Korea-France Forum on New Technologies for Energy

International Nuclear Information System (INIS)

Chang, Jong Hwa; Shin, Young Joon; Kim, Yong Wan

2007-07-01

In celebration of the 120th anniversary on Korea-France diplomatic relations, both Korea and France agreed that the New-generation Energy Forum on a VHTR-assisted nuclear hydrogen production, renewable energy, and bio-fuel should be held in Paries, France. In accordance with the agreement, the Korea-France Forum on New Technologies for Energy organized by KAERI and CEA was held at the Mercure Hotel Conference Hall in Paries for a couple of days, November 6 and 7 and a facility visit to the CEA-Saclay was arranged on November 8 by the French side. 19 scientists from both countries presented their R and D status and plans in 4 technical sessions of 'VHTR Nuclear System', 'VHTR-assited Hydrogen Production', 'Renewable Energy', and 'Fuel Cell and Energy Storage'. A contact point in each field was established for the exchange of technological information and dispatch of experts if necessary

History of psychosurgery at Sainte-Anne Hospital, Paris, France, through translational interactions between psychiatrists and neurosurgeons.

Science.gov (United States)

Zanello, Marc; Pallud, Johan; Baup, Nicolas; Peeters, Sophie; Turak, Baris; Krebs, Marie Odile; Oppenheim, Catherine; Gaillard, Raphael; Devaux, Bertrand

2017-09-01

Sainte-Anne Hospital is the largest psychiatric hospital in Paris. Its long and fascinating history began in the 18th century. In 1952, it was at Sainte-Anne Hospital that Jean Delay and Pierre Deniker used the first neuroleptic, chlorpromazine, to cure psychiatric patients, putting an end to the expansion of psychosurgery. The Department of Neuro-psychosurgery was created in 1941. The works of successive heads of the Neurosurgery Department at Sainte-Anne Hospital summarized the history of psychosurgery in France. Pierre Puech defined psychosurgery as the necessary cooperation between neurosurgeons and psychiatrists to treat the conditions causing psychiatric symptoms, from brain tumors to mental health disorders. He reported the results of his series of 369 cases and underlined the necessity for proper follow-up and postoperative re-education, illustrating the relative caution of French neurosurgeons concerning psychosurgery. Marcel David and his assistants tried to follow their patients closely postoperatively; this resulted in numerous publications with significant follow-up and conclusions. As early as 1955, David reported intellectual degradation 2 years after prefrontal leucotomies. Jean Talairach, a psychiatrist who eventually trained as a neurosurgeon, was the first to describe anterior capsulotomy in 1949. He operated in several hospitals outside of Paris, including the Sarthe Psychiatric Hospital and the Public Institution of Mental Health in the Lille region. He developed stereotactic surgery, notably stereo-electroencephalography, for epilepsy surgery but also to treat psychiatric patients using stereotactic lesioning with radiofrequency ablation or radioactive seeds of yttrium-90. The evolution of functional neurosurgery has been marked by the development of deep brain stimulation, in particular for obsessive-compulsive disorder, replacing the former lesional stereotactic procedures. The history of Sainte-Anne Hospital's Neurosurgery Department sheds

From Penrith to Paris

Directory of Open Access Journals (Sweden)

Katherine Elizabeth Clay

2006-09-01

Full Text Available Katherine Clay has written her first graphic novel, 'From Penrith to Paris', based on experiences of her first semester in France. It deals with the issues of student life, the loss of cultural identity through language and what it means to come from the cultural wasteland of Sydney to the cultural capital of the world - Paris. Through these funny and often life changing experiences, she realises the value of her hometown and that culture, no matter how it is perceived, plays an enormous role in the shaping of individuals.

Korea-France Forum on New Technologies for Energy

Energy Technology Data Exchange (ETDEWEB)

Chang, Jong Hwa; Shin, Young Joon; Kim, Yong Wan

2007-07-15

In celebration of the 120th anniversary on Korea-France diplomatic relations, both Korea and France agreed that the New-generation Energy Forum on a VHTR-assisted nuclear hydrogen production, renewable energy, and bio-fuel should be held in Paries, France. In accordance with the agreement, the Korea-France Forum on New Technologies for Energy organized by KAERI and CEA was held at the Mercure Hotel Conference Hall in Paries for a couple of days, November 6 and 7 and a facility visit to the CEA-Saclay was arranged on November 8 by the French side. 19 scientists from both countries presented their R and D status and plans in 4 technical sessions of 'VHTR Nuclear System', 'VHTR-assited Hydrogen Production', 'Renewable Energy', and 'Fuel Cell and Energy Storage'. A contact point in each field was established for the exchange of technological information and dispatch of experts if necessary.

7TH Annual Anesthesia and Critical Care Symposium (7th) Held in Paris (France) on 22-24 April 1994,

Science.gov (United States)

1994-09-30

Amphitheatre Poincare DIMANCHE 24 AVRIL / SUNDAY APRIL 24th TRAUMATISME CRANIEN CHEZ L’ENFANT HEAD TRA UMA IN CHILDREN Mod6rateurs : J. BERMAN (Winston...Salem, Etats-Unis), Ph. MEYER (Paris, France) 08h30 Epid6miologie et physio-pathologie des traumatismes craniens chez 1’enfant Epidemiology and...pathophysiology of head injuries in children P. OAKLEY (Staffordshire, Royaume-Uni) 09h00 R6animation pr6-hospitali~re du traumatisme cranien grave

[Violence for educational purpose: Representations of general practitioners in the Paris area, France. A qualitative study].

Science.gov (United States)

de Brie, Claire; Piet, Emmanuelle; Chariot, Patrick

2018-03-01

Violence for educational purpose refers to a modality of education that includes threats, verbal abuse, physical abuse and humiliations. Twenty European countries, not including France, have abolished corporal punishment through explicit laws and regulations. The position of general practitioners in the screening and care of violence for educational purpose in France is unknown. In this study, we aimed to assess the representations of this form of violence among general practitioners. We have performed semi-directed interviews of general practitioners in the Paris, France region (Île-de-France). Interviews were conducted until data saturation was achieved. Interviews were recorded, transcribed and analysed by two investigators. Interviews were conducted with 20 physicians (November 2015-January 2016). General practitioners considered that physical, verbal or psychological abuse had possible negative consequences on children. Uncertainty regarding the consequences of violence was a cause of tolerance towards violence for educational purpose, depending on the act committed and the context, as perceived by nearly all practitioners. General practitioners expressed interest in the field. They cited their own education and experience as the main obstacles to action. Most of them expressed a feeling of failure when they screened or took care of violence for educational purpose. This study suggests that doctors can participate in supporting the parents in the prevention of violence for educational purpose. Support to parents would need specific medical training as well as a societal change. Copyright © 2018 Elsevier Masson SAS. All rights reserved.

Feasibility of CO2 storage in geothermal reservoirs example of the Paris Basin - France. Final report

International Nuclear Information System (INIS)

Barbier, J.; Robelin, C.; Kervevan, C.; Thiery, D.; Menjoz, A.; Matray, J.M.; Cotiche, C.; Herbrich, B.

2003-01-01

This study is realized in the framework of GESCO project, which aims to provide the first documentation that, for emission sources within selected key areas, sufficient geological storage capacity is available. Then the BRGM/ANTEA/CFG took care to provide: an inventory of the CO 2 emitters in France, an inventory of the main deep aquifers present in the Paris basin, an evaluation of the storage capacities of CO 2 in one of the four principal case-study, technical solutions for CO 2 injection in geothermal aquifers and an evaluation of the cost of CO 2 storage in such an aquifer. (A.L.B.)

Influence of the water quality improvement on fish population in the Seine River (Paris, France) over the 1990-2013 period.

Science.gov (United States)

Azimi, Sam; Rocher, Vincent

2016-01-15

Over the past 20 years, rules concerning wastewater treatment and quality of water discharged into the environment have changed considerably. Huge investments have been made in Paris conurbation to improve waste water treatment processes in accordance with the European Water Framework Directive. The interdepartmental association for sewage disposal in Paris conurbation (SIAAP) carried out a monitoring of both fish assemblages and water quality in the Seine River around the Paris conurbation (France) since the early 90's. The main goal of this study was to estimate the influence of the water quality improvement on fish. On one hand, the study confirmed the improvement of the water quality (dissolved oxygen, ammonia nitrogen, organic matter) in the Seine River, mostly focused downstream of Paris conurbation. On the other hand, an increase of the number of species occurred from 1990 (14) to 2013 (21). Moreover, changes in the river Seine assemblages happened over that 23-year period with emergence of sensitive species (ruffe, scalpin and pike-perch). The improvement of the water quality was also reported with respect to the Index of Biotic Integrity (IBI). However, no variation of pollutant concentrations in roach, eel and chub muscles has been observed. An exceedance of the environmental quality standards have even been reported all over this period as regards mercury and organochlorine.

Messier, Copernicus, Flamsteed: The SAF Rare-Book Collection in Paris

Science.gov (United States)

Pasachoff, Jay M.

2014-01-01

The historic books belonging to the Société Astronomique de France, founded by Camille Flammarion in 1887, are located partly in Paris and partly at the Flammarion site in Juvisy, a Paris suburb. Their holdings include first editions of Copernicus's De Revolutionibus and of Flamsteed's star atlas, as well as Messier's own copy of his 1783 and 1784 papers with his handwritten comments and additions. I will describe the fruitless search for a Bevis atlas and the circumstances that led me to inspect these treasures. I thank David Valls-Gabaud and Philippe Morel of the Société Astronomique de France for their hospitality in Paris, Jean-Claude Pecker, and Owen Gingerich for his prior work on Messier's catalogue.

Two clusters of ciguatera fish poisoning in Paris, France, related to tropical fish imported from the French Caribbean by travelers.

Science.gov (United States)

Epelboin, Loïc; Pérignon, Alice; Hossen, Virginie; Vincent, Renaud; Krys, Sophie; Caumes, Eric

2014-01-01

Ciguatera fish poisoning (CFP) is a food-borne illness due to the consumption of reef fish containing pathogenic toxins. CFP is endemic to tropical areas and may be described in travelers in non-endemic areas. We describe two clusters of autochthonous cases of CFP in Paris, France. They were related to two fish caught in Guadeloupe (French West Indies) and consumed in Paris after being air-transported in a cooler. In both cases, fish flesh was analyzed and the presence of ciguatoxins by mouse bioassay (MBA) was confirmed. The first cluster involved eight individuals among whom five presented gastrointestinal symptoms and four presented neurological symptoms after consuming barracuda flesh (Sphyraena barracuda). The second cluster involved a couple who consumed a grey snapper (Lutjanus griseus). Most of them consulted at different emergency departments in the region of Paris. CFP may be seen in non-traveler patients outside endemic countries resulting from imported species of fish. Thus, CFP may be undiagnosed as physicians are not aware of this tropical disease outside endemic countries. The detection of ciguatoxins by MBA in the French National Reference Laboratory is useful in the confirmation of the diagnosis. © 2014 International Society of Travel Medicine.

Understanding the patient multidimensional experience: a qualitative study on coping in hospitals of Assistance Publique-Hôpitaux de Paris, France

Directory of Open Access Journals (Sweden)

Reach G

2015-04-01

Full Text Available Gérard Reach,1 Denis Fompeyrine,2 Carole Mularski21Department of Endocrinology, Diabetes and Metabolic Diseases, Avicenne Hospital APHP and EA 3412, CRNH-IdF, Paris 13 University, Bobigny, France; 2Direction des Patients, Usagers et Associations, Assistance Publique-Hôpitaux de Paris, Paris, FranceObjective: Time spent in hospitals is complex and entails a number of distinct phases that fluctuate depending on many variables. Attempts to understand patients’ experiences often involve focusing on their needs using self-evaluation, but this does not clearly highlight the complexity of coping. Questionnaires based on telephone surveys and emails do not facilitate a sufficient assessment of the coping effort. However, when patients express themselves through spontaneous narration, different dimensions may emerge in their experience at the hospital. This qualitative study explores the various forms of coping among patients with a hospital experience.Methods: Interviews were conducted with 75 patients in six hospital departments. Transcripts from interviews were thematically analyzed and a conceptual, multidimensional model was developed to explain the relationship between patient experience and coping complexity.Results: Patients used a set of about 50 different terms to describe their experiences in the hospital. They described with the greatest number of words the aspects that triggered their stress or distress and forced them to cope. Stress resulting from the experienced situation was classifiable into five dimensions: trauma, environment, medical, interpersonal affective, and social impact, which constitute invariants that may require individual complex coping strategies.Conclusion: Patient experience is hard to evaluate, and this represents a permanent challenge for medical teams. Considering the five coping dimensions delineated in this study may be helpful in improving the patient’s hospital experience.Keywords: patient experience

The meaning of city noises: Investigating sound quality in Paris (France)

Science.gov (United States)

Dubois, Daniele; Guastavino, Catherine; Maffiolo, Valerie; Guastavino, Catherine; Maffiolo, Valerie

2004-05-01

The sound quality of Paris (France) was investigated by using field inquiries in actual environments (open questionnaires) and using recordings under laboratory conditions (free-sorting tasks). Cognitive categories of soundscapes were inferred by means of psycholinguistic analyses of verbal data and of mathematical analyses of similarity judgments. Results show that auditory judgments mainly rely on source identification. The appraisal of urban noise therefore depends on the qualitative evaluation of noise sources. The salience of human sounds in public spaces has been demonstrated, in relation to pleasantness judgments: soundscapes with human presence tend to be perceived as more pleasant than soundscapes consisting solely of mechanical sounds. Furthermore, human sounds are qualitatively processed as indicators of human outdoor activities, such as open markets, pedestrian areas, and sidewalk cafe districts that reflect city life. In contrast, mechanical noises (mainly traffic noise) are commonly described in terms of physical properties (temporal structure, intensity) of a permanent background noise that also characterizes urban areas. This connotes considering both quantitative and qualitative descriptions to account for the diversity of cognitive interpretations of urban soundscapes, since subjective evaluations depend both on the meaning attributed to noise sources and on inherent properties of the acoustic signal.

Breaking Through the n^3 Barrier: Faster Object Type Inference

DEFF Research Database (Denmark)

Henglein, Fritz

1999-01-01

Invited paper selected from 4th Int'l Workshop on Foundations of Object-Oriented Languages (FOOL), January 1997, Paris, France......Invited paper selected from 4th Int'l Workshop on Foundations of Object-Oriented Languages (FOOL), January 1997, Paris, France...

Carmes Polytechnique, Housing in the Heart of Paris Energy renovation of a social housing estate in Paris

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Christian Horn

2017-12-01

Full Text Available The architecture offices Atelier de la Seine and Rethink have been commissioned with the engineers Pouget Consultants by the social landlord Paris Habitat for the extensive renovation of a social housing estate in the historic centre of Paris. The estate has been built in 1930 and integrates a part of the former college of the Lombard build in the 17th century. It belongs to the social housing typology 'Habitations à Bon Marché (HBM' constructed between1894 and 1949. This typology is generally characterized by its integration in its urban context and an apparent brick facade. The renovation project includes a focus on the reduction of the energy consumption. An important subject, as of the total number of 4.6 millions of social housing in France more than 50 % have been build before 1975 (before the first thermal regulation and many are still considered energy-intensive.

Trace metal concentrations in forest and lawn soils of Paris region (France) along a gradient of urban pressure

Science.gov (United States)

Ludovic, Foti

2017-04-01

concentrations and subsequent risks in soils of Paris and Paris region (Île-de-France). Our study aims at filling this knowledge gap, focusing on contamination and pollution by TMs in lawns and forests that constitute the main types of vegetation in urban areas of Paris region. Considering the rational described above, the aims of the present study were (i) to examine the concentration of eight selected TMs (As, Cd, Cr, Cu, Fe, Ni, Pb, Zn) in soils of two land-uses (public lawns and woods) along an urban pressure gradient in Paris region, (ii) to distinguish origins and sources of contamination or pollution, (iii) to evaluate the individual and overall TM contamination degree as well as the individual and overall TM pollution degree, (iiii) to use soil characteristics to better understand soil origins and histories along the urban pressure gradient and the relationship between these characteristics and TM concentrations. Ultimately, this study provides a baseline TM assessment for the long-term monitoring of the evolution of TM soil contents in urban area of the Paris region.

Cost analysis of adverse events associated with non-small cell lung cancer management in France

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Chouaid C

2017-07-01

Full Text Available Christos Chouaid,1 Delphine Loirat,2 Emilie Clay,3 Aurélie Millier,3 Chloé Godard,4 Amira Fannan,4 Laurie Lévy-Bachelot,4 Eric Angevin5 1Chest Department, Centre Hospitalier Intercommunal Créteil, Créteil, France; 2Institut Curie, Paris, France; 3Creativ-Ceutical, Paris, France; 4MSD France, Courbevoie, France; 5Institut Gustave Roussy, Villejuif, France Background: Adverse events (AEs related to medical treatments in non-small cell lung cancer (NSCLC are frequent and need an appropriate costing in health economic models. Nevertheless, data on costs associated with AEs in NSCLC are scarce, particularly since the development of immunotherapy with specific immune-related AEs.Objective: To estimate the costs of grades 3 and 4 AEs related to NSCLC treatments including immunotherapy in France.Methods: Grades 3 and 4 AEs related to treatment and reported in at least 1% of patients in Phase III clinical trials for erlotinib, ramucirumab plus docetaxel, docetaxel, pemetrexed plus carboplatin plus bevacizumab, platinum-based chemotherapies, nivolumab and pembrolizumab were identified. When no cost evaluation was reported in literature, estimates on standard treatments and medical resource use for each AE were obtained thanks to an expert panel. Total cost per AE was calculated from a French national health insurance perspective and updated in 2017 Euros. Hospital stay costs were estimated based on public and private weighted tariffs and data from the French Medical Information System (Programme de Médicalisation des Systèmes d’Information. Costs of tests, consultations and treatments were calculated based on national reimbursement tariffs.Results: Overall, costs of grades 3 and 4 AEs related to treatment ranged from €46 per event to €7,742 per year. Fourteen out of 24 AEs identified had a mean estimated cost over €2,000. The highest mean costs were related to type 1 diabetes (€7,742 per year followed by pneumonitis (€5,786 per event

Preliminary report on AED deployment on the entire Air France commercial fleet: a joint venture with Paris XII University Training Programme.

Science.gov (United States)

Bertrand, C; Rodriguez Redington, P; Lecarpentier, E; Bellaiche, G; Michel, D; Teiger, E; Morris, W; Le Bourgeois, J P; Barthout, M

2004-11-01

The positive effect of early defibrillation on survival from cardiac arrest has been demonstrated. We describe the use of AEDs over 1 year following the training of flight attendants. Air France and the University of Paris XII together designed a 1 year training programme for 14000 flight attendants. The university emergency departments (SAMU) provided 250 instructors. AEDs training and certification was conducted for crew members between November 2001 and November 2002. By January 2003, all aircraft were fully equipped with AEDs. All cases of cardiac arrest that occurred during the study were reviewed comprehensively. Comments from the crew were collected. Twelve cardiac arrests were reported between November 2002 and November 2003 out of 4194 cases of emergency care delivered to passengers. Shock treatment was advised initially in 5/12 cases. The survival rate after in-flight cardiac arrest was 3/12. The survival rate at discharge from hospital following in flight shock was 2/5. No complications arose from the use of AEDs. Training by professionals gave the flight attendants confidence and allowed for the survival of two young passengers. Our study highlights the ability of flight attendants to give better onboard care for the future. The next step is to consolidate the network between in-flight care and the medical dispatch centre in Paris.

A thyrotoxicosis outbreak due to dietary pills in Paris

Directory of Open Access Journals (Sweden)

Vincent Ioos

2008-10-01

Full Text Available Vincent Ioos1, Vincent Das1, Eric Maury1,2, Jean-Luc Baudel1, Jérôme Guéchot3, Bertrand Guidet1,2, Georges Offenstadt1,21Réanimation Médicale; 2Université Pierre et Marie Curie-Paris 6, INSERM, UMR-S 707; 3Unité d’Hormonologie, APHP, Hôpital Saint Antoine, F-75012, Paris, FranceAbstract: Three women were consecutively admitted to our medical intensive care unit for thyrotoxicosis after the ingestion of dietary pills accidentally containing high levels of thyroxin. These cases were observed during an outbreak in the Paris area. Despite similar blood levels of thyroid hormones, their clinical presentation and outcome were very different. One patient developed febrile confusion and died from malignant hyperthermia. The second one had progressive confusion requiring mechanical plasma exchange therapy and had a favorable outcome. The third one had very moderate symptoms. These exceptional observations raise several issues concerning diagnosis, physiopathology and treatment of thyrotoxicosis factitia.Keywords: thyrotoxicosis, dietary pills, thyroxin

Trace element concentrations along a gradient of urban pressure in forest and lawn soils of the Paris region (France).

Science.gov (United States)

Foti, Ludovic; Dubs, Florence; Gignoux, Jacques; Lata, Jean-Christophe; Lerch, Thomas Z; Mathieu, Jérôme; Nold, François; Nunan, Naoise; Raynaud, Xavier; Abbadie, Luc; Barot, Sébastien

2017-11-15

The concentration, degree of contamination and pollution of 7 trace elements (TEs) along an urban pressure gradient were measured in 180 lawn and wood soils of the Paris region (France). Iron (Fe), a major element, was used as reference element. Copper (Cu), cadmium (Cd), lead (Pb) and zinc (Zn) were of anthropogenic origin, while arsenic (As), chromium (Cr) and nickel (Ni) were of natural origin. Road traffic was identified as the main source of anthropogenic TEs. In addition, the industrial activity of the Paris region, especially cement plants, was identified as secondary source of Cd. Soil characteristics (such as texture, organic carbon (OC) and total nitrogen (tot N) contents) tell the story of the soil origins and legacies along the urban pressure gradient and often can explain TE concentrations. The history of the land-use types was identified as a factor that allowed understanding the contamination and pollution by TEs. Urban wood soils were found to be more contaminated and polluted than urban lawns, probably because woods are much older than lawns and because of the legacy of the historical management of soils in the Paris region (Haussmann period). Lawn soils are similar to the fertile agricultural soils and relatively recently (mostly from the 1950s onwards) imported from the surrounding of Paris, so that they may be less influenced by urban conditions in terms of TE concentrations. Urban wood soils are heavily polluted by Cd, posing a high risk to the biological communities. The concentration of anthropogenic TEs increased from the rural to the urban areas, and the concentrations of most anthropogenic TEs in urban areas were equivalent to or above the regulatory reference values, raising the question of longer-term monitoring. Copyright © 2017 Elsevier B.V. All rights reserved.

The Road Transport world exhibition in Paris

International Nuclear Information System (INIS)

Anon.

1995-01-01

Following the agreement between French and German professionals of automobile and industrial vehicle, the Road Transport world exhibition will take place alternatively in Paris and Hanover. The 1995 meeting has taken place in Paris (September 15-21) and about 20 countries were represented. Road transport is the principal way of goods transportation in France and represent 88% of the traffic explained in tons gross and 70% in tons km. The petroleum dependence of the transportation sector is becoming a worrying problem as the gasoline and diesel fuels taxes will be discussed in the 1996 financial laws project. According to the last ''Worldwide energetic perspectives'' report published by the IEA, in 2010 the transportation sector could absorb more than 60% of the worldwide petroleum consumption. This increase represents a challenge to the petroleum industry to increase the energetic efficiency of the vehicle fuels and the production of diesel fuels, and conversely to reduce the pollution effluents. (J.S.). 4 tabs

A simple semipaced 3-minute chair rise test for routine exercise tolerance testing in COPD

Directory of Open Access Journals (Sweden)

Aguilaniu B

2014-09-01

Full Text Available Bernard Aguilaniu,1,2 Hubert Roth,3 Jesus Gonzalez-Bermejo,4 Marie Jondot,5 Jocelyne Maitre,5 François Denis,6 Thomas Similowski4,7 1Medicine Faculty, Université Joseph Fourier, Grenoble, France; 2McGill University, Montreal, Canada; 3Centre de Recherche en Nutrition Humaine Rhône-Alpes, CHU Grenoble, France; 4Assistance Publique-Hôpitaux de Paris, Groupe Hospitalier Pitié-Salpêtrière, Respiratory and Intensive Care Medicine, Paris, France; 5Clinique Universitaire de Pneumologie, CHU Grenoble, France, Grenoble, France; 6Boehringer Ingelheim, 7Université Paris, Paris, France Abstract: The functional work capacity of chronic obstructive pulmonary disease (COPD patients is usually assessed with walk tests such as the 6-minute walk test (6MWT or the shuttle test. Because these exercise modalities require a controlled environment which limits their use by pulmonologists and severely restricts their use among general practitioners, different modalities of a short (1 minute or less sit-to-stand test were recently proposed. In this study, we evaluated a new modality of a semipaced 3-minute chair rise test (3CRT in 40 patients with COPD, and compared the reproducibility of physiological responses and symptoms during the 3CRT and their interchangeability with the 6MWT. The results demonstrate that physiological variables, heart rate, pulse oxygen saturation, work done, and symptoms (Borg dyspnea and fatigue scores, during the 3CRT were highly reproducible, and that the physiological responses and symptoms obtained during the 3CRT and the 6MWT were interchangeable for most patients. Moreover, these preliminary data suggest that patients able to perform more than 50 rises during 3 minutes had no significant disability. The simplicity and ease of execution of the 3CRT will facilitate the assessment of exercise symptoms and disability in COPD patients during routine consultations with pulmonologists and general practitioners, and will thus contribute

Sequence stratigraphy and tectonosedimentary history of the Upper Jurassic of the Eastern Paris Basin (Lower and Middle Oxfordian, Northeastern France)

Science.gov (United States)

Carpentier, Cédric; Lathuilière, Bernard; Ferry, Serge; Sausse, Judith

2007-04-01

In the present study, the difficulty which lies in the identification of sea-level fall discontinuities in deep depositional environments led the authors to use the transgressive surfaces (i.e. the most noticeable surfaces in the present case) to determine depositional cycles. Four (3rd order?) Lower and Middle Oxfordian cycles were identified (S1, S2, S3, and S4) in the Eastern Paris Basin. These four cycles can be organised into two lower frequency cycles (So I and So II) which comprise the S1, S2 and the S3, S4 cycles respectively. During the time intervals of the S1, S2, and S3 cycles, sedimentation occurred along a southward dipping carbonate-siliciclastic ramp, prograding from the northern Ardennes area. The S4 cycle shows the development of a reefal distally steepened ramp which subsequently evolved into a flat-topped platform as a result of the compensation infill of the available accommodation space by the carbonate production during a climatic warming, in this case reef growth. Isopach and facies maps suggest synsedimentary activities of hercynian faults coevals with the floodings of the So I and So II cycles. One of these events generated a diachronism of the maximum flooding (Plicatilis Zone) during the So II cycle between the northwestern and southeastern parts of the studied area. The depositional patterns found in the Eastern Paris Basin and the Swiss Jura show great similarities for the Early-Middle Oxfordian. Both regions were probably connected and recorded the same tectonosedimentary evolution. In contrast a tectonic control certainly generated differences between the sequence-stratigraphic framework of the Eastern Paris Basin and the eustatic chart.

Circulation of Pneumocystis dihydropteroate synthase mutants in France.

Science.gov (United States)

Le Gal, Solène; Damiani, Céline; Perrot, Maëla; Rouillé, Amélie; Virmaux, Michèle; Quinio, Dorothée; Moalic, Elodie; Saliou, Philippe; Berthou, Christian; Le Meur, Yann; Totet, Anne; Nevez, Gilles

2012-10-01

Data on the prevalence of Pneumocystis jirovecii (P. jirovecii) dihydropteroate synthase (DHPS) mutants in France are still limited. In this study, mutant prevalence in the Brest region (western France) was determined. Archival pulmonary specimens from 85 patients infected with P. jirovecii and admitted to our institution (University Hospital, Brest) from October 2007 to February 2010 were retrospectively typed at the DHPS locus using a polymerase chain reaction-restriction fragment length polymorphism assay. Type identification was successful in 66 of 85 patients. Sixty-four patients were infected with a wild type, whereas mutants were found in 2 patients (2/66, 3%). Medical chart analysis revealed that these 2 patients usually lived in Paris. Another patient usually lived on the French Riviera, whereas 63 patients were from the city of Brest. Thus, the corrected prevalence of mutants in patients who effectively lived in our geographic area was 0% (0/63). Taking into account that i) Paris is characterized by a high prevalence of mutants from 18.5% to 40%, ii) infection diagnoses were performed in the 2 Parisians during their vacation Paris to Brest through infected vacationers. The study shows that the usual city of patient residence, rather than the city of infection diagnosis, is a predictor of mutants and that P. jirovecii infections involving mutants do not represent a public health issue in western France. Copyright © 2012 Elsevier Inc. All rights reserved.

Paris-Nairobi Conference - Proceedings

International Nuclear Information System (INIS)

2011-04-01

response to ECOWAS energy needs (M. Kappiah, ECREE); 3 - Energy access, sustainable development and climate change: the Gabon experience (R. Immongault); 4 - Presentation of the Vergnet Group, Wind Turbine, Water pumps and Solar systems installer; 5 - Indicators for the selection of projects to climate-proof energy systems (H. Connor, Helio International); 6 - Presentation of the Paris-Nairobi Climate Initiative by the International Energy Agency (F Birol, IEA); 7 - Presentation of the Japan's Cooperation for Energy Infrastructure (1 slide only); 8 - JICA's Experience in Energy Sector Development (Kyoko Kuwajima, Japan International Cooperation Agency); 9 - Presentation of Lake Turkana Wind Power project; 10 - The global rural electrification programme of Morocco (A. Benkhadra); 11 - Presentation of the Qatar National Food Security Programme (1 slide only); 12 - Developing access to energy (G. Vermot Desroches, Schneider Electric)

New characterization aspects of carbonate accumulation horizons in Chalky Champagne (NE of the Paris Basin, France)

Science.gov (United States)

Linoir, Damien; Thomachot-Schneider, Céline; Gommeaux, Maxime; Fronteau, Gilles; Barbin, Vincent

2016-05-01

The soil profiles of the Champagne area (NE of Paris Basin, France) occasionally show carbonate accumulation horizons (CAHs). From the top to the bottom, these soil profiles include a rendic leptosol horizon, a Quaternary cryoturbated paleosol (QCP), and a chalky substratum. The CAHs are located in the top part of the QCP. This study is aimed at highlighting the specific characteristics of CAHs compared to other soil profile horizons using geophysics, geochemistry, micromorphology, and mercury injection porosimetry. It is the first essential step for understanding the impact of CAHs on water transfers into the Champagne soil profiles. Our analyses show that Champagne CAHs are not systematically characterized by a typical induration unlike generally put forward in the regional literature. They are more porous and heterogeneous than their parent material (QCP). Carbonate accumulation horizons are also characterized by singular colorimetric parameters that are linked to their geochemical specific content, even if they bear a signature of the initial QCP before the pedogenic modification.

Communication dated 26 November 2004 received from the Permanent Representatives of France, Germany, the Islamic Republic of Iran and the United Kingdom concerning the agreement signed in Paris on 15 November 2004

International Nuclear Information System (INIS)

2004-01-01

The Director General has received a letter dated 26 November 2004 from the Permanent Representatives of France, Germany, the Islamic Republic of Iran and the United Kingdom, attaching the text of the agreement signed by the Governments of France, Germany, the United Kingdom of Great Britain and Northern Ireland with the support of the High Representative of the European Union, and the Islamic Republic of Iran, in Paris on 15 November 2004. The letter and, as requested therein, the text of the agreement, is reproduced herewith for the information of Member States

Infestation by pyrethroids resistant bed bugs in the suburb of Paris, France

Directory of Open Access Journals (Sweden)

Durand R.

2012-11-01

Full Text Available Bed bugs are hematophagous insects responsible for a re-emerging and challenging indoor pest in many countries. Bed bugs infestations may have health consequences including nuisance biting, cutaneous and systemic reactions. This resurgence can probably be attributed to factors such as increased international travel and development of resistance against insecticides. Resistance against pyrethroids has been reported several times from the USA and rarely in Europe. In France, very few data on bed bugs are available. The present study aimed to assess the infestation by bed bugs of a complex of two high-rise apartment buildings in the suburb of Paris and to evaluate their susceptibility to pyrethroid insecticides. We inspected for bed bugs 192 out of 198 apartments units (97% and interviewed their residents. 76 (39.6% apartments were infested. Among the 97 residents living in infested apartments, 53 (54.6% reported bed bug bites. A total of 564 bed bugs were collected in the infested units. Bioassays showed that 54 out of 143 bed bugs were resistant to pyrethroids (37.8%; 95% confidence interval: 29.9-45.7%. DNA sequencing showed that all bed bugs tested (n = 124 had homozygous L925I kdr-like gene mutation. The level of pyrethroid resistance found indicates that this phenomenon was already established in the site and prompts the need to reevaluate the wide use of pyrethroids to control bed bugs.

Health-resource use and costs associated with fibromyalgia in France, Germany, and the United States

Directory of Open Access Journals (Sweden)

Chandran A

2013-04-01

Full Text Available Tyler Knight,1 Caroline Schaefer,1 Arthi Chandran,2 Gergana Zlateva,2 Andreas Winkelmann,3 Serge Perrot4 1Health Economics and Outcomes Research, Covance Market Access Services, Gaithersburg, MD, USA; 2Primary Care Health Economics and Outcomes Research, Pfizer Global Health Economics, New York, NY, USA; 3Department of Physical Medicine and Rehabilitation, University Hospital Munich, Munich, Germany; 4Service de Médecine Interne et Thérapeutique, Université Paris Descartes, Paris, France Background: Fibromyalgia (FM is a chronic disorder characterized by widespread, persistent pain. Prospective and retrospective studies have demonstrated substantial health-care costs associated with FM in a number of countries. This study evaluated and compared health-resource use (HRU and associated costs related to FM in routine clinical practice across the US, France, and Germany. Methods: Two separate, cross-sectional, observational studies of subjects with FM were conducted: one in the US and one in France and Germany. HRU related to prescription medication, physician office visits, diagnostic tests, and hospitalizations was abstracted from chart review; patient out-of-pocket costs and lost productivity were collected via subject self-report. Costs were assigned to HRU based on standard algorithms. Direct and indirect costs were evaluated and compared by simple linear regression. Results: A total of 442 subjects (203 US, 70 France, 169 Germany with FM were analyzed. The mean (standard deviation age in the US, France, and Germany was 47.9 (10.9, 51.2 (9.5, and 49.2 (9.8, respectively (P = 0.085. Most subjects were female (95% US, 83% France, 80% Germany (P < 0.001. Adjusted annual direct costs per subject for FM were significantly higher in the US ($7087 than in France ($481, P < 0.001 or Germany ($2417, P < 0.001. Adjusted mean annual indirect costs per subject for FM were lower in the US ($6431 than in France ($8718 or Germany ($10,001, but represented

Load curve impact of large electric vehicles fleet in the Paris Ile-de-France region

OpenAIRE

Assoumou , Edi; Marmorat , Jean-Paul; Houel , Jérôme; Roy , Valérie

2015-01-01

The EV-STEP project was carried out within the ERANET+ Electromobility framework. Funding for the research work presented in this paper by the French Ministry of Ecology, Sustainable Development and Energy is gratefully acknowledged. Complementary support was provided by the Chair Modeling for sustainable development, driven by MINES ParisTech, Ecole des Ponts ParisTech, and AgroParisTech; supported by ADEME, EDF, GRTgaz, Schneider Electric and the Ministry of Ecology, Sustainable Development...

Milnacipran and venlafaxine at flexible doses (up to 200 mg/day) in the outpatient treatment of adults with moderate-to-severe major depressive disorder: a 24-week randomized, double-blind exploratory study

OpenAIRE

Briley, Mike

2010-01-01

Jean-Pierre Olié1, David Gourion2, Agnès Montagne3, Michel Rostin4, Marie-France Poirier11Service de Santé Mentale et Thérapeutique, Centre Hospitalier Sainte-Anne, Paris, France; 217 rue des Marronniers, 75016 Paris, France; 3Pierre Fabre Médicament, Labège, France; 4Pierre Fabre Médicament, Castres, FranceAbstract: The objective of this exploratory, multicenter, randomized, double-blind study, was to evaluate the e...

[Management of wheezing disorders in infants participating in the PARIS birth cohort].

Science.gov (United States)

Herr, M; Nikasinovic, L; Foucault, C; Le Marec, A M; Giordanella, J P; Just, J; Momas, I

2012-01-01

While wheezing disorders are common in preschool children, their management is not well defined. The aim of this study was to assess the use of medical health care resources due to wheezing disorders in infants aged 18 months followed up in the Pollution and Asthma Risk: an Infant Study (PARIS) birth cohort. Data on wheezing disorders, medical visits and medication on account of respiratory disorders during the previous 12 months were collected with a standardized questionnaire, administered by a paediatrician, during the health check offered to every child aged 18 months included in the PARIS birth cohort. The prevalence of wheezing disorders during the past 12 months amounted to 560/1974 (28.4%). Among wheezers, 493 (89.3%) required a medical visit because of difficult breathing; 61 (11.0%) went to the emergency room, 35 (6.4%) were admitted to the hospital and 375 (67.2%) received an inhaled anti-asthmatic medication. Recourse to chest physiotherapy was reported in 472 of them (85.1%). This study confirms the high use of healthcare resources because of wheezing disorders in infants and suggests a higher use of anti-asthmatic medications in France compared to other European countries. Copyright © 2011 SPLF. Published by Elsevier Masson SAS. All rights reserved.

The social aspects in the identification of children’s mental health problems in two health services in Paris, France

Directory of Open Access Journals (Sweden)

Eunice Nakamura

2017-06-01

Full Text Available Children’s mental health problems were analyzed from a sociological approach addressing two questions: what are the main children’s behaviors identified and considered to be mental health problems, and what are the consequences of this classification for the debate on children’s problems in contemporary societies. This quantitative and qualitative study analyzed 275 patients’ records from two child mental health services (CMHS in the northeast area of Paris, France. The majority of children were boys from six to 11 years old; requests were presented mainly by schools and parents; the main problems were behavioural problems, cognitive difficulties and relational problems (boys, and affective or emotional problems (girls. There is an interdependence of a great number of actors who worry about children’s behavior and a system of expectations seems to be collectively woven by them as social classifications.

Pain associated with health and economic burden in France: results from recent National Health and Wellness Survey data

Directory of Open Access Journals (Sweden)

Hadjiat Y

2018-01-01

Full Text Available Yacine Hadjiat,1 Alain Serrie,2 Richard Treves,3 Berangere Chomier,1 Laurent Geranton,4 Stephane Billon5 1Medical Department, Mundipharma SAS, Paris, 2Pain and Palliative Care Department, CHU Lariboisiere, Paris, 3Rheumatology Department, CHU Limoges, Limoges, 4Public Affairs Department, Mundipharma, 5Department of Health Economics, University Paris Dauphine, Paris, France Purpose: This study aimed to estimate the prevalence of pain among French adults and assess the impact of pain on health-related quality of life (HRQoL, activity impairment, and health care resource use (HRU.Patients and methods: Respondents from the 2015 France National Health and Wellness Survey (N=19,173 were categorized by self-reported pain (experienced pain in the past 12 months vs no pain and compared on HRQoL (36-Item Short Form Health Survey version 2: Mental Component Summary, Physical Component Summary, and Short Form-6 Dimensions health utilities, activity impairment (Work Productivity and Activity Impairment questionnaire, employment status, and HRU (health care provider visits, emergency room visits, and hospitalizations. Bivariate analyses examined differences between pain groups stratified by age, sex, income, and Charlson comorbidity index (CCI scores.Results: Pain prevalence was 20.2% (n=4007. Mean Physical Component Summary decrements with pain ranged from 3.4 to 8.1 points among those aged <35 years to those aged 45–54 years, respectively. Results for Mental Component Summary and Short Form-6 Dimensions scores followed similar patterns. Regardless of income, sex, or CCI group, pain was associated with significant decrements on all HRQoL measures (for all, p<0.05. The impact of pain on activity impairment was lowest among those <35 years; this impact was higher in middle age and then tapered off among those aged ≥75 years. Pain was associated with greater activity impairment and more health care provider visits across income, sex, and CCI groups (for all

Les mauvais rêves. Une prison à Disneyland Paris

OpenAIRE

Genetelli, Olivier

2011-01-01

Situé à 35 km de Paris, dans la nouvelle ville de Marne-La-Vallée, Disneyland Paris représente la première destination de loisirs d'Europe. L'implantation du “rongeur aux grande oreilles” ne s'est pas contentée d'établir un simple parc à thème, mais elle a cherché à imposer un cadre de vie sur toute une partie du territoire français, à travers un partenariat public-privé unique en France. De ce fait, nous nous retrouvons dans un “territoire-bulle” contrôlé par Disney. Tout y est propre, sécur...

[Defusing of victims of the terrorist attacks in Paris. Elements of assessment one-month post-event].

Science.gov (United States)

Prieto, N; Cheucle, E; Faure, P; Digard, F; Dalphin, C; Pachiaudi, V; Simond, M; Darbon, R; Collinet, C; Habibi, R; Gueugniaud, P-Y

2018-04-01

The terrorist attacks (fusillades and suicide attacks) in Paris on 13 November 2015 have had a major psychic impact on all individuals directly or secondarily exposed to them. Medico-psychological unit (CUMP) of the Paris Île-de-France region's immediate care services were immediately mobilized and rapidly strengthened by all regional medico-psychological units (CUMP) throughout the country. Psychological assistance has been provided in several key points of Paris and specifically in the 11th district City Hall of Paris where Lyon's Medico-psychological unit was located. These specific immediate psychological assistances, referred to as a "defusing process" by the medico-psychological unit (CUMP), are mostly devoted to provide the victims with an entry point to a psychological healthcare relationship and give them a first sense of soothing and relief even though they do not prevent further psychological care follow up for the victims. Nonetheless, the potential therapeutic effect of this "defusing process" has not yet been sufficiently established nor demonstrated by any scientific study. A phoning survey was carried out one-month post-terrorist attacks and interviewed the 129 victims who benefited from the "defusing process" conducted by Lyon's medico-psychological unit (CUMP) in order to collect data and assess its effects. These people, whether directly exposed, bereaved relatives or witnesses, whose average age is 35, are mostly living in the Île-de-France region. Most of them present a high score on the IES-R scale, whether they were directly exposed, bereaved relatives or witnesses. Almost all of them (96.5%) experienced at least one medical care contact within this one-month post-trauma period with psychotropic medication for 37% of them. Regarding the defusing conducted by Lyon's medico-psychological unit (CUMP) in the 11th district City Hall of Paris, it appears that 93% of the victims who were looked after indicated that they were satisfied and 87.4% of

Urban dew and rain in Paris, France: Occurrence and physico-chemical characteristics

Science.gov (United States)

Beysens, D.; Mongruel, A.; Acker, K.

2017-06-01

This paper summarizes one year (April 2011 to March 2012) measurements on planar condensing surfaces of dew and rain events and related physico-chemical characteristics in the urban environment of Paris (city center). Yearly collected water was 3.48 mm for dew (63 events) and 593 mm for rain (146 events). The latter value compares well with rain data (547 mm and 107 events) collected within 12 km at Paris-Orly airport. An estimation of dew yield based on meteo data gives 2.35 mm and 74 events, to be compared with 17.11 mm and 196 events at Paris-Orly. These differences highlight the large reduction in dew events and dew yields in an urban area as compared to a close rural-like area. This reduction is not due to a sky view reduction but to heat island that increases air temperature and decreases relative humidity. Analysis of dew (34) and rain (77) samples were done concerning pH, electrical conductivity (EC), major anions and cations as well as selected trace metals and other minor ions. Mean pH values are found similar for both, dew (6.5) and rain (6.1), rain being slightly more acidic than dew. The mean dew total ionic content (TIC 1.8 meq/l) and EC value (124 μS/cm) are about four times that of rain (0.45 meq/l; 35 μS/cm), meaning that total dissolved solids in dew is nearly four times that in rain. Sulfate and nitrate are the most acidifying components, calcium the most neutralizing constituent with ratio of mean total acidity/total alkalinity comparable for dew and rain ( 0.9). Sulfate and nitrate have mainly anthropogenic sources, whereas chloride and magnesium are mostly connected with marine air masses. Dew is a considerable factor of wet deposition of pollutants; dew and rain ion concentrations, however, meet the WHO requirements for drinking water.

Three centuries of heavy metal pollution in Paris (France) recorded by urban speleothems

Energy Technology Data Exchange (ETDEWEB)

Pons-Branchu, Edwige, E-mail: epons@lsce.ipsl.fr [LSCE (UMR8212, CEA/CNRS/UVSQ), Bâtiment 12, avenue de la Terrasse, 91198 Gif-Sur-Yvette (France); Ayrault, Sophie; Roy-Barman, Matthieu; Bordier, Louise [LSCE (UMR8212, CEA/CNRS/UVSQ), Bâtiment 12, avenue de la Terrasse, 91198 Gif-Sur-Yvette (France); Borst, Wolfgang; Branchu, Philippe [CEREMA, 12 rue Teisserenc de Bort, 78190 Trappes (France); Douville, Eric [LSCE (UMR8212, CEA/CNRS/UVSQ), Bâtiment 12, avenue de la Terrasse, 91198 Gif-Sur-Yvette (France); Dumont, Emmanuel [CEREMA, rue de l' égalité Prolongée, 93352, Le Bourget cedex 319 (France)

2015-06-15

The first record of urban speleothems used to reconstruct the history of heavy metal pollution of shallow groundwaters is presented. Two speleothems grew during the last 300 years in an underground aqueduct in the north-eastern part of Paris. They display high Pb, Mn V, Cu, Cd and Al concentrations since 1900 due to the urbanization of the site which triggered anthropogenic contamination of the water feeding the speleothems. Surprisingly, these heavy metal concentrations are also high in the oldest part. This early pollution could come from the use of Parisian waste as fertilizers in the orchards and vineyards cultivated above the aqueduct before urbanization. Lead isotopes were measured in these carbonates as well as in lead artifacts from the 17th–18th centuries ({sup 206}Pb/{sup 207}Pb = 1.180 +/− 0.003). The mean {sup 206}Pb/{sup 207}Pb ratio, for one of the speleothems is 1.181 +/− 0.003 unvarying with time. These lead signatures are close to those of coal and old lead from northern European mines, lower than the natural background signature. It confirms that the high metal concentrations found come from anthropogenic pollution. Conversely, the lead isotopic composition of the second speleothem presents two temporal trends: for the oldest levels, the mean value (1.183 +/− 0.003) is similar to the first speleothem. For the youngest part, a lower value (1.172 +/− 0.005) is recorded, evidencing the contribution of a new lead source at the beginning of the industrial revolution. Pb isotopes were also measured in recent samples from a nearby superficial site. The first sample is a recent (AD 1975 +/− 15 years) deposit ({sup 206}Pb/{sup 207}Pb = 1.148 +/− 0.003), and the second, a thin subactual layer ({sup 206}Pb/{sup 207}Pb = 1.181 +/− 0.002). These data are compatible with the adding of anthropogenic sources (leaded gasoline and industrial lead from Rio Tinto ore). - Highlights: • Urban speleothems from underground aqueduct in Paris, France were

Three centuries of heavy metal pollution in Paris (France) recorded by urban speleothems

International Nuclear Information System (INIS)

Pons-Branchu, Edwige; Ayrault, Sophie; Roy-Barman, Matthieu; Bordier, Louise; Borst, Wolfgang; Branchu, Philippe; Douville, Eric; Dumont, Emmanuel

2015-01-01

The first record of urban speleothems used to reconstruct the history of heavy metal pollution of shallow groundwaters is presented. Two speleothems grew during the last 300 years in an underground aqueduct in the north-eastern part of Paris. They display high Pb, Mn V, Cu, Cd and Al concentrations since 1900 due to the urbanization of the site which triggered anthropogenic contamination of the water feeding the speleothems. Surprisingly, these heavy metal concentrations are also high in the oldest part. This early pollution could come from the use of Parisian waste as fertilizers in the orchards and vineyards cultivated above the aqueduct before urbanization. Lead isotopes were measured in these carbonates as well as in lead artifacts from the 17th–18th centuries ( 206 Pb/ 207 Pb = 1.180 +/− 0.003). The mean 206 Pb/ 207 Pb ratio, for one of the speleothems is 1.181 +/− 0.003 unvarying with time. These lead signatures are close to those of coal and old lead from northern European mines, lower than the natural background signature. It confirms that the high metal concentrations found come from anthropogenic pollution. Conversely, the lead isotopic composition of the second speleothem presents two temporal trends: for the oldest levels, the mean value (1.183 +/− 0.003) is similar to the first speleothem. For the youngest part, a lower value (1.172 +/− 0.005) is recorded, evidencing the contribution of a new lead source at the beginning of the industrial revolution. Pb isotopes were also measured in recent samples from a nearby superficial site. The first sample is a recent (AD 1975 +/− 15 years) deposit ( 206 Pb/ 207 Pb = 1.148 +/− 0.003), and the second, a thin subactual layer ( 206 Pb/ 207 Pb = 1.181 +/− 0.002). These data are compatible with the adding of anthropogenic sources (leaded gasoline and industrial lead from Rio Tinto ore). - Highlights: • Urban speleothems from underground aqueduct in Paris, France were studied. • Speleothems are

Urbanization impact on sulfur content of groundwater revealed by the study of urban speleothem-like deposits: Case study in Paris, France.

Science.gov (United States)

Pons-Branchu, E; Roy-Barman, M; Jean-Soro, L; Guillerme, A; Branchu, P; Fernandez, M; Dumont, E; Douville, E; Michelot, J L; Phillips, A M

2017-02-01

Speleothem-like deposits that develop underground in urban areas are an archive of the environmental impact of anthropic activities that has been little studied so far. In this paper, the sulfate content in shallow groundwater from northern Paris (France) is compared with the sulfur content in two 300-year-old urban carbonate deposits that grew in a historical underground aqueduct. The present-day waters of the aqueduct have very high sulfur and calcium contents, suggesting pollution from gypsum dissolution. However, geological gypsum levels are located below the water table. Sulfur content was measured by micro-X-ray fluorescence in these very S-rich carbonate deposits (0.5 to 1% of S). A twofold S increase during the second half of the 1800s was found in both samples. These dates correspond to two major periods of urbanization above the site. We discus three possible S sources: anthropic sources (industries, fertilizers…), volcanic eruptions and input within the water through gypsum brought for urbanization above the studied site (backfill with quarry waste) since the middle of the 19th century. For the younger second half of the studied section, S input from gypsum brought during urbanization was confirmed by the study of isotopic sulfur composition (δ 34 S=+15.2‰ at the top). For the oldest part, several sulfur peaks could be related to early industrial activity in Paris, that caused high local air pollution, as reported in historical archives but also to historical gypsum extraction. This study provides information on the origin and timing of the very high SO 4 2- levels measured nowadays within the shallow groundwater, thus demonstrating the interest in using carbonate deposits in urban areas as a proxy for the history of urbanization or human activities and their impact on water bodies. Copyright © 2016 Elsevier B.V. All rights reserved.

The Paris Agreement to Ignore Reality

OpenAIRE

Spash, Clive L.

2016-01-01

At the 21st session of the Conference of the Parties to the United Nations Framework Convention on Climate Change held in Paris, France, 30 November to 11 December 2015, an Agreement was reached by the international community including 195 countries. The Agreement has been hailed, by participants and the media, as a major turning point for policy in the struggle to address human induced climate change. The following is a short critical commentary in which I briefly explain why ...

Atypical aetiology of a conjugal fever: autochthonous airport malaria between Paris and French Riviera: a case report

Directory of Open Access Journals (Sweden)

Fontenille Didier

2009-08-01

Full Text Available Abstract Endemic malaria has been eradicated from France, but some falciparum malaria cases have been described in patients who have never travelled outside the country. Ms. V. 21 year-old and Mr. M. 23 year-old living together in Paris were on holiday in Saint Raphaël (French Riviera. They presented with fever, vertigo and nausea. A blood smear made to control thrombocytopaenia revealed intra-erythrocytic forms of Plasmodium falciparum. The parasitaemia level was 0.15% for Ms. V and 3.2% for Mr. M. This couple had no history of blood transfusion or intravenous drug use. They had never travelled outside metropolitan France, but had recently travelled around France: to Saint Mard (close to Paris Charles de Gaulle (CdG airport, to Barneville plage (in Normandy and finally to Saint Raphaël. The most probable hypothesis is an infection transmitted in Saint Mard by an imported anopheline mosquito at CdG airport. The DNA analysis of parasites from Ms. V.'s and Mr. M.'s blood revealed identical genotypes. Because it is unlikely that two different anopheline mosquitoes would be infected by exactly the same clones, the two infections must have been caused by the infective bites of the same infected mosquito.

Paris

Science.gov (United States)

2001-01-01

[figure removed for brevity, see original site] Figure 1 This image of Paris was acquired on July 23, 2000 and covers an area of 23 by 20 km. Known as the City of Light, Paris has been extolled for centuries as one of the great cities of the world. Its location on the Seine River, at a strategic crossroads of land and river routes, has been the key to its expansion since the Parisii tribe first settled here in the 3rd century BC. Paris is an alluring city boasting many monumental landmarks, such as the Cathedral of Notre Dame, the Louvre, and the Eiffel Tower. Its beautiful gardens, world-class cuisine, high fashion, sidewalk cafes, and intellectual endeavors are well known. The city's cultural life is centered on the Left Bank of the Seine, while business and commerce dominate the Right Bank. The image is located at 48.8 degrees north latitude and 2.3 degrees east longitude. In figure 1, the 4 enlarged areas zoom in to some of the major buildings. In the UPPER LEFT, the Eiffel Tower and its shadow are seen. Based on the length of the shadow and the solar elevation angle of 59 degrees, we can calculate its height as 324 m (1054 ft), compared to its actual height of 303 m (985 ft). In the UPPER RIGHT, the Arc de Triomphe is at the center of the Place de L'etoile, from which radiate 12 major boulevards. In the LOWER LEFT is the Tuileries Garden and the Louvre Museum art its eastern end. In the LOWER RIGHT is the Invalides, the burial place and monument of Napoleon Bonaparte. The U.S. science team is located at NASA's Jet Propulsion Laboratory, Pasadena, Calif. The Terra mission is part of NASA's Science Mission Directorate.

European and Americas Committees for Treatment and Research in Multiple Sclerosis (ECTRIMS/ACTRIMS) - 7th Joint Triennial Congress (October 25-28, 2017 - Paris, France).

Science.gov (United States)

Díaz, N

2017-10-01

The 7th Triennial Joint conference of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) and Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) was held in Paris, France. The meeting brought together attendees from a wide range of disciplines involved in multiple sclerosis (MS) research to explore an extensive program of teaching courses, plenary lectures, oral and poster sessions from approximately 2,000 abstracts submitted, and hot topic and young investigator presentations. These presentations covered topics including diagnostics, therapeutics and biomarkers, as well as a special section for MS nurses. Industry-sponsored symposia were also held. The report from this conference covers the latest developments in MS treatments.

Smoke Inhalation and Cyanide Poisoning: 20 Years of Paris Experience

International Nuclear Information System (INIS)

Baud, F. J.

2007-01-01

Hydroxocobalamin has been used as a cyanide poisoning antidote for many years in France. It has recently been approved by the US FDA. In Paris, hydroxocobalamin is carried by the Brigade de Sapeurs Pompiers (Paris Fire Brigade) in mobile intensive care vehicles and has been administered empirically to victims of enclosed-space fire smoke inhalation who meet the criteria of having soot in the nose, mouth, or throat, any alteration in mental status or disturbance in consciousness, and especially if any degree of hypotension is present (BP less than or equal to 100 mmHg systolic). The administration of hydroxocobalamin at the scene was shown to be safe. Hydroxocobalamin has also been efficacious and safe in 'pure' cyanide poisoning, as long as brain death has not already occurred. A 'toxidrome' of cyanide poisoning has been developed in our institution in Paris, and its application can assist in making the diagnosis of this life-threatening poisoning which cannot be emergent diagnosed by currently-available laboratory methods.(author)

The pioneers of radioactivity. From the Museum to the College de France

International Nuclear Information System (INIS)

1998-01-01

This educative guidebook is built like a touristic itinerary threw Paris (France) which follows the footpaths of the French pioneers of radioactivity from the Museum, dominated by the 'Becquerel dynasty', to the College de France. This scientific route is a good way to familiarize oneself with science and its actors. (J.S.)

2006 annual results: Gaz de France announces record-high results and exceeds its objectives

International Nuclear Information System (INIS)

2007-01-01

Paris, 13 March 2007 - In fiscal year 2006, Gaz de France had the best operational performance in its history. The Group confirms the strength of its business model, with sound Infrastructure business and sharp growth in Exploration - Production, Trading and Sales: - Net income, Group share: 2.3 billion euros; - EBITDA: 5.15 billion euros; - Dynamic dividend policy: 1.1 euro per share (+62%); - Investments at stepped-up pace: 4 billion euros (+38%); - Contribution of Group's international activities doubled in two years (39% of sales); - Many operational advances: strengthened operations, Exploration-Production, LNG Infrastructures and Electricity; - Major steps completed in merger project with Suez

The impact of area residential property values on self-rated health: A cross-sectional comparative study of Seattle and Paris

Directory of Open Access Journals (Sweden)

Junfeng Jiao

2016-12-01

Full Text Available This study analyzed the impact of area residential property values, an objective measure of socioeconomic status (SES, on self-rated health (SRH in Seattle, Washington and Paris, France. This study brings forth a valuable comparison of SRH between cities that have contrasting urban forms, population compositions, residential segregation, food systems and transportation modes. The SOS (Seattle Obesity Study was based on a representative sample of 1394 adult residents of Seattle and King County in the United States. The RECORD Study (Residential Environment and Coronary Heart Disease was based on 7131 adult residents of Paris and its suburbs in France. Socio-demographics, SRH and body weights were obtained from telephone surveys (SOS and in-person interviews (RECORD. All home addresses were geocoded using ArcGIS 9.3.1 (ESRI, Redlands, CA. Residential property values were obtained from tax records (Seattle and from real estate sales (Paris. Binary logistic regression models were used to test the associations among demographic and SES variables and SRH. Higher area property values significantly associated with better SRH, adjusting for age, gender, individual education, incomes, and BMI. The associations were significant for both cities. A one-unit increase in body mass index (BMI was more detrimental to SRH in Seattle than in Paris. In both cities, higher area residential property values were related to a significantly lower obesity risk and better SRH. Ranked residential property values can be useful for health and weight studies, including those involving social inequalities and cross-country comparisons.

[History of the Journées Dermatologiques de Paris].

Science.gov (United States)

Tilles, G

2013-12-01

Founded in 1801 at the Hôpital Saint-Louis, Paris, under Jean-Louis Alibert, the French School of Dermatology was initially structured around the French Society of Dermatology (1889) and the organization of two world congresses (Paris 1889, 1900). After World War I, the creation of dermatological societies in the provinces infused French dermatology with new energy. In 1922, the first congress of the French-speaking dermatologists further contributed to the public profile of dermatologists in France. The "Journées de Mars" were initiated in 1961 at the Hôpital Saint-Louis, and in 1975 they went on to become the "Journées dermatologiques de Paris". Pr. Jean Civatte played a key role in their creation and in their organization for 30 years. After 1979, since actual patients could no longer be presented, the organizers of the congress had to change the content of the meeting from clinical presentations to post-graduate teaching and clinical research. From its origins in the form of meetings of French dermatologists in an intimate setting at the Hôpital Saint-Louis, the "Journées dermatologiques de Paris" grew within the ensuing decades into a major scientific event of the French-speaking dermatological community, bringing together more than 4000 participants in December each year. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

3-D basin modelling of the Paris Basin: diagenetic and hydrogeologic implications

International Nuclear Information System (INIS)

Violette, S.; Goncalves, J.; Jost, A.; Marsily, G. de

2004-01-01

A 3-D basin model of the Paris basin is presented in order to simulate through geological times fluid, heat and solute fluxes. This study emphasizes: i) the contribution of basin models to the quantitative hydrodynamic understanding of behaviour of the basin over geological times; ii) the additional use of Atmospheric General Circulation model (AGCM) to provide palaeo-climatic boundaries for a coupled flow and mass transfer modelling, constrained by geochemical and isotopic tracers and; iii) the integration of different types of data (qualitative and quantitative) to better constrain the simulations. Firstly, in a genetic way, basin model is used to reproduce geological, physical and chemical processes occurring in the course of the 248 My evolution of the Paris basin that ought to explain the present-day hydraulic properties at the regional scale. As basin codes try to reproduce some of these phenomena, they should be able to give a plausible idea of the regional-scale permeability distribution of the multi-layered system, of the pre-industrial hydrodynamic conditions within the aquifers and of the diagenesis timing and type of hydrodynamic processes involved. Secondly, climate records archived in the Paris basin groundwater suggest that climate and morphological features have an impact on the hydrogeological processes, particularly during the last 5 My. An Atmospheric General Circulation model is used with a refined spatial resolution centred on the Paris basin to reproduce the climate for the present, the Last Glacial Maximum (21 ky) and the middle Pliocene (3 My). These climates will be prescribed, through forcing functions to the hydrological code with the main objective of understanding the way aquifers and aquitards react under different climate conditions, the period and the duration of these effects. Finally, the Paris basin has been studied for a number of years by different scientific communities, thus a large amount of data has been collected. By

Where are the radioactive wastes in France? Brochure no 1; Ou sont les dechets radioactifs en France? Brochure no 1

Energy Technology Data Exchange (ETDEWEB)

NONE

2004-07-01

This document is one of the 6 regional brochures which make the geographical inventory of radioactive wastes in France. For each region, a table lists the recorded sites and a regional map localizes those having a detailed descriptive file. These files mention the most important waste owners (medical, research, nuclear and military industries), the type of waste and the type of management. The polluted sites are also mentioned, even if they are already decontaminated. The volume no 1 concerns the Ile-de-France region (Paris region). (J.S.)

2006 annual results: Gaz de France announces record-high results and exceeds its objectives

Energy Technology Data Exchange (ETDEWEB)

NONE

2007-07-01

Paris, 13 March 2007 - In fiscal year 2006, Gaz de France had the best operational performance in its history. The Group confirms the strength of its business model, with sound Infrastructure business and sharp growth in Exploration - Production, Trading and Sales: - Net income, Group share: 2.3 billion euros; - EBITDA: 5.15 billion euros; - Dynamic dividend policy: 1.1 euro per share (+62%); - Investments at stepped-up pace: 4 billion euros (+38%); - Contribution of Group's international activities doubled in two years (39% of sales); - Many operational advances: strengthened operations, Exploration-Production, LNG Infrastructures and Electricity; - Major steps completed in merger project with Suez.

Variability of air ion concentrations in urban Paris

Science.gov (United States)

Dos Santos, V. N.; Herrmann, E.; Manninen, H. E.; Hussein, T.; Hakala, J.; Nieminen, T.; Aalto, P. P.; Merkel, M.; Wiedensohler, A.; Kulmala, M.; Petäjä, T.; Hämeri, K.

2015-12-01

Air ion concentrations influence new particle formation and consequently the global aerosol as potential cloud condensation nuclei. We aimed to evaluate air ion concentrations and characteristics of new particle formation events (NPF) in the megacity of Paris, France, within the MEGAPOLI (Megacities: Emissions, urban, regional and Global Atmospheric Pollution and climate effects, and Integrated tools for assessment and mitigation) project. We measured air ion number size distributions (0.8-42 nm) with an air ion spectrometer and fine particle number concentrations (> 6 nm) with a twin differential mobility particle sizer in an urban site of Paris between 26 June 2009 and 4 October 2010. Air ions were size classified as small (0.8-2 nm), intermediate (2-7 nm), and large (7-20 nm). The median concentrations of small and large ions were 670 and 680 cm-3, respectively, (sum of positive and negative polarities), whereas the median concentration of intermediate ions was only 20 cm-3, as these ions were mostly present during new particle formation bursts, i.e. when gas-to-particle conversion produced fresh aerosol particles from gas phase precursors. During peaks in traffic-related particle number, the concentrations of small and intermediate ions decreased, whereas the concentrations of large ions increased. Seasonal variations affected the ion population differently, with respect to their size and polarity. NPF was observed in 13 % of the days, being most frequent in spring and late summer (April, May, July, and August). The results also suggest that NPF was favoured on the weekends in comparison to workdays, likely due to the lower levels of condensation sinks in the mornings of weekends (CS weekdays 09:00: 18 × 10-3 s-1; CS weekend 09:00: 8 × 10-3 s-1). The median growth rates (GR) of ions during the NPF events varied between 3 and 7 nm h-1, increasing with the ion size and being higher on workdays than on weekends for intermediate and large ions. The median GR of

Highlights from the WIN 2017 Symposium, 26-27 June 2017, Paris, France: 'Expediting Global Innovation in Precision Cancer Medicine'.

Science.gov (United States)

Davies, Will

2017-01-01

The Worldwide Innovative Networking (WIN) symposium brings together representatives from academic institutions, pharmaceutical partners, technology companies and charitable organisations from across the globe for an annual summit, discussing ongoing research and the latest developments in precision medicine. Now, in its seventh year, the aims of the WIN consortium's annual meeting, to foster communication and collaboration between members and deliver clinical trial results that improve the care and outcomes of patients are presented in open dialogue to encourage debate and discussion. This year, the meeting was held in Paris, France from 26-27 June and consisted of six plenary sessions, two debates, and poster presentations from attendees. In keeping with the consortium's goals, presentations and posters focused on the development and integration of new therapies and updates in genome-based medicine. Among the presentations at this year's meeting, much of the focus fell on design and implementation of new designs of clinical trials, moving away from decades-long assessments of thousands of patients towards a nimble, adaptive design fitting the edicts of personalised medicine and delving into greater depths within genomic data, ranging beyond genome analysis to chart new targets in ligandomics, proteogenomics and more.

Report of visiting Laboratoire de Physique des Gaz et des Plasmas, Universite Paris-Sud

International Nuclear Information System (INIS)

Ferreira, J.L.

1991-03-01

The activities carried out by identification mission to the Laboratoire de Physique des Gaz et des Plasmas (LPGP) of Paris-Sud University are related. The mission is part of the project of Study on Plasma wave and Plasma turbulence which is part of international agreement between CAPES and COFECUB in France. (M.C.K.)

GHG monitoring over Paris megacity and Orléans forest

Science.gov (United States)

Te, Y. V.; Jeseck, P.; Zanon, T.; Boursier, C.; Janssen, C.; Deutscher, N. M.; Warneke, T.; Notholt, J.; Lac, C.; Dieudonné, E.; Lopez, M.; Schmidt, M.; Xueref-remy, I. C.

2012-12-01

In a growing world with more than 7 billion inhabitants and big emerging countries such as China, Brazil and India, emissions of anthropogenic pollutants and greenhouse gases (GHGs) are increasing continuously. Their monitoring and control in megacities have become a major challenge for scientists and public health authorities in environmental research area. The ground-based Fourier transform spectrometer (QualAir FTS[a], model IFS 125HR) of the QualAir platform located in downtown Paris at University Pierre et Marie Curie (UPMC), is a scientific research instrument dedicated to the survey of greenhouse gases (GHGs) and urban air quality. Equipped with a sun-tracker, the remote sensing QualAir FTS relies on solar infrared absorption for monitoring trace gas concentrations and their variability in the Ile-de-France region[b]. Concentrations of atmospheric GHGs, especially CO2, CH4 and N2O, are retrieved by the radiative transfer model PROFFIT[c]. Because Paris is the third largest European megacity, the QualAir FTS can provide new and complementary measurements as compared to existing ground-based FTS network stations (NDACC and TCCON) located in unpolluted environments, such as the TCCON-Orléans station[d] situated in the forest of Orléans (100 km south of Paris). In the effort to integrate QualAir FTS into the TCCON network, simultaneous FTS measurements of GHGs at Paris and Orléans have been performed. We will emphasize on comparisons of CO2 from these two sites. Our comparison will be completed by high-resolved direct CO2 modeling outputs from the Meso-NH model, and ground in situ measurements at different sites (Orléans/Trainou, Paris/Jussieu, Paris/Eiffel Tower). Parts of the data were acquired in the framework of the French CO2-MEGAPARIS project[e, f], whose main goal is to quantify CO2 emissions from the Paris area. The present data intercomparison will help to reduce uncertainties in carbon cycle models and to better characterize regional GHG fluxes

Acts of terrorism in Paris and Brussels: common and different

Directory of Open Access Journals (Sweden)

O. S. Vonsovych

2016-10-01

Full Text Available The article investigates the common and distinctive features of the terrorist attacks in Paris and Brussels in 2015 and 2016. The attacks have confirmed the weakness of European security system in the context of the protection of its citizens from the threat № 1 in the world. The high level of democracy and liberalism are not allowed to use power instruments effectively in the fight against terrorism, which was the result of the fact that the terrorists were able to freely access to the place of their acts and to implement them. It was determined that the common features are the following: in Paris and in Brussels, the attacks were carried out by terrorist militaristic group «The Islamic State of Iraq and the Levant» (ISIL; the places of commission of terrorist acts; guns of terrorists; military units of France and Belgium are parties of the armed conflict in Syria on the side of the Syrian opposition and struggle against ISIL; there were a few terrorist attacks. It is proved that the differences are as follows: in Paris, in addition to explosives, packed with nails, also were used automatic weapons and grenades, but only explosives in Brussels; France is more active in the fight against terrorism in the international arena and in every way opposed to violence against humanity, so there is a terrorist attack can be seen as a blow to the democratic and humanitarian values; Belgium is a «political heart» of the European Union that’s why the terrorist attack on it can be seen as a blow to the political system of the EU; in Paris, the attack was supposed to apply except for the population and for high officials in the name of F. Hollande and F. Steinmeier, and in Brussels – only civilians.conducting effective public diplomacy by means of virtual diplomacy. In the context of the establishment of the global information society the key target groups must be: Diasporas, foreign media (including bloggers, investors, influential foreign

Gaz de France: first half 2007 results

Energy Technology Data Exchange (ETDEWEB)

NONE

2007-07-01

Paris, 29 August 2007, Gaz de France Group presents its first half 2007 results (billion euros): Sales revenue 13.78 (-11% with respect to 2006), EBITDA 3.11 (-4.9%), Operating income 2.33 ( -8.7%), Net income Group share 1.51 (-11%), Net income Group share per share 1.53 euro (-11%). The half-year results are attributable primarily to three factors: - A very difficult environment with exceptionally mild climate conditions in the first half, impacting nearly all of the businesses, and unfavourable market conditions, reflected in particular in the low gas prices on the markets; - A tariff context which did not negatively impact the sales margins following a very difficult year 2006; - Good performance in international activities. Despite the environment, the Group is maintaining its financial target for 2007, as announced in March this year: 2007 will be a year of consolidation. EBITDA is expected to be in line with that of 2006. This target assumes average climate conditions during the second half 2007.

Gaz de France: first half 2007 results

International Nuclear Information System (INIS)

2007-01-01

Paris, 29 August 2007, Gaz de France Group presents its first half 2007 results (billion euros): Sales revenue 13.78 (-11% with respect to 2006), EBITDA 3.11 (-4.9%), Operating income 2.33 ( -8.7%), Net income Group share 1.51 (-11%), Net income Group share per share 1.53 euro (-11%). The half-year results are attributable primarily to three factors: - A very difficult environment with exceptionally mild climate conditions in the first half, impacting nearly all of the businesses, and unfavourable market conditions, reflected in particular in the low gas prices on the markets; - A tariff context which did not negatively impact the sales margins following a very difficult year 2006; - Good performance in international activities. Despite the environment, the Group is maintaining its financial target for 2007, as announced in March this year: 2007 will be a year of consolidation. EBITDA is expected to be in line with that of 2006. This target assumes average climate conditions during the second half 2007

Hydrothermal alteration studies of gabbros from northern central Indian ridge and their geodynamic implications

Digital Repository Service at National Institute of Oceanography (India)

Ray, Dwijesh; Mevel, C.; Banerjee, R.

, IPGP, 4 Place Jussieu, F-75252 Paris Cedex 5, France. 3 National Institute of Oceanography, Goa 403 004, India. ∗ e-mail: dwijesh@rediffmail.com Mylonitic gabbro and altered gabbro were recovered from off-axis high and corner high loca- tions at ridge... microprobe analyzer at the CAMPARIS service of the IPG-Paris (University of Paris 6, France). Analytical conditions used were 15 kV accelerating voltage, 20 nA beam current and 20–40 s count- ing times. All analyses were performed in a point mode. A 2–3 µm...

The COCCON Paris Experiment - Model-Data Comparison of XCO2 (and XCH4) in an Urban Environment

Science.gov (United States)

Vogel, F. R.; Staufer, J.; Frey, M.; Broquet, G.; Xueref-Remy, I.; Sha, M. K.; Blumenstock, T.; Te, Y. V.; Janssen, C.; Jeseck, P.; Chelin, P.; Fratacci, T.; Tu, Q.; Gross, J.; Schäfer, K.; Orphal, J.; Ciais, P.; Hase, F.

2016-12-01

Currently, over 50% of the global population lives in urban areas1 and the future population growth is also predicted to occur mostly in urban centers. While emissions of Greenhouse Gases and carbon-based air pollutants can be estimated quite precisely on national scale using fuel consumption statistics, typically to about 3%-40%2, higher uncertainties of 20%-50% are reported3 for urban GHG emissions. Atmospheric observations, when combined with inversion modelling can allow independently assessing such urban emission inventories4. This study investigates how well novel low-resolution FTS observations can be represented within atmospheric transport models used in such inversion systems, which would be the pre-requisite for a future system based on XCO2 observations. A network of five EM27sun instruments5,6was deployed across the Paris Metropolitan region (upwind, downwind and inside of Paris, diameter ca. 40km) for a three week period in spring 2015. Observed XCO2 significantly varies during this period ranging from 400.5ppm to 406ppm. A decrease in XCO2 throughout the day, likely driven by the biogenic CO2 uptake in the region, is recorded at all sites. Both observational and simulated XCO2 also clearly show that the emissions in the Paris region significantly increase XCO2 (0-2ppm), depending on meteorological conditions. The observational data is compared to three configurations of our XCO2 forward model to assess their performance. We find that all simulations and observations agree qualitatively and that the gradient of XCO2 over Paris can also be reproduced quantitatively for specific meteorological conditions and optimal model setup. 1United Nations, Department of Economic and Social Affairs, Population Division (2014). World Urbanization Prospects: The 2014 Revision 2Anders et al. 2014, Tellus B 2014, 66, 23616, http://dx.doi.org/10.3402/tellusb.v66.23616 3Wu et al. 2016, Atmos. Chem. Phys., 16, 7743-7771, doi:10.5194/acp-16-7743-2016 4Staufer et al. 2016

NOGENT, just another power plant - but so close to Paris

International Nuclear Information System (INIS)

Fournel, Brigitte

1993-01-01

54 PWR type production units are today operating in France. Between 1980 and 1981, 11 units were under construction including both Nogent PWR-1300 units. The increasing consumption in the lie de France region in the early eighties affected the choice of the site so close to Paris on the banks of the Seine, not more than 95 km from Notre Dame Cathedral. In February 1975, the Champagne-Ardenne Regional Council gave a favourable opinion to installation of a nuclear power plant in the Marne or Seine valley. The location of the plant thus offered an economic opportunity to a region in which second homes were growing at the expense of primary residences. The Nogent plant is not the only one to be situated close to a city. One of the major concerns was related to the fact that the power plant was located on the banks of the river supplying Paris with drinking water. The plant has a geographical location whose political and media implications are Parisian, and thus national. Therefore, the plant was equipped with a public information centre which opened on 1st January 1988, and which in general receives some 20 000 visitors annually. It is located outside the controlled areas of the plant and access is free to all visitors. It gives a permanent exhibition on nuclear power and the Nogent plant in particular. Its auditorium can seat 120 for conferences and films on all subjects concerning nuclear power. The construction of the Information Centre cost 6 million francs. The visitors mainly come from the Paris region : many teachers bring their classes to find out about our installations. The EDF Divisions bring many notable visitors : foreign ministers, captains of industry, and any foreign nuclear company on an information visit to France. The opposition to Nogent comes mainly from Paris, in 1979 of a Committee for nuclear alternatives called Stop-Nogent was established. 1982,1983,1984 and 1985 were marked by strong action and local disputes, reported in the press (sabotage

NOGENT, just another power plant - but so close to Paris

Energy Technology Data Exchange (ETDEWEB)

Fournel, Brigitte [Electricite de France (France)

1993-07-01

54 PWR type production units are today operating in France. Between 1980 and 1981, 11 units were under construction including both Nogent PWR-1300 units. The increasing consumption in the lie de France region in the early eighties affected the choice of the site so close to Paris on the banks of the Seine, not more than 95 km from Notre Dame Cathedral. In February 1975, the Champagne-Ardenne Regional Council gave a favourable opinion to installation of a nuclear power plant in the Marne or Seine valley. The location of the plant thus offered an economic opportunity to a region in which second homes were growing at the expense of primary residences. The Nogent plant is not the only one to be situated close to a city. One of the major concerns was related to the fact that the power plant was located on the banks of the river supplying Paris with drinking water. The plant has a geographical location whose political and media implications are Parisian, and thus national. Therefore, the plant was equipped with a public information centre which opened on 1st January 1988, and which in general receives some 20 000 visitors annually. It is located outside the controlled areas of the plant and access is free to all visitors. It gives a permanent exhibition on nuclear power and the Nogent plant in particular. Its auditorium can seat 120 for conferences and films on all subjects concerning nuclear power. The construction of the Information Centre cost 6 million francs. The visitors mainly come from the Paris region : many teachers bring their classes to find out about our installations. The EDF Divisions bring many notable visitors : foreign ministers, captains of industry, and any foreign nuclear company on an information visit to France. The opposition to Nogent comes mainly from Paris, in 1979 of a Committee for nuclear alternatives called Stop-Nogent was established. 1982,1983,1984 and 1985 were marked by strong action and local disputes, reported in the press (sabotage

Where are the radioactive wastes in France? Brochure no 1

International Nuclear Information System (INIS)

2004-01-01

This document is one of the 6 regional brochures which make the geographical inventory of radioactive wastes in France. For each region, a table lists the recorded sites and a regional map localizes those having a detailed descriptive file. These files mention the most important waste owners (medical, research, nuclear and military industries), the type of waste and the type of management. The polluted sites are also mentioned, even if they are already decontaminated. The volume no 1 concerns the Ile-de-France region (Paris region). (J.S.)

New Introductions of Enterovirus 71 Subgenogroup C4 Strains, France, 2012

Science.gov (United States)

Henquell, Cécile; Mirand, Audrey; Coste-Burel, Marianne; Marque-Juillet, Stéphanie; Desbois, Delphine; Lagathu, Gisèle; Bornebusch, Laure; Bailly, Jean-Luc; Lina, Bruno

2014-01-01

In France during 2012, human enterovirus 71 (EV-A71) subgenogroup C4 strains were detected in 4 children hospitalized for neonatal fever or meningitis. Phylogenetic analysis showed novel and independent EV-A71 introductions, presumably from China, and suggested circulation of C4 strains throughout France. This observation emphasizes the need for monitoring EV-A71 infections in Europe. PMID:25061698

New introductions of enterovirus 71 subgenogroup C4 strains, France, 2012.

Science.gov (United States)

Schuffenecker, Isabelle; Henquell, Cécile; Mirand, Audrey; Coste-Burel, Marianne; Marque-Juillet, Stéphanie; Desbois, Delphine; Lagathu, Gisèle; Bornebusch, Laure; Bailly, Jean-Luc; Lina, Bruno

2014-08-01

In France during 2012, human enterovirus 71 (EV-A71) subgenogroup C4 strains were detected in 4 children hospitalized for neonatal fever or meningitis. Phylogenetic analysis showed novel and independent EV-A71 introductions, presumably from China, and suggested circulation of C4 strains throughout France. This observation emphasizes the need for monitoring EV-A71 infections in Europe.

Men from Sub-Saharan Africa Living in Worker Hostels in France: A Hidden Population with Poor Access to HIV Testing.

Science.gov (United States)

Guiguet, M; Dionou, S; Volant, J; Samba, M C; Benammar, N; Chauvin, P; Simon, A

2017-08-01

Delayed presentation to care among HIV-infected individuals continued to be frequent in France. Migrants are at high risk for late presentation. This cross-sectional study investigated barriers to HIV testing in the specific population of men from sub-Saharan Africa living in four migrant worker hostels in Paris, France. Factors associated with never having been tested for HIV were examined using logistic regression. In all, 550 men participated, coming mainly from Mali and Senegal, with 31 % having lived in France for less than 5 years, and 25 % without any health insurance. Only 37 % have ever been tested for HIV. Not having health insurance was the main risk factor for never-testing [adjusted odds ratio (aOR) 2.4; 95 % confidence interval (CI) 1.4-4.0]. Despite free and anonymous HIV testing available at dedicated public screening centers, 63 % of men living in migrant worker hostels had never been tested for HIV.

ClimasCOPe: Exploring the challenges behind the Paris Agreement - COP21

International Nuclear Information System (INIS)

Leguet, Benoit; Alberola, Emilie; Afriat, Marion; Vaidyula, Manasvini; Morel, Romain; Cochran, Ian; Deheza, Mariana; Shishlov, Igor; Leseur, Alexia; Depoues, Vivian; Bordier, Cecile; Bultheel, Clement; Bellassen, Valentin

2015-04-01

In the framework of the 21. Conference of the Parties (COP21) to the United Nations Framework Convention on Climate Change (UNFCCC), held in Paris from November 30 to December 11 2015, I4CE - Institute for Climate Economics, in partnership with ADEME, the French Environment and Energy Management Agency, attempts to shed some light on the challenges surrounding this Paris Climate Conference 2015. They explore what can be expected from the post-2020 climate agreement in Paris. They also discuss some keys success indicators of such an agreement. Over the course of six issues, ClimasCOPe provides analysis related to carbon pricing, climate finance, greenhouse gas (GHG) emissions' accounting, the role of sub-national actors, adaptation to climate change and the compatibility of government commitments with the scenario where in global mean temperatures would rise by no more than 2 deg. C. Issue 1 - Carbon pricing: a necessary tool on the agenda of solutions for climate funding (Putting a Price on Carbon, First submissions of intended Nationally Determined Contributions for Paris Agreement, 5 carbon pricing initiatives); Issue 2 - Financing the low-carbon transition: the need for coherence between regulations and ambition (Finance will be the cornerstone of the Paris accord, News, 5 initiatives for Climate Finance); Issue 3 - Three keys to effective GHG emissions monitoring for a broader climate agreement (MRV: how to hit the bull's eye when there is no silver bullet? First Climate Week and the Bonn negotiations, 3 MRV initiatives); Issue 4 - Non-state actors: pushing the climate action agenda forward (The role of cities and regions and their knock-on effects, G7 announcements and the process of adopting the SDGs, 4 non-state actor initiatives); Issue 5 - COP 21: a new approach and the launch of a process to address climate change adaptation (Adapting to climate change: taking ownership of the issues and removing barriers to implementation, First COP 21 draft

Key figures on climate France, Europe and Worldwide. Edition 2018

International Nuclear Information System (INIS)

Baude, Manuel; Dussud, Francois-Xavier; Ecoiffier, Mathieu; Moreau, Sylvain; Bottin, Anne; Duvernoy, Jerome; Vailles, Charlotte

2017-10-01

In line with previous years, the 2018 edition of 'Key figures on climate' has been written in the context of the 22. Conference of the Parties on Climate Change (COP 22) held in Bonn from 6 to 17 November 2017. This latest version was updated relative to the 2017 edition. New data sources have been used for emissions factors and the part on the carbon footprint was further developed. The part on climate policies notably deals with the Paris Agreement adopted in December 2015 at COP 21. Several data sets, displayed in graphs in this document are also available in tables on the web version. Content: 1 - What is climate change? This part summarizes the scientific basis of climate change, including indicators, causes and possible consequences of global warming. 2 - Which amounts of greenhouse gases are emitted globally? The focus here is on the most relevant data related to global greenhouse gases (GHG) emissions, in particular the geographic distribution of these emissions. 3 - How much greenhouse gas is emitted in Europe and in France? A complete overview of GHG emissions statistics in Europe and in France is presented in this part as well as estimates of the carbon footprint of French people. 4 - What is the sectoral distribution of GHG emissions in Europe and in France? This part features the detailed evolution since 1990 of GHG emissions in the following economic sectors: energy sector, transports, industry, residential and tertiary, agriculture, forestry, land use and waste management. 5 - Which climate policies in the world, in Europe and in France? The main climate policies are described at each level: global, European and French

Paris saponin-induced autophagy promotes breast cancer cell apoptosis via the Akt/mTOR signaling pathway.

Science.gov (United States)

Xie, Zhan-Zhi; Li, Man-Mei; Deng, Peng-Fei; Wang, Sheng; Wang, Lei; Lu, Xue-Ping; Hu, Liu-Bing; Chen, Zui; Jie, Hui-Yang; Wang, Yi-Fei; Liu, Xiao-Xiao; Liu, Zhong

2017-02-25

Paris saponins possess anticancer, anti-inflammatory, and antiviral effects. However, the anticancer effect of Paris saponins has not been well elucidated and the mechanisms underlying the potential function of Paris saponins in cancer therapy are needed to be further identify. In this study, we report that saponin compounds isolated from Paris polyphylla exhibited antitumor activity against breast cancer cell lines, MCF-7 and MDA-MB-231. Paris saponin XA-2 induced apoptosis in both cell lines, as evidenced by the activation of caspases and cleavage of Poly (ADP-ribose) polymerase. The ability of XA-2 to induce autophagy was confirmed by acridine orange staining, accumulation of autophagosome-bound Long chain 3 (LC3)-II, and measurement of autophagic flux. XA-2-induced autophagy was observed to promote apoptosis by the combined treatment of breast cancer cell lines with XA-2 and autophagy inhibitors 3-methyladenine and bafilomycin A1, respectively. Moreover, we report a decrease in the levels of Akt/mTOR signaling pathway proteins, such as the phosphorylated forms of Akt, mTOR, P70S6K, and eukaryotic translation initiation factor 4E-binding protein 1 (4EBP1). Taken together, these results provide important insights explaining the anticancer activity of Paris saponins and the potential development of XA-2 as a new therapeutic agent. Copyright © 2017 Elsevier B.V. All rights reserved.

VizieR Online Data Catalog: The Canada-France Redshift Survey (CFRS) (Lilly+, 1995)

Science.gov (United States)

Lilly, S. J.; Le Fevre, O.; Crampton, D.; Hammer, F.; Tresse, L.

2001-11-01

The Canada-France Redshift Survey (CFRS) is a collaboration between astronomers in Canada and France: Simon Lilly (University of Toronto), Olivier Le Fevre and Francois Hammer (Observatoire de Paris Meudon), David Crampton (Dominion Astrophysical Observatory, Victoria), Laurence Tresse (Cambridge University), and David Schade and Dan Hudon (University of Toronto). The survey is based primarily on observations with the 3.6m Canada-France-Hawaii Telescope (CFHT) on Mauna Kea, Hawaii. The CFRS consists of spectra of over 1000 faint objects selected to have 17.5 study of normal galaxies at redshifts z > 0.5, corresponding to look-back times of greater than 50% of the age of the Universe. Observations of CFRS galaxies have also been made with the Hubble Space Telescope and the survey will form the basis of future studies with a number of other ground-based and space facilities. We have written a lay-persons guide to the CFRS and the main scientific results that are emerging from it. (1 data file).

Practical guidebook for the obtention of an hydrocarbon exploration permit in France; Guide pratique pour l'obtention d'un permis de recherche d'hydrocarbures en France

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-07-01

Hydrocarbon exploration and production activity in France has become more attractive thanks to a better legal and fiscal environment. The reform of the mining code decided by the parliament in spring 1994 allows to greatly simplify the procedure of exploration permits obtention with a delay reduced to less than one year and more compatible with oil companies decision processes. Also, the specific fiscal system allows an equitable share of the mining profit. Since 1994, the oil and gas potentials of the sedimentary basins of the French territory (including its overseas territories) have been reevaluated and it appears that most basins remain incompletely or badly explored. Thus, the aim of this guidebook is to facilitate the administrative procedures of permits demand and to give a general overview of the legal, fiscal and geologic aspects of hydrocarbon exploration in France: 1 - exploration permits demand (dossier, relevant documents, administrative procedure), 2 - the legal framework (exploration: permit extension, change of farm-in partnership, production), 3 - the fiscal framework (progressive mining taxes, communal and departmental mining taxes, reinvestment incentives), 4 - geologic framework (Aquitaine and Paris basins, new opportunities). (J.S.)

Gaz de France first quarter 2007 sales: an 11 per cent drop due to an exceptionally warm winter: a 1.3 per cent increase on an average-climate basis. Non-audited IFRS data

Energy Technology Data Exchange (ETDEWEB)

NONE

2007-07-01

Paris, May 14 2007 - For the first quarter 2007, Gaz de France Group posted euro 9,053 million in consolidated sales. This 11 per cent decrease on the same period in 2006 is a direct result of the extremely warm weather conditions in France and Europe this winter. In contrast, under average climate conditions sales improved by 1.3 per cent. In France, where the winter of 2006/2007 was the warmest in fifty years, sales were impacted by 18 billion kWh in the quarter compared to a quarter with average-climate conditions and 32 billion kWh compared to the first quarter 2006 which, in contrast, was colder than normal. The impact of the weather had similar effects on sales outside France. The highly unusual weather conditions also had an indirect impact on the market and, consequently, on both gas production and the arbitrage activities. Not withstanding these effects, the Group continued to consolidate its position in foreign markets, with sales outside France reaching euro 3,341 million. The share of sales outside France increased by 3 points in the first quarter of 2007 versus first quarter 2006 to 37 per cent as at end March 2007. The group reiterates the 2007 financial objective as presented at the full year 2006 results: '2007 will be a year of consolidation and the EBITDA should be in line with that of 2006'.

Gaz de France first quarter 2007 sales: an 11 per cent drop due to an exceptionally warm winter: a 1.3 per cent increase on an average-climate basis. Non-audited IFRS data

International Nuclear Information System (INIS)

2007-01-01

Paris, May 14 2007 - For the first quarter 2007, Gaz de France Group posted euro 9,053 million in consolidated sales. This 11 per cent decrease on the same period in 2006 is a direct result of the extremely warm weather conditions in France and Europe this winter. In contrast, under average climate conditions sales improved by 1.3 per cent. In France, where the winter of 2006/2007 was the warmest in fifty years, sales were impacted by 18 billion kWh in the quarter compared to a quarter with average-climate conditions and 32 billion kWh compared to the first quarter 2006 which, in contrast, was colder than normal. The impact of the weather had similar effects on sales outside France. The highly unusual weather conditions also had an indirect impact on the market and, consequently, on both gas production and the arbitrage activities. Not withstanding these effects, the Group continued to consolidate its position in foreign markets, with sales outside France reaching euro 3,341 million. The share of sales outside France increased by 3 points in the first quarter of 2007 versus first quarter 2006 to 37 per cent as at end March 2007. The group reiterates the 2007 financial objective as presented at the full year 2006 results: '2007 will be a year of consolidation and the EBITDA should be in line with that of 2006'

18O and 34S in the Upper Bartonium gypsum deposits of the Paris basin

International Nuclear Information System (INIS)

Fontes, J.C.; Letolle, R.

1976-01-01

Isotopic analyses ( 18 O and 34 S) of the Eocene gypsum from the Paris basin show a range beyond the normal Tertiary marine values. The possibility of a reduction process during diagenesis is discussed. A hypothesis of continental origin by leaching of Permotriassic deposits is proposed for this formation on the basis of a comparison of the isotopic contents recorded from Germany and eastern France

Mid-21st century air quality at the urban scale under the influence of changed climate and emissions: case studies for Paris and Stockholm

Science.gov (United States)

Markakis, K.; Valari, M.; Engardt, M.; Lacressonnière, G.; Vautard, R.; Andersson, C.

2015-10-01

Ozone, PM10 and PM2.5 concentrations over Paris, France and Stockholm, Sweden were modeled at 4 and 1 \\unit{km} horizontal resolutions respectively for the present and 2050 periods employing decade-long simulations. We account for large-scale global climate change (RCP-4.5) and fine resolution bottom-up emission projections developed by local experts and quantify their impact on future pollutant concentrations. Moreover, we identify biases related to the implementation of regional scale emission projections over the study areas by comparing modeled pollutant concentrations between the fine and coarse scale simulations. We show that over urban areas with major regional contribution (e.g., the city of Stockholm) the bias due to coarse emission inventory may be significant and lead to policy misclassification. Our results stress the need to better understand the mechanism of bias propagation across the modeling scales in order to design more successful local-scale strategies. We find that the impact of climate change is spatially homogeneous in both regions, implying strong regional influence. The climate benefit for ozone (daily average and maximum) is up to -5 % for Paris and -2 % for Stockholm city. The joined climate benefit on PM2.5 and PM10 in Paris is between -10 and -5 % while for Stockholm we observe mixed trends up to 3 % depending on season and size class. In Stockholm, emission mitigation leads to concentration reductions up to 15 % for daily average and maximum ozone and 20 % for PM and through a sensitivity analysis we show that this response is entirely due to changes in emissions at the regional scale. On the contrary, over the city of Paris (VOC-limited photochemical regime), local mitigation of NOx emissions increases future ozone concentrations due to ozone titration inhibition. This competing trend between the respective roles of emission and climate change, results in an increase in 2050 daily average ozone by 2.5 % in Paris. Climate and not

Mid-21st century air quality at the urban scale under the influence of changed climate and emissions - case studies for Paris and Stockholm

Science.gov (United States)

Markakis, Konstantinos; Valari, Myrto; Engardt, Magnuz; Lacressonniere, Gwendoline; Vautard, Robert; Andersson, Camilla

2016-02-01

Ozone, PM10 and PM2.5 concentrations over Paris, France and Stockholm, Sweden were modelled at 4 and 1 km horizontal resolutions respectively for the present and 2050 periods employing decade-long simulations. We account for large-scale global climate change (RCP-4.5) and fine-resolution bottom-up emission projections developed by local experts and quantify their impact on future pollutant concentrations. Moreover, we identify biases related to the implementation of regional-scale emission projections by comparing modelled pollutant concentrations between the fine- and coarse-scale simulations over the study areas. We show that over urban areas with major regional contribution (e.g. the city of Stockholm) the bias related to coarse-scale projections may be significant and lead to policy misclassification. Our results stress the need to better understand the mechanism of bias propagation across the modelling scales in order to design more successful local-scale strategies. We find that the impact of climate change is spatially homogeneous in both regions, implying strong regional influence. The climate benefit for ozone (daily mean and maximum) is up to -5 % for Paris and -2 % for Stockholm city. The climate benefit on PM2.5 and PM10 in Paris is between -5 and -10 %, while for Stockholm we estimate mixed trends of up to 3 % depending on season and size class. In Stockholm, emission mitigation leads to concentration reductions up to 15 % for daily mean and maximum ozone and 20 % for PM. Through a sensitivity analysis we show that this response is entirely due to changes in emissions at the regional scale. On the contrary, over the city of Paris (VOC-limited photochemical regime), local mitigation of NOx emissions increases future ozone concentrations due to ozone titration inhibition. This competing trend between the respective roles of emission and climate change, results in an increase in 2050 daily mean ozone by 2.5 % in Paris. Climate and not emission change

Partitioning behaviour of perfluorinated alkyl contaminants between water, sediment and fish in the Orge River (nearby Paris, France)

International Nuclear Information System (INIS)

Labadie, Pierre; Chevreuil, Marc

2011-01-01

This paper reports on the partitioning behaviour of 15 perfluorinated compounds (PFCs), including C 4 -C 10 sulfonates and C 5 -C 14 carboxylic acids, between water, sediment and fish (European chub, Leuciscus cephalus) in the Orge River (nearby Paris). Total PFC levels were 73.0 ± 3.0 ng L -1 in water and 8.4 ± 0.5 ng g -1 in sediment. They were in the range 43.1-4997.2 ng g -1 in fish, in which PFC tissue distribution followed the order plasma > liver > gills > gonads > muscle. Sediment-water distribution coefficients (log K d ) and bioaccumulation factors (log BAF) were in the range 0.8-4.3 and 0.9-6.7, respectively. Both distribution coefficients positively correlated with perfluoroalkyl chain length. Field-based biota-sediment accumulation factors (BSAFs) are also reported, for the first time for PFCs other than perfluorooctane sulfonate. log BSAF ranged between -1.3 and 1.5 and was negatively correlated with the perfluoroalkyl chain length in the case of carboxylic acids. - Research highlights: → PFC tissue distribution in European chub followed the order plasma > liver > gills > gonads > muscle. → K d and BAF correlated with PFC alkyl chain length. → BSAF negatively correlated with the perfluoroalkyl chain length in the case of carboxylic acids. → BSAF did not correlate with alkyl chain length of sulfonates. - Sediment-water, biota-water and biota-sediment partitioning coefficients were determined for perfluorinated acids and sulfonates and were generally correlated with alkyl chain length.

Climate - 30 questions to understand the Paris Conference

International Nuclear Information System (INIS)

Canfin, Pascal; Staime, Peter

2015-01-01

The authors, who participate in the negotiations on climate, propose an analysis and a description of the various geopolitical, economic and financial challenges which are part of the next conference on climate (Conference of Parties, COP 21) which is to take place in France in December 2015. They notably discuss to which extent France is an example, what Obama can do, why things are changing in China, who are the opponents in the struggle against climate change. While one of the main issue of this conference, and the possible cause of its failure, will be the financial issue, and particularly the promise made in 2009 to mobilise 100 billions dollars every year in favour of developing countries which are the most impacted by global warming, in an interview, one of the author evokes the content of his book: he discusses the general consensus about the human origin of climate change, evokes fossil industries and oil producing countries as opponents to an energy revolution, outlines that energy transition is at the heart of what he calls the Battle of Paris (the conference), outlines the important role France can play despite some weaknesses of its climate policy, the new momentum given by China and the USA. He considers low carbon economy as the main world challenge on the long term

Aerosol particle measurements at three stationary sites in the megacity of Paris during summer 2009: meteorology and air mass origin dominate aerosol particle composition and size distribution

Directory of Open Access Journals (Sweden)

F. Freutel

2013-01-01

Full Text Available During July 2009, a one-month measurement campaign was performed in the megacity of Paris. Amongst other measurement platforms, three stationary sites distributed over an area of 40 km in diameter in the greater Paris region enabled a detailed characterization of the aerosol particle and gas phase. Simulation results from the FLEXPART dispersion model were used to distinguish between different types of air masses sampled. It was found that the origin of air masses had a large influence on measured mass concentrations of the secondary species particulate sulphate, nitrate, ammonium, and oxygenated organic aerosol measured with the Aerodyne aerosol mass spectrometer in the submicron particle size range: particularly high concentrations of these species (about 4 μg m⁻³, 2 μg m⁻³, 2 μg m⁻³, and 7 μg m⁻³, respectively were measured when aged material was advected from continental Europe, while for air masses originating from the Atlantic, much lower mass concentrations of these species were observed (about 1 μg m⁻³, 0.2 μg m⁻³, 0.4 μg m⁻³, and 1–3 μg m⁻³, respectively. For the primary emission tracers hydrocarbon-like organic aerosol, black carbon, and NO_x it was found that apart from diurnal source strength variations and proximity to emission sources, local meteorology had the largest influence on measured concentrations, with higher wind speeds leading to larger dilution and therefore smaller measured concentrations. Also the shape of particle size distributions was affected by wind speed and air mass origin. Quasi-Lagrangian measurements performed under connected flow conditions between the three stationary sites were used to estimate the influence of the Paris emission plume onto its surroundings, which was found to be rather small. Rough estimates for the impact of the Paris emission plume on the suburban areas can be

Relationships between respiratory and airway resistances and activity-related dyspnea in patients with chronic obstructive pulmonary disease

Directory of Open Access Journals (Sweden)

Plantier L

2012-03-01

Full Text Available Bruno Mahut1,2, Aurore Caumont-Prim3,4, Laurent Plantier1,5, Karine Gillet-Juvin1,6, Etienne Callens1, Olivier Sanchez5,6, Brigitte Chevalier-Bidaud3, Plamen Bokov1, Christophe Delclaux1,5,71Assistance Publique – Hôpitaux de Paris (AP-HP, Hôpital Européen Georges Pompidou, Service de Physiologie – Clinique de la Dyspnée, F-75015 Paris, France; 2Cabinet La Berma, 4 avenue de la Providence; F-92160 Antony, France; 3AP-HP, Hôpital Européen Georges Pompidou, Unité d'Épidémiologie et de Recherche Clinique, F-75015 Paris, France; 4INSERM, Centre d'Investigation Épidémiologique 4, F-75015 Paris, France; 5Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine, F-75015 Paris, France; 6AP-HP, Hôpital Européen Georges Pompidou, Service de Pneumologie; F-75015 Paris, France; 7CIC 9201 Plurithématique, Hôpital Européen Georges Pompidou, F-75015 Paris, FranceBackground: The aims of the study were: (1 to compare numerical parameters of specific airway resistance (total, sRawtot, effective, sRaweff and at 0.5 L • s-1, sRaw0.5 and indices obtained from the forced oscillation technique (FOT: resistance extrapolated at 0 Hz [Rrs0 Hz], mean resistance [Rrsmean], and resistance/frequency slope [Rrsslope] and (2 to assess their relationships with dyspnea in chronic obstructive pulmonary disease (COPD.Methods: A specific statistical approach, principal component analysis that also allows graphic representation of all correlations between functional parameters was used. A total of 108 patients (mean ± SD age: 65 ± 9 years, 31 women; GOLD stages: I, 14; II, 47; III, 39 and IV, 8 underwent spirometry, body plethysmography, FOT, and Medical Research Council (MRC scale assessments.Results: Principal component analysis determined that the functional parameters were described by three independent dimensions (airway caliber, lung volumes and their combination, specific resistance and that resistance parameters of the two techniques

French Revolution or Industrial Revolution? A Note on the Contrasting Experiences of England and France up to 1800

OpenAIRE

Paul R. Sharp; Jacob L. Weisdorf

2011-01-01

At the end of the eighteenth century, England and France both underwent revolutions: France the French Revolution, England the industrial revolution. This note sheds new light on these contrasting experiences in the histories of England and France by looking at the evolution of real consumer prices in London and Paris in the centuries leading up to 1800. Whilst in London, building workers were facing low and stable consumer prices over the period, leaving plenty of scope for a demand-driven c...

Hauts-de-France. A pioneer in the French energy transition

International Nuclear Information System (INIS)

Falk, Thomas

2016-01-01

France had established in advance of last year's climate summit in Paris on ambitious energy policy goals. Especially the 2016 newly formed Region Hauts-de-France stands out as a pioneer here. There one drives innovation and investments with the objective of fulfilling by 2050 their own needs completely by renewable sources. The orientation to supplies Jeremy Rifkin idea of the third industrial revolution. If successful, the region would be on climate protection well ahead of the national targets, the 2050 ''only'' provide a CO 2 emission reduction of 75%. In addition to the Research and development (R and D) to many future ideas in Hauts-de-France but also some major projects for Security of European energy supplies are realized that show the local agility. [de

Nuclear Education in France

International Nuclear Information System (INIS)

Guet, C.

2013-01-01

This series of slides draws a picture of nuclear engineering training in France. The nuclear sector is very active and developed in France and covers all the aspects of the fuel cycle which implies a strong demand for highly skilled and trained staff. There are both an active involvement of industry in the education process through the design of adequate curricula and a strong support of the State. There are 5 masters dedicated to Science Nuclear Energy (Paris), Nuclear Waste Management (Nantes), Separation Chemistry (Montpellier), Materials for Nuclear Engineering (Grenoble), and 1 engineer degree in nuclear engineering (Saclay). In 2010-2011 there were about 1000 students completing a nuclear energy curriculum (nuclear engineering or specialized nuclear domains) at the master-engineer level throughout France. The detailed curriculum of the Master of Science Nuclear Energy is given. The National Institute of Nuclear Sciences and Techniques (INSTN) plays an important role, it has trained a large fraction of the French leading nuclear practitioners through its 50 years old 'Genie Atomique' curriculum. INSTN proposes also high level courses in nuclear disciplines including training of nuclear physicians, radio-pharmacists and medical physicists and is a major player for continuing education in nuclear sciences. (A.C.)

''La Grande Galerie de l'Evolution'' of Paris: The only museum in the world entirely devoted to biological evolution

International Nuclear Information System (INIS)

Raulin Cerceau, F.

1995-01-01

The new building called ''Grande Galerie de l'Evolution'' of the national Museum of natural History, in Paris-France, is the first museum in the world exclusively devoted to biological evolution. The Museum is divided in 3 parts (named ''Acts''): The aim of Act 1 is to sensibilize the visitor to the results of 4 billions years of biological evolution. This act shows some examples of biological diversity through few terrestrial and marine environments (deserts, tropical forests, polar habitats, abyssal zones ...). Act 2 is the principal part of the Museum explaining the main processes of evolution. This part shows also the story of life from the first living cells to man. Act 3, the last part offers to visitors a vision of the interactions between man and nature, and of their consequences along millions of years. A special Gallery is entirely devoted to vanished and threatened species, as a nefast consequence of human interaction on biological diversity particularly since the beginning of this century. (Abstract only)

Retrospective observational study of emergency department syndromic surveillance data during air pollution episodes across London and Paris in 2014.

Science.gov (United States)

Hughes, Helen E; Morbey, Roger; Fouillet, Anne; Caserio-Schönemann, Céline; Dobney, Alec; Hughes, Thomas C; Smith, Gillian E; Elliot, Alex J

2018-04-19

Poor air quality (AQ) is a global public health issue and AQ events can span across countries. Using emergency department (ED) syndromic surveillance from England and France, we describe changes in human health indicators during periods of particularly poor AQ in London and Paris during 2014. Using daily AQ data for 2014, we identified three periods of poor AQ affecting both London and Paris. Anonymised near real-time ED attendance syndromic surveillance data from EDs across England and France were used to monitor the health impact of poor AQ.Using the routine English syndromic surveillance detection methods, increases in selected ED syndromic indicators (asthma, difficulty breathing and myocardial ischaemia), in total and by age, were identified and compared with periods of poor AQ in each city. Retrospective Wilcoxon-Mann-Whitney tests were used to identify significant increases in ED attendance data on days with (and up to 3 days following) poor AQ. Almost 1.5 million ED attendances were recorded during the study period (27 February 2014 to 1 October 2014). Significant increases in ED attendances for asthma were identified around periods of poor AQ in both cities, especially in children (aged 0-14 years). Some variation was seen in Paris with a rapid increase during the first AQ period in asthma attendances among children (aged 0-14 years), whereas during the second period the increase was greater in adults. This work demonstrates the public health value of syndromic surveillance during air pollution incidents. There is potential for further cross-border harmonisation to provide Europe-wide early alerting to health impacts and improve future public health messaging to healthcare services to provide warning of increases in demand. © Crown copyright 2018. Reproduced with the permission of the Controller of Her Majesty’s Stationery Office/Queen’s Printer for Scotland and Public Health England.

In situ, satellite measurement and model evidence on the dominant regional contribution to fine particulate matter levels in the Paris megacity

NARCIS (Netherlands)

Beekmann, M.; Prévôt, A.S.H.; Drewnick, F.; Sciare, J.; Pandis, S.N.; Denier van der Gon, H.A.C.; Crippa, M.; Freutel, F.; Poulain, L.; Ghersi, V.; Rodriguez, E.; Beirle, S.; Zotter, P.; Weiden-Reinmüller, S.L. von der; Bressi, M.; Fountoukis, C.; Petetin, H.; Szidat, S.; Schneider, J.; Rosso, A.; El Haddad, I.; Megaritis, A.; Zhang, Q.J.; Michoud, V.; Slowik, J.G.; Moukhtar, S.; Kolmonen, P.; Stohl, A.; Eckhardt, S.; Borbon, A.; Gros, V.; Marchand, N.; Jaffrezo, J.L.; Schwarzenboeck, A.; Colomb, A.; Wiedensohler, A.; Borrmann, S.; Lawrence, M.; Baklanov, A.; Baltensperger, U.

2015-01-01

A detailed characterization of air quality in the megacity of Paris (France) during two 1-month intensive campaigns and from additional 1-year observations revealed that about 70 % of the urban background fine particulate matter (PM) is transported on average into the megacity from upwind regions.

Disability related to COPD tool (DIRECT: towards an assessment of COPD-related disability in routine practice

Directory of Open Access Journals (Sweden)

Aguilaniu B

2011-07-01

Full Text Available B Aguilaniu1, J Gonzalez-Bermejo2, A Regnault3, C Dias Barbosa3, B Arnould3, M Mueser4, G Granet5, M Bonnefoy6, T Similowski2,71HYLAB, Physiologie Clinique, Grenoble, France; 2Assistance Publique – Hôpitaux de Paris, Groupe Hospitalier Pitié-Salpêtrière, Service de Pneumologie et Réanimation, Paris, France; 3Mapi Values, Lyon, France; 4Formerly Boehringer Ingelheim, Paris, France; 5General Practitioner, Sainte-Foy-lès-Lyon, Paris, France; 6Centre Hospitalier Lyon Sud, Lyon, France; 7Université Paris 6 Pierre et Marie Curie, ER10, Paris, FranceBackground: Chronic Obstructive Pulmonary Disease (COPD is a worldwide public health concern. It is also a major source of disability that is often overlooked, depriving patients of effective treatments. This study describes the development and validation of a questionnaire specifically assessing COPD-related disability.Methods: The DIsability RElated to COPD Tool (DIRECT was developed according to reference methods, including literature review, patient and clinician interviews and test in a pilot study. A 12-item questionnaire was included for finalization and validation in an observational cross-sectional study conducted by 60 French pulmonologists, who recruited 275 COPD patients of stage II, III and IV according to the GOLD classification. Rasch modeling was conducted and psychometric properties were assessed (internal consistency reliability; concurrent and clinical validity.Results: The DIRECT score was built from the 10 items retained in the Rasch model. Their internal consistency reliability was excellent (Cronbach's alpha = 0.95. The score was highly correlated with the Saint George's Respiratory Questionnaire Activity score (r = 0.83 and the London Handicap Scale (r = –0.70, a generic disability measure. It was highly statistically significantly associated to four clinical parameters (P < 0.001: GOLD classification, BODE index, FEV1 and 6-minute walk distance.Conclusion: DIRECT is a

Two months of disdrometer data in the Paris area

Science.gov (United States)

Gires, Auguste; Tchiguirinskaia, Ioulia; Schertzer, Daniel

2018-05-01

The Hydrology, Meteorology, and Complexity laboratory of École des Ponts ParisTech (hmco.enpc.fr) has made a data set of optical disdrometer measurements available that come from a campaign involving three collocated devices from two different manufacturers, relying on different underlying technologies (one Campbell Scientific PWS100 and two OTT Parsivel2 instruments). The campaign took place in January-February 2016 in the Paris area (France). Disdrometers provide access to information on the size and velocity of drops falling through the sampling area of the devices of roughly a few tens of cm2. It enables the drop size distribution to be estimated and rainfall microphysics, kinetic energy, or radar quantities, for example, to be studied further. Raw data, i.e. basically a matrix containing a number of drops according to classes of size and velocity, along with more aggregated ones, such as the rain rate or drop size distribution with filtering, are available. Link to the data set: https://zenodo.org/record/1240168" target="_blank">https://zenodo.org/record/1240168 (DOI: https://doi.org/10.5281/zenodo.1240168" target="_blank">https://doi.org/10.5281/zenodo.1240168).

De Paris à Lyon. Les mutations éditoriales du «Lancelot du Lac»

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Gaëlle Burg

2015-07-01

Full Text Available Lancelot du Lac est le premier roman arthurien imprimé à la Renais­sance. Dans sa première édition parue en 1488, qui réunit deux imprimeurs (Jean Le Bourgeois à Rouen et Jean Du Pré à Paris, un découpage et un prologue inédits sont ajoutés par le remanieur. Le texte sera réédité six fois par divers imprimeurs-libraires parisiens jusqu’en 1533. L’édition de luxe d’Antoine Vérard (1494, destinée au roi Charles VIII, présente d’importantes modifications effectuées dans un but commercial. Après une longue période d’accalmie qui signe le début du déclin de la vogue des romans de chevalerie médiévaux, Benoît Rigaud publie à Lyon, sous une forme considérablement abrégée, la dernière édition connue du Lancelot au XVIe siècle (1591. Si elle ne présente que peu d’intérêt littéraire, elle apporte cependant des informations concernant les pratiques éditoriales et les goûts du  lecteur de la fin du XVIe siècle. De Paris à Lyon, entre renaissance et déclin, le parcours éditorial d’un incontournable roman arthurien.Lancelot du Lac is the editio princeps of an Arthurian romance in Renaissance France. The first edition in 1488, which brings together two printers (Jean Le Bourgeois from Rouen and Jean Du Pré from Paris, offers original arrangement and prologue added by the compositor. The text will be published six times by various printers and booksellers in Paris until 1533. The luxurious edition from Antoine Vérard (1494 dedicated to King Charles VIII provides interesting transformations in commercial purposes. After a long time without edition, showing the beginning of chivalry literature’s decline, Benoît Rigaud publish in Lyon, in a greatly abbreviated form, the last known edition of Lancelot in the XVIth century (1591. If it presents no literary interest, it provides nevertheless informations about editorial practices and reader’s tastes from the end of Renaissance France. From Paris to

Analyse séquentielle de l'Eocène et de l'Oligocène du bassin Parisien (France Sequence Analysis of the Eocene-Oligocene Paris Basin, France

Directory of Open Access Journals (Sweden)

Gely J. P.

2006-11-01

has as yet only been roughly sketched out. The survey was not based on seismic profiles because the Parisian Tertiary series outcrop. Therefore, our analysis is based on field observations and the abundant bibliography dealing with the Paris Basin. Recent dating of different depositional systems for each sequence is mainly due to the determining of Wetzelliaceae (J. J. Châteauneuf and C. Gruas-Cavagnetto, 1968; J. J. Châteauneuf, 1980, calcareous nannofossils (M. P. Aubry, 1983, 1985; E. Steurbaut, 1988, Characea (J. Riveline, 1984, mollusca and mammalia (C. Cavelier, 1979, 1987. We propose a time section (Plate 1 and Figs. 1 to 21 and a paleogeographic map (Maps 2 to 18 for each depositional sequence. There are 22 unconformities corresponding to large sedimentation gaps during the Eocene and Oligocene (Plate 1. They are the results of emersions and correspond to low sea levels when the sediments were situated solely in lowstand prograduring wedges or on the Shelf margin wedge but rarely present in the Paris Basin [Sequences 1 (Fig. 1, 3 (Fig. 3, 19 (Fig. 19 and 20 (Fig. 20]. These unconformities, bounded by depositional sequences, are often confused with transgressive surfaces on the Paris shelf and are usually revealed by erosional surfaces as well as by the presence of paleolkarsts, paleosols, eolian reworking or sandstone diagenesis. Unconformities at the Thanetian-Sparnacian, upper Cuisian-Terminal Cuisian, Cuisian-Lutetian, Mrinesian-Ludian, Ludian-Stampian and Stampian-Chattian boundaries can be recognized from the Type 1 (Plate 1. In the Paris Basin, these unconformities are major ones separating most of the stratotypic sequences. The other sequences are reparated by a Type 2 unconformity with local subaerial erosion on the edges of the Paris Gulf or on the entire area of the basin (Sequences 3, 4, 7, 8, 10, 11, 14, 17, 18, 19 and 20 depending on the eustatic fall and the subsidence. The presence of rivers, mainly issuing from the South and East of the basin

1997 annual report. Petroleum research and production in France; Rapport annuel 1997. Recherche et production petrolieres en France

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-12-31

The efforts expended during the previous years for the renewal of oil and gas exploration in France led to a significant increase in the number of applications for exploration permits: 8 against 2 in 1996. A renewing interest for the French offshore mining acreage is observed in Sea of Iroise, Saint-Pierre and Miquelon and in the Bay of Biscay. The total number of valid production permits has slightly dropped (76 against 77 in 1996) and is divided into 55 concessions and 21 production permits. A 42% decline of exploration investments is observed as compared to the previous year. The geophysical prospecting sector has been particularly affected but the exploration drilling activity has been marked by a new discovery realized with the Tamaris 1D well on the Lege permit held jointly by Esso Rep and Elf Aquitaine. However the level of exploration drilling activity is much lower than in 1996 (3 wells completed against 7 in 1996). A 59% increase in investments production is due to the put on stream of the Courbey discovery (Arcachon basin) and to the arrival of new operators on the French mining acreage. The infill drilling activity has shown a significant increase linked to these events with 8 completed wells. The Paris basin remains the main oil producing area in France (1.026 million tons) but is affected by a 18.2% decline compared with 1996, higher than the Aquitaine basin decline (11.8%). Natural gas production has decreased by 8.4% due to the decline of the Lacq and Meillon main gas fields. (J.S.)

1997 annual report. Petroleum research and production in France; Rapport annuel 1997. Recherche et production petrolieres en France

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-12-31

The efforts expended during the previous years for the renewal of oil and gas exploration in France led to a significant increase in the number of applications for exploration permits: 8 against 2 in 1996. A renewing interest for the French offshore mining acreage is observed in Sea of Iroise, Saint-Pierre and Miquelon and in the Bay of Biscay. The total number of valid production permits has slightly dropped (76 against 77 in 1996) and is divided into 55 concessions and 21 production permits. A 42% decline of exploration investments is observed as compared to the previous year. The geophysical prospecting sector has been particularly affected but the exploration drilling activity has been marked by a new discovery realized with the Tamaris 1D well on the Lege permit held jointly by Esso Rep and Elf Aquitaine. However the level of exploration drilling activity is much lower than in 1996 (3 wells completed against 7 in 1996). A 59% increase in investments production is due to the put on stream of the Courbey discovery (Arcachon basin) and to the arrival of new operators on the French mining acreage. The infill drilling activity has shown a significant increase linked to these events with 8 completed wells. The Paris basin remains the main oil producing area in France (1.026 million tons) but is affected by a 18.2% decline compared with 1996, higher than the Aquitaine basin decline (11.8%). Natural gas production has decreased by 8.4% due to the decline of the Lacq and Meillon main gas fields. (J.S.)

Aims and first assessments of the French hydrogen pathways project HyFrance3

Energy Technology Data Exchange (ETDEWEB)

Le Duigou, Alain [CEA/DEN/DANS/I-Tese, Gif-sur-Yvette (France); Quemere, Marie-Marguerite [EDF R et D, Moret sur Loing (France). Dept. EPI; Marion, Pierre [IFP, Rueil Malmaison (FR)] (and others)

2010-07-01

The HyFrance Group was originally formed in France to support the European project HyWays, by providing (former projects HyFrance1 and HyFrance2) the French data and possible hydrogen pathways according to national specificities. HyFrance3 is a new project that focuses on the economic competitiveness of different steps of the hydrogen chain, from the production to end usage, at the time horizon of 2030 in France. The project is coordinated by CEA with the other partners being: ADEME (co-funding), AFH2, CNRS, IFP, Air Liquide, EdF, GdF Suez, TOTAL, ALPHEA. The project is divided into 4 sub-projects, that address present and future French hydrogen industrial markets for chemical and refinery uses, the analysis of the interplay between wind energy production and storage of hydrogen for different automotive requirements (refuelling stations, BtL plants, H2/NG mix), massive hydrogen storage to balance various offer and demand characteristics, and the supply network (pipeline option competitiveness vs. trucked in supply) to distribute hydrogen in a French region for automotive applications. Technical and economical issues, as well as GHG emissions, are addressed. (orig.)

Intergovernmental Conference of Experts on the Scientific Basis for Rational Use and Conservation of the Resources of the Biosphere (Paris, France, September 4-13, 1968), Recommendations.

Science.gov (United States)

United Nations Educational, Scientific, and Cultural Organization, Paris (France).

This document contains twenty recommendations put forth at the Intergovernmental Conference of Experts on the Scientific Basis for Rational Use and Conservation of the Resources of the Biosphere under the direction of UNESCO (United Nations Educational, Scientific and Cultural Organization). The conference was held at the UNESCO House, Paris,…

Gambling in revolutionary Paris - The Palais Royal: 1789-1838.

Science.gov (United States)

Barnhart, R T

1992-06-01

By the revolution of 1789, the four-story, quadrangular Palais Royal in Paris had become the most glittering tourist center of Europe, with 180 shops and cafes in its ground floor arcades. By 1791, its basement and secondary story contained over 100 separate, illicit gambling operations featuring the most popular dice and card games. The mania for gambling had been transferred from defunct, monarchical Versailles to the thriving, bourgeois Palais Royal, where the five main gaming clubs throbbed from noon till midnight. During the Revolution, Prince Talleyrand won 30,000 francs at one club, and after Waterloo in 1815, Marshal Blucher lost 1,500,000 francs in one night at another. To bring the situation under control and raise taxes for the state, in 1806 Napoleon legalized the main clubs, which from 1819 to 1837 grossed an enormous 137 million francs. When the anti-gambling forces triumphed in 1837 and the clubs were closed down, the National Guard had to be called out to evict the mobs of gamblers who refused to leave the tables. Dramatic reports from Revolutionary police raids, and quotations from the memoirs of humorous French gamblers and shocked foreign visitors, provide anecdotal illustrations of the 49 years during which the Palais Royal was the most intriguing and picturesque gambling mecca of Europe-and probably of the world.

Research aspects in the Paris-Sud University, in 1988

International Nuclear Information System (INIS)

1988-01-01

Some of the research works developed in the Paris-Sud University, in 1988, are reported. In this second volume, the following research papers are presented: the antiprogesterone; the English Channel Tunnel; the individual will concerning filiation; the glycannic variations of the α 1; the molecular phylogenies; the adrenergetical transmission and the β receptors; the organical phases and crystallogenesis in the carbonaceous biomineralizations; the quarks electric charge determination; the X-imagery; the regulation of the enzymatic activities by light in the superior vegetals; the chemical reaction dynamical analysis; the experiment report concerning heavy ions - high density plasma interactions; the 13 C/ 12 C isotopic splitting during photosynthesis; the articular prothesis methodology; and the public authorities and commerce in France [fr

Les arts en France autour de 1400. Création artistique, questions iconographiques

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Daniel Russo

2005-10-01

Full Text Available Durant le printemps et l’été 2004, cinq grandes expositions ont montré la très grande richesse des arts en France, sous le règne de Charles VI (1368-1422, roi de 1380 à 1422, et d’Isabeau de Bavière (1371-1435, reine de 1385 à 1435. Une forte insistance fut mise sur le foyer parisien (Paris 1400. Les arts sous Charles VI, musée du Louvre, Paris, 22 mars-12 juillet, sous le commissariat d’Élisabeth Taburet-Delahaye, mais aussi, et ce fut une grande originalité, sur les principaux foyers sit...

The Rise of Massage and Medical Gymnastics in London and Paris before the First World War.

Science.gov (United States)

Quin, Grégory

2017-01-01

Massage and medical gymnastics experienced a rapid institutionalization across Europe and North America between 1850 and 1914. This article explores how this process took place in London and Paris. Physiotherapy developed many of the hallmarks of an independent discipline during this period, including an identified corpus of manipulations and exercises, some autonomous training courses and degrees for future practitioners, and even the creation of departments within several hospitals. The article analyzes all of the processes surrounding this rise, paying special attention to the influence of the ambassadors of Swedish gymnastics (which led to the re-invention of massage across Europe), to the installation of physiotherapy in hospitals in London and in Paris, and to the practical and institutional innovations driven by nurses in England and by doctors in France.

Figures and Institutions of the neurological sciences in Paris from 1800 to 1950. Part IV: Psychiatry and psychology.

Science.gov (United States)

Poirier, J; Clarac, F; Barbara, J-G; Broussolle, E

2012-05-01

We present a short historical review on the major institutions and figures who contributed to make Paris a renowned centre of physiology and neurology during the XIXth and the first half of the XXth century. We purposely chose to focus on the period 1800-1950, as 1800 corresponds to the actual beginning of neurosciences, and as 1950 marks their exponential rise. Our presentation is divided into four chapters, matching the main disciplines that have progressed and contributed most to the knowledge we have of the brain sciences: anatomy, physiology, neurology, and psychiatry-psychology. The present article is the fourth of the four parts of this review, which deals with the chapter on psychiatry and psychology. When the French Revolution occurred, only a few institutions were taking care of the mentally ill. In the Paris area, these included Maison Royale de Charenton, Les Petites Maisons, and one of the departments of larger hospitals such as Hôtel-Dieu, the Salpêtrière Hospital and Bicêtre Hospital. One of the founders of psychiatry in Paris at that time and thereafter was Philippe Pinel (1745-1826) who was the first to distinguish insane/alienated patients from misfits, beggars, and other vagabonds. During the first half of the XIXth century, his student Jean-Étienne Esquirol (1772-1840) also played a major role with his treatise on mental diseases and the 1838 law and the creation of asylums in all parts of France. Alienists were in general caregivers and learned by themselves. In contrast, at the academic level, the emerging disciplines psychiatry and neurology were very close to each other in the second half of the XIXth century, the best example being Jules Baillarger (1809-1890). The actual development of psychiatry and psychology and the foundation of psychoanalysis later in the XIXth century and in the first half of the XXth century owed much to several European doctors and scientists, particularly those from British institutions and from German

Les débuts des relations "officielles" roumaines - françaises. La création de l'agence diplomatique roumaine à Paris (26 août / 7 septembre 1860

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Iulian Oncescu

2009-12-01

Full Text Available Institutionalization of diplomatic agents of the United Principalities in Paris was possible after the meeting held on August 26 / September 7 1860. After receiving the note from the Foreign Minister of Moldova, Mihail Jora, and a letter from Prince Cuza, French Foreign Minister, Ed. Thouvenel, said he was very happy to receive the staff of Prince Alexandru Ioan Cuza. Even so, he could not consider the Romanian Agent an official agent, because he would violate the 1858 Paris Convention, to which France participated. In this context, the United Principalities Agency was officially recognized and later became the Romanian Legation in Paris (1880.

Multi-parameter observation of environmental asbestos pollution at the Institut de Physique du Globe de Paris (Jussieu Campus, France).

Science.gov (United States)

Besson, P; Lalanne, F X; Wang, Y; Guyot, F

1999-11-01

An original multi-parameter system has been used to study the nature of dust in the ambient air, particularly the total fibers and asbestos fibers, in eight areas of the Institut de Physique de Globe de Paris (France). These analyses provide a detailed case study of environmental pollution by asbestos fibers at low levels. The levels of total fibers with a length greater than 3 microns, measured with a real time fiber analyser monitor (FAM), give a baseline of 2.5 fibers per l., throughout the duration of sampling. The same levels, calculated during periods of effective presence of staff, are smaller than 10 fb per l. During these periods, the instantaneous value can show high peaks, reaching a maximum of 60 fb per l., but more often of about 5 to 10 fb per l. A direct cause and effect relationship exists between fiber concentrations and the presence of people, and indirectly with the variation of the other environmental parameters (temperature, humidity, air velocity). The baseline concentration of asbestos fibers, determined by analytical transmission electron microscopy (ATEM), is about 10(-1) fb per l., with a mean value during the presence of people always less than 1.5 fb per l. The low levels of asbestos fibers do not allow us to establish a precise correlation between the concentration of total fibers and the asbestos concentration, but a rough estimate suggests that asbestos could represent 10-20% of the airborne fibers monitored with the FAM. The statistical study of fiber sizes shows that 70 and 55% of analyzed chrysotile and amosite fibers respectively are smaller than 5 microns. These numbers are 40 and 35% for fibers smaller than 3 microns, which are undetected by the FAM. Amosite, which characterizes most of the asbestos-containing materials (ACM) in the analyzed areas, is detected in the ambient air in quantities ten times less important than chrysotile. The low asbestos levels and the difference between the nature of building asbestos and airborne

Tropospheric and total ozone columns over Paris (France measured using medium-resolution ground-based solar-absorption Fourier-transform infrared spectroscopy

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C. Viatte

2011-10-01

Full Text Available Ground-based Fourier-transform infrared (FTIR solar absorption spectroscopy is a powerful remote sensing technique providing information on the vertical distribution of various atmospheric constituents. This work presents the first evaluation of a mid-resolution ground-based FTIR to measure tropospheric ozone, independently of stratospheric ozone. This is demonstrated using a new atmospheric observatory (named OASIS for "Observations of the Atmosphere by Solar absorption Infrared Spectroscopy", installed in Créteil (France. The capacity of the technique to separate stratospheric and tropospheric ozone is demonstrated. Daily mean tropospheric ozone columns derived from the Infrared Atmospheric Sounding Interferometer (IASI and from OASIS measurements are compared for summer 2009 and a good agreement of −5.6 (±16.1 % is observed. Also, a qualitative comparison between in-situ surface ozone measurements and OASIS data reveals OASIS's capacity to monitor seasonal tropospheric ozone variations, as well as ozone pollution episodes in summer 2009 around Paris. Two extreme pollution events are identified (on the 1 July and 6 August 2009 for which ozone partial columns from OASIS and predictions from a regional air-quality model (CHIMERE are compared following strict criteria of temporal and spatial coincidence. An average bias of 0.2%, a mean square error deviation of 7.6%, and a correlation coefficient of 0.91 is found between CHIMERE and OASIS, demonstrating the potential of a mid-resolution FTIR instrument in ground-based solar absorption geometry for tropospheric ozone monitoring.

Novel ambler class A carbapenem-hydrolyzing beta-lactamase from a Pseudomonas fluorescens isolate from the Seine River, Paris, France.

Science.gov (United States)

Girlich, Delphine; Poirel, Laurent; Nordmann, Patrice

2010-01-01

A Pseudomonas fluorescens isolate (PF-1) resistant to carbapenems was recovered during an environmental survey performed with water from the Seine River (Paris). It expressed a novel Ambler class A carbapenemase, BIC-1, sharing 68 and 59% amino acid identities with beta-lactamases SFC-1 from Serratia fonticola and the plasmid-encoded KPC-2, respectively. beta-Lactamase BIC-1 hydrolyzed penicillins, carbapenems, and cephalosporins except ceftazidime and monobactams. The bla(BIC-1) gene was chromosomally located and was also identified in two other P. fluorescens strains isolated from the Seine River 3 months later.

Key figures on climate France and Worldwide - 2017 Edition

International Nuclear Information System (INIS)

Baude, Manuel; Dussud, Francois-Xavier; Ecoiffier, Mathieu; Duvernoy, Jerome; Vailles, Charlotte; Moreau, Sylvain; Bottin, Anne; Hiblot, Guillaume

2016-10-01

In line with previous years, the 2017 edition of 'Key figures on climate' has been written in the context of the 22. Conference of the Parties on Climate Change (COP 22) held in Marrakech from 7 to 18 November 2016. This latest version, published as part of the new 'datalab' collection of the General commission for sustainable development was updated and expanded relative to the 2016 edition. New data sources have been used for the part on global CO_2 emissions. The part on climate policies was further developed, and notably deals with the Paris agreement adopted in December 2015 at COP 21. Moreover, the analysis of climate finance (current climate investments and climate finance needs) has been expanded. About the form, and with a goal of simplification, some data previously displayed in both a graph and a table is now presented only in a graph. Content: Part 1: What is climate change? This part summarizes the scientific basis of climate change, including indicators, causes and possible consequences of global warming. Part 2: Which amounts of greenhouse gases are emitted globally? The focus here is on the most relevant data related to global greenhouse gases (GHG) emissions, in particular the geographic distribution of these emissions. Part 3: How much greenhouse gas is emitted in Europe and in France? A complete overview of GHG emissions statistics in Europe and in France is presented in this part as well as estimates of the carbon footprint of French people. Part 4: What is the sectoral distribution of GHG emissions in Europe and in France? This part features the detailed evolution since 1990 of GHG emissions in the following economic sectors: energy sector, transports, industry, residential and tertiary, agriculture, forestry, land use and waste management. Part 5: Which climate policies in the world, in Europe and in France? The main climate policies are described at each level: global, European and French

Pengelolaan Sumberdaya Air untuk Pengembangan Pariwisata di Pulau Pari, Kepulauan Seribu, DKI Jakarta

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Roland Sinulingga

2016-09-01

Full Text Available ABSTRAK Penelitian bertujuan untuk (a menganalisis kondisi ketersediaan air di Pulau Pari, (b menganalisis kondisi kualitas air di Pulau Pari, (c menganalisis kebutuhan air dan proyeksinya untuk masa yang akan datang di Pulau Pari, dan (d merumuskan strategi pengelolaan sumberdaya air untuk pariwisata di Pulau Pari. Metode penelitian terdiri atas perhitungan neraca air, kebutuhan air, metode geometrik, analisis deskriptif, dan analisis SWOT. Pengambilan sampel air dan penduduk menggunakan metode purposive, sedangkan sampel wisatawan menggunakan metode accidental random sampling. Hasil akhir penelitian ketersediaan airtanah di Pulau Pari sebesar 290000,48 m3/tahun. Kualitas airtanah di lokasi penelitian tergolong baik. Besarnya kebutuhan air tahun 2013 sebesar 46381,947 m3/tahun. Pada tahun 2018 menjadi 54443,953 m3/tahun dan pada tahun 2023 mengalami peningkatan menjadi 63548,472 m3/tahun. Prioritas utama strategi pengelolaan sumberdaya air untuk pariwisata yaitu membuat kebijakan pembatasan pengunjung agar kelestarian pulau dan sumberdaya air tetap terjaga.   ABSTRACT This study aims to (a analyze water availability conditions in Pari Island, (b analyze the water quality conditions in Pari Island, (c analyze water demand and water projections for the future in Pari Island, and (d formulate strategies management water resources for tourism in Pari Island. The research method consists of the calculation of the water balance, water requirements, geometric methods, descriptive analysis, and SWOT analysis. Water sampling and settlement using purposive method, tourist’s samples using accidental random sampling. The final results of The amount of soil water availability in Pari Island of 290000,48 m3 / year. Groundwater quality in the study area are classified as good. The amount of water demand in 2013 amounted to 46381,947 m3 / year. In 2018 became 54443,953 m3 / year and in 2023 increased to 63548,472 m3 / year. First priority water resource

Soviet-France cooperative study of the solar corona

International Nuclear Information System (INIS)

Vsekhvsyatskij, S.K.; Dzyubenko, N.I.; Ivanchuk, V.I.; Popov, O.S.; Rubo, G.A.; Kuchmij, S.; Kuchmij, O.; Shtel'makher, G.

1981-01-01

The study continues the investigations on the solar corona performed according to the program of the Soviet-France experiment ''The white corona dynamics'' during total solar eclipses on July 10 1972 and June 30, 1973 by the expeditions of Kiev University and Paris Astrophysical Institute. The results of the study of eclipse negatives obtained on June 30 1973 in Africa are given. On the basis of new methods of photometry and colorimetry using star images up to 8.5sup(m) as the photometry standards it has been found with high accuracy the distribution of the total corona brightness up to r approximately equal to 4.5 Rsub(S) and its K- and F-corona components for E and N directions. Neither color effect nor flattening is found in the dust component (r -6 Esub(S)

Outreach in southern France

International Nuclear Information System (INIS)

Jackson, D.

1992-01-01

France's Europort South community lives cheek by jowl with the chemical industry, with major complexes at For, Berre, and Lavera. Xavier Segond, technical adviser at the regional chemical industry association, Le Syndicat General des Industries Chimiques Provence-Alpes-Cote d'Azur Corse (SGIC), says a good relationship has grown over a period of 20 years. Segond describes Arco Chimie as an effective driving force for the Responsible Care effort in the region - partly because its US parent introduced the program on a worldwide basis in 1989, ahead of national industry association Union des Industries Chimiques (UIC; Paris). Arco's F2-billion ($373 million)/year Fos-sur-Mer site makes it a significant player. But in 1986 the company was a complete newcomer. We came to Fos as a US company, we had no Paris headquarters or French president, explains Dominique Lequeux, director/human resources. The community viewed the company with a mixture of curiosity and enthusiasm as a potential employer - about 330 people now work at the site. The day before the officials propylene oxide plant opening, we invited in local people, says Lequeux. That formed a good basis for its Responsible Care community outreach program. Now, schools, professional groups, and political groups make 20-25 plant visits each year

Paris INDCs: will they achieve the goal of the Paris Climate Agreement?

Science.gov (United States)

Tribett, W. R.; Salawitch, R. J.; Hope, A. P.; Bennett, B.; Canty, T. P.

2016-12-01

We provide an overview of the Intended Nationally Determined Contributions (INDCs) submitted prior to the 21st meeting of the Conference of the Parties to the United Nations Framework Convention on Climate Change, which are the backbone of the Paris Climate Agreement. Two flavors of INDCs were submitted: unconditional (i.e., firm commitments) and conditional (commitments contingent on financial flow and/or technology transfer). Generally, the Paris INDCs extend to year 2030. However, achievement of either the target (1.5 °C warming) or upper limit (2.0 °C warming) of the Paris Agreement requires consideration of emissions out to 2060, due to the projected rise in energy demand, growing populations, and rising standards of living. We therefore project global carbon emissions out to year 2060, and compare to various RCP scenarios of IPCC (2013). These projections will be used to assess whether the target (1.5 °C warming) or upper limit (2.0 °) of the Paris Climate Agreement will be met.

Long-term hydrodynamic response induced by past climatic and geo-morphologic forcing: The case of the Paris basin, France

International Nuclear Information System (INIS)

Jost, A.; Violette, S.; Goncalves, J.; Ledoux, E.; Guyomard, Y.; Guillocheau, F.; Kageyama, M.; Ramstein, G.; Suc, J.P.

2007-01-01

In the framework of safe underground storage of radioactive waste in low-permeability layers, it is essential to evaluate the mobility of deep groundwaters over timescales of several million years. On these timescales, the environmental evolution of a repository should depend upon a range of natural processes that are primarily driven by climate and geo-morphologic variations. In this paper, the response of the Paris basin groundwater system to variations in its hydrodynamic boundary conditions induced by past climate and geodynamic changes over the last five million years is investigated. A three-dimensional transient modelling of the Paris basin aquifer/aquitard system was developed using the code NEWSAM (Ecole des Mines de Paris, ENSMP). The geometry and hydrodynamic parameters of the model originate from a basin model, NEWBAS (ENSMP), built to simulate the geological history of the basin. Geo-morphologic evolution is deduced from digital elevation model analysis, which allows to estimate river-valley incision and alpine uplift. Climate forcing results from paleo-climate modelling experiments using the LMDz atmospheric general circulation model (Institut Pierre Simon Laplace) with a refined spatial resolution, for the present, the Last Glacial Maximum (21 ka) and the Middle Pliocene Warmth (similar to 3 Ma). The water balance is computed by the distributed hydrological model MODSUR (ENSMP). Results about the simulated evolution of piezometric heads in the system in response to the altered boundary conditions are presented, in particular in the vicinity of ANDRA's Bure potential repository site within the Callovo-Oxfordian argillaceous layer. For the present, the comparison of head patterns between steady state and time dependent simulation shows little differences for aquifer layers close to the surface but suggests a transient state of the current system in the main aquitards of the basin and in the deep aquifers, characterized by abnormally low fluid

Dynamic of HIV-testing after arrival in France for migrants from sub-Saharan Africa: The role of both health and social care systems.

Science.gov (United States)

Limousi, Frédérike; Lert, France; Desgrées du Loû, Annabel; Dray-Spira, Rosemary; Lydié, Nathalie

2017-01-01

HIV testing is an important tool in the management of the HIV epidemic among key populations. We aimed to explore the dynamic of first-time HIV testing in France for sub-Saharan migrants after their arrival. ANRS-Parcours is a retrospective life-event survey conducted from 2012 to 2013 in healthcare facilities in the Paris region, among 926 sub-Saharan HIV-infected migrants and 763 non-infected migrants. After describing the time to first HIV test in France and associated circumstances, we performed a discrete-time logistic regression to analyze the influence of socioeconomic position, contact with the healthcare system and sexual behaviors, on first-time HIV testing in France in migrants who arrived after 2000. Median first-time HIV testing occurred during the second year spent in France for non-infected men and women in both groups, and during the first year for men of the HIV group. The probability of testing increased with hospitalization and pregnancy for women of both groups. For non-infected men unemployment and absence of a residence permit were associated with an increased probability of HIV testing [respectively, OR = 2.2 (1.2-4.1) and OR = 2.0 (1.1-3.5)]. Unemployment was also associated with an increased probability of first-time HIV-testing for women of the HIV group [OR: 1.7 (1.0-2.7)]. Occasional and multiple sexual relationships were associated with an increased probability of first-time testing only for HIV-infected women [OR: 2.2 (1.2-4.0) and OR = 2.4 (1.3-4.6)]. Access to first HIV testing in France is promoted by contact with the health care system and is facilitated for unemployed and undocumented migrants after arrival.However, testing should be offered more systematically and repeated in order to reduce time between HIV infection and diagnosis, especially for deprived people which are particularly vulnerable regarding HIV infection.

FOREWORD: 3rd International Workshop on New Computational Methods for Inverse Problems (NCMIP 2013)

Science.gov (United States)

Blanc-Féraud, Laure; Joubert, Pierre-Yves

2013-10-01

aspects of inversion, Bayesian estimation, kernel methods, learning methods, convex optimization, free discontinuity problems, metamodels, proper orthogonal decomposition, reduced models for the inversion, non-linear inverse scattering, image reconstruction and restoration, and applications (bio-medical imaging, non-destructive evaluation...). NCMIP 2013 was a one-day workshop held in May 2013 which attracted around 60 attendees. Each of the submitted papers has been reviewed by three reviewers. Among the accepted papers, there are seven oral presentations, five posters and one invited poster (On a deconvolution challenge presented by C Vonesch from EPFL, Switzerland). In addition, three international speakers were invited to present a longer talk. The workshop was supported by Institut Farman (ENS Cachan, CNRS) and endorsed by the following French research networks (GDR ISIS, GDR Ondes, GDR MOA, GDR MSPC). The program committee acknowledges the following research laboratories CMLA, LMT, LSV, LURPA, SATIE. Laure Blanc-Féraud and Pierre-Yves Joubert Workshop co-chair Laure Blanc-Féraud, I3S laboratory and INRIA Nice Sophia-Antipolis, France Pierre-Yves Joubert, IEF, Paris-Sud University, CNRS, France Technical program committee Gilles Aubert, J-A Dieudonné Laboratory, CNRS and University of Nice-Sophia Antipolis, France Nabil Anwer, LURPA, ENS Cachan, France Alexandre Baussard, ENSTA Bretagne, Lab-STICC, France Marc Bonnet, ENSTA, ParisTech, France Antonin Chambolle, CMAP, Ecole Polytechnique, CNRS, France Oliver Dorn, School of Mathematics, University of Manchester, UK Cécile Durieu, SATIE, ENS Cachan, CNRS, France Gérard Favier, I3S Laboratory, University of Nice Sophia-Antipolis, France Mário Figueiredo, Instituto Superior Técnico, Lisbon, Portugal Laurent Fribourg, LSV, ENS Cachan, CNRS, France Marc Lambert, L2S Laboratory, CNRS, SupElec, Paris-Sud University, France Dominique Lesselier, L2S Laboratory, CNRS, SupElec, Paris-Sud University, France Matteo

How to change West-African minds in order to increase general ...

African Journals Online (AJOL)

EB

), Garches, 92380. Garches, France. 2. Laboratory of Medical Ethics and Forensic Medicine, University of Paris 5, 75006 Paris, France. 3. Department of Pathology, University Hospital, Parakou, Benin. African Health Sciences 2013; 13(2): 526 ...

Review: Hérodote: Revue de géographie et de géopolitique, 2011/3, no. 142: Géopolitique du Sahara, Paris: La Découverte Besprechung: Hérodote: Revue de géographie et de géopolitique, 2011/3, Nr. 142: Géopolitique du Sahara, Paris: La Découverte

Directory of Open Access Journals (Sweden)

Laurence Marfaing

2011-01-01

Full Text Available Review of the issue 2011/3, no. 142, of Hérodote: Revue de géographie et de géopolitique: Géopolitique du Sahara, Paris: La Découverte.Besprechung der Ausgabe 2011/3, Nr. 142, von Hérodote: Revue de géographie et de géopolitique: Géopolitique du Sahara, Paris: La Découverte.

Hauts-de-France. A pioneer in the French energy transition; Hauts-de-France. Vorreiter in der franzoesischen Energiewende

Energy Technology Data Exchange (ETDEWEB)

Falk, Thomas

2016-08-15

France had established in advance of last year's climate summit in Paris on ambitious energy policy goals. Especially the 2016 newly formed Region Hauts-de-France stands out as a pioneer here. There one drives innovation and investments with the objective of fulfilling by 2050 their own needs completely by renewable sources. The orientation to supplies Jeremy Rifkin idea of the third industrial revolution. If successful, the region would be on climate protection well ahead of the national targets, the 2050 ''only'' provide a CO{sub 2} emission reduction of 75%. In addition to the Research and development (R and D) to many future ideas in Hauts-de-France but also some major projects for Security of European energy supplies are realized that show the local agility. [German] Frankreich hatte sich im Vorfeld des letztjaehrigen Pariser-Klimagipfels auf ambitionierte Energiewendeziele festgelegt. Insbesondere die 2016 neu gebildete Region Hauts-de-France sticht dabei als Vorreiter heraus. Dort treibt man Innovationen und Investitionen mit dem Ziel an, bis 2050 den Eigenbedarf vollstaendig mittels erneuerbarer Quellen zu decken. Die Orientierung dazu liefert Jeremy Rifkins Idee der dritten industriellen Revolution. Im Erfolgsfall laege die Region beim Klimaschutz deutlich vor den nationalen Zielen, die bis 2050 ''nur'' eine CO{sub 2}-Emissionsreduktion von 75 % vorsehen. Neben der Forschung und Entwicklung (F and E) zu vielen Zukunftsideen werden in Hauts-de-France aber auch einige Grossprojekte zur Absicherung der europaeischen Energieversorgung realisiert, die Ausweis der dortigen Agilitaet sind.

Phthalates and alkylphenols in industrial and domestic effluents: case of Paris conurbation (France).

Science.gov (United States)

Bergé, A; Gasperi, J; Rocher, V; Gras, L; Coursimault, A; Moilleron, R

2014-08-01

Phthalates and alkylphenols are toxics classified as endocrine disrupting compounds (EDCs). They are of particular concern due to their ubiquity and generally higher levels found in the environment comparatively to other EDCs. Industrial and domestic discharges might affect the quality of receiving waters by discharging organic matter and contaminants through treated waters and combined sewer overflows. Historically, industrial discharges are often considered as the principal vector of pollution in urban areas. If this observation was true in the past for some contaminants, no current data are today available to compare the quality of industrial and domestic discharges as regards EDCs. In this context, a total of 45 domestic samples as well as 101 industrial samples were collected from different sites, including 14 residential and 33 industrial facilities. This study focuses more specifically on 4 phthalates and 2 alkylphenols, among the most commonly studied congeners. A particular attention was also given to routine wastewater quality parameters. For most substances, wastewaters from the different sites were heavily contaminated; they display concentrations up to 1200 μg/l for di-(2-ethylhexyl) phthalate and between 10 and 100 μg/l for diethyl phthalate and nonylphenol. Overall, for the majority of compounds, the industrial contribution to the flux of contaminant reaching the wastewater treatment plants ranges between 1 and 3%. The data generated during this work constitutes one of the first studies conducted in Europe on industrial fluxes for a variety of sectors of activity. The study of the wastewater contribution was used to better predict the industrial and domestic contributions at the scale of a huge conurbation heavily urbanized but with a weak industrial cover, illustrated by Paris. Our results indicate that specific investigations on domestic discharges are necessary in order to reduce the release of phthalates and alkylphenols in the sewer systems

Remediation of context-processing deficits in schizophrenia: preliminary data with ambiguous sentences

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Besche-Richard C

2014-12-01

Full Text Available Chrystel Besche-Richard,1,2 Sarah Terrien,1 Marion Lesgourgues,3,4 Célia Béchiri-Payet,5 Fabien Gierski,1,3 Frédéric Limosin6–8 1Laboratory Cognition, Santé, Socialisation, University of Reims Champagne-Ardenne, France; 2Institut Universitaire de France, Paris, France; 3Centre Hospitalier Universitaire, Pôle de Psychiatrie des Adultes, Reims, France; 4Service Universitaire de Médecine Préventive et de Promotion de la Santé, University of Reims Champagne-Ardenne, Reims, France; 5Etablissement Public de Santé mentale départemental de l’Aisne, Prémontré, France; 6Department of Adult and Geriatric Psychiatry, Hôpitaux Universitaires Paris, Ouest (Assistance publique-Hôpitaux de Paris, Hôpital Corentin-Celton, Issy-les-Moulineaux, France; 7Faculty of Medicine, University Paris Descartes, Sorbonne Paris Cité, Paris, France; 8Psychiatry and Neurosciences Center, French National Institute of Health and Medical Research, Institut National de la Santé et de la Recherche Médicale U894, Paris, France Background: Processing of contextual information is essential for the establishment of good interpersonal relations and communicational interactions. Nevertheless, it is known that schizophrenic patients present impairments in the processing of contextual information. The aim of this study is to explore the influence of the remediation of context processing in schizophrenic patients. Methods: Thirty-one schizophrenic patients and 28 matched healthy participants were included in this study. All participants were assessed on verbal knowledge (Mill-Hill test and depression intensity (Beck Depression Scale 21 items. Schizophrenic patients were also assessed on thought, language, and communication disorders (Thought, Language and Communication scale. All participants completed a disambiguation task with two different levels of contextualization (high or low context and a context-processing remediation task containing social scenarios that

Protocol to amend the convention of 31st January 1963 supplementary to the Paris convention of 29th July 1960 on third party liability in the field of nuclear energy, as amended by the additional protocol of 28th January 1964, Paris, 16 November 1982

International Nuclear Information System (INIS)

1983-01-01

This Protocol further amends the Convention of 31 January 1963 supplementary to the Paris Convention of 29 July 1960 on Third Party Liability in the Field of Nuclear Energy, concluded between the Federal Republic of Germany, Austria, Belgium, Denmark, Spain, Finland, France, Italy, Luxembourg, Norway, Netherlands, United Kingdom, Sweden and Switzerland, within the framework of the Organisation for Economic Co-operation and Development. (U.K.)

Relationship between blood eosinophils, clinical characteristics, and mortality in patients with COPD

Directory of Open Access Journals (Sweden)

Zysman M

2017-06-01

Full Text Available Maeva Zysman,1 Gaëtan Deslee,2 Denis Caillaud,3 Pascal Chanez,4 Roger Escamilla,5 Isabelle Court-Fortune,6 Pascale Nesme-Meyer,7 Thierry Perez,8 Jean-Louis Paillasseur,9 Christophe Pinet,10 Gilles Jebrak,11 Nicolas Roche,12,* Pierre-Régis Burgel12,* On behalf of the Initiatives BPCO (broncho-pneumopathie chronique obstructive Scientific Committee and Investigators 1Pulmonary Dpt, Nancy, Inserm U955, team 04, Créteil, France; 2Pulmonary Dpt, Maison Blanche University Hospital, INSERM U903, Reims, France; 3Pulmonary Dpt, Gabriel Montpied University Hospital, Auvergne University, Clermont-Ferrand, France; 4Pulmonary Dpt, APHM, INSERM U1077, CNRS UMR 7733 Aix Marseille Université, Marseille, France; 5Pulmonary Dpt, Larrey University Hospital, Toulouse, France; 6Pulmonary Dpt, University Hospital, Saint-Etienne, France; 7Pulmonary Dpt, La Croix Rousse University Hospital, Lyon, France; 8Clinique des Maladies Respiratoires, Albert Calmette University Hospital, Lille, France; 9EFFI-STAT, Paris, France; 10Service de pneumologie, polyclinique Les Fleurs, Ollioules, France; 11Pulmonary Dpt, Bichat Hospital, AP-HP, Paris, France; 12Respiratory and Intensive Care Medicine Dpt, Cochin Hospital, AP-HP and Paris Descartes University (EA2511, Sorbonne Paris Cité, Paris, France *These authors contributed equally to this work Abstract: In patients with COPD, there is controversy regarding the association of blood eosinophil (Eos levels with 1 exacerbation frequency and 2 the effect of inhaled corticosteroids for prevention of exacerbations. To determine whether Eos define subgroups of patients exhibiting attributes of COPD clinical phenotypes, we compared clinical features and mortality rates in COPD patients from the Initiatives BPCO French cohort categorized using different thresholds of blood Eos levels. The following data were collected at inclusion: medical and smoking history, occupational exposures, dyspnea, cough and sputum production, exacerbations

France in the front line for geothermal energy

International Nuclear Information System (INIS)

Richard, Aude; Talpin, Juliette

2016-01-01

A set of articles illustrates that France is among the European leaders in heat networks fed by deep aquifers in sedimentary basins, and will soon possess new types of plants to valorise this hot water. A first article describes the operation principle and the distinction between the different geothermal energy levels (very low, low and medium, high). The still slow but actual development of geothermal energy is commented. It notably concerns local communities and industries, but not yet individuals. A brief focus is proposed on the case of the Aquitaine basin and of Bordeaux, and on the use of geothermal energy to cool the wine. The case of Ferney-Voltaire is then discussed: a whole district will be supplied with probe-based tempered water loops. The interest of the ADEME in geo-cooling is evoked. An article comments the development of a new model of deep geothermal energy developed by France and Germany: a dozen of plants are planned to be built by 2020, and the Ecogi plant in Rittershoffen is a showcase of a first application of fractured rock geothermal technology (the operation is described). A map indicates locations of geothermal search permits which have been awarded for 16 sites in France. An overview is given of various initiatives in Ile-de-France. The case of Geothermie Bouillante plant in Guadeloupe is evoked: it has been purchased by an American group and will multiply its electricity production by a factor 4 by 2025. The two last articles respectively address the need to boost the very low geothermal energy sector, and the use of geothermal energy in cities near Paris (Grigny and Viry-Chatillon) which aim at supplying energy at lower prices, and thus struggle against energy poverty

The oncologic outcome and immediate surgical complications of lipofilling in breast cancer patients: a multicenter study--Milan-Paris-Lyon experience of 646 lipofilling procedures.

Science.gov (United States)

Petit, Jean Yves; Lohsiriwat, Visnu; Clough, Krishna B; Sarfati, Isabelle; Ihrai, Tarik; Rietjens, Mario; Veronesi, Paolo; Rossetto, Fabio; Scevola, Anna; Delay, Emmanuel

2011-08-01

Lipofilling is now performed to improve the breast contour, after both breast-conserving surgery and breast reconstruction. However, injection of fat into a previous tumor site may create a new environment for cancer and adjacent cells. There is also no international agreement regarding lipofilling after breast cancer treatment. The authors included three institutions specializing in both breast cancer treatment and breast reconstruction (European Institute of Oncology, Milan, Italy; Paris Breast Center, Paris, France; and Leon Berard Centre, Lyon, France) for a multicenter study. A collective chart review of all lipofilling procedures after breast cancer treatment was performed. From 2000 to 2010, the authors reviewed 646 lipofilling procedures from 513 patients. There were 370 mastectomy patients and 143 breast-conserving surgery patients. There were 405 patients (78.9 percent) with invasive carcinoma and 108 (21.1 percent) with carcinoma in situ. The average interval between oncologic surgical interventions and lipofilling was 39.7 months. Average follow-up after lipofilling was 19.2 months. The authors observed a complication rate of 2.8 percent (liponecrosis, 2.0 percent). Twelve radiologic images appeared after lipofilling in 119 breast-conserving surgery cases (10.1 percent). The overall oncologic event rate was 5.6 percent (3.6 percent per year). The locoregional event rate was 2.4 percent (1.5 percent per year). Lipofilling after breast cancer treatment leads to a low complication rate and does not affect radiologic follow-up after breast-conserving surgery. A prospective clinical registry including high-volume multicenter data with a long follow-up is warranted to demonstrate the oncologic safety. Until then, lipofilling should be performed in experienced hands, and a cautious oncologic follow-up protocol is advised. Therapeutic, IV [corrected].

[The meetings of the Société de Pharmacie de Paris during troubled periods (1803-1946)].

Science.gov (United States)

Storck, J

1997-01-01

With newly found archives and other already usable documents, it was possible to study the repercussions of several troubled periods in France on the meetings of the Société de Pharmacie de Paris (1803-1946). It seems that only three meetings were cancelled for 143 years. As a matter of fact, the number of attending members decreased widely in the troubled times. Allusions to contemporary events are not scarce in the minutes and have been reported.

France and the Rif War: Lessons from a Forgotten Counterinsurgency War (Northern Morocco - April 1925 - May 1927)

Science.gov (United States)

2010-04-07

Points Histoire , 2009. - Harris, Walter, France, Spain and the Rif. London: Edward Arnold & CO., 1927. Woolman, David, Rebels in the Rif, Abd el...Marmie, Laguerre du Rif(Paris: Points Histoire , 2009), 17. 6 On the youth and education of Abd El Krim see Cow·celle-Labrousse, Laguerre du Rif, 213

An Analysis of Magnesium Alloy AZ31B-H24 for Ballistic Applications

Science.gov (United States)

2007-12-01

CELIUS MATERIAL TEKNIK KARLSKOGA AB L HELLNER S 69180 KARLSKOGA SWEDEN 3 CENTRE D’ETUDES GRAMAT J CAGNOUX C GALLIC J TRANCHET... GRAMAT 46500 FRANCE 1 MINISTRY OF DEFENCE DGA DSP STTC G BRAULT 4 RUE DE LA PORTE D’ISSY 00460 ARMEES F 75015 PARIS FRANCE 1

What Does It Mean to be Central? A Botanical Geography of Paris 1830-1848.

Science.gov (United States)

Hoquet, Thierry

2016-02-01

This paper focuses on the geography of the botanical community in Paris, under the July Monarchy (1830-1848). At that time, the Muséum d'Histoire naturelle (MHN) was at its institutional acme and, under the impulse of François Guizot, its budget was increasing dramatically. However, closer attention to manuscript sources (correspondence, travel diaries) reveals that the botanists of the time favoured other private institutions, located both on the Right and Left Banks of the Seine. The MHN was prestigious for its collections and professors but it was relatively remote from the centre of Paris, and its plant samples were sometimes difficult to access. Several other first-class private herbaria granted liberal access to botanists: those of Jacques Gay, Phillip Barker Webb, and Benjamin Delessert. Thanks to their wealth, these plant amateurs had ownership of historical herbaria consisting of species types alongside rich botanical libraries. Botanists visiting Paris from foreign countries or other provinces of France also spent some time studying less general plant collections, like those of Count Jaubert, or specialized collections, like Montagne's or Léveillé's on cryptogams. Other botanists also enjoyed renown at the time, although they published little, if anything (like Maire). Living in crammed apartments, literally in the middle of their plant samples, these botanists were key nodes in botanical networks, although they had no relation with the prestigious MHN.

Maio de 1968 em Paris: testemunho de um estudante Paris, May 1968: witness of a student

Directory of Open Access Journals (Sweden)

Michel Thiollent

1998-10-01

Full Text Available O objetivo deste artigo é apresentar informações sobre os acontecimentos de maio de 1968 na França e seus desdobramentos na vida universitária e intelectual. Os temas abordados são o contexto da crise universitária, as formas de contestação estudantil do ensino de ciências sociais e economia e as fontes intelectuais do movimento. Com base em documentos inéditos, são descritas diversas experiências de comunicação alternativa, de relacionamento entre estudantes e trabalhadores no decorrer dos acontecimentos, assim como uma tentativa de Universidade Popular no 13° distrito de Paris, de julho a outubro de 1968. São analisados alguns aspectos dos debates e da evolução das ciências sociais e da filosofia pós-68, período marcado pela crise do ideário socialista e pelo crescimento do individualismo.This article aims to present the happenigs occured in France in May 1968 and its consequences in the intelectual and university world. The topics are the context of the university crises, the forms of studants complaint against the teaching of Social Sciences and Economy and the intelectual sources of the movement. Based on unpublished documents, many experiences of alternative communication are described and the relationship between students and employees during the happenning and even an attempt to make a Popular University in the 13rd district of Paris, from July to October 1968, as well. Some aspects of the debates and the evolution of the Social Sciences and the Philosophy post 68 are analised. This period was remarked by the crises of the socialist set of ideas and the growth of the individualism.

Information concerning the tax position of Users and Unpaid Associates in France

CERN Multimedia

HR Department

2006-01-01

Users and Unpaid Associates domiciled in France are liable for tax, under ordinary French law, on the remunerations paid by French institutions employing them. They are therefore required to complete and sign a declaration of income form and send it to their local tax office (centre des impôts), together with the annual certificate issued by CERN in accordance with Article R IV 2.04 of the Staff Regulations (cf. the information from the Legal Service and the HR Department concerning declarations of income for 2005 published above). Users and Unpaid Associates remunerated by a French institution but domiciled in Switzerland are required to complete and sign a declaration of income form and send it to the tax office for non residents: Centre des impôts des non-résidents - 9 rue d'Uzès - 75002 Paris - France. Users and Unpaid Associates residing in France for more than six months in 2005 and remunerated by an institution not established in France must also complete a declaration of income form. In the fi...

Prevalence of pain medication prescriptions in France, Germany, and the UK - a cross-sectional study including 4,270,142 patients.

Science.gov (United States)

Jacob, Louis; Kostev, Karel

2018-01-01

The goal of the present study was to analyze the prevalence of pain medication prescriptions in general practices in France, Germany, and the UK. This study included all patients aged ≥18 years followed in 2016 in general practitioner practices in France, Germany and the UK. The primary outcome was the prevalence of patients receiving prescriptions for pain medications in France, Germany, and the UK in 2016. The following drugs were included in the analysis: anti-inflammatory and antirheumatic products, non-steroids and analgesics including opioids, antimigraine preparations, and other analgesics and antipyretics. Demographic variables included age and gender. This study included 4,270,142 patients. The prevalences of pain medication prescriptions were 57.3% in France, 29.6% in Germany, and 21.7% in the UK. Although this prevalence generally remained consistent between age groups in France (54.3%-60.3%), it increased with age in Germany (18-30 years: 23.8%; >70 years: 35.8%) and in the UK (18-30 years: 9.3%; >70 years: 43.8%). Finally, the prevalence of pain medication prescriptions was higher in women than in men in all three countries. Paracetamol was prescribed to 82.3% and 60.1% of patients receiving pain medication in France and the UK, respectively, whereas ibuprofen was prescribed to 46.5% of individuals in Germany. The prevalence of pain medication prescriptions was higher in France than in Germany and the UK. Further research is needed to gain a better understanding of the differences in the prescription patterns between these three European countries.

Regional indexes for France. Methodology

International Nuclear Information System (INIS)

2006-01-01

According to the U.S. Department of Energy, an estimated 25% of the GNP is affected by weather-related events. The variations in temperature - even small ones - can also have long-lasting effects on the operational results of a company. Among other, the Energy supply sector is sensitive to weather risks: a milder or harsher than usual winter leads to a decrease or increase of energy consumption. The price of electricity on power trading facilities like Powernext is especially sensitive to odd changes in temperatures. Powernext and Meteo-France (the French meteorological agency) have joined expertise in order to promote the use of weather indices in term of decision making or underlying of hedging tools to energy actors, end users from any other sector of activity and specialists of the weather risk hedging. The Powernext Weather indices are made from information collected by Meteo-France's main observation network according to the norms of international meteorology, in areas carefully selected. The gross data are submitted to a thorough review allowing the correction of abnormalities and the reconstitution of missing data. Each index is fashioned to take into account the economic activity in the various regions of the country as represented by each region's population. This demographic information represents a fair approximation of the weight of the regional economic activity. This document presents the calculation methodology of regional weather indexes for France. Each regional index covers an homogenous area in terms of temperature represented by the biggest city. Five reference cities are used to represent the 22 economical regions of France (Paris Orly, Lyon, Marignane, Bordeaux and Strasbourg). (J.S.)

Effect of Paris saponin on antitumor and immune function in U14 ...

African Journals Online (AJOL)

bearing mice, and reduced the serum IL-4 level. The Paris saponin can inhibit U14 cell growth and prolong survival time of mice; it is speculated that the Paris saponin may express its anti-tumor activity by improving the body's immune system.

Moyamoya disease and syndromes: from genetics to clinical management

Directory of Open Access Journals (Sweden)

Guey S

2015-02-01

Full Text Available Stéphanie Guey,1,3 Elisabeth Tournier-Lasserve,1,2 Dominique Hervé,1,3 Manoelle Kossorotoff4 1Inserm UMR-S1161, Université Paris 7 Denis Diderot, Sorbonne Paris Cité, Paris, France; 2AP-HP, Groupe hospitalier Lariboisière-Saint-Louis, Service de génétique neurovasculaire, Paris, France; 3Service de Neurologie, Centre de Référence des maladies Vasculaires Rares du Cerveau et de l'Œil (CERVCO, Groupe Hospitalier Saint-Louis Lariboisière-Fernand Widal, Assistance Publique-Hôpitaux de Paris, Paris, France; 4Pediatric Neurology Department, French Center for Pediatric Stroke, University Hospital Necker-Enfants Malades, AP-HP Assistance publique-Hôpitaux de Paris, Paris, France Abstract: Moyamoya angiopathy is characterized by a progressive stenosis of the terminal portion of the internal carotid arteries and the development of a network of abnormal collateral vessels. This chronic cerebral angiopathy is observed in children and adults. It mainly leads to brain ischemic events in children, and to ischemic and hemorrhagic events in adults. This is a rare condition, with a marked prevalence gradient between Asian countries and Western countries. Two main nosological entities are identified. On the one hand, moyamoya disease corresponds to isolated moyamoya angiopathy, defined as being “idiopathic” according to the Guidelines of the Research Committee on the Pathology and Treatment of Spontaneous Occlusion of the Circle of Willis. This entity is probably multifactorial and polygenic in most patients. On the other hand, moyamoya syndrome is a moyamoya angiopathy associated with an underlying condition and forms a very heterogeneous group with various clinical presentations, various modes of inheritance, and a variable penetrance of the cerebrovascular phenotype. Diagnostic and evaluation techniques rely on magnetic resonance imaging (MRI, magnetic resonance angiography (MRA conventional angiography, and cerebral hemodynamics measurements

Short term respiratory health effects of ambient air pollution: results of the APHEA project in Paris.

OpenAIRE

Dab, W; Medina, S; Quénel, P; Le Moullec, Y; Le Tertre, A; Thelot, B; Monteil, C; Lameloise, P; Pirard, P; Momas, I; Ferry, R; Festy, B

1996-01-01

STUDY OBJECTIVE: To quantify the short term respiratory health effects of ambient air pollution in the Paris area. DESIGN: Time series analysis of daily pollution levels using Poisson regression. SETTING: Paris, 1987-92. MEASUREMENTS AND MAIN RESULTS: Air pollution was monitored by measurement of black smoke (BS) (15 monitoring stations), sulphur dioxide (SO2), nitrogen dioxide (NO2), particulate matter less than 13 microns in diameter (PM13), and ozone (O3) (4 stations). Daily mortality and ...

1088-IJBCS-Article-Genevieve Nguessan

African Journals Online (AJOL)

DR GATSING

2 Université Paris-Sud 11, Faculté de Pharmacie, Châtenay-Malabry, France. 3 INSERM UMR-S 769, Châtenay-Malabry, France. 4Laboratoire de pharmacologie, pharmacie clinique, thérapeutique et physiologie, UFR Sciences. Pharmaceutiques et Biologiques, Université Cocody-Abidjan, République de Côte d'Ivoire.

Protection et valorisation du patrimoine géomorphologique en Île- de-France (Bassin de Paris, France)État des lieux et perspectives

OpenAIRE

Bétard, François

2015-01-01

Reconnu depuis une dizaine d’années seulement, le patrimoine géomorphologique fait l’objet d’une attention accrue de la part des scientifiques et des acteurs du territoire, en raison des menaces grandissantes qui pèsent sur la préservation des reliefs et des paysages, mais aussi compte tenu des potentialités qu’offre la valorisation culturelle et touristique des sites d’intérêt géomorphologique (ou géomorphosites) pour le développement local. En France métropolitaine, la région Île-de-France ...

Paris Offscreen: Chinese Tourists in Cinematic Paris

NARCIS (Netherlands)

Y.-A. O. Dung (Yun-An Olivia); S.L. Reijnders (Stijn)

2013-01-01

markdownabstract__Abstract__ This article examines from a European-Asian perspective the relationship between media representations and the tourist’s imagination. We use the case of Chinese tourists in Paris to investigate how these non-European tourists imagine Europe, and how these imaginations

[Reflection on the psychiatric financial allocation in France].

Science.gov (United States)

Boyer, L; Fond, G; Devictor, B; Samuelian, J-C; Lancon, C; Rouillon, F; Gaillard, R; Zendjidjian, X; Llorca, P-M

2016-08-01

For 25years work has been underway in France for the implementation of an alternative to public financing of health care. In the absence of progress, some regional health agencies are engaged in work related to the reallocation of public finances between psychiatric institutions. We propose a reflection with suggestion on the method proposed by the Provence Alpes Côte d'Azur Regional Health Agency. Without questioning the need for a reallocation of resources between psychiatric institutions, the method proposed here needs to evolve further to be applied in a legitimate and appropriate manner. There is a kind of urgency for a reallocation of resources between psychiatric institutions in France, but it implies a collective thinking and especially the definition of evaluation procedures for the selected models. These conditions are necessary to guarantee the quality of French psychiatry and equity in access to psychiatric care. Copyright © 2016 L’Encéphale, Paris. Published by Elsevier Masson SAS. All rights reserved.

Dietary inadequacies observed in homeless men visiting an emergency night shelter in Paris.

Science.gov (United States)

Darmon, N; Coupel, J; Deheeger, M; Briend, A

2001-04-01

To assess the dietary intake and the nutritional status of homeless men. A night emergency shelter in Paris, France. Dietary survey (48-h) including alcohol intake and a questionnaire on age, duration of homelessness, smoking habits. Subjects were also weighed and measured. Ninety-seven men aged 18-72 years (mean 43.3), of whom 54% were homeless for more than 18 months, 82% were smokers and 53% were regular and/or excessive drinkers. The BMI distribution was shifted towards low values, the percentage of wasted persons being four times higher than in the reference population. The mean total energy intake was 2376 kcal and included a high and highly variable percentage of energy derived from alcohol (12.0% Among drinkers, the mean ethanol intake was 90 g and there was a significant negative correlation between ethanol and non-alcoholic energy intakes. The median intakes of potassium, calcium, zinc, vitamins B1, B2, and niacin were lower than European Population Reference Intakes but only the mean intake of vitamin B1 was significantly lower. Eighty percent of non-alcoholic energy was provided by charitable organisations. For most nutrients, the nutritional density of the shelter ration was not significantly different from the density of the foods purchased by the homeless. These data suggest that the content of some nutrients should be increased in existing food assistance programs for homeless people in France.

Electrical energy statistics for France

International Nuclear Information System (INIS)

2009-07-01

In 2008, national electrical consumption reached 494.5 TWh, an increase of 2.9 % compared with 2007 (480.4 TWh). Adjusted for winter and summer climate contingencies and leap year, its evolution rate compared with 2007 is +1.3 % Consumption by business and private customers came to 198.0 TWh, an increase of 5.9 % compared with 2007 (187.0 TWh); consumption by Large-scale industry and SME/SMIs came to 263.0 TWh, an increase of 0.7 % compared with 2007 (261.3 TWh). Generation in France came to 549.1 TWh, as in 2006, an increase of 4.3 TWh or +0.8 % compared with 2007 (544.8 TWh). Hydro-electric generation reached 68.0 TWh, an increase of 7.5 % compared with 2007 (63.3 TWh). Renewable energy sources generation but hydro reached 9.7 TWh, an increase of 23.8 % compared with 2007 (7.8 TWh), mainly due to an increase of 37.5 % of wind energy (5.6 TWh in 2008 compared with 4.0 TWh in 2007). This progression is coherent with the increase of 48% of the installed capacity for wind generation. Nuclear generation came to 418.3 TWh in 2008, a decrease of 0.1 % compared with 2007 (418.6 TWh). Fossil thermal generation came to 53.1 TWh, a decrease of 3.5 % compared with 2007 (55.1 TWh). The heaviest load in terms of capacity reaches 92.4 GW during winter 2008/2009. Its evolution rate compared with 2007 is +3.8 % with a temperature lower by 2.2 deg. C. Since 2001, the heaviest load in winter has increased by 16% whereas the national electrical consumption has increased by 10%. The year 2008 is marked by the commissioning of the 400 kV line VIGY-MARLENHEIM. Besides, the underground circuits lengths grow by 118 km over the entire network. In terms of physical exchanges of electrical energy between France and the neighbouring countries France exported a net total of 48.0 TWh, a decrease of 15.4 % compared with 2007 (56.7 TWh). Contractual exchanges with foreign countries came to a cumulative value for exports and imports of 116.2 TWh, an increase of 5.1 % compared with 2007 (110.5 TWh

La Cité Universitaire Internationale de Paris

Directory of Open Access Journals (Sweden)

Sébastien Bureau

2008-05-01

Full Text Available La Cité Internationale Universitaire de Paris est le lieu où se concentrent le plus de résidences universitaires en Île-de-France avec une vocation affichée d’accueillir les étudiants et chercheurs du monde entier, et ce depuis 1925. Elle leur offre un ensemble de services centralisés et un cadre privilégié mais se considère avant tout comme un creuset pour la rencontre des cultures et la diffusion de la culture française parmi les élites intellectuelles internationales. Au-delà des intentions, nous avons cherché, par la rencontre de ses dirigeants et des résidents, à saisir d’une part, la réalité actuelle des échanges culturels promus par une politique du « brassage » et d’autre part, la dynamique de « l’espace vécu » des résidents.The Cité Internationale of Paris is the place where concentrate most university halls of residence in the French capital with a displayed vocation to welcome the students and the researchers of the whole world since 1925. It offers to them a set of centralized services and a privileged living environment but considers itself above all as a melting pot for the meeting of cultures and the spreading of French culture among international intellectual elites. Beyond intentions, we tried, by the meeting of managements and residents, to grasp the current reality of cultural exchanges thanks to the policy of the "mixing" and the dynamic of "the space lived" on residents.

Developing solar energy in France

International Nuclear Information System (INIS)

Alary-Grall, L.

2003-01-01

3 years ago the 'Soleil' program was launched and today 660.000 m 2 of solar cells have been installed which has made France to rank 4 behind Germany, Greece and Austria in terms of the use of solar energy. The 'Soleil' program, that will end in 2006, aims at developing solar energy in France and is composed of 4 axis: 1) the contribution to the funding of solar equipment through enticing financial helps, 2) the implementation of a quality plan for the installers of solar equipment, 3) the setting of a quality label for innovative and efficient solar equipment and 4) the promoting of solar energy to the professionals of the construction sector. (A.C.)

Regulation of pluralism in France. Context, analysis and interpretation

Directory of Open Access Journals (Sweden)

Núria Almiron-Roig, Ph.D.

2010-01-01

Full Text Available This article offers a historical and up-to-date study of the media regulation in France with regards to the protection of pluralism. To this end, the article presents a study on the French legal framework for the media, which is complemented with the opinions of scholars, journalists, trade union representatives, members of public organizations regulating the media, and relevant figures with expertise in the media sector in France. The views of these actors were obtained through a series of in-depth interviews conducted in Paris in July 2008 and December 2009. The study reveals that the legal framework, which uses multiple mechanisms and instruments to guarantee pluralism, both external (mainly, corporate concentration and internal (media contents, is highly complex, vast, difficult, and almost impossible to apply. The study suggests that the French legal framework is a top example of inefficient hyper-regulation, which the author sees as a result of the ferocious battle between the two strongest modern forces in France: the egalitarian democratic values, based on solidarity and deeply rooted in the historical tradition of the French Republic; and the neoliberal capitalism based on the ideas of material accumulation and individualism.

France @ CERN | Come and meet 37 French companies at the 2014 “France @ CERN” Event | 1-3 December

CERN Multimedia

2014-01-01

The 13th “France @ CERN” event will take place from 1 December to 3 December 2014. Thanks to Ubifrance, the French agency for international business development, 37 French firms will have the opportunity to showcase their know-how at CERN.   These companies are looking forward to meeting you during the B2B sessions which will be held on Tuesday, 2 December (afternoon) and on Wednesday, 3 December (afternoon) in buildings 500 and 61 or at your convenience in your own office. The fair’s opening ceremony will take place on Tuesday, 2 December (morning) in the Council Chamber in the presence of Rolf Heuer, Director-General of CERN and Nicolas Niemtchinow, Ambassador, Permanent Representative of France to the United Nations in Geneva and to international organisations in Switzerland. For more information about the event and the 37 participating French firms, please visit: http://www.la-france-au-cern.com/

Euro plays : Canadian companies find success in England and France

International Nuclear Information System (INIS)

Marsters, S.

1998-01-01

A growing list of Canadian companies are searching for oil and gas onshore in England and France. Cirque Energy Corp., Vermilion Resources Ltd., Morrison Middlefield Resources Ltd., and Bow Valley Energy Ltd., are among the companies that are taking advantage of the underexplored basins, little competition, availability of land, and (in the case of the United Kingdom) a superior fiscal regime. Cirque Energy Corp. entered the U.K. in 1995 and currently has a 220,000 acre land position in the East Midlands basin, 250 km north of London. The main producing reservoirs are Permo-Carboniferous in age. The geology is similar to that in the North Sea. In November 1998, Cirque plans to build a 2,500 metre, six inch pipeline to transport up to 1,500 gross bbls of oil per day. Vermilion Resources Ltd. acquired oil and gas assets in the Paris and Aquitaine basin. The company has executed a $10.1 million workover and recompletion program on 42 wells which has increased production to more than 6,000 BOE per day from the previous 4,000 BOE per day. 3 figs

[From traditional to modern hospital--from Paris to Berlin].

Science.gov (United States)

Murken, Axel Hinrich

Discussions about the modernisation and reform of the Hôtel Dieu in Paris concerning the catastrophic fire of 1772 there were followed very closely in Prussia and other German countries, though for a long time this had only slight consequences for modernising developments in the hospitals of Berlin or other administrative capitals of Germany. In contrast to this, the Hôpital Lariboisière was praised as a model example in Germany soon after its completion in 1854 after the pre-revolutionary Parisian plans, was imitated in Berlin twenty years later. It must be added that in Prussia great importance was attached to stricter requirements for hygiene and ventilation than in Paris. This was clearly demonstrated barely in the construction of the pavilionhospital in Berlin-Friedrichshain (1868-1874) with an extremely decentralized layout. It was not until two generations later with the completion of the municipal hospital Westend in Charlottenburg (1904-1907), a suburb of Berlin, that a slightly modified "Lariboisière" in the Wilheminian brick Baroque style was built. Similarily the acceptance of high-rise construction was, compared with Paris, considerably delayed on the German hospital scene. Whereas in the USA and France plans had been made for high-rise hospitals from the 1920s on and realized by 1935, as with the Hôpital Beaujon in Paris (1932-1935), there were fundamental reservations about them in Germany. As a result, this conception of the structure, with an effective concentration of inpatient care in towers together with separate low-rise buildings for functions such as treatment and diagnosis, only gradually gained acceptance in Germany at the end of the 1960s. On the other hand, German architects such as Hermann Distel (1875-1946) or Ernst Kopp (1890-1962), had already, indeed before the Second World War, promoted the high-rise type for inpatient care on theoretical grounds. In addition, two hospitals providing medical care within in Berlin, Martin

Nucleaire et Energies Nr 63 - June 2014. 18 months before the Paris Climate Conference

International Nuclear Information System (INIS)

Lenail, Bernard; Ducroux, Guy; Lamorlette, Guy; Seyve, Claude; Simonnet, Jacques; Justin, Francois; Darricau, Aime; Blanc, Jacques; Salanave, Jean-Luc; Raisonnier, Daniele; Deleigne, Francoise

2014-06-01

After a first article which evokes the perspective and challenges of the Paris Climate Conference, two articles address energy issues: a discussion of the evolution of the energy sector (challenge of energy transition, evolutions of the energy mix in different countries, shale gases in the USA, Europe and France, electricity prices in France, situation and projects of French energy companies) and an overview of news in the renewable energy sector (in Morocco, Germany and the UK, the second bidding for offshore wind projects in France). Three articles deal with nuclear energy: agreements and projects in Niger, news about various fuel production sites in different countries, overview of the situation of reactors (EPR, China) and decisions on projects and investments in different countries, overview of activities and events related to the back-end of the fuel cycle (notably in different Areva sites) and to decommissioning in different countries. Four articles address societal issues related to nuclear safety and environment (relationships between French nuclear operators and Safety Authorities, the situation of populations around Fukushima, Greenpeace in Fessenheim, the issue of fuel sheath wear, use of rare earth materials in wind turbines), a positive perception of the presence of Areva (after Cogema) in Niger, a scenario for Fessenheim, and the deep disposal Cigeo project

Understanding the Paris agreement: analysing the reporting requirements under the enhanced transparency framework

DEFF Research Database (Denmark)

Desgain, Denis DR; Sharma, Sudhir

At the Paris climate conference (COP-21) in December 2015, the Conference of the Parties decided to adopt the Paris Agreement under the United Nations Framework Convention on Climate Change. This was the first time that 195 Parties had agreed on a universal, legally binding climate instrument......th October 2016, 74 Par¬ties had ratified the Agreement, accounting for 58.82% of global GHG emissions.1 The Paris Agreement will thus enter into force on 4th November 2016....

Where are the radioactive wastes in France? Brochure no 4; Ou sont les dechets radioactifs en France? Brochure no 4

Energy Technology Data Exchange (ETDEWEB)

NONE

2004-07-01

This document is one of the 6 regional brochures which make the geographical inventory of radioactive wastes in France. For each region, a table lists the recorded sites and a regional map localizes those having a detailed descriptive file. These files mention the most important waste owners (medical, research, nuclear and military industries), the type of waste and the type of management. The polluted sites are also mentioned, even if they are already decontaminated. The volume no 4 concerns the Auvergne and Rhone-Alpes regions. (J.S.)

Wartime Paris, cirrhosis mortality, and the ceteris paribus assumption.

Science.gov (United States)

Fillmore, Kaye Middleton; Roizen, Ron; Farrell, Michael; Kerr, William; Lemmens, Paul

2002-07-01

This article critiques the ceteris paribus assumption, which tacitly sustains the epidemiologic literature's inference that the sharp decline in cirrhosis mortality observed in Paris during the Second World War derived from a sharp constriction in wine consumption. Paris's wartime circumstances deviate substantially from the "all else being equal" assumption, and at least three other hypotheses for the cirrhosis decline may be contemplated. Historical and statistical review. Wartime Paris underwent tumultuous changes. Wine consumption did decline, but there were, as well, a myriad of other changes in diet and life experience, many involving new or heightened hardships, nutritional, experiential, institutional, health and mortality risks. Three competing hypotheses are presented: (1) A fraction of the candidates for cirrhosis mortality may have fallen to more sudden forms of death; (2) alcoholics, heavy drinkers and Paris's clochard subpopulation may have been differentially likely to become removed from the city's wartime population, whether by self-initiated departure, arrest and deportation, or death from other causes, even murder; and (3) there was mismeasurement in the cirrhosis mortality decline. The alcohol-cirrhosis connection provided the template for the alcohol research effort (now more than 20 years old) aimed at re-establishing scientific recognition of alcohol's direct alcohol-problems-generating associations and causal responsibilities. In a time given to reports of weaker associations of the alcohol-cirrhosis connection, the place and importance of the Paris curve in the wider literature, as regards that connection, remains. For this reason, the Paris findings should be subjected to as much research scrutiny as they undoubtedly deserve.

Relative humidity impact on aerosol parameters in a Paris suburban area

Directory of Open Access Journals (Sweden)

H. Randriamiarisoa

2006-01-01

Full Text Available Measurements of relative humidity (RH and aerosol parameters (scattering cross section, size distributions and chemical composition, performed in ambient atmospheric conditions, have been used to study the influence of relative humidity on aerosol properties. The data were acquired in a suburban area south of Paris, between 18 and 24 July 2000, in the framework of the 'Etude et Simulation de la Qualité de l'air en Ile-de-France' (ESQUIF program. According to the origin of the air masses arriving over the Paris area, the aerosol hygroscopicity is more or less pronounced. The aerosol chemical composition data were used as input of a thermodynamic model to simulate the variation of the aerosol water mass content with ambient RH and to determine the main inorganic salt compounds. The coupling of observations and modelling reveals the presence of deliquescence processes with hysteresis phenomenon in the hygroscopic growth cycle. Based on the Hänel model, parameterisations of the scattering cross section, the modal radius of the accumulation mode of the size distribution and the aerosol water mass content, as a function of increasing RH, have been assessed. For the first time, a crosscheck of these parameterisations has been performed and shows that the hygroscopic behaviour of the accumulation mode can be coherently characterized by combined optical, size distribution and chemical measurements.

Rayleigh lidar observations of double stratopause structure over three different northern hemisphere stations

CSIR Research Space (South Africa)

Sivakumar, V

2006-09-01

Full Text Available observations of double stratopause structure over three different northern hemisphere stations V. Sivakumar1, H. Bencherif1, A. Hauchecorne2, P. Keckhut2, D. N. Rao3, S. Sharma4, H. Chandra4, A. Jayaraman4, and P. B. Rao5 1Laboratoire de l’Atmosphe`re et... des Cyclones, CNRS–UMR 8105, Universite´ de La Re´union, La Reunion, France 2Service d’Ae´ronomie, CNRS, Paris, France 3National Atmospheric Research Laboratory, P. B. No: 123, Tirupati-517 502, India 4Physical Research Laboratory, Navarangapura...

The Applicability of Patented Technologies to Sonobuoys

Science.gov (United States)

1988-06-30

Ave, Boulder, CO 80301 2. Compagnie Generale de Geophysique 6 Rue Galvani Paris, France 3. EIC Laboratories, Incorporated Newton, MA 02146 4. Edo...Co. 2 Compagnie de Geophysique , France 3 Cooper, Charles E. 2 M Crown Controls Corporation 1 ,6 Cyr, Reginald J. 1 DeltaLab Research, Incorporated 1...Int’l App ....... 7,5 [73) Assignees: Institut Francais du Petrole. OTHER PUBLICATIONS -" Rueil-Malmaison; Compagnie Generale de Geophysique , Massy

Christophe Couderc, dir., Le théâtre Espagnol du Siècle d'Or en France. De la traduction au transfert culturel

Directory of Open Access Journals (Sweden)

Christian Andrès

2012-12-01

Full Text Available Review of Christophe Couderc, Le théâtre Espagnol du Siècle d'Or en France. De la traduction au transfert culturel, Presses Universitaires de Paris Ouest, París, 2012, 299 pp. ISBN: 978-2-84016-102-8.

Water circulation control on carbonate-δ18O records in a low permeability clay formation and surrounding limestones: The Upper Dogger-Oxfordian sequence from the eastern Paris basin, France

International Nuclear Information System (INIS)

Lavastre, Veronique; Ader, Magali; Buschaert, Stephane; Petit, Eddy; Javoy, Marc

2011-01-01

Research highlights: → Up. Dog./Oxf. sequence is investigated for radioactive waste disposal feasibilities. → Marine carbonates suffered isotopic exchanges with meteoric water. → Modelling shows that very low W/R ratio can explain isotopic changes in clay layer. → Higher W/R ratio are needed to reach isotopic changes in carbonated layers. → Confirmed barrier property of clay layer was probably reached during early burial. - Abstract: Upper Dogger to Oxfordian Formations in the eastern part of the Paris basin (France) are currently being investigated by the French nuclear waste management agency (Andra), testing the feasibility of long-term deep nuclear waste disposal in the Callovo-Oxfordian claystones. Characterising the hydrogeological behaviour of the Callovo-Oxfordian claystones is, therefore, essential in evaluating its potential as a geological barrier. In order to evaluate and quantify water/rock interactions experienced over geological time by these Formations, bulk carbonate δ 13 C and δ 18 O were measured and calculations of water-rock ratios were used to explain carbonate-δ 18 O changes. Meteoric porewater and a maximum temperature reached of about 40 deg. C were considered. The Jurassic marine carbonate δ 13 C was preserved in the Callovo-Oxfordian claystones and in the overlying limestones (-0.28 per mille to 3.39 per mille/PDB), while the δ 18 O values are lower by 0-5 per mille (-6.25 per mille to -1.32 per mille/PDB). Calculations show that Upper Dogger and Oxfordian Limestone δ 18 O data: (i)have random-like distribution through theoretical δ 18 O-W/R curves and (ii)suggest that water/rock ratios (0.08-0.4) needed to explain δ 18 O changes are higher by a factor of about 2-20 compared to the present-day water/rock ratio. These features indicate advection in both aquifers. According to the history of the Paris basin, this hydrogeological behaviour could have been effective since Jurassic/Cretaceous transition times. Inversely, the

Considering the Creation of a Domestic Intelligence Agency in the United States: Lessons from the Experiences of Australia, Canada, France, Germany, and the United Kingdom

Science.gov (United States)

2009-01-01

National Infrastructure. CSIS—see Canadian Security Intelligence Service. Dard, Olivier, “L’OAS: Histoire d’un Refus,” Guerre d’Algérie, Vol. 8, June...Faligot, Jean Guisnel, and Rémi Kauffer, eds., Histoire Secrète de la Ve République, Paris: La Découverte, 2006a, pp. 394–399. ———, “La France Complice...ou Otage de la Seconde Guerre d’Algérie?” in Roger Faligot, Jean Guisnel, and Rémi Kauffer, eds., Histoire Secrète de la Ve République, Paris: La

The Paris Observatory has 350 years

Science.gov (United States)

Lequeux, James

2017-01-01

The Paris Observatory is the oldest astronomical observatory that has worked without interruption since its foundation to the present day. The building due to Claude Perrault is still in existence with few modifications, but of course other buildings have been added all along the centuries for housing new instruments and laboratories. In particular, a large dome has been built on the terrace in 1847, with a 38-cm diameter telescope completed in 1857: both are still visible. The main initial purpose of the Observatory was to determine longitudes. This was achieved by Jean-Dominique Cassini using the eclipses of the satellites of Jupiter: a much better map of France was the produced using this method, which unfortunately does not work at sea. Incidentally, the observation of these eclipses led to the discovery in 1676 of the finite velocity of light by Cassini and Rømer. Cassini also discovered the differential rotation of Jupiter and four satellites of Saturn. Then, geodesy was to be the main activity of the Observatory for more than a century, culminating in the famous Cassini map of France completed around 1790. During the first half of the 19th century, under François Arago, the Observatory was at the centre of French physics, which then developed very rapidly. Arago initiated astrophysics in 1810 by showing that the Sun and stars are made of incandescent gas. In 1854, the new director, Urbain Le Verrier, put emphasis on astrometry and celestial mechanics, discovering in particular the anomalous advance of the perihelion of Mercury, which was later to be a proof of General Relativity. In 1858, Leon Foucault built the first modern reflecting telescopes with their silvered glass mirror. Le Verrier created on his side modern meteorology, including some primitive forecasts. The following period was not so bright, due to the enormous project of the Carte du Ciel, which took much of the forces of the Observatory for half a century with little scientific return. In

Is Individual Metering Socially Sustainable? The Case of Multifamily Housing in France

Directory of Open Access Journals (Sweden)

Bernard Barraqué

2011-06-01

Full Text Available Before generalising water metering and billing at the apartment level for consumer equity reasons, and alleviating the burden of water bills for poor families through increasing block tariffs (IBTs, Paris Council asked for some expert advice. The pros and cons of two separate issues – IBTs efficiency and justice; and individual household metering – were mixed. Our research first summarises various studies of the redistributive effects of tariff changes, first from flat rates to metering, and then from uniform prices to IBTs. We address the particular case of multifamily housing, where it is possible to retain collective billing, while relying on sub-metering to allocate the bill. The limitations of classical econometric surveys on large samples (in terms of understanding households’ strategies with tap water support the need for supplementary detailed sociological surveys at neighbourhood or building levels, if only to check the unexpected redistributive effects of tariff changes in practice. We review the specific French situation, peculiarly in Paris, to show that individual apartment billing is more costly and tends to have regressive effects. Like other cities in France, Paris abandoned the implementation of Art. 93 of the 2000 law, which encouraged individual billing; and we explain why.

In depth analysis of urban accidents involving motorcycle and moped riders in France, construction of prototypical accident scenarios and prospects for their prevention. Poster

OpenAIRE

CLABAUX, N

2007-01-01

in France, in 2006, in spite of a low part of travel, motorcycle and moped riders accounted for 23% of all traffic fatalities and 31% of all injuries recorded. This extra risk is particularly marked in urban areas and in large cities. According to national accident statistics, in urban areas, accidents involving motorcycles and mopeds account for 20% and 23,6% respectively, of all injury accidents recorded. In the city of Paris, in 2005, powered two-wheelers accounted for 3% of all travel but...

SUMOylation of the KRAB zinc-finger transcription factor PARIS/ZNF746 regulates its transcriptional activity

International Nuclear Information System (INIS)

Nishida, Tamotsu; Yamada, Yoshiji

2016-01-01

Parkin-interacting substrate (PARIS), a member of the family of Krüppel-associated box (KRAB)-containing zinc-finger transcription factors, is a substrate of the ubiquitin E3 ligase parkin. PARIS represses the expression of peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α), although the underlying mechanisms remain largely unknown. In the present study, we demonstrate that PARIS can be SUMOylated, and its SUMOylation plays a role in the repression of PGC-1a promoter activity. Protein inhibitor of activated STAT y (PIASy) was identified as an interacting protein of PARIS and shown to enhance its SUMOylation. PIASy repressed PGC-1a promoter activity, and this effect was attenuated by PARIS in a manner dependent on its SUMOylation status. Co-expression of SUMO-1 with PIASy completely repressed PGC-1a promoter activity independently of PARIS expression. PARIS-mediated PGC-1a promoter repression depended on the activity of histone deacetylases (HDAC), whereas PIASy repressed the PGC-1a promoter in an HDAC-independent manner. Taken together, these results suggest that PARIS and PIASy modulate PGC-1a gene transcription through distinct molecular mechanisms. -- Highlights: •PARIS can be SUMOylated in vivo and in vitro. •SUMOylation of PARIS functions in the repression of PGC-1a promoter activity. •PIASy interacts with PARIS and enhances its SUMOylation. •PIASy influences PARIS-mediated repression of PGC-1a promoter activity.

SUMOylation of the KRAB zinc-finger transcription factor PARIS/ZNF746 regulates its transcriptional activity

Energy Technology Data Exchange (ETDEWEB)

Nishida, Tamotsu, E-mail: nishida@gene.mie-u.ac.jp; Yamada, Yoshiji

2016-05-13

Parkin-interacting substrate (PARIS), a member of the family of Krüppel-associated box (KRAB)-containing zinc-finger transcription factors, is a substrate of the ubiquitin E3 ligase parkin. PARIS represses the expression of peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α), although the underlying mechanisms remain largely unknown. In the present study, we demonstrate that PARIS can be SUMOylated, and its SUMOylation plays a role in the repression of PGC-1a promoter activity. Protein inhibitor of activated STAT y (PIASy) was identified as an interacting protein of PARIS and shown to enhance its SUMOylation. PIASy repressed PGC-1a promoter activity, and this effect was attenuated by PARIS in a manner dependent on its SUMOylation status. Co-expression of SUMO-1 with PIASy completely repressed PGC-1a promoter activity independently of PARIS expression. PARIS-mediated PGC-1a promoter repression depended on the activity of histone deacetylases (HDAC), whereas PIASy repressed the PGC-1a promoter in an HDAC-independent manner. Taken together, these results suggest that PARIS and PIASy modulate PGC-1a gene transcription through distinct molecular mechanisms. -- Highlights: •PARIS can be SUMOylated in vivo and in vitro. •SUMOylation of PARIS functions in the repression of PGC-1a promoter activity. •PIASy interacts with PARIS and enhances its SUMOylation. •PIASy influences PARIS-mediated repression of PGC-1a promoter activity.

Journal of Biosciences | Indian Academy of Sciences

Indian Academy of Sciences (India)

4. Faculté de Pharmacie, 27, Boulevard Jean Moulin, 13385 Marseille, France; CNRS Délégation Régionale Languedoc-Roussillon, 34293 Montpellier, France; Faculté de Médecine Xavier -Bichat, 75870 Paris, France; Institut de Biologie ...

Via Lyon: Parcours de romans et mutations éditoriales au XVIe siècle. Partie II. La circulation des textes entre Lyon et Paris

Directory of Open Access Journals (Sweden)

Gaëlle Burg

2015-07-01

Full Text Available La première partie du dossier Via Lyon (Carte Romanze 2/2 [2014] analysait le rôle de carrefour économique et culturel de la ville de Lyon dans la constitution d’une identité éditoriale des romans publiés en France au XVIe siècle. L’étude de ces «parcours de romans» conduit à replacer, en cette seconde partie du dossier, la notion d’«étape lyonnaise» dans la dynamique qui anime les deux principaux centres d’imprimerie français de la Renaissance. L’étude des pérégrinations éditoriales, de Paris à Lyon et de Lyon à Paris, de Lancelot du Lac (G. Burg, de Valentin et Orson (M. Colombo Timelli et de Méliadus chevalier de la Croix (A. Réach-Ngô met ainsi au jour les diverses formes de circulation, d’adaptation et de réappropriation que les ateliers parisiens et lyonnais confèrent aux œuvres romanesques qui passent sous leurs presses tout au long du siècle. The first part of the file Via Lyon (Carte Romanze 2/2 [2014] analyzed the role of economic and cultural crossroad of Lyon city in the constitution of an editorial identity of novels published in France in the sixteenth century. The study of these «novels’ route» leads to situate the concept of «Lyon step» in the dynamics which animates the two major French printing centers of the Renaissance. The editorial peregrinations, from Paris to Lyon and from Lyon to Paris, of three french novels, Lancelot du Lac (G. Burg, Valentin and Orson (M. Colombo Timelli and Méliadus chevalier de la Croix (A. Réach-Ngô, shows the various forms of circulation, adaptation and reappropriation that various Parisian and Lyon workshops give to novels they print throughout the century. 

Small-area spatiotemporal analysis of heatwave impacts on elderly mortality in Paris: A cluster analysis approach.

Science.gov (United States)

Benmarhnia, Tarik; Kihal-Talantikite, Wahida; Ragettli, Martina S; Deguen, Séverine

2017-08-15

Heat-waves have a substantial public health burden. Understanding spatial heterogeneity at a fine spatial scale in relation to heat and related mortality is central to target interventions towards vulnerable communities. To determine the spatial variability of heat-wave-related mortality risk among elderly in Paris, France at the census block level. We also aimed to assess area-level social and environmental determinants of high mortality risk within Paris. We used daily mortality data from 2004 to 2009 among people aged >65 at the French census block level within Paris. We used two heat wave days' definitions that were compared to non-heat wave days. A Bernoulli cluster analysis method was applied to identify high risk clusters of mortality during heat waves. We performed random effects meta-regression analyses to investigate factors associated with the magnitude of the mortality risk. The spatial approach revealed a spatial aggregation of death cases during heat wave days. We found that small scale chronic PM 10 exposure was associated with a 0.02 (95% CI: 0.001; 0.045) increase of the risk of dying during a heat wave episode. We also found a positive association with the percentage of foreigners and the percentage of labor force, while the proportion of elderly people living in the neighborhood was negatively associated. We also found that green space density had a protective effect and inversely that the density of constructed feature increased the risk of dying during a heat wave episode. We showed that a spatial variation in terms of heat-related vulnerability exists within Paris and that it can be explained by some contextual factors. This study can be useful for designing interventions targeting more vulnerable areas and reduce the burden of heat waves. Copyright © 2017 Elsevier B.V. All rights reserved.

Gaz de France 2006 annual report; Gaz de France 2006 rapport d'activite

Energy Technology Data Exchange (ETDEWEB)

NONE

2006-07-01

Gaz de France is major European energy utility, which produces, purchases, transports, distributes and sells natural gas, electricity and related services for its residential, corporate and local government customers. Its strategic focuses are to develop an ambitious marketing strategy, pursue a supply and procurement policy that guarantees the Group's competitiveness, confirm its position as a benchmark infrastructure manager, and speed up its profitable growth in Europe. Gaz de France aligns its strategy with a concrete and ambitious sustainable development policy. Its growth model is based on responsiveness to customers and constructive dialogue with its employees and partners. This document is the activity report of the group for the year 2006. It presents: 1 - the corporate profile of the group; 2 - its strategies (energy, energy supply, infrastructures); 3 - its financial highlights; 4 - its governance, shareholders and human resources; 5 - the activities of the group (exploration and production, energy procurement, energy sales, services, transmission France, storage France, LNG terminals, distribution France, transmission and distribution international, research and development); 6 - its 2006 financial data and financial summary.

Louis-Eugène Varlin e a Comuna de Paris (1871

Directory of Open Access Journals (Sweden)

João Alberto da Costa Pinto

2011-03-01

Full Text Available O artigo propõe uma breve notícia sobre a trajetória política de Louis-Eugène Varlin (1839 - 1871, operário francês (encadernador de livros radicado em Paris (1852 - 1871, intelectual autodidata, um dos principais organizadores da seção francesa da AIT (Associação Internacional dos Trabalhadores a partir de 1865. Personagem emblemático nas lutas sociais acontecidas no período de setembro de 1870 a maio de 1871, quando do cerco à cidade pelas tropas prussianas e depois pelas tropas do governo Thiers, motivos que o levaram à participação no Comitê Central da Guarda Nacional, assim como à organização dos comitês distritais da Comuna (março a maio de 1871.     

Interaction between different groundwaters in brittany catchments (france): characterizing multiple sources through Sr- and S isotope tracing

Science.gov (United States)

Negrel, Ph; Pauwels, H.

2003-04-01

Water resources in hard-rocks commonly involve different hydrogeological compartments such as overlying sediments, weathered rock, the weathered-fissured zone, and fractured bedrock. Streams, lakes and wetlands that drain such environments can drain groundwater, recharge groundwater, or do both. Groundwater resources in many countries are increasingly threatened by growing demand, wasteful use, and contamination. Surface water and shallow groundwater are particularly vulnerable to pollution, while deeper resources are more protected from contamination. Sr- and S-isotope data as well as major ions, from shallow and deep groundwater in three granite and Brioverian "schist" areas of the Armorican Massif (NW France) with intensive agriculture covering large parts are presented. The stable-isotope signatures of the waters plot close to the general meteoric-water line, reflecting a meteoric origin and the lack of significant evaporation or water-rock interaction. The water chemistry from the different catchments shows large variation in the major-element contents. Plotting Na, Mg, NO_3, K, SO_4 and Sr vs. Cl contents concentrations reflect agricultural input from hog and livestock farming and fertilizer applications, with local sewage-effluent influence, although some water samples are clearly unpolluted. The δ34S(SO_4) is controlled by several potential sources (atmospheric sulphate, pyrite-derived sulphates, fertilizer sulphates). Some δ18O and δ34S values are expected to increase through sulphate reduction, with higher effect on δ34S for the dissimilatory processes and on δ18O for assimilatory processes. The range in Sr contents in groundwater from different catchments agrees with previous work on groundwater sampled from granites in France. The Sr content is well correlated with Mg and both are related to agricultural practises. As in granite-gneiss watersheds in France, 87Sr/86Sr ratios range from 0.71265 to 0.72009. The relationship between 87Sr/86Sr and Mg

[Involuntary psychiatric care for inmates in France: Only for "dangerous" patients?

Science.gov (United States)

Fovet, T; Bertrand, M; Horn, M; Si Mohammed, W; Dandelot, D; Dalle, M-C; Thomas, P; Amad, A

2017-11-27

The unités hospitalières spécialement aménagées (UHSA) are full-time inpatient psychiatric units for inmates in France. Their creation has been associated with several advances in access to psychiatric care for inmates in recent years. However, there is still only one means of involuntary hospitalization for prisoners in France: care by decision of a representative of the state (les soins sur décision d'un représentant de l'état [SDRE]). Interestingly, for SDRE to be recognized as legal by the French judge, the patient must be "a danger to himself or to the others". Thus, there is a major difference with involuntary hospitalization outside the prison, and there are specific criteria for involuntary psychiatric hospitalization for inmates in France. This situation questions the general framework of involuntary psychiatric care and is very inconsistent with French law. Indeed, the goal of the loi n o  94-43 du 18 janvier 1994 relating to public health and social protection is to ensure equivalent care for all patients, incarcerated or not. Copyright © 2017 L'Encéphale, Paris. Published by Elsevier Masson SAS. All rights reserved.

Robustness of Electrical Systems of Nuclear Power Plants in Light of the Fukushima Daiichi Accident (ROBELSYS). Workshop Proceedings, Paris, France, 1-4 April 2014. Appendix 2 (Cont'd) and Appendix 3 - Robustness of Electrical Systems of NPP's in Light of the Fukushima Daiichi Accident. ROBELSYS Workshop Proceedings. Appendices 2 and 3

International Nuclear Information System (INIS)

2015-01-01

The March 2011 accident at Fukushima Daiichi triggered discussions about the significance of electrical power hazards and their treatment in safety analyses. In order to address these issues and provide relevant conclusions and recommendations to CSNI and CNRA, the Robustness in Electrical Systems (ROBELSYS) Technical Working Group was established in 2012 under the leadership of the Institut de Radioprotection et de Surete Nucleaire (IRSN) of France. The purpose of the ROBELSYS Technical Working Group was to organize an international workshop to identify and discuss the lessons learned from the Fukushima Daiichi accident. The workshop was focused on the provisions taken by various countries concerning national requirements and modifications to the plant designs in order to enhance the robustness of electrical systems, especially the protection against extreme external hazards. The ROBELSYS workshop was held at the OECD Conference Centre in Paris in April 1-4, 2014. A total of 105 participants attended the workshop representing industry and government organisations from 25 countries, as well as international organisations. A total of 34 technical presentations were given in seven sessions as follows: - 1: National Programmes on Evolution of Onsite and Offsite Electric Power Systems; - 2: Role of Electric Power in Severe Accident Management; - 3: Requirements for Robustness of Onsite Electric Power Systems; - 4: Simulation of Transients within NPP Plant Distribution Systems; - 5: Requirements for Equipment Used for Emergency Response; - 6: Margin Assessments for Modern Power Electronics; - 7: Digital Components in Power Systems. Items addressed in the workshop included: - Review of the lessons learned from the Fukushima accident concerning the robustness of electrical systems; - Review of the provisions already taken or planned after the Fukushima accident, regarding the sources, the distribution systems and the loads, and documenting the technical basis for these

Water circulation control on carbonate-{delta}{sup 18}O records in a low permeability clay formation and surrounding limestones: The Upper Dogger-Oxfordian sequence from the eastern Paris basin, France

Energy Technology Data Exchange (ETDEWEB)

Lavastre, Veronique, E-mail: veronique.lavastre@univ-st-etienne.fr [Universite de Lyon, Universite Jean Monnet, F-42023 Saint Etienne (France)] [CNRS, UMR 6524, LMV, F-42023 Saint Etienne (France)] [Laboratoire de Geochimie des Isotopes Stables, Institut de Physique du Globe de Paris and Universite Paris 7 - UMR CNRS 7154, 4, place Jussieu, 75252 Paris cedex 05 (France); Ader, Magali [Laboratoire de Geochimie des Isotopes Stables, Institut de Physique du Globe de Paris and Universite Paris 7 - UMR CNRS 7154, 4, place Jussieu, 75252 Paris cedex 05 (France); Buschaert, Stephane [Andra, Parc de la Croix Blanche, 7-8 rue Jean Monnet, 92 298 Chatenay-Malabry Cedex (France); Petit, Eddy; Javoy, Marc [Laboratoire de Geochimie des Isotopes Stables, Institut de Physique du Globe de Paris and Universite Paris 7 - UMR CNRS 7154, 4, place Jussieu, 75252 Paris cedex 05 (France)

2011-05-15

Research Highlights: > Up. Dog./Oxf. sequence is investigated for radioactive waste disposal feasibilities. > Marine carbonates suffered isotopic exchanges with meteoric water. > Modelling shows that very low W/R ratio can explain isotopic changes in clay layer. > Higher W/R ratio are needed to reach isotopic changes in carbonated layers. > Confirmed barrier property of clay layer was probably reached during early burial. - Abstract: Upper Dogger to Oxfordian Formations in the eastern part of the Paris basin (France) are currently being investigated by the French nuclear waste management agency (Andra), testing the feasibility of long-term deep nuclear waste disposal in the Callovo-Oxfordian claystones. Characterising the hydrogeological behaviour of the Callovo-Oxfordian claystones is, therefore, essential in evaluating its potential as a geological barrier. In order to evaluate and quantify water/rock interactions experienced over geological time by these Formations, bulk carbonate {delta}{sup 13}C and {delta}{sup 18}O were measured and calculations of water-rock ratios were used to explain carbonate-{delta}{sup 18}O changes. Meteoric porewater and a maximum temperature reached of about 40 deg. C were considered. The Jurassic marine carbonate {delta}{sup 13}C was preserved in the Callovo-Oxfordian claystones and in the overlying limestones (-0.28 per mille to 3.39 per mille/PDB), while the {delta}{sup 18}O values are lower by 0-5 per mille (-6.25 per mille to -1.32 per mille/PDB). Calculations show that Upper Dogger and Oxfordian Limestone {delta}{sup 18}O data: (i)have random-like distribution through theoretical {delta}{sup 18}O-W/R curves and (ii)suggest that water/rock ratios (0.08-0.4) needed to explain {delta}{sup 18}O changes are higher by a factor of about 2-20 compared to the present-day water/rock ratio. These features indicate advection in both aquifers. According to the history of the Paris basin, this hydrogeological behaviour could have been

Importance of data comparability for multi-year trends and source apportionment of NMHC concentrations observed in France

Science.gov (United States)

Sauvage, Stéphane; Waked, Antoine; Leonardis, Thierry; Locoge, Nadine

2017-04-01

Non Methane Hydrocarbon Compounds (NMHCs) are of interest due to their potential health impact and their key role in atmospheric processes as precursors of secondary pollutants such as ozone (O3) and secondary organic aerosols (SOA). Hourly measurements of 31 non-methane hydrocarbons (NMHCs) were carried out at three urban sites in France over the period of a decade. The trends analysis showed a significant yearly decrease in pollutant concentrations over the study period and for the majority of species in the range of -1 to -7% in accordance with the decrease of NMHC emissions in France (-5 to -9%). Concentrations of long-lived species such as ethane and propane which are known as tracers of distant sources and natural gas remained constant. These trends are consistent with those recently described at urban and background sites in the northern mid-latitudes and with emission inventories. They are compared with the ones reported for 3 French rural sites (EMEP). A year per year source apportionment study using PMF was also conducted for 2 of the urban sites over the period 2005-2013. Using source fingerprints, five common anthropogenic sources were identified for Paris and Strasbourg: traffic-exhaust emissions (21±5%, 18±5%), evaporative sources (17±4%, 24±7%), natural gas & background (22±5%, 25±5%), residential heating (17±4%, 17±5%) and solvent use (19±7%, 12±5%). Biogenic sources were also identified and accounted for 4±1% of the total measured NMHC's at both sites. Along the presentation, the robustness of these results will be discussed regarding the site representativeness, the data comparability, and the temporal variation of the data quality

FOREWORD: 2nd International Workshop on New Computational Methods for Inverse Problems (NCMIP 2012)

Science.gov (United States)

Blanc-Féraud, Laure; Joubert, Pierre-Yves

2012-09-01

, reduced models for the inversion, non-linear inverse scattering, image reconstruction and restoration, applications (bio-medical imaging, non-destructive evaluation etc). NCMIP 2012 was a one-day workshop. Each of the submitted papers was reviewed by 2 to 4 reviewers. Among the accepted papers, there are 8 oral presentations and 5 posters. Three international speakers were invited for a long talk. This second edition attracted 60 registered attendees in May 2012. NCMIP 2012 was supported by Institut Farman (ENS Cachan) and endorsed by the following French research networks (GDR ISIS, GDR Ondes, GDR MOA, GDR MSPC). The program committee acknowledges the following laboratories CMLA, LMT, LSV, LURPA, SATIE, as well as DIGITEO Network. Laure Blanc-Féraud and Pierre-Yves Joubert Workshop Co-chairs Laure Blanc-Féraud, I3S laboratory, CNRS, France Pierre-Yves Joubert, IEF laboratory, Paris-Sud University, CNRS, France Technical Program Committee Alexandre Baussard, ENSTA Bretagne, Lab-STICC, France Marc Bonnet, ENSTA, ParisTech, France Jerôme Darbon, CMLA, ENS Cachan, CNRS, France Oliver Dorn, School of Mathematics, University of Manchester, UK Mário Figueiredo, Instituto Superior Técnico, Lisbon, Portugal Laurent Fribourg, LSV, ENS Cachan, CNRS, France Marc Lambert, L2S Laboratory, CNRS, SupElec, Paris-Sud University, France Anthony Quinn, Trinity College, Dublin, Ireland Christian Rey, LMT, ENS Cachan, CNRS, France Joachim Weickert, Saarland University, Germany Local Chair Alejandro Mottini, Morpheme group I3S-INRIA Sophie Abriet, SATIE, ENS Cachan, CNRS, France Béatrice Bacquet, SATIE, ENS Cachan, CNRS, France Reviewers Gilles Aubert, J-A Dieudonné Laboratory, CNRS and University of Nice-Sophia Antipolis, France Alexandre Baussard, ENSTA Bretagne, Lab-STICC, France Laure Blanc-Féraud, I3S laboratory, CNRS, France Marc Bonnet, ENSTA, ParisTech, France Jerôme Darbon, CMLA, ENS Cachan, CNRS, France Oliver Dorn, School of Mathematics, University of Manchester, UK G�

Supervisory Control of Multiple Uninhabited Systems - Methodologies and Enabling Human-Robot Interface Technologies (Commande et surveillance de multiples systemes sans pilote - Methodologies et technologies habilitantes d’interfaces homme-machine)

Science.gov (United States)

2012-12-01

FRANCE 6.1 DATES SMAART (2006 – 2008) and SUSIE (2009 – 2011). 6.2 LOCATION Brest – Nancy – Paris (France). 6.3 SCENARIO/TASKS The setting...Agency (RTA), a dedicated staff with its headquarters in Neuilly, near Paris , France. In order to facilitate contacts with the military users and...Mission Delay for the Helicopter 8-12 Table 8-2 Assistant Interventions and Commander’s Reactions 8-13 Table 10-1 Partial LOA Matrix as Originally

Electrical Energy Statistics for France 2002; Statistiques de l'energie electrique en France - 2002

Energy Technology Data Exchange (ETDEWEB)

NONE

2003-11-01

Detailed statistics on electricity flows in France and on facilities. Regional data / Consumption per sector of activity / Records over last 10 years (definitive results). In 2002, national electrical consumption reached 449.9 TWh, an increase of 0.3% compared with 2001 (448.6 TWh). Adjusted for winter and summer climate contingencies, its growth rate was 0.9% compared with 2001. Consumption by customers connected at high or medium voltage levels came to 254.2 TWh, an increase of 0.8% compared with 2001 (252.3 TWh); consumption by customers connected at low voltage levels came to 165 TWh, a decrease of 0.8% compared with 2001 (166.4 TWh). Generation in France reached 534.3 TWh, an increase of 11.5 TWh or 2.2% compared with 2001 (522.8 TWh). This increase broke down between nuclear generation and conventional thermal generation. Net nuclear generation injected, as measured by RTE, came to 415.5 TWh in 2002, an increase of 4.0% compared with 2001 (399.6 TWh). Conventional thermal generation came to 51.1 TWh, an increase of 15.4 % compared with 2001 (44.3 TWh). Hydro-electric generation amounted to 65.5 TWh, a fall of 15.3% compared with 2001 (77.3 TWh). In terms of physical exchanges with foreign countries, France exported a net total of 77 TWh, an increase of 12.6% compared with 2001 (68.4 TWh). Contractual exchanges with foreign countries, recorded by RTE, fell by 9.9 % to reach a cumulative value for exports and imports of 107.8 TWh (compared with 120 TWh in 2001)

[Legionnaires disease : 3 cases from the northern suburbs of Paris (author's transl)].

Science.gov (United States)

Valeyre, D; Dournon, E; Jeantils, V; Kemeny, J L; Blin, F; Battesti, J P

1981-01-01

During the summer of 1980, 3 sporadic cases of Legionnaires disease (ML) were recognized in the northern suburbs of Paris. The clinical picture was characterized by an extensive pneumonia, high fever with repeated rigors (3 cases), a confusional state (2 cases), and transitory watery diarrhea (3 cases). Blood cultures, evidence of bacterial antigens in blood or urine, and serology notably for chlamydia and mycoplasma pneumoniae were all negative. The diagnosis of ML (serotype I) was confirmed by serology using indirect immunofluorescence against Legionella pneumophila (LP) with an antigen prepared by Taylor. In one patient treated early with erythromycin (4 g/day), there was a quick and favorable response. Two other patients died, and in their case erythromycin therapy was started late. At necropsy, the lesions were solely thoracic, and were characterized by an alveolitis with many macrophages, and intense leukocytosis, and rich in fibrin; in one case, extensive fibrosis was noted; in the other, LP was diagnosed by direct and indirect immunofluorescence on a lung specimen. In the pneumology department of Hôpital Avicenne, two other patients with acute pneumonias and similar clinical and radiological pictures had elevated titres to LP (1/64), but they did not rise or fall. The diagnosis of ML is probably nevertheless, particularly as the serology was negative for both Mycoplasma pneumoniae and the Chlamydias. Two of the three cases presented were among seventeen acute febrile pneumonias admitted to the pneumology department of Hôpital Avicenne between the 1st of July and the 1st of October 1980, showing the relative frequency of this infection.

Neighbourhood Characteristics and Long-Term Air Pollution Levels Modify the Association between the Short-Term Nitrogen Dioxide Concentrations and All-Cause Mortality in Paris.

Science.gov (United States)

Deguen, Séverine; Petit, Claire; Delbarre, Angélique; Kihal, Wahida; Padilla, Cindy; Benmarhnia, Tarik; Lapostolle, Annabelle; Chauvin, Pierre; Zmirou-Navier, Denis

2015-01-01

While a great number of papers have been published on the short-term effects of air pollution on mortality, few have tried to assess whether this association varies according to the neighbourhood socioeconomic level and long-term ambient air concentrations measured at the place of residence. We explored the effect modification of 1) socioeconomic status, 2) long-term NO2 ambient air concentrations, and 3) both combined, on the association between short-term exposure to NO2 and all-cause mortality in Paris (France). A time-stratified case-crossover analysis was performed to evaluate the effect of short-term NO2 variations on mortality, based on 79,107 deaths having occurred among subjects aged over 35 years, from 2004 to 2009, in the city of Paris. Simple and double interactions were statistically tested in order to analyse effect modification by neighbourhood characteristics on the association between mortality and short-term NO2 exposure. The data was estimated at the census block scale (n=866). The mean of the NO2 concentrations during the five days prior to deaths were associated with an increased risk of all-cause mortality: overall Excess Risk (ER) was 0.94% (95%CI=[0.08;1.80]. A higher risk was revealed for subjects living in the most deprived census blocks in comparison with higher socioeconomic level areas (ER=3.14% (95%CI=[1.41-4.90], ppollution episodes. There is also an indication that people living in these disadvantaged census blocks might experience even higher risk following short-term air pollution episodes, when they are also chronically exposed to higher NO2 levels.

Chemical characteristics of saponins from Paris fargesii var. brevipetala and cytotoxic activity of its main ingredient, paris saponin H.

Science.gov (United States)

Wen, Feiyan; Yin, Hongxiang; Chen, Chu; Liu, Xianbo; Xue, Dan; Chen, Tiezhu; He, Jun; Zhang, Hao

2012-06-01

More attention was paid to the anti-tumor activity of Rhizoma Paridis (RP) recently, of which the wild resource was decreased significantly. This study was aimed to elucidate the chemical characteristics of Paris fargesii var. brevipetala (PFB) that may be administrated as alternate resource of legal RP. A HPLC-ELSD method was established to characterize the steroid saponins in rhizomes of PFB and two legal Paris species [Paris polyphylla var. chinensis (PPC) and P. polyphylla var. yunnanensis (PPY)] in Chinese Pharmacopoeia (CP). Ten saponins (paris saponins I, II, V, VI, VII, H, gracillin and other three paris saponins) were involved as standards. The results indicated that PFB contained pennogenyl saponins as the main components with small amounts of diosgenin saponins. The total contents of the detected saponins in PFB ranged from 9.12mg/g to 85.33mg/g. Nine of the twelve PFB samples own a total content of paris saponins I, II, VI, and VII more than 6.0mg/g (meeting the standard of CP 2010 edition). Principal Component Analysis (PCA) and Partial Least Squares-Discriminate Analysis (PLS-DA) both confirmed the fact that saponin profiles of PFB, PPC and PPY were different from each other. In addition, paris saponin H (Ps H), the predominant saponin of PFB (>50%), was tested in vitro to evaluate its cytotoxic activities on HepG2, A549, RPE and L929 cells with a positive control of Cisplatin. Ps H showed a remarkable cytotoxic activity on A549 cells with an IC(50) value of 1.53±0.08μg/mL. Copyright © 2012 Elsevier B.V. All rights reserved.

MDEP Conference on New Reactor Design Activities - Multinational Design Evaluation Programme (MDEP) Conference Proceedings, Paris, France, 10-11 September 2009

International Nuclear Information System (INIS)

2010-01-01

The MDEP is a unique ten-nation initiative being undertaken by national regulatory authorities from Canada, China, Finland, France, Japan, Republic of Korea, the Russian Federation, South Africa, the United Kingdom, and the United States with the purposes of co-operating on safety design reviews of new reactors and identifying opportunities to harmonise and converge on safety licensing review practices and requirements. The OECD Nuclear Energy Agency has been chosen to provide the technical secretariat support. The International Atomic Energy Agency participates in many of the MDEP activities. Started in 2007 with co-operation on various pilot project issues, the MDEP's expected outcomes are: (1) improved effectiveness and efficiency of regulatory safety design reviews, (2) increased quality of safety assessments, and (3) and identified areas for the convergence of regulatory requirements and practices. Making each regulator stronger in its ability to make sovereign safety decisions is a key objective that cuts across all MDEP activities. In 2008, the top regulators from each national authority met as the MDEP Policy Group and adopted the present structure and programme of work for the MDEP, including the pursuit of co-operation on specific safety design reviews and pursuing closer co-ordination on harmonisation and convergence issues such as digital instrumentation and control, mechanical codes and standards, and vendor inspections. The MDEP is currently a long-term programme that focuses in near term and interim results to share within MDEP and with other stakeholders. With effective communications in mind, the MDEP Policy Group directed the NEA to co-ordinate the Conference on New Reactor Design Activities with the purpose of communicating to a wide spectrum of stakeholders worldwide as to the program of work and accomplishments of the MDEP, and soliciting feedback and input from these stakeholders regarding recommendations on how to co-operate more efficiently

Learning from CDM SD tool experience for Article 6.4 in the Paris Agreement

DEFF Research Database (Denmark)

Olsen, Karen Holm; Arens, Christof; Mersmann, Florian

2017-01-01

The Paris Agreement (PA) emphasizes the intrinsic relationship between climate change and sustainable development (SD) and welcomes the 2030 agenda for the global Sustainable Development Goals (SDGs). Yet, there is a lack of assessment approaches to ensure that climate and development goals...

The chemical industry of uranium in France; L'industrie chimique de l'uranium en France

Energy Technology Data Exchange (ETDEWEB)

Goldschmidt, B [Commissariat a l' Energie Atomique, Paris (France). Centre d' Etudes Nucleaires

1955-07-01

The actual CEA program is concerned with the construction of two large graphite reactors, each of those containing at least one hundred tons of uranium metal with nuclear purity. The uranium for these two reactors will be regularly supplied by new resources discovered in France and Madagascar in the last five years. The working and treatment of such ore have led to the creation of an important french industry of which the general outline and principle are described. The operated ores have got different natures and concentration, individual characteristics are described for the main ores.The most high-grade ore are transported to a central plant in Bouchet near Paris; the low-grade ore are concentrated by physical methods or chemical processes of which principles and economy are studied with constancy. The acid processes are the only used until now, although the carbonated alkaline processes has been studied in France. The next following steps after the acid process until the obtention of uranium rich concentrate are described. The purification steps of uranium compounds to nuclear purity material are described as well as the steps to elaborate metal of which the purity grade will be specify. Finally, the economic aspects of uranium production difficulty will be considered in relation with technical progresses which we can expect to achieve in the future. (M.P.)

Social mix policies in Paris: discourses, policies and social effects.

Science.gov (United States)

Bacqué, Marie-Hélène; Fijalkow, Yankel; Launay, Lydie; Vermeersch, Stéphanie

2011-01-01

Since the 1980s, the issue of social mix has become a public policy category in France. Enshrined in legislation, yet remaining controversial, it represents a major premise on which housing policies have been reconfigured. The concept of social mix is essentially based on who lives where, but it is also evoked in the context of urban renewal schemes for social housing estates, as well as in relation to new-build developments. A study of the bases of social mix policies conducted in Paris since 2001 in the context of the embourgeoisement of the capital shows the fundamental role of social housing stock. The City Council has become involved in policy decisions about both the location and the allocation of social housing. Particular attention has been paid to the middle classes in the name of the principle of ‘balancing the population’. In order to measure the effects of the policy, this article relies on an analysis of two City of Paris schemes that have the stated intent of creating social mix. One of these schemes consists of redeveloping a working-class neighbourhood, Goutte d'Or, while the other involves the new acquisition of social housing in various more affluent neighbourhoods in the capital. This comparative study of the population shows that, whether in a neighbourhood poised for gentrification or in a more affluent neighbourhood, this policy has major effects on forms of local social cohesion, setting in motion individual trajectories and reshaping social and/or ethnic identities.

[Are therapeutics decisions homogeneous in multidisciplinary onco-urology staff meeting? Comparison of therapeutic options taken in four departments from Paris].

Science.gov (United States)

Audenet, F; Lejay, V; Mejean, A; De La Taille, A; Abbou, C-C; Lebret, T; Botto, H; Bitker, M-O; Roupret, M

2012-06-01

One of the priorities of the "Plan against the Cancer" in France is to ensure the discussion of all cancer cases in a multidisciplinary meeting staff (RCP). The multidisciplinary collaboration is proposed to guarantee a discussion between specialists in every cases, particularly in complex cases. The aim of this study was to compare the therapeutic decision taken in four RCP in Paris Île-de-France academic centres for three identical cases. Three cases of urological oncology (prostate cancer [PCa], renal cell carcinoma [RCC] and bladder tumour) were selected by a single urologist, not involved in further discussion. These cases were blindly presented in four academic urology department from Paris: Pitié-Salpêtrière Hospital, Mondor Hospital, the Georges-Pompidou European Hospital and Foch Hospital. The four centres met the criteria of quality of RCP in terms of multidisciplinarity, frequency and standardization. The therapeutic suggestions were similar in the RCC cases, there were differences in the surgical approaches and preoperative work-up in the PCa case and, lastly, the proposals were different for the bladder cancer case. The decisions relies on clinical data and preoperative work-up but also on the experience and habits of the centre of excellence. For complex cases that does not fit with current guidelines, the panel discussion can lead to different therapeutic options from a centre to another and is largely influenced by the local organisation of the RCP. Copyright © 2012 Elsevier Masson SAS. All rights reserved.

Lack of reliable alternatives means France faces challenges finding a replacement for nuclear

Energy Technology Data Exchange (ETDEWEB)

Dalton, David [NucNet, Brussels (Belgium)

2017-03-15

The lack of alternative low-carbon energy sources that are as reliable as nuclear means France's ''ambitious'' plans to reduce its share of nuclear from 78 % in 2015 to 50 % by 2025 might not be achievable, the International Energy Agency (IEA) said in its January 2017 report. The Paris-based agency said France - which has the world's highest share of nuclear in its electricity mix - must assess possible changes in energy demand and supply and to guarantee ''continuous security of electricity supply'' as it pushes ahead with its plans for an ''energy transition'' up to 2050. The Energy Transition for Green Growth Act (Loi relative a la transition energetique pour la croissance verte, LTECV) was the result of consultations that ran from January to July 2013.

Climate Justice and the Paris Agreement

International Nuclear Information System (INIS)

Michelot, Agnes

2016-01-01

The concept of climate justice has been, for the first time, used in an international agreement - namely, the Paris Agreement. But this recognition of the notion of climate justice is extremely restricted by the very way it is formulated. Preamble of the Paris Agreement 'notes' that climate justice is recognized by 'certain cultures'. Does it mean that particular and concrete stakes of climate justice of the pre-COP21 agenda have been recognized or, on the contrary, that the notion so introduced is actually an empty shell without any genuine legal perspective? Considering this uncertainty, it appears relevant to analyze the Paris Agreement through the claims of various groups and coalitions, which influenced the COP21 negotiations

Neighbourhood Characteristics and Long-Term Air Pollution Levels Modify the Association between the Short-Term Nitrogen Dioxide Concentrations and All-Cause Mortality in Paris.

Directory of Open Access Journals (Sweden)

Séverine Deguen

Full Text Available While a great number of papers have been published on the short-term effects of air pollution on mortality, few have tried to assess whether this association varies according to the neighbourhood socioeconomic level and long-term ambient air concentrations measured at the place of residence. We explored the effect modification of 1 socioeconomic status, 2 long-term NO2 ambient air concentrations, and 3 both combined, on the association between short-term exposure to NO2 and all-cause mortality in Paris (France.A time-stratified case-crossover analysis was performed to evaluate the effect of short-term NO2 variations on mortality, based on 79,107 deaths having occurred among subjects aged over 35 years, from 2004 to 2009, in the city of Paris. Simple and double interactions were statistically tested in order to analyse effect modification by neighbourhood characteristics on the association between mortality and short-term NO2 exposure. The data was estimated at the census block scale (n=866.The mean of the NO2 concentrations during the five days prior to deaths were associated with an increased risk of all-cause mortality: overall Excess Risk (ER was 0.94% (95%CI=[0.08;1.80]. A higher risk was revealed for subjects living in the most deprived census blocks in comparison with higher socioeconomic level areas (ER=3.14% (95%CI=[1.41-4.90], p<0.001. Among these deprived census blocks, excess risk was even higher where long-term average NO2 concentrations were above 55.8 μg/m3 (the top tercile of distribution: ER=4.84% (95%CI=[1.56;8.24], p for interaction=0.02.Our results show that people living in census blocks characterized by low socioeconomic status are more vulnerable to air pollution episodes. There is also an indication that people living in these disadvantaged census blocks might experience even higher risk following short-term air pollution episodes, when they are also chronically exposed to higher NO2 levels.

Organic market gardening around the Paris agglomeration: agro-environmental performance and capacity to meet urban requirements.

Science.gov (United States)

Anglade, Juliette; Medina, Michael Ramos; Billen, Gilles; Garnier, Josette

2016-05-04

Organic market gardening is often promoted by urban municipalities as a way to resource part of the food supply, creating new social links and protecting groundwater resources. The agronomical and environmental performance of six commercial organic market gardening farms supplying vegetables in Paris were evaluated and compared with other vegetable production systems. When expressed in terms of protein production, the yield of these systems appears rather low compared with the productive capacity of open-field organic cropping systems where vegetable production is inserted into rotation with other crops. Moreover, the requirement of producing infiltrated water meeting the drinking water standards seriously limits the allowable rate of fertilisation, thus limiting production. The data reported herein show that to supply the amount of vegetables required by the Paris agglomeration (12 million inhabitants) only by organic market gardening, 160,000-205,000 ha, i.e. 28-36 % of the agricultural area of the surrounding Ile-de-France region, would be required. We conclude that organic market gardening is only one of several other farming systems which can contribute to a re-localised supply of vegetables to large cities.

パリの日本人学校における文化背景の異なる生徒をめぐって

OpenAIRE

大森, 康宏; オオモリ, ヤスヒロ; Yasuhiro, Omori

1982-01-01

In the Japanese School in Paris, France, three groups ofpupils, distinguished by their different overseas experience, areenrolled; (1) those who came to France directly from Japan;(2) those who were formerly enrolled in the French school system;and (3) pupils who had lived in another country after leavingJapan and before going to France.This paper attempts to describe the main socio-culturalproblems found among the three groups at the only Japaneseschool in Paris, as a consequence of their di...

Determinants and consequences of insulin initiation for type 2 diabetes in France: analysis of the National Health and Wellness Survey

Directory of Open Access Journals (Sweden)

Reach G

2013-10-01

Full Text Available Gérard Reach,1 Véronique Le Pautremat,2 Shaloo Gupta31Department of Endocrinology, Diabetes, and Metabolic Diseases, Avicenne Hospital APHP, and EA 3412, CRNH-IdF, Paris 13 University, Sorbonnne Paris Cité, Bobigny, France; 2Kantar Health, Paris, France; 3Kantar Health, Princeton, NJ, USABackground: The aim of the study was to identify the intrinsic patient characteristics and extrinsic environmental factors predicting prescription and use and, more specifically, early initiation (up to 5 years of disease duration of insulin for type 2 diabetes in France. A secondary objective was to evaluate the impact of insulin therapy on mental and physical quality of life and patient adherence.Methods: The data used in this study were derived from the 2008, 2010, and 2011 France National Health and Wellness Survey. This survey is an annual, cross-sectional, self-administered, Internet-based questionnaire among a nationwide representative sample of adults (aged 18 years or older. Of the total of 45,958 persons recruited in France, 1,933 respondents (deduped were identified as diagnosed with type 2 diabetes. All unique respondents from the three waves, currently using insulin or oral bitherapy or tritherapy at the time of assessment, were included in this analysis.Results: Early (versus late initiation of insulin therapy was 9.9 times more likely to be prescribed by an endocrinologist or diabetologist than by a primary care physician (P < 0.0001. Younger age at diagnosis and current smoking habits were significant predictors of early (versus late insulin initiation (odds ratio [OR] 1.031, 95% confidence interval [CI] 1.005–1.059, P = 0.0196, and OR 2.537, 95% CI 1.165–5.524, P = 0.0191, respectively. Patients with a yearly income ≥€50,000 were less likely to be put on insulin early (P = 0.0399. A link between insulin prescription and complications was shown only in univariate analysis. Mental quality of life was lower in patients on early (versus

Localising the nitrogen imprint of the Paris food supply: the potential of organic farming and changes in human diet

Science.gov (United States)

Billen, G.; Garnier, J.; Thieu, V.; Silvestre, M.; Barles, S.; Chatzimpiros, P.

2012-01-01

The Seine watershed has long been the food-supplying hinterland of Paris, providing most of the animal and vegetal protein consumed in the city. Nowadays, the shift from manure-based to synthetic nitrogen fertilisation, has made possible a strong land specialisation of agriculture in the Seine watershed: it still provides most of the cereal consumed by the Paris agglomeration, but exports 80% of its huge cereal production. On the other hand the meat and milk supply originates mainly from regions in the North and West of France, specialised in animal farming and importing about 30% of their feed from South America. As it works today, this system is responsible for a severe nitrate contamination of surface and groundwater resources. Herein two scenarios of re-localising Paris's food supply are explored, based on organic farming and local provision of animal feed. We show that for the Seine watershed it is technically possible to design an agricultural system able to provide all the plant- and animal-based food required by the population, to deliver sub-root water meeting the drinking water standards and still to export a significant proportion of its production to areas less suitable for cereal cultivation. Decreasing the share of animal products in the human diet has a strong impact on the nitrogen imprint of urban food supply.

The Callovo-Oxfordian of the Paris Basin: From its geological context to the modelling of its properties; Le Callovo-Oxfordien du bassin de Paris: du contexte geologique a la modelisation de ses proprietes

Energy Technology Data Exchange (ETDEWEB)

Anon

2006-10-15

The French law from December 30, 1991 entrusted the French national agency for radioactive wastes (ANDRA) with the mission of assessing the feasibility of a deep geological repository in the clay-rich Callovo-Oxfordian formation of NE France (Meuse and Haute-Marne departements). A research program, coordinated by ANDRA and involving several university laboratories and other French organizations (CNRS, CEA, BRGM, INERIS, INPL, ENSMP) has permitted to gather a huge amount of information about the properties of the Callovo-Oxfordian formation of the eastern part of the Paris basin. These properties are summarized in this introductive paper: paleo-geography, bio-stratigraphy of ammonites, clay mineralogy and other minerals content, anisotropy of argillite beds, permeability and porosity, osmosis and thermal diffusion, chemistry of interstitial waters, fracturing.. (J.S.)

What agreement in Paris in 2015?

International Nuclear Information System (INIS)

Colombier, Michel; Ribera, Teresa

2015-01-01

In Warsaw, countries agreed to a process whereby each will unilaterally design and communicate its contribution toward reducing greenhouse gas emissions in the atmosphere. This process is to be ratified in late 2015 in Paris. Will the Paris agreement mark a turning point in climate policy? Will it measure up to the ambitions proclaimed by the international community at the Durban meeting?

The PermaFRANCE network

Science.gov (United States)

Schoeneich, Philippe

2010-05-01

A French long term monitoring network of permafrost and frost related processes, named PermaFRANCE, is being built since two years. It will represent the French contribution to the Alpine wide PermaNET network. The PermaFRANCE network will focus not only on permafrost, but on all frost related phenomena at different altitudinal levels, including both thermal monitoring and process observation and monitoring : 1) continuous and discontinuous permafrost in rock walls : - thermal monitoring is mainly performed at the Aiguille du Midi (Mont Blanc massif) and includes rock surface temperature (RST) and temperature profils in medium depth boreholes (10 m) ; - inventory and observation of rockfall activity in high mountain rock walls : this action concerns the whole Mont Blanc area and is based on a hitorical inventory and an observation of current activity based on a network of observers and contributors ; 2) discontinuous permafrost is surficial deposits and flat bedrock : - thermal monitoring is performed on five rockglacier sites and includes ground surface temperature (GST) and annual BTS campaigns on some sites. Two medium depth boreholes (15 m) have been made in 2009 on one site, and equipped for thermal profile monitoring. A deep borehole (100 m) will be made in 2010 at 45° N latitude ; - geophysical monitoring is performed on 4 sites : repeated vertical electrical soundings exist for some sites since 20 years, and have been complemented since 2007 by eletrical resistivity tomography (ERT) and refraction seismics ; - surficial displacements of rockglaciers : surficial displacements are measured either by classical geodesy or by DGPS on 6 rockglaciers ; 3) sporadic permafrost at middle altitudes : - an inventory of cold scree slopes and biological investigations on soil and tree growth (dendrogeomorphology) have already been achieved ; - a thermal monitoring should be initiated on selected sites in 2010 ; 4) seasonal frost and frost/thaw cycles at middle and low

Regard sur la participation de populations marginalisées à la recherche-action. Le cas des squatteurs en Ile-de-France The participation of Marginalised populations in research-action: a case study of squatters in the Ile-de-France region (Paris and surrounding region

Directory of Open Access Journals (Sweden)

Lionel Pourtau

2011-05-01

Full Text Available La recherche-action comporte deux caractéristiques principales : elle met en œuvre la collaboration entre plusieurs types d’acteurs et vise une transformation de la réalité sociale. Elle possède des forces et des faiblesses différentes de la recherche à objectif strictement cognitif. L’article rend compte d’une recherche-action menée par des sociologues, des intervenants sociaux et des populations vivant en squats en Ile-de-France. Les auteurs analysent les enjeux méthodologiques qui se sont posés sur ce terrain particulier relevant de la sociologie de la déviance. Ceux-ci sont liés, notamment, à la participation de chaque groupe d’acteurs aux différentes étapes de la recherche, à la présence d’intérêts différents portés par chacun d’entre eux, et à la conciliation entre les principes habituellement de rigueur dans l’enquête sociologique et les principes de la recherche-action.Research-Action has two main objectives: to allow different players to cooperate, and to transform social reality. This methodology has both the strengths and the weaknesses of strictly cognitive research. In this article, the authors discuss a research-action project which brought together sociologists, social workers and squatters from the Ile-de-France region (Paris and surrounding region. Methodological issues that arise specifically in the context of deviance are addressed, notably the participation of the different players at different stages of the research project, their different areas of interest, as well as the reconciliation between more conventional sociological research and the principles of research-action.

Spotlight on crizotinib in the first-line treatment of ALK-positive advanced non-small-cell lung cancer: patients selection and perspectives

Directory of Open Access Journals (Sweden)

Giroux Leprieur E

2016-06-01

Full Text Available Etienne Giroux Leprieur,1,2 Vincent Fallet,3,4 Jacques Cadranel,3,4 Marie Wislez3,4 1Respiratory Diseases and Thoracic Oncology Department, APHP-Ambroise Paré Hospital, Boulogne-Billancourt, France; 2EA4340 Laboratory, UVSQ, Paris-Saclay University, France; 3Respiratory Diseases Department, APHP – Tenon Hospital, Paris, France; 4Sorbonne University, GRC 04, UPMC Univ Paris 06, France Abstract: Around 4% of advanced non-small-cell lung cancers (NSCLCs have an ALK rearrangement at the time of diagnosis. This molecular feature is more frequent in young patients, with no/light smoking habit and with adenocarcinoma pathological subtype. Crizotinib is a tyrosine kinase inhibitor, targeting ALK, ROS1, RON, and MET. The preclinical efficacy results led to a fast-track clinical development. The US Food and Drug Administration (FDA approval was achieved after the Phase I clinical trial in 2011 in ALK-rearranged advanced NSCLC progressing after a first-line treatment. In 2013, the randomized Phase III trial PROFILE-1007 confirmed the efficacy of crizotinib in ALK-rearranged NSCLC, compared to cytotoxic chemotherapy, in second-line setting or more. In 2014, the PROFILE-1014 trial showed the superiority of crizotinib in the first-line setting compared to the pemetrexed platinum doublet chemotherapy. The response rate was 74%, and the progression-free survival was 10.9 months with crizotinib. Based on these results, crizotinib received approval from the FDA and European Medicines Agency for first-line treatment of ALK-rearranged NSCLC. The various molecular mechanisms at the time of the progression (ALK mutations or amplification, ALK-independent mechanisms encourage performing re-biopsy at the time of progression under crizotinib. The best treatment strategy at the progression (crizotinib continuation beyond progression, switch to second-generation tyrosine kinase inhibitors, or cytotoxic chemotherapy depends on the phenotype of the progression, the

Colloquium on High Resolution Molecular Spectroscopy (16th) Held in Universite de Bourgogne, Dijon, France on 6-10 September 1999

Science.gov (United States)

1999-09-28

Chimica Fisica e Photophysique Mol6culaire, Physikalische Chemnie, Inorganica, Universit6 de Paris-Sud, ETH Zentrum, Universitý, de Bologna, Orsay... de la Materia, Consejo Superior de Investigaciones Cientificas, Serrano 123, 28006 Madrid, Spain; C. CLAVEAU and A. VALENTIN, Laboratoire de Physique...Cedex, France; J. C. LOPEZ and S. BLANCO, Departamento de Quimica- Fisica , Facultad de Ciencias, Universitad de Valladolid, 47071 Valladolid, Spain; A

Binding Nations through Art Quilts and a Visit to the U.S. Embassy in Paris as a Cultural Envoy

Directory of Open Access Journals (Sweden)

Riché Richardson

2009-09-01

Full Text Available In the spring of 2008 when Géraldine Chouard, who was helping to coordinate the landmark exhibition in France entitled “Un Patchwork de Cultures,” mentioned the U.S. Embassy in Paris’s interest in inviting me to the city to share some of my quilts as a part of this exhibition and to be a “Cultural Envoy,” I was honored and excited by the possibility. The opportunity to return to Paris under the auspices of the U.S. Embassy, which officially materialized through a grant from the U.S. Departmen...

The monuments of the UNESCO List under threat in the 21rst century: the Project "MONUNESCO-PARIS" (2012-2013)

Science.gov (United States)

Menendez, B.; Brimblecombe, P.; Deque, M.; Grossi, C. M.; Ionescu, A.; Lefevre, R. A.

2012-04-01

The banks of the River Seine in Paris are inscribed on the UNESCO List of the World Cultural Heritage since 1991 because they are studded with a succession of masterpieces such as Notre- Dame Cathedral, Sainte Chapelle, Louvre, Place de la Concorde, Tour Eiffel, and with prestigious museums: Louvre, Orsay, Quai Branly, Petit Palais…Unfortunately, these banks are crossed by the Pompidou urban motorway, an important and continuous source of atmospheric pollution. The aim of the Project is to evaluate the evolution of the weathering of limestone, glass and stained glass in the centre of Paris in the 21rst century by crossing Climate and Pollution Models with Dose-Response Functions (DRF) for limestone, glass and stained glass and with Climatology of Salt Transitions for limestone. A Lutetian limestone (« Courville Stone ») has been used for the construction and the restoration of the most important monuments (Notre-Dame, Louvre…) and haussmannian buildings in Paris. It has a fine grain, a medium porosity (19%) and contains 90% of CaO. The modern glass of windows and large contemporaneous façades has a Si-Ca-Na composition, it is chemically inert, has a low thermal inertia, a flat surface, no open porosity and no surface roughness, therefore it is very durable. The glass of stained glass windows has a Si-Ca-K composition and it is low durable. Using different climate and pollution scenarios of the 21rst century, the project will evaluate different schemes of material degradations: (i) - Recession of limestone surface; (ii) - Soiling of limestone surface; (iii) - Soiling of modern glass; (iv) - Leaching of ancient stained glass windows; (v) - Deterioration of limestone by salts. The British Hadley Models, the French Météo- France Arpège-Aladin Models and the ENSEMBLES Approach will be crossed with DRF and Climatology of Salts Transitions. An in-the-field inventory (stock at risk) of the surface occupied on the façades by each kind of material (stone

Electrical Energy Statistics for France 2002

International Nuclear Information System (INIS)

2003-11-01

Detailed statistics on electricity flows in France and on facilities. Regional data / Consumption per sector of activity / Records over last 10 years (definitive results). In 2002, national electrical consumption reached 449.9 TWh, an increase of 0.3% compared with 2001 (448.6 TWh). Adjusted for winter and summer climate contingencies, its growth rate was 0.9% compared with 2001. Consumption by customers connected at high or medium voltage levels came to 254.2 TWh, an increase of 0.8% compared with 2001 (252.3 TWh); consumption by customers connected at low voltage levels came to 165 TWh, a decrease of 0.8% compared with 2001 (166.4 TWh). Generation in France reached 534.3 TWh, an increase of 11.5 TWh or 2.2% compared with 2001 (522.8 TWh). This increase broke down between nuclear generation and conventional thermal generation. Net nuclear generation injected, as measured by RTE, came to 415.5 TWh in 2002, an increase of 4.0% compared with 2001 (399.6 TWh). Conventional thermal generation came to 51.1 TWh, an increase of 15.4 % compared with 2001 (44.3 TWh). Hydro-electric generation amounted to 65.5 TWh, a fall of 15.3% compared with 2001 (77.3 TWh). In terms of physical exchanges with foreign countries, France exported a net total of 77 TWh, an increase of 12.6% compared with 2001 (68.4 TWh). Contractual exchanges with foreign countries, recorded by RTE, fell by 9.9 % to reach a cumulative value for exports and imports of 107.8 TWh (compared with 120 TWh in 2001)

3He(d,p)4He reaction calculation with three-body Faddeev equations

International Nuclear Information System (INIS)

Oryu, S.; Uzu, E.; Sunahara, H.; Yamada, T.; Tabaru, G.; Hino, T.

1998-01-01

In order to investigate the 3 He-n-p system as a three-body problem, we have formulated 3 He-n and 3 H-p effective potentials using both a microscopic treatment and a phenomenological approach. In the microscopic treatment, potentials are generated by means of the resonating group method (RGM) based on the Minnesota nucleon-nucleon potential. These potentials are converted into separable form by means of the microscopic Pauli correct (MPC) method. The MPC potentials are properly formulated to avoid Pauli forbidden states. The phenomenological potentials are obtained by modifying parameters of the EST approximation to the Paris nucleon-nucleon potential, such that they fit the low-energy 3 He-n, 3 H-p, and 3 He-p phase shifts. Therefore, they describe the 3 He-n differential cross section, the polarization observables, and the energy levels of 4 He. The 3 He-n-p Faddeev equations are solved numerically. We reproduce correctly the ground state and the first excited state of 5 Li. Furthermore, the Paris-type potential is used to investigate the 3 He(d,p) 4 He reaction at a deuteron bombarding energy of 270 MeV, where the system is treated as a three-body problem. Results for the polarized and unpolarized differential cross sections demonstrate convergence of the Born series. (orig.)

Discrimination of Wild Paris Based on Near Infrared Spectroscopy and High Performance Liquid Chromatography Combined with Multivariate Analysis

Science.gov (United States)

Zhao, Yanli; Zhang, Ji; Yuan, Tianjun; Shen, Tao; Li, Wei; Yang, Shihua; Hou, Ying; Wang, Yuanzhong; Jin, Hang

2014-01-01

Different geographical origins and species of Paris obtained from southwestern China were discriminated by near infrared (NIR) spectroscopy and high performance liquid chromatography (HPLC) combined with multivariate analysis. The NIR parameter settings were scanning (64 times), resolution (4 cm−1), scanning range (10000 cm−1∼4000 cm−1) and parallel collection (3 times). NIR spectrum was optimized by TQ 8.6 software, and the ranges 7455∼6852 cm−1 and 5973∼4007 cm−1 were selected according to the spectrum standard deviation. The contents of polyphyllin I, polyphyllin II, polyphyllin VI, and polyphyllin VII and total steroid saponins were detected by HPLC. The contents of chemical components data matrix and spectrum data matrix were integrated and analyzed by partial least squares discriminant analysis (PLS-DA). From the PLS-DA model of NIR spectrum, Paris samples were separated into three groups according to the different geographical origins. The R2X and Q2Y described accumulative contribution rates were 99.50% and 94.03% of the total variance, respectively. The PLS-DA model according to 12 species of Paris described 99.62% of the variation in X and predicted 95.23% in Y. The results of the contents of chemical components described differences among collections quantitatively. A multivariate statistical model of PLS-DA showed geographical origins of Paris had a much greater influence on Paris compared with species. NIR and HPLC combined with multivariate analysis could discriminate different geographical origins and different species. The quality of Paris showed regional dependence. PMID:24558477

The amino acid and hydrocarbon contents of the Paris meteorite: Insights into the most primitive CM chondrite

Science.gov (United States)

Martins, Zita; Modica, Paola; Zanda, Brigitte; D'Hendecourt, Louis Le Sergeant

2015-05-01

The Paris meteorite is one of the most primitive carbonaceous chondrites. It is reported to be the least aqueously altered CM chondrite, and to have experienced only weak thermal metamorphism. We have analyzed for the first time the amino acid and hydrocarbon contents of this pristine meteorite by gas chromatography-mass spectrometry (GC-MS). When plotting the relative amino acids abundances of several CM chondrites according to the increasing hydrothermal scale (petrologic subtypes), from the CM2.7/2.8 Paris to the CM2.0 MET 01070, Paris has the lowest relative abundance of β-alanine/glycine (0.15), which fits with the relative abundances of β-alanine/glycine increasing with increasing aqueous alteration for CM chondrites. These results confirm the influence of aqueous alteration on the amino acid abundances and distribution. The amino acid analysis shows that the isovaline detected in this meteorite is racemic (D/L = 0.99 ± 0.08; L-enantiomer excess = 0.35 ± 0.5%; corrected D/L = 1.03; corrected L-enantiomer excess = -1.4 ± 2.6%). The identified hydrocarbons show that Paris has n-alkanes ranging from C16 to C25 and 3- to 5-ring nonalkylated polycyclic aromatic hydrocarbons (PAHs). The lack of alkylated PAHs in Paris seems to be also related to this low degree of aqueous alteration on its parent body. The extraterrestrial hydrocarbon content, suggested by the absence of any biomarker, may well have a presolar origin. The chemistry of the Paris meteorite may thus be closely related to the early stages of the solar nebula with a contribution from interstellar (molecular cloud) precursors.

France: National INIS Centre: New Directions and Main Achievements in an Evolving Context

International Nuclear Information System (INIS)

Surmont, Jérôme; Mouffron, Odile

2015-01-01

In a letter dated October 8, 1969 and addressed to the Director General of the IAEA, the French Governor of the IAEA Board of Governors gave his official consent for France to participate in the newborn INIS. At the same time, it was decided to establish the France National INIS Centre at the premises of the Central Documentation Department, located at the Saclay Nuclear Research Centre (French Atomic Energy Commission - CEA), near Paris. Forty-five years later, the Central Documentation has become the “Information Valorization Service” (SVI in French) which incorporates INIS, the CEA-Saclay Scientific Library and several other scientific and technical information-related activities (archives, scientific watch, collaborative work, bibliometric surveys, etc.). This brief look back over the last 20 years of the France National INIS Centre allows us to measure how far we have come and what choices we have had to make in a constantly evolving context. We have particularly stressed what, in our view, represents the most important mission of INIS, which is the preservation and dissemination of nuclear knowledge, in particular through the coverage and full text archiving of conferences and grey literature documents, with special attention paid to PhD Theses

Gaz de France 2006 annual report

International Nuclear Information System (INIS)

2006-01-01

Gaz de France is major European energy utility, which produces, purchases, transports, distributes and sells natural gas, electricity and related services for its residential, corporate and local government customers. Its strategic focuses are to develop an ambitious marketing strategy, pursue a supply and procurement policy that guarantees the Group's competitiveness, confirm its position as a benchmark infrastructure manager, and speed up its profitable growth in Europe. Gaz de France aligns its strategy with a concrete and ambitious sustainable development policy. Its growth model is based on responsiveness to customers and constructive dialogue with its employees and partners. This document is the activity report of the group for the year 2006. It presents: 1 - the corporate profile of the group; 2 - its strategies (energy, energy supply, infrastructures); 3 - its financial highlights; 4 - its governance, shareholders and human resources; 5 - the activities of the group (exploration and production, energy procurement, energy sales, services, transmission France, storage France, LNG terminals, distribution France, transmission and distribution international, research and development); 6 - its 2006 financial data and financial summary

Undocumented Youth Living Between the Lines: Urban Governance, Social Policy, and the Boundaries of Legality in New York City and Paris

Science.gov (United States)

Ruszczyk, Stephen P.

This dissertation compares the transition to adulthood of undocumented youth in New York and Paris, along with analysis of the construction of illegality in each city. In both the United States and France, national restrictions against undocumented immigrants increasingly take the form of deportations and limiting access to social rights. New York City and Paris, however, mitigate the national restrictions in important but different ways. They construct "illegality" differently, leading to different young adult outcomes and lived experiences of "illegality." This project uses seven years of multi-site ethnographic data to trace the effects of these mitigated "illegalities" on two dozen (male) youth. We can begin to understand the variation in these undocumented young men's social lives within and between cities by centering on (1) governance structure, the labyrinth of obtaining rights associated with citizenship, (2) citizenship, the possibility of gaining a legal status, steered in particular by civil society actors, and (3) identity, here centered on youths' negotiation of social mobility with the fear of enforcement. Biographical narratives show the shifts in social memberships as youth transition to new countries, new restrictions at adulthood, and new, limiting work. In New York, most social prospects are flattened as future possibilities are whittled down to ones focusing on family and wages. Undocumented status propels New York informants into an accelerated transition to adulthood, as they take on adult responsibilities of work, paying bills, and developing families. In Paris, youth experience more divergent processes of transitioning to adulthood. Those who are more socially integrated use a civil society actor to garner a (temporary) legal status, which does not lead to work opportunities. Those who are less socially integrated face isolation as they wait to gain status and access to better jobs. Paris undocumented youth are thus characterized by a

The Paris Climate Conference: What kind of international agreement in 2015?

International Nuclear Information System (INIS)

Lemmet, Sylvie; Watkinson, Paul; Navizet, Damien

2015-01-01

At stake during the 21. Climate Conference (COP21) to be held in Paris in 2015 is the adoption of a worldwide agreement that can be applied to all countries. This agreement, which will take effect by 2020, will focus not only on reducing greenhouse gases and adapting to climate change but also on funding and concrete actions for sustainable, resilient economic development. Throughout the coming year, France, which hosts and chairs the COP21, must see to it that a transparent, inclusive process allows all parties to express their viewpoints and be heard. An agreement is not the only result expected of this conference. For the sake of fairness and in order to limit global warming to 2 deg. C, pledges and commitments, including financial ones, from countries in favor of protecting the climate are expected too. International recognition will also have to be provided to climate-related initiatives that have already been launched

An Account of the Inaugural Tessier Skull Exhibition at the University of Paris Descartes.

Science.gov (United States)

Dusseldorp, Joseph Richard; Firmin, Françoise

2015-10-01

Paul Tessier is widely regarded as the father of modern craniofacial surgery. Upon his passing in 2008, his private collection of human skulls was purchased by the French Association of Facial Surgeons to ensure the collection would remain in France. The first public exhibition of the skulls was held in the medical museum of the University of Paris Descartes in April 2014. From this collection of skulls and the imagination of Tessier an entirely new specialty was created. Modern craniofacial surgery, now is an integral part of any pediatric plastic surgery department. Cranial and facial osteotomies have also become commonplace in both traumatic and aesthetic surgery. The goals for craniofacial deformity are now a return to completely normal appearance and function, as Tessier always believed they should be.

Sources and behavior of perchlorate ions (ClO4-) in chalk aquifer of Champagne-Ardenne, France: preliminary results

Science.gov (United States)

Cao, Feifei; Jaunat, Jessy; Ollivier, Patrick; Cancès, Benjamin; Morvan, Xavier; Hubé, Daniel; Devos, Alain; Devau, Nicolas; Barbin, Vincent; Pannet, Pierre

2018-06-01

Perchlorate (ClO4-) is an environmental contaminant of growing concern due to its potential human health effects and widespread occurrence in surface water and groundwater. Analyses carried out in France have highlighted the presence of ClO4- in drinking water of Champagne-Ardenne (NW of France), with two potential sources suspected: a military source related to the First World War and an agricultural source related to the past use of Chilean nitrates. To determine the sources of ClO4- in groundwater, major and trace elements, 2H and 18O, ClO3- and ClO4- ions and a list of 39 explosives were analyzed from 35 surface water and groundwater sampling points in the east of the city of Reims. ClO4- ions were found in almost all sampling points (32 out of 35) with a max value of 33 µg L-1. ClO4- concentrations were highest in groundwater ranging from 0.7 to 33 µg L-1 (average value of about 6.2 µg L-1) against from 4 µg L-1) were collected near a military camp, where huge quantities of ammunitions have been used, stored and destroyed during and after the First World War.

4th IEA International CCS Regulatory Network Meeting

Energy Technology Data Exchange (ETDEWEB)

NONE

2012-07-01

On 9 and 10 May 2012, the IEA International CCS Regulatory Network (Network), launched in Paris in May 2008 to provide a neutral forum for CCS regulators, policy makers and stakeholders to share updates and views on CCS regulatory developments, held its fourth meeting at the International Energy Agency (IEA) offices in Paris, France. The aim of the meeting was to: provide an update on government efforts to develop and implement carbon capture and storage (CCS) legal and regulatory frameworks; and consider ways in which governments are dealing with some of the more difficult or complex aspects of CCS regulation. This report summarises the proceedings of the meeting.

[Stays in Paris of professors and students from the Faculty of Pharmacy of Santiago de Compostela (Spain), 1900-1936].

Science.gov (United States)

Beatriz Arias, Brasa; Landín Pérez, Mariana

2011-10-01

In the early twentieth century, if there were an European Capital of biomedical research, it was definitely Paris. It was in this city where microbiology was born in the 19th century due to the crucial influence of Louis Pasteur. In 1888 he founded the Pasteur Institute in Paris where the rabies vaccine, that Pasteur himself had discovered in 1885, was administrated. This institution was also a place to continue his research on infectious diseases and to disseminate its findings. It is a private non-profit state-approved foundation that has attracted along the years many scientists from France and abroad who have been traditionally called "pasteuriens". So it was a world reference centre which has produced important scientific discoveries at a rapid pace and where resources both material and human, were abundant. The Pasteur institute therefore became one of the favourite research facilities of teachers and students from Spanish universities during the first third of the twentieth century, thanks to new regulations that encouraged training abroad. Scholarship policy promoted by the Spanish Government by an organization called Junta para la Ampliación de Estudios e Investigaciones Científicas (Council for Higher Studies and Scientific Research from, 1907 to 1936) formed scientists abroad. The Faculty of Pharmacy of Santiago de Compostela sent some of its members to the French capital between 1905 and 1933. We found that the vast majority chose the Pasteur Institute to conduct the studies of biological chemistry and drug synthesis, but always dependent of the Faculty of Pharmacy of Paris. Our study focuses on teachers and students who went to Paris, the dates, the course of their scientific stay and how these studies influenced their later work, once they returned to the Faculty of Pharmacy of Santiago de Compostela.

Paris Commune Imagery in China's Mass Media.

Science.gov (United States)

Meiss, Guy T.

The role of ideology in mass media practices is explored in an analysis of the relation between the Paris Commune of 1871 and the Shanghai Commune of 1967, two attempts to translate the philosophical concept of dictatorship of the proletariat into some political form. A review of the use of Paris Commune imagery by the Chinese to mobilize the…

Morphological diversity of wild medicinal Paris L. from China and ...

African Journals Online (AJOL)

Paris L. (Trilliaceae) is a temperate genus of about 24 perennial herbaceous species distributed from Europe to Eastern Asia. Paris is notable in China for its medicinal value. An investigation was conducted to determine the variations of 27 morphological characters of 196 accessions from 8 populations of medicinal Paris ...

Panorama of mining activities in France during 1995

International Nuclear Information System (INIS)

Michel, J.C.; Bornuat, M.; Mouron, R.

1996-01-01

The French mining industry in 1995 continued to follow the overall trend of the past 5 to 10 years characterized mainly by: 1)a decline in the production of most energy materials: oil, coal, uranium. This decline will probably be further accentuated over the next two years with the planned closure of Lodeve (U), Forbach, La Mure and Carmaux (coal). Gas production, however, has remained relatively stable at 4.7 to 5 billion m''3 per year. 2)a scarcity of metal ore mines in Metropolitan France 3)an increase in the production of gold that, in 1995, came close to 6 tonnes in Metropolitan France and reached 8.4 tonnes with French Guiana. 4)the development of metal ore mining in the DOM-TOM 5) divergent developments in the industrial mineral sector: downward trends for sulfur, talc, andalusite, diatomite and silica; upward trends for kaolin, mica, feldspar and salt. Although overall the decline in mine production continued, the panorama does include some positive aspects: 1)France's independence in the energy sector exceeded the half-way mark two years ago and 1995 saw an appreciable decrease in the nation's energy bill compared to 1994. 2)French companies involved in metal mining have adapted themselves to world trends: Cogema has diversified its uranium sources mainly through its mining interests in Canada; Eramet has strengthened its activities by becoming the majority shareholder of Comilog, a manganese producer in Gabon. France also has mining interests in Africa, South America and Europe through LaSource Compagnie Miniere (BRGM and Normandy) created in 1995 3) France's position and production in the industrial mineral sector are significant at European scale, if not at world scale, as regards andalusite, diatomite, kaolin, mica, feldspar, sulfur, potassium, salt and industrial silica. Finally, mention must be made of the increasing environmental awareness by the French authorities and mining companies. This has resulted in a major rehabilitation of mine sites by

Enterovirus Migration Patterns between France and Tunisia.

Science.gov (United States)

Othman, Ines; Mirand, Audrey; Slama, Ichrak; Mastouri, Maha; Peigue-Lafeuille, Hélène; Aouni, Mahjoub; Bailly, Jean-Luc

2015-01-01

The enterovirus (EV) types echovirus (E-) 5, E-9, and E-18, and coxsackievirus (CV-) A9 are infrequently reported in human diseases and their epidemiologic features are poorly defined. Virus transmission patterns between countries have been estimated with phylogenetic data derived from the 1D/VP1 and 3CD gene sequences of a sample of 74 strains obtained in France (2000-2012) and Tunisia (2011-2013) and from the publicly available sequences. The EV types (E-5, E-9, and E-18) exhibited a lower worldwide genetic diversity (respective number of genogroups: 4, 5, and 3) in comparison to CV-A9 (n = 10). The phylogenetic trees estimated with both 1D/VP1 and 3CD sequence data showed variations in the number of co-circulating lineages over the last 20 years among the four EV types. Despite the low number of genogroups in E-18, the virus exhibited the highest number of recombinant 3CD lineages (n = 10) versus 4 (E-5) to 8 (E-9). The phylogenies provided evidence of multiple transportation events between France and Tunisia involving E-5, E-9, E-18, and CV-A9 strains. Virus spread events between France and 17 other countries in five continents had high probabilities of occurrence as those between Tunisia and two European countries other than France. All transportation events were supported by BF values > 10. Inferring the source of virus transmission from phylogenetic data may provide insights into the patterns of sporadic and epidemic diseases caused by EVs.

Access to employment among African migrant women living with HIV in France: opportunities and constraints.

Science.gov (United States)

Gerbier-Aublanc, Marjorie; Gosselin, Anne

2016-08-01

HIV in France particularly affects sub-Saharan migrants as they accounted for 31% of the new diagnoses in 2013. The objective of this study is to investigate the access to and the experience of employment among migrant women living with HIV in France. We use a mixed-method approach. The quantitative data come from the ANRS Parcours study, a life-event survey conducted in 2012-2013 in 70 health centres which collected year-by-year detailed information on living conditions about 755 sub-Saharan women migrants in the greater Paris region (470 with HIV and 285 without HIV). The qualitative data have been collected independently in the same region through socio-ethnographic observations and interviews conducted in 8 HIV-positive migrant organisations and among 35 women-members from 2011 to 2013. Two main results are noteworthy. First, being HIV-positive unexpectedly gives sub-Saharan migrant women a quicker access to employment thanks to the social support they find in migrant organisations: in the third year in France in median (versus 5th year among HIV-negative group). This effect of being HIV-positive on the access to employment remains all things being equal in a discrete-time logistic regression (aOR [95% CI] HIV+: 1.4[1.1;1.8]). Second, their employment situation remains strongly shaped by the racial division of work existing in France and they develop individual strategies to negotiate this constraint: for example, temporary jobs and working as health mediators. The type of jobs they find, mainly in the care sector, force them to carefully hide their HIV status because they fear discrimination at work. Not only migrant women endure structural discrimination in a segmented labour market, but they also anticipate HIV-related discrimination related to caring activities. Thus, the design and implementation of programmes that address stigma should consider structural discrimination to improve PLWHA's working experiences.

Remote sensing of GHG over Paris megacity and Orléans forest using ground-based QualAir FTS and TCCON-Orléans

Science.gov (United States)

Te, Y.; Jeseck, P.; Da Costa, J.; Deutscher, N. M.; Warneke, T.; Notholt, J.

2012-04-01

In a growing world with more than 7 billion inhabitants and big emerging countries such as China, Brazil and India, emissions of anthropogenic pollutants are increasing continuously. Monitoring and control of atmospheric pollutants in megacities have become a major challenge for scientists and public health authorities in environmental research area. The QualAir platform at University Pierre et Marie Curie (UPMC), is an innovating experimental research platform dedicated to survey greenhouse gases (GHGs) and urban air quality. As one of the major instruments of the QualAir platform, the ground-based Fourier transform spectrometer (QualAir FTS, IFS 125HR model) analyses the composition of the urban atmosphere of Paris, which is the third European megacity. The continuous monitoring of atmospheric pollutants is essential to improve the understanding of urban air pollution processes. Associated with a sun-tracker, the QualAir remote sensing FTS operates in solar infrared absorption and enables to monitor many trace gases, and to follow up their variability in the Ile-de-France region. A description of the QualAir FTS will be given. Concentrations of atmospheric GHG, especially CO2 and CH4, are retrieved by the radiative transfer model PROFFIT. Located in the centre of Paris, the QualAir FTS can provide new and complementary urban measurements as compared to unpolluted ground-based stations of existing networks (NDACC and TCCON). The work made by LPMAA to join the TCCON network will also be presented. TCCON-Orléans is a ground-based FTS of the TCCON network located in the forest of Orléans (100 km south of Paris). Preliminary comparisons of GHGs measurements from both sites will be shown. Such ground-based information will help to better characterize regional GHGs, especially regarding anthropogenic emissions and trends.

Air oxidation of samples from different clay formations of East Paris basin: quantitative and qualitative consequences on the dissolved organic matter

International Nuclear Information System (INIS)

Blanchart, Pascale; Faure, Pierre; Michels, Raymond; Parant, Stephane

2012-01-01

Document available in extended abstract form only. During the excavation and the building of an underground research laboratory in clay geological formations, exposure to air is one of the most important parameters affecting the composition of fossil organic matter. Indeed the net effect of air oxidation of the organic matter is enrichment in oxygen and carbon combined with a loss of hydrogen. Effluents formed are CO 2 and water as well as the liberation of hydrocarbons. This process may have an impact on water chemistry of the clay, especially on the quantity and composition of Dissolved Organic Matter (DOM). The clays studied were the following and may be distinguished on the basis of their organic matter content: - The Callovo-Oxfordian argillite, collected in the Bure Underground Research Laboratory (Meuse, France), which contains a mixture of type II and III kerogen; - The Toarcian shales of East Paris Basin collected from drilling EST 204 (Meuse, France) contains type II kerogen; - The Kimmeridgian shales of East Paris Basin collected from drilling HTM 102 (Meuse, France) also contains type II kerogen. The powdered clay samples were oxidized in a ventilated oven at 100 C under air flow during 2, 256, 512 and 1088 hours for Callovo-Oxfordian samples and during 512 and 2048 hours for Toarcian and Kimmeridgian samples. The DOM of each sample was extracted by soxhlet using pure water. Different analyses were carried out: - Quantitative evolution of DOM with the oxidation process; - Evolution of several chemical parameters of DOM with oxidation using molecular analyses (PyGC-MS) molecular weight distribution (GPC-HPLC) as well as spectroscopic measurements (3D-Fluorescence). Increasing oxidation induces an increase of DOC values for all samples. Also, Changes in the chemical composition of the DOM are observed: decrease in the molecular weight range; enrichment in acidic functional groups (alkane-dioic acids, alkanoic acids, aromatics poly acids). Moreover the

The myriad challenges of the Paris Agreement

Science.gov (United States)

Mitchell, Dann; Allen, Myles R.; Hall, Jim W.; Muller, Benito; Rajamani, Lavanya; Le Quéré, Corinne

2018-05-01

The much awaited and intensely negotiated Paris Agreement was adopted on 12 December 2015 by the Parties to the United Nations Framework Convention on Climate Change. The agreement set out a more ambitious long-term temperature goal than many had anticipated, implying more stringent emissions reductions that have been under-explored by the research community. By its very nature a multidisciplinary challenge, filling the knowledge gap requires not only climate scientists, but the whole Earth system science community, as well as economists, engineers, lawyers, philosophers, politicians, emergency planners and others to step up. To kick start cross-disciplinary discussions, the University of Oxford's Environmental Change Institute focused its 25th anniversary conference upon meeting the challenges of the Paris Agreement for science and society. This theme issue consists of review papers, opinion pieces and original research from some of the presentations within that meeting, covering a wide range of issues underpinning the Paris Agreement. This article is part of the theme issue `The Paris Agreement: understanding the physical and social challenges for a warming world of 1.5°C above pre-industrial levels'.

The brain signature of paracetamol in healthy volunteers: a double-blind randomized trial

Directory of Open Access Journals (Sweden)

Pickering G

2015-07-01

Full Text Available Gisèle Pickering,1–3 Adrian Kastler,4 Nicolas Macian,1,2 Bruno Pereira,5 Romain Valabrègue,6 Stéphane Lehericy,6 Louis Boyer,4,7 Claude Dubray,1–3 Betty Jean4 1CHU Clermont-Ferrand, Centre de Pharmacologie Clinique, 2Centre d’Investigation Clinique – Inserm 1405, 3Clermont Université, Laboratoire de Pharmacologie, Faculté de médecine, 4CHU Gabriel Montpied, Clermont-Ferrand, Service d’Imagerie Ostéo-articulaire thoracique et neurologique, 5CHU Clermont-Ferrand, Délégation Recherche Clinique et à l’Innovation, Clermont-Ferrand, France; 6Institut du Cerveau et de la Moelle epiniere – ICM, Centre de NeuroImagerie de Recherche CENIR, Inserm U1127, CNRS UMR 7225, Sorbonne Universités, UPMC University Paris, Paris, France, Department of Neuroradiology, Groupe Hospitalier Pitié-Salpêtrière, Paris, France; 7UMR CNRS UdA 6284, Clemont-Ferrand, France Background: Paracetamol’s (APAP mechanism of action suggests the implication of supraspinal structures but no neuroimaging study has been performed in humans.Methods and results: This randomized, double-blind, crossover, placebo-controlled trial in 17 healthy volunteers (NCT01562704 aimed to evaluate how APAP modulates pain-evoked functional magnetic resonance imaging signals. We used behavioral measures and functional magnetic resonance imaging to investigate the response to experimental thermal stimuli with APAP or placebo administration. Region-of-interest analysis revealed that activity in response to noxious stimulation diminished with APAP compared to placebo in prefrontal cortices, insula, thalami, anterior cingulate cortex, and periaqueductal gray matter.Conclusion: These findings suggest an inhibitory effect of APAP on spinothalamic tracts leading to a decreased activation of higher structures, and a top-down influence on descending inhibition. Further binding and connectivity studies are needed to evaluate how APAP modulates pain, especially in the context of repeated

The chemical industry of uranium in France

International Nuclear Information System (INIS)

Goldschmidt, B.

1955-01-01

The actual CEA program is concerned with the construction of two large graphite reactors, each of those containing at least one hundred tons of uranium metal with nuclear purity. The uranium for these two reactors will be regularly supplied by new resources discovered in France and Madagascar in the last five years. The working and treatment of such ore have led to the creation of an important french industry of which the general outline and principle are described. The operated ores have got different natures and concentration, individual characteristics are described for the main ores.The most high-grade ore are transported to a central plant in Bouchet near Paris; the low-grade ore are concentrated by physical methods or chemical processes of which principles and economy are studied with constancy. The acid processes are the only used until now, although the carbonated alkaline processes has been studied in France. The next following steps after the acid process until the obtention of uranium rich concentrate are described. The purification steps of uranium compounds to nuclear purity material are described as well as the steps to elaborate metal of which the purity grade will be specify. Finally, the economic aspects of uranium production difficulty will be considered in relation with technical progresses which we can expect to achieve in the future. (M.P.)

Investigation of airways using MDCT for visual and quantitative assessment in COPD patients

Directory of Open Access Journals (Sweden)

Pierre-Yves Brillet

2008-03-01

Full Text Available Pierre-Yves Brillet1, Catalin I Fetita2, Amaury Saragaglia2, Anne-Laure Brun3, Catherine Beigelman-Aubry3, Françoise Prêteux2, Philippe A Grenier31Department of Radiology, Avicenne Hospital, Assistance Publique–Hôpitaux de Paris, Université Léonard de Vinci–Paris Nord, EA 2361, Bobigny, France; 2ARTEMIS Department, Institut National des Télécommunications, Université Paris V, Evry, France; 3Department of Radiology, Pitié-Salpêtrière Hospital, Assistance Publique–Hôpitaux de Paris, Université Pierre et Marie Curie, Paris, FranceAbstract: Multidetector computed tomography (MDCT acquisition during a single breath hold using thin collimation provides high resolution volumetric data set permitting multiplanar and three dimensional reconstruction of the proximal airways. In chronic obstructive pulmonary disease (COPD patients, this technique provides an accurate assessment of bronchial wall thickening, tracheobronchial deformation, outpouchings reflecting dilatation of the submucous glands, tracheobronchomalacia, and expiratory air trapping. New software developed to segment adequately the lumen and walls of the airways on MDCT scans allows quantitative assessment of the airway dimensions which has shown to be reliable in clinical practice. This technique can become important in longitudinal studies of the pathogenesis of COPD, and in the assessment of therapeutic interventions.Keywords: COPD – tracheobronchial tree, multidetector CT – airway remodeling, tracheobronchomalacia

Paris Convention on third party liability in the field of nuclear energy and Brussels Convention Supplementary to the Paris Convention

International Nuclear Information System (INIS)

1989-01-01

This new bilingual (English and French) edition of the 1960 Paris Convention and 1963 Brussels Supplementary Convention incorporates the provisions of the Protocols which amended each of them on two occasions, in 1964 and 1982. The Expose des motifs to the Paris Convention, as revised in 1982 is also included in this pubication. (NEA) [fr

Where are the radioactive wastes in France? Brochure no 3; Ou sont les dechets radioactifs en France? Brochure no 3

Energy Technology Data Exchange (ETDEWEB)

NONE

2004-07-01

This document is one of the 6 regional brochures which make the geographical inventory of radioactive wastes in France. For each region, a table lists the recorded sites and a regional map localizes those having a detailed descriptive file. These files mention the most important waste owners (medical, research, nuclear and military industries), the type of waste and the type of management. The polluted sites are also mentioned, even if they are already decontaminated. The volume no 3 concerns the Nord-Pas-de-Calais, Picardie, Champagne-Ardenne, Bourgogne, Alsace, Lorraine, Franche-Comte regions. (J.S.)

U.S. Navy Employment Options for Unmanned Surface Vehicles (USVs)

Science.gov (United States)

2013-01-01

the Navy had cleared in compliance with the Paris Peace Accords. The second condition under which minefield proofing is conducted is when there is...www.gdrs.com/about/profile/pdfs/UDTPacific2006_4A3_.pdf Bertram, Volker, “Unmanned Surface Vehicles: A Survey,” Brest , France: ENSIETA, 2008. As of

Urban compaction vs city sprawl: impact of road traffic on air quality in the greater Paris

Science.gov (United States)

Etuman Arthur, Elessa; Isabelle, Coll; Vincent, Viguie; Nicolas, Coulombel; Julie, Prud'homme

2017-04-01

Urban pollution remains a major sanitary and economic concern. In France, particulate pollution is known to cause 48,000 premature deaths every year (Santé Publique France, 2016), while the economic cost of air pollution reaches almost 25 billion euros per year (CGDD, 2012). In the Greater Paris, despite strengthened emission standards, restricted traffic areas, car-sharing and incentives for electric vehicle use, road transport plays a substantial role in the exposure of inhabitants to high levels of pollutants. In this context, urban planning could possibly constitute an innovative strategy to reduce emissions from road traffic, through its actions on transport demand, travel distances, modal shift (public transportation, cycling, walking...) or even proximity to emitters. We have developed a multi-scalar modeling of urban pollution by coupling an urban economic growth model NEDUM (CIRED), a model for urban mobility (LISA), a traffic emission model (LISA) and the CHIMERE Chemistry-Transport model (CTM) for air quality simulation (LISA). The innovative aspect of this modeling system is to integrate into a classic CTM the mechanisms underlying the dynamics of an urban system. This way, we establish a quantitative and comprehensive link between a given urban scenario, the associated public and individual transport matrix, and local air quality. We then make it possible to highlight the levers of energy consumption reductions inside compact or sprawled cities. We have been working on the Ile de France region (centered on the Paris agglomeration) which relies on a broad urban structure of megacity, a high density of housing and an expanding urban peripheral zone, clearly raising the issue of transport demand, mobility and traffic congestion. Two scenarios, considering opposite urban development policies from the 1960s to 2010, have been simulated over the whole modelling chain. The first one promotes a dense and compact city while the second favors city spread

Rationale, Design, and Baseline Data of the Insulin Glargine (Lantus) Versus Insulin Detemir (Levemir) Treat-To-Target (L2T3) Study: A Multinational, Randomized Noninferiority Trial of Basal Insulin Initiation in Type 2 Diabetes

NARCIS (Netherlands)

Swinnen, Sanne G. H. A.; Snoek, Frank J.; Dain, Marie-Paule; DeVries, J. Hans; Hoekstra, Joost B. L.; Holleman, Frits

2009-01-01

Objective: To discuss the design and baseline data of the Lantus (R) (sanofi-aventis, Paris, France) versus Levemir (R) (Novo Nordisk A/S, Bagsvaerd, Denmark) Treat-To-Target (L2T3) study, a multinational, randomized comparison between the basal insulin analogs insulin glargine and insulin detemir.

Operations in California during the Mexican American War

Science.gov (United States)

2016-05-26

assertion that he was on private business. On December 10, 1845 he arrived at Vera Cruz and proceeded overland to Mexico City where the Paredes revolution...Majesty’s Ship “Collingwood” From 1844-1848 (Paris, France: E . Briére, rue Sainte-Anne, 1850), 162-163.The policy of non- interference toward...From 1844-1848. Paris, France: E . Briére, rue Sainte-Anne, 1850. Watson, Douglas S. “The First Mail Contract in California.” California Historical Quarterly 10, no. 4 (December 1931): 353-354.

Pharmacokinetics and safety of DTS-108, a human oligopeptide bound to SN-38 with an esterase-sensitive cross-linker in patients with advanced malignancies: a Phase I study

Directory of Open Access Journals (Sweden)

Coriat R

2016-11-01

Full Text Available Romain Coriat,1 Sandrine J Faivre,2 Olivier Mir,3 Chantal Dreyer,2 Stanislas Ropert,3 Mohammed Bouattour,2 Robert Desjardins,4 François Goldwasser,3 Eric Raymond5 1Gastroenterology and Digestive Oncology Unit, Cochin Teaching Hospital, Université Paris Descartes Sorbonne Paris Cité, Paris, 2Department of Medical Oncology, Beaujon Teaching Hospital, Université Paris Diderot, Paris 7, Clichy, 3Department of Medical Oncology, Cochin Teaching Hospital, Université Paris Descartes Sorbonne Paris Cité, Paris, France; 4Drais Pharmaceuticals, Bridgewater, NJ, USA; 5Groupe Hospitalier Paris Saint-Joseph, Paris, France Background: DTS-108 is a hydrosoluble prodrug, where the SN-38 moiety is covalently linked to a 20-amino acid vector peptide by a specific esterase-sensitive cross-linker, releasing 7-ethyl-10-hydroxycampthotecin (SN-38 by esterase bond cleavage. Methods: The pharmacokinetics of DTS-108, adverse events graded according to NCI-CTCv3.1, dose-limiting toxicities at cycle 1, the maximum tolerated dose (MTD, and the recommended Phase II dose (RP2D of intravenous DTS-108 (1–2 hours every 2 weeks were evaluated in a first-in-human Phase I study in patients with advanced/metastatic carcinomas, according to an accelerated dose escalation design. SN-38 and SN-38 glucuronide (SN-38G levels were evaluated with fluorescence high-performance liquid chromatography (HPLC test, then liquid chromatography–tandem mass spectrometry (LC/MS/MS methods. Results: Forty-two patients received DTS-108 across 14 dosing cohorts (range 3–416 mg/m2. At 416 mg/m2, three out of six patients had grade 4 neutropenia thereby defining the MTD and the RP2D at 313 mg/m2. Fluorescence HPLC was inaccurate to quantify DTS-108 and its metabolites (SN-38 and SN-38G. New processes and analytical LC/MS/MS methods for testing SN-38 were implemented. At a dose of 313 mg/m2, mean DTS-108, SN-38, and SN-38G area under the plasma concentration–time curve to infinity

An office building of Paris city air-conditioned by an aquifer-source heat pump; Un immeuble parisien climatise par une thermofrigopompe sur nappe phreatique

Energy Technology Data Exchange (ETDEWEB)

Anon.

2003-09-01

A 7000 m{sup 2} office building of Paris (France) is equipped with an aquifer-source heat pump for the space heating and cooling. This choice allows to save 28400 euros of heating/cooling expenses each year with respect to other solutions. The equipment ensures also the production of hot and chilled water and the calories recovered from the refrigeration system are used to supply the space heating needs of the building. This paper describes the equipments (heat pump, heat exchangers, ventilation-convection systems), the centralized control system and the cost-benefit aspects. (J.S.)

El Gran Proyecto Urbano ”Paris Rive Gauche”: La transformación de un baldío ferroviario-industrial en un nuevo barrio parisino / The Great Urban Project

Directory of Open Access Journals (Sweden)

Duval-Zack, Chloé

2006-11-01

Full Text Available “Paris Rive Gauche” es el proyecto urbano más importante que conoció la ciudad desde la remodelación de Haussmann. El perímetro de intervención, de aproximadamente unas 130 hectáreas de terrenos baldíos de origen ferroviario-industriales, se localiza intramuros a lo largo del Sena y del tejido urbano del distrito 13. Para concretar su política urbana y crear un nuevo barrio, el Municipio, junto con la SEMAPA, formalizó un programa ambicioso de revitalización, mediante la mezcla de funciones urbanas y la construcción de la Biblioteca Nacional de Francia como proyecto detonante./"Paris Rive Gauche" is the most important urban project in Paris since the Haussmann's remodelling. The area of intervention, approximately 130 hectares of railways and abandoned industries, is located intra-muros (within the walls along the Seine and the 13th district. To translate the urban politics and to create a new neighborhood, the City, together with the SEMAPA, formalized an ambitious program of revitalisation, with the mixture of urban functions and the construction of the National Library of France as a trigger project.

6th International Workshop on New Computational Methods for Inverse Problems

International Nuclear Information System (INIS)

2016-01-01

methods, learning methods, convex optimization, free discontinuity problems, metamodels, proper orthogonal decomposition, reduced models for the inversion, non-linear inverse scattering, image reconstruction and restoration, and applications (bio-medical imaging, nondestructive evaluation...). NCMIP 2016 was a one-day workshop held in May 2016 which attracted around seventy attendees. Each of the submitted papers has been reviewed by two reviewers. There have been eleven accepted papers. In addition, three international speakers were invited to present a longer talk. The workshop was supported by Institut Farman (ENS Cachan, CNRS) and endorsed by the following French research networks: GDR ISIS, GDR MIA, GDR MOA, GDR Ondes. The program committee acknowledges the following research laboratories: CMLA, LMT, LURPA and SATIE. Eric Vourc'h and Thomas Rodet Workshop co-chairs: Eric Vourc'h, SATIE laboratory, Ecole Normale Supérieure de Cachan, CNRS, France Thomas Rodet, SATIE laboratory, Ecole Normale Supérieure de Cachan, CNRS, France Technical program committee: Alexandre Baussard, ENSTA Bretagne, Lab-STICC, France Marc Bonnet, ENSTA, ParisTech, France Laure Blanc-Féraud, I3S laboratory and INRIA Nice Sophia-Antipolis, France Antonin Chambolle, CMAP, Ecole Polytechnique, CNRS, France Oliver Dorn, School of Mathematics, University of Manchester, UK Cécile Durieu, SATIE, ENS Cachan, CNRS, France Laurent Fribourg, LSV, ENS Cachan, CNRS, France Jerôme Idier, IRCCyN Laboratory, Ecole Centrale de Nantes, France Pierre-Yves Joubert, IEF, Paris-Sud University, CNRS, France Marc Lambert, Geeps Laboratory, CNRS, CentraleSupElec, Paris-Sud University, France Giacomo Oliveri, eledia research center/eledia@L2S group, University of Trento, Italy Dominique Lesselier, L2S Laboratory, CNRS, CentraleSupElec, Paris-Sud University, France Matteo Pastorino, DIBE, University of Genoa, Italy Gabriel Peyré, Ceremade laboratory, University of Paris Dauphine, France Anthony Quinn

Ice-free Arctic projections under the Paris Agreement

Science.gov (United States)

Sigmond, Michael; Fyfe, John C.; Swart, Neil C.

2018-05-01

Under the Paris Agreement, emissions scenarios are pursued that would stabilize the global mean temperature at 1.5-2.0 °C above pre-industrial levels, but current emission reduction policies are expected to limit warming by 2100 to approximately 3.0 °C. Whether such emissions scenarios would prevent a summer sea-ice-free Arctic is unknown. Here we employ stabilized warming simulations with an Earth System Model to obtain sea-ice projections under stabilized global warming, and correct biases in mean sea-ice coverage by constraining with observations. Although there is some sensitivity to details in the constraining method, the observationally constrained projections suggest that the benefits of going from 2.0 °C to 1.5 °C stabilized warming are substantial; an eightfold decrease in the frequency of ice-free conditions is expected, from once in every five to once in every forty years. Under 3.0 °C global mean warming, however, permanent summer ice-free conditions are likely, which emphasizes the need for nations to increase their commitments to the Paris Agreement.

PARIS reprograms glucose metabolism by HIF-1α induction in dopaminergic neurodegeneration.

Science.gov (United States)

Kang, Hojin; Jo, Areum; Kim, Hyein; Khang, Rin; Lee, Ji-Yeong; Kim, Hanna; Park, Chi-Hu; Choi, Jeong-Yun; Lee, Yunjong; Shin, Joo-Ho

2018-01-22

Our previous study found that PARIS (ZNF746) transcriptionally suppressed transketolase (TKT), a key enzyme in pentose phosphate pathway (PPP) in the substantia nigra (SN) of AAV-PARIS injected mice. In this study, we revealed that PARIS overexpression reprogrammed glucose metabolic pathway, leading to the increment of glycolytic proteins along with TKT reduction in the SN of AAV-PARIS injected mice. Knock-down of TKT in differentiated SH-SY5Y cells led to an increase of glycolytic enzymes and decrease of PPP-related enzymes whereas overexpression of TKT restored PARIS-mediated glucose metabolic shift, suggesting that glucose metabolic alteration by PARIS is TKT-dependent. Inhibition of PPP by either PARIS overexpression or TKT knock-down elevated the level of H 2 O 2 , and diminished NADPH and GSH levels, ultimately triggering the induction of HIF-1α, a master activator of glycolysis. In addition, TKT inhibition by stereotaxic injection of oxythiamine demonstrated slight decrement of dopaminergic neurons (DNs) in SN but not cortical neurons in the cortex, suggesting that TKT might be a survival factor of DNs. In differentiated SH-SY5Y, cell toxicity by GFP-PARIS was partially restored by introduction of Flag-TKT and siRNA-HIF-1α. We also observed the increase of HIF-1α and glycolytic hexokinase 2 in the SN of Parkinson's disease patients. Taken together, these results suggest that PARIS accumulation might distort the balance of glucose metabolism, providing clues for understanding mechanism underlying selective DNs death by PARIS. Copyright © 2017 Elsevier Inc. All rights reserved.

2. orientation council. National observatory on the climatic change effects in France and in overseas territories and Departments; 2. conseil d'orientation. Observatoire national sur les effets du rechauffement climatique en France metropolitaine et dans les departements et territoires d'outre-mer

Energy Technology Data Exchange (ETDEWEB)

NONE

2003-11-01

This document provides the transparencies presented at the 2. orientation council concerning the climatic change effects. The participation of the ONERC to the colloquium on ''managers facing the climatic risks'', 23-24 june 2003 in Paris and the preparation to the technical assistance market, are discussed. The document presents also the heat wave of summer 2003 in France and the first reflexions on the adaptation. Some action principles are proposed. (A.L.B.)

Simulating the formation of carbonaceous aerosol in a European Megacity (Paris during the MEGAPOLI summer and winter campaigns

Directory of Open Access Journals (Sweden)

C. Fountoukis

2016-03-01

Full Text Available We use a three-dimensional regional chemical transport model (PMCAMx with high grid resolution and high-resolution emissions (4 × 4 km2 over the Paris greater area to simulate the formation of carbonaceous aerosol during a summer (July 2009 and a winter (January/February 2010 period as part of the MEGAPOLI (megacities: emissions, urban, regional, and global atmospheric pollution and climate effects, and Integrated tools for assessment and mitigation campaigns. Model predictions of carbonaceous aerosol are compared against Aerodyne aerosol mass spectrometer and black carbon (BC high time resolution measurements from three ground sites. PMCAMx predicts BC concentrations reasonably well reproducing the majority (70 % of the hourly data within a factor of two during both periods. The agreement for the summertime secondary organic aerosol (OA concentrations is also encouraging (mean bias = 0.1 µg m−3 during a photochemically intense period. The model tends to underpredict the summertime primary OA concentrations in the Paris greater area (by approximately 0.8 µg m−3 mainly due to missing primary OA emissions from cooking activities. The total cooking emissions are estimated to be approximately 80 mg d−1 per capita and have a distinct diurnal profile in which 50 % of the daily cooking OA is emitted during lunch time (12:00–14:00 LT and 20 % during dinner time (20:00–22:00 LT. Results also show a large underestimation of secondary OA in the Paris greater area during wintertime (mean bias =  −2.3 µg m−3 pointing towards a secondary OA formation process during low photochemical activity periods that is not simulated in the model.

Simulating the formation of carbonaceous aerosol in a European Megacity (Paris) during the MEGAPOLI summer and winter campaigns

Science.gov (United States)

Fountoukis, Christos; Megaritis, Athanasios G.; Skyllakou, Ksakousti; Charalampidis, Panagiotis E.; Denier van der Gon, Hugo A. C.; Crippa, Monica; Prévôt, André S. H.; Fachinger, Friederike; Wiedensohler, Alfred; Pilinis, Christodoulos; Pandis, Spyros N.

2016-03-01

We use a three-dimensional regional chemical transport model (PMCAMx) with high grid resolution and high-resolution emissions (4 × 4 km2) over the Paris greater area to simulate the formation of carbonaceous aerosol during a summer (July 2009) and a winter (January/February 2010) period as part of the MEGAPOLI (megacities: emissions, urban, regional, and global atmospheric pollution and climate effects, and Integrated tools for assessment and mitigation) campaigns. Model predictions of carbonaceous aerosol are compared against Aerodyne aerosol mass spectrometer and black carbon (BC) high time resolution measurements from three ground sites. PMCAMx predicts BC concentrations reasonably well reproducing the majority (70 %) of the hourly data within a factor of two during both periods. The agreement for the summertime secondary organic aerosol (OA) concentrations is also encouraging (mean bias = 0.1 µg m-3) during a photochemically intense period. The model tends to underpredict the summertime primary OA concentrations in the Paris greater area (by approximately 0.8 µg m-3) mainly due to missing primary OA emissions from cooking activities. The total cooking emissions are estimated to be approximately 80 mg d-1 per capita and have a distinct diurnal profile in which 50 % of the daily cooking OA is emitted during lunch time (12:00-14:00 LT) and 20 % during dinner time (20:00-22:00 LT). Results also show a large underestimation of secondary OA in the Paris greater area during wintertime (mean bias = -2.3 µg m-3) pointing towards a secondary OA formation process during low photochemical activity periods that is not simulated in the model.

Evaluating BC and NOx emission inventories for the Paris region from MEGAPOLI aircraft measurements

Science.gov (United States)

Petetin, H.; Beekmann, M.; Colomb, A.; Denier van der Gon, H. A. C.; Dupont, J.-C.; Honoré, C.; Michoud, V.; Morille, Y.; Perrussel, O.; Schwarzenboeck, A.; Sciare, J.; Wiedensohler, A.; Zhang, Q. J.

2015-09-01

High uncertainties affect black carbon (BC) emissions, and, despite its important impact on air pollution and climate, very few BC emissions evaluations are found in the literature. This paper presents a novel approach, based on airborne measurements across the Paris, France, plume, developed in order to evaluate BC and NOx emissions at the scale of a whole agglomeration. The methodology consists in integrating, for each transect, across the plume observed and simulated concentrations above background. This allows for several error sources (e.g., representativeness, chemistry, plume lateral dispersion) to be minimized in the model used. The procedure is applied with the CHIMERE chemistry-transport model to three inventories - the EMEP inventory and the so-called TNO and TNO-MP inventories - over the month of July 2009. Various systematic uncertainty sources both in the model (e.g., boundary layer height, vertical mixing, deposition) and in observations (e.g., BC nature) are discussed and quantified, notably through sensitivity tests. Large uncertainty values are determined in our results, which limits the usefulness of the method to rather strongly erroneous emission inventories. A statistically significant (but moderate) overestimation is obtained for the TNO BC emissions and the EMEP and TNO-MP NOx emissions, as well as for the BC / NOx emission ratio in TNO-MP. The benefit of the airborne approach is discussed through a comparison with the BC / NOx ratio at a ground site in Paris, which additionally suggests a spatially heterogeneous error in BC emissions over the agglomeration.

Unmet healthcare needs in homeless women with children in the Greater Paris area in France.

Directory of Open Access Journals (Sweden)

Cécile Vuillermoz

Full Text Available Despite their poor health status, homeless women encounter many barriers to care. The objectives of our study were to estimate the prevalence of unmet healthcare needs in homeless women and to analyse associated relationships with the following factors: financial and spatial access to care, housing history, migration status, healthcare utilisation, victimization history, caring for children, social network and self-perceived health status.We used data from 656 homeless women interviewed during the ENFAMS representative survey of sheltered homeless families, conducted in the Paris region in 2013. Structural equation models (SEM were used to estimate the impact of various factors on homeless women's unmet healthcare needs.Among those interviewed, 25.1% (95%CI[21.3-29.0] had at least one unmet healthcare need over the previous year. Most had given up on visiting general practitioners and medical specialists. No association with factors related to financial access or to health insurance status was found. However, food insecurity, poor spatial health access and poor self-perceived health were associated with unmet healthcare needs. Self-perceived health appeared to be affected by victimization and depression.The lower prevalence of unmet healthcare needs in homeless women compared with women in stable housing situations suggests that homeless women have lower needs perceptions and/or lower expectations of the healthcare system. This hypothesis is supported by the results from SEM. Strategies to provide better access to care for this population should not only focus on financial interventions but also more broadly on spatial healthcare access, cultural norms, and perceptions of health. Reducing their unmet needs and improving their access to healthcare and prevention must include an improvement in their living, financial and housing conditions.

La propagande anti-britannique en France pendant l’Occupation Anti-British Propaganda in France during the Occupation

Directory of Open Access Journals (Sweden)

Françoise Passera

2009-06-01

Full Text Available Left to fight alone after France signed the armistice on the 22nd of June 1940, Great Britain became enemy number one in the eyes of the German occupying forces and the Vichy government. This hostility found expression in a considerable quantity of propaganda in the guise of posters, tracts, booklets and brochures meant to denounce British responsibility for the conflict in the eyes of French public opinion. Propaganda was particularly intense from June to December 1940 and from January to June 1944 but the German and French propaganda services waged this psychological warfare against Great Britain throughout the war. In 1940, the anti-British brainwashing campaigns aimed at ridding the defeated French of their guilt by accusing the ex-ally of being the cause of the conflict and of deceit during the Battle of France. In 1941-1942, the Allies’ military setbacks were the subject of tracts and brochures that ridiculed British strategic skills. Propaganda was also based on the painful history of France and Great Britain so as to convince the French that England had always tried to deprive France of her colonies and that it was what she was trying to do by maintaining her presence in Africa. The major part of this propaganda was promoted by the German authorities, only to a lesser degree by the French collaboration parties. Till 1942, the Information Secretariat of the Vichy government distributed few anti-British tracts, concentrating its efforts on the promotion of the National Revolution. On the other hand, the first Anglo-American bombings in the Paris area provoked strong reactions in the Vichy government which then relied on the French population’s confusion and anxiety to denounce British policy. What was the impact of these anti-British speeches on the French population? The prefects’ reports on public opinion show that the plugging of Anglophobic sentiment had little influence on the French who were globally in complete support of the

Gas conference Paris 2013

International Nuclear Information System (INIS)

Anon.

2013-01-01

This special issue of Gaz d'Aujourd'hui journal contains the proceedings of the 2013 edition of the annual French gas conference. These proceedings comprise 7 talks, 5 round-tables and 9 workshops: 1 - Opening talk (H. Malherbe); 2 - Defending the natural gas position in the energy mix (G. Mestralet); 3 - The new youth of natural gas (P. Sauquet); 4 - Round-table No.1: the natural gas market perspectives; 5 - Round-table No.2: natural gas in France's energy transition; 6 - Answering the energy transition challenges (B. Lescoeur); 7 - Round-table No.3: towards an integrated European market in 2014?; 8 - Building up the European gas market (P. de Ladoucette); 9 - Workshop No.1: the big client's strategies in the gas market; 10 - Workshop No.2: the fuel gas perspectives in terrestrial mobility; 11 - Workshop No.3: gas innovations; 12 - The 2030 and 2050 strategy of the European Union policy (B. Devlin); 13 - Round-table No.4: Decentralized production and local development; 14 - Workshop No.4: Gas and maritime transport; 15 - Workshop No.5: bio-methane, vector of the energy transition; 16 - Workshop No.6: Evolution of the storage activity; 17 - Workshop No.7: Dwellings renovation and natural gas development; 18 - Workshop No.8: Is the target model of gas a reality?; 19 - Workshop No.9: Non-conventional gases in the world; 20 - Round-table No.5: Actors' strategy; 21 - Closing talk (J. Ferrier)

PINK1 Primes Parkin-Mediated Ubiquitination of PARIS in Dopaminergic Neuronal Survival

Directory of Open Access Journals (Sweden)

Yunjong Lee

2017-01-01

Full Text Available Mutations in PTEN-induced putative kinase 1 (PINK1 and parkin cause autosomal-recessive Parkinson’s disease through a common pathway involving mitochondrial quality control. Parkin inactivation leads to accumulation of the parkin interacting substrate (PARIS, ZNF746 that plays an important role in dopamine cell loss through repression of proliferator-activated receptor gamma coactivator-1-alpha (PGC-1α promoter activity. Here, we show that PARIS links PINK1 and parkin in a common pathway that regulates dopaminergic neuron survival. PINK1 interacts with and phosphorylates serines 322 and 613 of PARIS to control its ubiquitination and clearance by parkin. PINK1 phosphorylation of PARIS alleviates PARIS toxicity, as well as repression of PGC-1α promoter activity. Conditional knockdown of PINK1 in adult mouse brains leads to a progressive loss of dopaminergic neurons in the substantia nigra that is dependent on PARIS. Altogether, these results uncover a function of PINK1 to direct parkin-PARIS-regulated PGC-1α expression and dopaminergic neuronal survival.

France country report

Energy Technology Data Exchange (ETDEWEB)

Mouillot, Dominique [Onet Technologies, 36, Bd des Oceans 13009 Marseille (France)

2008-07-01

Nuclear in France - Electricity share: 78%. Electricity production by Electricite de France: 419 TWh, 63,260 GWe installed. Number of Reactors: 58 NPPs type PWR (Pressurized Water Reactor) in operation; One under construction: EPR (European Pressurized Reactor) Flamanville 3, on time. Others nuclear installations: The AREVA NC La Hague fuel treatment and recycling plant - Capacity: 1700 tons (Facilities UP2 and UP3). COMURHEX is number one worldwide in the conversion of uranium mine concentrates into UF{sub 6} and has a processing capacity of 14,000 tonnes of uranium per year. EURODIF Production site, with the construction of the Georges Besse II plant, Centrifugation is the highest performance technology today. Others nuclear installations: MELOX production site - Mox fuel production; FBFC:fuel rods manufacturing; Waste Storage in Surface and Subsurface: The Aube department storage center in Soulaines, which houses short-lived low- to medium-level waste; the VLL storage centre in Morvilliers (Aube), which houses very low-level waste. Public acceptance: An opinion poll published in June 2007, commissioned by the OE (Observatoire de l'Energie) shows that a majority of French people support nuclear. The respondents were asked whether nuclear energy, which produces 78% of total electricity, is an asset: 51% of them backed the idea, 39% a disadvantage, 10% did not have an opinion. Energy policy: The new President Nicolas Sarkozy said that Nuclear energy is necessary for France. (Organisation of so called 'Grenelle of environment'). Projects: EPR Flamanville 3: Due to be commissioned in 2012, Commercial FBR (Fast Breeders reactor) in 2040, EURODIF will ended in 2012 and Georges Besse 2 (centrifugation) should be operational in 2012, Decommissioning of 6 UNGG reactors, Superphenix and Brennillis within 25 years. (estimated at 3 billion Euros). Nuclear waste management policy: The French National Radioactive Waste Management Agency (ANDRA) is responsible

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Indian Academy of Sciences (India)

1Faculty of Humanities and Social Sciences, University of Rijeka, 51000 Rijeka, Croatia. 2Astronomical Observatory, Volgina 7, 11060 Belgrade, Serbia. 3LERMA, Observatoire de Paris, PSL Research University, CNRS, Sorbonne Universities,. UPMC Univ. Paris 06, 5 Place Jules Janssen, 92195 Meudon Cedex, France.

Paris-Princeton Lectures on Mathematical Finance

CERN Document Server

Carmona, René A; Kohatsu-Higa, Arturo; Lasry, Jean-Michel; Lions, Pierre-Louis; Pham, Huyên; Taflin, Erik

2007-01-01

The Paris-Princeton Lectures in Financial Mathematics, of which this is the third volume, will, on an annual basis, publish cutting-edge research in self-contained, expository articles from outstanding - established or upcoming! - specialists. The aim is to produce a series of articles that can serve as an introductory reference for research in the field. It arises as a result of frequent exchanges between the finance and financial mathematics groups in Paris and Princeton. The present volume sets standards with articles by René Carmona, Ivar Ekeland/Erik Taflin, Arturo Kohatsu-Higa, Pierre-Louis Lions/Jean-Michel Lasry, and Hyuên Pham.

Application of the Best Available Technique (BAT) in Swedish Nuclear Industry: Ringhals and Barsebaeck Nuclear Power Plants. Report to the Oslo and Paris Commissions in accordance with PARCOM Recommendation 91/4

International Nuclear Information System (INIS)

1996-01-01

With regard to the general objectives of the Paris Convention, contracting parties have agreed, as stated in PARCOM Recommendation 91/4, to apply best available technique (BAT) to reduce radioactive releases from the nuclear industry. Progress in implementing BAT shall be reported to the Oslo and Paris Commissions every four years. This report contains the Swedish submission for the second round of implementation reports. Data are provided relevant to the Ringhals NPP, which discharged into Convention waters, and - for information -the Barsebaeck NPP which discharged into waters close to the Convention area. 20 tabs

Application of the Best Available Technique (BAT) in Swedish Nuclear Industry: Ringhals and Barsebaeck Nuclear Power Plants. Report to the Oslo and Paris Commissions in accordance with PARCOM Recommendation 91/4

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-01-01

With regard to the general objectives of the Paris Convention, contracting parties have agreed, as stated in PARCOM Recommendation 91/4, to apply best available technique (BAT) to reduce radioactive releases from the nuclear industry. Progress in implementing BAT shall be reported to the Oslo and Paris Commissions every four years. This report contains the Swedish submission for the second round of implementation reports. Data are provided relevant to the Ringhals NPP, which discharged into Convention waters, and - for information -the Barsebaeck NPP which discharged into waters close to the Convention area. 20 tabs.

Judging the Paris Agreement: A comparison with IDDRI's 10 criteria for success

International Nuclear Information System (INIS)

Deprez, Alexandra; Spencer, Thomas

2016-03-01

The Paris Agreement is universal, legally binding and differentiated. (1) It was adopted by consensus by 195 countries, implying a very strong level of global buy-in. (2) It meets the requirements for a treaty under international law, and imposes obligations upon countries regarding NDCs (submission, implementation, transparency). (3) It does not establish new Annexes (cf. Kyoto Protocol) but rather nuances countries' obligations across each of Agreement's elements (i.e. mitigation, adaptation, support), at times specifying differing obligations in line with countries' different national circumstances. The Paris Agreement is ambitious. (4) It reaffirms the goal of maintaining global temperature rise to below 2 deg. C, and operationalizes this target by establishing a goal to achieve net-zero global emissions between 2050 and 2100. It also calls for an aspirational goal of maintaining temperature under 1.5 deg. C. (5) It includes the concept of cycles, whereby countries will regularly revise their national climate ambition upward in a coordinated manner, (8) and an overarching financial objective, strongly signaling to business and investors countries' commitment toward a low-carbon future. (9) Finally, it establishes a single, unified but flexible transparency system for all countries. The Paris Agreement sets up a framework for action beyond mitigation and the UNFCCC. (6) It establishes an overarching goal on adaptation, which can help create a more 'balanced' climate regime in which mitigation and adaptation share equal footing. (7) Even though the very scientifically, legally and politically complex issues of 'liability' have not yet been fully fleshed out, the inclusion in the Paris outcome of a full article on loss and damage is more than many expected. (10) The maintaining of Non-State Actor Zone for Climate (NAZCA) platform created at COP20 to track non-state actors' initiatives shows that the UNFCCC, while remaining the center for state action, aims to help

PARIS II: Computer Aided Solvent Design for Pollution Prevention

Science.gov (United States)

This product is a summary of U.S. EPA researchers' work developing the solvent substitution software tool PARIS II (Program for Assisting the Replacement of Industrial Solvents, version 2.0). PARIS II finds less toxic solvents or solvent mixtures to replace more toxic solvents co...

Using the Bergman-Paris Question to screen seniors in the emergency department.

Science.gov (United States)

Lague, Antoine; Voyer, Philippe; Ouellet, Marie-Christine; Boucher, Vale Rie; Giroux, Marianne; Pelletier, Mathieu; Gouin, E Milie; Daoust, Raoul; Berthelot, Simon; Morin, Miche le; Minh Vu, Thien Tuong; Lee, Jacques; Brousseau, Audrey-Anne; Sirois, Marie-Jose E; E Mond, Marcel

2017-10-16

In the fast pace of the Emergency Department (ED), clinicians are in need of tailored screening tools to detect seniors who are at risk of adverse outcomes. We aimed to explore the usefulness of the Bergman-Paris Question (BPQ) to expose potential undetected geriatric syndromes in community-living seniors presenting to the ED. This is a planned sub-study of the INDEED multicentre prospective cohort study, including independent or semi-independent seniors (≥65 years old) admitted to hospital after an ED stay ≥8 hours and who were not delirious. Patients were assessed using validated screening tests for 3 geriatric syndromes: cognitive and functional impairment, and frailty. The BPQ was asked upon availability of a relative at enrolment. BPQ's sensitivity and specificity analyses were used to ascertain outcomes. A response to the BPQ was available for 171 patients (47% of the main study's cohort). Of this number, 75.4% were positive (suggesting impairment), and 24.6% were negative. To detect one of the three geriatric syndromes, the BPQ had a sensitivity of 85.4% (95% CI [76.3, 92.0]) and a specificity of 35.4% (95% CI [25.1, 46.7]). Similar results were obtained for each separate outcome. Odds ratio demonstrated a higher risk of presence of geriatric syndromes. The Bergman-Paris Question could be an ED screening tool for possible geriatric syndrome. A positive BPQ should prompt the need of further investigations and a negative BPQ possibly warrants no further action. More research is needed to validate the usefulness of the BPQ for day-to-day geriatric screening by ED professionals or geriatricians.

VISAS FOR FRANCE

CERN Multimedia

Relations with the Host States Service

2002-01-01

1. Definition of a visa A visa is an administrative document required by the nationals of certain countries to cross a border. The visas referred to in this article ('consular visas') are issued to people who do not live in France (not to be confused with 'exit and/or re-entry visas' issued to people living in France; cf. communiqué of 26 May 1998, ref. CERN/DSU-DO/RH/8283). 2. Types of visa The numerous types of visa include, in particular: short-stay visas, which allow their holders to enter France for a continuous or non-continuous period not exceeding three months in any six; long-stay visas, which are required by those applying for a residence document (Carte spéciale issued by the French Ministry of Foreign Affairs or Carte de séjour issued by a Préfecture). 3. Visa requirement 3.1 General rule In France, the requirement to obtain a visa varies, in particular, according to nationality and the length of stay. To put it simply, three different situations can...

Current state of exploitation of low enthalpy geothermal energy in France

International Nuclear Information System (INIS)

Boisdet, A.; Fouillac, C.; Jaudin, F.; Menjoz, A.; Rojas, J.; Ferrandes, R.; Lemale, J.

1990-01-01

This paper reports that at present, the geothermal exploitation in France is characterized by sixty plants using geothermal energy for direct heat in district heating. Drilling and connection to networks occurred mainly during the years 1980-1985. From 1985 to 1990, the research efforts have been focused on detailed reservoir knowledge, corrosion-scaling process induced by the fluid composition, methods and techniques for maintenance, rehabilitation of some wells and equipments after work over. Concentrated in two main area, the Paris and Aquitaine basins, the French geothermal potential is large. The improved knowledge obtained during the last five years spared to the valorization of existing plants will allow a new start of geothermal exploitation. Nevertheless this latter is highly dependent on the international energy context

Spall Strength of Tungsten Carbide

Science.gov (United States)

2004-09-01

1 PCS GROUP CAVENDISH LABORATORY W G PROUD MADINGLEY RD CAMBRIDGE UNITED KINGDOM 1 CENTRE D ETUDES DE GRAMAT J Y TRANCHET...46500 GRAMAT FRANCE 1 MINISTERE DE LA DEFENSE DR G BRAULT DGA DSP STTC 4 RUE DE LA PORTE DISSY 75015 PARIS FRANCE 1 SPART

Pariisi kord = Paris' move / João Francisco Figueira

Index Scriptorium Estoniae

Figueira, João Francisco, 1968-

2009-01-01

Pariisi nõustamisprojektide rahvusvahelisest võistlusest "Le Grand Pari(s)". Sooviti saada julget ja elluviidavat projekti Pariisi arenguks aastani 2050. Osales kümme kutsutud arhitektide, planeerijate ja ekspertide töörühma. Osade tööde mõningaid aspekte tutvustav käsitlus

France under a microscope - Nuclear power in France

International Nuclear Information System (INIS)

2008-01-01

The first French nuclear power plant was built in 1956, but it was only after the 1970's oil shock that nuclear power gained an important place in the French energy sector. Planning Act 2005-781 of 13 July 2005 laying down French energy policy orientations confirmed that nuclear energy was to remain the primary source of electricity supply in France. The Act also encourages diversification of sources of electricity production through renewable energies (wind power, biomass) and the security of electricity supply from oil, gas and coal. Nuclear energy accounted for 78.4% of electricity production in France in 2006. French nuclear capacity includes 58 pressurized water reactors (PWRs) that produced 450 billion nuclear kilowatt-hours (kWh) in 2006, i.e. 78.4% of total electricity production which is of 574 billion kWh. The lifetime of a third of currently operating nuclear plants will end in around 2020 and, with a view to the renewal of its nuclear capacity, France is about to deploy new-generation reactors that meet requirements in terms of production, environmental protection and enhanced nuclear safety. In April 2007, France started building a third-generation EPR reactor at Flamanville in the Manche Department. The EPR is to be operational by 2012. France is also devoting research programmes to fourth generation reactor technology with a view to those reactors being operational by 2040. There are a number of reasons for choosing nuclear power: it enables France to ensure its national energy independence (France imports less than 50% of its energy resources) and environmental protection (France is one of the European countries which emits the least greenhouse gases) at a stable and competitive price. Decree 2008-378 of 21 April 2008 instituted a council on nuclear policy presided by the President of the Republic. The council will define the broad lines of nuclear policy and monitor their implementation, particularly with regard to exports and international

Conditions for a market uptake of climate services for adaptation in France

Directory of Open Access Journals (Sweden)

Romain Cavelier

2017-04-01

Full Text Available This perspective paper reports the results of a collaborative survey of French research institutes concerned with environmental issues, which examined the potential for a market uptake of climate services for adaptation in France. The study is based on a review of existing reports on the market of climate services, and on interviews of 68 climate service providers and users in public and private organizations. Although the study does not allow to provide quantified estimations regarding the present and future size of the market, its results offer new perspectives with implications extending far beyond the sole case of France: first, while the market is still in its infancy, significant opportunities exist in sectors such as flooding risks, and, to a slightly lesser extent, hydro and nuclear energy and viticulture. In addition, the study identifies critical conditions for the uptake in climate services: (1 a coordinated delivery of data, information, expertise and training by public research institutes concerned with climate change and its impacts; (2 the inclusion of adaptation in the regulation and in public and private tenders. Finally, (3 uncertainties in climate projections appear as a major barrier to the uptake of climate services. However, ambitious greenhouse gas emission reduction as planned by the COP-21 Paris Agreement contribute to reducing this uncertainties by allowing users to select a subset of climate change projections, avoiding those for which adaptation is most problematic.

Enterovirus infections in hospitals of Ile de France region over 2013.

Science.gov (United States)

Molet, Lucie; Saloum, Kenda; Marque-Juillet, Stéphanie; Garbarg-Chenon, Antoine; Henquell, Cécile; Schuffenecker, Isabelle; Peigue-Lafeuille, Hélène; Rozenberg, Flore; Mirand, Audrey

2016-01-01

The monitoring and genotyping of Enterovirus (EV) infections can help to associate particular or severe clinical manifestations with specific EV types and to identify the aetiology of infectious outbreaks. To describe the epidemiological features of EV infections diagnosed during the year 2013 in the Greater Paris area (Ile de France). During 2013, 2497 samples taken from 470 patients in 33 hospitals of Ile-de France were tested for EV genome by RT-PCR. EV genotyping was performed by the National Reference Centre (NRC) laboratories. EV infections were retrospectively reviewed by retrieving clinical and genotyping data from the NRC database. Of the 2497 samples, 490 (19.6%) was positive for EV genome detection. These EV infections represented 88.7% and 24.1%, respectively, of all reported regional and national infections. Twenty-seven different genotypes were identified. Echovirus 30 (E-30) accounted for 54.1% of all characterized strains and caused a large outbreak. Four severe neonatal infections were reported, of which two were caused by EV-A71. Respiratory infections involving EV-D68 were observed in two adults. One fatal case of Coxsackievirus A2-associated myocarditis was reported. Monitoring EV infections in combination with EV genotyping via the French EV network characterized the epidemiology of EV infections in the Ile de France region in 2013 and documented severe EV infections associated with EV-A71 or CV-A2. Copyright © 2015 Elsevier B.V. All rights reserved.

Submicron aerosol source apportionment of wintertime pollution in Paris, France by double positive matrix factorization (PMF2) using an aerosol chemical speciation monitor (ACSM) and a multi-wavelength Aethalometer

International Nuclear Information System (INIS)

Petit, J.E.; Favez, O.; Leoz-Garziandia, E.; Sciare, J.

2014-01-01

Online non-refractory submicron aerosol mass spectrometer (AMS) measurements in urban areas have successfully allowed the apportionment of specific sources and/or physical and chemical properties of the organic fraction. However, in order to be fully representative of PM pollution, a comprehensive source apportionment analysis is needed by taking into account all major components of submicron aerosols, creating strengthened bonds between the organic components and pollution sources. We present here a novel two-step methodology to perform such an analysis, by taking advantage of high time resolution of monitoring instruments: the aerosol chemical speciation monitor (ACSM) and the multi-wavelength absorption measurements (Aethalometer AE31) in Paris, France. As a first step, organic aerosols (OA) were de-convolved to hydrocarbon-like OA (HOA), biomass burning OA (BBOA) and oxygenated OA (OOA) with positive matrix factorization (PMF), and black carbon was de-convolved into its wood burning and fossil fuel combustion fractions. A second PMF analysis was then carried out with organic factors, BC fractions and inorganic species (nitrate, sulfate, ammonium, chloride), leading to a four-factor solution allowing highly time-resolved characterization of the major sources of PM1. Outputs of this PMF2 include two dominant combustion sources (wood burning and traffic) as well as semi-volatile and low-volatile secondary aerosols. While HOA is found to be emitted by both wood burning and traffic, the latter sources occurred to significantly contribute also to OOA. (authors)

New steroidal saponins from the rhizomes of Paris delavayi and their cytotoxicity.

Science.gov (United States)

Liu, Yang; Tian, Xiangrong; Hua, Dong; Cheng, Guang; Wang, Kaixing; Zhang, Lihan; Tang, Haifeng; Wang, Minchang

2016-06-01

Four new furostanol saponins, named padelaosides C-F (1-4), together with four known spirostanol saponins 5-8 were isolated from the rhizomes of Paris delavayi Franchet. Their structures were elucidated on the basis of extensive spectroscopic analysis and chemical evidences. The discovery of the new compounds 1-4 extended the diversity and complexity of this furostanol saponin family. The cytotoxicity of all the saponins was evaluated for their cytotoxicity against human glioblastoma U87MG and human hepatocellular carcinoma Hep-G2 cell lines. The known spirostanol saponins 7 and 8 exhibited notable cytotoxicity against the two tumor cell lines with IC50 values of 1.13 and 3.42μM, respectively, while the new furostanol saponins 3 and 4 showed moderate cytotoxicity with IC50 values of 15.28 to 16.98μM. Copyright © 2016 Elsevier B.V. All rights reserved.

Post Paris and November 8, 2016

Science.gov (United States)

Busalacchi, A. J.

2016-12-01

COP 21 in Paris, as historic as it was, established the necessary, but not the sufficient. The signatories to the landmark Paris accord are a coalition of the willing, but their pledges are only as good as the sustained will of individual countries to adhere to their commitments. The U.S. presidential election has demonstrated how easily uncertainty can be added. Even if all countries abide by the Paris climate agreement, capping global mean temperatures to 2oC will likely require net zero greenhouse gas emissions by 2085 and substantial negative emissions over the long term. Before the Paris agreement was finished, it was clear that the pledged emission cuts by 2030 would not be sufficient in and of themselves, to stay under 2oC. Given the accumulation of greenhouse gases to date, limiting warming to a maximum of 2oC would require bending the curve of global emissions by 2020, i.e., over the next four years. If the past is a prologue, without even taking into account an emergence from the global recession, we stand a realistic chance of blowing right past the 2oC target. What, then, are the challenges going forward? Is 2oC a real goal that is attainable, or is it a stretch goal? Meeting a 2oC target is a function of when mitigation begins in earnest, the rate of mitigation, and the rate and amount of carbon sequestration. What are the implications of this trade space? While much effort has been put into designing a climate observing system from a science perspective, relatively little thought has been put into determining what observations are needed to support policy decisions, mitigation, and verify the Intended Nationally Determined Contributions that resulted from the Paris Agreement. If 2oC is a stretch goal, intellectual honesty requires that we consider mitigation and adaptation in tandem, and not as either/or. Similarly, even with all its attendant ethical dilemmas, it is important to thoroughly study geoengineering so that policy makers have a robust

Impacts of Climate Change and of Anthropisation on Water Resources: from the Risk Assessment to Adaptation, the Case of the Seine Basin (including Paris, France)

Science.gov (United States)

Habets, F.; Viennot, P.; Thierion, C.; Vergnes, J. P.; Ait Kaci, A.; Caballero, Y.

2015-12-01

The Seine river, located in the temperate climate of northern France and flowing over a large sedimentary basins that hosts multilayer aquifers, is characterized by small temporal variations of its discharge. However, the presence of a megacity (Paris) and a wide area of intensive agriculture combined with climate change puts pressure on the water resources both in terms of quality and quantity. Previous research projects have estimated the impact of climate change on the water resource of the Seine basin, with the uncertainties associated to climate projections, hydrological models or downscaling methods. The water resource was projected to decrease by -14 % ± 10 % in 2050 and -28 +/-16% in 2100. This led to new studies that focus on the combined impact of climate change and adaptations. The tested adaptations are: a reduction of the groundwater abstractions, evolution of land use, development of small dams to « harvest water » or artificial recharge of aquifers. The communication of the results of these projects to stakeholders have led to the development on new indicators that better express the risk on the water resource management, especially for the groundwater. For instance maps of the evolution of piezometric head are difficult to interpret. To better express the risk evolution, a new indicator was defined: the evolution of the groundwater crisis duration, ie, the period when the charge of the aquifer is below the crisis piezometric level defined by the stakeholders. Such crisis piezometric levels are used to help defining the period when the groundwater abstraction should be reduced. Such maps are more efficient to communicate with water resources managers. This communication will focus on the results from the MEDDE Explore 2070 and ANR Oracle projects.

Regulation in the face of uncertainty: the evidence on electronic nicotine delivery systems (e-cigarettes)

OpenAIRE

Farsalinos, Konstantinos E; Le Houezec, Jacques

2015-01-01

Konstantinos E Farsalinos,1,2 Jacques Le Houezec3,4 1Department of Cardiology, Onassis Cardiac Surgery Center, Kallithea, 2Department of Pharmacy, University of Patras, Patras, Greece; 3Division of Epidemiology and Public Health, UK Centre for Tobacco and Alcohol Studies, University of Nottingham, Nottingham, England, UK; 4Addiction Research Unit, INSERM 1178 (Mental and Public Health), Paris, France Abstract: Tobacco smoking is the largest single preventable cause of many chronic diseases a...

Facial skin pores: a multiethnic study

OpenAIRE

Flament, Frederic; Francois,Ghislain; Qiu,Huixia; Ye,Chengda; Hanaya,Tomoo; Batisse,Dominique; Cointereau-Chardon,Suzy; Seixas,Mirela Donato Gianeti; Dal Belo,Susi Elaine; Bazin,Roland

2015-01-01

Frederic Flament,1 Ghislain Francois,1 Huixia Qiu,2 Chengda Ye,2 Tomoo Hanaya,3 Dominique Batisse,3 Suzy Cointereau-Chardon,1 Mirela Donato Gianeti Seixas,4 Susi Elaine Dal Belo,4 Roland Bazin5 1Department of Applied Research and Development, L’Oreal Research and Innovation, Paris, France; 2Department of Applied Research and Development, L’Oreal Research and Innovation, Shanghai, People’s Republic of China; 3Department of Applied Research and Development, L&r...

Comparison of the energy stakes of France and Germany

International Nuclear Information System (INIS)

2013-01-01

In view of the first French-German conference of July 2 2013, held in Paris, this paper presents the energy situation of both countries with their perspectives of evolution: 1 - the emergence of a French-German bilateral cooperation in the energy domain; 2 - the economical and energetic situation of both countries; 3-4 - a fundamental structural difference: the demographic evolution.. which is susceptible to directly impact the long-term growth; 5 - impacts on the energy intensity trends of both countries; 6 - consequences on the achievement of the 'Factor 4' goal

The Chinese Diaspora: China’s Instrument of Power

Science.gov (United States)

2010-06-01

University Press, 2007. Bergère, Marie-Claire. L’âge d’or de la bourgeoisie chinoise 1911-1937. Paris, France : Flammarion, 1986. Biao, Xiang...in Marie- Claire Bergère, L’âge d’or de la bourgeoisie chinoise 1911-1937, (Paris, France : Flammarion,1986), 46. 121 Akin to slaves...communautés chinoises d’outre-mer. Paris, France : L’Harmattan, 1997. Puel, Caroline. ―Quand le monde parlera chinois.‖ LE POINT SPÉCIAL CHINE, 25

Patterns of post-acute health care utilization after a severe traumatic brain injury: Results from the PariS-TBI cohort.

Science.gov (United States)

Jourdan, Claire; Bayen, Eleonore; Darnoux, Emmanuelle; Ghout, Idir; Azerad, Sylvie; Ruet, Alexis; Vallat-Azouvi, Claire; Pradat-Diehl, Pascale; Aegerter, Philippe; Weiss, Jean-Jacques; Azouvi, Philippe

2015-01-01

To assess brain injury services utilization and their determinants using Andersen's model. Prospective follow-up of the PariS-TBI inception cohort. Out of 504 adults with severe traumatic brain injury (TBI), 245 survived and 147 received a 4-year outcome assessment (mean age 33 years, 80% men). Provision rates of medical, rehabilitation, social and re-entry services and their relations to patients' characteristics were assessed. Following acute care discharge, 78% of patients received physiotherapy, 61% speech/cognitive therapy, 50% occupational therapy, 41% psychological assistance, 63% specialized medical follow-up, 21% community re-entry assistance. Health-related need factors, in terms of TBI severity, were the main predictors of services. Provision of each therapy was significantly associated with corresponding speech, motor and psychological impairments. However, care provision did not depend on cognitive impairments and cognitive therapy was related to pre-disposing and geographical factors. Community re-entry assistance was provided to younger and more independent patients. These quantitative findings illustrate strengths and weaknesses of late brain injury care provision in urban France and highlight the need to improve treatment of cognitive impairments.

Proceedings of the second workshop of LHC Computing Grid, LCG-France; ACTES, 2e colloque LCG-France

Energy Technology Data Exchange (ETDEWEB)

Chollet, Frederique; Hernandez, Fabio; Malek, Fairouz; Gaelle, Shifrin (eds.) [Laboratoire de Physique Corpusculaire Clermont-Ferrand, Campus des Cezeaux, 24, avenue des Landais, Clermont-Ferrand (France)

2007-03-15

The second LCG-France Workshop was held in Clermont-Ferrand on 14-15 March 2007. These sessions organized by IN2P3 and DAPNIA were attended by around 70 participants working with the Computing Grid of LHC in France. The workshop was a opportunity of exchanges of information between the French and foreign site representatives on one side and delegates of experiments on the other side. The event allowed enlightening the place of LHC Computing Task within the frame of W-LCG world project, the undergoing actions and the prospects in 2007 and beyond. The following communications were presented: 1. The current status of the LHC computation in France; 2.The LHC Grid infrastructure in France and associated resources; 3.Commissioning of Tier 1; 4.The sites of Tier-2s and Tier-3s; 5.Computing in ALICE experiment; 6.Computing in ATLAS experiment; 7.Computing in the CMS experiments; 8.Computing in the LHCb experiments; 9.Management and operation of computing grids; 10.'The VOs talk to sites'; 11.Peculiarities of ATLAS; 12.Peculiarities of CMS and ALICE; 13.Peculiarities of LHCb; 14.'The sites talk to VOs'; 15. Worldwide operation of Grid; 16.Following-up the Grid jobs; 17.Surveillance and managing the failures; 18. Job scheduling and tuning; 19.Managing the site infrastructure; 20.LCG-France communications; 21.Managing the Grid data; 22.Pointing the net infrastructure and site storage. 23.ALICE bulk transfers; 24.ATLAS bulk transfers; 25.CMS bulk transfers; 26. LHCb bulk transfers; 27.Access to LHCb data; 28.Access to CMS data; 29.Access to ATLAS data; 30.Access to ALICE data; 31.Data analysis centers; 32.D0 Analysis Farm; 33.Some CMS grid analyses; 34.PROOF; 35.Distributed analysis using GANGA; 36.T2 set-up for end-users. In their concluding remarks Fairouz Malek and Dominique Pallin stressed that the current workshop was more close to users while the tasks for tightening the links between the sites and the experiments were definitely achieved. The IN2P3

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Indian Academy of Sciences (India)

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Serge Haroche, Collège de France, Paris, France, École Normale Supérieure, Paris, France. David J Wineland, National Institute of Standards and Technology, Boulder, CO, USA; Univer- sity of Colorado, Boulder, CO, USA. Chemistry. “for studies of G-protein-coupled receptors” to. Robert J Lefkowitz, Howard Hughes ...

Quantitative impact of the recent abatement of air pollution on the weathering of stone and glass of the UNESCO List in Paris

Science.gov (United States)

Lefèvre, Roger; Ionescu, Anda; Desplat, Julien; Kounkou-Arnaud, Raphaëlle; Perrussel, Olivier; Languille, Baptiste

2016-04-01

Quantitative impact of the recent abatement of air pollution on the weathering of stone and glass of the UNESCO List in Paris R.-A. Lefèvre1, A. Ionescu1, J. Desplat2, R. Kounkou-Arnaud2, O. Perrussel3, B. Languille4 At the beginning of the 21st century air pollution in Paris continued to considerably decrease. An evident visual consequence was the replacement of thick gypseous black crusts by thin grey coverings on the façades. A quantitative approach of this phenomenon was taken by measurement in the field, followed by calculation using Dose-Response Functions (DRF) and mapping the geographic distribution on a grid of 100m x100m of: 1) The total surface of façades of buildings and monuments in the part of Paris inscribed on the UNESCO List between the Ile Saint-Louis and the Concorde Square; 2) The surface of limestone and window glass present on each façade; 3) The distribution of SO2, NO2 and PM10 concentration every year from 1997 to 2014; 4) The response of materials to climatic and pollution doses; 5) The effective damage to limestone and window glass. Results of measurements in the field: 1) The 772 buildings and monuments inventoried have 20 674 m in length and 414 811 m2 in façade surface: they are representative of the centre of Paris; 2) Limestone occupies 348 268 m2 and window glass 207 394 m2; 3) The mean annual concentration in SO2 dropped from 20 to less than 3 μg m-3; NO2 from 60 to 40 μg m-3 and PM10 from 30 to 20 μg m-3. Results by application of DRF: 4) Limestone recession was divided by 5 in 18 years, from 10 to 2 μm y-1, but with only a spatial variation of 2%; 5) Limestone reflectance increased from 70.5 to 72.5 %; 6) The annual mass of deposited and neo-formed particles on window glass decreased from 100 to 20 μg cm-2; 7) The annual haze of window glass decreased from 8 to 3.5%. Effective damage to stone and glass: 8) The mean annual mass of limestone eroded on the façades decreased according to time but with an irregular

Patient survey to identify reasons for non-adherence and elicitation of quality of life concepts associated with immunosuppressant therapy in kidney transplant recipients

OpenAIRE

Muduma, Gorden; Shupo, Francis C; Dam, Sophie; Hawken, Natalia A; Aball?a, Samuel; Odeyemi, Isaac; Toumi, Mondher

2016-01-01

Gorden Muduma,1 Francis C Shupo,2 Sophie Dam,3 Natalia A Hawken,3 Samuel Aballéa,3 Isaac Odeyemi,1 Mondher Toumi4 1Astellas Pharma Europe Ltd, Chertsey, 2Creativ-Ceutical Ltd, London, UK; 3Creativ-Ceutical Ltd, Paris, 4Public Health (EA 3279), Faculty of Medicine, Aix-Marseille University, Marseille, France Background: Renal transplantation (RT) is considered the treatment of choice for end-stage renal disease compared to dialysis, offering better health-related quality of life (...

Environmental concern and the political process in France: Patterns of the 1981 elections

International Nuclear Information System (INIS)

McDonald, J.R.

1982-01-01

The environment as a political cause emerged on the national scene in France in 1978, when the ''green'' party captured an impressive share of the initial parliamentary vote. In the presidential election of April, 1981, the environmental candidate ran moderately well, polling over one million votes and leading all other minority and special interest party candidates. In subsequent parliamentary elections (June, 1981), however, ''green'' candidates attracted only about half of their 1978 support, a decline attributable largely to the success of socialist candidates. Despite this setback, it is possible to identify persistent areas of strong environmental electoral support in Alsace, the Paris metropolitan area, the Rhone-Alpes region, and to a lesser extent lower Normandy and Brittany

A need for evidence-based clinical practice guidelines for the use of heparins in the elderly

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Isabelle Gouin-Thibault

2010-04-01

Full Text Available Isabelle Gouin-Thibault1,2, Virginie Siguret1,2, Eric Pautas2,31Assistance Publique Hôpitaux de Paris, Laboratoire d’Hématologie, Hôpital Charles Foix, Paris, France; 2Université Paris Descartes, INSERM U, Paris, France; 3Assistance Publique Hôpitaux de Paris, Unité de Gériatrie Aiguë, Hôpital Charles Foix, Paris, FranceAbstract: Low-molecular-weight heparins (LMWHs have been widely studied in pivotal clinical trials or in several meta-analyses. However, the safety and optimal use of LMWHs in high-risk patients such as the very elderly remains uncertain since these patients are usually excluded from clinical trials. In terms of LMWHs in the elderly, the main concerns are renal failure and the risk of accumulation. A clinical approach consisting of a LMWH dose reduction in the elderly should be considered with great caution in terms of efficacy, since it has been tested neither in the treatment of VTE nor in VTE prophylaxis. If monitoring is considered in patients receiving therapeutic dose LMWHs, appropriate target ranges for peak anti-Xa activity levels should be used and so far, no anti-Xa activity-based guidelines have been issued. Moreover, no data support any laboratory monitoring in elderly patients treated with prophylactic dose LMWHs.Keywords: elderly patients, low-molecular-weight heparin, renal insufficiency, evidence-based medicine

Nutrition Transition and Biocultural Determinants of Obesity among Cameroonian Migrants in Urban Cameroon and France.

Science.gov (United States)

Cohen, Emmanuel; Amougou, Norbert; Ponty, Amandine; Loinger-Beck, Juliette; Nkuintchua, Téodyl; Monteillet, Nicolas; Bernard, Jonathan Y; Saïd-Mohamed, Rihlat; Holdsworth, Michelle; Pasquet, Patrick

2017-06-29

Native of rural West Cameroon, the Bamiléké population is traditionally predisposed to obesity. Bamiléké who migrated to urban areas additionally experience the nutrition transition. We investigated the biocultural determinants of obesity in Bamiléké who migrated to urban Cameroon (Yaoundé), or urban France (Paris). We conducted qualitative interviews ( n = 36; 18 men) and a quantitative survey ( n = 627; 266 men) of adults using two-stage sampling strategy, to determine the association of dietary intake, physical activity and body weight norms with obesity of Bamiléké populations in these three socio-ecological areas (rural Cameroon: n = 258; urban Cameroon: n = 319; urban France: n = 50). The Bamiléké valued overweight and traditional energy-dense diets in rural and urban Cameroon. Physical activity levels were lower, consumption of processed energy-dense food was frequent and obesity levels higher in new migrants living in urban Cameroon and France. Female sex, age, duration of residence in urban areas, lower physical activity and valorisation of overweight were independently associated with obesity status. This work argues in favour of local and global health policies that account for the origin and the migration trajectories to prevent obesity in migrants.

Evaluation and monitoring of an household waste incineration plant in Paris area

International Nuclear Information System (INIS)

Person, A.; Le Moullec, Y.; Gilibert, E.

1995-01-01

Urban population is more and more concerned by air quality and waste disposal. In Paris Area, municipal waste are incinerated in three large plants all equipped with gas cleaning systems, except one that will be equipped in June 1995. It appeared interesting to characterize and evaluate the impact of this incinerator on ambient air quality in an area where other sources interfere. An sampling campaign was set up on six sites of AIRPARIF (ile de France Air Quality Monitoring Network). Nitrogen oxides. Sulphur dioxide and black smokes are measured in continuously. Other pollutants, considered more specific of waste incineration plants were analysed on a 24 h-sampling basis (heavy metals, hydrochloride acid, Chlorides). The first results seem to show some trends. Regarding usual pollutants, it appears downwind sites present higher average level that upwind sites. For hydrochloric acid, 24 h. averages are higher when the site was frequently downwind during the day. The size of the data set is small for heavy metals, however it seems that an impact can be detected for Cd and Zn. (author)

Could US mayors achieve the entire US Paris climate target?

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Gurney, K. R.; Huang, J.; Hutchins, M.; Liang, J.

2017-12-01

After the recent US Federal Administration announcement not to adhere to the Paris Accords, 359 mayors (and counting) in the US pledged to maintain their commitments, reducing emissions within their jurisdictions by 26-28% from their 2005 levels by the year 2025. While important, this leaves a large portion of the US landscape, and a large amount of US emissions, outside of the Paris commitment. With Federal US policy looking unlikely to change, could additional effort by US cities overcome the gap in national policy and achieve the equivalent US national Paris commitment? How many cities would be required and how deep would reductions need to be? Up until now, this question could not be reliably resolved due to lack of data at the urban scale. Here, we answer this question with new data - the Vulcan V3.0 FFCO2 emissions data product - through examination of the total US energy related CO2 emissions from cities. We find that the top 500 urban areas in the US could meet the national US commitment to the Paris Accords with a reduction of roughly 30% below their 2015 levels by the year 2025. This is driven by the share of US emissions emanating from cities, particularly the largest cohort. Indeed, as the number of urban areas taking on CO2 reduction targets grows, the less the reduction burden on any individual city. In this presentation, we provide an analysis of US urban CO2 emissions and US climate policy, accounting for varying definitions of urban areas, emitting sectors and the tradeoff between the number of policy-active cities and the CO2 reduction burden.

Paris-Princeton Lectures on Mathematical Finance

CERN Document Server

Çinlar, Erhan; Ekeland, Ivar; Jouini, Elyes; Scheinkman, José; Touzi, Nizar

2004-01-01

The Paris-Princeton Lectures in Financial Mathematics, of which this is the second volume, will, on an annual basis, publish cutting-edge research in self-contained, expository articles from outstanding - established or upcoming! - specialists. The aim is to produce a series of articles that can serve as an introductory reference for research in the field. It arises as a result of frequent exchanges between the finance and financial mathematics groups in Paris and Princeton. This volume presents the following articles: "Hedging of Defaultable Claims" by T. Bielecki, M. Jeanblanc, and M. Rutkowski; "On the Geometry of Interest Rate Models" by T. Björk; "Heterogeneous Beliefs, Speculation and Trading in Financial Markets" by J.A. Scheinkman, and W. Xiong.

Theories of genetics and evolution and the development of medical entomology in France (1900-1939).

Science.gov (United States)

Gachelin, G; Opinel, A

2008-12-01

The development of entomology and medical entomology in France is discussed in the context of the prevalence of Lamarckian ideas concerning heredity and evolution. Lamarckian ideas have greatly influenced research carried out at the Institut Pasteur by Emile Roubaud and more generally in Felix Mesnil's laboratory, as well as research in general entomology at the Museum national d'histoire naturelle. By contrast, it did not influence research and teaching at the Faculté de médecine of Paris or that of physicians more generally including those in overseas Instituts Pasteur, which clearly kept away from theoretical discussion concerning the origin of variations and adaptation in insects of medical interest.

Generation 4 International Forum. 2009 annual report

International Nuclear Information System (INIS)

2009-01-01

This 2009 Annual Report is the third annual report issued by GIF (Generation 4. International Forum). It includes 3 chapters in addition to an introduction plus 4 appendices, as follows. Chapter 2 describes the membership and organization of GIF, the structure of its cooperative research and development arrangements as well as the status of Members' participation in such arrangements. Chapter 3 summarizes GIF research and development plans, activities and achievements during 2009. It highlights the scientific and technical challenges facing the teams developing Generation IV systems and the major milestones towards the development of these systems. It also describes the progress made on the development of methodologies for assessing Generation IV systems with respect to the established goals of GIF. Chapter 4 reviews the cooperation between GIF and other international programs dealing with the development of nuclear energy. Appendix 1 provides an overview on the goals of Generation IV nuclear energy systems and an outline of the main characteristics of the six systems selected for joint development by GIF. Appendix 2 presents the objectives that have been set for the various System Steering Committees and the associated Project Management Boards for the next 5 years. Appendix 3 reproduces the Table of Contents of the Proceedings from the GIF Symposium held in Paris (France) in 2009. Appendix 4 provides a list of abbreviations and acronyms (with the corresponding definitions) which are used in this report or are relevant to GIF activities

High and medium high energy lines in France. The SATURNE case

International Nuclear Information System (INIS)

Milleret, G.

1994-01-01

Located in the Paris area, the SATURNE accelerator produces high energy charged particles: protons, deuterons, helium 3, helium 4, neutrons. The beams, with very flexible characteristics (linear energy transfer, flexible environment, dimension and intensity) for simulation of cosmic particles or high energy accelerator environments, allow for testing various individual or complete components. The various commercial offers and prices are presented. 5 fig., 2 ref

Opening Session [International Conference on Fast Reactors and Related Fuel Cycles: Safe Technologies and Sustainable Scenarios (FR13), Paris, France, March 4-7, 2013

International Nuclear Information System (INIS)

Bigot, Bernard

2013-01-01

In Europe today, the energy supply relies on fossil fuels at over 75% of its primary energy consumption. Worldwide, it is over 82%. Such a massive use of fossil fuels is thus both a threat for the environment, climate and health, and also for our economies. In 2012, for France, fossil fuel imports represent an expense 3 times larger than in 2005, and over 90% of France’s trade deficit. If keeping this current energy mix, we will strongly contribute to a large increase of the risk of climate change, environmental and human health impacts, and their damaging effects. Tackling climate change, environmental and health issues will require the priority use of CO 2 emission free energy sources. Despite Kyoto protocol and many political international statements, the amount of CO 2 emission per year has known a +40% growth from 1990 to 2009, with the correlated increase of temperatures. To ensure a sustainable development, the world needs a sustainable energy supply, which makes a sufficient amount available for everybody at an acceptable price. For all these reasons, the substitution of fossil fuel consumption as soon as possible and as large as possible with CO 2 free energy sources must be our top priority. The corner stone of any sustainable European energy is the reduction of our consumption of fossil fuels with three axes of action relative to the technologies using these fuels: energy savings, improved efficiency, substitution by other technologies which do not use such fuels, as renewable and nuclear energies

The German ''Energiewende''. Evaluation after the Paris-agreement; Die Deutsche Energiewende. Bewertung nach dem Klima-Abkommen von Paris

Energy Technology Data Exchange (ETDEWEB)

Roth, Eike

2016-08-01

The World-Climate-Summit 2016 in Paris agreed to exacerbated goals for climate protection. This paper will scrutinize whether Germany can comply with its Paris-obligations by continuing the ongoing German ''Energiewende''. The result is clear-cut: The German ''Energiewende'' is inadequate. Due to the cap-and-trade system of the EU the '''Energiewende''.

A 3-day regimen with azithromycin 1.5% eyedrops for the treatment of purulent bacterial conjunctivitis in children: efficacy on clinical signs and impact on the burden of illness

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Bremond-Gignac D

2015-04-01

Full Text Available Dominique Bremond-Gignac,1,2 Riadh Messaoud,3 Sihem Lazreg,4 Claude Speeg-Schatz,5 Didier Renault,6 Frédéric Chiambaretta7,8 On behalf of the Azithromycin Pediatric Study Group 1Ophthalmology Department, Centre St Victor, University Hospital of Amiens, Picardie Jules Verne University, Amiens, France; 2CNRS FR3636, Paris V University, France; 3Ophthalmology Department, Tahar Sfar University Hospital, Mahdia, Tunisia; 4Dar El Beida, Blida, Algeria; 5Ophthalmology Department, University Hospital of Strasbourg, Strasbourg, France; 6Laboratoires THÉA, Clermont-Ferrand, France; 7Ophthalmology Department, University Hospital of Clermont-Ferrand, Gabriel Montpied Hospital, Clermont-Ferrand, France; 8EA 7281 R2D2, Auvergne University, Clermont-Ferrand, France Purpose: To compare the efficacy of azithromycin 1.5% versus tobramycin 0.3% eyedrops on clinical ocular signs and symptoms of bacterial conjunctivitis in children and to assess the parents’ satisfaction regarding the dosing regimen.Patients and methods: An international, multicenter, randomized, investigator-masked, controlled clinical trial conducted in children (1 day to 18 years old with bulbar conjunctival hyperemia and purulent discharge. Azithromycin 1.5% was administered as 1 drop twice daily for 3 days, and tobramycin 0.3% as 1 drop every 2 hours for 2 days, then 4 times daily for 5 days.Results: A total of 286 patients (mean age: 3.2 years were enrolled. In children with bacteriologically positive cultures (N=203, azithromycin produced a significantly greater improvement in conjunctival discharge (P<0.01 and a trend (P=0.054 toward improvement in conjunctival hyperemia at day 7 than did tobramycin. Complete resolution of conjunctival discharge was significantly more frequent at day 3 on azithromycin than tobramycin (P=0.005. More parents found azithromycin easier to use (in terms of treatment duration, total number of instillations, instilling drops during the day, and difficulty in

Activities of Gaz de France Group

International Nuclear Information System (INIS)

Anon.

2003-01-01

activities (-2.1%). It also includes internal services (delivery services, notably) for a total of euro 4,957 m, eliminated in consolidation. Growth in net income - Group share (+14.9%): The Group improved its financial performance in 2004. Net income - Group share totalled euro 1,046 m, up 14.9% compared with the 2003 figure (euro 910 m). Return on capital employed (ROCE) rose to 8.4% from 7.5% in 2003 while Return on equity (ROE) increased to 10.1%, up from 9.5% the previous year. Changes in the other financial results are as follows: Earnings before interest, taxes, depreciation, and amortization (EBITDA): EBITDA stands at euro4,093 m, marginally down by euro 41 m (-1%) compared with 2003. Group operating income: Owing to the exceptional provisions and amortization booked for a total of euro448 m, operating income fell to euro 1,598 m in 2004 (-15 %). This reflects the Group's decision to speed up its grey-iron replacement programme, which will be completed at the end of 2007 instead of late 2008, and to provide for the full cost of this work immediately. Cash flow stands at euro 3,418 m, up 7.3% thanks, in particular, to the good performance achieved by the Exploration Production activity. Total investments amount to euro 1,763 m, including euro 983 m devoted to the infrastructures sector in France. Exploration and development investments related to projects managed by the Exploration and Production segment came to a total of euro374 m during the 2004 financial year. In addition, euro156 m were invested in external growth operations, the financial concretization of a number of the projects examined in 2004 - including Distrigaz Sud in Rumania - to be pursued in 2005. All in all, the Group enjoys a solid financial structure: - Shareholders' equity, up +7.5%, has now risen to a total of euro 10,593 m. - Net debt has been trimmed by 14.6% compared with its 2003 level to a total of euro 4,411 m. - Following the implementation on January 1, 2005 of the financial reform of the

Efficacy and cost effectiveness of telemedicine for improving access to care in the Paris region: study protocols for eight trials.

Science.gov (United States)

Charrier, Nathanael; Zarca, Kevin; Durand-Zaleski, Isabelle; Calinaud, Christine

2016-02-08

With the development of information and communication technologies, telemedicine has been proposed as a way to improve patient management by facilitating access to appropriate diagnosis and treatment. The Paris Ile de France Regional Health Agency is currently funding a comprehensive program of telemedicine experiments. This article describes the protocols for the evaluation of the implementation of telemedicine in the Paris region. Over 2,500 patients have been included in eight studies addressing the use of telemedicine in the context of specific diseases or settings. Two projects are randomized controlled trials, while the six other projects are based on before-after designs (differences in differences studies). Based on the MAST model and the French national framework, we identified endpoints to assess the impact of telemedicine on five dimensions: clinical effectiveness, cost-effectiveness, security of the application, patient satisfaction and quality of life and perception of professionals. Telemedicine encompasses a wide range of services and stakeholders, and thus study protocols must be tailored to the specific constraints and interests of the users. NCT02110433 (03/07/2014), NCT02157740 (05/27/2014), NCT02374697 (02/05/2015), NCT02157727 (05/27/2014), NCT02229279 (08/28/2014), NCT02368769 (02/05/2015), NCT02164747 (NCT02164747), NCT02309905 (11/27/2014).

Paris-Princeton lectures on mathematical finance 2002

CERN Document Server

2003-01-01

The Paris-Princeton Lectures in Financial Mathematics, of which this is the first volume, will, on an annual basis, publish cutting-edge research in self-contained, expository articles from outstanding - established or upcoming! - specialists. The aim is to produce a series of articles that can serve as an introductory reference for research in the field. It arises as a result of frequent exchanges between the finance and financial mathematics groups in Paris and Princeton. The present volume sets standards with articles by P. Bank/H. Föllmer, F. Baudoin, L.C.G. Rogers, and M. Soner/N. Touzi.

Bookmaker and pari-mutuel betting

DEFF Research Database (Denmark)

Koch, Alexander; Shing, Hui-Fai

2008-01-01

A widely documented empirical regularity in gambling markets is that bets on high probability events (a race won by a "favourite") have higher expected returns than bets on low probability events (a "longshot" wins). Such favourite-longshot (FL) biases however appear to be more severe and persist......A widely documented empirical regularity in gambling markets is that bets on high probability events (a race won by a "favourite") have higher expected returns than bets on low probability events (a "longshot" wins). Such favourite-longshot (FL) biases however appear to be more severe...... and persistent in bookmaker markets than in pari-mutuel markets; the latter sometimes exhibit no bias or a reverse FL bias. Our results help understand these differences: the odds grid in bookmaker markets leads to a built-in FL bias, whereas that used in pari-mutuel betting pushes these markets toward a reverse...

Paleoclimate records at high latitude in Arctic during the Paleogene

Science.gov (United States)

Salpin, Marie; Schnyder, Johann; Baudin, François; Suan, Guillaume; Labrousse, Loïc; Popescu, Speranta; Suc, Jean-Pierre

2015-04-01

Paleoclimate records at high latitude in Arctic during the Paleogene SALPIN Marie1,2, SCHNYDER Johann1,2, BAUDIN François1,2, SUAN Guillaume3, LABROUSSE Loïc1,2, POPESCU Speranta4, SUC Jean-Pierre1,4 1: Sorbonne Universités, UPMC Univ Paris 06, UMR 7193, Institut des Sciences de la Terre Paris (iSTeP), F 75005, Paris, France 2: CNRS, UMR 7193, Institut des Sciences de la Terre Paris (iSTeP), F 75005 Paris, France 3: UCB Lyon 1, UMR 5276, LGLTPE, 69622 Villeurbanne Cedex, France 4: GEOBIOSTRATDATA.CONSULTING, 385 Route du Mas Rillier 69140 Rillieux la Pape, France The Paleogene is a period of important variations of the Earth climate system either in warming or cooling. The climatic optima of the Paleogene have been recognized both in continental and marine environment. This study focus on high latitudes of the northern hemisphere, in the Arctic Basin. The basin has had an influence on the Cenozoic global climate change according to its polar position. Is there a specific behaviour of the Arctic Basin with respect to global climatic stimuli? Are there possible mechanisms of coupling/decoupling of its dynamics with respect to the global ocean? To answer these questions a unique collection of sedimentary series of Paleogene age interval has been assembled from the Laurentian margin in Northern Yukon (Canada) and from the Siberian margin (New Siberian Islands). Selected continental successions of Paleocene-Eocene age were used to study the response of the Arctic system to known global events, e.g. the climatic optima of the Paleogene (the so-called PETM, ETM2 or the Azolla events). Two sections of Paleocene-Eocene age were sampled near the Mackenzie delta, the so-called Coal Mine (CoMi) and Caribou Hills (CaH) sections. The aim of the study is to precise the climatic fluctuations and to characterise the source rock potential of the basin, eventually linked to the warming events. This study is based on data of multi-proxy analyses: mineralogy on bulk and clay

Irradiación cultural frente a ruptura diplomática. El mesianismo francés ante el cierre de la frontera española, 1946-1948

Directory of Open Access Journals (Sweden)

Isabelle Cabrolier-Lostanlen

2007-08-01

Full Text Available This work is a study of the option chosen by the men in charge of the French cultural network in Spain, during the closing of the Franco-Spanish frontier, in the years 1946-1948. Their intention was to maintain the cultural exchanges policy between both countries. After World War II, France needed to reaffirm her image as a defender of democratic values, this was the context for the French opposition to the Franco regime. It was also seen as an opportunity to recover her messianic role. However, this conception of «France's mission» in relation to Franco's Spain, in fact, generated two opposing positions. In Paris, a strongly held opinion argued that France had to be the leader of international disapproval, and demanded a boycott of the regime. On the other hand, the people who ran the French art and Education centres in Spain tried to prove that the only valid position France could consider was to maintain cultural and intellectual contacts, in order to represent an opportunity for Spanish democrats to broaden their horizons.

The Coast Artillery Journal. Volume 57, Number 3, September 1922

Science.gov (United States)

1922-09-01

hunting knife, to enjoy the thrills of big game hunting, Trails good for pedestrian and horseman alike catacomb these back areas and lead one to the lairs...of powder are referred to, viz, cannon powder " paris fyne" (whichprobably indicates that it was imported from France, or was of French standard

Journal of Chemical Sciences | Indian Academy of Sciences

Indian Academy of Sciences (India)

S Bhattacharya1 A Kirwai1 Aditya N Panda1 2 H-D Meyer3. Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781 039, India; Department of Chemistry, École Normale Supérieure, Paris, 24 rue Lhomond, 75231 Paris CEDEX 05, France; Theoretische Chemie, Universität Heidelberg, ...

[Survey among academic teachers about psychiatric training in France].

Science.gov (United States)

van Effenterre, A; Hanon, C; Llorca, P-M

2014-06-01

Given the results of resident psychiatrists' surveys conducted in France over the past 3 years, it has become essential to also examine the opinion of the academic psychiatrists in charge of psychiatry education. To study the teachers point of view on psychiatric training in France, the weaknesses and strengths of the training, recent improvements and problems, and to compare their opinion with that of the residents. A survey was conducted in April 2012 among 125 academic teachers professors hospital practitioners (PU-PH), in child & adolescent psychiatry and adult psychiatry. An anonymous online questionnaire including seven parts and three open questions was sent to the PU-PH. The questionnaire was answered by 79/125 psychiatric PU-PH (63%). Results show that a majority of PU-PH (78%) were willing to maintain a single training pathway including adult psychiatry and child psychiatry with a single diploma, with the addition of a DESC (specific and additional Diploma) in forensic psychiatry (72%) and old age psychiatry (62%). Almost all respondents suggested the implementation of an assessment of teaching and a formal mentorship program. Some aspects of training included more controversial issues: such as the length of the training, the opening of training to private practice physicians, or the European harmonization. The survey stressed some areas of improvement: such training in psychotherapy and research, access to supervision as well as barriers to improved training including an insufficient number of academic practitioners. Compared with other surveys, it emphasized that in addition to the need of diversifying the theoretical (thematic, interactive media and teaching, teachers, etc.) and the practical aspect (training sites), it is essential according to trainees and PU-PH, to implement an efficient supervision during residency. Copyright © 2013 L’Encéphale, Paris. Published by Elsevier Masson SAS. All rights reserved.

[Comparative study on specific chromatograms and main active components of wild and cultivated rhizomes of Paris polyphylla var. yunnanensis].

Science.gov (United States)

Zan, Ke; Gao, Yu-Ming; Cui, Gan; Liu, Jie; Guo, Li-Nong; Zheng, Jian; Ma, Shuang-Cheng

2017-08-01

The present study is to compare specific chromatograms and main acitive components between wild and cultivated rhizomes of Paris polyphylla var. yunnanensis by HPLC. HPLC analysis was performed on a Waters XSelect HSS T3 C₁₈ clumn (4.6 mm×250 mm, 5 μm), with a mobile phase consisting of acetonitrile (A)-water (B) at a flow rate of 1 mL•min⁻¹ (0-50 min,30%-50%A;50-80 min,50% A,80-85 min,50%-30%A;85-100 min,30% A). The detection wavelength was 203 nm and the column temperature was controlled at 30 ℃, and the injection volume was 10 μL. HPLC specific chromatograms of wild and cultivated rhizomes of P. polyphylla var. yunnanensis were established and nine steroidal saponins were simultaneously determined by the above method. The mean contents of paris saponin Ⅶ, paris saponin H and total average contents of four pennogenyl saponins in Rhizomes of wild samples were significantly higher than those of cultivated ones. However, this result is opposite from the average content of paris saponin Ⅰ and total average contents of five dioscins in the wild and cultivated samples. Because the significant differences occurred for the specific chromatograms and main active components between the wild and cultivated P. polyphylla var. yunnanensis, much more pharmacological and clinical researches are therefore necessary. Copyright© by the Chinese Pharmaceutical Association.

A 3 D regional scale photochemical air quality model application to a 3 day summertime episode over Paris; Un modele photochimique 3D de qualite de l`air a l`echelle regionale. Application a un episode de 3 jours a Paris en ete

Energy Technology Data Exchange (ETDEWEB)

Jaecker-Voirol, A.; Lipphardt, M.; Martin, B.; Quandalle, Ph.; Salles, J. [Institut Francais du Petrole (IFP), 92 - Rueil-Malmaison (France); Carissimo, B.; Dupont, P.M.; Musson-Genon, L.; Riboud, P.M. [Electricite de France (EDF), 78 - Chatou (France). Direction des Etudes et Recherches; Aumont, B.; Bergametti, G.; Bey, I.; Toupanse, G. [Paris-12 Univ., 94 - Creteil (France). Laboratoire interuniversitaire des systemes atmospheriques]|[Paris-7 Univ., 75 (France)

1998-03-01

This paper presents AZUR, a 3D Eulerian photochemical air quality model for the simulation of air pollution in urban and semi-urban areas. The model tracks gas pollutant species emitted into the atmosphere by transportation and industrial sources, it computes the chemical reactions of these species under varying meteorological conditions (photolysis, pressure, temperature, humidity), their transport by wind and their turbulent diffusion as a function of air stability. It has a modular software structure which includes several components dedicated to specific processes: MERCURE, a meso-scale meteorological model to compute the wind field, turbulent diffusion coefficients, and other meteorological parameters; MIEL, an emission inventory model describing the pollutant fluxes from automotive transportation, domestic and industrial activities; MoCA a photochemical gas phase model describing the chemistry of ozone, NO{sub x}, an hydrocarbon compounds; AIRQUAL, a 3D Eulerian model describing the transport by mean wind flux and air turbulent diffusion of species in the atmosphere, associated with a Gear type chemical equation solver. The model has been applied to a 3-day summertime episode over Paris area. Simulation results are compared to ground level concentration measurements performed by the local monitoring network (Airparif). (authors) 22 refs.

Aendringer i blodprofiler under Tour de France 2007

DEFF Research Database (Denmark)

Mørkeberg, Jakob; Belhage, Bo; Damsgaard, Rasmus

2008-01-01

sports federations. MATERIALS AND METHODS: During the Tour de France 2007, 7 riders were randomly tested on 3 different occasions; the day before the prologue, and 12 and 19 days after the prologue. Blood was drawn into 3 mL EDTA covered tubes and kept at 4 degrees Celsius. They were analyzed within 24...

Redhead (Rubiaceae)

African Journals Online (AJOL)

Erah

Thèse de Doctorat 3è cycle, UFR. Biosciences, Université, Cocody-Abidjan,. 2003; p 144. 19. Xavier L. Rôle du foie dans le métabolisme des nutriments en nutrition artificielle. Nutrition clinique et métabolisme, 1999; 13(4):. 225-231. 20. Eastham RD. Abrégé de constantes biologiques. Edition Masson, Paris-France; 1978;.

Assessing the ammonium nitrate formation regime in the Paris megacity and its representation in the CHIMERE model

Directory of Open Access Journals (Sweden)

H. Petetin

2016-08-01

Full Text Available Secondary inorganic compounds represent a major fraction of fine aerosol in the Paris megacity. The thermodynamics behind their formation is now relatively well constrained but, due to sparse direct measurements of their precursors (in particular NH3 and HNO3, uncertainties remain on their concentrations and variability as well as the formation regime of ammonium nitrate (in terms of limited species among NH3 and HNO3 in urban environments such as Paris. This study presents the first urban background measurements of both inorganic aerosol compounds and their gaseous precursors during several months within the city of Paris. Intense agriculture-related NH3 episodes are observed in spring/summer while HNO3 concentrations remain relatively low, even during summer, which leads to a NH3-rich regime in Paris. The local formation of ammonium nitrate within the city appears low, despite high NOx emissions. The data set also allows evaluating the CHIMERE chemistry-transport model (CTM. Interestingly, the rather good results obtained on ammonium nitrates hide significant errors on gaseous precursors (e.g., mean bias of −75 and +195 % for NH3 and HNO3, respectively. This leads to a misrepresentation of the nitrate formation regime through a highly underestimated gas ratio metric (introduced by Ansari and Pandis, 1998 and a much higher sensitivity of nitrate concentrations to ammonia changes. Several uncertainty sources are investigated, pointing out the importance of better assessing both NH3 agricultural emissions and OH concentrations in the future. These results remind us of the caution required when using of CTMs for emission scenario analysis, highlighting the importance of prior diagnostic and dynamic evaluations.

Petrophysical Properties of the Middle Jurassic Carbonates in the PICOREF Sector (South Champagne, Paris Basin, France Propriétés pétrophysiques du Dogger carbonaté dans le Secteur PICOREF (Sud Champagne, bassin de Paris, France

Directory of Open Access Journals (Sweden)

Delmas J.

2010-05-01

Full Text Available This article, carried out as part of the PICOREF Project for the CO2 storage in the aquifers of the Paris Basin, presents an important petrophysical database from the numerous petroleum wells drilled in the PICOREF Sector (south-eastern part of the Paris Basin between 1953 and 2001. These core data concern the three saline carbonated aquifers of the Middle Jurassic: the Oolithe Blanche and the Comblanchien formations, Upper Bathonian age, and the Dalle Nacrée formation, Lower Callovian age, that would be used for the CO2 sequestration. Located at –1230 to –1750 m sub sea in the studied sector, these carbonate reservoirs which cumulative thickness is about 150 m, outcrop in the Burgundy region, at about 80 km south-eastern the Sector where they are exploited in several quarries. The analysis of the 6800 routine measurements (porosity and permeability gathered for this study allowed to improve the knowledge of the petrophysical properties. Special measurements (mercury injection tests allowed to characterize the porous medium. Cet article, réalisé dans le cadre du Projet PICOREF(1 pour le stockage de CO2 dans les aquifères du bassin parisien, présente une importante base de données pétrophysiques issues des nombreux puits pétroliers forés dans le Secteur PICOREF (sud-est du bassin parisien entre 1953 et 2001. Ces données concernent les trois aquifères salins du Dogger carbonaté susceptibles d’être utilisés pour séquestrer du CO2 : l’Oolithe Blanche et le Comblanchien, d’âge Bathonien supérieur, ainsi que la Dalle Nacrée d’âge Callovien inférieur. Recoupés à des altitudes de – 1230 à – 1750 m/mer dans le secteur étudié, ces réservoirs carbonatés, dont l’épaisseur cumulée est de 150 m environ, affleurent en Bourgogne, à 80 km au sud-est du « Secteur », où ils sont exploités dans plusieurs carrières. L’analyse des 6800 mesures classiques (porosité et perméabilité rassemblées ici a permis d�

DNA Methylation as an Epigenetic Factor in the Development and Progression of Polycythemia Vera

Science.gov (United States)

2009-06-01

Pathol Biol ( Paris ). 2001;49:164-166. 2. Spivak JL. Diagnosis of the myeloproliferative disorders: resolving phenotypic mimicry. Semin Hematol...TX, USA; 9 Laboratoire d’Hématologie, Hôpital Saint-Antoine, Paris , France; 10 Department of Hematology, University of Pavia & Fondazione IRCCS...CHU, Brest , France and 15 Laboratoire d’Hématologie, CHU, Nantes, France. Studies of myeloproliferative disorders (MPDs) aiming to evaluate the

The German ''Energiewende''. Evaluation after the Paris-agreement; Die Deutsche Energiewende. Bewertung nach dem Klima-Abkommen von Paris

Energy Technology Data Exchange (ETDEWEB)

Roth, Eike

2016-12-15

The World-Climate-Summit 2016 in Paris agreed to exacerbated goals for climate protection. This paper will scrutinize whether Germany can comply with its Paris-obligations by continuing the ongoing German ''Energiewende''. The result is clear-cut: The German ''Energiewende'' is inadequate. Due to the cap-and-trade system of the EU the ''Energiewende'' can in no way contribute to climate protection.

Multi-year levels and trends of non-methane hydrocarbon concentrations observed in ambient air in France

Science.gov (United States)

Waked, Antoine; Sauvage, Stéphane; Borbon, Agnès; Gauduin, Julie; Pallares, Cyril; Vagnot, Marie-Pierre; Léonardis, Thierry; Locoge, Nadine

2016-09-01

Measurements of 31 non-methane hydrocarbons (NMHCs) were carried out at three urban (Paris, 2003-2014, Strasbourg, 2002-2014 and Lyon, 2007-2014) sites in France over the period of a decade. A trend analysis was applied by means of the Mann-Kendall non-parametric test to annual and seasonal mean concentrations in order to point out changes in specific emission sources and to assess the impact of emission controls and reduction strategies. The trends were compared to those from three rural sites (Peyrusse-Vieille, 2002-2013, Tardière, 2003-2013 and Donon, 1997-2007). The results obtained showed a significant yearly decrease in pollutant concentrations over the study period and for the majority of species in the range of -1 to -7% in accordance with the decrease of NMHC emissions in France (-5 to -9%). Concentrations of long-lived species such as ethane and propane which are recognized as tracers of distant sources and natural gas remained constant. Compounds associated with combustion processes such as acetylene, propene, ethylene and benzene showed a significant decline in the range of -2% to -5% yr-1. These trends are consistent with those recently described at urban and background sites in the northern mid-latitudes and with emission inventories. C7-C9 aromatics such as toluene and xylenes as well as C4-C5 alkanes such as isopentane and isobutane also showed a significant decrease in the range of -3% to -7% yr-1. The decreasing trends in terms of % yr-1 observed at these French urban sites were typically higher for acetylene, ethylene and benzene than those reported for French rural sites of the national observatory of Measurement and Evaluation in Rural areas of trans-boundary Air pollution (MERA). The study also highlighted the difficult choice of a long term sampling site representative of the general trends of pollutant concentrations.

Risk analysis by citizens? Analysis of the first consensus conference held in France

International Nuclear Information System (INIS)

Marris, C.; Joly, P.B.

1998-01-01

Full text of publication follows: the French Parliamentary Office for the evaluation of scientific and technological choices (OPECST) is currently organizing a consensus conference. Following the model developed by the Danish Board of Technology, a panel of 15 French citizens is being asked to evaluate the use of genetically modified organisms in agriculture and food. This Danish model for direct citizen participation in technology assessment has gained growing support in other European countries and even further afield, such as Japan and Australia. This is, however, a novel experience for France, which has very little tradition for participatory technology assessment. The final and public phase of the 'conference citoyenne' will take place in Paris on 20-22 June 1998, therefore it is too early to outline our results in this abstract. Our paper will present an analysis of the impact and role of this conference in the wider public debate in France about agricultural bio-technologies. This will be based on interviews with key actors in this debate (scientists, consumer and environmental organisations, politicians), media reports, and video footage of the entire procedure of the consensus conference. (authors)

Towards Energy Transition. Scientific workshop of 4 and 6 October 2016. Scientific synthesis of the 4 specialized sessions

International Nuclear Information System (INIS)

2016-10-01

University Paris-Saclay and the R and D of EDF Group organized on 4 and 5 October 2016, at EDF Lab Paris-Saclay, a scientific workshop with prospective vision and exchanges with companies: 'The University Paris-Saclay engine of the Energy Transition'. The workshop was preceded by a forum for students on the energy theme. For two days, major scientific topics were discussed in connection with the energy transition, through three types of exchanges between academics, researchers and students of the University Paris-Saclay and experts from the companies involved. The topics of the workshop were: Solar photovoltaic energy, Nuclear energy, Energy efficiency and flexibility, Electric mobility, Energy systems (including storage) and Energy control, interactions between Energy and Human and social sciences and between Energy and Digital. Scientific presentations and round tables involving researchers from the University Paris-Saclay and experts from companies were organised on prospective themes in order to compare the academic vision and the vision and needs of companies. A poster session that represents the research and innovation skills of the University Paris-Saclay, was highlighting the PhD students and young researchers. A forum for students aimed at presenting the training offer of the University Paris-Saclay on the energy theme. It offered facilitated meetings with companies for the training, orientation and professional integration of students. This document summarizes the scientific content of the four sessions: 1 - means and needs of photovoltaic solar energy, 2 - role of nuclear energy in the energy transition, 3 - new levers for industrial energy efficiency, 4 - electric-powered vehicles for what use?

Contribution of ozone to airborne aldehyde formation in Paris homes.

Science.gov (United States)

Rancière, Fanny; Dassonville, Claire; Roda, Célina; Laurent, Anne-Marie; Le Moullec, Yvon; Momas, Isabelle

2011-09-15

Indoor aldehydes may result from ozone-initiated chemistry, mainly documented by experimental studies. As part of an environmental investigation included in the PARIS birth cohort, the aim of this study was to examine ozone contribution to airborne aldehyde formation in Paris homes. Formaldehyde, acetaldehyde and hexaldehyde levels, as well as styrene, nitrogen dioxide and nicotine concentrations, comfort parameters and carbon dioxide levels, were measured twice during the first year of life of the babies. Ambient ozone concentrations were collected from the closest background station of the regional air monitoring network. Traffic-related nitrogen oxide concentrations in front of the dwellings were estimated by an air pollution dispersion model. Home characteristics and families' way of life were described by questionnaires. Stepwise multiple linear regression models were used to link aldehyde levels with ambient ozone concentrations and a few aldehyde precursors involved in oxidation reactions, adjusting for other indoor aldehyde sources, comfort parameters and traffic-related nitrogen oxides. A 4 and 11% increase in formaldehyde and hexaldehyde levels was pointed out when 8-hour ozone concentrations increased by 20 μg/m(3). The influence of potential precursors such as indoor styrene level and frequent use of air fresheners, containing unsaturated volatile organic compounds as terpenes, was also found. Thus, our results suggest that ambient ozone can significantly impact indoor air quality, especially with regard to formaldehyde and hexaldehyde levels. Copyright © 2011 Elsevier B.V. All rights reserved.

Paris-Princeton lectures on mathematical finance 2010

CERN Document Server

Cousin, Areski; Guéant, Olivier; Hobson, David; Jeanblanc, Monique; Lasry, Jean-Michel; Laurent, Jean-Paul; Lions, Pierre-Louis; Tankov, Peter

2011-01-01

The Paris-Princeton Lectures on Mathematical Finance, of which this is the fourth volume, publish cutting-edge research in self-contained, expository articles from outstanding specialists - established or on the rise! The aim is to produce a series of articles that can serve as an introductory reference source for research in the field. The articles are the result of frequent exchanges between the finance and financial mathematics groups in Paris and Princeton. The present volume sets standards with articles by Areski Cousin, Monique Jeanblanc and Jean-Paul Laurent, Stéphane Crépey, Olivier Guéant, Jean-Michel Lasry and Pierre-Louis Lions, David Hobson, and Peter Tankov.

Alkylphenolic compounds and bisphenol A contamination within a heavily urbanized area: case study of Paris.

Science.gov (United States)

Cladière, Mathieu; Gasperi, Johnny; Lorgeoux, Catherine; Bonhomme, Céline; Rocher, Vincent; Tassin, Bruno

2013-05-01

This study evaluates the influence of a heavily urbanized area (Paris Metropolitan area), on receiving water contamination by both bisphenol A (BPA) and alkylphenol ethoxylate (APE) biodegradation product. The study began by investigating concentrations within urban sources. In addition to the more commonly studied wastewater treatment plant effluent, wet weather urban sources (including combined sewer overflows, urban runoff, and total atmospheric fallout) were considered. The initial results highlight a significant contamination of all urban sources (from a few nanograms per liter in atmospheric fallout to several micrograms per liter in the other sources) with clearly distinguishable distribution patterns. Secondly, concentration changes along the Seine River from upstream of the Paris Metropolitan area to downstream were investigated. While the concentrations of BPA and nonylphenoxy acetic acid (NP₁EC) increase substantially due to urban sources, the 4-nonylphenol concentrations remain homogeneous along the Seine. These results suggest a broad dissemination of 4-nonylphenol at the scale of the Seine River basin. Moreover, the relationship between pollutant concentrations and Seine River flow was assessed both upstream and downstream of the Paris conurbation. Consequently, a sharp decrease in dissolved NP1EC concentrations relative to Seine River flow underscores the influence of single-point urban pollution on Seine River contamination. Conversely, dissolved 4-nonylphenol concentrations serve to reinforce the hypothesis of its widespread presence at the Seine River basin scale.

Energy and Global Climate Change: The Road from Paris to Denver

Energy Technology Data Exchange (ETDEWEB)

Logan, Jeffrey

2016-10-27

This presentation provides an overview of the National Renewable Energy Laboratory; a snapshot of U.S. power sector transformation; a brief history of climate negotiations; an overview of the Paris Agreement; and what the Paris Agreement means for Colorado and beyond.

Three centuries of heavy metal pollution in Paris (France) recorded by urban speleothems.

Science.gov (United States)

Pons-Branchu, Edwige; Ayrault, Sophie; Roy-Barman, Matthieu; Bordier, Louise; Borst, Wolfgang; Branchu, Philippe; Douville, Eric; Dumont, Emmanuel

2015-06-15

The first record of urban speleothems used to reconstruct the history of heavy metal pollution of shallow groundwaters is presented. Two speleothems grew during the last 300 years in an underground aqueduct in the north-eastern part of Paris. They display high Pb, Mn V, Cu, Cd and Al concentrations since 1900 due to the urbanization of the site which triggered anthropogenic contamination of the water feeding the speleothems. Surprisingly, these heavy metal concentrations are also high in the oldest part. This early pollution could come from the use of Parisian waste as fertilizers in the orchards and vineyards cultivated above the aqueduct before urbanization. Lead isotopes were measured in these carbonates as well as in lead artifacts from the 17th-18th centuries ((206)Pb/(207)Pb=1.180+/-0.003). The mean (206)Pb/(207)Pb ratio, for one of the speleothems is 1.181+/-0.003 unvarying with time. These lead signatures are close to those of coal and old lead from northern European mines, lower than the natural background signature. It confirms that the high metal concentrations found come from anthropogenic pollution. Conversely, the lead isotopic composition of the second speleothem presents two temporal trends: for the oldest levels, the mean value (1.183+/-0.003) is similar to the first speleothem. For the youngest part, a lower value (1.172+/-0.005) is recorded, evidencing the contribution of a new lead source at the beginning of the industrial revolution. Pb isotopes were also measured in recent samples from a nearby superficial site. The first sample is a recent (AD 1975+/-15 years) deposit ((206)Pb/(207)Pb=1.148+/-0.003), and the second, a thin subactual layer ((206)Pb/(207)Pb=1.181+/-0.002). These data are compatible with the adding of anthropogenic sources (leaded gasoline and industrial lead from Rio Tinto ore). Copyright © 2015 Elsevier B.V. All rights reserved.

Evaluating the Effectiveness of France's Indoor Smoke-Free Law 1 Year and 5 Years after Implementation: Findings from the ITC France Survey.

Science.gov (United States)

Fong, Geoffrey T; Craig, Lorraine V; Guignard, Romain; Nagelhout, Gera E; Tait, Megan K; Driezen, Pete; Kennedy, Ryan David; Boudreau, Christian; Wilquin, Jean-Louis; Deutsch, Antoine; Beck, François

2013-01-01

France implemented a comprehensive smoke-free law in two phases: Phase 1 (February 2007) banned smoking in workplaces, shopping centres, airports, train stations, hospitals, and schools; Phase 2 (January 2008) banned smoking in hospitality venues (bars, restaurants, hotels, casinos, nightclubs). This paper evaluates France's smoke-free law based on the International Tobacco Control Policy Evaluation Project in France (the ITC France Project), which conducted a cohort survey of approximately 1,500 smokers and 500 non-smokers before the implementation of the laws (Wave 1) and two waves after the implementation (Waves 2 and 3). Results show that the smoke-free law led to a very significant and near-total elimination of observed smoking in key venues such as bars (from 94-97% to 4%) and restaurants (from 60-71% to 2-3%) at Wave 2, which was sustained four years later (6-8% in bars; 1-2% in restaurants). The reduction in self-reported smoking by smoking respondents was nearly identical to the effects shown in observed smoking. Observed smoking in workplaces declined significantly after the law (from 41-48% to 18-20%), which continued to decline at Wave 3 (to 14-15%). Support for the smoke-free laws increased significantly after their implementation and continued to increase at Wave 3 (plaws, smoking in the home did not increase after the law was implemented and prevalence of smoke-free homes among smokers increased from 23.2% before the law to 37.2% 5 years after the law.

Media use and insomnia after terror attacks in France.

Science.gov (United States)

Goodwin, Robin; Lemola, Sakari; Ben-Ezra, Menachem

2018-03-01

Direct exposure to traumatic events often precipitates sleep disorders. Sleep disturbance has also been observed amongst those indirectly exposed to trauma, via mass media. However, previous work has focused on traditional media use, rather than contemporary social media. We tested associations between both traditional and social media consumption and insomnia symptoms following 2015 terror attacks in Paris France, controlling for location and post-traumatic symptomology. 1878 respondents, selected to represent the national French population, completed an internet survey a month after the Bataclan attacks (response rate 72%). Respondents indicated different media use, post-traumatic stress and insomnia. Controlling for demographics, location and PTSD, insomnia was associated with both traditional (β 0.10, P = .001) and social media use (β 0.12, P = .001). Associations between social media and insomnia were independent of traditional media use. Interventions targeted at social media may be particularly important following mass trauma. Copyright © 2017 Elsevier Ltd. All rights reserved.

Paris 2000 researches and men; Paris 2000 des recherches et des hommes

Energy Technology Data Exchange (ETDEWEB)

NONE

2000-07-01

The IWA and ISWA congresses organized in Paris in july showed the latest research developments in the field of water and wastes management. The water sector is more mature than the waste sector but for both a closer association of the public and private is increasing. A summary of the presentations in successively the water and the wastes management is proposed bringing an analysis of the international situation and regulations. (A.L.B.)

Accuracy of the ankle-brachial index using the SCVL®, an arm and ankle automated device with synchronized cuffs, in a population with increased cardiovascular risk

Directory of Open Access Journals (Sweden)

Rosenbaum D

2012-04-01

Full Text Available David Rosenbaum1,2, Sandra Rodriguez-Carranza1,3, Patrick Laroche4, Eric Bruckert1,2, Philippe Giral1,2, Xavier Girerd1,21Unité de Prévention Cardiovasculaire, Service d'Endocrinologie-Métabolisme, Assistance Publique/Hôpitaux de Paris, Groupe Hospitalier Pitié-Salpêtrière – Université Pierre et Marie Curie, 2Dyslipoproteinemia and Atherosclerosis Research Unit, National Institute for Health and Medical Research (INSERM and Pierre et Marie Curie University (UPMC – Paris VI, Paris, France; 3Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán Departamento de Endocrinología y Metabolismo, Delegación Tlalpan, México Distrito Federal; 4STACTIS, Paris, FranceObjective: To evaluate the accuracy of the ankle brachial index (ABI measured with the SCVL® (“screening cardiovascular lab”; GenNov, Paris, France, an automated device with synchronized arm and ankle cuffs with an automatic ABI calculation.Methods: Patients were consecutively included in a cardiovascular prevention unit if they presented with at least two cardiovascular risk factors. ABI measurements were made using the SCVL, following a synchronized assessment of brachial and ankle systolic pressure. These values were compared to the ABI obtained with the usual Doppler-assisted method.Results: We included 157 patients. Mean age was 59.1 years, 56.8% had hypertension, 22.3% had diabetes mellitus, and 17.6% were current smokers. An abnormal ABI was observed in 17.2% with the SCVL and in 16.2% with the Doppler. The prevalence rates of an abnormal ABI by patient measured with each device, ie, 15.7% (confidence interval [CI] 0.95: [11.8; 20.4] or 14.3% (CI 0.95: [10.7; 18.9], did not differ. The coefficient of variation of Doppler and SCVL measures was 15.8% and 15.1%, respectively. The regression line between the two measurement methods was statistically significant. The value-to-value comparison also shows a difference of mean equal to 0.010 (CI 0.95: [–0

XXII EAACI congress, Paris (France)

African Journals Online (AJOL)

Ehab

2017-04-13

Apr 13, 2017 ... Please visit our website for details of ESPAI 2017 Congress and the WATS! I also encourage you all to hurry and register to participate in the World Allergy Organization Symposium. (Hot Topics in Allergy: Pediatric and Regulatory Aspects) that will be held in Rome/Vatican City, on April 27-29,. 2017. There.

Assessment of seasonal and year-to-year surface salinity signals retrieved from SMOS and Aquarius missions in the Bay of Bengal

Digital Repository Service at National Institute of Oceanography (India)

Akhil, V.P.; Lengaigne, M.; Durand, F.; Vialard, J.; Chaitanya, A.V.S.; Keerthi, M.G.; Gopalakrishna, V.V.; Boutin, J.; de Boyer, M.C.

, Sorbonne Universités (UPMC, Univ Paris 06)-CNRS-IRD-MNHN, Paris, France; dNIO, Goa, India; eLOS, IFREMER, Plouzané, France ABSTRACT The Bay of Bengal (BoB) exhibits a wide range of sea surface salinity (SSS), with very fresh water induced by heavy monsoonal...

Porphyry of Russian Empires in Paris

Science.gov (United States)

Bulakh, Andrey

2014-05-01

Porphyry of Russian Empires in Paris A. G. Bulakh (St Petersburg State University, Russia) So called "Schokhan porphyry" from Lake Onega, Russia, belongs surely to stones of World cultural heritage. One can see this "porphyry" at facades of a lovely palace of Pavel I and in pedestal of the monument after Nicolas I in St Petersburg. There are many other cases of using this stone in Russia. In Paris, sarcophagus of Napoleon I Bonaparte is constructed of blocks of this stone. Really, it is Proterozoic quartzite. Geology situation, petrography and mineralogical characteristic will be reported too. Comparison with antique porphyre from the Egyptian Province of the Roma Empire is given. References: 1) A.G.Bulakh, N.B.Abakumova, J.V.Romanovsky. St Petersburg: a History in Stone. 2010. Print House of St Petersburg State University. 173 p.

Meeting of October 20, 2005 of the working group about the division by 4 of greenhouse gas emissions of France at the 2050 prospects, named 'factor 4'

International Nuclear Information System (INIS)

2005-01-01

This document gathers 4 presentations given at this meeting of the 'Factor 4' working group: the first presentation (C. Parent) presents the 2050 prospective of transports demand and the transport offer variables (world context, specific European actions, French context and taxation, impact of the different scenarios on road traffic, energy consumption and CO 2 emissions). The second presentation (P. Aussourd) treats of the energy approaches of the transport prospective for 2050 (definition of 4 scenarios, global consequences in terms of fiscal income, energy consumption and CO 2 emissions, lessons gained, possibility of an incremental scenario with chargeable hybrid vehicles, use of short crises for a long-term action in the change of life styles). The third presentation (R. Lavergne) deals with the energy prospective for the energy demand in France at the 2050 prospects (definition of a reference scenario, sectoral analysis, main hypotheses, critical points). The last presentation (H. Prevot) explains how it is possible for France to divide by 2 or 3 the CO 2 emissions with keeping the same energy consumption as for the year 2000 (optimum combination of energy sources, use of biomass and solar space heating, power generation by nuclear energy, coal with CO 2 sequestration and wind energy, evolution of fuel prices, role of the public action and of the government, convincing the decision makers). (J.S.)

Active Visual SLAM with Exploration for Autonomous Underwater Navigation

Science.gov (United States)

2012-01-01

tourism. Reconstruction of Notre Dame de Paris (Snavely et al., 2006). (c) Web-scale landmark recognition engine (Zheng et al., 2009). eters for an...structures, such as Notre Dame Cathedral in Paris and the Great Wall of China (Figure 1.3(b)), using photographs compiled from the Internet. Given the...Exhibition, vol. 3, pp. 378–383, Brest , France. Brown, M., and D. G. Lowe (2005), Unsupervised 3D object recognition and reconstruction in unordered

Air-quality in the mid-21st century for the city of Paris under two climate scenarios; from regional to local scale

OpenAIRE

K. Markakis; M. Valari; A. Colette; O. Sanchez; O. Perrussel; C. Honore; R. Vautard; Z. Klimont; S. Rao

2014-01-01

Ozone and PM2.5 concentrations over the city of Paris are modeled with the CHIMERE air-quality model at 4 km × 4 km horizontal resolution for two future emission scenarios. High-resolution (1 km × 1 km) emission projection until 2020 for the greater Paris region is developed by local experts (AIRPARIF) and is further extended to year 2050 based on regional scale emission projections developed by the Global Energy Assessment. Model evaluation is performed bas...

A safe energy supplying for France

International Nuclear Information System (INIS)

Toffin-Payne, J.

2001-01-01

Contrarily to other European nations like United-kingdom, Germany or Norway, France has no important fossil energy resources. The 2 major oil crisis (in 1973 and 1979) made public opinion abruptly aware of the urgent necessity for the diversification of energy supplying. Today the French production of electricity rests on nuclear energy, fossil energy and renewable energies (hydroelectricity). France is the first European country for nuclear energy (88 millions tons of oil equivalent in 1999) and for renewable energy (29 millions toe). The energy independence rate has sharply increased in 20 years from 26% in 1973 it reaches now 49%. France has developed an important capacity of fossil fuels storage about 10.5 milliards m 3 , it means that France can face a 30% decrease in its energy imports for a year without reducing its industrial output. Because of their energy choices Switzerland and France are the European countries the least sensible to price fluctuations of oil and gas. The doubling of oil price has implied a 0.32 francs rise of kWh cost in France and a 1.8 francs rise elsewhere in Europe. (A.C.)

Use of experimental plots for assessing Chernobyl-derived fallout of 137CS in France

International Nuclear Information System (INIS)

Bonte, Ph.; Sogon, S.; Bourgeois, S.; Terce, M.; Morel, Ch.

2004-01-01

Caesium-137 ( 137 Cs) is widely used for the determination of soil erosion and sedimentation rates. However, in Europe, if the additional inputs of 137 Cs fallout associated with the Chernobyl accident have given a supplementary mark to know the chronological history of buried sediments in rivers or wetlands, they have considerably complicated the interpretation of 137 Cs inventories used for estimating soil redistribution on slopes. In fact, determination of Chernobyl-derived fallout 137 Cs is problematic because very few sites have been correctly sampled at the moment of the accident. During the ten years after, it was possible to estimate the fallout measuring the 134 Cs activity for estimating 137 Cs ( 137 Cs / 134 Cs 2.0 at the time of the accident). But these measurements are extremely rare, whereas it should be the more accurate method to resolve this question. The more used solution is to use model based on atmospheric circulation and rain precipitation, the main part of fallout been due to atmospheric washing by the rain. Other solution is to compare 137 Cs specific activity of soil samples collected after the accident and older samples. Then, we choose a set of soil samples collected on several experimental plots at different places in France, and sampled before and after the Chernobyl accident, to determine the part of contamination linked to this 137 Cs fallout event with a simple comparison of their 137 Cs specific activity. In fact, national French institutes working on agronomy maintain experimental plots, with varied surface area (1 m 2 10 m 2 or larger), for monitoring of soil physics and chemistry evolution. Nine sites were studied: two of them close to Paris, one 100 km east of Paris, 3 in Loire basin and 3 in south west, in the Pyrenees Atlantic. These measurements confirm the influence of the Chernobyl radioactive plume over the Paris Basin concerning the 137 Cs fallout. The 137 Cs specific activity is, on average, 25% (from 18 to 35% at

How to estimate exposure when studying the temperature-mortality relationship? A case study of the Paris area.

Science.gov (United States)

Schaeffer, Laura; de Crouy-Chanel, Perrine; Wagner, Vérène; Desplat, Julien; Pascal, Mathilde

2016-01-01

Time series studies assessing the effect of temperature on mortality generally use temperatures measured by a single weather station. In the Paris region, there is a substantial measurement network, and a variety of exposure indicators created from multiple stations can be tested. The aim of this study is to test the influence of exposure indicators on the temperature-mortality relationship in the Paris region. The relationship between temperature and non-accidental mortality was assessed based on a time series analysis using Poisson regression and a generalised additive model. Twenty-five stations in Paris and its three neighbouring departments were used to create four exposure indicators. These indicators were (1) the temperature recorded by one reference station, (2) a simple average of the temperatures of all stations, (3) an average weighted on the departmental population and (4) a classification of the stations based on land use and an average weighted on the population in each class. The relative risks and the Akaike criteria were similar for all the exposure indicators. The estimated temperature-mortality relationship therefore did not appear to be significantly affected by the indicator used, regardless of study zone (departments or region) or age group. The increase in temperatures from the 90(th) to the 99(th) percentile of the temperature distribution led to a significant increase in mortality over 75 years (RR = 1.10 [95% CI, 1.07; 1.14]). Conversely, the decrease in temperature between the 10(th) and 1(st) percentile had a significant effect on the mortality under 75 years (RR = 1.04 [95% CI, 1.01; 1.06]). In the Paris area, there is no added value in taking multiple climatic stations into account when estimating exposure in time series studies. Methods to better represent the subtle temperature variations in densely populated areas in epidemiological studies are needed.

[Venereal granuloma (donovaniasis) in France].

Science.gov (United States)

Duperrat, B; Labouche, F

1975-01-01

The study of six cases of MacLeod-Donovan chancre, 2 in Paris, 4 in Brest, in young men coming from the West Indies, showed after 15 days incubation, a balano-preputial lesion consisting of an oval-shaped granuloma, 1 to 4 cm diameter, raised, indurated, ulcerated, reddish-yellow, spontaneously painful, bleeding easily, accompanied in 50 p. 100 of cases by inguinal adenitis, due to secondary infection. Swabs, which should be repeated, showed Donovan bodies within numerous histiocytes. The inactivity of penicillin may be contrasted with the rapidly favourable effect of streptomycin, chloramphenicol or aureomycin.

Comparison of the chemical quality of rainwater harvested from roof ...

African Journals Online (AJOL)

2018-04-02

Apr 2, 2018 ... 4, place Jussieu 75252 Paris Cedex 05, France ... Keywords: rainwater harvesting, roof-harvested rainwater, pollution, human health, food security, ... Received 18 December 2015; accepted in revised form 26 March 2018.

Where are the radioactive wastes in France? Brochure no 3

International Nuclear Information System (INIS)

2004-01-01

This document is one of the 6 regional brochures which make the geographical inventory of radioactive wastes in France. For each region, a table lists the recorded sites and a regional map localizes those having a detailed descriptive file. These files mention the most important waste owners (medical, research, nuclear and military industries), the type of waste and the type of management. The polluted sites are also mentioned, even if they are already decontaminated. The volume no 3 concerns the Nord-Pas-de-Calais, Picardie, Champagne-Ardenne, Bourgogne, Alsace, Lorraine, Franche-Comte regions. (J.S.)

The C'JAAD: a French team for early intervention in psychosis in Paris.

Science.gov (United States)

Oppetit, Alice; Bourgin, Julie; Martinez, Gilles; Kazes, Mathilde; Mam-Lam-Fook, Célia; Gaillard, Raphael; Olié, Jean-Pierre; Krebs, Marie-Odile

2018-04-01

The aim is to describe a centre operating in Paris that pioneers the early intervention for young people at the onset and at high risk of psychosis in France. Comprehensive descriptive analysis of different clinical and service measures is used in describing the implementation of the C'JAAD (Evaluation Centre for Young Adults and Adolescents) using data from an ongoing prospective non-interventional research programme. Over a 2-year period, 151 patients were referred to the C'JAAD and included in the ICAAR research programme. After evaluation by the Comprehensive Assessment of the At-Risk Mental States Scale, 53.7% were identified at risk of developing a psychosis, 20.6% presented a full-blown psychosis and 25.7% were considered not at risk of developing a psychosis. A total of 84% of the at-risk subjects suffered from a psychiatric co-morbidity, of which anxiodepressive symptoms being the most frequent (39%). The global functioning of these at-risk subjects was seriously impaired (average Social and Occupational Functioning Assessment Scale score = 48.9). More than one third of the patients was self-referred (33.8%), 22.5% were addressed by a psychiatrist whereas 10.6% were referred by a general practitioner. In this paper, we report for the first time the activities of the C'JAAD, the pioneer unit in France for early detection and treatment of young adults with early psychosis. These observations indicate that such early intervention centre is a feasible and sustainable extension of traditional care for people with mental disorders in this country and offers promising perspective for the development of further centres. © 2016 John Wiley & Sons Australia, Ltd.

USA Withdrawal from Paris Agreement – What Next?

OpenAIRE

Sergey Chestnoy; Dinara Gershinkova

2017-01-01

In June 2017, President Trump announced the USA’s withdrawal from the Paris Climate Accord, which had been ratified for less than a year, thanks in large part to the USA. That drastic shift followed the change in residency at the White House. Withdrawing from the Paris Accord presents an interesting topic for analysis. There’s the practical side of the withdrawal procedure as set out in Article 28 of the agreement, not to mention the consequences of US non-participation in address...

Relations du voyage du prince Honoré II de Monaco à la cour de France (octobre 1646-mai 1647)

OpenAIRE

Venasque-Ferriol, Charles de; Bressan, Hyacinthe de

2014-01-01

Un protectorat devenu envahissant et le déclin des Habsbourg conduisent les Grimaldi de Monaco à quitter la domination espagnole et à se placer, en 1641, sous la protection du roi de France. L’application de l’accord appelle quatre séjours à la cour en dix ans. Le voyage de 1646-1647, en pleine Fronde, est surtout justifié par les doléances par rapport aux engagements royaux. La pérégrination de la petite suite princière jusqu’à Paris est aussi l’occasion d’un pèlerinage dans les fiefs frança...

[3D printing in health care facilities: What legislation in France?].

Science.gov (United States)

Montmartin, M; Meyer, C; Euvrard, E; Pazart, L; Weber, E; Benassarou, M

2015-11-01

Health care facilities more and more use 3D printing, including making their own medical devices (MDs). However, production and marketing of MDs are regulated. The goal of our work was to clarify what is the current French regulation that should be applied concerning the production of custom-made MDs produced by 3D printing in a health care facility. MDs consist of all devices used for diagnosis, prevention, or treatment of diseases in patients. Prototypes and anatomic models are not considered as MDs and no specific laws apply to them. Cutting guides, splints, osteosynthesis plates or prosthesis are MDs. In order to become a MD manufacturer in France, a health care facility has to follow the requirements of the 93/42/CEE directive. In addition, custom-made 3D-printed MDs must follow the annex VIII of the directive. This needs the writing of a declaration of conformity and the respect of the essential requirements (proving that a MD is secure and conform to what is expected), the procedure has to be qualified, a risk analysis and a control of the biocompatibility of the material have to be fulfilled. The documents proving that these rules have been respected have to be available. Becoming a regulatory manufacturer of MD in France is possible for a health care facility but the specifications have to be respected. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

Reliability data banks at Electricite de France (EDF)

International Nuclear Information System (INIS)

Procaccia, H.

1991-01-01

When Electricite de France opted for a policy of rapid development of PWR nuclear power plants only foreign data was available on plant operation to start a computerized data bank. Since 1978 however, a specific French data bank has been built up. The collected data are recorded on a central computer near Paris. This article describes the component reliability bank. First a history of the banks' development, which has taken place in four steps, is described. Then the data bank itself, known as SRDF, is explained. It allows computation of the component failure rates in operation, on standby or on demand, their development with time, the corresponding unavailability and repair time, the modes and causes of failure, the affected subcomponents and the consequences of the failure on the plant. To achieve this SRDF has three subfiles, the identification file, the operating file and the failure file. The components monitored are listed. Data processing, and data retrieval are explained and some examples given of studies performed using SRDF. (UK)

Polyp Morphology: An Interobserver Evaluation for the Paris Classification Among International Experts

NARCIS (Netherlands)

van Doorn, Sascha C.; Hazewinkel, Y.; East, James E.; van Leerdam, Monique E.; Rastogi, Amit; Pellisé, Maria; Sanduleanu-Dascalescu, Silvia; Bastiaansen, Barbara A. J.; Fockens, Paul; Dekker, Evelien

2015-01-01

OBJECTIVES: The Paris classification is an international classification system for describing polyp morphology. Thus far, the validity and reproducibility of this classification have not been assessed. We aimed to determine the interobserver agreement for the Paris classification among seven Western

Energy options in France

International Nuclear Information System (INIS)

Carle, R.

1980-01-01

The rapid rise of oil price and the future shortage of oil are the problems, to which those in charge of energy must face. The method of maintaining and increasing energy consumption without destroying financial balance must be found. As the common points in Japan and France, domestic energy resources are scarce, coal reserves are small and the cost is high, the room for expanding water power generation hardly remains, and the atomic energy projects of large scale seem to be the only solution, but actually, they encountered many difficulties. In France, Energy Conservation Agency was established in 1974. The energy consumption per man was 4500 kWh in 1979, and it is not high level, accordingly it is difficult to reduce the present consumption further. The growth of electricity consumption in 1979 slowed down remarkably. The present crisis is oil crisis instead of energy crisis. Therefore electric power is the most suitable medium to get rid of the bondage of oil. The breakdown of heat production is as follows: coal 41%, oil 32%, gas 4%, and uranium 23%. Since 1976, 15 power plants of 3.5 million kW were converted to coal burning, but more staffs are required for the operation and maintenance. Water power generation is valuable to supplement nuclear power generation which lacks flexibility. As the nucleus of energy projects in France, PWR development project is in progress. Six 900 MW PWR plants are in operation. (Kako, I.)

The Biosphere Under Potential Paris Outcomes

Science.gov (United States)

Ostberg, Sebastian; Boysen, Lena R.; Schaphoff, Sibyll; Lucht, Wolfgang; Gerten, Dieter

2018-01-01

Rapid economic and population growth over the last centuries have started to push the Earth out of its Holocene state into the Anthropocene. In this new era, ecosystems across the globe face mounting dual pressure from human land use change (LUC) and climate change (CC). With the Paris Agreement, the international community has committed to holding global warming below 2°C above preindustrial levels, yet current pledges by countries to reduce greenhouse gas emissions appear insufficient to achieve that goal. At the same time, the sustainable development goals strive to reduce inequalities between countries and provide sufficient food, feed, and clean energy to a growing world population likely to reach more than 9 billion by 2050. Here, we present a macro-scale analysis of the projected impacts of both CC and LUC on the terrestrial biosphere over the 21st century using the Representative Concentration Pathways (RCPs) to illustrate possible trajectories following the Paris Agreement. We find that CC may cause major impacts in landscapes covering between 16% and 65% of the global ice-free land surface by the end of the century, depending on the success or failure of achieving the Paris goal. Accounting for LUC impacts in addition, this number increases to 38%-80%. Thus, CC will likely replace LUC as the major driver of ecosystem change unless global warming can be limited to well below 2°C. We also find a substantial risk that impacts of agricultural expansion may offset some of the benefits of ambitious climate protection for ecosystems.

Housing and the construction of the city: the Paris Habitat Experience

Directory of Open Access Journals (Sweden)

Javier Arpa

2015-12-01

Full Text Available In Paris, the history and the evolution of social housing provision merge with those of a centennial institution. Created in 1914, the Office Public d’Habitations à Bon Marché, currently called Paris Habitat, manages more than 1,200 operations, 120,000 housing units inhabited by 200,000 residents. This article reviews an investigation to this exceptional heritage commissioned by the Pavillon de l'Arsenal in Paris, which resulted in the exhibition and catalogue Paris Habitat: Cent ans de ville, cent ans de vie, presented by the institution in 2015.The investigation, exhibition and publication were organized around the analysis of ten fragments of reality that, rather than matching administrative divisions or urban planning projects, span municipalities, districts and infrastructures. From low-cost to large-scale housing, from concerns with hygiene to ecology issues, each one of the building ensembles analyzed bears witness to the will to change society through housing. Written by the project’s main curator and catalogue editor, this review details the process through which essential questions formulated early on – What is the city we want like? How is it built? – were answered to: selecting from the wealth of material produced by Paris Habitat over one hundred years of activity, the team exposed their political stance on urban strategies at large. Importantly, Paris Habitat’s ‘actions’ substantiated the team’s belief that our knowledge of this long, continuous urban experiment can contribute to improve the metropolises of today and strengthen its ability to answer contemporary concerns: the transformation of offices into housing, new residents’ participation formulas, new building and conception processes, which are key elements in the making of cities that need to be dense, diverse, intense, fertile and agile.

Un canoéiste du CERN vice-champion de France V3

CERN Multimedia

Canoe-Kayak Club

2016-01-01

Le monde du canoë-kayak slalom à rendez-vous depuis le 23 juillet à Bourg Saint Maurice pour une semaine de compétition pour disputer les championnats de France. Les  hostilités ont commencé par les catégories masters qui comptent d’anciens membres de l’équipe de France et des grands noms qui ont fait la gloire du canoë kayak, comme le duo Adisson-Forgues  champion olympique de canoë biplace en 1996, Philippe Quemerais double champion du monde de canoë biplace en 1999, 2002 et 5ème des jeux d’Athènes et des participants au passé plus modeste comme Olivier Barrière qui représentait le Canoë Kayak CERN en canoë monoplace ‘’C1’’ et en kayak ‘’K1’’ dans la catégorie homme V3 (45-50ans). A l&am...

Observing System Evaluations Using GODAE Systems

Science.gov (United States)

2009-09-01

Climate (OOPC)-GODAE meeting on OSSEs and OSEs was held at UNESCO/IOC in Paris , France, in November 2007 (www.godae.org/ OSSE-OSE.html). It was the...Institut francais de recherche pour Sexploitation de la mer, Centre de Brest , Plouzane, France. Matthew J. Martin is Ocean Data Assimilation Scientist...participants of the OOPC-GODAE meeting on OSSEs and OSEs, UNESCO/ IOC, Paris , France, in November 2007 are gratefully acknowledged for their

Paris: Beyond the Climate Dead End through Pledge and Review?

Directory of Open Access Journals (Sweden)

Robert O. Keohane

2016-09-01

Full Text Available The Paris Climate Agreement of December 2015 marks a decisive break from the unsuccessful Kyoto regime. Instead of targets and timetables, it established a Pledge and Review system, under which states will offer Nationally Determined Contributions (INDCs to reducing emissions that cause climate change. But this successful negotiation outcome was achieved at the price of vagueness of obligations and substantial discretion for governments. Many governments will be tempted to use the vagueness of the Paris Agreement, and the discretion that it permits, to limit the scope or intensity of their proposed actions. Whether Pledge and Review under the Paris Agreement will lead to effective action against climate change will therefore depend on the inclination both of OECD countries and newly industrializing countries to take costly actions, which for the OECD countries will include financial transfers to their poorer partners. Domestic politics will be crucial in determining the attitudes of both sets of countries to pay such costs. The actual impact of the Paris Agreement will depend on whether it can be used by domestic groups favoring climate action as a point of leverage in domestic politics—that is, in a “two-level game” simultaneously involving both international and domestic politics.

The true artist helps the world by revealing mystic truths: recent European exhibitions on art and spirituality

NARCIS (Netherlands)

Bauduin, T.M.

2010-01-01

The article reviews several exhibitions, including "Traces du Sacré" at the Centre Pompidou in Paris, France, "The Message: Kunst und Okkultismus (Art and the Occult" at the Bochum Kunstmuseum in Germany and "Hilma af Klint: une modernité révelée" at the Swedish cultural center in Paris, France..

France

International Nuclear Information System (INIS)

Hourcade, J.C.

1990-01-01

The French energy system, like that of most energy-importing nations, was profoundly transformed by the first oil shock. But France was more vulnerable than any other industrialized country besides Japan to oil supply disruption: in 1973, the nation imported 77 percent of total primary energy requirements of 7.6 EJ, and 98 percent of its petroleum. Two imperatives have since formed the 'French response' to the threat of external energy supply disruptions: augmentation of the rate of energy self-sufficiency, and minimization of major macroeconomic dislocations. These two objectives displaced a high priority in France in the early 1970s - protection of the natural environment. Because France has embraced nuclear power, it is often viewed by its European neighbors as having feeble ecological sensibility. At that time, France had a rather advanced policy in this field: sulfur emissions laws were enacted in 1967 and a Ministry of Environment was created in January 1971. Now that environmental concerns have re-emerged as an important force, France finds itself with a plausible greenhouse response in a mix of policies - without environmental protection having been the objective envisioned

Patient journey in decompensated heart failure: An analysis in departments of cardiology and geriatrics in the Greater Paris University Hospitals.

Science.gov (United States)

Laveau, Florent; Hammoudi, Nadjib; Berthelot, Emmanuelle; Belmin, Joël; Assayag, Patrick; Cohen, Ariel; Damy, Thibaud; Duboc, Denis; Dubourg, Olivier; Hagege, Albert; Hanon, Olivier; Isnard, Richard; Jondeau, Guillaume; Labouree, Florian; Logeart, Damien; Mansencal, Nicolas; Meune, Christophe; Pautas, Eric; Wolmark, Yves; Komajda, Michel

2017-01-01

Hospitalization for worsening/acute heart failure is increasing in France, and limited data are available on referral/discharge modalities. To evaluate patients' journeys before and after hospitalization for this condition. On 1 day per week, between October 2014 and February 2015, this observational study enrolled 260 consecutive patients with acute/worsening heart failure in all 10 departments of cardiology and four of the departments of geriatrics in the Greater Paris University Hospitals. First medical contact was an emergency unit in 45% of cases, a general practitioner in 16% of cases, an emergency medical ambulance in 13% of cases and a cardiologist in 13% of cases; 78% of patients were admitted directly after first medical contact. In-hospital stay was 13.2±11.3 days; intensive care unit stay (38% of the population) was 6.4±5 days. In-hospital mortality was 2.7%. Overall, 63% of patients were discharged home, whereas 21% were transferred to rehabilitation units. A post-discharge outpatient visit was made by only 72% of patients within 3 months (after a mean of 45±28 days). Only 53% of outpatient appointments were with a cardiologist. Emergency departments, ambulances and general practitioners are the main points of entry before hospitalization for acute/worsening heart failure. Home discharge occurs in two of three cases. Time to first patient post-discharge visit is delayed. Therefore, actions to improve the patient journey should target primary care physicians and emergency structures, and efforts should be made to reduce the time to the first visit after discharge. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

Polyp morphology: an interobserver evaluation for the Paris classification among international experts.

Science.gov (United States)

van Doorn, Sascha C; Hazewinkel, Y; East, James E; van Leerdam, Monique E; Rastogi, Amit; Pellisé, Maria; Sanduleanu-Dascalescu, Silvia; Bastiaansen, Barbara A J; Fockens, Paul; Dekker, Evelien

2015-01-01

The Paris classification is an international classification system for describing polyp morphology. Thus far, the validity and reproducibility of this classification have not been assessed. We aimed to determine the interobserver agreement for the Paris classification among seven Western expert endoscopists. A total of 85 short endoscopic video clips depicting polyps were created and assessed by seven expert endoscopists according to the Paris classification. After a digital training module, the same 85 polyps were assessed again. We calculated the interobserver agreement with a Fleiss kappa and as the proportion of pairwise agreement. The interobserver agreement of the Paris classification among seven experts was moderate with a Fleiss kappa of 0.42 and a mean pairwise agreement of 67%. The proportion of lesions assessed as "flat" by the experts ranged between 13 and 40% (Pagreement did not change (kappa 0.38, pairwise agreement 60%). Our study is the first to validate the Paris classification for polyp morphology. We demonstrated only a moderate interobserver agreement among international Western experts for this classification system. Our data suggest that, in its current version, the use of this classification system in daily practice is questionable and it is unsuitable for comparative endoscopic research. We therefore suggest introduction of a simplification of the classification system.

[Development strategy of Paris based on combination of domestic patent and current resource application and development].

Science.gov (United States)

Zhao, Fei-Ya; Tao, Ai-En; Xia, Cong-Long

2018-01-01

Paris is a commonly used traditional Chinese medicine (TCM), and has antitumor, antibacterial, sedative, analgesic and hemostatic effects. It has been used as an ingredient of 81 Chinese patent medicines, with a wide application and large market demand. Based on the data retrieved from state Intellectual Property Office patent database, a comprehensive analysis was made on Paris patents, so as to explore the current features of Paris patents in the aspects of domestic patent output, development trend, technology field distribution, time dimension, technology growth rate and patent applicant, and reveal the development trend of China's Paris industry. In addition, based on the current Paris resource application and development, a sustainable, multi-channel and multi-level industrial development approach was built. According to the results, studies of Paris in China are at the rapid development period, with a good development trend. However, because wild Paris resources tend to be exhausted, the studies for artificial cultivation technology should be strengthened to promote the industrial development. Copyright© by the Chinese Pharmaceutical Association.

Present status of nuclear medicine - Situation in France

International Nuclear Information System (INIS)

Swiniarski, R. de

2002-01-01

Contrary to the general belief the nuclear medicine (NM) is a rather old science; actually, Henry Becquerel, the discoverer of the natural radioactivity in 1896, is deemed often as the initiator of this science and that would be the first stage. Discovery of artificial radioactivity by Irene and Frederic Joliot-Curie in 1934 marks the second essential stage and as such the initiation of NM. Nuclear medicine recorded significant progress since its inception, essentially after the WW1 due mainly to the advance of nuclear physics, nuclear electronics and the associated information techniques. But, the development of general physics boosted also other new methods of medical imaging as MRI (Magnetic Resonance Imaging), ultrasonic imaging, X-ray scanner, magnetic encephalography (MEG), etc. Several services of nuclear medicine currently functioning in France, in public or private hospitals, are all equipped at least with one Anger chamber, possibly two, what allows making the scintigraphy of most of human organs, or else, planar gamma-scintigraphy or tomo-scintigraphy. Unfortunately, regarding the positron chambers (positron computed tomography-PCT) the situation in France is not satisfactory. For the time being only three centres, particularly designed for research, are equipped with cyclotrons plus PCT technology, namely SHFJ at Orsay, Cyceron at Caen and SERMEP at Lyon (especially devoted to cardiologic investigation). Other two installations will be soon available at Toulouse and at Tenon (Paris). Officials, responsible of health services and medical schools and hospitals have defined a national index for PCT in France. Thus, starting from 2001, a machine for every million of inhabitants is provided, i.e. about 60 PCTs are planned to be installed till 2003 in Lille, Grenoble, Nantes, Rennes and other large French cities. France is committed not to miss the European bus of nuclear oncology of installing this equipment absolutely necessary in cancer detection and

The complete chloroplast genome of traditional Chinese medical plants Paris polyphylla var. yunnanensis.

Science.gov (United States)

Song, Yun; Xu, Jin; Chen, NaiZhong; Li, MingFu

2017-03-01

Paris polyphylla var. yunnanensis is a perennial medical plant widely used in traditional Chinese medicine. Here, we report the complete chloroplast genome of P. polyphylla var. yunnanensis. The genome is 157 675 bp in length including a small single-copy region (SSC, 18 319 bp) and a large single-copy region (LSC, 84 108 bp) separated by a pair of inverted repeats (IRs, 27 624 bp). The genome contained 115 genes, including 81 protein-coding genes, 4 ribosomal RNA genes, and 30 tRNA genes. Among these genes, 13 harbored a single intron and 2 contained a couple of introns. The overall G + C content of the cpDNA is 37.4%, while the corresponding values of the LSC, SSC, and IR regions are 35.71%, 31.43%, and 41.87%, respectively. A Maximum-likelihood phylogenetic analysis suggested that genus Trillium, Paris, Fritillaria, and Lilium were strongly supported as monophyletic and the P. polyphylla var. yunnanensis is closely related to Trillium.

Proceedings of the Eindhoven FASTAR Days 2004 : Eindhoven, The Netherlands, September 3-4, 2004

NARCIS (Netherlands)

Cleophas, L.G.W.A.; Watson, B.W.

2004-01-01

The Eindhoven FASTAR Days (EFD) 2004 were organized by the Software Construction group of the Department of Mathematics and Computer Science at the Technische Universiteit Eindhoven. On September 3rd and 4th 2004, over thirty participants|hailing from the Czech Republic, Finland, France, The

Use of experimental plots for assessing Chernobyl-derived fallout of {sup 137}CS in France

Energy Technology Data Exchange (ETDEWEB)

Bonte, Ph.; Sogon, S.; Bourgeois, S.; Terce, M.; Morel, Ch. [Laboratoire des Sciences du Climat et de l' Environnement, avenue de la Terrasse, 91 - Gif-sur-Yvette (France)

2004-07-01

Caesium-137 ({sup 137}Cs) is widely used for the determination of soil erosion and sedimentation rates. However, in Europe, if the additional inputs of {sup 137}Cs fallout associated with the Chernobyl accident have given a supplementary mark to know the chronological history of buried sediments in rivers or wetlands, they have considerably complicated the interpretation of {sup 137}Cs inventories used for estimating soil redistribution on slopes. In fact, determination of Chernobyl-derived fallout {sup 137}Cs is problematic because very few sites have been correctly sampled at the moment of the accident. During the ten years after, it was possible to estimate the fallout measuring the {sup 134}Cs activity for estimating {sup 137}Cs ({sup 137}Cs /{sup 134}Cs 2.0 at the time of the accident). But these measurements are extremely rare, whereas it should be the more accurate method to resolve this question. The more used solution is to use model based on atmospheric circulation and rain precipitation, the main part of fallout been due to atmospheric washing by the rain. Other solution is to compare {sup 137}Cs specific activity of soil samples collected after the accident and older samples. Then, we choose a set of soil samples collected on several experimental plots at different places in France, and sampled before and after the Chernobyl accident, to determine the part of contamination linked to this {sup 137}Cs fallout event with a simple comparison of their {sup 137}Cs specific activity. In fact, national French institutes working on agronomy maintain experimental plots, with varied surface area (1 m{sup 2} 10 m{sup 2} or larger), for monitoring of soil physics and chemistry evolution. Nine sites were studied: two of them close to Paris, one 100 km east of Paris, 3 in Loire basin and 3 in south west, in the Pyrenees Atlantic. These measurements confirm the influence of the Chernobyl radioactive plume over the Paris Basin concerning the {sup 137}Cs fallout. The

In vivo biodistribution and biological impact of injected carbon nanotubes using magnetic resonance techniques

Directory of Open Access Journals (Sweden)

Achraf Al Faraj

2011-02-01

Full Text Available Achraf Al Faraj1,2, Florence Fauvelle3, Nathalie Luciani4, Ghislaine Lacroix5, Michael Levy4, Yannick Crémillieux1, Emmanuelle Canet-Soulas1Université Lyon1, Créatis-LRMN, Lyon, France; 2King Saud University, College of Applied Medical Sciences, Radiological Sciences Department, Riyadh, Kingdom of Saudi Arabia; 3CRSSA, Biophysique Cellulaire et Moléculaire, Laboratoire de RMN, La Tronche, France; 4Université Paris7-Paris Diderot, Matières et Systèmes Complexes, Paris, France; 5Institut National de l’Environnement et des Risques Industriels, Verneuil-en-Halatte, FranceBackground: Single-walled carbon nanotubes (SWCNT hold promise for applications as contrast agents and target delivery carriers in the field of nanomedicine. When administered in vivo, their biodistribution and pharmacological profile needs to be fully characterized. The tissue distribution of carbon nanotubes and their potential impact on metabolism depend on their shape, coating, and metallic impurities. Because standard radiolabeled or fluorescently-labeled pharmaceuticals are not well suited for long-term in vivo follow-up of carbon nanotubes, alternative methods are required.Methods: In this study, noninvasive in vivo magnetic resonance imaging (MRI investigations combined with high-resolution magic angle spinning (HR-MAS, Raman spectroscopy, iron assays, and histological analysis ex vivo were proposed and applied to assess the biodistribution and biological impact of intravenously injected pristine (raw and purified and functionalized SWCNT in a 2-week longitudinal study. Iron impurities allowed raw detection of SWCNT in vivo by susceptibility-weighted MRI.Results: A transitional accumulation in the spleen and liver was observed by MRI. Raman spectroscopy, iron assays, and histological findings confirmed the MRI readouts. Moreover, no acute toxicological effect on the liver metabolic profile was observed using the HR-MAS technique, as confirmed by quantitative real

Atmospheric metal deposition in France: Estimation based on moss analysis. First results

International Nuclear Information System (INIS)

Galsomies, L.; Letrouit-Galinou, M.A.; Avnaim, M.; Duclaux, G.; Deschamps, C.; Savanne, D.

2000-01-01

The aim of this programme set up by University Pierre and Marie Curie-Paris VI and ADEME (French Agency for the Environment and Energy Management) is to obtain information on the atmospheric deposition of 36 elements (most being heavy metals) all over France, using 5 common mosses as bioaccumulators: Pleurozium schreberi, Hylocomium splendens, Hypnum cupressiforme, Scleropodium purum and Thuidium tamariscinum. Sampling was performed in 1996 from April to November thanks to 43 collectors. One sample of moss at least has been collected in 512 sites distributed over France, with an average density of one site each 1000 km 2 . Procedures for sampling, drying, cleaning, sorting are strictly codified based on Scandinavian guidelines. Analyses are performed according to two procedures: ICP-MS (Inductively Coupled Plasma, Mass Spectrometry) for Pb, Ni specialty and INAA (instrumental Neutron Activation Analysis for other elements. Data concerning As, Cd, Cr, Cu, Fe, Hg, Pb. Ni, V, Zn will be incorporated into the 1995-1996 European Programme 'Atmospheric Heavy Metal Deposition in Europe - estimation based on moss analysis' coordinated by the Nordic Council. The analyses are in progress, but preliminary results from Ile-de-France have been achieved for 34 elements in INAA. A preliminary study has shown that interspecies calibration could be possible for some heavy metals and that saturation effects in one species could be present when the intercalibration between species is not possible. Such a programme is made possible thanks to the financial support of the French Ministry of Environment and ADEME and with the active cooperation of several national organisations, especially the Laboratory Pierre Sue (CNRS-CEA). (author)

Psychosurgery for stuttering

Directory of Open Access Journals (Sweden)

Dur

2015-04-01

Full Text Available Edgar Durand,1 Alexander G Weil,2 Marc Lévêque1,3 1Espace éthique de l’Assistance publique-Hôpitaux de Paris et Département de recherche en éthique, South Paris University, Paris, France; 2Pediatric Neurosurgical Department, Sainte-Justine Hospital, Montreal, QC, Canada; 3Service de Neurochirurgie, Hôpital de la Pitié-Salpêtrière, Paris, France We read with interest the article entitled “Anterior capsulotomy improves persistent developmental stuttering with a psychiatric disorder: a case report and literature review” published in Neuropsychiatric Disease and Treatment.1 The authors report on a 28-year-old man with persistent developmental stuttering who was treated by bilateral anterior capsulotomy in the People’s Republic of China. To our knowledge, this is a new and previously unreported application of this technique for this indication. Accordingly, as the authors highlight, “the evidence for surgical treatment of persistent developmental stuttering and associated psychiatric disorders is limited”, placing their approach within the clinical research forum. In this experimental context, this case report brings forward several important reflections on patient evaluation, technique utilized, and postoperative follow-up. Read the original article

Resolution of foveal detachment in dome-shaped macula after treatment by spironolactone: report of two cases and mini-review of the literature

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Dirani A

2014-05-01

Full Text Available Ali Dirani,1 Alexandre Matet,1 Talal Beydoun,2 Irmela Mantel,1 Francine Behar-Cohen1–3 1Department of Ophthalmology, University of Lausanne, Jules Gonin Eye Hospital, Lausanne, Switzerland; 2Department of Ophthalmology, Hôtel-Dieu de Paris Hospital, Assistance Publique – Hôpitaux de Paris, Paris, France; 3Inserm UMRS872, Physiopathology of Ocular Diseases: Therapeutic Innovations, Centre de Recherche des Cordeliers, Paris, France Abstract: Dome-shaped macula (DSM was recently described in myopic patients as a convex protrusion of the macula within a posterior pole staphyloma. The pathogenesis of DSM and the development of associated serous foveal detachment (SFD remain unclear. The obstruction of choroidal outflow and compressive changes of choroidal capillaries have been proposed as causative factors. In this paper, we report two cases of patients with chronic SFD associated with DSM treated with oral spironolactone. After treatment, there was a complete resolution of SFD in both patients. To the best of our knowledge, this is the first report of successful treatment of SFD in DSM by a mineralocorticoid receptor antagonist. Keywords: serous foveal detachment, mineralocorticoid receptor antagonist, dome-shaped macula, treatment

The N4 CAD chain: Another electricite de France breakthrough in nuclear engineering

International Nuclear Information System (INIS)

Cornon, P.; Durey, P.

1996-01-01

With the previous pressurized water reactor (PWR) series (1300 MW), Electricite de France (EdF) has experienced the first chain of computer-aided design (CAD) tools from programming drawings to instrumentation and control microprocessor memories. The Engineering and Construction Division of EdF decided to integrate the CAD tools in the design and construction process of its new N4 series (1400-MW PWR). At that time, EdF determined four safety and data quality principles for the human/machine interface of the CAD: 1. Unique data capture: A common alphanumeric database shares all the information used by more than one application, so this information is typed only once and can be verified independently. 2. Intrinsic consistency: Added to the previous principle, data consistency is also ensured by every application that provides ways to enter only allowed data when it is possible. This is completed by some checking facilities. 3. Ergonomy: Making extensive use of windows, buttons, pictures, and wysiwyg facilities, the CAD section develops applications speaking the real language of every designer who is able to understand and verify her/his work. 4. On-line help: For any question, prompted by any application, some on-line help has been written giving the list of allowed answers with explanations and/or examples

Tour of France by foot

CERN Multimedia

Papini

1982-01-01

Monsieur Papini(nom juste?) et sa femme, tous les deux journalistes, découvrent avec leur 2 enfants, agés de 16 mois et 3 ans, ainsi qu'avec un âne, la vie nomade en parcourant la France pendant un an et demie à pied: comment être un nomade en France? Sa femme a écrit deux ouvrages concernant ce voyage.

Air quality in the mid-21st century for the city of Paris under two climate scenarios; from the regional to local scale

OpenAIRE

Markakis, K.; Valari, M.; Colette, A.; Sanchez, O.; Perrussel, O.; Honore, C.; Vautard, R.; Klimont, Z.; Rao, S.

2014-01-01

Ozone and PM2.5 concentrations over the city of Paris are modeled with the CHIMERE air-quality model at 4 km × 4 km horizontal resolution for two future emission scenarios. A high-resolution (1 km × 1 km) emission projection until 2020 for the greater Paris region is developed by local experts (AIRPARIF) and is further extended to year 2050 based on regional-scale emission projections developed by the Global Energy Assessment. Model evaluation is performed based on a 10-year...

Epidemiology, clinical, immune, and molecular profiles of microsporidiosis and cryptosporidiosis among HIV/AIDS patients

Directory of Open Access Journals (Sweden)

Wumba R

2012-07-01

Full Text Available Roger Wumba,1 Benjamin Longo-Mbenza,2 Jean Menotti,3,4 Madone Mandina,5 Fabien Kintoki,5 Nani Hippolyte Situakibanza,1,5 Marie Kapepela Kakicha,6 Josue Zanga,1 Kennedy Mbanzulu-Makola,1 Tommy Nseka,1 Jean Pierre Mukendi,1 Eric Kendjo,7 Jean Sala,1 Marc Thellier7,81Department of Tropical Medicine, Infectious and Parasitic Diseases, Department of Parasitology, University Clinic of Kinshasa, Faculty of Medicine, University of Kinshasa, Kinshasa, Congo; 2Faculty of Health Sciences, Walter Sisulu University, Eastern Cape, South Africa; 3Laboratory of Parasitology and Mycology, Saint-Louis Hospital, Public Assistance-Hospitals of Paris, Paris, France; 4Faculty of Medicine, Lariboisière-Saint-Louis, University of Paris VII, Paris, France; 5Department of Internal Medicine, University Clinic of Kinshasa, Faculty of Medicine, University of Kinshasa, Kinshasa, Congo; 6Department of Pediatrics, University Clinic of Kinshasa, Faculty of Medicine, University of Kinshasa, Kinshasa, Congo; 7National Center for Malaria Research, AP-HP, CHU Pitie Salpêtrière, Paris, France; 8Laboratory of Parasitology and Mycology, Pitié Salpêtrière Hospital, Public Assistance-Hospitals of Paris, Pierre and Marie Curie University, Paris, FranceBackground: The objective of this study was to determine the prevalence of intestinal parasites, with special emphasis on microsporidia and Cryptosporidium, as well as their association with human immunodeficiency virus (HIV symptoms, risk factors, and other digestive parasites. We also wish to determine the molecular biology definitions of the species and genotypes of microsporidia and Cryptosporidium in HIV patients.Methods: In this cross-sectional study, carried out in Kinshasa, Democratic Republic of the Congo, stool samples were collected from 242 HIV patients (87 men and 155 women with referred symptoms and risk factors for opportunistic intestinal parasites. The analysis of feces specimen were performed using Ziehl�

Reducing CO{sub 2} emissions fourfold in France by 2050. Introduction to the debate; La division par 4 des emissions de dioxyde de carbone en France d'ici 2050. Introduction au debat

Energy Technology Data Exchange (ETDEWEB)

NONE

2004-07-01

In light of the aforementioned IPCC report, and in order to limit the impacts of climate change on planet Earth, we conclude that it is necessary to reduce carbon dioxide concentrations in the atmosphere to less than 450 parts per million by volume (ppmv). Given the historic responsibility of the first industrial nations, and so that meeting this target does not ruin the development prospects of Southern hemisphere countries, the twofold reduction target means that industrialized countries must aim for a fourfold reduction of greenhouse gas emissions by 2050. As the French Prime Minister declared on 19 February 2003 at the opening of IPCC 20. plenary session in Paris, France has set itself on this course. Bearing in mind the nature of the phenomenon, only those policies that are resolutely long-term will be of relevance here. Implementing them assumes that, in order to inform possible choices, different energy consumption scenarios for 2050 in each of the major economic sectors emitting GHGs will have been clearly analysed. Such is the aim of this study conducted by the French Inter-ministerial Task Force on Climate Change (MIES). The study emphasises that it is absolutely imperative to pursue efforts undertaken in order to reach maximum energy efficiency in all sectors, to significantly reduce oil consumption in the transport sector and to rapidly increase energy production from renewable. Lastly, the study stresses the complementary role that technological progress can play. (A.L.B.)

Paris Conference (Further report)

International Nuclear Information System (INIS)

Anon.

1982-01-01

From 26-31 July, the international particle physics community met for its traditional biennial 'Rochester' jamboree, held this time in Paris. While there were no major physics surprises, there was still plenty of interest for all and the ground that was covered amply demonstrated the progress which has been made since the previous round of international meetings. The emphasis is very much on improving the already considerable level of agreement between different experiments and between experimental results and theoretical predictions

Um olhar de descoberta na Paris da Belle Époque

Directory of Open Access Journals (Sweden)

João Carrascoza

2008-09-01

Full Text Available Ao estilo dos textos de Baudelaire sobre os flâneurs que caminhavam na cidade de Paris, descobrindo os símbolos da modernidade, este artigo narra a chegada de um estrangeiro à capital francesa no início do século XX e seu passeio pela cidade. Ao longo de um dia, ele tomará contato com as obras de importantes artistas como Toulouse-Lautrec, Murcha e Chéret, que desenharam cartazes para shows, embalagens de produtos, folhetos promocionais, entre outras manifestações artísticas exploradas pelo então nascente espírito moderno. À semelhança do romance de Umberto Eco, A misteriosa chama da rainha Loana, que reproduz imagens da cultura pop e erudita em meio à sua narrativa, o texto segue o formato de ensaio ilustrado, fundindo a ficção com os aspectos reais da Paris na efervescência da Belle Époque. A estrutura, portanto, rompe com os gêneros tradicionais dos artigos acadêmicos, apresentando conteúdo reflexivo por meios dos personagens e da trama engendrada. Palavras-chave: Paris; Belle Époque; modernidade; imagens; publicidade. ABSTRACT In the style of Baudelaire’s texts on the flâneurs who used to walk in the city of Paris, finding the symbols of modernity, this article narrates the ar- rival of a foreigner in the early 20th century in Paris, and his tour around the French capital. In the course of one day, he will be in contact with the works of important artists, such as Toulouse-Lautrec, Murcha and Chéret, who drew posters for shows, products’ packages, advertising leaflets, among other artistic manifestations, explored by the then rising modern spirit. Similar to Umberto Eco’s novel The mysterious flame of Queen Loana, which reproduces images of both pop and erudite culture in its narrative, the text follows the illustrated essay format, merging fiction and the real aspects of Paris’ effervescent Belle Époque. The structure, therefore, breaks free from the traditional genres of academic articles, presenting the

Foreign driving licences in France

CERN Multimedia

HR Department

2009-01-01

The following information is subject to possible amendments decided by the competent French authorities. Those wishing to undertake the necessary steps with the prefectural services of the Departments of the Ain and Haute-Savoie may obtain information by calling the following numbers: + 33 4 74 32 30 65 for the Ain and + 33 4 50 33 60 00 for Haute-Savoie. 1. PERSONS RESIDING IN FRANCE 1.1 Driving licences issued by a State belonging to the EU or the EEA a) Recognition on French territory All currently valid driving licences issued by States belonging to the European Union (EU) or to the European Economic Area (EEA) are generally valid for driving on French territory. However, if the licence was originally obtained in exchange for a licence issued by a State not belonging to the EU or to the EEA and with which France has not concluded a reciprocity agreement, it will be recognised for a maximum of one year following the date of establishment of normal residence in France ...

China's response to climate change issues after Paris Climate Change Conference

Directory of Open Access Journals (Sweden)

Yun Gao

2016-12-01

Full Text Available The Paris Climate Change Conference was successfully concluded with the Paris Agreement, which is a milestone for the world in collectively combating climate change. By participating in IPCC assessments and conducting national climate change assessments, China has been increasing its understanding of the issue. For the first time, China's top leader attended the Conference of the Parties, which indicates the acknowledgement of the rationality and necessity of climate change response by China at different levels. Moreover, this participation reflects China's commitment to including climate change in its ecology improvement program and pursuing a low-carbon society and economy. In order to ensure the success of the Paris Conference, China has contributed significantly. China's constructive participation in global governance shows that China is a responsible power. These principles such as the creation of a future of win–win cooperation with each country contributing to the best of its ability; a future of the rule of law, fairness, and justice; and a future of inclusiveness, mutual learning, and common development will serve as China's guidelines in its efforts to facilitate the implementation of the Paris Agreement and participate in the design of international systems.

China's response to climate change issues after Paris Climate Change Conference

Institute of Scientific and Technical Information of China (English)

GAO Yun

2016-01-01

The Paris Climate Change Conference was successfully concluded with the Paris Agreement, which is a milestone for the world in collectively combating climate change. By participating in IPCC assessments and conducting national climate change assessments, China has been increasing its understanding of the issue. For the first time, China's top leader attended the Conference of the Parties, which indicates the acknowledgement of the rationality and necessity of climate change response by China at different levels. Moreover, this participation reflects China's commitment to including climate change in its ecology improvement program and pursuing a low-carbon society and economy. In order to ensure the success of the Paris Conference, China has contributed significantly. China's constructive participation in global governance shows that China is a responsible power. These principles such as the creation of a future of winewin cooperation with each country contributing to the best of its ability;a future of the rule of law, fairness, and justice;and a future of inclusiveness, mutual learning, and common development will serve as China's guidelines in its efforts to facilitate the implementation of the Paris Agreement and participate in the design of international systems.

Air pollution and doctors' house calls for respiratory diseases in the Greater Paris area (2000-3).

Science.gov (United States)

Chardon, Benoit; Lefranc, Agnès; Granados, Denis; Grémy, Isabelle

2007-05-01

This study describes the short-term relationships between the daily levels of PM10, PM2.5, NO2 and the number of doctors' house calls for asthma, upper respiratory diseases (URD) and lower respiratory diseases (LRD) in Greater Paris for the years 2000-3. Doctors' house calls are a relevant health indicator for the study of short-term health effects of air pollution. Indeed, it is potentially more sensitive than indicators such as general hospital admissions due to the severity of diseases motivating the call. In this study, time-series analysis was used. The daily numbers of doctor's house calls were adjusted for time trends, seasonal factors, day of the week, influenza, weather and pollen. Up to 15 days of lag between exposure and health effects was considered using distributed lag models. A total of about 1,760,000 doctors' house calls for all causes occurred during the study period, among which 8027 were for asthma, 52,928 for LRD and 74,845 for URD. No significant increase in risk was found between air pollution and doctors' house calls for asthma. No significant association was found between NO2 and doctors' house calls. An increase of 10 microg/m3 in the mean levels of PM10 and PM2.5 encountered during the 3 previous days was associated with an increase of 3% (0.8% and 5.3%) and 5.9% (2.9% and 9.0%) in the number of doctor's house calls for URD and LRD, respectively. Considering up to 15 days between exposure and health outcomes, effects persist until 4 days after exposure and then decrease progressively. No morbidity displacement was observed. This study shows a significant heath effect of ambient particles (PM2.5 and PM10). When compared to the RRs obtained for mortality or hospital admissions in the same area, the values of the RRs obtained in this study confirm the higher sensibility of doctor's house calls for respiratory diseases as a health indicator.

Prevalence and circumstances of forced sex and post-migration HIV acquisition in sub-Saharan African migrant women in France: an analysis of the ANRS-PARCOURS retrospective population-based study.

Science.gov (United States)

Pannetier, Julie; Ravalihasy, Andrainolo; Lydié, Nathalie; Lert, France; Desgrées du Loû, Annabel

2018-01-01

Sub-Saharan African migrant women are a key population at risk of HIV infection in Europe. Using data from the ANRS-PARCOURS study, we aimed to assess the prevalence of forced sex after migration and its association with post-migration acquisition of HIV as well as the circumstances of forced sex after migration, including housing and administrative insecurity, among sub-Saharan African migrant women living in the Paris Region, France. The ANRS-PARCOURS study was a retrospective life-event survey done between February, 2012, and May, 2013, in health-care facilities in the Paris region of France. Women were eligible if they were born in sub-Saharan Africa, aged between 18 and 59 years, and had been diagnosed with HIV infection at least 3 months earlier for women receiving HIV care or not diagnosed with HIV. In this analysis, we used ANRS-PARCOURS study data to compare the incidence of forced sex after migration in three groups of sub-Saharan African migrant women: those who acquired HIV after migrating, those who acquired HIV before migrating, and those without HIV. We assessed the associations between forced sex, sexual partnerships, and living conditions after migration with mixed-effects logistic regression and generalised structural equation models. The study is registered with ClinicalTrials.gov, number NCT02566148. We obtained data from 980 eligible individuals who participated in the ANRS-PARCOURS study (407 without HIV and 573 HIV-positive) from 54 randomly selected health-care facilities. We excluded 20 women whose HIV infection could not be dated and eight women with missing data from the analyses, for a total of 405 women in the reference group (without HIV) and 547 women in the HIV group (156 with post-migration HIV acquisition, 391 with pre-migration HIV). Women who acquired HIV after migration experienced forced sex after migration more frequently than women without HIV (24 [15%] vs 18 [4%]; p=0·001). Forced sex after migration was associated with

High-resolution inventory of NO emissions from agricultural soils over the Ile-de-France region

Energy Technology Data Exchange (ETDEWEB)

Rolland, M.-N. [INRA, AgroParisTech, UMR 1091 Environnement et Grandes Cultures, F-78850 Grignon (France); Gabrielle, B., E-mail: Benoit.Gabrielle@agroparistech.f [INRA, AgroParisTech, UMR 1091 Environnement et Grandes Cultures, F-78850 Grignon (France); Laville, P.; Cellier, P. [INRA, AgroParisTech, UMR 1091 Environnement et Grandes Cultures, F-78850 Grignon (France); Beekmann, M. [Laboratoire Inter-universitaire des Systemes Atmospheriques - CNRS, Universites Paris-Est and Paris 7, F-94 010 Creteil (France); Gilliot, J.-M.; Michelin, J.; Hadjar, D. [INRA, AgroParisTech, UMR 1091 Environnement et Grandes Cultures, F-78850 Grignon (France); Curci, G. [Dipartimento di Fisica - CETEMPS, Universita' degli Studi dell' Aquila, 67010 Coppito, L' Aquila (Italy)

2010-03-15

Arable soils are a significant source of nitric oxide (NO), a precursor of tropospheric ozone, and thereby contribute to ozone pollution. However, their actual impact on ozone formation is strongly related to their spatial and temporal emission patterns, which warrant high-resolution estimates. Here, we combined an agro-ecosystem model and geo-referenced databases to map these sources over the 12 000 km{sup 2} administrative region surrounding Paris, France, with a kilometric level resolution. The six most frequent arable crop species were simulated, with emission rates ranging from 1.4 kg N-NO ha{sup -1} yr{sup -1} to 11.1 kg N-NO ha{sup -1} yr{sup -1}. The overall emission factor for fertilizer-derived NO emissions was 1.7%, while background emissions contributed half of the total NO efflux. Emissions were strongly seasonal, being highest in spring due to fertilizer inputs. They were mostly sensitive to soil type, crops' growing season and fertilizer N rates. - The use of an agro-ecosystem model at regional scale makes it possible to map the emissions of nitric oxide from arable soils at a resolution compatible with tropospheric ozone models.

New Maids and Caretakers in Paris?: The Reactivation of Transnational Social Fields of Spanish Emigration Following the Economic Crisis

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Laura Oso

2017-12-01

Full Text Available This article analyses the migration of Spanish women to France following the 2008 economic crisis, considering the reactivation of the transnational social fields that have been built up between the two countries over the years. It reveals how the recession has led to a renewal of the gender-based labour niches filled by women emigrating to Paris in the period between 1950 and 1970 (bonnes à tout faire or maid, domestic workers, caretakers and cleaners, stemming from the reactivation of transnational fields built up through social networks woven by the various migratory trends. It provides an insight into the way these transnational fields are linked to global production and reproduction chains in terms of the patriarchal reorganisation of the labour market and workforce. It concludes that the economic crisis has reinforced traditional social reproduction channels rooted in gender-based sources of employment.

Diurnal, synoptic and seasonal variability of atmospheric CO2 in the Paris megacity area

Science.gov (United States)

Xueref-Remy, Irène; Dieudonné, Elsa; Vuillemin, Cyrille; Lopez, Morgan; Lac, Christine; Schmidt, Martina; Delmotte, Marc; Chevallier, Frédéric; Ravetta, François; Perrussel, Olivier; Ciais, Philippe; Bréon, François-Marie; Broquet, Grégoire; Ramonet, Michel; Spain, T. Gerard; Ampe, Christophe

2018-03-01

Most of the global fossil fuel CO2 emissions arise from urbanized and industrialized areas. Bottom-up inventories quantify them but with large uncertainties. In 2010-2011, the first atmospheric in situ CO2 measurement network for Paris, the capital of France, began operating with the aim of monitoring the regional atmospheric impact of the emissions coming from this megacity. Five stations sampled air along a northeast-southwest axis that corresponds to the direction of the dominant winds. Two stations are classified as rural (Traînou - TRN; Montgé-en-Goële - MON), two are peri-urban (Gonesse - GON; Gif-sur-Yvette - GIF) and one is urban (EIF, located on top of the Eiffel Tower). In this study, we analyze the diurnal, synoptic and seasonal variability of the in situ CO2 measurements over nearly 1 year (8 August 2010-13 July 2011). We compare these datasets with remote CO2 measurements made at Mace Head (MHD) on the Atlantic coast of Ireland and support our analysis with atmospheric boundary layer height (ABLH) observations made in the center of Paris and with both modeled and observed meteorological fields. The average hourly CO2 diurnal cycles observed at the regional stations are mostly driven by the CO2 biospheric cycle, the ABLH cycle and the proximity to urban CO2 emissions. Differences of several µmol mol-1 (ppm) can be observed from one regional site to the other. The more the site is surrounded by urban sources (mostly residential and commercial heating, and traffic), the more the CO2 concentration is elevated, as is the associated variability which reflects the variability of the urban sources. Furthermore, two sites with inlets high above ground level (EIF and TRN) show a phase shift of the CO2 diurnal cycle of a few hours compared to lower sites due to a strong coupling with the boundary layer diurnal cycle. As a consequence, the existence of a CO2 vertical gradient above Paris can be inferred, whose amplitude depends on the time of the day and on

Robustness of Electrical Systems of Nuclear Power Plants in Light of the Fukushima Daiichi Accident (ROBELSYS). Workshop Proceedings, Paris, France, 1-4 April 2014 - Robustness of Electrical Systems of NPP's in Light of the Fukushima Daiichi Accident. ROBELSYS Workshop Proceedings

International Nuclear Information System (INIS)

2015-01-01

The March 2011 accident at Fukushima Daiichi triggered discussions about the significance of electrical power hazards and their treatment in safety analyses. In order to address these issues and provide relevant conclusions and recommendations to CSNI and CNRA, the Robustness in Electrical Systems (ROBELSYS) Technical Working Group was established in 2012 under the leadership of the Institut de Radioprotection et de Surete Nucleaire (IRSN) of France. The purpose of the ROBELSYS Technical Working Group was to organize an international workshop to identify and discuss the lessons learned from the Fukushima Daiichi accident. The workshop was focused on the provisions taken by various countries concerning national requirements and modifications to the plant designs in order to enhance the robustness of electrical systems, especially the protection against extreme external hazards. The ROBELSYS workshop was held at the OECD Conference Centre in Paris in April 1-4, 2014. A total of 105 participants attended the workshop representing industry and government organisations from 25 countries, as well as international organisations. A total of 34 technical presentations were given in seven sessions as follows: - 1: National Programmes on Evolution of Onsite and Offsite Electric Power Systems; - 2: Role of Electric Power in Severe Accident Management; - 3: Requirements for Robustness of Onsite Electric Power Systems; - 4: Simulation of Transients within NPP Plant Distribution Systems; - 5: Requirements for Equipment Used for Emergency Response; - 6: Margin Assessments for Modern Power Electronics; - 7: Digital Components in Power Systems. Items addressed in the workshop included: - Review of the lessons learned from the Fukushima accident concerning the robustness of electrical systems; - Review of the provisions already taken or planned after the Fukushima accident, regarding the sources, the distribution systems and the loads, and documenting the technical basis for these

Identifying and Overcoming Barriers to Effective Consideration of Human and Organisational Factors in Event Analysis and Root Cause Analysis. Workshop Proceedings, September 21-22, 2009, Paris, France

International Nuclear Information System (INIS)

2011-01-01

Nuclear licensees must have effective processes for learning from operating experience in order to manage safety, secure continuous improvement and defend against the potential for repeat events. These processes include root cause analysis (RCA) to identify the underlying causes of events and mechanisms to learn from these analyses and to implement improvements. Correctly identifying and correcting the causes of events will allow lessons to be learned and shared with others in the industry. The treatment of Human and Organisational Factors (HOF) in RCA is of special interest to WGHOF. It is estimated that approximately 60-80% of events in the nuclear industry can be attributed to human and organisational factors. Although the importance of correctly identifying the HOF causes is understood, there is still a tendency for the analysis to focus solely on the technical issues of the event. The history of prominent events across the major hazards sector shows that HOF lessons often fail to be learned. A NEA/CSNI special experts meeting entitled 'Identification of Barriers to Analyzing and Identifying Human and Organisational Factors in Root Cause Analysis' was held at the NEA Headquarters in Paris, France on September 21-22, 2009. A total of 17 participants from 10 countries representing licensee organisations, regulators, international organisations and an independent consultant attended the meeting. The meeting was structured to allow for small group discussions during which a number of themes were explored, followed by plenary discussion. There were also four papers presented which complemented the discussion themes. As set out in the objectives of this work, the participants identified barriers to the effective treatment of HOF in RCA and recommendations to mitigate the effects of these barriers. Many of the barriers and recommendations identified relate to the RCA process in general, not specifically to the treatment of HOF in the RCA process. This is logical, for

Low-energy neutron-proton analyzing power and the new Bonn potential and Paris potential predictions

International Nuclear Information System (INIS)

Tornow, W.; Howell, C.R.; Roberts, M.L.; Felsher, P.D.; Chen, Z.M.; Walter, R.L.; Mertens, G.; Slaus, I.

1988-01-01

Instrumental asymmetries recently observed by Haeberli and co-workers, limit the accuracy of neutron-proton analyzing power A/sub y/(θ) data. These instrumental effects are discussed and calculated for previously published n-p A/sub y/(θ) data at 16.9 MeV. To enable these calculations, the analyzing power for the 2 H(d-arrow-right,n) 3 He reaction was measured at small angles. Additional n-p A/sub y/(θ) data at extreme backward angles, obtained via proton recoil detection, are also reported for this energy in this paper. The composite data set is compared to calculations based on the new Bonn NN potential, the Paris NN potential, and to the recent NN phase-shift solution of Arndt. In addition, a detailed comparison between A/sub y/(θ) calculated from the new Bonn and the Paris potentials between 10 and 50 MeV is shown to reveal unexpectedly large relative differences. The experimental data in this energy range are better described by the Paris potential than by the new Bonn potential

Driving factors of temporary and permanent shallow lakes in and ...

African Journals Online (AJOL)

2018-04-02

Apr 2, 2018 ... Paris-Sud, CNRS, AgroParisTech, Université Paris-Saclay, Orsay, France. 5Zone Atelier ... Received 7 August 2015; accepted in revised form 12 March 2018 ...... pollution on the water quality of the turbid Modder River. Water.

Spectacle independence and subjective satisfaction of ReSTOR® multifocal intraocular lens after cataract or presbyopia surgery in two European countries

Directory of Open Access Journals (Sweden)

Béatrice Cochener

2010-02-01

Full Text Available Béatrice Cochener1, Luis Fernández-Vega2, Jose F Alfonso2, Frédérique Maurel3, Juliette Meunier4, Gilles Berdeaux5,61Centre Hospitalier de Brest, Brest, France; 2Instituto Oftalmologico Fernandez Vega, Oviedo, Spain; 3IMS Health, Health Economics Department, Puteaux, France; 4Mapi Values, Lyon, France; 5Alcon France, Health Economics Department, Rueil-Malmaison, France; 6Conservatoire National des Arts et Métiers, Paris, FrancePurpose: To determine the percentage of patients implanted bilaterally with ReSTOR® requiring spectacles at 18 months, the patient satisfaction, and factors that predict spectacles independence.Methods: The medical and surgical data were collected from patient records. The ‘Freedom from Spectacles Value Scale’ (FGVS was used to rank their experiences via telephone interview. A Bayesian network was used to predict postoperative spectacles use.Results: 304 patients (65.6 years were included. Postoperative visual acuity was ≥0.8 in 93.3% of patients for near vision and in 88.6% of patients for distance vision. After surgery, 87.2% of the patients were spectacles free. 88.2% of the patients rated their vision as being better following the surgery and 93.1% thought that surgery resulted in a positive change. FGVS mean scores (5 the most favorable rating were: ‘Practical Advantages’ 3.8, ‘Psychological Advantages’ 3.8, ‘Evaluation of the Result’ 4.5, ‘Feelings’ 4.4, and ‘Global Judgement’ 4.4. Patients who stated that spectacles wear was particularly bothersome and those who thought that their appearance was more favorable without spectacles were 3 times more likely not to wear spectacles postoperatively.Conclusion: ReSTOR® provides patients with good distance and near vision, a high rate of spectacles independence, and a high degree of patient satisfaction.Keywords: cataract surgery, multifocal intraocular lens, patient satisfaction, spectacles independence

Social vulnerabilities and health conditions of arrestees in the Greater Paris area, France, in 2013: a multicentre cross-sectional study.

Science.gov (United States)

Verdier, Emilie; Denis, Céline; Bourokba, Nacer; Chauvin, Pierre; Chariot, Patrick

2018-05-01

The aim of this study was to describe the health and social conditions of arrestees, as compared to the general population. We studied a sample of 600 adult arrestees in three locations in the Greater Paris area, prospectively included (February-May 2013). A descriptive analysis has been performed, then prevalence was estimated using an indirect standardisation according to age, based on data from a population-based, representative survey in the same area. Arrestees had a median age of 31 years; 92% were males. As compared to the general population, arrestees had a lower level of education (8.6 vs. 7.6%, p analysis of male arrestees and males from the general population showed that the former had worse social and health conditions. These results argue for widespread medical interventions on all arrestees. Medical examination during detention could act as a gateway to health care and social support.

Reducing CO{sub 2} emissions fourfold in France by 2050. Introduction to the debate; La division par 4 des emissions de dioxyde de carbone en France d'ici 2050. Introduction au debat

Energy Technology Data Exchange (ETDEWEB)

NONE

2004-07-01

In light of the aforementioned IPCC report, and in order to limit the impacts of climate change on planet Earth, we conclude that it is necessary to reduce carbon dioxide concentrations in the atmosphere to less than 450 parts per million by volume (ppmv). Given the historic responsibility of the first industrial nations, and so that meeting this target does not ruin the development prospects of Southern hemisphere countries, the twofold reduction target means that industrialized countries must aim for a fourfold reduction of greenhouse gas emissions by 2050. As the French Prime Minister declared on 19 February 2003 at the opening of IPCC 20. plenary session in Paris, France has set itself on this course. Bearing in mind the nature of the phenomenon, only those policies that are resolutely long-term will be of relevance here. Implementing them assumes that, in order to inform possible choices, different energy consumption scenarios for 2050 in each of the major economic sectors emitting GHGs will have been clearly analysed. Such is the aim of this study conducted by the French Inter-ministerial Task Force on Climate Change (MIES). The study emphasises that it is absolutely imperative to pursue efforts undertaken in order to reach maximum energy efficiency in all sectors, to significantly reduce oil consumption in the transport sector and to rapidly increase energy production from renewable. Lastly, the study stresses the complementary role that technological progress can play. (A.L.B.)

Events - France. Stock exchange. International; Actualite - France. Bourse. International

Energy Technology Data Exchange (ETDEWEB)

Anon,

2000-10-01

These columns made of short articles report on facts and events in the oil and gas industry in France and worldwide: 1 - France: increase of the production capacity of the ethylene oxide unit of BP's Lavera plant; the 'Plateaux-du-Vexin' gas pipeline crosses the Seine river; completion of the pumping of the front wreckage of the Erika tanker ship; Total inaugurates a vapor recovery unit at the Gonfreville l'Orcher refinery; a national energy saving plan for the abatement of the greenhouse effect; Sercel, a daughter company of Compagnie Generale de Geophysique (CGG), acquires Mark Products division of Shaw industries; the oil prices shoot the international trade; 2 - stock exchange: trend of market values in the context of oil crisis; 3 - international: important oil and gas strike made by TotalFinaElf and OKIOC (Offshore Kazakhstan International Operating Company) in Kazakhstan; communication: a new look for BP; status of Lukoil reserves in Russia; next round for the exploration of the Norwegian North Sea; Transocean Sedco Forex absorbs R and B Falcon Corp and becomes the first drilling contractor; ENI (Italy) becomes operator on the development of South Pars gas field (Iran) for the phases 4 and 5; Shell Overseas Investments BV, BP and Exxon Mobil have signed strategic alliance agreements with China Petroleum and Chemical Corp (Sinopec); first exploration permits for the Faeroe islands; different gas pricing rules for the industrialists in the different European countries. (J.S.)

Events - France. Stock exchange. International; Actualite - France. Bourse. International

Energy Technology Data Exchange (ETDEWEB)

Anon.

2000-10-01

These columns made of short articles report on facts and events in the oil and gas industry in France and worldwide: 1 - France: increase of the production capacity of the ethylene oxide unit of BP's Lavera plant; the 'Plateaux-du-Vexin' gas pipeline crosses the Seine river; completion of the pumping of the front wreckage of the Erika tanker ship; Total inaugurates a vapor recovery unit at the Gonfreville l'Orcher refinery; a national energy saving plan for the abatement of the greenhouse effect; Sercel, a daughter company of Compagnie Generale de Geophysique (CGG), acquires Mark Products division of Shaw industries; the oil prices shoot the international trade; 2 - stock exchange: trend of market values in the context of oil crisis; 3 - international: important oil and gas strike made by TotalFinaElf and OKIOC (Offshore Kazakhstan International Operating Company) in Kazakhstan; communication: a new look for BP; status of Lukoil reserves in Russia; next round for the exploration of the Norwegian North Sea; Transocean Sedco Forex absorbs R and B Falcon Corp and becomes the first drilling contractor; ENI (Italy) becomes operator on the development of South Pars gas field (Iran) for the phases 4 and 5; Shell Overseas Investments BV, BP and Exxon Mobil have signed strategic alliance agreements with China Petroleum and Chemical Corp (Sinopec); first exploration permits for the Faeroe islands; different gas pricing rules for the industrialists in the different European countries. (J.S.)

International Neural Network Society Annual Meeting (1994) Held in San Diego, California on 5-9 June 1994. Volume 3.

Science.gov (United States)

1994-06-09

PROBLEM BASED ON LEARNING IN THE RECURRENT RANDOM NEURAL NETWORK Jose AGUILAR EHEI. UFR de Mathematiques et d’Informatique. Universiti Rene Descartes 45...parallelisme optimal". PHD thesis. Rene Descartes University, Paris, France, 1992. 9. GELENBE, E. "Learning in the recurrent Random Neural Network", Neural

Paris convention - Decisions, recommendations, interpretations

International Nuclear Information System (INIS)

1990-01-01

This booklet is published in a single edition in English and French. It contains decisions, recommendations and interpretations concerning the 1960 Paris Convention on Third Party Liability in the Field of Nuclear Energy adopted by the OECD Steering Committee and the OECD Council. All the instruments are set out according to the Article of the Convention to which they relate and explanatory notes are added where necessary [fr

cis- and trans-2,3,3a,4,5,9b-Hexahydro-1H-benz[e]indoles: synthesis and evaluation of dopamine D2, and D3 receptor binding affinity

DEFF Research Database (Denmark)

Song, Xiaodong; Crider, Michael A.; Cruse, Sharon F.

1999-01-01

cis- and trans-2,3,3a,4,5,9b-hexahydro-1H-benz [e]indoles were synthesized as conformationally rigid analogues of 3-phenylpyrrolidine and evaluated for dopamine (DA) D2S and D3 receptor binding affinity. The tricyclic benz[e]indole nucleus was constructed by a previously reported reductive...... configuration. These novel ligands may be useful tools for gaining additional information about the DA D3 receptor. Copyright Elsevier, Paris.dopamine / D2S receptor / D3 receptor / cis- and trans-2,3,3a,4,5,9b-hexahydro-1H-benz[e]indoles / receptor binding affinity....... receptors was shown by compounds substituted with N-n-propyl or N-allyl groups. The cis-(+-)-N-allyl derivative 21e demonstrated a D2S/D3 selectivity of 290. Resolution of cis-(+-)-5 and trans-(+-)- 21c into individual enantiomers showed that in both series the more active isomer had 3aR absolute...

Unexpected {delta}{sup 18}O and {delta}{sup 2}H Variability of Groundwater in the Eastern Paris Basin

Energy Technology Data Exchange (ETDEWEB)

Gourcy, L.; Petelet-Giraud, E. [BRGM Service EAU, Orleans (France)

2013-07-15

The Paris Basin covers about one-third of the total surface area of France. In 2009, two campaigns sampling 25 boreholes tapping Tertiary aquifers were carried out in the Basin. These aquifers are recharged at a similar altitude and the groundwater age is too young to have registered climate change. In the past, regional studies included the use of isotopes to understand groundwater origin and dynamics. Both {delta}{sup 18}O and {delta}{sup 2}H as well as ages (CFC/SF{sub 6)} and chemical components were determined in all collected samples. A noticeable stable isotope 'anomaly' appears in the south-western part of the Basin, where the average {delta}{sup 18}O and {delta}{sup 2}H values are more depleted and do not fit the pattern given by the continental effect in this area. A regional particularity of the spatial distribution of such isotopes in precipitation may be possible, but should be confirmed by additional work. (author)

Major bleeding complications in patients treated with direct oral anticoagulants: One-year observational study in a Paris Hospital.

Science.gov (United States)

Deville, L; Konan, M; Hij, A; Goldwirt, L; Peyrony, O; Fieux, F; Faure, P; Madelaine, I; Villiers, S; Farge-Bancel, D; Frère, C

Direct oral anticoagulants (DAOC) are indicated for the treatment of venous thromboembolism and the prevention of stroke or systemic embolism in patients with non-valvular atrial fibrillation. Given their advantages and friendly use for patient, the prescription of long term DOAC therapy has rapidly increased both as first line treatment while initiating anticoagulation and as a substitute to vitamins K antagonist (VKA) in poorly controlled patients. However, DOAC therapy can also be associated with significant bleeding complications, and in the absence of specific antidote at disposal, treatment of serious hemorrhagic complications under DOAC remains complex. We report and discuss herein five cases of major hemorrhagic complications under DOAC, which were reported to the pharmacological surveillance department over one year at Saint-Louis University Hospital (Paris, France). We further discuss the need for careful assessment of the risk/benefit ratio at time of starting DOAC therapy in daily clinical practice. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

Tracing transfer processes of metal pollutants from soils to surface water using environmental magnetic techniques - results from Paris suburbia (France)

Science.gov (United States)

Franke, Christine; Lamy, Isabelle; van Oort, Folkert; Thiesson, Julien; Barsalini, Luca

2015-04-01

Major river systems in Europe are potential sinks for environmental pollutions and therefore reflect the consequences of European industrialization and urbanization. Surface water pollution is a major concern for the health of the population and its related ecosystems as well as for the water quality. Within the variety of different typical pollutants in a river watershed, the metallic fraction embraces many toxic/dangerous contaminants. Each of these elements comprises different sources and follows specific processes throughout its pathways from its origin to and within the river system. But the detection, estimation and follow up of the different contaminants is highly complex. Physico-chemical techniques such as environmental and rock magnetics are powerful complementary tools to traditional methods because they comprise the possibility to trace the entire metal fraction and do offer the possibility to perform spatio-temporal analyze campaigns directly in the field and on a relative high number of samples from both the river and the adjacent areas (suspended particular matter, soils, dust, sediments, etc). In this study, we took advantages of the recent results on the Seine river (France) that have shown the high potential of environmental magnetic methods to estimate the metal fraction in suspended particular matter samples, and to allow the discrimination of its natural detrital, biogenic or anthropogenic origin (see parallel EGU abstract of Kayvantash et al. in this session). We focused on a suburban agricultural area west of Paris (Pierrelaye-Bessancourt) adjacent to the Seine river, which suffers from a high accumulation of heavy metal pollutants caused by long-term historical irrigation with urban waste waters. For the time being, these heavy metals seem to be geochemically fixed in the surface layer mainly by the soil organic matter. Future land use planning, however, arises questions on the fate of these pollutants and their potential remobilization by

The legal character and operational relevance of the Paris Agreement's temperature goal

Science.gov (United States)

Rajamani, Lavanya; Werksman, Jacob

2018-05-01

This article assesses the legal character and operational relevance of the Paris Agreement's 1.5°C temperature goal. This article begins with a textual analysis of the 1.5°C goal. It considers whether the goal creates individual or collective obligations for Parties, and whether it is sufficiently specific to enable the tracking of individual or collective performance. Next, it assesses the operational relevance of the 1.5°C temperature goal, by considering the role it will play in the Paris Agreement's institutions and procedures. To the extent that the goal plays a role, and implies global limits on greenhouse gas emissions, this article observes that it could have implications for the sharing of the effort between Parties. Thus, this article considers the relevance of equity and the principle of common but differentiated responsibilities and respective capabilities, in the light of different national circumstances, to understanding how the 1.5°C goal could be reached. In this context, this article explores whether the 1.5°C goal could play a role in the Paris Agreement's `ambition cycle'. Finally, this article asks whether there are any legal or political implications, individually or collectively under the Paris Agreement, should the Parties fail to achieve the 1.5°C goal. This article is part of the theme issue `The Paris Agreement: understanding the physical and social challenges for a warming world of 1.5°C above pre-industrial levels'.

Nuclear safety in France in 2001

International Nuclear Information System (INIS)

Anon.

2002-01-01

This article presents the milestones of 2001 concerning nuclear safety in France: 1) the new organization of nuclear safety in France, IPSN (institute of protection and nuclear safety) and OPRI (office for protection against ionizing radiation) have merged into an independent organization: IRSN (institute of radiation protection and nuclear safety); 2) a draft bill has been proposed by the government to impose to nuclear operators new obligations concerning the transfer of information to the public; 3) nuclear safety authorities have drafted a new procedure in order to cope with the demand concerning modification of nuclear fuel management particularly the increase of the burn-up; 4) new evolutions concerning the management of a major nuclear crisis as a consequence of the terrorist attack on New-york and the accident at the AZF plant in Toulouse; 5) a point is made concerning the work of the WENRA association about the harmonization of the nuclear safety policies of its different members. (A.C.)

A origem da Universidade de Paris (I

Directory of Open Access Journals (Sweden)

Ruy Afonso da Costa Nunes

1967-03-01

Foi no princípio do século XIII que a Universidade começou a organizar-se . Em 1200, por um privilégio outorgado por Filipe Augusto, a corporação dos professôres e dos estudantes de Paris passou a reger-se pela jurisdição eclesiástica, furtando-se dessa maneira ao fôro civil. Em 1215, Roberto de Courçon, legado pontifício, conce-deu ao studium parisiense seus primeiros estatutos oficiais . Se tais medidas constituíram o início da organização jurídica da Universidade, foram, por outro lado, o remate de um lento processo de formação . Mas, como decorreu êsse movimento germinativo da Universidade de Paris? Que condições o prepararam e que fatôres contri-buíram para sua gênese e desenvolvimento?

Efficacy of the anti-VZV (anti-HSV3 vaccine in HSV1 and HSV2 recurrent herpes simplex disease: a prospective study

Directory of Open Access Journals (Sweden)

Le Goaster J

2012-07-01

Full Text Available Jacqueline Le Goaster,1 Sylvie Gonzalo,2 Patrice Bourée,1 Frederic Tangy,3 Anne-Lise Haenni41Department of Tropical Diseases, Centre Hospitalo-Universitaire (CHU, University of Paris XI, Le Kremlin Bicêtre, 2Biomnis Laboratory, Ivry-sur-Seine, 3Retro-Virology, Centre National de Recherche Scientifique (CNRS, Pasteur Institute, Paris; 4Jacques Monod Institute, Centre National de Recherche Scientifique (CNRS, University of Paris VII, Paris, FranceBackground: The aim of this study was to evaluate the possibility of using the anti-varicella zoster virus (anti-VZV, also known as anti-HSV3 vaccine against orobuccal herpes simplex virus type 1 (HSV1 and genital herpes simplex virus type 2 (HSV2. This was suggested by study of the phylogenetic tree of members of the herpes virus family, which showed a close relationship between VZV (HSV3 and the HSV1 and HSV2 herpes viruses.Methods: The present prospective study was conducted from January 2005 through January 2011. Twenty-four patients afflicted with HSV1 and HSV2 herpes recurrences over a period of years, numbering 6–8 and more recurrences per year, agreed to receive the anti-VZV vaccine. They were compared with 26 nonvaccinated patients presenting with herpes simplex diseases 2–5 times a year. All 50 patients were documented with anti-HSV1, anti-HSV2, and anti-VZV antibody serological testing.Results: From 2005 through 2011, for the 24 anti-VZV vaccinated patients, the average number of herpes relapses decreased to 0, correlated with an increased anti-VZV antibody level and clinical recovery of all patients, whereas no improvement was observed for the 26 nonvaccinated herpes patients.Conclusion: Data for the anti-VZV serological antibody levels tested before and after anti-VZV vaccination showed a significant (P < 0.001 increase among vaccinated patients. This suggests defective anti-VZV immune power in these patients. After 6 years of positive results for anti-VZV vaccine, this is a logical and

JPRS Report, Science & Technology, Europe & Latin America

Science.gov (United States)

1988-04-06

Aumasson Thermophysics Daniel Balageas Electronic Systems Gerard Gamier Optronic Systems Rene Jalin Systems Experimentation Jean-Claude Theodore...April 1988 54 WEST EUROPE physics laboratory at Cit Descartes , in cooperation with the College of France and the Paris-6, Paris-7 and Paris-12

Interobserver reproducibility of the Paris system for reporting urinary cytology

Directory of Open Access Journals (Sweden)

Theresa Long

2017-01-01

Full Text Available Background: The Paris System for Reporting Urinary Cytology represents a significant improvement in classification of urinary specimens. The system acknowledges the difficulty in cytologically diagnosing low-grade urothelial carcinomas and has developed categories to deal with this issue. The system uses six categories: unsatisfactory, negative for high-grade urothelial carcinoma (NHGUC, atypical urothelial cells, suspicious for high-grade urothelial carcinoma, high-grade urothelial carcinoma, other malignancies and a seventh subcategory (low-grade urothelial neoplasm. Methods: Three hundred and fifty-seven urine specimens were independently reviewed by four cytopathologists unaware of the previous diagnoses. Each cytopathologist rendered a diagnosis according to the Paris System categories. Agreement was assessed using absolute agreement and weighted chance-corrected agreement (kappa. Disagreements were classified as low impact and high impact based on the potential impact of a misclassification on clinical management. Results: The average absolute agreement was 65% with an average expected agreement of 44%. The average chance-corrected agreement (kappa was 0.32. Nine hundred and ninety-nine of 1902 comparisons between rater pairs were in agreement, but 12% of comparisons differed by two or more categories for the category NHGUC. Approximately 15% of the disagreements were classified as high clinical impact. Conclusions: Our findings indicated that the scheme recommended by the Paris System shows adequate precision for the category NHGUC, but the other categories demonstrated unacceptable interobserver variability. This low level of diagnostic precision may negatively impact the applicability of the Paris System for widespread clinical application.

Production of heavy water in France; Production d'eau lourde en France

Energy Technology Data Exchange (ETDEWEB)

Roth, E; Stouls, L; Dirian, G; Lazard, B; Nief, G [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

1958-07-01

Four processes which can be employed on there own or in combination with others, are at present being studied and tried out in France, 1) Process of exchange between H{sub 2}S and H{sub 2}O. A certain amount of laboratory research has been carried out. Also a study of corrosion and operation has been carried out in pilot plants at the same time as the process investigation. 2) Process involving the catalytic exchange H{sub 2}-H{sub 2}O. Studies of liquid phase catalysts are being carried out. 3) The liquid hydrogen distillation process. It has been necessary to resolve numerous theoretical and technological questions. The pilot plant at Toulouse, designed to treat 4000 Nm{sup 3}/h of synthesis gas will soon start production. 4) Process involving the catalytic exchange NH{sub 3}-H{sub 2}. A certain number of investigations have been carried out: the separation coefficient, catalysts, reaction kinetics. The process is promising. The development of a very accurate mass spectrograph has contributed to the success of this work. (author) [French] En France, actuellement, quatre procedes, qui peuvent etre employes seuls ou combines, font l'objet d'etudes et de travaux. 1) Procede d'echange H{sub 2}S-H{sub 2}O. Un certain nombre de recherches de laboratoire ont ete faites. Par ailleurs, des pilotes ont permis d'etudier les problemes de corrosion et de fonctionnement, en meme temps que des etudes de procede ont ete realisees. 2) Procede d'echange catalytique H{sub 2}-H{sub 2}O. Des etudes de catalyseurs en phase liquide se poursuivent. 3) Procede par distillation de H{sub 2} liquide. II y a eu a resoudre de nombreux problemes theoriques ou technologiques. L'usine Pilote de Toulouse, prevue pour traiter 4000 Nm{sup 3}/h de gaz de synthese, doit prochainement entrer dans la phase de production. 4) Procede d'echange catalytique NH{sub 3}-H{sub 2}. Un certain nombre d'etudes sont entreprises: coefficients de separation, catalyseurs, cinetique de reaction. Le procede est

2343-IJBCS-Article-Ngueguim Jules Roger

African Journals Online (AJOL)

hp

4University of Ngaoundéré, Faculty of Science, Department of Biological ... de Paris (MNHN) and the Service d'Action Culturelle of France Embassy in ..... management may allow plantations to ... JRN initiated the research project, did the data ...

Interconnection France-England; Interconnexion France-Angleterre

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-07-01

These documents defines the interconnection France-England rules for the 2000 MW DC submarine cable directly linking the transmission networks of England and Wales and France. Rights to use Interconnector capacity from 1 April 2001 are to be offered through competitive tenders and auctions, full details of which are set out in the Rules. The contract and a guide to the application form are provided. (A.L.B.)

Changes in Plasma Corticosterone and Catecholamine Contents Induced by Low Doses of Deltamethrin in Rats

NARCIS (Netherlands)

Boer, Sietse F. de; Gugten, Jan van der; Slangen, Jef. L.; Hijzen, Theo H.

1988-01-01

The effects of low doses of (S)-α-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylate (Roussel UCLAF, Paris, France), (deltamethrin) upon sympathetic-adrenomedullary and pituitary-adrenocortical activity were investigated in rats by measuring plasma noradrenaline

Pioglitazone could induce remission in major depression: a meta-analysis

Directory of Open Access Journals (Sweden)

Colle R

2016-12-01

Full Text Available Romain Colle,1,* Delphine de Larminat,1,* Samuel Rotenberg,1 Franz Hozer,1 Patrick Hardy,1 Céline Verstuyft,2 Bruno Fève,3,* Emmanuelle Corruble1,* 1Psychiatry Department, Hôpital Bicêtre, INSERM, UMR S1178, University Paris-Sud, Assistance Publique-Hôpitaux de Paris, Le Kremlin Bicêtre, France; 2Molecular Genetic, Pharmacogenetics and Hormonology Department, Hôpital Bicêtre, INSERM UMR_S1184, Centre IMVA, University Paris-Sud, Assistance Publique-Hôpitaux de Paris, Le Kremlin Bicêtre, France; 3Endocrinology Department, INSERM UMR_S938, Hôpital Saint-Antoine, Centre de Recherche Saint-Antoine, Institut Hospitalo-Universitaire ICAN, Sorbonne Universités, Université Pierre et Marie Curie, Assistance Publique des Hôpitaux de Paris, Paris, France *These authors contributed equally to this work Background: Pioglitazone, a selective agonist of the nuclear transcription factor peroxisome proliferator-activated receptor-gamma (PPAR-γ, prescribed for the treatment of type 2 diabetes, could have antidepressant properties. However, its potential to induce remission of major depressive episodes, the optimal clinical target for an antidepressant drug, is a matter of concern. Indeed, only one out of four double-blind randomized controlled trials show higher remission rates with pioglitazone than with control treatments. Hence, the main aim of this study was to perform a meta-analysis of the efficacy of pioglitazone for the treatment of MDE, focusing on remission rates.Methods: Four double-blind randomized controlled trials, comprising 161 patients with an MDE, were included in this meta-analysis. Pioglitazone was studied either alone (one study or as add-on therapy to conventional treatments (antidepressant drugs or lithium salts. It was compared either to placebo (three studies or to metformin (one study. Remission was defined by a Hamilton Depression Rating Scale score <8 after treatment.Results: Pioglitazone could induce higher remission

Energy use and planning in France

International Nuclear Information System (INIS)

Nicolaon, G.A.

1983-01-01

Energy planning in France must compensate for a lack of natural resources and a 77% dependence on imports with conservation, an increased use of domestic sources, and diversified supplies. One problem is a high per-capita energy consumption that, although only half that of the US, has been a financial drain in recent years. Current plans to reduce oil consumption 25% by 1990 and energy dependence to less than 50% include conservation goals set for each sector. Nuclear energy is a cost-effective energy source that is compatible with France's energy goals and is the focus of much energy research. The emphasis on realistic goals and continuity are basic to France's continued success in energy planning. 4 figures, 10 tables

Simulating the formation of carbonaceous aerosol in a European Megacity (Paris) during the Megapoli summer and winter campaigns

NARCIS (Netherlands)

Fountoukis, C.; Megaritis, A.G.; Skyllakou, K.; Charalampidis, P.E.; Denier van der Gon, H.A.C.; Crippa, M.; Prevot, A.S.H.; Fachinger, F.; Wiedensohler, A.; Pilinis, C.; Pandis, S.N.

2016-01-01

We use a three-dimensional regional chemical transport model (PMCAMx) with high grid resolution and high-resolution emissions (4 x 4 km2) over the Paris greater area to simulate the formation of carbonaceous aerosol dur-ing a summer (July 2009) and a winter (January/February 2010) period as part of

Energy in France

International Nuclear Information System (INIS)

Benard, M.

1992-01-01

Geography and clear political leadership have combined to put France in the forefront of both nuclear and hydro-electric generation and energy efficiency so that about 90% of France's electricity is generated by non-fossil fuels. This article explains how and why France has developed its energy mix. (Author)

4TH International Topical Conference on High-Power Electron and Ion-Beam Research and Technology, held in Palaiseau, France, 29 June - 3 July 1981.

Science.gov (United States)

1981-10-09

N. Camarcat (Centre d’Etudes de Valduc ) noted that the French were new in this field and presented the results of the experiments on LIB production...Beam Production on Low Impedance Generators" N. Camarcat et al. C.E.A.-D.A.M.-S.E.C.R. Centre d’Etudes de Valduc , France 7...Acceleration on the Thalie Generator" J. Cortella et al. C.E.A.-D.A.M.-S.E.C.R. Centre d’Etudes de Valduc , France ION PRODUCTION II "The Work on High

Pollution urbaine : la France sous le dôme

OpenAIRE

Laurent, Eloi

2017-01-01

Un an exactement après avoir accueilli la COP21, Paris suffoquait début décembre sous un dôme de pollution, mais aussi Lyon, Villeurbanne, Marseille, Avignon, Rouen ou Grenoble. Airparif, qui a relevé un niveau de particules fines de 146 µg/m3 à Paris en moyenne pour le 1er décembre, précisait dans un communiqué qu’il s’agissait là d’un des pics hivernaux de pollution les plus sévères de ces dix dernières années, les précédents remontant à janvier 2009 et décembre 2007.

The New Microbiology: a conference at the Institut de France.

Science.gov (United States)

Radoshevich, Lilliana; Bierne, Hélène; Ribet, David; Cossart, Pascale

2012-08-01

In May 2012, three European Academies held a conference on the present and future of microbiology. The conference, entitled "The New Microbiology", was a joint effort of the French Académie des sciences, of the German National Academy of Sciences Leopoldina and of the British Royal Society. The organizers - Pascale Cossart and Philippe Sansonetti from the "Académie des sciences", David Holden and Richard Moxon from the "Royal Society", and Jörg Hacker and Jürgen Hesseman from the "Leopoldina Nationale Akademie der Wissenschaften" - wanted to highlight the current renaissance in the field of microbiology mostly due to the advent of technological developments and allowing for single-cell analysis, rapid and inexpensive genome-wide comparisons, sophisticated microscopy and quantitative large-scale studies of RNA regulation and proteomics. The conference took place in the historical Palais de l'Institut de France in Paris with the strong support of Jean-François Bach, Secrétaire Perpétuel of the Académie des sciences. Copyright © 2012 Académie des sciences. Published by Elsevier SAS. All rights reserved.

Visas for Switzerland and France - Time needed to process applications

CERN Multimedia

2012-01-01

Please note that any person required to be in possession of a visa in order to take up functions at CERN must start the application process sufficiently early to allow the visa to be issued in time.   The submission of an incomplete application, local circumstances and an increase in applications before the summer holiday period can all result in considerable variation in the time needed to process your application and issue the visa. You are therefore recommended to submit your visa application at least three months, and not later than 21 days, prior to your departure date. We would also like to remind you that the Swiss Consulate in Paris and the French Consulate in Geneva can issue visas exclusively to people resident within their respective spheres of competence (i.e. those who are holders of a French or Swiss residence permit respectively). You must therefore obtain all visas required for stays longer than three months in France or Switzerland from the visa-issuing authority competent for ...

Karl Marx and the Paris Commune of 1871: Tracing Traditions of Critical Pedagogy

Science.gov (United States)

McGray, Robert

2014-01-01

In 1871, citizens of the war torn arrondissements of Paris, in the face of traumatic political and military turmoil, established a new local form of government. The Paris Commune, as this government became known as in the English world, attracted attention for its alternative political-economic organization. One notable commentator was Karl Marx…

1st International Workshop on Vehicular Ad-hoc Networks for Smart Cities

CERN Document Server

Qayyum, Amir; Saad, Mohamad

2015-01-01

Vehicular communication is a key technology in intelligent transportation systems. For many years now, the academic and industrial research communities have been investigating these communications in order to improve efficiency and safety of future transportation. Vehicular networking offers a wide variety of applications, including safety applications as well as infotainment applications. This book highlights the recent developments in vehicular networking technologies and their interaction with future smart cities in order to promote further research activities and challenges. SAADI BOUDJIT, University of Paris 13, France  HAKIMA CHAOUCHI, Telecom SudParis, France  YACINE GHAMRI, University La Rochelle, France HALABI HASBULLAH, Universiti Teknologi Petronas, Malaysia ANIS LAOUITI, Telecom SudParis, France  SAOUCENE MAHFOUDH, Jeddah, Saudi Arabia  PAUL MUHLETHALER, INRIA, France AMIR QAYYUM, Mohamad Ali Jinnah University, Pakistan NAUFAL SAAD, Universiti Teknologi�...

Air pollution and doctors' house calls for respiratory diseases in the Greater Paris area (2000–3)

Science.gov (United States)

Chardon, Benoit; Lefranc, Agnès; Granados, Denis; Grémy, Isabelle

2007-01-01

This study describes the short‐term relationships between the daily levels of PM10, PM2.5, NO2 and the number of doctors' house calls for asthma, upper respiratory diseases (URD) and lower respiratory diseases (LRD) in Greater Paris for the years 2000–3. Doctors' house calls are a relevant health indicator for the study of short‐term health effects of air pollution. Indeed, it is potentially more sensitive than indicators such as general hospital admissions due to the severity of diseases motivating the call. In this study, time‐series analysis was used. The daily numbers of doctor's house calls were adjusted for time trends, seasonal factors, day of the week, influenza, weather and pollen. Up to 15 days of lag between exposure and health effects was considered using distributed lag models. A total of about 1 760 000 doctors' house calls for all causes occurred during the study period, among which 8027 were for asthma, 52 928 for LRD and 74 845 for URD. No significant increase in risk was found between air pollution and doctors' house calls for asthma. No significant association was found between NO2 and doctors' house calls. An increase of 10 μg/m3 in the mean levels of PM10 and PM2.5 encountered during the 3 previous days was associated with an increase of 3% (0.8% and 5.3%) and 5.9% (2.9% and 9.0%) in the number of doctor's house calls for URD and LRD, respectively. Considering up to 15 days between exposure and health outcomes, effects persist until 4 days after exposure and then decrease progressively. No morbidity displacement was observed. This study shows a significant heath effect of ambient particles (PM2.5 and PM10). When compared to the RRs obtained for mortality or hospital admissions in the same area, the values of the RRs obtained in this study confirm the higher sensibility of doctor's house calls for respiratory diseases as a health indicator. PMID:17182644

Jaromir Krejcar, technique’s apology. Czechoslovak pavilion at the International Exhibition, Paris 1937

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María Pura Moreno Moreno

2018-05-01

Full Text Available L'Exposition Internationale des Arts et Techniques dans les Temps Modernes in Paris (1937 offered, across the construction of their pavilions to each country the opportunity to materialize their technological progress and also to show socio-political factors referred to the art’s integration or aesthetic formalization of their ideologies. In the Czechoslovakian pavilion, made by the architect Jaromir Krejcar, crystallized architectural postulates from the purism, cubism, and new objectivity close to technical aspects driven by the russian constructivism that had been developed during the first decades of the twentieth century in the architecture of the new Czech Republic. Its geographical location, at the crossroads of Europe, had favored the knowledge of avant-garde movements of its two flanks: the Eastern Europe –France, Germany, Austria and Netherlands— on one hand, and the other the Soviet Union. This article will recognize the architectural thought of Krejcar’s generation across the decisions of the pavilion’s project. The characteristics of its emplacement, combined with the moral obligation of showing the high technological level of his country, managed to place it as one of the best examples of that exhibition. Its materialization represent the culmination of previous architectural researches in Czechoslovakia that were truncated from 1939 by the political circumstances.

Surface contamination of nuclear spent fuel shipments. Common Report of the Competent Authorities of France, Germany, Switzerland and the United Kingdom

International Nuclear Information System (INIS)

France; Germany; Switzerland; United Kingdom

1999-01-01

Following the discovery of non-fixed radioactive contamination on spent fuel flasks and associated transport equipment in France, an ad hoc bilateral working group of the competent regulatory authorities was set up by agreement between the German Minister for the Environment, Mrs Angela Merkel, and the French Minister for the Environment, Mrs Dominique Voynet, on 26 May 1998. On 2 June 1998, a constituent meeting of the German, French and now Swiss competent regulatory authorities convened the working group on radioactive contamination in Cologne, Germany. The United Kingdom joined the working group at its second meeting in Paris on 22 June 1998. The working group had the task to ensure a coordinated cooperation of the experts to establish the causes and effects of the contamination incidents and propose appropriate action. This report, agreed at the fifth meeting of the working group in Paris on 24 October 1998, is a compilation of information collected from all four countries, setting out the history of the events, their causes and consequences. The report goes on to describe remedial actions which have already been put in place, those that are being considered, and makes recommendations for future actions. (author)

France energy status for 2011

International Nuclear Information System (INIS)

2012-07-01

2001 was marked by a lifeless global economic context: growth in output, and especially in world trade, slowed sharply. The euro zone was particularly affected. In a tense geopolitical context, especially in the Middle East, international prices of raw materials rose sharply in 2011, in particular oil prices. This affected France's energy bill which, at euro 61.4 billion, increased by almost one-third and accounted for 88% of the country's trade deficit. It thus represents 3.1% of GDP, compared with just 1% in the 1990's. The bill for oil alone is now more than euro 50 billion. The impact could have been even greater if 2011 had not been the warmest year on record since 1900, with an average annual temperature 1.3 deg. C above the reference (1981-2010). As a result, energy needs for heating were much lower than average. The physical trade deficit decreased by 4%, as imports of gas and coal decreased. In terms of consumption, 6.6 million tonnes oil equivalent (Mtoe) were saved. Corrected for climate variations, total primary energy consumption continued its rise in 2011 (+0.8%) after the dip registered in 2009, a consequence of the economic crisis. It thus exceeded 266 Mtoe, but still remains below pre-crisis levels. In spite of lower growth than in the previous year (+ 3.6% against + 4.5% in 2010), consumption of thermal energy from renewable sources and energy recovered from waste showed the strongest increase in 2011. However, at 17.1 Mtoe, this still represents only 6.4% of total primary energy consumption. After two years of reduction, oil showed an upturn (+ 2 %). Primary electricity, also on the rise, consolidated its share of total primary consumption (almost 44%). Conversely, coal dropped by 14 % and its share in primary consumption has been quartered since the 1970's, at less than 4%. The structure of France's primary energy mix has thus stabilised since the mid 2000's. According to European directive indicators, and contrary to the situation in 2010

Key figures on climate France and Worldwide. 2010 Edition

International Nuclear Information System (INIS)

2010-01-01

This document makes a synthesis on the climate in France and in the World. Contents: 1 - Climate Change: The Greenhouse Effect, Humans and the Greenhouse Effect, Stocks and Flows of GHGs: The Example of CO 2 , Increase in Atmospheric GHG Levels, Concentrations and Temperatures, Global Warming, Warming Differentiated by Latitude, Consequences of Global Warming; 2 - Greenhouse Gas Emissions Snapshot of Global GHG Emissions, European Panorama of GHGs, French Panorama of GHGs; 3 - Energy-related CO 2 Emissions in the World: 3.1 Energy-related CO 2 emissions, CO 2 Emissions due to Electricity Production including CHP Plants, CO 2 Emission Factors; 4 - CO 2 Emissions by Sector in Europe and in France: Fuel Combustion: the Largest Emitter of CO 2 , CO 2 Emissions due to Energy Production and Conversion, Transportation-related CO 2 Emissions, Industry-related CO 2 Emissions, CO 2 Emissions in the Other Sectors, CO 2 Emissions excluding Fuel Combustion; 5 - Climate Policies: The Kyoto Protocol, The Tradable Permit Market, Project Mechanisms of the Kyoto Protocol, The European Union's Commitment, European CO 2 Market (EU ETS), Towards a Price Signal for CO 2 Emissions, States Climate Policy: The Case of France, Other Initiatives to Reduce Emissions; 6 - Practical information: CO 2 Key Figures, Glossary of Terms, Useful Links

“Real” Places in Marguerite Duras’s Wartime Paris

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Jennifer Willging

2011-06-01

Full Text Available In the four autobiographical narratives in Marguerite Duras’s La Douleur (1985 The War (1994, over one hundred proper place names appear. While these place names all refer to real places, the relationship between these signifiers and their actual geographical referents is mediated, first by their signifieds—the reader’s mental constructs of the places mentioned—and further by their appearance in a text that necessarily creates its own, non-material world. Yet this essay argues that in this uncharacteristically realist text Duras works hard to create the illusion that the Paris there is in fact Occupied Paris, the real city in which she lived out the experiences recounted in her text. She does this, in large part, by indicating the location of each scene with meticulous precision, thus grounding the stories, quite literally, in a geographically and historically situated reality. While many of these sites are among the best-known, and literal, lieux de mémoire ‘sites of memory’ of the Paris of the Second World War, the mention of more obscure places might appear gratuitous. Yet it is precisely in their gratuity, that such details become essential elements of the forceful effet de réel ‘reality effect’ created in the text.

Misunderstanding in Paris

NARCIS (Netherlands)

Vintges, K.; Hengehold, L.; Bauer, N.

2017-01-01

This chapter discusses the mistaken ways in which Beauvoir's work is interpreted by some of France's leading feminists. It counterposes their reception by arguing that Beauvoir's concept of the free ethical way of life is Hegelian rather than Kantian in character. In The Ethics of Ambiguity she

The climate-problem. Evaluation after the Paris-agreement and the Marrakesh-conference; Das Klimaproblem. Bewertung nach dem Paris-Abkommen und der Marrakesch-Konferenz

Energy Technology Data Exchange (ETDEWEB)

Roth, Eike

2017-05-15

The Paris-Climate-Agreement came into effect on November 4th 2016. Still, the contradiction in this agreement - ambitious goals and (presumably) inadequate commitments - has persisted. Also in the follow-up conference in Marrakesh, this discrepancy remained unresolved. 2017 the countries will meet again. However, since Donald Trump became president-elect of the United States of America, uncertainty about how the largest economy in the world will act in the future has intensified. This amplifies the pressure to clarify the true level of human influence on the climate in a scientifically consistent manner, as a basis for more reliable decisions. This paper tries to contribute to that effort.

Air quality in the mid-21. century for the city of Paris under two climate scenarios; from the regional to local scale

International Nuclear Information System (INIS)

Markakis, K.; Valari, M.; Colette, A.; Sanchez, O.; Perrussel, O.; Honore, C.; Vautard, R.; Klimont, Z.; Rao, S.

2014-01-01

Ozone and PM2.5 concentrations over the city of Paris are modeled with the CHIMERE air-quality model at 4 km x 4 km horizontal resolution for two future emission scenarios. A high-resolution (1 km x 1 km) emission projection until 2020 for the greater Paris region is developed by local experts (AIRPARIF) and is further extended to year 2050 based on regional-scale emission projections developed by the Global Energy Assessment. Model evaluation is performed based on a 10-year control simulation. Ozone is in very good agreement with measurements while PM2.5 is underestimated by 20% over the urban area mainly due to a large wet bias in wintertime precipitation. A significant increase of maximum ozone relative to present-day levels over Paris is modeled under the 'business-as-usual' scenario (+7 ppb) while a more optimistic 'mitigation' scenario leads to a moderate ozone decrease (-3.5 ppb) in year 2050. These results are substantially different to previous regional scale projections where 2050 ozone is found to decrease under both future scenarios. A sensitivity analysis showed that this difference is due to the fact that ozone formation over Paris at the current urban-scale study is driven by volatile organic compound (VOC)-limited chemistry, whereas at the regional-scale ozone formation occurs under NOx-sensitive conditions. This explains why the sharp NOx reductions implemented in the future scenarios have a different effect on ozone projections at different scales. In rural areas, projections at both scales yield similar results showing that the longer timescale processes of emission transport and ozone formation are less sensitive to model resolution. PM2.5 concentrations decrease by 78% and 89% under business-as usual and mitigation scenarios, respectively, compared to the present-day period. The reduction is much more prominent over the urban part of the domain due to the effective reductions of road transport and residential emissions

Air-quality in the mid-21st century for the city of Paris under two climate scenarios; from regional to local scale

Science.gov (United States)

Markakis, K.; Valari, M.; Colette, A.; Sanchez, O.; Perrussel, O.; Honore, C.; Vautard, R.; Klimont, Z.; Rao, S.

2014-01-01

Ozone and PM2.5 concentrations over the city of Paris are modeled with the CHIMERE air-quality model at 4 km × 4 km horizontal resolution for two future emission scenarios. High-resolution (1 km × 1 km) emission projection until 2020 for the greater Paris region is developed by local experts (AIRPARIF) and is further extended to year 2050 based on regional scale emission projections developed by the Global Energy Assessment. Model evaluation is performed based on a 10 yr control simulation. Ozone is in very good agreement with measurements while PM2.5 is underestimated by 20% over the urban area mainly due to a large wet bias in wintertime precipitation. A significant increase of maximum ozone relative to present time levels over Paris is modeled under the "business as usual" scenario (+7 ppb) while a more optimistic mitigation scenario leads to moderate ozone decrease (-3.5 ppb) in year 2050. These results are substantially different to previous regional scale projections where 2050 ozone is found to decrease under both future scenarios. A sensitivity analysis showed that this difference is due to the fact that ozone formation over Paris at the current, urban scale study, is driven by VOC-limited chemistry, whereas at the regional scale ozone formation occurs under NOx-sensitive conditions. This explains why the sharp NOx reductions implemented in the future scenarios have a different effect on ozone projections at different scales. In rural areas projections at both scales yield similar results showing that the longer time-scale processes of emission transport and ozone formation are less sensitive to model resolution. PM2.5 concentrations decrease by 78% and 89% under "business as usual" and "mitigation" scenarios respectively compared to present time period. The reduction is much more prominent over the urban part of the domain due to the effective reductions of road transport and residential emissions resulting in the smoothing of the large urban increment

Nuclear debate in France, some data and commentaries

International Nuclear Information System (INIS)

Sorin, F.

2011-01-01

The gravity of the Fukushima accident has re-activated the controversy about nuclear energy in France. The author reviews the assets of nuclear power (NP) around 8 points: 1) NP is an efficient answer to the growing energy demand of the world, 2) NP does not contribute to climatic change, 3) the winning energy mix is: energy conservation + NP + renewable energies, 4) natural uranium reserves will last at least one or two centuries, 5) concerning radioactive wastes: there is an international consensus for the disposal in deep geological layers of high level radioactive wastes, 6) NP is good business for France: France ranks first as an exporter of nuclear equipment and services, 7) NP assures a very low price for electricity: 0.11 euros/kWh compared to 0.22 euros/kWh in Germany (the price includes the cost of the future dismantlement of the facility), 8) despite the Chernobyl and Fukushima accidents, nuclear industry has the lowest rate of lethal accident than other source of energy like coal, oil, natural gas and hydroelectricity. It is recalled that every year the death toll of fossil energies and hydroelectricity reaches between 12000 and 15000 death. (A.C.)

Implications of possible interpretations of "greenhouse gas balance" in the Paris Agreement

Science.gov (United States)

Millar, R.; Fuglestvedt, J. S.; Rogelj, J.; Allen, M. R.; Boucher, O.; Forster, P.; Kriegler, E.; Shindell, D. T.

2017-12-01

The main goal of the Paris Agreement as stated in its Article 2 is "Holding the increase in the global average temperature to well below 2°C above pre-industrial levels and pursuing efforts to limit the temperature increase to 1.5°C above pre-industrial levels…". Article 4 points to this long-term goal and the need to "… achieve balance between anthropogenic emissions by sources and removals by sinks of greenhouse gases …". The statement on "greenhouse gas balance" is subject to interpretation, and several clarifications are needed in order to make it operational for implementation in climate policies. Here we study possible interpretations from a scientific perspective and analyze their climatic implications. We clarify how the balance referred to in Article 4 of the Paris Agreement applies to anthropogenic sources and anthropogenic sinks and how the implications for individual gases depends strongly on the emission metrics used to relate them. We also show that the way in which balance is interpreted, achieved and maintained influences the anticipated temperature outcome over time. For example, achieving and maintaining net zero CO2-equivalent emissions calculated with the widely used metric Global Warming Potential with a horizon of 100 years (GWP100) - adopted for the implementation of the Kyoto Protocol and in UNFCCC reporting - would result in a peak and decline in global mean temperature. Adopting a different metric, like GWP* (Allen et al., 2016), would result in global mean temperatures remaining approximately constant once net zero CO2-equivalent emissions are achieved and maintained. Policymakers should be aware of these issues and choices and determine which approach is most appropriate in the context of the goals of the Paris Agreement.Reference:Allen, Fuglestvedt, Shine, Reisinger, Pierrehumbert, Forster: New use of global warming potentials to compare cumulative and short-lived climate pollutants. Nature Climate Change (2016). doi:10

Paris, Texas. Saksamaal ja sinu peas / Kairi Prints

Index Scriptorium Estoniae

Prints, Kairi

2010-01-01

6.- 12. oktoobrini Tallinnas ja Tartus toimuval filmifestivalil "Uus Saksa Kino" saab vaadata Wim Wendersi muusikadokumentaale. "Film ja filosoofia" rubriigis koha- ja rahvusespetsiifika eksistentsist tänapäeva filmikunstis ja W. Wendersi filmist "Paris, Texas" (USA 1984)

Seminar on Biogas in France and in Germany: Regulatory framework, potentials and challenges

International Nuclear Information System (INIS)

Abadie, Pierre-Marie; Boettcher, Katharina; Stolpp, Sebastian; Vincent, Eric; Chapron, Thibaut; Schuette, Andreas; Paquin, Laurent; Ingremeau, Claire; Moeller, Kurt; Trommler, Marcus; Denysenko, Velina; Bosso, Valerie

2014-01-01

The French-German office for Renewable energies (OFAEnR) organised a Seminar on biogas in France and Germany. In the framework of this French-German exchange of experience, about 120 participants exchanged views on the legal framework, the characteristics of this industry, and the opportunities and technical challenges of biogas use in both countries. Differences and similarities were noticed in both countries, for instance regarding the use of energy cultures and digestates. This document brings together the available presentations (slides) made during this event: 1 - The French biogas in the perspective of 2020 (Pierre-Marie Abadie); 2 - Biogas Opportunities in Germany - Status January 2014 (Katharina Boettcher); 3 - Biogas market in Germany (Sebastian Stolpp); 4 - Biogas in France and Germany, Current status and development outlooks in France (Eric Vincent); 5 - Biogas use in France and Germany - a comparison (Thibaut Chapron); 6 - Alternatives to the use of maize in biogas plants - Current research results from Germany (Andreas Schuette); 7 - Inter-crops in France: analysis of the potentials (Laurent Paquin); 8 - Digestates management in France, legislative and technical advances (Claire Ingremeau); 9 - The management of digestates in Germany: Fertilizer application and status of the art (Kurt Moeller); 10 - Status quo of Biomethane in Germany - Development, Technology and Costs (Marcus Trommler); 11 - GrDF's views and actions on biogas. Biomethane injection in France: state-of-the-art and first status (Valerie Bosso)

Filaroidosis infection in an immunocompetent adult dog from France

Directory of Open Access Journals (Sweden)

Cervone M.

2018-03-01

Full Text Available A dog from Paris (France was referred with a 2-week history of dry cough, intermittent acute onset of dyspnoea, and acute abdominal pain. A generalised bronchoalveolar infiltrate with a patchy distribution was observed at chest x-rays and computed tomography (CT scans. Negative results were obtained through several faecal examinations for cardiorespiratory nematodes by using the Baermann technique and at two blood analysis with a commercially available test for the detection of A. vasorum antigen (the first one at the first visit and second one at the control visit, one month later. PCR methods for the identification of A. vasorum and C. vulpis were also accomplished. At the control visit, nematode L1s were found during direct microscopic examination of bronchoalveolar lavage fluid (BALF. Thus, a different antigen-based assay for the detection of A. vasorum was performed with a positive result. Moreover, based on morphology, isolated larvae were identified as Filaroides hirthi. The dog was treated with fenbendazole (50 mg/kg per os once daily for two consecutive weeks. After five months, the dog was referred again for the intermittent acute onset of dyspnoea and was found to be still positive for F. hirthi larvae at BALF examination. A 15-day treatment regimen with fenbendazole in combination with three subcutaneous injections of ivermectin (0.4 mg/kg, once every two weeks, was then performed. No larvae were detected at two BALF microscopical examinations performed one month apart. Results from this case report underline the importance of including F. hirthi infections in the differential diagnosis of dog bronchopneumonia.

EdF competing in the European electricity market. Interview with Francois Ailleret, Electricite de France, Paris

International Nuclear Information System (INIS)

Anon.

1996-01-01

The French nuclear power program was pushed through in order to reduce the country's dependence on imported fossil sources of energy. Nuclear power and hydro power have achieved a level of self-sufficiency in the energy sector of more than 50%. It should be emphasized that the French nuclear power program was largely self-financed. Electricite de France (EdF) considers itself well prepared for the European market, provided the creation of the single market implies that electricity rates are taken as a yardstick of competitiveness. Negotiations about a European directive on deregulating the electricity market were for the government to hold. EdF pleaded in favor of preserving for each country a certain leeway for shaping its own policy. The road to deregulation was to be opened, but the specific situation of each country was to be taken electricity to be passed through imposes narrow constraints upon an expansion of exchanges of electricity, and public acceptance is not very likely to be achieved for the construction of new international high voltage transmission lines. (orig.) [de

Formulation and cytotoxicity evaluation of new self-emulsifying multiple W/O/W nanoemulsions

Directory of Open Access Journals (Sweden)

Sigward E

2013-02-01

Full Text Available Estelle Sigward,1 Nathalie Mignet,1 Patrice Rat,2 Mélody Dutot,2 Saleh Muhamed,1 Jean-Michel Guigner,3 Daniel Scherman,1 Denis Brossard,1 Sylvie Crauste-Manciet11Chemical, Genetic and Imaging Pharmacology Laboratory; INSERM U1022, CNRS UMR8151, Chimie ParisTech, Faculty of Pharmacy, Paris Descartes University, Sorbone Paris Cité, Paris, France; 2Chemistry-Cellular and Analytical Toxicology Laboratory (C-TAC, Faculty of Pharmacy, Paris Descartes University, Sorbone Paris Cité, Paris, France; 3Institut de Minéralogie et de Physique des Milieux Condensés IMPMC -IRD-CNRS UMR 7590, Université Paris Pierre et Marie Curie, Paris, FranceAbstract: Three multiple water-in-oil-in-water (W/O/W nanoemulsions have been designed for potential inclusion of either lipophilic or hydrophilic drugs using a two-step emulsification process exclusively based on low-energy self-emulsification. The W/O primary emulsion was constituted by a blend of oil (medium chain triglyceride, a mixture (7:3 of two surfactants, and a 10% water phase. The surfactants were a mixture of Polysorbate-85/Labrasol®, Polysorbate-85/ Cremophor® EL or glycerol/Polysorbate-85. The final W/O/W nanoemulsions were obtained by the addition of water, with a weight ratio nanoemulsion/water of 1:2. The multiple emulsion stability was found to increase from 24 hours to 2 and 6 months with Labrasol, glycerol, and Cremophor, respectively. Cytotoxicity was found for formulations including Labrasol and Cremophor EL. The concentration of emulsion inhibiting 50% cell viability (IC50 was determined using the alamarBlue® test, giving after 24 hours of incubation, IC50 = 10.2 mg/mL for the Labrasol formulation and IC50 = 11.8 mg/mL for the Cremophor EL formulation. Corresponding calculated IC50 values for surfactants were 0.51 mg/mL for Labrasol and 0.59 mg/mL for Cremophor EL. In both cases, cytotoxicity was due to an apoptotic mechanism, evidenced by chromatin condensation and P2X7 cell death

Fulltext PDF

Indian Academy of Sciences (India)

Bellissard Jean, Georgia Inst. of Technology, Atlanta, USA. Bernard Guilhem, LAPTh, Annecy-le-Vieux, France. Blanchard Philippe, Univ. Bielefeld, Germany. Boudjema Fawzi, LAPTh, Annecy-le-Vieux, France. Brezin Edouard, LPT, Ecole Normale Supérieure, Paris, France. Bros Jacques, DSM/IPhT, CEA Saclay, France.

Algumas raízes do anti-semitismo no Brasil ou um outro olhar sobre Paris Anti-semitic roots in Brazil or a different view of Paris

Directory of Open Access Journals (Sweden)

Eva Alterman Blay

2001-05-01

Full Text Available A construção da cultura passa por múltiplas influências culturais. A dinâmica cultural desmente pretensas posições etnocêntricas. Ao longo do tempo a história brasileira se viu vinculada a vários sistemas socioculturais e, nos dois últimos séculos, às influências ibérica, africana e indígena houve intensa incorporação da cultura francesa e anglo-saxônica que somadas, moldaram, em grande parte, nossos corações e mentes. Neste trabalho se focaliza a influência da cultura e do catolicismo conservador francês na formação do anti-semitismo brasileiro. A partir da análise da iconografia religiosa se observará uma das fontes da construção da diabolização do judeu no imaginário popular e culto. A construção da exclusão social dos judeus franceses e sua deportação para campos de concentração será observada através de um roteiro pelo Marais, o bairro judaico de Paris. A arquitetura concentracionista de Corbusier completa o quadro da exclusão social. Todos estes elementos, reunidos, permitem entender, em parte, como foi sendo construída a imagem do judeu imigrante no Brasil expressa por vários autores.The construction of culture undergoes a number of cultural influences. Cultural dynamics disavows alleged ethnocentric positions. From the beginning, Brazilian history has been linked to various socio-cultural systems. In the last two centuries, an intense incorporation of French and Anglo-Saxon cultures has been added to the Iberian, African and Native influences. Together, these have molded, to a large extent, our hearts and minds. This paper focuses on the influence of French culture and French conservative Catholicism in the constitution of Brazilian anti-semitism. The analisys of religious iconography reveals one of the sources of the satanization of the Jews in popular and elite imagination. The development of the social exclusion of the French Jews and their deportation to the concentration camps is analysed

USA Withdrawal from Paris Agreement – What Next?

Directory of Open Access Journals (Sweden)

Sergey Chestnoy

2017-12-01

Full Text Available In June 2017, President Trump announced the USA’s withdrawal from the Paris Climate Accord, which had been ratified for less than a year, thanks in large part to the USA. That drastic shift followed the change in residency at the White House. Withdrawing from the Paris Accord presents an interesting topic for analysis. There’s the practical side of the withdrawal procedure as set out in Article 28 of the agreement, not to mention the consequences of US non-participation in addressing international climate issues. There are other international forums (Such as G8 and G20, which also have an interest in climate related topics. The Article analyses the U.S. position in negotiations and its commitments assumed the moment the United Nations Framework Convention on Climate Change (UNFCCC came into effect until now: the reduction of greenhouse gas emissions, financial aid and reporting. It also provides general analysis of national legal obligations under the Paris Accord, ratification of that agreement in general and in particularly another that took place in the USA, it focuses on the specifics of withdrawal. The specified three-year period from the Agreement becoming active, after which any party may withdraw from it (2019, is a noteworthy detail. It is well-known that the Paris Agreement provides a framework that does not impose individual national commitments or a commitment to a compliance system. In essence, and from a legal point of view, it is nonbinding. This was what allowed the USA to accept the terms of the accord relatively quickly and to use the simplified procedure, which by-passed Congress. In the opinion of the authors, President Trump’s resolution to withdraw should, possibly, be considered as a simple continuation of his election discourse and the fulfilment of a campaign promise. Additionally, President Trump’s declared intent to review the Paris Accord has legal grounds on which to launch further international negotiations

Pilot Phase II study of mazindol in children with attention deficit/hyperactivity disorder

Directory of Open Access Journals (Sweden)

Konofal E

2014-12-01

Full Text Available Eric Konofal,1,2 Wei Zhao,3–5 Cédric Laouénan,5–7 Michel Lecendreux,1,2 Florentia Kaguelidou,3–5 Lila Benadjaoud,4 France Mentré,5–7 Evelyne Jacqz-Aigrain3–51Pediatric Sleep Disorders Center, 2Child and Adolescent Psychiatric Department, 3Department of Pediatric Pharmacology and Pharmacogenetics, Hôpital Robert Debré, Assistance Publique – Hôpitaux de Paris (APHP, 4Clinical Investigation Center, Institut National de la Santé et de la Recherche Médicale (INSERM, 5Université Paris Diderot, Sorbonne Paris Cité, Paris, 6INSERM, Infection, Antimicrobiens, Modélisation, Evolution (IAME, UMR1137, Paris, 7Department of Biostatistiques, Hôpital Bichat, APHP, Paris, FranceObjective: Mazindol has been proposed as a potential treatment of children with attention deficit/hyperactivity disorder (ADHD. The purpose of this pilot study was to assess its pharmacokinetics, short-term efficacy, and safety.Subjects and methods: A total of 24 children (aged 9–12 years with ADHD (according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, text-revision criteria received a daily dose of 1 mg for 7 days and were followed for 3 additional weeks. Pharmacokinetic samples were collected after the first administration. ADHD symptoms were assessed using the ADHD Rating Scale (RS-IV, Conners’ Parent Rating Scale – Revised: Long (CPRS-R:L at screening, baseline, and the end of the study. The Clinical Global Impression – Severity (CGI-S scale was assessed at baseline, and the CGI – Improvement (CGI-I scale was assessed at subsequent visits.Results: Twenty-one subjects (aged 10±1 years were analyzed. Pharmacokinetic data were described by a one-compartment model with first-order absorption, elimination, and lag time. The typical apparent clearance and apparent volume of distribution were 27.9 L/h and 234 L, and increased with fat-free mass and age, respectively. The mean change in score in ADHD RS-IV after 1 week of

France's nuclear power programme; Le programme nucleaire francais

Energy Technology Data Exchange (ETDEWEB)

Cabanius, J [Electricite de France (EDF), 75 - Paris (France); Horowitz, J [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

1964-07-01

The prospects of development of France's consumption of electricity will widen the deficit of her national energy resources. Nuclear power stations should enable this deficit to be reduced, provided a certain number of uncertainties prevailing today are resolved. The first programme, put forward by Messrs. AILLERET and TARANGER at the 1955 Geneva Conference aimed at commissioning 850 MWe by 1965; the programme was devoted to developing the natural uranium graphite-gas sequence and reaches its completion with the construction of EDF 3, the world's first unit capable of 500 MWe. Before changing over from the prototype stage to their duplication, Electricite De France decided, in agreement with the Commissariat A L'energie Atomique to build EDF 4, which, while reproducing EDF 3's reactor, together with the referring equipment, the entire control equipment and various other systems, pioneers an important innovation by incorporating the heat exchangers and fans inside the prestressed concrete pressure vessel housing the core. At the same time, studies are being carried on on the same type of reactor enabling possible use of a new annular-shaped fuel element, whose use would considerably improve the performance of EDF 5, to be envisaged. On the heavy water side, the construction of EL 4 at Brennilis jointly by the Commissariat A L'energie Atomique and Electricite De France is continuing. Design work on a 500 MWe reactor of this type has already started. As regards pressurized water reactors, the Chooz power station is built jointly by Electricite De France and Belgian Utilities. Finally, the Commissariat A L'energie Atomique is continuing the construction of the 'Rapsodie' rapid neutron reactor at Cadarache, together with studies on a larger power reactor. It may thus be seen that the technical and economic knowledge gained on these various types of reactor mean that an equipment program may be contemplated which will endow nuclear power stations with a place of ever

Conference on offshore wind power in France and Germany

International Nuclear Information System (INIS)

Meyer, Ronny; Furois, Timothee; Nolte, Nico; Lanoe, Frederic; Lehmann-Matthaei, Bjoern; Ifflaender, Andree; Courcambeck, Alexandre; Giese, Norbert; Kavafyan, Philippe; Bjaert, Niels; Wagner, Andreas; Guillet, Jerome

2014-01-01

The French-German office for Renewable energies (OFAEnR) organised a conference on offshore wind power in France and Germany. In the framework of this French-German exchange of experience, about 120 participants exchanged views on the planning and authorisation procedures implemented in both countries and on the installation, connection to the grid and maintenance of offshore wind turbines. environmental impacts and usage conflicts linked with offshore wind farms exploitation were addressed as well. This document brings together the available presentations (slides) made during this event: 1 - Update: Offshore Wind In Germany (Ronny Meyer); 2 - Offshore wind development in France (Timothee Furois); 3 - The Licensing Procedure for Offshore Wind Farms in the German EEZ (Nico Nolte); 4 - Spatial Planning and Permitting in France: What leverage for more efficiency? (Frederic Lanoe); 5 - Results of 10 years environmental research on FINO-platforms (Bjoern Lehmann-Matthaei); 6 - Offshore Grid Connection - Status Quo and Overview (Andree Ifflaender); 7 - Grid connection of Offshore Wind in France: Situation, perspectives and recommendations (Alexandre Courcambeck); 8 - Controlling risks and warranting safety: Best practices for the installation, exploitation and maintenance of offshore wind turbines (Norbert Giese); 9 - Offshore wind Bremerhaven experience: An essential asset for the development of a complete Wind Offshore industry in France (Philippe Kavafyan); 10 - Standardizing and Cost Reduction -Lessons Learned from London Array (Niels Bjaert); 11 - Offshore Wind energy in Germany: System Benefits and Cost Reduction Potentials. Presentation of study results from prognos/fichtner and Fraunhofer-IWeS (Andreas Wagner); 12 - Offshore Wind energy financing - opportunities and risks (Jerome Guillet)

What does the Paris Agreement mean for adaptation?

NARCIS (Netherlands)

Lesnikowski, Alexandra; Ford, James; Biesbroek, Robbert; Berrang-Ford, Lea; Maillet, Michelle; Araos, Malcolm; Austin, Stephanie E.

2017-01-01

The Paris Agreement takes a significant step forward in strengthening the adaptation pillar of global climate policy. By widening the normative framing around adaptation, calling for stronger adaptation commitments from states, being explicit about the multilevel nature of adaptation governance, and

Global mean sea-level rise in a world agreed upon in Paris

Science.gov (United States)

Bittermann, Klaus; Rahmstorf, Stefan; Kopp, Robert E.; Kemp, Andrew C.

2017-12-01

Although the 2015 Paris Agreement seeks to hold global average temperature to ‘well below 2 °C above pre-industrial levels and to pursue efforts to limit the temperature increase to 1.5 °C above pre-industrial levels’, projections of global mean sea-level (GMSL) rise commonly focus on scenarios in which there is a high probability that warming exceeds 1.5 °C. Using a semi-empirical model, we project GMSL changes between now and 2150 CE under a suite of temperature scenarios that satisfy the Paris Agreement temperature targets. The projected magnitude and rate of GMSL rise varies among these low emissions scenarios. Stabilizing temperature at 1.5 °C instead of 2 °C above preindustrial reduces GMSL in 2150 CE by 17 cm (90% credible interval: 14-21 cm) and reduces peak rates of rise by 1.9 mm yr-1 (90% credible interval: 1.4-2.6 mm yr-1). Delaying the year of peak temperature has little long-term influence on GMSL, but does reduce the maximum rate of rise. Stabilizing at 2 °C in 2080 CE rather than 2030 CE reduces the peak rate by 2.7 mm yr-1 (90% credible interval: 2.0-4.0 mm yr-1).

climate change and lake water resourcesin sub-saharan africa: case ...

African Journals Online (AJOL)

user

STUDY OF LAKE CHAD AND LAKE VICTORIA ... contribution to agriculture and socio-economic development of the region were ... many developing countries, current levels in water use .... 2050 and will become increasingly urban by implication. ... 4.1 Justification of Selected Case Studies ..... Orstom, Paris France. 1996.

Contribution of mesoscale processes to nutrient budgets in the Arabian Sea

Digital Repository Service at National Institute of Oceanography (India)

Resplandy, L; Levy, M.; Madec, G.; Pous, S.; Aumont, O.; DileepKumar, M.

Contribution of mesoscale processes to nutrient1 budgets in the Arabian Sea2 L. Resplandy, 1 M. L´evy, 1 G. Madec, 1,2 S. Pous, 1 O. Aumont, 3 D. Kumar 4 L. Resplandy, LOCEAN, UPMC, BC100, 4 place Jussieu, F-75252 Paris cedex 05, France. (lrlod... is constant and set to 122/16 [Takahashi et al., 1985]. To ensure positive values, biogeo-141 chemical tracers are advected with the positive Monotone Upstream-centered Schemes for142 Conservation Laws [Van Leer, 1979; L´evy et al., 2001] and dissipated along...

U.S. withdrawal from the Paris Agreement: Reasons, impacts, and China's response

OpenAIRE

Hai-Bin Zhang; Han-Cheng Dai; Hua-Xia Lai; Wen-Tao Wang

2017-01-01

Applying qualitative and quantitative methods, this article explains the driving forces behind U.S. President Donald Trump's decision to withdraw from the Paris Agreement, assesses the impacts of this withdrawal on the compliance prospects of the agreement, and proposes how China should respond. The withdrawal undercuts the foundation of global climate governance and upsets the process of climate cooperation, and the impacts are manifold. The withdrawal undermines the universality of the Pari...

Quantitative determination of carbonaceous particle mixing state in Paris using single particle mass spectrometer and aerosol mass spectrometer measurements

Science.gov (United States)

Healy, R. M.; Sciare, J.; Poulain, L.; Crippa, M.; Wiedensohler, A.; Prévôt, A. S. H.; Baltensperger, U.; Sarda-Estève, R.; McGuire, M. L.; Jeong, C.-H.; McGillicuddy, E.; O'Connor, I. P.; Sodeau, J. R.; Evans, G. J.; Wenger, J. C.

2013-04-01

Single particle mixing state information can be a powerful tool for assessing the relative impact of local and regional sources of ambient particulate matter in urban environments. However, quantitative mixing state data are challenging to obtain using single particle mass spectrometers. In this study, the quantitative chemical composition of carbonaceous single particles has been estimated using an aerosol time-of-flight mass spectrometer (ATOFMS) as part of the MEGAPOLI 2010 winter campaign in Paris, France. Relative peak areas of marker ions for elemental carbon (EC), organic aerosol (OA), ammonium, nitrate, sulphate and potassium were compared with concurrent measurements from an Aerodyne high resolution time-of-flight aerosol mass spectrometer (HR-ToF-AMS), a thermal/optical OCEC analyser and a particle into liquid sampler coupled with ion chromatography (PILS-IC). ATOFMS-derived mass concentrations reproduced the variability of these species well (R2 = 0.67-0.78), and ten discrete mixing states for carbonaceous particles were identified and quantified. Potassium content was used to identify particles associated with biomass combustion. The chemical mixing state of HR-ToF-AMS organic aerosol factors, resolved using positive matrix factorization, was also investigated through comparison with the ATOFMS dataset. The results indicate that hydrocarbon-like OA (HOA) detected in Paris is associated with two EC-rich mixing states which differ in their relative sulphate content, while fresh biomass burning OA (BBOA) is associated with two mixing states which differ significantly in their OA/EC ratios. Aged biomass burning OA (OOA2-BBOA) was found to be significantly internally mixed with nitrate, while secondary, oxidized OA (OOA) was associated with five particle mixing states, each exhibiting different relative secondary inorganic ion content. Externally mixed secondary organic aerosol was not observed. These findings demonstrate the heterogeneity of primary and

Quantitative determination of carbonaceous particle mixing state in Paris using single-particle mass spectrometer and aerosol mass spectrometer measurements

Directory of Open Access Journals (Sweden)

R. M. Healy

2013-09-01

Full Text Available Single-particle mixing state information can be a powerful tool for assessing the relative impact of local and regional sources of ambient particulate matter in urban environments. However, quantitative mixing state data are challenging to obtain using single-particle mass spectrometers. In this study, the quantitative chemical composition of carbonaceous single particles has been determined using an aerosol time-of-flight mass spectrometer (ATOFMS as part of the MEGAPOLI 2010 winter campaign in Paris, France. Relative peak areas of marker ions for elemental carbon (EC, organic aerosol (OA, ammonium, nitrate, sulfate and potassium were compared with concurrent measurements from an Aerodyne high-resolution time-of-flight aerosol mass spectrometer (HR-ToF-AMS, a thermal–optical OCEC analyser and a particle into liquid sampler coupled with ion chromatography (PILS-IC. ATOFMS-derived estimated mass concentrations reproduced the variability of these species well (R2 = 0.67–0.78, and 10 discrete mixing states for carbonaceous particles were identified and quantified. The chemical mixing state of HR-ToF-AMS organic aerosol factors, resolved using positive matrix factorisation, was also investigated through comparison with the ATOFMS dataset. The results indicate that hydrocarbon-like OA (HOA detected in Paris is associated with two EC-rich mixing states which differ in their relative sulfate content, while fresh biomass burning OA (BBOA is associated with two mixing states which differ significantly in their OA / EC ratios. Aged biomass burning OA (OOA2-BBOA was found to be significantly internally mixed with nitrate, while secondary, oxidised OA (OOA was associated with five particle mixing states, each exhibiting different relative secondary inorganic ion content. Externally mixed secondary organic aerosol was not observed. These findings demonstrate the range of primary and secondary organic aerosol mixing states in Paris. Examination of the

Quantitative determination of carbonaceous particle mixing state in Paris using single-particle mass spectrometer and aerosol mass spectrometer measurements

Science.gov (United States)

Healy, R. M.; Sciare, J.; Poulain, L.; Crippa, M.; Wiedensohler, A.; Prévôt, A. S. H.; Baltensperger, U.; Sarda-Estève, R.; McGuire, M. L.; Jeong, C.-H.; McGillicuddy, E.; O'Connor, I. P.; Sodeau, J. R.; Evans, G. J.; Wenger, J. C.

2013-09-01

Single-particle mixing state information can be a powerful tool for assessing the relative impact of local and regional sources of ambient particulate matter in urban environments. However, quantitative mixing state data are challenging to obtain using single-particle mass spectrometers. In this study, the quantitative chemical composition of carbonaceous single particles has been determined using an aerosol time-of-flight mass spectrometer (ATOFMS) as part of the MEGAPOLI 2010 winter campaign in Paris, France. Relative peak areas of marker ions for elemental carbon (EC), organic aerosol (OA), ammonium, nitrate, sulfate and potassium were compared with concurrent measurements from an Aerodyne high-resolution time-of-flight aerosol mass spectrometer (HR-ToF-AMS), a thermal-optical OCEC analyser and a particle into liquid sampler coupled with ion chromatography (PILS-IC). ATOFMS-derived estimated mass concentrations reproduced the variability of these species well (R2 = 0.67-0.78), and 10 discrete mixing states for carbonaceous particles were identified and quantified. The chemical mixing state of HR-ToF-AMS organic aerosol factors, resolved using positive matrix factorisation, was also investigated through comparison with the ATOFMS dataset. The results indicate that hydrocarbon-like OA (HOA) detected in Paris is associated with two EC-rich mixing states which differ in their relative sulfate content, while fresh biomass burning OA (BBOA) is associated with two mixing states which differ significantly in their OA / EC ratios. Aged biomass burning OA (OOA2-BBOA) was found to be significantly internally mixed with nitrate, while secondary, oxidised OA (OOA) was associated with five particle mixing states, each exhibiting different relative secondary inorganic ion content. Externally mixed secondary organic aerosol was not observed. These findings demonstrate the range of primary and secondary organic aerosol mixing states in Paris. Examination of the temporal

Assessment of indoor environment in Paris child day care centers.

Science.gov (United States)

Roda, Célina; Barral, Sophie; Ravelomanantsoa, Hanitriniala; Dusséaux, Murielle; Tribout, Martin; Le Moullec, Yvon; Momas, Isabelle

2011-11-01

Children are sensitive to indoor environmental pollution. Up until now there has been a lack of data on air quality in child day care centers. The aim of this study is to document the indoor environment quality of Paris child day care centers by repeated measurements, and to compare pollutant levels in child day care centers with levels in Paris dwellings. We selected 28 child day care centers frequented by a random sample of babies who participated in the PARIS birth cohort environmental investigation, and visited the child day care centers for one week twice in one year. Biological contaminants assessed were fungi, endotoxin, dust mite allergens, and chemical pollutants: aldehydes, volatile organic compounds and nitrogen dioxide (NO2). Relative humidity, temperature, and carbon dioxide levels were measured simultaneously. A standardized questionnaire was used to gather information about the buildings and their inhabitants. Airborne endotoxin levels in child day care centers were higher than those found in Paris dwellings. Dust mite allergens in child day care centers were below the threshold level for sensitization in the majority of samples, and in common with dwelling samples. Penicillium and Cladosporium were the most commonly identified genera fungi. The child day care center indoor/outdoor ratio for most chemical pollutants was above unity except for NO2, the levels for NO2 being significantly higher than those measured in homes. Chemical and biological contamination in child day care centers appears to be low, apart from endotoxin and NO2. Failure to take child exposure in child day care centers into account could result in an overestimation of children's exposure to other pollutants. Copyright © 2011 Elsevier Inc. All rights reserved.

France at CERN

CERN Multimedia

GS Department

2010-01-01

Industrial Exhibition Administration Building Bldg 61 Tuesday 8 June: 9 a.m. – 5.30 p.m. Wednesday 9 June: 9 a.m. – 4 p.m. “FRANCE AT CERN” – INDUSTRIAL EXHIBITION Thirty-six French companies are presenting their latest technological advances during the industrial exhibition "France at CERN", featuring products and technologies specifically related to the activities of the CERN facility. Presenting their know-how in electric vehicles, PSA - PEUGEOT/CITROEN are sponsoring the event. Seminars will be hold in the Main Building’s conference rooms: R&D innovation strategy in Pôle Nucléaire Bourgogne (08/06/2010 – 13h) MU by Peugeot (08/06/2010 – 14h) Citroën (08/06/2010 – 15h) « Elément 14 » : a unique design engineer community for sharing Electronic Engineering Solutions (09/06/2010 – 11h) Individual B2B meetin...

Revision of the Paris and Brussels Conventions of Nuclear Liability

International Nuclear Information System (INIS)

Reyners, P.

2002-01-01

The Contracting Parties to the 1960 Paris Convention on Third Party Liability in the Field of Nuclear Energy and to the 1963 Brussels Convention Supplementary to the Paris Convention, have concluded this Spring four years of negotiation on the revision of these instruments. This exercise was itself started as a logical consequence of the adoption in 1997 of a revised Vienna Convention on Civil Liability for Nuclear Damage and of a Convention on Supplementary Compensation for Nuclear Damage. The Contracting Parties have concluded that the existing regime established by these Conventions remains viable and sound but that it also warrants improvements to ensure that greater financial security will be available to compensate a potentially larger number of victims in respect of a broader range of nuclear damage. A number of more technical amendments have also been agreed, in particular to ensure compatibility with other existing Conventions in this field. When the revised Paris and Brussels Conventions come into force, the total amount of funds available for compensation, provided by the liable nuclear operator and by the States concerned, will be 1.5 billion euros. (author)

Business process management : 3rd international conference, BPM 2005, Nancy, France, September 5-8, 2005 : proceedings

NARCIS (Netherlands)

Aalst, van der W.M.P.; Benatallah, B.; Casati, F.; Curbera, F.

2005-01-01

This volume contains the proceedings of the 3rd International Conference on Business Process Management (BPM 2005), organized by LORIA in Nancy, France, September 5–8, 2005. This year, BPM included several innovations with respect to previous editions, most notably the addition of an industrial

Proceedings of the second workshop of LHC Computing Grid, LCG-France

International Nuclear Information System (INIS)

Chollet, Frederique; Hernandez, Fabio; Malek, Fairouz; Gaelle, Shifrin

2007-03-01

The second LCG-France Workshop was held in Clermont-Ferrand on 14-15 March 2007. These sessions organized by IN2P3 and DAPNIA were attended by around 70 participants working with the Computing Grid of LHC in France. The workshop was a opportunity of exchanges of information between the French and foreign site representatives on one side and delegates of experiments on the other side. The event allowed enlightening the place of LHC Computing Task within the frame of W-LCG world project, the undergoing actions and the prospects in 2007 and beyond. The following communications were presented: 1. The current status of the LHC computation in France; 2.The LHC Grid infrastructure in France and associated resources; 3.Commissioning of Tier 1; 4.The sites of Tier-2s and Tier-3s; 5.Computing in ALICE experiment; 6.Computing in ATLAS experiment; 7.Computing in the CMS experiments; 8.Computing in the LHCb experiments; 9.Management and operation of computing grids; 10.'The VOs talk to sites'; 11.Peculiarities of ATLAS; 12.Peculiarities of CMS and ALICE; 13.Peculiarities of LHCb; 14.'The sites talk to VOs'; 15. Worldwide operation of Grid; 16.Following-up the Grid jobs; 17.Surveillance and managing the failures; 18. Job scheduling and tuning; 19.Managing the site infrastructure; 20.LCG-France communications; 21.Managing the Grid data; 22.Pointing the net infrastructure and site storage. 23.ALICE bulk transfers; 24.ATLAS bulk transfers; 25.CMS bulk transfers; 26. LHCb bulk transfers; 27.Access to LHCb data; 28.Access to CMS data; 29.Access to ATLAS data; 30.Access to ALICE data; 31.Data analysis centers; 32.D0 Analysis Farm; 33.Some CMS grid analyses; 34.PROOF; 35.Distributed analysis using GANGA; 36.T2 set-up for end-users. In their concluding remarks Fairouz Malek and Dominique Pallin stressed that the current workshop was more close to users while the tasks for tightening the links between the sites and the experiments were definitely achieved. The IN2P3 leadership expressed

Walter Benjamin e Paris: individualidade e trabalho intelectual

Directory of Open Access Journals (Sweden)

Renato Ortiz

2000-05-01

Full Text Available Este artigo é uma leitura do texto de Walter Benjamin Paris capital do século XIX. A partir do conjunto de anotações que Benjamin faz de diversos livros consultados, principalmente durante sua pesquisa na Bibliothèque Nationale, o autor pretende trabalhar a noção de indivíduo vinculando-a a dois temas. Primeiro, a emergência do flâneur como tradução do espírito de mobilidade que se inaugura com a modernidade. Para isso a discussão sobre a noção de espaço, particularmente no que diz respeito a cidade de Paris, é importante. O flâneur surge assim como um indivíduo desenraizado que se locomove através do espaço urbano remodelado. Segundo, uma aproximação entre o ato da flânerie e o trabalho intelectual. Considerando a flânerie como uma atividade intelectual o autor mostra como os temas do distanciamento e da construção do objeto são relevantes tanto para o flâneur-detetive quanto para a reflexão nas ciências sociais.This paper is an interpretation of Walter Benjamins Paris, Capital of the 19th Century. Based on the notes Benjamin made on several books he read, mainly during his research at the Bibliotèque Nationale, the author discusses the notion of the individual linking it to two themes. First, to the emergence of the flâneur as a translation of the spirit of mobility which starts with modernity. The discussion on the notion of space, especially where it concerns Paris, is essential for this analysis. The flâneur is seen as an uprooted individual who moves around the remodelled urban space. Second, to the proximity between the act of flânerie and that of intellectual work. Taking flânerie to be intellectual activity, the author shows how the themes of the distancing and the construction of the object are relevant, both to the detective-flâneur and to the reflection in social sciences.

Future health impact assessment of air pollution at the global, European and Ile-de-France scales: the Air Pollution Climate Health Impact Assessment (A-C HIA) project

International Nuclear Information System (INIS)

Likhvar, Victoria; Hauglustaine, Didier; Kinney, Patrick; Colette, Augustin; Valari, Myrto; Markakis, Konstandinos; Pascal, Mathilde; Medina, Sylvia

2016-01-01

Ozone and fine particles are current risk factors for premature death all over the globe. In coming decades, substantial improvements in public health may be achieved by reducing air pollution. The overall objective of the A-C HIA project (2011-2014) was to apply state of the art climate, air quality, and health modelling tools to assess future health impacts of O 3 and PM2.5 under different scenarios of emissions for the period 2030-2050. A-C HIA created an interdisciplinary team to study the impacts of climate change on health through air quality changes, and to establish longer-term collaborations between communities. This question has been explored at three spatial scales: global, regional (Europe), and urban (ile-de-France). We f ind that 1.5 millions of cardio-vascular deaths could be delayed each year in 2030 compared to 2010. In Europe, air-pollution-related mortality should decrease in 2030 compared to 2010. At the finer scale (ile-de-France) we found that the respiratory mortality should increase over the highly populated area of Paris. In the coming years, substantial benefits to public health could be achieved through coordinated strategies to reduce emissions of greenhouse gases and improving air quality. (authors)

EDF - Electricite de France. Results 1997. 1997: The enterprise prepares for competition; EDF - Electricite de France. Resultats 1997. 1997: L'entreprise se prepare a la concurrence

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-07-01

In 1997 the energy production of the French Electricity Company EDF (Electricite de France) reached the value of 457.7 billion kWh, of which 82% is nuclear, 14% hydraulic and 4% classical thermal power. The management of maintenance annual intervention allowed and availability of the nuclear sector of 82.6%. The safety level was also maintained at a high value. The quality of the supplied electricity has been improved continuously: the annual average interruption duration for low voltage supply has been reduced from 1.35 h in 1996 to 1.06 h in 1997. Sale volume in France (369.9 billion kWh) is 0.7% lower than in 1996. EDF remains the first electricity exporter in Europe. The EDF has strengthened in 1997 its international development. FF 4.2 billions have been invested in Europe, Latin America and Asia. A social policy has been developed in favor of employee, particularly, young people acting toward enterprise's development, better management and working time reduction. In the frame of its relation with the state the EDF Company has signed a new contract for the period 1997-2000 which will allow reaching its ambition: becoming a public service of reference in Europe and its promotion as leader in industrial services, in the electric sector of France and on the international market. The results of this first year has confirmed the course adopted. The report contains the following seven chapters: 1. Relations with the state and the evolution of the institutional frame; 2. The financial results and administration; 3. Technical results; 4. Development in France; 5. International development; 6. Social and human resources; 7. Environment.

Policemen exposure to atmospheric pollutants in Paris; Exposition des policiers aux polluants atmospheriques a Paris

Energy Technology Data Exchange (ETDEWEB)

Bugajny, Ch.; Coursimault, A.; Donati, J.; Vieillard, H. [Laboratoire Central de la Prefecture de Police de Paris, 75 (France); Ducos, P.; Gaudin, R. [Institut National de Recherche et de Securite, 54 - Vandoeuvre les Nancy (France)

2000-07-01

The objective of this study was to evaluate the effects of automotive pollution on police health in Paris, more particularly those that are working near streets and crossroads; police working indoors are included in measurements as a reference population. This work included individual exposure measurements to some urban pollution main indicators and biological determinations to estimate the impact of these pollutants on health. Biological measurements, including determinations of carboxyhemoglobin, lead in blood and trans, trans-muconic acid in urine were realised. Carbon monoxide and benzene individual exposure had been measured by the use of individual analysers and diffusive samplers respectively. Motorcycle policemen and policemen at crossroads are more exposed than reference population working indoor. CO mean exposure levels are 6, 8 mg/m{sup 3} for motorcycle policemen, 5, 4 mg/m{sup 3} for policemen at crossroads, compared to 3, 6 mg/m{sup 3} for policemen working indoors. Carboxyhemoglobin mean values before work are four to five times more important for smokers (4, 5 % HbCO) than no-smokers (1,0%HbCO). After work, these values are respectively 5,3 % and 1,1 %. Non-smokers agents don't reach the OMS value (2,5%HbCO), even after work. Smoking contributes to higher levels of CO in blood than car exhaust pollutants, even for high air pollutants concentrations. Lead blond levels, which average is 45{mu}g/l, are clearly smaller than the OMS value (200{mu}g/l). About non-smokers agents, benzene median exposures are 74 {mu}g/m{sup 3} for motorcycle policemen, 19 {mu}g/m{sup 3} for policemen at crossroads, compared to 8 {mu}g/m{sup 3} for sedentary agents. If motorcycle agents filled up the tank with gasoline, benzene median exposure level is 229 {mu}g/m{sup 3}. Differences between smokers and non-smokers benzene exposure are not significant. For non-smokers agents, median trans, trans muconic acid values after work are 0,06 mg/l for pollution exposed agents

Embedding the logic of the Paris Agreement into the new Regulation on Governance of the Energy Union

International Nuclear Information System (INIS)

Voss-Stemping, Judith; Sartor, Oliver; Colombier, Michel

2017-10-01

To safeguard the climate and to keep the temperatures targets of the Paris Agreement within reach, determined climate action of global players, such as the European Union (EU) and its Member States, is needed more than ever. The Paris Agreement sets out a clear process to review and raise ambition embarking on a long-term transformation of the global economy. To ensure that this process and the logic of the Paris Agreement is adequately embedded in the into the new Regulation on Governance of the Energy Union, IDDRI identifies the long-term strategies, iterative process and inherent time-line of the Paris Agreement as points of vigilance

A Concise Physical Interpretation of Several Analytical Grueneisen Formulations

Science.gov (United States)

2006-08-01

PARIS 75752 FRANCE 1 CEA/CESTA A GEILLE BOX 2 LE BARP 33114 FRANCE 5 CENTRE D’ETUDES DE GRAMAT C LOUPIAS P OUTREBON J...CAGNOUX C GALLIC J TRANCHET GRAMAT 46500 FRANCE 1 DAT ETBS CETAM C ALTMAYER ROUTE DE GUERRY BOURGES 18015 FRANCE 1 FRENCH