Pressure-Equalizing Cradle for Booster Rocket Mounting

Science.gov (United States)

Rutan, Elbert L. (Inventor)

2015-01-01

A launch system and method improve the launch efficiency of a booster rocket and payload. A launch aircraft atop which the booster rocket is mounted in a cradle, is flown or towed to an elevation at which the booster rocket is released. The cradle provides for reduced structural requirements for the booster rocket by including a compressible layer, that may be provided by a plurality of gas or liquid-filled flexible chambers. The compressible layer contacts the booster rocket along most of the length of the booster rocket to distribute applied pressure, nearly eliminating bending loads. Distributing the pressure eliminates point loading conditions and bending moments that would otherwise be generated in the booster rocket structure during carrying. The chambers may be balloons distributed in rows and columns within the cradle or cylindrical chambers extending along a length of the cradle. The cradle may include a manifold communicating gas between chambers.

PS Booster - Festive colloquium

CERN Multimedia

2012-01-01

A festive colloquium will be held to celebrate the 40th anniversary of the PS Booster on Friday, 28 September at 2 p.m. in the CERN council chamber. The meeting will be open to everybody. Read more on the PS Booster in the CERN Bulletin and in the CERN Courier.

AGS booster prototype magnets

International Nuclear Information System (INIS)

Danby, G.; Jackson, J.; Lee, Y.Y.; Phillips, R.; Brodowski, J.; Jablonski, E.; Keohane, G.; McDowell, B.; Rodger, E.

1987-01-01

Prototype magnets have been designed and constructed for two half cells of the AGS Booster. The lattice requires 2.4m long dipoles, each curved by 10 0 . The multi-use Booster injector requires several very different standard magnet cycles, capable of instantaneous interchange using computer control from dc up to 10 Hz

AGS Booster prototype magnets

Energy Technology Data Exchange (ETDEWEB)

Danby, G.; Jackson, J.; Lee, Y.Y.; Phillips, R.; Brodowski, J.; Jablonski, E.; Keohane, G.; McDowell, B.; Rodger, E.

1987-03-19

Prototype magnets have been designed and constructed for two half cells of the AGS Booster. The lattice requires 2.4m long dipoles, each curved by 10/sup 0/. The multi-use Booster injector requires several very different standard magnet cycles, capable of instantaneous interchange using computer control from dc up to 10 Hz.

Immunity booster

International Nuclear Information System (INIS)

Stefanescu, Ioan; Titescu, Gheorghe; Tamaian, Radu; Haulica, Ion; Bild, Walther

2002-01-01

The immunity booster is, according to its patent description, microbiologically pure water with an D/(D+H) isotopic concentration of 100 ppm, with physical-chemical characteristics similar to those of distilled water. It is obtained by sterilization of a mixture of deuterium depleted water, with a 25 ppm isotopic concentration, with distilled water in a volume ratio of 4:6. Unlike natural immunity boosters (bacterial agents as Bacillus Chalmette-Guerin, Corynebacterium parvum; lipopolysaccharides; human immunoglobulin) or synthetical products (levamysol; isoprinosyne with immunostimulating action), which cause hypersensitivity and shocks, thrill, fever, sickness and the immunity complex disease, the water of 100 ppm D/(D + H) isotopic concentration is a toxicity free product. The testing for immune reaction of the immunity booster led to the following results: - an increase of cell action capacity in the first immunity shielding stage (macrophages), as evidenced by stimulation of a number of essential characterizing parameters, as well as of the phagocytosis capacity, bactericide capacity, and opsonic capacity of serum; - an increase of the number of leucocyte particularly of the granulocyte in peripheral blood, produced especially when medullar toxic agents like caryolysine are used; - it hinders the effect of lowering the number of erythrocytes in peripheral blood produced by experimentally induced chronic inflammation; - an increase of nonspecific immunity defence capacity against specific bacterial aggression of both Gram-positive bacteria (Streptococcus pneumoniae 558 ) and of the Gram-negative ones (Klebsiella pneumoniae 507 ); - an increase of immunity - stimulating activity (proinflamatory), like that of levamisole as evidenced by the test of stimulation of experimentally induced inflammation by means of carrageenan. The following advantages of the immunity booster are stressed: - it is toxicity free and side effect free; - can be orally administrated as

EVENT DRIVEN AUTOMATIC STATE MODIFICATION OF BNL'S BOOSTER FOR NASA SPACE RADIATION LABORATORY SOLAR PARTICLE SIMULATOR

International Nuclear Information System (INIS)

BROWN, D.; BINELLO, S.; HARVEY, M.; MORRIS, J.; RUSEK, A.; TSOUPAS, N.

2005-01-01

The NASA Space Radiation Laboratory (NSRL) was constructed in collaboration with NASA for the purpose of performing radiation effect studies for the NASA space program. The NSRL makes use of heavy ions in the range of 0.05 to 3 GeV/n slow extracted from BNL's AGS Booster. NASA is interested in reproducing the energy spectrum from a solar flare in the space environment for a single ion species. To do this we have built and tested a set of software tools which allow the state of the Booster and the NSRL beam line to be changed automatically. In this report we will describe the system and present results of beam tests

47 CFR 74.733 - UHF translator signal boosters.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 4 2010-10-01 2010-10-01 false UHF translator signal boosters. 74.733 Section... Translator, and TV Booster Stations § 74.733 UHF translator signal boosters. (a) The licensee of a UHF television broadcast translator station may be authorized to operate one or more signal boosters for the...

Charge exchange injection for Nuclotron and Nuclotron booster

International Nuclear Information System (INIS)

Dinev, D.; Mikhajlov, V.

2000-01-01

The acceleration of polarized beams is between the major items in the JINR LHE's heavy ion superconducting synchrotron Nuclotron research programme. One effective way to increase the intensities of polarized deuteron beams is the application of the charge exchange injection into the Nuclotron. The paper represents the results of a new analytical description of the heavy ion stripping injection based on the Boltzmann kinetic equation. Expressions for the ion density evolution in the transverse phase plane for the emittance growth due to the elastic scattering and to energy losses in the stripping foil and for the number of successfully stored particles have been derived. These results have been applied to the stripping injection of polarized deuterons into the Nuclotron as well as to the stripping injection of heavy ions into the now under consideration Nuclotron rapid cycling booster. It has been shown that an estimated 40-fold intensity gain could be achieved for the stripping injection of polarized D - into the Nuclotron and that an effective stripping injection of light and medium ions into the booster could be realized

Magnetic field errors tolerances of Nuclotron booster

Science.gov (United States)

Butenko, Andrey; Kazinova, Olha; Kostromin, Sergey; Mikhaylov, Vladimir; Tuzikov, Alexey; Khodzhibagiyan, Hamlet

2018-04-01

Generation of magnetic field in units of booster synchrotron for the NICA project is one of the most important conditions for getting the required parameters and qualitative accelerator operation. Research of linear and nonlinear dynamics of ion beam 197Au31+ in the booster have carried out with MADX program. Analytical estimation of magnetic field errors tolerance and numerical computation of dynamic aperture of booster DFO-magnetic lattice are presented. Closed orbit distortion with random errors of magnetic fields and errors in layout of booster units was evaluated.

Integrable RCS as a Proposed Replacement for Fermilab Booster

Energy Technology Data Exchange (ETDEWEB)

Eldred, Jeffrey [Fermilab; Valishev, Alexander [Fermilab

2017-03-07

Integrable optics is an innovation in particle accelerator design that potentially enables a greater betatron tune spread and damps collective instabilities. An integrable rapid-cycling synchrotron (RCS) would be an effective replacement for the Fermilab Booster, as part of a plan to reach multi-MW beam power at 120 GeV for the Fermilab high-energy neutrino program. We provide an example integrable lattice with features of a modern RCS - dispersion-free drifts, low momentum compaction factor, superperiodicity, chromaticity correction, bounded beta functions, and separate-function magnets.

The PS Booster hits 40

CERN Multimedia

Joannah Caborn Wengler

2012-01-01

Many accelerators’ "round" birthdays are being celebrated at CERN these days – the PS turned 50 in 2009, the SPS was 35 in 2011, and this year it's the turn of the PS Booster to mark its 40th anniversary. Originally designed to accelerate 1013 protons to 800 MeV, it has far exceeded its initial design performance over the years.   The PS Booster in the 1970s. Imagine the scene: a group of accelerator physicists staring expectantly at a monitor, when suddenly a shout of joy goes up as a signal flickers across the screen. Does that sound familiar? Well, turn the clock back 40 years (longer hair, wider trouser legs) and you have the situation at the PS Booster on 26 May 1972. On that day, beam was injected into the Booster for the first time. “It was a real buzz,” says Heribert Koziol, then Chairman of the Running-in Committee. “We were very happy – and also a little relieved – when the beam finally...

Laser-plasma booster for ion post acceleration

Directory of Open Access Journals (Sweden)

Satoh D.

2013-11-01

Full Text Available A remarkable ion energy increase is demonstrated for post acceleration by a laser-plasma booster. An intense short-pulse laser generates a strong current by high-energy electrons accelerated, when this intense short-pulse laser illuminates a plasma target. The strong electric current creates a strong magnetic field along the high-energy electron current in plasma. During the increase phase in the magnetic field, a longitudinal inductive electric field is induced for the forward ion acceleration by the Faraday law. Our 2.5-dimensional particle-in-cell simulations demonstrate a remarkable increase in ion energy by several tens of MeV.

The Booster

CERN Multimedia

1972-01-01

Where the beams from the Booster's four rings begin to recombine, before transfer to the PS. On the left are dipoles for vertical steering, and on the right is the tank containing two septum magnets which form the first combining element.

RF cogging in the FNAL Booster Accelerator

International Nuclear Information System (INIS)

William A. Pellico and Robert C. Webber

2000-01-01

The Fermilab Booster operates at a Radio Frequency (RF) harmonic number of 84 with beam in all buckets. One or two bunches of beam are systematically lost in the 8 GeV extraction process as beam is swept across a magnetic septum during the extraction kicker rise time. The prompt radiation and component activation resulting from this localized high energy beam loss become serious concerns as Booster beam throughput must be increased more than tenfold to meet the requirements of RUN II, NUMI, and MiniBooNE experiments. Synchronizing a gap in the beam to the firing of the extraction kickers, a relatively easy and standard practice in many machines, can eliminate the problem. This seemingly simple operation is greatly complicated in the Booster by the need to synchronize extraction to beam already circulating in the Main Injector. Coupled with the inflexibility of the Booster resonant magnetic cycle, cycle to cycle variations, and constraints inherent in the accelerator physics, that requirement forces active control of the gap's azimuthal position throughout the acceleration process as the revolution frequency sweeps rapidly. Until recently, the complexities of actually implementing and demonstrating this process in the Booster had not been worked out. This paper describes a successful demonstration of gap cogging in the Booster

Summary of Booster Development and Qualification Report

Energy Technology Data Exchange (ETDEWEB)

Francois, Elizabeth G. [Los Alamos National Laboratory; Harry, Herbert H. [Los Alamos National Laboratory; Hartline, Ernest L. [Los Alamos National Laboratory; Hooks, Daniel E. [Los Alamos National Laboratory; Johnson, Carl E. [Los Alamos National Laboratory; Morris, John S. [Los Alamos National Laboratory; Novak, Alan M. [Los Alamos National Laboratory; Ramos, Kyle J. [Los Alamos National Laboratory; Sanders, Victor E. [Los Alamos National Laboratory; Scovel, Christina A. [Los Alamos National Laboratory; Lorenz, Thomas [LLNL; Wright, Mark [AWE; Botcher, Tod [PANTEX; Marx, Erin [NSWC-IHDIV; Gibson, Kevin [NSWC-IHDIV

2012-06-21

This report outlines booster development work done at Los Alamos National Laboratory from 2007 to present. The booster is a critical link in the initiation train of explosive assemblies, from complex devices like nuclear weapons to conventional munitions. The booster bridges the gap from a small, relatively sensitive detonator to an insensitive, but massive, main charge. The movement throughout the explosives development community is to use more and more insensitive explosive components. With that, more energy is needed out of the booster. It has to initiate reliably, promptly, powerfully and safely. This report is divided into four sections. The first provides a summary of a collaborative effort between LANL, LLNL, and AWE to identify candidate materials and uniformly develop a testing plan for new boosters. Important parameters and the tests required to measure them were defined. The nature of the collaboration and the specific goals of the participating partners has changed over time, but the booster development plan stands on its own merit as a complete description of the test protocol necessary to compare and qualify booster materials, and is discussed in its entirety in this report. The second section describes a project, which began in 2009 with the Department of Defense to develop replacement booster formulations for PBXN-7. Replacement of PBXN-7 was necessary because it contained Triaminotrinitrobenzene (TATB), which was becoming unavailable to the DoD and because it contained Cyclotrimethylenetrinitramine (RDX), which was sensitive and toxic. A LANL-developed explosive, Diaminoazoxyfurazan (DAAF), was an important candidate. This project required any replacement formulation be a drop-in replacement in existing munitions. This project was timely, in that it made use of the collaborative booster development project, and had the additional constraint of matching shock sensitivity. Additionally it needed to be a safety improvement, and a performance

30 CFR 57.8518 - Main and booster fans.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Main and booster fans. 57.8518 Section 57.8518... and Underground § 57.8518 Main and booster fans. (a) All mine main and booster fans installed and used...-cycle shutdowns or planned or scheduled fan maintenance or fan adjustments where air quality is...

Improvement of seawater booster pump outlet check valve

International Nuclear Information System (INIS)

Li Xuning; Du Yansong; Huang Huimin

2010-01-01

Conventional island seawater booster pump set of QNPC 310 MWe unit are very important in the whole circulating cooling system, and the integrate function of seawater booster pump outlet check valve is the foundation of steady operation of the seawater booster pump set. The article mainly introduce that through the analyses to the reason to the problem that the seawater booster pump outlet check valve of QNPC 310 MWe unit appeared in past years by our team, and considering the influence of operation condition and circumstance, the team improve the seawater booster pump outlet check valve from swing check valve to shuttle check valve which operate more appropriately in the system. By the test of continuous practice, we make further modification to the inner structure of shuttle check valve contrapuntally, and therefore we solve the problem in seawater booster pump outlet check valve fundamentally which has troubled the security of system operation in past years, so we realize the aim of technical improvement and ensure that the system operate in safety and stability. (authors)

Conceptual design report: superconducting booster

International Nuclear Information System (INIS)

1983-01-01

The Superconducting Booster project includes the construction of a new high-voltage injector and buncher for the existing tandem, a magnetic transport system, an rf linac with superconducting resonators, and a rebuncher-debuncher. The booster will fit in existing space so that a new building is not required. The layout of the accelerator is given in Fig. I-1. The University of Washington is contributing approximately $1 M to this project

Thermodynamic investigation of a booster-assisted ejector refrigeration system

International Nuclear Information System (INIS)

Zhao, Hongxia; Zhang, Ke; Wang, Lei; Han, Jitian

2016-01-01

Highlights: • COP based on thermal input increases with booster outlet pressure. • Both entrainment ratio and area ratio increase with booster outlet pressure. • COP based on work is larger than compressor-based refrigeration system. • An optimum booster outlet pressure obtains maximum COP based on work. • Exergy destruction occurs mainly in ejector, condenser, evaporator and generator. - Abstract: In order to improve performance of ejector refrigeration system, a booster is added before an ejector to enhance secondary flow pressure, which is called a booster assisted refrigeration system. Based on mass, momentum and energy conservation, a 1D model of ejector for optimal performance prediction was presented and validated with experimental data. A detailed study of working characteristics of the booster assisted ejector refrigeration system was carried out and compared against conventional ejector refrigeration system and compressor based refrigeration system, on the basis of first and second laws of thermodynamics. Effects of booster outlet pressure on COP_t_h based on thermal energy and COP_w based on work input, and also on entrainment ratio and area ratio of ejector were studied. The exergy destruction rates were also computed and analyzed for components of the booster-assisted ejector refrigeration system. Ways to reduce exergy destruction were discussed.

Gas Test Loop Booster Fuel Hydraulic Testing

International Nuclear Information System (INIS)

Gas Test Loop Hydraulic Testing Staff

2006-01-01

The Gas Test Loop (GTL) project is for the design of an adaptation to the Advanced Test Reactor (ATR) to create a fast-flux test space where fuels and materials for advanced reactor concepts can undergo irradiation testing. Incident to that design, it was found necessary to make use of special booster fuel to enhance the neutron flux in the reactor lobe in which the Gas Test Loop will be installed. Because the booster fuel is of a different composition and configuration from standard ATR fuel, it is necessary to qualify the booster fuel for use in the ATR. Part of that qualification is the determination that required thermal hydraulic criteria will be met under routine operation and under selected accident scenarios. The Hydraulic Testing task in the GTL project facilitates that determination by measuring flow coefficients (pressure drops) over various regions of the booster fuel over a range of primary coolant flow rates. A high-fidelity model of the NW lobe of the ATR with associated flow baffle, in-pile-tube, and below-core flow channels was designed, constructed and located in the Idaho State University Thermal Fluids Laboratory. A circulation loop was designed and constructed by the university to provide reactor-relevant water flow rates to the test system. Models of the four booster fuel elements required for GTL operation were fabricated from aluminum (no uranium or means of heating) and placed in the flow channel. One of these was instrumented with Pitot tubes to measure flow velocities in the channels between the three booster fuel plates and between the innermost and outermost plates and the side walls of the flow annulus. Flow coefficients in the range of 4 to 6.5 were determined from the measurements made for the upper and middle parts of the booster fuel elements. The flow coefficient for the lower end of the booster fuel and the sub-core flow channel was lower at 2.3

Gas Test Loop Booster Fuel Hydraulic Testing

Energy Technology Data Exchange (ETDEWEB)

Gas Test Loop Hydraulic Testing Staff

2006-09-01

The Gas Test Loop (GTL) project is for the design of an adaptation to the Advanced Test Reactor (ATR) to create a fast-flux test space where fuels and materials for advanced reactor concepts can undergo irradiation testing. Incident to that design, it was found necessary to make use of special booster fuel to enhance the neutron flux in the reactor lobe in which the Gas Test Loop will be installed. Because the booster fuel is of a different composition and configuration from standard ATR fuel, it is necessary to qualify the booster fuel for use in the ATR. Part of that qualification is the determination that required thermal hydraulic criteria will be met under routine operation and under selected accident scenarios. The Hydraulic Testing task in the GTL project facilitates that determination by measuring flow coefficients (pressure drops) over various regions of the booster fuel over a range of primary coolant flow rates. A high-fidelity model of the NW lobe of the ATR with associated flow baffle, in-pile-tube, and below-core flow channels was designed, constructed and located in the Idaho State University Thermal Fluids Laboratory. A circulation loop was designed and constructed by the university to provide reactor-relevant water flow rates to the test system. Models of the four booster fuel elements required for GTL operation were fabricated from aluminum (no uranium or means of heating) and placed in the flow channel. One of these was instrumented with Pitot tubes to measure flow velocities in the channels between the three booster fuel plates and between the innermost and outermost plates and the side walls of the flow annulus. Flow coefficients in the range of 4 to 6.5 were determined from the measurements made for the upper and middle parts of the booster fuel elements. The flow coefficient for the lower end of the booster fuel and the sub-core flow channel was lower at 2.3.

Design of the Zero Gradient Synchrotron Booster-II lattice

International Nuclear Information System (INIS)

Crosbie, E.A.; Foss, M.H.; Khoe, T.K.; Simpson, J.D.

1975-01-01

A 500 MeV booster was designed at the Argonne National Laboratory to increase the beam intensity from the Zero Gradient Synchrotron (ZGS). Many turns of H - ions from the 50 MeV linac will be injected into the booster and stripped to H + so that the ring will contain the maximum useful charge in each booster pulse. Several booster pulses will be injected into the ZGS to form one ZGS pulse. This machine is now under construction. (auth)

Compatibility of booster seats and vehicles in the U.S. market.

Science.gov (United States)

Bing, Julie A; Agnew, Amanda M; Bolte, John H

2018-05-19

The objective of this study was to analyze booster and rear vehicle seat dimensions to identify the most frequent compatibility problems. Measurements were collected from 40 high-back and backless boosters and 95 left rear and center rear row seating positions in 50 modern vehicles. Dimensions were compared for 3,800 booster/vehicle seat combinations. For validation and estimation of tolerance and correction factors, 72 booster installations were physically completed and compared with measurement-based compatibility predictions. Dimensions were also compared to the International Organization for Standardization (ISO) volumetric envelopes of forward-facing child restraints and boosters. Seat belt buckles in outboard positions accommodated the width of boosters better than center positions (success rates of 85.4 and 34.7%, respectively). Adequate head restraint clearance occurred in 71.9 to 77.2% of combinations, depending on the booster's head support setting. Booster recline angles aligned properly with vehicle seat cushion angles in 71.5% of combinations. In cases of poor angle alignment, booster angles were more obtuse than the vehicle seat angles 97.7% of the time. Head restraint interference exacerbated angle alignment issues. Data indicate success rates above 90% for boosters being fully supported by the length of the seat cushion and for adequate height clearance with the vehicle roofline. Comparison to ISO envelopes indicates that most boosters on the U.S. market are taller and angled more obtusely than ISO target envelopes. This study quantifies some of the common interferences between boosters and vehicles that may complicate booster usage. Data are useful for design and to prioritize specific problem areas.

Developing the World's Most Powerful Solid Booster

Science.gov (United States)

Priskos, Alex S.; Frame, Kyle L.

2016-01-01

NASA's Journey to Mars has begun. Indicative of that challenge, this will be a multi-decadal effort requiring the development of technology, operational capability, and experience. The first steps are underway with more than 15 years of continuous human operations aboard the International Space Station (ISS) and development of commercial cargo and crew transportation capabilities. NASA is making progress on the transportation required for deep space exploration - the Orion crew spacecraft and the Space Launch System (SLS) heavy-lift rocket that will launch Orion and large components such as in-space stages, habitat modules, landers, and other hardware necessary for deep-space operations. SLS is a key enabling capability and is designed to evolve with mission requirements. The initial configuration of SLS - Block 1 - will be capable of launching more than 70 metric tons (t) of payload into low Earth orbit, greater mass than any other launch vehicle in existence. By enhancing the propulsion elements and larger payload fairings, future SLS variants will launch 130 t into space, an unprecedented capability that simplifies hardware design and in-space operations, reduces travel times, and enhances two solid propellant five-segment boosters, both based on space shuttle technologies. This paper will focus on development of the booster, which will provide more than 75 percent of total vehicle thrust at liftoff. Each booster is more than 17 stories tall, 3.6 meters (m) in diameter and weighs 725,000 kilograms (kg). While the SLS booster appears similar to the shuttle booster, it incorporates several changes. The additional propellant segment provides additional booster performance. Parachutes and other hardware associated with recovery operations have been deleted and the booster designated as expendable for affordability reasons. The new motor incorporates new avionics, new propellant grain, asbestos-free case insulation, a redesigned nozzle, streamlined manufacturing

47 CFR 74.1233 - Processing FM translator and booster station applications.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 4 2010-10-01 2010-10-01 false Processing FM translator and booster station... SERVICES FM Broadcast Translator Stations and FM Broadcast Booster Stations § 74.1233 Processing FM translator and booster station applications. (a) Applications for FM translator and booster stations are...

Superconducting racetrack booster for the ion complex of MEIC

Energy Technology Data Exchange (ETDEWEB)

Filatov, Yu [Joint Inst. for Nuclear Research (JINR), Dubna (Russian Federation); Moscow Inst. of Physics and Technology (MIPT), Moscow (Russian Federation); Kondratenko, A. M. [Science and Technique Laboratory ' Zaryad' , 630090, Novosibirsk, Russia; Kondratenko, M. A. [Science and Technique Laboratory ' Zaryad' , 630090, Novosibirsk, Russia; Kovalenko, A. [Joint Inst. for Nuclear Research (JINR), Dubna (Russian Federation); Derbenev, Yaroslav S. [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Lin, Fanglei [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Morozov, Vasiliy S. [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Zhang, Yuhong [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States)

2016-02-01

The current design of the Medium-energy Electron-Ion Collider (MEIC) project at Jefferson lab features a single 8 GeV/c figure-8 booster based on super-ferric magnets. Reducing the circumference of the booster by switching to a racetrack design may improve its performance by limiting the space charge effect and lower its cost. We consider problems of preserving proton and deuteron polarizations in a superconducting racetrack booster. We show that using magnets based on hollow high-current NbTi composite superconducting cable similar to those designed at JINR for the Nuclotron guarantees preservation of the ion polarization in a racetrack booster up to 8 GeV/c. The booster operation cycle would be a few seconds that would improve the operating efficiency of the MEIC ion complex.

Object-oriented programming techniques for the AGS Booster

International Nuclear Information System (INIS)

Skelly, J.F.

1991-01-01

The applications software developed for the control system of the AGS Booster Project was written in the object-oriented language, C++. A the start of the Booster Project, the programming staff of the AGS Controls Section comprised some dozen programmer/analysts, all highly fluent in C but novices in C++. During the coarse of this project, nearly the entire staff converted to using C++ for a large fraction of their assignments. Over 100 C++ software modules are now available for Booster and general AGS use, of which a large fraction are broadly applicable tools. The transition from C to C++ from a managerial perspective is discussed and an overview is provided of the ways in which object classes have been applied in Booster software development

Object-oriented programming techniques for the AGS Booster

International Nuclear Information System (INIS)

Skelly, J.F.

1992-01-01

The applications software developed for the control system of the AGS Booster Project was written in the object-oriented language, C++. At the start of the Booster Project, the programming staff of the AGS Controls Section comprised some dozen programmer/analysts, all highly fluent in C but novices in C++. During the course of this project, nearly the entire staff converted to using C++ for a large fraction of their assignments. Over 100 C++ software modules are now available both for Booster and general AGS use, of which a large fraction are broadly applicable tools. The transition from C to C++ from a managerial perspective is discussed and an overview is provided of the ways in which object classes have been applied in Booster software development. (author)

LS1 Report: first beams in the Booster

CERN Multimedia

Anaïs Schaeffer

2014-01-01

On Monday, 2 June, the Operations Group injected the first beams into the PS Booster (PSB). The PSB, the second machine in the LHC injector chain to be recommissioned (Linac2 was the first), also provides beams for non-LHC experiments, some of which will need beams for physics as early as this summer.   The PS Booster. The Operations Group has been back in control of the PS Booster for a month now, having taken over where the engineers and experts of the EN Department, who were responsible for the maintenance work, left off. The group first ran tests with no beam (known as “cold check-out”) to check and requalify all the machine instrumentation, from the control room to the ring itself. Now in beam mode, the Booster is being prepared both to begin supplying the PS at the end of June and, above all, for physics to restart in the ISOLDE experimental area. The PS Booster console in the CERN Control Centre. “We have around 15 types of beams to ‘prepa...

LS1 Report: PS Booster prepares for beam

CERN Multimedia

Katarina Anthony

2014-01-01

With Linac2 already up and running, the countdown to beam in the LHC has begun! The next in line is the PS Booster, which will close up shop to engineers early next week. The injector will be handed over to the Operations Group who are tasked with getting it ready for active duty.   Taken as we approach the end of LS1 activities, this image shows where protons will soon be injected from Linac2 into the four PS Booster rings. Over the coming two months, the Operations Group will be putting the Booster's new elements through their paces. "Because of the wide range of upgrades and repairs carried out in the Booster, we have a very full schedule of tests planned for the machine," says Bettina Mikulec, PS Booster Engineer in Charge. "We will begin with cold checks; these are a wide range of tests carried out without beam, including system tests with power on/off and with varying settings, as well as verification of the controls system and timings." Amon...

A study on the particle penetration in RMS Right Single Quotation Marks particle transport system

International Nuclear Information System (INIS)

Son, S. M.; Oh, S. H.; Choi, C. R.

2014-01-01

In nuclear facilities, a radiation monitoring system (RMS) monitors the exhaust gas containing the radioactive material. Samples of exhaust gas are collected in the downstream region of air cleaning units (ACUs) in order to examine radioactive materials. It is possible to predict an amount of radioactive material by analyzing the corrected samples. Representation of the collected samples should be assured in order to accurately sense and measure of radioactive materials. The radius of curvature is mainly 5 times of tube diameter. Sometimes, a booster fan is additionally added to enhance particle penetration rate... In this study, particle penetrations are calculated to evaluate particle penetration rate with various design parameters (tube lengths, tube declined angles, radius of curvatures, etc). The particle penetration rates have been calculated for several elements in the particle transport system. In general, the horizontal length of tube and the number of bending tube have a big impact on the penetration rate in the particle transport system. If the sampling location is far from the radiation monitoring system, additional installation of booster fans could be considered in case of large diameter tubes, but is not recommended in case of small diameter tube. In order to enhance particle penetration rate, the following works are recommended by priority. 1) to reduce the interval between sampling location and radiation monitoring system 2) to reduce the number of the bending tube

The AGS Booster control system

International Nuclear Information System (INIS)

Frankel, R.; Auerbach, E.; Culwick, B.; Clifford, T.; Mandell, S.; Mariotti, R.; Salwen, C.; Schumburg, N.

1988-01-01

Although moderate in size, the Booster construction project requires a comprehensive control system. There are three operational modes: as a high intensity proton injector for the AGS, as a heavy ion accelerator and injector supporting a wide range of ions and as a polarized proton storage injector. These requirements are met using a workstation based extension of the existing AGS control system. Since the Booster is joining a complex of existing accelerators, the new system will be capable of supporting multiuser operational scenarios. A short discussion of this system is discussed in this paper

Transversely-biased ferrite-tuned cavity for the SSC booster

International Nuclear Information System (INIS)

Carlini, R.D.; Friedrichs, C. Jr.; Thiessen, H.A.

1985-01-01

Ferrite tuning of rf cavities is used to provide the change in frequency necessary as the velocity of particles in synchrotrons increases. A new technique in which the ferrite bias field is applied in a direction perpendicular to the rf field offers the possibility of greatly reducing the rf power dissipation in the ferrite. A possible 60 MHz design is discussed for the SSC booster. The cavity design is based on a simple coaxial quarter-wave resonator. A brief discussion is given fo the theory of perpendicular biasing. The measured electric Q's of five different microwave-type ferrite samples are reported and compared with the manufacturer's specifications. 9 fig

Beam instrumentation in the AGS Booster

International Nuclear Information System (INIS)

Witkover, R.L.

1991-01-01

The AGS Booster was designed to accelerate low intensity (2 x 10 10 ) polarized protons, high intensity (1.5x10 13 ) protons and heavy ions through Au +33 . Coping with this wide range of beams, the 3 x 10 -11 Torr vacuum and the radiation environment presented challenges for the beam monitors. Some of the more interesting instrumentation design and performance during the recent Booster proton commissioning will be described

Booster Vaccination: The Role of Reduced Antigen Content Vaccines as a Preschool Booster

Directory of Open Access Journals (Sweden)

Giovanni Gabutti

2014-01-01

Full Text Available The need for boosters for tetanus, diphtheria, pertussis, and polio, starting from preschool age, is related to the waning immune protection conferred by vaccination, the elimination/reduction of natural boosters due to large-scale immunization programs, and the possibility of reintroduction of wild agents from endemic areas. Taking into account the relevance of safety/tolerability in the compliance with vaccination among the population, it have been assessed whether today enough scientific evidences are available to support the use of dTap-IPV booster in preschool age. The review of the literature was conducted using the PubMed search engine. A total of 41 works has been selected; besides, the documentation produced by the World Health Organization, the European Centre for Disease Control, and the Italian Ministry of Health has been consulted. Many recent papers confirm the opportunity to use a low antigenic dose vaccine starting from 4 to 6 years of age. There is also evidence that 10 years after immunization the rate of seroprotected subjects against diphtheria does not differ significantly between those vaccinated with paediatric dose (DTaP or reduced dose (dTaP or dTap product. The dTpa vaccine is highly immunogenic for diphtheria toxoids regardless of prior vaccination history (2 + 1 and 3 + 1 schedules.

Subcriticality determination in ADS: Valina-Booster experiments

International Nuclear Information System (INIS)

Persson, C. M.; Gudowski, W.; Fokau, A.; Bournos, V.; Fokov, Y.; Routkovskaia, C.; Serafimovich, I.; Kiyavitskaya, H.

2007-01-01

A major problem in operating a full-scale subcritical accelerator-driven system (ADS) is to ensure sufficient margin to criticality. Therefore, reliable techniques for subcriticality monitoring are required. In order to develop such techniques, a full understanding of existing reactivity determination methods is essential. In this work, reactivity determination methods, such as pulsed neutron source methods and noise methods, are studied experimentally in the subcritical facility YALINA-Booster. YALINA-Booster: The subcritical assembly YALINA-Booster: recently constructed at the Joint Institute for Power and Nuclear Research - Sosny, consists of a subcritical core driven by an external neutron source. The neutron source is a powerful neutron generator consisting of a deuteron accelerator and a target of deuterium or tritium embedded in titanium. Through (d, d) - or (d, t)-reactions neutrons are created with energy around 2.5 MeV and 14.1 MeV respectively. Neutrons are born in the centre of the core and multiply through a lead matrix fuelled with highly enriched uranium (90% and 36%). This zone is referred to as the booster zone and is surrounded by a thermal zone, moderated by polyethylene. In order to reach sufficient high effective multiplication factor, the thermal zone is fuelled by approximately one thousand rods of 10% enriched uranium dioxide in cylindrical geometry. To prevent thermal neutrons from diffusing into the fast booster zone, an interface, consisting of boron carbide and natural uranium rods, is located between the zones. YALINA-Booster has a radial graphite reflector of thickness 24 cm. Experiments: Experiments using the neutron source in pulsed mode will be presented, relying on methods such as the area method and the method of prompt neutron decay rate determination. Moreover, results from noise analysis using for instance the Feynman-α method will be presented

Booster LINAC project: introduction

International Nuclear Information System (INIS)

Storm, D.W.

1984-01-01

During the past year the DOE awarded a contract to build the superconducting booster proposed in 1982. Although the majority of the funds ($8M) of the project are construction funds included in the DOE contract, part of the project is to be done with state funds ($1.03M) and part with the operating funds (3 FTE personnel as well as costs of prototyping the resonators). Therefore it is appropriate to outline the progress in this report. The overall design was changed somewhat from that described in last year's Annual Report. Instead of 12 split ring resonators optimized for beta = 0.10 and 12 for beta = 0.16, the author has chosen to use 16 quarter wave resonators optimized for beta = 0.09 and 16 for beta = 0.18. The quarter wave resonators, which have two accelerating gaps instead of the three of the split rings, have a wider transit time factor, which is favorable for accelerating a broader range of particle masses. The quarter wave resonators are to be built of lead plated copper, following the design of Ben-Zvi and Brennan

Space shuttle booster separation motor design

Science.gov (United States)

Smith, G. W.; Chase, C. A.

1976-01-01

The separation characteristics of the space shuttle solid rocket boosters (SRBs) are introduced along with the system level requirements for the booster separation motors (BSMs). These system requirements are then translated into specific motor requirements that control the design of the BSM. Each motor component is discussed including its geometry, material selection, and fabrication process. Also discussed is the propellant selection, grain design, and performance capabilities of the motor. The upcoming test program to develop and qualify the motor is outlined.

An efficiency booster for energy conversion in natural circulation loops

Energy Technology Data Exchange (ETDEWEB)

Wang, Dongqing, E-mail: wangdongqing@stu.xjtu.edu.cn [School of Nuclear Science and Technology, Xi’an Jiaotong University, Xi’an, Shaanxi 710049 (China); Beijing Computational Science Research Center, Beijing 100084 (China); Jiang, Jin, E-mail: jjiang@eng.uwo.ca [Department of Electrical and Computer Engineering, The University of Western Ontario, London, Ontario N6A 5B9 (Canada); Beijing Computational Science Research Center, Beijing 100084 (China)

2016-08-01

Highlights: • Low driving power conversion efficiency of natural circulation loops is proved. • The low conversion efficiency leads to low heat transfer capacity of such loops. • An efficiency booster is designed with turbine to increase the efficiency. • Performance of the proposed booster has been numerically simulated. • The booster drastically enhances heat transfer capacity of such loops. - Abstract: In this paper, the capacity of a natural circulation loop for transferring heat from a heat source to a heat sink has been analyzed. It is concluded that the capacity of the natural circulation loop depends on the conversion efficiency of the thermal energy from the heat source to the driving force for the circulation of the flow. The low conversion efficiency leading to weak driving force in such loops has been demonstrated analytically and validated through simulation results. This issue has resulted in a low heat transfer capacity in the circulation loop. To increase the heat transfer capacity, one has to improve this efficiency. To meet such a need, a novel efficiency booster has been developed in this paper. The booster essentially increases the flow driving force and hence significantly improves the overall heat transfer capacity. Design and analysis of this booster have been performed in detail. The performance has been examined through extensive computer simulations. It is concluded that the booster can indeed drastically improve the heat transfer capacity of the natural circulation loop.

An efficiency booster for energy conversion in natural circulation loops

International Nuclear Information System (INIS)

Wang, Dongqing; Jiang, Jin

2016-01-01

Highlights: • Low driving power conversion efficiency of natural circulation loops is proved. • The low conversion efficiency leads to low heat transfer capacity of such loops. • An efficiency booster is designed with turbine to increase the efficiency. • Performance of the proposed booster has been numerically simulated. • The booster drastically enhances heat transfer capacity of such loops. - Abstract: In this paper, the capacity of a natural circulation loop for transferring heat from a heat source to a heat sink has been analyzed. It is concluded that the capacity of the natural circulation loop depends on the conversion efficiency of the thermal energy from the heat source to the driving force for the circulation of the flow. The low conversion efficiency leading to weak driving force in such loops has been demonstrated analytically and validated through simulation results. This issue has resulted in a low heat transfer capacity in the circulation loop. To increase the heat transfer capacity, one has to improve this efficiency. To meet such a need, a novel efficiency booster has been developed in this paper. The booster essentially increases the flow driving force and hence significantly improves the overall heat transfer capacity. Design and analysis of this booster have been performed in detail. The performance has been examined through extensive computer simulations. It is concluded that the booster can indeed drastically improve the heat transfer capacity of the natural circulation loop.

New beam instrumentation in the AGS Booster

International Nuclear Information System (INIS)

Witkover, R.L.

1991-01-01

The AGS Booster was designed to accelerate beams from 2x10 10 polarized protons to 1.5x10 13 protons and heavy ions through Au +33 . The range of beam parameters and the high vacuum, and radiation environment presented challenges for the beam instrumentation. Some interesting beam monitors in the Booster and transport lines, will be described. Where available, results will be presented. 21 refs., 7 figs

Accelerating RF cavity of the Booster

CERN Multimedia

CERN PhotoLab

1981-01-01

Each of the 4 PS Booster rings has a single accelerating cavity. It consists of 2 quarter-wave ferrite-loaded resonators. There are 2 figure-of-eight loops on the ferrite loads for tuning the frequency throughout the acceleration cycle, from 3 to 8 MHz (from 50 MeV at injection to the original Booster energy of 800 MeV, 2 GeV today). The cavities have a flat design, to fit the ring-to-ring distance of 36 cm. The tube for forced-air cooling is visible in the left front. See also 8301084.

Accelerating RF cavity of the Booster

CERN Multimedia

CERN PhotoLab

1983-01-01

Each of the 4 PS Booster rings has a single accelerating cavity.It consists of 2 quarter-wave ferrite-loaded resonators. 2 figure-of-eight loops tune the frequency throughout the accelerating cycle, from 3 to 8 MHz (from 50 MeV at injection to the original Booster energy of 800 MeV, 2 GeV today). The cavities have a flat design, to fit the ring-to-ring distance of 36 cm, and are forced-air cooled. The 2 round objects in the front-compartments are the final-stage power-tetrodes. See also 8111095.

Weak Depolarizing Resonances in the 3-TeV VLHC Booster

International Nuclear Information System (INIS)

Anferov, V.A.

1999-01-01

The possibility of polarized-proton-beam acceleration in the proposed low-field 3-TeV VLHC booster is considered. We find that the low-field combined function magnets in the booster's long FODO cells cause an inadvertent cancellation of most depolarizing fields due to a mechanism suggested earlier by Chao and Derbenev [Part.Accel.36, 25 (1991)]. The strongest spin-depolarizing resonances in the 3-TeV booster seem to be similar in strength to those in the 250-GeV RHIC. Moreover, the strength of the 3-TeV booster's strongest intrinsic depolarizing resonances decreases with energy, in contrast with the energy growth of the depolarizing resonance's strength in most proton synchrotrons. copyright 1999 The American Physical Society

Diamond Light Source Booster fast orbit feedback system

International Nuclear Information System (INIS)

Gayadeen, S.; Duncan, S.R.; Christou, C.; Heron, M.T.; Rowland, J.

2012-01-01

The Fast Orbit Feedback system that has been installed on the Diamond Light Source Storage ring has been replicated on the Booster synchrotron in order to provide a test bed for the development of the Storage Ring controller design. To realise this the Booster is operated in DC mode. The electron beam is regulated in two planes using the Fast Orbit Feedback system, which takes the beam position from 22 beam position monitors for each plane, and calculates offsets to 44 corrector power supplies at a sample rate of 10 kHz. This paper describes the design and realization of the controller for the Booster Fast Orbit Feedback, presents results from the implementation and considers future development

New beam instrumentation in the AGS Booster

Energy Technology Data Exchange (ETDEWEB)

Witkover, R.L.

1991-01-01

The AGS Booster was designed to accelerate beams from 2{times}10{sup 10} polarized protons to 1.5{times}10{sup 13} protons and heavy ions through Au{sup +33}. The range of beam parameters and the high vacuum, and radiation environment presented challenges for the beam instrumentation. Some interesting beam monitors in the Booster and transport lines, will be described. Where available, results will be presented. 21 refs., 7 figs.

Performance evaluation of DAAF as a booster material using the onionskin test

Energy Technology Data Exchange (ETDEWEB)

Morris, John S [Los Alamos National Laboratory; Francois, Elizabeth G [Los Alamos National Laboratory; Hooks, Daniel E [Los Alamos National Laboratory; Hill, Larry G [Los Alamos National Laboratory; Harry, Herbert H [Los Alamos National Laboratory

2010-12-02

Initiation of insensitive high explosive (IHE) formulations requires the use of a booster explosive in the initiation train. Booster material selection is crucial, as the initiation must reliably function across some spectrum of physical parameters. The interest in Diaminoazoxyfurazan (DAAF) for this application stems from the fact that it possesses many traits of an IHE but is shock sensitive enough to serve as an explosive booster. A hemispherical wave breakout test, termed the onionskin test, is one of the methods used to evaluate the performance of a booster material. The wave breakout time-position history at the surface of a hemispherical IHE charge is recorded and the relative uniformity of the breakout can be quantitatively compared between booster materials. A series of onionskin tests were performed to investigate breakout and propagation diaminoazoxyfurazan (DAAF) at low temperatures to evaluate ignition and detonation spreading in comparison to other explosives commonly used in booster applications. Some wave perturbation was observed with the DAAF booster in the onionskin tests presented. The results of these tests will be presented and discussed.

Design study of the large hadron electron collider and a rapid cycling synchrotron as alternative to the PS booster upgrade at CERN

International Nuclear Information System (INIS)

Fitterer, Miriam

2013-01-01

With the Large Hadron Collider (LHC) the exploration of particle physics at center of mass energies at the TeV scale has begun. To extend the discovery potential of the LHC, a major upgrade is foreseen around 2020 of the LHC itself and the LHC injectors - the chain of accelerators preparing the beam for the LHC. One of the injectors - the second one in the chain - is the Proton Synchrotron (PS) Booster. Its performance is currently limited by the space-charge effect, which is the effect of the electromagnetic field of the particle beam on itself. This effect becomes weaker with higher energy, and therefore an energy upgrade of the PS Booster to 2 GeV maximum beam energy is foreseen. As the PS Booster is with its 40 years already an old machine, the construction of a new accelerator, a Rapid Cycling Synchrotron (RCS), to replace the PS Booster has been proposed. In this thesis different options for the beam guidance in the RCS - referred to as lattice and optics - are studied, followed by a more general comparison of different lattices and optics and their performance under consideration of the space-charge effect. To further complement the LHC physics program, also the possibility of deep inelastic lepton-nucleon scattering at the LHC has been suggested, referred to as Large Hadron Electron Collider (LHeC). In this case the proton beam of the LHC collides with the electron beam, which is accelerated in a separate newly built machine. Two options are considered as electron accelerator: a new energy recovery linac - the Linac-Ring option - and the installation of an electron ring in the existing LHC tunnel - the Ring-Ring option. One of the main challenges of the Ring-Ring option is the integration of the electron ring in the current LHC tunnel. A layout, lattice and optics of the electron accelerator is developed in this thesis, which meets the requirements with regard to integration and reaches the beam parameters demanded by the particle physics experiments.

Design study of the large hadron electron collider and a rapid cycling synchrotron as alternative to the PS booster upgrade at CERN

Energy Technology Data Exchange (ETDEWEB)

Fitterer, Miriam

2013-02-22

With the Large Hadron Collider (LHC) the exploration of particle physics at center of mass energies at the TeV scale has begun. To extend the discovery potential of the LHC, a major upgrade is foreseen around 2020 of the LHC itself and the LHC injectors - the chain of accelerators preparing the beam for the LHC. One of the injectors - the second one in the chain - is the Proton Synchrotron (PS) Booster. Its performance is currently limited by the space-charge effect, which is the effect of the electromagnetic field of the particle beam on itself. This effect becomes weaker with higher energy, and therefore an energy upgrade of the PS Booster to 2 GeV maximum beam energy is foreseen. As the PS Booster is with its 40 years already an old machine, the construction of a new accelerator, a Rapid Cycling Synchrotron (RCS), to replace the PS Booster has been proposed. In this thesis different options for the beam guidance in the RCS - referred to as lattice and optics - are studied, followed by a more general comparison of different lattices and optics and their performance under consideration of the space-charge effect. To further complement the LHC physics program, also the possibility of deep inelastic lepton-nucleon scattering at the LHC has been suggested, referred to as Large Hadron Electron Collider (LHeC). In this case the proton beam of the LHC collides with the electron beam, which is accelerated in a separate newly built machine. Two options are considered as electron accelerator: a new energy recovery linac - the Linac-Ring option - and the installation of an electron ring in the existing LHC tunnel - the Ring-Ring option. One of the main challenges of the Ring-Ring option is the integration of the electron ring in the current LHC tunnel. A layout, lattice and optics of the electron accelerator is developed in this thesis, which meets the requirements with regard to integration and reaches the beam parameters demanded by the particle physics experiments.

Booster Main Engine Selection Criteria for the Liquid Fly-Back Booster

Science.gov (United States)

Ryan, Richard M.; Rothschild, William J.; Christensen, David L.

1998-01-01

The Liquid Fly-Back Booster (LFBB) Program seeks to enhance the Space Shuttle system safety performance and economy of operations through the use of an advanced, liquid propellant Booster Main Engine (BME). There are several viable BME candidates that could be suitable for this application. The objective of this study was to identify the key criteria to be applied in selecting among these BME candidates. This study involved an assessment of influences on the overall LFBB utility due to variations in the candidate rocket engines' characteristics. This includes BME impacts on vehicle system weight, perfortnance,design approaches, abort modes, margins of safety, engine-out operations, and maintenance and support concepts. Systems engineering analyses and trade studies were performed to identify the LFBB system level sensitivities to a wide variety of BME related parameters. This presentation summarizes these trade studies and the resulting findings of the LFBB design teams regarding the BME characteristics that most significantly affect the LFBB system. The resulting BME choice should offer the best combination of reliability, performance, reusability, robustness, cost, and risk for the LFBB program.

Space Launch System Accelerated Booster Development Cycle

Science.gov (United States)

Arockiam, Nicole; Whittecar, William; Edwards, Stephen

2012-01-01

With the retirement of the Space Shuttle, NASA is seeking to reinvigorate the national space program and recapture the public s interest in human space exploration by developing missions to the Moon, near-earth asteroids, Lagrange points, Mars, and beyond. The would-be successor to the Space Shuttle, NASA s Constellation Program, planned to take humans back to the Moon by 2020, but due to budgetary constraints was cancelled in 2010 in search of a more "affordable, sustainable, and realistic" concept2. Following a number of studies, the much anticipated Space Launch System (SLS) was unveiled in September of 2011. The SLS core architecture consists of a cryogenic first stage with five Space Shuttle Main Engines (SSMEs), and a cryogenic second stage using a new J-2X engine3. The baseline configuration employs two 5-segment solid rocket boosters to achieve a 70 metric ton payload capability, but a new, more capable booster system will be required to attain the goal of 130 metric tons to orbit. To this end, NASA s Marshall Space Flight Center recently released a NASA Research Announcement (NRA) entitled "Space Launch System (SLS) Advanced Booster Engineering Demonstration and/or Risk Reduction." The increased emphasis on affordability is evident in the language used in the NRA, which is focused on risk reduction "leading to an affordable Advanced Booster that meets the evolved capabilities of SLS" and "enabling competition" to "enhance SLS affordability. The purpose of the work presented in this paper is to perform an independent assessment of the elements that make up an affordable and realistic path forward for the SLS booster system, utilizing advanced design methods and technology evaluation techniques. The goal is to identify elements that will enable a more sustainable development program by exploring the trade space of heavy lift booster systems and focusing on affordability, operability, and reliability at the system and subsystem levels5. For this study

Booster parameter list

International Nuclear Information System (INIS)

Parsa, Z.

1986-10-01

The AGS Booster is designed to be an intermediate synchrotron injector for the AGS, capable of accelerating protons from 200 MeV to 1.5 GeV. The parameters listed include beam and operational parameters and lattice parameters, as well as parameters pertaining to the accelerator's magnets, vacuum system, radio frequency acceleration system, and the tunnel. 60 refs., 41 figs

Mathematical modeling of compression processes in air-driven boosters

International Nuclear Information System (INIS)

Li Zeyu; Zhao Yuanyang; Li Liansheng; Shu Pengcheng

2007-01-01

The compressed air in normal pressure is used as the source of power of the air-driven booster. The continuous working of air-driven boosters relies on the difference of surface area between driven piston and driving piston, i.e., the different forces acting on the pistons. When the working surface area of the driving piston for providing power is greater than that of the driven piston for compressing gas, the gas in compression chamber will be compressed. On the basis of the first law of thermodynamics, the motion regulation of piston is analyzed and the mathematical model of compression processes is set up. Giving a calculating example, the vary trends of gas pressure and pistons' move in working process of booster have been gotten. The change of parameters at different working conditions is also calculated and compared. And the corresponding results can be referred in the design of air-driven boosters

Booster fans : some considerations for their usage in underground coal mines

Energy Technology Data Exchange (ETDEWEB)

Gillies, S.; Slaughter, C. [Missouri Univ. of Science and Technology, Rolla, MO (United States); Calizaya, F. [Utah Univ., Salt Lake City, UT (United States); Wu, H.W. [Gillies Wu Mining Technology Pty Ltd., Brisbane, QLD (Australia)

2010-07-01

This paper reported on a study that investigated the conditions under which booster fans can be used safely and efficiently in underground coal mines. Booster fans are installed in series with a main surface fan and are used to boost the air pressure of the ventilation air passing through it. Several coal mining countries use booster fans, but in the United States, they are only used in metal/non-metal mines due to concerns of uncontrolled recirculation. This study investigated installations of booster fans in non-US underground coal mines where safe and efficient atmospheric conditions are achieved. The purpose was to collect reliable information on airway resistances and flow requirements typical in large US coal mines. The study showed that safe booster fan installations are found in both high and low gas conditions, and sometimes where workings are located at great depths. The interlocking systems within the booster fan can control the underground fans and avoid recirculation when surface fans are unexpectedly turned off. Another purpose of the study was to determine when booster fans become a more viable solution in coal mines due to increases in air requirements at higher production rates. It was concluded that a new fan selection algorithm to produce recirculation-free ventilation designs will be developed to enable US coal mine operators to develop ventilation designs to extract coal seams from depths greater than 1000 m. 17 refs., 1 fig.

Ram booster

Science.gov (United States)

Brand, Vance D. (Inventor); Morgan, Walter Ray (Inventor)

2011-01-01

The present invention is a space launch system and method to propel a payload bearing craft into earth orbit. The invention has two, or preferably, three stages. The upper stage has rocket engines capable of carrying a payload to orbit and provides the capability of releasably attaching to the lower, or preferably, middle stage. Similar to the lower stage, the middle stage is a reusable booster stage that employs all air breathing engines, is recoverable, and can be turned-around in a short time between missions.

Proposed data acquisition system for the Fermilab Booster

International Nuclear Information System (INIS)

Bharadwaj, V.; Peggs, S.; Wu, G.; Saltmarsh, C.

1991-01-01

At present, studies involving the FNAL Booster (or in fact most accelerators) depend on knowing exactly what detector one has to look at and at what time. Because of this, most studies are done 'on-line' and involve looking for repetitive effects using a limited number of detectors. In this paper the authors propose to design a Booster Data Acquisition System (BDAQ) for the FNAL Booster. In essence this system consists of a large number of digitizers with circular memory buffers. After a machine cycle of interest, these buffers are frozen and then read out into a mass storage device. This paper discusses the hardware and software capabilities needed to make such a data acquisition system a powerful tool for doing accelerator physics studies and improving machine performance

Injection Bucket Jitter Compensation Using Phase Lock System at Fermilab Booster

Energy Technology Data Exchange (ETDEWEB)

Seiya, K. [Fermilab; Drennan, C. [Fermilab; Pellico, W. [Fermilab; Chaurize, S. [Fermilab

2017-05-12

The extraction bucket position in the Fermilab Booster is controlled with a cogging process that involves the comparison of the Booster rf count and the Recycler Ring revolution marker. A one rf bucket jitter in the ex-traction bucket position results from the variability of the process that phase matches the Booster to the Recycler. However, the new slow phase lock process used to lock the frequency and phase of the Booster rf to the Recycler rf has been made digital and programmable and has been modified to correct the extraction notch position. The beam loss at the Recycler injection has been reduced by 20%. Beam studies and the phase lock system will be discussed in this paper.

Logic and control module for the Fermilab booster beam damper

International Nuclear Information System (INIS)

Sandberg, B.R.

1977-01-01

A logic and control module is included in the electronic system of the booster superdamper. This module produces a 9-bit digital word that controls the delay of beam bunch position information in the Fermilab booster synchrotron so that it arrives at the damping electrodes at the same time as the bunch of beam to be corrected. This delay word generator also has an output feature that only allows delay time decreases as the booster synchrotron frequency program increases monotonically. Such a feature guards against low-index incidental FM from affecting the delay computations

Identifying strategies to improve the effectiveness of booster seat laws

Science.gov (United States)

2008-05-01

The objective of this project was to identify strategies to improve the effectiveness of booster seat laws. The project explored the possible factors that relate to the use and nonuse of booster seats, and examined the attitudes of law enforcement of...

The Booster to AGS beam transfer fast kicker systems

International Nuclear Information System (INIS)

Zhang, W.; Bunicci, J.; Soukas, A.V.; Zhang, S.Y.

1992-01-01

The Brookhaven AGS Booster has a very successful commissioning period in June 1991. The third phase of that commissioning was a beam extraction test. The Booster extraction fast kicker (F3) deflected a 1.2 GeV proton beam from the Booster circulating orbit into the extraction septum aperture, partially down the extraction line to a temporary beam stop. Now, the Booster is committed to the AGS operations program for both heavy ion and proton beams. Thus, the Booster extraction and the corresponding AGS injection systems must operate routinely up to a pulse repetition frequency of 7.5 Hertz, and up to a beam energy of 1.5 Gev. The injection fast kicker is located in the A5 section of the AGS ring and is used to deflect the proton or heavy ion beam into its final AGS closed orbit. A distinctive feature of the AGS injection fast kicker modulators is the tail-bitting function required for proton beam injection. This enables the system to produce a fast current fall time to go along with the high current pulse amplitude with a fast rise time. The AGS injection fast kicker system has three pulse modulators, and each modulator consists of two thyratrons. The main PFN thyratrons switch on the current, and the tail bitting thyratrons are used to force the magnet current to decrease rapidly. Two digital pulse delay generators are used to align the main thyratrons and the tail bitting thyratrons respectively. The system has been tested and installed. The final commissioning of the Booster to AGS beam transfer line and injection is currently being undertaken. In this article, the system design, realization techniques and performance data will be presented

A rookie's guide to Booster operations. Booster technical note no. 231

Energy Technology Data Exchange (ETDEWEB)

Zeno, K. [Brookhaven National Lab. (BNL), Upton, NY (United States). Alternating Gradient Synchrotron Dept.

1998-09-29

The purpose of the Booster is to act as an injector for the AGS. It accelerates both protons and other ions. Proton acceleration is distinguished from the acceleration of other ions for several reasons. First, the experimental physics associated with protons, called High Energy Physics is different than that associated with other Ions, called Heavy Ion Physics. From the machine perspective, the process of injection of so called Heavy Ions (ions which are not protons), is distinctly different, from that of protons. A different preinjector, or injector for the Booster, is used for each case. For Protons, a 200 MeV Linear accelerator (The Linac) serves as a preinjector; for Heavy Ions, the Tandem Van De Graaf (The Tandem) is the preinjector. An attribute of the circulating beam which determines to a large degree what problems and what type of machine setup is involved is the beam intensity. The author's focus in this guide is on trying to convey the knowledge and experience involved in the operation of the Booster. Many of the problems encountered can be traced back to equipment failures, often power supplies. Although diagnostics are used, there can also be issues with the controls system itself. Problems with the controls system and prevent fixing or even finding a problem with a machine. The issue of improving a machines' performance can often involve trial and error and observations. The hard part is finding the relationships between things in the day to day operation of the machine. Abstractions about physics, information about controls and instrumentation, and purely empirical observations of how the machine behaves are all part of it.

Momentum Cogging at the Fermilab Booster

International Nuclear Information System (INIS)

Seiya, K.; Drennan, C.C.; Pellico, W.; Triplett, A.K.; Waller, A.M.

2012-01-01

The Fermilab Booster has an upgrade plan called the Proton Improvement Plan (PIP). The flux throughput goal is 2E17 protons/hour which, is almost double the present flux, 1.1E17 protons/hour. The beam loss in the machine is going to be an issue. The Booster accelerates beam from 400 MeV to 8 GeV and extracts to the Main Injector (MI). The current cogging process synchronizes the extraction kicker gap to the MI by changing radial position of the beam during the cycle. The gap creation occurs at about 700 MeV, which is about 6 ms into the cycle. The cycle-to-cycle variations of the Booster are larger at lower energy. However, changing the radial position at low energy for cogging is limited because of aperture. Momentum cogging is able to move the gap creation to an earlier time by using dipole correctors and radial position feedback, and is able to control the revolution frequency and radial position at the same time. The new cogging is expected to reduce beam loss and not be limited by aperture. The progress of the momentum cogging system development is going to be discussed in this paper.

FNAL Booster intensity, extraction, and synchronization control for collider operation

International Nuclear Information System (INIS)

Ducar, R.J.; Lackey, J.R.; Tawzer, S.R.

1987-03-01

Booster operation for collider physics is considerably different than for fixed target operation. Various scenarios for collider physics, machine studies, and P-Bar targeting may require that the intensity vary from 5E10 PPP to 3E12 PPP at a 15 Hertz machine cycle rate. In addition to the normal Booster single turn extraction mode, collider operations require that the Booster inject into the Main Ring a small number of beam bunches for coalescing into a single high intensity bunch. These bunches must be synchronized such that the center bunch arrives in the RF bucket which corresponds to the zero phase of the coalescing cavity. The system implemented has the ability to deliver a precise fraction of the available 84 Booster beam bunches to Main Ring or to the P-Bar Debuncher via the newly installed AP-4 beam line for tune-up and studies. It is required that all of the various intensity and extraction scenarios be accommodated with minimal operator intervention

Space shuttle with common fuel tank for liquid rocket booster and main engines (supertanker space shuttle)

Science.gov (United States)

Thorpe, Douglas G.

1991-01-01

An operation and schedule enhancement is shown that replaces the four-body cluster (Space Shuttle Orbiter (SSO), external tank, and two solid rocket boosters) with a simpler two-body cluster (SSO and liquid rocket booster/external tank). At staging velocity, the booster unit (liquid-fueled booster engines and vehicle support structure) is jettisoned while the remaining SSO and supertank continues on to orbit. The simpler two-bodied cluster reduces the processing and stack time until SSO mate from 57 days (for the solid rocket booster) to 20 days (for the liquid rocket booster). The areas in which liquid booster systems are superior to solid rocket boosters are discussed. Alternative and future generation vehicles are reviewed to reveal greater performance and operations enhancements with more modifications to the current methods of propulsion design philosophy, e.g., combined cycle engines, and concentric propellant tanks.

Linac boosters for electrostatic machines

International Nuclear Information System (INIS)

Ben-Zvi, I.; Brookhaven National Lab., Upton, NY

1990-01-01

A survey of linacs which are used as boosters to electrostatic accelerators is presented. Machines both operating and under construction, copper and superconducting, are reviewed. The review includes data on the accelerating structures, performance, rf and control, beam optics, budget, vacuum and cryogenics. (orig.)

Dynamical stability of slip-stacking particles

Energy Technology Data Exchange (ETDEWEB)

Eldred, Jeffrey; Zwaska, Robert

2014-09-01

We study the stability of particles in slip-stacking configuration, used to nearly double proton beam intensity at Fermilab. We introduce universal area factors to calculate the available phase space area for any set of beam parameters without individual simulation. We find perturbative solutions for stable particle trajectories. We establish Booster beam quality requirements to achieve 97% slip-stacking efficiency. We show that slip-stacking dynamics directly correspond to the driven pendulum and to the system of two standing-wave traps moving with respect to each other.

JAERI tandem-accelerator and tandem-booster

Energy Technology Data Exchange (ETDEWEB)

Yoshida, Tadashi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

1998-03-01

In 1982, aiming at the new development of atomic energy research, the tandem accelerator of Japan Atomic Energy Research Institute (JAERI) was installed. In fiscal year 1993, the superconducting boosters which can increase the ion energy by up to 4 times were added, and the research in the region below 1000 MeV became possible. Those are electrostatic type accelerators which are easy to be used especially in basic research field, and are useful for future research. The tandem accelerator has been operated while maintaining the first class performance as the accelerator for various kinds of heavy ion beam. It has the special shape among electrostatic type accelerators, and is excellent in the easiness of control and stability. The main particulars of the tandem accelerator are shown. As for the ion sources of the tandem accelerator, three cesium sputter type ion sources are installed on two high voltage stands. The kinds of the ions which can be accelerated are mainly negative ions. As the improvement, electron cyclotron resonance (ECR) ion sources are expected to be adopted. As for the tandem boosters, the 1/4 wavelength type resonance hollow cylinder was adopted. The constitution of the tandem boosters is explained. The way of utilizing the tandem accelerator system and the aim for hereafter are reported. (K.I.)

47 CFR 74.1290 - FM translator and booster station information available on the Internet.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 4 2010-10-01 2010-10-01 false FM translator and booster station information... DISTRIBUTIONAL SERVICES FM Broadcast Translator Stations and FM Broadcast Booster Stations § 74.1290 FM translator and booster station information available on the Internet. The Media Bureau's Audio Division...

78 FR 29062 - Signal Booster Rules

Science.gov (United States)

2013-05-17

... number of FCC rules concerning signal boosters for consumer and industrial use. This document corrects a... chapter; the Maritime Services (ship earth station devices only) pursuant to part 80 of this chapter; and...

Advanced Booster Composite Case/Polybenzimidazole Nitrile Butadiene Rubber Insulation Development

Science.gov (United States)

Gentz, Steve; Taylor, Robert; Nettles, Mindy

2015-01-01

The NASA Engineering and Safety Center (NESC) was requested to examine processing sensitivities (e.g., cure temperature control/variance, debonds, density variations) of polybenzimidazole nitrile butadiene rubber (PBI-NBR) insulation, case fiber, and resin systems and to evaluate nondestructive evaluation (NDE) and damage tolerance methods/models required to support human-rated composite motor cases. The proposed use of composite motor cases in Blocks IA and II was expected to increase performance capability through optimizing operating pressure and increasing propellant mass fraction. This assessment was to support the evaluation of risk reduction for large booster component development/fabrication, NDE of low mass-to-strength ratio material structures, and solid booster propellant formulation as requested in the Space Launch System NASA Research Announcement for Advanced Booster Engineering Demonstration and/or Risk Reduction. Composite case materials and high-energy propellants represent an enabling capability in the Agency's ability to provide affordable, high-performing advanced booster concepts. The NESC team was requested to provide an assessment of co- and multiple-cure processing of composite case and PBI-NBR insulation materials and evaluation of high-energy propellant formulations.

MEASUREMENTS AND MODELING OF EDDY CURRENT EFFECTS IN BNL'S AGS BOOSTER

International Nuclear Information System (INIS)

BROWN, K.A.; AHRENS, L.; GARDNER, C.; GLENN, J.W.; HARVEY, M.; MENG, W.; ZENO, K.

2006-01-01

Recent beam experiments at BNL's AGS Booster have enabled us to study in more detail the effects of eddy currents on the lattice structure and our control over the betatron tune. The Booster is capable of operating at ramp rates as high as 9 T/sec. At these ramp rates eddy currents in the vacuum chambers significantly alter the fields and gradients seen by the beam as it is accelerated. The Booster was designed with these effects in mind and to help control the field uniformity and linearity in the Booster Dipoles special vacuum chambers were designed with current windings to negate the affect of the induced eddy currents. In this report results from betatron tune measurements and eddy current simulations will be presented. We will then present results from modeling the accelerator using the results of the magnetic field simulations and compare these to the measurements

Tdap Booster Requirements for Secondary Schools

Science.gov (United States)

... Experts State Information Tdap booster requirements for secondary schools State Td or Tdap Mandate for Sec School ... Checklists Standing Orders Storage & Handling Talking with Parents Temperature Logs Top Handouts Translations Vaccine Index >> view all ...

Injection and transfer lines of the PS Booster

CERN Multimedia

Photographic Service

1972-01-01

In the foreground is the vacuum chamber for the 50 MeV proton beam coming from the Linac. The tank held by white frames houses the "Vertical Distributor", which deflects the Linac beam to the levels of the Booster's 4 superposed rings. After acceleration in the Booster, originally to 800 MeV, today to 1.4 GeV, the beams from the 4 rings are combined in the vertical plane and transfered to the 26 GeV PS. The "Recombination Line", intersecting the injection line, crosses the picture from left to right.

Design study of CEPC Alternating Magnetic Field Booster

CERN Document Server

Bian, T; Cai, Y; Cui, X; Gao, J; Koratzinos, M; Su, F; Wang, D; Wang, Y; Xiao, M; Zhang, C

2017-01-01

The CEPC is a next generation circular e+e- collider proposed by China. The design of the full energy booster ring of the CEPC is especially challenging. The ejected beam energy is 120 GeV, but that of the injected beam is only 6 GeV. In a conventional approach, the low magnetic field of the main dipole magnets creates problems. We propose operating the booster ring as a large wiggler at low beam energies and as a normal ring at high energies to avoid the problem of very low dipole magnet fields.

Emittance measurement and modeling for the Fermilab Booster

Directory of Open Access Journals (Sweden)

Xiaobiao Huang

2006-01-01

Full Text Available Turn-by-turn beam profile data measured at the Fermilab Booster are studied. Lattice models with experimental accelerator ramping parameters are used to obtain the lattice functions for data analysis. We studied the horizontal and vertical emittance growth behavior in different stages of a booster ramping cycle and its relation to the beam intensity. The transverse and longitudinal components in the horizontal beam width are separated by a fitting model which makes use of the different scaling rules of the beam momentum. We analyze the post-transition horizontal beam size oscillation based on a model where the longitudinal phase-space mismatch has resulted from rf voltage mismatch during the transition-energy crossing. We carried out systematic multiparticle simulation to show that the source of the vertical emittance growth is a combination of the random errors in skew-quadrupole and dipole fields, and the systematic Montague resonance. The effect of random quadrupole field is small for the Fermilab Booster because the betatron envelope tunes are reasonably far away from the half-integer stop band.

76 FR 11680 - Digital Low Power Television, Television Translator, and Television Booster Stations and Digital...

Science.gov (United States)

2011-03-03

...] Digital Low Power Television, Television Translator, and Television Booster Stations and Digital Class A... Commission's Rules to Establish Rules for Digital Low Power, Television Translator, and Television Booster... Digital Low Power Television Translator, Television Booster Stations, and to Amend Rules for Digital Class...

NASA's Space Launch System: Developing the World's Most Powerful Solid Booster

Science.gov (United States)

Priskos, Alex

2016-01-01

NASA's Journey to Mars has begun. Indicative of that challenge, this will be a multi-decadal effort requiring the development of technology, operational capability, and experience. The first steps are under way with more than 15 years of continuous human operations aboard the International Space Station (ISS) and development of commercial cargo and crew transportation capabilities. NASA is making progress on the transportation required for deep space exploration - the Orion crew spacecraft and the Space Launch System (SLS) heavy-lift rocket that will launch Orion and large components such as in-space stages, habitat modules, landers, and other hardware necessary for deep-space operations. SLS is a key enabling capability and is designed to evolve with mission requirements. The initial configuration of SLS - Block 1 - will be capable of launching more than 70 metric tons (t) of payload into low Earth orbit, greater mass than any other launch vehicle in existence. By enhancing the propulsion elements and larger payload fairings, future SLS variants will launch 130 t into space, an unprecedented capability that simplifies hardware design and in-space operations, reduces travel times, and enhances the odds of mission success. SLS will be powered by four liquid fuel RS-25 engines and two solid propellant five-segment boosters, both based on space shuttle technologies. This paper will focus on development of the booster, which will provide more than 75 percent of total vehicle thrust at liftoff. Each booster is more than 17 stories tall, 3.6 meters (m) in diameter and weighs 725,000 kilograms (kg). While the SLS booster appears similar to the shuttle booster, it incorporates several changes. The additional propellant segment provides additional booster performance. Parachutes and other hardware associated with recovery operations have been deleted and the booster designated as expendable for affordability reasons. The new motor incorporates new avionics, new propellant

Beam Based RF Voltage Measurements and Longitudinal Beam Tomography at the Fermilab Booster

Energy Technology Data Exchange (ETDEWEB)

Bhat, C. M. [Fermilab; Bhat, S. [Fermilab

2017-10-19

Increasing proton beam power on neutrino production targets is one of the major goals of the Fermilab long term accelerator programs. In this effort, the Fermilab 8 GeV Booster synchrotron plays a critical role for at least the next two decades. Therefore, understanding the Booster in great detail is important as we continue to improve its performance. For example, it is important to know accurately the available RF power in the Booster by carrying out beam-based measurements in order to specify the needed upgrades to the Booster RF system. Since the Booster magnetic field is changing continuously measuring/calibrating the RF voltage is not a trivial task. Here, we present a beam based method for the RF voltage measurements. Data analysis is carried out using computer programs developed in Python and MATLAB. The method presented here is applicable to any RCS which do not have flat-bottom and flat-top in the acceleration magnetic ramps. We have also carried out longitudinal beam tomography at injection and extraction energies with the data used for RF voltage measurements. Beam based RF voltage measurements and beam tomography were never done before for the Fermilab Booster. The results from these investigations will be very useful in future intensity upgrades.

Thermoeconomic model of a commercial transcritical booster refrigeration system

DEFF Research Database (Denmark)

Ommen, Torben Schmidt; Elmegaard, Brian

2011-01-01

For cooling applications in supermarkets, booster refrigeration systems operating in both transcritical and subcritical conditions are increasingly used. A thermodynamic model of a transcritical booster refrigeration plant is tailored to match the new generation of commercial refrigeration plants...... of exergy for cooling. Second law analysis is needed to illustrate the characteristics of the plant at different load rates, according to the alternating load profile and corresponding to outdoor conditions. With the detailed model, different uses of the analysis are possible, including thermoeconomic...

Numerically controlled oscillator for the Fermilab Booster

International Nuclear Information System (INIS)

Crisp, J.L.; Ducar, R.J.

1989-01-01

In order to improve the stability of the Fermilab Booster low level rf system, a numerically controlled oscillator system is being constructed. Although the system has not been implemented to date, the design is outlined in this paper. The heart of the new system consists of a numerically synthesized frequency generator manufactured by the Sciteq Company. The 3 GHz/sec rate and 30 to 53 MHz range of the Booster frequency program required the design of a CAMAC based, fast-cycling (1 MHz), 65K x 32 bit, digital function generator. A 1 MHz digital adder and 12 bit analog to digital converter will be used to correct small program errors by phase locking the oscillator to the beam. 6 refs., 1 fig

The operational status of the Booster injector for the AGS accelerator complex at BNL

International Nuclear Information System (INIS)

Ahrens, L.; Bleser, E.; Brennan, J.M.; Gardner, C.; Gill, E.; Glenn, J.W.; Reece, K.; Roser, T.; van Asselt, W.; Weng, W.T.

1992-01-01

The Booster synchrotron at Brookhaven National Laboratory has been incorporated into the accelerator chain at the Alternating Gradient Synchrotron (AGS) complex. After a successful first commissioning effort in the spring of 1991, the Booster has been part of this year's silicon, gold and proton physics runs. After a brief review of the Booster design goals, and of the early commissioning, this paper will summarize this year's activities

Internal Flow Simulation of Enhanced Performance Solid Rocket Booster for the Space Transportation System

Science.gov (United States)

Ahmad, Rashid A.; McCool, Alex (Technical Monitor)

2001-01-01

An enhanced performance solid rocket booster concept for the space shuttle system has been proposed. The concept booster will have strong commonality with the existing, proven, reliable four-segment Space Shuttle Reusable Solid Rocket Motors (RSRM) with individual component design (nozzle, insulator, etc.) optimized for a five-segment configuration. Increased performance is desirable to further enhance safety/reliability and/or increase payload capability. Performance increase will be achieved by adding a fifth propellant segment to the current four-segment booster and opening the throat to accommodate the increased mass flow while maintaining current pressure levels. One development concept under consideration is the static test of a "standard" RSRM with a fifth propellant segment inserted and appropriate minimum motor modifications. Feasibility studies are being conducted to assess the potential for any significant departure in component performance/loading from the well-characterized RSRM. An area of concern is the aft motor (submerged nozzle inlet, aft dome, etc.) where the altered internal flow resulting from the performance enhancing features (25% increase in mass flow rate, higher Mach numbers, modified subsonic nozzle contour) may result in increased component erosion and char. To assess this issue and to define the minimum design changes required to successfully static test a fifth segment RSRM engineering test motor, internal flow studies have been initiated. Internal aero-thermal environments were quantified in terms of conventional convective heating and discrete phase alumina particle impact/concentration and accretion calculations via Computational Fluid Dynamics (CFD) simulation. Two sets of comparative CFD simulations of the RSRM and the five-segment (IBM) concept motor were conducted with CFD commercial code FLUENT. The first simulation involved a two-dimensional axi-symmetric model of the full motor, initial grain RSRM. The second set of analyses

GRYPHON: Air launched space booster

Science.gov (United States)

1993-06-01

The project chosen for the winter semester Aero 483 class was the design of a next generation Air Launched Space Booster. Based on Orbital Sciences Corporation's Pegasus concept, the goal of Aero 483 was to design a 500,000 pound air launched space booster capable of delivering 17,000 pounds of payload to Low Earth Orbit and 8,000 pounds of payload to Geosynchronous Earth Orbit. The resulting launch vehicle was named the Gryphon. The class of forty senior aerospace engineering students was broken down into eight interdependent groups. Each group was assigned a subsystem or responsibility which then became their field of specialization. Spacecraft Integration was responsible for ensuring compatibility between subsystems. This group kept up to date on subsystem redesigns and informed those parties affected by the changes, monitored the vehicle's overall weight and dimensions, and calculated the mass properties of the booster. This group also performed the cost/profitability analysis of the Gryphon and obtained cost data for competing launch systems. The Mission Analysis Group was assigned the task of determining proper orbits, calculating the vehicle's flight trajectory for those orbits, and determining the aerodynamic characteristics of the vehicle. The Propulsion Group chose the engines that were best suited to the mission. This group also set the staging configurations for those engines and designed the tanks and fuel feed system. The commercial satellite market, dimensions and weights of typical satellites, and method of deploying satellites was determined by the Payloads Group. In addition, Payloads identified possible resupply packages for Space Station Freedom and identified those packages that were compatible with the Gryphon. The guidance, navigation, and control subsystems were designed by the Mission Control Group. This group identified required tracking hardware, communications hardware telemetry systems, and ground sites for the location of the Gryphon

Fiber optics in the BNL Booster radiation environment

International Nuclear Information System (INIS)

Beadle, E.R.

1991-01-01

The Booster instrumentation uses analog and digital fiber optic links, designed to withstand at least 50 krads without performance degradation. The links use inexpensive and commercially available components that operate at a center wavelength of 820 nm. The analog link operates to 30 MHz over a 200 m fiber and can provide insertion gain. The digital link provides 60 ns timing pulses without the dispersive effects of coaxial cables. The optical fiber is a step-index hard clad silica type with a 200 micron core. This paper presents the component selection criteria, link design, installation, testing and performance for the optical links in the Booster instrumentation systems

Booster Applications Facility report, Phase 2

Energy Technology Data Exchange (ETDEWEB)

Thieberger, P. (ed.)

1991-06-01

This report summarizes studies and planning performed by Brookhaven National Laboratory (BNL) personnel at the request of NASA for the design, construction and operation of experimental areas and facilities for utilization of ion beams from the BNL Booster synchrotron particle accelerator. These facilities would be primarily utilized to simulate space radiation for radiobiological research, shielding studies and detector calibrations. The feasibility of such a project has been established, preliminary designs and cost estimates have been developed and a formal proposal can be submitted pending DOE concurrence. The main body of this report consists of the material presented by BNL during the meeting with a NASA appointed Panel on December 10 and 11, 1990. The individual speakers have provided brief summaries of their talks and explanations of their figures. In addition there are two appendices. One, contains detailed discussion of the shared mode of operation and the corresponding beam compatibility tables. The second appendix contains cost estimate details. An executive summary on budgets and schedules has been added, containing possible phased construction and outfitting scenarios and the corresponding expense and commitment profiles as well as new operational cost estimates. Material contained in the executive summary reflects the correction of some errors and new studies performed in response to the NASA Panel suggestions.

Proposal of a beam study in the AGS Booster

International Nuclear Information System (INIS)

Machida, S.; Chen, S.

1991-10-01

IN order to achieve the design luminosity, the Superconducting Super Collider (SSC) parameter choices emphasize the preservation of the transverse emittance requiring in the collider a normalized transverse emittance of 1 π.mm.mrad. A stringent accelerator chain emittance budget must be maintained to achieve the final value. Budgeted emittance specifications for the Low Energy Booster (LEB) include 0.4 π.mm.mrad at injection and ≤ 0.6 π.mm.mrad at extraction. The space-charge tune shift is expected to be more than 0.5 when the rms normalized emittance of 0.4 π.mm.mrad at injection and the total number of particles is 1.1 x 10 12 with 1 x 10 10 particles per bunch. Therefore, it is necessary to cope with a large tune shift and avoid emittance deterioration. We have been studying the beam emittance evolution in the LEB by a multi-particle simulation code with space-charge effects. As reported in the several papers we have obtained from the simulation some new insights into the effects which seem to explain qualitatively a cause of the emittance growth. Even quantitatively, we believe that the simulation can predict the emittance growth as a function of time quite accurately because the code includes most details of the physics processes, such as the adiabatic bunching process and acceleration in the fully 6-D phase space treatment, transverse as well as longitudinal space-charge calculations in a self-consistent manner, and intensity decrease due to particle loss. The purpose of this study is to determine quantitatively the emittance deterioration due to space-charge effects, not to find the maximum current an accelerator could accommodate. Since the charge distribution itself may not remain the same, an accurate measurement of the beam profile is an essential factor of the beam study

Increased persistence of antifouling paint biocides when associated with paint particles

International Nuclear Information System (INIS)

Thomas, K.V.; McHugh, M.; Hilton, M.; Waldock, M.

2003-01-01

Release of biocides associated with paint particles into marinas may increase their persistence in the environment. - Current regulatory risk assessment procedures only assess the impact of antifouling paint biocides that are released through leaching from a painted surface. Hull cleaning activities can lead to particles of antifouling paint containing biocides to enter the environment. Comparative pseudo-first order anaerobic degradation rate constants and half-lives were determined for a selection of common antifouling paint booster biocides, their degradation products, and associated with paint particles. Anaerobic half-lives of <0.5 days were calculated for chlorothalonil, dichlofluanid, and SeaNine 211, between 1 and 3 days for DCPMU and DCPU, between 14 and 35 days for diuron and CPDU, and over 226 days for GS26575 and Irgarol 1051. Increased persistence was observed when the compounds were introduced to sediments associated with antifouling paint particles. When present as antifouling paint particles, an increased half-life of 9.9 days for SeaNine 211 and 1.4 days was calculated for dichlofluanid, no significant degradation was observed for diuron. It is suspected that this is due to much of the biocide being initially bound within the matrix of the paint particle that is slowly released through dissolution processes into the sediment pore water prior to degradation. The release of booster biocides associated with paint particles into marinas has the potential to lead to their accumulation unless activities such as hull cleaning are strictly regulated

Increased persistence of antifouling paint biocides when associated with paint particles

Energy Technology Data Exchange (ETDEWEB)

Thomas, K.V.; McHugh, M.; Hilton, M.; Waldock, M

2003-05-01

Release of biocides associated with paint particles into marinas may increase their persistence in the environment. - Current regulatory risk assessment procedures only assess the impact of antifouling paint biocides that are released through leaching from a painted surface. Hull cleaning activities can lead to particles of antifouling paint containing biocides to enter the environment. Comparative pseudo-first order anaerobic degradation rate constants and half-lives were determined for a selection of common antifouling paint booster biocides, their degradation products, and associated with paint particles. Anaerobic half-lives of <0.5 days were calculated for chlorothalonil, dichlofluanid, and SeaNine 211, between 1 and 3 days for DCPMU and DCPU, between 14 and 35 days for diuron and CPDU, and over 226 days for GS26575 and Irgarol 1051. Increased persistence was observed when the compounds were introduced to sediments associated with antifouling paint particles. When present as antifouling paint particles, an increased half-life of 9.9 days for SeaNine 211 and 1.4 days was calculated for dichlofluanid, no significant degradation was observed for diuron. It is suspected that this is due to much of the biocide being initially bound within the matrix of the paint particle that is slowly released through dissolution processes into the sediment pore water prior to degradation. The release of booster biocides associated with paint particles into marinas has the potential to lead to their accumulation unless activities such as hull cleaning are strictly regulated.

Misuse of booster cushions among children and adults in Shanghai-an observational and attitude study during buckling up.

Science.gov (United States)

Bohman, Katarina; Jorlöv, Sofia; Zhou, Shengqi; Zhao, Cloud; Sui, Bo; Ding, Chengkai

2016-10-02

Traffic crashes are one of the leading causes of fatalities among Chinese children. Booster cushion usage in China is low, and there are no studies showing how a population with limited experience handles booster cushions during buckling up. The purpose of this study was to evaluate the handling of and explore the attitudes toward booster cushions among children, parents, and grandparents in Shanghai. An observational study including a convenience sample of 254 children aged 4-12 years was conducted in 2 passenger cars at a shopping center in Shanghai. Parents, grandparents, or the children themselves buckled up the child on 2 types of booster cushions, a 2-stage integrated booster cushion (IBC) and an aftermarket booster cushion (BC). The test participants were observed during buckling up, first without and then with instructions. The test leaders conducted structured interviews. Ninety-eight percent of the uninstructed participants failed to buckle up without identified misuse on the aftermarket booster cushion and 31% of those uninstructed on the integrated booster cushion. The majority of misuse was severe, including placing the belt behind the arm and the lap belt routing above the guiding loops. Instruction reduced misuse to 58% (BC) and 12% (IBC), respectively, and, in particular, severe misuse. Some misuse was related to limited knowledge of how to buckle up on the booster cushion, and some misuse was intentional in order to reduce discomfort. The participants, both children and adults, reported that they preferred the IBC due to good comfort and convenience. Safety was reported as the main reason for adults using booster cushions in general, whereas children reported comfort as the most important motivation. Education is needed to ensure frequent and correct use of booster cushions in China and to raise safety awareness among children and adults. Furthermore, it is important that the booster cushions offer intuitively correct usage to a population with

YALINA Booster subcritical assembly modeling and analyses

International Nuclear Information System (INIS)

Talamo, A.; Gohar, Y.; Aliberti, G.; Cao, Y.; Zhong, Z.; Kiyavitskaya, H.; Bournos, V.; Fokov, Y.; Routkovskaya, C.; Sadovich, S.

2010-01-01

Full text: Accurate simulation models of the YALINA Booster assembly of the Joint Institute for Power and Nuclear Research (JIPNR)-Sosny, Belarus have been developed by Argonne National Laboratory (ANL) of the USA. YALINA-Booster has coupled zones operating with fast and thermal neutron spectra, which requires a special attention in the modelling process. Three different uranium enrichments of 90%, 36% or 21% were used in the fast zone and 10% uranium enrichment was used in the thermal zone. Two of the most advanced Monte Carlo computer programs have been utilized for the ANL analyses: MCNP of the Los Alamos National Laboratory and MONK of the British Nuclear Fuel Limited and SERCO Assurance. The developed geometrical models for both computer programs modelled all the details of the YALINA Booster facility as described in the technical specifications defined in the International Atomic Energy Agency (IAEA) report without any geometrical approximation or material homogenization. Materials impurities and the measured material densities have been used in the models. The obtained results for the neutron multiplication factors calculated in criticality mode (keff) and in source mode (ksrc) with an external neutron source from the two Monte Carlo programs are very similar. Different external neutron sources have been investigated including californium, deuterium-deuterium (D-D), and deuterium-tritium (D-T) neutron sources. The spatial neutron flux profiles and the neutron spectra in the experimental channels were calculated. In addition, the kinetic parameters were defined including the effective delayed neutron fraction, the prompt neutron lifetime, and the neutron generation time. A new calculation methodology has been developed at ANL to simulate the pulsed neutron source experiments. In this methodology, the MCNP code is used to simulate the detector response from a single pulse of the external neutron source and a C code is used to superimpose the pulse until the

New Pulsed Orbit Bump Magnets for the Fermilab Booster Synchrotron

CERN Document Server

Lackey, James; John, Carson; Kashikhin, Vladimir; Makarov, Alexander; Prebys, Eric

2005-01-01

The beam from the Fermilab Linac is injected onto a bump in the closed orbit of the Booster Synchrotron where a carbon foil strips the electrons from the Linac’s negative ion hydrogen beam. Although the Booster itself runs at 15Hz, heat dissipation in the orbit bump magnets has been one limitation to the fraction of the cycles that can be used for beam. New, 0.28T pulsed window frame dipole magnets have been constructed that will fit into the same space as the old ones, run at the full repetition rate of the Booster, and provide a larger bump to allow a cleaner injection orbit. The new magnets use a high saturation flux density Ni-Zn ferrite in the yoke rather than laminated steel. The presented magnetic design includes two and three dimensional magnetic field calculations with eddy currents and ferrite nonlinear effects.

47 CFR 73.827 - Interference to the input signals of FM translator or FM booster stations.

Science.gov (United States)

2010-10-01

... translator or FM booster stations. 73.827 Section 73.827 Telecommunication FEDERAL COMMUNICATIONS COMMISSION... Interference to the input signals of FM translator or FM booster stations. (a) An authorized LPFM station will not be permitted to continue to operate if an FM translator or FM booster station demonstrates that...

Data acquisition and control of the Zero Gradient Synchrotron 500 MeV booster synchrotron

International Nuclear Information System (INIS)

Timm, R.E.; Forrestal, J.; Hogrefe, R.; Voss, D.

1977-01-01

A data acquisition and control philosophy for the Zero Gradient Synchrotron (ZGS) 500 MeV booster has involved a top down design incorporating all of the systems comprising the booster. Consideration of operational complexity was necessary because the booster is to be used simultaneously for ZGS injection, and solid state physics studies. Existing software and hardware capabilities of the ZGS computer were considered. The resulting data acquisition and control system is based on a mix of sequential logic and a minicomputer. Hardware considerations were based on a ten year life expectancy of the booster. Due to time, budget, and manpower constraints, the incorporation of the total design has been divided into three phases of implementation. The first phase is covered and the remaining phases are outlined

Space shuttle booster multi-engine base flow analysis

Science.gov (United States)

Tang, H. H.; Gardiner, C. R.; Anderson, W. A.; Navickas, J.

1972-01-01

A comprehensive review of currently available techniques pertinent to several prominent aspects of the base thermal problem of the space shuttle booster is given along with a brief review of experimental results. A tractable engineering analysis, capable of predicting the power-on base pressure, base heating, and other base thermal environmental conditions, such as base gas temperature, is presented and used for an analysis of various space shuttle booster configurations. The analysis consists of a rational combination of theoretical treatments of the prominent flow interaction phenomena in the base region. These theories consider jet mixing, plume flow, axisymmetric flow effects, base injection, recirculating flow dynamics, and various modes of heat transfer. Such effects as initial boundary layer expansion at the nozzle lip, reattachment, recompression, choked vent flow, and nonisoenergetic mixing processes are included in the analysis. A unified method was developed and programmed to numerically obtain compatible solutions for the various flow field components in both flight and ground test conditions. Preliminary prediction for a 12-engine space shuttle booster base thermal environment was obtained for a typical trajectory history. Theoretical predictions were also obtained for some clustered-engine experimental conditions. Results indicate good agreement between the data and theoretical predicitons.

Effect of reactor finiteness on the boundary condition at the surface of a booster section

International Nuclear Information System (INIS)

Wassef, W.A.

1982-01-01

Effect of reactor finiteness on the boundary condition at the surface of an absorbing booster embedded in the reactor core is studied and formulated. The model used in these calculations depends on the Pl-Transport coupling technique. This method takes into consideration the rigorous neutron transport behavior inside the booster medium, while the Pl-approximation in the bulk of the scattering medium surrounding the booster which can be considered infinite in most practical applications. The neutron flux gradient parallel to the surface of the booster is considered. The geometrical configuration of the reactor core cross section is circular or rectangular. Finiteness of the reactor is introduced in the general formulation through its dimensions or buckling. Extensive numerical results are given to demonstrate the dependence of the boundary condition at the surface of the booster section on the reactor finiteness and the different physical parameters

AGS BOOSTER BEAM POSITION, TUNE, AND LONGITUDINAL PROFILE DATA ACQUISITION SYSTEM

International Nuclear Information System (INIS)

BROWN, K.A.; AHRENS, L.; SEVERINO, F; SMITH, K.; WILINSKI, M

2003-01-01

In this paper we will describe a data acquisition system designed and developed for the AGS Booster. The system was motivated by the need to get high quality beam diagnostics from the AGS Booster. This was accomplished by locating the electronics and digital data acquisition close to the Booster ring, to minimize loss of bandwidth in the original signals. In addition we had to develop the system rapidly and at a low cost. The system consists of a Lecroy digital oscilloscope which is interfaced through a National Instruments LabView(trademark) server application, developed for this project. This allows multiple client applications to time share the scope without interfering with each other. We will present a description of the system design along with example clients that we have implemented

Reusable Boosters in a European-Russian Perspective

Science.gov (United States)

Deneu, François; Ramiandrasoa, Fabienne

2002-01-01

In 2001, EADS and Khrunichev SRPSC have initiated and carried out a working group devoted to the analysis of potential common studies and developments in the field of space activities. This working group came up with several propositions of interest, among which, the use of reusable boosters issued from Khrunichev previous design appeared to be promising when applied to heavy type launchers. Although the results required to be confirmed by detailed studies prior to final conclusions, preliminary studies have shown the interest of Ariane 5 configurations using such reusable booster in view of reducing the specific and launch cost as well as potentially increasing the performance. In November 2001, EADS and KHRUNICHEV SRPSC have started a study on an Ariane 5 plus reusable boosters configuration. This study aims at obtaining a better understanding of the advantages and drawbacks attached to such a use. Technical feasibility is more in depth analysed, with all recurring and not recurring aspects (including launch infrastructure modifications). Programmatic aspects are also addressed in order to better assess potential economic advantages and unavoidable drawbacks. Beyond that the identification of what could be, for western Europe and Russian players, an efficient and pay- off industrial organisation, is also a study theme of importance. This papers intends to present the main results achieved within this study and the propositions for the future which are likely to provide western Europe and Russia with stronger positions in the competitive field of launch business.

Automated tuning of the advanced photon source booster synchrotron

International Nuclear Information System (INIS)

Biedron, S.G.; Milton, S.V.

1997-01-01

The acceleration cycle of the Advanced Photon Source (APS) booster synchrotron is completed within 223 ms and is repeated at 2 Hz. Unless properly corrected, transverse and longitudinal injection errors can lead to inefficient booster performance. In order to simplify daily operation, automated tuning methods have been developed. Through the use of beam position monitor (BPM) reading, transfer line corrector magnets, magnet ramp timing, and empirically determined response functions, the injection process is optimized by correcting the first turn trajectory to the measured closed orbit. These tuning algorithms and their implementation are described here along with an evaluation of their performance

Multi-Physics Analysis of the Fermilab Booster RF Cavity

International Nuclear Information System (INIS)

Awida, M.; Reid, J.; Yakovlev, V.; Lebedev, V.; Khabiboulline, T.; Champion, M.

2012-01-01

After about 40 years of operation the RF accelerating cavities in Fermilab Booster need an upgrade to improve their reliability and to increase the repetition rate in order to support a future experimental program. An increase in the repetition rate from 7 to 15 Hz entails increasing the power dissipation in the RF cavities, their ferrite loaded tuners, and HOM dampers. The increased duty factor requires careful modelling for the RF heating effects in the cavity. A multi-physic analysis investigating both the RF and thermal properties of Booster cavity under various operating conditions is presented in this paper.

Booster Long 13 irradiation studies

Energy Technology Data Exchange (ETDEWEB)

Leveling, A.; Mokhov, N.; Moore, C.D.; /Fermilab

1998-06-01

Extraction from the Booster to the Main Ring occurred at Long Straight 13. The nature of the extraction process was such that 1% to 2% of the beam was lost in this region. There was an appreciable amount of beam extracted as shown in Table 1, which gives the yearly integrated intensities from 1973 to 1997. A simple model of the extraction losses was set up by Chandra Bhat utilizing the program CASIM. A sample output I shown in figure 1 which gives contours of stars/cm3 in the dirt, also schematically depicted are the three six feet deep sampling holes which were drilled to map out this cascade. One aspect of this study has been the study of the production of non-migrating nuclides and further study may in fact yield better values for the K parameter, the probability per star that an atom of the particular nuclide will be produced. Also the results of this study can give experimental numbers for the production of other nuclides when the amount of Na22 has been calculated. However, the most important part of this study has been the determination of the amount of tritium produced by extraction from the Booster and the experimentally determined migration rate. If we look at the top sample result in hole S2 of 777 pCi/ml of tritium and use the experimentally determined rate of migration and the depth to the aquifer of 13.1m, they calculate that the concentration will have decayed away to 1.1E-8 pCi/ml. If we look at the bottom sample, which is 11.3 m away from the aquifer, they calculate that the 116 pCi/ml will have decayed to 5.2E-8 pCi/ml. The conclusions is that the rate of migration determined over the 24 year irradiation history of the Booster extraction point is small enough that there is no problem with migration of tritium to the aquifer.

Tune measurement in the NSLS booster synchrotron

International Nuclear Information System (INIS)

Blum, E.B.; Nawrocky, R.

1993-01-01

The NSLS booster synchrotron can accelerate an electron beam from approximately 80 to 750 MeV in 0.7 sec. The betatron tunes can change during acceleration by as much as 0.1 units, causing beam loss as they cross resonance lines. Precise measurements with a conventional swept spectrum analyzer have always been difficult because of the rapid variation of tune as the magnets are ramped. We are now using a system based on a Tektronix 3052 digital spectrum analyzer that can obtain a complete frequency spectrum over a 10 MHz bandwidth in 200 μsec. Betatron oscillations are stimulated for the measurements by applying white noise to the beam through stripline electrodes. We will describe the instrumentation, our measurements of tune as a function time during the acceleration cycle, and the resulting improvements to the booster operation

Beam current monitoring in the AGS Booster and its transfer lines

International Nuclear Information System (INIS)

Witkover, R.L.; Zitvogel, E.; Castillo, V.

1991-01-01

The new AGS Booster is designed to accelerate low intensity polarized protons and heavy ions, and high intensity protons. The wide range of beam parameters and the vacuum, thermal and radiation environment, presented challenges in the instrumentation design. This paper describes the problems and solutions for the beam current monitors in the Booster and its transport lines. Where available, results of the initial operation will be presented. 11 refs., 3 figs

Study of solid rocket motors for a space shuttle booster. Volume 1: Executive summary

Science.gov (United States)

1972-01-01

The design, development, production, and launch support analysis for determining the solid propellant rocket engine to be used with the space shuttle are discussed. Specific program objectives considered were: (1) definition of engine designs to satisfy the performance and configuration requirements of the various vehicle/booster concepts, (2) definition of requirements to produce booster stages at rates of 60, 40, 20, and 10 launches per year in a man-rated system, and (3) estimation of costs for the defined SRM booster stages.

OPTIMASI DAYA MESIN DAN KONSUMSI BAHAN BAKAR MESIN TOYOTA SERI 5K MELALUI PENGGUNAAN PENGAPIAN BOOSTER

Directory of Open Access Journals (Sweden)

Mardani Ali Sera

2015-10-01

Full Text Available Proses pembakaran adalah proses secara fisik yang terjadi di dalam silinder. Proses pembakaran dimulai pada saat busi memercikkan bunga api hingga terjadi proses pembakaran. Dalam penelitian ini digunakan metode eksperimen yaitu membandingkan daya dan konsumsi bahan bakar antara pengapian standar dengan pengapian menggunakan booster. Berdasarkan data hasil uji coba perbandingan antara sistem pengapian standar dengan pengapian yang menggunakan booster dengan objek penelitian mesin Toyota seri 5K diketahui adanya kenaikan 2.61% daya menjadi 27.723 kW dari 27.17 kW antara sistem pengapian standar dengan pengapian yang menggunakan booster pada putaran mesin 2400 rpm. Sedangkan prosentase kenaikan rerata daya sebesar 2.79 %. Penggunaan booster juga membuat penggunaan konsumsi bahan bakar spesifik (sfc antara sistem pengapian standar dengan pengapian yang menggunakan booster. Prosentase penurunan rerata konsumsi bahan bakar spesifik (sfc sebesar 6.99%. Pada sistem pengapian yang menggunakan booster, sfc minimum sebesar 0.219 kg/kWh pada putaran mesin 2200 rpm. Pada pengapian standar sfc minimum sebesar 0.231 kg/kWh pada putaran mesin 2400 rpm.

Response to booster doses of hepatitis B vaccine among young adults who had received neonatal vaccination.

Directory of Open Access Journals (Sweden)

Paul K S Chan

Full Text Available Newborns who have received hepatitis B immunization in 1980s are now young adults joining healthcare disciplines. The need for booster, pre- and post-booster checks becomes a practical question.The aim of this study is to refine the HBV vaccination policy for newly admitted students in the future.A prospective study on medical and nursing school entrants to evaluate hepatitis B serostatus and the response to booster doses among young adults.Among 212 students, 17-23-year-old, born after adoption of neonatal immunization, 2 (0.9% were HBsAg positive, 40 (18.9% were anti-HBs positive. At 1 month after a single-dose booster for anti-HBs-negative students, 14.5% had anti-HBs 100 mIU/mL, respectively. The anti-HBs levels were significantly higher for females than males (mean [SD]: 431 [418] vs. 246 [339] mIU/mL, P = 0.047. At 2-4 month after the third booster dose, 97.1% had anti-HBs >100 mIU/mL and 2.9% had 10-100 mIU/mL.Pre-booster check is still worthwhile to identify carriers among newly recruited healthcare workers born after adoption of neonatal immunization. A 3-dose booster, rather than a single dose, is required for the majority to achieve an anti-HBs level >100 mIU/mL, as memory immunity has declined in a substantial proportion of individuals. Cost-effectiveness of post-booster check for anti-HBs is low and should be further evaluated based on contextual specific utilization of results.

Integral Ramjet Booster Demonstration Program

Science.gov (United States)

1975-02-01

vibration loads before motor firing at -65, +70, and +1650F, (2) The chambers are fabricated from roll and welded ( TIG ) L-605 sheet that is cold...Typical Integral Booster Internal Configuration Keyhole Grain Pressure and Thrust Versus Time (+700F, Sea Level) Keyhole Grain Pressure and...Thrust Versus Time (+1650F, Sea Level) Keyhole Grain Pressure and Thrust Versus Time (-65^, Sea Level) Radial-Slot Grain Design Radial-Slot Grain

Injection system of teh SSC Medium Energy Booster

International Nuclear Information System (INIS)

Mao, N.; Gerig, R.; McGill, J.; Brown, K.

1994-04-01

The Medium Energy Booster (MEB) is the third of the SSCL accelerators and the largest of the resistive magnet synchrotrons. It accelerates protons from an injection momentum of 12 GeV/c to a top momentum of 200 GeV/c. A beam injection system has been designed to inject the beam transferred from the Low Energy Booster onto the MEB closed orbit in the MEB injection insertion region. The beam is injected via a vertical bending Lambertson septum magnet and a horizontal kicker with appropriate matching and very little beam loss and emittance dilution. The beam optics of the injection system is described in this paper. The required parameters of the Lambertson septum magnet and the injection kicker are given

[Safety and immunogenicity of a 7-valent pneumococcal conjugate vaccine (Prevenar) booster dose in healthy Chinese toddlers].

Science.gov (United States)

Li, Rong-cheng; Li, Feng-xiang; Li, Yan-ping

2009-06-01

To evaluate the safety and immunogenicity of the booster dose of 7 valent pneumococcal conjugate vaccine (PCV7) to the healthy Chinese toddlers who had received 3 primary doses. Four hundred and eighty-eight Chinese toddlers received a booster dose of PCV7 at age of 12-15 months following a primary series of the vaccine given at ages 3, 4, 5 months separately with Diphtheria Tetanus Acellular Pertussis Combined Vaccine (DTaP) in Group 1 or concurrently with DTaP in Group 2. Following the booster dose immunization, each subject was followed up for 30 days to observe the safety of the vaccine. Blood samples were taken from a subset of subjects prior and post 30 days the booster dose immunization to evaluate immunogenicity. A high proportion of subjects in Group 1 (89%) and Group 2 (91%) remained afebrile after the booster dose. Local reactions to the PCV7 booster dose were generally mild. For each serotype, the rise in GMC (post-/pre-vaccination) showed a statistically significant difference (P<0.0001) between both groups. PCV7 administered as a booster dose is generally safe, well tolerate, and immunogenic in healthy Chinese toddlers.

Analysis of resonance-driving imperfections in the AGS Booster

International Nuclear Information System (INIS)

Gardner, C.; Shoji, Y.; Danby, G.; Glenn, J.W.; Jackson, G.J.; Soukas, A.; van Asselt, W.; Whalen, C.

1994-01-01

At the design intensity of 1.5 x 10 13 ppp, the space charge tune shift in the AGS Booster at injection has been estimated to be about 0.35. The beam tunes are therefore spread over many lower order resonance lines and the associated stopbands must be corrected in order to minimize the amplitude growth due to resonance excitation. This requires proper compensation of the resonance-driving harmonics which result from random magnetic field errors. The observation and correction of second and third order resonance stopbands in the AGS Booster is reviewed, and an analysis of magnetic field imperfections based on the required corrections is given

Design of the AGS Booster Beam Position Monitor electronics

International Nuclear Information System (INIS)

Ciardullo, D.J.; Smith, G.A.; Beadle, E.R.

1991-01-01

The operational requirements of the AGS Booster Beam Position Monitor system necessitate the use of electronics with wide dynamic range and broad instantaneous bandwidth. Bunch synchronization is provided by a remote timing sequencer coupled to the local ring electronics via digital fiber-optic links. The Sequencer and local ring circuitry work together to provide single turn trajectory or average orbit and intensity information, integrated over 1 to 225 bunches. Test capabilities are built in for the purpose of enhancing BPM system accuracy. This paper describes the design of the Booster Beam Position Monitor electronics, and presents performance details of the front end processing, acquisition and timing circuitry

Measured longitudinal beam impedance of booster gradient magnets; TOPICAL

International Nuclear Information System (INIS)

James L Crisp and Brian J. Fellenz

2001-01-01

The Booster gradient magnets have no vacuum pipe which forces the beam image current to flow along the laminated pole tips. Both D and F style magnets were measured with a stretched wire to determine the longitudinal beam impedance caused by these laminations. Results are compared to calculations done 30 years ago. The inductive part of the magnet impedance is interesting because it partially compensates for the negative inductance effects of space charge on the beam. An R/L circuit consisting of 37K(center d ot) in parallel with between 40 and 100uH is a reasonable approximation to the total impedance of Booster magnet laminations

Observation and correction of resonance stopbands in the AGS Booster

International Nuclear Information System (INIS)

Gardner, C.; Shoji, Y.; Ahrens, L.; Glenn, J.W.; Lee, Y.Y.; Roser, T.; Soukas, A.; van Asselt, W.; Weng, W.T.

1993-01-01

At the design intensity of 1.5 x 10 13 ppp, the space charge tune shift in the AGS Booster at injection has been estimated to be about 0.35. Therefore, the beam is spread over may lower order resonance lines and the stopbands have to be corrected to minimize the amplitude growth by proper compensation of the driving harmonics resulting from random errors. The observation and correction of second and third order resonance stopbands in the AGS Booster, and the establishment of a favorable operating point at high intensity are discussed

Vertical septum magnets for distributing the beam to the 4 PS Booster rings

CERN Multimedia

Ordan, Julien Marius

2017-01-01

To facilitate H- injection from Linac4 to the PS Booster via the transfer line the BI.SMV10 (Booster Injection Septum Magnet Vertical) provides the vertical deflection of the 160 MeV H- beam to rings 1, 2 and 4 of the Booster. Currently this system is capable of deflecting 50 MeV protons and comprises an assembly of ferrite type magnets in an “omega” section vacuum tank (see fig. 1). The current system shall be replaced with a UHV compatible vacuum chamber incorporating 3 sets of double septum magnets, pulsed from 3 individual power supplies via transformers with 12:1 ratio.

Cabling design of booster and storage ring construction progress of TPS

International Nuclear Information System (INIS)

Wong, Y.-S.; Liu, K.-B.; Liu, C.-Y.; Wang, B.-S.

2017-01-01

The 2012 Taiwan Photon Source (TPS) cable construction project started after 10 months to complete the cable laying and installation of power supply. The circumference of the booster ring (BR) is 496.8 m, whereas that of the storage ring (SR) is 518.4 m. Beam current is set to 500 mA at 3.3 GeV. The paper on grounding systems discusses the design of the ground wire (< 0.2 Ω) with low impedance, power supply of the accelerator and cabling tray. The flow and size of the ground current are carefully evaluated to avoid grounded current from flowing everywhere, which causes interference problems. In the design of the TPS, special shielding will be established to isolate the effects of electromagnetic interference on the magnet and ground current. Booster ring dipoles are connected by a series of 54-magnet bending dipole; the cable size of its stranded wire measures 250 mm"2, with a total length of 5000 m. Booster ring and storage ring quadrupoles have 150 magnets; the cable size of their stranded wire is 250 mm"2, with a total length of 17000 m. Storage ring dipole consists of 48 magnets; the cable size of its stranded wire is 325 mm"2, with a total length of 6000 m. This study discusses the power supply cabling design of the storage ring and booster ring construction progress of TPS. The sections of this paper are divided into discussions of the construction of the control and instrument area, cabling layout of booster ring and storage ring, as well as the installation and commission machine. This study also discusses the use of a high-impedance meter to determine the effect of cabling insulation and TPS power supply machine on energy transfer to ensure the use of safe and correct magnet.

Compensation of dogleg effect in Fermilab Booster

CERN Document Server

Xiao Biao Huang

2003-01-01

The edge focusing of dogleg magnets in Fermilab Booster has been causing severe distortion to the horizontal linear optics. The doglegs are vertical rectangular bends, therefore the vertical edge focusing is canceled by body focusing and the overall effect is focusing in the horizontal plane. The maximum horizontal beta function is changed from 7m to 46.9m and maximum dispersion from 3.19m to 6.14m. Beam size increases accordingly. This is believed to be one of the major reasons of beam loss. In this technote we demonstrate that this effect can be effectively corrected with Booster's quadrupole correctors in short straight sections (QS). There are 24 QS correctors which can alter horizontal linear optics with negligible perturbation to the vertical plane. The currents of correctors are determined by harmonic compensation, i.e., cancellation of dogleg's harmonics that are responsible for the distortion with that of QS correctors. By considering a few leading harmonics, the ideal lattice can be partly restored....

Blood Pressure Directed Booster Trainings Improve Intensive Care Unit Provider Retention of Excellent Cardiopulmonary Resuscitation Skills.

Science.gov (United States)

Wolfe, Heather; Maltese, Matthew R; Niles, Dana E; Fischman, Elizabeth; Legkobitova, Veronika; Leffelman, Jessica; Berg, Robert A; Nadkarni, Vinay M; Sutton, Robert M

2015-11-01

Brief, intermittent cardiopulmonary resuscitation (CPR) training sessions, "Booster Trainings," improve CPR skill acquisition and short-term retention. The objective of this study was to incorporate arterial blood pressure (ABP) tracings into Booster Trainings to improve CPR skill retention. We hypothesized that ABP-directed CPR "Booster Trainings" would improve intensive care unit (ICU) provider 3-month retention of excellent CPR skills without need for interval retraining. A CPR manikin creating a realistic relationship between chest compression depth and ABP was used for training/testing. Thirty-six ICU providers were randomized to brief, bedside ABP-directed CPR manikin skill retrainings: (1) Booster Plus (ABP visible during training and testing) versus (2) Booster Alone (ABP visible only during training, not testing) versus (3) control (testing, no intervention). Subjects completed skill tests pretraining (baseline), immediately after training (acquisition), and then retention was assessed at 12 hours, 3 and 6 months. The primary outcome was retention of excellent CPR skills at 3 months. Excellent CPR was defined as systolic blood pressure of 100 mm Hg or higher and compression rate 100 to 120 per minute. Overall, 14 of 24 (58%) participants acquired excellent CPR skills after their initial training (Booster Plus 75% vs 50% Booster Alone, P = 0.21). Adjusted for age, ABP-trained providers were 5.2× more likely to perform excellent CPR after the initial training (95% confidence interval [95% CI], 1.3-21.2; P = 0.02), and to retain these skills at 12 hours (adjusted odds ratio, 4.4; 95% CI, 1.3-14.9; P = 0.018) and 3 months (adjusted odds ratio, 4.1; 95% CI, 1.2-13.9; P = 0.023) when compared to baseline performance. The ABP-directed CPR booster trainings improved ICU provider 3-month retention of excellent CPR skills without the need for interval retraining.

Design and status of the AGS booster accelerator

International Nuclear Information System (INIS)

Forsyth, E.B.; Lee, Y.Y.

1987-01-01

Comments are given on some areas of the design considered for the AGS Booster Accelerator, including lattice design, energy and repetition rate, injection, radio frequency system, and the vacuum system. The current status is then briefly described

The particle suppliers

CERN Multimedia

CERN Bulletin

2010-01-01

Particles are supplied to the LHC by six accelerators inter-connected by several kilometres of transfer lines. This represents yet another complex chain of processes whereby particles are produced, bunched, synchronised and injected into the LHC at the precise moment it's ready to receive them. In other words, for collisions to be produced at the end of the chain, all the injectors must be in perfect working order.   Among all the questions asked by the many visitors to CERN, one in particular comes up time and time again: "Why don't you just connect the LHC directly to the proton source?" In other words, why do you need this whole chain of accelerators acting as an "injector" for the LHC? Before colliding inside the LHC, particles first have to pass through no fewer than six different accelerators: the 90 keV duoplasmatron source, the 750 keV RFQ, the 50 MeV Linac 2, the 1.4 GeV synchrotron injector ("PS Booster" or PSB), the 25 GeV Proton Sy...

Design and status of the AGS booster accelerator

Energy Technology Data Exchange (ETDEWEB)

Forsyth, E.B.; Lee, Y.Y.

1987-01-01

Comments are given on some areas of the design considered for the AGS Booster Accelerator, including lattice design, energy and repetition rate, injection, radio frequency system, and the vacuum system. The current status is then briefly described. (LEW)

Energy-efficient operation of a booster RF system for Taiwan light source operated in top-up mode

International Nuclear Information System (INIS)

Yeh, Meng-Shu; Wang, Chaoen; Chang, Lung-Hai; Chung, Fu-Tsai; Yu, Tsung-Chi; Lin, Ming-Chyuan; Chen, Ling-Jhen; Yang, Tz-Te; Chang, Mei-Hsia; Lin, Yu-Han; Tsai, Ming-Hsun; Lo, Chih-Hung; Liu, Zong-Kai

2015-01-01

Contemporary light sources operate in a top-up mode to maintain their photon intensity quasi-constant so as to improve significantly the thermal stability of the photon beam and to maximize ultimately the average photon flux at a designed maximum operational beam current. Operating in a top-up mode requires frequent beam injection from the synchrotron booster to the storage ring of the light source, but the injection intervals occupy only a tiny portion of the operational time of the integrated machine. To maintain a high operational reliability, the booster RF system practically operates necessarily under injection conditions around the clock and consumes full electric power whether during top-up injection or not. How to decrease the power consumption of the booster RF system during its stand-by time but not to sacrifice the reliability and availability of the RF system is obviously of fundamental interest for routine operation of the light source in a top-up mode. Here, an energy-efficient operation of a booster RF system adaptive to top-up operation of a light source is proposed that has been developed, realized and integrated into the booster RF system of the Taiwan Light Source (TLS), and routinely operated since the end of year 2008. The klystron cathode current and RF gap voltage of the booster's accelerating RF cavity are both periodically modulated to adapt the injection rhythm during top-up operation, which results in decreased consumption of electric power of the booster RF system by more than 78%. The impact on the reliability and availability of the booster RF system has been carefully monitored during the past five operational years, delivering more than 5000 h scheduled user beam time per year. The booster RF system retains its excellent reliability and availability as previously. Neither a decrease of the service time nor an induced reliability issue from the klystron or any high-power high-voltage component of the transmitter has been

Preliminary study of AC power feeders for AGS booster

International Nuclear Information System (INIS)

Meth, M.

1992-01-01

It has been proposed that the AGS Heavy Ion/Proton Booster be excited directly from the electric power distribution system without intervening an energy storage buffer such as an MG set or a magnetic energy buffer. The average power requirement of the AGS Booster is less than many single-loads presently housed on the lab site. However, the power swing will be the largest single pulsating load on the lab site. The large power swings will impact on the power grid producing utility-line disturbances such as voltage fluctuations and harmonic generation. Thus, it is necessary to carefully evaluate the quality of the electric power system resulting from the interconnection, such that the utility system is not degraded either on the lab site or at LILCO's substation

The 1.4 GeV PS Booster in its tunnel.

CERN Multimedia

Patrice Loïez

2002-01-01

The PS Improvement Programme, launched as early as 1964, had a "Booster" as the key element in the quest for higher beam intensity and density. These were limited in the PS at injection of the 50 MeV proton beam from the linac by the incoherent (Laslett-) Q-shift. Boosting the linac beam to 800 MeV would raise the PS intensity limit by an order of magnitude, from 1E12 protons per pulse to 1E13. The main motivation was the supply of intense beams to the ISR. Soon, the Booster proved to be crucial for the neutral current experiment. A unique feature of the Booster are its 4 superposed rings. Its lattice is also unusual: between its 32 bending magnets, every second straight section contains a quadrupole triplet (F,D,F), while the alternate ones are drift spaces (mostly filled with essential components like septa, kickers, RF-cavities, etc.). In each picture we see one of the 16 periods. Following the direction of the beam from right to left: a bending magnet (green); an empty straight section; a bending magnet; ...

Magnet power supply system for the ALS storage ring and booster

International Nuclear Information System (INIS)

Jackson, L.T.; Luchini, K.; Lutz, I.

1993-05-01

The Magnet Power Supply System is described by specification, design, hardware, and operating experience. A unique system for the one Hz, 1.5 GeV Booster, where the wideband QF and QD power supplies track the dipole current to within 0.1% at injection will be detailed. AC distribution system considerations related to inverting the stored energy of the booster magnet back into power grid will be discussed. The rational for linear correctors and individual quad supplies (225 total units) will be placed within the context of the storage-ring requirements

High performance stream computing for particle beam transport simulations

International Nuclear Information System (INIS)

Appleby, R; Bailey, D; Higham, J; Salt, M

2008-01-01

Understanding modern particle accelerators requires simulating charged particle transport through the machine elements. These simulations can be very time consuming due to the large number of particles and the need to consider many turns of a circular machine. Stream computing offers an attractive way to dramatically improve the performance of such simulations by calculating the simultaneous transport of many particles using dedicated hardware. Modern Graphics Processing Units (GPUs) are powerful and affordable stream computing devices. The results of simulations of particle transport through the booster-to-storage-ring transfer line of the DIAMOND synchrotron light source using an NVidia GeForce 7900 GPU are compared to the standard transport code MAD. It is found that particle transport calculations are suitable for stream processing and large performance increases are possible. The accuracy and potential speed gains are compared and the prospects for future work in the area are discussed

Liquid Rocket Booster (LRB) for the Space Transportation System (STS) Systems Study; Volume 1 - Executive Summary

National Research Council Canada - National Science Library

Ware, Larry

1989-01-01

...) solid rocket boosters (SRBs) with liquid rocket boosters (LRBs), Figure 1.0-1. The main objectives of a LRB substitution for the SRB were increased STS safety and reliability and increased payload performance...

Misuse of booster cushions - an observation study of children's performance during buckling up.

Science.gov (United States)

Osvalder, Anna-Lisa; Bohman, Katarina

2008-10-01

Booster cushions are effective tools to protect children from injuries in car crashes, but there remains a large amount of misuse. The aim of this study was to assess potential misuse of booster cushions in an observational laboratory study, and to identify whether booster cushion design, age or clothing had any effect. 130 Swedish children from the ages of 4-12 years participated. Each child buckled up on an integrated and on an aftermarket booster cushion in the rear seat. The older children also buckled up with seat belt only. Interviews, observations and body measurements were performed. Time to buckle up and amount of belt slack were registered. Photographs were taken to document misuse. Results showed that 77% failed to perform correct belt routing on the aftermarket cushion, independent of age, although they were familiar with this system. The misuse rate for the integrated cushion was only 4%. No misuse was found for seat belt only. Few children tightened the belt. The belt slack increased when wearing winter jackets. This indicates the importance of adding pretensioners to the rear seat. Sled tests with HIII&TNO 6y dummies were also performed for the most frequent misuse situations found. The main conclusion is that an integrated booster cushion has many advantages compared to an aftermarket cushion regarding both safety and comfort. It is easy and quick to handle, has few possibilities for misuse, has an intuitive design, the buckling up sequence is equal to buckling up with an ordinary seat belt, and younger children can buckle up correctly.

Integrated hydraulic booster/tool string technology for unfreezing of stuck downhole strings in horizontal wells

Science.gov (United States)

Tian, Q. Z.

2017-12-01

It is common to use a jarring tool to unfreeze stuck downhole string. However, in a horizontal well, influenced by the friction caused by the deviated section, jarring effect is poor; on the other hand, the forcing point can be located in the horizontal section by a hydraulic booster and the friction can be reduced, but it is time-consuming and easy to break downhole string using a large-tonnage and constant pull force. A hydraulic booster - jar tool string has been developed for unfreezing operation in horizontal wells. The technical solution involves three elements: a two-stage parallel spring cylinder structure for increasing the energy storage capacity of spring accelerators; multiple groups of spring accelerators connected in series to increase the working stroke; a hydraulic booster intensifying jarring force. The integrated unfreezing tool string based on these three elements can effectively overcome the friction caused by a deviated borehole, and thus unfreeze a stuck string with the interaction of the hydraulic booster and the mechanical jar which form an alternatively dynamic load. Experimental results show that the jarring performance parameters of the hydraulic booster-jar unfreezing tool string for the horizontal wells are in accordance with original design requirements. Then field technical parameters were developed based on numerical simulation and experimental data. Field application shows that the hydraulic booster-jar unfreezing tool string is effective to free stuck downhole tools in a horizontal well, and it reduces hook load by 80% and lessens the requirement of workover equipment. This provides a new technology to unfreeze stuck downhole string in a horizontal well.

Preliminary Design Study of a Pre-booster Damping Ring for the FCC e+e− Injector

CERN Document Server

Etisken, O; Papaphilippou, Y

2017-01-01

The aim of the FCC e+e− lepton collider is to collide particles in the energy range 40–175 GeV. The FCC e+e− injector complex needs to produce and transport high-intensity e+e− beams at a fast repetition rate of about 0.1 Hz to top up the collider at its collision energy. A basic parameter set exists for all collider energies, assuming a 10 GeV linac operating with a large number of bunches accumulating in the existing SPS, which serves as pre-accelerator and damping ring before the bunches are transferred to the high-energy booster. The purpose of this study is to provide the conceptual design of an alternative damping and accelerator ring, replacing the SPS in the current scheme. This ring will have an injection energy of around 6 GeV and an extraction energy of around 20 GeV. Apart from establishing the basic ring parameters, the final study will include the optics design and layout, and single particle linear and non-linear dynamics optimization, including magnetic and alignment error tolerances. ...

Present state of tandem superconductive booster of JAERI

Energy Technology Data Exchange (ETDEWEB)

Takeuchi, Suehiro; Matsuda, Makoto; Kanazawa, Shuhei; Yoshida, Tadashi; Ouchi, Isao; Shoji, Tokio [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

1996-12-01

The superconductive booster constructed rear-stage accelerator of the tandem accelerator of the Tokai Research Establishment, JAERI (Japan Atomic Energy Research Institute), was completed in construction of its whole system on October, 1993, and through its beam accelerating test and remodulation its design characteristics were established on September, 1994. From November, 1994 to April, 1995 a repulsion-forming nuclear isolation apparatus was installed to modulate at target room, and was begun to use on June, 1995. The beam reaccelerated at the booster was used mainly for nuclear spectroscopy experiment, a collaborative research was developed using mini-crystal balls made by collecting from University of Tsukuba and so forth. The accelerating part of the booster is a phase independent setting type Linac consisting of 40 niobium superconducting holes with 1/4 wave-length type and 130 MHz in frequency, in which a hole can form 5 MV/m of accelerating electric field for 4 W of radio frequency spent power of 0.75 MV of accelerating voltage per hole, to form 30 MV of voltage in a whole. 4 holes are contained into each 10 cryostats, respectively. In accelerating tests, Si, Cl, Ni, Ge, Ag, I and Au ions are accelerated to establish 30 mV of total accelerating voltage in its design value, which reaches to their expected energy characteristics. Its used days in this year are 25 days after beginning of its use, and operating days of the cooling apparatus was 135 days in total. (G.K.)

Concentrated Ground Plane Booster Antenna Technology for Multiband Operation in Handset Devices

Directory of Open Access Journals (Sweden)

C. Picher

2014-12-01

Full Text Available The current demand in the handset antenna field requires multiband antennas due to the existence of multiple communication standards and the emergence of new ones. At the same time, antennas with reduced dimensions are strongly required in order to be easily integrated. In this sense, the paper proposes a compact radiating system that uses two non-resonant elements to properly excite the ground plane to solve the abovementioned shortcomings by minimizing the required Printed Circuit Board (PCB area while ensuring a multiband performance. These non-resonant elements are called here ground plane boosters since they excite an efficient mode of the ground plane. The proposed radiating system comprises two ground plane boosters of small dimensions of 5 mm x 5 mm x 5 mm. One is in charge of the low frequency region (0.824-0.960 GHz and the other is in charge of the high frequency region (1.710-2.170 GHz. With the aim of achieving a compact configuration, the two boosters are placed close to each other in a corner of the ground plane of a handset device (concentrated architecture. Several experiments related to the coupling between boosters have been carried out in two different platforms (barphone and smartphone, and the best position and the required matching network are presented. The novel proposal achieves multiband performance at GSM850/900/1800/1900 and UMTS.

History of the ZGS 500 MeV booster.

Energy Technology Data Exchange (ETDEWEB)

Simpson, J.; Martin; R.; Kustom, R.

2006-05-09

The history of the design and construction of the Argonne 500 MeV booster proton synchrotron from 1969 to 1982 is described. This accelerator has since been in steady use for the past 25 years to power the Argonne Intense Pulsed Neutron Source (IPNS).

Improving the performance of booster heat pumps using zeotropic mixtures

DEFF Research Database (Denmark)

Zühlsdorf, B.; Meesenburg, W.; Ommen, T. S.

2018-01-01

Abstract This study demonstrated an increase in the thermodynamic performance of a booster heat pump, which was achieved by choosing the working fluid among pure and mixed fluids. The booster heat pump was integrated in an ultra-low-temperature district heating network with a forward temperature...... of 40 °C to produce domestic hot water, by heating part of the forward stream to 60 °C, while cooling the remaining part to the return temperature of 25 °C. The screening of working fluids considered 18 pure working fluids and all possible binary mixtures of these fluids. The most promising solutions...... heat supply system while being economically competitive to pure fluids....

A FET based kicker for a charge booster for the TRIUMF ISAC project

International Nuclear Information System (INIS)

Barnes, M.J.; Wait, G.D.

2001-07-01

A charge booster unit is required as part of an upgrade to the ISAC facility at TRIUMF. ISAC is an isotope separator coupled to an accelerator. ISAC is presently capable of accelerating only isotopes with atomic mass up to 30. The charge booster will allow ISAC to accelerate all the masses in the periodic table. A fast kicker system has been built to study the characteristics of an existing charge booster, designed by ISN in Grenoble, to assess the suitability of using this charge booster at TRIUMF. This fast kicker will subsequently be used in the TRIUMF ISAC facility for time of flight separation of the chosen charge and to recycle the higher and lower charges back to the charge booster. This will increase the efficiency from 10% to 60%. The kicker system includes a pair of deflector plates. One plate is charged up to -3.5 kV by a PET based modulator, while the other plate is held at ground potential. The modulator consists of two stacks of FETs operating in push pull with variable output voltage, pulse width, and repetition rate from virtually DC to 52 kHz. The measured high voltage output pulse rise and fall times are 63 ns and the minimum pulse width is 350 ns. The maximum pulse width is dependent upon the repetition rate. The large dynamic range for the repetition rate and pulse width required a novel circuit design and control technique, which also resulted in an energy efficient kicker system. This paper describes the design of the kicker system and shows the results of measurements. (author)

Frequency control of RF booster cavity in TRIUMF

International Nuclear Information System (INIS)

Fong, K.; Laverty, M.

1993-01-01

A booster is used in the TRIUMF cyclotron to increase the energy gain per turn for beam orbits corresponding to energies greater than 370 MeV. It operates at 92.24 MHz, the 4 th harmonic of the cyclotron main rf, and at a nominal voltage of 150 kV. Excitation is provided by a 90 kW rf system that is phase locked to the main rf. When the main rf is interrupted due to sparking or other causes, a controller built into the low frequency source of the booster rf system disables the phase-locked loop, and reconfigures the source as a temperature stabilized oscillator operating at the last locked frequency. When the cyclotron rf is restored it usually will be at different frequency. The oscillator tunes automatically to this new frequency. The acquisition time is extended by the controller to match the response time of the mechanical tuner in the cavity

75 FR 63766 - Digital Low Power Television, Television Translator, and Television Booster Stations and Digital...

Science.gov (United States)

2010-10-18

...] Digital Low Power Television, Television Translator, and Television Booster Stations and Digital Class A... TV, TV Translator or TV Booster Station, FCC Form 346; 47 CFR 74.793(d); LPTV Out-of-Core Digital... collection requirements: 47 CFR 74.793(d) proposes that certain digital low power and TV translator stations...

SNS RING STUDY AT THE AGS BOOSTER.

Energy Technology Data Exchange (ETDEWEB)

ZHANG, S.Y.; AHRENS, L.; BEEBE-WANG, J.; BLASKIEWICZ, M.; FEDOTOV, A.; GARDNER, C.; LEE, Y.Y.; LUCCIO, A.; MALITSKY, N.; ROSER, T.; WENG, W.T.; WEI, J.; ZENO, K.; REECE, K.; WANG, J.G.

2000-06-30

During the g-2 run at the BNL AGS in early 2000, a 200 MeV storage-ring-like magnetic cycle has been set-up and tuned at the Booster in preparing for the Spallation Neutron Source (SNS) accumulator ring study. In this article, we report the progress of the machine set-up, tuning, some preliminary studies, and the future plan.

Relativistic heavy ions from the BNL [Brookhaven National Laboratory] booster medical research and technological applications

International Nuclear Information System (INIS)

Thieberger, P.

1990-05-01

The BNL Booster, now nearing completion, was designed to inject protons and heavy ions into the Alternating Gradient Synchrotron (AGS) for further acceleration. In the future, ion beams from the AGS will in turn be further accelerated in the Relativistic Heavy Ion Collider (RHIC). Given the wide range of ion masses, energies and beam intensities the Booster will generate, other important applications should be considered. Dedicated use of the Booster for such applications may be possible during limited periods. However shared use would be preferable from the points of view of availability, affordability and efficiency. While heavy ions of a given isotope are injected into the AGS, the same or other ion species from the Booster could be simultaneously delivered to a new irradiation area for treatment of patients, testing of electronic devices or other applications and research. To generate two different beam species, ion sources on both Tandem accelerators would be used; one for AGS injection and the other one for a time-sharing application. Since the beam transport from the Tandems to the Booster can not be rapidly adjusted, it will be necessary to select beams of identical magnetic rigidity. The present study was performed to determine to what extent this compatibility requirement imposes limitations on the available ion species, energies and/or intensities

Superconducting linac booster

International Nuclear Information System (INIS)

Srinivasan, B.; Betigeri, M.G.; Pandey, M.K.; Pillay, R.G.; Kurup, M.B.

1997-01-01

The report on superconducting LINAC booster, which is a joint project of Bhabha Atomic Research Centre (BARC) and Tata Institute of Fundamental Research (TIFR), brings out the work accomplished so far towards the development of the technology of superconducting LINAC to boost the energy of ions from the 14UD Pelletron. The LINAC is modular in construction with each module comprising of a helium cryostat housing four lead-plated quarter wave resonators. The resonators are superconducting for temperatures below 7.19K. An energy boost of 2 MeV/q per module is expected to be achieved. The first module and the post-tandem superbuncher have been fabricated and tested on the LINAC beam line. This report gives a summary of the technological achievements and also brings out the difficulties encountered during the R and D phase. (author)

76 FR 44821 - Digital Low Power Television, Television Translator, and Television Booster Stations and To Amend...

Science.gov (United States)

2011-07-27

...] Digital Low Power Television, Television Translator, and Television Booster Stations and To Amend Rules... Digital Low Power Television, Television Translator, and Television Booster Stations and to Amend Rules... translator facilities in the 700 MHz band. These provisions provide procedures for a primary wireless...

76 FR 72849 - Digital Low Power Television, Television Translator, and Television Booster Stations and To Amend...

Science.gov (United States)

2011-11-28

...] Digital Low Power Television, Television Translator, and Television Booster Stations and To Amend Rules... for Digital Low Power Television, Television Translator, and Television Booster Stations and to Amend... television, TV translator, and Class A television station DTV licensees''). The Commission has also revised...

PS Booster Orbit Correction

CERN Document Server

Chanel, M; Rumolo, G; Tomás, R; CERN. Geneva. AB Department

2008-01-01

At the end of the 2007 run, orbit measurements were carried out in the 4 rings of the PS Booster (PSB) for different working points and beam energies. The aim of these measurements was to provide the necessary input data for a PSB realignment campaign during the 2007/2008 shutdown. Currently, only very few corrector magnets can be operated reliably in the PSB; therefore the orbit correction has to be achieved by displacing (horizontally and vertically) and/or tilting some of the defocusing quadrupoles (QDs). In this report we first describe the orbit measurements, followed by a detailed explanation of the orbit correction strategy. Results and conclusions are presented in the last section.

Charge exchange studies with Gold ions at the Brookhaven Booster and AGS

International Nuclear Information System (INIS)

Ahrens, L.A.; Hseuh, H.C.; Roser, T.

1994-01-01

Efficient acceleration of Gold ions to ll GeV/nucleon places strong constraints on the vacuum and also on the choice of thickness and material of the necessary stripping foils. Results of a number of detailed experimental studies performed with the Gold beam at the Brookhaven Booster and AGS to determine the relevant electron stripping and pick-up probabilities are presented. Of particular interest is the lifetime of the relatively low energy, partially stripped Gold beam in the Booster and the stripping efficiency to Helium-like AU +77 for injection into the AGS

Superconducting LINAC booster for the pelletron accelerator at Bombay

International Nuclear Information System (INIS)

Pillay, R.G.; Kurup, M.B.; Jain, A.K.; Biswas, D.; Kori, S.A.; Srinivasan, B.

1989-01-01

A superconducting heavy ion linear accelerator being constructed as a booster for the 14 UD pelletron installed recently at Bombay. The work involved in this project and the progress made so far are reviewed. (author). 15 refs., 8 figs

Pressure measurements in the AGS Booster ultra-high vacuum system

International Nuclear Information System (INIS)

Gabusi, J.; Geller, J.; Hseuh, H.C.; Mapes, M.; Stattel, P.

1992-01-01

An average pressure of mid 10 -11 Torr has been achieved and maintained in the AGS Booster ring vacuum system during its first year of operation. This ultra-high vacuum system is monitored through remote controlled Bayard-Alpert Gauges (BAGs). The characteristics of the pressure measurements with BAGs over the long cable lengths (up to 200 m) and under various accelerator operating conditions will be described. Two types of noise in the pressure readouts have been identified; the electromagnetic interference (EMI) associated with the acceleration cycles of the Booster and the environment noise associated with the temperature of the collector cables. The magnitude of the noise pickup depends on the routing of the collector cables and reaches the equivalent pressure of low 10 -9 Torr

Response of booster dose of cuban recombinant hepatitis-B vaccine in nonresponder and hyporesponder children

International Nuclear Information System (INIS)

Dahifar, H.; Mousavi, F.; Ghorbani, A.

2007-01-01

Acute hepatitis B infection can debilitate a patient for weeks and occasionally has a fatal outcome, while chronic infection is a major threat to the individual. To assess response of nonresponder and hyporesponder children to booster dose of Cuban recombinant hepatitis B vaccine. An interventional, descriptive study has been conducted on children who had been immunized with Cuban recombinant Hepatitis B vaccine and their antibody titers were <10mIU/ml (nonresponder) and 10-100mIU/ml (hyporesponder) administered booster dose of the same vaccine in their Deltoid muscles. The response of 141 children with the mean age of 1.9 years to booster dose of vaccine were 94.3% and 100% vaccines with the first and second booster dose of vaccination respectively. The anti-HBs titer in nonresponders and hyporesponders were 468+-346 and 783+-346mIU/ml respectively with significant differences between two groups (P=0.001). This study demonstrate moderately increase antibody production in the majority of vaccines with single supplementary vaccine. (author)

Simulation of the capture process in the Fermilab Booster

International Nuclear Information System (INIS)

Stahl, S.; Ankenbrandt, C.

1987-01-01

A progress report on efforts to understand and improve adiabatic capture in the Fermilab Booster by experiment and simulation is presented. In particular, a new Rf voltage program for capture which ameliorates transverse space-charge effects is described and simulated

OPTIMAL SCHEDULING OF BOOSTER DISINFECTION IN WATER DISTRIBUTION SYSTEMS

Science.gov (United States)

Booster disinfection is the addition of disinfectant at locations distributed throughout a water distribution system. Such a strategy can reduce the mass of disinfectant required to maintain a detectable residual at points of consumption in the distribution system, which may lea...

Simulation of proton RF capture in the AGS Booster

International Nuclear Information System (INIS)

Khiari, F.Z.; Luccio, A.U.; Weng, W.T.

1988-01-01

RF capture of the proton beam in the AGS Booster has been simulated with the longitudinal phase-space tracking code ESME. Results show that a capture in excess of 95% can be achieved with multiturn injection of a chopped beam

Synchronization of the Zero Gradient Synchrotron (ZGS) and the fast-cycling booster II injector

International Nuclear Information System (INIS)

Rauchas, A.V.

1977-01-01

The planned method of booster injection into the ZGS requires the stacking of two booster beam bunches into the radial betatron phase space of the ZGS and necessitates precise synchronization of the two accelerators during the injection period. The requirement of maintaining independent radio-frequency (rf) steering control does not allow the frequencies of both accelerators to be locked. A synchronizer was developed which detects a coincidence zero crossing of the two rf's, anticipates the next coincidence, and at that time, generates trigger pulses for the booster extraction and ZGS injection systems. It also maintains control of the sequence in which the total phase space area of the ZGS is loaded. Synchronizer accuracy is obtained by using high speed digital logic circuits. Design considerations and system operation are discussed

Pengaruh Tandem Booster TNT Terhadap Kecepatan Detonasi Campuran Bahan Peledak Tepung Kalium Klorat, Sulfur Dan Aluminium Sebagai Bahan Peldak High Explosive

OpenAIRE

Tarigan, Tarsim

2010-01-01

There are a research on velocity of detonation explosives from Improvised Bomb with potassium chlorate, sulfur and aluminum with a composition of 65:20:15% (weight / weight), 70 mesh, galvanized pipes and containers with some blasting mechanism, starts with an explosion that ignite by a improvise detonator, factory detonator without a booster, factory detonator with a tandem booster TNT, and TNT booster modifications by adding a layer of Pb plate and make a cavity between the main booster ch...

LMFBR with booster pump in pumping loop

International Nuclear Information System (INIS)

Rubinstein, H.J.

1975-01-01

A loop coolant circulation system is described for a liquid metal fast breeder reactor (LMFBR) utilizing a low head, high specific speed booster pump in the hot leg of the coolant loop with the main pump located in the cold leg of the loop, thereby providing the advantages of operating the main pump in the hot leg with the reliability of cold leg pump operation

Control of Fermilab Booster tunes

International Nuclear Information System (INIS)

Johnson, R.P; Meisner, K.; Sandberg, B.

1977-01-01

Control of the radial and vertical tunes of the booster is implemented using ramped correction quadrupoles. Minor modifications to the power supply cards for the 48 (previously) dc correction quadrupoles allow ''the tunes'' to be continuously programmed or held constant throughout the 33 ms acceleration cycle. This capability is in addition to the usual use of these quadrupoles to be independently varied to correct for harmonic distortions in the lattice. An automatic computer program measures and displays the tunes vs. time in the cycle to monitor performance and to allow the ramps to be adjusted by the machine operator

One-year post-primary antibody persistence and booster immune ...

African Journals Online (AJOL)

One-year post-primary antibody persistence and booster immune response to a DTaP-IPV//PRP~T vaccine (Pentaxim) given at 18 - 19 months of age in South African children primed at 6, 10 and 14 weeks of age with the same vaccine.

47 CFR 90.219 - Use of signal boosters.

Science.gov (United States)

2010-10-01

... to operate radio systems in the frequency bands above 150 MHz may employ signal boosters at fixed... fill in only weak signal areas and cannot extend the system's normal signal coverage area. (b) Class A... effective radiated power (ERP) of the unit to a maximum of 5 watts under all conditions. Class B broadband...

Simulation of the capture process in the Fermilab Booster

International Nuclear Information System (INIS)

Stahl, S.; Ankenbrandt, C.

1987-09-01

A progress report on efforts to understand and improve adiabatic capture in the Fermilab Booster by experiment and simulation is presented. In particular, a new RF voltage program for capture which ameliorates transverse space-charge effects is described and simulated. 7 refs., 4 figs

Chromatic perturbation and resonance analysis for the AGS-Booster

International Nuclear Information System (INIS)

Parsa, Z.

1987-01-01

The authors investigated the nonlinear effects with the emphasis on nonlinear resonances. They present some of their findings, (e.g. the structure resonances; stop-bandwidths, etc.) for the AGS-Booster Lattice using program HARMON. Comparison with the results obtained from the algorithm ''NONLIN'' is presented

Analysis of magnetic field measurement results for the AGS Booster magnets

International Nuclear Information System (INIS)

Bleser, E.; Thern, R.

1991-01-01

Magnetic field measurements have been made on nearly 200 conventional magnets that have been installed in the AGS Booster and its associated transfer lines. The measurements were intended to monitor the quality of the magnets being produced and to check the performance of each magnet before installation. The magnetic measurements effort led to certain improvements in the manufacturing process, which ten subsequently produced very good, very uniform magnets. The integrated dipole fields of the 36 booster dipoles are uniform to 1.5 parts in ten thousand. The magnetic measurements indicate that the quadrupoles were manufactured to an accuracy of 3 ten thousandths of an inch, which is better than we can physically measure. 3 refs., 2 figs., 4 tabs

47 CFR 101.151 - Use of signal boosters.

Science.gov (United States)

2010-10-01

... authorized to operate multiple address systems in the 928-929/952-960 MHz and 932-932.5/941-941.5 MHz bands..., or portable station(s). The booster will fill in only weak signal areas and cannot extend the system... automatic gain control circuitry which will limit the total effective radiated power (ERP) of the unit to a...

Measurement of the magnetic field coefficients of particle accelerator magnets

International Nuclear Information System (INIS)

Herrera, J.; Ganetis, G.; Hogue, R.; Rogers, E.; Wanderer, P.; Willen, E.

1989-01-01

An important aspect in the development of magnets to be used in particle accelerators is the measurement of the magnetic field in the beam aperture. In general it is necessary to measure the harmonic multipoles in the dipole, quadrupole, and sextupole magnets for a series of stationary currents (plateaus). This is the case for the Superconducting Super Collider (SSC) which will be ramped to high field over a long period (/approximately/1000 sec.) and then remain on the flat top for the duration of the particle collision phase. In contrast to this mode of operation, the Booster ring being constructed for the Brookhaven AGS, will have a fast ramp rate of approximately 10 Hz. The multipole fields for these Booster magnets must therefore be determined ''on the ramp.'' In this way the effect of eddy currents will be taken into account. The measurement system which we will describe in this paper is an outgrowth of that used for the SSC dipoles. It has the capability of measuring the field multipoles on both a plateau or during a fast ramp. In addition, the same basic coil assembly is used to obtain the magnetic multipoles in dipole, quadrupole, and sextupole magnets. 2 refs., 3 figs., 1 tab

Hepatitis B virus vaccination booster does not provide additional protection in adolescents: a cross-sectional school-based study.

Science.gov (United States)

Chang, Yung-Chieh; Wang, Jen-Hung; Chen, Yu-Sheng; Lin, Jun-Song; Cheng, Ching-Feng; Chu, Chia-Hsiang

2014-09-23

Current consensus does not support the use of a universal booster of hepatitis B virus (HBV) vaccine because there is an anamnestic response in almost all children 15 years after universal infant HBV vaccination. We aimed to provide a booster strategy among adolescents as a result of their changes in lifestyle and sexual activity. This study comprised a series of cross-sectional serological surveys of HBV markers in four age groups between 2004 and 2012. The seropositivity rates of hepatitis B surface antigen (HBsAg) and its reciprocal antibody (anti-HBs) for each age group were collected. There were two parts to this study; age-specific HBV seroepidemiology and subgroup analysis, including effects of different vaccine types, booster response for immunogenicity at 15 years of age, and longitudinal follow-up to identify possible additional protection by HBV booster. Within the study period, data on serum anti-HBs and HBsAg in a total of 6950 students from four age groups were collected. The overall anti-HBs and HBsAg seropositivity rates were 44.3% and 1.2%, respectively. The anti-HBs seropositivity rate in the plasma-derived subgroup was significantly higher in both 15- and 18-year age groups. Overall response rate in the double-seronegative recipients at 15 years of age was 92.5% at 6 weeks following one recombinant HBV booster dose. Among the 24 recipients showing anti-HBs seroconversion at 6 weeks after booster, seven subjects (29.2%) had lost their anti-HBs seropositivity again within 3 years. Increased seropositivity rates and titers of anti-HBs did not provide additional protective effects among subjects comprehensively vaccinated against HBV in infancy. HBV booster strategy at 15 years of age was the main contributor to the unique age-related phenomenon of anti-HBs seropositivity rate and titer. No increase in HBsAg seropositivity rates within different age groups was observed. Vaccination with plasma-derived HBV vaccines in infancy provided higher

Effectiveness of Humidification with Heat and Moisture Exchanger-booster in Tracheostomized Patients.

Science.gov (United States)

Gonzalez, Isabel; Jimenez, Pilar; Valdivia, Jorge; Esquinas, Antonio

2017-08-01

The two most commonly used types of humidifiers are heated humidifiers and heat and moisture exchange humidifiers. Heated humidifiers provide adequate temperature and humidity without affecting the respiratory pattern, but overdose can cause high temperatures and humidity resulting in condensation, which increases the risk of bacteria in the circuit. These devices are expensive. Heat and moisture exchanger filter is a new concept of humidification, increasing the moisture content in inspired gases. This study aims to determine the effectiveness of the heat and moisture exchanger (HME)-Booster system to humidify inspired air in patients under mechanical ventilation. We evaluated the humidification provided by 10 HME-Booster for tracheostomized patients under mechanical ventilation using Servo I respirators, belonging to the Maquet company and Evita 4. There was an increase in the inspired air humidity after 1 h with the humidifier. The HME-Booster combines the advantages of heat and moisture exchange minimizing the negatives. It increases the amount of moisture in inspired gas in mechanically ventilated tracheostomized patients. It is easy and safe to use. The type of ventilator used has no influence on the result.

The low energy booster project status

International Nuclear Information System (INIS)

Tuttle, G.W.

1993-05-01

In order to achieve the required injection momentum, the Superconducting Super Collider (SSC) has an accelerator chain comprised of a Linear Accelerator and three synchrotrons. The Low Energy Booster (LEB) is the first synchrotron in this chain. The LEB project has made significant progress in the development of major subsystems and conventional construction. This paper briefly reviews the performance requirements of the LEB and describes significant achievements in each of the major subsystem areas. Highlighted among these achievements are the LEB foreign collaborations with the Budker Institute of Nuclear Physics (BINP) located in Novosibirsk, Russia

Modeling of the YALINA booster facility by the Monte Carlo code MONK

International Nuclear Information System (INIS)

Talamo, A.; Gohar, Y.; Kondev, F.; Kiyavitskaya, H.; Serafimovich, I.; Bournos, V.; Fokov, Y.; Routkovskaya, C.

2007-01-01

The YALINA-Booster facility has been modeled according to the benchmark specifications defined for the IAEA activity without any geometrical homogenization using the Monte Carlo codes MONK and MCNP/MCNPX/MCB. The MONK model perfectly matches the MCNP one. The computational analyses have been extended through the MCB code, which is an extension of the MCNP code with burnup capability because of its additional feature for analyzing source driven multiplying assemblies. The main neutronics arameters of the YALINA-Booster facility were calculated using these computer codes with different nuclear data libraries based on ENDF/B-VI-0, -6, JEF-2.2, and JEF-3.1.

Emergency department transport rates of children from the scene of motor vehicle collisions: do booster seats make a difference?

Science.gov (United States)

House, Darlene R; Huffman, Gretchen; Walthall, Jennifer D H

2012-11-01

Motor vehicle collisions (MVCs) are the leading cause of death and disability among children older than 1 year. Many states currently mandate all children between the ages of 4 and 8 years be restrained in booster seats. The implementation of a booster-seat law is generally thought to decrease the occurrence of injury to children. We hypothesized that appropriate restraint with booster seats would also cause a decrease in emergency department (ED) visits compared with children who were unrestrained. This is an important measure as ED visits are a surrogate marker for injury. The main purpose of this study was to look at the rate of ED visits between children in booster seats compared with those in other or no restraint systems involved in MVCs. Injury severity was compared across restraint types as a secondary outcome of booster-seat use after the implementation of a state law. A prospective observational study was performed including all children 4 to 8 years old involved in MVCs to which emergency medical services was dispatched. Ambulance services used a novel on-scene computer charting system for all MVC-related encounters to collect age, sex, child-restraint system, Glasgow Coma Scale score, injuries, and final disposition. One hundred fifty-nine children were studied with 58 children (35.6%) in booster seats, 73 children in seatbelts alone (45.2%), and 28 children (19.1%) in no restraint system. 76 children (47.7%), 74 by emergency medical services and 2 by private vehicle, were transported to the ED with no significant difference between restraint use (P = 0.534). Utilization of a restraint system did not significantly impact MVC injury severity. However, of those children who either died (n = 2) or had an on-scene decreased Glasgow Coma Scale score (n = 6), 75% (6/8) were not restrained in a booster seat. The use of booster-seat restraints does not appear to be associated with whether a child will be transported to the ED for trauma evaluation.

Standardized error severity score (ESS) ratings to quantify risk associated with child restraint system (CRS) and booster seat misuse.

Science.gov (United States)

Rudin-Brown, Christina M; Kramer, Chelsea; Langerak, Robin; Scipione, Andrea; Kelsey, Shelley

2017-11-17

Although numerous research studies have reported high levels of error and misuse of child restraint systems (CRS) and booster seats in experimental and real-world scenarios, conclusions are limited because they provide little information regarding which installation issues pose the highest risk and thus should be targeted for change. Beneficial to legislating bodies and researchers alike would be a standardized, globally relevant assessment of the potential injury risk associated with more common forms of CRS and booster seat misuse, which could be applied with observed error frequency-for example, in car seat clinics or during prototype user testing-to better identify and characterize the installation issues of greatest risk to safety. A group of 8 leading world experts in CRS and injury biomechanics, who were members of an international child safety project, estimated the potential injury severity associated with common forms of CRS and booster seat misuse. These injury risk error severity score (ESS) ratings were compiled and compared to scores from previous research that had used a similar procedure but with fewer respondents. To illustrate their application, and as part of a larger study examining CRS and booster seat labeling requirements, the new standardized ESS ratings were applied to objective installation performance data from 26 adult participants who installed a convertible (rear- vs. forward-facing) CRS and booster seat in a vehicle, and a child test dummy in the CRS and booster seat, using labels that only just met minimal regulatory requirements. The outcome measure, the risk priority number (RPN), represented the composite scores of injury risk and observed installation error frequency. Variability within the sample of ESS ratings in the present study was smaller than that generated in previous studies, indicating better agreement among experts on what constituted injury risk. Application of the new standardized ESS ratings to installation

Pertussis circulation has increased T-cell immunity during childhood more than a second acellular booster vaccination in Dutch children 9 years of age.

Directory of Open Access Journals (Sweden)

Rose-Minke Schure

Full Text Available UNLABELLED: Here we report the first evaluation of T-cell responses upon a second acellular pertussis booster vaccination in Dutch children at 9 years of age, 5 years after a preschool booster vaccination. Blood samples of children 9 years of age were studied longitudinally until 1 year after the second aP booster and compared with those after the first aP booster in children 4 and 6 years of age from a cross-sectional study. After stimulation with pertussis-vaccine antigens, Th1, Th2 and Th17 cytokine responses were measured and effector memory cells (CCR7-CD45RA- were characterized by 8-colour FACS analysis. The second aP booster vaccination at pre-adolescent age in wP primed individuals did increase pertussis-specific Th1 and Th2 cytokine responses. Noticeably, almost all T-cell responses had increased with age and were already high before the booster vaccination at 9 years of age. The enhancement of T-cell immunity during the 5 year following the booster at 4 years of age is probably caused by natural boosting due to the a high circulation of pertussis. However, the incidence of pertussis is high in adolescents and adults who have only received the Dutch wP vaccine during infancy and no booster at 4 years of age. Therefore, an aP booster vaccination at adolescence or later in these populations might improve long-term immunity against pertussis and reduce the transmission to the vulnerable newborns. TRIAL REGISTRATION: Controlled-Trials.com ISRCTN64117538.

Results from the AGS Booster transverse damper

International Nuclear Information System (INIS)

Russo, D.; Brennan, M.; Meth, M.; Roser, T.

1993-01-01

To reach the design intensity of 1.5 x 10 13 protons per pulse in the AGS Booster, transverse coupled bunch instabilities with an estimated growth rate of 1500s -1 have to be dampened. A prototype transverse damper has been tested successfully using a one turn digital delay and closed orbit suppression implemented in a programmable gate array. An updated damper, which includes an algorithm to optimize damping for a changing betatron rune, will also be presented

Booster HBV vaccination; is it really necessary? | Alavian | Egyptian ...

African Journals Online (AJOL)

Egyptian Journal of Pediatric Allergy and Immunology (The). Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 9, No 2 (2011) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register. Booster HBV vaccination; is it ...

Power Supply of the Booster Magnets for the ILSF Synchrotron

Directory of Open Access Journals (Sweden)

O Ahmadi

2017-08-01

Full Text Available The Iranian Light Source Facility (ILSF booster main specifications including 250 ms ramp up, 2Hz repetition rate, and quasi-sinusoidal wave shape, up to this point have been the basis for calculations. Each family of magnets including Dipole, Quadrupole and Sextupoles will feed by individual power supply. In order to maintain constant transverse tunes and chromaticity while the beam is accelerated, quadrupole and sextupole magnet currents must closely track the current in the dipole magnets. In booster rings, feeding the high inductance load, tracking of Quadrupole and sextupole magnets, reducing output current fluctuation and having a precise high bandwidth current regulation system are particular challenges. In order to meet the requirements, it is necessary to have a fully digital controller to achieve a fast regulation system. The prototype power supply and its test results are described in this paper  

The AGS Booster vacuum systems

International Nuclear Information System (INIS)

Hseuh, H.C.

1989-01-01

The AGS Booster is a synchrotron for the acceleration of both protons and heavy ions. The design pressure of low 10 -11 mbar is required to minimize beam loss of the partially stripped heavy ions. To remove contaminants and to reduce outgassing, the vacuum chambers and the components located in them will be chemically cleaned, vacuum fired, baked then treated with nitric oxide. The vacuum sector will be insitu baked to a minimum of 200 degree C and pumped by the combination of sputter ion pumps and titanium sublimation pumps. This paper describes the design and the processing of this ultra high vacuum system, and the performance of some half-cell vacuum chambers. 9 refs., 7 figs

REDUCING THE BOOSTER STATIONS ENERGY CONSUMPTION BY WAY OF ELIMINATING OVERPRESSURE IN THE WATER SUPPLY NETWORK

Directory of Open Access Journals (Sweden)

G. N. Zdor

2015-01-01

Full Text Available The energy efficiency improvement of the city housing-and-utilities infrastructure and watersupply and water-disposal systems poses an occurrent problem. The water-supply systems energy consumption sizable share falls on the pump plants. The article deals with the issues of the operating regime management of the existing booster stations equipped with a group of pumping units regulated with frequency converters. One of the optimization directions of their energy consumption is the reduction of over-pressure in the water-distribution network and its sustentation within the regulatory values. The authors offer the structure and methodology of the data collection-and-analysis automated system utilization for revealing and eliminating the overpressure in the water-supply network. This system is designed for the group management of booster-stations operating regimes on the ground of data obtained from the pressure controlling devices at the consumers. The data exchange in the system is realized via GSM.The paper presents results of the tests carried out at the booster stations in some major cities of the Republic of Belarus. The authors analyze dependence of overpressure in the network on the methods of the plant output pressure sustentation (daily graph or constant pressure. The authors study the elimination effect of over-pressure in the water distribution network on changing the booster station pumping units operation regimes. The study shows that eliminating over pressure in the water distributing network leads to lowering the booster station pressure. This in its turn decreases its energy consumption by 15–20 % depending on the over pressure fixed level.

Beam position monitoring in the AGS Linac to Booster transfer line

International Nuclear Information System (INIS)

Shea, T.J.; Brodowski, J.; Witkover, R.

1991-01-01

A beam position monitor system has been developed and used in the commissioning of Brookhaven's Linac to Booster transfer line. This line transports a chopped, RF modulated H- beam from the 200 MeV Linac to the AGS Booster. Over a 15dB dynamic range in beam current, the position monitor system provides a real-time, normalized position signal with an analog bandwidth of about 20 MHz. Seven directional coupler style pickups are installed in the line with each pickup sensing both horizontal and vertical position. Analog processing electronics are located in the tunnel and incorporate the amplitude modulation to phase modulation normalization technique. To avoid interference from the 200 MHz linac RF system, processing is performed at 400 MHz. This paper provides a system overview and report results from the commissioning experience

Electron cooling system in the booster synchrotron of the HIAF project

Energy Technology Data Exchange (ETDEWEB)

Mao, L.J., E-mail: maolijun@impcas.ac.cn [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Yang, J.C.; Xia, J.W.; Yang, X.D.; Yuan, Y.J.; Li, J.; Ma, X.M.; Yan, T.L.; Yin, D.Y.; Chai, W.P.; Sheng, L.N. [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Shen, G.D.; Zhao, H.; Tang, M.T. [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Graduate University of Chinese Academy of Sciences, Beijing 100049 (China)

2015-06-21

The High Intensity heavy ion Accelerator Facility (HIAF) is a new accelerator complex under design at the Institute of Modern Physics (IMP). The facility is aiming at the production of high intensity heavy ion beams for a wide range of experiments in high energy density physics, nuclear physics, atomic physics and other applications. It consists of a superconducting electron-cyclotron-resonance ion source and an intense proton ion source, a linear accelerator, a 34 Tm booster synchrotron ring, a 43 Tm multifunction compression synchrotron ring, a 13 Tm high precision spectrometer ring and several experimental terminals. A magnetized electron cooling device is supposed to be used in the booster ring for decreasing the transverse emittance of injected beams. The conceptual design and main parameters of this cooler are presented in this paper.

Development of hydraulic brake actuator for active brake control; Active brake seigyoyo yuatsu booster no kaihatsu

Energy Technology Data Exchange (ETDEWEB)

Konishi, Y; Hattori, M. Sugisawa, M.; Nishii, M [Aisin Seiki Co. Ltd., Aichi (Japan)

1997-10-01

Recently, application of active brake control systems of the vehicle are increasing. (Vehicle stability control, Panic brake assist ) We have developed a new hydraulic brake actuator for active brake control systems. New hydraulic brake actuator is composed of the three parts. (Hydraulic booster unit, Power supply unit, Control valve unit) This report describes the construction of the new hydraulic booster unit. 2 refs., 10 figs.

Exercise, Manual Therapy, and Booster Sessions in Knee Osteoarthritis: Cost-Effectiveness Analysis From a Multicenter Randomized Controlled Trial.

Science.gov (United States)

Bove, Allyn M; Smith, Kenneth J; Bise, Christopher G; Fritz, Julie M; Childs, John; Brennan, Gerard P; Abbott, J Haxby; Fitzgerald, G Kelley

2018-01-01

Limited information exists regarding the cost-effectiveness of rehabilitation strategies for individuals with knee osteoarthritis (OA). The study objective was to compare the cost-effectiveness of 4 different combinations of exercise, manual therapy, and booster sessions for individuals with knee OA. This economic evaluation involved a cost-effectiveness analysis performed alongside a multicenter randomized controlled trial. The study took place in Pittsburgh, Pennsylvania; Salt Lake City, Utah; and San Antonio, Texas. The study participants were 300 individuals taking part in a randomized controlled trial investigating various physical therapy strategies for knee OA. Participants were randomized into 4 treatment groups: exercise only (EX), exercise plus booster sessions (EX+B), exercise plus manual therapy (EX+MT), and exercise plus manual therapy and booster sessions (EX+MT+B). For the 2-year base case scenario, a Markov model was constructed using the United States societal perspective and a 3% discount rate for costs and quality-adjusted life years (QALYs). Incremental cost-effectiveness ratios were calculated to compare differences in cost per QALY gained among the 4 treatment strategies. In the 2-year analysis, booster strategies (EX+MT+B and EX+B) dominated no-booster strategies, with both lower health care costs and greater effectiveness. EX+MT+B had the lowest total health care costs. EX+B cost ${\\$}$1061 more and gained 0.082 more QALYs than EX+MT+B, for an incremental cost-effectiveness ratio of ${\\$}$12,900/QALY gained. The small number of total knee arthroplasty surgeries received by individuals in this study made the assessment of whether any particular strategy was more successful at delaying or preventing surgery in individuals with knee OA difficult. Spacing exercise-based physical therapy sessions over 12 months using periodic booster sessions was less costly and more effective over 2 years than strategies not containing booster sessions for

Maintaining the potential of a psycho-educational program: efficacy of a booster session after an intervention offered family caregivers at disclosure of a relative's dementia diagnosis.

Science.gov (United States)

Ducharme, Francine; Lachance, Lise; Lévesque, Louise; Zarit, Steven Howard; Kergoat, Marie-Jeanne

2015-01-01

Booster sessions as a means of maintaining the benefits of psycho-educational programs have received little attention in caregiving research. Caregivers were offered a booster session following participation in a program entitled Learning to Become a Family Caregiver (LBFC) intended to facilitate transition to the caregiver role after diagnostic disclosure of dementia in a relative. The 90-minute booster session served to review program content and afforded the opportunity to discuss and practice learned skills. This study sought to test the efficacy of the booster session in maintaining or recovering program effects at six months post-program. Participants in the program were randomly assigned to a group that received the booster session (n = 31) or a group that did not (n = 29). A third control group was also formed, which continued to receive only the usual care provided in memory clinics. Eligible participants - French-speaking primary caregivers of a relative diagnosed with Alzheimer's in the past nine months - were recruited in memory clinics in Quebec (Canada). Participants were blindly assessed before randomization and six months after the booster session on outcomes associated with a healthy role transition. Prediction analyses revealed one significant positive effect of the booster session: emergence of preparedness to provide care. Moreover, with or without the booster session, the program continued to have a positive effect on psychological distress and contributed to the emergence of self-efficacy in dealing with caregiving situations. The booster session had no significant effect on knowledge of services, planning for future care needs, use of reframing as a coping strategy, perceived informal support, and family conflicts. The limited effect observed is discussed in terms of the booster session's content and intensity. Recommendations are made for designing future research on the effect of booster sessions, including the importance of including a

Design and testing of the AGS Booster BPM detector

International Nuclear Information System (INIS)

Thomas, R.; Ciardullo, D.J.; Van Zwienen, W.

1991-01-01

The AGS Booster beam position monitor system must accurately measure the position of beams and bunches over a wide range of intensity. The frequency of operation must also cover a wide range (600 kHz to 4.2 MHz) since the Booster accelerates both protons and heavy ions. Split-cylinder electrodes were chosen to monitor the position of the beam because of their good low frequency response and high linearity. The need to accelerate low-energy partially-stripped heavy ions requires the pick-up electrodes (PUEs) to operate in a 3 x 10 -11 torr vacuum. The PUEs are to measure the beam position to an absolute accuracy of ±0.5 mm and must therefore be mechanically stable despite the requirements that they be vacuum fired at 950 degree C and baked periodically to 300 degree C. This presentation describes both the mechanical design of the PUEs and the automated test procedure used to ensure the stability, accuracy, and linearity of each unit. 3 refs., 5 figs

Low Energy Electron Cooler for NICA Booster

CERN Document Server

Denisov, A P

2017-01-01

BINP has developed an electron cooler to increase the ion accumulation efficiency in the NICA (Nuclotron-based Ion Collider fAcility) heavy ion booster (JINR, Dubna). Adjustment of the cooler magnetic system provides highly homogeneous magnetic field in the cooling section B trans/B long ≤ 4∙10-5 which is vital for efficient electron cooling. First experiments with an electron beam performed at BINP demonstrated the target DC current of 500 mA and electron energy 6 keV.

Position pickup of the PS Booster

CERN Multimedia

CERN PhotoLab

1975-01-01

The beam position around the 4 rings of the PS Booster (originally 800 MeV, now 1.4 GeV), is measured with electrostatic pickups (PU). They consist of a ceramic cylinder forming part of the vacuum chamber, and, in order to save space, they are located inside the multipole lenses. The inside of the ceramic is coated with a metallic layer, into which the form of the electrodes was cut by computer-controlled micro-sandblasting. Each PU has a pair of horizontal and a pair of vertical electrodes, as well as a separate intensity-sensing circular electrode.

Ultra-short-course booster is effective in recurrent grass pollen-induced allergic rhinoconjunctivitis.

Science.gov (United States)

Pfaar, O; Lang, S; Pieper-Fürst, U; Astvatsatourov, A; Gerich, F; Klimek, L; Kramer, M F; Reydelet, Y; Shah-Hosseini, K; Mösges, R

2018-01-01

A relevant proportion of allergic rhinoconjunctivitis (ARC) patients experience recurrent symptoms after successfully completing allergen immunotherapy (AIT). This prospective, controlled, noninterventional study used internationally standardized instruments to determine the clinical effects of a preseasonal, ultra-short-course booster AIT on clinical outcome parameters. This two-arm study included patients aged ≥12 years with recurrent grass pollen-induced seasonal AR who had completed a successful course of any grass pollen AIT at least 5 years before enrolment. Overall, 56 patients received one preseasonal short-course booster AIT using tyrosine-absorbed grass pollen allergoids containing the adjuvant monophosphoryl lipid A (MPL ® ); 51 control patients received symptomatic medication. The combined symptom and medication score (CSMS) was recorded in the (peak) grass pollen season. Furthermore, concomitant (antiallergic) medication use, the patients' state of health, Mini Rhinoconjunctivitis Quality of Life Questionnaire (MiniRQLQ) results and safety/tolerability of the treatment were assessed. The CSMS in the peak grass pollen season was significantly lower in the booster AIT group (Δ=38.4%, Pallergoids containing the adjuvant MPL ® effectively prevents re-occurrence of symptoms in patients with grass pollen-induced ARC. © 2017 The Authors. Allergy Published by John Wiley & Sons Ltd.

Active immunisation of horses against tetanus including the booster dose and its application.

Science.gov (United States)

Liefman, C E

1981-02-01

Successful active immunisation of horses against tetanus is dependent on a number of factors of which the toxoid preparation used, its method of application and the ability of the individual horse to respond are fundamental. Two immunisation schedules using an aluminium-based toxoid preparation were examined and the protection determined by monitoring the level of antitoxin afforded by each schedule. The results obtained demonstrated that 2 doses of this toxoid are necessary to ensure 12 months protection in all horses. These results are discussed in relation to the factors involved in active immunisation against tetanus. Reference is also made to the occurrence of a transient phase of reduced levels of antitoxin following booster doses of toxoid in immunised horses during which it is considered these horses could become more susceptible to tetanus. The effect of a booster dose on immunised horses was examined and while there can be a reduction in the level of antitoxin in some immunised horses following this dose its effect is minimal, short-lived and for all practical purposes can be disregarded. The application of the booster dose in practice is also discussed.

Preparations for Upgrading the RF Systems of the PS Booster

CERN Document Server

Albright, Simon; Shaposhnikova, Elena

2016-01-01

The accelerators of the LHC injector chain need to be upgraded to provide the HL-LHC beams. The PS Booster, the first synchrotron in the LHC injection chain, uses three different RF systems (first, second and up to tenth harmonic) in each of its four rings. As part of the LHC Injector Upgrade the current ferrite RF systems will be replaced with broadband Finemet cavities, increasing the flexibility of the RF system. A Finemet test cavity has been installed in Ring 4 to investigate its effect on machine performance, especially beam stability, during extensive experimental studies. Due to large space charge impedance Landau damping is lost through most of the cycle in single harmonic operation, but is recovered when using the second harmonic and controlled longitudinal emittance blow-up. This paper compares beam parameters during acceleration with and without the Finemet test cavity. Comparisons were made using beam measurements and simulations with the BLonD code based on a full PS Booster impedance model. Thi...

Perpendicular biased ferrite tuned RF cavity for the TRIUMF KAON Factory booster ring

International Nuclear Information System (INIS)

Poirier, R.L.; Enegren, T.; Haddock, C.

1989-03-01

The rf cavity for the booster ring requires a frequency swing of 46 MHz to 62 MHz at a repetition rate of 50 Hz. The possibility of using the LANL booster cavity design with a yttrium garnet ferrite tuner biased perpendicular to the rf field, in the longitudinal direction, is being investigated. In order to minimize the stray magnetic biasing field on the beam axis, an alternative scheme similar to the design being proposed for the LANL main ring cavity in which the ferrite is perpendicular biased in the radial direction, is being considered. The behaviour of the rf cavity and the magnetizing circuit for both designs are discussed

A new one-man submarine is tested as vehicle for solid rocket booster retrieval

Science.gov (United States)

2000-01-01

- The one-man submarine known as DeepWorker 2000 is tested in Atlantic waters near Cape Canaveral, Fla. Nearby are divers; inside the sub is the pilot, Anker Rasmussen. The sub is being tested on its ability to duplicate the sometimes hazardous job United Space Alliance (USA) divers perform to recover the expended boosters in the ocean after a launch. The boosters splash down in an impact area about 140 miles east of Jacksonville and after recovery are towed back to KSC for refurbishment by the specially rigged recovery ships. DeepWorker 2000 will be used in a demonstration during retrieval operations after the upcoming STS-101 launch. The submarine pilot will demonstrate capabilities to cut tangled parachute riser lines using a manipulator arm and attach a Diver Operator Plug to extract water and provide flotation for the booster. DeepWorker 2000 was built by Nuytco Research Ltd., North Vancouver, British Columbia. It is 8.25 feet long, 5.75 feet high, and weighs 3,800 pounds. USA is a prime contractor to NASA for the Space Shuttle program.

Design and optimization of a large flow rate booster pump in SWRO energy recovery system

International Nuclear Information System (INIS)

Lai, Z N; Wu, P; Wu, D Z; Wang, L Q

2013-01-01

Seawater reverse osmosis (SWRO) is a high energy-consumption industry, so energy efficiency is an important issue. Energy recovery systems, which contain a pressure exchanger and a booster pump, are widely used in SWRO plants. As a key part of energy recovery system, the difficulty of designing booster pumps lies in high inlet pressure, high medium causticity and large flow rate. High inlet pressure adds difficulties to seal design, and large flow rate and high efficiency requirement bring high demand for hydraulic design. In this paper, a 625 m 3 /h booster pump is designed and optimized according to the CFD (Computational Fluid Dynamics) simulation results. The impeller and volute is well designed, a new type of high pressure mechanical seal is applied and axial force is well balanced. After optimization based on blade redesign, the efficiency of the pump was improved. The best efficiency reaches more than 85% at design point according to the CFD simulation result

Design and optimization of a large flow rate booster pump in SWRO energy recovery system

Science.gov (United States)

Lai, Z. N.; Wu, P.; Wu, D. Z.; Wang, L. Q.

2013-12-01

Seawater reverse osmosis (SWRO) is a high energy-consumption industry, so energy efficiency is an important issue. Energy recovery systems, which contain a pressure exchanger and a booster pump, are widely used in SWRO plants. As a key part of energy recovery system, the difficulty of designing booster pumps lies in high inlet pressure, high medium causticity and large flow rate. High inlet pressure adds difficulties to seal design, and large flow rate and high efficiency requirement bring high demand for hydraulic design. In this paper, a 625 m3/h booster pump is designed and optimized according to the CFD (Computational Fluid Dynamics) simulation results. The impeller and volute is well designed, a new type of high pressure mechanical seal is applied and axial force is well balanced. After optimization based on blade redesign, the efficiency of the pump was improved. The best efficiency reaches more than 85% at design point according to the CFD simulation result.

Project of Ariane 5 LV family advancement by use of reusable fly-back boosters (named “Bargouzine”)

Science.gov (United States)

Sumin, Yu.; Bonnal, Ch.; Kostromin, S.; Panichkin, N.

2007-12-01

The paper concerns possible concept variants of a partially reusable Heavy-Lift Launch Vehicle derived from the advanced basic launcher (Ariane-2010) by means of substitution of the EAP Solid Rocket Boosters for a Reusable Starting Stage consisting two Liquid-propellant Reusable Fly-Back Boosters called "Bargouzin". This paper describes the status of the presently studied RFBB concepts during its three phases. The first project phase was dedicated to feasibility expertise of liquid-rocket reusable fly-back boosters ("Baikal" type) utilization for heavy-lift space launch vehicle. The design features and main conclusions are presented. The second phase has been performed with the purpose of selection of preferable concept among the alternative ones for the future Ariane LV modernization by using RFBB instead of EAP Boosters. The main requirements, logic of work, possible configuration and conclusion are presented. Initial aerodynamic, ballistic, thermoloading, dynamic loading, trade-off and comparison analysis have been performed on these concepts. The third phase consists in performing a more detailed expertise of the chosen LV concept. This part summarizes some of the more detailed results related to flight performance, system mass, thermoprotection system, aspects of technologies, ground complex modification, comparison analyses and conclusion.

Does a booster intervention augment the preventive effects of an abbreviated version of the coping power program for aggressive children?

Science.gov (United States)

Lochman, John E; Baden, Rachel E; Boxmeyer, Caroline L; Powell, Nicole P; Qu, Lixin; Salekin, Karen L; Windle, Michel

2014-01-01

Booster interventions have been presumed to be important methods for maintaining the effects of evidence-based programs for children with behavioral problems, but there has been remarkably little empirical attention to this assumption. The present study examines the effect of a child-oriented booster preventive intervention with children who had previously received an abbreviated version (24 child sessions, 10 parent sessions) of the Coping Power targeted prevention program. Two hundred and forty-one children (152 boys, 89 girls) were screened as having moderate to high levels of aggressive behavior in 4th grade, then half were randomly assigned to receive the abbreviated Coping Power program in 5th grade, and half of the preventive intervention children were then randomly assigned to a Booster condition in 6th grade. The Booster sessions consisted of brief monthly individual contacts, and were primarily with the children. Five assessments across 4 years were collected from teachers, providing a three-year follow-up for all children who participated in the project. Results indicated that the abbreviated Coping Power program (one-third shorter than the full intervention) had long-term effects in reducing children's externalizing problem behaviors, proactive and reactive aggression, impulsivity traits and callous-unemotional traits. The Booster intervention did not augment these prevention effects. These findings indicate that a briefer and more readily disseminated form of an evidence-based targeted preventive intervention was effective. The findings have potential implications for policy and guidelines about possible intervention length and booster interventions.

A Linac afterburner to supercharge the Fermilab booster

International Nuclear Information System (INIS)

Ankenbrandt M, Charles email = popovic@fnal.gov

2002-01-01

A Linac Afterburner is proposed to raise the energy of the beam injected into the Femrilab Booster from 400 MeV to about 600 MeV, thereby alleviating the longitudinal and transverse space-charge effects at low energy that currently limit its performance. The primary motivation is to increase the integrated luminosity of the Tevatron Collider in Run II, but other future programs would also recap substantial benefits. The estimated cost is $23M

Implementation of electron beam position measurement algorithm and embedded web server using MCS-51 microcontroller for Booster Synchrotron

International Nuclear Information System (INIS)

Shrivastava, B.B.; Chouhan, Manish; Puntambekar, T.A.; Tiwari, A.N.

2015-01-01

The Booster Synchrotron at RRCAT caters as Injector Machine for Indus-1 and Indus-2 with the repetition rate of 1Hz. In Booster Synchrotron, energy of electron bunches are increased from 20 MeV to 450 MeV (in ∼ 280 ms) and 550 MeV (in ∼ 340 ms ) for Indus-1 and Indus-2 respectively. An algorithm for microcontroller based beam position measurement system has been developed for the Booster Synchrotron to measure the fast changes in the beam position of electron bunches during energy ramping. In this paper, software implementation in microcontroller and its optimization to achieve beam position update rate of 1 kHz is discussed. (author)

Numerical model for thermoeconomic diagnosis in commercial transcritical/subcritical booster refrigeration systems

International Nuclear Information System (INIS)

Ommen, Torben; Elmegaard, Brian

2012-01-01

Highlights: ► A transcritical booster refrigeration plant is modelled. ► We examine changes in cost flow at different operation parameters. ► The use of characteristic curves for diagnosis is studied. - Abstract: Transcritical/subcritical booster refrigeration systems are increasingly installed and used in Danish supermarkets. The systems operate in both transcritical and subcritical conditions dependent on the heat rejection performance and the ambient conditions. The plant consists of one refrigerant cycle supplying refrigerant for evaporators in both chilled and frozen display cases. In the paper, thermoeconomic theory is used to establish the cost of cooling at each individual temperature level based on operating costs. With a high amount of operating systems, faulty operation becomes an economic, and environmental, interest. A general solution for evaluation of these systems is considered, with the objective to reduce cost and power consumption of malfunctioning equipment in operation. An analysis of the use of thermoeconomic diagnosis methods is required, as these methods may prove applicable. To accommodate the analysis, a numerical model of a transcritical booster refrigeration plant is considered in this paper. Additionally the characteristic curves method is applied to the high pressure compressor unit of the refrigeration plant. The approach successfully determine whether an anomaly is intrinsic or induced in the component when no uncertainties are introduced in the steady state model.

The injection and extraction of SSRF booster

International Nuclear Information System (INIS)

Li Yuan; Li Haohu; Liu Guimin; Li Deming

2008-01-01

The layout of injection and extraction system were introduced in this paper. The horizontal and vertical injection acceptance are about 23 πmm·mrad and 37 πmm·mrad, respectively, while emittance of the injected beam is 9 πmm·mrad (3σ). This ensures the high injection efficiency. Three slow kickers can form a good bump. The inside position of the entrance of septum is set to 15 mm, where the bumped beam and the extraction beam are 10 mm and 22 mm, respectively, far from the booster central orbit. (authors)

The PS Booster's ejection kicker: full house.

CERN Multimedia

CERN PhotoLab

1971-01-01

The modules of the Booster's four-storied full-aperture kicker pretty much fill their vacuum tank (front cover removed). In the original 800 MeV version, the delay-type modules were pulsed at 30 kV from a Pulse-Forming-Network (PFN), yielding a field risetime as short as 60 ns. The fieldstrength was 0.1 T at a current of 1200 A. The modules are made from steel plates and ferrite slabs. The ferrite's high initial outgassing rate presented a serious vacuum problem for a long time.

Multipole stack for the 4 rings of the PS Booster

CERN Multimedia

CERN PhotoLab

1976-01-01

The PS Booster (originally 800 MeV, now 1.4 GeV) saw first beam in 1972, routine operation began in 1973. The strive for ever higher intensities required the addition of multipoles. Manufacture of 8 stacks of multipoles was launched in 1974, for installation in 1976. For details, see 7511120X.

RF field control for KAON Factory booster cavities

International Nuclear Information System (INIS)

Craig, S.T.; de Jong, M.S.

1990-11-01

A conceptual design is developed for control of the KAON Factory Booster rf accelerating fields. This design addresses control of cavity: tuning, voltage amplitude, and voltage phase angle. Time-domain simulations were developed to evaluated the proposed controllers. These simulations indicated that adequate tuning performance can be obtained with the combination of adaptive feed-forward and proportional feedback control. Voltage amplitude and voltage phase can be adequately controlled using non-adaptive feedforward and proportional feedback control

Beam Diagnosis and Lattice Modeling of the Fermilab Booster

International Nuclear Information System (INIS)

Huang, Xiaobiao

2005-01-01

A realistic lattice model is a fundamental basis for the operation of a synchrotron. In this study various beam-based measurements, including orbit response matrix (ORM) and BPM turn-by-turn data are used to verify and calibrate the lattice model of the Fermilab Booster. In the ORM study, despite the strong correlation between the gradient parameters of adjacent magnets which prevents a full determination of the model parameters, an equivalent lattice model is obtained by imposing appropriate constraints. The fitted gradient errors of the focusing magnets are within the design tolerance and the results point to the orbit offsets in the sextupole field as the source of gradient errors. A new method, the independent component analysis (ICA) is introduced to analyze multiple BPM turn-by-turn data taken simultaneously around a synchrotron. This method makes use of the redundancy of the data and the time correlation of the source signals to isolate various components, such as betatron motion and synchrotron motion, from raw BPM data. By extracting clean coherent betatron motion from noisy data and separates out the betatron normal modes when there is linear coupling, the ICA method provides a convenient means to measure the beta functions and betatron phase advances. It also separates synchrotron motion from the BPM samples for dispersion function measurement. The ICA method has the capability to separate other perturbation signals and is robust over the contamination of bad BPMs. The application of the ICA method to the Booster has enabled the measurement of the linear lattice functions which are used to verify the existing lattice model. The transverse impedance and chromaticity are measured from turn-by-turn data using high precision tune measurements. Synchrotron motion is also observed in the BPM data. The emittance growth of the Booster is also studied by data taken with ion profile monitor (IPM). Sources of emittance growth are examined and an approach to cure

Yalina booster subcritical assembly performance with low enriched uranium fuel

International Nuclear Information System (INIS)

Talamo, Alberto; Gohar, Yousry

2011-01-01

The YALINA Booster facility is a subcritical assembly located in Minsk, Belarus. The facility has special features that result in fast and thermal neutron spectra in different zones. The fast zone of the assembly uses a lead matrix and uranium fuels with different enrichments: 90% and 36%, 36%, or 21%. The thermal zone of the assembly contains 10% enriched uranium fuel in a polyethylene matrix. This study discusses the performance of the three YALINA Booster configurations with the different fuel enrichments. In order to maintain the same subcriticality level in the three configurations, the number of fuel rods in the thermal zone is increased as the uranium fuel enrichment in the fast zone is decreased. The maximum number of fuel rods that can be loaded in the thermal zone is about 1185. Consequently, the neutron multiplication of the configuration with 21% enriched uranium fuel in the fast zone is enhanced by changing the position of the boron carbide and the natural uranium absorber rods, located between the fast and the thermal zones, to form an annular rather than a square arrangement. (author)

Yalina booster subcritical assembly performance with low enriched uranium fuel

Energy Technology Data Exchange (ETDEWEB)

Talamo, Alberto; Gohar, Yousry, E-mail: alby@anl.gov [Argonne National Laboratory, Lemont, IL (United States)

2011-07-01

The YALINA Booster facility is a subcritical assembly located in Minsk, Belarus. The facility has special features that result in fast and thermal neutron spectra in different zones. The fast zone of the assembly uses a lead matrix and uranium fuels with different enrichments: 90% and 36%, 36%, or 21%. The thermal zone of the assembly contains 10% enriched uranium fuel in a polyethylene matrix. This study discusses the performance of the three YALINA Booster configurations with the different fuel enrichments. In order to maintain the same subcriticality level in the three configurations, the number of fuel rods in the thermal zone is increased as the uranium fuel enrichment in the fast zone is decreased. The maximum number of fuel rods that can be loaded in the thermal zone is about 1185. Consequently, the neutron multiplication of the configuration with 21% enriched uranium fuel in the fast zone is enhanced by changing the position of the boron carbide and the natural uranium absorber rods, located between the fast and the thermal zones, to form an annular rather than a square arrangement. (author)

Effect of oral booster vaccination of rainbow trout against Yersinia ruckeri depends on type of primary immunization

DEFF Research Database (Denmark)

Jaafar, Rzgar M.; Al-Jubury, Azmi; Dalsgaard, Inger

2017-01-01

provided as dip (most effective), bath (less effective) or orally (least effective). Oral immunization may be used as booster after dip but applied as a single oral application it induced merely a slight and statistically non-significant response. It is noteworthy that primary oral immunization followed...... already primed by one of these vaccination methods. Oral vaccination of trout (administering vaccine in feed) is an even more convenient way of presenting antigen to the fish but the effect of an oral booster has not previously been described in detail. The present work describes to what extent protection...... by an oral booster vaccination showed a trend for an even weaker response. It should be investigated if continued exposure to a low antigen concentration - as performed by two oral immunizations - may induce tolerance to the pathogen and thereby leave the fish more vulnerable....

Power flow control using quadrature boosters

Science.gov (United States)

Sadanandan, Sandeep N.

A power system that can be controlled within security constraints would be an advantage to power planners and real-time operators. Controlling flows can lessen reliability issues such as thermal limit violations, power stability problems, and/or voltage stability conditions. Control of flows can also mitigate market issues by reducing congestion on some lines and rerouting power to less loaded lines or onto preferable paths. In the traditional control of power flows, phase shifters are often used. More advanced methods include using Flexible AC Transmission System (FACTS) Controllers. Some examples include Thyristor Controlled Series Capacitors, Synchronous Series Static Compensators, and Unified Power Flow Controllers. Quadrature Boosters (QBs) have similar structures to phase-shifters, but allow for higher voltage magnitude during real power flow control. In comparison with other FACTS controllers QBs are not as complex and not as expensive. The present study proposes to use QBs to control power flows on a power system. With the inclusion of QBs, real power flows can be controlled to desired scheduled values. In this thesis, the linearized power flow equations used for power flow analysis were modified for the control problem. This included modifying the Jacobian matrix, the power error vector, and calculating the voltage injected by the quadrature booster for the scheduled real power flow. Two scenarios were examined using the proposed power flow control method. First, the power flow in a line in a 5-bus system was modified with a QB using the method developed in this thesis. Simulation was carried out using Matlab. Second, the method was applied to a 30-bus system and then to a 118-bus system using several QBs. In all the cases, the calculated values of the QB voltages led to desired power flows in the designated line.

Using Growth Curves To Determine the Timing of the Booster Sessions.

Science.gov (United States)

Hennessy, Michael; Bolan, Gail A.; Hoxworth, Tamara; Iatesta, Michael; Rhodes, Fen; Zenilman, Jonathan M.

1999-01-01

Demonstrates an application of a method for using growth curves to determine the timing of booster sessions to reinforce the cognitive messages or behavior changes of interventions. Uses data from a multisite randomized experiment that compared three counseling and testing methods for preventing sexual disease transmission. Presents…

The harmonic composition of the output voltage of a rectifier unit with a PWM voltage booster converter.

OpenAIRE

ПАНЧЕНКО, В В

2015-01-01

The author investigates a rectifier unit constructed on the basis of cascade connection of the main non-controlled m-pulse rectifier and PWM voltage booster converter. The research presents the analysis of the harmonic composition of the output voltage of a rectifier unit with a PWM voltage booster converter on completely controlled keys. The dependence of the relative harmonic amplitude on the commutation corner is defined. The estimation of a rectifier unit electromagnetic compatibility wit...

New low-level rf system for the Fermilab Booster synchrotron

International Nuclear Information System (INIS)

Kerns, C.; Crisp, J.; Kerns, Q.; Miller, H.

1987-03-01

This paper describes the Booster low-level rf system that was constructed to meet these recently added requirements: (1) synthesizer controlled capture frequency at injection, (2) very low-phase noise over the machine cycle, (3) smooth phase-lock of beam to an external reference frequency and (4) ability to accelerate either a full turn or partial turn of beam

Dipole power supply for National Synchrotron Light Source Booster upgrade

International Nuclear Information System (INIS)

Olsen, R.; Dabrowski, J.; Murray, J.

1992-01-01

The booster at the NSLS is being upgraded from .75 to 2 pulses per second. To accomplish this, new power supplies for the dipole, quadrupole, and sextupole magnets have been designed and are being constructed. This paper will outline the design of the dipole power supply and control system, and will present results obtained thus far

Digital signal array processor for NSLS booster power supply upgrade

International Nuclear Information System (INIS)

Olsen, R.; Dabrowski, J.; Murray, J.

1993-01-01

The booster at the NSLS is being upgraded from 0.75 to 2 pulses per second. To accomplish this, new power supplied for the dipole, quadrupole, and sextupole have been installed. This paper will outline the design and function of the digital signal processor used as the primary control element in the power supply control system

Processing and evaluation of the AGS Booster ultra-high vaccum system

International Nuclear Information System (INIS)

Hseuh, H.C.; Mapes, M.; Schnitzenbaumer, P.; Shen, B.; Sikora, R.; Stattel, P.

1991-01-01

The AGS Booster is a synchrotron for the acceleration of both protons and heavy ions. To minimize the beam loss due to charge exchange of the partially stripped, low Β very heavy ions with the residual gas molecules, pressure of low 10 -11 Torr is required for the 200 m booster ring. To achieve this ultra high vacuum, chemical cleaning, vacuum furnace degassing and insitu bake were employed for all chambers and beam components. Using these procedures, vacuums of low 10 -11 Torr have been routinely achieved during the testing of individual half cells and beam components, and during the commissioning of the vacuum sectors. In this paper, the design and layout of chambers, flanges and bakeout hardware is briefly described. The vacuum processing of different components and the results of bakeout and evaluation are summarized. The experience gained during the construction and commissioning of this ultra-high vacuum system is also given. 3 refs., 3 figs., 1 tab

Superconducting linac booster for NSC Pelletron

International Nuclear Information System (INIS)

Roy, A.; Prakash, P.N.; Ajithkumar, B.P.; Ghosh, S.; Changrani, T.; Mehta, R.; Sarkar, A.; Muralidhar, S.; Dutt, R.N.; Kumar, M.; Shepard, K.W.; and others.

1996-01-01

The progress made in the heavy ion superconducting linac booster project for the Nuclear Science Centre Pelletron accelerator is overviewed. Prototypes of the accelerating structure have been fabricated at Argonne National Laboratory and undergone several diagnostic tests. In the first phase heavy ions up to mass 80 will be accelerated to energies above the Coulomb barrier and in the second phase the mass limit would be increased to 120. The subsystems of the project are the basic accelerating structures, the RF instrumentation and control, the cryogenic system and the beam optics. Preliminary designs for the buncher and linac cryostats have been made. Several prototypes of RF electronics and control modules have been fabricated and tested. (R.P.)

RF field control for Kaon Factory booster cavities

International Nuclear Information System (INIS)

Craig, S.T.; de Jong, M.S.

1992-08-01

A conceptual design is developed for control of the Kaon Factory booster rf accelerating fields. This design addresses control of cavity: tuning, voltage amplitude, and voltage phase angle. Time-domain simulations were developed to evaluate the proposed controllers. These simulations indicate that adequate tuning performance can be obtained with the combination of adaptive feed forward and proportional feedback control. Voltage amplitude and voltage phase can be adequately controlled using non-adaptive feed forward and proportional feedback control. (Author) (figs., tabs.)

Thermodynamic and chemical parameters of the exhaust effluents from the HARPOON booster motor

Science.gov (United States)

Stephens, J. B.; Goldford, A. I.

1978-01-01

The exhaust products from the Harpoon booster motors were analyzed using both thermodynamic analysis and finite-rate chemistry. The resulting constituents are presented together with a discussion of the techniques employed.

Hydrogen sulfide booster compressors for HWP Manuguru - oil reclamation study - BHEL experience (Paper No. 5.2)

International Nuclear Information System (INIS)

Godbole, A.; Santanam, N.; Murthy, T.S.R.

1992-01-01

BHEL undertook the development of hydrogen sulphide booster compressor with a view to indigenise this most critical equipment in a heavy water plant. Throughout the design, manufacture and shop testing of these booster compressors BHEL had close interaction with Heavy Water Board. This paper describes the problems faced during commissioning of compressors at KCR -Manuguru such as deficiencies in the sizing of LP seal oil drain, development of a process for reclamation of oil and development of alternate sealing arrangement, etc. (author). 1 tab., 4 figs

The superconducting linac booster at the ANU

International Nuclear Information System (INIS)

Weisser, D.C.

1995-02-01

This report outlines the progress of the installation of the superconducting Linac booster at the Australian National University. The Linac is based upon four modules, three of which contain three split-loop resonators. The fourth cryostat was intended to be a superbuncher and so houses only one resonator. The first stage of Linac operation will employ only three modules with 2 MV/m from each resonator. It is expected that the implementation of all nine modules, in subsequent stages, would boost beams by 18 MV/q. The project has fostered productive international collaboration between UK and Australian scientists. 1 tab., 6 figs

Direct Comparison of Immunogenicity Induced by 10- or 13-Valent Pneumococcal Conjugate Vaccine around the 11-Month Booster in Dutch Infants.

Directory of Open Access Journals (Sweden)

Alienke J Wijmenga-Monsuur

Full Text Available Since 2009/10, a 10- and a 13-valent pneumococcal conjugate vaccine (PCV are available, but only the 10-valent vaccine is now being used for the children in the Netherlands. As the vaccines differ in number of serotypes, antigen concentration, and carrier proteins this study was designed to directly compare quantity and quality of the antibody responses induced by PCV10 and PCV13 before and after the 11-month booster.Dutch infants (n = 132 were immunized with either PCV10 or PCV13 and DTaP-IPV-Hib-HepB at the age of 2, 3, 4 and 11 months. Blood samples were collected pre-booster and post-booster at one week and one month post-booster for quantitative and qualitative immunogenicity against 13 pneumococcal serotypes, as well as quantitative immunogenicity against diphtheria, tetanus, pertussis and Haemophilus influenzae type b. We compared immunogenicity induced by PCV13 and PCV10 for their ten shared serotypes.One month post-booster, pneumococcal serotype-specific IgG geometric mean concentrations (GMCs for the PCV13 group were higher compared with the PCV10 group for six serotypes, although avidity was lower. Serotype 19F showed the most distinct difference in IgG and, in contrast to other serotypes, its avidity was higher in the PCV13 group. One week post-booster, opsonophagocytosis for serotype 19F did not differ significantly between the PCV10- and the PCV13 group.Both PCV10 and PCV13 were immunogenic and induced a booster response. Compared to the PCV10 group, the PCV13 group showed higher levels for serotype 19F GMCs and avidity, pre- as well as post-booster, although opsonophagocytosis did not differ significantly between groups. In our study, avidity is not correlated to opsonophagocytotic activity (OPA and correlations between IgG and OPA differ per serotype. Therefore, besides assays to determine IgG GMCs, assays to detect opsonophagocytotic activity, i.e., the actual killing of the pneumococcus, are important for PCV evaluation. How

Space Shuttle solid rocket booster

Science.gov (United States)

Hardy, G. B.

1979-01-01

Details of the design, operation, testing and recovery procedures of the reusable solid rocket boosters (SRB) are given. Using a composite PBAN propellant, they will provide the primary thrust (six million pounds maximum at 20 s after ignition) within a 3 g acceleration constraint, as well as thrust vector control for the Space Shuttle. The drogues were tested to a load of 305,000 pounds, and the main parachutes to 205,000. Insulation in the solid rocket motor (SRM) will be provided by asbestos-silica dioxide filled acrylonitrile butadiene rubber ('asbestos filled NBR') except in high erosion areas (principally in the aft dome), where a carbon-filled ethylene propylene diene monomer-neopreme rubber will be utilized. Furthermore, twenty uses for the SRM nozzle will be allowed by its ablative materials, which are principally carbon cloth and silica cloth phenolics.

CFD Assessment of Forward Booster Separation Motor Ignition Overpressure on ET XT 718 Ice/Frost Ramp

Science.gov (United States)

Tejnil, Edward; Rogers, Stuart E.

2012-01-01

Computational fluid dynamics assessment of the forward booster separation motor ignition over-pressure was performed on the space shuttle external tank X(sub T) 718 ice/frost ramp using the flow solver OVERFLOW. The main objective of this study was the investigation of the over-pressure during solid rocket booster separation and its affect on the local pressure and air-load environments. Delta pressure and plume impingement were investigated as a possible contributing factor to the cause of the debris loss on shuttle missions STS-125 and STS-127. A simplified computational model of the Space Shuttle Launch Vehicle was developed consisting of just the external tank and the solid rocket boosters with separation motor nozzles and plumes. The simplified model was validated by comparison to full fidelity computational model of the Space Shuttle without the separation motors. Quasi steady-state plume solutions were used to calibrate the thrust of the separation motors. Time-accurate simulations of the firing of the booster-separation motors were performed. Parametric studies of the time-step size and the number of sub-iterations were used to find the best converged solution. The computed solutions were compared to previous OVERFLOW steady-state runs of the separation motors with reaction control system jets and to ground test data. The results indicated that delta pressure from the overpressure was small and within design limits, and thus was unlikely to have contributed to the foam losses.

Booster: Development of a Toolbox for Triage of a Large Group of Individuals Exposed to Radioactive Material

International Nuclear Information System (INIS)

Schoepff, V.; Carrel, F.; Gmar, M.; Lemaire, H.; Carvajal, F.; Perez-Llopis, I.; Gaboriau, D.-C.; Morrison, C.-G.; Almasi, I.; Szabo, S.; Kovacs, A; Szeles, E.; Amgarou, K.; Menaa, N.; Morat, L.; Testard, I.; Ugolin, N.; Viau, M.; Becker, F.; Raskob, W.; Trybushnyi, D.; Vincze, A.

2013-06-01

The effective management of an event involving the exposure of a large number of people to radioactive material requires a mechanism for fast triage of exposed people. BOOSTER is a project founded by the European Union under the Seventh Framework Programme, addressing this requirement. It is a capability project designed to provide an integrated system which could easily be deployed and used. For this purpose, the BOOSTER consortium, relying on the expertise of seven members, researches and develops new approaches to allow an effective and fast management of most kind of nuclear threats. BOOSTER System was designed to help first responders mitigating the crisis by providing the necessary information to quickly assess the radiological situation, to support triage staff in performing an efficient and fast categorization of the potentially affected victims, and to give medical staff crucial information for further treatment at medium or long term post-accident. (authors)

Community awareness and predictors of uptake of pertussis booster vaccine in South Australian adults.

Science.gov (United States)

Clarke, Michelle; Thomas, Natalie; Giles, Lynne; Marshall, Helen

2015-12-16

Pertussis is a highly virulent vaccine preventable disease that remains a global challenge. This study aimed to assess community knowledge of pertussis infection as well as awareness and uptake of adult pertussis booster vaccine. A cross-sectional survey was conducted of randomly selected households in South Australia by Computer Assisted Telephone Interviews in 2011. Survey data were weighted to the age, gender and geographical area profile of the population. From 3124 randomly sampled contactable households, 1967 interviews were conducted (participation rate 63%) with individuals aged 18-93 years, including 608 parents of children aged pertussis (whooping cough) and 18% reported that a household member had previously contracted whooping cough infection. Most respondents considered whooping cough to be highly contagious (73%) and severe for infants (89%). Over half (51%) of those surveyed were aware that family members commonly transmit pertussis to infants. Despite high knowledge, pertussis vaccine uptake was low, with only 10% of respondents reporting pertussis vaccination in the previous five years. Whilst 61% of respondents were aware of the availability of an adult pertussis booster vaccine, only 8% (n=154) reported their Family Physician had discussed it with them. If provided free, 77% agreed that they would be more likely to accept a booster pertussis vaccination. Independent predictors of recent pertussis vaccination included higher education, larger household size, perception of greater disease severity for infants and discussion with a Family Physician about pertussis vaccination. Whilst knowledge regarding transmission and severity of Bordetella pertussis was high, uptake of pertussis vaccination for adults is remarkably low amongst the South Australian community. Improved awareness regarding the availability of a booster pertussis vaccine through Family Physicians and/or provision of funded pertussis vaccination for adults has the potential to improve

Yellow Fever Vaccine Booster Doses: Recommendations of the Advisory Committee on Immunization Practices, 2015.

Science.gov (United States)

Staples, J Erin; Bocchini, Joseph A; Rubin, Lorry; Fischer, Marc

2015-06-19

On February 26, 2015, the Advisory Committee on Immunization Practices (ACIP) voted that a single primary dose of yellow fever vaccine provides long-lasting protection and is adequate for most travelers. ACIP also approved recommendations for at-risk laboratory personnel and certain travelers to receive additional doses of yellow fever vaccine (Box). The ACIP Japanese Encephalitis and Yellow Fever Vaccines Workgroup evaluated published and unpublished data on yellow fever vaccine immunogenicity and safety. The evidence for benefits and risks associated with yellow fever vaccine booster doses was evaluated using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) framework. This report summarizes the evidence considered by ACIP and provides the updated recommendations for yellow fever vaccine booster doses.

Niobium quarter-wave cavity for the New Delhi booster linac

International Nuclear Information System (INIS)

Shepard, K.W.; Roy, A.; Potukuchi, P.N.

1997-01-01

This paper reports the completion of development of a 97 Mhz niobium coaxial quarter-wave cavity to be used in a booster linac for the New Delhi 16UD pellatron electrostatic accelerator. A prototype cavity, which incorporates a niobium-bellows tuning device, has been completed and operated at 4.2 K at accelerating gradients above 4 MV/m for extended periods of time

Niobium quarter-wave cavity for the New Delhi booster linac

Energy Technology Data Exchange (ETDEWEB)

Shepard, K.W. [Argonne National Lab., IL (United States); Roy, A.; Potukuchi, P.N. [Nuclear Science Centre, New Delhi (India)

1997-09-01

This paper reports the completion of development of a 97 Mhz niobium coaxial quarter-wave cavity to be used in a booster linac for the New Delhi 16UD pellatron electrostatic accelerator. A prototype cavity, which incorporates a niobium-bellows tuning device, has been completed and operated at 4.2 K at accelerating gradients above 4 MV/m for extended periods of time.

Baseline immunity to diphtheria and immunologic response after booster vaccination with reduced diphtheria and tetanus toxoid vaccine in Thai health care workers.

Science.gov (United States)

Wiboonchutikul, Surasak; Manosuthi, Weerawat; Sangsajja, Chariya; Thientong, Varaporn; Likanonsakul, Sirirat; Srisopha, Somkid; Termvises, Patamavadee; Rujitip, Jitlada; Loiusirirotchanakul, Suda; Puthavathana, Pilaipan

2014-07-01

A prospective study to evaluate immune status against diphtheria and immunologic response after tetanus-diphtheria (Td) booster vaccination was conducted in 250 Thai health care workers (HCWs). A protective antibody was found in 89.2% of the HCWs (95% confidence interval [CI], 83.3%-91.5%) before receipt of the Td booster vaccination, compared with 97.2% (95% CI, 95.1%-99.3%) after receipt of the first dose of booster (P diphtheria increased from 0.39 IU/mL (95% CI, 0.35-0.44 IU/mL) before the Td booster vaccination to 1.20 IU/mL (95% CI, 1.12-1.29 IU/mL) after the vaccination (P diphtheria, which still circulates in Thailand. Copyright © 2014 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Mosby, Inc. All rights reserved.

Construction and early commissioning results of the AGS Booster

International Nuclear Information System (INIS)

Weng, W.T.; Ahrens, L.; Damm, R.; McNerney, A.J.

1991-01-01

The AGS Booster synchrotron has been designed to accelerate protons from 200 MeV to 1.5 GeV and heavy ions from several MeV per nucleon to several hundred MeV per nucleon for all the nuclei up to gold. The design requirements and measurements results of major accelerator components and systems are presented. The early commissioning results of the injection is also presented. 12 refs., 9 figs., 2 tabs

Design of the AGS Booster beam position monitor system

International Nuclear Information System (INIS)

Beadle, E.; Brennan, J.M.; Ciardullo, D.J.; Savino, J.; Stanziani, V.; Thomas, R.; Van Zwienen, W.; Witkover, R.L.; Schulte, E.

1989-01-01

The AGS Booster beam position monitor system must cover a wide range of beam intensity and bunch length for proton and heavy ion acceleration. The detector is designed to maintain 0.1 mm local tolerance following 300 degree C bakeout. The electronics will be located in the tunnel, communicating via fiber optic links to avoid ground loops. The design will be described and test results for prototype units presented. 5 refs., 4 figs

Long-Term Safety and Immunogenicity of a Tetravalent Live-Attenuated Dengue Vaccine and Evaluation of a Booster Dose Administered to Healthy Thai Children.

Science.gov (United States)

Watanaveeradej, Veerachai; Simasathien, Sriluck; Mammen, Mammen P; Nisalak, Ananda; Tournay, Elodie; Kerdpanich, Phirangkul; Samakoses, Rudiwilai; Putnak, Robert J; Gibbons, Robert V; Yoon, In-Kyu; Jarman, Richard G; De La Barrera, Rafael; Moris, Philippe; Eckels, Kenneth H; Thomas, Stephen J; Innis, Bruce L

2016-06-01

We evaluated the safety and immunogenicity of two doses of a live-attenuated, tetravalent dengue virus vaccine (F17/Pre formulation) and a booster dose in a dengue endemic setting in two studies. Seven children (7- to 8-year-olds) were followed for 1 year after dose 2 and then given a booster dose (F17/Pre formulation), and followed for four more years (Child study). In the Infant study, 49 2-year-olds, vaccinated as infants, were followed for approximately 3.5 years after dose 2 and then given a booster dose (F17) and followed for one additional year. Two clinically notable events were observed, both in dengue vaccine recipients in the Infant study: 1 case of dengue approximately 2.7 years after dose 2 and 1 case of suspected dengue after booster vaccinations. The booster vaccinations had a favorable safety profile in terms of reactogenicity and adverse events reported during the 1-month follow-up periods. No vaccine-related serious adverse events were reported during the studies. Neutralizing antibodies against dengue viruses 1-4 waned during the 1-3 years before boosting, which elicited a short-lived booster response but did not provide a long-lived, multivalent antibody response in most subjects. Overall, this candidate vaccine did not elicit a durable humoral immune response. © The American Society of Tropical Medicine and Hygiene.

Update on Risk Reduction Activities for a Liquid Advanced Booster for NASA's Space Launch System

Science.gov (United States)

Crocker, Andrew M.; Doering, Kimberly B; Meadows, Robert G.; Lariviere, Brian W.; Graham, Jerry B.

2015-01-01

The stated goals of NASA's Research Announcement for the Space Launch System (SLS) Advanced Booster Engineering Demonstration and/or Risk Reduction (ABEDRR) are to reduce risks leading to an affordable Advanced Booster that meets the evolved capabilities of SLS; and enable competition by mitigating targeted Advanced Booster risks to enhance SLS affordability. Dynetics, Inc. and Aerojet Rocketdyne (AR) formed a team to offer a wide-ranging set of risk reduction activities and full-scale, system-level demonstrations that support NASA's ABEDRR goals. For NASA's SLS ABEDRR procurement, Dynetics and AR formed a team to offer a series of full-scale risk mitigation hardware demonstrations for an affordable booster approach that meets the evolved capabilities of the SLS. To establish a basis for the risk reduction activities, the Dynetics Team developed a booster design that takes advantage of the flight-proven Apollo-Saturn F-1. Using NASA's vehicle assumptions for the SLS Block 2, a two-engine, F-1-based booster design delivers 150 mT (331 klbm) payload to LEO, 20 mT (44 klbm) above NASA's requirements. This enables a low-cost, robust approach to structural design. During the ABEDRR effort, the Dynetics Team has modified proven Apollo-Saturn components and subsystems to improve affordability and reliability (e.g., reduce parts counts, touch labor, or use lower cost manufacturing processes and materials). The team has built hardware to validate production costs and completed tests to demonstrate it can meet performance requirements. State-of-the-art manufacturing and processing techniques have been applied to the heritage F-1, resulting in a low recurring cost engine while retaining the benefits of Apollo-era experience. NASA test facilities have been used to perform low-cost risk-reduction engine testing. In early 2014, NASA and the Dynetics Team agreed to move additional large liquid oxygen/kerosene engine work under Dynetics' ABEDRR contract. Also led by AR, the

The Effects of Space-Charge on the Dynamics of the Ion Booster in the Jefferson Lab EIC (JLEIC)

Energy Technology Data Exchange (ETDEWEB)

Bogacz, Alex [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Nissen, Edward [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States)

2017-05-01

Optimization of the booster synchrotron design to operate in the extreme space-charge dominated regime is proposed. This study is motivated by the ultra-high luminosity promised by the JLEIC accelerator complex, which poses several beam dynamics and lattice design challenges for its individual components. We examine the effects of space charge on the dynamics of the booster synchrotron for the proposed JLEIC electron ion collider. This booster will inject and accumulate protons and heavy ions at an energy of 280 MeV and then engage in a process of acceleration and electron cooling to bring it to its extraction energy of 8 GeV. This would then be sent into the ion collider ring part of JLEIC. In order to examine the effects of space charge on the dynamics of this process we use the software SYNERGIA.

Antibody response to booster vaccination with tetanus and diphtheria in adults exposed to perfluorinated alkylates.

Science.gov (United States)

Kielsen, Katrine; Shamim, Zaiba; Ryder, Lars P; Nielsen, Flemming; Grandjean, Philippe; Budtz-Jørgensen, Esben; Heilmann, Carsten

2016-01-01

Recent studies suggest that exposure to perfluorinated alkylate substances (PFASs) may induce immunosuppression in humans and animal models. In this exploratory study, 12 healthy adult volunteers were recruited. With each subject, serum-PFAS concentrations were measured and their antibody responses prospectively followed for 30 days after a booster vaccination with diphtheria and tetanus. The results indicated that serum-PFAS concentrations were positively correlated and positively associated with age and male sex. The specific antibody concentrations in serum were increased from Day 4 to Day 10 post-booster, after which a constant concentration was reached. Serum PFAS concentrations showed significant negative associations with the rate of increase in the antibody responses. Interestingly, this effect was particularly strong for the longer-chain PFASs. All significant associations remained significant after adjustment for sex and age. Although the study involved a small number of subjects, these findings of a PFAS-associated reduction of the early humoral immune response to booster vaccination in healthy adults supported previous findings of PFAS immunosuppression in larger cohorts. Furthermore, the results suggested that cellular mechanisms right after antigen exposure should be investigated more closely to identify possible mechanisms of immunosuppression from PFAS.

Boosters and barriers for direct cardiac reprogramming.

Science.gov (United States)

Talkhabi, Mahmood; Zonooz, Elmira Rezaei; Baharvand, Hossein

2017-06-01

Heart disease is currently the most significant cause of morbidity and mortality worldwide, which accounts for approximately 33% of all deaths. Recently, a promising and alchemy-like strategy has been developed called direct cardiac reprogramming, which directly converts somatic cells such as fibroblasts to cardiac lineage cells such as cardiomyocytes (CMs), termed induced CMs or iCMs. The first in vitro cardiac reprogramming study, mediated by cardiac transcription factors (TFs)-Gata4, Tbx5 and Mef2C-, was not enough efficient to produce an adequate number of fully reprogrammed, functional iCMs. As a result, numerous combinations of cardiac TFs exist for direct cardiac reprogramming of mouse and human fibroblasts. However, the efficiency of direct cardiac reprogramming remains low. Recently, a number of cellular and molecular mechanisms have been identified to increase the efficiency of direct cardiac reprogramming and the quality of iCMs. For example, microgrooved substrate, cardiogenic growth factors [VEGF, FGF, BMP4 and Activin A], and an appropriate stoichiometry of TFs boost the direct cardiac reprogramming. On the other hand, serum, TGFβ signaling, activators of epithelial to mesenchymal transition, and some epigenetic factors (Bmi1 and Ezh2) are barriers for direct cardiac reprogramming. Manipulating these mechanisms by the application of boosters and removing barriers can increase the efficiency of direct cardiac reprogramming and possibly make iCMs reliable for cell-based therapy or other potential applications. In this review, we summarize the latest trends in cardiac TF- or miRNA-based direct cardiac reprogramming and comprehensively discuses all molecular and cellular boosters and barriers affecting direct cardiac reprogramming. Copyright © 2017 Elsevier Inc. All rights reserved.

Investigation of Post-Flight Solid Rocket Booster Thermal Protection System

Science.gov (United States)

Nelson, Linda A.

2006-01-01

After every Shuttle mission, the Solid Rocket Boosters (SRBs) are recovered and observed for missing material. Most of the SRB is covered with a cork-based thermal protection material (MCC-l). After the most recent shuttle mission, STS-114, the forward section of the booster appeared to have been impacted during flight. The darkened fracture surfaces indicated that this might have occurred early in flight. The scope of the analysis included microscopic observations to assess the degree of heat effects and locate evidence of the impact source as well as chemical analysis of the fracture surfaces and recovered foreign material using Fourier Transform Infrared Spectroscopy and Scanning Electron Microscopy/Energy Dispersive Spectroscopy. The amount of heat effects and presence of soot products on the fracture surface indicated that the material was impacted prior to SRB re-entry into the atmosphere. Fragments of graphite fibers found on these fracture surfaces were traced to slag inside the Solid Rocket Motor (SRM) that forms during flight as the propellant is spent and is ejected throughout the descent of the SRB after separation. The direction of the impact mark matches with the likely trajectory of SRBs tumbling prior to re-entry.

Progress on the IPNS Enriched Uranium Booster Target

International Nuclear Information System (INIS)

Knox, A.E.; Carpenter, J.M.; Bailey, J.L.

1986-09-01

We describe the Enriched Uranium Booster Target designed for use in Argonne's Intense Pulsed Neutron Source. This report contains a general description of the system, and descriptions of the thermal-hydraulic and loss-of-coolant accident analyses, of the neutronic, criticality and power density calculations, of the assessment of radiation and thermal cycling growth, and of the disk fabrication methods. We also describe the calculations of radionuclide buildup and the related hazards analysis and our calculations of the temperature and stress profiles in the disks, and briefly allude to considerations of security and safeguards

Analytical and experimental analysis of YALINA-Booster and YALINA-Thermal assemblies

International Nuclear Information System (INIS)

Kiyavitskaya, H.; Bournos, V.; Mazanik, S.; Khilmanovich, A.; Martsinkevich, B.; Routkovskaya, Ch.; Edchik, I.; Fokov, Y.; Sadovich, S.; Fedorenko, A.; Gohar, Y.; Talamo, A.

2010-01-01

Full text: Accelerator Driven Systems (ADS) may play an important role in future nuclear fuel cycles to reduce the longterm radiotoxicity and volume of spent nuclear fuel. It is proposed that ADS will produce energy and incinerate radioactive waste. This technology was called Accelerator Driven Transmutation Technology (ADTT). The most important problems of this technology are monitoring of a reactivity level in on-line regime, a choice of neutron spectrum appropriate for incineration of Minor Actinides (MA) and transmutation of Long Lived Fission Products (LLFP) and etc. Before the designing and construction of an installation it is necessary to carry out R and D to validate codes, nuclear data libraries and other instrumentations. The YALINA facility is designed to study the ADS physics and to investigate the transmutation reaction rates of MA and LLFP. The main objective of the YALINA benchmark is to compare the results from different calculation methods with each other and experimental data. The benchmark is based on the current YALINA facility configuration, which provides the opportunity to verify the prediction capability of the different methods. The experimental data have been obtained in the frame of the ISTC Projects B1341 'Analytical and experimental evaluation of the possibility to create a universal volume source of neutrons in the sub-critical booster assembly with low enrichment uranium fuel driven by a neutron generator' and B1732P 'Analytical and experimental evaluating the possibility of creation of universal volume source of neutrons in the sub-critical booster assembly with low enriched uranium fuel driven by the neutron generator'. In this paper a comparison of the experimental and calculated data obtained for YALINA-Booster subcritical assembly with a fuel of different enrichment and for YALINA-Thermal with a different number of control rods (216, 245 and 280) will be done.

Run 16 Tandem gold performance in the injectors and possible improvement with AGS type 6:3:1 bunch merge in the Booster

Energy Technology Data Exchange (ETDEWEB)

Zeno, Keith [Brookhaven National Lab. (BNL), Upton, NY (United States)

2016-10-21

During Run 16 the Tandem was used as the Gold pre-injector for a brief time so that RHIC could continue running while EBIS was down for repairs. Given the time constraints, the setup was largely derived from the EBIS Au setup. The EBIS Au setup used a 4:2:1 bunch merge in the Booster and a 12:6:2 bunch merge in the AGS.1 This note will describe the Tandem Au setup and compare it to that used for EBIS Au. The bunch merge in the Booster for Tandem Au did not work well, and it seems likely that the performance would’ve been significantly better if it did. An AGS type 6:3:1 merge in the Booster is described which might improve matters.2 Somewhat speculative estimates for the AGS bunch intensity and emittance, if that merge were successful in reducing the Booster extraction emittance to EBIS Au levels, are also given for several potential setups. Using 6 Booster loads from the Tandem, the AGS bunch intensity at extraction reached about 2.5e9 ions with a longitudinal emittance (ε) of about 0.59 eV·s/n.3 Using 12 Booster loads from EBIS, the peak bunch intensity and ε was about 3.1e9 ions and 0.75 eV·s/n, respectively. A 6.4 sec supercycle was used for both at the time, but the Tandem Au supercycle (barring any potential issues with Tandem) could probably have been reduced to about 4.6 sec.

Progress on the Design of a Perpendicularly Biased 2nd Harmonic Cavity for the Fermilab Booster

Energy Technology Data Exchange (ETDEWEB)

Madrak, R. L. [Fermilab; Dey, J. E. [Fermilab; Duel, K. L. [Fermilab; Kuharik, J. C. [Fermilab; Pellico, W. A. [Fermilab; Reid, J. S. [Fermilab; Romanov, G. [Fermilab; Slabough, M. [Fermilab; Sun, D. [Fermilab; Tan, C. Y. [Fermilab; Terechkine, I. [Fermilab

2016-10-01

perpendicularly biased 2nd harmonic cavity is being designed and built for the Fermilab Booster. Its purpose is to flatten the bucket at injection and thus change the longitudinal beam distribution to decrease space charge effects. It can also help at extraction. The cavity frequency range is 76 – 106 MHz. The power amplifier will be built using the Y567B tetrode, which is also used for the fundamental mode cavities in the Fermilab Booster. We discuss recent progress on the cavity, the biasing solenoid design and plans for testing the tuner's garnet material

The linac and booster RF systems for a dedicated injector for SPEAR

International Nuclear Information System (INIS)

Weaver, J.N.; Baird, S.; Baltay, M.; Borland, M.; Nuhn, H.D.; Safranek, J.; Chavis, C.; Emery, L.; Genin, R.D.; Hettel, R.; Morales, H.; Sebek, J.; Voss, J.; Wang, D.; Wiedemann, H.; Youngmann, B.; Miller, R.H.

1991-01-01

A 120 MeV, 2,856 MHz, TW linac, with a microwave gun, alpha magnet, and chopper, has been built at SSRL as a preinjector for and along with a 3 GeV booster synchrotron ring. The resulting injector will be available on demand to fill SPEAR, which is a storage ring now dedicated to synchrotron light production. The linac sections were purchased from China, the XK-5 klystrons were obtained surplus from SLAC, the modulators are a variation on those at SLAC and were built by SSRL, the alpha magnet and chopper were designed and built at SSRL and the microwave gun was designed and built in collaboration with Varian Associates. The RF system for the booster ring is similar to those at SPEAR and PEP and was built by SSRL. Some of the interesting mechanical and electrical details are discussed and the operating characteristics of the linac and ring RF system are highlighted

The linac and booster RF systems for a dedicated injector for SPEAR

International Nuclear Information System (INIS)

Weaver, J.N.; Baird, S.; Baltay, M.; Borland, M.; Nuhn, H.D.; Safranek, J.; Chavis, C.; Emery, L.; Genin, R.D.; Hettel, R.; Morales, H.; Sebek, J.; Voss, J.; Wang, H.; Wiedemann, H.; Youngmann, B.

1991-05-01

A 120 MeV, 2856 MHz, TW linac, with a microwave gun, alpha magnet, and chopper, has been built at SSRL as a preinjector for and along with a 3 GeV booster synchrotron ring. The resulting injector will be available on demand to fill SPEAR, which is a storage ring now dedicated to synchrotron light production. The linac sections were purchased from China, the XK-5 klystrons were obtained surplus from SLAC, the modulators are a variation on those at SLAC and were built by SSRL, the alpha magnet and chopper were designed and built at SSRL and the microwave gun was designed and built in collaboration with Varian Associates. The rf system for the booster ring is similar to those at SPEAR and PEP and was built by SSRL. Some of the interesting mechanical and electrical details are discussed and the operating characteristics of the linac and ring rf system are highlighted. 8 refs., 6 figs

Monte Carlo modeling and analyses of YALINA-booster subcritical assembly part 1: analytical models and main neutronics parameters

International Nuclear Information System (INIS)

Talamo, A.; Gohar, M. Y. A.; Nuclear Engineering Division

2008-01-01

This study was carried out to model and analyze the YALINA-Booster facility, of the Joint Institute for Power and Nuclear Research of Belarus, with the long term objective of advancing the utilization of accelerator driven systems for the incineration of nuclear waste. The YALINA-Booster facility is a subcritical assembly, driven by an external neutron source, which has been constructed to study the neutron physics and to develop and refine methodologies to control the operation of accelerator driven systems. The external neutron source consists of Californium-252 spontaneous fission neutrons, 2.45 MeV neutrons from Deuterium-Deuterium reactions, or 14.1 MeV neutrons from Deuterium-Tritium reactions. In the latter two cases a deuteron beam is used to generate the neutrons. This study is a part of the collaborative activity between Argonne National Laboratory (ANL) of USA and the Joint Institute for Power and Nuclear Research of Belarus. In addition, the International Atomic Energy Agency (IAEA) has a coordinated research project benchmarking and comparing the results of different numerical codes with the experimental data available from the YALINA-Booster facility and ANL has a leading role coordinating the IAEA activity. The YALINA-Booster facility has been modeled according to the benchmark specifications defined for the IAEA activity without any geometrical homogenization using the Monte Carlo codes MONK and MCNP/MCNPX/MCB. The MONK model perfectly matches the MCNP one. The computational analyses have been extended through the MCB code, which is an extension of the MCNP code with burnup capability because of its additional feature for analyzing source driven multiplying assemblies. The main neutronics parameters of the YALINA-Booster facility were calculated using these computer codes with different nuclear data libraries based on ENDF/B-VI-0, -6, JEF-2.2, and JEF-3.1

Monte Carlo modeling and analyses of YALINA-booster subcritical assembly part 1: analytical models and main neutronics parameters.

Energy Technology Data Exchange (ETDEWEB)

Talamo, A.; Gohar, M. Y. A.; Nuclear Engineering Division

2008-09-11

This study was carried out to model and analyze the YALINA-Booster facility, of the Joint Institute for Power and Nuclear Research of Belarus, with the long term objective of advancing the utilization of accelerator driven systems for the incineration of nuclear waste. The YALINA-Booster facility is a subcritical assembly, driven by an external neutron source, which has been constructed to study the neutron physics and to develop and refine methodologies to control the operation of accelerator driven systems. The external neutron source consists of Californium-252 spontaneous fission neutrons, 2.45 MeV neutrons from Deuterium-Deuterium reactions, or 14.1 MeV neutrons from Deuterium-Tritium reactions. In the latter two cases a deuteron beam is used to generate the neutrons. This study is a part of the collaborative activity between Argonne National Laboratory (ANL) of USA and the Joint Institute for Power and Nuclear Research of Belarus. In addition, the International Atomic Energy Agency (IAEA) has a coordinated research project benchmarking and comparing the results of different numerical codes with the experimental data available from the YALINA-Booster facility and ANL has a leading role coordinating the IAEA activity. The YALINA-Booster facility has been modeled according to the benchmark specifications defined for the IAEA activity without any geometrical homogenization using the Monte Carlo codes MONK and MCNP/MCNPX/MCB. The MONK model perfectly matches the MCNP one. The computational analyses have been extended through the MCB code, which is an extension of the MCNP code with burnup capability because of its additional feature for analyzing source driven multiplying assemblies. The main neutronics parameters of the YALINA-Booster facility were calculated using these computer codes with different nuclear data libraries based on ENDF/B-VI-0, -6, JEF-2.2, and JEF-3.1.

Limits on the transverse phase space density in the Fermilab Booster

International Nuclear Information System (INIS)

Ankenbrandt, C.; Holmes, S.D.

1987-09-01

Recent results on intensity and transverse density limitations in the Fermilab 8-GeV Booster are presented. The evidence suggests that the limits are set by incoherent space-charge effects at low energy. Data are interpreted in terms of the space-charge tune shift and possible means of improving performance further are discussed. 8 refs., 3 figs

SSC High Energy Booster resonance corrector and dynamic tune scanning simulation

Energy Technology Data Exchange (ETDEWEB)

Zhang, P.; Machida, S.

1993-05-01

A resonance correction system for the High Energy Booster (HEB) of the Superconducting Super Collider (SSCL) was investigated by means of dynamic multiparticle tracking. In the simulation the operating tune is scanned as a function of time so that the bunch goes through a resonance. The performance of the half integer and third integer resonance correction system is demonstrated.

Terpineol as a novel octane booster for extending the knock limit of gasoline

KAUST Repository

Vallinayagam, R.; Vedharaj, S.; Naser, Nimal; Roberts, William L.; Dibble, Robert W.; Sarathy, Mani

2016-01-01

Improving the octane number of gasoline offers the potential of improved engine combustion, as it permits spark timing advancement without engine knock. This study proposes the use of terpineol as an octane booster for gasoline in a spark ignited

Simulation of turn-by-turn passage of protons through the H-minus stripping foil in booster

Energy Technology Data Exchange (ETDEWEB)

Gardner, C. [Brookhaven National Lab. (BNL), Upton, NY (United States)

2017-07-06

Equations for transverse emittance growth due to multiple passes of circulating proton beam through the H-minus stripping foil in Booster were developed in [1]. These were based on simple principles of statistics and simple assumptions about the initial distribution of particles incident on the foil. It was assumed there that the foil dimensions and position of the incoming beam are such that all particles hit the foil on every turn around the machine. In the present note we assume only that all incoming H-minus ions from Linac hit the foil and are stripped of their electrons. The resulting protons circulate indefinitely around the machine. Setups in which the foil width is reduced so that not all protons hit the foil on every turn are studied here by simulation. The aim is to determine the effectiveness of such setups in reducing the emittance growth of circulating proton beam during the injection of H-minus beam. The simulations also serve as a check of the equations developed in [1], and vice versa. The particulars of the simulation setup are given in Sections 1 through 11. Figures 1 through 12 show simulation results for the case in which all particles hit the foil on every turn. The results are in good agreement with those obtained from the equations of reference [1]. Figures 13 through 19 show simulation results for various setups in which the foil width is reduced. These results are summarized in Section 12. In all gures the horizontal axis gives the turn number. The unit of the vertical axis is micrometers ( m) in all plots of emittance.

The safety and reactogenicity of a reduced-antigen-content diphtheria-tetanus-acellular pertussis (dTpa) booster vaccine in healthy Vietnamese children.

Science.gov (United States)

Anh, Dang Duc; Jayadeva, Girish; Kuriyakose, Sherine; Han, Htay Htay

2016-08-17

Despite effective infant immunization against pertussis, the disease continues to circulate due to waning immunity. Booster vaccinations against pertussis beyond infancy are widely recommended. In Vietnam, however, no recommendations for pertussis boosters beyond the second year of life exist. This open-label, single-centre study was designed to assess the safety of a single booster dose of reduced-antigen-content-diphtheria-tetanus-acellular-pertussis vaccine (dTpa) in 300 healthy Vietnamese children (mean age 7.9years), who had completed primary vaccination against diphtheria, tetanus and pertussis. Solicited symptoms were recorded for 4days and unsolicited and serious adverse events (SAEs) for 31days post-vaccination. Pain and fatigue were the most common solicited local and general symptoms in 35.0% and 14.0% of children, respectively. Grade 3 swelling occurred in 3 children; no large injection site reactions or SAEs were reported. The dTpa booster vaccine was well tolerated and this study supports its administration in school age Vietnamese children. Copyright © 2016 GSK group of companies. Published by Elsevier Ltd.. All rights reserved.

Rf beam control for the AGS Booster

International Nuclear Information System (INIS)

Brennan, J.M.

1994-01-01

RF beam control systems for hadron synchrotrons have evolved over the past three decades into an essentially standard design. The key difference between hadron and lepton machines is the absence of radiation damping and existence of significant frequency variation in the case of hadrons. Although the motion of the hadron in the potential well of the rf wave is inherently stable it is not strongly damped. Damping must be provided by electronic feedback through the accelerating system. This feedback is typically called the phase loop. The technology of the rf beam control system for the AGS Booster synchrotron is described. First, the overall philosophy of the design is explained in terms of a conventional servo system that regulates the beam horizontal position in the vacuum chamber. The concept of beam transfer functions is fundamental to the mathematics of the design process and is reviewed. The beam transfer functions required for this design are derived from first principles. An overview of the beam signal pick-ups and high level rf equipment is given. The major subsystems, the frequency program, the heterodyne system, and beam feedback loops, are described in detail. Beyond accelerating the beam, the rf system must also synchronize the bunches in the Booster to the buckets in the AGS before transfer. The technical challenge in this process is heightened by the need to accomplish synchronization while the frequency is still changing. Details of the synchronization system are given. This report is intended to serve two purposes. One is to document the hardware and performance of the systems that have been built. The other is to serve as a tutorial vehicle from which the non-expert can not only learn the details of this system but also learn the principles of beam control that have led to the particular design choices made

Rf beam control for the AGS Booster

Energy Technology Data Exchange (ETDEWEB)

Brennan, J.M.

1994-09-26

RF beam control systems for hadron synchrotrons have evolved over the past three decades into an essentially standard design. The key difference between hadron and lepton machines is the absence of radiation damping and existence of significant frequency variation in the case of hadrons. Although the motion of the hadron in the potential well of the rf wave is inherently stable it is not strongly damped. Damping must be provided by electronic feedback through the accelerating system. This feedback is typically called the phase loop. The technology of the rf beam control system for the AGS Booster synchrotron is described. First, the overall philosophy of the design is explained in terms of a conventional servo system that regulates the beam horizontal position in the vacuum chamber. The concept of beam transfer functions is fundamental to the mathematics of the design process and is reviewed. The beam transfer functions required for this design are derived from first principles. An overview of the beam signal pick-ups and high level rf equipment is given. The major subsystems, the frequency program, the heterodyne system, and beam feedback loops, are described in detail. Beyond accelerating the beam, the rf system must also synchronize the bunches in the Booster to the buckets in the AGS before transfer. The technical challenge in this process is heightened by the need to accomplish synchronization while the frequency is still changing. Details of the synchronization system are given. This report is intended to serve two purposes. One is to document the hardware and performance of the systems that have been built. The other is to serve as a tutorial vehicle from which the non-expert can not only learn the details of this system but also learn the principles of beam control that have led to the particular design choices made.

Immunogenicity and safety after booster vaccination of diphtheria, tetanus, and acellular pertussis in young adults: an open randomized controlled trial in Japan.

Science.gov (United States)

Hara, Megumi; Okada, Kenji; Yamaguchi, Yuko; Uno, Shingo; Otsuka, Yasuko; Shimanoe, Chisato; Nanri, Hinako; Horita, Mikako; Ozaki, Iwata; Nishida, Yuichiro; Tanaka, Keitaro

2013-12-01

The recent increase of pertussis in young adults in Japan is hypothesized to be due in part to waning protection from the acellular pertussis vaccine. While a booster immunization may prevent an epidemic of pertussis among these young adults, little is known about the safety and immunogenicity of such a booster with the diphtheria, tetanus, and acellular pertussis vaccine (DTaP), which is currently available in Japan. One hundred and eleven medical students with a mean age of 19.4 years were randomly divided into 2 groups of 55 and 56 subjects and received, respectively, 0.2 or 0.5 ml of DTaP. Immunogenicity was assessed by performing the immunoassay using serum, and the geometric mean concentration (GMC), GMC ratio (GMCR), seropositive rate, and booster response rate were calculated. Adverse reactions and adverse events were monitored for 7 days after vaccination. After booster vaccination in the two groups, significant increases were found in the antibodies against pertussis toxin, filamentous hemagglutinin, diphtheria toxoid, and tetanus toxoid, and the booster response rates for all subjects reached 100%. The GMCs and GMCRs against all antigens were significantly higher in the 0.5-ml group than in the 0.2-ml group. No serious adverse events were observed. Frequencies of local reactions were similar in the 2 groups, although the frequency of severe local swelling was significantly higher in the 0.5-ml group. These data support the acceptability of booster immunization using both 0.2 and 0.5 ml of DTaP for young adults for controlling pertussis. (This study was registered at UMIN-CTR under registration number UMIN000010672.).

Cold chain and virus-free chloroplast-made booster vaccine to confer immunity against different poliovirus serotypes.

Science.gov (United States)

Chan, Hui-Ting; Xiao, Yuhong; Weldon, William C; Oberste, Steven M; Chumakov, Konstantin; Daniell, Henry

2016-11-01

The WHO recommends complete withdrawal of oral polio vaccine (OPV) type 2 by April 2016 globally and replacing with at least one dose of inactivated poliovirus vaccine (IPV). However, high-cost, limited supply of IPV, persistent circulating vaccine-derived polioviruses transmission and need for subsequent boosters remain unresolved. To meet this critical need, a novel strategy of a low-cost cold chain-free plant-made viral protein 1 (VP1) subunit oral booster vaccine after single IPV dose is reported. Codon optimization of the VP1 gene enhanced expression by 50-fold in chloroplasts. Oral boosting of VP1 expressed in plant cells with plant-derived adjuvants after single priming with IPV significantly increased VP1-IgG1 and VP1-IgA titres when compared to lower IgG1 or negligible IgA titres with IPV injections. IgA plays a pivotal role in polio eradication because of its transmission through contaminated water or sewer systems. Neutralizing antibody titres (~3.17-10.17 log 2 titre) and seropositivity (70-90%) against all three poliovirus Sabin serotypes were observed with two doses of IPV and plant-cell oral boosters but single dose of IPV resulted in poor neutralization. Lyophilized plant cells expressing VP1 stored at ambient temperature maintained efficacy and preserved antigen folding/assembly indefinitely, thereby eliminating cold chain currently required for all vaccines. Replacement of OPV with this booster vaccine and the next steps in clinical translation of FDA-approved antigens and adjuvants are discussed. © 2016 The Authors. Plant Biotechnology Journal published by Society for Experimental Biology and The Association of Applied Biologists and John Wiley & Sons Ltd.

An object-oriented implementation of the TRIUMF 92 MHz booster cavity control system

International Nuclear Information System (INIS)

Wilkinson, N.A.; Ludgate, G.A.

1992-01-01

A 92 MHz auxiliary accelerating cavity has been designed for installation inside the TRIUMF cyclotron, operating up to a maximum peak voltage of 200 kV. The cavity doubles the energy gain per turn for accelerating hydrogen ions in the energy region of 400-500 MeV, and reduces by 50% the stripping loss of the ion beam. The control system for the booster comprises a PC-based processor in a VME crate, for local control, and a 68030 processor with an ethernet connection as the interface to the TRIUMF Central Control System. The requirements for the booster control system were established by an object-oriented requirements analysis. Afterward, an object-oriented architectural design step was used to produce the processor allocation of the design, which was then implemented using C, for the VME processor, and a commercial database and screen generator product, for the VAX user interface. (author)

Septa and Distributor Developments for H- Injection into the Booster from LINAC4

CERN Document Server

Borburgh, J; Fowler, T; Hourican, M; Weterings, W

2008-01-01

The construction of Linac4 requires the modification of the existing injection system of the CERN PS Booster. A new transfer line will transport 160 MeV H- ions to this machine. A system of 5 pulsed magnets (BIDIS) and 3 vertical septa (BISMV) will distribute and inject the Linac pulses into the four-vertically separated Booster rings. Subsequently the beam will be injected horizontally, using a local bump created with bumpers (BS magnets) to bring the injected H- beam together with the orbiting proton beam onto the stripper foil. To accommodate the injected H- beam, the first of the BS magnets will have to be a septum-like device, deflecting only the orbiting beam. This paper highlights the requirements and technical issues and describes the solutions to be adopted for both the BIDIS and BISMV. The results of initial prototype testing of the BIDIS magnet will also be presented.

A tool for model based diagnostics of the AGS Booster

International Nuclear Information System (INIS)

Luccio, A.

1993-01-01

A model-based algorithmic tool was developed to search for lattice errors by a systematic analysis of orbit data in the AGS Booster synchrotron. The algorithm employs transfer matrices calculated with MAD between points in the ring. Iterative model fitting of the data allows one to find and eventually correct magnet displacements and angles or field errors. The tool, implemented on a HP-Apollo workstation system, has proved very general and of immediate physical interpretation

Antibody response to booster vaccination with tetanus and diphtheria in adults exposed to perfluorinated alkylates

DEFF Research Database (Denmark)

Kielsen, Katrine; Shamim, Zaiba; Ryder, Lars P.

2016-01-01

Recent studies suggest that exposure to perfluorinated alkylate substances (PFASs) may induce immunosuppression in humans and animal models. In this exploratory study, 12 healthy adult volunteers were recruited. With each subject, serum-PFAS concentrations were measured and their antibody responses...... prospectively followed for 30 days after a booster vaccination with diphtheria and tetanus. The results indicated that serum-PFAS concentrations were positively correlated and positively associated with age and male sex. The specific antibody concentrations in serum were increased from Day 4 to Day 10 post......-booster, after which a constant concentration was reached. Serum PFAS concentrations showed significant negative associations with the rate of increase in the antibody responses. Interestingly, this effect was particularly strong for the longer-chain PFASs. All significant associations remained significant after...

Automatic delamination defect detection in radiographic sequence of rocket boosters

International Nuclear Information System (INIS)

Rebuffel, V.; Pires, S.; Caplier, A.; Lamarque, P.

2003-01-01

Solid rocket motors are routinely examined in real-time X-ray radioscopic mode. The large and cylindrical boosters are rotating between a high energy source and a two dimensional detector. The purpose of this control is to detect possible defects all through the sample. In the tangential configuration, the part of the object that intersects the X-rays beam is the peripheral one, allowing to detect the delamination defect between the propellant and the external metal envelope. But the defect detectability is very poor due to the strong attenuation of the X-rays through the motors. During the rotation of the booster, the system acquires a sequence of radiographs where the defects are visible over several successive instants. We have previously developed a real-time tomo-synthesis system, processing the radiographs on line, and based on a tomo-synthesis reconstruction algorithm in order to improve the signal-to-noise ratio. This system is installed at the industrial site of Kourou, and is currently used by the operators in charge of the visual inspection of the boosters. In this paper, we present a method that processes the digital images obtained by the system in the purpose of automatically extracting the delamination defects. Due to the size and the poor contrast of the defects, a single image is not sufficient to perform this detection. A spatio-temporal aspect is required for the algorithm to be robust and efficient. In a first step, the proposed method computes the apparent local displacement between the current radiograph and a reference one. This reference image is acquired at the beginning of the rotation, with few noise, and is supposed to be defect free. The apparent displacement is due to the non-perfect rotation positioning. It may be uniform or not, depending on the deformation of the insulation liner of the metallic wall. The images are then registered and compared. On the resulting difference image we apply a smoothed threshold to obtain an

User control of the proton beam injection trajectories into the AGS Booster

International Nuclear Information System (INIS)

D'Ottavio, T.; Kponou, A.; Luccio, A.; Alessi, J.G.; Reece, R.K.; Skelly, J.

1991-01-01

The 1.5 GeV (proton) Booster Synchrotron nearing completion at the AGS will get its 200 MeV beam from the linac, via a 34.9 m long linac-to-Booster transport line, LTB. LTB branches off from the existing linac-to-AGS transport line, HEBT, approximately 18.4 m downstream from the linac. A schematic layout of LTB is shown in the bottom part of Fig. 1. The four dipoles, DH2 through DH5, which are identical and are operated in series, provide a 126 degrees bend in the line. We have employed three strategies for implementing control of the trajectory, namely: (1) a global correction (2) a local correction (3) a zeroing correction. These, as well as their implementation, will be discussed. Operating experience obtained from early commissioning runs will be given. The hardware used to implement the correction schemes are the beam position monitors, BPMxxx, orbit correctors, DHxxx and DVxxx, and multiwire profile monitors, MWxxx. The quads are QHxxx and QVxxx. 3 refs., 3 figs

Clinical and economic assessment of different general population strategies of pertussis vaccine booster regarding number of doses and age of application for reducing whooping cough disease burden: a systematic review.

Science.gov (United States)

Rodríguez-Cobo, Iria; Chen, Yen-Fu; Olowokure, Babatunde; Litchfield, Ian

2008-12-09

Pertussis continues to be an important cause of morbidity and mortality in children too young to be fully protected despite high vaccination coverage. This has been attributed to waning immunity in older people, leading to the development of strategies to increase levels of immunity. A systematic review was conducted to assess the clinical and cost effectiveness of four population-based strategies for pertussis booster vaccination: single booster at 12-24 months old, single pre-school booster, single adolescent booster and multiple boosters in adulthood every 10 years. Electronic databases and Internet resources were searched to June 2006. Nine observational studies, four mathematical models and eight economic evaluations were included, evaluating four different strategies. Strong evidence to recommend any of these strategies was not found.

Overview and analysis of the 2016 Gold Run in the Booster and AGS

Energy Technology Data Exchange (ETDEWEB)

Zeno, K. [Brookhaven National Laboratory (BNL), Upton, NY (United States). Alternating Gradient Synchrotron

2016-09-16

Run 16 differed from preceding Au runs in that during most of it a 12:6:2 merge was employed in the AGS instead of an 8:4:2 merge. This was done to provide higher bunch intensities for RHIC. Since the approach to providing higher bunch intensities is, and has been, to merge more Booster bunches of the same intensity into one final bunch, detailing the longitudinal aspects of this setup seems quite relevant. So, aside from providing an overview of the Au portion of Run 16, this note also contains a series of emittance measurements in the Booster and AGS. Comparisons of these to similar measurements in previous runs are also made in hopes of gaining a better understanding of what factors contribute to the emittance of a bunch at AGS extraction. The note also tries to provide some context in which to understand the various merge schemes and describes a potential 8 to 1 type merge.

PS BOOSTER BEAM TESTS OF THE NEW DIGITAL BEAM CONTROL SYSTEM FOR LEIR

CERN Document Server

Angoletta, Maria Elena; Bento, J; De Long, J H; Findlay, A; Matuszkiewicz, P; Pedersen, F; Salom-Sarasqueta, A; CERN. Geneva. AB Department

2005-01-01

We have been developing a scaled-down prototype of the new digital beam control and cavity servoing system for CERN’s Low Energy Ion Ring (LEIR) slated for commissioning in 2005. The system’s hardware and software, developed as part of a CERN-BNL collaboration, are based on new all-digital technology already deployed at BNL's AGS Booster. The system relies on VME modules, carrying Digital Signal Processors (DSPs) as well as Field Programmable Gate Arrays (FPGAs), and daughter cards. New concepts deployed include software implementation, through DSPs & FPGAs, of functions traditionally executed by analogue hardware, such as reference-functions and timings generation. Additionally, a user-selectable digital data acquisition functionality provides diagnostic and troubleshoot access points, a new feature which is very useful in a digital system. The scaled-down prototype implements frequency program, radial steering, phase and radial loops capabilities and it has been tested in CERN's PS Booster (PSB) dur...

Status of the Upgrade of the CERN PS Booster

CERN Document Server

Hanke, K; Angoletta, M; Bartmann, W; Bartolome, S; Benedetto, E; Bertone, C; Blas, A; Bonnal, P; Borburgh, J; Bozzini, D; Butterworth, A; Carli, C; Carlier, E; Cole, J; Dahlen, P; Delonca, M; Dobers, T; Findlay, A; Froeschl, R; Hansen, J; Hay, D; Jensen, S; Lacroix, J; Le Roux, P; Lopez Hernandez, L; Maglioni, C; Masi, A; Mason, G; Mathot, S; Mikulec, B; Muttoni, Y; Newborough, A; Nisbet, D; Olek, S; Paoluzzi, M; Perillo-Marcone, A; Pittet, S; Puccio, B; Raginel, V; Riffaud, B; Ruehl, I; Sarrió Martínez, A; Tan, J; Todd, B; Venturi, V; Weterings, W

2013-01-01

The CERN PS Booster (PSB) is presently undergoing an ambitious consolidation and upgrade program within the frame of the LHC Injectors Upgrade (LIU) project. This program comprises a new injection scheme for H- ions from CERN’s new Linac4, the replacement of the main RF systems and an energy upgrade of the PSB rings from 1.4 to 2 GeV which includes the replacement of the main magnet power supply as well as the upgrade of the extraction equipment. This paper describes the status and plans of this work program.

Study of an energy upgrade of the CERN PS Booster

CERN Document Server

Hanke, K; Angoletta, M E; Bartmann, W; Bartolome, S; Bertone, C; Blas, A; Borburgh, J; Bozzini, D; Butterworth, A; Carli, C; Dahlen, P; Dobers, T; Findlay, A; Folch, R; Gilbert, N; Hansen, J; Hermanns, T; Jensen, S; Le Roux, P; Lopez-Hernandez, L A; Mahner, E; Masi, A; Mikulec, B; Muttoni, Y; Newborough, A; Nisbet, D; Nonis, M; Olek, S; Paoluzzi, M; Pittet, S; Puccio, B; Raginel, V; Ruehl, I; Tan, J; Todd, B; Weterings, W; Widorski, W

2011-01-01

CERN’s LHC injector chain will have to deliver beams with ultimate brilliance as the LHC is heading for increased luminosity in the coming years. In order to overcome bottlenecks in the injector chain, an increase of the beam transfer energy from the CERN Proton Synchrotron Booster (PSB) to the Proton Synchrotron (PS) has been investigated as a possible upgrade scenario. This paper gives an overview of the technical solutions and summarizes the conclusions of the feasibility study.

Autonomous booster device of a safety valve

International Nuclear Information System (INIS)

Namand, H.

1983-01-01

The invention concerns an autonomous booster device of a protection safety valve of a pressure vessel. The valve comprises a hollow structure, a seat connected with a mobile flap forming one piece with a stem and a calibration spring bearing on the stem and on the valve structure to maintain the flap bearing on the seat. The stem of the flap is prolongated in a box forming one piece with the valve structure and receives an added push of a spring. The box acts as a pressure device of which the piston can exercise on the stem a push opposite to and larger than the spring one. The feeding device of the pressure box is finally described in detail [fr

Technology for low cost solid rocket boosters.

Science.gov (United States)

Ciepluch, C.

1971-01-01

A review of low cost large solid rocket motors developed at the Lewis Research Center is given. An estimate is made of the total cost reduction obtainable by incorporating this new technology package into the rocket motor design. The propellant, case material, insulation, nozzle ablatives, and thrust vector control are discussed. The effect of the new technology on motor cost is calculated for a typical expandable 260-in. booster application. Included in the cost analysis is the influence of motor performance variations due to specific impulse and weight changes. It is found for this application that motor costs may be reduced by up to 30% and that the economic attractiveness of future large solid rocket motors will be improved when the new technology is implemented.

Monitoring of the booster biocide dichlofluanid in water and marine sediment of Greek marinas

NARCIS (Netherlands)

Hamwijk, C.; Schouten, A.; Foekema, E.M.; Ravensberg, J.C.; Collombon, M.T.; Schmidt, K.; Kugler, M.

2005-01-01

Dichlofluanid (N-dichlorofluoromethylthio-N′-dimethyl-N- phenylsulphamide) is used as booster biocide in antifouling paints. The occurrence of dichlofluanid and its metabolite DMSA (N′-dimethyl-N-phenyl- sulphamide) was monitored in seawater and marine sediment from three Greek marinas. Seawater and

Main cycle controls for the AGS Booster synchrotron

International Nuclear Information System (INIS)

Culwick, B.B.; Yen, S.

1991-01-01

The AGS Booster is a separated function synchrotron with the main excitation coils of the dipoles and quadrupoles connected electrically in series. This circuit is driven by a complex modular power supply with current and voltage reference functions to obtain the desired magnetic fields as a function of time. The dipole cycle is defined by algebraic functions specifying the desired field profile as a function of time. These functions are processed through successive phases to convert to the signals needed to provide the power supply with one current and six voltage references. The user interface and algorithms to derive the control variables are described. 4 refs., 3 figs

Summary of the 70 GeV Booster Group

International Nuclear Information System (INIS)

Makdisi, Y.; Khiari, F.

1985-06-01

The energy range of the 70 GeV SSC booster makes it difficult to employ a single technique for preserving the beam polarization. Results of DEPOL calculations show that the expected resonance strengths are below the .5 x 10 -1 level, which poses no problem for resonance jumping. It was found that a single adiabatically energized Siberian snake will not significantly depolarize the beam. Thus one good solution to the mixing problem is that the snake magnets be energized during the acceleration cycle reaching maximum operating value at 20 GeV, where they take over the resonance jumping role. The possibility of adiabatically energizing two snakes was found to be feasible

Long-term evaluation of mucosal and systemic immunity and protection conferred by different polio booster vaccines.

Science.gov (United States)

Xiao, Yuhong; Daniell, Henry

2017-09-25

Oral polio vaccine (OPV) and Inactivated Polio Vaccine (IPV) have distinct advantages and limitations. IPV does not provide mucosal immunity and introduction of IPV to mitigate consequences of circulating vaccine-derived polio virus from OPV has very limited effect on transmission and OPV campaigns are essential for interrupting wild polio virus transmission, even in developed countries with a high coverage of IPV and protected sewer systems. The problem is magnified in many countries with limited resources. Requirement of refrigeration for storage and transportation for both IPV and OPV is also a major challenge in developing countries. Therefore, we present here long-term studies on comparison of a plant-based booster vaccine, which is free of virus and cold chain with IPV boosters and provide data on mucosal and systemic immunity and protection conferred by neutralizing antibodies. Mice were primed subcutaneously with IPV and boosted orally with lyophilized plant cells containing 1μg or 25μg polio viral protein 1 (VP1), once a month for three months or a single booster one year after the first prime. Our results show that VP1-IgG1 titers in single or double dose IPV dropped to background levels after one year of immunization. This decrease correlated with >50% reduction in seropositivity in double dose and <10% seropositivity in single dose IPV against serotype 1. Single dose IPV offered no or minimal protection against serotype 1 and 2 but conferred protection against serotype 3. VP1-IgA titers were negligible in IPV single or double dose vaccinated mice. VP1 antigen with two plant-derived adjuvants induced significantly high level and long lasting VP1-IgG1, IgA and neutralizing antibody titers (average 4.3-6.8 log2 titers). Plant boosters with VP1 and plant derived adjuvants maintained the same level titers from 29 to 400days and conferred the same level of protection against all three serotypes throughout the duration of this study. Even during period, when

FCC-ee Pre-Booster Accelerators

CERN Document Server

Ogur, S; Zimmermann, F

2017-01-01

CERN’s ambitious new project, Future Circular Collider-ee, will have four operations as Z, W, H, and tt factories covering energies from 45.6 to 175 GeV. The main challenge of Z-operation is to achieve currents as high as 1450 mA; this will depend heavily on the injector. For this reason, we conclude that we need a high bunch charge of 3.3 × 1010, for both e− and e+, and fill 91 500 of each of those bunches into the collider. To achieve the goal, we have designed an S-band (2.856 GHz) normal conducting electron linac up to 6 GeV, which we will use to create and accelerate both electrons and positrons. Positrons will be created inside the linac at 4.46 GeV, will be accelerated up to 1.54 GeV at the linac, and will then be transferred to the designed damping ring. In this paper, we present the designed linac, damping ring, and the operational requirements of the 100 km booster.

Suppression of transverse instabilities by fast feedback in the Fermilab booster

International Nuclear Information System (INIS)

Ankenbrandt, C.; Higgins, E.F. Jr.; Johnson, R.P.

1977-01-01

Systems to damp radial and vertical instabilities of individual rf bunches in the Fermilab Booster are being implemented. The positions of individual bunches are derived from stripline pickups. The position information is transmitted over a variable delay, amplified, and applied to deflectors after one almost complete revolution, 6.25 horizontal and 6.75 vertical betatron wavelengths downstream of the pickup. Motivation, system concepts, design considerations, and initial operating experience are described

Efficacy and Duration of Immunity after Yellow Fever Vaccination: Systematic Review on the Need for a Booster Every 10 Years

Science.gov (United States)

Gotuzzo, Eduardo; Yactayo, Sergio; Córdova, Erika

2013-01-01

Current regulations stipulate a yellow fever (YF) booster every 10 years. We conducted a systematic review of the protective efficacy and duration of immunity of YF vaccine in residents of disease-endemic areas and in travelers to assess the need for a booster in these two settings and in selected populations (human immunodeficiency virus–infected persons, infants, children, pregnant women, and severely malnourished persons). Thirty-six studies and 22 reports were included. We identified 12 studies of immunogenicity, 8 of duration of immunity, 8 of vaccine response in infants and children, 7 of human-immunodeficiency virus–infected persons, 2 of pregnant women, and 1 of severely malnourished children. Based on currently available data, a single dose of YF vaccine is highly immunogenic and confers sustained life-long protective immunity against YF. Therefore, a booster dose of YF vaccine is not needed. Special considerations for selected populations are detailed. PMID:24006295

Long-term persistence of immunity and B-cell memory following Haemophilus influenzae type B conjugate vaccination in early childhood and response to booster.

Science.gov (United States)

Perrett, K P; John, T M; Jin, C; Kibwana, E; Yu, L-M; Curtis, N; Pollard, A J

2014-04-01

Protection against Haemophilus influenzae type b (Hib), a rapidly invading encapsulated bacteria, is dependent on maintenance of an adequate level of serum antibody through early childhood. In many countries, Hib vaccine booster doses have been implemented after infant immunization to sustain immunity. We investigated the long-term persistence of antibody and immunological memory in primary-school children following infant (with or without booster) Hib vaccination. Anti-polyribosylribitol phosphate (PRP) immunoglobulin G (IgG) concentration and the frequency of circulating Hib-specific memory B cells were measured before a booster of a Hib-serogroup C meningococcal (MenC) conjugate vaccine and again 1 week, 1 month, and 1 year after the booster in 250 healthy children aged 6-12 years in an open-label phase 4 clinical study. Six to 12 years following infant priming with 3 doses of Hib conjugate vaccine, anti-PRP IgG geometric mean concentrations were 3.11 µg/mL and 0.71 µg/mL and proportions with anti-PRP IgG ≥1.0 µg/mL were 79% and 43% in children who had or had not, respectively, received a fourth Hib conjugate vaccine dose (mean age, 3.9 years). Higher baseline and post-Hib-MenC booster responses (anti-PRP IgG and memory B cells) were found in younger children and in those who had received a fourth Hib dose. Sustained Hib conjugate vaccine-induced immunity in children is dependent on time since infant priming and receipt of a booster. Understanding the relationship between humoral and cellular immunity following immunization with conjugate vaccines may direct vaccine design and boosting strategies to sustain individual and population immunity against encapsulated bacteria in early childhood. Clinical Trials Registration ISRCTN728588998.

Software environment and configuration for the DSP controlled NSLS booster power supplies

International Nuclear Information System (INIS)

Olsen, R.; Dabrowski, J.; Murray, J.

1993-01-01

The booster at the NSLS is being upgraded from 0.75 to 2 pulses per second by means of the installation of new dipole, quadrupole, and sextupole power supplies. The control system of these power supplies employs general purpose digital signal processing modules, and therefore, software support is required. This paper outlines the development system configuration, and the software environment

Responses of platinum, vanadium and cobalt self-powered flux detectors near simulated booster rods in a ZED-2 mockup of a Bruce reactor core

International Nuclear Information System (INIS)

French, P.M.; Shields, R.B.; Kroon, J.C.

1978-02-01

The static responses of Pt, V and Co self-powered detectors have been compared with copper-foil neutron activation profiles in reference and perturbed Bruce reactor core mockups assembled in the ZED-2 test reactor at Chalk River Nuclear Laboratories. The results indicate that the normalized response of each self-powered detector is an accurate measure of the thermal-neutron flux at locations greater than one lattice pitch from either a booster rod or the core boundary. They indicate that, in the Bruce booster/detector configuration, the normalized static Pt response overestimates the neutron flux by less than 3.5% upon full booster-rod insertion. (author)

Operational status of the AGS Booster Main Ring Magnet Power Supply

International Nuclear Information System (INIS)

Soukas, A.; Bannon, M.; Geller, J.; McNerney, A.J.; Sandberg, J.; Toldo, F.; Zhang, S.Y.

1992-01-01

The Booster is a multipurpose accelerator interposed between a 200 MeV linac, a pair of 15 MV Tandem Van deGraaf accelerators, and the AGS. It can operate on slow cycles of 0.3 Hertz pulse repetition frequency up to a maximum of 7.5 Hertz. The different cycles, from long front porches for long injection or accumulation periods or flattops for slow extraction, to normal fast extraction cycles, accommodate protons, heavy ions (h.i.) and polarized protons. One of the systems enabling the flexible Booster operation is the Main Ring Magnet Power Supply (MRPS) system. It consist of a series connection of six, 1000 volt, multiphase rectifiers together with by pass switches. Two of the six operate at currents up to 6 kA and the rest up to 3 kA. All bypass switches are rated for 6 kA. The system is equipped with passive, damped LCRC filters as well as an active transformer coupled correction system. The MRPS is connected directly to the Long Island 69 Kv bus via a dedicated 20 MVA transformer. The choice of a series of modules enables the very flexible cycle generation and at the same time minimizes the deleterious effects of power factor and harmonics on the ac lines

Investigation of the McDonnell-Douglas orbiter and booster shuttle models in proximity at Mach numbers 2.0 to 6.0. Volume 7: Proximity data at Mach 4 and 6, interference free and launch vehicle data

Science.gov (United States)

Trimmer, L. L.; Love, D. A.; Decker, J. P.; Blackwell, K. L.; Strike, W. T.; Rampy, J. M.

1972-01-01

Aerodynamic data obtained from a space shuttle abort stage separation wind tunnel test are presented. The .00556 scale models of the orbiter and booster configuration were tested in close proximity using dual balances during the time period of April 21 to April 27 1971. Data were obtained for both booster and orbiter over an angle of attack range from -10 to 10 deg for zero degree sideslip angle. The models were tested at several relative incidence angles and separation distances and power conditions. Plug nozzles utilizing air were used to simulate booster and orbiter plumes at various altitudes along a nominal ascent trajectory. Powered conditions were 100, 50, 25 and 0 percent of full power for the orbiter and 100, 50 and 0 percent of full power for the booster. Pitch control effectiveness data were obtained for both booster and orbiter with power on and off. In addition, launch vehicle data with and without booster power were obtained utilizing a single balance in the booster model. Data were also obtained with the booster canard off in close proximity and for the launch configuration.

Development Of Radioimmunoassay For Prolactin HORMONE Using Solid Phase Magnetic Particles

International Nuclear Information System (INIS)

SHAFIK, H.M.; MEHANY, N.L.

2009-01-01

The preparation and development of primary reagents of prolactin (PRL) radioimmunoassay (RIA) technique using solid phase magnetic particles with low cost is considered to be the main objective of the present study. The production of polyclonal antibodies was undertaken by immunizing four female New-Zealand rabbits through primary injection and four booster doses subcutaneously. The preparation of 125 I-prolactin radiotracer was carried out using chloramine-T. The preparation of standard prolactin was undertaken by preparing stock standard solution of prolactin and diluted with assay buffer. Activation and coupling of low magnetizable particles with the purified anti-PRL was carried out. Optimization and validation of the assay were carried out. The results obtained provide a highly sensitive, specific and accurate RIA system of PRL. In conclusion, this assay could be used in diagnosis of galactorrhea, prolactinoma, visual impairment and diagnosis of infertility in males and females.

Shielding for a tandem accelerator coupled to linac booster

International Nuclear Information System (INIS)

Bhattacharyya, S.; Bisht, J.S.; Venkataraman, G.

1996-01-01

Shielding calculation for the Beam-Hall-II of pelletron facility, augmented with linac booster in its phase-II at Nuclear Science Centre, New Delhi, has been done. An estimate is obtained by reduction factor method considering source radiation of monoenergetic neutrons, which is then compared with the detail computation using computer code ALICE considering total energy and angular distribution of neutrons. Another code ASFIT is used to take into account the build up of gamma dose from (n, gamma) reactions within the concrete shield incorporating new radiation weighting factors as recommended by ICRP-60. (author). 8 refs., 2 figs

Performance of the ramping power supplies for the APS booster synchrotron

International Nuclear Information System (INIS)

Carwardine, J.A.; Milton, S.V.; McGhee, D.G.

1995-01-01

The Advanced Photon Source (APS) booster ramp cycle is completed within 250ms and repeated at 2Hz. Separate phase-controlled power supplies deliver current to each of the dipole, quadrupole, and sextupole magnet families. Tracking requirements are particularly challenging because of the fast (non-resonant) ramp. In order to meet the requirements, both conventional regulation and cycle-to-cycle adaptation are used. The power supply system and its performance are described

Performance of ultra low temperature district heating systems with utility plant and booster heat pumps

DEFF Research Database (Denmark)

Ommen, Torben Schmidt; Thorsen, Jan Eric; Markussen, Wiebke Brix

2017-01-01

The optimal integration of booster heat pumps in ultra low temperature district heating (ULTDH) was investigated and compared to the performance of low temperature district heating. Two possible heat production technologies for the DH networks were analysed, namely extraction combined heat...... temperature and the heat consumption profile. For reference conditions, the optimal return of ULTDH varies between 21 °C and 27 °C. When using a central HP to supply the DH system, the resulting coefficient of system performance (COSP) was in the range of 3.9 (-) to 4.7 (-) for equipment with realistic...... component efficiencies and effectiveness, when including the relevant parameters such as DH system pressure and heat losses. By using ULTDH with booster HPs, performance improvements of 12% for the reference calculations case were found, if the system was supplied by central HPs. Opposite results were found...

IEEE 1394 CAMERA IMAGING SYSTEM FOR BROOKHAVENS BOOSTER APPLICATION FACILITY BEAM DIAGNOSTICS

International Nuclear Information System (INIS)

BROWN, K.A.; FRAK, B.; GASSNER, D.; HOFF, L.; OLSEN, R.H.; SATOGATA, T.; TEPIKIAN, S.

2002-01-01

Brookhaven's Booster Applications Facility (BAF) will deliver resonant extracted heavy ion beams from the AGS Booster to short-exposure fixed-target experiments located at the end of the BAF beam line. The facility is designed to deliver a wide range of heavy ion species over a range of intensities from 10 3 to over 10 8 ions/pulse, and over a range of energies from 0.1 to 3.0 GeV/nucleon. With these constraints we have designed instrumentation packages which can deliver the maximum amount of dynamic range at a reasonable cost. Through the use of high quality optics systems and neutral density light filters we will achieve 4 to 5 orders of magnitude in light collection. By using digital IEEE1394 camera systems we are able to eliminate the frame-grabber stage in processing and directly transfer data at maximum rates of 400 Mb/set. In this note we give a detailed description of the system design and discuss the parameters used to develop the system specifications. We will also discuss the IEEE1394 camera software interface and the high-level user interface

Pulsed neutron source very intense, Booster

International Nuclear Information System (INIS)

Abbate, J.M.

1978-09-01

A compact Accelerator-Booster (fast, pulsed and modulate reactivity research reactor) is a new and appropriate conception to use as a very intense thermal neutrons source. Its definition and feasibility have been already described in several studies showing its relative advantages in comparison with others kinds of facilities. This work, wich is part of one of those studies, contains a general analysis on the meis facility parameters and core and shielding theoretical calculations. The following results were obtained: Selection and test of a calculation system suitable to use in compact fast reactors; Development a method to perform estimations in some safety and shielding problems and obtainment of adequate theoretical predictions on the general performance. Moreover, final results for importent parameters of the feasibility study and predesign (critical mass and volume, lifetime, etc.) and others related to the use of plutonium oxide as fuel are given and then evaluations of different basic functions are showed. (author) [es

The PS Booster, PS and SPS Magnets for the next 25 years

CERN Document Server

Tommasini, D

2010-01-01

This note provides information and analysis on the present status of the magnets installed in the CERN Proton Synchrotron Booster (PSB), the Proton Synchrotron (PS) and the Super Proton Synchrotron (SPS) in view of their possible operation for the next 25 years. The note does not cover the magnets installed in the transfer lines, neither it covers the fast injection/extraction magnets (septa and kickers).

Neutralization antibody response to booster/priming immunization with new equine influenza vaccine in Japan.

Science.gov (United States)

Yamanaka, Takashi; Nemoto, Manabu; Bannai, Hiroshi; Tsujimura, Koji; Matsumura, Tomio; Kokado, Hiroshi; Gildea, Sarah; Cullinane, Ann

2018-03-02

Equine influenza (EI) vaccine has been widely used. However, the causative EI virus (H3N8) undergoes continuous antigenic drift, and the vaccine strains must be periodically reviewed and if necessary, updated to maintain vaccine efficacy against circulating viruses. In 2016, the Japanese vaccine was updated by replacing the old viruses with the Florida sub-lineage Clade (Fc) 2 virus, A/equine/Yokohama/aq13/2010 (Y10). We investigated the virus neutralization (VN) antibody response to Fc2 viruses currently circulating in Europe, after booster or primary immunization with the new vaccine. These European viruses have the amino acid substitution A144V or I179V of the hemagglutinin. In horses that had previously received a primary course and bi-annual boosters with the old vaccine booster, immunization with the updated vaccine increased the VN antibody levels against the European Fc2 viruses as well as Y10. There were no significant differences in the VN titers against Y10 and the Fc2 viruses with A144V or I179V substitution in horses that had received a primary course of the updated vaccine. However, a mixed primary course where the first dose was the old vaccine and the second dose was the updated vaccine, reduced VN titers against the European viruses compared to that against Y10. In summary, the new vaccine affords horses protective level of VN titers against the Fc2 viruses carrying A144V or I179V substitution, but our results suggest that the combination of the old and new vaccines for primary immunization would not be optimum.

Electronics for damping transverse instabilities for the Fermilab booster synchrotron

International Nuclear Information System (INIS)

Higgins, E.F. Jr.

1977-01-01

Transverse instabilities are controlled by an active beam damper which corrects the orbit of individual proton bunches in the Fermilab booster synchrotron. The corrective signals, which are in reality processed versions of the beam pick-up data, are applied to the beam via power amplifier/deflector electrodes approximately one turn after sensing the bunch position. The electronic systems of the damper are configured as a closed-loop feedback arrangement. A brief outline is given of the overall damper system configuration, and the beam position detector, coaxial cable delay system, and data receiver are described

Air Force Reusable Booster System: A Quick-look, Design Focused Modeling and Cost Analysis Study

Science.gov (United States)

Zapata, Edgar

2011-01-01

This paper presents a method and an initial analysis of the costs of a reusable booster system (RBS) as envisioned by the US Department of Defense (DoD) and numerous initiatives that form the concept of Operationally Responsive Space (ORS). This paper leverages the knowledge gained from decades of experience with the semi-reusable NASA Space Shuttle to understand how the costs of a military next generation semi-reusable space transport might behave in the real world - and how it might be made as affordable as desired. The NASA Space Shuttle had a semi-expendable booster, that being the reusable Solid Rocket MotorslBoosters (SRMlSRB) and the expendable cryogenic External Tank (ET), with a reusable cargo and crew capable orbiter. This paper will explore DoD concepts that invert this architectural arrangement, using a reusable booster plane that flies back to base soon after launch, with the in-space elements of the launch system being the expendable portions. Cost estimating in the earliest stages of any potential, large scale program has limited usefulness. As a result, the emphasis here is on developing an approach, a structure, and the basic concepts that could continue to be matured as the program gains knowledge. Where cost estimates are provided, these results by necessity carry many caveats and assumptions, and this analysis becomes more about ways in which drivers of costs for diverse scenarios can be better understood. The paper is informed throughout with a design-for-cost philosophy whereby the design and technology features of the proposed RBS (who and what, the "architecture") are taken as linked at the hip to a desire to perform a certain mission (where and when), and together these inform the cost, responsiveness, performance and sustainability (how) of the system. Concepts for developing, acquiring, producing or operating the system will be shown for their inextricable relationship to the "architecture" of the system, and how these too relate to costs

Septum magnets for booster ring

International Nuclear Information System (INIS)

Mishra, R.K.; Mhaskar, S.P.; Ramamurthi, S.S.

1991-01-01

Synchrotron radiation source facility in CAT will employ one septum magnet for the injection of 20 MeV electron beam from the microtron and another septum magnet for the extraction of 700 MeV electron beam from the booster synchrotron. The septum is a boundary that combines or separates the beam by providing the different deflecting fields on either side of this boundary. In this magnet, septum sheet must be as thin as possible to reduce the beam losses and fringing field must be very low. Two septum magnets have been designed, one has 2 mm thick septum sheet for the injection of beam and another one has 3 mm thick septum sheet for the extraction of beam. The field strength of injection and extraction septum magnets, is 0.15 T and 0.88 T respectively. The fringing field near the septum sheet is only 10 G and 30 G for the injection and extraction magnet respectively. The field simulation has been done by computer code PANDIRA. The field homogeneity within gap is ± 0.1%. The design details are discussed in this paper. (author). 4 refs., 1 tab., 1 fig

State Machine Modeling of the Space Launch System Solid Rocket Boosters

Science.gov (United States)

Harris, Joshua A.; Patterson-Hine, Ann

2013-01-01

The Space Launch System is a Shuttle-derived heavy-lift vehicle currently in development to serve as NASA's premiere launch vehicle for space exploration. The Space Launch System is a multistage rocket with two Solid Rocket Boosters and multiple payloads, including the Multi-Purpose Crew Vehicle. Planned Space Launch System destinations include near-Earth asteroids, the Moon, Mars, and Lagrange points. The Space Launch System is a complex system with many subsystems, requiring considerable systems engineering and integration. To this end, state machine analysis offers a method to support engineering and operational e orts, identify and avert undesirable or potentially hazardous system states, and evaluate system requirements. Finite State Machines model a system as a finite number of states, with transitions between states controlled by state-based and event-based logic. State machines are a useful tool for understanding complex system behaviors and evaluating "what-if" scenarios. This work contributes to a state machine model of the Space Launch System developed at NASA Ames Research Center. The Space Launch System Solid Rocket Booster avionics and ignition subsystems are modeled using MATLAB/Stateflow software. This model is integrated into a larger model of Space Launch System avionics used for verification and validation of Space Launch System operating procedures and design requirements. This includes testing both nominal and o -nominal system states and command sequences.

FY2014 Parameters for Helions and Gold Ions in Booster, AGS, and RHIC

Energy Technology Data Exchange (ETDEWEB)

Gardner, C. J. [Brookhaven National Lab. (BNL), Upton, NY (United States). Collider-Accelerator Dept.

2014-08-15

The nominal parameters for helions (helion is the bound state of two protons and one neutron, the nucleus of a helium-3 atom) and gold ions in Booster, AGS, and RHIC are given for the FY2014 running period. The parameters are found using various formulas to derive mass, helion anomalous g-factor, kinetic parameters, RF parameters, ring parameters, etc..

Off-line tests of superconducting resonators of the JAERI tandem booster

International Nuclear Information System (INIS)

Shibata, Michihiro; Ishii, Tetsuro; Takeuchi, Suehiro

1993-01-01

The JAERI tandem booster linac, which consists of 46 superconducting quarter wave resonators, is under construction. Off-line tests for resonators were performed. Accelerating field levels of 7MV/m were obtained at an rf input of 4W with most resonators. A maximum field level of 12.7MV/m was obtained. The Q-value was degraded when resonators were cooled down slowly around a temperature of 120K. We investigated this phenomenon by changing the cooling rate. (author)

Elements of the system for RF power input into linear accelerator-injector for booster

International Nuclear Information System (INIS)

Mazurov, E.V.; Mal'tsev, I.G.; Shalashov, I.M.

1981-01-01

The elements of the original system for RF power input into 30 MeV linear accelerator-injector for the IHEP proton synchrotron booster are considered. A 3 dB coaxial directional coupler (T-bridge) is describedd. The characteristics of the bridge containing elements and the parameters of ballast matched load are given [ru

A randomised controlled trial and cost-effectiveness evaluation of "booster" interventions to sustain increases in physical activity in middle-aged adults in deprived urban neighbourhoods

Directory of Open Access Journals (Sweden)

Nicholl Jon

2010-01-01

Full Text Available Abstract Background Systematic reviews have identified a range of brief interventions which increase physical activity in previously sedentary people. There is an absence of evidence about whether follow up beyond three months can maintain long term physical activity. This study assesses whether it is worth providing motivational interviews, three months after giving initial advice, to those who have become more active. Methods/Design Study candidates (n = 1500 will initially be given an interactive DVD and receive two telephone follow ups at monthly intervals checking on receipt and use of the DVD. Only those that have increased their physical activity after three months (n = 600 will be randomised into the study. These participants will receive either a "mini booster" (n = 200, "full booster" (n = 200 or no booster (n = 200. The "mini booster" consists of two telephone calls one month apart to discuss physical activity and maintenance strategies. The "full booster" consists of a face-to-face meeting with the facilitator at the same intervals. The purpose of these booster sessions is to help the individual maintain their increase in physical activity. Differences in physical activity, quality of life and costs associated with the booster interventions, will be measured three and nine months from randomisation. The research will be conducted in 20 of the most deprived neighbourhoods in Sheffield, which have large, ethnically diverse populations, high levels of economic deprivation, low levels of physical activity, poorer health and shorter life expectancy. Participants will be recruited through general practices and community groups, as well as by postal invitation, to ensure the participation of minority ethnic groups and those with lower levels of literacy. Sheffield City Council and Primary Care Trust fund a range of facilities and activities to promote physical activity and variations in access to these between neighbourhoods will make it

Measurement of Reconstructed Charged Particle Multiplicities of Neutrino Interactions in MicroBooNE

Energy Technology Data Exchange (ETDEWEB)

Rafique, Aleena [Kansas State Univ., Manhattan, KS (United States)

2017-09-25

Here, we compare the observed charged particle multiplicity distributions in the MicroBooNE liquid argon time projection chamber from neutrino interactions in a restricted final state phase space to predictions of this distribution from several GENIE models. The measurement uses a data sample consisting of neutrino interactions with a final state muon candidate fully contained within the MicroBooNE detector. These data were collected in 2015-2016 with the Fermilab Booster Neutrino Beam (BNB), which has an average neutrino energy of 800 MeV, using an exposure corresponding to 5e19 protons-on-target. The analysis employs fully automatic event selection and charged particle track reconstruction and uses a data-driven technique to determine the contribution to each multiplicity bin from neutrino interactions and cosmic-induced backgrounds. The restricted phase space employed makes the measurement most sensitive to the higher-energy charged particles expected from primary neutrino-argon collisions and less sensitive to lower energy protons expected to be produced in final state interactions of collision products with the target argon nucleus.

Formation of a single-bunch beam in the booster synchrotron at SPring-8

CERN Document Server

Suzuki, H; Ego, H; Hara, M; Hosoda, N; Kawashima, Y; Ohashi, Y; Ohshima, T; Tani, N; Yabashi, M; Yonehara, H

2000-01-01

In order to fill a radio frequency (rf) bucket with an electron beam in the storage ring at SPring-8, an rf knockout system was installed in the booster synchrotron. With this system, the energy of the electron beam injected from the linac was increased from 1 to 8 GeV. The time width of multi-bunch beams from the linac operated at 2856 MHz rf can be selected as 1 or 40 ns. The beam injected from the linac is distributed in rf buckets of the booster synchrotron operated at 508.58 MHz rf. To fill a single rf bucket with a beam, the rf knockout system is operated at a minimum beam energy of 1 GeV. By using the rf knockout system, the electron beam is effectively kept in a single rf bucket. Then the beam is injected into a targeted rf bucket in the storage ring with a precise timing system. The beam intensity of satellite rf buckets in the storage ring was measured with a photon counting method and determined to be 10 sup - sup 6 less than that of the main rf bucket. In this paper, we describe the rf knockout sy...

The AGS Booster beam loss monitor system

International Nuclear Information System (INIS)

Beadle, E.R.; Bennett, G.W.; Witkover, R.L.

1991-01-01

A beam loss monitor system has been developed for the Brookhaven National Laboratory Booster accelerator, and is designed for use with intensities of up to 1.5 x 10 13 protons and carbon to gold ions at 50-3 x 10 9 ions per pulse. This system is a significant advance over the present AGS system by improving the sensitivity, dynamic range, and data acquisition. In addition to the large dynamic range achievable, it is adaptively shifted when high losses are detected. The system uses up to 80 argon filled ion chambers as detectors, as well as newly designed electronics for processing and digitizing detector outputs. The hardware simultaneously integrates each detector output, interfaces to the beam interrupt systems, and digitizes all 80 channels to 21 bits at 170 KHz. This paper discuses the design, construction, and operation of the system. 4 refs., 2 figs

Tha AGS Booster high frequency rf system

International Nuclear Information System (INIS)

Sanders, R.; Cameron, P.; Damn, R.

1988-01-01

A high level rf system, including a power amplifier and cavity has been designed for the AGS Booster. It covers a frequency range of 2.4 to 4.2 Mhz and will be used to accelerate high intensity proton, and low intensity polarized proton beams to 1.5 GeV and heavy ions to 0.35 GeV per nucleon. A total accelerating voltage of up to 90kV will be provided by two cavities, each having two gaps. The internally cross-coupled, pushpull cavities are driven by an adjacently located power amplifier. In order to accommodate the high beam intensity, up to 0.75 /times/ 10 13 protons per bunch, a low plate resistance power tetrode is used. The tube anode is magnetically coupled to one of the cavity's two paralleled cells. The amplifier is a grounded cathode configuration driven by a remotely located solid state amplifier

Status of the Argonne superconducting-linac heavy-ion energy booster

International Nuclear Information System (INIS)

Aron, J.; Benaroya, R.; Bollinger, L.M.; Clifft, B.E.; Henning, W.; Johnson, K.W.; Nixon, J.M.; Markovich, P.; Shepard, K.W.

1979-01-01

A superconducting linac is being constructed to provide an energy booster for heavy ions from an FN tandem. By late 1980 the linac will consist of 24 independently-phased superconducting resonators, and will provide an effective accelerating potential of more than 25 MV. While the linac is under construction, completed sections are being used to provide useful beam for nuclear physics experiments. In the most recent run with beam (June 1979), an eight resonator array provided an effective accelerating potential of 9.3 MV. Operation of a 12 resonator array is scheduled to begin in October 1979

Status of the Argonne superconducting-linac heavy-ion energy booster

Energy Technology Data Exchange (ETDEWEB)

Aron, J.; Benaroya, R.; Bollinger, L.M.; Clifft, B.E.; Henning, W.; Johnson, K.W.; Nixon, J.M.; Markovich, P.; Shepard, K.W.

1979-01-01

A superconducting linac is being constructed to provide an energy booster for heavy ions from an FN tandem. By late 1980 the linac will consist of 24 independently-phased superconducting resonators, and will provide an effective accelerating potential of more than 25 MV. While the linac is under construction, completed sections are being used to provide useful beam for nuclear physics experiments. In the most recent run with beam (June 1979), an eight resonator array provided an effective accelerating potential of 9.3 MV. Operation of a 12 resonator array is scheduled to begin in October 1979.

Multipole Stack for the 800 MeV PS Booster

CERN Multimedia

1975-01-01

The 800 MeV PS Booster had seen first beam in its 4 superposed rings in 1972, routine operation began in 1973. In the strive for ever higher beam intensities, the need for additional multipole lenses became evident. After detailed studies, the manufacture of 8 stacks of multipoles was launched in 1974. Each stack consists of 4 superposed multipoles and each multipole has 4 concentric shells. From the innermost to the outermost shell, Type A contains octupole, skew-octupole, sextupole, skew-sextupole. Type B contains skew-octupole, skew-sextupole, vertical dipole, horizontal dipole. Completion of installation in 1976 opened the way to higher beam intensities. M. Battiaz is seen here with a multipole stack and its many electrical connections.

Booster effect of canine distemper, canine parvovirus infection and infectious canine hepatitis combination vaccine in domesticated adult dogs.

Science.gov (United States)

Taguchi, Masayuki; Namikawa, Kazuhiko; Maruo, Takuya; Orito, Kensuke; Lynch, Jonathan; Tsuchiya, Ryo; Sahara, Hiroeki

2012-08-01

Domesticated adult dogs with antibody titer classified as below 'high' to one or more of canine distemper virus (CDV), canine parvovirus type-2 (CPV-2) and canine adenovirus type-1 (CAdV-1) were then given an additional inoculation, and the effectiveness of this booster evaluated 2 months later. Consequently, CDV and CAdV-1 antibody titer experienced a significant increase, but the same effect was not observed in the antibody titer of CPV-2. These findings suggest that with additional inoculation, a booster effect may be expected in increasing antibody titers for CDV and CAdV-1, but it is unlikely to give an increase in CPV-2 antibody titer. © 2012 The Societies and Blackwell Publishing Asia Pty Ltd.

MCNPX, MONK, and ERANOS analyses of the YALINA Booster subcritical assembly

Energy Technology Data Exchange (ETDEWEB)

Talamo, Alberto, E-mail: alby@anl.go [Argonne National Laboratory, 9700 S. Cass Avenue, Argonne, IL 60439 (United States); Gohar, Y.; Aliberti, G.; Cao, Y.; Smith, D.; Zhong, Z. [Argonne National Laboratory, 9700 S. Cass Avenue, Argonne, IL 60439 (United States); Kiyavitskaya, H.; Bournos, V.; Fokov, Y.; Routkovskaya, C.; Serafimovich, I. [Joint Institute for Power and Nuclear Research - Sosny, National Academy of Sciences of Belarus, 99 Acad. Krasin Str., Minsk 220109 (Belarus)

2011-05-15

This paper compares the numerical results obtained from various nuclear codes and nuclear data libraries with the YALINA Booster subcritical assembly (Minsk, Belarus) experimental results. This subcritical assembly was constructed to study the physics and the operation of accelerator-driven subcritical systems (ADS) for transmuting the light water reactors (LWR) spent nuclear fuel. The YALINA Booster facility has been accurately modeled, with no material homogenization, by the Monte Carlo codes MCNPX (MCNP/MCB) and MONK. The MONK geometrical model matches that of MCNPX. The assembly has also been analyzed by the deterministic code ERANOS. In addition, the differences between the effective neutron multiplication factor and the source multiplication factors have been examined by alternative calculational methodologies. The analyses include the delayed neutron fraction, prompt neutron lifetime, generation time, neutron flux profiles, and spectra in various experimental channels. The accuracy of the numerical models has been enhanced by accounting for all material impurities and the actual density of the polyethylene material used in the assembly (the latter value was obtained by dividing the total weight of the polyethylene by its volume in the numerical model). There is good agreement between the results from MONK, MCNPX, and ERANOS. The ERANOS results show small differences relative to the other results because of material homogenization and the energy and angle discretizations.The MCNPX results match the experimental measurements of the {sup 3}He(n,p) reaction rates obtained with the californium neutron source.

MCNPX, MONK, and ERANOS analyses of the YALINA Booster subcritical assembly

International Nuclear Information System (INIS)

Talamo, Alberto; Gohar, Y.; Aliberti, G.; Cao, Y.; Smith, D.; Zhong, Z.; Kiyavitskaya, H.; Bournos, V.; Fokov, Y.; Routkovskaya, C.; Serafimovich, I.

2011-01-01

This paper compares the numerical results obtained from various nuclear codes and nuclear data libraries with the YALINA Booster subcritical assembly (Minsk, Belarus) experimental results. This subcritical assembly was constructed to study the physics and the operation of accelerator-driven subcritical systems (ADS) for transmuting the light water reactors (LWR) spent nuclear fuel. The YALINA Booster facility has been accurately modeled, with no material homogenization, by the Monte Carlo codes MCNPX (MCNP/MCB) and MONK. The MONK geometrical model matches that of MCNPX. The assembly has also been analyzed by the deterministic code ERANOS. In addition, the differences between the effective neutron multiplication factor and the source multiplication factors have been examined by alternative calculational methodologies. The analyses include the delayed neutron fraction, prompt neutron lifetime, generation time, neutron flux profiles, and spectra in various experimental channels. The accuracy of the numerical models has been enhanced by accounting for all material impurities and the actual density of the polyethylene material used in the assembly (the latter value was obtained by dividing the total weight of the polyethylene by its volume in the numerical model). There is good agreement between the results from MONK, MCNPX, and ERANOS. The ERANOS results show small differences relative to the other results because of material homogenization and the energy and angle discretizations.The MCNPX results match the experimental measurements of the 3 He(n,p) reaction rates obtained with the californium neutron source.

Update on Risk Reduction Activities for a Liquid Advanced Booster for NASA's Space Launch System

Science.gov (United States)

Crocker, Andrew M.; Greene, William D.

2017-01-01

The stated goals of NASA's Research Announcement for the Space Launch System (SLS) Advanced Booster Engineering Demonstration and/or Risk Reduction (ABEDRR) are to reduce risks leading to an affordable Advanced Booster that meets the evolved capabilities of SLS and enable competition by mitigating targeted Advanced Booster risks to enhance SLS affordability. Dynetics, Inc. and Aerojet Rocketdyne (AR) formed a team to offer a wide-ranging set of risk reduction activities and full-scale, system-level demonstrations that support NASA's ABEDRR goals. During the ABEDRR effort, the Dynetics Team has modified flight-proven Apollo-Saturn F-1 engine components and subsystems to improve affordability and reliability (e.g., reduce parts counts, touch labor, or use lower cost manufacturing processes and materials). The team has built hardware to validate production costs and completed tests to demonstrate it can meet performance requirements. State-of-the-art manufacturing and processing techniques have been applied to the heritage F-1, resulting in a low recurring cost engine while retaining the benefits of Apollo-era experience. NASA test facilities have been used to perform low-cost risk-reduction engine testing. In early 2014, NASA and the Dynetics Team agreed to move additional large liquid oxygen/kerosene engine work under Dynetics' ABEDRR contract. Also led by AR, the objectives of this work are to demonstrate combustion stability and measure performance of a 500,000 lbf class Oxidizer-Rich Staged Combustion (ORSC) cycle main injector. A trade study was completed to investigate the feasibility, cost effectiveness, and technical maturity of a domestically-produced engine that could potentially both replace the RD-180 on Atlas V and satisfy NASA SLS payload-to-orbit requirements via an advanced booster application. Engine physical dimensions and performance parameters resulting from this study provide the system level requirements for the ORSC risk reduction test article

Feasibility for the Use of Flat Booster Reflectors in Various Photovoltaic Installations

OpenAIRE

Gelegenis, John Joachim; Axaopoulos, Petros; Misailidis, Stavros; Giannakidis, George; Samarakou, Maria; Bonaros, Bassilios

2016-01-01

The feasibility for the addition of flat booster reflectors to PV panels is techno-economically investigated for various applications (building attached PVs, ground installations, grid-connected or stand-alone units) and various PV types (mono-crystalline and amorphous silicon PV panels). A model developed to this aim is applied to optimize the parameters of the PV/reflector module and to evaluate its applicability according to the solar radiation data of Athens (Greece). The reflectors may l...

Charged-particle beam diagnostics for the Advanced Photon Source (APS)

International Nuclear Information System (INIS)

Lumpkin, A.H.; Decker, G.; Kahana, E.; Patterson, D.; Sellyey, W.; Wang, X.; Chung, Y.

1992-01-01

Plans, prototypes, and initial test results for the charged-particle beam (e - , e + ) diagnostic systems on the injector rings, their transport lines, and the storage ring for the Advanced Photon Source (APS) are presented. The APS will be a synchrotron radiation user facility with one of the world's brightest x-ray sources in the 10-keV to 100-keV regime. Its 200-MeV electron linac, 450-MeV positron linac, positron accumulator ring, 7-GeV booster synchrotron, 7-GeV storage ring, and undulator test lines will also demand the development and demonstration of key particle-beam characterization techniques over a wide range of parameter space. Some of these parameter values overlap or approach those projected for fourth generation light sources (linac-driven FELs and high brightness storage rings) as described at a recent workshop. Initial results from the diagnostics prototypes on the linac test stand operating at 45-MeV include current monitor data, beam loss monitor data, and video digitization using VME architecture

The AGS Booster high frequency rf system

International Nuclear Information System (INIS)

Sanders, R.T.; Cameron, P.; Eng, W.; Goldman, M.A.; Jablonski, E.; Kasha, D.; Keane, J.; McNerney, A.; Meth, M.; Plotkin, M.; Puglisi, M.; Ratti, A.; Spitz, R.

1991-01-01

A high level rf system, including a power amplifier and cavity, has been designed and built for the AGS Booster. It covers a frequency range of 2.4 to 4.2 MHz and will be used to accelerate high intensity protons. Low intensity polarized protons and heavy ions, to the 1.5 GeV level. A total accelerating voltage of up to 90 kV will be provided by two cavities, each having two gaps. The internally cross coupled, pushpull cavities are driven by an adjacently located power amplifier. In order to accommodate beam intensities up to 0.75 x 10 13 protons per bunch, a low plate resistance power tetrode is used. The tube anode is magnetically coupled to one of the cavity's two parallel cells. The amplifier is a grounded cathode configuration driven by a remotely located solid-state amplifier. It has been tested in the laboratory at full gap voltage with satisfactory results. 5 refs., 2 figs., 1 tab

Quantitative Index and Abnormal Alarm Strategy Using Sensor-Dependent Vibration Data for Blade Crack Identification in Centrifugal Booster Fans.

Science.gov (United States)

Chen, Jinglong; Sun, Hailiang; Wang, Shuai; He, Zhengjia

2016-05-09

Centrifugal booster fans are important equipment used to recover blast furnace gas (BFG) for generating electricity, but blade crack faults (BCFs) in centrifugal booster fans can lead to unscheduled breakdowns and potentially serious accidents, so in this work quantitative fault identification and an abnormal alarm strategy based on acquired historical sensor-dependent vibration data is proposed for implementing condition-based maintenance for this type of equipment. Firstly, three group dependent sensors are installed to acquire running condition data. Then a discrete spectrum interpolation method and short time Fourier transform (STFT) are applied to preliminarily identify the running data in the sensor-dependent vibration data. As a result a quantitative identification and abnormal alarm strategy based on compound indexes including the largest Lyapunov exponent and relative energy ratio at the second harmonic frequency component is proposed. Then for validation the proposed blade crack quantitative identification and abnormality alarm strategy is applied to analyze acquired experimental data for centrifugal booster fans and it has successfully identified incipient blade crack faults. In addition, the related mathematical modelling work is also introduced to investigate the effects of mistuning and cracks on the vibration features of centrifugal impellers and to explore effective techniques for crack detection.

Quantitative Index and Abnormal Alarm Strategy Using Sensor-Dependent Vibration Data for Blade Crack Identification in Centrifugal Booster Fans

Directory of Open Access Journals (Sweden)

Jinglong Chen

2016-05-01

Full Text Available Centrifugal booster fans are important equipment used to recover blast furnace gas (BFG for generating electricity, but blade crack faults (BCFs in centrifugal booster fans can lead to unscheduled breakdowns and potentially serious accidents, so in this work quantitative fault identification and an abnormal alarm strategy based on acquired historical sensor-dependent vibration data is proposed for implementing condition-based maintenance for this type of equipment. Firstly, three group dependent sensors are installed to acquire running condition data. Then a discrete spectrum interpolation method and short time Fourier transform (STFT are applied to preliminarily identify the running data in the sensor-dependent vibration data. As a result a quantitative identification and abnormal alarm strategy based on compound indexes including the largest Lyapunov exponent and relative energy ratio at the second harmonic frequency component is proposed. Then for validation the proposed blade crack quantitative identification and abnormality alarm strategy is applied to analyze acquired experimental data for centrifugal booster fans and it has successfully identified incipient blade crack faults. In addition, the related mathematical modelling work is also introduced to investigate the effects of mistuning and cracks on the vibration features of centrifugal impellers and to explore effective techniques for crack detection.

Design and A.C. loss considerations for the 60 mm dipole magnet in the High Energy Booster

International Nuclear Information System (INIS)

Snitchler, G.; Jayakumar, R.; Kovachev, V.; Orrell, D.

1991-01-01

The baseline design for the SSC High Energy Booster (HEB) has dipole bending magnets with a 50 mm aperture. A recent dynamic aperture study for the High Energy Booster (HEB) suggests that an increased aperture dipole magnet (DM) is desirable. Two cost neutral options for a 60 mm aperture HEBDM design are investigated. Field transfer function, field harmonics, and relative cost impact for these designs are presented. An analysis of the cryogenic heat load due to A.C. losses generated in the HEB ramp cycle are also reported. Included in this analysis are losses from superconductor hysteresis, yoke hysteresis, strand eddy currents, and cable eddy currents. The A.C. loss impact of 2.5 μm vs. 6 μm filament conductor is presented. Superconducting proximity effect is also considered for 2.5 μm filament conductors

CD4 T-helper cell cytokine phenotypes and antibody response following tetanus toxoid booster immunization

Science.gov (United States)

Routine methods for enumerating antigen-specific T-helper cells may not identify low-frequency phenotypes such as Th2 cells. We compared methods of evaluating such responses to identify tetanus toxoid- (TT) specific Th1, Th2, Th17 and IL10+ cells. Eight healthy subjects were given a TT booster vacci...

Model based controls and the AGS booster controls system architecture

International Nuclear Information System (INIS)

Casella, R.A.

1987-01-01

For the past three years the Accelerator Controls Section has been responsible for the development of the Heavy Ion Transfer Line (HITL) used to inject heavy ions created at the Tandem Van de Graaff into the Alternating Gradient Synchrotron (AGS). This was recognized as an opportunity to test new ideas for control of a beam line, which if successful, could be implemented in an upgrade of the existing control system for the AGS. The in place control system for the AGS consisted of DEC PDP10 computer as the primary computer interface to the accelerator via three control room consoles, and keeper of the device database. For the HITL project it was decided to make the control system a true distributed network putting more computing power down at the device level via intelligent subsystems. A network of Apollo workstations was added at the host level. Apollos run a distributed operating system and are connected to each other by the Domain Token Ring Network. The Apollos were seen as the new primary computers for consoles with each console containing at least one Apollo. These hosts and all other subsystems are connected to each other via an in house developed LAN (RELWAY). The design of the control system developed for HITL was mostly successful. The proposed AGS Booster is designed to be a synchrotron injector for the AGS. With the forthcoming development of the Booster for the AGS an opportunity has again developed to implement new ideas for accelerator control. One weakness of the HITL control system is the limited cpu power and poor debugging facilities of the stations

Making the Case for Reusable Booster Systems: The Operations Perspective

Science.gov (United States)

Zapata, Edgar

2012-01-01

Presentation to the Aeronautics Space Engineering Board National Research Council Reusable Booster System: Review and Assessment Committee. Addresses: the criteria and assumptions used in the formulation of current RBS plans; the methodologies used in the current cost estimates for RBS; the modeling methodology used to frame the business case for an RBS capability including: the data used in the analysis, the models' robustness if new data become available, and the impact of unclassified government data that was previously unavailable and which will be supplied by the USAF; the technical maturity of key elements critical to RBS implementation and the ability of current technology development plans to meet technical readiness milestones.

Online Measurement of the Energy Spread of Multi-Turn Beam in the Fermilab Booster at Injection

Energy Technology Data Exchange (ETDEWEB)

Nelson, J. [Brown U.; Bhat, C. M. [Fermilab; Hendricks, B. S. [Fermilab

2017-07-01

We have developed a computer program interfaced with the ACNET environment of Fermilab accelerators to measure energy spread of the proton beam from the LINAC at an injection into the Booster. It uses a digitizing oscilloscope and provides users an ability to configure the scope settings for optimal data acquisition from a resistive wall current monitor. When the program is launched, a) a one shot timeline is generated to initiate beam injection into the Booster, b) a gap of about 40 ns is produced in the injected beam using a set of fast kickers, c) collects line charge distribution data from the wall current monitor for the first 200 μs from the injection and d) performs complete data analysis to extract full beam energy spread of the beam. The program also gives the option to store the data for offline analyses. We illustrate a case with an example. We also present results on beam energy spread as a function of beam intensity from recent measurements.

Immune responses and safety after dart or booster vaccination of bison with Brucella abortus strain RB51

Science.gov (United States)

One alternative in the Bison remote vaccination environmental impact statement (EIS) for Yellowstone National Park includes inoculation of both calves and yearlings. Although RB51 vaccination of bison does protect against experimental challenge, it was unknown whether booster vaccination might enhan...

Immune responses of bison and efficacy after booster vaccination with Brucella abortus strain RB51

Science.gov (United States)

Thirty-one bison heifers were randomly assigned to saline (control; n=7) or single vaccination (n=24) with 1010 CFU of B. abortus strain RB51 (RB51). Some vaccinated bison were randomly selected for booster vaccination with 10**10 CFU of RB51 at 11 months after initial vaccination (n=16). When comp...

Internet Cognitive Behavioral Therapy for Women With Postnatal Depression: A Randomized Controlled Trial of MumMoodBooster.

Science.gov (United States)

Milgrom, Jeannette; Danaher, Brian G; Gemmill, Alan W; Holt, Charlene; Holt, Christopher J; Seeley, John R; Tyler, Milagra S; Ross, Jessica; Ericksen, Jennifer

2016-03-07

There are few published controlled trials examining the efficacy of Internet-based treatment for postnatal depression (PND) and none that assess diagnostic status (clinical remission) as the primary outcome. This is despite the need to improve treatment uptake and accessibility because fewer than 50% of postnatally depressed women seek help, even when identified as depressed. In a randomized controlled trial (RCT), we aimed to test the efficacy of a 6-session Internet intervention (the MumMoodBooster program, previously evaluated in a feasibility trial) in a sample of postnatal women with a clinical diagnosis of depression. The MumMoodBooster program is a cognitive behavioral therapy (CBT) intervention, is highly interactive, includes a partner website, and was supported by low-intensity telephone coaching. This was a parallel 2-group RCT (N=43) comparing the Internet CBT treatment (n=21) to treatment as usual (n=22). At baseline and at 12 weeks after enrollment, women's diagnostic status was assessed by telephone with the Standardized Clinical Interview for DSM-IV (SCID-IV) and symptom severity with the Beck Depression Inventory (BDI-II). Depression symptoms were measured repeatedly throughout the study period with the Patient Health Questionnaire (PHQ-9). At the end of the study, 79% (15/19) of women who received the Internet CBT treatment no longer met diagnostic criteria for depression on the SCID-IV (these outcome data were missing for 2 intervention participants). This contrasted with only 18% (4/22) remission in the treatment as usual condition. Depression scores on the BDI-II showed a large effect favoring the intervention group (d=.83, 95% CI 0.20-1.45). Small to medium effects were found on the PHQ-9 and on measures of anxiety and stress. Adherence to the program was very good with 86% (18/21) of users completing all sessions; satisfaction with the program was rated 3.1 out of 4 on average. Our results suggest that our Internet CBT program, MumMoodBooster

Investigation and Verification of the Aerodynamic Performance of a Fan/Booster with Through-flow Method

Science.gov (United States)

Liu, Xiaoheng; Jin, Donghai; Gui, Xingmin

2018-04-01

Through-flow method is still widely applied in the revolution of the design of a turbomachinery, which can provide not merely the performance characteristic but also the flow field. In this study, a program based on the through-flow method was proposed, which had been verified by many other numerical examples. So as to improve the accuracy of the calculation, abundant loss and deviation models dependent on the real geometry of engine were put into use, such as: viscous losses, overflow in gaps, leakage from a flow path through seals. By means of this program, the aerodynamic performance of a certain high through-flow commercial fan/booster was investigated. On account of the radial distributions of the relevant parameters, flow deterioration in this machine was speculated. To confirm this surmise, 3-D numerical simulation was carried out with the help of the NUMECA software. Through detailed analysis, the speculation above was demonstrated, which provide sufficient evidence for the conclusion that the through-flow method is an essential and effective method for the performance prediction of the fan/booster.

High-level immunogenicity is achieved vaccine with adjuvanted pandemic H1N1(2009) and improved with booster dosing in a randomized trial of HIV-infected adults.

Science.gov (United States)

Cooper, Curtis; Klein, Marina; Walmsley, Sharon; Haase, David; MacKinnon-Cameron, Donna; Marty, Kimberley; Li, Yan; Smith, Bruce; Halperin, Scott; Law, Barb; Scheifele, David

2012-01-01

More severe influenza disease and poor vaccine immunogenicity in HIV-infected patients necessitate improved immunization strategies to maximize vaccine efficacy. A phase III, randomized trial was conducted at 4 Canadian sites. Two dosing strategies (standard dose vs standard dose plus booster on day 21) were assessed in HIV patients aged 20 to 59 years during the H1N1(2009) pandemic. A single antigen, inactivated split adjuvanted (AS03(A)) influenza vaccine (Arepanrix) was utilized. Serum hemagglutination inhibition (HAI) titres were assessed at days 21 and 42 and at month 6. 150 participants received at least one injection. Baseline parameters were similar between groups: 83% male, 85% on HAART, median CD4 = 519 cells/mm(3), 84% with HIV RNA < 50 copies/mL. At day 21, seroprotection (HAI ≥1:40) was achieved in 80% (95% CI, 70-89) of participants. Seroconversion occurred in 74% (63-85). Seroprotection and seroconversion were further improved in those randomized to booster dosing: day 42, 94% (85-98) versus 73% (60-83) (P < .01) and 86% (75-93) versus 66% (5-77) (P = .01). Seroprotec-tion was retained in 40% (28-54) of recipients at month 6 with trends toward greater retention of immunity in booster recipients. High-level immunogenicity was achieved with a single dose of this adjuvanted vaccine. Immunogenicity was further improved with booster dosing. Use of this adjuvanted vaccine and booster represent an important approach to increasing immunogenicity in this vaccine hypo-responsive population.

Examining How Adding a Booster to a Behavioral Nutrition Intervention Prompts Parents to Pack More Vegetables and Whole Gains in Their Preschool Children's Sack Lunches.

Science.gov (United States)

Sweitzer, Sara J; Ranjit, Nalini; Calloway, Eric E; Hoelscher, Deanna M; Almansor, Fawaz; Briley, Margaret E; Roberts-Gray, Cynthia R

2016-01-01

Data from a five-week intervention to increase parents' packing of vegetables and whole grains in their preschool children's sack lunches showed that, although changes occurred, habit strength was weak. To determine the effects of adding a one-week booster three months post-intervention, children's (N = 59 intervention and 48 control) lunches were observed at baseline (week 0), post-intervention (week 6), pre-booster (week 20), and post-booster (week 26). Servings of vegetables and whole grains were evaluated in repeated measures models and results inspected relative to patterns projected from different explanatory models of behavior change processes. Observed changes aligned with projections from the simple associative model of behavior change. Attention in future studies should focus on behavioral intervention elements that leverage stimulus-response associations to increase gratification parents receive from providing their children with healthy lunches.

Design and A.C. loss considerations for the 60 mm dipole magnet in the high energy booster

International Nuclear Information System (INIS)

Snitchler, G.; Jayakumar, R.; Kovachev, V.; Orrell, D.

1991-04-01

The baseline design for the SSC High Energy Booster (HEB) has dipole bending magnets with a 50 mm aperture. A recent dynamic aperture study for the High Energy Booster (HEB) suggests that an increased aperture dipole magnet (DM) is desirable. Two cost neutral options for a 60 mm aperture HEBDM design are investigated. Field transfer function, field harmonics, and relative cost impact for these designs are presented. An analysis of the cryogenic heat and load due to A.C. losses generated in the HEB ramp cycle are also reported. Included in this analysis are losses from superconductor hysteresis, yoke hysteresis, strand eddy currents, and cable eddy currents. The A.C. loss impact of 2.5 μm vs. 6 μm filament conductor will be presented. Superconducting proximity effect is also considered for 2.5 μm filament conductors. 13 refs., 3 figs., 7 tabs

A Monte Carlo Analysis of the Thrust Imbalance for the RSRMV Booster During Both the Ignition Transient and Steady State Operation

Science.gov (United States)

Foster, Winfred A., Jr.; Crowder, Winston; Steadman, Todd E.

2014-01-01

This paper presents the results of statistical analyses performed to predict the thrust imbalance between two solid rocket motor boosters to be used on the Space Launch System (SLS) vehicle. Two legacy internal ballistics codes developed for the Space Shuttle program were coupled with a Monte Carlo analysis code to determine a thrust imbalance envelope for the SLS vehicle based on the performance of 1000 motor pairs. Thirty three variables which could impact the performance of the motors during the ignition transient and thirty eight variables which could impact the performance of the motors during steady state operation of the motor were identified and treated as statistical variables for the analyses. The effects of motor to motor variation as well as variations between motors of a single pair were included in the analyses. The statistical variations of the variables were defined based on data provided by NASA's Marshall Space Flight Center for the upgraded five segment booster and from the Space Shuttle booster when appropriate. The results obtained for the statistical envelope are compared with the design specification thrust imbalance limits for the SLS launch vehicle

COMMISSIONING RESULTS OF SLOW EXTRACTION OF HEAVY IONS from THE AGS BOOSTER

International Nuclear Information System (INIS)

BROWN, K.A.; AHRENS, L.; BELLAVIA, S.; BINELLO, S.; BRELSFORD, B.; DUMONT, D.; ENG, W.; GARDNER, C.; GASSNER, D.; GLENN, J.W.; HAMMONS, L.; HOCK, J.; HOFF, L.; HUTCHINSON, E.; JAMILKOWSKI, J.; KLING, N.; KOTLYAR, Y.; KRISHOCK, A.; LOCKEY, R.; MAPES, M.; MARNERIS, I.; MARR, G.; MCNERNEY, A.; MEYER, A.; MORRIS, J.; NAYLOR, C.; NEMESURE, S.; PHILLIPS, D.; RUSEK, A.; RYAN, J.; SHREY, T.; SNYDSTRUP, L.; TSOUPAS, N.; VANKUIK, B.; ZAHARIOU-COHEN, K.; ZENO, K.

2003-01-01

Brookhaven's AGS Booster has been modified to deliver slow extracted beam to a new beam line, the NASA Space Radiation Laboratory (NSRL). This facility was constructed in collaboration with NASA for the purpose of performing radiation effect studies for the NASA space program. The design of the resonant extraction system has been described in [1]. A more detailed description, which includes predictions of the slow extracted beam time structure has been described in [2]. In this report we will present results of the system commissioning and performance

Antifouling paint particles: Sources, occurrence, composition and dynamics.

Science.gov (United States)

Soroldoni, Sanye; Castro, Ítalo Braga; Abreu, Fiamma; Duarte, Fabio Andrei; Choueri, Rodrigo Brasil; Möller, Osmar Olinto; Fillmann, Gilberto; Pinho, Grasiela Lopes Leães

2018-06-15

Sources, occurrence, composition and dynamics of antifouling paint particles (APPs) were assessed in Patos Lagoon estuary (PLE), Southern Brazil. Ten areas including boatyards, a marina and artisanal fishing harbors were identified in the estuarine system as potential sources of APPs. The APPs generated in these areas were highly heterogeneous considering the size, shape and composition. Based on an estimate of antifouling paint usage and amount of boats in each studied area, artisanal fishing harbors could be the main source of particles to PLE. However, relatively high amounts of APPs, which ranged from 130 to 40,300 μg g -1 , were detected in sediments collected in front of boatyards and a marina. The uneven distribution of APPs levels among the sediment samples were probably due to the presence of diffuse sources (fishing harbors) associated to "hotspots" (boatyards and marina) along the study area. Additionally, data of settling experiment indicate that size, shape and density of APPs, combined to local hydrodynamics, appears to contribute to the mobility of these residues within the estuary. In the main channel of PLE, smaller particles tend to be transported to adjacent coastal zone while particles tend to be deposited in the sediment surface of sheltered areas. Since different trace metals, and booster biocides were detected in APPs that were not correctly disposed, these particles can be considered as an important source of contamination to aquatic environments. The present data suggest that APPs represent an environmental problem for aquatic systems in Brazil, since the country lacks legislation in addition to inefficient control mechanisms. An improvement in boat maintenance processes are urgently needed to avoid this continuous release of APPs into the aquatic systems. Copyright © 2018 Elsevier Ltd. All rights reserved.

Status of rf development work on a ferrite tuned amplifier cavity for the TRIUMF KAON factory booster ring

International Nuclear Information System (INIS)

Poirier, R.L.; Enegren, T.

1987-01-01

Of the five synchrotron rings in the proposed TRIUMF KAON factory, the Booster ring to accelerate the proton beam from 440 MeV to 3 GeV has the most demanding rf requirements, primarily because of the relatively large frequency swing of 46.1 MHz to 61.1 MHz at a high repetition rate of 50 Hz. In the current reference design, the Booster lattice has twelve 3.9 m drift spaces with 2.5 m in each drift space available for installation of rf cavities to provide a required effective acceleration voltage of up to 600 kV per turn i.e. 50 kV per cavity. Design and development studies of a suitable cavity-amplifier system are in progress. For the initial reference design a system based on the one used in the Fermilab booster synchrotron has been chosen. That is, a double-gap drift-tube cavity with parallel-biased ferrite tuners and excited with a directly coupled Eimac Y567B tetrode. To meet the tuning and voltage requirements within the various mechanical and other constraints such as tube-to-gap voltage ratio, ferrite power density and available space, the reference design had to be further modified and a cold model of the cavity and tuners was constructed from copper-covered cardboard cylinders. From the results of the cold model measurements a new reference design was established and design work has begun on a full power prototype of the cavity-amplifier system

Anti-HBs in immunized children with cuban hepatitis B vaccine and impact of booster dose after five years

International Nuclear Information System (INIS)

Dahifar, H.; Mousavi, F.; Ghorbani, A.

2008-01-01

Hepatitis B virus infection and associated diseases are a major public health problem. This study was planned to find out the persistence of antibody against hepatitis B surface antigen in Iranian vaccinated children after five years. Anti-HBs titers in a group of healthy good - responder children who were vaccinated with Cuban hepatitis B vaccine in infancy were measured after five years. Children with antibody titers <100 mlU/ml were revaccinated and retested after four weeks. Mean anti-HBs titers in 68 children (29 females, 39 males) were 482.1 mlU/ml at six months after the third dose of primary vaccination and 153 mlU/ml at five years later. Total mean anti-HBs titers in 36 (52.9%) children out of 68 (17 females, 19 males) were 38.3 mlU/ml and 4(5.8%) of 68 children (two of each sexes) had no detectable antibody after five years. Total mean anti-HBs titers in these hypo- responder and non- responder were 774.3 mlU/ml and 625.5 mlU/ml respectively after booster dose. In a group of children, who were immunized with Cuban hepatitis B vaccine from birth, anti-HBS titers fell at 6.5 years of age and almost half of children became hypo responder or no responder and their anti-HBs titers developed secondary rise after booster vaccination. All children showed immunologic memory to a booster dose. (author)

Bench measurements of coupling impedance of AGS Booster components

International Nuclear Information System (INIS)

Ratti, A.; Shea, T.J.

1991-01-01

Quantifying instability thresholds for modern synchrotrons and storage rings requires some knowledge of the accelerator's coupling impedance. To this end, the wire technique has been implemented to measure the longitudinal coupling impedance of AGS Booster devices. The techniques are being refined to allow measurement of RHIC devices at higher frequencies. All the measurements are performed using an HP 8753 Network Analyzer controlled via GPIB by a Macintosh computer. The computer provides an environment for automated data acquisition, data analysis, and report generation. Resistive matches between the 50ω analyzer cables and the 300ω pipe-and-wire structure allow the use of a simple response calibration in the measurement of S21 to 400MHz. Results from ferrite loaded rf cavities, position monitors and kickers are presented. 4 refs., 4 figs

The new frontier in muscular dystrophy research: booster genes

DEFF Research Database (Denmark)

Engvall, Eva; Wewer, Ulla M

2003-01-01

More than 30 different forms of muscular dystrophy (MD) have been molecularly characterized and can be diagnosed, but progress toward treatment has been slow. Gene replacement therapy has met with great difficulty because of the large size of the defective genes and because of difficulties...... of the boosters are better understood, drugs may be developed to provide the boost to muscle. Some of the experiences in models of muscular dystrophy may inspire new approaches in other genetic degenerative diseases as well....... in delivering a gene to all muscle groups. Cell replacement therapy has also been difficult to realize. Will it even be possible to design specific therapy protocols for all MDs? Or is a more realistic goal to treat some of the secondary manifestations that are common to several forms of MD, such as membrane...

Persistence of bactericidal antibodies following early infant vaccination with a serogroup B meningococcal vaccine and immunogenicity of a preschool booster dose.

Science.gov (United States)

Snape, Matthew D; Saroey, Praveen; John, Tessa M; Robinson, Hannah; Kelly, Sarah; Gossger, Nicoletta; Yu, Ly-Mee; Wang, Huajun; Toneatto, Daniela; Dull, Peter M; Pollard, Andrew J

2013-10-15

The multicomponent serogroup B meningococcal (4CMenB) vaccine was recently licensed for use in Europe. There are currently no data on the persistence of bactericidal antibodies induced by use of this vaccine in infants. Our objective was to evaluate serogroup B-specific bactericidal antibodies in children aged 40-44 months previously vaccinated at 2, 4, 6 and 12 months of age. Participants given 4 doses of 4CMenB as infants received a fifth dose of the vaccine at 40-44 months of age. Age-matched participants who were MenB vaccine-naive received 4CMenB and formed the control group. We evaluated human complement serum bactericidal activity (hSBA) titres at baseline and 1 month after each dose of 4CMenB. Before a booster dose at enrolment, 41%-76% of 17 participants previously vaccinated with 4CMenB in infancy had hSBA titres of 4 or greater against 4 reference strains. Before vaccination in the control group (n = 40) these proportions were similar for strains 44/76-SL (63%) and M10713 (68%) but low for strains NZ98/254 (0%) and 5/99 (3%). A booster dose in the 4CMenB-primed participants generated greater increases in hSBA titres than in controls. As has been observed with other meningococcal vaccines, bactericidal antibodies waned after vaccination with 4CMenB administered according to an approved infant vaccination schedule of 2, 4, 6 and 12 months of age, but there was an anamnestic response to a booster dose at 40-44 months of age. If 4CMenB were introduced into routine vaccination schedules, assessment of the need for a booster dose would require data on the impact of these declining titres on vaccine effectiveness. ClinicalTrials.gov, no. NCT01027351.

A fully liquid DTaP-IPV-Hep B-PRP-T hexavalent vaccine for primary and booster vaccination of healthy Mexican children.

Science.gov (United States)

Aquino, Amalia Guadalupe Becerra; Brito, Maricruz Gutiérrez; Doniz, Carlos E Aranza; Herrera, Juan Francisco Galán; Macias, Mercedes; Zambrano, Betzana; Plennevaux, Eric; Santos-Lima, Eduardo

2012-10-05

To evaluate an investigational, fully liquid hexavalent diphtheria-tetanus-acellular pertussis-inactivated poliovirus-hepatitis B-Haemophilus influenzae type b (DTaP-IPV-Hep B-PRP-T: Hexaxim™) vaccine for primary and booster vaccination of healthy children in Mexico. Infants (N=1189) were randomized to receive one of three lots of the DTaP-IPV-Hep B-PRP-T vaccine or a licensed hexavalent control vaccine (Infanrix™ hexa) for primary vaccination at 2, 4 and 6 months. All participants who completed the primary series and agreed to participate in the booster part of the study received a dose of the investigational vaccine at 15-18 months of age. Validated serological assays and parental reports were used to assess immunogenicity and safety, respectively. Post-primary vaccination, ≥95.8% of participants in both the DTaP-IPV-Hep B-PRP-T and control groups were seroprotected (SP) against diphtheria, tetanus, poliovirus, hepatitis B and PRP, or had seroconverted (SC) to the pertussis toxin (PT) and filamentous hemagglutinin (FHA) pertussis antigens. The SP/SC rates induced by the three DTaP-IPV-Hep B-PRP-T lots were equivalent. No differences in SP/SC rates were observed between the pooled lots of investigational vaccine and the control vaccine. Antibody persistence at 15-18 months was comparable between groups, with strong increases in all antibody concentrations post-DTaP-IPV-Hep B-PRP-T booster. Both vaccines were well tolerated for primary vaccination, as was the booster dose of DTaP-IPV-Hep B-PRP-T. These study findings confirm the suitability of the combined, fully liquid DTaP-IPV-Hep B-PRP-T vaccine for inclusion in routine childhood vaccination schedules. Copyright © 2012 Elsevier Ltd. All rights reserved.

Environmentally friendly procedure based on VA-MSPD for the determination of booster biocides in fish tissue.

Science.gov (United States)

Vieira, Augusto A; Caldas, Sergiane S; Escarrone, Ana Laura Venquiaruti; Arias, Jean Lucas de Oliveira; Primel, Ednei Gilberto

2018-03-01

Booster biocides have been widely applied to ships and other submerged structures. These compounds can be released into the marine environment as the result of vessel hull leaching and may remain in different environmental compartments. This study aimed at introducing an environmentally friendly procedure for the extraction of irgarol and diuron from fish samples by vortex-assisted matrix solid phase dispersion (VA-MSPD) with detection by liquid chromatography tandem mass spectrometry. Different types of solid supports and solvents were evaluated. The best results were found when 0.5g mussel shell, 0.5g sodium sulfate and 5mL ethanol were used. Analytical recoveries ranged from 81 to 110%, with RSD below 10%, whereas the matrix effect was between -17 and 1% (for all samples under study). LOQ values of irgarol and diuron were 5 and 50ngg -1 , respectively. The method under investigation proved to be a promising alternative to controlling contamination of fish by booster biocides, with low consumption of biodegradable reagents. Copyright © 2017 Elsevier Ltd. All rights reserved.

Evaluation of the criticality constant from Pulsed Neutron Source measurements in the Yalina-Booster subcritical assembly

International Nuclear Information System (INIS)

Bécares, V.; Villamarín, D.; Fernández-Ordóñez, M.; González-Romero, E.M.; Berglöf, C.; Bournos, V.; Fokov, Y.; Mazanik, S.; Serafimovich, I.

2013-01-01

Highlights: ► New methodology proposed to determine the reactivity of subcritical systems. ► Methodology tested in PNS experiments at the Yalina-Booster subcritical assembly. ► The area-ratio and the prompt decay constant methods have been used for validation. ► The absolute reactivity of the system is determined in spite of large spatial effects. - Abstract: The prompt decay constant method and the area-ratio (Sjöstrand) method constitute the reference techniques for measuring the reactivity of a subcritical system using Pulsed Neutron Source experiments (PNS). However, different experiments have shown that in many cases it is necessary to apply corrections to the experimental results in order to take into account spectral and spatial effects. In these cases, the approach usually followed is to develop different specific correction procedures for each method. In this work we discuss the validity of prompt decay constant method and the area-ratio method in the Yalina-Booster subcritical assembly and propose a general correction procedure based on Monte Carlo simulations

A fully liquid DTaP-IPV-HB-PRP-T hexavalent vaccine for primary and booster vaccination of healthy Turkish infants and toddlers

Science.gov (United States)

Ceyhan, Mehmet; Yıldırım, İnci; Tezer, Hasan; Devrim, İlker; Feroldi, Emmanuel

2017-08-23

Background/aim: Immunogenicity and safety of a primary series of a fully liquid, hexavalent DTaP-IPV-HB-PRP-T vaccine given at 2, 3, and 4 months of age compared to licensed comparators and a DTaP-IPV-HB-PRP-T booster at 15?18 months were evaluated. Materials and methods: This was a Phase III, randomized, open-label trial. Primary series (no hepatitis B [HB] at birth) of DTaP-IPV-HB-PRP-T (N = 155) (group 1) or licensed control vaccines (DTaP-IPV//PRP-T and standalone HB: N = 155) (group 2) and DTaP-IPV-HB-PRP-T booster were administered. Noninferiority was evaluated 1 month postprimary series for anti-HB seroprotection (SP). All other analyses were descriptive. Safety was assessed from parental reports. Results: Postprimary series noninferiority of anti-HB ≥ 10 mIU/mL was demonstrated for the DTaP-IPV-HB-PRP-T vaccine (94.0%) compared to the licensed control (96.1%). Postprimary series primary SP and seroconversion (SC) rates were high and similar for both groups. Antibody persistence (prebooster) was high for each antigen and similar between groups except for HB, which was lower for DTaP-IPV-HB-PRP-T than for standalone HB. For each antigen except HB, DTaP-IPV-HB-PRP-T booster responses were high and similar in each group. Safety was good for primary and booster series and similar between groups. Conclusion: The DTaP-IPV-HB-PRP-T vaccine is immunogenic and safe when administered in a challenging primary series schedule without HB vaccination at birth.

Development Of Solid Phase Radioimmunoassay Using Antibody Coupled Cellulose Particles For Measurement Of Prolactin In Human Serum

International Nuclear Information System (INIS)

Abdel-Ghany, I.Y.

2013-01-01

The objective of the present study was to prepare solid phase radioimmunoassay (RIA) reagents. Development as well as optimization and validation of RIA system using solid phase cellulose particles for the measurement of prolactin (PRL) in human serum were described. The production of polyclonal antibodies was carried out by immunizing three Balb/C mice intraperitoneal through primary injection and two booster doses. The activation of cellulose particles using 1,1-carbonyl diimidazole (CDI) and coupling of these solid phase particles with IgG fraction of mouse anti-PRL were carried out. Preparation of 125 I-PRL tracer was prepared using lactoperoxidase method then purified by gel filtration using sephadex G-100. The PRL standards were prepared using a highly purified PRL antigen with assay buffer as standard matrix. Optimization and validation of the assay were carried out. The results obtained provide a low cost, simple, sensitive, specific and accurate RIA system of prolactin based on solid phase separation. These cellulose particles retain their characteristics during storage for 6 months at 4 degree C. In conclusion, this assay could be used as a useful diagnostic tool for pituitary dysfunctions and possible reproductive disability

Thermodynamic analysis of transcritical CO2 booster refrigeration systems in supermarket

International Nuclear Information System (INIS)

Ge, Y.T.; Tassou, S.A.

2011-01-01

Research highlights: → The CO 2 booster systems are widely applied in supermarket refrigeration. → Control optimisation can improve the performance of the CO 2 refrigeration systems. → The effects of some important parameters on the system performance are examined. → The optimal high-side pressure in the transcritical cycles is established and derived. -- Abstract: Due to less environmental impact, the CO 2 booster refrigeration system has been widely applied in the modern supermarket as a substitute for the conventional R404A multiplex system. However, the performance efficiency of the CO 2 system still requires further improvement in order to save energy; thus, one of the most efficient techniques would be to investigate and employ the optimal controls for refrigerant high side pressures at various operating states. In this paper, the possible parameters affecting system efficiency of the CO 2 system in the transcritical cycle at a higher ambient air temperature are identified through thermodynamic analysis, but cannot be quantified mathematically because of the high non-linearity involved. Instead, sensitive analysis of the system by means of the thermodynamic model is used to examine the effects of parameters including high side refrigerant pressure, ambient air temperature, refrigerant intermediate pressure, and medium and low evaporating temperatures, superheating, effectiveness of suction line heat exchanger, and compressor efficiency on system performance. Consequently, the optimal high side pressure in the transcritical cycle is established and derived as a function of three important parameters consisting of ambient air temperature, the effectiveness of suction line heat exchanger and compressor efficiency. In addition, optimal operating parameters such as the intermediate pressure are also proposed to improve the system performance.

Immunogenicity and Reactogenicity of DTPa-IPV/Hib Vaccine Co-administered With Hepatitis B Vaccine for Primary and Booster Vaccination of Taiwanese Infants

Directory of Open Access Journals (Sweden)

Pei-Lan Shao

2011-06-01

Full Text Available Immunogenicity and reactogenicity of the combined diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae type b (Hib conjugate vaccine (DTPa-IPV/Hib, Infanrix™-IPV + Hib was assessed when co-administered with hepatitis B (HBV vaccine. Seventy healthy infants received DTPa-IPV/Hib at 1.5, 3.5, 6 and 15–18 months, and HBV at birth, 1.5, 6 and 15–18 months of age. Serological responses were assessed. Diphtheria, tetanus, Hib and pertussis seroprotection/seropositivity rates were 100% after primary vaccination. Post-primary immune responses to poliovirus could not be evaluated for technical reasons. However, after the booster dose, seroprotection/seropositivity rates, including poliovirus, were 100%. Over 95% were seroprotected against HBV. Post-booster geometric mean antibody concentrations/titers (GMC/GMTs rose from 14-fold to 45-fold, indicating effective priming against all antigens, including polioviruses. DTPa-IPV/Hib was well tolerated alone or co-administered with HBV. No serious adverse events were considered related to vaccination. Primary and booster vaccination with combined DTPa-IPV/Hib and HBV was immunogenic and well tolerated. Combination vaccines enable vaccine providers to conveniently provide routine pediatric immunizations, with minimal discomfort.

[EIA-IgG antibody measles prevention level estimated from measles neutralizing, particle agglutination and hemagglutination-inhibition antibody titer].

Science.gov (United States)

Takayama, Naohide; Saika, Shizuko; Ichinohe, Sadato

2009-09-01

Measles hemagglutination inhibition (HI) antibody titer, widely used in clinical practice to simply and easily determine the measles immunity level has, in recent years, been increasingly replaced by measles IgG-antibody titer determined by enzyme-immunoassay (EIA). HI antibody titer appears to reflect this protective level, because HI measures the antibody against H protein required for the measles virus to adhere to host cells. EIA-IgG antibody titer does not correlate with the protective level, similar to particle agglutination (PA) titer, because EIA measures different antibodies, including those unrelated to measles protection. After determining HI, PA, neutralizing test (NT) results, and EIA-IgG antibody titer for individual specimens, we compared EIA-IgG antibody titer obtained using an EIA-Kit (Denka Seiken) to HI, PA, and NT titer with the following results: (1) Subjects with EIA-IgG titer of > or = 12.0 may be protected against measles: (2) Subjects with EIA-IgG titer of 4.0 to 8.0 appear to be protected insufficiently requiring a booster dose against measles: (3) Subjects with EIA-IgG titer of 8.0 to 12.0 may benefit from booster vaccination.

Solid Phase Radioimmunoassay for Measuring Serum Prolactin Using Antibody Coupled Magnetizable Particles

International Nuclear Information System (INIS)

El-Bayoumy, A.S.A.

2012-01-01

The objective of the present work was to prepare solid phase radioimmunoassay (RIA) reagents. Development as well as optimization and validation of RIA system using solid phase magnetic particles for the measurement of prolactin (PRL) in human serum are described. The production of polyclonal antibodies was carried out by immunizing three Balb/C mice intraperitoneal through primary injection and two booster doses. Low density magnetizable cellulose iron oxide particles have been used to couple covalently to the IgG fraction of polyclonal anti-prolactin using carbonyl diimidazole activation method and applied as a solid phase separating agent for RIA of serum prolactin. Preparation of 125 I-PRL tracer was prepared using lactoperoxidase method and it was purified by gel filtration using sephadex G-100. The PRL standards were prepared using a highly purified PRL antigen with assay buffer as standard matrix. Optimization and validation of the assay were carried out. The results obtained provide a low cost, simple, sensitive, specific and accurate RIA system of prolactin based on magnetizable solid phase separation. These magnetic particles retain their characteristics during storage for 6 months at 4 degree C. In conclusion, this assay could be used as a useful diagnostic tool for pituitary dysfunction and possible reproductive disability.

Digital intelligent booster for DCC miniature train networks

Science.gov (United States)

Ursu, M. P.; Condruz, D. A.

2017-08-01

Modern miniature trains are now driven by means of the DCC (Digital Command and Control) system, which allows the human operator or a personal computer to launch commands to each individual train or even to control different features of the same train. The digital command station encodes these commands and sends them to the trains by means of electrical pulses via the rails of the railway network. Due to the development of the miniature railway network, it may happen that the power requirement of the increasing number of digital locomotives, carriages and accessories exceeds the nominal output power of the digital command station. This digital intelligent booster relieves the digital command station from powering the entire railway network all by itself, and it automatically handles the multiple powered sections of the network. This electronic device is also able to detect and process short-circuits and overload conditions, without the intervention of the digital command station.

Long-term persistence in protection and response to a hepatitis B vaccine booster among adolescents immunized in infancy in the western region of China.

Science.gov (United States)

Wang, Zhen-Zi; Gao, Yu-Hua; Lu, Wei; Jin, Cun-Duo; Zeng, Ying; Yan, Ling; Ding, Feng; Li, Tong; Liu, Xue-En; Zhuang, Hui

2017-04-03

To evaluate the persistence of protection from hepatitis B (HB) vaccination among adolescents immunized with a primary series of HB vaccine as infants, and the immune response to booster doses. Healthy adolescents aged 15-17 y vaccinated with HB vaccine only at birth were enrolled. Baseline serum hepatitis B surface antigen (HBsAg), antibody against hepatitis B surface antigen (anti-HBs) and antibody against hepatitis B core antigen (anti-HBc) were detected by Enzyme-Linked Immunosorbent Assay (ELISA) and anti-HBs level was measured using Chemiluminescent Microparticle Immunoassay (CMIA). The rate of HBV infection was calculated. The seroprotection rate of anti-HBs (≥ 10 mIU/ml) and GMC level were used to evaluate the persistence of immunity from HB vaccination. Those with anti-HBs infants, 3 (1.7%) had HBV infection and 74 (41.1%) had anti-HBs ≥ 10 mIU/ml with a GMC of 145.11 mIU/ml. The remaining 103 (57.2%) with anti-HBs < 10 mIU/ml received a booster dose of 20 μg HB vaccine and achieved the seroprotection rate of 84% (84/100) and a GMC of 875.19 mIU/ml at one month post-booster. An additional dose of 60 μg HB vaccine was administered to the 16 adolescents with anti-HBs < 10 mIU/ml after the first booster. All of them obtained anti-HBs seroprotection with a GMC of 271.02 mIU/ml at 1.5 months after an additional dose. Vaccine-induced immunity persisted for up to 15-17 y in 89.3% (158/177) of participants after a primary HB vaccination in infancy. Administering a booster dose of 20μg HB vaccine elicited an anamnestic immune responses in the majority of individuals with baseline anti-HBs <10 mIU/ml.

Automated design and optimization of flexible booster autopilots via linear programming. Volume 2: User's manual

Science.gov (United States)

Hauser, F. D.; Szollosi, G. D.; Lakin, W. S.

1972-01-01

COEBRA, the Computerized Optimization of Elastic Booster Autopilots, is an autopilot design program. The bulk of the design criteria is presented in the form of minimum allowed gain/phase stability margins. COEBRA has two optimization phases: (1) a phase to maximize stability margins; and (2) a phase to optimize structural bending moment load relief capability in the presence of minimum requirements on gain/phase stability margins.

Hepatitis A vaccine. A new convenient single-dose schedule with booster when long-term immunization is warranted

DEFF Research Database (Denmark)

Victor, J; Knudsen, J D; Nielsen, L P

1994-01-01

A total of 162 anti-HAV-negative healthy adults were immunized with a single high dose (1440 ELISA units = 1 ml) of inactivated hepatitis A vaccine and a booster was given at month 6. Antibodies were measured after modification of a commercial ELISA kit, enabling quantification of titres down to 6...

Rf beam loading in the Brookhaven AGS with booster injection

International Nuclear Information System (INIS)

Zhang, S.Y.; Raka, E.; Weng, W.T.

1992-01-01

Multi-batch bunched beam loading during injection from the Booster to the AGS will be discussed. The full intensity beam injection to the upgraded AGS rf system with beam phase and radial feedbacks will be studied. It is shown that a beam phase feedback is necessary in order to guarantee a predictable hewn behavior after the first batch injection, otherwise the initial phase deviation for the following batch injections cannot be controlled. However, the effectiveness of the phase feedback control of the transient beam loading may be limited by an emittance blow up in the process. It is shown that a fast power amplifier feedback with a moderate gain can significantly reduce the transient effect of the bunched beam injection

Immunogenicity and safety of a booster dose of the 13-valent pneumococcal conjugate vaccine in children primed with the 10-valent or 13-valent pneumococcal conjugate vaccine in the Czech Republic and Slovakia.

Science.gov (United States)

Urbancikova, Ingrid; Prymula, Roman; Goldblatt, David; Roalfe, Lucy; Prymulova, Karolina; Kosina, Pavel

2017-09-12

Although both the 13-valent pneumococcal conjugate vaccine (PCV13) and the 10-valent pneumococcal non-typeable Haemophilus influenzae protein D-conjugate vaccine (PHiD-CV) are widely used, it is unclear how interchangeable they are in terms of immunogenicity. Two phase 3, open-label, multicenter studies were conducted to assess the immunogenicity and safety of a booster dose of PCV13 in children primed with PHiD-CV or PCV13. In the Czech Republic, 12-15-month-old children received a PCV13 booster after 3-dose priming with either PHiD-CV or PCV13. In Slovakia, 11-12-month-old children received PCV13 following 2-dose priming with either PHiD-CV or PCV13. Serum IgG concentrations were assessed by enzyme-linked immunosorbent assay and functional antibodies were assessed by opsonophagocytic assay (OPA) before the booster and at 1 and 12months afterward. The primary objective of these studies was to assess non-inferiority of OPA titers for serotype 19A in PHiD-CV-primed subjects compared to those in PCV13-primed children 1month post-booster. A total of 98 subjects in the Czech Republic and 89 subjects in Slovakia were included. One month after the PCV13 booster dose, the IgG and OPA immune responses to serotype 19A in subjects primed with 2 or 3 doses of PHiD-CV were non-inferior to those in subjects primed with PCV13. Non-inferior and persistent immune responses to most other vaccine serotypes were also observed after the PCV13 booster in PHiD-CV-primed subjects. No safety issues were raised in either study. Overall, robust IgG and OPA immunological responses were observed after booster vaccination with PCV13 in children primed with 2 or 3 doses of PHiD-CV or PCV13, including for serotypes not included in PHiD-CV. These results suggest that these vaccines are interchangeable in terms of safety and immunogenicity and that PCV13 can be used as a booster in the context of mixed schedules. (EudraCT numbers: 2012-005366-35 and 2012-005367-27). Copyright © 2017 Elsevier Ltd

Effects of two physiotherapy booster sessions on outcomes with home exercise in people with knee osteoarthritis: a randomized controlled trial.

Science.gov (United States)

Bennell, Kim L; Kyriakides, Mary; Hodges, Paul W; Hinman, Rana S

2014-11-01

Enhancing exercise adherence over the longer term is an important goal in self-management of knee osteoarthritis (OA). Following an initial period of more intensive exercise supervision, this study investigated whether 2 additional physiotherapy visits improved outcomes with continued home exercise over a subsequent 24-week period. A total of 78 people with medial knee OA (mean ± SD age 62.1 ± 6.9 years, mean ± SD body mass index 29.4 ± 4.0 kg/m(2) , and radiographic disease severity 19% mild, 49% moderate, and 32% severe) who completed a 12-week physiotherapist-supervised exercise trial were randomly allocated to 2 30-minute physiotherapy booster sessions (delivered by 8 physiotherapists in private clinics) or no booster sessions for the subsequent 24 weeks. All participants were asked to continue home exercises 4 times weekly. Primary outcomes were change in pain, using a 100-mm visual analog scale, and self-reported physical function, measured using the Western Ontario McMaster Universities Osteoarthritis Index. Participants and physiotherapists were unblinded to group allocation, although participants were blinded to the study hypothesis. A total of 74 participants (95%) completed the trial. There was no significant difference between groups for change in pain (mean difference [95% confidence interval (95% CI)] 0.7 mm [-9.4, 8.0]; P = 0.88) or physical function (-0.3 units [95% CI -4.0, 3.5]; P = 0.88). The mean ± SD percentage of home exercise sessions completed was 56% ± 34% in the booster group and 51% ± 37% in the control group (P > 0.05). Two booster sessions with a physiotherapist did not influence pain or physical function outcomes, or measures of home exercise adherence. These findings suggest other more effective strategies are needed to maximize longer-term adherence with the aim to achieve greater improvements in clinical outcomes from exercise in this patient population. Copyright © 2014 by the American College of Rheumatology.

Optimal scheduling for electric heat booster under day-ahead electricity and heat pricing

DEFF Research Database (Denmark)

Cai, Hanmin; You, Shi; Bindner, Henrik W.

2017-01-01

Multi-energy system (MES) operation calls for active management of flexible resources across energy sectors to improve efficiency and meet challenging environmental targets. Electric heat booster, a solution for Domestic Hot Water (DHW) preparation under Low-Temperature-District-Heating (LTDH......) context, is identified as one of aforementioned flexible resources for electricity and heat sectors. This paper extends the concept of optimal load scheduling under day-ahead pricing from electricity sector only to both electricity and heat sectors. A case study constructing day-ahead energy prices...

Doubling Beam Intensity Unlocks Rare Opportunities for Discovery at Fermi National Accelerator Laboratory

International Nuclear Information System (INIS)

Segui, Jennifer A.

2014-01-01

Particle accelerators such as the Booster synchrotron at the Fermi National Accelerator Laboratory (FNAL) produce high-intensity proton beams for particle physics experiments that can ultimately reveal the secrets of the universe. High-intensity proton beams are required by experiments at the ''intensity frontier'' of particle physics research, where the availability of more particles improves the chances of observing extremely rare physical processes. In addition to their central role in particle physics experiments, particle accelerators have found widespread use in industrial, nuclear, environmental, and medical applications. RF cavities are essential components of particle accelerators that, depending on the design, can perform multiple functions, including bunching, focusing, decelerating, and accelerating a beam of charged particles. Engineers are working to model the RF cavities required for upgrading the 40-year old Booster synchrotron. It is a rather complicated process to refurbish, test, and qualify the upgraded RF cavities to sustain an increased repetition rate of the RF field required to produce proton beams at double the current intensity. Both multiphysics simulation and physical measurements are used to evaluate the RF, thermal, and mechanical properties of the Booster RF cavities.

Simulation of space charge effects and transition crossing in the Fermilab Booster

International Nuclear Information System (INIS)

Lucas, P.; MacLachlan, J.

1987-03-01

The longitudinal phase space program ESME, modified for space charge and wall impedance effects, has been used to simulate transition crossing in the Fermilab Booster. The simulations yield results in reasonable quantitative agreement with measured parameters. They further indicate that a transition jump scheme currently under construction will significantly reduce emittance growth, while attempts to alter machine impedance are less obviously beneficial. In addition to presenting results, this paper points out a serious difficulty, related to statistical fluctuations, in the space charge calculation. False indications of emittance growth can appear if care is not taken to minimize this problem

TOPOLOGY FOR A DSP BASED BEAM CONTROL SYSTEM IN THE AGS BOOSTER

International Nuclear Information System (INIS)

DELONG, J.; BRENNAN, J.M.; HAYES, T.; LE, T.N.; SMITH, K.

2003-01-01

The AGS Booster supports beams of ions and protons with a wide range of energies on a pulse-by-pulse modulation basis. This requires an agile beam control system highly integrated with its controls. To implement this system digital techniques in the form of Digital Signal Processors, Direct Digital Synthesizers, digital receivers and high speed Analog to Digital Converters are used. Signals from the beam and cavity pick-ups, as well as measurements of magnetic field strength in the ring dipoles are processed in real time. To facilitate this a multi-processor topology with high bandwidth data links is being designed

Technical assessment of electric heat boosters in low-temperature district heating based on combined heat and power analysis

DEFF Research Database (Denmark)

Cai, Hanmin; You, Shi; Wang, Jiawei

2018-01-01

This paper provides a technical assessment of electric heat boosters (EHBs) in low-energy districts. The analysis is based on a hypothetical district with 23 terraced single-family houses supplied by both a lowtemperature district heating (LTDH) network and a low-voltage network (LVN). Two case...

A Randomized Controlled Study of a Fully Liquid DTaP-IPV-HB-PRP-T Hexavalent Vaccine for Primary and Booster Vaccinations of Healthy Infants and Toddlers in Latin America.

Science.gov (United States)

López, Pío; Arguedas Mohs, Adriano; Abdelnour Vásquez, Arturo; Consuelo-Miranda, Maria; Feroldi, Emmanuel; Noriega, Fernando; Jordanov, Emilia; B Chir, Siham; Zambrano, Betzana

2017-11-01

Hexavalent diphtheria-tetanus-acellular pertussis-inactivated poliovirus-hepatitis B-Haemophilus influenzae type b (DTaP-IPV-HB-PRP-T)-containing vaccines are increasingly the standard of care. This study evaluated the primary series (NCT01177722) and booster (NCT01444781) of a fully liquid DTaP-IPV-HB-PRP-T vaccine in Latin America. Infants (N = 1375) received hepatitis B vaccine at birth and were randomized to one of 3 batches of the investigational DTaP-IPV-HB-PRP-T or licensed control vaccine (DTaP-HB-IPV//PRP-T) at 2-4 to 6 months of age, coadministered with 7-valent pneumococcal conjugate vaccine (PCV7) (2-4-6 months) and rotavirus vaccine (2-4 months). A booster of either DTaP-IPV-HB-PRP-T or control was given at 12-24 months, coadministered with PCV7. Immunogenicity was assessed by validated assays and safety from parental reports. Primary series seroprotection and vaccine response rates were equivalent for DTaP-IPV-HB-PRP-T batches. For pooled batches, noninferiority to the control vaccine was demonstrated for each antigen. There were no descriptive differences in antibody persistence or booster response between DTaP-IPV-HB-PRP-T and the control. The booster responses to either vaccine following DTaP-IPV-HB-PRP-T primary series or to DTaP-IPV-HB-PRP-T following a control vaccine primary series were similar. The anti-aP component (filamentous hemagglutinin [FHA] and pertussis toxin [PT]) vaccine response and anti-Haemophilus influenzae type b (PRP) series seroprotection (≥0.15 µg/mL) rates were ≥73.0% after 2 primary series doses. Antipyretics had no effect on the immune response, and an extra (oral) polio vaccination had no effect on the antipolio booster response. Responses to PCV7 and rotavirus vaccine were similar for each coadministration. There were no safety concerns observed with any vaccine. These results confirm the suitability of the fully liquid DTaP-IPV-HB-PRP-T vaccine for primary and booster vaccination of infants.

Whooping cough in school age children presenting with persistent cough in UK primary care after introduction of the preschool pertussis booster vaccination: prospective cohort study.

Science.gov (United States)

Wang, Kay; Fry, Norman K; Campbell, Helen; Amirthalingam, Gayatri; Harrison, Timothy G; Mant, David; Harnden, Anthony

2014-06-24

To estimate the prevalence and clinical severity of whooping cough (pertussis) in school age children presenting with persistent cough in primary care since the introduction and implementation of the preschool pertussis booster vaccination. Prospective cohort study (November 2010 to December 2012). General practices in Thames Valley, UK. 279 children aged 5 to 15 years who presented in primary care with a persistent cough of two to eight weeks' duration. Exclusion criteria were cough likely to be caused by a serious underlying medical condition, known immunodeficiency or immunocompromise, participation in another clinical research study, and preschool pertussis booster vaccination received less than one year previously. Evidence of recent pertussis infection based on an oral fluid anti-pertussis toxin IgG titre of at least 70 arbitrary units. Cough frequency was measured in six children with laboratory confirmed pertussis. 56 (20%, 95% confidence interval 16% to 25%) children had evidence of recent pertussis infection, including 39 (18%, 13% to 24%) of 215 children who had been fully vaccinated. The risk of pertussis was more than three times higher (21/53; 40%, 26% to 54%) in children who had received the preschool pertussis booster vaccination seven years or more previously than in those who had received it less than seven years previously (20/171; 12%, 7% to 17%). The risk of pertussis was similar between children who received five and three component preschool pertussis booster vaccines (risk ratio for five component vaccine 1.14, 0.64 to 2.03). Four of six children in whom cough frequency was measured coughed more than 400 times in 24 hours. Pertussis can still be found in a fifth of school age children who present in primary care with persistent cough and can cause clinically significant cough in fully vaccinated children. These findings will help to inform consideration of the need for an adolescent pertussis booster vaccination in the United Kingdom. UK

A randomised controlled trial and cost-effectiveness evaluation of 'booster' interventions to sustain increases in physical activity in middle-aged adults in deprived urban neighbourhoods.

Science.gov (United States)

Goyder, Elizabeth; Hind, Daniel; Breckon, Jeff; Dimairo, Munyaradzi; Minton, Jonathan; Everson-Hock, Emma; Read, Simon; Copeland, Robert; Crank, Helen; Horspool, Kimberly; Humphreys, Liam; Hutchison, Andrew; Kesterton, Sue; Latimer, Nicolas; Scott, Emma; Swaile, Peter; Walters, Stephen J; Wood, Rebecca; Collins, Karen; Cooper, Cindy

2014-02-01

More evidence is needed on the potential role of 'booster' interventions in the maintenance of increases in physical activity levels after a brief intervention in relatively sedentary populations. To determine whether objectively measured physical activity, 6 months after a brief intervention, is increased in those receiving physical activity 'booster' consultations delivered in a motivational interviewing (MI) style, either face to face or by telephone. Three-arm, parallel-group, pragmatic, superiority randomised controlled trial with nested qualitative research fidelity and geographical information systems and health economic substudies. Treatment allocation was carried out using a web-based simple randomisation procedure with equal allocation probabilities. Principal investigators and study statisticians were blinded to treatment allocation until after the final analysis only. Deprived areas of Sheffield, UK. Previously sedentary people, aged 40-64 years, living in deprived areas of Sheffield, UK, who had increased their physical activity levels after receiving a brief intervention. Participants were randomised to the control group (no further intervention) or to two sessions of MI, either face to face ('full booster') or by telephone ('mini booster'). Sessions were delivered 1 and 2 months post-randomisation. The primary outcome was total energy expenditure (TEE) per day in kcal from 7-day accelerometry, measured using an Actiheart device (CamNtech Ltd, Cambridge, UK). Independent evaluation of practitioner competence was carried out using the Motivational Interviewing Treatment Integrity assessment. An estimate of the per-participant intervention costs, resource use data collected by questionnaire and health-related quality of life data were analysed to produce a range of economic models from a short-term NHS perspective. An additional series of models were developed that used TEE values to estimate the long-term cost-effectiveness. In total, 282 people were

Feasibility study of a pressure-fed engine for a water recoverable space shuttle booster. Volume 1: Executive summary

Science.gov (United States)

1972-01-01

An overview is presented of the results of the analyses conducted in support of the selected engine system for the pressure-fed booster stage. During initial phases of the project, a gimbaled, regeneratively cooled, fixed thrust engine having a coaxial pintle injector was selected as optimum for this configuration.

Adaptive immune responses to booster vaccination against yellow fever virus are much reduced compared to those after primary vaccination

DEFF Research Database (Denmark)

Kongsgaard, Michael; Bassi, Maria Rosaria; Rasmussen, Michael

2017-01-01

Outbreaks of Yellow Fever occur regularly in endemic areas of Africa and South America frequently leading to mass vaccination campaigns straining the availability of the attenuated Yellow Fever vaccine, YF-17D. The WHO has recently decided to discontinue regular booster-vaccinations since a single...... vaccination is deemed to confer life-long immune protection. Here, we have examined humoral (neutralizing antibody) and cellular (CD8 and CD4 T cell) immune responses in primary and booster vaccinees (the latter spanning 8 to 36 years after primary vaccination). After primary vaccination, we observed strong...... cellular immune responses with T cell activation peaking ≈2 weeks and subsiding to background levels ≈ 4 weeks post-vaccination. The number of antigen-specific CD8+ T cells declined over the following years. In >90% of vaccinees, in vitro expandable T cells could still be detected >10 years post-vaccination...

A Project Of The 2.5 Gev Booster-synchrotron In Binp

CERN Document Server

Barbashin, V M; Kremyanskaya, E V; Kvardakov, V A; Levichev, E B; Mishnev, S I; Skrinsky, A N; Smaluk, V V

2004-01-01

A project of the 2.5 GeV booster synchrotron to provide effective injection of electron and positron beams into VEPP-2000 and VEPP-4M storage rings, and for future facilities, is developing in BINP. The beams are injected to synchrotron at 510 MeV energy from a damping ring, which is the part of the new injection facility [1]. Small transverse size of the beam extracted from the damping ring allows us to design the synchrotron with rather small acceptance. Therefore, the aperture can be reduced essentially, which also decreases dimensions of the magnets and their power-consuming. In this report, the synchrotron parameters are presented, the basic systems are briefly described.

Dynamic aperture and performance of the SSC low energy booster lattice

International Nuclear Information System (INIS)

Pilat, F.; Bourianoff, G.; Cole, B.; Talman, R.; York, R.

1991-05-01

A systematic study of lattice designs proposed for the SSC Low Energy Booster has been performed, where the dynamic behavior of high transition gamma lattices is compared with that of a simpler FODO- like machine. After optimization of the transverse tunes, the dynamic aperture is determined by tracking the chromaticity corrected, ''ideal'' lattices, where the only sources on nonlinearity are the chromaticity sextupoles. The robustness of the lattices against misalignment, systematic and random errors is then evaluated and error compensation schemes worked out. The computational speed of the TEAPOT code has been greatly enhanced by porting and running its tracking core on the Intel iPSC/860 parallel computer. 7 refs., 5 figs., 3 tabs

Understanding and improving the high field orbit in the Fermilab Booster

International Nuclear Information System (INIS)

Chao, Y.; Ketcham, L.; Moore, C.D.

1989-03-01

With the implementation of the BPM system in the Fermilab Booster, complete survey data of the main magnets have been employed to determine magnet moving schemes to correct the high field orbit at 8 GeV kinetic energy and to understand the global pattern of the high field orbit in both planes. Considerable success has been achieved in the former task. We also obtained reasonable understanding in the later effort, given the multitude of factors that have to be dealt with. In this paper an account is given of the survey record, the orbit correction exercise, and the effort to reconstruct the high field orbit based on the survey records. 2 refs., 7 figs., 1 tab

Design, fabrication, and calibration of curved integral coils for measuring transfer function, uniformity, and effective length of LBL ALS [Lawrence Berkeley Laboratory Advanced Light Source] Booster Dipole Magnets

International Nuclear Information System (INIS)

Green, M.I.; Nelson, D.; Marks, S.; Gee, B.; Wong, W.; Meneghetti, J.

1989-03-01

A matched pair of curved integral coils has been designed, fabricated and calibrated at Lawrence Berkeley Laboratory for measuring Advanced Light Source (ALS) Booster Dipole Magnets. Distinctive fabrication and calibration techniques are described. The use of multifilar magnet wire in fabrication integral search coils is described. Procedures used and results of AC and DC measurements of transfer function, effective length and uniformity of the prototype booster dipole magnet are presented in companion papers. 8 refs

Improved Longitudinal Blow-up and Shaving in the Booster

CERN Document Server

Hancock, S

2013-01-01

The low-intensity proton beam for p-Pb collisions in the LHC did not come back in the Booster at the beginning of 2013 anything like it had been set up at the end of 2012. In particular there were unexplained intensity fluctuations of ±100%. Although the root cause of the drift in performance was never established, its investigation revealed long-standing issues in the longitudinal plane which, when corrected, allowed single-bunch beams to be delivered with unprecedented reproducibility and control of both intensity and longitudinal emittance. The new approach was adopted for the ion run and subsequently for MDs at higher intensities, where it made possible a robust control of intensity at constant 6D phase space volume. Post-LS1, it may even provide a platform upon which to build a more exotic controlled longitudinal blow-up to generate higher intensity bunches with a flattened line density.

A Randomized Controlled Trial to Evaluate a Potential Hepatitis B Booster Vaccination Strategy Using Combined Hepatitis A and B Vaccine.

Science.gov (United States)

Li, Fangjun; Hu, Yuansheng; Zhou, Youming; Chen, Lixin; Xia, Wei; Song, Yufei; Tan, Zhengliang; Gao, Lidong; Yang, Zhong; Zeng, Gang; Han, Xing; Li, Junhua; Li, Jing

2017-05-01

Booster doses could play a major role in no responders or low responders to primary hepatitis B (HB) vaccine. Planed time point for hepatitis A vaccination in China provides a good opportunity to carry out HB booster dose by using combined hepatitis A and B vaccine. A randomized, double-blinded clinical trial was conducted to compare the immunogenicity and safety of toddlers 18-24 months of age receiving 3 different vaccination regimens: 2 doses of inactivated hepatitis A vaccine (group 1), 1 dose of inactivated hepatitis A vaccine plus 1 dose of combined hepatitis A and B vaccine (group 2) or 2 doses of combined hepatitis A and B vaccine (group 3). All 3 groups showed 100% seroprotection for antihepatitis A virus antibody after vaccination. Seroprotection rate for anti-HB antibody before vaccination ranged from 79.5% to 92.9% in the 3 groups. After second inoculation, anti-HBs seroprotection increased from 92.9% to 100% in group 2 with postvaccination geometric mean concentration (GMC) of 2258.3 mIU/mL and from 79.5% to 98.9% in group 3 with postvaccination GMC of 2055.3 mIU/mL. The adverse events were not statistically different among groups (P = 0.345). Combined hepatitis A and B vaccine could stimulate high level of both antihepatitis A virus and anti-HBs antibodies and not increase adverse events, providing a new choice for HB booster.

Booster Sessions Enhance the Long-Term Effectiveness of Spaced Retrieval in Older Adults with Probable Alzheimer's Disease

Science.gov (United States)

Cherry, Katie E.; Hawley, Karri S.; Jackson, Erin M.; Boudreaux, Emily O.

2009-01-01

Six older adults with probable Alzheimer's disease (AD) were trained to recall a name-face association using the spaced retrieval technique. In this study, we retested these persons in a 6-month follow-up program. For half of the participants, three booster sessions were administered at 6, 12, and 18 weeks after original training to promote…

Three-dimensional model of a liquid-cooled, low energy booster, radio-frequency cavity tuner at the superconducting super collider

International Nuclear Information System (INIS)

Ranganathan, R.; Propp, A.; Campbell, B.; Dao, B.

1994-01-01

A three-dimensional computational heat transfer and fluid flow model was developed to analyze a forced-flow, liquid-cooled, low energy booster (LEB), radio-frequency (RF) cavity, tuner concept. The results for a commercial dielectric heat transfer fluid indicated safe temperatures in the ferrite

Three-dimensional model of a liquid-cooled, low energy booster radio- frequency cavity tuner at the Superconducting Super Collider

Energy Technology Data Exchange (ETDEWEB)

Ranganathan, R.; Propp, A.; Campbell, B.; Dao, B.

1993-04-01

A three-dimensional computational heat transfer and fluid flow model was developed to analyze a forced-flow, liquid-cooled, low energy booster (LEB) radio-frequency (RF) cavity tuner concept. The results for a commercial dielectric heat transfer fluid indicated safe temperatures in the ferrite.

Three-dimensional model of a liquid-cooled, low energy booster radio- frequency cavity tuner at the Superconducting Super Collider

International Nuclear Information System (INIS)

Ranganathan, R.; Propp, A.; Campbell, B.; Dao, B.

1993-04-01

A three-dimensional computational heat transfer and fluid flow model was developed to analyze a forced-flow, liquid-cooled, low energy booster (LEB) radio-frequency (RF) cavity tuner concept. The results for a commercial dielectric heat transfer fluid indicated safe temperatures in the ferrite

Feasibility study of a pressure fed engine for a water recoverable space shuttle booster Volume 2: Technical, phase A effort

Science.gov (United States)

1972-01-01

Design and systems considerations are presented on an engine concept selection for further preliminary design and program evaluation. These data have been prepared from a feasibility study of a pressure-fed engine for the water recoverable space shuttle booster.

Thermodynamic analysis of transcritical CO{sub 2} booster refrigeration systems in supermarket

Energy Technology Data Exchange (ETDEWEB)

Ge, Y.T., E-mail: yunting.ge@brunel.ac.u [Mechanical Engineering, School of Engineering and Design, Brunel University, Uxbridge, Middlesex UB8 3PH (United Kingdom); Tassou, S.A. [Mechanical Engineering, School of Engineering and Design, Brunel University, Uxbridge, Middlesex UB8 3PH (United Kingdom)

2011-04-15

Research highlights: {yields} The CO{sub 2} booster systems are widely applied in supermarket refrigeration. {yields} Control optimisation can improve the performance of the CO{sub 2} refrigeration systems. {yields} The effects of some important parameters on the system performance are examined. {yields} The optimal high-side pressure in the transcritical cycles is established and derived. -- Abstract: Due to less environmental impact, the CO{sub 2} booster refrigeration system has been widely applied in the modern supermarket as a substitute for the conventional R404A multiplex system. However, the performance efficiency of the CO{sub 2} system still requires further improvement in order to save energy; thus, one of the most efficient techniques would be to investigate and employ the optimal controls for refrigerant high side pressures at various operating states. In this paper, the possible parameters affecting system efficiency of the CO{sub 2} system in the transcritical cycle at a higher ambient air temperature are identified through thermodynamic analysis, but cannot be quantified mathematically because of the high non-linearity involved. Instead, sensitive analysis of the system by means of the thermodynamic model is used to examine the effects of parameters including high side refrigerant pressure, ambient air temperature, refrigerant intermediate pressure, and medium and low evaporating temperatures, superheating, effectiveness of suction line heat exchanger, and compressor efficiency on system performance. Consequently, the optimal high side pressure in the transcritical cycle is established and derived as a function of three important parameters consisting of ambient air temperature, the effectiveness of suction line heat exchanger and compressor efficiency. In addition, optimal operating parameters such as the intermediate pressure are also proposed to improve the system performance.

An overview of Booster and AGS Polarized Proton Operations during Run 17

Energy Technology Data Exchange (ETDEWEB)

Zeno, K. [Brookhaven National Lab. (BNL), Upton, NY (United States)

2017-10-11

There were only a few differences in the setup between this year’s Polarized Proton run and the previous one (Run 15). Consequently, this note will focus on these differences as well as a few more notable studies done during the course of the run. This year, the Booster input intensity was kept around 7e11 for the majority of the run whereas in Run 15 it was kept around 9e11. It was lowered because there was some indication that the source polarization was higher with this lower input. Some of the polarization measurements that motivated this change will be discussed. Both the emittance and polarization on the AGS flattop show intensity dependence, thought to be related to the peak current, especially early in the AGS acceleration ramp. In Run 15, the AGS Rf was configured for h=8, but in this run h=6 was used to reduce the peak current and also to allow for the possibility of using a dual harmonic to reduce it further. Eventually, a dual harmonic configuration was used for the first 100 ms or so of the AGS acceleration cycle. Two cavities were set to h=12 and phased differently than the other 8 to accomplish this. Quad pumping was also used at Booster extraction to make the bunch injected into the AGS wider in order to match the dual harmonic bucket right at injection. This configuration, which was used for the majority of the run, will be described. Measurements of the intensity dependence of the transverse emittance and polarization with and without it will be compared.

Measurement of transverse emittance in the Fermilab booster

Energy Technology Data Exchange (ETDEWEB)

Graves, William Sproull [Wisconsin U., Madison

1994-01-01

A new beam profile monitor has been built and installed in the Fermilab Booster synchrotron. It nondestructively measures the beam's vertical density distribution on a fast turn-by-turn basis. This enables one to measure the beam's transverse emittance and to observe emittance growth as it occurs. For high intensities (>2 times 10^{12 } protons), the normalized 95% emittance was observed to grow from 6pi mm-mrad at injection to 16pi mm-mrad at extraction. The initial (<5 msec) emittance growth and beam losses are shown to be caused by the space charge tune shift onto integer and 1/2 integer resonance lines. The growth near injection accounts for approximately 40% of the observed emittance increase throughout the acceleration cycle. The remaining 60% is due to two factors: slow linear growth due to betatron-motion driven by noise in the rf system; and faster growth after the transition energy that is caused by coupling of the longitudinal beam motion into the transverse planes.

A Global Network Alignment Method Using Discrete Particle Swarm Optimization.

Science.gov (United States)

Huang, Jiaxiang; Gong, Maoguo; Ma, Lijia

2016-10-19

Molecular interactions data increase exponentially with the advance of biotechnology. This makes it possible and necessary to comparatively analyse the different data at a network level. Global network alignment is an important network comparison approach to identify conserved subnetworks and get insight into evolutionary relationship across species. Network alignment which is analogous to subgraph isomorphism is known to be an NP-hard problem. In this paper, we introduce a novel heuristic Particle-Swarm-Optimization based Network Aligner (PSONA), which optimizes a weighted global alignment model considering both protein sequence similarity and interaction conservations. The particle statuses and status updating rules are redefined in a discrete form by using permutation. A seed-and-extend strategy is employed to guide the searching for the superior alignment. The proposed initialization method "seeds" matches with high sequence similarity into the alignment, which guarantees the functional coherence of the mapping nodes. A greedy local search method is designed as the "extension" procedure to iteratively optimize the edge conservations. PSONA is compared with several state-of-art methods on ten network pairs combined by five species. The experimental results demonstrate that the proposed aligner can map the proteins with high functional coherence and can be used as a booster to effectively refine the well-studied aligners.

Primary and booster vaccination in Latin American children with a DTPw-HBV/Hib combination: a randomized controlled trial.

Science.gov (United States)

Espinoza, Felix; Tregnaghi, Miguel; Gentile, Angela; Abarca, Katia; Casellas, Javier; Collard, Alix; Lefevre, Inge; Jacquet, Jeanne-Marie

2010-10-15

Diphtheria-tetanus-whole-cell pertussis (DTPw)-based combination vaccines are an attractive option to rapidly achieve high coverage and protection against other important pathogens, such as hepatitis B virus (HBV) and Haemophilus influenzae type B (Hib). To ensure adequate antigen supply, GlaxoSmithKline Biologicals has introduced a new DTPw antigen source and developed a new DTPw-HBV/Hib combination vaccine containing a reduced amount of Hib polyribosylribitol phosphate (PRP). This study was undertaken to compare the immunogenicity and reactogenicity of this new DTPw-HBV/Hib vaccine with a licensed DTPw-HBV/Hib vaccine (Tritanrix™-HBV/Hib). This was a randomized, partially-blind, multicenter study in three countries in Latin America (Argentina, Chile and Nicaragua). Healthy children received either the new DTPw-HBV/Hib vaccine (1 of 3 lots; n = 439; double-blind) or Tritanrix™-HBV/Hib (n = 146; single-blind) co-administered with oral poliovirus vaccine (OPV) at 2, 4 and 6 months, with a booster dose at 18-24 months. One month after the end of the 3-dose primary vaccination course, the new DTPw-HBV/Hib vaccine was non-inferior to Tritanrix™-HBV/Hib in terms of seroprotection/vaccine response rates for all component antigens; ≥97.3% and ≥93.9% of subjects in the two groups, respectively, had seroprotective levels of antibodies against diphtheria, tetanus, hepatitis B and Hib and a vaccine response to the pertussis component. Persistence of antibodies against all vaccine antigens was comparable between groups, with marked increases in all antibody concentrations after booster administration in both groups. Both vaccines were generally well-tolerated as primary and booster doses. Results confirm the suitability of this new DTPw-HBV/Hib vaccine comprising antigens from a new source and a reduced PRP content for inclusion into routine childhood vaccination programs. http://www.clinicaltrials.gov NCT00332566.

Design criteria and candidate electrical power systems for a reusable Space Shuttle booster.

Science.gov (United States)

Merrifield, D. V.

1972-01-01

This paper presents the results of a preliminary study to establish electrical power requirements, investigate candidate power sources, and select a representative power generation concept for the NASA Space Shuttle booster stage. Design guidelines and system performance requirements are established. Candidate power sources and combinations thereof are defined and weight estimates made. The selected power source concept utilizes secondary silver-zinc batteries, engine-driven alternators with constant speed drive, and an airbreathing gas turbine. The need for cost optimization, within safety, reliability, and performance constraints, is emphasized as being the most important criteria in design of the final system.

Space shuttle solid rocket booster water entry cavity collapse loads

Science.gov (United States)

Keefe, R. T.; Rawls, E. A.; Kross, D. A.

1982-01-01

Solid rocket booster cavity collapse flight measurements included external pressures on the motor case and aft skirt, internal motor case pressures, accelerometers located in the forward skirt, mid-body area, and aft skirt, as well as strain gages located on the skin of the motor case. This flight data yielded applied pressure longitudinal and circumferential distributions which compare well with model test predictions. The internal motor case ullage pressure, which is below atmospheric due to the rapid cooling of the hot internal gas, was more severe (lower) than anticipated due to the ullage gas being hotter than predicted. The structural dynamic response characteristics were as expected. Structural ring and wall damage are detailed and are considered to be attributable to the direct application of cavity collapse pressure combined with the structurally destabilizing, low internal motor case pressure.

Meningococcal serogroup C immunogenicity, antibody persistence and memory B-cells induced by the monovalent meningococcal serogroup C versus quadrivalent meningococcal serogroup ACWY conjugate booster vaccine: A randomized controlled trial.

Science.gov (United States)

van Ravenhorst, Mariëtte B; van der Klis, Fiona R M; van Rooijen, Debbie M; Knol, Mirjam J; Stoof, Susanne P; Sanders, Elisabeth A M; Berbers, Guy A M

2017-08-24

Adolescents are considered the key transmitters of meningococci in the population. Meningococcal serogroup C (MenC) antibody levels wane rapidly after MenC conjugate vaccination in young children, leaving adolescents with low antibody levels. In this study, we compared MenC immune responses after booster vaccination in adolescence with either tetanus toxoid conjugated MenC (MenC-TT) or MenACWY (MenACWY-TT) vaccine, and aimed to establish an optimal age for this booster. Healthy 10-, 12-, and 15-year-olds, who received a single dose of MenC-TT vaccine in early childhood, were randomized to receive MenC-TT or MenACWY-TT vaccine. MenC serum bactericidal antibody (rSBA) titers, MenC polysaccharide (PS) specific IgG, IgG1 and IgG2 and MenC-specific IgG and IgA memory B-cells were determined before, one month and one year after the booster. Non-inferiority was tested by comparing geometric mean titers (GMTs) between vaccinees at one year. Of 501 participants, 464 (92.6%) were included in the 'according to protocol' cohort analysis. At one month, all participants developed high MenC rSBA titers (>24,000 in all groups) and MenC-PS-specific IgG levels. Non-inferiority was not demonstrated one year after the booster with higher MenC GMTs after the monovalent vaccine, but 462/464 (99.6%) participants maintained protective MenC rSBA titers. IgG levels mainly consisted of IgG1, but similar levels of increase were observed for IgG1 and IgG2. Both vaccines induced a clear increase in the number of circulating MenC-PS specific IgG and IgA memory B-cells. Between one month and one year, the highest antibody decay rate was observed in the 10-year-olds. Both MenC-TT and MenACWY-TT vaccines induced robust protective MenC immune responses after the booster vaccination, although non-inferiority could not be demonstrated for the MenACWY-TT vaccine after one year. Our results underline the importance of optimal timing of a meningococcal booster vaccination to protect against MenC disease

Glide back booster wind tunnel model testing

Science.gov (United States)

Pricop, M. V.; Cojocaru, M. G.; Stoica, C. I.; Niculescu, M. L.; Neculaescu, A. M.; Persinaru, A. G.; Boscoianu, M.

2017-07-01

Affordable space access requires partial or ideally full launch vehicle reuse, which is in line with clean environment requirement. Although the idea is old, the practical use is difficult, requiring very large technology investment for qualification. Rocket gliders like Space Shuttle have been successfullyoperated but the price and correspondingly the energy footprint were found not sustainable. For medium launchers, finally there is a very promising platform as Falcon 9. For very small launchers the situation is more complex, because the performance index (payload to start mass) is already small, versus medium and heavy launchers. For partial reusable micro launchers this index is even smaller. However the challenge has to be taken because it is likely that in a multiyear effort, technology is going to enable the performance recovery to make such a system economically and environmentally feasible. The current paper is devoted to a small unitary glide back booster which is foreseen to be assembled in a number of possible configurations. Although the level of analysis is not deep, the solution is analyzed from the aerodynamic point of view. A wind tunnel model is designed, with an active canard, to enablea more efficient wind tunnel campaign, as a national level premiere.

NSRL Extraction Bump Control in the Booster

International Nuclear Information System (INIS)

Brennan, L.

2008-01-01

Due to inadequacies in the user interface of the booster orbit control system, a number of new tools were developed. The first priority was an accurate calculation of the winding currents given specific displacements at each extraction septa. Next, the physical limits of the power supplies (±600 amps) needed to be taken into account. In light of this limit, a system is developed that indicates to the user what the allowed values of one bump parameter are once the other two have been specified. Finally, techniques are developed to account for the orbit behavior once power supplies are requested to exceed their ±600 amp limit. This includes a recalculation of bump parameters and a calculation of the amplitude of the residuals. Following this, possible areas for further development are outlined. These techniques were computationally developed in Mathematica and tested in the Methodical Accelerator Design (MAD) program before they were implemented into the control system. At the end, a description of the implementation of these techniques in a new interface is described. This includes a depiction of the appearance and functionality of the graphical user interface, a description of the input and output flow, and an outline of how each important calculation is performed

Spatial correction factors for YALINA Booster facility loaded with medium and low enriched fuels

International Nuclear Information System (INIS)

Talamo, A.; Gohar, Y.; Bournos, V.; Fokov, Y.; Kiyavitskaya, H.; Routkovskaya, C.

2012-01-01

The Bell and Glasstone spatial correction factor is used in analyses of subcritical assemblies to correct the experimental reactivity as function of the detector position. Besides the detector position, several other parameters affect the correction factor: the energy weighting function of the detector, the detector size, the energy-angle distribution of source neutrons, and the reactivity of the subcritical assembly. This work focuses on the dependency of the correction factor on the detector material and it investigates the YALINA Booster subcritical assembly loaded with medium (36%) and low (10%) enriched fuels. (authors)

Spatial correction factors for YALINA Booster facility loaded with medium and low enriched fuels

Energy Technology Data Exchange (ETDEWEB)

Talamo, A.; Gohar, Y. [Argonne National Laboratory, 9700 S. Cass Ave, Argonne, IL 60439 (United States); Bournos, V.; Fokov, Y.; Kiyavitskaya, H.; Routkovskaya, C. [Joint Inst. for Power and Nuclear Research-Sosny, 99 Academician A.K.Krasin Str, Minsk 220109 (Belarus)

2012-07-01

The Bell and Glasstone spatial correction factor is used in analyses of subcritical assemblies to correct the experimental reactivity as function of the detector position. Besides the detector position, several other parameters affect the correction factor: the energy weighting function of the detector, the detector size, the energy-angle distribution of source neutrons, and the reactivity of the subcritical assembly. This work focuses on the dependency of the correction factor on the detector material and it investigates the YALINA Booster subcritical assembly loaded with medium (36%) and low (10%) enriched fuels. (authors)

USBI Booster Production Company's Hazardous Waste Management Program at the Kennedy Space Center, FL

Science.gov (United States)

Venuto, Charles

1987-01-01

In response to the hazardous-waste generating processes associated with the launch of the Space Shuttle, a hazardous waste management plan has been developed. It includes waste recycling, product substitution, waste treatment, and waste minimization at the source. Waste material resulting from the preparation of the nonmotor segments of the solid rocket boosters include waste paints (primer, topcoats), waste solvents (methylene chloride, freon, acetone, toluene), waste inorganic compounds (aluminum anodizing compound, fixer), and others. Ways in which these materials are contended with at the Kennedy Space Center are discussed.

Beam transfer between the coupled cavity linac and the low energy booster synchrotron for the SSC [Superconducting Super Collider

International Nuclear Information System (INIS)

Bhandari, R.K.; Penner, S.

1990-09-01

Ion optical design of the transfer line, which will be used to inject H - beam at 600 MeV from the Coupled Cavity Linac (CCL) into the Low Energy Booster (LEB) synchrotron, is described. Space charge effects of up to 50 mA average beam current have been taken into account

Development of small solid rocket boosters for the ILR-33 sounding rocket

Science.gov (United States)

Nowakowski, Pawel; Okninski, Adam; Pakosz, Michal; Cieslinski, Dawid; Bartkowiak, Bartosz; Wolanski, Piotr

2017-09-01

This paper gives an overview of the development of a 6000 Newton-class solid rocket motor for suborbital applications. The design configuration and results of interior ballistics calculations are given. The initial use of the motor as the main propulsion system of the H1 experimental in-flight test platform, within the Polish Small Sounding Rocket Program, is presented. Comparisons of theoretical and experimental performance are shown. Both on-ground and in-flight tests are discussed. A novel composite-case manufacturing technology, which enabled to reach high propellant mass fractions, was validated and significant cost-reductions were achieved. This paper focuses on the process of adapting the design for use as the booster stage of the ILR-33 sounding rocket, under development at the Institute of Aviation in Warsaw, Poland. Parallel use of two of the flight-proven rocket motors along with the main stage is planned. The process of adapting the rocket motor for booster application consists of stage integration, aerothermodynamics and reliability analyses. The separation mechanism and environmental impact are also discussed within this paper. Detailed performance analysis with focus on propellant grain geometry is provided. The evolution of the design since the first flights of the H1 rocket is covered and modifications of the manufacturing process are described. Issues of simultaneous ignition of two motors and their non-identical performance are discussed. Further applications and potential for future development are outlined. The presented results are based on the initial work done by the Rocketry Group of the Warsaw University of Technology Students' Space Association. The continuation of the Polish Small Sounding Rocket Program on a larger scale at the Institute of Aviation proves the value of the outcomes of the initial educational project.

Chinese modify CZ-2/3 rocket boosters, focus on commercial launch market

Science.gov (United States)

Covault, C.

1985-07-01

A program underway in the People's Republic of China to modify the Titan-class CZ-2/3 satellite-launch and ICBM boosters is described on the basis of a recent visit to the manufacturing plant in Shanghai. The present two-stage CZ-2 and three-stage CZ-3 can place 5000 lbs in LEO or 3080 lbs in GEO, respectively, and are produced on a custom basis with a delivery time of about 2 yrs. Modifications introduced include 4 x 6-ft fins and a pogo-suppression system for the four-engine first stage and a steel support band for the combustion chamber of the 80-ton-thrust second-stage main engine.

Emittance Measurements For Future LHC Beams Using The PS Booster Measurement Line

CERN Document Server

Abelleira, Jose; Mikulec, Bettina; Di Giovanni, Gian Piero; CERN. Geneva. ATS Department

2017-01-01

The CERN PS Booster measurement line contains three pairs of SEM grids separated by drift space that measures the beam size in both planes. The combined analysis of these grids allows calculating a value for the transverse beam emittances. The precision of such a measurement depends on the ratio of RMS beam size and wire spacing. Within the LIU-PSB upgrade the extraction kinetic energy of the PSB will be increased from the current 1.4 GeV to 2.0 GeV. This will result in smaller transverse beam sizes for some of the future beams. The present layout of the transverse emittance measurement line is reviewed to verify if it will satisfy future requirements.

Magnetic field measurements on the perpendicular biased RF booster cavity for the proposed TRIUMF KAON Factory

International Nuclear Information System (INIS)

Enchevich, I.B.; Poirier, R.L.

1992-08-01

The successful operation of the full scale KAON Factory Ferrite tuned Booster Accelerating Cavity Prototype allowed us to do ac magnetic field measurements in the tuner. The field measured is close to that calculated. The measured data are discussed. They may be used for reliable computation of the perturbation of the beam dynamics due to the ferrite biasing magnetic field. Methods to compensate the disturbing magnetic fields are discussed. 7 refs., 7 figs

Design of LINAC4, A New Injector for the CERN Booster

CERN Document Server

Garoby, R; Lombardi, A M; Rossi, C; Vretenar, M; Gerigk, F

2004-01-01

A new H- linac (Linac4) is presently under study at CERN. This accelerator, based on normal conducting structures at 352 and 704 MHz, will provide a 30 mA 160 MeV H- beam to the CERN PS Booster (PSB), thus overcoming the present space-charge bottleneck at injection with a 50 MeV proton beam. Linac4 is conceived as the first stage of a future 2.2 GeV superconducting linac (SPL) and it is therefore designed for a higher duty cycle than necessary for the PSB. This paper discusses the design choices, presents the layout of the facility and illustrates the advantages for the LHC and other CERN users. The R&D and construction strategy, which mainly relies upon international collaborations, is also presented.

Effects of parent and child characteristics on participation and outcome of an individualized booster parent intervention for children with externalizing behaviour

NARCIS (Netherlands)

Stoltz, Sabine; Van Londen, Monique; Dekovic, Maja

2015-01-01

In this study, we examined whether a booster parent training, offered after a cognitive behavioural child intervention, is effective in reduction of aggressive behaviour and changes in parenting. A second aim was to identify parent and child characteristics that influence parental participation.

CERN's PS Booster LLRF renovation : plans and initial beam tests

CERN Document Server

Angoletta, ME; Butterworth, A; Findlay, A; Leinonen, PM; Molendijk, JC; Pedersen, F; Sanchez-Quesada, J; Schokker, M

2010-01-01

In 2008 a project was started to renovate the CERN's PS Booster (PSB) low-level RF (LLRF). Required LLRF capabilities include frequency program, beam phase, radial and synchronization loops. The new LLRF will control the signals feeding the three RF cavities present in each ring; it will also shape the beam in a dual harmonic mode, operate a bunch splitting and create a longitudinal blow-up. The main benefits of this new LLRF are its full remote and cycle-to-cycle controllability, built-in observation capability and flexibility. The overall aim is to improve the robustness, maintainability and reliability of the PSB operation and to make it compatible with the injection from the future Linac4. This paper outlines the main characteristics of the software and hardware building blocks. Initial beam test results and hints on the main milestones and future work are also given.

47 CFR 73.3572 - Processing of TV broadcast, Class A TV broadcast, low power TV, TV translators, and TV booster...

Science.gov (United States)

2010-10-01

... 47 Telecommunication 4 2010-10-01 2010-10-01 false Processing of TV broadcast, Class A TV broadcast, low power TV, TV translators, and TV booster applications. 73.3572 Section 73.3572... Rules Applicable to All Broadcast Stations § 73.3572 Processing of TV broadcast, Class A TV broadcast...

Antibody persistence 5 years after vaccination at 2 to 10 years of age with Quadrivalent MenACWY-CRM conjugate vaccine, and responses to a booster vaccination.

Science.gov (United States)

Block, Stan L; Christensen, Shane; Verma, Bikash; Xie, Fang; Keshavan, Pavitra; Dull, Peter M; Smolenov, Igor

2015-04-27

In a multi-center extension study, children 2-10 years of age, initially vaccinated with one or two doses (2-5 year-olds) or one dose (6-10 year-olds) of quadrivalent meningococcal CRM197-conjugate vaccine (MenACWY-CRM), were assessed five years later for antibody persistence and booster response using serum bactericidal assay with human complement (hSBA). Children 7-10 and 11-15 years of age, who received MenACWY-CRM in the original study, and age-matched vaccine-naïve children, were enrolled in this extension study. After an initial blood draw, children received one dose of MenACWY-CRM as booster or primary dose, with a second blood draw 28 days later. hSBA titers decreased five years after primary vaccination, but were higher than in non-vaccinated controls against serogroups C, W and Y, with substantial proportions having titers ≥8: 7-22% for A, 32-57% for C, 74-83% for W, and 48-54% for Y. Previously-vaccinated children demonstrated booster responses to revaccination against all four serogroups. Responses to primary vaccination in vaccine-naïve controls were lower and similar to primary responses observed in the original study. All vaccinations were generally well tolerated, with no safety concern raised. Approximately half the children vaccinated as 2-10 year-olds maintained protective antibodies against serogroups C, W and Y five years later, but fewer did against serogroup A. Declining titers five years after vaccination and robust booster responses suggest that five years may be an appropriate interval to revaccinate children, subject to epidemiology and delivery considerations. Copyright © 2015 Elsevier Ltd. All rights reserved.

Ketoconazole is inferior to ritonavir as an alternative booster for saquinavir in a once daily regimen in Thai HIV-1 infected patients

NARCIS (Netherlands)

Autar, Reshma Saskia; Wit, Ferdinand W. N. M.; Sankote, Jongkol; Sutthichom, Duanghathai; Kimenai, Elly; Hassink, Elly; Hill, Andrew; Cooper, David A.; Phanuphak, Praphan; Lange, Joep M. A.; Burger, David M.; Ruxrungtham, Kiat

2007-01-01

OBJECTIVE: To improve the pharmacokinetics of protease inhibitors, boosting with low-dose ritonavir is performed. However, toxicity, storage conditions and high costs of antiretroviral treatment may necessitate interruption of ritonavir. Ketoconazole was investigated as a potential booster of

Ketoconazole is inferior to ritonavir as an alternative booster for saquinavir in a once daily regimen in Thai HIV-1 infected patients.

NARCIS (Netherlands)

Autar, R.S.; Wit, F.W.; Sankote, J.; Sutthichom, D.; Kimenai, E.; Hassink, E.A.M.; Hill, A.; Cooper, D.A.; Phanuphak, P.; Lange, J.M.A.; Burger, D.M.; Ruxrungtham, K.

2007-01-01

OBJECTIVE: To improve the pharmacokinetics of protease inhibitors, boosting with low-dose ritonavir is performed. However, toxicity, storage conditions and high costs of antiretroviral treatment may necessitate interruption of ritonavir. Ketoconazole was investigated as a potential booster of

Primary and booster vaccination with DTPw-HB/Hib pentavalent vaccine in Costa Rican children who had received a birth dose of hepatitis B vaccine

Directory of Open Access Journals (Sweden)

Idis Faingezicht

2002-10-01

Full Text Available Objective. The DTPw-HB/Hib pentavalent combination vaccine has been developed following recommendations of the World Health Organization for the introduction of hepatitis B (HB and Haemophilus influenzae type b (Hib vaccines into routine childhood vaccination programs. The objectives of this study were to: 1 analyze the immunogenicity and the reactogenicity of the DTPw-HB/Hib pentavalent combination vaccine in comparison to separate injections of DTPw-HB and Hib vaccines as primary vaccination in a group of children who had received a dose of HB vaccine at birth and 2 in the second year of life to assess the antibody persistence as well as the response to a DTPw-HB/Hib or DTPw/Hib booster. Methods. In the first part of the study (primary-vaccination stage, conducted in 1998-1999, we analyzed the immunogenicity and reactogenicity of the DTPw-HB/Hib combination vaccine in comparison to separate injections of DTPw-HB and Hib vaccines as primary vaccination at 2, 4, and 6 months of age in 207 Costa Rican children who had received a dose of HB vaccine at birth. Later, in the booster-vaccination stage of the study, in 1999-2000, in a subset of the children (69 toddlers, now 15-18 months old, antibody persistence was measured, and response to a DTPw-HB/Hib or DTPw/Hib booster was also assessed. Results. In both primary-vaccination groups, at least 97.5% of the infants reached protective levels of antibodies (seropositivity against the antigens employed in the vaccines. The DTPw-HB/Hib pentavalent combination vaccine did not result in more local reactions than did the DTPw-HB vaccine alone, and, in terms of general reactions, there was no clinically significant difference between the combination or separate injections, and with the pentavalent vaccine having the benefit of needing one less injection. Nine months after the third dose of the primary-vaccination course, antibody persistence was similar in both groups, with over 93% of children still having

Oak Ridge isochronous cyclotron as an energy booster for a 25 MV tandem

International Nuclear Information System (INIS)

Lord, R.S.; Hudson, E.D.; McNeilly, G.S.

1975-01-01

The maximum heavy-ion energy available at Oak Ridge will be substantially increased by using ORIC as an energy booster for the 25 MV ''folded'' tandem now being acquired. Beams of ions with mass up to A = 160, with energy sufficient to overcome the Coulomb barrier on lead, will be produced. The beams will enter the cyclotron through the dee stem and will be directed by a magnet through the fringe and main fields to a stripping foil which lies on the appropriate orbit for acceleration. General orbit and beam transport codes were used to aid in the design of the injection system. (U.S.)

HPLC Characterization of Phenol-Formaldehyde Resole Resin Used in Fabrication of Shuttle Booster Nozzles

Science.gov (United States)

Young, Philip R.

1999-01-01

A reverse phase High Performance Liquid Chromatographic method was developed to rapidly fingerprint a phenol-formaldehyde resole resin similar to Durite(R) SC-1008. This resin is used in the fabrication of carbon-carbon composite materials from which Space Shuttle Solid Rocket Booster nozzles are manufactured. A knowledge of resin chemistry is essential to successful composite processing and performance. The results indicate that a high quality separation of over 35 peaks in 25 minutes were obtained using a 15 cm Phenomenex LUNA C8 bonded reverse phase column, a three-way water-acetonitrile-methanol nonlinear gradient, and LTV detection at 280 nm.

From TBT to booster biocides: Levels and impacts of antifouling along coastal areas of Panama.

Science.gov (United States)

Batista-Andrade, Jahir Antonio; Caldas, Sergiane Souza; Batista, Rodrigo Moço; Castro, Italo Braga; Fillmann, Gilberto; Primel, Ednei Gilberto

2018-03-01

Antifouling biocides in surface sediments and gastropod tissues were assessed for the first time along coastal areas of Panama under the influence of maritime activities, including one of the world's busiest shipping zones: the Panama Canal. Imposex incidence was also evaluated in five muricid species distributed along six coastal areas of Panama. This TBT-related biological alteration was detected in three species, including the first report in Purpura panama. Levels of organotins (TBT, DBT, and MBT) in gastropod tissues and surficial sediments ranged from TBT inputs were observed in areas considered as moderate to highly contaminated mainly by inputs from fishing and leisure boats. Regarding booster biocides, TCMTB and dichlofluanid were not detected in any sample, while irgarol 1051, diuron and DCOIT levels ranged from TBT (149 ng Sn g -1 ) and irgarol 1051 (2.8 ng g -1 ), as well as relevant level of DCOIT (5.7 ng g -1 ), were detected in a marina used by recreational boats. Additionally, relatively high diuron values (14.1 ng g -1 ) were also detected in the Panama Canal associate to a commercial port. DCOIT concentrations were associated with the presence of antifouling paint particles in sediments obtained nearby shipyard or boat maintenance sites. The highest levels of TBT, irgarol 1051, and diuron exceeded international sediment quality guidelines indicating that toxic effects could be expected in coastal areas of Panama. Thus, the simultaneous impacts produced by new and old generations of antifouling paints highlight a serious environmental issue in Panamanian coastal areas. Copyright © 2017 Elsevier Ltd. All rights reserved.

Persistence of the immune response after MenACWY-CRM vaccination and response to a booster dose, in adolescents, children and infants.

Science.gov (United States)

Baxter, Roger; Keshavan, Pavitra; Welsch, Jo Anne; Han, Linda; Smolenov, Igor

2016-05-03

Persistence of bactericidal antibodies following vaccination is extremely important for protection against invasive meningococcal disease, given the epidemiology and rapid progression of meningococcal infection. We present an analysis of antibody persistence and booster response to MenACWY-CRM, in adolescents, children and infants, from 7 clinical studies. Immunogenicity was assessed using the serum bactericidal assay with both human and rabbit complement. Post-vaccination hSBA titers were high, with an age- and serogroup-specific decline in titers up to 1 y and stable levels up to 5 y The waning of hSBA titers over time was more pronounced among infants and toddlers and the greatest for serogroup A. However, rSBA titers against serogroup A were consistently higher and showed little decline over time, suggesting that protection against this serogroup may be sustained. A single booster dose of MenACWY-CRM administered at 3 to 5 y induced a robust immune response in all age groups.

Test results of the AGS Booster low frequency RF system

International Nuclear Information System (INIS)

Sanders, R.T.; Cameron, P.; Damm, R.; Dunbar, A.; Goldman, M.; Kasha, D.; McNerney, A.; Meth, M.; Ratti, A.; Spitz, R.

1993-01-01

The Band II RF system was originally built to support the Booster operations during the acceleration of heavy ions. Designed to sweep from 0.6 to 2.5 MHz, it was build and successfully tested over a much broader range reaching 4 MHz. Voltages up to more than 20 kV were reached over the design frequency range. The system consists of two stations, each of which is made of one single gap cavity directly driven by a grounded cathode push pull power amplifier. The low Q high permeability ferrites needed in the coaxial cavity in order to reach the lower end of the band make tuning extremely easy. Both systems were thoroughly tested both at single frequencies and on a sweep and are now installed in the ring, ready for operations. Static measurements showed no high-loss effects. The Band 11 system has been fully described in a previous paper; presented here are the results of the ''bench'' tests that lead to important performance improvements

Primary and booster vaccination in Latin American children with a DTPw-HBV/Hib combination: a randomized controlled trial

Directory of Open Access Journals (Sweden)

Collard Alix

2010-10-01

Full Text Available Abstract Background Diphtheria-tetanus-whole-cell pertussis (DTPw-based combination vaccines are an attractive option to rapidly achieve high coverage and protection against other important pathogens, such as hepatitis B virus (HBV and Haemophilus influenzae type B (Hib. To ensure adequate antigen supply, GlaxoSmithKline Biologicals has introduced a new DTPw antigen source and developed a new DTPw-HBV/Hib combination vaccine containing a reduced amount of Hib polyribosylribitol phosphate (PRP. This study was undertaken to compare the immunogenicity and reactogenicity of this new DTPw-HBV/Hib vaccine with a licensed DTPw-HBV/Hib vaccine (Tritanrix™-HBV/Hib. Methods This was a randomized, partially-blind, multicenter study in three countries in Latin America (Argentina, Chile and Nicaragua. Healthy children received either the new DTPw-HBV/Hib vaccine (1 of 3 lots; n = 439; double-blind or Tritanrix™-HBV/Hib (n = 146; single-blind co-administered with oral poliovirus vaccine (OPV at 2, 4 and 6 months, with a booster dose at 18-24 months. Results One month after the end of the 3-dose primary vaccination course, the new DTPw-HBV/Hib vaccine was non-inferior to Tritanrix™-HBV/Hib in terms of seroprotection/vaccine response rates for all component antigens; ≥97.3% and ≥93.9% of subjects in the two groups, respectively, had seroprotective levels of antibodies against diphtheria, tetanus, hepatitis B and Hib and a vaccine response to the pertussis component. Persistence of antibodies against all vaccine antigens was comparable between groups, with marked increases in all antibody concentrations after booster administration in both groups. Both vaccines were generally well-tolerated as primary and booster doses. Conclusions Results confirm the suitability of this new DTPw-HBV/Hib vaccine comprising antigens from a new source and a reduced PRP content for inclusion into routine childhood vaccination programs. Trial registration http

Development of synchronized control method for shaking table with booster device. Verification of the capabilities based on both real facility and numerical simulator

International Nuclear Information System (INIS)

Kajii, Shin-ichirou; Yasuda, Chiaki; Yamashita, Toshio; Abe, Hiroshi; Kanki, Hiroshi

2004-01-01

In the seismic design of nuclear power plant, it is recently considered to use probability method in a addition to certainty method. The former method is called Seismic Probability Safety Assessment (Seismic PSA). In case of seismic PSA for some components of a nuclear power plant using a shaking table, it is necessary for some limited conditions with high level of accelerations such as actual conditions. However, it might be difficult to achieve the test conditions that a current shaking table based on hydraulic power system is intended for the test facility. Therefore, we have been planning out a test method in which both a current and another shaking table called a booster device are applied. This paper describes the verification test of a synchronized control between a current shaking table and a booster device. (author)

An ep collider with Ecm = 1 TeV in a VLHC booster tunnel

International Nuclear Information System (INIS)

Barber, D. P.; Chojnacki, E.; Derrick, M.; Friedsam, H.; Gorski, A.; Hanuska, S.; Jagger, J.; Krakauer, D.; Norem, J.; Rotela, E.; Sen, T.; Sharma, S.; Teng, L.; Thompson, K.

1999-01-01

The low field option for the VLHC includes a 3 TeV proton booster with a circumference of 34 km. The authors are studying the option of an electron ring to fit in this tunnel which can produce ep collisions with a luminosity of 1 fb -1 /yr with a center of mass energy of 1 TeV. The machine would utilize superconducting rf and small low field magnets for the approximately 80 GeV electron beam. They describe the vacuum chamber/magnet system, rf power supply requirements, vacuum chamber cooling, interaction regions and installation of the facility in the tunnel, as well as provide preliminary estimates of beam stability and lifetimes

Commercial herbal medicines used as African traditional medicines: Ngoma Herbal Tonic Immune Booster interferes with a rapid urine drug screening test.

Science.gov (United States)

Mothibe, M E; Osuch, E; Kahler-Venter, C P

2017-08-25

The prevalent use of African traditional medicine by the general public has been reported. With commercialisation and marketing, some of the herbal medicines (HMs) used are readily available over the counter, most of them promoted as immune boosters. These commercial HMs have not been taken through clinical trials and other tests that would validate their composition and safety, and other properties such as their effect on laboratory diagnostic tests. To investigate the cross-reactivity of selected HMs with commonly tested drugs of abuse (DoA) using a qualitative rapid urinalysis assay. The six HMs selected were bought from local pharmacies. A rapid urinalysis screening test was performed with the Instant View Multi-Drug of Abuse Test kit from Labstix Diagnostics. Drug-free urine (DFU) was pooled from samples donated by healthy volunteers. Urine samples that had tested positive for DoA were obtained from a pharmacology laboratory. Aliquots of the urine samples were spiked with the HMs in neat and diluted form, and tested at various time intervals. The results for the DFU samples spiked with the HMs remained negative. There were no significant changes in pH or specific gravity of the samples. The results of samples that had tested positive for tetrahydrocannabinol (THC) were not altered by five of the HMs when spiked at 40% v/v. The HM Ngoma Herbal Tonic Immune Booster caused false-negative results for the THC test. An important finding is that the herbal mixture Ngoma Herbal Tonic Immune Booster caused false-negative results for the cannabinoid screening test. It adds to the list of substances that may be potential adulterants of urine for screening tests.

Analytic evaluation of LAMPF II Booster Cavity design

International Nuclear Information System (INIS)

Friedrichs, C.C.

1985-01-01

Through the past few decades, a great deal of sophistication has evolved in the numeric codes used to evaluate electromagnetically resonant structures. The numeric methods are extremely precise, even for complicated geometries, whereas analytic methods require a simple uniform geometry and a simple, known mode configuration if the same precision is to be obtained. The code SUPERFISH, which is near the present state-of-the-art of numeric methods, does have the following limitations: No circumferential geometry variations are permissible; there are no provisions for magnetic or dielectric losses; and finally, it is impractical (because of the complexity of the code) to modify it to extract particular bits of data one might want that are not provided by the code as written. This paper describes how SUPERFISH was used as an aid in derivating an analytic model of the LAMPF II Booster Cavity. Once a satisfactory model was derived, simple FORTRAN codes were generated to provide whatever data was required. The analytic model is made up of TEM- and radial-mode transmission-line sections, as well as lumped elements where appropriate. Radial transmission-line equations, which include losses, were not found in any literature, and the extension of the lossless equations to include magnetic and dielectric losses are included in this paper

Frequency of booster injections of allergoids.

Science.gov (United States)

Norman, P S; Creticos, P S; Marsh, D G

1990-01-01

In 1982, 43 ragweed-sensitive patients receiving maintenance injections of full doses of ragweed allergoid were selected for a study of the immunologic and clinical efficacy of booster injections only four times a year. These patients had participated for 2 to 7 years as part of a trial of mixes of up to four allergoids to common pollens in the mid-Atlantic area tailored to each patient's skin test sensitivity. They were divided into a group (21 patients) to receive injections every 3 months and a group (22 patients) to receive injections about every 6 weeks (eight injections per year). Patients were rerandomized after 1 year so that half of each original group switched to the alternate treatment, and this program was continued until after the ragweed season of 1985. Thirty-four patients were still under study the last year. Doses, per injection, were 100 allergoid units (1 allergoid unit equals 100 PNU) of each allergen in the mixture. Symptom scores during the 8 weeks of each of the four ragweed seasons were not significantly higher in the 3-month treated group. IgG antibody levels to Amb a I (antigen E) were followed until early 1984 and were not significantly different in the two groups, even though the 6-week treated patients received a two times higher cumulative dose per year. Rates of local and systemic reactions (percent of injections eliciting reactions) were not different in the groups, which means that the 3-month treated group had about half as many reactions by virtue of taking half as many injections.(ABSTRACT TRUNCATED AT 250 WORDS)

Development and evaluation of a replicon particle vaccine expressing the E2 glycoprotein of bovine viral diarrhea virus (BVDV in cattle

Directory of Open Access Journals (Sweden)

Loy John Dustin

2013-01-01

Full Text Available Abstract Background Bovine viral diarrhea virus is one of the most significant and costly viral pathogens of cattle worldwide. Alphavirus-derived replicon particles have been shown to be safe and highly effective vaccine vectors against a variety of human and veterinary pathogens. Replicon particles are non-propagating, DIVA compatible, and can induce both humoral and cell mediated immune responses. This is the first experiment to demonstrate that Alphavirus-based replicon particles can be utilized in a standard prime/boost vaccination strategy in calves against a commercially significant bovine pathogen. Findings Replicon particles that express bovine viral diarrhea virus sub-genotype 1b E2 glycoprotein were generated and expression was confirmed in vitro using polyclonal and monoclonal antibodies specific to E2. Vaccine made from particles was generated in Vero cells and administered to BVDV free calves in a prime/boost regimen at two dosage levels. Vaccination resulted in neutralizing antibody titers that cross-neutralized both type 1 and type 2 BVD genotypes following booster vaccination. Additionally, high dose vaccine administration demonstrated some protection from clinical disease and significantly reduced the degree of leukopenia caused by viral infection. Conclusions Replicon particle vaccines administered in a prime/boost regimen expressing BVDV E2 glycoprotein can induce cross-neutralizing titers, reduce leukopenia post challenge, and mitigate clinical disease in calves. This strategy holds promise for a safe and effective vaccine to BVDV.

Status of the first batch of niobium resonator production for the New Delhi booster linac

International Nuclear Information System (INIS)

Potukuchi, P. N.

1999-01-01

This paper reports the status and details of the costs of construction of niobium superconducting resonant cavities for a linear accelerator, presently being built as a booster for the 15 UD tandem Pelletron accelerator at the Nuclear Science Centre, New Delhi. The linear accelerator will have three cryostat modules, each holding eight quarter-wave resonators. Construction of a batch of ten resonators for the linac started at Argonne National Laboratory in May 1997. For production, all fabrication and all electron beam welding is being done through commercial vendors. Details of construction and present status of the project are presented

Energy and environmental performance assessment of R744 booster supermarket refrigeration systems operating in warm climates

DEFF Research Database (Denmark)

Gullo, Paride; Elmegaard, Brian; Cortella, Giovanni

2016-01-01

This paper presents a theoretical comparison among different commercial refrigeration systems in terms of annual energy consumption and environmental impact. Eight configurations were studied: a R744/R134a cascade refrigeration system (baseline), a conventional and an improved R744 booster system...... as on the running modes of a conventional European supermarket. A transition zone, which occurred between sub critical and transcritical operations, was adopted.The results showed that all the enhanced configurations may achieve a comparable energy saving to the one of the baseline in both the selected locations...

Automated design and optimization of flexible booster autopilots via linear programming, volume 1

Science.gov (United States)

Hauser, F. D.

1972-01-01

A nonlinear programming technique was developed for the automated design and optimization of autopilots for large flexible launch vehicles. This technique, which resulted in the COEBRA program, uses the iterative application of linear programming. The method deals directly with the three main requirements of booster autopilot design: to provide (1) good response to guidance commands; (2) response to external disturbances (e.g. wind) to minimize structural bending moment loads and trajectory dispersions; and (3) stability with specified tolerances on the vehicle and flight control system parameters. The method is applicable to very high order systems (30th and greater per flight condition). Examples are provided that demonstrate the successful application of the employed algorithm to the design of autopilots for both single and multiple flight conditions.

Proposal of 99.99%-aluminum/7N01-Aluminum clad beam tube for high energy booster of Superconducting Super Collider

International Nuclear Information System (INIS)

Ishimaru, Hajime

1994-01-01

Proposal of 99.99% pure aluminum/7N01 aluminum alloy clad beam tube for high energy booster in Superconducting Super Collider is described. This aluminum clad beam tube has many good performances, but a eddy current effect is large in superconducting magnet quench collapse. The quench test result for aluminum clad beam tube is basically no problem against magnet quench collapse. (author)

A randomised, double-blind, non-inferiority clinical trial on the safety and immunogenicity of a tetanus, diphtheria and monocomponent acellular pertussis (TdaP) vaccine in comparison to a tetanus and diphtheria (Td) vaccine when given as booster vaccinations to healthy adults

DEFF Research Database (Denmark)

Thierry-Carstensen, Birgit; Jordan, Karina; Uhlving, Hilde Hylland

2012-01-01

Increasing incidence of pertussis in adolescents and adults has stimulated the development of safe and immunogenic acellular pertussis vaccines for booster vaccination of adolescents and adults.......Increasing incidence of pertussis in adolescents and adults has stimulated the development of safe and immunogenic acellular pertussis vaccines for booster vaccination of adolescents and adults....

Linac4, a New Injector for the CERN PS Booster

CERN Document Server

Garoby, R; Gerigk, F; Hanke, K; Lombardi, A; Pasini, M; Rossi, C; Sargsyan, E; Vretenar, M

2006-01-01

The first bottle-neck towards higher beam brightness in the LHC injector chain is due to space charge induced tune spread at injection into the CERN PS Booster (PSB). A new injector called Linac4 is proposed to remove this limitation. Using RF cavities at 352 and 704 MHz, it will replace the present 50 MeV proton Linac2, and deliver a 160 MeV, 40 mA H- beam. The higher injection energy will reduce space charge effects by a factor of 2, and charge exchange will drastically reduce the beam losses at injection. Operation will be simplified and the beam brightness required for the LHC ultimate luminosity should be obtained at PS ejection. Moreover, for the needs of non-LHC physics experiments like ISOLDE, the number of protons per pulse from the PSB will increase by a significant factor. This new linac constitutes an essential component of any of the envisaged LHC upgrade scenarios. It is also designed to become the low energy part of a future 3.5 GeV, multi-megawatt superconducting linac (SPL). The present desig...

Beam tests on a proton linac booster for hadron therapy

CERN Document Server

De Martinis, C; Berra, P; Birattari, C; Calabretta, L; Crandall, K; Giove, D; Masullo, M R; Mauri, M; Rosso, E; Rovelli, A; Serafini, L; Szeless, Balázs; Toet, D Z; Vaccaro, Vittorio G; Weiss, M; Zennaro, R

2002-01-01

LIBO is a 3 GHz modular side-coupled proton linac booster designed to deliver beam energies up to 200 MeV, as required for the therapy of deep seated tumours. The injected beam of 50 to 70 MeV is produced by a cyclotron like those in several hospitals and research institutes. A full-scale prototype of the first module with an input/output energy of 62/74 MeV, respectively, was designed and built in 1999 and 2000. Full power RF tests were carried out successfully at CERN using a test facility at LIL at the end of the year 2000. In order to prove the feasibility of the acceleration process, an experimental setup with this module was installed at the INFN Laboratorio Nazionale del Sud (LNS) in Catania during 2001. The superconducting cyclotron provided the 62 MeV test beam. A compact solid-state RF modulator with a 4 MW klystron, made available by IBA-Scanditronix, was put into operation to power the linac. In this paper the main features of the accelerator are reviewed and the experimental results obtained duri...

Design of a model dipole magnet for the SSC high energy booster

International Nuclear Information System (INIS)

Hassan, N.; Couzens, K.; Dwyer, S.; Jaisle, A.; Jayakumar, R.; Krishnamurthy, S.; Mihelic, R.; Phillips, S.; Puri, R.K.; Sarna, K.

1994-01-01

A superconducting model dipole magnet has been designed to serve as a vehicle in an R ampersand D program to develop a dipole magnet for potential use in the SSC High Energy Booster. The objective has been to use the Brookhaven National Laboratory (BNL) and Fermi National Accelerator Laboratory (FNAL) 50 mm aperture dipole designs to the maximum possible extent for design of a dipole magnet with the same size aperture and a field intensity of 6.67 T. Objectives of this program have also included an evaluation of magnet cross section designs which provides increased margin and includes a field quality iteration on BNL and FNAL dipole designs. The salient parameters of this magnet are listed. In this paper the 2D magnetic and mechanical design of the cold mass in conceptual and detailed form is presented

Review of the scientific results obtained at the research reactor-booster IBR-30 and the Program of investigations at the neutron source IREN

CERN Document Server

Furman, W

2002-01-01

Brief review of the main scientific results obtained at research reactor booster IBR-30 and its predecessor IBR and IBR-1 for the period 1960 - 2001 is presented. The thesis of the scientific program for the upgrade of IBR-30 resonance neutron source IREN are adduced

Low energy booster radio frequency cavity structural analysis

International Nuclear Information System (INIS)

Jones, K.

1994-01-01

The structural design of the Superconducting Super Collider Low Energy Booster (LEB) Radio Frequency (RF) Cavity is very unique. The cavity is made of three different materials which all contribute to its structural strength while at the same time providing a good medium for magnetic properties. Its outer conductor is made of thin walled stainless steel which is later copper plated to reduce the electrical losses. Its tuner housing is made of a fiber reinforced composite laminate, similar to G10, glued to stainless steel plating. The stainless steel of the tuner is slotted to significantly diminish the magnetically-induced eddy currents. The composite laminate is bonded to the stainless steel to restore the structural strength that was lost in slotting. The composite laminate is also a barrier against leakage of the pressurized internal ferrite coolant fluid. The cavity's inner conductor, made of copper and stainless steel, is subjected to high heat loads and must be liquid cooled. The requirements of the Cavity are very stringent and driven primarily by deflection, natural frequency and temperature. Therefore, very intricate finite element analysis was used to complement conventional hand analysis in the design of the cavity. Structural testing of the assembled prototype cavity is planned to demonstrate the compliance of the cavity design to all of its requirements

Low energy booster radio frequency cavity structural analysis

International Nuclear Information System (INIS)

Jones, K.

1993-04-01

The structural design of the Superconducting Super Collider Low Energy Booster (LEB) Radio Frequency (RF) Cavity is very unique. The cavity is made of three different materials which all contribute to its structural strength while at the same time providing a good medium for magnetic properties. Its outer conductor is made of thin walled stainless steel which is later copper plated to reduce the electrical losses. Its tuner housing is made of a fiber reinforced composite laminate, similar to G10, glued to stainless steel plating. The stainless steel of the tuner is slotted to significantly diminish the magnetically-induced eddy currents. The composite laminate is bonded to the stainless steel to restore the structural strength that was lost in slotting. The composite laminate is also a barrier against leakage of the pressurized internal ferrite coolant fluid. The cavity's inner conductor, made of copper and stainless steel, is subjected to high heat loads and must be liquid cooled. The requirements of the Cavity are very stringent and driven primarily by deflection, natural frequency and temperature. Therefore, very intricate finite element analysis was used to complement conventional hand analysis in the design of the cavity. Structural testing of the assembled prototype cavity is planned to demonstrate the compliance of the cavity design to all of its requirements

Integrated Three-Voltage-Booster DC-DC Converter to Achieve High Voltage Gain with Leakage-Energy Recycling for PV or Fuel-Cell Power Systems

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Chih-Lung Shen

2015-09-01

Full Text Available In this paper, an integrated three-voltage-booster DC-DC (direct current to direct current converter is proposed to achieve high voltage gain for renewable-energy generation systems. The proposed converter integrates three voltage-boosters into one power stage, which is composed of an active switch, a coupled-inductor, five diodes, and five capacitors. As compared with conventional high step-up converters, it has a lower component count. In addition, the features of leakage-energy recycling and switching loss reduction can be accomplished for conversion efficiency improvement. While the active switch is turned off, the converter can inherently clamp the voltage across power switch and suppress voltage spikes. Moreover, the reverse-recovery currents of all diodes can be alleviated by leakage inductance. A 200 W prototype operating at 100 kHz switching frequency with 36 V input and 400 V output is implemented to verify the theoretical analysis and to demonstrate the feasibility of the proposed high step-up DC-DC converter.

Advanced exergy analysis of a R744 booster refrigeration system with parallel compression

DEFF Research Database (Denmark)

Gullo, Paride; Elmegaard, Brian; Cortella, Giovanni

2016-01-01

In this paper, the advanced exergy analysis was applied to a R744 booster refrigeration system with parallel compression taking into account the design external temperatures of 25 degrees C and 35 degrees C, as well as the operating conditions of a conventional European supermarket. The global...... efficiencies of all the chosen compressors were extrapolated from some manufactures' data and appropriated optimization procedures of the performance of the investigated solution were implemented.According to the results associated with the conventional exergy evaluation, the gas cooler/condenser, the HS (high...... stage) compressor and the MT (medium temperature) display cabinet exhibited the highest enhancement potential. The further splitting of their corresponding exergy destruction rates into their different parts and the following assessment of the interactions among the components allowed figuring out...

PENGARUH PENAMBAHAN ZAT ADITIF OCTANE BOOSTER X TERHADAP KINERJA DAN EMISI GAS BUANG KENDARAAN SEPEDA MOTOR TIPE ALL NEW CBR150R

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Gusti Yuditia Rahmadian

2017-11-01

Full Text Available Proses pembakaran pada kendaraan bermotor sangat mempengaruhi kinerja mesin secara keseluruhan dan efisiensi pembakaran pada mesin itu sendiri. Zat aditif merupakan bahan yang ditambahkan pada bahan bakar, baik mesin bensin maupun mesin diesel. Zat aditif digunakan sebagai anti knocking akibat pembakaran yang tidak sempurna dan meningkatakan angka oktan untuk bahan bakar bensin. Penelitian ini bertujuan untuk menganalisis pengaruh komposisi penggunaan zat aditif Octane Booster terhadap kinerja mesin motor CBR150R tahun 2014 menggunakan Dyno test, gas analyzer dan tes konsumsi bahan bakar. Berdasarkan eksperimen didapatkan bahwa campuran komposisi OB2 (1 liter pertamax ditambah 3 ml zat aditif Octane Booster membuat daya dan torsi meningkat menjadi 12.54 kW @10500 rpm dan 12.17 Nm @y500 rpm, serta menurunkan kadar CO menjadi 0.08 % Vol, HC menjadi 129 ppm Vol, O2 menjadi 2.68 % Vol dan menaikkan kadar CO2 menjadi 9.82 % Vol dan masih berada di bawah ambang batas dari ketentuan pemerintah. Komposisi tersebut juga menurunkan tingkat konsumsi bahan bakar menjadi 22.73 ,l/km yang membuat kendaraan menjadi lebih irit.

H/sup /minus// injection into the low-energy booster of the SSC

International Nuclear Information System (INIS)

Colton, E.P.; Thiessen, H.A.

1988-01-01

Protons are accumulated into the low-energy booster of the SSC by utilizing H/sup /minus// → H + conversion in a 225- μg/cm 2 carbon stripping foil. Synchronous injection is performed for 26 turns into stationary rf buckets, thereby allowing operation with variable bunch spacing. By injecting the beam offset in x and y we obtain the required rms normalized transverse emittance area of 0.75 π mm-mr. Similarly the required rms longitudinal emittance area of 1.75π /times/ 10/sup /minus/3/ eVs is obtained by injecting single linac micropulses, centered at /phi/ = 0, and dp/p = +0.12%, into each 49.9-MHz rf bucket formed with an rf voltage of 350 kV. The transverse space-charge tune shift is -0.17 for 10 10 protons/bunch accumulated at 600 MeV. 1 ref., 5 figs., 1 tab

Comparing the effect on the AGS longitudinal emittance of gold ions from the BtA stripping foil with and without a Booster Bunch Merge

Energy Technology Data Exchange (ETDEWEB)

Zeno, K. [Brookhaven National Lab. (BNL), Upton, NY (United States)

2017-12-18

The aim of this note to better understand the effect of merging the Gold bunches in the Booster into one on the resulting AGS longitudinal emittance as compared to not merging them. The reason it matters whether they are merged or not is because they pass through a stripping foil in the BtA line. Data was taken last run (Run 17) for the case where the bunches are not merged, and it will be compared with data from cases where the bunches are merged. Previous data from Tandem operation will also be considered. There are two main pieces to this puzzle. The first is the ε growth associated with the energy spread due to ‘energy straggling’ in the BtA stripping foil and the second is the effective ε growth associated with the energy loss that occurs while passing through the foil. Both of these effects depend on whether or not the Booster bunches have been merged into one.

Immunogenicity and Safety of a Booster Injection of DTap-IPV//Hib (Pentaxim) Administered Concomitantly With Tetravalent Dengue Vaccine in Healthy Toddlers 15-18 Months of Age in Mexico: A Randomized Trial.

Science.gov (United States)

Melo, Flor Irene Rodriguez; Morales, José Juan Renteria; De Los Santos, Abiel Homero Mascareñas; Rivas, Enrique; Vigne, Claire; Noriega, Fernando

2017-06-01

The live, attenuated, tetravalent dengue vaccine (CYD-TDV) is licensed in a number of dengue endemic countries for individuals ≥9 years of age. Before the integration of any vaccine into childhood vaccination schedules, a lack of immune interference and acceptable safety when coadministered with other recommended vaccines should be demonstrated. This randomized, multi-center phase III trial was conducted in Mexico. Healthy toddlers (n = 732) received a booster dose of a licensed pentavalent combination vaccine [diphtheria, tetanus, acellular pertussis, inactivated polio vaccine and Haemophilus influenzae type b (DTaP-IPV//Hib)] either concomitantly or sequentially, with the second dose of CYD-TDV administered as a 3-dose schedule. Antibody titers against diphtheria toxoid, tetanus toxoid and pertussis antigens were measured by enzyme-linked immunosorbent assay. Antibodies against poliovirus and dengue serotypes were measured using a plaque reduction neutralization test. Noninferiority was demonstrated for each of the DTaP-IPV//Hib antigens if the lower limit of the 2-sided 95% confidence interval of the difference in seroconversion rates between the 2 groups (CYD-TDV and placebo) was ≥10%. Safety of both vaccines was assessed. Noninferiority in immune response was demonstrated for all DTaP-IPV//Hib antigens. After 3 doses of CYD-TDV, no difference was observed in the immune response for CYD-TDV between groups. There were no safety concerns during the study. Coadministration of the DTaP-IPV//Hib booster vaccine with CYD-TDV has no observed impact on the immunogenicity or safety profile of the DTaP-IPV//Hib booster vaccine. No difference was observed on the CYD-TDV profile when administered concomitantly or sequentially with the DTaP-IPV//Hib booster vaccine.

Monte Carlo modeling and analyses of YALINA- booster subcritical assembly Part II: pulsed neutron source

International Nuclear Information System (INIS)

Talamo, A.; Gohar, M.Y.A.; Rabiti, C.

2008-01-01

One of the most reliable experimental methods for measuring the kinetic parameters of a subcritical assembly is the Sjoestrand method applied to the reaction rate generated from a pulsed neutron source. This study developed a new analytical methodology for characterizing the kinetic parameters of a subcritical assembly using the Sjoestrand method, which allows comparing the analytical and experimental time dependent reaction rates and the reactivity measurements. In this methodology, the reaction rate, detector response, is calculated due to a single neutron pulse using MCNP/MCNPX computer code or any other neutron transport code that explicitly simulates the fission delayed neutrons. The calculation simulates a single neutron pulse over a long time period until the delayed neutron contribution to the reaction is vanished. The obtained reaction rate is superimposed to itself, with respect to the time, to simulate the repeated pulse operation until the asymptotic level of the reaction rate, set by the delayed neutrons, is achieved. The superimposition of the pulse to itself was calculated by a simple C computer program. A parallel version of the C program is used due to the large amount of data being processed, e.g. by the Message Passing Interface (MPI). The new calculation methodology has shown an excellent agreement with the experimental results available from the YALINA-Booster facility of Belarus. The facility has been driven by a Deuterium-Deuterium or Deuterium-Tritium pulsed neutron source and the (n,p) reaction rate has been experimentally measured by a 3 He detector. The MCNP calculation has utilized the weight window and delayed neutron biasing variance reduction techniques since the detector volume is small compared to the assembly volume. Finally, this methodology was used to calculate the IAEA benchmark of the YALINA-Booster experiment

Antimutagenic and antioxidant effects of a South African traditional formulation used as an immune booster

Directory of Open Access Journals (Sweden)

Mlungisi Ngcobo

2016-03-01

Full Text Available The traditional medicines sector in South Africa is still largely unregulated despite legislation aimed at regulating the practice being in place. The HIV and AIDS epidemic has fuelled demand for traditional medicines, with many patients consulting traditional health practitioners who offer different treatments, including herbal immune boosters. This study investigated the mutagenic and antioxidant effects of the widely sold herbal immune booster, uMakhonya®. The Ames test was used for analysis of the genototoxic effects while the adenosine triphosphate (ATP assay was used to evaluate cell cytotoxicity in peripheral blood mononuclear cells (PBMCs and THP-1 monocytes. To evaluate the antioxidant effects the malondialdehyde (MDA quantification, the nitric oxide and 1,1-diphenyl-2-picryl-hydrazyl (DPPH assays were used. UMakhonya® doses of up to 5000 μg/mL were not genotoxic in the Ames test. UMakhonya® was shown to induce dose-dependent cytotoxicity in both PBMCs and THP-1 cells with doses ranging from 500 μg/ mL to 1000 μg/mL, showing significant (p"less than"0.05 toxicity. UMakhonya® was able to significantly (p"less than"0.05 reduce nitrite radicals at 100 μg/mL while lower doses were not effective when compared to samples stimulated by lipopolysaccharide only. Non-cytotoxic doses of uMakhonya® showed significant (p"less than"0.05 lipid peroxide scavenging ability in supernatants while this scavenging ability was considerably reduced intracellularly. In the DPPH assay, when both uMakhonya® and ascorbic acid were reconstituted in buffered saline, the traditional herbal remedy showed better radical scavenging abilities. Therefore further studies on the genotoxicity of uMakhonya®, when metabolically activated, and its antioxidant effects in in-vivo models are warranted.

"Booster" interventions to sustain increases in physical activity in middle-aged adults in deprived urban neighbourhoods: internal pilot and feasibility study

Directory of Open Access Journals (Sweden)

Walters Stephen J

2011-02-01

Full Text Available Abstract Background Systematic reviews have identified a range of brief interventions which increase physical activity in previously sedentary people. A randomised controlled trial is needed to assess whether providing motivational interviewing, three months after giving initial advice, sustains physical activity levels in those who recently became physically active. This paper reports the results of an internal pilot study designed to test the feasibility of the study in terms of recruitment, per protocol delivery of the intervention and retention at three months. Methods Participants were: aged 40-64 years; resident in deprived areas of Sheffield, UK; and, had recently become physically active as a result of using a brief intervention following an invitation from a mass mailout. Interventions: Motivational Interviewing 'boosters' aimed at sustaining change in physical activity status delivered face-to-face or over the telephone compared with no further intervention. Outcomes of the feasibility study: recruitment of 60 participants from mailout of 3,300; retention of 45 participants with 3-month follow-up accelerometry measurements; 70% of those randomised to boosters receiving intervention per protocol. Sample size and power were recalculated using the accelerometry data collected. Results Forty-seven participants were randomised (78% of the feasibility target; 37 participants were retained at three months, 29 with at least four days of accelerometry data (64% of the feasibility target; 79% of those allocated boosters received them per protocol (surpassing the feasibility target. The proposed sample size of 600 was confirmed as appropriate and power is expected to be sufficient to detect a difference between groups. Conclusions The main study will continue with the original recruitment target of 600 participants but to ensure feasibility, it is necessary to increase recruitment and improve the numbers of those followed-up who have evaluable

Immunogenicity and safety of primary and booster vaccination with 2 investigational formulations of diphtheria, tetanus and Haemophilus influenzae type b antigens in a hexavalent DTPa-HBV-IPV/Hib combination vaccine in comparison with the licensed Infanrix hexa

Science.gov (United States)

Vesikari, Timo; Rivera, Luis; Korhonen, Tiina; Ahonen, Anitta; Cheuvart, Brigitte; Hezareh, Marjan; Janssens, Winnie; Mesaros, Narcisa

2017-01-01

ABSTRACT Safety and immunogenicity of 2 investigational formulations of diphtheria, tetanus and Haemophilus influenzae type b antigens of the combined diphtheria-tetanus-acellular pertussis-hepatitis B-inactivated poliomyelitis-Hib vaccine (DTPa-HBV-IPV/Hib) were evaluated in a Primary (NCT01248884) and a Booster vaccination (NCT01453998) study. In the Primary study, 721 healthy infants (randomized 1:1:1) received 3 doses of DTPa-HBV-IPV/Hib formulation A (DATAPa-HBV-IPV/Hib), or B (DBTBPa-HBV-IPV/Hib) or the licensed DTPa-HBV-IPV/Hib vaccine (Infanrix hexa, GSK; control group) at 2, 3, 4 months of age. Infants were planned to receive a booster dose at 12–15 months of age with the same formulation received in the Primary study; however, following high incidence of fever associated with the investigational formulations in the Primary study, the Booster study protocol was amended and all infants yet to receive a booster dose (N = 385) received the licensed vaccine. In the Primary study, non-inferiority of 3-dose vaccination with investigational formulations compared with the licensed vaccine was not demonstrated due to anti-pertactin failing to meet the non-inferiority criterion. Post-primary vaccination, most infants had seroprotective levels of anti-diphtheria (100% of infants), anti-tetanus antigens (100%), against hepatitis B (≥ 97.5% across groups), polyribosyl-ribitol-phosphate (≥ 88.0%) and poliovirus types 1–3 (≥ 90.5%). Seropositivity rates for each pertussis antigen were 100% in all groups. Higher incidence of fever (> 38°C) was reported in infants receiving the investigational formulations (Primary study: 75.0% [A] and 72.1% [B] vs 58.8% [control]; Booster study, before amendment: 49.4% and 46.6% vs 37.4%, respectively). The development of the investigational formulations was not further pursued. PMID:28340322

Monte Carlo analyses of the source multiplication factor of the YALINA booster facility

Energy Technology Data Exchange (ETDEWEB)

Talamo, Alberto; Gohar, Y.; Kondev, F.; Aliberti, Gerardo [Argonne National Laboratory, 9700 South Cass Avenue, Argonne, IL 60439 (United States); Bolshinsky, I. [Idaho National Laboratory, P. O. Box 2528, Idaho Falls, Idaho 83403 (United States); Kiyavitskaya, Hanna; Bournos, Victor; Fokov, Yury; Routkovskaya, Christina; Serafimovich, Ivan [Joint Institute for Power and Nuclear Research-Sosny, National Academy of Sciences, Minsk, acad. Krasin, 99, 220109 (Belarus)

2008-07-01

The multiplication factor of a subcritical assembly is affected by the energy spectrum and spatial distribution of the neutron source. In a critical assembly, neutrons emerge from the fission reactions with an average energy of approx2 MeV; in a deuteron accelerator driven subcritical assembly, neutrons emerge from the fusion target with a fixed energy of 2.45 or 14.1 MeV, from the Deuterium-Deuterium (D-D) and Deuterium-Tritium (D-T) reactions respectively. This study aims at generating accurate neutronics models for the YALINA Booster facility, based on the use of different Monte Carlo neutron transport codes, at defining the facility key physical parameters, and at comparing the neutron multiplication factor for three different neutron sources: fission, D-D and D-T. The calculated values are compared with the experimental results. (authors)

Monte Carlo analyses of the source multiplication factor of the YALINA booster facility

International Nuclear Information System (INIS)

Talamo, Alberto; Gohar, Y.; Kondev, F.; Aliberti, Gerardo; Bolshinsky, I.; Kiyavitskaya, Hanna; Bournos, Victor; Fokov, Yury; Routkovskaya, Christina; Serafimovich, Ivan

2008-01-01

The multiplication factor of a subcritical assembly is affected by the energy spectrum and spatial distribution of the neutron source. In a critical assembly, neutrons emerge from the fission reactions with an average energy of ∼2 MeV; in a deuteron accelerator driven subcritical assembly, neutrons emerge from the fusion target with a fixed energy of 2.45 or 14.1 MeV, from the Deuterium-Deuterium (D-D) and Deuterium-Tritium (D-T) reactions respectively. This study aims at generating accurate neutronics models for the YALINA Booster facility, based on the use of different Monte Carlo neutron transport codes, at defining the facility key physical parameters, and at comparing the neutron multiplication factor for three different neutron sources: fission, D-D and D-T. The calculated values are compared with the experimental results. (authors)

Fabrication of a prototype dipole for the SSC Low Energy Booster

International Nuclear Information System (INIS)

Spencer, C.M.

1993-12-01

The Low Energy Booster of the Superconducting Super Collider (SSC) will be a synchrotron containing 96 dipoles operating between 0.13 T and 1.35 T at 10 Hz. Each dipole's 1.865 m-long core is made from ∼2900 steel laminations (lams), each 52 x 66 cm and 0.635 mm thick. A need to minimize power supply costs and stringent field specifications led to a straight core with very tight mechanical tolerances of the order of 0.05 mm. To satisfy these tolerances, we decided to stack the core in a vertical position; i.e., with the laminations laid horizontally. We designed and built an unusual vertical stacking fixture that pivots into a horizontal position after all the laminations have been stacked and compressed and four support angles welded onto the laminations. The stacking fixture, our experience using it, and conclusions as to the merits of stacking such a long core vertically will be described. The methods of insulating and potting the pancake coils and their installation into the unsplittable core is also described

European project BOOSTER: how to sort victims of a nuclear accident?

International Nuclear Information System (INIS)

Robbe, M.F.; Gmar, M.; Schoepff, V.

2013-01-01

The purpose of the BOOSTER project is to develop tools allowing victims to be sorted quickly according to their level of irradiation. The fastness of the sorting is very important as a nuclear accident or a terrorist attack involving a dirty bomb is likely to cause numerous casualties. A preliminary sorting can be made with a portable walk-through gamma detector that allows the detection of contaminated victims. 4 technologies are proposed for assessing in less than 20 minutes the level of irradiation of a victim: the first method that is based on the analysis of the phosphorylation of the H2AX protein, allows the determination of the irradiation level from the analysis of a drop of blood. The second method allows the determination of the radionuclides present in a drop of blood or urine. The third method uses the thermo-luminescent properties of SMD resistances present in mobile phones to determine the level of irradiation. The fourth method is based on a portable low-background gamma spectrometer able to study environmental and biological samples on the spot. (A.C.)

Prospects for the measurement of muon-neutrino disappearance at the FNAL-Booster

CERN Document Server

Anokhina, A; Benettoni, M; Bernardini, P; Brugnera, R; Calabrese, M; Cecchetti, A; Cecchini, S; Chernyavskiy, M; Creti, P; Corso, F Dal; Dalkarov, O; Del Prete, A; De Robertis, G; De Serio, M; Esposti, L Degli; Di Ferdinando, D; Dusini, S; Dzhatdoev, T; Fanin, C; Fini, R A; Fiore, G; Garfagnini, A; Golovanov, S; Guerzoni, M; Klicek, B; Kose, U; Jakovcic, K; Laurent, G; Lippi, I; Loddo, F; Longhin, A; Malenica, M; Mancarella, G; Mandrioli, G; Margiotta, A; Marsella, G; Mauri, N; Medinaceli, E; Mengucci, A; Mingazheva, R; Morgunova, O; Muciaccia, M T; Nessi, M; Orecchini, D; Paoloni, A; Papadia, G; Paparella, L; Pasqualini, L; Pastore, A; Patrizii, L; Polukhina, N; Pozzato, M; Roda, M; Roganova, T; Rosa, G; Sahnoun, Z; Simone, S; Sirignano, C; Sirri, G; Spurio, M; Stanco, L; Starkov, N; Stipcevic, M; Surdo, A; Tenti, M; Togo, V; Ventura, M; Vladymyrov, M

2014-01-01

Neutrino physics is nowadays receiving more and more attention as a possible source of information for the long-standing problem of new physics beyond the Standard Model. The recent measurement of the mixing angle $\\theta_{13}$ in the standard mixing oscillation scenario encourages us to pursue the still missing results on leptonic CP violation and absolute neutrino masses. However, puzzling measurements exist that deserve an exhaustive evaluation. The NESSiE Collaboration has been setup to undertake conclusive experiments to clarify the muon-neutrino disappearance measurements at small $L/E$, which will be able to put severe constraints to models with more than the three-standard neutrinos, or even to robustly measure the presence of a new kind of neutrino oscillation for the first time. To this aim the use of the current FNAL-Booster neutrino beam for a Short-Baseline experiment has been carefully evaluated. This proposal refers to the use of magnetic spectrometers at two different sites, Near and Far. Thei...

In-flight evaluation of aerodynamic predictions of an air-launched space booster

Science.gov (United States)

Curry, Robert E.; Mendenhall, Michael R.; Moulton, Bryan

1993-01-01

Several analytical aerodynamic design tools that were applied to the Pegasus air-launched space booster were evaluated using flight measurements. The study was limited to existing codes and was conducted with limited computational resources. The flight instrumentation was constrained to have minimal impact on the primary Pegasus missions. Where appropriate, the flight measurements were compared with computational data. Aerodynamic performance and trim data from the first two flights were correlated with predictions. Local measurements in the wing and wing-body interference region were correlated with analytical data. This complex flow region includes the effect of aerothermal heating magnification caused by the presence of a corner vortex and interaction of the wing leading edge shock and fuselage boundary layer. The operation of the first two missions indicates that the aerodynamic design approach for Pegasus was adequate, and data show that acceptable margins were available. Additionally, the correlations provide insight into the capabilities of these analytical tools for more complex vehicles in which design margins may be more stringent.

Booster irradiation to the spleen following total body irradiation. A new immunosuppressive approach for allogeneic bone marrow transplantation

International Nuclear Information System (INIS)

Lapidot, T.; Singer, T.S.; Salomon, O.; Terenzi, A.; Schwartz, E.; Reisner, Y.

1988-01-01

Graft rejection presents a major obstacle for transplantation of T cell-depleted bone marrow in HLA-mismatched patients. In a primate model, after conditioning exactly as for leukemia patients, it was shown that over 99% of the residual host clonable T cells are concentrated in the spleen on day 5 after completion of cytoreduction. We have now corroborated these findings in a mouse model. After 9-Gy total body irradiation (TBI), the total number of Thy-1.2+ cells in the spleen reaches a peak between days 3 and 4 after TBI. The T cell population is composed of both L3T4 (helper) and Lyt-2 (suppressor) T cells, the former being the major subpopulation. Specific booster irradiation to the spleen (5 Gy twice) on days 2 and 4 after TBI greatly enhances production of donor-type chimera after transplantation of T cell-depleted allogeneic bone marrow. Similar enhancement can be achieved by splenectomy on day 3 or 4 after TBI but not if splenectomy is performed 1 day before TBI or 1 day after TBI, strengthening the hypothesis that, after lethal TBI in mice, the remaining host T cells migrate from the periphery to the spleen. These results suggest that a delayed booster irradiation to the spleen may be beneficial as an additional immunosuppressive agent in the conditioning of leukemia patients, in order to reduce the incidence of bone marrow allograft rejection

Parallel bias vs perpendicular bias of a ferrite tuned cavity for the TRIUMF KAON Factory booster ring

International Nuclear Information System (INIS)

Poirier, R.L.; Enegren, T.A.

1988-06-01

The RF cavity reference design for the KAON Factory booster ring is a double gap drift-tube cavity with parallel biased ferrite tuners to vary the frequency from 46 MHz to 62 MHz. LAMPF has developed a single gap cavity with perpendicularly biased ferrite to vary the frequency from 50 MHz to 60 MHz. Measurements on the LAMPF cavity have indicated that their frequency range could be extended to cover our requirements while still maintaining a reasonable magnetic Q. The analysis and comparison of the RF circuit and the AC magnetizing circuit for both designs are reported. (Author) (14 refs., 6 figs.)

Revision of Booster to Storage Ring Transport Line Design and Injection Scheme for Top-Up Operation at NSRRC

CERN Document Server

Wang, Min-Huey; Chen, Jenny; Chen June Rong; Hsu, Kuo-Tung; Kuo, Chin-Cheng; Luo, Gwo-Huei

2005-01-01

In order to help the operation of constant current, the optics of booster to storage ring transport line (BTS) design is reinvestigated. The initial twiss parameters are derived by measurement. The optics of the transport line is readjusted according to the measured initial beam parameters. The design of pulse width of the injection kicker is also changed from 1.2μsecond to 2.0μsecond. The injection scheme is reviewed and the effects of the kicker error on both injected beam and stored beam are investigated and shown in this report.

The B-cell response to a primary and booster course of MenACWY-CRM₁₉₇ vaccine administered at 2, 4 and 12 months of age.

Science.gov (United States)

Blanchard-Rohner, Geraldine; Snape, Matthew D; Kelly, Dominic F; O'Connor, Daniel; John, Tessa; Clutterbuck, Elizabeth A; Ohene-Kena, Brigitte; Klinger, Chaam L; Odrljin, Tatjana; Pollard, Andrew J

2013-05-07

A quadrivalent meningococcal vaccine conjugated to CRM197 (MenACWY-CRM197) is immunogenic in young infants. We assessed the memory B-cell and antibody responses after a primary and booster course of MenACWY-CRM197 in children. At 5 months of age, following primary immunisation, serogroup-specific memory B-cells were detectable in fewer than 25% of children, although protective antibody titres (hSBA ≥ 4) were detectable in 69% of children against serogroup A and more than 95% against the other serogroups. At 12 months, before booster immunisation the percentages with hSBA ≥ 4 were 5% for serogroup A, and between 44 and 70% for the other serogroups. One month after booster immunisation with MenACWY-CRM197 over 50% of children had detectable memory B-cells, and 91% had hSBA ≥ 4 against serogroup A and more than 99% against the other serogroups. These data show that few antigen-specific anticapsular memory B-cells can be detected after two-doses priming with MenACWY-CRM197. For MenC and CRM197, the antigens with the highest number of B-cells at 5 months, there was a definite (p ≤0 .02) but weak correlation with antibody persistence at 12 months. Although previous studies suggest that measuring memory B-cell responses after priming immunisations in infancy can be used to predict antibody persistence and memory responses, this may not be suitable for all antigens in young children. Copyright © 2013 Elsevier Ltd. All rights reserved.

Small scale thermal violence experiments for combined insensitive high explosive and booster materials

Energy Technology Data Exchange (ETDEWEB)

Rae, Philip J [Los Alamos National Laboratory; Bauer, Clare L [AWE, UK; Stennett, C [DCMT SHRIVENHAM, UK; Flower, H M [AWE, UK

2010-01-01

A small scale cook-off experiment has been designed to provide a violence metric for both booster and IHE materials, singly and in combination. The experiment has a simple, axisymmetric geometry provided by a 10 mm internal diameter cylindrical steel confinement up to 80 mm in length. Heating is applied from one end of the sample length creating pseudo 1-D heating profile and a thermal gradient across the sample(s). At the opposite end of the confinement to the heating block, a machined groove provides a point of rupture that generates a cylindrical fragment. The displacement of the external face of the fragment is detected by Heterodyne Velocimetry. Proof of concept experiments are reported focusing on HMX and TATB formulations, and are described in relation to confinement, ullage and heating profile. The development of a violence metric, based upon fragment velocity records is discussed.

Improving the performance of district heating systems by utilization of local heat boosters

DEFF Research Database (Denmark)

Falcone, A.; Dominkovic, D. F.; Pedersen, A. S.

was to evaluate the possibilities to lower the forward temperature of the heat supply in order to reduce the heat losses of the system. Booster heat pumps are introduced to increase the water temperature close to the final users. A Matlab model was developed to simulate the state of the case study DH network...... was set to minimize the system heat losses. * Corresponding author 0303-1 1 This goal was achieved by lowering the forward temperature to 40°C and relying on the installed heat pumps to boost the water temperature to the admissible value needed for the domestic hot water preparation. Depending......District Heating (DH) plays an important role into the Danish energy green transition towards the future sustainable energy systems. The new, 4 th generation district heating network, the so called Low Temperature District Heating (LTDH), tends to lower the supply temperature of the heat down to 40...

Performance of a correlator filter in betatron tune measurements and damping on the NSLS booster

International Nuclear Information System (INIS)

Galayda, J.

1985-01-01

A ''compensated correlator filter'', described by Kramer, et al. has been used for measurement and damping of betatron oscillations in the NSLS booster. The filter consists of a zero-degree power splitter, a 180-degree splitter, a length of 7/8'' air dielectric coaxial cable, and a short length of RG-58 cable. Connected to a beam position monitor, the output of the filter is proportional to the difference in transverse position of each bunch on subsequent turns. The useful bandwidth of the filter for damping rigid bunch oscillations extends from 10 MHz to 250 MHz, in contrast with the gigahertz bandwidth requirements for stochastic cooling, for which the filter was originally proposed. Attenuation of all rotation harmonics in this bandwidth is 40 to 60 dB

Using PHM to measure equipment usable life on the Air Force's next generation reusable space booster

Science.gov (United States)

Blasdel, A.

The U.S. Air Force procures many launch vehicles and launch vehicle services to place their satellites at their desired location in space. The equipment on-board these satellite and launch vehicle often suffer from premature failures that result in the total loss of the satellite or a shortened mission life sometimes requiring the purchase of a replacement satellite and launch vehicle. The Air Force uses its EELV to launch its high priority satellites. Due to a rise in the cost of purchasing a launch using the Air Force's EELV from 72M in 1997 to as high as 475M per launch today, the Air Force is working to replace the EELV with a reusable space booster (RSB). The RSB will be similar in design and operations to the recently cancelled NASA reusable space booster known as the Space Shuttle. If the Air Force uses the same process that procures the EELV and other launch vehicles and satellites, the RSB will also suffer from premature equipment failures thus putting the payloads at a similar high risk of mission failure. The RSB is expected to lower each launch cost by 50% compared to the EELV. The development of the RSB offers the Air Force an opportunity to use a new reliability paradigm that includes a prognostic and health management program and a condition-based maintenance program. These both require using intelligent, decision making self-prognostic equipment The prognostic and health management program and its condition-based maintenance program allows increases in RSB equipment usable life, lower logistics and maintenance costs, while increasing safety and mission assurance. The PHM removes many decisions from personnel that, in the past resulted in catastrophic failures and loss of life. Adding intelligent, decision-making self-prognostic equipment to the RSB will further decrease launch costs while decreasing risk and increasing safety and mission assurance.

Immunogenicity, Safety and Reactogenicity of a Booster Dose of the 10-Valent Pneumococcal Nontypeable H. influenzae Protein D Conjugate Vaccine Coadministered With DTPa-IPV-Hib in Dutch Children: A Randomized Controlled Trial.

Science.gov (United States)

van den Bergh, Menno R; Spijkerman, Judith; François, Nancy; Swinnen, Kristien; Borys, Dorota; Schuerman, Lode; Veenhoven, Reinier H; Sanders, Elisabeth A M

2016-07-01

Immune responses and safety profiles may be affected when vaccines are coadministered. We evaluated the immunogenicity, safety and reactogenicity of a booster dose of the 10-valent pneumococcal nontypeable Haemophilus influenzae protein D-conjugate (PHiD-CV; Synflorix GSK Vaccines) and DTPa-IPV-Hib (Pediacel Sanofi Pasteur MSD) when coadministered. We performed booster assessment in a randomized controlled trial in the Netherlands. Of 780 enrolled healthy infants, 774 toddlers participated in the booster phase and received (1:1:1) (1) PHiD-CV + DTPa-HBV-IPV/Hib (Infanrix hexa, GSK Vaccines), (2) PHiD-CV + DTPa-IPV-Hib, or (3) 7-valent pneumococcal conjugate vaccine (7vCRM, Prevenar/Prevnar, Pfizer, Inc.) + DTPa-IPV-Hib at 2, 3, 4 and 11-13 months old. Blood samples were taken postprimary, prebooster, 1 and 12 months postbooster. Antipneumococcal antibody responses were comparable between both PHiD-CV groups, except for serotype 18C (conjugated to tetanus toxoid). Anti-18C antibody geometric mean concentrations (GMCs) were higher when coadministered with DTPa-HBV-IPV/Hib. For each vaccine serotype, the percentages of children with antibody concentration ≥ 0.20 μg/mL were within the same ranges between PHiD-CV groups (93.8%-100%). The same was observed for the percentages of participants with opsonophagocytic activity titer ≥ 8 (90.9%-100%). When comparing both DTPa-IPV-Hib groups, postbooster antidiphtheria antibody GMCs were higher when coadministered with 7vCRM, while antitetanus and antipolyribosyl-ribitol phosphate antibody GMCs were higher with PHiD-CV coadministration. Regardless, antibody levels to these antigens were well above thresholds. Safety and reactogenicity profiles were comparable between groups. Coadministration of a booster dose of PHiD-CV and DTPa-IPV-Hib was immunogenic and well tolerated.

Vacuum chamber eddy current correction coil for the AGS Booster

International Nuclear Information System (INIS)

Danby, G.; Jackson, J.

1988-01-01

The AGS Booster injector will perform a variety of functions. Heavy ion acceleration requires a bakeable, ultra-high vacuum system (VC). Acceleration for intense proton beams requires rapid cycling (B /preceq/ 10T/sec). If straight forward heavy walled VC are used, the field perturbations due to eddy currents are large. The state of the art lattice has highly distributed lumped sextupoles capable of substantially correcting the induced field nonlinearity. Nevertheless, for the very highest space charge-intensity limits, it is desirable to have the capability to remove eddy current fields at the source. Correction coils attached to the outside of the VC cancel its current aberrations over the required good field aperture. These can be passively powered by transformer action, using two turn windings around the magnet yoke. Programmed power supplies can also be used. This inexpensive additional correction option uses a three turn per quadrant coil which follows the local contour of the VC. Transverse movements of several mms of the VC will have no beam optical effect since the large field aberrations and their corrections have the same displaced coordinates. Experimental and computer studies will be presented, as well as mechanical and electrical design of a simple method of construction. 6 figs

Annular Internal-External-Expansion Rocket Nozzles for Large Booster Applications

Science.gov (United States)

Connors, James F.; Cubbison, Robert W.; Mitchell, Glenn A.

1961-01-01

For large-thrust booster applications, annular rocket nozzles employing both internal and external expansion are investigated. In these nozzles, free-stream air flows through the center as well as around the outside of the exiting jet. Flaps for deflecting the rocket exhaust are incorporated on the external-expansion surface for thrust-vector control. In order to define nozzle off-design performance, thrust vectoring effectiveness, and external stream effects, an experimental investigation was conducted on two annular nozzles with area ratios of 15 and 25 at Mach 0, 2, and 3 in the Lewis 10- by 10-foot wind tunnel. Air, pressurized to 600 pounds per square inch absolute, was used to simulate the exhaust flow. For a nozzle-pressure-ratio range of 40 to 1000, the ratio of actual to ideal thrust was essentially constant at 0.98 for both nozzles. Compared with conventional convergent-divergent configurations on hypothetical boost missions, the performance gains of the annular nozzle could yield significant orbital payload increases (possibly 8 to 17 percent). A single flap on the external-expansion surface of the area-ratio-25 annular nozzle produced a side force equal to 4 percent of the axial force with no measurable loss in axial thrust.

Vacuum chamber eddy current correction coil for the AGS booster

International Nuclear Information System (INIS)

Danby, G.; Jackson, J.

1988-01-01

This paper reports on the AGS Booster injector that performs a variety of functions. Heavy ion acceleration requires a bakeable, ultra-high vacuum system (VC). Acceleration for intense proton beams requires rapid cycling (B ≤10T/sec). If straight forward heavy walled VC are used, the field perturbations due to eddy currents are large. The state of the art lattice has highly distributed lumped sextupoles capable of substantially correcting the induced field nonlinearity. Nevertheless, for the very highest space charge-intensity limits, it is desirable to have the capability to remove eddy current fields at the source. Correction coils attached to the outside of the VC cancel its current aberrations over the required good field aperture. These can be passively powered by transformer action, using two turn windings around the magnet yoke. Programmed power supplies can also be used. This inexpensive additional correction option uses a three turn per quadrant coil which follows the local contour of the VC. Transverse movements of several mms of the VC will have no beam optical effect since the large field aberrations and their corrections have the same displace coordinates. Experimental and computer studies will be presented, as well as mechanical and electrical design of a simple method of construction

A perpendicular AC biased ferrite tuned cavity for the TRIUMF KAON factory booster synchrotron

International Nuclear Information System (INIS)

Poirier, R.L.; Enegren, T.A.; Haddock, C.; Enchevich, I.

1990-06-01

The rf cavity for the booster synchrotron requires a frequency swing of 46 MHz at a repetition rate of 50 Hz. This will be accomplished using a tuner containing yttrium garnet ferrite where the bias field is perpendicular to the rf magnetic field. Conventional methods use parallel biased NiZn ferrite. Yttrium garnet ferrite possess a high electric quality factor. However the ac magnetizing circuit is much more complicated and special care must be taken to minimize the induced eddy current losses when designing the tuner. A dc biased prototype cavity was constructed and tested at Los Alamos. As part of the project definition study for the proposed KAON factory, this cavity has now been almost entirely rebuilt at TRIUMF with a completely redesigned tuner for ac bias operation. Measurements and test results will be reported. (Author) 2 refs., 8 figs

Booster main magnet power supply, present operation and potential future upgrades

Energy Technology Data Exchange (ETDEWEB)

Bajon, E.; Bannon, M.; Marneris, I.; Danowski, G.; Sandberg, J.; Savatteri, S.

2011-03-28

The Brookhaven Booster Main Magnet Power Supply (MMPS) is a 24 pulse thyristor control supply, rated at 5500 Amps, +/-2000 Volts, or 3000 Amps, +/-6000 Volts. The power supply is fed directly from the power utility and the peak magnet power is 18 MWatts. This peak power is seen directly at the incoming ac line. This power supply has been in operation for the last 18 years. This paper will describe the present topology and operation of the power supply, the feedback control system and the different modes of operation of the power supply. Since the power supply has been in operation for the last 18 years, upgrading this power supply is essential. A new power supply topology has been studied where energy is stored in capacitor banks. DC to DC converters are used to convert the dc voltage stored in the capacitor banks to pulsed DC voltage into the magnet load. This enables the average incoming power from the ac line to be constant while the peak magnet power is pulsed to +/- 18 MWatts. Simulations and waveforms of this power supply will be presented.

Immunogenicity and safety of combined adsorbed low-dose diphtheria, tetanus and inactivated poliovirus vaccine (REVAXIS®) versus combined diphtheria, tetanus and inactivated poliovirus vaccine (DT Polio®) given as a booster dose at 6 years of age

Science.gov (United States)

Gajdos, Vincent; Soubeyrand, Benoit; Vidor, Emmanuel; Richard, Patrick; Boyer, Julie; Sadorge, Christine

2011-01-01

This randomized, comparative, phase-IIIb study conducted in France aimed to demonstrate whether seroprotection against diphtheria, tetanus and poliomyelitis 1 month after a single dose of REVAXIS (low-dose diphtheria) is non-inferior to seroprotection 1 month after a single dose of DT Polio (standard-dose diphtheria), both vaccines being given as a second booster to healthy children at 6 years of age. Children were randomly assigned to receive a single intramuscular dose of REVAXIS or DT Polio. Primary endpoints were the 1-month post-booster seroprotection rates for diphtheria, tetanus and poliovirus type-1, -2 and -3 antigens. Secondary endpoints were immunogenicity and safety observations. Of 788 children screened, 760 were randomized: REVAXIS group, 384 children; DT Polio group, 376 children. No relevant difference in demographic characteristics at baseline was observed between REVAXIS and DT Polio groups. Noninferiority of REVAXIS compared with DT Polio for seroprotection was demonstrated against diphtheria (respectively 98.6% and 99.3%), tetanus (respectively 99.6% and 100%) and poliovirus antigens (100% for each types in both groups). No allergic reactions to REVAXIS were reported. A benefit/risk ratio in favor of REVAXIS was suggested by the trend towards a better tolerability of REVAXIS compared with DT Polio regarding the rate of severe solicited injection-site reactions. The results support the use of REVAXIS as a booster at 6 years of age in infants who previously received a three-dose primary series within the first 6 months of life and a first booster including diphtheria, tetanus and poliovirus vaccine(s) given before 2 years of age. PMID:21441781

Design of the New Wideband RF System for the CERN PS Booster

CERN Document Server

Paoluzzi, Mauro; Angoletta, Maria Elena; Arnaudon, Luca; Energico, Salvatore; Findlay, Alan; Haase, Matthias; Jaussi, Michael; Jones, Anthony; Landré, David; Molendijk, John; Quartullo, Danilo; Shaposhnikova, Elena

2016-01-01

For the renovation and upgrade of the CERN PS Booster (PSB) RF systems a development project was launched in 2012. The design, based on a new approach, aimed at replacing the existing tuned, narrowband RF systems with wideband, modular, solid-state driven units. A wide range of issues had to be addressed spanning from RF power production, radiation hardness of solid-state devices, active cancellation of beam-induced voltages, dedicated low-level electronics allowing multi-harmonic operation and beam stability. Following a three-year prototyping and testing campaign and two international reviews, the project endorsement came at the end of year 2015. It foresees the complete removal of present h1, h2 and h10 systems and the deployment of a new one covering all the frequency ranges from 1 MHz to 18 MHz. The four PSB rings will be equipped with 144 identical acceleration cells providing 24 kV total RF voltage per ring. This paper describes the design concepts, the retained solutions, the expected performances and...

Immunogenicity, safety and reactogenicity of a booster dose of the 10-valent pneumococcal Nontypeable H. influenzae Protein D conjugate vaccine coadministered with DTPa-IPV-Hib in Dutch children

NARCIS (Netherlands)

Van Den Bergh, Menno R.; Spijkerman, Judith; François, Nancy; Swinnen, Kristien; Borys, Dorota; Schuerman, Lode; Veenhoven, Reinier H.; Sanders, Elisabeth A M

2016-01-01

Background: Immune responses and safety profiles may be affected when vaccines are coadministered. We evaluated the immunogenicity, safety and reactogenicity of a booster dose of the 10-valent pneumococcal nontypeable Haemophilus influenzae protein D-conjugate (PHiD-CV; Synflorix GSK Vaccines) and

Use of Ni63 Overvoltage Gap Switches in the Flight Termination Systems on Boosters Launched from U.S. Army Kwajalein Atoll (USAKA)

Science.gov (United States)

1990-05-01

COMMAND AGENCY: United States Army Strategic Defense Command. ACTION: Use of Ni63 Overvoltage Gap Switches in the Flight Termination Systems on Boosters...SOURCE OF FUNDING NUMBERS PROGRAM PROJECT TASK WORK UNIT ELEMENT NO. NO. NO. ACCESSION NO. I TITLE (Include Security Claification) Use of Ni63 ...U) 1 PERSONAL AUTHOR(S) Ni63 Environmental Assessment Team, Mr. Randy Gallien (Chairman) 1𔄁. TYPE OF REPORT 13b. TIME COVERED 14. DATE OF REPORT

Preparation and characterisation of polymeric lamellar substrate particles (PLSP)

International Nuclear Information System (INIS)

Khairullah, Noor Hasnah Mohamed

2002-01-01

Polymer microparticles have tremendous potential as the next generation of adjuvant systems to replace the only adjuvant currently widely registered for human use, alum. Based on aluminium salts, alum adjuvants work as short-term depots of adsorbed protein/antigens that slowly 'leak' into the body's immune system, inducing immunity by invoking a humoral response. The main disadvantage of alum adjuvants is that they do not raise sufficient antibody levels to induce long-term immunity. Hence, booster administrations are required. This drawback presents the biggest factor in the failure of many vaccination programmes. Polymer microparticulate systems can be fashioned to deliver sub-unit and peptide antigens in a continuous or controlled rate over a desired period of time, avoiding the need for booster doses. The design of mucosal vaccines is now centred upon the use of these polymeric carriers. The mucosal route for immunisation has many advantages over the more conventional systemic route, the most important of which, is the induction of both humoral and cellular immunity. Polymer microspheres of sizes <10μm are especially good candidates as oral vaccine adjuvants as they are taken up by the M cells of the Peyer's patches in the intestine. Numerous studies have been carried out on microspheres into which antigens have been encapsulated or entrapped. There are, however, problems associated with loss of antigenicity since formulation procedures involve the use of organic solvents and harsh shearing methods. Additionally, these antigens may be further degraded when the polymer material itself degrades in vivo and produces acidic species. A novel adjuvant system that avoids the above problems is currently being evaluated. Poly(l-lactide) (PLLA) polymeric lamellar substrate particles (PLSP) are promising as novel adjuvants for the controlled release of antigens. Reports have shown that the adsorption of antigens onto the surface of these particles can induce cellular

[Postdoctoral lecturer thesis in medicine: academic competence or career booster?].

Science.gov (United States)

Sorg, H; Betzler, C; Grieswald, C; Schwab, C G G; Tilkorn, D J; Hauser, J

2016-06-01

The postdoctoral lecturer thesis in medicine represents an essential success factor for the career of a physician; however, there is controversial discussion on whether this reflects academic competence or is more a career booster. In this context we conducted a survey among postdoctoral medical lecturers with the aim to evaluate the significance of this qualification. The online survey was performed using a questionnaire requesting biographical parameters and subjective ratings of topics concerning the postdoctoral lecturer thesis. Overall 628 questionnaires were included in the study. The significance of the postdoctoral qualification was rated high in 68.6 % and was seen to be necessary for professional advancement in 71.0 %. The chances of obtaining a full professorship after achieving a postdoctoral qualification were rated moderate to low (68.1 %); nevertheless, 92.3 % would do it again and 86.5 % would recommend it to colleagues. Accordingly, 78.8 % were against its abolishment. Wishes for reforms included standardized federal regulations, reduced dependency on professors and more transparency. The postdoctoral lecturer qualification in medicine is highly valued and the majority of responders did not want it to be abolished. Although the chances for a full professorship were only rated low, successful graduation seems to be beneficial for the career; however, there is a need for substantial structural and international changes.

3 GeV Booster Synchrotron Conceptual Design Report

Energy Technology Data Exchange (ETDEWEB)

Wiedemann, Helmut

2009-06-02

Synchrotron light cna be produced from a relativistic particle beam circulating in a storage ring at extremely high intensity and brilliance over a large spectral region reaching from the far infrared regime to hard x-rays. The particles, either electrons or positrons, radiate as they are deflected in the fields of the storage ring bending magnets or of magnets specially optimized for the production of synchrotron light. The synchrotron light being very intense and well collimated in the forward direction has become a major tool in a large variety of research fields in physics, chemistry, material science, biology, and medicine.

Structural and thermal analysis of a solid-cooled, low energy booster, radio-frequency-cavity tuner at the Superconducting Super Collider

International Nuclear Information System (INIS)

Ranganathan, R.; Propp, A.; Dao, B.; Campbell, B.

1993-04-01

A three-dimensional heat conduction and structural model was developed to analyze and optimize the design of a solid-cooled low energy booster (LEB) radio-frequency (RF) cavity tuner concept. Consideration was given to three cooling options: (1) using beryllium oxide (BeO) disks, (2) using aluminum nitride (A1N) disks and (3) using neither BeO nor AlN disks. The results indicate that solid cooling is feasible from thermal and structural viewpoints if a minimum of two BeO disks or four AlN disks are used

Structural and thermal analysis of a solid-cooled, low energy booster, radio-frequency-cavity tuner at the Superconducting Super Collider

Energy Technology Data Exchange (ETDEWEB)

Ranganathan, R.; Propp, A.; Dao, B.; Campbell, B.

1993-04-01

A three-dimensional heat conduction and structural model was developed to analyze and optimize the design of a solid-cooled low energy booster (LEB) radio-frequency (RF) cavity tuner concept. Consideration was given to three cooling options: (1) using beryllium oxide (BeO) disks, (2) using aluminum nitride (A1N) disks and (3) using neither BeO nor AlN disks. The results indicate that solid cooling is feasible from thermal and structural viewpoints if a minimum of two BeO disks or four AlN disks are used.

Search for Muon Neutrino Disappearance in the Booster Neutrino Beam of Fermilab; Busqueda de Desaparicion de Neutrinos del Muon en el Haz de Neutrinos del Booster de Fermilab

Energy Technology Data Exchange (ETDEWEB)

Mendez Mendez, Diana Patricia [Univ. Nacional Autonoma de Mexico (UNAM), Mexico City (Mexico)

2015-01-01

In this work we carried out the disappearance analysis of muon neutrinos produced in the Fermilab Booster Neutrino Beam, using the data released to the public by the collaborations of the MiniBooNE and SciBooNE experiments. The calculations were made with programs in C and C++, implementing the ROOT libraries. From the analysis, using both the classical Pearson method and the Feldman and Cousins frequentist corrections, we obtained the 90\\% C.L. limit for the oscillation parameters sin²2θ and Δm² in the region 0.1 ≤ Δm² ≤ 10 eV² using a two neutrino model. The result presented in this work is consistent with the official one, with small deviations ascribed to round-off errors in the format of the used data, as well as statistical fluctuations in the generation of fake experiments used in the Feldman and Cousins method. As the official one, our result is consistent with the null oscillation hypothesis. This work was carried out independently to the MiniBooNE and SciBooNE collaborations and its results are not official.

Assessment of immunogenicity and safety following primary and booster immunisation with a CRM197 -conjugated Haemophilus influenzae type B vaccine in healthy Chinese infants.

Science.gov (United States)

Jun, L; Yuguo, C; Zhiguo, W; Jinfeng, L; Huawei, M; Xiuhua, L; Yonggui, Z; Yanhua, X; Kong, Y; Hongtao, L; Yuliang, Z

2013-10-01

Invasive meningitis and pneumonia caused by Haemophilus influenzae type b (Hib) is an important cause of childhood mortality in countries where Hib vaccination is not routine. We evaluated the non-inferiority of a licensed Hib vaccine, PRP-CRM(197) compared with a second licensed Hib vaccine, PRP-T, following the recommended Chinese immunisation schedule for infants between 6 months and 1 year of age. In the first study phase, 6-12 month-old infants received two primary doses of either PRP-CRM(197) (n = 335) or PRP-T (n = 335) vaccine administered 1 month apart. In the second study phase 8 months later, the same children received a single booster dose of vaccine identical to that use for priming (PRP-CRM(197), n = 327; PRP-T, n = 333). Serum levels of anti-polyribosylribitol phosphate (PRP) antibodies were measured using enzyme-linked immunosorbent assay (ELISA). Non-inferiority of primary and booster doses was assessed in terms of percentages of subjects with anti-PRP antibody levels associated with providing short-term (≥ 0.15 μg/ml) and long-term (≥ 1.0 μg/ml) protection; the non-inferiority margin was set at -5%. PRP-CRM(197) was demonstrated to be non-inferior to PRP-T. Anti-PRP antibodies levels ≥ 0.15 μg/ml and ≥ 1.0 μg/ml were achieved by 97% of infants in the PRP-CRM(197) group and 98% of infants in the PRP-T group 1 month after primary immunisation, and by all subjects (100%) in both vaccine groups 1 month after booster administration. Safety profiles for both vaccines were similar; no serious adverse events, deaths or adverse events leading to withdrawal occurred during the study. PRP-CRM(197) was well-tolerated and immunologically non-inferior to a licensed comparator Hib vaccine in Chinese infants (Clinicaltrials.gov: NCT01044316 & NCT01226953). © 2013 John Wiley & Sons Ltd.

A neutron booster for spallation sources--application to accelerator driven systems and isotope production

CERN Document Server

Galy, J; Van Dam, H; Valko, J

2002-01-01

One can design a critical system with fissile material in the form of a thin layer on the inner surface of a cylindrical neutron moderator such as graphite or beryllium. Recently, we have investigated the properties of critical and near critical systems based on the use of thin actinide layers of uranium, plutonium and americium. The thickness of the required fissile layer depends on the type of fissile material, its concentration in the layer and on the geometrical arrangement, but is typically in the mu m-mm range. The resulting total mass of fissile material can be as low as 100 g. Thin fissile layers have a variety of applications in nuclear technology--for example in the design neutron amplifiers for medical applications and 'fast' islands in thermal reactors for waste incineration. In the present paper, we investigate the properties of a neutron booster unit for spallation sources and isotope production. In those applications a layer of fissile material surrounds the spallation source. Such a module cou...

Innovative Comparison of Transient Ignition Temperature at the Booster Interface, New Stainless Steel Pyrovalve Primer Chamber Assembly "V" (PCA) Design Versus the Current Aluminum "Y" PCA Design

Science.gov (United States)

Saulsberry, Regor L.; McDougle, Stephen H.; Garcia,Roberto; Johnson, Kenneth L.; Sipes, William; Rickman, Steven; Hosangadi, Ashvin

2011-01-01

An assessment of four spacecraft pyrovalve anomalies that occurred during ground testing was conducted by the NASA Engineering & Safety Center (NESC) in 2008. In all four cases, a common aluminum (Al) primer chamber assembly (PCA) was used with dual NASA Standard Initiators (NSIs) and the nearly simultaneous (separated by less than 80 microseconds) firing of both initiators failed to ignite the booster charge. The results of the assessment and associated test program were reported in AIAA Paper AIAA-2008-4798, NESC Independent Assessment of Pyrovalve Ground Test Anomalies. As a result of the four Al PCA anomalies, and the test results and findings of the NESC assessment, the Mars Science Laboratory (MSL) project team decided to make changes to the PCA. The material for the PCA body was changed from aluminum (Al) to stainless steel (SS) to avoid melting, distortion, and potential leakage of the NSI flow passages when the device functioned. The flow passages, which were interconnected in a Y-shaped configuration (Y-PCA) in the original design, were changed to a V-shaped configuration (V-PCA). The V-shape was used to more efficiently transfer energy from the NSIs to the booster. Development and qualification testing of the new design clearly demonstrated faster booster ignition times compared to the legacy AL Y-PCA design. However, the final NESC assessment report recommended that the SS V-PCA be experimentally characterized and quantitatively compared to the Al Y-PCA design. This data was deemed important for properly evaluating the design options for future NASA projects. This test program has successfully quantified the improvement of the SS V-PCA over the Al Y-PCA. A phase B of the project was also conducted and evaluated the effect of firing command skew and enlargement of flame channels to further assist spacecraft applications.

Sensitive screening of abused drugs in dried blood samples using ultra-high-performance liquid chromatography-ion booster-quadrupole time-of-flight mass spectrometry.

Science.gov (United States)

Chepyala, Divyabharathi; Tsai, I-Lin; Liao, Hsiao-Wei; Chen, Guan-Yuan; Chao, Hsi-Chun; Kuo, Ching-Hua

2017-03-31

An increased rate of drug abuse is a major social problem worldwide. The dried blood spot (DBS) sampling technique offers many advantages over using urine or whole blood sampling techniques. This study developed a simple and efficient ultra-high-performance liquid chromatography-ion booster-quadrupole time-of-flight mass spectrometry (UHPLC-IB-QTOF-MS) method for the analysis of abused drugs and their metabolites using DBS. Fifty-seven compounds covering the most commonly abused drugs, including amphetamines, opioids, cocaine, benzodiazepines, barbiturates, and many other new and emerging abused drugs, were selected as the target analytes of this study. An 80% acetonitrile solvent with a 5-min extraction by Geno grinder was used for sample extraction. A Poroshell column was used to provide efficient separation, and under optimal conditions, the analytical times were 15 and 5min in positive and negative ionization modes, respectively. Ionization parameters of both electrospray ionization source and ion booster (IB) source containing an extra heated zone were optimized to achieve the best ionization efficiency of the investigated abused drugs. In spite of their structural diversity, most of the abused drugs showed an enhanced mass response with the high temperature ionization from an extra heated zone of IB source. Compared to electrospray ionization, the ion booster (IB) greatly improved the detection sensitivity for 86% of the analytes by 1.5-14-fold and allowed the developed method to detect trace amounts of compounds on the DBS cards. The validation results showed that the coefficients of variation of intra-day and inter-day precision in terms of the signal intensity were lower than 19.65%. The extraction recovery of all analytes was between 67.21 and 115.14%. The limits of detection of all analytes were between 0.2 and 35.7ngmL -1 . The stability study indicated that 7% of compounds showed poor stability (below 50%) on the DBS cards after 6 months of storage at

Results of Preliminary Tests of PAR Bunch Cleaning

CERN Document Server

Yao, Chihyuan; Grelick, Arthur; Lumpkin, Alex H; Sereno, Nicholas S

2005-01-01

A particle accumulator ring (PAR) is used at the Advanced Photon Source (APS) to collect multiple linac bunches and compress them into a 0.3-ns (rms) single bunch for booster injection. A 9.77-MHz fundamental rf system and a 117.3-MHz harmonic rf system are employed for initial beam capture and bunch length compression. Satellite bunches with very low charge form due to rf phase drifts or beam loading change. These satellites, when injected into the booster and then into the storage ring (SR), cause bunch impurity at three buckets from the target bucket. Storage ring and booster bunch cleaning was tried but proved to be difficult due to the top-up mode of operation in the storage ring and tune drift in the booster synchrotron. Recently we implemented a PAR bunch-cleaning system with tune-modulated harmonic rf knockout. Preliminary tests gave a measured SR bunch purity of better than 10

H/sup /minus// injection into the low-energy booster of the SSC [Superconducting Super Collider

International Nuclear Information System (INIS)

Colton, E.P.; Thiessen, H.A.

1989-01-01

Protons are accumulated into the low-energy booster of the SSC by utilizing H/sup /minus// → H + conversion in a 225-μg/cm 2 carbon stripping foil. Synchronous injection is performed for 26 turns into stationary rf buckets, thereby allowing operation with variable bunch spacing. By injecting the beam offset in x and y we obtain the required rms normalized transverse emittance area of 0.75 π mm-mr. Similarly the required rms longitudinal emittance area of 1.75π /times/ 10/sup /minus/3/ eVs is obtained by injecting single linac micropulses, centered at /phi/ = 0, and dp/p = +0.12%, into each 49.9-MHz rf bucket formed with an rf voltage of 350 kV. The transverse space-charge tune shift is /minus/0.17 for 10 10 protons/bunch accumulated at 600 MeV. 1 ref., 5 figs., 1 tab

Particle size distribution control of Pt particles used for particle gun

Science.gov (United States)

Ichiji, M.; Akiba, H.; Nagao, H.; Hirasawa, I.

2017-07-01

The purpose of this study is particle size distribution (PSD) control of submicron sized Pt particles used for particle gun. In this report, simple reaction crystallization is conducted by mixing H2PtCl6 and ascorbic acid. Without the additive, obtained Pt particles have broad PSD and reproducibility of experiment is low. With seeding, Pt particles have narrow PSD and reproducibility improved. Additionally, mean particle diameter of 100-700 nm is controlled by changing seeding amount. Obtained particles are successfully characterized as Pt by XRD results. Moreover, XRD spectra indicate that obtained particles are polycrystals. These experimental results suggest that seeding consumed nucleation, as most nuclei attached on the seed surface. This mechanism virtually restricted nucleation to have narrow PSD can be obtained.

Performance of the AC perpendicular biased ferrite tuned cavity for the TRIUMF KAON factory booster synchrotron

International Nuclear Information System (INIS)

Poirier, R.L.; Enchevich, I.B.; Mitra, A.K.; Fong, K.; Blaker, G.C.; Fang, S.

1992-11-01

The rf cavity for the Booster Synchrotron requires a frequency swing from 46 Mhz to 61 Mhz at a repetition rate of 50 Hz and a maximum accelerating voltage of 62.5 kV. These requirements were achieved on the prototype ferrite tuned cavity[1] for a short period of time and without any fast rf feedback or cavity tuning loops. Initially fast rf feedback and cavity tuning loops were closed at fixed frequencies (ferrite tuner dc biased ) to measure some of the response characteristics of the amplifier-cavity chain. Then a major effort was put into measuring the bandwidth response of the tuner in order to design the rf control loops for ac bias operation at 50 Hz. The performance of these control loops and results from long term running of the rf system are reported. (author) 3 refs., 5 figs

Leukocyte transcript alterations in West-African girls following a booster vaccination with diphtheria-tetanus-pertussis vaccine

DEFF Research Database (Denmark)

Orntoft, Nikolaj W; Thorsen, Kasper; Benn, Christine S

2013-01-01

identified a group of nine comparable West African girls, from a biobank of 356 children, who were due to receive DTP booster vaccine at age 18 months. As a pilot experiment we extracted RNA from blood samples before, and 6 weeks after, vaccination to analyze the coding transcriptome in leukocytes using......Background. Observational studies from low-income countries have shown that the vaccination against diphtheria, tetanus and pertussis (DTP) is associated with excess female mortality due to infectious diseases. Methods. To investigate possible changes in gene expression after DTP vaccination, we...... expression microarrays, and ended up with information from eight girls. The data was further analyzed using dedicated array pathway and network software. We aimed to study whether DTP vaccination introduced a systematic alteration in the immune system in girls. Results. We found very few transcripts to alter...

Dynamic aperture ampersand extraction studies for the SSC High-Energy Booster

International Nuclear Information System (INIS)

Chao, A.W.; Dutt, S.K.; Johnson, D.E.; Sen, T.; Yan, Y.

1990-09-01

The final booster in the injector chain for the Superconducting Super Collider is a machine approximately twice the size of the Tevatron. Its design includes approximately 450, 15+ m superconducting dipoles. The original designs specified dipoles with a 7 cm coil-winding diameter and an inner horizontal beam-pipe aperture of 55 mm. This dipole design was chosen in order to provide an adequately large good-field aperture for both the beam injection process and for the slow-extraction of high-energy test beams. With the recent decision to increase the Collider dipole coil-winding diameter to 5 cm, the question of the needed HEB aperture was raised. An argument for dipole commonality between the HEB and Collider was developed, and a preliminary examination of a 5 cm HEB dipole was undertaken. This paper reports the results of a detailed study of the injection dynamic aperture for magnet errors corresponding to both a 5 cm and 7 cm dipole. Also studied and reported are preliminary results of the resonant-extraction process for the two magnet designs in question. These studies are in the form of multiparticle computer simulations. The results of the studies indicate that the 7 cm dipole design is consistent with the desired performance requirements for the HEB, while the 5 cm dipole design is marginal. We have not studied intermediate aperture values. 8 refs., 11 figs

Power test for first prototype LIBO module

CERN Multimedia

Laurent Guiraud

2000-01-01

The Linac Booster (LIBO) is a prototype machine for producing particle beams for cancer therapy. Hadron therapy techniques are able to reach deep tumours with less damage to surrounding tissue than with conventional radiotherapy.

PENTACLE: Parallelized particle-particle particle-tree code for planet formation

Science.gov (United States)

Iwasawa, Masaki; Oshino, Shoichi; Fujii, Michiko S.; Hori, Yasunori

2017-10-01

We have newly developed a parallelized particle-particle particle-tree code for planet formation, PENTACLE, which is a parallelized hybrid N-body integrator executed on a CPU-based (super)computer. PENTACLE uses a fourth-order Hermite algorithm to calculate gravitational interactions between particles within a cut-off radius and a Barnes-Hut tree method for gravity from particles beyond. It also implements an open-source library designed for full automatic parallelization of particle simulations, FDPS (Framework for Developing Particle Simulator), to parallelize a Barnes-Hut tree algorithm for a memory-distributed supercomputer. These allow us to handle 1-10 million particles in a high-resolution N-body simulation on CPU clusters for collisional dynamics, including physical collisions in a planetesimal disc. In this paper, we show the performance and the accuracy of PENTACLE in terms of \\tilde{R}_cut and a time-step Δt. It turns out that the accuracy of a hybrid N-body simulation is controlled through Δ t / \\tilde{R}_cut and Δ t / \\tilde{R}_cut ˜ 0.1 is necessary to simulate accurately the accretion process of a planet for ≥106 yr. For all those interested in large-scale particle simulations, PENTACLE, customized for planet formation, will be freely available from https://github.com/PENTACLE-Team/PENTACLE under the MIT licence.

AC bias operation of the perpendicular biased ferrite tuned cavity for the TRIUMF KAON Factory booster synchrotron

International Nuclear Information System (INIS)

Poirier, R.L.; Enegren, T.A.; Enchevich, I.B.

1991-05-01

The RF cavity for the booster synchrotron requires a frequency swing from 46 MHz at a repetition rate of 50 Hz and a maximum accelerating gap voltage of 65 kV. A DC biased prototype cavity built at LANL using perpendicular-biased yttrium-garnet ferrites, rather than the more conventional parallel-biased NiZn ferrites, has now undergone major reconstruction at TRIUMF for AC bias operation. RF signal level measurements have shown that the frequency swing at a repetition rate of 50 Hz can be accomplished and still handle the eddy current losses in the cavity structures with minimal effect on the magnetizing field. The prototype cavity is now undergoing high power RF tests with full power AC bias operation. The results of these tests and operational experience is reported. (Author) ref., 6 figs

Stress Corrosion Cracking and Fatigue Crack Growth Studies Pertinent to Spacecraft and Booster Pressure Vessels

Science.gov (United States)

Hall, L. R.; Finger, R. W.

1972-01-01

This experimental program was divided into two parts. The first part evaluated stress corrosion cracking in 2219-T87 aluminum and 5Al-2.5Sn (ELI) titanium alloy plate and weld metal. Both uniform height double cantilever beam and surface flawed specimens were tested in environments normally encountered during the fabrication and operation of pressure vessels in spacecraft and booster systems. The second part studied compatibility of material-environment combinations suitable for high energy upper stage propulsion systems. Surface flawed specimens having thicknesses representative of minimum gage fuel and oxidizer tanks were tested. Titanium alloys 5Al-2.5Sn (ELI), 6Al-4V annealed, and 6Al-4V STA were tested in both liquid and gaseous methane. Aluminum alloy 2219 in the T87 and T6E46 condition was tested in fluorine, a fluorine-oxygen mixture, and methane. Results were evaluated using modified linear elastic fracture mechanics parameters.

Energy-signal quality trade-offs in a WiMAX mobile station with a booster amplifier

Science.gov (United States)

Suherman; Mubarakah, N.; Wiranata, O.; Kasim, S. T.

2018-02-01

Worldwide Interoperability for Microwave Access (WiMAX) is a broadband wireless access technology that is able to provide high bit rate mobile internet services. Battery endurance remains a problem in current mobile communication. On the other hand, signal quality determines the successful run of the mobile applications. Energy consumption optimization cannot sacrifice the signal level required by the application to run smoothly. On the contrary, the application should consider battery life time. This paper examines the tradeoffs between energy and signal quality in WiMAX subscriber station by adjusting signal level using a booster amplifier. Simulation evaluations show that an increment of 0.00000104% energy consumption on using amplifier adaptively produces 16.411% signal to noise ratio (SNR) increment and 10.7% bit error rate (BER) decrement. By keeping the amplifier turned on, energy consumption increases up to 0.00000136%, causing the SNR rises to 17.2638% and BER drops to 11.13%. The evaluated application is video streaming, other application may behave differently.

Structural optimization of an alternate design for the Space Shuttle solid rocket booster field joint

Science.gov (United States)

Barthelemy, Jean-Francois M.; Rogers, James L., Jr.; Chang, Kwan J.

1987-01-01

A structural optimization procedure is used to determine the shape of an alternate design for the Shuttle's solid rocket booster field joint. In contrast to the tang and clevis design of the existing joint, this alternate design consists of two flanges bolted together. Configurations with 150 studs of 1 1/8 in diameter and 135 studs of 1 3/16 in diameter are considered. Using a nonlinear programming procedure, the joint weight is minimized under constraints on either von Mises or maximum normal stresses, joint opening and geometry. The procedure solves the design problem by replacing it by a sequence of approximate (convex) subproblems; the pattern of contact between the joint halves is determined every few cycles by a nonlinear displacement analysis. The minimum weight design has 135 studs of 1 3/16 in diameter and is designed under constraints on normal stresses. It weighs 1144 lb per joint more than the current tang and clevis design.

Structural and mechanical design challenges of space shuttle solid rocket boosters separation and recovery subsystems

Science.gov (United States)

Woodis, W. R.; Runkle, R. E.

1985-01-01

The design of the space shuttle solid rocket booster (SRB) subsystems for reuse posed some unique and challenging design considerations. The separation of the SRBs from the cluster (orbiter and external tank) at 150,000 ft when the orbiter engines are running at full thrust meant the two SRBs had to have positive separation forces pushing them away. At the same instant, the large attachments that had reacted launch loads of 7.5 million pounds thrust had to be servered. These design considerations dictated the design requirements for the pyrotechnics and separation rocket motors. The recovery and reuse of the two SRBs meant they had to be safely lowered to the ocean, remain afloat, and be owed back to shore. In general, both the pyrotechnic and recovery subsystems have met or exceeded design requirements. In twelve vehicles, there has only been one instance where the pyrotechnic system has failed to function properly.

AC magnetic measurements of the ALS Booster Synchrotron Dipole Magnet engineering model

International Nuclear Information System (INIS)

Green, M.I.; Hoyer, E.; Keller, R.; Nelson, D.H.

1988-09-01

We made a minimal set of AC magnetic measurements of the engineering model of the ALS Booster Dipole Magnet as part of the process of qualifying its design for production. Magnetic induction integrals over paths approximating electron-beam trajectories were measured with long curved coils connected to an electronic integrator. Magnetic induction was measured with point coils and an integrator and independently with a Hall-effect Gaussmeter. These quantities, and magnet current, were displayed on a commercial digital storage oscilloscope as parametric functions of time. The displayed waveforms were stored, processed and redisplayed as representations of selected magnet parameters. A waveform representing the magnet's effective-length was created by dividing the integral waveform by the magnetic induction waveform. Waveforms of the transfer functions were produced by dividing both the integral waveform and the magnetic induction waveform by the current waveform. Pairs of matched coils, connected in series opposition, provided differential measurements of field uniformity. Quadrupole and sextupole coefficients were derived from the uniformity data. These magnet parameters were measured at 2 and 10 Hz frequencies. Together with measurements of the magnetic field at selected dc levels, the ac measurements demonstrated that the magnet design met specifications and qualified it for production. 7 refs., 7 figs., 3 tabs

Advocacy for booster seat legislation in Florida: a lesson in politics and policy formation.

Science.gov (United States)

Haring, R Sterling; Frattaroli, Shannon; Schneider, Eric B; Holland, M Becker; Vernick, Jon S

2015-04-01

MVCs are a major contributor to child injury and death. Infant restraint seats and child booster seats have been shown to reduce the odds of severe injury or death when used correctly. While all states have mandated the use of these restraint systems, the age at which a child can be legally restrained using an adult seat belt varies from state to state. Efforts to strengthen Florida's weak child restraint laws have failed for more than a decade; in the 2014 legislative session, advocates succeeded in raising the state's age requirement from 3 years to 5  years. While many factors contributed to this year's success, some key elements included efficient communication of supporting data, a strong and broad advocacy network and the leveraging of election year political rivalries. Efforts to further strengthen the law will continue into future legislative sessions. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Upgrade of the CERN Proton Synchrotron Booster bending magnets for 2 GeV Operation

CERN Document Server

Newborough, A; Chritin, R

2013-01-01

Since its first operation in 1972 at an energy of 800MeV the CERN Proton Synchrotron Booster, which consists of 4 super imposed synchrotrons, has seen two upgrades: once to 1.0 GeV in 1988 and then to 1.4 GeV in 1999. During this time the main magnets of the machine have remained largely unchanged with small differences (<1%) between the inner and outer gaps of the main bending magnet fields being compensated by trim power supplies. The future upgrade of the machine will demand to extract protons at an energy of 2.0 GeV and require almost double the original dipole field. At this field, due to saturation effects, the inner and outer gaps of the main dipole magnets will differ by up to 4%. This paper presents the design and implementation of a modification of the magnetic circuit strongly reducing these effects. We also discuss the results of experimental tests concerning the effects on field quality and eddy current transients, including the implications for the real-time magnetic field measurement system ...

Fracture tolerance analysis of the solid rocket booster servo-actuator for the space shuttle

Energy Technology Data Exchange (ETDEWEB)

Smith, S.H.; Ghadiali, N.D.; Zahoor, A.; Wilson, M.R.

1982-01-01

The results of an evaluation of the fracture tolerance of three components of the thrust vector control servo-actuator for the solid rocket booster of the space shuttle are described. These components were considered as being potentially fracture critical and therefore having the potential to fall short of a desired service life of 80 missions (that is, a service life factor of 4.0 on a basic service life of 20 missions). Detailed stress analysis of the rod end, cylinder, and feedback link components was accomplished by three-dimensional finite-element stress analysis methods. A dynamic structural model of the feedback system was used to determine the dynamic inertia loads and reactions to apply to the finite-element model of the feedback link. Twenty mission stress spectra consisting of lift-off, boost, re-entry, and water impact mission segments were developed for each component based on dynamic loadings. Most components were determined to have the potential of reaching a service life of 80 missions or service life factor of 4.0. 22 refs.

Lack of effect of a booster dose of influenza vaccine in hemodialysis patients.

Science.gov (United States)

Tanzi, Elisabetta; Amendola, Antonella; Pariani, Elena; Zappa, Alessandra; Colzani, Daniela; Logias, Franco; Perego, Angelo; Zanetti, Alessandro R

2007-08-01

To assess whether the administration of a booster dose of influenza vaccine may enhance immune response in hemodialysis patients, 58 subjects were given two doses of the 2003/2004 season influenza vaccine, 1 month apart. "European Agency for the Evaluation of Medicinal Products" (EMEA) criteria were fully met in terms of percentage of response and of mean-fold increase of hemagglutination inhibiting (HI) antibody titer, but not in terms of seroprotection rates (HI antibody titers > or =1:40). The second vaccine administration did not result in additional increase in seroprotection rate or in geometric mean titers. Protective immune response against the epidemic A/H3N2 Fujian-like strain, antigenically distant from that included in the vaccine (A/Panama/2007/99) was observed in 94.7% of vaccinees protected against the A/H3N2 vaccine strain 1 month after immunization. No adverse reactions were reported during follow-up. The study findings suggest that immune response to influenza vaccination may be suboptimal in hemodialysis patients and that the administration of an additional second dose of vaccine does not improve the humoral response.

Safety aspects of pulsed YAYOI and Japan Linac Booster

International Nuclear Information System (INIS)

An, S.; Oka, Y.; Wakabayashi, J.

1976-01-01

The paper consists of two parts. The first part is concerned with safety aspects of pulsed YAYOI. Reactivity pulsed operation of YAYOI is performed with reactivity oscillating devices. Inherent safety characteristics due to dilation of metal fuel, a small amount of f.p. build up, reactor operation preserving fuel integrity and experience on transient experiments are the principal basis for safety assurance. Conditions for pulsed operation, namely, maximum allowable temperature, maximum number of repetition of pulsed operation and so on are derived from the consideration on the integrity of fuel. Instrumentation and control systems are reinforced by displacement meter in the core, interlock system, special timer for pulsed operation, additional scram conditions and reactivity meter. Accident analysis and safety evaluation indicate the conservative safety features of the facility. Concerning pulsed operation of YAYOI combined with Linac, special attention must be given to the design of Linac target placed in the core. In the second part are described the principal guide-lines and basic ideas for safety design of Japan Linac Booster (JLB). JLB is a U-Mo fueled and sodium cooled fast reactor with rotating reflector and Linac target in the core. The pulsed neutrons are injected into the core coincidentally with repetitive peaks of reactivity. Design of rotating reflector and Linac target system are the new and important safety problems not yet encountered in the usual sodium fast reactor design. The axis of the rotating reflector is horizontal, which avoids the collision of reflector block with core in the case of failure of rotating reflector. The separate cooling channels for target and the Linac electron beam control system are provided. Reactor shut down and power control systems must be carefully designed. Core meltdown and disassembly accident is considered as a hypothetical accident which is a basis for containment system design. (auth.)

Vacuum Chamber for the Booster Bending Magnets

CERN Multimedia

CERN PhotoLab

1974-01-01

To minimise eddy currents, induced by the rising magnetic field, the chamber was made from thin stainless steel of high specific electric resistance. For mechanical strength, it was corrugated in a hydro-forming process. The cross-section was designed for maximum strength and maximum aperture. To accept particles with simultaneous large amplitudes in both planes, the cross-section approaches a rectangular shape (see also 7402463).

Use of a booster dose of capsular group C meningococcal glycoconjugate vaccine to demonstrate immunologic memory in children primed with one or two vaccine doses in infancy.

Science.gov (United States)

Pace, David; Khatami, Ameneh; Attard-Montalto, Simon; Voysey, Merryn; Finn, Adam; Faust, Saul N; Heath, Paul T; Borrow, Ray; Snape, Matthew D; Pollard, Andrew J

2016-12-07

Use of a polysaccharide vaccine challenge to demonstrate immunologic memory after priming with capsular group C meningococcal conjugate vaccines (MenCC) risks induction of immunologic hyporesponsiveness. For this reason, MenCC vaccines are now used as probes of immunologic memory, however, no studies have demonstrated their ability to distinguish primed from unprimed children. This study was part of a randomised controlled trial investigating the immunogenicity of a booster dose of the combined Haemophilus influenzae type b and MenC-tetanus toxoid vaccine (Hib-MenC-TT) in infants receiving reduced dose MenCC vaccine priming schedules (one MenC-CRM/MenC-TT or two MenC-CRM vaccine doses) compared with an unprimed group. Antibody kinetics were studied in a subset of 269 children by measuring changes in the MenC serum bactericidal antibody, using rabbit complement, (MenC rSBA) titres and MenC specific IgG memory B-cells before and at 6 and 28days following the 12month booster vaccination. At 6days after the 12monthMenCC vaccine, the rise in MenC rSBA titres and MenC specific IgG memory B-cells of the primed groups were significantly higher than the infant MenCC naïve group. Participants primed with one MenC-TT dose had the highest increase in MenC rSBA titres compared with all other groups. The MenC rSBA titres at the 28th compared with the 6th day after boosting was significantly higher in those primed with a single MenC-TT/MenC-CRM vaccine in infancy compared with those who were not primed or who were primed with two doses of the MenC-CRM vaccine. Immunologic memory can be demonstrated by a MenCC booster vaccination but is affected by the type and number of MenCC doses used for infant priming. The MenC rSBA responses can be used to demonstrate successful immunologic priming. Copyright © 2016 Elsevier Ltd. All rights reserved.

Beam tests of ionization chambers for the NuMI neutrino beam

Energy Technology Data Exchange (ETDEWEB)

Robert M. Zwaska et al.

2003-09-25

We have conducted tests at the Fermilab Booster of ionization chambers to be used as monitors of the NuMI neutrino beamline. The chambers were exposed to proton fluxes of up to 10{sup 12} particles/cm{sup 2}/1.56 {micro}s. We studied space charge effects which can reduce signal collection from the chambers at large charged particle beam intensities.

Evolution of High Intensity Beams in the CERN PS Booster after H⁻ Injection and Phase Space Painting

CERN Document Server

Cieslak-Kowalska, Magdalena; Benedetto, Elena; Bracco, Chiara

2016-01-01

With the LHC Injector Upgrade (LIU) project, the injection energy of PS Booster (PSB) ' first circular accelerator in the LHC injector chain ' will be raised from 50 MeV to 160 MeV and the present multiturn injection will be upgraded to H⁻ injection with transverse and longitudinal painting. In the scope of this project, it is planned to double the beam intensities, profiting from the fact that the βγ2 factor will be two times larger (0.35 at 50 MeV and 0.71 at 160 MeV), so the resulting tune spread driven by a direct space charge should remain similar. This paper describes the feasibility to double the intensity of high intensity and large emittance beams, looking into the evolution under space charge and taking into account losses constrains in the ring and in the extraction lines.

Report of the third seminar on nuclear physics at the energy region of the JAERI tandem-booster accelerator February 27-28, 1992, Tokai, Japan

International Nuclear Information System (INIS)

Iwamoto, Akira; Oshima, Masumi; Ikezoe, Hiroshi; Nagame, Yuichiro; Shinohara, Nobuo

1992-09-01

A seminar on new experiments to be studied and new experimental apparatus suitable for the JAERI tandem-booster accelerator being under construction was held at Tokai Research Establishment of JAERI in the period from February 27 to 28, 1992. Sixty eight participants from universities and from JAERI attended to discuss the following items: 1. Physics at low temperature, 2. Nuclear structure at high spin and at high excitation energy, 3. Application of unstable beam and their spectroscopy, 4. Nuclear reaction at intermediate energy, 5. New facilities. (author)

Particle-two particle interaction in configuration space

International Nuclear Information System (INIS)

Kuzmichev, V.E.

1982-07-01

The problem if three indentical particles with zero-range two-particle interaction is considered. An explicit expression for the effective potential between one particle and the remaining two-particle system is obtained in the coordinate representation. It is shown that for arbitrary energies, at small and, for zero energy, at large distances rho between the one particle and centre of mass of the other two particles the diagonal matrix element of the effective potential is attractive and proportional to 1/rho 2 . This property of the effective potenial explains both the Thomas singularity and the Efimov effect. In the case of zero total energy of the system the general form of the solution of the three-particle integral equation is found in configuration space. (orig.)

Immunogenicity of a 2-dose priming and booster vaccination with the 10-valent pneumococcal nontypeable Haemophilus influenzae protein D conjugate vaccine

DEFF Research Database (Denmark)

Silfverdal, Sven Arne; Høgh, Birthe; Bergsaker, Marianne Riise

2009-01-01

BACKGROUND: The immunogenicity of the 10-valent pneumococcal nontypeable Haemophilus influenzae protein D-conjugate vaccine (PHiD-CV) was determined following a simplified 2-dose priming and the more commonly employed 3-dose priming both followed by a booster dose. METHODS: A total of 351 healthy....... RESULTS: Depending on the serotype, the percentages of subjects reaching the ELISA antibody threshold of 0.2 microg/mL were 92.8% to 98.0% following 2 primary doses and 96.1% to 100% following 3 primary doses except for serotype 6B (55.7% and 63.1%, respectively) and serotype 23F (69.3% and 77...

Fracture Toughness, Mechanical Property, And Chemical Characterization Of A Critical Modification To The NASA SLS Solid Booster Internal Material System

Science.gov (United States)

Pancoast, Justin; Garrett, William; Moe, Gulia

2015-01-01

A modified propellant-liner-insulation (PLI) bondline in the Space Launch System (SLS) solid rocket booster required characterization for flight certification. The chemical changes to the PLI bondline and the required additional processing have been correlated to mechanical responses of the materials across the bondline. Mechanical properties testing and analyses included fracture toughness, tensile, and shear tests. Chemical properties testing and analyses included Fourier transform infrared (FTIR) spectroscopy, cross-link density, high-performance liquid chromatography (HPLC), gas chromatography (GC), gel permeation chromatography (GPC), and wave dispersion X-ray fluorescence (WDXRF). The testing identified the presence of the expected new materials and found the functional bondline performance of the new PLI system was not significantly changed from the old system.

Assessment of TBT and organic booster biocide contamination in seawater from coastal areas of South Korea.

Science.gov (United States)

Kim, Nam Sook; Shim, Won Joon; Yim, Un Hyuk; Hong, Sang Hee; Ha, Sung Yong; Han, Gi Myung; Shin, Kyung-Hoon

2014-01-15

Seawater samples from major enclosed bays, fishing ports, and harbors of Korea were analyzed to determine levels of tributyltin (TBT) and booster biocides, which are antifouling agents used as alternatives to TBT. TBT levels were in the range of not detected (nd) to 23.9 ng Sn/L. Diuron and Irgarol 1051, at concentration ranges of 35-1360 ng/L and nd to 14 ng/L, respectively, were the most common alternative biocides present in seawater, with the highest concentrations detected in fishing ports. Hot spots were identified where TBT levels exceeded environmental quality targets even 6 years after a total ban on its use in Korea. Diuron exceeded the UK environmental quality standard (EQS) value in 73% of the fishing port samples, 64% of the major bays, and 42% of the harbors. Irgarol 1051 levels were marginally below the Dutch and UK EQS values at all sites. Copyright © 2013 Elsevier Ltd. All rights reserved.