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Sample records for paris-chitanvis muriel siebert

  1. Voodoo rahva valitseja / Aino Siebert

    Index Scriptorium Estoniae

    Siebert, Aino

    2008-01-01

    Saksa-Eesti Foorumi esimees, vabakutseline ajakirjanik Aino Siebert kohtus voodoo kodumaana tuntud Benini kuningaga. Monarh on salapärases nõiakunstis meister nagu ka paljud tema kümnetest miljonitest alamatest

  2. The secular and the supernatural: madness and psychiatry in the short stories of Muriel Spark.

    Science.gov (United States)

    Beveridge, A W

    2015-01-01

    Edinburgh-born Muriel Spark is one of modern Scotland's greatest writers. Examination of her work reveals that the subjects of madness and psychiatry are recurrent themes in her writing. She herself had a mental breakdown when she was a young woman and she took an interest in the world of psychiatry and psychoanalysis. In her short stories, Spark approaches the subject of madness in a variety of ways: she relates it to the supernatural; to writing fiction; and to religion. She frequently juxtaposes secular and supernatural explanations of mental disturbance. Spark adopts a sceptical and, at times, mocking view of psychiatrists and psychiatric treatment. Both psychoanalysis and pills are seen as problematic.

  3. Sweet old things: moral complexities in old age in Muriel Spark's Memento Mori.

    Science.gov (United States)

    England, Suzanne E; Rust, Martha D

    2015-04-01

    Through the lens of Muriel Spark's dark comedic novel, Memento Mori, this paper explores questions of morality, mortality, and the moral choices and performances in old age and in the systems and places of care. Spark's elderly characters are complex moral actors - some virtuous and some decidedly not - who have been receiving mysterious phone calls telling them simply, "Remember you must die." We, the co-authors, are from two different disciplines, namely Renaissance and medieval literature, and social work and critical gerontology. Among the questions that interest us is the paradox of a master narrative that on the one hand exempts the old from moral criticism yet holds them to a higher moral standard - essentially positioning them as moral nonentities, and relieving the old, their caretakers, and society of moral responsibility. Another is the question of whether moral agency in old age has distinctive aspects, and whether consciousness of one's impending mortality effects moral reasoning and performance. In this paper we offer our individual readings of the ways the novel opens up conceptual space in aging theory, and conclude with our thoughts about what our collaboration suggests for continuing cross-disciplinary dialogue. Copyright © 2015 Elsevier Inc. All rights reserved.

  4. Beatrice Muriel Hill Tinsley

    Indian Academy of Sciences (India)

    Virginia Trimble

    Much of the rest of her tragically short career was spent in improving ... reference to one or two other astronomers (also, as it happens, women, ... came one of the first research students in the new astronomy ... an essential part of trying to use galaxies to do cosmology, and .... very fundamental things about stars. The first.

  5. Welcome to Muriel!

    CERN Multimedia

    Gagnon, P.

    2006-01-01

    As the new editor of the ATLAS e-news, I would like to take this opportunity to open a new forum for people's opinions and comments. Over the past few years, through the ATLAS e-news, we had a chance to read about progress, achievements and milestones reached by our colleagues. It has provided the well desserved visibility to each group willing to show their work to the rest of the collaboration, share nice pictures on various social events, hear the latest from the management and keep abreast with the progress of the experiment as a whole. At this point, I think it is time to open a new column in this page where everybody could express their opinion, share information or start a debate on a subject they deem of interest to the collaboration. Of course, given that the ATLAS collaboration has several thousands people from more than 150 different institutes, such an enterprise is risky. Therefore, after consulting with the CERN legal office, I have hired an expert to moderate this column and avoid any sort of ...

  6. Masculine and Feminine Insights Into the Fantastic World of Elves: J.R.R. Tolkien’s the Lord of the Rings and Muriel Barbery’s the Life of Elves

    Directory of Open Access Journals (Sweden)

    Măcineanu Laura

    2016-12-01

    Full Text Available The paper focuses on the fantasy universes created by J.R.R. Tolkien and by the more recent French writer, Muriel Barbery. The two authors excel in their depiction of the elusive world of the elves, each offering a deeply personal vision (a man writer’s and a woman writer’s of what such magical beings may be like and how they may relate to humankind.

  7. Tugi Eesti lastekodulastele / Aino Siebert

    Index Scriptorium Estoniae

    Siebert, Aino

    2004-01-01

    7. mail Karlsruhe lähistel Eggensteini evangeelses kirikus toimunud rahvusvahelisest heategevuskontserdist, millega toetatakse eesti lastekodudes elavaid lapsi (kontserdi korraldajaks Heidelbergis asutatud Saksa-Eesti Foorum (SEF))

  8. Valimised tõid segaduse / Aino Siebert

    Index Scriptorium Estoniae

    Siebert, Aino

    2005-01-01

    Saksa Bundestagi 16. valimistel ei saanud uue valitsuse loomiseks enamust ei CDU/CSU-blokk (Kristlik-Demokraatlik Liit ja Kristlik-Sotsiaalne Liit) ega SPD (Sotsiaaldemokraatlik Partei). Vt. ka: Kantslerikandidaat tuleb idast. Saksamaa kantslerikandidaat Angela Merkel

  9. Il razzismo: il riconoscimento negato (Renate Siebert

    Directory of Open Access Journals (Sweden)

    Francesco Bachis

    2004-12-01

    Full Text Available Consacreremo la prima parte di quest'articolo alle manifestazioni corporee dell'emozione. La psicologia sperimentale, insieme alla neuro-biologia, hanno evidenziato le differenti risposte corporee più o meno percettibili. Ma al di là di queste manifestazioni puramente oggettive le cui percentuali e oscillazioni possono essere valutate, misurate ... E' l'aspetto soggettivo e le loro ripercussioni che c'interessa. Quali significati possono avere le emozioni per la persona che le prova? Questi temi saranno l'oggetto della seconda parte. Ci situiamo in quanto ricercatori che interrogano altri soggetti, ma è evidente che non possiamo fare astrazione delle nostre passioni.

  10. Saksamaal kõlas nii klassika kui "juhtmemuusika" / Aino Siebert ; fotod: Werner Siebert

    Index Scriptorium Estoniae

    Siebert, Aino

    2008-01-01

    Mainzi Maakonnamuuseumis avatud Gottlieb Welté näituse "Lihvimata geniaalsus" raames toimunud Eesti päevast 30. märtsil. Karlsruhe ZKMis (Kunsti- ja Meediatehnoloogia keskus) avatud festivalist Performance-Art - kaasaegne tants ja uued meediad. Festival leiab aset Baden-Württembergi liidumaal toimuvate kultuuriürituste raames

  11. Platelet-rich plasma in clinical practice | Siebert | South African ...

    African Journals Online (AJOL)

    PRP has also been used in orthopaedics for bone, tendon and muscle injuries, dentistry for dental implants, dermatology for wound healing, and in pathological conditions such as alopecia aereata. However, more recently, it has been used in the fast-growing field of aesthetic and anti-ageing medicine for skin rejuvenation.

  12. Saksa-Eesti Foorum tähistas vabariigi 88. aastapäeva / Aino Siebert ; fotod: Aino Siebert

    Index Scriptorium Estoniae

    Siebert, Aino

    2006-01-01

    Heidelbergi Providenz kiriku saalis, avasõnad ütles allakirjutanu, natolaste tervitused ütles Ilmar Tamm, üliõpilaste nimel esines Liisi Karindi, peokõne pidas Kaspar Näf, kontsertosas esinesid Triin Maran ja Triinu Kull-Boutahir

  13. Eesti rootslased Göteborgi raamatumessil "Bok & Bibliotek" / Aino Siebert, Georg von Stackelberg

    Index Scriptorium Estoniae

    Siebert, Aino

    2007-01-01

    rets. rmt.: "Runö" historien om svenskön i Rigabukten" / koostaja Jörgen Hedman. "Estlandsvenskarna som kom till Roslagen" / koostaja Kristina Rosen. "Berättelser från Nargö" - "Naisaare Lood" / koostaja Margit Rosen Norlin. "Kärslätt min by" / koostaja Sven Svärd

  14. Berliini ülemlinnapea usub, et homo võib saada kantsleriks / Aino Siebert

    Index Scriptorium Estoniae

    Siebert, Aino

    2009-01-01

    Samal ajal, kui Eesti meedias peavad kommentaatorid homoseksuaalse orientatsiooniga inimestele jahti, võtavad sakslased asja iseenesestmõistetavusega. Homoseksuaalsest Berliini ülemlinnapeast Klaus Wowereitist

  15. Prosthetic rehabilitation of severe Siebert's Class III defect with modified Andrews bridge system

    OpenAIRE

    Rathee, Manu; Sikka, Neha; Jindal, Sahil; Kaushik, Ashutosh

    2015-01-01

    Prosthetic dentistry involves the replacement of missing and contiguous tissues with artificial substitutes to restore and maintain the oral functions, appearance, and health of the patient. The treatment of edentulous areas with ridge defects poses a challenging task for the dentist. Management of such cases involves a wide range of treatment options comprising mainly of surgical interventions and non surgical techniques such as use of removable, fixed or fixed- removable partial dentures. B...

  16. Pärnu ettevõtjad IMEX-messil Frankfurdis / Aino Siebert

    Index Scriptorium Estoniae

    Siebert, Aino

    2007-01-01

    IMEX - "Incorporating Meeting for incentive travel, meetings and events" on rahvusvaheline globaalne näitus ettevõtjatele, kes organiseerivad messe, konverentse ja kokkutulekuid. Selle aasta messile Saksamaale saabus 150 riigist 3400 firmat

  17. Topical Meeting on Optical Bistability Held at Rochester, New York on 15-17 June 1983.

    Science.gov (United States)

    1983-01-01

    ThB16-1 SELF-BEATING INSTABILITIES IN BISTABLE DEVICES J.A. MARTIN-PEREDA .. M.A. MURIEL DEPARTAMENTO DE ELECTRONICA CUANTICA E.T.S. ING...OPTICAL BISTABLL SYSTEMS J.A. MARTIN PEREDA M.A. MURIEL ; DEPARTAMENIO DE ELECTRONICA CUANTICA E.T.S. ING. TELLCOMUNICACION UNIVERSIDAD POLITECNICA DE

  18. Untimely Resnais: Muriel’s Disarticulations of Justice

    OpenAIRE

    McMahon, Laura

    2016-01-01

    This is the final version of the article. It first appeared from Edinburgh University Press via https://doi.org 10.3366/film.2016.0012 Alain Resnais's 1963 film Muriel ou le temps d'un retour (Muriel, or the Time of Return) has been read in terms of a failure to engage with the historical and political issues surrounding the Algerian War – a failure viewed by Susan Sontag as a consequence of Resnais's favouring of aesthetics over politics. This essay reconsiders Muriel beyond the terms...

  19. Prevalence of Mantoux test positivity among apparently healthy ...

    African Journals Online (AJOL)

    The impact of tuberculosis (TB) is highest in the developing countries of Asia and Africa, especially among ... All children who fulfilled the inclusion criteria were evaluated for a history of ... Purified protein derivative-Siebert (PPD-S) stabilised.

  20. The Role of Trustworthiness in Teaching: An Examination of "The Prime of Miss Jean Brodie"

    Science.gov (United States)

    Katz, Michael S.

    2014-01-01

    The purpose of this paper is to examine the role that trustworthiness plays in the ability of teachers to function as moral role models. Through exploration of Muriel Spark's novel, "The Prime of Miss Jean Brodie," I explain some of the central features of trustworthiness as a moral virtue and suggest how these features are critical…

  1. 2008. aasta menukaimad / Udo Uibo

    Index Scriptorium Estoniae

    Uibo, Udo, 1956-

    2009-01-01

    2008. aasta raamatumüügi tulemustest, mulluste menukamate kirjanike nimestikust, mis põhineb USA, Suurbritannia, Prantsusmaa, Saksamaa, Itaalia, Hollandi, Hiina, Hispaania ja Rootsi igakuistel ilukirjanduslike bestsellerite edetabelitel. Esikümnesse kuuluvad: Khaled Hossein, Stieg Larsson, Ken Follett, Stephenie Meyer, Muriel Barbery, Carlos Ruiz Zafón, Anna Gavalda, John Grisham, J. K. Rowling, Henning Mankell

  2. African Journal of Neurological Sciences - Vol 34, No 2 (2015)

    African Journals Online (AJOL)

    Approche socio-culturelle de l'epilepsie en Cote d'Ivoire · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Felix Boa Yapo, Mariam Doumbia-Ouattara, Leonard Kouassi Kouame, Ismaila Diakite, Muriel Amon-Tanoh, Therese Sonan-Douayoua, 6-12 ...

  3. An Analysis of the Causes and Consequences of Kidnapping in ...

    African Journals Online (AJOL)

    Nneka Umera-Okeke

    Using secondary qualitative data, the study found out that kidnapping has been ... victims and their relatives, as well as the State at large. This requires a ... to child abduction, though she viewed it from the global perspective. File-Muriel ... Kidnapping is defined by various scholars with varying degree of successes. Firstly,.

  4. Kantsler Angela Merkel lubas Saksa majanduse käima tõmmata / Kaivo Kopli

    Index Scriptorium Estoniae

    Kopli, Kaivo

    2005-01-01

    Saksa kantsler Angela Merkel pidas parlamendis esimese programmilise kõne. Kriitikute hinnangul jäi Merkel üldsõnaliseks. Lisa: Saksamaa ei lase end shantazheerida. Vt. samas: Aino Siebert. Saksamaa liidukantsler saab palka töölepinguta

  5. Keys to the Stars : A Unique Experience

    NARCIS (Netherlands)

    Barthel, P.

    The International Year of Astronomy 2009 saw the birth of a remarkable arts and science collaboration, between a piano duo and an astronomer. Since 2009, the Dutch Grieg Piano Duo, consisting of the professional pianists Elles van der Heiden and Siebert Nix, and the author have performed together in

  6. Keys to the Stars — A Unique Experience

    NARCIS (Netherlands)

    Barthel, P.

    The International Year of Astronomy 2009 saw the birth of a remarkable arts and science collaboration, between a piano duo and an astronomer. Since 2009, the Dutch Grieg Piano Duo, consisting of the professional pianists Elles van der Heiden and Siebert Nix, and the author have performed together in

  7. Browse Title Index

    African Journals Online (AJOL)

    Items 101 - 150 of 243 ... Vol 15, No 2 (2005), Management strategies for recurrent epithelial ovarian cancer : review article, Abstract. HL Chauke. Vol 17, No 3 (2007), Maternal and ... Vol 21, No 1 (2011), Ovulation induction in women with polycystic ovarian syndrome, Abstract. TI Siebert, TF Kruger. Vol 20, No 1 (2010) ...

  8. Haavatutelaeva Steuben hukkumine Läänemerel / Vaino Kallas

    Index Scriptorium Estoniae

    Kallas, Vaino, 1927-

    2008-01-01

    Sakslaste reisilaevast Wilhelm Gustloffist, millel oli suur roll Teises maailmasõjas. Samal teemal : Aino Siebert "Sakslaste trauma - Wilhelm Gustloffi hukkumine" (Pärnu Postimees 17.07.08) ja Küllo Arjakas "Täienduseks Saksa reisilaeva Wilhelm Gustloffi hukkumise loole" (Pärnu Postimees 29.08.08)

  9. Some special moments from last month

    CERN Multimedia

    Claudia Marcelloni de Oliveira

    Integration of the three shells into the ATLAS pixel barrel last month. Lowering of the first sector of the MDT Muon Big Wheel on side C in the ATLAS cavern in December 2006. Some intense moment during the first ATLAS integration run from the main ATLAS control room. Muriel was one of the 20000 ATLAS cavern visitors in 2006 to enjoy herself during her visit.

  10. Photos of the month

    CERN Multimedia

    Claudia Marcelloni de Oliveira

    View of the End Cap Calorimeter side A in the ATLAS cavern during the opening of the detector. View of the End Cap Calorimeter side A from within the center of the ATLAS detector. The Muon Drift Tube Big Wheel on side C is being mechanically assembled. Krzysztof Ciba and his Apple computer. The ATLAS e-news co-editor, Muriel, received a special medal last week for distinguished journalism for her Mu-Mews.

  11. The Need for a Regional Security System Multinational Coast Guard Unit in the Eastern Caribbean

    Science.gov (United States)

    2012-06-08

    the teaching staff of Staff Group 11 A (Mr Matt Bonnott, Dr Thomas Huber, LTC Andrew McIntyre) and Mr William Knight for officiating, my oral...assist me on this journey. Finally, to my wife Vonette, son Isaiah , daughter Makayla, my mother Muriel (this one is for you), and my friends (too...for the implementation of a new security risk management mechanism to enhance the security of the RSS sub-region. According to Thomas Norman in the

  12. Global Governance: Old and New Issues

    OpenAIRE

    Gary Clyde Hufbauer

    2008-01-01

    This paper opens with a short recollection of the Kiel Week Conference of 2002, recorded in a volume edited by Horst Siebert, titled Global Governance: An Architecture for the World Economy. Assess-ments and forecasts made at that time are scored against subsequent developments. Security relations between the great powers are asserted to define the space for global economic governance. Over the next thirty years, the security context is not likely to provide the same inspiration for global ec...

  13. The Liberal Struggle for Press Freedom

    DEFF Research Database (Denmark)

    Mogensen, Kirsten

    In this paper, the public debate following the re-ligion-motivated assassination of Dutch filmmaker Theo van Gogh in November 2004 is examined. The paper aims at describ-ing religious as well as secular positions in the Danish debate about freedom of speech and press in relation to religious issues....... Historically, the concept of press freedom was linked to a fight for religious freedom in London, as described by Siebert....

  14. Lagunas de saberes. Dios Mangüy San Dionisio del Mar

    DEFF Research Database (Denmark)

    2013-01-01

    short thematic clips for use as didactic material for the teaching of the Indigenous language in local primary schools; - COSTUMBRE Y SABIDURÍAS: A short video by Chiara Bresciani on the preparation of food for festive/ritual events and an 11 mins video by Marta Iannetti on traditional midwifery ("Mi...... ndxuey ikojts - Nuestras parteras"); - FOTOGRAFÍAS: A slideshow of pictures taken in the village, with background music from local composer Obdulio Muriel; - LENGUA VIVA: The digital version of some of the drawings and other materials (two rhymes, a tale and a recipe) created by the children of local...

  15. Concert club

    CERN Multimedia

    Concert club

    2010-01-01

    CERN MEYRIN (terminus bus 56-CERN) entrée B - bâtiment 500 - amphithéâtre mardi 23 mars 2010 à 20 h 30 Eric Schmid, clarinette Muriel Slatkine, piano Au programme : Danzi, Delibes, Gounod, Lovreglio (Verdi), Poulenc, Rossini, Schubert * * * * * samedi 27 mars 2010 à 20 h 30 « Quart de ton » Orchestre et solistes Au programme : Leung Xiao, Lan www.myspace.com/lecardethon * * * * * Dimanche 28 mars 2010 à 17 h 00 et 19 h 00 Rachel Kolly d’Alba, violon Au programme : Bach, Ysaïe * * * * * mardi 30 mars 2010 à 20 h 30 ...

  16. Humain behavior

    CERN Multimedia

    James,M

    1979-01-01

    Le Dr.Muriel James est ingénieur, conseiller/consultant dans plusieurs commissions (p.ex.justice criminelle au Japon) et universités et est l'auteur de nombreux livres (11) traduits dans plusieurs langues. Le plus connu de ses ouvrages est "Born to win". Dans son exposé elle se réfère à son livre "O.K.Boss" et parle d'un modèle spécifique du comportement humain et de ses qualités essentielles qui est la base de son travail.

  17. Resenha

    Directory of Open Access Journals (Sweden)

    Mauro Figueiredo Brito Júnior

    2018-03-01

    Full Text Available Autora de As desordens da biblioteca (2015, Muriel Pic (1974 é doutora pela l'École des Hautes Etudes em Sciences Sociales e ensina literatura francesa na universidade de Berna, Suíça. É pesquisadora associada ao FNS (Fonds National Suisse de la Recherche Scientifique. Investiga autores como Walter Benjamin, Theodor Adorno, Pierre Jean Jouve e Georges Bataille entre outros da literatura francesa e alemã do século XX. Além da obra analisada nesta resenha, publicou outros livros e artigos sobre literatura ainda não traduzidos no Brasil.

  18. Agreement for depression diagnosis between DSM-IV-TR criteria, three validated scales, oncologist assessment, and psychiatric clinical interview in elderly patients with advanced ovarian cancer

    OpenAIRE

    Rhondali, Wadih; Freyer, Gilles; Adam, Virginie; Filbet, Maril?ne; Derzelle, Martine; Abgrall-Barbry, Gaelle; Bourcelot, Sophie; Machavoine, Jean-Louis; Chomat-Neyraud, Muriel; Gisserot, Olivier; Largillier, R?mi; Le Rol, Annick; Priou, Frank; Saltel, Pierre; Falandry, Claire

    2015-01-01

    Wadih Rhondali,1 Gilles Freyer,2 Virginie Adam,3 Marilène Filbet,4 Martine Derzelle,5 Gaelle Abgrall-Barbry,6 Sophie Bourcelot,7 Jean-Louis Machavoine,8 Muriel Chomat-Neyraud,9 Olivier Gisserot,10 Rémi Largillier,11 Annick Le Rol,12 Frank Priou,13 Pierre Saltel,14 Claire Falandry15 1Clinique Mon Repos, Clinea, Marseille, France; 2Medical Oncology Unit, Centre Hospitalier Lyon Sud, Université Lyon 1, Pierre-Benite, France; 3Institut de Cancérologie ...

  19. Pictures of the month

    CERN Multimedia

    Claudia Marcelloni

    Dino De Paoli (top) and Franck Bais (bottom) from CERN and members of the ATLAS experimental area management team installing the TX1S monoblock shielding "nose" from inside the LHC tunnel. Steve Goldfarb and Connie Potter, both ATLAS members doubling as lead singers of the Canettes Blues Band in their spare time, during a concert at Mr Pickwick's Pub in Geneva on March 23rd. Any cooler and you freeze! Muriel is utterly disheartened that she has not yet received any mail from ATLAS e-news readers for her "Opinion and Comments" section....

  20. Smile designing for cleft lip and palate patient: The prosthodontic approach

    Directory of Open Access Journals (Sweden)

    Karuna Gajanan Pawashe

    2017-01-01

    Full Text Available The case report describes smile designing of a 22-year-old male patient who was surgically operated for unilateral cleft lip (left side with Andrew's Bridge system. It is composed of two components: Fixed component (retainers on abutments joined by bar and removable component. The patient exhibited maxillary anterior defect (Siebert's Class-III anterior ridge defect, teeth transposition, increased mesiodistal edentulous space, bilaterally missing lateral incisor. When there is a limitation of bone grafting/surgical augmentation, alternative treatment modalities such as removable partial dentures, fixed partial dentures with gingival porcelain and/or fixed-removable partial dentures known as Andrew's bridge are indicated.

  1. The Essence of Cooperation: Establishing a Framework for Success in Military Regimes

    Science.gov (United States)

    2015-06-01

    USAF) or foreign customers.4 Consequently, on 12 September 2006, 13 NATO countries signed a Letter of Intent (LOI) to launch contract negotiations...25% and schedule delays were at 3-4 years with no certain delivery schedule. See Bjoern Siebert, “Too Big to Fail: The A400M Bail Out,” RUSI...Defence Systems, (February 2010), 78-81. 4 Tirpak, “C-17s in Hungary,” 39. 5 See Letter of Confirmation in Annex B of Memorandum of Understanding

  2. RLE Progress Report Number 122.

    Science.gov (United States)

    1980-01-01

    Hosford R.M. Brown Prof. W.M. Siebert Dr. N.Y.S. Kiang A.H. Crist Prof. T.F. Weiss Dr. M.J. Mulroy D.C. Galley Dr. T.R. Bourk Dr. W.M. Rabinowitz E.M. Marr...Research Scientists Durlach, Nathaniel I. Klatt, Dennis H. Principal Research Scientists Colburn, H. Steven Melngailis, John Lecturers Bourk , Terrance...R. Gruberg, Edward R. Plotkin, George M. Widin, Gregory P. Research Staff Antonsen, Thomas M., Jr. Englade, Ronald C. Hunnicutt, M. Sharon Barrett

  3. How do you like them presentations?

    CERN Multimedia

    Muriel

    Muriel noticed a few small annoyances during some ATLAS meetings. Therefore, Mumu has kindly designed a simple quiz to help raise awareness about frequent mistakes made during presentations. Muriel hard at work, preparing this quiz. Where should you be looking during your talk? The floor The screen The highest-ranking member of the ATLAS management in attendance Where else could I be looking? Match the text with the corresponding speaker type The bored speaker The mumbler The ill-prepared The organizationally-challenged a) "euh... euh... euh.. mmmh.... euh... euh.. well... euh..." b) "From the diagram I showed in slide 13, you can now see from slide 6 why we end-up with such a mess in slide 25." c) "mumnam mumnam mumnam ATLAS mumble mumble data mananman ten manam manmanm... " d) "As I have already shown 16 times in other equally interesting talks..." Replace this sentence in its appropriate context: The RAT and the CAT, two AMIs of bad ORACLE, DIAL a CONDOR above the COOL SEAL PO...

  4. Leadership and innovation in nursing seen through a historical lens.

    Science.gov (United States)

    Harris, Ruth; Bennett, Janette; Ross, Fiona

    2014-07-01

    To explore nurses' archived accounts of Matron Muriel Powell's management and leadership style and the impact of this on the implementation and sustainability of innovation in the workplace. In popular discourse, the matron has become an emblem of leadership. Although the title disappeared in the UK in the late 1960s as part of the re-organization recommended by the Salmon Report, it re-appeared in 2002 in an attempt to improve care standards by reasserting a strong nursing presence and clinical leadership role. Secondary data analysis using qualitative thematic analysis. This paper draws on interview data held in the 'Nurses Voices' archive. The interview transcripts of 132 nurses who trained or worked at St George's hospital in 1920-1980 were analysed in depth between March 2011-January 2012 and themes were generated inductively by grouping together emergent codes in the data with similar meaning. Looking back, the nurses recalled strong memories of the leadership of Matron Powell. Her presence emerged as a significant influence throughout the interviews. Two resonant themes were identified: innovation and open communication. Through her visibility and direct access with patients and staff, Dame Muriel Powell showed what we would now call transformative leadership qualities. Her leadership created a culture of open communication and innovation that initiated change in the organization and the nursing workforce. Looking back and learning from historical figures can deepen understanding and provide pointers for the nurse leaders of today. © 2013 John Wiley & Sons Ltd.

  5. Reversibility and irreversibility from an initial value formulation

    International Nuclear Information System (INIS)

    Muriel, A.

    2013-01-01

    From a time evolution equation for the single particle distribution function derived from the N-particle distribution function (A. Muriel, M. Dresden, Physica D 101 (1997) 297), an exact solution for the 3D Navier–Stokes equation – an old problem – has been found (A. Muriel, Results Phys. 1 (2011) 2). In this Letter, a second exact conclusion from the above-mentioned work is presented. We analyze the time symmetry properties of a formal, exact solution for the single-particle distribution function contracted from the many-body Liouville equation. This analysis must be done because group theoretic results on time reversal symmetry of the full Liouville equation (E.C.G. Sudarshan, N. Mukunda, Classical Mechanics: A Modern Perspective, Wiley, 1974). no longer applies automatically to the single particle distribution function contracted from the formal solution of the N-body Liouville equation. We find the following result: if the initial momentum distribution is even in the momentum, the single particle distribution is reversible. If there is any asymmetry in the initial momentum distribution, no matter how small, the system is irreversible.

  6. En quoi la narration dans le romanL’Élégance du hérisson permet de bien rendre lamétaphore du « bocal à poissons »? : Une analyse narratologique

    OpenAIRE

    Racine, Sylvain

    2015-01-01

    Sur la base des travaux de Gérard Genette, en particulier Figures III, uneanalyse narratologique du roman L’Élégance du hérisson (2006) de l’auteur MurielBarbery a été effectuée afin de comprendre les liens qu’il y a entre les spécificités dumode narratif et leurs effets sur l’espace du récit, soit « le bocal à poissons », unemétaphore importante du roman. Ultimement nous répondons à la question suivante :En quoi la narration dans le roman L’Élégance du hérisson permet-elle de bien rendrela m...

  7. From Allá en el Rancho Grande to Lola la trailera: social mobility

    Directory of Open Access Journals (Sweden)

    Aurelio de los Reyes

    2016-04-01

    Full Text Available The text deals with both horizontal and vertical social mobility in the Mexican films Allá en el Rancho Grande (1936, Fernando de Fuentes, Por la puerta falsa (1950, Fernando de Fuentes, Nosotras las taquígrafas (1950, Emilio Gómez Muriel, El río y la muerte (1954, Luis Buñuel, three films by Emilio Fernández: Victimas del pecado (1950, Salón México (1948 and Las abandonadas (1944, two films by Ismael Rodríguez: La Cucaracha (1958 and Del rancho a la televisión (1952 and Lola la trailera (1984, Raúl Fernández, which speaks to the country’s transition from an agricultural to an industrial economy.

  8. Dose equivalent response of personal neutron dosemeters as a function of angle

    International Nuclear Information System (INIS)

    Tanner, J.E.; McDonald, J.C.; Stewart, R.D.; Wernli, C.

    1997-01-01

    The measured and calculated dose equivalent response as a function of angle has been examined for an albedo-type thermoluminescence dosemeter (TLD) that was exposed to unmoderated and D 2 O-moderated 252 Cf neutron sources while mounted on a 40 x 40 15 cm 3 polymethylmethacrylate phantom. The dosemeter used in this study is similar to many neutron personal dosemeters currently in use. The detailed construction of the dosemeter was modelled, and the dose equivalent response was calculated, using the MCNP code. Good agreement was found between the measured and calculated values of the relative dose equivalent angular response for the TLD albedo dosemeter. The relative dose equivalent angular response was also compared with the values of directional and personal dose equivalent as a function of angle published by Siebert and Schuhmacher. (author)

  9. Static and dynamic 3 dimensional studies of water in soil using computed tomographic scanning

    International Nuclear Information System (INIS)

    Crestana, S.; Mascarenhas, S.; Pozzi-Mucelli, R.S.

    1984-03-01

    Previous work of Petrovic, Siebert and Rieke demonstrated the possibility of using X-ray transmission computed tomography (CT) scanning for soil bulk density analysis in soil. We show in the present work that CT can also be used for the measurement of water content in soil. In our case we also show that CT can be applied to measure and follow dynamically the motion of water in soil in 3-dimensions. Further, more inhomogeneities of water content and motion in soil can be observed with this technique. Using a third generation CT scanner several different techniques can be applied such as differential, real time and spatial distribution scanning modes. A linear dependence was demonstrated for the Hounsfield Units (HU) used in CT and water content. The use of CT for water content and motion in soil in 3-dimensions opens new possibilities in this area of investigations. (author)

  10. The thermotidal exciting function for water vapour absorption of solar radiation

    Directory of Open Access Journals (Sweden)

    M. BONAFEDE

    1976-06-01

    Full Text Available The thermotidal exciting function J is considered, for
    the absorption of solar radiation by water vapour, according to the model
    derived by Siebert. The Mugge-Moller formula for water vapour absorption
    is integrated numerically, using experimental data for the water vapour
    concentration in the troposphere and the stratosphere. It appears that
    Siebort's formula is a reasonable approximation at low tropospheric levels
    but it dramatically overestimates the water vapour thermotidal heating
    in the upper troposphere and in the stratosphere. It seems thus possible
    that, if the correct vertical profile is employed for J , the amplitudes and
    phases of the diurnal temperature oscillations and of the tidal wind speeds
    may suffer significant changes from those previously calculated and possibly explain the three hours delay of the observed phases from the computed values.

  11. Calabi-Yau varieties: arithmetic, geometry and physics lecture notes on concentrated graduate courses

    CERN Document Server

    Schütt, Matthias; Yui, Noriko

    2015-01-01

    This volume presents a lively introduction to the rapidly developing and vast research areas surrounding Calabi–Yau varieties and string theory. With its coverage of the various perspectives of a wide area of topics such as Hodge theory, Gross–Siebert program, moduli problems, toric approach, and arithmetic aspects, the book gives a comprehensive overview of the current streams of mathematical research in the area. The contributions in this book are based on lectures that took place during workshops with the following thematic titles: “Modular Forms Around String Theory,” “Enumerative Geometry and Calabi–Yau Varieties,” “Physics Around Mirror Symmetry,” “Hodge Theory in String Theory.” The book is ideal for graduate students and researchers learning about Calabi–Yau varieties as well as physics students and string theorists who wish to learn the mathematics behind these varieties.

  12. Homological mirror symmetry and tropical geometry

    CERN Document Server

    Catanese, Fabrizio; Kontsevich, Maxim; Pantev, Tony; Soibelman, Yan; Zharkov, Ilia

    2014-01-01

    The relationship between Tropical Geometry and Mirror Symmetry goes back to the work of Kontsevich and Y. Soibelman (2000), who applied methods of non-archimedean geometry (in particular, tropical curves) to Homological Mirror Symmetry. In combination with the subsequent work of Mikhalkin on the “tropical” approach to Gromov-Witten theory, and the work of Gross and Siebert, Tropical Geometry has now become a powerful tool. Homological Mirror Symmetry is the area of mathematics concentrated around several categorical equivalences connecting symplectic and holomorphic (or algebraic) geometry. The central ideas first appeared in the work of Maxim Kontsevich (1993). Roughly speaking, the subject can be approached in two ways: either one uses Lagrangian torus fibrations of Calabi-Yau manifolds (the so-called Strominger-Yau-Zaslow picture, further developed by Kontsevich and Soibelman) or one uses Lefschetz fibrations of symplectic manifolds (suggested by Kontsevich and further developed by Seidel). Tropical Ge...

  13. Molybdenum isotopes in modern marine hydrothermal Fe/Mn deposits: Implications for Archean and Paleoproterozoic Mo cycles

    Science.gov (United States)

    Goto, K. T.; Hein, J. R.; Shimoda, G.; Aoki, S.; Ishikawa, A.; Suzuki, K.; Gordon, G. W.; Anbar, A. D.

    2016-12-01

    Molybdenum isotope (δ98/95Mo) variations recorded in Archean and Paleoproterozoic Fe/Mn-rich sediments have been used to constrain ocean redox conditions at the time of deposition (Canfield et al., 2013 PNAS; Planavsky et al., 2014 Nat. Geo.; Kurzweil et al., 2015 GCA). However, except for hydrogenous Fe-Mn crusts (Siebert et al., 2003), δ98/95Mo variation of modern Fe and Mn oxide deposits has been poorly investigated. Marine hydrothermal systems are thought to be the major source of Fe and Mn in Archean and Paleoproterozoic Fe- and Mn-rich sediments. Hence, to accurately interpret Mo isotope data of those ancient sedimentary rocks, it is important to evaluate the possible influence of hydrothermally derived Mo on δ98/95Mo of modern Fe- and Mn-rich sediments. In this study, we analyzed Mo isotopic compositions of one hydrothermal Fe oxide and 15 Mn oxides from five different hydrothermal systems in the modern ocean. The Fe oxide is composed mainly of goethite, and has a δ98/95Mo of 0.7‰, which is 1.4‰ lighter than that of present-day seawater. The observed offset is similar to isotope fractionation observed during adsorption experiments of Mo on goethite (Δ98/95Mogoethite-solution = -1.4 ± 0.5%; Goldberg et al., 2009 GCA). The 15 hydrothermal Mn oxides show large variations in δ98/95Mo ranging from -1.7 to 0.5‰. However, most of the values are similar to those of modern hydrogenous Fe-Mn crusts (Siebert et al., 2003 EPSL), and fall within the range of estimated δ98/95Mo of Mn oxides precipitated from present-day seawater using the isotope offset reported from adsorption experiments (Δ98/95Mo = -2.7 ± 0.3‰; Wasylenki et al., 2008 GCA). These findings indicate that seawater is the dominant source of Mo for modern hydrothermal Fe and Mn deposits. However, the observed large variation indicates that the contribution Mo from local hydrothermal systems is not negligible. The oceanic Mo inventory during the Archean and Paleoproterozoic is thought to be

  14. Changing the Subject: Archives, Technology, and Radical Counter-Narratives of Peace

    Directory of Open Access Journals (Sweden)

    J. Ashley Foster

    2016-07-01

    Full Text Available This article argues that performing the recovery of pacifist art and actions through archival research of the modernist era encourages students to engage in radical ethical inquiry.  Based on four sections of a writing class at Haverford College, this article walks the reader through the construction of a student digital humanities and special collections exhibition, Testimonies in Art & Action: Igniting Pacifism in the Face of Total War, which ran from October 6 to December 11, 2015 in Haverford College’s Magill Library.  The exhibition placed archival materials in conversation with the major modernist pacifist documentary projects of Langston Hughes’s Spanish Civil War poetry and dispatches, Muriel Rukeyser’s “Mediterranean,” Pablo Picasso’s Guernica, and Virginia Woolf’s Three Guineas.  This undertaking was driven by the questions, “How does one respond ethically to total war?” and “How can archival and special collections research do the works of peace?” Built around the work of these classes and materials from Haverford’s Quaker & Special Collections, Testimonies in Art & Action allowed students to deeply interrogate a variety of pacifisms and become producers of a critical discourse that challenges the status quo position that violence is perpetually necessary and the most important aspect of world history.

  15. Best pictures of the month

    CERN Multimedia

    Claudia Marcelloni de Oliveira

    The last sector of the Big Muon Wheels was brought to the cavern in the morning of September 20... ... installed on one of the Big Muon Wheels during the same afternoon... ... just in time to sqeeze lots of people in between two of the all-completed Big Muon Wheels on the 21st of September to celebrate the installation of the last sector. Installation of the first ATLAS small wheel in building 191 on September 10. Some of the people involved in the construction and installation of the chambers on the first ATLAS small wheel in building 191 celebrating its completion on September 20. After hearing that the rock band The Police played in Geneva last month, Muriel got inspired and decided to become a rock star, just like one of her favorites, Keith Richards from the Rolling Stones. Special accomplishment of the month: (top) Martina Hurwitz (#908) and Monica Dunford (680), both from the Chicago University group, completed the Lausanne Marathon on October 21 in 4h 4...

  16. The treatment of gender and time in Winterson’s and Spark’s novels

    Directory of Open Access Journals (Sweden)

    Andreja Radetič

    2009-12-01

    Full Text Available Both Jeanette Winterson and Muriel Spark try to challenge and overcome culturally constructed binary oppositions between two genders. Winterson imposes femininity on men and masculinity on women. She denies traditional gender roles. In her novels, men and heterosexuality are marginalized or even overlooked. Both Winterson and Spark portray women, who are active, independent and domineering; they reject marriage, are educated, live on their own and are in control of their lives. The main difference between Winterson’s and Spark’s women is that the former are heroines and the latter are victims (either of themselves or the others. Both authors deny traditional notion of time and history. Winterson useshistory to explore the present. She magnifies the individual’s role in history-making and challenges the traditional notion of history being male-constructed. She gives a woman a role in history-making. Both Spark’s and Winetrson’s novels are set anti-linearly with the use of prolepses and antilepses.

  17. Selected pictures of the month

    CERN Multimedia

    Claudia Marcelloni de Oliveira

    View of a single MDT Big Wheel (on side A in UX15 cavern) taken during its last movement immediately after being assembled and just before being connected to the neighbouring TGC1 wheel. Assembly work on the Cathode Strip Chambers on Small Wheel C in building 190. Connecting the services for the Cathode Strip Chambers. The installation of the optical fibers for the readout of the Cathode Strip Chambers on Small Weel C by the Irvine group. Best from our archives: View of the End Cap Calorimeter and TGC big wheel from the Cryostat side A of ATLAS cavern taken on 22 May 2007. The picture above was taken from the platform in the middle, between the Cryostat and the End-Cap. Muriel hopes you all had a great vacation. She herself had a wonderful time sailing in Galicia (North Western Spain). She can be seen here wearing the traditional dress offered to her by "Los Amigos de las Dornas" (Friends of the Dornas -traditional sailing boats used for fishing) - when she became ...

  18. The Rat Race

    CERN Multimedia

    Stephen Haywood

    Dear Muriel, Being an animal, you are probably more familiar with rats than most of us. Yet it seems to me that our Community (not just ATLAS) is stuck in a huge "rat race". I am somewhat mystified as to how we have got ourselves into this and I wonder whether you or your readers could explain this - I give my own observations below. In HEP and ATLAS specifically, we are all working long hours and we are all becoming exhausted. There are people at Point 1 who are working day and night, every day of the week; there are people writing software who send emails round the clock, including weekends. It is one thing to have bursts of activity which require us to put in some longer hours, but in ATLAS, the bursts last months or years. I have been on ATLAS 14 years and it has felt like one endless rush. Why do we do this? We are all highly motivated, we love our work and want to succeed individually and collectively. We are parts of various teams, and we do not want to let the side down. We worked hard at school an...

  19. ID Barrel installed in cryostat

    CERN Multimedia

    Apsimon, R.; Romaniouk, A.

    Wednesday 23rd August was a memorable day for the Inner Detector community as they witnessed the transport and installation of the central part of the inner detector (ID-barrel) into the ATLAS detector. Many members of the collaboration gathered to witness this moment at Point 1. After years of design, construction and commissioning, the outer two detectors (TRT and SCT) of the ID barrel were moved from the SR1 cleanroom to the ATLAS cavern. The barrel was moved across the car park from building 2175 to SX1. Although only a journey of about 100 metres, this required weeks of planning and some degree of luck as far as the weather was concerned. Accelerometers were fitted to the barrel to provide real-time monitoring and no values greater than 0.1 g were recorded, fully satisfying the transport specification for this extremely precise and fragile detector. Muriel, despite her fear of heights, bravely volunteered to keep a close eye on the detector. Swapping cranes to cross the entire parking lot, while Mur...

  20. Impressions from the ATLAS Overview Week in Stockholm

    CERN Document Server

    De Jong, P.; Gowdy, S.

    2006-01-01

    Paul de Jong: "What a very nice city Stockholm in the summer turned out to be! The architecture, the relaxed style of the city and its islands and bridges, the terraces with people out on the streets until late at night made this a special trip. We visited many cool and trendy places, unfortunately many of those places are probably now a lot less cool and trendy after visits of so many physicists in shorts and white socks in sandals. A big applause for the organizers for a fine meeting, and getting us into the Stockholm city hall and the superb Wasa museum. (left) The Golden room of Stockholm City Hall. (right) Muriel was not the only one in the room entertaining noble dreams during the reception in the Golden Room of the Stockholm City Hall... ATLAS is a monstrously complicated piece of apparatus. It will be very impressive when it is finished and works, but there are so many places where things can go wrong. If I must name a single highlight of the week: I found the technical coordination of t...

  1. Energetics of the terrestrial bow shock

    Science.gov (United States)

    Hamrin, Maria; Gunell, Herbert; Norqvist, Patrik

    2017-04-01

    The solar wind is the primary energy source for the magnetospheric energy budget. Energy can enter through the magnetopause both as kinetic energy (plasma entering via e.g. magnetic reconnection and impulsive penetration) and as electromagnetic energy (e.g. by the conversion of solar wind kinetic energy into electromagnetic energy in magnetopause generators). However, energy is extracted from the solar wind already at the bow shock, before it encounters the terrestrial magnetopause. At the bow shock the supersonic solar wind is slowed down and heated, and the region near the bow shock is known to host many complex processes, including the accelerating of particles and the generation of waves. The processes at and near the bow shock can be discussed in terms of energetics: In a generator (load) process kinetic energy is converted to (from) electromagnetic energy. Bow shock regions where the solar wind is decelerated correspond to generators, while regions where particles are energized (accelerated and heated) correspond to loads. Recently, it has been suggested that currents from the bow shock generator should flow across the magnetosheath and connect to the magnetospause current systems [Siebert and Siscoe, 2002; Lopez et al., 2011]. In this study we use data from the Magnetospheric MultiScale (MMS) mission to investigate the energetics of the bow shock and the current closure, and we compare with the MHD simulations of Lopez et al., 2011.

  2. A Conversation with Martin Stannard and Barbara Cooke

    Directory of Open Access Journals (Sweden)

    Annabel Williams

    2016-10-01

    Full Text Available Martin Stannard is Professor of Modern English Literature at the University of Leicester. He read for his first degree in English at Warwick (1967-70, before taking an MA at Sussex University, and a DPhil at Oxford. Professor Stannard’s two-volume literary biography of Evelyn Waugh (1986, 1992, and his biography of Muriel Spark (2009 are essential reading for Waugh and Spark scholars, and are each studies in the value of historical contextualisation for appreciating the literary oeuvre of a writer. Stannard’s 1995 Norton Critical Edition of Ford Madox Ford’s modernist novel, The Good Soldier, similarly brings context to bear through his rigorous textual editing, annotation and critical apparatus. Stannard is currently the Principal Investigator for the Complete Works of Evelyn Waugh project, which is supported by a grant of  £822,000 from the AHRC, and which will see Oxford University Press publish 43 scholarly edition volumes of Waugh – the first of which appears next year. This year marks the fiftieth anniversary of Waugh’s death. Dr Barbara Cooke also teaches at the School of English at the University of Leicester. She received a BA and MA from Warwick (dates, and a PhD in Creative and Critical writing from the University of East Anglia for her interdisciplinary thesis Oil Men: the Twinned Lives of Arnold Wilson and Morris Young. Dr. Cooke is Research Associate for the Complete Works of Evelyn Waugh, providing a vital link between the project's 23 editors, of which she is one, editing Waugh’s autobiography A Little Learning (1964.

  3. Occupational balance: exploring the relationships among daily occupations and their influence on well-being.

    Science.gov (United States)

    Backman, Catherine L

    2004-10-01

    In this lecture, I have reviewed theoretical discussions and definitions of occupational balance, findings from selected studies, and highlighted some methods for measuring aspects of occupational balance. Are any of these ideas directly applicable to occupational therapy practice, education and research? Consider the hassles of everyday life, and add the complicating factors of illness, injury, disability, and limited income. Life, and the pursuit of necessary, desirable and obligatory occupations, can become overwhelming. Given that occupational therapists aim to enable individuals, regardless of ability, to successfully engage in a range of occupations, the answer to the question is yes. Furthering our understanding of occupational balance can improve our ability to serve individual clients and society. In 2001, Fearing stated in her Muriel Driver Memorial Lecture: We will not only recognize and value the skill of maintaining balance, our own and that of our clients, but we will live it. Balance will not be viewed as a set of scales that has equal parts such as work on one side and play on the other but rather the kind of balance that comes from being centred so that we act from a stable base. From that stable base, we will gain a keen sensitivity to rhythm--knowing when to move and when to let go. (Fearing, 2001 pp. 214-215) Perhaps these reflections have added a little coherence to the study of occupational balance. Occupational balance is a relative state, recognizable by a happy or pleasant integration of life activities and demands. There are indicators of imbalance, more so than tangible ways to measure it, and once recognized occupational therapists have the strategies to help restore a sense of occupational balance. Given our collective history and skill in client-centred practice, occupational therapists are capable of both advancing this line of inquiry and attaining occupational balance for ourselves and our clients.

  4. The organization of LH2 complexes in membranes from Rhodobacter sphaeroides.

    Science.gov (United States)

    Olsen, John D; Tucker, Jaimey D; Timney, John A; Qian, Pu; Vassilev, Cvetelin; Hunter, C Neil

    2008-11-07

    The mapping of the photosynthetic membrane of Rhodobacter sphaeroides by atomic force microscopy (AFM) revealed a unique organization of arrays of dimeric reaction center-light harvesting I-PufX (RC-LH1-PufX) core complexes surrounded and interconnected by light-harvesting LH2 complexes (Bahatyrova, S., Frese, R. N., Siebert, C. A., Olsen, J. D., van der Werf, K. O., van Grondelle, R., Niederman, R. A., Bullough, P. A., Otto, C., and Hunter, C. N. (2004) Nature 430, 1058-1062). However, membrane regions consisting solely of LH2 complexes were under-represented in these images because these small, highly curved areas of membrane rendered them difficult to image even using gentle tapping mode AFM and impossible with contact mode AFM. We report AFM imaging of membranes prepared from a mutant of R. sphaeroides, DPF2G, that synthesizes only the LH2 complexes, which assembles spherical intracytoplasmic membrane vesicles of approximately 53 nm diameter in vivo. By opening these vesicles and adsorbing them onto mica to form small, LH2-only membranes for the first time. The transition from highly curved vesicle to the planar sheet is accompanied by a change in the packing of the LH2 complexes such that approximately half of the complexes are raised off the mica surface by approximately 1 nm relative to the rest. This vertical displacement produces a very regular corrugated appearance of the planar membrane sheets. Analysis of the topographs was used to measure the distances and angles between the complexes. These data are used to model the organization of LH2 complexes in the original, curved membrane. The implications of this architecture for the light harvesting function and diffusion of quinones in native membranes of R. sphaeroides are discussed.

  5. VizieR Online Data Catalog: ROSAT detected quasars. II. (Yuan+ 1998)

    Science.gov (United States)

    Yuan, W.; Brinkmann, W.; Siebert, J.; Voges, W.

    1997-11-01

    We have compiled a sample of all radio-quiet quasars or quasars without radio detection from the Veron-Cetty - Veron catalogue (1993, VV93, Cat. ) detected by ROSAT in the ALL-SKY SURVEY (RASS, Voges 1992, in Proc. of the ISY Conference `Space Science', ESA ISY-3, ESA Publications, p.9, See Cat. ), as targets of pointed observations, or as serendipitous sources from pointed observations publicly available from the ROSAT point source catalogue (ROSAT-SRC, Voges et al. 1995, Cat. ). For all sources we used the results of the Standard Analysis Software System (SASS, Voges et al. 1992, in Proc. of the ISY Conference `Space Science', ESA ISY-3, ESA Publications, p.223), employing the most recent processing for the Survey data (RASS-II, Voges et al. 1996, Cat. ). The total number of quasars is 846. 69 of the radio-quiet objects with radio detections have already been presented in a previous paper (Brinkmann, Yuan, & Siebert 1997, Cat. ) using the RASS-I results. 17 objects were found to be radio-loud from recent radio surveys and were marked in the table. When available, the power law photon indices and the corresponding absorption column densities (NH) were estimated from the two hardness ratios given by the SASS, both with free fitted NH and for Galactic absorption. The unabsorbed X-ray flux densities in the ROSAT band (0.1-2.4keV) were calculated from the count rates using the energy to counts conversion factor for power law spectra and Galactic absorption. As the photon index we used the value obtained for the individual source if the estimated 1-σ error is smaller than 0.5, otherwise we used the redshift-dependent mean value (see the paper for details). (1 data file).

  6. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2008-12-01

    Full Text Available Maximilian C. Forte; Ruins of Absence, Presence of Caribs: (PostColonial Representations of Aboriginality in Trinidad and Tobago (Neil L. Whitehead Nick Nesbitt; Voicing Memory: History and Subjectivity in French Caribbean Literature (H. Adlai Murdoch Camilla Stevens; Family and Identity in Contemporary Cuban and Puerto Rican Drama (Lydia Platón Jonathan Goldberg; Tempest in the Caribbean (Jerry Brotton Michael Chanan; Cuban Cinema (Tamara L. Falicov Gemma Tang Nain, Barbara Bailey (eds.; Gender Equality in the Caribbean: Reality or Illusion (A. Lynn Bolles Ernesto Sagás, Sintia E. Molina (eds.; Dominican Migration: Transnational Perspectives (Rosemary Polanco Christine M. Du Bois; Images of West Indian Immigrants in Mass Media: The Struggle for a Positive Ethnic Reputation (Dwaine Plaza Luis Raúl Cámara Fuertes; The Phenomenon of Puerto Rican Voting (Annabelle Conroy Philip Gould; Barbaric Traffic: Commerce and Antislavery in the Eighteenth-Century Atlantic World (William A. Pettigrew Laurent Dubois; Avengers of the New World: The Story of the Haitian Revolution (Yvonne Fabella Sibylle Fischer; Modernity Disavowed: Haiti and the Cultures of Slavery in the Age of Revolution (Ashli White Philip D. Morgan, Sean Hawkins (eds.; Black Experience and the British Empire (James Walvin Richard Smith; Jamaican Volunteers in the First World War: Race, Masculinity and the Development of National Consciousness (Linden Lewis Muriel McAvoy; Sugar Baron: Manuel Rionda and the Fortunes of Pre-Castro Cuba (Richard Sicotte Ned Sublette; Cuba and Its Music: From the First Drums to the Mambo (Pedro Pérez Sarduy Frances Negrón-Muntaner; Boricua Pop: Puerto Ricans and the Latinization of American Culture (Halbert Barton Gordon Rohlehr; A Scuffling of Islands: Essays on Calypso (Stephen Stuempfle Shannon Dudley; Carnival Music in Trinidad: Experiencing Music, Expressing Culture (Donald R. Hill Jean

  7. Comparative evaluation of 64-slice CT angiography and digital subtraction angiography in assessing the cervicocranial vasculature

    Directory of Open Access Journals (Sweden)

    Randolf Klingebiel

    2008-08-01

    Full Text Available Randolf Klingebiel1, Max Kentenich3, Hans-Christian Bauknecht3, Florian Masuhr2, Eberhard Siebert1, Markus Busch2, Georg Bohner11Department of Neuroradiology, 2Department of Neurology, 3Department of Radiology, Charité Universitary Medicine Berlin, GermanyBackground: Noninvasive 64-slice computed tomography angiography (64-MSCTA closely approximates conventional catheter angiography (DSA in terms of detail resolution. Objective: Retrospective evaluation of cervicocranial (cc 64-MSCTA in comparison with DSA in patients with presumptive cc vascular disorders.Material and methods: Twenty-four 64-MSCTA studies (32 mm detector width, slice thickness 0.5 mm, 120 kv, 150 mAs, pitch 0.75 of patients with presumptive cc vascular pathology (13 men, 11 women, mean age 38.3 ± 11.3 yrs, range 19–54 yrs were assessed in comparison with DSA studies without abnormal findings in age-matched patients (11 men, 13 women, mean age 39.7 ± 11.9 yrs, range 18–54 yrs. Study readings were performed in a blinded manner by two neuroradiologists with respect to image quality and assessibility of various cc vascular segments by using a five-point scale. Radiation exposure was calculated for 64-MSCTA.Results: Each reader assessed 384/528 different vessel segments (64-MSCTA/DSA. Superior image quality was attributed to DSA with respect to the C1 ICA–C6 ICA, A3 ACA, and P3 PCA segments as well the AICA and SCA. 64-MSCTA was scored superior for C7 ICA and V4 VA segments. A significantly increased number of nonassessable V2- and V3 VA segments in DSA studies was noted. The effective dose for 64-MSCTA amounted to 2.2 mSv.Conclusions: 64-MSCTA provides near-equivalent diagnostic information of the cc vasculature as compared with DSA. According to our results, DSA should be considered primarily when peripheral vessels (A3/P3 or ICA segments close to the skull base (C2-5 are of interest, such as in primary angiitis or stenoocclusive ICA disease, respectively.Keywords: CT

  8. 3D Coupled Thermal-Hydraulic Model of the Lower Yarmouk Gorge, Jordan Rift Valley

    Science.gov (United States)

    Walther, M.; Magri, F.; Inbar, N.; Möller, P.; Raggad, M.; Rödiger, T.; Rosenthal, E.; Shentsis, I.; Siebert, C.; Volpi, G.

    2017-12-01

    diger, T., Rosenthal, E., Siebert, C., 2016. 2D and 3D coexisting modes of thermal convection in fractured hydrothermal systems - Implications for transboundary flow in the Lower Yarmouk Gorge. Marine and Petroleum Geology 78, 750-758.

  9. A volatile-rich Earth's core inferred from melting temperature of core materials

    Science.gov (United States)

    Morard, G.; Andrault, D.; Antonangeli, D.; Nakajima, Y.; Auzende, A. L.; Boulard, E.; Clark, A. N.; Lord, O. T.; Cervera, S.; Siebert, J.; Garbarino, G.; Svitlyk, V.; Mezouar, M.

    2016-12-01

    Planetary cores are mainly constituted of iron and nickel, alloyed with lighter elements (Si, O, C, S or H). Understanding how these elements affect the physical and chemical properties of solid and liquid iron provides stringent constraints on the composition of the Earth's core. In particular, melting curves of iron alloys are key parameter to establish the temperature profile in the Earth's core, and to asses the potential occurrence of partial melting at the Core-Mantle Boundary. Core formation models based on metal-silicate equilibration suggest that Si and O are the major light element components1-4, while the abundance of other elements such as S, C and H is constrained by arguments based on their volatility during planetary accretion5,6. Each compositional model implies a specific thermal state for the core, due to the different effect that light elements have on the melting behaviour of Fe. We recently measured melting temperatures in Fe-C and Fe-O systems at high pressures, which complete the data sets available both for pure Fe7 and other binary alloys8. Compositional models with an O- and Si-rich outer core are suggested to be compatible with seismological constraints on density and sound velocity9. However, their crystallization temperatures of 3650-4050 K at the CMB pressure of 136 GPa are very close to, if not higher than the melting temperature of the silicate mantle and yet mantle melting above the CMB is not a ubiquitous feature. This observation requires significant amounts of volatile elements (S, C or H) in the outer core to further reduce the crystallisation temperature of the core alloy below that of the lower mantle. References 1. Wood, B. J., et al Nature 441, 825-833 (2006). 2. Siebert, J., et al Science 339, 1194-7 (2013). 3. Corgne, A., et al Earth Planet. Sc. Lett. 288, 108-114 (2009). 4. Fischer, R. a. et al. Geochim. Cosmochim. Acta 167, 177-194 (2015). 5. Dreibus, G. & Palme, H. Geochim. Cosmochim. Acta 60, 1125-1130 (1995). 6. Mc

  10. Sensitivity analysis of hydraulic and thermal parameters inducing anomalous heat flow in the Lower Yarmouk Gorge

    Science.gov (United States)

    Goretzki, Nora; Inbar, Nimrod; Kühn, Michael; Möller, Peter; Rosenthal, Eliyahu; Schneider, Michael; Siebert, Christian; Magri, Fabien

    2016-04-01

    The Lower Yarmouk Gorge, at the border between Israel and Jordan, is characterized by an anomalous temperature gradient of 46 °C/km. Numerical simulations of thermally-driven flow show that ascending thermal waters are the result of mixed convection, i.e. the interaction between the regional flow from the surrounding heights and buoyant flow within permeable faults [1]. Those models were calibrated against available temperature logs by running several forward problems (FP), with a classic "trial and error" method. In the present study, inverse problems (IP) are applied to find alternative parameter distributions that also lead to the observed thermal anomalies. The investigated physical parameters are hydraulic conductivity and thermal conductivity. To solve the IP, the PEST® code [2] is applied via the graphical interface FEPEST® in FEFLOW® [3]. The results show that both hydraulic and thermal conductivity are consistent with the values determined with the trial and error calibrations, which precede this study. However, the IP indicates that the hydraulic conductivity of the Senonian Paleocene aquitard can be 8.54*10-3 m/d, which is three times lower than the originally estimated value in [1]. Moreover, the IP suggests that the hydraulic conductivity in the faults can increase locally up to 0.17 m/d. These highly permeable areas can be interpreted as local damage zones at the faults/units intersections. They can act as lateral pathways in the deep aquifers that allow deep outflow of thermal water. This presentation provides an example about the application of FP and IP to infer a wide range of parameter values that reproduce observed environmental issues. [1] Magri F, Inbar N, Siebert C, Rosenthal E, Guttman J, Möller P (2015) Transient simulations of large-scale hydrogeological processes causing temperature and salinity anomalies in the Tiberias Basin. Journal of Hydrology, 520, 342-355 [2] Doherty J (2010) PEST: Model-Independent Parameter Estimation. user

  11. Birmingham COPD Cohort: a cross-sectional analysis of the factors associated with the likelihood of being in paid employment among people with COPD

    Directory of Open Access Journals (Sweden)

    Rai KK

    2017-01-01

    Full Text Available Kiran K Rai,1 Rachel E Jordan,1 W Stanley Siebert,2 Steven S Sadhra,3 David A Fitzmaurice,1 Alice J Sitch,1 Jon G Ayres,1,3 Peymané Adab1 1Institute of Applied Health Research, 2The Department of Business and Labour Economics, 3Institute of Clinical Sciences, University of Birmingham, Edgbaston, Birmingham, UK Background: Employment rates among those with chronic obstructive pulmonary disease (COPD are lower than those without COPD, but little is known about the factors that affect COPD patients’ ability to work. Methods: Multivariable analysis of the Birmingham COPD Cohort Study baseline data was used to assess the associations between lifestyle, clinical, and occupational characteristics and likelihood of being in paid employment among working-age COPD patients. Results: In total, 608 of 1,889 COPD participants were of working age, of whom 248 (40.8% were in work. Older age (60–64 years vs 30–49 years: odds ratio [OR] =0.28; 95% confidence interval [CI] =0.12–0.65, lower educational level (no formal qualification vs degree/higher level: OR =0.43; 95% CI =0.19–0.97, poorer prognostic score (highest vs lowest quartile of modified body mass index, airflow obstruction, dyspnea, and exercise (BODE score: OR =0.10; 95% CI =0.03–0.33, and history of high occupational exposure to vapors, gases, dusts, or fumes (VGDF; high VGDF vs no VGDF exposure: OR =0.32; 95% CI =0.12–0.85 were associated with a lower probability of being employed. Only the degree of breathlessness of BODE was significantly associated with employment. Conclusion: This is the first study to comprehensively assess the characteristics associated with employment in a community sample of people with COPD. Future interventions should focus on managing breathlessness and reducing occupational exposures to VGDF to improve the work capability among those with COPD. Keywords: chronic obstructive pulmonary disease, work, employed, breathlessness, severity, VGDF, UK

  12. Adherence to AHA Guidelines When Adapted for Augmented Reality Glasses for Assisted Pediatric Cardiopulmonary Resuscitation: A Randomized Controlled Trial.

    Science.gov (United States)

    Siebert, Johan N; Ehrler, Frederic; Gervaix, Alain; Haddad, Kevin; Lacroix, Laurence; Schrurs, Philippe; Sahin, Ayhan; Lovis, Christian; Manzano, Sergio

    2017-05-29

    critical resuscitation endpoints and drug dose delivery were not improved using AR glasses. However, errors and deviations were significantly reduced in terms of defibrillation doses when compared with the use of the PALS pocket reference cards. In a total of 40 defibrillation attempts, residents not wearing AR glasses used wrong doses in 65% (26/40) of cases, including 21 shock overdoses >100 J, for a cumulative defibrillation dose of 18.7 Joules per kg. These errors were reduced by 53% (21/40, Presuscitation endpoints when compared with PALS pocket cards. However, they improved adherence and performance among residents in terms of administering the defibrillation doses set by AHA. ©Johan N Siebert, Frederic Ehrler, Alain Gervaix, Kevin Haddad, Laurence Lacroix, Philippe Schrurs, Ayhan Sahin, Christian Lovis, Sergio Manzano. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 29.05.2017.

  13. A Mobile Device App to Reduce Time to Drug Delivery and Medication Errors During Simulated Pediatric Cardiopulmonary Resuscitation: A Randomized Controlled Trial.

    Science.gov (United States)

    Siebert, Johan N; Ehrler, Frederic; Combescure, Christophe; Lacroix, Laurence; Haddad, Kevin; Sanchez, Oliver; Gervaix, Alain; Lovis, Christian; Manzano, Sergio

    2017-02-01

    391 s (95% CI 298-483), respectively (177.3 s reduction, P=.002). Medication errors were reduced from 70% to 0% (P<.001) by using PedAMINES when compared with conventional methods. In this simulation-based study, PedAMINES dramatically reduced TDP, to delivery and the rate of medication errors. ©Johan N Siebert, Frederic Ehrler, Christophe Combescure, Laurence Lacroix, Kevin Haddad, Oliver Sanchez, Alain Gervaix, Christian Lovis, Sergio Manzano. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 01.02.2017.

  14. Inverse problem to constrain the controlling parameters of large-scale heat transport processes: The Tiberias Basin example

    Science.gov (United States)

    Goretzki, Nora; Inbar, Nimrod; Siebert, Christian; Möller, Peter; Rosenthal, Eliyahu; Schneider, Michael; Magri, Fabien

    2015-04-01

    Element Modeling of Flow, Mass and Heat Transport in Porous and Fractured Media. Springer- Verlag Berlin Heidelberg ,996p. Doherty J., 2010, PEST: Model-Independent Parameter Estimation. user manual 5th Edition. Watermark, Brisbane, Australia Magri, F., Inbar, N., Siebert C., Rosenthal, E., Guttman, J., Möller, P., 2015. Transient simulations of large-scale hydrogeological processes causing temperature and salinity anomalies in the Tiberias Basin. Journal of Hydrology, 520(0), 342-355.

  15. Commercial Eldorado?

    Directory of Open Access Journals (Sweden)

    Rosemarijn Hoefte

    1996-07-01

    Full Text Available [First paragraph] De eerste Adam & De rots der struikeling. BOELI VAN LEEUWEN. Amsterdam: Ooievaar, 1996. 237 pp. (Paper NLG 25.00 Gedane zaken: De beste verhalen. HUGO Pos. Amsterdam: Ooievaar, 1996. 230 pp. (Paper NLG 15.00 Maar ik blijf. ASTRID H. ROEMER. Amsterdam: Ooievaar, 1996. 763 pp. (Paper NLG 25.00 De allermooiste romans van de Antillen en Suriname. Amsterdam: De Bezige Bij, 1996. 605 pp. (Paper NLG 39.90 Zingende eilanden. WIM RUTGERS (ed.. Amsterdam: De Bezige Bij, 1996. 317 pp. (Paper NLG 25.00 De eeuwige belofte van Eldorado: Verhalen over Latijns-Amerika en het Caribisch gebied. Nieuwegein: Aspekt, 1996. 188 pp. (Paper NLG 34.50 Echo van eldorado. ROSEMARIJN HOEFTE & GERT OOSTINDIE (comps. Leiden: KITLV Uitgeverij, 1996. 150 pp. (Paper NLG 15.00 Achter het eeuwig El Dorado: Fictie en realiteit in Latijnsamerikaanse literatuur. GEERT A. BANCK et al. Amsterdam: Thela, 1996. 140 pp. (Paper NLG 19.90 Eldorado: Werkelijkheid en droom. ROBERT LEMM. Amsterdam: Arbeiderspers, 1996. 160 pp. (Paper NLG 29.90 302 New West Indian Guide/Nieuwe West-Indische Gids vol. 70 rw. 3 & 4 Surinaamse recepten van A tot Z. MURIEL SAM-SIN-HEWITT. Schoorl: Conserve, 1996. 243 pp. (Paper NLG 29.95 De Bonistraat. AMBER NAHAR. Amsterdam: Piramide, 1996. 71 pp. (Cloth NLG 19.90 Beneden en boven de wind: Literatuur van de Nederlandse Antillen en Aruba. WIM RUTGERS. Amsterdam: De Bezige Bij, 1996. 468 pp. (Paper NLG 54.90 Elisabeth Samson: Een vrije, zwarte vrouw in het 18e-eeuwse Suriname. CYNTHIA MC LEOD. Schoorl: Conserve, 1996. 177 pp. (Paper NLG 29.90 De beroepsherinneraar en andere verhalen. ANIL RAMDAS. Amsterdam: De Bezige Bij, 1996. 280 pp. (Paper NLG 34.90 Geef mij maareen Surinamer. RONALD SNIJDERS. Amsterdam: Prometheus, 1996. 88 pp. (Paper NLG 19.90 De vrolijke dood van David Caprino. HENRY MENCKEBERG. Amsterdam: Meulenhoff. 291 pp. (Paper NLG 39.90 Caribische winter. ANNA BRIDIÉ. Amsterdam: Contact, 1996. 222 pp. (Cloth NLG 39

  16. Book Reviews

    Directory of Open Access Journals (Sweden)

    Nico G. Schulte Nordholt

    1996-01-01

    Full Text Available - Timothy P. Barnard, Raja Ali Haji, Di dalam berkekalan persahabatan: ‘In everlasting friendship’; Letters from Raja Ali Haji, edited by Jan van der Putten and Al Azhar. Semaian 13. Leiden: Department of Languages and Cultures of Southeast Asia and Oceania, 1995, 292 + x pp., maps. - Robert Blust, L. Smits, Irian Jaya source materials, no. 5, series B-no. 2. The J.C. Anceaux collection of wordlists of Irian Jaya Languages. A: Austronesian languages (part II. Leiden/Jakarta, 1992, 288 pp., C.L. Voorhoeve (eds. - Peter Boomgaard, Mason C. Hoadley, Towards a feudal mode of production; West Java, 1680-1800. Singapore: Institute of Southeast Asian Studies [ in cooperation with the Nordic Institute of Asian Studies, Copenhagen], 1994, x + 241 pp. - Freek Colombijn, Muriel Charras, Spontaneous settlements in Indonesia; Agricultural pioneers in southern Sumatra. Migrations spontanées en Indonésie; La colonisation agricole de sud de Sumatra. Jakarta: Departemen Transmigrasi; Paris: ORSTOM-CNRS, 1993, 405 pp., Marc Pain (eds. - Dick Douwes, Hussin Mutalib, Islam, Muslims and the modern state; Case-studies of Muslims in thirteen countries. London: MacMillan; New York: St. Martin Press, 1994, 374 pp., Taj ul-Islam Hashimi (eds. - J. van Goor, H.W. van den Doel, De stille macht; Het Europse binnenlands bestuur op Java en Madoera, 1808-1942. Amsterdam: Bert Bakker, 1994, 578 pp. - Stuart Kirsch, J.W. Schoorl, Culture and change among the Muyu. Translated by G.J. van Exel. Translation Series 23. Leiden: KITLV Press, 1993, xiv + 322 pp. - Bernd Nothofer, Ger P. Resink, Topics in descriptive Papuan linguistics. Leiden: Vakgroep Talen en Culturen van Zuidoost-Azië en Oceanië, Rijksuniversiteit te Leiden, 1994, viii + 154 pp. - Gerard Persoon, Robin Broad, Plundering paradise; The struggle for the environment in the Philippines. Berkeley: University of California Press, 1993, xvi + 197 pp., John Cavanagh (eds. - Gerard Persoon, Thomas N. Headland

  17. Annual Report 2001. Plataforma Solar de Almeria

    International Nuclear Information System (INIS)

    2002-01-01

    without a doubt in the immediate future a new challenge for the PSA and the team that comprises it, since it will have to confront new R and D requirements associated with industrial demand. This activity must be combined with better integration into the Spanish R and D system under the new policies being reinforced since the creation in 2000 of the Ministry of Science and Technology. I would not like to end this introduction without acknowledging the professionalism and dedication of the PSA team, without whom it could not function and achievement of the objectives set would be impossible. Special mention is due the previous director, Dr. Manuel Blanco Muriel, whose determination and fine work from 1999-2001 contributed in large part to the consolidated future of this great scientific facility. (Author)

  18. Agreement for depression diagnosis between DSM-IV-TR criteria, three validated scales, oncologist assessment, and psychiatric clinical interview in elderly patients with advanced ovarian cancer

    Directory of Open Access Journals (Sweden)

    Rhondali W

    2015-07-01

    Full Text Available Wadih Rhondali,1 Gilles Freyer,2 Virginie Adam,3 Marilène Filbet,4 Martine Derzelle,5 Gaelle Abgrall-Barbry,6 Sophie Bourcelot,7 Jean-Louis Machavoine,8 Muriel Chomat-Neyraud,9 Olivier Gisserot,10 Rémi Largillier,11 Annick Le Rol,12 Frank Priou,13 Pierre Saltel,14 Claire Falandry15 1Clinique Mon Repos, Clinea, Marseille, France; 2Medical Oncology Unit, Centre Hospitalier Lyon Sud, Université Lyon 1, Pierre-Benite, France; 3Institut de Cancérologie de Lorraine Alexis Vautrin, Vandoeuvre-lès-Nancy, France; 4Palliative Unit, Centre Hospitalier Lyon Sud, Université Lyon 1, Pierre-Benite, France; 5Institut Jean Godinot, Reims, France; 6Tenon Hospital, Assistance Publique Hôpitaux de Paris, Paris, France; 7Centre Léon Bérard, Lyon, France; 8Centre François Baclesse, Caen, France; 9Centre Hospitalier de la région d’Annecy, Pringy, France; 10Hôpital d’Instruction des Armées Sainte-Anne, Toulon, France; 11Centre Azuréen de Cancérologie, Mougins, France; 12Medical Oncology, Hôpital Perpétuel Secours, Levallois-Perret, France; 13Medical Oncology, Centre Hospitalier Départemental Les Oudairies, La Roche-sur-Yon, France; 14Supportive Care Department, Centre Léon Bérard, Lyon, France; 15Geriatrics and Oncology Unit, Centre Hospitalier Lyon Sud, Université Lyon 1, Pierre-Bénite, France Background: Depression, a major outcome in cancer patients, is often evaluated by physicians relying on their clinical impressions rather than patient self-report. Our aim was to assess agreement between patient self-reported depression, oncologist assessment (OA, and psychiatric clinical interview (PCI in elderly patients with advanced ovarian cancer (AOC.Methods: This analysis was a secondary endpoint of the Elderly Women AOC Trial 3 (EWOT3, designed to assess the impact of geriatric covariates, notably depression, on survival in patients older than 70 years of age. Depression was assessed using the Geriatric Depression Scale-30 (GDS, the Hospital

  19. Anti-inflammatory and immunomodulatory effects of Aquaphilus dolomiae extract on in vitro models

    Directory of Open Access Journals (Sweden)

    Aries MF

    2016-11-01

    Full Text Available Marie-Françoise Aries,1 Hélène Hernandez-Pigeon,1 Clémence Vaissière,1 Hélène Delga,1 Antony Caruana,1 Marguerite Lévêque,1 Muriel Bourrain,1,2 Katia Ravard Helffer,1 Bertrand Chol,3 Thien Nguyen,1 Sandrine Bessou-Touya,1 Nathalie Castex-Rizzi1 1Pierre Fabre Dermo-Cosmétique, Centre de Recherche & Développement Pierre Fabre, Toulouse, 2Sorbonne Universités, UPMC Univ Paris 06, CNRS, Laboratoire de Biodiversité et Biotechnologies Microbiennes (LBBM, Observatoire Océanologique, Banyuls/Mer, France; 3Centre d’Immunologie Pierre Fabre, Saint-Julien-en-Genevois, France Background: Atopic dermatitis (AD is a common skin disease characterized by recurrent pruritic inflammatory skin lesions resulting from structural and immune defects of the skin barrier. Previous studies have shown the clinical efficacy of Avène thermal spring water in AD, and a new microorganism, Aquaphilus dolomiae was suspected to contribute to these unique properties. The present study evaluated the anti-inflammatory, antipruritic, and immunomodulatory properties of ES0, an original biological extract of A. dolomiae, in immune and inflammatory cell models in order to assess its potential use in the treatment of AD.Materials and methods: An ES0 extract containing periplasmic and membrane proteins, peptides, lipopolysaccharides, and exopolysaccharides was obtained from A. dolomiae. The effects of the extract on pruritus and inflammatory mediators and immune mechanisms were evaluated by using various AD cell models and assays.Results: In a keratinocyte model, ES0 inhibited the expression of the inflammatory mediators, thymic stromal lymphopoietin, interleukin (IL-18, IL-4R, IL-8, monocyte chemoattractant protein-3, macrophage inflammatory protein-3α, and macrophage-derived chemokine and induced the expression of involucrin, which is involved in skin barrier keratinocyte terminal differentiation. In addition, ES0 inhibited protease-activated receptor-2 activation in

  20. Acceptance of a reusable self-injection device for recombinant human growth hormone: final data from a questionnaire-based, cross-sectional, international, multicenter, observational study in pediatric patients

    Directory of Open Access Journals (Sweden)

    Schnabel D

    2016-09-01

    Full Text Available Dirk Schnabel,1 Carl-Joachim Partsch,2 Muriel Houang,3 Sarah Ehtisham,4 Helen Johnstone,5 Markus Zabransky,6 Wieland Kiess7 1Pediatric Endocrinology, Center for Chronic Sick Children, Otto-Heubner-Centrum für Kinder- und Jugendmedizin, Charite, University Medicine, Berlin, Germany; 2Endokrinologikum Hamburg, Hamburg, Germany; 3Explorations Fonctionnelles Endocriniennes, Hôpital Armand Trousseau, Paris, France; 4Mediclinic City Hospital, Dubai Healthcare City, Dubai, United Arab Emirates; 5The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, UK; 6Sandoz International GmbH, Holzkirchen, 7Department of Women and Child Health, Hospital for Children and Adolescents, University Hospitals, University of Leipzig, Leipzig, Germany Background: A questionnaire-based survey was conducted to assess attitudes toward a reusable self-injection system (SurePal™ among pediatric patients with growth disturbances who were prescribed treatment with Omnitrope® within routine clinical practice.Methods: This was a multicenter, observational study, incorporated into the noninterventional PAtients TReated with Omnitrope® (PATRO Children study. Included subjects, or their caregivers, completed a questionnaire on the following five main areas: attractiveness of SurePal™, training received, using the device, the low drug wastage system, and experience versus other devices used previously (pretreated patients. Responses were based on a 5-point scale, with 2 being the best possible outcome and −2 the worst possible outcome.Results: In total, 550 patients were included in this study (338 from France, 169 from Germany, and 43 from the UK. The mean age ± standard deviation of participants was 10.8±3.5 years; the majority (57% were male and growth hormone treatment naïve (88%. Almost half (49.8% of children prepared their SurePal™ for injection themselves and 45.5% performed injections themselves. As patients progressed into their teens, the majority

  1. Large-scale thermal convection of viscous fluids in a faulted system: 3D test case for numerical codes

    Science.gov (United States)

    Magri, Fabien; Cacace, Mauro; Fischer, Thomas; Kolditz, Olaf; Wang, Wenqing; Watanabe, Norihiro

    2017-04-01

    Earth Sciences, 67(2), 589-599. Diersch, H. J, 2014. FEFLOW Finite Element Modeling of Flow, Mass and Heat Transport in Porous and Fractured Media, Springer-Verlag Berlin Heidelberg, ISBN 978-3-642-38738-8. Gaston D., Newman C., Hansen G., Lebrun-Grandie D, 2009. MOOSE: A parallel solution framework for coupled systems of nonlinear equations. Nucl. Engrg. Design, 239, 1,768-1778 Magri, F., Möller, S., Inbar, N., Möller, P., Raggad, M., Rödiger, T., Rosenthal, E., Siebert, C., 2016. 2D and 3D coexisting modes of thermal convection in fractured hydrothermal systems - Implications for transboundary flow in the Lower Yarmouk Gorge. Marine and Petroleum Geology 78, 750-758, DOI: /10.1016/j.marpetgeo.2016.10.002 Malkovsky, V. I., Magri, F., 2016. Thermal convection of temperature-dependent viscous fluids within three-dimensional faulted geothermal systems: estimation from linear and numerical analyses, Water Resour. Res., 52, 2855-2867, DOI:10.1002/2015WR018001.

  2. Indirect treatment comparison of bevacizumab + interferon-α-2a vs tyrosine kinase inhibitors in first-line metastatic renal cell carcinoma therapy

    Directory of Open Access Journals (Sweden)

    Gerald HJ Mickisch

    2011-01-01

    Full Text Available Gerald HJ Mickisch1, Björn Schwander2, Bernard Escudier3, Joaquim Bellmunt4, José P Maroto5, Camillo Porta6, Stefan Walzer7, Uwe Siebert8,91Department of Urology, Center of Operative Urology Bremen, Bremen, Germany; 2Department of Outcomes Research, AiM GmbH Assessment-in-Medicine, Lörrach, Germany; 3Immunotherapy Unit, Institut Gustave Roussy, Villejuif, France; 4Department of Medical Oncology, University Hospital del Mar UPF, Barcelona, Spain; 5Department of Medical Oncology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain; 6Department of Medical Oncology, IRCCS San Matteo University Hospital Foundation, Pavia, Italy; 7Global Health Economics, F Hoffmann-La Roche Pharmaceuticals AG, Basel, Switzerland; 8Department of Public Health, Medical Decision Making and Health Technology Assessment, UMIT - University for Health Sciences, Medical Informatics and Technology, Hall i.T., Austria; 9Department of Health Policy and Management, Harvard School of Public Health, Boston, MA, USABackground: The vascular endothelial growth factor inhibitor bevacizumab (BEV given in combination with interferon-α-2a (IFN, and the tyrosine kinase inhibitors (TKIs sunitinib (SUN and pazopanib (PAZ, have all shown significant increase in progression-free survival (PFS in first-line metastatic renal-cell carcinoma (mRCC therapy. These targeted therapies are currently competing to be primary choice; hence, in the absence of direct head-to-head comparison, there is a need for valid indirect comparison assessment.Methods: Standard indirect comparison methods were applied to independent review PFS data of the pivotal Phase III trials, to determine indirect treatment comparison hazard-ratios (HR with 95% confidence intervals (95% CI. As BEV+IFN and SUN have been compared to IFN, indirect comparison was enabled by the common IFN comparator arms. As PAZ was compared to placebo (PLA, a connector trial (IFN vs PLA was required for the indirect comparison to BEV

  3. New structural/tectonical model and its implication on hydrological thinking and groundwater management - the Lake Tiberias, Jordan Rift Valley

    Science.gov (United States)

    Inbar, Nimrod; Magri, Fabien; Yellin-Dror, Annat; Rosenthal, Eliahu; Möller, Peter; Siebert, Christian; Guttman, Josef

    2014-05-01

    juxtaposing salt rock to the hydrological system was overlooked. Recent study reported an anomaly in groundwater chemistry at the western shore, indicating a possible contribution of halite dissolution into the ascending brine (Möller et al., 2011). This correlates to the results of the salt tectonic model and the suspected salt diapir above mentioned. Moreover, Arbel-1 borehole (drilled at 2003 at the same area) showed rapid salinity increase during pumping. Today the well is shut off. Based on the above findings, a numerical model is built. The studied profile crosses the rift from the Galilee at the west to the Golan and Ajlun at the east reaching a depth of 6 kilometers. The model indicates the possible brine flow paths across the rift and their interaction with fresh water aquifers and lake springs. References Inbar, N. (2012), The Evaporatic Subsurface Body in Kinnarot Basin: Stratigraphy, Structure, Geohydrology, 131 pp, Tel Aviv University. Möller, P., Siebert, C., Geyer, S., Inbar, N., Rosenthal, E., Flexer, A., and Zilberbrand, M. (2011), Relationships of Brines in the Kinnarot Basin, Jordan-Dead Sea Rift Valley, Geofluids (doi: 10.1111/j.1468-8123.2011.00353.x). Reznikov, M., Ben-Avraham, Z., Garfunkel, Z., Gvirtzman, H. and Rotstein, Y., 2004. Structural and stratigraphic framework of Lake Kinneret: Isr. J. Earth Sci., v. 53, p. 131-149.

  4. 3D hydrogeological model of the Lower Yarmouk Gorge, Jordan Rift Valley

    Science.gov (United States)

    Magri, Fabien; Inbar, Nimrod; Möller, Peter; Raggad, Marwan; Rödiger, Tino; Rosenthal, Eliahu; Shentsis, Izabela; Tzoufka, Kalliopi; Siebert, Christian

    2017-04-01

    the location of discharge areas while the anomalous spring temperature is not necessarily linked to the presence of fault convection. Local permeability anisotropy due to aquifers folding or facies changes are features sufficient for the rising of hot fluids. References Shentsis (1990). Mathematical models for long-term prediction of mountainous river runoff: methods, information and results, Hydrological Sciences Journal, 35:5, 487-500, DOI: 10.1080/02626669009492453 Magri, F., Möller, S., Inbar, N., Möller, P., Raggad, M., Rödiger, T., Rosenthal, E., Siebert, C., 2016. 2D and 3D coexisting modes of thermal convection in fractured hydrothermal systems - Implications for transboundary flow in the Lower Yarmouk Gorge. Marine and Petroleum Geology 78, 750-75, DOI: /10.1016/j.marpetgeo.2016.10.002

  5. Modeling spatially- and temporally-explicit water stress indices for use in life cycle assessment

    Science.gov (United States)

    Scherer, L.; Venkatesh, A.; Karuppiah, R.; Usadi, A.; Pfister, S.; Hellweg, S.

    2013-12-01

    model regions (including Africa and North America). These WSIs were used to estimate revised CFs for freshwater consumption to be used in LCAs. Future work will extend results to a global scale. References 1. Brown, A., Matlock, M., 2011. A Review of Water Scarcity Indices and Methodologies, University of Kansas, The Sustainability Consortium, White Paper #106. 2. Pfister, S., Koehler, A., Hellweg, S., 2009. Assessing the Environmental Impacts of Freshwater Consumption in LCA. Environ. Sci. Technol. 43 (11), 4098-4104. 3. Alcamo, J.; Doll, P.; Henrichs, T.; Kaspar, F.; Lehner, B.; Rosch, T.; Siebert, S. Development and testing of the WaterGAP 2 global model of water use and availability Hydrol. Sci. J. 2003, 48 (3) 317- 337. 4. Arnold, J.G., Srinivasan, R., Muttiah, R.S., Allen, P.M., 1999. Continental scale simulation of the hydrologic balance. J. Am.Water Resour. Assoc. 35 (5), 1037-1051. 5. Pfister, S., Bayer, P., Koehler, A., Hellweg, S., 2011. Environmental Impacts of Water Use in Global Crop Production: Hotspots and Trade-Offs with Land Use. Environ. Sci. Technol. 45 (13), 5761- 5768.

  6. A Mobile Device App to Reduce Medication Errors and Time to Drug Delivery During Pediatric Cardiopulmonary Resuscitation: Study Protocol of a Multicenter Randomized Controlled Crossover Trial.

    Science.gov (United States)

    Siebert, Johan N; Ehrler, Frederic; Lovis, Christian; Combescure, Christophe; Haddad, Kevin; Gervaix, Alain; Manzano, Sergio

    2017-08-22

    prescription by the physician to drug delivery by the nurse in each allocation group. TDD includes TDP. Stress level during the resuscitation scenario will be assessed for each participant by questionnaire and recorded by the heart rate monitor of a fitness watch. The study is formatted according to the Consolidated Standards of Reporting Trials Statement for Randomized Controlled Trials of Electronic and Mobile Health Applications and Online TeleHealth (CONSORT-EHEALTH) and the Reporting Guidelines for Health Care Simulation Research. Enrollment and data analysis started in March 2017. We anticipate the intervention will be completed in late 2017, and study results will be submitted in early 2018 for publication expected in mid-2018. Results will be reported in line with recommendations from CONSORT-EHEALTH and the Reporting Guidelines for Health Care Simulation Research . This paper describes the protocol used for a clinical trial assessing the impact of a mobile device app to reduce the rate of medication errors, time to drug preparation, and time to drug delivery during pediatric resuscitation. As research in this area is scarce, results generated from this study will be of great importance and might be sufficient to change and improve the pediatric emergency care practice. ClinicalTrials.gov NCT03021122; https://clinicaltrials.gov/ct2/show/NCT03021122 (Archived by WebCite at http://www.webcitation.org/6nfVJ5b4R). ©Johan N Siebert, Frederic Ehrler, Christian Lovis, Christophe Combescure, Kevin Haddad, Alain Gervaix, Sergio Manzano. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 22.08.2017.

  7. Trends and Issues in Distance Education: International Perspectives

    Directory of Open Access Journals (Sweden)

    Erhan EROGLU

    2006-04-01

    . Muriel VISSER - VALFREY, Jan VISSER, and Miguel BUENDIA PART IV DESIGN AND DEVELOPMENT TRENDS FOR INTERNATIONAL DISTANCE EDUCATION Learning Management Systems (LMS for Web-based Distance Education: An International Review. Wei-yuan ZHANG and Lixun WANG Trends in Distance Education Technologies from an International Vantage Point. Michael SIMONSON Dynamism and Evolution in Student Support and Instruction in Distance Education: Implications for International Distance Education. Yusra Laila VISSER About the Authors

  8. Global Cropland Area Database (GCAD) derived from Remote Sensing in Support of Food Security in the Twenty-first Century: Current Achievements and Future Possibilities

    Science.gov (United States)

    Teluguntla, Pardhasaradhi G.; Thenkabail, Prasad S.; Xiong, Jun N.; Gumma, Murali Krishna; Giri, Chandra; Milesi, Cristina; Ozdogan, Mutlu; Congalton, Russ; Tilton, James; Sankey, Temuulen Tsagaan; Massey, Richard; Phalke, Aparna; Yadav, Kamini

    2015-01-01

    The precise estimation of the global agricultural cropland- extents, areas, geographic locations, crop types, cropping intensities, and their watering methods (irrigated or rainfed; type of irrigation) provides a critical scientific basis for the development of water and food security policies (Thenkabail et al., 2012, 2011, 2010). By year 2100, the global human population is expected to grow to 10.4 billion under median fertility variants or higher under constant or higher fertility variants (Table 1) with over three quarters living in developing countries, in regions that already lack the capacity to produce enough food. With current agricultural practices, the increased demand for food and nutrition would require in about 2 billion hectares of additional cropland, about twice the equivalent to the land area of the United States, and lead to significant increases in greenhouse gas productions (Tillman et al., 2011). For example, during 1960-2010 world population more than doubled from 3 billion to 7 billion. The nutritional demand of the population also grew swiftly during this period from an average of about 2000 calories per day per person in 1960 to nearly 3000 calories per day per person in 2010. The food demand of increased population along with increased nutritional demand during this period (1960-2010) was met by the “green revolution” which more than tripled the food production; even though croplands decreased from about 0.43 ha/capita to 0.26 ha/capita (FAO, 2009). The increase in food production during the green revolution was the result of factors such as: (a) expansion in irrigated areas which increased from 130 Mha in 1960s to 278.4 Mha in year 2000 (Siebert et al., 2006) or 399 Mha when you do not consider cropping intensity (Thenkabail et al., 2009a, 2009b, 2009c) or 467 Mha when you consider cropping intensity (Thenkabail et al., 2009a; Thenkabail et al., 2009c); (b) increase in yield and per capita food production (e.g., cereal production

  9. The First 24 Years of Reverse Monte Carlo Modelling, Budapest, Hungary, 20-22 September 2012

    Science.gov (United States)

    Keen, David A.; Pusztai, László

    2013-11-01

    structure of the plastic crystalline and liquid phases of CBr2Cl2: neutron diffraction and reverse Monte Carlo modellingSzilvia Pothoczki1, László Temleitner, Luis Carlos Pardo, Gabriel Julio Cuello, Muriel Rovira-Esteva and Josep Lluis Tamarit Insights into the determination of molecular structure from diffraction data using a Bayesian algorithmA Henao, M Rovira-Esteva, A Vispa, J Ll Tamarit, E Guardia and L C Pardo Nanostructure determination from the pair distribution function: a parametric study of the INVERT approachMatthew J Cliffe and Andrew L Goodwin Empirical potential structure refinement of semi-crystalline polymer systems: polytetrafluoroethylene and polychlorotrifluoroethyleneA K Soper, K Page and A Llobet spinvert: a program for refinement of paramagnetic diffuse scattering dataJoseph A M Paddison, J Ross Stewart and Andrew L Goodwin Inter-molecular correlations in liquid Se2Br2Hironori Shimakura, Yukinobu Kawakita, Koji Ohara, László Pusztai, Yuiko Wakisaka and Shin'ichi Takeda RMCgui: a new interface for the workflow associated with running Reverse Monte Carlo simulationsMartin T Dove and Gary Rigg

  10. PREFACE Integrability and nonlinear phenomena Integrability and nonlinear phenomena

    Science.gov (United States)

    Gómez-Ullate, David; Lombardo, Sara; Mañas, Manuel; Mazzocco, Marta; Nijhoff, Frank; Sommacal, Matteo

    2010-10-01

    derivative nonlinear Schroedinger (DNLS) equation. Ragnisco and Zullo [18] construct Backlund transformations for the trigonometric classical Gaudin magnet in the partially anisotropic (xxz) case, identifying the subcase of transformations that preserve the real character of the variables. The recently discovered exceptional polynomials are complete polynomial systems that satisfy Sturm-Liouville problems but differ from the classical families of Hermite, Laguerre and Jacobi. Gomez-Ullate et al [19] prove that the families of exceptional orthogonal polynomials known to date can be obtained from the classical ones via a Darboux transformation, which becomes a useful tool to derive some of their properties. Integrability in the context of classical mechanics is associated to the existence of a sufficient number of conserved quantities, which allows sometimes an explicit integration of the equations of motion. This is the case for the motion of the Chaplygin sleigh, a rigid body motion on a fluid with nonholonomic constraints studied in the paper by Fedorov and Garcia-Naranjo [20], who derive explicit solutions and study their asymptotic behaviour. In connection with classical mechanics, some techniques of KAM theory have been used by Procesi [21] to derive normal forms for the NLS equation in its Hamiltonian formulation and prove existence and stability of quasi-periodic solutions in the case of periodic boundary conditions. Algebraic and group theoretic aspects of integrability are covered in a number of papers in the issue. The quest for symmetries of a system of differential equations usually allows us to reduce the order or the number of equations or to find special solutions possesing that symmetry, but algebraic aspects of integrable systems encompass a wide and rich spectrum of techniques, as evidenced by the following contributions. Muriel and Romero [22] perform a systematic study of all second order nonlinear ODEs that are linearizable by generalized Sundman and