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Sample records for paris vii internationalizing

  1. Chemical characteristics of saponins from Paris fargesii var. brevipetala and cytotoxic activity of its main ingredient, paris saponin H.

    Science.gov (United States)

    Wen, Feiyan; Yin, Hongxiang; Chen, Chu; Liu, Xianbo; Xue, Dan; Chen, Tiezhu; He, Jun; Zhang, Hao

    2012-06-01

    More attention was paid to the anti-tumor activity of Rhizoma Paridis (RP) recently, of which the wild resource was decreased significantly. This study was aimed to elucidate the chemical characteristics of Paris fargesii var. brevipetala (PFB) that may be administrated as alternate resource of legal RP. A HPLC-ELSD method was established to characterize the steroid saponins in rhizomes of PFB and two legal Paris species [Paris polyphylla var. chinensis (PPC) and P. polyphylla var. yunnanensis (PPY)] in Chinese Pharmacopoeia (CP). Ten saponins (paris saponins I, II, V, VI, VII, H, gracillin and other three paris saponins) were involved as standards. The results indicated that PFB contained pennogenyl saponins as the main components with small amounts of diosgenin saponins. The total contents of the detected saponins in PFB ranged from 9.12mg/g to 85.33mg/g. Nine of the twelve PFB samples own a total content of paris saponins I, II, VI, and VII more than 6.0mg/g (meeting the standard of CP 2010 edition). Principal Component Analysis (PCA) and Partial Least Squares-Discriminate Analysis (PLS-DA) both confirmed the fact that saponin profiles of PFB, PPC and PPY were different from each other. In addition, paris saponin H (Ps H), the predominant saponin of PFB (>50%), was tested in vitro to evaluate its cytotoxic activities on HepG2, A549, RPE and L929 cells with a positive control of Cisplatin. Ps H showed a remarkable cytotoxic activity on A549 cells with an IC(50) value of 1.53±0.08μg/mL. Copyright © 2012 Elsevier B.V. All rights reserved.

  2. Mary McAuliffe. Twilight of the Belle Epoque: The Paris of Picasso, Stravinsky, Proust, Renault, Marie Curie, Gertrude Stein, and Their Friends through the Great War. Lanham, MD: Rowman and Littlefield. 2014. vii + 418 pp.

    Directory of Open Access Journals (Sweden)

    Eric Martone

    2015-01-01

    Full Text Available Review of Mary McAuliffe. Twilight of the Belle Epoque: The Paris of Picasso, Stravinsky, Proust, Renault, Marie Curie, Gertrude Stein, and Their Friends through the Great War . Lanham, MD: Rowman and Littlefield. 2014. vii + 418 pp.

  3. De-internationalization

    DEFF Research Database (Denmark)

    Turcan, Romeo V.

    In this paper I discuss the evolution of the concept of de-internationalization. I look at the evolution of de-internationalization via empirical and theoretical lenses. I draw on recent empirical evidence to exemplify the evolution of what, how, why, who, where, when of de-internationalization. I...... then discuss the evolution of theoretical developments of the concept employing a number theory building strategies. I conclude the paper by mapping theoretical landscape of de-internationalization phenomenon suggesting future research directions....

  4. To Internationalize or Not to Internationalize? A Descriptive Study of a Brazilian Startup

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    Flavia Luciane Scherer

    2018-03-01

    Full Text Available This study examines the failed internationalization experience of a Brazilian high-tech startup. The research methodology of the study is descriptive and aims to explore whether this startup should re-internationalize, despite an unsuccessful first experience. Based on interviews with the founders, it was found that the initial internationalization took place in an incipient way, in the heat of the moment. The lack of success with the initial internationalization did not shake the directors of the startup, who aim to return to internationalization, now in a consolidated way and counting on the advice of an investor. Despite its bitter first experience, should the startup try again? Through an analysis of the lessons learned from the startup’s initial failure and insights from its consideration of a possible second attempt, this study contributes to the literature on competitiveness, internationalization, and international entrepreneurship.

  5. The lure of internationalization

    DEFF Research Database (Denmark)

    Fabricius, Anne; Mortensen, Janus; Haberland, Hartmut

    2017-01-01

    with a general characterization of the discourse of mobility and internationalization in a European context, and then turn to Denmark as a specific case in which we unfold and discuss three paradoxes in turn: internationalization and linguistic pluralism, internationalization and intercultural understanding, and......, finally, internationalization and competitiveness. We then link our deconstruction of the three paradoxes to a critique of the concept of ‘parallel language policy’, widely promoted in the Nordic context, and show how it in effect undermines the ideals of internationalisation....

  6. Internationalization or globalization of higher education.

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    Rezaei, Habibolah; Yousefi, Alireza; Larijani, Bagher; Dehnavieh, Reza; Rezaei, Nima; Adibi, Peyman

    2018-01-01

    Studies about globalization and internationalization demonstrate different attitudes in explaining these concepts. Since there is no consensus among Iranian specialists about these concepts, the purpose of this study is to explain the concepts of internationalization and globalization in Iran. This study is a systematic review done in the first half of 2016. To explain the concept of globalization and internationalization, articles in Scientific Information D atabase, Magiran database, and Google Scholar were searched with the keywords such as globalization, scientific exchange, international cooperation, curriculum exchange, student exchange, faculty exchange, multinational cooperation, transnational cooperation, and collaborative research. Articles, used in this study, were in Persian and were devoted to internationalization and globalization between 2001 and 2016. The criterion of discarding the articles was duplicity. As many as 180 Persian articles were found on this topic. After discarding repetitive articles, 64 remained. Among those, 39 articles mentioned the differences between globalization and internationalization. Definitions of globalization were categorized in four categories, including globalization, globalizing, globalization of higher education, and globalizing of higher education. Definitions about internationalization were categorized in five categories such as internationalization, internationalization of higher education, internationalization of the curriculum, internationalization of curriculum studies, and internationalization of curriculum profession. The spectrum of the globalization of higher education moves from dissonance and multipolarization to unification and single polarization of the world. One end of the spectrum, which is unification and single polarization of the world, is interpreted as globalization. The other side of the spectrum, which is dissonance and multipolarization, is interpreted as globalizing. The definition of

  7. Internationalization or globalization of higher education

    Science.gov (United States)

    Rezaei, Habibolah; Yousefi, Alireza; Larijani, Bagher; Dehnavieh, Reza; Rezaei, Nima; Adibi, Peyman

    2018-01-01

    INTRODUCTION: Studies about globalization and internationalization demonstrate different attitudes in explaining these concepts. Since there is no consensus among Iranian specialists about these concepts, the purpose of this study is to explain the concepts of internationalization and globalization in Iran. MATERIALS AND METHODS: This study is a systematic review done in the first half of 2016. To explain the concept of globalization and internationalization, articles in Scientific Information D atabase, Magiran database, and Google Scholar were searched with the keywords such as globalization, scientific exchange, international cooperation, curriculum exchange, student exchange, faculty exchange, multinational cooperation, transnational cooperation, and collaborative research. Articles, used in this study, were in Persian and were devoted to internationalization and globalization between 2001 and 2016. The criterion of discarding the articles was duplicity. RESULTS: As many as 180 Persian articles were found on this topic. After discarding repetitive articles, 64 remained. Among those, 39 articles mentioned the differences between globalization and internationalization. Definitions of globalization were categorized in four categories, including globalization, globalizing, globalization of higher education, and globalizing of higher education. Definitions about internationalization were categorized in five categories such as internationalization, internationalization of higher education, internationalization of the curriculum, internationalization of curriculum studies, and internationalization of curriculum profession. CONCLUSION: The spectrum of the globalization of higher education moves from dissonance and multipolarization to unification and single polarization of the world. One end of the spectrum, which is unification and single polarization of the world, is interpreted as globalization. The other side of the spectrum, which is dissonance and

  8. Crowdsourced Translation for Rapid Internationalization in Cyberspace

    DEFF Research Database (Denmark)

    Tran, Yen; Yonatany, Moshe; Mahnke, Volker

    2016-01-01

    This paper explores how Facebook effectively used crowdsourced translation to accelerate its rapid internationalization. We apply the learning perspective of internationalization theory to unpack what the firm learned in order to mobilize crowd-based knowledge to facilitate internationalization...... and codified knowledge, rather than the experiential knowledge traditionally suggested in the literature on the process of internationalization, and (2) the firm's success rested on its ability to use virtual learning tools and incentive systems to acquire, articulate and integrate knowledge from communities...... of internationally dispersed users – the “crowd” – to accelerate its internationalization in cyberspace. This empirical study extends internationalization theory regarding knowledge and organizational learning....

  9. Internationalization and the Dutch fashion industry : an investigation of inward and outward internationalization

    NARCIS (Netherlands)

    Divito, Lori; van Winden, Willem

    2014-01-01

    The overall topic of this book is internationalization. It is hard to deny that organizations are increasingly internationalizing in order to remain competitive, to access growth markets and resources and to reduce operating costs. Understanding international business has become imperative for

  10. Business Groups, Internationalization and Institutional Change

    DEFF Research Database (Denmark)

    Kumar, Vikas; Stucchi, Tamara; Kundu, Sumit K.

    2012-01-01

    Business group affiliation is an important determinant of firm economic performance in the context of emerging economies. However, relationship between business group affiliation and internationalization of firms remains unclear. In the context of internationalizing emerging economy firms, many...... of which are affiliates of larger business groups, the question of whether such an affiliation serves as a boon or bane in firm internationalization is one of critical importance. We argue that institutional changes play an important role in shaping the relationship between business group affiliation...... and the degree of internationalization. Our results, based on empirical analysis of Indian firm data, indicate a negative relationship between business group affiliation and the degree of internationalization during the initial period of major institutional change. In the latter period with greater institutional...

  11. De-Internationalization of Universities

    DEFF Research Database (Denmark)

    Turcan, Romeo V.; Gulieva, Valeria

    2016-01-01

    -internationalization as a theoretical lens and reviewed and analyzed available unobtrusive data such as running records as well as episodic and private records. A number of de-internationalization factors emerged: low student enrolment, wrong assumptions, bandwagon effect, staff immobility, lack of adaptability, brand identity...

  12. De-internationalization: A conceptualization

    DEFF Research Database (Denmark)

    Turcan, Romeo V.

    This paper aims to encourage a dynamic scholarly conversation about de-internationalization with the aim to further the progress of IB research, making a number of contributions. The paper delineates the domain of scholarly research on de-internationalization by developing a typology of de...

  13. INTERNATIONALIZATION IN HIGHER EDUCATION

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    Catalina Crisan-Mitra

    2016-03-01

    Full Text Available Internationalization of higher education is one of the key trends of development. There are several approaches on how to achieve competitiveness and performance in higher education and international academic mobility; students’ exchange programs, partnerships are some of the aspects that can play a significant role in this process. This paper wants to point out the student’s perception regarding two main directions: one about the master students’ expectation regarding how an internationalized master should be organized and should function, and second the degree of satisfaction of the beneficiaries of internationalized master programs from Babe-Bolyai University. This article is based on an empirical qualitative research that was implemented to students of an internationalized master from the Faculty of Economics and Business Administration. This research can be considered a useful example for those preoccupied to increase the quality of higher education and conclusions drawn have relevance both theoretically and especially practically.

  14. On the Internationalization of Chinese Accounting Standards

    Institute of Scientific and Technical Information of China (English)

    JU Ling Jiao

    2015-01-01

    Accounting internationalization has become an inexorable trend of world economic development. This paper begins with the analysis of the situation and trend of accounting internationalization in China. Then, based on the diferences between Chinese and international accounting standards (IAS), it ilustrates the inevitability of accounting internationalization in China. Finaly, the research provides suggestions for problems existing in the process of accounting internationalization in the country.

  15. On the Internationalization of Corporate Boards

    DEFF Research Database (Denmark)

    Oxelheim, Lars; Gregoric, Aleksandra; Randøy, Ttrond

    Despite the global reach of their commercial activities, many multinational firms have proved slow in internationalizing their boards of directors. Based on a panel study of the internationalization of the boards of 347 non-financial firms from the Nordic countries, we find a higher fraction...... of international board membership in firms with more foreign sales, in firms with more foreign ownership and in firms whose shares are traded on foreign (mostly European) stock exchanges. Moreover, we find international directors and national directors with international experience complementary. The first......-mentioned group is found to serve a monitoring role, related to financial internationalization of the firm, whereas the latter category fills an advisory role related to commercial internationalization. Hence, different types of firm internationalization – commercial versus financial – might call for different...

  16. Assessing a Historically Hispanic Serving Institution Internationalization Process

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    Flavia Iuspa

    2014-09-01

    Full Text Available This article presents a qualitative study conducted at a Historically Hispanic Serving Institution (HHSI to further the understanding of its internationalization decision-making process. The study uses the Internationalization Cube model to review the institution’s internal processes and policies toward internationalization and assess how its international activities align with its internationalization efforts. The Internationalization Cube, an eight-cell model, permits the positioning of Institutions of Higher Education (IHEs based on the analysis of its three dimensions and respective subcategories: policy, support, and implementation. The International Dimension Index (IDI and the Item Relevancy Index (IRI were also used to determine the level of alignment between the HHSI position on the Internationalization Cube and its international activities. The study finds that the HHSI is on Position 6 on the Internationalization Cube (priority policy, one-sided support, and systematic/structure implementation, and exhibits all the international activities considered indicators of internationalization but attention is needed to foreign language, international students, study abroad, faculty movement and involvement in international projects. The study concludes that an association exists between the institution’s position on the Internationalization Cube and its international activities, and adjustments in the institution’s policy, support, and implementation dimensions will be required to advance its position on the Internationalization Cube making its internationalization process more sustainable. This study makes a contribution to addressing the need to assess an IHE by presenting a holistic organizational framework instead of a fragmented international activities organizational analysis.

  17. The 'Casino Model' of Internationalization

    DEFF Research Database (Denmark)

    Håkanson, Lars; Kappen, Philip

    2017-01-01

    Forty years after the publication of the original Uppsala Model, we revisit the empirical observations that inspired its conceptual development. The empirical evidence, we suggest, invites the formulation of an alternative and complementary model of the internationalization process of the firm, o...... that we have named the 'Casino Model' of internationalization. The Casino Model uncovers a number of new research issues pertaining to internationalization and to the nature of strategic decision-making under conditions of environmental uncertainty and partial ignorance....

  18. Exploring the relationship between university internationalization and university autonomy

    DEFF Research Database (Denmark)

    Turcan, Romeo V.; Gullieva, Valeria

    This paper explores a research gap at the intersection of university internationalization and university autonomy. A process model of university internationalization is put forward whereby the process of university internationalization is mediated by university internationalization capacity...... and moderated by target country institutional autonomy and globalization; and entry modes, timing and pace, as well as product mix of internationalization define university’s internationalization pattern. A systematic review is conducted to identify empirical studies at this intersection. One of the questions...

  19. Planning for Internationalization By Investing in Faculty

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    Lisa K. Childress

    2009-11-01

    Full Text Available Over the last half century, major world events have prompted higher education institutions to develop internationalization plans. In order engage faculty in internationalization, higher education scholars and practitioners have recommended that internationalization plans include allocated resources, such as budgets for academic exchanges, faculty development workshops, and international curricular development and research grants (Olson, Green, & Hill, 2006; Paige, 2005; Siaya & Hayward, 2003. Yet, a frequently cited obstacle to faculty engagement in internationalization plans is lack of funding (Backman, 1984; Bond, 2003; Ellingboe, 1998; Green & Olson, 2003; Steers & Ungsen, 1992; Woolston, 1983. A cross-case analysis reveals that differential investment leads to faculty engagement in internationalization plans. This article discusses how two institutions developed funds from a variety of sources and institutional levels to engage faculty in an institutional planning process. This study offers implications for institutional planning, resource dependency theory, and internationalization.

  20. Internationalization Revisited

    DEFF Research Database (Denmark)

    Pedersen, Torben; Shaver, Myles

    2011-01-01

    We refine internationalization theory by hypothesizing that international expansion is a discontinuous process characterized by an initial ‘big step.’ Firms have to build an infrastructure (e.g., architecture, management systems, and mind-set) to support international operations the first time...... they venture abroad, and subsequent international operations are able to leverage this infrastructure. Thus, we hypothesize that the internationalization process is characterized by: (1) firms taking a long period to make their first international investment; and (2) firms taking shorter but constant periods...... for subsequent investments. We examine the international expansion activities of 176 Danish firms and find support for these arguments....

  1. Procedural Rationality in the Decision-Making of Internationalizing SMEs

    DEFF Research Database (Denmark)

    Hsieh, Linda; Elbanna, Said; Narooz, Rose

    This paper contributes to the growing body of empirical work on how SME decision-makers decide to internationalize in two ways: first, it responds to recent calls for incorporating strategic decision-making literature into understanding SME internationalization decisions. Second, it provides a be...... a more rational decision-making procedure when they perceive a high level of international risk. The evidence also suggest that internationalization performance, planned internationalization, credit check, and decision team size are positively related to procedural rationality....... a better understanding of under what circumstances, SME decision-makers tend to follow a more rational approach toward internationalization decisions. Specifically, this paper examines a set of contextual variables (the level of perceived international risk, internationalization performance, planned versus...... ad hoc internationalization, credit check, distribution adaptation, and decision team size) and their influence on the extent of procedural rationality in SME internationalization decision-making process. The findings from a sample of 176 export-active SMEs show that decision-makers tend to follow...

  2. Internationalization manager’s identity and authority identification:staffing of the export department in Greek internationalized manufacturing companies

    OpenAIRE

    Garri, Myropi; Konstantopoulos, Nikolaos

    2011-01-01

    The research objective of this paper is to examine the staffing procedure of the internationalization department of the company in reference to the origin of the individuals selected to compose it. Subsequently, we endeavour to outline the identity of the individual at the head of internationalization, where a special department doesn’t exist. Additionally, we attempt to recognize the overall responsibilities and authority spaces of the internationalization manager. Results implied the prefer...

  3. Internationalization of Chinese Higher Education

    Science.gov (United States)

    Chen, Linhan; Huang, Danyan

    2013-01-01

    This paper probes into the development of internationalization of higher education in China from ancient times to modern times, including the emergence of international connections in Chinese higher education and the subsequent development of such connections, the further development of internationalization of Chinese higher education, and the…

  4. Internationalization and Performance of Retail Firms

    DEFF Research Database (Denmark)

    Assaf, A. George; Josiassen, Alexander; T. Ratchford, Brian

    2012-01-01

    retailers through facilitating the transfer of learning in international markets. The study innovates by introducing a new performance metric, and an advanced methodology to account for the dynamic aspects of organizational learning. Testing our hypotheses on a sample of international retailers, we find......This paper offers a fresh approach to the literature examining the effect of internationalization on retail-firm performance. We draw on the organizational learning theory to test the moderating effect of four variables which are hypothesized to affect the performance of internationalizing...... that the relationship between internationalization and performance is U-shaped, and moderated by mergers and acquisitions, age at entry to international markets and country of origin. The findings extend prior research by providing more comprehensive evidence regarding the conditions under which internationalization...

  5. Internationalization and Hotel Performance

    DEFF Research Database (Denmark)

    Assaf, Albert G.; Josiassen, Alexander; Oh, Haemon

    2016-01-01

    Few industries are as inherently international as the hotel industry. This article sets out to investigate the impact of internationalization on performance in the hotel industry. Building on the theory of organizational learning the authors test several hypotheses regarding the shape of the inte......Few industries are as inherently international as the hotel industry. This article sets out to investigate the impact of internationalization on performance in the hotel industry. Building on the theory of organizational learning the authors test several hypotheses regarding the shape...... of the internationalization–performance relationship as well as the impact of four moderating variables. In line with the research aim and the underlying dynamism of organizational learning theory, these hypotheses are tested using a dynamic Bayesian model. The results indicate that internationalization has a U-shaped impact...

  6. Rapid and simple determination of polyphyllin I, II, VI, and VII in different harvest times of cultivated Paris polyphylla Smith var. yunnanensis (Franch.) Hand.-Mazz by UPLC-MS/MS and FT-IR.

    Science.gov (United States)

    Wu, Zhe; Zhang, Ji; Xu, Furong; Wang, Yuanzhong; Zhang, Jinyu

    2017-01-01

    Paris Polyphylla Smith var. yunnanensis (Franch.) Hand.-Mazz ("Dian Chonglou" in Chinese) is a famous herbal medicine in China, which is usually well known for activities of anti-cancer, hemolysis, and cytotoxicity. In this study, Fourier transform infrared (FT-IR) spectroscopy coupled with principal component analysis (PCA) and partial least-squares regression (PLSR) was applied to discriminate samples of P. polyphylla var. yunnanensis harvested in different years and determine the content of polyphyllin I, II, VI, and VII in P. polyphylla var. yunnanensis. Meanwhile, ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) was used to study the dynamic changes of P. polyphylla var. yunnanensis harvested in different years (4, 5, 7, 8, 9, 12, and 13 years old). According to the UPLC-MS/MS result, the optimum harvest time of P. polyphylla var. yunnanensis is 8 years, due to the highest yield of four active components. By the PCA model, P. polyphylla var. yunnanensis could be exactly discriminated, except that two 8-year-old samples were misclassified as 9-year-old samples. For the prediction of polyphyllin I, II, VI, and VII, the quantitative results are satisfactory, with a high value for the determination coefficient (R 2 ) and low values for the root-mean-square error of estimation (RMSEE), root-mean-square error of cross-validation (RMSECV), and root-mean-square error of prediction (RMSEP). In conclusion, FT-IR combined with chemometrics is a promising method to accurately discriminate samples of P. polyphylla var. yunnanensis harvested in different years and determine the content of polyphyllin I, II, VI, and VII in P. polyphylla var. yunnanensis.

  7. SME Internationalization Intelligence Information and Knowledge on International Opportunities

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    Zizah Che Senik

    2014-12-01

    Full Text Available Small and medium enterprises (SMEs internationalization intelligence, referring to the process of gathering information and knowledge on international opportunities, is crucial to initiate SMEs’ internationalization. The literature has stressed organizational resources, networks and information sharing as means to acquire internationalization intelligence, suggesting that the resource-based, network and social capital perspectives can be adopted to explore this issue. However, previous literature still lacks evidence on how SMEs acquire relevant intelligence, and who or what are involved with the process. To address this lack of evidence, we interviewed 54 SME owners/key personnel in the manufacturing sector to: identify sources of internationalization intelligence; examine how those sources assist SMEs to internationalize; and develop propositions on internationalization intelligence. Analyzing the data using NVivo, four themes emerged including institutions, business associates, personal efforts, and other means. The analysis suggests internationalization intelligence occurs mainly through the networks of the SME owners/key personnel, built on their firm’s resources through their internal and external information sharing activities, indicating the need of the SMEs to position themselves in their environments. These findings are developed into propositions. The study indicates multiple perspectives in conceptualizing the process of internationalization intelligence. This study advances a conceptualization of internationalization intelligence, and offers avenues for future research.

  8. Training for Internationalization through Domestic Geographical Dispersion

    DEFF Research Database (Denmark)

    Santangelo, Grazia D.; Stucchi, Tamara

    Traditionally created to deal with the unfriendly domestic environment, business groups (BGs) are increasingly internationalizing. However, how BGs can reconcile their strictly domestic orientation with an international dimension still remains an open question. Drawing on arguments from...... organizational learning, we seek to solve this puzzle in relation to the internationalization of Indian BGs. In particular, we argue that in heterogeneous domestic emerging markets BG’s geographical dispersion across sub-national states provides training for internationalization. To internationalize successfully......, BGs need to develop the capability of managing geographically dispersed units in institutional heterogeneous contexts. Domestic geographical dispersion would indeed help the BG dealing with different regulations, customers and infrastructures. However, there is less scope for such training as BGs...

  9. Internationalization of Emerging Economies and Firms

    DEFF Research Database (Denmark)

    A contribution to the scarce body of literature on internationalization of emerging economies and their firms. Using a large variety of national contexts, it addresses the advancing business development of new emerging economies and their impact on the process of internationalization of emerging...

  10. Strategic entrepreneurial internationalization : A normative framework

    NARCIS (Netherlands)

    Autio, Erkko

    Much of the literature on international new ventures (INVs) tends to focus on early internationalization and view it as the expression of firm-specific advantages that existed prior to internationalization. This paper presents a normative framework that articulates how INVs can leverage

  11. The Identity of Ownership on Firm Internationalization

    DEFF Research Database (Denmark)

    Strandskov, Jesper; Madsen, Tage Koed; Pedersen, Bent

    2016-01-01

    The paper develops an integrative ownership-internationalization model that explores the influences of various owner types (i.e. investor-owned firms, family-owned firms, employee-owned firms, cooperative–owned firms, and state-owned firms) on firm internationalization. Based on a comparative...... analysis of the various owner types, we discuss how each owner group’s main objectives, risk behavior and provision of resources influence their internationalization strategies and decisions (i.e. scale, scope and speed decisions)....

  12. The Role of Firm Ownership on Internationalization

    DEFF Research Database (Denmark)

    Hobdari, Bersant; Gregoric, Aleksandra; Sinani, Evis

    2011-01-01

    This paper investigates how different types of owners influence the extent of firm internationalization, measured by the share of firm exports in total sales. The results of the analysis carried out using firm level data of Estonian and Slovenian firms, show that the firms under the control...... in internationalization process. Finally, high market share also leads to increased internationalization through exports as firms seek to expand in foreign markets after having dominated the domestic ones....

  13. Internationalization and Firm Performance in Agribusiness: Empirical Evidence from European Cooperatives

    Directory of Open Access Journals (Sweden)

    Matthias Heyder

    2011-10-01

    Full Text Available  The ongoing internationalization of markets has become a major issue also for companies of the agribusiness. Nevertheless, neither the degree of internationalization of agribusiness firms nor the internationalization-performance relationship in the agribusiness sector have been analyzed thoroughly so far. To help fill this void, we use panel data compiled from annual reports and balance sheets to investigate the internationalization as well as the internationalization-performance relationship of 21 leading European cooperatives in the dairy and meat sectors. Our results indicate that internationalization has a significant positive impact on firm performance.

  14. On the Internationalization of Corporate Boards

    DEFF Research Database (Denmark)

    Oxelheim, Lars; Gregoric, Aleksandra; Randøy, Trond

    2013-01-01

    This study investigates the internationalization of corporate boards, using a sample of 346 non-financial listed Nordic firms during 2001-2008. Given a high level of international activity, these firms have surprisingly few foreign directors. The picture of international expertise changes...... considerably, however, if we also count the international experience of national directors. The percentage of foreign directors is related primarily to financial internationalization rather than foreign sales, and thus presumably to the monitoring rather than advisory functions. The international experience...... of the nationals covaries with foreign sales, and increases with the share of foreign directors. Thus both sources of international expertise should be considered when analyzing board internationalization....

  15. The Internationalization of Teacher Education: Different Contexts, Similar Challenges

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    Bruno Leutwyler

    2017-05-01

    Full Text Available This is a comparative study focused on the internationalization of teacher education in three countries – Bulgaria, Switzerland, and South Africa. The authors stress on the fact that on the one hand, teacher education is exposed to the increasing imperative to internationalize but on the other hand, teacher education is traditionally to a very large extent nationally shaped. The classical fields of internationalization of teacher education – individual mobility of students and staff, program and provider mobility, internationalization of the curriculum, internationalization of the campus, international cooperation – are used as a basis for constructing the chapter. The authors present these fields in teacher education in Bulgaria, Switzerland, and South Africa. Then, comparing the three different national contexts, some common features, similarities and differences between the countries are analyzed. Finally, the study ends with synthesizing two main challenges that illustrate how an appropriate internationalization of teacher education is still to be developed.

  16. Internationalization and Firm Performance in Agribusiness: Empirical Evidence from European Cooperatives

    OpenAIRE

    Heyder, Matthias; Makus, Christian; Theuvsen, Ludwig

    2011-01-01

     The ongoing internationalization of markets has become a major issue also for companies of the agribusiness. Nevertheless, neither the degree of internationalization of agribusiness firms nor the internationalization-performance relationship in the agribusiness sector have been analyzed thoroughly so far. To help fill this void, we use panel data compiled from annual reports and balance sheets to investigate the internationalization as well as the internationalization-performance relati...

  17. Internationalization in schools - perspectives of school leaders

    DEFF Research Database (Denmark)

    Egekvist, Ulla Egidiussen; Lyngdorf, Niels Erik; Du, Xiangyun

    2017-01-01

    This paper explores how internationalization ideas in primary and lower secondary schools can be developed through the acquisition of international experience abroad by leaders. The study was inspired by existing literature on internationalization and leadership, and theories of experiential...... learning and reflection. Empirically, qualitative material was derived from a study of nineteen Danish school leaders participating in an eight-day delegation visit to China. This study shows that international experience for leaders can be used to develop ideas for internationalization at the school level...

  18. A Dynamic Systems Approach to Internationalization of Higher Education

    Science.gov (United States)

    Zhou, Jiangyuan

    2016-01-01

    Research shows that internationalization of higher education is a process rather than an end product. This paper applies the Dynamic Systems Theory to examine the nature and development of internationalization of higher education, and proposes that internationalization of higher education is a dynamic system. A dynamic framework of…

  19. Extraction of Tc(VII) and Re(VII) on TRU resin

    Energy Technology Data Exchange (ETDEWEB)

    Guerin, Nicolas; Riopel, Remi; Kramer-Tremblay, Sheila [Canadian Nuclear Laboratories (CNL), Chalk River, ON (Canada). Radiobiology and Health Branch; De Silva, Nimal; Cornett, Jack [Ottawa Univ., ON (Canada). Dept. of Earth and Environmental Sciences; Dai, Xiongxin [China Institute for Radiation Protection, Beijing (China)

    2017-06-01

    TRU resin can be used to rapidly and selectively extract Tc(VII) and Re(VII). The retention capacity curves of Tc(VII) and Re(VII) for HNO{sub 3}, HCl, H{sub 2}SO{sub 4} and H{sub 3}PO{sub 4} solutions were studied and prepared. Tc(VII) and Re(VII) were simultaneously extracted in 2 M H{sub 2}SO{sub 4} and 1.5 M H{sub 3}PO{sub 4} and were effectively separated from Mo(VI) and Ru(III). Tc(VII) and Re(VII) remained strongly bonded to the resin even after washing using a large volume of 2 M H{sub 2}SO{sub 4} at a relatively high flow rate. Also, they were both completely eluted from the resin using 15 mL of near boiling water, an eluent directly compatible for ICP-MS instrument measurements.

  20. Monoclonal antibodies to human factor VII: a one step immunoradiometric assay for VII:Ag.

    OpenAIRE

    Takase, T; Tuddenham, E G; Chand, S; Goodall, A H

    1988-01-01

    Three mouse monoclonal antibodies (RFF-VII/1, RFF-VII/2, and RFF-VII/3) which bind specifically to different epitopes on human factor VII antigen were raised. Two of the antibodies, RFF-VII/1 and RFF-VII/2, bound strongly to factor VII antigen (VII:Ag), but only RFF-VII/1 and RFF-VII/3 were potent inhibitors of factor VII coagulation activity (VII:C). RFF-VII/1 and RFF-VII/2 were used in a one step, double monoclonal immunoradiometric assay for VII:Ag. This was highly reproducible and detecte...

  1. Factors determining early internationalization of entrepreneurial SMEs: Theoretical approach

    Directory of Open Access Journals (Sweden)

    Agne Matiusinaite

    2015-12-01

    Full Text Available Purpose – This study extends the scientific discussion of early internationalization of SMEs. The main purpose of this paper – to develop a theoretical framework to investigate factors determining early internationalization of international new ventures. Design/methodology/approach – The conceptual framework is built on the analysis and synthesis of scientific literature. Findings – This paper presents different factors, which determine early internationalization of international new ventures. These factors are divided to entrepreneurial, organizational and contextual factors. We argue that early internationalization of international new ventures is defined by entrepreneurial characteristics and previous experience of the entrepreneur, opportunities recognition and exploitation, risk tolerance, specific of the organization, involvement into networks and contextual factors. Study proved that only interaction between factors and categories has an effect for business development and successful implementation of early internationalization. Research limitations/implications – The research was conducted on the theoretical basis of scientific literature. The future studies could include a practical confirmation or denial of such allocation of factors. Originality/value – The originality of this study lies in the finding that factor itself has limited effect to early internationalization. Only the interoperability of categories and factors gives a positive impact on early internationalization of entrepreneurial SMEs.

  2. To Internationalize Rapidly from Inception: Crowdsource

    Directory of Open Access Journals (Sweden)

    Nirosh Kannangara

    2012-10-01

    Full Text Available Technology entrepreneurs continuously search for tools to accelerate the internationalization of their startups. For the purpose of internationalizing rapidly from inception, we propose that technology startups use crowdsourcing to internalize the tacit knowledge embodied in members of a crowd distributed across various geographies. For example, a technology startup can outsource to a large crowd the definition of a customer problem that occurs across various geographies, the development of the best solution to the problem, and the identification of attractive business expansion opportunities. In this article, we analyze how three small firms use crowdsourcing, discuss the benefits of crowdsourcing, and offer six recommendations to technology entrepreneurs interested in using crowdsourcing to rapidly internationalize their startups from inception.

  3. Mapping Academic Library Contributions to Campus Internationalization

    Science.gov (United States)

    Witt, Steven W.; Kutner, Laurie; Cooper, Liz

    2015-01-01

    This study surveyed academic libraries across the United States to establish baseline data on their contributions to campus internationalization. Supplementing data from the American Council on Education (ACE) on internationalization of higher education, this research measured the level of international activities taking place in academic…

  4. Specifics of the Internationalization Process of Czech Engineering SMEs

    Directory of Open Access Journals (Sweden)

    Lea Kubíčková

    2015-01-01

    Full Text Available The aim of this paper is to define the specifics of the internationalization process of Czech engineering small and medium-sized enterprises (SMEs. Based on primary data collection among Czech engineering SMEs there were defined the main motives of the internationalization. There were also identified the factors subjectively considered by SMEs as the key success factors of the internationalization process. Attention was also paid to subjectively perceived risk factors of the internationalization process and to the issue of risk management in the internationalization process, while it was investigated whether the risk management affects the intensity of export of Czech engineering SMEs. Data were collected via electronic questionnaire surveys conducted in 2011 and 2012. In total 194 respondents (engineering SMEs filled the questionnaires. The obtained data were processed on the basis of descriptive statistics. Moreover hypothesis testing was performed.

  5. Internationalization of the Business Firm: A Literature Review

    OpenAIRE

    Rodríguez Valle, Alejandro

    2011-01-01

    Internationalization of the firm theory remains unfinished business and as a result there remains confusion among the academic community. This paper revises the main currents of thought in the academic world concerning the internationalization of the firm debate. We do a brief diagnosis of the international currents of thought and their impact on the unfinished debate of how to advance the theory of internationalization of the firm. Finally, we offer an agenda of academic work which deals wit...

  6. Risk factors in the internationalization process of SMEs

    Directory of Open Access Journals (Sweden)

    Lea Kubíčková

    2013-01-01

    Full Text Available At the present time characterized by globalizing market, increasing competition, accelerating change and the occurrence of many risks it is necessary for businesses, which want to remain competitive, to be able to respond flexibly to the changes in a timely manner and to identify and manage risks. Companies try to diversify business risks, such as the loss of market share in the domestic market, by entering the foreign markets and participating in international trade. Involvement in the internationalization process cannot be understood only as an opportunity to achieve greater profits and a competitive advantage, it is necessary to consider potential risks accompanying this process, because engaging in the internationalization process may bring the companies many different specific risks. It would be useful for companies to identify the factors of failure resulting from internationalization. Identifying the barriers to internationalization, the main risk factors associated with it and designing their possible prevention or elimination could provide SMEs an impetus to enter foreign markets. Although the risk is a frequently discussed issue in the international discussion, only few studies were strictly focused on risk management in the internationalization process. Risk management is a broad discipline that requires a specific knowledge in practice. However, particularly small and medium-sized enterprises are often unable to identify the potential risks of the internationalization process and therefore are not able to manage the risks. This is due to the fact that SMEs usually do not have managers with a deep knowledge of risk management and, moreover, these managers also often lack experience with foreign markets. Unfortunately, the surveys of SMEs conclude that the poorly predicted risks of entering foreign markets are one of the most common causes of failure of SMEs internationalization process.The main objective of this paper is to identify

  7. The Impact of the Incubator on the Internationalization of Firms

    Directory of Open Access Journals (Sweden)

    Raquel Engelman

    2015-04-01

    Full Text Available This paper aims to examine how technology incubators contribute to the internationalization of incubated Brazilian companies. To do so, was developed a framework that, in addition to supporting research, can be used to provide a basis for studies of internationalization in small technology-based companies and incubators and to assist their managers. By comparing the factors identified as influencing internationalization and the actions and services provided by the technology incubators, an integrated model with four constructs (entrepreneurs; organizational characteristics; network; foreign market was built. The results demonstrate that incubation positively affects the internationalization of companies and indicate the actions and services that contribute towards the internationalization, as also reveals aspects that could be improved.

  8. Internationalization and Localization in Python

    CERN Multimedia

    CERN. Geneva

    2016-01-01

    Internationalization and Localization are increasingly important in an interconnected world. Regardless of that, developers tend to treat them as secondary issues, very often choosing to address them properly when it's already too late. The fact that most programming language standard libraries choose to ignore the matter doesn't help either. In this talk we will present some useful Python libraries and tools that can help you internationalize and localize your code with minimal effort. We will also describe some common pitfalls and problems.

  9. Internationalizing Teacher Education: The Case of Belarus

    Science.gov (United States)

    Lugovtsova, Alena; Krasnova, Tatiana; Torhova, Anna

    2012-01-01

    This article describes the unique characteristics of internationalization in teacher education in the Republic of Belarus, by asking how the creation of a national system of teacher education after the USSR's disintegration has both enhanced and hindered internationalization. The question is answered by providing an overview of the specific…

  10. Activity Specific Knowledge Characteristics in the Internationalization Process

    DEFF Research Database (Denmark)

    Søberg, Peder Veng

    2012-01-01

    /methodology/approach – The paper presents a framework primarily based on knowledge management theory, which is illustrated in relation to interesting cases of four companies that are global leaders. Findings – An R&D knowledge gap still exists in China and India. Differences across business activities exist in terms......Purpose – The purpose of this paper is to investigate differences in the characteristics of knowledge, which is very important for the internationalization of different business activities. In particular, the focus is on internationalization in emerging markets such as China and India. Design...... of the characteristics of the knowledge, which is most important for the internationalization in emerging markets within multinational corporations (MNCs). The most important knowledge for the internationalization of R&D activities is more tacit than it is for manufacturing activities and international purchasing...

  11. Value Creation Logics and Internationalization of Service Firms

    DEFF Research Database (Denmark)

    Ørberg Jensen, Peter D.; Petersen, Bent

    2014-01-01

    While mainstream theories in international business and management are founded either explicitly or implicitly on studies of manufacturing firms, prior attempts to develop theory on the internationalization of service firms are sparse and have yet to establish solid and comprehensive frameworks...... on a thorough understanding of the fundamental nature of these firms. We put forward ten propositions concerning the pace of internationalization in service firms and the dominant foreign operation modes. The use of value creation logics can be a useful complement to the conventional approaches to the study...... of service firms’ internationalization. However, the fact that most firms encompass more than one value creation logic complicates the use of firm databases and industry statistics. The study presents a novel theoretical approach and a set of propositions on service firm internationalization founded...

  12. Internationalization versus Localization: "The Case of Primary Education in Taiwan"

    Science.gov (United States)

    Wang, Li-Ping; Ho, Hsuan-Fu

    2012-01-01

    Internationalization is receiving increasing attention at academic institutions all over the world. Taiwan is no exception, where the government is promoting internationalization not only in higher education, but also at the primary education level. In this research we identified the key factors of the internationalization of primary education in…

  13. Internationalization of healthcare applications: a generic approach for PACS workstations.

    Science.gov (United States)

    Hussein, R; Engelmann, U; Schroeter, A; Meinzer, H P

    2004-01-01

    Along with the revolution of information technology and the increasing use of computers world-wide, software providers recognize the emerging need for internationalized, or global, software applications. The importance of internationalization comes from its benefits such as addressing a broader audience, making the software applications more accessible, easier to use, more flexible to support and providing users with more consistent information. In addition, some governmental agencies, e.g., in Spain, accept only fully localized software. Although the healthcare communication standards, namely, Digital Imaging and Communication in Medicine (DICOM) and Health Level Seven (HL7) support wide areas of internationalization, most of the implementers are still protective about supporting the complex languages. This paper describes a generic internationalization approach for Picture Archiving and Communication System (PACS) workstations. The Unicode standard is used to internationalize the application user interface. An encoding converter was developed to encode and decode the data between the rendering module (in Unicode encoding) and the DICOM data (in ISO 8859 encoding). An integration gateway was required to integrate the internationalized PACS components with the different PACS installations. To introduce a pragmatic example, the described approach was applied to the CHILI PACS workstation. The approach has enabled the application to handle the different internationalization aspects transparently, such as supporting complex languages, switching between different languages at runtime, and supporting multilingual clinical reports. In the healthcare enterprises, internationalized applications play an essential role in supporting a seamless flow of information between the heterogeneous multivendor information systems.

  14. A born global’s radical, gradual and nonlinear internationalization

    DEFF Research Database (Denmark)

    Vissak, Tiia; Zhang, Xiaotian

    2016-01-01

    a case of a Belarusian door producer that has invested to seven and exported to 11 more countries, we conclude that a home country’s political, economic environment can be a crucial ‘push’ factor for a firm’s fast internationalization but, thereafter, it can internationalize gradually due to lacking...... knowledge or other resources, and de-and re-internationalize due to various internal and, or external reasons. © Rainer Hampp Verlag....

  15. Study of brazilian franchises internationalization: challenges and barriers

    Directory of Open Access Journals (Sweden)

    Helena Loffredo da Rocha Leite

    2014-06-01

    Full Text Available The goal of this study was to analyze brazilian franchises internationalization through a case study, in order to identify the factors that influence internationalization, the adaptations of marketing strategies and main barriers and challenges of brazilian franchises internationalization. A qualitative exploratory research was developed through the case study method. The information was colected via observation and semi-structured interviews with managers in charge of international expansion of two companies. A comparative analysis between obtained data and the theoretical background was made. The results found showed that the studied companies expanded internationally due to external demands and the desire to explore new markets. Changes in marketing strategies were made in different degrees, and communication was the element that suffered greater changes. The main challenge of internationalization found, was to understand local culture and incorporate it into the company’s operations.

  16. Levels of Internationalization in the Container Shipping Industry

    DEFF Research Database (Denmark)

    Gadhia, Hitesh Kumar; Kotzab, Herbert; Prockl, Günter

    2011-01-01

    This paper examines the internationalization level of the world’s largest container shipping companies by examining their port networks. The results of our analysis show that only three of the nineteen companies could be considered as being truly ‘International’ and service the ‘lion’s share......’ of the major and minor ports distributed across the globe. The port networks of the other companies in our survey, whilst having individualized features, shared common characteristics. Guided by the ‘Uppsala Model of Incremental Internationalization’ (Johanson and Vahlne, 1977), we were able to identify four...... internationalization levels of a container shipping company that are indicated by their port network. We argue that the port network plays an additional role as it contributes to the internationalization level of the container shipping companies. This is important because the internationalization level affects...

  17. The Co-evolution of Internationalization and Technological Knowledge

    DEFF Research Database (Denmark)

    Geisler Asmussen, Christian; Hashai, Niron; Delios, Andrew

    2011-01-01

    but diminishing effect of technological knowledge on internationalization and vice versa. This relationship leads to equilibrium in the technological knowledge-internationalization space that dictates the patterns of technological and international evolution of MNEs. The model offers an integrative approach...

  18. Internationalization of Small and Medium Enterprises in the Halal Food Industry

    OpenAIRE

    Ho, Kwok Kheong

    2011-01-01

    Internationalization topics have been widely discussed in past literature. This research has been created to complement internationalization researches around the world and the aim of it is to find out barriers faced by Malaysian SMEs in particular of those in the Halal food industry and the strategies undertaken to overcome the barriers. The research also has a brief overview on the internationalization theories including those that are in the rapid internationalization category. The overvie...

  19. Platforms for Innovation and Internationalization

    DEFF Research Database (Denmark)

    Rasmussen, Erik Stavnsager; Petersen, Nicolaj Hannesbo

    2017-01-01

    The high-tech global startup has many challenges related to both innovation and internationalization. From a Danish cluster of Welfare Tech firms, eight innovative and international firms were selected and interviewed. Such firms typically have to be agile and operate in virtual networks in almost...... all parts of their value chains. This article contributes to the understanding of how innovation and internationalization to a great extent are interlinked. The firms have developed a core product or service offering, which the firms often describe as “a platform”. Around the platform, they develop...

  20. The Influence of Ownership on Firm Internationalization: A Synthesis

    DEFF Research Database (Denmark)

    Strandskov, Jesper; Madsen, Tage Koed; Petersen, Bent

    2018-01-01

    The paper develops an integrative ownership-internationalization model that explores the influences of various owner types (i.e. investor-owned firms, family-owned firms, employee-owned firms, cooperative–owned firms, and state-owned firms) on firm internationalization. Based on a comparative...... analysis of the various owner types, we discuss how each owner group’s main objectives, risk behavior and provision of resources influence their internationalization strategies and decisions (i.e. scale, scope and speed decisions)....

  1. In Search of New Relationship between Internationalization and Firm Performance

    DEFF Research Database (Denmark)

    Wehrmann, Carsten; Turcan, Romeo V.

    diversification. Following the above criticism, this paper provides a different way of measuring the impact of internationalization on firm performance. The group comparison of multi-national and international companies based on financial data show that the reasons for internationalization are not cost advantages......, economies of scale or others frequently mentioned in internationalization research. Instead, this paper identifies an effects of internationalization, which is labeled financing advantage. MNEs can generate disproportional higher revenue growth and higher cash flows than IEs. Therefore, they have more...... equity capital to invest and are thus not exposed to interest change risks to finance growth....

  2. Analysis of the Internationalization Process of a Venezuelan Company

    Directory of Open Access Journals (Sweden)

    Rosângela Sarmento da Silva

    2013-04-01

    Full Text Available This paper aimed to analyze, under the perspectives of economic and organizational behavior theories, the case of the internationalization of Agrogilca, a Venezuelan company classified as an small and medium business, which operates in the mining segment, agricultural materials and building materials. This is an instrumental case study, which had as sources of evidence the examination of documents provided directly by company’s directors and interviews with its owner and employees. For the data analysis and interpretation, it was took the procedure of adaptation to the theory, since the data obtained empirically were contrasted to elements of already consolidated theories about internationalization of companies. It is concluded that the strategy adopted by Agrogilca company is very close to Theory of Market Power proposed by Hymer, in which companies tend to intensify its position abroad and expand their operations. Its internationalization process did not occur according to the Uppsala model, in which the gradualism of relationship matches the gradualism of internationalization processes, but only with exportations that make companies intensify its position abroad, and finally, shows proximity to the internationalization strategy of Multidomestic Theory of Hoskisson. This is because this theory considers as an internationalization cause the sectoral conditions, political structures and customer needs for a greater administrative performance and competitiveness of the company.

  3. Internationalization of Boost Juice to Malaysia

    OpenAIRE

    Jane L. Menzies; Stuart C. Orr

    2014-01-01

    This case describes the process that the Australian juice retail chain, Boost Juice, has used to internationalize to Malaysia. The main objective of this case is to demonstrate good practice in regard to internationalization. The case provides the background of the juice bar industry in Malaysia and determines that it is an attractive market for new start-up juice bars. An analysis of Boost Juice's capability determined that the company utilized the skills of its staff, product innovations, b...

  4. The internationalization of the electricity industry

    International Nuclear Information System (INIS)

    Gulli, F.; Indigenti, S.; Ninni, A.

    1998-01-01

    During the last years the evolution of the electricity industry has been featured by a marked development of the internationalization processes. Several companies started huge foreign investment programmes; construction of power plants; acquisition of generation, distribution and integrated companies. The goal of this study is to analyse the determinants in the internationalization process of the world electricity industry. This topic is introduced in the first, part with a hint on the main theoretical contributions regarding the companies internationalization. In the second part, an attempt is made to define the size of the phenomenon adopting the results yielded by a detailed inquiry about the international strategies of the leading electric companies. In the third part, an econometric analysis, referring to a significant sample of electric companies, is aimed at identifying the main determining factors affecting the international development is mainly due to both organization and regulation of the single national markets [it

  5. Internationalization of SMEs

    DEFF Research Database (Denmark)

    Moini, Hamid; Kuada, John Ernest

    2017-01-01

    central finding is that ownership, management decision making styles, location of firms as well as institutional policies are among the key variable in understanding the resource leveraging processes that shape the internationalization paths of small businesses. We also found that firms with aggressive...

  6. Internationalization in schools - perspectives of school leaders

    DEFF Research Database (Denmark)

    Egekvist, Ulla Egidiussen; Lyngdorf, Niels Erik; Du, Xiangyun

    2017-01-01

    This paper explores how internationalization ideas in primary and lower secondary schools can be developed through the acquisition of international experience abroad by leaders. The study was inspired by existing literature on internationalization and leadership, and theories of experiential...... through reflections of lived experiences, participation in meaningful activities, and active engagement in interaction with international and local colleagues. However, the realization of ideas depends on various elements, including leadership, teacher engagement, policy support, and financial support....... learning and reflection. Empirically, qualitative material was derived from a study of nineteen Danish school leaders participating in an eight-day delegation visit to China. This study shows that international experience for leaders can be used to develop ideas for internationalization at the school level...

  7. Internationalization of small and medium-sized enterprises

    Directory of Open Access Journals (Sweden)

    Zoran Paunović

    2010-06-01

    Full Text Available Highly developed countries, which are similar to Croatia by size and population, highlight the importance of small and medium-sized enterprises (SMEs as holders of export activities and key factors in raising the competitiveness of the entire economy. In this paper authors research the concept of internationalization of SMEs. Analyzing the influence of decision makers on the process of internationalization and showing its advantages and disadvantages for the respective company and country, this research introduces the most common models on the basis of which this process is implemented in practice. A case study of a small export company from Croatia illustrates the process of internationalization to the U.S. market and provides useful information to the companies which are planning to enter new markets.

  8. Globalization/s: Reproduction and Resistance in the Internationalization of Higher Education

    Science.gov (United States)

    Beck, Kumari

    2012-01-01

    Internationalization of higher education has become a significant feature of the Canadian educational landscape. Considered to be a product of and response to globalization, internationalization is being critiqued for having an economic orientation. This paper will begin with a brief overview of internationalization research in Canada, and the…

  9. Discrimination of Wild Paris Based on Near Infrared Spectroscopy and High Performance Liquid Chromatography Combined with Multivariate Analysis

    Science.gov (United States)

    Zhao, Yanli; Zhang, Ji; Yuan, Tianjun; Shen, Tao; Li, Wei; Yang, Shihua; Hou, Ying; Wang, Yuanzhong; Jin, Hang

    2014-01-01

    Different geographical origins and species of Paris obtained from southwestern China were discriminated by near infrared (NIR) spectroscopy and high performance liquid chromatography (HPLC) combined with multivariate analysis. The NIR parameter settings were scanning (64 times), resolution (4 cm−1), scanning range (10000 cm−1∼4000 cm−1) and parallel collection (3 times). NIR spectrum was optimized by TQ 8.6 software, and the ranges 7455∼6852 cm−1 and 5973∼4007 cm−1 were selected according to the spectrum standard deviation. The contents of polyphyllin I, polyphyllin II, polyphyllin VI, and polyphyllin VII and total steroid saponins were detected by HPLC. The contents of chemical components data matrix and spectrum data matrix were integrated and analyzed by partial least squares discriminant analysis (PLS-DA). From the PLS-DA model of NIR spectrum, Paris samples were separated into three groups according to the different geographical origins. The R2X and Q2Y described accumulative contribution rates were 99.50% and 94.03% of the total variance, respectively. The PLS-DA model according to 12 species of Paris described 99.62% of the variation in X and predicted 95.23% in Y. The results of the contents of chemical components described differences among collections quantitatively. A multivariate statistical model of PLS-DA showed geographical origins of Paris had a much greater influence on Paris compared with species. NIR and HPLC combined with multivariate analysis could discriminate different geographical origins and different species. The quality of Paris showed regional dependence. PMID:24558477

  10. The indirect strategies of internationalization of companies

    Directory of Open Access Journals (Sweden)

    Đorđević Momčilo

    2012-01-01

    Full Text Available The subject of this work are, as mentioned in the title, the indirect strategies of internationalization of companies. The first part talks about the new business environment, the factors that lead to changes and their implications. It is at the same time the business context, which must be taken into consideration that determines the success of companies in the new business environment. In this paper, the emphasis is on company business in international markets, and the selection of appropriate strategies of internationalization, which will be responsible for this new business environment. There are many reasons that are discussed in this paper, and would rather indicate that partners from different countries to accept different strategies, rather than opting for a strategy of export, or a strategy of direct investments abroad. The dynamic technical and technological development, and its universal impact, among other relevant factors, put in the first place the importance of different strategies which is achieved through technology transfer, knowledge and experience whereby the exports, as a classic strategy of involvement in international trade, becomes significantly more difficult. Also, the internationalization of enterprises through direct investment abroad, involves many difficulties related to fitting in a foreign enterprise environment, and a high risk strategy. In addition, there is still a large number of countries do not allow wholly owned foreign enterprises. The paper discusses the value of various indirect internationalization strategy, which may be useful for those domestic companies that are in front of problem the choice of acceptable strategies of internationalization.

  11. Internationalization and firm performance in Chindia countries: a meta-analytic review

    Directory of Open Access Journals (Sweden)

    LINDA SCHULZE

    Full Text Available For more than four decades, researchers have examined theoretically and empirically the relationship between internationalization and firm performance. While existing studies have provided important contributions, the stream of research still lacks consistency due to ambiguous findings on the internationalization-firm performance relationship. Moreover, previous research has often been limited to developed countries. The present study focuses on the emerging Chindia countries and determines the direction and the strength of the internationalization-firm performance relationship. Additionally, we have identified moderators of the relationship. Drawing on 21 studies, based on 9026 firms, we utilize a meta-analytic review to assess our hypotheses. Our results show that there is a significant and positive internationalization-firm performance relationship in Chindia countries. The effect of internationalization in India and China does not significantly differ. Moreover, we find that the effect of internationalization is significantly stronger in the United States as compared to the Chindia countries. The time period of data collection did not play an important role as a moderator. The present study contributes to the International Business literature by examining how and to which extent internationalization influences firm performance and offers implications for theory and practice as well as recommendations for future research.

  12. The tangible and intangible Processes of Internationalization: the Argentinean SMEs

    Directory of Open Access Journals (Sweden)

    Christian Keen

    2013-12-01

    Full Text Available This study reviews the concepts of tangible and intangible internationalization using a data from Argentinean SMEs. The findings suggest that managers may have to make a strategic commitment to upgrade and expand firms’ resources and capabilities to achieve long term internationalization. The results offer evidence that becoming an international company is not only about having a physical presence in a foreign market. It is important to re-focus the firms’ outlook from competing in a protected domestic market to competing in markets with a strong presence of international companies. In addition, managers may have to shift their focus from short-term rent and profit seeking to long-term internationalization. This research also contributes to the study of internationalization of SMEs as it further expands the concept of internationalization by including a long-term perspective where the company can be international without having a physical presence in a foreign market

  13. The Internationalization of Brazilian Design Firms: What do We Know?

    Directory of Open Access Journals (Sweden)

    Melissa Senra

    2014-12-01

    Full Text Available This study investigates the internationalization process of Brazilian brand design firms. The following research question inspired the study: What are the characteristics of the internationalization of these firms? The study, of a technical nature, is based on secondary sources, complemented by personal interviews with specialists. The results show that the design sector in Brazil is still very fragmented, and that internationalization of design firms is incipient. 

  14. Effects of Internationalization on Ownership Structure: Evidence from Latin American Firms

    Directory of Open Access Journals (Sweden)

    Hsia Hua Sheng

    2014-07-01

    Full Text Available We analyze the direct and simultaneous effects of internationalization on the ownership structure of Latin American companies based on agency theory. Using a sample of 425 Latin American firms between 2007 and 2011, which corresponds to 1,776 observations, we use random effects and three-stage least squares panel data regression to test these effects. We find that the hypothesized positive effect of internationalization on ownership concentration is rejected. Our results support the negative relationship that is predicted by principal-agent theory when analyzing the effect of ownership on the degree of internationalization. Greater internationalization via the equity entry mode is associated with lower levels of ownership concentration. Finally, there is simultaneity in the determination of the relationship between the degree of internationalization and ownership concentration.

  15. AN ANALYSIS OF THE CONCEPT OF LEARNING FROM THE INTERNATIONALIZATION PERSPECTIVE

    Directory of Open Access Journals (Sweden)

    Cyntia Vilasboas Calixto

    2012-01-01

    Full Text Available The present study aims to analyze the concept of learning in the internationalization studies. Considering the relationship between learning and internationalization had its groundwork at the Uppsala University, we believe its relevant outlining the path from the main publications regarding the Uppsala School as well as the internationalization process model developed by them in order to comprehend the evolution of the concept of learning from this perspective. In addition, owing to the extension of the relationship between learning and internationalization, this paper analyzes some relevant organizational learning studies and their contributions in order to construe the internationalization process development. Therefore, the contribution of this study is the critical review on the concept of learning from the Uppsala School and also indicating contributions of this concept from the latest developments of this idea.

  16. The Internationalization of Small and Medium Enterprises and Human Capital

    Directory of Open Access Journals (Sweden)

    Laura Godelytė

    2015-05-01

    Full Text Available Small and medium enterprises (SME’s are generally recognised as a factor, which influences economic growth and impacting competitiveness of country. In the context of globalization the impact of internationalization of SME’s is increasing and determines development of new technologies. The internationalization of SME’s is determined to a large extent by the human capital of entrepreneurs/managers. The aim of this article is to analyse and summarise elements of human capital, that are discussed in scientific literature and to distinguish the most important for SME’s internationalization. The research is based on the evaluation of human capital in scientific literature and analysis and synthesis of questions of SME’s internationalization.

  17. luxury marketing: internationalization strategies for brazilian jewelry companies

    Directory of Open Access Journals (Sweden)

    Chaline Gasperini

    2010-04-01

    Full Text Available This article seeks to make an analysis of the luxury market and of Brazilian jewelry companies. The main objective is to analyze the attraction of external marketing to luxury brands internationalization, emphasizing Brazilian jewelry companies. First, the national environment of luxury market an jewelry in Brazil is presented. In sequence, it will address the possible goals, risks and opportunities that internationalized jewelry companies face in the expansion process and its difficulties in foreign markets. Finally, some forms of internationalization will be presented based on the case of the Brazilian jewelry companies H Stern and Talento Jóias. The methodology used in this article is exploratory, with documental analysis and in depth interview. As theoretical foundations for the article, the themes luxury, exportations, company internationalization and global market were addressed. The main author(s researched were: Allérès (2006, Almeida (2007, Czinkota (2001, Grande (2007, Lipovetsky e Roux (2005. Among the main conclusions, Brazilian jewelry companies have great advantages compared to other countries, having the possibility to use Brazilian nature resources, like precious stones and gems, thus, it become more interesting and viable to innovate and conquer external market. Besides, jewelry market attractions make several entrepreneurs interested in opening business in this field, and lately internationalize them, such as H Stern case.

  18. The Impact of the Incubator on the Internationalization of Firms

    OpenAIRE

    Raquel Engelman; Aurora Carneiro zen; Edi Madalena Fracasso

    2015-01-01

    This paper aims to examine how technology incubators contribute to the internationalization of incubated Brazilian companies. To do so, was developed a framework that, in addition to supporting research, can be used to provide a basis for studies of internationalization in small technology-based companies and incubators and to assist their managers. By comparing the factors identified as influencing internationalization and the actions and services provided by the technology incubators, an in...

  19. Lean Internationalization: How to Globalize Early and Fast in a Small Economy

    Directory of Open Access Journals (Sweden)

    Michael Neubert

    2017-05-01

    Full Text Available This study examines the early market internationalization of 32 high-tech startups that operate internationally from small and open economies. It uses a comparative cross-national multiple case study research design to explore how such startups may differ in their speed of internationalization. Based on interviews with the founders, the speed of early market internationalization in these startups increases significantly due to the application of lean market development processes. The findings provide a basis for developing propositions for further comparative studies focusing on the early and fast internationalization of high-tech startups based in emerging and developed markets. The study contributes to the literature on networks, internationalization, and international entrepreneurship.

  20. Internationalization Strategy and Financial Performance in Brazilian Firms

    Directory of Open Access Journals (Sweden)

    Pedro Paulo Mendes Silva

    2011-12-01

    Full Text Available The internationalization of the firm and the appearance of multinational companies are not recent events. The first initiatives to realize businesses overseas and increase profits in this way date from the beginning from the Modern Age. For Brazilian companies in particular, this phenomenon has been gaining attention since the 1990s, with the commercial opening of the country. The objective of this study was to analyze the strategy of internationalization in Brazilian companies, in particular the case of publically traded companies with foreign direct investments greater than $10 million, and the relation with the financial performance of these companies. Through a quantitative study using the rate of variation of internationalization and financial performance, researchers developed an analysis of the relation between the process of internationalization and financial performance indicators in nine companies that make up the non-probabilistic sample of convenience. The results concluded that there is a weak positive correlation with financial indicators of growth; profitability metrics show a negative relationship in some of the independent variables.

  1. E-health internationalization requirements for audit purposes.

    Science.gov (United States)

    Ouhbi, Sofia; Fernández-Alemán, José Luis; Carrillo-de-Gea, Juan Manuel; Toval, Ambrosio; Idri, Ali

    2017-06-01

    In the 21st century, e-health is proving to be one of the strongest drivers for the global transformation of the health care industry. Health information is currently truly ubiquitous and widespread, but in order to guarantee that everyone can appropriately access and understand this information, regardless of their origin, it is essential to bridge the international gap. The diversity of health information seekers languages and cultures signifies that e-health applications must be adapted to satisfy their needs. In order to achieve this objective, current and future e-health programs should take into account the internationalization aspects. This paper presents an internationalization requirements specification in the form of a reusable requirements catalog, obtained from the principal related standards, and describes the key methodological elements needed to perform an e-health software audit by using the internationalization knowledge previously gathered. S Health, a relevant, well-known Android application that has more than 150 million users in over 130 countries, was selected as a target for the e-health internationalization audit method and requirements specification presented above. This application example helped us to put into practice the proposal and show that the procedure is realistic and effective. The approach presented in this study is subject to continuous improvement through the incorporation of new knowledge originating from additional information sources, such as other standards or stakeholders. The application example is useful for early evaluation and serves to assess the applicability of the internationalization catalog and audit methodology, and to improve them. It would be advisable to develop of an automated tool with which to carry out the audit method. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. Small and medium enterprise competitiveness: Internationalization strategy

    OpenAIRE

    Silva, Francisco Maria Branco Cannas Henriques da

    2013-01-01

    Field lab: SME competitiveness This work project has the objective to internationalize a Portuguese fast food chain, named Prego Gourmet, to the Brazilian market, more specifically, to enter in the Sao Paulo fast food industry in the end of 2013, through studies of the internal and external environment. Hence, this work project is a prospective analysis of what the company should do in order to internationalize, analysing the entry mode, collaborative arrangements, and implemen...

  3. The Internationalization of SMEs in Costa Rica

    OpenAIRE

    Leiva Bonilla, Juan Carlos

    2013-01-01

    This article aims to analyze the internationalization process of small and medium enterprises (SMEs) in Costa Rica. Its ultimate goal is to draw conclusions that might enable the various stakeholders in the process (businesses, government, support agencies, and academia) to make decisions based on better information. To do this we will review the current status of this business sector, compare the patterns of internationalization identified in the theory with those experienced by Costa Rican ...

  4. Transnational Academic Mobility, Internationalization and Interculturality in Higher Education

    Science.gov (United States)

    Kim, Terri

    2009-01-01

    The purpose of this paper is to consider the complex relations of transnational academic mobility, internationalization and interculturality in higher education. It is argued that, in the contemporaneous relations of the triad, "interculturality" disappears and the other two--transnational academic mobility and internationalization--are…

  5. Internationalizing curricula : Needs and wishes of alumni and employers with

    NARCIS (Netherlands)

    Jos Walenkamp; Joyce den Heijer; Anneke Schuurmans-Brouwer; A. (Andreas) Funk

    2014-01-01

    Internationalizing curricula. Needs and wishes of alumni and employers with regard to international competencies. Internationalization has become of great importance for universities acrossthe globe. The labour market is becoming international, with internationalopportunities and international

  6. South Korean Higher Education Internationalization Policies: Perceptions and Experiences

    Science.gov (United States)

    Palmer, John D.; Cho, Young Ha

    2012-01-01

    Our study investigates how Korean universities are designing and implementing internationalization policies to meet the demands of globalization. Relying upon globalization theory we reveal how power is embedded within these internationalization efforts. Indeed, we accept the notion that the United States is the world's superpower and therefore…

  7. Firm internationalization from a network-centric complex-systems perspective

    DEFF Research Database (Denmark)

    Chandra, Yanto; Wilkinson, Ian F.

    2017-01-01

    firm internationalization behavior is impossible to predict, aggregate patterns are to some extent. We review existing research on the role of networks in the internationalization process and explain how theories of complexity apply. We also describe three ways in which we can build NCCSI models using...

  8. Internationalization at Harvard

    Science.gov (United States)

    Strong, Ned

    2013-01-01

    The aim of this essay is to describe internationalization at Harvard University. Founded by European colonists in 17th century New England, Harvard has historic international roots. By the mid 1900's it had become an international powerhouse attracting top students, academics and scientists from around the world. Yet, the University is…

  9. INTERNATIONALIZATION OF STATE-OWNED ENTERPRISES THROUGH FOREIGN DIRECT INVESTMENT

    Directory of Open Access Journals (Sweden)

    Fernanda Ribeiro Cahen

    2015-10-01

    Full Text Available State-owned enterprises (SOEs are created to focus on domestic needs, and yet recent evidence points to increasing outward foreign direct investment by SOEs. Existing International Business (IB theories focus on efficiency-based motives for internationalization; therefore, they do not fully capture SOEs’ internalization dynamics, which are driven largely by political factors and social welfare considerations. We integrate public management and IB theories to develop propositions that combine these questions: why SOEs internationalize; what are their motivations; and what are the main managerial outcomes of SOEs’ internationalization. Our findings suggest that SOEs display little hesitancy in entering international markets, and that SOE international expansion is not contradictory with the goals of state-ownership if the purpose is to adjust the company to changing institutional environments both in the domestic and international markets. Our propositions about SOE internationalization are based on an in-depth case study of the outward foreign direct investment conducted by Brazil’s Petrobras over the past three decades.

  10. The Dynamic Internationalization Model of Slovenian Born Global SMEs

    Directory of Open Access Journals (Sweden)

    Ina Lejko

    2013-01-01

    Full Text Available Small and medium sized enterprises (SMEs are important businessactors in the Slovenian, as well as European economy. Inaddition to the current global market conditions, reflecting a severeeconomic downturn, the SMEs in Slovenia and other transitioneconomies operate under additional extensive external pressures,arising from the opening of their domestic markets. Undersuch conditions, companies, including SMEs, perceive internationalizationas an inevitable, or even urgent step in the processof their business operations. However, companies pursue differentpaths in their internationalization efforts, one of them beinga rapid internationalization strategy, denoted as the Born Globalconcept. In the paper, we explore the internationalization processof Slovenian Born Global SMEs. We employ an exploratory qualitativecase study analysis of selected Slovenian SMEs in order tograsp the key characteristics of their internationalization process.On the basis of the latter we construct a dynamic internationalizationmodel that might be used as a conceptual framework forempirical research of dynamic SMEs market behavior in Sloveniaand other transition countries.

  11. Internationalization in schools - perspectives of school leaders

    DEFF Research Database (Denmark)

    Egekvist, Ulla Egidiussen; Lyngdorf, Niels Erik; Du, Xiangyun

    2017-01-01

    through reflections of lived experiences, participation in meaningful activities, and active engagement in interaction with international and local colleagues. However, the realization of ideas depends on various elements, including leadership, teacher engagement, policy support, and financial support.......This paper explores how internationalization ideas in primary and lower secondary schools can be developed through the acquisition of international experience abroad by leaders. The study was inspired by existing literature on internationalization and leadership, and theories of experiential...

  12. A Case Study of an Internationalization Process of a Private Higher Education Institution in Malaysia

    Directory of Open Access Journals (Sweden)

    Abu Bakar Abdul Rahim

    2013-12-01

    Full Text Available The increasing competition and commercialization of higher education has led to the internationalization of Higher Education Institutions (HEIs around the world. While internationalization appears to be inevitable, differences are apparent in its definitions, depth, scope and mode. The main aim of this paper is to assess the internationalization efforts of Malaysian HEIs through a case study on the internationalization process of one private HEI. The case highlights various weaknesses of the internationalization effort in the institution. The symptoms and the causes of the problems in the institution corroborate similar findings in other studies involving the internationalization of HEIs. Suggestions and recommendations are presented to enable other organizations that wish to undertake similar internationalization efforts to learn from the case study institution’s experience.

  13. Monoclonal antibodies to human factor VII: production of immunodepleted plasma for VII:C assays.

    OpenAIRE

    Takase, T; Tuddenham, E G; Chand, S; Goodall, A H

    1988-01-01

    A high affinity monoclonal antibody to factor VII (RFF-VII/1), coupled to sepharose, was used to immunodeplete factor VII from normal plasma. The plasma could be used as a substrate in a one stage coagulation assay and performed as well as, or better than, commercially available factor VII deficient plasma or plasma from congenitally deficient factor VII patients. Plasma from normal donors (n = 20), patients with liver disease (n = 20), and patients receiving warfarin (n = 20), or congenitall...

  14. Different Perspectives on Internationalization Research: A Bibliometric Review

    Directory of Open Access Journals (Sweden)

    João Carvalho Santos

    2015-12-01

    Full Text Available A wealth of research has addressed the internationalization of firms using different theories and conceptual perspectives. This paper examines the extant research on internationalization specifically delving into seven streams of research: Market Power, Evolutionary Model, Internalization & Transaction Cost, Eclectic Paradigm, Resource-Based View, Institutional and International New Ventures & Born Global. Methodologically we conduct a bibliometric review in six leading journals recognized for publishing International Business (IB research, during a forty one year period, from 1970 to 2010. Using citations and co-citations analyses on a sample of 1,459 articles, we sought to better understand the internationalization approaches and how they are interconnected, by examining its growth over time, the most used approaches, the works that have had the greatest impact, and the intellectual interconnections among authors. We conclude that there is no dominant approach in International Business research, albeit the Evolutionary Model has been the most cited - in almost 26% of the extant research, specially the paper– “The internationalization process of the firm: A model of knowledge development and increasing foreign market commitment”, by Johanson and Vahlne (1977. We present a broad discussion and point out limitations and directions for future research.

  15. Venture capital and internationalization

    NARCIS (Netherlands)

    Schertler, A.G.; Tykvova, T.

    Cross-border investments represent a substantial share of venture capital activities. We use a comprehensive dataset on investments worldwide to analyze the internationalization of venture capital financing. We postulate that cross-border activity is shaped by macroeconomic factors in the venture

  16. Internationalization Measures in Large Scale Research Projects

    Science.gov (United States)

    Soeding, Emanuel; Smith, Nancy

    2017-04-01

    Internationalization measures in Large Scale Research Projects Large scale research projects (LSRP) often serve as flagships used by universities or research institutions to demonstrate their performance and capability to stakeholders and other interested parties. As the global competition among universities for the recruitment of the brightest brains has increased, effective internationalization measures have become hot topics for universities and LSRP alike. Nevertheless, most projects and universities are challenged with little experience on how to conduct these measures and make internationalization an cost efficient and useful activity. Furthermore, those undertakings permanently have to be justified with the Project PIs as important, valuable tools to improve the capacity of the project and the research location. There are a variety of measures, suited to support universities in international recruitment. These include e.g. institutional partnerships, research marketing, a welcome culture, support for science mobility and an effective alumni strategy. These activities, although often conducted by different university entities, are interlocked and can be very powerful measures if interfaced in an effective way. On this poster we display a number of internationalization measures for various target groups, identify interfaces between project management, university administration, researchers and international partners to work together, exchange information and improve processes in order to be able to recruit, support and keep the brightest heads to your project.

  17. Network embeddedness in the internationalization of biotechnology entrepreneurs

    OpenAIRE

    Leppäaho, Tanja; Chetty, Sylvie; Dimitratos, Pavlos

    2018-01-01

    This study investigates how entrepreneurs of biotech enterprises embed in domestic and international networks so as to internationalize. We advance a contextual framework of embeddedness of internationalizing entrepreneurs, providing a contribution (i) by synthesizing and applying existing conceptual insights from the networking literature to provide a more culturally sensitive view of getting embedded for international entrepreneurship in the biotech industry and (ii) by adding insights into...

  18. Internationalization Process and Technological Capability Trajectory of Iguaçu

    Directory of Open Access Journals (Sweden)

    Rafael Kuramoto Gonzalez

    2012-07-01

    Full Text Available This article focuses on the influence of the internationalization process in the evolution of technological capability. This implication was studied in Iguaçu between 1967 and 2009. To achieve the proposed goal it was used the Internationalization of Brazilian Export Producer Companies Model, built by Kraus (2006 and the Model of Technological Capabilities in Companies of Emerging Economies, built by Figueiredo (2004. The study found that different stages of internationalization require different functions and different levels of technology. The discussion proposed by this paper found a close association between the process of internationalization and the development of technological capability in the company studied. It can be concluded that for companies of Soluble Coffee to conquer, reach and remain competitive in international markets it should engage efforts to build diverse organizational skills, alliances and technological capabilities.

  19. Prospecting theoretical approaches to understand internationalization of creative economy firms

    Directory of Open Access Journals (Sweden)

    Sílvio Luís de Vasconcellos

    2017-12-01

    Full Text Available We argue that the internationalization process of firms in the creative economy has particular aspects that distinguish it from internationalization of firms in traditional economic sectors. We explore ways in which the international business literature might be helpful for understanding how internationalization takes place in firms whose core business is creation of ideas. We conducted a case study using a focus group technique to investigate a creative economy firm specialized in computer graphics. The firm already does business internationally as a producer of electronic mockup models, but is transitioning to the computer-generated video production industry. Our results suggest that behavioral approaches to international business related to entrepreneurship, as well as country origin effects and networks theory could be useful to expanding knowledge about the internationalization process in such firms, in which creativity is a critical resource.

  20. Internationalizing Student Learning and Development

    Science.gov (United States)

    Roberts, Dennis C.; Komives, Susan R.

    2016-01-01

    Best practices in internationalizing student learning and development require cultural critical analysis before transferring, adapting, hedging, or avoiding existing practices in cross-border applications both in and beyond the classroom.

  1. Internationalization and environmental reporting

    NARCIS (Netherlands)

    Kolk, A.; van Tulder, R.J.M.; Lundan, S.M.

    2004-01-01

    This chapter examines the green face of the world's one hundred largest firms from developed economies by linking degrees of internationalization to (pro)activity on environmental reporting. A bargaining approach, emphasizing intrinsic and extrinsic motivations, is applied to understand why the most

  2. Value Creation Logics and Internationalization of Service Firms

    DEFF Research Database (Denmark)

    Ørberg Jensen, Peter D.; Petersen, Bent

    2014-01-01

    be based on a thorough understanding of the fundamental nature of these firms. Design/methodology/approach - Theoretical study. Findings - We put forward propositions concerning the pace of internationalization and the default foreign operation modes in service firms. Research limitations...... implications - We suggest that managers in service firms should consider primarily the nature of the value creation logic(s) in their firms when deciding and designing an internationalization strategy. Originality/value - The study presents a novel theoretical approach and a set of propositions on service firm....../implications - The use of value creation logics can be a useful complement to the conventional approaches to the study of service firms’ internationalization. However, the fact that most firms encompass more than one value creation logic complicates the use of firm databases and industry statistics. Practical...

  3. Internationalization of infrastructure companies

    Directory of Open Access Journals (Sweden)

    Frederico Araujo Turolla

    2009-03-01

    Full Text Available The decision of infrastructure firms to go international is not a simple one. Differently from firms from most of the sectors, investment requires large amounts of capital, there are significant transaction costs and also involves issues that are specific to the destiny country. In spite of the risks, several infrastructure groups have been investing abroad and have widened the foreign part in the share of the receipts. The study herein proposed is a refinement of the established theory of international business, with support from the industrial organization theory, namely on infrastructure economics. The methodology is theoretical empirical since it starts from two existing theories. Hypotheses relate the degree of internationalization (GI to a set of determinants of internationalization. As of conclusions, with the exception of the economies of density and scale, which did not show as relevant, all other variables behaved as expected.

  4. The Importance of Rationales for Internationalization at a Local Level--University and Individual

    Science.gov (United States)

    Willis, Ian; Taylor, John

    2014-01-01

    This study examines rationales for internationalization at a research intensive university in the UK. Internationalization is often described at a macro level without reaching down to explore the individual motivations that may support or constrain internationalization at a particular institution. The article argues that it is important to…

  5. Chinese firms entering Europe : internationalization through acquistitions and strategic alliances

    NARCIS (Netherlands)

    Zhang, Y.; Duysters, G.M.; Filloppv, S.

    2012-01-01

    Purpose – The purpose of this study is to examine specific use of strategic alliances and acquisitions for Chinese firms to catch-up technologically and to enhance their internationalization competence. Design/methodology/approach – The paper offers a conceptual analysis of internationalization

  6. Chinese firms entering Europe : Internationalization through acquisitions and strategic alliances

    NARCIS (Netherlands)

    Duijsters, G.M.; Zhang, Y.; Filippov, S.

    2012-01-01

    Purpose – The purpose of this study is to examine specific use of strategic alliances and acquisitions for Chinese firms to catch‐up technologically and to enhance their internationalization competence. Design/methodology/approach – The paper offers a conceptual analysis of internationalization

  7. Theoretical Perspectives on the Internationalization of Firms

    DEFF Research Database (Denmark)

    Rask, Morten; Håkonsson, Dorthe Døjbak; Strandskov, Jesper

    2008-01-01

    The purpose of this article is to build a coherent framework of the four main theories relating to the internationalization of firms, in order to facilitate better business teaching and research. Yet, theories of the internationalization of firms are broad and rest on different underlying...... assumptions. With the purpose of clarifying the potential for integration of partial theories and fragments in a more logically connected theoretical area, this article offers a meta-theoretical overview of four perspectives within international business economics: Research and its related background, basic...

  8. The Role of Interpretation in the Internationalization of Smaller Brazilian Firms

    Directory of Open Access Journals (Sweden)

    Rene Eugenio Seifert

    2012-10-01

    Full Text Available This study considers how decision-makers in smaller firms interpret the means and conditions of internationalization, and how different modes of interpretation are likely to inform action choices in this process. Drawing on 58 qualitative interviews with the leaders of Brazilian small and medium-sized enterprises (SMEsin the clothing industry located in the state of Paraná, the results support the contention that different understandings given to the means/conditions of internationalization are associated with different action choices. More specifically, the results indicate that: (a interpretation changes the criteria and parameters by which rational choices on internationalization are made; (b a comprehensive explanation of internationalization on the basis of situational characteristics is likely to be inconclusive without taking into account decision-makers’ interpretations; (c particular meanings given to internationalization are likely to inform choice in different ways, (d managers act on the basis of their inter-subjectively negotiated, shared and sustained reality; and (e investigative proximity with practitioners is pivotal in order to comprehensively account for their interpretations.

  9. Levels of Social Capital in Internationalization

    DEFF Research Database (Denmark)

    Decker, Arnim

    2016-01-01

    This contribution introduces the notion of social capital and discusses integration into the studies on internationalization of smaller firms and entrepreneurs. Integrating social capital into the resource based perspective, we categorize social capital at three levels: firstly, social capital can...... be attributed to individuals, affecting their relationship with the external environment. Secondly, social capital is an inherent property of networks, into which smaller firms and entrepreneurs are embedded. Thirdly, social capital exists at the macro level, where its characteristics and availability varies...... between environments and nations. This contribution attemps to fascilitate the operationalization of social capital for an improved understanding of processes of internationalization of smaller firms and entrepreneurs....

  10. Knowledge acquisition for the internationalization of the smaller firm:Content and sources

    OpenAIRE

    Harris, Simon; Fletcher, Margaret

    2012-01-01

    Internationalization process research emphasizes accumulated experience and networks as sources of knowledge for internationalization. Our understanding, however, as to what this knowledge is in practice for smaller firms, the challenges they face in acquiring it, and how they address those challenges is limited. Integrating organizational learning concepts with our theoretical understanding of the small firm internationalization process, we develop a new framework for understanding knowledge...

  11. ICT as an Effective Tool for Internationalization of Higher Education

    Science.gov (United States)

    Magzan, Masha; Aleksic-Maslac, Karmela

    2009-01-01

    Globalization and new technologies have opened up a global market for education pressuring many institutions to be internationalized. Within mainly descriptive mode of analysis, this study investigates how internationalization of higher education can be facilitated by the effective use of information and communication technologies. Reporting…

  12. Internationalization to prevent the spread of nuclear weapons

    International Nuclear Information System (INIS)

    1980-01-01

    The recent International Nuclear Fuel Cycle Evaluation (INFCE) has concluded that, in a world in which an increasing number of countries are using nuclear energy for peaceful purposes, no technical ways exist to prevent the spread of nuclear weapons. Non-proliferation is a political problem and must, therefore, be solved by political means. The reasons why countries want nuclear weapons - whether to meet their real or perceived security requirements or for political prestige - must be removed. Resolution of regional conflicts would diminish the stimulus for proliferation, while significant nuclear disarmament measures would de-emphasize the role of nuclear weapons in international politics. Meanwhile, institutional arrangements could minimize the risks of nuclear weapon proliferation. One such arrangement could be the internationalization of the sensitive, that is, the most proliferation-prone, elements of the nuclear fuel cycle. This book analyses some of the political, economic, technical and legal issues involved in internationalizing the nuclear fuel cycle. It consists of two parts. Part I is SIPRI's (Stockholm International Peace Research Institute) evaluation of the advantages, as well as the weaknesses, of the existing proposals for internationalization. Part II contains the papers contributed to the SIPRI symposium on 'internationalization of the nuclear fuel cycle', which was held in October/ November 1979. (author)

  13. The decision-making in the internationalization of brazilian franchising chains

    Directory of Open Access Journals (Sweden)

    Nadia Wacila Hanania Vianna

    2014-04-01

    Full Text Available This research aimed to understand how the decision making process regarding the internationalization of Brazilian franchise chains occurred. This work intended to learn the motivation for internationalization, and the methods used in decision-making. The results obtained from two franchise chains revealed the adoption of two different decision processes: one where the decision was induced by an interested party in obtaining the international franchise and the other by the franchisor. The entry modes chosen by these chains were distinct (establishment of a wholly owned unit and a franchised unit; these choices conditioned the following steps in the internationalization process.

  14. Factor VII deficiency

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/000548.htm Factor VII deficiency To use the sharing features on this page, please enable JavaScript. Factor VII (seven) deficiency is a disorder caused by a ...

  15. Internationalizing undergraduate psychology education: Trends, techniques, and technologies.

    Science.gov (United States)

    Takooshian, Harold; Gielen, Uwe P; Plous, Scott; Rich, Grant J; Velayo, Richard S

    2016-01-01

    How can we best internationalize undergraduate psychology education in the United States and elsewhere? This question is more timely than ever, for at least 2 reasons: Within the United States, educators and students seek greater contact with psychology programs abroad, and outside the United States, psychology is growing apace, with educators and students in other nations often looking to U.S. curricula and practices as models. In this article, we outline international developments in undergraduate psychology education both in the United States and abroad, and analyze the dramatic rise of online courses and Internet-based technologies from an instructional and international point of view. Building on the recommendations of the 2005 APA Working Group on Internationalizing the Undergraduate Psychology Curriculum, we then advance 14 recommendations on internationalizing undergraduate psychology education--for students, faculty, and institutions. (c) 2016 APA, all rights reserved).

  16. INTERNATIONALIZATION OF HIGHER EDUCATION IN EMERGING EUROPE. A DIACHRONIC PERSPECTIVE

    Directory of Open Access Journals (Sweden)

    Constantin HALANGESCU

    2015-04-01

    Full Text Available The dynamics and implications of internationalization vary quite considerably among different regions and countries, depending on the history and structure of their Higher Education systems. With a target to become the most competitive and dynamic economy in the world, Europe has scaled academic mobility, partnerships between the European Research Area and the world's top universities. The aim of this paper is to present some considerations regarding the internationalization of academic space in emerging European countries; more specifically it is an analytical review of the opinions on the phenomenon of internationalization in diachronic perspective of its development, in order to distinguish the structural problems at the level of interference, of the internationalization strategies before the economic crisis in the academic phenomenon. It can be a point of view in order to prove (argued by some causal relationship that the academic Emergent Europe manifest itself in a differentiated manner, even if the strategies are common.

  17. EKÜL VII Foorum = VII Forum SKTE / Sven Lillepalu

    Index Scriptorium Estoniae

    Lillepalu, Sven

    2004-01-01

    7. oktoobril toimus hotell Olümpia Alfa saalis EKÜL VII foorum. Ettekanded puudutasid järgmisi teemasid: korteriühistu remondi planeerimine, finantseerimine, nõuanded korteriühistuid puudutava seadusandluse kohta. Vt. samas: Eesti Korteriühistute VII Foorumi avalik pöördumine Eesti Vabariigi Valitsuse, Eesti Vabariigi Riigikogu, Eesti Vabariigi Presidendi poole lk. 9, 39

  18. INTERNATIONALIZATION OF SMEs – CASE IN REPUBLIC OF MACEDONIA

    Directory of Open Access Journals (Sweden)

    ANETA RISTESKA

    2016-02-01

    Full Text Available Small and medium enterprises (SMEs are the backbone of the economy in the most of the countries around the world, their contribution can be seen in employment, export and added value. Internationalization used to be characteristic only of multinational corporations, but today it is a trend with both small and medium enterprises The main aim of this paper is to get information about the situation with internationalization of SMEs in R. Macedonia. For this purpose we carried out a survey by means of questionnaire. Obtained results are presented within this paper in details. Considering the facts from the analysis in the end of the paper we will propose many recommendations for increasing the internationalization of SMEs in Republic of Macedonia.

  19. Internationalization in German Academic Libraries: Moving beyond North American Perspectives

    Science.gov (United States)

    Bordonaro, Karen; Rauchmann, Sabine

    2015-01-01

    This paper explores how internationalization is understood and experienced in German academic libraries. Its main purpose is to move the discussion of internationalization in academic libraries beyond the boundaries of English-speaking North America by investigating a European perspective. Its secondary purpose is to investigate the role of…

  20. Internationalization of enterprises: theoretical perspectives and research agenda

    Directory of Open Access Journals (Sweden)

    Eda Castro Lucas de Souza

    2012-07-01

    Full Text Available DOI: http://dx.doi.org/10.5007/2175-8077.2012v14n33p103 The purpose of this essay is to identifythe scientific literature on internationalization of companies, and to present a research agenda on the subject. In addition, this work intends to outline and to describe the theoretical perspectives that predominate in this production. Through the review of academic literature on internationalization, from January 2005 to September2011, 141articles were selected, exposing the lack of studies that promote a direct discussion about the relationship between internationalization and culture, in particular with regard to Brazilian initiatives. Through the analysis of the selected texts it was introduced a taxonomy of three theoretical perspectives: economic, behavioral and cultural. Supported by the discussion in the published articles, a research agenda is proposed, compiled from the shortcomings pointed out in the state of art of studies on this phenomenon.

  1. Internationalization strategy of a service firm: live forum TV in Hong Kong

    OpenAIRE

    Meiners, Olivia; Khan, Aftab

    2016-01-01

    Throughout the age of globalization, the internationalization of business and entities grows importance. When considering a mode of internationalization, various different factors come into play that effect how to create a strategy for entering a new market. Regardless of cultures merging to a new global society, each market faces its own new challenges and obstacles coming from one country into the next. When studying the literature on the internationalization of services, a standardized str...

  2. Internationalization of China's MBA Education: Failing to Walk the Talk?

    Science.gov (United States)

    Ma, Shaozhuang; Trigo, Virginia

    2011-01-01

    This article presents an overview of the internationalization of MBA education in Mainland China, exposes the main challenges this education is facing and proposes strategies to overcome them. Results reveal two main findings: 1) Chinese MBA educators show a growing interest and awareness in the internationalization of their MBA education, but…

  3. Analysis of internationalization process of IBQ Britanite under the perspective of the behavioral approach

    Directory of Open Access Journals (Sweden)

    Fábio Dal-Soto

    2013-11-01

    Full Text Available The process of internationalization of companies has proceeded in different ways and contexts. Among the models that guide and explain the moves made by companies into the international market, this study is on the behavioral perspective of internationalization theories  The main objective of this paper is to analyze, in the light of the theoretical assumptions of the behavioral approach, the process of internationalization of IBQ Britanite, leader in the Brazilian civil explosives and providing services in blasting rocks . Therefore, the study is characterized by bias qualitative study using a single case study that answers the five questions of the internationalization process: why, what, when, where and how companies internationalize their activities. The results show that the process of internationalization of the company came to advantages gained both domestically and restrictions growth. Throughout his international career, the company gradually progressed in export activities, and also for stages greater commitment to the foreign market through joint ventures and production subsidiary.

  4. Going Global? Internationalizing Australian Universities in a Time of Global Crisis.

    Science.gov (United States)

    Welch, Anthony

    2002-01-01

    Analyzes the past decade's internationalization of Australian universities against a backdrop of increasing globalization, particularly the expansion of global capitalism. Examines international student flows, faculty, and programs, assessing the relative presence of internationalization (mutuality and reciprocal cultural relations) versus…

  5. International Entrepreneurship: A Meta-Analysis on the Internationalization and Performance Relationship

    NARCIS (Netherlands)

    Schwens, Christian; Zapkau, F.B.; Bierwerth, Michael; Isidor, Rodrigo; Knight, Gary; Kabst, Rüdiger

    2018-01-01

    The article conducts a meta-analysis on the relationship between internationalization and firm performance in international entrepreneurship. Empirical evidence from 15,648 internationalizing entrepreneurial firms nested in 43 independent samples reveals a positive relationship between degree and

  6. DEVELOPMENT OF THE LEVEL INDICES SYSTEM OF UNIVERSITY INTERNATIONALIZATION

    Directory of Open Access Journals (Sweden)

    Artem R. Denisov

    2015-01-01

    Full Text Available The aim of the investigation is to show possible variants of audit in the higher educational institution while processes of internationalisation (procedures of definition of its level; to find out an estimation method of the received results in the given sphere.Methods. The methods involve comparative analysis, synthesis, range and systematization of information concerning the discussed problem.Results and scientific novelty. The necessity of universities participating in internationalization processes is proved. Existing approaches to internationalization evaluation levels are reviewed, as well as best practices for each criterion. Level indicators of considered process are proposed due to summarising the results of the given review, and also as a result of the coordination of criteria NAFSA and authors’ system of indicators: international programs supporting by a university administration, curricular changes, faculty involving into international research, faculty involving into teaching process, students participation, abroad study support, international students and teachers support. The research demonstrates that to improve the adequacy the system of indicators has to be supplemented with some indicators to evaluate the conformity of a university’s internationalization to its mission; the conformity of a university’s internationalization to the government geopolitics; extracurricular activities of students; cultural aspects of internationalization including communication with local ethnical groups; attractiongetting mechanisms for international students.Practical significance. The proposed system of indicators can be used for an estimation of high school development in internationalisation sphere, and under certain correction and improvement for efficiency definition of development of its academic divisions in the given field.

  7. Marketing strategies in the internationalization process of Brazilian franchises

    OpenAIRE

    Camargo, Maria Adriana de A. P.; Rocha, Thelma Valéria; Silva, Susana Costa e

    2016-01-01

    Purpose – This paper aimed to analyze the influence of marketing strategies on the internationalization process of Brazilian franchises. The objective was to identify the marketing strategies used by Brazilian franchises during different stages of their internationalization processes and to analyze these strategies according to the Global Marketing Strategy (GMS). Design/methodology/approach – The paper adopted a qualitative research methodology based on three case studie...

  8. Family firms, internationalization, and national competitiveness : Does family firm prevalence matter?

    NARCIS (Netherlands)

    Carney, Michael; Duran, Patricio; van Essen, M.; Shapiro, Daniel

    We revisit the question of family firms (FFs) and their capacity for internationalization, and link it to the literature on national competitiveness. We draw widely on the FF competitive advantage and internationalization literature to argue that FFs’ organizing preferences and capabilities will

  9. Commodity versus Common Good: Internationalization in Latin-American Higher Education

    Science.gov (United States)

    Leal, Marco Aurelio Navarro

    2017-01-01

    The aim of this paper is to explore the meaning of internationalization using some Latin American experiences of higher education, to identify two views of this activity and pose the need for reflection upon internationalization as a means that should correspond to pedagogical ends in the context of globalization. [For the complete Volume 15…

  10. Cultures & Languages across the Curriculum: Strengthening Intercultural Competence & Advancing Internationalization

    Science.gov (United States)

    Plough, India C.

    2016-01-01

    The role of world languages in the internationalization of college campuses in the United States (U.S.) has become a recurring theme of discussions in academic, government, and private sectors. Topics have ranged from the lack of a common definition of internationalization to a review of college curricula. Klee (2009) and Bettencourt (2011) have…

  11. Auto industry late followers knowledge creation through internationalization

    Directory of Open Access Journals (Sweden)

    Marković Dušan

    2016-01-01

    Full Text Available Radical changes of business environment have been caused by growing globalization at the beginning of the 21st century. Consequently, a strong network of trade and investment relationships between national economies has been established. Although it entails many risks, global business environment opens up great opportunities, as well. In order to seize these opportunities, many companies from emerging markets internationalize their business operations, and thus challenge once untouchable leaders from developed countries. Traditional theories on multinational companies cannot fully explain their motives for going abroad. Recently, the automotive industry has become a new field where the late followers from emerging markets try to challenge the leaders. This paper includes the following three case studies: Hyundai - Kia, Geely - Volvo, and Tata Motors - Jaguar Land Rover. These case studies show that although the late followers in the automotive industry use different internationalization strategies, they all perceive internationalization as a means of obtaining the lacking competencies and building up a positive reputation.

  12. Innovative Behaviour of High-Tech Internationalized Firms: Survey Results from Poland

    Directory of Open Access Journals (Sweden)

    Krzysztof Wach

    2016-09-01

    Full Text Available Objective: The aim of the article is to identify and verify the relationship between internationalization and innovativeness as well as innovative behaviour of high-tech businesses in Polish context. Research Design & Methods: A quantitative research design was employed. A survey was conducted on the sample of 263 firms operating in high-tech industries in Poland. To verify the assumed relationships statistical instruments were used, including descriptive statistics, Chi-Square test, the Kruskal-Wallis test and multivariate regression. Findings: The level of innovativeness of investigated hi-tech firms was relatively high. Results suggest that the innovativeness of a business contributes to the intensification of the internationalization process of firms operating in high-tech industries. The regression model confirms the dependence of internationalization on three innovative behaviours, such as the general evaluation of innovativeness of the firm, the pace of innovation diffusion and the number of implemented innovations. Implications & Recommendations: Polish high-tech businesses seem to be relatively well internationalized, especially in comparisons to general business population. Policy makers should continue to support innovativeness of Polish economy, but especia­lly these industries which are highly innovative. Contribution & Value Added: The research presented in the article seems to be one of the first in Poland investigating into internationalization and innovation in high-tech industries. The results are in line with the majority of empirical evidence worldwide. The preliminary link between innovation and internationalization among Polish high–tech businesses was confirmed.

  13. SME competitiveness: An internationalization strategy for Dom Pedro Hotels

    OpenAIRE

    Feldmann, Hannah Henrike

    2013-01-01

    This paper studies the internationalization process of Dom Pedro to South Brazil. The company’s strategy is critically assessed and it is argued that a professionalization of corporate strategic planning is needed regarding further internationalization. This finding combined with a regional macro environment and hotel industry scanning helps deriving success factors for an expansion to South Brazil. Building on those factors, the market is analyzed regarding the most favorable hot...

  14. Internationalization and innovation: The case of a born global from Brazil

    Directory of Open Access Journals (Sweden)

    Thaisa Carolina Zonta

    2018-01-01

    Full Text Available The significance of Born Global firms´ study is increasing due to their early internationalization aspects, innovation and economic growth; however, most of existent studies are focused on developed markets. This is the reason why this study is addressed to analyze the internationalization effects on the innovation in a Born Global firm from emerging market. We have used the literature review about innovation, internationalization and Born Global from emerging markets, also an in-depth interview with the founder and the financial/administrative coordinator of a Brazilian Born Global company that have demonstrated a proactive internationalization behavior moving to the United States. The result shows that, the internationalization to a country with stable institutions affects positively the innovation of the firm, providing the possibility of exploring resources, resulting in financial growth, superior knowledge and capabilities. This research contributes for an improved knowledge of the phenomenon in the context of emerging markets. Also, the perspective of institutions in the host country, which determines the firm´s innovation performance and finally, we explore the case of a firm from an emerging economy that moved to a developed country (South-North to develop new capabilities and maintain its strategy of innovation.

  15. INTERNATIONALIZATION STRATEGIES OF EMERGING COMPANIES: A COMPARATIVE STUDY OF BRAZILIAN CASES

    Directory of Open Access Journals (Sweden)

    Janaína Maria Bueno

    2012-01-01

    Full Text Available Over the last decade, interest has picked up as to emerging economies and their companies. This recent movement does not imply that previous theories and models are no longer applicable, however, one must analyze, in a broader comprehensive manner, a series of specific context factors and those concerning the management of this kind of company. Therefore, this paper analyzed the internationalization strategies adopted by six Brazilian companies before a set of internationalization models. A qualitative research approach was employed and in-depth interviews were conducted with corporate management level professionals. Companies were divided into three groups according to internationalization times (Group I – over ten years, Group II - between five and ten years, and Group III – under five years. Observations indicated that for Groups I and III companies the product lifecycle (Vernon, 1966 and 1979 and the eclectic paradigm (Dunning, 1980, 1988 and 2000 economic models support justifying internationalization motivations for companies’ internalization whilst the Uppsala model (Johanson and VAHLNE, 1979, 2009, at least in part explains, choice decisions concerning a few countries. As to Group II companies, the product lifecycle model is not the underlying motivation for internationalization, choices being more closely related to sector opportunities and the characteristics of both products and services.

  16. Born Again Globals and the reconfiguration of Resources in the Internationalization Process

    DEFF Research Database (Denmark)

    Servais, Per; Decker, Arnim

    perspective in depth in the context of international new ventures (INVs) and particularly toward their marketing activities, but even fewer studies has research the very same in ”born-again” globals firms (Bell et al. 2001). Internationalization is recognized as a valuable strategy for organizations’ growth......Internationalization has become an issue in most small and medium sized enterprises (SMEs), and literature has emphasized the role of strategic choices focusing on several aspects, such as motivations, entry mode choices, internationalization process. Few studies have examined the social capital...... pathways taken by the family firm are identified eg. the level of commitment toward internationalization, the resources available, and the ability to commit and use those resources to develop the required capabilities. Furthermore, how the owner makes international decisions is explored and four...

  17. An Integrative Model of Internationalization Strategies

    DEFF Research Database (Denmark)

    Li, Xin; Gammelgaard, Jens

    2014-01-01

    – The OLI and the UIP models fail to include corporate entrepreneurship and managerial psychology in their analyses. We suggest that regulatory focus theory unifies the managerial strategic choice between position logic and opportunity logic. In addition, host country institutions affect this managerial......Purpose – This paper aims to critically review the ownership, location and internalization (OLI) model and the Uppsala internationalization process (UIP) framework. We suggest that the inclusion of concepts such as corporate entrepreneurship, host country institutions and regulatory focus...... in an integrated framework helps to explain firm internationalization. Design/methodology/approach – This paper is based on a review of the literature on the OLI and UIP models. In addition, it presents a conceptual model that encompasses corporate entrepreneurship, regulatory focus and institutions. Findings...

  18. Does internationalization foster firm performance?

    NARCIS (Netherlands)

    van den Berg, Marcel

    2014-01-01

    The research in this dissertation concerns the impact of internationalization of business activities on several dimensions of firm performance. We show that the productivity ranking by trade status of Dutch manufacturing firms in increasing order of productivity is: non-traders, importers, exporters

  19. Strategic Planning: An Examination of the Role of Disciplines in Sustaining Internationalization of the University

    Science.gov (United States)

    Agnew, Melanie

    2013-01-01

    Internationalization of the curriculum is arguably a key strategy to developing and sustaining campus-wide internationalization. Using Becher and Trowler's (2001) categorization of the disciplines, this qualitative study examined how 37 faculty members situate internationalization in the context of the disciplines. Disciplinary knowledge is viewed…

  20. Using Social Media to Accelerate the Internationalization of Startups from Inception

    Directory of Open Access Journals (Sweden)

    Tony Maltby

    2012-10-01

    Full Text Available A set of principles, processes, and tools that entrepreneurs can use to rapidly internationalize their technology startups from inception does not exist. This article discusses entrepreneurs’ use of online social media networks to rapidly internationalize their startups from inception. The article was inspired by how the founders of Dewak S.A. rapidly internationalized their technology startup. Dewak was founded by five unemployed Colombians in June 2008. Two years later, foreign sales comprised 95% of the firm’s revenue and provided the founders with full-time employment. Dewak’s only channel to market was via online social media networks. Recognizing that entrepreneurs can use social media to amplify their tacit knowledge and convert it into sellable products and services contributes to the development of a learning-based view of rapid internationalization from inception. The article provides entrepreneurs seeking to launch and grow global businesses with four recommendations that may save them time and money and increase the size of their addressable markets.

  1. Factors Affecting Internationalization of Indonesia Franchise Companies

    Directory of Open Access Journals (Sweden)

    Erwin Halim

    2013-05-01

    Full Text Available Franchise is one of successful business strategies in business expansion. Franchise format has been already adopted in all countries. The success is proven in the world and also in Indonesia. Franchise system can be implemented not only in franchisor country but also in other countries. The spirit of internalization is not only because of market saturated, but also to increase reputation of franchise companies and to follow competitors or customers. Important thing discussed in this research is the franchise life-cycle, franchise growth model, and franchise companies’ profile.  It is found that the Indonesia franchise companies are in the introduction stage. The stage in life-cycle shows its reputation. This study used literature review as methodology, and the purpose of this study is to give a big picture for Indonesia franchise companies to make internationalization. There are some Indonesia franchise business profiles in the discussion part. The factors affecting franchise internationalization were analyzed by PESTEL analysis. Some strategies should be prepared in making decision to go international.  At the end, there are some recommendations and future research relating to internationalize franchise business.

  2. Impact of EU on the internationalization of Czech SMEs in ICT industry

    OpenAIRE

    Žalman, Jakub

    2015-01-01

    ŽALMAN, Jakub. Impact of EU on the internationalization of Czech SMEs in ICT in-dustry. Diploma thesis. Mendel University in Brno, 2015. The topic of this diploma thesis is how is the fact that Czech Republic is member of the EU influencing internationalization of Czech SMEs operating in ICT industry. EU has opened and unified the internal market a lot which gave new possibilities of internationalization for member countries. Importance of the topic is also given by the facts that small and m...

  3. INTERNATIONALIZATION STRATEGIES: A CASE STUDY AT SMALL EXPORT COMPANIES

    OpenAIRE

    Elaine Di Diego Antunes; Joysinett Moraes Silva

    2009-01-01

    The purpose of this study is to identify the main internationalization strategies used by small manufacturers of hammocks. Our findings show that these export companies have up to 20 employees and their main internationalization strategy is exportation. This plan is carried out in 3 ways: indirect exportation, through trading companies; direct exportation, through sales performed in the companies and cooperative exportation, through a network of dealers in greater companies. Its was also veri...

  4. Internationalization of Peruvian cuisine: An analysis of internationalization strategies of Peruvian restaurants

    Directory of Open Access Journals (Sweden)

    Ronald M. Rivas

    2011-03-01

    Full Text Available We study the multinationalization—the decision to establish foreign direct investment (FDI—of Peruvian restaurants. Despite a long exporting tradition, many Peruvian firms have only recently become multinational enterprises (MNEs. The analysis of eighty-two cases of Peruvian restaurants FDI in the Americas, Europe and Asia, reveals several findings. First, it confirms the received view that Multilatinas take a long time to become MNEs, and they become MNEs after changes in the home country that follow structural reform induce them to upgrade their competitiveness to international levels. However, unlike previous studies, we found that Peruvian restaurants expand to countries with proximate as well as with distant psychic distance. These findings are at odds with the gradual internationalization model and the eclectic paradigm. Second, this study found support for the institutional proposition of internationalization, that is, institutional pro-market reforms benefit domestic firms over foreign MNEs, which facilitate domestic firms’ multinationalization. Peru has seen a significant economic recovery during the last decade, which just recently has created opportunities for the emergence of Peruvian Multilatinas. Third, this study found support for the RBV proposition of multinationalization namely, that unique business level strategies have different multinationalization processes.

  5. Internationalization and Corporate Cash Holdings: Evidence from Brazil and Mexico

    Directory of Open Access Journals (Sweden)

    Newton Arata

    2015-05-01

    Full Text Available This research expands on previous studies of cash holdings and their determinants by studying the relationship between the degree of internationalization and the level of corporate cash holdings. We used a sample of nonfinancial, publicly traded companies from Brazil and Mexico for the period from 2006 to 2010. Our results suggest that the degree of internationalization is a determinant of cash, and that cash holding increases quadratically as the degree of company internationalization grows. Such behavior was different from the North American company studies in Chiang and Wang (2011. Similar to previous studies, both Trade-off and Pecking Order predictions are relevant control variables in our model. Finally, companies held less cash on their balance sheets during the precrisis period.

  6. INTERNATIONALIZATION OF SMES - A SOLUTION TO OVERCOME THE CURRENT ECONOMIC CRISIS

    Directory of Open Access Journals (Sweden)

    Corina Ana BORCOŞI

    2010-12-01

    Full Text Available There is a close link between economic performance and increasing internationalization of SMEs. International activities increase competitiveness and ensure long-term development of enterprises. However, European SMEs still depend largely on their internal markets, notwithstanding the opportunities created to the single market and globalization in general. A study realized in 2009 by the European Commission reveals that internationalization creates more jobs: SMEs active in foreign markets reported an increase in employment by 7% compared to only 1% free activities for SMEs international. Internationalized SMEs are more innovative: 26% of SMEs have introduced internationally active products or services that were new to the sector in their country of origin.

  7. A Model for Stakeholders' Influence on Internationalization: A Contribution from the Portuguese, Brazilian, and Dutch Cases

    Science.gov (United States)

    Castro, Rita; Rosa, Maria João; Pinho, Carlos

    2015-01-01

    This article aims to discuss stakeholders' influence on higher education institutions' (HEIs) internationalization, through an analysis of the relationships established between stakeholders' importance and the institutions' rationales for internationalization, the strategies developed for internationalization, and the benefits from…

  8. Internationalization of Higher Education and the Impacts on Academic Faculty Members

    Science.gov (United States)

    Bedenlier, Svenja; Zawacki-Richter, Olaf

    2015-01-01

    Research on internationalization processes in higher education has steadily increased over the past decades. However, there is still a lack of analysis of how these developments have affected higher education and, specifically, the group of academic faculty members. To close this gap, this study explores the effects of internationalization on this…

  9. Internationalization of Oman Fisheries Firms After the European Union Ban

    Directory of Open Access Journals (Sweden)

    L. Zaibet

    2004-06-01

    Full Text Available This paper examines the impacts of the l998 ban on Oman fish exports to the EU markets and ensuing the internationalization of Oman fish companies. The ban raises two concerns that the paper intends to answer: (i how firms have responded to surmount the ban, and (ii which strategies are more effective in the process of internationalization. The paper distinguishes three sets of actions: during the ban and immediate actions; short term actions; and long term actions. Besides government support for the implementation of international norms of quality and safety control, firms have responded individually to the EU ban. The actions subsequently undertaken by firms in response to the ban were selected: identification of new markets (alternatives; implementation of the required regulations and needed support to continue exporting to traditional European markets (competence; and long term business and marketing strategies (strategic thinking. These actions or steps represent the internationalization process or approach followed by the fisheries firms in Oman. All these actions have been undertaken after the EU ban, which leads to the conclusion that the ban has indeed worked as a driving force to internationalize, i.e. to develop the requisites of international markets.

  10. Rapid internationalization and long-term performance: The knowledge link

    OpenAIRE

    García-García, Raquel; García-Canal, Esteban; Guillén, Mauro F.

    2017-01-01

    Drawing on the knowledge-based view and organizational learning theory, we develop and test a set of hypotheses to provide a first attempt at analyzing the effect of speed of internationalization on long-term performance. Using a panel-data sample of Spanish listed firms (1986-2010), we find that there is an inverted U-shaped relationship between speed of internationalization and long-term performance. We also find that whereas technological knowledge steepens this relationship, the diversity...

  11. Internationalization of IKEA in the Japanese and Chinese markets.

    OpenAIRE

    Cheancharadpong, Wanee; Chaletanone, Wannapa

    2008-01-01

    Date: June 4, 2008 Level: Master Thesis EFO705, 10 points (15 credits) Authors: Wannapa Chaletanone (05-11-1982, Thailand) Wanee Cheancharadpong (03-09-1983, Thailand) Title: Internationalization of IKEA in the Japanese and Chinese markets Supervisor: Leif Linnskog Problems: Why did IKEA internationalize into Japanese and Chinese markets? And what factors did influence IKEA’s success in Chinese market but failure in the Japanese market of the first round? Purpose: The aim of thesis is to unde...

  12. Emerging Market Multinational Companies and Internationalization

    DEFF Research Database (Denmark)

    Nielsen, Bo Bernhard; Estrin, Saul; Nielsen, Sabina

    2014-01-01

    This paper furthers our understanding of the role of contextual conditions influencing internationalization of emerging market multinational companies (EMNCs). We use resource-based, industrial organization, and economic development theories to develop a multilevel theoretical framework...

  13. Prospects for the Development and Internationalization of Higher Education in Asia

    Science.gov (United States)

    Krechetnikov, Konstantin; Pestereva, Nina; Rajovic, Goran

    2016-01-01

    This study investigates the current process of internationalization of higher education in the countries of the Asia Pacific region (APR) through the example of China, the Republic of Korea, Japan, and Russia. The article aims to familiarize the reader with the experience of internationalizing higher education in APR states against a backdrop of…

  14. Cultural Distance and Firm Internationalization : A Meta-Analytical Review and Theoretical Implications

    NARCIS (Netherlands)

    Beugelsdijk, Sjoerd; Kostova, Tatiana; van Essen, M.; Kunst, Vincent; Spadafora, E.

    This paper presents the most comprehensive review and meta-analysis of the literature on cultural distance and firm internationalization to date. We analyze the effects of cultural distance on key strategic decisions throughout the entire process of internationalization. For the preinvestment stage,

  15. The Effects of Internationalization on Innovation: Firm-Level Evidence for Transition Economies

    NARCIS (Netherlands)

    Martijn Boermans; Hein Roelfsema

    2012-01-01

    It is well-documented that international enterprises are more productive. Only few studies have explored the effect of internationalization on productivity and innovation at the firm-level. Using propensity score matching we analyze the causal effects of internationalization on innovation in 10

  16. ENDF/B-VII.1 versus ENDF/B-VII.0: What's Different?

    International Nuclear Information System (INIS)

    Cullen, D.E.

    2012-01-01

    Recently the new ENDF/B-VII.1 library was released; this completely replaces the earlier ENDF/B-VII.0 library. One of the first questions we ask about a new library is: What's Different? Here I attempt to at least partially answer this question. I present results in both tabulated form (so you can quickly determine if any evaluations of interest to you have changed), and graphic form (so that you can see how much evaluations have changed and in what energy ranges). For the table I have compared what I refer to as the ENDF neutron data, namely MF=1 through 6. Here I did a character-by-character comparison of the same sections (MF/MT) that appear I both ENDF/B-VII.0 and VII.1; here I found differences in 170 evaluations. For the plots I have only compared the total cross sections for all evaluations that are common to both libraries, and I found that of the 423 evaluations in ENDF/B-VII.1, 120 of these have total cross sections that differ by 1% or more from the evaluation of the same isotope in ENDF/B-VII.0. This should be considered only a preliminary comparison; obviously there can be more subtle important differences that do not effect of total cross sections. Here I present plots comparing the total cross section of these 120 isotopes. The plots are only broad overviews of the total cross sections over their entire energy range. If you have interest in more detailed plots for specific evaluations, you can download the evaluations (1,2) and the PREPRO (3) codes I used to prepare and view the data. This is all I needed to do my comparisons, and is all you should need to do any more detailed comparisons to meet your individual needs.

  17. An Analysis on localization and Internationalization of Universities Curriculum in the Globalization Era

    Directory of Open Access Journals (Sweden)

    Ali Ghasempoor

    2011-12-01

    Full Text Available In recent years, the subject of internationalization has been one of the most discussed issues in academic centers. Higher education experts' beliefs that this subject is a new paradigm and inevitable approach in curriculum development of universities. Internationalization is a term that refers to the process of integrating an international and intercultural dimension into the teaching, research and service functions of the institution. Localization is another approach that refers to promotion, adaptation and development of knowledge, technology, culture and specific values in the specific context and alike internationalization is a response to globalization. The purpose of this study is, surveying the nature of internationalization and its causality, practical models and principals and specifying its relation to multiple theories of fostering local knowledge and localization in globalization of education context. These theories have varied emphasis on global dependence and local orientation and therefore they have their own characteristics, strengths, and limitations in conceptualizing and managing the process of fostering local knowledge and human development. Clearly, their implications for design of curriculum and instruction and their expected educational outcomes in internationalization of curriculum are correspondingly different. Each country or local community may have its unique social, economic and cultural contexts and therefore, its tendency to use one theory or a combination of theories from the typology in globalizing and internationalizing education may be different from that of others.

  18. Internationalization and technological catching up of emerging multinationals: a comparative case study of China's Haier group

    OpenAIRE

    Geert Duysters; Jojo Jacob; Charmianne Lemmens; Yu Jintian

    2009-01-01

    A number of firms from China and India have in recent years been demonstrating their ability to face up to the challenges of globalization by internationalizing their operations. In this article we carry out a case study of China's Haier Group followed by a comparison of its growth and internationalization with those of India's Tata Group. We examine several aspects of their internationalization, such as the mode of internationalization and the choice of overseas destinations. The study furth...

  19. INTERNATIONALIZATION OF EDUCATION ON THE EXAMPLE OF KRASNOYARSK STATE AGRARIAN UNIVERSITY

    Directory of Open Access Journals (Sweden)

    Natalia Vladimirovna Antonova

    2018-04-01

    Full Text Available Purpose. The article is devoted to issues of internationalization of educational process in Federal state budget educational institution of higher education “Krasnoyarsk State Agrarian University”. The authors’ aim is to analyze and describe the methodology for this work at Krasnoyarsk State Agrarian University. Methods. Theoretical and empirical methods of research, such as analysis and synthesis of the information available in psychological and pedagogical literature, as well as modelling, observation and experiment constitute the basis of the research. Results. In the study, the authors analyze and substantiate the reasonability of the implementation of practical forms of education internationalization at Krasnoyarsk State Agrarian University, as the basis for fulfillment of the efficiency indicators in the higher education institutions monitoring, including internationalization of curricula and educational programs, mobility of students and teachers, as well as the export of educational services as a separate component of the internationalization. Separately, the linguistic and socio-psychological adaptation of foreign students in Krasnoyarsk State Agrarian University as the basis of internationalization is examined. The work on the internationalization of education in the Krasnoyarsk State Agrarian University allowed fulfilling the indicator of monitoring. If in 2014 the university had only 0,41% of foreign students in the given contingent, then starting with 2015, the indicator is met. In 2017, it was 4,8%. The indicator of the receipt of funds from foreign students training also increased from 1,8 million rubles in 2016, up to 2,2 million rubles in 2017. Practical implication and results. The results of the study may be of interest for the management of higher educational institutions implementing the provisions of the Bologna Declaration, the staff of the international and educational departments of universities and can be used as

  20. Being an Educator in a Foreign Environment: One Road to becoming Internationalized

    Science.gov (United States)

    Albaum, Gerald

    2011-01-01

    What does "internationalizing" university educators mean? This question is being answered differently by business schools everywhere. Although business schools are seeking to internationalize themselves, many are doing so without fully understanding what this might entail. One dimension that often is misdirected is the individual…

  1. Internationalization Management in Japanese Universities: The Effects of Institutional Structures and Cultures

    Science.gov (United States)

    Yonezawa, Yukako

    2017-01-01

    This study examines approaches to the internationalization of Japanese universities by focusing on the effects of institutional structures and cultures. Using a qualitative case study method, the research examines the following question: "How do institutional structures and cultures affect the internationalization of education in Japanese…

  2. Emerging Market Multinational Companies and Internationalization

    DEFF Research Database (Denmark)

    Estrin, Saul; Nielsen, Bo B.; Nielsen, Sabina

    2017-01-01

    We develop a multilevel theoretical framework for investigating the role of home country urbanization for emerging market multinational companies' (EMNCs) international expansion. We propose that more urbanized home environments directly increase EMNC's proclivity to internationalize and moderate...

  3. Global Players from Brazil: drivers and challenges in the internationalization process of Brazilian firms

    OpenAIRE

    Carvalho, Flavia; Costa, Ionara; Duysters, Geert

    2010-01-01

    This chapter discusses general patterns of internationalization of Brazilian firms. It highlights the main determinants for internationalization, the main destinations, as well as the modes of entry that Brazilian firms employ overseas. The paper also discusses some aspects related to the technological capabilities of Brazilian firms that are related to their internationalization strategies, in terms of both the exploitation of such advantages and the search for technological assets abroad.

  4. Genetics Home Reference: factor VII deficiency

    Science.gov (United States)

    ... Facebook Twitter Home Health Conditions Factor VII deficiency Factor VII deficiency Printable PDF Open All Close All Enable Javascript to view the expand/collapse boxes. Description Factor VII deficiency is a rare bleeding disorder that varies ...

  5. Innovation and Internationalization of Hungarian SMEs in the IT Industry

    Directory of Open Access Journals (Sweden)

    Csonka László

    2014-10-01

    Full Text Available The aim of this paper is to look at the extent and type of internationalization among Hungarian information technology (IT small- and medium-sized enterprises (SMEs and the possible relationship between the degree of innovativeness and the internationalization of these companies. Information technologies play an important role in the Hungarian economy: this sector is one of the most R&D intensive industries in which many SMEs are active.

  6. An empirical examination of the influence of industry and firm drivers on the rate of internationalization by firms

    Science.gov (United States)

    Elango, B.

    A gradual shift in U.S. firms' 'center of gravity' toward international markets is taking place. This study seeks to explain which drivers are related to this push toward international markets by U.S. firms. In addressing internationalization, previous research has not focused on various drivers that influence the rate of internationalization. Drivers refer to forces, both within and outside the firm, that impact (both positively and negatively) a firm's extent of internationalization. The role of these drivers on the rate of internationalization, though acknowledged in the literature, is yet to be validated through empirical research. This research seeks to narrow the gap in the literature by testing the various relationships among industry drivers, firm drivers, and the rate of internationalization. The objectives of this study are: (A) To develop a conceptual framework that takes into account various forces that influence the internationalization strategy of a firm; (B) To examine empirically (a) the influence of industry drivers on the rate of internationalization pursued by firms; and, (b) the influence of firm drivers on the rate of internationalization by firms. The sample for this study consists of 158 large U.S.- based multinational firms drawn from seven different industries. Data for the study is gathered from a variety of sources including the U.S. Department of Commerce, Bureau of Economic Analysis; COMPUSTAT; and WORLDSCOPE databases. Set-wise regression models were used for data analysis. This study found that global market growth rate, domestic market growth rate, relative size of domestic market to international market, employee productivity, administrative investments, as well as new plant and equipment influences the international strategy of firms. This study explains about 24 percent of the variance of the rate of internationalization. This research finding is contributory to our existing understanding of internationalization in many ways

  7. Internationalization of Canadian Higher Education: Discrepancies between Policies and International Student Experiences

    Science.gov (United States)

    Guo, Yan; Guo, Shibao

    2017-01-01

    The internationalization of higher education in Canada is happening at a rapid pace. One manifestation of internationalization is the increasing enrolment of international students in Canadian institutions. There is little research on international undergraduate students' experiences from their own perspectives as they adapt to a new educational…

  8. Internationalization Strategies for the Global Knowledge Society. CBIE PhD Research Series

    Science.gov (United States)

    Szyszlo, Peter

    2016-01-01

    The purpose of this article is to improve understanding of internationalization as a strategic response to the catalysts of globalization and the knowledge society. The paper will attempt to critically identify and interpret how the aforementioned elements are being recontextualized and translated into responsive internationalization policies and…

  9. On Significance of Cross-cultural Communication in International Business-Specified on Accounting Internationalization

    Institute of Scientific and Technical Information of China (English)

    刘洁

    2011-01-01

    There is limited information about intercultural communication during the process of accounting internationalization,and Chinese accounting still has a long way to go because of the disparity in accounting principles,business culture and so on.This paper talks about the necessity of accounting internationalization and the importance of intercultural communication skill,aiming at reminding people that a good command of intercultural communication skill is a must.Some suggestions are given in hope of contributing to cross-cultural communication during the process of Chinese accounting internationalization.

  10. Internationalization through business model innovation: In search of relevant design dimensions and elements

    DEFF Research Database (Denmark)

    Rask, Morten

    2014-01-01

    Internationalization through business model innovation involves the creation, or reinvention, of the business itself. This paper aims to integrate basic insight from the literature on business model innovation, internationalization of the firm, international entrepreneurship and global marketing...

  11. Small Firm Internationalization, Innovation, and Growth

    NARCIS (Netherlands)

    Boermans, M.A.; Roelfsema, H.J.

    2016-01-01

    This paper studies the effect of internationalization on innovation and firm performance (employment growth and sales growth) taking the interdependencies among the variables into account. Given the potential endogeneity, this study uses theory-driven instrumental variables and structural equation

  12. Institutional Distance and the Internationalization Process

    DEFF Research Database (Denmark)

    Pogrebnyakov, Nicolai; Maitland, Carleen

    2011-01-01

    This paper applies the institutional lens to the internationalization process model. It updates the concept of psychic distance in the model with a recently developed, theoretically grounded construct of institutional distance. Institutions are considered simultaneously at the national and industry...

  13. Paris INDCs: will they achieve the goal of the Paris Climate Agreement?

    Science.gov (United States)

    Tribett, W. R.; Salawitch, R. J.; Hope, A. P.; Bennett, B.; Canty, T. P.

    2016-12-01

    We provide an overview of the Intended Nationally Determined Contributions (INDCs) submitted prior to the 21st meeting of the Conference of the Parties to the United Nations Framework Convention on Climate Change, which are the backbone of the Paris Climate Agreement. Two flavors of INDCs were submitted: unconditional (i.e., firm commitments) and conditional (commitments contingent on financial flow and/or technology transfer). Generally, the Paris INDCs extend to year 2030. However, achievement of either the target (1.5 °C warming) or upper limit (2.0 °C warming) of the Paris Agreement requires consideration of emissions out to 2060, due to the projected rise in energy demand, growing populations, and rising standards of living. We therefore project global carbon emissions out to year 2060, and compare to various RCP scenarios of IPCC (2013). These projections will be used to assess whether the target (1.5 °C warming) or upper limit (2.0 °) of the Paris Climate Agreement will be met.

  14. Instant Internationalization of Emerging Economy New Ventures

    DEFF Research Database (Denmark)

    Turcan, Romeo V.

    2012-01-01

    Being positioned and the intersection of international entrepreneurship and institutional theory, this study explores the process of instant internationalization of new ventures from emerging economies. It adopts a single-case study methodology, purposefully selecting an information-rich case where...... context of an emerging industry. Yet another set of contributions concerns the legitimation process of internationalization of a new venture from an emerging economy. A number of propositions are put forward to guide future research....... the phenomenon is manifested intensely, but not extremely. A family-owned venture located in Moldova that is in the business of processing fruit and vegetables was selected for this study. It started up in 2000 and from its inception the sales from exports grew almost 120% per year. Data collection took place...

  15. The Internationalization Process of the E-marketplace Ex-Trade

    DEFF Research Database (Denmark)

    Rask, Morten

    This case describes the internationalization process and the considerations about a future international expansion of a very successful e-marketplace. The case illustrates the complexity of internationalizing an internet-based SME. Ex-Trade has identified the most suitable entry modes; i.e. entry...... modes that can handle a fast, broad and deep international expansion process with very limited resources. The case raises important questions as to the importance of physical presence for a dot.com firm selling digital products; products that in theory can be distributed digitally but in practice need...

  16. Internationalization process of h3 to the German market

    OpenAIRE

    Correia, Mariana Assis Teixeira Neiva

    2012-01-01

    A Work Project, presented as part of the requirements for the Award of a Masters Degree in Management from the NOVA – School of Business and Economics The goal of this thesis is to make an internationalization plan of h3 to the German Market. h3 is a Portuguese fast-food restaurant chain mainly placed in the food courts of shopping centers serving a variety of menus with a mono-product, an hamburger. h3 has started the internationalization process in 2011 being now present in Spain, Poland...

  17. SWOT analysis and revelation in traditional Chinese medicine internationalization.

    Science.gov (United States)

    Tang, Haitao; Huang, Wenlong; Ma, Jimei; Liu, Li

    2018-01-01

    Traditional Chinese medicine (TCM) is currently the best-preserved and most influential traditional medical system with the largest number of users worldwide. In recent years, the trend of TCM adoption has increased greatly, but the process of TCM internationalization has suffered from a series of setbacks for both internal and external reasons. Thus, the process of TCM internationalization faces formidable challenges, although it also has favourable opportunities. Using SWOT analysis, this paper investigates the strengths, weaknesses, opportunities and threats for TCM. These findings can serve as references for TCM enterprises with global ambitions.

  18. An Integrative Model of Internationalization Strategies

    DEFF Research Database (Denmark)

    Li, Xin; Gammelgaard, Jens

    2012-01-01

    This paper critically reviews the ownership, location, and internalization (OLI) model, and the Uppsala internationalization process (UIP) framework. Both the OLI model and the UIP model ignore to incorporate the insights of each other and fail to include corporate entrepreneurship in their analy...

  19. Expansion patterns of Dutch firms in Central and Eastern Europe : Learning to internationalize

    NARCIS (Netherlands)

    Drogendijk, H.J.

    2001-01-01

    In this study, the internationalization decisions of firms are looked at from a dynamic perspective. Internationalizing firms gradually build the experience that help them to reduce uncertainty and expand further into new international markets. Earlier experiences are seen as stepping stones that

  20. Increased volume of distribution for recombinant activated factor VII and longer plasma-derived factor VII half-life may explain their long lasting prophylactic effect.

    Science.gov (United States)

    Mathijssen, Natascha C J; Masereeuw, Rosalinde; Holme, Pal Andre; van Kraaij, Marian G J; Laros-van Gorkom, Britta A P; Peyvandi, Flora; van Heerde, Waander L

    2013-08-01

    Prophylaxis with plasma-derived or recombinant activated factor VII is beneficial in severe factor VII deficiency. To understand why prophylactic treatment with both products is efficacious, we conducted a pharmacokinetic study. Ten factor VII deficient patients were treated with either recombinant activated (20 μg/kg) or plasma-derived (25 IU/kg) factor VII in a cross-over design. Pharmacokinetic parameters were analyzed through activated factor VII activity, factor VII clotting activity, and factor VII antigen levels on depicted time points. Factor VII activity half-lifes, determined by non-compartmental and one-compartmental analysis (results in brackets), were shorter for recombinant activated (1.4h; 0.7h) than for plasma-derived factor VII (6.8h; 3.2h); both recombinant activated (5.1h; 2.1h and plasma-derived factor VII (5.8h; 3.2h) resulted in longer half-lives of factor VII antigen. Activated factor VII half-lives (based on activated factor VII activity levels) were significantly higher compared to factor VII clotting activity (1.6h; 0.9h). Volumes of distribution were significantly higher for activated factor VII (236 ml/kg; 175 ml/kg, measured by activated factor VII) as compared to plasma-derived factor VII (206 ml/kg; 64 ml/kg, measured by factor FVII activity), suggesting a plasma- and extracellular fluid distribution for recombinant activated factor VII. Recombinant activated factor VII showed significantly shorter half-lifes than plasma-derived factor VII. Volumes of distribution were significantly higher for treatment with recombinant activated factor VII. The longer half-life for plasma-derived factor VII, compared to recombinant activated factor VII, and the increased volume of distribution for recombinant activated factor VII, compared to plasma-derived factor VII may further elucidate the beneficial effect of prophylactic treatment of both products. Copyright © 2013 Elsevier Ltd. All rights reserved.

  1. Bank Consolidation, Internationalization, and Conglomeration; Trends and Implications for Financial Risk

    OpenAIRE

    Gianni De Nicolo; Mary G Zephirin; Philip F. Bartholomew; Jahanara Zaman

    2003-01-01

    This paper documents global trends in bank activity, consolidation, internationalization, and financial firm conglomeration, and explores the extent to which financial firm risk and systemic risk potential in banking are related to consolidation and conglomeration. We find that while there is a substantial upward trend in conglomeration globally, consolidation and internationalization exhibit uneven patterns across world regions. Trends in consolidation and conglomeration indicate increased r...

  2. The Impacts of Internationalization on Quality Assurance Policy: A Comparative Study of Finland and Taiwan

    OpenAIRE

    LIU, PO-YUN

    2008-01-01

    Internationalization and quality assurance have become the central considerations of higher education development currently. The aim of this research is to explore and compare the impacts of internationalization on quality assurance policy in Finland and Taiwan. To achieve this aim, the general impacts of internationalization on quality assurance policy have been discussed first. Next, the empirical research of Finland and Taiwan are conducted by qualitative interviews of higher education pol...

  3. Franchising and the internationalization of businesses: the case of fast food chains

    Directory of Open Access Journals (Sweden)

    Fadil Alnassar

    2017-09-01

    Full Text Available The objective of this paper is to investigate the role of franchising in the process of internationalization of the fast food industry. The paper hypothesizes that franchising is an effective means of internationalization in the fast food industry that increases the revenues of the company. The hypothesis of the paper will be tested using the linear regression analysis. This analysis studies the relationship between revenues (dependent variable and the number of outlets and the number of employees (independent variables. The sample includes 15 fast food chains from the list of 100 top franchises of 2017. The study of the annual reports of these 15 fast food chains revealed a correlation between the company’s decision to go global through franchising and the growth of its revenues. It is necessary to build a literature on the role of franchising in the internationalization of business. The originality of this paper lies in the way it seeks to illuminate future academic research on the impact of franchising as an internationalization process on business revenues.

  4. A Cost-based Explanation of Gradual, Regional Internationalization of Multinationals on Social Networking Sites

    DEFF Research Database (Denmark)

    Pogrebnyakov, Nicolai

    2017-01-01

    This paper examines firm internationalization on social networking sites (SNS). It systematically examines costs faced by an internationalizing firm and how firms react to these costs according to “distance-dependent” (gradual and regional) and “distance-invariant” (born-global) explanations...... of internationalization. Data on 5827 country pages of 240 multinational firms on Facebook, the most popular SNS today, is used. Creating a foreign country-specific Facebook page is considered the SNS equivalent of opening a physical subsidiary in that country. The data show that multinationals exhibit...

  5. Internationalization process of TUBOFURO

    OpenAIRE

    Carvalho, Ludovic

    2016-01-01

    The central objective of this case study was to formulate the strategy of internationalization of Tubofuro®, discriminating relevant points from its design to its implementation. This is a company located in Leiria, Ortigosa parish, which operates, among others, in the Portuguese PVC pipes industry for which currently the domestic market is clearly insufficient, given the oversupply compared to demand. Being Tubofuro® an exporting company since 2004, the work here developed specifically...

  6. Characterization of the internationalization process of the Ecuadorian PyME

    Directory of Open Access Journals (Sweden)

    Wilson Araque Jaramillo

    2016-02-01

    Full Text Available In this study that is made with a descriptive focus, we can find some instruments that help us understand the potential the internationalization of business has; which are also known as PyME –small and medium sized companies-. This work will contribute to generate key guidelines for the process of management decisions, the design of national and local public politics with questions that will motivate the developing of new research, focusing on commercial internationalization of national production.

  7. Monoclonal anti-human factor VII antibodies. Detection in plasma of a second protein antigenically and genetically related to factor VII.

    OpenAIRE

    Broze, G J; Hickman, S; Miletich, J P

    1985-01-01

    Several murine monoclonal anti-human Factor VII antibodies were produced using hybridoma technology. Two noncompetitive monoclonal antibodies were used to examine by Western blotting the Factor VII cross-reactive material (CRM) in normal human plasma and three commercially available congenitally Factor VII-deficient plasmas, and to construct a facile "sandwich" immunoassay for plasma Factor VII. A second, previously undescribed, form of Factor VII CRM was detected in human plasma, which on We...

  8. A New Typology for Analyzing the Direction of Movement in Higher Education Internationalization

    Science.gov (United States)

    Wu, Hantian; Zha, Qiang

    2018-01-01

    This article proposes a new typology of "inward- and outward-oriented" higher education (HE) internationalization based on the spread of innovations that involve knowledge, culture, HE models, and norms. It reviews existing typologies related to HE internationalization; discusses theories of world system, soft power, and knowledge…

  9. Discovering Gaps in Internationalization Competences of SMEs¨Ca Comparative Case Study of Austrian SMEs

    OpenAIRE

    Johanna Anzengruber

    2015-01-01

    This article adds to the debate on internationalization competences of SMEs. After an examination of the most influential papers, we systematically discuss the role of individual and organizational competence gaps before and during the internationalization phase. In more detail, we raise the question what kinds of competences gaps hinder SMEs to go international and what competence gaps arise during the internationalization. This is done using a comparative case study design with competence g...

  10. Internationalizing Services : Market research on exporting Finnish educational solutions to Nigeria

    OpenAIRE

    Asemokha, Agnes

    2012-01-01

    This thesis is aimed to bring clarity to the concept of internationalization and service (education) exports as an International Business tool. The study is commissioned by Finpros’ (The Finnish export organization) Future Learning Finland project an umbrella programme whose objective is internationalizing and exporting Finnish educational solutions to other countries. The commissioning party aims to use the study in its marketing activities. Therefore, this paper is built based on a hypothet...

  11. Organizational Culture and Firms’ Internationalization, Innovativeness and Networking Behaviour: Hofstede Approach

    OpenAIRE

    Maja Szymura-Tyc; Michał Kucia

    2016-01-01

    Objective: The objective of this paper is to describe the features of firms’ organizational culture within four of Hofstede’s national culture dimensions and their potential relationships with internationalization, innovativeness and networking behaviour of firms. Research Design & Methods: This explorative quantitative research refers to results of an earlier study on internationalization, innovativeness and networking of firms in Poland. Descriptive statistics are used to depict the...

  12. INTERNATIONALIZATION STRATEGIES: A CASE STUDY AT SMALL EXPORT COMPANIES

    Directory of Open Access Journals (Sweden)

    Elaine Di Diego Antunes

    2009-04-01

    Full Text Available The purpose of this study is to identify the main internationalization strategies used by small manufacturers of hammocks. Our findings show that these export companies have up to 20 employees and their main internationalization strategy is exportation. This plan is carried out in 3 ways: indirect exportation, through trading companies; direct exportation, through sales performed in the companies and cooperative exportation, through a network of dealers in greater companies. Its was also verified that some organizations export up to 60% of their products while the vast majority does not even export 5% of it, turning primarily to the domestic market.

  13. The Internationalization Process of Mature Danish Small and Medium-Sized Enterprises

    DEFF Research Database (Denmark)

    Myhre, Malene

    that the decision to internationalize is often determined by opportunity. In many cases, the choice of a particular market is not a deliberate strategy but the result of an unplanned chance opportunity. Furthermore, the findings reveal that most SMEs have a preference for near markets and that the motivation...... of what makes mature enterprises which have predominantly had a domestic orientation decide to internationalize. Through ten case studies in three industries – machinery manufacturing, food distribution, and healthcare – this study qualitatively explores the internationalization process of mature SMEs...... with respect to pre-entry market research, market (choice) and entry mode. Through a number of semi-structured, in-depth interviews, I examine (a) how SMEs select their market; (b) how they conduct market research, and (c) how they choose their entry mode. The analysis shows two main reasons...

  14. Effects of Internationalization on Innovation in the Service Industry: Evidence from Korea

    Directory of Open Access Journals (Sweden)

    Jaeho Lee

    2014-12-01

    Full Text Available This paper examines the impact of internationalization on the product, process and organizational innovations of Korean service firms. Despite the increasing importance of the service sector and the discrepancies in the natures of the manufacturing and service industries, the internationalization-innovation link in the context of service firms has rarely been examined empirically on a large sample. Based on the results of the logistic regressions using the 2006 Korean Innovation Survey data, we found that Korean service firms' international expansion is significantly and positively associated with their product and organizational innovations. In addition, the magnitude of the estimates in our models revealed that internationalization has a greater impact on product innovation than on process or organizational innovation.

  15. The Specifics of the Internationalization Process of Czech SMEs in the Food Industry

    Directory of Open Access Journals (Sweden)

    Marcela Tuzová

    2017-01-01

    Full Text Available The aim of this paper is to define the specifics of the internationalization process of Czech small and medium-sized enterprises (SMEs in the food industry. The food industry is the largest manufacturing sector in the EU which consists mainly of SMEs. However, in the Czech Republic it has to face increasing imports of foreign food products because of growing globalization, while exports lag behind. Thus, enterprises should be encouraged to internationalize in a greater extent to maintain their competitiveness. The paper explores the main motives, barriers and risks involved in internationalization as perceived by these enterprises. The results are based on primary data obtained by questionnaire surveys performed among Czech food industry SMEs, thus it is based on data about SME’s real experiences and perception of interntaionalization process. According to our results, Czech SMEs from food industry are driven to internationalize mainly by their efforts to grow or by unsolicited foreign demand for their product. However, as the biggest barriers are perceived those connected with the lack of knowledge about foreign market and administrative requirements. The identified motives and barriers are compared with results of similar researches from Slovakia and Poland. Moreover, the results of Czech SMEs risk perception in internationalization are depicted in risk matrix which assess not only the effect of risk but also the possibility of its occurrence.

  16. THE INTERNATIONALIZATION OF SMES. A SYNTHETIC ANALYSIS OF THE DECISIONAL FACTORS AND PROCESS

    Directory of Open Access Journals (Sweden)

    Livia Oltean

    2013-06-01

    Full Text Available Having an increased complexity, the internationalization process of small and medium- sized enterprises (SMEs becomes, in the context of globalization and of the freedom of circulation of goods, services, and capital, a decisive factor of both the evolution of the company and the economic force distribution report on the market. The evolution of the world economic system opened a wide action field for small and medium sized companies, who had to adapt to new rules. The internationalization of SMEs is no longer an option, but it becomes a condition of their existence. A high importance in this process belongs to the way decisions are made, both regarding the target market and the entry option, the way entry barriers are overcome and the promotional techniques in this extended business environment. A synthetic analysis of the decisional factors and process is needed in order to fully and correctly understand the internationalization strategies adopted by SMEs. This paper is built around three major objectives, with the scope of determining the SMEs’ internationalization decisions, as well s the impediments met in the process. The paper contributes to the literature in the field of the internationalization of SMEs through the analysis and interpretation of the results acquired during the study regarding their behavior towards the activity expansion on international markets.

  17. Political ideologies and internationalization of family firms in emerging markets: : The Case of Chile

    NARCIS (Netherlands)

    Duran, Patricio; Kostova, T.; van Essen, M.

    This paper examines the effect of government political ideology on internationalization of family-controlled firms (FCFs). FCFs tend to internationalize less than non-FCFs, because of their loss aversion and conservative concerns about maintaining the family’s socioemotional wealth (SEW). We propose

  18. Social Capital in the Internationalization of Knowledge-Intensive new Ventures

    DEFF Research Database (Denmark)

    Madsen, Henning; Neergaard, Helle

    2005-01-01

    no international activities. Based on statistical analysis it elucidates the relationship among a number of factors related to social capital which may influence the internationalization process. These factors include the number and types of contacts as well as how these contacts are utilized. The results indicate......It has long been recognised that social capital in the shape of network relationships plays a significant role in the internationalisation process of a business. This research seeks to further the discussion of how social capital influences the early internationalization of new technology...

  19. The process of internationalization and expatriation: the case of Weg S.A in China

    Directory of Open Access Journals (Sweden)

    Janaina Mortari Schiavini

    2012-06-01

    Full Text Available This article aims to analyze the process of internationalization and expatriation of WEG Electrical Equipment S.A in China. The recent movement of internationalization of Brazilian companies is characterized by cases of multinationals such as WEG, which performs Foreign Direct Investments in search for increasing their participation in international business and gain of competitive advantage. This study has a descriptive character and qualitative nature, using the case study as research method, in which the objects of observation were the processes of internationalization and expatriation of WEG in China. First, secondary data was used aiming to characterize the decision of entry mode in China and their process of internationalization. Later, a semi-structured interview was held, whose questions attempted to understand how the process of expatriation of employees of WEG in the Chinese mission happened. The results show the challenges faced by the company with their inclusion in the Asian market, the determining aspects of the expatriation process and its relation to theoretical models. It is expected that this work contribute to generate knowledge about the internationalization of Brazilian companies and the leading of their expatriations, since those themes demand for conclusive research for clarification of the theoretical models on the Brazilian reality.

  20. The influence of formal institutions on the internationalization of companies in an emerging country

    Directory of Open Access Journals (Sweden)

    Jefferson Marlon Monticelli

    2017-07-01

    Full Text Available Purpose – The goal of this study is to use the institution-based view as the background for an investigation of how formal institutions influence the internationalization processes of firms from an emerging economy. Design/methodology/approach – Our case study is based on semistructured interviews with twenty-one representatives of formal institutions and firms in the Brazilian wine industry. Findings – It was noted that formal institutions have positive influences on the internationalization of Brazilian wineries by providing learning, relationship networks, intelligence about foreign markets, costs reduction, internationalization of business processes, and by promoting the home country’s image as a wine producer in foreign markets, and as a recognized supplier to the domestic market. They also have negative influences, as excessive bureaucracy, strikes, erection of legal barriers to trade with other countries, insufficient technical knowledge, high taxes, and favoritism benefiting the largest wine producers in the industry. Originality/value – The paper closes with suggestions for future research on how phenomena such as the relationship strategies established by the wineries impact upon internationalization and how decisions of a political nature made by formal institutions influence the wine industry, providing a new outlook on the internationalization of these firms.

  1. De-Internationalization of Universities

    DEFF Research Database (Denmark)

    Turcan, Romeo V.; Gulieva, Valeria

    Alongside student and staff mobility, universities these days get also actively involved in out-ward cross-border activities, such as licensing, entering joint ventures and establishing campuses. These cross-border activities are not without pitfalls however. A large number of universities de-int...... on withdrawals from franchise, joint venture, and branch campus operations. We use the concept of de-internationalization as a theoretical lens and conduct a review of available unobtrusive data to identify reasons and patterns of universities' withdrawals from international markets....

  2. Internationalization and university cooperation

    OpenAIRE

    Parra-Chacón Edgar

    2010-01-01

    La Conferencia Mundial de Educación Superior realizada en Paris en el año de 1998, enfatizó que las Instituciones de Educación Superior (IES) han de enfocar los esfuerzos de desarrollo a las siguientes prioridades: la calidad, la pertinencia y la cooperación internacional (1).La segunda Conferencia Mundial de Educación Superior realizada en Paris en el año de 2009, avanza en los postulados sobre los fines de la formación de nivel superior y señala: La Educación Superior debe no sólo proporcio...

  3. Paris Offscreen: Chinese Tourists in Cinematic Paris

    NARCIS (Netherlands)

    Y.-A. O. Dung (Yun-An Olivia); S.L. Reijnders (Stijn)

    2013-01-01

    markdownabstract__Abstract__ This article examines from a European-Asian perspective the relationship between media representations and the tourist’s imagination. We use the case of Chinese tourists in Paris to investigate how these non-European tourists imagine Europe, and how these imaginations

  4. Shanghai Pilot Free Trade Zone: A Test For Renminbi Internationalization?

    Directory of Open Access Journals (Sweden)

    Han Long

    2017-10-01

    Full Text Available China(Shanghai)Pilot Free Trade Zone (“SHFTZ” as well as other Pilot Free Trade Zones established in China carries on the mission to make the test for, inter alia, China’s strategic financial reforms and for Renminbi(“RMB” internationalization in particular. However, the financial reforms in SHFTZ according to its design and relevant provisions can only provide very limited rather than fully effective test for the reforms of free convertibility, international capital transactions as well as risk hedging needed by RMB internationalization. The aim of the paper is to investigate the test effect that SHFTZ have on the above capital account reforms. It argues that the main reason for the test failure lies in “outward free and inward control” mode designed for SHFTZ which makes it an insulated customs territory, a situation which differs from the circumstances in which a currency gets internationalized. Moreover, SHFTZ runs the risk of evolving into an offshore RMB market set up inside China, a trend China should prevent because it cannot serve the testing missions mentioned above.

  5. THE PROCESS OF INTERNATIONALIZATION OF SOFTWARE FIRMS: THE CASE AUDACES

    Directory of Open Access Journals (Sweden)

    Antonia Egidia Souza

    2012-10-01

    Full Text Available This study addresses the way in which Brazilian companies are internationalising, their motivations for internationalization and competitive advantage in this process. The article analyzes in depth a software company that since 2002 has been working successfully in the global market. The theoretical framework used is supported in three major theories on the internationalization: the advantage of ownership (DUNNING, 1988, the Uppsala School of the 1970s and the born global theory (RENNIE, 1993; CAVUSGIL and KNIGHT, 1996; OVIATT and McDougall, 1994; MADSEN and SERBIA, 1997. To conduct the study, using a qualitative approach with an exploratory-descriptive approach. The strategy was the case study. Data were collected from primary and secondary sources. The data analysis was from the content analysis. As a result, it appears that the motivation for the internationalization is based on the need to reduce dependence on domestic market, ability to modify products for the international market opportunity for profit and growth in the international market, interest management for international activities.

  6. Internationalization of Bachelor’s programmes in Social Work in Europe

    Directory of Open Access Journals (Sweden)

    Peter Hendriks

    2016-03-01

    Full Text Available Internationalization of Bachelor’s programmes in Social Work in EuropeThis article presents the results of a survey on the internationalization of Bachelor’s education in social work, which was carried out at 33 schools of social work across Europe. Many universities are seeking to “internationalize” their social work curriculum. However, although many social work educators are convinced of the importance of cross-border exchange, others are sceptical about the added value of internationalization for a professional career in social work. The aim of this study is to contribute to the discussion about the significance of internationalizing the curriculum of Bachelor’s programmes in social work. Since internationalization in itself is an ideological endeavour, educators must reflect on and formulate their own ideological motives and aspirations. To this end, representatives of schools of social work completed a questionnaire concerning the aim of internationalization, the structure of the curriculum, student and staff mobility, international policies and challenges. This study demonstrates that all universities have added an international dimension to their curricula. Many educators believe that internationalizing the social work curriculum contributes to qualitatively better future professionals “at home”. However, most of the respondents are dissatisfied with what has actually been achieved in terms of their universities’ international ambitions. This is due to a lack of language skills and facilities. Above all, we think, that this dissatisfaction is related to the underlying debate on universalism and indigenization in social work practice and education.  SAMENVATTINGDe internationalisering van de bachelors sociaal werk in EuropaIn dit artikel worden de uitkomsten gepresenteerd van een survey naar internationalisering van het sociaal werk bachelor onderwijs, uitgevoerd onder 33 opleidingen sociaal werk, verspreid over Europa

  7. Expatriation on the strategy of internationalized companies

    Directory of Open Access Journals (Sweden)

    Shalimar Gallon

    2014-12-01

    Full Text Available This paper analyses the strategic role of the expatriation in the internationalization of the company. Expatriation should be minded as the result of a broader organizational strategy, representing one of the ways to articulate international and local strategies. A case study made on the Alpha Company has been presented in which 21 interviews were performed with professionals of the area and expatriates/repatriates. Alpha company has very emphasis in the world scenario and has a expatriation program of 12 years, nevertheless, has a lack of polices and more structured practices, due to its internationalization has been taken a larger dimension as the company was ready to deal with. It is pointed, however, that the same process have permitted several growing possibilities for professionals and the company as has presented many challenges to be overcome, like enhancement of the process training, repatriation planning, valorization and retention of the repatriate

  8. Research on the Development Route of Internationalization Brand of Sports Nutrition Food

    OpenAIRE

    Haifang Zhang

    2015-01-01

    In this study, it takes the interpretation of internationalization brand of sports nutrition food as the cutting point, by means of explaining the difficulties that Chinese sports nutrition food brand encountered at the present stage to explore the route of realizing the internationalization brand of sports nutrition food. With the rapid development of Chinese economic growth, the brand of Chinese sports nutrition food is also facing the fierce global market competition.

  9. Glocalization as an Alternative to Internationalization in Higher Education: Embedding Positive Glocal Learning Perspectives

    Science.gov (United States)

    Patel, Fay; Lynch, Hayley

    2013-01-01

    The notion of internationalization in higher education is understood as the recruitment of international students, marketing of academic programs and courses, and teaching English as a Second Language to student cohorts from Asia, Africa, and Latin America. Various models of internationalization (Knight, 2004, 2006; Leask, 2009; Pimpa, 2009;…

  10. The importance of residues 195-206 of human blood clotting factor VII in the interaction of factor VII with tissue factor

    International Nuclear Information System (INIS)

    Wildgoose, P.; Kisiel, W.; Kazim, A.L.

    1990-01-01

    Previous studies indicated that human and bovine factor VII exhibit 71% amino acid sequence identity. In the present study, competition binding experiments revealed that the interaction of human factor VII with cell-surface human tissue factor was not inhibited by 100-fold molar excess of bovine factor VII. This finding indicated that bovine and human factor VII are not structurally homologous in the region(s) where human factor VII interacts with human tissue factor. On this premise, the authors synthesized three peptides corresponding to regions of human factor VII that exhibited marked structural dissimilarity to bovine factor VII; these regions of dissimilarity included residues 195-206, 263-274, and 314-326. Peptide 195-206 inhibited the interaction of factor VII with cell-surface tissue factor and the activation of factor X by a complex of factor VIIa and tissue factor half-maximally at concentrations of 1-2 mM. A structurally rearranged form of peptide 195-206 containing an aspartimide residue inhibited these reactions half-maximally at concentrations of 250-300 μM. In contrast, neither peptide 263-274 nor peptide 314-326, at 2 mM concentration, significantly affected either factor VIIa interaction with tissue factor or factor VIIa-mediated activation of factor X. The data provide presumptive evidence that residues 195-206 of human factor VII are involved in the interaction of human factor VII with the extracellular domain of human tissue factor apoprotein

  11. Uncertainty in the family business facing the process of internationalization: Literature review and future research agenda

    Directory of Open Access Journals (Sweden)

    Quico Marin

    2014-12-01

    Full Text Available Purpose: This article analyses the Family Business (FB within the process of globalization that has been taking place in recent decades.Design / methodology / approach: To achieve this we undertake a description of the importance of FB in the global economy and contrast this with a systematic review of the academic literature, which demonstrates the growing academic interest in the internationalization of the FB.Findings: The literature review highlights the importance of agency and stewardship theories when analyzing the aspects that affect the process of internationalization. These theoretical frameworks require a variety of assumptions and explain how ownership and control of an FB may explain different attitudes towards some short term risks, which could be due to FB politics of internationalization.Research limitations / implications: Finally, we mark out future research lines which will focus on the effect the ownership structure has on the type of internationalization that is undertaken by the FB.Originality / value: This article outlines new lines of literature review in the FB internationalization field, suggesting to the future authors the outstanding journals and topics in this research field.

  12. Balancing Economic and Other Discourses in the Internationalization of Higher Education in South Africa

    Science.gov (United States)

    Dunn, Mel; Nilan, Pam

    2007-01-01

    Since the end of the apartheid era in South Africa, "internationalization" of higher education has been a popular theme as the country takes its place as a regional leader in education and research in sub-Saharan Africa. However, competing discourses of internationalization have produced economic and moral dilemmas rather than the…

  13. Newly diagnosed congenital factor VII deficiency and utilization of recombinant activated factor VII (NovoSeven(®)).

    Science.gov (United States)

    Bartosh, Nicole S; Tomlin, Tara; Cable, Christian; Halka, Kathleen

    2013-01-01

    This case report presents a newly diagnosed congenital factor VII deficiency treated with recombinant activated factor VII (rFVIIa). Congenital factor VII deficiency is a rare autosomal-recessive bleeding disorder that occurs in fewer than 1/500,000 persons. Its presentation can vary from epistaxis to hemarthroses and severe central nervous system bleeding, and correlates poorly with factor VII levels. Our patient had not had a significant hemostatic challenge prior to his presentation and therefore never had any symptomatology suggestive of this disease. He was treated with rFVIIa, and was able to undergo repair of his fractures without bleeding. A 19-year-old African-American male presented to the emergency room after an altercation that resulted in significant trauma. He sustained bilateral mandibular angle fractures and orbital floor fractures, requiring urgent surgical correction. On initial evaluation, he was noted to have a prolonged prothrombin time of 40.1 seconds, with an International Normalized Ratio of 4.0, a normal activated partial thromboplastin time of 29.9 seconds, and a platelet count of 241. After receiving vitamin K and fresh frozen plasma, he was taken to the operating room for a temporary rigid maxillomandibular fixation. A 1:1 mixing study with normal plasma corrected the prothrombin time (decreasing from 40.7 to 14.7 seconds) and a factor VII assay revealed 5% of the normal factor VII level. The patient was diagnosed with congenital factor VII deficiency. Due to his coagulopathy and the extensive surgical correction needed, rFVIIa was administered and surgery was accomplished without hemorrhagic sequelae. This case report and review describes a rare congenital disease, the history of rFVIIa use, and its mechanism. rFVIIA use in our patient provided a treatment option that allowed the necessary surgical correction, but further prospective studies on dose optimization would ensure adequate dosing with minimal risk of severe side effects.

  14. Genetics Home Reference: glycogen storage disease type VII

    Science.gov (United States)

    ... Home Health Conditions Glycogen storage disease type VII Glycogen storage disease type VII Printable PDF Open All ... Javascript to view the expand/collapse boxes. Description Glycogen storage disease type VII (GSDVII) is an inherited ...

  15. Cultural distance and the process of firm internationalization : A meta-analytical review and theoretical implications

    NARCIS (Netherlands)

    Beugelsdijk, S.; Kostova, T.; Kunst, Vincent E; Spadafora, Ettore; van Essen, M.

    This paper presents the most comprehensive review and meta-analysis of the literature on cultural distance and firm internationalization to date. We analyze the effects of cultural distance on key strategic decisions throughout the entire process of internationalization. For the preinvestment stage,

  16. Living with Internationalization: The Changing Face of the Academic Life of Chinese Social Scientists

    Science.gov (United States)

    Xie, Meng

    2018-01-01

    Internationalization is an integral part of the strategies of leading Chinese universities to strive for world-class standing. It has left its marks on the academic life of China's social scientists. This article explores the impact of internationalization on the academic life of Chinese social scientists using Tsinghua University as an example.…

  17. An Empirical Investigation of the Role of Industry Factors in the Internationalization Patterns of Firms

    DEFF Research Database (Denmark)

    Grøgaard, Birgitte; Gioia, Carmine; Benito, Gabriel R. G.

    examines the role of such factors using data covering the internationalization patterns of the 100 largest non-financial Norwegian companies over the period 1990 to 2000. We find that industry factors contribute significantly to explaining the internationalization of these companies, and that the effects...

  18. Franchising and the internationalization of businesses: the case of fast food chains

    OpenAIRE

    Fadil Alnassar

    2017-01-01

    The objective of this paper is to investigate the role of franchising in the process of internationalization of the fast food industry. The paper hypothesizes that franchising is an effective means of internationalization in the fast food industry that increases the revenues of the company. The hypothesis of the paper will be tested using the linear regression analysis. This analysis studies the relationship between revenues (dependent variable) and the number of outlets and the number of emp...

  19. Top management team internationalization and firm-level internationalization : The moderating effects of home-region institutional diversity and firm global focus

    NARCIS (Netherlands)

    Pisani, Niccolò; Muller, Alan; Bogățan, Paula

    2018-01-01

    The factors that determine firms’ levels of internationalization remain a focal area of international business research. Within this research stream, studies building on the upper echelons theory have investigated the influence of the demographic characteristics of the top management team (TMT) on

  20. Paris

    Science.gov (United States)

    2001-01-01

    [figure removed for brevity, see original site] Figure 1 This image of Paris was acquired on July 23, 2000 and covers an area of 23 by 20 km. Known as the City of Light, Paris has been extolled for centuries as one of the great cities of the world. Its location on the Seine River, at a strategic crossroads of land and river routes, has been the key to its expansion since the Parisii tribe first settled here in the 3rd century BC. Paris is an alluring city boasting many monumental landmarks, such as the Cathedral of Notre Dame, the Louvre, and the Eiffel Tower. Its beautiful gardens, world-class cuisine, high fashion, sidewalk cafes, and intellectual endeavors are well known. The city's cultural life is centered on the Left Bank of the Seine, while business and commerce dominate the Right Bank. The image is located at 48.8 degrees north latitude and 2.3 degrees east longitude. In figure 1, the 4 enlarged areas zoom in to some of the major buildings. In the UPPER LEFT, the Eiffel Tower and its shadow are seen. Based on the length of the shadow and the solar elevation angle of 59 degrees, we can calculate its height as 324 m (1054 ft), compared to its actual height of 303 m (985 ft). In the UPPER RIGHT, the Arc de Triomphe is at the center of the Place de L'etoile, from which radiate 12 major boulevards. In the LOWER LEFT is the Tuileries Garden and the Louvre Museum art its eastern end. In the LOWER RIGHT is the Invalides, the burial place and monument of Napoleon Bonaparte. The U.S. science team is located at NASA's Jet Propulsion Laboratory, Pasadena, Calif. The Terra mission is part of NASA's Science Mission Directorate.

  1. Stimulating the Competitiveness of the Macedonian Economy through the Process of Stimulation the Internationalization of the Companies

    Directory of Open Access Journals (Sweden)

    Jovanka Damoska Sekuloska

    2015-08-01

    Full Text Available The research in this paper is to be focused on examining the internationalization of the Macedonian companies as a prerequisite in improvement of Macedonian competitiveness. Internationalization as a process of integration in international economic activities contributes to overcome the sizes of national markets. According to the World Economic Forum (WEF the size of the market is one of the pillars of competitiveness and it is revealed as one of the limitation of the competitiveness of Macedonian economy. The contemporary theories of competitiveness recognize the necessity of quantitative and qualitative improvement of the process of internationalization of the companies. Quantitative improvement means involving not only trade but also outward FDI and the new quality signifies the necessity of restructuring the economic activities towards employing and creating innovation based processes, as (Porter, 1990accents that a nation’s competitiveness depends on the capacity of its industry to innovate and upgrade. Using data of some target Central European and Baltic (CEB economies, it will be examined interrelationships between the internationalization and competitiveness and policies that influence the improvement and stimulation of internationalization process.

  2. Study Abroad Programs as Tools of Internationalization: Which Factors Influence Hungarian Business Students to Participate?

    Science.gov (United States)

    Huják, Janka

    2015-01-01

    The internationalization of higher education has been on the agenda for decades now all over the world. Study abroad programs are undoubtedly tools of the internationalization endeavors. The ERASMUS Student Mobility Program is one of the flagships of the European Union's educational exchange programs implicitly aiming for the internationalization…

  3. First living-related liver transplant to cure factor VII deficiency.

    Science.gov (United States)

    Mohan, Neelam; Karkra, Sakshi; Jolly, Anu S; Vohra, Vijay; Mohanka, Ravi; Rastogi, Amit; Soin, A S

    2015-09-01

    Congenital factor VII deficiency is an autosomal recessive serious disorder of blood coagulation with wide genotypic and phenotypic variations. The clinical presentation can vary from asymptomatic patients to patients with major bleedings in severe deficiency (factor VII factor VII. Treatment modalities include FFP and repeated recombinant factor VII infusions. We hereby report the first successful LRLT for factor VII deficiency in an infant, the first-ever youngest baby reported worldwide. A six-month-old male child presented with easy bruisability, ecchymotic patches, hematuria, and convulsions. CT of the head showed subdural hemorrhage, which was treated conservatively. He had markedly increased PT (120 s) with normal platelets, and aPTT with factor VII level factor VII level was 57%. A factor VII infusion plan for pre-, intra- and postoperative periods was formulated and TEG followed. Postoperatively, his factor VII started increasing from third day and was 38% on 24th day with PT factor VII deficiency. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  4. Coping with Risk in the Internationalization of SMEs

    DEFF Research Database (Denmark)

    Eduardsen, Jonas Strømfeldt; Marinova, Svetla Trifonova

    2015-01-01

    managerial perceptions influence risk accommodation. Semi-structured interviews were used to explore experiences of a group of international Danish SMEs. Findings show that SMEs follow different strategies of coping with risk and uncertainty in the internationalization process depending on key decision...

  5. Newly diagnosed congenital factor VII deficiency and utilization of recombinant activated factor VII (NovoSeven®)

    Science.gov (United States)

    Bartosh, Nicole S; Tomlin, Tara; Cable, Christian; Halka, Kathleen

    2013-01-01

    This case report presents a newly diagnosed congenital factor VII deficiency treated with recombinant activated factor VII (rFVIIa). Congenital factor VII deficiency is a rare autosomal-recessive bleeding disorder that occurs in fewer than 1/500,000 persons. Its presentation can vary from epistaxis to hemarthroses and severe central nervous system bleeding, and correlates poorly with factor VII levels. Our patient had not had a significant hemostatic challenge prior to his presentation and therefore never had any symptomatology suggestive of this disease. He was treated with rFVIIa, and was able to undergo repair of his fractures without bleeding. Case report A 19-year-old African-American male presented to the emergency room after an altercation that resulted in significant trauma. He sustained bilateral mandibular angle fractures and orbital floor fractures, requiring urgent surgical correction. On initial evaluation, he was noted to have a prolonged prothrombin time of 40.1 seconds, with an International Normalized Ratio of 4.0, a normal activated partial thromboplastin time of 29.9 seconds, and a platelet count of 241. After receiving vitamin K and fresh frozen plasma, he was taken to the operating room for a temporary rigid maxillomandibular fixation. A 1:1 mixing study with normal plasma corrected the prothrombin time (decreasing from 40.7 to 14.7 seconds) and a factor VII assay revealed 5% of the normal factor VII level. The patient was diagnosed with congenital factor VII deficiency. Due to his coagulopathy and the extensive surgical correction needed, rFVIIa was administered and surgery was accomplished without hemorrhagic sequelae. Conclusion This case report and review describes a rare congenital disease, the history of rFVIIa use, and its mechanism. rFVIIA use in our patient provided a treatment option that allowed the necessary surgical correction, but further prospective studies on dose optimization would ensure adequate dosing with minimal risk of

  6. Flippable User Interfaces for Internationalization

    OpenAIRE

    Khaddam, Iyad; Vanderdonckt, Jean; 3rd ACM Symposium on Engineering Interactive Computing Systems EICS’2011

    2011-01-01

    The language reading direction is probably one of the most determinant factors influencing the successful internationalization of graphical user interfaces, beyond their mere translation. Western languages are read from left to right and top to bottom, while Arabic languages and Hebrew are read from right to left and top to bottom, and Oriental languages are read from top to bottom. In order to address this challenge, we introduce flippable user interfaces that enable the end user to change t...

  7. Role of hepsin in factor VII activation in zebrafish.

    Science.gov (United States)

    Khandekar, Gauri; Jagadeeswaran, Pudur

    2014-01-01

    Factor VII, the initiator of the extrinsic coagulation cascade, circulates in human plasma mainly in its zymogen form, factor VII and in small amounts in its activated form, factor VIIa. However, the mechanism of initial generation of factor VIIa is not known despite intensive research using currently available model systems. Earlier findings suggested serine proteases factor VII activating protease and hepsin play a role in activating factor VII, however, it has remained controversial. In this paper we estimated the levels of factor VIIa and factor VII for the first time in zebrafish adult population and also reevaluated the role of the above two serine proteases in activating factor VII in vivo using zebrafish as a model system. Knockdown of factor VII activating protease and hepsin was performed followed by assaying for their effect on factor VIIa concentration and extrinsic coagulation as measured by the kinetic prothrombin time. Factor VII activating protease knockdown showed no change in kinetic prothrombin time and no effect on factor VIIa levels while hepsin knockdown increased the kinetic prothrombin time and significantly reduced the factor VIIa plasma levels. Our results thus indicate that hepsin plays a physiologically important role in factor VII activation and hemostasis in zebrafish. © 2013.

  8. Accelerated Internationalization in Emerging Markets: Empirical Evidence from Brazilian Technology-Based Firms

    Directory of Open Access Journals (Sweden)

    Fernanda Ferreira Ribeiro

    2014-04-01

    Full Text Available This paper offers an analysis into the external factors influencing the accelerated internationalization of technology-based firms (TBFs in the context of an emerging country, Brazil. This type of firm is typically called born global and has been reported mainly in high technology sectors and from developed countries. A survey was applied to small and medium Brazilian TBFs. Logistic regression was used to test the research hypotheses. The results suggest that new and small Brazilian technology-based firms, which followed an accelerated internationalization process, are most likely to be integrated into a global production chain. Results also show that TBFs which take more than five years to enter the international market, benefit more from the location in an innovation habitat, the partnerships in the home country, and the pro-internationalization government policies. Therefore, this research contributes to a better understanding of the phenomenon and points to new perspectives of studies.

  9. The Effects of Past Satisfaction and Commitment on the Future Intention to Internationalize

    DEFF Research Database (Denmark)

    Ramsey, Jase R.; Barakat, Livia; Mitchell, Matthew C.

    2016-01-01

    literature, the degree to which a firm was committed to internationalization has a negative influence on the positive relationship between satisfaction and intent. Design/methodology/approach: – All Brazilian firms that have entered foreign markets via FDI were surveyed to measure the firm’s: intent...... Paulo Stock Exchange) and private limited companies (Ltda.). The authors conducted a hierarchical moderated regression analysis to test the moderating effect of commitment to internationalization on the relationship between international satisfaction and intent to internationalize. Findings...... enough data points to test more hypotheses such as the effects of firm size, number of countries the firm is in, and age of the firm. Future studies should attempt to expand the work done here by examining these effects. Another limitation of this study is that it is based on solely one country; Brazil...

  10. Analysis of internationalization process of Bric countries with the Grubel and Lloyd index

    Directory of Open Access Journals (Sweden)

    Pedro Raffy Vartanian

    2013-08-01

    Full Text Available This research aims to show the internationalization of the BRIC (Brazil, Russia, India and China through the application of the Grubel and Lloyd index in the period 1994-2009. The hypothesis is that the BRIC countries have shown a growth in the internationalization process, as reflected by increased levels of productive investment in other countries. The research is the application method of the Grubel and Lloyd index in the flows of foreign direct investment and foreign investment by residents abroad in the period 1994-2009, in the BRIC countries. The results showed an increase in the Grubel and Lloyd index related to foreign investment flows, which suggests that companies from the BRIC countries have been increasing productive investment in other countries by the same way that the companies from the advanced economies in order to maximize profits through internationalization.

  11. FRANCHISING AS A MEANS OF ACHIEVING INTERNATIONALIZATION: RESEARCH PROPOSITIONS FROM A MULTIPLE CASE STUDY OF BRAZILIAN FASHION RETAILERS

    OpenAIRE

    Victor Manoel Cunha de Almeida; Felipe Mendes Borini; Thiago Cruz Silveira; Ilan Avrichir

    2015-01-01

    According to Brazilian Franchising Association, the number of Brazilian franchises has grown 300% in the last ten years, but only 3% of Brazilian franchises operate in foreign markets, so the opportunity to internationalization is strong. Aiming to get a better understanding of possible distinctive features of Brazilian retail internationalization, this paper explores the determinants of franchising as the choice of internationalization entry mode by Brazilian’s firms in the fashion apparel s...

  12. Aligning Institutional and National Contexts with Internationalization Efforts

    Science.gov (United States)

    Johnstone, Christopher; Proctor, Douglas

    2018-01-01

    In this article we report on our study that explored internationalization in higher education institutions as it relates to two levels of "culture"--institutional culture and national higher education culture. We examined two leading research-intensive universities, "Coastal University" (Australia) and "Prairie…

  13. Internationalization of high-technology ventures from emerging economies

    DEFF Research Database (Denmark)

    Turcan, Romeo V.

    This paper aims to contribute towards filling in the gap in the international entrepreneurhsip literature by exploring how and why new high-technology ventures internationalize from an emerging economy, namely Moldova. To address the above research questions, a multiple-case study strategy...

  14. Hotel chains of the global South: The internationalization of South African hotel brands

    OpenAIRE

    Rogerson, Jayne M.

    2016-01-01

    The global hotel industry is at the heart of the tourism production system and dominated by chain affiliated hotels. Understanding the international spread of hotel chains is a critical issue in contemporary tourism scholarship. Although the internationalization of hotel chains based in the global North is extensively researched, limited work exists on hotel chains based in the global South. This paper addresses the internationalization and destination choice in Africa of South African based ...

  15. Use of recombinant factor VII for tooth extractions in a patient with severe congenital factor VII deficiency: a case report.

    Science.gov (United States)

    Weinstock, Robert J; Onyejiuwa, Andrew; Shnayder, Garry; Clarkson, Earl I

    2015-04-01

    Patients with factor VII deficiency have an increased risk of prolonged perioperative hemorrhage. In this article, the authors present a case of severe factor VII deficiency in a patient who required tooth extraction. A 44-year-old woman with severe congenital factor VII deficiency sought care for a symptomatic, carious, and nonrestorable maxillary right second molar that required extraction. The authors obtained hematologic consultation, and the patient underwent the extraction under general anesthesia in the inpatient setting. Perioperative management included performing relevant laboratory studies, preoperative recombinant factor VII infusion, and postoperative intravenous aminocaproic acid administration. No hemorrhagic complications occurred throughout the perioperative course. The degree of factor VII deficiency correlates poorly with bleeding risk. Perioperative management is variable, requiring preoperative consultation with a hematologist. Copyright © 2015 American Dental Association. Published by Elsevier Inc. All rights reserved.

  16. Synergistic effect of factor VII gene polymorphisms causing mild factor VII deficiency in a case of severe factor X deficiency.

    Science.gov (United States)

    Deshpande, Rutuja; Ghosh, Kanjaksha; Shetty, Shrimati

    2017-01-01

    Congenital combined deficiency of coagulation factors VII and X are mainly attributed to large deletions involving both the genes in chromosome 13 or occasionally due to the coincidental occurrence of independently occurring mutations. We report the molecular basis of congenital combined deficiency of factors VII and X in a 6-year-old female child. Direct DNA sequencing of both factor VII (F7) and factor X (F10) genes showed a novel homozygous missense mutation p.Cys90Tyr (c.307G>A) in exon 4 of F10. No mutations were detected in F7; however, the patient was homozygous for three polymorphic alleles known to be associated with reduced factor VII levels. The present case illustrates the synergistic effect of multiple polymorphisms resulting in phenotypic factor VII deficiency in the absence of a pathogenic mutation.

  17. Internationalization Process of Thai Office Furniture Company in India: A case study of Rockworth Public Company Limited

    OpenAIRE

    netwong, weeraya; trakarnthai, priyawat

    2010-01-01

    The purpose of this thesis is to study the internationalization process by investigate how Rockworth Public Company Limited manage internationalization in Indian market efficiently. Additionally, we aim to improve our understanding and knowledge in international business comprehensively.

  18. Internationalization Of Indian IT Multinationals

    OpenAIRE

    Singh, Abhishek

    2009-01-01

    Indian IT industry has emerged to be a strong and influential player on the world map. The industry which did not existed a few decades ago is now a major exporter of software services to major markets. The Indian IT firms now seem to move beyond exporting and advance further into the international market. With the help of case study approach, this study tends to examine the internationalization of these firms. The dissertation is aimed to see how far the traditional theories o...

  19. THE INTERNATIONALIZATION PROCESS OF AN FASHION SOFTWARE

    Directory of Open Access Journals (Sweden)

    William Ramos

    2011-06-01

    Full Text Available This paper aims to analyze the internationalization process from 1996 to 2010 of a company that develops software for fashion. The theoretical foundations of the article include the theories of internationalization with special attention to the Nordic School of International Business, the approach of the networks, as well as research on specific software firms, born globals and international entrepreneurship. The survey used the technique of case study, qualitative, exploratory and descriptive. Data were collected from primary sources such as semi-structured interviews and questionnaires, and secondary sources. The data from the interviews and documents were repeatedly reviewed, coded and analyzed for their content and meaning, to identify the categories under consideration. Among the factors seen fleeing theoretical approaches, are cited the heels of the steps outlined by them and not exclusive preference for countries with lower psychic distance. It was also relevant to the international orientation of the entrepreneurs, whose social networks encompassed international actors who sometimes influenced the process, confirming the approach of the networks.

  20. Small Firms in a Small Country: Managerial Factors, Internationalization and Performance of Slovenian SMEs

    OpenAIRE

    Mariola Ciszewska-Mlinarič; Franjo Mlinarič

    2010-01-01

    International activities of small and medium enterprises (SMEs) constitute an important research area. To understand this phenomenon, researchers employ different theoretical perspectives. Among them, the resource-based theory has been given much attention. In this study three managerial factors: managerial attitude toward internationalization, internationalization knowledge and international experience, are seen as examples of the firm’s intangible assets. The objectives of this study are tw...

  1. Methodology for Assessing the Degree of Internationalization of Business Academic Study Programmes

    Directory of Open Access Journals (Sweden)

    Dan-Cristian Dabija

    2014-08-01

    Full Text Available The purpose of this paper is to develop a methodology for assessing the degree of internationalization of undergraduate, Master’s and doctoral business programmes with the aid of complex indicators designed to capture the vast array of characteristics displayed by these programmes and contribute to their promotion in the international academic competition. The methodology should include both general indicators applicable to any study programme and some indicators that are specifically developed for business study programmes. No consensus exists in the internationalization literature and practice over the actual scope and the indicators to be considered in the implementation of such a study. Researchers rather propose methods for assessing and prioritizing universities and/or faculties and lay down a lot of criteria according to which rankings are developed. These rankings are mainly focused on the level of internationalization of socioeconomic and engineering study programmes. Being aware of the limits of theory and practice, the authors develop a scoring model that measures the degree of internationalization of business education curricula according to stringent criteria. The research originality lies in the attempt to describe the avenues of a new methodology for measuring and assessing realistically the economic study programmes so that these may be better positioned on the educational market and become more attractive to the future candidates. Based on a synergistic approach to indicators, the model may contribute to creating competitive advantage in relation to other programmes from the same university or from partner institutions.

  2. Economy globalization and internationalization of business

    OpenAIRE

    Lucia PALIU-POPA

    2009-01-01

    In the conditions of contemporary world, the active participation in international division of labor is an essential component of the development process of each country. In this context the foreign trade, as a distinct branch of the national economy is an important factor of economic growth caused by the internationalization of business and determining for the process of globalization. Starting from the belief that international business development tends to bec...

  3. The Lure of Internationalization: Paradoxical Discourses of Transnational Student Mobility, Linguistic Diversity and Cross-Cultural Exchange

    Science.gov (United States)

    Fabricius, Anne H.; Mortensen, Janus; Haberland, Hartmut

    2017-01-01

    This paper scrutinizes a set of paradoxes arising from a mismatch between contemporary discourses that praise and promote mobility in and internationalization of higher education, and the everyday effects of mobility and internationalization on university teaching and learning practice. We begin with a general characterization of the discourse of…

  4. Organizational Culture and Internationalization: A Brief Literature Review

    Science.gov (United States)

    Nussbaumer, Alison

    2013-01-01

    This brief literature review introduces an area of emerging research about the impact of organizational culture on institutional strategies for internationalization. The review begins by introducing the concept of organizational culture, particularly within higher education. Five articles published between 2003 and 2012 are examined that introduce…

  5. From Penrith to Paris

    Directory of Open Access Journals (Sweden)

    Katherine Elizabeth Clay

    2006-09-01

    Full Text Available Katherine Clay has written her first graphic novel, 'From Penrith to Paris', based on experiences of her first semester in France. It deals with the issues of student life, the loss of cultural identity through language and what it means to come from the cultural wasteland of Sydney to the cultural capital of the world - Paris. Through these funny and often life changing experiences, she realises the value of her hometown and that culture, no matter how it is perceived, plays an enormous role in the shaping of individuals.

  6. H3 internationalization to Brazil

    OpenAIRE

    Carona, Eduardo João Bonneville Torres

    2012-01-01

    A Work Project, presented as part of the requirements for the Award of a Masters Degree in Management from the NOVA – School of Business and Economics h3 is a Portuguese firm competing in the fast food market with a hamburger gourmet concept. The firm is now a strong player in Portugal (39 stores); Poland, Warsaw (1 store); Spain, Madrid (1 store) and Brazil, São Paulo (2 stores). As a result of their successes in the domestic market, internationalization was a natural step. One o...

  7. Tracking the Traces of Intercultural Dialogue in Internationalization Policies of Three EU Universities: Towards a Framework

    Science.gov (United States)

    Woodin, Jane; Lundgren, Ulla; Castro, Paloma

    2011-01-01

    The internationalization of higher education has been a major concern in the last decades for a variety of reasons. This concern has been addressed by policymakers in a number of ways, most commonly through increased international partnerships and recruitment of international students. Much of the underlying motivation for internationalization is…

  8. The Strategy of De-Internationalization of the SMES of the Footwear in the Area Metropolitana de Guadalajara

    Directory of Open Access Journals (Sweden)

    José G. VARGAS-HERNÁNDEZ

    2011-09-01

    Full Text Available The aim of this paper is to analyze the exogenous and endogenous factors that determine the strategy of de-internationalization of SMEs in the sector of the footwear in the Metropolitan Zone of Guadalajara (ZMG. A model is proposed that explains the adoption of the strategy of de-internationalization from studies of comparative case in SMEs in the footwear sector of the ZMG. In-depth interviews were applied to managers and staff involved during the time that the company was exporting. Analysis points out that lack of strategic planning and the instability in the foreign currency exchange rate are major factors that determine the strategy of de-internationalization in SMEs in the ZMG. Also, it is evident that the strategic imbalance during the de-internationalization strategy is not considered as a failure, but rather as an opportunity to redirect it and thus grow in the local market

  9. Determinants of Investment Opportunity Set (Degree of Internationalization and Macroeconomic Variables

    Directory of Open Access Journals (Sweden)

    Cynthia utama

    2015-08-01

    Full Text Available The aim of this study is to investigate the influence of internal factors (i.e. the degree of internationalization, profitability, firm size, and financial leverage and external factors (i.e. GNP growth and the inflation rate on firms’ growth opportunities or their Investment Opportunity Set (IOS. The IOS is measured by the market-to-book assets ratio. The result shows that profitability and firms’ size have a positive impact on the IOS whereas the degree of internationalization and financial leverage has a negative influence on the IOS. Finally, the IOS is positively affected by GNP growth while the inflation rate has a negative impact on IOS.

  10. Legitimation for Early and Rapid Internationalization: A Review of Research in International Entrepreneurship

    DEFF Research Database (Denmark)

    Laine, Igor; Kuivalainen, Olli; Marinova, Svetla Trifonova

    In this paper we respond to Cavusgil and Knight’s call for future research to address the question of born global firms overcome inherent liabilities to achieve legitimacy in foreign markets. To contribute to this call, we have systematically reviewed the extant international entrepreneurship...... literature. By analyzing existing evidence on building organizational legitimacy by early and rapidly internationalizing firms, our review helps to understand reasons and underlying mechanisms of successful legitimation of early and rapid internationalization thus ultimately explaining existence...... entrepreneurship....

  11. The Impacts of Internationalization and Globalization on Educational Context

    Directory of Open Access Journals (Sweden)

    Hendra Heriansyah

    2014-05-01

    Full Text Available This paper addresses the impacts of internationalization and globalization on educational context. It is undeniable that the presence and existence of globalization have brought and given a great deal of influences within various fields including on education sector. Of course, it will be a problematic if a school or a higher education institution does not comprehensively notice and precisely pay attention towards each effect and development from internationalization and globalization that obviously appear. Hence, it is needed an international curriculum design that has the meticulous content and process as well as assessment. Moreover, the curriculum also has to take account a variety of aspects and components from distinctive perspectives within its plan, array, and implementation in the field in order to meet the demands of global marketplace and be able to answer each of challenges and changes that arise.

  12. Project management as a competitive advantage for the internationalization of Brazilian companies

    Directory of Open Access Journals (Sweden)

    Andre Luiz Spinelli Schelini

    2017-12-01

    Full Text Available This study focuses on three theoretical axes: project management (PM, internationalization of companies and the resource-based view (RBV. It aimed to analyze if, and in what way, PM maturity contributes to the international strategy of Brazilian companies from the RBV perspective. The research strategy adopted in three Brazilian companies constituted a multiple case study with a descriptive exploratory approach through intercase and intracase analysis. As an unprecedented result, the study identified five characteristics of mature project management: project sustainability, stakeholder engagement, goal setting and strategy, change management, and risk management. Furthermore, all of these contributed to the internationalization of the companies in question, with an impact on competitive advantage, considering the RBV-VRIO analysis. Thus, the study contributes to the field by aiding companies that are beginning or intend to begin internationalization processes, enabling them to obtain better results through PM. A limitation of the study is the small number of cases investigated, which may be viewed as an opportunity for conducting further studies.

  13. A Global Integration: Internationalizing a Public Speaking Course

    Science.gov (United States)

    Lyons, Florence A.

    2017-01-01

    Institutions of higher education around the world have responded to the challenge of globalization by internationalizing their curricula. Incorporating elements of cross-cultural examination to a freshman Fundamentals of Public Speaking class proved to be an important first step toward globalization for this speech professor. In the class,…

  14. Internationalization of Higher Education: Implications for Policy Making

    Science.gov (United States)

    Wadhwa, Rashim; Jha, Shashiranjan

    2014-01-01

    During the last decade education worldwide has experienced massive changes ranging from domestic market inauguration to the internationalization. In due course of time, there has been a great urge for restructuring the education system to make it internationally comparable ensuring economic benefit. The developed countries have dominated through…

  15. The internationalization of Japan

    International Nuclear Information System (INIS)

    Kuroki, T.E.

    1989-01-01

    There are growing tensions and frictions between the U.S. and Japan. Among them are science and technology issues that relate to the development of superconductor technology, as well as economic, trade and agricultural issues. The structure of this friction is very complex. There are many interconnected issues that cannot be resolved one by one. This article focuses on the relationship between the U.S. and Japan. Some of the complexities behind the issues are discussed by defining different notions of internationalization and by presenting the positive and negative aspects of the Japanese approach that affects the future cooperation and competition between our nations in the area of superconductivity

  16. TENDENCIES OF INTERNATIONALIZATION IN RETAILING

    Directory of Open Access Journals (Sweden)

    Pop Nicolae Alexandru

    2008-05-01

    Full Text Available Manufacturing companies took advantage of internationalization as early as in the seventies and eighties of the last century, whereas retail companies have used these chances not before the last few years in order to improve access to resources, to increase sales and to extend activities to external markets. Once a retail company has decided to penetrate a foreign market they must be aware of the unfamiliar working of external environment that they cannot control. Even the world’s leading retailers make mistakes when approaching markets they do not understand properly.

  17. Factor VII assay

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/003676.htm Factor VII assay To use the sharing features on ... M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health ...

  18. The Role of Innovation in Internationalization of Brazilian Medium Firms that operate in Information Technology and Communication

    Directory of Open Access Journals (Sweden)

    Fernanda Ferreira Ribeiro

    2011-06-01

    Full Text Available The study aimed to examine the role of innovation in the internationalization of Brazilian companies that operate in the medium sector of Information and Communication Technology (ICT. To achieve this goal, we performed a descriptive qualitative research method used and how the study of multiple cases, which were researched in depth and Light Infocon and Dígitro. The main results of the survey revealed companies with different trajectories of internationalization, but whose innovation activities are central to the entry and operations in foreign markets. The results also showed the importance of innovative cooperative activities through alliances with universities, research institutes and other companies, and government support through funding. An additional contribution of this work was the analysis of the internationalization process of Brazilian companies innovative medium-sized sectors with high technological content, since most studies on internationalization in Brazil focuses on large industrial enterprises already established for decades in the national and sectors with low technological intensity.

  19. How Do We Capture "Global Specialization" When Measuring Firms' Degree of Internationalization?

    DEFF Research Database (Denmark)

    Geisler Asmussen, Christian; Pedersen, Torben; Petersen, Bent

    The IB literature informs us of several ways to measure firms' degree of internationalization. In this paper we make the argument that in fact none of the existing indices really measure firms' degree of "global specialization", that is, to what extent their allocation of resources is multidomestic...... or global. As argued, all the existing measures may gauge a purely multidomestic firm as having a high degree of internationalization, whereas a truly global firm may be ranked low. In order to remedy this we introduce a complementary index measuring how firms are configuring their value chains - whether...

  20. THE INTERNATIONALIZATION PROCESS OF THE SALES OPERATIONS OF THE PRODUCTS OF A SANITARY WARE INDUSTRY

    Directory of Open Access Journals (Sweden)

    Emerson Antonio Maccari

    2010-11-01

    Full Text Available Internationalization consists of extending an organization's operations abroad. It involves decisions based on objective criteria and on an evaluation of strategies for entering the foreign market. The problem addressed in this study concerns a Brazilian firm’s difficulties developing its operations abroad. Thus, the purpose of this study was to identify the internationalization process of an industry in the sanitary ware segment in the development of its operations in another country. The research method employed was the single case study and data was collected by means of a semi-structured research script applied to company executives. The results showed that the internationalization process is characterized by the dynamic learning model (Uppsala Model, according to which an organization develops its activities abroad gradually, as it acquires experience and expertise in the market. The company is attempting to overcome cultural barriers and psychic distance in a slow internationalization process, aligned with the differentiation strategy and focus that it uses in the Brazilian market. This strategy comprises a sequence of planned and deliberate steps, with low investment exposure and risk. It was found that the firm adopts a strategy of exporting through distributors, this being a critical success factor, but that the distributor approval and development process lacks robust and formalized structuring. There are opportunities for improvement in the process of competitive intelligence in order to systematize the search and interpretation of information about the markets in which the company wants to operate.  Key-words: Internationalization of companies. Uppsala Model. Strategy. Competitive intelligence. 

  1. THE PROCESS OF INTERNATIONALIZATION OF BRAZILIAN FIRMS: STUDY WITH FRANCHISORS

    Directory of Open Access Journals (Sweden)

    Daniela Motta Romeiro Khauaja

    2012-01-01

    Full Text Available The purpose of this study is to analyze the process of internationalization of Brazilian firms, including the motivations for the internationalization, the modes of entry and the difficulties faced during this process. This research is relevant due to the importance of international management for Brazilian firms at the current global scenario. Firstly, it was developed a theoretical basis and, afterwards, an empirical qualitative and exploratory research was carried out. The data were collected from in depth interviews with the representatives of ten Brazilian franchisors that became international, which are associated to the Brazilian Association of Franchising (ABF, who gave support to the research. The analytical procedure adopted was the content analysis. Franchising was chosen because Brazil is one of the most developed countries in this field and franchising is recognized as an important booster of the globalization process. The interviews were conducted with either the owner of the firm or the marketing or international executive officers. The results of the empirical research show that, although Brazilian firms are late movers, the firms analyzed do not seem handicapped in terms of managerial capacity or technological competences. It is clear, nevertheless, that they are late movers because they have a huge internal market to explore. Adopting a global vision is very important, even if they prefer a gradual approach towards internationalization.

  2. Internationalization of traditional Chinese medicine: current international market, internationalization challenges and prospective suggestions.

    Science.gov (United States)

    Lin, Annie Xianghong; Chan, Ging; Hu, Yuanjia; Ouyang, Defang; Ung, Carolina Oi Lam; Shi, Luwen; Hu, Hao

    2018-01-01

    Through reviewing the current international market for traditional Chinese medicine (TCM), this paper identified the internationalization challenges for TCM, including unclear therapeutic material basis and mechanism, difficulty of quality control, low preparation level, registration/policy barriers, and shortage of intellectual property. To deal with these challenges, suggestions were given including: (1) product innovation of TCM (study the TCM by using the methods and means of western medicine; innovate the basic theory of TCM; develop TCM health product); (2) standard innovation of TCM; (3) building big data platform of Chinese medicine (big data platform of TCM preparation; big data platform on the quality of TCM).

  3. The route of ´The sitting woman´. The cartoons of Copi between Paris and Buenos Aires

    Directory of Open Access Journals (Sweden)

    Isabel Plante

    2012-08-01

    Full Text Available During the 1960’ –those years marked by the growth of cultural industry and political radicalization in diverse points of the world–  the cultural field was shaped by the tensions between ‘Art’ and ‘minor culture’ or between visual production and political commitment. In this context, the multiple activity of Copi makes him a key case since it fluently traveled trough narrative writing, dramaturgy and graphic humor. Living in Paris since 1962, Copi created for the newspaper Le Nouvel Observateur the character that made this argentine artist famous in France, La Femme Assise (The sitting woman. Conceived for the massive audience of the modernized press of the 1960’, his strips questioned –with corrosive nonsense– middle sectors in expansion at both sides of the Atlantic Ocean. This paper tackles precisely with this sort of geographic and linguistic swinging mediated by Copi’s foreignness. This without eluding nor the graphic humor’s specificities, nor larger cultural phenomenon of the 1960’s like the internationalization of the urban culture and the fading of the borders of the artistic fields.

  4. The internationalization of the firm in an intercultural perspective

    DEFF Research Database (Denmark)

    Langhoff, Tine

    1993-01-01

    Executive summary: 1. Cultural heterogeneity is a major problem faced by companies wishing to internationalize in the food industry. In spite of this, the problems created by cultural diversity and the way companies solve them by acquiring intercultural competence have hardly been addressed...

  5. Climate Justice and the Paris Agreement

    International Nuclear Information System (INIS)

    Michelot, Agnes

    2016-01-01

    The concept of climate justice has been, for the first time, used in an international agreement - namely, the Paris Agreement. But this recognition of the notion of climate justice is extremely restricted by the very way it is formulated. Preamble of the Paris Agreement 'notes' that climate justice is recognized by 'certain cultures'. Does it mean that particular and concrete stakes of climate justice of the pre-COP21 agenda have been recognized or, on the contrary, that the notion so introduced is actually an empty shell without any genuine legal perspective? Considering this uncertainty, it appears relevant to analyze the Paris Agreement through the claims of various groups and coalitions, which influenced the COP21 negotiations

  6. Increased volume of distribution for recombinant activated factor VII and longer plasma-derived factor VII half-life may explain their long lasting prophylactic effect

    NARCIS (Netherlands)

    Mathijssen, N.C.J.; Masereeuw, R.; Holme, P.A.; Kraaij, M.G.J. van; Laros, B.A.P.; Peyvandi, F.; Heerde, W.L. van

    2013-01-01

    INTRODUCTION: Prophylaxis with plasma-derived or recombinant activated factor VII is beneficial in severe factor VII deficiency. To understand why prophylactic treatment with both products is efficacious, we conducted a pharmacokinetic study. MATERIALS AND METHODS: Ten factor VII deficient patients

  7. Internationalization of Higher Education: Potential Benefits and Costs

    Science.gov (United States)

    Jibeen, Tahira; Khan, Masha Asad

    2015-01-01

    Internationalization of higher education is the top stage of international relations among universities and it is no longer regarded as a goal in itself, but as a means to improve the quality of education. The knowledge translation and acquisition, mobilization of talent in support of global research and enchantment of the curriculum with…

  8. The myth of the stay-at-home family firm : How family-managed SMEs can overcome their internationalization limitations

    NARCIS (Netherlands)

    Hennart, Jean-Francois; Majocchi, A.; Forlani, E.

    The prevalent view among family-firm internationalization scholars is that family management discourages internationalization. This is because selling abroad is said to require more specialized managers and more resources than selling at home, and yet family firms are unwilling to recruit non-family

  9. Growth through internationalization : an online perspective on Born Globals

    NARCIS (Netherlands)

    Dennis Nevels

    2013-01-01

    Summary: The traditional landscape in international business has changed, for decades the Uppsala model of internationalization has been key-instrument for foreign success. Since McKinsey (1993) made notice of the term Born Global times have changed. More rapidly and in increasing numbers throughout

  10. Recombinant activated factor VII in cardiac surgery: single-center experience.

    Science.gov (United States)

    Singh, Sarvesh Pal; Chauhan, Sandeep; Choudhury, Minati; Malik, Vishwas; Choudhary, Shiv Kumar

    2014-02-01

    The widespread off-label use of recombinant activated factor VII for the control of refractory postoperative hemorrhage continues despite a warning from the Food and Drug Administration. Although effective in reducing the need for transfusion of blood and blood products, safety concerns still prevail. To compare the dosing and efficacy of recombinant activated factor VII between pediatric and adult patients, and in the operating room and intensive care unit. The records of 69 patients (33 children and 36 adults) who underwent cardiovascular surgery and received recombinant activated factor VII were reviewed retrospectively. The dose of recombinant activated factor VII, mediastinal drainage, use of blood and blood products, incidence of thrombosis, and 28-day mortality were studied. the efficacy of recombinant activated factor VII was comparable in adults and children, despite the lower dose in adults. Prophylactic use of recombinant activated factor VII decreased the incidence of mediastinal exploration and the duration of intensive care unit stay. A 4.3% incidence of thrombotic complications was observed in this study. The efficacious dose of recombinant activated factor VII is much less in adults compared to children. Prophylactic use of recombinant activated factor VII decreases the dose required, the incidence of mediastinal exploration, and intensive care unit stay, with no survival benefit.

  11. How much we know about university internationalization and university autonomy

    DEFF Research Database (Denmark)

    Turcan, Romeo V.; Gullieva, Valeria

    2013-01-01

    in their mission statements and strategic plans. Conventional wisdom suggests that universities should adapt their strategies, resources, and structures and organizations to international environments. However, recent examples of university internationalization failures and withdrawals from international markets...

  12. What agreement in Paris in 2015?

    International Nuclear Information System (INIS)

    Colombier, Michel; Ribera, Teresa

    2015-01-01

    In Warsaw, countries agreed to a process whereby each will unilaterally design and communicate its contribution toward reducing greenhouse gas emissions in the atmosphere. This process is to be ratified in late 2015 in Paris. Will the Paris agreement mark a turning point in climate policy? Will it measure up to the ambitions proclaimed by the international community at the Durban meeting?

  13. Why Is Family Firms' Internationalization Unique? : A Meta-Analysis

    NARCIS (Netherlands)

    Arregle, Jean-Luc; Duran, Patricio; Hitt, Michael A.; van Essen, M.

    Despite its importance, there is no clear understanding of the uniqueness of family firms' internationalization. This article sheds new light on this issue with a meta-analysis of 76 studies covering 41 countries. We show that the considerable study and cross-country differences in the relationship

  14. Case studies in the retailer internationalization: a literature review

    Directory of Open Access Journals (Sweden)

    Renata Maria de Almeida Bastos Gomes

    2017-04-01

    Full Text Available Research on retail internationalization (RI has undergone an intense development phase since the 1990s, dominated by quantitative research and based on the retail experience of large-scale retailers formats such as supermarkets. However, the internationalization of the retail sector has evolved into areas that existing models have not been able to explain, generating a demand for more thorough research. The result has been an increase of articles published since the early 2000s based on research of an exploratory and qualitative nature, such as case studies. In this article, main contributions are identified in RI arising from case studies resulting from the selection and analysis of 48 articles published in academic journals between 2000 and 2015. As a result, relevant findings on the steps of the RI process are presented, such as input modes for franchise, international divestment, and characteristics of the RI process of specific types of firms, such as fashion retailers and small- and medium-size retailers.

  15. Value, What Value? University Business Model in Pursuit of Advanced Internationalization

    DEFF Research Database (Denmark)

    Juho, Anita; Turcan, Romeo V.

    Through business model theoretical lenses, we explore in this paper issues and challenges universities face in their pursuit of advanced internationalization entries into foreign markets. The context of this paper is defined by universities from developed countries entering developing or emerging...... countries via foreign direct investment entry modes, such as joint ventures, acquisitions, green field or brown field investments. This is a theoretical paper. We draw on a number of sources of data to conceptualise issues and challenges universities face in their pursuit of advanced internationalization...... entries into foreign markets. First, we build on university autonomy, international business and business model theories to conceptualise the phenomenon of interest. Second, we analyse publicly available data, anecdotal evidence where the phenomenon we study is explicitly observable. The above theoretical...

  16. Proposed plan for a JAEA internationalization initiative (JII) (Contract research)

    Energy Technology Data Exchange (ETDEWEB)

    Bolton, Paul R; Kawanishi, Shunichi [Japan Atomic Energy Agency, Photo-Medical Research Center, Kizugawa, Kyoto (Japan); Mizuki, Jun' ichiro [Japan Atomic Energy Agency, Quantum Beam Science Directorate, Sayo, Hyogo (Japan)

    2011-01-15

    Concepts for a JAEA Internationalization Initiative, JII are presented. Following a general discussion of issues and recommendations for JII, a 'fast startup JII' is proposed in the form of fast start action items (FSAI). The FSAI represent a clear set of action items that can be implemented at the KPSI/PMRC site which would serve as a seed site for test and evaluation. A JAEA Internationalization Initiative that is guided by evaluation and tailored for JAEA as a whole can be established with appropriate oversight and tracking at each JAEA site by local JII teams. In addition to recommendations for the KPSI/PMRC seed site, the roles of the Quantum Beam Science Directorate (QuBS) leadership and the International Affairs Department (IAD) of JAEA are also discussed. Current KPSI/PMRC activities that are consistent with a JII are briefly presented. (author)

  17. Proposed plan for a JAEA internationalization initiative (JII) (Contract research)

    International Nuclear Information System (INIS)

    Bolton, Paul R.; Kawanishi, Shunichi; Mizuki, Jun'ichiro

    2011-01-01

    Concepts for a JAEA Internationalization Initiative, JII are presented. Following a general discussion of issues and recommendations for JII, a 'fast startup JII' is proposed in the form of fast start action items (FSAI). The FSAI represent a clear set of action items that can be implemented at the KPSI/PMRC site which would serve as a seed site for test and evaluation. A JAEA Internationalization Initiative that is guided by evaluation and tailored for JAEA as a whole can be established with appropriate oversight and tracking at each JAEA site by local JII teams. In addition to recommendations for the KPSI/PMRC seed site, the roles of the Quantum Beam Science Directorate (QuBS) leadership and the International Affairs Department (IAD) of JAEA are also discussed. Current KPSI/PMRC activities that are consistent with a JII are briefly presented. (author)

  18. The impact of internationalization and diversification on construction industry performance

    NARCIS (Netherlands)

    Horta, Isabel M.; Kapelko, Magdalena; Oude Lansink, Alfons; Camanho, Ana S.

    2016-01-01

    This paper investigates the impact of internationalization and diversification strategies on the financial performance of construction industry companies. The results obtained can guide the design of strategies to pursue company growth and achieve competitive advantage. The evaluation of

  19. 77 FR 64400 - Order of Succession for HUD Region VII

    Science.gov (United States)

    2012-10-19

    ... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [FR-5550-D-10] Order of Succession for HUD Region VII... Offices (Region VII). This Order of Succession supersedes all previous Orders of Succession for HUD Region...). This publication supersedes all previous Orders of Succession for Region VII. Accordingly, the...

  20. Report of Committee for JAEA Internationalization Initiative

    International Nuclear Information System (INIS)

    2013-03-01

    In global circumstances surrounding nuclear energy, the role expected to Japan Atomic Energy Agency (JAEA) is becoming increasingly important. JAEA has been promoted an initiative for the international hub in order to increase the scientific competitiveness of Japan and make international contributions, by gathering excellent researchers from the entire world with the latest facilities. Also, JAEA established 'Committee for JAEA Internationalization Initiative', which will discuss issues such as environmental improvement for accepted foreigners, direction of efforts for internationalization initiative and strategies to improve current situation. This report mentions the results of the committee's discussion including current issues for the initiative and recommendations for their solution, as well as the issues to be discussed in order to enhance international awareness of JAEA staff. The following is the summary of the recommendations for the initiative: Set up local teams that focus on the situation of each site in order to provide detailed support for foreigners from diversified backgrounds. Develop systems for emergency situations to provide information for safety swiftly for foreigners and confirm their safety, in addition to preparing emergency goods. Prepare bilingual documents and systems that foreigners need to use for their work based on importance and frequency of use of such systems and documents. (author)

  1. Internationalization Strategies for Multinational Companies (MNCs) : In the case of KWH Mirka Oy to Ethiopia

    OpenAIRE

    Yigzaw, Tamirat

    2015-01-01

    This thesis is done for the fulfilment of Masters of Business Administration (MBA) degree program in Business Management and Entrepreneurship at Häme University of Applied Sciences (HAMK). The main focus of the study is internationalization of companies to a new market as a development task for the company. The commissioner of the thesis is Mirka Oy, a Finnish multinational company. The purpose of the thesis was to study factors that should be considered in internationalization strategies...

  2. Multinational Enterprises from Small Economies: The Internationalization Pattern of Large Companies from Denmark, Finland and Norway

    OpenAIRE

    Benito, Gabriel R.G.; Larimo, Jorma; Narula, Rajneesh; Pedersen, Torben

    2001-01-01

    Analyzing the internationalization of large companies from small countries requires understanding the process of internationalization by examining the interface between micro (firm strategies) and macro (the forces of centripetal and centrifugal) level factors. We examine the growth and international expansion of the ten largest companies in Denmark, Finland, and Norway over the period 1990 to 1999. Most companies in the sample became more international during the last decade across basically...

  3. Internationalizing Business Education in Latin America: Issues and Challenges

    Science.gov (United States)

    Elahee, Mohammad; Norbis, Mario

    2009-01-01

    This article examines the extent of internationalization of business education in Latin America and identifies the key challenges facing the Latin American business schools. Based on a survey of the business schools that are members of CLADEA (Consejo Latinoamericano de Escuelas de Administracion--Latin American Council of Management Schools), and…

  4. Internationalization of SMES: business opportunities in Chile

    OpenAIRE

    Correia, João Filipe Amado

    2016-01-01

    The main goal of this study is to identify the main business opportunities in Chile, legal advantages in the business perspective and entry strategies for small and medium sized enterprises (SMEs). The methodology used was qualitative, by conducting several interviews with chamber of commerce representative from Portugal in Chile and Chile in Portugal, several young entrepreneurs from different nations operating in Chile, the CEO of a Spanish company that decided to not internationalize to...

  5. Frederik VII og folkets kærlighed

    DEFF Research Database (Denmark)

    Perlt, Michael; Vinding, Niels Valdemar

    2013-01-01

    I den turbulente tid mellem de to slesvigske krige drog kong Frederik VII under en rejse til Jylland i 1857 i procession op på højene i Jelling for at modtage folkets hyldest. På det historiske sted lod Frederik VII sig fejre som danskernes konge under en stor folkefest med bønder og deres familier...

  6. THE INTERNATIONALIZATION OF JBS AND A DISCUSSION OF PORTER´S DIAMOND

    Directory of Open Access Journals (Sweden)

    Carlos Honorato Teixeira

    2010-08-01

    Full Text Available This paper aims to discuss the theories of internationalization and competitiveness, the positioning of a Brazilian company from agribusiness industry, exporting meat and food that has become a major global player in this industry JBS - Friboi. This company has been internationalized very fast in recent years and become a global leader in beef production, the second to the production of chicken meat and third largest producer of pork in the U.S. (JBS, 2010. The case is emblematic of JBS when analyzed under the concept of Porter's diamond applied to Brazil. This company gained scale and competitiveness with the access to natural resources of prodution (condition factor, but now it is necessary for maintenance its leading position, it requires a strategy grounded in innovation beyond just scale and operational excellence.

  7. Verification OFENDF/B-VII.0, ENDF/B-VII.1 and JENDL-4.0 nuclear data libraries for criticality calculations using NEA/NSC benchmarks

    International Nuclear Information System (INIS)

    Bouhaddane, A.; Farkas, G.; Hascik, J.; Slugen, V.

    2015-01-01

    The paper presents verification of selected nuclear data libraries with the aim to apply them to fast reactor calculations. More precise results were achieved for thermal neutrons calculations. This corresponds with the demand for more precise nuclear data for fast reactors. However, fast neutron calculations show some consistency, in particular between ENDF-B/VII.1 and JENDL-4.0 nuclear data libraries. The results support the idea to prefer using newer ENDF-B/VII.1 instead of the previous version ENDF-B/VII.0. Certainly, there are still some issues to be addressed and there is potential to gain more conclusive results. Although, application of ENDF-B/VII.1 and JENDL-4.0 is expected for further calculations. (authors)

  8. Preparation of factor VII concentrate using CNBr-activated Sepharose 4B immunoaffinity chromatography.

    Science.gov (United States)

    Mousavi Hosseini, Kamran; Nasiri, Saleh

    2015-01-01

    Factor VII concentrates are used in patients with congenital or acquired factor VII deficiency or treatment of hemophilia patients with inhibitors. In this research, immunoaffinity chromatography was used to purify factor VII from prothrombin complex (Prothrombin- Proconvertin-Stuart Factor-Antihemophilic Factor B or PPSB) which contains coagulation factors II, VII, IX and X. The aim of this study was to improve purity, safety and tolerability as a highly purified factor VII concentrate. PPSB was prepared using DEAE-Sephadex and was used as the starting material for purification of coagulation factor VII. Prothrombin complex was treated by solvent/detergent at 24°C for 6 h with constant stirring. The mixture of PPSB in the PBS buffer was filtered and then chromatographed using CNBr-activated Sepharose 4B coupled with specific antibody. Factors II, IX, VII, X and VIIa were assayed on the fractions. Fractions of 48-50 were pooled and lyophilized as a factor VII concentrate. Agarose gel electrophoresis was performed and Tween 80 was measured in the factor VII concentrate. Specific activity of factor VII concentrate increased from 0.16 to 55.6 with a purificationfold of 347.5 and the amount of activated factor VII (FVIIa) was found higher than PPSB (4.4-fold). RESULTS of electrophoresis on agarose gel indicated higher purity of Factor VII compared to PPSB; these finding revealed that factor VII migrated as alpha-2 proteins. In order to improve viral safety, solvent-detergent treatment was applied prior to further purification and nearly complete elimination of tween 80 (2 μg/ml). It was concluded that immuonoaffinity chromatography using CNBr-activated Sepharose 4B can be a suitable choice for large-scale production of factor VII concentrate with higher purity, safety and activated factor VII.

  9. Dominated by Economics? Evidence of Changing Drivers of Internationalization and Its Funding within Higher Education Institutions in Europe

    Science.gov (United States)

    Hudson, Ross

    2016-01-01

    As internationalization has become an increasingly central part of higher education (HE), the range and types of activities carried out in its name have grown exponentially. At the same time, and particularly in the context of reduced public funding for HE in some countries, internationalization and its related activities have come to be seen as…

  10. Internationalization Assessment in Schools: Theoretical Contributions and Practical Implications

    Science.gov (United States)

    Yemini, Miri

    2012-01-01

    Cosmopolitan, international capital has become an integral ingredient in the set of competencies considered to provide a competitive edge and to be required for affective citizenship in the 21st century. Recently, internationalization of education has become a more common phenomenon in local schools around the world, serving as a tool to provide…

  11. Is prophylaxis required for delivery in women with factor VII deficiency?

    Science.gov (United States)

    Baumann Kreuziger, L M; Morton, Colleen T; Reding, Mark T

    2013-11-01

    Factor VII (fVII) deficiency is a rare congenital bleeding disorder in which fVII activity level and bleeding tendency do not completely correlate. Pregnancy and delivery present a significant haemostatic challenge to women with fVII deficiency. Treatment with recombinant factor VIIa (rfVIIa) carries a thrombotic risk and the literature is not clear whether prophylaxis is necessary prior to delivery. The aim of this study was to define management, haemorrhagic and thrombotic complications of pregnant women with fVII deficiency through a systematic review. Medical databases (PubMed, MEDLINE, CINAHL, Academic Search Premier, Cochrane Library, Web of Science and Scopus) were searched using "factor VII deficiency" and "pregnancy" or "surgery." Overall 34 articles, four abstracts, and three institutional cases were reviewed. Literature from 1953 to 2011 reported 94 live births from 62 women with fVII deficiency. The median fVII activity was 5.5%. Haemostatic prophylaxis was used in 32% of deliveries. Without prophylaxis, 40 vaginal deliveries and 16 caesarean sections were completed. The odds of receiving prophylaxis were 2.9 times higher in women undergoing caesarean section compared to vaginal delivery. Post-partum haemorrhage occurred in 10% of deliveries with prophylaxis and 13% of deliveries without prophylaxis. The fVII level did not significantly differ between women who did and did not receive prophylaxis. We present the only systematic review of the management of pregnancy in fVII deficient women. No difference in post-partum haemorrhage was seen in deliveries with and without prophylaxis. Therefore, we recommend that rfVIIa be available in the case of haemorrhage or surgical intervention, but not as mandatory prophylaxis. © 2013 John Wiley & Sons Ltd.

  12. [Coagulation factor VII levels in uremic patients and theirs influence factors].

    Science.gov (United States)

    Fang, Jun; Xia, Ling-Hui; Wei, Wen-Ning; Song, Shan-Jun

    2004-12-01

    This study was aimed to investigate coagulation factor VII level in uremic patients with chronic renal failure and to explore theirs influence factors. The plasma levels of coagulation factor VII were detected in 30 uremic patients with chronic renal failure before and after hemodialysis for 1 month, the factor VII activity (FVII:C) was determined by one-stage coagulation method, while activated factor VII (FVIIa) was measured by one-stage coagulation method using recombinant soluble tissue factor, and factor VII antigen was detected by ELISA. The results showed that: (1) The FVIIa, FVII:C and FVIIAg levels in chronic uremic patients before hemodialysis were 4.00 +/- 0.86 microg/L, (148.5 +/- 40.4)% and (99.8 +/- 21.1)% respectively, which were significantly increased, as compared with healthy controls [2.77 +/- 1.02 microg/L, (113.1 +/- 33.0)% and (73.7 +/- 18.3)% respectively, P factor VII was positively correlated with levels of blood uria nitrogen and serum creatinine before hemodialysis but not after hemodialysis. It is concluded that the enhanced levels of coagulation factor VII in chronic uremic patients suggested abnormal activated state, herperactivity and elevated production of factor VII which correlated with renal functional injury. The abnormality of factor VII in uremia may be aggravated by hemodialysis. Coagulation factor (FVII) may be a risk factor for cardiovascular events in uremic patients who especially had been accepted long-term hemodialysis.

  13. Equality, reasonableness and gender in the process of constitutionalization and internationalization of law

    Directory of Open Access Journals (Sweden)

    Manuel Fernando Quinche-Ramírez

    2012-06-01

    Full Text Available The themes of this paper are equality, reasonableness and gender rights in the dynamics of two sequential and convergent processes: the constitutionalization of judicial law, and the internationalization of constitutional law. The thesis of this paper is that in the face of non-compliance of the obligation to regulate, guarantee and protect gender rights, the best option has been to strengthen judicial law, which has enabled the development of rules for protection, the adoption of contemporary methods of interpretation and adjudication of the law, as well as the resolution of shortfalls in protection based on said processes of the constitutionalization and internationalization of local law.

  14. Paris Commune Imagery in China's Mass Media.

    Science.gov (United States)

    Meiss, Guy T.

    The role of ideology in mass media practices is explored in an analysis of the relation between the Paris Commune of 1871 and the Shanghai Commune of 1967, two attempts to translate the philosophical concept of dictatorship of the proletariat into some political form. A review of the use of Paris Commune imagery by the Chinese to mobilize the…

  15. EFFECTIVE INDICATORS FOR SCIENCE INTERNATIONALIZATION.

    Science.gov (United States)

    Cunha-Melo, José Renan da

    2015-01-01

    To review of concepts and actions that aim to analyze the effects of internationalization of science and education, with emphasis in the medical field and its basement in development policies adopted by nations, exploring the potential for international interdisciplinary cooperation of each laboratory, department, university or institute. Search of indicators to assess the degree of internationalization of universities and research institutes in several interconnected levels: organizational, regional, sectoral and global, and policy-making in science, technology innovation and higher education. Scientific research is still carried out individually, but is now much more closely integrated with other social processes. The scientist is no longer a stranger who is allowed to surrender to his hobby to do what it wants. Internationalization of research and medical education, although it is among the topics of greatest need, as the globalized world, is difficult activity to be assessed. The leaders seem to have understood that the knowledge societies, leading to economic policy based on knowledge, can result in economic and social progress of nations. This fact has motivated increasingly the incentive to actions aimed at addressing global problems (eg health, climate change) by funding research that generates new knowledge. The consensus is that the internationalization of science is desirable and necessary for the sustainable development of nations. However it cannot be done only by encouraging and promoting the outward students and researchers abroad. It is necessary, in addition, offer conditions to foreign researchers and students teachers to work in collaboration with Brazilian and raise the country to international scientific standards. Apresentar revisão dos conceitos e ações que objetivam analisar os efeitos da internacionalização da ciência e da educação, com ênfase na área médica e seu embasamento nas políticas de desenvolvimento adotadas pelas na

  16. Morphological diversity of wild medicinal Paris L. from China and ...

    African Journals Online (AJOL)

    Paris L. (Trilliaceae) is a temperate genus of about 24 perennial herbaceous species distributed from Europe to Eastern Asia. Paris is notable in China for its medicinal value. An investigation was conducted to determine the variations of 27 morphological characters of 196 accessions from 8 populations of medicinal Paris ...

  17. Políticas públicas e internacionalização de empresas brasileiras / Public policy and internationalization of brazilian enterprises

    Directory of Open Access Journals (Sweden)

    Leandro Bruno Santos

    2015-04-01

    Full Text Available The productive internationalization is an essential process to the enterprises strengthening and nations competitiveness growing, due to positive impact on their flows, technology and foreign exchange trade. The major developed economies were pioneers in supporting their enterprises trade and productive internationalization, by creation of funding programs, market research, insurance and guarantees, and trade missions. The objective of this text is to analyze the Brazilian State role played in the several cycles of local companies productive internationalization on the one hand and display in detail the more decisive role of the Banco Nacional de Desenvolvimento Econômico e Social (BNDES in the “national champions” formation and productive internationalization during the early years of this century on the other. The main conclusion is that the bank, to support groups that operate in capital and natural resources intensive industries, has reinforced the regressive specializations and the adaptation technological pattern.

  18. Internationalization path to the United Arab Emirates

    OpenAIRE

    Räsänen, Paula

    2010-01-01

    The purpose of the thesis was to introduce internationalization of an SME including motives and risks of new market entry, as well as describing the steps of a target market selection and presenting different operational modes. Since the executive company, DesignShopOutlet, was interested in exploring their market possibilities in the United Arab Emirates, the aim of the thesis was also to conduct a market research report of the United Arab Emirates. The study applied a qualitative resea...

  19. Extended analyses of Se VII and Se VIII

    International Nuclear Information System (INIS)

    Vankleef, Th.A.M.; Joshi, Y.N.

    1984-01-01

    Joshi et al. (1984) have conducted an analysis of the 3d8 4s-3d8 4p transitions in As VII. The present investigation is concerned with an analysis of similar transitions in Se VIII. The selenium spectrum was photographed in the 400-1200-A wavelength region on a variety of normal-incidence spectrographs. Attention is given to least-squares-fit (LSF) and Hartree-Fock (HF) parameter values for the 3d9 4d configuration of Se VII, LSF and HF parameter values for the 3d8 4s and 3d8 4p configurations of Se VIII, the energy and composition of the levels of the 3d9 4d configuration of Se VII, classified lines in Se VII, energy levels and composition of the 3d8 4s configuration and the revised and newly determined levels of the 3d8 4p configuration of Se VIII, and newly classified lines of Se VIII. 15 references

  20. INTERNATIONALIZATION ON THE SUGAR-ALCOHOL SECTOR IN THE NORTHEAST

    Directory of Open Access Journals (Sweden)

    Edjackson Marques Ferreira

    2010-12-01

    Full Text Available The purpose of the present work is to analyze how companies on the sugar- alcohol sector in the Northeast are internationalizing their production. Six theories were selected to guide the analyses undertaken: Life Cicle, Uppsala, Adaptive Choice, Eclectic Paradigm, Resourcebased View and Diamond Model. The research strategy was the case study and the data was gathered through sectorial documents and semi-structured interviews. The Atlas/ti software aided the data analysis. As a result, evidence was made that there is a strong and decisive presence of location and internal resources aspects, underlined in the Diamond Model, the Eclectic Paradigm and the Resource-based View as fundamental in the internationalization of the activities of companies from Paraiba. The formation of a strong internal network, adopted by the Network Theory, also showed its importance. The other theories under analysis became less applicable, mainly due to the nature of the sugar-ethanol sector in Paraiba, which exports indirectly, and to the fact that their products are highly standardized.

  1. Age-related changes in factor VII proteolysis in vivo.

    Science.gov (United States)

    Ofosu, F A; Craven, S; Dewar, L; Anvari, N; Andrew, M; Blajchman, M A

    1996-08-01

    Previous studies have reported that pre-operative plasmas of patients over the age of 40 years who developed post-operative deep vein thrombosis (DVT) had approximately twice the amount of proteolysed factor VII found in plasmas of patients in whom prophylaxis with heparin or low M(r) heparin was successful. These and other studies also reported higher concentrations of thrombin-antithrombin III in pre- and post-operative plasmas of patients who developed post-operative thrombosis than in plasmas of patients in whom prophylaxis was successful. Whether the extent of factor VII proteolysis seen in the patients who developed post-operative DVT is related to the severity of their disease or age is not known. This report investigated age-related changes in the concentrations of total factor VII protein, factor VII zymogen, factor VIIa, tissue factor pathway inhibitor, thrombin-antithrombin III, and prothrombin fragment 1 + 2 in normal plasmas and the relationships between these parameters. With the exception of thrombin-antithrombin III, statistically significant increases in the concentrations of these parameters with age were found. Additionally, the differences between the concentrations of total factor VII protein and factor VII zymogen, an index factor VII proteolysis in vivo, were statistically significant only for individuals over age 40. Using linear regression analysis, a significant correlation was found to exist between the concentrations of plasma factor VIIa and prothrombin fragment 1 + 2. Since factor VIIa-tissue factor probably initiates coagulation in vivo, we hypothesize that the elevated plasma factor VIIa (reflecting a less tightly regulated tissue factor activity and therefore increased thrombin production in vivo) accounts for the high risk for post-operative thrombosis seen in individuals over the age of 40.

  2. A Disciplinary Perspective: The Internationalization of Australian Public Relations Education

    Science.gov (United States)

    Fitch, Kate

    2013-01-01

    This article investigates the internationalization of public relations education, by examining public relations education in Australia, its relation with the public relations industry, and its growth in response to international student- and market-led demand. The discussion highlights the tensions within what is essentially an education project…

  3. Market Channels of Technology Startups that Internationalize Rapidly from Inception

    Directory of Open Access Journals (Sweden)

    Simar Yoos

    2012-10-01

    Full Text Available The study of technology startups that internationalize rapidly from inception has increased in recent years. However, little is known about their channels to market. This article addresses a gap in the "born global" literature by examining the channels used by six startups that internationalized rapidly from inception as well as the programs they used to support their channel partners and customers. The six startups examined combined the use of the Internet with: i a relationship with a multi-national, ii distributors, iii re-sellers, or iv a direct sales force. They also delivered programs to support partners and customers that focused on communications, alliance and network development, education, marketing and promotion, and financial incentives. This article informs entrepreneurs who need to design go-to-market channels to exploit global opportunities about decisions made by other entrepreneurs who launched born-global companies. Normative rules and practitioner-oriented approaches are needed to help entrepreneurs explain and apply the results presented in this article.

  4. Life-threatening bleeding in a case of autoantibody-induced factor VII deficiency.

    Science.gov (United States)

    Okajima, K; Ishii, M

    1999-02-01

    A male patient presented with life-threatening bleeding induced by autoantibody-induced factor VII (F.VII) deficiency. This patient had macroscopic hematuria, skin ecchymosis, gastrointestinal bleeding, and a neck hematoma that was causing disturbed respiration. He developed acute renal failure and acute hepatic failure, probably due to obstruction of the ureters and the biliary tract, respectively. Although activated partial thromboplastin time was normal, prothrombin time (PT) was remarkably prolonged at 71.8 seconds compared to 14.0 seconds in a normal control. Both the immunoreactive level of F.VII antigen and the F.VII activity of the patient's plasma samples were VII activity. These findings suggested the presence of a plasma inhibitor for F.VII. After administration of large doses of methylprednisolone, PT was gradually shortened and plasma levels of F.VII increased over time. Bleeding, acute renal failure, and acute hepatic failure improved markedly following the steroid treatment. These observations suggest that life-threatening bleeding can be induced by autoantibody-induced F.VII deficiency and that immunosuppressive therapy using large doses of steroid can be successful in inhibiting the production of the autoantibody.

  5. The myriad challenges of the Paris Agreement

    Science.gov (United States)

    Mitchell, Dann; Allen, Myles R.; Hall, Jim W.; Muller, Benito; Rajamani, Lavanya; Le Quéré, Corinne

    2018-05-01

    The much awaited and intensely negotiated Paris Agreement was adopted on 12 December 2015 by the Parties to the United Nations Framework Convention on Climate Change. The agreement set out a more ambitious long-term temperature goal than many had anticipated, implying more stringent emissions reductions that have been under-explored by the research community. By its very nature a multidisciplinary challenge, filling the knowledge gap requires not only climate scientists, but the whole Earth system science community, as well as economists, engineers, lawyers, philosophers, politicians, emergency planners and others to step up. To kick start cross-disciplinary discussions, the University of Oxford's Environmental Change Institute focused its 25th anniversary conference upon meeting the challenges of the Paris Agreement for science and society. This theme issue consists of review papers, opinion pieces and original research from some of the presentations within that meeting, covering a wide range of issues underpinning the Paris Agreement. This article is part of the theme issue `The Paris Agreement: understanding the physical and social challenges for a warming world of 1.5°C above pre-industrial levels'.

  6. Acquired factor VII deficiency associated with acute myeloid leukemia.

    Science.gov (United States)

    Anoun, Soumaya; Lamchahab, Mouna; Oukkache, Bouchra; Qachouh, Maryam; Benchekroun, Said; Quessar, Asmaa

    2015-04-01

    Isolated acquired factor VII deficiency is a rare coagulopathy. It has been reported in 31 patients with malignancy, sepsis, postoperatively, aplastic anemia, and during bone marrow transplantation. We discuss, through a new case of acquired factor VII deficiency, the characteristics of this disease when it is associated with acute myeloid leukemia. Acquired factor VII deficiency in hematological diseases can be caused by intensive chemotherapy, infections, or hepatic dysfunction. The best treatment in developing countries remains corticosteroids associated with plasma exchange, frozen plasma, and antibiotics.

  7. Internationalization of Tertiary Education Services in Singapore

    OpenAIRE

    Mun-Heng Toh

    2012-01-01

    This paper traces the development of the education sector from its nascent stage of serving economic development needs to the internationalization stage of fulfilling Singapore’s aspiration to be a global education hub. The state plays an important role in guiding and fostering development of the education sector in the creation and production of human capital for domestic production as well as cross-border trading to generate income and employment, and attract talent to the economy. Reg...

  8. Internationalization of Higher Education: Preparing Faculty to Teach Cross-Culturally

    Science.gov (United States)

    Gopal, Anita

    2011-01-01

    The need to effectively prepare faculty to teach in a cross-cultural environment has become imperative in the context of globalizing higher education (Deardorff, 2009; Verbik, 2007). Many higher education institutions around the world have internationalized their degrees and programs, and they have established foreign branch campuses to provide…

  9. Preparation of factor VII concentrate using CNBr-activated Sepharose 4B immunoaffinity chromatography

    OpenAIRE

    Mousavi Hosseini, Kamran; Nasiri, Saleh

    2015-01-01

    Background: Factor VII concentrates are used in patients with congenital or acquired factor VII deficiency or treatment of hemophilia patients with inhibitors. In this research, immunoaffinity chromatography was used to purify factor VII from prothrombin complex (Prothrombin- Proconvertin-Stuart Factor-Antihemophilic Factor B or PPSB) which contains coagulation factors II, VII, IX and X. The aim of this study was to improve purity, safety and tolerability as a highly purified factor VII conce...

  10. Paris Convention on third party liability in the field of nuclear energy and Brussels Convention Supplementary to the Paris Convention

    International Nuclear Information System (INIS)

    1989-01-01

    This new bilingual (English and French) edition of the 1960 Paris Convention and 1963 Brussels Supplementary Convention incorporates the provisions of the Protocols which amended each of them on two occasions, in 1964 and 1982. The Expose des motifs to the Paris Convention, as revised in 1982 is also included in this pubication. (NEA) [fr

  11. MULTI-MARKET INDUSTRIAL ORGANIZATIONAL ECONOMIC MODELS FOR THE INTERNATIONALIZATION PROCESS BY SMALL AND MEDIUM ENTERPRISE CONSTRUCTION DESIGN SERVICE FIRMS

    Directory of Open Access Journals (Sweden)

    Kerry London

    2010-11-01

    Full Text Available Small and medium enterprises (SMEs are critical to strategic initiatives in an economy; however, their contribution to foreign trade is not as significant. SMEs are one of the principal driving forces in economic development. One of the greatest challenges is the internationalization process for longevity rather than seeing the process as initial market entry. The internationalization process research has typically involved four key constructs: market selection, decision to enter, entry modes and factors affecting entry modes. Past research has focused on large manufacturing firms. The export of architectural, engineering and construction (AEC firms has undergone growth, yet there is still significant opportunity for further growth. The majority of AEC firms are SMEs. Notwithstanding assistance provided through international trade missions, organized export firm support networks and information packages by a burgeoning number of government agencies, there are still perceived barriers to market entry and long-term economic sustainability for SMEs. There are a number of problems faced by SMEs acting in foreign trade. This investigation explores the successful initial internationalization process constructs and identifies unique project-oriented sector characteristics. The study identified similarities and differences between two firms that have been exporting to various localities, including Eastern Europe, Africa, Middle East, UK, Asia and South America, for more than two decades. The similarities and differences were identified within eight major constructs: purpose, firm type, market image and design philosophy, entry mode strategy, institutional arrangement, factors affecting mode of entry, market selection and firm strategy in relation to project selection. The primary reasons for internationalization were associated with the firms' motivations related to growth and financial viability. This article discusses the various internationalization

  12. Internationalization of portuguese luxury firms to emerging markets : Loja das Meias and Fátima Lopes case study

    OpenAIRE

    Carvalho, Madalena Maria Gema de

    2012-01-01

    In a fast evolving luxury industry, brands strive to grow and seek news ways to reach success. This thesis focuses on the internationalization of Portuguese luxury firms to emerging markets. Internationalization comes has a significant response to the fast-passing luxury industry, which alongside with limited room to evolve in the Portuguese luxury market, has driven national firms to widen their boarders and expand to international audiences. As emerging markets are increasingly showing thei...

  13. Characterization and Conditions of the Internationalization Process of Companies in the Plastic Products Manufacturing Subsector in Bogota

    Directory of Open Access Journals (Sweden)

    Jackson Paul Pereira Silva

    2016-04-01

    Full Text Available This paper proposes a qualitative research by conducting surveys in 30 companies from the plastic products manufacturing subsector, based on theories of internationalization. It aims to find the main determinants of internationalization of these companies, while characterizing and analyzing evidence by contrasting practice and theory, in order to explain how the dynamics in the sector and its current state are and to propose recommendations for greater competitiveness and efficiency in foreign trade.

  14. Factor VII-activating protease

    DEFF Research Database (Denmark)

    Ramanathan, Ramshanker; Gram, Jørgen B; Sand, Niels Peter R

    2017-01-01

    : Factor VII-activating protease (FSAP) may regulate development of cardiovascular disease (CVD). We evaluated sex differences in FSAP measures and examined the association between FSAP and coronary artery calcification (CAC) in a middle-aged population. Participants were randomly selected citizens...

  15. Universities' Expectations for Study-Abroad Programs Fostering Internationalization: Educational Policies

    Science.gov (United States)

    Take, Hiroko; Shoraku, Ai

    2018-01-01

    Because internationalization in higher education has recently received significant attention within the context of globalization, universities in Japan have begun to develop study-abroad programs to support their students in gaining international experience. This article explores those university policies designed to support the…

  16. Chinese immigrant entrepreneurs’ involvement in internationalization and innovation: Three Canadian cases

    DEFF Research Database (Denmark)

    Zhang, Xiaotian; Vissak, Tiia

    2014-01-01

    that these immigrants’ experience of doing business in China and Canada, their network relationships and knowledge of these markets quickened their firms’ internationalization considerably. Moreover, these firms became active in product or service innovation as the case immigrants also involved other immigrants...

  17. The role of interpretation in the internationalization of smaller brazilian firms

    NARCIS (Netherlands)

    R.W. Seifert (Ralf); J. Child (John); S.B. Rodrigues (Suzana)

    2012-01-01

    textabstractAbstract This study considers how decision-makers in smaller firms interpret the means and conditions of internationalization, and how different modes of interpretation are likely to inform action choices in this process. Drawing on 58 qualitative interviews with the leaders of

  18. Factor VII Deficiency: Clinical Phenotype, Genotype and Therapy.

    Science.gov (United States)

    Napolitano, Mariasanta; Siragusa, Sergio; Mariani, Guglielmo

    2017-03-28

    Factor VII deficiency is the most common among rare inherited autosomal recessive bleeding disorders, and is a chameleon disease due to the lack of a direct correlation between plasma levels of coagulation Factor VII and bleeding manifestations. Clinical phenotypes range from asymptomatic condition-even in homozygous subjects-to severe life-threatening bleedings (central nervous system, gastrointestinal bleeding). Prediction of bleeding risk is thus based on multiple parameters that challenge disease management. Spontaneous or surgical bleedings require accurate treatment schedules, and patients at high risk of severe hemorrhages may need prophylaxis from childhood onwards. The aim of the current review is to depict an updated summary of clinical phenotype, laboratory diagnosis, and treatment of inherited Factor VII deficiency.

  19. Internationalization Impact on PhD Training Policy in Russia: Insights from The Comparative Document Analysis

    Directory of Open Access Journals (Sweden)

    Oksana Chigisheva

    2017-09-01

    Full Text Available The relevance of the study is due to the need for an objective picture of the Russian third level tertiary education transformation driven by internationalization issues and global trends in education. The article provides an analytical comparative review of the official documents related to the main phases of education reform in Russia and focuses on the system of PhD training which has undergone significant reorganization in recent years. A series of alterations introduced into the theory and practice of postgraduate education in Russia are traced in regulatory documents and interpreted in terms of growing internationalization demand. Possible implications for further development of the research human potential in Russia are being discussed. The method of comparative document analysis produces the best possible insight into the subject. The findings of the study contribute to the understanding of current challenges facing the system of doctoral studies in Russia and lead to certain conclusions on the transformation of educational policy in relation to PhD training under the influence of internationalization agenda.

  20. PARIS reprograms glucose metabolism by HIF-1α induction in dopaminergic neurodegeneration.

    Science.gov (United States)

    Kang, Hojin; Jo, Areum; Kim, Hyein; Khang, Rin; Lee, Ji-Yeong; Kim, Hanna; Park, Chi-Hu; Choi, Jeong-Yun; Lee, Yunjong; Shin, Joo-Ho

    2018-01-22

    Our previous study found that PARIS (ZNF746) transcriptionally suppressed transketolase (TKT), a key enzyme in pentose phosphate pathway (PPP) in the substantia nigra (SN) of AAV-PARIS injected mice. In this study, we revealed that PARIS overexpression reprogrammed glucose metabolic pathway, leading to the increment of glycolytic proteins along with TKT reduction in the SN of AAV-PARIS injected mice. Knock-down of TKT in differentiated SH-SY5Y cells led to an increase of glycolytic enzymes and decrease of PPP-related enzymes whereas overexpression of TKT restored PARIS-mediated glucose metabolic shift, suggesting that glucose metabolic alteration by PARIS is TKT-dependent. Inhibition of PPP by either PARIS overexpression or TKT knock-down elevated the level of H 2 O 2 , and diminished NADPH and GSH levels, ultimately triggering the induction of HIF-1α, a master activator of glycolysis. In addition, TKT inhibition by stereotaxic injection of oxythiamine demonstrated slight decrement of dopaminergic neurons (DNs) in SN but not cortical neurons in the cortex, suggesting that TKT might be a survival factor of DNs. In differentiated SH-SY5Y, cell toxicity by GFP-PARIS was partially restored by introduction of Flag-TKT and siRNA-HIF-1α. We also observed the increase of HIF-1α and glycolytic hexokinase 2 in the SN of Parkinson's disease patients. Taken together, these results suggest that PARIS accumulation might distort the balance of glucose metabolism, providing clues for understanding mechanism underlying selective DNs death by PARIS. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. International Advisory Councils and Internationalization of Governance: A Qualitative Analysis

    Science.gov (United States)

    Mihut, Georgiana; Altbach, Philip G.; Salmi, Jamil

    2016-01-01

    This paper discusses the emergence of international advisory councils (IACs) at universities around the world and introduces the concept of internationalization of governance. Global trends in the field of higher education, such as the quest to create world-class universities and advance in global rankings, the rise of new public management, and…

  2. China's Strategy for the Internationalization of Higher Education: An Overview

    Science.gov (United States)

    Yang, Rui

    2014-01-01

    Over the past decades, the internationalization of higher education in China has had considerable achievements, and has contributed to the current transformation of the Chinese system into one of the largest and arguably most promising ones in the world. Setting the Chinese experience in an international context, this article assesses the latest…

  3. Center-periphery management in the internationalization of executive masters

    Directory of Open Access Journals (Sweden)

    Ana Christina Celano Teixeira

    2018-03-01

    Full Text Available This article analyzes the process of internationalization of the International Masters Program for Managers (IMPM started in 2012 from a partnership established with a Brazilian institution. Created in 1995 by Henry Mintzberg – also the current director – the IMPM adopted a heterodox model challenging the US traditional MBA model, Mintzberg’s moto “Managers, Not MBA” suggests a new focus on managers instead of overemphasizing analysis and technique. From a critical perspective, this study identifies that, although proposing an appreciation of the culture of the different places where the international modules are hosted, the IMPM still adopts the Anglo-Saxon logic of knowledge imposition. The study reflects the expectation that, when considering the internationalization of management educational programs, from a critical point of view, the voices of peripheral countries are heard, promoting a better balance between the production and consumption of knowledge on management in the contemporary global context. It is necessary, therefore, to work in order to create a more dialogical movement between center and periphery, establishing a dynamic that considers not only cultural aspects, but also that recognizes the production of knowledge in both contexts.

  4. Internationalization of Higher Education in China: Chinese-Foreign Cooperation in Running Schools and the Introduction of High-Quality Foreign Educational Resources

    Science.gov (United States)

    Tan, Zhen

    2009-01-01

    With the acceleration of the internationalization process of higher education in China, the Chinese-foreign cooperation in running schools (CFCRS) has been developing at an expeditious pace nowadays. It positively enhances the internationalization process of Chinese higher education and greatly contributes to providing the society with talents.…

  5. Recombinant factor VIIa treatment for asymptomatic factor VII deficient patients going through major surgery.

    Science.gov (United States)

    Livnat, Tami; Shenkman, Boris; Spectre, Galia; Tamarin, Ilia; Dardik, Rima; Israeli, Amnon; Rivkind, Avraham; Shabtai, Moshe; Marinowitz, Uri; Salomon, Ophira

    2012-07-01

    Factor VII deficiency is the most common among the rare autosomal recessive coagulation disorders worldwide. In factor VII deficient patients, the severity and clinical manifestations cannot be reliably determined by factor VII levels. Severe bleeding tends to occur in individuals with factor VII activity levels of 2% or less of normal. Patients with 2-10% factor VII vary between asymptomatic to severe life threatening haemorrhages behaviour. Recombinant factor VIIa (rFVIIa) is the most common replacement therapy for congenital factor VII deficiency. However, unlike haemophilia patients for whom treatment protocols are straight forward, in asymptomatic factor VII deficiency patients it is still debatable. In this study, we demonstrate that a single and very low dose of recombinant factor VIIa enabled asymptomatic patients with factor VII deficiency to go through major surgery safely. This suggestion was also supported by thrombin generation, as well as by thromboelastometry.

  6. Tissue Factor-Factor VII Complex As a Key Regulator of Ovarian Cancer Phenotypes.

    Science.gov (United States)

    Koizume, Shiro; Miyagi, Yohei

    2015-01-01

    Tissue factor (TF) is an integral membrane protein widely expressed in normal human cells. Blood coagulation factor VII (fVII) is a key enzyme in the extrinsic coagulation cascade that is predominantly secreted by hepatocytes and released into the bloodstream. The TF-fVII complex is aberrantly expressed on the surface of cancer cells, including ovarian cancer cells. This procoagulant complex can initiate intracellular signaling mechanisms, resulting in malignant phenotypes. Cancer tissues are chronically exposed to hypoxia. TF and fVII can be induced in response to hypoxia in ovarian cancer cells at the gene expression level, leading to the autonomous production of the TF-fVII complex. Here, we discuss the roles of the TF-fVII complex in the induction of malignant phenotypes in ovarian cancer cells. The hypoxic nature of ovarian cancer tissues and the roles of TF expression in endometriosis are discussed. Arguments will be extended to potential strategies to treat ovarian cancers based on our current knowledge of TF-fVII function.

  7. Plasma factor VII-activating protease is increased by oral contraceptives and induces factor VII activation in-vivo

    DEFF Research Database (Denmark)

    Sidelmann, Johannes J; Skouby, Sven O; Kluft, Cornelis

    2011-01-01

    Oral contraceptive (OC) use influences the hemostatic system significantly and is a risk factor for development of cardiovascular disease. Factor VII-activating protease (FSAP) has potential effects on hemostasis. The 1601GA genotype of the 1601G/A polymorphism in the FSAP gene expresses a FSAP...... progestins. FSAP genotypes, FSAP and factor VII (FVII) plasma measures were assessed at baseline and after 6 cycles of OC. The 1601GA genotype was present in 49 (8.3%) of the women and was associated with significantly reduced levels of FSAP (P=0.001). OC use increased FSAP antigen by 25% and FSAP activity...

  8. PINK1 Primes Parkin-Mediated Ubiquitination of PARIS in Dopaminergic Neuronal Survival

    Directory of Open Access Journals (Sweden)

    Yunjong Lee

    2017-01-01

    Full Text Available Mutations in PTEN-induced putative kinase 1 (PINK1 and parkin cause autosomal-recessive Parkinson’s disease through a common pathway involving mitochondrial quality control. Parkin inactivation leads to accumulation of the parkin interacting substrate (PARIS, ZNF746 that plays an important role in dopamine cell loss through repression of proliferator-activated receptor gamma coactivator-1-alpha (PGC-1α promoter activity. Here, we show that PARIS links PINK1 and parkin in a common pathway that regulates dopaminergic neuron survival. PINK1 interacts with and phosphorylates serines 322 and 613 of PARIS to control its ubiquitination and clearance by parkin. PINK1 phosphorylation of PARIS alleviates PARIS toxicity, as well as repression of PGC-1α promoter activity. Conditional knockdown of PINK1 in adult mouse brains leads to a progressive loss of dopaminergic neurons in the substantia nigra that is dependent on PARIS. Altogether, these results uncover a function of PINK1 to direct parkin-PARIS-regulated PGC-1α expression and dopaminergic neuronal survival.

  9. Do Banks Benefit from Internationalization? Revisiting the Market Power-Risk Nexus*

    NARCIS (Netherlands)

    Buch, Claudia M.; Koch, Catherine T.; Koetter, Michael

    We analyze the impact of bank internationalization on domestic market power (Lerner index) and risk for German banks. Risk is measured by the official declaration of regulatory authorities that a bank is distressed. We distinguish the volume of foreign assets, the number of foreign countries, and

  10. Value Creation from Internationalization of Sugar Cane by-products: a multi-stakeholder view of artisanal cachaça production

    Directory of Open Access Journals (Sweden)

    Daiane Mulling Neutzling

    2015-09-01

    Full Text Available Objective – The aim of this paper was to identify the strategies developed for internationalization in order to create value in the artisanal cachaça sector of Brazil. Design/methodology/approach – A multiple-case study was applied in two artisanal cachaçarias. we carried out in-depth, semi-structured interviews with different stakeholders involved in supporting internationalization of these companies. To select the stakeholders we used snowball sampling. The content of the interviews was categorized and analysed according to accepted theory. Findings – Our study provides an overview of the organization and structure of the cachaçarias and reveals how internationalization is adding value to this network from a multi-stakeholder view. The support of the multi-stakeholder network is in an early stage, but it offers a promising future, since there is a consumer market being developed. Political power is needed to regulate the industry. Practical implications – Business internationalization of the handmade cachaça sector is a challenge, as most companies are small and do not have adequate financial resources or proper knowledge regarding international markets. Regulatory stakeholders support the cachaçarias in standardizing production and developing international strategies. The results can help to better understand the importance of collaboration embedded in stakeholder network relationships. Originality/value – Empirical research on internationalization in developing countries, especially in small and mediums sized firms is still very limited. We have shown that companies can benefit from specific organization structures when developing relationships within multi-stakeholder networks.

  11. The internet as an alternative path to internationalization?

    OpenAIRE

    Sinkovics, Noemi; Sinkovics, Rudolf R.; Jean, Ruey Jer Bryan

    2013-01-01

    Purpose: While the internet enjoys increasing interest regarding its potential to extend the global reach of firms, especially small and medium-sized firms (SMEs), little work has been done on the viability of the internet as a new and effective path to internationalization. Specifically, it is unclear how the internet can successfully support export marketing. The purpose of this paper is to examine the drivers and performance outcomes of two patterns of internet use supporting export market...

  12. The Internationalization of Chinese Firms: Entry Mode Choice

    OpenAIRE

    Zhang, Xu

    2010-01-01

    Chinese firms and other emerging markets firms aim to select a favourable entry mode to start or expand their international business, thus this is significant issue for research. This study demonstrates that the Chinese firms’ choice of entry mode is determined by internal-factors, external-factors and transaction cost factors. This is illustrated through the investigation of a case study of the Haier Group’s choice of entry mode and internationalization. Therefore, four processes of choice o...

  13. Paris-Princeton Lectures on Mathematical Finance

    CERN Document Server

    Carmona, René A; Kohatsu-Higa, Arturo; Lasry, Jean-Michel; Lions, Pierre-Louis; Pham, Huyên; Taflin, Erik

    2007-01-01

    The Paris-Princeton Lectures in Financial Mathematics, of which this is the third volume, will, on an annual basis, publish cutting-edge research in self-contained, expository articles from outstanding - established or upcoming! - specialists. The aim is to produce a series of articles that can serve as an introductory reference for research in the field. It arises as a result of frequent exchanges between the finance and financial mathematics groups in Paris and Princeton. The present volume sets standards with articles by René Carmona, Ivar Ekeland/Erik Taflin, Arturo Kohatsu-Higa, Pierre-Louis Lions/Jean-Michel Lasry, and Hyuên Pham.

  14. Wartime Paris, cirrhosis mortality, and the ceteris paribus assumption.

    Science.gov (United States)

    Fillmore, Kaye Middleton; Roizen, Ron; Farrell, Michael; Kerr, William; Lemmens, Paul

    2002-07-01

    This article critiques the ceteris paribus assumption, which tacitly sustains the epidemiologic literature's inference that the sharp decline in cirrhosis mortality observed in Paris during the Second World War derived from a sharp constriction in wine consumption. Paris's wartime circumstances deviate substantially from the "all else being equal" assumption, and at least three other hypotheses for the cirrhosis decline may be contemplated. Historical and statistical review. Wartime Paris underwent tumultuous changes. Wine consumption did decline, but there were, as well, a myriad of other changes in diet and life experience, many involving new or heightened hardships, nutritional, experiential, institutional, health and mortality risks. Three competing hypotheses are presented: (1) A fraction of the candidates for cirrhosis mortality may have fallen to more sudden forms of death; (2) alcoholics, heavy drinkers and Paris's clochard subpopulation may have been differentially likely to become removed from the city's wartime population, whether by self-initiated departure, arrest and deportation, or death from other causes, even murder; and (3) there was mismeasurement in the cirrhosis mortality decline. The alcohol-cirrhosis connection provided the template for the alcohol research effort (now more than 20 years old) aimed at re-establishing scientific recognition of alcohol's direct alcohol-problems-generating associations and causal responsibilities. In a time given to reports of weaker associations of the alcohol-cirrhosis connection, the place and importance of the Paris curve in the wider literature, as regards that connection, remains. For this reason, the Paris findings should be subjected to as much research scrutiny as they undoubtedly deserve.

  15. Factor VII deficiency: a single-center experience.

    Science.gov (United States)

    Salcioglu, Zafer; Akcay, Arzu; Sen, Hulya Sayilan; Aydogan, Gonul; Akici, Ferhan; Tugcu, Deniz; Ayaz, Nuray Aktay; Baslar, Zafer

    2012-11-01

    Congenital factor VII deficiency is the most common form of rare coagulation factor deficiencies. This article presents a retrospective evaluation of 73 factor VII deficiency cases that had been followed at our center. The study consisted of 48 males and 25 females (2 months-19 years). Thirty-one (42.5%) of them were asymptomatic. Out of symptomatic patients, 17 had severe clinical symptoms, whereas 8 presented with moderate and 17 with mild symptoms. The symptoms listed in order of frequency were as follows: epistaxis, petechia or ecchymose, easy bruising, and oral cavity bleeding. The genotype was determined in 8 patients. Recombinant activated factor VII (rFVIIa) was used to treat 49 bleeding episodes in 8 patients after 2002. In 2 patients with repeated central nervous system bleeding prophylaxis with rFVIIa was administered. No allergic and thrombotic events were observed during both treatment and prophylaxis courses. Antibody occurrence was not detected in the patients during treatment.

  16. PARIS II: Computer Aided Solvent Design for Pollution Prevention

    Science.gov (United States)

    This product is a summary of U.S. EPA researchers' work developing the solvent substitution software tool PARIS II (Program for Assisting the Replacement of Industrial Solvents, version 2.0). PARIS II finds less toxic solvents or solvent mixtures to replace more toxic solvents co...

  17. Student Perceptions of Internationalization, Multiculturalism, and Diversity in the Business School

    Science.gov (United States)

    Mitchell, Matthew C.; Vandegrift, Darcie

    2014-01-01

    Over the last five decades, business schools all over the world have adapted their strategies for introducing the theoretical and pedagogical consequences of globalization. Educational institutions have gone to great lengths to internationalize their curricula to stay current with the most recent trends in the globalizing economy. As this…

  18. Studies on normal-conducting coils for Wendelstein VII-X

    International Nuclear Information System (INIS)

    Harmeyer, E.; Kisslinger, J.; Rau, F.; Sapper, J.; Wobig, H.

    1990-08-01

    For Wendelstein VII-X, the next step stellarator experiment at IPP Garching, a Helias configuration has been chosen. The goals of Wendelstein VII-X are to continue the development of the modular stellarator and to demonstrate the reactor capability of this stellarator line. The main data of the selected HS5-10 configuration with five field periods are: major radius R 0 = 5.5 m, magnetic induction B 0 = 3 T and stored magnetic energy W ≅ 0.6 GJ. For comparison with the superconducting coil system which is foreseen for Wendelstein VII-X, a pulsed water-cooled normal-conducting version has been designed in order to explore the limitations and restrictions of this approach. Limitations are the high ohmic power dissipated in the coils and the electric energy currently available at IPP. Normal-conducting coils would allow to apply the well-known techniques in manufactoring these coils, as successful in use in the Wendelstein VII-AS experiment. But these techniques are applicable also for the conductor proposed for the superconducting coils of Wendelstein VII-X. In this report the time-dependent current and resistance of the coil system circuit is considered; the electric power needed, the total dissipated energy, and the temperature rise of the coil copper is calculated. Scaling laws are derived and parameter studies are made by varying the geometrical dimensions of the system. (orig.)

  19. Pariisi kord = Paris' move / João Francisco Figueira

    Index Scriptorium Estoniae

    Figueira, João Francisco, 1968-

    2009-01-01

    Pariisi nõustamisprojektide rahvusvahelisest võistlusest "Le Grand Pari(s)". Sooviti saada julget ja elluviidavat projekti Pariisi arenguks aastani 2050. Osales kümme kutsutud arhitektide, planeerijate ja ekspertide töörühma. Osade tööde mõningaid aspekte tutvustav käsitlus

  20. Neutral transport calculations for W VII-X. First applications to W VII-X

    International Nuclear Information System (INIS)

    Sardei, F.

    1988-01-01

    Results of neutral gas transport calculations obtained with the DEGAS code are presented for a W VII-AS model plasma and a source of neutrals due to limiter recycling. For typical profiles of the plasma parameters as predicted for an ECRH discharge, the simulation yields a radial drop of the average neutral population by a factor of 30. The neutrals are strongly localized near the limiter and have a poloidal minimum at its opposite side. For a W VII-X configuration (HS4-12), a neutral source given by a high recycling ion flux equally distributed over the wall is considered. For an ion density of 5 x 10 1 3 /cc and 30 eV edge temperature, the neutrals originating from the wall completely ionize within the ergodic region. The corresponding average energy of cx neutrals hitting the wall is less than 30 eV. Neutral penetration into the plasma locally depends on the distance between wall and separatrix

  1. Tissue Factor–Factor VII Complex as a Key Regulator of Ovarian Cancer Phenotypes

    Directory of Open Access Journals (Sweden)

    Shiro Koizume

    2015-01-01

    Full Text Available Tissue factor (TF is an integral membrane protein widely expressed in normal human cells. Blood coagulation factor VII (fVII is a key enzyme in the extrinsic coagulation cascade that is predominantly secreted by hepatocytes and released into the bloodstream. The TF–fVII complex is aberrantly expressed on the surface of cancer cells, including ovarian cancer cells. This procoagulant complex can initiate intracellular signaling mechanisms, resulting in malignant phenotypes. Cancer tissues are chronically exposed to hypoxia. TF and fVII can be induced in response to hypoxia in ovarian cancer cells at the gene expression level, leading to the autonomous production of the TF–fVII complex. Here, we discuss the roles of the TF–fVII complex in the induction of malignant phenotypes in ovarian cancer cells. The hypoxic nature of ovarian cancer tissues and the roles of TF expression in endometriosis are discussed. Arguments will be extended to potential strategies to treat ovarian cancers based on our current knowledge of TF–fVII function.

  2. Reaction of Pu(VII) with certain aliphatic alcohols in basic media

    International Nuclear Information System (INIS)

    Tananaev, I.G.

    1992-01-01

    The kinetics of Pu(VII) reduction by methanol and ethanol in 0.5-5.0 M NaOH are studied by spectrophotometry. The rate constants of the studied reactions are calculated. The rate constants increase in concert with the reductant concentration but sharply decrease with increasing base concentration in the reaction medium. The principal factor affecting the rate of Pu(VII) reduction by alcohols is probably steric in nature. Secondary alcohols are more active in basic medium. The resulting experimental data also confirm the very strong oxidizing capability of Pu(VII), the rate of reduction of which by CH 3 OH or C 2 H 5 OH compared with Np(VII) under similar conditions is 20-50 times faster

  3. Internationalization and technological leapfrogging in the pharmaceutical industry

    OpenAIRE

    Suma Athreye; Andrew Godley

    2009-01-01

    The pre-refereed author version of this article was published as a UNI-MERIT Working Paper under the title “Internationalising to create Firm Specific Advantages: Leapfrogging strategies of U.S. Pharmaceutical firms in the 1930s and 1940s & Indian Pharmaceutical firms in the 1990s and 2000s”. The paper can be downloaded from the UNU-MERIT website from the following link: http://arno.unimaas.nl/show.cgi?fid=12607. Internationalization is a useful strategy for gaining firm-specific technolog...

  4. Internationalization strategy of Altis Hotels to Madrid, Spain

    OpenAIRE

    Nunes, Joana Raquel Augusto

    2013-01-01

    A Work Project, presented as part of the requirements for the Award of a Masters Degree in Management from the NOVA – School of Business and Economics Altis Hotels Group is a successful family owned hotel group that holds a portfolio of several hotels in Lisbon, Portugal. Despite the success in the Portuguese market, aspects 3 such as the current economic crisis led Altis to consider the option of internationalizing and exploring opportunities in new markets. Initially, the company’s co...

  5. Fight or buy? A comparison of internationalization strategies.

    OpenAIRE

    Roland Kirstein

    2013-01-01

    The paper evaluates three internationalization strategies of a company that considers invading a foreign market: • It can buy a firm that resides in the target market (acquisition strategy), • it can produce at home and export into the target market (export strategy), • or the two firms can agree upon produce in the invader's home country and sell the products in the target market (OEM strategy). For simplicity, we assume that the incumbent firm in the target country has a monopoly position. ...

  6. Post Paris and November 8, 2016

    Science.gov (United States)

    Busalacchi, A. J.

    2016-12-01

    COP 21 in Paris, as historic as it was, established the necessary, but not the sufficient. The signatories to the landmark Paris accord are a coalition of the willing, but their pledges are only as good as the sustained will of individual countries to adhere to their commitments. The U.S. presidential election has demonstrated how easily uncertainty can be added. Even if all countries abide by the Paris climate agreement, capping global mean temperatures to 2oC will likely require net zero greenhouse gas emissions by 2085 and substantial negative emissions over the long term. Before the Paris agreement was finished, it was clear that the pledged emission cuts by 2030 would not be sufficient in and of themselves, to stay under 2oC. Given the accumulation of greenhouse gases to date, limiting warming to a maximum of 2oC would require bending the curve of global emissions by 2020, i.e., over the next four years. If the past is a prologue, without even taking into account an emergence from the global recession, we stand a realistic chance of blowing right past the 2oC target. What, then, are the challenges going forward? Is 2oC a real goal that is attainable, or is it a stretch goal? Meeting a 2oC target is a function of when mitigation begins in earnest, the rate of mitigation, and the rate and amount of carbon sequestration. What are the implications of this trade space? While much effort has been put into designing a climate observing system from a science perspective, relatively little thought has been put into determining what observations are needed to support policy decisions, mitigation, and verify the Intended Nationally Determined Contributions that resulted from the Paris Agreement. If 2oC is a stretch goal, intellectual honesty requires that we consider mitigation and adaptation in tandem, and not as either/or. Similarly, even with all its attendant ethical dilemmas, it is important to thoroughly study geoengineering so that policy makers have a robust

  7. Structural incorporation of MgCl2 into ice VII at room temperature

    Science.gov (United States)

    Watanabe, Mao; Komatsu, Kazuki; Noritake, Fumiya; Kagi, Hiroyuki

    2017-05-01

    Raman spectra and X-ray diffraction patterns were obtained from 1:100 and 1:200 \\text{MgCl}2:\\text{H}2\\text{O} solutions (in molar ratio) at pressures up to 6 GPa using diamond anvil cells (DACs) and compared with those of pure water. The O-H stretching band from ice VII crystallized from the 1:200 solution was approximately 10 cm-1 higher than that of pure ice VII. The phase boundaries between ice VII and VIII crystallized from the MgCl2 solutions at 4 GPa were 2 K lower than those of pure ice VII and VIII. These observations indicate that ice VII incorporates MgCl2 into its structure. The unit cell volumes of ice VII crystallized from pure water and the two solutions coincided with each other within the experimental error, and salt incorporation was not detectable from the cell volume. Possible configurations of ion substitution and excess volume of ice VIII were simulated on the basis of density functional theory (DFT) calculations.

  8. Comprehensive Internationalization: Examining the What, Why, and How at Community Colleges

    Science.gov (United States)

    Butler, Debra-Ann C.

    2016-01-01

    Community colleges enroll nearly half of the total U.S. undergraduates, have the most diverse student population, and serve as the only contact with postsecondary education for many students. Community colleges have engaged in internationalization efforts for decades. Most rely on study abroad and international students as the only methods to…

  9. Measuring the gradualist approach to internationalization: Empirical evidence from the wine sector.

    Science.gov (United States)

    Clavel San Emeterio, Mónica; Fernández-Ortiz, Rubén; Arteaga-Ortiz, Jesús; Dorta-González, Pablo

    2018-01-01

    The objective of this paper is to fill a gap in the literature on internationalization, in relation to the absence of objective and measurable performance indicators for the process of how firms sequentially enter external markets. To that end, this research develops a quantitative tool for use as a performance indicator of gradualness for firms entering external markets at a sectoral level. The performance indicator is based on firms' export volumes, number of years operating in the export market, geographic areas targeted for export and when exports began to each area. The indicator is tested empirically in the wine sector. The main contribution of this study is the creation of a reliable international priority index, which can serve more widely as a valuable tool because of its potential use in other industry sectors and geographic areas, and which would allow the analysis of how geographically differentiated internationalization strategies develop.

  10. New perspectives on internationalization and competitiveness integrating economics, innovation and higher education

    CERN Document Server

    2015-01-01

    This volume showcases contributions from leading academics, educators and policymakers derived from two workshops hosted by the Interdisciplinary Center for Economic Science (ICES) at George Mason University on internationalization and competitiveness. It aims to present key areas of current research and to identify basic problems within the field to promote further discussion and research. This book is organized into two sections, focusing on: science and economics and innovation policy and its measurement, with an underlying emphasis on exploring connections across disciplines and across research, practice and policy. The first workshop was held at George Mason University (GMU) in Arlington, VA, USA in March 2013 and a second, building on the key results from the first, was held at the Royal Institute of Technology (KTH) in Stockholm, Sweden in October 2013. A variety of problems were discussed and several interdisciplinary concepts in internationalization and competitiveness have already emerged from the...

  11. Revisiting the Internationalization of Services

    DEFF Research Database (Denmark)

    Ørberg Jensen, Peter D.; Hazarbassanova, Denitsa; Merchant, Hemant

    2014-01-01

    The growing importance of services in the global economy and international business practice has attracted the attention of international business scholars, policy-makers, as well as the business community. Yet previous research has shown that research-based knowledge of the field is limited...... and does not reflect the global economic importance of services. Building on previous research on the internationalization of service firms and activities, we review the development from 2008 until 2013. We review articles published in five leading international business journals, including a total of 1...... in the context of the international business environment. We extend recommendations for future research to address the robustness of existing definitions and classifications of industries, and to involve more the new institutionalism perspective. We conclude that there are many underexplored questions, yet...

  12. Reviewing the relationship between technological innovation and internationalization from a dynamic capabilities’ perspective

    NARCIS (Netherlands)

    Kets, Jaan

    2015-01-01

    Considerable attention has been paid to the reciprocal relationship between technological innovation and internationalization. However, despite research efforts in identifying if and how these two strategic processes influence each other, the literature is inundated with inconsistencies,

  13. Geç Ortaçağ Avrupası’nın Meşhur ve Gizemli Şehri Paris (Paris That Was Famous and Mysterious City of the Late Medieval Europe

    Directory of Open Access Journals (Sweden)

    Abdulhalik BAKIR

    2010-10-01

    Full Text Available Paris is one of the most important capitals of the middle age. Actually, this city is universecity. Namely, Paris was remembered as a univercity, education center and art and architecture center. Paris appeared differently from the other cities. Here was an important city that East culture and West culture mixed with each other. In its environment, there were cities that have a traditional structure. It carries all the facilities of the city structure in the later middle ages. Namely, Paris is remembered firstly, while city structure is described. Like Chretien de Troyes described, Paris had the culture that made France as the first heritage of Roma and Greek. Paris is a colourful city. Perhaps, France had the most crowd population because of these facilities of Paris. Generally, undoubtedly, these facilities had a big role about the development of France civilization in the 13th century. So, in this study, we will study to introduce Paris with social-economic and culturel angles and give its appearance in the later middle ages.

  14. DINAMIC ASPECTS OF INTERNATIONALIZATION IN MODERN MEDIA WORD CREATION

    Directory of Open Access Journals (Sweden)

    Ratsiburskaya Larisa Viktorovna

    2014-12-01

    Full Text Available In the context of globalization at the turn of XX–XXI centuries there are various manifestations of internationalization in the Russian language notified by linguists. Internationalization in modern Russian word-formation reveals itself in derivational activity of loan morphemes and models, as well as in the borrowing of new derivational morphemes. In modern mass media word creation well-known derivational affixes (the prefixes anti-, contr-, pseudo-, quasi-, super-, hyper-, ultra-, ex-, as well as some new derivational elements (the prefix mega-, the suffix -ing, -land, -wood, suffixed -gate are noted, and the author puts forward arguments to substantiate their morphemic status. "Ameroglobalization", and in particular the influence of the English language on the semantics of prefixes, contributes to the growth of word-building activity and productivity of the prefixes which are of Greek-Latin origin. The appearance of new word-building affixes in the modern Russian language is affected by active usage of the corresponding foreign morphemes in the journalists' word creation, in media texts and on the internet forums. Activization of foreign derivation elements in the media word creation is conditioned by sociocultural factors. Advertisement and mass media encourage the trend of using angloamericanisms and facilitate growth of word-building productivity of new affixes and new word-building models.

  15. Report of Committee for JAEA Internationalization Initiative (Translated document)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-07-15

    In global circumstances surrounding nuclear energy, the role expected by the Japan Atomic Energy Agency (JAEA) is becoming increasingly important. JAEA has promoted an initiative for an international hub in order to increase the scientific competitiveness of Japan and make international contributions, by gathering excellent researchers from the entire world with the latest facilities. Also, JAEA has established the 'Committee for JAEA Internationalization Initiative', which will discuss issues such as environmental improvement for accepted foreigners, direction of efforts for internationalization initiative and strategies to improve the current situation. This report mentions the results of the committee's discussion including current issues for the initiative and recommendations for their solution, as well as issues to be discussed in order to enhance international awareness of JAEA staff. The following is the summary of the recommendations for the initiative: Set up local teams that focus on the situation of each site in order to provide detailed support for foreigners from diversified backgrounds. Develop systems for emergency situations to provide information for safety swiftly for foreigners and confirm their safety, in addition to preparing emergency goods. Prepare bilingual documents and systems that foreigners need to use for their work based on importance and frequency of use of such systems and documents. (author)

  16. Report of Committee for JAEA Internationalization Initiative (Translated document)

    International Nuclear Information System (INIS)

    2013-07-01

    In global circumstances surrounding nuclear energy, the role expected by the Japan Atomic Energy Agency (JAEA) is becoming increasingly important. JAEA has promoted an initiative for an international hub in order to increase the scientific competitiveness of Japan and make international contributions, by gathering excellent researchers from the entire world with the latest facilities. Also, JAEA has established the 'Committee for JAEA Internationalization Initiative', which will discuss issues such as environmental improvement for accepted foreigners, direction of efforts for internationalization initiative and strategies to improve the current situation. This report mentions the results of the committee's discussion including current issues for the initiative and recommendations for their solution, as well as issues to be discussed in order to enhance international awareness of JAEA staff. The following is the summary of the recommendations for the initiative: Set up local teams that focus on the situation of each site in order to provide detailed support for foreigners from diversified backgrounds. Develop systems for emergency situations to provide information for safety swiftly for foreigners and confirm their safety, in addition to preparing emergency goods. Prepare bilingual documents and systems that foreigners need to use for their work based on importance and frequency of use of such systems and documents. (author)

  17. Age-dependent regulation of ERF-VII transcription factor activity in Arabidopsis thaliana.

    Science.gov (United States)

    Giuntoli, Beatrice; Shukla, Vinay; Maggiorelli, Federica; Giorgi, Federico M; Lombardi, Lara; Perata, Pierdomenico; Licausi, Francesco

    2017-10-01

    The Group VII Ethylene Responsive Factors (ERFs-VII) RAP2.2 and RAP2.12 have been mainly characterized with regard to their contribution as activators of fermentation in plants. However, transcriptional changes measured in conditions that stabilize these transcription factors exceed the mere activation of this biochemical pathway, implying additional roles performed by the ERF-VIIs in other processes. We evaluated gene expression in transgenic Arabidopsis lines expressing a stabilized form of RAP2.12, or hampered in ERF-VII activity, and identified genes affected by this transcriptional regulator and its homologs, including some involved in oxidative stress response, which are not universally induced under anaerobic conditions. The contribution of the ERF-VIIs in regulating this set of genes in response to chemically induced or submergence-stimulated mitochondria malfunctioning was found to depend on the plant developmental stage. A similar age-dependent mechanism also restrained ERF-VII activity upon the core-hypoxic genes, independently of the N-end rule pathway, which is accounted for the control of the anaerobic response. To conclude, this study shed new light on a dual role of ERF-VII proteins under submergence: as positive regulators of the hypoxic response and as repressors of oxidative-stress related genes, depending on the developmental stage at which plants are challenged by stress conditions. © 2017 John Wiley & Sons Ltd.

  18. [Selective internationalization: foreign workers and Japanese society].

    Science.gov (United States)

    Ito, R

    1990-01-01

    Japan's December 1989 revision of the law on immigration and recognition of refugees was intended to provide greater felxibility for employment of foreigners with specialized skills or professional qualifications while excluding migrant workers. This policy, referred to as selective internationalization by the author, represents an effort by the government to early 1980s and to changes in the Japanese economy which after decades of rapid growth is entering a new phase of diversification. The ideal of national homogeneity has prevented formulation of any coherent policy of integrating Japan's foreign born population, mostly descendents of laborers from Japan's former colonies. In 1988, Japan's 677,000 Korean residents constituted 72% of the foreign population registered in Japan. As of 1988, some 40,000 foreigners were registered as residents and permitted to work in any of several well-defined areas. The number, while small, is growing. Illegal migrants are defined essentially as foreigners exercising economic activities not authorized by their visas. The number of such workers is notoriously difficult to estimate, but the number of expulsions for labor violations increased by 4700 in 1989 to 22,600, suggesting that the problem is growing. The Ministry of Justice estimated the number of foreigners in irregular situations at 70,000 in 1988, and it has probably reached 120,000 at present. The number of foreign workers, authorized or not, is estimated at 150-160,000 or .3% of the active population. The 1989 revision of the immigration law does not constitute a foreign labor policy, but it does clearly signal the end of complete protectionism vis a vis the labor market which characterized Japan's period of rapid growth. Internationalization of the labor market reflects 2 concerns, provision of highly qualified employees to enable large enterprises to adapt more readily to changing international conditions, and continued control over the foreign labor supply of small

  19. SUMOylation of the KRAB zinc-finger transcription factor PARIS/ZNF746 regulates its transcriptional activity

    International Nuclear Information System (INIS)

    Nishida, Tamotsu; Yamada, Yoshiji

    2016-01-01

    Parkin-interacting substrate (PARIS), a member of the family of Krüppel-associated box (KRAB)-containing zinc-finger transcription factors, is a substrate of the ubiquitin E3 ligase parkin. PARIS represses the expression of peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α), although the underlying mechanisms remain largely unknown. In the present study, we demonstrate that PARIS can be SUMOylated, and its SUMOylation plays a role in the repression of PGC-1a promoter activity. Protein inhibitor of activated STAT y (PIASy) was identified as an interacting protein of PARIS and shown to enhance its SUMOylation. PIASy repressed PGC-1a promoter activity, and this effect was attenuated by PARIS in a manner dependent on its SUMOylation status. Co-expression of SUMO-1 with PIASy completely repressed PGC-1a promoter activity independently of PARIS expression. PARIS-mediated PGC-1a promoter repression depended on the activity of histone deacetylases (HDAC), whereas PIASy repressed the PGC-1a promoter in an HDAC-independent manner. Taken together, these results suggest that PARIS and PIASy modulate PGC-1a gene transcription through distinct molecular mechanisms. -- Highlights: •PARIS can be SUMOylated in vivo and in vitro. •SUMOylation of PARIS functions in the repression of PGC-1a promoter activity. •PIASy interacts with PARIS and enhances its SUMOylation. •PIASy influences PARIS-mediated repression of PGC-1a promoter activity.

  20. SUMOylation of the KRAB zinc-finger transcription factor PARIS/ZNF746 regulates its transcriptional activity

    Energy Technology Data Exchange (ETDEWEB)

    Nishida, Tamotsu, E-mail: nishida@gene.mie-u.ac.jp; Yamada, Yoshiji

    2016-05-13

    Parkin-interacting substrate (PARIS), a member of the family of Krüppel-associated box (KRAB)-containing zinc-finger transcription factors, is a substrate of the ubiquitin E3 ligase parkin. PARIS represses the expression of peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α), although the underlying mechanisms remain largely unknown. In the present study, we demonstrate that PARIS can be SUMOylated, and its SUMOylation plays a role in the repression of PGC-1a promoter activity. Protein inhibitor of activated STAT y (PIASy) was identified as an interacting protein of PARIS and shown to enhance its SUMOylation. PIASy repressed PGC-1a promoter activity, and this effect was attenuated by PARIS in a manner dependent on its SUMOylation status. Co-expression of SUMO-1 with PIASy completely repressed PGC-1a promoter activity independently of PARIS expression. PARIS-mediated PGC-1a promoter repression depended on the activity of histone deacetylases (HDAC), whereas PIASy repressed the PGC-1a promoter in an HDAC-independent manner. Taken together, these results suggest that PARIS and PIASy modulate PGC-1a gene transcription through distinct molecular mechanisms. -- Highlights: •PARIS can be SUMOylated in vivo and in vitro. •SUMOylation of PARIS functions in the repression of PGC-1a promoter activity. •PIASy interacts with PARIS and enhances its SUMOylation. •PIASy influences PARIS-mediated repression of PGC-1a promoter activity.

  1. Core Processes Roadmap to Deploy the Higher Education Institution's Internationalization Strategy

    Directory of Open Access Journals (Sweden)

    Elena FLEACĂ

    2017-02-01

    Full Text Available Technological development, competition and globalisation are radically changing the landscape of higher education which maintains its crucial role in individual and societal advancement. Many higher education institutions are competing on increasing their attractiveness by providing innovative curricula, excellence in teaching and research opportunities. The paper attempts to tackle the push for stronger international presence which brings favourable conditions for internationalisation strategy at institutional level. Based on useful methods from quality management and business process reengineering, the author proposed a coherent organizational model for a higher education institution strategy, mainstreaming key areas as international mobility for students and staff, internationalization and improvement of curricula and new e-learning methods, and strategic cooperation, partnerships and capacity building with international stakeholders. The findings stress the benefits of a holistic approach in assuring the governance of internationalization strategy composed of three core processes groups - academic, research, and wider business relationships – so as to provide that process architecture is able to deliver a value added internationalised higher education offer.

  2. Paris-Princeton Lectures on Mathematical Finance

    CERN Document Server

    Çinlar, Erhan; Ekeland, Ivar; Jouini, Elyes; Scheinkman, José; Touzi, Nizar

    2004-01-01

    The Paris-Princeton Lectures in Financial Mathematics, of which this is the second volume, will, on an annual basis, publish cutting-edge research in self-contained, expository articles from outstanding - established or upcoming! - specialists. The aim is to produce a series of articles that can serve as an introductory reference for research in the field. It arises as a result of frequent exchanges between the finance and financial mathematics groups in Paris and Princeton. This volume presents the following articles: "Hedging of Defaultable Claims" by T. Bielecki, M. Jeanblanc, and M. Rutkowski; "On the Geometry of Interest Rate Models" by T. Björk; "Heterogeneous Beliefs, Speculation and Trading in Financial Markets" by J.A. Scheinkman, and W. Xiong.

  3. Internationalization of Higher Education: A Literature Review on Competency Approach

    OpenAIRE

    Chong Pui Yee

    2014-01-01

    This paper is a literature review on the internationalization of higher education focusing on staff competency in managing international students. This writing uncovered some empirical studies by researchers in a Malaysian context on the issue, challenges and expectation from both international students and university academics and administrators. International students faced great challenges in adjusting their life in Malaysia, these include different teaching and learning style, culture, la...

  4. Integration of Intercultural Competence in the Processes of Enterprise Internationalization: Possibilities of the Adaptation of the Model in the Operation of Small and Medium Enterprises

    Directory of Open Access Journals (Sweden)

    Jolita Vveinhardt

    2015-05-01

    Full Text Available The article briefly presents the problems identified during the studies carried out by the authors previously, i.e. the problems of intercultural competence and its integration in the processes of internationalization are disclosed. On the basis of the researches carried out the model of integration of intercultural competence in the internationalization processes is adapted, preparing the plan of development of intercultural competence in enterprises. At the end of the article the guidelines for the application of the model for development of internationalization of small and medium enterprises is presented.

  5. The German ''Energiewende''. Evaluation after the Paris-agreement; Die Deutsche Energiewende. Bewertung nach dem Klima-Abkommen von Paris

    Energy Technology Data Exchange (ETDEWEB)

    Roth, Eike

    2016-08-01

    The World-Climate-Summit 2016 in Paris agreed to exacerbated goals for climate protection. This paper will scrutinize whether Germany can comply with its Paris-obligations by continuing the ongoing German ''Energiewende''. The result is clear-cut: The German ''Energiewende'' is inadequate. Due to the cap-and-trade system of the EU the '''Energiewende''.

  6. Plasmodium falciparum ookinete expression of plasmepsin VII and plasmepsin X.

    Science.gov (United States)

    Li, Fengwu; Bounkeua, Viengngeun; Pettersen, Kenneth; Vinetz, Joseph M

    2016-02-24

    Plasmodium invasion of the mosquito midgut is a population bottleneck in the parasite lifecycle. Interference with molecular mechanisms by which the ookinete invades the mosquito midgut is one potential approach to developing malaria transmission-blocking strategies. Plasmodium aspartic proteases are one such class of potential targets: plasmepsin IV (known to be present in the asexual stage food vacuole) was previously shown to be involved in Plasmodium gallinaceum infection of the mosquito midgut, and plasmepsins VII and plasmepsin X (not known to be present in the asexual stage food vacuole) are upregulated in Plasmodium falciparum mosquito stages. These (and other) parasite-derived enzymes that play essential roles during ookinete midgut invasion are prime candidates for transmission-blocking vaccines. Reverse transcriptase PCR (RT-PCR) was used to determine timing of P. falciparum plasmepsin VII (PfPM VII) and plasmepsin X (PfPM X) mRNA transcripts in parasite mosquito midgut stages. Protein expression was confirmed by western immunoblot and immunofluorescence assays (IFA) using anti-peptide monoclonal antibodies (mAbs) against immunogenic regions of PfPM VII and PfPM X. These antibodies were also used in standard membrane feeding assays (SMFA) to determine whether inhibition of these proteases would affect parasite transmission to mosquitoes. The Mann-Whitney U test was used to analyse mosquito transmission assay results. RT-PCR, western immunoblot and immunofluorescence assay confirmed expression of PfPM VII and PfPM X in mosquito stages. Whereas PfPM VII was expressed in zygotes and ookinetes, PfPM X was expressed in gametes, zygotes, and ookinetes. Antibodies against PfPM VII and PfPM X decreased P. falciparum invasion of the mosquito midgut when used at high concentrations, indicating that these proteases play a role in Plasmodium mosquito midgut invasion. Failure to generate genetic knockouts of these genes limited determination of the precise role of

  7. FAKTOR-FAKTOR YANG MEMENGARUHI PRODUKSI GULA PTPN VII (PERSERO

    Directory of Open Access Journals (Sweden)

    Rizky Savitri

    2014-09-01

    Full Text Available ABSTRACTThis study aimed to analyze the influence of the level of sugar cane yield, labor, production process period, and supporting materials on the production of PTPN VII (Persero PG. Cinta Manis, as well as analyzing the elasticity of production and business scale  of PTPN VII (Persero PG. Cinta Manis. The method used to analyze the data were quantitative analysis of Cobb Douglas production function with ordinary least square method to observe variable influences of PG. Cinta Manis sugar production. Cobb Douglas estimation results indicate that the level of sugar cane yield, labor, production process period, and supporting materials affect sugar production in PTPN VII (Persero PG. Cinta Manis. Production elasticity of each production factor shows that the use of production factors is not yet optimal, while the production scale of the company is Increasing Return to Scale (IRTS in which the proportion of additional input will produce output with the larger proportion. Accordingly, company should utilize the factors of production optimally, improve the quality of human resources with various activities to improve skills, increase the productivity of land by having land intensification, and optimize milling period by improving the quality of machine.Keywords: PG. Cinta Manis, increasing return to scale, Cobb Douglas function, PTPN VIIABSTRAKPenelitian ini bertujuan menganalisis pengaruh tingkat rendemen, tenaga kerja, bahan pembantu dan lama lama giling terhadap produksi gula PTPN VII (Persero PG. Cinta Manis, sekaligus menganalisis elastisitas produksi dan skala usaha PTPN VII (Persero PG. Cinta Manis. Metode analisis data yang digunakan adalah  analisis kuantitatif. Analisis kuantitatif pada penelitian ini menggunakan fungsi produksi cobb douglas dengan metode ordinary least square untuk melihat pengaruh variabel-variabel yang telah ditentukan terhadap produksi gula PG. Cinta Manis. Hasil estimasi cobb douglas menunjukkan  bahwa tingkat

  8. Production and properties of monoclonal antibodies to human blood coagulation factor VII and factor VIIa

    International Nuclear Information System (INIS)

    Mann, P.; Nesbitt, J.A.; Ge, M.; Kisiel, W.

    1986-01-01

    Human factor VII is a trace vitamin K-dependent protein that circulates in blood as a single-chain precursor to a serine protease. Upon activation, two-chain factor VIIa activates factor x in the presence of tissue factor and calcium. Purified preparations of single-chain (SC) human factor VII and two-chain (TC) factor VIIa were utilized to immunize Balb/c mice. Spleen cells from these immunized mice were fused to a non-secreting NS-1 derivative of X63-Ag8 myeloma cells and grown in selective medium. Analysis of culture supernatants by EIA revealed several hybridomas that were secreting IgG specific for Sc-factor VII and TC-factor VIIa. In addition, several hybridomas secreted IgG that reacted equally well with factor VII and factor VIIa. One of the latter McAb (A-29) reacted with the heavy chain of factor VIIa and the intact factor VII molecule equally as judged by Western blotting. A-29 was produced in ascites fluid, purified and coupled to activated CH-Sepharose. Application of one liter of normal human plasma to 10 ml of this immunoadsorbent column, elution of factor VII and subsequent Western blot using 125 I-rabbit anti-human factor VII indicated a single species of factor VII(M/sub r/ = 50 KDa) in normal plasma. These specific factor VII/VIIa McAbs may prove useful in the analysis of these factors, and in the separation of SC-factor VII from TC-factor VIIa

  9. Perturbation fields in W VII-AS and Helias configurations

    International Nuclear Information System (INIS)

    Harmeyer, E.; Kisslinger, J.; Montvai, A.; Rau, F.; Wobig, H.

    1988-01-01

    Effects of pertubed topologies of the W VII-AS vacuum fields on the configuration with rational and irrational rotational transform are illustrated. Even small perturbation fields are unacceptable at rational values of the rotational transform. For example at a rotational transform = 1/2 in W VII-AS, when exceeding an effective homogeneous Bx/B = 3 x 10 -4 , the size of the rotational transform = 1/2 = 5/10 islands is doubled. At irrational values a Bx/B = 1/2% shows tolerable effects, for both W VII-AS and HS4-12. At rational values of the rotational transform = 1 near the edge, Bx/B values = 1/4 to 1/8% show a rather large increase of the aspect ratio, so an edge value of rotational transform = 1 should be avoided

  10. Internationalization, Deregulation and the Extension of Higher Education in Korea: A Further Note

    Science.gov (United States)

    Jin, Jang C.

    2015-01-01

    The Korean government implemented several educational policies to enhance internationalization of higher education such as deregulation of higher education, classroom instructions in English, and faculty publications in international refereed journals. However, the speed of globalization has been lagging behind (Green, 2015). Alternatively, this…

  11. Paris-Princeton lectures on mathematical finance 2002

    CERN Document Server

    2003-01-01

    The Paris-Princeton Lectures in Financial Mathematics, of which this is the first volume, will, on an annual basis, publish cutting-edge research in self-contained, expository articles from outstanding - established or upcoming! - specialists. The aim is to produce a series of articles that can serve as an introductory reference for research in the field. It arises as a result of frequent exchanges between the finance and financial mathematics groups in Paris and Princeton. The present volume sets standards with articles by P. Bank/H. Föllmer, F. Baudoin, L.C.G. Rogers, and M. Soner/N. Touzi.

  12. Bookmaker and pari-mutuel betting

    DEFF Research Database (Denmark)

    Koch, Alexander; Shing, Hui-Fai

    2008-01-01

    A widely documented empirical regularity in gambling markets is that bets on high probability events (a race won by a "favourite") have higher expected returns than bets on low probability events (a "longshot" wins). Such favourite-longshot (FL) biases however appear to be more severe and persist......A widely documented empirical regularity in gambling markets is that bets on high probability events (a race won by a "favourite") have higher expected returns than bets on low probability events (a "longshot" wins). Such favourite-longshot (FL) biases however appear to be more severe...... and persistent in bookmaker markets than in pari-mutuel markets; the latter sometimes exhibit no bias or a reverse FL bias. Our results help understand these differences: the odds grid in bookmaker markets leads to a built-in FL bias, whereas that used in pari-mutuel betting pushes these markets toward a reverse...

  13. MORTUARY MERGERS AND THE INTERNATIONALIZATION OF INTERMENT

    Directory of Open Access Journals (Sweden)

    David O. Whitten

    2001-01-01

    Full Text Available “Mortuary Mergers and the Internationalization of Interment” is a study ofthe death services industry’s response to a changing market. Throughout the industry and across national borders, independent mortuaries and cemeteries are merging or consolidating. International death services firms are structured much as the automobile, oil, and communications multinationals are. Monopolistic competition is increasingly replaced by national and international oligopoly that may well translate into monopoly in isolated markets and lead to antitrust action and regulation. The study develops the historical roots of the death services industry but concentrates on the revolution underway. The prospects for the industry in the twenty-first century conclude the paper.

  14. Reputation of multinational companies: Corporate social responsibility and internationalization

    Directory of Open Access Journals (Sweden)

    Javier Aguilera-Caracuel

    2017-10-01

    Full Text Available Purpose - The purpose of this paper is to use stakeholder theory as the theoretical reference framework to study the influence of internationalization (geographic international diversification and social performance on multinational companies’ (MNCs reputation. Design/methodology/approach - The authors confirm the research hypotheses using a sample of 113 US MNCs in the chemical, energy and industrial machinery sectors during the period 2005-2010. Findings - This study contributes to the literature in three ways. First, it incorporates literature on internationalization to study the possible connection between geographic international diversification and social performance in MNCs. Second, it sheds light on the debate between corporate social responsibility (CSR and the reputation of MNCs in a very diverse transnational context in which MNCs must meet the needs of stakeholders at both local and global levels. Third, it incorporates the mediating role of social performance in the relationship between geographic international diversification and the firm’s reputation. Originality/value - Prior studies have hardly analyzed this relationship, which becomes especially relevant for MNCs, since their implementation of advanced CSR practices in the different markets in which they operate will gain them a good reputation, not only in specific local contexts but also globally, benefitting the organization as a whole and enabling it to gain internal consistency (improvement in internal efficiency, transparency and legitimacy.

  15. The Impact of Digitalization on the Speed of Internationalization of Lean Global Startups

    Directory of Open Access Journals (Sweden)

    Michael Neubert

    2018-05-01

    Full Text Available Lean global startups need to internationalize early and fast. The digitalization of new foreign market development helps them to more efficiently identify new market opportunities in global markets. With this approach, they are saving resources while developing the most attractive markets. This article examines how lean global startups develop new foreign markets more rapidly due to digitalization. Thus, the aim is to understand the impact of digitalization on speed of internationalization of lean global startups. The study addresses a gap in the scholarly literature and a practical need to evaluate new foreign markets and business opportunities more quickly and more regularly and to understand what helps lean global startups react more quickly to opportunities and threats with respect to changing market attractiveness. Furthermore, it outlines why and how digitalization is important throughout the internationalization process. The research followed a multiple case-study design using different sources of evidence, including 73 interviews with senior managers of lean global startups. The findings reveal that digitalization allows lean global startups to increase decision-making efficiency and to optimize strategies and processes for evaluating international markets. The findings suggest that lean global startups can benefit from the use of digital technologies by applying a more efficient foreign market development process with regular reviews and a reduced workflow, by faster mediation between local market realities and strategic goals, by analyzing all foreign markets instead of just a sample of them, and by optimizing decision-making processes including the ability to make long-term, strategic decisions due to better market information.

  16. 40 CFR Appendix Vii to Part 266 - Health-Based Limits for Exclusion of Waste-Derived Residues*

    Science.gov (United States)

    2010-07-01

    ... Waste-Derived Residues* VII Appendix VII to Part 266 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR THE MANAGEMENT OF SPECIFIC HAZARDOUS WASTES AND SPECIFIC TYPES OF HAZARDOUS WASTE MANAGEMENT FACILITIES Pt. 266, App. VII Appendix VII to Part 266—Health...

  17. (99)Tc(VII) Retardation, Reduction, and Redox Rate Scaling in Naturally Reduced Sediments.

    Science.gov (United States)

    Liu, Yuanyuan; Liu, Chongxuan; Kukkadapu, Ravi K; McKinley, James P; Zachara, John; Plymale, Andrew E; Miller, Micah D; Varga, Tamas; Resch, Charles T

    2015-11-17

    An experimental and modeling study was conducted to investigate pertechnetate (Tc(VII)O4(-)) retardation, reduction, and rate scaling in three sediments from Ringold formation at U.S. Department of Energy's Hanford site, where (99)Tc is a major contaminant in groundwater. Tc(VII) was reduced in all the sediments in both batch reactors and diffusion columns, with a faster rate in a sediment containing a higher concentration of HCl-extractable Fe(II). Tc(VII) migration in the diffusion columns was reductively retarded with retardation degrees correlated with Tc(VII) reduction rates. The reduction rates were faster in the diffusion columns than those in the batch reactors, apparently influenced by the spatial distribution of redox-reactive minerals along transport paths that supplied Tc(VII). X-ray computed tomography and autoradiography were performed to identify the spatial locations of Tc(VII) reduction and transport paths in the sediments, and results generally confirmed the newly found behavior of reaction rate changes from batch to column. The results from this study implied that Tc(VII) migration can be reductively retarded at Hanford site with a retardation degree dependent on reactive Fe(II) content and its distribution in sediments. This study also demonstrated that an effective reaction rate may be faster in transport systems than that in well-mixed reactors.

  18. Prophylactic treatment of hereditary severe factor VII deficiency in pregnancy.

    Science.gov (United States)

    Pfrepper, Christian; Siegemund, Annelie; Hildebrandt, Sven; Kronberg, Juliane; Scholz, Ute; Niederwieser, Dietger

    2017-09-01

    : Severe hereditary factor VII deficiency is a rare bleeding disorder and may be associated with a severe bleeding phenotype. We describe a pregnancy in a 33-year-old woman with compound heterozygous factor VII deficiency and a history of severe menorrhagia and mucocutaneous bleedings. After discontinuation of contraceptives, menstruation was covered with recombinant activated factor VII (rFVIIa), and during pregnancy, rFVIIa had to be administered in first trimester in doses ranging from 15 to 90 μg/kg per day because of recurrent retroplacental hematomas and vaginal bleedings. Thrombin generation was measured in first trimester at different doses of rFVIIa and showed an increase in lag time when doses of less than 30 μg/kg/day were administered, whereas time to thrombin peak and peak thrombin were not influenced. A low-dose rFVIIa prophylactic treatment of 15 μg/kg every other day in the late second and in the third trimester was sufficient to allow a successful childbirth in this patient with severe factor VII deficiency.

  19. Positivity VII (Zaanen Centennial Conference)

    CERN Document Server

    Pagter, Ben; Gaans, Onno; Veraar, Mark

    2016-01-01

    This book presents the proceedings of Positivity VII, held from 22-26 July 2013, in Leiden, the Netherlands. Positivity is the mathematical field concerned with ordered structures and their applications in the broadest sense of the word. A biyearly series of conferences is devoted to presenting the latest developments in this lively and growing discipline. The lectures at the conference covered a broad spectrum of topics, ranging from order-theoretic approaches to stochastic processes, positive solutions of evolution equations and positive operators on vector lattices, to order structures in the context of algebras of operators on Hilbert spaces. The contributions in the book reflect this variety and appeal to university researchers in functional analysis, operator theory, measure and integration theory and operator algebras. Positivity VII was also the Zaanen Centennial Conference to mark the 100th birth year of Adriaan Cornelis Zaanen, who held the chair of Analysis in Leiden for more than 25 years and was ...

  20. Serendipitous Discovery of Factor VII Deficiency and the Ensuing Dilemma.

    Science.gov (United States)

    Umakanthan, Jayadev M; Dhakal, Prajwal; Gundabolu, Krishna; Koepsell, Scott A; Baljevic, Muhamed

    2018-03-01

    Congenital factor VII deficiency is a challenging disorder to manage, as it is associated with varied genotypes that do not clinically correlate with a bleeding phenotype. Individuals with severe factor VII deficiency (FVII: c 5%) may experience severe hemorrhages. In modern medicine, due to extensive routine pre-operative laboratory testing, clinically asymptomatic patients without any bleeding history might be incidentally discovered, raising clinical dilemmas. Careful consideration of bleeding versus thrombosis risk has to be made in such cases, especially in the elderly. Clinical history of no prior bleeding complications may be a reassuring factor. Minimal required replacement dosing of recombinant activated factor VII can be given peri-operatively in such situations, with close monitoring.

  1. 29 CFR 1604.8 - Relationship of title VII to the Equal Pay Act.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Relationship of title VII to the Equal Pay Act. 1604.8... GUIDELINES ON DISCRIMINATION BECAUSE OF SEX § 1604.8 Relationship of title VII to the Equal Pay Act. (a) The... based on the Equal Pay Act may be raised in a proceeding under title VII. (c) Where such a defense is...

  2. Pengelolaan Sumberdaya Air untuk Pengembangan Pariwisata di Pulau Pari, Kepulauan Seribu, DKI Jakarta

    Directory of Open Access Journals (Sweden)

    Roland Sinulingga

    2016-09-01

    Full Text Available ABSTRAK Penelitian bertujuan untuk (a menganalisis kondisi ketersediaan air di Pulau Pari, (b menganalisis kondisi kualitas air di Pulau Pari, (c menganalisis kebutuhan air dan proyeksinya untuk masa yang akan datang di Pulau Pari, dan (d merumuskan strategi pengelolaan sumberdaya air untuk pariwisata di Pulau Pari. Metode penelitian terdiri atas perhitungan neraca air, kebutuhan air, metode geometrik, analisis deskriptif, dan analisis SWOT. Pengambilan sampel air dan penduduk menggunakan metode purposive, sedangkan sampel wisatawan menggunakan metode accidental random sampling. Hasil akhir penelitian ketersediaan airtanah di Pulau Pari sebesar 290000,48 m3/tahun. Kualitas airtanah di lokasi penelitian tergolong baik. Besarnya kebutuhan air tahun 2013 sebesar 46381,947 m3/tahun. Pada tahun 2018 menjadi 54443,953 m3/tahun dan pada tahun 2023 mengalami peningkatan menjadi 63548,472 m3/tahun. Prioritas utama strategi pengelolaan sumberdaya air untuk pariwisata yaitu membuat kebijakan pembatasan pengunjung agar kelestarian pulau dan sumberdaya air tetap terjaga.   ABSTRACT This study aims to (a analyze water availability conditions in Pari Island, (b analyze the water quality conditions in Pari Island, (c analyze water demand and water projections for the future in Pari Island, and (d formulate strategies management water resources for tourism in Pari Island. The research method consists of the calculation of the water balance, water requirements, geometric methods, descriptive analysis, and SWOT analysis. Water sampling and settlement using purposive method, tourist’s samples using accidental random sampling. The final results of The amount of soil water availability in Pari Island of 290000,48 m3 / year. Groundwater quality in the study area are classified as good. The amount of water demand in 2013 amounted to 46381,947 m3 / year. In 2018 became 54443,953 m3 / year and in 2023 increased to 63548,472 m3 / year. First priority water resource

  3. Internationalizing Teacher Education: One University's Journey from Awareness to Action

    Science.gov (United States)

    Hansen, C. Bobbi

    2013-01-01

    In the 21st century, it is more important than ever to include global/international education as an essential component of teacher education programs. This paper showcases one Department of Education's journey to internationalize its teacher credential program. Components of the reform include: 1) shared conversations, 2) goal-setting, 3)…

  4. Internationalizing Medical Education: The Special Track Curriculum 'Global Health' at Justus Liebig University Giessen.

    Science.gov (United States)

    Knipper, Michael; Baumann, Adrian; Hofstetter, Christine; Korte, Rolf; Krawinkel, Michael

    2015-01-01

    Internationalizing higher education is considered to be a major goal for universities in Germany and many medical students aspire to include international experiences into their academic training. However, the exact meaning of "internationalizing" medical education is still poorly defined, just as is the possible pedagogic impact and effects. Against this background, this article presents the special track curriculum on global health (in German: Schwerpunktcurriculum Global Health, short: SPC) at Justus Liebig University Giessen, which was established in 2011 as a comprehensive teaching program to integrate international perspectives and activities systematically into the clinical years of the medical curriculum. The report of the structure, content, didactic principles and participants' evaluations of the SPC is embedded into a larger discussion of the pedagogic value of a broad and interdisciplinary perspective on "global health" in medical education, that explicitly includes attention for health inequities, social determinants of health and the cultural dimensions of medicine and health abroad and "at home" (e.g. in relation to migration). We conclude that if properly defined, the emerging field of "global health" represents a didactically meaningful approach for adding value to medical education through internationalizing the curriculum, especially in regard to themes that despite of their uncontested value are often rather weak within medical education. The concrete curricular structures, however, have always to be developed locally. The "SPC" at Giessen University Medical School is only one possible way of addressing these globally relevant issues in one particular local academic setting.

  5. Best practices of internationalization of the Higher Education in Asia-Pacific: The case of management of a double degree program

    Directory of Open Access Journals (Sweden)

    Félix Rogelio Flores

    2012-09-01

    Full Text Available The challenges of nations from Asia and the Pacific to create sustainable and economic spaces, have led their people to seek new educative mechanisms to forge from their childhood and youth, more competitive people, generators of wealth; as an example, China, Korea and India, being the internationalization the best example. This article presents a brief overview of the major events that have given way to new patterns of mobility and internationalization of Umap since its inception in 1993 until today. We present the case of the school of marketing in which outlines the learning, as a result of the institutional efforts of a double degree program with a University of the Umap program, this will allow to identify areas of prospect to establish improvements in an internationalization program of any Institution of higher education that aspire to any position in the global context.

  6. The German ''Energiewende''. Evaluation after the Paris-agreement; Die Deutsche Energiewende. Bewertung nach dem Klima-Abkommen von Paris

    Energy Technology Data Exchange (ETDEWEB)

    Roth, Eike

    2016-12-15

    The World-Climate-Summit 2016 in Paris agreed to exacerbated goals for climate protection. This paper will scrutinize whether Germany can comply with its Paris-obligations by continuing the ongoing German ''Energiewende''. The result is clear-cut: The German ''Energiewende'' is inadequate. Due to the cap-and-trade system of the EU the ''Energiewende'' can in no way contribute to climate protection.

  7. A virtual caravan--A metaphor for home-internationalization through social media: A qualitative content analysis.

    Science.gov (United States)

    Chan, Engle A; Nyback, Maj-Helen

    2015-06-01

    An internationalized curriculum in nursing education was created in response to the rise of globalization and the need to provide nursing care to people of diverse cultures. Through technology, internationalization at home can facilitate intercultural experiences for more nursing students. The aim of this study is to explore and describe how a virtual course in intercultural communication between students of two universities, through internationalization at home, can support the development of cultural competence. Qualitative research Junior year nursing students Qualitative content analysis of transcribed written and oral presentations during a course on intercultural communication. Four major themes, which are not mutually exclusive, were identified. Through this intercultural experience, without leaving home, students uncovered their cultural selves and others based on their own reflective understanding and collaborative discourse with each other and the use of social media for communication. Through experiential intercultural encounters beyond textbook and online materials, they learned to appreciate each other as people with cultural differences yet with much in common, and to recognize their assumptions and the value of subtleties and nuances. They were able to explore solutions within an unfamiliar context through their own efforts and with the support of peers and teachers. This led to a deeper understanding of cultural sensitivity and competence. Copyright © 2015 Elsevier Ltd. All rights reserved.

  8. EO-Performance relationships in Reverse Internationalization by Chinese Global Startup OEMs: Social Networks and Strategic Flexibility.

    Science.gov (United States)

    Chin, Tachia; Tsai, Sang-Bing; Fang, Kai; Zhu, Wenzhong; Yang, Dongjin; Liu, Ren-Huai; Tsuei, Richard Ting Chang

    2016-01-01

    Due to the context-sensitive nature of entrepreneurial orientation (EO), it is imperative to in-depth explore the EO-performance mechanism in China at its critical, specific stage of economic reform. Under the context of "reverse internationalization" by Chinese global startup original equipment manufacturers (OEMs), this paper aims to manifest the unique links and complicated interrelationships between the individual EO dimensions and firm performance. Using structural equation modeling, we found that during reverse internationalization, proactiveness is positively related to performance; risk taking is not statistically associated with performance; innovativeness is negatively related to performance. The proactiveness-performance relationship is mediated by Strategic flexibility and moderated by social networking relationships. The dynamic and complex institutional setting, coupled with the issues of overcapacity and rising labor cost in China may explain why our distinctive results occur. This research advances the understanding of how contingent factors (social network relationships and strategic flexibility) facilitate entrepreneurial firms to break down institutional barriers and reap the most from EO. It brings new insights into how Chinese global startup OEMs draw on EO to undertake reverse internationalization, responding the calls for unraveling the heterogeneous characteristics of EO sub-dimensions and for more contextually-embedded treatment of EO-performance associations.

  9. Manipulation of the membrane binding site of vitamin K-dependent proteins: Enhanced biological function of human factor VII

    OpenAIRE

    Shah, Amit M.; Kisiel, Walter; Foster, Donald C.; Nelsestuen, Gary L.

    1998-01-01

    Recent studies suggested that modification of the membrane contact site of vitamin K-dependent proteins may enhance the membrane affinity and function of members of this protein family. The properties of a factor VII mutant, factor VII-Q10E32, relative to wild-type factor VII (VII, containing P10K32), have been compared. Membrane affinity of VII-Q10E32 was about 20-fold higher than that of wild-type factor VII. The rate of autoactivation VII-Q10E32 with soluble tissue factor was 100-fold fast...

  10. Programs that Internationalize Nursing Curricula in Baccalaureate Schools of Nursing in the United States.

    Science.gov (United States)

    Lindquist, Gay J.

    1986-01-01

    Results of a national survey of baccalaureate nursing programs are presented concerning programs for study abroad, international exchange programs, and other approaches to internationalizing nursing curricula, including courses dealing with health care and nursing in foreign countries. (Author/MSE)

  11. Paris-Princeton lectures on mathematical finance 2010

    CERN Document Server

    Cousin, Areski; Guéant, Olivier; Hobson, David; Jeanblanc, Monique; Lasry, Jean-Michel; Laurent, Jean-Paul; Lions, Pierre-Louis; Tankov, Peter

    2011-01-01

    The Paris-Princeton Lectures on Mathematical Finance, of which this is the fourth volume, publish cutting-edge research in self-contained, expository articles from outstanding specialists - established or on the rise! The aim is to produce a series of articles that can serve as an introductory reference source for research in the field. The articles are the result of frequent exchanges between the finance and financial mathematics groups in Paris and Princeton. The present volume sets standards with articles by Areski Cousin, Monique Jeanblanc and Jean-Paul Laurent, Stéphane Crépey, Olivier Guéant, Jean-Michel Lasry and Pierre-Louis Lions, David Hobson, and Peter Tankov.

  12. Energy and Global Climate Change: The Road from Paris to Denver

    Energy Technology Data Exchange (ETDEWEB)

    Logan, Jeffrey

    2016-10-27

    This presentation provides an overview of the National Renewable Energy Laboratory; a snapshot of U.S. power sector transformation; a brief history of climate negotiations; an overview of the Paris Agreement; and what the Paris Agreement means for Colorado and beyond.

  13. Internationalization of Higher Education in University Institution Rankings: The Influence of National Culture

    Science.gov (United States)

    Delgado-Márquez, Blanca L.; Hurtado-Torres, Nuria E.; Bondar, Yaroslava

    2012-01-01

    Internationalization constitutes a widespread concept in the management literature and has recently begun to be applied to higher education institutions. While previous research has analyzed the relationship between national culture and corporate profit-oriented behavior, in this study, we focus on university institutions to investigate the…

  14. 76 FR 31892 - Recordkeeping and Reporting Requirements Under Title VII, the ADA, and GINA

    Science.gov (United States)

    2011-06-02

    ... Requirements Under Title VII, the ADA, and GINA AGENCY: Equal Employment Opportunity Commission. ACTION: Notice... Civil Rights Act of 1964 (Title VII) and the Americans with Disabilities Act (ADA) to entities covered... the same record retention requirements under GINA that are imposed under Title VII and the ADA, i.e...

  15. Rapid Internationalization of SMEs: Evidence from Born Global Firms in Chile

    Directory of Open Access Journals (Sweden)

    Christian A. Cancino

    2014-10-01

    Full Text Available The literature on born global firms in developed countries has revealed some factors that influence the rapid internationalization of Small and Medium Enterprises (SMEs, such as the technological level of the sector in which the firm participates, psychological and geographical distances from the target markets, and the existence of contact networks. To date, little research has been carried out on this topic for Latin American countries. This paper explores how certain determinants influence Chilean born global firms. A logistic regression model is used to analyze 112 SMEs with regular export activities. The results show that Chilean born global firms are influenced by national and international contact networks that their founders are able to generate. The psychological distance between Chilean SMEs and developed countries in Asia, North America and Europe also influences the internationalization of Chilean SMEs. The principal characteristic of Chilean born global firms is their lack of participation in highly technological sectors, with these SMEs instead being involved in sectors that actively exploit natural resources. The results of this study permit certain public policy recommendations to be made that might boost the development of export SMEs.

  16. Internationalization's effect on marketing learning: a study of Syrian firms

    OpenAIRE

    Ibeh, Kevin; Kasem, L.

    2014-01-01

    The aim of the present study is to understand the effects of international expansion on firms’ acquisition of marketing learning. This study’s focus on marketing learning complements previous research on the impact of internationalization on the development of foreign-market and technological knowledge. The research finds that the scope of a firm’s international activities, perception of gaps in marketing knowledge, and external social capital positively influence firms’ acquisition of market...

  17. Wendelstein VII-A in torsatron mode

    International Nuclear Information System (INIS)

    Harmeyer, E.; Kisslinger, J.; Rau, F.; Wobig, H.

    1985-03-01

    Variable shear - positive or negative, up to about 20 percent - can be introduced into the Wendelstein VII-A Stellarator vacuum field configuration by different currents in the two helix systems, and balancing the resulting vertical field. (orig.)

  18. The value of knowledge, network relationships and governmental support for chinese firms’ early internationalization

    DEFF Research Database (Denmark)

    Vissak, Tiia; Tsukanova, Tatyana; Zhang, Xiaotian

    2017-01-01

    Firms’ early internationalization has received considerable research attention. According to studies on born globals (Madsen and Servais 1997) and international new ventures (Oviatt and McDougall 1994), firms enter far markets soon after establishment. However, according to studies on slower...

  19. A multidimensional decision-making model for internationalization of high-tech SMEs in transition economics

    NARCIS (Netherlands)

    Roersen, M.J.; Roersen, Mariska; Groen, Arend J.; Kraaijenbrink, Jeroen

    2008-01-01

    Until now, international entrepreneurship has mainly used stage theory, institutional theory, transaction cost economics and the resource-based view to explain or describe the internationalization of SMEs in transition economy context. Following recent literature we contend that these approaches are

  20. The Internationalization of Software Development Subcontractors: A Nordic Perspective on What We Know and What We Need to Know

    DEFF Research Database (Denmark)

    Skaates, Maria Anne

    2003-01-01

    As part of a research project, which will encompass in-depth case studies of small Nordic software development subcontractors' work for large, foreign software corporations, the dynamics of the initial phases of the subcontractors' internationalization will be examined. Because high-tech firms from...... framework for the study. It starts with a look at the Nordic perspective on this issue as well as a brief review of existing literature on service firms', software firms' and SMEs' internationalization, before going on to elucidate and justify the study's eleven research questions. Thereafter relevant...

  1. Faktor-faktor Yang Memengaruhi Produksi Gula PTPN VII (Persero)

    OpenAIRE

    Savitri, Rizky; Widyastutik, Widyastutik

    2013-01-01

    This study aimed to analyze the influence of the level of sugar cane yield, labor, production process period, and supporting materials on the production of PTPN VII (Persero) PG. Cinta Manis, as well as analyzing the elasticity of production and business scale of PTPN VII (Persero) PG. Cinta Manis. The method used to analyze the data were quantitative analysis of Cobb Douglas production function with ordinary least square method to observe variable influences of PG. Cinta Manis sugar product...

  2. The Internationalization Process of International New Ventures: The Case of Skype

    OpenAIRE

    Chan, Cheuk-Hay

    2007-01-01

    Past literature has emphasized on large, long-established multinational enterprises (MNEs) in international business. However, the emerging phenomenon of international new ventures has attracted much attention due to their distinctive internationalization processes. Skype Technologies S.A. is one of these international new ventures with comparable characteristics, albeit it has shown differences compared with the typical international new ventures. This research aims to compare and contrast t...

  3. INTERNATIONALIZATION AND REGIONALIZATION OF CORPORATE MANAGEMENT PRACTICES OF COMPANIES IN ROMANIA

    OpenAIRE

    Maria GÂF-DEAC; Petru ROŞCA,

    2015-01-01

    In article it is recognized the advantages of internationalization and regionalization of companies and as such, managers and corporate directories of modern companies give its alternative to develop best management practices in the field. Indicators, performance indicators and key performance indicators identified and selected in the context investigated, showing commitment still low (unsatisfactory to satisfactory) Romanian firms in the positioning or repositioning in regional corporate ar...

  4. Coagulation factor VII is regulated by androgen receptor in breast cancer.

    Science.gov (United States)

    Naderi, Ali

    2015-02-01

    Androgen receptor (AR) is widely expressed in breast cancer; however, there is limited information on the key molecular functions and gene targets of AR in this disease. In this study, gene expression data from a cohort of 52 breast cancer cell lines was analyzed to identify a network of AR co-expressed genes. A total of 300 genes, which were significantly enriched for cell cycle and metabolic functions, showed absolute correlation coefficients (|CC|) of more than 0.5 with AR expression across the dataset. In this network, a subset of 35 "AR-signature" genes were highly co-expressed with AR (|CC|>0.6) that included transcriptional regulators PATZ1, NFATC4, and SPDEF. Furthermore, gene encoding coagulation factor VII (F7) demonstrated the closest expression pattern with AR (CC=0.716) in the dataset and factor VII protein expression was significantly associated to that of AR in a cohort of 209 breast tumors. Moreover, functional studies demonstrated that AR activation results in the induction of factor VII expression at both transcript and protein levels and AR directly binds to a proximal region of F7 promoter in breast cancer cells. Importantly, AR activation in breast cancer cells induced endogenous factor VII activity to convert factor X to Xa in conjunction with tissue factor. In summary, F7 is a novel AR target gene and AR activation regulates the ectopic expression and activity of factor VII in breast cancer cells. These findings have functional implications in the pathobiology of thromboembolic events and regulation of factor VII/tissue factor signaling in breast cancer. Copyright © 2014 Elsevier Inc. All rights reserved.

  5. The internationalization of the Korean radiological society

    International Nuclear Information System (INIS)

    Choi, Byung Ihn; Kim, Seung Hyup; Han, Man Chung; Kim, Young Goo; Kim, Kun Sang

    1995-01-01

    Toward the beginning of the twenty-first century, the world experiences the dramatic changes in politics, economics and culture, and it is evident that the Korean medical field will not be able to survive provided it doesn't prepare ourselves to adapt to those changes. The Korean Medical Society held a forum for the active operation of the medical society, inviting several leading affiliated societies, to meet the needs of the times. This review describes the summary of the presentation that the authors made on behalf of the Korean Radiological Society in the forum, including the organization, current status of academic activity, current status of international communication, and problems encountered in the internationalization of the Korean Radiological Society

  6. Research on the Internationalization and the Localization of China's MBA Education

    Science.gov (United States)

    Lin, Jie; Ma, Haiyong

    2012-01-01

    This article started with a brief review of the history and current situation of Chinese MBA education and its internationalization and localization. Then, the author presented the opportunities faced of China's MBA education. Furthermore, the challenges faced by Chinese MBA education in the globalization process together with their implications…

  7. Paris 2000 researches and men; Paris 2000 des recherches et des hommes

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    The IWA and ISWA congresses organized in Paris in july showed the latest research developments in the field of water and wastes management. The water sector is more mature than the waste sector but for both a closer association of the public and private is increasing. A summary of the presentations in successively the water and the wastes management is proposed bringing an analysis of the international situation and regulations. (A.L.B.)

  8. Photosynthetic pigments of oceanic Chlorophyta belonging to prasinophytes clade VII.

    Science.gov (United States)

    Lopes Dos Santos, Adriana; Gourvil, Priscillia; Rodríguez, Francisco; Garrido, José Luis; Vaulot, Daniel

    2016-02-01

    The ecological importance and diversity of pico/nanoplanktonic algae remains poorly studied in marine waters, in part because many are tiny and without distinctive morphological features. Amongst green algae, Mamiellophyceae such as Micromonas or Bathycoccus are dominant in coastal waters while prasinophytes clade VII, yet not formerly described, appear to be major players in open oceanic waters. The pigment composition of 14 strains representative of different subclades of clade VII was analyzed using a method that improves the separation of loroxanthin and neoxanthin. All the prasinophytes clade VII analyzed here showed a pigment composition similar to that previously reported for RCC287 corresponding to pigment group prasino-2A. However, we detected in addition astaxanthin for which it is the first report in prasinophytes. Among the strains analyzed, the pigment signature is qualitatively similar within subclades A and B. By contrast, RCC3402 from subclade C (Picocystis) lacks loroxanthin, astaxanthin, and antheraxanthin but contains alloxanthin, diatoxanthin, and monadoxanthin that are usually found in diatoms or cryptophytes. For subclades A and B, loroxanthin was lowest at highest light irradiance suggesting a light-harvesting role of this pigment in clade VII as in Tetraselmis. © 2015 Phycological Society of America.

  9. 76 FR 79065 - Recordkeeping and Reporting Requirements Under Title VII, the ADA and GINA

    Science.gov (United States)

    2011-12-21

    ... Reporting Requirements Under Title VII, the ADA and GINA CFR Correction In Title 29 of the Code of Federal... title VII or section 107 of the ADA'' and add in their place the words ``section 709(c) of title VII, section 107 of the ADA, or section 207(a) of GINA'' wherever they appear in the following sections...

  10. ENHANCING THE INTERNATIONALIZATION OF THE GLOBAL INSURANCE MARKET: CHANGING DRIVERS OF MERGERS AND ACQUISITIONS

    Directory of Open Access Journals (Sweden)

    D. Rasshyvalov

    2014-03-01

    Full Text Available One-third of worldwide mergers and acquisitions involving firms from different countries make M&A one of the key drivers of internationalization. Over the past five years insurance cross-border merger and acquisition activities have globally paralleled deep financial crisis.

  11. Tissue Factor–Factor VII Complex As a Key Regulator of Ovarian Cancer Phenotypes

    OpenAIRE

    Koizume, Shiro; Miyagi, Yohei

    2015-01-01

    Tissue factor (TF) is an integral membrane protein widely expressed in normal human cells. Blood coagulation factor VII (fVII) is a key enzyme in the extrinsic coagulation cascade that is predominantly secreted by hepatocytes and released into the bloodstream. The TF–fVII complex is aberrantly expressed on the surface of cancer cells, including ovarian cancer cells. This procoagulant complex can initiate intracellular signaling mechanisms, resulting in malignant phenotypes. Cancer tissues are...

  12. The internationalization of nuclear safety

    International Nuclear Information System (INIS)

    Rosen, M.

    1989-01-01

    Nuclear safety is interlinked in many ways with the themes of this conference. In searching for co-operative activities that touch on global energy and environmental problems and on initiatives that relieve international tensions, the ongoing developments in nuclear power safety offer a number of successful examples. Commercial nuclear power has been with us for more than 30 years, and with 26 countries operating plants in addition to 6 more constructing their first, there has been an ongoing global co-operation, coinciding of Chernobyl with Glasnost, along with the increasing awareness of the benefits of common solutions to safety issues, have brought about an internationalization of nuclear safety. Although the main responsibility for safety rests with each operator and its government, a primary driving force expanding international co-operation is the transboundary aspects of nuclear energy, as vividly demonstrated by Chernobyl accident. In this presentation we focus on the mechanisms already in place that foster cooperation in the nuclear safety area

  13. Globalization VS Internationalization for Entrepreneurs

    Directory of Open Access Journals (Sweden)

    Bambang Pratama

    2011-05-01

    Full Text Available In an article in the Harvard Business Review Theodore Levitt published The Globalization of Markets. Business activities across the country after it became a very interesting topic of study for both academics and practitioners. This topic has become so phenomenal because his arguments about globalization is the economic convergence with business activities without any national barriers. In contrast to the internationalization that tends to narrow and tends to do business across national borders. Central idea must answered by manager and entrepreneurs is whether your market global or international. Before answering them it requires understanding and a new paradigm on this matter. Furthermore, Thomas Friedman in his book "The world is flat" also reinforces Levitt idea and prescript a world with evolution of information and technology. This new economic eras opened new opportunity on entrepreneur point of view. There is wide open door to enter global market and more easy to accelerate company growth or new business start-up. 

  14. Järgmisena Kremli sihikul internet / Krister Paris

    Index Scriptorium Estoniae

    Paris, Krister, 1977-

    2008-01-01

    Venemaa infotehnoloogiate ja sideministeeriumi määrusest, mis nõuab telekommunikatsioonifirmadelt ning internetiteenuse pakkujatelt ligipääsu kogu neid läbivale sidele. Lisatud: netisõlm viis kohtu alla

  15. What Drives Rapid Internationalization – A Case of Malaysian SMEs

    OpenAIRE

    Saqib, Sahabat

    2008-01-01

    Traditionally, internationalization has been assumed to be activity that requires significant amounts of time and resources. Owing to this, firms took time to establish themselves in their domestic markets before they started to expand into overseas markets. However, over the past decade or so numerous small and medium firms have sprung up, these companies have a global orientation right from their inception. These firms have been termed Born Globals. In light of the aforementioned, this diss...

  16. Part 6. Internationalization and collocation of FBR fuel cycle facilities

    International Nuclear Information System (INIS)

    Stevenson, M.G.; Abramson, P.B.; LeSage, L.G.

    1980-01-01

    This report examines some of the non-proliferation, technical, and institutional aspects of internationalization and/or collocation of major facilities of the Fast Breeder Reactor (FBR) fuel cycle. The national incentives and disincentives for establishment of FBR Fuel Cycle Centers are enumerated. The technical, legal, and administrative considerations in determining the feasibility of FBR Fuel Cycle Centers are addressed by making comparisons with Light Water Reactor (LWR) centers which have been studied in detail by the IAEA and UNSRC

  17. Resbuffling of the electric power industries: internationalization new players, diversification

    International Nuclear Information System (INIS)

    Chevalier, J.M.; Salaun, D.

    1995-01-01

    The changes that are being brought in the forms of organization of the power industry lead to a global restructuring of the industry. Traditional players are forced to redefine their strategies concerning vertical and horizontal integration and also diversification. They tend to internationalize their business but they are facing aggressive new-comers. The future structure of the industry is not yet determined but there will be a great number of very different corporate players. (authors). 1 fig

  18. Bye-Bye Teacher-Scholar, Hello Teacher-Scholar? Possibilities and Perils of Comprehensive Internationalization

    Science.gov (United States)

    Elliott, Dawn Richards

    2017-01-01

    This article develops the claim that the Teacher-Scholar Model (TS), which is used by Institutions of Higher Learning (IHL) to evaluate faculty worktime, is ill-suited for the strategy of comprehensive internationalization (CI). CI aims to enhance global learning by offering academic and non-academic opportunities for greater student engagement…

  19. Messier, Copernicus, Flamsteed: The SAF Rare-Book Collection in Paris

    Science.gov (United States)

    Pasachoff, Jay M.

    2014-01-01

    The historic books belonging to the Société Astronomique de France, founded by Camille Flammarion in 1887, are located partly in Paris and partly at the Flammarion site in Juvisy, a Paris suburb. Their holdings include first editions of Copernicus's De Revolutionibus and of Flamsteed's star atlas, as well as Messier's own copy of his 1783 and 1784 papers with his handwritten comments and additions. I will describe the fruitless search for a Bevis atlas and the circumstances that led me to inspect these treasures. I thank David Valls-Gabaud and Philippe Morel of the Société Astronomique de France for their hospitality in Paris, Jean-Claude Pecker, and Owen Gingerich for his prior work on Messier's catalogue.

  20. Porphyry of Russian Empires in Paris

    Science.gov (United States)

    Bulakh, Andrey

    2014-05-01

    Porphyry of Russian Empires in Paris A. G. Bulakh (St Petersburg State University, Russia) So called "Schokhan porphyry" from Lake Onega, Russia, belongs surely to stones of World cultural heritage. One can see this "porphyry" at facades of a lovely palace of Pavel I and in pedestal of the monument after Nicolas I in St Petersburg. There are many other cases of using this stone in Russia. In Paris, sarcophagus of Napoleon I Bonaparte is constructed of blocks of this stone. Really, it is Proterozoic quartzite. Geology situation, petrography and mineralogical characteristic will be reported too. Comparison with antique porphyre from the Egyptian Province of the Roma Empire is given. References: 1) A.G.Bulakh, N.B.Abakumova, J.V.Romanovsky. St Petersburg: a History in Stone. 2010. Print House of St Petersburg State University. 173 p.

  1. Coagulation factor VII, serum-triglycerides and the R/Q353 polymorphism: differences between older men and women

    NARCIS (Netherlands)

    Mennen, L. I.; de Maat, M. P.; Schouten, E. G.; Kluft, C.; de Jong, P. T.; Hofman, A.; Grobbee, D. E.

    1997-01-01

    Coagulation factor VII activity (FVII:C) is a risk indicator for cardiovascular disease. It is related to serum-triglycerides and the R/Q353 polymorphism (alleles R and Q) in the gene coding for factor VII is strongly associated with factor VII. The association of serum-triglycerides with factor VII

  2. The influence of experiential, inherited and external knowledge on the internationalization of venture capital firms

    NARCIS (Netherlands)

    S. De Prijcker (Sofie); S. Manigart (Sophie); D.M. Wright (Mike); W. de Maeseneire (Wouter)

    2012-01-01

    textabstractThis paper examines the effect of different types of international knowledge accumulation on the internationalization of venture capital firms, as a particular type of professional service firms. We distinguish between experiential knowledge acquired through previous activities,

  3. THE INTERNATIONALIZATION OF HIGHER EDUCATION: AN EMERGING POLITICAL AGENDA

    Directory of Open Access Journals (Sweden)

    Malcolm McVicar

    2015-01-01

    Full Text Available Given growing importance of education as a factor of internal development and in the context of globalization universities can be considered to be international economic actors playing an increasingly significant role in economic and political agenda. Universities face a lot of challenges, to wit: quality control, further privatization of higher education and for-profit education, the problem of innovations and advanced technologies, the emergence of international labour market etc. Therefore internationalization of higher education determines the necessity to reform and adapt universities around the globe.

  4. Inward-outward linkages in the internationalization process of firms

    DEFF Research Database (Denmark)

    Choquette, Eliane

    , on the one hand, that firms with importing experience from a specific market prior to initiating exports to this market have a shorter export spell. This in line with the thesis that prior importing experience facilitates firms’ outward internationalization by reducing the sunk costs associated with export...... market entry and that export survival is negatively correlated with these sunk costs. Only importing experience within the same market affects (shortens) a firm’s export spell, which also is in line with the argument that a priori import experience reduces firms’ export market specific sunk costs...

  5. Internationalization Policies of Jesuit Universities: A Case Study of Japan and the U.S

    Science.gov (United States)

    Jung, Kang-Yup

    2009-01-01

    In the wake of globalization, higher education institutions almost inevitably have adopted and implemented internationalization policies as their primary strategy for responding to the challenges and opportunities brought about by globalization. This study concerns the comparison of the motivations, program strategies, and organization strategies…

  6. Internationalization as a strategy to overcome industry barriers-An assessment of the marine energy industry

    International Nuclear Information System (INIS)

    Lovdal, Nicolai; Neumann, Frank

    2011-01-01

    Research on conditions to develop new innovations within emerging renewable energy industries is often done with a national focus. However, recent research on international entrepreneurship has revealed that firms operate on international levels very early in their life time. Thus, based on former research on international entrepreneurship and case examples, we build the propositions that firms in the marine energy industry use internationalization as a strategy to overcome industry barriers. Our primary source of data is a unique dataset from a global survey of all the companies in the marine energy industry who are aiming to commercialize a wave or tidal energy device. This paper is organized in two steps: first we identified the most challenging industry barriers perceived by companies. Second we use these to form propositions which we assess through empirical data. The two most challenging barriers perceived by the companies are need for capital and need for supportive political schemes. Our findings reveal that internationalization certainly is a common strategy to access capital and attractive support schemes in foreign countries. The early internationalization has implications for researchers, managers and policy makers. - Research highlights: → Industry barriers identified as access to capital and supportive political schemes. → International entrepreneurship is used to overcome industry barriers. → Start-ups in emerging energy industries 'shop' national support schemes. → Future research to provide policy advice should adapt to the international reality. → Research based on a worldwide survey of wave and tidal energy device developers.

  7. Internationalization as a strategy to overcome industry barriers-An assessment of the marine energy industry

    Energy Technology Data Exchange (ETDEWEB)

    Lovdal, Nicolai, E-mail: nicolai.lovdal@iot.ntnu.n [Industrial Economics and Technology Management, Norwegian University of Science and Technology, 7491 Trondheim (Norway); Neumann, Frank, E-mail: frank@wave-energy-centre.or [Wave Energy Centre, Av. Manuel Maia, 36, r/c Dto., 1000-201 Lisboa (Portugal)

    2011-03-15

    Research on conditions to develop new innovations within emerging renewable energy industries is often done with a national focus. However, recent research on international entrepreneurship has revealed that firms operate on international levels very early in their life time. Thus, based on former research on international entrepreneurship and case examples, we build the propositions that firms in the marine energy industry use internationalization as a strategy to overcome industry barriers. Our primary source of data is a unique dataset from a global survey of all the companies in the marine energy industry who are aiming to commercialize a wave or tidal energy device. This paper is organized in two steps: first we identified the most challenging industry barriers perceived by companies. Second we use these to form propositions which we assess through empirical data. The two most challenging barriers perceived by the companies are need for capital and need for supportive political schemes. Our findings reveal that internationalization certainly is a common strategy to access capital and attractive support schemes in foreign countries. The early internationalization has implications for researchers, managers and policy makers. - Research highlights: {yields} Industry barriers identified as access to capital and supportive political schemes. {yields} International entrepreneurship is used to overcome industry barriers. {yields} Start-ups in emerging energy industries 'shop' national support schemes. {yields} Future research to provide policy advice should adapt to the international reality. {yields} Research based on a worldwide survey of wave and tidal energy device developers.

  8. Self-production of tissue factor-coagulation factor VII complex by ovarian cancer cells

    OpenAIRE

    Yokota, N; Koizume, S; Miyagi, E; Hirahara, F; Nakamura, Y; Kikuchi, K; Ruf, W; Sakuma, Y; Tsuchiya, E; Miyagi, Y

    2009-01-01

    Background: Thromboembolic events are a major complication in ovarian cancer patients. Tissue factor (TF) is frequently overexpressed in ovarian cancer tissue and correlates with intravascular thrombosis. TF binds to coagulation factor VII (fVII), changing it to its active form, fVIIa. This leads to activation of the extrinsic coagulation cascade. fVII is produced by the liver and believed to be supplied from blood plasma at the site of coagulation. However, we recently showed that ovarian ca...

  9. [History of the Journées Dermatologiques de Paris].

    Science.gov (United States)

    Tilles, G

    2013-12-01

    Founded in 1801 at the Hôpital Saint-Louis, Paris, under Jean-Louis Alibert, the French School of Dermatology was initially structured around the French Society of Dermatology (1889) and the organization of two world congresses (Paris 1889, 1900). After World War I, the creation of dermatological societies in the provinces infused French dermatology with new energy. In 1922, the first congress of the French-speaking dermatologists further contributed to the public profile of dermatologists in France. The "Journées de Mars" were initiated in 1961 at the Hôpital Saint-Louis, and in 1975 they went on to become the "Journées dermatologiques de Paris". Pr. Jean Civatte played a key role in their creation and in their organization for 30 years. After 1979, since actual patients could no longer be presented, the organizers of the congress had to change the content of the meeting from clinical presentations to post-graduate teaching and clinical research. From its origins in the form of meetings of French dermatologists in an intimate setting at the Hôpital Saint-Louis, the "Journées dermatologiques de Paris" grew within the ensuing decades into a major scientific event of the French-speaking dermatological community, bringing together more than 4000 participants in December each year. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

  10. The marketing-sales organizations as the way of internationalizing of the small and medium enterprises

    Directory of Open Access Journals (Sweden)

    Piorunowska-Kokoszko Joanna

    2016-12-01

    Full Text Available The internationalization is becoming a part of company’s strategy, requiring some effort for getting its success. The present article is aimed at showing that joining the sale group is one of many ways of internationalizing activity for small and medium enterprises. The article presents the roles of sales group activity, its typical structure and opportunities and threats for its functioning. Based on collected data it was pointed, that companies, especially SME should analyze perspective for joining the sale group in their supply chain or seek for other forms of cooperation supporting their foreign market entry. Cooperation allows in relatively short time to achieve first results. Resignation of cooperation should be a conscious decision of management. Such decision, as every one, can bring expected benefits or be difficult to reconstruct it in the future.

  11. A Case Study of Issues of Strategy Implementation in Internationalization of Higher Education

    Science.gov (United States)

    Jiang, Nan; Carpenter, Victoria

    2013-01-01

    Purpose: The purpose of this research is to identify and critically evaluate key issues faced by an institution in the quest to implement higher education internationalization. Design/methodology/approach: A qualitative research is conducted in a post-1992 UK university. A total of 20 interviewees from three key departments participated in this…

  12. Faculty Transformation in Curriculum Transformation: The Role of Faculty Development in Campus Internationalization

    Science.gov (United States)

    Niehaus, Elizabeth; Williams, Letitia

    2016-01-01

    Curriculum transformation is often cited as one of the key strategies for internationalizing higher education in the United States, and faculty members play a central role in this process. The purpose of the study we report here was to explore the potential for professional development initiatives to foster the transformation in perspectives…

  13. The internationalization of the technological activities in the energy industries; L'internationalisation des activites technologiques dans les industries energetiques

    Energy Technology Data Exchange (ETDEWEB)

    Bourgeois, B [Institut d' Economie et de Politique de l' Energie - IEPE-CNRS/ Universite Pierre Mendes-France, 38 - Grenoble (France); Jacquier-Roux, V [Institut de Recherche Economique sur la Production et le Developpement -IREPD, 38 - Grenoble (France)

    2001-06-01

    This analysis of the technological internationalization factors is defined in five chapters. The first chapter deals with the evolutionist representation of the internationalization process of the technological activities of the firms. The chapter two is an historical synthesis from 1985 to 2000, of the industrial dynamics and of the technological strategies of the petroleum and electric power industries. The chapter three details the empirical method used to verify the hypothesis. Chapter four exposes the data analysis results of the patents of the sampled firms. The last chapter is devoted to the results interpretation. (A.L.B.)

  14. Repositioning Strategy for Malaysian Companies Internationalization

    Directory of Open Access Journals (Sweden)

    Ismi Rajiani

    2013-04-01

    Full Text Available The rise of the emerging-market countries offers both developing and developed countries a unique opportunity to gain the benefits of a truly international economy. Consequently, it is imper- ative to advance our knowledge of emerging-market countries MNC emergence and competitive- ness including Malaysian firms on how will they position their products strategically. Based on the framework of Porter’s Generic Strategy, this paper is composed of price/ volume segments and im- pacts on product strategy theory. The aim is to identify crucial triggering cues and focus areas for Malaysian companies and measure what role these play in different segments. This study argues that some Malaysian companies will reposition themselves strategically when internationalizing and that they will focus on other factors or triggering cues when doing so not merely adapting the prevalent price leadership strategy.

  15. Factor VII deficiency: a novel missense variant and genotype-phenotype correlation in patients from Southern Italy.

    Science.gov (United States)

    Tiscia, Giovanni; Favuzzi, Giovanni; Chinni, Elena; Colaizzo, Donatella; Fischetti, Lucia; Intrieri, Mariano; Margaglione, Maurizio; Grandone, Elvira

    2017-01-01

    This study aimed at attempting to correlate genotype and phenotype in factor VII deficiency. Here, we present molecular and clinical findings of 10 patients with factor VII deficiency. From 2013 to 2016, 10 subjects were referred to our center because of a prolonged prothrombin time identified during routine or presurgery examinations or after a laboratory assessment of a bleeding episode. Mutation characterization was performed using the bioinformatics applications PROMO, SIFT, and Polyphen-2. Structural changes in the factor VII protein were analyzed using the SPDB viewer tool. Of the 10 variants we identified, 1 was responsible for a novel missense change (c.1199G>C, p.Cys400Ser); in 2 cases we identified the c.-54G>A and c.509G>A (p.Arg170His) polymorphic variants in the 5'-upstream region of the factor VII gene and exon 6, respectively. To our knowledge, neither of these polymorphic variants has been described previously in factor VII-deficient patients. In silico predictions showed differences in binding sites for transcription factors caused by the c.-54G>A variant and a probable damaging effect of the p.Cys400Ser missense change on factor VII active conformation, leading to breaking of the Cys400-Cys428 disulfide bridge. Our findings further suggest that, independently of factor VII levels and of variants potentially affecting factor VII levels, environmental factors, e.g., trauma, could heavily influence the clinical phenotype of factor VII-deficient patients.

  16. Self-production of tissue factor-coagulation factor VII complex by ovarian cancer cells.

    Science.gov (United States)

    Yokota, N; Koizume, S; Miyagi, E; Hirahara, F; Nakamura, Y; Kikuchi, K; Ruf, W; Sakuma, Y; Tsuchiya, E; Miyagi, Y

    2009-12-15

    Thromboembolic events are a major complication in ovarian cancer patients. Tissue factor (TF) is frequently overexpressed in ovarian cancer tissue and correlates with intravascular thrombosis. TF binds to coagulation factor VII (fVII), changing it to its active form, fVIIa. This leads to activation of the extrinsic coagulation cascade. fVII is produced by the liver and believed to be supplied from blood plasma at the site of coagulation. However, we recently showed that ovarian cancer cells express fVII transcripts under normoxia and that this transcription is inducible under hypoxia. These findings led us to hypothesise that ovarian cancer cells are intrinsically associated with TF-fVIIa coagulation activity, which could result in thrombosis. In this study, we examined whether ectopically expressed fVII could cause thrombosis by means of immunohistochemistry, RT-PCR, western blotting and flow cytometry. Ectopic fVII expression occurs frequently in ovarian cancers, particularly in clear cell carcinoma. We further showed that ovarian cancer cells express TF-fVIIa on the cell surface under normoxia and that this procoagulant activity is enhanced by hypoxic stimuli. Moreover, we showed that ovarian cancer cells secrete microparticles (MPs) with TF-fVIIa activity. Production of this procoagulant secretion is enhanced under hypoxia. These results raise the possibility that cancer cell-derived TF-fVIIa could cause thrombotic events in ovarian cancer patients.

  17. USA Withdrawal from Paris Agreement – What Next?

    OpenAIRE

    Sergey Chestnoy; Dinara Gershinkova

    2017-01-01

    In June 2017, President Trump announced the USA’s withdrawal from the Paris Climate Accord, which had been ratified for less than a year, thanks in large part to the USA. That drastic shift followed the change in residency at the White House. Withdrawing from the Paris Accord presents an interesting topic for analysis. There’s the practical side of the withdrawal procedure as set out in Article 28 of the agreement, not to mention the consequences of US non-participation in address...

  18. A Cost-based Explanation of Gradual, Regional Internationalization of Multinationals on Social Networking Sites

    DEFF Research Database (Denmark)

    Pogrebnyakov, Nicolai

    2017-01-01

    of internationalization. Data on 5827 country pages of 240 multinational firms on Facebook, the most popular SNS today, is used. Creating a foreign country-specific Facebook page is considered the SNS equivalent of opening a physical subsidiary in that country. The data show that multinationals exhibit...

  19. Franchising as a method of internationalization of business activities

    OpenAIRE

    Asmalovskyy, Oleksandr

    2013-01-01

    The aim of this work is to evaluate franchising as a form of internationalization of business activities of small and medium enterprises and its effectiveness. Then define market sectors in which this method can be applied and analyze current situation of franchising on Czech and world markets. The work also focuses on idle segments of the Czech market. In conclusion, I would like to determine whether franchising may have strong development prospects in the Czech Republic and the world in fut...

  20. IMS LD. Paris Conference, April 2005

    NARCIS (Netherlands)

    Burgos, Daniel

    2005-01-01

    3 presentations run in Paris, France, in Apri 1st, 2005, in the Cité des Sciences, sponsored by UNFOLD Project and l'AFNOR about the following topics: - Update on UNFOLD CoP Valkenburg meeting 2005 - Creating a UoL - Introducing CopperCore

  1. Polyp Morphology: An Interobserver Evaluation for the Paris Classification Among International Experts

    NARCIS (Netherlands)

    van Doorn, Sascha C.; Hazewinkel, Y.; East, James E.; van Leerdam, Monique E.; Rastogi, Amit; Pellisé, Maria; Sanduleanu-Dascalescu, Silvia; Bastiaansen, Barbara A. J.; Fockens, Paul; Dekker, Evelien

    2015-01-01

    OBJECTIVES: The Paris classification is an international classification system for describing polyp morphology. Thus far, the validity and reproducibility of this classification have not been assessed. We aimed to determine the interobserver agreement for the Paris classification among seven Western

  2. Internationalization of Higher Education in Africa: Developments, Emerging Trends, Issues and Policy Implications

    Science.gov (United States)

    Jowi, James Otieno

    2009-01-01

    Higher education the world over has now become part of the globalization process and can no longer be strictly viewed from a national context. The realities of internationalization of higher education and its attendant impacts on the sector is an urgent priority for higher education, especially in developing economies such as Africa. This paper…

  3. The Biosphere Under Potential Paris Outcomes

    Science.gov (United States)

    Ostberg, Sebastian; Boysen, Lena R.; Schaphoff, Sibyll; Lucht, Wolfgang; Gerten, Dieter

    2018-01-01

    Rapid economic and population growth over the last centuries have started to push the Earth out of its Holocene state into the Anthropocene. In this new era, ecosystems across the globe face mounting dual pressure from human land use change (LUC) and climate change (CC). With the Paris Agreement, the international community has committed to holding global warming below 2°C above preindustrial levels, yet current pledges by countries to reduce greenhouse gas emissions appear insufficient to achieve that goal. At the same time, the sustainable development goals strive to reduce inequalities between countries and provide sufficient food, feed, and clean energy to a growing world population likely to reach more than 9 billion by 2050. Here, we present a macro-scale analysis of the projected impacts of both CC and LUC on the terrestrial biosphere over the 21st century using the Representative Concentration Pathways (RCPs) to illustrate possible trajectories following the Paris Agreement. We find that CC may cause major impacts in landscapes covering between 16% and 65% of the global ice-free land surface by the end of the century, depending on the success or failure of achieving the Paris goal. Accounting for LUC impacts in addition, this number increases to 38%-80%. Thus, CC will likely replace LUC as the major driver of ecosystem change unless global warming can be limited to well below 2°C. We also find a substantial risk that impacts of agricultural expansion may offset some of the benefits of ambitious climate protection for ecosystems.

  4. Housing and the construction of the city: the Paris Habitat Experience

    Directory of Open Access Journals (Sweden)

    Javier Arpa

    2015-12-01

    Full Text Available In Paris, the history and the evolution of social housing provision merge with those of a centennial institution. Created in 1914, the Office Public d’Habitations à Bon Marché, currently called Paris Habitat, manages more than 1,200 operations, 120,000 housing units inhabited by 200,000 residents. This article reviews an investigation to this exceptional heritage commissioned by the Pavillon de l'Arsenal in Paris, which resulted in the exhibition and catalogue Paris Habitat: Cent ans de ville, cent ans de vie, presented by the institution in 2015.The investigation, exhibition and publication were organized around the analysis of ten fragments of reality that, rather than matching administrative divisions or urban planning projects, span municipalities, districts and infrastructures. From low-cost to large-scale housing, from concerns with hygiene to ecology issues, each one of the building ensembles analyzed bears witness to the will to change society through housing. Written by the project’s main curator and catalogue editor, this review details the process through which essential questions formulated early on – What is the city we want like? How is it built? – were answered to: selecting from the wealth of material produced by Paris Habitat over one hundred years of activity, the team exposed their political stance on urban strategies at large. Importantly, Paris Habitat’s ‘actions’ substantiated the team’s belief that our knowledge of this long, continuous urban experiment can contribute to improve the metropolises of today and strengthen its ability to answer contemporary concerns: the transformation of offices into housing, new residents’ participation formulas, new building and conception processes, which are key elements in the making of cities that need to be dense, diverse, intense, fertile and agile.

  5. Effect of Paris saponin on antitumor and immune function in U14 ...

    African Journals Online (AJOL)

    bearing mice, and reduced the serum IL-4 level. The Paris saponin can inhibit U14 cell growth and prolong survival time of mice; it is speculated that the Paris saponin may express its anti-tumor activity by improving the body's immune system.

  6. Supporting the development of an internationalization plan through benchmarking (case: medaffcon)

    OpenAIRE

    Tuompo, Tuuli

    2014-01-01

    In many cases, the small domestic market size in Finland forces organizations to start international operations in order to maintain growth. This thesis concentrates on find-ing success factors for the internationalization of Finnish based, service providing SMEs, operating in B2B markets. The data was collected from 3 participating organizations using benchmarking tech-niques. During the corporate visit data was collected using non-structured interviews, allowing the industry respected p...

  7. Franchising as strategy for internationalization of Family Firms: an exploratory study

    OpenAIRE

    Rosado-Serrano, Alexander; Universidad de Puerto Rico

    2017-01-01

    Family business is the most prevalent form of business thru out Latin America. Franchising has been a strategy used by many firms to expand domestically and internationally. Internationalization theories indicate that firms tend to expand to culturally close markets/countries. Family Business theories indicate that family firms have specific advantages in comparison with non-family firms. The purpose of this paper is to conduct a literature review about franchising family firms in Latin Ameri...

  8. Carmes Polytechnique, Housing in the Heart of Paris Energy renovation of a social housing estate in Paris

    Directory of Open Access Journals (Sweden)

    Christian Horn

    2017-12-01

    Full Text Available The architecture offices Atelier de la Seine and Rethink have been commissioned with the engineers Pouget Consultants by the social landlord Paris Habitat for the extensive renovation of a social housing estate in the historic centre of Paris. The estate has been built in 1930 and integrates a part of the former college of the Lombard build in the 17th century. It belongs to the social housing typology 'Habitations à Bon Marché (HBM' constructed between1894 and 1949. This typology is generally characterized by its integration in its urban context and an apparent brick facade. The renovation project includes a focus on the reduction of the energy consumption. An important subject, as of the total number of 4.6 millions of social housing in France more than 50 % have been build before 1975 (before the first thermal regulation and many are still considered energy-intensive.

  9. Moving Pictures: From Ethnographic to Autoethnographic Documentary in the Internationalization of the Geography Curriculum

    Science.gov (United States)

    Hay, Iain

    2017-01-01

    Documentary films have often taken a pivotal role in strategies to internationalize (geography) curricula and classrooms, being used as a method of bringing the world to the classroom. These documentaries overwhelmingly take ethnographic form. Problematically, the documentary gaze is characteristically that of an outside film crew and narrator…

  10. English as a Symbol of Internationalization in Higher Education: A Case Study of Vietnam

    Science.gov (United States)

    Duong, Van Anh; Chua, Catherine S. K.

    2016-01-01

    Vietnam universities have experienced remarkable changes brought about by their internationalization policies. The switch to English as a medium of instruction (EMI) for some academic programs was one of these critical changes. Literature has reported numerous issues related to EMI, including inadequate language proficiency of teaching staff. This…

  11. Discursive Inconvenience: The Dis/Appearing Rhetoric of LGBT Rights in Post-Secondary Internationalization Texts

    Science.gov (United States)

    Jubas, Kaela

    2015-01-01

    This paper outlines a preliminary document analysis of the intersection of two prominent discourses in the Western public academy: equity and internationalization. Particular dilemmas arise for people who self-identify as lesbian, gay, bisexual, or transgender (LGBT). These dilemmas, I propose, exemplify impacts of the neoliberal compulsion to let…

  12. The Evolution of a Practitioner; Transforming Praxis in Campus Internationalization and Beyond: An Autoethnography

    Science.gov (United States)

    Chervenock, Kristian

    2016-01-01

    Many universities and colleges across the country and around the globe are concentrating on becoming increasingly international. The extent to which they are internationalizing varies widely and depends greatly on strategic initiatives and priorities on the part of university administration, faculty, staff and students alike. Despite the many…

  13. Prophylaxis in congenital factor VII deficiency: indications, efficacy and safety. Results from the Seven Treatment Evaluation Registry (STER).

    Science.gov (United States)

    Napolitano, Mariasanta; Giansily-Blaizot, Muriel; Dolce, Alberto; Schved, Jean F; Auerswald, Guenter; Ingerslev, Jørgen; Bjerre, Jens; Altisent, Carmen; Charoenkwan, Pimlak; Michaels, Lisa; Chuansumrit, Ampaiwan; Di Minno, Giovanni; Caliskan, Umran; Mariani, Guglielmo

    2013-04-01

    Because of the very short half-life of factor VII, prophylaxis in factor VII deficiency is considered a difficult endeavor. The clinical efficacy and safety of prophylactic regimens, and indications for their use, were evaluated in factor VII-deficient patients in the Seven Treatment Evaluation Registry. Prophylaxis data (38 courses) were analyzed from 34 patients with severe factor VII deficiency (factor VII (24 courses), four received plasma-derived factor VII, and ten received fresh frozen plasma. Prophylactic schedules clustered into "frequent" courses (three times weekly, n=23) and "infrequent" courses (≤ 2 times weekly, n=15). Excluding courses for menorrhagia, "frequent" and "infrequent" courses produced 18/23 (78%) and 5/12 (41%) "excellent" outcomes, respectively; relative risk, 1.88; 95% confidence interval, 0.93-3.79; P=0.079. Long term prophylaxis lasted from 1 to >10 years. No thrombosis or new inhibitors occurred. In conclusion, a subset of patients with factor VII deficiency needed prophylaxis because of severe bleeding. Recombinant activated factor VII schedules based on "frequent" administrations (three times weekly) and a 90 μg/kg total weekly dose were effective. These data provide a rationale for long-term, safe prophylaxis in factor VII deficiency.

  14. Strategies for Industry Internationalization Brazilian Pulp and Paper the Perspective of Eclectic Paradigm: A Case Study of Pulp and Paper Company Suzano

    Directory of Open Access Journals (Sweden)

    Mayra Batista Bitencourt Fagundes

    2012-12-01

    Full Text Available This article aims to analyze the process of internationalization of the Brazilian pulp and paper. This analysis has an economic bias, basing on the model of internationalization of Eclectic Paradigm of Dunning (1980 in order to identify the internationalization strategies, as well as the key drivers that have enabled reach new markets. We adopted a qualitative methodology, developed through a case study in the company Suzano, a Brazilian company, a global leader in the pulp and paper industry, with a strong presence in the international market. The data were obtained from literature searches, statistics, press releases and official documents of the company. For the treatment of these was used to pattern matching techniques, which enabled contrast them with the theory selected. The results revealed that Suzano differentiated adopted guidelines for the marketing of paper and pulp. The paper is intended primarily for the domestic market, whereas most of the pulp produced is intended to international trade. The company went international for having, according to the Eclectic Paradigm, the advantages of ownership and internalization over their competitors. The strategies used consists in finding markets (market seeking, search efficiency (efficiency seeking and search for strategic assets (strategic asset seeking. We conclude that the theory is Eclectic Paradigm in an appropriate tool for analyzing the internationalization process of the pulp and paper industries.

  15. Paris: Beyond the Climate Dead End through Pledge and Review?

    Directory of Open Access Journals (Sweden)

    Robert O. Keohane

    2016-09-01

    Full Text Available The Paris Climate Agreement of December 2015 marks a decisive break from the unsuccessful Kyoto regime. Instead of targets and timetables, it established a Pledge and Review system, under which states will offer Nationally Determined Contributions (INDCs to reducing emissions that cause climate change. But this successful negotiation outcome was achieved at the price of vagueness of obligations and substantial discretion for governments. Many governments will be tempted to use the vagueness of the Paris Agreement, and the discretion that it permits, to limit the scope or intensity of their proposed actions. Whether Pledge and Review under the Paris Agreement will lead to effective action against climate change will therefore depend on the inclination both of OECD countries and newly industrializing countries to take costly actions, which for the OECD countries will include financial transfers to their poorer partners. Domestic politics will be crucial in determining the attitudes of both sets of countries to pay such costs. The actual impact of the Paris Agreement will depend on whether it can be used by domestic groups favoring climate action as a point of leverage in domestic politics—that is, in a “two-level game” simultaneously involving both international and domestic politics.

  16. Internationalization of higher education in Albania - Dilemmas and challenges: Albanian public and private universities in the new globalization era

    Directory of Open Access Journals (Sweden)

    Dr.Sc. Teuta Dobi

    2011-12-01

    Full Text Available Internationalization of higher education in Albania although an emerging necessity is still in very low figures not only as a connection between institutions but even as mobility between students. This paper sheds lights on internationalization at the regional and at the global level. It analyzes how the globalization and European integration processes are affecting public and private higher education institutions in Albania, their study programs and universities internal management structures. Firstly, it examines the overall changes in the Albanian HE sector since the beginning of 1990s. Then it explores the differences in internationalization between public and private universities and the ultimate changes on the Albanian labor market. My main thesis is that Albanian HE institutions increasingly need to put more efforts to internationalize their internal management structures and to put in practice international study programs. The paper analyzes more the advantages of the international study programs and the difficulties in a development country like Albania to implement them. The paper is based on the case study of the European University of Tirana and explores the difficulties of the faculties of this university to find financial support for international programs, research and travelling abroad, to develop courses with one international perspective, support for its students to study abroad, support to students from other countries and on other indicators such as grants, contracts and linkages in international areas. However the paper deals also with the academic requirements the issue of quality of universities in general. At the end the paper makes a prognosis of some strategies and gives some recommendations how to integrate the Albanian higher education institutions at a regional or global level.

  17. SMEs Going Global: A Comparison of the Internationalization Strategies of Publishers and Online Social Networks

    Directory of Open Access Journals (Sweden)

    Bettina Lis

    2012-01-01

    Full Text Available Up to now, most research has been conducted on the internationalization strategies of large media companies and groups. But tapping new foreign markets is also relevant to small- and medium-sized enterprises (SMEs of all media sectors. This paper therefore focuses on the internationalization strategies of different types of media SMEs. It aims at describing and comparing the motives for becoming an international player as well as the specific market selection, market entry, and market development strategies. Furthermore, it focuses on the main organizational implications. On the basis of a multiple-case design we compare two German regional newspaper publishers with two German special interest publishers and two online social business networks. Results show similarities and differences between these media sectors according to the nature of the media businesses. The cases also highlight the importance of international management skills also in the context of SMEs.

  18. Polyp morphology: an interobserver evaluation for the Paris classification among international experts.

    Science.gov (United States)

    van Doorn, Sascha C; Hazewinkel, Y; East, James E; van Leerdam, Monique E; Rastogi, Amit; Pellisé, Maria; Sanduleanu-Dascalescu, Silvia; Bastiaansen, Barbara A J; Fockens, Paul; Dekker, Evelien

    2015-01-01

    The Paris classification is an international classification system for describing polyp morphology. Thus far, the validity and reproducibility of this classification have not been assessed. We aimed to determine the interobserver agreement for the Paris classification among seven Western expert endoscopists. A total of 85 short endoscopic video clips depicting polyps were created and assessed by seven expert endoscopists according to the Paris classification. After a digital training module, the same 85 polyps were assessed again. We calculated the interobserver agreement with a Fleiss kappa and as the proportion of pairwise agreement. The interobserver agreement of the Paris classification among seven experts was moderate with a Fleiss kappa of 0.42 and a mean pairwise agreement of 67%. The proportion of lesions assessed as "flat" by the experts ranged between 13 and 40% (Pagreement did not change (kappa 0.38, pairwise agreement 60%). Our study is the first to validate the Paris classification for polyp morphology. We demonstrated only a moderate interobserver agreement among international Western experts for this classification system. Our data suggest that, in its current version, the use of this classification system in daily practice is questionable and it is unsuitable for comparative endoscopic research. We therefore suggest introduction of a simplification of the classification system.

  19. Correction of murine mucopolysaccharidosis VII by a human. beta. -glucuronidase transgene

    Energy Technology Data Exchange (ETDEWEB)

    Kyle, J.W.; Vogler, C.; Hoffmann, J.W.; Sly, W.S. (St. Louis Univ. School of Medicine, MO (USA)); Birkenmeier, E.H.; Gwynn, B. (Jackson Laboratory, Bar Harbor, ME (USA))

    1990-05-01

    The authors recently described a murine model for mucopolysaccharidosis VII in mice that have an inherited deficiency of {beta}-glucuronidase. Affected mice, of genotype gus{sup mps}/gus{sup mps}, present clinical manifestations similar to those of humans with mucopolysaccharidosis VII (Sly syndrome) and are shown here to have secondary elevations of other lysosomal enzymes. The mucopolysaccharidosis VII phenotype in both species includes dwarfism, skeletal deformities, and premature death. Lysosome storage is visualized within enlarged vesicles and correlates biochemically with accumulation of undegraded and partially degraded glycosaminoglycans. In this report they describe the consequences of introducing the human {beta}-glucuronidase gene, GUSB, into gus{sup mps}/gus{sup mps} mice that produce virtually no murine {beta}-glucuronidase. Transgenic mice homozygous for the mucopolysaccharidosis VII mutation expressed high levels of human {beta}-glucuronidase activity in all tissues examined and were phenotypically normal. Biochemically, both the intralysosomal storage of glycosaminoglycans and the secondary elevation of other acid hydrolases were corrected. These findings demonstrate that the GUSB transgene is expressed in gus{sup mps}/gus{sup mps} mice and that human {beta}-glucuronidase corrects the murine mucopolysaccharidosis storage disease.

  20. [Development strategy of Paris based on combination of domestic patent and current resource application and development].

    Science.gov (United States)

    Zhao, Fei-Ya; Tao, Ai-En; Xia, Cong-Long

    2018-01-01

    Paris is a commonly used traditional Chinese medicine (TCM), and has antitumor, antibacterial, sedative, analgesic and hemostatic effects. It has been used as an ingredient of 81 Chinese patent medicines, with a wide application and large market demand. Based on the data retrieved from state Intellectual Property Office patent database, a comprehensive analysis was made on Paris patents, so as to explore the current features of Paris patents in the aspects of domestic patent output, development trend, technology field distribution, time dimension, technology growth rate and patent applicant, and reveal the development trend of China's Paris industry. In addition, based on the current Paris resource application and development, a sustainable, multi-channel and multi-level industrial development approach was built. According to the results, studies of Paris in China are at the rapid development period, with a good development trend. However, because wild Paris resources tend to be exhausted, the studies for artificial cultivation technology should be strengthened to promote the industrial development. Copyright© by the Chinese Pharmaceutical Association.

  1. Plasma factor VII-activating protease is increased by oral contraceptives and induces factor VII activation in-vivo

    DEFF Research Database (Denmark)

    Sidelmann, Johannes Jakobsen; Skouby, Sven O.; Kluft, Cornelis

    2011-01-01

    progestins. FSAP genotypes, FSAP and factor VII (FVII) plasma measures were assessed at baseline and after 6 cycles of OC. The 1601GA genotype was present in 49 (8.3%) of the women and was associated with significantly reduced levels of FSAP (P≤0.001). OC use increased FSAP antigen by 25% and FSAP activity......Oral contraceptive (OC) use influences the hemostatic system significantly and is a risk factor for development of cardiovascular disease. Factor VII-activating protease (FSAP) has potential effects on hemostasis. The 1601GA genotype of the 1601G/A polymorphism in the FSAP gene expresses a FSAP...... by 59% (P0.05). The relative increase in FSAP activity was significantly higher in women carrying the 1601GG genotype (63%) than in women carrying 1601GA genotype (50%) (P=0.01) and was associated with an increased activation of FVII. In conclusion: OC use increases the plasma measures of FSAP...

  2. The Internationalization Process of the E-marketplace Scanmarket A/S

    DEFF Research Database (Denmark)

    Rask, Morten

    The case describes the early internationalization process and the considerations about future international expansion of a successful e-marketplace where customers (doing reverse auctions) are the focus. Scanmarket was trying to find identify the most suitable entry modes; i.e. types of entry mod...... facing managers of dot.com firms. The case can be used in different types of teaching situations: (1) classroom discussions; (2) as an illustrative case applied to theoretical issues used in lectures; and (3) finally as the basis for examinations....

  3. Understanding the Paris agreement: analysing the reporting requirements under the enhanced transparency framework

    DEFF Research Database (Denmark)

    Desgain, Denis DR; Sharma, Sudhir

    At the Paris climate conference (COP-21) in December 2015, the Conference of the Parties decided to adopt the Paris Agreement under the United Nations Framework Convention on Climate Change. This was the first time that 195 Parties had agreed on a universal, legally binding climate instrument......th October 2016, 74 Par¬ties had ratified the Agreement, accounting for 58.82% of global GHG emissions.1 The Paris Agreement will thus enter into force on 4th November 2016....

  4. 40 CFR Appendix Vii to Part 268 - LDR Effective Dates of Surface Disposed Prohibited Hazardous Wastes

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 26 2010-07-01 2010-07-01 false LDR Effective Dates of Surface Disposed Prohibited Hazardous Wastes VII Appendix VII to Part 268 Protection of Environment ENVIRONMENTAL... VII to Part 268—LDR Effective Dates of Surface Disposed Prohibited Hazardous Wastes Table 1—Effective...

  5. The internationalization of the technological activities in the energy industries; L'internationalisation des activites technologiques dans les industries energetiques

    Energy Technology Data Exchange (ETDEWEB)

    Bourgeois, B. [Institut d' Economie et de Politique de l' Energie - IEPE-CNRS/ Universite Pierre Mendes-France, 38 - Grenoble (France); Jacquier-Roux, V. [Institut de Recherche Economique sur la Production et le Developpement -IREPD, 38 - Grenoble (France)

    2001-06-01

    This analysis of the technological internationalization factors is defined in five chapters. The first chapter deals with the evolutionist representation of the internationalization process of the technological activities of the firms. The chapter two is an historical synthesis from 1985 to 2000, of the industrial dynamics and of the technological strategies of the petroleum and electric power industries. The chapter three details the empirical method used to verify the hypothesis. Chapter four exposes the data analysis results of the patents of the sampled firms. The last chapter is devoted to the results interpretation. (A.L.B.)

  6. Management trends: Internationalization of non-profit organizations

    Directory of Open Access Journals (Sweden)

    Inić Branimir P.

    2015-01-01

    Full Text Available Non-profit organizations are increasingly gaining importance in the modern economy with their development and their numbers increasing day by day. It is very important to note that non-profit organizations are often subject to various benefits that the for-profit companies are not. Thus, for example, preferential tax status of non-profit organizations is manifested primarily in the form of exemption from corporate income tax. In addition, private non-profit organizations enjoy various other state, local and federal taxes exemptions. Under certain conditions, these organizations are exempt from taxes on donations and membership fees. A feature that differentiates various non-profit organizations and profit-oriented companies is their source of income. Profit oriented companies depend on their income, obtained from sales of their goods or services to customers, who usually cover the price and cost of goods and services plus the profit. In contrast, nonprofit organizations are very dependent on membership fees, tax exemptions, members donations or depend on funds of the sponsoring agency which covers most of their costs, for example a federal government agency. Those non-profit organizations that have substantial operating costs beyond national borders and do not identify themselves as purely domestic in their mandate are International non-profit organizations. Most non-profit organizations remain in their national boundaries, on the territory of the country in which they were created, but a large number of non-profit organizations rapidly internationalize, and some larger non-profits have grown into important global actors. The paper includes the following sections: (1 introduction, (2 why is the 'non-profit' important, (3 the internationalization of non-profit organizations, (4 sources of income of non-profit organizations (4.1. causality of impact and of strategic decisions in cases pertaining to universities, (5 the limits of strategic

  7. Internationalization as Mergers and Acquisitions: Senior International Officers' Entrepreneurial Strategies and Activities in Public Universities

    Science.gov (United States)

    Deschamps, Eric; Lee, Jenny J.

    2015-01-01

    This study investigated the various emerging forms of internationalization and how senior international affairs officers describe their motivations and rationales for implementing these activities. Based on interviews with senior international officers at 30 international offices in U.S. public universities, this study identified and classified…

  8. GHG monitoring over Paris megacity and Orléans forest

    Science.gov (United States)

    Te, Y. V.; Jeseck, P.; Zanon, T.; Boursier, C.; Janssen, C.; Deutscher, N. M.; Warneke, T.; Notholt, J.; Lac, C.; Dieudonné, E.; Lopez, M.; Schmidt, M.; Xueref-remy, I. C.

    2012-12-01

    In a growing world with more than 7 billion inhabitants and big emerging countries such as China, Brazil and India, emissions of anthropogenic pollutants and greenhouse gases (GHGs) are increasing continuously. Their monitoring and control in megacities have become a major challenge for scientists and public health authorities in environmental research area. The ground-based Fourier transform spectrometer (QualAir FTS[a], model IFS 125HR) of the QualAir platform located in downtown Paris at University Pierre et Marie Curie (UPMC), is a scientific research instrument dedicated to the survey of greenhouse gases (GHGs) and urban air quality. Equipped with a sun-tracker, the remote sensing QualAir FTS relies on solar infrared absorption for monitoring trace gas concentrations and their variability in the Ile-de-France region[b]. Concentrations of atmospheric GHGs, especially CO2, CH4 and N2O, are retrieved by the radiative transfer model PROFFIT[c]. Because Paris is the third largest European megacity, the QualAir FTS can provide new and complementary measurements as compared to existing ground-based FTS network stations (NDACC and TCCON) located in unpolluted environments, such as the TCCON-Orléans station[d] situated in the forest of Orléans (100 km south of Paris). In the effort to integrate QualAir FTS into the TCCON network, simultaneous FTS measurements of GHGs at Paris and Orléans have been performed. We will emphasize on comparisons of CO2 from these two sites. Our comparison will be completed by high-resolved direct CO2 modeling outputs from the Meso-NH model, and ground in situ measurements at different sites (Orléans/Trainou, Paris/Jussieu, Paris/Eiffel Tower). Parts of the data were acquired in the framework of the French CO2-MEGAPARIS project[e, f], whose main goal is to quantify CO2 emissions from the Paris area. The present data intercomparison will help to reduce uncertainties in carbon cycle models and to better characterize regional GHG fluxes

  9. Strategies and logics of internationalization

    Directory of Open Access Journals (Sweden)

    Mahjouba Ben Salem

    2013-07-01

    Full Text Available The race between firms to acquire capacities worldwide has evolved in a chronological order which centered at first around products, then around position to move later on to skills and to focus currently on networks. Similarly, when observing the evolution of the different international development strategies, it was found out that they have started by the exportation and the setting up of production subsidiaries to move more recently to such strategies as mergers & acquisitions and international alliances. The present paper investigates the relationship between the internationalization strategies and logics and comes to the conclusion that, a particular logic is behind every choice made. Indeed, the present work was conducted within the Tunisian food enterprises and helped confirm this hypothesis as it was found out that the position logic is behind the choice of exportation and the creation of production subsidiaries while the choice of partnership is based on the logic of skills. The option for merger, on the other hand, is motivated by the networks logic.

  10. Internationalized and research-oriented photonics education: Abbe School of Photonics

    Science.gov (United States)

    Helgert, Christian; Nolte, Stefan; Pertsch, Thomas

    2015-10-01

    The Abbe School of Photonics (ASP) provides and coordinates the optics and photonics education of graduate and doctoral students at the Friedrich Schiller University in Jena, Germany. The internationalized Master's degree program is the key activity in training students in the optical sciences. The program is designed to provide them with the skills necessary to fill challenging positions in industry and academia. Here, an essential factor is ASP's close collaboration with more than 20 German photonics companies. To sustain these partners' future economic development, the availability of highly qualified employees is constantly required. Accordingly, these industrial partners, the European Union, the local state and the federal German government are strongly involved in the sustainable development of ASP's curriculum by both conceptual and financial engagements. The main goal is to promote the students' academic careers and job experience in the photonics industry as well as in academia. To open up the program to students from all over the world, all ASP lectures and courses are taught in English. Since 2009, more than 250 graduate students from more than 40 different countries have been enrolled at the School. Almost 90% of them of non-German nationality, fulfilling the essential ASP philosophy to locally establish an international education program. ASP's qualification strategy is fully research-oriented and based on the principles of academic freedom, competitive research conditions and internationalization at all levels. The education program is complemented by a structured doctoral student support and a prestigious guest professorship program.

  11. Gene disruption reveals a dispensable role for plasmepsin VII in the Plasmodium berghei life cycle.

    Science.gov (United States)

    Mastan, Babu S; Kumari, Anchala; Gupta, Dinesh; Mishra, Satish; Kumar, Kota Arun

    2014-06-01

    Plasmepsins (PM), aspartic proteases of Plasmodium, comprises a family of ten proteins that perform critical functions in Plasmodium life cycle. Except VII and VIII, functions of the remaining plasmepsin members have been well characterized. Here, we have generated a mutant parasite lacking PM VII in Plasmodium berghei using reverse genetics approach. Systematic comparison of growth kinetics and infection in both mosquito and vertebrate host revealed that PM VII depleted mutants exhibited no defects in development and progressed normally throughout the parasite life cycle. These studies suggest a dispensable role for PM VII in Plasmodium berghei life cycle. Copyright © 2014 Elsevier B.V. All rights reserved.

  12. Paris Conference (Further report)

    International Nuclear Information System (INIS)

    Anon.

    1982-01-01

    From 26-31 July, the international particle physics community met for its traditional biennial 'Rochester' jamboree, held this time in Paris. While there were no major physics surprises, there was still plenty of interest for all and the ground that was covered amply demonstrated the progress which has been made since the previous round of international meetings. The emphasis is very much on improving the already considerable level of agreement between different experiments and between experimental results and theoretical predictions

  13. Um olhar de descoberta na Paris da Belle Époque

    Directory of Open Access Journals (Sweden)

    João Carrascoza

    2008-09-01

    Full Text Available Ao estilo dos textos de Baudelaire sobre os flâneurs que caminhavam na cidade de Paris, descobrindo os símbolos da modernidade, este artigo narra a chegada de um estrangeiro à capital francesa no início do século XX e seu passeio pela cidade. Ao longo de um dia, ele tomará contato com as obras de importantes artistas como Toulouse-Lautrec, Murcha e Chéret, que desenharam cartazes para shows, embalagens de produtos, folhetos promocionais, entre outras manifestações artísticas exploradas pelo então nascente espírito moderno. À semelhança do romance de Umberto Eco, A misteriosa chama da rainha Loana, que reproduz imagens da cultura pop e erudita em meio à sua narrativa, o texto segue o formato de ensaio ilustrado, fundindo a ficção com os aspectos reais da Paris na efervescência da Belle Époque. A estrutura, portanto, rompe com os gêneros tradicionais dos artigos acadêmicos, apresentando conteúdo reflexivo por meios dos personagens e da trama engendrada. Palavras-chave: Paris; Belle Époque; modernidade; imagens; publicidade. ABSTRACT In the style of Baudelaire’s texts on the flâneurs who used to walk in the city of Paris, finding the symbols of modernity, this article narrates the ar- rival of a foreigner in the early 20th century in Paris, and his tour around the French capital. In the course of one day, he will be in contact with the works of important artists, such as Toulouse-Lautrec, Murcha and Chéret, who drew posters for shows, products’ packages, advertising leaflets, among other artistic manifestations, explored by the then rising modern spirit. Similar to Umberto Eco’s novel The mysterious flame of Queen Loana, which reproduces images of both pop and erudite culture in its narrative, the text follows the illustrated essay format, merging fiction and the real aspects of Paris’ effervescent Belle Époque. The structure, therefore, breaks free from the traditional genres of academic articles, presenting the

  14. Examining internationalization of the professional services firm

    DEFF Research Database (Denmark)

    Skaates, Maria Anne

    2003-01-01

    of architectural services to Germany in the 1990s, the types of knowledge the case firms needed to acquire and use to obtain German architectural projects, and the project acquisition process, including especially the role that previous project work plays in project acquisitions abroad. The results of the research......) and Bourdieu's social and cultural capital theory could be combined to explain the dynamics of the project acquisition process, including the role of previous project work. The study resulted in seven general hypothetical propositions and four managerially-relevant general models which should be externally...... sociologist Pierre Bourdieu's social and cultural capital framework and various contributions from reference theory and the boundary spanner and knowledge management literatures. The study's research questions focus on understanding relations between the actors involved in the Danish internationalization...

  15. A thyrotoxicosis outbreak due to dietary pills in Paris

    Directory of Open Access Journals (Sweden)

    Vincent Ioos

    2008-10-01

    Full Text Available Vincent Ioos1, Vincent Das1, Eric Maury1,2, Jean-Luc Baudel1, Jérôme Guéchot3, Bertrand Guidet1,2, Georges Offenstadt1,21Réanimation Médicale; 2Université Pierre et Marie Curie-Paris 6, INSERM, UMR-S 707; 3Unité d’Hormonologie, APHP, Hôpital Saint Antoine, F-75012, Paris, FranceAbstract: Three women were consecutively admitted to our medical intensive care unit for thyrotoxicosis after the ingestion of dietary pills accidentally containing high levels of thyroxin. These cases were observed during an outbreak in the Paris area. Despite similar blood levels of thyroid hormones, their clinical presentation and outcome were very different. One patient developed febrile confusion and died from malignant hyperthermia. The second one had progressive confusion requiring mechanical plasma exchange therapy and had a favorable outcome. The third one had very moderate symptoms. These exceptional observations raise several issues concerning diagnosis, physiopathology and treatment of thyrotoxicosis factitia.Keywords: thyrotoxicosis, dietary pills, thyroxin

  16. Faculty Internationalization: Experiences, Attitudes, and Involvement of Faculty at Public Universities in South Dakota

    Science.gov (United States)

    Doyle, Kevin

    2013-01-01

    Internationalization in higher education is an issue of growing importance as the forces of globalism continue to push both social and economic connections from local to global. While this topic is becoming increasingly vital to the health and influence of educational institutions, many, including those within South Dakota, are unaware of the…

  17. ABB’s Internationalization in the Emerging Chinese Market : Entry Mode and Market Development Progress

    OpenAIRE

    Phan Van, Thang; Xin, Zhang

    2008-01-01

    The aim of the thesis is to describe the entry mode choice and market development progress of the successful MNC ABB in the specific emerging market China. The authors also want to use theories in the master course of International Business and Entrepreneurship to explain the internationalization of one specific company ABB

  18. China's response to climate change issues after Paris Climate Change Conference

    Directory of Open Access Journals (Sweden)

    Yun Gao

    2016-12-01

    Full Text Available The Paris Climate Change Conference was successfully concluded with the Paris Agreement, which is a milestone for the world in collectively combating climate change. By participating in IPCC assessments and conducting national climate change assessments, China has been increasing its understanding of the issue. For the first time, China's top leader attended the Conference of the Parties, which indicates the acknowledgement of the rationality and necessity of climate change response by China at different levels. Moreover, this participation reflects China's commitment to including climate change in its ecology improvement program and pursuing a low-carbon society and economy. In order to ensure the success of the Paris Conference, China has contributed significantly. China's constructive participation in global governance shows that China is a responsible power. These principles such as the creation of a future of win–win cooperation with each country contributing to the best of its ability; a future of the rule of law, fairness, and justice; and a future of inclusiveness, mutual learning, and common development will serve as China's guidelines in its efforts to facilitate the implementation of the Paris Agreement and participate in the design of international systems.

  19. China's response to climate change issues after Paris Climate Change Conference

    Institute of Scientific and Technical Information of China (English)

    GAO Yun

    2016-01-01

    The Paris Climate Change Conference was successfully concluded with the Paris Agreement, which is a milestone for the world in collectively combating climate change. By participating in IPCC assessments and conducting national climate change assessments, China has been increasing its understanding of the issue. For the first time, China's top leader attended the Conference of the Parties, which indicates the acknowledgement of the rationality and necessity of climate change response by China at different levels. Moreover, this participation reflects China's commitment to including climate change in its ecology improvement program and pursuing a low-carbon society and economy. In order to ensure the success of the Paris Conference, China has contributed significantly. China's constructive participation in global governance shows that China is a responsible power. These principles such as the creation of a future of winewin cooperation with each country contributing to the best of its ability;a future of the rule of law, fairness, and justice;and a future of inclusiveness, mutual learning, and common development will serve as China's guidelines in its efforts to facilitate the implementation of the Paris Agreement and participate in the design of international systems.

  20. Methodology for Assessing the Degree of Internationalization of Business Academic Study Programmes

    OpenAIRE

    Dan-Cristian Dabija; Cătălin Postelnicu; Nicolae Al. Pop

    2014-01-01

    The purpose of this paper is to develop a methodology for assessing the degree of internationalization of undergraduate, Master’s and doctoral business programmes with the aid of complex indicators designed to capture the vast array of characteristics displayed by these programmes and contribute to their promotion in the international academic competition. The methodology should include both general indicators applicable to any study programme and some indicators that are specifically develop...

  1. Activation of factor VII bound to tissue factor: A key early step in the tissue factor pathway of blood coagulation

    International Nuclear Information System (INIS)

    Rao, L.V.M.; Rapaport, S.I.

    1988-01-01

    Whether the factor VII/tissue factor complex that forms in tissue factor-dependent blood coagulation must be activated to factor VIIa/tissue factor before it can activate its substrates, factor X and IX, has been a difficult question to answer because the substrates, once activated, back-activate factor VII. The earlier studies suggested that human factor VII/tissue factor cannot activate factor IX. Studies have now been extended to the activation of factor X. Reaction mixtures were made with purified factor VII, X, and tissue factor; in some experiments antithrombin III and heparin were added to prevent back-activation of factor VII. Factor X was activated at similar rates in reaction mixtures containing either VII or factor VIIa after an initial 30-sec lag with factor VII. In reaction mixtures with factor VII a linear activation of factor X was established several minutes before cleavage of 125 I-labeled factor VII to the two-chain activated molecule was demonstrable on gel profiles. These data suggest that factor VII/tissue factor cannot activate measurable amounts of factor X over several minutes. Overall, the results support the hypothesis that a rapid preferential activation of factor VII bound to tissue factor by trace amounts of factor Xa is a key early step in tissue factor-dependent blood coagulation

  2. Synthesis, purification, and characterization of an Arg152 → Glu site-directed mutant of recombinant human blood clotting factor VII

    International Nuclear Information System (INIS)

    Wildgoose, P.; Kisiel, W.; Berkner, K.L.

    1990-01-01

    Coagulation factor VII circulates in blood as a single-chain zymogen of a serine protease and is converted to its activated two-chain form, factor VIIa, by cleavage of an internal peptide bond located at Arg 152 -Ile 153 . Previous studies using serine protease active-site inhibitors suggest that zymogen factor VII may possess sufficient proteolytic activity to initiate the extrinsic pathway of blood coagulation. In order to assess the putative intrinsic proteolytic activity of single-chain factor VII, the authors have constructed a site-specific mutant of recombinant human factor VII in which arginine-152 has been replaced with a glutamic acid residue. Mutant factor VII was purified in a single step from culture supernatants of baby hamster kidney cells transfected with a plasmid containing the sequence for Arg 152 → Glu factor VII using a calcium-dependent, murine anti-factor VII monoclonal antibody column. The clotting activity of mutant factor VII was completely inhibited following incubation with dansyl-Glu-Gly-Arg chloromethyl ketone, suggesting that the apparent clotting activity of mutant factor VII was due to a contaminating serine protease. Immunoblots of mutant factor VII with human factor IXa revealed no cleavage, whereas incubation of mutant factor VII with human factor Xa resulted in cleavage of mutant factor VII and the formation of a lower molecular weight degradation product migrating at M r ∼40 000. The results are consistent with the proposal that zymogen factor VII possesses no intrinsic proteolytic activity toward factor X or factor IX

  3. Internationalization at Harvard

    Directory of Open Access Journals (Sweden)

    Ned Strong

    2013-06-01

    Full Text Available The aim of this essay is to describe internationalization at Harvard University. Founded by European colonists in 17th century New England, Harvard has historic international roots. By the mid 1900’s it had become an international powerhouse attracting top students, academics and scientists from around the world. Yet, the University is international almost by default as it has reacted to world affairs. Looking toward the future, President Drew Faust has outlined a strategy to become “intentionally global”. One model, begun ten years ago, serves as an example for the future. In 2002 the University established its first overseas office designed to represent the entire institution. The theory was that a modest local infrastructure would encourage students and faculty to expand international collaborations and make a difference in the region benefiting from this presence. The results have been highly successful. The Regional Office in Santiago Chile, representing Argentina, Bolivia, Chile, Peru, and Uruguay, has catalyzed engagement of over 3000 faculty and students in the last ten years. Over 50 significant collaborative research programs have benefitted thousands of preschool children, pioneered new approaches to disaster relief, improved health care, revolutionized public housing, and led to scientific breakthroughs. This model of a small physical footprint exerting large academic influence will be one of the central strategies as Harvard looks toward the future. DOI: 10.18870/hlrc.v3i2.117

  4. Internationalization as De-Westernization of the Curriculum: The Case of Journalism at an Australian University

    Science.gov (United States)

    Breit, Rhonda; Obijiofor, Levi; Fitzgerald, Richard

    2013-01-01

    Internationalization of the curriculum points to the interdependent and interconnected (globalized) world in which higher education operates. However, while international awareness is crucial to the study of journalism, in practice this often means an Anglo-American curriculum based around Western principles of journalism education and training…

  5. Design and Intervention of an Educational-Leadership Program: Student Voice and Agency, Expectations and Internationalization

    Science.gov (United States)

    du Plessis, Anna Elizabeth

    2017-01-01

    This paper explores the lived experiences of a diverse student cohort enrolled in a master's degree educational-leadership program. The program's global focus was on the quality of teacher education, prospective teachers' workplace preparedness and leaders in the workforce in higher education. Internationalization, real-life experiences and…

  6. Evaluated Nuclear Data Covariances: The Journey From ENDF/B-VII.0 to ENDF/B-VII.1

    International Nuclear Information System (INIS)

    Smith, Donald L.

    2011-01-01

    Recent interest from data users on applications that utilize the uncertainties of evaluated nuclear reaction data has stimulated the data evaluation community to focus on producing covariance data to a far greater extent than ever before. Although some uncertainty information has been available in the ENDF/B libraries since the 1970's, this content has been fairly limited in scope, the quality quite variable, and the use of covariance data confined to only a few application areas. Today, covariance data are more widely and extensively utilized than ever before in neutron dosimetry, in advanced fission reactor design studies, in nuclear criticality safety assessments, in national security applications, and even in certain fusion energy applications. The main problem that now faces the ENDF/B evaluator community is that of providing covariances that are adequate both in quantity and quality to meet the requirements of contemporary nuclear data users in a timely manner. In broad terms, the approach pursued during the past several years has been to purge any legacy covariance information contained in ENDF/B-VI.8 that was judged to be subpar, to include in ENDF/B-VII.0 (released in 2006) only those covariance data deemed then to be of reasonable quality for contemporary applications, and to subsequently devote as much effort as the available time and resources allowed to producing additional covariance data of suitable scope and quality for inclusion in ENDF/B-VII.1. Considerable attention has also been devoted during the five years since the release of ENDF/B-VII.0 to examining and improving the methods used to produce covariance data from thermal energies up to the highest energies addressed in the ENDF/B library, to processing these data in a robust fashion so that they can be utilized readily in contemporary nuclear applications, and to developing convenient covariance data visualization capabilities. Other papers included in this issue discuss in considerable

  7. Corporate governance and internationalization of capital of brazilian companies of the sectors construction and transports

    Directory of Open Access Journals (Sweden)

    Anna Beatriz Grangeiro Ribeiro Maia

    2013-08-01

    Full Text Available The study aims at analyzing comparatively the representativeness of foreign capital in the capital of Brazilian companies of the sectors construction and transports, considering their segments on the BM&FBovespa. The internationalization of the 66 companies in the sample was measured by the percentage of the company's share capital held by foreign investors, and governance by the company's participation on the “Differentiated Level of Corporate Governance” (DLCG segments of BM&FBovespa. Using a descriptive and a quantitative study, the results of applying the Mann-Whitney test for the percentage of foreign capital in the capital of DLCG firms and of companies listed on the traditional market indicate that there is a difference statistically significant between the two groups of firms, confirming the hypothesis of this research. The conclusion is that governance is a sign of the internationalization of capital companies, confirming the efficiency of the administration based on the theory of transaction costs.

  8. Molecular, Cellular and Pharmaceutical Aspects of Biomaterials in Dentistry and Oral and Maxillofacial Surgery. An Internationalization of Higher Education and Research Perspective.

    Science.gov (United States)

    Wisniewska, Lidia M; Dohan Ehrenfest, David M; Galindo-Moreno, Pablo; Segovia, Jesus D; Inchingolo, Francesco; Wang, Hom-Lay; Fernandes-Cruz, Manuel

    2017-01-01

    In dentistry and oral and maxillofacial surgery, the development of implantable biomaterials and the understanding of their molecular, cellular and pharmaceutical aspects are currently major fields of research and education, with a considerable impact on the daily clinical practice and the evolution of therapeutic strategies. In the era of globalized economy of knowledge and science, this scientific domain needs the development of global cooperation and a paradigm evolution in the organizational culture of the dental sciences and related dental industry. Despite political pressure and theoretical efforts, the internationalization of higher education and research today in dentistry and biomaterials remains in general quite superficial and mostly dependent on the efforts of a few leaders of internationalization working through their personal networks, as it was assessed through the FAST scores (Fast Assessment Screening Test) calculated in various dental schools and groups worldwide through the ISAIAS program (Intercultural Sensitivity Academic Index &Advanced Standards). Cooperation in a multipolar multicultural community requires the development of strong intercultural competences, and this process remains limited in most institutions. These limits of international scientific cooperation can be observed through different markers, particularly the difficult and limited production of ISO standards (International Organization for Standardization) and the relatively low SCIENTI scores (Scientific Cooperation Internationalization Effort &Network Test &Index) of the specialized dental literature, particularly in comparison to the most significant medical literature. However, as an analytical tool to assess the scientific international cooperation effort between fields and periods, the SCIENTI screening system also highlighted a significant increase of the internationalization effort in the last years in the best dental biomaterials publications. Finally, an

  9. ClimasCOPe: Exploring the challenges behind the Paris Agreement - COP21

    International Nuclear Information System (INIS)

    Leguet, Benoit; Alberola, Emilie; Afriat, Marion; Vaidyula, Manasvini; Morel, Romain; Cochran, Ian; Deheza, Mariana; Shishlov, Igor; Leseur, Alexia; Depoues, Vivian; Bordier, Cecile; Bultheel, Clement; Bellassen, Valentin

    2015-04-01

    In the framework of the 21. Conference of the Parties (COP21) to the United Nations Framework Convention on Climate Change (UNFCCC), held in Paris from November 30 to December 11 2015, I4CE - Institute for Climate Economics, in partnership with ADEME, the French Environment and Energy Management Agency, attempts to shed some light on the challenges surrounding this Paris Climate Conference 2015. They explore what can be expected from the post-2020 climate agreement in Paris. They also discuss some keys success indicators of such an agreement. Over the course of six issues, ClimasCOPe provides analysis related to carbon pricing, climate finance, greenhouse gas (GHG) emissions' accounting, the role of sub-national actors, adaptation to climate change and the compatibility of government commitments with the scenario where in global mean temperatures would rise by no more than 2 deg. C. Issue 1 - Carbon pricing: a necessary tool on the agenda of solutions for climate funding (Putting a Price on Carbon, First submissions of intended Nationally Determined Contributions for Paris Agreement, 5 carbon pricing initiatives); Issue 2 - Financing the low-carbon transition: the need for coherence between regulations and ambition (Finance will be the cornerstone of the Paris accord, News, 5 initiatives for Climate Finance); Issue 3 - Three keys to effective GHG emissions monitoring for a broader climate agreement (MRV: how to hit the bull's eye when there is no silver bullet? First Climate Week and the Bonn negotiations, 3 MRV initiatives); Issue 4 - Non-state actors: pushing the climate action agenda forward (The role of cities and regions and their knock-on effects, G7 announcements and the process of adopting the SDGs, 4 non-state actor initiatives); Issue 5 - COP 21: a new approach and the launch of a process to address climate change adaptation (Adapting to climate change: taking ownership of the issues and removing barriers to implementation, First COP 21 draft

  10. Synthesis and characterization of 18F-labeled active site inhibited factor VII (ASIS)

    DEFF Research Database (Denmark)

    Erlandsson, Maria; Nielsen, Carsten Haagen; Jeppesen, Troels Elmer

    2015-01-01

    Activated factor VII blocked in the active site with Phe-Phe-Arg-chloromethyl ketone (active site inhibited factor VII (ASIS)) is a 50-kDa protein that binds with high affinity to its receptor, tissue factor (TF). TF is a transmembrane glycoprotein that plays an important role in, for example......, thrombosis, metastasis, tumor growth, and tumor angiogenesis. The aim of this study was to develop an 18F-labeled ASIS derivative to assess TF expression in tumors. Active site inhibited factor VII was labeled using N-succinimidyl-4-[18F]fluorobenzoate, and the [18F]ASIS was purified on a PD-10 desalting...... column. The radiochemical yield was 25 ± 6%, the radiochemical purity was >97%, and the pseudospecific radioactivity was 35 ± 9 GBq/µmol. The binding efficacy was evaluated in pull-down experiments, which monitored the binding of unlabeled ASIS and [18F]ASIS to TF and to a specific anti-factor VII...

  11. FY2000 survey report research and development internationalization in industrial sector among APEC economies

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    A survey is conducted and a database is constructed on internationalization of research and development activities in the industrial sectors of APEC (Asia-Pacific Economic Cooperation Conference) countries, namely, on research and development support systems, research and development appropriations, research and development personnel, research VISA granting procedures and control over foreign funds, trends of research and development among private sector businesses, main research and development organizations, evaluation by private sector businesses of the research and development environments of their countries, and the like. Incorporated into the database are Australia, Brunei, Canada, Chile, China, Hong Kong, Indonesia, Japan, Korea, Malaysia, Mexico, New Zealand, Papua New Guinea, Peru, Philippines, Russia, Singapore, Chinese Taipei, Thailand, United States, and Vietnam. The database, compiled for Internet web pages, CD-ROMs, and publications, covers the industrial technology related policies of all the countries and helps understand the research and development systems, and enables access to main research organizations. The database comprises a general section dealing with the background, system constitution, and internationalization trend and a countries section collecting information on the respective countries. (NEDO)

  12. Topical application of recombinant activated factor VII during cesarean delivery for placenta previa.

    Science.gov (United States)

    Schjoldager, Birgit T B G; Mikkelsen, Emmeli; Lykke, Malene R; Præst, Jørgen; Hvas, Anne-Mette; Heslet, Lars; Secher, Niels J; Salvig, Jannie D; Uldbjerg, Niels

    2017-06-01

    During cesarean delivery in patients with placenta previa, hemorrhaging after removal of the placenta is often challenging. In this condition, the extraordinarily high concentration of tissue factor at the placenta site may constitute a principle of treatment as it activates coagulation very effectively. The presumption, however, is that tissue factor is bound to activated factor VII. We hypothesized that topical application of recombinant activated factor VII at the placenta site reduces bleeding without affecting intravascular coagulation. We included 5 cases with planned cesarean delivery for placenta previa. After removal of the placenta, the surgeon applied a swab soaked in recombinant activated factor VII containing saline (1 mg in 246 mL) to the placenta site for 2 minutes; this treatment was repeated once if the bleeding did not decrease sufficiently. We documented the treatment on video recordings and measured blood loss. Furthermore, we determined hemoglobin concentration, platelet count, international normalized ratio, activated partial thrombin time, fibrinogen (functional), factor VII:clot, and thrombin generation in peripheral blood prior to and 15 minutes after removal of the placenta. We also tested these blood coagulation variables in 5 women with cesarean delivery planned for other reasons. Mann-Whitney test was used for unpaired data. In all 5 cases, the uterotomy was closed under practically dry conditions and the median blood loss was 490 (range 300-800) mL. There were no adverse effects of recombinant activated factor VII and we did not measure factor VII to enter the circulation. Neither did we observe changes in thrombin generation, fibrinogen, activated partial thrombin time, international normalized ratio, and platelet count in the peripheral circulation (all P values >.20). This study indicates that in patients with placenta previa, topical recombinant activated factor VII may diminish bleeding from the placenta site without initiation

  13. TEH võrgustik - viis aastat Eestis / Marika Kusnets

    Index Scriptorium Estoniae

    Kusnets, Marika

    2005-01-01

    Eestis on tervist edendavate haiglate (TEH) võrgustik tegutsenud juba viis aastat, sellega on liitunud 22 haiglat. Tänavust konverentsi peeti teemal "Tervise edendamine ja kvaliteedi tagamine haiglas: standardid ja praktika"

  14. INTERNATIONALIZATION OF ECONOMIC ACTIVITIES AND GOVERNMENT’S INVOLVEMENT IN THE MARKET ECONOMY

    Directory of Open Access Journals (Sweden)

    Nicolae ŢÂU

    2017-03-01

    Full Text Available Expanding economic relations and creating an international business environment, international business and the internationalization of the commercial transactions across national borders have become a prerequisite for companies, regardless of the activity they carry. Thus, internationalization is seen as a set of strategic methods, techniques and tools necessary to the companies to function abroad. As the effects of – fiscal and monetary – policies on the global demand and supply are unpredictable in time and space, it appears the requirement to substantiate, develop and put into practice a stabilizing strategy. Besides the indexes showing the evolution of the demand and supply, the market can offer economic agents other analysis and decision parameters as well, such as: economic and financial instruments for influencing the behaviour of the business environment.Obviously, the results depend also on how the authorities (legislative and executive, central and local work for a friendly business environment. There are two mechanisms that can be used for this purpose: fiscal policy (measures to enhance or reduce taxes, dues and public spending initiated by the Government and approved by Parliament; monetary policy (setting the interest rate and the money supply, respectively of the money stock for a specified period of time emitted and monitored (supervised by the National Bank.

  15. Internationalization: an alternative to nuclear proliferation

    International Nuclear Information System (INIS)

    Meller, E.

    1980-01-01

    Leading personalities in the field of nuclear energy worldwide assess possible improvements to the present nonproliferation regime and explore the possibilities for the internationalization of sensitive parts of the nuclear fuel cycle. Their studies address past and current nonproliferation policies, the current controversy between the United States and its European allies on the development of fast breeder reactors and plutonium recycling, implications of the recent US Non-Proliferation Act of 1978 upon US/Euratom relations, industrial government relationships, safety concerns, and the special needs of developing countries. Their conclusions stress the recognition of complex factors such as military security, technical competition, the spread of nuclear technology, and politics that will limit any mechanism to govern nonproliferation. They urge greater effort in educating the public to the political and economic complexities of nuclear power and recommend strengthening international agreements and other arrangements, including controls and safeguards, and the general rules for the international trade of nuclear fuel. 11 figures, 7 tables

  16. Internationalization and technological catching up of emerging multinationals : a case study of China's Haier group

    NARCIS (Netherlands)

    Duysters, G.M.; Jacob, J.; Lemmens, C.E.A.V.; Yu, Jintian

    2009-01-01

    A number of firms from China and India have in recent years been demonstrating their ability to face up to the challenges of globalization by internationalizing their operations. In this article we carry out a case study of China's Haier Group followed by a comparison of its growth and

  17. Policy Internationalization, National Variety and Governance: Global Models and Network Power in Higher Education States

    Science.gov (United States)

    King, Roger

    2010-01-01

    This article analyzes policy convergence and the adoption of globalizing models by higher education states, a process we describe, following Thatcher (2007), as policy internationalization. This refers to processes found in many policy domains and which increasingly are exemplified in tertiary education systems too. The focus is on governmental…

  18. Political perspectives of relationship networks to internationalization of firms in an emerging economy

    Directory of Open Access Journals (Sweden)

    Jefferson Marlon Monticelli

    2017-08-01

    Full Text Available The neo-institutional theory has been used to explain inter-organizational networks related phenomena from the economic and sociological perspectives. The political perspective has not been often used to study institutional contexts of networks. We aim to analyze the decision-making of the formal institutions in the internationalization process of firms in an emerging economy from a political bias. For the empirical field of study, we considered the Brazilian wine industry. Starting from a case study with twenty-three interviews with representatives of wineries and entities of this industry, our paper furthers the understanding of how institutions influence the internationalization of firms in an emerging economy. Based on the political perspective of the neo-institutional theory, our study describes how institutions, mainly the government, can influence an industry. Government cannot afford resources to benefit or protect all the industries, as well as cannot provide incentives to all firms, and those that are supported will lose competitiveness. For the firms, the choices are based on trying to achieve economic advantages through political influences. For the institutions, the choices are based on political influences considering institutional strategies.

  19. Smoke Inhalation and Cyanide Poisoning: 20 Years of Paris Experience

    International Nuclear Information System (INIS)

    Baud, F. J.

    2007-01-01

    Hydroxocobalamin has been used as a cyanide poisoning antidote for many years in France. It has recently been approved by the US FDA. In Paris, hydroxocobalamin is carried by the Brigade de Sapeurs Pompiers (Paris Fire Brigade) in mobile intensive care vehicles and has been administered empirically to victims of enclosed-space fire smoke inhalation who meet the criteria of having soot in the nose, mouth, or throat, any alteration in mental status or disturbance in consciousness, and especially if any degree of hypotension is present (BP less than or equal to 100 mmHg systolic). The administration of hydroxocobalamin at the scene was shown to be safe. Hydroxocobalamin has also been efficacious and safe in 'pure' cyanide poisoning, as long as brain death has not already occurred. A 'toxidrome' of cyanide poisoning has been developed in our institution in Paris, and its application can assist in making the diagnosis of this life-threatening poisoning which cannot be emergent diagnosed by currently-available laboratory methods.(author)

  20. Oxidation of triclosan by permanganate (Mn(VII)): importance of ligands and in situ formed manganese oxides.

    Science.gov (United States)

    Jiang, Jin; Pang, Su-Yan; Ma, Jun

    2009-11-01

    Experiments were conducted to examine permanganate (Mn(VII); KMnO(4)) oxidation of the widely used biocide triclosan (one phenolic derivative) in aqueous solution at pH values of 5-9. Under slightly acidic conditions, the reactions displayed autocatalysis, suggesting the catalytic role of in situ formed MnO(2). This was further supported by the promoting effects of the addition of preformed MnO(2) colloids on Mn(VII) oxidations of triclosan and two other selected phenolics (i.e., phenol and 2,4-dichlorophenol), as well as p-nitrophenol which otherwise showed negligible reactivity toward Mn(VII) and MnO(2) colloids, respectively. Surprisingly, phosphate buffer significantly enhanced Mn(VII) oxidation of triclosan, as well as phenol and 2,4-dichlorophenol over a wide pH range. Further, several other selected ligands (i.e., pyrophosphate, EDTA, and humic acid) also exerted oxidation enhancement, supporting a scenario where highly active aqueous manganese intermediates (Mn(INT)(aq)) formed in situ upon Mn(VII) reduction might be stabilized to a certain extent in the presence of ligands and subsequently involved in further oxidation of target phenolics, whereas without stabilizing agents Mn(INT)(aq) autodecomposes or disproportionates spontaneously. The effectiveness of Mn(VII) for the oxidative removal of triclosan in natural water and wastewater was confirmed. Their background matrices were also found to accelerate Mn(VII) oxidation of phenolics.