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Sample records for par hemagglutination passive

  1. Passive transfer of Anti-Dirofilaria immitis hemagglutinating antibody from the mother dog to its offspring

    OpenAIRE

    Hayasaki, Mineo

    1982-01-01

    Twenty mother dogs, and their 19. fetuses and 57 newborn puppies were examined by the indirect hemagglutination (IHA) test for the transfer of anti-Dirofilaria immitis antibody from mothers to their offspring. The antibody was shown to be passively transferred via colostrum to the puppies and to persist in the puppies for approximately two months. On the other hand, no antibody was detected in the fetuses even when their mothers had high titers. The time-course studies indicated that, on the ...

  2. Application of hepatitis B core particles produced by human primary hepatocellular carcinoma (PLC/342) propagated in nude mice to the determination of anti-HBc by passive hemagglutination.

    Science.gov (United States)

    Miyamoto, K; Itoh, Y; Tsuda, F; Matsui, T; Tanaka, T; Miyamoto, H; Naitoh, S; Imai, M; Usuda, S; Nakamura, T

    1986-05-22

    Human primary hepatocellular carcinoma (PLC/342), carried by nude mice, produces hepatitis B core particles as well as hepatitis B surface antigen particles. Core particles purified form PLC/342 tumors displayed epitopes of hepatitis B core antigen (HBcAg) but not epitopes of hepatitis B e antigen (HBeAg) on their surface, unlike core particles prepared from Dane particles, derived from plasma of asymptomatic carriers, that expressed epitopes of both HBcAg and HBeAg. Core particles obtained from PLC/342 tumors were applied to the determination of antibody to HBcAg (anti-HBc) by passive hemagglutination. The assay detected anti-HBc not only in individuals with persistent infection with hepatitis B virus and in those who had recovered from transient infection, but also in patients with acute type B hepatitis, indicating that it can detect anti-HBc of either IgG or IgM class. A liberal availability of core particles from tumors carried by nude mice, taken together with an easy applicability of the method, would make the passive hemagglutination for anti-HBc a valuable tool in clinical and epidemiological studies, especially in places where sophisticated methods are not feasible.

  3. Development and application of radioimmunoassay and enzyme immunoassays in microbiological and immunological diagnosis. 3. Comparative studies for the detection of virus antibodies with passive hemagglutination test, radioimmunoassay and enzyme immunoassay, resp

    Energy Technology Data Exchange (ETDEWEB)

    Lauf, H; Struy, H; Morenz, J [Medizinische Akademie, Magdeburg (German Democratic Republic)

    1982-06-01

    Radioimmuno- and enzyme immunoassays (solid phase RIA and ELISA) developed by the authors for the determination of antibodies of adeno-2- and parainfluenza-1-viruses are described and the detection sensibility for antibodies is compared with that of the conventional passive hemagglutination test. The sensibility of the radioimmunoassay for the detection of IgG antibodies against adeno-2-viruses is nearly 10 times higher than that of the passive hemagglutination. RIA and ELISA show no essential differences in their detection sensibilities in the detection of IgG antibodies against parainfluenza-1-viruses.

  4. Application of passive auto catalytic recombiner (PAR) for BWR plants in Japan

    International Nuclear Information System (INIS)

    Kobayashi, K.; Murano, K.; Yamanari, S.; Yamamoto, Y.

    2001-01-01

    The passive auto-catalytic recombiner (PAR), which can recombine flammable gases such as hydrogen and oxygen with each other to avoid an explosion in case of a loss-of-coolant accident (LOCA), installed in the primary containment vessel does not require a power supply or dynamic equipment, while the existing flammability gas control system (FCS) of most BWRs as an outer loop of the primary containment vessel needs them to make flammable gases circulate through blowers and heaters in the system. PAR offers a number of advantages over existing FCS, such as high reliability, low cost due to much smaller amount of materials needed, good maintainability, good operability in case of a LOCA, and smaller space for installation. An experimental study has been carried out for the purpose of solving the problems of applying PAR to Japanese BWR plants instead of existing FCS, in which we grasped the basic characteristics of PAR. (author)

  5. Evaluation of Passive Autocatalytic Recombiner (PAR) Implementation in a Konvoi NPP Containment Type

    Energy Technology Data Exchange (ETDEWEB)

    Lopez-Alonso, E.; Papini, D.; Jimenez, G.

    2015-07-01

    The evaluation of Passive Autocatalytic Recombiner (PAR) implementation has been developed under the methodology extracted from the IAEA document, analysing the size, location and number of the PARs capable to minimize the combustion risk, which arises from a hydrogen release generated during a severe accident and its distribution in containment building. A detailed three-dimensional model of Konvoi (PWR) containment with GOTHIC 8.1 code was used for the simulations. The hydrogen preferential pathways and the accumulation points were studied and identified on the basis of a base case scenario without any mitigation measure. The PAR configuration offers an improvement in the chosen accidental scenario; decreasing the possibility of hydrogen combustion and leading to concentration values below the flammability limit (hydrogen concentration below 7%), in all the containment compartments at the end of the transient. Furthermore, from the analysis, it is concluded that the time required to reach hydrogen concentrations below the combustion limit is considerably reduced. (Author)

  6. Hemagglutination treponemal test for syphilis.

    OpenAIRE

    Friedly, G; Zartarian, M V; Wood, J C; Floyd, C M; Peterson, E M; de la Maza, L M

    1983-01-01

    Sera from 290 hospital patients were tested to compare the sensitivity, specificity, and reproducibility of the hemagglutination treponemal test for syphilis (HATTS) with the fluorescent treponemal antibody absorption test (FTA-ABS). Complete agreement was obtained between the methods when 142 syphilitic sera from patients with various stages of syphilis were tested. By using clinical histories, the specificity with 148 nonsyphilitic sera was determined to be 100% for the HATTS and 96.6% (143...

  7. Evaluation of passive autocatalytic recombiners (PARS) performance for a PWR-konvoi containment type with Gothic 8.1 code

    International Nuclear Information System (INIS)

    Lopez-Alonso Conty, E.; Papini, D.; Jimenez Varas, G.

    2016-01-01

    The study presented in this work analyses the evaluation of Passive Autocatalytic Recombiners (PARs) performance for a PWR-Konvoi containment type as a result of an international collaboration between the Paul Scherrer institute (PSI) and the Universidad Politecnica de Madrid (UPM). The implementation study analyzes the size, location and number of the PARs to minimize the risk arising from a hydrogen release and its distribution in the containment building during a hypothetical severe accident. A detailed 3D model of containment was used for the simulations developed for the Gothic 8.1 code. In the first place, the hydrogen preferential pathways and points of hydrogen accumulation were studies and identified starting from the base case scenario without any mitigation measure. The severe accident scenario chosen is a fast release of hydrogen-steam mixture from hot leg creep rupture during SBO (Station Black-Out) accident. Secondly a configuration of PARs was simulated under the same conditions of the unmitigated case. The PAR configuration offered an improvement in the chosen accident scenario, decreasing the hydrogen concentration values below the flammability limit /hydrogen concentration below 7%) in all the containment compartments. (Author)

  8. Understanding of the operation behaviour of a Passive Autocatalytic Recombiner (PAR) for hydrogen mitigation in realistic containment conditions during a severe Light Water nuclear Reactor (LWR) accident

    International Nuclear Information System (INIS)

    Payot, Frédéric; Reinecke, Ernst-Arndt; Morfin, Franck; Sabroux, Jean-Christophe; Meynet, Nicolas; Bentaib, Ahmed; March, Philippe; Zeyen, Roland

    2012-01-01

    Highlights: ► Recombineur operation in the presence of fission products (severe accident conditions). ► Operation of catalysts in the integral and small-scale tests. ► The catalyst performance was observed by measuring the coupon temperature increase. ► The experimental observations were corroborated by numerical calculations (SPARK code). - Abstract: In the context of hydrogen risk mitigation in nuclear power plants (NPPs), experimental studies of a possible poisoning of Passive Autocatalytic Recombiners (PARs) by fission products (FPs) and aerosols released during a core meltdown accident were mainly conducted in the past with non-radioactive fission product surrogates (e.g., in the H2PAR facility at Cadarache, France). The decision was taken in 1997 to complete these studies by a test in the Phébus facility, a research nuclear reactor also at Cadarache: it was a rare opportunity to expose catalyst samples to an atmosphere as representative as possible of a core meltdown accident, containing gaseous fission products and aerosols released during the degradation of an actual irradiated nuclear fuel bundle. Before testing in Phébus during the FPT3 experiment, reference and qualification tests were performed in the H2PAR facility using the same samples — the so-called “coupons” — and coupons holder to check that the apparatus was functional and correctly designed for avoiding to tamper with the thermal-hydraulics and chemical conditions in the Phébus containment. The correct operation of catalysts was checked by measuring the surface temperature increase of the coupons due to the exothermic reaction between hydrogen and oxygen. After the Phébus FPT3 test (November 2004), REKO-1 tests were initiated at Jülich, Germany, to confirm the discrepancy in coupons temperature observed in Phébus FPT3 and H2PAR PHEB-03 tests, and to study the operation behaviour of PARs. Besides, before REKO-1 tests, a first interpretation of H2PAR and Phébus experiments

  9. Effects Of Chinese Herbs On The Hemagglutination And Adhesion ...

    African Journals Online (AJOL)

    The aim of this study is to evaluate Chinese herbs' efficacy on adhesive properties of Escherichia coli (E. coli). The effects of Chinese herbal solution on the hemagglutination and adhesion by E. coli strain were studied. E. coli C16 was isolated from a patient with urinary tract infection. The MIC value of herbal solution for the ...

  10. Cálculo de parámetros de filtros pasivos de armónicos; Calculation of the harmonics passive filters parameters

    Directory of Open Access Journals (Sweden)

    Ignacio Pérez Abril

    2012-07-01

    Full Text Available Los filtros de armónicos cumplen la función de evitar la circulación de las corrientes de armónico por el sistema y reducir la distorsión de la tensión. Estos pueden ser pasivos (compuestos por arreglos de impedancias o activos(basados en electrónica de potencia. Las características de los filtros pasivos pueden encontrarse en la bibliografía especializada. Sin embargo, las ecuaciones para el diseño de los mismos no se muestran en todos los casos, lo que dificulta el cálculo de sus componentes y de su estrés en condiciones de operación. El objetivo fundamental de este trabajo es desarrollar el procedimiento general para el cálculo de los filtros pasivos de armónicos y determinar las ecuaciones correspondientes a los distintos tipos de filtro. Además, se describe una aplicación en Matlab que calcula los parámetros R, L y C de los distintos tipos de filtro y evalúa el estrés a que se someten los componentes de los mismos. The purpose of the harmonic filters in the electrical power systems is the avoiding the harmonic currents circulation in the network and the reduction of the voltages waveform distortion. The harmonic filters can be of passive type (composite of impedances or active type (based on power electronic. The characteristics of passive filters can be found in the specialized bibliography. However, the equations for the filter design are not showed in all cases, which difficult the filter’s components calculation and the evaluation of its stress in operation conditions. The objective of thepresented work is the developing of a general procedure for the harmonic passive filters parameters calculation and the determination of the needed equations for each type of filter. Besides, a Matlab application that calculates the R, L and C parameters, and the stress of all the treated filters is showed.

  11. Evaluation of Hemagglutination Activity of Chitosan Nanoparticles Using Human Erythrocytes

    Directory of Open Access Journals (Sweden)

    Jefferson Muniz de Lima

    2015-01-01

    Full Text Available Chitosan is a polysaccharide composed of randomly distributed chains of β-(1-4 D-glucosamine and N-acetyl-D-glucosamine. This compound is obtained by partial or total deacetylation of chitin in acidic solution. The chitosan-based hemostatic agents have been gaining much attention in the management of bleeding. The aim of this study was to evaluate in vitro hemagglutination activity of chitosan nanoparticles using human erythrocytes. The preparation of nanoparticles was achieved by ionotropic gelification technique followed by neutralization with NaOH 1 mol/L−1. The hemagglutination activity was performed on a solution of 2% erythrocytes (pH 7.4 on PBS collected from five healthy volunteers. The hemolysis determination was made by spectrophotometric analysis. Chitosan nanoparticle solutions without NaOH addition changed the reddish colour of the wells into brown, suggesting an oxidative reaction of hemoglobin and possible cell lysis. All neutralized solutions of chitosan nanoparticles presented positive haemagglutination, without any change in reaction color. Chitosan nanoparticles presented hemolytic activity ranging from 186.20 to 223.12%, while neutralized solutions ranged from 2.56 to 72.54%, comparing to distilled water. Results highlight the need for development of new routes of synthesis of chitosan nanoparticles within human physiologic pH.

  12. Altered indirect hemagglutination method for easy serotyping of Haemophilus parasuis

    Directory of Open Access Journals (Sweden)

    M.S. Lorenson

    Full Text Available ABSTRACT Glässer's disease is an emergent bacterial disease that affects swine husbandries worldwide causing important economic losses. The aetiological agent, Haemophilus parasuis, is currently divided in fifteen serovars but an increasing number of non-typeable serovars have been reported. Indirect hemagglutination (IHA is indicated as a serotyping method for H. parasuis. In the present study, we describe an additional step that aims to work around a possible obstacle in the original protocol that may compromise the outcome of this assay. We observed that the choice of anticoagulant for blood collection influences and/or impairs spontaneous adsorption of H. parasuis antigens on sheep red blood cells (SRBCs. However, regardless of the anticoagulant used, chemical treatment of SRBCs with tannic acid induces a stable antigen adsorption (sensitization step. The addition of 1% BSA to SRBCs washing buffer and to antisera dilution augments IHA specificity. Tannic acid treated SRBCs combined with thermo-resistant H. parasuis antigens increases the assay resolution. Thus, our results demonstrate an improvement in the technique of H. parasuis serotyping that will prove valuable to understand Glässer's disease epidemiology and to better characterize serovars involved in outbreaks.

  13. Evaluation of passive autocatalytic recombiners (PARS) performance for a PWR-konvoi containment type with Gothic 8.1 code; Evaluacion de la implementacion de recombinadores autocataliticos pasivos (PAR) en una contencion tipo Konvoi con el codigo Gothic 8.1

    Energy Technology Data Exchange (ETDEWEB)

    Lopez-Alonso Conty, E.; Papini, D.; Jimenez Varas, G.

    2016-08-01

    The study presented in this work analyses the evaluation of Passive Autocatalytic Recombiners (PARs) performance for a PWR-Konvoi containment type as a result of an international collaboration between the Paul Scherrer institute (PSI) and the Universidad Politecnica de Madrid (UPM). The implementation study analyzes the size, location and number of the PARs to minimize the risk arising from a hydrogen release and its distribution in the containment building during a hypothetical severe accident. A detailed 3D model of containment was used for the simulations developed for the Gothic 8.1 code. In the first place, the hydrogen preferential pathways and points of hydrogen accumulation were studies and identified starting from the base case scenario without any mitigation measure. The severe accident scenario chosen is a fast release of hydrogen-steam mixture from hot leg creep rupture during SBO (Station Black-Out) accident. Secondly a configuration of PARs was simulated under the same conditions of the unmitigated case. The PAR configuration offered an improvement in the chosen accident scenario, decreasing the hydrogen concentration values below the flammability limit /hydrogen concentration below 7%) in all the containment compartments. (Author)

  14. Estimation de l'equivalent en eau de la neige en milieu subarctique du Quebec par teledetection micro-ondes passives

    Science.gov (United States)

    Vachon, Francois

    The snow cover (extent, depth and water equivalent) is an important factor in assessing the water balance of a territory. In a context of deregulation of electricity, better knowledge of the quantity of water resulting from snowmelt that will be available for hydroelectric power generation has become a major challenge for the managers of Hydro-Quebec's generating plant. In fact, the snow on the ground represents nearly one third of Hydro-Quebec's annual energy reserve and the proportion is even higher for northern watersheds. Snowcover knowledge would therefore help optimize the management of energy stocks. The issue is especially important when one considers that better management of water resources can lead to substantial economic benefits. The Research Institute of Hydro-Quebec (IREQ), our research partner, is currently attempting to optimize the streamfiow forecasts made by its hydrological models by improving the quality of the inputs. These include a parameter known as the snow water equivalent (SWE) which characterizes the properties of the snow cover. At the present time, SWE data is obtained from in situ measurements, which are both sporadic and scattered, and does not allow the temporal and spatial variability of SWE to be characterized adequately for the needs of hydrological models. This research project proposes to provide the Quebec utility's hydrological models with distributed SWE information about its northern watersheds. The targeted accuracy is 15% for the proposed period of analysis covering the winter months of January, February and March of 2001 to 2006. The methodology is based on the HUT snow emission model and uses the passive microwave remote sensing data acquired by the SSM/I sensor. Monitoring of the temporal and spatial variations in SWE is done by inversion of the model and benefits from the assimilation of in situ data to characterize the state of snow cover during the season. Experimental results show that the assimilation technique

  15. Hemagglutinating and acid phosphatase (AcPASE activities in developing seedlings of four species of Cucurbitaceae

    Directory of Open Access Journals (Sweden)

    Irena Lorenc-Kubis

    2014-01-01

    Full Text Available The acid phosphatase and hemagglutinating activities of four species of Cucurbitaceae were determined during seeds germination and seedlings development. In all cases traces of enzyme and hemagglutinating activities were found in dry and imbibided seeds. In developing seedlings of Cucumis sativus the activities increased to maximum on the 3rd day while in other species on the 6th day of germination and than fell down. Dot blot and Western blot techniques have shown that in seeds and seedlings of all investigated species present were proteins which cross-reacted with antibodies raised against lectins: CLBa and Con A. It has been shown that proteins from seeds and seedlings of Cucurbita maxima var. bambino, Cucurbita pepo var. giromontia and Cucumis sativus had more pronounced antigenical similarity to lectin CLBa (from Cucurbitaceae than Con A, while proteins from cotyledons of Cucurbita pepo var. patissonina reacted better with antibodies raised against Con A (the lectin from Papilionaceae than with CLBa.

  16. Effect of extracytoplasmic function sigma factors on autoaggregation, hemagglutination, and cell surface properties of Porphyromonas gingivalis

    Science.gov (United States)

    Kokubu, Eitoyo; Okamoto-Shibayama, Kazuko; Ishihara, Kazuyuki

    2017-01-01

    Porphyromonas gingivalis is a bacterium frequently isolated from chronic periodontal lesions and is involved in the development of chronic periodontitis. To colonize the gingival crevice, P. gingivalis has to adapt to environmental stresses. Microbial gene expression is regulated by transcription factors such as those in two-component systems and extracytoplasmic function (ECF) sigma factors. ECF sigma factors are involved in the regulation of environmental stress response genes; however, the roles of individual ECF sigma factors are largely unknown. The purpose of this study was to investigate the functions, including autoaggregation, hemagglutination, gingipain activity, susceptibility to antimicrobial agents, and surface structure formation, of P. gingivalis ECF sigma factors encoded by SigP (PGN_0274), SigCH (PGN_0319), PGN_0450, PGN_0970, and SigH (PGN_1740). Various physiological aspects of the sigP mutant were affected; autoaggregation was significantly decreased at 60 min (p < 0.001), hemagglutination activity was markedly reduced, and enzymatic activities of Kgp and Rgps were significantly decreased (p < 0.001). The other mutants also showed approximately 50% reduction in Rgps activity. Kgp activity was significantly reduced in the sigH mutant (p < 0.001). No significant differences in susceptibilities to tetracycline and ofloxacin were observed in the mutants compared to those of the wild-type strain. However, the sigP mutant displayed an increased susceptibility to ampicillin, whereas the PGN_0450 and sigH mutants showed reduced susceptibility. Transmission electron microscopy images revealed increased levels of outer membrane vesicles formed at the cell surfaces of the sigP mutant. These results indicate that SigP is important for bacterial surface-associated activities, including gingipain activity, autoaggregation, hemagglutination, vesicle formation, and antimicrobial susceptibility. PMID:28931045

  17. Crystal structure of a plant albumin from Cicer arietinum (chickpea) possessing hemopexin fold and hemagglutination activity.

    Science.gov (United States)

    Sharma, Urvashi; Katre, Uma V; Suresh, C G

    2015-05-01

    Crystal structure of a reported PA2 albumin from Cicer arietinum shows that it belongs to hemopexin fold family, has four beta-propeller motifs and possesses hemagglutination activity, making it different from known legume lectins. A plant albumin (PA2) from Cicer arietinum, presumably a lectin (CAL) owing to its hemagglutination activity which is inhibited by complex sugars as well as glycoproteins such as fetuin, desialylated fetuin and fibrinogen. The three-dimensional structure of this homodimeric protein has been determined using X-ray crystallography at 2.2 Å in two crystal forms: orthorhombic (P21212) and trigonal (P3). The structure determined using molecular replacement method and refined in orthorhombic crystal form reached R-factors R free 22.6 % and R work 18.2 % and in trigonal form had 22.3 and 17.9 % in the resolution range of 20.0-2.2 and 35.3-2.2 Å, respectively. Interestingly, unlike the known legume lectin fold, the structure of this homodimeric hemagglutinin belonged to hemopexin fold that consisted of four-bladed β-propeller architecture. Each subunit has a central cavity forming a channel, inside of which is lined with hydrophobic residues. The channel also bears binding sites for ligands such as calcium, sodium and chloride ions, iodine atom in the case of iodine derivative and water molecules. However, none of these ligands seem important for the sugar recognition. No monosaccharide sugar specificity could be detected using hemagglutination inhibition. Chemical modification studies identified a potential sugar-binding site per subunit molecule. Comparison of C-alpha atom positions in subunit structures showed that the deviations between the two crystal forms were more with respect to blades I and IV. Differences also existed between subunits in two forms in terms of type and site of ligand binding.

  18. CFD analysis of PAR performance as function of inlet design

    Energy Technology Data Exchange (ETDEWEB)

    Park, Kweonha, E-mail: khpark@kmou.ac.kr [Division of Mechanical and Energy systems Engineering, Korea Maritime University, Dongsam-dong, Yeongdo-gu, Busan 606-791 (Korea, Republic of); Khor, Chong Lee, E-mail: itachi_829@hotmail.com [Department of Mechanical Engineering, Korea Maritime University (Korea, Republic of)

    2016-01-15

    Highlights: • The new concept of PAR (passive autocatalytic recombiner) was proposed and analyzed. • Guidance wall was added at the bottom of PAR to enhance the flow rate through the catalyst. • The new concept of PAR was proved to have a better hydrogen removal performance. - Abstract: Passive autocatalytic recombiner (PAR) is very useful hydrogen mitigation measurement. It is widely implemented in the current and advanced light water reactors (ALWRs). The design of the PARs should be optimized for the specific use under severe accident scenarios. Several techniques and innovations have been fused into the PAR, as an effort to increase its efficiency of hydrogen mitigation. This study proposes different concepts of PAR, which applied some changes to the honeycomb catalyst PAR made by the Korea Nuclear Technology (KNT) Inc. Two slices of plate are added to the bottom of PAR model, which intended to act as a reflection wall and promote the gas flow into PAR. Hydrogen volume fraction was given 4 vol. % which tested by KNT to investigate the performance of PAR in different direction gas flow conditions to see maximum hydrogen recombination rate. The new concept of PAR was proved to have a better hydrogen removal performance compared to the original honeycomb catalyst PAR.

  19. CFD analysis of PAR performance as function of inlet design

    International Nuclear Information System (INIS)

    Park, Kweonha; Khor, Chong Lee

    2016-01-01

    Highlights: • The new concept of PAR (passive autocatalytic recombiner) was proposed and analyzed. • Guidance wall was added at the bottom of PAR to enhance the flow rate through the catalyst. • The new concept of PAR was proved to have a better hydrogen removal performance. - Abstract: Passive autocatalytic recombiner (PAR) is very useful hydrogen mitigation measurement. It is widely implemented in the current and advanced light water reactors (ALWRs). The design of the PARs should be optimized for the specific use under severe accident scenarios. Several techniques and innovations have been fused into the PAR, as an effort to increase its efficiency of hydrogen mitigation. This study proposes different concepts of PAR, which applied some changes to the honeycomb catalyst PAR made by the Korea Nuclear Technology (KNT) Inc. Two slices of plate are added to the bottom of PAR model, which intended to act as a reflection wall and promote the gas flow into PAR. Hydrogen volume fraction was given 4 vol. % which tested by KNT to investigate the performance of PAR in different direction gas flow conditions to see maximum hydrogen recombination rate. The new concept of PAR was proved to have a better hydrogen removal performance compared to the original honeycomb catalyst PAR.

  20. Toxoplasmosis serology: an efficient hemagglutination procedure to detect IgG and IgM antibodies

    Directory of Open Access Journals (Sweden)

    M.E. Camargo

    1989-08-01

    Full Text Available In search of an efficient but simple, low cost procedure for the serodiagnosis of Toxoplasmosis, especially suited for routine laboratories facing technical and budget limitations as in less developed countries, the diagnostic capability of Hematoxo® , an hemagglutination test for toxoplasmosis, was evaluated in relation to a battery of tests including IgG- and IgM-immunofluorescence tests, hemagglutination and an IgM-capture enzymatic assay. Detecting a little as 5 I.U. of IgG antitoxoplasma antibodies, Hematoxo® showed a straight agreement as to reactivity and non-reactivity for the 443 non-reactive and the 387 reactive serum samples, included in this study. In 23 cases presenting a serological pattern of acute toxoplasmosis and showing IgM antibodies, Hematoxo® could detect IgM antibodies in 18, indicated by negativation or a significant decrease in titers as a result of treating samples with 2-mercapto-ethanol. However, a neat increase in sensitivity for IgM specific antibodies could be achieved by previously removing IgG from the sample, as demonstrated in a series of acute toxoplasmosis sera. A simple procedure was developed for this purpose, by reconstituting a lyophilized suspension of Protein A - rich Staphylococcus with the lowest serum dilution to be tested. Of low cost and easy to perform, Hematoxo® affords not only a practical qualitative procedure for screening reactors and non-reactors, as in prenatal services, but also quantitative assays that permit to titrate antibodies as well as to identify IgM antibodies.

  1. Passive safety; Passive Sicherheit

    Energy Technology Data Exchange (ETDEWEB)

    Rueckert, J. [Skoda Auto a.s., Mlada Boleslav (Czech Republic). Interieurentwicklung und Versuche; Hau, M. [Skoda Auto a.s., Mlada Boleslav (Czech Republic). Koordination der Fahrzeugsicherung

    2004-05-01

    The specifications for passive safety are partly based on the legal requirements for all export markets combined with the strict internal standards of Volkswagen Group. The Euro NCAP tests and their precisely defined testing methods using the new point assessment are very important. (orig.)

  2. Separation of hemagglutination-inhibiting immunoglobulin M antibody to rubella virus in human serum by high-performance liquid chromatography.

    OpenAIRE

    Kobayashi, N; Suzuki, M; Nakagawa, T; Matumoto, M

    1986-01-01

    High-performance liquid chromatography was successfully used to separate hemagglutination-inhibiting immunoglobulin M (IgM) rubella virus antibody from IgG rubella virus antibody in human serum. The fractionation by high-performance liquid chromatography was as effective as sucrose density gradient centrifugation in separating IgM antibody from IgG antibody.

  3. Comparisons of Venezuelan encephalitis virus strains by hemagglutination-inhibition tests with chicken antibodies.

    Science.gov (United States)

    Scherer, W F; Pancake, B A

    1977-01-01

    Twenty strains of Venezuelan encephalitis (VE) virus inoculated intravenously in large doses into roosters produced hemagglutination-inhibition (HI) antibodies detectable in plasmas within 7 to 10 days. No signs of illness occurred, and there was no evidence of viral growth in tissues since blood concentrations of infectious virus steadily decreased after inoculation. HI antibodies in early plasmas were specific for VE virus and did not cross-react significantly with two other North American alphaviruses, eastern and western encephalitis viruses. VE virus strains could be distinquished by virus-dilution, short-incubation HI, but not by plasma-dilution neutralization tests, by using early rooster antibodies. The distinctions by HI test were similar with some strains to, but different with other strains from, those described by Young and Johnson with the spiny rat antisera used to establish their subtype classifications of VE virus (14, 28). Nevertheless, results of HI tests with rooster antibodies correlated with equine virulence, as did results with spiny rat antibodies, and distinguished the new strains of virus that appeared in Middle America during the VE outbreak of 1969 from preexisting strains. PMID:591629

  4. Hemagglutination detection for blood typing based on waveguide-mode sensors

    Directory of Open Access Journals (Sweden)

    Hiroki Ashiba

    2015-03-01

    Full Text Available ABO and Rh(D blood typing is one of the most important tests performed prior to blood transfusion. Although on-site blood testing is desirable for expedient blood transfusion procedure, most conventional methods and instruments lack the required usability or portability. Here, we describe a novel method, based on the detection of hemagglutination using an optical waveguide-mode sensor, for on-site use. The reflectance spectrum of blood alone and that of blood mixed with antibody reagents was measured using the waveguide-mode sensor. Differences in reflectance by agglutinated and non-agglutinated blood samples were observed at the bottom of the spectral dips; due to differences in the manner in which red blood cells interacted with the surface of the sensor chip. Following the addition of the antibody, blood types A, B, O, and AB were clearly distinguishable and Rh(D typing was also possible using the waveguide-mode sensor. Furthermore, the waveguide-mode-based measurement exhibited the potential to detect weak agglutination, which is difficult for human eyes to distinguish. Thus, this method holds great promise for application in novel on-site test instruments.

  5. Increased Frequency of ColV Plasmids and Mannose-Resistant Hemagglutinating Activity in an Escherichia coli K1 Population

    OpenAIRE

    1984-01-01

    The expression of traits linked to pathogenicity was studied in a population of Escherichia coli K1 strains. It was found that E. coli K1 strains isolated from extraintestinal infection harbor the ColV plasmid and express mannose-resistant hemagglutinating activity type VI with a high frequency. The presence of these properties may play a role in the ability of some E. coli K1 serogroups to invade.

  6. Assessment of Anti-Influenza Activity and Hemagglutination Inhibition of Plumbago indica and Allium sativum Extracts.

    Science.gov (United States)

    Chavan, Rahul Dilip; Shinde, Pramod; Girkar, Kaustubh; Madage, Rajendra; Chowdhary, Abhay

    2016-01-01

    Human influenza is a seasonal disease associated with significant morbidity and mortality. Anti-flu ayurvedic/herbal medicines have played a significant role in fighting the virus pandemic. Plumbagin and allicin are commonly used ingredients in many therapeutic remedies, either alone or in conjunction with other natural substances. Evidence suggests that these extracts are associated with a variety of pharmacological activities. To evaluate anti-influenza activity from Plumbago indica and Allium sativum extract against Influenza A (H1N1)pdm09. Different extraction procedures were used to isolate the active ingredient in the solvent system, and quantitative HPLTC confirms the presence of plumbagin and allicin. The cytotoxicity was carried out on Madin-Darby Canine kidney cells, and the 50% cytotoxic concentration (CC50) values were below 20 mg/mL for both plant extracts. To assess the anti-influenza activity, two assays were employed, simultaneous and posttreatment assay. A. sativum methanolic and ethanolic extracts showed only 14% reduction in hemagglutination in contrast to P. indica which exhibited 100% reduction in both simultaneous and posttreatment assay at concentrations of 10 mg/mL, 5 mg/mL, and 1 mg/mL. Our results suggest that P. indica extracts are good candidates for anti-influenza therapy and should be used in medical treatment after further research. The search for natural antiviral compounds from plants is a promising approach in the development of new therapeutic agents. In the past century, several scientific efforts have been directed toward identifying phytochemicals capable of inhibiting virus. Knowledge of ethnopharmacology can lead to new bioactive plant compounds suitable for drug discovery and development. Macromolecular docking studies provides most detailed possible view of drug-receptor interaction where the structure of drug is designed based on its fit to three dimensional structures of receptor site rather than by analogy to other

  7. Characterization of hemagglutination activity of emerging Newcastle disease virus in Bangladesh

    Directory of Open Access Journals (Sweden)

    Helal Uddin

    2017-06-01

    Full Text Available Aim: Newcastle disease (ND is an important viral disease for poultry caused by avian paramyxovirus which can be identified by its nature of agglutination activity with red blood cell (RBC of different species. The study was aimed to characterize the hemagglutinating (HA activity of ND virus (NDV at three different temperatures using RBC of five avian species, six mammalian species, and eight different human blood groups. Materials and Methods: The study was conducted from January to December 2014 at Chittagong Veterinary and Animal Sciences University. Five avian and six different mammalian species were selected for the study. In each species, two blood samples were collected aseptically. Eight different blood groups (A+, A−, B+, B−, AB+, AB−, O+, and O− were studied in human. HA test was performed using two virus strains ND lasota and field isolate of very virulent NDV (VVNDV with mentioned species of RBC at chilling (4°C, incubating (37°C, and room temperature (24°C. Results: Avian RBC requires less time for agglutination than mammalian RBC. Incubation temperature (37°C requires lowest time and chilling temperature requires highest time for agglutination of RBC. Duck RBC requires lowest time (17.81 min while chicken RBC needs highest (57.5 min time for HA at incubation temperature and at chilling temperature, respectively, against ND lasota virus and with field strain. Goat RBC requires significantly higher time for HA (184.68 min at chilling temperature than other mammalian species. Human RBC requires almost similar time but O+ and O− blood group do not show any HA activity. Significant variation (p<0.05 found in quail RBC at incubation temperature. In mammalian species, a significant difference (p<0.05 has been observed in goat and horse RBC at chilling; horse and dog RBC at incubation; goat, horse, buffalo, and dog RBC at room temperature. In human, significant variation (p<0.05 has been found in A+, A− and B− blood group

  8. In Vitro inhibitory activity of Alpinia katsumadai extracts against influenza virus infection and hemagglutination

    Directory of Open Access Journals (Sweden)

    Park Su-Jin

    2010-11-01

    Full Text Available Abstract Background Alpinia katsumadai (AK extracts and fractions were tested for in vitro antiviral activities against influenza virus type A, specially human A/PR/8/34 (H1N1 and avian A/Chicken/Korea/MS96/96 (H9N2, by means of time-of-addition experiments; pre-treatment, simultaneous treatment, and post treatment. Results In pre-treatment assay, the AK extracts and AK fractions did not show significant antiviral activity. During the simultaneous treatment assay, one AK extract and five AK fractions designated as AK-1 to AK-3, AK-5, AK-10, and AK-11 showed complete inhibition of virus infectivity against A/PR/8/34 (H1N1 and A/Chicken/Korea/MS96/96 (H9N2. The 50% effective inhibitory concentrations (EC50 of these one AK extracts and five AK fractions with exception of the AK-9 were from 0.8 ± 1.4 to 16.4 ± 4.5 μg/mL against A/PR/8/34 (H1N1. The two AK extracts and three AK fractions had EC50 values ranging from μg/mL against A/Chicken/Korea/MS96/96 (H9N2. By the hemagglutination inhibition (HI assay, the two AK extracts and five AK fractions completely inhibited viral adsorption onto chicken RBCs at less than 100 μg/mL against both A/PR/8/34 (H1N1 and A/Chicken/Korea/MS96/96 (H9N2. Interestingly, only AK-3 was found with inhibition for both viral attachment and viral replication after showing extended antiviral activity during the post treatment assay and quantitative real-time PCR. Conclusions These results suggest that AK extracts and fractions had strong anti-influenza virus activity that can inhibit viral attachment and/or viral replication, and may be used as viral prophylaxis.

  9. Passive Education

    Science.gov (United States)

    Bojesen, Emile

    2018-01-01

    This paper does not present an advocacy of a passive education as opposed to an active education nor does it propose that passive education is in any way 'better' or more important than active education. Through readings of Maurice Blanchot, Jacques Derrida and B.S. Johnson, and gentle critiques of Jacques Rancière and John Dewey, passive…

  10. The passive autocatalytic recombiner test program at Sandia National Laboratories

    International Nuclear Information System (INIS)

    Blanchat, T.K.; Malliakos, A.

    1998-01-01

    Sandia National Laboratories (SNL) has developed systems and methodologies to measure the amount of hydrogen that can be depleted in a containment by a passive autocatalytic recombiner (PAR). Experiments were performed that determined the hydrogen depletion rate of a PAR in the presence of steam and also evaluated the effect of scale (number of cartridges) on the PAR performance at both low and high hydrogen concentrations. (author)

  11. suPAR

    DEFF Research Database (Denmark)

    Hodges, Gethin W; Bang, Casper N; Wachtell, Kristian

    2015-01-01

    The fundamental role of inflammation in cardiovascular disease (CVD) has prompted interest in numerous biomarkers that detect subclinical levels of inflammation. Soluble urokinase plasminogen activator receptor (suPAR) is a novel biomarker that correlates significantly with cardiovascular events ...... comprehensive review of suPAR in CVD and explore its function and usefulness in predicting cardiovascular events....

  12. Purification and Characterization of Hemagglutinating Proteins from Poker-Chip Venus (Meretrix lusoria and Corbicula Clam (Corbicula fluminea

    Directory of Open Access Journals (Sweden)

    Chin-Fu Cheng

    2012-01-01

    Full Text Available Hemagglutinating proteins (HAPs were purified from Poker-chip Venus (Meretrix lusoria and Corbicula clam (Corbicula fluminea using gel-filtration chromatography on a Sephacryl S-300 column. The molecular weights of the HAPs obtained from Poker-chip Venus and Corbicula clam were 358 kDa and 380 kDa, respectively. Purified HAP from Poker-chip Venus yielded two subunits with molecular weights of 26 kDa and 29 kDa. However, only one HAP subunit was purified from Corbicula clam, and its molecular weight was 32 kDa. The two Poker-chip Venus HAPs possessed hemagglutinating ability (HAA for erythrocytes of some vertebrate animal species, especially tilapia. Moreover, HAA of the HAP purified from Poker-chip Venus was higher than that of the HAP of Corbicula clam. Furthermore, Poker-chip Venus HAPs possessed better HAA at a pH higher than 7.0. When the temperature was at 4°C–10°C or the salinity was less than 0.5‰, the two Poker-chip Venus HAPs possessed better HAA compared with that of Corbicula clam.

  13. Par Pond water balance

    International Nuclear Information System (INIS)

    Hiergesell, R.A.; Dixon, K.L.

    1996-06-01

    A water budget for the Par Pond hydrologic system was established in order to estimate the rate of groundwater influx to Par Pond. This estimate will be used in modeling exercises to predict Par Pond reservoir elevation and spillway discharge in the scenario where Savannah River water is no longer pumped and discharged into Par Pond. The principal of conservation of mass was used to develop the water budget, where water inflow was set equal to water outflow. Components of the water budget were identified, and the flux associated with each was determined. The water budget was considered balanced when inflow and outflow summed to zero. The results of this study suggest that Par Pond gains water from the groundwater system in the upper reaches of the reservoir, but looses water to the groundwater system near the dam. The rate of flux of groundwater from the water table aquifer into Par Pond was determined to be 13 cfs. The rate of flux from Par Pond to the water table aquifer near the dam was determined to be 7 cfs

  14. FooPar

    DEFF Research Database (Denmark)

    Hargreaves, F. P.; Merkle, D.

    2013-01-01

    We present FooPar, an extension for highly efficient Parallel Computing in the multi-paradigm programming language Scala. Scala offers concise and clean syntax and integrates functional programming features. Our framework FooPar combines these features with parallel computing techniques. Foo......, results based on a empirical analysis on two supercomputers are given. We achieve close-to-optimal performance wrt. theoretical peak performance. Based on this result we conclude that FooPar allows programmers to fully access Scalas design features without suffering from performance drops when compared...

  15. Unusual spontaneous cold auto-hemagglutination phenomenon in blood units stored under blood bank condition: A retrospective analysis

    Directory of Open Access Journals (Sweden)

    Sanmukh R Joshi

    2015-01-01

    Full Text Available Background: Cold agglutinins (CA are benign naturally occurring low titer autoantibodies present in most individuals. Those with moderate strength are found in infections, malignancies or autoimmune conditions with diagnostic importance. Aim: Present report deals with CA that brought spontaneous hemagglutination in blood units stored at 2-6°C. Study design: Over 32 months period between July 1993 and December 1995, blood units were inspected for spontaneous cold auto-hemagglutination (SpCA phenomenon. The plasma from these units was separated and investigated for serological specificity using in house red cell panel and standard serological methods. Results: Among 51,671 blood units, 112 units showed SpCA phenomenon. A rising trend seen in first half of study period significantly fell in remaining half. Specificities of the antibodies detected include anti-I (27, anti-i (53, anti-Pr (21 with remaining few being undetermined specificity. Absorption of serum using enzyme-treated red cells revealed a presence of anti-Pr among the cases, the two of which with new specificities that reacted preferentially with red cells from either new-born or adults and were tentatively named as anti-Pr Fetal and anti-Pr adult , respectively. While 9 cases showed optimum reaction at neutral pH of 7, 68 (62% cases reacted at pH 5.8 through 8.0, 28 (26% cases preferred an acidic pH 5.8 and 4 cases opted an alkaline pH 8. Of 28 cases with antibodies preferentially reacting in acidic medium, 17 (60% cases were anti-i and 7 (25% cases were anti-Pr. Conclusion: Unique SpCA phenomenon observed in blood units stored under blood bank conditions seems to be due to CA developed in response to vector-borne infectious agents. Majority of the cases displayed their specificities, otherwise are rare to be encountered.

  16. Testing of a passive autocatalytic recombiner in the Surtsey facility

    International Nuclear Information System (INIS)

    Blanchat, T.K.; Malliakos, A.C.

    2000-01-01

    Passive autocatalytic recombiners (PARs) have been under consideration in the US as a combustible gas control system in operating plants and advanced light water reactor containments for design-basis accidents. Here, performance tests of a scaled passive autocatalytic recombiner (PAR) were performed in the Surtsey test vessel at Sandia National laboratories. Measured hydrogen depletion rate data were obtained and compared with previous work. Depletion rate is most likely proportional to PAR scale. PAR performance in steamy environments (with and without hydrophobic coating) was investigated. The tests determined that the PAR startup delay times decrease with increasing hydrogen concentrations in steamy environments. Tests with placement of the PAR near a wall (as opposed to a center location) yielded reduced depletion rates. Tests at low oxygen concentrations also showed a reduced recombination rate. The PAR repeatedly ignited hydrogen at ∼6 mol% concentration with a catalyst temperature near 940 K. Velocity data at the PAR exhaust were used to calculate the volumetric flow rate through the PAR as a function of the vessel hydrogen concentration

  17. It's quicker "Par Avignon"!

    CERN Multimedia

    2005-01-01

    For a few years, the CERN Library has been receiving books from the University of Hanover sent via Avignon, at least that's what it says on the envelope. Such a detour would mean that parcels were travelling 720 km more than the distance separating Geneva and Hanover, which would be a very strange state of affairs. The explanation lies in a spelling mistake. The sender has been stamping parcels with a stamp that says "Par Avignon prioritaire" (first-class via Avignon) instead of "Par Avion prioritaire" (First Class Air Mail), a source of much amusement to the librarians!

  18. PARs for combustible gas control in advanced light water reactors

    International Nuclear Information System (INIS)

    Hosler, J.; Sliter, G.

    1997-01-01

    This paper discusses the progress being made in the United States to introduce passive autocatalytic recombiner (PAR) technology as a cost-effective alternative to electric recombiners for controlling combustible gas produced in postulated accidents in both future Advanced Light Water Reactors (ALWRs) and certain U. S. operating nuclear plants. PARs catalytically recombine hydrogen and oxygen, gradually producing heat and water vapor. They have no moving parts and are self-starting and self-feeding, even under relatively cold and wet containment conditions. Buoyancy of the hot gases they create sets up natural convective flow that promotes mixing of combustible gases in a containment. In a non-inerted ALWR containment, two approaches each employing a combination of PARs and igniters are being considered to control hydrogen in design basis and severe accidents. In pre-inerted ALWRs, PARs alone control radiolytic oxygen produced in either accident type. The paper also discusses regulatory feedback regarding these combustible gas control approaches and describes a test program being conducted by the Electric Power Research Institute (EPRI) and Electricite de France (EdF) to supplement the existing PAR test database with performance data under conditions of interest to U.S. plants. Preliminary findings from the EPRI/EdF PAR model test program are included. Successful completion of this test program and confirmatory tests being sponsored by the U. S. NRC are expected to pave the way for use of PARs in ALWRs and operating plants. (author)

  19. Toxic, antimicrobial and hemagglutinating activities of the purple fluid of the sea hare Aplysia dactylomela Rang, 1828

    Directory of Open Access Journals (Sweden)

    Melo V.M.M.

    1998-01-01

    Full Text Available The antimicrobial, hemagglutinating and toxic activities of the purple fluid of the sea hare Aplysia dactylomela are described. Intact or dialyzed purple fluid inhibited the growth of species of Gram-positive and Gram-negative bacteria and the action was not bactericidal but bacteriostatic. The active factor or factors were heat labile and sensitive to extreme pH values. The fluid preferentially agglutinated rabbit erythrocytes and, to a lesser extent, human blood cells, and this activity was inhibited by the glycoprotein fetuin, a fact suggesting the presence of a lectin. The fluid was also toxic to brine shrimp nauplii (LD50 141.25 µg protein/ml and to mice injected intraperitoneally (LD50 201.8 ± 8.6 mg protein/kg, in a dose-dependent fashion. These toxic activities were abolished when the fluid was heated. Taken together, the data suggest that the activities of the purple fluid are due primarily to substance(s of a protein nature which may be involved in the chemical defense mechanism of this sea hare.

  20. Comparison of a Recombinant-antigen Enzyme Immunoassay with Treponema pallidum Hemagglutination Test for Serological Confirmation of Syphilis

    Directory of Open Access Journals (Sweden)

    Rodríguez Islay

    2002-01-01

    Full Text Available A recombinant-antigen enzyme immunoassay (EIA, BioSCREEN TM anti-Treponema pallidum, was compared favorably with the T. pallidum hemagglutination test, in the detection of specific antibodies in different groups of sera from patients with primary (n = 38, secondary (n = 10, early latent (n = 28 and congenital syphilis (n = 2, patients with leptospirosis ( n= 8, infectious mononucleosis (n = 7, hepatitis (n = 9, diabetes mellitus (n = 11, rheumatoid arthritis (n = 13, leprosy (n = 11, tuberculosis (n = 9, HIV/Aids ( n= 12, systemic lupus erythematosus (n = 4, rheumatic fever (n = 3, old-persons (n = 9, pregnant women (n = 29 and blood donors (n = 164. The coincidence between them was 95.1%. The sensitivity and specificity of the EIA were 93.3% and 95.5%, respectively. Fifteen serum specimens belonging to old-persons, pregnant women, blood donors, and patients with human leptospirosis, hepatitis, diabetes mellitus, tuberculosis and rheumatic fever gave false-positive results by Venereal Disease Research Laboratory and/or Rapid Plasma Reagin. The EIA can be used as alternative method for the serological confirmation of syphilis.

  1. Reprogramming of somatic cells induced by fusion of embryonic stem cells using hemagglutinating virus of Japan envelope (HVJ-E)

    International Nuclear Information System (INIS)

    Yue, Xiao-shan; Fujishiro, Masako; Toyoda, Masashi; Akaike, Toshihiro; Ito, Yoshihiro

    2010-01-01

    In this research, hemagglutinating virus of Japan envelope (HVJ-E) was used to reprogram somatic cells by fusion with mouse embryonic stem (ES) cells. Neomycin-resistant mouse embryonic fibroblasts (MEFs) were used as somatic cells. Nanog-overexpressing puromycin-resistant EB3 cells were used as mouse ES cells. These two cells were fused by exposing to HVJ-E and the generated fusion cells were selected by puromycin and G418 to get the stable fusion cell line. The fusion cells form colonies in feeder-free culture system. Microsatellite analysis of the fusion cells showed that they possessed genes from both ES cells and fibroblasts. The fusion cells were tetraploid, had alkali phosphatase activity, and expressed stem cell marker genes such as Pou5f1, Nanog, and Sox2, but not the fibroblast cell marker genes such as Col1a1 and Col1a2. The pluripotency of fusion cells was confirmed by their expression of marker genes for all the three germ layers after differentiation induction, and by their ability to form teratoma which contained all the three primary layers. Our results show that HVJ-E can be used as a fusion reagent for reprogramming of somatic cells.

  2. Reprogramming of somatic cells induced by fusion of embryonic stem cells using hemagglutinating virus of Japan envelope (HVJ-E)

    Energy Technology Data Exchange (ETDEWEB)

    Yue, Xiao-shan [Nano Medical Engineering Laboratory, RIKEN Advanced Science Institute, 2-1 Hirosawa, Wako-shi, Saitama 351-0198 (Japan); Department of Biomolecular Engineering, Graduate School of Bioscience and Technology, Tokyo Institute of Technology, Nagatsuta-cho, Midori-ku, Yokohama-shi, Kanagawa 226-8501 (Japan); Fujishiro, Masako [Nano Medical Engineering Laboratory, RIKEN Advanced Science Institute, 2-1 Hirosawa, Wako-shi, Saitama 351-0198 (Japan); Toyoda, Masashi [Department of Reproductive Biology, National Institute for Child Health and Development, 2-10-1, Okura, Setagaya-ku, Tokyo 157-8535 (Japan); Akaike, Toshihiro [Department of Biomolecular Engineering, Graduate School of Bioscience and Technology, Tokyo Institute of Technology, Nagatsuta-cho, Midori-ku, Yokohama-shi, Kanagawa 226-8501 (Japan); Ito, Yoshihiro, E-mail: y-ito@riken.jp [Nano Medical Engineering Laboratory, RIKEN Advanced Science Institute, 2-1 Hirosawa, Wako-shi, Saitama 351-0198 (Japan); Department of Biomolecular Engineering, Graduate School of Bioscience and Technology, Tokyo Institute of Technology, Nagatsuta-cho, Midori-ku, Yokohama-shi, Kanagawa 226-8501 (Japan)

    2010-04-16

    In this research, hemagglutinating virus of Japan envelope (HVJ-E) was used to reprogram somatic cells by fusion with mouse embryonic stem (ES) cells. Neomycin-resistant mouse embryonic fibroblasts (MEFs) were used as somatic cells. Nanog-overexpressing puromycin-resistant EB3 cells were used as mouse ES cells. These two cells were fused by exposing to HVJ-E and the generated fusion cells were selected by puromycin and G418 to get the stable fusion cell line. The fusion cells form colonies in feeder-free culture system. Microsatellite analysis of the fusion cells showed that they possessed genes from both ES cells and fibroblasts. The fusion cells were tetraploid, had alkali phosphatase activity, and expressed stem cell marker genes such as Pou5f1, Nanog, and Sox2, but not the fibroblast cell marker genes such as Col1a1 and Col1a2. The pluripotency of fusion cells was confirmed by their expression of marker genes for all the three germ layers after differentiation induction, and by their ability to form teratoma which contained all the three primary layers. Our results show that HVJ-E can be used as a fusion reagent for reprogramming of somatic cells.

  3. [EIA-IgG antibody measles prevention level estimated from measles neutralizing, particle agglutination and hemagglutination-inhibition antibody titer].

    Science.gov (United States)

    Takayama, Naohide; Saika, Shizuko; Ichinohe, Sadato

    2009-09-01

    Measles hemagglutination inhibition (HI) antibody titer, widely used in clinical practice to simply and easily determine the measles immunity level has, in recent years, been increasingly replaced by measles IgG-antibody titer determined by enzyme-immunoassay (EIA). HI antibody titer appears to reflect this protective level, because HI measures the antibody against H protein required for the measles virus to adhere to host cells. EIA-IgG antibody titer does not correlate with the protective level, similar to particle agglutination (PA) titer, because EIA measures different antibodies, including those unrelated to measles protection. After determining HI, PA, neutralizing test (NT) results, and EIA-IgG antibody titer for individual specimens, we compared EIA-IgG antibody titer obtained using an EIA-Kit (Denka Seiken) to HI, PA, and NT titer with the following results: (1) Subjects with EIA-IgG titer of > or = 12.0 may be protected against measles: (2) Subjects with EIA-IgG titer of 4.0 to 8.0 appear to be protected insufficiently requiring a booster dose against measles: (3) Subjects with EIA-IgG titer of 8.0 to 12.0 may benefit from booster vaccination.

  4. Hemagglutinating virus of Japan envelope (HVJ-E) can enhance the immune responses of swine immunized with killed PRRSV vaccine

    Energy Technology Data Exchange (ETDEWEB)

    Dai, Zhihong [State Key Laboratory of Agrobiotechnology, College of Veterinary Medicine, China Agricultural University, Beijing 100094 (China); China Institute of Veterinary Drug Control, Beijing 100081 (China); Zhang, Quan [College of Veterinary Medicine, Yangzhou University, Yangzhou 225009 (China); Wang, Zaishi [China Institute of Veterinary Drug Control, Beijing 100081 (China); Zhang, Zhongqiu [State Key Laboratory of Agrobiotechnology, College of Veterinary Medicine, China Agricultural University, Beijing 100094 (China); Veterinary Bureau, Ministry of Agriculture of the People' s Republic of China, Beijing 100125 (China); Guo, Pengju [Institute of Veterinary Medicine, Guangdong Academy of Agricultural Sciences, Guangdong 510640 (China); Zhao, Deming, E-mail: zhaodm@cau.edu.cn [State Key Laboratory of Agrobiotechnology, College of Veterinary Medicine, China Agricultural University, Beijing 100094 (China)

    2011-11-11

    Highlights: Black-Right-Pointing-Pointer We investigated the immunoadjuvant effects of HVJ-E on killed PRRSV vaccine. Black-Right-Pointing-Pointer HVJ-E enhanced the humoral and cellular responses of the piglets to PRRSV. Black-Right-Pointing-Pointer It is suggested that HVJ-E could be developed as a new-type adjuvant for mammals. -- Abstract: Porcine reproductive and respiratory syndrome virus (PRRSV) is an economically detrimental pig pathogen that causes significant losses for the pig industry. The immunostimulatory effects of hemagglutinating virus of Japan envelope (HVJ-E) in cancer therapy and the adjuvant efficacy of HVJ-E have been previously evaluated. The objective of this study was to investigate the adjuvant effects of HVJ-E on immunization with killed PRRSV vaccine, and to evaluate the protective effects of this immunization strategy against virulent PRRSV infection in piglets. Next, the PRRSV-specific antibody response, lymphocyte proliferation, PRRSV-specific IL-2, IL-10 and IFN-{gamma} production, and the overall protection efficacy were evaluated to assess the immune responses of the piglets. The results showed that the piglets inoculated simultaneously with killed PRRSV vaccine and HVJ-E had a significantly stronger immune response than those inoculated with killed PRRSV vaccine alone. Our results suggest that HVJ-E could be employed as an effective adjuvant to enhance the humoral and cellular responses of piglets to PRRSV.

  5. La pelade par plaques

    Science.gov (United States)

    Spano, Frank; Donovan, Jeff C.

    2015-01-01

    Résumé Objectif Présenter aux médecins de famille des renseignements de base pour faire comprendre l’épidémiologie, la pathogenèse, l’histologie et l’approche clinique au diagnostic de la pelade par plaques. Sources des données Une recension a été effectuée dans PubMed pour trouver des articles pertinents concernant la pathogenèse, le diagnostic et le pronostic de la pelade par plaques. Message principal La pelade par plaques est une forme de perte pileuse auto-immune dont la prévalence durant une vie est d’environ 2 %. Des antécédents personnels ou familiaux de troubles auto-immuns concomitants, comme le vitiligo ou une maladie de la thyroïde, peuvent être observés dans un petit sous-groupe de patients. Le diagnostic peut souvent être posé de manière clinique en se fondant sur la perte de cheveux non cicatricielle et circulaire caractéristique, accompagnée de cheveux en « point d’exclamation » en périphérie chez ceux dont le problème en est aux premiers stades. Le diagnostic des cas plus complexes ou des présentations inhabituelles peut être facilité par une biopsie et un examen histologique. Le pronostic varie largement et de mauvais résultats sont associés à une apparition à un âge précoce, une perte importante, la variante ophiasis, des changements aux ongles, des antécédents familiaux ou des troubles auto-immuns concomitants. Conclusion La pelade par plaques est une forme auto-immune de perte de cheveux périodiquement observée en soins primaires. Les médecins de famille sont bien placés pour identifier la pelade par plaques, déterminer la gravité de la maladie et poser le diagnostic différentiel approprié. De plus, ils sont en mesure de renseigner leurs patients à propos de l’évolution clinique de la maladie ainsi que du pronostic général selon le sous-type de patients.

  6. Compositional properties of passivity

    NARCIS (Netherlands)

    Kerber, Florian; van der Schaft, Arjan

    2011-01-01

    The classical passivity theorem states that the negative feedback interconnection of passive systems is again passive. The converse statement, - passivity of the interconnected system implies passivity of the subsystems -, turns out to be equally valid. This result implies that among all feasible

  7. Non-hemagglutinating flaviviruses: molecular mechanisms for the emergence of new strains via adaptation to European ticks.

    Directory of Open Access Journals (Sweden)

    Maxim A Khasnatinov

    2009-10-01

    Full Text Available Tick-borne encephalitis virus (TBEV causes human epidemics across Eurasia. Clinical manifestations range from inapparent infections and fevers to fatal encephalitis but the factors that determine disease severity are currently undefined. TBEV is characteristically a hemagglutinating (HA virus; the ability to agglutinate erythrocytes tentatively reflects virion receptor/fusion activity. However, for the past few years many atypical HA-deficient strains have been isolated from patients and also from the natural European host tick, Ixodes persulcatus. By analysing the sequences of HA-deficient strains we have identified 3 unique amino acid substitutions (D67G, E122G or D277A in the envelope protein, each of which increases the net charge and hydrophobicity of the virion surface. Therefore, we genetically engineered virus mutants each containing one of these 3 substitutions; they all exhibited HA-deficiency. Unexpectedly, each genetically modified non-HA virus demonstrated increased TBEV reproduction in feeding Ixodes ricinus, not the recognised tick host for these strains. Moreover, virus transmission efficiency between infected and uninfected ticks co-feeding on mice was also intensified by each substitution. Retrospectively, the mutation D67G was identified in viruses isolated from patients with encephalitis. We propose that the emergence of atypical Siberian HA-deficient TBEV strains in Europe is linked to their molecular adaptation to local ticks. This process appears to be driven by the selection of single mutations that change the virion surface thus enhancing receptor/fusion function essential for TBEV entry into the unfamiliar tick species. As the consequence of this adaptive mutagenesis, some of these mutations also appear to enhance the ability of TBEV to cross the human blood-brain barrier, a likely explanation for fatal encephalitis. Future research will reveal if these emerging Siberian TBEV strains continue to disperse westwards

  8. Consecutive natural influenza a virus infections in sentinel mallards in the evident absence of subtype-specific hemagglutination inhibiting antibodies.

    Science.gov (United States)

    Globig, A; Fereidouni, S R; Harder, T C; Grund, C; Beer, M; Mettenleiter, T C; Starick, E

    2013-10-01

    Dabbling ducks, particularly Mallards (Anas platyrhynchos) have been frequently and consistently reported to play a pivotal role as a reservoir of low pathogenic avian influenza viruses (AIV). From October 2006 to November 2008, hand-raised Mallard ducks kept at a pond in an avifaunistically rich area of Southern Germany served as sentinel birds in the AIV surveillance programme in Germany. The pond was regularly visited by several species of dabbling ducks. A flock of sentinel birds, consisting of the same 16 individual birds during the whole study period, was regularly tested virologically and serologically for AIV infections. Swab samples were screened by RT-qPCR and, if positive, virus was isolated in embryonated chicken eggs. Serum samples were tested by the use of competitive ELISA and hemagglutinin inhibition (HI) assay. Sequences of full-length hemagglutinin (HA) and neuraminidase (NA) genes were phylogenetically analysed. Four episodes of infections with Eurasian-type AIV occurred in August (H6N8), October/November (H3N2, H2N3) 2007, in January (H3N2) and September (H3N8) 2008. The HA and NA genes of the H3N2 viruses of October 2007 and January 2008 were almost identical rendering the possibility of a re-introduction of that virus from the environment of the sentinel flock highly likely. The HA of the H3N8 virus of September 2008 belonged to a different cluster. As a correlate of the humoral immune response, titres of nucleocapsid protein-specific antibodies fluctuated in correlation with the course of AIV infection episodes. However, no specific systemic response of hemagglutination inhibiting antibodies could be demonstrated even if homologous viral antigens were used. Besides being useful as early indicators for the circulation of influenza viruses in a specific region, the sentinel ducks also contributed to gaining insights into the ecobiology of AIV infection in aquatic wild birds. © 2012 Blackwell Verlag GmbH.

  9. suPAR

    DEFF Research Database (Denmark)

    Eugen-Olsen, Jesper; Giamarellos-Bourboulis, Evangelos J

    2015-01-01

    Investigation of biomarkers that can promptly predict unfavourable outcome of critically illness is an emerging necessity taking into consideration the need for early intervention, the shortage of available beds in intensive care units and the considerable cost of hospitalisation. The most...... promising biomarker is soluble urokinase-type plasminogen activator receptor (suPAR). Three studies in large populations of critically ill patients and patients admitted to the emergency department have shown that concentrations >12ng/mL can safely predict unfavourable outcome. This review presents...

  10. Parálisis cerebral :

    OpenAIRE

    Cabrero Izquierdo, María del Carmen

    2012-01-01

    Se aborda el tema de la parálisis cerebral definiendo qué es, clasificando los tipos de parálisis dependiendo de la afectación y las características principales. Se explican algunos de sus tratamientos, se dan sistemas alternativos y/o aumentativos de comunicación para un alumno con PC (parálisis cerebral).

  11. Passive solar technology

    Energy Technology Data Exchange (ETDEWEB)

    Watson, D

    1981-04-01

    The present status of passive solar technology is summarized, including passive solar heating, cooling and daylighting. The key roles of the passive solar system designer and of innovation in the building industry are described. After definitions of passive design and a summary of passive design principles are given, performance and costs of passive solar technology are discussed. Passive energy design concepts or methods are then considered in the context of the overall process by which building decisions are made to achieve the integration of new techniques into conventional design. (LEW).

  12. Passive acoustic monitoring of bed load for fluvial applications

    Science.gov (United States)

    The sediment transported as bed load in streams and rivers is notoriously difficult to monitor cheaply and accurately. Passive acoustic methods are relatively simple, inexpensive, and provide spatial integration along with high temporal resolution. In 1963 work began on monitoring emissions from par...

  13. Fundamental studies of passivity and passivity breakdown

    International Nuclear Information System (INIS)

    Macdonald, D.D.; Urquidi-Macdonald, M.; Song, H.; Biaggio-Rocha, S.; Searson, P.

    1991-11-01

    This report summarizes the findings of our fundamental research program on passivity and passivity breakdown. During the past three and one half years in this program (including the three year incrementally-funded grant prior to the present grant), we developed and experimentally tested various physical models for the growth and breakdown of passive films on metal surfaces. These models belong to a general class termed ''point defects models'' (PDMs), in which the growth and breakdown of passive films are described in terms of the movement of anion and cation vacancies

  14. Immunizations: Active vs. Passive

    Science.gov (United States)

    ... Issues Health Issues Health Issues Conditions Injuries & Emergencies Vaccine Preventable Diseases ... Children > Safety & Prevention > Immunizations > Immunizations: Active vs. Passive Safety & ...

  15. Hydrogenation of passivated contacts

    Energy Technology Data Exchange (ETDEWEB)

    Nemeth, William; Yuan, Hao-Chih; LaSalvia, Vincenzo; Stradins, Pauls; Page, Matthew R.

    2018-03-06

    Methods of hydrogenation of passivated contacts using materials having hydrogen impurities are provided. An example method includes applying, to a passivated contact, a layer of a material, the material containing hydrogen impurities. The method further includes subsequently annealing the material and subsequently removing the material from the passivated contact.

  16. Elusloom lennukiga puhkusele / Inge Parring

    Index Scriptorium Estoniae

    Parring, Inge

    2003-01-01

    Ilmunud ka: Delovõje Vedomosti 1. okt. lk. 13. Air Cargo Estonia/ACE Logisticsi müügijuht Inge Parring tutvustab elusloomade transpordivõimalusi. Vt. samas: Loomade transportimiseks vajalikud dokumendid

  17. CFD Analysis of Passive Autocatalytic Recombiner

    Directory of Open Access Journals (Sweden)

    B. Gera

    2011-01-01

    Full Text Available In water-cooled nuclear power reactors, significant quantities of hydrogen could be produced following a postulated loss-of-coolant accident (LOCA along with nonavailability of emergency core cooling system (ECCS. Passive autocatalytic recombiners (PAR are implemented in the containment of water-cooled power reactors to mitigate the risk of hydrogen combustion. In the presence of hydrogen with available oxygen, a catalytic reaction occurs spontaneously at the catalyst surfaces below conventional ignition concentration limits and temperature and even in presence of steam. Heat of reaction produces natural convection flow through the enclosure and promotes mixing in the containment. For the assessment of the PAR performance in terms of maximum temperature of catalyst surface and outlet hydrogen concentration an in-house 3D CFD model has been developed. The code has been used to study the mechanism of catalytic recombination and has been tested for two literature-quoted experiments.

  18. Par Pond vegetation status 1996

    International Nuclear Information System (INIS)

    Mackey, H.E. Jr.; Riley, R.S.

    1996-12-01

    The water level of Par Pond was lowered approximately 20 feet in mid-1991 in order to protect downstream residents from possible dam failure suggested by subsidence on the downstream slope of the dam and to repair the dam. This lowering exposed both emergent and nonemergent macrophyte beds to drying conditions resulting in extensive losses. A survey of the newly emergent, shoreline aquatic plant communities of Par Pond began in June 1995, three months after the refilling of Par Pond to approximately 200 feet above mean sea level. These surveys continued in July, September, and late October, 1995, and into the early spring and late summer of 1996. Communities similar to the pre-drawdown, Par Pond aquatic plant communities continue to become re-established. Emergent beds of maidencane, lotus, waterlily, watershield, and Pontederia are extensive and well developed. Measures of percent cover, width of beds, and estimates of area of coverage with satellite data indicate regrowth within two years of from 40 to 60% of levels prior to the draw down. Cattail occurrence continued to increase during the summer of 1996, especially in the former warm arm of Par Pond, but large beds common to Par Pond prior to the draw down still have not formed. Lotus has invaded and occupies many of the areas formerly dominated by cattail beds. To track the continued development of macrophytes in Par Pond, future surveys through the summer and early fall of 1997, along with the evaluation of satellite data to map the extent of the macrophyte beds of Par Pond, are planned

  19. Formation of SiN{sub x}:H by PECVD: optimization of the optical, bulk passivation and structural properties for photovoltaic applications; Elaboration de SiN{sub x}:H par PECVD: optimisation des proprietes optiques, passivantes et structurales pour applications photovoltaiques

    Energy Technology Data Exchange (ETDEWEB)

    Lelievre, J.F

    2007-04-15

    The hydrogenated silicon nitride SiNx:H is widely used as antireflection coating and passivation layer in the manufacture of silicon photovoltaic cells. The aim of this work was to implement a low frequency (440 kHz) PECVD reactor and to characterize the obtained SiN layers. After having determined the parameters of the optimal deposition, the physico-chemical structure of the layers has been studied. The optical properties have been studied with the aim to improve the antireflection coating of the photovoltaic cells. The surface and bulk passivation properties, induced by the SiN layer in terms of its stoichiometry, have been analyzed and have revealed the excellent passivating efficiency of this material. At last, have been studied the formation conditions of the silicon nano-crystals in the SiN matrix. (O.M.)

  20. Comparison of indirect hemagglutination and 51Chromium release tests for detection of herpes simplex virus types 1 and 2 antibodies in patients with recurrent herpes infections

    International Nuclear Information System (INIS)

    Kesavalu, L.; Seth, P.

    1980-01-01

    Indirect hemagglutination and 51 Cr release tests (IHAT and 51-CRT respectively) were compared in patients with recurrent herpes simplex virus (HSV) infections from whom HSV-1 or HSV-2 was isolated. Both tests were equally sensitive and specific in detecting HSV antibodies. However, IHAT was more specific in detecting homologous HSV antibody response in patients with recurrent HSV-2 infections. Past infections with HSV-1 in the patients with dual infections were detected by determining HSV-type specific antibodies by inhibition of IHAT. Cross absorption studies showed that the antibody reactivity measured by the two tests was qualitatively and quantitatively different. Nevertheless, IHAT has been found to be more appropriate test for seroepidemiologic studies of HSV-2 infections because of its specificity, rapidity and less cost, whereas, 51-CRT appears to measure antibodies against recent and more predominant type of infecting HSV. (Author)

  1. Comparison of the Hemagglutination Inhibition Test and IgG ELISA in Categorizing Primary and Secondary Dengue Infections Based on the Plaque Reduction Neutralization Test

    Directory of Open Access Journals (Sweden)

    Nurhayati Lukman

    2016-01-01

    Full Text Available Secondary dengue infection by heterotypic serotypes is associated with severe manifestations of disease, that is, dengue hemorrhagic fever (DHF and dengue shock syndrome (DSS. The World Health Organization (WHO has recommended criteria based on the hemagglutination inhibition (HI test to distinguish between primary and secondary dengue infections. Since the HI test has practical limitations and disadvantages, we evaluated the accuracy of WHO HI criteria and compared it with criteria based on an IgG enzyme-linked immunosorbent assay (ELISA using a plaque reduction neutralization test (PRNT as the gold standard. Both WHO HI criteria and IgG ELISA criteria performed strongly (16/16 in determining primary infection. However, to determine secondary infection, the IgG ELISA criteria performed better (72/73 compared to the WHO HI criteria (23/73.

  2. Vote par sondage uniforme incorruptible

    OpenAIRE

    Blanchard , Nicolas

    2016-01-01

    International audience; Introduit en 2012 par David Chaum, le vote par sondage uniforme (random-sample voting) est un protocole de vote basé sur un choix d'une sous-population représentative , permettant de limiter les coûts tout en ayant de nombreux avantages, principalement lorsqu'il est couplé a d'autres techniques comme ThreeBallot. Nous analysons un problème de corruptibilité potentielle où les votants peuvent vendre leur vote au plus offrant et proposons une variation du protocole reméd...

  3. Passive magnetic bearing configurations

    Science.gov (United States)

    Post, Richard F [Walnut Creek, CA

    2011-01-25

    A journal bearing provides vertical and radial stability to a rotor of a passive magnetic bearing system when the rotor is not rotating and when it is rotating. In the passive magnetic bearing system, the rotor has a vertical axis of rotation. Without the journal bearing, the rotor is vertically and radially unstable when stationary, and is vertically stable and radially unstable when rotating.

  4. Passive solar construction handbook

    Energy Technology Data Exchange (ETDEWEB)

    Levy, E.; Evans, D.; Gardstein, C.

    1981-08-01

    Many of the basic elements of passive solar design are reviewed. The unique design constraints presented in passive homes are introduced and many of the salient issues influencing design decisions are described briefly. Passive solar construction is described for each passive system type: direct gain, thermal storage wall, attached sunspace, thermal storage roof, and convective loop. For each system type, important design and construction issues are discussed and case studies illustrating designed and built examples of the system type are presented. Construction details are given and construction and thermal performance information is given for the materials used in collector components, storage components, and control components. Included are glazing materials, framing systems, caulking and sealants, concrete masonry, concrete, brick, shading, reflectors, and insulators. The Load Collector Ratio method for estimating passive system performance is appended, and other analysis methods are briefly summarized. (LEW)

  5. Passivity and Evolutionary Game Dynamics

    KAUST Repository

    Park, Shinkyu; Shamma, Jeff S.; Martins, Nuno C.

    2018-01-01

    This paper investigates an energy conservation and dissipation -- passivity -- aspect of dynamic models in evolutionary game theory. We define a notion of passivity using the state-space representation of the models, and we devise systematic methods to examine passivity and to identify properties of passive dynamic models. Based on the methods, we describe how passivity is connected to stability in population games and illustrate stability of passive dynamic models using numerical simulations.

  6. Passivity and Evolutionary Game Dynamics

    KAUST Repository

    Park, Shinkyu

    2018-03-21

    This paper investigates an energy conservation and dissipation -- passivity -- aspect of dynamic models in evolutionary game theory. We define a notion of passivity using the state-space representation of the models, and we devise systematic methods to examine passivity and to identify properties of passive dynamic models. Based on the methods, we describe how passivity is connected to stability in population games and illustrate stability of passive dynamic models using numerical simulations.

  7. Par Pond Fish, Water, and Sediment Chemistry

    Energy Technology Data Exchange (ETDEWEB)

    Paller, M.H. [Westinghouse Savannah River Company, AIKEN, SC (United States); Wike, L.D.

    1996-06-01

    The objectives of this report are to describe the Par Pond fish community and the impact of the drawdown and refill on the community, describe contaminant levels in Par Pond fish, sediments, and water and indicate how contaminant concentrations and distributions were affected by the drawdown and refill, and predict possible effects of future water level fluctuations in Par Pond.

  8. Par Pond Fish, Water, and Sediment Chemistry

    International Nuclear Information System (INIS)

    Paller, M.H.; Wike, L.D.

    1996-06-01

    The objectives of this report are to describe the Par Pond fish community and the impact of the drawdown and refill on the community, describe contaminant levels in Par Pond fish, sediments, and water and indicate how contaminant concentrations and distributions were affected by the drawdown and refill, and predict possible effects of future water level fluctuations in Par Pond

  9. Aktiv kontra passiv forvaltning

    DEFF Research Database (Denmark)

    Bechmann, Ken L.; Pedersen, Lasse Heje

    2017-01-01

    Fordele og ulemper ved aktiv og passiv forvaltning har fået fornyet opmærksomhed blandt andet i forbindelse med den forestående implementering af MiFID II. Som bidrag til denne diskussion indeholder dette nummer af Finans/Invest tre artikler, der behandler aktiv og passiv forvaltning fra...... forskellige vinkler. Denne leder forklarer, hvorfor valget mellem aktiv og passiv forvaltning er mere kompliceret, end hvad man kunne tro ved første øjekast, og konkluderer, at der vil være plads til - og behov for - begge typer forvaltning....

  10. Most energetic passive states.

    Science.gov (United States)

    Perarnau-Llobet, Martí; Hovhannisyan, Karen V; Huber, Marcus; Skrzypczyk, Paul; Tura, Jordi; Acín, Antonio

    2015-10-01

    Passive states are defined as those states that do not allow for work extraction in a cyclic (unitary) process. Within the set of passive states, thermal states are the most stable ones: they maximize the entropy for a given energy, and similarly they minimize the energy for a given entropy. Here we find the passive states lying in the other extreme, i.e., those that maximize the energy for a given entropy, which we show also minimize the entropy when the energy is fixed. These extremal properties make these states useful to obtain fundamental bounds for the thermodynamics of finite-dimensional quantum systems, which we show in several scenarios.

  11. A pseudovirus-based hemagglutination-inhibition assay as a rapid, highly sensitive, and specific assay for detecting avian influenza A (H7N9 antibodies

    Directory of Open Access Journals (Sweden)

    Anli Zhang

    2015-06-01

    Full Text Available Background Increased surveillance of avian-origin influenza A (H7N9 virus infection is critical to assess the risk of new outbreaks in China. A high-throughput assay with a good safety profile, sensitivity, and specificity is urgently needed. Methods We used a hemagglutination-inhibition (HI assay based on an H7N9-enveloped pseudovirus to assess serum neutralization antibodies level in 40 H7N9 positive sera and 40 H7N9 negative sera and compared the efficacy of the assay with traditional HI test and micro-neutralization (MN test. Results Spearman’s rank correlation coefficient analysis showed pseudovirus HI (PHI titers correlated well with both HI titers and MN titers. Receiver operating characteristic (ROC curves test revealed using a PHI cut-off titer of 10, the sensitivity and specificity reached 1.0. Conclusions PHI can be used in H7N9-related serological studies. This assay is high-throughput, very sensitive and specific, and cost effective.

  12. Techniques for active passivation

    Science.gov (United States)

    Roscioli, Joseph R.; Herndon, Scott C.; Nelson, Jr., David D.

    2016-12-20

    In one embodiment, active (continuous or intermittent) passivation may be employed to prevent interaction of sticky molecules with interfaces inside of an instrument (e.g., an infrared absorption spectrometer) and thereby improve response time. A passivation species may be continuously or intermittently applied to an inlet of the instrument while a sample gas stream is being applied. The passivation species may have a highly polar functional group that strongly binds to either water or polar groups of the interfaces, and once bound presents a non-polar group to the gas phase in order to prevent further binding of polar molecules. The instrument may be actively used to detect the sticky molecules while the passivation species is being applied.

  13. Passive radon daughter dosimeters

    International Nuclear Information System (INIS)

    McElroy, R.G.C.; Johnson, J.R.

    1986-03-01

    On the basis of an extensive review of the recent literature concerning passive radon daughter dosimeters, we have reached the following conclusions: 1) Passive dosimeters for measuring radon are available and reliable. 2) There does not presently exist an acceptable passive dosimeter for radon daughters. There is little if any hope for the development of such a device in the foreseeable future. 3) We are pessimistic about the potential of 'semi-passive dosimeters' but are less firm about stating categorically that these devices cannot be developed into a useful radon daughter dosimeter. This report documents and justifies these conclusions. It does not address the question of the worker's acceptance of these devices because at the present time, no device is sufficiently advanced for this question to be meaningful. 118 refs

  14. Passive Mixing inside Microdroplets

    Directory of Open Access Journals (Sweden)

    Chengmin Chen

    2018-04-01

    Full Text Available Droplet-based micromixers are essential units in many microfluidic devices for widespread applications, such as diagnostics and synthesis. The mixers can be either passive or active. When compared to active methods, the passive mixer is widely used because it does not require extra energy input apart from the pump drive. In recent years, several passive droplet-based mixers were developed, where mixing was characterized by both experiments and simulation. A unified physical understanding of both experimental processes and simulation models is beneficial for effectively developing new and efficient mixing techniques. This review covers the state-of-the-art passive droplet-based micromixers in microfluidics, which mainly focuses on three aspects: (1 Mixing parameters and analysis method; (2 Typical mixing element designs and the mixing characters in experiments; and, (3 Comprehensive introduction of numerical models used in microfluidic flow and diffusion.

  15. CANDU passive shutdown systems

    Energy Technology Data Exchange (ETDEWEB)

    Hart, R S; Olmstead, R A [AECL CANDU, Sheridan Park Research Community, Mississauga, ON (Canada)

    1996-12-01

    CANDU incorporates two diverse, passive shutdown systems, independent of each other and from the reactor regulating system. Both shutdown systems function in the low pressure, low temperature, moderator which surrounds the fuel channels. The shutdown systems are functionally different, physically separate, and passive since the driving force for SDS1 is gravity and the driving force for SDS2 is stored energy. The physics of the reactor core itself ensures a degree of passive safety in that the relatively long prompt neutron generation time inherent in the design of CANDU reactors tend to retard power excursions and reduces the speed required for shutdown action, even for large postulated reactivity increases. All passive systems include a number of active components or initiators. Hence, an important aspect of passive systems is the inclusion of fail safe (activated by active component failure) operation. The mechanisms that achieve the fail safe action should be passive. Consequently the passive performance of the CANDU shutdown systems extends beyond their basic modes of operation to include fail safe operation based on natural phenomenon or stored energy. For example, loss of power to the SDS1 clutches results in the drop of the shutdown rods by gravity, loss of power or instrument air to the injection valves of SDS2 results in valve opening via spring action, and rigorous self checking of logic, data and timing by the shutdown systems computers assures a fail safe reactor trip through the collapse of a fluctuating magnetic field or the discharge of a capacitor. Event statistics from operating CANDU stations indicate a significant decrease in protection system faults that could lead to loss of production and elimination of protection system faults that could lead to loss of protection. This paper provides a comprehensive description of the passive shutdown systems employed by CANDU. (author). 4 figs, 3 tabs.

  16. Directed and persistent movement arises from mechanochemistry of the ParA/ParB system.

    Science.gov (United States)

    Hu, Longhua; Vecchiarelli, Anthony G; Mizuuchi, Kiyoshi; Neuman, Keir C; Liu, Jian

    2015-12-22

    The segregation of DNA before cell division is essential for faithful genetic inheritance. In many bacteria, segregation of low-copy number plasmids involves an active partition system composed of a nonspecific DNA-binding ATPase, ParA, and its stimulator protein ParB. The ParA/ParB system drives directed and persistent movement of DNA cargo both in vivo and in vitro. Filament-based models akin to actin/microtubule-driven motility were proposed for plasmid segregation mediated by ParA. Recent experiments challenge this view and suggest that ParA/ParB system motility is driven by a diffusion ratchet mechanism in which ParB-coated plasmid both creates and follows a ParA gradient on the nucleoid surface. However, the detailed mechanism of ParA/ParB-mediated directed and persistent movement remains unknown. Here, we develop a theoretical model describing ParA/ParB-mediated motility. We show that the ParA/ParB system can work as a Brownian ratchet, which effectively couples the ATPase-dependent cycling of ParA-nucleoid affinity to the motion of the ParB-bound cargo. Paradoxically, this resulting processive motion relies on quenching diffusive plasmid motion through a large number of transient ParA/ParB-mediated tethers to the nucleoid surface. Our work thus sheds light on an emergent phenomenon in which nonmotor proteins work collectively via mechanochemical coupling to propel cargos-an ingenious solution shaped by evolution to cope with the lack of processive motor proteins in bacteria.

  17. Positron Accumulator Ring (PAR) power supply

    International Nuclear Information System (INIS)

    Fathizadeh, M.

    1995-01-01

    The Positron Accumulator Ring (PAR) consists of 8 dipole magnets connected in series. These magnets are energized via one 12-pulse dc power supply. The power supply consists of four phase controlled half-wave wye group converters. Each of the two half-wave converters are connected through an interphase transformer to obtain a full-wave converter with 120 degrees conduction. The input voltage for these two half-wave converters are 180 degrees apart. The two full-wave converters are connected in parallel through a third interphase transformer. This type of connection of the converters not only provides the required output current, it also improves the input power factor of the power supply. The output of the wye group converters is filtered through a passive L-R-C filter to reduce the ripple content of the output current. At low current values of the power supply the current ripple is high, thus a large filter is needed, which adds to the cost of the power supply, however at high output current levels, the current ripple is less severe. The large size of the filter can be reduced by adding an anti-parallel rectifier diode(D1) to the output of the power supply. A freewheeling diode(D2) is connected before the choke to circulate the current once the power supply is turned off. In order to measure the current in the magnet a high precision, low drift, zero flux current transductor is used. This transductor senses the magnet current which provides a feedback signal to control the gating of the converter's thyristors. A true 14 bit Digital to Analog Converter (DAC) is programmed by the control computer for the required current value, providing a reference for the current regulator. Fast correction of the line transients is provided by a relatively fast voltage loop controlled by a high gain slow response current loop

  18. Passive House Solutions

    Energy Technology Data Exchange (ETDEWEB)

    Strom, I.; Joosten, L.; Boonstra, C. [DHV Sustainability Consultants, Eindhoiven (Netherlands)

    2006-05-15

    PEP stands for 'Promotion of European Passive Houses' and is a consortium of European partners, supported by the European Commission, Directorate General for Energy and Transport. In this working paper an overview is given of Passive House solutions. An inventory has been made of Passive House solutions for new build residences applied in each country. Based on this, the most common basic solutions have been identified and described in further detail, including the extent to which solutions are applied in common and best practice and expected barriers for the implementation in each country. An inventory per country is included in the appendix. The analysis of Passive House solutions in partner countries shows high priority with regard to the performance of the thermal envelope, such as high insulation of walls, roofs, floors and windows/ doors, thermal bridge-free construction and air tightness. Due to the required air tightness, special attention must be paid to indoor air quality through proper ventilation. Finally, efficient ((semi-)solar) heating systems for combined space and DHW heating still require a significant amount of attention in most partner countries. Other basic Passive House solutions show a smaller discrepancy with common practice and fewer barriers have been encountered in partner countries. In the next section, the general barriers in partner countries have been inventoried. For each type of barrier a suggested approach has been given. Most frequently encountered barriers in partner countries are: limited know-how; limited contractor skills; and acceptation of Passive Houses in the market. Based on the suggested approaches to overcoming barriers, this means that a great deal of attention must be paid to providing practical information and solutions to building professionals, providing practical training to installers and contractors and communication about the Passive House concept to the market.

  19. Recherche documentaire par titrage automatique

    OpenAIRE

    Lopez , Cédric; Prince , Violaine; Roche , Mathieu

    2011-01-01

    Nous proposons dans cet article un système facilitant la recherche d'information dans un ensemble de documents textuels, basé sur le titrage (et sous-titrage) automatique. Ce dernier peut se révéler crucial, par exemple, dans le cadre de la problématique de l'accessibilité des pages web (norme W3C). Notre processus de titrage automatique consiste à extraire des syntagmes nominaux pertinents dans les textes, pouvant constituer des titres ou sous-titres candidats. Une approche originale combina...

  20. Measure Guideline: Passive Vents

    Energy Technology Data Exchange (ETDEWEB)

    Berger, David [Consortium for Advanced Residential Buildings, Norwalk, CT (United States); Neri, Robin [Consortium for Advanced Residential Buildings, Norwalk, CT (United States)

    2016-02-05

    This document addresses the use of passive vents as a source of outdoor air in multifamily buildings. The challenges associated with implementing passive vents and the factors affecting performance are outlined. A comprehensive design methodology and quantified performance metrics are provided. Two hypothetical design examples are provided to illustrate the process. This document is intended to be useful to designers, decision-makers, and contractors implementing passive ventilation strategies. It is also intended to be a resource for those responsible for setting high-performance building program requirements, especially pertaining to ventilation and outdoor air. To ensure good indoor air quality, a dedicated source of outdoor air is an integral part of high-performance buildings. Presently, there is a lack of guidance pertaining to the design and installation of passive vents, resulting in poor system performance. This report details the criteria necessary for designing, constructing, and testing passive vent systems to enable them to provide consistent and reliable levels of ventilation air from outdoors.

  1. Constructing passive houses

    Energy Technology Data Exchange (ETDEWEB)

    Oehler, S. [Oehler Faigle Archkom Solar Architektur, Bretten (Germany)

    2005-07-01

    Everybody can learn to build energy-efficient. It needs theoretical and practical experience. 1997 we built the first freestanding Passive House in Europe, the Passive House Oehler. There had been a lot of questions, starting with the insecurity, whether the calculation program of the Passive House Institute, the PHPP, is working properly in our case. Nobody knew at that time because nobody tried it out before. It took us a lot of time to find out and every detail of the construction hat to be invented to meet the very high demand of thermal quality. All the following houses needed less time and had fewer open questions, adding one piece of experience with every building. 2002 we realised the biggest Passive House, the office building Energon Ulm with 420 working spaces. In the meantime we have learned a lot like how to produce prefabricated timber elements for the facades, providing good insulation, air tightness and avoiding serious thermal bridges. We have proofed, that any kind of building type can be a Passive House. And with increasing experience the freedom of design and construction is growing. Even the economical efficiency increased. The Energon Ulm is providing a much better indoor climate than any other office building and was build 10 % cheaper than an average German office building. At present the Passive House Standard is the most efficient solution for the user to live in the desired comfort zone between 20 C and 25 C. This zone of individual feeling-well can be described with the term ''operative temperature''. This term is defined by factors like air temperature, radiation temperature of warm and cold surfaces, air speed and humidity. The result of all these factors has to be within 18 C to 25 C without accepting one of the factors getting extreme.

  2. Passive containment system

    International Nuclear Information System (INIS)

    Kleimola, F.W.

    1977-01-01

    Disclosed is a containment system that provides complete protection entirely by passive means for the loss of coolant accident in a nuclear power plant and wherein all stored energy released in the coolant blowdown is contained and absorbed while the nuclear fuel is prevented from over-heating by a high containment back-pressure and a reactor vessel refill system. The primary containment vessel is restored to a high sub-atmospheric pressure within a few minutes after accident initiation and the decay heat is safely transferred to the environment while radiolytic hydrogen is contained by passive means. 20 claims, 14 figures

  3. Wireless passive radiation sensor

    Science.gov (United States)

    Pfeifer, Kent B; Rumpf, Arthur N; Yelton, William G; Limmer, Steven J

    2013-12-03

    A novel measurement technique is employed using surface acoustic wave (SAW) devices, passive RF, and radiation-sensitive films to provide a wireless passive radiation sensor that requires no batteries, outside wiring, or regular maintenance. The sensor is small (<1 cm.sup.2), physically robust, and will operate unattended for decades. In addition, the sensor can be insensitive to measurement position and read distance due to a novel self-referencing technique eliminating the need to measure absolute responses that are dependent on RF transmitter location and power.

  4. SECHAGE DE PRODUITS GRANULAIRES PAR DESHYDRATATION PAR DETENTES SUCCESSIVES (DDS)

    OpenAIRE

    Abdulla , Galal; Mellouk , Hamid; Belghit , Abdelhamid; Allaf , Karim

    2009-01-01

    International audience; Dans cette étude, nous avons évalué les performances d'un nouveau procédé de séchage dans le cas du liège en granulés. Ce procédé (La déshydratation par détentes successives : DDS) consiste à soumettre le matériau liège dans une chambre hermétique aux variations cycliques de la pression. Chaque cycle est composé d'une compression et d'une décompression. La phase de compression est réalisée en injectant de l'air comprimé à température ambiante provenant d'un compresseur...

  5. Passiv-Sammler

    OpenAIRE

    Fritsche, U.

    1991-01-01

    The invention relates to a passive collector for air pollution for the determination of emission rates for dry and wet deposits on construction materials such as natural stone, whereby the collector has a surrogate surface of the stone under investigation, the surrogate surface being linked to a collecting vessel such that any dry or wet contamination occurring can be collected.

  6. Passive houses in Norway

    Energy Technology Data Exchange (ETDEWEB)

    Halse, Andreas

    2008-12-15

    The paper analyzes the introduction of passive houses in the Norwegian house market. Passive houses are houses with extremely low levels of energy consumption for heating, and have not yet been built in Norway, but have started to enter the market in Germany and some other countries. The construction sector is analyzed as a sectoral innovation system. The different elements of the innovation system are studied. This includes government agencies, producers, consumers, finance and education. The analysis shows that passive and low-energy houses are on the verge of market breakthrough. This can partly be explained by economic calculations, and partly by processes of learning and change in the institutional set-up of the sector. The construction sector is a sector characterized by low innovative intensity and little interaction between different agents. Those working to promote passive houses have to some extent managed to cope with these challenges. This has happened by breaking away from the traditional focus of Norwegian energy efficiency policies on technology and the economically rational agents, by instead focusing on knowledge and institutional change at the level of the producers. (Author)

  7. Hood River Passive House

    Energy Technology Data Exchange (ETDEWEB)

    Hales, David [BA-PIRC, Spokane, WA (United States)

    2014-01-01

    The Hood River Passive Project was developed by Root Design Build of Hood River Oregon using the Passive House Planning Package (PHPP) to meet all of the requirements for certification under the European Passive House standards. The Passive House design approach has been gaining momentum among residential designers for custom homes and BEopt modeling indicates that these designs may actually exceed the goal of the U.S. Department of Energy's (DOE) Building America program to "reduce home energy use by 30%-50% (compared to 2009 energy codes for new homes). This report documents the short term test results of the Shift House and compares the results of PHPP and BEopt modeling of the project. The design includes high R-Value assemblies, extremely tight construction, high performance doors and windows, solar thermal DHW, heat recovery ventilation, moveable external shutters and a high performance ductless mini-split heat pump. Cost analysis indicates that many of the measures implemented in this project did not meet the BA standard for cost neutrality. The ductless mini-split heat pump, lighting and advanced air leakage control were the most cost effective measures. The future challenge will be to value engineer the performance levels indicated here in modeling using production based practices at a significantly lower cost.

  8. Passive THz metamaterials

    DEFF Research Database (Denmark)

    Lavrinenko, Andrei; Malureanu, Radu; Zalkovskij, Maksim

    2012-01-01

    In this work we present our activities in the fabrication and characterization of passive THz metamaterials. We use two fabrication processes to develop metamaterials either as free-standing metallic membranes or patterned metallic multi-layers on the substrates to achieve different functionalities...

  9. La preuve par le nombre

    Directory of Open Access Journals (Sweden)

    Hélène Verdier

    2012-04-01

    Full Text Available S’il en était besoin, la question des usages et de la finalité des résultats de l’inventaire général pourrait être abordée par le nombre : nombre d’œuvres répertoriées, de communes inventoriées, de clichés photographiques réalisés, de dossiers, de consultations des notices dans les bases de données… Les additions aujourd’hui sont éloquentes, mais elles laissent dans l’ombre le rôle de l’inventaire qui, en mettant en œuvre une démarche systématique de connaissance, participe à l’ identificatio...

  10. CFD simulation of hydrogen mixing and mitigation by means of passive auto-catalytic recombiners

    International Nuclear Information System (INIS)

    Kelm, S.; Reinecke, E-A.; Jahn, W.; Allelein, H-J.

    2011-01-01

    Modeling of passive auto-catalytic recombiners (PARs) operation in containment geometries involves a large variety of scales; thus, a CFD calculation resolving all these scales would be much too expensive. Therefore, the mechanistic PAR model REKO-DIREKT, developed at Forschungszentrum Juelich, has been coupled with the commercial CFD code ANSYS CFX in order to simulate PAR operation as well as the induced flow and transport phenomena. Based on a short introduction of REKO-DIREKT, its interface to CFX and the explicit coupling scheme is discussed. The paper is finalized by a first demonstration of simulation capabilities on the basis of the ThAI PAR-4 experiment (Becker Technologies GmbH, Eschborn, Germany). (author)

  11. Intrinsically Passive Handling and Grasping

    NARCIS (Netherlands)

    Stramigioli, Stefano; Scherpen, Jacquelien M.A.; Khodabandehloo, Koorosh

    2000-01-01

    The paper presents a control philosophy called Intrinsically Passive Control, which has the feature to properly behave during interaction with any passive objects. The controlled robot will never become unstable due to the physical structure of the controller.

  12. Par Pond vegetation status Summer 1995 -- Summary

    International Nuclear Information System (INIS)

    Mackey, H.E. Jr.; Riley, R.S.

    1996-01-01

    The water level of Par Pond was lowered approximately 20 feet in mid-1991 in order to protect downstream residents from possible dam failure suggested by subsidence on the downstream slope of the dam and to repair the dam. This lowering exposed both emergent and nonemergent macrophyte beds to drying conditions resulting in extensive losses. A survey of the newly emergent, shoreline aquatic plant communities of Par Pond began in June 1995, three months after the refilling of Par Pond to approximately 200 feet above mean sea level. These surveys continued in July, September, and late October, 1995. Communities similar to the pre-drawdown, Par Pond aquatic plant communities are becoming re-established. Emergent beds of maidencane, lotus, waterlily, and watershield are extensive and well developed. Cattail occurrence continued to increase during the summer, but large beds common to Par Pond prior to the drawdown have not formed. Estimates from SPOT HRV, remote sensing satellite data indicated that as much as 120 hectares of emergent wetlands vegetation may have been present along the Par Pond shoreline by early October, 1995. To track the continued development of macrophytes in Par Pond, future surveys throughout 1996 and 1997, along with the continued evaluation of satellite data to map the areal extent of the macrophyte beds of Par Pond, are planned

  13. Passive solar heating

    Energy Technology Data Exchange (ETDEWEB)

    Wiberg, K

    1981-11-10

    The present work treats the possibilities for heating according to the passive solar heating method. Problems of 'spatial organization in an energy-saving society' are distinguished from among other social problems. The final delimination of the actual problems under investigation consists of the use of passive solar heating and especially the 'consequences of such solar heating exploitation upon the form and structures' of planning and construction. In the concluding chapter an applied example shows how this method can be used in designing an urban area and what are its limitations. The results indicate the possibilities and difficulties in attempting to transfer this ideal and general method into models and directives for form and structure from which examples of the actual possibilities in practical planning can be given.

  14. Qademah Fault Passive Data

    KAUST Repository

    Hanafy, Sherif M.

    2014-01-01

    OBJECTIVE: In this field trip we collect passive data to 1. Convert passive to surface waves 2. Locate Qademah fault using surface wave migration INTRODUCTION: In this field trip we collected passive data for several days. This data will be used to find the surface waves using interferometry and then compared to active-source seismic data collected at the same location. A total of 288 receivers are used. A 3D layout with 5 m inline intervals and 10 m cross line intervals is used, where we used 12 lines with 24 receivers at each line. You will need to download the file (rec_times.mat), it contains important information about 1. Field record no 2. Record day 3. Record month 4. Record hour 5. Record minute 6. Record second 7. Record length P.S. 1. All files are converted from original format (SEG-2) to matlab format P.S. 2. Overlaps between records (10 to 1.5 sec.) are already removed from these files

  15. Concept research on general passive system

    International Nuclear Information System (INIS)

    Han Xu; Yang Yanhua; Zheng Mingguang

    2009-01-01

    This paper summarized the current passive techniques used in nuclear power plants. Through classification and analysis, the functional characteristics and inherent identification of passive systems were elucidated. By improving and extending the concept of passive system, the general passive concept was proposed, and space and time relativity was discussed and assumption of general passive system were illustrated. The function of idealized general passive system is equivalent with the current passive system, but the design of idealized general passive system is more flexible. (authors)

  16. ¡París!

    Directory of Open Access Journals (Sweden)

    Beatriz Caballero

    2003-01-01

    Full Text Available El día no le alcanzaba para caminarlo. Conocía cada puente, cada calle,plaza, museo, rincón, iglesia, café, y la mesa con el mejor ángulo para mirar siempre una iglesia, ojalá Saint-Germain-des-Pres, o Notre-Dame. Siempre contaba la impresión que le había causado a Bolívar ver allí cuando el papa coronó a Napoleón. Él se iba para la oficina todos los días, Luis a un taller a pintar, Antonio a estudiar ciencias políticas, yo al colegio y mamá hacía las cosas prácticas. Aprendíamos francés todos al tiempo y por la noche nos contábamos lo nuevo que cada uno había aprendido. Mamá después, cuando ya se quería volver, decía que París nos había maleado a todos. Estaba en pleno furor el cine francés de la "nueva ola", pero ella sólo me llevaba a ver películas de vaqueros pues no se fiaba de la clasificación de los periódicos.

  17. CFD modelling of hydrogen stratification in enclosures: Model validation and application to PAR performance

    Energy Technology Data Exchange (ETDEWEB)

    Hoyes, J.R., E-mail: james.hoyes@hsl.gsi.gov.uk; Ivings, M.J.

    2016-12-15

    Highlights: • The ability of CFD to predict hydrogen stratification phenomena is investigated. • Contrary to expectation, simulations on tetrahedral meshes under-predict mixing. • Simulations on structured meshes give good agreement with experimental data. • CFD model used to investigate the effects of stratification on PAR performance. • Results show stratification can have a significant effect on PAR performance. - Abstract: Computational Fluid Dynamics (CFD) models are maturing into useful tools for supporting safety analyses. This paper investigates the capabilities of CFD models for predicting hydrogen stratification in a containment vessel using data from the NEA/OECD SETH2 MISTRA experiments. Further simulations are then carried out to illustrate the qualitative effects of hydrogen stratification on the performance of Passive Autocatalytic Recombiner (PAR) units. The MISTRA experiments have well-defined initial and boundary conditions which makes them well suited for use in a validation study. Results are presented for the sensitivity to mesh resolution and mesh type. Whilst the predictions are shown to be largely insensitive to the mesh resolution they are surprisingly sensitive to the mesh type. In particular, tetrahedral meshes are found to induce small unphysical convection currents that result in molecular diffusion and turbulent mixing being under-predicted. This behaviour is not unique to the CFD model used here (ANSYS CFX) and furthermore, it may affect simulations run on other non-aligned meshes (meshes that are not aligned perpendicular to gravity), including non-aligned structured meshes. Following existing best practice guidelines can help to identify potential unphysical predictions, but as an additional precaution consideration should be given to using gravity-aligned meshes for modelling stratified flows. CFD simulations of hydrogen recombination in the Becker Technologies THAI facility are presented with high and low PAR positions

  18. Hydrogen Recombination Rates of Plate-type Passive Auto-catalytic Recombiner

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jongtae; Hong, Seong-Wan [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Kim, Gun Hong [Kyungwon E-C Co., Seongnam (Korea, Republic of)

    2014-10-15

    The hydrogen mitigation system may include igniters, passive autocatalytic recombiner (PAR), and venting or dilution system. Recently PAR is commonly used as a main component of HMS in a NPP containment because of its passive nature. PARs are categorized by the shape and material of catalytic surface. Catalytic surface coated by platinum is mostly used for the hydrogen recombiners. The shapes of the catalytic surface can be grouped into plate type, honeycomb type and porous media type. Among them, the plate-type PAR is well tested by many experiments. PAR performance analysis can be approached by a multi-scale method which is composed of micro, meso and macro scales. The criterion of the scaling is the ratio of thickness of boundary layer developed on a catalytic surface to representative length of a computational domain. Mass diffusion in the boundary layer must be resolved in the micro scale analysis. In a lumped parameter (LP) analysis using a system code such as MAAP or MELCOR, the chamber of the PAR is much smaller than a computational node. The hydrogen depletion by a PAR is modeled as a source of mass and energy conservation equations. Te catalytic surface reaction of hydrogen must be modeled by a volume-averaged correlation. In this study, a micro scale analysis method is developed using libraries in OpenFOAM to evaluate a hydrogen depletion rate depending on parameters such as size and number of plates and plate arrangement. The analysis code is validated by simulating REKO-3 experiment. And hydrogen depletion analysis is conducted by changing the plate arrangement as a trial of the performance enhancement of a PAR. In this study, a numerical code for an analysis of a PAR performance in a micro scale has been developed by using OpenFOAM libraries. The physical and numerical models were validated by simulating the REKO-3 experiment. As a try to enhance the performance of the plate-type PAR, it was proposed to apply a staggered two-layer arrangement of the

  19. Hydrogen Recombination Rates of Plate-type Passive Auto-catalytic Recombiner

    International Nuclear Information System (INIS)

    Kim, Jongtae; Hong, Seong-Wan; Kim, Gun Hong

    2014-01-01

    The hydrogen mitigation system may include igniters, passive autocatalytic recombiner (PAR), and venting or dilution system. Recently PAR is commonly used as a main component of HMS in a NPP containment because of its passive nature. PARs are categorized by the shape and material of catalytic surface. Catalytic surface coated by platinum is mostly used for the hydrogen recombiners. The shapes of the catalytic surface can be grouped into plate type, honeycomb type and porous media type. Among them, the plate-type PAR is well tested by many experiments. PAR performance analysis can be approached by a multi-scale method which is composed of micro, meso and macro scales. The criterion of the scaling is the ratio of thickness of boundary layer developed on a catalytic surface to representative length of a computational domain. Mass diffusion in the boundary layer must be resolved in the micro scale analysis. In a lumped parameter (LP) analysis using a system code such as MAAP or MELCOR, the chamber of the PAR is much smaller than a computational node. The hydrogen depletion by a PAR is modeled as a source of mass and energy conservation equations. Te catalytic surface reaction of hydrogen must be modeled by a volume-averaged correlation. In this study, a micro scale analysis method is developed using libraries in OpenFOAM to evaluate a hydrogen depletion rate depending on parameters such as size and number of plates and plate arrangement. The analysis code is validated by simulating REKO-3 experiment. And hydrogen depletion analysis is conducted by changing the plate arrangement as a trial of the performance enhancement of a PAR. In this study, a numerical code for an analysis of a PAR performance in a micro scale has been developed by using OpenFOAM libraries. The physical and numerical models were validated by simulating the REKO-3 experiment. As a try to enhance the performance of the plate-type PAR, it was proposed to apply a staggered two-layer arrangement of the

  20. Passive Power Filters

    CERN Document Server

    Künzi, R.

    2015-06-15

    Power converters require passive low-pass filters which are capable of reducing voltage ripples effectively. In contrast to signal filters, the components of power filters must carry large currents or withstand large voltages, respectively. In this paper, three different suitable filter struc tures for d.c./d.c. power converters with inductive load are introduced. The formulas needed to calculate the filter components are derived step by step and practical examples are given. The behaviour of the three discussed filters is compared by means of the examples. P ractical aspects for the realization of power filters are also discussed.

  1. Thermohydraulic model of GOTHIC 8.0 for the analysis of PAR in NPP Cofrentes; Modelo termohidraulico de GOTHIC 8.0 para el analisis de PAR en C. N. Cofrentes

    Energy Technology Data Exchange (ETDEWEB)

    Jimenez, G.; Lopez-Alonso, E.; Molina, M. c.; Garcia, J.; Serrano, C.; Queral, C.; Gallego, E.

    2013-07-01

    Analysis of the installation of Passive autocatalytic recombiners in CN Cofrentes being developed by Iberdrola Engineering and Construction the support of the UPM. This analysis supports the location and size of the PAR to be installed in the containment drywell and to minimize the risks arising from the release of hydrogen generated during a severe accident and distribution of hydrogen in the containment buildings annexes.

  2. C9.A/14 steelwork joints de poutres par plaque frontale : assemblages par gousset

    CERN Document Server

    2015-01-01

    Les Tables de résistances ultimes des assemblages boulonnés par plaque frontale et par gousset, complétées par une description des modèles de calcul et des exemples d’application, ont pour but de faciliter la tâche de l'ingénieur et du constructeur. Cette première partie C9.A/14 contient les chapitres suivants: - Joints de poutres par plaque frontale en acier S235 et S355 - Assemblages par gousset en acier S235 et S355 Les Tables contiennent des données relatives à la géométrie ainsi que les valeurs de calcul correspondantes des résistances ultimes des assemblages ; elles remplacent le chapitre « Assemblages par plaques frontales et boulons HR » des anciennes Tables C9.1 de 1983 / 2002. Le calcul de ces assemblages par plaque frontale est basé sur les hypothèses du modèle de la méthode des composants décrite dans la norme SN EN 1993-1-8. Les vérifications sont effectuées selon la norme SIA 263:2013. Les assemblages par gousset remplacent les assemblages par double cornière, (telle...

  3. Expansion of passive safety function

    International Nuclear Information System (INIS)

    Inai, Nobuhiko; Nei, Hiromichi; Kumada, Toshiaki.

    1995-01-01

    Expansion of the use of passive safety functions is proposed. Two notions are presented. One is that, in the design of passive safety nuclear reactors where aversion of active components is stressed, some active components are purposely introduced, by which a system is built in such a way that it behaves in an apparently passive manner. The second notion is that, instead of using a passive safety function alone, a passive safety function is combined with some active components, relating the passivity in the safety function with enhanced controllability in normal operation. The nondormant system which the authors propose is one example of the first notion. This is a system in which a standby safety system is a portion of the normal operation system. An interpretation of the nondormant system via synergetics is made. As an example of the second notion, a PIUS density lock aided with active components is proposed and is discussed

  4. Passive cooling containment study

    International Nuclear Information System (INIS)

    Shin, J.J.; Iotti, R.C.; Wright, R.F.

    1993-01-01

    Pressure and temperature transients of nuclear reactor containment following postulated loss of coolant accident with a coincident station blackout due to total loss of all alternating current power are studied analytically and experimentally for the full scale NPR (New Production Reactor). All the reactor and containment cooling under this condition would rely on the passive cooling system which removes reactor decay heat and provides emergency core and containment cooling. Containment passive cooling for this study takes place in the annulus between containment steel shell and concrete shield building by natural convection air flow and thermal radiation. Various heat transfer coefficients inside annular air space were investigated by running the modified CONTEMPT code CONTEMPT-NPR. In order to verify proper heat transfer coefficient, temperature, heat flux, and velocity profiles were measured inside annular air space of the test facility which is a 24 foot (7.3m) high, steam heated inner cylinder of three foot (.91m) diameter and five and half foot (1.7m) diameter outer cylinder. Comparison of CONTEMPT-NPR and WGOTHIC was done for reduced scale NPR

  5. Fly ash carbon passivation

    Science.gov (United States)

    La Count, Robert B; Baltrus, John P; Kern, Douglas G

    2013-05-14

    A thermal method to passivate the carbon and/or other components in fly ash significantly decreases adsorption. The passivated carbon remains in the fly ash. Heating the fly ash to about 500 and 800 degrees C. under inert gas conditions sharply decreases the amount of surfactant adsorbed by the fly ash recovered after thermal treatment despite the fact that the carbon content remains in the fly ash. Using oxygen and inert gas mixtures, the present invention shows that a thermal treatment to about 500 degrees C. also sharply decreases the surfactant adsorption of the recovered fly ash even though most of the carbon remains intact. Also, thermal treatment to about 800 degrees C. under these same oxidative conditions shows a sharp decrease in surfactant adsorption of the recovered fly ash due to the fact that the carbon has been removed. This experiment simulates the various "carbon burnout" methods and is not a claim in this method. The present invention provides a thermal method of deactivating high carbon fly ash toward adsorption of AEAs while retaining the fly ash carbon. The fly ash can be used, for example, as a partial Portland cement replacement in air-entrained concrete, in conductive and other concretes, and for other applications.

  6. Surface Passivation in Empirical Tight Binding

    OpenAIRE

    He, Yu; Tan, Yaohua; Jiang, Zhengping; Povolotskyi, Michael; Klimeck, Gerhard; Kubis, Tillmann

    2015-01-01

    Empirical Tight Binding (TB) methods are widely used in atomistic device simulations. Existing TB methods to passivate dangling bonds fall into two categories: 1) Method that explicitly includes passivation atoms is limited to passivation with atoms and small molecules only. 2) Method that implicitly incorporates passivation does not distinguish passivation atom types. This work introduces an implicit passivation method that is applicable to any passivation scenario with appropriate parameter...

  7. Passive-solar construction handbook

    Energy Technology Data Exchange (ETDEWEB)

    Levy, E.; Evans, D.; Gardstein, C.

    1981-02-01

    Many of the basic elements of passive solar design are reviewed. Passive solar construction is covered according to system type, each system type discussion including a general discussion of the important design and construction issues which apply to the particular system and case studies illustrating designed and built examples of the system type. The three basic types of passive solar systems discussed are direct gain, thermal storage wall, and attached sunspace. Thermal performance and construction information is presented for typical materials used in passive solar collector components, storage components, and control components. Appended are an overview of analysis methods and a technique for estimating performance. (LEW)

  8. Protease-activated receptor (PAR)-2 is required for PAR-1 signalling in pulmonary fibrosis

    NARCIS (Netherlands)

    Lin, Cong; von der Thüsen, Jan; Daalhuisen, Joost; ten Brink, Marieke; Crestani, Bruno; van der Poll, Tom; Borensztajn, Keren; Spek, C. Arnold

    2015-01-01

    Idiopathic pulmonary fibrosis is the most devastating diffuse fibrosing lung disease of unknown aetiology. Compelling evidence suggests that both protease-activated receptor (PAR)-1 and PAR-2 participate in the development of pulmonary fibrosis. Previous studies have shown that bleomycin-induced

  9. Passive magnetic bearing system

    Science.gov (United States)

    Post, Richard F.

    2014-09-02

    An axial stabilizer for the rotor of a magnetic bearing provides external control of stiffness through switching in external inductances. External control also allows the stabilizer to become a part of a passive/active magnetic bearing system that requires no external source of power and no position sensor. Stabilizers for displacements transverse to the axis of rotation are provided that require only a single cylindrical Halbach array in its operation, and thus are especially suited for use in high rotation speed applications, such as flywheel energy storage systems. The elimination of the need of an inner cylindrical array solves the difficult mechanical problem of supplying support against centrifugal forces for the magnets of that array. Compensation is provided for the temperature variation of the strength of the magnetic fields of the permanent magnets in the levitating magnet arrays.

  10. European vehicle passive safety network

    NARCIS (Netherlands)

    Wismans, J.S.H.M.; Janssen, E.G.

    1999-01-01

    The general objective of the European Vehicle Passive Safety Network is to contribute to the reduction of the number of road traffic victims in Europe by passive safety measures. The aim of the road safety policy of the European Commission is to reduce the annual total of fatalities to 18000 in

  11. Passive films at the nanoscale

    International Nuclear Information System (INIS)

    Maurice, Vincent; Marcus, Philippe

    2012-01-01

    Highlights: ► Nanoscale data on growth, structure and local properties of passive films reviewed. ► Preferential role of defects of passive films on the corrosion resistance emphasized. ► Effect of grain boundaries on local electronic properties shown by new data. ► Use of atomistic modeling to test mechanistic hypotheses illustrated. - Abstract: The nanometer scale chemical and structural aspects of ultrathin oxide passive films providing self-protection against corrosion to metals and alloys in aqueous environments are reviewed. Data on the nucleation and growth of 2D anodic oxide films, details on the atomic structure and nanostructure of 3D passive films, the preferential role of surface step edges in dissolution in the passive state and the preferential role of grain boundaries of the passive films in passivity breakdown are presented. Future perspectives are discussed, and exemplified by new data obtained on the relationship between the nanostructure of oxide passive films and their local electronic properties. Atomistic corrosion modeling by ab initio density functional theory (DFT) is illustrated by the example of interactions of chloride ions with hydroxylated oxide surfaces, including the role of surface step edges. Data obtained on well-defined substrate surfaces with surface analytical techniques are emphasized.

  12. Udviklingen i bilers passive sikkerhed

    DEFF Research Database (Denmark)

    Hels, Tove; Lyckegaard, Allan; Prato, Carlo Giacomo

    man mellem aktiv og passiv sikkerhed, det vil sige faktorer, der nedsætter • risikoen for, at der sker et uheld (aktiv sikkerhed), henholdsvis • graden af alvorlighed, givet at uheldet er sket (passiv sikkerhed). Rapporten begrænser sig til at undersøge, om der kan påvises en generel sammenhæng mellem...

  13. The Passive in Singapore English.

    Science.gov (United States)

    Bao, Zhiming; Wee, Lionel

    1999-01-01

    Presents an analysis of the two passive (or passive-like) constructions in Singapore English which exhibit substrate influence from Malay and Chinese. The paper shows that while substrate languages contribute to the grammar of Singapore English, the continued prestige of standard English exerts normative pressure and mitigates the effect of…

  14. Development and testing of passive autocatalytic recombiners cooled by heat pipes

    International Nuclear Information System (INIS)

    Granzow, Christoph

    2012-01-01

    A severe accident in a nuclear power plant (NPP) can lead to core damage in conjunction with the release of large amounts of hydrogen. As hydrogen mitigation measure, passive autocatalytic recombiners (PARs) are used in today's pressurized water reactors. PARs recombine hydrogen and oxygen contained in the air to steam. The heat from this exothermic reaction causes the catalyst and its surroundings to heat up. If parts of the PAR heat up above the ignition temperature of the gas mixture, a spontaneous deflagration or detonation can occur. The aim of this work is the prevention of such high temperatures by means of passive cooling of the catalyst with heat pipes. Heat pipes are completely passive heat exchanger with a very high effective thermal conductivity. For a deeper understanding of the reaction kinetics at lower temperatures, single catalytic coated heat pipes are studied in a flow reactor. The development of a modular small-scale PAR model is then based on a test series with cooled catalyst sheets. Finally, the PAR model is tested inside a pressure vessel under boundary conditions similar to a real NPP. The experiments show, that the temperatures of the cooled catalytic sheets stay significantly below the temperature of the uncooled sheets and below the ignition temperature of the gas mixture under any set boundary conditions, although no significant reduction of the conversion efficiency can be observed. As a last point, a mathematical model of the reaction kinetics of the recombination process as well as a model of the fluid dynamic and thermohydraulic processes in a heat pipe are developed with the data obtained from the experiments.

  15. State of the art on hydrogen passive auto-catalytic recombiner (european union Parsoar project)

    International Nuclear Information System (INIS)

    Arnould, F.; Bachellerie, E.; Auglaire, M.; Boeck, B. de; Braillard, O.; Eckardt, B.; Ferroni, F.; Moffett, R.; Van Goethem, G.

    2001-01-01

    This paper presents an overview of the European Union PARSOAR project, which consists in carrying out a state of the art on hydrogen passive auto-catalytic recombiner (PAR) and a handbook guide for implementing these devices in nuclear power plants. This work is performed in the area ''Operational Safety of Existing Installations'' of the key action ''Nuclear Fission'' of the fifth Euratom Framework Programme (1998-2002). (author)

  16. State of the art on hydrogen passive auto-catalytic recombiner (european union Parsoar project)

    Energy Technology Data Exchange (ETDEWEB)

    Arnould, F.; Bachellerie, E. [Technicatome, 13 - Aix en Provence (France); Auglaire, M. [Tractebel Energy Engineering, Brussels (Belgium); Boeck, B. de [Association Vincotte Nuclear, Brussels (Belgium); Braillard, O. [CEA Cadarache, 13 - Saint Paul lez Durance (France); Eckardt, B. [Siemens AG, Offenbach am Main (Germany); Ferroni, F. [Electrowatt Engineering Limited, Zurich (Switzerland); Moffett, R. [Atomic Energy Canada Limited, Pinawa (Canada); Van Goethem, G. [European Commission, Brussels (Belgium)

    2001-07-01

    This paper presents an overview of the European Union PARSOAR project, which consists in carrying out a state of the art on hydrogen passive auto-catalytic recombiner (PAR) and a handbook guide for implementing these devices in nuclear power plants. This work is performed in the area ''Operational Safety of Existing Installations'' of the key action ''Nuclear Fission'' of the fifth Euratom Framework Programme (1998-2002). (author)

  17. Antireflection/Passivation Step For Silicon Cell

    Science.gov (United States)

    Crotty, Gerald T.; Kachare, Akaram H.; Daud, Taher

    1988-01-01

    New process excludes usual silicon oxide passivation. Changes in principal electrical parameters during two kinds of processing suggest antireflection treatment almost as effective as oxide treatment in passivating cells. Does so without disadvantages of SiOx passivation.

  18. Analysis of passive autocatalytic recombiners installation in Cofrentes NPP

    International Nuclear Information System (INIS)

    Del Carmen Molina, Cesar Serrano; Jimenez, Gonzalo

    2014-01-01

    The analysis of Passive Autocatalytic Recombiners (PAR) installation in Cofrentes NPP is a regulatory requirement from the stress tests carried out due to the Fukushima accident. The analysis has been developed by IIC with the support of UPM-ETSII, and defines the PARs configuration to be installed into the containment/drywell to minimize the risks derived from hydrogen generation during a severe accident. The analysis has been developed in three stages: - Generation and release of hydrogen in containment/drywell: The mass and energy sources releases are analysed with MAAP4.0.7 code and covers all phases of the severe accident in-vessel and ex-vessel. Probabilistic and deterministic criteria were used to select the accident sequences. Model sensitivities analyses were included maximizing the global hydrogen releases as well as the peak values. - Distribution of hydrogen in containment/drywell: Hydrogen and other gases distribution is developed with GOTHIC 8.0 code using a 3D detailed model. Long term simulation necessities were taken into account during model adjustment. Model verification was carried out by comparing the results with several experimental data and simulations with other thermohydraulic codes, both covering the range of simulation. The model considers mass and energy discharges in the suppression pool as well as and in the containment atmosphere and takes into account heat transfer and condensation process. In addition, the influence of containment systems activation has been evaluated. - PAR sizing and locating: The location and size analysis of PAR considers the hydrogen depletion rates and operating conditions of different equipment. Furthermore, a post processing treatment has been developed to deeply analyse all parameters involved in the combustion phenomena and thus identify the risks zones. The study takes into account different distribution options regarding cost and operational criteria. Walk-downs were carried out for a realistic

  19. ParA and ParB coordinate chromosome segregation with cell elongation and division during Streptomyces sporulation

    Science.gov (United States)

    Donczew, Magdalena; Mackiewicz, Paweł; Wróbel, Agnieszka; Flärdh, Klas; Zakrzewska-Czerwińska, Jolanta

    2016-01-01

    In unicellular bacteria, the ParA and ParB proteins segregate chromosomes and coordinate this process with cell division and chromosome replication. During sporulation of mycelial Streptomyces, ParA and ParB uniformly distribute multiple chromosomes along the filamentous sporogenic hyphal compartment, which then differentiates into a chain of unigenomic spores. However, chromosome segregation must be coordinated with cell elongation and multiple divisions. Here, we addressed the question of whether ParA and ParB are involved in the synchronization of cell-cycle processes during sporulation in Streptomyces. To answer this question, we used time-lapse microscopy, which allows the monitoring of growth and division of single sporogenic hyphae. We showed that sporogenic hyphae stop extending at the time of ParA accumulation and Z-ring formation. We demonstrated that both ParA and ParB affect the rate of hyphal extension. Additionally, we showed that ParA promotes the formation of massive nucleoprotein complexes by ParB. We also showed that FtsZ ring assembly is affected by the ParB protein and/or unsegregated DNA. Our results indicate the existence of a checkpoint between the extension and septation of sporogenic hyphae that involves the ParA and ParB proteins. PMID:27248800

  20. Contamination potentielle des aliments par des ...

    African Journals Online (AJOL)

    SARA Computers

    la notion de la pollution et de l'exposition aux PCBs, lorsque 77% n'ont pas conscience de cette situation de risque ... 2018). Quoique la contamination par les. PCBs soit de faible niveau, elle est ...... Université Paris-Est, Paris, France ; 183.

  1. French concepts of ''passive safety''

    International Nuclear Information System (INIS)

    Dennielou, Y.; Serret, M.

    1990-01-01

    N 4 model, the French 1400 MW PWR of the 90's, exhibits many advanced features. As far as safety is concerned, the fully computerized control room design takes advantage of the operating experience feedback and largely improves the man machine interface. New post-accident procedures have been developed (the so-called ''physical states oriented procedures''). A complete consistent set of ''Fundamental Safety Rules'' have been issued. This however doesn't imply any significant modification of standard PWR with regard to the passive aspects of safety systems or functions. Nevertheless, traditional PWR safety systems largely use passive aspects: natural circulation, reactivity coefficients, gravity driven control rods, injection accumulators, so on. Moreover, probability calculations allow for comparison between the respective contributions of passive and of active failures. In the near future, eventual options of future French PWRs to be commissioned after 2000 will be evaluated; simplification, passive and forgiving aspects of safety systems will be thoroughly considered. (author)

  2. Effectiveness of passive alcohol sensors

    Science.gov (United States)

    1996-03-01

    Author's abstract: The purpose of this study was to evaluate the effectiveness of passive alcohol sensors for youth alcohol enforcement conducted as part of normal or typical police operations. Three municipal police departments of 100 or more sworn ...

  3. Passive heat removal in CANDU

    International Nuclear Information System (INIS)

    Hart, R.S.

    1997-01-01

    CANDU has a tradition of incorporating passive systems and passive components whenever they are shown to offer performance that is equal to or better than that of active systems, and to be economic. Examples include the two independent shutdown systems that employ gravity and stored energy respectively, the dousing subsystem of the CANDU 6 containment system, and the ability of the moderator to cool the fuel in the event that all coolant is lost from the fuel channels. CANDU 9 continues this tradition, incorporating a reserve water system (RWS) that increases the inventory of water in the reactor building and profiles a passive source of makeup water and/or heat sinks to various key process systems. The key component of the CANDU 9 reserve water system is a large (2500 cubic metres) water tank located at a high elevation in the reactor building. The reserve water system, while incorporating the recovery system functions, and the non-dousing functions of the dousing tank in CANDU 6, embraces other key systems to significantly extend the passive makeup/heat sink capability. The capabilities of the reserve water system include makeup to the steam generators secondary side if all other sources of water are lost; makeup to the heat transport system in the event of a leak in excess of the D 2 O makeup system capability; makeup to the moderator in the event of a moderator leak when the moderator heat sink is required; makeup to the emergency core cooling (ECC) system to assure NPSH to the ECC pumps during a loss of coolant accident (LOCA), and provision of a passive heat sink for the shield cooling system. Other passive designs are now being developed by AECL. These will be incorporated in future CANDU plants when their performance has been fully proven. This paper reviews the passive heat removal systems and features of current CANDU plants and the CANDU 9, and briefly reviews some of the passive heat removal concepts now being developed. (author)

  4. Key issues for passive safety

    International Nuclear Information System (INIS)

    Hayns, M.R.

    1996-01-01

    The paper represents a summary of the introductory presentation made at this Advisory Group Meeting on the Technical Feasibility and Reliability of Passive Safety Systems. It was intended as an overview of our views on what are the key issues and what are the technical problems which might dominate any future developments of passive safety systems. It is, therefore, not a ''review paper'' as such and only record the highlights. (author)

  5. Key issues for passive safety

    Energy Technology Data Exchange (ETDEWEB)

    Hayns, M R [AEA Technology, Harwell, Didcot (United Kingdom). European Institutions; Hicken, E F [Forschungszentrum Juelich GmbH (Germany)

    1996-12-01

    The paper represents a summary of the introductory presentation made at this Advisory Group Meeting on the Technical Feasibility and Reliability of Passive Safety Systems. It was intended as an overview of our views on what are the key issues and what are the technical problems which might dominate any future developments of passive safety systems. It is, therefore, not a ``review paper`` as such and only record the highlights. (author).

  6. Passive vapor extraction feasibility study

    International Nuclear Information System (INIS)

    Rohay, V.J.

    1994-01-01

    Demonstration of a passive vapor extraction remediation system is planned for sites in the 200 West Area used in the past for the disposal of waste liquids containing carbon tetrachloride. The passive vapor extraction units will consist of a 4-in.-diameter pipe, a check valve, a canister filled with granular activated carbon, and a wind turbine. The check valve will prevent inflow of air that otherwise would dilute the soil gas and make its subsequent extraction less efficient. The granular activated carbon is used to adsorb the carbon tetrachloride from the air. The wind turbine enhances extraction rates on windy days. Passive vapor extraction units will be designed and operated to meet all applicable or relevant and appropriate requirements. Based on a cost analysis, passive vapor extraction was found to be a cost-effective method for remediation of soils containing lower concentrations of volatile contaminants. Passive vapor extraction used on wells that average 10-stdft 3 /min air flow rates was found to be more cost effective than active vapor extraction for concentrations below 500 parts per million by volume (ppm) of carbon tetrachloride. For wells that average 5-stdft 3 /min air flow rates, passive vapor extraction is more cost effective below 100 ppm

  7. SAFARI 2000 PAR Measurements, Kalahari Transect, Botswana, Wet Season 2000

    Data.gov (United States)

    National Aeronautics and Space Administration — Ceptometer data from a Decagon AccuPAR (Model PAR-80) were collected at four sites in Botswana during the SAFARI 2000 Kalahari Transect Wet Season Campaign (March,...

  8. CFD Recombiner Modelling and Validation on the H2-Par and Kali-H2 Experiments

    International Nuclear Information System (INIS)

    Mimouni, S.; Mechitoua, N.; Ouraou, M.

    2011-01-01

    A large amount of Hydrogen gas is expected to be released within the dry containment of a pressurized water reactor (PWR), shortly after the hypothetical beginning of a severe accident leading to the melting of the core. According to local gas concentrations, the gaseous mixture of hydrogen, air and steam can reach the flammability limit, threatening the containment integrity. In order to prevent mechanical loads resulting from a possible conflagration of the gas mixture, French and German reactor containments are equipped with passive autocatalytic recombiners (PARs) which preventively oxidize hydrogen for concentrations lower than that of the flammability limit. The objective of the paper is to present numerical assessments of the recombiner models implemented in CFD solvers NEPTUNE C FD and Code S aturne. Under the EDF/EPRI agreement, CEA has been committed to perform 42 tests of PARs. The experimental program named KALI-H 2 , consists checking the performance and behaviour of PAR. Unrealistic values for the gas temperature are calculated if the conjugate heat transfer and the wall steam condensation are not taken into account. The combined effects of these models give a good agreement between computational results and experimental data

  9. Plasma suPAR is lowered by smoking cessation

    DEFF Research Database (Denmark)

    Eugen-Olsen, Jesper; Ladelund, Steen; Sørensen, Lars Tue

    2016-01-01

    BACKGROUND: Soluble urokinase plasminogen activator receptor (suPAR) is a stable inflammatory biomarker. In patients, suPAR is a marker of disease presence, severity and prognosis. In the general population, suPAR is predictive of disease development, such as diabetes and cardiovascular disease a...

  10. Copenhagen uPAR prostate cancer (CuPCa) database

    DEFF Research Database (Denmark)

    Lippert, Solvej; Berg, Kasper D; Høyer-Hansen, Gunilla

    2016-01-01

    AIM: Urokinase plasminogen activator receptor (uPAR) plays a central role during cancer invasion by facilitating pericellular proteolysis. We initiated the prospective 'Copenhagen uPAR Prostate Cancer' study to investigate the significance of uPAR levels in prostate cancer (PCa) patients. METHODS...

  11. The inflammatory marker suPAR after cardiac arrest

    DEFF Research Database (Denmark)

    Rundgren, Malin; Lyngbaek, Stig; Fisker, Helle

    2015-01-01

    . This pilot study aimed at investigating suPAR levels in relation to outcome after CA and mild induced hypothermia. METHODS: suPAR levels were measured at 6, 36, and 72 hours in patients treated with hypothermia after CA. suPAR levels were analyzed in relation to survival after 6 months. Receiver operating...

  12. Phosphorylation of Mycobacterium tuberculosis ParB participates in regulating the ParABS chromosome segregation system.

    Science.gov (United States)

    Baronian, Grégory; Ginda, Katarzyna; Berry, Laurence; Cohen-Gonsaud, Martin; Zakrzewska-Czerwińska, Jolanta; Jakimowicz, Dagmara; Molle, Virginie

    2015-01-01

    Here, we present for the first time that Mycobacterium tuberculosis ParB is phosphorylated by several mycobacterial Ser/Thr protein kinases in vitro. ParB and ParA are the key components of bacterial chromosome segregation apparatus. ParB is a cytosolic conserved protein that binds specifically to centromere-like DNA parS sequences and interacts with ParA, a weak ATPase required for its proper localization. Mass spectrometry identified the presence of ten phosphate groups, thus indicating that ParB is phosphorylated on eight threonines, Thr32, Thr41, Thr53, Thr110, Thr195, and Thr254, Thr300, Thr303 as well as on two serines, Ser5 and Ser239. The phosphorylation sites were further substituted either by alanine to prevent phosphorylation or aspartate to mimic constitutive phosphorylation. Electrophoretic mobility shift assays revealed a drastic inhibition of DNA-binding by ParB phosphomimetic mutant compared to wild type. In addition, bacterial two-hybrid experiments showed a loss of ParA-ParB interaction with the phosphomimetic mutant, indicating that phosphorylation is regulating the recruitment of the partitioning complex. Moreover, fluorescence microscopy experiments performed in the surrogate Mycobacterium smegmatis ΔparB strain revealed that in contrast to wild type Mtb ParB, which formed subpolar foci similar to M. smegmatis ParB, phoshomimetic Mtb ParB was delocalized. Thus, our findings highlight a novel regulatory role of the different isoforms of ParB representing a molecular switch in localization and functioning of partitioning protein in Mycobacterium tuberculosis.

  13. Phosphorylation of Mycobacterium tuberculosis ParB participates in regulating the ParABS chromosome segregation system.

    Directory of Open Access Journals (Sweden)

    Grégory Baronian

    Full Text Available Here, we present for the first time that Mycobacterium tuberculosis ParB is phosphorylated by several mycobacterial Ser/Thr protein kinases in vitro. ParB and ParA are the key components of bacterial chromosome segregation apparatus. ParB is a cytosolic conserved protein that binds specifically to centromere-like DNA parS sequences and interacts with ParA, a weak ATPase required for its proper localization. Mass spectrometry identified the presence of ten phosphate groups, thus indicating that ParB is phosphorylated on eight threonines, Thr32, Thr41, Thr53, Thr110, Thr195, and Thr254, Thr300, Thr303 as well as on two serines, Ser5 and Ser239. The phosphorylation sites were further substituted either by alanine to prevent phosphorylation or aspartate to mimic constitutive phosphorylation. Electrophoretic mobility shift assays revealed a drastic inhibition of DNA-binding by ParB phosphomimetic mutant compared to wild type. In addition, bacterial two-hybrid experiments showed a loss of ParA-ParB interaction with the phosphomimetic mutant, indicating that phosphorylation is regulating the recruitment of the partitioning complex. Moreover, fluorescence microscopy experiments performed in the surrogate Mycobacterium smegmatis ΔparB strain revealed that in contrast to wild type Mtb ParB, which formed subpolar foci similar to M. smegmatis ParB, phoshomimetic Mtb ParB was delocalized. Thus, our findings highlight a novel regulatory role of the different isoforms of ParB representing a molecular switch in localization and functioning of partitioning protein in Mycobacterium tuberculosis.

  14. [Ambroise Paré in French literature].

    Science.gov (United States)

    Dumaitre, P

    1995-01-01

    The 16th century by its passionate side has been the favourite one of authors of historical novels in which among the heroes of "cloak and dagger stories" appears sometime Ambroise Paré. Alexandre Dumas (the father) has shown him at the court of Charles IX in La Reine Margot (1845) where he does not however play a great role. On the contrary, Balzac in Le Martyr calviniste (1842) has given him a capital part close to the dying François II, whom he intended to trepanize but had to give up this idea as a consequence of the opposition of the queen-mother Catherine de Médicis. In the present century, Robert Merle in Paris ma bonne ville (Fortune de France, 3, 1980) shows Paré at the time of the Saint Barthélemy.

  15. Par Pond refill water quality sampling

    International Nuclear Information System (INIS)

    Koch, J.W. II; Martin, F.D.; Westbury, H.M.

    1996-08-01

    This study was designed to document anoxia and its cause in the event that the anoxia caused a fish kill. However, no fish kill was observed during this study, and dissolved oxygen and nutrient concentrations generally remained within the range expected for southeastern reservoirs. Par Pond water quality monitoring will continue during the second summer after refill as the aquatic macrophytes become reestablished and nutrients in the sediments are released to the water column

  16. Materials for passively safe reactors

    International Nuclear Information System (INIS)

    Simnad, T.

    1993-01-01

    Future nuclear power capacity will be based on reactor designs that include passive safety features if recent progress in advanced nuclear power developments is realized. There is a high potential for nuclear systems that are smaller and easier to operate than the current generation of reactors, especially when passive or intrinsic characteristics are applied to provide inherent stability of the chain reaction and to minimize the burden on equipment and operating personnel. Taylor, has listed the following common generic technical features as the most important goals for the principal reactor development systems: passive stability, simplification, ruggedness, case of operation, and modularity. Economic competitiveness also depends on standardization and assurance of licensing. The performance of passively safe reactors will be greatly influenced by the successful development of advanced fuels and materials that will provide lower fuel-cycle costs. A dozen new designs of advanced power reactors have been described recently, covering a wide spectrum of reactor types, including pressurized water reactors, boiling water reactors, heavy-water reactors, modular high-temperature gas-cooled reactors (MHTGRs), and fast breeder reactors. These new designs address the need for passive safety features as well as the requirement of economic competitiveness

  17. Centromere pairing by a plasmid-encoded type I ParB protein

    DEFF Research Database (Denmark)

    Ringgaard, Simon; Löwe, Jan; Gerdes, Kenn

    2007-01-01

    The par2 locus of Escherichia coli plasmid pB171 encodes two trans-acting proteins, ParA and ParB, and two cis-acting sites, parC1 and parC2, to which ParB binds cooperatively. ParA is related to MinD and oscillates in helical structures and thereby positions ParB/parC-carrying plasmids regularly......, hence identifying the N terminus of ParB as a requirement for ParB-mediated centromere pairing. These observations suggest that centromere pairing is an important intermediate step in plasmid partitioning mediated by the common type I loci....

  18. Passive inhalation of cannabis smoke

    Energy Technology Data Exchange (ETDEWEB)

    Law, B; Mason, P A; Moffat, A C; King, L J; Marks, V

    1984-09-01

    Six volunteers each smoked simultaneously, in a small unventilated room (volume 27 950 liter), a cannabis cigarette containing 17.1 mg delta 9-tetrahydrocannabinol (THC). A further four subjects - passive inhalers - remained in the room during smoking and afterwards for a total of 3 h. Blood and urine samples were taken from all ten subjects and analyzed by radioimmunoassay for THC metabolites. The blood samples from the passive subjects taken up to 3 h after the start of exposure to cannabis smoke showed a complete absence of cannabinoids. In contrast, their urine samples taken up to 6 h after exposure showed significant concentrations of cannabinoid metabolites (less than or equal to 6.8 ng ml-1). These data, taken with the results of other workers, show passive inhalation of cannabis smoke to be possible. These results have important implications for forensic toxicologists who are frequently called upon to interpret cannabinoid levels in body fluids.

  19. Active Versus Passive Academic Networking

    DEFF Research Database (Denmark)

    Goel, Rajeev K.; Grimpe, Christoph

    2013-01-01

    This paper examines determinants of networking by academics. Using information from a unique large survey of German researchers, the key contribution focuses on the active versus passive networking distinction. Is active networking by researchers a substitute or a complement to passive networking......? Other contributions include examining the role of geographic factors in networking and whether research bottlenecks affect a researcher's propensity to network. Are the determinants of European conference participation by German researchers different from conferences in rest of the world? Results show...... that some types of passive academic networking are complementary to active networking, while others are substitute. Further, we find differences in factors promoting participation in European conferences versus conferences in rest of the world. Finally, publishing bottlenecks as a group generally do...

  20. Protocol Monitoring Passive Solar Energy

    International Nuclear Information System (INIS)

    Van den Ham, E.R.; Bosselaar, L.

    1998-01-01

    A method has been developed by means of which the contribution of passive solar energy to the Dutch energy balance can be quantified univocally. The contribution was 57 PJ in 1990 and also 57 PJ in 1995. The efficiency of passive solar energy systems increased from -31.5% to -28.1% in the period 1990-1995, mainly as a result of the use of extra insulating glazing. As a result of the reduction of energy consumption for heating in houses it is expected that the extra contribution of 2 PJ will not be realized in the year 2010. It is suggested that the method to determine the absolute contribution of passive solar energy to the energy demand of dwellings is to be included in the protocol monitoring renewable energy. For the method to be included in the energy statistics of Statistics Netherlands (CBS) it can be considered only to take into account the difference compared to 1990. 11 refs

  1. Passivation of high temperature superconductors

    Science.gov (United States)

    Vasquez, Richard P. (Inventor)

    1991-01-01

    The surface of high temperature superconductors such as YBa2Cu3O(7-x) are passivated by reacting the native Y, Ba and Cu metal ions with an anion such as sulfate or oxalate to form a surface film that is impervious to water and has a solubility in water of no more than 10(exp -3) M. The passivating treatment is preferably conducted by immersing the surface in dilute aqueous acid solution since more soluble species dissolve into the solution. The treatment does not degrade the superconducting properties of the bulk material.

  2. Investigations on passive containment cooling

    International Nuclear Information System (INIS)

    Knebel, J.U.; Cheng, X.; Neitzel, H.J.; Erbacher, F.J.; Hofmann, F.

    1997-01-01

    The composite containment design for advanced LWRs that has been examined under the PASCO project is a promising design concept for purely passive decay heat removal after a severe accident. The passive cooling processes applied are natural convection and radiative heat transfer. Heat transfer through the latter process removes at an emission coefficient of 0.9 about 50% of the total heat removed via the steel containment, and thus is an essential factor. The heat transferring surfaces must have a high emission coefficient. The sump cooling concept examined under the SUCO project achieves a steady, natural convection-driven flow from the heat source to the heat sink. (orig./CB) [de

  3. Passive solar offices: integrated design

    Energy Technology Data Exchange (ETDEWEB)

    Evans, B

    1992-05-06

    Passive solar design in out-of-town offices can remove the need for air-conditioning by making greater use of daylight and natural ventilation. To promote the use of passive solar energy a series of design studies are being run by the Energy Technology Support Unit on behalf of the Department of Energy. The three reported here are designs for out-of-town business buildings. Each is a hypothetical building designed to a realistic brief for an organisation taking the role of real client. (author).

  4. The Danish Reportive Passive as a Non-Canonical Passive

    DEFF Research Database (Denmark)

    Ørsnes, Bjarne

    2013-01-01

    Danish passive utterance and cognitive verbs allow a construction where the subject of an infinitival complement is raised: Peter siges at være bortrejst (‘Peter is said to be out of town’). Contrary to English, these verbs are not ECM-verbs or subject-to-object raising verbs in the active...

  5. First experience with the installation of passive autocatalytic recombiners

    International Nuclear Information System (INIS)

    Snoeck, J.; Solaro, C.; Moeyaert, P.

    1997-01-01

    From the principle decision of installing Passive Autocatalytic Recombiners (PARs) in all Belgian NPPs to the installation on site, several problems needed to be identified and solved; it is the goal of this paper to address these issues and to present the solutions which were adopted. The first section deals with the sizing and the distribution of the catalytic surface inside the containment to be equipped. Rather than to rely on numerous multicompartment calculations, the procedure is based on a single volume approach combined with engineering judgement. The criteria applied in the successive design steps are explained and illustrated for the Doel1 unit. The second section is devoted to additional requirements concerning the resistance to poisoning agents and the maintenance constraints, and to some recommendations for the design of the supports. Because the effectiveness of the PARs entirely relies on the catalyst material, a periodic control of the active parts is of primary importance. Therefore, the Transportable In-Service Inspection Equipment (TIIE) and the test procedures are presented in the third section. Finally, recommendations are made for further work, derived from this first experience. (author)

  6. Development and testing of passive autocatalytic recombiners cooled by heat pipes; Entwicklung und Erprobung mittels Heatpipe gekuehlter katalytischer Rekombinatoren

    Energy Technology Data Exchange (ETDEWEB)

    Granzow, Christoph

    2012-11-26

    A severe accident in a nuclear power plant (NPP) can lead to core damage in conjunction with the release of large amounts of hydrogen. As hydrogen mitigation measure, passive autocatalytic recombiners (PARs) are used in today's pressurized water reactors. PARs recombine hydrogen and oxygen contained in the air to steam. The heat from this exothermic reaction causes the catalyst and its surroundings to heat up. If parts of the PAR heat up above the ignition temperature of the gas mixture, a spontaneous deflagration or detonation can occur. The aim of this work is the prevention of such high temperatures by means of passive cooling of the catalyst with heat pipes. Heat pipes are completely passive heat exchanger with a very high effective thermal conductivity. For a deeper understanding of the reaction kinetics at lower temperatures, single catalytic coated heat pipes are studied in a flow reactor. The development of a modular small-scale PAR model is then based on a test series with cooled catalyst sheets. Finally, the PAR model is tested inside a pressure vessel under boundary conditions similar to a real NPP. The experiments show, that the temperatures of the cooled catalytic sheets stay significantly below the temperature of the uncooled sheets and below the ignition temperature of the gas mixture under any set boundary conditions, although no significant reduction of the conversion efficiency can be observed. As a last point, a mathematical model of the reaction kinetics of the recombination process as well as a model of the fluid dynamic and thermohydraulic processes in a heat pipe are developed with the data obtained from the experiments.

  7. Childhood Pars Planitis; Clinical Features and Outcomes

    Directory of Open Access Journals (Sweden)

    Homayoon Nikkhah

    2011-01-01

    Full Text Available Purpose: To evaluate the demographic and clinical features of childhood pars planitis, and to determine the therapeutic and visual outcomes of the disease. Methods: Medical records of pediatric patients (less than 16 years of age at diagnosis with pars planitis and at least 6 months of follow-up who were referred to Labbafinejad Medical Center, Tehran, Iran over a 22 year period were reviewed. Results: Overall, 117 eyes of 61 patients including 51 (83.6% male subjects were included. Mean age at the time of diagnosis was 7.8΁3.2 (range, 3-16 years. Mean best corrected visual acuity (BCVA was 0.88΁0.76 logMAR at presentation which improved to 0.39΁0.51 logMAR at final visit (P<0.001. Endotheliitis was present in 23 (19.6% eyes and was significantly more prevalent in subjects younger than 9 years (P=0.025. Cataract formation (41.9% and cystoid macular edema (19.7% were the most prevalent complications. Univariate regression analysis showed that better baseline visual acuity (OR=0.38, 95%CI 0.21-0.70, P=0.002, age older than 5 years at disease onset (OR=0.36, 95%CI 0.14-0.9, P=0.029, absence of endotheliitis (OR=0.39, 95%CI 0.15-0.99, P=0.047 and female gender (OR=3.77, 95%CI 1.03-13.93, P=0.046 were significantly associated with final BCVA of 20/40 or better. Conclusion: Childhood pars planitis was much more common among male subjects. Endotheliitis may be a sign of inflammation spillover and is more prevalent in younger patients. Visual prognosis is favorable in most patients with appropriate treatment.

  8. Antenna for passive RFID tags

    Science.gov (United States)

    Schiopu, Paul; Manea, Adrian; Cristea, Ionica; Grosu, Neculai; Vladescu, Marian; Craciun, Anca-Ileana; Craciun, Alexandru

    2015-02-01

    Minuscule devices, called RFID tags are attached to objects and persons and emit information which positioned readers may capture wirelessly. Many methods of identification have been used, but that of most common is to use a unique serial number for identification of person or object. RFID tags can be characterized as either active or passive [1,2]. Traditional passive tags are typically in "sleep" state until awakened by the reader's emitted field. In passive tags, the reader's field acts to charge the capacitor that powers the badge and this can be a combination of antenna and barcodes obtained with SAW( Surface Acoustic Wave) devices [1,2,3] . The antenna in an RFID tag is a conductive element that permits the tag to exchange data with the reader. The paper contribution are targeted to antenna for passive RFID tags. The electromagnetic field generated by the reader is somehow oriented by the reader antenna and power is induced in the tag only if the orientation of the tag antenna is appropriate. A tag placed orthogonal to the reader yield field will not be read. This is the reason that guided manufacturers to build circular polarized antenna capable of propagating a field that is alternatively polarized on all planes passing on the diffusion axis. Passive RFID tags are operated at the UHF frequencies of 868MHz (Europe) and 915MHz (USA) and at the microwave frequencies of 2,45 GHz and 5,8 GHz . Because the tags are small dimensions, in paper, we present the possibility to use circular polarization microstrip antenna with fractal edge [2].

  9. Surface Passivation in Empirical Tight Binding

    Science.gov (United States)

    He, Yu; Tan, Yaohua; Jiang, Zhengping; Povolotskyi, Michael; Klimeck, Gerhard; Kubis, Tillmann

    2016-03-01

    Empirical Tight Binding (TB) methods are widely used in atomistic device simulations. Existing TB methods to passivate dangling bonds fall into two categories: 1) Method that explicitly includes passivation atoms is limited to passivation with atoms and small molecules only. 2) Method that implicitly incorporates passivation does not distinguish passivation atom types. This work introduces an implicit passivation method that is applicable to any passivation scenario with appropriate parameters. This method is applied to a Si quantum well and a Si ultra-thin body transistor oxidized with SiO2 in several oxidation configurations. Comparison with ab-initio results and experiments verifies the presented method. Oxidation configurations that severely hamper the transistor performance are identified. It is also shown that the commonly used implicit H atom passivation overestimates the transistor performance.

  10. Analysis method for the design of a hydrogen mitigation system with passive autocatalytic recombiners in OPR-1000

    Energy Technology Data Exchange (ETDEWEB)

    Kim, C-H.; Sung, J-J.; Ha, S-J. [Korea Hydro and Nuclear Power Co. Ltd., Central Research Inst., Daejeon (Korea, Republic of); Yeo, I-S. [KEPCO Engineering and Construction Co. Ltd, Gyeonggi-do (Korea, Republic of)

    2014-07-01

    The importance of hydrogen safety in nuclear power plants has been emphasized especially after the Fukushima accident in Japan. A passive autocatalytic recombiner (PAR) is considered as a viable option for the mitigation of hydrogen risk because of its passive operation for hydrogen removal. This paper presents a licensed hydrogen analysis method of OPR-1000, a 1,000MWe Korea standardized pressurized water reactor with a large dry containment, to determine the capacity and locations of PARs for the design of a hydrogen mitigation system with PAR. Various accident scenarios have been adopted considering important event sequences from a combination of probabilistic methods, deterministic methods and sound engineering judgment. A MAAP 4.0.6+ with a multi-compartment model is used as an analysis tool with conservative hydrogen generation and removal models. The detailed analyses are performed for selected severe accident scenarios including sensitivity analysis with/without operations of various safety systems. The possibility of global flame acceleration (FA) and deflagration-to-detonation transient (DDT) are assessed with sigma (flame acceleration potential) and 7-lambda (DDT potential) criterion. It is concluded that the newly designed hydrogen mitigation system with twenty-four (24) PARs can effectively remove hydrogen in the containment atmosphere and prevent global FA and DDT. (author)

  11. Passivation Of High-Temperature Superconductors

    Science.gov (United States)

    Vasquez, Richard P.

    1991-01-01

    Surfaces of high-temperature superconductors passivated with native iodides, sulfides, or sulfates formed by chemical treatments after superconductors grown. Passivating compounds nearly insoluble in and unreactive with water and protect underlying superconductors from effects of moisture. Layers of cuprous iodide and of barium sulfate grown. Other candidate passivating surface films: iodides and sulfides of bismuth, strontium, and thallium. Other proposed techniques for formation of passivating layers include deposition and gas-phase reaction.

  12. Passive Scalar Evolution in Peripheral Region

    OpenAIRE

    Lebedev, V. V.; Turitsyn, K. S.

    2003-01-01

    We consider evolution of a passive scalar (concentration of pollutants or temperature) in a chaotic (turbulent) flow. A universal asymptotic behavior of the passive scalar decay (homogenization) related to peripheral regions (near walls) is established. The passive scalar moments and its pair correlation function in the peripheral region are analyzed. A special case investigated in our paper is the passive scalar decay along a pipe.

  13. Exploring The Limits Of Variational Passive Microwave Retrievals

    Science.gov (United States)

    Duncan, David Ian

    Passive microwave observations from satellite platforms constitute one of the most important data records of the global observing system. Operational since the late 1970s, passive microwave data underpin climate records of precipitation, sea ice extent, water vapor, and more, and contribute significantly to numerical weather prediction via data assimilation. Detailed understanding of the observation errors in these data is key to maximizing their utility for research and operational applications alike. However, the treatment of observation errors in this data record has been lacking and somewhat divergent when considering the retrieval and data assimilation communities. In this study, some limits of passive microwave imager data are considered in light of more holistic treatment of observation errors. A variational retrieval, named the CSU 1DVAR, was developed for microwave imagers and applied to the GMI and AMSR2 sensors for ocean scenes. Via an innovative method to determine forward model error, this retrieval accounts for error covariances across all channels used in the iteration. This improves validation in more complex scenes such as high wind speed and persistently cloudy regimes. In addition, it validates on par with a benchmark dataset without any tuning to in-situ observations. The algorithm yields full posterior error diagnostics and its physical forward model is applicable to other sensors, pending intercalibration. This retrieval is used to explore the viability of retrieving parameters at the limits of the available information content from a typical microwave imager. Retrieval of warm rain, marginal sea ice, and falling snow are explored with the variational retrieval. Warm rain retrieval shows some promise, with greater sensitivity than operational GPM algorithms due to leveraging CloudSat data and accounting for drop size distribution variability. Marginal sea ice is also detected with greater sensitivity than a standard operational retrieval

  14. Accouchement par forceps: indications et pronostic materno-foetal ...

    African Journals Online (AJOL)

    L'accouchement par voie basse, peut être parfois compromis par des facteurs maternels, foetaux ou materno-foetaux nécessitant des moyens thérapeutiques comme le forceps pour achever l'accouchement par voie naturelle. Le forceps, une méthode qui n'est pas sans risque pour la mère et le nouveau-né. Nous avons ...

  15. Two or three decades of passive directions

    International Nuclear Information System (INIS)

    Cook, J.

    1995-01-01

    This paper presents an overview of the direction of passive solar architecture. The topics of the paper include design temperatures for buildings, active vs passive, fuel vs philosophy, engineering vs architecture, the thermal scale: heating vs cooling, fuel subsidies, divergent practices, sustainability, lighting, health, the place of passive technology

  16. Active house concept versus passive House

    NARCIS (Netherlands)

    Zeiler, W.; Boxem, G.; Vehler, R.; Verhoeven, M.; Fremouw, M.

    2009-01-01

    The passive house concept is the present trend in energy efficient sustainable dwellings. Within the passive house concept every effort is made to minimize the energy use. Substantial savings can be achieved by passive energy systems, especially natural ventilation, summer shading and winter solar

  17. Innovative solutions in passive house details

    NARCIS (Netherlands)

    Mlecnik, E.; Hilderson, W.

    2008-01-01

    For the realization of the first passive house demonstration projects in Belgium, passive houses were requested by convinced clients, designed by architects with experience in low energy building, and built by contractors with a feeling for working in building teams. These first passive house

  18. A Lexical Approach to Passive in ESL.

    Science.gov (United States)

    Marshall, Fred

    Dissatisfaction with the standard transformational grammar approach to teaching passive voice sentences gave rise to the method developed. It is based on the framework of a lexical-functional grammar, which claims that both active and passive sentences are base-generated, and that both active and passive verb forms occur in the lexicon. It would…

  19. Integrated hydrogen control solutions for severe accidents using passive autocatalytic recombiners

    International Nuclear Information System (INIS)

    Bauer, M.; Tietsch, W.; Sabate Farnos, R.

    2012-01-01

    In a severe accident or a beyond-design-basis-accident, the reaction of water with zirconium alloy cladding, radiolysis of water, corium-concrete reactions and other corrosion phenomena generate hydrogen (H2). The detonation of this H2 in containment or in auxiliary buildings can result in damage to structures or loss of containment integrity. Identifying the generation and special distribution of hydrogen and controlling its concentration with Passive Autocatalytic Recombiners (PARs) solves this concern. Westinghouse's approach for hydrogen management starts by defining the quantities and transport/distribution of H 2 in-containment and out of containment with analysis tools such as MAAP, MELCOR, GASFLOW or FATE. Based on the results of these analyses, an optimized H2 Control Strategy is proposed in terms of number and location of PARs, and efficient integration with other H 2 management devices like e.g. existing igniters, H 2 monitors, etc.

  20. Traffic classification with passive measurement

    OpenAIRE

    Pham, Hoang Phong

    2005-01-01

    Abstract This is a master thesis from a collaboration between Oslo University College and Uninett Research. Uninett have a passive monitoring device on a 2.5 Gbps backbone link between Trondheim and Narvik. They uses measurement with optical splitters and specialized measuring interfaces to trace traffic with Gigabit speed. We would like to investigate the structure and patterns in these data. It is of special interest to classify the traffic belonging to different services and protocols. ...

  1. EP1000 passive plant description

    International Nuclear Information System (INIS)

    Saiu, G.

    1999-01-01

    In 1994, a group of European Utilities, together with Westinghouse and its Industrial Partner GENESI (an Italian consortium including ANSALDO and FIAT), initiated a program designated EPP (European Passive Plant) to evaluate Westinghouse Passive Nuclear Plant Technology for application in Europe. In Phase I of the European Passive Plant Program which was completed in 1996, a 1000 MWe passive plant reference design (EP1000) was established which conforms to the European Utility Requirements (EUR) and is expected to meet the European Safety Authorities requirements. Phase 2 of the program was initiated in 1997 with the objective of developing the Nuclear Island design details and performing supporting analyses to start development of Safety Case Report (SCR) for submittal to European Licensing Authorities. The first part of Phase 2, 'Design Definition' phase (Phase 2A) will be completed at the end of 1998, the main efforts being design definition of key systems and structures, development of the Nuclear Island layout, and performing preliminary safety analyses to support design efforts. The second part, 'Phase 2B', includes both the analyses and evaluations required to demonstrate the adequacy of the design, and to support the preparation of Safety Case Report. The second part of Phase 2 of the program will start at the beginning of 1999 and will be completed in the 2001. Incorporation of the EUR has been a key design requirement for the EP1000 from the beginning of the program. Detailed design solutions to meet the EUR have been defined and the safety approach has also been developed based on the EUR guidelines. This paper integrates and updates the plant description reported in the IAEA TECDOC-968. The most significant developments of the EP1000 plant design during Phase 2A of the EPP program are described and reference is made to the key design requirements set by the EUR Rev. B document. (author)

  2. Active and Passive Hybrid Sensor

    Science.gov (United States)

    Carswell, James R.

    2010-01-01

    A hybrid ocean wind sensor (HOWS) can map ocean vector wind in low to hurricane-level winds, and non-precipitating and precipitating conditions. It can acquire active and passive measurements through a single aperture at two wavelengths, two polarizations, and multiple incidence angles. Its low profile, compact geometry, and low power consumption permits installation on air craft platforms, including high-altitude unmanned aerial vehicles (UAVs).

  3. Alternative to Nitric Acid Passivation

    Science.gov (United States)

    Kessel, Kurt R.

    2016-01-01

    Corrosion is an extensive problem that affects the National Aeronautics and Space Administration (NASA) and European Space Agency (ESA). The deleterious effects of corrosion result in steep costs, asset downtime affecting mission readiness, and safety risks to personnel. It is vital to reduce corrosion costs and risks in a sustainable manner. The primary objective of this effort is to qualify citric acid as an environmentally-preferable alternative to nitric acid for passivation of stainless steel alloys.

  4. Interior design for passive solar homes

    Energy Technology Data Exchange (ETDEWEB)

    Breen, J. C.

    1981-07-01

    The increasing emphasis on refinement of passive solar systems has brought recognition to interior design as an integral part of passive solar architecture. Interior design can be used as a finetuning tool minimizing many of the problems associated with passive solar energy use in residential buildings. In addition, treatment of interior space in solar model homes may be a prime factor in determining sales success. A new style of interior design is evolving in response to changes in building form incorporating passive solar design features. The psychology behind passive solar architecture is reflected in interiors, and selection of interior components increasingly depends on the functional suitability of various interior elements.

  5. Interior design for passive solar homes

    Science.gov (United States)

    Breen, J. C.

    1981-07-01

    The increasing emphasis on refinement of passive solar systems brought recognition to interior design as an integral part of passive solar architecture. Interior design can be used as a finetuning tool minimizing many of the problems associated with passive solar energy use in residential buildings. In addition, treatment of interior space in solar model homes may be a prime factor in determining sales success. A new style of interior design is evolving in response to changes in building from incorporating passive solar design features. The psychology behind passive solar architecture is reflected in interiors, and selection of interior components increasingly depends on the functional suitably of various interior elements.

  6. Degradation of materials and passivity

    International Nuclear Information System (INIS)

    Meisel, W.

    1997-01-01

    Demanding for a reduction in materials degradation is a serious problem all over the world. Moessbauer spectroscopy (MS) is, among others, a very valuable tool to follow many degradation processes. Evidently, Fe is the most important Moessbauer element considering the overall presence of iron in everyday life. MS may contribute to our knowledge about nearly all fields of materials degradation, chemical, mechanical, thermal, irradiative, etc. Following some general lines, corrosion is considered in particular. MS is applicable to investigate the bulk of materials as well as their surface layers with an information depth of ca. 250 nm. In general, it has to be applied as a surface sensitive method in combination with other relevant methods in order to get a detailed insight into ongoing processes. Some examples have been selected to elucidate the application of MS in this field. Another class of examples concerns attempts to prevent corrosion, i.e., the application of coatings and transforming chemicals. A very effective and most natural way to reduce corrosion is the passivation of materials. The effect of passive layers and their destruction by environmental influences are discussed using results of MS and related methods. It is outlined that passivity is not restricted to chemically treated metals but can be considered as a general concept for preventing different kinds of materials from degradation. (orig.)

  7. Passive infrared motion sensing technology

    International Nuclear Information System (INIS)

    Doctor, A.P.

    1994-01-01

    In the last 10 years passive IR based (8--12 microns) motion sensing has matured to become the dominant method of volumetric space protection and surveillance. These systems currently cost less than $25 to produce and yet use traditionally expensive IR optics, filters, sensors and electronic circuitry. This IR application is quite interesting in that the volumes of systems produced and the costs and performance level required prove that there is potential for large scale commercial applications of IR technology. This paper will develop the basis and principles of operation of a staring motion sensor system using a technical approach. A model for the motion of the target is developed and compared to the background. The IR power difference between the target and the background as well as the optical requirements are determined from basic principles and used to determine the performance of the system. Low cost reflective and refractive IR optics and bandpass IR filters are discussed. The pyroelectric IR detector commonly used is fully discussed and characterized. Various schemes for ''false alarms'' have been developed and are also explained. This technology is also used in passive IR based motion sensors for other applications such as lighting control. These applications are also discussed. In addition the paper will discuss new developments in IR surveillance technology such as the use of linear motion sensing arrays. This presentation can be considered a ''primer'' on the art of Passive IR Motion Sensing as applied to Surveillance Technology

  8. The passive of reflexive verbs in Icelandic

    Directory of Open Access Journals (Sweden)

    Hlíf Árnadóttir

    2011-10-01

    Full Text Available The Reflexive Passive in Icelandic is reminiscent of the so-called New Passive (or New Impersonal in that the oblique case of a passivized object NP is preserved. As is shown by recent surveys, however, speakers who accept the Reflexive Passive do not necessarily accept the New Passive, whereas conversely, speakers who accept the New Passive do also accept the Reflexive Passive. Based on these results we suggest that there is a hierarchy in the acceptance of passive sentences in Icelandic, termed the Passive Acceptability Hierarchy. The validity of this hierarchy is confirmed by our diachronic corpus study of open access digital library texts from Icelandic journals and newspapers dating from the 19th and 20th centuries (tímarit.is. Finally, we sketch an analysis of the Reflexive Passive, proposing that the different acceptability rates of the Reflexive and New Passives lie in the argument status of the object. Simplex reflexive pronouns are semantically dependent on the verbs which select them, and should therefore be analyzed as syntactic arguments only, and not as semantic arguments of these verbs.

  9. PAR1 activation affects the neurotrophic properties of Schwann cells.

    Science.gov (United States)

    Pompili, Elena; Fabrizi, Cinzia; Somma, Francesca; Correani, Virginia; Maras, Bruno; Schininà, Maria Eugenia; Ciraci, Viviana; Artico, Marco; Fornai, Francesco; Fumagalli, Lorenzo

    2017-03-01

    Protease-activated receptor-1 (PAR1) is the prototypic member of a family of four G-protein-coupled receptors that signal in response to extracellular proteases. In the peripheral nervous system, the expression and/or the role of PARs are still poorly investigated. High PAR1 mRNA expression was found in the rat dorsal root ganglia and the signal intensity of PAR1 mRNA increased in response to sciatic nerve transection. In the sciatic nerve, functional PAR1 receptor was reported at the level of non-compacted Schwann cell myelin microvilli of the nodes of Ranvier. Schwann cells are the principal population of glial cells of the peripheral nervous system which myelinate axons playing an important role during axonal regeneration and remyelination. The present study was undertaken in order to determine if the activation of PAR1 affects the neurotrophic properties of Schwann cells. Our results suggest that the stimulation of PAR1 could potentiate the Schwann cell ability to favour nerve regeneration. In fact, the conditioned medium obtained from Schwann cell cultures challenged with a specific PAR1 activating peptide (PAR1 AP) displays increased neuroprotective and neurotrophic properties with respect to the culture medium from untreated Schwann cells. The proteomic analysis of secreted proteins in untreated and PAR1 AP-treated Schwann cells allowed the identification of factors differentially expressed in the two samples. Some of them (such as macrophage migration inhibitory factor, matrix metalloproteinase-2, decorin, syndecan 4, complement C1r subcomponent, angiogenic factor with G patch and FHA domains 1) appear to be transcriptionally regulated after PAR1 AP treatment as shown by RT-PCR. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. A comparison of titers of anti-Brucella antibodies of naturally infected and healthy vaccinated cattle by standard tube agglutination test, microtiter plate agglutination test, indirect hemagglutination assay, and indirect enzyme-linked immunosorbent assay

    Directory of Open Access Journals (Sweden)

    Anju Mohan

    2016-07-01

    Full Text Available Aim: We determined the antibody response in cattle naturally infected with brucellosis and normal healthy adult cattle vaccinated during calf hood with strain 19. Materials and Methods: The antibody titers were measured by standard tube agglutination test (STAT, microtiter plate agglutination test (MAT, indirect hemagglutination assay (IHA, and indirect enzyme-linked immunosorbent assay (iELISA as per standard protocols. Results: The mean STAT titers were 1.963±0.345 in infected cattle and 1.200±0.155 in healthy vaccinated cattle. The difference was extremely significant (p<0.0001. The mean MAT titers were 2.244±0.727 in infected cattle and 1.200±0.155 in healthy vaccinated cattle. The difference was very significant (p<0.005. The mean IHA titers in infected cattle were 2.284±0.574, and those in healthy vaccinated cattle were 1.200±0.155. The difference was extremely significant (p=0.0002. However, the difference in mean iELISA titers of infected cattle (1.3678±0.014 and healthy vaccinated cattle (1.367±0.014 was non-significant. The infected animals showed very high titers of agglutinating antibodies compared to the vaccinated animals. However, it cannot be ascertained whether these antibodies are due to vaccine or response to infection. Since the infected animals had been vaccinated earlier, the current infection may suggest that vaccination was unable to induce protective levels of antibody. The heightened antibody response after infection may also indicate a secondary immune response to the antigens common to the vaccine strain and wild Brucella organisms. Conclusion: The brucellosis infected animals showed very high titers of agglutinating antibodies compared to the vaccinated animals.

  11. Taare Zameen Par and dyslexic savants.

    Science.gov (United States)

    Chakravarty, Ambar

    2009-04-01

    The film Taare Zameen Par (Stars upon the Ground) portrays the tormented life at school and at home of a child with dyslexia and his eventual success after his artistic talents are discovered by his art teacher at the boarding school. The film hints at a curious neurocognitive phenomenon of creativity in the midst of language disability, as exemplified in the lives of people like Leonardo da Vinci and Albert Einstein, both of whom demonstrated extraordinary creativity even though they were probably affected with developmental learning disorders. It has been hypothesized that a developmental delay in the dominant hemisphere most likely 'disinhibits' the nondominant parietal lobe, unmasking talents-artistic or otherwise-in some such individuals. It has been suggested that, in remedial training, children with learning disorders be encouraged to develop such hidden talents to full capacity, rather than be subjected to the usual overemphasis on the correction of the disturbed coded symbol operations.

  12. Soudage de bois feuillus par friction rotationnelle

    OpenAIRE

    Belleville, Benoît

    2012-01-01

    Les différentes colles utilisées actuellement par l’industrie du meuble au Canada nécessitent des temps de polymérisation constituant un goulot dans la production des meubles et limitant l’atteinte de la production unitaire. Ces adhésifs synthétiques généralement issus de la pétrochimie nécessitent énormément d’énergie lors de leur confection. L’utilisation de connecteurs métalliques ou plastiques, quant à elle, limite les phases de découpage et sablage subséquentes. La présence d’adhésifs et...

  13. TMS suppression of right pars triangularis, but not pars opercularis, improves naming in aphasia

    Science.gov (United States)

    Naeser, Margaret A.; Martin, Paula I.; Theoret, Hugo; Kobayashi, Masahito; Fregni, Felipe; Nicholas, Marjorie; Tormos, Jose M.; Steven, Megan S.; Baker, Errol H.; Pascual-Leone, Alvaro

    2011-01-01

    This study sought to discover if an optimum 1 cm2 area in the non-damaged right hemisphere (RH) was present, which could temporarily improve naming in chronic, nonfluent aphasia patients when suppressed with repetitive transcranial magnetic stimulation (rTMS). Ten minutes of slow, 1 Hz rTMS was applied to suppress different RH ROIs in eight aphasia cases. Picture naming and response time (RT) were examined before, and immediately after rTMS. In aphasia patients, suppression of right pars triangularis (PTr) led to significant increase in pictures named, and significant decrease in RT. Suppression of right pars opercularis (POp), however, led to significant increase in RT, but no change in number of pictures named. Eight normals named all pictures correctly; similar to aphasia patients, RT significantly decreased following rTMS to suppress right PTr, versus right POp. Differential effects following suppression of right PTr versus right POp suggest different functional roles for these regions. PMID:21864891

  14. ParABS system in chromosome partitioning in the bacterium Myxococcus xanthus.

    Directory of Open Access Journals (Sweden)

    Antonio A Iniesta

    Full Text Available Chromosome segregation is an essential cellular function in eukaryotic and prokaryotic cells. The ParABS system is a fundamental player for a mitosis-like process in chromosome partitioning in many bacterial species. This work shows that the social bacterium Myxococcus xanthus also uses the ParABS system for chromosome segregation. Its large prokaryotic genome of 9.1 Mb contains 22 parS sequences near the origin of replication, and it is shown here that M. xanthus ParB binds preferentially to a consensus parS sequence in vitro. ParB and ParA are essential for cell viability in M. xanthus as in Caulobacter crescentus, but unlike in many other bacteria. Absence of ParB results in anucleate cells, chromosome segregation defects and loss of viability. Analysis of ParA subcellular localization shows that it clusters at the poles in all cells, and in some, in the DNA-free cell division plane between two chromosomal DNA masses. This ParA localization pattern depends on ParB but not on FtsZ. ParB inhibits the nonspecific interaction of ParA with DNA, and ParA colocalizes with chromosomal DNA only when ParB is depleted. The subcellular localization of ParB suggests a single ParB-parS complex localized at the edge of the nucleoid, next to a polar ParA cluster, with a second ParB-parS complex migrating after the replication of parS takes place to the opposite nucleoid edge, next to the other polar ParA cluster.

  15. Concerning the dynamic instability of actin homolog ParM

    International Nuclear Information System (INIS)

    Popp, David; Yamamoto, Akihiro; Iwasa, Mitsusada; Narita, Akihiro; Maeda, Kayo; Maeda, Yuichiro

    2007-01-01

    Using in vitro TIRF- and electron-microscopy, we reinvestigated the dynamics of native ParM, a prokaryotic DNA segregation protein and actin homolog. In contrast to a previous study, which used a cysteine ParM mutant, we find that the polymerization process of wild type ATP-ParM filaments consists of a polymerization phase and a subsequent steady state phase, which is dynamically unstable, like that of microtubules. We find that the apparent bidirectional polymerization of ParM, is not due to the intrinsic nature of this filament, but results from ParM forming randomly oriented bundles in the presence of crowding agents. Our results imply, that in the bacterium, ParM filaments spontaneously form bipolar bundles. Due to their intrinsic dynamic instability, ParM bundles can efficiently 'search' the cytoplasmic lumen for DNA, bind it equally well at the bipolar ends and segregate it approximately symmetrically, by the insertion of ParM subunits at either end

  16. The protein kinase SIK downregulates the polarity protein Par3

    DEFF Research Database (Denmark)

    Vanlandewijck, Michael; Dadras, Mahsa Shahidi; Lomnytska, Marta

    2018-01-01

    on Par3. Functionally, this mechanism impacts on tight junction downregulation. Furthermore, SIK contributes to the loss of epithelial polarity and examination of advanced and invasive human cancers of diverse origin displayed high levels of SIK expression and a corresponding low expression of Par3...

  17. Passive film growth on carbon steel and its nanoscale features at various passivating potentials

    International Nuclear Information System (INIS)

    Li, Yuan; Cheng, Y. Frank

    2017-01-01

    Highlights: • Imaged the topography of passivated steel at various film-forming potentials. • Characterized the nanoscale features of passive films. • Determined the composition of passive films formed at various potentials. - Abstract: In this work, the passivation and topographic sub-structure of passive films on a carbon steel in a carbonate/bicarbonate solution was characterized by electrochemical measurements, atomic force microscopy and X-ray photoelectron spectroscopy. When passivating at a potential near the active-passive transition, the film contains the mixture of Fe_3O_4, Fe_2O_3 and FeOOH, with numerous nanoscale features. As the film-forming potential shifts positively, the passive film becomes more compact and the nanoscale features disappear. When the film is formed at a passive potential where the oxygen evolution is enabled, the content of FeOOH in the film increases, resulting in an amorphous topography and reduced corrosion resistance.

  18. EFFECTS OF CHINESE HERBS ON THE HEMAGGLUTINATION ...

    African Journals Online (AJOL)

    USER

    commonly employed therapeutic methods in TCM include Chinese herbal medicine, acupuncture/moxibustion, diet therapy, mind/body exercises (Qigong and Tai Chi), and Tui Na (Chinese massage) (Lao, 1999). Herbal medicine has been an integral part of TCM for more than 2000 years. Many herbal formulations have ...

  19. Recombination in the human Pseudoautosomal region PAR1.

    Directory of Open Access Journals (Sweden)

    Anjali G Hinch

    2014-07-01

    Full Text Available The pseudoautosomal region (PAR is a short region of homology between the mammalian X and Y chromosomes, which has undergone rapid evolution. A crossover in the PAR is essential for the proper disjunction of X and Y chromosomes in male meiosis, and PAR deletion results in male sterility. This leads the human PAR with the obligatory crossover, PAR1, to having an exceptionally high male crossover rate, which is 17-fold higher than the genome-wide average. However, the mechanism by which this obligatory crossover occurs remains unknown, as does the fine-scale positioning of crossovers across this region. Recent research in mice has suggested that crossovers in PAR may be mediated independently of the protein PRDM9, which localises virtually all crossovers in the autosomes. To investigate recombination in this region, we construct the most fine-scale genetic map containing directly observed crossovers to date using African-American pedigrees. We leverage recombination rates inferred from the breakdown of linkage disequilibrium in human populations and investigate the signatures of DNA evolution due to recombination. Further, we identify direct PRDM9 binding sites using ChIP-seq in human cells. Using these independent lines of evidence, we show that, in contrast with mouse, PRDM9 does localise peaks of recombination in the human PAR1. We find that recombination is a far more rapid and intense driver of sequence evolution in PAR1 than it is on the autosomes. We also show that PAR1 hotspot activities differ significantly among human populations. Finally, we find evidence that PAR1 hotspot positions have changed between human and chimpanzee, with no evidence of sharing among the hottest hotspots. We anticipate that the genetic maps built and validated in this work will aid research on this vital and fascinating region of the genome.

  20. Diagnóstico sorológico de infecções por dengue e febre amarela em casos suspeitos no Estado do Pará, Brasil, 1999 Serological diagnosis of dengue and yellow fever infections in suspected cases from Pará State, Brazil, 1999

    Directory of Open Access Journals (Sweden)

    Tais Pinheiro de Araújo

    2002-12-01

    Full Text Available De junho a dezembro de 1999, foram coletadas 785 amostras de soro de pacientes com suspeita clínica de dengue e/ou febre amarela. Os pacientes foram atendidos nas unidades de saúde distribuídas pelas seis mesorregiões do Estado do Pará, Brasil. As amostras de soro foram testadas pelo método de inibição da hemaglutinação para detecção de anticorpos para Flavivirus e pelo ensaio imunoenzimático para detecção de imunoglobulina M para dengue e febre amarela. Das amostras coletadas, 563 (71,7% foram positivas pelo IH, e dentre estas 150 (26,6% foram positivas pelo ELISA-IgM. O vírus dengue foi responsável pela maioria das infecções recentes em todas as mesorregiões e os casos de febre amarela detectados neste estudo foram restritos às mesorregiões Marajó e Sudeste.From June to December 1999, 785 serum samples were obtained from patients clinically suspected of having dengue or yellow fever. The patients were referred by public health centers distributed within the six mesoregions of Pará State, Brazil. Serum samples were tested for Flavivirus antibodies by hemagglutination inhibition test and for dengue and yellow fever viruses by enzyme-linked immunosorbent assay for IgM detection. Of the sera collected, 563 (71.7% were positive by HI test and out of these 150 (26.6% were positive by ELISA-IgM. Dengue virus was responsible for most of the recent infections in all regions; yellow fever cases detected in the current study were restricted to the Marajó and Southeast regions.

  1. Hen egg yolk antibodies (IgY), production and use for passive immunization against bacterial enteric infections in chicken : a review

    OpenAIRE

    Chalghoumi, Raja; Beckers, Yves; Portetelle, Daniel; Thewis, André

    2009-01-01

    Les anticorps du jaune d’oeuf de poule (IgY), production et utilisation en immunisation passive contre les infections entériques bactériennes : une revue. Les infections entériques causées par Salmonella constituent un problème majeur de santé publique à travers le monde. Il est bien connu que la volaille, en particulier le poulet de chair, constitue le principal réservoir pour ce pathogène zoonotique. Par conséquent, la prévention et la surveillance de Salmonella au cours de la phase d’éleva...

  2. The passive-aggressive organization.

    Science.gov (United States)

    Kaplan, Robert S; Norton, David P

    2005-10-01

    Passive-aggressive organizations are friendly places to work: People are congenial, conflict is rare, and consensus is easy to reach. But, at the end of the day, even the best proposals fail to gain traction, and a company can go nowhere so imperturbably that it's easy to pretend everything is fine. Such companies are not necessarily saddled with mulishly passive-aggressive employees. Rather, they are filled with mostly well-intentioned people who are the victirms of flawed processes and policies. Commonly, a growing company's halfhearted or poorly thought-out attempts to decentralize give rise to multiple layers of managers, whose authority for making decisions becomes increasingly unclear. Some managers, as a result, hang back, while others won't own up to the calls they've made, inviting colleagues to second-guess or overturn the decisions. In such organizations, information does not circulate freely, and that makes it difficult for workers to understand the impact of their actions on company performance and for managers to correctly appraise employees' value to the organization. A failure to accurately match incentives to performance stifles initiative, and people do just enough to get by. Breaking free from this pattern is hard; a long history of seeing corporate initiatives ignored and then fade away tends to make people cynical. Often it's best to bring in an outsider to signal that this time things will be different. He or she will need to address every obstacle all at once: clarify decision rights; see to it that decisions stick; and reward people for sharing information and adding value, not for successfully negotiating corporate politics. If those steps are not taken, it's only a matter of time before the diseased elements of a passive-aggressive organization overwhelm the remaining healthy ones and drive the company into financial distress.

  3. Architectural Qualities in Passive Houses

    DEFF Research Database (Denmark)

    Brunsgaard, Camilla

    2012-01-01

    that it is possible to build this type of houses, but the knowledge and discussion about the architectural quality in the buildings is hardly present. The question is if the strategies for optimising energy use and indoor environment collide with the architectural qualities of buildings. This paper brings forth...... this discussion based in literature and four case studies. The paper highlights cases on how passive strategies for optimising energy use and indoor environment affect, restrict, inspire or create possibilities for the architectural expression and there through the architectural quality of the building....

  4. Passive Containment DataSet

    Science.gov (United States)

    This data is for Figures 6 and 7 in the journal article. The data also includes the two EPANET input files used for the analysis described in the paper, one for the looped system and one for the block system.This dataset is associated with the following publication:Grayman, W., R. Murray , and D. Savic. Redesign of Water Distribution Systems for Passive Containment of Contamination. JOURNAL OF THE AMERICAN WATER WORKS ASSOCIATION. American Water Works Association, Denver, CO, USA, 108(7): 381-391, (2016).

  5. Passive longitudinal phase space linearizer

    Directory of Open Access Journals (Sweden)

    P. Craievich

    2010-03-01

    Full Text Available We report on the possibility to passively linearize the bunch compression process in electron linacs for the next generation x-ray free electron lasers. This can be done by using the monopole wakefields in a dielectric-lined waveguide. The optimum longitudinal voltage loss over the length of the bunch is calculated in order to compensate both the second-order rf time curvature and the second-order momentum compaction terms. Thus, the longitudinal phase space after the compression process is linearized up to a fourth-order term introduced by the convolution between the bunch and the monopole wake function.

  6. Measurement and Treatment of Passive Muscle Stiffness

    DEFF Research Database (Denmark)

    Kirk, Henrik

    , which aimed to investigate: 1) The development of a clinical method to evaluate and distinguish neural (reflex mediated stiffness) and non-neural (passive muscle stiffness) components of muscle stiffness in adults with CP by objective and reliable measurements. 2) The association between increased...... and reliability of the method, and argue for the use of the method in the clinical practice. The device is able to distinguish between passive muscle stiffness and reflex-mediated stiffness in subjects with CP. It shows good high intrarater and interrater reliability in evaluation of passive muscle stiffness...... to measure muscle stiffness, and distinguish between passive muscle stiffness and reflex-mediated stiffness. Furthermore, it is a reliable device to measure changes in passive ROM. Treatment of passive muscle stiffness should be directed towards intense training, comprising many repetitions with a functional...

  7. Forekomsten af passiv rygning i Danmark

    DEFF Research Database (Denmark)

    Kristensen, T S; Møller, L; Holstein, B E

    1990-01-01

    The occurrence of passive smoking in the adult population in Denmark has not been described previously. This article publishes data from three investigations all of which were carried out in 1987. One was an interview investigation of a random section of the Danish population carried out by the D...... inconvenienced by passive smoking at work and a corresponding fraction had taken steps to reduce the extent of passive smoking in their daily life. Udgivelsesdato: 1990-Aug-27...... showed consistent results as regards the occurrence of passive smoking among adult Danes. About 12% of non-smokers were exposed to passive smoking for at least eight hours and 40% for at least one hour daily. Altogether 73% were exposed to passive smoking daily. About one third of the non-smokers were...

  8. Columbia County Habitat for Humanity Passive Townhomes

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2016-03-01

    Columbia County Habitat for Humanity (CCHH) (New York, Climate Zone 5A) built a pair of townhomes to Passive House Institute U.S. (PHIUS+ 2015) criteria to explore approaches for achieving Passive House performance (specifically with respect to exterior wall, space-conditioning, and ventilation strategies) within the labor and budget context inherent in a Habitat for Humanity project. CCHH’s goal is to eventually develop a cost-justified Passive House prototype design for future projects.

  9. Passive Nuclear Plants Program (UPDATE)

    International Nuclear Information System (INIS)

    Chimeno, M. A.

    1998-01-01

    The light water passive plants program (PCNP), today Advanced Nuclear Power Plants Program (PCNA), was constituted in order to reach the goals of the Spanish Electrical Sector in the field of advanced nuclear power plants, optimize the efforts of all Spanish initiatives, and increase joint presence in international projects. The last update of this program, featured in revision 5th of the Program Report, reflects the consolidation of the Spanish sector's presence in International programs of the advanced power plants on the basis of the practically concluded American ALWR program. Since the beginning of the program , the PCNP relies on financing from the Electrical sector, Ocide, SEPI-Endesa, Westinghouse, General Electric, as well as from the industrial cooperators, Initec, UTE (Initec- Empresarios Agrupados), Ciemat, Enusa, Ensa and Tecnatom. The program is made up of the following projects, already concluded: - EPRI's Advanced Light Water Plants Certification Project - Westinghouse's AP600 Project - General Electric's SBWR Project (presently paralyzed) and ABWR project Currently, the following project are under development, at different degrees of advance: - EPP project (European Passive Plant) - EBWR project (European Advanced Boiling Water Reactor)

  10. A Portable Passive Physiotherapeutic Exoskeleton

    Directory of Open Access Journals (Sweden)

    Dasheek Naidu

    2012-10-01

    Full Text Available The public healthcare system in South Africa is in need of urgent attention in no small part because there has been an escalation in the number of stroke victims which could be due to the increase in hypertension in this urbanizing society. There is a growing need for physiotherapists and occupational therapists in the country, which is further hindered by the division between urban and rural areas. A possible solution is a portable passive physiotherapeutic exoskeleton device. The exoskeleton device has been formulated to encapsulate methodologies that enable the anthropomorphic integration between a biological and mechatronic limb. A physiotherapeutic mechanism was designed to be portable and adjustable, without limiting the spherical motion and workspace of the human arm. The exoskeleton was designed to be portable in the sense that it could be transported geographically. It is a complete device allowing for motion in the shoulder, elbow, wrist and hand joints. The inverse kinematics was solved iteratively via the Damped Least Squares (DLS method. The electronic and computer system allowed for professional personnel to either change an individual joint or a combination of joints angles via the kinematic models. A ramp PI controller was established to provide a smooth response to simulate the passive therapy motion.

  11. Liberal theory of passive citizenship

    Directory of Open Access Journals (Sweden)

    Salatić Stevan

    2013-01-01

    Full Text Available In this seminar paper I will focus on the analysis of liberal theory of citizenship. The focus of the study will be on the liberal-communitarian dispute in the theory of citizenship, with main ideas of the most important representatives of liberal discourse in the field of citizenship also being discussed. I will look more closely at the ideas of T.H. Marshall, as the most significant writer of liberal orthodoxy in the second half of the twentieth century, his contribution to liberal theory of passive citizenship, but I will also deal with the ideas of his biggest critics, both from the aspect of liberalism and from the aspect of communitarianism, including Anthony Giddens, Claus Offe, Michael Mann, Barrington Moore and Brian Turner. The emphasis will be on Marshall's term 'conquest of citizenship', as well as on the derivation of various theories of state from the obtained rights achieved through the expansion of the concept of citizenship. Finally, I will say something about modern obstacles to theories of passive citizenship derived from the communitarian school.

  12. Passive propulsion in vortex wakes

    Science.gov (United States)

    Beal, D. N.; Hover, F. S.; Triantafyllou, M. S.; Liao, J. C.; Lauder, G. V.

    A dead fish is propelled upstream when its flexible body resonates with oncoming vortices formed in the wake of a bluff cylinder, despite being well outside the suction region of the cylinder. Within this passive propulsion mode, the body of the fish extracts sufficient energy from the oncoming vortices to develop thrust to overcome its own drag. In a similar turbulent wake and at roughly the same distance behind a bluff cylinder, a passively mounted high-aspect-ratio foil is also shown to propel itself upstream employing a similar flow energy extraction mechanism. In this case, mechanical energy is extracted from the flow at the same time that thrust is produced. These results prove experimentally that, under proper conditions, a body can follow at a distance or even catch up to another upstream body without expending any energy of its own. This observation is also significant in the development of low-drag energy harvesting devices, and in the energetics of fish dwelling in flowing water and swimming behind wake-forming obstacles.

  13. Utility requirements for advanced LWR passive plants

    International Nuclear Information System (INIS)

    Yedidia, J.M.; Sugnet, W.R.

    1992-01-01

    LWR Passive Plants are becoming an increasingly attractive and prominent option for future electric generating capacity for U.S. utilities. Conceptual designs for ALWR Passive Plants are currently being developed by U.S. suppliers. EPRI-sponsored work beginning in 1985 developed preliminary conceptual designs for a passive BWR and PWR. DOE-sponsored work from 1986 to the present in conjunction with further EPRI-sponsored studies has continued this development to the point of mature conceptual designs. The success to date in developing the ALWR Passive Plant concepts has substantially increased utility interest. The EPRI ALWR Program has responded by augmenting its initial scope to develop a Utility Requirements Document for ALWR Passive Plants. These requirements will be largely based on the ALWR Utility Requirements Document for Evolutionary Plants, but with significant changes in areas related to the passive safety functions and system configurations. This work was begun in late 1988, and the thirteen-chapter Passive Plant Utility Requirements Document will be completed in 1990. This paper discusses the progress to date in developing the Passive Plant requirements, reviews the top-level requirements, and discusses key issues related to adaptation of the utility requirements to passive safety functions and system configurations. (orig.)

  14. Multiple mechanisms quench passive spiral galaxies

    Science.gov (United States)

    Fraser-McKelvie, Amelia; Brown, Michael J. I.; Pimbblet, Kevin; Dolley, Tim; Bonne, Nicolas J.

    2018-02-01

    We examine the properties of a sample of 35 nearby passive spiral galaxies in order to determine their dominant quenching mechanism(s). All five low-mass (M⋆ environments. We postulate that cluster-scale gas stripping and heating mechanisms operating only in rich clusters are required to quench low-mass passive spirals, and ram-pressure stripping and strangulation are obvious candidates. For higher mass passive spirals, while trends are present, the story is less clear. The passive spiral bar fraction is high: 74 ± 15 per cent, compared with 36 ± 5 per cent for a mass, redshift and T-type matched comparison sample of star-forming spiral galaxies. The high mass passive spirals occur mostly, but not exclusively, in groups, and can be central or satellite galaxies. The passive spiral group fraction of 74 ± 15 per cent is similar to that of the comparison sample of star-forming galaxies at 61 ± 7 per cent. We find evidence for both quenching via internal structure and environment in our passive spiral sample, though some galaxies have evidence of neither. From this, we conclude no one mechanism is responsible for quenching star formation in passive spiral galaxies - rather, a mixture of mechanisms is required to produce the passive spiral distribution we see today.

  15. Inherent/passive safety for fusion

    International Nuclear Information System (INIS)

    Piet, S.J.

    1986-06-01

    The concept of inherent or passive passive safety for fusion energy is explored, defined, and partially quantified. Four levels of safety assurance are defined, which range from true inherent safety to passive safety to protection via active engineered safeguard systems. Fusion has the clear potential for achieving inherent or passive safety, which should be an objective of fusion research and design. Proper material choice might lead to both inherent safety and high mass power density, improving both safety and economics. When inherent safety is accomplished, fusion will be well on the way to achieving its ultimate potential and to be truly different and superior

  16. Passive Wireless SAW Humidity Sensors, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — This proposal describes the preliminary development of passive wireless surface acoustic wave (SAW) based humidity sensors for NASA application to distributed...

  17. Passive cavitation imaging with ultrasound arrays.

    Science.gov (United States)

    Salgaonkar, Vasant A; Datta, Saurabh; Holland, Christy K; Mast, T Douglas

    2009-12-01

    A method is presented for passive imaging of cavitational acoustic emissions using an ultrasound array, with potential application in real-time monitoring of ultrasound ablation. To create such images, microbubble emissions were passively sensed by an imaging array and dynamically focused at multiple depths. In this paper, an analytic expression for a passive image is obtained by solving the Rayleigh-Sommerfield integral, under the Fresnel approximation, and passive images were simulated. A 192-element array was used to create passive images, in real time, from 520-kHz ultrasound scattered by a 1-mm steel wire. Azimuthal positions of this target were accurately estimated from the passive images. Next, stable and inertial cavitation was passively imaged in saline solution sonicated at 520 kHz. Bubble clusters formed in the saline samples were consistently located on both passive images and B-scans. Passive images were also created using broadband emissions from bovine liver sonicated at 2.2 MHz. Agreement was found between the images and source beam shape, indicating an ability to map therapeutic ultrasound beams in situ. The relation between these broadband emissions, sonication amplitude, and exposure conditions are discussed.

  18. Hybrid Active-Passive Radiation Shielding System

    Data.gov (United States)

    National Aeronautics and Space Administration — A radiation shielding system is proposed that integrates active magnetic fields with passive shielding materials. The objective is to increase the shielding...

  19. Universality in passively advected hydrodynamic fields : the case of a passive vector with pressure

    NARCIS (Netherlands)

    Benzi, R.; Biferale, L.; Toschi, F.

    2001-01-01

    Universality of statistical properties of passive quantities advected by turbulent velocity fields at changing the passive forcing mechanism is discussed. In particular, we concentrate on the statistical properties of an hydrodynamic system with pressure. We present theoretical arguments and

  20. uPAR as anti-cancer target

    DEFF Research Database (Denmark)

    Lund, Ida K; Illemann, Martin; Thurison, Tine

    2011-01-01

    , and a potential diagnostic and predictive impact of the different uPAR forms has been reported. Hence, pericellular proteolysis seems to be a suitable target for anti-cancer therapy and numerous approaches have been pursued. Targeting of this process may be achieved by preventing the binding of uPA to u...... using mouse monoclonal antibodies (mAbs) against mouse uPA or uPAR. These reagents will target uPA and uPAR in both stromal cells and cancer cells, and their therapeutic potential can now be assessed in syngenic mouse cancer models....

  1. Limnological database for Par Pond: 1959 to 1980

    International Nuclear Information System (INIS)

    Tilly, L.J.

    1981-03-01

    A limnological database for Par Pond, a cooling reservoir for hot reactor effluent water at the Savannah River Plant, is described. The data are derived from a combination of research and monitoring efforts on Par Pond since 1959. The approximately 24,000-byte database provides water quality, primary productivity, and flow data from a number of different stations, depths, and times during the 22-year history of the Par Pond impoundment. The data have been organized to permit an interpretation of the effects of twenty years of cooling system operations on the structure and function of an aquatic ecosystem

  2. Protease-activated receptor (PAR2, but not PAR1, is involved in collateral formation and anti-inflammatory monocyte polarization in a mouse hind limb ischemia model.

    Directory of Open Access Journals (Sweden)

    Lisa G van den Hengel

    Full Text Available AIMS: In collateral development (i.e. arteriogenesis, mononuclear cells are important and exist as a heterogeneous population consisting of pro-inflammatory and anti-inflammatory/repair-associated cells. Protease-activated receptor (PAR1 and PAR2 are G-protein-coupled receptors that are both expressed by mononuclear cells and are involved in pro-inflammatory reactions, while PAR2 also plays a role in repair-associated responses. Here, we investigated the physiological role of PAR1 and PAR2 in arteriogenesis in a murine hind limb ischemia model. METHODS AND RESULTS: PAR1-deficient (PAR1-/-, PAR2-deficient (PAR2-/- and wild-type (WT mice underwent femoral artery ligation. Laser Doppler measurements revealed reduced post-ischemic blood flow recovery in PAR2-/- hind limbs when compared to WT, while PAR1-/- mice were not affected. Upon ischemia, reduced numbers of smooth muscle actin (SMA-positive collaterals and CD31-positive capillaries were found in PAR2-/- mice when compared to WT mice, whereas these parameters in PAR1-/- mice did not differ from WT mice. The pool of circulating repair-associated (Ly6C-low monocytes and the number of repair-associated (CD206-positive macrophages surrounding collaterals in the hind limbs were increased in WT and PAR1-/- mice, but unaffected in PAR2-/- mice. The number of repair-associated macrophages in PAR2-/- hind limbs correlated with CD11b- and CD115-expression on the circulating monocytes in these animals, suggesting that monocyte extravasation and M-CSF-dependent differentiation into repair-associated cells are hampered. CONCLUSION: PAR2, but not PAR1, is involved in arteriogenesis and promotes the repair-associated response in ischemic tissues. Therefore, PAR2 potentially forms a new pro-arteriogenic target in coronary artery disease (CAD patients.

  3. Novel role for proteinase-activated receptor 2 (PAR2) in membrane trafficking of proteinase-activated receptor 4 (PAR4).

    Science.gov (United States)

    Cunningham, Margaret R; McIntosh, Kathryn A; Pediani, John D; Robben, Joris; Cooke, Alexandra E; Nilsson, Mary; Gould, Gwyn W; Mundell, Stuart; Milligan, Graeme; Plevin, Robin

    2012-05-11

    Proteinase-activated receptors 4 (PAR(4)) is a class A G protein-coupled receptor (GPCR) recognized through the ability of serine proteases such as thrombin and trypsin to mediate receptor activation. Due to the irreversible nature of activation, a fresh supply of receptor is required to be mobilized to the cell surface for responsiveness to agonist to be sustained. Unlike other PAR subtypes, the mechanisms regulating receptor trafficking of PAR(4) remain unknown. Here, we report novel features of the intracellular trafficking of PAR(4) to the plasma membrane. PAR(4) was poorly expressed at the plasma membrane and largely retained in the endoplasmic reticulum (ER) in a complex with the COPI protein subunit β-COP1. Analysis of the PAR(4) protein sequence identified an arginine-based (RXR) ER retention sequence located within intracellular loop-2 (R(183)AR → A(183)AA), mutation of which allowed efficient membrane delivery of PAR(4). Interestingly, co-expression with PAR(2) facilitated plasma membrane delivery of PAR(4), an effect produced through disruption of β-COP1 binding and facilitation of interaction with the chaperone protein 14-3-3ζ. Intermolecular FRET studies confirmed heterodimerization between PAR(2) and PAR(4). PAR(2) also enhanced glycosylation of PAR(4) and activation of PAR(4) signaling. Our results identify a novel regulatory role for PAR(2) in the anterograde traffic of PAR(4). PAR(2) was shown to both facilitate and abrogate protein interactions with PAR(4), impacting upon receptor localization and cell signal transduction. This work is likely to impact markedly upon the understanding of the receptor pharmacology of PAR(4) in normal physiology and disease.

  4. Hydrogenation of GaAs covered by GaAlAs and subgrain boundary passivation

    Science.gov (United States)

    Djemel, A.; Castaing, J.; Chevallier, J.; Henoc, P.

    1992-12-01

    Cathodoluminescence (CL) has been performed to study the influence of hydrogen on electronic properties of GaAs with and without a GaAlAs layer. Recombination at sub-boundaries has been examined. These extended defects have been introduced by high temperature plastic deformation. The results show that they are passivated by hydrogen. The penetration of hydrogen is slowed down by the GaAlAs layer. La cathodoluminescence (CL) a été utilisée pour étudier l'influence de l'hydrogène sur les propriétés électroniques de GaAs nu et recouvert d'une couche de GaAlAs. Le caractère recombinant des sous-joints de grains a été examiné. Ces défauts étendus ont été introduits par déformation plastique à chaud. Les résultats montrent que l'hydrogène passive ces défauts. La pénétration de l'hydrogène à l'intérieur de GaAs est retardée par la présence de la couche de GaAlAs.

  5. Health risks of passive smoking.

    Science.gov (United States)

    Papier, C M; Stellman, S D

    1986-01-01

    Passive or involuntary smoking is the inhalation of smoke which escapes directly into the air from the lit end of a burning cigarette. This unfiltered smoke contains the same toxic components of the mainstream smoke inhaled directly by the smoker, including numerous carcinogens, many in greater concentrations. It has long been known that exposure to this type of smoke leads to increased respiratory and other adverse health conditions in non-smokers, especially children. During the past five years, evidence has been accumulating that risk of lung cancer is also higher, particularly in non-smoking women whose husbands smoke. Despite uncertainties and differences in interpretation of various cancer studies, there is ample justification for public health measures now in place or proposed, such as restriction or elimination of smoking in the workplace and in public places.

  6. Integrated Passive And Wireless Sensor

    KAUST Repository

    Li, Bodong

    2015-04-30

    A passive and wireless sensor is provided for sensing at least one of magnetic field, temperature or humidity. The sensor can provide only one of the sensing functions, individually or any combination of them simultaneously. It can be used for various applications where magnetic field changes, temperature and/or humidity need to be measured. In one or more embodiments, a surface acoustic wave (SAW) sensor is provided that can measure one or more of a magnetic field (or current that generates the magnetic field), temperature and humidity. In one or more embodiments, a magnetoimpedence (MI) sensor (for example a thin film giant magnetoimpedance (GMI) sensor), a thermally sensitive (for example a Lithium Niobite (LiNbO.sub.3)) substrate, and a humidity sensitive film (for example a hydrogel film) can be used as sensing elements.

  7. Integrated Passive And Wireless Sensor

    KAUST Repository

    Li, Bodong; Kosel, Jü rgen

    2015-01-01

    A passive and wireless sensor is provided for sensing at least one of magnetic field, temperature or humidity. The sensor can provide only one of the sensing functions, individually or any combination of them simultaneously. It can be used for various applications where magnetic field changes, temperature and/or humidity need to be measured. In one or more embodiments, a surface acoustic wave (SAW) sensor is provided that can measure one or more of a magnetic field (or current that generates the magnetic field), temperature and humidity. In one or more embodiments, a magnetoimpedence (MI) sensor (for example a thin film giant magnetoimpedance (GMI) sensor), a thermally sensitive (for example a Lithium Niobite (LiNbO.sub.3)) substrate, and a humidity sensitive film (for example a hydrogel film) can be used as sensing elements.

  8. Modelling of a passive autocatalytic hydrogen recombiner – a parametric study

    Directory of Open Access Journals (Sweden)

    Rożeń Antoni

    2015-03-01

    Full Text Available Operation of a passive autocatalytic hydrogen recombiner (PAR has been investigated by means of computational fluid dynamics methods (CFD. The recombiner is a self-active and self-adaptive device used to remove hydrogen from safety containments of light water nuclear reactors (LWR by means of a highly exothermic reaction with oxygen at the surface of a platinum or palladium catalyst. Different turbulence models (k-ω, k-ɛ, intermittency, RSM were applied in numerical simulations of: gas flow, heat and mass transport and chemical surface reactions occurring in PAR. Turbulence was found to improve mixing and mass transfer and increase hydrogen recombination rate for high gas flow rates. At low gas flow rates, simulation results converged to those obtained for the limiting case of laminar flow. The large eddy simulation technique (LES was used to select the best RANS (Reynolds average stress model. Comparison of simulation results obtained for two- and three-dimensional computational grids showed that heat and mass transfer occurring in PAR were virtually two-dimensional processes. The effect of hydrogen thermal diffusion was also discussed in the context of possible hydrogen ignition inside the recombiner.

  9. First-in-human uPAR PET

    DEFF Research Database (Denmark)

    Persson, Morten; Skovgaard, Dorthe; Brandt-Larsen, Malene

    2015-01-01

    A first-in-human clinical trial with Positron Emission Tomography (PET) imaging of the urokinase-type plasminogen activator receptor (uPAR) in patients with breast, prostate and bladder cancer, is described. uPAR is expressed in many types of human cancers and the expression is predictive...... for targeted molecular imaging with PET. The safety, pharmacokinetic, biodistribution profile and radiation dosimetry after a single intravenous dose of (64)Cu-DOTA-AE105 were assessed by serial PET and computed tomography (CT) in 4 prostate, 3 breast and 3 bladder cancer patients. Safety assessment...... of invasion, metastasis and indicates poor prognosis. uPAR PET imaging therefore holds promise to be a new and innovative method for improved cancer diagnosis, staging and individual risk stratification. The uPAR specific peptide AE105 was conjugated to the macrocyclic chelator DOTA and labeled with (64)Cu...

  10. Peptide-Based Optical uPAR Imaging for Surgery

    DEFF Research Database (Denmark)

    Juhl, Karina; Christensen, Anders; Persson, Morten

    2016-01-01

    Near infrared intra-operative optical imaging is an emerging technique with clear implications for improved cancer surgery by enabling a more distinct delineation of the tumor margins during resection. This modality has the potential to increase the number of patients having a curative radical...... tumor resection. In the present study, a new uPAR-targeted fluorescent probe was developed and the in vivo applicability was evaluated in a human xenograft mouse model. Most human carcinomas express high level of uPAR in the tumor-stromal interface of invasive lesions and uPAR is therefore considered...... an ideal target for intra-operative imaging. Conjugation of the flourophor indocyanine green (ICG) to the uPAR agonist (AE105) provides an optical imaging ligand with sufficiently high receptor affinity to allow for a specific receptor targeting in vivo. For in vivo testing, human glioblastoma xenograft...

  11. Contribution de la tomographie par coherence optique au diagnostic ...

    African Journals Online (AJOL)

    Contribution de la tomographie par coherence optique au diagnostic de la neuropathie optique toxique. C.O.A. Abouki, S Alamou, C.R.A. Assavedo, L Odoulami-Yehouessi, I Sounouvou, S Hounnou-Tchabi ...

  12. Passive and active protection of cotton textiles

    NARCIS (Netherlands)

    Bochove, C. van

    1967-01-01

    In rotproofing of cotton a distinction is made between passive and active protection. In passive protection, the structure of the cotton fibre is modified in such a way that the fibre can longer be attacked. This modification of structure can be effected on different levels: microscopical,

  13. Influence of passivation process on chip performance

    NARCIS (Netherlands)

    Lu, J.; Kovalgin, Alexeij Y.; Schmitz, Jurriaan

    2009-01-01

    In this work, we have studied the performance of CMOS chips before and after a low temperature post-processing step. In order to prevent damage to the IC chips by the post-processing steps, a first passivation layers is needed on top of the IC chips. Two different passivation layer deposition

  14. Passive and Portable Polymer Optical Fiber Cleaver

    DEFF Research Database (Denmark)

    Saez-Rodriguez, D.; Min, R.; Ortega, B.

    2016-01-01

    opening up the possibility of an electrically passive cleaver. In this letter, we describe the implementation and testing of a high quality cleaver based on a mechanical system formed by a constant force spring and a damper, which leads to the first reported electrical passive and portable cleaver....

  15. Passive house networks : How can they deliver?

    NARCIS (Netherlands)

    Mlecnik, E.

    2009-01-01

    This paper examines experiences with the diffusion of the passive house concept, applied to the situation of ‘emerging’ countries like Belgium and the Netherlands. Adopter categories considering the passive house concept are defined. A marketing study based on Rogers’ theory of diffusion of

  16. Passive Solar Construction--Design and Performance.

    Science.gov (United States)

    Conservation and Renewable Energy Inquiry and Referral Service (DOE), Silver Spring, MD.

    Presented is a list of books and reports intended to serve as technical sources of information for the building professional interested in energy conservation. These publications are grouped under these headings: (1) energy-conserving building design; (2) passive systems/design; (3) passive systems/performance; and (4) proceedings (of the American…

  17. Analysis of ParB-centromere interactions by multiplex SPR imaging reveals specific patterns for binding ParB in six centromeres of Burkholderiales chromosomes and plasmids.

    Directory of Open Access Journals (Sweden)

    Flavien Pillet

    Full Text Available Bacterial centromeres-also called parS, are cis-acting DNA sequences which, together with the proteins ParA and ParB, are involved in the segregation of chromosomes and plasmids. The specific binding of ParB to parS nucleates the assembly of a large ParB/DNA complex from which ParA-the motor protein, segregates the sister replicons. Closely related families of partition systems, called Bsr, were identified on the chromosomes and large plasmids of the multi-chromosomal bacterium Burkholderia cenocepacia and other species from the order Burkholeriales. The centromeres of the Bsr partition families are 16 bp palindromes, displaying similar base compositions, notably a central CG dinucleotide. Despite centromeres bind the cognate ParB with a narrow specificity, weak ParB-parS non cognate interactions were nevertheless detected between few Bsr partition systems of replicons not belonging to the same genome. These observations suggested that Bsr partition systems could have a common ancestry but that evolution mostly erased the possibilities of cross-reactions between them, in particular to prevent replicon incompatibility. To detect novel similarities between Bsr partition systems, we have analyzed the binding of six Bsr parS sequences and a wide collection of modified derivatives, to their cognate ParB. The study was carried out by Surface Plasmon Resonance imaging (SPRi mulitplex analysis enabling a systematic survey of each nucleotide position within the centromere. We found that in each parS some positions could be changed while maintaining binding to ParB. Each centromere displays its own pattern of changes, but some positions are shared more or less widely. In addition from these changes we could speculate evolutionary links between these centromeres.

  18. Analysis of ParB-centromere interactions by multiplex SPR imaging reveals specific patterns for binding ParB in six centromeres of Burkholderiales chromosomes and plasmids.

    Science.gov (United States)

    Pillet, Flavien; Passot, Fanny Marie; Pasta, Franck; Anton Leberre, Véronique; Bouet, Jean-Yves

    2017-01-01

    Bacterial centromeres-also called parS, are cis-acting DNA sequences which, together with the proteins ParA and ParB, are involved in the segregation of chromosomes and plasmids. The specific binding of ParB to parS nucleates the assembly of a large ParB/DNA complex from which ParA-the motor protein, segregates the sister replicons. Closely related families of partition systems, called Bsr, were identified on the chromosomes and large plasmids of the multi-chromosomal bacterium Burkholderia cenocepacia and other species from the order Burkholeriales. The centromeres of the Bsr partition families are 16 bp palindromes, displaying similar base compositions, notably a central CG dinucleotide. Despite centromeres bind the cognate ParB with a narrow specificity, weak ParB-parS non cognate interactions were nevertheless detected between few Bsr partition systems of replicons not belonging to the same genome. These observations suggested that Bsr partition systems could have a common ancestry but that evolution mostly erased the possibilities of cross-reactions between them, in particular to prevent replicon incompatibility. To detect novel similarities between Bsr partition systems, we have analyzed the binding of six Bsr parS sequences and a wide collection of modified derivatives, to their cognate ParB. The study was carried out by Surface Plasmon Resonance imaging (SPRi) mulitplex analysis enabling a systematic survey of each nucleotide position within the centromere. We found that in each parS some positions could be changed while maintaining binding to ParB. Each centromere displays its own pattern of changes, but some positions are shared more or less widely. In addition from these changes we could speculate evolutionary links between these centromeres.

  19. Prise en charge des intoxications par envenimation chez les enfants ...

    African Journals Online (AJOL)

    Les signes cliniques étaient dominés par les douleurs (98%) suivies des hémorragies (73,80%) pour les morsures de serpent, la douleur pour les piqures de scorpion (100%) et les oedèmes pour les piqures d'abeilles (100%). Les cas de morsure de serpent ont été traités par le sérum antivenimeux polyvalent. Conclusion: ...

  20. Intoxication par la paraphényléne-diamine

    African Journals Online (AJOL)

    raoul

    9 mars 2011 ... remède contre la douleur par Averbukh [8], ou contre la constipation par Schemesh [9], mais l´utilisation à des fins autolytique reste toujours prédominante. Le tableau clinique de l´intoxication à ... une anurie ayant nécessité le recours à l´hémodialyse. Ce taux de survenue d´IRA anurique est relativement ...

  1. Croissance epitaxiale de GaAs sur substrats de Ge par epitaxie par faisceaux chimiques

    Science.gov (United States)

    Belanger, Simon

    La situation energetique et les enjeux environnementaux auxquels la societe est confrontee entrainent un interet grandissant pour la production d'electricite a partir de l'energie solaire. Parmi les technologies actuellement disponibles, la filiere du photovoltaique a concentrateur solaire (CPV pour concentrator photovoltaics) possede un rendement superieur et mi potentiel interessant a condition que ses couts de production soient competitifs. La methode d'epitaxie par faisceaux chimiques (CBE pour chemical beam epitaxy) possede plusieurs caracteristiques qui la rendent interessante pour la production a grande echelle de cellules photovoltaiques a jonctions multiples a base de semi-conducteurs III-V. Ce type de cellule possede la meilleure efficacite atteinte a ce jour et est utilise sur les satellites et les systemes photovoltaiques a concentrateur solaire (CPV) les plus efficaces. Une des principales forces de la technique CBE se trouve dans son potentiel d'efficacite d'utilisation des materiaux source qui est superieur a celui de la technique d'epitaxie qui est couramment utilisee pour la production a grande echelle de ces cellules. Ce memoire de maitrise presente les travaux effectues dans le but d'evaluer le potentiel de la technique CBE pour realiser la croissance de couches de GaAs sur des substrats de Ge. Cette croissance constitue la premiere etape de fabrication de nombreux modeles de cellules solaires a haute performance decrites plus haut. La realisation de ce projet a necessite le developpement d'un procede de preparation de surface pour les substrats de germanium, la realisation de nombreuses sceances de croissance epitaxiale et la caracterisation des materiaux obtenus par microscopie optique, microscopie a force atomique (AFM), diffraction des rayons-X a haute resolution (HRXRD), microscopie electronique a transmission (TEM), photoluminescence a basse temperature (LTPL) et spectrometrie de masse des ions secondaires (SIMS). Les experiences ont permis

  2. Population Games, Stable Games, and Passivity

    Directory of Open Access Journals (Sweden)

    Michael J. Fox

    2013-10-01

    Full Text Available The class of “stable games”, introduced by Hofbauer and Sandholm in 2009, has the attractive property of admitting global convergence to equilibria under many evolutionary dynamics. We show that stable games can be identified as a special case of the feedback-system-theoretic notion of a “passive” dynamical system. Motivated by this observation, we develop a notion of passivity for evolutionary dynamics that complements the definition of the class of stable games. Since interconnections of passive dynamical systems exhibit stable behavior, we can make conclusions about passive evolutionary dynamics coupled with stable games. We show how established evolutionary dynamics qualify as passive dynamical systems. Moreover, we exploit the flexibility of the definition of passive dynamical systems to analyze generalizations of stable games and evolutionary dynamics that include forecasting heuristics as well as certain games with memory.

  3. Considerations on nuclear reactor passive safety systems

    International Nuclear Information System (INIS)

    2016-01-01

    After having indicated some passive safety systems present in electronuclear reactors (control bars, safety injection system accumulators, reactor cooling after stoppage, hydrogen recombination systems), this report recalls the main characteristics of passive safety systems, and discusses the main issues associated with the assessment of new passive systems (notably to face a sustained loss of electric supply systems or of cold water source) and research axis to be developed in this respect. More precisely, the report comments the classification of safety passive systems as it is proposed by the IAEA, outlines and comments specific aspects of these systems regarding their operation and performance. The next part discusses the safety approach, the control of performance of safety passive systems, issues related to their reliability, and the expected contribution of R and D (for example: understanding of physical phenomena which have an influence of these systems, capacities of simulation of these phenomena, needs of experimentations to validate simulation codes)

  4. Passive systems for light water reactors

    International Nuclear Information System (INIS)

    Adinolfi, R.; Noviello, L.

    1990-01-01

    The paper reviews the most original concepts that have been considered in Italy for the back-fitting of the nuclear power plants in order to reduce the probability and the importance of the release to the environment in case of a core melt. With reference either to BWR or PWR, passive concepts have been considered for back-fitting in the following areas: pump seals damage prevention and ECCS passive operation; reactor passive depressurization; molten reactor core passive cooling; metal containment passive water cooling through a water tank located at high level; containment isolation improvement through a sealing system; containment leaks control and limitation of environmental release. In addition some considerations will be made on the protection against external events introduced from the beginning on the PUN design either on building and equipment lay-out either on structure design. (author). 5 figs

  5. Passivity-based design of robust passive damping for LCL-filtered voltage source converters

    DEFF Research Database (Denmark)

    Wang, Xiongfei; Blaabjerg, Frede; Loh, Poh Chiang

    2015-01-01

    Passive damping is proven as a robust stabilizing technique for LCL-filtered voltage source converters. However, conventional design methods of passive dampers are based on the passive components only, while the inherent damping effect of time delay in the digital control system is overlooked....... In this paper, a frequency-domain passivity-based design approach is proposed, where the passive dampers are designed to eliminate the negative real part of the converter output admittance with closed-loop current control, rather than shaping the LCL-filter itself. Thus, the influence of time delay...... in the current control is included, which allows a relaxed design of the passive damper with the reduced power loss and improved stability robustness against grid parameters variations. Design procedures of two commonly used passive dampers with LCL-filtered VSCs are illustrated. Experimental results validate...

  6. Krsko NPP Quality Assurance Plan Application to Nuclear Safety Upgrade Projects (PCFV System and PAR System)

    International Nuclear Information System (INIS)

    Biscan, Romeo; Fifnja, Igor

    2014-01-01

    Nuklearna Elektrarna Krsko (NEK) has undertaken Nuclear Safety Upgrade Projects as a safety improvement driven by the lessons learned from the Fukushima-Daiichi Accident. Among other projects, new modification 1008-VA-L Passive Containment Filtered Vent (PCFV) System has been installed which acts as the last barrier minimizing the release of radioactive material into the environment in case of failure of all safety systems, and to insure containment integrity during beyond design basis accidents (BDBA). In addition, modification 1002-GH-L Severe Accident Hydrogen Control System (PAR) has been implemented to prevent and mitigate the consequences of explosive gas generation (hydrogen and carbon monoxide) in case of reactor core melting. To ensure containment integrity for all design basis accidents (DBA) and BDBA conditions, NEK has eliminated existing safety-related electrical recombiners, replaced them with two safety-related passive autocatalytic recombiners (PARs) and added 20 new PARs designed for the BDBA conditions. Krsko NPP Quality Assurance Plan has been applied to Nuclear Safety Upgrade Projects (PCFV System and PAR System) through the following activities: · Internal audit of modification process was performed. · Supplier audits were performed to evaluate QA program efficiency of the main design organization and engineering organizations. · Evaluation and approval of Suppliers were performed. · QA engineer was involved in the review and approval of 1008-VA-L and 1002-GH-L modification documentation (Conceptual Design Package, Design Modification Package, Installation Package, Field Design Change Request, Problem/Deficiency Report, and Final Documentation Package). · Purchasing documentation for modifications 1008-VA-L and 1002-GH-L (technical specifications, purchase orders) has been verified and approved by QA. · QA and QC engineers were involved in oversight of production and testing of the new 1008-VA-L and 1002-GH-L plant components.

  7. Serum suPAR in patients with FSGS: trash or treasure?

    NARCIS (Netherlands)

    Maas, R.J.H.; Deegens, J.K.J.; Wetzels, J.F.M.

    2013-01-01

    The urokinase-type plasminogen activator receptor (uPAR) has important functions in cell migration. uPAR can be shed from the cell membrane resulting in soluble uPAR (suPAR). Further cleavage gives rise to shorter fragments with largely unknown functions. Recent studies have demonstrated that both

  8. Une terreur par l’image

    Directory of Open Access Journals (Sweden)

    Annie DULONG

    2011-09-01

    Full Text Available Si d’autres événements — Hiroshima, la découverte des camps de concentration, la chute du mur de Berlin — ont, au cours du XXe siècle, marqué suffisamment l’imaginaire pour trouver leur réponse dans des œuvres d’art, le 11 septembre 2001 pose la question de la fictionnalisation autrement : il ne s’agit plus tant de combler les manques de la représentation, liés à l’absence d’images ou au délai dans leur dévoilement, mais bien de composer avec l’omniprésence d’une représentation martelée à la télévision et sur Internet. Que cette représentation soit partielle, tronquée et qu’il lui manque la présence des corps, ces grands absents des photographies et des images tournées par les journalistes, ne change rien au fait que c’est avec le trop-plein que les artistes doivent maintenant négocier.Cet article s’intéresse aux romans qui traitent l’événement de front au lieu de l’aborder sur un mode mineur, et a pour objectif de tracer un portrait de la représentation des médias dans les romans du 11 septembre 2001. Ces romans, outre le fait qu’ils traitent des événements de New York, ont comme point commun un personnage, ou décor : les médias, représentés par la télévision, l’Internet, les photographies de presse, interviennent dans les récits d’une manière significative et témoignent de la force brute des images. À travers une étude de certains des mécanismes à l’œuvre dans The Writing on the Wall (Lynne Sharon Schwartz, Extremely Loud and Incredibly Close (Jonathan Safran Foer, Falling Man (Don DeLillo et A Disorder Peculiar to the Country (Ken Kalfus, il s’agira de proposer des réponses à ces quelques questions : quel rôle les médias jouent-ils, et comment participent-ils au récit ? Quelle pression les images exercent-elles sur les personnages ? Que révèlent les personnages enfants dans leur rapport aux médias ? Quelle critique, finalement, les romans

  9. Citric Acid Passivation of Stainless Steel

    Science.gov (United States)

    Yasensky, David; Reali, John; Larson, Chris; Carl, Chad

    2009-01-01

    Passivation is a process for cleaning and providing corrosion protection for stainless steel. Currently, on Kennedy Space Center (KSC), only parts passivated with nitric acid are acceptable for use. KSC disposes of approximately 125gal of concentrated nitric acid per year, and receives many parts from vendors who must also dispose of used nitric acid. Unfortunately, nitric acid presents health and environmental hazards. As a result, several recent industry studies have examined citric acid as an alternative. Implementing a citric acid-based passivation procedure would improve the health and environmental safety aspects of passivation process. However although there is a lack of published studies that conclusively prove citric acid is a technically sound passivation agent. In 2007, NASA's KSC Materials Advisory Working Group requested the evaluation of citric acid in place of nitric acid for passivation of parts at KSC. United Space Alliance Materials & Processes engineers have developed a three-phase test plan to evaluate citric acid as an alternative to nitric acid on three stainless steels commonly used at KSC: UNS S30400, S41000, and S17400. Phases 1 and 2 will produce an optimized citric acid treatment based on results from atmospheric exposure at NASA's Beach Corrosion Facility. Phase 3 will compare the optimized solution(s) with nitric acid treatments. If the results indicate that citric acid passivates as well or better than nitric acid, NASA intends to approve this method for parts used at the Kennedy Space Center.

  10. Evaluating the Relationship between Equilibrium Passive ...

    Science.gov (United States)

    Objectives. This review evaluates passive sampler uptake of hydrophobic organic contaminants (HOCs) in water column and interstitial water exposures as a surrogate for organism bioaccumulation. Approach/Activities. Fifty-five studies were found where both passive sampler uptake and organism bioaccumulation were measured and 19 of these investigations provided direct comparisons relating passive sampler uptake and organism bioaccumulation. Polymers compared included low density polyethylene (LDPE), polyoxymethylene (POM), and polydimethylsiloxane (PDMS), and organisms ranged from polychaetes and oligochaetes to bivalves, aquatic insects, and gastropods. Regression equations correlating bioaccumulation (CL) and passive sampler uptake (CPS) were used to assess the strength of observed relationships. Results/Lessons Learned. Passive sampling based concentrations resulted in strong logarithmic regression relationships, most of which were within one to two orders of magnitude of measured bioaccumulation. Mean coefficients of determination (r2) for LDPE, PDMS and POM were 0.68, 0.76 and 0.58, respectively. For the available raw data, the mean ratio of CL and CPS was 10.8 ± 18.4 (n = 609). Passive sampler uptake and bioaccumulation were not found to be identical (i.e., CPS ≠ CL) but the logarithmic-based relationships between these values were consistently linear and predictive. This review concludes that in many applications passive sampling may serve as a

  11. Levantamento soro-epidemiológico da infecção pelo vírus da Anemia Infecciosa Eqüina, da Influenza Eqüina-2 e do Herpesvírus Eqüino-1 em rebanhos do sul do Estado do Pará, Brasil

    Directory of Open Access Journals (Sweden)

    Lindomar José Pena

    2006-08-01

    Full Text Available Equine infectious anemia virus (EIAV, equine influenza virus type 2 (EIV-2 and equine herpesvirus type 1 (EHV-1 are the causal agents of diseases that may bring economical losses. The aim of this present study was to estimate the frequency of antibodies against EIAV, EIV-2 and EHV-1 in herds of south Pará State, Brazil. Antibodies against EIAV, EIV-2 and EHV-1 were detected by AGID, hemagglutination inhibition method and serum neutralization technique (TCID50 =100, respectively. Blood samples of 572, 514, and 506 healthy equine unvaccinated against any of the three viruses were tested, respectively, for EIAV, EIV-2 and EHV-1. The following frequencies of serum reactors animals were observed: EIAV,1,34%; EIV-2, 35,79%; EHV-1, 45,45%. These results show that the agents are present in herds from Pará herds and the adoption of measures of management and prophylaxis should be prioritized, ensuring, thereby, the prosperity of brazilian's breeding equine.

  12. Par Pond vegetation status Summer 1995 -- June survey descriptive summary

    International Nuclear Information System (INIS)

    Mackey, H.E. Jr.; Riley, R.S.

    1995-06-01

    The water level of Par Pond was lowered approximately 20 feet in mid-1991 in order to protect downstream residents from possible dam failure suggested by subsidence on the downstream slope of the dam and to repair the dam. This lowering exposed both emergent and nonemergent macrophyte beds to drying conditions resulting in extensive losses. A survey of the shoreline aquatic plant communities in June 1995, three months after the refilling of Par Pond to approximately 200 feet above mean sea level, indicated that much of the original plant communities and the intermediate shoreline communities present on the exposed sediments have been lost. The extensive old-field and emergent marsh communities that were present on the exposed shoreline during the drawdown have been flooded and much of the pre-drawdown Par Pond aquatic plant communities have not had sufficient time for re-establishment. The shoreline does, however, have extensive beds of maidencane which extend from the shoreline margin to areas as deep as 2 and perhaps 3 meters. Scattered individual plants of lotus and watershield are common and may indicate likely directions of future wetland development in Par Pond. In addition, within isolated coves, which apparently received ground water seepage and/or stream surface flows during the period of the Par Pond draw down, extensive beds of waterlilies and spike rush are common. Invasion of willow and red maple occurred along the lake shoreline as well. Although not absent from this survey, evidence of the extensive redevelopment of the large cattail and eel grass beds was not observed in this first survey of Par Pond. Future surveys during the growing seasons of 1995, 1996, and 1997 along with the evaluation of satellite date to map the areal extent of the macrophyte beds of Par Pond are planned

  13. Passive detection of vehicle loading

    Science.gov (United States)

    McKay, Troy R.; Salvaggio, Carl; Faulring, Jason W.; Salvaggio, Philip S.; McKeown, Donald M.; Garrett, Alfred J.; Coleman, David H.; Koffman, Larry D.

    2012-01-01

    The Digital Imaging and Remote Sensing Laboratory (DIRS) at the Rochester Institute of Technology, along with the Savannah River National Laboratory is investigating passive methods to quantify vehicle loading. The research described in this paper investigates multiple vehicle indicators including brake temperature, tire temperature, engine temperature, acceleration and deceleration rates, engine acoustics, suspension response, tire deformation and vibrational response. Our investigation into these variables includes building and implementing a sensing system for data collection as well as multiple full-scale vehicle tests. The sensing system includes; infrared video cameras, triaxial accelerometers, microphones, video cameras and thermocouples. The full scale testing includes both a medium size dump truck and a tractor-trailer truck on closed courses with loads spanning the full range of the vehicle's capacity. Statistical analysis of the collected data is used to determine the effectiveness of each of the indicators for characterizing the weight of a vehicle. The final sensing system will monitor multiple load indicators and combine the results to achieve a more accurate measurement than any of the indicators could provide alone.

  14. Illegal Passive Smoking at Work

    Directory of Open Access Journals (Sweden)

    François-Xavier Lesage

    2011-01-01

    Results. Ninety-five percent of a total group of 172 OP of Champagne county filled the postal questionnaire. More than 80% of OP's replies identified illegal PSW. The average prevalence of PSW exposure was 0.7% of the total working population. Environmental tobacco smoke (ETS levels were considered between low and medium for most passive smokers (71%. Main features exposure to ETS at work for non-smokers was associated with female gender (69.5%, age between 40 and 49 years (41.2% and belonging to tertiary sector (75.6%. Environmental tobacco smoke exposures at work was firstly in the office for 49.7% of the subjects and secondly in the restroom for 18% of them. Main medical symptoms encountered by non-smokers were respiratory tractus irritation (81.7%. Eighty-three percent of OPs indicated solution to eradicate PSW. Illegal PSW is really weaker than fifteen years ago. However, the findings support a real ban on smoking in the workplace in order to protect all workers.

  15. [Passive euthanasia and living will].

    Science.gov (United States)

    Julesz, Máté

    2014-07-06

    This article deals with the intentional distinction between murder of first degree and passive euthanasia. In Hungary, active euthanasia is considered to be a murder of first degree, whilst the Netherlands, Belgium, Luxemburg and Switzerland have legalized the active form of mercy killing in Europe. The palliative terminal care, when e.g. giving pain-killer morphine to the patient, might result in decreasing the patient's life-span, and thus causing indirect euthanasia. However, the legal institution of living will exists in several counter-euthanasia countries. The living will allows future patients to express their decision in advance to refuse a life-sustaining treatment, e.g. in case of irreversible coma. The institution of living will exists in Germany and in Hungary too. Nevertheless, the formal criteria of living will make it hardly applicable. The patient ought to express his/her will before a notary public in advance, and he/she should hand it over when being hospitalized. If the patient is not able to present his/her living will to his/her doctor in the hospital, then his/her only hope remains that he/she has given a copy of the living will to the family doctor previously, and the family doctor will notify the hospital.

  16. PASSIVE DETECTION OF VEHICLE LOADING

    Energy Technology Data Exchange (ETDEWEB)

    Garrett, A.

    2012-01-03

    The Digital Imaging and Remote Sensing Laboratory (DIRS) at the Rochester Institute of Technology, along with the Savannah River National Laboratory is investigating passive methods to quantify vehicle loading. The research described in this paper investigates multiple vehicle indicators including brake temperature, tire temperature, engine temperature, acceleration and deceleration rates, engine acoustics, suspension response, tire deformation and vibrational response. Our investigation into these variables includes building and implementing a sensing system for data collection as well as multiple full-scale vehicle tests. The sensing system includes; infrared video cameras, triaxial accelerometers, microphones, video cameras and thermocouples. The full scale testing includes both a medium size dump truck and a tractor-trailer truck on closed courses with loads spanning the full range of the vehicle's capacity. Statistical analysis of the collected data is used to determine the effectiveness of each of the indicators for characterizing the weight of a vehicle. The final sensing system will monitor multiple load indicators and combine the results to achieve a more accurate measurement than any of the indicators could provide alone.

  17. Passive fault current limiting device

    Science.gov (United States)

    Evans, Daniel J.; Cha, Yung S.

    1999-01-01

    A passive current limiting device and isolator is particularly adapted for use at high power levels for limiting excessive currents in a circuit in a fault condition such as an electrical short. The current limiting device comprises a magnetic core wound with two magnetically opposed, parallel connected coils of copper, a high temperature superconductor or other electrically conducting material, and a fault element connected in series with one of the coils. Under normal operating conditions, the magnetic flux density produced by the two coils cancel each other. Under a fault condition, the fault element is triggered to cause an imbalance in the magnetic flux density between the two coils which results in an increase in the impedance in the coils. While the fault element may be a separate current limiter, switch, fuse, bimetal strip or the like, it preferably is a superconductor current limiter conducting one-half of the current load compared to the same limiter wired to carry the total current of the circuit. The major voltage during a fault condition is in the coils wound on the common core in a preferred embodiment.

  18. Passive Cooling of Body Armor

    Science.gov (United States)

    Holtz, Ronald; Matic, Peter; Mott, David

    2013-03-01

    Warfighter performance can be adversely affected by heat load and weight of equipment. Current tactical vest designs are good insulators and lack ventilation, thus do not provide effective management of metabolic heat generated. NRL has undertaken a systematic study of tactical vest thermal management, leading to physics-based strategies that provide improved cooling without undesirable consequences such as added weight, added electrical power requirements, or compromised protection. The approach is based on evaporative cooling of sweat produced by the wearer of the vest, in an air flow provided by ambient wind or ambulatory motion of the wearer. Using an approach including thermodynamic analysis, computational fluid dynamics modeling, air flow measurements of model ventilated vest architectures, and studies of the influence of fabric aerodynamic drag characteristics, materials and geometry were identified that optimize passive cooling of tactical vests. Specific architectural features of the vest design allow for optimal ventilation patterns, and selection of fabrics for vest construction optimize evaporation rates while reducing air flow resistance. Cooling rates consistent with the theoretical and modeling predictions were verified experimentally for 3D mockups.

  19. Passivation Effects in Copper Thin Films

    International Nuclear Information System (INIS)

    Wiederhirn, G.; Nucci, J.; Richter, G.; Arzt, E.; Balk, T. J.; Dehm, G.

    2006-01-01

    We studied the influence of a 10 nm AlxOy passivation on the stress-temperature behavior of 100 nm and 1 μm thick Cu films. At low temperatures, the passivation induces a large tensile stress increase in the 100 nm film; however, its effect on the 1 μm film is negligible. At high temperatures, the opposite behavior is observed; while the passivation does not change the 100 nm film behavior, it strengthens the 1 μm film by driving it deeper into compression. These observations are explained in light of a combination of constrained diffusional creep and dislocation dynamics unique to ultra-thin films

  20. Python passive network mapping P2NMAP

    CERN Document Server

    Hosmer, Chet

    2015-01-01

    Python Passive Network Mapping: P2NMAP is the first book to reveal a revolutionary and open source method for exposing nefarious network activity. The ""Heartbleed"" vulnerability has revealed significant weaknesses within enterprise environments related to the lack of a definitive mapping of network assets. In Python Passive Network Mapping, Chet Hosmer shows you how to effectively and definitively passively map networks. Active or probing methods to network mapping have traditionally been used, but they have many drawbacks - they can disrupt operations, crash systems, and - most important

  1. Non-Chromate Passivation of Zinc

    DEFF Research Database (Denmark)

    Tang, Peter Torben; Bech-Nielsen, G.

    1993-01-01

    Phos). The treatments are within the same concentration region, and they have a mutual pat-ent pending. Although some tests still need to be conducted, the following aspects are clear at the present time: The general appearance of the passivated zinc surface is very similar to a standard yellow chromate treatment...... successfully. The corrosion resistance against white rust on zinc and zinc alloys is just as good as that of yellow chromate, although the result de-pends on the corrosion test method as well as on the nature of the zinc substrate pas-sivated. The passivation procedure is simply a dip for approxi-mately 2...

  2. Par Pond vegetation status Summer 1995 -- September survey descriptive summary

    International Nuclear Information System (INIS)

    Mackey, H.E. Jr.; Riley, R.S.

    1995-09-01

    The water level of Par Pond was lowered approximately 20 feet in mid-1991 in order to protect downstream residents from possible dam failure suggested by subsidence on the downstream slope of the dam and to repair the dam. This lowering exposed both emergent and nonemergent macrophyte beds to drying conditions resulting in extensive losses. A survey of the emergent shoreline aquatic plant communities began in June 1995, three months after the refilling of Par Pond to approximately 200 feet above mean sea level and continued with this mid-September survey. Communities similar to the pre-drawdown Par Pond aquatic plant communities are becoming re-established; especially, beds of maidencane, lotus, waterlily, and watershield are now extensive and well established. Cattail occurrence continues to increase, but large beds common to Par Pond prior to the drawdown have not formed. Future surveys during the late growing seasons of 1995, and throughout 1996 and 1997, along with the evaluation of satellite data to map the areal extent of the macrophyte beds of Par Pond, are planned

  3. Par Pond vegetation status Summer 1995 -- October survey descriptive summary

    International Nuclear Information System (INIS)

    Mackey, H.E. Jr.; Riley, R.S.

    1995-11-01

    The water level of Par Pond was lowered approximately 20 feet in mid-1991 in order to protect downstream residents from possible dam failure suggested by subsidence on the downstream slope of the dam and to repair the dam. This lowering exposed both emergent and nonemergent macrophyte beds to drying conditions resulting in extensive losses. A survey of the emergent shoreline aquatic plant communities began in June 1995, three months after the refilling of Par Pond to approximately 200 feet above mean sea level and continued with this late October survey. Communities similar to the pre-drawdown Par Pond aquatic plant communities are becoming re-established; especially, beds of maiden cane, lotus, waterlily, and watershield are now extensive and well established. Cattail occurrence continues to increase, but large beds common to Par Pond prior to the drawdown have not formed. Future surveys throughout 1996 and 1997, along with the continued evaluation of satellite data to map the areal extent of the macrophyte beds of Par Pond, are planned

  4. Lipid-Based Passivation in Nanofluidics

    Science.gov (United States)

    2012-01-01

    Stretching DNA in nanochannels is a useful tool for direct, visual studies of genomic DNA at the single molecule level. To facilitate the study of the interaction of linear DNA with proteins in nanochannels, we have implemented a highly effective passivation scheme based on lipid bilayers. We demonstrate virtually complete long-term passivation of nanochannel surfaces to a range of relevant reagents, including streptavidin-coated quantum dots, RecA proteins, and RecA–DNA complexes. We show that the performance of the lipid bilayer is significantly better than that of standard bovine serum albumin-based passivation. Finally, we show how the passivated devices allow us to monitor single DNA cleavage events during enzymatic degradation by DNase I. We expect that our approach will open up for detailed, systematic studies of a wide range of protein–DNA interactions with high spatial and temporal resolution. PMID:22432814

  5. Hydrodynamic interaction between bacteria and passive sphere

    Science.gov (United States)

    Zhang, Bokai; Ding, Yang; Xu, Xinliang

    2017-11-01

    Understanding hydrodynamic interaction between bacteria and passive sphere is important for identifying rheological properties of bacterial and colloidal suspension. Over the past few years, scientists mainly focused on bacterial influences on tracer particle diffusion or hydrodynamic capture of a bacteria around stationary boundary. Here, we use superposition of singularities and regularized method to study changes in bacterial swimming velocity and passive sphere diffusion, simultaneously. On this basis, we present a simple two-bead model that gives a unified interpretation of passive sphere diffusion and bacterial swimming. The model attributes both variation of passive sphere diffusion and changes of speed of bacteria to an effective mobility. Using the effective mobility of bacterial head and tail as an input function, the calculations are consistent with simulation results at a broad range of tracer diameters, incident angles and bacterial shapes.

  6. Decision Support on Small size Passive Samples

    Directory of Open Access Journals (Sweden)

    Vladimir Popukaylo

    2018-05-01

    Full Text Available A construction technique of adequate mathematical models for small size passive samples, in conditions when classical probabilistic-statis\\-tical methods do not allow obtaining valid conclusions was developed.

  7. Experiments, Passive Observation and Scenario Analysis

    DEFF Research Database (Denmark)

    Hoover, Kevin D.; Juselius, Katarina

    The paper provides a careful, analytical account of Trygve Haavelmo's unsystematic, but important, use of the analogy between controlled experiments common in the natural sciences and econometric techniques. The experimental analogy forms the linchpin of the methodology for passive observation...

  8. Thermophysiological adaptations to passive mild heat acclimation

    NARCIS (Netherlands)

    Pallubinsky, H; Schellen, L; Kingma, B R M; Dautzenberg, B; van Baak, M A; van Marken Lichtenbelt, W D

    Passive mild heat acclimation (PMHA) reflects realistic temperature challenges encountered in everyday life. Active heat acclimation, combining heat exposure and exercise, influences several important thermophysiological parameters; for example, it decreases core temperature and enhances heat

  9. Passive water and ion transport by cotransporters

    DEFF Research Database (Denmark)

    Loo, D D; Hirayama, B A; Meinild, A K

    1999-01-01

    the Lp of control oocytes. Passive Na+ transport (Na+ leak) was obtained from the blocker-sensitive Na+ currents in the absence of substrates (glucose and GABA). 2. Passive Na+ and water transport through SGLT1 were blocked by phlorizin with the same sensitivity (inhibitory constant (Ki), 3-5 micro......1. The rabbit Na+-glucose (SGLT1) and the human Na+-Cl--GABA (GAT1) cotransporters were expressed in Xenopus laevis oocytes, and passive Na+ and water transport were studied using electrical and optical techniques. Passive water permeabilities (Lp) of the cotransporters were determined from......M). When Na+ was replaced with Li+, phlorizin also inhibited Li+ and water transport, but with a lower affinity (Ki, 100 microM). When Na+ was replaced by choline, which is not transported, the SGLT1 Lp was indistinguishable from that in Na+ or Li+, but in this case water transport was less sensitive...

  10. Climate-Specific Passive Building Standards

    Energy Technology Data Exchange (ETDEWEB)

    Wright, Graham S. [Building Science Corp., Westford, MA (United States); Klingenberg, Katrin [Building Science Corp., Westford, MA (United States)

    2015-07-29

    In 2012, the U.S. Department of Energy (DOE) recognized the value of performance-based passive building standards when it joined with Passive House Institute US (PHIUS) to promote DOE’s Challenge Home program in tandem with the PHIUS+ Certification program. Since then, the number of passive building projects that have been certified under the partnership has grown exponentially because of some synergy. Passive building represents a well-developed approach to arrive at the envelope basis for zero energy and energy-positive projects by employing performance-based criteria and maximizing cost-effective savings from conservation before implementing renewable energy technologies. The Challenge Home program evolved into the Zero Energy Ready Home (ZERH) program in a move toward 1) attaining zero energy and 2) including active renewable energy generation such as photovoltaics (PV)—toward the zero energy goal.

  11. Symmetry Breaking in a random passive scalar

    Science.gov (United States)

    Kilic, Zeliha; McLaughlin, Richard; Camassa, Roberto

    2017-11-01

    We consider the evolution of a decaying passive scalar in the presence of a gaussian white noise fluctuating shear flow. We focus on deterministic initial data and establish the short, intermediate, and long time symmetry properties of the evolving point wise probability measure for the random passive scalar. Analytical results are compared directly to Monte Carlo simulations. Time permitting we will compare the predictions to experimental observations.

  12. Comprehensive Planning for Passive Solar Architectural Retrofit

    Science.gov (United States)

    1980-05-01

    technical information, and the natural environ- ment. Since the Air Force Energy plan stresses Passive Solar (Architecture) before using Active Solar...retrofitted by-1990, and the Air Force Energy Plan stresses Passive Solar Applications. Bdcause of this requirement, you must consider the following retrofit...OF THI SUN AT NOON ON O CUMIN 21 EXAWMKU[ AT 3M. AN I S - W Figure 12-4 12-3 Skylight- use a reflector ,with horizontal skylights to ,iincrease solar

  13. An All-Silicon Passive Optical Diode

    OpenAIRE

    Fan, Li; Wang, Jian; Varghese, Leo T.; Shen, Hao; Niu, Ben; Xuan, Yi; Weiner, Andrew M.; Qi, Minghao

    2011-01-01

    A passive optical diode effect would be useful for on-chip optical information processing but has been difficult to achieve. Using a method based on optical nonlinearity, we demonstrate a forward-backward transmission ratio of up to 28 decibels within telecommunication wavelengths. Our device, which uses two silicon rings 5 micrometers in radius, is passive yet maintains optical nonreciprocity for a broad range of input power levels, and it performs equally well even if the backward input pow...

  14. Technical - Economic Research for Passive Buildings

    Science.gov (United States)

    Miniotaite, Ruta

    2017-10-01

    A newly constructed passive house must save 80 % of heat resources; otherwise it is not a passive house. The heating energy demand of a passive building is less than 15 kWh/m2 per year. However, a passive house is something more than just an energy-saving house. This concept involves sustainable, high-quality, valuable, healthy and durable construction. Features of a passive house: high insulation of envelope components, high-quality windows, good tightness of the building, regenerative ventilation system and elimination of thermal bridges. The Energy Performance of Buildings Directive (EPBD) 61 requires all new public buildings to become near-zero energy buildings by 2019 and will be extended to all new buildings by 2021. This concept involves sustainable, high-quality, valuable, healthy and durable construction. Foundation, walls and roofs are the most essential elements of a house. The type of foundation for a private house is selected considering many factors. The article examines technological and structural solutions for passive buildings foundation, walls and roofs. The technical-economic comparison of the main structures of a passive house revealed that it is cheaper to install an adequately designed concrete slab foundation than to build strip or pile foundation and the floor separately. Timber stud walls are the cheapest wall option for a passive house and 45-51% cheaper compared to other options. The comparison of roofs and ceilings showed that insulation of the ceiling is 25% more efficient than insulation of the roof. The comparison of the main envelope elements efficiency by multiple-criteria evaluation methods showed that it is economically feasible to install concrete slab on ground foundation, stud walls with sheet cladding and a pitched roof with insulated ceiling.

  15. Active and passive cooling methods for dwellings

    DEFF Research Database (Denmark)

    Oropeza-Perez, Ivan; Østergaard, Poul Alberg

    2018-01-01

    In this document a review of three active as well as ten passive cooling methods suitable for residential buildings is carried out. The review firstly addresses how the various technologies cool the space according to the terms of the building heat balance, under what technical conditions...... ventilation, controlled ventilation, roof coating and eco-evaporative cooling are the most suitable passive methods for an extensive use in this country....

  16. New Frontiers in Passive and Active Nanoantennas

    DEFF Research Database (Denmark)

    Arslanagic, Samel; Ziolkowski, Richard W.

    2017-01-01

    The articles included in this special section focus on several recent advances in the field of passive and active nanoantennas that employ not only traditional based realizations but also their new frontiers.......The articles included in this special section focus on several recent advances in the field of passive and active nanoantennas that employ not only traditional based realizations but also their new frontiers....

  17. Uncertainty Prediction in Passive Target Motion Analysis

    Science.gov (United States)

    2016-05-12

    Number 15/152,696 Filing Date 12 May 2016 Inventor John G. Baylog et al Address any questions concerning this matter to the Office of...300118 1 of 25 UNCERTAINTY PREDICTION IN PASSIVE TARGET MOTION ANALYSIS STATEMENT OF GOVERNMENT INTEREST [0001] The invention described herein...at an unknown location and following an unknown course relative to an observer 12. Observer 12 has a sensor array such as a passive sonar or radar

  18. Feasibility of passive heat removal systems

    Energy Technology Data Exchange (ETDEWEB)

    Ashurko, Yu M [Institute of Physics and Power Engineering, Obninsk (Russian Federation)

    1996-12-01

    This paper presents a review of decay heat removal systems (DHRSs) used in liquid metal-cooled fast reactors (LMFRs). Advantages and the disadvantages of these DHRSs, extent of their passivity and prospects for their use in advanced fast reactor projects are analyzed. Methods of extending the limitations on the employment of individual systems, allowing enhancement in their effectiveness as safety systems and assuring their total passivity are described. (author). 10 refs, 10 figs.

  19. Architectural design of passive solar residential building

    Directory of Open Access Journals (Sweden)

    Ma Jing

    2015-01-01

    Full Text Available This paper studies thermal environment of closed balconies that commonly exist in residential buildings, and designs a passive solar residential building. The design optimizes the architectural details of the house and passive utilization of solar energy to provide auxiliary heating for house in winter and cooling in summer. This design might provide a more sufficient and reasonable modification for microclimate in the house.

  20. Brookfield Homes Passive House Performance Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Herk, A. [IBACOS, Inc., Pittsburgh, PA (United States); Poerschke, A. [IBACOS, Inc., Pittsburgh, PA (United States); Beach, R. [IBACOS, Inc., Pittsburgh, PA (United States)

    2016-02-01

    In 2012-2013, IBACOS worked with a builder, Brookfield Homes in Denver, Colorado, to design and construct a Passive House certified model home. IBACOS used several modeling programs and calculation methods to complete the final design package along with Brookfield's architect KGA Studio. This design package included upgrades to the thermal enclosure, basement insulation, windows, and heating, ventilation, and air conditioning. Short-term performance testing in the Passive House was done during construction and after construction.

  1. Isolation and Identification of Egg Drop Syndrome Virus with Hemagglutination and Hemagglutination Tests

    Directory of Open Access Journals (Sweden)

    Fidyah Fitrawati

    2015-11-01

    of 0,8. The HA test in uterine sample of both SR/WNO/2011 and FF/Sleman/2011 showed the titer 23 HA units and egg washed water sample of FF/Sleman/2011 showed titer 22 HA units. The HI test for comparison with ND and AI anti serum was negative, while the test with EDS anti serum showed positive results. Based on the HA and HI test results, it was concluded that the virus grown in the allantoic fluid is EDS virus.

  2. Passive Safety Features for Small Modular Reactors

    International Nuclear Information System (INIS)

    Ingersoll, Daniel T.

    2010-01-01

    The rapid growth in the size and complexity of commercial nuclear power plants in the 1970s spawned an interest in smaller, simpler designs that are inherently or intrinsically safe through the use of passive design features. Several designs were developed, but none were ever built, although some of their passive safety features were incorporated into large commercial plant designs that are being planned or built today. In recent years, several reactor vendors are actively redeveloping small modular reactor (SMR) designs with even greater use of passive features. Several designs incorporate the ultimate in passive safety they completely eliminate specific accident initiators from the design. Other design features help to reduce the likelihood of an accident or help to mitigate the accidents consequences, should one occur. While some passive safety features are common to most SMR designs, irrespective of the coolant technology, other features are specific to water, gas, or liquid-metal cooled SMR designs. The extensive use of passive safety features in SMRs promise to make these plants highly robust, protecting both the general public and the owner/investor. Once demonstrated, these plants should allow nuclear power to be used confidently for a broader range of customers and applications than will be possible with large plants alone.

  3. Active versus passive screening for entrance control

    International Nuclear Information System (INIS)

    McCormick, N.J.

    1976-01-01

    The benefits of different entrance control actions are quantitatively assessed by defining a relative improvement index for the screening activity. Three classes of entrance control measures are investigated: the use of a purely active screening measure (such as a portal monitor), the use of a purely passive screening measure (such as personality typing), and the combined use of active and passive measures. Active entrance control measures have been studied previously [McCormick and Erdmann, Nucl. Mat. Manag. 4, (1975)] where it was determined that the relative improvement index is approximately related to the nondetection probability factor r for the protective system by (1-r + r ln r). It is shown here that the relative improvement index for a purely passive screening system also can be approximately expressed in a convenient manner. Because the probability is very small that a sabotage or diversion action would be attempted, the result for passive screening, multiplied by r, may be combined with the factor (1-r + r ln r) to give the relative improvement index for a combined, active-and-passive entrance control system. Results from simple example calculations indicate that passive screening of nuclear plant personnel or applicants for such positions is orders-of-magnitude less effective than portal monitors or reasonable improvements in them. 5 tables

  4. [Ambroise Paré, his death and his historians].

    Science.gov (United States)

    Dumaître, P

    2001-01-01

    Ambroise Paré died December the 20th., 1590. What happened after his death and what are we knowing about his life? Never forgotten, though a lack of care, we were waiting till the XIXth. century to get recollection upon a subject sustained only by accounts of his travels. After Percy, a surgeon who tried to write Paré's biography through the "Biographie universelle ancienne et moderne, de Michaud (1822)" and some second rank authors, Malgaigne is the first who inside a printing of the "Oeuvres complétes de Paré (1840-41)" has a fine look upon the question, though his work is incomplete and allows many mistakes. Doctors Chéreau and Jal, an historian, analysing civil status records, gave new information enlarged by doctors Le Paulmier, Turner and the U.S. native Janet Doe.

  5. Passive film growth on carbon steel and its nanoscale features at various passivating potentials

    Energy Technology Data Exchange (ETDEWEB)

    Li, Yuan; Cheng, Y. Frank, E-mail: fcheng@ucalgary.ca

    2017-02-28

    Highlights: • Imaged the topography of passivated steel at various film-forming potentials. • Characterized the nanoscale features of passive films. • Determined the composition of passive films formed at various potentials. - Abstract: In this work, the passivation and topographic sub-structure of passive films on a carbon steel in a carbonate/bicarbonate solution was characterized by electrochemical measurements, atomic force microscopy and X-ray photoelectron spectroscopy. When passivating at a potential near the active-passive transition, the film contains the mixture of Fe{sub 3}O{sub 4}, Fe{sub 2}O{sub 3} and FeOOH, with numerous nanoscale features. As the film-forming potential shifts positively, the passive film becomes more compact and the nanoscale features disappear. When the film is formed at a passive potential where the oxygen evolution is enabled, the content of FeOOH in the film increases, resulting in an amorphous topography and reduced corrosion resistance.

  6. Passivity and passivity breakdown of 304L stainless steel in hot and concentrated nitric acid

    International Nuclear Information System (INIS)

    Gillard-Tcharkhtchi, Elsa

    2014-01-01

    The objective of this study is to characterize the oxidation behavior of 304L stainless steel (SS) in representative conditions of spent nuclear fuel reprocessing, i.e. in hot and concentrated nitric acid. In these conditions the SS electrochemical potential is in the passive domain and its corrosion rate is low. However when the media becomes more aggressive, the potential may be shifted towards the trans-passive domain characterized with a high corrosion rate. Passivity and passivity breakdown in the trans-passive domain are of a major interest for the industry. So as to characterize these phenomenons, this work was undertaken with the following representative conditions: a 304L SS from an industrial sheet was studied, the media was hot and concentrated HNO 3 , long term tests were performed. First, the surface of an immersed 304L SS was characterized with several complementary techniques from the micro to the nanometer scale. Then oxidation kinetics was studied in the passive and in the trans-passive domain. The oxidation behavior was studied thanks to weight loss determination and surface analysis. Finally, oxidation evolution as a function of the potential was studied from the passive to the trans-passive domain. In particular, this allowed us to obtain the anodic curve of 304L SS in hot and concentrated and to define precisely the 304L SS limits of in such conditions. (author) [fr

  7. Keratometric alterations following the 25-gauge transconjunctival sutureless pars plana vitrectomy versus the conventional pars plana vitrectomy.

    Science.gov (United States)

    Citirik, Mehmet; Batman, Cosar; Bicer, Tolga; Zilelioglu, Orhan

    2009-09-01

    To assess the alterations in keratometric astigmatism following the 25-gauge transconjunctival sutureless pars plana vitrectomy versus the conventional pars plana vitrectomy. Sixteen consecutive patients were enrolled into the study. Conventional vitrectomy was applied to eight of the cases and 25-gauge transconjunctival sutureless vitrectomy was performed in eight patients. Keratometry was performed before and after the surgery. In the 25-gauge transconjunctival sutureless pars plana vitrectomy group, statistically significant changes were not observed in the corneal curvature in any post-operative follow-up measurement (p > 0.05); whereas in the conventional pars plana vitrectomy group, statistically significant changes were observed in the first postoperative day (p = 0.01) and first postoperative month (p = 0.03). We noted that these changes returned to baseline in three months (p = 0.26). Both 25-gauge transconjunctival sutureless and conventional pars plana vitrectomy are effective surgical modalities for selected diseases of the posterior segment. Surgical procedures are critical for the visual rehabilitation of the patients. The post-operative corneal astigmatism of the vitrectomised eyes can be accurately determined at least two months post-operatively.

  8. Cyclanthaceae no estado do Pará, Brasil Cyclanthaceae in Pará State, Brazil

    Directory of Open Access Journals (Sweden)

    Eduardo da Silva Leal

    2012-12-01

    Full Text Available Cyclanthaceae apresenta distribuição exclusiva na região neotropical sendo bem diversificada nas terras baixas das florestas pluviais tropicais, ocorrendo do sul do México até a Mata Atlântica do sul do Brasil. Consistem de ervas terrestres, epífitas, hemiepífitas ou lianas. O tratamento taxonômico de Cyclanthaceae no Pará foi baseado em coleções de herbário, trabalhos de campo e consulta a bibliografia referente à família. Foram registradas 11 espécies: Asplundia altiscandens E.S. Leal, A. fanshawei (Maguire Harling, A. glandulosa (Gleason Harling, A. heteranthera Harling, A. latifrons (Drude Harling, A. schizotepala Harling, A. xiphophylla Harling, Cyclanthus bipartitus Poit. ex A. Rich., Evodianthus funifer (Poit. Lindm., Ludovia lancifolia Brongn. e Thoracocarpus bissectus (Vell. Harling. São apresentadas chave de identificação, descrições e ilustrações das espécies, além de comentários sobre distribuição geográfica, hábitat e período de floração e frutificação.Cyclanthaceae is a family with a distribution exclusively in the Neotropics and is well diversified in lowland rainforests, occurring from southern Mexico to the Atlantic Forest of southern Brazil. The family consists of terrestrial herbs, epiphytes, hemiepiphytes and lianas. This taxonomic treatment of the Cyclanthaceae from the state of Pará was based on herbarium specimens, fieldwork, and the literature. Eleven species were recorded: Asplundia altiscandens E.S. Leal, A. fanshawei (Maguire Harling, A. glandulosa (Gleason Harling, A. heteranthera Harling, A. latifrons (Drude Harling, A. schizotepala Harling, A. xiphophylla Harling, Cyclanthus bipartitus Poit. ex A. Rich., Evodianthus funifer (Poit. Lindm., Ludovia lancifolia Brongn. and Thoracocarpus bissectus (Vell. Harling. An identification key, descriptions and illustrations of species are presented. Additional information on the geographic distribution, habitat, and flowering and

  9. Canning by the diffusion caused by a heated die; Gainage par diffusion par filiere chauffante

    Energy Technology Data Exchange (ETDEWEB)

    Gauthron, M [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1959-07-01

    In this process, the uranium fuel is clad with a zirconium can by passing the element through a die. The operation takes place at a temperature varying between 500 and 1000 deg. C. The heating is obtained by passing low voltage electric current through the can. This process differs from the co-extrusion process in that the uranium is not deformed. The uranium is therefore machined to the final dimensions before canning, it can also be hollow. Two types of processes can be adopted for the extrusion: a) Process in which the binding of the can to the uranium is obtained without diffusion (here the can is at high temperature - subsequently cooled - and the uranium is at a low temperature); b) Process in which uranium-zirconium diffusion is initiated. No matter which process is adopted the element is subsequently heat treated in an over at 800 deg. C in order to obtain the final diffusion. The quality of this diffusion is dependent on the initial state of the surfaces and on the degree of vacuum maintained during the operation. (author) [French] Dans ce procede, la gaine zirconium est plaquee sur le combustible uranium par passage dans une filiere. L'operation a lieu a chaud, a une temperature variant entre 500 et 1000 deg. C. Le chauffage est assure par passage d'un courant basse tension dans la gaine. A la difference du procede de cofilage, l'uranium ne subit pas de deformation durant l'operation. Il est donc prealablement usine aux cotes definitives et peut etre creux. Deux processus sont possibles pendant le passage dans la filiere: a) Obtention d'un frettage de la gaine sur l'uranium sans diffusion (avec une gaine a haute temperature et un tube d'uranium a basse temperature, eventuellement refroidi); b) Obtention d'un commencement de diffusion uranium-zirconium. Quelque soit le processus adopte, la cartouche est ensuite traitee dans un four a 800 deg. C pour obtenir la diffusion definitive. La qualite de celle-ci depend essentiellement des etats de surface initiaux

  10. La projection par plasma : une revue

    Science.gov (United States)

    Fauchais, P.; Grimaud, A.; Vardelle, A.; Vardelle, M.

    are presented in the fields of aeronautics and mechanics. La qualité d'un dépôt projete par plasma dépend de nombreux paramètres que l'on commence à mieux appréhender du fait des progrès de la modélisation et de la métrologie tant des écoulements plasmas que des transferts plasma-particules ou que des conditions d'écrasement et de refroidissement des particules lors de leur impact sur le substrat ou les couches déjà déposées. Les techniques de mesure utilisdes et leurs limitations sont d'abord rappelées tant pour les jets de plasma que pour les particules en vol et l'importance des différents phénomènes intervenant dans les transferts plasma-particules est soulignée : gradients de température et de concentration d'espèces chimiques très élevés autour des particules, effets de propagation de la chaleur, notamment pour les particules céramiques, effet d'évaporation, effet de raréfaction sensible dès la pression atmosphérique. Les problèmes de distribution de taille et de vitesse d'injection des particules sont également abordés car ils conditionnent les distributions de trajectoires et donc le traitement des particules dans le jet de plasma. La génération du plasma montre d'une part 1'influence considérable de l'injection du gaz, de sa nature, du dessin de la chambre d'arc et de la tuyère ainsi que du pompage de l'air ambiant sur la longueur des jets de plasma d'arc et d'autre part les problèmes d'injection pour éviter le couplage avec la décharge dans les jets de plasmas R.E Tout ceci est illustré avec des exemples de dépôt d'alumine, de zircone, de cermet carbure et de nickel. L'écrasement des particules est ensuite abordé avec les problèmes de réactions chimiques, de trempe ultra-rapide et donc de structure cristalline des dépôts, d'adhdsion mais aussi de containtes résiduelles et de leur contrôle via les gradients de température dans les dépôts pendant le tir. Enfin quelques applications actuelles sont pr

  11. Passivation of fluorinated activated charcoal

    International Nuclear Information System (INIS)

    Del Cul, G.D.; Trowbridge, L.D.; Simmons, D.W.; Williams, D.F.; Toth, L.M.

    1997-10-01

    The Molten Salt Reactor Experiment (MSRE), at the Oak Ridge National Laboratory has been shut down since 1969 when the fuel salt was drained from the core into two Hastelloy N tanks at the reactor site. In 1995, a multiyear project was launched to remediate the potentially hazardous conditions generated by the movement of fissile material and reactive gases from the storage tanks into the piping system and an auxiliary charcoal bed (ACB). The top 12 in. of the ACB is known by gamma scan and thermal analysis to contain about 2.6 kg U-233. According to the laboratory tests, a few feet of fluorinated charcoal are believed to extend beyond the uranium front. The remainder of the ACB should consist of unreacted charcoal. Fluorinated charcoal, when subjected to rapid heating, can decompose generating gaseous products. Under confined conditions, the sudden exothermic decomposition can produce high temperatures and pressures of near-explosive characteristics. Since it will be necessary to drill and tap the ACB to allow installation of piping and instrumentation for remediation and recovery activities, it is necessary to chemically convert the reactive fluorinated charcoal into a more stable material. Ammonia can be administered to the ACB as a volatile denaturing agent that results in the conversion of the C x F to carbon and ammonium fluoride, NH 4 F. The charcoal laden with NH 4 F can then be heated without risking any sudden decomposition. The only consequence of heating the treated material will be the volatilization of NH 4 F as a mixture of NH 3 and HF, which would primarily recombine as NH 4 F on surfaces below 200 C. The planned scheme for the ACB denaturing is to flow diluted ammonia gas in steps of increasing NH 3 concentration, 2% to 50%, followed by the injection of pure ammonia. This report summarizes the planned passivation treatment scheme to stabilize the ACB and remove the potential hazards. It also includes basic information, results of laboratory tests

  12. Passivation of fluorinated activated charcoal

    Energy Technology Data Exchange (ETDEWEB)

    Del Cul, G.D.; Trowbridge, L.D.; Simmons, D.W.; Williams, D.F.; Toth, L.M.

    1997-10-01

    The Molten Salt Reactor Experiment (MSRE), at the Oak Ridge National Laboratory has been shut down since 1969 when the fuel salt was drained from the core into two Hastelloy N tanks at the reactor site. In 1995, a multiyear project was launched to remediate the potentially hazardous conditions generated by the movement of fissile material and reactive gases from the storage tanks into the piping system and an auxiliary charcoal bed (ACB). The top 12 in. of the ACB is known by gamma scan and thermal analysis to contain about 2.6 kg U-233. According to the laboratory tests, a few feet of fluorinated charcoal are believed to extend beyond the uranium front. The remainder of the ACB should consist of unreacted charcoal. Fluorinated charcoal, when subjected to rapid heating, can decompose generating gaseous products. Under confined conditions, the sudden exothermic decomposition can produce high temperatures and pressures of near-explosive characteristics. Since it will be necessary to drill and tap the ACB to allow installation of piping and instrumentation for remediation and recovery activities, it is necessary to chemically convert the reactive fluorinated charcoal into a more stable material. Ammonia can be administered to the ACB as a volatile denaturing agent that results in the conversion of the C{sub x}F to carbon and ammonium fluoride, NH{sub 4}F. The charcoal laden with NH{sub 4}F can then be heated without risking any sudden decomposition. The only consequence of heating the treated material will be the volatilization of NH{sub 4}F as a mixture of NH{sub 3} and HF, which would primarily recombine as NH{sub 4}F on surfaces below 200 C. The planned scheme for the ACB denaturing is to flow diluted ammonia gas in steps of increasing NH{sub 3} concentration, 2% to 50%, followed by the injection of pure ammonia. This report summarizes the planned passivation treatment scheme to stabilize the ACB and remove the potential hazards. It also includes basic information

  13. Comparative Analysis of Norwegian Passive House Criteria and of Criteria related to the Concept of International Passive House Standard

    DEFF Research Database (Denmark)

    Anton, Karin; Vestergaard, Inge

    2013-01-01

    The analysis shows differences in definition of apssive house criterias. It also communicates issues os the passive house concept that are nor completely transferred by the Norwegian passive house standard.......The analysis shows differences in definition of apssive house criterias. It also communicates issues os the passive house concept that are nor completely transferred by the Norwegian passive house standard....

  14. Parasitisme de Dacryodes edulis par le genre Tapinanthus ...

    African Journals Online (AJOL)

    SARAH

    31 août 2013 ... Parasitisme de Dacryodes edulis par le genre. Tapinanthus (Loranthaceae) et répartition de la myrmécofaune associée à Logbessou Plateau. (Douala, Cameroun). Massako F1*, Tchatat M2, Mony R3, Ladoh Yemeda CF1, Dibong SD1,4,5. 1Laboratoire de Biologie et Physiologie des Organismes ...

  15. Parasitisme des champs semenciers de cacaoyers par les ...

    African Journals Online (AJOL)

    SARAH

    30 janv. 2015 ... J. Appl. Biosci. Parasitisme des champs semenciers de cacaoyers par les loranthaceae dans la localité de Nkoemvone (sud Cameroun). 7795 to the various clones, Phragmanthera capitata was the most abundant Loranthaceae; the level of parasitism of cacao trees is more important at the cacao trees of ...

  16. Den eneste ene - hvordan etniske minoritetsunge i Danmark danner par

    DEFF Research Database (Denmark)

    Singla, Rashmi

    Rapporten handler om etniske unges måde at danne par på. Rapporten er baseret på en større empirisk undersøgelse gennemført af forfatteren i 2003 og er desuden inspireret af forfatterens egen ph.d.-afhandling: "Ungdom, etnicitet og psychosocial intervention" (2000, Københavns Universitet). Rappor...

  17. Indications and visual outcome of first hundred pars plana ...

    African Journals Online (AJOL)

    Objective: To review the indications and visual outcome of the first one hundred pars plana vitrectomies performed at the newly established surgical retina unit of Makkah Specialist Eye Hospital, Kano, Kano State, Nigeria. Materials and Methods: Aretrospective chart review was performed. Data recorded from the patient ...

  18. Epuration des effluents industriels par électroflottation Belkacem ...

    African Journals Online (AJOL)

    étudié la séparation de quelques métaux lourds tels que le fer, le nickel, ... the separation of some heavy metals such as iron, nickel, copper, zinc, lead and ... généralement basées sur l'adsorption (par ... Différents essais de concentration en.

  19. Predicting spectral and PAR light attenuation in Greenlandic coastal waters

    DEFF Research Database (Denmark)

    Murray, Ciarán; Markager, Stiig; Stedmon, Colin

    (CDOM), phytoplankton pigments and inorganic particles. These differences are due in part to hydrography and to the sources of meltwater: respectively, fjord-terminating and land-terminating glaciers. We present a model to explain the variation in spectral and PAR irradiance in terms of the variation...

  20. Priapisme induit par la chlorpromazine: A propos de deux cas

    Directory of Open Access Journals (Sweden)

    I. Marrag

    2016-06-01

    Le priapisme veineux est une urgence urologique. Il constitue un des effets secondaires des neuroleptiques parmi les quels la chlorpromazine. Cet effet iatrogène, qui est rare mais grave, doit être connu par les cliniciens afin d’être mieux prévenu pour éviter les séquelles érectiles.

  1. La lecture de Merleau-Ponty par Renaud Barbaras

    Czech Academy of Sciences Publication Activity Database

    Pechar, Jiří

    2015-01-01

    Roč. 11, č. 2 (2015), s. 1-6 ISSN 1336-6556 Institutional support: RVO:67985955 Keywords : Merleau-Ponty * Husserl * phenomenology * linguistics of Ferdinand de Saussure Subject RIV: AA - Philosophy ; Religion http://www.ostium.sk/sk/la-lecture-de-merleau-ponty-par-renaud-barbaras/

  2. Par Pond vegetation status summer 1995 - July survey descriptive summary

    International Nuclear Information System (INIS)

    Mackey, H.E. Jr.; Riley, R.S.

    1995-07-01

    A survey of the emergent shoreline aquatic plant, communities began in June 1995, three months after the refilling of Par Pond to approximately 200 feet (61 meters) above mean sea level, and continued with this July survey. Aquatic plant communities, similar to the pre-drawdown Par Pond communities, are becoming reestablished. Beds of maidencane (Panicum hemitomon), lotus (Nelumbo lutea), water lily (Nymphaea odorata), and watershield (Brasenia schreberi) are now extensive and well established. In addition, within isolated coves, extensive beds of water lilies and spike-rush (Eleocharis sp.) are common. Cattail occurrence has increased since refill, but large beds common to Par Pond prior to the drawdown have not formed. Invasion of willow (Salix sp.) and red maple (Acer rubrum) occurred along the lake shoreline during drawdown. The red maples along the present shoreline are beginning to show evidence of stress and mortality from flooding over the past four months. Some of the willows appear to be stressed as well. The loblolly pines (Pinus taeda), which were flooded in all but the shallow shoreline areas, are now dead. Future surveys are planned for the growing seasons of 1995, 1996, and 1997, along with the evaluation of satellite data for mapping the areal extent of the macrophyte beds of Par Pond

  3. fortification des farines tropicales par l'introduction de proteines ...

    African Journals Online (AJOL)

    2Université d'Abomey Calavy, Faculté des Sciences et Techniques, Bénin ... valeur recommandée par le Codex Alimentarius pour ce type de complément alimentaire destiné aux enfants. ..... neurotransmission, coagulation sanguine et.

  4. Le développement de l'innovation au profit de l'habitat hautement efficace en énergie : Opportunités et défis liés à l’adoption des maisons passives

    NARCIS (Netherlands)

    Mlecnik, E.

    2013-01-01

    Ces dernières années, nous avons vu une reconnaissance du potentiel significatif qui existe dans la réduction de l’utilisation de l’énergie par le biais de l’innovation dans les logements résidentiels, tout particulièrement les maisons passives. Pour exploiter ce potentiel, nous avons besoin de

  5. Alternative to Nitric Acid Passivation Project Overview

    Science.gov (United States)

    Lewis, Pattie L.

    2013-01-01

    The standard practice for protection of stainless steel is a process called passivation. This procedure results in the formation of a metal oxide layer to prevent corrosion. Typical passivation procedures call for the use of nitric acid which exhibits excellent corrosion performance; however, there are a number of environmental, worker safety, and operational issues associated with its use. The longtime military specification for the passivation of stainless steel was cancelled in favor of newer specifications which allow for the use of citric acid in place of nitric acid. Citric acid offers a variety of benefits that include increased safety for personnel, reduced environmental impact, and reduced operational costs. There have been few studies, however, to determine whether citric acid is an acceptable alternative for NASA and DoD. This paper details activities to date including development of the joint test plan, on-going and planned testing, and preliminary results.

  6. Passive Corrosion Behavior of Alloy 22

    International Nuclear Information System (INIS)

    R.B. Rebak; J.H. Payer

    2006-01-01

    Alloy 22 (NO6022) was designed to stand the most aggressive industrial applications, including both reducing and oxidizing acids. Even in the most aggressive environments, if the temperature is lower than 150 F (66 C) Alloy 22 would remain in the passive state having particularly low corrosion rates. In multi-ionic solutions that may simulate the behavior of concentrated ground water, even at near boiling temperatures, the corrosion rate of Alloy 22 is only a few nano-meters per year because the alloy is in the complete passive state. The corrosion rate of passive Alloy 22 decreases as the time increases. Immersion corrosion testing also show that the newer generation of Ni-Cr-Mo alloys may offer a better corrosion resistance than Alloy 22 only in some highly aggressive conditions such as in hot acids

  7. A Passive Optical Location with Limited Range

    Directory of Open Access Journals (Sweden)

    Pavel Fiala

    2008-01-01

    Full Text Available We know active and passive methods of a location. This article deals only with a passive location of dynamic targets. The passive optics location is suitable just for tracking of targets with mean velocity which is limited by the hardware basis. The aim of this work is to recognize plasma, particles etc. It is possible to propose such kind of evaluation methods which improve the capture probability markedly. Suggested method is dealing with the short-distance evaluation of targets. We suppose the application of three independent principles how to recognize an object in a scanned picture. These principles use similar stochastic functions in order to evaluate an object location by means of simple mathematical operations. Methods are based on direct evaluation of picture sequence by the help of the histogram and frequency spectrum. We find out the probability of unidentified moving object in pictures. If the probability reaches a setting value we will get a signal.

  8. Passive heat removal characteristics of SMART

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Jae Kwang; Kang, Hyung Seok; Yoon, Joo Hyun; Kim, Hwan Yeol; Cho, Bong Hyun [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1998-12-31

    A new advanced integral reactor of 330 MWt thermal capacity named SMART (System-Integrated Modular Advanced Reactor) is currently under development in Korea Atomic Energy Research Institute (KAERI) for multi-purpose applications. Modular once-through steam generator (SG) and self-pressurizing pressurizer equipped with wet thermal insulator and cooler are essential components of the SMART. The SMART provides safety systems such as Passive Residual Heat Removal System (PRHRS). In this study, a computer code for performance analysis of the PRHRS is developed by modeling relevant components and systems of the SMART. Using this computer code, a performance analysis of the PRHRS is performed in order to check whether the passive cooling concept using the PRHRS is feasible. The results of the analysis show that PRHRS of the SMART has excellent passive heat removal characteristics. 2 refs., 4 figs., 1 tab. (Author)

  9. Protocol Monitoring Passive Solar Energy. Background document

    International Nuclear Information System (INIS)

    Van den Ham, E.R.

    1998-01-01

    A method has been developed by means of which the contribution of passive solar energy to the Dutch energy balance can be quantified univocally. The monitoring will be directed at the absolute amount of used solar energy, the relative contribution of passive solar energy to the energy demand in the Netherlands, and the average efficiency of passive solar energy systems. Based on a model of the total building stock the quantities to be monitored can be determined. The most important parameters in the model are: the window surface per orientation, the average U-value (heat transfer coefficient) of windows, the average ZTA-value (incoming solar radiation factor) of windows, and the presence of sun lounges and atriums

  10. Climate-Specific Passive Building Standards

    Energy Technology Data Exchange (ETDEWEB)

    Wright, Graham S. [Passive House Inst., Westford, MA (United States); Klingenberg, Katrin [Passive House Inst., Westford, MA (United States)

    2015-07-01

    Passive design principles (super insulation, airtight envelopes, elimination of thermal bridges, etc.) - pioneered in North America in the 70s and 80s and refined in Europe in the 90s have proven to be universally effective to significantly reduce heating and cooling loads. However, a single, rigid performance metric developed in Germany has led to limited uptake of passive building principles in many regions of the United States. It has also, in many cases, promoted some design decisions that had negative effects on economic feasibility and thermal comfort. This study's main objective is to validate (in a theoretical sense) verifiable, climate-specific passive standards and space conditioning criteria that retain ambitious, environmentally-necessary energy reduction targets and are economically feasible, such standards provide designers an ambitious but achievable performance target on the path to zero.

  11. A passive sampler for atmospheric ozone

    International Nuclear Information System (INIS)

    Grosjean, D.; Hisham, M.W.M.

    1992-01-01

    A simple, cost-effective passive sampler has been developed for the determination of atmospheric ozone. This passive sampler is based on a colorant which fades upon reaction with ozone, whose concentration can be determined by reflectance measurement of the color change. Direct, on-site measurements are possible, and no chemical analyses are needed. Sampler design and validation studies have been carried out and included quantitative determination of color change vs exposure time (1-8 days), color change vs. ozone concentration (30-350 ppb), and response to changes in sampler configuration that modify the passive sampling rate. With indigo carmine as the colorant, the detection limits are 30 ppb. day and 120 ppb. day using a plastic grid and Teflon filter, respectively, as diffusion barriers. Interferences from nitrogen dioxide, formaldehyde and peroxyacetyl nitrate are 15, 4 and 16%, respectively, thus resulting in a negligible bias when measuring ozone in ambient air

  12. High-order passive photonic temporal integrators.

    Science.gov (United States)

    Asghari, Mohammad H; Wang, Chao; Yao, Jianping; Azaña, José

    2010-04-15

    We experimentally demonstrate, for the first time to our knowledge, an ultrafast photonic high-order (second-order) complex-field temporal integrator. The demonstrated device uses a single apodized uniform-period fiber Bragg grating (FBG), and it is based on a general FBG design approach for implementing optimized arbitrary-order photonic passive temporal integrators. Using this same design approach, we also fabricate and test a first-order passive temporal integrator offering an energetic-efficiency improvement of more than 1 order of magnitude as compared with previously reported passive first-order temporal integrators. Accurate and efficient first- and second-order temporal integrations of ultrafast complex-field optical signals (with temporal features as fast as approximately 2.5ps) are successfully demonstrated using the fabricated FBG devices.

  13. Passivated emitters in silicon solar cells

    International Nuclear Information System (INIS)

    King, R.R.; Gruenbaum, P.E.; Sinton, R.A.; Swanson, R.M.

    1990-01-01

    In high-efficiency silicon solar cells with low metal contact coverage fractions and high bulk lifetimes, cell performance is often dominated by recombination in the oxide-passivated diffusions on the cell surface. Measurements of the emitter saturation current density, J o , of oxide-passivated, boron and phosphorus diffusions are presented, and from these measurements, the dependence of surface recombination velocity on dopant concentration was extracted. The lowest observed values of J o which are stable under UV light are given for both boron- and phosphorus-doped, oxide-passivated diffusions, for both textured and untextured surfaces. Contour plots which incorporate the above data have been applied to two types of backside-contact solar cells with large area (37.5 cm 2 ) and one-sun efficiencies up to 22.7%

  14. The role of pars flaccida in human middle ear sound transmission.

    Science.gov (United States)

    Aritomo, H; Goode, R L; Gonzalez, J

    1988-04-01

    The role of the pars flaccida in middle ear sound transmission was studied with the use of twelve otoscopically normal, fresh, human temporal bones. Peak-to-peak umbo displacement in response to a constant sound pressure level at the tympanic membrane was measured with a noncontacting video measuring system capable of repeatable measurements down to 0.2 micron. Measurements were made before and after pars flaccida modifications at 18 frequencies between 100 and 4000 Hz. Four pars flaccida modifications were studied: (1) acoustic insulation of the pars flaccida to the ear canal with a silicone rubber baffle, (2) stiffening the pars flaccida with cyanoacrylate cement, (3) decreasing the tension of the pars flaccida with a nonperforating incision, and (4) perforation of the pars flaccida. All of the modifications (except the perforation) had a minimal effect on umbo displacement; this seems to imply that the pars flaccida has a minor acoustic role in human beings.

  15. TEPSS - Technology Enhancement for Passive Safety Systems

    International Nuclear Information System (INIS)

    Hart, J.; Slegers, W.J.M.; Boer, S.L. de; Huggenberger, M.; Lopez Jimenez, J.; Munoz-Cabo Gonzalez, J.L.; Reventos Puigjaner, F.

    2000-01-01

    The objective of the TEPSS project was to make significant additions to the technology base of the European Simplified Boiling Water Reactor (ESBWR). The project focused on mixing and stratification phenomena in large water pools, passive decay heat removal from containments, and effects of aerosol deposition inside a passive heat exchanger. The PSI experimental facility LINX (Large-scale Investigation of Natural Circulation and Mixing) has been used to investigate venting of steam and steam-noncondensable gas mixtures into water pools. The test revealed that no significant steam bypass could be detected when injecting a mixture of steam or air and that mixing was very efficient. In addition to the tests, 3-D numerical computations and initial model development have been performed to study the behaviour of bubble plumes in water pools. The major part of the TEPSS project studied selective aspects of the response technology of modem pressure-suppression type containment designs and of passive-type decay heat removal systems. The work included an experimental phase using the large-scale experimental facility PANDA (Passive Nachwaermeabfuhr und Druckabbau), operated by PSI, where eight experiments successfully have been executed to test the performance of the ESBWR containment configuration. The PANDA tests have been analysed successfully using thermalhydraulic system analysis codes and 3-D CFD codes. The AIDA (Aerosol Impaction and Deposition Analysis) experimental facility of PSI has been used to investigate the degradation of passive decay heat removal due to fission product aerosols deposited on the inside surfaces of the PCC (Passive Containment Cooler) heat exchanger tubes. The one test performed revealed that the degradation of the heat transfer in the PCC tubes due to the deposition of aerosols reached about 20%. The test has been analysed using the MELCOR severe accident analysis code. (author)

  16. Fast New Method for Temporary Chemical Passivation

    Directory of Open Access Journals (Sweden)

    Marek Solčanský

    2012-12-01

    Full Text Available The main material parameter of silicon, that influences the effectiveness of photovoltaic cells, is the minority carrier bulk lifetime.It may change in the technological process especially during high temperature operations. Monitoring of the carrier bulk-lifetimeis necessary for modifying the whole technological process of production. For the measurement of the minority carrier bulk-lifetimethe characterization method MW PCD (Microwave Photoconductance Decay is used, where the result of measurement is the effectivecarrier lifetime, which is very dependent on the surface recombination velocity and therefore on the quality of a silicon surfacepassivation.This work deals with an examination of a different solution types for the chemical passivation of a silicon surface. Varioussolutions are tested on silicon wafers for their consequent comparison. The main purpose of this work is to find optimal solution, whichsuits the requirements of a time stability and start-up velocity of passivation, reproducibility of the measurements and a possibilityof a perfect cleaning of a passivating solution remains from a silicon surface. Another purpose of this work is to identify the parametersof other quinhydrone solutions with different concentrations as compared with the quinhydrone solution in methanol witha concentration of 0.07 mol/dm³ marked QM007 (referential solution.The method of an effective chemical passivation with a quinhydrone in methanol solution was suggested. The solution witha concentration of 0.07 mol /dm3 fulfills all required criteria. The work also confirms the influence of increased concentrationquinhydrone on the temporal stability of the passivation layer and the effect for textured silicon wafers. In conclusion, the influenceof an illumination and the temperature on the properties of the passivating solution QM007 is discussed.

  17. Passive remediation strategies for petroleum contaminated sites

    International Nuclear Information System (INIS)

    Everett, L.G.; Cullen, S.J.; Eccles, L.A.

    1991-01-01

    The US EPA is becoming increasingly aware of costs and the limited success of existing remediation strategies. Research teams within the US EPA believe that if passive remediation can be successfully demonstrated, it is a candidate for best available technology. Passive remediation, however, must be demonstrated through the use of monitoring techniques, which demonstrate: contaminants are not moving in the dissolved, adsorbed or free product phase; and contamination is biodegrading in-place. This paper presents a concise monitoring and analysis strategy for passive remediation. Specifically, the paper presents the accuracy, precision and operating range of neutron moderation techniques as a low cost, real-time screening tool to measure the migration of the dissolved phase in soil moisture, the stabilized adsorbed phase and free product movement. In addition, the paper identifies the capillary pressure range through which the dissolved phase will move and identifies techniques for satisfying the risk analysis that movement is not taking place. The rationale for passive remediation taking place is confirmed through a discussion of gas ratios associated with bacterial assimilation of hydrocarbons. Gas ratios which are relatively constant above ground are highly inverted in the subsurface at contamination sites. The use of frequent screening of a vertical geologic profile using least cost techniques and the infrequent analysis of soil gas ratios provides the required data upon which the public will accept passive remediation as best available technology at a particular site. The paper points out that neutron moderation is a high candidate vadose zone monitoring device and identifies alternative techniques using resistivity and dielectric constants, which are in the developmental stage. The economic implications for passive remediation are enormous relative to the excavation and remediation strategies which are currently in use

  18. Study on diverse passive decay heat removal approach

    International Nuclear Information System (INIS)

    Lin Qian; Si Shengyi

    2012-01-01

    One of the most important principles for nuclear safety is the decay heat removal in accidents. Passive decay heat removal systems are extremely helpful to enhance the safety. In currently design of many advanced nuclear reactors, kinds of passive systems are proposed or developed, such as the passive residual heat removal system, passive injection system, passive containment cooling system. These systems provide entire passive heat removal paths from core to ultimate heat sink. Various kinds of passive systems for decay heat removal are summarized; their common features or differences on heat removal paths and design principle are analyzed. It is found that, these passive decay heat removal paths are similarly common on and connected by several basic heat transfer modes and steps. By the combinations or connections of basic modes and steps, new passive decay heat removal approach or diverse system can be proposed. (authors)

  19. Inherently safe passive gas monitoring system

    Energy Technology Data Exchange (ETDEWEB)

    Cordaro, Joseph V.; Bellamy, John Stephen; Shuler, James M.; Shull, Davis J.; Leduc, Daniel R.

    2016-09-06

    Generally, the present disclosure is directed to gas monitoring systems that use inductive power transfer to safely power an electrically passive device included within a nuclear material storage container. In particular, the electrically passive device can include an inductive power receiver for receiving inductive power transfer through a wall of the nuclear material storage container. The power received by the inductive power receiver can be used to power one or more sensors included in the device. Thus, the device is not required to include active power generation components such as, for example, a battery, that increase the risk of a spark igniting flammable gases within the container.

  20. Passive Polarimetric Information Processing for Target Classification

    Science.gov (United States)

    Sadjadi, Firooz; Sadjadi, Farzad

    Polarimetric sensing is an area of active research in a variety of applications. In particular, the use of polarization diversity has been shown to improve performance in automatic target detection and recognition. Within the diverse scope of polarimetric sensing, the field of passive polarimetric sensing is of particular interest. This chapter presents several new methods for gathering in formation using such passive techniques. One method extracts three-dimensional (3D) information and surface properties using one or more sensors. Another method extracts scene-specific algebraic expressions that remain unchanged under polariza tion transformations (such as along the transmission path to the sensor).

  1. Piping reliability improvement through passive seismic supports

    International Nuclear Information System (INIS)

    Baltus, R.; Rubbers, A.

    1999-01-01

    The nuclear plants designed in the 1970's were equipped with large quantities of snubbers in auxiliary piping systems. The experience revealed a poor performance of snubbers during periodic inspection, while non-nuclear facility piping survived through strong earthquakes. Consequently, seismic design rules evolved towards more realistic criteria and passive dynamic supports were developed to reduce snubber quantities. These solutions improve the pipe reliability during normal operation while reducing the radiation exposure in a sample line is presented with the impact on pipe stresses compared to the results obtained with passive supports named Limit Stops. (author)

  2. Superacid Passivation of Crystalline Silicon Surfaces.

    Science.gov (United States)

    Bullock, James; Kiriya, Daisuke; Grant, Nicholas; Azcatl, Angelica; Hettick, Mark; Kho, Teng; Phang, Pheng; Sio, Hang C; Yan, Di; Macdonald, Daniel; Quevedo-Lopez, Manuel A; Wallace, Robert M; Cuevas, Andres; Javey, Ali

    2016-09-14

    The reduction of parasitic recombination processes commonly occurring within the silicon crystal and at its surfaces is of primary importance in crystalline silicon devices, particularly in photovoltaics. Here we explore a simple, room temperature treatment, involving a nonaqueous solution of the superacid bis(trifluoromethane)sulfonimide, to temporarily deactivate recombination centers at the surface. We show that this treatment leads to a significant enhancement in optoelectronic properties of the silicon wafer, attaining a level of surface passivation in line with state-of-the-art dielectric passivation films. Finally, we demonstrate its advantage as a bulk lifetime and process cleanliness monitor, establishing its compatibility with large area photoluminescence imaging in the process.

  3. Passive cooling systems in power reactors

    International Nuclear Information System (INIS)

    Aharon, J.; Harrari, R.; Weiss, Y.; Barnea, Y.; Katz, M.; Szanto, M.

    1996-01-01

    This paper reviews several R and D activities associated with the subject of passive cooling systems, conducted by the N.R.C.Negev thermohydraulic group. A short introduction considering different types of thermosyphons and their applications is followed by a detailed description of the experimental work, its results and conclusions. An ongoing research project is focused on the evaluation of the external dry air passive containment cooling system (PCCS) in the AP-600 (Westinghouse advanced pressurized water reactor). In this context some preliminary theoretical results and planned experimental research are for the fature described

  4. Passive cooling in modern nuclear reactors

    International Nuclear Information System (INIS)

    Rouai, N. M.

    1998-01-01

    This paper presents some recent experimental results performed with the aim of understanding the mechanism of passive cooling. The AP 600 passive containment cooling system is simulated by an electrically heated vertical pipe, which is cooled by a naturally induced air flow and by a water film descending under gravity. The results demonstrate that although the presence of the water film improved the heat transfer significantly, the mode of heat transfer was very dependent on the experimental parameters. Preheating the water improved both film stability and overall cooling performance

  5. An all-silicon passive optical diode.

    Science.gov (United States)

    Fan, Li; Wang, Jian; Varghese, Leo T; Shen, Hao; Niu, Ben; Xuan, Yi; Weiner, Andrew M; Qi, Minghao

    2012-01-27

    A passive optical diode effect would be useful for on-chip optical information processing but has been difficult to achieve. Using a method based on optical nonlinearity, we demonstrate a forward-backward transmission ratio of up to 28 decibels within telecommunication wavelengths. Our device, which uses two silicon rings 5 micrometers in radius, is passive yet maintains optical nonreciprocity for a broad range of input power levels, and it performs equally well even if the backward input power is higher than the forward input. The silicon optical diode is ultracompact and is compatible with current complementary metal-oxide semiconductor processing.

  6. Passive containment system for a nuclear reactor

    International Nuclear Information System (INIS)

    Kleimola, F.W.

    1976-01-01

    A containment system is described that provides complete protection entirely by passive means for the loss of coolant accident in a nuclear power plant and wherein all stored energy released in the coolant blowdown is contained and absorbed while the nuclear fuel is continuously maintained submerged in liquid. The primary containment vessel is restored to a high subatmospheric pressure within a few minutes after accident initiation and the decay heat is safely transferred to the environment while radiolytic hydrogen is contained by passive means

  7. The passive diffusion of Leptospira interrogans

    International Nuclear Information System (INIS)

    Koens, Lyndon; Lauga, Eric

    2014-01-01

    Motivated by recent experimental measurements, the passive diffusion of the bacterium Leptospira interrogans is investigated theoretically. By approximating the cell shape as a straight helix and using the slender-body-theory approximation of Stokesian hydrodynamics, the resistance matrix of Leptospira is first determined numerically. The passive diffusion of the helical cell is then obtained computationally using a Langevin formulation which is sampled in time in a manner consistent with the experimental procedure. Our results are in excellent quantitative agreement with the experimental results with no adjustable parameters. (paper)

  8. The passive diffusion of Leptospira interrogans

    Science.gov (United States)

    Koens, Lyndon; Lauga, Eric

    2014-12-01

    Motivated by recent experimental measurements, the passive diffusion of the bacterium Leptospira interrogans is investigated theoretically. By approximating the cell shape as a straight helix and using the slender-body-theory approximation of Stokesian hydrodynamics, the resistance matrix of Leptospira is first determined numerically. The passive diffusion of the helical cell is then obtained computationally using a Langevin formulation which is sampled in time in a manner consistent with the experimental procedure. Our results are in excellent quantitative agreement with the experimental results with no adjustable parameters.

  9. Passive heat transport in advanced CANDU containment

    International Nuclear Information System (INIS)

    Krause, M.; Mathew, P.M.

    1994-01-01

    A passive CANDU containment design has been proposed to provide the necessary heat removal following a postulated accident to maintain containment integrity. To study its feasibility and to optimize the design, multi-dimensional containment modelling may be required. This paper presents a comparison of two CFD codes, GOTHIC and PHOENICS, for multi-dimensional containment analysis and gives pressure transient predictions from a lumped-parameter and a three-dimensional GOTHIC model for a modified CANDU-3 containment. GOTHIC proved suitable for multidimensional post-accident containment analysis, as shown by the good agreement with pressure transient predictions from PHOENICS. GOTHIC is, therefore, recommended for passive CANDU containment modelling. (author)

  10. Technical Assessment: WRAP 1 HVAC Passive Shutdown

    International Nuclear Information System (INIS)

    Ball, D.E.; Nash, C.R.; Stroup, J.L.

    1993-01-01

    As the result of careful interpretation of DOE Order 6430.lA and other DOE Orders, the HVAC system for WRAP 1 has been greatly simplified. The HVAC system is now designed to safely shut down to Passive State if power fails for any reason. The fans cease functioning, allowing the Zone 1 and Zone 2 HVAC Confinement Systems to breathe with respect to atmospheric pressure changes. Simplifying the HVAC system avoided overdesign. Construction costs were reduced by eliminating unnecessary equipment. This report summarizes work that was done to define the criteria, physical concepts, and operational experiences that lead to the passive shutdown design for WRAP 1 confinement HVAC systems

  11. Perfect and Periphrastic Passive Constructions in Danish

    DEFF Research Database (Denmark)

    Bjerre, Tavs; Bjerre, Anne

    2007-01-01

    This paper gives an account of the event and argument structure of past participles and the linking between argument structure and valence structure. It further accounts for how participles form perfect and passiv constructions with auxiliaries. We assume that the same participle form is used...... in both types of construction. Our claim is that the valence structure of a past participle is predictable from its semantic type, and that the valence structure predicts with which auciliary a past participle combines in perfect constructions and whether the past participle may occur in passiv...

  12. Aktive og passive valg i pensionsopsparingen

    DEFF Research Database (Denmark)

    Nielsen, Torben Heien

    2017-01-01

    This paper reviews two papers from my own research. I show that the effect of pension policies are highly dependent on which type of decision maker the policy targets. Specifically, the effectiveness of the policy is stronger if it affects passive choice. Such policies, e.g., employer pensions......, are extremely effective in increasing total individual savings. Tax deductions on the other hand are ineffective. The reason is that an estimated 85 % of the population are passive savers, who do not respond to changes in policies. Consequently, an increased labor market pension rate will also make their total...

  13. Primordial black holes from passive density fluctuations

    International Nuclear Information System (INIS)

    Lin, Chia-Min; Ng, Kin-Wang

    2013-01-01

    In this Letter, we show that if passive fluctuations are considered, primordial black holes (PBHs) can be easily produced in the framework of single-field, slow-roll inflation models. The formation of PBHs is due to the blue spectrum of passive fluctuations and an enhancement of the spectral range which exits horizon near the end of inflation. Therefore the PBHs are light with masses ≲10 15 g depending on the number of e-folds when the scale of our observable universe leaves horizon. These PBHs are likely to have evaporated and cannot be a candidate for dark matter but they may still affect the early universe.

  14. Primordial black holes from passive density fluctuations

    OpenAIRE

    Lin, Chia-Min; Ng, Kin-Wang

    2013-01-01

    In this paper, we show that if passive fluctuations are considered, primordial black holes (PBHs) can be easily produced in the framework of single-field, slow-roll inflation models. The formation of PBHs is due to the blue spectrum of passive fluctuations and an enhancement of the spectral range which exits horizon near the end of inflation. Therefore the PBHs are light with masses $\\lesssim 10^{15}g$ depending on the number of e-folds when the scale of our observable universe leaves horizon...

  15. Passive Smoking in a Displacement Ventilated Room

    DEFF Research Database (Denmark)

    Bjørn, Erik; Nielsen, Peter V.

    The aim of this research is to see if the displacement ventilation principle can protect a person from exposure to passive tobacco smoking. This is done by full-scale experiments with two breathing thermal manikins, smoke visualisations, and tracer gas measurements. In some situations, exhaled...... smoke will stratify in a certain height due to the vertical temperature gradient. This horizontal layer of exhaled tobacco smoke may lead to exposure. In other situations, the smoke is mixed into the upper zone, and the passive smoker is protected to some extent by the displacement principle...

  16. Apoplejía pituitaria con parálisis del III par craneal: Reporte de caso

    Directory of Open Access Journals (Sweden)

    Miguel Pinto Valdivia

    2011-10-01

    Full Text Available Se describe el caso de un varón de 65 años de edad, sin antecedentes patológicos de importancia, que acudió a emergencia del Hospital Nacional Cayetano Heredia por presentar cefalea intensa y ptosis palpebral izquierda. El examen físico mostró parálisis aislada del III par craneal izquierdo. Los análisis de laboratorio mostraron hiponatremia e hipopituitarismo y la resonancia magnética nuclear un adenoma pituitario con áreas de hemorragia e invasión de los senos cavernosos. El tratamiento incluyó glucocorticoides y descompresión quirúrgica transesfenoidal. La anatomía patológica confirmó el diagnóstico de infarto hemorrágico de un adenoma pituitario. El paciente fue dado de alta con terapia sustitutiva de levotiroxina y prednisona. La ptosis palpebral izquierda se recuperó en forma parcial. La apoplejía pituitaria es un síndrome clínico producido por un proceso expansivo dentro de la silla turca, secundario a hemorragia o infarto de un adenoma pituitario, que se caracteriza por cefalea, déficit visual, oftalmoplejía y alteración del nivel de conciencia. Este proceso expansivo puede comprimir los pares craneales en los senos cavernosos, produciendo diferentes grados de parálisis de los músculos oculomotores. La parálisis aislada del III par craneal es rara.(Rev Med Hered 2011;22:186-189.

  17. Épidémiologie de l'intoxication par envenimation chez les enfants ...

    African Journals Online (AJOL)

    Introduction: L'intoxication par envenimation est l'ensemble des manifestations locales et générales induites par la pénétration dans l'organisme d'une substance toxique produite par un animal venimeux. Le but de notre travail était d'étudier les signes cliniques des intoxications par envenimation chez les enfants de 0 à 15 ...

  18. THE USE OF PASSIVE SOLAR HEATING SYSTEMS AS PART OF THE PASSIVE HOUSE

    Directory of Open Access Journals (Sweden)

    Bryzgalin Vladislav Viktorovich

    2018-05-01

    Full Text Available Subject: systems of passive solar heating, which can, without the use of engineering equipment, capture and accumulate the solar heat used for heating buildings. Research objectives: study of the possibility to reach the passive house standard (buildings with near zero energy consumption for heating in climatic conditions of Russia using the systems of passive solar heating in combination with other solutions for reduction of energy costs of building developed in the past. Materials and methods: search and analysis of literature, containing descriptions of various passive solar heating systems, examples of their use in different climatic conditions and the resulting effect obtained from their use; analysis of thermophysical processes occurring in these systems. Results: we revealed the potential of using the solar heating systems in the climatic conditions of parts of the territories of the Russian Federation, identified the possibility of cheaper construction by the passive house standard with the use of these systems. Conclusions: more detailed analysis of thermophysical and other processes that take place in passive solar heating systems is required for creation of their computational models, which will allow us to more accurately predict their effectiveness and seek the most cost-effective design solutions, and include them in the list of means for achieving the passive house standard.

  19. Soluble urokinase plasminogen activator receptor (suPAR) in acute care

    DEFF Research Database (Denmark)

    Rasmussen, Line Jee Hartmann; Ladelund, Steen; Haupt, Thomas Huneck

    2016-01-01

    for age, sex, Charlson score and C reactive protein. Area under the curve for receiver operating characteristics curve analysis of suPAR for 30-day mortality was 0.84 (95% CI 0.81 to 0.86). Furthermore, in the entire cohort, women had slightly higher suPAR compared with men, and suPAR was associated...

  20. Movement and equipositioning of plasmids by ParA filament disassembly

    DEFF Research Database (Denmark)

    Ringgaard, Simon; van Zon, Jeroen; Howard, Martin

    2009-01-01

    , plasmids consistently migrate behind disassembling ParA cytoskeletal structures, suggesting that ParA filaments pull plasmids by depolymerization. The perpetual cycles of ParA assembly and disassembly result in continuous relocation of plasmids, which, on time averaging, results in equidistribution...

  1. Protease-Activated Receptor 4 (PAR4): A Promising Target for Antiplatelet Therapy.

    Science.gov (United States)

    Rwibasira Rudinga, Gamariel; Khan, Ghulam Jilany; Kong, Yi

    2018-02-14

    Cardiovascular diseases (CVDs) are currently among the leading causes of death worldwide. Platelet aggregation is a key cellular component of arterial thrombi and major cause of CVDs. Protease-activated receptors (PARs), including PAR1, PAR2, PAR3 and PAR4, fall within a subfamily of seven-transmembrane G-protein-coupled receptors (GPCR). Human platelets express PAR1 and PAR4, which contribute to the signaling transduction processes. In association with CVDs, PAR4 not only contributes to platelet activation but also is a modulator of cellular responses that serve as hallmarks of inflammation. Although several antiplatelet drugs are available on the market, they have many side effects that limit their use. Emerging evidence shows that PAR4 targeting is a safer strategy for preventing thrombosis and consequently may improve the overall cardiac safety profile. Our present review summarizes the PAR4 structural characteristics, activation mechanism, role in the pathophysiology of diseases and understanding the association of PAR4 targeting for improved cardiac protection. Conclusively, this review highlights the importance of PAR4 antagonists and its potential utility in different CVDs.

  2. Protease-Activated Receptor 4 (PAR4: A Promising Target for Antiplatelet Therapy

    Directory of Open Access Journals (Sweden)

    Gamariel Rwibasira Rudinga

    2018-02-01

    Full Text Available Cardiovascular diseases (CVDs are currently among the leading causes of death worldwide. Platelet aggregation is a key cellular component of arterial thrombi and major cause of CVDs. Protease-activated receptors (PARs, including PAR1, PAR2, PAR3 and PAR4, fall within a subfamily of seven-transmembrane G-protein-coupled receptors (GPCR. Human platelets express PAR1 and PAR4, which contribute to the signaling transduction processes. In association with CVDs, PAR4 not only contributes to platelet activation but also is a modulator of cellular responses that serve as hallmarks of inflammation. Although several antiplatelet drugs are available on the market, they have many side effects that limit their use. Emerging evidence shows that PAR4 targeting is a safer strategy for preventing thrombosis and consequently may improve the overall cardiac safety profile. Our present review summarizes the PAR4 structural characteristics, activation mechanism, role in the pathophysiology of diseases and understanding the association of PAR4 targeting for improved cardiac protection. Conclusively, this review highlights the importance of PAR4 antagonists and its potential utility in different CVDs.

  3. Par3L enhances colorectal cancer cell survival by inhibiting Lkb1/AMPK signaling pathway

    International Nuclear Information System (INIS)

    Li, Taiyuan; Liu, Dongning; Lei, Xiong; Jiang, Qunguang

    2017-01-01

    Partitioning defective 3-like protein (Par3L) is a recently identified cell polarity protein that plays an important role in mammary stem cell maintenance. Previously, we showed that high expression of Par3L is associated with poor survival in malignant colorectal cancer (CRC), but the underlying mechanism remained unknown. To this end, we established a Par3L knockout colorectal cancer cell line using the CRISPR/Cas system. Interestingly, reduced proliferation, enhanced cell death and caspase-3 activation were observed in Par3L knockout (KO) cells as compared with wildtype (WT) cells. Consistent with previous studies, we showed that Par3L interacts with a tumor suppressor protein liver kinase B1 (Lkb1). Moreover, Par3L depletion resulted in abnormal activation of Lkb1/AMPK signaling cascade. Knockdown of Lkb1 in these cells could significantly reduce AMPK activity and partially rescue cell death caused by Par3L knockdown. Furthermore, we showed that Par3L KO cells were more sensitive to chemotherapies and irradiation. Together, these results suggest that Par3L is essential for colorectal cancer cell survival by inhibiting Lkb1/AMPK signaling pathway, and is a putative therapeutic target for CRC. - Highlights: • Par3L knockout using the CRISPR/Cas system induces apoptosis in colorectal cancer cells. • Par3L interacts with Lkb1 and regulates the activity of AMPK signaling cascade. • Par3L knockout cells are more sensitive to treatment of different chemotherapy drugs and irradiation.

  4. Brésil : La contamination par le mercure en Amazonie | CRDI ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    11 janv. 2011 ... En tentant de déceler la source de la contamination de l'Amazone par le ... par Jean-Rémy Davy Guimaraes de l'Université fédérale de Rio de Janeiro ... ces mattes est circonscrite par la conservation et la restauration en rive.

  5. Passive cyclotron current drive for fusion plasmas

    International Nuclear Information System (INIS)

    Kernbichler, W.

    1995-01-01

    The creation of toroidal current using cyclotron radiation in a passive way is, together with the well known bootstrap current, an interesting method for stationary current drive in high-temperature fusion reactors. Here, instead of externally applied RF-waves, fish-scale like structures at the first wall help to create enough asymmetry in the self generated cyclotron radiation intensity to drive a current within the plasma. The problem of computing passive cyclotron current drive consists of actually two linked problems, which are the computation of the electron equilibrium under the presence of self-generated radiation, and the computation of the photon equilibrium in a bounded system with a distorted electron distribution. This system of integro-differential equations cannot be solved directly in an efficient way. Therefore a linearization procedure was developed to decouple both sets of equations, finally linked through a generalized local current drive efficiency. The problem of the exact accounting for the wall profile effects was reduced to the solution of a Fredholm-type integral equation of the 2 nd -kind. Based on all this an extensive computer code was developed to compute the passively driven current as well as radiation losses, radiation transport and overall efficiencies. The results therefrom give an interesting and very detailed insight into the problems related to passive cyclotron current drive

  6. [The consequences of passive smoking in adults].

    Science.gov (United States)

    Trédaniel, J; Savinelli, F; Vignot, S; Bousquet, G; Le Maignan, C; Misset, J-L

    2006-04-01

    Passive smoking is the involuntary inhalation by a non-smoker of smoke generated in his neighbourhood by one or more smokers. The effect of this exposure is already generally recognised in children. In adults the induction of chronic obstructive lung disease has not been demonstrated. This is no longer the case for ischaemic heart disease and lung cancer where the effect of passive exposure of non-smokers to cigarette smoke is recognised. The biological plausibility together with the concordance of results obtained over successive years, as well as the large numbers of patients included in the studies, lead to a confident conclusion that the risks in adult non-smokers are increased by the order of 25%. There is no evidence that bias affects the conclusions reached and the World Health Organisation has recently classified passive smoking as being carcinogenic in man. As a result of these data prevention of passive exposure to cigarette smoke should be part of a larger framework of smoking prevention, especially among the young.

  7. Surface Passivation for Silicon Heterojunction Solar Cells

    NARCIS (Netherlands)

    Deligiannis, D.

    2017-01-01

    Silicon heterojunction solar cells (SHJ) are currently one of the most promising solar cell technologies in the world. The SHJ solar cell is based on a crystalline silicon (c-Si) wafer, passivated on both sides with a thin intrinsic hydrogenated amorphous silicon (a-Si:H) layer. Subsequently, p-type

  8. Recent Developments in SOBEK Passive Sonar Technology

    NARCIS (Netherlands)

    Hunter, A.J.; Fillinger, L.; Zampolli, M.; Clarijs, M.C.

    2012-01-01

    Surveillance of waterside locations for protection against threats from small fast surface vessels and underwater intruders is a very relevant but challenging problem. For this reason, the Netherlands Organisation for Applied Scientific Research (TNO) is developing SOBEK – a family of passive sonar

  9. The MEMOLED: Active addressing with passive driving

    NARCIS (Netherlands)

    Asadi, K.; Blom, P.W.M.; Leeuw, D.M. de

    2011-01-01

    Passive or active matrix driving schemes in large displays are prone to high power consumption and cost, respectively. For signage applications such as large out-door displays with low refresh rates there is as yet no technological solution. Here the MEMOLED solution, an organic light-emitting diode

  10. The MEMOLED : Active Addressing with Passive Driving

    NARCIS (Netherlands)

    Asadi, Kamal; Blom, Paul W. M.; de Leeuw, Dago M.

    2011-01-01

    Passive or active matrix driving schemes in large displays are prone to high power consumption and cost, respectively. For signage applications such as large outdoor displays with low refresh rates there is as yet no technological solution. Here the MEMOLED solution, an organic light-emitting diode

  11. NucleDyne's passive containment system

    International Nuclear Information System (INIS)

    Falls, O.B. Jr.; Kleimola, F.W.

    1987-01-01

    A simple definition of the passive containment system is that it is a total safeguards system for light water reactors designed to prevent and contain any accidental release of radioactivity. Its passive features utilize the natural laws of physics and thermodynamics. The system encompasses three basic containments constructed as one integrated structure on the reactor building foundation. The primary containment encloses the reactor pressure vessel and coolant system and passive engineered safety systems and components. Auxiliary containment enclosures house auxiliary systems and components. Secondary containment (the reactor building), housing the primary and auxiliary containment structures, provides a second containment barrier as added defense-in-depth against leakage of radioactivity for all accidents assumed by the industry. The generic features of the passive containment system are applicable to both the boiling water reactors and the pressurized water reactors as standardized features for all power ranges. These features provide for a zero source term, the industry's ultimate safety goal. This paper relates to a four-loop pressurized water reactor

  12. The passive hamstring stretch test: clinical evaluation.

    Science.gov (United States)

    Fisk, J W

    1979-03-28

    The passive hamstring stretch test is described. Using a modified goniometer it is shown that independent measurements taken by trained examiners approximate very closely to each other. This establishes the test as a valid objective measurement. The possible value of this test as a research tool in low back pain problems is discussed.

  13. Passive containment system in high earthquake motion

    International Nuclear Information System (INIS)

    Kleimola, F.W.; Falls, O.B. Jr.

    1977-01-01

    High earthquake motion necessitates major design modifications in the complex of plant structures, systems and components in a nuclear power plant. Distinctive features imposed by seismic category, safety class and quality classification requirements for the high seismic ground acceleration loadings significantly reflect in plant costs. The design features in the Passive Containment System (PCS) responding to high earthquake ground motion are described

  14. Chances and barriers for passive house renovations

    NARCIS (Netherlands)

    Mlecnik, E.; Opstelten, I.; Rovers, R.; Verdeyen, N.; Wagenaar, A.

    2016-01-01

    There is significant potential for carbon reduction and energy saving in residential buildings. Various market actors are looking for ways to increase the uptake of passive house renovation and its certification.
    This study aimed specifically to draw lessons from research projects towards the

  15. Passive Polarimetric Microwave Signatures Observed Over Antarctica

    Science.gov (United States)

    WindSat satellite-based fully polarimetric passive microwave observations, expressed in the form of the Stokes vector, were analyzed over the Antarctic ice sheet. The vertically and horizontally polarized brightness temperatures (first two Stokes components) from WindSat are shown to be consistent w...

  16. Indoor environment in Swedish passive houses

    DEFF Research Database (Denmark)

    Bekö, Gabriel; Langer, Sarka; Bloom, Erica Bloom

    2014-01-01

    The purpose of this study was to evaluate the indoor air quality (IAQ) in newly built low energy houses. Measurements were performed in 22 passive houses and 21 conventional buildings during 2012-2013 and 2013-2014 heating seasons. The measured parameters were temperature, relative humidity......, concentration of CO2, NO2, formaldehyde, volatile organic compounds, and live microbiological flora. Air exchange rates (AER) were determined from the concentration-time profiles of CO2. The median AER was slightly higher in the passive houses than in conventional buildings (0.66 h-1 vs. 0.60 h-1). The median...... concentrations in passive houses and conventional buildings were 9.7 and 11 μg/m3, respectively, for NO2, 12 and 16 μg/m3 for formaldehyde, and 230 and 145 μg/m3 for TVOC. The indoor microbiological flora did not differ, with a few exceptions, from outdoors. The IAQ in the passive buildings was judged...

  17. Head Pose Estimation from Passive Stereo Images

    DEFF Research Database (Denmark)

    Breitenstein, Michael D.; Jensen, Jeppe; Høilund, Carsten

    2009-01-01

    function. Our algorithm incorporates 2D and 3D cues to make the system robust to low-quality range images acquired by passive stereo systems. It handles large pose variations (of ±90 ° yaw and ±45 ° pitch rotation) and facial variations due to expressions or accessories. For a maximally allowed error of 30...

  18. Radio requestable passive SAW water content sensor

    NARCIS (Netherlands)

    Reindl, L.; Ruppel, C.C.W.; Kirmayr, A.; Stockhausen, N.; Hilhorst, M.A.; Balendonk, J.

    2001-01-01

    A new passive sensor for remote measurement of water content in sandy soil was designed, using a surface acoustic wave (SAW) reflective delay line. Information from this sensor can be obtained by an interrogation device via a radio link operating in the European 434-MHz industrial-scientific-medical

  19. Active and Passive Microrheology: Theory and Simulation

    Science.gov (United States)

    Zia, Roseanna N.

    2018-01-01

    Microrheological study of complex fluids traces its roots to the work of the botanist Robert Brown in the early nineteenth century. Indeed, passive microrheology and Brownian motion are one and the same. Once thought to reveal a fundamental life force, the phenomenon was ultimately leveraged by Einstein in proof of the atomic nature of matter ( Haw 2006 ). His work simultaneously paved the way for modern-day passive microrheology by connecting observable particle motion—diffusion—to solvent properties—the viscosity—via the well-known Stokes-Einstein relation. Advances in microscopy techniques in the last two decades have prompted extensions of the original model to generalized forms for passive probing of complex fluids. In the last decade, active microrheology has emerged as a means by which to interrogate the nonequilibrium behavior of complex fluids, in particular, the non-Newtonian rheology of dynamically heterogeneous and microscopically small systems. Here we review theoretical and computational approaches and advances in both passive and active microrheology, with a focus on the extent to which these techniques preserve the connection between single-particle motion and flow properties, as well as the rather surprising recovery of non-Newtonian flow behavior observed in bulk rheology.

  20. Passive sampling methods for contaminated sediments

    DEFF Research Database (Denmark)

    Peijnenburg, Willie J.G.M.; Teasdale, Peter R.; Reible, Danny

    2014-01-01

    “Dissolved” concentrations of contaminants in sediment porewater (Cfree) provide a more relevant exposure metric for risk assessment than do total concentrations. Passive sampling methods (PSMs) for estimating Cfree offer the potential for cost-efficient and accurate in situ characterization...

  1. Optimization of Passive Coherent Receiver System Placement

    Science.gov (United States)

    2013-09-01

    spheroid object with a constant radar cross section (RCS). Additionally, the receiver and transmitters are assumed to be notional isotropic antennae...software- defined radio for equatorial plasma instability studies,” Radio Science, vol. 48, pp. 1–11. Aug. 2013. [2] P. C. Zhang and B. Y. Li, “Passive

  2. Development of passive radar systems at TNO

    NARCIS (Netherlands)

    Gelsema, S.J.

    2007-01-01

    Since 2002, the Netherlands Organisation for Applied Scientific Research – TNO, has been involved in the development of passive radar systems for research purposes. The development has been sponsored partly by the Royal Netherlands Air Force – whose main interest is threat evaluation – and partly by

  3. Passive Magnetic Latching Mechanisms For Robotic Applications

    KAUST Repository

    Fiaz, Usman

    2017-04-01

    This thesis investigates the passive magnetic latching mechanism designs for autonomous aerial grasping and programmable self-assembly. The enormous latching potential of neodymium magnets is a well-established fact when it comes to their ability to interact with ferrous surfaces in particular. The force of attraction or repulsion among the magnets is strong enough to keep the levitation trains, and high speed transportation pods off the rails. But such utilization of these desirable magnetic properties in commercial applications, comes at a cost of high power consumption since the magnets used are usually electromagnets. On the other hand, we explore some useful robotic applications of passive (and hence low cost) magnetic latching; which are of vital importance in autonomous aerial transportation, automated drone-based package deliveries, and programmable self-assembly and self-reconfigurable systems. We propose, and implement a novel, attach/detach mechatronic mechanism, based on passive magnetic latching of permanent magnets for usBots; our indige- nously built programmable self-assembly robots, and show that it validates the game theoretic self-assembly algorithms. Another application addressed in this thesis is the utilization of permanent magnets in autonomous aerial grasping for Unmanned Aerial Vehicles (UAVs). We present a novel gripper design for ferrous objects with a passive magnetic pick up and an impulse based drop. For both the applications, we highlight the importance, simplicity and effectiveness of the proposed designs while providing a brief comparison with the other technologies out there.

  4. Neutralization of wastewater from nitrite passivation

    International Nuclear Information System (INIS)

    Pawlowski, L.; Mientki, B.; Wasag, H.

    1982-01-01

    A method for neutralization of wastewater formed in nitrite passivation has been presented. The method consists of introducing urea into wastewater and acidifying it with sulphuric acid. Wastewater is neutralized with lime. After clarification, wastewater can be drained outside the plant

  5. Treat mine water using passive methods

    International Nuclear Information System (INIS)

    Kleinmann, R.L.P.; Hedin, R.S.

    1993-01-01

    Passive treatment represents an alternative to conventional chemical treatment of coal mine drainage. When successful, passive systems require less investment, less maintenance and usually are less expensive than conventional chemical treatment systems. As a result, during the last seven years, more than 500 passive systems have been constructed in the United States to treat coal mine drainage. Some exist as an alternative to conventional treatment; others serve as an inexpensive pretreatment step than can decrease subsequent chemical requirements. Sulfide minerals present in rock disturbed during mining can oxidize to form an acidic metal-laden solution, commonly known as acid mine drainage (AMD). Alkalinity present in the rock may partially or completely neutralize AMD, but if either acidity or excessive metal contaminants remain, the water must be treated before it can be discharged legally. The principal regulated contaminant metals of coal mine drainage are iron and manganese. Metal mine drainage often contains more toxic metals, such as cadmium, nickel, copper and zinc. Chemical treatment of AMD is estimated to cost America's mining industry more than $1 million a day. Three principal passive technologies are used in the treatment of coal mine drainage: Aerobic wetlands, wetlands constructed with an organic substrate and anoxic limestone drains (ALDS). The selection of the technology or combination of technologies to be used depends on the quality of the water being treated

  6. Passive prosthetic hands and tools: A literature review.

    Science.gov (United States)

    Maat, Bartjan; Smit, Gerwin; Plettenburg, Dick; Breedveld, Paul

    2018-02-01

    The group of passive prostheses consists of prosthetic hands and prosthetic tools. These can either be static or adjustable. Limited research and development on passive prostheses has been performed although many people use these prosthesis types. Although some publications describe passive prostheses, no recent review of the peer-reviewed literature on passive prostheses is available. Review the peer-reviewed literature on passive prostheses for replacement of the hand. Literature review. Four electronic databases were searched using a Boolean combination of relevant keywords. English-language articles relevant to the objective were selected. In all, 38 papers were included in the review. Publications on passive prosthetic hands describe their users, usage, functionality, and problems in activities of daily living. Publications on prosthetic tools mostly focus on sport, recreation, and vehicle driving. Passive hand prostheses receive little attention in prosthetic research and literature. Yet one out of three people with a limb deficiency uses this type of prosthesis. Literature indicates that passive prostheses can be improved on pulling and grasping functions. In the literature, ambiguous names are used for different types of passive prostheses. This causes confusion. We present a new and clear classification of passive prostheses. Clinical relevance This review provides information on the users of passive prosthetic hands and tools, their usage and the functionality. Passive prostheses receive very little attention and low appreciation in literature. Passive prosthetic hands and tools show to be useful to many unilateral amputees and should receive more attention and higher acceptance.

  7. La syphilis congenitale revelee par une fracture spontanee

    Directory of Open Access Journals (Sweden)

    Mounia Lakhdar Idrissi

    2011-11-01

    Full Text Available Alors qu�elle est actuellement oubliee dans les pays developpes, la syphilis congenitale se voit encore chez nous faute du depistage antenatal. Ses formes cliniques sont polymorphes et orientent a tord vers d�autres pathologies surtout en periode neonatale. Le diagnostic n�est donc pas toujours facile. La revelation d�une syphilis congenitale par une fracture spontanee est exceptionnellement decrite. Nous rapportons dans ce travail le cas d�un nourrisson de 2 mois ramene en consultation pour limitation douloureuse des mouvements du bras droit. Le diagnostic est evoque sur les donnees radiologiques et confirme par la serologie syphilitique. Le traitement a repose essentiellement sur l�administration de la penicilline G avec une bonne evolution clinique.

  8. Results of Preliminary Tests of PAR Bunch Cleaning

    CERN Document Server

    Yao, Chihyuan; Grelick, Arthur; Lumpkin, Alex H; Sereno, Nicholas S

    2005-01-01

    A particle accumulator ring (PAR) is used at the Advanced Photon Source (APS) to collect multiple linac bunches and compress them into a 0.3-ns (rms) single bunch for booster injection. A 9.77-MHz fundamental rf system and a 117.3-MHz harmonic rf system are employed for initial beam capture and bunch length compression. Satellite bunches with very low charge form due to rf phase drifts or beam loading change. These satellites, when injected into the booster and then into the storage ring (SR), cause bunch impurity at three buckets from the target bucket. Storage ring and booster bunch cleaning was tried but proved to be difficult due to the top-up mode of operation in the storage ring and tune drift in the booster synchrotron. Recently we implemented a PAR bunch-cleaning system with tune-modulated harmonic rf knockout. Preliminary tests gave a measured SR bunch purity of better than 10

  9. Avis 6 sur la formation à et par la recherche

    OpenAIRE

    Centre de Coopération Internationale en Recherche Agronomique pour le Développement

    2015-01-01

    La formation à et par la recherche s’appuie sur la démarche scientifique, les savoirs, les connaissances à transmettre, tout autant que l’acquisition de compétences en gestion de projet, de capacités au travail en équipe, d’une ouverture d’esprit qui favorisera la créativité. Elle doit permettre de prendre conscience de la responsabilité endossée par la communauté scientifique vis-à-vis de la société et de l’environnement, mais aussi préparer l’avenir professionnel de celle ou de celui qu...

  10. Evaluation of the Stability After Orthodontic Treatment Using PAR Index

    Directory of Open Access Journals (Sweden)

    Chaitra Ramanathan

    2006-01-01

    Full Text Available The aim of the present study is to establish the results using the scores obtained from the methodology that was applied for assessing the stability after 2 years post orthodontic treatment and stability in a sample of 69 individuals. After applying PAR index to the collected group of patients, a series of scores were obtained, which were then needed to be evaluated further to establish the results. The scores were evaluated using the nomogram. A comparison was done between the post treatment and the 2 years post treatment PAR weighting scores to determine if the results were stable after orthodontic treatment. The majority of the orthodontic patients were treated to a good standard and that the results appeared to be stable.

  11. La parálisis cerebral en el contexto escolar /

    OpenAIRE

    González Vara, Azucena

    2012-01-01

    Se analiza el concepto de parálisis cerebral, los diferentes tipos y sus características. También las adaptaciones que se deben realizar a nivel de centro, de aula, y a nivel individual para estos alumnos, conocer los diferentes sistemas alternativos y aumentativos de comunicación y aplicar las ayudas técnicas que precisa este alumnado

  12. Tuberculose lymphonodale cervicale chez les enfants vaccines par ...

    African Journals Online (AJOL)

    La tuberculose ganglionnaire cervicale est une localisation extrapulmonaire relativement fréquente chez l'enfant. Elle pose essentiellement des difficultés de prévention. L'objectif de ce travail est d'étudier les particularités diagnostiques et thérapeutiques chez des enfants vaccinés par le BCG. Matériel et méthodes: Nôtre ...

  13. Traitement De La Peripneumonie Contagieuse Bovine Par L ...

    African Journals Online (AJOL)

    Traitement De La Peripneumonie Contagieuse Bovine Par L'oxyteTracycline Longe Action Et Transmission Experimentale de la Maladie A Partir de Bovins Traites. ... Tous les 14 animaux ont séroconverti et l'analyse post-mortem a montré la présence des lésions chroniques dont des séquestres pulmonaires chez 4 d'entre ...

  14. Adoption d'innovations agricoles par le truchement de services ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    L'agriculture est le fer de lance de nombreuses économies en développement, mais la capacité des petits agriculteurs privés de ressources à adopter des innovations agricoles est freinée par le manque d'accès à des services financiers adéquats. Des experts internationaux estiment qu'il existe un manque à gagner ...

  15. Candido: Uma Leitura Paródica de Candide

    Directory of Open Access Journals (Sweden)

    Maria Gloria Cusumano Mazzi

    2010-12-01

    Full Text Available O presente artigo estuda a leitura paródica que Leonardo Sciascia (1921-1989 faz de Voltaire (1694-1778 mediante o cotejo das obras: o hipertexto Candido ovvero Un sogno fatto in Sicilia (1977 e o hipotexto Candide ou l’optimisme (1759. Apresenta ainda outra possibilidade de leitura, ou seja, Candido como metáfora da própria intertextualidade.

  16. Solution volumes finis polynomiale par morceaux pour les ...

    African Journals Online (AJOL)

    Nous présentons dans ce papier un concept de solution volumes finis continue pour des problèmes de diffusion-convection avec des données régulières. Nous comparons dans certains cas particuliers la solution proposée avec la solution volumes finis classiques (qui est une fonction constante par morceaux) et la ...

  17. Hybrid passivated colloidal quantum dot solids

    KAUST Repository

    Ip, Alex

    2012-07-29

    Colloidal quantum dot (CQD) films allow large-area solution processing and bandgap tuning through the quantum size effect. However, the high ratio of surface area to volume makes CQD films prone to high trap state densities if surfaces are imperfectly passivated, promoting recombination of charge carriers that is detrimental to device performance. Recent advances have replaced the long insulating ligands that enable colloidal stability following synthesis with shorter organic linkers or halide anions, leading to improved passivation and higher packing densities. Although this substitution has been performed using solid-state ligand exchange, a solution-based approach is preferable because it enables increased control over the balance of charges on the surface of the quantum dot, which is essential for eliminating midgap trap states. Furthermore, the solution-based approach leverages recent progress in metal:chalcogen chemistry in the liquid phase. Here, we quantify the density of midgap trap states in CQD solids and show that the performance of CQD-based photovoltaics is now limited by electrong-"hole recombination due to these states. Next, using density functional theory and optoelectronic device modelling, we show that to improve this performance it is essential to bind a suitable ligand to each potential trap site on the surface of the quantum dot. We then develop a robust hybrid passivation scheme that involves introducing halide anions during the end stages of the synthesis process, which can passivate trap sites that are inaccessible to much larger organic ligands. An organic crosslinking strategy is then used to form the film. Finally, we use our hybrid passivated CQD solid to fabricate a solar cell with a certified efficiency of 7.0%, which is a record for a CQD photovoltaic device. © 2012 Macmillan Publishers Limited. All rights reserved.

  18. Hybrid passivated colloidal quantum dot solids

    KAUST Repository

    Ip, Alex; Thon, Susanna; Hoogland, Sjoerd H.; Voznyy, Oleksandr; Zhitomirsky, David; Debnath, Ratan K.; Levina, Larissa; Rollny, Lisa R.; Carey, Graham H.; Fischer, Armin H.; Kemp, Kyle W.; Kramer, Illan J.; Ning, Zhijun; Labelle, André J.; Chou, Kang Wei; Amassian, Aram; Sargent, E. H.

    2012-01-01

    Colloidal quantum dot (CQD) films allow large-area solution processing and bandgap tuning through the quantum size effect. However, the high ratio of surface area to volume makes CQD films prone to high trap state densities if surfaces are imperfectly passivated, promoting recombination of charge carriers that is detrimental to device performance. Recent advances have replaced the long insulating ligands that enable colloidal stability following synthesis with shorter organic linkers or halide anions, leading to improved passivation and higher packing densities. Although this substitution has been performed using solid-state ligand exchange, a solution-based approach is preferable because it enables increased control over the balance of charges on the surface of the quantum dot, which is essential for eliminating midgap trap states. Furthermore, the solution-based approach leverages recent progress in metal:chalcogen chemistry in the liquid phase. Here, we quantify the density of midgap trap states in CQD solids and show that the performance of CQD-based photovoltaics is now limited by electrong-"hole recombination due to these states. Next, using density functional theory and optoelectronic device modelling, we show that to improve this performance it is essential to bind a suitable ligand to each potential trap site on the surface of the quantum dot. We then develop a robust hybrid passivation scheme that involves introducing halide anions during the end stages of the synthesis process, which can passivate trap sites that are inaccessible to much larger organic ligands. An organic crosslinking strategy is then used to form the film. Finally, we use our hybrid passivated CQD solid to fabricate a solar cell with a certified efficiency of 7.0%, which is a record for a CQD photovoltaic device. © 2012 Macmillan Publishers Limited. All rights reserved.

  19. Preliminary Analysis For Wolsong Par Effects Using ISACC Calculations

    International Nuclear Information System (INIS)

    Song, Yong Mann; Kim, Dong Ha

    2012-01-01

    In the paper, hydrogen control effects using PARs only are analyzed for severe SBO station blackout (SBO) sequences beyond the design basis accidents in WS-1 which are of CANDU6 type reactor. As a computational tool, the latest version of ISAAC4.3 (Integrated Severe Accident Analysis Code for CANDU), which is a fully integrated and lumped severe accident computer code, is used to simulate hydrogen generation and transport inside the reactor building (R/B) before its failure. For the performance of hydrogen removal, the depletion rate equation of K-PAR developed in Korea is applied. In a CANDU reactor, three areas are identified as sources of hydrogen under severe accidents: fuel-coolant interactions in intact channels, suspended fuel or debris interactions in-calandria tank and debris interactions in-calandria vault. The first two origins provide source for the late ('late' terminology is used because it takes more than one day before calandria tank failure) potential hydrogen combustion before calandria tank failure and all the three origins would provide source for the very late potential hydrogen combustion occurring at or after calaria tank failure. If the hydrogen mitigation system fails, the AICC (adiabatic isochoric complete combustion) burning of highly flammable hydrogen may cause Wolsong R/B failure. So hydrogen induced failure possibility is evaluated, using preliminary ISAAC calculations, under several SBO conditions with and without PAR for both late and very late accident periods

  20. Protease activated receptors (PARS) mediation in gyroxin biological activity

    International Nuclear Information System (INIS)

    Silva, Jose Alberto Alves da

    2009-01-01

    Gyroxin is a serine protease enzyme from the South American rattlesnake (Crotalus durissus terrificus) venom; it is only partially characterized and has multiple activities. Gyroxin induces blood coagulation, blood pressure decrease and a neurotoxic behavior named barrel rotation. The mechanisms involved in this neurotoxic activity are not known. Whereas gyroxin is a member of enzymes with high potential to become a new drug with clinical applications such as thrombin, batroxobin, ancrod, tripsyn and kalicrein, it is important to find out how gyroxin works. The analysis on agarose gel electrophoresis and circular dichroism confirmed the molecules' integrity and purity. The gyroxin intravenous administration in mice proved its neurotoxicity (barrel rotation). In vivo studies employing intravital microscopy proved that gyroxin induces vasodilation with the participation of protease activated receptors (PARs), nitric oxide and Na+K+ATPase. The leukocytes' adherence and rolling counting indicated that gyroxin has no pro inflammatory activity. Gyroxin induced platelet aggregation, which was blocked by inhibitors of PAR1 and PAR4 receptors (SCH 79797 and tcY-NH 2 , respectively). Finally, it was proved that the gyroxin temporarily alter the permeability of the blood brain barrier (BBB). Our study has shown that both the protease-activated receptors and nitric oxide are mediators involved in the biological activities of gyroxin. (author)

  1. Design of integrated passive safety system (IPSS) for ultimate passive safety of nuclear power plants

    International Nuclear Information System (INIS)

    Chang, Soon Heung; Kim, Sang Ho; Choi, Jae Young

    2013-01-01

    Highlights: • We newly propose the design concept of integrated passive safety system (IPSS). • It has five safety functions for decay heat removal and severe accident mitigation. • Simulations for IPSS show that core melt does not occur in accidents with SBO. • IPSS can achieve the passive in-vessel retention and ex-vessel cooling strategy. • The applicability of IPSS is high due to the installation outside the containment. -- Abstract: The design concept of integrated passive safety system (IPSS) which can perform various passive safety functions is proposed in this paper. It has the various functions of passive decay heat removal system, passive safety injection system, passive containment cooling system, passive in-vessel retention and cavity flooding system, and filtered venting system with containment pressure control. The objectives of this paper are to propose the conceptual design of an IPSS and to estimate the design characters of the IPSS with accident simulations using MARS code. Some functions of the IPSS are newly proposed and the other functions are reviewed with the integration of the functions. Consequently, all of the functions are modified and integrated for simplicity of the design in preparation for beyond design based accidents (BDBAs) focused on a station black out (SBO). The simulation results with the IPSS show that the decay heat can be sufficiently removed in accidents that occur with a SBO. Also, the molten core can be retained in a vessel via the passive in-vessel retention strategy of the IPSS. The actual application potential of the IPSS is high, as numerous strong design characters are evaluated. The installation of the IPSS into the original design of a nuclear power plant requires minimal design change using the current penetrations of the containment. The functions are integrated in one or two large tanks outside the containment. Furthermore, the operation time of the IPSS can be increased by refilling coolant from the

  2. A Bipolar Spindle of Antiparallel ParM Filaments Drives Bacterial Plasmid Segregation

    DEFF Research Database (Denmark)

    Gayathri, P; Fujii, T; Møller-Jensen, Jakob

    2012-01-01

    the spindle between ParRC complexes on sister plasmids. Using a combination of structural work and total internal reflection fluorescence microscopy, we show that ParRC bound and could accelerate growth at only one end of polar ParM filaments, mechanistically resembling eukaryotic formins. The architecture...... of ParM filaments enabled two ParRC-bound filaments to associate in an antiparallel orientation, forming a bipolar spindle. The spindle elongated as a bundle of at least two antiparallel filaments, thereby pushing two plasmid clusters toward the poles....

  3. First (18)F-labeled ligand for PET imaging of uPAR

    DEFF Research Database (Denmark)

    Persson, Morten; Liu, Hongguang; Madsen, Jacob

    2013-01-01

    Urokinase-type plasminogen activator receptor (uPAR) is overexpressed in human prostate cancer and uPAR has been found to be associated with metastatic disease and poor prognosis. AE105 is a small linear peptide with high binding affinity to uPAR. We synthesized an N-terminal NOTA......-conjugated version (NOTA-AE105) for development of the first (18)F-labeled uPAR positron-emission-tomography PET ligand using the Al(18)F radiolabeling method. In this study, the potential of (18)F-AlF-NOTA-AE105 to specifically target uPAR-positive prostate tumors was investigated....

  4. Intact and cleaved uPAR forms: diagnostic and prognostic value in cancer

    DEFF Research Database (Denmark)

    Rasch, M.G.; Lund, I.K.; Hoyer-Hansen, G.

    2008-01-01

    identified in tissue and body fluids. It is well-established, that the total amount of all uPAR forms is a strong prognostic marker in different types of cancer. Using immunoassays, measuring the individual uPAR forms, has revealed that the cleaved uPAR forms are even stronger prognostic markers and have...... diagnostic utility. This review will focus on the mechanism of uPAR cleavage and the functional consequences, as well as the clinical applicability of cleaved uPAR forms Udgivelsesdato: 2008...

  5. Surface passivation process of compound semiconductor material using UV photosulfidation

    Science.gov (United States)

    Ashby, Carol I. H.

    1995-01-01

    A method for passivating compound semiconductor surfaces by photolytically disrupting molecular sulfur vapor with ultraviolet radiation to form reactive sulfur which then reacts with and passivates the surface of compound semiconductors.

  6. L2-gain and passivity techniques in nonlinear control

    CERN Document Server

    van der Schaft, Arjan

    2017-01-01

    This standard text gives a unified treatment of passivity and L2-gain theory for nonlinear state space systems, preceded by a compact treatment of classical passivity and small-gain theorems for nonlinear input-output maps. The synthesis between passivity and L2-gain theory is provided by the theory of dissipative systems. Specifically, the small-gain and passivity theorems and their implications for nonlinear stability and stabilization are discussed from this standpoint. The connection between L2-gain and passivity via scattering is detailed. Feedback equivalence to a passive system and resulting stabilization strategies are discussed. The passivity concepts are enriched by a generalised Hamiltonian formalism, emphasising the close relations with physical modeling and control by interconnection, and leading to novel control methodologies going beyond passivity. The potential of L2-gain techniques in nonlinear control, including a theory of all-pass factorizations of nonlinear systems, and of parametrization...

  7. Study on diverse passive decay heat removal approach and principle

    International Nuclear Information System (INIS)

    Lin Qian; Si Shengyi

    2012-01-01

    Decay heat removal in post-accident is one of the most important aspects concerned in the reactor safety analysis. Passive decay heat removal approach is used to enhance nuclear safety. In advanced reactors, decay heat is removed by multiple passive heat removal paths through core to ultimate heat sink by passive residual heat removal system, passive injection system, passive containment cooling system and so on. Various passive decay heat removal approaches are summarized in this paper, the common features and differences of their heat removal paths are analyzed, and the design principle of passive systems for decay heat removal is discussed. It is found that. these decay heat removal paths is combined by some basic heat transfer processes, by the combination of these basic processes, diverse passive decay heat removal approach or system design scheme can be drawn. (authors)

  8. Nanolayer surface passivation schemes for silicon solar cells

    NARCIS (Netherlands)

    Dingemans, G.

    2011-01-01

    This thesis is concerned with nanolayer surface passivation schemes and corresponding deposition processes, for envisaged applications in crystalline silicon solar cells. Surface passivation, i.e. the reduction of electronic recombination processes at semiconductor surfaces, is essential for

  9. Dynamic Filament Formation by a Divergent Bacterial Actin-Like ParM Protein.

    Directory of Open Access Journals (Sweden)

    Anthony J Brzoska

    Full Text Available Actin-like proteins (Alps are a diverse family of proteins whose genes are abundant in the chromosomes and mobile genetic elements of many bacteria. The low-copy-number staphylococcal multiresistance plasmid pSK41 encodes ParM, an Alp involved in efficient plasmid partitioning. pSK41 ParM has previously been shown to form filaments in vitro that are structurally dissimilar to those formed by other bacterial Alps. The mechanistic implications of these differences are not known. In order to gain insights into the properties and behavior of the pSK41 ParM Alp in vivo, we reconstituted the parMRC system in the ectopic rod-shaped host, E. coli, which is larger and more genetically amenable than the native host, Staphylococcus aureus. Fluorescence microscopy showed a functional fusion protein, ParM-YFP, formed straight filaments in vivo when expressed in isolation. Strikingly, however, in the presence of ParR and parC, ParM-YFP adopted a dramatically different structure, instead forming axial curved filaments. Time-lapse imaging and selective photobleaching experiments revealed that, in the presence of all components of the parMRC system, ParM-YFP filaments were dynamic in nature. Finally, molecular dissection of the parMRC operon revealed that all components of the system are essential for the generation of dynamic filaments.

  10. Proteinase-Activated Receptor 1 (PAR1 regulates leukemic stem cell functions.

    Directory of Open Access Journals (Sweden)

    Nicole Bäumer

    Full Text Available External signals that are mediated by specific receptors determine stem cell fate. The thrombin receptor PAR1 plays an important role in haemostasis, thrombosis and vascular biology, but also in tumor biology and angiogenesis. Its expression and function in hematopoietic stem cells is largely unknown. Here, we analyzed expression and function of PAR1 in primary hematopoietic cells and their leukemic counterparts. AML patients' blast cells expressed much lower levels of PAR1 mRNA and protein than CD34+ progenitor cells. Constitutive Par1-deficiency in adult mice did not affect engraftment or stem cell potential of hematopoietic cells. To model an AML with Par1-deficiency, we retrovirally introduced the oncogene MLL-AF9 in wild type and Par1-/- hematopoietic progenitor cells. Par1-deficiency did not alter initial leukemia development. However, the loss of Par1 enhanced leukemic stem cell function in vitro and in vivo. Re-expression of PAR1 in Par1-/- leukemic stem cells delayed leukemogenesis in vivo. These data indicate that Par1 contributes to leukemic stem cell maintenance.

  11. Proteinase-Activated Receptor 1 (PAR1) regulates leukemic stem cell functions.

    Science.gov (United States)

    Bäumer, Nicole; Krause, Annika; Köhler, Gabriele; Lettermann, Stephanie; Evers, Georg; Hascher, Antje; Bäumer, Sebastian; Berdel, Wolfgang E; Müller-Tidow, Carsten; Tickenbrock, Lara

    2014-01-01

    External signals that are mediated by specific receptors determine stem cell fate. The thrombin receptor PAR1 plays an important role in haemostasis, thrombosis and vascular biology, but also in tumor biology and angiogenesis. Its expression and function in hematopoietic stem cells is largely unknown. Here, we analyzed expression and function of PAR1 in primary hematopoietic cells and their leukemic counterparts. AML patients' blast cells expressed much lower levels of PAR1 mRNA and protein than CD34+ progenitor cells. Constitutive Par1-deficiency in adult mice did not affect engraftment or stem cell potential of hematopoietic cells. To model an AML with Par1-deficiency, we retrovirally introduced the oncogene MLL-AF9 in wild type and Par1-/- hematopoietic progenitor cells. Par1-deficiency did not alter initial leukemia development. However, the loss of Par1 enhanced leukemic stem cell function in vitro and in vivo. Re-expression of PAR1 in Par1-/- leukemic stem cells delayed leukemogenesis in vivo. These data indicate that Par1 contributes to leukemic stem cell maintenance.

  12. Fusion reactor passive safety and ignitor risk-based regulation

    International Nuclear Information System (INIS)

    Zucchetti, M.

    1995-01-01

    Passive design features are more reliable than operator action of successful operation of active safety systems. Passive safety has usually been adopted for fission. The achievement of an inventory-based passive safety is difficult if the fusion reactor uses neutronic reactions. Ignitor is a high-magnetic field tokamak designed to study the physics of ignited plasmas. The safety goal for Ignitor is classification as a mobility-based passively safe machine

  13. 17 CFR 242.103 - Nasdaq passive market making.

    Science.gov (United States)

    2010-04-01

    ... paragraph (b)(2) of this section. (4) Limitation on displayed size. At all times, the passive market maker's... may display a bid size of 100 shares. (5) Identification of a passive market making bid. The bid... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Nasdaq passive market making...

  14. South African passive radar and towards its characterisation

    CSIR Research Space (South Africa)

    Lysko, Albert A

    2017-05-01

    Full Text Available A passive or passive coherent location (PCL) radar does not have an own transmitter or require owning spectrum, making it a very cost effective instrument for tracking non-cooperative targets. The paper discusses achievements in FM-based passive...

  15. The double par locus of virulence factor pB171: DNA segregation is correlated with oscillation of ParA

    DEFF Research Database (Denmark)

    Ebersbach, G; Gerdes, K; Charbon, Gitte Ebersbach

    2001-01-01

    Prokaryotic plasmids and chromosomes encode partitioning (par) loci that segregate DNA to daughter cells before cell division. Recent database analyses showed that almost all known par loci encode an ATPase and a DNA-binding protein, and one or more cis-acting regions where the proteins act. All...

  16. Citric Acid Alternative to Nitric Acid Passivation

    Science.gov (United States)

    Lewis, Pattie L. (Compiler)

    2013-01-01

    The Ground Systems Development and Operations GSDO) Program at NASA John F. Kennedy Space Center (KSC) has the primary objective of modernizing and transforming the launch and range complex at KSC to benefit current and future NASA programs along with other emerging users. Described as the launch support and infrastructure modernization program in the NASA Authorization Act of 2010, the GSDO Program will develop and implement shared infrastructure and process improvements to provide more flexible, affordable, and responsive capabilities to a multi-user community. In support of the GSDO Program, the purpose of this project is to demonstratevalidate citric acid as a passivation agent for stainless steel. Successful completion of this project will result in citric acid being qualified for use as an environmentally preferable alternative to nitric acid for passivation of stainless steel alloys in NASA and DoD applications.

  17. Passive appendages generate drift through symmetry breaking

    Science.gov (United States)

    Lācis, U.; Brosse, N.; Ingremeau, F.; Mazzino, A.; Lundell, F.; Kellay, H.; Bagheri, S.

    2014-10-01

    Plants and animals use plumes, barbs, tails, feathers, hairs and fins to aid locomotion. Many of these appendages are not actively controlled, instead they have to interact passively with the surrounding fluid to generate motion. Here, we use theory, experiments and numerical simulations to show that an object with a protrusion in a separated flow drifts sideways by exploiting a symmetry-breaking instability similar to the instability of an inverted pendulum. Our model explains why the straight position of an appendage in a fluid flow is unstable and how it stabilizes either to the left or right of the incoming flow direction. It is plausible that organisms with appendages in a separated flow use this newly discovered mechanism for locomotion; examples include the drift of plumed seeds without wind and the passive reorientation of motile animals.

  18. Passive appendages aid locomotion through symmetry breaking

    Science.gov (United States)

    Bagheri, Shervin; Lacis, Ugis; Mazzino, Andrea; Kellay, Hamid; Brosse, Nicolas; Lundell, Fredrik; Ingremeau, Francois

    2014-11-01

    Plants and animals use plumes, barbs, tails, feathers, hairs, fins, and other types of appendages to aid locomotion. Despite their enormous variation, passive appendages may contribute to locomotion by exploiting the same physical mechanism. We present a new mechanism that applies to body appendages surrounded by a separated flow, which often develops behind moving bodies larger than a few millimeters. We use theory, experiments, and numerical simulations to show that bodies with protrusions turn and drift by exploiting a symmetry-breaking instability similar to the instability of an inverted pendulum. Our model explains why the straight position of an appendage in flowing fluid is unstable and how it stabilizes either to the left or right of the incoming fluid flow direction. The discovery suggests a new mechanism of locomotion that may be relevant for certain organisms; for example, how plumed seeds may drift without wind and how motile animals may passively reorient themselves.

  19. A passive solar heater-refrigerator

    International Nuclear Information System (INIS)

    D'Isep, F.; Sertorio, L.

    1983-01-01

    In this paper it is studied the nonequilibrium thermodynamic steady-state behaviour of a model system representing a core surrounded by an envelope in which the envelope interacts with the solar radiation and with an external bath having a given temperature profile. The heat flow between core and envelope can be controlled by varying the thermal conductivity of their interface. It is shown that this system acts as a passive heat pump raising the core average temperature with respect to the average equilibrium value corresponding to a fixed value of the interface conductivity, at the same time flattening its oscillation in time. By changing the time dependence of the conductivity the system vice versa acts as a refrigerator. It is shown how the limits of this performance depend on the passive parameters such as surfaces, conductivities, heat capacities. The periodicity considered in this study is the daily cycle

  20. Comparison of active and passive stream restoration

    DEFF Research Database (Denmark)

    Kristensen, Esben Astrup; Thodsen, Hans; Dehli, Bjarke

    2013-01-01

    Modification and channelization of streams and rivers have been conducted extensively throughout the world during the past century. Subsequently, much effort has been directed at re-creating the lost habitats and thereby improving living conditions for aquatic organisms. However, as restoration...... methods are plentiful, it is difficult to determine which one to use to get the anticipated result. The aim of this study was to compare two commonly used methods in small Danish streams to improve the physical condition: re-meandering and passive restoration through cease of maintenance. Our...... investigation included measurement of the physical conditions in 29 stream reaches covering four different groups: (1) re-meandered streams, (2) LDC streams (the least disturbed streams available), (3) passively restored streams (>10 years stop of aintenance) and (4) channelized and non-restored streams. The in...

  1. Secure passive RFID tag with seal

    Science.gov (United States)

    Nekoogar, Faranak; Reynolds, Matthew; Lefton, Scott; Dowla, Farid; Twogood, Richard

    2017-11-14

    A secure passive RFID tag system comprises at least one base station and at least one passive RFID tag. The tag includes a fiber optic cable with the cable ends sealed within the tag and the middle portion forming an external loop. The loop may be secured to at least portions of an object. The tag transmits and receives an optical signal through the fiber optic cable, and the cable is configured to be damaged or broken in response to removal or tampering attempts, wherein the optical signal is significantly altered if the cable is damaged or broken. The tag transmits the optical signal in response to receiving a radio signal from the base station and compares the transmitted optical signal to the received optical signal. If the transmitted optical signal and the received optical signal are identical, the tag transmits an affirmative radio signal to the base station.

  2. Passive cooling of control rod drive mechanisms

    International Nuclear Information System (INIS)

    Hankinson, M.F.; Schwirian, R.E.

    1992-01-01

    A method and apparatus are provided for passively cooling the control rod drive mechanisms (CRDMs) in the reactor vessel of a nuclear power plant. Passive cooling is achieved by dispersing a plurality of chimneys within the CRDM array in positions where a control rod is not required. The chimneys induce convective air currents which cause ambient air from within the containment to flow over the CRDM coils. The air heated by the coils is guided into inlets in the chimneys by baffles. The chimney is insulated and extends through the seismic support platform and missile shield disposed above the closure head. A collar of adjustable height mates with plate elements formed at the distal end of the CRDM pressure housings by an interlocking arrangement so that the seismic support platform provides lateral restraint for the chimneys. (Author)

  3. Solar passive buildings for developing countries

    International Nuclear Information System (INIS)

    Gupta, C.L.

    1993-01-01

    This paper is meant to be an indicative survey of developments in solar passive building technology relevant to developing countries. The evolution of this area during the last fifty years is reported along with the scientific principles and design concepts underlying these developments. Factors to be considered for design strategies such as direct gain, isolated gain, indirect gain and roof evaporative systems are then described. Rating parameters for assessing the performance and benefit and cost parameters are then outlined. Successful examples illustrating each of the design concepts, mainly from Indian buildings constructed during the last fifteen years, are then detailed along with their performance based on actual monitoring, if available. Concluding remarks indicate the current and future trends. A survey is made of papers marking significant milestones in the development of solar passive building technology relevant to developing countries. (author). 48 refs., 14 figs., 3 tabs

  4. Active and passive vibration control of structures

    CERN Document Server

    Spelsberg-Korspeter, Gottfried

    2014-01-01

    Active and Passive Vibration Control of Structures form an issue of very actual interest in many different fields of engineering, for example in the automotive and aerospace industry, in precision engineering (e.g. in large telescopes), and also in civil engineering. The papers in this volume bring together engineers of different background, and it fill gaps between structural mechanics, vibrations and modern control theory.  Also links between the different applications in structural control are shown.

  5. Pulsed Laser Deposition: passive and active waveguides

    Czech Academy of Sciences Publication Activity Database

    Jelínek, Miroslav; Flory, F.; Escoubas, L.

    2009-01-01

    Roč. 34, č. 4 (2009), s. 438-449 ISSN 0268-1900 R&D Projects: GA ČR GA202/06/0216 Institutional research plan: CEZ:AV0Z10100522 Keywords : PLD * pulsed laser deposition * laser ablation * passive waveguides * active waveguides * waveguide laser * sensors * thin films * butane detection Subject RIV: BH - Optics, Masers, Lasers Impact factor: 0.384, year: 2009

  6. Surface passivation for CdTe devices

    Energy Technology Data Exchange (ETDEWEB)

    Reese, Matthew O.; Perkins, Craig L.; Burst, James M.; Gessert, Timothy A.; Barnes, Teresa M.; Metzger, Wyatt K.

    2017-08-01

    In one embodiment, a method for surface passivation for CdTe devices is provided. The method includes adjusting a stoichiometry of a surface of a CdTe material layer such that the surface becomes at least one of stoichiometric or Cd-rich; and reconstructing a crystalline lattice at the surface of the CdTe material layer by annealing the adjusted surface.

  7. Passive microwave remote sensing of soil moisture

    International Nuclear Information System (INIS)

    Jackson, T.J.; Schmugge, T.J.

    1986-01-01

    Microwave remote sensing provides a unique capability for direct observation of soil moisture. Remote measurements from space afford the possibility of obtaining frequent, global sampling of soil moisture over a large fraction of the Earth's land surface. Microwave measurements have the benefit of being largely unaffected by cloud cover and variable surface solar illumination, but accurate soil moisture estimates are limited to regions that have either bare soil or low to moderate amounts of vegetation cover. A particular advantage of passive microwave sensors is that in the absence of significant vegetation cover soil moisture is the dominant effect on the received signal. The spatial resolutions of passive microwave soil moisture sensors currently considered for space operation are in the range 10–20 km. The most useful frequency range for soil moisture sensing is 1–5 GHz. System design considerations include optimum choice of frequencies, polarizations, and scanning configurations, based on trade-offs between requirements for high vegetation penetration capability, freedom from electromagnetic interference, manageable antenna size and complexity, and the requirement that a sufficient number of information channels be available to correct for perturbing geophysical effects. This paper outlines the basic principles of the passive microwave technique for soil moisture sensing, and reviews briefly the status of current retrieval methods. Particularly promising are methods for optimally assimilating passive microwave data into hydrologic models. Further studies are needed to investigate the effects on microwave observations of within-footprint spatial heterogeneity of vegetation cover and subsurface soil characteristics, and to assess the limitations imposed by heterogeneity on the retrievability of large-scale soil moisture information from remote observations

  8. Characterization of tetraethylene glycol passivated iron nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Nunes, Eloiza da Silva; Viali, Wesley Renato [Laboratório de Materiais Magnéticos e Coloides, Departamento de Físico-química, Instituto de Química, Universidade Estadual Paulista, Araraquara, SP 14801-970 (Brazil); Silva, Sebastião William da; Coaquira, José Antonio Huamaní; Garg, Vijayendra Kumar; Oliveira, Aderbal Carlos de [Instituto de Física, Núcleo de Física Aplicada, Universidade de Brasília, Brasília, DF 70910-900 (Brazil); Morais, Paulo César [Instituto de Física, Núcleo de Física Aplicada, Universidade de Brasília, Brasília, DF 70910-900 (Brazil); School of Automation, Huazhong University of Science and Technology, Wuhan 430074 (China); Jafelicci Júnior, Miguel, E-mail: jafeli@iq.unesp.br [Laboratório de Materiais Magnéticos e Coloides, Departamento de Físico-química, Instituto de Química, Universidade Estadual Paulista, Araraquara, SP 14801-970 (Brazil)

    2014-10-01

    Graphical abstract: - Highlights: • Metallic iron nanoparticles were passivated in tetraethylene glycol media. • Passivated nanoparticles presented pomegranate-like core@shell structure. • Passivation of metallic iron correlates with the tetraethylene glycol degradation. • Boron enriched metallic iron phase was more susceptible to oxidation. • The iron oxide shell was identified as Fe{sub 3}O{sub 4} with a mass fraction of 43:53 related to αFe. - Abstract: The present study describes the synthesis and characterization of iron@iron oxide nanoparticles produced by passivation of metallic iron in tetraethylene glycol media. Structural and chemical characterizations were performed using transmission electron microscopy (TEM), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), and Mössbauer spectroscopy. Pomegranate-like core@shell nanoparticulate material in the size range of 90–120 nm was obtained. According to quantitative phase analysis using Rietveld structure refinement the synthesized iron oxide was identified as magnetite (Fe{sub 3}O{sub 4}) whereas the iron to magnetite mass fractions was found to be 47:53. These findings are in good agreement with the data obtained from Mössbauer and thermal gravimetric analysis (TGA). The XPS data revealed the presence of a surface organic layer with higher hydrocarbon content, possibly due to the tetraethylene glycol thermal degradation correlated with iron oxidation. The room-temperature (300 K) saturation magnetization measured for the as-synthesized iron and for the iron–iron oxide were 145 emu g{sup −1} and 131 emu g{sup −1}, respectively. The measured saturation magnetizations are in good agreement with data obtained from TEM, XRD and Mössbauer spectroscopy.

  9. Passive sensor systems for nuclear material monitoring

    International Nuclear Information System (INIS)

    Simpson, M.L.; Boatner, L.A.; Holcomb, D.E.; McElhaney, S.A.; Mihalczo, J.T.; Muhs, J.D.; Roberts, M.R.; Hill, N.W.

    1993-01-01

    Passive fiber optic sensor systems capable of confirming the presence of special nuclear materials in storage or process facilities are being developed at Oak Ridge National Laboratory (ORNL). These sensors provide completely passive, remote measurement capability. No power supplies, amplifiers, or other active components that could degrade system reliability are required at the sensor location. ORNL, through its research programs in scintillator materials, has developed a variety of materials for use in alpha-, beta-, gamma-, and neutron-sensitive scintillator detectors. In addition to sensors for measuring radiation flux, new sensor materials have been developed which are capable of measuring weight, temperature, and source location. An example of a passive sensor for temperature measurement is the combination of a thermophosphor (e.g., rare-earth activated Y 2 O 3 ) with 6 LiF (95% 6 Li). This combination results in a new class of scintillators for thermal neutrons that absorb energy from the radiation particles and remit the energy as a light pulse, the decay rate of which, over a specified temperature range, is temperature dependent. Other passive sensors being developed include pressure-sensitive triboluminescent materials, weight-sensitive silicone rubber fibers, scintillating fibers, and other materials for gamma and neutron detection. The light from the scintillator materials of each sensor would be sent through optical fibers to a monitoring station, where the attribute quantity could be measured and compared with previously recorded emission levels. Confirmatory measurement applications of these technologies are being evaluated to reduce the effort, costs, and employee exposures associated with inventorying stockpiles of highly enriched uranium at the Oak Ridge Y-12 Plant

  10. Integration of active and passive polymer optics

    DEFF Research Database (Denmark)

    Christiansen, Mads Brøkner; Schøler, Mikkel; Kristensen, Anders

    2007-01-01

    We demonstrate a wafer scale fabrication process for integration of active and passive polymer optics: Polymer DFB lasers and waveguides. Polymer dye DFB lasers are fabricated by combined nanoimprint and photolithography (CNP). The CNP fabrication relies on an UV transparent stamp with nm sized...... wavelength from temperature and refractive index changes in the surroundings is investigated, pointing towards the use of the described fabrication method for on-chip polymer sensor systems....

  11. Passive self-cleaning aerosol scrubber

    International Nuclear Information System (INIS)

    Postma, A.K.

    1981-01-01

    A hybrid gas scrubbing system is described, which includes features of both a pool type scrubber and a sand or ground filter, for use on nuclear reactor containment buildings to limit release of aerosol particles and absorbable gases, including radio-active materials, during postulated major accidents. The system requires no energy while in the passive state and no active energy other than pressurization of the stream of gas being scrubbed. (U.K.)

  12. Carbohydrate plasma expanders for passive tumor targeting

    DEFF Research Database (Denmark)

    Hoffmann, Stefan; Caysa, Henrike; Kuntsche, Judith

    2013-01-01

    The objective of this study was to investigate the suitability of carbohydrate plasma volume expanders as a novel polymer platform for tumor targeting. Many synthetic polymers have already been synthesized for targeted tumor therapy, but potential advantages of these carbohydrates include inexpen...... was characterized in human colon carcinoma xenograft bearing nude mice. A tumor specific accumulation of HES 450 was observed, which proves it’s potential as carrier for passive tumor targeting....

  13. Passive low energy cooling of buildings

    CERN Document Server

    Givoni, Baruch

    1994-01-01

    A practical sourcebook for building designers, providing comprehensive discussion of the impact of basic architectural choices on cooling efficiency, including the layout and orientation of the structure, window size and shading, exterior color, and even the use of plantings around the site. All major varieties of passive cooling systems are presented, with extensive analysis of performance in different types of buildings and in different climates: ventilation; radiant cooling; evaporative cooling; soil cooling; and cooling of outdoor spaces.

  14. The passive house, a showbag; Wundertuete Passivhaus

    Energy Technology Data Exchange (ETDEWEB)

    Mardo, Dietrich; Unselt, Roland

    2011-03-07

    The contribution was written in close cooperation with Roland Unselt, graduate building operation engineer. In No. 4/2010, Ronald Unselt stated his critical and clear views on heat pumps. Here, he looks back on 20 years of construction of low-energy and passive buildings. He outlines the technical limits and identifies weak points and deficiencies. He shows problematic aspects and also practicable solutions that have been tried successfully.

  15. Moisture Conditions in Passive House Wall Constructions

    OpenAIRE

    Gullbrekken, Lars; Geving, Stig; Time, Berit; Andresen, Inger

    2015-01-01

    Buildings for the future, i.e zero emission buildings and passive houses, will need well insulated building envelopes, which includes increased insulation thicknesses for roof, wall and floor constructions. Increased insulation thicknesses may cause an increase in moisture levels and thereby increased risk of mold growth. There is need for increased knowledge about moisture levels in wood constructions of well insulated houses, to ensure robust and moisture safe solutions. Monitoring of w...

  16. Characterization of tetraethylene glycol passivated iron nanoparticles

    International Nuclear Information System (INIS)

    Nunes, Eloiza da Silva; Viali, Wesley Renato; Silva, Sebastião William da; Coaquira, José Antonio Huamaní; Garg, Vijayendra Kumar; Oliveira, Aderbal Carlos de; Morais, Paulo César; Jafelicci Júnior, Miguel

    2014-01-01

    Graphical abstract: - Highlights: • Metallic iron nanoparticles were passivated in tetraethylene glycol media. • Passivated nanoparticles presented pomegranate-like core@shell structure. • Passivation of metallic iron correlates with the tetraethylene glycol degradation. • Boron enriched metallic iron phase was more susceptible to oxidation. • The iron oxide shell was identified as Fe 3 O 4 with a mass fraction of 43:53 related to αFe. - Abstract: The present study describes the synthesis and characterization of iron@iron oxide nanoparticles produced by passivation of metallic iron in tetraethylene glycol media. Structural and chemical characterizations were performed using transmission electron microscopy (TEM), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), and Mössbauer spectroscopy. Pomegranate-like core@shell nanoparticulate material in the size range of 90–120 nm was obtained. According to quantitative phase analysis using Rietveld structure refinement the synthesized iron oxide was identified as magnetite (Fe 3 O 4 ) whereas the iron to magnetite mass fractions was found to be 47:53. These findings are in good agreement with the data obtained from Mössbauer and thermal gravimetric analysis (TGA). The XPS data revealed the presence of a surface organic layer with higher hydrocarbon content, possibly due to the tetraethylene glycol thermal degradation correlated with iron oxidation. The room-temperature (300 K) saturation magnetization measured for the as-synthesized iron and for the iron–iron oxide were 145 emu g −1 and 131 emu g −1 , respectively. The measured saturation magnetizations are in good agreement with data obtained from TEM, XRD and Mössbauer spectroscopy

  17. Radiation resistant passivation of silicon solar cells

    International Nuclear Information System (INIS)

    Swanson, R.M.; Gan, J.Y.; Gruenbaum, P.E.

    1991-01-01

    This patent describes a silicon solar cell having improved stability when exposed to concentrated solar radiation. It comprises a body of silicon material having a major surface for receiving radiation, a plurality of p and n conductivity regions in the body for collecting electrons and holes created by impinging radiation, and a passivation layer on the major surface including a first layer of silicon oxide in contact with the body and a polycrystalline silicon layer on the first layer of silicon oxide

  18. ParABS Systems of the Four Replicons of Burkholderia cenocepacia: New Chromosome Centromeres Confer Partition Specificity†

    Science.gov (United States)

    Dubarry, Nelly; Pasta, Franck; Lane, David

    2006-01-01

    Most bacterial chromosomes carry an analogue of the parABS systems that govern plasmid partition, but their role in chromosome partition is ambiguous. parABS systems might be particularly important for orderly segregation of multipartite genomes, where their role may thus be easier to evaluate. We have characterized parABS systems in Burkholderia cenocepacia, whose genome comprises three chromosomes and one low-copy-number plasmid. A single parAB locus and a set of ParB-binding (parS) centromere sites are located near the origin of each replicon. ParA and ParB of the longest chromosome are phylogenetically similar to analogues in other multichromosome and monochromosome bacteria but are distinct from those of smaller chromosomes. The latter form subgroups that correspond to the taxa of their hosts, indicating evolution from plasmids. The parS sites on the smaller chromosomes and the plasmid are similar to the “universal” parS of the main chromosome but with a sequence specific to their replicon. In an Escherichia coli plasmid stabilization test, each parAB exhibits partition activity only with the parS of its own replicon. Hence, parABS function is based on the independent partition of individual chromosomes rather than on a single communal system or network of interacting systems. Stabilization by the smaller chromosome and plasmid systems was enhanced by mutation of parS sites and a promoter internal to their parAB operons, suggesting autoregulatory mechanisms. The small chromosome ParBs were found to silence transcription, a property relevant to autoregulation. PMID:16452432

  19. Inherent/passive safety in fusion power plants

    International Nuclear Information System (INIS)

    Piet, S.J.; Crocker, J.G.

    1986-01-01

    The concept of inherent or passive safety for fusion energy is explored, defined, and partially quantified. Four levels of safety assurance are defined, which range from true inherent safety to passive safety to protection via active engineered safeguard systems. Fusion has the clear potential for achieving inherent or passive safety, which should be an objective of fusion research and design. Proper material choice might lead to both inherent/passive safety and high mass power density, improving both safety and economics. When inherent or passive safety is accomplished, fusion will be well on the way to achieving its ultimate potential and to be a truly superior energy source for the future

  20. Passive safety systems for integral reactors

    International Nuclear Information System (INIS)

    Kuul, V.S.; Samoilov, O.B.

    1996-01-01

    In this paper, a wide range of passive safety systems intended for use on integral reactors is considered. The operation of these systems relies on natural processes and does not require external power supplies. Using these systems, there is the possibility of preventing serious consequences for all classes of accidents including reactivity, loss-of-coolant and loss of heat sink as well as severe accidents. Enhancement of safety system reliability has been achieved through the use of self-actuating devices, capable of providing passive initiation of protective and isolation systems, which respond immediately to variations in the physical parameters of the fluid in the reactor or in a guard vessel. For beyond design base accidents accompanied by complete loss of heat removal capability, autonomous self-actuated ERHR trains have been proposed. These trains are completely independent of the secondary loops and need no action to isolate them from the steam turbine plant. Passive safety principles have been consistently implemented in AST-500, ATETS-200 and VPBER 600 which are new generation NPPs developed by OKBM. Their main characteristic is enhanced stability over a wide range of internal and external emergency initiators. (author). 10 figs

  1. Passive behaviour of zirconium, hafnium and niobium

    International Nuclear Information System (INIS)

    Hornkjoel, S.

    1990-01-01

    The paper deals mainly with the results of stationary and transient polarization measurements together with capacitance measurements on passive electrodes of Zr, Hf and Nb over the entire pH-scale. The passive current densities are exstremely low, and essentially both pH and potential independent, exept for Nb at high pH. The extrapolated potential of zero inverse capacitance seems to be different from the extrapolated potential of zero film thickness for Zr and Hf, but not for Nb. The potential versus time curves at constant current show a downwards bending for Zr and Hf. It is shown that the pitting potentials of Zr and Hf are dependent of the concentration of halide ions and the type of halide ion, but not on pH. It is also shown that the pitting induction is second-order stimulated by chloride ions and first-order hindered by sulphate ions. Results from electron transfer reactions on passive niobium are reported. 9 refs

  2. Sum rules and constraints on passive systems

    International Nuclear Information System (INIS)

    Bernland, A; Gustafsson, M; Luger, A

    2011-01-01

    A passive system is one that cannot produce energy, a property that naturally poses constraints on the system. A system in convolution form is fully described by its transfer function, and the class of Herglotz functions, holomorphic functions mapping the open upper half-plane to the closed upper half-plane, is closely related to the transfer functions of passive systems. Following a well-known representation theorem, Herglotz functions can be represented by means of positive measures on the real line. This fact is exploited in this paper in order to rigorously prove a set of integral identities for Herglotz functions that relate weighted integrals of the function to its asymptotic expansions at the origin and infinity. The integral identities are the core of a general approach introduced here to derive sum rules and physical limitations on various passive physical systems. Although similar approaches have previously been applied to a wide range of specific applications, this paper is the first to deliver a general procedure together with the necessary proofs. This procedure is described thoroughly and exemplified with examples from electromagnetic theory.

  3. Passivity-Based Control of Electric Machines

    Energy Technology Data Exchange (ETDEWEB)

    Nicklasson, P.J.

    1996-12-31

    This doctoral thesis presents new results on the design and analysis of controllers for a class of electric machines. Nonlinear controllers are derived from a Lagrangian model representation using passivity techniques, and previous results on induction motors are improved and extended to Blondel-Park transformable machines. The relation to conventional techniques is discussed, and it is shown that the formalism introduced in this work facilitates analysis of conventional methods, so that open questions concerning these methods may be resolved. In addition, the thesis contains the following improvements of previously published results on the control of induction motors: (1) Improvement of a passivity-based speed/position controller, (2) Extension of passivity-based (observer-less and observer-based) controllers from regulation to tracking of rotor flux norm, (3) An extension of the classical indirect FOC (Field-Oriented Control) scheme to also include global rotor flux norm tracking, instead of only torque tracking and rotor flux norm regulation. The design is illustrated experimentally by applying the proposed control schemes to a squirrel-cage induction motor. The results show that the proposed methods have advantages over previous designs with respect to controller tuning, performance and robustness. 145 refs., 21 figs.

  4. Brookfield Homes Passive House Performance Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Herk, A. [IBACOS, Inc., Pittsburgh, PA (United States); Poerschke, A. [IBACOS, Inc., Pittsburgh, PA (United States); Beach, R. [IBACOS, Inc., Pittsburgh, PA (United States)

    2016-02-04

    In 2012-2013, IBACOS worked with a builder, Brookfield Homes in Denver, Colorado, to design and construct a Passive House certified model home. IBACOS used several modeling programs and calculation methods to complete the final design package along with Brookfield's architect KGA Studio. This design package included upgrades to the thermal enclosure, basement insulation, windows, and heating, ventilation, and air conditioning. Short-term performance testing in the Passive House was done during construction and after construction. Testing with a blower door indicated that whole-building air leakage to the outside was 324 CFM and 0.60 ACH50. The other two test homes had little short-term testing done post-construction by the local energy rater. IBACOS then monitored the energy consumption and whole-house comfort conditions of that occupied Passive House after one year of operation and compared the monitoring results to those for two other occupied test houses in the same area with similar square footage but slightly different floor plans. IBACOS also assisted the builder, Brookfield Homes, in researching design scenarios for Zero Energy Ready Home and ENERGY STAR acceptance levels. IBACOS also assisted Brookfield in conceptualizing product for Denver's Brighton Heights area. Brookfield was considering building to Zero Energy Ready Home standards in that location. IBACOS provided strategies that Brookfield may draw from in the event the builder chooses to pursue a Zero Energy Ready Home plan for that market.

  5. Active or passive systems? The EPR approach

    International Nuclear Information System (INIS)

    Bonhomme, N.; Py, J.P.

    1996-01-01

    In attempting to review how EPR is contemplated to meet requirements applicable to future nuclear power plants, the authors indicate where they see the markets and the corresponding unit sizes for the EPR which is a generic key factor for competitiveness. There are no reason in industrialized countries, other than USA (where the investment and amortizing practices under control by Public Utility Commission are quite particular), not to build future plants in the 1000 to 1500 MWe range. Standardization, which has been actively applied all along the French program and for the Konvoi plants, does not prevent evolution and allows to concentrate large engineering effort in smooth realization of plants and achieve actual construction and commissioning without significant delays. In order to contribute to public trust renewal, a next generation of power reactors should be fundamentally less likely to incur serious accidents. To reach this goal the best of passive and active systems must be considered without forgetting that the most important source of knowledge is construction and operating experience. Criteria to assess passive systems investigated for possible implementation in the EPR, such as simplicity of design, impact on plant operation, safety and cost, are discussed. Examples of the principal passive systems investigated are described and reasons why they have been dropped after screening through the criteria are given. (author). 11 figs

  6. A passive radon dosemeter suitable for workplaces

    International Nuclear Information System (INIS)

    Orlando, C.; Orlando, P.; Patrizii, L.; Tommasino, L.; Tonnarini, S.; Trevisi, R.; Viola, P.

    2002-01-01

    The results obtained in different international intercomparisons on passive radon monitors have been analysed with the aim of identifying a suitable radon monitoring device for workplaces. From this analysis, the passive radon device, first developed for personal dosimetry in mines by the National Radiation Protection Board, UK (NRPB), has shown the most suitable set of characteristics. This radon monitor consists of a diffusion chamber, made of conductive plastic with less than 2 cm height, containing a CR-39 film (Columbia Resin 1939), as track detector. Radon detectors in workplaces may be exposed only during the working hours, thus requiring the storage of the detectors in low-radon zones when not exposed. This paper describes how this problem can be solved. Since track detectors are also efficient neutron dosemeters, care should be taken when radon monitors are used in workplaces, where they may be exposed to neutrons, such as on high altitude mountains, in the surroundings of high energy X ray facilities (where neutrons are produced by (gamma, n) reactions) or around high energy particle accelerators. To this end, the response of these passive radon monitors to high energy neutron fields has been investigated. (author)

  7. Passive safety systems for integral reactors

    Energy Technology Data Exchange (ETDEWEB)

    Kuul, V S; Samoilov, O B [OKB Mechanical Engineering (Russian Federation)

    1996-12-01

    In this paper, a wide range of passive safety systems intended for use on integral reactors is considered. The operation of these systems relies on natural processes and does not require external power supplies. Using these systems, there is the possibility of preventing serious consequences for all classes of accidents including reactivity, loss-of-coolant and loss of heat sink as well as severe accidents. Enhancement of safety system reliability has been achieved through the use of self-actuating devices, capable of providing passive initiation of protective and isolation systems, which respond immediately to variations in the physical parameters of the fluid in the reactor or in a guard vessel. For beyond design base accidents accompanied by complete loss of heat removal capability, autonomous self-actuated ERHR trains have been proposed. These trains are completely independent of the secondary loops and need no action to isolate them from the steam turbine plant. Passive safety principles have been consistently implemented in AST-500, ATETS-200 and VPBER 600 which are new generation NPPs developed by OKBM. Their main characteristic is enhanced stability over a wide range of internal and external emergency initiators. (author). 10 figs.

  8. Active or passive systems? The EPR approach

    Energy Technology Data Exchange (ETDEWEB)

    Bonhomme, N [Nuclear Power International, Cedex (France); Py, J P [FRAMATOME, Cedex (France)

    1996-12-01

    In attempting to review how EPR is contemplated to meet requirements applicable to future nuclear power plants, the authors indicate where they see the markets and the corresponding unit sizes for the EPR which is a generic key factor for competitiveness. There are no reason in industrialized countries, other than USA (where the investment and amortizing practices under control by Public Utility Commission are quite particular), not to build future plants in the 1000 to 1500 MWe range. Standardization, which has been actively applied all along the French program and for the Konvoi plants, does not prevent evolution and allows to concentrate large engineering effort in smooth realization of plants and achieve actual construction and commissioning without significant delays. In order to contribute to public trust renewal, a next generation of power reactors should be fundamentally less likely to incur serious accidents. To reach this goal the best of passive and active systems must be considered without forgetting that the most important source of knowledge is construction and operating experience. Criteria to assess passive systems investigated for possible implementation in the EPR, such as simplicity of design, impact on plant operation, safety and cost, are discussed. Examples of the principal passive systems investigated are described and reasons why they have been dropped after screening through the criteria are given. (author). 11 figs.

  9. Introducing passive matched field acoustic tomography

    International Nuclear Information System (INIS)

    Gasparini, O.; Camporeale, C.; Crise, A.

    1997-01-01

    In acoustic tomography sea-basin environmental parameters such as temperature profiles and current-velocities are derived, when ray propagation models are adopted, by the travel time estimates relative to the identifiable ray paths. The transmitted signals are either single frequency, or impulsive, or intermittent and deterministic. When the wavelength is comparable with the scale lengths present in the propagation scenario, Matched Field Tomography (MFT) is used, entailing the consideration of waveguide modes instead of rays. A new concept in tomography is introduced in the paper, that employs passively the noise emitted by ships of opportunity (cargoes, ferries) as source signals. The passive technique is acoustic-pollution-free, and if a basin is selected in which a regular ship traffic occurs data can be received on a regular schedule, with no transmission cost. A novel array pre-processor for passive tomography is introduced, such that the signal structure at the pre-processor output in nearly the same as that obtainable in the case of single-frequency source signals

  10. Columbia County Habitat for Humanity Passive Townhomes

    Energy Technology Data Exchange (ETDEWEB)

    Dentz, Jordan [The Advanced Residential Integrated Energy Solutions Collaborative, New York, NY (United States); Alaigh, Kunal [The Advanced Residential Integrated Energy Solutions Collaborative, New York, NY (United States); Dadia, Devanshi [The Advanced Residential Integrated Energy Solutions Collaborative, New York, NY (United States)

    2016-03-18

    Columbia County (New York) Habitat for Humanity built a pair of townhomes to Passive House criteria with the purpose of exploring approaches for achieving Passive House performance and to eventually develop a prototype design for future projects. The project utilized a 2x6 frame wall with a structural insulated panel curtain wall and a ventilated attic over a sealed OSB ceiling air barrier. Mechanical systems include a single head, wall mounted ductless mini-split heat pump in each unit and a heat recovery ventilator. Costs were $26,000 per unit higher for Passive House construction compared with the same home built to ENERGY STAR version 3 specifications, representing about 18% of total construction cost. This report discusses the cost components, energy modeling results and lessons from construction. Two alternative ventilation systems are analyzed: a central system; and, a point-source system with small through-wall units distributed throughout the house. The report includes a design and cost analysis of these two approaches.

  11. Serum suPAR in patients with FSGS: trash or treasure?

    Science.gov (United States)

    Maas, Rutger J H; Deegens, Jeroen K J; Wetzels, Jack F M

    2013-07-01

    The urokinase-type plasminogen activator receptor (uPAR) has important functions in cell migration. uPAR can be shed from the cell membrane resulting in soluble uPAR (suPAR). Further cleavage gives rise to shorter fragments with largely unknown functions. Recent studies have demonstrated that both overexpression of uPAR on podocytes and the administration of suPAR cause proteinuria in mice. The common pathogenic mechanism involves the activation of podocyte β3-integrin. Increased activation of β3-integrin is also observed in patients with focal and segmental glomerulosclerosis (FSGS). These observations form the basis for the hypothesis that suPAR may be the circulating factor causing FSGS. A recent study fosters this idea by demonstrating increased suPAR levels in the serum of patients with FSGS and reporting an association with recurrence after transplantation and response to plasmapheresis. However, this study was heavily biased, and subsequent studies have given conflicting results. Although the experimental work is very suggestive, at present there is no proof that any known human suPAR fragment causes FSGS in humans. We therefore suggest that the measurement of suPAR using currently available assays has absolutely no value at the present time in decision-making in routine clinical practice.

  12. PAR-2 expression in the gingival crevicular fluid reflects chronic periodontitis severity

    Directory of Open Access Journals (Sweden)

    Henrique FUKUSHIMA

    Full Text Available Abstract Recent studies investigating protease-activated receptor type 2 (PAR-2 suggest an association between the receptor and periodontal inflammation. It is known that gingipain, a bacterial protease secreted by the important periodontopathogen Porphyromonas gingivalis can activate PAR-2. Previous studies by our group found that PAR-2 is overexpressed in the gingival crevicular fluid (GCF of patients with moderate chronic periodontitis (MP. The present study aimed at evaluating whether PAR-2 expression is associated with chronic periodontitis severity. GCF samples and clinical parameters, including plaque and bleeding on probing indices, probing pocket depth and clinical attachment level, were collected from the control group (n = 19 at baseline, and from MP patients (n = 19 and severe chronic periodontitis (SP (n = 19 patients before and 6 weeks after periodontal non-surgical treatment. PAR-2 and gingipain messenger RNA (mRNA in the GCF of 4 periodontal sites per patient were evaluated by Reverse Transcription Polymerase Chain Reaction (RT-qPCR. PAR-2 and gingipain expressions were greater in periodontitis patients than in control group patients. In addition, the SP group presented increased PAR-2 and gingipain mRNA levels, compared with the MP group. Furthermore, periodontal treatment significantly reduced (p <0.05 PAR-2 expression in patients with periodontitis. In conclusion, PAR-2 is associated with chronic periodontitis severity and with gingipain levels in the periodontal pocket, thus suggesting that PAR-2 expression in the GCF reflects the severity of destruction during periodontal infection.

  13. Structures of actin-like ParM filaments show architecture of plasmid-segregating spindles.

    Science.gov (United States)

    Bharat, Tanmay A M; Murshudov, Garib N; Sachse, Carsten; Löwe, Jan

    2015-07-02

    Active segregation of Escherichia coli low-copy-number plasmid R1 involves formation of a bipolar spindle made of left-handed double-helical actin-like ParM filaments. ParR links the filaments with centromeric parC plasmid DNA, while facilitating the addition of subunits to ParM filaments. Growing ParMRC spindles push sister plasmids to the cell poles. Here, using modern electron cryomicroscopy methods, we investigate the structures and arrangements of ParM filaments in vitro and in cells, revealing at near-atomic resolution how subunits and filaments come together to produce the simplest known mitotic machinery. To understand the mechanism of dynamic instability, we determine structures of ParM filaments in different nucleotide states. The structure of filaments bound to the ATP analogue AMPPNP is determined at 4.3 Å resolution and refined. The ParM filament structure shows strong longitudinal interfaces and weaker lateral interactions. Also using electron cryomicroscopy, we reconstruct ParM doublets forming antiparallel spindles. Finally, with whole-cell electron cryotomography, we show that doublets are abundant in bacterial cells containing low-copy-number plasmids with the ParMRC locus, leading to an asynchronous model of R1 plasmid segregation.

  14. PAR-1 contributes to the innate immune response during viral infection

    Science.gov (United States)

    Antoniak, Silvio; Owens, A. Phillip; Baunacke, Martin; Williams, Julie C.; Lee, Rebecca D.; Weithäuser, Alice; Sheridan, Patricia A.; Malz, Ronny; Luyendyk, James P.; Esserman, Denise A.; Trejo, JoAnn; Kirchhofer, Daniel; Blaxall, Burns C.; Pawlinski, Rafal; Beck, Melinda A.; Rauch, Ursula; Mackman, Nigel

    2013-01-01

    Coagulation is a host defense system that limits the spread of pathogens. Coagulation proteases, such as thrombin, also activate cells by cleaving PARs. In this study, we analyzed the role of PAR-1 in coxsackievirus B3–induced (CVB3-induced) myocarditis and influenza A infection. CVB3-infected Par1–/– mice expressed reduced levels of IFN-β and CXCL10 during the early phase of infection compared with Par1+/+ mice that resulted in higher viral loads and cardiac injury at day 8 after infection. Inhibition of either tissue factor or thrombin in WT mice also significantly increased CVB3 levels in the heart and cardiac injury compared with controls. BM transplantation experiments demonstrated that PAR-1 in nonhematopoietic cells protected mice from CVB3 infection. Transgenic mice overexpressing PAR-1 in cardiomyocytes had reduced CVB3-induced myocarditis. We found that cooperative signaling between PAR-1 and TLR3 in mouse cardiac fibroblasts enhanced activation of p38 and induction of IFN-β and CXCL10 expression. Par1–/– mice also had decreased CXCL10 expression and increased viral levels in the lung after influenza A infection compared with Par1+/+ mice. Our results indicate that the tissue factor/thrombin/PAR-1 pathway enhances IFN-β expression and contributes to the innate immune response during single-stranded RNA viral infection. PMID:23391721

  15. Par-4-mediated recruitment of Amida to the actin cytoskeleton leads to the induction of apoptosis

    International Nuclear Information System (INIS)

    Boosen, Meike; Vetterkind, Susanne; Koplin, Ansgar; Illenberger, Susanne; Preuss, Ute

    2005-01-01

    Par-4 (prostate apoptosis response-4) sensitizes cells to apoptotic stimuli, but the exact mechanisms are still poorly understood. Using Par-4 as bait in a yeast two-hybrid screen, we identified Amida as a novel interaction partner, a ubiquitously expressed protein which has been suggested to be involved in apoptotic processes. Complex formation of Par-4 and Amida occurs in vitro and in vivo and is mediated via the C-termini of both proteins, involving the leucine zipper of Par-4. Amida resides mainly in the nucleus but displays nucleo-cytoplasmic shuttling in heterokaryons. Upon coexpression with Par-4 in REF52.2 cells, Amida translocates to the cytoplasm and is recruited to actin filaments by Par-4, resulting in enhanced induction of apoptosis. The synergistic effect of Amida/Par-4 complexes on the induction of apoptosis is abrogated when either Amida/Par-4 complex formation or association of these complexes with the actin cytoskeleton is impaired, indicating that the Par-4-mediated relocation of Amida to the actin cytoskeleton is crucial for the pro-apoptotic function of Par-4/Amida complexes in REF52.2 cells. The latter results in enhanced phosphorylation of the regulatory light chain of myosin II (MLC) as has previously been shown for Par-4-mediated recruitment of DAP-like kinase (Dlk), suggesting that the recruitment of nuclear proteins involved in the regulation of apoptotic processes to the actin filament system by Par-4 represents a potent mechanism how Par-4 can trigger apoptosis

  16. Passive energy standard in building as a perspective of sustainable development - first passive houses in Croatia

    International Nuclear Information System (INIS)

    Miscevic, Lj.

    2005-01-01

    The paper presents the projects and implementation of the first passive family houses in Croatia. The Croatian Solar House (CSH) is a national technological-development project by a group of authors, which is based on passive house standard as an energy-terms point of departure. The House EV1 is a wood-made passive house under construction, while the House M4 is the first passive house in Croatia made in poro-concrete and reinforced concrete made ceiling slabs. Both houses comply with the heating energy consumption requirements under the passive house definition, i.e., the annual consumption does not exceed 15 kWh/m2. These houses are also referred to as 'houses without heating', 'houses with thermal comfort without heating' or 'one-liter houses' because their consumption is equivalent to one liter of fuel oil by one square meter a year. Assuming the high-value thermal protection, passive house is equipped with an installation system which houses a heat pump and ventilation system for continuous introduction of fresh air indoors. The use of renewable energy sources enabled the accomplishment by far the biggest energy savings in the construction industry, ensuring optimal conditions for healthy living without harmful gas emissions. Since 1990 there is an exponential growth of constructed passive houses in Europe. Germany is leading this trend with total of 150,000 free-standing houses, house raw units or residential units in small multi-apartment buildings. The research project-program of the European Union: Cost Efficiency Passive Houses as European Union Standard (CEPHEUS) has confirmed, by scientific monitoring during several years, the energy- and cost-efficiency of such architecture and construction model in more than 250 units in Germany, France, Austria and Switzerland. Therefore the passive house is proposed as a standard for residential architecture and construction, but also for general construction of all functional types of non-residential architecture

  17. The development and study on passive natural circulation

    International Nuclear Information System (INIS)

    Zhou Tao; Li Jingjing; Ju Zhongyun; Huang Yanping; Xiao Zejun

    2013-01-01

    Passive natural circulation is getting more and more important in the field of nuclear power engineering. This article cited a passive natural circulation in the nuclear power system application, analyzed the potential problems during operation, described current mathematical research methods of the reliability of passive natural cycle analysis, briefly summarized the advantages and disadvantages of these methods, and finally got an outlook of the direction of passive natural circulation. Since the presence of passive natural circulation may get failure, sufficient attention and active research should be paid in response to the physical process failure of the running passive natural circulation system and its reliability. To ensure system security during the operation, the operation process should combine active with non-dynamic; while selecting an accurate model, perfect passive reliability analysis methods to achieve accurate theoretical calculations and experimental verification. (authors)

  18. Electropotential measurements of passivation and corrosion of steel coupons

    International Nuclear Information System (INIS)

    Petit, G.S.; Wright, R.R.

    1977-02-01

    There is considerable interest at the Oak Ridge Gaseous Diffusion Plant (ORGDP) in the preparation of mild steel to resist corrosion (passivation) both in moist air and uranium hexafluoride (UF 6 ) environments. Steel prepared by the usual procedures to prevent rusting, such as oiling, plastic coating, painting, or phosphating, cannot be used in the presence of UF 6 . Tests have shown that a chromate treatment or an ammoniacal citrate treatment for passivation are effective. The electropotential behavior of these two passivation treatments is described. The initial electropotential measurement, when compared to that of an unpassivated coupon, gives the electropotential degree in volts of passivation. Continual exposure in the test, when compared to the unpassivated coupon, gives a profile of the durability of the passivation film. The chromate passivation treatment was slightly superior to the citrate passivation

  19. Reliability of thermal-hydraulic passive safety systems

    International Nuclear Information System (INIS)

    D'Auria, F.; Araneo, D.; Pierro, F.; Galassi, G.

    2014-01-01

    The scholar will be informed of reliability concepts applied to passive system adopted for nuclear reactors. Namely, for classical components and systems the failure concept is associated with malfunction of breaking of hardware. In the case of passive systems the failure is associated with phenomena. A method for studying the reliability of passive systems is discussed and is applied. The paper deals with the description of the REPAS (Reliability Evaluation of Passive Safety System) methodology developed by University of Pisa (UNIPI) and with results from its application. The general objective of the REPAS methodology is to characterize the performance of a passive system in order to increase the confidence toward its operation and to compare the performances of active and passive systems and the performances of different passive systems

  20. Implications of passive safety based on historical industrial experience

    International Nuclear Information System (INIS)

    Forsberg, C.W.

    1988-01-01

    In the past decade, there have been multiple proposals for applying different technologies to achieve passively safe light water reactors (LWRs). A key question for all such concepts is, ''What are the gains in safety, costs, and reliability for passive safety systems.'' Using several types of historical data, estimates have been made of gains from passive safety and operating systems, which are independent of technology. Proposals for passive safety in reactors usually have three characteristics: (1) Passive systems with no moving mechanical parts, (2) systems with far fewer components and (3) more stringent design criteria for safety-related and process systems. Each characteristic reduces the potential for an accident and may increase plant reliability. This paper addresses gains from items (1) and (2). Passive systems often allow adoption of more rigorous design criteria which would be either impossible or economically unfeasible for active systems. This important characteristic of passive safety systems cannot be easily addressed using historical industrial experience

  1. Scottish Passive House: Insights into Environmental Conditions in Monitored Passive Houses

    Directory of Open Access Journals (Sweden)

    Janice Foster

    2016-04-01

    Full Text Available Climate change and sustainability legislation in recent years has led to significant changes in construction approaches in the UK housing sector. This has resulted in the adoption of new building typologies, including the German Passivhaus (Passive House standard. This standard aims to improve occupant comfort and energy efficiency, potentially changing the ways in which homes operate and how occupants interact with them. With increasing construction of low energy dwellings, there is an emerging gap in knowledge in relation to occupant health and wellbeing, thermal comfort, and indoor air quality (IAQ. Using data collected from a two year Building Performance Evaluation (BPE study funded by Innovate UK, the environmental data (temperature, relative humidity and carbon dioxide concentrations from five Certified Passive House homes in Scotland was compared. The results demonstrate problems with overheating with peak temperatures exceeding 30 °C. Imbalanced mechanical ventilation with heat recovery (MVHR systems were identified in 80% of the dwellings and inadequate IAQ was found due to poor ventilation. Only one of the Passive Houses studied exhibited thermal conditions and IAQ which were, on the whole within Passive House parameters. This paper outlines the insights and the main issues of Scottish Passive House in the broader context of sustainability.

  2. Bacterial mitosis: Partitioning protein ParA oscillates in spiral-shaped structures and positions plasmids at mid-cell

    DEFF Research Database (Denmark)

    Ebersbach, G.; Gerdes, Kenn

    2004-01-01

    The par2 locus of Escherichia coli plasmid pB171 encodes oscillating ATPase ParA, DNA binding protein ParB and two cis-acting DNA regions to which ParB binds (parC1 and parC2). Three independent techniques were used to investigate the subcellular localization of plasmids carrying par2. In cells......A-GFP oscillated in spiral-shaped structures. Amino acid substitutions in ParA simultaneously abolished ParA spiral formation, oscillation and either plasmid localization or plasmid separation at mid-cell. Therefore, our results suggest that ParA spirals position plasmids at the middle of the bacterial nucleoid...

  3. Envenimation mortelle par morsure de serpent chez une femme ...

    African Journals Online (AJOL)

    Les auteurs rapportent un cas de morsure de serpent au niveau de la face chez une femme enceinte, dont l'évolution a été marquée par l'installation d'un oedème cervico-facial nécessitant une trachéotomie en urgence, et une mort foetale in utero avec troubles de l'hémostase responsable du décès maternel dans un ...

  4. Analysis of clinical features and visual outcomes of pars planitis.

    Science.gov (United States)

    Berker, Nilufer; Sen, Emine; Elgin, Ufuk; Atilgan, Cemile Ucgul; Dursun, Erdem; Yilmazbas, Pelin

    2018-04-01

    To evaluate the demographic characteristics, clinical features, treatment and outcomes of patients with pars planitis in a tertiary referral center in Turkey. Medical records of patients with pars planitis were retrospectively reviewed. The data including demographic and ocular features and treatment outcomes were recorded. The distribution of clinical findings and complications were evaluated according to age and gender groups. The changes in final BCVA compared to the initial BCVA were noted. Statistical analysis was performed using SPSS software (Version 18.0, SPSS Inc., Chicago, USA). Twenty-seven patients (54 eyes) were included in this study. 16 patients were male (59.3%), and 11 were female (40.7%). Mean age at diagnosis was 12.84 ± 8.26 (range 4-36) years. Mean follow-up period was 61.3 ± 52.15 (range 9-172) months. Mean BCVA was 0.58 ± 0.36 (range 0.03-1.00) (0.40 ± 0.45 logMAR) at presentation, and 0.81 ± 0.28 (range 0.10-1.00) (0.14 ± 0.27 logMAR) at final visit (P = 0.001). Vitreous inflammation (100%), vitreous haze (92.6%), snowballs (74.1%), snowbanks (66.7%), anterior chamber cells (66.7%) and peripheral retinal vascular sheathing (48.1%) were the most common presentations. Ocular complications included vitreous condensation (51.9%), cystoid macular edema (22.2%), cataract (18.5%), inferior peripheral retinal detachment (11.1%), glaucoma (5.6%) and vitreous hemorrhage (3.7%). Treatments included topical, periocular, intravitreal and systemic corticosteroids, immunosuppressives, peripheral laser photocoagulation and pars plana vitrectomy when needed. Pars planitis is an idiopathic chronic intermediate uveitis mostly affecting children and adolescents. In spite of its chronic nature with high potential of causing ocular complications, adequate treatment and close follow-up lead to favorable visual outcomes.

  5. Cartographie par carroyage et précision spatiale

    Directory of Open Access Journals (Sweden)

    Patrice LANGLOIS

    1998-03-01

    Full Text Available Dans le cadre d'une cartographie par carroyage, on étudie la désagrégation de variables zonales, en revenant sur l'hypothèse de l'équirépartition spatiale des populations. L'objectif est d'approcher des règles différenciées de désagrégation des variables en fusionnant des plans d'information de nature morphologique, topologique et environnementale.

  6. Inkjet Printed Radio Frequency Passive Components

    KAUST Repository

    McKerricher, Garret

    2015-12-01

    Inkjet printing is a mature technique for colourful graphic arts. It excels at customized, large area, high resolution, and small volume production. With the developments in conductive, and dielectric inks, there is potential for large area inkjet electronics fabrication. Passive radio frequency devices can benefit greatly from a printing process, since the size of these devices is defined by the frequency of operation. The large size of radio frequency passives means that they either take up expensive space “on chip” or that they are fabricated on a separate lower cost substrate and somehow bonded to the chips. This has hindered cost-sensitive high volume applications such as radio frequency identification tags. Substantial work has been undertaken on inkjet-printed conductors for passive antennas on microwave substrates and even paper, yet there has been little work on the printing of the dielectric materials aimed at radio frequency passives. Both the conductor and dielectric need to be integrated to create a multilayer inkjet printing process that is capable of making quality passives such as capacitors and inductors. Three inkjet printed dielectrics are investigated in this thesis: a ceramic (alumina), a thermal-cured polymer (poly 4 vinyl phenol), and a UV-cured polymer (acrylic based). For the conductor, both a silver nanoparticle ink as well as a custom in-house formulated particle-free silver ink are explored. The focus is on passives, mainly capacitors and inductors. Compared to low frequency electronics, radio frequency components have additional sensitivity regarding skin depth of the conductor and surface roughness, as well as dielectric constant and loss tangent of the dielectric. These concerns are investigated with the aim of making the highest quality components possible and to understand the current limitations of inkjet-fabricated radio frequency devices. An inkjet-printed alumina dielectric that provides quality factors of 200 and high

  7. PET imaging of urokinase-type plasminogen activator receptor (uPAR) in prostate cancer

    DEFF Research Database (Denmark)

    Skovgaard, Dorthe; Persson, Morten; Kjaer, Andreas

    2016-01-01

    Overexpression of urokinase-type plasminogen activator receptors (uPAR) represents an important biomarker for aggressiveness in most common malignant diseases, including prostate cancer (PC). Accordingly, uPAR expression either assessed directly in malignant PC tissue or assessed directly in plasma...... and prognostic imaging method. In this review, we will focus on the recent development of uPAR PET and the relevance within prostate cancer imaging. Novel antibody and small-molecule radiotracers-targeting uPAR, including a series of uPAR-targeting PET ligands, based on the high affinity peptide ligand AE105......, have been synthesized and tested in vitro and in vivo in preclinical murine xenograft models and, recently, in a first-ever clinical uPAR PET study in cancer patients, including patients with PC. In this phase I study, a high and specific uptake of the tracer 64Cu-DOTA-AE105 was found in both primary...

  8. Paracrine Apoptotic Effect of p53 Mediated by Tumor Suppressor Par-4

    Directory of Open Access Journals (Sweden)

    Ravshan Burikhanov

    2014-01-01

    Full Text Available The guardian of the genome, p53, is often mutated in cancer and may contribute to therapeutic resistance. Given that p53 is intact and functional in normal tissues, we harnessed its potential to inhibit the growth of p53-deficient cancer cells. Specific activation of p53 in normal fibroblasts selectively induced apoptosis in p53-deficient cancer cells. This paracrine effect was mediated by p53-dependent secretion of the tumor suppressor Par-4. Accordingly, the activation of p53 in normal mice, but not p53−/− or Par-4−/− mice, caused systemic elevation of Par-4, which induced apoptosis of p53-deficient tumor cells. Mechanistically, p53 induced Par-4 secretion by suppressing the expression of its binding partner, UACA, which sequesters Par-4. Thus, normal cells can be empowered by p53 activation to induce Par-4 secretion for the inhibition of therapy-resistant tumors.

  9. Electrochemical characterization of anode passivation mechanisms in copper electrorefining

    Science.gov (United States)

    Moats, Michael Scott

    Anode passivation can decrease productivity and quality while increasing costs in modern copper electrorefineries. This investigation utilized electrochemical techniques to characterize the passivation behavior of anode samples from ten different operating companies. It is believed that this collection of anodes is the most diverse set ever to be assembled to study the effect of anode composition on passivation. Chronopotentiometry was the main electrochemical technique, employing a current density of 3820 A m-2. From statistical analysis of the passivation characteristics, increasing selenium, tellurium, silver, lead and nickel were shown to accelerate passivation. Arsenic was the only anode impurity that inhibited passivation. Oxygen was shown to accelerate passivation when increased from 500 to 1500 ppm, but further increases did not adversely affect passivation. Nine electrolyte variables were also examined. Increasing the copper, sulfuric acid or sulfate concentration of the electrolyte accelerated passivation. Arsenic in the electrolyte had no effect on passivation. Chloride and optimal concentrations of thiourea and glue delayed passivation. Linear sweep voltammetry, cyclic voltammetry, and impedance spectroscopy provided complementary information. Analysis of the electrochemical results led to the development of a unified passivation mechanism. Anode passivation results from the formation of inhibiting films. Careful examination of the potential details, especially those found in the oscillations just prior to passivation, demonstrated the importance of slimes, copper sulfate and copper oxide. Slimes confine dissolution to their pores and inhibit diffusion. This can lead to copper sulfate precipitation, which blocks more of the surface area. Copper oxide forms because of the resulting increase in potential at the interface between the copper sulfate and anode. Ultimate passivation occurs when the anode potential is high enough to stabilize the oxide film in

  10. The link between exercise and titin passive stiffness.

    Science.gov (United States)

    Lalande, Sophie; Mueller, Patrick J; Chung, Charles S

    2017-09-01

    What is the topic of this review? This review focuses on how in vivo and molecular measurements of cardiac passive stiffness can predict exercise tolerance and how exercise training can reduce cardiac passive stiffness. What advances does it highlight? This review highlights advances in understanding the relationship between molecular (titin-based) and in vivo (left ventricular) passive stiffness, how passive stiffness modifies exercise tolerance, and how exercise training may be therapeutic for cardiac diseases with increased passive stiffness. Exercise can help alleviate the negative effects of cardiovascular disease and cardiovascular co-morbidities associated with sedentary behaviour; this may be especially true in diseases that are associated with increased left ventricular passive stiffness. In this review, we discuss the inverse relationship between exercise tolerance and cardiac passive stiffness. Passive stiffness is the physical property of cardiac muscle to produce a resistive force when stretched, which, in vivo, is measured using the left ventricular end diastolic pressure-volume relationship or is estimated using echocardiography. The giant elastic protein titin is the major contributor to passive stiffness at physiological muscle (sarcomere) lengths. Passive stiffness can be modified by altering titin isoform size or by post-translational modifications. In both human and animal models, increased left ventricular passive stiffness is associated with reduced exercise tolerance due to impaired diastolic filling, suggesting that increased passive stiffness predicts reduced exercise tolerance. At the same time, exercise training itself may induce both short- and long-term changes in titin-based passive stiffness, suggesting that exercise may be a treatment for diseases associated with increased passive stiffness. Direct modification of passive stiffness to improve exercise tolerance is a potential therapeutic approach. Titin passive stiffness itself may

  11. Calibrating passive sampling and passive dosing techniques to lipid based concentrations

    DEFF Research Database (Denmark)

    Mayer, Philipp; Schmidt, Stine Nørgaard; Annika, A.

    2011-01-01

    Equilibrium sampling into various formats of the silicone polydimethylsiloxane (PDMS) is increasingly used to measure the exposure of hydrophobic organic chemicals in environmental matrices, and passive dosing from silicone is increasingly used to control and maintain their exposure in laboratory...... coated vials and with Head Space Solid Phase Microextraction (HS-SPME) yielded lipid based concentrations that were in good agreement with each other, but about a factor of two higher than measured lipid-normalized concentrations in the organisms. Passive dosing was applied to bioconcentration...

  12. Four cases of endophthalmitis after 25-gauge pars plana vitrectomy

    Directory of Open Access Journals (Sweden)

    Mutoh T

    2012-08-01

    Full Text Available Tetsuya Mutoh, Koji Kadoya, Makoto ChikudaDepartment of Ophthalmology, Dokkyo Medical University Koshigaya Hospital, Koshigaya, Saitama, JapanAbstract: We report our recent experience with four cases of endophthalmitis (one male, three females after 25-gauge pars plana vitrectomy (PPV. One was a case of persistent cystoid macular edema caused by branch retinal vein occlusion, whereas the remaining three were cases of epiretinal membrane. Preoperative antibiotics before the first PPV procedure were not administered in three of the four cases. Endophthalmitis occurred 2–4 days after the first procedure in all cases, for which ceftazidime 2.0 mg/0.1 mL and vancomycin 1.0 mg/0.1 mL were injected into the vitreous cavity. This was followed by emergent 20-gauge PPV and intraocular lens removal using an infusion fluid containing ceftazidime and vancomycin. After the second PPV procedure, progress was good in three cases while retinal detachment occurred in the remaining case one month after surgery; this case required a third PPV procedure. Final best-corrected visual acuity ranged from 20/100 to 20/25 for the four cases. Bacterial cultures were negative after the second PPV procedure in all cases. In conclusion, postoperative endophthalmitis occurred in four of 502 cases (0.80% that underwent 25-gauge PPV at our hospital. It is important to minimize the incidence of endophthalmitis after 25-gauge PPV.Keywords: 25-gauge pars plana vitrectomy, endophthalmitis, incidence

  13. Stress reactions involving the pars interarticularis in young athletes

    Energy Technology Data Exchange (ETDEWEB)

    Jackson, D.W.; Wiltse, L.L.; Dingeman, R.D.; Hayes, M.

    A stress reaction involving the pars interarticularis of the lumbar spine was confirmed in seven young athletes with a positive technetium pyrophosphate bone scan. No pars defects were detectable on their lumbosacral roentgenograms, which included oblique views. The return to normal levels of radioactive uptake on repeat bone scans correlated closely with their clinical course. If the bony reaction is recognized early, it may heal at a subroentgenographic level and prevent the development of lumbar spondylolysis. These early lesions usually show unilateral increased uptake at one lumbar level on the bone scan and, initially, the athlete localizes the pain to the corresponding unilateral lumbar paraspinous area. The ''one-legged hyperextension test'' is positive on the ipsilateral side and aggravates the pain. Treatment consists of avoiding the aggravating activities and resting. The average time for return to pain-free competition was 7.3 months. These developing defects may be the source of considerable prolonged disability in the young athlete, particularly if undiagnosed and untreated.

  14. Stress reactions involving the pars interarticularis in young athletes

    International Nuclear Information System (INIS)

    Jackson, D.W.; Wiltse, L.L.; Dingeman, R.D.; Hayes, M.

    1981-01-01

    A stress reaction involving the pars interarticularis of the lumbar spine was confirmed in seven young athletes with a positive technetium pyrophosphate bone scan. No pars defects were detectable on their lumbosacral roentgenograms, which included oblique views. The return to normal levels of radioactive uptake on repeat bone scans correlated closely with their clinical course. If the bony reaction is recognized early, it may heal at a subroentgenographic level and prevent the development of lumbar spondylolysis. These early lesions usually show unilateral increased uptake at one lumbar level on the bone scan and, initially, the athlete localizes the pain to the corresponding unilateral lumbar paraspinous area. The ''one-legged hyperextension test'' is positive on the ipsilateral side and aggravates the pain. Treatment consists of avoiding the aggravating activities and resting. The average time for return to pain-free competition was 7.3 months. These developing defects may be the source of considerable prolonged disability in the young athlete, particularly if undiagnosed and untreated

  15. Réduction du risque d'infection par le VIH au Botswana - essais ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Au Botswana, ce sont les jeunes femmes qui sont le plus touchées par les nouvelles infections par le VIH. Le présent projet a pour but de réduire le nombre de nouveaux cas d'infection par le VIH, en particulier chez les femmes de 15 à 29 ans. Bien que l'on recense des cas de VIH/sida dans la plupart des régions du ...

  16. Passive nondestructive assay of nuclear materials

    International Nuclear Information System (INIS)

    Reilly, D.; Ensslin, N.; Smith, H. Jr.; Kreiner, S.

    1991-03-01

    The term nondestructive assay (NDA) is applied to a series of measurement techniques for nuclear fuel materials. The techniques measure radiation induced or emitted spontaneously from the nuclear material; the measurements are nondestructive in that they do not alter the physical or chemical state of the nuclear material. NDA techniques are characterized as passive or active depending on whether they measure radiation from the spontaneous decay of the nuclear material or radiation induced by an external source. This book emphasizes passive NDA techniques, although certain active techniques like gamma-ray absorption densitometry and x-ray fluorescence are discussed here because of their intimate relation to passive assay techniques. The principal NDA techniques are classified as gamma-ray assay, neutron assay, and calorimetry. Gamma-ray assay techniques are treated in Chapters 1--10. Neutron assay techniques are the subject of Chapters 11--17. Chapters 11--13 cover the origin of neutrons, neutron interactions, and neutron detectors. Chapters 14--17 cover the theory and applications of total and coincidence neutron counting. Chapter 18 deals with the assay of irradiated nuclear fuel, which uses both gamma-ray and neutron assay techniques. Chapter 19 covers perimeter monitoring, which uses gamma-ray and neutron detectors of high sensitivity to check that no unauthorized nuclear material crosses a facility boundary. The subject of Chapter 20 is attribute and semiquantitative measurements. The goal of these measurements is a rapid verification of the contents of nuclear material containers to assist physical inventory verifications. Waste and holdup measurements are also treated in this chapter. Chapters 21 and 22 cover calorimetry theory and application, and Chapter 23 is a brief application guide to illustrate which techniques can be used to solve certain measurement problems

  17. Ethical decision-making, passivity and pharmacy.

    Science.gov (United States)

    Cooper, R J; Bissell, P; Wingfield, J

    2008-06-01

    Increasing interest in empirical ethics has enhanced understanding of healthcare professionals' ethical problems and attendant decision-making. A four-stage decision-making model involving ethical attention, reasoning, intention and action offers further insights into how more than reasoning alone may contribute to decision-making. To explore how the four-stage model can increase understanding of decision-making in healthcare and describe the decision-making of an under-researched professional group. 23 purposively sampled UK community pharmacists were asked, in semi-structured interviews, to describe ethical problems in their work and how they were resolved. Framework analysis of transcribed interviews utilised the four decision-making stages, together with constant comparative methods and deviant-case analysis. Pharmacists were often inattentive and constructed problems in legal terms. Ethical reasoning was limited, but examples of appeals to consequences, the golden rule, religious faith and common-sense experience emerged. Ethical intention was compromised by frequent concern about legal prosecution. Ethical inaction was common, typified by pharmacists' failure to report healthcare professionals' bad practices, and ethical passivity emerged to describe these negative examples of the four decision-making stages. Pharmacists occasionally described more ethically active decision-making, but this often involved ethical uncertainty. The four decision-making stages are a useful tool in considering how healthcare professionals try to resolve ethical problems in practice. They reveal processes often ignored in normative theories, and their recognition and the emergence of ethical passivity indicates the complexity of decision-making in practice. Ethical passivity may be deleterious to patients' welfare, and concerns emerge about improving pharmacists' ethical training and promoting ethical awareness and responsibility.

  18. PAR-2 expression in the gingival crevicular fluid reflects chronic periodontitis severity.

    Science.gov (United States)

    Fukushima, Henrique; Alves, Vanessa Tubero Euzebio; Carvalho, Verônica Franco de; Ambrósio, Lucas Macedo Batitucci; Eichler, Rosangela Aparecida Dos Santos; Carvalho, Maria Helena Catelli de; Saraiva, Luciana; Holzhausen, Marinella

    2017-01-26

    Recent studies investigating protease-activated receptor type 2 (PAR-2) suggest an association between the receptor and periodontal inflammation. It is known that gingipain, a bacterial protease secreted by the important periodontopathogen Porphyromonas gingivalis can activate PAR-2. Previous studies by our group found that PAR-2 is overexpressed in the gingival crevicular fluid (GCF) of patients with moderate chronic periodontitis (MP). The present study aimed at evaluating whether PAR-2 expression is associated with chronic periodontitis severity. GCF samples and clinical parameters, including plaque and bleeding on probing indices, probing pocket depth and clinical attachment level, were collected from the control group (n = 19) at baseline, and from MP patients (n = 19) and severe chronic periodontitis (SP) (n = 19) patients before and 6 weeks after periodontal non-surgical treatment. PAR-2 and gingipain messenger RNA (mRNA) in the GCF of 4 periodontal sites per patient were evaluated by Reverse Transcription Polymerase Chain Reaction (RT-qPCR). PAR-2 and gingipain expressions were greater in periodontitis patients than in control group patients. In addition, the SP group presented increased PAR-2 and gingipain mRNA levels, compared with the MP group. Furthermore, periodontal treatment significantly reduced (p periodontitis. In conclusion, PAR-2 is associated with chronic periodontitis severity and with gingipain levels in the periodontal pocket, thus suggesting that PAR-2 expression in the GCF reflects the severity of destruction during periodontal infection.

  19. Passivation-free solid state battery

    Science.gov (United States)

    Abraham, Kuzhikalail M.; Peramunage, Dharmasena

    1998-01-01

    This invention pertains to passivation-free solid-state rechargeable batteries composed of Li.sub.4 Ti.sub.5 O.sub.12 anode, a solid polymer electrolyte and a high voltage cathode. The solid polymer electrolyte comprises a polymer host, such as polyacrylonitrile, poly(vinyl chloride), poly(vinyl sulfone), and poly(vinylidene fluoride), plasticized by a solution of a Li salt in an organic solvent. The high voltage cathode includes LiMn.sub.2 O.sub.4, LiCoO.sub.2, LiNiO.sub.2 and LiV.sub.2 O.sub.5 and their derivatives.

  20. Passive neutron dosemeter with activation detector

    Energy Technology Data Exchange (ETDEWEB)

    Valero L, C.; Banuelos F, A.; Guzman G, K. A.; Borja H, C. G.; Hernandez D, V. M.; Vega C, H. R., E-mail: fermineutron@yahoo.com [Universidad Autonoma de Zacatecas, Unidad Academica de Estudios Nucleares, Calle Cipres No. 10, Fracc. La Penuela, 98068 Zacatecas (Mexico)

    2011-10-15

    A passive neutron dosemeter with {sup 197}Au activation detector has been developed. The area dosemeter was made as a 20.5 {phi} x 20.5 cm{sup 2} polyethylene moderator, with a polyethylene pug where a {sup 197}Au foil can be located either parallel or perpendicular to moderator axis. Using Monte Carlo methods, with the MCNP5 code. With the fluence response and the fluence-to-equivalent dose conversion coefficients from ICRP-74, responses to H*(10) were also calculated, these were compared against responses of commercially available neutron area monitors and dosemeters. (Author)

  1. Evaluation of the nucledyne passive containment system

    International Nuclear Information System (INIS)

    1981-04-01

    This reports contains: (1) an evaluation by Gilbert/Commonwealth (G/C) of the NucleDyne passive Containment System (PCS) as that conceptual design is applied to a Westinghouse, two loop, Pressurized Water Reactor; (2) an evaluation by Westinghouse of two questions about the impact of the PCS on the Nuclear Steam Supply System (NSSS), which were posed by G/C and best answered by an NSSS vendor; and (3) replies to both the Gilbert/Commonwealth report and the Westinghoue report by NucleDyne Engineering Corporation

  2. Passive-solar: lessons from the past

    Energy Technology Data Exchange (ETDEWEB)

    Kennedy, R.

    The article reports on a research project conducted in Tunisia, in which ancient underground Roman homes in Bulla Reggia and similar inhabited Berber homes in Matmata were studied. Data were gathered on the passive-solar gain, compass orientations, and room measurements of the homes, and on natural lighting techniques, ventilation systems, earth-sheltered construction methods, cooling concepts, and domestic water collection systems used for these ancient dwellings. In addition, numerous sun-facing hill towns, cliff dwellings, and underground villages in Italy, France, and Spain were visited, with data recorded on window, shutter, and vent details, vegetation for climate control, and design concepts for climate-responsive town planning.

  3. Newnes passive and discrete circuits pocket book

    CERN Document Server

    MARSTON, R M

    2000-01-01

    Newnes Passive and Discrete Circuits Pocket Book is aimed at all engineers, technicians, students and experimenters who can build a design directly from a circuit diagram. In a highly concise form Ray Marston presents a huge compendium of circuits that can be built as they appear, adapted or used as building blocks. The devices used have been carefully chosen for their ease of availability and reasonable price. The selection of devices has been thoroughly updated for the second edition, which has also been expanded to cover the latest ICs.The three sections of the book cover: Moder

  4. Passive long range acousto-optic sensor

    Science.gov (United States)

    Slater, Dan

    2006-08-01

    Alexander Graham Bell's photophone of 1880 was a simple free space optical communication device that used the sun to illuminate a reflective acoustic diaphragm. A selenium photocell located 213 m (700 ft) away converted the acoustically modulated light beam back into sound. A variation of the photophone is presented here that uses naturally formed free space acousto-optic communications links to provide passive multichannel long range acoustic sensing. This system, called RAS (remote acoustic sensor), functions as a long range microphone with a demonstrated range in excess of 40 km (25 miles).

  5. Passive containment cooling water distribution device

    Science.gov (United States)

    Conway, Lawrence E.; Fanto, Susan V.

    1994-01-01

    A passive containment cooling system for a nuclear reactor containment vessel. Disclosed is a cooling water distribution system for introducing cooling water by gravity uniformly over the outer surface of a steel containment vessel using a series of radial guide elements and cascading weir boxes to collect and then distribute the cooling water into a series of distribution areas through a plurality of cascading weirs. The cooling water is then uniformly distributed over the curved surface by a plurality of weir notches in the face plate of the weir box.

  6. Hydrogen passivation of silicon sheet solar cells

    International Nuclear Information System (INIS)

    Tsuo, Y.S.; Milstein, J.B.

    1984-01-01

    Significant improvements in the efficiencies of dendritic web and edge-supported-pulling silicon sheet solar cells have been obtained after hydrogen ion beam passivation for a period of ten minutes or less. We have studied the effects of the hydrogen ion beam treatment with respect to silicon material damage, silicon sputter rate, introduction of impurities, and changes in reflectance. The silicon sputter rate for constant ion beam flux of 0.60 +- 0.05 mA/cm 2 exhibits a maximum at approximately 1400-eV ion beam energy

  7. Passive scalar transport in peripheral regions of random flows

    International Nuclear Information System (INIS)

    Chernykh, A.; Lebedev, V.

    2011-01-01

    We investigate statistical properties of the passive scalar mixing in random (turbulent) flows assuming its diffusion to be weak. Then at advanced stages of the passive scalar decay, its unmixed residue is primarily concentrated in a narrow diffusive layer near the wall and its transport to the bulk goes through the peripheral region (laminar sublayer of the flow). We conducted Lagrangian numerical simulations of the process for different space dimensions d and revealed structures responsible for the transport, which are passive scalar tongues pulled from the diffusive boundary layer to the bulk. We investigated statistical properties of the passive scalar and of the passive scalar integrated along the wall. Moments of both objects demonstrate scaling behavior outside the diffusive boundary layer. We propose an analytic scheme for the passive scalar statistics, explaining the features observed numerically.

  8. Some important issues in evaluating the availability of passive systems

    International Nuclear Information System (INIS)

    Kafka, P.; Kelemen, I.; Krzykacz, B.

    1993-01-01

    In some countries new reactor concepts based on a broader use of passive safety features are under development. The term 'passive' as used here refers to systems which rely heavily on natural heat transfer process such as natural circulation to perform their function rather than on decidedly 'active' components like pumps. The paper deals with important issues in evaluating the availability of passive systems, e.g. the assessment of the active components, the assessment of passive components and structures and the probabilistic assessment of the physical function of the natural processes. Based on an outlined assessment process for the entire system and on an exercised simulation process for the assessment of passive components e.g. pipes insights and important issues are presented. A follow-up study will refine and expand the concept to a full scope assessment procedure of passive systems. (author)

  9. Electromagnetic analysis of the passive stabilizers for EAST

    International Nuclear Information System (INIS)

    Du Shijun; Wang Liheng; Liu Xufeng; Yao Damao

    2006-01-01

    The electromagnetic problems of the passive stabilizers for EAST are analyzed in this paper. The eddy currents in the passive plates induced by vertical plasma motion converge at the edge of the plates. The time constant of the passive plates is relied on the eddy currents distribution and can be determined by analyzing the natural decay characteristic of eddy currents. The mutual inductance between the passive plates and the plasma can be found by calculating the flux in the plasma ring from the eddy currents. The distribution of electromagnetic loads acting on the passive plates is not uniform. As the poloidal eddy currents gather at the vertical connection conductors, the large normal electromagnetic forces caused by the stronger toroidal field and the poloidal currents concentrate at some regions of the passive plates

  10. Passivity-based control and estimation in networked robotics

    CERN Document Server

    Hatanaka, Takeshi; Fujita, Masayuki; Spong, Mark W

    2015-01-01

    Highlighting the control of networked robotic systems, this book synthesizes a unified passivity-based approach to an emerging cross-disciplinary subject. Thanks to this unified approach, readers can access various state-of-the-art research fields by studying only the background foundations associated with passivity. In addition to the theoretical results and techniques,  the authors provide experimental case studies on testbeds of robotic systems  including networked haptic devices, visual robotic systems,  robotic network systems and visual sensor network systems. The text begins with an introduction to passivity and passivity-based control together with the other foundations needed in this book. The main body of the book consists of three parts. The first examines how passivity can be utilized for bilateral teleoperation and demonstrates the inherent robustness of the passivity-based controller against communication delays. The second part emphasizes passivity’s usefulness for visual feedback control ...

  11. Preliminary investigation on reliability assessment of passive safety system

    International Nuclear Information System (INIS)

    Huang Changfan; Kuang Bo

    2012-01-01

    The reliability evaluation of passive safety system plays an important part in probabilistic safety assessment (PSA) of nuclear power plant applying passive safety design, which depends quantitatively on reliabilities of passive safety system. According to the object of reliability assessment of passive safety system, relevant parameters are identified. Then passive system behavior during accident scenarios are studied. A practical example of this method is given for the case of reliability assessment of AP1000 passive heat removal system in loss of normal feedwater accident. Key and design parameters of PRHRS are identified and functional failure criteria are established. Parameter combinations acquired by Latin hyper~ cube sampling (LHS) in possible parametric ranges are input and calculations of uncertainty propagation through RELAP5/MOD3 code are carried out. Based on the calculations, sensitivity assessment on PRHRS functional criteria and reliability evaluation of the system are presented, which might provide further PSA with PRHR system reliability. (authors)

  12. Enlightened Use of Passive Voice in Technical Writing

    Science.gov (United States)

    Trammell, M. K.

    1981-01-01

    The passive voice as a normal, acceptable, and established syntactic form in technical writing is defended. Passive/active verb ratios, taken from sources including 'antipassivist' text books, are considered. The suitability of the passive voice in technical writing which involves unknown or irrelevant agents is explored. Three 'myths' that the passive (1) utilizes an abnormal and artificial word order, (2) is lifeless, and (3) is indirect are considered. Awkward and abnormal sounding examples encountered in text books are addressed in terms of original context. Unattractive or incoherent passive sentences are explained in terms of inappropriate conversion from active sentences having (1) short nominal or pronominal subjects or (2) verbs with restrictions on their passive use.

  13. Surface passivation technology for III-V semiconductor nanoelectronics

    International Nuclear Information System (INIS)

    Hasegawa, Hideki; Akazawa, Masamichi

    2008-01-01

    The present status and key issues of surface passivation technology for III-V surfaces are discussed in view of applications to emerging novel III-V nanoelectronics. First, necessities of passivation and currently available surface passivation technologies for GaAs, InGaAs and AlGaAs are reviewed. Then, the principle of the Si interface control layer (ICL)-based passivation scheme by the authors' group is introduced and its basic characterization is presented. Ths Si ICL is a molecular beam epitaxy (MBE)-grown ultrathin Si layer inserted between III-V semiconductor and passivation dielectric. Finally, applications of the Si ICL method to passivation of GaAs nanowires and GaAs nanowire transistors and to realization of pinning-free high-k dielectric/GaAs MOS gate stacks are presented

  14. Anomalous scaling of passive scalars in rotating flows.

    Science.gov (United States)

    Rodriguez Imazio, P; Mininni, P D

    2011-06-01

    We present results of direct numerical simulations of passive scalar advection and diffusion in turbulent rotating flows. Scaling laws and the development of anisotropy are studied in spectral space, and in real space using an axisymmetric decomposition of velocity and passive scalar structure functions. The passive scalar is more anisotropic than the velocity field, and its power spectrum follows a spectral law consistent with ~ k[Please see text](-3/2). This scaling is explained with phenomenological arguments that consider the effect of rotation. Intermittency is characterized using scaling exponents and probability density functions of velocity and passive scalar increments. In the presence of rotation, intermittency in the velocity field decreases more noticeably than in the passive scalar. The scaling exponents show good agreement with Kraichnan's prediction for passive scalar intermittency in two dimensions, after correcting for the observed scaling of the second-order exponent.

  15. Repeated passive stretching : Acute effect on the passive muscle moment and extensibility of short hamstrings

    NARCIS (Netherlands)

    Halbertsma, JPK; Mulder, [No Value; Goeken, LNH; Eisma, WH; Mulder, I.; Göeken, L.N.

    Objective: To examine the response of short hamstring muscles to repeated passive stretching. Design: A repeated measures design. Setting: A university laboratory for human movement analysis in a department of rehabilitation. Subjects: Students (7 men, 10 women) from the Department of Human Movement

  16. Un « gouvernement des journalistes par le Pouvoir politique » par défaut ?

    Directory of Open Access Journals (Sweden)

    Matthieu Lardeau

    2013-12-01

    Full Text Available Cet article présente les interactions de deux mouvements concomitants apparusprincipalement dans les décennies 1950 à 1970 dans le champ de la presse française : d’un côté les initiatives – consécutives à la démarche pionnière, en 1951, de création de la première Société des journalistes (SDJ au sein du Monde – menées par les journalistes de rédactions de quotidiens pour créer des SDJ dont la destination peut aller jusqu’à gouverner les journaux; de l’autre côté, les « réponses » apportées par les Pouvoirs politique et public pour contenir ces initiatives visant à étendre le pouvoir des journalistes dans la gestion et la gouvernance de leurs journaux. Cette étude exploratoire repose principalement sur l’analyse de deux types de littérature, souvent déconsidérés ou négligés par le champ académique, en dépit de leur grande richesse : (1 la littérature professionnelle, ayant pour principaux auteurs les journalistes et managers de presse (Périer Daville, Boegner, Pigasse, etc., florissante depuis 1944 et singulièrement durant les décennies 1960 et 1970 ; (2 la littérature grise constituée notamment par des rapports publics rédigés par des institutions comme les services du Premier ministre (commissions Lindon de 1970 et Serisé de 1972, le Conseil économique et social, etc. Nos principaux résultats montrent que les propositions ou actions menées par les journalistes (1 restent le plus souvent inexploitées in concreto par les journalistes eux-mêmes; (2 entrent le plus souvent en opposition avec les politiques de nouveaux actionnaires ou directions de journaux et avec les projets des autorités politiques et publiques qui cherchent à encadrer l’autonomie de la profession journalistique pour mieux gouverner celle-ci ; (3 combien in fine les représentants des différents acteurs impliqués s’accordent pour contenir l’émergence d’un « gouvernement des journalistes » par les

  17. Approach to interior design for passive direct gain solar homes

    Energy Technology Data Exchange (ETDEWEB)

    Kachadorian, C.C.

    1980-01-01

    In response to requests from buyers and builders of direct gain passive solar homes interior design criteria either specific to, or emphasized by, passive solar buildings are investigated. Problems of high sunlight penetration, secondary illumination, material selection, sound control and psychology are approached. Material deterioration, fading, glare, noise, and a sense of spacial confinement can be minimized, contributing to the appeal and saleability of passive solar homes.

  18. Passive and Active Observation: Experimental Design Issues in Big Data

    OpenAIRE

    Pesce, Elena; Riccomagno, Eva; Wynn, Henry P.

    2017-01-01

    Data can be collected in scientific studies via a controlled experiment or passive observation. Big data is often collected in a passive way, e.g. from social media. Understanding the difference between active and passive observation is critical to the analysis. For example in studies of causation great efforts are made to guard against hidden confounders or feedback which can destroy the identification of causation by corrupting or omitting counterfactuals (controls). Various solutions of th...

  19. Passive safety and the advanced liquid metal reactors

    International Nuclear Information System (INIS)

    Hill, D.J.; Pedersen, D.R.; Marchaterre, J.F.

    1988-01-01

    Advanced Liquid Metal Reactors being developed today in the USA are designed to make maximum use of passive safety features. Much of the LMR safety work at Argonne National Laboratory is concerned with demonstrating, both theoretically and experimentally, the effectiveness of the passive safety features. The characteristics that contribute to passive safety are discussed, with particular emphasis on decay heat removal systems, together with examples of Argonne's theoretical and experimental programs in this area

  20. Innovative Facet Passivation for High-Brightness Laser Diodes

    Science.gov (United States)

    2016-02-05

    processing will prevent oxidation of the front facet, the leading contaminant from the ambient. By keeping the MBE growth temperatures between 400 and 500 ...suitably adjusted Al mole fraction and growth recipes . Specifically, MBE-AlGaAs passivation can apply to slab pumped lasers (e.g. 808 nm), fiber...li ty OHMIC CONTACTS PASSIVATION LAYER 400 OC 500 OC THERMAL “ SWEET SPOT ” POLYCRYTALLINE / LATTICE MIS-MATCHED PASSIVATION OHMIC CONTACT DEGRADATION

  1. Westinghouse Advances in Passive Plant Safety

    International Nuclear Information System (INIS)

    Bruschi, H. J.; Manager, General; Gerstenhaber, E.

    1993-01-01

    On June 26, 1992, Westinghouse submitted the Ap600 Standard Safety Analysis Report and comprehensive PIRA results to the U. S. NRC for review as part of the Ap600 design certification program. This major milestone was met on time on a schedule set more than 3 years before submittal and is the result of the cooperative efforts of the U. S. Department of Energy (DOE), the Electric Power Requirements Program, and the Westinghouse Ap600 design team. These efforts were initiated in 1985 to develop a 600 MW advanced light water reactor plant design based on specific technical requirements established to provide the safety, simplicity, reliability, and economics necessary for the next generation of nuclear power plants. The Ap600 design achieves the ALRR safety requirements through ample design margins, simplified safety systems based on natural driving forces, and on a human-engineered man-machine interface system. Extensive Probabilistic Risk evolution, have recently shown that even if none of the active defense-in-depth safety systems are available, the passive systems alone meet safety goals. Furthermore, many tests in an extensive test program have begun or have been completed. Early tests show that passive safety perform well and meet design expectations

  2. Passive solar energy information user study

    Energy Technology Data Exchange (ETDEWEB)

    Belew, W.W.; Wood, B.L.; Marle, T.L.; Reinhardt, C.L.

    1980-11-01

    The results of a series of telephone interviews with groups of users of information on passive solar heating and cooling are described. These results, part of a larger study on many different solar technologies, identify types of information each group needed and the best ways to get information to each group. The overall study provides baseline data about information needs in the solar community. An earlier study identified the information user groups in the solar community and the priority (to accelerate solar energy commercialization) of getting information to each group. In the current study only high-priority groups were examined. Results from seven passive groups respondents are analyzed in this report: Federally Funded Researchers, Manufacturer Representatives, Architects, Builders, Educators, Cooperative Extension Service County Agents, and Homeowners. The data will be used as input to the determination of information products and services the Solar Energy Research Institute, the Solar Energy Information Data Bank Network, and the entire information outreach community should be preparing and disseminating.

  3. Beskyttelse mod passiv rygning i botilbud

    DEFF Research Database (Denmark)

    Faber, Louise

    2018-01-01

    ikke tidligere har været forbud. Denne problemstilling er aktuelt lige nu i forhold til passiv rygning, der tolereres mindre end tidligere. I denne artikel undersøges, i hvilket omfang der er mulighed for, at udstede rygeforbud på botilbud, når formålet med forbuddet er at beskytte andre beboere mod......Myndigheder har pligt til at beskytte individer mod ufrivillig sundhedsskadelig påvirkning i medfør af EMRK art. 8, stk. 1. På områder, hvor individets tolerancetærskel for sundhedsskadelig påvirkning bliver mindre end tidligere, kan der opstå behov for at udstede forbud i situationer, hvor der...... ufrivillig passiv rygning. Problemstilingen belyses i en forvaltningsretlig kontekst med udgangspunkt i dansk ret. Forfatteren konkluderer, at der er hjemmel i den danske Lov om Røgfrie Miljøer til at forbyde rygning, men at reglerne ikke giver tilstrækkelig beskyttelse i den situation, hvor en beboer...

  4. Improvement of passive THz camera images

    Science.gov (United States)

    Kowalski, Marcin; Piszczek, Marek; Palka, Norbert; Szustakowski, Mieczyslaw

    2012-10-01

    Terahertz technology is one of emerging technologies that has a potential to change our life. There are a lot of attractive applications in fields like security, astronomy, biology and medicine. Until recent years, terahertz (THz) waves were an undiscovered, or most importantly, an unexploited area of electromagnetic spectrum. The reasons of this fact were difficulties in generation and detection of THz waves. Recent advances in hardware technology have started to open up the field to new applications such as THz imaging. The THz waves can penetrate through various materials. However, automated processing of THz images can be challenging. The THz frequency band is specially suited for clothes penetration because this radiation does not point any harmful ionizing effects thus it is safe for human beings. Strong technology development in this band have sparked with few interesting devices. Even if the development of THz cameras is an emerging topic, commercially available passive cameras still offer images of poor quality mainly because of its low resolution and low detectors sensitivity. Therefore, THz image processing is very challenging and urgent topic. Digital THz image processing is a really promising and cost-effective way for demanding security and defense applications. In the article we demonstrate the results of image quality enhancement and image fusion of images captured by a commercially available passive THz camera by means of various combined methods. Our research is focused on dangerous objects detection - guns, knives and bombs hidden under some popular types of clothing.

  5. The polarity protein Par6 is coupled to the microtubule network during molluscan early embryogenesis

    Energy Technology Data Exchange (ETDEWEB)

    Homma, Taihei [Department of Biophysics and Biochemistry, Graduate School of Science, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan); Shimizu, Miho [Kuroda Chiromorphology Team, ERATO-SORST, JST, Komaba, Meguro-ku, Tokyo 153-8902 (Japan); Kuroda, Reiko, E-mail: ckuroda@mail.ecc.u-tokyo.ac.jp [Department of Biophysics and Biochemistry, Graduate School of Science, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan); Kuroda Chiromorphology Team, ERATO-SORST, JST, Komaba, Meguro-ku, Tokyo 153-8902 (Japan); Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Komaba, Meguro-ku, Tokyo 153-8902 (Japan)

    2011-01-07

    Research highlights: {yields} The cDNAs encoding Par6 and aPKC homologues were cloned from the snail Lymnaea stagnalis. {yields} L. stagnalis Par6 directly interacts with tubulin and microtubules and localizes to the microtubule cytoskeleton during the early embryogenesis. {yields} Identical sequence and localization of LsPar6 for the dextral and the sinistral snails exclude the possibility of the gene being the primary determinant of body handedness. -- Abstract: Cell polarity, which directs the orientation of asymmetric cell division and segregation of fate determinants, is a fundamental feature of development and differentiation. Regulators of polarity have been extensively studied, and the critical importance of the Par (partitioning-defective) complex as the polarity machinery is now recognized in a wide range of eukaryotic systems. The Par polarity module is evolutionarily conserved, but its mechanism and cooperating factors vary among different systems. Here we describe the cloning and characterization of a pond snail Lymnaea stagnalis homologue of partitioning-defective 6 (Lspar6). The protein product LsPar6 shows high affinity for microtubules and localizes to the mitotic apparatus during embryonic cell division. In vitro assays revealed direct binding of LsPar6 to tubulin and microtubules, which is the first evidence of the direct interaction between the two proteins. The interaction is mediated by two distinct regions of LsPar6 both located in the N-terminal half. Atypical PKC, a functional partner of Par6, was also found to localize to the mitotic spindle. These results suggest that the L. stagnalis Par complex employs the microtubule network in cell polarity processes during the early embryogenesis. Identical sequence and localization of LsPar6 for the dextral and the sinistral snails exclude the possibility of the gene being the primary determinant of handedness.

  6. The polarity protein Par6 is coupled to the microtubule network during molluscan early embryogenesis

    International Nuclear Information System (INIS)

    Homma, Taihei; Shimizu, Miho; Kuroda, Reiko

    2011-01-01

    Research highlights: → The cDNAs encoding Par6 and aPKC homologues were cloned from the snail Lymnaea stagnalis. → L. stagnalis Par6 directly interacts with tubulin and microtubules and localizes to the microtubule cytoskeleton during the early embryogenesis. → Identical sequence and localization of LsPar6 for the dextral and the sinistral snails exclude the possibility of the gene being the primary determinant of body handedness. -- Abstract: Cell polarity, which directs the orientation of asymmetric cell division and segregation of fate determinants, is a fundamental feature of development and differentiation. Regulators of polarity have been extensively studied, and the critical importance of the Par (partitioning-defective) complex as the polarity machinery is now recognized in a wide range of eukaryotic systems. The Par polarity module is evolutionarily conserved, but its mechanism and cooperating factors vary among different systems. Here we describe the cloning and characterization of a pond snail Lymnaea stagnalis homologue of partitioning-defective 6 (Lspar6). The protein product LsPar6 shows high affinity for microtubules and localizes to the mitotic apparatus during embryonic cell division. In vitro assays revealed direct binding of LsPar6 to tubulin and microtubules, which is the first evidence of the direct interaction between the two proteins. The interaction is mediated by two distinct regions of LsPar6 both located in the N-terminal half. Atypical PKC, a functional partner of Par6, was also found to localize to the mitotic spindle. These results suggest that the L. stagnalis Par complex employs the microtubule network in cell polarity processes during the early embryogenesis. Identical sequence and localization of LsPar6 for the dextral and the sinistral snails exclude the possibility of the gene being the primary determinant of handedness.

  7. Paternal age related schizophrenia (PARS): Latent subgroups detected by k-means clustering analysis.

    Science.gov (United States)

    Lee, Hyejoo; Malaspina, Dolores; Ahn, Hongshik; Perrin, Mary; Opler, Mark G; Kleinhaus, Karine; Harlap, Susan; Goetz, Raymond; Antonius, Daniel

    2011-05-01

    Paternal age related schizophrenia (PARS) has been proposed as a subgroup of schizophrenia with distinct etiology, pathophysiology and symptoms. This study uses a k-means clustering analysis approach to generate hypotheses about differences between PARS and other cases of schizophrenia. We studied PARS (operationally defined as not having any family history of schizophrenia among first and second-degree relatives and fathers' age at birth ≥ 35 years) in a series of schizophrenia cases recruited from a research unit. Data were available on demographic variables, symptoms (Positive and Negative Syndrome Scale; PANSS), cognitive tests (Wechsler Adult Intelligence Scale-Revised; WAIS-R) and olfaction (University of Pennsylvania Smell Identification Test; UPSIT). We conducted a series of k-means clustering analyses to identify clusters of cases containing high concentrations of PARS. Two analyses generated clusters with high concentrations of PARS cases. The first analysis (N=136; PARS=34) revealed a cluster containing 83% PARS cases, in which the patients showed a significant discrepancy between verbal and performance intelligence. The mean paternal and maternal ages were 41 and 33, respectively. The second analysis (N=123; PARS=30) revealed a cluster containing 71% PARS cases, of which 93% were females; the mean age of onset of psychosis, at 17.2, was significantly early. These results strengthen the evidence that PARS cases differ from other patients with schizophrenia. Hypothesis-generating findings suggest that features of PARS may include a discrepancy between verbal and performance intelligence, and in females, an early age of onset. These findings provide a rationale for separating these phenotypes from others in future clinical, genetic and pathophysiologic studies of schizophrenia and in considering responses to treatment. Copyright © 2011 Elsevier B.V. All rights reserved.

  8. EP 1000 -The European Passive Plant

    International Nuclear Information System (INIS)

    Cummins, Ed; Oyarzabal, Mariano; Saiu, Gianfranco

    1998-01-01

    A group of European utilities, along with Westinghouse and its industrial partner GENESI (an Italian consortium including ANSALDO and FIAT) initiated a program to evaluate Westinghouse passive nuclear plant technology for application in Europe. The European utility group consisted of: Agrupacion electrica para al Desarrollo Technologico Nuclear (DTN), Spain; Electricite de France; ENEL, SpA., Italy; IVO Power Engineering, Ltd., Finland; Scottish Nuclear Limited (acting for itself on behalf of Nuclear Electric plc, U.K.; Tractebel Energy Engineering, Belgium; UAK (represented by NOK-Beznau), Switzerland; and Vattenfall AB, Ringhals, Sweden. The European Passive Plant (EPP) program, which began in 1994, is an evaluation of the Westinghouse 600 MWe AP 600 and 1000 MWe Simplified Pressurized Water Reactor (SPWR) designs in meeting the European Utility Requirements (EUR), and where necessary, modifying the design to achieve compliance. Phase 1 or the EPP program was completed and included the two major tasks of evaluating the effect of the EUR on the Westinghouse nuclear island and developing the EP 1000, a 1000 MWe passive plant reference design that conforms to the EUR and would be licensable in Europe. The EP 1000 closely follows the Westinghouse SPWR design for safety systems and containment and the AP 600 design for auxiliary systems. It also includes features that where required to meet the EUR and key European licensing requirements. The primary circuit of the EP 1000 retains most of the general features of the current-day designs, but some evolutionary features to enhance reliability, simplicity of operation, ease of maintenance, and plant safety have been incorporated into the design. The core, reactor vessel, and reactor internals of the EP 1000 are similar to those of currently operating Westinghouse PWR plants, but several new features are included to enhance the performance characteristics. The basic EP 1000 safety philosophy is based on use of inherent

  9. Imparting passivity to vapor deposited magnesium alloys

    Science.gov (United States)

    Wolfe, Ryan C.

    Magnesium has the lowest density of all structural metals. Utilization of low density materials is advantageous from a design standpoint, because lower weight translates into improved performance of engineered products (i.e., notebook computers are more portable, vehicles achieve better gas mileage, and aircraft can carry more payload). Despite their low density and high strength to weight ratio, however, the widespread implementation of magnesium alloys is currently hindered by their relatively poor corrosion resistance. The objective of this research dissertation is to develop a scientific basis for the creation of a corrosion resistant magnesium alloy. The corrosion resistance of magnesium alloys is affected by several interrelated factors. Among these are alloying, microstructure, impurities, galvanic corrosion effects, and service conditions, among others. Alloying and modification of the microstructure are primary approaches to controlling corrosion. Furthermore, nonequilibrium alloying of magnesium via physical vapor deposition allows for the formation of single-phase magnesium alloys with supersaturated concentrations of passivity-enhancing elements. The microstructure and surface morphology is also modifiable during physical vapor deposition through the variation of evaporation power, pressure, temperature, ion bombardment, and the source-to-substrate distance. Aluminum, titanium, yttrium, and zirconium were initially chosen as candidates likely to impart passivity on vapor deposited magnesium alloys. Prior to this research, alloys of this type have never before been produced, much less studied. All of these metals were observed to afford some degree of corrosion resistance to magnesium. Due to the especially promising results from nonequilibrium alloying of magnesium with yttrium and titanium, the ternary magnesium-yttrium-titanium system was investigated in depth. While all of the alloys are lustrous, surface morphology is observed under the scanning

  10. Electron microscope study of vacancy clusters produced by quenching in magnesium; Etude par microscopie electronique des amas de lacunes crees par trempe dans le magnesium

    Energy Technology Data Exchange (ETDEWEB)

    Levy, V; Espinasse, J; Mairy, C; Hillairet, J [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1969-07-01

    Vacancy clustering in quenched magnesium has been studied by transmission electron microscopy. The nature of the vacancy loops observed, seems to depend essentially on the impurity content of the metal; this effect can be attributed to a variation of the stacking fault energy of magnesium due to impurities. (authors) [French] On a etudie par microscopie electronique en transmission les defauts crees par trempe dans le magnesium. Un effet considerable des impuretes du metal sur la nature des boucles obtenues par condensation de lacunes a ete mis en evidence; cet effet semble s'expliquer de facon satisfaisante par un abaissement de l'energie de faute d'empilement du magnesium du aux impuretes. (auteur)

  11. Photoluminescence model of sulfur passivated p-InP nanowires

    International Nuclear Information System (INIS)

    Tajik, N; Haapamaki, C M; LaPierre, R R

    2012-01-01

    The effect of ammonium polysulfide solution, (NH 4 ) 2 S x , on the surface passivation of p-doped InP nanowires (NWs) was investigated by micro-photoluminescence. An improvement in photoluminescence (PL) intensity from individual NWs upon passivation was used to optimize the passivation procedure using different solvents, sulfur concentrations and durations of passivation. The optimized passivation procedure gave an average of 24 times improvement in peak PL intensity. A numerical model is presented to explain the PL improvement upon passivation in terms of a reduction in surface trap density by two orders of magnitude from 10 12 to 10 10 cm −2 , corresponding to a change in surface recombination velocity from 10 6 to 10 4 cm s −1 . The diameter dependence of the PL intensity is investigated and explained by the model. The PL intensity from passivated nanowires decreased to its initial (pre-passivation) value over a period of seven days in ambient air, indicating that the S passivation was unstable. (paper)

  12. Extrinsic passivation of silicon surfaces for solar cells

    OpenAIRE

    Bonilla, R.S.; Reichel, C.; Hermle, M.; Martins, G.; Wilshaw, P.R.

    2015-01-01

    In the present work we study the extent to which extrinsic chemical and field effect passivation can improve the overall electrical passivation quality of silicon dioxide on silicon. Here we demonstrate that, when optimally applied, extrinsic passivation can produce surface recombination velocities below 1.2 cm/s in planar 1 Omega cm n-type Si. This is largely due to the additional field effect passivation component which reduces the recombination velocity below 2.13 cm/s. On textured surface...

  13. European Embedding of Passive Houses. www.europeanpassivehouses.org

    Energy Technology Data Exchange (ETDEWEB)

    Elswijk, M.; Kaan, H. (eds.) [and others

    2008-05-15

    The passive house concept has become a European wide accepted solution to reach a significant energy demand reduction in the built environment. The European Commission has published the ambition to construct newly built ho uses in 2015 accordingly to the passive ho use standard. In most project participating countries this ambition is shared. With the support of the Intelligent Energy Europe program this project 'Promotion of European Passive Houses' (PEP-project) contributed to achieve this ambition to clear the first market barriers internationally to reach the status 'Business As Usual' for passive houses in 2015. The PEP project aimed at the development of easy accessible web based documentation for stakeholders in the building process to solve national market introduction barriers regarding the passive house concept. The project also aimed at the distribution of this information via international and national workshops, seminars and conferences. It can be concluded that the PEP-project has been successful. All participating countries made significant progress in the societal embedding process of passive houses and in most countries the passive house concept is on the brink of breaking through nationally. Further, the PEP-project contributed successfully in the internationalisation of the Internal Passive House Conference and fixed the definition of a passive house for three geographical European regions. Finally, the PEP website with its wealth of information was a powerful tool for promotion of passive houses in Europe. In order to increase the implementation efficiency of the passive house concept it is recommended to develop additional information packages concerning passive house solutions for offices, schools and social homes (e.g. architectural examples, organisational issues); passive house renovations; financial schemes for passive houses; performance oriented quality approach for the design and construction process; industrial

  14. Demonstration of Passive Fuel Cell Thermal Management Technology

    Science.gov (United States)

    Burke, Kenneth A.; Jakupca, Ian; Colozza, Anthony; Wynne, Robert; Miller, Michael; Meyer, Al; Smith, William

    2012-01-01

    The NASA Glenn Research Center is developing advanced passive thermal management technology to reduce the mass and improve the reliability of space fuel cell systems for the NASA Exploration program. The passive thermal management system relies on heat conduction within highly thermally conductive cooling plates to move the heat from the central portion of the cell stack out to the edges of the fuel cell stack. Using the passive approach eliminates the need for a coolant pump and other cooling loop components within the fuel cell system which reduces mass and improves overall system reliability. Previous development demonstrated the performance of suitable highly thermally conductive cooling plates and integrated heat exchanger technology to collect the heat from the cooling plates (Ref. 1). The next step in the development of this passive thermal approach was the demonstration of the control of the heat removal process and the demonstration of the passive thermal control technology in actual fuel cell stacks. Tests were run with a simulated fuel cell stack passive thermal management system outfitted with passive cooling plates, an integrated heat exchanger and two types of cooling flow control valves. The tests were run to demonstrate the controllability of the passive thermal control approach. Finally, successful demonstrations of passive thermal control technology were conducted with fuel cell stacks from two fuel cell stack vendors.

  15. Towards an Effective Management Strategy for Passive RFID Implementation

    National Research Council Canada - National Science Library

    Fisch, John N; Koch, David M

    2004-01-01

    .... However, many issues central to passive RFID implementation remain unresolved. First and foremost, a comprehensive management strategy, including a complete redesign of business practices, must be developed...

  16. An investigation of a passively controlled haptic interface

    Energy Technology Data Exchange (ETDEWEB)

    Davis, J.T. [Oak Ridge National Lab., TN (United States); Book, W.J. [Georgia Inst. of Tech., Atlanta, GA (United States). School of Mechanical Engineering

    1997-03-01

    Haptic interfaces enhance cooperation between humans and robotic manipulators by providing force and tactile feedback to the human user during the execution of arbitrary tasks. The use of active actuators in haptic displays presents a certain amount of risk since they are capable of providing unacceptable levels of energy to the systems upon which they operate. An alternative to providing numerous safeguards is to remove the sources of risk altogether. This research investigates the feasibility of trajectory control using passive devices, that is, devices that cannot add energy to the system. Passive actuators are capable only of removing energy from the system or transferring energy within the system. It is proposed that the utility of passive devices is greatly enhanced by the use of redundant actuators. In a passive system, once motion is provided to the system, presumably by a human user, passive devices may be able to modify this motion to achieve a desired resultant trajectory. A mechanically passive, 2-Degree-of-Freedom (D.O.F.) manipulator has been designed and built. It is equipped with four passive actuators: two electromagnetic brakes and two electromagnetic clutches. This paper gives a review of the literature on passive and robotics and describes the experimental test bed used in this research. Several control algorithms are investigated, resulting in the formulation of a passive control law.

  17. Passive RF component technology materials, techniques, and applications

    CERN Document Server

    Wang, Guoan

    2012-01-01

    Focusing on novel materials and techniques, this pioneering volume provides you with a solid understanding of the design and fabrication of smart RF passive components. You find comprehensive details on LCP, metal materials, ferrite materials, nano materials, high aspect ratio enabled materials, green materials for RFID, and silicon micromachining techniques. Moreover, this practical book offers expert guidance on how to apply these materials and techniques to design a wide range of cutting-edge RF passive components, from MEMS switch based tunable passives and 3D passives, to metamaterial-bas

  18. Performance of the PBX-M passive plate stabilization system

    International Nuclear Information System (INIS)

    Kugel, H.W.; Bell, R.; Bernabei, S.

    1994-02-01

    The PBX-M passive plate stabilization system provides significant stabilization of long-wavelength external kink modes, the slowing of vertical instability growth rates, and the amelioration of disruption characteristics. The passive plate stabilization system has allowed the use of LHCD and IBW to induce current density and pressure profile modifications, and m = 1 divertor biasing for modifying edge plasma transport. Improvements in the passive plate system insulators and support structures have provided reliable operation. Impurity influxes with the close-fitting passive plates are low. Solid target boronization is applied routinely to reduce conditioning time and maintain clean conditions

  19. Development of IAEA description of passive safety and subsequent thoughts

    Energy Technology Data Exchange (ETDEWEB)

    Lang, P M [USDOE, Washington, DC (United States)

    1996-12-01

    The description of passive components and systems published by the IAEA in its TECDOC-626 was developed in the course of a Technical Committee Meeting held in Sweden and two subsequent Consultants Meetings held in Vienna. This description is reviewed and discussed in terms of the philosophies behind it, alternatives considered, problems encountered, and conclusions drawn. Also discussed is an Appendix to the TECDOC, which illustrates the spectrum of possibilities from passive to active by describing four typical categories of passivity. Subsequent thoughts on passive safety include a discussion of its advantages and disadvantages, concluding with a summary of current views and problems with it. (author). 8 refs.

  20. An investigation of a passively controlled haptic interface

    International Nuclear Information System (INIS)

    Davis, J.T.; Book, W.J.

    1997-01-01

    Haptic interfaces enhance cooperation between humans and robotic manipulators by providing force and tactile feedback to the human user during the execution of arbitrary tasks. The use of active actuators in haptic displays presents a certain amount of risk since they are capable of providing unacceptable levels of energy to the systems upon which they operate. An alternative to providing numerous safeguards is to remove the sources of risk altogether. This research investigates the feasibility of trajectory control using passive devices, that is, devices that cannot add energy to the system. Passive actuators are capable only of removing energy from the system or transferring energy within the system. It is proposed that the utility of passive devices is greatly enhanced by the use of redundant actuators. In a passive system, once motion is provided to the system, presumably by a human user, passive devices may be able to modify this motion to achieve a desired resultant trajectory. A mechanically passive, 2-Degree-of-Freedom (D.O.F.) manipulator has been designed and built. It is equipped with four passive actuators: two electromagnetic brakes and two electromagnetic clutches. This paper gives a review of the literature on passive and robotics and describes the experimental test bed used in this research. Several control algorithms are investigated, resulting in the formulation of a passive control law

  1. Passive autocatalytic recombiner process features and new status of international qualification

    International Nuclear Information System (INIS)

    Eckardt, Bernd A.; Losch, Norbert

    2010-01-01

    New results of International PAR-Severe Accidents Qualification in frame of EC/IRSN Core Melt Program PHEBUS (with real molten core) are presented. Example Results: AREVA PAR Design: Best performance very fast start-up • highest efficiency absolutely constant hydrogen depletion rates. Others: Some industrial competitors failed. This enveloping real severe accident tests represents the new international PAR qualification standard and finalized the PAR qualification successfully. The design features supports PAR Dual function

  2. Neutrons detection by scintillation; Detection de neutrons par scintillations

    Energy Technology Data Exchange (ETDEWEB)

    Giraudon, J [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1955-01-15

    The absence of charge of neutrons and their elevated penetration power make difficult their detection. Techniques vary otherwise with the energy of the particle. The author proposes the realization of a scintillation detector with a big volume of liquid scintillator and containing boron for the detection of slowing-down neutrons in the domain of intermediate energies from 1 to 10{sup 5} eV about. (M.B.) [French] L'absence de charge du neutron et son pouvoir de penetration eleve rendent difficile sa detection. Les techniques par ailleurs varient avec l'energie de cette particule. L'auteur propose la realisation d'un detecteur a scintillations comprenant un grand volume de scintillateur liquide et contenant du bore pour la detection des neutrons en ralentissement dans le domaine des energies intermediaires de 1 a 10{sup 5} eV environ. (M.B.)

  3. Cancro em mogno africano no estado do Pará

    Directory of Open Access Journals (Sweden)

    Célia Regina Tremacoldi

    2013-06-01

    Full Text Available Sintomas de cancro foram observados em plantios de mogno africano, no município de Dom Eliseu, Pará. Os fungos associados aos tecidos sintomáticos foram identificados como Lasiodiplodia theobromae e Fusarium subglutinans. Culturas puras desses fungos foram testadas quanto à patogenicidade em mudas de mogno africano sadias. Apenas L. theobromae produziu cancro, por meio de inoculação por ferimento e alta umidade. A confirmação de L. theobromae como agente causal do cancro ocorreu após o reisolamento do fungo a partir das plantas inoculadas em casa de vegetação, concluindo a primeira verificação do postulado de Koch para esse patossistema.

  4. IMPROVEMENT OF PRODUCTION PLANNING IN COMPANY PARS KOMPONENTY

    Directory of Open Access Journals (Sweden)

    René Klega

    2014-03-01

    Full Text Available The article analyzes the current status of production planning in company Pars Komponenty s.r.o., proposes a new method of planning based on application of the principle of MRP. It is a discrete type of production with high complexity of BOM and MTO (Make-to-Order and ETO (Engineering-to-Order from the point of decoupling point. The original planning system plans according to production capacity backward without collisions, but for a given type of production does not work in practice. Planning system was analyzed and the main problems were identified, which were high work in progress and material stocks. This article target is to propose a new planining system based on the inclusion of time reserves of purchased material items. New planning system was tested in practise with benefit in reducing both the material inventory and work in progress.

  5. Pierre Vilar Frontinhan 1906 - París 2003

    Directory of Open Access Journals (Sweden)

    Pablo Rodríguez

    2003-01-01

    Full Text Available En el pasado mes de agosto falleció en París el historiador y maestro de tantas generaciones Pierre Vilar. Aunque había mantenido una intensa actividad de reflexión sobre los sucesos contemporáneos, ésta se vio afectada en 1991 luego que una grave enfermedad le negó la visión. Fue entonces cuando decidió con la ayuda de Rosa Congost escribir sus reflexiones y recuerdos, especie de memoria de juventud. Pensar Históricamente (Barcelona: Editorial Crítica, 1997, el libro que reúne estos ejercicios, es una obra de sumo interés para conocer la infancia, adolescencia y juventud de este connotado historiador.

  6. Neutrons detection by scintillation; Detection de neutrons par scintillations

    Energy Technology Data Exchange (ETDEWEB)

    Giraudon, J. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1955-01-15

    The absence of charge of neutrons and their elevated penetration power make difficult their detection. Techniques vary otherwise with the energy of the particle. The author proposes the realization of a scintillation detector with a big volume of liquid scintillator and containing boron for the detection of slowing-down neutrons in the domain of intermediate energies from 1 to 10{sup 5} eV about. (M.B.) [French] L'absence de charge du neutron et son pouvoir de penetration eleve rendent difficile sa detection. Les techniques par ailleurs varient avec l'energie de cette particule. L'auteur propose la realisation d'un detecteur a scintillations comprenant un grand volume de scintillateur liquide et contenant du bore pour la detection des neutrons en ralentissement dans le domaine des energies intermediaires de 1 a 10{sup 5} eV environ. (M.B.)

  7. Determination of tritium by counting; Dosage du tritium par comptage

    Energy Technology Data Exchange (ETDEWEB)

    Schott, R; Froment, G; Pinson, J; Genty, C [Commissariat a l' Energie Atomique, Bruyeres-le-Chatel (France). Centre d' Etudes

    1968-07-01

    Ionisation chamber assay of tritium in any gaseous mixture is a simple, fast and accurate method. We used the method of relative determination by comparison to a standard rather than the method of absolute assay in which case the constants are known with too little accuracy. The efficiency of the chamber was studied in connection to the pressure inside the chamber and its total volume. The calibration is linear in the range we are taking into account (1 to 80 millicuries). The reproducibility of the method is good: 13 runs gave a coefficient of variation of 1.6 per cent. The relative accuracy was found equal to {+-} 1.3 per cent. To end the paper, we describe in detail the apparatus and the ways of proceedings. (authors) [French] Le comptage du tritium par chambre d'ionisation est une methode simple, rapide et precise pour determiner la teneur en tritium d'un melange gazeux quelconque. Nous avons prefere utiliser la methode de determination relative par rapport a un etalon car, dans le cas d'une determination absolue, les constantes sont connues avec une trop grande incertitude. L'efficacite de la chambre a ete etudiee en fonction de la variation de la pression d'argon a l'interieur de la chambre et du volume total, de cette derniere. L'etalonnage s'est revele lineaire dans le domaine de mesures qui nous interessaient (1 a 80 millicuries). La reproductibillte de la methode est tres bonne, le coefficient de variation pour une serie de 13 essais etant de 1,6 pour cent, quant a la precision relative, elle a ete evaluee a {+-} 1,3 pour cent. Pour terminer, nous donnons une description detaillee de l'appareillage utilise et du mode operatoire suivi. (auteurs)

  8. Clinical outcomes of pars plicata anterior vitrectomy: 2-year results

    Directory of Open Access Journals (Sweden)

    Priya Narang

    2015-01-01

    Full Text Available Purpose: To demonstrate the safety and outcome of a surgical approach that uses pars plicata site for anterior vitrectomy during phacoemulsification procedure complicated by posterior capsule rupture and residual cortical matter. Design: Single center, retrospective, interventional, noncomparative study. Materials and Methods: Medical records of a consecutive series of 35 eyes of 35 patients who underwent pars plicata anterior vitrectomy (PPAV were reviewed. The main outcome measures were corrected and uncorrected distance visual acuity (CDVA, UDVA, early and late postoperative complications and intraocular pressure (IOP. Ultrasound biomicroscopic (UBM evaluation of sclerotomy site and spectral domain optical coherence tomography analysis for central macular thickness (CMT was performed. The final visual outcome at 2 years was evaluated. Results: At 2 years follow-up, the mean postoperative UDVA (logarithm of the minimum angle of resolution [logMAR] and CDVA (logMAR was 0.49 ± 0.26 and 0.19 ± 0.14, respectively. There was no significant change in the IOP (P = 0.061 and the mean CMT at 2 years was 192.5 ± 5.54 mm. The postoperative UBM image of the sclerotomy site at 8 weeks demonstrated a clear wound without any vitreous adhesion or incarceration. Intraoperative hyphema was seen in 1 (2.8% case and postoperative uveitis was seen in 2 (5.7% cases, which resolved with medications. No case of an iatrogenic retinal break or retinal detachment was reported. Conclusions: PPAV enables a closed chamber approach, allows thorough cleanup of vitreous in the pupillary plane and anterior chamber and affords better access to the subincisional and retropupillary cortical remnant with a significant visual outcome and an acceptable complication rate.

  9. Urokinase-type plasminogen activator receptor (uPAR) as a promising new imaging target

    DEFF Research Database (Denmark)

    Persson, Morten; Kjaer, Andreas

    2013-01-01

    modalities such as optical imaging, magnetic resonance imaging, single photon emission computer tomography (SPECT) and positron emission topography (PET). In this review, we will discuss recent advances in the development of uPAR-targeted imaging ligands according to imaging modality. In addition, we...... will discuss the potential future clinical application for uPAR imaging as a new imaging biomarker....

  10. Pars plana vitrectomy for disturbing primary vitreous floaters: clinical outcome and patient satisfaction

    NARCIS (Netherlands)

    Nie, K.F. de; Crama, N.; Tilanus, M.A.D.; Klevering, B.J.; Boon, C.J.F.

    2013-01-01

    BACKGROUND: Primary vitreous floaters can be highly bothersome in some patients. In the case of persistently bothersome floaters, pars plana vitrectomy may be the most effective treatment. The aim of this study is to evaluate the incidence of complications, and patient satisfaction, after pars plana

  11. Solar PAR and UVR modify the community composition and photosynthetic activity of sea ice algae.

    Science.gov (United States)

    Enberg, Sara; Piiparinen, Jonna; Majaneva, Markus; Vähätalo, Anssi V; Autio, Riitta; Rintala, Janne-Markus

    2015-10-01

    The effects of increased photosynthetically active radiation (PAR) and ultraviolet radiation (UVR) on species diversity, biomass and photosynthetic activity were studied in fast ice algal communities. The experimental set-up consisted of nine 1.44 m(2) squares with three treatments: untreated with natural snow cover (UNT), snow-free (PAR + UVR) and snow-free ice covered with a UV screen (PAR). The total algal biomass, dominated by diatoms and dinoflagellates, increased in all treatments during the experiment. However, the smaller biomass growth in the top 10-cm layer of the PAR + UVR treatment compared with the PAR treatment indicated the negative effect of UVR. Scrippsiella complex (mainly Scrippsiella hangoei, Biecheleria baltica and Gymnodinium corollarium) showed UV sensitivity in the top 5-cm layer, whereas Heterocapsa arctica ssp. frigida and green algae showed sensitivity to both PAR and UVR. The photosynthetic activity was highest in the top 5-cm layer of the PAR treatment, where the biomass of the pennate diatom Nitzschia frigida increased, indicating the UV sensitivity of this species. This study shows that UVR is one of the controlling factors of algal communities in Baltic Sea ice, and that increased availability of PAR together with UVR exclusion can cause changes in algal biomass, photosynthetic activity and community composition. © FEMS 2015. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  12. Spectral variations of UV-A and PAR solar radiation in estuarine waters of Goa

    Digital Repository Service at National Institute of Oceanography (India)

    Talaulikar, M.; Suresh, T.; Silveira, N.; Desa, E.; Matondkar, S; Lotlikar, A

    radiation (400 to 700 nm), PAR and ultraviolet radiation in the range 350-400 nm (UV-A) are presented here. The mean PAR values at the surface were 327 W/m sup(2) and reduced to 84 W/m sup(2) at first optical depth, Z sub(90) (m) in water. The first optical...

  13. Engineering Glass Passivation Layers -Model Results

    Energy Technology Data Exchange (ETDEWEB)

    Skorski, Daniel C.; Ryan, Joseph V.; Strachan, Denis M.; Lepry, William C.

    2011-08-08

    The immobilization of radioactive waste into glass waste forms is a baseline process of nuclear waste management not only in the United States, but worldwide. The rate of radionuclide release from these glasses is a critical measure of the quality of the waste form. Over long-term tests and using extrapolations of ancient analogues, it has been shown that well designed glasses exhibit a dissolution rate that quickly decreases to a slow residual rate for the lifetime of the glass. The mechanistic cause of this decreased corrosion rate is a subject of debate, with one of the major theories suggesting that the decrease is caused by the formation of corrosion products in such a manner as to present a diffusion barrier on the surface of the glass. Although there is much evidence of this type of mechanism, there has been no attempt to engineer the effect to maximize the passivating qualities of the corrosion products. This study represents the first attempt to engineer the creation of passivating phases on the surface of glasses. Our approach utilizes interactions between the dissolving glass and elements from the disposal environment to create impermeable capping layers. By drawing from other corrosion studies in areas where passivation layers have been successfully engineered to protect the bulk material, we present here a report on mineral phases that are likely have a morphological tendency to encrust the surface of the glass. Our modeling has focused on using the AFCI glass system in a carbonate, sulfate, and phosphate rich environment. We evaluate the minerals predicted to form to determine the likelihood of the formation of a protective layer on the surface of the glass. We have also modeled individual ions in solutions vs. pH and the addition of aluminum and silicon. These results allow us to understand the pH and ion concentration dependence of mineral formation. We have determined that iron minerals are likely to form a complete incrustation layer and we plan

  14. Will Passive Protection Save Congo Forests?

    Science.gov (United States)

    Galford, Gillian L.; Soares-Filho, Britaldo S.; Sonter, Laura J.; Laporte, Nadine

    2015-01-01

    Central Africa’s tropical forests are among the world’s largest carbon reserves. Historically, they have experienced low rates of deforestation. Pressures to clear land are increasing due to development of infrastructure and livelihoods, foreign investment in agriculture, and shifting land use management, particularly in the Democratic Republic of Congo (DRC). The DRC contains the greatest area of intact African forests. These store approximately 22 billion tons of carbon in aboveground live biomass, yet only 10% are protected. Can the status quo of passive protection — forest management that is low or nonexistent — ensure the preservation of this forest and its carbon? We have developed the SimCongo model to simulate changes in land cover and land use based on theorized policy scenarios from 2010 to 2050. Three scenarios were examined: the first (Historical Trends) assumes passive forest protection; the next (Conservation) posits active protection of forests and activation of the national REDD+ action plan, and the last (Agricultural Development) assumes increased agricultural activities in forested land with concomitant increased deforestation. SimCongo is a cellular automata model based on Bayesian statistical methods tailored for the DRC, built with the Dinamica-EGO platform. The model is parameterized and validated with deforestation observations from the past and runs the scenarios from 2010 through 2050 with a yearly time step. We estimate the Historical Trends trajectory will result in average emissions of 139 million t CO2 year-1 by the 2040s, a 15% increase over current emissions. The Conservation scenario would result in 58% less clearing than Historical Trends and would conserve carbon-dense forest and woodland savanna areas. The Agricultural Development scenario leads to emissions of 212 million t CO2 year-1 by the 2040s. These scenarios are heuristic examples of policy’s influence on forest conservation and carbon storage. Our results

  15. Narrative Identities and the Plebiscite in Pará: An Analysis of the Front Pages for O Liberal and Diário do Pará

    Directory of Open Access Journals (Sweden)

    Alda Cristina Silva da Costa

    2017-05-01

    Full Text Available On December 11, 2011, a plebiscite was held in Pará proposing to create two separatist states, Carajás and Tapajós, out of the state of Pará. The public voted against both projects. This article analyzes the narrative identities found on the front pages of O Liberal and Diário do Pará newspapers about the plebiscite in Pará. Depth Hermeneutics (DH, as proposed by Thompson (2011, was used as the methodological reference. DH emphasizes the object of analysis as a meaningful symbolic construction requiring interpretation. Narrative analysis, as proposed by Motta (2007, was the main research technique used to highlight the movement of construction of journalistic (discursive characters. The narrative identities built by the two newspapers showed that both were against the creation of the new states, but for very different reasons. The flag of Pará was the main object used to induce the idea of unity. Em 11 de dezembro de 2011, o plebiscito no Pará propôs a criação dos estados de Carajás e de Tapajós a partir da divisão do estado do Pará. O resultado da consulta pública foi negativo aos dois projetos. O artigo analisa as identidades narrativas constituídas pelas primeiras páginas dos jornais O Liberal e Diário do Pará sobre o plebiscito no Pará. Utilizou-se como referencial metodológico a Hermenêutica em Profundidade (HP, proposta por Thompson (2011. A HP evidencia o fato de que o objeto de análise é uma construção simbólica significativa, que exige uma interpretação. Como principal técnica de pesquisa, a análise narrativa, proposta por Motta (2007, com ênfase no movimento de construção de personagens jornalísticas (discursivas. As identidades narrativas construídas pelos dois jornais indicaram que ambos eram contrários à criação dos novos estados, porém por motivos divergentes. A bandeira do Pará foi o principal elemento utilizado para evocar a ideia de unidade. En 11 de diciembre de 2011, el plebiscito en

  16. The urokinase receptor (uPAR) and the uPAR-associated protein (uPARAP/Endo180)

    DEFF Research Database (Denmark)

    Behrendt, Niels

    2004-01-01

    The breakdown of the barriers formed by extracellular matrix proteins is a pre-requisite for all processes of tissue remodeling. Matrix degradation reactions take part in specific physiological events in the healthy organism but also represent a crucial step in cancer invasion. These degradation...... on the surface of various cell types that serves to bind the urokinase plasminogen activator and localize the activation reactions in the proteolytic cascade system of plasminogen activation. uPARAP is an integral membrane protein with a pronounced role in the internalization of collagen for intracellular...... degradation. Both receptors have additional functions that are currently being unraveled. The present discussion of uPAR and uPARAP is centered on their protein structure and molecular and cellular function....

  17. Effect of simvastatin and ezetimibe on suPAR levels and outcomes

    DEFF Research Database (Denmark)

    Hodges, Gethin W; Bang, Casper N; Forman, Julie L

    2018-01-01

    -lowering therapy also lowers suPAR levels is unknown. METHODS: We investigated whether treatment with Simvastatin 40 mg and Ezetimibe 10 mg lowered plasma suPAR levels in 1838 patients with mild-moderate, asymptomatic aortic stenosis, included in the Simvastatin and Ezetimibe in Aortic Stenosis (SEAS) study, using...... and Ezetimibe treatment impeded the progression of the time-related increase in plasma suPAR levels. Year-1 suPAR was associated with all-cause mortality, MCE, and AVE irrespective of baseline levels (SEAS study: NCT00092677)....... cardiovascular events (MCE) composed of ischemic cardiovascular events (ICE) and aortic valve related events (AVE). RESULTS: After 4.3 years of follow-up, suPAR levels had increased by 9.2% (95% confidence interval [CI]: 7.0%-11.5%) in the placebo group, but only by 4.1% (1.9%-6.2%) in the group with lipid...

  18. Brulure par Plaque de Bistouri Electrique: a Propos de Quatre Cas

    Science.gov (United States)

    Khales, A.; Achbouk, A.; Belmir, R.; Cherkab, L.; Ennouhi, M.A.; Ababou, K.; Ihrai, H.

    2010-01-01

    Summary La brûlure par plaque de bistouri électrique est un accident rare mais grave par la profondeur de la lésion et par sa localisation, surtout quand qu’elle survient dans un contexte chirurgical dont le vécu reste difficile de la part du malade et du chirurgien. Cette brûlure bien que imprévisible reste grave par la profondeur et la localisation de la brûlure et par sa survenue dans un contexte opératoire, chez des patients malades. La prise en charge de la brûlure doit se faire en milieu spécialisé. La prévention reste le seul moyen d’éviter ce type d’accident. PMID:21991216

  19. Potential dependence of surface crystal structure of iron passive films in borate buffer solution

    International Nuclear Information System (INIS)

    Deng, Huihua; Nanjo, Hiroshi; Qian, Pu; Santosa, Arifin; Ishikawa, Ikuo; Kurata, Yoshiaki

    2007-01-01

    The effect of passivation potential on surface crystal structure, apparent thickness and passivity of oxide films formed on pure iron prepared by plasma sputter deposition was investigated. The crystallinity was improved with passivation potential and the width of atomically flat terraces was expanded to 6 nm when passivating at 750 mV for 15 min, as observed by ex situ scanning tunneling microscopy (STM) after aging in air (<30% RH). Apparent thickness and passivity are linearly dependent on passivation potential. The former weakly depends on passivation duration, the latter strongly depends on passivation duration. This is well explained by the correlation between crystal structure and passivity

  20. par genes in Mycobacterium bovis and Mycobacterium smegmatis are arranged in an operon transcribed from "SigGC" promoters

    Directory of Open Access Journals (Sweden)

    Casart Yveth

    2008-03-01

    Full Text Available Abstract Background The ParA/Soj and ParB/Spo0J proteins, and the cis-acting parS site, participate actively in chromosome segregation and cell cycle progression. Genes homologous to parA and parB, and two putative parS copies, have been identified in the Mycobacterium bovis BCG and Mycobacterium smegmatis chromosomes. As in Mycobacterium tuberculosis, the parA and parB genes in these two non-pathogenic mycobacteria are located near the chromosomal origin of replication. The present work focused on the determination of the transcriptional organisation of the ~6 Kb orf60K-parB region of M. bovis BCG and M. smegmatis by primer extension, transcriptional fusions to the green fluorescence protein (GFP and quantitative RT-PCR. Results The parAB genes were arranged in an operon. However, we also found promoters upstream of each one of these genes. Seven putative promoter sequences were identified in the orf60K-parB region of M. bovis BCG, whilst four were identified in the homologous region of M. smegmatis, one upstream of each open reading frame (ORF. Real-time PCR assays showed that in M. smegmatis, mRNA-parA and mRNA-parB levels decreased between the exponential and stationary phases. In M. bovis BCG, mRNA-parA levels also decreased between the exponential and stationary phases. However, parB expression was higher than parA expression and remained almost unchanged along the growth curve. Conclusion The majority of the proposed promoter regions had features characteristic of Mycobacterium promoters previously denoted as Group D. The -10 hexamer of a strong E. coli σ70-like promoter, located upstream of gidB of M. bovis BCG, overlapped with a putative parS sequence, suggesting that the transcription from this promoter might be regulated by the binding of ParB to parS.