WorldWideScience

Sample records for partial covalent character

  1. Holistic Approach to Partial Covalent Interactions in Protein Structure Prediction and Design with Rosetta.

    Science.gov (United States)

    Combs, Steven A; Mueller, Benjamin K; Meiler, Jens

    2018-05-29

    Partial covalent interactions (PCIs) in proteins, which include hydrogen bonds, salt bridges, cation-π, and π-π interactions, contribute to thermodynamic stability and facilitate interactions with other biomolecules. Several score functions have been developed within the Rosetta protein modeling framework that identify and evaluate these PCIs through analyzing the geometry between participating atoms. However, we hypothesize that PCIs can be unified through a simplified electron orbital representation. To test this hypothesis, we have introduced orbital based chemical descriptors for PCIs into Rosetta, called the PCI score function. Optimal geometries for the PCIs are derived from a statistical analysis of high-quality protein structures obtained from the Protein Data Bank (PDB), and the relative orientation of electron deficient hydrogen atoms and electron-rich lone pair or π orbitals are evaluated. We demonstrate that nativelike geometries of hydrogen bonds, salt bridges, cation-π, and π-π interactions are recapitulated during minimization of protein conformation. The packing density of tested protein structures increased from the standard score function from 0.62 to 0.64, closer to the native value of 0.70. Overall, rotamer recovery improved when using the PCI score function (75%) as compared to the standard Rosetta score function (74%). The PCI score function represents an improvement over the standard Rosetta score function for protein model scoring; in addition, it provides a platform for future directions in the analysis of small molecule to protein interactions, which depend on partial covalent interactions.

  2. Tunability of Open-Shell Character, Charge Asymmetry, and Third-Order Nonlinear Optical Properties of Covalently Linked (Hetero)Phenalenyl Dimers.

    Science.gov (United States)

    Minamida, Yuka; Kishi, Ryohei; Fukuda, Kotaro; Matsui, Hiroshi; Takamuku, Shota; Yamane, Masaki; Tonami, Takayoshi; Nakano, Masayoshi

    2018-02-06

    Tunability of the open-shell character, charge asymmetry, and third-order nonlinear optical (NLO) properties of covalently linked (hetero)phenalenyl dimers are investigated by using the density functional theory method. By changing the molecular species X and substitution position (i, j) for the linker part, a variety of intermonomer distances R and relative alignments between the phenalenyl dimers can be realized from the geometry optimizations, resulting in a wide-range tuning of diradical character y and charge asymmetry. It is found that the static second hyperpolarizabilities along the stacking direction, γ yyyy , are one-order enhanced for phenalenyl dimer systems exhibiting intermediate y, a feature that is in good agreement with the "y-γ correlation". By replacing the central carbon atoms of the phenalenyl rings with a boron or a nitrogen, we have also designed covalently linked heterophenalenyl dimers. The introduction of such a charge asymmetry to the open-shell systems, which leads to closed-shell ionic ground states, is found to further enhance the γ yyyy values of the systems having longer intermonomer distance R with intermediate ionic character, that is, charge asymmetry. The present results demonstrate a promising potential of covalently linked NLO dimers with intermediate open-shell/ionic characters as a new building block of highly efficient NLO systems. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  3. Trapping and partial characterization of an adduct postulated to be the covalent catalytic ternary complex of thymidylate synthetase

    International Nuclear Information System (INIS)

    Ahmed, F.; Moore, M.A.; Dunlap, R.B.

    1986-01-01

    The proposed mechanism of action of thymidylate synthetase envisages the formation of a covalent ternary complex of the enzyme via the active site cysteine with dUMP and 5,10-methylenetetrahydrofolate (CH 2 H 4 folate). The authors recent success in using trichloroacetic acid to trap the covalent enzyme-FdUMP binary and ternary (enzyme-FdUMP-CH 2 H 4 folate) complexes led to the use of this technique in attempts to trap the transient covalent catalytic ternary complex. Experiments performed with [2-C 14 ]dUMP and 3 H-CH 2 H 4 folate show that both these ligands remained bound to the enzyme after trichloroacetic acid precipitation. The trapped covalent catalytic ternary complex was subjected to CNBr fragmentation, and the peptides were fractionated by HPLC. The isolated active-site peptide was shown to retain the two ligands and was subjected to a limited sequence analysis by the dansyl-Edman procedure. The inhibitory ternary complex formed with 14 C-FdUMP and 3 H-CH 2 4 folate served as a control. The active-site peptides isolated from the CNBr treated inhibitory ternary complex and the catalytic complex exhibited identical sequences for the first four N-terminal residues, Ala-Leu-Pro-Pro, and the fifth residue was found to be associated with the labeled ligands. Sequence analysis of the active site peptide derived from the carboxymethylated enzyme confirmed this sequence and the 5th residue was shown to be Cm-Cys

  4. Trapping and partial characterization of an adduct postulated to be the covalent catalytic ternary complex of thymidylate synthetase

    Energy Technology Data Exchange (ETDEWEB)

    Ahmed, F.; Moore, M.A.; Dunlap, R.B.

    1986-05-01

    The proposed mechanism of action of thymidylate synthetase envisages the formation of a covalent ternary complex of the enzyme via the active site cysteine with dUMP and 5,10-methylenetetrahydrofolate (CH/sub 2/H/sub 4/folate). The authors recent success in using trichloroacetic acid to trap the covalent enzyme-FdUMP binary and ternary (enzyme-FdUMP-CH/sub 2/H/sub 4/folate) complexes led to the use of this technique in attempts to trap the transient covalent catalytic ternary complex. Experiments performed with (2-C/sup 14/)dUMP and /sup 3/H-CH/sub 2/H/sub 4/folate show that both these ligands remained bound to the enzyme after trichloroacetic acid precipitation. The trapped covalent catalytic ternary complex was subjected to CNBr fragmentation, and the peptides were fractionated by HPLC. The isolated active-site peptide was shown to retain the two ligands and was subjected to a limited sequence analysis by the dansyl-Edman procedure. The inhibitory ternary complex formed with /sup 14/C-FdUMP and /sup 3/H-CH/sub 2/ /sub 4/folate served as a control. The active-site peptides isolated from the CNBr treated inhibitory ternary complex and the catalytic complex exhibited identical sequences for the first four N-terminal residues, Ala-Leu-Pro-Pro, and the fifth residue was found to be associated with the labeled ligands. Sequence analysis of the active site peptide derived from the carboxymethylated enzyme confirmed this sequence and the 5th residue was shown to be Cm-Cys.

  5. The effect of exposure duration on visual character identification in single, whole and partial report

    DEFF Research Database (Denmark)

    Petersen, Anders; Andersen, Tobias

    2012-01-01

    , all of these having a temporal offset included, as well as the ex-Gaussian, the log-logistic and finally the squared-logistic, which is a psychometric function we believe have not been described before. The log-logistic and the squared-logistic psychometric function fit well to experimental data....... Finally, after insertion into Bundesen’s Theory of Visual Attention (Bundesen, 1990), the same psychometric functions enable closer fits to data from a previous whole and partial report experiment....

  6. Covalent Organic

    DEFF Research Database (Denmark)

    Vutti, Surendra

    chemistry of silicon, InAs and GaAs materials, covalentsurface functionalization using organosilanes, liquid-phase, and vapor-phasefunctionalizations, diazo-transfer reaction, CuAAC click chemistry, different types ofbiorthogonal chemistries, SPAAC chemistry, and cellular interactions of chemically...... immobilization of D-amino acid adhesion peptideson azide functionalized silicon, GaAs and InAs materials by using CuAAC-click chemistry.The covalent immobilization of penetration peptide (TAT) on gold nanotips of InAs NWs isalso demonstrated.In chapter four, the covalent immobilization of GFP on silicon wafers......, GaAs wafers andGaAs NWs is demonstrated. Series of Fmoc-Pra-OH, NHS-PEG5-NHS and BCN-NHSfunctionalized silicon surfaces has been prepared, whereby GFP-N3 and GFP-bicyclononyneare immobilized by using CuAAC and SPAAC chemistry. The specific and covalentimmobilization of GFP-N3 on bicyclononyne...

  7. Electron population uncertainty and atomic covalency

    International Nuclear Information System (INIS)

    Chesnut, D.B.

    2006-01-01

    The atoms-in-molecules (AIM) index of atomic covalency is directly related to the AIM atomic population uncertainty. The covalent bond order, delocalization index, and, therefore, the atomic covalency are maximal when electron pairs are equally shared by the atoms involved. When polarization effects are present, these measures of covalent bond character decrease. We present atomic covalences for the single- and double-heavy atom hydrides of elements of the first and second low rows of the periodic table to illustrate these effects. Some usual behavior is seen in hydrogen-bridged species due in some cases to stronger than expected multicenter bonds and in other cases to many atoms contributing to the covalency index

  8. N,O6-partially acetylated chitosan nanoparticles hydrophobically-modified for controlled release of steroids and vitamin E

    DEFF Research Database (Denmark)

    Quinones, Javier Perez; Gothelf, Kurt Vesterager; Kjems, Jørgen

    2013-01-01

    Diosgenin, two synthetic analogs of brassinosteroids, testosterone and dl-α-tocopherol were covalently linked to synthetic water-soluble N,O6-partially acetylated chitosan, for their controlled release. Drug linking was confirmed by FTIR spectroscopy and proton NMR. Conjugates were also character......Diosgenin, two synthetic analogs of brassinosteroids, testosterone and dl-α-tocopherol were covalently linked to synthetic water-soluble N,O6-partially acetylated chitosan, for their controlled release. Drug linking was confirmed by FTIR spectroscopy and proton NMR. Conjugates were also...

  9. Dislocations in materials with mixed covalent and metallic bonding

    International Nuclear Information System (INIS)

    Nguyen-Manh, D.; Cawkwell, M.J.; Groeger, R.; Mrovec, M.; Porizek, R.; Pettifor, D.G.; Vitek, V.

    2005-01-01

    Environment-dependent bond-order potentials have been developed for L1 0 TiAl, bcc Mo and fcc Ir. They comprise both the angular character of bonding and the screening effect of nearly free electrons. These potentials have been employed in atomistic studies of screw dislocations that revealed the non-planar character of their cores. It is argued that both covalent as well as metallic character of bonding govern these structures, which in turn control the mechanical behaviour

  10. Study on immobilization enzyme using radiation grafting and condensation covalent

    International Nuclear Information System (INIS)

    Cao Jin; Su Zongxian; Gao Jianfeng

    1989-01-01

    The immobilization of gluecose oxidase (GOD) on polyethylene and F 46 is described by radiation grafting and condensation covalent. The GOD on polyethylene film is characterized with IR-spectrum. The results show that the enzyme activity on F 46 film is high when dose rate and covalent yield are low. When covalent yield is 4.3% the enzyme relative activity achieves the greatest value for F 46 film. The experiment also demonstrates that acrylic acid affects the relative activity of enzyme and the method of IR-pectrum character is convenient and efficient for GOD on polyethylene film

  11. Character & Cane

    Science.gov (United States)

    Sartorius, Tara Cady

    2009-01-01

    They say first impressions can be deceiving. The difficulty of getting to know someone increases when that person is mostly fictional. Whatever the author writes is all readers can know. Whatever they read about the character is all they have to go on. Now take it another step back, and imagine a portrait drawing, painting or print of that…

  12. Believable Characters

    Science.gov (United States)

    El-Nasr, Magy Seif; Bishko, Leslie; Zammitto, Veronica; Nixon, Michael; Vasiliakos, Athanasios V.; Wei, Huaxin

    The interactive entertainment industry is one of the fastest growing industries in the world. In 1996, the U.S. entertainment software industry reported 2.6 billion in sales revenue, this figure has more than tripled in 2007 yielding 9.5 billion in revenues [1]. In addition, gamers, the target market for interactive entertainment products, are now reaching beyond the traditional 8-34 year old male to include women, Hispanics, and African Americans [2]. This trend has been observed in several markets, including Japan, China, Korea, and India, who has just published their first international AAA title (defined as high quality games with high budget), a 3D third person action game: Ghajini - The Game [3]. The topic of believable characters is becoming a central issue when designing and developing games for today's game industry. While narrative and character were considered secondary to game mechanics, games are currently evolving to integrate characters, narrative, and drama as part of their design. One can see this pattern through the emergence of games like Assassin's Creed (published by Ubisoft 2008), Hotel Dusk (published by Nintendo 2007), and Prince of Persia series (published by Ubisoft), which emphasized character and narrative as part of their design.

  13. Route Generation for a Synthetic Character (BOT) Using a Partial or Incomplete Knowledge Route Generation Algorithm in UT2004 Virtual Environment

    Science.gov (United States)

    Hanold, Gregg T.; Hanold, David T.

    2010-01-01

    This paper presents a new Route Generation Algorithm that accurately and realistically represents human route planning and navigation for Military Operations in Urban Terrain (MOUT). The accuracy of this algorithm in representing human behavior is measured using the Unreal Tournament(Trademark) 2004 (UT2004) Game Engine to provide the simulation environment in which the differences between the routes taken by the human player and those of a Synthetic Agent (BOT) executing the A-star algorithm and the new Route Generation Algorithm can be compared. The new Route Generation Algorithm computes the BOT route based on partial or incomplete knowledge received from the UT2004 game engine during game play. To allow BOT navigation to occur continuously throughout the game play with incomplete knowledge of the terrain, a spatial network model of the UT2004 MOUT terrain is captured and stored in an Oracle 11 9 Spatial Data Object (SOO). The SOO allows a partial data query to be executed to generate continuous route updates based on the terrain knowledge, and stored dynamic BOT, Player and environmental parameters returned by the query. The partial data query permits the dynamic adjustment of the planned routes by the Route Generation Algorithm based on the current state of the environment during a simulation. The dynamic nature of this algorithm more accurately allows the BOT to mimic the routes taken by the human executing under the same conditions thereby improving the realism of the BOT in a MOUT simulation environment.

  14. Evidence of significant covalent bonding in Au(CN)(2)(-).

    Science.gov (United States)

    Wang, Xue-Bin; Wang, Yi-Lei; Yang, Jie; Xing, Xiao-Peng; Li, Jun; Wang, Lai-Sheng

    2009-11-18

    The Au(CN)(2)(-) ion is the most stable Au compound known for centuries, yet a detailed understanding of its chemical bonding is still lacking. Here we report direct experimental evidence of significant covalent bonding character in the Au-C bonds in Au(CN)(2)(-) using photoelectron spectroscopy and comparisons with its lighter congeners, Ag(CN)(2)(-) and Cu(CN)(2)(-). Vibrational progressions in the Au-C stretching mode were observed for all detachment transitions for Au(CN)(2)(-), in contrast to the atomic-like transitions for Cu(CN)(2)(-), revealing the Au-C covalent bonding character. In addition, rich electronic structural information was obtained for Au(CN)(2)(-) by employing 118 nm detachment photons. Density functional theory and high-level ab initio calculations were carried out to understand the photoelectron spectra and obtain insight into the nature of the chemical bonding in the M(CN)(2)(-) complexes. Significant covalent character in the Au-C bonding due to the strong relativistic effects was revealed in Au(CN)(2)(-), consistent with its high stability.

  15. Characters with personality!

    NARCIS (Netherlands)

    Bosch, K. van den; Brandenburgh, A.; Muller, T.J.; Heuvelink, A.

    2012-01-01

    Serious games offer an opportunity for learning communication skills by practicing conversations with one or more virtual characters, provided that the character(s) behave in accordance with their assigned properties and strate-gies. This paper presents an approach for developing virtual characters

  16. Covalent and non-covalent functionalization and solubilization of ...

    Indian Academy of Sciences (India)

    Wintec

    photographs of the dispersions of amide-functio- nalized DWNTs in dichloromethane and tetrahydro- furan. In figure 3b, we show a TEM image of DWNTs after covalent functionalization. The images are not as sharp after functionalization as in the case of pris- tine nanotubes (figure 3a), and the bundles seem to be intact.

  17. Coexistence of monatomic and diatomic molecular fluid character in liquid gallium

    Energy Technology Data Exchange (ETDEWEB)

    Gong, X.G. (International Centre for Theoretical Physics (ICTP), Trieste (Italy)); Chiarotti, G.L. (International School for Advanced Studies (SISSA), Trieste (Italy) Lab. Tecnologie Avanzate Superfici e Catalisi (TASC), Consorzio Interuniv. Nazionale per la Fisica della Materia (INFM), Trieste (Italy)); Parrinello, M. (IBM Research Div., Zurich Forschungslab., Rueschlikon (Switzerland) International School for Advanced Studies (SISSA), Trieste (Italy)); Tosatti, E. (International School for Advanced Studies (SISSA), Trieste (Italy) International Centre for Theoretical Physics (ICTP), Trieste (Italy) IBM Research Div., Zurich Forschungslab., Rueschlikon (Switzerland))

    1993-02-01

    We have performed an ab initio molecular-dynamics simulation of liquid Ga at high temperature (1000 K). Our results are in good agreement with scattering data and with Knight-shift experiments. A remarkable feature of our findings is the coexistence in the liquid state of metallic and covalent characters. Covalency manifests itself in the appearance of very short-lived Ga-Ga bonds, which represent remnants in the liquid of the crystalline form [alpha]-Ga. We set up a two-fluid scheme which can be used for the analysis of fluids where metallic and covalent characters coexist. (orig.).

  18. Coexistence of monatomic and diatomic molecular fluid character in liquid gallium

    International Nuclear Information System (INIS)

    Gong, X.G.; Chiarotti, G.L.; Parrinello, M.; Tosatti, E.

    1993-01-01

    We have performed an ab initio molecular-dynamics simulation of liquid Ga at high temperature (1000 K). Our results are in good agreement with scattering data and with Knight-shift experiments. A remarkable feature of our findings is the coexistence in the liquid state of metallic and covalent characters. Covalency manifests itself in the appearance of very short-lived Ga-Ga bonds, which represent remnants in the liquid of the crystalline form α-Ga. We set up a two-fluid scheme which can be used for the analysis of fluids where metallic and covalent characters coexist. (orig.)

  19. Hydrogels Based on Dynamic Covalent and Non Covalent Bonds: A Chemistry Perspective

    Directory of Open Access Journals (Sweden)

    Francesco Picchioni

    2018-03-01

    Full Text Available Hydrogels based on reversible covalent bonds represent an attractive topic for research at both academic and industrial level. While the concept of reversible covalent bonds dates back a few decades, novel developments continue to appear in the general research area of gels and especially hydrogels. The reversible character of the bonds, when translated at the general level of the polymeric network, allows reversible interaction with substrates as well as responsiveness to variety of external stimuli (e.g., self-healing. These represent crucial characteristics in applications such as drug delivery and, more generally, in the biomedical world. Furthermore, the several possible choices that can be made in terms of reversible interactions generate an almost endless number of possibilities in terms of final product structure and properties. In the present work, we aim at reviewing the latest developments in this field (i.e., the last five years by focusing on the chemistry of the systems at hand. As such, this should allow molecular designers to develop a toolbox for the synthesis of new systems with tailored properties for a given application.

  20. Chemistry of Covalent Organic Frameworks.

    Science.gov (United States)

    Waller, Peter J; Gándara, Felipe; Yaghi, Omar M

    2015-12-15

    Linking organic molecules by covalent bonds into extended solids typically generates amorphous, disordered materials. The ability to develop strategies for obtaining crystals of such solids is of interest because it opens the way for precise control of the geometry and functionality of the extended structure, and the stereochemical orientation of its constituents. Covalent organic frameworks (COFs) are a new class of porous covalent organic structures whose backbone is composed entirely of light elements (B, C, N, O, Si) that represent a successful demonstration of how crystalline materials of covalent solids can be achieved. COFs are made by combination of organic building units covalently linked into extended structures to make crystalline materials. The attainment of crystals is done by several techniques in which a balance is struck between the thermodynamic reversibility of the linking reactions and their kinetics. This success has led to the expansion of COF materials to include organic units linked by these strong covalent bonds: B-O, C-N, B-N, and B-O-Si. Since the organic constituents of COFs, when linked, do not undergo significant change in their overall geometry, it has been possible to predict the structures of the resulting COFs, and this advantage has facilitated their characterization using powder X-ray diffraction (PXRD) techniques. It has also allowed for the synthesis of COF structures by design and for their formation with the desired composition, pore size, and aperture. In practice, the modeled PXRD pattern for a given expected COF is compared with the experimental one, and depending on the quality of the match, this is used as a starting point for solving and then refining the crystal structure of the target COF. These characteristics make COFs an attractive class of new porous materials. Accordingly, they have been used as gas storage materials for energy applications, solid supports for catalysis, and optoelectronic devices. A large and

  1. Actor/Character Dualism

    DEFF Research Database (Denmark)

    Riis, Johannes

    2012-01-01

    Our perception of agency may be inherently fallible, and this may explain not only our general awareness of actors when engaged in fictional characters but also the specific case of paradoxical characters...

  2. Atomic Covalent Functionalization of Graphene

    Science.gov (United States)

    Johns, James E.; Hersam, Mark C.

    2012-01-01

    Conspectus Although graphene’s physical structure is a single atom thick, two-dimensional, hexagonal crystal of sp2 bonded carbon, this simple description belies the myriad interesting and complex physical properties attributed to this fascinating material. Because of its unusual electronic structure and superlative properties, graphene serves as a leading candidate for many next generation technologies including high frequency electronics, broadband photodetectors, biological and gas sensors, and transparent conductive coatings. Despite this promise, researchers could apply graphene more routinely in real-world technologies if they could chemically adjust graphene’s electronic properties. For example, the covalent modification of graphene to create a band gap comparable to silicon (~1 eV) would enable its use in digital electronics, and larger band gaps would provide new opportunities for graphene-based photonics. Towards this end, researchers have focused considerable effort on the chemical functionalization of graphene. Due to its high thermodynamic stability and chemical inertness, new methods and techniques are required to create covalent bonds without promoting undesirable side reactions or irreversible damage to the underlying carbon lattice. In this Account, we review and discuss recent theoretical and experimental work studying covalent modifications to graphene using gas phase atomic radicals. Atomic radicals have sufficient energy to overcome the kinetic and thermodynamic barriers associated with covalent reactions on the basal plane of graphene but lack the energy required to break the C-C sigma bonds that would destroy the carbon lattice. Furthermore, because they are atomic species, radicals substantially reduce the likelihood of unwanted side reactions that confound other covalent chemistries. Overall, these methods based on atomic radicals show promise for the homogeneous functionalization of graphene and the production of new classes of two

  3. Essays on Character & Opportunity

    Science.gov (United States)

    Center on Children and Families at Brookings, 2014

    2014-01-01

    These essays provide richer set of writings on the philosophical, empirical and practical issues raised by a focus on character, and in particular its relationship to questions of opportunity. Each one is an intellectual pemmican: sharp and to the point. Two scholars draw attention to the gendered nature of character formation (Segal and Lexmond);…

  4. Social character of materialism.

    Science.gov (United States)

    Chatterjee, A; Hunt, J M; Kernan, J B

    2000-06-01

    Scores for 170 undergraduates on Richins and Dawson's Materialism scale were correlated with scores on Kassarjian's Social Preference Scale, designed to measure individuals' character structure. A correlation of .26 between materialism and other-directed social character suggested that an externally oriented reference system guides materialists' perceptions, judgments, acquisitions, and possessions.

  5. Character Development in Adolescents.

    Science.gov (United States)

    Kessler, Glenn R.; And Others

    1986-01-01

    Explored the effects of a program consisting of communication and counseling skills, assertiveness training and moral dilemmas on the character development of high school students. The results demonstrated that the character development of the students in the experimental treatment group was affected significantly over time by the program.…

  6. Dynamic covalent gels assembled from small molecules:from discrete gelators to dynamic covalent polymers

    Institute of Scientific and Technical Information of China (English)

    Jian-Yong Zhang; Li-Hua Zeng; Juan Feng

    2017-01-01

    Dynamic covalent chemistry has emerged recently to be a powerful tool to construct functional materials.This article reviews the progress in the research and development of dynamic covalent chemistry in gels assembled from small molecules.First dynamic covalent reactions used in gels are reviewed to understand the dynamic covalent bonding.Afterwards the catalogues of dynamic covalent gels are reviewed according to the nature of gelators and the interactions between gelators.Dynamic covalent bonding can be involved to form low molecular weight gelators.Low molecular weight molecules with multiple functional groups react to form dynamic covalent cross-linked polymers and act as gelators.Two catalogues of gels show different properties arising from their different structures.This review aims to illustrate the structure-property relationships of these dynamic covalent gels.

  7. Madness in Shakespeare's Characters

    Directory of Open Access Journals (Sweden)

    Nuno Borja-Santos

    2014-10-01

    Full Text Available This paper begins with an introduction where the aims are explained: a psychopathological analysis of a Shakespearean character - Othello – followed by the discussion of the English dramatist’s importance in helping us understand madness in the emergent world of Renaissance. The main characteristics of Othello’s personality, which allowed the development of his jealousy delusion, are described. Finally, the conclusions underline the overlap of the symptoms developed by the character with the DSM-IV classification.

  8. Character, attitude and disposition

    OpenAIRE

    Webber, Jonathan

    2015-01-01

    Recent debate over the empirical psychological presuppositions of virtue ethics has focused on reactive behavioural dispositions. But there are many character traits that cannot be understood properly in this way. Such traits are well described by attitude psychology. Moreover, the findings of attitude psychology support virtue ethics in three ways. First, they confirm the role of habituation in the development of character. Further, they show virtue ethics to be compatible with the situation...

  9. Knowing Chinese character grammar.

    Science.gov (United States)

    Myers, James

    2016-02-01

    Chinese character structure has often been described as representing a kind of grammar, but the notion of character grammar has hardly been explored. Patterns in character element reduplication are particularly grammar-like, displaying discrete combinatoriality, binarity, phonology-like final prominence, and potentially the need for symbolic rules (X→XX). To test knowledge of these patterns, Chinese readers were asked to judge the acceptability of fake characters varying both in grammaticality (obeying or violating reduplication constraints) and in lexicality (of the reduplicative configurations). While lexical knowledge was important (lexicality improved acceptability and grammatical configurations were accepted more quickly when also lexical), grammatical knowledge was important as well, with grammaticality improving acceptability equally for lexical and nonlexical configurations. Acceptability was also higher for more frequent reduplicative elements, suggesting that the reduplicative configurations were decomposed. Chinese characters present an as-yet untapped resource for exploring fundamental questions about the nature of the human capacity for grammar. Copyright © 2015 Elsevier B.V. All rights reserved.

  10. Carbohydrate as covalent crosslink in human inter-alpha-trypsin inhibitor

    DEFF Research Database (Denmark)

    Jessen, T E; Faarvang, K L; Ploug, M

    1988-01-01

    The primary structure of inter-alpha-trypsin inhibitor is partially elucidated, but controversy about the construction of the polypeptide backbone still exists. We present evidence suggesting that inter-alpha-trypsin inhibitor represents a novel plasma protein structure with two separate polypept...... polypeptide chains covalently crosslinked only by carbohydrate (chondroitin sulphate)....

  11. Non-covalent and reversible functionalization of carbon nanotubes

    Directory of Open Access Journals (Sweden)

    Antonello Di Crescenzo

    2014-09-01

    Full Text Available Carbon nanotubes (CNTs have been proposed and actively explored as multipurpose innovative nanoscaffolds for applications in fields such as material science, drug delivery and diagnostic applications. Their versatile physicochemical features are nonetheless limited by their scarce solubilization in both aqueous and organic solvents. In order to overcome this drawback CNTs can be easily non-covalently functionalized with different dispersants. In the present review we focus on the peculiar hydrophobic character of pristine CNTs that prevent them to easily disperse in organic solvents. We report some interesting examples of CNTs dispersants with the aim to highlight the essential features a molecule should possess in order to act as a good carbon nanotube dispersant both in water and in organic solvents. The review pinpoints also a few examples of dispersant design. The last section is devoted to the exploitation of the major quality of non-covalent functionalization that is its reversibility and the possibility to obtain stimuli-responsive precipitation or dispersion of CNTs.

  12. The significant role of covalency in determining the ground state of cobalt phthalocyanines molecule

    Directory of Open Access Journals (Sweden)

    Jing Zhou

    2016-03-01

    Full Text Available To shed some light on the metal 3d ground state configuration of cobalt phthalocyanines system, so far in debate, we present an investigation by X-ray absorption spectroscopy (XAS at Co L2,3 edge and theoretical calculation. The density functional theory calculations reveal highly anisotropic covalent bond between central cobalt ion and nitrogen ligands, with the dominant σ donor accompanied by weak π-back acceptor interaction. Our combined experimental and theoretical study on the Co-L2,3 XAS spectra demonstrate a robust ground state of 2A1g symmetry that is built from 73% 3d7 character and 27% 3 d 8 L ¯ ( L ¯ denotes a ligand hole components, as the first excited-state with 2Eg symmetry lies about 158 meV higher in energy. The effect of anisotropic and isotropic covalency on the ground state was also calculated and the results indicate that the ground state with 2A1g symmetry is robust in a large range of anisotropic covalent strength while a transition of ground state from 2A1g to 2Eg configuration when isotropic covalent strength increases to a certain extent. Here, we address a significant anisotropic covalent effect of short Co(II-N bond on the ground state and suggest that it should be taken into account in determining the ground state of analogous cobalt complexes.

  13. Disorder phenomena in covalent semiconductors

    International Nuclear Information System (INIS)

    Popescu, M.A.

    1975-01-01

    The structure of the amorphous semiconductors has been investigated by means of X-ray diffraction and by computer simulation of random network models. Amorphous germanium contains mainly five and six-membered rings of atoms. In glassy state, the ternary compounds A 2 B 4 C 2 5 , such as CdGeAs 2 contain only even rings of atoms (six-membered and eight-membered rings). In the memory glasses of the type A 2 B 4 C 2 5 , such as GeAs 2 Te 7 , the valency state of every element is that from the crystal and important van der Waals forces are effective in the network. No Ge-Ge, Ge-As and As-As bonds are formed. The high pressure forms of the germanium have been simulated by computer. The force constants of the covalent bonds in Ge III and Ge IV differ from those in Ge I. The bond bending force constant decreases rapidly when the density of the crystal increases, a fact which has been imparted to a reduction of the sp 3 hybridization. The compressibility curve of the Ge I has been explained. The effect of the radial and uniaxial deformation on the non-crystalline networks has been studied. The compressibility of the amorphous germanium is by 1.5 per cent greater than that of crystalline germanium. The Poisson coefficient for a-Ge network is 0.233. The structure of the As 2 S 3 glass doped with different amounts of germanium (up to 40 at. per cent) and silver (up to 12 at. per cent) has been investigated. The As 2 S 3 Gesub(x) compositions are constituted from a disordered packing of structural units whose chemical composition and relative proportion in the glass essentially depends on the germanium content. (author)

  14. Covalent bonding in heavy metal oxides

    Energy Technology Data Exchange (ETDEWEB)

    Bagus, Paul S.; Nelin, Connie J.; Hrovat, Dave A.; Ilton, Eugene S.

    2017-04-07

    Novel theoretical methods were used to quantify the magnitude and the energetic contributions of 4f/5f-O2p and 5d/6d-O2p interactions to covalent bonding in lanthanide and actinide oxides. Although many analyses have neglected the involvement of the frontier d orbitals, the present study shows that f and d covalency are of comparable importance. Two trends are identified. As is expected, the covalent mixing is larger when the nominal oxidation state is higher. More subtly, the importance of the nf covalent mixing decreases sharply relative to (n+1)d as the nf occupation increases. Atomic properties of the metal cations that drive these trends are identified.

  15. Covalently linked bisporphyrins bearing tetraphenylporphyrin and ...

    Indian Academy of Sciences (India)

    Covalently linked bisporphyrins bearing tetraphenylporphyrin and perbromoporphyrin units: Synthesis and their properties. Puttaiah Bhyrappa V Krishnan ... yields of the TPP moiety. Electrochemical redox and fluorescence data seem to suggest the possible existence of intramolecular interactions in these bisporphyrins.

  16. Optical Character Recognition.

    Science.gov (United States)

    Converso, L.; Hocek, S.

    1990-01-01

    This paper describes computer-based optical character recognition (OCR) systems, focusing on their components (the computer, the scanner, the OCR, and the output device); how the systems work; and features to consider in selecting a system. A list of 26 questions to ask to evaluate systems for potential purchase is included. (JDD)

  17. About Chinese Characters

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    It is perhaps a facet of human nature that makes a person want to beking, and to control others. The character "王" was originally"王",symbolizing the emerald prayer beads worn exclusively by the king. Inthe course of this character’s evolution, however, new connotations were

  18. Covalent Surface Modifications of Carbon Nanotubes.

    Energy Technology Data Exchange (ETDEWEB)

    Pavia Sanders, Adriana [Sandia National Lab. (SNL-CA), Livermore, CA (United States); O' Bryan, Greg [Sandia National Lab. (SNL-CA), Livermore, CA (United States)

    2017-07-01

    A report meant to document the chemistries investigated by the author for covalent surface modification of CNTs. Oxidation, cycloaddition, and radical reactions were explored to determine their success at covalently altering the CNT surface. Characterization through infrared spectroscopy, Raman spectroscopy, and thermo gravimetric analysis was performed in order to determine the success of the chemistries employed. This report is not exhaustive and was performed for CNT surface modification exploration as it pertains to the "Next Gen" project.

  19. Cinematography and character depiction

    OpenAIRE

    William Francis Nicholson

    2011-01-01

    This essay investigates the ways in which cinematography can be used in depicting characters effectively in the motion picture medium. Since an aspiring filmmaker may be overwhelmed by the expansive field of cinematography, this essay aims to demystify and systematise this aspect of filmmaking. It combines information from written sources (mostly text books on filmmaking and cinematography) with observations made from viewing recent and older feature films. The knowledge is organised under th...

  20. CovalentDock Cloud: a web server for automated covalent docking.

    Science.gov (United States)

    Ouyang, Xuchang; Zhou, Shuo; Ge, Zemei; Li, Runtao; Kwoh, Chee Keong

    2013-07-01

    Covalent binding is an important mechanism for many drugs to gain its function. We developed a computational algorithm to model this chemical event and extended it to a web server, the CovalentDock Cloud, to make it accessible directly online without any local installation and configuration. It provides a simple yet user-friendly web interface to perform covalent docking experiments and analysis online. The web server accepts the structures of both the ligand and the receptor uploaded by the user or retrieved from online databases with valid access id. It identifies the potential covalent binding patterns, carries out the covalent docking experiments and provides visualization of the result for user analysis. This web server is free and open to all users at http://docking.sce.ntu.edu.sg/.

  1. A REVIEW: OPTICAL CHARACTER RECOGNITION

    OpenAIRE

    Swati Tomar*1 & Amit Kishore2

    2018-01-01

    This paper presents detailed review in the field of Optical Character Recognition. Various techniques are determine that have been proposed to realize the center of character recognition in an optical character recognition system. Even though, sufficient studies and papers are describes the techniques for converting textual content from a paper document into machine readable form. Optical character recognition is a process where the computer understands automatically the image of handwritten ...

  2. Actualism and Fictional Characters

    Directory of Open Access Journals (Sweden)

    André Leclerc

    2016-04-01

    Full Text Available http://dx.doi.org/10.5007/1808-1711.2016v20n1p61 In what follows, I present only part of a program that consists in developing a version of actualism as an adequate framework for the metaphysics of intentionality. I will try to accommodate in that framework suggestions found in Kripke’s works and some positions developed by Amie Thomasson. What should we change if we accept “fictional entities” in the domain of the actual world? Actualism is the thesis that everything that exists belongs to the domain of the actual world and that there are no possibilia. I shall defend that there are abstract artefacts, like fictional characters, and institutions. My argument could be seen as a version of Moore’s paradox: it is paradoxical to say: “I made (created it, but I do not believe it exists”. Moreover, there are true sentences about them. I will examine what it means to include abstract artefacts in the domain of the actual world. I favour a use of “exist” that includes beings with no concrete occupation of tri-dimensional space; to exist, it is enough to have been introduced at some moment in history. Abstract artefacts, like fictional characters, exist in that sense. I argue that it is important to distinguish two perspectives (internal and external in order to clarify the kind of knowledge we have of fictional characters. However, their existence presupposes a relation of dependence to a material basis and the mental activities of many people.

  3. The typeface character

    DEFF Research Database (Denmark)

    Beier, Sofie

    2015-01-01

    Research from the fields of neuroscience and psychology, shows that typefaces can carry different semantic associations. However, to be able to read a text, the reader can no longer focus on the character of the typeface, as the human mind is incapable of simultaneously giving full attention to d...... to different matters. This results in the inherent conflict of typefaces that they on one hand need to draw attention to themselves, and on the other hand need to let go of this attention for the content to be read....

  4. Assessing Covalency in Cerium and Uranium Hexachlorides: A Correlated Wavefunction and Density Functional Theory Study

    Directory of Open Access Journals (Sweden)

    Reece Beekmeyer

    2015-11-01

    Full Text Available The electronic structure of a series of uranium and cerium hexachlorides in a variety of oxidation states was evaluated at both the correlated wavefunction and density functional (DFT levels of theory. Following recent experimental observations of covalency in tetravalent cerium hexachlorides, bonding character was studied using topological and integrated analysis based on the quantum theory of atoms in molecules (QTAIM. This analysis revealed that M–Cl covalency was strongly dependent on oxidation state, with greater covalency found in higher oxidation state complexes. Comparison of M–Cl delocalisation indices revealed a discrepancy between correlated wavefunction and DFT-derived values. Decomposition of these delocalisation indices demonstrated that the origin of this discrepancy lay in ungerade contributions associated with the f-manifold which we suggest is due to self-interaction error inherent to DFT-based methods. By all measures used in this study, extremely similar levels of covalency between complexes of U and Ce in the same oxidation state was found.

  5. Abusive families and character formation.

    Science.gov (United States)

    McCarthy, J B

    1990-06-01

    Family research studies confirm that abusive parents tend to be undifferentiated partners who compete with each other and with their children for attention and nurturance. More or less healthy parents make demands on children to counteract their own injured narcissism, but they do so largely without devaluation and the sadistic use of projective identification. Under sufficient stress abusive parents attack the child who fails to gratify their needs, thereby giving vent to longstanding frustrations and feelings of being threatened by the child's individuation and competency. The emotional atmosphere in such families facilitates ego deficits like those of the borderline personality as it molds the child's efforts to avoid anxiety. Devaluation, loss, and defenses against mourning partially account for depression and paranoid traits in abused youngsters. Early neglect and abuse exposes them to influential models who act out rage and primitive defenses. Some abused individuals project their rage and later become paranoid or antisocial, whereas others fragment or retain infantile defenses. The destructiveness of severe psychological abuse lies in the constriction of the experiencing self and healthy character development, together with the conditioning to repeat abusive relationships and to avoid intimacy. Achieving individuation under these circumstances entails overcoming the internalized abusive relationships and relinquishing the unconscious wish to be transformed from the abused into the abuser.

  6. Covalent biofunctionalization of silicon nitride surfaces

    NARCIS (Netherlands)

    Arafat, A.; Giesbers, M.; Rosso, M.; Sudhölter, E.J.R.; Schroën, C.G.P.H.; White, R.G.; Li Yang,; Linford, M.R.; Zuilhof, H.

    2007-01-01

    Covalently attached organic monolayers on etched silicon nitride (SixN4; x 3) surfaces were prepared by reaction of SixN4-coated wafers with neat or solutions of 1-alkenes and 1-alkynes in refluxing mesitylene. The surface modification was monitored by measurement of the static water contact angle,

  7. Covalent functionalization of graphene with reactive intermediates.

    Science.gov (United States)

    Park, Jaehyeung; Yan, Mingdi

    2013-01-15

    Graphene, a material made exclusively of sp(2) carbon atoms with its π electrons delocalized over the entire 2D network, is somewhat chemically inert. Covalent functionalization can enhance graphene's properties including opening its band gap, tuning conductivity, and improving solubility and stability. Covalent functionalization of pristine graphene typically requires reactive species that can form covalent adducts with the sp(2) carbon structures in graphene. In this Account, we describe graphene functionalization reactions using reactive intermediates of radicals, nitrenes, carbenes, and arynes. These reactive species covalently modify graphene through free radical addition, CH insertion, or cycloaddition reactions. Free radical additions are among the most common reaction, and these radicals can be generated from diazonium salts and benzoyl peroxide. Electron transfer from graphene to aryl diazonium ion or photoactivation of benzoyl peroxide yields aryl radicals that subsequently add to graphene to form covalent adducts. Nitrenes, electron-deficient species generated by thermal or photochemical activation of organic azides, can functionalize graphene very efficiently. Because perfluorophenyl nitrenes show enhanced bimolecular reactions compared with alkyl or phenyl nitrenes, perfluorophenyl azides are especially effective. Carbenes are used less frequently than nitrenes, but they undergo CH insertion and C═C cycloaddition reactions with graphene. In addition, arynes can serve as a dienophile in a Diels-Alder type reaction with graphene. Further study is needed to understand and exploit the chemistry of graphene. The generation of highly reactive intermediates in these reactions leads to side products that complicate the product composition and analysis. Fundamental questions remain about the reactivity and regioselectivity of graphene. The differences in the basal plane and the undercoordinated edges of graphene and the zigzag versus arm-chair configurations

  8. A method for synthesis and functionalization of ultrasmall superparamagnetic covalent carriers based on maghemite and dextran

    International Nuclear Information System (INIS)

    Mornet, Stephane; Portier, Josik; Duguet, Etienne

    2005-01-01

    A new generation of susceptibility contrast agents for MRI and based on maghemite cores covalently bonded to dextran stabilizing macromolecules was investigated. The multistep preparation of these versatile ultrasmall superparamagnetic iron oxides (VUSPIO) consisted of colloidal maghemite synthesis, surface modification by aminopropylsilane groups, and coupling of partially oxidized dextran via Schiff's bases and secondary amine bonds. The dextran corona might be easily derivatized, e.g. by PEGylation

  9. Maya Studio Projects Photorealistic Characters

    CERN Document Server

    Palamar, Todd

    2011-01-01

    Create realistic characters with Maya tools and this project-based book Maya character generation tools are extremely sophisticated, and there's no better way to learn all their capabilities than by working through the projects in this hands-on book. This official guide focuses on understanding and implementing Maya's powerful tools for creating realistic characters for film, games, and TV. Use a variety of tools to create characters from skeleton to clothing, including hairstyles and facial hair, and learn how to use Performance Capture. A DVD includes supplementary videos, project support fi

  10. Which "Character" Should Sport Develop?

    Science.gov (United States)

    Rudd, Andy

    2005-01-01

    For years, strong claims have been made that sport builds character. Despite such claims, a "winning at all cost" mentality can frequently be seen within all of sport. The reason for this paradox may relate to confusion around what it means to demonstrate character. The purpose of this article is to show that there are indeed two distinct types of…

  11. THE NEED FOR CHARACTER EDUCATION

    Directory of Open Access Journals (Sweden)

    Aynur Pala

    2011-07-01

    Full Text Available Character education is a national movement creatingschools that foster ethical,responsible and caring young people by modelling and teaching good characterthrough emphasis on universal values that we all share. It is the intentional,proactive effort by schools, districts and states to instil in their students importantcore ethical values such as caring, honesty, fairness, responsibility and respect forself and others.Good character is not formed automatically; it is developed over time through asustained process of teaching, example, learning and practice. It is developedthrough character education. The intentional teaching of good character isparticularly important in today’s society since ouryouth face many opportunitiesand dangers unknown to earlier generations. They are bombarded with many morenegative influences through the media and other external sources prevalent intoday’s culture. Since children spend about 900 hours a year in school, it isessential that schools resume a proactive role in assisting families andcommunities by developing caring, respectful environments where students learncore, ethical values. When a comprehensive approachto character education isused, a positive moral culture is created in the school—a total school environmentthat supports the values taught in the classroom (Character Education Partnership,2010.The aim of this study is to provide guidelines forthe elements need for effectiveand comprehensive character education. And to emphasize the need of charactereducation to help students develop good character, which includes knowing,caring about and acting upon core ethical values such as respect, responsibility,honesty, fairness and compassion.

  12. Holistic Processing of Chinese Characters

    Directory of Open Access Journals (Sweden)

    Alan Chun-Nang Wong

    2011-05-01

    Full Text Available Enhanced holistic processing (obligatory attention to all parts of an object has been associated with different types of perceptual expertise involving faces, cars, fingerprints, musical notes, English words, etc. Curiously Chinese characters are regarded as an exception, as indicated by the lack of holistic processing found for experts (Hsiao and Cottrell, 2009. The ceiling performance of experts, however, may have caused this null effect. We revisit this issue by adopting the often-used face-composite sequential-matching task to two-part Chinese characters. Participants matched the target halves (left or right of two characters while ignoring the irrelevant halves. Both Chinese readers (experts and non-Chinese readers (novices showed holistic processing. Follow-up experiments suggested different origins of the effects for the two groups. For experts, holistic processing was sensitive to the amount of experience with the characters, as it was larger for words than non-words (formed by swapping the two parts of a valid character. Novices, however, showed similar degree of holistic processing to words and non-words, suggesting that their effects were more related to their inefficient decomposition of a complex, character-like pattern into parts. Overall these findings suggest that holistic processing may be a marker of expertise with Chinese characters, contrary to previous claims.

  13. Covalent modification of platelet proteins by palmitate

    International Nuclear Information System (INIS)

    Muszbek, L.; Laposata, M.

    1989-01-01

    Covalent attachment of fatty acid to proteins plays an important role in association of certain proteins with hydrophobic membrane structures. In platelets, the structure of many membrane glycoproteins (GPs) has been examined in detail, but the question of fatty acid acylation of platelet proteins has not been addressed. In this study, we wished to determine (a) whether platelet proteins could be fatty acid acylated; and, if so, (b) whether these modified proteins were present in isolated platelet membranes and cytoskeletal fractions; and (c) if the pattern of fatty acid acylated proteins changed on stimulation of the platelets with the agonist thrombin. We observed that in platelets allowed to incorporate 3H-palmitate, a small percentage (1.37%) of radioactivity incorporated into the cells became covalently bound to protein. Selective cleavage of thioester, thioester plus O-ester, and amide-linked 3H-fatty acids from proteins, and their subsequent analysis by high-performance liquid chromatography (HPLC) indicated that the greatest part of 3H-fatty acid covalently bound to protein was thioester-linked 3H-palmitate. By sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and fluorography, at least ten major radiolabeled proteins were detected. Activation of platelets by thrombin greatly increased the quantity of 3H-palmitoylated proteins associated with the cytoskeleton. Nearly all radiolabeled proteins were recovered in the membrane fraction, indicating that these proteins are either integral or peripheral membrane proteins or proteins tightly associated to membrane constituents. Components of the GPIIb-IIIa complex were not palmitoylated. Thus, platelet proteins are significantly modified posttranslationally by 3H-palmitate, and incorporation of palmitoylated proteins into the cytoskeleton is a prominent component of the platelet response to thrombin stimulation

  14. Design of a covalently bonded glycosphingolipid microarray

    DEFF Research Database (Denmark)

    Arigi, Emma; Blixt, Klas Ola; Buschard, Karsten

    2012-01-01

    , the major classes of plant and fungal GSLs. In this work, a prototype "universal" GSL-based covalent microarray has been designed, and preliminary evaluation of its potential utility in assaying protein-GSL binding interactions investigated. An essential step in development involved the enzymatic release...... of the fatty acyl moiety of the ceramide aglycone of selected mammalian GSLs with sphingolipid N-deacylase (SCDase). Derivatization of the free amino group of a typical lyso-GSL, lyso-G(M1), with a prototype linker assembled from succinimidyl-[(N-maleimidopropionamido)-diethyleneglycol] ester and 2...

  15. Character profiles and life satisfaction.

    Science.gov (United States)

    Park, Hwanjin; Suh, Byung Seong; Kim, Won Sool; Lee, Hye-Kyung; Park, Seon-Cheol; Lee, Kounseok

    2015-04-01

    There is a surge of interest in subjective well-being (SWB), which concerns how individuals feel about their happiness. Life satisfaction tends to be influenced by individual psychological traits and external social factors. The aim of this study was to examine the relationship between individual character and SWB. Data from 3522 university students were analyzed in this study. Character profiles were evaluated using the Temperament and Character Inventory-Revised Short version (TCI-RS). Life satisfaction was assessed using the Satisfaction with Life Scale (SWLS). All statistical tests regarding the correlations between each character profile and life satisfaction were conducted using ANOVAs, t-tests, multiple linear regression models and correlation analyses. The creative (SCT) profile was associated with the highest levels of life satisfaction, whereas the depressive (sct) profile was associated with the lowest levels of life satisfaction. Additionally, high self-directedness, self-transcendence and cooperation were associated with high life satisfaction. The results of gender-adjusted multiple regression analysis showed that the effects of self-directedness were the strongest in the assessment of one's quality of life, followed by self-transcendence and cooperativeness, in that order. All of the three-character profiles were significantly correlated with one's quality of life, and the character profiles of TCI-RS explained 27.6% of life satisfaction in total. Among the three-character profiles, the self-directedness profile was most associated with life satisfaction. Our study was cross-sectional, and self-reported data from students at a single university were analyzed. The results of this study showed that, among the character profiles, the effects of self-directedness were the strongest for predicting life satisfaction. Copyright © 2014 Elsevier Inc. All rights reserved.

  16. Moral character in the workplace.

    Science.gov (United States)

    Cohen, Taya R; Panter, A T; Turan, Nazli; Morse, Lily; Kim, Yeonjeong

    2014-11-01

    Using two 3-month diary studies and a large cross-sectional survey, we identified distinguishing features of adults with low versus high levels of moral character. Adults with high levels of moral character tend to: consider the needs and interests of others and how their actions affect other people (e.g., they have high levels of Honesty-Humility, empathic concern, guilt proneness); regulate their behavior effectively, specifically with reference to behaviors that have positive short-term consequences but negative long-term consequences (e.g., they have high levels of Conscientiousness, self-control, consideration of future consequences); and value being moral (e.g., they have high levels of moral identity-internalization). Cognitive moral development, Emotionality, and social value orientation were found to be relatively undiagnostic of moral character. Studies 1 and 2 revealed that employees with low moral character committed harmful work behaviors more frequently and helpful work behaviors less frequently than did employees with high moral character, according to their own admissions and coworkers' observations. Study 3 revealed that adults with low moral character committed more delinquent behavior and had more lenient attitudes toward unethical negotiation tactics than did adults with high moral character. By showing that individual differences have consistent, meaningful effects on employees' behaviors, after controlling for demographic variables (e.g., gender, age, income) and basic attributes of the work setting (e.g., enforcement of an ethics code), our results contest situationist perspectives that deemphasize the importance of personality. Moral people can be identified by self-reports in surveys, and these self-reports predict consequential behaviors months after the initial assessment.

  17. Revisiting nitrogen species in covalent triazine frameworks

    KAUST Repository

    Osadchii, Dmitrii Yu.

    2017-11-28

    Covalent triazine frameworks (CTFs) are porous organic materials promising for applications in catalysis and separation due to their high stability, adjustable porosity and intrinsic nitrogen functionalities. CTFs are prepared by ionothermal trimerization of aromatic nitriles, however, multiple side reactions also occur under synthesis conditions, and their influence on the material properties is still poorly described. Here we report the systematic characterization of nitrogen in CTFs using X-ray photoelectron spectroscopy (XPS). With the use of model compounds, we could distinguish several types of nitrogen species. By combining these data with textural properties, we unravel the influence that the reaction temperature, the catalyst and the monomer structure and composition have on the properties of the resulting CTF materials.

  18. Non-covalent associative structure of coal

    Energy Technology Data Exchange (ETDEWEB)

    Shui, H. [Anhui University of Technology, Maanshan (China). School of Chemistry and Chemical Engineering

    2004-06-01

    The recent progress of non-covalent associative structure of coal and the mechanisms of the carbon disulphide-N-methyl-2-pyrrolidone (CS{sub 2}/NMP) are mixed solvent and the additive addition enhancing the extraction yield of coals are reviewed, and the aggregation behaviour of coal in solid and solution states are presented, and the aggregation behavior of coal in solid and solution states are introduced in this paper. Coal extraction and swelling in organic solvents at room temperature were the most useful methods to understand the associative structure of coal. CS{sub 2}/NMP is a unique solvent to give high extraction yields for some bituminous coals. Some additives such as tetracyanoethylene (TCNE) can dissociate the stronger interactions among coal molecules and enhance the extraction yields of coal in the mixed solvent. 37 refs., 1 fig.

  19. Novel hydroxyapatite biomaterial covalently linked to raloxifene.

    Science.gov (United States)

    Meme, L; Santarelli, A; Marzo, G; Emanuelli, M; Nocini, P F; Bertossi, D; Putignano, A; Dioguardi, M; Lo Muzio, L; Bambini, F

    2014-01-01

    Since raloxifene, a drug used in osteoporosis therapy, inhibits osteoclast, but not osteoblast functions, it has been suggested to improve recovery during implant surgery. The present paper describes an effective method to link raloxifene, through a covalent bond, to a nano-Hydroxyapatite-based biomaterial by interfacing with (3-aminopropyl)-Triethoxysilane as assessed by Infra Red-Fourier Transformed (IR-FT) spectroscopy and Scanning Electron Microscope (SEM). To evaluate the safety of this modified new material, the vitality of osteoblast-like cells cultured with the new biomaterial was then investigated. Raloxifene-conjugated HAbiomaterial has been shown to be a safe material easy to obtain which could be an interesting starting point for the use of a new functional biomaterial suitable in bone regeneration procedures.

  20. Biofunctional Paper via Covalent Modification of Cellulose

    Science.gov (United States)

    Yu, Arthur; Shang, Jing; Cheng, Fang; Paik, Bradford A.; Kaplan, Justin M.; Andrade, Rodrigo B.; Ratner, Daniel M.

    2012-01-01

    Paper-based analytical devices are the subject of growing interest for the development of low-cost point-of-care diagnostics, environmental monitoring technologies and research tools for limited-resource settings. However, there are limited chemistries available for the conjugation of biomolecules to cellulose for use in biomedical applications. Herein, divinyl sulfone (DVS) chemistry was demonstrated to covalently immobilize small molecules, proteins and DNA onto the hydroxyl groups of cellulose membranes through nucleophilic addition. Assays on modified cellulose using protein-carbohydrate and protein-glycoprotein interactions as well as oligonucleotide hybridization showed that the membrane’s bioactivity was specific, dose-dependent, and stable over a long period of time. Use of an inkjet printer to form patterns of biomolecules on DVS-activated cellulose illustrates the adaptability of the DVS functionalization technique to pattern sophisticated designs, with potential applications in cellulose-based lateral flow devices. PMID:22708701

  1. Revisiting nitrogen species in covalent triazine frameworks

    KAUST Repository

    Osadchii, Dmitrii Yu.; Olivos Suarez, Alma Itzel; Bavykina, Anastasiya V.; Gascon, Jorge

    2017-01-01

    Covalent triazine frameworks (CTFs) are porous organic materials promising for applications in catalysis and separation due to their high stability, adjustable porosity and intrinsic nitrogen functionalities. CTFs are prepared by ionothermal trimerization of aromatic nitriles, however, multiple side reactions also occur under synthesis conditions, and their influence on the material properties is still poorly described. Here we report the systematic characterization of nitrogen in CTFs using X-ray photoelectron spectroscopy (XPS). With the use of model compounds, we could distinguish several types of nitrogen species. By combining these data with textural properties, we unravel the influence that the reaction temperature, the catalyst and the monomer structure and composition have on the properties of the resulting CTF materials.

  2. Pore surface engineering in covalent organic frameworks.

    Science.gov (United States)

    Nagai, Atsushi; Guo, Zhaoqi; Feng, Xiao; Jin, Shangbin; Chen, Xiong; Ding, Xuesong; Jiang, Donglin

    2011-11-15

    Covalent organic frameworks (COFs) are a class of important porous materials that allow atomically precise integration of building blocks to achieve pre-designable pore size and geometry; however, pore surface engineering in COFs remains challenging. Here we introduce pore surface engineering to COF chemistry, which allows the controlled functionalization of COF pore walls with organic groups. This functionalization is made possible by the use of azide-appended building blocks for the synthesis of COFs with walls to which a designable content of azide units is anchored. The azide units can then undergo a quantitative click reaction with alkynes to produce pore surfaces with desired groups and preferred densities. The diversity of click reactions performed shows that the protocol is compatible with the development of various specific surfaces in COFs. Therefore, this methodology constitutes a step in the pore surface engineering of COFs to realize pre-designed compositions, components and functions.

  3. Cell Signalling Through Covalent Modification and Allostery

    Science.gov (United States)

    Johnson, Louise N.

    Phosphorylation plays essential roles in nearly every aspect of cell life. Protein kinases catalyze the transfer of the γ-phosphate of ATP to a serine, threonine or tyrosine residue in protein substrates. This covalent modification allows activation or inhibition of enzyme activity, creates recognition sites for other proteins and promotes order/disorder or disorder/order transitions. These properties regulate ­signalling pathways and cellular processes that mediate metabolism, transcription, cell cycle progression, differentiation, cytoskeleton arrangement and cell movement, apoptosis, intercellular communication, and neuronal and immunological functions. In this lecture I shall review the structural consequences of protein phosphorylation using our work on glycogen phosphorylase and the cell cycle cyclin dependent protein kinases as illustrations. Regulation of protein phosphorylation may be disrupted in the diseased state and protein kinases have become high profile targets for drug development. To date there are 11 compounds that have been approved for clinical use in the treatment of cancer.

  4. Factorized combinations of Virasoro characters

    International Nuclear Information System (INIS)

    Bytsko, A.G.; Fring, A.

    2000-01-01

    We investigate linear combinations of characters for minimal Virasoro models which are representable as a product of several basic blocks. Our analysis is based on consideration of asymptotic behaviour of the characters in the quasi-classical limit. In particular, we introduce a notion of the secondary effective central charge. We find all possible cases for which factorization occurs on the base of the Gauss-Jacobi or the Watson identities. Exploiting these results, we establish various types of identities between different characters. In particular, we present several identities generalizing the Rogers-Ramanujan identities. Applications to quasi-particle representations, modular invariant partition functions, super-conformal theories and conformal models with boundaries are briefly discussed. (orig.)

  5. Introducing Character Animation with Blender

    CERN Document Server

    Mullen, Tony

    2011-01-01

    Introducing Character Animation with Blender, 2nd Edition is written in a friendly but professional tone, with clear descriptions and numerous illustrative screenshots. Throughout the book, tutorials focus on how to accomplish actual animation goals, while illustrating the necessary technical methods along the way. These are reinforced by clear descriptions of how each specific aspect of Blender works and fits together with the rest of the package. By following all the tutorials, the reader will gain all the skills necessary to build and animate a well-modeled, fully-rigged character of their

  6. Covalent versus ionic bonding in alkalimetal fluoride oligomers

    NARCIS (Netherlands)

    Bickelhaupt, F.M.; Sola, M.; Fonseca Guerra, C.

    2007-01-01

    The most polar bond in chemistry is that between a fluorine and an alkalimetal atom. Inspired by our recent finding that other polar bonds (C - M and H - M) have important covalent contributions (i.e., stabilization due to bond overlap), we herein address the question if covalency is also essential

  7. Covalent Modification of Highly Ordered Pyrolytic Graphite with a Stable Organic Free Radical by Using Diazonium Chemistry.

    Science.gov (United States)

    Seber, Gonca; Rudnev, Alexander V; Droghetti, Andrea; Rungger, Ivan; Veciana, Jaume; Mas-Torrent, Marta; Rovira, Concepció; Crivillers, Núria

    2017-01-26

    A novel, persistent, electrochemically active perchlorinated triphenylmethyl (PTM) radical with a diazonium functionality has been covalently attached to highly ordered pyrolytic graphite (HOPG) by electrografting in a single-step process. Electrochemical scanning tunneling microscopy (EC-STM) and Raman spectroscopy measurements revealed that PTM molecules had a higher tendency to covalently react at the HOPG step edges. The cross-section profiles from EC-STM images showed that there was current enhancement at the functionalized areas, which could be explained by redox-mediated electron tunneling through surface-confined redox-active molecules. Cyclic voltammetry clearly demonstrated that the intrinsic properties of the organic radical were preserved upon grafting and DFT calculations also revealed that the magnetic character of the PTM radical was preserved. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. Partial Cancellation

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. Partial Cancellation. Full Cancellation is desirable. But complexity requirements are enormous. 4000 tones, 100 Users billions of flops !!! Main Idea: Challenge: To determine which cross-talker to cancel on what “tone” for a given victim. Constraint: Total complexity is ...

  9. A Study of Character among Collegiate Athletes

    Science.gov (United States)

    Heupel, Jill D.

    2017-01-01

    The idea that sport builds character has been around for a long time. However, sports may not build the type of character once thought. Character of athletes was defined based on differing views held by sport scholars, coaches, athletes, and sport enthusiast. Sport scholars tend to view character of athletes from a moral perspective. Coaches,…

  10. Building Character through Literacy with Children's Literature

    Science.gov (United States)

    Almerico, Gina M.

    2014-01-01

    Character education is described as curriculum specifically developed to teach children about the quality and traits of good character. One means in which children can learn about good character is through the pages of high quality children's literature. In this study, the author defines the characteristics of an effective character development…

  11. Identification Of Minangkabau Landscape Characters

    Science.gov (United States)

    Asrina, M.; Gunawan, A.; Aris, Munandar

    2017-10-01

    Minangkabau is one of cultures in indonesia which occupies landscape intact. Landscape of Minangkabau have a very close relationship with the culture of the people. Uniqueness of Minangkabau culture and landscape forming an inseparable characterunity. The landscape is necessarily identified to know the inherent landscape characters. The objective of this study was to identify the character of the Minangkabau landscape characterizes its uniqueness. The study was conducted by using descriptive method comprised literature review and field observasion. Observed the landscape characters comprised two main features, they were major and minor features. Indetification of the features was conducted in two original areas (darek) of the Minangkabau traditional society. The research results showed that major features or natural features of the landscape were predominantly landform, landcover, and hidrology. All luhak (districts) of Minangkabau showed similar main features such as hill, canyon, lake, valley, and forest. The existence of natural features such as hills, canyon and valleys characterizes the nature of minangkabau landscape. Minor features formed by Minangkabau cultural society were agricultural land and settlement. Rumah gadang (big house) is one of famous minor features characterizes the Minangkabau culture. In addition, several historical artefacts of building and others structure may strengthen uniqueness of the Minangkabau landscape character, such as The royal palace, inscription, and tunnels.

  12. Recognition of isolated handprinted characters

    DEFF Research Database (Denmark)

    Martins, Bo

    1996-01-01

    Handprinted characters are of unequal complexity and a common description of all alphabet symbols seems therefore unobtainable. However, letters which confuse human beings and man-made OCR systems usually have approximately the same appearance and may therefore be modeled jointly. We part the set...

  13. Understanding Agency and Educating Character

    Science.gov (United States)

    Roth, Klas

    2011-01-01

    How can we understand human agency, and what does it mean to educate character? In this essay Klas Roth develops a Kantian notion, one that suggests we render ourselves efficacious and autonomous in education and elsewhere. This requires, among other things, that we are successful in bringing about the intended result through our actions and the…

  14. Character Toys as Psychological Tools

    Science.gov (United States)

    Smirnova, Elena O.

    2011-01-01

    The main characteristic of children's play is its mental aspect--the fact that it is based on thoughts and feelings and not on objective reality. During imaginary play, children go beyond the limits of reality, and toys are tools that help them to do this. Children need character toys--toys that play the role of companion or partner--in the early…

  15. Can Youth Sport Build Character?

    Science.gov (United States)

    Shields, David Light; Bredemeier, Brenda Light; Power, F. Clark

    2001-01-01

    Participation and competition in some sports are associated with lower stages of moral reasoning. Coaches can foster moral development by starting with the right mental model, holding benchmark meetings about team values, setting goals for physical and character skills, making time for guided discussion sessions, building community, modeling…

  16. Braille Character Recognition Using Artificial Neural Network

    OpenAIRE

    Subur, Joko; Sardjono, Tri Arief; Mardiyanto, Ronny

    2015-01-01

    Braille letter is characters designed for the blind, consist of six embossed points, arranged in a standard braille character. Braille letters is touched and read using fingers, therefore the sensitivity of the fingers is important. Those characters need to be memorized, so it is very difficult to be learned. The aim of this research is to create a braille characters recognition system and translate it to alpha-numeric text. Webcam camera is used to capture braille image from braille characte...

  17. Partial processing

    International Nuclear Information System (INIS)

    1978-11-01

    This discussion paper considers the possibility of applying to the recycle of plutonium in thermal reactors a particular method of partial processing based on the PUREX process but named CIVEX to emphasise the differences. The CIVEX process is based primarily on the retention of short-lived fission products. The paper suggests: (1) the recycle of fission products with uranium and plutonium in thermal reactor fuel would be technically feasible; (2) it would, however, take ten years or more to develop the CIVEX process to the point where it could be launched on a commercial scale; (3) since the majority of spent fuel to be reprocessed this century will have been in storage for ten years or more, the recycling of short-lived fission products with the U-Pu would not provide an effective means of making refabrication fuel ''inaccessible'' because the radioactivity associated with the fission products would have decayed. There would therefore be no advantage in partial processing

  18. Partial gigantism

    Directory of Open Access Journals (Sweden)

    М.М. Karimova

    2017-05-01

    Full Text Available A girl with partial gigantism (the increased I and II fingers of the left foot is being examined. This condition is a rare and unresolved problem, as the definite reason of its development is not determined. Wait-and-see strategy is recommended, as well as correcting operations after closing of growth zones, and forming of data pool for generalization and development of schemes of drug and radial therapeutic methods.

  19. Detection of HBV Covalently Closed Circular DNA

    Directory of Open Access Journals (Sweden)

    Xiaoling Li

    2017-06-01

    Full Text Available Chronic hepatitis B virus (HBV infection affects approximately 240 million people worldwide and remains a serious public health concern because its complete cure is impossible with current treatments. Covalently closed circular DNA (cccDNA in the nucleus of infected cells cannot be eliminated by present therapeutics and may result in persistence and relapse. Drug development targeting cccDNA formation and maintenance is hindered by the lack of efficient cccDNA models and reliable cccDNA detection methods. Southern blotting is regarded as the gold standard for quantitative cccDNA detection, but it is complicated and not suitable for high-throughput drug screening, so more sensitive and simple methods, including polymerase chain reaction (PCR-based methods, Invader assays, in situ hybridization and surrogates, have been developed for cccDNA detection. However, most methods are not reliable enough, and there are no unified standards for these approaches. This review will summarize available methods for cccDNA detection. It is hoped that more robust methods for cccDNA monitoring will be developed and that standard operation procedures for routine cccDNA detection in scientific research and clinical monitoring will be established.

  20. Protein covalent modification by biologically active quinones

    Directory of Open Access Journals (Sweden)

    MIROSLAV J. GASIC

    2004-11-01

    Full Text Available The avarone/avarol quinone/hydroquinone couple shows considerable antitumor activity. In this work, covalent modification of b-lactoglobulin by avarone and its derivatives as well as by the synthetic steroidal quinone 2,5(10-estradiene-1,4,17-trione and its derivatives were studied. The techniques for studying chemical modification of b-lactoglobulin by quinones were: UV/Vis spectrophotometry, SDS PAGE and isoelectrofocusing. SDS PAGE results suggest that polymerization of the protein occurs. It could be seen that the protein of 18 kD gives the bands of 20 kD, 36 kD, 40 kD, 45 kD, 64 kD and 128 kD depending on modification agent. The shift of the pI of the protein (5.4 upon modification toward lower values (from pI 5.0 to 5.3 indicated that lysine amino groups are the principal site of the reaction of b-lactoglobulin with the quinones.

  1. Covalently crosslinked diels-alder polymer networks.

    Energy Technology Data Exchange (ETDEWEB)

    Bowman, Christopher (University of Colorado, Boulder, CO); Adzima, Brian J. (University of Colorado, Boulder, CO); Anderson, Benjamin John

    2011-09-01

    This project examines the utility of cycloaddition reactions for the synthesis of polymer networks. Cycloaddition reactions are desirable because they produce no unwanted side reactions or small molecules, allowing for the formation of high molecular weight species and glassy crosslinked networks. Both the Diels-Alder reaction and the copper-catalyzed azide-alkyne cycloaddition (CuAAC) were studied. Accomplishments include externally triggered healing of a thermoreversible covalent network via self-limited hysteresis heating, the creation of Diels-Alder based photoresists, and the successful photochemical catalysis of CuAAC as an alternative to the use of ascorbic acid for the generation of Cu(I) in click reactions. An analysis of the results reveals that these new methods offer the promise of efficiently creating robust, high molecular weight species and delicate three dimensional structures that incorporate chemical functionality in the patterned material. This work was performed under a Strategic Partnerships LDRD during FY10 and FY11 as part of a Sandia National Laboratories/University of Colorado-Boulder Excellence in Science and Engineering Fellowship awarded to Brian J. Adzima, a graduate student at UC-Boulder. Benjamin J. Anderson (Org. 1833) was the Sandia National Laboratories point-of-contact for this fellowship.

  2. On characters of finite groups

    CERN Document Server

    Broué, Michel

    2017-01-01

    This book explores the classical and beautiful character theory of finite groups. It does it by using some rudiments of the language of categories. Originally emerging from two courses offered at Peking University (PKU), primarily for third-year students, it is now better suited for graduate courses, and provides broader coverage than books that focus almost exclusively on groups. The book presents the basic tools, notions and theorems of character theory (including a new treatment of the control of fusion and isometries), and introduces readers to the categorical language at several levels. It includes and proves the major results on characteristic zero representations without any assumptions about the base field. The book includes a dedicated chapter on graded representations and applications of polynomial invariants of finite groups, and its closing chapter addresses the more recent notion of the Drinfeld double of a finite group and the corresponding representation of GL_2(Z).

  3. Strategies to balance covalent and non-covalent biomolecule attachment within collagen-GAG biomaterials.

    Science.gov (United States)

    Pence, Jacquelyn C; Gonnerman, Emily A; Bailey, Ryan C; Harley, Brendan A C

    2014-09-01

    Strategies to integrate instructive biomolecular signals into a biomaterial are becoming increasingly complex and bioinspired. While a large majority of reports still use repeated treatments with soluble factors, this approach can be prohibitively costly and difficult to translate in vivo for applications where spatial control over signal presentation is necessary. Recent efforts have explored the use of covalent immobilization of biomolecules to the biomaterial, via both bulk (ubiquitous) as well as spatially-selective light-based crosslinking, as a means to both enhance stability and bioactivity. However, little is known about how processing conditions during immobilization impact the degree of unintended non-covalent interactions, or fouling, that takes place between the biomaterial and the biomolecule of interest. Here we demonstrate the impact of processing conditions for bulk carbodiimide (EDC) and photolithography-based benzophenone (BP) crosslinking on specific attachment vs. fouling of a model protein (Concanavalin A, ConA) within collagen-glycosaminoglycan (CG) scaffolds. Collagen source significantly impacts the selectivity of biomolecule immobilization. EDC crosslinking intensity and ligand concentration significantly impacted selective immobilization. For benzophenone photoimmobilization we observed that increased UV exposure time leads to increased ConA immobilization. Immobilization efficiency for both EDC and BP strategies was maximal at physiological pH. Increasing ligand concentration during immobilization process led to enhanced immobilization for EDC chemistry, no impact on BP immobilization, but significant increases in non-specific fouling. Given recent efforts to covalently immobilize biomolecules to a biomaterial surface to enhance bioactivity, improved understanding of the impact of crosslinking conditions on selective attachment versus non-specific fouling will inform the design of instructive biomaterials for applications across tissue

  4. Diradical character of some fluoranthenes

    Directory of Open Access Journals (Sweden)

    SVETLANA MARKOVIĆ

    2010-09-01

    Full Text Available It is shown that some Kekuléan fluoranthenes are diradicals and that their ground state is a triplet. In the energetically less favorable singlet state, these hydrocarbons also exhibit pronounced diradical character. The diradical character y of the compounds under investigation was estimated using the unrestricted symmetry-broken (yPUHF and complete active space (yNOON methods. It was found that the yPUHF values better reproduce the diradical character of the investigated hydrocarbons. It was shown that singly occupied molecular orbital (SOMO and SOMO-1 of a diradical structure occupy different parts of space with a small shared region, resulting in a spin density distribution over the entire molecule. The spatial diradical distribution in the singlet diradical structures was examined by inspecting the HOMOs and LUMOs for a and b spin electrons. It was shown that the a-HOMO and the b-LUMO (as well as the b-HOMO and the a-LUMO occupy practically the same part of space. In this way, there are no unpaired electrons in a singlet diradical structure, yet two of them occupy different parts of space, thus allowing the p-electrons to delocalize.

  5. Characteristics of enzyme hydrolyzing natural covalent bond between RNA and protein VPg of encephalomyocarditis virus

    International Nuclear Information System (INIS)

    Drygin, Yu.F.; Siyanova, E.Yu.

    1986-01-01

    The isolation and a preliminary characterization of the enzyme specifically hydrolyzing the phosphodiester bond between protein VPg and the RNA of encephalomyocarditis virus was the goal of the present investigation. The enzyme was isolated from a salt extract of Krebs II mouse ascites carcinoma cells by ion-exchange and affinity chromatography. It was found that the enzyme actually specifically cleaves the covalent bond between the RNA and protein, however, the isolation procedure does not free the enzyme from impurities which partially inhibit it. The enzyme cleaves the RNA-protein VPg complex of polio virus at a high rate, it is completely inactivated at 55 0 C, and is partially inhibited by EDTA

  6. Predominantly ligand guided non-covalently linked assemblies of ...

    Indian Academy of Sciences (India)

    JUBARAJ B BARUAH

    2018-05-12

    May 12, 2018 ... Abstract. Various non-covalently linked inorganic self-assemblies formed by the supramolecular interacting .... metal-organic frameworks.59 Inorganic chemists rou- ...... two-dimensional organic–inorganic layered perovskite.

  7. Molecular electrostatic potential analysis of non-covalent complexes

    Indian Academy of Sciences (India)

    Chemical Sciences and Technology Division and Academy of Scientific & Innovative Research (AcSIR), ... workers proposed the electrostatic-covalent model of hydrogen bonding. ..... tain degree of electron donation and acceptance occurs.

  8. Covalent and non-covalent chemical engineering of actin for biotechnological applications.

    Science.gov (United States)

    Kumar, Saroj; Mansson, Alf

    2017-11-15

    The cytoskeletal filaments are self-assembled protein polymers with 8-25nm diameters and up to several tens of micrometres length. They have a range of pivotal roles in eukaryotic cells, including transportation of intracellular cargoes (primarily microtubules with dynein and kinesin motors) and cell motility (primarily actin and myosin) where muscle contraction is one example. For two decades, the cytoskeletal filaments and their associated motor systems have been explored for nanotechnological applications including miniaturized sensor systems and lab-on-a-chip devices. Several developments have also revolved around possible exploitation of the filaments alone without their motor partners. Efforts to use the cytoskeletal filaments for applications often require chemical or genetic engineering of the filaments such as specific conjugation with fluorophores, antibodies, oligonucleotides or various macromolecular complexes e.g. nanoparticles. Similar conjugation methods are also instrumental for a range of fundamental biophysical studies. Here we review methods for non-covalent and covalent chemical modifications of actin filaments with focus on critical advantages and challenges of different methods as well as critical steps in the conjugation procedures. We also review potential uses of the engineered actin filaments in nanotechnological applications and in some key fundamental studies of actin and myosin function. Finally, we consider possible future lines of investigation that may be addressed by applying chemical conjugation of actin in new ways. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  9. Artificial Neural Network Based Optical Character Recognition

    OpenAIRE

    Vivek Shrivastava; Navdeep Sharma

    2012-01-01

    Optical Character Recognition deals in recognition and classification of characters from an image. For the recognition to be accurate, certain topological and geometrical properties are calculated, based on which a character is classified and recognized. Also, the Human psychology perceives characters by its overall shape and features such as strokes, curves, protrusions, enclosures etc. These properties, also called Features are extracted from the image by means of spatial pixel-...

  10. Understanding the Properties of Interactive Televised Characters

    Science.gov (United States)

    Claxton, Laura J.; Ponto, Katelyn C.

    2013-01-01

    Children's television programming frequently uses interactive characters that appear to directly engage the viewers. These characters encourage children to answer questions and perform actions to help the characters solve problems in the televised world. Children readily engage in these interactions; however, it is unclear why they do so. To…

  11. A Review of Virtual Character's Emotion Model

    Science.gov (United States)

    Liu, Zhen

    2008-11-01

    Emotional virtual characters are essential to digital entertainment, an emotion is related to virtual environment and a virtual character's inner variables, emotion model of virtual character is a hot topic in many fields, domain knowledge is very important for modeling emotion, and the current research of emotion expression in the world was also summarized, and some new research directions of emotion model are presented.

  12. Promoting Character Development through Coach Education

    Science.gov (United States)

    Power, F. Clark; Seroczynski, A. D.

    2015-01-01

    Can youth sports build character? Research suggests that the answer to this question leads to 2 further questions: (1) can youth sport coaches be effectively prepared to become character educators, and (2) can character education take place in today's competitive youth sport environment? (Bredemeier & Shields, 2006; Power, 2015; Power &…

  13. Data set for Tifinagh handwriting character recognition

    Directory of Open Access Journals (Sweden)

    Omar Bencharef

    2015-09-01

    Full Text Available The Tifinagh alphabet-IRCAM is the official alphabet of the Amazigh language widely used in North Africa [1]. It includes thirty-one basic letter and two letters each composed of a base letter followed by the sign of labialization. Normalized only in 2003 (Unicode [2], ICRAM-Tifinagh is a young character repertoire. Which needs more work on all levels. In this context we propose a data set for handwritten Tifinagh characters composed of 1376 image; 43 Image For Each character. The dataset can be used to train a Tifinagh character recognition system, or to extract the meaning characteristics of each character.

  14. Body Language Advanced 3D Character Rigging

    CERN Document Server

    Allen, Eric; Fong, Jared; Sidwell, Adam G

    2011-01-01

    Whether you're a professional Character TD or just like to create 3D characters, this detailed guide reveals the techniques you need to create sophisticated 3D character rigs that range from basic to breathtaking. Packed with step-by-step instructions and full-color illustrations, Body Language walks you through rigging techniques for all the body parts to help you create realistic and believable movements in every character you design. You'll learn advanced rigging concepts that involve MEL scripting and advanced deformation techniques and even how to set up a character pipeline.

  15. Handwritten Sindhi Character Recognition Using Neural Networks

    Directory of Open Access Journals (Sweden)

    Shafique Ahmed Awan

    2018-01-01

    Full Text Available OCR (OpticalCharacter Recognition is a technology in which text image is used to understand and write text by machines. The work on languages containing isolated characters such as German, English, French and others is at its peak. The OCR and ICR (Intelligent Character Recognition research in Sindhi script is currently at in starting stages and not sufficient work have been cited in this area even though Sindhi language is rich in culture and history. This paper presents one of the initial steps in recognizing Sindhi handwritten characters. The isolated characters of Sindhi script written by thesubjects have been recognized. The various subjects were asked to write Sindhi characters in unconstrained form and then the written samples were collected and scanned through a flatbed scanner. The scanned documents were preprocessedwith the help of binary conversion, removing noise by pepper noise and the lines were segmented with the help of horizontal profile technique. The segmented lines were used to extract characters from scanned pages.This character segmentation was done by vertical projection. The extracted characters have been used to extract features so that the characters can be classified easily. Zoning was used for the feature extraction technique. For the classification, neural network has been used. The recognized characters converted into editable text with an average accuracy of 85%.

  16. Marvel and DC Characters Inspired by Arachnids

    Directory of Open Access Journals (Sweden)

    Elidiomar Ribeiro Da-Silva

    2014-12-01

    Full Text Available This article compares arachnid-based Marvel and DC comics characters. The composition of a comic book character often has interesting ‘real-life’ influences. Given the strong connection between arachnids (especially spiders, scorpions and mites, all belonging to the zoological class 'Arachnida' and human beings it is not surprising that they have inspired many fictional characters. We recorded 84 Marvel Comics characters and 40 DC Comics characters, detailed in the dataset that accompanies the article (Da-Silva 2014. Most characters have been created recently, since the 1990s. Marvel has significantly more arachnid characters than DC. As for taxonomic classification, the characters were based mostly on spiders (zoological order 'Araneae'. Of the total characters, the majority are human beings, but an overwhelming number have at least some typical arachnid features. Villains (60.91% of total are significantly more numerous, considering the sum of the two publishers. Arachnids have bad reputation for being dangerous (Thorp and Woodson 1976; Ruppert and Barnes 1996. Since the public usually considers spiders, scorpions and mites “harmful” in general, we expected a larger contingent of villains. However, there was no statistical difference between the amount of villains and heroes in Marvel characters. It did not happen probably due to the success of one character: the Amazing Spider-Man.

  17. Degraded character recognition based on gradient pattern

    Science.gov (United States)

    Babu, D. R. Ramesh; Ravishankar, M.; Kumar, Manish; Wadera, Kevin; Raj, Aakash

    2010-02-01

    Degraded character recognition is a challenging problem in the field of Optical Character Recognition (OCR). The performance of an optical character recognition depends upon printed quality of the input documents. Many OCRs have been designed which correctly identifies the fine printed documents. But, very few reported work has been found on the recognition of the degraded documents. The efficiency of the OCRs system decreases if the input image is degraded. In this paper, a novel approach based on gradient pattern for recognizing degraded printed character is proposed. The approach makes use of gradient pattern of an individual character for recognition. Experiments were conducted on character image that is either digitally written or a degraded character extracted from historical documents and the results are found to be satisfactory.

  18. Character animation fundamentals developing skills for 2D and 3D character animation

    CERN Document Server

    Roberts, Steve

    2012-01-01

    Expand your animation toolkit and remain competitive in the industry with this leading resource for 2D and 3D character animation techniques. Apply the industry's best practices to your own workflows and develop 2D, 3D and hybrid characters with ease. With side by side comparisons of 2D and 3D character design, improve your character animation and master traditional principles and processes including weight and balance, timing and walks. Develop characters inspired by humans, birds, fish, snakes and four legged animals. Breathe life into your character and develop a characters personality w

  19. Synthetic biology character and impact

    CERN Document Server

    Pade, Christian; Wigger, Henning; Gleich, Arnim

    2015-01-01

    Synthetic Biology is already an object of intensive debate. However, to a great extent the discussion to date has been concerned with fundamental ethical, religious and philosophical questions. By contrast, based on an investigation of the field’s scientific and technological character, this book focuses on new functionalities provided by synthetic biology and explores the associated opportunities and risks. Following an introduction to the subject and a discussion of the most central paradigms and methodologies, the book provides an overview of the structure of this field of science and technology. It informs the reader about the current stage of development, as well as topical problems and potential opportunities in important fields of application. But not only the science itself is in focus. In order to investigate its broader impact, ecological as well as ethical implications will be considered, paving the way for a discussion of responsibilities in the context of a field at a transitional crossroads be...

  20. Theory and Applications of Covalent Docking in Drug Discovery: Merits and Pitfalls

    Directory of Open Access Journals (Sweden)

    Hezekiel Mathambo Kumalo

    2015-01-01

    Full Text Available he present art of drug discovery and design of new drugs is based on suicidal irreversible inhibitors. Covalent inhibition is the strategy that is used to achieve irreversible inhibition. Irreversible inhibitors interact with their targets in a time-dependent fashion, and the reaction proceeds to completion rather than to equilibrium. Covalent inhibitors possessed some significant advantages over non-covalent inhibitors such as covalent warheads can target rare, non-conserved residue of a particular target protein and thus led to development of highly selective inhibitors, covalent inhibitors can be effective in targeting proteins with shallow binding cleavage which will led to development of novel inhibitors with increased potency than non-covalent inhibitors. Several computational approaches have been developed to simulate covalent interactions; however, this is still a challenging area to explore. Covalent molecular docking has been recently implemented in the computer-aided drug design workflows to describe covalent interactions between inhibitors and biological targets. In this review we highlight: (i covalent interactions in biomolecular systems; (ii the mathematical framework of covalent molecular docking; (iii implementation of covalent docking protocol in drug design workflows; (iv applications covalent docking: case studies and (v shortcomings and future perspectives of covalent docking. To the best of our knowledge; this review is the first account that highlights different aspects of covalent docking with its merits and pitfalls. We believe that the method and applications highlighted in this study will help future efforts towards the design of irreversible inhibitors.

  1. Preventing disulfide bond formation weakens non-covalent forces among lysozyme aggregates.

    Directory of Open Access Journals (Sweden)

    Vijay Kumar Ravi

    Full Text Available Nonnative disulfide bonds have been observed among protein aggregates in several diseases like amyotrophic lateral sclerosis, cataract and so on. The molecular mechanism by which formation of such bonds promotes protein aggregation is poorly understood. Here in this work we employ previously well characterized aggregation of hen eggwhite lysozyme (HEWL at alkaline pH to dissect the molecular role of nonnative disulfide bonds on growth of HEWL aggregates. We employed time-resolved fluorescence anisotropy, atomic force microscopy and single-molecule force spectroscopy to quantify the size, morphology and non-covalent interaction forces among the aggregates, respectively. These measurements were performed under conditions when disulfide bond formation was allowed (control and alternatively when it was prevented by alkylation of free thiols using iodoacetamide. Blocking disulfide bond formation affected growth but not growth kinetics of aggregates which were ∼50% reduced in volume, flatter in vertical dimension and non-fibrillar in comparison to control. Interestingly, single-molecule force spectroscopy data revealed that preventing disulfide bond formation weakened the non-covalent interaction forces among monomers in the aggregate by at least ten fold, thereby stalling their growth and yielding smaller aggregates in comparison to control. We conclude that while constrained protein chain dynamics in correctly disulfide bonded amyloidogenic proteins may protect them from venturing into partial folded conformations that can trigger entry into aggregation pathways, aberrant disulfide bonds in non-amyloidogenic proteins (like HEWL on the other hand, may strengthen non-covalent intermolecular forces among monomers and promote their aggregation.

  2. A covalent attraction between two molecular cation TTF·~+

    Institute of Scientific and Technical Information of China (English)

    WANG FangFang; WANG Yi; WANG BingQiang; WANG YinFeng; MA Fang; Li ZhiRu

    2009-01-01

    The optimized structure of the tetrathiafulvalence radical-cation dimer (TTF·~+-TTF·~+) with all-real frequencies is obtained at MP2/6-311G level,which exhibits the attraction between two molecular cation TTF·~+.The new attraction interaction is a 20-center-2-electron intermolecular covalent π/π bonding with a telescope shape.The covalent π/π bonding has the bonding energy of about-21 kcal·mol~(-1) and is concealed by the Coulombic repulsion between two TTF·~+ cations.This intermolecular covalent attraction also influences the structure of the TTF·~+ subunit,I.e.,its molecular plane is bent by an angle θ=5.6°.This work provides new knowledge on intermolecular interaction.

  3. A covalent attraction between two molecular cation TTF·~+

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    The optimized structure of the tetrathiafulvalence radical-cation dimer(TTF·+-TTF·+) with all-real frequencies is obtained at MP2/6-311G level,which exhibits the attraction between two molecular cation TTF·+.The new attraction interaction is a 20-center-2-electron intermolecular covalent π /π bonding with a telescope shape.The covalent π /π bonding has the bonding energy of about -21 kcal·mol-1 and is concealed by the Coulombic repulsion between two TTF·+ cations.This intermolecular covalent attraction also influences the structure of the TTF·+ subunit,i.e.,its molecular plane is bent by an angle θ=5.6°.This work provides new knowledge on intermolecular interaction.

  4. Covalent modification and exfoliation of graphene oxide using ferrocene

    Science.gov (United States)

    Avinash, M. B.; Subrahmanyam, K. S.; Sundarayya, Y.; Govindaraju, T.

    2010-09-01

    Large scale preparation of single-layer graphene and graphene oxide is of great importance due to their potential applications. We report a simple room temperature method for the exfoliation of graphene oxide using covalent modification of graphene oxide with ferrocene to obtain single-layer graphene oxide sheets. The samples were characterized by FESEM, HRTEM, AFM, EDAX, FT-IR, Raman and Mössbauer spectroscopic studies. HRTEM micrograph of the covalently modified graphene oxide showed increased interlayer spacing of ~2.4 nm due to ferrocene intercalation. The presence of single-layer graphene oxide sheets were confirmed by AFM studies. The covalently modified ferrocene-graphene oxide composite showed interesting magnetic behavior.Large scale preparation of single-layer graphene and graphene oxide is of great importance due to their potential applications. We report a simple room temperature method for the exfoliation of graphene oxide using covalent modification of graphene oxide with ferrocene to obtain single-layer graphene oxide sheets. The samples were characterized by FESEM, HRTEM, AFM, EDAX, FT-IR, Raman and Mössbauer spectroscopic studies. HRTEM micrograph of the covalently modified graphene oxide showed increased interlayer spacing of ~2.4 nm due to ferrocene intercalation. The presence of single-layer graphene oxide sheets were confirmed by AFM studies. The covalently modified ferrocene-graphene oxide composite showed interesting magnetic behavior. Electronic supplementary information (ESI) available: Magnetic data; AFM images; TEM micrographs; and Mössbauer spectroscopic data. See DOI: 10.1039/c0nr00024h

  5. Covalent and non-covalent curcumin loading in acid-responsive polymeric micellar nanocarriers

    Science.gov (United States)

    Gao, Min; Chen, Chao; Fan, Aiping; Zhang, Ju; Kong, Deling; Wang, Zheng; Zhao, Yanjun

    2015-07-01

    Poor aqueous solubility, potential degradation, rapid metabolism and elimination lead to low bioavailability of pleiotropic impotent curcumin. Herein, we report two types of acid-responsive polymeric micelles where curcumin was encapsulated via both covalent and non-covalent modes for enhanced loading capacity and on-demand release. Biodegradable methoxy poly(ethylene glycol)-poly(lactic acid) copolymer (mPEG-PLA) was conjugated with curcumin via a hydrazone linker, generating two conjugates differing in architecture (single-tail versus double-tail) and free curcumin was encapsulated therein. The two micelles exhibited similar hydrodynamic size at 95 ± 3 nm (single-tail) and 96 ± 3 nm (double-tail), but their loading capacities differed significantly at 15.0 ± 0.5% (w/w) (single-tail) and 4.8 ± 0.5% (w/w) (double-tail). Under acidic sink conditions (pH 5.0 and 6.0), curcumin displayed a faster release from the single-tail nanocarrier, which was correlated to a low IC50 of 14.7 ± 1.6 (μg mL-1) compared to the value of double-tail micelle (24.9 ± 1.3 μg mL-1) in HeLa cells. The confocal imaging and flow cytometry analysis demonstrated a superior capability of single-tail micelle for intracellular curcumin delivery, which was a consequence of the higher loading capacity and lower degree of mPEG surface coverage. In conclusion, the dual loading mode is an effective means to increase the drug content in the micellar nanocarriers whose delivery efficiency is highly dependent on its polymer-drug conjugate architecture. This strategy offers an alternative nanoplatform for intracellularly delivering impotent hydrophobic agents (i.e. curcumin) in an efficient stimuli-triggered way, which is valuable for the enhancement of curcumin’s efficacy in managing a diverse range of disorders.

  6. Covalent and non-covalent curcumin loading in acid-responsive polymeric micellar nanocarriers

    International Nuclear Information System (INIS)

    Gao, Min; Chen, Chao; Fan, Aiping; Wang, Zheng; Zhao, Yanjun; Zhang, Ju; Kong, Deling

    2015-01-01

    Poor aqueous solubility, potential degradation, rapid metabolism and elimination lead to low bioavailability of pleiotropic impotent curcumin. Herein, we report two types of acid-responsive polymeric micelles where curcumin was encapsulated via both covalent and non-covalent modes for enhanced loading capacity and on-demand release. Biodegradable methoxy poly(ethylene glycol)-poly(lactic acid) copolymer (mPEG-PLA) was conjugated with curcumin via a hydrazone linker, generating two conjugates differing in architecture (single-tail versus double-tail) and free curcumin was encapsulated therein. The two micelles exhibited similar hydrodynamic size at 95 ± 3 nm (single-tail) and 96 ± 3 nm (double-tail), but their loading capacities differed significantly at 15.0 ± 0.5% (w/w) (single-tail) and 4.8 ± 0.5% (w/w) (double-tail). Under acidic sink conditions (pH 5.0 and 6.0), curcumin displayed a faster release from the single-tail nanocarrier, which was correlated to a low IC_5_0 of 14.7 ± 1.6 (μg mL"−"1) compared to the value of double-tail micelle (24.9 ± 1.3 μg mL"−"1) in HeLa cells. The confocal imaging and flow cytometry analysis demonstrated a superior capability of single-tail micelle for intracellular curcumin delivery, which was a consequence of the higher loading capacity and lower degree of mPEG surface coverage. In conclusion, the dual loading mode is an effective means to increase the drug content in the micellar nanocarriers whose delivery efficiency is highly dependent on its polymer–drug conjugate architecture. This strategy offers an alternative nanoplatform for intracellularly delivering impotent hydrophobic agents (i.e. curcumin) in an efficient stimuli-triggered way, which is valuable for the enhancement of curcumin’s efficacy in managing a diverse range of disorders. (paper)

  7. Building innovative and creative character through mathematics

    Science.gov (United States)

    Suyitno, Hardi; Suyitno, Amin

    2018-03-01

    21st century is predicted as the century with rapid development in all aspects of life. People require creative and innovative character to exist. Specifically, mathematics has been given to students from the kindergarten until the middle school. Thus, building character through mathematics should begin since the early age. The problem is how to build creative and innovative character through mathematics education? The goal expected from this question is to build innovative and creative characters to face the challenges of the 21st century. This article discusses the values of mathematics, the values in mathematics education, innovative and creative character, and the integration of these values in teaching mathematics that support the innovative and creative character building, and applying the values in structurely programmed, measurable, and applicable learning activities.

  8. Construction of covalently coupled, concatameric dimers of 7TM receptors

    DEFF Research Database (Denmark)

    Terpager, Marie; Scholl, D Jason; Kubale, Valentina

    2009-01-01

    -Ala repeats flanked by flexible spacers and positively charged residues to ensure correct inside-out orientation plus an extracellular HA-tag to construct covalently coupled dimers of 7TM receptors. Such 15 TM concatameric homo- and heterodimers of the beta(2)-adrenergic and the NK(1) receptors, which...... for either of the protomers, which was not observed upon simple coexpression of the two receptors. It is concluded that covalently joined 7TM receptor dimers with surprisingly normal receptor properties can be constructed with use of an artificial transmembrane connector, which perhaps can be used to fuse...

  9. On the character of consciousness

    Directory of Open Access Journals (Sweden)

    Arto eAnnila

    2016-03-01

    Full Text Available The human brain is a particularly demanding system to infer its nature from observations. Thus, there is on one hand plenty of room for theorizing and on the other hand a pressing need for a rigorous theory. We apply statistical mechanics of open systems to describe the brain as a hierarchical system in consuming free energy in least time. This holistic tenet accounts for cellular metabolism, neuronal signaling, cognitive processes all together or any other process by a formal equation of motion that extends down to the ultimate precision of one quantum of action. According to this general thermodynamic theory cognitive processes are no different by their operational and organizational principle from other natural processes. Cognition too will emerge and evolve along path-dependent and non-determinate trajectories by consuming free energy in least time to attain thermodynamic balance within the nervous system itself and with its surrounding systems. Specifically, consciousness can be ascribed to a natural process that integrates various neural networks for coherent consumption of free energy, i.e., for meaningful deeds. The whole hierarchy of integrated systems can be formally summed up to thermodynamic entropy. The holistic tenet provides insight to the character of consciousness also by acknowledging awareness in other systems at other levels of nature’s hierarchy.

  10. Universal Partial Words over Non-Binary Alphabets

    OpenAIRE

    Goeckner, Bennet; Groothuis, Corbin; Hettle, Cyrus; Kell, Brian; Kirkpatrick, Pamela; Kirsch, Rachel; Solava, Ryan

    2016-01-01

    Chen, Kitaev, M\\"{u}tze, and Sun recently introduced the notion of universal partial words, a generalization of universal words and de Bruijn sequences. Universal partial words allow for a wild-card character $\\diamond$, which is a placeholder for any letter in the alphabet. We settle and strengthen conjectures posed in the same paper where this notion was introduced. For non-binary alphabets, we show that universal partial words have periodic $\\diamond$ structure and are cyclic, and we give ...

  11. Covalent microcontact printing of proteins fro cell patterning

    NARCIS (Netherlands)

    Rozkiewicz, D.I.; Kraan, Yvonne M.; Werten, Marc W.T.; de Wolf, Frits A.; Subramaniam, Vinod; Ravoo, B.J.; Reinhoudt, David

    2006-01-01

    We describe a straightforward approach to the covalent immobilization of cytophilic proteins by microcontact printing, which can be used to pattern cells on substrates. Cytophilic proteins are printed in micropatterns on reactive self-assembled monolayers by using imine chemistry. An

  12. Capillary electrophoresis of covalently functionalized single-chirality carbon nanotubes.

    Science.gov (United States)

    He, Pingli; Meany, Brendan; Wang, Chunyan; Piao, Yanmei; Kwon, Hyejin; Deng, Shunliu; Wang, YuHuang

    2017-07-01

    We demonstrate the separation of chirality-enriched single-walled carbon nanotubes (SWCNTs) by degree of surface functionalization using high-performance CE. Controlled amounts of negatively charged and positively charged functional groups were attached to the sidewall of chirality-enriched SWCNTs through covalent functionalization using 4-carboxybenzenediazonium tetrafluoroborate or 4-diazo-N,N-diethylaniline tetrafluoroborate, respectively. Surfactant- and pH-dependent studies confirmed that under conditions that minimized ionic screening effects, separation of these functionalized SWCNTs was strongly dependent on the surface charge density introduced through covalent surface chemistry. For both heterogeneous mixtures and single-chirality-enriched samples, covalently functionalized SWCNTs showed substantially increased peak width in electropherogram spectra compared to nonfunctionalized SWCNTs, which can be attributed to a distribution of surface charges along the functionalized nanotubes. Successful separation of functionalized single-chirality SWCNTs by functional density was confirmed with UV-Vis-NIR absorption and Raman scattering spectroscopies of fraction collected samples. These results suggest a high degree of structural heterogeneity in covalently functionalized SWCNTs, even for chirality-enriched samples, and show the feasibility of applying CE for high-performance separation of nanomaterials based on differences in surface functional density. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. COVAL, Compound Probability Distribution for Function of Probability Distribution

    International Nuclear Information System (INIS)

    Astolfi, M.; Elbaz, J.

    1979-01-01

    1 - Nature of the physical problem solved: Computation of the probability distribution of a function of variables, given the probability distribution of the variables themselves. 'COVAL' has been applied to reliability analysis of a structure subject to random loads. 2 - Method of solution: Numerical transformation of probability distributions

  14. Covalent Attachment of Bent-Core Mesogens to Silicon Surfaces

    NARCIS (Netherlands)

    Scheres, L.; Achten, R.; Giesbers, M.; Smet, de L.; Arafat, A.; Sudhölter, E.J.R.; Marcelis, A.T.M.; Zuilhof, H.

    2009-01-01

    Two vinyl-terminated bent core-shaped liquid crystalline molecules that exhibit thermotropic antiferroelectric SmCPA phases have been covalently attached onto a hydrogen-terminated silicon(111) surface. The surface attachment was achieved via a mild procedure from a mesitylene solution, using

  15. Multi-step non-covalent pathways to supramolecular systems

    NARCIS (Netherlands)

    Hermans, T.M.

    2010-01-01

    The spontaneous organization of building blocks into ordered structures governed by non-covalent interactions, or self-assembly, is a commonly encountered pathway in nature to obtain functional materials. These materials often consist of many different components ordered into intricate structures.

  16. Covalent Functionalization of Carbon Nanotube by Tetrasubtituted Amino Manganese Phthalocyanine

    Institute of Scientific and Technical Information of China (English)

    Zheng Long YANG; Hong Zheng CHEN; Lei CAO; Han Yin LI; Mang WANG

    2004-01-01

    The multiwall carbon nanotube (MWCNT) bonded to 2, 9, 16, 23-tetraamino manganese phthalocyanine (TAMnPc) was obtained by covalent functionalization, and its chemical structure was characterized by TEM. The photoconductivity of single-layered photoreceptors, where MWCNT bonded by TAMnPc (MWCNT-b-TAMnPc) served as the charge generation material (CGM), was also studied.

  17. Double Dynamic Supramolecular Polymers of Covalent Oligo-Dynamers

    NARCIS (Netherlands)

    Schaeffer, Gaël; Buhler, Eric; Candau, Sauveur Jean; Lehn, Jean-Marie

    2013-01-01

    Double-dynamic polymers, incorporating both molecular and supramolecular dynamic features (“double dynamers”) have been generated, where these functions are present in a nonstoichiometric ratio in the main chain of the polymer. It has been achieved by (1) the formation of covalent oligo-dynamers in

  18. Covalent bindings in proteins following UV-C irradiation

    International Nuclear Information System (INIS)

    Diezel, W.; Meffert, H.; Soennichsen, N.; Reinicke, C.

    1980-01-01

    Following a UV-C irradiation of catalase cross-linked catalase subunits could be detected by sodium dodecylsulfate gel electrophoresis. The subunits of aldolase were not cross-linked. The origin of covalent bindings in the catalase molecule is suggested to be effected by a free radical chain reaction induced by the heme component of catalase after UV-C irradiation. (author)

  19. DIALOGUE AND CHARACTER CLASSIFICATION IN WOLE ...

    African Journals Online (AJOL)

    position, level of education, character and habits of a character are reflected in the speech .... Dictators are averse to any form of ... breaks out shouting slogans of praises of himself. ..... Task easier if I can get all the Obas settled before our.

  20. Character order processing in Chinese reading.

    Science.gov (United States)

    Gu, Junjuan; Li, Xingshan; Liversedge, Simon P

    2015-02-01

    We explored how character order information is encoded in isolated word processing or Chinese sentence reading in 2 experiments using a masked priming paradigm and a gaze-contingent display-change paradigm. The results showed that response latencies in the lexical decision task and reading times on the target word region were longer in the unrelated condition (the prime or the preview was unrelated with the target word) than the transposed-character condition (the prime or the preview was a transposition of the 2 characters of the target word), which were respectively longer than in the identity condition (the prime or preview was identical to the target word). These results show that character order is encoded at an early stage of processing in Chinese reading, but character position encoding was not strict. We also found that character order encoding was similar for single-morpheme and multiple-morpheme words, suggesting that morphemic status does not affect character order encoding. The current results represent an early contribution to our understanding of character order encoding during Chinese reading.

  1. Aristotelian versus Virtue Ethical Character Education

    Science.gov (United States)

    Curren, Randall

    2016-01-01

    This article examines some central aspects of Kristján Kristjánsson's book, "Aristotelian Character Education," beginning with the claim that contemporary virtue ethics provides methodological, ontological, epistemological, and moral foundations for Aristotelian character education. It considers three different formulations of what…

  2. Relationships between Character Education and School Climate

    Science.gov (United States)

    Karaburk, Hasan

    2017-01-01

    The purpose of this study was to explore the relationships between character education and school climate based on the lived experiences and beliefs of teachers. The research was conducted in a public middle school to explore understandings and beliefs of teachers about character education and its perceived impact on school climate. Social…

  3. A database application for wilderness character monitoring

    Science.gov (United States)

    Ashley Adams; Peter Landres; Simon Kingston

    2012-01-01

    The National Park Service (NPS) Wilderness Stewardship Division, in collaboration with the Aldo Leopold Wilderness Research Institute and the NPS Inventory and Monitoring Program, developed a database application to facilitate tracking and trend reporting in wilderness character. The Wilderness Character Monitoring Database allows consistent, scientifically based...

  4. Developing Individual and Team Character in Sport

    Science.gov (United States)

    Gaines, Stacey A.

    2012-01-01

    The idea that participation in sport builds character is a long-standing one. Advocates of sport participation believe that sport provides an appropriate context for the learning of social skills such as cooperation and the development of prosocial behavior (Weiss, Smith, & Stuntz, 2008). Research in sport regarding character development has…

  5. On character amenability of semigroup algebras | Maepa ...

    African Journals Online (AJOL)

    We study the character amenability of semigroup algebras. We work on general semigroups and certain semigroups such as inverse semigroups with a nite number of idempotents, inverse semigroups with uniformly locally nite idempotent set, Brandt and Rees semigroup and study the character amenability of the ...

  6. First Course in Japanese: Character Workbook.

    Science.gov (United States)

    Niwa, Tamako

    This character workbook is an introduction to Japanese writing designed to be used in conjunction with Parts One and Two of this introductory course in Japanese. All the "hiragana", several "katakana", and 88 Japanese characters are introduced in this text. The workbook, consisting of 30 lessons, is divided into three parts.…

  7. Landscape Character of Pongkor Mining Ecotourism Area

    Science.gov (United States)

    Kusumoarto, A.; Gunawan, A.; Machfud; Hikmat, A.

    2017-10-01

    Pongkor Mining Ecotourism Area has a diverse landscape character as a potential landscape resources for the development of ecotourism destination. This area is part of the Mount of Botol Resort, Halimun Salak National Park (HSNP). This area also has a fairly high biodiversity. This study aims to identify and analysis the category of landscape character in the Pongkor Mining Ecotourism Area for the development of ecotourism destination. This study used a descriptive approach through field surveys and interviews, was carried out through two steps : 1) identify the landscape character, and 2) analysis of the landscape character. The results showed that in areas set aside for ecotourism destination in Pongkor Mining, landscape character category scattered forests, tailing ponds, river, plain, and the built environment. The Category of landscape character most dominant scattered in the area is forest, here is the river, plain, tailing ponds, the built environment, and plain. The landscape character in a natural environment most preferred for ecotourism activities. The landscape character that spread in the natural environment and the built environment is a potential that must be protected and modified such as elimination of incongruous element, accentuation of natural form, alteration of the natural form, intensification and enhanced visual quality intensively to be developed as a ecotourism destination area.

  8. Do Rural Schools Need Character Education?

    Science.gov (United States)

    Reynolds, Janice Carner

    Studies suggest that the challenge of violence in public schools can be met through character education, whether by providing a school culture in which core values are practiced or some form of moral training (indoctrination). To assess the need for character education in rural schools, small-school superintendents and board members in central…

  9. Moral character effects in endorser perception

    Directory of Open Access Journals (Sweden)

    Chang Joseph W.

    2017-06-01

    Full Text Available This research consists of two experimental studies investigating the influence of moral character on endorser perception, and the influence of perceiver characteristics on tarnished endorser perception and brand evaluations. Perceiver characteristics are discussed from the perspectives of dispositional tendency, innate moral intuitions and self-location. The first study compared the influences of moral character and warmth on endorser perception. The second study examined the impact of perceiver characteristics on tarnished endorsers and brand evaluations. The findings reveal that moral character is more influential than warmth on endorser evaluations. Tarnished endorsers with immoral character exert more negative influence than tarnished endorsers with coldness character on brand evaluations. Innate moral intuitions and self-location moderate brand evaluations. High-morality consumers and heart-locators are more vulnerable than low-morality and brain-locators to the brands endorsed by tarnished endorsers, respectively.

  10. Character Education and Students Social Behavior

    Directory of Open Access Journals (Sweden)

    Syamsu A. Kamaruddin

    2012-09-01

    Full Text Available

    In an educational environment, in the form of character education program has been done both formally and informally. It's intended as one of the supporting ideas for follow-up in the form of design activities. Character education should basically refers to the vision and mission of the institution concerned. It shows the orientation of the two things in the character of the students are: aspects of human character and individual learners hallmark institution. In this paper, these two aspects is the author trying to ideas by referring to some other writings. The end result, the authors expect the birth of a design patent as early referral to spearhead a character development program learners.

  11. A Missing Piece of the Contemporary Character Education Puzzle: The Individualisation of Moral Character

    Science.gov (United States)

    Chen, Yi-Lin

    2013-01-01

    The different sorts of virtuous people who display various virtues to a remarkable degree have brought the issue of individualisation of moral character to the forefront. It signals a more personal dimension of character development which is notoriously ignored in the current discourse on character education. The case is made that since in…

  12. Character Recognition Using Genetically Trained Neural Networks

    Energy Technology Data Exchange (ETDEWEB)

    Diniz, C.; Stantz, K.M.; Trahan, M.W.; Wagner, J.S.

    1998-10-01

    Computationally intelligent recognition of characters and symbols addresses a wide range of applications including foreign language translation and chemical formula identification. The combination of intelligent learning and optimization algorithms with layered neural structures offers powerful techniques for character recognition. These techniques were originally developed by Sandia National Laboratories for pattern and spectral analysis; however, their ability to optimize vast amounts of data make them ideal for character recognition. An adaptation of the Neural Network Designer soflsvare allows the user to create a neural network (NN_) trained by a genetic algorithm (GA) that correctly identifies multiple distinct characters. The initial successfid recognition of standard capital letters can be expanded to include chemical and mathematical symbols and alphabets of foreign languages, especially Arabic and Chinese. The FIN model constructed for this project uses a three layer feed-forward architecture. To facilitate the input of characters and symbols, a graphic user interface (GUI) has been developed to convert the traditional representation of each character or symbol to a bitmap. The 8 x 8 bitmap representations used for these tests are mapped onto the input nodes of the feed-forward neural network (FFNN) in a one-to-one correspondence. The input nodes feed forward into a hidden layer, and the hidden layer feeds into five output nodes correlated to possible character outcomes. During the training period the GA optimizes the weights of the NN until it can successfully recognize distinct characters. Systematic deviations from the base design test the network's range of applicability. Increasing capacity, the number of letters to be recognized, requires a nonlinear increase in the number of hidden layer neurodes. Optimal character recognition performance necessitates a minimum threshold for the number of cases when genetically training the net. And, the

  13. High covalence in CuSO4 and the radicalization of sulfate: an X-ray absorption and density functional study.

    Science.gov (United States)

    Szilagyi, Robert K; Frank, Patrick; DeBeer George, Serena; Hedman, Britt; Hodgson, Keith O

    2004-12-27

    Sulfur K-edge X-ray absorption spectroscopy (XAS) of anhydrous CuSO(4) reveals a well-resolved preedge transition feature at 2478.8 eV that has no counterpart in the XAS spectra of anhydrous ZnSO(4) or copper sulfate pentahydrate. Similar but weaker preedge features occur in the sulfur K-edge XAS spectra of [Cu(itao)SO(4)] (2478.4 eV) and [Cu[(CH(3))(6)tren]SO(4)] (2477.7 eV). Preedge features in the XAS spectra of transition metal ligands are generally attributed to covalent delocalization of a metal d-orbital hole into a ligand-based orbital. Copper L-edge XAS of CuSO(4) revealed that 56% of the Cu(II) 3d hole is delocalized onto the sulfate ligand. Hybrid density functional calculations on the two most realistic models of the covalent delocalization pathways in CuSO(4) indicate about 50% electron delocalization onto the sulfate oxygen-based 2p orbitals; however, at most 14% of that can be found on sulfate sulfur. Both experimental and computational results indicated that the high covalence of anhydrous CuSO(4) has made sulfate more like the radical monoanion, inducing an extensive mixing and redistribution of sulfur 3p-based unoccupied orbitals to lower energy in comparison to sulfate in ZnSO(4). It is this redistribution, rather than a direct covalent interaction between Cu(II) and sulfur, that is the origin of the observed sulfur XAS preedge feature. From pseudo-Voigt fits to the CuSO(4) sulfur K-edge XAS spectrum, a ground-state 3p character of 6% was quantified for the orbital contributing to the preedge transition, in reasonable agreement with the DFT calculation. Similar XAS fits indicated 2% sulfur 3p character for the preedge transition orbitals in [Cu(itao)SO(4)] and [Cu[(CH(3))(6)tren]SO(4)]. The covalent radicalization of ligands similar to sulfate, with consequent energy redistribution of the virtual orbitals, represents a new mechanism for the induction of ligand preedge XAS features. The high covalence of the Cu sites in CuSO(4) was found to be

  14. Video Game Characters. Theory and Analysis

    Directory of Open Access Journals (Sweden)

    Felix Schröter

    2014-06-01

    Full Text Available This essay develops a method for the analysis of video game characters based on a theoretical understanding of their medium-specific representation and the mental processes involved in their intersubjective construction by video game players. We propose to distinguish, first, between narration, simulation, and communication as three modes of representation particularly salient for contemporary video games and the characters they represent, second, between narrative, ludic, and social experience as three ways in which players perceive video game characters and their representations, and, third, between three dimensions of video game characters as ‘intersubjective constructs’, which usually are to be analyzed not only as fictional beings with certain diegetic properties but also as game pieces with certain ludic properties and, in those cases in which they function as avatars in the social space of a multiplayer game, as representations of other players. Having established these basic distinctions, we proceed to analyze their realization and interrelation by reference to the character of Martin Walker from the third-person shooter Spec Ops: The Line (Yager Development 2012, the highly customizable player-controlled characters from the role-playing game The Elder Scrolls V: Skyrim (Bethesda 2011, and the complex multidimensional characters in the massively multiplayer online role-playing game Star Wars: The Old Republic (BioWare 2011-2014.

  15. Rare Examples of Fe(IV) Alkyl-Imide Migratory Insertions: Impact of Fe-C Covalency in (Me2IPr)Fe(═NAd)R2 (R = neoPe, 1-nor).

    Science.gov (United States)

    Jacobs, Brian P; Wolczanski, Peter T; Jiang, Quan; Cundari, Thomas R; MacMillan, Samantha N

    2017-09-06

    The iron(IV) imide complexes, (Me 2 IPr)-R 2 Fe=NAd (R = neo Pe (3a), 1-nor (3b)) undergo migratory insertion to iron(II) amides (Me 2 IPr)RFe{NR(Ad)} (R = neo Pe (4a), 1-nor (4b)) without evidence of imidyl or free nitrene character. By increasing the field strength about iron, odd-electron reactivity was circumvented via increased covalency.

  16. A structural query system for Han characters

    DEFF Research Database (Denmark)

    Skala, Matthew

    2016-01-01

    The IDSgrep structural query system for Han character dictionaries is presented. This dictionary search system represents the spatial structure of Han characters using Extended Ideographic Description Sequences (EIDSes), a data model and syntax based on the Unicode IDS concept. It includes a query...... language for EIDS databases, with a freely available implementation and format translation from popular third-party IDS and XML character databases. The system is designed to suit the needs of font developers and foreign language learners. The search algorithm includes a bit vector index inspired by Bloom...... filters to support faster query operations. Experimental results are presented, evaluating the effect of the indexing on query performance....

  17. Submatrices of character tables and basic sets

    DEFF Research Database (Denmark)

    Bessenrodt, Christine; Olsson, Jørn Børling

    2012-01-01

    In this investigation of character tables of nite groups we study basic sets and associated representation theoretic data for complementary sets of conjugacy lasses. For the symmetric groups we nd unexpected properties of characters on restricted sets of conjugacy classes, like beautiful...... combinatorial determinant formulae for submatrices of the character table and Cartan matrices with respect to basic sets; we observe that similar phenomena occur for the transition matrices between power sum symmetric functions to bounded partitions and the k-Schur functions dened by Lapointe and Morse...

  18. On Hemingway’s Literary Characters

    Directory of Open Access Journals (Sweden)

    Maria-Miruna Ciocoi-Pop

    2013-01-01

    Full Text Available The present paper is a brief outline of Hemingway’s characters and the way in which they correspond to the author himself. It is known for a fact that Hemingway evinced a tendency to imitate his characters when they were coming to grips with diverse situations. Thus I have tried to briefly pinpoint the fading boundaries between reality and imagination in his work. By doing so, I have focused on both male and female characters, underlining the major dissimilarities between these two categories, as well as their main features.

  19. EPR-spin probe studies of model polymers: separation of covalent cross-linking effects from hydrogen bonding effects in swelled Argonne Premium Coal samples

    Energy Technology Data Exchange (ETDEWEB)

    Spears, D.R.; Sady, W.; Tucker, D.; Kispert, L.D. (University of Alabama, Tuscaloosa, AL (United States). Chemistry Dept.)

    The swelling behaviour of 2-12% cross-linked polystyrene-divinylbenzene (PSDVB) copolymers was examined by an EPR-spin probe technique. It was observed that the mechanism of spin probe inclusion was the intercalation into the matrix rather than diffusion into the pores. The disruption of van der Waals forces between adjacent aromatic rings appeared to be the primary mechanism for pyridine swelling of PSDVB. By comparing the data to results from coal swelling studies it was also inferred that the extent of hydrogen bonding in coal will have a much greater impact on its swelling properties than its covalently cross-linked character. 24 refs., 6 figs.

  20. Binding matter with antimatter: the covalent positron bond.

    Science.gov (United States)

    Charry, Jorge Alfonso; Varella, Marcio T Do N; Reyes, Andrés

    2018-05-16

    We report sufficient theoretical evidence of the energy stability of the e⁺H₂²⁻ molecule, formed by two H⁻ anions and one positron. Analysis of the electronic and positronic densities of the latter compound undoubtedly points out the formation of a positronic covalent bond between the otherwise repelling hydride anions. The lower limit for the bonding energy of the e⁺H₂²⁻ molecule is 74 kJ/mol (0.77 eV), accounting for the zero-point vibrational correction. The formation of a non electronic covalent bond is fundamentally distinct from positron attachment to stable molecules, as the latter process is characterized by a positron affinity, analogous to the electron affinity. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. Temperature Scanning Stress Relaxation of an Autonomous Self-Healing Elastomer Containing Non-Covalent Reversible Network Junctions

    Directory of Open Access Journals (Sweden)

    Amit Das

    2018-01-01

    Full Text Available In this work, we report about the mechanical relaxation characteristics of an intrinsically self-healable imidazole modified commercial rubber. This kind of self-healing rubber was prepared by melt mixing of 1-butyl imidazole with bromo-butyl rubber (bromine modified isoprene-isobutylene copolymer, BIIR. By this melt mixing process, the reactive allylic bromine of bromo-butyl rubber was converted into imidazole bromide salt. The resulting development of an ionic character to the polymer backbone leads to an ionic association of the groups which ultimately results to the formation of a network structure of the rubber chains. The modified BIIR thus behaves like a robust crosslinked rubber and shows unusual self-healing properties. The non-covalent reversible network has been studied in detail with respect to stress relaxation experiments, scanning electron microscopic and X-ray scattering.

  2. Two supramolecular complexes based on polyoxometalates and Co-EDTA units via covalent connection or non-covalent interaction

    Energy Technology Data Exchange (ETDEWEB)

    Teng, Chunlin; Xiao, Hanxi [Key Laboratory of Theoretical Organic Chemistry and Functional Molecule for Ministry of Education, Hunan University of Science and Technology, Xiangtan 411201 (China); Cai, Qing [Chemistry Department, City University of New York, New York, NY 10016 (United States); Tang, Jianting; Cai, Tiejun [Key Laboratory of Theoretical Organic Chemistry and Functional Molecule for Ministry of Education, Hunan University of Science and Technology, Xiangtan 411201 (China); Deng, Qian, E-mail: dengqian10502@163.com [Key Laboratory of Theoretical Organic Chemistry and Functional Molecule for Ministry of Education, Hunan University of Science and Technology, Xiangtan 411201 (China)

    2016-11-15

    Two new 3D network organic-inorganic hybrid supramolecular complexes ([Na{sub 6}(CoEDTA){sub 2}(H{sub 2}O){sub 13}]·(H{sub 2}SiW{sub 12}O{sub 40})·xH{sub 2}O)n (1) and [CoH{sub 4}EDTA(H{sub 2}O)]{sub 2}(SiW{sub 12}O{sub 40})·15H{sub 2}O (2) (H{sub 4}EDTA=Ethylenediamine tetraacetic acid) have been successfully synthesized by solution method, and characterized by infrared spectrum (IR), thermogravimetric-differential thermal analysis (TG-DTA), cyclic voltammetry (CV) and single{sup −}crystal X-ray diffraction (XRD). Both of the complexes are the supramolecules, but with different liking mode, they are two representative models of supramolecule. complex (1) is a 3D infinite network supramolecular coordination polymer with a rare multi-metal sturcture of sodium-cobalt-containing, which is mainly linked through coordinate-covalent bonds. While complex (2) is normal supramolecule, which linked by non-covalent interactions, such as H-bonding interaction, electrostatic interaction and van der waals force. Both of complex (1) and (2) exhibit good catalytic activities for catalytic oxidation of methanol, when the initial concentration of methanol is 3.0 g m{sup −3}, flow rate is 10 mL min{sup −1}, and the quality of catalyst is 0.2 g, for complex (1) and complex (2) the maximum elimination rates of methanol are 85% (150 °C) and 92% (120 °C), respectively. - Graphical abstract: Two new organic-inorganic hybrid supramolecular complexes based on Co-EDTA, and Keggin polyanions have been successfully synthesized with different pH value by solution method. They are attributed to two representative models of supramolecule. Complex(1) is an infinite coordination polymer with a rare multi-metal sturcture of sodium-cobalt-containing, which is mainly linked through covalent bonds. Complex (2) is a normal supramolecule, which linked by non-covalent interactions of H-bonding interaction, electrostatic interaction and van der waals force. - Highlights: • Two supramolecules

  3. Building high-coverage monolayers of covalently bound magnetic nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Williams, Mackenzie G.; Teplyakov, Andrew V., E-mail: andrewt@udel.edu

    2016-12-01

    Graphical abstract: - Highlights: • A method for forming a layer of covalently bound nanoparticles is offered. • A nearly perfect monolayer of covalently bound magnetic nanoparticles was formed on gold. • Spectroscopic techniques confirmed covalent binding by the “click” reaction. • The influence of the functionalization scheme on surface coverage was investigated. - Abstract: This work presents an approach for producing a high-coverage single monolayer of magnetic nanoparticles using “click chemistry” between complementarily functionalized nanoparticles and a flat substrate. This method highlights essential aspects of the functionalization scheme for substrate surface and nanoparticles to produce exceptionally high surface coverage without sacrificing selectivity or control over the layer produced. The deposition of one single layer of magnetic particles without agglomeration, over a large area, with a nearly 100% coverage is confirmed by electron microscopy. Spectroscopic techniques, supplemented by computational predictions, are used to interrogate the chemistry of the attachment and to confirm covalent binding, rather than attachment through self-assembly or weak van der Waals bonding. Density functional theory calculations for the surface intermediate of this copper-catalyzed process provide mechanistic insight into the effects of the functionalization scheme on surface coverage. Based on this analysis, it appears that steric limitations of the intermediate structure affect nanoparticle coverage on a flat solid substrate; however, this can be overcome by designing a functionalization scheme in such a way that the copper-based intermediate is formed on the spherical nanoparticles instead. This observation can be carried over to other approaches for creating highly controlled single- or multilayered nanostructures of a wide range of materials to result in high coverage and possibly, conformal filling.

  4. Preparation and characterization of two types of covalently immobilized amyloglucosidase

    Directory of Open Access Journals (Sweden)

    ZORAN VUJCIC

    2005-05-01

    Full Text Available Amyloglucosidase from A. niger was covalently immobilized onto poly (GMA-co-EGDMA by the glutaraldehyde and periodate method. The immobilization of amyloglucosidase after periodate oxidation gave a preparate with the highest specific activity reported so far on similar polymers. The obtained immobilized preparates show the same pH optimum, but a higher temperature optimum compared with the soluble enzyme. The kinetic parameters for the hydrolysis of soluble starch by free and both immobilized enzymes were determined.

  5. How jurors use and misuse character evidence.

    Science.gov (United States)

    Hunt, Jennifer S; Budesheim, Thomas Lee

    2004-04-01

    The Federal Rules of Evidence allow defendants to offer testimony about their good character, but that testimony can be impeached with cross-examination or a rebuttal witness. It is assumed that jurors use the defense's character evidence (CE) to form guilt and conviction judgments but use impeachment evidence only to assess the character witness's credibility. Two experiments tested these assumptions by presenting mock jurors with various forms of CE and impeachment. Participants made trait ratings for the character witness and defendant and guilt and conviction judgments. Positive CE did not affect guilt or conviction judgments, but cross-examination caused a backlash in which judgments were harsher than when no CE was given. Using path analysis, the authors tested a model of the process by which CE and impeachment affect defendant and witness impressions and guilt and conviction judgments. Implications for juror decision making are discussed.

  6. Molecular characters and recombinant expression of the ...

    African Journals Online (AJOL)

    user

    2011-03-07

    Mar 7, 2011 ... Full Length Research Paper. Molecular characters ... 1State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of .... Characterization and model building of the 3-D.

  7. Some Correlates of the Arab Character.

    Science.gov (United States)

    Moracco, John

    1983-01-01

    Describes cultural correlates of the Arab character in terms of family patterns, international relations, and implications for therapists and other human service personnel. Discusses the Bedouin influence and religious values and suggests that cultural stereotypes may restrict true understanding. (JAC)

  8. Alterations in subspecific characters of groundnut

    International Nuclear Information System (INIS)

    Mouli, C.; Patil, S.H.; Kale, D.M.

    1983-01-01

    Recombination of beneficial characters associated in the cultivars of groundnut (Arachis hypogaea, L.) belonging to the two subspecies hypogaea and fastigiata had little success in conventional breeding programme. The cultures of ssp. hypogaea have the desirable characters for the crop improvement viz; various growth habits, profuse branching, large pod, seed dormancy and stress tolerance. Sequential flowering, early maturity, compact fruiting habit and high kernel outturn are the other useful characters present in ssp. fastigiata cultures. Mutation research in a popular variety, Spanish Improved belonging to ssp. fastigiata led to the selection of various mutants. One among the mutants had large pod, a characteristic of hypogaea ssp. Hybridization among the mutants and improved cultivars as well as radiation treatment of selected cultures resulted in the isolation of cultures having not only combinations and alterations of characters in both subspecies, but also modifications. These cultures are classified into major groups and their significance in the groundnut improvement is discussed. (author)

  9. Brains with character: Reading and writing neuronarrative

    NARCIS (Netherlands)

    Yaczo, T.F.

    2015-01-01

    Brains with Character: Reading and Writing Neuronarrative tracks the concept of neuronarrative by analyzing the reciprocal and catalytic relationships between neuroscience and literary media. Crucial to understanding the contemporary stakes in these two cultural endeavors is how their relationships

  10. Covalently bound molecular states in beryllium and carbon isotopes

    International Nuclear Information System (INIS)

    Wolfram von, Oertzen; Hans-Gerhard, Bohlen; Wolfram von, Oertzen

    2003-01-01

    Nuclear clustering in N=Z nuclei has been studied since many decades. States close to the decay thresholds, as described by the Ikeda diagram, are of particular interest. Recent studies in loosely bound systems, as observed with neutron-rich nuclei has revived the interest in cluster structures in nuclei, with additional valence neutrons, which give rise to pronounced covalent molecular structures. The Beryllium isotopes represent the first example of such unique states in nuclear physics with extreme deformations. In the deformed shell model these are referred to as super- and hyper-deformation. These states can be described explicitly by molecular concepts, with neutrons in covalent binding orbits. Examples of recent experiments performed at the HMI-Berlin demonstrating the molecular structure of the rotational bands in Beryllium isotopes are presented. Further work on chain states (nuclear polymers) in the carbon isotopes is in progress, these are the first examples of deformed structures in nuclei with an axis ratio of 3:1. A threshold diagram with clusters bound via neutrons in covalent molecular configurations can be established, which can serve as a guideline for future work. (authors)

  11. Generation of covalently closed circular DNA of hepatitis B viruses via intracellular recycling is regulated in a virus specific manner.

    Directory of Open Access Journals (Sweden)

    Josef Köck

    Full Text Available Persistence of hepatitis B virus (HBV infection requires covalently closed circular (cccDNA formation and amplification, which can occur via intracellular recycling of the viral polymerase-linked relaxed circular (rc DNA genomes present in virions. Here we reveal a fundamental difference between HBV and the related duck hepatitis B virus (DHBV in the recycling mechanism. Direct comparison of HBV and DHBV cccDNA amplification in cross-species transfection experiments showed that, in the same human cell background, DHBV but not HBV rcDNA converts efficiently into cccDNA. By characterizing the distinct forms of HBV and DHBV rcDNA accumulating in the cells we find that nuclear import, complete versus partial release from the capsid and complete versus partial removal of the covalently bound polymerase contribute to limiting HBV cccDNA formation; particularly, we identify genome region-selectively opened nuclear capsids as a putative novel HBV uncoating intermediate. However, the presence in the nucleus of around 40% of completely uncoated rcDNA that lacks most if not all of the covalently bound protein strongly suggests a major block further downstream that operates in the HBV but not DHBV recycling pathway. In summary, our results uncover an unexpected contribution of the virus to cccDNA formation that might help to better understand the persistence of HBV infection. Moreover, efficient DHBV cccDNA formation in human hepatoma cells should greatly facilitate experimental identification, and possibly inhibition, of the human cell factors involved in the process.

  12. ECONOMIC ETHICS: APPLIED AND PROFESSIONAL CHARACTER

    Directory of Open Access Journals (Sweden)

    Ella Gordova

    2012-01-01

    Full Text Available In given article economic ethics are considered as set of norms of behavior of the businessman, the requirements shown by a cultural society to its style of work, to character of dialogue between participants of business, to their social shape. The conclusion becomes that economic ethics have applied character in relation to theoretical, to obschenormativnoy ethics, hence, represent section of applied ethics. On the other hand, the specific standard maintenance characterizes economic ethics as ethics professional.

  13. A STUDY ON OPTICAL CHARACTER RECOGNITION TECHNIQUES

    OpenAIRE

    Narendra Sahu; Manoj Sonkusare

    2018-01-01

    Optical Character Recognition (OCR) is the process which enables a system to without human intervention identifies the scripts or alphabets written into the users’ verbal communication. Optical Character identification has grown to be individual of the mainly flourishing applications of knowledge in the field of pattern detection and artificial intelligence. In our survey we study on the various OCR techniques. In this paper we resolve and examine the hypothetical and numerical models of Opti...

  14. Use of Splines in Handwritten Character Recognition

    OpenAIRE

    Sunil Kumar; Gopinath S,; Satish Kumar; Rajesh Chhikara

    2010-01-01

    Handwritten Character Recognition is software used to identify the handwritten characters and receive and interpret intelligible andwritten input from sources such as manuscript documents. The recent past several years has seen the development of many systems which are able to simulate the human brain actions. Among the many, the neural networks and the artificial intelligence are the most two important paradigms used. In this paper we propose a new algorithm for recognition of handwritten t...

  15. Video Game Characters. Theory and Analysis

    OpenAIRE

    Felix Schröter; Jan-Noël Thon

    2014-01-01

    This essay develops a method for the analysis of video game characters based on a theoretical understanding of their medium-specific representation and the mental processes involved in their intersubjective construction by video game players. We propose to distinguish, first, between narration, simulation, and communication as three modes of representation particularly salient for contemporary video games and the characters they represent, second, between narrative, ludic, and social experien...

  16. Charge-Shift Corrected Electronegativities and the Effect of Bond Polarity and Substituents on Covalent-Ionic Resonance Energy.

    Science.gov (United States)

    James, Andrew M; Laconsay, Croix J; Galbraith, John Morrison

    2017-07-13

    Bond dissociation energies and resonance energies for H n A-BH m molecules (A, B = H, C, N, O, F, Cl, Li, and Na) have been determined in order to re-evaluate the concept of electronegativity in the context of modern valence bond theory. Following Pauling's original scheme and using the rigorous definition of the covalent-ionic resonance energy provided by the breathing orbital valence bond method, we have derived a charge-shift corrected electronegativity scale for H, C, N, O, F, Cl, Li, and Na. Atomic charge shift character is defined using a similar approach resulting in values of 0.42, 1.06, 1.43, 1.62, 1.64, 1.44, 0.46, and 0.34 for H, C, N, O, F, Cl, Li, and Na, respectively. The charge-shift corrected electronegativity values presented herein follow the same general trends as Pauling's original values with the exception of Li having a smaller value than Na (1.57 and 1.91 for Li and Na respectively). The resonance energy is then broken down into components derived from the atomic charge shift character and polarization effects. It is then shown that most of the resonance energy in the charge-shift bonds H-F, H 3 C-F, and Li-CH 3 and borderline charge-shift H-OH is associated with polarity rather than the intrinsic atomic charge-shift character of the bonding species. This suggests a rebranding of these bonds as "polar charge-shift" rather than simply "charge-shift". Lastly, using a similar breakdown method, it is shown that the small effect the substituents -CH 3 , -NH 2 , -OH, and -F have on the resonance energy (<10%) is mostly due to changes in the charge-shift character of the bonding atom.

  17. The character of free topological groups II

    Directory of Open Access Journals (Sweden)

    Peter Nickolas

    2005-04-01

    Full Text Available A systematic analysis is made of the character of the free and free abelian topological groups on metrizable spaces and compact spaces, and on certain other closely related spaces. In the first case, it is shown that the characters of the free and the free abelian topological groups on X are both equal to the “small cardinal” d if X is compact and metrizable, but also, more generally, if X is a non-discrete k!-space all of whose compact subsets are metrizable, or if X is a non-discrete Polish space. An example is given of a zero-dimensional separable metric space for which both characters are equal to the cardinal of the continuum. In the case of a compact space X, an explicit formula is derived for the character of the free topological group on X involving no cardinal invariant of X other than its weight; in particular the character is fully determined by the weight in the compact case. This paper is a sequel to a paper by the same authors in which the characters of the free groups were analysed under less restrictive topological assumptions.

  18. Covalent structure of the insect toxin of the North African scorpion Androctonus australis Hector

    International Nuclear Information System (INIS)

    Darbon, H.; Kopeyan, C.; Rietschoten, J. van; Rochat, H.; Zlotkin, E.

    1982-01-01

    The complete covalent structure of the insect toxin purified from the venom of the North-African scorpion Androctonus australis Hector was described. Its amino acid sequence was established by phenylisothiocyanate degradation of several protein derivatives and proteolytic fragments in a liquid protein sequencer using either a ''protein'' or a ''peptide'' program. The position of the four disulfide bridges were deduced by analysis of proteolytic peptides before and after performic oxidation, and by partial labeling of the half cystine residues with [ 14 C]-iodoacetic acid and determining the specific radioactivities of the S-[ 14 C]-carboxymethylated phenylthiohydantoin cysteines. The sequences of the insect and mammal toxins from scorpions can be aligned with homology with the positions of seven half-cystine residues as registers. The mammal and insect toxins have three disulfide bridges at homologous positions. The fourth bridge is different in that Cys 12 in mammal toxin II is replaced by Cys 38 in the insect toxin. It is likely that the position of the disulfide bridges is the same for all scorpion neurotoxins active on mammals. We believe that the shift of one half-cystine residue in the insect toxin may induce a conformational change in the structure of the protein, which, in turn, may partially account for the total specificity of this toxin for insect nervous system. (author)

  19. Leading Character?s Antisocial Personality Disorder In James B Stewart?s Blind Eye

    OpenAIRE

    Lestari, Ayu

    2016-01-01

    110705043 The title of this thesis isLeading Character?s Antisocial Personality Disorder in James B Stewart?s Blind Eyethat is research about antisocial personality of leading character in the novel, namely Dr. Michael Swango. The purpose of this thesis is to find out characteristic of Swango that show he has antisocial personality disorder and to know the causes of his disorder. The writer refers to theory antisocial personality disorder that take in a research of APA (American Psychiatri...

  20. Character Play – The use of game characters in multi- player Role Playing Games across platforms

    DEFF Research Database (Denmark)

    Tychsen, Anders; Hitchens, M.; Brolund, T.

    2008-01-01

    histories of game characters. This article presents results from a comprehensive empirical study of the way complex game characters are utilized by players in multiplayer role-playing games across two different media platforms. The results indicate that adult players are capable of comprehending...... and utilizing game characters with well-defined personalities and backgrounds, as well as rules-based components. Furthermore, that the game format plays a significant role in the pattern of usage of the character elements. This pattern appears directly linked with variations in the way that the different game...

  1. Seed characters and their usefulness in the separation of Asteraceae species

    Directory of Open Access Journals (Sweden)

    Michelli Fernandes Batista

    2015-10-01

    Full Text Available Studies on seed structure of Asteraceae have received little attention of botanists. Seed structure in Asteraceae is analyzed to evaluate the usefulness of characters in the separation of species through the analysis of nine weedy species. Seeds originate from anatropous, unitegmic and tenuinucellate ovules. The partial collapse of the developing seed coat is a common characteristic in the Asteraceae species studied. The testa consists of crushed and thin-walled cells in almost all of the species studied herein, except for Elephantopus mollis and Parthenium hysterophorus, which showed exotesta cells with U-shaped thickening. The analysis revealed high uniformity in seed characters.

  2. IMAGE PROCESSING BASED OPTICAL CHARACTER RECOGNITION USING MATLAB

    OpenAIRE

    Jyoti Dalal*1 & Sumiran Daiya2

    2018-01-01

    Character recognition techniques associate a symbolic identity with the image of character. In a typical OCR systems input characters are digitized by an optical scanner. Each character is then located and segmented, and the resulting character image is fed into a pre-processor for noise reduction and normalization. Certain characteristics are the extracted from the character for classification. The feature extraction is critical and many different techniques exist, each having its strengths ...

  3. A Classification Scheme for Literary Characters

    Directory of Open Access Journals (Sweden)

    Matthew Berry

    2017-10-01

    Full Text Available There is no established classification scheme for literary characters in narrative theory short of generic categories like protagonist vs. antagonist or round vs. flat. This is so despite the ubiquity of stock characters that recur across media, cultures, and historical time periods. We present here a proposal of a systematic psychological scheme for classifying characters from the literary and dramatic fields based on a modification of the Thomas-Kilmann (TK Conflict Mode Instrument used in applied studies of personality. The TK scheme classifies personality along the two orthogonal dimensions of assertiveness and cooperativeness. To examine the validity of a modified version of this scheme, we had 142 participants provide personality ratings for 40 characters using two of the Big Five personality traits as well as assertiveness and cooperativeness from the TK scheme. The results showed that assertiveness and cooperativeness were orthogonal dimensions, thereby supporting the validity of using a modified version of TK’s two-dimensional scheme for classifying characters.

  4. Benchmark for license plate character segmentation

    Science.gov (United States)

    Gonçalves, Gabriel Resende; da Silva, Sirlene Pio Gomes; Menotti, David; Shwartz, William Robson

    2016-09-01

    Automatic license plate recognition (ALPR) has been the focus of many researches in the past years. In general, ALPR is divided into the following problems: detection of on-track vehicles, license plate detection, segmentation of license plate characters, and optical character recognition (OCR). Even though commercial solutions are available for controlled acquisition conditions, e.g., the entrance of a parking lot, ALPR is still an open problem when dealing with data acquired from uncontrolled environments, such as roads and highways when relying only on imaging sensors. Due to the multiple orientations and scales of the license plates captured by the camera, a very challenging task of the ALPR is the license plate character segmentation (LPCS) step, because its effectiveness is required to be (near) optimal to achieve a high recognition rate by the OCR. To tackle the LPCS problem, this work proposes a benchmark composed of a dataset designed to focus specifically on the character segmentation step of the ALPR within an evaluation protocol. Furthermore, we propose the Jaccard-centroid coefficient, an evaluation measure more suitable than the Jaccard coefficient regarding the location of the bounding box within the ground-truth annotation. The dataset is composed of 2000 Brazilian license plates consisting of 14000 alphanumeric symbols and their corresponding bounding box annotations. We also present a straightforward approach to perform LPCS efficiently. Finally, we provide an experimental evaluation for the dataset based on five LPCS approaches and demonstrate the importance of character segmentation for achieving an accurate OCR.

  5. Combining ability of elephant grass based on nutritional characters

    Directory of Open Access Journals (Sweden)

    Vanessa Quitete Ribeiro da Silva

    2014-03-01

    Full Text Available The objective of the work was to evaluate the effects of general combining ability (CGC of the parents and specific combining ability (CEC in the elephant grass hybrids by diallel analysis adapted to partial diallel crosses based on nutritional characters. Sixteen hybrids and eight parents in a randomized block design with three replications were evaluated. The study considered percentage of dry matter (%DM, ash (%ASH, crude protein (%CP and neutral detergent fiber (NDF. There were significant differences among genotypes for the traits evaluated, with a predominance of dominance gene effect. Based on CGC, the best parents were Taiwan A-144, Vruckwona Africana e Taiwan A-146. The best intersections based on CEC were Taiwan A-144 x Taiwan A-146, Vruckwona Africana x Taiwan A-146, Vruckwona Africana x Mercker S.E.A., Vruckwona Africana x Napier nº2 e Pusa Napier nº2 x Mercker Santa Rita.

  6. Covalent DNA-protein crosslinking occurs after hyperthermia and radiation

    International Nuclear Information System (INIS)

    Cress, A.E.; Bowden, G.T.

    1983-01-01

    Covalent DNA-protein crosslinks occur in exponentially growing mouse leukemia cells (L1210) after exposure to ionizing radiation. The amount of DNA-protein crosslinks as measured by a filter binding assay is dose dependent upon X irradiation. Although hyperthermia and radiation in combination are synergistic with respect to cell lethality, the combination does not result in an increase of DNA-protein crosslinks when assayed immediately following treatments. Hyperthermia (43 degrees C/15 min) given prior to radiation does not alter the radiation dose dependency of the amount of initial crosslinking. In addition, the amount of DNA-protein crosslinking produced by heat plus radiation is independent of the length of heating the cells at 43 degrees C. The DNA-protein crosslinks produced by 50-Gy X ray alone are removed after 2 hr at 37 degrees C. However, if hyperthermia (43 degrees C/15 min) is given prior to 100-Gy X ray, the removal of DNA-protein crosslinks is delayed until 4.0 hr after radiation. Phospho-serine and phospho-threonine bonds are not produced with either radiation or the combination of hyperthermia plus radiation as judged by the resistance of the bonds to guanidine hydrochloride. However, hyperthermia plus radiation causes an increase in phosphate to nitrogen type bonding. These results show that radiation alone causes covalent DNA-protein crosslinks. Hyperthermia in combination with radiation does not increase the total amount of the crosslinks but delays the removal of the crosslinks and alters the distribution of the types of chemical bonding. These data suggest that the synergistic action on hyperthermia with radiation is more related to the rate of removal and the type of chemical bonding involved in the covalent DNA-protein crosslinks rather than the amount of DNA-protein crosslinks

  7. Macromolecular weight specificity in covalent binding of bromobenzene

    International Nuclear Information System (INIS)

    Sun, J.D.; Dent, J.G.

    1984-01-01

    Bromobenzene is a hepatotoxicant that causes centrilobular necrosis. Pretreatment of animals with 3-methylcholanthrene decreases and phenobarbital pretreatment enhances the hepatotoxic action of this compound. We have investigated the macromolecular weight specificity of the covalent interactions of bromobenzene with liver macromolecules following incubation of [ 14 C]bromobenzene in isolated hepatocytes. Hepatocytes were prepared from Fischer-344 rats treated for 3 days with 3-methylcholanthrene, phenobarbital, or normal saline. After a 1-hr incubation, total covalent binding, as measured by sodium dodecyl sulfate-equilibrium dialysis, was twofold less in hepatocytes from 3-methylcholanthrene-treated rats and sixfold greater in hepatocytes from phenobarbital-treated rats, as compared to hepatocytes from control animals. Analysis of the arylated macromolecules by electrophoresis on 15% sodium dodecyl sulfate-polyacrylamide disc gels indicated that in the first 1 to 3 min of incubation substantial amounts of covalently bound radiolabel were associated with macromolecules of between 20,000 and 40,000. The amount of radioactivity associated with these macromolecules rapidly diminished in hepatocytes from control and 3-methylcholanthrene-treated animals. In hepatocytes from phenobarbital-treated animals, the amount of radioactivity associated with macromolecules, 20,000, increased throughout the incubation. The amount of radiolabel associated with macromolecules, 20,000, increased in all incubations. When nontoxic doses of phenylmethylsulfonyl fluoride, a specific inhibitor of serine proteases, were added to control hepatocytes incubated with [ 14 C]-bromobenzene, the decrease in radioactivity associated with larger (greater than 20,000) macromolecules was inhibited and a corresponding lack of increase in radioactivity associated with smaller macromolecules was observed

  8. The Inaccuracy of National Character Stereotypes

    Science.gov (United States)

    McCrae, Robert R.; Chan, Wayne; Jussim, Lee; De Fruyt, Filip; Löckenhoff, Corinna E.; De Bolle, Marleen; Costa, Paul T.; Hřebíčková, Martina; Graf, Sylvie; Realo, Anu; Allik, Jüri; Nakazato, Katsuharu; Shimonaka, Yoshiko; Yik, Michelle; Ficková, Emília; Brunner-Sciarra, Marina; Reátigui, Norma; de Figueora, Nora Leibovich; Schmidt, Vanina; Ahn, Chang-kyu; Ahn, Hyun-nie; Aguilar-Vafaie, Maria E.; Siuta, Jerzy; Szmigielska, Barbara; Cain, Thomas R.; Crawford, Jarret T.; Mastor, Khairul Anwar; Rolland, Jean-Pierre; Nansubuga, Florence; Miramontez, Daniel R.; Benet-Martínez, Veronica; Rossier, Jérôme; Bratko, Denis; Marušić, Iris; Halberstadt, Jamin; Yamaguchi, Mami; Knežević, Goran; Purić, Danka; Martin, Thomas A.; Gheorghiu, Mirona; Smith, Peter B.; Barbaranelli, Claudio; Wang, Lei; Shakespeare-Finch, Jane; Lima, Margarida P.; Klinkosz, Waldemar; Sekowski, Andrzej; Alcalay, Lidia; Simonetti, Franco; Avdeyeva, Tatyana V.; Pramila, V. S.; Terracciano, Antonio

    2013-01-01

    Consensual stereotypes of some groups are relatively accurate, whereas others are not. Previous work suggesting that national character stereotypes are inaccurate has been criticized on several grounds. In this article we (a) provide arguments for the validity of assessed national mean trait levels as criteria for evaluating stereotype accuracy; and (b) report new data on national character in 26 cultures from descriptions (N=3,323) of the typical male or female adolescent, adult, or old person in each. The average ratings were internally consistent and converged with independent stereotypes of the typical culture member, but were weakly related to objective assessments of personality. We argue that this conclusion is consistent with the broader literature on the inaccuracy of national character stereotypes. PMID:24187394

  9. Transliterating non-ASCII characters with Python

    Directory of Open Access Journals (Sweden)

    Seth Bernstein

    2013-10-01

    Full Text Available This lesson shows how to use Python to transliterate automatically a list of words from a language with a non-Latin alphabet to a standardized format using the American Standard Code for Information Interchange (ASCII characters. It builds on readers’ understanding of Python from the lessons “Viewing HTML Files,” “Working with Web Pages,” “From HTML to List of Words (part 1” and “Intro to Beautiful Soup.” At the end of the lesson, we will use the transliteration dictionary to convert the names from a database of the Russian organization Memorial from Cyrillic into Latin characters. Although the example uses Cyrillic characters, the technique can be reproduced with other alphabets using Unicode.

  10. APLIKASI SPOKES-CHARACTERS DALAM KAITAN DENGAN MEREK PRODUK

    Directory of Open Access Journals (Sweden)

    Caroline Widjoyo

    2004-01-01

    Full Text Available Advertisement by using spokes-characters have potency to alter the choice of consumer brand with the compared to bigger impact which do not use the spokes-character. A lot of producer which hence spokes-character to increase assess to sell from a product. Spokes-Characters experience of the evolution from time to time keep abreast of the era%2C now emerge the new type of spokes-character and its application. Abstract in Bahasa Indonesia : Iklan dengan spokes-characters berpotensi mengubah pilihan merek konsumen dengan dampak lebih besar dibanding yang tidak menggunakan spokes-character. Banyak produsen yang memakai spokes-character untuk meningkatkan nilai jual dari sebuah produk. Spokes-characters mengalami evolusi dari masa ke masa mengikuti perkembangan jaman%2C sekarang muncul jenis baru spokes-character dan aplikasinya. spokes-characters%2C advertising%2C branding.

  11. Effect of photocurrent enhancement in porphyrin–graphene covalent hybrids

    International Nuclear Information System (INIS)

    Tang, Jianguo; Niu, Lin; Liu, Jixian; Wang, Yao; Huang, Zhen; Xie, Shiqiang; Huang, Linjun; Xu, Qingsong; Wang, Yuan; Belfiore, Laurence A.

    2014-01-01

    Graphene oxide (GO) sheets were covalently functionalized with 5-p-aminophenyl-10,15,20-triphenylporphyrin (NH 2 TPP) by an amidation reaction between the amino group in NH 2 TPP and carboxyl groups in GO. The Fourier transform infrared spectroscopy, nuclear magnetic resonance, scanning and transmission electron microscopies reveal that NH 2 TPP covalent bonds form on the double surface of graphene oxide sheets, generating a unique nano-framework, i.e., NH 2 TPP-graphene-NH 2 TPP. Its UV–visible spectroscopy reveals that the absorption spectrum is not a linear superposition of the spectra of NH 2 TPP and graphene oxide, because a 59 nm red shift of the strong graphene oxide absorption is observed from 238 to 297 nm, with significant spectral broadening between 300 and 700 nm. Fluorescence emission spectroscopy indicates efficient quenching of NH 2 TPP photoluminescence in this hybrid material, suggesting that photo-induced electron transfer occurs at the interface between NH 2 TPP and GO. A reversible on/off photo-current density of 47 mA/cm 2 is observed when NH 2 TPP-graphene-NH 2 TPP hybrid sandwiches are subjected to pulsed white-light illumination. Covalently-bound porphyrins decrease the optical HOMO/LUMO band gap of graphene oxide by ≈ 1 eV, according to UV–visible spectroscopy. Cyclic voltammetry predicts a small HOMO/LUMO band gap of 0.84 eV for NH 2 TPP-graphene-NH 2 TPP hybrid sandwiches, which is consistent with efficient electron transfer and fluorescence quenching. - Highlights: • Porphyrins are covalently bound to sheets of graphene oxide via an amidation reaction. • The formed hetero-junction interface decreases the optical band gap of graphene oxide. • Cyclic voltammetry predicts a graphene oxide band gap of 0.84 eV, which is easily photo-excited. • Its on/off photo-current density of 46 μA/cm 2 is 5-fold larger than that for physically stacked hybrid

  12. The Search for Covalently Ligandable Proteins in Biological Systems

    Directory of Open Access Journals (Sweden)

    Syed Lal Badshah

    2016-09-01

    Full Text Available This commentary highlights the recent article published in Nature, June 2016, titled: “Proteome-wide covalent ligand discovery in native biological systems”. They screened the whole proteome of different human cell lines and cell lysates. Around 700 druggable cysteines in the whole proteome were found to bind the electrophilic fragments in both active and inactive states of the proteins. Their experiment and computational docking results agreed with one another. The usefulness of this study in terms of bringing a change in medicinal chemistry is highlighted here.

  13. Covalent functionalization of carbon nanotubes with tetramanganese complexes

    International Nuclear Information System (INIS)

    Meyer, Carola; Frielinghaus, Robert; Saelhoff, Anna-Katharina; Schneider, Claus M.; Besson, Claire; Floetotto, Henrik; Koegerler, Paul; Houben, Lothar

    2012-01-01

    We present first results on the covalent chemical functionalization of single-walled carbon nanotubes with polynuclear {Mn 4 } coordination complexes. Raman spectra prove that the reaction can only be achieved for tubes which have been oxidized to create carboxylic groups. HRTEM is used to show that the reaction can be carried out directly on a substrate as well. Analysis of the D/G intensity ratio for different oxidation times shows that it is possible to reduce the amount of defects created. This is important for the future application of this material in transport devices. (Copyright copyright 2012 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  14. Reaction mechanisms for on-surface synthesis of covalent nanostructures

    International Nuclear Information System (INIS)

    Björk, J

    2016-01-01

    In recent years, on-surface synthesis has become an increasingly popular strategy to form covalent nanostructures. The approach has great prospects for facilitating the manufacture of a range of fascinating materials with atomic precision. However, the on-surface reactions are enigmatic to control, currently restricting its bright perspectives and there is a great need to explore how the reactions are governed. The objective of this topical review is to summarize theoretical work that has focused on comprehending on-surface synthesis protocols through studies of reaction mechanisms. (topical review)

  15. Character Issues: Reality Character Problems and Solutions through Education in Indonesia

    Science.gov (United States)

    Saidek, Abdul Rahim; Islami, Raisul; Abdoludin

    2016-01-01

    Weak character education raises the problem of corruption, a fight between students, free sex, drugs and rape/abortion indicate that the issue of character education of the nation must be improved and the concern of all parties, the nation's leaders, law enforcement officers, educators, religious leaders, groups and other etc. There are two…

  16. Character Education in Print: Content Analysis of Character Education in Introduction to Education Textbooks

    Science.gov (United States)

    Protz, Babette Marisa

    2013-01-01

    Albert Einstein is credited with saying that the most important component of education is the development of students' character. While debate exists as to the delivery of character education in the public schools, it must be recognized that not all students have a support system outside of the schoolhouse. Consequently, when character…

  17. Partial tooth gear bearings

    Science.gov (United States)

    Vranish, John M. (Inventor)

    2010-01-01

    A partial gear bearing including an upper half, comprising peak partial teeth, and a lower, or bottom, half, comprising valley partial teeth. The upper half also has an integrated roller section between each of the peak partial teeth with a radius equal to the gear pitch radius of the radially outwardly extending peak partial teeth. Conversely, the lower half has an integrated roller section between each of the valley half teeth with a radius also equal to the gear pitch radius of the peak partial teeth. The valley partial teeth extend radially inwardly from its roller section. The peak and valley partial teeth are exactly out of phase with each other, as are the roller sections of the upper and lower halves. Essentially, the end roller bearing of the typical gear bearing has been integrated into the normal gear tooth pattern.

  18. Refined geometric transition and qq-characters

    Science.gov (United States)

    Kimura, Taro; Mori, Hironori; Sugimoto, Yuji

    2018-01-01

    We show the refinement of the prescription for the geometric transition in the refined topological string theory and, as its application, discuss a possibility to describe qq-characters from the string theory point of view. Though the suggested way to operate the refined geometric transition has passed through several checks, it is additionally found in this paper that the presence of the preferred direction brings a nontrivial effect. We provide the modified formula involving this point. We then apply our prescription of the refined geometric transition to proposing the stringy description of doubly quantized Seiberg-Witten curves called qq-characters in certain cases.

  19. Essays on partial retirement

    NARCIS (Netherlands)

    Kantarci, T.

    2012-01-01

    The five essays in this dissertation address a range of topics in the micro-economic literature on partial retirement. The focus is on the labor market behavior of older age groups. The essays examine the economic and non-economic determinants of partial retirement behavior, the effect of partial

  20. Character Apps for Children's Snacks: Effects of Character Awareness on Snack Selection and Consumption Patterns.

    Science.gov (United States)

    Putnam, Marisa M; Cotto, Caroline E; Calvert, Sandra L

    2018-04-01

    Media characters are used to market snacks that are typically of poor nutritional value, which has been linked to childhood obesity. This study examines whether children's snack selections and consumption patterns are influenced by an app depicting a popular children's media character, as well as the role that children's awareness of the character plays. The results can increase our understanding of how to encourage healthier snack selection and consumption in newer game-based marketing venues, such as apps. Four- and 5-year-old children (N = 132) played a bowling game on an iPad with no character or with a character holding either healthier or unhealthy snacks. After app-play, children selected and consumed healthier or unhealthy snacks. Children's awareness of the character was measured by children's verbalizations of the character's name during or after app-play. An ordered logistic regression found no significant effect of treatment conditions compared with the control group. Within treatment conditions, awareness of the character led to selection and consumption of more healthy snacks in the healthier condition (odds ratio β = 10.340, P = 0.008), and of unhealthy snacks in the unhealthy condition (odds ratio β = 0.228, P = 0.033), but children were unaware that the character influenced their decisions. Results suggest that young children will choose and consume healthier, not just unhealthy, products when they are aware that a popular character in an app is associated with the snack, potentially leading to healthier eating patterns.

  1. Covalent Organic Frameworks: From Materials Design to Biomedical Application

    Directory of Open Access Journals (Sweden)

    Fuli Zhao

    2017-12-01

    Full Text Available Covalent organic frameworks (COFs are newly emerged crystalline porous polymers with well-defined skeletons and nanopores mainly consisted of light-weight elements (H, B, C, N and O linked by dynamic covalent bonds. Compared with conventional materials, COFs possess some unique and attractive features, such as large surface area, pre-designable pore geometry, excellent crystallinity, inherent adaptability and high flexibility in structural and functional design, thus exhibiting great potential for various applications. Especially, their large surface area and tunable porosity and π conjugation with unique photoelectric properties will enable COFs to serve as a promising platform for drug delivery, bioimaging, biosensing and theranostic applications. In this review, we trace the evolution of COFs in terms of linkages and highlight the important issues on synthetic method, structural design, morphological control and functionalization. And then we summarize the recent advances of COFs in the biomedical and pharmaceutical sectors and conclude with a discussion of the challenges and opportunities of COFs for biomedical purposes. Although currently still at its infancy stage, COFs as an innovative source have paved a new way to meet future challenges in human healthcare and disease theranostic.

  2. From covalent bonding to coalescence of metallic nanorods

    Directory of Open Access Journals (Sweden)

    Lee Soohwan

    2011-01-01

    Full Text Available Abstract Growth of metallic nanorods by physical vapor deposition is a common practice, and the origin of their dimensions is a characteristic length scale that depends on the three-dimensional Ehrlich-Schwoebel (3D ES barrier. For most metals, the 3D ES barrier is large so the characteristic length scale is on the order of 200 nm. Using density functional theory-based ab initio calculations, this paper reports that the 3D ES barrier of Al is small, making it infeasible to grow Al nanorods. By analyzing electron density distributions, this paper shows that the small barrier is the result of covalent bonding in Al. Beyond the infeasibility of growing Al nanorods by physical vapor deposition, the results of this paper suggest a new mechanism of controlling the 3D ES barrier and thereby nanorod growth. The modification of local degree of covalent bonding, for example, via the introduction of surfactants, can increase the 3D ES barrier and promote nanorod growth, or decrease the 3D ES barrier and promote thin film growth.

  3. Bifunctional avidin with covalently modifiable ligand binding site.

    Directory of Open Access Journals (Sweden)

    Jenni Leppiniemi

    Full Text Available The extensive use of avidin and streptavidin in life sciences originates from the extraordinary tight biotin-binding affinity of these tetrameric proteins. Numerous studies have been performed to modify the biotin-binding affinity of (streptavidin to improve the existing applications. Even so, (streptavidin greatly favours its natural ligand, biotin. Here we engineered the biotin-binding pocket of avidin with a single point mutation S16C and thus introduced a chemically active thiol group, which could be covalently coupled with thiol-reactive molecules. This approach was applied to the previously reported bivalent dual chain avidin by modifying one binding site while preserving the other one intact. Maleimide was then coupled to the modified binding site resulting in a decrease in biotin affinity. Furthermore, we showed that this thiol could be covalently coupled to other maleimide derivatives, for instance fluorescent labels, allowing intratetrameric FRET. The bifunctional avidins described here provide improved and novel tools for applications such as the biofunctionalization of surfaces.

  4. Privileged Electrophile Sensors: A Resource for Covalent Drug Development.

    Science.gov (United States)

    Long, Marcus John Curtis; Aye, Yimon

    2017-07-20

    This Perspective delineates how redox signaling affects the activity of specific enzyme isoforms and how this property may be harnessed for rational drug design. Covalent drugs have resurged in recent years and several reports have extolled the general virtues of developing irreversible inhibitors. Indeed, many modern pharmaceuticals contain electrophilic appendages. Several invoke a warhead that hijacks active-site nucleophiles whereas others take advantage of spectator nucleophilic side chains that do not participate in enzymatic chemistry, but are poised to bind/react with electrophiles. The latest data suggest that innate electrophile sensing-which enables rapid reaction with an endogenous signaling electrophile-is a quintessential resource for the development of covalent drugs. For instance, based on recent work documenting isoform-specific electrophile sensing, isozyme non-specific drugs may be converted to isozyme-specific analogs by hijacking privileged first-responder electrophile-sensing cysteines. Because this approach targets functionally relevant cysteines, we can simultaneously harness previously untapped moonlighting roles of enzymes linked to redox sensing. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. Solvent-free covalent functionalization of nanodiamond with amines

    International Nuclear Information System (INIS)

    Basiuk, Elena V.; Santamaría-Bonfil, Adriana; Meza-Laguna, Victor; Gromovoy, Taras Yu.; Alvares-Zauco, Edgar; Contreras-Torres, Flavio F.; Rizo, Juan; Zavala, Guadalupe; Basiuk, Vladimir A.

    2013-01-01

    Covalent functionalization of pristine nanodiamond (ND) with 1,12-diaminododecane (DAD), 1,5-diaminonaphthalene (DAN), poly(ethylene glycol) diamine (PEGDA), and polyethylenimine (PEI) was carried out by employing solvent-free methodology, which is based on thermal instead of chemical activation of carboxylic groups at ND surface. A simple solubility/dispersibility test in water and isopropanol showed an increased lipophilicity of the functionalized samples. The conversion of intrinsic carboxylic groups into the corresponding amide derivatives was characterized by means of Fourier-transform infrared spectroscopy. Thermogravimetric analysis found the highest organic content of about 18% for ND-PEI, followed by ND-DAD, for which the contribution of covalently bonded diamine was estimated to be of ca. 10%. In temperature programmed desorption measurements with mass spectrometric detection, the presence of organic functionalizing groups changed both mass spectra and thermodesorption curves of ND. The changes in morphology of primary and secondary ND aggregates were characterized by scanning and transmission electron microscopy, as well as by atomic force microscopy. The current–voltage measurements under atmospheric pressure found an increased conductivity for ND-DAN, as compared to that of pristine ND, whereas for ND-DAD, ND-PEGDA and ND-PEI a dramatic decrease in conductivity due to functionalization was observed.

  6. Solvent-free covalent functionalization of nanodiamond with amines

    Energy Technology Data Exchange (ETDEWEB)

    Basiuk, Elena V., E-mail: elenagd@unam.mx [Centro de Ciencias Aplicadas y Desarrollo Tecnológico, Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, 04510 México D.F. (Mexico); Santamaría-Bonfil, Adriana; Meza-Laguna, Victor [Centro de Ciencias Aplicadas y Desarrollo Tecnológico, Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, 04510 México D.F. (Mexico); Gromovoy, Taras Yu. [Institute of Surface Chemistry, National Academy of Sciences of the Ukraine, Gen. Naumova 17, 03164 Kiev (Ukraine); Alvares-Zauco, Edgar [Facultad de Ciencias, Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, 04510 México D.F. (Mexico); Contreras-Torres, Flavio F.; Rizo, Juan [Centro de Ciencias Aplicadas y Desarrollo Tecnológico, Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, 04510 México D.F. (Mexico); Zavala, Guadalupe [Instituto de Biotecnología, Universidad Nacional Autónoma de México, Av. Universidad 2001, Col. Chamilpa, 62210, Cuernavaca, Morelos (Mexico); Basiuk, Vladimir A. [Instituto de Ciencias Nucleares, Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, 04510 México, D.F. (Mexico)

    2013-06-15

    Covalent functionalization of pristine nanodiamond (ND) with 1,12-diaminododecane (DAD), 1,5-diaminonaphthalene (DAN), poly(ethylene glycol) diamine (PEGDA), and polyethylenimine (PEI) was carried out by employing solvent-free methodology, which is based on thermal instead of chemical activation of carboxylic groups at ND surface. A simple solubility/dispersibility test in water and isopropanol showed an increased lipophilicity of the functionalized samples. The conversion of intrinsic carboxylic groups into the corresponding amide derivatives was characterized by means of Fourier-transform infrared spectroscopy. Thermogravimetric analysis found the highest organic content of about 18% for ND-PEI, followed by ND-DAD, for which the contribution of covalently bonded diamine was estimated to be of ca. 10%. In temperature programmed desorption measurements with mass spectrometric detection, the presence of organic functionalizing groups changed both mass spectra and thermodesorption curves of ND. The changes in morphology of primary and secondary ND aggregates were characterized by scanning and transmission electron microscopy, as well as by atomic force microscopy. The current–voltage measurements under atmospheric pressure found an increased conductivity for ND-DAN, as compared to that of pristine ND, whereas for ND-DAD, ND-PEGDA and ND-PEI a dramatic decrease in conductivity due to functionalization was observed.

  7. Technical guide for monitoring selected conditions related to wilderness character

    Science.gov (United States)

    Peter Landres; Steve Boutcher; Liese Dean; Troy Hall; Tamara Blett; Terry Carlson; Ann Mebane; Carol Hardy; Susan Rinehart; Linda Merigliano; David N. Cole; Andy Leach; Pam Wright; Deb Bumpus

    2009-01-01

    The purpose of monitoring wilderness character is to improve wilderness stewardship by providing managers a tool to assess how selected actions and conditions related to wilderness character are changing over time. Wilderness character monitoring provides information to help answer two key questions about wilderness character and wilderness stewardship: 1. How is...

  8. Guideline for Optical Character Recognition Forms.

    Science.gov (United States)

    National Bureau of Standards (DOC), Washington, DC.

    This publication provides materials relating to the design, preparation, acquisition, inspection, and application of Optical Character Recognition (OCR) forms in data entry systems. Since the materials are advisory and tutorial in nature, this publication has been issued as a guideline rather than as a standard in the Federal Information…

  9. A New Experiment on Bengali Character Recognition

    Science.gov (United States)

    Barman, Sumana; Bhattacharyya, Debnath; Jeon, Seung-Whan; Kim, Tai-Hoon; Kim, Haeng-Kon

    This paper presents a method to use View based approach in Bangla Optical Character Recognition (OCR) system providing reduced data set to the ANN classification engine rather than the traditional OCR methods. It describes how Bangla characters are processed, trained and then recognized with the use of a Backpropagation Artificial neural network. This is the first published account of using a segmentation-free optical character recognition system for Bangla using a view based approach. The methodology presented here assumes that the OCR pre-processor has presented the input images to the classification engine described here. The size and the font face used to render the characters are also significant in both training and classification. The images are first converted into greyscale and then to binary images; these images are then scaled to a fit a pre-determined area with a fixed but significant number of pixels. The feature vectors are then formed extracting the characteristics points, which in this case is simply a series of 0s and 1s of fixed length. Finally, an artificial neural network is chosen for the training and classification process.

  10. Movement and Character. Lecture, London, 1946

    Science.gov (United States)

    Montesorri, Maria

    2013-01-01

    Dr. Montessori's words from the 1946 London Lectures describe principles of intelligence and character, the work of the hand, and movement with a purpose as being integral to self-construction. The perfection of movement is spiritual, says Dr. Montessori. Repetition of practical life exercises are exercises in movement with the dignity of human…

  11. Computational Design of Animated Mechanical Characters

    Science.gov (United States)

    Coros, Stelian; Thomaszewski, Bernhard; DRZ Team Team

    2014-03-01

    A factor key to the appeal of modern CG movies and video-games is that the virtual worlds they portray place no bounds on what can be imagined. Rapid manufacturing devices hold the promise of bringing this type of freedom to our own world, by enabling the fabrication of physical objects whose appearance, deformation behaviors and motions can be precisely specified. In order to unleash the full potential of this technology however, computational design methods that create digital content suitable for fabrication need to be developed. In recent work, we presented a computational design system that allows casual users to create animated mechanical characters. Given an articulated character as input, the user designs the animated character by sketching motion curves indicating how they should move. For each motion curve, our framework creates an optimized mechanism that reproduces it as closely as possible. The resulting mechanisms are attached to the character and then connected to each other using gear trains, which are created in a semi-automated fashion. The mechanical assemblies generated with our system can be driven with a single input driver, such as a hand-operated crank or an electric motor, and they can be fabricated using rapid prototyping devices.

  12. Reflecting on Character (Reflexionando Sobre el Caracter).

    Science.gov (United States)

    Candelaria, Cordelia

    1980-01-01

    Responding to the "Proyecto Resolana" article in the July/August 1980 issue of this journal, the article notes the heterogeneity of Hispanic Americans, the three main effects of the European conquest on people of the Western Hemisphere, and attempts to further define the character of Hispanic Americans. (SB)

  13. Theological Education and Character Formation in Nigerian ...

    African Journals Online (AJOL)

    This paper presents theological education and character formation in Nigerian Christianity. Some theologians and religious scholars do not offer any practical recipes in dealing with the major pressing problems of theological training for Christian ministry today in the 21st century Nigerian society. Some priests, lay workers ...

  14. Emotional characters for automatic plot creation

    NARCIS (Netherlands)

    Theune, Mariet; Rensen, S.; op den Akker, Hendrikus J.A.; Heylen, Dirk K.J.; Nijholt, Antinus; Göbel, S.; Spierling, U.; Hoffmann, A.; Iurgel, I.; Schneider, O.; Dechau, J.; Feix, A.

    The Virtual Storyteller is a multi-agent framework for automatic story generation. In this paper we describe how plots emerge from the actions of semi-autonomous character agents, focusing on the influence of the characters’ emotions on plot development.

  15. Moral-Character Development for Teacher Education

    Science.gov (United States)

    Lapsley, Daniel; Woodbury, Ryan

    2016-01-01

    In this article the authors accept the common view that moral-character education is immanent to the life of classroom and schools and inevitable even when remanded to the hidden curriculum. Most schools claim to address the moral formation of students, and many educators enter the profession for values-laden reasons. Yet the language of values,…

  16. On Repairing Generated Behaviors for Graphical Characters

    DEFF Research Database (Denmark)

    Corradini, Andrea; Mehta, Manish

    2016-01-01

    In this paper, we continue our work on the creation of artificial intelligence (AI) behaviors for graphical interactive characters by novice users. We refer to novice users as any persons who do not have any particular skills, training and experience in both programming and design. The focus...

  17. Character Education: A Relationship with Building Health

    Science.gov (United States)

    Crider, Robert B.

    2012-01-01

    The purpose of the study is to investigate the relationship between the use of character education programming and school health. Measuring and improving school health is a process that supports social, emotional, ethical and civic education. Hoy, Tarter, and Kottkamp define this concept as a healthy school is one in which the institutional,…

  18. Morphological Characters and Histology of Pheretima darnleiensis

    Directory of Open Access Journals (Sweden)

    ANDY DARMAWAN

    2012-03-01

    Full Text Available Pheretima darnleiensis is a native earthworm of Southeast Asia, India, and Japan. Although it is commonly found in Indonesia, the earthworm has never been studied well. This study was aimed to examine the morphological characters and structure of its several organs for an identification purpose, which is important for the earthworm culture. Earthworms were collected in a plot of 55-150 × 55-150 cm width and 20 cm depth at Bogor Agricultural University in Darmaga and Baranangsiang Campuses by hand sorting method. Examinations were carried out on its external as well as internal characters. The histology of the organs was studied using paraffin method. The observed characters on P. darnleiensis were the presence of prostate gland, one pair of male pores on segment XVIII, a cylindrical body with perichaetine setae, caeca on segment XXVII, copulatory pouches without diverticula and stalked glands, bithecal spermatheca with nephridia, and the first spermathecal pore on segment 4/5. In addition, other characters found on P. darnleiensis were the presence of an annular clitellum on segment XIV-XVI, an epilobus prostomium with open base, approximately 40 single pointed setae on segment XIII, one midventral female pore on segment XIV, one pair of lateroventral male pores on segment XVIII, four pairs of lateroventral spermathecal pores on segment 4/5, 5/6, 6/7, 7/8, and the first middorsal dorsal pore on segment 12/13. The histology of P. darnleiensis showed basic structure as found in other earthworms.

  19. Computer Animation for Articulated 3D Characters

    NARCIS (Netherlands)

    Kiss, S.

    2002-01-01

    We present a review of the computer animation literature, mainly concentrating on articulated characters and at least some degree of interactivity or real time simulation. Advances in dierent techniques such as key-frame, motion capture (also known as mocap), dynamics, inverse kinematics (IK),

  20. Honesty, Cheating, and Character in College

    Science.gov (United States)

    Miller, Christian

    2013-01-01

    Most college faculty care about the characters of their students, especially when it comes to questions of honesty. But can students today be trusted not to cheat when completing papers and exams, and not to do so for the right reasons? In section one of this article, the author reviews some of the leading research on cheating behavior, and in…

  1. Interactive Character Deformation Using Simplified Elastic Models

    NARCIS (Netherlands)

    Luo, Z.

    2016-01-01

    This thesis describes the results of our research into realistic skin and model deformation methods aimed at the field of character deformation and animation. The main contributions lie in the properties of our deformation scheme. Our approach preserves the volume of the deformed object while

  2. DIAGNOSTIC CHARACTERS OF TOMOPTERNA AND RANA ...

    African Journals Online (AJOL)

    five-toed stage, of a spur on the hind foot, giving a six-toed appearance when the spur first appears. This feature ... In the main key, besides the spur on the foot, tail and spiracle characters were used, the former with the .... and is generally pale ... ' (p. 96) and 'They reach a maximum of 70 mm, and are flat, heavy tadpoles ..•.

  3. Amharic Character Generator | Gessesse | Zede Journal

    African Journals Online (AJOL)

    Zede Journal. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 7 (1986) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register. Amharic Character Generator. GA Gessesse. Abstract. No Abstract. Full Text:.

  4. [The aesthetic character of caring knowledge].

    Science.gov (United States)

    Tsai, Cheng-Yun

    2013-08-01

    The identity of nursing is founded on caring knowledge, which is derived from our understanding of its experience-revealed essence. This purposive knowledge differs from scientific knowledge because validity guides the latter and ethics guides the former. Therefore, justifying the objectivity of caring knowledge should be based on the aesthetic character of this knowledge rather than on a general social-science explanation.

  5. Building Character through Sports: Myth or Possibility?

    Science.gov (United States)

    Chandler, Timothy J. L.; Goldberg, Alan D.

    1990-01-01

    Asks whether striving to win in sports is compatible with belief participation in sports builds character. Identifies viewpoints on winning (winning as consequence and winning as experience). Suggests ways counselors might encourage athletes, coaches, and parents to perceive winning as experience so participation in sports can foster…

  6. Face of America Character Education Curriculum.

    Science.gov (United States)

    World T.E.A.M. Sports, Charlotte, NC.

    This document presents a description of the Face of America Classroom Program, a character education program based on a mission to bridge and build communities through sports. Three language arts lesson plans are provided on three themes: achievement, stereotypes (especially of people with disabilities), and strategies for healthy minds and…

  7. The Problem of Loyalty in Teaching Character

    Science.gov (United States)

    Stoll, Sharon K.

    2012-01-01

    In the last year, two prominent, famous, and revered coaches, Jim Tressel and Joe Paterno, committed disastrous lapses of ethics. Both coaches preached that sport and athletics build character. They either taught ethics or leadership courses at their institutions or were exemplars of ethical behavior in their personal and professional lives. Both…

  8. Cyberethics: Envisioning Character Education in Cyberspace

    Science.gov (United States)

    Whittier, David B.

    2013-01-01

    This article presents theory and research forming the framework of a graduate course in cyberethics education. The course content includes theory and research on the psychology of the Internet, moral development, and character education. Discussion includes application of these constructs to issues such as empathy, privacy, and other issues as…

  9. The inaccuracy of national character stereotypes

    Czech Academy of Sciences Publication Activity Database

    McCrae, R. R.; Chan, W.; Jussim, L.; De Fruyt, F.; Löckenhoff, C.E.; De Bolle, M.; Costa Jr., P.T.; Hřebíčková, Martina; Graf, Sylvie; Realo, A.; Allik, J.; Nakazato, K.; Shimonaka, Y.; Yik, M.; Ficková, E.; Brunner-Sciarra, M.; Reátigui, N.; Leibovich de Figueroa, N.; Schmidt, V.; Ahn, Ch.; Ahn, H.; Aguilar-Vafaie, M.E.; Siuta, J.; Szmigielska, B.; Cain, T.R.; Crawford, J.T.; Mastor, K.A.; Rolland, J. P.; Nansubuga, F.; Miramontez, D.R.; Benet-Martínez, V.; Rossier, J.; Bratko, D.; Marušić, I.; Halberstadt, J.; Yamaguchi, N.; Knežević, G.; Purić, D.; Martin, T. A.; Gheorghiu, M.; Smith, P.B.; Barbaranelli, C.; Wang, L.; Shakespeare-Finch, J.; Lima, M.P.; Klinkosz, W.; Sekowski, A.; Alcalay, L.; Simonetti, F.; Avdeyeva, T.V.; Pramila, V.S.; Terracciano, A.

    2013-01-01

    Roč. 47, č. 6 (2013), s. 831-842 ISSN 0092-6566 R&D Projects: GA ČR GA13-25656S Institutional support: RVO:68081740 Keywords : national character * stereotypes * Five-Factor Model of Personality Subject RIV: AN - Psychology Impact factor: 2.011, year: 2013

  10. Animal regeneration: ancestral character or evolutionary novelty?

    Science.gov (United States)

    Slack, Jonathan Mw

    2017-09-01

    An old question about regeneration is whether it is an ancestral character which is a general property of living matter, or whether it represents a set of specific adaptations to the different circumstances faced by different types of animal. In this review, some recent results on regeneration are assessed to see if they can throw any new light on this question. Evidence in favour of an ancestral character comes from the role of Wnt and bone morphogenetic protein signalling in controlling the pattern of whole-body regeneration in acoels, which are a basal group of bilaterian animals. On the other hand, there is some evidence for adaptive acquisition or maintenance of the regeneration of appendages based on the occurrence of severe non-lethal predation, the existence of some novel genes in regenerating organisms, and differences at the molecular level between apparently similar forms of regeneration. It is tentatively concluded that whole-body regeneration is an ancestral character although has been lost from most animal lineages. Appendage regeneration is more likely to represent a derived character resulting from many specific adaptations. © 2017 The Author.

  11. Public and Constitutional Support for Character Education.

    Science.gov (United States)

    Vessels, Gordon G.; Boyd, Stephen M.

    1996-01-01

    Character education thrives on an informed understanding of constitutional principles and an inclusive commitment-building process. U.S. Supreme Court opinions that clarify public school students' free speech rights have established values education as a constitutionally acceptable practice. Challenges might lie in possible violations of the First…

  12. Mapping wilderness character in Olympic National Park

    Science.gov (United States)

    James Tricker; Peter Landres; Jennifer Chenoweth; Roger Hoffman; Scott Ruth

    2013-01-01

    The Olympic Wilderness was established November 16, 1988 when President Ronald Reagan signed the Washington Park Wilderness Act. A total of 876,447 acres or 95% of Olympic National Park (OLYM) was designated as wilderness and became a part of the National Wilderness Preservation System, wherein wilderness character would be preserved. The purpose of this project was to...

  13. Inheritance of characters in kenaf (Hibiscus cannabinus)

    African Journals Online (AJOL)

    SERVER

    2008-04-03

    David and Adam, 1988). The plant belongs to the order Malvales, the family Malvaceae and the genus Hibiscus ... The varieties in relation to the character studied are as follows: NRG-NG-R5: Pink flowers with resistance to root ...

  14. Educating for Character in the Sexual Domain

    Science.gov (United States)

    Lickona, Thomas

    2013-01-01

    Changes in American sexual behavior brought about by the sexual revolution have been linked to the breakdown of the family and other social ills. Because sex has profound consequences for self, others, and society, sex education is an important part of character education. Sexual abstinence before marriage is associated with better physical and…

  15. Recurrent Partial Words

    Directory of Open Access Journals (Sweden)

    Francine Blanchet-Sadri

    2011-08-01

    Full Text Available Partial words are sequences over a finite alphabet that may contain wildcard symbols, called holes, which match or are compatible with all letters; partial words without holes are said to be full words (or simply words. Given an infinite partial word w, the number of distinct full words over the alphabet that are compatible with factors of w of length n, called subwords of w, refers to a measure of complexity of infinite partial words so-called subword complexity. This measure is of particular interest because we can construct partial words with subword complexities not achievable by full words. In this paper, we consider the notion of recurrence over infinite partial words, that is, we study whether all of the finite subwords of a given infinite partial word appear infinitely often, and we establish connections between subword complexity and recurrence in this more general framework.

  16. Anti-inflammatory and Antibacterial Effects of Covalently Attached Biomembrane-Mimic Polymer Grafts on Gore-Tex Implants.

    Science.gov (United States)

    Jin, Young Ju; Kang, Sunah; Park, Pona; Choi, Dongkil; Kim, Dae Woo; Jung, Dongwook; Koh, Jaemoon; Jeon, Joohee; Lee, Myoungjin; Ham, Jiyeon; Seo, Ji-Hun; Jin, Hong-Ryul; Lee, Yan

    2017-06-07

    Expanded polytetrafluoroethylene (ePTFE), also known as Gore-Tex, is widely used as an implantable biomaterial in biomedical applications because of its favorable mechanical properties and biochemical inertness. However, infection and inflammation are two major complications with ePTFE implantations, because pathogenic bacteria can inhabit the microsized pores, without clearance by host immune cells, and the limited biocompatibility can induce foreign body reactions. To minimize these complications, we covalently grafted a biomembrane-mimic polymer, poly(2-methacryloyloxylethyl phosphorylcholine) (PMPC), by partial defluorination followed by UV-induced polymerization with cross-linkers on the ePTFE surface. PMPC grafting greatly reduced serum protein adsorption as well as fibroblast adhesion on the ePTFE surface. Moreover, the PMPC-grafted ePTFE surface exhibited a dramatic inhibition of the adhesion and growth of Staphylococcus aureus, a typical pathogenic bacterium in ePTFE implants, in the porous network. On the basis of an analysis of immune cells and inflammation-related factors, i.e., transforming growth factor-β (TGF-β) and myeloperoxidase (MPO), we confirmed that inflammation was efficiently alleviated in tissues around PMPC-grafted ePTFE plates implanted in the backs of rats. Covalent PMPC may be an effective strategy for promoting anti-inflammatory and antibacterial functions in ePTFE implants and to reduce side effects in biomedical applications of ePTFE.

  17. The role of lexical variables in the visual recognition of Chinese characters: A megastudy analysis.

    Science.gov (United States)

    Sze, Wei Ping; Yap, Melvin J; Rickard Liow, Susan J

    2015-01-01

    Logographic Chinese orthography partially represents both phonology and semantics. By capturing the online processing of a large pool of Chinese characters, we were able to examine the relative salience of specific lexical variables when this nonalphabetic script is read. Using a sample of native mainland Chinese speakers (N = 35), lexical decision latencies for 1560 single characters were collated into a database, before the effects of a comprehensive range of variables were explored. Hierarchical regression analyses determined the unique item-level variance explained by orthographic (frequency, stroke count), semantic (age of learning, imageability, number of meanings), and phonological (consistency, phonological frequency) factors. Orthographic and semantic variables, respectively, accounted for more collective variance than the phonological variables. Significant main effects were further observed for the individual orthographic and semantic predictors. These results are consistent with the idea that skilled readers tend to rely on orthographic and semantic information when processing visually presented characters. This megastudy approach marks an important extension to existing work on Chinese character recognition, which hitherto has relied on factorial designs. Collectively, the findings reported here represent a useful set of empirical constraints for future computational models of character recognition.

  18. The relationships of character strengths with coping, work-related stress, and job satisfaction.

    Science.gov (United States)

    Harzer, Claudia; Ruch, Willibald

    2015-01-01

    Personality traits have often been highlighted to relate to how people cope with stressful events. The present paper focuses on character strengths as positive personality traits and examines two basic assumptions that were derived from a core characteristic of character strengths (i.e., to determine how individuals deal with adversities): (1) character strengths correlate with coping and (2) buffer the effects of work-related stress on job satisfaction. Two different samples (i.e., a mixed sample representing various occupations [N = 214] and a nurses sample [N = 175]) filled in measures for character strengths, coping, work-related stress, and job satisfaction. As expected, intellectual, emotional, and interpersonal strengths were related to coping. Interpersonal strengths played a greater role for coping among nurses, as interactions with others are an essential part of their workday. Furthermore, intellectual strengths partially mediated the negative effect of work-related stress on job satisfaction. These findings open a new field for research on the role of personality in coping with work-related stress. Character strengths are trainable personal characteristics, and therefore valuable resources to improve coping with work-related stress and to decrease the negative effects of stress. Further research is needed to investigate this assumed causality.

  19. The relationships of character strengths with coping, work-related stress, and job satisfaction

    Directory of Open Access Journals (Sweden)

    Claudia eHarzer

    2015-02-01

    Full Text Available Personality traits have often been highlighted to relate to how people cope with stressful events. The present paper focuses on character strengths as positive personality traits and examines two basic assumptions that were derived from a core characteristic of character strengths (i.e., to determine how individuals deal with adversities: (1 Character strengths correlate with coping and (2 buffer the effects of work-related stress on job satisfaction. Two different samples (i.e., a mixed sample representing various occupations [N = 214] and a nurses sample [N = 175] filled in measures for character strengths, coping, work-related stress, and job satisfaction. As expected, intellectual, emotional, and interpersonal strengths were related to coping. Interpersonal strengths played a greater role for coping among nurses, as interactions with others are an essential part of their workday. Furthermore, intellectual strengths partially mediated the negative effect of work-related stress on job satisfaction. These findings open a new field for research on the role of personality in coping with work-related stress. Character strengths are trainable personal characteristics, and therefore valuable resources to improve coping with work-related stress and to decrease the negative effects of stress. Further research is needed to investigate this assumed causality.

  20. Mechanism of the Topotactic Formation of gamma-Zirconium Phosphate Covalently Pillared with Diphosphonate Groups.

    Science.gov (United States)

    Alberti, G.; Giontella, E.; Murcia-Mascarós, S.; Vivani, R.

    1998-09-07

    The topotactic reaction of gamma-ZrPO(4)[O(2)P(OH)(2)].2H(2)O (gamma-ZrP) with benzenediphosphonic acid was examined in water and in acetone-water mixtures. This reaction was found to take place in water only on the external surface of the microcrystals, and pillared compounds were never obtained, even after very long reaction times. On the contrary, covalently pillared compounds were quickly obtained in acetone-water mixtures. The mechanism of the latter topotactic reaction was investigated by determining the rate of the phosphate groups released and the rate of the benzenediphosphonates taken up by gamma-ZrP over a long time (50 days). These data showed that pillared derivatives of gamma-ZrP can be obtained because colloidal dispersions of exfoliated lamellae are formed in acetone-water mixtures. The diphosphonate group acts initially as a monovalent species, replacing only one dihydrogen phosphate group on the surface of the exfoliated gamma-lamellae. The colloidal and partially derivatized lamellae thus formed can interact with each other by forming polylamellar pillared systems. When the number of pillared lamellae exceeds a given value (usually 5-6), flocculation of the colloidal gamma-ZrP takes place. Topotactic reactions between packets of pillared lamellae may also continue in the flocculated system. Therefore, the average number of the pillared lamellae slowly increases over time.

  1. Review: peripheral nerve regeneration using non-tubular alginate gel crosslinked with covalent bonds.

    Science.gov (United States)

    Hashimoto, Tadashi; Suzuki, Yoshihisa; Suzuki, Kyoko; Nakashima, Toshihide; Tanihara, Masao; Ide, Chizuka

    2005-06-01

    We have developed a nerve regeneration material consisting of alginate gel crosslinked with covalent bonds. in the first part of this study, we attempted to analyze nerve regeneration through alginate gel in the early stages within 2 weeks. in the second part, we tried to regenerate cat peripheral nerve by using alginate tubular or non-tubular nerve regeneration devices, and compared their efficacies. Four days after surgery, regenerating axons grew without Schwann cell investment through the partially degraded alginate gel, being in direct contact with the alginate without a basal lamina covering. One to 2 weeks after surgery, regenerating axons were surrounded by common Schwann cells, forming small bundles, with some axons at the periphery being partly in direct contact with alginate. At the distal stump, numerous Schwann cells had migrated into the alginate 8-14 days after surgery. Remarkable restorations of the 50-mm gap in cat sciatic nerve were obtained after a long term by using tubular or non-tubular nerve regeneration material consisting mainly of alginate gel. However, there was no significant difference between both groups at electrophysiological and morphological evaluation. Although, nowadays, nerve regeneration materials being marketed mostly have a tubular structure, our results suggest that the tubular structure is not indispensable for peripheral nerve regeneration.

  2. Molecular single-bond covalent radii for elements 1-118.

    Science.gov (United States)

    Pyykkö, Pekka; Atsumi, Michiko

    2009-01-01

    A self-consistent system of additive covalent radii, R(AB)=r(A) + r(B), is set up for the entire periodic table, Groups 1-18, Z=1-118. The primary bond lengths, R, are taken from experimental or theoretical data corresponding to chosen group valencies. All r(E) values are obtained from the same fit. Both E-E, E-H, and E-CH(3) data are incorporated for most elements, E. Many E-E' data inside the same group are included. For the late main groups, the system is close to that of Pauling. For other elements it is close to the methyl-based one of Suresh and Koga [J. Phys. Chem. A 2001, 105, 5940] and its predecessors. For the diatomic alkalis MM' and halides XX', separate fits give a very high accuracy. These primary data are then absorbed with the rest. The most notable exclusion are the transition-metal halides and chalcogenides which are regarded as partial multiple bonds. Other anomalies include H(2) and F(2). The standard deviation for the 410 included data points is 2.8 pm.

  3. Films of covalently bonded gold nanoparticles synthesized by a sol–gel process

    International Nuclear Information System (INIS)

    Dell’Erba, Ignacio E.; Hoppe, Cristina E.; Williams, Roberto J. J.

    2012-01-01

    Gold nanoparticles (NPs) with a size close to 1.5 nm, coated with organic ligands bearing Si(OEt) 3 groups, were synthesized and used to obtain self-standing films by a sol–gel process catalyzed by formic acid. Using FESEM images, FTIR, and UV–visible spectra, it was observed that very small gold NPs self-assembled by Si–O–Si covalent bonds forming crosslinked clusters with sizes up to about 50 nm in which NPs preserve their individuality. The possibility of fixing very small gold NPs in a crosslinked film opens a variety of potential applications based on the specific properties of small-size particles. As an example, we illustrated the way in which one can take advantage of the low melting temperature of these NPs to generate tiny gold crystals partially embedded at the surface, a process that might be used for the development of catalysts or sensors. Besides, the shift and change in the intensity of the plasmon band produced by heating to 100 °C may be employed to develop an irreversible sensor of undesirable temperature excursions during the life-time of a specific product.

  4. Kurzweil Reading Machine: A Partial Evaluation of Its Optical Character Recognition Error Rate.

    Science.gov (United States)

    Goodrich, Gregory L.; And Others

    1979-01-01

    A study designed to assess the ability of the Kurzweil reading machine (a speech reading device for the visually handicapped) to read three different type styles produced by five different means indicated that the machines tested had different error rates depending upon the means of producing the copy and upon the type style used. (Author/CL)

  5. Contribution to automatic handwritten characters recognition. Application to optical moving characters recognition

    International Nuclear Information System (INIS)

    Gokana, Denis

    1986-01-01

    This paper describes a research work on computer aided vision relating to the design of a vision system which can recognize isolated handwritten characters written on a mobile support. We use a technique which consists in analyzing information contained in the contours of the polygon circumscribed to the character's shape. These contours are segmented and labelled to give a new set of features constituted by: - right and left 'profiles', - topological and algebraic unvarying properties. A new method of character's recognition induced from this representation based on a multilevel hierarchical technique is then described. In the primary level, we use a fuzzy classification with dynamic programming technique using 'profiles'. The other levels adjust the recognition by using topological and algebraic unvarying properties. Several results are presented and an accuracy of 99 pc was reached for handwritten numeral characters, thereby attesting the robustness of our algorithm. (author) [fr

  6. Covalent Organic Framework Electrocatalysts for Clean Energy Conversion.

    Science.gov (United States)

    Lin, Chun-Yu; Zhang, Detao; Zhao, Zhenghang; Xia, Zhenhai

    2018-02-01

    Covalent organic frameworks (COFs) are promising for catalysis, sensing, gas storage, adsorption, optoelectricity, etc. owning to the unprecedented combination of large surface area, high crystallinity, tunable pore size, and unique molecular architecture. Although COFs are in their initial research stage, progress has been made in the design and synthesis of COF-based electrocatalysis for the oxygen reduction reaction, oxygen evolution reaction, hydrogen evolution reaction, and CO 2 reduction in energy conversion and fuel generation. Design principles are also established for some of the COF materials toward rational design and rapid screening of the best electrocatalysts for a specific application. Herein, the recent advances in the design and synthesis of COF-based catalysts for clean energy conversion and storage are presented. Future research directions and perspectives are also being discussed for the development of efficient COF-based electrocatalysts. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  7. Non-Covalent Organocatalyzed Domino Reactions Involving Oxindoles: Recent Advances

    Directory of Open Access Journals (Sweden)

    Tecla Gasperi

    2017-09-01

    Full Text Available The ubiquitous presence of spirooxindole architectures with several functionalities and stereogenic centers in bioactive molecules has been appealing for the development of novel methodologies seeking their preparation in high yields and selectivities. Expansion and refinement in the field of asymmetric organocatalysis have made possible the development of straightforward strategies that address these two requisites. In this review, we illustrate the current state-of-the-art in the field of spirooxindole synthesis through the use of non-covalent organocatalysis. We aim to provide a concise overview of very recent methods that allow to the isolation of unique, densely and diversified spirocyclic oxindole derivatives with high structural diversity via the use of cascade, tandem and domino processes.

  8. Near universal support for covalent immobilisation of enzymes for biotechnology

    International Nuclear Information System (INIS)

    Elnashar, M.M.; Millner, P.A.; Gibson, T.D.

    2005-01-01

    Carrageenan [1], natural polymer, has been modified to be used as a universal/near universal support to immobilise enzymes, where the gel remained stable at 70 degree C for 24 h at a wide range of buffers and ph s and its mechanical strength was 400% greater than the unmodified gel. The new matrix successfully immobilised covalently eight commercially used enzymes including hydrolases, Upases, oxidoreductases, proteases and dehydrogenases. It also acted as a self buffering system in case of hydrolases and stopped enzyme's product inhibition. The apparent Km values of immobilised enzymes were found in many cases to be much less than those of the free enzymes. Another interesting correlation was observed where the great lowering of the apparent Km with immobilised enzymes was directly proportional to the substrate molecular weight. In economic terms, the new matrix is at least two orders of magnitude cheaper than supports such as Eupergit C

  9. Electronic basis of hardness and phase transformations (covalent crystals)

    International Nuclear Information System (INIS)

    Gilman, J J

    2008-01-01

    Several electronic parameters measure the stabilities of covalent crystals, including minimum energy band-gap densities, inverse polarizabilities, plasma frequencies, transverse vibrational frequencies and elastic shear moduli. Convenient is the band-gap density (energy/volume; called the 'bond modulus'). For a given bonding type, the indentation hardness is proportional to the bond modulus. Examples are the group IV elements, III-V compounds; and II-VI compounds. The motion of dislocation kinks requires the excitation of bonding electrons into anti-bonding states. The bond modulus measures this together with the work done by the applied stress when a kink moves. In addition to hardness, the bond modulus measures the compressive strain (pressure) needed to transform an ambient structure into a more dense structure. Activation of such transformations also requires the excitation of bonding electrons into anti-bonding states together with the work done by the compressive stress

  10. Biofunctional paper via the covalent modification of cellulose.

    Science.gov (United States)

    Yu, Arthur; Shang, Jing; Cheng, Fang; Paik, Bradford A; Kaplan, Justin M; Andrade, Rodrigo B; Ratner, Daniel M

    2012-07-31

    Paper-based analytical devices are the subject of growing interest for the development of low-cost point-of-care diagnostics, environmental monitoring technologies, and research tools for limited-resource settings. However, there are limited chemistries available for the conjugation of biomolecules to cellulose for use in biomedical applications. Herein, divinyl sulfone (DVS) chemistry was demonstrated to immobilize small molecules, proteins, and DNA covalently onto the hydroxyl groups of cellulose membranes through nucleophilic addition. Assays on modified cellulose using protein-carbohydrate and protein-glycoprotein interactions as well as oligonucleotide hybridization showed that the membrane's bioactivity was specific, dose-dependent, and stable over a long period of time. The use of an inkjet printer to form patterns of biomolecules on DVS-activated cellulose illustrates the adaptability of the DVS functionalization technique to pattern sophisticated designs, with potential applications in cellulose-based lateral flow devices.

  11. Covalent bond orders and atomic valences from correlated wavefunctions

    Science.gov (United States)

    Ángyán, János G.; Rosta, Edina; Surján, Péter R.

    1999-01-01

    A comparison is made between two alternative definitions for covalent bond orders: one derived from the exchange part of the two-particle density matrix and the other expressed as the correlation of fluctuations (covariance) of the number of electrons between the atomic centers. Although these definitions lead to identical formulae for mono-determinantal SCF wavefunctions, they predict different bond orders for correlated wavefunctions. It is shown that, in this case, the fluctuation-based definition leads to slightly lower values of the bond order than does the exchange-based definition, provided one uses an appropriate space-partitioning technique like that of Bader's topological theory of atoms in a molecule; however, use of Mulliken partitioning in this context leads to unphysical behaviour. The example of H 2 is discussed in detail.

  12. Photoreversible Covalent Hydrogels for Soft-Matter Additive Manufacturing.

    Science.gov (United States)

    Kabb, Christopher P; O'Bryan, Christopher S; Deng, Christopher C; Angelini, Thomas E; Sumerlin, Brent S

    2018-05-16

    Reversible covalent chemistry provides access to robust materials with the ability to be degraded and reformed upon exposure to an appropriate stimulus. Photoresponsive units are attractive for this purpose, as the spatial and temporal application of light is easily controlled. Coumarin derivatives undergo a [2 + 2] cycloaddition upon exposure to long-wave UV irradiation (365 nm), and this process can be reversed using short-wave UV light (254 nm). Therefore, polymers cross-linked by coumarin groups are excellent candidates as reversible covalent gels. In this work, copolymerization of coumarin-containing monomers with the hydrophilic comonomer N, N-dimethylacrylamide yielded water-soluble, linear polymers that could be cured with long-wave UV light into free-standing hydrogels, even in the absence of a photoinitiator. Importantly, the gels were reverted back to soluble copolymers upon short-wave UV irradiation. This process could be cycled, allowing for recycling and remolding of the hydrogel into additional shapes. Further, this hydrogel can be imprinted with patterns through a mask-based, post-gelation photoetching method. Traditional limitations of this technique, such as the requirement for uniform etching in one direction, have been overcome by combining these materials with a soft-matter additive manufacturing methodology. In a representative application of this approach, we printed solid structures in which the interior coumarin-cross-linked gel is surrounded by a nondegradable gel. Upon exposure to short-wave UV irradiation, the coumarin-cross-linked gel was reverted to soluble prepolymers that were washed away to yield hollow hydrogel objects.

  13. Covalent DNA-protein crosslinking occurs after hyperthermia and radiation

    International Nuclear Information System (INIS)

    Cress, A.E.; Bowden, G.T.

    1983-01-01

    Covalent DNA-protein crosslinks occur in exponentially growing mouse leukemia cells (L1210) after exposure to ionizing radiation. The amount of DNA-protein crosslinks as measured by a filter binding assay is dose dependent upon x irradiation. Although hyperthermia and radiation in combination are synergistic with respect to cell lethality, the combination does not result in an increase of DNA-protein crosslinks when assayed immediately following treatments. Hyperthermia (43 0 C/15 min) given prior to radiation dose not alter the radiation dose dependency of the amount of initial crosslinking. In addition, the amount of DNA-protein crosslinking produced by heat plus radiation is independent of the length of heating the cells at 43 0 C. The DNA-protein crosslinks produced y 50-Gy x ray alone are removed after 2 hr at 37 0 C. However, if hyperthermia (43 0 C/15 min) is given prior to 100-Gy x ray, the removal of DNA-protein crosslinks is delayed until 4.0 hr after radiation. Phospho-serine and phospho-threonine bonds are not produced with either radiation or the combination of hyperthermia plus radiation as judged by the resistance of the bonds to guanidine hydrochloride. However, hyperthermia plus radiation causes an increase in phosphate to nitrogen type bonding. These results show that radiation alone causes covalent DNA-protein crosslinks. Hyperthermia in combination with radiation does not increase the total amount of the crosslinks but delays the removal of the crosslinks and alters the distribution of the types of chemical bonding

  14. Cultivating characters (moral value) through internalization strategy in science classroom

    Science.gov (United States)

    Ibrahim, M.; Abadi

    2018-01-01

    It is still in a crucial debate that characters play an important learning outcome to be realized by design. So far, most people think that characters were reached as nurturance effect with the assumption that students who are knowledgeable and skillful will have good characters automatically. Lately, obtained evidence that this assumption is not true. Characters should be taught deliberately or by design. This study was designed to culture elementary school students’ characters through science classroom. The teaching-learning process was conducted to facilitate and bridge the students from the known (concrete images: Science phenomena) to the unknown (abstract ideas: characters: care, and tolerance. Characters were observed five weeks before and after the intervention. Data were analyzed from observation of 24 students in internalization strategy-based courses. Qualitative and quantitative data suggested that the internalization strategy that use of science phenomena to represent abstract ideas (characters) in science classroom positively cultivating characters.

  15. Seismic echo character northern Hatteras Abyssal Plain

    International Nuclear Information System (INIS)

    McCreery, C.J.; Laine, E.P.

    1985-01-01

    Latest efforts in echo-character mapping of the northern Hatteras Abyssal Plain have discerned variations in thickness in a near-surface sedimentary sequence which has been designated seismic unit A. This unit probably represents the last episode of progradation of the Hatteras Deep Sea Fan in the southern part of the study area, and has infilled probable paleochannels from the Wilmington Canyon and Sohm Gap in the north. Unit A thins to a minimum in the central part of the plain, where older sediments come within 1 meter of the surface. Variations in the character of the surface reflector probably represent differing degrees of microtopography developed on a Late Pleistocene surface overlain by Holocene sediments. With the exception of one area identified as a relict surface outcropping in the western plain, this microtopography seems related to present-day thalweg locations on the abyssal plain. 11 references, 13 figures

  16. On the total character of finite groups

    Directory of Open Access Journals (Sweden)

    Sunil Kumar Prajapati

    2014-09-01

    Full Text Available For a finite group $G$, we study the total character $tau_G$ afforded by the direct sum of all the non-isomorphic irreducible complex representations of $G$. We resolve for several classes of groups (the Camina $p$-groups, the generalized Camina $p$-groups, the groups which admit $(G,Z(G$ as a generalized Camina pair, the problem of existence of a polynomial $f(x in mathbb{Q}[x]$ such that $f(chi = tau_G$ for some irreducible character $chi$ of $G$. As a consequence, we completely determine the $p$-groups of order at most $p^5$ (with $p$ odd which admit such a polynomial. We deduce the characterization that these are the groups $G$ for which $Z(G$ is cyclic and $(G,Z(G$ is a generalized Camina pair and, we conjecture that this holds good for $p$-groups of any order.

  17. The Character, Organization Change and Information System

    Directory of Open Access Journals (Sweden)

    Santo Fernandi Wijaya

    2011-06-01

    Full Text Available The success of building an integrated information system is an expectation of every company management to achieve effective and efficient working system. However, in the real business practices, not a few companies failed in building an integrated information system caused by the absence of several factors: strong commitment, hard work and smart effort conducted by a team. The team determines the success level in building an integrated information system. A factor of intelligence and mental maturity of users in running a new information system that has not been known is also another key to success. Therefore, it takes a good user’s character supported by a management decision to make management changes to achieve the building success level. This study aims to address the role of character and organization changes in achieving a success building an integrated information system. 

  18. Correlators in tensor models from character calculus

    Directory of Open Access Journals (Sweden)

    A. Mironov

    2017-11-01

    Full Text Available We explain how the calculations of [20], which provided the first evidence for non-trivial structures of Gaussian correlators in tensor models, are efficiently performed with the help of the (Hurwitz character calculus. This emphasizes a close similarity between technical methods in matrix and tensor models and supports a hope to understand the emerging structures in very similar terms. We claim that the 2m-fold Gaussian correlators of rank r tensors are given by r-linear combinations of dimensions with the Young diagrams of size m. The coefficients are made from the characters of the symmetric group Sm and their exact form depends on the choice of the correlator and on the symmetries of the model. As the simplest application of this new knowledge, we provide simple expressions for correlators in the Aristotelian tensor model as tri-linear combinations of dimensions.

  19. Optical Character Recognition: Application for Android

    OpenAIRE

    Gonzalez Manzanero, Joaquin Miguel

    2013-01-01

    Treball realitzat a Tongji University El projecte és el desenvolupament d'una aplicació per Android basat en OCR(Optical Character Recognition) que consisteix en traduir frases d'un idioma a un altre a través de fotografiar el text amb el mòbil, després reconéixer els caràcters i finalment traduïnt al llenguatge desitjat.

  20. Hybrid Motion Graphs for Character Animation

    OpenAIRE

    Kalouache Saida; Cherif Foudil

    2016-01-01

    Many works in the literature have improved the performance of motion graphs for synthesis the humanlike results in limited domains that necessity few constraints like dance, navigation in small game like environments or in games by the gesture of feedback on a snowboard tutorial. The humanlike cannot exist in an environment without interacting with the world surrounding them; the naturalness of the entire motion extremely depends on the animation of the walking character, the chosen path and ...

  1. Font generation of personal handwritten Chinese characters

    Science.gov (United States)

    Lin, Jeng-Wei; Wang, Chih-Yin; Ting, Chao-Lung; Chang, Ray-I.

    2014-01-01

    Today, digital multimedia messages have drawn more and more attention due to the great achievement of computer and network techniques. Nevertheless, text is still the most popular media for people to communicate with others. Many fonts have been developed so that product designers can choose unique fonts to demonstrate their idea gracefully. It is commonly believed that handwritings can reflect one's personality, emotion, feeling, education level, and so on. This is especially true in Chinese calligraphy. However, it is not easy for ordinary users to customize a font of their personal handwritings. In this study, we performed a process reengineering in font generation. We present a new method to create font in a batch mode. Rather than to create glyphs of characters one by one according to their codepoints, people create glyphs incrementally in an on-demand manner. A Java Implementation is developed to read a document image of user handwritten Chinese characters, and make a vector font of these handwritten Chinese characters. Preliminary experiment result shows that the proposed method can help ordinary users create their personal handwritten fonts easily and quickly.

  2. Vocal analysis of suicidal movie characters.

    Science.gov (United States)

    Palinkas-Sanches, Elaine; Sanches, Marsal; Ferrari, Maria Cristina C; Oliveira, Gisele; Behlau, Mara

    2010-12-01

    The aim of this study was to describe the auditory-perceptive evaluation and the psychodynamic aspects of voice samples among suicidal movie characters. Voice samples of 48 characters (27 male, 21 female), extracted from 36 movies produced between 1968 and 2006, were analyzed. The samples were evaluated through a specific protocol focusing on the auditory-perceptive evaluation (voice quality, resonance, pitch, loudness, modulation, pauses, articulation and rhythm) and the psychodynamic aspects of voice. 85.5% of the samples exhibited abnormal findings in at least five parameters of the auditory-perceptive analysis, such as breathiness (n=42; 87.5% of the samples), hoarseness (n=39; 81.2%) and strain (n=29; 60.4%), as well as laryngopharingeal resonance (n=39; 81.2%), either high pitch (n=14; 29.2%), or decreased loudness (n=31; 64.6%). With respect to the psychodynamic aspects, dismay was detected in 50% (n=24) of the samples, hopelessness in 47.9% (n=23), resignation in 37.5% (n=18), and sadness in 33.3% (n=16). Our findings suggest the existence of specific patterns used by actors during the interpretation of suicidal characters. The replication of these findings among real patients may contribute to improvement in the evaluation of potential suicidal patients, as well as the implementation of preventive measures.

  3. Covalent cross-linking of insulin-like growth factor-1 to a specific inhibitor from human serum

    International Nuclear Information System (INIS)

    Ooi, G.T.; Herington, A.C.

    1986-01-01

    Previous studies have shown that a specific inhibitor of insulin-like growth factor (IGF) action in vitro can be isolated from normal human serum and subsequently partially purified on an IGF-affinity column. The ability of the inhibitor to bind the IGFs has now been confirmed directly using covalent cross-linking techniques. When 125 I-IGF-1 was cross-linked to inhibitor using disuccinimidyl suberate, five specifically labelled bands were seen on SDS-PAGE and autoradiography. Two bands (MW 21.5 K and 25.5 K) were intensely labelled, while the remaining three (MW 37 K, 34 K and 18 K) appeared as minor bands only. Inhibitor bioactivity, following further analysis by hydrophobic interaction chromatography or Con A-Sepharose affinity chromatography, was always associated with the presence of the 21.5 K and/or 25.5 K bands

  4. Covalent-ionically cross-linked polyetheretherketone proton exchange membrane for direct methanol fuel cell

    CSIR Research Space (South Africa)

    Luo, H

    2010-08-01

    Full Text Available cross-linked PEEK-WC membrane, this covalent-ionically cross-linked PEEK-WC membrane exhibits extremely reduced water uptake and methanol permeability, but just slightly sacrificed proton conductivity. The proton conductivity of the covalent...

  5. Covalently bound conjugates of albumin and heparin: Synthesis, fractionation and characterization

    NARCIS (Netherlands)

    Hennink, Wim E.; Feijen, Jan; Ebert, Charles D.; Kim, Sung Wan

    1983-01-01

    Covalently bound conjugates of human serum albumin and heparin were prepared as compounds which could improve the blood-compatibility of polymer surfaces either by preadsorption or by covalent coupling of the conjugates onto blood contacting surfaces. The conjugates (10–16 weight % of heparin) were

  6. Covalently Immobilised Cytochrome C Imaged by In Situ Scanning Tunnelling Microscopy

    DEFF Research Database (Denmark)

    Andersen, Jens Enevold Thaulov; Olesen, Klaus G.; Danilov, Alexey I.

    1997-01-01

    In situ scanning tunnelling microscopy (STM) imaging of cytochrome c (cyt c) on polycrystalline Pt surfaces and on Au(lll) was achieved first by covalent immobilisation of 3-aminopropyltriethoxysilane (3-APTS) brought to react with oxide present on the Pt surfaces. Covalently bound 3-APTS forms...

  7. Application of the Covalent Bond Classification Method for the Teaching of Inorganic Chemistry

    Science.gov (United States)

    Green, Malcolm L. H.; Parkin, Gerard

    2014-01-01

    The Covalent Bond Classification (CBC) method provides a means to classify covalent molecules according to the number and types of bonds that surround an atom of interest. This approach is based on an elementary molecular orbital analysis of the bonding involving the central atom (M), with the various interactions being classified according to the…

  8. The role of double covalent flavin binding in chito-oligosaccharide oxidase from Fusarium graminearum

    NARCIS (Netherlands)

    Heuts, Dominic P. H. M.; Winter, Remko T.; Damsma, Gerke E.; Janssen, Dick B.; Fraaije, Marco W.

    2008-01-01

    ChitO (chito-oligosaccharide oxidase) from Fusarium graminearum catalyses the regioselective oxidation of N-acetylated oligosaccharides. The enzyme harbours an FAD cofactor that is covalently attached to His(94) and Cys(154). The functional role of this unusual bi-covalent flavin-protein linkage was

  9. Optical character recognition based on nonredundant correlation measurements.

    Science.gov (United States)

    Braunecker, B; Hauck, R; Lohmann, A W

    1979-08-15

    The essence of character recognition is a comparison between the unknown character and a set of reference patterns. Usually, these reference patterns are all possible characters themselves, the whole alphabet in the case of letter characters. Obviously, N analog measurements are highly redundant, since only K = log(2)N binary decisions are enough to identify one out of N characters. Therefore, we devised K reference patterns accordingly. These patterns, called principal components, are found by digital image processing, but used in an optical analog computer. We will explain the concept of principal components, and we will describe experiments with several optical character recognition systems, based on this concept.

  10. Head capsule characters in the Hymenoptera and their phylogenetic implications

    Directory of Open Access Journals (Sweden)

    Lars Vilhelmsen

    2011-09-01

    Full Text Available The head capsule of a taxon sample of three outgroup and 86 ingroup taxa is examined for characters of possible phylogenetic significance within Hymenoptera. 21 morphological characters are illustrated and scored, and their character evolution explored by mapping them onto a phylogeny recently produced from a large morphological data set. Many of the characters are informative and display unambiguous changes. Most of the character support demonstrated is supportive at the superfamily or family level. In contrast, only few characters corroborate deeper nodes in the phylogeny of Hymenoptera.

  11. Leadership, character and its development: A qualitative exploration

    Directory of Open Access Journals (Sweden)

    Roslyn de Braine

    2007-11-01

    Full Text Available The purpose of this study was to explore (1 what organisational leaders consider to be character elements of leaders within the workplace, (2 what influences leaders’ character development, and (3 how an organisation can continue the process of character development. The literature review and findings revealed that leadership, integrity, industriousness, empathy, loyalty, optimism, fairness and compassion are the most sought after character elements within leaders in the workplace. Leadership and integrity were found to be the most supported character elements. The findings also indicate that work environmental factors, a person’s own efforts, and the daily experiences of work life contribute towards character development.

  12. Dynamic Covalent Chemistry within Biphenyl Scaffolds: Reversible Covalent Bonding, Control of Selectivity, and Chirality Sensing with a Single System.

    Science.gov (United States)

    Ni, Cailing; Zha, Daijun; Ye, Hebo; Hai, Yu; Zhou, Yuntao; Anslyn, Eric V; You, Lei

    2018-01-26

    Axial chirality is a prevalent and important phenomenon in chemistry. Herein we report a combination of dynamic covalent chemistry and axial chirality for the development of a versatile platform for the binding and chirality sensing of multiple classes of mononucleophiles. An equilibrium between an open aldehyde and its cyclic hemiaminal within biphenyl derivatives enabled the dynamic incorporation of a broad range of alcohols, thiols, primary amines, and secondary amines with high efficiency. Selectivity toward different classes of nucleophiles was also achieved by regulating the distinct reactivity of the system with external stimuli. Through induced helicity as a result of central-to-axial chirality transfer, the handedness and ee values of chiral monoalcohol and monoamine analytes were reported by circular dichroism. The strategies introduced herein should find application in many contexts, including assembly, sensing, and labeling. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. A novel handwritten character recognition system using gradient ...

    Indian Academy of Sciences (India)

    The issues faced by the handwritten character recognition systems are the similarity. ∗ ... tical/structural features have also been successfully used in character ..... The coordinates (xc, yc) of centroid are calculated by equations (4) and (5). xc =.

  14. Animated Character Analysis and Costume Design with Structured Analysis

    OpenAIRE

    Yıldırım Artaç, Berna; Ağaç, Saliha

    2016-01-01

    In various genres, costumes complement fictional characters and not onlyconstitute the external appearance of the fictional character, but are alsoused for purposes of fun or style by fans who dress up as the character andinternalize that character’s state of mind. This phenomenon is calledcosplay. A literature review of the field has revealed no study made previouslyon the cosplay costume design process according to character analysis. Thepresent study emphasizes the link between an...

  15. Dynamic Obstacle Clearing for Real-time Character Animation

    OpenAIRE

    Glardon, Pascal; Boulic, Ronan; Thalmann, Daniel

    2006-01-01

    This paper proposes a novel method to control virtual characters in dynamic environments. A virtual character is animated by a locomotion and jumping engine, enabling production of continuous parameterized motions. At any time during runtime, flat obstacles (e.g. a puddle of water) can be created and placed in front of a character. The method first decides whether the character is able to get around or jump over the obstacle. Then the motion parameters are accordingly modified. The transition...

  16. Integrating Character Education In Teaching Speaking For Business Administration Students

    OpenAIRE

    Woro Prastiwi, Chyntia Heru

    2016-01-01

    Globalization along with the advancement of information and communication technology has brought tremendous effects on students' character. Education field as a place of community has to contribute in developing students' character traits. Integrating character education in curriculum is the key for qualified education. This research aimed to describe the way to integrate character education in teaching speaking for Business Administration students. The data was obtained from teaching and lea...

  17. The Character Strengths of Class Clowns

    Directory of Open Access Journals (Sweden)

    Willibald F. Ruch

    2014-09-01

    Full Text Available Class clowns traditionally were studied as a type concept and identified via sociometric procedures. In the present study a variable-centered approach was favored and class clown behaviors were studied in the context of character strengths, orientations to happiness and satisfaction with life. A sample of 672 Swiss children and adolescents filled in an 18 item self-report instrument depicting class clown behaviors. A hierarchical model of class clown behaviors was developed distinguishing a general factor and the four positively correlated dimensions of identified as a class clown, comic talent, disruptive rule-breaker, and subversive joker. Analysis of the general factor showed that class clowns were primarily male, and tended to be seen as class clowns by the teacher. Analyses of the 24 character strengths of the VIA-Youth (Park & Peterson, 2006 showed that class clowns were high in humor and leadership, and low in strengths like prudence, self-regulation, modesty, honesty, fairness, perseverance, and love of learning. An inspection of signature strengths revealed that 75% of class clowns had humor as a signature strength. Furthermore, generally class clown behaviors were shown by students indulging in a life of pleasure, but low life of engagement. The four dimensions yielded different character strengths profiles. While all dimensions of class clowns behaviors were low in temperance strengths, the factors identified as the class clown and comic talent were correlated with leadership strengths and the two negative factors (disruptive rule-breaker, subversive joker were low in other directed strengths. The disruptive rule breaking class clown was additionally low in intellectual strengths. While humor predicted life satisfaction, class clowning tended to go along with diminished satisfaction with life. It is concluded that different types of class clowns need to be kept apart and need different attention by teachers.

  18. The character strengths of class clowns.

    Science.gov (United States)

    Ruch, Willibald; Platt, Tracey; Hofmann, Jennifer

    2014-01-01

    Class clowns traditionally were studied as a type concept and identified via sociometric procedures. In the present study a variable-centered approach was favored and class clown behaviors were studied in the context of character strengths, orientations to happiness and satisfaction with life. A sample of 672 Swiss children and adolescents filled in an 18 item self-report instrument depicting class clown behaviors. A hierarchical model of class clown behaviors was developed distinguishing a general factor and the four positively correlated dimensions of "identified as a class clown," "comic talent," "disruptive rule-breaker," and "subversive joker." Analysis of the general factor showed that class clowns were primarily male, and tended to be seen as class clowns by the teacher. Analyses of the 24 character strengths of the VIA-Youth (Park and Peterson, 2006) showed that class clowns were high in humor and leadership, and low in strengths like prudence, self-regulation, modesty, honesty, fairness, perseverance, and love of learning. An inspection of signature strengths revealed that 75% of class clowns had humor as a signature strength. Furthermore, class clown behaviors were generally shown by students indulging in a life of pleasure, but low life of engagement. The four dimensions yielded different character strengths profiles. While all dimensions of class clowns behaviors were low in temperance strengths, the factors "identified as the class clown" and "comic talent" were correlated with leadership strengths and the two negative factors ("disruptive rule-breaker," "subversive joker") were low in other directed strengths. The disruptive rule breaking class clown was additionally low in intellectual strengths. While humor predicted life satisfaction, class clowning tended to go along with diminished satisfaction with life. It is concluded that different types of class clowns need to be kept apart and need different attention by teachers.

  19. Hyperbolic partial differential equations

    CERN Document Server

    Witten, Matthew

    1986-01-01

    Hyperbolic Partial Differential Equations III is a refereed journal issue that explores the applications, theory, and/or applied methods related to hyperbolic partial differential equations, or problems arising out of hyperbolic partial differential equations, in any area of research. This journal issue is interested in all types of articles in terms of review, mini-monograph, standard study, or short communication. Some studies presented in this journal include discretization of ideal fluid dynamics in the Eulerian representation; a Riemann problem in gas dynamics with bifurcation; periodic M

  20. Successful removable partial dentures.

    Science.gov (United States)

    Lynch, Christopher D

    2012-03-01

    Removable partial dentures (RPDs) remain a mainstay of prosthodontic care for partially dentate patients. Appropriately designed, they can restore masticatory efficiency, improve aesthetics and speech, and help secure overall oral health. However, challenges remain in providing such treatments, including maintaining adequate plaque control, achieving adequate retention, and facilitating patient tolerance. The aim of this paper is to review the successful provision of RPDs. Removable partial dentures are a successful form of treatment for replacing missing teeth, and can be successfully provided with appropriate design and fabrication concepts in mind.

  1. Beginning partial differential equations

    CERN Document Server

    O'Neil, Peter V

    2011-01-01

    A rigorous, yet accessible, introduction to partial differential equations-updated in a valuable new edition Beginning Partial Differential Equations, Second Edition provides a comprehensive introduction to partial differential equations (PDEs) with a special focus on the significance of characteristics, solutions by Fourier series, integrals and transforms, properties and physical interpretations of solutions, and a transition to the modern function space approach to PDEs. With its breadth of coverage, this new edition continues to present a broad introduction to the field, while also addres

  2. On character amenability of Banach algebras

    Science.gov (United States)

    Kaniuth, E.; Lau, A. T.; Pym, J.

    2008-08-01

    We continue our work [E. Kaniuth, A.T. Lau, J. Pym, On [phi]-amenability of Banach algebras, Math. Proc. Cambridge Philos. Soc. 144 (2008) 85-96] in the study of amenability of a Banach algebra A defined with respect to a character [phi] of A. Various necessary and sufficient conditions of a global and a pointwise nature are found for a Banach algebra to possess a [phi]-mean of norm 1. We also completely determine the size of the set of [phi]-means for a separable weakly sequentially complete Banach algebra A with no [phi]-mean in A itself. A number of illustrative examples are discussed.

  3. ZBrush Character Creation Advanced Digital Sculpting

    CERN Document Server

    Spencer, Scott

    2011-01-01

    A stunning, content-rich update to this top-selling ZBrush guide! This second edition of ZBrush Character Creation has been fully updated for ZBrush 4, the newest version of this fascinating and popular 3D sculpting software. ZBrush enables users to create detailed organic models using a brush-based toolset and tablet. The startling results look as though they've been painted with real brushes and oils, and ZBrush is increasingly popular for use in film, game, and broadcast pipelines. Author Scott Spencer is embedded in the ZBrush community and his movie credits include Harry Potter and The Or

  4. WWC Evidence Review Protocol for Character Education Interventions

    Science.gov (United States)

    What Works Clearinghouse, 2014

    2014-01-01

    Character education is an inclusive concept regarding all aspects of how families, schools, and related social institutions support the positive character development of children and adults. "Character" in this context refers to the moral and ethical qualities of persons as well as the demonstration of those qualities in their emotional…

  5. Character Education of the Most Developed Countries in ASEAN

    Science.gov (United States)

    Istiningsih

    2016-01-01

    Character education into an international issue, especially in developing countries. More specifically in Indonesia, character education is a major issue in the 2012's to the present. What kind of education that may build character? To be able to answer this question, we need a broad and deep research. Research simpler related to character…

  6. Resolving Conflict: Methods Used by TV Characters and Teenage Viewers.

    Science.gov (United States)

    Roloff, Michael E.; Greenberg, Bradley S.

    1979-01-01

    Tested hypotheses that action/adventure characters are perceived by teenagers as likely to engage in antisocial conflict resolution; situation comedy/family drama characters, in prosocial modes. Also tested was hypothesis that, as favorite character's perceived use of a mode increases, so does the viewer's intention to use the same mode. (SW)

  7. Once Upon a Time: A Grimm Approach to Character Education

    Science.gov (United States)

    Bryan, Laura

    2005-01-01

    Many school districts have implemented "packaged" programs designed to teach character education. Millions of dollars have been spent on these programs, yet society continues to produce more "characters" than students "with character." This article describes a shift from the "programmatic" mindset to a solution that is not packaged or purchased.…

  8. The Importance of Character Development: An Interview with Ron Kinnamon.

    Science.gov (United States)

    Kinnamon, Ron

    2003-01-01

    Building good character in today's youth is an adult issue because children learn values from adults. Adults must demonstrate the core values: trustworthiness, respect, responsibility, fairness, caring, and citizenship. Camps have developed expertise in character development and can provide leadership in the community in character education.…

  9. Character Education in Three Schools: Catholic, Quaker and Public

    Science.gov (United States)

    Meidl, Christopher; Meidl, Tynisha

    2013-01-01

    Character education has always played a role in the purpose of schools. Most US states have a statement about character education as a part of the mission of the schools. This research studied how character education was perceived by participants in regards to school mission statements/philosophies, school atmosphere and curriculum in a Catholic…

  10. Picture This Character: Using Imagery To Teach a Japanese Syllabary.

    Science.gov (United States)

    Thompson, Joyce D.; Wakefield, John F.

    This study examined the effectiveness of imagery to teach native English speakers to associate hiragana characters (a Japanese script) with the spoken Japanese syllables that the characters represent. Twenty-one adults in a psychology of learning class for teachers were taught to picture a hiragana character in such a way as to establish an…

  11. Good character at school: positive classroom behavior mediates the link between character strengths and school achievement.

    Science.gov (United States)

    Wagner, Lisa; Ruch, Willibald

    2015-01-01

    Character strengths have been found to be substantially related to children's and adolescents' well-being. Initial evidence suggests that they also matter for school success (e.g., Weber and Ruch, 2012). The present set of two studies aimed at replicating and extending these findings in two different age groups, primary school students (N = 179; mean age = 11.6 years) and secondary school students (N = 199; mean age = 14.4 years). The students completed the VIA-Youth (Values in Action Inventory of Strengths for Youth), a self-report measure of the 24 character strengths in the VIA classification. Their teachers rated the students' positive behavior in the classroom. Additionally, school achievement was assessed: For the primary school students (Study 1), teachers rated the students' overall school achievement and for the secondary school students (Study 2), we used their grades as a measure of school achievement. We found that several character strengths were associated with both positive classroom behavior and school achievement. Across both samples, school achievement was correlated with love of learning, perseverance, zest, gratitude, hope, and perspective. The strongest correlations with positive classroom behavior were found for perseverance, self-regulation, prudence, social intelligence, and hope. For both samples, there were indirect effects of some of the character strengths on school achievement through teacher-rated positive classroom behavior. The converging findings from the two samples support the notion that character strengths contribute to positive classroom behavior, which in turn enhances school achievement. Results are discussed in terms of their implications for future research and for school interventions based on character strengths.

  12. Good character at school: Positive classroom behavior mediates the link between character strengths and school achievement

    Directory of Open Access Journals (Sweden)

    Lisa eWagner

    2015-05-01

    Full Text Available Character strengths have been found to be substantially related to children’s and adolescents’ well-being. Initial evidence suggests that they also matter for school success (e.g., Weber and Ruch, 2012. The present set of two studies aimed at replicating and extending these findings in two different age groups, primary school students (N = 179; mean age = 11.6 years and secondary school students (N = 199; mean age = 14.4 years. The students completed the VIA-Youth, a self-report measure of the 24 character strengths in the VIA classification. Their teachers rated the students’ positive behavior in the classroom. Additionally, school achievement was assessed: For the primary school students (Study 1, teachers rated the students’ overall school achievement and for the secondary school students (Study 2, we used their grades as a measure of school achievement. We found that several character strengths were associated with both positive classroom behavior and school achievement. Across both samples school achievement was correlated with love of learning, perseverance, zest, gratitude, hope, and perspective. The strongest correlations with positive classroom behavior were found for perseverance, self-regulation, prudence, social intelligence, and hope. For both samples, there were indirect effects of most of the character strengths on school achievement through teacher-rated positive classroom behavior. The converging findings from the two samples support the notion that character strengths contribute to positive classroom behavior, which in turn enhances school achievement. Results are discussed in terms of their implications for future research and for school interventions based on character strengths.

  13. Coval: improving alignment quality and variant calling accuracy for next-generation sequencing data.

    Directory of Open Access Journals (Sweden)

    Shunichi Kosugi

    Full Text Available Accurate identification of DNA polymorphisms using next-generation sequencing technology is challenging because of a high rate of sequencing error and incorrect mapping of reads to reference genomes. Currently available short read aligners and DNA variant callers suffer from these problems. We developed the Coval software to improve the quality of short read alignments. Coval is designed to minimize the incidence of spurious alignment of short reads, by filtering mismatched reads that remained in alignments after local realignment and error correction of mismatched reads. The error correction is executed based on the base quality and allele frequency at the non-reference positions for an individual or pooled sample. We demonstrated the utility of Coval by applying it to simulated genomes and experimentally obtained short-read data of rice, nematode, and mouse. Moreover, we found an unexpectedly large number of incorrectly mapped reads in 'targeted' alignments, where the whole genome sequencing reads had been aligned to a local genomic segment, and showed that Coval effectively eliminated such spurious alignments. We conclude that Coval significantly improves the quality of short-read sequence alignments, thereby increasing the calling accuracy of currently available tools for SNP and indel identification. Coval is available at http://sourceforge.net/projects/coval105/.

  14. The covalence effect of energy levels of ZnS:Mn2+

    International Nuclear Information System (INIS)

    Dong-Yang, Li; Mao-Lu, Du; Yi, Huang

    2013-01-01

    The contribution of the different covalence for t 2 and e orbitals must be considered in the investigation of the optical and magnetic properties of the transition metal ion in II–VI and III–V semiconductors. In present paper, two covalent parameters N t and N e associated with t 2 and e orbitals have been adopted to describe the covalence. The energy matrices considering the different covalence for t 2 and e orbitals have been provided for d 5 ions in crystal. These matrices show that the contribution from the Racah parameter A cannot be neglected in calculation of energy-level of d 5 ions in covalent crystal. The calculated results using the matrix show that the energy levels of 4 E and 4 A 1 states split, and the energy-level difference between 4 E and 4 A 1 states increases with increase of the different covalence between t 2 and e orbitals. These energy levels are always degenerate, when the different covalence for t 2 and e orbitals is neglected. By using the energy matrices, the energy-level of ZnS:Mn 2+ has been calculated. The calculated energy levels of ZnS:Mn 2+ are in good agreement with the experiments

  15. Partial knee replacement - slideshow

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/presentations/100225.htm Partial knee replacement - series—Normal anatomy To use the sharing ... A.M. Editorial team. Related MedlinePlus Health Topics Knee Replacement A.D.A.M., Inc. is accredited ...

  16. COVALENT IMMOBILIZATION OF INVERTASE ON EPOXY-ACTIVATED POLYANILINE FILMS

    Directory of Open Access Journals (Sweden)

    Loredana Vacareanu

    2013-08-01

    Full Text Available The growing interest in manufacturing and use of biosensors is their rapid and selective detection of the target analyte. The immobilization of the enzymes, onto the appropriate matrix is the key-step in the construction of biosensing devices, considerably affecting its performance. In this study, new polyaniline bearing epoxy groups was synthesized by electrochemical polymerization reactions, as adherent, green film deposited on electrode surface, and was further used as immobilization matrix for invertase enzyme. The immobilization was carried out by condensation reactions between the amino groups of the enzyme molecules and the epoxy groups of polyaniline film. The covalent attachment was achieved by simple immersing the epoxy-activated polyaniline in acetate buffer solution (10 mM, pH 6.0 containing 2mg/mL invertase, for 24 h at 4 ºC, by continuous stirring. The polyaniline films thus obtained were analyzed before and after the invertase attachment, by using FT-IR spectroscopy and SEM microscopy. The presence of the invertase was evaluated by measuring their activity, using UV-Vis spectroscopy, in the presence of a known amount of sucrose as a substrate. These tests, performed for three times under the same conditions, revealed that even after five washes of the polyaniline /invertase electrode to remove the unbounded enzyme, the enzyme remain attached on the polyaniline film, being able to hydrolyze the sucrose presented in the assay solutions.

  17. Characterising non-covalent interactions with the Cambridge Structural Database.

    Science.gov (United States)

    Lommerse, J P; Taylor, R

    1997-02-01

    This review describes how the CSD can be used to study non-covalent interactions. Several different types of information may be obtained. First, the relative frequencies of various interactions can be studied; for example, we have shown that the terminal oxygen atoms of phosphate groups accept hydrogen bonds far more often than the linkage oxygens. Secondly, information can be obtained about the geometries of nonbonded contacts; for example, hydrogen bonds to P-O groups rarely form along the extension of the P-O bond, whereas short contacts between oxygen and carbon-bound iodine show a strong preference for linear C-I ... O angles. Thirdly, the CSD can be searched for novel interactions which may be exploited in inhibitor design; for example, the I ... O contacts just mentioned, and N-H ... pi hydrogen bonds. Finally, the CSD can suggest synthetic targets for medicinal chemistry; for example, molecules containing delocalised electron deficient groups such as trimethylammonium, pyridinium, thaizolium and dinitrophenyl have a good chance of binding to an active-site tryptophan. Although the CSD contains small-molecule crystal structures, not protein-ligand complexes, there is considerable evidence that the contacts seen in the two types of structures are similar. We have illustrated this a number of times in the present review and additional evidence has been given previously by Klebe. The major advantages of the CSD are its size, diversity and experimental accuracy. For these reasons, it is a useful tool for modellers engaged in rational inhibitor design.

  18. Covalently Bonded Chitosan on Graphene Oxide via Redox Reaction

    Directory of Open Access Journals (Sweden)

    Víctor M. Castaño

    2013-03-01

    Full Text Available Carbon nanostructures have played an important role in creating a new field of materials based on carbon. Chemical modification of carbon nanostructures through grafting has been a successful step to improve dispersion and compatibility in solvents, with biomolecules and polymers to form nanocomposites. In this sense carbohydrates such as chitosan are extremely valuable because their functional groups play an important role in diversifying the applications of carbon nanomaterials. This paper reports the covalent attachment of chitosan onto graphene oxide, taking advantage of this carbohydrate at the nanometric level. Grafting is an innovative route to modify properties of graphene, a two-dimensional nanometric arrangement, which is one of the most novel and promising nanostructures. Chitosan grafting was achieved by redox reaction using different temperature conditions that impact on the morphology and features of graphene oxide sheets. Transmission Electron Microscopy, Fourier Transform Infrared, Raman and Energy Dispersive spectroscopies were used to study the surface of chitosan-grafted-graphene oxide. Results show a successful modification indicated by the functional groups found in the grafted material. Dispersions of chitosan-grafted-graphene oxide samples in water and hexane revealed different behavior due to the chemical groups attached to the graphene oxide sheet.

  19. Selective Covalent Conjugation of Phosphorothioate DNA Oligonucleotides with Streptavidin

    Directory of Open Access Journals (Sweden)

    Christof M. Niemeyer

    2011-08-01

    Full Text Available Protein-DNA conjugates have found numerous applications in the field of diagnostics and nanobiotechnology, however, their intrinsic susceptibility to DNA degradation by nucleases represents a major obstacle for many applications. We here report the selective covalent conjugation of the protein streptavidin (STV with phosphorothioate oligonucleotides (psDNA containing a terminal alkylthiolgroup as the chemically addressable linking unit, using a heterobifunctional NHS-/maleimide crosslinker. The psDNA-STV conjugates were synthesized in about 10% isolated yields. We demonstrate that the terminal alkylthiol group selectively reacts with the maleimide while the backbone sulfur atoms are not engaged in chemical conjugation. The novel psDNA-STV conjugates retain their binding capabilities for both biotinylated macromolecules and the complementary nucleic acid. Moreover, the psDNA-STV conjugate retained its binding capacity for complementary oligomers even after a nuclease digestion step, which effectively degrades deoxyribonucleotide oligomers and thus the binding capability of regular DNA-STV conjugates. The psDNA-STV therefore hold particular promise for applications e.g. in proteome research and novel biosensing devices, where interfering endogenous nucleic acids need to be removed from analytes by nuclease digestion.

  20. Self-Suspended Suspensions of Covalently Grafted Hairy Nanoparticles

    KAUST Repository

    Choudhury, Snehashis

    2015-03-17

    © 2015 American Chemical Society. Dispersions of small particles in liquids have been studied continuously for almost two centuries for their ability to simultaneously advance understanding of physical properties of fluids and their widespread use in applications. In both settings, the suspending (liquid) and suspended (solid) phases are normally distinct and uncoupled on long length and time scales. In this study, we report on the synthesis and physical properties of a novel family of covalently grafted nanoparticles that exist as self-suspended suspensions with high particle loadings. In such suspensions, we find that the grafted polymer chains exhibit unusual multiscale structural transitions and enhanced conformational stability on subnanometer and nanometer length scales. On mesoscopic length scales, the suspensions display exceptional homogeneity and colloidal stability. We attribute this feature to steric repulsions between grafted chains and the space-filling constraint on the tethered chains in the single-component self-suspended materials, which inhibits phase segregation. On macroscopic length scales, the suspensions exist as neat fluids that exhibit soft glassy rheology and, counterintuitively, enhanced elasticity with increasing temperature. This feature is discussed in terms of increased interpenetration of the grafted chains and jamming of the nanoparticles. (Chemical Presented).

  1. Hydrolytic Stability of Boronate Ester-Linked Covalent Organic Frameworks

    KAUST Repository

    Li, Huifang

    2018-01-30

    The stability of covalent organic frameworks (COFs) is essential to their applications. However, the common boronate ester-linked COFs are susceptible to attack by nucleophiles (such as water molecules) at the electron-deficient boron sites. To provide an understanding of the hydrolytic stability of the representative boronate ester-linked COF-5 and of the associated hydrolysis mechanisms, density functional theory (DFT) calculations were performed to characterize the hydrolysis reactions of the molecule formed by the condensation of 1,4-phenylenebis(boronic acid) (PBBA) and 2,3,6,7,10,11-hexahydroxytriphenylene (HHTP) monomers; two cases were considered, one dealing with the freestanding molecule and the other with the molecule interacting with COF layers. It was found that the boronate ester (B–O) bond dissociation, which requires one H2O molecule, has a relatively high energy barrier of 22.3 kcal mol−1. However, the presence of an additional H2O molecule significantly accelerates hydrolysis by reducing the energy barrier by a factor of 3. Importantly, the hydrolysis of boronate ester bonds situated in a COF environment follows reaction pathways that are different and have increased energy barriers. These results point to an enhanced hydrolytic stability of COF-5 crystals.

  2. Covalently functionalized graphene sheets with biocompatible natural amino acids

    International Nuclear Information System (INIS)

    Mallakpour, Shadpour; Abdolmaleki, Amir; Borandeh, Sedigheh

    2014-01-01

    Graphene sheets were covalently functionalized with aromatic–aliphatic amino acids (phenylalanine and tyrosine) and aliphatic amino acids (alanine, isoleucine, leucine, methionine and valine) by simple and green procedure. For this aim, at first natural graphite was converted into graphene oxide (GO) through strong oxidation procedure; then, based on the surface-exposed epoxy and carboxylic acid groups in GO solid, its surface modification with naturally occurring amino acids, occurred easily throughout the corresponding nucleophilic substitution and condensation reactions. Amino acid functionalized graphene demonstrates stable dispersion in water and common organic solvents. Fourier transform infrared, Raman and X-ray photoelectron spectroscopies, X-ray diffraction, field emission scanning electron microscopy and transmission electron microscopy were used to investigate the nanostructures and properties of prepared materials. Each amino acid has different considerable effects on the structure and morphology of the pure graphite, from increasing the layer spacing to layer scrolling, based on their structures, functional groups and chain length. In addition, therogravimetric analysis was used for demonstrating a successful grafting of amino acid molecules to the surface of graphene.

  3. Unsynchronized resonance of covalent bonds in the superconducting state

    International Nuclear Information System (INIS)

    Costa, Marconi B.S.; Bastos, Cristiano C.; Pavao, Antonio C.

    2012-01-01

    Daft calculations performed on different cluster models of cuprates (LaBa 2 Cu 3 O 6.7 , La 1.85 Sr 0.15 CuO 4 , YBa 2 Cu 3 O 7 , TlBa 2 Ca 2 Cu 3 O 8.78 , HgBa 2 Ca 2 Cu 3 O 8.27 ), metallic systems (Nb 3 Ge, MgB 2 ) and the pnictide LaO 0.92 F 0.08 FeAs made evident the occurrence of un synchronized resonance of covalent bonds in the superconducting state, as predicted by Paling's resonating valence bond Rb) theory. For cuprates, the un synchronized resonance involves electron transfer between Cu atoms accompanied by a decrease in the charge of the La, Sr, Y and Ca atoms. For MgB 2 , electron transfer occurs in the Mg layer, while the B layer behaves as charge reservoir. For Nb 3 Ge, unsynchronized resonance occurs among the Ge atoms, which should be responsible for charge transfer. For LaO 0.92 F 0.08 FeAs, the results suggest that both La-O and Fe-As layers are involved in the mechanism of superconductivity. The identification of unsynchronized resonances in these systems provides evidence which supports RVB as a suitable theory for high-temperature superconductivity (high-TC). (author)

  4. Extending density functional embedding theory for covalently bonded systems.

    Science.gov (United States)

    Yu, Kuang; Carter, Emily A

    2017-12-19

    Quantum embedding theory aims to provide an efficient solution to obtain accurate electronic energies for systems too large for full-scale, high-level quantum calculations. It adopts a hierarchical approach that divides the total system into a small embedded region and a larger environment, using different levels of theory to describe each part. Previously, we developed a density-based quantum embedding theory called density functional embedding theory (DFET), which achieved considerable success in metals and semiconductors. In this work, we extend DFET into a density-matrix-based nonlocal form, enabling DFET to study the stronger quantum couplings between covalently bonded subsystems. We name this theory density-matrix functional embedding theory (DMFET), and we demonstrate its performance in several test examples that resemble various real applications in both chemistry and biochemistry. DMFET gives excellent results in all cases tested thus far, including predicting isomerization energies, proton transfer energies, and highest occupied molecular orbital-lowest unoccupied molecular orbital gaps for local chromophores. Here, we show that DMFET systematically improves the quality of the results compared with the widely used state-of-the-art methods, such as the simple capped cluster model or the widely used ONIOM method.

  5. Beginning partial differential equations

    CERN Document Server

    O'Neil, Peter V

    2014-01-01

    A broad introduction to PDEs with an emphasis on specialized topics and applications occurring in a variety of fields Featuring a thoroughly revised presentation of topics, Beginning Partial Differential Equations, Third Edition provides a challenging, yet accessible,combination of techniques, applications, and introductory theory on the subjectof partial differential equations. The new edition offers nonstandard coverageon material including Burger's equation, the telegraph equation, damped wavemotion, and the use of characteristics to solve nonhomogeneous problems. The Third Edition is or

  6. Modeling the Semiotic Structure of Player-Characters

    DEFF Research Database (Denmark)

    Vella, Daniel

    2014-01-01

    When game studies has tackled the player-character, it has tended to do so by means of an opposition to the notion of the avatar, with the result that the ontological and semiotic nature of the character in itself has not been given due attention. This paper draws on understandings of character...... from the fields of narratology and literary theory to highlight the double-layered ontology of character as both a possible individual and as a semiotic construction. Uri Margolin’s narratological model of character signification is used as the basis for developing a semiotic-structural model...

  7. Measuring multi-configurational character by orbital entanglement

    Science.gov (United States)

    Stein, Christopher J.; Reiher, Markus

    2017-09-01

    One of the most critical tasks at the very beginning of a quantum chemical investigation is the choice of either a multi- or single-configurational method. Naturally, many proposals exist to define a suitable diagnostic of the multi-configurational character for various types of wave functions in order to assist this crucial decision. Here, we present a new orbital-entanglement-based multi-configurational diagnostic termed Zs(1). The correspondence of orbital entanglement and static (or non-dynamic) electron correlation permits the definition of such a diagnostic. We chose our diagnostic to meet important requirements such as well-defined limits for pure single-configurational and multi-configurational wave functions. The Zs(1) diagnostic can be evaluated from a partially converged, but qualitatively correct, and therefore inexpensive density matrix renormalisation group wave function as in our recently presented automated active orbital selection protocol. Its robustness and the fact that it can be evaluated at low cost make this diagnostic a practical tool for routine applications.

  8. READING LITERATURE, TAKING PHILOSOPHICAL IDEAS, AND OBTAINING CHARACTERS

    Directory of Open Access Journals (Sweden)

    Siti Maisaroh

    2017-05-01

    Full Text Available This study aims to describe the philosophical ideas and characters containing in trilogy of 'RaraMendut's' novel by YB Mangunwijaya. The method used is the knowledge archeology of Michel Foucault. The research proves that the philosophical ideas as follows: 1 wife's faithfulness contains characters of wife’s strong determination and true faithfulness sense; 2 The women seizing fate's  contains the character of high struggle spirit;3 women as a glory’s symbol contains character of self-actualization ability; 4 women and a country's defense contains a character of clever to take on the role / responsive; 5 women and their benefits contains the character as a source of love and life spirit; 6 women as good mothers contains the character of conciliatory, reassuring, joyful, sincere, and full of love; 7 the anxiety to old age contains the character of religious and strong self-awareness; 8 the glory contains the character of the glory of battle with themselves; 9 the child's nature contains the character of belief in the skill/ creativity of children and believe to God the Evolver; And 10 the essence of wisdom and usefulness of life contain  the characters of uniting the scattered things, receiving and embracing sincerely things bad/ broken/ waste, understanding and forgiving, voice sincerity and excitement, not easy to complain.

  9. Handwritten Javanese Character Recognition Using Several Artificial Neural Network Methods

    Directory of Open Access Journals (Sweden)

    Gregorius Satia Budhi

    2015-07-01

    Full Text Available Javanese characters are traditional characters that are used to write the Javanese language. The Javanese language is a language used by many people on the island of Java, Indonesia. The use of Javanese characters is diminishing more and more because of the difficulty of studying the Javanese characters themselves. The Javanese character set consists of basic characters, numbers, complementary characters, and so on. In this research we have developed a system to recognize Javanese characters. Input for the system is a digital image containing several handwritten Javanese characters. Preprocessing and segmentation are performed on the input image to get each character. For each character, feature extraction is done using the ICZ-ZCZ method. The output from feature extraction will become input for an artificial neural network. We used several artificial neural networks, namely a bidirectional associative memory network, a counterpropagation network, an evolutionary network, a backpropagation network, and a backpropagation network combined with chi2. From the experimental results it can be seen that the combination of chi2 and backpropagation achieved better recognition accuracy than the other methods.

  10. Character education in perspective of chemistry pre-service teacher

    Science.gov (United States)

    Merdekawati, Krisna

    2017-12-01

    As one of the pre-service teacher education programs, Chemistry Education Department Islamic University of Indonesia (UII) is committed to providing quality education. It is an education that can produce competent and characteristic chemistry pre-service teacher. The focus of research is to describe the perception of students as a potential teacher of chemistry on character education and achievement of character education. The research instruments include questionnaires and observation sheets. Research data show that students have understood the importance of character education and committed to organizing character education later in schools. Students have understood the ways in which character education can be used. The students stated that Chemistry Education Department has tried to equip students with character education. The observation result shows that students generally have character as a pre-service teacher.

  11. On the information content of discrete phylogenetic characters.

    Science.gov (United States)

    Bordewich, Magnus; Deutschmann, Ina Maria; Fischer, Mareike; Kasbohm, Elisa; Semple, Charles; Steel, Mike

    2017-12-16

    Phylogenetic inference aims to reconstruct the evolutionary relationships of different species based on genetic (or other) data. Discrete characters are a particular type of data, which contain information on how the species should be grouped together. However, it has long been known that some characters contain more information than others. For instance, a character that assigns the same state to each species groups all of them together and so provides no insight into the relationships of the species considered. At the other extreme, a character that assigns a different state to each species also conveys no phylogenetic signal. In this manuscript, we study a natural combinatorial measure of the information content of an individual character and analyse properties of characters that provide the maximum phylogenetic information, particularly, the number of states such a character uses and how the different states have to be distributed among the species or taxa of the phylogenetic tree.

  12. Boolean logic and character state identity: pitfalls of character coding in metazoan cladistics

    NARCIS (Netherlands)

    Jenner, Ronald A.

    2002-01-01

    A critical study of the morphological data sets used for the most recent analyses of metazoan cladistics exposes a rather cavalier attitude towards character coding. Binary absence/presence coding is ubiquitous, but without any explicit justification. This uncompromising application of Boolean logic

  13. Explaining the role of character development in the evaluation of morally ambiguous characters in entertainment media

    NARCIS (Netherlands)

    Kleemans, M.; Eden, A.; Daalmans, S.; Ommen, M.E. van; Weijers, G.W.M.

    2017-01-01

    The current project aims at better understanding how narrative characteristics in stories function in the liking, moral evaluation, and enjoyment of narratives featuring morally ambiguous characters (MACs). Shafer and Raney (2012) found that viewers differently enjoyed a heroic versus MAC-centered

  14. Covalent bonding and band-gap formation in ternary transition-metal di-aluminides: Al4MnCo and related compounds

    International Nuclear Information System (INIS)

    Krajci, M.; Hafner, J.

    2002-01-01

    In this paper we extend our previous study of the electronic structure of and bonding mechanism in transition-metal (TM) di-aluminides to ternary systems. We have studied the character of the bonding in Al 4 MnCo and related TM di-aluminides in the C11 b (MoSi 2 ) and C54 (TiSi 2 ) crystal structures. A peculiar feature of the electronic structure of these TM di-aluminides is the existence of a semiconducting gap at the Fermi level. In our previous work we predicted a gap in Al 2 TM compounds where the TM atoms have eight valence electrons. Here we demonstrate that the semiconducting gap does not disappear if the TM sites are occupied by two different TMs, provided that the electron-per-atom ratio is conserved. Such a replacement substantially increases the class of possibly semiconducting TM di-aluminides. Substitution for 3d TMs of 4d or 5d TMs enhances the width of the gap. From the analysis of the charge density distribution and the crystal orbital overlap population, we conclude that the bonding between atoms has dominantly covalent character. This is confirmed not only by the enhanced charge density halfway between atoms, but also by the clear bonding-antibonding splitting of the electronic states. If the gaps between split states that correspond to all bonding configurations in the crystal have a common overlap at the Fermi level, the intermetallic compound becomes a semiconductor. However, the results of the total-energy calculations suggest that the existence of a band gap does not necessarily imply a stable structure. Strong covalent bonds can exist also in Al-TM structures where no band gap is observed. (author)

  15. Stereotype or success? Prime-time television's portrayals of gay male, lesbian, and bisexual characters.

    Science.gov (United States)

    Raley, Amber B; Lucas, Jennifer L

    2006-01-01

    The current content analysis of prime-time network television during the fall of 2001 seeks to identify the representation of Gay male, Lesbian, and Bisexual characters in shows known to have one reoccurring homosexual character based on the theories of Clark and Berry. Clark (1969) established four stages of media representation for minority groups: non-representation, ridicule, regulation, and respect. The findings of the study support the premise that Gay males and Lesbians have passed Clark's stage of non-representation and have progressed into the stage of ridicule and some are moving into the stages of regulation and respect. Berry (1980) devised three periods based on the television portrayal of Blacks: The Stereotypic Age, The New Awareness, and Stabilization. Results were mixed, with only a partial support of the hypothesis that Gay males and Lesbians had advanced beyond The Stereotypic Age.

  16. Surface passivation for tight-binding calculations of covalent solids

    International Nuclear Information System (INIS)

    Bernstein, N

    2007-01-01

    Simulation of a cluster representing a finite portion of a larger covalently bonded system requires the passivation of the cluster surface. We compute the effects of an explicit hybrid orbital passivation (EHOP) on the atomic structure in a model bulk, three-dimensional, narrow gap semiconductor, which is very different from the wide gap, quasi-one-dimensional organic molecules where most passivation schemes have been studied in detail. The EHOP approach is directly applicable to minimal atomic orbital basis methods such as tight-binding. Each broken bond is passivated by a hybrid created from an explicitly expressed linear combination of basis orbitals, chosen to represent the contribution of the missing neighbour, e.g. a sp 3 hybrid for a single bond. The method is tested by computing the forces on atoms near a point defect as a function of cluster geometry. We show that, compared to alternatives such as pseudo-hydrogen passivation, the force on an atom converges to the correct bulk limit more quickly as a function of cluster radius, and that the force is more stable with respect to perturbations in the position of the cluster centre. The EHOP method also obviates the need for parameterizing the interactions between the system atoms and the passivating atoms. The method is useful for cluster calculations of non-periodic defects in large systems and for hybrid schemes that simulate large systems by treating finite regions with a quantum-mechanical model, coupled to an interatomic potential description of the rest of the system

  17. Covalent dimerization of ribulose bisphosphate carboxylase subunits by UV radiation

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, R.M.B. [Universidade Tecnica, Lisbon (Portugal). Inst. Superior de Agronomia]|[Universidade Nova de Lisboa, Oeiras (Portugal). Instituto de Tecnologia Quimica e Biologica; Franco, E.; Teixeira, A.R.N. [Universidade Tecnica, Lisbon (Portugal). Inst. Superior de Agronomia

    1996-08-15

    The effect of UV radiation (UV-A, UV-B and UV-C) on ribulose bisphosphate carboxylase from a variety of plant species was examined. The exposition of plant leaves or the pure enzyme to UV radiation produced a UV-dependent accumulation of a 65 kDa polypeptide (P65). Different approaches were utilized to elucidate the origin and structure of P65: electrophoretic and fluorographic analyses of {sup 35}S-labelled ribulose biphosphate carboxylase exposed to UV radiation and immunological experiments using antibodies specific for P65, for the large and small subunits of ribulose biphosphate carboxylase and for high-molecular-mass aggregates of the enzyme. These studies revealed that P65 is a dimer, formed by the covalent, non-disulphide linkage of one small subunit with one large subunit of ribulose biphosphate carboxylase. For short periods of time (<1 h), the amount of P65 formed increased with the duration of the exposure to the UV radiation and with the energy of the radiation applied. Prolonged exposure to UV radiation (1-6 h) resulted in the formation of high-molecular-mass aggregates of ribulose biphosphate carboxylase. Formation of P65 was shown to depend on the native state of the protein, was stimulated by inhibitors of enzyme activity, and was inhibited by activators of enzyme activity. A UV-independent accumulation of P65 was also achieved by the in vitro incubation of plant crude extracts. However, the UV-dependent and the UV-independent formation of P65 seemed to occur by distinct molecular mechanisms. The UV-dependent accumulation of P65 was immunologically detected in all species examined, including Lemna minor, Arum italicum, Brassica oleracea, Triticum aestivum, Zea mays, Pisum sativum and Phaseolus vulgaris, suggesting that it may constitute a universal response to UV radiation, common to all photosynthetic tissues. (Author).

  18. Covalent dimerization of ribulose bisphosphate carboxylase subunits by UV radiation

    International Nuclear Information System (INIS)

    Ferreira, R.M.B.; Universidade Nova de Lisboa, Oeiras; Franco, E.; Teixeira, A.R.N.

    1996-01-01

    The effect of UV radiation (UV-A, UV-B and UV-C) on ribulose bisphosphate carboxylase from a variety of plant species was examined. The exposition of plant leaves or the pure enzyme to UV radiation produced a UV-dependent accumulation of a 65 kDa polypeptide (P65). Different approaches were utilized to elucidate the origin and structure of P65: electrophoretic and fluorographic analyses of 35 S-labelled ribulose biphosphate carboxylase exposed to UV radiation and immunological experiments using antibodies specific for P65, for the large and small subunits of ribulose biphosphate carboxylase and for high-molecular-mass aggregates of the enzyme. These studies revealed that P65 is a dimer, formed by the covalent, non-disulphide linkage of one small subunit with one large subunit of ribulose biphosphate carboxylase. For short periods of time (<1 h), the amount of P65 formed increased with the duration of the exposure to the UV radiation and with the energy of the radiation applied. Prolonged exposure to UV radiation (1-6 h) resulted in the formation of high-molecular-mass aggregates of ribulose biphosphate carboxylase. Formation of P65 was shown to depend on the native state of the protein, was stimulated by inhibitors of enzyme activity, and was inhibited by activators of enzyme activity. A UV-independent accumulation of P65 was also achieved by the in vitro incubation of plant crude extracts. However, the UV-dependent and the UV-independent formation of P65 seemed to occur by distinct molecular mechanisms. The UV-dependent accumulation of P65 was immunologically detected in all species examined, including Lemna minor, Arum italicum, Brassica oleracea, Triticum aestivum, Zea mays, Pisum sativum and Phaseolus vulgaris, suggesting that it may constitute a universal response to UV radiation, common to all photosynthetic tissues. (Author)

  19. Adaptive polymeric nanomaterials utilizing reversible covalent and hydrogen bonding

    Science.gov (United States)

    Neikirk, Colin

    Adaptive materials based on stimuli responsive and reversible bonding moieties are a rapidly developing area of materials research. Advances in supramolecular chemistry are now being adapted to novel molecular architectures including supramolecular polymers to allow small, reversible changes in molecular and nanoscale structure to affect large changes in macroscale properties. Meanwhile, dynamic covalent chemistry provides a complementary approach that will also play a role in the development of smart adaptive materials. In this thesis, we present several advances to the field of adaptive materials and also provide relevant insight to the areas of polymer nanocomposites and polymer nanoparticles. First, we have utilized the innate molecular recognition and binding capabilities of the quadruple hydrogen bonding group ureidopyrimidinone (UPy) to prepare supramolecular polymer nanocomposites based on supramolecular poly(caprolactone) which show improved mechanical properties, but also an increase in particle aggregation with nanoparticle UPy functionalization. We also present further insight into the relative effects of filler-filler, filler-matrix, and matrix-matrix interactions using a UPy side-chain functional poly(butyl acrylate). These nanocomposites have markedly different behavior depending on the amount of UPy sidechain functionality. Meanwhile, our investigations of reversible photo-response showed that coumarin functionality in polymer nanoparticles not only facilitates light mediated aggregation/dissociation behavior, but also provides a substantial overall reduction in particle size and improvement in nanoparticle stability for particles prepared by Flash NanoPrecipitation. Finally, we have combined these stimuli responsive motifs as a starting point for the development of multiresponsive adaptive materials. The synthesis of a library of multifunctional materials has provided a strong base for future research in this area, although our initial

  20. Braille character discrimination in blindfolded human subjects.

    Science.gov (United States)

    Kauffman, Thomas; Théoret, Hugo; Pascual-Leone, Alvaro

    2002-04-16

    Visual deprivation may lead to enhanced performance in other sensory modalities. Whether this is the case in the tactile modality is controversial and may depend upon specific training and experience. We compared the performance of sighted subjects on a Braille character discrimination task to that of normal individuals blindfolded for a period of five days. Some participants in each group (blindfolded and sighted) received intensive Braille training to offset the effects of experience. Blindfolded subjects performed better than sighted subjects in the Braille discrimination task, irrespective of tactile training. For the left index finger, which had not been used in the formal Braille classes, blindfolding had no effect on performance while subjects who underwent tactile training outperformed non-stimulated participants. These results suggest that visual deprivation speeds up Braille learning and may be associated with behaviorally relevant neuroplastic changes.

  1. Covalent modification of graphene and graphite using diazonium chemistry: tunable grafting and nanomanipulation.

    Science.gov (United States)

    Greenwood, John; Phan, Thanh Hai; Fujita, Yasuhiko; Li, Zhi; Ivasenko, Oleksandr; Vanderlinden, Willem; Van Gorp, Hans; Frederickx, Wout; Lu, Gang; Tahara, Kazukuni; Tobe, Yoshito; Uji-I, Hiroshi; Mertens, Stijn F L; De Feyter, Steven

    2015-05-26

    We shine light on the covalent modification of graphite and graphene substrates using diazonium chemistry under ambient conditions. We report on the nature of the chemical modification of these graphitic substrates, the relation between molecular structure and film morphology, and the impact of the covalent modification on the properties of the substrates, as revealed by local microscopy and spectroscopy techniques and electrochemistry. By careful selection of the reagents and optimizing reaction conditions, a high density of covalently grafted molecules is obtained, a result that is demonstrated in an unprecedented way by scanning tunneling microscopy (STM) under ambient conditions. With nanomanipulation, i.e., nanoshaving using STM, surface structuring and functionalization at the nanoscale is achieved. This manipulation leads to the removal of the covalently anchored molecules, regenerating pristine sp(2) hybridized graphene or graphite patches, as proven by space-resolved Raman microscopy and molecular self-assembly studies.

  2. Covalent organic polymer functionalization of activated carbon surfaces through acyl chloride for environmental clean-up

    DEFF Research Database (Denmark)

    Mines, Paul D.; Thirion, Damien; Uthuppu, Basil

    2017-01-01

    Nanoporous networks of covalent organic polymers (COPs) are successfully grafted on the surfaces of activated carbons, through a series of surface modification techniques, including acyl chloride formation by thionyl chloride. Hybrid composites of activated carbon functionalized with COPs exhibit...

  3. Use of Functionalized Carbon Nanotubes for Covalent Attachment of Nanotubes to Silicon

    Science.gov (United States)

    Tour, James M.; Dyke, Christopher A.; Maya, Francisco; Stewart, Michael P.; Chen, Bo; Flatt, Austen K.

    2012-01-01

    The purpose of the invention is to covalently attach functionalized carbon nanotubes to silicon. This step allows for the introduction of carbon nanotubes onto all manner of silicon surfaces, and thereby introduction of carbon nano - tubes covalently into silicon-based devices, onto silicon particles, and onto silicon surfaces. Single-walled carbon nanotubes (SWNTs) dispersed as individuals in surfactant were functionalized. The nano - tube was first treated with 4-t-butylbenzenediazonium tetrafluoroborate to give increased solubility to the carbon nanotube; the second group attached to the sidewall of the nanotube has a silyl-protected terminal alkyne that is de-protected in situ. This gives a soluble carbon nanotube that has functional groups appended to the sidewall that can be attached covalently to silicon. This reaction was monitored by UV/vis/NJR to assure direct covalent functionalization.

  4. Construction and repair of highly ordered 2D covalent networks by chemical equilibrium regulation.

    Science.gov (United States)

    Guan, Cui-Zhong; Wang, Dong; Wan, Li-Jun

    2012-03-21

    The construction of well-ordered 2D covalent networks via the dehydration of di-borate aromatic molecules was successfully realized through introducing a small amount of water into a closed reaction system to regulate the chemical equilibrium.

  5. Nucleation and Growth of Covalent Organic Frameworks from Solution: The Example of COF-5

    KAUST Repository

    Li, Haoyuan; Chavez, Anton D.; Li, Huifang; Li, Hong; Dichtel, William R.; Bredas, Jean-Luc

    2017-01-01

    The preparation of two-dimensional covalent organic frameworks (2D COFs) with large crystalline domains and controlled morphology is necessary for realizing the full potential of their atomically precise structures and uniform, tailorable porosity

  6. Local Electronic Structure of a Single-Layer Porphyrin-Containing Covalent Organic Framework

    KAUST Repository

    Chen, Chen; Joshi, Trinity; Li, Huifang; Chavez, Anton D.; Pedramrazi, Zahra; Liu, Pei-Nian; Li, Hong; Dichtel, William R.; Bredas, Jean-Luc; Crommie, Michael F.

    2017-01-01

    We have characterized the local electronic structure of a porphyrin-containing single-layer covalent organic framework (COF) exhibiting a square lattice. The COF monolayer was obtained by the deposition of 2,5-dimethoxybenzene-1,4-dicarboxaldehyde

  7. Partial differential equations

    CERN Document Server

    Evans, Lawrence C

    2010-01-01

    This text gives a comprehensive survey of modern techniques in the theoretical study of partial differential equations (PDEs) with particular emphasis on nonlinear equations. The exposition is divided into three parts: representation formulas for solutions; theory for linear partial differential equations; and theory for nonlinear partial differential equations. Included are complete treatments of the method of characteristics; energy methods within Sobolev spaces; regularity for second-order elliptic, parabolic, and hyperbolic equations; maximum principles; the multidimensional calculus of variations; viscosity solutions of Hamilton-Jacobi equations; shock waves and entropy criteria for conservation laws; and, much more.The author summarizes the relevant mathematics required to understand current research in PDEs, especially nonlinear PDEs. While he has reworked and simplified much of the classical theory (particularly the method of characteristics), he primarily emphasizes the modern interplay between funct...

  8. Covalent Crosslinking of Porous Poly(Ionic Liquid) Membrane via a Triazine Network

    OpenAIRE

    Täuber, Karoline; Dani, Alessandro; Yuan, Jiayin

    2017-01-01

    Porous poly(ionic liquid) membranes that were prepared via electrostatic cross-linking were subsequently covalently cross-linked via formation of a 1,3,5-triazine network. The additional covalent cross-links do not affect the pore size and pore size distribution of the membranes and stabilize them towards salt solutions of high ionic strength, enabling the membranes to work in a broader environmental window.

  9. The Chemistry and Biochemistry of Heme c: Functional Bases for Covalent Attachment

    OpenAIRE

    Bowman, Sarah E. J.; Bren, Kara L.

    2008-01-01

    A discussion of the literature concerning the synthesis, function, and activity of heme c-containing proteins is presented. Comparison of the properties of heme c, which is covalently bound to protein, is made to heme b, which is bound noncovalently. A question of interest is why nature uses biochemically expensive heme c in many proteins when its properties are expected to be similar to heme b. Considering the effects of covalent heme attachment on heme conformation and on the proximal histi...

  10. Tissue Plasminogen Activator Binding to Superparamagnetic Iron Oxide Nanoparticle—Covalent Versus Adsorptive Approach

    Science.gov (United States)

    Friedrich, Ralf P.; Zaloga, Jan; Schreiber, Eveline; Tóth, Ildikó Y.; Tombácz, Etelka; Lyer, Stefan; Alexiou, Christoph

    2016-06-01

    Functionalized superparamagnetic iron oxide nanoparticles are frequently used to develop vehicles for drug delivery, hyperthermia, and photodynamic therapy and as tools used for magnetic separation and purification of proteins or for biomolecular imaging. Depending on the application, there are various possible covalent and non-covalent approaches for the functionalization of particles, each of them shows different advantages and disadvantages for drug release and activity at the desired location.

  11. Contribution of the covalent and the Van der Waals force to the nuclear binding

    International Nuclear Information System (INIS)

    Rosina, M.; Povh, B.

    1994-01-01

    The contribution of the covalent and the Van der Waals force to the nuclear binding is estimated in a simplified model for medium distance of about 1 fm. It is shown how colour effects suppress these two forces as compared to the case of the forces between atoms. The covalent and the Van der Waals force represent a minor though noticeable component of the nuclear force. (orig.)

  12. Covalent modification of serum transferrin with phospholipid and incorporation into liposomal membranes

    DEFF Research Database (Denmark)

    Afzelius, P; Demant, E J; Hansen, Gert Helge

    1989-01-01

    A method is described for incorporation of water-soluble proteins into liposomal membranes using covalent protein-phospholipid conjugates in detergent solution. A disulfide derivative of phosphatidylethanolamine containing a reactive N-hydroxysuccinimide ester group is synthesized, and the deriva......A method is described for incorporation of water-soluble proteins into liposomal membranes using covalent protein-phospholipid conjugates in detergent solution. A disulfide derivative of phosphatidylethanolamine containing a reactive N-hydroxysuccinimide ester group is synthesized...

  13. Optimization of partial search

    International Nuclear Information System (INIS)

    Korepin, Vladimir E

    2005-01-01

    A quantum Grover search algorithm can find a target item in a database faster than any classical algorithm. One can trade accuracy for speed and find a part of the database (a block) containing the target item even faster; this is partial search. A partial search algorithm was recently suggested by Grover and Radhakrishnan. Here we optimize it. Efficiency of the search algorithm is measured by the number of queries to the oracle. The author suggests a new version of the Grover-Radhakrishnan algorithm which uses a minimal number of such queries. The algorithm can run on the same hardware that is used for the usual Grover algorithm. (letter to the editor)

  14. Drawing and Recognizing Chinese Characters with Recurrent Neural Network.

    Science.gov (United States)

    Zhang, Xu-Yao; Yin, Fei; Zhang, Yan-Ming; Liu, Cheng-Lin; Bengio, Yoshua

    2018-04-01

    Recent deep learning based approaches have achieved great success on handwriting recognition. Chinese characters are among the most widely adopted writing systems in the world. Previous research has mainly focused on recognizing handwritten Chinese characters. However, recognition is only one aspect for understanding a language, another challenging and interesting task is to teach a machine to automatically write (pictographic) Chinese characters. In this paper, we propose a framework by using the recurrent neural network (RNN) as both a discriminative model for recognizing Chinese characters and a generative model for drawing (generating) Chinese characters. To recognize Chinese characters, previous methods usually adopt the convolutional neural network (CNN) models which require transforming the online handwriting trajectory into image-like representations. Instead, our RNN based approach is an end-to-end system which directly deals with the sequential structure and does not require any domain-specific knowledge. With the RNN system (combining an LSTM and GRU), state-of-the-art performance can be achieved on the ICDAR-2013 competition database. Furthermore, under the RNN framework, a conditional generative model with character embedding is proposed for automatically drawing recognizable Chinese characters. The generated characters (in vector format) are human-readable and also can be recognized by the discriminative RNN model with high accuracy. Experimental results verify the effectiveness of using RNNs as both generative and discriminative models for the tasks of drawing and recognizing Chinese characters.

  15. The influence of media characters on children's food choices.

    Science.gov (United States)

    Kotler, Jennifer A; Schiffman, Jennifer M; Hanson, Katherine G

    2012-01-01

    Two experiments were conducted to assess the role of media characters in influencing children's food choices; the first focused on children's self-reported preference, whereas the second focused on actual choice. The results of the experiments suggest that popular characters can make a difference in encouraging children to select one food over another. In the first experiment, children were more likely to indicate a preference for one food over another when one was associated with characters that they liked and with whom they were familiar. This effect was particularly strong when a sugary or salty snack branded by a favored character was competing with a healthier option branded by an unknown character or no character. Alternatively, when children were asked to choose between a healthy food and a sugary or salty snack, branding of the healthy food with a favored character did not significantly change appeal of that healthy snack. However, when foods within the same category (i.e., 2 vegetables, 2 fruits, or 2 grains) were asked to compete against each other, character branding strongly influenced children's food choice. Findings from the second experiment suggest that children are more willing to try more pieces of a healthy food if a favored character, in comparison with an unknown character, is promoting that food.

  16. THE CHARACTER ANALYSIS OF GLEN HANSARD IN ONCE FILM

    Directory of Open Access Journals (Sweden)

    Nani Rosnani Thamrin

    2013-12-01

    Full Text Available This paper analyzed the characterization of talented actor named Glen Hansard in Once film. This study employed a descriptive qualitative research design based on theories of Rahardjo (1985, Robert (1965, and Card (1988. Primary data sources were whole Once scenes film directed by John Carney which had low-budgeting production with two stars, Glen Hansard and Irglova, while secondary data sources were collected from the articles related to this study. This research mainly investigated two aspects involved two character analyses of the main actor, Hansard. The first one was the construction of Hansard’s characters and the second one was the effect between his character and another actors’ character. The study showed that Hansard’s characters were constructed by five factors: from what the character did and said, what the other characters said about him, how the appearance and its milieu were, influencing one and another.The study also found that he had struggle, visionary, ambitious, introvert, sensitive, straightforward and curious characters, but more characters that showed strong characters of his were struggle, visionary and ambitious, because the scenes reflected them more.

  17. Tailorable thiolated trimethyl chitosans for covalently stabilized nanoparticles.

    Science.gov (United States)

    Verheul, Rolf J; van der Wal, Steffen; Hennink, Wim E

    2010-08-09

    A novel four-step method is presented to synthesize partially thiolated trimethylated chitosan (TMC) with a tailorable degree of quaternization and thiolation. First, chitosan was partially N-carboxylated with glyoxylic acid and sodium borohydride. Next, the remaining amines were quantitatively dimethylated with formaldehyde and sodium borohydride and then quaternized with iodomethane in NMP. Subsequently, these partially carboxylated TMCs dissolved in water were reacted with cystamine at pH 5.5 using EDC as coupling agent. After addition of DTT and dialysis, thiolated TMCs were obtained, varying in degree of quaternization (25-54%) and degree of thiolation (5-7%), as determined with (1)H NMR and Ellman's assay. Gel permeation chromatography with light scattering detection indicated limited intermolecular cross-linking. All thiolated TMCs showed rapid oxidation to yield disulfide cross-linked TMC at pH 7.4, while the thiolated polymers were rather stable at pH 4.0. When Calu-3 cells were used, XTT and LDH cell viability tests showed a slight reduction in cytotoxicity for thiolated TMCs as compared to the nonthiolated polymers with similar DQs. Positively charged nanoparticles loaded with fluorescently labeled ovalbumin were made from thiolated TMCs and thiolated hyaluronic acid. The stability of these particles was confirmed in 0.8 M NaCl, in contrast to particles made from nonthiolated polymers that dissociated under these conditions, demonstrating that the particles were held together by intermolecular disulfide bonds.

  18. The covalent effect on the energy levels of d3 ions in tetragonal compounds

    International Nuclear Information System (INIS)

    Li, Dong-Yang; Du, Mao-Lu

    2015-01-01

    For d 3 ions in covalent compounds with tetragonal symmetry, this paper presents a complete energy matrix, in which the different covalence of t 2 and e orbitals is considered not only in the electrostatic repulsions part of energy matrix elements but also in the crystal-field potential part of energy matrix elements. With taking and no taking the crystal field parameter B 00 0 into account, the effect of covalence on the energy levels of d 3 ions system were investigated, respectively. The investigation shows that it is very necessary for considering the different covalence of t 2 and e orbitals in both electrostatic repulsions part and crystal-field potential part when the optical properties of d 3 ions in strong covalent compounds with tetragonal symmetry is investigated. On the other hand, the crystal field parameter B 00 0 has a significant effect on the energy levels, and should be considered in investigations of d 3 ions in strong covalent compounds with tetragonal symmetry. Application to calculating the energy levels for Co 2+ in CdGa 2 Se 4 , the calculated results are in agreement with the experiment data

  19. Non-covalently functionalized carbon nanostructures for synthesizing carbon-based hybrid nanomaterials.

    Science.gov (United States)

    Li, Haiqing; Song, Sing I; Song, Ga Young; Kim, Il

    2014-02-01

    Carbon nanostructures (CNSs) such as carbon nanotubes, graphene sheets, and nanodiamonds provide an important type of substrate for constructing a variety of hybrid nanomaterials. However, their intrinsic chemistry-inert surfaces make it indispensable to pre-functionalize them prior to immobilizing additional components onto their surfaces. Currently developed strategies for functionalizing CNSs include covalent and non-covalent approaches. Conventional covalent treatments often damage the structure integrity of carbon surfaces and adversely affect their physical properties. In contrast, the non-covalent approach offers a non-destructive way to modify CNSs with desired functional surfaces, while reserving their intrinsic properties. Thus far, a number of surface modifiers including aromatic compounds, small-molecular surfactants, amphiphilic polymers, and biomacromolecules have been developed to non-covalently functionalize CNS surfaces. Mediated by these surface modifiers, various functional components such as organic species and inorganic nanoparticles were further decorated onto their surfaces, resulting in versatile carbon-based hybrid nanomaterials with broad applications in chemical engineering and biomedical areas. In this review, the recent advances in the generation of such hybrid nanostructures based on non-covalently functionalized CNSs will be reviewed.

  20. Communicating uncertainty: managing the inherent probabilistic character of hazard estimates

    Science.gov (United States)

    Albarello, Dario

    2013-04-01

    Science is much more fixing the limits of our knowledge about possible occurrences than the identification of any "truth". This is particularly true when scientific statements concern prediction of natural phenomena largely exceeding the laboratory scale as in the case of seismogenesis. In these cases, many scenarios about future occurrences result possible (plausible) and the contribution of scientific knowledge (based on the available knowledge about underlying processes or the phenomenological studies) mainly consists in attributing to each scenario a different level of likelihood (probability). In other terms, scientific predictions in the field of geosciences (hazard assessment) are inherently probabilistic. However, despite of this, many scientist (seismologists, etc.) in communicating their position in public debates tend to stress the " truth" of their statements against the fancy character of pseudo-scientific assertions: stronger is the opposition of science and pseudo-science, more hidden becomes the probabilistic character of scientific statements. The problem arises when this kind of "probabilistic" knowledge becomes the basis of any political action (e.g., to impose expensive form of risk reducing activities): in these cases the lack of any definitive "truth" requires a direct assumption of responsibility by the relevant decider (being the single citizen or the legitimate expression of a larger community) to choose among several possibilities (however characterized by different levels of likelihood). In many cases, this can be uncomfortable and strong is the attitude to delegate to the scientific counterpart the responsibility of these decisions. This "transfer" from the genuine political field to an improper scientific context is also facilitated by the lack of a diffuse culture of "probability" outside the scientific community (and in many cases inside also). This is partially the effect of the generalized adoption (by media and scientific

  1. Auxiliary partial liver transplantation

    NARCIS (Netherlands)

    C.B. Reuvers (Cornelis Bastiaan)

    1986-01-01

    textabstractIn this thesis studies on auxiliary partial liver transplantation in the dog and the pig are reported. The motive to perform this study was the fact that patients with acute hepatic failure or end-stage chronic liver disease are often considered to form too great a risk for successful

  2. Partial Remission Definition

    DEFF Research Database (Denmark)

    Andersen, Marie Louise Max; Hougaard, Philip; Pörksen, Sven

    2014-01-01

    OBJECTIVE: To validate the partial remission (PR) definition based on insulin dose-adjusted HbA1c (IDAA1c). SUBJECTS AND METHODS: The IDAA1c was developed using data in 251 children from the European Hvidoere cohort. For validation, 129 children from a Danish cohort were followed from the onset...

  3. Fundamental partial compositeness

    DEFF Research Database (Denmark)

    Sannino, Francesco; Strumia, Alessandro; Tesi, Andrea

    2016-01-01

    We construct renormalizable Standard Model extensions, valid up to the Planck scale, that give a composite Higgs from a new fundamental strong force acting on fermions and scalars. Yukawa interactions of these particles with Standard Model fermions realize the partial compositeness scenario. Unde...

  4. Partially ordered models

    NARCIS (Netherlands)

    Fernandez, R.; Deveaux, V.

    2010-01-01

    We provide a formal definition and study the basic properties of partially ordered chains (POC). These systems were proposed to model textures in image processing and to represent independence relations between random variables in statistics (in the later case they are known as Bayesian networks).

  5. Partially Hidden Markov Models

    DEFF Research Database (Denmark)

    Forchhammer, Søren Otto; Rissanen, Jorma

    1996-01-01

    Partially Hidden Markov Models (PHMM) are introduced. They differ from the ordinary HMM's in that both the transition probabilities of the hidden states and the output probabilities are conditioned on past observations. As an illustration they are applied to black and white image compression where...

  6. Honesty in partial logic

    NARCIS (Netherlands)

    W. van der Hoek (Wiebe); J.O.M. Jaspars; E. Thijsse

    1995-01-01

    textabstractWe propose an epistemic logic in which knowledge is fully introspective and implies truth, although truth need not imply epistemic possibility. The logic is presented in sequential format and is interpreted in a natural class of partial models, called balloon models. We examine the

  7. Character feature integration of Chinese calligraphy and font

    Science.gov (United States)

    Shi, Cao; Xiao, Jianguo; Jia, Wenhua; Xu, Canhui

    2013-01-01

    A framework is proposed in this paper to effectively generate a new hybrid character type by means of integrating local contour feature of Chinese calligraphy with structural feature of font in computer system. To explore traditional art manifestation of calligraphy, multi-directional spatial filter is applied for local contour feature extraction. Then the contour of character image is divided into sub-images. The sub-images in the identical position from various characters are estimated by Gaussian distribution. According to its probability distribution, the dilation operator and erosion operator are designed to adjust the boundary of font image. And then new Chinese character images are generated which possess both contour feature of artistical calligraphy and elaborate structural feature of font. Experimental results demonstrate the new characters are visually acceptable, and the proposed framework is an effective and efficient strategy to automatically generate the new hybrid character of calligraphy and font.

  8. A Japanese logographic character frequency list for cognitive science research.

    Science.gov (United States)

    Chikamatsu, N; Yokoyama, S; Nozaki, H; Long, E; Fukuda, S

    2000-08-01

    This paper describes a Japanese logographic character (kanji) frequency list, which is based on an analysis of the largest recently available corpus of Japanese words and characters. This corpus comprised a full year of morning and evening editions of a major newspaper, containing more than 23 million kanji characters and more than 4,000 different kanji characters. This paper lists the 3,000 most frequent kanji characters, as well as an analysis of kanji usage and correlations between the present list and previous Japanese frequency lists. The authors believe that the present list will help researchers more accurately and efficiently control the selection of kanji characters in cognitive science research and interpret related psycholinguistic data.

  9. Algebraic partial Boolean algebras

    International Nuclear Information System (INIS)

    Smith, Derek

    2003-01-01

    Partial Boolean algebras, first studied by Kochen and Specker in the 1960s, provide the structure for Bell-Kochen-Specker theorems which deny the existence of non-contextual hidden variable theories. In this paper, we study partial Boolean algebras which are 'algebraic' in the sense that their elements have coordinates in an algebraic number field. Several of these algebras have been discussed recently in a debate on the validity of Bell-Kochen-Specker theorems in the context of finite precision measurements. The main result of this paper is that every algebraic finitely-generated partial Boolean algebra B(T) is finite when the underlying space H is three-dimensional, answering a question of Kochen and showing that Conway and Kochen's infinite algebraic partial Boolean algebra has minimum dimension. This result contrasts the existence of an infinite (non-algebraic) B(T) generated by eight elements in an abstract orthomodular lattice of height 3. We then initiate a study of higher-dimensional algebraic partial Boolean algebras. First, we describe a restriction on the determinants of the elements of B(T) that are generated by a given set T. We then show that when the generating set T consists of the rays spanning the minimal vectors in a real irreducible root lattice, B(T) is infinite just if that root lattice has an A 5 sublattice. Finally, we characterize the rays of B(T) when T consists of the rays spanning the minimal vectors of the root lattice E 8

  10. Stroop phenomena in the Japanese language: the case of ideographic characters (kanji) and syllabic characters (kana).

    Science.gov (United States)

    Morikawa, Y

    1981-08-01

    Utilizing a unique feature of the Japanese languages--that besides two syllabic orthographies, which have identical pronunciations, words with the same pronunciation may also be written in an orthography composed of ideographic characters--we have conducted an investigation of Stroop phenomena. The fact that pronunciations of the three Japanese orthographies are identical means that, if there are any differences between them in the Stroop phenomena observed, we can place the locus of this interference effect in the perceptual process. Five color names were written in the ideographic characters (kanji) and the two syllabic orthographies (hiragana and katakana). Color-congruent cards and incongruent cards were utilized in a color-naming task and a word-reading task. Mean required times for the color-naming condition and the word-reading conditions were compared with those for control conditions. Stroop phenomena were observed in both ideographic and syllabic orthographies. Significant differences in mean required times were observed between the ideographic and syllabic orthographies but not between the two syllabic orthographies. Interferences in comparisons of Japanese orthographies and color patch control conditions were much smaller than in the case of Stroop's (1935) experiment. A "Reverse Stroop Phenomenon" was observed only in the case of kanji on incongruent cards in the word-reading condition. The results support the hypothesis that both ideographic characters (in this case, kanji) and colors are processed in a parallel fashion in the non-dominant right cerebral hemisphere, while syllabic or phonetic characters are processed in the dominant left cerebral hemisphere.

  11. A Modified Back propagation Algorithm for Optical Character Recognition

    OpenAIRE

    Jitendra Shrivastav; Prof. Ravindra Kumar Gupta; Dr. Shailendra Singh

    2013-01-01

    Character Recognition (CR) has been an active area of research and due to its diverse applicable environment; it continues to be a challenging research topic. There is a clear need for optical character recognition in order to provide a fast and accurate method to search both existing images as well as large archives of existing paper documents. However, existing optical character recognition programs suffer from a flawed tradeoff between speed and accuracy, making it less attractive for larg...

  12. Sherlock Holmes: From literary character to pop culture symbol

    OpenAIRE

    HULCOVÁ, Anna

    2013-01-01

    The bachelor thesis Sherlock Holmes: From literary character to pop culture symbol deals with the collection of sixty detective stories by Arthur Conan Doyle, the canon. The aim of the thesis is to highlight the aspects that contributed to the popularity of Sherlock Holmes and the series as such. The character of Sherlock Holmes became one of the most adapted literary characters, which is reflected in many areas of popular culture. Special attention is paid to the recent adaptations presentin...

  13. The Strategies for Character Building through Sports Participation

    OpenAIRE

    M.S. Omar-Fauzee; Mohd Nizam Nazarudin; Yudha M. Saputra; Nina Sutresna; Duangkrai Taweesuk; Wipoj Chansem; Rozita Abd. Latif; Soh Kim Geok

    2012-01-01

    The sport participation has been a major part of our life in the societies. Studies on sports participation have found that sports have both positive and negative influence on character buildings. It has been on-going debate on whether ‘sports build character’ but through literature analysis, author had found that ‘with the intention, sports do build character.’ Therefore, strategies of building character through sports are suggested in this paper.

  14. ECOLOGICAL CULTURE IN THE UKRAINIAN NATIONAL CHARACTER

    Directory of Open Access Journals (Sweden)

    SKLADANOVSKAYA M.

    2016-07-01

    Full Text Available The ecological security of our country, the possibility of a balanced sustainable development depends on the level of formation of ecological culture of society. Purpose of the article is to analyze the ethnic origins of ecological culture of modern Ukrainian. Nature of Ukraine is the most important point of the historical development of the national character. The installation, stereotypes, archetypes influence on its formation. The aesthetic human needs are met first in the perception of the beauty of unspoiled nature, its comprehension, reflection on the eternal themes: man's place in the natural world, awareness of human relationships and nature, its impact on the individual, man's relation to the world; an effort to recreate the beauty of the surrounding environment. Development of individual aesthetic needs, a sense of harmony and disharmony is the first step of the creativity development, the creative personality possibilities, creativity abilities, which is urgently needed as a modern social development and personal improvement. This is a necessary component of ecological consciousness, ecological culture of modern man.

  15. Partially composite Higgs models

    DEFF Research Database (Denmark)

    Alanne, Tommi; Buarque Franzosi, Diogo; Frandsen, Mads T.

    2018-01-01

    We study the phenomenology of partially composite-Higgs models where electroweak symmetry breaking is dynamically induced, and the Higgs is a mixture of a composite and an elementary state. The models considered have explicit realizations in terms of gauge-Yukawa theories with new strongly...... interacting fermions coupled to elementary scalars and allow for a very SM-like Higgs state. We study constraints on their parameter spaces from vacuum stability and perturbativity as well as from LHC results and find that requiring vacuum stability up to the compositeness scale already imposes relevant...... constraints. A small part of parameter space around the classically conformal limit is stable up to the Planck scale. This is however already strongly disfavored by LHC results. in different limits, the models realize both (partially) composite-Higgs and (bosonic) technicolor models and a dynamical extension...

  16. Photogenic partial seizures.

    Science.gov (United States)

    Hennessy, M J; Binnie, C D

    2000-01-01

    To establish the incidence and symptoms of partial seizures in a cohort of patients investigated on account of known sensitivity to intermittent photic stimulation and/or precipitation of seizures by environmental visual stimuli such as television (TV) screens or computer monitors. We report 43 consecutive patients with epilepsy, who had exhibited a significant EEG photoparoxysmal response or who had seizures precipitated by environmental visual stimuli and underwent detailed assessment of their photosensitivity in the EEG laboratory, during which all were questioned concerning their ictal symptoms. All patients were considered on clinical grounds to have an idiopathic epilepsy syndrome. Twenty-eight (65%) patients reported visually precipitated attacks occurring initially with maintained consciousness, in some instances evolving to a period of confusion or to a secondarily generalized seizure. Visual symptoms were most commonly reported and included positive symptoms such as coloured circles or spots, but also blindness and subjective symptoms such as "eyes going funny." Other symptoms described included nonspecific cephalic sensations, deja-vu, auditory hallucinations, nausea, and vomiting. No patient reported any clear spontaneous partial seizures, and there were no grounds for supposing that any had partial epilepsy excepting the ictal phenomenology of some or all of the visually induced attacks. These findings provide clinical support for the physiological studies that indicate that the trigger mechanism for human photosensitivity involves binocularly innervated cells located in the visual cortex. Thus the visual cortex is the seat of the primary epileptogenic process, and the photically triggered discharges and seizures may be regarded as partial with secondary generalization.

  17. Arthroscopic partial medial meniscectomy

    Directory of Open Access Journals (Sweden)

    Dašić Žarko

    2011-01-01

    Full Text Available Background/Aim. Meniscal injuries are common in professional or recreational sports as well as in daily activities. If meniscal lesions lead to physical impairment they usually require surgical treatment. Arthroscopic treatment of meniscal injuries is one of the most often performed orthopedic operative procedures. Methods. The study analyzed the results of arthroscopic partial medial meniscectomy in 213 patients in a 24-month period, from 2006, to 2008. Results. In our series of arthroscopically treated medial meniscus tears we noted 78 (36.62% vertical complete bucket handle lesions, 19 (8.92% vertical incomplete lesions, 18 (8.45% longitudinal tears, 35 (16.43% oblique tears, 18 (8.45% complex degenerative lesions, 17 (7.98% radial lesions and 28 (13.14% horisontal lesions. Mean preoperative International Knee Documentation Committee (IKDC score was 49.81%, 1 month after the arthroscopic partial medial meniscectomy the mean IKDC score was 84.08%, and 6 months after mean IKDC score was 90.36%. Six months after the procedure 197 (92.49% of patients had good or excellent subjective postoperative clinical outcomes, while 14 (6.57% patients subjectively did not notice a significant improvement after the intervention, and 2 (0.93% patients had no subjective improvement after the partial medial meniscectomy at all. Conclusion. Arthroscopic partial medial meniscetomy is minimally invasive diagnostic and therapeutic procedure and in well selected cases is a method of choice for treatment of medial meniscus injuries when repair techniques are not a viable option. It has small rate of complications, low morbidity and fast rehabilitation.

  18. CHARACTER EDUCATION IN ISLAMIC BOARDING SCHOOL- BASED SMA AMANAH

    Directory of Open Access Journals (Sweden)

    Nana Herdiana Abdurrahman

    2016-06-01

    Full Text Available This paper aims to describe findings of the study in pesantren-based SMA Amanah covering: 1 the principal policy in developing character education, 2 the methods used in developing character education, 3 students’ characteristics as the result of the character education process, 4 the problems encountered in the implementation of character education and the efforts made in addressing the implementation of character education at the school. This study applied qualitative method using descriptive technique. The data were collected through observation, interviews, and documentation. The findings of study showed that: 1 the principal’s policy in developing character education was carried out by implementing government policies in line with the school’s vision, mission, and programs; 2 the methods used in the process of character education were through role-modelling, assignments and nurturing, habituation, training programs, and  students’ participation in various types of activities, as well as the application of rewards and punishments; 3 the student's characteristics resulted from the character  education process were piousness and devotion as well as being able to apply their knowledge and piety in everyday life; 4 problems encountered in the implementation of character education  were different values and norms students brought from home; imbalance of facilities compared to the number of students; as well as teachers’ readiness to actually implement the new program, which  was character education. Meanwhile the efforts made to overcome those problems were namely developing personal, family, neighborhood or community characters, and making commitment of all related parties/stakeholdres of SMA Amanah.

  19. Hierarchical partial order ranking

    International Nuclear Information System (INIS)

    Carlsen, Lars

    2008-01-01

    Assessing the potential impact on environmental and human health from the production and use of chemicals or from polluted sites involves a multi-criteria evaluation scheme. A priori several parameters are to address, e.g., production tonnage, specific release scenarios, geographical and site-specific factors in addition to various substance dependent parameters. Further socio-economic factors may be taken into consideration. The number of parameters to be included may well appear to be prohibitive for developing a sensible model. The study introduces hierarchical partial order ranking (HPOR) that remedies this problem. By HPOR the original parameters are initially grouped based on their mutual connection and a set of meta-descriptors is derived representing the ranking corresponding to the single groups of descriptors, respectively. A second partial order ranking is carried out based on the meta-descriptors, the final ranking being disclosed though average ranks. An illustrative example on the prioritisation of polluted sites is given. - Hierarchical partial order ranking of polluted sites has been developed for prioritization based on a large number of parameters

  20. Character and Characterization in “Palms and Men” novel

    Directory of Open Access Journals (Sweden)

    F. Khajeh pour

    Full Text Available Nowadays one of the most significant elements in story writing is character and characterization. Character in a narrative or a play, is a person that his mental and moral qualities reflect in his deeds and what he says and does. Creating such characters in a story or a novel that seem to be like real people to the reader is called characterization (Mir Sadeghi, 1382: p 85. In this article character and characterization in one of the novels about the eight year war between Iran and Iraq, calling “Palms and Men”, is investigated. Character types, methods of characterization, character appearance, prototype, the relation of character with other elements, and characterization defects are some of the subjects studied in this article.Character types: these characters are generally categorized in two groups of stereotype and type. Samir, Touraj, Reza, Hamid etc. all belong to Sepah forces category which are type characters. Some women characters such as Zeinab, Samir’s mother, Kolsoum, Hanieh’s mother etc. are stereotype characters.Methods of characterization in “Palms and Men” novel:The description of characters is done in two methods by Mr. Nematollah Soleimani:aDirect characterization: If not all the characters, most of them are certainly characterized in this way. For example in expressing Hamid’s characteristic who is the commander of the mission, he writes, “Hamid didn’t bat an eyelid in any incidents. Hamid was lion-hearted”. (Soleimani, 1380: 128. In describing uncle Heidar, he writes, “wisdom and insight, and the effects of years of suffering, difficulty, and experiencing could be clearly seen in his limpid eyes. The rural man was indeed a wise and experienced man” (the same: 264_265.bIndirect Characterization: Although in novels and long stories, direct characterization method is often used, in “Palms and Men” this kind of characterization is also appeared in different conversations, stream of consciousness, deeds

  1. Character and Characterization in “Palms and Men” novel

    Directory of Open Access Journals (Sweden)

    Fariedeh Khajehpour

    2013-11-01

    Full Text Available Abstract Nowadays one of the most significant elements in story writing is character and characterization. Character in a narrative or a play, is a person that his mental and moral qualities reflect in his deeds and what he says and does. Creating such characters in a story or a novel that seem to be like real people to the reader is called characterization (Mir Sadeghi, 1382: p 85. In this article character and characterization in one of the novels about the eight year war between Iran and Iraq, calling “Palms and Men”, is investigated. Character types, methods of characterization, character appearance, prototype, the relation of character with other elements, and characterization defects are some of the subjects studied in this article.  Character types: these characters are generally categorized in two groups of stereotype and type. Samir, Touraj, Reza, Hamid etc. all belong to Sepah forces category which are type characters. Some women characters such as Zeinab, Samir’s mother, Kolsoum, Hanieh’s mother etc. are stereotype characters.   Methods of characterization in “Palms and Men” novel:   The description of characters is done in two methods by Mr. Nematollah Soleimani:   a Direct characterization: If not all the characters, most of them are certainly characterized in this way. For example in expressing Hamid’s characteristic who is the commander of the mission, he writes, “Hamid didn’t bat an eyelid in any incidents. Hamid was lion-hearted”. (Soleimani, 1380: 128. In describing uncle Heidar, he writes, “wisdom and insight, and the effects of years of suffering, difficulty, and experiencing could be clearly seen in his limpid eyes. The rural man was indeed a wise and experienced man” (the same: 264_265.   b Indirect Characterization: Although in novels and long stories, direct characterization method is often used, in “Palms and Men” this kind of characterization is also appeared in different conversations

  2. Associations between the Application of Signature Character Strengths, Health and Well-being of Health Professionals

    Directory of Open Access Journals (Sweden)

    Melanie Hausler

    2017-07-01

    Full Text Available Previous research has shown a positive relation between character strengths, well-being and health. The aim of this analysis was to identify relations between the application of signature character strengths (ASCS at work, and well-being and health, among medical students (Study 1 and resident physicians (Study 2. We expected positive direct links between the constructs and indirect effects through emotional exhaustion. To test these hypotheses, 387 medical students in their first year and 136 resident physicians completed five scales measuring well-being, mental/physical health, character strengths, the application of their five individual signature strengths, and emotional exhaustion as an indicator of burnout. Partial correlations were examined, and mediation analyses performed. ASCS at work was positively linked with well-being and mental health but not with physical health. All links were mediated by emotional exhaustion in Study 1 and (except for mental health also in Study 2. Future studies would therefore do well to investigate the promotion of ASCS at work of people operating in medical education and its potential in fostering well-being and preventing burnout from the outset.

  3. Importance and correlations of characters for cowpea diversity in traditional varieties

    Directory of Open Access Journals (Sweden)

    Márcia Silva de Mendonça

    Full Text Available ABSTRACT Cowpea is a legume with ample plasticity, versatility and nutritional potential. It is a species widely used as a source of income and subsistence for small farmers in several Brazilian states, among them Acre. Due to the different varieties found in the State, it is the target of studies aiming at its genetic improvement. Thus, as one of the first stages of its improvement, it was aimed to determine the importance and correlations of characters for diversity and selection in traditional varieties of cowpea. The experiment was carried in completely randomized design, with plots consisting of four vase with capacity to 15.7 L, with one plant each and two replicates. The characteristics evaluated were: days for emergence, flowering (days, plant vigor (note, number of main stem nodes, apical leaflet length (mm, apical leaflet width (mm, length of pod (cm and width of the pod (cm. The correlation coefficients (phenotypic, genotypic and environmental were obtained, and the principal components analysis and the importance of the characters by the method proposed by Singh were carried out. The Singh method and principal components analysis were partially concordant in the distinction of the evaluated characters. The days for emergence, width of the apical leaflet, flowering and length of the apical leaflet were the main determinants for quantification of the genotypes and those that contributed the most to the variability of cowpea. The least discriminant characteristic by principal component analysis and recommended for discarding was plant vigor.

  4. A concise methodology for the estimation of elemental concentration effects on mesoscale cohesion of non-ferrous covalent glasses: The case of Se(80−xGe(20−xInx=0,5,10,15

    Directory of Open Access Journals (Sweden)

    Georgios S.E. Antipas

    2015-09-01

    Full Text Available The link between the electronic state and the mesoscale of covalent glasses is not settled. A functional means of addressing the mesoscale is via generalizing glass properties (e.g. such as cohesion on the basis of atomic clusters. Derivation of the most representative such cluster formations is not streamlined, however. Here, numerical pair correlation and ab initio energetic datasets are presented for the case of amorphous Selenium-rich covalent glasses, which were obtained via a new, concise methodology, relating mesoscopic cohesion to local atomic order and to the system׳s electronic structure. The methodology consisted of selecting clusters on the basis of the variation of atomic environment statistics of total coordination, partial coordination by the matrix element and cluster number density along the radial direction of a Reverse Monte Carlo supercell, the latter attained by fitting total scattering data.

  5. The Implementation of Character Education at Senior High School

    Directory of Open Access Journals (Sweden)

    Julia

    2018-01-01

    Full Text Available This paper is aimed at analyzing the implementation of character education at Senior High School in Sumedang Regency, West Java, Indonesia. A content analysis method was employed to collect the data with interviews with six teachers from six different senior high schools, which represent the rural, transitional, and urban areas. The findings revealed that: (1 not all teachers understand the concept of character education; (2 the character education has not been done systematically or has not had the specific design/model for the teaching and learning process. Most teachers embedded the character values during the teaching and learning process as a form of character education. For example, through Qur’an recitation, learning tasks, group discussion, lecture, socio-drama, observation and admonition, and even through teachers’ model. Meanwhile, outside the class, character education was implemented through competition and extracurricular activities; (3 the evaluation of character education was relatively varied, such as an observation followed by admonition, group guidance, and also focusing on behavior and affective assessment in the classroom learning process. This research implied that it is needed to make a policy on a program development through the Bureau of Education to improve Senior High School teachers’ knowledge and skills in implementing the character education.

  6. Features fusion based approach for handwritten Gujarati character recognition

    Directory of Open Access Journals (Sweden)

    Ankit Sharma

    2017-02-01

    Full Text Available Handwritten character recognition is a challenging area of research. Lots of research activities in the area of character recognition are already done for Indian languages such as Hindi, Bangla, Kannada, Tamil and Telugu. Literature review on handwritten character recognition indicates that in comparison with other Indian scripts research activities on Gujarati handwritten character recognition are very less.  This paper aims to bring Gujarati character recognition in attention. Recognition of isolated Gujarati handwritten characters is proposed using three different kinds of features and their fusion. Chain code based, zone based and projection profiles based features are utilized as individual features. One of the significant contribution of proposed work is towards the generation of large and representative dataset of 88,000 handwritten Gujarati characters. Experiments are carried out on this developed dataset. Artificial Neural Network (ANN, Support Vector Machine (SVM and Naive Bayes (NB classifier based methods are implemented for handwritten Gujarati character recognition. Experimental results show substantial enhancement over state-of-the-art and authenticate our proposals.

  7. Character combinations, convergence and diversification in ectoparasitic arthropods.

    Science.gov (United States)

    Poulin, Robert

    2009-08-01

    Different lineages of organisms diversify over time at different rates, in part as a consequence of the characteristics of the species in these lineages. Certain suites of traits possessed by species within a clade may determine rates of diversification, with some particular combinations of characters acting synergistically to either limit or promote diversification; the most successful combinations may also emerge repeatedly in different clades via convergent evolution. Here, the association between species characters and diversification is investigated amongst 21 independent lineages of arthropods ectoparasitic on vertebrate hosts. Using nine characters (each with two to four states) that capture general life history strategy, transmission mode and host-parasite interaction, each lineage was described by the set of character states it possesses. The results show, firstly, that most possible pair-wise combinations of character states have been adopted at least once, sometimes several times independently by different lineages; thus, ectoparasitic arthropods have explored most of the life history character space available to them. Secondly, lineages possessing commonly observed combinations of character states are not necessarily the ones that have experienced the highest rates of diversification (measured as a clade's species-per-genus ratio). Thirdly, some specific traits are associated with higher rates of diversification. Using more than one host per generation, laying eggs away from the host and intermediate levels of fecundity are features that appear to have promoted diversification. These findings indicate that particular species characters may be evolutionary drivers of diversity, whose effects could also apply in other taxa.

  8. Sex-Role Portrayals of Selected Female Television Characters.

    Science.gov (United States)

    Goff, David H.; And Others

    1980-01-01

    Examines the relationship between both the sex-role and the sex of viewers and viewer perception of the sex-role depicted by five female characters in prime-time television programs. Perception of character sex-role was significantly related to subject sex-role, yet unrelated to subject sex or gender. (MER)

  9. Representations of Deaf Characters in Children's Picture Books

    Science.gov (United States)

    Golos, Debbie B.; Moses, Annie M.

    2011-01-01

    Picture books can influence how children perceive people of different backgrounds, including people with disabilities whose cultures differ from their own. Researchers have examined the portrayal of multicultural characters with disabilities in children's literature. However, few have specifically considered the portrayal of deaf characters,…

  10. Affective affordances: Improving interface characters engagement through interaction.

    NARCIS (Netherlands)

    Van Vugt, H.C.; Hoorn, J.F.; Konijn, E.A.; De Bie Dimitriadou, A.

    2006-01-01

    The nature of humans interacting with interface characters (e.g. embodied agents) is not well understood. The I-PEFiC model provides an integrative perspective on human-character interaction, assuming that the processes of engagement and user interaction exchange information in explaining user

  11. Affective affordances: Improving interface character engagement through interaction

    NARCIS (Netherlands)

    van Vugt, H.C.; Hoorn, J.F.; Konijn, E.A.; de Bie Dimitriadou, A.

    2006-01-01

    The nature of humans interacting with interface characters (e.g. embodied agents) is not well understood. The I-PEFiC model provides an integrative perspective on human-character interaction, assuming that the processes of engagement and user interaction exchange information in explaining user

  12. Inculcating Character Education through EFL Teaching in Indonesian State Schools

    Science.gov (United States)

    Qoyyimah, Uswatun

    2016-01-01

    This paper describes how English as a Foreign Language (EFL) teachers in Indonesia have implemented the recent character education policy within an era of school-based curriculum reform. The character education policy required all teachers, EFL teachers included, to instil certain values in every lesson whilst the school-based curriculum reform…

  13. Building Strengths of Character: Keys to Positive Youth Development

    Science.gov (United States)

    Park, Nansook

    2009-01-01

    Character is vital force for positive development and societal well-being. Character strengths play important roles in positive youth development, not only as broad-protective factors, preventing or mitigating psychopathology and problems, but also as enabling conditions that promote thriving and flourishing. Recent research findings show that…

  14. Adult Age Differences in Processing Narrative Text: Managing Character Representations

    Science.gov (United States)

    Noh, Soo Rim

    2009-01-01

    Understanding a narrative situation depends on keeping track of multiple characters that enter and exit dynamically as the plot unfolds. Because there has been no systematic investigation of age differences in the ability to manage multiple characters during narrative comprehension, this project was designed to examine those differences in this…

  15. Dialogue and character classification in Wole Soyinka's Kongi's ...

    African Journals Online (AJOL)

    This article examines Wole Soyinka's use of dialogue-one of the major elements of drama to paint portraits of various characters in his play, Kongi's Harvest. It explores the playwright's artistic realisation of characters that can be identified and classified by what they say and what is said of them. The study concludes that with ...

  16. An interpretation of suicide and murder character elimination in ...

    African Journals Online (AJOL)

    It is noticed that women characters in particular are most likely to commit suicide when they are frustrated by something. In the selected texts, the characters who commit suicide or murder do not do so by choice, but as a result of reaching a point of absolute desperation in their lives or because of having to be loyal to ...

  17. Player-Character Dynamics in Multi- Player Role Playing Games

    DEFF Research Database (Denmark)

    Tychsen, Anders; McIlwain, D.; Brolund, T.

    2007-01-01

    This paper presents the results of a comprehensive empirical study of the impact of integrating complex game characters in multi-player Role Playing Games across tabletop and digital formats. Players were provided with characters that had detailed background history, personality and goals. Player...

  18. Dual Character Concepts and the Normative Dimension of Conceptual Representation

    Science.gov (United States)

    Knobe, Joshua; Prasada, Sandeep; Newman, George E.

    2013-01-01

    Five experiments provide evidence for a class of "dual character concepts." Dual character concepts characterize their members in terms of both (a) a set of concrete features and (b) the abstract values that these features serve to realize. As such, these concepts provide two bases for evaluating category members and two different criteria for…

  19. Preservice Secondary Teachers' Sense of Efficacy in Teaching Character Education

    Science.gov (United States)

    Waters, Stewart; Russell, William B., III

    2014-01-01

    This study investigated the personal teaching efficacy and general teaching efficacy for character education of 130 preservice secondary teachers at a large university where there were no formal courses dedicated to character education, but the topic was included in some of the content coursework. The subjects were in one teacher education program…

  20. Teaching Character Education to College Students Using Bildungsromans

    Science.gov (United States)

    Novianti, Nita

    2017-01-01

    The paper reports a study on the teaching of character education in higher education using English Bildungsroman, "Jane Eyre." The participants were 35 sixth-semester students of English Literature program in an Indonesian state university. Guided by the approach to teaching character education exemplified by Ryan & Bohlin (1999),…

  1. Sherlock Holmes Meets Othello: A MDS Analysis of Literary Characters.

    Science.gov (United States)

    Russell, G. W.; Lambert, W. B.

    1980-01-01

    Changes in college freshmen's perceptual organization of characters from "Othello" after three weeks of study and lecture were assessed using multidimensional scaling procedures. Sherlock Holmes experts also provided dissimilarity ratings of Conan Doyle's characters. Discussion centers on the extent to which the lectures on…

  2. The Development of Leader Character through Crucible Moments

    Science.gov (United States)

    Byrne, Alyson; Crossan, Mary; Seijts, Gerard

    2018-01-01

    Business schools strive to develop leadership excellence in their students. In this essay, we suggest that educators should find ways to help students develop and deepen leader character, a fundamental component of exemplary leadership. Frequently, business school students have preconceived ideas of leadership, often neglecting leader character.…

  3. Chinese character recognition based on Gabor feature extraction and CNN

    Science.gov (United States)

    Xiong, Yudian; Lu, Tongwei; Jiang, Yongyuan

    2018-03-01

    As an important application in the field of text line recognition and office automation, Chinese character recognition has become an important subject of pattern recognition. However, due to the large number of Chinese characters and the complexity of its structure, there is a great difficulty in the Chinese character recognition. In order to solve this problem, this paper proposes a method of printed Chinese character recognition based on Gabor feature extraction and Convolution Neural Network(CNN). The main steps are preprocessing, feature extraction, training classification. First, the gray-scale Chinese character image is binarized and normalized to reduce the redundancy of the image data. Second, each image is convoluted with Gabor filter with different orientations, and the feature map of the eight orientations of Chinese characters is extracted. Third, the feature map through Gabor filters and the original image are convoluted with learning kernels, and the results of the convolution is the input of pooling layer. Finally, the feature vector is used to classify and recognition. In addition, the generalization capacity of the network is improved by Dropout technology. The experimental results show that this method can effectively extract the characteristics of Chinese characters and recognize Chinese characters.

  4. Character and Citizenship Education: Conversations between Personal and Societal Values

    Science.gov (United States)

    Sim, Jasmine B.-Y.; Low, Ee Ling

    2012-01-01

    The theme of this special issue is "Character and Citizenship Education: Conversations between Personal and Societal Values." Character education and citizenship education, taken separately or as a single entity are currently riding high on the political and educational policy agendas of several governments (Arthur, 2003; Berkowitz & Bier, 2007;…

  5. Dynamic Characters with Communication Disorders in Children's Literature

    Science.gov (United States)

    Sotto, Carolyn D.; Ball, Angel L.

    2006-01-01

    Using quality children's literature with portrayals of characters that have communication impairments can be an effective teaching tool. Storybook characters with communication disorders can provide positive role models and promote understanding of diverse populations. Eighteen children's books were selected based on the following criteria:…

  6. Cultural characters of a newly recognized group of hospital staphylococci.

    Science.gov (United States)

    Jevons, M P; John, M; Parker, M T

    1966-07-01

    Members of a newly recognized group of hospital staphylococci, which are believed to have arisen from 83A staphylococci by lysogenization, differ from them in several cultural characters. Some but not all of these characters appear to be determined by the carriage of phage.

  7. character association and path coefficient analysis between some ...

    African Journals Online (AJOL)

    User

    some growth characters and grain yield in Soybean, a basis of selection for further improvement. Treatments consisted of two levels ... number of leaves as criteria for selection of Soybean for increased grain yield. Keywords: Correlation, Grain ... objective of observing the mutual relationship of different characters and also ...

  8. Keeping it wild: mapping wilderness character in the United States.

    Science.gov (United States)

    Carver, Steve; Tricker, James; Landres, Peter

    2013-12-15

    A GIS-based approach is developed to identify the state of wilderness character in US wilderness areas using Death Valley National Park (DEVA) as a case study. A set of indicators and measures are identified by DEVA staff and used as the basis for developing a flexible and broadly applicable framework to map wilderness character using data inputs selected by park staff. Spatial data and GIS methods are used to map the condition of four qualities of wilderness character: natural, untrammelled, undeveloped, and solitude or primitive and unconfined recreation. These four qualities are derived from the US 1964 Wilderness Act and later developed by Landres et al. (2008a) in "Keeping it Wild: An Interagency Strategy to Monitor Trends in Wilderness Character Across the National Wilderness Preservation System." Data inputs are weighted to reflect their importance in relation to other data inputs and the model is used to generate maps of each of the four qualities of wilderness character. The combined map delineates the range of quality of wilderness character in the DEVA wilderness revealing the majority of wilderness character to be optimal quality with the best areas in the northern section of the park. This map will serve as a baseline for monitoring change in wilderness character and for evaluating the spatial impacts of planning alternatives for wilderness and backcountry stewardship plans. The approach developed could be applied to any wilderness area, either in the USA or elsewhere in the world. Copyright © 2013 Elsevier Ltd. All rights reserved.

  9. On superconformal characters and partition functions in three dimensions

    NARCIS (Netherlands)

    Dolan, F.A.

    2010-01-01

    Possible short and semishort positive energy, unitary representations of the Osp(2N|4) superconformal group in three dimensions are discussed. Corresponding character formulas are obtained, consistent with character formulas for the SO(3,2) conformal group, revealing long multiplet decomposition at

  10. A Study of the Relationship Between Alcoholism and Character Disorder.

    Science.gov (United States)

    Wolfley, Virgil L.

    Studies have shown that sociopaths and alcoholics tend to come from similar social backgrounds and that they share several characteristics. To investigate the relationship between alcoholism and character disorder syndrome in adult males, 20 males who had a history of alcohol problems and displayed characteristics of character disorder were…

  11. Tough Self-Healing Elastomers by Molecular Enforced Integration of Covalent and Reversible Networks.

    Science.gov (United States)

    Wu, Jinrong; Cai, Li-Heng; Weitz, David A

    2017-10-01

    Self-healing polymers crosslinked by solely reversible bonds are intrinsically weaker than common covalently crosslinked networks. Introducing covalent crosslinks into a reversible network would improve mechanical strength. It is challenging, however, to apply this concept to "dry" elastomers, largely because reversible crosslinks such as hydrogen bonds are often polar motifs, whereas covalent crosslinks are nonpolar motifs. These two types of bonds are intrinsically immiscible without cosolvents. Here, we design and fabricate a hybrid polymer network by crosslinking randomly branched polymers carrying motifs that can form both reversible hydrogen bonds and permanent covalent crosslinks. The randomly branched polymer links such two types of bonds and forces them to mix on the molecular level without cosolvents. This enables a hybrid "dry" elastomer that is very tough with fracture energy 13500 Jm -2 comparable to that of natural rubber. Moreover, the elastomer can self-heal at room temperature with a recovered tensile strength 4 MPa, which is 30% of its original value, yet comparable to the pristine strength of existing self-healing polymers. The concept of forcing covalent and reversible bonds to mix at molecular scale to create a homogenous network is quite general and should enable development of tough, self-healing polymers of practical usage. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. Good character at school: Positive classroom behavior mediates the link between character strengths and school achievement

    OpenAIRE

    Wagner, Lisa; Ruch, Willibald

    2015-01-01

    Character strengths have been found to be substantially related to children’s and adolescents’ well-being. Initial evidence suggests that they also matter for school success (e.g., Weber and Ruch, 2012). The present set of two studies aimed at replicating and extending these findings in two different age groups, primary school students (N = 179; mean age = 11.6 years) and secondary school students (N = 199; mean age = 14.4 years). The students completed the VIA-Youth (Values in Action Invento...

  13. Character strengths, social anxiety, and physiological stress reactivity

    Directory of Open Access Journals (Sweden)

    Tingting Li

    2017-05-01

    Full Text Available In this paper, the effects of character strengths on the physiological reactivity to social anxiety induced by the Trier Social Stress Task were reported. On the basis of their scores in the Chinese Virtues Questionnaire, 30 college students were assigned to either high- (n = 15 or low-character-strength (n = 15 groups. Their psychological stress and physiological data across three laboratory stages (namely, baseline, stress exposure, and post-stress were collected. Results indicated that individuals with high character strengths exhibited rapid cardiovascular recovery from baseline to post-stress even if high- and low-character-strength groups showed similar patterns of cardiovascular arousal in response to the stress at baseline and stress exposure. These results prove that character strengths are stress-defense factors that allow for psychological and physiological adaptation to stress.

  14. Visual Antipriming Effect: Evidence from Chinese Character Identification

    Directory of Open Access Journals (Sweden)

    Feng Zhang

    2017-10-01

    Full Text Available Marsolek et al. (2006 have differentiated antipriming effects from priming effects, by adopting a novel priming paradigm comprised of four phases that include a baseline measurement. The general concept of antipriming supports the overlapping representation theory of knowledge. This study extended examination of the Marsolek et al. (2006 paradigm by investigating antipriming and priming effects in a series of Chinese character identification tasks. Results showed that identification accuracy of old characters was significantly higher than baseline measurements (i.e., the priming effect, while identification accuracy of novel characters was significantly lower than baseline measurements (i.e., the antipriming effect. This study demonstrates for the first time the effect of visual antipriming in Chinese character identification. It further provides new evidence for the overlapping representation theory of knowledge, and supports generalizability of the phenomenon to Chinese characters.

  15. Virtual muscularity: a content analysis of male video game characters.

    Science.gov (United States)

    Martins, Nicole; Williams, Dmitri C; Ratan, Rabindra A; Harrison, Kristen

    2011-01-01

    The 150 top-selling video games were content analyzed to study representations of male bodies. Human males in the games were captured via screenshot and body parts measured. These measurements were then compared to anthropometric data drawn from a representative sample of 1120 North American men. Characters at high levels of photorealism were larger than the average American male, but these characters did not mirror the V-shaped ideal found in mainstream media. Characters at low levels of photorealism were also larger than the average American male, but these characters were so much larger that they appeared cartoonish. Idealized male characters were more likely to be found in games for children than in games for adults. Implications for cultivation theory are discussed. Copyright © 2010 Elsevier Ltd. All rights reserved.

  16. Representations of deaf characters in children's picture books.

    Science.gov (United States)

    Golos, Debbie B; Moses, Annie M

    2011-01-01

    Picture books can influence how children perceive people of different backgrounds, including people with disabilities whose cultures differ from their own. Researchers have examined the portrayal of multicultural characters with disabilities in children's literature. However, few have specifically considered the portrayal of deaf characters, despite increased inclusion of deaf characters in children's literature over the past two decades. The present study analyzed the portrayal of deaf characters in picture books for children ages 4-8 years. A content analysis of 20 children's picture books was conducted in which the books were analyzed for messages linked to pathological and cultural categories. Results indicated that these books did not portray Deaf characters from a cultural perspective but, rather, highlighted aspects of deafness as a medical condition, one that requires fixing and that perpetuates stereotypes of deafness as a disability.

  17. Character context: a shape descriptor for Arabic handwriting recognition

    Science.gov (United States)

    Mudhsh, Mohammed; Almodfer, Rolla; Duan, Pengfei; Xiong, Shengwu

    2017-11-01

    In the handwriting recognition field, designing good descriptors are substantial to obtain rich information of the data. However, the handwriting recognition research of a good descriptor is still an open issue due to unlimited variation in human handwriting. We introduce a "character context descriptor" that efficiently dealt with the structural characteristics of Arabic handwritten characters. First, the character image is smoothed and normalized, then the character context descriptor of 32 feature bins is built based on the proposed "distance function." Finally, a multilayer perceptron with regularization is used as a classifier. On experimentation with a handwritten Arabic characters database, the proposed method achieved a state-of-the-art performance with recognition rate equal to 98.93% and 99.06% for the 66 and 24 classes, respectively.

  18. WARACS: Wrappers to Automate the Reconstruction of Ancestral Character States.

    Science.gov (United States)

    Gruenstaeudl, Michael

    2016-02-01

    Reconstructions of ancestral character states are among the most widely used analyses for evaluating the morphological, cytological, or ecological evolution of an organismic lineage. The software application Mesquite remains the most popular application for such reconstructions among plant scientists, even though its support for automating complex analyses is limited. A software tool is needed that automates the reconstruction and visualization of ancestral character states with Mesquite and similar applications. A set of command line-based Python scripts was developed that (a) communicates standardized input to and output from the software applications Mesquite, BayesTraits, and TreeGraph2; (b) automates the process of ancestral character state reconstruction; and (c) facilitates the visualization of reconstruction results. WARACS provides a simple tool that streamlines the reconstruction and visualization of ancestral character states over a wide array of parameters, including tree distribution, character state, and optimality criterion.

  19. Particle swarm optimization for automatic creation of complex graphic characters

    International Nuclear Information System (INIS)

    Fister, Iztok; Perc, Matjaž; Ljubič, Karin; Kamal, Salahuddin M.; Iglesias, Andres; Fister, Iztok

    2015-01-01

    Nature-inspired algorithms are a very promising tool for solving the hardest problems in computer sciences and mathematics. These algorithms are typically inspired by the fascinating behavior at display in biological systems, such as bee swarms or fish schools. So far, these algorithms have been applied in many practical applications. In this paper, we present a simple particle swarm optimization, which allows automatic creation of complex two-dimensional graphic characters. The method involves constructing the base characters, optimizing the modifications of the base characters with the particle swarm optimization algorithm, and finally generating the graphic characters from the solution. We demonstrate the effectiveness of our approach with the creation of simple snowman, but we also outline in detail how more complex characters can be created

  20. Membangun Karakter Anak Usia Dini melalui Pembelajaran Math Character

    Directory of Open Access Journals (Sweden)

    Titin Faridatun Nisa’

    2016-09-01

    Full Text Available Penelitian ini bertujuan untuk mengetahui penerapan pembelajaran math character untuk membangun karakter Anak Usia Dini (AUD dan kesulitan-kesulitan yang dialami guru dalam penerapan pembelajaran math character. Target penelitian ini adalah terbentuknya karakter anak usia dini melalui pembelajaran math character. Jenis penelitian ini adalah penelitian deskriptif dengan metode penelitian kualitatif. Teknik pengumpulan informasi penelitian ini dengan metode observasi dan wawancara. Analisis data penelitian ini menggunakan analisis deskriptif. Hasil penelitian menunjukkan bahwa penerapan pembelajaran math character dapat membangun delapan belas nilai-nilai karakter AUD. Kesulitan-kesulitan yang dialami guru dalam pembentukan karakter AUD melalui pembelajaran math character meliputi tema yang digunakan termasuk tema baru, siswa belum terbiasa dengan pembelajaran berbasis sentra, usia siswa bervariasi, dan adanya ikut campur wali siswa dalam kegiatan pembelajaran di kelas sehingga siswa menjadi kurang mandiri.

  1. Playing MMORPGs: connections between addiction and identifying with a character.

    Science.gov (United States)

    Smahel, David; Blinka, Lukas; Ledabyl, Ondrej

    2008-12-01

    Addiction to online role-playing games is one of the most discussed aspects of recent cyberpsychology, mainly for its potentially negative impact on the social lives of young people. In our study, we focus on some aspects of youth and adolescent addiction to MMORPGs. We investigated connections between players and their game characters and examined if, and in what ways, player relationship to their character affected potential addiction. Players attitude to their characters seems to play a specific role, since players who tend to be addicted view their characters as being superior and more often wish to be like their characters in their real lives. Our research also confirmed that younger players are generally more prone to addiction.

  2. [The study of transpiration influence on plant infrared radiation character].

    Science.gov (United States)

    Ling, Jun; Zhang, Shuan-Qin; Pan, Jia-Liang; Lian, Chang-Chun; Yang, Hui

    2012-07-01

    Studying vegetation infrared radiation character is the base of developing infrared camouflage and concealment technology of ground military target. Accurate fusion of target and background can be achieved by simulating formation mechanism of vegetation infrared radiation character. Leaf transpiration is characteristic physiological mechanism of vegetation and one of the main factors that influence its infrared radiation character. In the present paper, physical model of leaf energy balance is set up. Based on this model the influence of plant transpiration on leaf temperature is analyzed and calculated. The daily periodic variation of transpiration, leaf temperature and infrared radiation character of typical plants such as camphor tree and holly is actually measured with porometer and infrared thermal imaging system. By contrasting plant leaf with dryness leaf, experimental data indicates that plant transpiration can regulate leaf energy balance effectively and control leaf temperature in a reasonable range and suppress deep range variation of leaf infrared radiation character.

  3. Suicide inactivation of cytochrome P-450 by methoxsalen. Evidence for the covalent binding of a reactive intermediate to the protein moiety

    International Nuclear Information System (INIS)

    Labbe, G.; Descatoire, V.; Beaune, P.; Letteron, P.; Larrey, D.; Pessayre, D.

    1989-01-01

    Incubation of rat liver microsomes with [3H]methoxsalen and NADPH resulted in the covalent binding of a methoxsalen intermediate to proteins comigrating with cytochromes P-450 UT-A, PB-B/D, ISF-G and PCN-E. Binding was increased by pretreatments with phenobarbital, beta-naphthoflavone (beta NF) and dexamethasone. Such pretreatments also increased the loss of CO-binding capacity either after administration of methoxsalen, or after incubation of hepatic microsomes with methoxsalen and NADPH. Immunoprecipitation of the methoxsalen metabolite-protein adducts in phenobarbital-induced microsomes was moderate with anti-UT-A antibodies, but marked with anti-PB-B/D and anti-PCN-E antibodies. Immunoprecipitation was observed also with anti-ISF-G (anti-beta NF-B) antibodies in beta NF-induced microsomes. Methoxsalen (0.25 mM) inhibited markedly the benzphetamine demethylase activity of phenobarbital-induced microsomes and the erythromycin demethylase activity of dexamethasone-induced microsomes. Whereas methoxsalen itself did not produce any binding spectrum, in contrast either in vivo administration of methoxsalen or incubation in vitro with methoxsalen and NADPH resulted in a low-to-high spin conversion of cytochrome P-450 as suggested by the appearance of a spectrum analogous to a type I binding spectrum. This low-to-high spin conversion was apparently due to a methoxsalen intermediate (probably, covalently bound to the protein and preventing partial sixth ligation of the iron). We conclude that suicide inactivation of cytochrome P-450 by methoxsalen is related to the covalent binding of a methoxsalen intermediate to the protein moiety of several cytochrome P-450 isoenzymes (including UT-A, PB-B/D, PCN-E as well as ISF-G and/or beta NF-B)

  4. Partially ordered algebraic systems

    CERN Document Server

    Fuchs, Laszlo

    2011-01-01

    Originally published in an important series of books on pure and applied mathematics, this monograph by a distinguished mathematician explores a high-level area in algebra. It constitutes the first systematic summary of research concerning partially ordered groups, semigroups, rings, and fields. The self-contained treatment features numerous problems, complete proofs, a detailed bibliography, and indexes. It presumes some knowledge of abstract algebra, providing necessary background and references where appropriate. This inexpensive edition of a hard-to-find systematic survey will fill a gap i

  5. Infinite partial summations

    International Nuclear Information System (INIS)

    Sprung, D.W.L.

    1975-01-01

    This paper is a brief review of those aspects of the effective interaction problem that can be grouped under the heading of infinite partial summations of the perturbation series. After a brief mention of the classic examples of infinite summations, the author turns to the effective interaction problem for two extra core particles. Their direct interaction is summed to produce the G matrix, while their indirect interaction through the core is summed in a variety of ways under the heading of core polarization. (orig./WL) [de

  6. On universal partial words

    OpenAIRE

    Chen, Herman Z. Q.; Kitaev, Sergey; Mütze, Torsten; Sun, Brian Y.

    2016-01-01

    A universal word for a finite alphabet $A$ and some integer $n\\geq 1$ is a word over $A$ such that every word in $A^n$ appears exactly once as a subword (cyclically or linearly). It is well-known and easy to prove that universal words exist for any $A$ and $n$. In this work we initiate the systematic study of universal partial words. These are words that in addition to the letters from $A$ may contain an arbitrary number of occurrences of a special `joker' symbol $\\Diamond\

  7. Partial differential equations

    CERN Document Server

    Agranovich, M S

    2002-01-01

    Mark Vishik's Partial Differential Equations seminar held at Moscow State University was one of the world's leading seminars in PDEs for over 40 years. This book celebrates Vishik's eightieth birthday. It comprises new results and survey papers written by many renowned specialists who actively participated over the years in Vishik's seminars. Contributions include original developments and methods in PDEs and related fields, such as mathematical physics, tomography, and symplectic geometry. Papers discuss linear and nonlinear equations, particularly linear elliptic problems in angles and gener

  8. Partial differential equations

    CERN Document Server

    Levine, Harold

    1997-01-01

    The subject matter, partial differential equations (PDEs), has a long history (dating from the 18th century) and an active contemporary phase. An early phase (with a separate focus on taut string vibrations and heat flow through solid bodies) stimulated developments of great importance for mathematical analysis, such as a wider concept of functions and integration and the existence of trigonometric or Fourier series representations. The direct relevance of PDEs to all manner of mathematical, physical and technical problems continues. This book presents a reasonably broad introductory account of the subject, with due regard for analytical detail, applications and historical matters.

  9. Partial differential equations

    CERN Document Server

    Sloan, D; Süli, E

    2001-01-01

    /homepage/sac/cam/na2000/index.html7-Volume Set now available at special set price ! Over the second half of the 20th century the subject area loosely referred to as numerical analysis of partial differential equations (PDEs) has undergone unprecedented development. At its practical end, the vigorous growth and steady diversification of the field were stimulated by the demand for accurate and reliable tools for computational modelling in physical sciences and engineering, and by the rapid development of computer hardware and architecture. At the more theoretical end, the analytical insight in

  10. Elliptic partial differential equations

    CERN Document Server

    Han, Qing

    2011-01-01

    Elliptic Partial Differential Equations by Qing Han and FangHua Lin is one of the best textbooks I know. It is the perfect introduction to PDE. In 150 pages or so it covers an amazing amount of wonderful and extraordinary useful material. I have used it as a textbook at both graduate and undergraduate levels which is possible since it only requires very little background material yet it covers an enormous amount of material. In my opinion it is a must read for all interested in analysis and geometry, and for all of my own PhD students it is indeed just that. I cannot say enough good things abo

  11. Generalized Partial Volume

    DEFF Research Database (Denmark)

    Darkner, Sune; Sporring, Jon

    2011-01-01

    Mutual Information (MI) and normalized mutual information (NMI) are popular choices as similarity measure for multimodal image registration. Presently, one of two approaches is often used for estimating these measures: The Parzen Window (PW) and the Generalized Partial Volume (GPV). Their theoret...... of view as well as w.r.t. computational complexity. Finally, we present algorithms for both approaches for NMI which is comparable in speed to Sum of Squared Differences (SSD), and we illustrate the differences between PW and GPV on a number of registration examples....

  12. ANALYSIS OF THE INTERACTIONS BETWEEN IMMIGRANT/FOREIGN CHARACTERS AND NATIONAL/AUTOCHTHONOUS CHARACTERS IN SPANISH TELEVISION FICTION

    Directory of Open Access Journals (Sweden)

    María Marcos Ramos

    2014-10-01

    Full Text Available In this paper we present the results of an empirical research in which it were analysed the interactions between immigrants and national characters in a sample of Spanish television fictional programs broadcasted on prime time. This study is a content analysis of 282 interactions between immigrant/foreign and national characters. Thus, it was found that the largest number of relationships between the characters involved was produced in a working context. Moreover, there was a higher proportion of the use of aggressive humour from the national characters to the immigrant/foreigners than in the reverse way. It was also observed that the immigrant/foreigner characters hardly spoke about their feelings, nor were heard by the nationals when they did it, although there were a high number of interactions in which immigrant characters were expressing their opinions and these were attended by national characters. The analysis of the interactions between immigrant and national characters in television fiction is a very important research issue, because it has been proposed that the parasocial interactions are complementary of the interpersonal interactions taking place in daily life (Müller, 2009; Park, 2012.

  13. The Effect of Realistic Appearance of Virtual Characters in Immersive Environments - Does the Character's Personality Play a Role?

    Science.gov (United States)

    Zibrek, Katja; Kokkinara, Elena; Mcdonnell, Rachel

    2018-04-01

    Virtual characters that appear almost photo-realistic have been shown to induce negative responses from viewers in traditional media, such as film and video games. This effect, described as the uncanny valley, is the reason why realism is often avoided when the aim is to create an appealing virtual character. In Virtual Reality, there have been few attempts to investigate this phenomenon and the implications of rendering virtual characters with high levels of realism on user enjoyment. In this paper, we conducted a large-scale experiment on over one thousand members of the public in order to gather information on how virtual characters are perceived in interactive virtual reality games. We were particularly interested in whether different render styles (realistic, cartoon, etc.) would directly influence appeal, or if a character's personality was the most important indicator of appeal. We used a number of perceptual metrics such as subjective ratings, proximity, and attribution bias in order to test our hypothesis. Our main result shows that affinity towards virtual characters is a complex interaction between the character's appearance and personality, and that realism is in fact a positive choice for virtual characters in virtual reality.

  14. "It Could Affect You as a Person, Character-Wise": Promoting Character Development and Preventing Sexual Violence at West Point

    Science.gov (United States)

    Arbeit, Miriam R.

    2017-01-01

    The United States Military Academy at West Point develops cadets into "leaders of character" who will become Army officers. This focus on character presents an opportunity for the prevention of sexual violence through an emphasis on military values. Using constructivist grounded theory, this study examined how cadets experience their own…

  15. Data in support of covalent attachment of tyrosinase onto cyanuric chloride crosslinked magnetic nanoparticles

    Directory of Open Access Journals (Sweden)

    Kourosh Abdollahi

    2016-12-01

    Full Text Available Preparation and characterization of cross linked amine-functionalized magnetic nanoparticles as an appropriate support for covalent immobilization on tyrosinase was presented in the study "Covalent immobilization of tyrosinase onto cyanuric chloride crosslinked amine-functionalized superparamagnetic nanoparticles: synthesis and characterization of the recyclable nanobiocatalyst" (Abdollahi et al., 2016 [1]. Herein, complementary data regarding X-ray powder diffraction (XRD to characterize the synthesized magnetic nanoparticles, and transmission electron microscopy (TEM to determine the size and morphology of tyrosinase immobilized magnetic nanoparticles (tyrosinase-MNPs were reported. The purification results of the extracted tyrosinase from mushroom Agaricus bisporus were provided in a purification table. The covalent immobilization of tyrosinase onto cyanuric chloride functionalized magnetic nanoparticles was proved by performing thermo-gravimetric and energy-dispersive X-ray spectroscopy analyses. The operational stability of immobilized tyrosinase was investigated by incubating tyrosinase-MNPs at different pH and temperatures.

  16. Unanticipated C=C bonds in covalent monolayers on silicon revealed by NEXAFS.

    Science.gov (United States)

    Lee, Michael V; Lee, Jonathan R I; Brehmer, Daniel E; Linford, Matthew R; Willey, Trevor M

    2010-02-02

    Interfaces are crucial to material properties. In the case of covalent organic monolayers on silicon, molecular structure at the interface controls the self-assembly of the monolayers, which in turn influences the optical properties and electrical transport. These properties intrinsically affect their application in biology, tribology, optics, and electronics. We use near-edge X-ray absorption fine structure spectroscopy to show that the most basic covalent monolayers formed from 1-alkenes on silicon retain a double bond in one-fifth to two-fifths of the resultant molecules. Unsaturation in the predominantly saturated monolayers will perturb the regular order and affect the dependent properties. The presence of unsaturation in monolayers produced by two different methods also prompts the re-evaluation of other radical-based mechanisms for forming covalent monolayers on silicon.

  17. Applications of covalent organic frameworks (COFs): From gas storage and separation to drug delivery

    Institute of Scientific and Technical Information of China (English)

    Ming-Xue Wu; Ying-Wei Yang

    2017-01-01

    Covalent organic frameworks (COFs) are an emerging class of porous covalent organic structures whose backbones were composed of light elements (B,C,N,O,Si) and linked by robust covalent bonds to endow such material with desirable properties,i.e.,inherent porosity,well-defined pore aperture,ordered channel structure,large surface area,high stability,and multi-dimension.As expected,the abovementioned properties of COFs broaden the applications of this class of materials in various fields such as gas storage and separation,catalysis,optoelectronics,sensing,small molecules adsorption,and drug delivery.In this review,we outlined the synthesis of COFs and highlighted their applications ranging from the initial gas storage and separation to drug delivery.

  18. On-surface synthesis of covalent coordination polymers on micrometer scale

    Institute of Scientific and Technical Information of China (English)

    Mathieu Koudia; Elena Nardi; Olivier Siri; Mathieu Abel

    2017-01-01

    On-surface synthesis under ultrahigh vacuum provides a promising strategy to control matter at the atomic level,with important implications for the design of new two-dimensional materials having remarkable electronic,magnetic,or catalytic properties.This strategy must address the problem of limited extension of the domains due to the irreversible nature of covalent bonds,which prevents the ripening of defects.We show here that extended materials can be produced by a controlled co-deposition process.In particular,co-deposition of quinoid zwitterion molecules with iron atoms on a Ag(111) surface held at 570 K allows the formation of micrometer-sized domains based on covalent coordination bonds.This work opens up the construction of micrometer-scale single-layer covalent coordination materials under vacuum conditions.

  19. Novel covalently linked insulin dimer engineered to investigate the function of insulin dimerization

    DEFF Research Database (Denmark)

    Vinther, Tine N.; Norrman, Mathias; Strauss, Holger M.

    2012-01-01

    An ingenious system evolved to facilitate insulin binding to the insulin receptor as a monomer and at the same time ensure sufficient stability of insulin during storage. Insulin dimer is the cornerstone of this system. Insulin dimer is relatively weak, which ensures dissociation into monomers...... in the circulation, and it is stabilized by hexamer formation in the presence of zinc ions during storage in the pancreatic ß-cell. Due to the transient nature of insulin dimer, direct investigation of this important form is inherently difficult. To address the relationship between insulin oligomerization...... and insulin stability and function, we engineered a covalently linked insulin dimer in which two monomers were linked by a disulfide bond. The structure of this covalent dimer was identical to the self-association dimer of human insulin. Importantly, this covalent dimer was capable of further oligomerization...

  20. Molecular Simulation Studies of Covalently and Ionically Grafted Nanoparticles

    Science.gov (United States)

    Hong, Bingbing

    Solvent-free covalently- or ionically-grafted nanoparticles (CGNs and IGNs) are a new class of organic-inorganic hybrid composite materials exhibiting fluid-like behaviors around room temperature. With similar structures to prior systems, e.g. nanocomposites, neutral or charged colloids, ionic liquids, etc, CGNs and IGNs inherit the functionality of inorganic nanopariticles, the facile processibility of polymers, as well as conductivity and nonvolatility from their constituent materials. In spite of the extensive prior experimental research having covered synthesis and measurements of thermal and dynamic properties, little progress in understanding of these new materials at the molecular level has been achieved, because of the lack of simulation work in this new area. Atomistic and coarse-grained molecular dynamics simulations have been performed in this thesis to investigate the thermodynamics, structure, and dynamics of these systems and to seek predictive methods predictable for their properties. Starting from poly(ethylene oxide) oligomers (PEO) melts, we established atomistic models based on united-atom representations of methylene. The Green-Kubo and Einstein-Helfand formulas were used to calculate the transport properties. The simulations generate densities, viscosities, diffusivities, in good agreement with experimental data. The chain-length dependence of the transport properties suggests that neither Rouse nor reptation models are applicable in the short-chain regime investigated. Coupled with thermodynamic integration methods, the models give good predictions of pressure-composition-density relations for CO 2 + PEO oligomers. Water effects on the Henry's constant of CO 2 in PEO have also been investigated. The dependence of the calculated Henry's constants on the weight percentage of water falls on a temperature-dependent master curve, irrespective of PEO chain length. CGNs are modeled by the inclusion of solid-sphere nanoparticles into the atomistic

  1. Merging constitutional and motional covalent dynamics in reversible imine formation and exchange processes.

    Science.gov (United States)

    Kovaříček, Petr; Lehn, Jean-Marie

    2012-06-06

    The formation and exchange processes of imines of salicylaldehyde, pyridine-2-carboxaldehyde, and benzaldehyde have been studied, showing that the former has features of particular interest for dynamic covalent chemistry, displaying high efficiency and fast rates. The monoimines formed with aliphatic α,ω-diamines display an internal exchange process of self-transimination type, inducing a local motion of either "stepping-in-place" or "single-step" type by bond interchange, whose rate decreases rapidly with the distance of the terminal amino groups. Control of the speed of the process over a wide range may be achieved by substituents, solvent composition, and temperature. These monoimines also undergo intermolecular exchange, thus merging motional and constitutional covalent behavior within the same molecule. With polyamines, the monoimines formed execute internal motions that have been characterized by extensive one-dimensional, two-dimensional, and EXSY proton NMR studies. In particular, with linear polyamines, nondirectional displacement occurs by shifting of the aldehyde residue along the polyamine chain serving as molecular track. Imines thus behave as simple prototypes of systems displaying relative motions of molecular moieties, a subject of high current interest in the investigation of synthetic and biological molecular motors. The motional processes described are of dynamic covalent nature and take place without change in molecular constitution. They thus represent a category of dynamic covalent motions, resulting from reversible covalent bond formation and dissociation. They extend dynamic covalent chemistry into the area of molecular motions. A major further step will be to achieve control of directionality. The results reported here for imines open wide perspectives, together with other chemical groups, for the implementation of such features in multifunctional molecules toward the design of molecular devices presenting a complex combination of

  2. Unilateral removable partial dentures.

    Science.gov (United States)

    Goodall, W A; Greer, A C; Martin, N

    2017-01-27

    Removable partial dentures (RPDs) are widely used to replace missing teeth in order to restore both function and aesthetics for the partially dentate patient. Conventional RPD design is frequently bilateral and consists of a major connector that bridges both sides of the arch. Some patients cannot and will not tolerate such an extensive appliance. For these patients, bridgework may not be a predictable option and it is not always possible to provide implant-retained restorations. This article presents unilateral RPDs as a potential treatment modality for such patients and explores indications and contraindications for their use, including factors relating to patient history, clinical presentation and patient wishes. Through case examples, design, material and fabrication considerations will be discussed. While their use is not widespread, there are a number of patients who benefit from the provision of unilateral RPDs. They are a useful treatment to have in the clinician's armamentarium, but a highly-skilled dental team and a specific patient presentation is required in order for them to be a reasonable and predictable prosthetic option.

  3. Combination of computational methods, adsorption isotherms and selectivity tests for the conception of a mixed non-covalent-semi-covalent molecularly imprinted polymer of vanillin.

    Science.gov (United States)

    Puzio, Kinga; Delépée, Raphaël; Vidal, Richard; Agrofoglio, Luigi A

    2013-08-06

    A novel molecularly imprinted polymer (MIP) for vanillin was prepared by photo initiated polymerization in dichloromethane using a mixed semi-covalent and non-covalent imprinting strategy. Taking polymerisable syringaldehyde as "dummy" template, acrylamide was chosen as functional monomer on B3LYP/6-31+G(d,p) density functional theory computational method basis with counterpoise. The binding parameters for the recognition of vanillin on imprinted polymers were studied with three different isotherm models (Langmuir, bi-Langmuir and Langmuir-Freundlich) and compared. The results indicate an heterogeneity of binding sites. It was found and proved by DFT calculations that the specific binding of vanillin in the cavities is due to non-covalent interactions of the template with the hydroxyphenyl- and the amide-moieties. The binding geometry of vanillin in the MIP cavity was also modelled. The obtained MIP is highly specific for vanillin (with an imprinting factor of 7.4) and was successfully applied to the extraction of vanillin from vanilla pods, red wine spike with vanillin, natural and artificial vanilla sugar with a recovery of 80%. Copyright © 2013 Elsevier B.V. All rights reserved.

  4. Virtual Character Personality Influences Participant Attitudes and Behavior - An Interview with a Virtual Human Character about Her Social Anxiety

    Directory of Open Access Journals (Sweden)

    Xueni ePan

    2015-02-01

    Full Text Available We introduce a novel technique for the study of human-virtual character interaction in immersive virtual reality. The human participants verbally administered a standard questionnaire about social anxiety to a virtual female character, that responded to each question through speech and body movements. The purpose was to study the extent to which participants responded differently to characters that exhibited different personalities, even though the verbal content of their answers was always the same. A separate online study provided evidence that our intention to create two different personality types had been successful. In the main between-groups experiment that utilized a Cave system there were 24 male participants, where 12 interacted with a female virtual character portrayed to exhibit shyness and the remaining 12 with an identical but more confident virtual character. Our results indicate that although the content of the verbal responses of both virtual characters was the same, participants showed different subjective and behavioral responses to the two different personalities. In particular participants evaluated the shy character more positively, for example, expressing willingness to spend more time with her. Participants evaluated the confident character more negatively and waited for a significantly longer time to call her back after she had left the scene in order to answer a telephone call. The method whereby participants interviewed the virtual character allowed naturalistic conversation while avoiding the necessity of speech processing and generation, and natural language understanding. It is therefore a useful method for the study of the impact of virtual character personality on participant responses.

  5. Preparation and fluorescent recognition properties for fluoride of a nanostructured covalently bonded europium hybrid material

    Institute of Scientific and Technical Information of China (English)

    余旭东; 李景印; 李亚娟; 耿丽君; 甄小丽; 于涛

    2015-01-01

    A novel covalently bonded Eu3+-based silica hybrid material was designed and its spectrophotometric anion sensing prop-erty was studied. The fluorescent receptor (europium complex) was covalently grafted to the silica matrix via a sol-gel approach. FTIR, UV-vis spectra, scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD) and photoluminescent spectra were characterized, and the results revealed that the hybrid material with nanosphere structure displayed excellent photophysical property. In addition, the selective anion sensing property of the hybrid material was studied by UV-vis and fluorescence spectra. The results showed that the hybrid material exhibited a smart response with fluoride anions.

  6. Investigation of Non-Covalent Interactions of Aflatoxins (B1, B2, G1, G2, and M1 with Serum Albumin

    Directory of Open Access Journals (Sweden)

    Miklós Poór

    2017-10-01

    Full Text Available Aflatoxins are widely spread mycotoxins produced mainly by Aspergillus species. Consumption of aflatoxin-contaminated foods and drinks causes serious health risks for people worldwide. It is well-known that the reactive epoxide metabolite of aflatoxin B1 (AFB1 forms covalent adducts with serum albumin. However, non-covalent interactions of aflatoxins with human serum albumin (HSA are poorly characterized. Thus, in this study the complex formation of aflatoxins was examined with HSA applying spectroscopic and molecular modelling studies. Our results demonstrate that aflatoxins form stable complexes with HSA as reflected by binding constants between 2.1 × 104 and 4.5 × 104 dm3/mol. A binding free energy value of −26.90 kJ mol−1 suggests a spontaneous binding process between AFB1 and HSA at room-temperature, while the positive entropy change of 55.1 JK−1 mol−1 indicates a partial decomposition of the solvation shells of the interacting molecules. Modeling studies and investigations with site markers suggest that Sudlow’s Site I of subdomain IIA is the high affinity binding site of aflatoxins on HSA. Interaction of AFB1 with bovine, porcine, and rat serum albumins was also investigated. Similar stabilities of the examined AFB1-albumin complexes were observed suggesting the low species differences of the albumin-binding of aflatoxins.

  7. Moral character predominates in person perception and evaluation.

    Science.gov (United States)

    Goodwin, Geoffrey P; Piazza, Jared; Rozin, Paul

    2014-01-01

    What sorts of trait information do people most care about when forming impressions of others? Recent research in social cognition suggests that "warmth," broadly construed, should be of prime importance in impression formation. Yet, some prior research suggests that information about others' specifically moral traits--their moral "character"--may be a primary dimension. Although warmth and character have sometimes been conceived of as interchangeable, we argue that they are separable, and that across a wide variety of contexts, character is usually more important than warmth in impression formation. We first showed that moral character and social warmth traits are indeed separable (Studies 1 and 2). Further studies that used correlational and experimental methods showed that, as predicted, in most contexts, moral character information is more important in impression formation than is warmth information (Studies 2-6). Character information was also more important than warmth information with respect to judgments of traits' perceived fundamentalness to identity, their uniquely human quality, their context-independence, and their controllability (Study 2). Finally, Study 7 used an archival method to show that moral character information appears more prominently than warmth information in obituaries, and more strongly determines the impressions people form of the individuals described in those obituaries. We discuss implications for current theories of person perception and social cognition.

  8. Tutorial on Online Partial Evaluation

    Directory of Open Access Journals (Sweden)

    William R. Cook

    2011-09-01

    Full Text Available This paper is a short tutorial introduction to online partial evaluation. We show how to write a simple online partial evaluator for a simple, pure, first-order, functional programming language. In particular, we show that the partial evaluator can be derived as a variation on a compositionally defined interpreter. We demonstrate the use of the resulting partial evaluator for program optimization in the context of model-driven development.

  9. Type-Directed Partial Evaluation

    DEFF Research Database (Denmark)

    Danvy, Olivier

    1998-01-01

    Type-directed partial evaluation uses a normalization function to achieve partial evaluation. These lecture notes review its background, foundations, practice, and applications. Of specific interest is the modular technique of offline and online type-directed partial evaluation in Standard ML...

  10. Type-Directed Partial Evaluation

    DEFF Research Database (Denmark)

    Danvy, Olivier

    1998-01-01

    Type-directed partial evaluation uses a normalization function to achieve partial evaluation. These lecture notes review its background, foundations, practice, and applications. Of specific interest is the modular technique of offline and online type-directed partial evaluation in Standard ML of ...

  11. Calculation of partial derivatives of thermophysical properties of sodium for safety analysis

    International Nuclear Information System (INIS)

    Shan Jianqiang; Qiu Suizhang; Zhu Jizhou; Zhang Guiqin

    1997-01-01

    According to the characters of safety analysis of LMFBR, the partial derivatives formula of some special thermophysical properties of sodium, including single-and two-phase properties, are calculated based on the basic Maxwell equations, and on the formulae of basic thermophysical properties of sodium which were verified abroad. The present study can provide theoretical base for safety analysis of LMFBR

  12. [The representation of madness in William Shakespeare's characters].

    Science.gov (United States)

    Stompe, Thomas; Ritter, Kristina; Friedmann, Alexander

    2006-08-01

    Shakespeare is one of the great creators of human characters of the 16(th) century. Like for many of his contemporaries madness was a central topic of his work. The first part of this paper discusses the sociocultural environment and the semantic field of madness in the Elizabethan age, which forms the background for Shakespeare's characters. In the second part we try to analyze the clinical pictures of the fictive characters of Othello, Hamlet, Lear and Macbeth. While we find melancholy, delusions and hallucinations, other diseases such as schizophrenia are missing entirely. Schizophrenia only appears in the literature more than two hundred years later, in the beginning of modern age.

  13. A cognitive network for oracle bone characters related to animals

    Science.gov (United States)

    Dress, Andreas; Grünewald, Stefan; Zeng, Zhenbing

    2016-01-01

    In this paper, we present an analysis of oracle bone characters for animals from a “cognitive” point of view. After some general remarks on oracle-bone characters presented in Sec. 1 and a short outline of the paper in Sec. 2, we collect various oracle-bone characters for animals from published resources in Sec. 3. In the next section, we begin analyzing a group of 60 ancient animal characters from www.zdic.net, a highly acclaimed internet dictionary of Chinese characters that is strictly based on historical sources, and introduce five categories of specific features regarding their (graphical) structure that will be used in Sec. 5 to associate corresponding feature vectors to these characters. In Sec. 6, these feature vectors will be used to investigate their dissimilarity in terms of a family of parameterized distance measures. And in the last section, we apply the SplitsTree method as encoded in the NeighborNet algorithms to construct a corresponding family of dissimilarity-based networks with the intention of elucidating how the ancient Chinese might have perceived the “animal world” in the late bronze age and to demonstrate that these pictographs reflect an intuitive understanding of this world and its inherent structure that predates its classification in the oldest surviving Chinese encyclopedia from approximately the third century BC, the Er Ya, as well as similar classification systems in the West by one to two millennia. We also present an English dictionary of 70 oracle bone characters for animals in Appendix A. In Appendix B, we list various variants of animal characters that were published in the Jia Gu Wen Bian (cf. 甲骨文编, A Complete Collection of Oracle Bone Characters, edited by the Institute of Archaeology of the Chinese Academy of Social Sciences, published by the Zhonghua Book Company in 1965). We recall the frequencies of the 521 most frequent oracle bone characters in Appendix C as reported in [T. Chen, Yin-Shang Jiaguwen Zixing

  14. Applied partial differential equations

    CERN Document Server

    Logan, J David

    2004-01-01

    This primer on elementary partial differential equations presents the standard material usually covered in a one-semester, undergraduate course on boundary value problems and PDEs. What makes this book unique is that it is a brief treatment, yet it covers all the major ideas: the wave equation, the diffusion equation, the Laplace equation, and the advection equation on bounded and unbounded domains. Methods include eigenfunction expansions, integral transforms, and characteristics. Mathematical ideas are motivated from physical problems, and the exposition is presented in a concise style accessible to science and engineering students; emphasis is on motivation, concepts, methods, and interpretation, rather than formal theory. This second edition contains new and additional exercises, and it includes a new chapter on the applications of PDEs to biology: age structured models, pattern formation; epidemic wave fronts, and advection-diffusion processes. The student who reads through this book and solves many of t...

  15. Inductance loop and partial

    CERN Document Server

    Paul, Clayton R

    2010-01-01

    "Inductance is an unprecedented text, thoroughly discussing "loop" inductance as well as the increasingly important "partial" inductance. These concepts and their proper calculation are crucial in designing modern high-speed digital systems. World-renowned leader in electromagnetics Clayton Paul provides the knowledge and tools necessary to understand and calculate inductance." "With the present and increasing emphasis on high-speed digital systems and high-frequency analog systems, it is imperative that system designers develop an intimate understanding of the concepts and methods in this book. Inductance is a much-needed textbook designed for senior and graduate-level engineering students, as well as a hands-on guide for working engineers and professionals engaged in the design of high-speed digital and high-frequency analog systems."--Jacket.

  16. Fundamental partial compositeness

    CERN Document Server

    Sannino, Francesco

    2016-11-07

    We construct renormalizable Standard Model extensions, valid up to the Planck scale, that give a composite Higgs from a new fundamental strong force acting on fermions and scalars. Yukawa interactions of these particles with Standard Model fermions realize the partial compositeness scenario. Successful models exist because gauge quantum numbers of Standard Model fermions admit a minimal enough 'square root'. Furthermore, right-handed SM fermions have an SU(2)$_R$-like structure, yielding a custodially-protected composite Higgs. Baryon and lepton numbers arise accidentally. Standard Model fermions acquire mass at tree level, while the Higgs potential and flavor violations are generated by quantum corrections. We further discuss accidental symmetries and other dynamical features stemming from the new strongly interacting scalars. If the same phenomenology can be obtained from models without our elementary scalars, they would reappear as composite states.

  17. Fundamental partial compositeness

    International Nuclear Information System (INIS)

    Sannino, Francesco; Strumia, Alessandro; Tesi, Andrea; Vigiani, Elena

    2016-01-01

    We construct renormalizable Standard Model extensions, valid up to the Planck scale, that give a composite Higgs from a new fundamental strong force acting on fermions and scalars. Yukawa interactions of these particles with Standard Model fermions realize the partial compositeness scenario. Under certain assumptions on the dynamics of the scalars, successful models exist because gauge quantum numbers of Standard Model fermions admit a minimal enough ‘square root’. Furthermore, right-handed SM fermions have an SU(2)_R-like structure, yielding a custodially-protected composite Higgs. Baryon and lepton numbers arise accidentally. Standard Model fermions acquire mass at tree level, while the Higgs potential and flavor violations are generated by quantum corrections. We further discuss accidental symmetries and other dynamical features stemming from the new strongly interacting scalars. If the same phenomenology can be obtained from models without our elementary scalars, they would reappear as composite states.

  18. Partial oxidation process

    International Nuclear Information System (INIS)

    Najjar, M.S.

    1987-01-01

    A process is described for the production of gaseous mixtures comprising H/sub 2/+CO by the partial oxidation of a fuel feedstock comprising a heavy liquid hydrocarbonaceous fuel having a nickel, iron, and vanadium-containing ash or petroleum coke having a nickel, iron, and vanadium-containing ash, or mixtures thereof. The feedstock includes a minimum of 0.5 wt. % of sulfur and the ash includes a minimum of 5.0 wt. % vanadium, a minimum of 0.5 ppm nickel, and a minimum of 0.5 ppm iron. The process comprises: (1) mixing together a copper-containing additive with the fuel feedstock; wherein the weight ratio of copper-containing additive to ash in the fuel feedstock is in the range of about 1.0-10.0, and there is at least 10 parts by weight of copper for each part by weight of vanadium; (2) reacting the mixture from (1) at a temperature in the range of 2200 0 F to 2900 0 F and a pressure in the range of about 5 to 250 atmospheres in a free-flow refactory lined partial oxidation reaction zone with a free-oxygen containing gas in the presence of a temperature moderator and in a reducing atmosphere to produce a hot raw effluent gas stream comprising H/sub 2/+CO and entrained molten slag; and where in the reaction zone and the copper-containing additive combines with at least a portion of the nickel and iron constituents and sulfur found in the feedstock to produce a liquid phase washing agent that collects and transports at least a portion of the vanadium-containing oxide laths and spinels and other ash components and refractory out of the reaction zone; and (3) separating nongaseous materials from the hot raw effluent gas stream

  19. The Uncanny Valley and Nonverbal Communication in Virtual Characters

    DEFF Research Database (Denmark)

    Tinwell, Angela; Grimshaw, Mark Nicholas; Abdel Nabi, Debbie

    2014-01-01

    This chapter provides an overview of a current research project investigating the Uncanny Valley phenomenon in realistic, human-like virtual characters. !e research methods used in this Work include a retrospective of both empirical studies and philosophical writings on the Uncanny. No other...... research has explored the notion that realistic, human-like, virtual characters are regarded less favorably due to a perceived diminished degree of responsiveness in facial expression, specifically, nonverbal communication (NVC) in the upper face region. So far, this research project has provided the first...... empirical evidence to test the Uncanny Valley phenomenon in the domain of animated video game characters with speech, as opposed to just still, unresponsive images, as used in previous studies. Based on the results of these experiments, a conceptual framework of the Uncanny Valley in virtual characters has...

  20. Variability and Character Association in F2 Segregating Population ...

    African Journals Online (AJOL)

    Michael Horsfall

    Department of Genetics and Plant Breeding, 1Department of Horticulture. Bangabandhu Sheikh Mujibur Rahman Agricultural University. Gazipur 1706, Bangladesh. ABSTRACT: The F2 segregating generations of exotic tomato hybrids were studied to measure variability, character association and path coefficient analysis.

  1. Perceiving and experiencing fictional characters: an integrative account

    NARCIS (Netherlands)

    Hoorn, J.F.; Konijn, E.A.

    2003-01-01

    Fictional characters (PCs) and mediated persons in literature, theater, film, art, TV, and digital media fulfill basic psychological functions, although the processes involved remain unspecified. Departing from identification and empathy hypotheses, a new context-sensitive model draws upon

  2. Portrayal of Women Characters in Selected Contemporary Yoruba ...

    African Journals Online (AJOL)

    Nekky Umera

    women as loving, hardworking, serious-minded and people of dignity and character. ... all the mental or moral qualities that make a person, group, ..... friends' and neighbours' wives. .... So also, money influence and entice women to engage.

  3. Variation in quantitative characters of faba bean after seed ...

    African Journals Online (AJOL)

    Variation in quantitative characters of faba bean after seed irradiation and associated molecular changes. Sonia Mejri, Yassine Mabrouk, Marie Voisin, Philippe Delavault, Philippe Simier, Mouldi Saidi, Omrane Belhadj ...

  4. Two-tier architecture for unconstrained handwritten character ...

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    This approach uses the Kohonen self-organizing neural network for data classification in the ... Traditional classifiers test the ..... Trier O D, Jain A K, Taxt T 1996 Feature extraction methods for character recognition – A survey. Pattern Recogn.

  5. Evolution of specialization and ecological character displacement: metabolic plasticity matters.

    NARCIS (Netherlands)

    Egas, C.J.M.; Reydon, Th.A.C.; Hemerik, L.

    2005-01-01

    An important question in evolutionary biology, especially with respect to herbivorous arthropods, is the evolution of specialization. In a previous paper, the combined evolutionary dynamics of specialization and ecological character displacement was studied, focusing on the role of herbivore

  6. Feminism and Self-Assessertion of Female Characters in Buchi ...

    African Journals Online (AJOL)

    Feminism and Self-Assessertion of Female Characters in Buchi Emecheta's Second ... and ideological frame work it directly opposes sexism by supporting gender ... stereotype of women, whereby women are seen as helpless, dependent and ...

  7. Dirichlet Characters, Gauss Sums, and Inverse Z Transform

    OpenAIRE

    Gao, Jing; Liu, Huaning

    2012-01-01

    A generalized Möbius transform is presented. It is based on Dirichlet characters. A general algorithm is developed to compute the inverse $Z$ transform on the unit circle, and an error estimate is given for the truncated series representation.

  8. 8 CFR 316.10 - Good moral character.

    Science.gov (United States)

    2010-01-01

    ... was not a single offense for simple possession of 30 grams or less of marijuana; (iv) Admits...) Proof of good moral character in certain cases—(1) Effect of probation or parole. An applicant who has...

  9. Young James Madison: His Character and Civic Values.

    Science.gov (United States)

    Bennett, William J.

    1987-01-01

    Examines the life of James Madison, Founding Father and "theoretic statesman." Focuses specifically on Madison's education and character, his friendship with Thomas Jefferson, and his civic legacy: a selfless devotion to republican government and union. (JDH)

  10. Aggression in Sport: Its Implications for Character Building.

    Science.gov (United States)

    VanDyke, Roger R.

    1980-01-01

    The premise that "sports builds character" is scrutinized through a discussion of several contact sports--boxing, hockey, and football. The fine line between assertiveness and aggression is explored, and the interrelationship between society and sports is investigated. (JN)

  11. Beyond the Story Map: Inferential Comprehension via Character Perspective

    Science.gov (United States)

    McTigue, Erin; Douglass, April; Wright, Katherine L.; Hodges, Tracey S.; Franks, Amanda D.

    2015-01-01

    Inferential comprehension requires both emotional intelligence and cognitive skills, however instructional comprehension strategies typically underemphasize the emotional contribution. This article documents an intervention used by diverse third grade students which centers on teaching story comprehension through character perspective-taking…

  12. The tragicomic realisation of life and destiny of Kocic's characters

    Directory of Open Access Journals (Sweden)

    Soleša Biljana S.

    2016-01-01

    Full Text Available This paper discusses the collective identity of the characters of Kocic's prose. It examines the archetypal traits, oddify, originality and impressiveness of these unique characters in Serbian literature as well as the presence of collective memory, the awareness of one self and the others, historical, social and economic circumstances that surround Kocic's heroes. Looking back at the elements of the creative process, the artist's motivation and the presence of the tragical and the comical can be singled out. The characters of Simeun Djak, David Strbac, Mracajski prota, Relja Knezevic have been analyzed, and a short review of the female characters is given. Revealing the extent to which the creativity of Petar Kocic coincides with the elements of history, psychology, sociology and anthropogeography, a literary-scientific thought on his work gets completed and the versality to approach to the reading is allowed.

  13. Temperament and character as endophenotype in adults with autism spectrum disorders or attention deficit/hyperactivity disorder.

    Science.gov (United States)

    Sizoo, Bram B; van der Gaag, Rutger Jan; van den Brink, Wim

    2015-05-01

    Autism spectrum disorder and attention deficit/hyperactivity disorder overlap in several ways, raising questions about the nature of this comorbidity. Rommelse et al. published an innovative review of candidate endophenotypes for autism spectrum disorder and attention deficit/hyperactivity disorder in cognitive and brain domains. They found that all the endophenotypic impairments that were reviewed in attention deficit/hyperactivity disorder were also present in autism spectrum disorder, suggesting a continuity model with attention deficit/hyperactivity disorder as "a light form of autism spectrum disorder." Using existing data, 75 adults with autism spectrum disorder and 53 with attention deficit/hyperactivity disorder were directly compared on autistic symptoms with the autism spectrum quotient, and on the endophenotypic measure of temperament and character, using the Abbreviated (Dutch: Verkorte) Temperament and Character Inventory. Based on the hypothesis that attention deficit/hyperactivity disorder and autism spectrum disorder are disorders on a continuous spectrum, autism spectrum quotient scores and abbreviated Temperament and Character Inventory scores were expected to be different from normal controls in both disorders in a similar direction. In addition, the autism spectrum quotient and abbreviated Temperament and Character Inventory scores were expected to be closely correlated. These conditions applied to only two of the seven Abbreviated Temperament and Character Inventory scales (harm avoidance and self-directedness), suggesting that temperament and character as an endophenotype of autism spectrum disorder and attention deficit/hyperactivity disorder provides only partial support for the continuity hypothesis of autism spectrum disorder and attention deficit/hyperactivity disorder. © The Author(s) 2014.

  14. Covalent attachment of antagonists to the a7 nicotinic acetylcholine receptor: synthesis and reactivity of substituted maleimides

    DEFF Research Database (Denmark)

    Ambrus, Joseph I; Halliday, Jill I; Kanizaj, Nicholas

    2012-01-01

    The 3-methylmaleimide congeners of the natural product methyllycaconitine (MLA) and an analogue covalently attach to functional cysteine mutants of the a7 nicotinic acetylcholine receptor (nAChR).......The 3-methylmaleimide congeners of the natural product methyllycaconitine (MLA) and an analogue covalently attach to functional cysteine mutants of the a7 nicotinic acetylcholine receptor (nAChR)....

  15. Combination of supramolecular cross-linking with covalent cross-linking through epoxide ring-opening including gel studies

    NARCIS (Netherlands)

    Hofmeier, H.; El-Ghayoury, A.; Schubert, U.S.

    2003-01-01

    Terpolymers based on poly(methyl methacrylate), containing terpyridine-moieties as well as epoxide groups, were synthesized via free-radical polymeri-zation. The products were cross-linked non-covalently with iron(II) ions and cova-lently by treatment with AlCl3. Both steps could be combined in

  16. Combination of supramolecular cross-linking with covalent cross-linking through epoxide ring-opening including gel studies

    NARCIS (Netherlands)

    Hofmeier, H.; El-Ghayoury, A.; Schubert, U.S.

    2003-01-01

    Terpolymers based on poly(methyl methacrylate), containing terpyridinemoieties as well as epoxide groups, were synthesized via free-radical polymerization. The products were cross-linked non-covalently with iron(II) ions and covalently by treatment with AlCl3. Both steps could be combined in

  17. Character, Social-Emotional, and Academic Outcomes among Underachieving Elementary School Students

    Science.gov (United States)

    Grier, Leslie K.

    2012-01-01

    One purpose of this research was to examine the psychometric properties of a character assessment scale (the Character Assessment for School Age Children; CASAC) based on 6 pillars of character (Josephson Institute, 2009). Many youth development and character education programs utilize some, if not all, of the pillars of character explicitly or…

  18. The Proximate Unit in Chinese Handwritten Character Production

    Directory of Open Access Journals (Sweden)

    Jenn-Yeu eChen

    2013-08-01

    Full Text Available In spoken word production, a proximate unit is the first phonological unit at the sublexical level that is selectable for production (O’Seaghdha, Chen, & Chen, 2010. The present study investigated whether the proximate unit in Chinese handwritten word production is the stroke, the radical, or something in between. A written version of the form preparation task was adopted. Chinese participants learned sets of two-character words, later were cued with the first character of each word, and had to write down the second character (the target. Response times were measured from the onset of a cue character to the onset of a written response. In Experiment 1, the target characters within a block shared (homogeneous or did not share (heterogeneous the first stroke. In Experiment 2, the first two strokes were shared in the homogeneous blocks. Response times in the homogeneous blocks and in the heterogeneous blocks were comparable in both experiments (Exp. 1: 687 ms vs. 684 ms, Exp. 2: 717 vs. 716. In Experiment 3 and 4, the target characters within a block shared or did not share the first radical. Response times in the homogeneous blocks were significantly faster than those in the heterogeneous blocks (Exp. 3: 685 vs. 704, Exp. 4: 594 vs. 650. In Experiment 5 and 6, the shared component was a Gestalt-like form that is more than a stroke, constitutes a portion of the target character, can be a stand-alone character itself, can be a radical of another character but is not a radical of the target character (e.g., 士in聲, 鼓, 穀, 款; called a logographeme. Response times in the homogeneous blocks were significantly faster than those in the heterogeneous blocks (Exp. 5: 576 vs. 625, Exp. 6: 586 vs. 620. These results suggest a model of Chinese handwritten character production in which the stroke is not a functional unit, the radical plays the role of a morpheme, and the logographeme is the proximate unit.

  19. Novel covalently linked insulin dimer engineered to investigate the function of insulin dimerization.

    Directory of Open Access Journals (Sweden)

    Tine N Vinther

    Full Text Available An ingenious system evolved to facilitate insulin binding to the insulin receptor as a monomer and at the same time ensure sufficient stability of insulin during storage. Insulin dimer is the cornerstone of this system. Insulin dimer is relatively weak, which ensures dissociation into monomers in the circulation, and it is stabilized by hexamer formation in the presence of zinc ions during storage in the pancreatic β-cell. Due to the transient nature of insulin dimer, direct investigation of this important form is inherently difficult. To address the relationship between insulin oligomerization and insulin stability and function, we engineered a covalently linked insulin dimer in which two monomers were linked by a disulfide bond. The structure of this covalent dimer was identical to the self-association dimer of human insulin. Importantly, this covalent dimer was capable of further oligomerization to form the structural equivalent of the classical hexamer. The covalently linked dimer neither bound to the insulin receptor, nor induced a metabolic response in vitro. However, it was extremely thermodynamically stable and did not form amyloid fibrils when subjected to mechanical stress, underlining the importance of oligomerization for insulin stability.

  20. Immobilization of β-glucosidase onto mesoporous silica support: Physical adsorption and covalent binding of enzyme

    Directory of Open Access Journals (Sweden)

    Ivetić Darjana Ž.

    2014-01-01

    Full Text Available This paper investigates β-glucosidase immobilization onto mesoporous silica support by physical adsorption and covalent binding. The immobilization was carried out onto micro-size silica aggregates with the average pore size of 29 nm. During physical adsorption the highest yield of immobilized β-glucosidase was obtained at initial protein concentration of 0.9 mg ml-1. Addition of NaCl increased 1.7-fold, while Triton X-100 addition decreased 6-fold yield of adsorption in comparison to the one obtained without any addition. Covalently bonded β-glucosidase, via glutaraldehyde previously bonded to silanized silica, had higher yield of immobilized enzyme as well as higher activity and substrate affinity in comparison to the one physically adsorbed. Covalent binding did not considerably changed pH and temperature stability of obtained biocatalyst in range of values that are commonly used in reactions in comparison to unbounded enzyme. Furthermore, covalent binding provided biocatalyst which retained over 70% of its activity after 10 cycles of reuse. [Projekat Ministarstva nauke Republike Srbije, br. III 45021

  1. Mechanisms for Covalent Immobilization of Horseradish Peroxidase on Ion-Beam-Treated Polyethylene

    Directory of Open Access Journals (Sweden)

    Alexey V. Kondyurin

    2012-01-01

    Full Text Available The surface of polyethylene was modified by plasma immersion ion implantation. Structure changes including carbonization and oxidation were observed. High surface energy of the modified polyethylene was attributed to the presence of free radicals on the surface. The surface energy decay with storage time after treatment was explained by a decay of the free radical concentration while the concentration of oxygen-containing groups increased with storage time. Horseradish peroxidase was covalently attached onto the modified surface by the reaction with free radicals. Appropriate blocking agents can block this reaction. All aminoacid residues can take part in the covalent attachment process, providing a universal mechanism of attachment for all proteins. The native conformation of attached protein is retained due to hydrophilic interactions in the interface region. The enzymatic activity of covalently attached protein remained high. The long-term activity of the modified layer to attach protein is explained by stabilisation of unpaired electrons in sp2 carbon structures. A high concentration of free radicals can give multiple covalent bonds to the protein molecule and destroy the native conformation and with it the catalytic activity. The universal mechanism of protein attachment to free radicals could be extended to various methods of radiation damage of polymers.

  2. Protein tetrazinylation via diazonium coupling for covalent and catalyst-free bioconjugation.

    Science.gov (United States)

    Zhang, Jie; Men, Yuwen; Lv, Shanshan; Yi, Long; Chen, Jian-Feng

    2015-12-21

    An efficient and bench-stable reagent was synthesized for direct and covalent introduction of tetrazines onto target protein or virus surfaces, which can be further modified based on tetrazine-ene ligation to achieve fluorescence labelling or PEGylation under mild conditions.

  3. Covalent immobilization of redox protein within the mesopores of transparent conducting electrodes

    Czech Academy of Sciences Publication Activity Database

    Müller, V.; Rathouský, Jiří; Fattakhova-Rohlfing, D.

    2014-01-01

    Roč. 116, JAN 2014 (2014), s. 1-8 ISSN 0013-4686 R&D Projects: GA ČR GA104/08/0435 Institutional support: RVO:61388955 Keywords : Covalent immobilization * Porous electrodes * Redox proteins Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 4.504, year: 2014

  4. Recent advances in covalent, site-specific protein immobilization [version 1; referees

    DEFF Research Database (Denmark)

    Meldal, Morten Peter; Schoffelen, Sanne

    2016-01-01

    The properties of biosensors, biomedical implants, and other materials based on immobilized proteins greatly depend on the method employed to couple the protein molecules to their solid support. Covalent, site-specific immobilization strategies are robust and can provide the level of control...

  5. Identification of target cells by immunohistochemical detection of covalently rearranged estradiol in rehydrated paraffin sections.

    Science.gov (United States)

    Jungblut, P W; Sierralta, W D

    1998-04-01

    Estradiol is released from the binding niche of the receptor and covalently arrested in the molecular vicinity by the Mannich reaction during target fixation in acetic acid/formaldehyde. The exposed steroid is freely accessible for appropriate antibodies. It can be visualized in sections by the second antibody/enzyme technique in high resolution and without enhancements.

  6. Covalent functionalization of graphene oxide with polyglycerol and their use as templates for anchoring magnetic nanoparticles

    NARCIS (Netherlands)

    Pham, Tuan Anh; Kumar, Nanjundan Ashok; Jeong, Yeon Tae

    An efficient strategy for the preparation of water-dispersible hybrid material containing graphene oxide and polyglycerol for the first time is demonstrated. Pristine graphite was firstly oxidized to obtain graphene oxide with hydroxyl functional groups. Then, the covalent grafting of polyglycerol

  7. Direct covalent coupling of proteins to nanostructured plasma polymers: a route to tunable cell adhesion

    Czech Academy of Sciences Publication Activity Database

    Melnichuk, I.; Choukourov, A.; Bilek, M.; Weiss, A.; Vandrovcová, Marta; Bačáková, Lucie; Hanuš, J.; Kousal, J.; Shelemin, A.; Solař, P.; Slavínská, D.; Biederman, H.

    2015-01-01

    Roč. 351, Oct 1 (2015), s. 537-545 ISSN 0169-4332 R&D Projects: GA MZd(CZ) NT13297 Institutional support: RVO:67985823 Keywords : covalent binding * plasma polymers * MG-63 osteoblasts Subject RIV: CD - Macromolecular Chemistry Impact factor: 3.150, year: 2015

  8. Formation of Me–O–Si covalent bonds at the interface between polysilazane and stainless steel

    Energy Technology Data Exchange (ETDEWEB)

    Amouzou, Dodji, E-mail: adodji@gmail.com [Research Centre in Physics of Matter and Radiation (PMR), University of Namur, Rue de Bruxelles 61, 5000 Namur (Belgium); Fourdrinier, Lionel; Maseri, Fabrizio [CRM-Group, Boulevard de Colonster, B 57, 4000 Liège (Belgium); Sporken, Robert [Research Centre in Physics of Matter and Radiation (PMR), University of Namur, Rue de Bruxelles 61, 5000 Namur (Belgium)

    2014-11-30

    Highlights: • Natural metal-oxides, hydroxides are detected on the top surface of steel substrates we tested. • Polysilazane reacts with hydroxide functional groups on steel substrates to form Cr–O–Si and Fe–O–Si covalent bonds. • Covalent bonding between steel and polysilazane at the interface was probed using spectroscopic techniques. - Abstract: In earlier works, we demonstrated the potential of polysilazane (PSZ) coatings for a use as insulating layers in Cu(In,Ga)Se{sub 2} (CIGS) solar cells prepared on steels substrates and showed a good adhesion between PSZ coatings and both AISI316 and AISI430 steels. In the present paper, spectroscopic techniques are used to elucidate the reason of such adhesion. X-ray Photoelectron Spectroscopy (XPS) was used to investigate surfaces for the two steel substrates and showed the presence of metal oxides and metal hydroxides at the top surface. XPS has been also used to probe interfaces between substrates and PSZ, and metallosiloxane (Me–O–Si) covalent bonds have been detected. These results were confirmed by Infra-Red Reflection Absorption Spectroscopy (IRRAS) analyses since vibrations related to Cr–O–Si and Fe–O–Si compounds were detected. Thus, the good adhesion between steel substrates and PSZ coatings was explained by covalent bonding through chemical reactions between PSZ precursors and hydroxide functional groups present on top surface of the two types of steel. Based on these results, an adhesion mechanism between steel substrates and PSZ coatings is proposed.

  9. Gel Electrolytes of Covalent Network Polybenzimidazole and Phosphoric Acid by Direct Casting

    DEFF Research Database (Denmark)

    Kirkebæk, Andreas; Aili, David; Henkensmeier, Dirk

    2017-01-01

    for preparing mechanically robust covalent network polybenzimidazole membranes containing up to 95 wt% phosphoric acid. Diamino-terminal pre-polymers of different chain lengths are first prepared, followed by addition of a trifunctional carboxylic acid. The crude solutions are cast and subsequently heat treated...

  10. A chiroptical switch based on supramolecular chirality transfer through alkyl chain entanglement and dynamic covalent bonding.

    Science.gov (United States)

    Lv, Kai; Qin, Long; Wang, Xiufeng; Zhang, Li; Liu, Minghua

    2013-12-14

    Chirality transfer is an interesting phenomenon in Nature, which represents an important step to understand the evolution of chiral bias and the amplification of the chirality. In this paper, we report the chirality transfer via the entanglement of the alkyl chains between chiral gelator molecules and achiral amphiphilic Schiff base. We have found that although an achiral Schiff base amphiphile could not form organogels in any kind of organic solvents, it formed co-organogels when mixed with a chiral gelator molecule. Interestingly, the chirality of the gelator molecules was transferred to the Schiff base chromophore in the mixed co-gels and there was a maximum mixing ratio for the chirality transfer. Furthermore, the supramolecular chirality was also produced based on a dynamic covalent chemistry of an imine formed by the reaction between an aldehyde and an amine. Such a covalent bond of imine was formed reversibly depending on the pH variation. When the covalent bond was formed the chirality transfer occurred, when it was destroyed, the transfer stopped. Thus, a supramolecular chiroptical switch is obtained based on supramolecular chirality transfer and dynamic covalent chemistry.

  11. Metal–organic covalent network chemical vapor deposition for gas separation

    NARCIS (Netherlands)

    Boscher, N.D.; Wang, M.; Perrotta, A.; Heinze, K.; Creatore, A.; Gleason, K.K.

    2016-01-01

    The chemical vapor deposition (CVD) polymerization of metalloporphyrin building units is demonstrated to provide an easily up-scalable one-step method toward the deposition of a new class of dense and defect-free metal–organic covalent network (MOCN) layers. The resulting hyper-thin and flexible

  12. Covalent binding of organophosphorothioates to albumin: A new perspective for OP-pesticide biomonitoring?

    NARCIS (Netherlands)

    Noort, D.; Hulst, A.G.; Zuylen, A. van; Rijssel, E. van; Schans, M.J. van der

    2009-01-01

    We here report on the covalent binding of various organophosphorothioate (OPT) pesticides to albumin at in vitro exposure levels that did not give rise to butyrylcholinesterase inhibition. Adduct formation occurred at the Tyr-411 residue of albumin, as was firmly corroborated by LC-tandem MS

  13. Stabilization of 5A1 urease by covalent attachement to wool | Ahmed ...

    African Journals Online (AJOL)

    The investigation of five bacterial strains for urease production referred that Bacillus licheniformis 5A1 had the highest urease activity (10.3U/ml/min) after 24h. The enzyme was covalently coupled to different carriers via glutaraldehyde, and wool gave the highest immobilization yield (76.4%) and retained 85% of the original ...

  14. Origin of the Distinct Diffusion Behaviors of Cu and Ag in Covalent and Ionic Semiconductors.

    Science.gov (United States)

    Deng, Hui-Xiong; Luo, Jun-Wei; Li, Shu-Shen; Wei, Su-Huai

    2016-10-14

    It is well known that Cu diffuses faster than Ag in covalent semiconductors such as Si, which has prevented the replacement of Ag by Cu as a contact material in Si solar cells for reducing the cost. Surprisingly, in more ionic materials such as CdTe, Ag diffuses faster than Cu despite that it is larger than Cu, which has prevented the replacement of Cu by Ag in CdTe solar cells to improve the performance. But, so far, the mechanisms behind these distinct diffusion behaviors of Cu and Ag in covalent and ionic semiconductors have not been addressed. Here we reveal the underlying mechanisms by combining the first-principles calculations and group theory analysis. We find that the symmetry controlled s-d coupling plays a critical role in determining the diffusion behaviors. The s-d coupling is absent in pure covalent semiconductors but increases with the ionicity of the zinc blende semiconductors, and is larger for Cu than for Ag, owing to its higher d orbital energy. In conjunction with Coulomb interaction and strain energy, the s-d coupling is able to explain all the diffusion behaviors from Cu to Ag and from covalent to ionic hosts. This in-depth understanding enables us to engineer the diffusion of impurities in various semiconductors.

  15. Discovery of covalent inhibitors for MIF tautomerase via cocrystal structures with phantom hits from virtual screening

    Energy Technology Data Exchange (ETDEWEB)

    McLean, Larry R.; Zhang, Ying; Li, Hua; Li, Ziyu; Lukasczyk, Ulrike; Choi, Yong-Mi; Han, Zuoning; Prisco, Joy; Fordham, Jeremy; Tsay, Joseph T.; Reiling, Stephan; Vaz, Roy J.; Li, Yi; (Sanofi)

    2010-10-28

    Biochemical and X-ray crystallographic studies confirmed that hydroxyquinoline derivatives identified by virtual screening were actually covalent inhibitors of the MIF tautomerase. Adducts were formed by N-alkylation of the Pro-1 at the catalytic site with a loss of an amino group of the inhibitor.

  16. Dynamic covalent chemistry of bisimines at the solid/liquid interface monitored by scanning tunnelling microscopy.

    Science.gov (United States)

    Ciesielski, Artur; El Garah, Mohamed; Haar, Sébastien; Kovaříček, Petr; Lehn, Jean-Marie; Samorì, Paolo

    2014-11-01

    Dynamic covalent chemistry relies on the formation of reversible covalent bonds under thermodynamic control to generate dynamic combinatorial libraries. It provides access to numerous types of complex functional architectures, and thereby targets several technologically relevant applications, such as in drug discovery, (bio)sensing and dynamic materials. In liquid media it was proved that by taking advantage of the reversible nature of the bond formation it is possible to combine the error-correction capacity of supramolecular chemistry with the robustness of covalent bonding to generate adaptive systems. Here we show that double imine formation between 4-(hexadecyloxy)benzaldehyde and different α,ω-diamines as well as reversible bistransimination reactions can be achieved at the solid/liquid interface, as monitored on the submolecular scale by in situ scanning tunnelling microscopy imaging. Our modular approach enables the structurally controlled reversible incorporation of various molecular components to form sophisticated covalent architectures, which opens up perspectives towards responsive multicomponent two-dimensional materials and devices.

  17. Regio- and Stereospecific Conversion of 4-Alkylphenols by the Covalent Flavoprotein Vanillyl-Alcohol Oxidase

    NARCIS (Netherlands)

    Heuvel, Robert H.H. van den; Fraaije, Marco W.; Laane, Colja; Berkel, Willem J.H. van

    1998-01-01

    The regio- and stereospecific conversion of prochiral 4-alkylphenols by the covalent flavoprotein vanillyl-alcohol oxidase was investigated. The enzyme was active, with 4-alkylphenols bearing aliphatic side chains of up to seven carbon atoms. Optimal catalytic efficiency occurred with 4-ethylphenol

  18. The yeast cell fusion protein Prm1p requires covalent dimerization to promote membrane fusion.

    Directory of Open Access Journals (Sweden)

    Alex Engel

    2010-05-01

    Full Text Available Prm1p is a multipass membrane protein that promotes plasma membrane fusion during yeast mating. The mechanism by which Prm1p and other putative regulators of developmentally controlled cell-cell fusion events facilitate membrane fusion has remained largely elusive. Here, we report that Prm1p forms covalently linked homodimers. Covalent Prm1p dimer formation occurs via intermolecular disulfide bonds of two cysteines, Cys-120 and Cys-545. PRM1 mutants in which these cysteines have been substituted are fusion defective. These PRM1 mutants are normally expressed, retain homotypic interaction and can traffic to the fusion zone. Because prm1-C120S and prm1-C545S mutants can form covalent dimers when coexpressed with wild-type PRM1, an intermolecular C120-C545 disulfide linkage is inferred. Cys-120 is adjacent to a highly conserved hydrophobic domain. Mutation of a charged residue within this hydrophobic domain abrogates formation of covalent dimers, trafficking to the fusion zone, and fusion-promoting activity. The importance of intermolecular disulfide bonding informs models regarding the mechanism of Prm1-mediated cell-cell fusion.

  19. COVALENTLY ATTACHED MULTILAYER ULTRA-THIN FILMS FROM DIAZORESIN AND CALIXARENES

    Institute of Scientific and Technical Information of China (English)

    Zhao-hui Yang; Wei-xiao Cao

    2003-01-01

    A kind of photosensitive ultra-thin film was fabricated from diazoresin (DR) and various calixarenes by using the self-assembly technique. Under UV irradiation both the ionic- and hydrogen bonds between the layers of the film will convert into covalent bonds. As a result, the stability of the film toward polar solvents increases dramatically.

  20. Covalent Bonding of Chlorogenic Acid Induces Structural Modifications on Sunflower Proteins

    NARCIS (Netherlands)

    Karefyllakis, D.; Salakou, Stavroula; Bitter, J.H.; Goot, van der A.J.; Nikiforidis, K.

    2018-01-01

    Proteins and phenols coexist in the confined space of plant cells leading to reactions between them, which result in new covalently bonded complex molecules. This kind of reactions has been widely observed during storage and processing of plant materials. However, the nature of the new complex

  1. Molecular-dynamics simulation of crystalline 18-crown-6: thermal shortening of covalent bonds

    NARCIS (Netherlands)

    van Eerden, J.; Harkema, Sybolt; Feil, D.

    1990-01-01

    Molecular-dynamics simulations of crystalline 18-crown-6 have been performed in a study of the apparent thermal shortening of covalent bonds observed in crystal structures. At 100 K, a shortening of 0.006 _+ 0.001 A for C----C and C----O bonds was obtained. This result was found to be independent of

  2. A simple approach for immobilization of gold nanoparticles on graphene oxide sheets by covalent bonding

    NARCIS (Netherlands)

    Pham, Tuan Anh; Choi, Byung Choon; Lim, Kwon Taek; Jeong, Yeon Tae

    2011-01-01

    Amino - functionalized gold nanoparticles with a diameter of around 5 nm were immobilized onto the surface of graphene oxide sheets (GOS) by covalent bonding through a simple amidation reaction. Pristine graphite was firstly oxidized and exfoliated to obtain GOS, which further were acylated with

  3. 共价键的离子化%Ionization of Covalent Bond

    Institute of Scientific and Technical Information of China (English)

    王稼国; 荆西平

    2017-01-01

    本文用化学键理论分析和推导了共价键离子化的几种方式,包括金属和非金属单质中共价键的诱导离子化、化合物中共价键的降温和自诱导离子化以及含氢化合物和金属化合物的诱导离子化.从能量角度分析了离子化趋势的规律性,并且讨论了共价键的离子化的一些重要应用.%Several ionization patterns of covalent bond,including induced-ionization of covalent bond in metals and nonmetals,induced-ionization of covalent bond in hydrogen compounds and metal compounds,lowering temperature and self-induced ionization of compound,and so on,were dedueed and analyzed by using chemical bond theory.The trend of ionization was also analyzed on energy changing and several important applications of the ionization of covalent bond were discussed.

  4. Ultrafast cooling by covalently bonded graphene-carbon nanotube hybrid immersed in water

    DEFF Research Database (Denmark)

    Chen, Jie; Walther, Jens Honore; Koumoutsakos, Petros

    2016-01-01

    , we demonstrate, through transient heat-dissipation simulations, that a covalently bonded graphene-carbon nanotube (G-CNT) hybrid immersed in water is a promising solution for the ultrafast cooling of such high-temperature and high heat-flux surfaces. The G-CNT hybrid offers a unique platform...

  5. Nano-Sized Zero Valent Iron and Covalent Organic Polymer Composites for Azo Dye Remediation

    DEFF Research Database (Denmark)

    Mines, Paul D.; Byun, Jeehye; Hwang, Yuhoon

    2014-01-01

    . In this study, the effect of various covalent organic polymers (COPs) as effective supporting materials for nZVI for optimal pollutant degradation was assessed. These COPs demonstrate promising results for the ability to adsorb and remove carbon dioxide, yielding the notion that they are capable of groundwater...... in chlorinated organics, heavy metals, and various other groundwater contaminants....

  6. Catalyst recycling via specific non-covalent adsorption on modified silicas

    NARCIS (Netherlands)

    Kluwer, A.M.; Simons, C.; Knijnenburg, Q.; van der Vlugt, J.I.; de Bruin, B.; Reek, J.N.H.

    2013-01-01

    This article describes a new strategy for the recycling of a homogeneous hydroformylation catalyst, by selective adsorption of the catalyst to tailor-made supports after a batchwise reaction. The separation of the catalyst from the product mixture is based on selective non-covalent supramolecular

  7. Covalent binding of nitrogen mustards to the cysteine-34 residue in human serum albumin

    NARCIS (Netherlands)

    Noort, D.; Hulst, A.G.; Jansen, R.

    2002-01-01

    Covalent binding of various clinically important nitrogen mustards to the cysteine-34 residue of human serum albumin, in vitro and in vivo, is demonstrated. A rapid method for detection of these adducts is presented, based on liquid chromatography-tandem mass spectrometry analysis of the adducted

  8. Nature and consequences of non-covalent interactions between flavonoids and macronutrients in foods.

    Science.gov (United States)

    Bordenave, Nicolas; Hamaker, Bruce R; Ferruzzi, Mario G

    2014-01-01

    Many of the potential health benefits of flavonoids have been associated with their specific chemical and biological properties including their ability to interact and bind non-covalently to macronutrients in foods. While flavonoid-protein interactions and binding have been the subject of intensive study, significantly less is understood about non-covalent interactions with carbohydrates and lipids. These interactions with macronutrients are likely to impact both the flavonoid properties in foods, such as their radical scavenging activity, and the food or beverage matrix itself, including their taste, texture and other sensorial properties. Overall, non-covalent binding of flavonoids with macronutrients is primarily driven by van der Waals interactions. From the flavonoid perspective, these interactions are modulated by characteristics such as degree of polymerization, molecular flexibility, number of external hydroxyl groups, or number of terminal galloyl groups. From the macronutrient standpoint, electrostatic and ionic interactions are generally predominant with carbohydrates, while hydrophobic interactions are generally predominant with lipids and mainly limited to interactions with flavonols. All of these interactions are involved in flavonoid-protein interactions. While primarily associated with undesirable characteristics in foods and beverages, such as astringency, negative impact on macronutrient digestibility and hazing, more recent efforts have attempted to leverage these interactions to develop controlled delivery systems or strategies to enhance flavonoids bioavailability. This paper aims at reviewing the fundamental bases for non-covalent interactions, their occurrence in food and beverage systems and their impact on the physico-chemical, organoleptic and some nutritional properties of food.

  9. Improved Performance of Pseudomonas fluorescens lipase by covalent immobilization onto Amberzyme

    NARCIS (Netherlands)

    Aslan, Yakup; Handayani, Nurrahmi; Stavila, Erythrina; Loos, Katja

    2013-01-01

    Objective: In this study, the conditions of covalent immobilization of Pseudomonas fluorescens lipase onto an oxirane-activated support (Amberzyme) were optimized to obtain a high activity yield. Furthermore, the operational and storage stabilities of immobilized lipase were tested. Methods: Optimum

  10. Inorganic Materials as Supports for Covalent Enzyme Immobilization: Methods and Mechanisms

    Directory of Open Access Journals (Sweden)

    Paolo Zucca

    2014-09-01

    Full Text Available Several inorganic materials are potentially suitable for enzymatic covalent immobilization, by means of several different techniques. Such materials must meet stringent criteria to be suitable as solid matrices: complete insolubility in water, reasonable mechanical strength and chemical resistance under the operational conditions, the capability to form manageable particles with high surface area, reactivity towards derivatizing/functionalizing agents. Non-specific protein adsorption should be always considered when planning covalent immobilization on inorganic solids. A huge mass of experimental work has shown that silica, silicates, borosilicates and aluminosilicates, alumina, titania, and other oxides, are the materials of choice when attempting enzyme immobilizations on inorganic supports. More recently, some forms of elemental carbon, silicon, and certain metals have been also proposed for certain applications. With regard to the derivatization/functionalization techniques, the use of organosilanes through silanization is undoubtedly the most studied and the most applied, although inorganic bridge formation and acylation with selected acyl halides have been deeply studied. In the present article, the most common inorganic supports for covalent immobilization of the enzymes are reviewed, with particular focus on their advantages and disadvantages in terms of enzyme loadings, operational stability, undesired adsorption, and costs. Mechanisms and methods for covalent immobilization are also discussed, focusing on the most widespread activating approaches (such as glutaraldehyde, cyanogen bromide, divinylsulfone, carbodiimides, carbonyldiimidazole, sulfonyl chlorides, chlorocarbonates, N-hydroxysuccinimides.

  11. A Cost-Effective Physical Modeling Exercise to Develop Students' Understanding of Covalent Bonding

    Science.gov (United States)

    Turner, Kristy L.

    2016-01-01

    Chemical bonding is one of the basic concepts in chemistry, and the topic of covalent bonding forms an important core of knowledge for the high school chemistry student. For many teachers it is a challenging concept to teach, not least because it relies mainly on traditional instruction and written work. Similarly, many students find the topic…

  12. Covalently Cross-Linked Sulfone Polybenzimidazole Membranes with Poly(Vinylbenzyl Chloride) for Fuel Cell Applications

    DEFF Research Database (Denmark)

    Yang, Jingshuai; Aili, David; Li, Qingfeng

    2013-01-01

    Covalently cross-linked polymer membranes were fabricated from poly(aryl sulfone benzimidazole) (SO(2) PBI) and poly(vinylbenzyl chloride) (PVBCl) as electrolytes for high-temperature proton-exchange-membrane fuel cells. The cross-linking imparted organo insolubility and chemical stability against...

  13. Genus-two characters of the Ising model

    International Nuclear Information System (INIS)

    Choi, J.H.; Koh, I.G.

    1989-01-01

    As a first step in studying conformal theories on a higher-genus Riemann surface, we construct genus-two characters of the Ising model from their behavior in zero- and nonzero-homology pinching limits, the Goddard-Kent-Oliveco set-space construction, and the branching coefficients in the level-two A 1 /sup (1)/ Kac-Moody characters on the higher-genus Riemann surface

  14. Language Empowering in Character Building (Pemberdayaan Bahasa dalam Pembentukan Karakter

    Directory of Open Access Journals (Sweden)

    Kamsinah Kamsinah

    2013-10-01

    Full Text Available Character building is the most important thing to do as it is a striving system which underly behavior (Freud.  Even more, good character is more to be praised than outstanding talent. Most talents are to some extent a gift. Good character, however, is not given to us. we have to build it peace by peace by thought, choice, courage, and determination.  So important it is that it is said that  if there is no more character every thing is lost (Mahatma Gandhi. The best way to build it is  to develop   the function of all  individual potential,  including cognitive, affective,  and psychomotoric aspects simultanously in the context of socio-cultural interaction (in family, in  school, and in society. Character  is gained by nature and nurture. It can be done begin from the golden age to the old one through the three character building components: moral knowing, moral feeling, and moral action as suggested by Lickona. They make it possible since human beings, as  the best-formed creature of all, are the ones and the only creature posessing culture, and that,  they can educate and be educated in terms of   the model of  person of character.  Everybody must have character. Therefore,  to apply Lickona’s,  one must  empower her/his language, in which  she/he/ perform her/his competence in using language creativity (Chomsky in   both ordinary  and literary language. In this case, Buginese language is used as the sample.

  15. IMAGE TYPE WATER METER CHARACTER RECOGNITION BASED ON EMBEDDED DSP

    OpenAIRE

    LIU Ying; HAN Yan-bin; ZHANG Yu-lin

    2015-01-01

    In the paper, we combined DSP processor with image processing algorithm and studied the method of water meter character recognition. We collected water meter image through camera at a fixed angle, and the projection method is used to recognize those digital images. The experiment results show that the method can recognize the meter characters accurately and artificial meter reading is replaced by automatic digital recognition, which improves working efficiency.

  16. Javanese Character Feature Extraction Based on Shape Energy

    Directory of Open Access Journals (Sweden)

    Galih Hendra Wibowo

    2017-07-01

    Full Text Available Javanese character is one of Indonesia's noble culture, especially in Java. However, the number of Javanese people who are able to read the letter has decreased so that there need to be conservation efforts in the form of a system that is able to recognize the characters. One solution to these problem lies in Optical Character Recognition (OCR studies, where one of its heaviest points lies in feature extraction which is to distinguish each character. Shape Energy is one of feature extraction method with the basic idea of how the character can be distinguished simply through its skeleton. Based on the basic idea, then the development of feature extraction is done based on its components to produce an angular histogram with various variations of multiples angle. Furthermore, the performance test of this method and its basic method is performed in Javanese character dataset, which has been obtained from various images, is 240 data with 19 labels by using K-Nearest Neighbors as its classification method. Performance values were obtained based on the accuracy which is generated through the Cross-Validation process of 80.83% in the angular histogram with an angle of 20 degrees, 23% better than Shape Energy. In addition, other test results show that this method is able to recognize rotated character with the lowest performance value of 86% at 180-degree rotation and the highest performance value of 96.97% at 90-degree rotation. It can be concluded that this method is able to improve the performance of Shape Energy in the form of recognition of Javanese characters as well as robust to the rotation.

  17. Apology Strategies Performed By Main Characters In Perahu Kertas Novel

    OpenAIRE

    KUSUMA, DEVILIA INDAH

    2014-01-01

    Keywords: speech act, apology strategies, Perahu Kertas novel Apology is a part of human communication to maintain good relations between people or to restore harmony. The writer conducted a research on apology strategies in Bahasa Indonesia, by analyzing a novel entitled Perahu Kertas. In this study, there are two problems to be solved: (1) What apology strategies are performed by main characters in Perahu Kertas novel, and (2) How is the act of apologizing upgraded by main characters in Per...

  18. Systematic review of character development and childhood chronic illness.

    Science.gov (United States)

    Maslow, Gary R; Hill, Sherika N

    2016-05-08

    To review empirical evidence on character development among youth with chronic illnesses. A systematic literature review was conducted using PubMed and PSYCHINFO from inception until November 2013 to find quantitative studies that measured character strengths among youth with chronic illnesses. Inclusion criteria were limited to English language studies examining constructs of character development among adolescents or young adults aged 13-24 years with a childhood-onset chronic medical condition. A librarian at Duke University Medical Center Library assisted with the development of the mesh search term. Two researchers independently reviewed relevant titles (n = 549), then abstracts (n = 45), and finally manuscripts (n = 3). There is a lack of empirical research on character development and childhood-onset chronic medical conditions. Three studies were identified that used different measures of character based on moral themes. One study examined moral reasoning among deaf adolescents using Kohlberg's Moral Judgement Instrument; another, investigated moral values of adolescent cancer survivors with the Values In Action Classification of Strengths. A third study evaluated moral behavior among young adult survivors of burn injury utilizing the Tennessee Self-Concept, 2(nd) edition. The studies observed that youth with chronic conditions reasoned at less advanced stages and had a lower moral self-concept compared to referent populations, but that they did differ on character virtues and strengths when matched with healthy peers for age, sex, and race/ethnicity. Yet, generalizations could not be drawn regarding character development of youth with chronic medical conditions because the studies were too divergent from each other and biased from study design limitations. Future empirical studies should learn from the strengths and weaknesses of the existing literature on character development among youth with chronic medical conditions.

  19. Systematic review of character development and childhood chronic illness

    Science.gov (United States)

    Maslow, Gary R; Hill, Sherika N

    2016-01-01

    AIM: To review empirical evidence on character development among youth with chronic illnesses. METHODS: A systematic literature review was conducted using PubMed and PSYCHINFO from inception until November 2013 to find quantitative studies that measured character strengths among youth with chronic illnesses. Inclusion criteria were limited to English language studies examining constructs of character development among adolescents or young adults aged 13-24 years with a childhood-onset chronic medical condition. A librarian at Duke University Medical Center Library assisted with the development of the mesh search term. Two researchers independently reviewed relevant titles (n = 549), then abstracts (n = 45), and finally manuscripts (n = 3). RESULTS: There is a lack of empirical research on character development and childhood-onset chronic medical conditions. Three studies were identified that used different measures of character based on moral themes. One study examined moral reasoning among deaf adolescents using Kohlberg’s Moral Judgement Instrument; another, investigated moral values of adolescent cancer survivors with the Values In Action Classification of Strengths. A third study evaluated moral behavior among young adult survivors of burn injury utilizing the Tennessee Self-Concept, 2nd edition. The studies observed that youth with chronic conditions reasoned at less advanced stages and had a lower moral self-concept compared to referent populations, but that they did differ on character virtues and strengths when matched with healthy peers for age, sex, and race/ethnicity. Yet, generalizations could not be drawn regarding character development of youth with chronic medical conditions because the studies were too divergent from each other and biased from study design limitations. CONCLUSION: Future empirical studies should learn from the strengths and weaknesses of the existing literature on character development among youth with chronic medical conditions

  20. Reversible and formaldehyde-mediated covalent binding of a bis-amino mitoxantrone analogue to DNA.

    Science.gov (United States)

    Konda, Shyam K; Kelso, Celine; Pumuye, Paul P; Medan, Jelena; Sleebs, Brad E; Cutts, Suzanne M; Phillips, Don R; Collins, J Grant

    2016-05-18

    The ability of a bis-amino mitoxantrone anticancer drug (named WEHI-150) to form covalent adducts with DNA, after activation by formaldehyde, has been studied by electrospray ionisation mass spectrometry and HPLC. Mass spectrometry results showed that WEHI-150 could form covalent adducts with d(ACGCGCGT)2 that contained one, two or three covalent links to the octanucleotide, whereas the control drugs (daunorubicin and the anthracenediones mitoxantrone and pixantrone) only formed adducts with one covalent link to the octanucleotide. HPLC was used to examine the extent of covalent bond formation of WEHI-150 with d(CGCGCG)2 and d(CG(5Me)CGCG)2. Incubation of WEHI-150 with d(CG(5Me)CGCG)2 in the presence of formaldehyde resulted in the formation of significantly greater amounts of covalent adducts than was observed with d(CGCGCG)2. In order to understand the observed increase of covalent adducts with d(CG(5Me)CGCG)2, an NMR study of the reversible interaction of WEHI-150 at both CpG and (5Me)CpG sites was undertaken. Intermolecular NOEs were observed in the NOESY spectra of d(ACGGCCGT)2 with added WEHI-150 that indicated that the drug selectively intercalated at the CpG sites and from the major groove. In particular, NOEs were observed from the WEHI-150 H2,3 protons to the H1' protons of G3 and G7 and from the H6,7 protons to the H5 protons of C2 and C6. By contrast, intermolecular NOEs were observed between the WEHI-150 H2,3 protons to the H2'' proton of the (5Me)C3 in d(CG(5Me)CGCG)2, and between the drug aliphatic protons and the H1' proton of G4. This demonstrated that WEHI-150 preferentially intercalates at (5Me)CpG sites, compared to CpG sequences, and predominantly via the minor groove at the (5Me)CpG site. The results of this study demonstrate that WEHI-150 is likely to form interstrand DNA cross-links, upon activation by formaldehyde, and consequently exhibit greater cytotoxicity than other current anthracenedione drugs.

  1. Non-covalent interactions between {N,N′-bis[(2-pyridinyl)methylene]-1, 2-benzenediamine]-bis(nitrato)}Cu(II) with pyridoxine hydrochloride in methanol at T = (298.15, 308.15 and 318.15) K

    International Nuclear Information System (INIS)

    Brahman, Dhiraj; Sinha, Biswajit

    2014-01-01

    Highlights: • Methanolic solution of pyridoxine hydrochloride used as solvent. • {N,N′-bis[(2-pyridinyl)methylene]-1, 2-benzenediamine]-bis(nitrato)}Cu(II) used as solute. • Partial molar volumes and viscosity B-coefficients of the solute were determined. • Weak 1:1 association between the complex and pyridoxine hydrochloride found. • Non-covalent interactions and Cu(II) complex acts as a net structure maker in the ternary solutions. - Abstract: Non-covalent interactions between of {N,N′-bis[(2-pyridinyl)methylene]-1, 2-benzenediamine]-bis(nitrato)}Cu(II) with pyridoxine hydrochloride in methanol were investigated by a combination of physico-chemical and spectrophotometric methods at T = (298.15, 308.15 and 318.15) K under ambient pressure. From measured density and viscosity data the apparent molar volume (ϕ V ), the slope (S V ∗ ), standard partial molar volume (ϕ V 0 ), standard transfer volume (Δ t ϕ V 0 ), isobaric apparent molar expansibility (ϕ E ), standard isobaric partial molar expansibility (ϕ E 0 ), the viscosity B-coefficient, its temperature derivative (∂B/∂T), solvation number (S n ) were calculated and discussed on the basis of specific or non-specific (solute + cosolute) and (solute + solvent) interactions. Thermodynamics of viscous flow were discussed on the basis of the transition state theory. Spectrophotometric results indicated 1:1 (solute + cosolute) interaction between the complex and pyridoxine hydrochloride

  2. Glyph Identification and Character Recognition for Sindhi OCR

    Directory of Open Access Journals (Sweden)

    NISAR AHMEDMEMON

    2017-10-01

    Full Text Available A computer can read and write multiple languages and today?s computers are capable of understanding various human languages. A computer can be given instructions through various input methods but OCR (Optical Character Recognition and handwritten character recognition are the input methods in which a scanned page containing text is converted into written or editable text. The change in language text available on scanned page demands different algorithm to recognize text because every language and script pose varying number of challenges to recognize text. The Latin language recognition pose less difficulties compared to Arabic script and languages that use Arabic script for writing and OCR systems for these Latin languages are near to perfection. Very little work has been done on regional languages of Pakistan. In this paper the Sindhi glyphs are identified and the number of characters and connected components are identified for this regional language of Pakistan. A graphical user interface has been created to perform identification task for glyphs and characters of Sindhi language. The glyphs of characters are successfully identified from scanned page and this information can be used to recognize characters. The language glyph identification can be used to apply suitable algorithm to identify language as well as to achieve a higher recognition rate.

  3. Effect of refractive error on temperament and character properties

    Institute of Scientific and Technical Information of China (English)

    Emine; Kalkan; Akcay; Fatih; Canan; Huseyin; Simavli; Derya; Dal; Hacer; Yalniz; Nagihan; Ugurlu; Omer; Gecici; Nurullah; Cagil

    2015-01-01

    AIM: To determine the effect of refractive error on temperament and character properties using Cloninger’s psychobiological model of personality.METHODS: Using the Temperament and Character Inventory(TCI), the temperament and character profiles of 41 participants with refractive errors(17 with myopia,12 with hyperopia, and 12 with myopic astigmatism) were compared to those of 30 healthy control participants.Here, temperament comprised the traits of novelty seeking, harm-avoidance, and reward dependence, while character comprised traits of self-directedness,cooperativeness, and self-transcendence.RESULTS: Participants with refractive error showed significantly lower scores on purposefulness,cooperativeness, empathy, helpfulness, and compassion(P <0.05, P <0.01, P <0.05, P <0.05, and P <0.01,respectively).CONCLUSION: Refractive error might have a negative influence on some character traits, and different types of refractive error might have different temperament and character properties. These personality traits may be implicated in the onset and/or perpetuation of refractive errors and may be a productive focus for psychotherapy.

  4. Brain Activity while Reading Sentences with Kanji Characters Expressing Emotions

    Science.gov (United States)

    Yuasa, Masahide; Saito, Keiichi; Mukawa, Naoki

    In this paper, we describe the brain activity associated with kanji characters expressing emotion, which are places at the end of a sentence. Japanese people use a special kanji character in brackets at the end of sentences in text messages such as those sent through e-mail and messenger tools. Such kanji characters plays a role to expresses the sender's emotion (such as fun, laughter, sadness, tears), like emoticons. It is a very simple and effective way to convey the senders' emotions and his/her thoughts to the receiver. In this research, we investigate the effects of emotional kanji characters by using an fMRI study. The experimental results show that both the right and left inferior frontal gyrus, which have been implicated on verbal and nonverbal information, were activated. We found that we detect a sentence with an emotional kanji character as the verbal and nonverval information, and a sentence with emotional kanji characters enrich communication between the sender and the reciever.

  5. Temperament, Character, and Adolescents' Depressive Symptoms: Focusing on Affect

    Directory of Open Access Journals (Sweden)

    Danilo Garcia

    2012-01-01

    Full Text Available Positive (PA and negative affect (NA are two separate systems markers of subjective well-being and measures of the state depression (low PA combined with high NA. The present study investigated differences in temperament, character, locus of control, and depressive symptoms (sleep quality, stress, and lack of energy between affective profiles in an adolescent sample. Participants (=304 were categorized into four affective profiles: “self-fulfilling” (high PA, low NA, “high affective” (high PA, high NA, “low affective” (low PA, low NA, and “self-destructive” (low PA, high NA. Personality was measured by the Temperament and Character Inventory and affective profiles by the Positive Affect and Negative Affect Schedule. The “self-fulfilling” profile was characterized by, compared to the other affective profiles, higher levels of sleep quality, less stress and more energy and also higher levels of persistence and a mature character (i.e., high scores in self-directedness and cooperativeness. “Self-destructive” adolescents reported higher levels of external locus of control, high scores in harm avoidance and reward dependence combined with less mature character. The results identify the importance of character maturity in well-being and suggest that depressive state can be positively influenced by promoting positive emotions which appears to be achieved by character development.

  6. Efficient learning strategy of Chinese characters based on network approach.

    Directory of Open Access Journals (Sweden)

    Xiaoyong Yan

    Full Text Available We develop an efficient learning strategy of Chinese characters based on the network of the hierarchical structural relations between Chinese characters. A more efficient strategy is that of learning the same number of useful Chinese characters in less effort or time. We construct a node-weighted network of Chinese characters, where character usage frequencies are used as node weights. Using this hierarchical node-weighted network, we propose a new learning method, the distributed node weight (DNW strategy, which is based on a new measure of nodes' importance that considers both the weight of the nodes and its location in the network hierarchical structure. Chinese character learning strategies, particularly their learning order, are analyzed as dynamical processes over the network. We compare the efficiency of three theoretical learning methods and two commonly used methods from mainstream Chinese textbooks, one for Chinese elementary school students and the other for students learning Chinese as a second language. We find that the DNW method significantly outperforms the others, implying that the efficiency of current learning methods of major textbooks can be greatly improved.

  7. Research of Simulation in Character Animation Based on Physics Engine

    Directory of Open Access Journals (Sweden)

    Yang Yu

    2017-01-01

    Full Text Available Computer 3D character animation essentially is a product, which is combined with computer graphics and robotics, physics, mathematics, and the arts. It is based on computer hardware and graphics algorithms and related sciences rapidly developed new technologies. At present, the mainstream character animation technology is based on the artificial production of key technologies and capture frames based on the motion capture device technology. 3D character animation is widely used not only in the production of film, animation, and other commercial areas but also in virtual reality, computer-aided education, flight simulation, engineering simulation, military simulation, and other fields. In this paper, we try to study physics based character animation to solve these problems such as poor real-time interaction that appears in the character, low utilization rate, and complex production. The paper deeply studied the kinematics, dynamics technology, and production technology based on the motion data. At the same time, it analyzed ODE, PhysX, Bullet, and other variety of mainstream physics engines and studied OBB hierarchy bounding box tree, AABB hierarchical tree, and other collision detection algorithms. Finally, character animation based on ODE is implemented, which is simulation of the motion and collision process of a tricycle.

  8. Experts' understanding of partial derivatives using the Partial Derivative Machine

    OpenAIRE

    Roundy, David; Dorko, Allison; Dray, Tevian; Manogue, Corinne A.; Weber, Eric

    2014-01-01

    Partial derivatives are used in a variety of different ways within physics. Most notably, thermodynamics uses partial derivatives in ways that students often find confusing. As part of a collaboration with mathematics faculty, we are at the beginning of a study of the teaching of partial derivatives, a goal of better aligning the teaching of multivariable calculus with the needs of students in STEM disciplines. As a part of this project, we have performed a pilot study of expert understanding...

  9. Production of recombinant cholesterol oxidase containing covalently bound FAD in Escherichia coli

    Directory of Open Access Journals (Sweden)

    Molla Gianluca

    2010-04-01

    Full Text Available Abstract Background Cholesterol oxidase is an alcohol dehydrogenase/oxidase flavoprotein that catalyzes the dehydrogenation of C(3-OH of cholesterol. It has two major biotechnological applications, i.e. in the determination of serum (and food cholesterol levels and as biocatalyst providing valuable intermediates for industrial steroid drug production. Cholesterol oxidases of type I are those containing the FAD cofactor tightly but not covalently bound to the protein moiety, whereas type II members contain covalently bound FAD. This is the first report on the over-expression in Escherichia coli of type II cholesterol oxidase from Brevibacterium sterolicum (BCO. Results Design of the plasmid construct encoding the mature BCO, optimization of medium composition and identification of the best cultivation/induction conditions for growing and expressing the active protein in recombinant E. coli cells, concurred to achieve a valuable improvement: BCO volumetric productivity was increased from ~500 up to ~25000 U/L and its crude extract specific activity from 0.5 up to 7.0 U/mg protein. Interestingly, under optimal expression conditions, nearly 55% of the soluble recombinant BCO is produced as covalently FAD bound form, whereas the protein containing non-covalently bound FAD is preferentially accumulated in insoluble inclusion bodies. Conclusions Comparison of our results with those published on non-covalent (type I COs expressed in recombinant form (either in E. coli or Streptomyces spp., shows that the fully active type II BCO can be produced in E. coli at valuable expression levels. The improved over-production of the FAD-bound cholesterol oxidase will support its development as a novel biotool to be exploited in biotechnological applications.

  10. Partial Actions and Power Sets

    Directory of Open Access Journals (Sweden)

    Jesús Ávila

    2013-01-01

    Full Text Available We consider a partial action (X,α with enveloping action (T,β. In this work we extend α to a partial action on the ring (P(X,Δ,∩ and find its enveloping action (E,β. Finally, we introduce the concept of partial action of finite type to investigate the relationship between (E,β and (P(T,β.

  11. Algorithms over partially ordered sets

    DEFF Research Database (Denmark)

    Baer, Robert M.; Østerby, Ole

    1969-01-01

    in partially ordered sets, answer the combinatorial question of how many maximal chains might exist in a partially ordered set withn elements, and we give an algorithm for enumerating all maximal chains. We give (in § 3) algorithms which decide whether a partially ordered set is a (lower or upper) semi......-lattice, and whether a lattice has distributive, modular, and Boolean properties. Finally (in § 4) we give Algol realizations of the various algorithms....

  12. Anatomic partial nephrectomy: technique evolution.

    Science.gov (United States)

    Azhar, Raed A; Metcalfe, Charles; Gill, Inderbir S

    2015-03-01

    Partial nephrectomy provides equivalent long-term oncologic and superior functional outcomes as radical nephrectomy for T1a renal masses. Herein, we review the various vascular clamping techniques employed during minimally invasive partial nephrectomy, describe the evolution of our partial nephrectomy technique and provide an update on contemporary thinking about the impact of ischemia on renal function. Recently, partial nephrectomy surgical technique has shifted away from main artery clamping and towards minimizing/eliminating global renal ischemia during partial nephrectomy. Supported by high-fidelity three-dimensional imaging, novel anatomic-based partial nephrectomy techniques have recently been developed, wherein partial nephrectomy can now be performed with segmental, minimal or zero global ischemia to the renal remnant. Sequential innovations have included early unclamping, segmental clamping, super-selective clamping and now culminating in anatomic zero-ischemia surgery. By eliminating 'under-the-gun' time pressure of ischemia for the surgeon, these techniques allow an unhurried, tightly contoured tumour excision with point-specific sutured haemostasis. Recent data indicate that zero-ischemia partial nephrectomy may provide better functional outcomes by minimizing/eliminating global ischemia and preserving greater vascularized kidney volume. Contemporary partial nephrectomy includes a spectrum of surgical techniques ranging from conventional-clamped to novel zero-ischemia approaches. Technique selection should be tailored to each individual case on the basis of tumour characteristics, surgical feasibility, surgeon experience, patient demographics and baseline renal function.

  13. Partial order infinitary term rewriting

    DEFF Research Database (Denmark)

    Bahr, Patrick

    2014-01-01

    We study an alternative model of infinitary term rewriting. Instead of a metric on terms, a partial order on partial terms is employed to formalise convergence of reductions. We consider both a weak and a strong notion of convergence and show that the metric model of convergence coincides with th...... to the metric setting -- orthogonal systems are both infinitarily confluent and infinitarily normalising in the partial order setting. The unique infinitary normal forms that the partial order model admits are Böhm trees....

  14. The dark cube: dark and light character profiles

    Directory of Open Access Journals (Sweden)

    Danilo Garcia

    2016-02-01

    Full Text Available Background. Research addressing distinctions and similarities between people’s malevolent character traits (i.e., the Dark Triad: Machiavellianism, narcissism, and psychopathy has detected inconsistent linear associations to temperament traits. Additionally, these dark traits seem to have a common core expressed as uncooperativeness. Hence, some researchers suggest that the dark traits are best represented as one global construct (i.e., the unification argument rather than as ternary construct (i.e., the uniqueness argument. We put forward the dark cube (cf. Cloninger’s character cube comprising eight dark profiles that can be used to compare individuals who differ in one dark character trait while holding the other two constant. Our aim was to investigate in which circumstances individuals who are high in each one of the dark character traits differ in Cloninger’s “light” character traits: self-directedness, cooperativeness, and self-transcendence. We also investigated if people’s dark character profiles were associated to their light character profiles. Method. A total of 997 participants recruited from Amazon’s Mechanical Turk (MTurk responded to the Short Dark Triad and the Short Character Inventory. Participants were allocated to eight different dark profiles and eight light profiles based on their scores in each of the traits and any possible combination of high and low scores. We used three-way interaction regression analyses and t-tests to investigate differences in light character traits between individuals with different dark profiles. As a second step, we compared the individuals’ dark profile with her/his character profile using an exact cell-wise analysis conducted in the ROPstat software (http://www.ropstat.com. Results. Individuals who expressed high levels of Machiavellianism and those who expressed high levels of psychopathy also expressed low self-directedness and low cooperativeness. Individuals with high

  15. Optical character recognition of handwritten Arabic using hidden Markov models

    Science.gov (United States)

    Aulama, Mohannad M.; Natsheh, Asem M.; Abandah, Gheith A.; Olama, Mohammed M.

    2011-04-01

    The problem of optical character recognition (OCR) of handwritten Arabic has not received a satisfactory solution yet. In this paper, an Arabic OCR algorithm is developed based on Hidden Markov Models (HMMs) combined with the Viterbi algorithm, which results in an improved and more robust recognition of characters at the sub-word level. Integrating the HMMs represents another step of the overall OCR trends being currently researched in the literature. The proposed approach exploits the structure of characters in the Arabic language in addition to their extracted features to achieve improved recognition rates. Useful statistical information of the Arabic language is initially extracted and then used to estimate the probabilistic parameters of the mathematical HMM. A new custom implementation of the HMM is developed in this study, where the transition matrix is built based on the collected large corpus, and the emission matrix is built based on the results obtained via the extracted character features. The recognition process is triggered using the Viterbi algorithm which employs the most probable sequence of sub-words. The model was implemented to recognize the sub-word unit of Arabic text raising the recognition rate from being linked to the worst recognition rate for any character to the overall structure of the Arabic language. Numerical results show that there is a potentially large recognition improvement by using the proposed algorithms.

  16. Distributional Similarity for Chinese: Exploiting Characters and Radicals

    Directory of Open Access Journals (Sweden)

    Peng Jin

    2012-01-01

    Full Text Available Distributional Similarity has attracted considerable attention in the field of natural language processing as an automatic means of countering the ubiquitous problem of sparse data. As a logographic language, Chinese words consist of characters and each of them is composed of one or more radicals. The meanings of characters are usually highly related to the words which contain them. Likewise, radicals often make a predictable contribution to the meaning of a character: characters that have the same components tend to have similar or related meanings. In this paper, we utilize these properties of the Chinese language to improve Chinese word similarity computation. Given a content word, we first extract similar words based on a large corpus and a similarity score for ranking. This rank is then adjusted according to the characters and components shared between the similar word and the target word. Experiments on two gold standard datasets show that the adjusted rank is superior and closer to human judgments than the original rank. In addition to quantitative evaluation, we examine the reasons behind errors drawing on linguistic phenomena for our explanations.

  17. Personality, temperament and character in Erich Fromm's theory

    Directory of Open Access Journals (Sweden)

    Redžić Saduša F.

    2012-01-01

    Full Text Available The character of the man is the substitute for instincts that animals have. In reality characters are not found in pure form, as specified orientation, but as a mixture of types. The social character of Fromm has an ethical and heuristic importance. Human passions are rooted in character and are a way to give meaning to existence, to respond to the human existential situation. If we are not able to respond through the love, then, in the absence of, we turn to destructiveness. According to Fromm, the most important goal of society should be human development. He lays down a rational belief in critical thought coupled with love of life. Although the development of personality is largely determined by social structure, Fromm concludes it is not entirely passive, that a man has the opportunity, space and power to use his mind to react to the alienation and inhumane living conditions. Through analysis of the social character From is giving a kind of critique of modern, market-oriented society, based on the principles of humanistic ethics. .

  18. On defining a unique phylogenetic tree with homoplastic characters.

    Science.gov (United States)

    Goloboff, Pablo A; Wilkinson, Mark

    2018-05-01

    This paper discusses the problem of whether creating a matrix with all the character state combinations that have a fixed number of steps (or extra steps) on a given tree T, produces the same tree T when analyzed with maximum parsimony or maximum likelihood. Exhaustive enumeration of cases up to 20 taxa for binary characters, and up to 12 taxa for 4-state characters, shows that the same tree is recovered (as unique most likely or most parsimonious tree) as long as the number of extra steps is within 1/4 of the number of taxa. This dependence, 1/4 of the number of taxa, is discussed with a general argumentation, in terms of the spread of the character changes on the tree used to select character state distributions. The present finding allows creating matrices which have as much homoplasy as possible for the most parsimonious or likely tree to be predictable, and examination of these matrices with hill-climbing search algorithms provides additional evidence on the (lack of a) necessary relationship between homoplasy and the ability of search methods to find optimal trees. Copyright © 2018 Elsevier Inc. All rights reserved.

  19. Character convergence under competition for nutritionally essential resources.

    Science.gov (United States)

    Fox, Jeremy W; Vasseur, David A

    2008-11-01

    Resource competition is thought to drive divergence in resource use traits (character displacement) by generating selection favoring individuals able to use resources unavailable to others. However, this picture assumes nutritionally substitutable resources (e.g., different prey species). When species compete for nutritionally essential resources (e.g., different nutrients), theory predicts that selection drives character convergence. We used models of two species competing for two essential resources to address several issues not considered by existing theory. The models incorporated either slow evolutionary change in resource use traits or fast physiological or behavioral change. We report four major results. First, competition always generates character convergence, but differences in resource requirements prevent competitors from evolving identical resource use traits. Second, character convergence promotes coexistence. Competing species always attain resource use traits that allow coexistence, and adaptive trait change stabilizes the ecological equilibrium. In contrast, adaptation in allopatry never preadapts species to coexist in sympatry. Third, feedbacks between ecological dynamics and trait dynamics lead to surprising dynamical trajectories such as transient divergence in resource use traits followed by subsequent convergence. Fourth, under sufficiently slow trait change, ecological dynamics often drive one of the competitors to near extinction, which would prevent realization of long-term character convergence in practice.

  20. Character evolution and missing (morphological) data across Asteridae.

    Science.gov (United States)

    Stull, Gregory W; Schori, Melanie; Soltis, Douglas E; Soltis, Pamela S

    2018-04-14

    Our current understanding of flowering plant phylogeny provides an excellent framework for exploring various aspects of character evolution through comparative analyses. However, attempts to synthesize this phylogenetic framework with extensive morphological data sets have been surprisingly rare. Here, we explore character evolution in Asteridae (asterids), a major angiosperm clade, using an extensive morphological data set and a well-resolved phylogeny. We scored 15 phenotypic characters (spanning chemistry, vegetative anatomy, and floral, fruit, and seed features) across 248 species for ancestral state reconstruction using a phylogenetic framework based on 73 plastid genes and the same 248 species. Iridoid production, unitegmic ovules, and cellular endosperm were all reconstructed as synapomorphic for Asteridae. Sympetaly, long associated with asterids, shows complex patterns of evolution, suggesting it arose several times independently within the clade. Stamens equal in number to the petals is likely a synapomorphy for Gentianidae, a major asterid subclade. Members of Lamianae, a major gentianid subclade, are potentially diagnosed by adnate stamens, unilacunar nodes, and simple perforation plates. The analyses presented here provide a greatly improved understanding of character evolution across Asteridae, highlighting multiple characters potentially synapomorphic for major clades. However, several important parts of the asterid tree are poorly known for several key phenotypic features (e.g., degree of petal fusion, integument number, nucellus type, endosperm type, iridoid production). Further morphological, anatomical, developmental, and chemical investigations of these poorly known asterids are critical for a more detailed understanding of early asterid evolution. © 2018 Botanical Society of America.