grains. Hardness also shows an increasing relationship, as expected. Fracture surfaces are analyzed on stereo microscopy and Scanning electron microscopy (SEM) to find the final mode of fracture, that is brittle, ductile or transitional (combination of both brittle and ductile)

  4. Chronic exposure to KATP channel openers results in attenuated glucose sensing in hypothalamic GT1-7 neurons.

    Science.gov (United States)

    Haythorne, Elizabeth; Hamilton, D Lee; Findlay, John A; Beall, Craig; McCrimmon, Rory J; Ashford, Michael L J

    2016-12-01

    Individuals with Type 1 diabetes (T1D) are often exposed to recurrent episodes of hypoglycaemia. This reduces hormonal and behavioural responses that normally counteract low glucose in order to maintain glucose homeostasis, with altered responsiveness of glucose sensing hypothalamic neurons implicated. Although the molecular mechanisms are unknown, pharmacological studies implicate hypothalamic ATP-sensitive potassium channel (K ATP ) activity, with K ATP openers (KCOs) amplifying, through cell hyperpolarization, the response to hypoglycaemia. Although initial findings, using acute hypothalamic KCO delivery, in rats were promising, chronic exposure to the KCO NN414 worsened the responses to subsequent hypoglycaemic challenge. To investigate this further we used GT1-7 cells to explore how NN414 affected glucose-sensing behaviour, the metabolic response of cells to hypoglycaemia and K ATP activity. GT1-7 cells exposed to 3 or 24 h NN414 exhibited an attenuated hyperpolarization to subsequent hypoglycaemic challenge or NN414, which correlated with diminished K ATP activity. The reduced sensitivity to hypoglycaemia was apparent 24 h after NN414 removal, even though intrinsic K ATP activity recovered. The NN414-modified glucose responsiveness was not associated with adaptations in glucose uptake, metabolism or oxidation. K ATP inactivation by NN414 was prevented by the concurrent presence of tolbutamide, which maintains K ATP closure. Single channel recordings indicate that NN414 alters K ATP intrinsic gating inducing a stable closed or inactivated state. These data indicate that exposure of hypothalamic glucose sensing cells to chronic NN414 drives a sustained conformational change to K ATP , probably by binding to SUR1, that results in loss of channel sensitivity to intrinsic metabolic factors such as MgADP and small molecule agonists. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  5. Online learning in repeated auctions

    OpenAIRE

    Weed, Jonathan; Perchet, Vianney; Rigollet, Philippe

    2015-01-01

    Motivated by online advertising auctions, we consider repeated Vickrey auctions where goods of unknown value are sold sequentially and bidders only learn (potentially noisy) information about a good's value once it is purchased. We adopt an online learning approach with bandit feedback to model this problem and derive bidding strategies for two models: stochastic and adversarial. In the stochastic model, the observed values of the goods are random variables centered around the true value of t...

  6. A repeating fast radio burst.

    Science.gov (United States)

    Spitler, L G; Scholz, P; Hessels, J W T; Bogdanov, S; Brazier, A; Camilo, F; Chatterjee, S; Cordes, J M; Crawford, F; Deneva, J; Ferdman, R D; Freire, P C C; Kaspi, V M; Lazarus, P; Lynch, R; Madsen, E C; McLaughlin, M A; Patel, C; Ransom, S M; Seymour, A; Stairs, I H; Stappers, B W; van Leeuwen, J; Zhu, W W

    2016-03-10

    Fast radio bursts are millisecond-duration astronomical radio pulses of unknown physical origin that appear to come from extragalactic distances. Previous follow-up observations have failed to find additional bursts at the same dispersion measure (that is, the integrated column density of free electrons between source and telescope) and sky position as the original detections. The apparent non-repeating nature of these bursts has led to the suggestion that they originate in cataclysmic events. Here we report observations of ten additional bursts from the direction of the fast radio burst FRB 121102. These bursts have dispersion measures and sky positions consistent with the original burst. This unambiguously identifies FRB 121102 as repeating and demonstrates that its source survives the energetic events that cause the bursts. Additionally, the bursts from FRB 121102 show a wide range of spectral shapes that appear to be predominantly intrinsic to the source and which vary on timescales of minutes or less. Although there may be multiple physical origins for the population of fast radio bursts, these repeat bursts with high dispersion measure and variable spectra specifically seen from the direction of FRB 121102 support an origin in a young, highly magnetized, extragalactic neutron star.

  7. A Reference Section through the Lower Fast-spreading Oceanic Crust in the Wadi Gideah (Sumail ophiolite, Sultanate Oman): Drill Sites GT1A and GT2A within the ICDP Oman Drilling Project

    Science.gov (United States)

    Mueller, S.; Koepke, J.; Garbe-Schoenberg, C. D.; Müller, T.; Mock, D.; Strauss, H.; Schuth, S.; Ildefonse, B.

    2017-12-01

    In the absence of a complete profile through fast-spreading oceanic crust in modern oceans, we established a reference profile through the whole paleocrust of the Sumail Ophiolite (Oman), which is regarded as the best analogue for fast-spreading oceanic crust on land. For establishing a coherent data set, we sampled the Wadi Gideah in the Wadi-Tayin massif from the mantle section up to the pillow basalts and performed different analytical and structural investigations on the same suite of samples (pool sample concept). The whole sample set contains about 400 samples focusing on both primary magmatic rocks and hydrothermal fault zones to characterize initial formation processes and cooling of the crust. The Wadi Gideah hosts the sites GT1A (lower crust) and GT2A (foliated / layered gabbro transition) where 400 m long cores have been drilled in the frame of the ICDP Oman Drilling Project (OmanDP). Thus, the Wadi Gideah crustal transect is well-suited for providing a reference frame for these two drill cores. Major and trace element data on minerals and rocks reveal in-situ crystallization in the deep crust, thus strongly supporting a hybrid accretion model that is characterized by sheeted sill intrusion in the lower part of the plutonic crust and gabbro glacier features in the upper section. This hybrid model is also supported by results on crystallographic preferred orientations (CPO) of the minerals within the gabbros, which call for distinct formation mechanisms in the upper and lower gabbro sections. A requirement for our hybrid model is significant hydrothermal cooling in the lower crust for the consumption of the latent heat of crystallization. This was facilitated by channelled hydrothermal flow zones, preserved today in faulted zones of extensively altered gabbro cutting both layered and foliated gabbros. These gabbros show higher Sr87/Sr86 ratios if compared to the background gabbro, the presence of late stage minerals (amphibole, oxides, orthopyroxene

  8. Metabolic Thresholds and Validated Accelerometer Cutoff Points for the Actigraph GT1M in Young Children Based on Measurements of Locomotion and Play Activities

    Science.gov (United States)

    Jimmy, Gerda; Dossegger, Alain; Seiler, Roland; Mader, Urs

    2012-01-01

    The purpose of the current study was to determine metabolic thresholds and subsequent activity intensity cutoff points for the ActiGraph GT1M with various epochs spanning from 5 to 60 sec in young children. Twenty-two children, aged 4 to 9 years, performed 10 different activities including locomotion and play activities. Energy expenditure was…

  9. Rotary nickel-titanium GT and ProTaper files for root canal shaping by novice operators: a radiographic and micro-computed tomography evaluation.

    Science.gov (United States)

    Gekelman, Diana; Ramamurthy, Ramya; Mirfarsi, Sahar; Paqué, Frank; Peters, Ove A

    2009-11-01

    The purpose of this study was to assess canal preparation outcomes in vitro by novice clinicians after standardized teaching sessions. All students received a training session. In experiment 1, twenty canals of mandibular molars were prepared with GT and ProTaper rotaries by 10 students. Standardized radiographs were exposed before and after canal preparation, and canal curvature was measured; canals were assessed for patency and preparation time. In experiment 2, mandibular molars (20 canals) were submitted to microcomputed tomography before and after canal preparation with ProTaper and GT rotaries by 2 dental students. Canals were metrically assessed for changes (volume, surface, cross-sectional shape, transportation) during canal preparation by using software. In experiment 1, canal curvature decreased by 7.6 degrees and 7.8 degrees for GT and ProTaper preparations; there were no broken instruments, and 2 canals lost patency. The time for GT preparation was longer than for ProTaper (29.7 +/- 6.8 vs 19.4 +/- 8.1 minutes, P session.

  10. Nurturing Gifted and Talented Students to Become Future Leaders: The Innovative Curriculum for the Gifted and/or Talented at GT College in Hong Kong

    Science.gov (United States)

    Tam, Raymond Kwok-Wai

    2017-01-01

    In the previous literature on gifted education in Hong Kong, there has been little mention of special schools for gifted and/or talented students in Hong Kong except for GT College, Hong Kong's first college for the gifted. Some notable researchers in gifted education in Hong Kong have described the college briefly with regard to its admission…

  11. Computing a quasi-perfect equilibrium of a two-player game

    DEFF Research Database (Denmark)

    Miltersen, Peter Bro; Sørensen, Troels Bjerre

    2010-01-01

    Refining an algorithm due to Koller, Megiddo and von Stengel, we show how to apply Lemke's algorithm for solving linear complementarity programs to compute a quasi-perfect equilibrium in behavior strategies of a given two-player extensive-form game of perfect recall. A quasi-perfect equilibrium...... of a zero-sum game, we devise variants of the algorithm that rely on linear programming rather than linear complementarity programming and use the simplex algorithm or other algorithms for linear programming rather than Lemke's algorithm. We argue that these latter algorithms are relevant for recent...

  12. Implementation of a perfect metamaterial absorber into multi-functional sensor applications

    Science.gov (United States)

    Akgol, O.; Karaaslan, M.; Unal, E.; Sabah, C.

    2017-05-01

    Perfect metamaterial absorber (MA)-based sensor applications are presented and investigated in the microwave frequency range. It is also experimentally analyzed and tested to verify the behavior of the MA. Suggested perfect MA-based sensor has a simple configuration which introduces flexibility to sense the dielectric properties of a material and the pressure of the medium. The investigated applications include pressure and density sensing. Besides, numerical simulations verify that the suggested sensor achieves good sensing capabilities for both applications. The proposed perfect MA-based sensor variations enable many potential applications in medical or food technologies.

  13. Improving repeatability by improving quality

    Energy Technology Data Exchange (ETDEWEB)

    Ronen, Shuki; Ackers, Mark; Schlumberger, Geco-Prakla; Brink, Mundy

    1998-12-31

    Time lapse (4-D) seismic is a promising tool for reservoir characterization and monitoring. The method is apparently simple: to acquire data repeatedly over the same reservoir, process and interpret the data sets, then changes between the data sets indicate changes in the reservoir. A problem with time lapse seismic data is that reservoirs are a relatively small part of the earth and important reservoir changes may cause very small differences to the time lapse data. The challenge is to acquire and process economical time lapse data such that reservoir changes can be detected above the noise of varying acquisition and environment. 7 refs., 9 figs.

  14. Telomerase Repeated Amplification Protocol (TRAP).

    Science.gov (United States)

    Mender, Ilgen; Shay, Jerry W

    2015-11-20

    Telomeres are found at the end of eukaryotic linear chromosomes, and proteins that bind to telomeres protect DNA from being recognized as double-strand breaks thus preventing end-to-end fusions (Griffith et al. , 1999). However, due to the end replication problem and other factors such as oxidative damage, the limited life span of cultured cells (Hayflick limit) results in progressive shortening of these protective structures (Hayflick and Moorhead, 1961; Olovnikov, 1973). The ribonucleoprotein enzyme complex telomerase-consisting of a protein catalytic component hTERT and a functional RNA component hTR or hTERC - counteracts telomere shortening by adding telomeric repeats to the end of chromosomes in ~90% of primary human tumors and in some transiently proliferating stem-like cells (Shay and Wright, 1996; Shay and Wright, 2001). This results in continuous proliferation of cells which is a hallmark of cancer. Therefore, telomere biology has a central role in aging, cancer progression/metastasis as well as targeted cancer therapies. There are commonly used methods in telomere biology such as Telomere Restriction Fragment (TRF) (Mender and Shay, 2015b), Telomere Repeat Amplification Protocol (TRAP) and Telomere dysfunction Induced Foci (TIF) analysis (Mender and Shay, 2015a). In this detailed protocol we describe Telomere Repeat Amplification Protocol (TRAP). The TRAP assay is a popular method to determine telomerase activity in mammalian cells and tissue samples (Kim et al. , 1994). The TRAP assay includes three steps: extension, amplification, and detection of telomerase products. In the extension step, telomeric repeats are added to the telomerase substrate (which is actually a non telomeric oligonucleotide, TS) by telomerase. In the amplification step, the extension products are amplified by the polymerase chain reaction (PCR) using specific primers (TS upstream primer and ACX downstream primer) and in the detection step, the presence or absence of telomerase is

  15. Coordinated hybrid automatic repeat request

    KAUST Repository

    Makki, Behrooz

    2014-11-01

    We develop a coordinated hybrid automatic repeat request (HARQ) approach. With the proposed scheme, if a user message is correctly decoded in the first HARQ rounds, its spectrum is allocated to other users, to improve the network outage probability and the users\\' fairness. The results, which are obtained for single- and multiple-antenna setups, demonstrate the efficiency of the proposed approach in different conditions. For instance, with a maximum of M retransmissions and single transmit/receive antennas, the diversity gain of a user increases from M to (J+1)(M-1)+1 where J is the number of users helping that user.

  16. [In vitro comparison of root canal preparation with step-back technique and GT rotary file--a nickel-titanium engine driven rotary instrument system].

    Science.gov (United States)

    Krajczár, Károly; Tóth, Vilmos; Nyárády, Zoltán; Szabó, Gyula

    2005-06-01

    The aim of the authors' study was to compare the remaining root canal wall thickness and the preparation time of root canals, prepared either with step-back technique, or with GT Rotary File, an engine driven nickel-titanium rotary instrument system. Twenty extracted molars were decoronated. Teeth were divided in two groups. In Group 1 root canals were prepared with step-back technique. In Group 2 GT Rotary File System was utilized. Preoperative vestibulo-oral X-ray pictures were taken from all teeth with radiovisiograph (RVG). The final preparations at the mesiobuccal canals (MB) were performed with size #30 and palatinal/distal canals with size #40 instruments. Postoperative RVG pictures were taken ensuring the preoperative positioning. The working time was measured in seconds during each preparation. The authors also assessed the remaining root canal wall thickness at 3, 6 and 9 mm from the radiological apex, comparing the width of the canal walls of the vestibulo-oral projections on pre- and postoperative RVG pictures both mesially and buccally. The ratios of the residual and preoperative root canal wall thickness were calculated and compared. The largest difference was found at the MB canals of the coronal and middle third level of the root, measured on the distal canal wall. The ratio of the remaining dentin wall thickness at the coronal and the middle level in the case of step-back preparation was 0.605 and 0.754, and 0.824 and 0.895 in the cases of GT files respectively. The preparation time needed for GT Rotary File System was altogether 68.7% (MB) and 52.5% (D/P canals) of corresponding step-back preparation times. The use of GT Rotary File with comparison of standard step-back method resulted in a shortened preparation time and excessive damage of the coronal part of the root canal could be avoided.

  17. Aberrant ERK 1/2 complex activation and localization in scrapie-infected GT1-1 cells

    Directory of Open Access Journals (Sweden)

    Didonna Alessandro

    2010-08-01

    Full Text Available Abstract Background Fatal neurodegenerative disorders such as Creutzfeldt-Jakob and Gerstmann-Sträussler-Scheinker diseases in humans, scrapie and bovine spongiform encephalopathy in animals, are characterized by the accumulation in the brain of a pathological form of the prion protein (PrP denominated PrPSc. The latter derives from the host cellular form, PrPC, through a process whereby portions of its α-helical and coil structures are refolded into β-sheet structures. Results In this work, the widely known in vitro model of prion replication, hypothalamic GT1-1 cell line, was used to investigate cellular and molecular responses to prion infection. The MAP kinase cascade was dissected to assess the phosphorylation levels of src, MEK 1/2 and ERK 1/2 signaling molecules, both before and after prion infection. Our findings suggest that prion replication leads to a hyper-activation of this pathway. Biochemical analysis was complemented with immunofluorescence studies to map the localization of the ERK complex within the different cellular compartments. We showed how the ERK complex relocates in the cytosol upon prion infection. We correlated these findings with an impairment of cell growth in prion-infected GT1-1 cells as probed by MTT assay. Furthermore, given the persistent urgency in finding compounds able to cure prion infected cells, we tested the effects on the ERK cascade of two molecules known to block prion replication in vitro, quinacrine and Fab D18. We were able to show that while these two compounds possess similar effects in curing prion infection, they affect the MAP kinase cascade differently. Conclusions Taken together, our results help shed light on the molecular events involved in neurodegeneration and neuronal loss in prion infection and replication. In particular, the combination of chronic activation and aberrant localization of the ERK complex may lead to a lack of essential neuroprotective and survival factors

  18. A global conformal extension theorem for perfect fluid Bianchi space-times

    International Nuclear Information System (INIS)

    Luebbe, Christian; Tod, Paul

    2008-01-01

    A global extension theorem is established for isotropic singularities in polytropic perfect fluid Bianchi space-times. When an extension is possible, the limiting behaviour of the physical space-time near the singularity is analysed

  19. Holographic perfect fluidity, Cotton energy-momentum duality and transport properties

    Energy Technology Data Exchange (ETDEWEB)

    Mukhopadhyay, Ayan [Centre de Physique Théorique, Ecole Polytechnique, CNRS UMR 7644,Route de Saclay, 91128 Palaiseau Cedex (France); Institut de Physique Théorique, CEA, CNRS URA 2306,91191 Gif-sur-Yvette (France); Petkou, Anastasios C. [Institute of Theoretical Physics, Department of Physics, Aristotle University of Thessaloniki,54124 Thessaloniki (Greece); Petropoulos, P. Marios; Pozzoli, Valentina [Centre de Physique Théorique, Ecole Polytechnique, CNRS UMR 7644,Route de Saclay, 91128 Palaiseau Cedex (France); Siampos, Konstadinos [Service de Mécanique et Gravitation, Université de Mons, UMONS,20 Place du Parc, 7000 Mons (Belgium)

    2014-04-23

    We investigate background metrics for 2+1-dimensional holographic theories where the equilibrium solution behaves as a perfect fluid, and admits thus a thermodynamic description. We introduce stationary perfect-Cotton geometries, where the Cotton-York tensor takes the form of the energy-momentum tensor of a perfect fluid, i.e. they are of Petrov type D{sub t}. Fluids in equilibrium in such boundary geometries have non-trivial vorticity. The corresponding bulk can be exactly reconstructed to obtain 3+1-dimensional stationary black-hole solutions with no naked singularities for appropriate values of the black-hole mass. It follows that an infinite number of transport coefficients vanish for holographic fluids. Our results imply an intimate relationship between black-hole uniqueness and holographic perfect equilibrium. They also point towards a Cotton/energy-momentum tensor duality constraining the fluid vorticity, as an intriguing boundary manifestation of the bulk mass/nut duality.

  20. Holographic perfect fluidity, Cotton energy-momentum duality and transport properties

    International Nuclear Information System (INIS)

    Mukhopadhyay, Ayan; Petkou, Anastasios C.; Petropoulos, P. Marios; Pozzoli, Valentina; Siampos, Konstadinos

    2014-01-01

    We investigate background metrics for 2+1-dimensional holographic theories where the equilibrium solution behaves as a perfect fluid, and admits thus a thermodynamic description. We introduce stationary perfect-Cotton geometries, where the Cotton-York tensor takes the form of the energy-momentum tensor of a perfect fluid, i.e. they are of Petrov type D t . Fluids in equilibrium in such boundary geometries have non-trivial vorticity. The corresponding bulk can be exactly reconstructed to obtain 3+1-dimensional stationary black-hole solutions with no naked singularities for appropriate values of the black-hole mass. It follows that an infinite number of transport coefficients vanish for holographic fluids. Our results imply an intimate relationship between black-hole uniqueness and holographic perfect equilibrium. They also point towards a Cotton/energy-momentum tensor duality constraining the fluid vorticity, as an intriguing boundary manifestation of the bulk mass/nut duality

  1. A hybrid of monopoly and perfect competition model for hi-tech products

    Science.gov (United States)

    Yang, P. C.; Wee, H. M.; Pai, S.; Yang, H. J.; Wee, P. K. P.

    2010-11-01

    For Hi-tech products, the demand rate, the component cost as well as the selling price usually decline significantly with time. In the case of perfect competition, shortages usually result in lost sales; while in a monopoly, shortages will be completely backordered. However, neither perfect competition nor monopoly exists. Therefore, there is a need to develop a replenishment model considering a hybrid of perfect competition and monopoly when the cost, price and demand are decreasing simultaneously. A numerical example and sensitivity analysis are carried out to illustrate this model. The results show that a higher decline-rate in the component cost leads to a smaller service level and a larger replenishment interval. When the component cost decline rate increases and the selling price decline rate decreases simultaneously, the replenishment interval decreases. In perfect competition it is better to have a high service level, while for the case with monopoly, keeping a low service level is better due to complete backordering.

  2. Mirror-backed Dark Alumina: A Nearly Perfect Absorber for Thermoelectronics and Thermophotovotaics

    KAUST Repository

    Farhat, Mohamed; Cheng, Tsung-Chieh; Le, Khai. Q.; Cheng, Mark Ming-Cheng; Bagci, Hakan; Chen, Pai-Yen

    2016-01-01

    We present here a broadband, wide-angle, and polarization-independent nearly perfect absorber consisting of mirror-backed nanoporous alumina. By electrochemically anodizing the disordered multicomponent aluminum and properly tailoring the thickness

  3. Hypersurface-homogeneous Universe filled with perfect fluid in f ( R ...

    Indian Academy of Sciences (India)

    homogeneous Universe filled with perfect fluid in the framework of f ( R , T ) theory of gravity (Harko et al, \\emph{Phys. Rev.} D 84, 024020 (2011)) is derived. The physical behaviour of the cosmological model is studied.

  4. Femtosecond dynamics of a spaser and unidirectional emission from a perfectly spherical nanoparticle

    KAUST Repository

    Gongora, J. S. Totero

    2015-01-01

    We investigate the femtosecond dynamics of the spaser emission by combining ab-initio simulations and thermodynamic analysis. Interestingly, the emission is characterized by rotational evolution, opening to the generation of unidirectional emission from perfectly spherical nanoparticles. © OSA 2015.

  5. Simulation of a perfect CVD diamond Schottky diode steep forward current–voltage characteristic

    Energy Technology Data Exchange (ETDEWEB)

    Kukushkin, V.A., E-mail: vakuk@appl.sci-nnov.ru [Institute of Applied Physics of the Russian Academy of Science, 46 Ulyanov St., 603950 Nizhny Novgorod (Russian Federation); Nizhny Novgorod State University named after N.I. Lobachevsky, 23 Gagarin pr., 603950 Nizhny Novgorod (Russian Federation)

    2016-10-01

    The kinetic equation approach to the simulation of the perfect CVD diamond Schottky diode current–voltage characteristic is considered. In result it is shown that the latter has a significantly steeper forward branch than that of perfect devices of such a type on usual semiconductors. It means that CVD diamond-based Schottky diodes have an important potential advantage over analogous devices on conventional materials.

  6. Diffraction of love waves by two staggered perfectly weak half-planes

    International Nuclear Information System (INIS)

    Asghar, S.; Zaman, F.D.; Sajida Asghar

    1989-01-01

    Love wave travelling in a layer of uniform thickness overlying a half-space is assumed to be incident on two parallel but staggered perfectly weak half-planes lying in the upper layer. The diffracted fields is calculated using the modified Wiener-Hopf technique and contour integration method. The diffracted waves satisfy the dispersion relations appropriate to different regions formed by the perfectly weak half-planes

  7. INVESTIGATION OF MICROPROCESSOR CURRENT PROTECTION LINES WITH IMPROVED INDICES OF TECHNICAL PERFECTION

    Directory of Open Access Journals (Sweden)

    E. V. Buloichyk

    2014-01-01

    Full Text Available Technical perfection improvement of microprocessor current protection of distribution networks lines is provided by introduction of asymmetrical fault mode determination and fault location functions in the algorithm of its functioning. As a result of computing experiment the basic indices of the technical perfection of current protection have been obtained in the paper. The paper proves high efficiency of the proposed methods that ensure selective and proper operation in the different modes of the controlled line.

  8. Nonparametric additive regression for repeatedly measured data

    KAUST Repository

    Carroll, R. J.; Maity, A.; Mammen, E.; Yu, K.

    2009-01-01

    We develop an easily computed smooth backfitting algorithm for additive model fitting in repeated measures problems. Our methodology easily copes with various settings, such as when some covariates are the same over repeated response measurements

  9. K-FIX(GT): A computer program for modeling the expansion phase of steam explosions within complex three dimensional cavities

    International Nuclear Information System (INIS)

    Hyder, M.L.; Farawila, Y.M.; Abdel-Khalik, S.I.; Halvorson, P.J.

    1992-05-01

    In the development of the Severe Accident Analysis Program for the Savannah River production reactors, it was recognized that certain accidents have the potential for causing damaging steam explosions. The massive SRS reactor buildings are likely to withstand any imaginable steam explosion. However, reactor components and building structures including hatches, ventilation ducts, etc., could be at risk if such an explosion occurred. No tools were available to estimate the effects of such explosions on actual structures. To meet this need, the Savannah River Laboratory contracted with the Georgia Institute of Technology Research Institute for development of a computer-based calculational tool for estimating the effects of steam explosions. The goal for this study was to develop a computer code that could be used parametrically to predict the effects of various steam explosions on their surroundings. This would be able to predict whether a steam explosion of a given magnitude would be likely to fail a particular structure. This would require, of course, that the magnitude of the explosion be specified through some combination of judgment and calculation. The requested code, identified as the K-FIX(GT) code, was developed and delivered by the contractor, along with extensive documentation. The several individual reports that constitute the documentation are each being issued as a separate WSRC report. Documentation includes several model calculations, and representation of these in graphic form. This report gives detailed instructions for the use of the code, including identification of all input parameters required

  10. Temporal profile of estrogen-dependent gene expression in LHRH-producing GT1-7 cells.

    Science.gov (United States)

    Varju, Patricia; Chang, Ken C; Hrabovszky, Erik; Merchenthaler, István; Liposits, Zsolt

    2009-02-01

    The long-term cellular effects of estrogens are mediated by nuclear estrogen receptors which act as transcription factors to regulate gene expression. Hypothalamic targets of estrogen action include luteinizing hormone-releasing hormone-secreting neurons controlling reproduction in vertebrates. Microarray analysis and qRT-PCR studies were performed on GT1-7, immortalized LHRH neurons after 17beta-estradiol treatment to reveal the nature of estrogen-regulated genes and the time course of changes in their expression profile. More than 1000 transcripts showed robust responses to estrogen treatment and the majority of responding genes were up-regulated. Early-responding genes showed altered expression 0.5-2h after estrogen exposure, whereas late-responding genes changed after 24-48h treatment. Up-regulated genes encoded transcription factors, molecules involved in cellular movement, cell death, immune response, neurotransmitter and neuropeptide receptors, ion channels and transporters. The 17beta-estradiol modulation of 12 genes - representing characteristic gene clusters - has been confirmed by qRT-PCR. Our studies highlighted diverse gene networks, cell regulatory mechanisms and metabolic pathways through which estrogen may alter gene expression in immortalized LHRH neurons. The findings also support the notion that genomic effects of estrogen targeting in vivo directly the LHRH neuronal network of mammals play an important role in the central feedback regulation of the reproductive axis by estrogen.

  11. Visualisasi Hasil Mesin Uji Tarik Gotech GT-7010-D2E dalam Bentuk Grafik secara Real Time

    Directory of Open Access Journals (Sweden)

    Anggoro Suryo Pramudyo

    2014-03-01

    Full Text Available Gotech GT-7010-D2E is a tensile testing machine used in Metallurgical Engineering Laboratory UNTIRTA. The machine are used both for practical and Materials Engineering specimen testing demanded by several industries. The machine can perform tensile tests well, but for the analysis is done manually, so it requires a lot of time and accuracy of the analysis results are not very accurate. Therefore, it’s needed a software that can analyze the results of the tensile test in the form of graphs in real time. Software visualization is created using Visual Basic 6.0 and data from tensile testing machine is stored using Microsoft Access database. The software is designed to record any characters that appear in the LCD on the control panel of a tensile testing machine and then process them to be a graphic. Based on the results of the implementation of the specimen plate and wire observations prove that the difference between the use of visualization software is more accurate and effective in their use of time, compared to manual observation that requires further analysis of the test results. In software visualization results of tensile test, the mechanical properties can be analyzed directly from the test results and graphs of data obtained in real time.

  12. Evaluation and optimization of General Atomics' GT-MHR reactor cavity cooling system using an axiomatic design approach

    International Nuclear Information System (INIS)

    Thielman, Jeff; Ge, Ping; Wu, Qiao; Parme, Laurence

    2005-01-01

    The development of the Generation IV (Gen-IV) nuclear reactors has presented social, technical, and economical challenges to nuclear engineering design and research. To develop a robust, reliable nuclear reactor system with minimal environmental impact and cost, modularity has been gradually accepted as a key concept in designing high-quality nuclear reactor systems. While the establishment and reliability of a nuclear power plant is largely facilitated by the installment of standardized base units, the realization of modularity at the sub-system/sub-unit level in a base unit is still highly heuristic, and lacks consistent, quantifiable measures. In this work, an axiomatic design approach is developed to evaluate and optimize the reactor cavity cooling system (RCCS) of General Atomics' Gas Turbine-Modular Helium Reactor (GT-MHR) nuclear reactor, for the purpose of constructing a quantitative tool that is applicable to Gen-IV systems. According to Suh's axiomatic design theory, modularity is consistently represented by functional independence through the design process. Both qualitative and quantitative measures are developed here to evaluate the modularity of the current RCCS design. Optimization techniques are also used to improve the modularity at both conceptual and parametric level. The preliminary results of this study have demonstrated that the axiomatic design approach has great potential in enhancing modular design, and generating more robust, safer, and less expensive nuclear reactor sub-units

  13. Study on Off-Design Steady State Performances of Helium Gas Turbo-compressor for HTGR-GT

    International Nuclear Information System (INIS)

    Qisen Ren; Xiaoyong Yang; Zhiyong Huang; Jie Wang

    2006-01-01

    The high temperature gas-cooled reactor (HTGR) coupled with direct gas turbine cycle is a promising concept in the future of nuclear power development. Both helium gas turbine and compressor are key components in the cycle. Under normal conditions, the mode of power adjustment is to control total helium mass in the primary loop using gas storage vessels. Meanwhile, thermal power of reactor core is regulated. This article analyzes off-design performances of helium gas turbine and compressors for high temperature gas-cooled reactor with gas turbine cycle (HTGR-GT) at steady state level of electric power adjustment. Moreover, performances of the cycle were simply discussed. Results show that the expansion ratio of turbine decreases as electric power reduces but the compression ratios of compressors increase, efficiencies of both turbine and compressors decrease to some extent. Thermal power does not vary consistently with electric power, the difference between these two powers increases as electric power reduces. As a result of much thermal energy dissipated in the temperature modulator set at core inlet, thermal efficiency of the cycle has a widely reduction under partial load conditions. (authors)

  14. Topological characteristics of helical repeat proteins

    NARCIS (Netherlands)

    Groves, M R; Barford, D

    The recent elucidation of protein structures based upon repeating amino acid motifs, including the armadillo motif, the HEAT motif and tetratricopeptide repeats, reveals that they belong to the class of helical repeat proteins. These proteins share the common property of being assembled from tandem

  15. Digital storage of repeated signals

    International Nuclear Information System (INIS)

    Prozorov, S.P.

    1984-01-01

    An independent digital storage system designed for repeated signal discrimination from background noises is described. The signal averaging is performed off-line in the real time mode by means of multiple selection of the investigated signal and integration in each point. Digital values are added in a simple summator and the result is recorded the storage device with the volume of 1024X20 bit from where it can be output on an oscillograph, a plotter or transmitted to a compUter for subsequent processing. The described storage is reliable and simple device on one base of which the systems for the nuclear magnetic resonapce signal acquisition in different experiments are developed

  16. Hungarian repeat station survey, 2010

    Directory of Open Access Journals (Sweden)

    Péter Kovács

    2013-03-01

    Full Text Available The last Hungarian repeat station survey was completed between October 2010 and February 2011. Declination, inclination and the total field were observed using one-axial DMI fluxgate magnetometer mounted on Zeiss20A theodolite and GSM 19 Overhauser magnetometer. The magnetic elements of the sites were reduced to the epoch of 2010.5 on the basis of the continuous recordings of Tihany Geophysical Observatory. In stations located far from the reference observatory, the observations were carried out in the morning and afternoon in order to decrease the effect of the distant temporal correction. To further increase the accuracy, on-site dIdD variometer has also been installed near the Aggtelek station, in the Baradla cave, during the survey of the easternmost sites. The paper presents the technical details and the results of our last campaign. The improvement of the accuracy of the temporal reduction by the use of the local variometer is also reported.

  17. Linear Synchronous Motor Repeatability Tests

    International Nuclear Information System (INIS)

    Ward, C.R.

    2002-01-01

    A cart system using linear synchronous motors was being considered for the Plutonium Immobilization Plant (PIP). One of the applications in the PIP was the movement of a stack of furnace trays, filled with the waste form (pucks) from a stacking/unstacking station to several bottom loaded furnaces. A system was ordered to perform this function in the PIP Ceramic Prototype Test Facility (CPTF). This system was installed and started up in SRTC prior to being installed in the CPTF. The PIP was suspended and then canceled after the linear synchronous motor system was started up. This system was used to determine repeatability of a linear synchronous motor cart system for the Modern Pit Facility

  18. Two-dimensional quantum repeaters

    Science.gov (United States)

    Wallnöfer, J.; Zwerger, M.; Muschik, C.; Sangouard, N.; Dür, W.

    2016-11-01

    The endeavor to develop quantum networks gave rise to a rapidly developing field with far-reaching applications such as secure communication and the realization of distributed computing tasks. This ultimately calls for the creation of flexible multiuser structures that allow for quantum communication between arbitrary pairs of parties in the network and facilitate also multiuser applications. To address this challenge, we propose a two-dimensional quantum repeater architecture to establish long-distance entanglement shared between multiple communication partners in the presence of channel noise and imperfect local control operations. The scheme is based on the creation of self-similar multiqubit entanglement structures at growing scale, where variants of entanglement swapping and multiparty entanglement purification are combined to create high-fidelity entangled states. We show how such networks can be implemented using trapped ions in cavities.

  19. Hybrid FRC under repeated loading

    International Nuclear Information System (INIS)

    Komlos, K.; Babal, B.; Nuernbergerova, T.

    1993-01-01

    Fibre reinforced concretes (FRC) containing several volume fractions in different ratios of two types of fibres - polypropylene and steel, were tested under repeated loading. Mechanical properties of specimens - cubes 150/150/150 mm (for compressive strength), prisms 100/100/400 (for flexural strength), short cylinders 150/60 mm (for impact strength) have been experimentally investigated before and after cyclic loading at the age of 28 days curing time. Mix proportions were designed after DIN 1045 with max. aggregate size 8 mm and grading curve B 8. Portland Cement PC 400 in the amount of 450 kg. m -3 was applied and W/C ratio 0.55. Workability of mixes was measured by Vebe method and regulated by plasticizing admixture Ligoplast Na. Maximum hybrid fibre volume fraction (polypropylene + steel) was 1.0%. Dynamic forces generated in Schenck testing machine with frequency 16 Hz had sinusoidal wave form varying between 0.7 and 0.1 of static mechanical characteristics. The number of cycles in all tests was 10 5 . The residual MOR at static four point bending test and working diagram force-deflection was carried out as well. The impact properties after repeated loading in compression were tested by means of falling weight test. Relationships between composition of fibre composites with different combination of polypropylene (0.2, 0.3, 0.5% by volume) and steel (0.5, 0.7, and 0.8% by volume) fibre content were obtained and technological properties of mixes as well. (author)

  20. Quality control during repeated fryings

    Directory of Open Access Journals (Sweden)

    Cuesta, C.

    1998-08-01

    Full Text Available Most of the debate ¡s about how the slow or frequent turnover of fresh fat affects the deterioration, of fat used in frying. Then, the modification of different oils used in repeated fryings of potatoes without or with turnover of fresh oil, under similar frying conditions, was evaluated by two criteria: by measuring the total polar component isolated by column chromatography and by the evaluation of the specific compounds related to thermoxidative and hydrolytic alteration by High Performance Size Exclusion Chromatography (HPSEC. The results indicate that with frequent turnover of fresh oil, the critical level of 25% of polar material is rarely reached, and there are fewer problems with fat deterioration because the frying tended to increase the level of polar material and thermoxidative compounds (polymers and dimers of triglycerides and oxidized triglycerides in the fryer oil during the first fryings, followed by minor changes and a tendency to reach a near-steady state in successive fryings. However, in repeated frying of potatoes using a null turnover the alteration rate was higher being linear the relationship found between polar material or the different thermoxidative compounds and the number of fryings. On the other hand chemical reactions produced during deep-fat frying can be minimized by using proper oils. In addition the increased level of consumers awareness toward fat composition and its impact on human health could had an impact on the selection of fats for snacks and for industry. In this way monoenic fats are the most adequate from a nutritional point of view and for its oxidative stability during frying.

  1. Tumor Necrosis Factor (TNF) –308G>A, Nitric Oxide Synthase 3 (NOS3) +894G>T Polymorphisms and Migraine Risk: A Meta-Analysis

    Science.gov (United States)

    Chen, Min; Tang, Wenjing; Hou, Lei; Liu, Ruozhuo; Dong, Zhao; Han, Xun; Zhang, Xiaofei; Wan, Dongjun; Yu, Shengyuan

    2015-01-01

    Background and Objective Conflicting data have been reported on the association between tumor necrosis factor (TNF) –308G>A and nitric oxide synthase 3 (NOS3) +894G>T polymorphisms and migraine. We performed a meta-analysis of case-control studies to evaluate whether the TNF –308G>A and NOS3 +894G>T polymorphisms confer genetic susceptibility to migraine. Method We performed an updated meta-analysis for TNF –308G>A and a meta-analysis for NOS3 +894G>T based on studies published up to July 2014. We calculated study specific odds ratios (OR) and 95% confidence intervals (95% CI) assuming allele contrast, dominant model, recessive model, and co-dominant model as pooled effect estimates. Results Eleven studies in 6682 migraineurs and 22591 controls for TNF –308G>A and six studies in 1055 migraineurs and 877 controls for NOS3 +894G>T were included in the analysis. Neither indicated overall associations between gene polymorphisms and migraine risk. Subgroup analyses suggested that the “A” allele of the TNF –308G>A variant increases the risk of migraine among non-Caucasians (dominant model: pooled OR = 1.82; 95% CI 1.15 – 2.87). The risk of migraine with aura (MA) was increased among both Caucasians and non-Caucasians. Subgroup analyses suggested that the “T” allele of the NOS3 +894G>T variant increases the risk of migraine among non-Caucasians (co-dominant model: pooled OR = 2.10; 95% CI 1.14 – 3.88). Conclusions Our findings appear to support the hypothesis that the TNF –308G>A polymorphism may act as a genetic susceptibility factor for migraine among non-Caucasians and that the NOS3 +894G>T polymorphism may modulate the risk of migraine among non-Caucasians. PMID:26098763

  2. On the Contribution of Slovenian Linguistics to the History of the Ancient Greek Perfect

    Directory of Open Access Journals (Sweden)

    Jerneja Kavčič

    2010-12-01

    Full Text Available An important contribution to the history of the Ancient Greek perfect is the study of Erika Mihevc-Gabrovec, The Disappearance of the Perfect in Late Greek (La disparition du parfait dans le grec de la basse époque. In terms of theory and content, her study continues the work of Pierre Chantraine, but somewhat diverges from her predecessor’s views on the issue of the merger between the aorist and the perfect, identifying examples of the use of the perfect even in an – according to Pierre Chantraine – relatively late period.  Some years after the publication of Erika Mihevc-Gabrovec’s book, the question of when the aorist and the perfect may have merged was raised again, to be addressed by McKay in a number of articles. Today, the views on the subject are strongly divided.   As argued by the author of this paper, one of the setbacks in examining the merger between the aorist and the perfect concerns the methodology, since researchers have tended to rely exclusively on their sense of language. A possible new approach is offered in the framework of the Slovenian theory of Natural Syntax, which has from the start paid considerable attention to English sentences of the I believe her to be intelligent type. The paper describes similar sentences in New Testament Greek, terming them “sentences of the λέγουσινἀνάστασινμὴεἶναι type”. In New Testament Greek, they display a tendency to use the present infinitive of stative verbs; relatively frequent is also the perfect infinitive (of non-stative verbs, while, as already noted in other studies, these sentences – at least in New Testament Greek – avoid the aorist infinitive. Such sentences thus bear witness to the fact that the aorist and the perfect were not fully interchangeable in New Testament Greek; the status of the aorist and perfect infinitives in sentences of the λέγουσινἀνάστασινμὴεἶναι type should also be taken into

  3. The leucine-rich repeat structure.

    Science.gov (United States)

    Bella, J; Hindle, K L; McEwan, P A; Lovell, S C

    2008-08-01

    The leucine-rich repeat is a widespread structural motif of 20-30 amino acids with a characteristic repetitive sequence pattern rich in leucines. Leucine-rich repeat domains are built from tandems of two or more repeats and form curved solenoid structures that are particularly suitable for protein-protein interactions. Thousands of protein sequences containing leucine-rich repeats have been identified by automatic annotation methods. Three-dimensional structures of leucine-rich repeat domains determined to date reveal a degree of structural variability that translates into the considerable functional versatility of this protein superfamily. As the essential structural principles become well established, the leucine-rich repeat architecture is emerging as an attractive framework for structural prediction and protein engineering. This review presents an update of the current understanding of leucine-rich repeat structure at the primary, secondary, tertiary and quaternary levels and discusses specific examples from recently determined three-dimensional structures.

  4. Direct and inverted repeats elicit genetic instability by both exploiting and eluding DNA double-strand break repair systems in mycobacteria.

    Directory of Open Access Journals (Sweden)

    Ewelina A Wojcik

    Full Text Available Repetitive DNA sequences with the potential to form alternative DNA conformations, such as slipped structures and cruciforms, can induce genetic instability by promoting replication errors and by serving as a substrate for DNA repair proteins, which may lead to DNA double-strand breaks (DSBs. However, the contribution of each of the DSB repair pathways, homologous recombination (HR, non-homologous end-joining (NHEJ and single-strand annealing (SSA, to this sort of genetic instability is not fully understood. Herein, we assessed the genome-wide distribution of repetitive DNA sequences in the Mycobacterium smegmatis, Mycobacterium tuberculosis and Escherichia coli genomes, and determined the types and frequencies of genetic instability induced by direct and inverted repeats, both in the presence and in the absence of HR, NHEJ, and SSA. All three genomes are strongly enriched in direct repeats and modestly enriched in inverted repeats. When using chromosomally integrated constructs in M. smegmatis, direct repeats induced the perfect deletion of their intervening sequences ~1,000-fold above background. Absence of HR further enhanced these perfect deletions, whereas absence of NHEJ or SSA had no influence, suggesting compromised replication fidelity. In contrast, inverted repeats induced perfect deletions only in the absence of SSA. Both direct and inverted repeats stimulated excision of the constructs from the attB integration sites independently of HR, NHEJ, or SSA. With episomal constructs, direct and inverted repeats triggered DNA instability by activating nucleolytic activity, and absence of the DSB repair pathways (in the order NHEJ>HR>SSA exacerbated this instability. Thus, direct and inverted repeats may elicit genetic instability in mycobacteria by 1 directly interfering with replication fidelity, 2 stimulating the three main DSB repair pathways, and 3 enticing L5 site-specific recombination.

  5. Direct and inverted repeats elicit genetic instability by both exploiting and eluding DNA double-strand break repair systems in mycobacteria.

    Science.gov (United States)

    Wojcik, Ewelina A; Brzostek, Anna; Bacolla, Albino; Mackiewicz, Pawel; Vasquez, Karen M; Korycka-Machala, Malgorzata; Jaworski, Adam; Dziadek, Jaroslaw

    2012-01-01

    Repetitive DNA sequences with the potential to form alternative DNA conformations, such as slipped structures and cruciforms, can induce genetic instability by promoting replication errors and by serving as a substrate for DNA repair proteins, which may lead to DNA double-strand breaks (DSBs). However, the contribution of each of the DSB repair pathways, homologous recombination (HR), non-homologous end-joining (NHEJ) and single-strand annealing (SSA), to this sort of genetic instability is not fully understood. Herein, we assessed the genome-wide distribution of repetitive DNA sequences in the Mycobacterium smegmatis, Mycobacterium tuberculosis and Escherichia coli genomes, and determined the types and frequencies of genetic instability induced by direct and inverted repeats, both in the presence and in the absence of HR, NHEJ, and SSA. All three genomes are strongly enriched in direct repeats and modestly enriched in inverted repeats. When using chromosomally integrated constructs in M. smegmatis, direct repeats induced the perfect deletion of their intervening sequences ~1,000-fold above background. Absence of HR further enhanced these perfect deletions, whereas absence of NHEJ or SSA had no influence, suggesting compromised replication fidelity. In contrast, inverted repeats induced perfect deletions only in the absence of SSA. Both direct and inverted repeats stimulated excision of the constructs from the attB integration sites independently of HR, NHEJ, or SSA. With episomal constructs, direct and inverted repeats triggered DNA instability by activating nucleolytic activity, and absence of the DSB repair pathways (in the order NHEJ>HR>SSA) exacerbated this instability. Thus, direct and inverted repeats may elicit genetic instability in mycobacteria by 1) directly interfering with replication fidelity, 2) stimulating the three main DSB repair pathways, and 3) enticing L5 site-specific recombination.

  6. Studies of a deep burn fuel cycle for the incineration of military plutonium in the GT-MHR using the Monte-Carlo burnup code

    International Nuclear Information System (INIS)

    Talamo, A.; Gudowski, W.

    2004-01-01

    The deep burn fuel cycle for the incineration of military plutonium in the GT-MHR is studied using the Monte-Carlo burnup code. The irradiation is DF is so rich in fissile isotopes that the TF cannot guarantee a negative reactive feedback, and the presence of erbium as burnable poison is absolutely necessary for the reactivity safety reasons. At beginning of life (BOL) the fuel composed of DF, consisting of fresh military plutonium, after an irradiation period of three years the fuel is reprocessed into post driver fuel (PDF). The mass flow of the GT-MHR fuelled by military plutonium at the equilibrium of the fuel composition shows that 66% of 239 Pu is burned in three years and 92% in six years. (authors)

  7. Expression, purification, crystallization and preliminary X-ray characterization of a putative glycosyltransferase of the GT-A fold found in mycobacteria

    Energy Technology Data Exchange (ETDEWEB)

    Fulton, Zara; Crellin, Paul K.; Brammananth, Rajini; Zaker-Tabrizi, Leyla; Coppel, Ross L.; Rossjohna, Jamie; Beddoe, Travis (Monash)

    2008-05-28

    Glycosidic bond formation is a ubiquitous enzyme-catalysed reaction. This glycosyltransferase-mediated process is responsible for the biosynthesis of innumerable oligosaccharides and glycoconjugates and is often organism- or cell-specific. However, despite the abundance of genomic information on glycosyltransferases (GTs), there is a lack of structural data for this versatile class of enzymes. Here, the cloning, expression, purification and crystallization of an essential 329-amino-acid (34.8 kDa) putative GT of the classic GT-A fold implicated in mycobacterial cell-wall biosynthesis are reported. Crystals of MAP2569c from Mycobacterium avium subsp. paratuberculosis were grown in 1.6 M monoammonium dihydrogen phosphate and 0.1 M sodium citrate pH 5.5. A complete data set was collected to 1.8 {angstrom} resolution using synchrotron radiation from a crystal belonging to space group P4{sub 1}2{sub 1}2.

  8. Comparison of cobas HCV GT against Versant HCV Genotype 2.0 (LiPA) with confirmation by Sanger sequencing.

    Science.gov (United States)

    Yusrina, Falah; Chua, Cui Wen; Lee, Chun Kiat; Chiu, Lily; Png, Tracy Si-Yu; Khoo, Mui Joo; Yan, Gabriel; Lee, Guan Huei; Yan, Benedict; Lee, Hong Kai

    2018-05-01

    Correct identification of infecting hepatitis C virus (HCV) genotype is helpful for targeted antiviral therapy. Here, we compared the HCV genotyping performance of the cobas HCV GT assay against the Versant HCV Genotype 2.0 (LiPA) assay, using 97 archived serum samples. In the event of discrepant or indeterminate results produced by either assay, the core and NS5B regions were sequenced. Of the 97 samples tested by the cobas, 25 (26%) were deemed indeterminate. Sequencing analyses confirmed 21 (84%) of the 25 samples as genotype 6 viruses with either subtype 6m, 6n, 6v, 6xa, or unknown subtype. Of the 97 samples tested by the LiPA, thirteen (13%) were deemed indeterminate. Seven (7%) were assigned with genotype 1, with unavailable/inconclusive results from the core region of the LiPA. Notably, the 7 samples were later found to be either genotype 3 or 6 by sequencing analyses. Moreover, 1 sample by the LiPA was assigned as genotypes 4 (cobas: indeterminate) but were later found to be genotype 3 by sequencing analyses, highlighting its limitation in assigning the correct genotype. The cobas showed similar or slightly higher accuracy (100%; 95% CI 94-100%) compared to the LiPA (99%; 95% CI 92-100%). Twenty-six percent of the 97 samples tested by the cobas had indeterminate results, mainly due to its limitation in identifying genotype 6 other than subtypes 6a and 6b. This presents a significant assay limitation in Southeast Asia, where genotype 6 infection is highly prevalent. Copyright © 2018 Elsevier B.V. All rights reserved.

  9. Differential protein expression profile in the hypothalamic GT1-7 cell line after exposure to anabolic androgenic steroids.

    Directory of Open Access Journals (Sweden)

    Freddyson J Martínez-Rivera

    Full Text Available The abuse of anabolic androgenic steroids (AAS has been considered a major public health problem during decades. Supraphysiological doses of AAS may lead to a variety of neuroendocrine problems. Precisely, the hypothalamic-pituitary-gonadal (HPG axis is one of the body systems that is mainly influenced by steroidal hormones. Fluctuations of the hormonal milieu result in alterations of reproductive function, which are made through changes in hypothalamic neurons expressing gonadotropin-releasing hormone (GnRH. In fact, previous studies have shown that AAS modulate the activity of these neurons through steroid-sensitive afferents. To increase knowledge about the cellular mechanisms induced by AAS in GnRH neurons, we performed proteomic analyses of the murine hypothalamic GT1-7 cell line after exposure to 17α-methyltestosterone (17α-meT; 1 μM. These cells represent a good model for studying regulatory processes because they exhibit the typical characteristics of GnRH neurons, and respond to compounds that modulate GnRH in vivo. Two-dimensional difference in gel electrophoresis (2D-DIGE and mass spectrometry analyses identified a total of 17 different proteins that were significantly affected by supraphysiological levels of AAS. Furthermore, pathway analyses showed that modulated proteins were mainly associated to glucose metabolism, drug detoxification, stress response and cell cycle. Validation of many of these proteins, such as GSTM1, ERH, GAPDH, PEBP1 and PDIA6, were confirmed by western blotting. We further demonstrated that AAS exposure decreased expression of estrogen receptors and GnRH, while two important signaling pathway proteins p-ERK, and p-p38, were modulated. Our results suggest that steroids have the capacity to directly affect the neuroendocrine system by modulating key cellular processes for the control of reproductive function.

  10. Hydrogen Fueled Hybrid Solid Oxide Fuel Cell-Gas Turbine (SOFC-GT) System for Long-Haul Rail Application

    Science.gov (United States)

    Chow, Justin Jeff

    Freight movement of goods is the artery for America's economic health. Long-haul rail is the premier mode of transport on a ton-mile basis. Concerns regarding greenhouse gas and criteria pollutant emissions, however, have motivated the creation of annually increasing locomotive emissions standards. Health issues from diesel particulate matter, especially near rail yards, have also been on the rise. These factors and the potential to raise conventional diesel-electric locomotive performance warrants the investigation of using future fuels in a more efficient system for locomotive application. This research evaluates the dynamic performance of a Solid Oxide Fuel Cell-Gas Turbine (SOFC-GT) Hybrid system operating on hydrogen fuel to power a locomotive over a rail path starting from the Port of Los Angeles and ending in the City of Barstow. Physical constraints, representative locomotive operation logic, and basic design are used from a previous feasibility study and simulations are performed in the MATLAB Simulink environment. In-house controls are adapted to and expanded upon. Results indicate high fuel-to-electricity efficiencies of at least 54% compared to a conventional diesel-electric locomotive efficiency of 35%. Incorporation of properly calibrated feedback and feed-forward controls enables substantial load following of difficult transients that result from train kinematics while maintaining turbomachinery operating requirements and suppressing thermal stresses in the fuel cell stack. The power split between the SOFC and gas turbine is deduced to be a deterministic factor in the balance between capital and operational costs. Using hydrogen results in no emissions if renewable and offers a potential of 24.2% fuel energy savings for the rail industry.

  11. Prediction of an optimum biodiesel-diesel blended fuel for compression ignition engine using GT-power

    International Nuclear Information System (INIS)

    Shah, A.N.; Shah, F.H.; Shahid, E.M.; Gardezi, S.A.R.

    2014-01-01

    This paper describes the development of a turbocharged direct-injection compression ignition (CI) engine model using fluid-dynamic engine simulation codes through a simulating tool known as GT Power. The model was first fueled with diesel, and then with various blends of biodiesel and diesel by allotting suitable parameters to predict an optimum blended fuel. During the optimization, main focus was on the engine performance, combustion, and one of the major regulated gaseous pollutants known as oxides of nitrogen (NOx). The combustion parameters such as Premix Duration (DP), Main Duration (DM), Premix Fraction (FP), Main Exponent (EM) and ignition delay (ID) affect the start of injection (SOI) angle, and thus played significant role in the prediction of optimum blended fuel. The SOI angle ranging from 5.2 to 5.7 degree crank angle (DCA) measured before top dead center (TDC) revealed an optimum biodiesel-diesel blend known as B20 (20% biodiesel and 80% diesel by volume). B20 exhibited the minimum possible NOx emissions, better combustion and acceptable engine performance. Moreover, experiments were performed to validate the simulated results by fueling the engine with B20 fuel and operating it on AC electrical dynamometer. Both the experimental and simulated results were in good agreement revealing maximum deviations of only 3%, 3.4%, 4.2%, and 5.1% for NOx, maximum combustion pressure (MCP), engine brake power (BP), and brake specific fuel consumption (BSFC), respectively. Meanwhile, a positive correlation was found between MCP and NOx showing that both the parameters are higher at lower speeds, relative to higher engine speeds. (author)

  12. An In Vitro System Comprising Immortalized Hypothalamic Neuronal Cells (GT1?7 Cells) for Evaluation of the Neuroendocrine Effects of Essential Oils

    OpenAIRE

    Mizuno, Dai; Konoha-Mizuno, Keiko; Mori, Miwako; Yamazaki, Kentaro; Haneda, Toshihiro; Koyama, Hironari; Kawahara, Masahiro

    2015-01-01

    Aromatherapy and plant-based essential oils are widely used as complementary and alternative therapies for symptoms including anxiety. Furthermore, it was reportedly effective for the care of several diseases such as Alzheimer’s disease and depressive illness. To investigate the pharmacological effects of essential oils, we developed an in vitro assay system using immortalized hypothalamic neuronal cells (GT1–7 cells). In this study, we evaluated the effects of essential oils on neuronal deat...

  13. The Perfect Glass Paradigm: Disordered Hyperuniform Glasses Down to Absolute Zero

    Science.gov (United States)

    Zhang, G.; Stillinger, F. H.; Torquato, S.

    2016-11-01

    Rapid cooling of liquids below a certain temperature range can result in a transition to glassy states. The traditional understanding of glasses includes their thermodynamic metastability with respect to crystals. However, here we present specific examples of interactions that eliminate the possibilities of crystalline and quasicrystalline phases, while creating mechanically stable amorphous glasses down to absolute zero temperature. We show that this can be accomplished by introducing a new ideal state of matter called a “perfect glass”. A perfect glass represents a soft-interaction analog of the maximally random jammed (MRJ) packings of hard particles. These latter states can be regarded as the epitome of a glass since they are out of equilibrium, maximally disordered, hyperuniform, mechanically rigid with infinite bulk and shear moduli, and can never crystallize due to configuration-space trapping. Our model perfect glass utilizes two-, three-, and four-body soft interactions while simultaneously retaining the salient attributes of the MRJ state. These models constitute a theoretical proof of concept for perfect glasses and broaden our fundamental understanding of glass physics. A novel feature of equilibrium systems of identical particles interacting with the perfect-glass potential at positive temperature is that they have a non-relativistic speed of sound that is infinite.

  14. Effective high-order solver with thermally perfect gas model for hypersonic heating prediction

    International Nuclear Information System (INIS)

    Jiang, Zhenhua; Yan, Chao; Yu, Jian; Qu, Feng; Ma, Libin

    2016-01-01

    Highlights: • Design proper numerical flux for thermally perfect gas. • Line-implicit LUSGS enhances efficiency without extra memory consumption. • Develop unified framework for both second-order MUSCL and fifth-order WENO. • The designed gas model can be applied to much wider temperature range. - Abstract: Effective high-order solver based on the model of thermally perfect gas has been developed for hypersonic heat transfer computation. The technique of polynomial curve fit coupling to thermodynamics equation is suggested to establish the current model and particular attention has been paid to the design of proper numerical flux for thermally perfect gas. We present procedures that unify five-order WENO (Weighted Essentially Non-Oscillatory) scheme in the existing second-order finite volume framework and a line-implicit method that improves the computational efficiency without increasing memory consumption. A variety of hypersonic viscous flows are performed to examine the capability of the resulted high order thermally perfect gas solver. Numerical results demonstrate its superior performance compared to low-order calorically perfect gas method and indicate its potential application to hypersonic heating predictions for real-life problem.

  15. Økologisk risikovurdering af en genmodificeret glyfosat-tolerant raps GT73 i anmeldelse til godkendelse vedr. import til markedsføring under forordning 1829/2003/EF

    DEFF Research Database (Denmark)

    Kjellsson, Gøsta; Sørensen, Jesper Givskov; Damgaard, Christian

    2012-01-01

    "BIOSCIENCE konklusioner vedr. den økolo-giske risikovurdering af den genmodifice-rede GT73-raps i Danmark Den genmodificerede raps, GT73, adskiller sig fra konventionel raps ved at have indsat gener der gør planten tolerant over for herbicidet glyfosat. Rapsen søges kun godkendt til import til f...... to monitor such dispersal of the GMO-plant into cultivated fields and surroundings. Although, not directly an environmental issue, dispersal of the GT73 could result in problems for co-existence with non-GMO-cultivation. "...

  16. Økologisk risikovurdering af en genmodificeret glyfosat-tolerant raps GT73 i anmeldelse til godkendelse vedr. import til markedsføring under Forordning 1829/2003/EF

    DEFF Research Database (Denmark)

    Damgaard, Christian; Sørensen, Jesper Givskov; Kjellsson, Gøsta

    2012-01-01

    BIOSCIENCE konklusioner vedr. den økolo-giske risikovurdering af den genmodifice-rede GT73-raps i Danmark Den genmodificerede raps, GT73, adskiller sig fra konventionel raps ved at have indsat gener der gør planten tolerant over for herbicidet glyfosat. Rapsen søges kun godkendt til import til fo...... to monitor such dispersal of the GMO-plant into cultivated fields and surroundings. Although, not directly an environmental issue, dispersal of the GT73 could result in problems for co-existence with non-GMO-cultivation....

  17. The Gaze of the Perfect Search Engine: Google as an Infrastructure of Dataveillance

    Science.gov (United States)

    Zimmer, M.

    Web search engines have emerged as a ubiquitous and vital tool for the successful navigation of the growing online informational sphere. The goal of the world's largest search engine, Google, is to "organize the world's information and make it universally accessible and useful" and to create the "perfect search engine" that provides only intuitive, personalized, and relevant results. While intended to enhance intellectual mobility in the online sphere, this chapter reveals that the quest for the perfect search engine requires the widespread monitoring and aggregation of a users' online personal and intellectual activities, threatening the values the perfect search engines were designed to sustain. It argues that these search-based infrastructures of dataveillance contribute to a rapidly emerging "soft cage" of everyday digital surveillance, where they, like other dataveillance technologies before them, contribute to the curtailing of individual freedom, affect users' sense of self, and present issues of deep discrimination and social justice.

  18. Perfect state of Cryptococcus neoformans, Filobasidiella neoformans, on pigeon manure filtrate agar

    Energy Technology Data Exchange (ETDEWEB)

    Staib, F.

    1981-02-01

    To enable studies of the dependence of Cryptococcus neoformans and its perfect and imperfect states upon bird manure as a habitat of this pathogen, a nutrient medium closely resembling natural conditions was prepared. As sole nutrient, the water soluble ingredients of manure from pigeons (Columbia livia) were used. There was no heat sterilization of the manure filtrate. Using a standard pair of C. neoformans strains for mating, it could be demonstrated that the perfect state of the fungus developed on this so called pigeon manure filtrate agar within 48 h at 26 degrees C. This medium is supposed to help in the elucidation of the epidemiological significance of the perfect and imperfect states of this pathogen.

  19. Ultra-broadband and wide-angle perfect absorber based on composite metal-semiconductor grating

    Science.gov (United States)

    Li, Xu; Wang, Zongpeng; Hou, Yumin

    2018-01-01

    In this letter, we present an ultra-broadband and wide-angle perfect absorber based on composite Ge-Ni grating. Near perfect absorption above 90% is achieved in a wide frequency range from 150 nm to 4200 nm, which covers almost the full spectrum of solar radiation. The absorption keeps robust in a wide range of incident angle from 0º to 60º. The upper triangle Ge grating works as an antireflection coating. The lower Ni grating works as a reflector and an effective energy trapper. The guided modes inside Ge grating are excited due to reflection of the lower Ni grating surface. In longer wavelength band, gap surface plasmons (GSPs) in the Ni grating are excited and couple with the guided modes inside the Ge grating. The coupled modes extend the perfect absorption band to the near-infrared region (150 nm-4200 nm). This design has potential application in photovoltaic devices and thermal emitters.

  20. Quantum private query with perfect user privacy against a joint-measurement attack

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Yu-Guang, E-mail: yangyang7357@bjut.edu.cn [College of Computer Science and Technology, Beijing University of Technology, Beijing 100124 (China); State Key Laboratory of Information Security, Institute of Information Engineering, Chinese Academy of Sciences, Beijing 100093 (China); Liu, Zhi-Chao [College of Computer Science and Technology, Beijing University of Technology, Beijing 100124 (China); Li, Jian [School of Computer, Beijing University of Posts and Telecommunications, Beijing 100876 (China); Chen, Xiu-Bo [Information Security Center, State Key Laboratory of Networking and Switching Technology, Beijing University of Posts and Telecommunications, Beijing, 100876 (China); Zuo, Hui-Juan [College of Mathematics and Information Science, Hebei Normal University, Shijiazhuang 050024 (China); Zhou, Yi-Hua; Shi, Wei-Min [College of Computer Science and Technology, Beijing University of Technology, Beijing 100124 (China)

    2016-12-16

    The joint-measurement (JM) attack is the most powerful threat to the database security for existing quantum-key-distribution (QKD)-based quantum private query (QPQ) protocols. Wei et al. (2016) [28] proposed a novel QPQ protocol against the JM attack. However, their protocol relies on two-way quantum communication thereby affecting its real implementation and communication efficiency. Moreover, it cannot ensure perfect user privacy. In this paper, we present a new one-way QPQ protocol in which the special way of classical post-processing of oblivious key ensures the security against the JM attack. Furthermore, it realizes perfect user privacy and lower complexity of communication. - Highlights: • A special classical post-processing ensures the security against the JM attack. • It ensures perfect user privacy. • It ensures lower complexity of communication. Alice's conclusive key rate is 1/6.

  1. Maxwell's fish-eye lens and the mirage of perfect imaging

    International Nuclear Information System (INIS)

    Merlin, R

    2011-01-01

    Recent claims that Maxwell's fish-eye is a perfect lens, capable of providing images with deep subwavelength resolution, are examined. We show that the imaging properties of a dispersionless fish-eye are very similar to those of an ideal spherical cavity. Using this correspondence, we prove that the correct solution to Maxwell equations in the fish-eye gives image sizes that are consistent with the standard diffraction limit. Perfect focusing is an optical illusion that results from placing a time-reversed source at the position of the geometrical image which, when combined with the field due to the primary (object) source, mimics the behavior of a perfect drain. Issues of causality are briefly discussed. We also demonstrate that passive outlets are not a good alternative to time-reversed sources for broadband drain-like behavior and that, even if they were, they could not do a better job than conventional optical systems at providing high resolution

  2. Quantum private query with perfect user privacy against a joint-measurement attack

    International Nuclear Information System (INIS)

    Yang, Yu-Guang; Liu, Zhi-Chao; Li, Jian; Chen, Xiu-Bo; Zuo, Hui-Juan; Zhou, Yi-Hua; Shi, Wei-Min

    2016-01-01

    The joint-measurement (JM) attack is the most powerful threat to the database security for existing quantum-key-distribution (QKD)-based quantum private query (QPQ) protocols. Wei et al. (2016) [28] proposed a novel QPQ protocol against the JM attack. However, their protocol relies on two-way quantum communication thereby affecting its real implementation and communication efficiency. Moreover, it cannot ensure perfect user privacy. In this paper, we present a new one-way QPQ protocol in which the special way of classical post-processing of oblivious key ensures the security against the JM attack. Furthermore, it realizes perfect user privacy and lower complexity of communication. - Highlights: • A special classical post-processing ensures the security against the JM attack. • It ensures perfect user privacy. • It ensures lower complexity of communication. Alice's conclusive key rate is 1/6.

  3. Tethyan Anhydrite Preserved in the Lower Ocean Crust of the Samail Ophiolite? Evidence from Oman Drilling Project Holes GT1A and 2A

    Science.gov (United States)

    Teagle, D. A. H.; Harris, M.; Crispini, L.; Deans, J. R.; Cooper, M. J.; Kelemen, P. B.; Alt, J.; Banerjee, N.; Shanks, W. C., III

    2017-12-01

    Anhydrite is important in mid-ocean ridge hydrothermal systems because of the high concentrations of calcium and sulfate in modern seawater and anhydrite's retrograde solubility. Because anhydrite hosts many powerful tracers of fluid-rock interactions (87Sr/86Sr, δ18O, δ34S, trace elements, fluid inclusions) it is useful for tracing the chemical evolution of hydrothermal recharge fluids and estimating time-integrated fluid fluxes. Anhydrite can form from heated seawater (>100°C), through water-rock reaction, or by mixing of seawater and hydrothermal fluids. Although abundant in active hydrothermal mounds, and predicted to form from downwelling, warming fluids during convection, anhydrite is rare in drill core from seafloor lavas, sheeted dikes and upper gabbros, with only minor amounts in ODP Holes 504B and 1256D. Because anhydrite can dissolve during weathering, its occurrence in ophiolites is unexpected. Instead, gypsum is present in Macquarie Island lavas and Miocene gypsum fills cavities within the Cretaceous Troodos ore deposits. Thus, the occurrence of numerous anhydrite veins in cores from the gabbroic lower crust of the Samail ophiolite in Oman was unanticipated. To our knowledge, anhydrite in Oman gabbros has not been previously reported. Oman Drilling Project Holes GT1A and GT2A were drilled into the Wadi Gideah section of the Wadi Tayin massif. Both recovered 400 m of continuous core from sections of layered gabbros (GT1) and the foliated-layered gabbro transition (GT2). Anhydrite is present throughout both holes, some in vein networks but more commonly as isolated 1-110 mm veins (>60 mm ave). Anhydrite is mostly the sole vein filling but can occur with greenschist minerals such as epidote, quartz, chlorite and prehnite. Anhydrite commonly exhibits prismatic and bladed textures but can also be capriciously microcrystalline. Though definitive cross cutting relationships are elusive, anhydrite veins cut across some greenschist veins. Anhydrite is

  4. The perfect man in the literary opus of John Climacus and Ibn Arabi

    Directory of Open Access Journals (Sweden)

    Rašić Dunja

    2015-01-01

    Full Text Available In search of the perfect man of the Islamic and Christian mysticisms, this paper also discusses the nature of mystical knowledge, to whose domain the perfect man, as the highest model of human existence and spiritual life, indisputably belongs. This study belongs to the philosophical discipline of comparative philosophy. Hence, searching for the lost paradise of human existence, still remembering the taste of bliss of residence filled only with infinite happiness, this paper will consider the extent to which the methodology of Paul Masson-Oursel and Henry Corbin, as two well-known comparative philosophy research methods can try to measure their strength with cryptic teachings of mysticism.

  5. A simple route to scalable fabrication of perfectly ordered ZnO nanorod arrays

    International Nuclear Information System (INIS)

    Liu, D F; Xiang, Y J; Liao, Q; Zhang, J P; Wu, X C; Zhang, Z X; Liu, L F; Ma, W J; Shen, J; Zhou, W Y; Xie, S S

    2007-01-01

    ZnO nanorod arrays with perfect order and uniformity were prepared using a simple, low-cost, commonly available and scalable nanosphere lithography for patterning gold catalyst particles and a successive bottom-up growth technique in a tube furnace chemical vapor deposition system. Each rod in the arrays had perfect surface facets, sharp edges and uniform size. For all of the rods, their sides were oriented the same. This bottom-up assembly method may accelerate the use of ZnO nanorods in real device applications

  6. Analysis of experience of feet functions perfection in rhythmic gymnastic exercises

    Directory of Open Access Journals (Sweden)

    Nesterova T.V.

    2009-10-01

    Full Text Available Trainers and gymnasts take the problem of the special preparation feet and developments of method of its perfection to the number of the actual. The results of the pedagogical testing are shown that basic (basic, pushed, amortisation and specific (aesthetic, manipulation, integral functions feet have a different degree of display. They will be realized in exercises on all of the stages of long-term preparation of sportswomen. Most dynamic perfection of functions feet gymnasts take place on the stages of initial and preliminary base preparation.

  7. Perfect simulation and moment properties for the Matérn type III process

    DEFF Research Database (Denmark)

    Møller, Jesper; Huber, Mark L.; Wolpert, Robert L.

    2010-01-01

    In a seminal work, Bertil Matérn introduced several types of processes for modeling repulsive point processes. In this paper an algorithm is presented for the perfect simulation of the Matérn III process within a bounded window in , fully accounting for edge effects. A simple upper bound on the m......In a seminal work, Bertil Matérn introduced several types of processes for modeling repulsive point processes. In this paper an algorithm is presented for the perfect simulation of the Matérn III process within a bounded window in , fully accounting for edge effects. A simple upper bound...

  8. A corrugated perfect magnetic conductor surface supporting spoof surface magnon polaritons.

    Science.gov (United States)

    Liu, Liang-liang; Li, Zhuo; Gu, Chang-qing; Ning, Ping-ping; Xu, Bing-zheng; Niu, Zhen-yi; Zhao, Yong-jiu

    2014-05-05

    In this paper, we demonstrate that spoof surface magnon polaritons (SSMPs) can propagate along a corrugated perfect magnetic conductor (PMC) surface. From duality theorem, the existence of surface electromagnetic modes on corrugated PMC surfaces are manifest to be transverse electric (TE) mode compared with the transverse magnetic (TM) mode of spoof surface plasmon plaritons (SSPPs) excited on corrugated perfect electric conductor surfaces. Theoretical deduction through modal expansion method and simulation results clearly verify that SSMPs share the same dispersion relationship with the SSPPs. It is worth noting that this metamaterial will have more similar properties and potential applications as the SSPPs in large number of areas.

  9. Effects of Perfectly Correlated and Anti-Correlated Noise in a Logistic Growth Model

    International Nuclear Information System (INIS)

    Zhang Li; Cao Li

    2011-01-01

    The logistic growth model with correlated additive and multiplicative Gaussian white noise is used to analyze tumor cell population. The effects of perfectly correlated and anti-correlated noise on the stationary properties of tumor cell population are studied. As in both cases the diffusion coefficient has zero point in real number field, some special features of the system are arisen. It is found that in both cases, the increase of the multiplicative noise intensity cause tumor cell extinction. In the perfectly anti-correlated case, the stationary probability distribution as a function of tumor cell population exhibit two extrema. (general)

  10. Perfect coupling of light to a periodic dielectric/metal/dielectric structure

    Science.gov (United States)

    Wang, Zhengling; Li, Shiqiang; Chang, R. P. H.; Ketterson, John B.

    2014-07-01

    Using the finite difference time domain method, it is demonstrated that perfect coupling can be achieved between normally incident light and a periodic dielectric/metal/dielectric structure. The structure serves as a diffraction grating that excites modes related to the long range surface plasmon and short range surface plasmon modes that propagate on continuous metallic films. By optimizing the structural dimensions, perfect coupling is achieved between the incident light and these modes. A high Q of 697 and an accompanying ultrasharp linewidth of 0.8 nm are predicted for a 10 nm silver film for optimal conditions.

  11. Preliminary biological sampling of GT3 and BT1 cores and the microbial community dynamics of existing subsurface wells

    Science.gov (United States)

    Kraus, E. A.; Stamps, B. W.; Rempfert, K. R.; Ellison, E. T.; Nothaft, D. B.; Boyd, E. S.; Templeton, A. S.; Spear, J. R.

    2017-12-01

    Subsurface microbial life is poorly understood but potentially very important to the search for life on other planets as well as increasing our understanding of Earth's geobiological processes. Fluids and rocks of actively serpentinizing subsurface environments are a recent target of biological study due to their apparent ubiquity across the solar system. Areas of serpentinization can contain high concentrations of molecular hydrogen, H2, that can serve as the dominant fuel source for subsurface microbiota. Working with the Oman Drilling Project, DNA and RNA were extracted from fluids of seven alkaline wells and two rock cores from drill sites GT3 and BT1 within the Samail ophiolite. DNA and cDNA (produced via reverse transcription from the recovered RNA) were sequenced using universal primers to identify microbial life across all three domains. Alkaline subsurface fluids support a microbial community that changes with pH and host-rock type. In peridotite with pH values of >11, wells NSHQ 14 and WAB 71 have high relative abundances of Meiothermus, Methanobacterium, the family Nitrospiraceae, and multiple types of the class Dehalococcoidia. While also hosted in peridotite but at pH 8.5, wells WAB 104 and 105 have a distinct, more diverse microbial community. This increased variance in community make-up is seen in wells that sit near/at the contact of gabbro and peridotite formations as well. Core results indicate both sampled rock types host a very low biomass environment subject to multiple sources of contamination during the drilling process. Suggestions for contaminant reduction, such as having core handlers wear nitrile gloves and flame-sterilizing the outer surfaces of core rounds for biological sampling, would have minimal impact to overall ODP coreflow and maximize the ability to better understand in situ microbiota in this low-biomass serpentinizing subsurface environment. While DNA extraction was successful with gram amounts of crushed rock, much can be

  12. Identification and characterization of short tandem repeats in the Tibetan macaque genome based on resequencing data.

    Science.gov (United States)

    Liu, San-Xu; Hou, Wei; Zhang, Xue-Yan; Peng, Chang-Jun; Yue, Bi-Song; Fan, Zhen-Xin; Li, Jing

    2018-07-18

    The Tibetan macaque, which is endemic to China, is currently listed as a Near Endangered primate species by the International Union for Conservation of Nature (IUCN). Short tandem repeats (STRs) refer to repetitive elements of genome sequence that range in length from 1-6 bp. They are found in many organisms and are widely applied in population genetic studies. To clarify the distribution characteristics of genome-wide STRs and understand their variation among Tibetan macaques, we conducted a genome-wide survey of STRs with next-generation sequencing of five macaque samples. A total of 1 077 790 perfect STRs were mined from our assembly, with an N50 of 4 966 bp. Mono-nucleotide repeats were the most abundant, followed by tetra- and di-nucleotide repeats. Analysis of GC content and repeats showed consistent results with other macaques. Furthermore, using STR analysis software (lobSTR), we found that the proportion of base pair deletions in the STRs was greater than that of insertions in the five Tibetan macaque individuals (Pgenome showed good amplification efficiency and could be used to study population genetics in Tibetan macaques. The neighbor-joining tree classified the five macaques into two different branches according to their geographical origin, indicating high genetic differentiation between the Huangshan and Sichuan populations. We elucidated the distribution characteristics of STRs in the Tibetan macaque genome and provided an effective method for screening polymorphic STRs. Our results also lay a foundation for future genetic variation studies of macaques.

  13. Repeatability & Workability Evaluation of SIGMOD 2009

    KAUST Repository

    Manegold, Stefan

    2010-12-15

    SIGMOD 2008 was the first database conference that offered to test submitters\\' programs against their data to verify the repeatability of the experiments published [1]. Given the positive feedback concerning the SIGMOD 2008 repeatability initiative, SIGMOD 2009 modified and expanded the initiative with a workability assessment.

  14. simple sequence repeats (EST-SSR)

    African Journals Online (AJOL)

    Yomi

    2012-01-19

    Jan 19, 2012 ... 212 primer pairs selected, based on repeat patterns of n≥8 for di-, tri-, tetra- and penta-nucleotide repeat ... Cluster analysis revealed a high genetic similarity among the sugarcane (Saccharum spp.) breeding lines which could reduce the genetic gain in ..... The multiple allele characteristic of SSR com-.

  15. Repeatability & Workability Evaluation of SIGMOD 2009

    KAUST Repository

    Manegold, Stefan; Manolescu, Ioana; Afanasiev, Loredana; Feng, Jieling; Gou, G.; Hadjieleftheriou, Marios; Harizopoulos, Stavros; Kalnis, Panos; Karanasos, Konstantinos; Laurent, Dominique; Lupu, M.; Onose, N.; Ré , C.; Sans, Virginie; Senellart, Pierre; Wu, T.; Shasha, Dennis E.

    2010-01-01

    SIGMOD 2008 was the first database conference that offered to test submitters' programs against their data to verify the repeatability of the experiments published [1]. Given the positive feedback concerning the SIGMOD 2008 repeatability initiative, SIGMOD 2009 modified and expanded the initiative with a workability assessment.

  16. Inhomogeneous generalizations of Bianchi Type VIh universes with stiff perfect fluid and radiation

    Science.gov (United States)

    Roy, S. R.; Prasad, A.

    1995-03-01

    Families of inhomogeneous models filled with a stiff perfect fluid and radiation have been derived in which there is no flow of total momentum. The models are generalizations of those of Bianchi Type VIh and are discussed for some particular forms of the arbitrary functions appearing in them.

  17. A new RF tagging pulse based on the Frank poly-phase perfect sequence

    DEFF Research Database (Denmark)

    Laustsen, Christoffer; Greferath, Marcus; Ringgaard, Steffen

    2014-01-01

    Radio frequency (RF) spectrally selective multiband pulses or tagging pulses, are applicable in a broad range of magnetic resonance methods. We demonstrate through simulations and experiments a new phase-modulation-only RF pulse for RF tagging based on the Frank poly-phase perfect sequence...

  18. An improvement of an inequality of Ochem and Rao concerning odd perfect numbers

    OpenAIRE

    Zelinsky, Joshua

    2017-01-01

    Let $\\Omega(n)$ denote the total number of prime divisors of $n$ (counting multiplicity) and let $\\omega(n)$ denote the number of distinct prime divisors of $n$. Various inequalities have been proved relating $\\omega(N)$ and $\\Omega(N)$ when $N$ is an odd perfect number. We improve on these inequalities. In particular, we show that if $3 \

  19. Polytropic solutions of a perfect fluid in spatial n-dimensions

    International Nuclear Information System (INIS)

    Luiz, Fabricio Casarejos Lopes; Rocha, Jaime F. Villas da

    2005-01-01

    We found all the solutions of a polytropic state equation for a n-dimensional metric associated to a perfect fluid. Some of them represent gravitational collapse with black hole or naked singularity formation. We found also an accelerating cosmological model. (author)

  20. Bianchi type-I massive string magnetized barotropic perfect fluid

    Indian Academy of Sciences (India)

    Bianchi type-I massive string cosmological model for perfect fluid distribution in the presence of magnetic field is investigated in Rosen's [Gen. Relativ. Gravit. 4, 435 (1973)] bimetric theory of gravitation. To obtain the deterministic model in terms of cosmic time, we have used the condition A = ( B C ) n , where n is a constant, ...

  1. A perfect match? A postcolonial perspective on well educated refugees at the Danish labour market

    DEFF Research Database (Denmark)

    Andersen, Vibeke; Jensen, Iben

    A perfect match? A post colonial perspective on well educated refugees on the Danish labour market In general, integration is hampered if refugees do not have a sufficient educational background to enter the labor market. However, it is estimated by Danish authorities that around 13% of the refug...

  2. Defending perfectionism: Some comments on Quong’s liberalism without perfection

    Directory of Open Access Journals (Sweden)

    Kulenović Enes

    2014-01-01

    Full Text Available The article offers a defense of liberal perfectionism in the light of criticism of perfectionist politics stated in Jonathan Quong’s book Liberalism without Perfection. It argues against Quong’s claims that perfectionism is incompatible with demands of individual autonomy and non-paternalism as requirements of liberal commitment of treating all persons as free and equal.

  3. Bianchi Type-V model with a perfect fluid and Λ-term

    Indian Academy of Sciences (India)

    A self-consistent system of gravitational field with a binary mixture of perfect ... a form of quintessence, may explain the coincidence, adding a new motivation for .... hand, with the expansion of the universe, i.e., with the increase of V , the ...

  4. A Lightweight Anonymous Authentication Protocol with Perfect Forward Secrecy for Wireless Sensor Networks.

    Science.gov (United States)

    Xiong, Ling; Peng, Daiyuan; Peng, Tu; Liang, Hongbin; Liu, Zhicai

    2017-11-21

    Due to their frequent use in unattended and hostile deployment environments, the security in wireless sensor networks (WSNs) has attracted much interest in the past two decades. However, it remains a challenge to design a lightweight authentication protocol for WSNs because the designers are confronted with a series of desirable security requirements, e.g., user anonymity, perfect forward secrecy, resistance to de-synchronization attack. Recently, the authors presented two authentication schemes that attempt to provide user anonymity and to resist various known attacks. Unfortunately, in this work we shall show that user anonymity of the two schemes is achieved at the price of an impractical search operation-the gateway node may search for every possible value. Besides this defect, they are also prone to smart card loss attacks and have no provision for perfect forward secrecy. As our main contribution, a lightweight anonymous authentication scheme with perfect forward secrecy is designed, and what we believe the most interesting feature is that user anonymity, perfect forward secrecy, and resistance to de-synchronization attack can be achieved at the same time. As far as we know, it is extremely difficult to meet these security features simultaneously only using the lightweight operations, such as symmetric encryption/decryption and hash functions.

  5. On some properties of Einstein equations with the perfect fluid energy-momentum tensor

    International Nuclear Information System (INIS)

    Biesiada, M.; Szydlowski, M.; Szczesny, J.

    1989-01-01

    We discuss the symmetries of Einstein equations with the perfect fluid energy momentum tensor. We show that the symmetries inherited from vacuum equations enforce the equation of state in the form p p 0 = γρ which is the most often used one and contains models with the cosmological constant. 9 refs. (author)

  6. Zero-point energy of N perfectly conducting concentric cylindrical shells

    International Nuclear Information System (INIS)

    Tatur, K.; Woods, L.M.

    2008-01-01

    The zero-point (Casimir) energy of N perfectly conducting, infinitely long, concentric cylindrical shells is calculated utilizing the mode summation technique. The obtained convergent expression is studied as a function of size, curvature and number of shells. Limiting cases, such as infinitely close shells or infinite radius shells are also investigated

  7. A Lightweight Anonymous Authentication Protocol with Perfect Forward Secrecy for Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Ling Xiong

    2017-11-01

    Full Text Available Due to their frequent use in unattended and hostile deployment environments, the security in wireless sensor networks (WSNs has attracted much interest in the past two decades. However, it remains a challenge to design a lightweight authentication protocol for WSNs because the designers are confronted with a series of desirable security requirements, e.g., user anonymity, perfect forward secrecy, resistance to de-synchronization attack. Recently, the authors presented two authentication schemes that attempt to provide user anonymity and to resist various known attacks. Unfortunately, in this work we shall show that user anonymity of the two schemes is achieved at the price of an impractical search operation—the gateway node may search for every possible value. Besides this defect, they are also prone to smart card loss attacks and have no provision for perfect forward secrecy. As our main contribution, a lightweight anonymous authentication scheme with perfect forward secrecy is designed, and what we believe the most interesting feature is that user anonymity, perfect forward secrecy, and resistance to de-synchronization attack can be achieved at the same time. As far as we know, it is extremely difficult to meet these security features simultaneously only using the lightweight operations, such as symmetric encryption/decryption and hash functions.

  8. An Instructional Exercise in Cost-Raising Strategies, and Perfect Complements Production

    Science.gov (United States)

    Weisman, Dennis L.

    2007-01-01

    The author presents an account of the 1993 contract negotiations between the United Auto Workers (UAW) and Ford Motor Company to assist students in developing facility with perfect complements production and cost functions and cost-raising strategies. The author seeks an answer to why the UAW targeted Ford for contract negotiations to establish a…

  9. Diffraction of love waves by two parallel perfectly weak half planes

    International Nuclear Information System (INIS)

    Asghar, S.; Zaman, F.D.; Ayub, M.

    1986-04-01

    We consider the diffraction of Love waves by two parallel perfectly weak half planes in a layer overlying a half space. The problem is formulated in terms of the Wiener-Hopf equations in the transformed plane. The transmitted waves are then calculated using the Wiener-Hopf procedure and inverse transforms. (author)

  10. Multi-mode competition in an FEL oscillator at perfect synchronism of an optical cavity

    CERN Document Server

    Dong, Z W; Kii, T; Yamazaki, T; Yoshikawa, K

    2002-01-01

    The sustained saturation in a short pulse free electron laser (FEL) oscillator at perfect synchronism of an optical cavity has been observed recently by Japan Atomic Energy Research Institute (JAERI) FEL group by using their super-conducting linac (Phys. Rev. Lett., in preparation). The experiments have clearly shown that FEL efficiency becomes maximum at perfect synchronism, although it has been considered that only a transient state exists at perfect synchronism due to the lethargy effect. Through careful analyses of the experimental condition of JAERI FEL, we found that, in spite of the short length of the electron micro-bunch, the saturation appears due to the following features, which were different from other FEL experiments: (1) very large ratio of the small signal gain to losses, (2) very long electron macro-bunch which can tolerate a slow start up. The saturation and high efficiency at perfect synchronism were benefited from the contribution of the weak sideband instability. In order to analyse these...

  11. The Perfect Storm: How Policy, Research, and Assessment Will Transform Public Education

    Science.gov (United States)

    McMillan, James H.

    2011-01-01

    In the 2000 movie "The Perfect Storm," there is an unusual convergence of several critical weather factors that set the stage for a destructive outcome that takes both property and lives. It has become a popular metaphor to describe how events come together in a unique way to have an exceptional influence on something, typically a negative impact.…

  12. Higher order equivalent edge currents for fringe wave radar scattering by perfectly conducting polygonal plates

    DEFF Research Database (Denmark)

    Breinbjerg, Olav

    1992-01-01

    An approach for including higher order edge diffraction in the equivalent edge current (EEC) method is proposed. This approach, which applies to monostatic as well as bistatic radar configurations with perfectly conducting polygonal plates, involves three distinct sets of EECs. All of these sets...

  13. Individualization of psychological training and its importance at different stages of many years’ perfection in tennis

    Directory of Open Access Journals (Sweden)

    N.L. Vysochina

    2015-08-01

    Full Text Available Purpose: to determine significance of individualized approach during psychological training at different stages of many years’ perfection in tennis. The tasks of the research were studying of place and role of psychological component in general system of tennis players’ sport training as well as determination of specificities of individualized approach during 14-15 years old and elite tennis players’ psychological training. Material: In the research 24 experts, coaches of combined teams and clubs, elite tennis players took part. Results: Role of psychological training in general system of many years’ perfection has been determined. We also found out that individualization of psychological training in modern tennis is not paid sufficient attention to at present. Most of the questioned respondents pointed, that such training is conducted mainly with elite sportsmen (42%. Only 14% noted that individual psychological training is carried out at basic stages of many years’ perfection. Conclusions: Principle of individualization is a determining one in the course of sportsmen’s training at stages of many years’ perfection. About 86% of experts stressed on significance of application of individualized approach in work with tennis players. Consideration of tennis players’ individual features during psychological training is a compulsory matter in increasing of effectiveness of sportsmen’s training and competition functioning.

  14. Collapsing perfect fluid in self-similar five dimensional space-time and cosmic censorship

    International Nuclear Information System (INIS)

    Ghosh, S.G.; Sarwe, S.B.; Saraykar, R.V.

    2002-01-01

    We investigate the occurrence and nature of naked singularities in the gravitational collapse of a self-similar adiabatic perfect fluid in a five dimensional space-time. The naked singularities are found to be gravitationally strong in the sense of Tipler and thus violate the cosmic censorship conjecture

  15. Perfect simulation and moment properties for the Matérn type III process

    DEFF Research Database (Denmark)

    Møller, Jesper; Huber, Mark L.; Wolpert, Robert L.

    In a seminal work, Bertil Matérn introduced several types of processes for modeling repulsive point processes. In this paper an algorithm is presented for the perfect simulation of the Mat´ern III process within a bounded window in Rd fully accounting for edge effects. A simple upper bound...

  16. Are domestic investors more informed than foreign investors? Evidence from the Perfectly Segmented Market in China

    NARCIS (Netherlands)

    Chan, K.A.; Menkveld, A.J.; Yang, Z.

    2007-01-01

    This paper uses the perfect market segmentation setting in China's stock market to compare the information content of the stock trades of domestic and foreign investors. We study 76 firms that issue both A-shares (for domestic investors) and B-shares (for foreign investors) and compare the price

  17. The Carroll and Chang conjecture of equal Indscal components when Candecomp/Parafac gives perfect fit

    NARCIS (Netherlands)

    Ten Berge, J.M.F.; Stegeman, A.; Bennani-Dosse, M.

    2009-01-01

    The Candecomp/Parafac algorithm approximates a set of matrices X(1),...,X(I), by products of the form AC(i)B', with C(i) diagonal, i = 1,...,I. Carroll and Chang have conjectured that, when the matrices are symmetric, the resulting A and B will be column wise proportional. For cases of perfect fit,

  18. Perfect fluid Bianchi Type-I cosmological models with time varying G ...

    Indian Academy of Sciences (India)

    Abstract. Bianchi Type-I cosmological models containing perfect fluid with time vary- ing G and Λ have been presented. The solutions obtained represent an expansion scalar θ bearing a constant ratio to the anisotropy in the direction of space-like unit vector λi. Of the two models obtained, one has negative vacuum energy ...

  19. UK 2009-2010 repeat station report

    Directory of Open Access Journals (Sweden)

    Thomas J.G. Shanahan

    2013-03-01

    Full Text Available The British Geological Survey is responsible for conducting the UK geomagnetic repeat station programme. Measurements made at the UK repeat station sites are used in conjunction with the three UK magnetic observatories: Hartland, Eskdalemuir and Lerwick, to produce a regional model of the local field each year. The UK network of repeat stations comprises 41 stations which are occupied at approximately 3-4 year intervals. Practices for conducting repeat station measurements continue to evolve as advances are made in survey instrumentation and as the usage of the data continues to change. Here, a summary of the 2009 and 2010 UK repeat station surveys is presented, highlighting the measurement process and techniques, density of network, reduction process and recent results.

  20. In vitro evidence of glucose-induced toxicity in GnRH secreting neurons: high glucose concentrations influence GnRH secretion, impair cell viability, and induce apoptosis in the GT1-1 neuronal cell line.

    Science.gov (United States)

    Pal, Lubna; Chu, Hsiao-Pai; Shu, Jun; Topalli, Ilir; Santoro, Nanette; Karkanias, George

    2007-10-01

    To evaluate for direct toxic effects of high glucose concentrations on cellular physiology in GnRH secreting immortalized GT1-1 neurons. Prospective experimental design. In vitro experimental model using a cell culture system. GT1-1 cells were cultured in replicates in media with two different glucose concentrations (450 mg/dL and 100 mg/dL, respectively) for varying time intervals (24, 48, and 72 hours). Effects of glucose concentrations on GnRH secretion by the GT1-1 neurons were evaluated using a static culture model. Cell viability, cellular apoptosis, and cell cycle events in GT1-1 neurons maintained in two different glucose concentrations were assessed by flow cytometry (fluorescence-activated cell sorter) using Annexin V-PI staining. Adverse influences of high glucose concentrations on GnRH secretion and cell viability were noted in cultures maintained in high glucose concentration (450 mg/dL) culture medium for varying time intervals. A significantly higher percentage of cells maintained in high glucose concentration medium demonstrated evidence of apoptosis by a fluorescence-activated cell sorter. We provide in vitro evidence of glucose-induced cellular toxicity in GnRH secreting GT1-1 neurons. Significant alterations in GnRH secretion, reduced cell viability, and a higher percentage of apoptotic cells were observed in GT1-1 cells maintained in high (450 mg/dL) compared with low (100 mg/dL) glucose concentration culture medium.

  1. Respostas fisiológicas ao déficit hídrico em duas cultivares enxertadas de seringueira ("RRIM 600" e "GT 1" crescidas em campo Physiological responses to water deficit in two young field-grown scion rubber ('RRIM 600' and 'GT 1'

    Directory of Open Access Journals (Sweden)

    Elenice de Cássia Conforto

    2008-06-01

    Full Text Available Sob condições de campo, as plantas estão sujeitas a períodos de déficit hídrico no solo e na atmosfera, durante todo o seu ciclo de vida. Foi avaliado o desempenho de duas cultivares enxertadas de seringueira ("RRIM 600" e "GT 1", mantidas na UNESP-IBILCE, em São José do Rio Preto, SP, com e sem suplementação hídrica, a partir da idade de quatro meses. A resistência máxima ao período seco ininterrupto, considerada quando cessou a realização de fotossíntese com ganho líquido, foi de 17 e 20 dias, respectivamente. Trinta e três dias após a suspensão do estresse, a recuperação das trocas gasosas foi bastante similar para as duas cultivares, e apenas a concentração de dióxido de carbono intercelular retornou a valores equivalentes aos dos controles. Apenas o incremento relativo da área foliar, para "GT 1", e da altura, para "RRIM 600", não diferiram aos do grupo controle (P=0,05. As curvas de resposta à luz indicaram, para ambos os clones, decréscimos para a irradiância de compensação e a taxa fotossintética (P=0,05. Embora parcial, a melhor recuperação após o estresse foi verificada para "GT 1".During their life cycle, plants growing under field condition are subject to periods of air and soil water deficits. In this study was evaluated the performance of two scion cultivar of rubber tree ('RRIM 600' and 'GT 1' growing in São José do Rio Preto, SP, with and without water supplementation since the age of 4 months. The maximum resistance to the uninterrupted dry period, considered when net photosynthesis was ceased, was 17 and 20 days, respectively. Thirty-three days later the water stress was ceased, the gas exchange recovery for both cultivars were quite similar, but just the intercellular carbon dioxide concentration returned to similar values of the control group. Only the relative increment of leaf area to 'GT 1', and plant height of 'RRIM 600' was similar to the control group (P=0.05. The light curve

  2. Repeatability of apparent diffusion coefficient and intravoxel incoherent motion parameters at 3.0 Tesla in orbital lesions

    Energy Technology Data Exchange (ETDEWEB)

    Lecler, Augustin [Fondation Ophtalmologique Adolphe de Rothschild, Department of Radiology, Paris (France); Cardiovascular Research Centre - PARCC, Universite Paris Descartes Sorbonne Paris Cite, INSERM UMR-S970, Paris (France); Savatovsky, Julien; Sadik, Jean-Claude; Charbonneau, Frederique; Berges, Olivier [Fondation Ophtalmologique Adolphe de Rothschild, Department of Radiology, Paris (France); Balvay, Daniel [Cardiovascular Research Centre - PARCC, Universite Paris Descartes Sorbonne Paris Cite, INSERM UMR-S970, Paris (France); Zmuda, Mathieu; Galatoire, Olivier [Fondation Ophtalmologique Adolphe de Rothschild, Department of Orbitopalpebral Surgery, Paris (France); Picard, Herve [Fondation Ophtalmologique Adolphe de Rothschild, Clinical Research Unit, Paris (France); Fournier, Laure [Cardiovascular Research Centre - PARCC, Universite Paris Descartes Sorbonne Paris Cite, INSERM UMR-S970, Paris (France); Universite Paris Descartes Sorbonne Paris Cite, Assistance Publique-Hopitaux de Paris, Hopital Europeen Georges Pompidou, Radiology Department, Paris (France)

    2017-12-15

    To evaluate repeatability of intravoxel incoherent motion (IVIM) diffusion-weighted imaging (DWI) parameters in the orbit. From December 2015 to March 2016, 22 patients were scanned twice using an IVIM sequence with 15b values (0-2,000 s/mm{sup 2}) at 3.0T. Two readers independently delineated regions of interest in an orbital mass and in different intra-orbital and extra-orbital structures. Short-term test-retest repeatability and inter-observer agreement were assessed using the intra-class correlation coefficient (ICC), the coefficient of variation (CV) and Bland-Altman limits of agreements (BA-LA). Test-retest repeatability of IVIM parameters in the orbital mass was satisfactory for ADC and D (mean CV 12% and 14%, ICC 95% and 93%), poor for f and D*(means CV 43% and 110%, ICC 90% and 65%). Inter-observer repeatability agreement was almost perfect in the orbital mass for all the IVIM parameters (ICC = 95%, 93%, 94% and 90% for ADC, D, f and D*, respectively). IVIM appeared to be a robust tool to measure D in orbital lesions with good repeatability, but this approach showed a poor repeatability of f and D*. (orig.)

  3. Repeatability of apparent diffusion coefficient and intravoxel incoherent motion parameters at 3.0 Tesla in orbital lesions

    International Nuclear Information System (INIS)

    Lecler, Augustin; Savatovsky, Julien; Sadik, Jean-Claude; Charbonneau, Frederique; Berges, Olivier; Balvay, Daniel; Zmuda, Mathieu; Galatoire, Olivier; Picard, Herve; Fournier, Laure

    2017-01-01

    To evaluate repeatability of intravoxel incoherent motion (IVIM) diffusion-weighted imaging (DWI) parameters in the orbit. From December 2015 to March 2016, 22 patients were scanned twice using an IVIM sequence with 15b values (0-2,000 s/mm 2 ) at 3.0T. Two readers independently delineated regions of interest in an orbital mass and in different intra-orbital and extra-orbital structures. Short-term test-retest repeatability and inter-observer agreement were assessed using the intra-class correlation coefficient (ICC), the coefficient of variation (CV) and Bland-Altman limits of agreements (BA-LA). Test-retest repeatability of IVIM parameters in the orbital mass was satisfactory for ADC and D (mean CV 12% and 14%, ICC 95% and 93%), poor for f and D*(means CV 43% and 110%, ICC 90% and 65%). Inter-observer repeatability agreement was almost perfect in the orbital mass for all the IVIM parameters (ICC = 95%, 93%, 94% and 90% for ADC, D, f and D*, respectively). IVIM appeared to be a robust tool to measure D in orbital lesions with good repeatability, but this approach showed a poor repeatability of f and D*. (orig.)

  4. [The use of a robot-assisted Gait Trainer GT1 in patients in the acute period of cerebral stroke: a pilot study].

    Science.gov (United States)

    Skvortsova, V I; Ivanova, G E; Kovrazhkina, E A; Rumiantseva, N A; Staritsyn, A N; Suvorov, A Iu; Sogomonian, E K

    2008-01-01

    An aim of the study was to evaluate efficacy of using Gait Trainer GT1, a robot-assisted gait trainer with a system of body-weight support, for the rehabilitation of gait in patients in the acute period of cerebral stroke. A main group included 30 patients in the acute period of ischemic and hemorrhage stroke and a control group--20 age- and sex matched patients. Patients of both groups had daily kinesitherapy sessions with a rehabilitator. Patients of the main group had additional sessions on the Gait Trainer GT1 from the moment of functional readiness to adequate orthostatic probe. Efficacy of rehabilitation was assessed in the four following phases: the first verticalization of patient in the standing position, adaptation of patient to the standing position, walking with assistance, independent walking. Muscular power (scores) in all muscles of low extremities, muscle tonus (the Ashfort scale), amplitude of tendinous reflexes on the reflexes scale, sensory disturbances and discoordination syndromes (specially elaborated scales), pathological positions in the axial muscular system and extremities, functional status (a steadiness scale, the Berg balance scale, the Barthel scale, 5 m test) were assessed in each phase. Stabilometry was conducted for objective evaluation of vertical balance function. The duration of sessions on GT1 and a number of exercises were depended on the patient's tolerability to physical activity. Percentage of relief was determined by the ability of a patient to balance in the standing position. Each patient had 8-10 sessions. A significant improvement of the functional status: ability to balance in standing position, walking, increase of self-care skills were observed in both groups. No significant differences in the level of functional improvements were found compared to the control group. However some peculiarities of the rehabilitation of primary neurologic deficit were observed during CT1-trainings: the normalization of muscle tonus

  5. Metamorphism Near the Dike-Gabbro Transition in the Ocean Crust Based on Preliminary Results from Oman Drilling Project Hole GT3A

    Science.gov (United States)

    Manning, C. E.; Nozaka, T.; Harris, M.; Michibayashi, K.; de Obeso, J. C.; D'Andres, J.; Lefay, R.; Leong, J. A. M.; Zeko, D.; Kelemen, P. B.; Teagle, D. A. H.

    2017-12-01

    Oman Drilling Project Hole GT3A intersected 400 m of altered basaltic dikes, gabbros, and diorites. The 100% recovery affords an unprecedented opportunity to study metamorphism and hydrothermal alteration near the dike-gabbro transition in the ocean crust. Hydrothermal alteration is ubiquitous; all rocks are at least moderately altered, and mean alteration intensity is 54%. The earliest alteration in all rock types is background replacement of igneous minerals, some of which occurred at clinopyroxene amphibolite facies, as indicated by brown-green hornblende, calcic plagioclase, and secondary cpx. In addition, background alteration includes greenschist, subgreenschist, and zeolite facies minerals. More extensive alteration is locally observed in halos around veins, patches, and zones related to deformation. Dense networks of hydrothermal veins record a complex history of fluid-rock alteration. During core description, 10,727 individual veins and 371 vein networks were logged in the 400 m of Hole GT3A. The veins displayed a range of textures and connectivities. The total density of veins in Hole GT3A is 26.8 veins m-1. Vein density shows no correlation with depth, but may be higher near dike margins and faults. Vein minerals include amphibole, epidote, quartz, chlorite, prehnite, zeolite (chiefly laumontite) and calcite in a range of combinations. Analysis of crosscutting relations leads to classification of 4 main vein types. In order of generally oldest to youngest these are: amphibole, quartz-epidote-chlorite (QEC), zeolite-prehnite (ZP), and calcite. QEC and ZP vein types may contain any combination of minerals except quartz alone; veins filled only by quartz may occur at any relative time. Macroscopic amphibole veins are rare and show no variation with depth. QEC vein densities appear to be higher (>9.3 veins m-1) in the upper 300 m of GT3A, where dikes predominate. In contrast, there are 5.5 veins m-1 at 300-400 m, where gabbros and diorites are abundant. ZP

  6. Comparison of computer codes (CE-THERM, FRAP-T5, GT3-FLECHT, and TRUMP-FLECHT) with data from the NRU-LOCA thermal hydraulic tests

    International Nuclear Information System (INIS)

    Mohr, C.L.; Rausch, W.N.; Hesson, G.M.

    1981-07-01

    The LOCA Simulation Program in the NRU reactor is the first set of experiments to provide data on the behavior of full-length, nuclear-heated PWR fuel bundles during the heatup, reflood, and quench phases of a loss-of-coolant accident (LOCA). This paper compares the temperature time histories of 4 experimental test cases with 4 computer codes: CE-THERM, FRAP-T5, GT3-FLECHT, and TRUMP-FLECHT. The preliminary comparisons between prediction and experiment show that the state-of-the art fuel codes have large uncertainties and are not necessarily conservative in predicting peak temperatures, turn around times, and bundle quench times

  7. Development of analog watch with minute repeater

    Science.gov (United States)

    Okigami, Tomio; Aoyama, Shigeru; Osa, Takashi; Igarashi, Kiyotaka; Ikegami, Tomomi

    A complementary metal oxide semiconductor with large scale integration was developed for an electronic minute repeater. It is equipped with the synthetic struck sound circuit to generate natural struck sound necessary for the minute repeater. This circuit consists of an envelope curve drawing circuit, frequency mixer, polyphonic mixer, and booster circuit made by using analog circuit technology. This large scale integration is a single chip microcomputer with motor drivers and input ports in addition to the synthetic struck sound circuit, and it is possible to make an electronic system of minute repeater at a very low cost in comparison with the conventional type.

  8. Preventing Repeat Teen Births PSA (:60)

    Centers for Disease Control (CDC) Podcasts

    This 60 second public service announcement is based on the April 2013 CDC Vital Signs report, which discusses repeat teen births and ways teens, parents and guardians, health care providers, and communities can help prevent them.

  9. An updated meta-analysis of the signal transducer and activator of transcription 4 (STAT4) rs7574865 G/T polymorphism and rheumatoid arthritis risk in an Asian population.

    Science.gov (United States)

    Jiang, X; Zhou, Z; Zhang, Y; Yang, H; Ren, K

    2014-01-01

    Signal transducer and activator of transcription 4 (STAT4) transmits signals induced by the cytokines interleukin (IL)-12, IL-23, and interferon (IFN)-γ, which play an important role in the development of rheumatoid arthritis (RA). Studies have shown conflicting results concerning the association between the rs7574865 G/T polymorphism in the STAT4 gene and RA in an Asian population. We have performed a meta-analysis to examine this relationship. We searched PubMed and WanFang databases for all papers published up to 5 October 2013. Eight case-control studies with 6029 cases and 4685 controls were retrieved based on the search criteria for RA susceptibility related to the STAT4 rs7574865 G/T polymorphism. Risk ratios (RRs) and 95% confidence intervals (CIs) were used to assess the strength of this association. Publication bias was assessed using Begg's test. A significant association was found between the STAT4 rs7574865 G/T polymorphism and RA risk (e.g. GG+GT vs. TT: RR 0.96, 95% CI 0.95-0.97; GG+TT vs. GT: RR 0.94, 95% CI 0.91-0.97). Subgroup analysis of rheumatoid factor (RF) status revealed a protective relationship between the STAT4 rs7574865 G/T polymorphism and RF(+)/RF(-) RA risk. A similar relationship was detected in the anti-cyclic citrullinated peptide (CCP) status subgroup. No clear evidence of publication bias was detected in the overall analysis. Our study indicates that the STAT4 rs7574865 G/T polymorphism was significantly associated with a decreased RA risk in an Asian population.

  10. Digital repeat analysis; setup and operation.

    Science.gov (United States)

    Nol, J; Isouard, G; Mirecki, J

    2006-06-01

    Since the emergence of digital imaging, there have been questions about the necessity of continuing reject analysis programs in imaging departments to evaluate performance and quality. As a marketing strategy, most suppliers of digital technology focus on the supremacy of the technology and its ability to reduce the number of repeats, resulting in less radiation doses given to patients and increased productivity in the department. On the other hand, quality assurance radiographers and radiologists believe that repeats are mainly related to positioning skills, and repeat analysis is the main tool to plan training needs to up-skill radiographers. A comparative study between conventional and digital imaging was undertaken to compare outcomes and evaluate the need for reject analysis. However, digital technology still being at its early development stages, setting a credible reject analysis program became the major task of the study. It took the department, with the help of the suppliers of the computed radiography reader and the picture archiving and communication system, over 2 years of software enhancement to build a reliable digital repeat analysis system. The results were supportive of both philosophies; the number of repeats as a result of exposure factors was reduced dramatically; however, the percentage of repeats as a result of positioning skills was slightly on the increase for the simple reason that some rejects in the conventional system qualifying for both exposure and positioning errors were classified as exposure error. The ability of digitally adjusting dark or light images reclassified some of those images as positioning errors.

  11. DETERMINAÇÃO DOS VALORES MÉDIOS DAS ENZIMAS AST, DHL, gGT E FAS NO SORO DE EQUINOS SADIOS EM SANTA MARIA, RS

    Directory of Open Access Journals (Sweden)

    Sônia Terezinha dos Anjos Lopes

    1993-12-01

    Full Text Available Foram usados 50 eqüinos sadios provenientes do Batalhão de Polícia Montada da Brigada Militar em Santa Maria, RS, sendo 43 machos e 7 fêmeas com idade variadas a partir de 3 anos. Foram colhidos 10ml de sangue da jugular para determinação dos valores da atividade sérica das enzimas aspartato-aminotransferase (AST, desidrogenase lática (DHL, gama-glutamiltransferase (gGT e fosfatase alcalina sérica (FAS. Os resultados encontrados para AST foi de 101 - 190U/I com média de 130UI; DHL foi de 100 - 421 U/l com média de 182U/I; gGT foi de 2 - 27U/I com média de 6.5U/I e FAS foi de 103 - 335U/I com média de 190U/I. A partir de outubro/1992 estes valores passaram a ser referência no laboratório de Patologia Clínica do Hospital de Clinicas Veterinárias da Universidade Federal de Santa Maria.

  12. Expression, purification, crystallization and preliminary X-ray characterization of a putative glycosyltransferase of the GT-A fold found in mycobacteria

    Energy Technology Data Exchange (ETDEWEB)

    Fulton, Zara [The Protein Crystallography Unit, Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, Victoria 3800 (Australia); Australian Research Council Centre of Excellence in Structural and Functional Microbial Genomics, Monash University, Clayton, Victoria 3800 (Australia); Crellin, Paul K.; Brammananth, Rajini [Australian Research Council Centre of Excellence in Structural and Functional Microbial Genomics, Monash University, Clayton, Victoria 3800 (Australia); Department of Microbiology, School of Biomedical Sciences, Monash University, Clayton, Victoria 3800 (Australia); Zaker-Tabrizi, Leyla [The Protein Crystallography Unit, Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, Victoria 3800 (Australia); Australian Research Council Centre of Excellence in Structural and Functional Microbial Genomics, Monash University, Clayton, Victoria 3800 (Australia); Coppel, Ross L. [Australian Research Council Centre of Excellence in Structural and Functional Microbial Genomics, Monash University, Clayton, Victoria 3800 (Australia); Department of Microbiology, School of Biomedical Sciences, Monash University, Clayton, Victoria 3800 (Australia); Rossjohn, Jamie, E-mail: jamie.rossjohn@med.monash.edu.au; Beddoe, Travis, E-mail: jamie.rossjohn@med.monash.edu.au [The Protein Crystallography Unit, Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, Victoria 3800 (Australia); Australian Research Council Centre of Excellence in Structural and Functional Microbial Genomics, Monash University, Clayton, Victoria 3800 (Australia)

    2008-05-01

    MAP2569c from M. avium subsp. paratuberculosis, a putative glycosyltransferase implicated in mycobacterial cell-wall biosynthesis, was cloned, expressed, purified and crystallized. X-ray diffraction data were collected to 1.8 Å resolution. Glycosidic bond formation is a ubiquitous enzyme-catalysed reaction. This glycosyltransferase-mediated process is responsible for the biosynthesis of innumerable oligosaccharides and glycoconjugates and is often organism- or cell-specific. However, despite the abundance of genomic information on glycosyltransferases (GTs), there is a lack of structural data for this versatile class of enzymes. Here, the cloning, expression, purification and crystallization of an essential 329-amino-acid (34.8 kDa) putative GT of the classic GT-A fold implicated in mycobacterial cell-wall biosynthesis are reported. Crystals of MAP2569c from Mycobacterium avium subsp. paratuberculosis were grown in 1.6 M monoammonium dihydrogen phosphate and 0.1 M sodium citrate pH 5.5. A complete data set was collected to 1.8 Å resolution using synchrotron radiation from a crystal belonging to space group P4{sub 1}2{sub 1}2.

  13. Association of the TCF7L2 rs12255372 (G/T variant with type 2 diabetes mellitus in an Iranian population

    Directory of Open Access Journals (Sweden)

    Faranak Mahmoudi Alami

    2012-01-01

    Full Text Available In various populations worldwide, common variants of the TCF7L2 (Transcription factor 7-like 2 gene are associated with the risk of type 2 diabetes mellitus (T2DM. The aim was to investigate the association between rs12255372 (G/T polymorphism in the TCF7L2 gene and T2DM in an Iranian population. 236 unrelated patients with T2DM, and 255 normoglycemic controls without diabetes were studied. The PCR-RFLP method was used for genotyping rs12255372 (G/T polymorphism, and the SPSS version 18.0 for Windows for statistical analysis. The minor T allele of TCF7L2 rs12255372 was found to significantly increase the risk of T2DM, with an allelic odds ratio (OR of 1.458 (95% CI 1.108-1.918, p = 0.007. A significant difference in TT genotype was observed between T2DM patients and normoglycemic controls (OR 2.038, 95% CI 1.147-3.623; p = 0.014. On assuming dominant and recessive models, ORs of 1.52 [95% CI (1.05-2.21 p = 0.026] and 1.74 [95% CI (1.01-3.00 p = 0.043] were obtained, respectively, thereby implying that the co-dominant model would best fit the susceptible gene effect. This study further confirms the TCF7L2 gene as enhancing susceptibility to the development of T2DM.

  14. Expression, purification, crystallization and preliminary X-ray characterization of a putative glycosyltransferase of the GT-A fold found in mycobacteria

    International Nuclear Information System (INIS)

    Fulton, Zara; Crellin, Paul K.; Brammananth, Rajini; Zaker-Tabrizi, Leyla; Coppel, Ross L.; Rossjohn, Jamie; Beddoe, Travis

    2008-01-01

    MAP2569c from M. avium subsp. paratuberculosis, a putative glycosyltransferase implicated in mycobacterial cell-wall biosynthesis, was cloned, expressed, purified and crystallized. X-ray diffraction data were collected to 1.8 Å resolution. Glycosidic bond formation is a ubiquitous enzyme-catalysed reaction. This glycosyltransferase-mediated process is responsible for the biosynthesis of innumerable oligosaccharides and glycoconjugates and is often organism- or cell-specific. However, despite the abundance of genomic information on glycosyltransferases (GTs), there is a lack of structural data for this versatile class of enzymes. Here, the cloning, expression, purification and crystallization of an essential 329-amino-acid (34.8 kDa) putative GT of the classic GT-A fold implicated in mycobacterial cell-wall biosynthesis are reported. Crystals of MAP2569c from Mycobacterium avium subsp. paratuberculosis were grown in 1.6 M monoammonium dihydrogen phosphate and 0.1 M sodium citrate pH 5.5. A complete data set was collected to 1.8 Å resolution using synchrotron radiation from a crystal belonging to space group P4 1 2 1 2

  15. Possibility of perfect concealment by lossy conventional and lossy metamaterial cylindrical invisibility cloaks

    Science.gov (United States)

    Dehbashi, Reza; Shahabadi, Mahmoud

    2013-12-01

    The commonly used coordinate transformation for cylindrical cloaks is generalized. This transformation is utilized to determine an anisotropic inhomogeneous diagonal material tensors of a shell type cloak for various material types, i.e., double-positive (DPS: ɛ, μ > 0), double-negative (DNG: ɛ, μ cloaking for various material types, a rigorous analysis is performed. It is shown that perfect cloaking will be achieved for same type material for the cloak and its surrounding medium. Moreover, material losses are included in the analysis to demonstrate that perfect cloaking for lossy materials can be achieved for identical loss tangent of the cloak and its surrounding material. Sensitivity of the cloaking performance to losses for different material types is also investigated. The obtained analytical results are verified using a Finite-Element computational analysis.

  16. Binary Mixture of Perfect Fluid and Dark Energy in Modified Theory of Gravity

    Science.gov (United States)

    Shaikh, A. Y.

    2016-07-01

    A self consistent system of Plane Symmetric gravitational field and a binary mixture of perfect fluid and dark energy in a modified theory of gravity are considered. The gravitational field plays crucial role in the formation of soliton-like solutions, i.e., solutions with limited total energy, spin, and charge. The perfect fluid is taken to be the one obeying the usual equation of state, i.e., p = γρ with γ∈ [0, 1] whereas, the dark energy is considered to be either the quintessence like equation of state or Chaplygin gas. The exact solutions to the corresponding field equations are obtained for power-law and exponential volumetric expansion. The geometrical and physical parameters for both the models are studied.

  17. Computational study of ammonia adsorption on the perfect and rippled graphene sheet

    International Nuclear Information System (INIS)

    Seyed-Talebi, Seyedeh Mozhgan; Beheshtian, Javad

    2013-01-01

    Adsorption of an ammonia molecule onto perfect and rippled graphene is studied using molecular mechanics calculations. The most stable orientation of an ammonia molecule and equilibrium distance of this molecule over graphene surface (motivated by the recent realization of graphene sensors to detect individual gas molecules) is determined using DFT calculation. This result is in agreement with the predicted molecular mechanics calculation result. It also has been found that (i) the ammonia molecule is weakly adsorbed onto the graphene sheet; (ii) the periodic nature of the potential energy stored between ammonia and perfect graphene is altered due to the sinusoidal ripples; and (iii) the effect of amplitude and wavelength of the one-dimensional created ripple on different energy modes is reported

  18. Perfect-absorption graphene metamaterials for surface-enhanced molecular fingerprint spectroscopy

    Science.gov (United States)

    Guo, Xiangdong; Hu, Hai; Liao, Baoxin; Zhu, Xing; Yang, Xiaoxia; Dai, Qing

    2018-05-01

    Graphene plasmon with extremely strong light confinement and tunable resonance frequency represents a promising surface-enhanced infrared absorption (SEIRA) sensing platform. However, plasmonic absorption is relatively weak (approximately 1%-9%) in monolayer graphene nanostructures, which would limit its sensitivity. Here, we theoretically propose a hybrid plasmon-metamaterial structure that can realize perfect absorption in graphene with a low carrier mobility of 1000 cm2 V-1 s-1. This structure combines a gold reflector and a gold grating to the graphene plasmon structures, which introduce interference effect and the lightning-rod effect, respectively, and largely enhance the coupling of light to graphene. The vibration signal of trace molecules can be enhanced up to 2000-fold at the hotspot of the perfect-absorption structure, enabling the SEIRA sensing to reach the molecular level. This hybrid metal-graphene structure provides a novel path to generate high sensitivity in nanoscale molecular recognition for numerous applications.

  19. A perfect Fresnel acoustic reflector implemented by a Fano-resonant metascreen

    KAUST Repository

    Amin, M.

    2018-04-10

    We propose a perfectly reflecting acoustic metasurface which is designed by replacing the curved segments of the traditional Fresnel reflector by flat Fano-resonant sub-wavelength unit cells. To preserve the original Fresnel focusing mechanism, the unit cell phase follows a specific phase profile which is obtained by applying the generalized Snell\\'s law and Fermat\\'s principle. The reflected curved phase fronts are thus created at the air-metasurface boundary by tailoring the metasurface dispersion as dictated by Huygens\\' principle. Since the unit cells are implemented by sub-wavelength double slit-shaped cavity resonators, the impinging sound waves are perfectly reflected producing acoustic focusing with negligible absorption. We use plane-wave solution and full-wave simulations to demonstrate the focusing effects. The simulation results closely follow the analytical predictions.

  20. Computational study of ammonia adsorption on the perfect and rippled graphene sheet

    Energy Technology Data Exchange (ETDEWEB)

    Seyed-Talebi, Seyedeh Mozhgan [Department of Physics, Shahid Rajaee Teacher Training University, Tehran (Iran, Islamic Republic of); Beheshtian, Javad, E-mail: J.Beheshtian@Srttu.edu [Department of Chemistry, Shahid Rajaee Teacher Training University, Tehran (Iran, Islamic Republic of)

    2013-11-15

    Adsorption of an ammonia molecule onto perfect and rippled graphene is studied using molecular mechanics calculations. The most stable orientation of an ammonia molecule and equilibrium distance of this molecule over graphene surface (motivated by the recent realization of graphene sensors to detect individual gas molecules) is determined using DFT calculation. This result is in agreement with the predicted molecular mechanics calculation result. It also has been found that (i) the ammonia molecule is weakly adsorbed onto the graphene sheet; (ii) the periodic nature of the potential energy stored between ammonia and perfect graphene is altered due to the sinusoidal ripples; and (iii) the effect of amplitude and wavelength of the one-dimensional created ripple on different energy modes is reported.