PANDAS: uma nova doença? PANDAS: a new disease?

Directory of Open Access Journals (Sweden)

Sheila Knupp Feitosa de Oliveira

2007-06-01

Full Text Available OBJETIVO: Apresentar as bases diagnósticas e analisar as evidências que têm sido apontadas para a etiopatogenia, tratamento e profilaxia de PANDAS. FONTES DOS DADOS: Revisão de literatura científica através do MEDLINE no período de 1989 a 2006. SÍNTESE DOS DADOS: Os critérios diagnósticos para PANDAS foram estabelecidos há quase 10 anos, mas ainda há muita controvérsia sobre a real existência desta nova doença pediátrica. A escolha deste nome para uma nova doença, supostamente de origem pós-estreptocócica, baseia-se no acrônimo de P (pediátrico, porque ocorre em crianças, A (auto-imune, N (neuropsiquiátrico, D (doença, A (associada e S (Streptococcus. Os tiques e os sintomas obsessivo-compulsivos são as principais manifestações clínicas da doença e surgem após infecções estreptocócicas, provavelmente por mecanismos auto-imunes. Apesar de estes sintomas neuropsiquiátricos serem comuns na coréia reumática, também de etiologia pós-estreptocócica, em PANDAS faltam os movimentos clássicos da coréia e as outras manifestações de febre reumática. As possibilidades de terapia antimicrobiana e imunológica estão sendo pesquisadas e demonstram viabilidade de uso em alguns casos. CONCLUSÕES: Pesquisas ainda são necessárias para responder à pergunta-título. Enquanto isso não ocorre, a identificação de casos de tiques e transtorno obsessivo-compulsivo em crianças deve considerar a possibilidade de PANDAS, buscando a evidência de infecção estreptocócica precedendo os episódios.OBJECTIVE: To establish the diagnostic criteria for PANDAS and to analyze the existing evidence regarding its etiopathogenesis, treatment and prophylaxis. SOURCES: Review of the scientific literature through a MEDLINE search carried out between 1989 and 2006. SUMMARY OF THE FINDINGS: The diagnostic criteria for PANDAS were established nearly 10 years ago, but a lot of controversy still exists over the actual existence of this new

Should the Endangered Status of the Giant Panda Really Be Reduced? The Case of Giant Panda Conservation in Sichuan, China.

Science.gov (United States)

Ma, Ben; Lei, Shuo; Qing, Qin; Wen, Yali

2018-05-03

The International Union for Conservation of Nature (IUCN) reduced the threat status of the giant panda from “endangered” to “vulnerable” in September 2016. In this study, we analyzed current practices for giant panda conservation at regional and local environmental scales, based on recent reports of giant panda protection efforts in Sichuan Province, China, combined with the survey results from 927 households within and adjacent to the giant panda reserves in this area. The results showed that household attitudes were very positive regarding giant panda protection efforts. Over the last 10 years, farmers’ dependence on the natural resources provided by giant panda reserves significantly decreased. However, socio-economic development increased resource consumption, and led to climate change, habitat fragmentation, environmental pollution, and other issues that placed increased pressure on giant panda populations. This difference between local and regional scales must be considered when evaluating the IUCN status of giant pandas. While the status of this species has improved in the short-term due to positive local attitudes, large-scale socio-economic development pressure could have long-term negative impacts. Consequently, the IUCN assessment leading to the classification of giant panda as “vulnerable” instead of “endangered”, should not affect its conservation intensity and effort, as such actions could negatively impact population recovery efforts, leading to the extinction of this charismatic species.

Should the Endangered Status of the Giant Panda Really Be Reduced? The Case of Giant Panda Conservation in Sichuan, China

Directory of Open Access Journals (Sweden)

Ben Ma

2018-05-01

Full Text Available The International Union for Conservation of Nature (IUCN reduced the threat status of the giant panda from “endangered” to “vulnerable” in September 2016. In this study, we analyzed current practices for giant panda conservation at regional and local environmental scales, based on recent reports of giant panda protection efforts in Sichuan Province, China, combined with the survey results from 927 households within and adjacent to the giant panda reserves in this area. The results showed that household attitudes were very positive regarding giant panda protection efforts. Over the last 10 years, farmers’ dependence on the natural resources provided by giant panda reserves significantly decreased. However, socio-economic development increased resource consumption, and led to climate change, habitat fragmentation, environmental pollution, and other issues that placed increased pressure on giant panda populations. This difference between local and regional scales must be considered when evaluating the IUCN status of giant pandas. While the status of this species has improved in the short-term due to positive local attitudes, large-scale socio-economic development pressure could have long-term negative impacts. Consequently, the IUCN assessment leading to the classification of giant panda as “vulnerable” instead of “endangered”, should not affect its conservation intensity and effort, as such actions could negatively impact population recovery efforts, leading to the extinction of this charismatic species.

Open-charm physics opportunities at PANDA

Energy Technology Data Exchange (ETDEWEB)

Prencipe, Elisabetta; Cao, Lu; Herten, Andreas; Ritman, James [IKP, Forschungszentrum Juelich (Germany); Kang, Donghee [Johannes Gutenberg Universitaet Mainz (Germany); Pitka, Andreas [Justus-Liebig Universitaet Giessen (Germany); Collaboration: PANDA-Collaboration

2015-07-01

Open-charm physics is of high interest for the weak and the strong interactions. New observations in spectroscopy and the recent constraining limits on CP violation in the D sector strongly motivate the study of open-charm physics. The experiment PANDA at FAIR (Darmstadt) will investigate fundamental questions of hadron and nuclear physics in interactions of antiprotons with nucleons and nuclei. Among other topics, original contributions are planned from PANDA in the open-charm sector. With high average reaction rates up to 2.10{sup 7} interactions/s, and a factor 20 higher mass resolution than attained at B-factories, PANDA is in a privileged position to perform measurements of widths of narrow states, such as the D{sub s}(2317){sup +} and the D{sub s}(2460){sup +}, and form factors in semileptonic D{sub s} decays. Very rare processes (e.g. D{sup 0} → γγ) can be accessible with unprecedented accuracy. In addition, the search for new physics is a challenge that PANDA can take, for example with the study of the mixing in the D sector, analyzing the channel anti pp → ψ(3770) → anti D{sup 0}D{sup 0}. PANDA is expected to be decisive to answer on these and second-order open questions. A general overview of the benchmark channels in the D sector with PANDA is given in this report, showing the results of recent PandaRoot simulations.

Three cases giant panda attack on human at Beijing Zoo.

Science.gov (United States)

Zhang, Peixun; Wang, Tianbing; Xiong, Jian; Xue, Feng; Xu, Hailin; Chen, Jianhai; Zhang, Dianying; Fu, Zhongguo; Jiang, Baoguo

2014-01-01

Panda is regarded as Chinese national treasure. Most people always thought they were cute and just ate bamboo and had never imagined a panda could be vicious. Giant panda attacks on human are rare. There, we present three cases of giant panda attacks on humans at the Panda House at Beijing Zoo from September 2006 to June 2009 to warn people of the giant panda's potentially dangerous behavior.

PandA : pairings and arithmetic

NARCIS (Netherlands)

Chuengsatiansup, C.; Naehrig, M.; Ribarski, P.; Schwabe, P.; Cao, Z.; Zhang, F.

2014-01-01

This paper introduces PandA, a software framework for Pairings and Arithmetic. It is designed to bring together advances in the efficient computation of cryptographic pairings and the development and implementation of pairing-based protocols. The intention behind the PandA framework is to give

Modeling Impacts of Climate Change on Giant Panda Habitat

Directory of Open Access Journals (Sweden)

Melissa Songer

2012-01-01

Full Text Available Giant pandas (Ailuropoda melanoleuca are one of the most widely recognized endangered species globally. Habitat loss and fragmentation are the main threats, and climate change could significantly impact giant panda survival. We integrated giant panda habitat information with general climate models (GCMs to predict future geographic distribution and fragmentation of giant panda habitat. Results support a major general prediction of climate change—a shift of habitats towards higher elevation and higher latitudes. Our models predict climate change could reduce giant panda habitat by nearly 60% over 70 years. New areas may become suitable outside the current geographic range but much of these areas is far from the current giant panda range and only 15% fall within the current protected area system. Long-term survival of giant pandas will require the creation of new protected areas that are likely to support suitable habitat even if the climate changes.

Gestión del talento humano y competencias laborales del personal del hospital Hermilio Valdizán 2016

OpenAIRE

Serpa Reyes, Elisa Soledad

2016-01-01

La presente investigación tuvo como objetivo general, Conocer la relación que existe entre gestión del talento humano y las competencias laborales del personal del hospital Hermilio Valdizán en el año 2016. El tipo de investigación es no experimental, de diseño descriptivo correlacional. La población fue de 709 trabajadores, y la muestra de 217 trabajadores del hospital Hermilio Valdizán, la muestra es probabilística aleatoria simple. Se aplicó el cuestionario de gestión del...

Role of nature reserves in giant panda protection.

Science.gov (United States)

Kang, Dongwei; Li, Junqing

2018-02-01

Giant panda (Ailuropoda melanoleuca) is a flagship species in nature conservation of the world; to protect this species, 67 nature reserves have been established in China. To evaluate the protection effect of giant panda nature reserves, we analyzed the variation of giant panda number and habitat area of 23 giant panda nature reserves of Sichuan province based on the national survey data released by State Forestry Administration and Sichuan Forestry Department. Results showed that from the third national survey to the fourth, giant panda number and habitat area of 23 giant panda nature reserves of Sichuan province failed to realize the significant increase. Furthermore, we found that the total population growth rate of 23 nature reserves in the last 12 years was lower than those of the province total of Sichuan and the national total of China, and the total habitat area of the 23 nature reserves was decreasing in the last 12 years, but the province total and national total were all increasing. We propose that giant panda protection should pay more attention to how to improve the protective effects of nature reserves.

The PANDA Barrel DIRC

Science.gov (United States)

Schwiening, J.; Ali, A.; Belias, A.; Dzhygadlo, R.; Gerhardt, A.; Götzen, K.; Kalicy, G.; Krebs, M.; Lehmann, D.; Nerling, F.; Patsyuk, M.; Peters, K.; Schepers, G.; Schmitt, L.; Schwarz, C.; Traxler, M.; Böhm, M.; Eyrich, W.; Lehmann, A.; Pfaffinger, M.; Uhlig, F.; Düren, M.; Etzelmüller, E.; Föhl, K.; Hayrapetyan, A.; Kreutzfeld, K.; Merle, O.; Rieke, J.; Schmidt, M.; Wasem, T.; Achenbach, P.; Cardinali, M.; Hoek, M.; Lauth, W.; Schlimme, S.; Sfienti, C.; Thiel, M.

2018-03-01

The PANDA experiment at the international accelerator Facility for Antiproton and Ion Research in Europe (FAIR) near GSI, Darmstadt, Germany will address fundamental questions of hadron physics. Excellent Particle Identification (PID) over a large range of solid angles and particle momenta will be essential to meet the objectives of the rich physics program. Charged PID for the barrel region of the PANDA target spectrometer will be provided by a DIRC (Detection of Internally Reflected Cherenkov light) detector. The Barrel DIRC will cover the polar angle range of 22o-140o and cleanly separate charged pions from kaons for momenta between 0.5 GeV/c and 3.5 GeV/c with a separation power of at least 3 standard deviations. The design is based on the successful BABAR DIRC and the SuperB FDIRC R&D with several important improvements to optimize the performance for PANDA, such as a focusing lens system, fast timing, a compact fused silica prism as expansion region, and lifetime-enhanced Microchannel-Plate PMTs for photon detection. This article describes the technical design of the PANDA Barrel DIRC and the result of the design validation using a "vertical slice" prototype in hadronic particle beams at the CERN PS.

Three cases giant panda attack on human at Beijing Zoo

OpenAIRE

Zhang, Peixun; Wang, Tianbing; Xiong, Jian; Xue, Feng; Xu, Hailin; Chen, Jianhai; Zhang, Dianying; Fu, Zhongguo; Jiang, Baoguo

2014-01-01

Panda is regarded as Chinese national treasure. Most people always thought they were cute and just ate bamboo and had never imagined a panda could be vicious. Giant panda attacks on human are rare. There, we present three cases of giant panda attacks on humans at the Panda House at Beijing Zoo from September 2006 to June 2009 to warn people of the giant panda’s potentially dangerous behavior.

Overview of ATLAS PanDA Workload Management

Science.gov (United States)

Maeno, T.; De, K.; Wenaus, T.; Nilsson, P.; Stewart, G. A.; Walker, R.; Stradling, A.; Caballero, J.; Potekhin, M.; Smith, D.; ATLAS Collaboration

2011-12-01

The Production and Distributed Analysis System (PanDA) plays a key role in the ATLAS distributed computing infrastructure. All ATLAS Monte-Carlo simulation and data reprocessing jobs pass through the PanDA system. We will describe how PanDA manages job execution on the grid using dynamic resource estimation and data replication together with intelligent brokerage in order to meet the scaling and automation requirements of ATLAS distributed computing. PanDA is also the primary ATLAS system for processing user and group analysis jobs, bringing further requirements for quick, flexible adaptation to the rapidly evolving analysis use cases of the early datataking phase, in addition to the high reliability, robustness and usability needed to provide efficient and transparent utilization of the grid for analysis users. We will describe how PanDA meets ATLAS requirements, the evolution of the system in light of operational experience, how the system has performed during the first LHC data-taking phase and plans for the future.

Overview of ATLAS PanDA Workload Management

International Nuclear Information System (INIS)

Maeno, T.; De, K.; Wenaus, T.; Nilsson, P.; Stewart, G.A.; Walker, R.; Stradling, A.; Caballero, J.; Potekhin, M.; Smith, D.

2011-01-01

The Production and Distributed Analysis System (PanDA) plays a key role in the ATLAS distributed computing infrastructure. All ATLAS Monte-Carlo simulation and data reprocessing jobs pass through the PanDA system. We will describe how PanDA manages job execution on the grid using dynamic resource estimation and data replication together with intelligent brokerage in order to meet the scaling and automation requirements of ATLAS distributed computing. PanDA is also the primary ATLAS system for processing user and group analysis jobs, bringing further requirements for quick, flexible adaptation to the rapidly evolving analysis use cases of the early datataking phase, in addition to the high reliability, robustness and usability needed to provide efficient and transparent utilization of the grid for analysis users. We will describe how PanDA meets ATLAS requirements, the evolution of the system in light of operational experience, how the system has performed during the first LHC data-taking phase and plans for the future.

A PanDA backend for the ganga analysis interface

International Nuclear Information System (INIS)

Vanderster, D C; Elmsheuser, J; Walker, R; Liko, D; Maeno, T; Wenaus, T; Nilsson, P

2010-01-01

Ganga provides a uniform interface for running ATLAS user analyses on a number of local, batch, and grid backends. PanDA is a pilot-based production and distributed analysis system developed and used extensively by ATLAS. This work presents the implementation and usage experiences of a PanDA backend for Ganga. Built upon reusable application libraries from GangaAtlas and PanDA, the Ganga PanDA backend allows users to run their analyses on the worldwide PanDA resources, while providing the ability for users to develop simple or complex analysis workflows in Ganga. Further, the backend allows users to submit and manage 'personal' PanDA pilots: these pilots run under the user's grid certificate and provide a secure alternative to shared pilot certificates while enabling the usage of local resource allocations.

Fatal canine distemper virus infection of giant pandas in China.

Science.gov (United States)

Feng, Na; Yu, Yicong; Wang, Tiecheng; Wilker, Peter; Wang, Jianzhong; Li, Yuanguo; Sun, Zhe; Gao, Yuwei; Xia, Xianzhu

2016-06-16

We report an outbreak of canine distemper virus (CDV) infection among endangered giant pandas (Ailuropoda melanoleuca). Five of six CDV infected giant pandas died. The surviving giant panda was previously vaccinated against CDV. Genomic sequencing of CDV isolated from one of the infected pandas (giant panda/SX/2014) suggests it belongs to the Asia-1 cluster. The hemagglutinin protein of the isolated virus and virus sequenced from lung samples originating from deceased giant pandas all possessed the substitutions V26M, T213A, K281R, S300N, P340Q, and Y549H. The presence of the Y549H substitution is notable as it is found at the signaling lymphocytic activation molecule (SLAM) receptor-binding site and has been implicated in the emergence of highly pathogenic CDV and host switching. These findings demonstrate that giant pandas are susceptible to CDV and suggest that surveillance and vaccination among all captive giant pandas are warranted to support conservation efforts for this endangered species.

Characterization of the gut microbiota in the red panda (Ailurus fulgens).

Science.gov (United States)

Kong, Fanli; Zhao, Jiangchao; Han, Shushu; Zeng, Bo; Yang, Jiandong; Si, Xiaohui; Yang, Benqing; Yang, Mingyao; Xu, Huailiang; Li, Ying

2014-01-01

The red panda is the only living species of the genus Ailurus. Like giant pandas, red pandas are also highly specialized to feed mainly on highly fibrous bamboo. Although several studies have focused on the gut microbiota in the giant panda, little is known about the gut microbiota of the red panda. In this study, we characterized the fecal microbiota from both wild (n = 16) and captive (n = 6) red pandas using a pyrosequecing based approach targeting the V1-V3 hypervariable regions of the 16S rRNA gene. Distinct bacterial communities were observed between the two groups based on both membership and structure. Wild red pandas maintained significantly higher community diversity, richness and evenness than captive red pandas, the communities of which were skewed and dominated by taxa associated with Firmicutes. Phylogenetic analysis of the top 50 OTUs revealed that 10 of them were related to known cellulose degraders. To the best of our knowledge, this is the first study of the gut microbiota of the red panda. Our data suggest that, similar to the giant panda, the gut microbiota in the red panda might also play important roles in the digestion of bamboo.

A PandaRoot interface for binary data in the PANDA prototype DAQ system

Energy Technology Data Exchange (ETDEWEB)

Fleischer, Soeren; Lange, Soeren; Kuehn, Wolfgang; Hahn, Christopher; Wagner, Milan [2. Physikalisches Institut, Uni Giessen (Germany); Collaboration: PANDA-Collaboration

2015-07-01

The PANDA experiment at FAIR will feature a raw data rate of more than 20 MHz. Only a small fraction of these events are of interest. Consequently, a sophisticated online data reduction setup is required, lowering the final output data rate by a factor of roughly 10{sup 3} by discarding data which does not fulfil certain criteria. The first stages of the data reduction will be implemented using FPGA-based Compute Nodes. For the planned tests with prototype detectors a small but scalable system is being set up which will allow to test the concept in a realistic environment with high rates. In this contribution, we present a PandaRoot implementation of a state-machine-based binary parser which receives detector data from the Compute Nodes via GbE links, converting the data stream into the PandaRoot format for further analysis and mass storage.

Characterization of the gut microbiota in the red panda (Ailurus fulgens.

Directory of Open Access Journals (Sweden)

Fanli Kong

Full Text Available The red panda is the only living species of the genus Ailurus. Like giant pandas, red pandas are also highly specialized to feed mainly on highly fibrous bamboo. Although several studies have focused on the gut microbiota in the giant panda, little is known about the gut microbiota of the red panda. In this study, we characterized the fecal microbiota from both wild (n = 16 and captive (n = 6 red pandas using a pyrosequecing based approach targeting the V1-V3 hypervariable regions of the 16S rRNA gene. Distinct bacterial communities were observed between the two groups based on both membership and structure. Wild red pandas maintained significantly higher community diversity, richness and evenness than captive red pandas, the communities of which were skewed and dominated by taxa associated with Firmicutes. Phylogenetic analysis of the top 50 OTUs revealed that 10 of them were related to known cellulose degraders. To the best of our knowledge, this is the first study of the gut microbiota of the red panda. Our data suggest that, similar to the giant panda, the gut microbiota in the red panda might also play important roles in the digestion of bamboo.

PANDA: Protein function prediction using domain architecture and affinity propagation.

Science.gov (United States)

Wang, Zheng; Zhao, Chenguang; Wang, Yiheng; Sun, Zheng; Wang, Nan

2018-02-22

We developed PANDA (Propagation of Affinity and Domain Architecture) to predict protein functions in the format of Gene Ontology (GO) terms. PANDA at first executes profile-profile alignment algorithm to search against PfamA, KOG, COG, and SwissProt databases, and then launches PSI-BLAST against UniProt for homologue search. PANDA integrates a domain architecture inference algorithm based on the Bayesian statistics that calculates the probability of having a GO term. All the candidate GO terms are pooled and filtered based on Z-score. After that, the remaining GO terms are clustered using an affinity propagation algorithm based on the GO directed acyclic graph, followed by a second round of filtering on the clusters of GO terms. We benchmarked the performance of all the baseline predictors PANDA integrates and also for every pooling and filtering step of PANDA. It can be found that PANDA achieves better performances in terms of area under the curve for precision and recall compared to the baseline predictors. PANDA can be accessed from http://dna.cs.miami.edu/PANDA/ .

Fatal canine distemper virus infection of giant pandas in China

Science.gov (United States)

Feng, Na; Yu, Yicong; Wang, Tiecheng; Wilker, Peter; Wang, Jianzhong; Li, Yuanguo; Sun, Zhe; Gao, Yuwei; Xia, Xianzhu

2016-01-01

We report an outbreak of canine distemper virus (CDV) infection among endangered giant pandas (Ailuropoda melanoleuca). Five of six CDV infected giant pandas died. The surviving giant panda was previously vaccinated against CDV. Genomic sequencing of CDV isolated from one of the infected pandas (giant panda/SX/2014) suggests it belongs to the Asia-1 cluster. The hemagglutinin protein of the isolated virus and virus sequenced from lung samples originating from deceased giant pandas all possessed the substitutions V26M, T213A, K281R, S300N, P340Q, and Y549H. The presence of the Y549H substitution is notable as it is found at the signaling lymphocytic activation molecule (SLAM) receptor-binding site and has been implicated in the emergence of highly pathogenic CDV and host switching. These findings demonstrate that giant pandas are susceptible to CDV and suggest that surveillance and vaccination among all captive giant pandas are warranted to support conservation efforts for this endangered species. PMID:27310722

Tracing the origin of the panda's thumb

Science.gov (United States)

Abella, Juan; Pérez-Ramos, Alejandro; Valenciano, Alberto; Alba, David M.; Ercoli, Marcos D.; Hontecillas, Daniel; Montoya, Plinio; Morales, Jorge

2015-06-01

We investigate the relative development of the carnivoran radial sesamoids to untangle the evolution of this iconic structure. In the pandas (both giant and red), this `false thumb' is known to perform a grasping role during bamboo feeding in both the red and giant pandas. An original locomotor role has been inferred for ailurids, but this remains to be ascertained for ursids. A large sample of radial sesamoids of Indarctos arctoides from the Miocene of Batallones-3 (Spain) indicates that this early ailuropodine bear displayed a relatively hypertrophied radial sesamoid, with a configuration more similar to that of the red panda and other carnivorans than to that of giant pandas. This false thumb is the first evidence of this feature in the Ursidae, which can be linked to a more herbivorous diet. Moreover, in the two extant pandas, the false thumb should not be interpreted as an anatomical convergence, but as an exaptive convergence regarding its use during the bamboo feeding, which changes the evolutionary view of this singular structure.

Current husbandry situation of red pandas in Japan.

Science.gov (United States)

Tanaka, Ai; Ogura, Tadatoshi

2018-03-01

The red panda (Ailurus fulgens) is an endangered semi-arboreal folivore with a specialized diet of bamboo leaves. Zoos worldwide maintain red pandas under a variety of housing environments and husbandry procedures that may affect the reproductive success and longevity of captive red pandas. The aims of the present study were to investigate how red pandas are kept in Japan and to obtain useful insights to increase their longevity by comparing the results from a questionnaire sent to Japanese zoos and those from a previous survey conducted in other countries. We received responses from 42 out of 52 zoos, holding a total of 219 individual red pandas, in Japan. The age-sex distribution indicated that red panda populations in Japan need close attention to be maintained sustainably. Of the husbandry aspects surveyed, the number of individuals in the same zoo, enclosure size, and the frequency of bamboo feeding factors indicated to affect reproductive success. Frequent monitoring of body weight, implementation of husbandry training, and bamboo feeding were also suggested as the reasons for the longevity of red pandas in Japan. Zoos were provided with sufficient physical features in on-exhibit enclosures, close monitoring for health status, and proper feeding, but other aspects of husbandry such as enclosure size and structures in off-exhibit spaces were insufficient and might compromise animal welfare. © 2018 Wiley Periodicals, Inc.

Observing giant panda habitat and forage abundance from space

NARCIS (Netherlands)

Wang, T.

2009-01-01

Giant pandas are obligate bamboo grazers. The bamboos favoured by giant
pandas are typical forest understorey plants. Therefore, the availability and
abundance of understorey bamboo is a key factor in determining the quantity
and quality of giant panda food resources. However,

Metabolic rates of giant pandas inform conservation strategies

Science.gov (United States)

Fei, Yuxiang; Hou, Rong; Spotila, James R.; Paladino, Frank V.; Qi, Dunwu; Zhang, Zhihe

2016-06-01

The giant panda is an icon of conservation and survived a large-scale bamboo die off in the 1980s in China. Captive breeding programs have produced a large population in zoos and efforts continue to reintroduce those animals into the wild. However, we lack sufficient knowledge of their physiological ecology to determine requirements for survival now and in the face of climate change. We measured resting and active metabolic rates of giant pandas in order to determine if current bamboo resources were sufficient for adding additional animals to populations in natural reserves. Resting metabolic rates were somewhat below average for a panda sized mammal and active metabolic rates were in the normal range. Pandas do not have exceptionally low metabolic rates. Nevertheless, there is enough bamboo in natural reserves to support both natural populations and large numbers of reintroduced pandas. Bamboo will not be the limiting factor in successful reintroduction.

The ̅PANDA Detector at FAIR

International Nuclear Information System (INIS)

Ikegami Andersson, W

2016-01-01

The future ̅PANDA detector at FAIR is a state-of-the-art internal target detector designed for strong interaction studies. By utilizing an antiproton beam, a rich and unique physics programme is planned. The ̅PANDA experiment, as well as feasibility studies for hyperon and charmonium physics, are discussed. (paper)

The ̅PANDA Detector at FAIR

Science.gov (United States)

Ikegami Andersson, W.; ̅PANDA Collaboration

2016-11-01

The future ̅PANDA detector at FAIR is a state-of-the-art internal target detector designed for strong interaction studies. By utilizing an antiproton beam, a rich and unique physics programme is planned. The ̅PANDA experiment, as well as feasibility studies for hyperon and charmonium physics, are discussed.

Migration of ATLAS PanDA to CERN

International Nuclear Information System (INIS)

Stewart, Graeme Andrew; Klimentov, Alexei; Maeno, Tadashi; Nevski, Pavel; Nowak, Marcin; De Castro Faria Salgado, Pedro Emanuel; Wenaus, Torre; Koblitz, Birger; Lamanna, Massimo

2010-01-01

The ATLAS Production and Distributed Analysis System (PanDA) is a key component of the ATLAS distributed computing infrastructure. All ATLAS production jobs, and a substantial amount of user and group analysis jobs, pass through the PanDA system, which manages their execution on the grid. PanDA also plays a key role in production task definition and the data set replication request system. PanDA has recently been migrated from Brookhaven National Laboratory (BNL) to the European Organization for Nuclear Research (CERN), a process we describe here. We discuss how the new infrastructure for PanDA, which relies heavily on services provided by CERN IT, was introduced in order to make the service as reliable as possible and to allow it to be scaled to ATLAS's increasing need for distributed computing. The migration involved changing the backend database for PanDA from MySQL to Oracle, which impacted upon the database schemas. The process by which the client code was optimised for the new database backend is discussed. We describe the procedure by which the new database infrastructure was tested and commissioned for production use. Operations during the migration had to be planned carefully to minimise disruption to ongoing ATLAS offline computing. All parts of the migration were fully tested before commissioning the new infrastructure and the gradual migration of computing resources to the new system allowed any problems of scaling to be addressed.

Event Reconstruction in the PandaRoot framework

International Nuclear Information System (INIS)

Spataro, Stefano

2012-01-01

The PANDA experiment will study the collisions of beams of anti-protons, with momenta ranging from 2-15 GeV/c, with fixed proton and nuclear targets in the charm energy range, and will be built at the FAIR facility. In preparation for the experiment, the PandaRoot software framework is under development for detector simulation, reconstruction and data analysis, running on an Alien2-based grid. The basic features are handled by the FairRoot framework, based on ROOT and Virtual Monte Carlo, while the PANDA detector specifics and reconstruction code are implemented inside PandaRoot. The realization of Technical Design Reports for the tracking detectors has pushed the finalization of the tracking reconstruction code, which is complete for the Target Spectrometer, and of the analysis tools. Particle Identification algorithms are currently implemented using Bayesian approach and compared to Multivariate Analysis methods. Moreover, the PANDA data acquisition foresees a triggerless operation in which events are not defined by a hardware 1st level trigger decision, but all the signals are stored with time stamps requiring a deconvolution by the software. This has led to a redesign of the software from an event basis to a time-ordered structure. In this contribution, the reconstruction capabilities of the Panda spectrometer will be reported, focusing on the performances of the tracking system and the results for the analysis of physics benchmark channels, as well as the new (and challenging) concept of time-based simulation and its implementation.

Metabolic rates of giant pandas inform conservation strategies

Science.gov (United States)

Fei, Yuxiang; Hou, Rong; Spotila, James R.; Paladino, Frank V.; Qi, Dunwu; Zhang, Zhihe

2016-01-01

The giant panda is an icon of conservation and survived a large-scale bamboo die off in the 1980s in China. Captive breeding programs have produced a large population in zoos and efforts continue to reintroduce those animals into the wild. However, we lack sufficient knowledge of their physiological ecology to determine requirements for survival now and in the face of climate change. We measured resting and active metabolic rates of giant pandas in order to determine if current bamboo resources were sufficient for adding additional animals to populations in natural reserves. Resting metabolic rates were somewhat below average for a panda sized mammal and active metabolic rates were in the normal range. Pandas do not have exceptionally low metabolic rates. Nevertheless, there is enough bamboo in natural reserves to support both natural populations and large numbers of reintroduced pandas. Bamboo will not be the limiting factor in successful reintroduction. PMID:27264109

Gastric dilatation and volvulus in a red panda (Ailurus fulgens).

Science.gov (United States)

Neilsen, Colleen; Mans, Christoph; Colopy, Sara A

2014-11-01

To describe the successful management of gastric dilatation and volvulus (GDV) in a red panda. Clinical report. Red panda diagnosed with GDV. A 12-year-old male red panda (Ailurus fulgens) was evaluated for acute onset inappetence, staggering, collapse, and tachypnea. Gastric dilatation and volvulus (GDV) was diagnosed by radiography, abdominal ultrasonography, and exploratory celiotomy. Torsion of the stomach was corrected and an incisional gastropexy performed to prevent recurrence. No organs were devitalized, no other abnormalities detected, and the red panda recovered fully within 72 hours. GDV should be considered as a differential diagnosis for red pandas presenting with acute onset of unspecific signs such as collapse, inappetence, and abdominal distension. GDV in red pandas can be diagnosed and successfully treated as described in dogs. © Copyright 2014 by The American College of Veterinary Surgeons.

Status and Evolution of ATLAS Workload Management System PanDA

CERN Document Server

AUTHOR|(CDS)2067365; The ATLAS collaboration

2012-01-01

The ATLAS experiment at the LHC uses a sophisticated workload management system, PanDA, to provide access for thousands of physicists to distributed computing resources of unprecedented scale. This system has proved to be robust and scalable during three years of LHC operations. We describe the design and performance of PanDA in ATLAS. The features which make PanDA successful in ATLAS could be applicable to other exabyte scale scientific projects. We describe plans to evolve PanDA towards a general workload management system for the new BigData initiative announced by the US government. Other planned future improvements to PanDA will also be described

PANDA-A novel instrument for non-destructive sample analysis

International Nuclear Information System (INIS)

Turunen, Jani; Peraejaervi, Kari; Poellaenen, Roy; Toivonen, Harri

2010-01-01

An instrument known as PANDA (Particles And Non-Destructive Analysis) for non-destructive sample analysis has been designed and built at the Finnish Radiation and Nuclear Safety Authority (STUK). In PANDA the measurement techniques and instruments designed for the basic research are applied to the analysis of environmental samples. PANDA has two vacuum chambers, one for loading samples and the other for measurements. In the measurement chamber there are two individual measurement positions. Currently the first one hosts an HPGe gamma detector and a position-sensitive alpha detector. The second measurement position is intended for precise characterization of found particles. PANDA's data are recorded in event mode and events are timestamped. In the present article the technical design of PANDA is presented in detail. In addition, its performance using depleted uranium particles and an air filter is demonstrated.

Jagannath Panda

Indian Academy of Sciences (India)

Home; Journals; Journal of Chemical Sciences. Jagannath Panda. Articles written in Journal of Chemical Sciences. Volume 112 Issue 6 December 2000 pp 615-622 Physical and Theoretical. Kinetic investigation of the oxidation of N-alkyl anilines by peroxomonophosphoric acid in anionic surfactant sodium lauryl sulphate.

The PANDA Barrel DIRC detector

International Nuclear Information System (INIS)

Hoek, M.; Dzhygadlo, R.; Gerhardt, A.; Götzen, K.; Hohler, R.; Kalicy, G.; Kumawat, H.; Lehmann, D.; Lewandowski, B.; Patsyuk, M.; Peters, K.; Schepers, G.; Schmitt, L.; Schwarz, C.; Schwiening, J.; Traxler, M.; Zühlsdorf, M.; Dodokhov, V. Kh.; Britting, A.; Eyrich, W.

2014-01-01

The PANDA experiment at the new Facility for Antiproton and Ion Research in Europe (FAIR) at GSI, Darmstadt, will study fundamental questions of hadron physics and QCD using high-intensity cooled antiproton beams with momenta between 1.5 and 15 GeV/c. Efficient Particle Identification for a wide momentum range and the full solid angle is required for reconstructing the various physics channels of the PANDA program. Hadronic Particle Identification in the barrel region of the detector will be provided by a DIRC counter. The design is based on the successful BABAR DIRC with important improvements, such as focusing optics and fast photon timing. Several of these improvements, including different radiator geometries and optics, were tested in particle beams at GSI and at CERN. The evolution of the conceptual design of the PANDA Barrel DIRC and the performance of complex prototypes in test beam campaigns will be discussed

The PANDA Barrel DIRC detector

Energy Technology Data Exchange (ETDEWEB)

Hoek, M., E-mail: matthias.hoek@uni-mainz.de [Institut für Kernphysik, Johannes Gutenberg University Mainz, Mainz (Germany); Dzhygadlo, R.; Gerhardt, A.; Götzen, K.; Hohler, R.; Kalicy, G.; Kumawat, H.; Lehmann, D.; Lewandowski, B.; Patsyuk, M.; Peters, K.; Schepers, G.; Schmitt, L.; Schwarz, C.; Schwiening, J.; Traxler, M.; Zühlsdorf, M. [GSI Helmholtzzentrum für Schwerionenforschung GmbH, Darmstadt (Germany); Dodokhov, V. Kh. [Joint Institute for Nuclear Research, Dubna (Russian Federation); Britting, A.; Eyrich, W. [Friedrich Alexander-University of Erlangen-Nuremberg, Erlangen (Germany); and others

2014-12-01

The PANDA experiment at the new Facility for Antiproton and Ion Research in Europe (FAIR) at GSI, Darmstadt, will study fundamental questions of hadron physics and QCD using high-intensity cooled antiproton beams with momenta between 1.5 and 15 GeV/c. Efficient Particle Identification for a wide momentum range and the full solid angle is required for reconstructing the various physics channels of the PANDA program. Hadronic Particle Identification in the barrel region of the detector will be provided by a DIRC counter. The design is based on the successful BABAR DIRC with important improvements, such as focusing optics and fast photon timing. Several of these improvements, including different radiator geometries and optics, were tested in particle beams at GSI and at CERN. The evolution of the conceptual design of the PANDA Barrel DIRC and the performance of complex prototypes in test beam campaigns will be discussed.

Giant Panda habitat selection in the Foping Nature Reserve, China

NARCIS (Netherlands)

Liu, X.; Toxopeus, A.G.; Skidmore, A.K.; Shao, X.; Dang, D.; Wang, T.; Prins, H.H.T.

2005-01-01

Little is known about habitat selection of the giant panda (Ailuropoda melanoleuca), especially about the relationship between giant panda presence and bamboo and tree structures. We presented data on giant panda habitat use and selection in Foping Nature Reserve (NR), China. We used 1,066

Long Noncoding RNA PANDA Positively Regulates Proliferation of Osteosarcoma Cells.

Science.gov (United States)

Kotake, Yojiro; Goto, Taiki; Naemura, Madoka; Inoue, Yasutoshi; Okamoto, Haruna; Tahara, Keiichiro

2017-01-01

A long noncoding RNA, p21-associated ncRNA DNA damage-activated (PANDA), associates with nuclear transcription factor Y subunit alpha (NF-YA) and inhibits its binding to promoters of apoptosis-related genes, thereby repressing apoptosis in normal human fibroblasts. Here, we show that PANDA is involved in regulating proliferation in the U2OS human osteosarcoma cell line. U2OS cells were transfected with siRNAs against PANDA 72 h later and they were subjected to reverse transcription-polymerase chain reaction (RT-PCR), quantitative RT-PCR and cell-cycle analysis. PANDA was highly expressed in U2OS cells, and its expression was induced by DNA damage. Silencing PANDA caused arrest at the G 1 phase of the cell cycle, leading to inhibition of cell proliferation. Quantitative RT-PCR showed that silencing PANDA increased mRNA levels of the cyclin-dependent kinase inhibitor p18, which caused G 1 phase arrest. These results suggest that PANDA promotes G 1 -S transition by repressing p18 transcription, and thus promotes U2OS cell proliferation. Copyright© 2017 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.

Mapping and modelling the habitat of giant pandas in Foping Nature Reserve, China

OpenAIRE

Liu, X.

2001-01-01

The fact that only about 1000 giant pandas and 29500 km2 of panda habitat are left in the west part of China makes it an urgent issue to save this endangered animal species and protect its habitat. For effective conservation of the giant panda and its habitat, a thorough evaluation of panda habitat and panda-habitat relationship based on each individual panda nature reserve is necessary and important. Mapping has been an effective approach for wildlife habitat evaluation and monitoring. There...

PandaEPL: a library for programming spatial navigation experiments.

Science.gov (United States)

Solway, Alec; Miller, Jonathan F; Kahana, Michael J

2013-12-01

Recent advances in neuroimaging and neural recording techniques have enabled researchers to make significant progress in understanding the neural mechanisms underlying human spatial navigation. Because these techniques generally require participants to remain stationary, computer-generated virtual environments are used. We introduce PandaEPL, a programming library for the Python language designed to simplify the creation of computer-controlled spatial-navigation experiments. PandaEPL is built on top of Panda3D, a modern open-source game engine. It allows users to construct three-dimensional environments that participants can navigate from a first-person perspective. Sound playback and recording and also joystick support are provided through the use of additional optional libraries. PandaEPL also handles many tasks common to all cognitive experiments, including managing configuration files, logging all internal and participant-generated events, and keeping track of the experiment state. We describe how PandaEPL compares with other software for building spatial-navigation experiments and walk the reader through the process of creating a fully functional experiment.

The minimum area requirements (MAR) for giant panda: an empirical study.

Science.gov (United States)

Qing, Jing; Yang, Zhisong; He, Ke; Zhang, Zejun; Gu, Xiaodong; Yang, Xuyu; Zhang, Wen; Yang, Biao; Qi, Dunwu; Dai, Qiang

2016-12-08

Habitat fragmentation can reduce population viability, especially for area-sensitive species. The Minimum Area Requirements (MAR) of a population is the area required for the population's long-term persistence. In this study, the response of occupancy probability of giant pandas against habitat patch size was studied in five of the six mountain ranges inhabited by giant panda, which cover over 78% of the global distribution of giant panda habitat. The probability of giant panda occurrence was positively associated with habitat patch area, and the observed increase in occupancy probability with patch size was higher than that due to passive sampling alone. These results suggest that the giant panda is an area-sensitive species. The MAR for giant panda was estimated to be 114.7 km 2 based on analysis of its occupancy probability. Giant panda habitats appear more fragmented in the three southern mountain ranges, while they are large and more continuous in the other two. Establishing corridors among habitat patches can mitigate habitat fragmentation, but expanding habitat patch sizes is necessary in mountain ranges where fragmentation is most intensive.

The Straw Tube Trackers of the PANDA Experiment

International Nuclear Information System (INIS)

Gianotti, P.; Lucherini, V.; Pace, E.; Boca, G.L.; Costanza, S.; Genova, P.; Lavezzi, L.; Montanga, P.; Rotondi, A.; Bragadireanu, M.; Vasile, M.E.; Pietreanu, D.; Biernat, J.; Jowzaee, S.; Korcyl, G.; Palka, M.; Salabura, P.; Smyrski, J.; Fiutowski, T.; Idzik, M.; Przyborowski, D.; Korcyl, K.; Kulessa, P.; Pysz, K.; Dobbs, S.; Tomaradze, A.; Bettoni, D.; Fioravanti, E.; Garzia, I.; Savrie, M.; Kozlov, V.; Mertens, M.; Ohm, H.; Orfanitski, S.; Ritman, J.; Serdyuk, V.; Wintz, P.; Spataro, S.

2013-06-01

The PANDA experiment will be built at the FAIR facility at Darmstadt (Germany) to perform accurate tests of the strong interaction through p-bar p and p-bar A annihilation's studies. To track charged particles, two systems consisting of a set of planar, closed-packed, self-supporting straw tube layers are under construction. The PANDA straw tubes will have also unique characteristics in term of material budget and performance. They consist of very thin mylar-aluminized cathodes which are made self-supporting by means of the operation gas-mixture over-pressure. This solution allows to reduce at maximum the weight of the mechanical support frame and hence the detector material budget. The PANDA straw tube central tracker will not only reconstruct charged particle trajectories, but also will help in low momentum (< 1 GeV) particle identification via dE/dx measurements. This is a quite new approach that PANDA tracking group has first tested with detailed Monte Carlo simulations, and then with experimental tests of detector prototypes. This paper addresses the design issues of the PANDA straw tube trackers and the performance obtained in prototype tests. (authors)

Online tracking with GPUs at the PANDA experiment

Energy Technology Data Exchange (ETDEWEB)

Bianchi, Ludovico; Herten, Andreas; Ritman, James; Stockmanns, Tobias [Forschungszentrum Juelich (Germany); Collaboration: PANDA-Collaboration

2015-07-01

The PANDA experiment is a next generation particle detector planned for operation at the FAIR facility, that will study collisions of antiprotons with beam momenta of 1.5-15 GeV/c on a fixed proton target. Signal and background events at PANDA will look very similar, making a conventional hardware-trigger based approach unfeasible. Instead, data coming from the detector are acquired continuously, and event selection is performed in real time. A rejection factor of up to 1000 is needed to reduce the data rate for offline storage, making the data acquisition system computationally very challenging. Our activity within the PANDA collaboration is centered on the development and implementation of particle tracking algorithms on Graphical Processing Units (GPUs), and on studying the possibility of performing tracking for online event filtering using a multi-GPU architecture. Three algorithms are currently being developed, using information from the PANDA tracking system: a Hough Transform, a Riemann Track Finder, and a Triplet Finder algorithm. This talk presents the algorithms, their performance, and studies for GPU data transfer methods based on so-called message queues for a deeper integration of the algorithms with the FairRoot and PandaRoot frameworks.

Whole-genome sequencing of giant pandas provides insights into demographic history and local adaptation

DEFF Research Database (Denmark)

Zhao, Shancen; Zheng, Pingping; Dong, Shanshan

2013-01-01

The panda lineage dates back to the late Miocene and ultimately leads to only one extant species, the giant panda (Ailuropoda melanoleuca). Although global climate change and anthropogenic disturbances are recognized to shape animal population demography their contribution to panda population...... dynamics remains largely unknown. We sequenced the whole genomes of 34 pandas at an average 4.7-fold coverage and used this data set together with the previously deep-sequenced panda genome to reconstruct a continuous demographic history of pandas from their origin to the present. We identify two...... panda populations that show genetic adaptation to their environments. However, in all three populations, anthropogenic activities have negatively affected pandas for 3,000 years....

Hospital y casa del médico

Directory of Open Access Journals (Sweden)

Zevaco, J. F.

1958-05-01

Full Text Available En la villa de Ben-Slimane, conocida hasta hace poco tiempo por Boulhaut, se ha construido un nuevo hospital cuya arquitectura acusa el carácter íntimo de su reducido programa. A pocos metros del edificio hospitalario se eleva la vivienda del médico-jefe, resuelta en armonía con él.

Evolution of the ATLAS PanDA Workload Management System for Exascale Computational Science

CERN Document Server

Maeno, T; The ATLAS collaboration; Klimentov, A; Nilsson, P; Oleynik, D; Panitkin, S; Petrosyan, A; Schovancova, J; Vaniachine, A; Wenaus, T; Yu, D

2013-01-01

An important foundation underlying the impressive success of data processing and analysis in the ATLAS experiment [1] at the LHC [2] is the Production and Distributed Analysis (PanDA) workload management system [3]. PanDA was designed specifically for ATLAS and proved to be highly successful in meeting all the distributed computing needs of the experiment. However, the core design of PanDA is not experiment specific. The PanDA workload management system is capable of meeting the needs of other data intensive scientific applications. Alpha-Magnetic Spectrometer [4], an astro-particle experiment on the International Space Station, and the Compact Muon Solenoid [5], an LHC experiment, have successfully evaluated PanDA and are pursuing its adoption. In this paper, a description of the new program of work to develop a generic version of PanDA will be given, as well as the progress in extending PanDA's capabilities to support supercomputers and clouds and to leverage intelligent networking. PanDA has demonstrated a...

Evolution of the ATLAS PanDA Workload Management System for Exascale Computational Science

CERN Document Server

Maeno, T; The ATLAS collaboration; Klimentov, A; Nilsson, P; Oleynik, D; Panitkin, S; Petrosyan, A; Schovancova, J; Vaniachine, A; Wenaus, T; Yu, D

2014-01-01

An important foundation underlying the impressive success of data processing and analysis in the ATLAS experiment [1] at the LHC [2] is the Production and Distributed Analysis (PanDA) workload management system [3]. PanDA was designed specifically for ATLAS and proved to be highly successful in meeting all the distributed computing needs of the experiment. However, the core design of PanDA is not experiment specific. The PanDA workload management system is capable of meeting the needs of other data intensive scientific applications. Alpha-Magnetic Spectrometer [4], an astro-particle experiment on the International Space Station, and the Compact Muon Solenoid [5], an LHC experiment, have successfully evaluated PanDA and are pursuing its adoption. In this paper, a description of the new program of work to develop a generic version of PanDA will be given, as well as the progress in extending PanDA's capabilities to support supercomputers and clouds and to leverage intelligent networking. PanDA has demonstrated a...

Factors affecting genotyping success in giant panda fecal samples.

Science.gov (United States)

Zhu, Ying; Liu, Hong-Yi; Yang, Hai-Qiong; Li, Yu-Dong; Zhang, He-Min

2017-01-01

Fecal samples play an important role in giant panda conservation studies. Optimal preservation conditions and choice of microsatellites for giant panda fecal samples have not been established. In this study, we evaluated the effect of four factors (namely, storage type (ethanol (EtOH), EtOH -20 °C, 2-step storage medium, DMSO/EDTA/Tris/salt buffer (DETs) and frozen at -20 °C), storage time (one, three and six months), fragment length, and repeat motif of microsatellite loci) on the success rate of microsatellite amplification, allelic dropout (ADO) and false allele (FA) rates from giant panda fecal samples. Amplification success and ADO rates differed between the storage types. Freezing was inferior to the other four storage methods based on the lowest average amplification success and the highest ADO rates ( P panda fecal preservation in microsatellite studies, and EtOH and the 2-step storage medium should be chosen on priority for long-term storage. We recommend candidate microsatellite loci with longer repeat motif to ensure greater genotyping success for giant panda fecal studies.

Computing Activities for the PANDA Experiment at FAIR

NARCIS (Netherlands)

Messchendorp, Johan; Gruntorad, J; Lokajicek, M

2010-01-01

The PANDA experiment at the future facility FAIR will provide valuable data for our present understanding of the strong interaction. In preparation for the experiments, large-scale simulations for design and feasibility studies are performed exploiting a new software framework, PandaROOT, which is

Feasibility Studies for the PANDA Experiment at FAIR

NARCIS (Netherlands)

Biegun, A.

PANDA, the detector to study AntiProton ANnihilations at DArmstadt, will be installed at the future international Facility for Anti-proton and Ion Research (FAIR) in Darmstadt, Germany. The PANDA physics program is oriented towards the studies of the strong interaction and hadron structure performed

FEASIBILITY STUDIES FOR THE PANDA EXPERIMENT AT FAIR

NARCIS (Netherlands)

Biegun, A.

PANDA, the detector to study AntiProton ANnihilations at DArmstadt, will be installed at the future international Facility for Anti-proton and Ion Research (FAIR) in Darmstadt, Germany. The PANDA physics program is oriented towards the studies of the strong interaction and hadron structure performed

Metabolic rate of the red panda, Ailurus fulgens, a dietary bamboo specialist.

Science.gov (United States)

Fei, Yuxiang; Hou, Rong; Spotila, James R; Paladino, Frank V; Qi, Dunwu; Zhang, Zhihe

2017-01-01

The red panda (Ailurus fulgens) has a similar diet, primarily bamboo, and shares the same habitat as the giant panda, Ailuropoda melanoleuca. There are considerable efforts underway to understand the ecology of the red panda and to increase its populations in natural reserves. Yet it is difficult to design an effective strategy for red panda reintroduction if we do not understand its basic biology. Here we report the resting metabolic rate of the red panda and find that it is higher than previously measured on animals from a zoo. The resting metabolic rate was 0.290 ml/g/h (range 0.204-0.342) in summer and 0.361 ml/g/h in winter (range 0.331-0.406), with a statistically significant difference due to season and test temperature. Temperatures in summer were probably within the thermal neutral zone for metabolism but winter temperatures were below the thermal neutral zone. There was no difference in metabolic rate between male and female red pandas and no difference due to mass. Our values for metabolic rate were much higher than those measured by McNab for 2 red pandas from a zoo. The larger sample size (17), more natural conditions at the Panda Base and improved accuracy of the metabolic instruments provided more accurate metabolism measurements. Contrary to our expectations based on their low quality bamboo diet, the metabolic rates of red pandas were similar to mammals of the same size. Based on their metabolic rates red pandas would not be limited by their food supply in natural reserves.

Metabolic rate of the red panda, Ailurus fulgens, a dietary bamboo specialist.

Directory of Open Access Journals (Sweden)

Yuxiang Fei

Full Text Available The red panda (Ailurus fulgens has a similar diet, primarily bamboo, and shares the same habitat as the giant panda, Ailuropoda melanoleuca. There are considerable efforts underway to understand the ecology of the red panda and to increase its populations in natural reserves. Yet it is difficult to design an effective strategy for red panda reintroduction if we do not understand its basic biology. Here we report the resting metabolic rate of the red panda and find that it is higher than previously measured on animals from a zoo. The resting metabolic rate was 0.290 ml/g/h (range 0.204-0.342 in summer and 0.361 ml/g/h in winter (range 0.331-0.406, with a statistically significant difference due to season and test temperature. Temperatures in summer were probably within the thermal neutral zone for metabolism but winter temperatures were below the thermal neutral zone. There was no difference in metabolic rate between male and female red pandas and no difference due to mass. Our values for metabolic rate were much higher than those measured by McNab for 2 red pandas from a zoo. The larger sample size (17, more natural conditions at the Panda Base and improved accuracy of the metabolic instruments provided more accurate metabolism measurements. Contrary to our expectations based on their low quality bamboo diet, the metabolic rates of red pandas were similar to mammals of the same size. Based on their metabolic rates red pandas would not be limited by their food supply in natural reserves.

Impacts of temperature on giant panda habitat in the north Minshan Mountains.

Science.gov (United States)

Liu, Gang; Guan, Tianpei; Dai, Qiang; Li, Huixin; Gong, Minghao

2016-02-01

Understanding the impacts of meteorological factors on giant pandas is necessary for future conservation measures in response to global climate change. We integrated temperature data with three main habitat parameters (elevation, vegetation type, and bamboo species) to evaluate the influence of climate change on giant panda habitat in the northern Minshan Mountains using a habitat assessment model. Our study shows that temperature (relative importance = 25.1%) was the second most important variable influencing giant panda habitat excepting the elevation. There was a significant negative correlation between temperature and panda presence (ρ = -0.133, P pandas within the study area was 18-21°C, followed by 15-17°C and 22-24°C. The overall suitability of giant panda habitats will increase by 2.7%, however, it showed a opposite variation patterns between the eastern and northwestern region of the study area. Suitable and subsuitable habitats in the northwestern region of the study area, which is characterized by higher elevation and latitude, will increase by 18007.8 hm(2) (9.8% habitat suitability), while the eastern region will suffer a decrease of 9543.5 hm(2) (7.1% habitat suitability). Our results suggest that increasing areas of suitable giant panda habitat will support future giant panda expansion, and food shortage and insufficient living space will not arise as problems in the northwest Minshan Mountains, which means that giant pandas can adapt to climate change, and therefore may be resilient to climate change. Thus, for the safety and survival of giant pandas in the Baishuijiang Reserve, we propose strengthening the giant panda monitoring program in the west and improving the integrity of habitats to promote population dispersal with adjacent populations in the east.

Slab-coupled optical sensor fabrication using side-polished Panda fibers.

Science.gov (United States)

King, Rex; Seng, Frederick; Stan, Nikola; Cuzner, Kevin; Josephson, Chad; Selfridge, Richard; Schultz, Stephen

2016-11-01

A new device structure used for slab-coupled optical sensor (SCOS) technology was developed to fabricate electric field sensors. This new device structure replaces the D-fiber used in traditional SCOS technology with a side-polished Panda fiber. Unlike the D-fiber SCOS, the Panda fiber SCOS is made from commercially available materials and is simpler to fabricate. The Panda SCOS interfaces easier with lab equipment and exhibits ∼3  dB less loss at link points than the D-fiber SCOS. The optical system for the D-fiber is bandwidth limited by a transimpedance amplifier (TIA) used to amplify to the electric signal. The Panda SCOS exhibits less loss than the D-fiber and, as a result, does not require as high a gain setting on the TIA, which results in an overall higher bandwidth range. Results show that the Panda sensor also achieves comparable sensitivity results to the D-fiber SCOS. Although the Panda SCOS is not as sensitive as other side-polished fiber electric field sensors, it can be fabricated much easier because the fabrication process does not require special alignment techniques, and it is made from commercially available materials.

Resting site use of giant pandas in Wanglang Nature Reserve.

Science.gov (United States)

Kang, Dongwei; Wang, Xiaorong; Li, Junqing

2017-10-23

Little is known about the resting sites used by the giant panda (Ailuropoda melanoleuca), which restricts our understanding of their resting habits and limits conservation efforts. To enhance our understanding of resting site requirements and factors affecting the resting time of giant pandas, we investigated the characteristics of resting sites in the Wanglang Nature Reserve, Sichuan Province, China. The results indicated that the resting sites of giant pandas were characterised by a mean slope of 21°, mean nearest tree size of 53.75 cm, mean nearest shrub size of 2.82 cm, and mean nearest bamboo number of 56. We found that the resting sites were closer to bamboo than to trees and shrubs, suggesting that the resting site use of giant pandas is closely related to the presence of bamboo. Considering that giant pandas typically rest near a large-sized tree, protection of large trees in the forests is of considerable importance for the conservation of this species. Furthermore, slope was found to be an important factor affecting the resting time of giant pandas, as they tended to rest for a relatively longer time in sites with a smaller degree of slope.

PANDA: a pipeline toolbox for analyzing brain diffusion images

Directory of Open Access Journals (Sweden)

Zaixu eCui

2013-02-01

Full Text Available Diffusion magnetic resonance imaging (dMRI is widely used in both scientific research and clinical practice in in-vivo studies of the human brain. While a number of post-processing packages have been developed, fully automated processing of dMRI datasets remains challenging. Here, we developed a MATLAB toolbox named Pipeline for Analyzing braiN Diffusion imAges (PANDA for fully automated processing of brain diffusion images. The processing modules of a few established packages, including FMRIB Software Library (FSL, Pipeline System for Octave and Matlab (PSOM, Diffusion Toolkit and MRIcron, were employed in PANDA. Using any number of raw dMRI datasets from different subjects, in either DICOM or NIfTI format, PANDA can automatically perform a series of steps to process DICOM/NIfTI to diffusion metrics (e.g., FA and MD that are ready for statistical analysis at the voxel-level, the atlas-level and the Tract-Based Spatial Statistics (TBSS-level and can finish the construction of anatomical brain networks for all subjects. In particular, PANDA can process different subjects in parallel, using multiple cores either in a single computer or in a distributed computing environment, thus greatly reducing the time cost when dealing with a large number of datasets. In addition, PANDA has a friendly graphical user interface (GUI, allowing the user to be interactive and to adjust the input/output settings, as well as the processing parameters. As an open-source package, PANDA is freely available at http://www.nitrc.org/projects/panda/. This novel toolbox is expected to substantially simplify the image processing of dMRI datasets and facilitate human structural connectome studies.

PANDA: a pipeline toolbox for analyzing brain diffusion images.

Science.gov (United States)

Cui, Zaixu; Zhong, Suyu; Xu, Pengfei; He, Yong; Gong, Gaolang

2013-01-01

Diffusion magnetic resonance imaging (dMRI) is widely used in both scientific research and clinical practice in in-vivo studies of the human brain. While a number of post-processing packages have been developed, fully automated processing of dMRI datasets remains challenging. Here, we developed a MATLAB toolbox named "Pipeline for Analyzing braiN Diffusion imAges" (PANDA) for fully automated processing of brain diffusion images. The processing modules of a few established packages, including FMRIB Software Library (FSL), Pipeline System for Octave and Matlab (PSOM), Diffusion Toolkit and MRIcron, were employed in PANDA. Using any number of raw dMRI datasets from different subjects, in either DICOM or NIfTI format, PANDA can automatically perform a series of steps to process DICOM/NIfTI to diffusion metrics [e.g., fractional anisotropy (FA) and mean diffusivity (MD)] that are ready for statistical analysis at the voxel-level, the atlas-level and the Tract-Based Spatial Statistics (TBSS)-level and can finish the construction of anatomical brain networks for all subjects. In particular, PANDA can process different subjects in parallel, using multiple cores either in a single computer or in a distributed computing environment, thus greatly reducing the time cost when dealing with a large number of datasets. In addition, PANDA has a friendly graphical user interface (GUI), allowing the user to be interactive and to adjust the input/output settings, as well as the processing parameters. As an open-source package, PANDA is freely available at http://www.nitrc.org/projects/panda/. This novel toolbox is expected to substantially simplify the image processing of dMRI datasets and facilitate human structural connectome studies.

PANDA passive decay heat removal transient test results

International Nuclear Information System (INIS)

Bandurski, Th.; Dreier, J.; Huggenberger, M.

1997-01-01

PANDA is a large scale facility for investigating the long-term decay heat removal from the containment of a next generation of 'passive' Advanced Light Water Reactors (ALWR). PANDA was used to examine the long-term LOCA response of the Passive Containment Cooling System (PCCS) for the General Electric (GE) Simplified Boiling Water Reactor (SBWR). The first PANDA test series had the dual objectives of demonstrating the performance of the SBWR PCCS and extending the data base available for containment analysis code qualification. The test objectives also include the study of the effects of mixing and stratification of steam and noncondensible gases in the drywell (DW) and in the suppression chamber or wetwell (WW). Ten tests were conducted in the course of the PANDA SBWR Program. The tests demonstrated a favorable and robust overall PCCS performance under different conditions. The present paper focuses on the main phenomena observed during the tests with respect to PCCS operation and DW gas mixing. (author)

Feasibility study of a transversely polarized target in PANDA

Energy Technology Data Exchange (ETDEWEB)

Froehlich, Bertold [Helmholtz Institut Mainz (Germany)

2014-07-01

PANDA (Antiproton Annihilation at Darmstadt) is a key project at the Facility for Antiproton and Ion Research (FAIR), currently under construction at the GSI Darmstadt. PANDA is a state of the art detector for antiproton-proton fixed target experiments. A transversely polarized target in PANDA would allow the determination of the proton electromagnetic form factors in the time-like region with unprecedented accuracy and the first-time extraction of their imaginary part, opening a new window for investigating the nucleon structure. As a first step for achieving a transverse target polarization, the target region has to be shielded against the 2 T longitudinal magnetic flux from the solenoid of the PANDA spectrometer. We present numerical simulations and experimental results on intense magnetic flux shielding using a high temperature superconducting hollow cylinder.

Panda, Prof. Sudhakar

Indian Academy of Sciences (India)

Fellow Profile. Elected: 2017 Section: Physics. Panda, Prof. Sudhakar Ph.D. (IoP, Bhubaneswar), FNA, FNASc. Date of birth: 23 February 1959. Specialization: High Energy Physics, String Theory, Cosmology, Quantum Field Theory Address: Director, Institute of Physics, Sachivalaya Marg, Bhubaneswar 751 005, Orissa

Mapping and modelling the habitat of giant pandas in Foping Nature Reserve, China

NARCIS (Netherlands)

Liu, X.

2001-01-01

The fact that only about 1000 giant pandas and 29500 km2 of panda habitat are left in the west part of China makes it an urgent issue to save this endangered animal species and protect its habitat. For effective conservation of the giant panda and its habitat, a thorough evaluation of panda habitat

Seasonal changes of progesterone and testosterone contents in hair of giant pandas

International Nuclear Information System (INIS)

Guo Dazhi; Liu Xianyi; Chen Faju

1994-01-01

Seasonal changes of progesterone content (PSC) in hair of three female giant pandas and testosterone content (TSC) in hair of two male giant pandas were tested by radioimmunoassay. During March to early June, PSC in two non-pregnant giant pandas (x-bar+-SD = 13.40 +- 10.06 and 10.60 +- 8.88 ng/g hair respectively) were higher than those in non-breeding season (3.07 +-1.07 and 3.20 +- 1.15 ng/g, P<0.01). PSC in a 18-year-old female giant panda remained at low levels (2.72 +- 1.49 ng/g) during March to December. In a twin-bear giant panda, PSC (6.77 +- 3.66 ng/g) appeared higher than that in non-pregnant giant pandas in non-breeding season. Around February to the end of May, TSC in two male giant pandas (1.89 +- 1.71 and 1.82 +- 1.04 ng/g respectively) were also higher than that in non-breeding season (0.98 +- 0.57 and 0.75 +- 0.39 ng/g, P<0.01). the findings from the study implied that giant panda's hair is possible to be used as a specimen to carry out steroids research in the endangered species

Amdoparvovirus Infection in Red Pandas ( Ailurus fulgens).

Science.gov (United States)

Alex, Charles E; Kubiski, Steven V; Li, Linlin; Sadeghi, Mohammadreza; Wack, Raymund F; McCarthy, Megan A; Pesavento, Joseph B; Delwart, Eric; Pesavento, Patricia A

2018-01-01

Aleutian mink disease virus is the type species in the genus Amdoparvovirus, and in mink and other Mustelidae can cause either subclinical disease or fatal chronic immune stimulation and immune complex disease. The authors describe a novel amdoparvovirus in the endangered red panda ( Ailurus fulgens), discovered using viral metagenomics. The authors analyzed the prevalence, tissue distribution, and disease association by PCR, in situ hybridization, electron microscopy, and histology in a group of 6 red pandas from a single zoological collection. The study incorporates a fecal shedding survey and analysis of tissues from 4 necropsied animals over a 12-year span. The tentatively named red panda amdoparvovirus (RpAPV) was detected in the feces and/or tissues of all animals tested. At necropsy of 1 geriatric animal, infection was associated with pyogranulomatous peritonitis, pancreatitis, and myocarditis. Other animals had detectable low-level viral nucleic acid in lymph nodes and both oral and intestinal epithelium at the time of necropsy. Full-length genome sequences of RpAPV strains from 2 animals had 12% sequence divergence, demonstrating genetic diversity even among in-contact animals. RpAPV is a persistent infection in this cohort of red pandas, and has variable clinical expression.

PanDA Beyond ATLAS: Workload Management for Data Intensive Science

CERN Document Server

Schovancova, J; The ATLAS collaboration; Klimentov, A; Maeno, T; Nilsson, P; Oleynik, D; Panitkin, S; Petrosyan, A; Vaniachine, A; Wenaus, T; Yu, D

2013-01-01

The PanDA Production ANd Distributed Analysis system has been developed by ATLAS to meet the experiment's requirements for a data-driven workload management system for production and distributed analysis processing capable of operating at LHC data processing scale. After 7 years of impressively successful PanDA operation in ATLAS there are also other experiments which can benefit from PanDA in the Big Data challenge, with several at various stages of evaluation and adoption. The new project "Next Generation Workload Management and Analysis System for Big Data" is extending PanDA to meet the needs of other data intensive scientific applications in HEP, astro-particle and astrophysics communities, bio-informatics and other fields as a general solution to large scale workload management. PanDA can utilize dedicated or opportunistic computing resources such as grids, clouds, and High Performance Computing facilities, and is being extended to leverage next generation intelligent networks in automated workflow mana...

amiya kumar panda

Indian Academy of Sciences (India)

Home; Journals; Journal of Chemical Sciences. AMIYA KUMAR PANDA. Articles written in Journal of Chemical Sciences. Volume 130 Issue 4 April 2018 pp 42. Role of PEG 2000 in the surface modification and physicochemical characteristics of pyrazinamide loaded nanostructured lipid carriers · GOURAB KARMAKAR ...

S K Panda

Indian Academy of Sciences (India)

Home; Journals; Sadhana. S K Panda. Articles written in Sadhana. Volume 37 Issue 2 April 2012 pp 223-240. Multi-objective parametric optimization of powder mixed electro-discharge machining using response surface methodology and non-dominated sorting genetic algorithm · Soumyakant Padhee Niharranjan Nayak ...

Tarun K Panda

Indian Academy of Sciences (India)

Tarun K Panda. Articles written in Journal of Chemical Sciences. Volume 126 Issue 5 September 2014 pp 1463-1475 Special issue on Chemical Crystallography. Synthesis of monomeric and polymeric alkali and alkaline earth metal complexes using a phosphinoselenoic amide ligand in metal coordination sphere.

Experience with ATLAS MySQL PanDA database service

International Nuclear Information System (INIS)

Smirnov, Y; Wlodek, T; Hover, J; Smith, J; Wenaus, T; Yu, D; De, K; Ozturk, N

2010-01-01

The PanDA distributed production and analysis system has been in production use for ATLAS data processing and analysis since late 2005 in the US, and globally throughout ATLAS since early 2008. Its core architecture is based on a set of stateless web services served by Apache and backed by a suite of MySQL databases that are the repository for all PanDA information: active and archival job queues, dataset and file catalogs, site configuration information, monitoring information, system control parameters, and so on. This database system is one of the most critical components of PanDA, and has successfully delivered the functional and scaling performance required by PanDA, currently operating at a scale of half a million jobs per week, with much growth still to come. In this paper we describe the design and implementation of the PanDA database system, its architecture of MySQL servers deployed at BNL and CERN, backup strategy and monitoring tools. The system has been developed, thoroughly tested, and brought to production to provide highly reliable, scalable, flexible and available database services for ATLAS Monte Carlo production, reconstruction and physics analysis.

Experience with ATLAS MySQL PanDA database service

Energy Technology Data Exchange (ETDEWEB)

Smirnov, Y; Wlodek, T; Hover, J; Smith, J; Wenaus, T; Yu, D [Physics Department, Brookhaven National Laboratory, Upton, NY 11973-5000 (United States); De, K; Ozturk, N [Department of Physics, University of Texas at Arlington, Arlington, TX, 76019 (United States)

2010-04-01

The PanDA distributed production and analysis system has been in production use for ATLAS data processing and analysis since late 2005 in the US, and globally throughout ATLAS since early 2008. Its core architecture is based on a set of stateless web services served by Apache and backed by a suite of MySQL databases that are the repository for all PanDA information: active and archival job queues, dataset and file catalogs, site configuration information, monitoring information, system control parameters, and so on. This database system is one of the most critical components of PanDA, and has successfully delivered the functional and scaling performance required by PanDA, currently operating at a scale of half a million jobs per week, with much growth still to come. In this paper we describe the design and implementation of the PanDA database system, its architecture of MySQL servers deployed at BNL and CERN, backup strategy and monitoring tools. The system has been developed, thoroughly tested, and brought to production to provide highly reliable, scalable, flexible and available database services for ATLAS Monte Carlo production, reconstruction and physics analysis.

The Lushan earthquake and the giant panda: impacts and conservation.

Science.gov (United States)

Zhang, Zejun; Yuan, Shibin; Qi, Dunwu; Zhang, Mingchun

2014-06-01

Earthquakes not only result in a great loss of human life and property, but also have profound effects on the Earth's biodiversity. The Lushan earthquake occurred on 20 Apr 2013, with a magnitude of 7.0 and an intensity of 9.0 degrees. A distance of 17.0 km from its epicenter to the nearest distribution site of giant pandas recorded in the Third National Survey was determined. Making use of research on the Wenchuan earthquake (with a magnitude of 8.0), which occurred approximately 5 years ago, we briefly analyze the impacts of the Lushan earthquake on giant pandas and their habitat. An earthquake may interrupt ongoing behaviors of giant pandas and may also cause injury or death. In addition, an earthquake can damage conservation facilities for pandas, and result in further habitat fragmentation and degradation. However, from a historical point of view, the impacts of human activities on giant pandas and their habitat may, in fact, far outweigh those of natural disasters such as earthquakes. Measures taken to promote habitat restoration and conservation network reconstruction in earthquake-affected areas should be based on requirements of giant pandas, not those of humans. © 2013 International Society of Zoological Sciences, Institute of Zoology/Chinese Academy of Sciences and Wiley Publishing Asia Pty Ltd.

The "double panda" sign in Leigh disease.

Science.gov (United States)

Sonam, Kothari; Bindu, P S; Gayathri, Narayanappa; Khan, Nahid Akhtar; Govindaraju, C; Arvinda, Hanumanthapura R; Nagappa, Madhu; Sinha, Sanjib; Thangaraj, K; Taly, Arun B

2014-07-01

Although the "face of the giant panda" sign on magnetic resonance imaging (MRI) is traditionally considered to be characteristic of Wilson disease, it has also been reported in other metabolic disorders. This study describes the characteristic "giant panda" sign on MRI in a child with Leigh disease. The diagnosis was based on the history of neurological regression; examination findings of oculomotor abnormalities, hypotonia, and dystonia; raised serum lactate levels; and characteristic brain stem and basal ganglia signal changes on MRI. The midbrain and pontine tegmental signal changes were consistent with the "face of the giant panda and her cub" sign. In addition to Wilson disease, metabolic disorders such as Leigh disease should also be considered in the differential diagnosis of this rare imaging finding. © The Author(s) 2013.

Habitat correlates of the red panda in the temperate forests of Bhutan.

Directory of Open Access Journals (Sweden)

Sangay Dorji

Full Text Available Anthropogenic activities and associated global climate change are threatening the biodiversity in the Himalayas against a backdrop of poor knowledge of the region's threatened species. The red panda (Ailurus fulgens is a threatened mammal confined to the eastern Himalayas, and because of Bhutan's central location in the distributional range of red pandas, its forests are integral to the long-term viability of wild populations. Detailed habitat requirements of the red panda are largely speculative, and there is virtually no ecological information available on this species in Bhutan. Between 2007 and 2009, we established 615 presence/absence plots in a systematic sampling of resident habitat types within Jigme Dorji and Thrumshingla National Parks, Bhutan, to investigate broad and fine-scale red panda habitat associations. Additional locality records of red pandas were obtained from interviewing 664 park residents. Red pandas were generally confined to cool broadleaf and conifer forests from 2,110-4,389 m above sea level (asl, with the majority of records between 2,400-3,700 m asl on south and east-facing slopes. At a finer scale, multivariate analysis revealed that red pandas were strongly associated with old growth Bhutan Fir (Abies densa forest dominated by a dense cover of Yushania and Arundanaria bamboo with a high density of fallen logs and tree stumps at ground level; a high density of trees, dead snags, and rhododendron shrubs in the mid-storey; and locations that were close to water. Because Bhutan's temperate forests that encompass prime red panda habitat are also integral to human subsistence and socio-economic development, there exists an inadvertent conflict between the needs of people and red pandas. As such, careful sustainable management of Bhutan's temperate forests is necessary if a balance is to be met between the socioeconomic needs of people and the conservation goals for red pandas.

Establishment and cryopreservation of a giant panda skeletal muscle-derived cell line.

Science.gov (United States)

Yu, Fang-Jian; Zeng, Chang-Jun; Zhang, Yan; Wang, Cheng-Dong; Xiong, Tie-Yi; Fang, Sheng-Guo; Zhang, He-Min

2015-06-01

The giant panda Ailuropoda melanoleuca is an endangered species and is a symbol for wildlife conservation. Although efforts have been made to protect this rare and endangered species through breeding and conservative biology, the long-term preservation of giant panda genome resources (gametes, tissues, organs, genomic libraries, etc.) is still a practical option. In this study, the giant panda skeletal muscle-derived cell line was successfully established via primary explants culture and cryopreservation techniques. The population doubling time of giant panda skeletal cells was approximately 33.8 h, and this population maintained a high cell viability before and after cryopreservation (95.6% and 90.7%, respectively). The two skeletal muscle-specific genes SMYD1 and MYF6 were expressed and detected by RT-PCR in the giant panda skeletal muscle-derived cell line. Karyotyping analysis revealed that the frequencies of giant panda skeletal muscle cells showing a chromosome number of 2n=42 ranged from 90.6∼94.2%. Thus, the giant panda skeletal muscle-derived cell line provides a vital resource and material platform for further studies and is likely to be useful for the protection of this rare and endangered species.

Integration of Panda Workload Management System with supercomputers

Science.gov (United States)

De, K.; Jha, S.; Klimentov, A.; Maeno, T.; Mashinistov, R.; Nilsson, P.; Novikov, A.; Oleynik, D.; Panitkin, S.; Poyda, A.; Read, K. F.; Ryabinkin, E.; Teslyuk, A.; Velikhov, V.; Wells, J. C.; Wenaus, T.

2016-09-01

The Large Hadron Collider (LHC), operating at the international CERN Laboratory in Geneva, Switzerland, is leading Big Data driven scientific explorations. Experiments at the LHC explore the fundamental nature of matter and the basic forces that shape our universe, and were recently credited for the discovery of a Higgs boson. ATLAS, one of the largest collaborations ever assembled in the sciences, is at the forefront of research at the LHC. To address an unprecedented multi-petabyte data processing challenge, the ATLAS experiment is relying on a heterogeneous distributed computational infrastructure. The ATLAS experiment uses PanDA (Production and Data Analysis) Workload Management System for managing the workflow for all data processing on over 140 data centers. Through PanDA, ATLAS physicists see a single computing facility that enables rapid scientific breakthroughs for the experiment, even though the data centers are physically scattered all over the world. While PanDA currently uses more than 250000 cores with a peak performance of 0.3+ petaFLOPS, next LHC data taking runs will require more resources than Grid computing can possibly provide. To alleviate these challenges, LHC experiments are engaged in an ambitious program to expand the current computing model to include additional resources such as the opportunistic use of supercomputers. We will describe a project aimed at integration of PanDA WMS with supercomputers in United States, Europe and Russia (in particular with Titan supercomputer at Oak Ridge Leadership Computing Facility (OLCF), Supercomputer at the National Research Center "Kurchatov Institute", IT4 in Ostrava, and others). The current approach utilizes a modified PanDA pilot framework for job submission to the supercomputers batch queues and local data management, with light-weight MPI wrappers to run singlethreaded workloads in parallel on Titan's multi-core worker nodes. This implementation was tested with a variety of Monte-Carlo workloads

The future of PanDA in ATLAS distributed computing

Science.gov (United States)

De, K.; Klimentov, A.; Maeno, T.; Nilsson, P.; Oleynik, D.; Panitkin, S.; Petrosyan, A.; Schovancova, J.; Vaniachine, A.; Wenaus, T.

2015-12-01

Experiments at the Large Hadron Collider (LHC) face unprecedented computing challenges. Heterogeneous resources are distributed worldwide at hundreds of sites, thousands of physicists analyse the data remotely, the volume of processed data is beyond the exabyte scale, while data processing requires more than a few billion hours of computing usage per year. The PanDA (Production and Distributed Analysis) system was developed to meet the scale and complexity of LHC distributed computing for the ATLAS experiment. In the process, the old batch job paradigm of locally managed computing in HEP was discarded in favour of a far more automated, flexible and scalable model. The success of PanDA in ATLAS is leading to widespread adoption and testing by other experiments. PanDA is the first exascale workload management system in HEP, already operating at more than a million computing jobs per day, and processing over an exabyte of data in 2013. There are many new challenges that PanDA will face in the near future, in addition to new challenges of scale, heterogeneity and increasing user base. PanDA will need to handle rapidly changing computing infrastructure, will require factorization of code for easier deployment, will need to incorporate additional information sources including network metrics in decision making, be able to control network circuits, handle dynamically sized workload processing, provide improved visualization, and face many other challenges. In this talk we will focus on the new features, planned or recently implemented, that are relevant to the next decade of distributed computing workload management using PanDA.

The PANDA facility and first test results

International Nuclear Information System (INIS)

Dreier, J.; Huggenberger, M.; Aubert, C.; Bandurski, T.; Fischer, O.; Healzer, J.; Lomperski, S.; Strassberger, H.J.; Varadi, G.; Yadigaroglu, G.

1996-01-01

The PANDA test facility at the Paul Scherrer Institute is used to study the long-term performance of the Simplified Boiling Water Reactor's passive containment cooling system. The PANDA tests demonstrate performance on a larger scale than previous tests and examine the effects of any non-uniform spatial distributions of steam and non-condensable gases in the system. The facility is in 1:1 vertical scale and 1:25 scale for volume, power etc. Extensive facility characterization tests and steady-state passive containment condenser performance tests are presented. The results of the base case test of a series of transient system behaviour tests are reviewed. The first PANDA tests exhibited reproducibility, and indicated that the Simplified Boiling Water Reactor's containment is likely to be favorably responsive and highly robust to changes in the thermal transport patterns. (orig.) [de

The ATLAS PanDA Monitoring System and its Evolution

Science.gov (United States)

Klimentov, A.; Nevski, P.; Potekhin, M.; Wenaus, T.

2011-12-01

The PanDA (Production and Distributed Analysis) Workload Management System is used for ATLAS distributed production and analysis worldwide. The needs of ATLAS global computing imposed challenging requirements on the design of PanDA in areas such as scalability, robustness, automation, diagnostics, and usability for both production shifters and analysis users. Through a system-wide job database, the PanDA monitor provides a comprehensive and coherent view of the system and job execution, from high level summaries to detailed drill-down job diagnostics. It is (like the rest of PanDA) an Apache-based Python application backed by Oracle. The presentation layer is HTML code generated on the fly in the Python application which is also responsible for managing database queries. However, this approach is lacking in user interface flexibility, simplicity of communication with external systems, and ease of maintenance. A decision was therefore made to migrate the PanDA monitor server to Django Web Application Framework and apply JSON/AJAX technology in the browser front end. This allows us to greatly reduce the amount of application code, separate data preparation from presentation, leverage open source for tools such as authentication and authorization mechanisms, and provide a richer and more dynamic user experience. We describe our approach, design and initial experience with the migration process.

The ATLAS PanDA Monitoring System and its Evolution

International Nuclear Information System (INIS)

Klimentov, A; Nevski, P; Wenaus, T; Potekhin, M

2011-01-01

The PanDA (Production and Distributed Analysis) Workload Management System is used for ATLAS distributed production and analysis worldwide. The needs of ATLAS global computing imposed challenging requirements on the design of PanDA in areas such as scalability, robustness, automation, diagnostics, and usability for both production shifters and analysis users. Through a system-wide job database, the PanDA monitor provides a comprehensive and coherent view of the system and job execution, from high level summaries to detailed drill-down job diagnostics. It is (like the rest of PanDA) an Apache-based Python application backed by Oracle. The presentation layer is HTML code generated on the fly in the Python application which is also responsible for managing database queries. However, this approach is lacking in user interface flexibility, simplicity of communication with external systems, and ease of maintenance. A decision was therefore made to migrate the PanDA monitor server to Django Web Application Framework and apply JSON/AJAX technology in the browser front end. This allows us to greatly reduce the amount of application code, separate data preparation from presentation, leverage open source for tools such as authentication and authorization mechanisms, and provide a richer and more dynamic user experience. We describe our approach, design and initial experience with the migration process.

Functional annotation from the genome sequence of the giant panda.

Science.gov (United States)

Huo, Tong; Zhang, Yinjie; Lin, Jianping

2012-08-01

The giant panda is one of the most critically endangered species due to the fragmentation and loss of its habitat. Studying the functions of proteins in this animal, especially specific trait-related proteins, is therefore necessary to protect the species. In this work, the functions of these proteins were investigated using the genome sequence of the giant panda. Data on 21,001 proteins and their functions were stored in the Giant Panda Protein Database, in which the proteins were divided into two groups: 20,179 proteins whose functions can be predicted by GeneScan formed the known-function group, whereas 822 proteins whose functions cannot be predicted by GeneScan comprised the unknown-function group. For the known-function group, we further classified the proteins by molecular function, biological process, cellular component, and tissue specificity. For the unknown-function group, we developed a strategy in which the proteins were filtered by cross-Blast to identify panda-specific proteins under the assumption that proteins related to the panda-specific traits in the unknown-function group exist. After this filtering procedure, we identified 32 proteins (2 of which are membrane proteins) specific to the giant panda genome as compared against the dog and horse genomes. Based on their amino acid sequences, these 32 proteins were further analyzed by functional classification using SVM-Prot, motif prediction using MyHits, and interacting protein prediction using the Database of Interacting Proteins. Nineteen proteins were predicted to be zinc-binding proteins, thus affecting the activities of nucleic acids. The 32 panda-specific proteins will be further investigated by structural and functional analysis.

Functional annotation from the genome sequence of the giant panda

OpenAIRE

Huo, Tong; Zhang, Yinjie; Lin, Jianping

2012-01-01

The giant panda is one of the most critically endangered species due to the fragmentation and loss of its habitat. Studying the functions of proteins in this animal, especially specific trait-related proteins, is therefore necessary to protect the species. In this work, the functions of these proteins were investigated using the genome sequence of the giant panda. Data on 21,001 proteins and their functions were stored in the Giant Panda Protein Database, in which the proteins were divided in...

Evolution of the ATLAS PanDA workload management system for exascale computational science

International Nuclear Information System (INIS)

Maeno, T; Klimentov, A; Panitkin, S; Schovancova, J; Wenaus, T; Yu, D; De, K; Nilsson, P; Oleynik, D; Petrosyan, A; Vaniachine, A

2014-01-01

An important foundation underlying the impressive success of data processing and analysis in the ATLAS experiment [1] at the LHC [2] is the Production and Distributed Analysis (PanDA) workload management system [3]. PanDA was designed specifically for ATLAS and proved to be highly successful in meeting all the distributed computing needs of the experiment. However, the core design of PanDA is not experiment specific. The PanDA workload management system is capable of meeting the needs of other data intensive scientific applications. Alpha-Magnetic Spectrometer [4], an astro-particle experiment on the International Space Station, and the Compact Muon Solenoid [5], an LHC experiment, have successfully evaluated PanDA and are pursuing its adoption. In this paper, a description of the new program of work to develop a generic version of PanDA will be given, as well as the progress in extending PanDA's capabilities to support supercomputers and clouds and to leverage intelligent networking. PanDA has demonstrated at a very large scale the value of automated dynamic brokering of diverse workloads across distributed computing resources. The next generation of PanDA will allow other data-intensive sciences and a wider exascale community employing a variety of computing platforms to benefit from ATLAS' experience and proven tools.

PanDA: distributed production and distributed analysis system for ATLAS

International Nuclear Information System (INIS)

Maeno, T

2008-01-01

A new distributed software system was developed in the fall of 2005 for the ATLAS experiment at the LHC. This system, called PANDA, provides an integrated service architecture with late binding of jobs, maximal automation through layered services, tight binding with ATLAS Distributed Data Management system [1], advanced error discovery and recovery procedures, and other features. In this talk, we will describe the PANDA software system. Special emphasis will be placed on the evolution of PANDA based on one and half year of real experience in carrying out Computer System Commissioning data production [2] for ATLAS. The architecture of PANDA is well suited for the computing needs of the ATLAS experiment, which is expected to be one of the first HEP experiments to operate at the petabyte scale

Estrés Laboral en Médicos Residentes del Hospital Nacional Carlos Alberto Seguín Escobedo y del Hospital Regional Honorio Delgado Espinosa. Arequipa, 2015

OpenAIRE

Mazeyra Guillén, Alvaro Augusto

2017-01-01

El presente estudio tuvo como objetivos determinar el estrés laboral en los médicos residentes del Hospital “Carlos Alberto Seguín Escobedo” de EsSalud (HNCASE). y del Hospital Regional “Honorio Delgado Espinosa” (HRHDE) y establecer las semejanzas y diferencias del estrés laboral de los médicos residentes de ambos hospitales. La población estuvo conformada por 220 médicos residentes de primero, segundo y tercer año de residencia. Se aplicó el muestreo al azar estratifica...

The ATLAS PanDA Monitoring System and its Evolution

CERN Document Server

Klimentov, A; The ATLAS collaboration; Potekhin, M; Wenaus, T

2011-01-01

The PanDA (Production and Distributed Analysis) Workload Management System is used for ATLAS distributed production and analysis worldwide. The needs of ATLAS global computing imposed challenging requirements on PanDA design in areas such as scalability, robustness, automation, diagnostics, and usability for both production shifters and analysis users. Important to meeting these and other requirements is a comprehensive monitoring system. Through a system-wide job database, the PanDA monitor provides a comprehensive and coherent view of the system and job execution, from high level summaries to detailed drill-down job diagnostics. It is (like the rest of PanDA) an Apache-based Python application backed by Oracle. The presentation layer is HTML code generated on the fly in the Python application which is also responsible for managing database queries. However, this approach is lacking in user interface flexibility, simplicity of communication with external systems, and ease of maintenance. We decided to migrat...

The ATLAS PanDA Monitoring System and its Evolution

CERN Document Server

Klimentov, A; The ATLAS collaboration; Potekhin, M; Wenaus, T

2010-01-01

The PanDA (Production and Distributed Analysis) Workload Management System is used for ATLAS distributed production and analysis worldwide. The needs of ATLAS global computing imposed challenging requirements on PanDA design in areas such as scalability, robustness, automation, diagnostics, and usability for both production shifters and analysis users. Important to meeting these and other requirements is a comprehensive monitoring system. Through a system-wide job database, the PanDA monitor provides a comprehensive and coherent view of the system and job execution, from high level summaries to detailed drill-down job diagnostics. It is (like the rest of PanDA) an Apache-based Python application backed by Oracle. The presentation layer is HTML code generated on the fly in the Python application which is also responsible for managing database queries. However, this approach is lacking in user interface flexibility, simplicity of communication with external systems, and ease of maintenance. We decided to migrat...

GPU implementations of online track finding algorithms at PANDA

Energy Technology Data Exchange (ETDEWEB)

Herten, Andreas; Stockmanns, Tobias; Ritman, James [Institut fuer Kernphysik, Forschungszentrum Juelich GmbH (Germany); Adinetz, Andrew; Pleiter, Dirk [Juelich Supercomputing Centre, Forschungszentrum Juelich GmbH (Germany); Kraus, Jiri [NVIDIA GmbH (Germany); Collaboration: PANDA-Collaboration

2014-07-01

The PANDA experiment is a hadron physics experiment that will investigate antiproton annihilation in the charm quark mass region. The experiment is now being constructed as one of the main parts of the FAIR facility. At an event rate of 2 . 10{sup 7}/s a data rate of 200 GB/s is expected. A reduction of three orders of magnitude is required in order to save the data for further offline analysis. Since signal and background processes at PANDA have similar signatures, no hardware-level trigger is foreseen for the experiment. Instead, a fast online event filter is substituting this element. We investigate the possibility of using graphics processing units (GPUs) for the online tracking part of this task. Researched algorithms are a Hough Transform, a track finder involving Riemann surfaces, and the novel, PANDA-specific Triplet Finder. This talk shows selected advances in the implementations as well as performance evaluations of the GPU tracking algorithms to be used at the PANDA experiment.

The Future of PanDA in ATLAS Distributed Computing

CERN Document Server

De, Kaushik; The ATLAS collaboration; Maeno, Tadashi; Nilsson, Paul; Oleynik, Danila; Panitkin, Sergey; Petrosyan, Artem; Schovancova, Jaroslava; Vaniachine, Alexandre; Wenaus, Torre

2015-01-01

Experiments at the Large Hadron Collider (LHC) face unprecedented computing challenges. Heterogeneous resources are distributed worldwide at hundreds of sites, thousands of physicists analyze the data remotely, the volume of processed data is beyond the exabyte scale, while data processing requires more than a few billion hours of computing usage per year. The PanDA (Production and Distributed Analysis) system was developed to meet the scale and complexity of LHC distributed computing for the ATLAS experiment. In the process, the old batch job paradigm of locally managed computing in HEP was discarded in favor of a far more automated, flexible and scalable model. The success of PanDA in ATLAS is leading to widespread adoption and testing by other experiments. PanDA is the first exascale workload management system in HEP, already operating at more than a million computing jobs per day, and processing over an exabyte of data in 2013. There are many new challenges that PanDA will face in the near future, in addi...

LWR containment safety research in PANDA

International Nuclear Information System (INIS)

Paladino, D.; Huggenberger, M.; Andreani, M.; Gupta, S.; Guentay, S.; Dreier, J.; Prasser, H.

2008-01-01

In the frame of the OECD/SETH-2 project, an experimental program is being carried out at PSI (PANDA Facility in Switzerland) and CEA (MISTRA Facility in France) with the aim of generating high-quality experimental data which will be used for improving modeling and for Lumped Parameter and 3D (CFD) code validations. The PANDA test program consists of seven types of test series, focusing on gas stratification break-up induced b) mass sources (simulating the release of steam and hydrogen), heat sources (simulating the energy) generated hydrogen-oxygen recombiner operation) or heat sinks (due to condensation of steam caused by containment coolers, sprays or 'cold' walls). Two series of PANDA tests are devoted to obtaining detailed data on the integral behavior of Passive Containment Cooling Systems (PCCS) of Advanced Light Water Reactors (ALWR) in the presence of different non-condensable gases (air; hydrogen) and also to investigating the gas mixing and stratification induced by the sudden interconnection of compartments with large gas concentration differences, e.g. the opening of rupture disks. (authors)

PD2P : PanDA Dynamic Data Placement for ATLAS

OpenAIRE

Maeno, T; De, K; Panitkin, S

2012-01-01

The PanDA (Production and Distributed Analysis) system plays a key role in the ATLAS distributed computing infrastructure. PanDA is the ATLAS workload management system for processing all Monte-Carlo (MC) simulation and data reprocessing jobs in addition to user and group analysis jobs. The PanDA Dynamic Data Placement (PD2P) system has been developed to cope with difficulties of data placement for ATLAS. We will describe the design of the new system, its performance during the past year of d...

Optimizing new components of PanDA for ATLAS production on HPC resources

CERN Document Server

Maeno, Tadashi; The ATLAS collaboration

2017-01-01

The Production and Distributed Analysis system (PanDA) has been used for workload management in the ATLAS Experiment for over a decade. It uses pilots to retrieve jobs from the PanDA server and execute them on worker nodes. While PanDA has been mostly used on Worldwide LHC Computing Grid (WLCG) resources for production operations, R&D work has been ongoing on cloud and HPC resources for many years. These efforts have led to the significant usage of large scale HPC resources in the past couple of years. In this talk we will describe the changes to the pilot which enabled the use of HPC sites by PanDA, specifically the Titan supercomputer at Oakridge National Laboratory. Furthermore, it was decided in 2016 to start a fresh redesign of the Pilot with a more modern approach to better serve present and future needs from ATLAS and other collaborations that are interested in using the PanDA System. Another new project for development of a resource oriented service, PanDA Harvester, was also launched in 2016. The...

Usability and feasibility of a mobile health system to provide comprehensive antenatal care in low-income countries: PANDA mHealth pilot study in Madagascar.

Science.gov (United States)

Benski, Anne Caroline; Stancanelli, Giovanna; Scaringella, Stefano; Herinainasolo, Josea Léa; Jinoro, Jéromine; Vassilakos, Pierre; Petignat, Patrick; Schmidt, Nicole C

2017-06-01

Background Madagascar's maternal health mortality ratio in 2013 was 478 deaths per 100,000 live births. Most deaths are related to direct complications during pregnancy and childbirth and could be reduced by providing comprehensive antenatal care (ANC). Objective The objective of the study was to assess the usability and feasibility of a mobile health system (mHealth) to provide high-quality ANC, according to World Health Organization (WHO) recommendations. Methods PANDA (Pregnancy And Newborn Diagnostic Assessment) is an easy-to-use mHealth system that uses affordable communications technology to support diagnosis and health care worker decision-making regarding ANC. From January to March 2015, a cross-sectional pilot study was conducted in Ambanja District, Madagascar, in which ANC using PANDA was provided to 100 pregnant women. The collected data were transmitted to a database in the referral hospital to create individual electronic patient records. Accuracy and completeness of the data were closely controlled. The PANDA software was assessed and the number of abnormal results, treatments performed, and participants requiring referral to health care facilities were monitored. Results The PANDA system facilitated creation of individual electronic patient records that included socio-demographic and medical data for 100 participants. Duration of ANC visits averaged 29.6 min. Health care providers were able to collect all variables (100%) describing personal and medical data. No major technical problems were encountered and no data were lost. During 17 ANC visits (17%), an alert function was generated to highlight abnormal clinical results requiring therapy or referral to an affiliated hospital. Participants' acceptability of the system was very high. Conclusion This pilot study proved the usability and feasibility of the PANDA mHealth system to conduct complete and standardised ANC visits according to WHO guidelines, thus providing a promising solution to

Long noncoding RNA PANDA and scaffold-attachment-factor SAFA control senescence entry and exit.

Science.gov (United States)

Puvvula, Pavan Kumar; Desetty, Rohini Devi; Pineau, Pascal; Marchio, Agnés; Moon, Anne; Dejean, Anne; Bischof, Oliver

2014-11-19

Cellular senescence is a stable cell cycle arrest that limits the proliferation of pre-cancerous cells. Here we demonstrate that scaffold-attachment-factor A (SAFA) and the long noncoding RNA PANDA differentially interact with polycomb repressive complexes (PRC1 and PRC2) and the transcription factor NF-YA to either promote or suppress senescence. In proliferating cells, SAFA and PANDA recruit PRC complexes to repress the transcription of senescence-promoting genes. Conversely, the loss of SAFA-PANDA-PRC interactions allows expression of the senescence programme. Accordingly, we find that depleting either SAFA or PANDA in proliferating cells induces senescence. However, in senescent cells where PANDA sequesters transcription factor NF-YA and limits the expression of NF-YA-E2F-coregulated proliferation-promoting genes, PANDA depletion leads to an exit from senescence. Together, our results demonstrate that PANDA confines cells to their existing proliferative state and that modulating its level of expression can cause entry or exit from senescence.

The ψ(4040) at the future PANDA experiment

International Nuclear Information System (INIS)

Zotti, L; Marcello, S; Spataro, S; Filippi, A

2014-01-01

The PANDA experiment will be carried out at the future FAIR facility, it will be a fixed target experiment, where antiproton beams, of unprecedented quality and intensity, will be used to study interactions on protons and on nuclei. PANDA will be an excellent tool to investigate those final states which include short-lived particles. Since different charmonium states can be accessed in direct formation with all the available quantum numbers in p-bar p annihilations, the charmonium spectroscopy is one of the main goal of the experiment. The PANDA experiment represents a unique possibility to improve both statistics and precision of existing data and to further explore the physics in the charm quark sector. Indeed, an energy scan with high precision over the full charm spectrum is still missing and it will not be delivered by future experiments currently planned as upgrade of the existing facilities. A detailed description of the possibility to reconstruct the ψ(4040) → D *+ D *− at PANDA, together with the study of the huge hadronic background suppression will be presented. The importance of the Micro-Vertex Detector for the reconstruction of D mesons decay will be showed.

Tracking with Straw Tubes in the PANDA Experiment

Directory of Open Access Journals (Sweden)

Bragadireanu M.

2014-03-01

Full Text Available The PANDA spectrometer will be built at the FAIR facility at Darmstadt (Germany to perform accurate tests of the strong interaction through ¯pp and ¯pA annihilation studies. The charged particle tracking at PANDA will be done using both solid state and gaseous detectors. Among the latter, two straw tube detector systems will be built [1]. The cylindrical, central straw tube tracker features a high spatial and momentum resolution for a wide range of particle momenta from about 8 GeV/c down to a few 100 MeV/c, together with particle identification in the momentum region below about 1 GeV/c by measuring the specific energy-loss. A new technique, based on self-supporting straw double layers with intrinsic wire tension developed for the COSY-TOF straw tracker [2], has been adopted for the PANDA trackers. The development of the readout electronics for the straw tubes is ongoing. Prototypes have been produced and used to instrument straw tube modules that have been tested with cosmic rays and proton beams. Design issues of the PANDA straw tubes, together with the results of the prototype tests are presented.

Online and Offline Pattern Recognition in PANDA

Directory of Open Access Journals (Sweden)

Boca Gianluigi

2016-01-01

Full Text Available PANDA is one of the four experiments that will run at the new facility FAIR that is being built in Darmstadt, Germany. It is a fixed target experiment: a beam of antiprotons collides on a jet proton target (the maximum center of mass energy is 5.46 GeV. The interaction rate at the startup will be 2MHz with the goal of reaching 20MHz at full luminosity. The beam of antiprotons will be essentially continuous. PANDA will have NO hardware trigger but only a software trigger, to allow for maximum flexibility in the physics program. All those characteristics are severe challenges for the reconstruction code that 1 must be fast, since it has to be validated up to 20MHz interaction rate; 2 must be able to reject fake tracks caused by the remnant hits, belonging to previous or later events in some slow detectors, for example the straw tubes in the central region. The Pattern Recognition (PR of PANDA will have to run both online to achieve a first fast selection, and offline, at lower rate, for a more refined selection. In PANDA the PR code is continuously evolving; this contribution shows the present status. I will give an overview of three examples of PR following different strategies and/or implemented on different hardware (FPGA, GPUs, CPUs and, when available, I will report the performances.

Online and Offline Pattern Recognition in PANDA

Science.gov (United States)

Boca, Gianluigi

2016-11-01

PANDA is one of the four experiments that will run at the new facility FAIR that is being built in Darmstadt, Germany. It is a fixed target experiment: a beam of antiprotons collides on a jet proton target (the maximum center of mass energy is 5.46 GeV). The interaction rate at the startup will be 2MHz with the goal of reaching 20MHz at full luminosity. The beam of antiprotons will be essentially continuous. PANDA will have NO hardware trigger but only a software trigger, to allow for maximum flexibility in the physics program. All those characteristics are severe challenges for the reconstruction code that 1) must be fast, since it has to be validated up to 20MHz interaction rate; 2) must be able to reject fake tracks caused by the remnant hits, belonging to previous or later events in some slow detectors, for example the straw tubes in the central region. The Pattern Recognition (PR) of PANDA will have to run both online to achieve a first fast selection, and offline, at lower rate, for a more refined selection. In PANDA the PR code is continuously evolving; this contribution shows the present status. I will give an overview of three examples of PR following different strategies and/or implemented on different hardware (FPGA, GPUs, CPUs) and, when available, I will report the performances.

Habitat Use and Selection by Giant Pandas

Science.gov (United States)

Hull, Vanessa; Zhang, Jindong; Huang, Jinyan; Zhou, Shiqiang; Viña, Andrés; Shortridge, Ashton; Li, Rengui; Liu, Dian; Xu, Weihua; Ouyang, Zhiyun; Zhang, Hemin; Liu, Jianguo

2016-01-01

Animals make choices about where to spend their time in complex and dynamic landscapes, choices that reveal information about their biology that in turn can be used to guide their conservation. Using GPS collars, we conducted a novel individual-based analysis of habitat use and selection by the elusive and endangered giant pandas (Ailuropoda melanoleuca). We constructed spatial autoregressive resource utilization functions (RUF) to model the relationship between the pandas' utilization distributions and various habitat characteristics over a continuous space across seasons. Results reveal several new insights, including use of a broader range of habitat characteristics than previously understood for the species, particularly steep slopes and non-forest areas. We also used compositional analysis to analyze habitat selection (use with respect to availability of habitat types) at two selection levels. Pandas selected against low terrain position and against the highest clumped forest at the at-home range level, but no significant factors were identified at the within-home range level. Our results have implications for modeling and managing the habitat of this endangered species by illustrating how individual pandas relate to habitat and make choices that differ from assumptions made in broad scale models. Our study also highlights the value of using a spatial autoregressive RUF approach on animal species for which a complete picture of individual-level habitat use and selection across space is otherwise lacking. PMID:27627805

Habitat Use and Selection by Giant Pandas.

Directory of Open Access Journals (Sweden)

Vanessa Hull

Full Text Available Animals make choices about where to spend their time in complex and dynamic landscapes, choices that reveal information about their biology that in turn can be used to guide their conservation. Using GPS collars, we conducted a novel individual-based analysis of habitat use and selection by the elusive and endangered giant pandas (Ailuropoda melanoleuca. We constructed spatial autoregressive resource utilization functions (RUF to model the relationship between the pandas' utilization distributions and various habitat characteristics over a continuous space across seasons. Results reveal several new insights, including use of a broader range of habitat characteristics than previously understood for the species, particularly steep slopes and non-forest areas. We also used compositional analysis to analyze habitat selection (use with respect to availability of habitat types at two selection levels. Pandas selected against low terrain position and against the highest clumped forest at the at-home range level, but no significant factors were identified at the within-home range level. Our results have implications for modeling and managing the habitat of this endangered species by illustrating how individual pandas relate to habitat and make choices that differ from assumptions made in broad scale models. Our study also highlights the value of using a spatial autoregressive RUF approach on animal species for which a complete picture of individual-level habitat use and selection across space is otherwise lacking.

Enfermos del Hospital General de Mallorca a fines del siglo XV

OpenAIRE

Contreras Mas, Antonio

2012-01-01

Introducción: Presentamos un estudio sobre los hombres y mujeres que fueron internados en el Hospital General de Mallorca en los últimos años del siglo XV. Se basa en los listados donde se recogieron los detalles personales de algunos de los sujetos allí acogidos entre los años 1482 y 1494. Tras revisar las causas principales de la fundación del establecimiento y algunas noticias sobre este proceso, se examinan determinadas características de los hombres y mujeres a los que prestó asistencia ...

Mesons, PANDA and the scalar glueball

International Nuclear Information System (INIS)

Parganlija, Denis

2014-01-01

The non-perturbative nature of Quantum Chromodynamics (QCD) at low energies has prompted the expectation that the gauge-bosons of QCD – gluons – might give rise to compound objects denoted as glueballs. Experimental signals for glueballs have represented a matter of research for various collaborations in the last decades; future research in this direction is a main endeavour planned by the PANDA Collaboration at FAIR. Hence in this article I review some of the outstanding issues in the glueball search, particularly with regard to the ground state – the scalar glueball, and discuss the relevance for PANDA at FAIR.

Evolution of the ATLAS PanDA Workload Management System for Exascale Computational Science

OpenAIRE

Maeno, T; De, K; Klimentov, A; Nilsson, P; Oleynik, D; Panitkin, S; Petrosyan, A; Schovancova, J; Vaniachine, A; Wenaus, T; Yu, D

2013-01-01

An important foundation underlying the impressive success of data processing and analysis in the ATLAS experiment [1] at the LHC [2] is the Production and Distributed Analysis (PanDA) workload management system [3]. PanDA was designed specifically for ATLAS and proved to be highly successful in meeting all the distributed computing needs of the experiment. However, the core design of PanDA is not experiment specific. The PanDA workload management system is capable of meeting the needs of othe...

B N Panda

Indian Academy of Sciences (India)

Home; Journals; Pramana – Journal of Physics. B N Panda. Articles written in Pramana – Journal of Physics. Volume 77 Issue 4 October 2011 pp 715-726 Research Articles. Effect of hybridization and dispersion of quasiparticles on the coexistent state of superconductivity and antiferromagnetism in Ni2B2C · B K Sahoo ...

Fatal Toxoplasma gondii infection in the giant panda

Directory of Open Access Journals (Sweden)

2015-01-01

Full Text Available Toxoplasma gondii can infect nearly all warm-blooded animals. We report an acute fatal T. gondii infection in the endangered giant panda (Ailuropoda melanoleuca in a zoo in China, characterized by acute gastroenteritis and respiratory symptoms. T. gondii infection was confirmed by immunological and molecular methods. Multilocus nested PCR-RFLP revealed clonal type I at the SAG1 and c29-2 loci, clonal type II at the SAG2, BTUB, GRA6, c22-8, and L358 loci, and clonal type III at the alternative SAG2 and SAG3 loci, thus, a potential new genotype of T. gondii in the giant panda. Other possible pathogens were not detected. To our knowledge, this is the first report of clinical toxoplasmosis in a giant panda.

Formation of double-{Lambda} hypernuclei at PANDA

Energy Technology Data Exchange (ETDEWEB)

Gaitanos, T., E-mail: Theodoros.Gaitanos@theo.physik.uni-giessen.de [Institut fuer Theoretische Physik, Universitaet Giessen, D-35392, Giessen (Germany); Larionov, A.B.; Lenske, H.; Mosel, U. [Institut fuer Theoretische Physik, Universitaet Giessen, D-35392, Giessen (Germany)

2012-05-01

We study the formation of single- and double-{Lambda} hypernuclei in antiproton-induced reactions relevant for the forthcoming PANDA experiment at FAIR. We use the Giessen Boltzmann-Uehling-Uhlenbeck (GiBUU) transport model with relativistic mean-fields for the description of non-equilibrium dynamics and the statistical multifragmentation model (SMM) for fragment formation. This combined approach describes the dynamical properties of strangeness and fragments in low energy p{sup Macron}-induced reactions fairly well. We then focus on the formation of double-{Lambda} hypernuclei in high energy p{sup Macron}-nucleus collisions on a primary target including the complementary {Xi}-induced reactions to a secondary one, as proposed by the PANDA Collaboration. Our results show that a copious production of double-{Lambda} hyperfragments is possible at PANDA. In particular, we provide first theoretical estimations on the double-{Lambda} production cross section, which strongly rises with decreasing energy of the secondary {Xi}-beam.

The ATLAS PanDA Pilot in Operation

International Nuclear Information System (INIS)

Nilsson, P; De, K; Stradling, A; Caballero, J; Maeno, T; Wenaus, T

2011-01-01

The Production and Distributed Analysis system (PanDA) was designed to meet ATLAS requirements for a data-driven workload management system capable of operating at LHC data processing scale. Submitted jobs are executed on worker nodes by pilot jobs sent to the grid sites by pilot factories. This paper provides an overview of the PanDA pilot system and presents major features added in light of recent operational experience, including multi-job processing, advanced job recovery for jobs with output storage failures, gLExec based identity switching from the generic pilot to the actual user, and other security measures. The PanDA system serves all ATLAS distributed processing and is the primary system for distributed analysis; it is currently used at over 100 sites worldwide. We analyze the performance of the pilot system in processing real LHC data on the OSG, EGI and Nordugrid infrastructures used by ATLAS, and describe plans for its evolution.

RADIOGRAPHIC THORACIC ANATOMY OF THE RED PANDA (AILURUS FULGENS).

Science.gov (United States)

Makungu, Modesta; du Plessis, Wencke M; Barrows, Michelle; Groenewald, Hermanus B; Koeppel, Katja N

2016-09-01

The red panda ( Ailurus fulgens ) is classified as an endangered species by the International Union for Conservation of Nature and Natural Resources. The natural distribution of the red panda is in the Himalayas and southern China. Thoracic diseases such as dirofilariasis, hypertrophic cardiomyopathy, tracheal obstruction, lung worm infestation, and pneumonia have been reported in the red panda. The aim of this study was to describe the normal radiographic thoracic anatomy of captive red pandas as a species-specific reference for routine health examinations and clinical cases. Right lateral (RL) and dorsoventral (DV) inspiratory phase views of the thorax were obtained in 11 adult captive red pandas. Measurements were made and ratios calculated to establish reference ranges for the mean vertebral heart score on the RL (8.34 ± 0.25) and DV (8.78 ± 0.34) views and the mean ratios of the caudal vena cava diameter to the vertebral body length above tracheal bifurcation (0.67 ± 0.05) and tracheal diameter to the width of the third rib (2.75 ± 0.24). The majority of animals (10/11) had 14 thoracic vertebrae, except for one animal that had 15 thoracic vertebrae. Rudimentary clavicles were seen in 3/11 animals. The ovoid, oblique cardiac silhouette was more horizontally positioned and elongated in older animals. A redundant aortic arch was seen in the oldest animal. The trachea was seen with mineralized cartilage rings in all animals. The carina was clearly seen in the majority of animals (10/11). Variations exist in the normal radiographic thoracic anatomy of different species. Knowledge of the normal radiographic thoracic anatomy of the red panda should prove useful for routine health examinations and in the diagnosis of thoracic diseases.

The PANDA experiment at FAIR

International Nuclear Information System (INIS)

Bussa, M.P.

2005-01-01

The approved FAIR upgrade of the GSI facility in Darmstadt, Germany, includes the construction of a High Energy Storage Ring (HESR) for high intensity, phase space cooled antiprotons with momenta up to 15 GeV/c. A wide physics program is planned at this facility to investigate fundamental questions of hadron and nuclear physics in interactions of antiprotons with nucleons and nuclei. To serve the many experiments planned at this new facility, an universal, modular, hermetic spectrometer called PANDA (Proton ANtiproton Detector Array) is planned. This talk presents an overview of the physics program pursued by this project and of the PANDA detector system. The feasibility of measurements in the sector of spin degrees of freedom of quarks will be also discussed. (author)

Giant panda foraging and movement patterns in response to bamboo shoot growth.

Science.gov (United States)

Zhang, Mingchun; Zhang, Zhizhong; Li, Zhong; Hong, Mingsheng; Zhou, Xiaoping; Zhou, Shiqiang; Zhang, Jindong; Hull, Vanessa; Huang, Jinyan; Zhang, Hemin

2018-03-01

Diet plays a pivotal role in dictating behavioral patterns of herbivorous animals, particularly specialist species. The giant panda (Ailuropoda melanoleuca) is well-known as a bamboo specialist. In the present study, the response of giant pandas to spatiotemporal variation of bamboo shoots was explored using field surveys and GPS collar tracking. Results show the dynamics in panda-bamboo space-time relationships that have not been previously articulated. For instance, we found a higher bamboo stump height of foraged bamboo with increasing elevation, places where pandas foraged later in spring when bamboo shoots become more fibrous and woody. The time required for shoots to reach optimum height for foraging was significantly delayed as elevation increased, a pattern which corresponded with panda elevational migration patterns beginning from the lower elevational end of Fargesia robusta distribution and gradually shifting upward until the end of the shooting season. These results indicate that giant pandas can respond to spatiotemporal variation of bamboo resources, such as available shoots. Anthropogenic interference of low-elevation F. robusta habitat should be mitigated, and conservation attention and increased monitoring should be given to F. robusta areas at the low- and mid-elevation ranges, particularly in the spring shooting season.

Canine distemper viral infection threatens the giant panda population in China

Science.gov (United States)

Jin, Yipeng; Zhang, Xinke; Ma, Yisheng; Qiao, Yanchao; Liu, Xiaobin; Zhao, Kaihui; Zhang, Chenglin; Lin, Degui; Fu, Xuelian; Xu, Xinrong; Wang, Yiwei; Wang, Huanan

2017-01-01

We evaluated exposure to canine distemper virus (CDV) in eight wild giant pandas (Ailuropoda melanoleuca) and 125 unvaccinated domestic dogs living in and around Foping National Nature Reserve (FNNR), China. Seventy-two percent of unvaccinated domestic dogs (mixed breed) had neutralizing antibodies for CDV due to exposure to the disease. The eight wild giant pandas were naïve to CDV and carried no positive antibody titer. RT-PCR assays for hemagglutinin (H) gene confirmed the presence of CDV in 31 clinically ill dogs from several areas near FNNR. Genomic sequence analysis showed that the 21 canine CDV were highly homologous to each other and belonged to the Asian-1 genotype. They showed high homology with the GP01 strain sequenced from a fatally infected giant panda, suggesting cross-species infection. Observational and GPS tracking data revealed home range overlap in pandas and dogs around FNNR. This study shows that CDV is endemic in domestic dogs near FNNR and that cross-species CDV infection threatens the wild giant panda population. PMID:29371956

Canine distemper viral infection threatens the giant panda population in China.

Science.gov (United States)

Jin, Yipeng; Zhang, Xinke; Ma, Yisheng; Qiao, Yanchao; Liu, Xiaobin; Zhao, Kaihui; Zhang, Chenglin; Lin, Degui; Fu, Xuelian; Xu, Xinrong; Wang, Yiwei; Wang, Huanan

2017-12-26

We evaluated exposure to canine distemper virus (CDV) in eight wild giant pandas ( Ailuropoda melanoleuca ) and 125 unvaccinated domestic dogs living in and around Foping National Nature Reserve (FNNR), China. Seventy-two percent of unvaccinated domestic dogs (mixed breed) had neutralizing antibodies for CDV due to exposure to the disease. The eight wild giant pandas were naïve to CDV and carried no positive antibody titer. RT-PCR assays for hemagglutinin ( H ) gene confirmed the presence of CDV in 31 clinically ill dogs from several areas near FNNR. Genomic sequence analysis showed that the 21 canine CDV were highly homologous to each other and belonged to the Asian-1 genotype. They showed high homology with the GP01 strain sequenced from a fatally infected giant panda, suggesting cross-species infection. Observational and GPS tracking data revealed home range overlap in pandas and dogs around FNNR. This study shows that CDV is endemic in domestic dogs near FNNR and that cross-species CDV infection threatens the wild giant panda population.

Permanent Advisory Network for Diseases in Aquaculture (PANDA)

OpenAIRE

Arzul, Isabelle; Ariel, E.; Hill, B.

2005-01-01

The PANDA project aims to establish a permanent network of aquatic animal health specialists (researchers and diagnosticians) to provide a forum for the debate of issues concerning diseases in European aquaculture, and to communicate the results of these discussions to the European Commission with provision of advice on EU policy and legislation for aquatic animal health. PANDA consists of five scientific work packages: risk analysis, epidemiology, diagnosis, environmentally safe strategies f...

Changes of foraging patch selection and utilization by a giant panda after bamboo flowering.

Science.gov (United States)

Li, Guochun; Song, Huadong; Altigani, Latifa A A; Zheng, Xueli; Bu, Shuhai

2017-07-01

The bamboo flowering leads to the habitat fragmentation and food quality decline of a giant panda. Few empirical research has been conducted about the giant panda's response to the bamboo flowering. Here, we investigated the characteristics of bamboo stands, giant panda's activity, and selection and utilization of bamboo stands by giant panda in Taibaishan National Nature Reserve, China, over a 3-year period (September 2013-May 2016) during the Fargesia qinlingensis flowering period. Our results indicated that the proportion of whole bamboo stands flowering has gradually expanded from 26.7% in 2013 and 33.9% in 2014 to 52.3% in 2015. Although the flowering bamboo has lower crude protein and higher crude fiber than a non-flowering bamboo, the giant panda still fed on flowering bamboo from the evidence of droppings. The giant panda left its feeding sites and moved to the high elevation along river when the proportion of flowering reached 69.2% at elevation of 2350-2450 m in the third year. With the decline of the quality of bamboo stand of Fargesia qinlingensis, the giant panda abandoned its feeding sites when the threshold value of bamboo flowering reached 56.9-69.2%. Flexibility in foraging strategy and spatial behavior can help the giant panda to better adapt to the environment.

MOLECULAR CLONING, SEQUENCING, EXPRESSION AND BIOLOGICAL ACTIVITY OF GIANT PANDA (AILUROPODA MELANOLEUCA) INTERFERON-GAMMA.

Science.gov (United States)

Zhu, Hui; Wang, Wen-Xiu; Wang, Bao-Qin; Zhu, Xiao-Fu; Wu, Xu-Jin; Ma, Qing-Yi; Chen, De-Kun

2012-06-29

The giant panda (Ailuropoda melanoleuca) is an endangered species and indigenous to China. Interferon-gamma (IFN-γ) is the only member of type □ IFN and is vital for the regulation of host adapted immunity and inflammatory response. Little is known aboutthe FN-γ gene and its roles in giant panda.In this study, IFN-γ gene of Qinling giant panda was amplified from total blood RNA by RT-CPR, cloned, sequenced and analysed. The open reading frame (ORF) of Qinling giant panda IFN-γ encodes 152 amino acidsand is highly similar to Sichuan giant panda with an identity of 99.3% in cDNA sequence. The IFN-γ cDNA sequence was ligated to the pET32a vector and transformed into E. coli BL21 competent cells. Expression of recombinant IFN-γ protein of Qinling giant panda in E. coli was confirmed by SDS-PAGE and Western blot analysis. Biological activity assay indicated that the recombinant IFN-γ protein at the concentration of 4-10 µg/ml activated the giant panda peripheral blood lymphocytes,while at 12 µg/mlinhibited. the activation of the lymphocytes.These findings provide insights into the evolution of giant panda IFN-γ and information regarding amino acid residues essential for their biological activity.

Dietary resources shape the adaptive changes of cyanide detoxification function in giant panda (Ailuropoda melanoleuca).

Science.gov (United States)

Huang, He; Yie, Shangmian; Liu, Yuliang; Wang, Chengdong; Cai, Zhigang; Zhang, Wenping; Lan, Jingchao; Huang, Xiangming; Luo, Li; Cai, Kailai; Hou, Rong; Zhang, Zhihe

2016-10-05

The functional adaptive changes in cyanide detoxification in giant panda appear to be response to dietary transition from typical carnivore to herbivorous bear. We tested the absorption of cyanide contained in bamboo/bamboo shoots with a feeding trial in 20 adult giant pandas. We determined total cyanide content in bamboo shoots and giant panda's feces, levels of urinary thiocyanate and tissue rhodanese activity using color reactions with a spectrophotometer. Rhodanese expression in liver and kidney at transcription and translation levels were measured using real-time RT-PCR and immunohistochemistry, respectively. We compared differences of rhodanese activity and gene expressions among giant panda, rabbit (herbivore) and cat (carnivore), and between newborn and adult giant pandas. Bamboo shoots contained 3.2 mg/kg of cyanide and giant pandas absorbed more than 65% of cyanide. However, approximately 80% of absorbed cyanide was metabolized to less toxic thiocyanate that was discharged in urine. Rhodanese expression and activity in liver and kidney of giant panda were significantly higher than in cat, but lower than in rabbit (all P pandas were higher than that in newborn cub. Phylogenetic analysis of both nucleotide and amino acid sequences of the rhodanese gene supported a closer relationship of giant panda with carnivores than with herbivores.

Gastric dilitation-volvulus in a Red Panda (Ailurus fulgens).

Science.gov (United States)

Schlanser, Justin R; Agnew, Dalen; Paperd, Deborah W; Harrison, Tara M

2014-06-01

A 10-year-old male red panda presented acutely with symptoms of shock due to acute abdominal distress and respiratory compromise. Abdominal ultrasound confirmed a severely distended stomach for which passage of an orogastric tube for relief was unsuccessful. Intra-operatively, the stomach was found to be distended and torsed around its long axis supporting the diagnosis of Gastric dilitation-volvulus (GDV). The animal arrested and died intra-operatively and was submitted for necropsy with lesions supportive of the diagnosis of GDV. No risk factors for GDV were found to correlate between the panda and those described in domestic dogs. This case suggests that red pandas can be susceptible to this condition in captive settings.

Strong Interaction Studies with PANDA at FAIR

Science.gov (United States)

Schönning, Karin

2016-10-01

The Facility for Antiproton and Ion Research (FAIR) in Darmstadt, Germany, provides unique possibilities for a new generation of nuclear-, hadron- and atomic physics experiments. The future PANDA experiment at FAIR will offer a broad physics programme with emphasis on different aspects of hadron physics. Understanding the strong interaction in the perturbative regime remains one of the greatest challenges in contemporary physics and hadrons provide several important keys. In these proceedings, PANDA will be presented along with some high-lights of the planned physics programme.

Strong Interaction Studies with PANDA at FAIR

International Nuclear Information System (INIS)

Schönning, Karin

2016-01-01

The Facility for Antiproton and Ion Research (FAIR) in Darmstadt, Germany, provides unique possibilities for a new generation of nuclear-, hadron- and atomic physics experiments. The future PANDA experiment at FAIR will offer a broad physics programme with emphasis on different aspects of hadron physics. Understanding the strong interaction in the perturbative regime remains one of the greatest challenges in contemporary physics and hadrons provide several important keys. In these proceedings, PANDA will be presented along with some high-lights of the planned physics programme

Immobilization of wild giant panda (Ailuropoda melanoleuca) with dexmedetomidine-tiletamine-zolazepam.

Science.gov (United States)

Jin, Yipeng; Qiao, Yanchao; Liu, Xiaobin; Pu, Tianchun; Xu, Hongqian; Lin, Degui

2016-05-01

To assess the effects and utility of dexmedetomidine combined with tiletamine and zolazepam (dexMTZ) to immobilize the wild giant panda. Prospective clinical study. Seven giant pandas (Ailuropoda melanoleuca), five males and two females, aged 7-20 years and weighing 69.2-132.9 kg. Once an animal was located, prior data on the individual was reviewed and the panda's previously estimated body weight was used to calculate the volumes of drugs to administer: dexmedetomidine (dexM; 8 μg kg(-1) ; 0.5 mg mL(-1) ) and tiletamine-zolazepam (TZ; 2 mg kg(-1) ; 50 mg mL(-1) ). The mixture was injected intramuscularly (IM) using the Dan-Inject pistol system. When the panda was immobilized, it was weighed, a physical examination was performed and a blood sample collected. Every 5 minutes, the heart rate (HR), respiratory rate (fR ), rectal temperature (T), noninvasive systolic arterial pressure (SAP), capillary refill time (CRT), mucous membrane color and pulse quality were recorded. After all procedures had been completed, atipamezole (40 μg kg(-1) ) was injected IM. A single injection of dexMTZ resulted in the immobilization of all seven giant pandas. The median (range) of anesthetic agents administered was dexM 8.4 μg kg(-1) (7.3-10.5 μg kg(-1) ) and TZ 2.0 mg kg(-1) (1.8-2.5 mg kg(-1) ). The palpebral reflex was lost 8 (7-12) minutes after the injection. Most of the physiological variables remained in the acceptable range. All procedures were completed in approximately 1 hour. Six out of the seven (85.7%) giant pandas recovered smoothly; one panda had a rough recovery. DexMTZ produced a satisfactory immobilization and a smooth recovery for wild giant pandas while allowing approximately 55 minutes for planned noninvasive procedures. © 2015 Association of Veterinary Anaesthetists and the American College of Veterinary Anesthesia and Analgesia.

Habitat assessment for giant pandas in the Qinling Mountain region of China

Science.gov (United States)

Feng, Tian-Tian; Van Manen, Frank T.; Zhao, Na-Xun; Li, Ming; Wei, Fu-Wen

2009-01-01

Because habitat loss and fragmentation threaten giant pandas (Ailuropoda melanoleuca), habitat protection and restoration are important conservation measures for this endangered species. However, distribution and value of potential habitat to giant pandas on a regional scale are not fully known. Therefore, we identified and ranked giant panda habitat in Foping Nature Reserve, Guanyinshan Nature Reserve, and adjacent areas in the Qinling Mountains of China. We used Mahalanobis distance and 11 digital habitat layers to develop a multivariate habitat signature associated with 247 surveyed giant panda locations, which we then applied to the study region. We identified approximately 128 km2 of giant panda habitat in Foping Nature Reserve (43.6% of the reserve) and 49 km2 in Guanyinshan Nature Reserve (33.6% of the reserve). We defined core habitat areas by incorporating a minimum patch-size criterion (5.5 km2) based on home-range size. Percentage of core habitat area was higher in Foping Nature Reserve (41.8% of the reserve) than Guanyinshan Nature Reserve (26.3% of the reserve). Within the larger analysis region, Foping Nature Reserve contained 32.7% of all core habitat areas we identified, indicating regional importance of the reserve. We observed a negative relationship between distribution of core areas and presence of roads and small villages. Protection of giant panda habitat at lower elevations and improvement of habitat linkages among core habitat areas are important in a regional approach to giant panda conservation.

PANDA: pathway and annotation explorer for visualizing and interpreting gene-centric data.

Science.gov (United States)

Hart, Steven N; Moore, Raymond M; Zimmermann, Michael T; Oliver, Gavin R; Egan, Jan B; Bryce, Alan H; Kocher, Jean-Pierre A

2015-01-01

Objective. Bringing together genomics, transcriptomics, proteomics, and other -omics technologies is an important step towards developing highly personalized medicine. However, instrumentation has advances far beyond expectations and now we are able to generate data faster than it can be interpreted. Materials and Methods. We have developed PANDA (Pathway AND Annotation) Explorer, a visualization tool that integrates gene-level annotation in the context of biological pathways to help interpret complex data from disparate sources. PANDA is a web-based application that displays data in the context of well-studied pathways like KEGG, BioCarta, and PharmGKB. PANDA represents data/annotations as icons in the graph while maintaining the other data elements (i.e., other columns for the table of annotations). Custom pathways from underrepresented diseases can be imported when existing data sources are inadequate. PANDA also allows sharing annotations among collaborators. Results. In our first use case, we show how easy it is to view supplemental data from a manuscript in the context of a user's own data. Another use-case is provided describing how PANDA was leveraged to design a treatment strategy from the somatic variants found in the tumor of a patient with metastatic sarcomatoid renal cell carcinoma. Conclusion. PANDA facilitates the interpretation of gene-centric annotations by visually integrating this information with context of biological pathways. The application can be downloaded or used directly from our website: http://bioinformaticstools.mayo.edu/research/panda-viewer/.

A critical review of PANDAS research in the context of obsessive compulsive disorder

Directory of Open Access Journals (Sweden)

Jonathan E. Harvey

2017-10-01

Full Text Available The discovery and elaboration of pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS is emerging from a polemical status and gaining wide recognition. Current research has proposed a specific neurological pathogenesis for the disorder. This paper connects the dominant neurobiological model of obsessive compulsive disorder (OCD with the proposed pathogenesis and treatment of PANDAS. PANDAS presentation is described and an important early debate regarding anti-neuronal antibodies in the brain of PANDAS patients is outlined. Recent research on a specific immunological trigger for antibodies that cause a blood brain barrier breakdown will be discussed along with treatment for the disorder. Future avenues of research are discussed including a critique of the seminal studies in PANDAS pathology and treatment from the focal point of the dominant OCD model.

The PandaRoot framework for simulation, reconstruction and analysis

International Nuclear Information System (INIS)

Spataro, Stefano

2011-01-01

The PANDA experiment at the future facility FAIR will study anti-proton proton and anti-proton nucleus collisions in a beam momentum range from 2 GeV/c up to 15 GeV/c. The PandaRoot framework is part of the FairRoot project, a common software framework for the future FAIR experiments, and is currently used to simulate detector performances and to evaluate different detector concepts. It is based on the packages ROOT and Virtual MonteCarlo with Geant3 and Geant4. Different reconstruction algorithms for tracking and particle identification are under development and optimization, in order to achieve the performance requirements of the experiment. In the central tracker a first track fit is performed using a conformal map transformation based on a helix assumption, then the track is used as input for a Kalman Filter (package genfit), using GEANE as track follower. The track is then correlated to the pid detectors (e.g. Cerenkov detectors, EM Calorimeter or Muon Chambers) to evaluate a global particle identification probability, using a Bayesian approach or multivariate methods. Further implemented packages in PandaRoot are: the analysis tools framework Rho, the kinematic fitter package for vertex and mass constraint fits, and a fast simulation code based upon parametrized detector responses. PandaRoot was also tested on an Alien-based GRID infrastructure. The contribution will report about the status of PandaRoot and show some example results for analysis of physics benchmark channels.

Fatal Toxoplasma gondii infection in the giant panda.

Science.gov (United States)

Ma, Hongyu; Wang, Zedong; Wang, Chengdong; Li, Caiwu; Wei, Feng; Liu, Quan

2015-01-01

Toxoplasma gondii can infect nearly all warm-blooded animals. We report an acute fatal T. gondii infection in the endangered giant panda (Ailuropoda melanoleuca) in a zoo in China, characterized by acute gastroenteritis and respiratory symptoms. T. gondii infection was confirmed by immunological and molecular methods. Multilocus nested PCR-RFLP revealed clonal type I at the SAG1 and c29-2 loci, clonal type II at the SAG2, BTUB, GRA6, c22-8, and L358 loci, and clonal type III at the alternative SAG2 and SAG3 loci, thus, a potential new genotype of T. gondii in the giant panda. Other possible pathogens were not detected. To our knowledge, this is the first report of clinical toxoplasmosis in a giant panda. © H. Ma et al., published by EDP Sciences, 2015.

Double {Lambda}-hypernuclei at the PANDA experiment

Energy Technology Data Exchange (ETDEWEB)

Sanchez Lorente, Alicia, E-mail: a.sanchez@gsi.de [Helmholtz Institut Mainz (Germany); Collaboration: P-bar ANDA Collaboration

2012-12-15

Hypernuclear research will be one of the main topics addressed by the PANDA experiment at the planned Facility for Antiproton and Ion Research FAIR at Darmstadt (Germany). Thanks to the use of stored p-bar beams, copious production of double {Lambda} hypernuclei is expected at the PANDA experiment, which will enable high precision {gamma} spectroscopy of such nuclei for the first time. At PANDA excited states of {Xi}{sup }- hypernuclei will be used as a starting point for the formation of double {Lambda} hypernuclei. In order to predict the yield of particle stable double hypernuclei a microcanonical decay model was developed. For the detection of these nuclei, a devoted hypernuclear detector setup is planned. This set-up consists, in addition to the general purpose of the PANDA set-up, of a primary nuclear target for the production of {Xi}{sup -} + {Xi}-bar pairs, a secondary active target for the hypernuclei formation and the identification of associated decay products and a germanium array detector to perform {gamma} spectroscopy. Furthermore, the presence of {Xi}-bar can be used as an alternative to tag the strangeness in the {Xi}{sup -} + {Xi}-bar. All systems need to operate in the presence of a high magnetic field and a large hadronic background. In the present talk details concerning simulations, the identification procedure of double hypernuclei and the suppression of background will be presented. In addition, the present status of the detector developments for this programme will be briefly given.

Actuación de la enfermería en la creación del servicio de lactancia del Hospital Jesus (1935-1938)

OpenAIRE

Rodrigues Pimenta, A.; Moreira, A.; Neves de Sant’Anna Menezes, A.; Porto, F.; Braga de Santana, S.

2010-01-01

El presente estudio tiene como objeto la implantación del servicio de lactario en el Hospital Jesús y tiene por delimitación temporal el periodo de 1935-1938, que se justifica por la primera gestión del Servicio de Enfermería del Hospital Jesús, actual Hospital Municipal Jesús. La alimentación del niño merece cuidados especiales, principalmente en el primer año de vida. Objetivos: describir las políticas de alimentación en el Distrito Federal y analizar las circunstancias para la implantación...

Integration of PanDA workload management system with Titan supercomputer at OLCF

CERN Document Server

AUTHOR|(INSPIRE)INSPIRE-00300320; Klimentov, Alexei; Oleynik, Danila; Panitkin, Sergey; Petrosyan, Artem; Vaniachine, Alexandre; Wenaus, Torre; Schovancova, Jaroslava

2015-01-01

The PanDA (Production and Distributed Analysis) workload management system (WMS) was developed to meet the scale and complexity of LHC distributed computing for the ATLAS experiment. While PanDA currently distributes jobs to more than 100,000 cores at well over 100 Grid sites, next LHC data taking run will require more resources than Grid computing can possibly provide. To alleviate these challenges, ATLAS is engaged in an ambitious program to expand the current computing model to include additional resources such as the opportunistic use of supercomputers. We will describe a project aimed at integration of PanDA WMS with Titan supercomputer at Oak Ridge Leadership Computing Facility (OLCF). Current approach utilizes modi ed PanDA pilot framework for job submission to Titan's batch queues and local data management, with light-weight MPI wrappers to run single threaded workloads in parallel on Titan's multi-core worker nodes. It also gives PanDA new capability to collect, in real time, information about unused...

Integration of PanDA workload management system with Titan supercomputer at OLCF

CERN Document Server

Panitkin, Sergey; The ATLAS collaboration; Klimentov, Alexei; Oleynik, Danila; Petrosyan, Artem; Schovancova, Jaroslava; Vaniachine, Alexandre; Wenaus, Torre

2015-01-01

The PanDA (Production and Distributed Analysis) workload management system (WMS) was developed to meet the scale and complexity of LHC distributed computing for the ATLAS experiment. While PanDA currently uses more than 100,000 cores at well over 100 Grid sites with a peak performance of 0.3 petaFLOPS, next LHC data taking run will require more resources than Grid computing can possibly provide. To alleviate these challenges, ATLAS is engaged in an ambitious program to expand the current computing model to include additional resources such as the opportunistic use of supercomputers. We will describe a project aimed at integration of PanDA WMS with Titan supercomputer at Oak Ridge Leadership Computing Facility (OLCF). Current approach utilizes modified PanDA pilot framework for job submission to Titan's batch queues and local data management, with light-weight MPI wrappers to run single threaded workloads in parallel on Titan's multi-core worker nodes. It also gives PanDA new capability to collect, in real tim...

Global heterogeneous resource harvesting: the next-generation PanDA Pilot for ATLAS

CERN Document Server

Nilsson, Paul; The ATLAS collaboration

2017-01-01

The Production and Distributed Analysis system (PanDA), used for workload management in the ATLAS Experiment for over a decade, has in recent years expanded its reach to diverse new resource types such as HPCs, and innovative new workflows such as the Event Service. PanDA meets the heterogeneous resources it harvests in the PanDA pilot, which has embarked on a next-generation reengineering to efficiently integrate and exploit the new platforms and workflows. The new modular architecture is the product of a year of design and prototyping in conjunction with the design of a completely new component, Harvester, that will mediate a richer flow of control and information between pilot and PanDA. Harvester will enable more intelligent and dynamic matching between processing tasks and resources, with an initial focus on HPCs, simplifying the operator and user view of a PanDA site but internally leveraging deep information gathering on the resource to accrue detailed knowledge of a site's capabilities and dynamic sta...

Global heterogeneous resource harvesting: the next-generation PanDA pilot for ATLAS

CERN Document Server

Nilsson, Paul; The ATLAS collaboration

2017-01-01

The Production and Distributed Analysis system (PanDA), used for workload management in the ATLAS Experiment for over a decade, has in recent years expanded its reach to diverse new resource types such as HPCs, and innovative new workflows such as the event service. PanDA meets the heterogeneous resources it harvests in the PanDA pilot, which has embarked on a next-generation reengineering to efficiently integrate and exploit the new platforms and workflows. The new modular architecture is the product of a year of design and prototyping in conjunction with the design of a completely new component, Harvester, that will mediate a richer flow of control and information between pilot and PanDA. Harvester will enable more intelligent and dynamic matching between processing tasks and resources, with an initial focus on HPCs, simplifying the operator and user view of a PanDA site but internally leveraging deep information gathering on the resource to accrue detailed knowledge of a site's capabilities and dynamic sta...

HEMATOLOGY, SERUM BIOCHEMISTRY, AND URINALYSIS VALUES IN THE ADULT GIANT PANDA ( AILUROPODA MELANOLEUCA).

Science.gov (United States)

Burrell, Caitlin; Zhang, Hemin; Li, Desheng; Wang, Chengdong; Li, Caiwu; Aitken-Palmer, Copper

2017-12-01

The giant panda ( Ailuropoda melanoleuca) is a high-profile threatened species with individuals in captivity worldwide. As a result of advances in captive animal management and veterinary medicine, the ex situ giant panda population is aging, and improved understanding of age-related changes is necessary. Urine and blood samples were collected in April and July 2015 and analyzed for complete blood count, serum biochemistry, and biochemical and microscopic urine analysis for all individuals sampled ( n = 7, 7-16 yr of age) from giant panda housed at the China Research and Conservation Centre for the Giant Panda in Bifengxia, Sichuan Province, China. Hematology and serum biochemistry values were similar to those previously reported for giant panda aged 2-20 yr and to Species360 (formerly International Species Information System) values. Urine was overall dilute (urine specific gravity range: 1.001-1.021), acellular, and acidic (pH range: 6-7). This is the first report of hematologic and serum biochemistry, with associated urinalysis values, in the giant panda aged 7-16 yr.

ANIMAL PHYSIOLOGY. Exceptionally low daily energy expenditure in the bamboo-eating giant panda.

Science.gov (United States)

Nie, Yonggang; Speakman, John R; Wu, Qi; Zhang, Chenglin; Hu, Yibo; Xia, Maohua; Yan, Li; Hambly, Catherine; Wang, Lu; Wei, Wei; Zhang, Jinguo; Wei, Fuwen

2015-07-10

The carnivoran giant panda has a specialized bamboo diet, to which its alimentary tract is poorly adapted. Measurements of daily energy expenditure across five captive and three wild pandas averaged 5.2 megajoules (MJ)/day, only 37.7% of the predicted value (13.8 MJ/day). For the wild pandas, the mean was 6.2 MJ/day, or 45% of the mammalian expectation. Pandas achieve this exceptionally low expenditure in part by reduced sizes of several vital organs and low physical activity. In addition, circulating levels of thyroid hormones thyroxine (T4) and triiodothyronine (T3) averaged 46.9 and 64%, respectively, of the levels expected for a eutherian mammal of comparable size. A giant panda-unique mutation in the DUOX2 gene, critical for thyroid hormone synthesis, might explain these low thyroid hormone levels. A combination of morphological, behavioral, physiological, and genetic adaptations, leading to low energy expenditure, likely enables giant pandas to survive on a bamboo diet. Copyright © 2015, American Association for the Advancement of Science.

The first skull of the earliest giant panda

OpenAIRE

Jin, Changzhu; Dong, Wei; Hunt, Jr., Robert M.; Liu, Jinyi; Jaeger, Marc; Zhu, Qizhi

2007-01-01

Fossils of the giant panda Ailuropoda (Order Carnivora, Family Ursidae) are largely isolated teeth, mandibles, and a few rare skulls, known from the late Pliocene to late Pleistocene in China and Southeast Asia. Much of this material represents a Pleistocene chronospecies, Ailuropoda baconi, an animal larger than the living giant panda, Ailuropoda melanoleuca. The earliest certain record of Ailuropoda is the late Pliocene chronospecies, Ailuropoda microta, smaller than either A. baconi or A. ...

Long Non-coding RNA, PANDA, Contributes to the Stabilization of p53 Tumor Suppressor Protein.

Science.gov (United States)

Kotake, Yojiro; Kitagawa, Kyoko; Ohhata, Tatsuya; Sakai, Satoshi; Uchida, Chiharu; Niida, Hiroyuki; Naemura, Madoka; Kitagawa, Masatoshi

2016-04-01

P21-associated noncoding RNA DNA damage-activated (PANDA) is induced in response to DNA damage and represses apoptosis by inhibiting the function of nuclear transcription factor Y subunit alpha (NF-YA) transcription factor. Herein, we report that PANDA affects regulation of p53 tumor-suppressor protein. U2OS cells were transfected with PANDA siRNAs. At 72 h post-transfection, cells were subjected to immunoblotting and quantitative reverse transcription-polymerase chain reaction. Depletion of PANDA was associated with decreased levels of p53 protein, but not p53 mRNA. The stability of p53 protein was markedly reduced by PANDA silencing. Degradation of p53 protein by silencing PANDA was prevented by treatment of MG132, a proteasome inhibitor. Moreover, depletion of PANDA prevented accumulation of p53 protein, as a result of DNA damage, induced by the genotoxic agent etoposide. These results suggest that PANDA stabilizes p53 protein in response to DNA damage, and provide new insight into the regulatory mechanisms of p53. Copyright© 2016 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.

Detection of understory bamboo in giant panda habitats using an indirect remote sensing approach

NARCIS (Netherlands)

Bian, B.M.; Wang, T.; Liu, Y.F.; Fei, T.; Skidmore, A.K.

2007-01-01

The bamboo is the exclusive food of the wild giant pandas. Detection of the bamboo forest in giant panda habitat will help scientists further understand the spatial distribution pattern of giant pandas and their habitats. Moreover, it provides crucial scientific evidence for estimating habitat

Assessing vulnerability of giant pandas to climate change in the Qinling Mountains of China.

Science.gov (United States)

Li, Jia; Liu, Fang; Xue, Yadong; Zhang, Yu; Li, Diqiang

2017-06-01

Climate change might pose an additional threat to the already vulnerable giant panda ( Ailuropoda melanoleuca ). Effective conservation efforts require projections of vulnerability of the giant panda in facing climate change and proactive strategies to reduce emerging climate-related threats. We used the maximum entropy model to assess the vulnerability of giant panda to climate change in the Qinling Mountains of China. The results of modeling included the following findings: (1) the area of suitable habitat for giant pandas was projected to decrease by 281 km 2 from climate change by the 2050s; (2) the mean elevation of suitable habitat of giant panda was predicted to shift 30 m higher due to climate change over this period; (3) the network of nature reserves protect 61.73% of current suitable habitat for the species, and 59.23% of future suitable habitat; (4) current suitable habitat mainly located in Chenggu, Taibai, and Yangxian counties (with a total area of 987 km 2 ) was predicted to be vulnerable. Assessing the vulnerability of giant panda provided adaptive strategies for conservation programs and national park construction. We proposed adaptation strategies to ameliorate the predicted impacts of climate change on giant panda, including establishing and adjusting reserves, establishing habitat corridors, improving adaptive capacity to climate change, and strengthening monitoring of giant panda.

En el Cincuentenario del Hospital Santa Clara

Directory of Open Access Journals (Sweden)

Gilberto Rueda Pérez

1992-12-01

Full Text Available

El 16 de julio de 1942 nace el Hospital Sanatorio Antituberculoso Santa Clara en Santafé de Bogotá.
Un siglo atrás, casi a la fecha, en 1843, nace en Alemania Roberto Koch, quien, 60 años antes de la fundación del Hospital, el 24 de marzo de 1882, presenta al mundo el descubrimiento del Micobacterium Tuberculosis, germen causante de la enfermedad que ataca alhombre desde sus más remotos orígenes y que aún nos acompaña, especialmente en los países subdesarrollados, causando severo impacto en la salud de las poblaciones más necesitadas, apesar de los grandes avances alcanzados en el campo de la Medicina a nivel mundial.
Por haber sido destinado el Hospital altratamiento de los tuberculosos, destino que aún conserva primordialmente aunque, como se verá posteriormente, sus camas reciben enfermos de medicina general dada la evolución de los tratamientos y la modernización de los esquemas terapéuticos, se justifica ampliamente mencionar aquí los principales avances relacionados con el control de la Tuberculosis a través de los tiempos hasta la fundación del Hospital.

Estos se pueden resumir así:

• 'HIPOCRATES (460-377 a. C.:describe la consunción y la llama tisis; lanza el concepto de herencia que perdura por siglos.
• ARISTOTELES(324-284a. C.:habla del contagio a través de la respiración.
• CELSO (siglo I a. C.: describe el tubérculo y señala tres formas de consunción: atrofia, caquexia y tisis.
• GALENO(181-261 d. C.: la agrupa con otras enfermedades transmisibles: la peste, la sarna, etc.
• EDADMEDIA(sigloVII alXIIId. C.:se destaca únicamente como aporte nuevo Maimonides, filósofo judío radicado en Granada (11351204,quien describe la tisis de los animales.

Posteriormente Girolamo Fracastoro (1478-1553, nacido en Verona,la asimila a la viruela y lanza la teoría microbiana.

• PARACELSO(1493-1541pregona que: los

• Evidence of a false thumb in a fossil carnivore clarifies the evolution of pandas

  OpenAIRE

  Salesa, Manuel J.; Antón, Mauricio; Peigné, Stéphane; Morales, Jorge

  2005-01-01

  The “false thumb” of pandas is a carpal bone, the radial sesamoid, which has been enlarged and functions as an opposable thumb. If the giant panda (Ailuropoda melanoleuca) and the red panda (Ailurus fulgens) are not closely related, their sharing of this adaptation implies a remarkable convergence. The discovery of previously unknown postcranial remains of a Miocene red panda relative, Simocyon batalleri, from the Spanish site of Batallones-1 (Madrid), now shows that this animal had a false t...

• 75 FR 80110 - Panda Power LLC, Receipt of Petition for Decision of Inconsequential Noncompliance

  Science.gov (United States)

  2010-12-21

  ... Panda Power LLC (Panda Power),\\1\\ has determined that High Intensity Discharge (HID) lighting kits \\2... of Federal Motor Vehicle Safety Standard (FMVSS) No. 108, Lamps, Reflective Devices, and Associated.... \\2\\ Panda Power's high-intensity lighting (HID kits each contained 2 lamps, 2 lamp ballasts and a...

• Capilla del Hospital Municipal de Mannheim, Alemania

  Directory of Open Access Journals (Sweden)

  Mutschler, C.

  1969-07-01

  Full Text Available This building was completed when the Municipal Hospital of Mannheim was enlarged and became a Faculty of Medicine. It serves equally well for catholic and protestant religious services. The visitor reaches the church after traversing a gently inclined path: the main feature that holds his attention on entering is the altar and sacristy zone. Advancing up a ramp a gallery is reached, which enables sick people on wheelchairs, or in beds, to participate in the liturgical acts. The main materials utilised have been untreated brick and concrete.Construida a raíz de la ampliación del Hospital Municipal de Mannheim y su conversión en Facultad de Medicina, sirve indistintamente para la celebración de los actos litúrgicos de ambas confesiones. El visitante, por un camino suavemente inclinado, ingresa en el interior del edificio, cuyo núcleo focal está constituido por la zona del altar y las sacristías. Subiendo por una rampa se accede a una galería que permite el que los enfermos, en sillones con ruedas, o en Ja cama, etc., puedan participar desde allí en los actos litúrgicos. Los materiales fundamentales empleados son: ladrillo a cara vista y hormigón, igualmente visto.

• China's endemic vertebrates sheltering under the protective umbrella of the giant panda.

  Science.gov (United States)

  Li, Binbin V; Pimm, Stuart L

  2016-04-01

  The giant panda attracts disproportionate conservation resources. How well does this emphasis protect other endemic species? Detailed data on geographical ranges are not available for plants or invertebrates, so we restrict our analyses to 3 vertebrate taxa: birds, mammals, and amphibians. There are gaps in their protection, and we recommend practical actions to fill them. We identified patterns of species richness, then identified which species are endemic to China, and then which, like the panda, live in forests. After refining each species' range by its known elevational range and remaining forest habitats as determined from remote sensing, we identified the top 5% richest areas as the centers of endemism. Southern mountains, especially the eastern Hengduan Mountains, were centers for all 3 taxa. Over 96% of the panda habitat overlapped the endemic centers. Thus, investing in almost any panda habitat will benefit many other endemics. Existing panda national nature reserves cover all but one of the endemic species that overlap with the panda's distribution. Of particular interest are 14 mammal, 20 bird, and 82 amphibian species that are inadequately protected. Most of these species the International Union for Conservation of Nature currently deems threatened. But 7 mammal, 3 bird, and 20 amphibian species are currently nonthreatened, yet their geographical ranges are pandas are absent and where there are no national nature reserves. The others concentrate in Yunnan, Nan Mountains, and Hainan. Here, 10 prefectures might establish new protected areas or upgrade local nature reserves to national status. © 2015 Society for Conservation Biology.

PD2P: PanDA Dynamic Data Placement for ATLAS

International Nuclear Information System (INIS)

Maeno, T; Panitkin, S; De, K

2012-01-01

The PanDA (Production and Distributed Analysis) system plays a key role in the ATLAS distributed computing infrastructure. PanDA is the ATLAS workload management system for processing all Monte-Carlo (MC) simulation and data reprocessing jobs in addition to user and group analysis jobs. The PanDA Dynamic Data Placement (PD2P) system has been developed to cope with difficulties of data placement for ATLAS. We will describe the design of the new system, its performance during the past year of data taking, dramatic improvements it has brought about in the efficient use of storage and processing resources, and plans for the future.

PANDA experiment and International Standard Problem for passive cooling systems for afterheat removal; PANDA-Versuch und Internationales Standardproblem zu passiven Kuehlsystemen fuer die Nachwaermeabfuhr

Energy Technology Data Exchange (ETDEWEB)

Yadigaroglu, G.; Aksan, N.S. [Paul Scherrer Inst. (PSI), Villigen (Switzerland). Lab. fuer Thermohydraulik

1999-09-03

In the context of OECD/NEA, Paul Scherrer Institut (PSI) is working on an International Standard Problem which is to provide information on the efficiency and use of computer program systems for passive afterheat removal systems. The PANDA test facility of PSI was designed for these investigations. A six-phase PANDA experiment provides a basis for pre-calculation and recalculation of selected phases covering a limited number of system-typical operating states and phenomena. The experiment was specified and carried out in the year under report. [Deutsch] Im Rahmen der OECD/NEA fuehrt das Paul Scherrer Institut (PSI) ein Internationales Standardproblem durch, das Aufschluss ueber die Leistungsfaehigkeit und Handhabung von Computer-Programmsystemen geben soll, die im Zusammenhang mit passiven Nachwaerme-Abfuhrsystemen eingesetzt werden. Die Versuchsanlage PANDA am PSI ist speziell auf die Untersuchung derartiger Systeme ausgerichtet. Ein PANDA-Versuch in sechs Phasen liefert den teilnehmenden Organisationen die Basis fuer Voraus- und Nachrechnungen einzelner oder mehrerer Phasen, die jeweils eine begrenzte Anzahl von systemtypischen Betriebszustaenden und Phaenomenen abdecken. Im Berichtsjahr wurde der Versuch spezifiziert und gefahren. (orig.)

Recent Improvements in the ATLAS PanDA Pilot

International Nuclear Information System (INIS)

Nilsson, P; De, K; Bejar, J Caballero; Maeno, T; Potekhin, M; Wenaus, T; Compostella, G; Contreras, C; Dos Santos, T

2012-01-01

The Production and Distributed Analysis system (PanDA) in the ATLAS experiment uses pilots to execute submitted jobs on the worker nodes. The pilots are designed to deal with different runtime conditions and failure scenarios, and support many storage systems. This talk will give a brief overview of the PanDA pilot system and will present major features and recent improvements including CernVM File System integration, the job retry mechanism, advanced job monitoring including JEM technology, and validation of new pilot code using the HammerCloud stress-testing system. PanDA is used for all ATLAS distributed production and is the primary system for distributed analysis. It is currently used at over 130 sites worldwide. We analyze the performance of the pilot system in processing LHC data on the OSG, EGI and Nordugrid infrastructures used by ATLAS, and describe plans for its further evolution.

Simulation and event reconstruction inside the PandaRoot framework

International Nuclear Information System (INIS)

Spataro, S

2008-01-01

The PANDA detector will be located at the future GSI accelerator FAIR. Its primary objective is the investigation of strong interaction with anti-proton beams, in the range up to 15 GeV/c as momentum of the incoming anti-proton. The PANDA offline simulation framework is called 'PandaRoot', as it is based upon the ROOT 5.14 package. It is characterized by a high versatility; it allows to perform simulation and analysis, to run different event generators (EvtGen, Pluto, UrQmd), different transport models (Geant3, Geant4, Fluka) with the same code, thus to compare the results simply by changing few macro lines without recompiling at all. Moreover auto-configuration scripts allow installing the full framework easily in different Linux distributions and with different compilers (the framework was installed and tested in more than 10 Linux platforms) without further manipulation. The final data are in a tree format, easily accessible and readable through simple clicks on the root browsers. The presentation will report on the actual status of the computing development inside the PandaRoot framework, in terms of detector implementation and event reconstruction

Panda, Dr Subrat Kumar

Indian Academy of Sciences (India)

Panda, Dr Subrat Kumar M.B.B.S. (Utkal), M.D. (Path.) (AIIMS), FNA. Date of birth: 18 November 1954. Specialization: Liver Pathology, Viral Hepatitis and Molecular Biology/Virology Address: Professor, Department of Pathology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029, U.T.. Contact:

PanDA for COMPASS at JINR

Science.gov (United States)

Petrosyan, A. Sh.

2016-09-01

PanDA (Production and Distributed Analysis System) is a workload management system, widely used for data processing at experiments on Large Hadron Collider and others. COMPASS is a high-energy physics experiment at the Super Proton Synchrotron. Data processing for COMPASS runs locally at CERN, on lxbatch, the data itself stored in CASTOR. In 2014 an idea to start running COMPASS production through PanDA arose. Such transformation in experiment's data processing will allow COMPASS community to use not only CERN resources, but also Grid resources worldwide. During the spring and summer of 2015 installation, validation and migration work is being performed at JINR. Details and results of this process are presented in this paper.

Prevalencia del tabaquismo en los trabajadores de un hospital

Directory of Open Access Journals (Sweden)

Arévalo Alonso José Miguel

1997-01-01

Full Text Available FUNDAMENTO: Sobre tabaquismo se han realizado muchos estudios tanto en España como en otros países. El objetivo de esta encuesta es valorar la prevalencia de tabaquismo en una muestra representativa de trabajadores del hospital y su asociación con la edad, sexo, estamento profesional y actitudes. MÉTODOS: Después de un estudio piloto, se realizó una encuesta en una muestra representativa y aleatoria (n=360 de trabajadores del hospital, a los que se les preguntó por sus actitudes al hábito tabáquico, clasificados por edad, sexo y estamentos. RESULTADOS: El porcentaje total de fumadores es de 36.4%, pero no se han encontrado diferencias estadísticamente significativas ni por sexo ni grupo de edad. Los estamentos con mayor porcentaje de fumadores son ATS/DUE y Administrativos. El 42.8% de los no fumadores declaran haberlo hecho antes, siendo los estamentos de ATS/DUE, Administrativos y Facultativos los que mostraron el mayor porcentaje. Un 40.5% de fumadores declaran estar dispuestos a dejar el hábito, mientras el grupo de personas mayores de 50 años se muestran más resistentes. La mayoría de fumadores de cigarrillos señalan que fuman en el hospital. La mayor parte de ellos son fumadores intermedios (10-20 cigarrillos/día y lo llevan haciendo muchos años. La mayor parte de los exfumadores declaran haber dejado el hábito en los últimos años. CONCLUSIONES: Estos resultados demuestran que un gran porcentaje de trabajadores del hospital son fumadores. Sin embargo, existe un importante número que está dispuestos a dejarlo. Por ello, animamos a estas personas a que dejen de fumar y ayudarles por medio de diversas acciones tales como: consulta de tratamiento del tabaquismo, consejo médico y educación para la salud. Proponemos declarar al hospital como "HOSPITAL SIN TABACO" para el año 2000, lo cual incluye a trabajadores, pacientes y visitas, de acuerdo con la estrategia de la OMS "Salud para todos".

Atmospheric deposition exposes Qinling pandas to toxic pollutants.

Science.gov (United States)

Chen, Yi-Ping; Zheng, Ying-Juan; Liu, Qiang; Song, Yi; An, Zhi-Sheng; Ma, Qing-Yi; Ellison, Aaron M

2017-03-01

The giant panda (Ailuropoda melanoleuca) is one of the most endangered animals in the world, and it is recognized worldwide as a symbol for conservation. A previous study showed that wild and captive pandas, especially those of the Qinling subspecies, were exposed to toxicants in their diet of bamboo; the ultimate origin of these toxicants is unknown. Here we show that atmospheric deposition is the most likely origin of heavy metals and persistent organic pollutants (POPs) in the diets of captive and wild Qinling pandas. Average atmospheric deposition was 199, 115, and 49 g·m -2 ·yr -1 in the center of Xi'an City, at China's Shaanxi Wild Animal Research Center (SWARC), and at Foping National Nature Reserve (FNNR), respectively. Atmospheric deposition of heavy metals (As, Cd, Cr, Pb, Hg, Co, Cu, Zn, Mn, and Ni) and POPs was highest at Xi'an City, intermediate at SWARC, and lowest at FNNR. Soil concentrations of the aforementioned heavy metals other than As and Zn also were significantly higher at SWARC than at FNNR. Efforts to conserve Qinling pandas may be compromised by air pollution attendant to China's economic development. Improvement of air quality and reductions of toxic emissions are urgently required to protect China's iconic species. © 2017 by the Ecological Society of America.

Dietary resources shape the adaptive changes of cyanide detoxification function in giant panda (Ailuropoda melanoleuca)

OpenAIRE

He Huang; Shangmian Yie; Yuliang Liu; Chengdong Wang; Zhigang Cai; Wenping Zhang; Jingchao Lan; Xiangming Huang; Li Luo; Kailai Cai; Rong Hou; Zhihe Zhang

2016-01-01

The functional adaptive changes in cyanide detoxification in giant panda appear to be response to dietary transition from typical carnivore to herbivorous bear. We tested the absorption of cyanide contained in bamboo/bamboo shoots with a feeding trial in 20 adult giant pandas. We determined total cyanide content in bamboo shoots and giant panda?s feces, levels of urinary thiocyanate and tissue rhodanese activity using color reactions with a spectrophotometer. Rhodanese expression in liver and...

An Investigation of Cellulose Digesting Bacteria in the Panda Gut Microbiome

Science.gov (United States)

Lu, M.; Leung, F. C.

2014-12-01

The Giant Panda (Ailuropoda melanoleuca) diet consists primarily of bamboo leaves, stems and shoots. However, the Giant Panda lacks genes for the enzymes needed to digest cellulose, the core component of bamboo. Thus, it is hypothesized that the cellulolytic digestion necessary for maintaining the Giant Panda diet is carried out by microbial symbionts in the panda gut microbiota. Fecal microbiota is used as surrogate index for gut microbiota since the Giant Panda is listed by the World Conservation Union as a Threatened Species. Two bacterial isolates with potential cellulolytic activity were isolated from Giant Panda fecal samples and cultured on selective media CMC (carboxymethyl cellulose) agar and CMC-Congo Red agar using various methods of inoculation. After incubation, clearance zones around colonies were observed and used as qualitative assays for cellulose digestion. Polymerase chain reaction amplification of the 16S rRNA gene was completed and species identification was done based on the BLAST result of 16S rRNA sequence obtained using Sanger sequencing. Once the cellulase activity is confirmed, genomic DNA of the bacteria will be extracted and used for whole genome shotgun sequencing. Illumina next generation sequencing platform will be adopted as it yields high-throughput information, providing a better understanding of cellulose digestion and the molecular genetic pathways to renewable sources of biofuels. Researchers have identified multiple cellulose-digesting microbes in the Giant Panda gut, but few have applied such bacteria in converting cellulose into glucose to create biofuel. Cellulosic ethanol, a biofuel, is produced through the fermentation of lignocellulosic biomasses. This anaerobic process is aided by cellulose-digesting enzymes. Certain microbes, such as those present in the Giant Panda gut, can produce enzymes that cleave the glycosidic bonds of cellulose (C6H10O5) into glucose molecules (C6H12O6), which can then be fermented into ethanol

from the Giant Panda

African Journals Online (AJOL)

STORAGESEVER

2009-06-03

Jun 3, 2009 ... 1College of Life Science, China West Normal University, 44# Yuying Road, 637002, Nanchong, China. 2Zhan Jiang educational ... in Escherichia coli and the RPS28 protein fusioned with the N-terminally GST -tagged protein gave rise ... long Conservation Center of the Giant Panda, Sichuan, China. The.

Large-scale, multi-compartment tests in PANDA for LWR-containment analysis and code validation

International Nuclear Information System (INIS)

Paladino, Domenico; Auban, Olivier; Zboray, Robert

2006-01-01

The large-scale thermal-hydraulic PANDA facility has been used for the last years for investigating passive decay heat removal systems and related containment phenomena relevant for next-generation and current light water reactors. As part of the 5. EURATOM framework program project TEMPEST, a series of tests was performed in PANDA to experimentally investigate the distribution of hydrogen inside the containment and its effect on the performance of the Passive Containment Cooling System (PCCS) designed for the Economic Simplified Boiling Water Reactor (ESBWR). In a postulated severe accident, a large amount of hydrogen could be released in the Reactor Pressure Vessel (RPV) as a consequence of the cladding Metal- Water (M-W) reaction and discharged together with steam to the Drywell (DW) compartment. In PANDA tests, hydrogen was simulated by using helium. This paper illustrates the results of a TEMPEST test performed in PANDA and named as Test T1.2. In Test T1.2, the gas stratification (steam-helium) patterns forming in the large-scale multi-compartment PANDA DW, and the effect of non-condensable gas (helium) on the overall behaviour of the PCCS were identified. Gas mixing and stratification in a large-scale multi-compartment system are currently being further investigated in PANDA in the frame of the OECD project SETH. The testing philosophy in this new PANDA program is to produce data for code validation in relation to specific phenomena, such as: gas stratification in the containment, gas transport between containment compartments, wall condensation, etc. These types of phenomena are driven by buoyant high-momentum injections (jets) and/or low momentum injection (plumes), depending on the transient scenario. In this context, the new SETH tests in PANDA are particularly valuable to produce an experimental database for code assessment. This paper also presents an overview of the PANDA SETH tests and the major improvements in instrumentation carried out in the PANDA

Eventos adversos derivados del cuidado brindado en la Unidad de Cuidados Intensivos Adultos del Hospital Universidad del Norte. Barranquilla (Colombia

Directory of Open Access Journals (Sweden)

Elizabeth Villarreal Cantillo

2014-01-01

Full Text Available Objetivo: Determinar los eventos adversos derivados del cuidado brindado en la Unidad de Cuidados Intensivos del Hospital Universidad del Norte (en Barranquilla en el periodo enero-diciembre de 2012. Materiales y métodos: Estudio descriptivo transversal retrospectivo. La muestra se obtuvo mediante un muestreo sistemático, a partir de un listado ordenado de todas las personas ingresadas al Hospital Universidad del Norte (HUN en los servicios de Urgencias, Hospitalización, Cirugía, UCI Adultos, UCI Neonatal, Gineco-Obstetricia, Consulta Externa, Radiología y Laboratorio que hubieran sufrido algún evento adverso ocurrido entre enero a diciembre de 2012. La información se obtuvo mediante la base de datos del Hospital Universidad del Norte. Para el análisis se utilizó Microsoft Excel 2010. Resultados: Durante 2012 se presentaron 130 (25 % casos de eventos adversos; siendo el segundo servicio con mayor número de eventos, después de Hospitalización. Las tres primeras causas de eventos adversos fueron: la infección nosocomial, con un 25 %; las úlceras por presión, con en un 18 %, y la neumonía asociada a ventilación mecánica, con un 16 %. Conclusiones: Los eventos adversos que más son reportados en las unidades de cuidados intensivos adultos son aquellos que ocurren cuando hay una mayor intervención en el paciente. Condiciona la aparición de eventos adversos un personal sanitario con déficit de conocimientos y falta de preparación. La ocurrencia de estos eventos adversos pone en peligro la vida de los seres humanos, debido a que empeoran su condición, produce sobrecosto y al profesional le genera sobrecarga laboral y afectiva.

Next Generation PanDA Pilot for ATLAS and Other Experiments

CERN Document Server

Nilsson, P; The ATLAS collaboration; Caballero Bejar, J; De, K; Hover, J; Love, P; Maeno, T; Medrano Llamas, R; Walker, R; Wenaus, T

2013-01-01

The Production and Distributed Analysis system (PanDA) has been in use in the ATLAS Experiment since 2005. It uses a sophisticated pilot system to execute submitted jobs on the worker nodes. While originally designed for ATLAS, the PanDA Pilot has recently been refactored to facilitate use outside of ATLAS. Experiments are now handled as plug-ins such that a new PanDA Pilot user only has to implement a set of prototyped methods in the plug-in classes, and provide a script that configures and runs the experiment specific payload. We will give an overview of the Next Generation PanDA Pilot system and will present major features and recent improvements including live user payload debugging, data access via the Federated XRootD system, stage-out to alternative storage elements, support for the new ATLAS DDM system (Rucio), and an improved integration with glExec, as well as a description of the experiment specific plug-in classes. The performance of the pilot system in processing LHC data on the OSG, LCG and Nord...

Next Generation PanDA Pilot for ATLAS and Other Experiments

CERN Document Server

Nilsson, P; The ATLAS collaboration; Caballero Bejar, J; De, K; Hover, J; Love, P; Maeno, T; Medrano Llamas, R; Walker, R; Wenaus, T

2014-01-01

The Production and Distributed Analysis system (PanDA) has been in use in the ATLAS Experiment since 2005. It uses a sophisticated pilot system to execute submitted jobs on the worker nodes. While originally designed for ATLAS, the PanDA Pilot has recently been refactored to facilitate use outside of ATLAS. Experiments are now handled as plug-ins such that a new PanDA Pilot user only has to implement a set of prototyped methods in the plug-in classes, and provide a script that configures and runs the experiment specific payload. We will give an overview of the Next Generation PanDA Pilot system and will present major features and recent improvements including live user payload debugging, data access via the Federated XRootD system, stage-out to alternative storage elements, support for the new ATLAS DDM system (Rucio), and an improved integration with glExec, as well as a description of the experiment specific plug-in classes. The performance of the pilot system in processing LHC data on the OSG, LCG and Nord...

The next generation of the ATLAS PanDA Monitoring System

CERN Document Server

Schovancova, J; The ATLAS collaboration; Klimentov, A; Love, P; Potekhin, M; Wenaus, T

2014-01-01

For many years the PanDA Workload Management System has been the basis for distributed production and analysis for the ATLAS experiment at the LHC. Since the start of data taking PanDA usage has ramped up steadily, with up to 1M completed jobs/day in 2013. The associated monitoring data volume has been rising as well, to levels that present a new set of challenges in the areas of database scalability and monitoring system performance and efficiency. Outside of ATLAS, the PanDA system is also being used in projects like AMS, LSST and a few others. It currently undergoes a significant redesign, both of the core server components responsible for workload management, brokerage and data access, and of the monitoring part, which is critically important for efficient execution of the workflow in a way that’s transparent to the user and also provides an effective set of tools for operational support. The new generation of the PanDA Monitoring Service is designed based on a proven, scalable, industry-standard Web Fr...

PanDA Pilot Submission using Condor-G: Experience and Improvements

CERN Document Server

Zhao, Xin; The ATLAS collaboration; Wlodek, Tom; Wenaus, Torre; Frey, Jaime; Tannenbaum, Todd; Livny, Miron

2010-01-01

PanDA is the workload management system of the ATLAS experiment, used to run production and user analysis jobs on the grid. As a late-binding, pilot-based system, the maintenance of a smooth and steady stream of pilot jobs to all grid sites is critical for PanDA operation. The ATLAS Computing Facility (ACF) at BNL, as the ATLAS Tier 1 center in the US, operates the pilot submission systems for the US. This is done using the PanDA "AutoPilot" scheduler component which submits pilot jobs via Condor-G, a grid job scheduling system developed at the University of Wisconsin-Madison. In this talk, we discuss the operation and performance of the Condor-G pilot submission at BNL, with emphasis on the challenges and issues encountered in the real grid production environment. With the close collaboration of Condor and PanDA teams, the scalability and stability of the overall system has been greatly improved over the last year. We review improvements made to Condor-G resulting from this collaboration, including isolation...

PanDA Pilot Submission using Condor-G: Experience and Improvements

CERN Document Server

Zhao, X; The ATLAS collaboration; Wlodek, T; Wenaus, T; Frey, J; Tannenbaum, T; Livny, M

2011-01-01

PanDA (Production and Distributed Analysis) is the workload management system of the ATLAS experiment, used to run managed production and user analysis jobs on the grid. As a late-binding, pilot-based system, the maintenance of a smooth and steady stream of pilot jobs to all grid sites is critical for PanDA operation. The ATLAS Computing Facility (ACF) at BNL, as the ATLAS Tier1 center in the US, operates the pilot submission systems for the US. This is done using the PanDA “AutoPilot” scheduler component which submits pilot jobs via Condor-G, a grid job scheduling system developed at the University of Wisconsin-Madison. In this paper, we discuss the operation and performance of the Condor-G pilot submission at BNL, with emphasis on the challenges and issues encountered in the real grid production environment. With the close collaboration of Condor and PanDA teams, the scalability and stability of the overall system has been greatly improved over the last year. We review improvements made to Condor-G resu...

PANDAS: The Need to Use Definitive Diagnostic Criteria

Directory of Open Access Journals (Sweden)

Harvey S. Singer

2015-07-01

Full Text Available The entity Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections (PANDAS was initially proposed in 1998 (Swedo, et al. 1998. The formal diagnosis required that the affected individual meet five specific criteria: prepubertal onset, obsessive compulsive disorder (OCD and/or a tic disorder, the dramatic sudden explosive onset of symptoms, a relapsing and remitting course of symptoms that are temporally associated with Group A beta-hemolytic streptococcal (GABHS infection, and the presence of other neuropsychiatric abnormalities (hyperactivity, emotional lability, anxiety, or piano-playing choreiform movements. Since that original report, the PANDAS hypothesis has remained controversial based on both clinical grounds and the failure to confirm a definitive immune process.  This editorial was written in response to:Helm CE, Blackwood RA. Pediatric autoimmune neuropsychiatric disorder associated with streptococcal infections (PANDAS: Experience at a tertiary referral center. Tremor Other Hyperkinet Mov. 2015; 5. doi: 10.7916/D8348JCX 

PANDA: A Multipurpose Integral Test Facility for LWR Safety Investigations

International Nuclear Information System (INIS)

Paladino, D.; Dreier, J.

2012-01-01

The PANDA facility is a large scale, multicompartmental thermal hydraulic facility suited for investigations related to the safety of current and advanced LWRs. The facility is multipurpose, and the applications cover integral containment response tests, component tests, primary system tests, and separate effect tests. Experimental investigations carried on in the PANDA facility have been embedded in international projects, most of which under the auspices of the EU and OECD and with the support of a large number of organizations (regulatory bodies, technical dupport organizations, national laboratories, electric utilities, industries) worldwide. The paper provides an overview of the research programs performed in the PANDA facility in relation to BWR containment systems and those planned for PWR containment systems.

Extending the ATLAS PanDA Workload Management System for New Big Data Applications

CERN Document Server

De, K; The ATLAS collaboration; Maeno, T; Nilsson, P; Panitkin, S; Vaniachine, A; Wenaus, T; Yu, D

2013-01-01

The LHC experiments are today at the leading edge of large scale distributed data-intensive computational science. The LHC's ATLAS experiment processes data volumes which are particularly extreme, over 130 PB to date, distributed worldwide at over of 120 sites. An important element in the success of the exciting physics results from ATLAS is the highly scalable integrated workflow and dataflow management afforded by the PanDA workload management system, used for all the distributed computing needs of the experiment. The PanDA design is not experiment specific and PanDA is now being extended to support other data intensive scientific applications. Alpha-Magnetic Spectrometer, an astro-particle experiment on the International Space Station, and the Compact Muon Solenoid, an LHC experiment, have successfully evaluated PanDA and are pursuing its adoption. PanDA was cited as an example of "a high performance, fault tolerant software for fast, scalable access to data repositories of many kinds" during the "Big Data...

PanDA: Exascale Federation of Resources for the ATLAS Experiment at the LHC

Directory of Open Access Journals (Sweden)

Megino Fernando Barreiro

2016-01-01

The PanDA (Production and Distributed Analysis system was developed in 2005 for the ATLAS experiment on top of this heterogeneous infrastructure to seamlessly integrate the computational resources and give the users the feeling of a unique system. Since its origins, PanDA has evolved together with upcoming computing paradigms in and outside HEP, such as changes in the networking model, Cloud Computing and HPC. It is currently running steadily up to 200 thousand simultaneous cores (limited by the available resources for ATLAS, up to two million aggregated jobs per day and processes over an exabyte of data per year. The success of PanDA in ATLAS is triggering the widespread adoption and testing by other experiments. In this contribution we will give an overview of the PanDA components and focus on the new features and upcoming challenges that are relevant to the next decade of distributed computing workload management using PanDA.

PD2P : PanDA Dynamic Data Placement for ATLAS

CERN Multimedia

CERN. Geneva

2012-01-01

The PanDA Dynamic Data Placement (PD2P) system has been developed to cope with difficulties of data placement for ATLAS. PD2P is an intelligent subsystem of PanDA to distribute data by taking the following factors into account: popularity, locality, the usage pattern of the data, the distribution of CPU and storage resources, ...

Microbial diversity and evidence of novel homoacetogens in the gut of both geriatric and adult giant pandas (Ailuropoda melanoleuca.

Directory of Open Access Journals (Sweden)

Hein Min Tun

Full Text Available Recent studies have described the bacterial community residing in the guts of giant pandas, together with the presence of lignocellulolytic enzymes. However, a more comprehensive understanding of the intestinal microbial composition and its functional capacity in giant pandas remains a major goal. Here, we conducted a comparison of bacterial, fungal and homoacetogenic microbial communities from fecal samples taken from two geriatric and two adult captive giant pandas. 16S rDNA amplicon pyrosequencing revealed that Firmicutes and Proteobacteria are the most abundant microbiota in both geriatric and adult giant pandas. However, members of phylum Actinobacteria found in adult giant pandas were absent in their geriatric counterparts. Similarly, ITS1 amplicon pyrosequencing identified developmental changes in the most abundant fungal classes from Sordariomycetes in adult pandas to Saccharomycetes in geriatric pandas. Geriatric pandas exhibited significantly higher abundance of a potential probiotic fungus (Candida tropicalis as compared to adult pandas, indicating their importance in the normal digestive physiology of aged pandas. Our study also reported the presence of a lignocellulolytic white-rot fungus, Perenniporia medulla-panis, and the evidence of novel homoacetogens residing in the guts of giant pandas.

PanDA Pilot Submission using Condor-G: Experience and Improvements

International Nuclear Information System (INIS)

Zhao Xin; Hover, John; Wlodek, Tomasz; Wenaus, Torre; Frey, Jaime; Tannenbaum, Todd; Livny, Miron

2011-01-01

PanDA (Production and Distributed Analysis) is the workload management system of the ATLAS experiment, used to run managed production and user analysis jobs on the grid. As a late-binding, pilot-based system, the maintenance of a smooth and steady stream of pilot jobs to all grid sites is critical for PanDA operation. The ATLAS Computing Facility (ACF) at BNL, as the ATLAS Tier1 center in the US, operates the pilot submission systems for the US. This is done using the PanDA 'AutoPilot' scheduler component which submits pilot jobs via Condor-G, a grid job scheduling system developed at the University of Wisconsin-Madison. In this paper, we discuss the operation and performance of the Condor-G pilot submission at BNL, with emphasis on the challenges and issues encountered in the real grid production environment. With the close collaboration of Condor and PanDA teams, the scalability and stability of the overall system has been greatly improved over the last year. We review improvements made to Condor-G resulting from this collaboration, including isolation of site-based issues by running a separate Gridmanager for each remote site, introduction of the 'Nonessential' job attribute to allow Condor to optimize its behavior for the specific character of pilot jobs, better understanding and handling of the Gridmonitor process, as well as better scheduling in the PanDA pilot scheduler component. We will also cover the monitoring of the health of the system.

Factors affecting genotyping success in giant panda fecal samples

Directory of Open Access Journals (Sweden)

Ying Zhu

2017-05-01

Full Text Available Fecal samples play an important role in giant panda conservation studies. Optimal preservation conditions and choice of microsatellites for giant panda fecal samples have not been established. In this study, we evaluated the effect of four factors (namely, storage type (ethanol (EtOH, EtOH −20 °C, 2-step storage medium, DMSO/EDTA/Tris/salt buffer (DETs and frozen at −20 °C, storage time (one, three and six months, fragment length, and repeat motif of microsatellite loci on the success rate of microsatellite amplification, allelic dropout (ADO and false allele (FA rates from giant panda fecal samples. Amplification success and ADO rates differed between the storage types. Freezing was inferior to the other four storage methods based on the lowest average amplification success and the highest ADO rates (P < 0.05. The highest microsatellite amplification success was obtained from either EtOH or the 2-step storage medium at three storage time points. Storage time had a negative effect on the average amplification of microsatellites and samples stored in EtOH and the 2-step storage medium were more stable than the other three storage types. We only detected the effect of repeat motif on ADO and FA rates. The lower ADO and FA rates were obtained from tri- and tetra-nucleotide loci. We suggest that freezing should not be used for giant panda fecal preservation in microsatellite studies, and EtOH and the 2-step storage medium should be chosen on priority for long-term storage. We recommend candidate microsatellite loci with longer repeat motif to ensure greater genotyping success for giant panda fecal studies.

Modelling of particular phenomena observed in PANDA with Gothic

International Nuclear Information System (INIS)

Bandurski, Th.; Putz, F.; Andreani, M.; Analytis, M.

2000-01-01

PANDA is a large scale facility for investigating the long-term decay heat removal from the containment of a next generation 'passive' Advanced Light Water Reactor (ALWR). The first test series was aimed at the investigation of the long-term LOCA response of the Passive Containment Cooling System (PCCS) for the General Electric (GE) Simplified Boiling Water Reactor (SBWR). Recently, the facility is used in the framework of two European projects for investigating the performance of four passive cooling systems, i.e. the Building Condenser (BC) designed by Siemens for the SWR-1000 long-term containment cooling, the Passive Containment Cooling System for the European Simplified Boiling Water Reactor (ESBWR), the Containment Plate Condenser (CPC) and the Isolation Condenser (IC) for cooling of a BWR core. The PANDA tests have the dual objectives of improving confidence in the performance of the passive heat removal mechanisms underlying the design of the tested safety systems and extending the data base available for containment analysis code qualification. Among others, the containment analysis code Gothic was chosen for the analysis of particular phenomena observed during the PANDA tests. Ibis paper presents selected safety relevant phenomena observed in the PANDA tests and identified for the analyses and possible approaches for their modeling with Gothic. (author)

A novel polyomavirus from the nasal cavity of a giant panda (Ailuropoda melanoleuca).

Science.gov (United States)

Qi, Dunwu; Shan, Tongling; Liu, Zhijian; Deng, Xutao; Zhang, Zhihe; Bi, Wenlei; Owens, Jacob Robert; Feng, Feifei; Zheng, Lisong; Huang, Feng; Delwart, Eric; Hou, Rong; Zhang, Wen

2017-10-27

Polyomaviruses infect a wide variety of mammalian and avian hosts with a broad spectrum of outcomes including asymptomatic infection, acute systemic disease, and tumor induction. Viral metagenomics and general PCR methods were used to detected viral nucleic acid in the samples from a diseased and healthy giant pandas. A novel polyomavirus, the giant panda polyomavirus 1 (GPPyV1) from the nasal cavity of a dead giant panda (Ailuropoda melanoleuca) was characterized. The GPPyV1 genome is 5144 bp in size and reveals five putative open-reading frames coding for the classic small and large T antigens in the early region, and the VP1, VP2 and VP3 capsid proteins in the late region. Phylogenetic analyses of the large T antigen of the GPPyV1 indicated GPPyV1 belonged to a putative new species within genus Deltapolyomavirus, clustering with four human polyomavirus species. The GPPyV1 VP1 and VP2 clustered with genus Alphapolyomavirus. Our epidemiologic study indicated that this novel polyomavirus was also detected in nasal swabs and fecal samples collected from captive healthy giant pandas. A novel polyomavirus was detected in giant pandas and its complete genome was characterized, which may cause latency infection in giant pandas.

Giant pandas failed to show mirror self-recognition.

Science.gov (United States)

Ma, Xiaozan; Jin, Yuan; Luo, Bo; Zhang, Guiquan; Wei, Rongping; Liu, Dingzhen

2015-05-01

Mirror self-recognition (MSR), i.e., the ability to recognize oneself in a mirror, is considered a potential index of self-recognition and the foundation of individual development. A wealth of literature on MSR is available for social animals, such as chimpanzees, Asian elephants and dolphins, yet little is known about MSR in solitary mammalian species. We aimed to evaluate whether the giant panda can recognize itself in the mirror, and whether this capacity varies with age. Thirty-four captive giant pandas (F:M = 18:16; juveniles, sub-adults and adults) were subjected to four mirror tests: covered mirror tests, open mirror tests, water mark control tests, and mark tests. The results showed that, though adult, sub-adult and juvenile pandas exposed to mirrors spent similar amounts of time in social mirror-directed behaviors (χ(2) = 0.719, P = 0.698), none of them used the mirror to touch the mark on their head, a self-directed behavior suggesting MSR. Individuals of all age groups initially displayed attacking, threatening, foot scraping and backwards walking behaviors when exposed to their self-images in the mirror. Our data indicate that, regardless of age, the giant pandas did not recognize their self-image in the mirror, but instead considered the image to be a conspecific. Our results add to the available information on mirror self-recognition in large mammals, provide new information on a solitary species, and will be useful for enclosure design and captive animal management.

Development of a cluster-jet target for PANDA

International Nuclear Information System (INIS)

Gruber, A.; Marton, J.; Widmann, E.; Zmeskal, J.; Orth, H.; Luehning, J.

2008-01-01

Full text: The Stefan Meyer Institut (SMI) is part of the international PANDA collaboration. The universal detector will be constructed at the future high-energy antiproton storage ring HESR at FAIR (Facility for Antiproton and Ion Research, GSI/Darmstadt). PANDA will use antiproton beams (1.5 to 15 GeV/c) for hadron physics in the charmonium region. The physics program of PANDA will encompass charmonium spectroscopy below and above open charm threshold, search for exotics (glueballs, hybrids), lambda and double-lambda hypernuclei studies and the investigation of in-medium modifications of charmed mesons - an experimentally unexplored field. SMI contributes to major parts of the PANDA detector like the hydrogen cluster-jet target and the vacuum system of the antiproton - target interaction zone. In order to reach the desired target density, an optimization of the cold head, the nozzle and the skimmer arrangement is essential. A density-profile monitor for the cluster-jet was designed and built at SMI. Several nozzle types will be studied using different gases, temperatures and inlet pressures. Additionally we, together with the cluster-jet target group at GSI, are carrying out R and D for improving the jet-density. The Genova/Fermilab cluster-jet target used for these measurements has been in use at Fermilab for the experiments E760 and E835 and has been transferred to GSI for this purpose. The setup of the density-profile monitor at SMI and several measurements at GSI will be presented. (author)

Development of a cluster-jet target for PANDA

International Nuclear Information System (INIS)

Gruber, A.; Marton, J.; Widmann, E.; Zmeskal, J.; PANDA Cluster Jet Target Group

2006-01-01

Full text: The Stefan Meyer Institute (SMI) is part of the international PANDA collaboration. The universal detector will be constructed for the future high-energy antiproton storage ring HESR at FAIR (Facility for Antiproton and Ion Research, GSI/Darmstadt). PANDA will use antiproton beams (1.5 to 15 GeV/c) for hadron physics in the charmonium region. The physics program of PANDA will comprehend charmonium spectroscopy below and above open charm threshold, search for exotics (glueballs, hybrids), lambda and double-lambda hypernuclei studies and the investigation of in-medium modifications of charmed mesons - an experimentally unexplored field. SMI contributes to major parts of the PANDA detector like the hydrogen cluster-jet target and the antiproton - cluster jet interaction zone: in order to reach the desired target density, an optimization of the nozzle and the skimmer arrangement is essential. A density-profile monitor for the cluster-jet was designed and built at SMI. Several nozzle types have been studied using different gases, temperatures and inlet pressures. To ensure low background the residual gas load in the interaction zone has to be minimized. The installation of NEG (non-evaporative-getter) coated beam pipes is planned. A prototype of the interaction zone has been set up at SMI. The pumping capacity of NEG and the reactivation cycles were tested. The status of the development of the cluster-jet target and studies of the interaction region will be presented (author)

Low noise preamplifier ASIC for the PANDA experiment

International Nuclear Information System (INIS)

Flemming, H; Wieczorek, P

2011-01-01

For the electromagnetic calorimeter of the PANDA detector a preamplifier ASIC named APFEL (ASIC for Panda Front-end ELectronics) has been developed at GSI. It is optimized for the readout of large area avalanche photodiodes (LAAPDs) with a capacitance of 300 pF and an event rate of 350 kHz. The ASIC has two equivalent analog channels each consisting of a charge sensitive amplifier, a shaper stage and differential output drivers. For operating the ASIC in a wide temperature range programmable voltage references are implemented on chip.

Distribution and habitat use of red panda in the Chitwan-Annapurna Landscape of Nepal.

Science.gov (United States)

Bista, Damber; Shrestha, Saroj; Sherpa, Peema; Thapa, Gokarna Jung; Kokh, Manish; Lama, Sonam Tashi; Khanal, Kapil; Thapa, Arjun; Jnawali, Shant Raj

2017-01-01

In Nepal, the red panda (Ailurus fulgens) has been sparsely studied, although its range covers a wide area. The present study was carried out in the previously untapped Chitwan-Annapurna Landscape (CHAL) situated in central Nepal with an aim to explore current distributional status and identify key habitat use. Extensive field surveys conducted in 10 red panda range districts were used to estimate species distribution by presence-absence occupancy modeling and to predict distribution by presence-only modeling. The presence of red pandas was recorded in five districts: Rasuwa, Nuwakot, Myagdi, Baglung and Dhading. The predictive distribution model indicated that 1,904.44 km2 of potential red panda habitat is available in CHAL with the protected area covering nearly 41% of the total habitat. The habitat suitability analysis based on the probability of occurrence showed only 16.58% (A = 315.81 km2) of the total potential habitat is highly suitable. Red Panda occupancy was estimated to be around 0.0667, indicating nearly 7% (218 km2) of the total habitat is occupied with an average detection probability of 0.4482±0.377. Based on the habitat use analysis, altogether eight variables including elevation, slope, aspect, proximity to water sources, bamboo abundance, height, cover, and seasonal precipitation were observed to have significant roles in the distribution of red pandas. In addition, 25 tree species were documented from red panda sign plots out of 165 species recorded in the survey area. Most common was Betula utilis followed by Rhododendron spp. and Abies spectabilis. The extirpation of red pandas in previously reported areas indicates a need for immediate action for the long-term conservation of this species in CHAL.

Next generation PanDA pilot for ATLAS and other experiments

International Nuclear Information System (INIS)

Nilsson, P; De, K; Megino, F Barreiro; Llamas, R Medrano; Bejar, J Caballero; Hover, J; Maeno, T; Wenaus, T; Love, P; Walker, R

2014-01-01

The Production and Distributed Analysis system (PanDA) has been in use in the ATLAS Experiment since 2005. It uses a sophisticated pilot system to execute submitted jobs on the worker nodes. While originally designed for ATLAS, the PanDA Pilot has recently been refactored to facilitate use outside of ATLAS. Experiments are now handled as plug-ins such that a new PanDA Pilot user only has to implement a set of prototyped methods in the plug-in classes, and provide a script that configures and runs the experiment-specific payload. We will give an overview of the Next Generation PanDA Pilot system and will present major features and recent improvements including live user payload debugging, data access via the Federated XRootD system, stage-out to alternative storage elements, support for the new ATLAS DDM system (Rucio), and an improved integration with glExec, as well as a description of the experiment-specific plug-in classes. The performance of the pilot system in processing LHC data on the OSG, LCG and Nordugrid infrastructures used by ATLAS will also be presented. We will describe plans for future development on the time scale of the next few years.

Status of gastrointestinal parasites in Red Panda of Nepal.

Science.gov (United States)

Bista, Damber; Shrestha, Saroj; Kunwar, Ajaya Jang; Acharya, Sakshi; Jnawali, Shant Raj; Acharya, Krishna Prasad

2017-01-01

Red pandas are known to be highly susceptible to endoparasites, which can have a prominent impact on the population dynamics of this endangered species. There are very limited published reports on prevalence and risk of parasites in wild populations of red panda, especially localized reports. This study attempts to provide an in-depth insight of the status of endoparasites in red pandas, which is critical for strengthening conservation efforts. A total of 272 fecal samples were collected through systematic sampling across the red panda distribution range in Nepal and coprological examination was completed using standard techniques. It was followed by an estimation of prevalence and mean intensity of parasites, as well as statistical analysis, which was carried out using R statistical software. Parasite prevalence was documented in 90.80% ( n  = 247) out of 272 samples examined which includes seven different species along with three genera of parasites belonging to Protozoans (3 species), Cestodes (1 genus, 1 species) and Nematodes (2 genera, 3 species). Nematodes predominated in all infected samples (87.62%). Prevalence of Ancyclostoma duodenale ( n  = 227, 70.06%), having a mean intensity of 3.45 ± 2.88 individuals per sample, was observed, followed by Ascaris lumbricoides ( n  = 19, 5.86%) and Entamoeba histolytica ( n  = 24, 7.41%). Eight variables for assessing the determinants of infestation were tested: protected areas; non-protected areas; aspect; elevation; slope; and distance to water sources, herding stations, and settlements. Only the settlement displayed significant association ( β = -1534e-04, t  =  - 2.192, p  = 0.0293) though each parasite species displayed dissimilar association with different variables. This study indicates the urgent need of improving existing herding practice through habitat zonation, rotational grazing, medication of livestock, and prohibition of open defecation within and around red panda habitat.

Why does the giant panda eat bamboo? A comparative analysis of appetite-reward-related genes among mammals.

Directory of Open Access Journals (Sweden)

Ke Jin

Full Text Available BACKGROUND: The giant panda has an interesting bamboo diet unlike the other species in the order of Carnivora. The umami taste receptor gene T1R1 has been identified as a pseudogene during its genome sequencing project and confirmed using a different giant panda sample. The estimated mutation time for this gene is about 4.2 Myr. Such mutation coincided with the giant panda's dietary change and also reinforced its herbivorous life style. However, as this gene is preserved in herbivores such as cow and horse, we need to look for other reasons behind the giant panda's diet switch. METHODOLOGY/PRINCIPAL FINDINGS: Since taste is part of the reward properties of food related to its energy and nutrition contents, we did a systematic analysis on those genes involved in the appetite-reward system for the giant panda. We extracted the giant panda sequence information for those genes and compared with the human sequence first and then with seven other species including chimpanzee, mouse, rat, dog, cat, horse, and cow. Orthologs in panda were further analyzed based on the coding region, Kozak consensus sequence, and potential microRNA binding of those genes. CONCLUSIONS/SIGNIFICANCE: Our results revealed an interesting dopamine metabolic involvement in the panda's food choice. This finding suggests a new direction for molecular evolution studies behind the panda's dietary switch.

Simulation studies for the PANDA endcap disc DIRC

Energy Technology Data Exchange (ETDEWEB)

Schmidt, Mustafa; Biguenko, Klim; Dueren, Michael; Hayrapetyan, Avetik; Kroeck, Benno; Merle, Oliver; Rieke, Julian [II. Physikalisches Institut, Justus-Liebig-Universitaet, Giessen (Germany); Foehl, Klaus [CERN, Genf (Switzerland); Collaboration: PANDA-Collaboration

2015-07-01

The physics program of the PANDA detector at the future FAIR facility at GSI requires excellent particle identification. For the Panda forward endcap region a novel detector type called ''Disc DIRC'' has been designed. It covers the angular range between 5 and 22 degrees and uses internally reflected Cherenkov light in order to separate pions, kaons and protons up to a momentum of 4 GeV/c. During the design phase, extensive detector simulations have been performed to optimize and evaluate the design. The simulations were done using Geant4 and the PandaRoot framework in addition with a dedicated reconstruction software. An important aspect was the optimization of the imaging while taking the geometrical tolerances of the manufacturing process of the final detector into account. The main focus lies on the optimization process of the cylindrical and polynomial focussing optics at the edges of the detector plate, which has been performed with the merit function of a raytracer called PyOptics, written by one of the group members.

Simplified pilot module development and testing within the ATLAS PanDA Pilot 2.0 Project

CERN Document Server

Drizhuk, Daniil; The ATLAS collaboration; Nilsson, Paul

2016-01-01

The Production and Distributed Analysis (PanDA) system has been developed to meet ATLAS production and analysis requirements for a data-driven workload management system capable of operating at the LHC data processing scale. The PanDA pilot is one of the major components in the PanDA system. It runs on a worker node and takes care of setting up the environment, fetching and pushing data to storage, getting jobs from the PanDA server and executing them. The original PanDA Pilot was designed over 10 years ago and has since then grown organically. Large parts of the original pilot code base are now getting old and are difficult to maintain. Incremental changes and refactoring have been pushed to the limit, and the time is now right for a fresh start, informed by a decade of experience, with the PanDA Pilot 2.0 Project. To create a testing environment for module development and automated unit and functional testing for next generation pilot tasks, a simple pilot version was developed. It resembles the basic workf...

Genetic assessment of captive red panda (Ailurus fulgens) population.

Science.gov (United States)

Kumar, Arun; Rai, Upashna; Roka, Bhupen; Jha, Alankar K; Reddy, P Anuradha

2016-01-01

Red panda (Ailurus fulgens) is threatened across its range by detrimental human activities and rapid habitat changes necessitating captive breeding programs in various zoos globally to save this flagship species from extinction. One of the ultimate aims of ex situ conservation is reintroduction of endangered animals into their natural habitats while maintaining 90 % of the founder genetic diversity. Advances in molecular genetics and microsatellite genotyping techniques make it possible to accurately estimate genetic diversity of captive animals of unknown ancestry. Here we assess genetic diversity of the red panda population in Padmaja Naidu Himalayan Zoological Park, Darjeeling, which plays a pivotal role in ex situ conservation of red panda in India. We generated microsatellite genotypes of fifteen red pandas with a set of fourteen loci. This population is genetically diverse with 68 % observed heterozygosity (H O ) and mean inbreeding (F IS ) coefficient of 0.05. However population viability analysis reveals that this population has a very low survival probability (<2 %) and will rapidly loose its genetic diversity to 37 % mainly due to small population size and skewed male-biased sex ratio. Regular supplementation with a pair of adult individuals every five years will increase survival probability and genetic diversity to 99 and 61 % respectively and will also support future harvesting of individuals for reintroduction into the wild and exchange with other zoos.

The Panda Strip Asic: Pasta

Science.gov (United States)

Lai, A.

2018-01-01

PASTA is the 64 channel front-end chip, designed in a 110 nm CMOS technology to read out the strip sensors of the Micro Vertex Detector (MVD) of the PANDA experiment. This chip provides high resolution timestamp and deposited charge information by means of the time-over-threshold technique. Its working principle is based on a predecessor, the TOFPET ASIC, that was designed for medical applications. A general restructuring of the architecture was needed, in order to meet the specific requirements imposed by the physics programme of PANDA, especially in terms of radiation tolerance, spatial constraints, and readout in absence of a first level hardware trigger. The first revision of PASTA is currently under evaluation at the Forschungszentrum Jülich, where a data acquisition system dedicated to the MVD prototypes has been developed. This paper describes the main aspect of the chip design, gives an overview of the data acquisition system used for the verification, and shows the first results regarding the performance of PASTA.

Improving Security in the ATLAS PanDA System

International Nuclear Information System (INIS)

Caballero, J; Maeno, T; Potekhin, M; Wenaus, T; Nilsson, P; Stewart, G

2011-01-01

The security challenges faced by users of the grid are considerably different to those faced in previous environments. The adoption of pilot jobs systems by LHC experiments has mitigated many of the problems associated with the inhomogeneities found on the grid and has greatly improved job reliability; however, pilot jobs systems themselves must then address many security issues, including the execution of multiple users' code under a common 'grid' identity. In this paper we describe the improvements and evolution of the security model in the ATLAS PanDA (Production and Distributed Analysis) system. We describe the security in the PanDA server which is in place to ensure that only authorized members of the VO are allowed to submit work into the system and that jobs are properly audited and monitored. We discuss the security in place between the pilot code itself and the PanDA server, ensuring that only properly authenticated workload is delivered to the pilot for execution. When the code to be executed is from a 'normal' ATLAS user, as opposed to the production system or other privileged actor, then the pilot may use an EGEE developed identity switching tool called gLExec. This changes the grid proxy available to the job and also switches the UNIX user identity to protect the privileges of the pilot code proxy. We describe the problems in using this system and how they are overcome. Finally, we discuss security drills which have been run using PanDA and show how these improved our operational security procedures.

A new genotype of Cryptosporidium from giant panda (Ailuropoda melanoleuca) in China.

Science.gov (United States)

Liu, Xuehan; He, Tingmei; Zhong, Zhijun; Zhang, Hemin; Wang, Rongjun; Dong, Haiju; Wang, Chengdong; Li, Desheng; Deng, Jiabo; Peng, Guangneng; Zhang, Longxian

2013-10-01

Fifty-seven fecal samples were collected from giant pandas (Ailuropoda melanoleuca) in the China Conservation and Research Centre for the Giant Panda (CCRCGP) in Sichuan and examined for Cryptosporidium oocysts by Sheather's sugar flotation technique. An 18-year-old male giant panda was Cryptosporidium positive, with oocysts of an average size of 4.60×3.99 μm (n=50). The isolate was genetically analyzed using the partial 18S rRNA, 70 kDa heat shock protein (HSP70), Cryptosporidium oocyst wall protein (COWP) and actin genes. Multi-locus genetic characterization indicated that the present isolate was different from known Cryptosporidium species and genotypes. The closest relative was the Cryptosporidium bear genotype, with 11, 10, and 6 nucleotide differences in the 18S rRNA, HSP70, and actin genes, respectively. Significant differences were also observed in the COWP gene compared to Cryptosporidium mongoose genotype. The homology to the bear genotype at the 18S rRNA locus was 98.6%, which is comparable to that between Cryptosporidium parvum and Cryptosporidium hominis (99.2%), or between Cryptosporidium muris and Cryptosporidium andersoni (99.4%). Therefore, the Cryptosporidium in giant pandas in this study is considered as a new genotype: the Cryptosporidium giant panda genotype. © 2013 Elsevier Ireland Ltd. All rights reserved.

Integration Of PanDA Workload Management System With Supercomputers

CERN Document Server

Klimentov, Alexei; The ATLAS collaboration; Maeno, Tadashi; Mashinistov, Ruslan; Nilsson, Paul; Oleynik, Danila; Panitkin, Sergey; Read, Kenneth; Ryabinkin, Evgeny; Wenaus, Torre

2015-01-01

The Large Hadron Collider (LHC), operating at the international CERN Laboratory in Geneva, Switzerland, is leading Big Data driven scientific explorations. Experiments at the LHC explore the fundamental nature of matter and the basic forces that shape our universe, and were recently credited for the discovery of a Higgs boson. ATLAS, one of the largest collaborations ever assembled in the sciences, is at the forefront of research at the LHC. To address an unprecedented multi-petabyte data processing challenge, the ATLAS experiment is relying on a heterogeneous distributed computational infrastructure. The ATLAS experiment uses PanDA (Production and Data Analysis) Workload Management System for managing the workflow for all data processing on over 140 data centers. Through PanDA, ATLAS physicists see a single computing facility that enables rapid scientific breakthroughs for the experiment, even though the data centers are physically scattered all over the world. While PanDA currently uses more than 100,000 co...

Improvements for PanDA and intermediate layers

Energy Technology Data Exchange (ETDEWEB)

Kawamura, Gen; Magradze, Erekle; Musheghyan, Haykuhi; Nadal, Jordi; Quadt, Arnulf; Rzehorz, Gerhard [II. Physikalisches Institut, Georg-August-Universitaet Goettingen (Germany)

2015-07-01

The PanDA Production and Distributed Analysis system is handling the ATLAS workload management for production and distributed analysis processing. It was designed for analysis as well as production for High Energy Physics. One of the advantages of this pilot based system is, that it has its own integrated monitoring solution. Monitoring is a method used in computing, it means that a certain process is observed and overseen and is usually also protocolled. In the case of a process or system failure, a responsible person should be notified and countermeasures taken. Since PanDA is very versatile, it can also be used to process jobs on a computing Cloud, instead of just using the Grid(WLCG). Cloud computing resources can be provided by private companies, that bill the resources that are actually being used, for example CPU power over time. The advantage of this is obvious if one looks at the cost. They are basically the same, whether a huge task is done on little CPU power over a long time or on plenty of CPU power in a short time. For these reasons, a close monitoring, for example by the PanDA system for the usage of Cloud resources is important.

Estimation of the growth curve and heritability of the growth rate for giant panda (Ailuropoda melanoleuca) cubs.

Science.gov (United States)

Che, T D; Wang, C D; Jin, L; Wei, M; Wu, K; Zhang, Y H; Zhang, H M; Li, D S

2015-03-27

Giant panda cubs have a low survival rate during the newborn and early growth stages. However, the growth and developmental parameters of giant panda cubs during the early lactation stage (from birth to 6 months) are not well known. We examined the growth and development of giant panda cubs by the Chapman growth curve model and estimated the heritability of the maximum growth rate at the early lactation stage. We found that 83 giant panda cubs reached their maximum growth rate at approximately 75-120 days after birth. The body weight of cubs at 75 days was 4285.99 g. Furthermore, we estimated that the heritability of the maximum growth rate was moderate (h(2) = 0.38). Our study describes the growth and development of giant panda cubs at the early lactation stage and provides valuable growth benchmarks. We anticipate that our results will be a starting point for more detailed research on increasing the survival rate of giant panda cubs. Feeding programs for giant panda cubs need further improvement.

SINTESIS DE LA EVOLUCION HISTORICA DEL HOSPITAL SAN JUAN DE DIOS

Directory of Open Access Journals (Sweden)

Hernando Forero Caballero

1985-12-01

Full Text Available

La evolución del hospital de San Juan de Dios, como entidad de carácter asistencial para la salud del pueblo colombiano, se puede dividir en 5 etapas, correspondientes al progreso médico, histórico y cultural del país. La primera etapa, fetal o "de crisálida" como la llamó el Profesor López de Mesa, se inició en 1564 con la organización de la colonia española en Santafé y consistió en el establecimiento de una casa con unas camas destinadas a atender a los españoles que padecían alguna enfermedad, por circunstancias climáticas o infectados de bacterias importadas por ellos mismos. La atención médica, si tal puede llamarse, la ofrecían los monjes que, por intuición o por poseer alguna cultura generala mística religiosa, eran las únicas personas con ciertas condiciones para proporcionar algún alivio a los enfermos.

El hospital nació de la necesidad de proteger la salud de los conquistadores y sus familias y sobre todo del terror que les inspiraban las epidemias.

La evolución del hospital de San Juan de Dios, como entidad de carácter asistencial para la salud del pueblo colombiano, se puede dividir en 5 etapas, correspondientes al progreso médico, histórico y cultural del país. La primera etapa, fetal o "de crisálida" como la llamó el Profesor López de Mesa, se inició en 1564 con la organización de la colonia española en Santafé y consistió en el establecimiento de una casa con unas camas destinadas a atender a los españoles que padecían alguna enfermedad, por circunstancias climáticas o infectados de bacterias importadas por ellos mismos. La atención médica, si tal puede llamarse, la ofrecían los monjes que, por intuición o por poseer alguna cultura genera la mística religiosa, eran las únicas personas con ciertas condiciones para proporcionar algún alivio a los enfermos. El hospital nació de la necesidad de proteger la salud de los conquistadores y sus familias y sobre todo del terror

The appearance of 'Lambda' and 'Panda' sign on Ga-67 scintigraphy in sarcoidosis

International Nuclear Information System (INIS)

Yoshimizu, Tazuko; Suga, Kazuyoshi; Orihashi, Norihiro; Soejima, Kyoko; Kaneko, Takafumi; Kawamura, Mitsutoshi; Nakanishi, Takashi; Utsumi, Hiromoto; Yamada, Norimasa

1991-01-01

The lesions of sarcoidosis generally show relatively high Ga-67 uptake and the usefulness of scintigraphy using this agent in the evaluation of lesion activity is well known. In this report, we assessed characteristic uptake of Ga-67 in intrathoracic lymph nodes, the shape of which resembled the Greek letter Lambda (Lambda sign) and a symmetrical accumulation in bilateral lacrimal and salivary glands which resembled a Panda face (Panda sign) in patients with sarcoidosis. Our review of Ga-67 scans obtained from 15 patients with sarcoidosis and 1,779 patients with other disorders during the past 3 years revealed that the simultaneous presence of both Lambda and Panda signs was specific to patients with sarcoidosis and was not found in patients with various other disorders, although one of these signs might be observed in patients without sarcoidosis. When Lambda-like sign was observed, chest radiogram or CT was necessary for the differential diagnosis of sarcoidosis. Panda sign was observed frequently among patients who had previously received irradiation of the neck. Our results confirmed that sarcoidosis must be suspected when both Lambda and Panda signs were observed. (author)

Comparing the plant diversity between artificial forest and nature growth forest in a giant panda habitat.

Science.gov (United States)

Kang, Dongwei; Wang, Xiaorong; Li, Shuang; Li, Junqing

2017-06-15

Artificial restoration is an important way to restore forests, but little is known about its effect on the habitat restoration of the giant panda. In the present study, we investigated the characteristics of artificial forest in the Wanglang Nature Reserve to determine whether through succession it has formed a suitable habitat for the giant panda. We compared artificial forest characteristics with those of natural habitat used by the giant panda. We found that the dominant tree species in artificial forest differed from those in the natural habitat. The artificial forest had lower plant species richness and diversity in the tree and shrub layers than did the latter, and its community structure was characterized by smaller tree and bamboo sizes, and fewer and lower bamboo clumps, but more trees and larger shrub sizes. The typical community collocation of artificial forest was a "Picea asperata + no-bamboo" model, which differs starkly from the giant panda's natural habitat. After several years of restoration, the artificial forest has failed to become a suitable habitat for the giant panda. Therefore, a simple way of planting individual trees cannot restore giant panda habitat; instead, habitat restoration should be based on the habitat requirements of the giant panda.

Panda-Huggers and Dragon-Slayers: How to View Modern China Today

Science.gov (United States)

Gifford, Rob

2010-01-01

Panda-hugger and dragon-slayer are phrases used to describe two different kinds of China-watchers, and increasingly, two different types of people in the general public. A panda-hugger is someone who says that almost everything going on in China is good, that China's progress is a great thing for the world, and that any problems are peripheral. A…

Lyme disease and pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS: an overview

Directory of Open Access Journals (Sweden)

Rhee H

2012-02-01

Full Text Available Hanna Rhee1, Daniel J Cameron21Medicine, San Diego, CA, 2Northern Westchester Hospital, Mount Kisco, NY, USAAbstract: Lyme disease (LD is a complex, multisystemic illness. As the most common vector-borne disease in the United States, LD is caused by bacterial spirochete Borrelia burgdorferi sensu stricto, with potential coinfections from agents of anaplasmosis, babesiosis, and ehrlichiosis. Persistent symptoms and clinical signs reflect multiorgan involvement with episodes of active disease and periods of remission, not sparing the coveted central nervous system. The capability of microorganisms to cause and exacerbate various neuropsychiatric pathology is also seen in pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS, a recently described disorder attributed to bacterium Streptococcus pyogenes of group A beta-hemolytic streptococcus in which neurologic tics and obsessive-compulsive disorders are sequelae of the infection. In the current overview, LD and PANDAS are juxtaposed through a review of their respective infectious etiologies, clinical presentations, mechanisms of disease development, courses of illness, and treatment options. Future directions related to immunoneuropsychiatry are also discussed.Keywords: neuroborreliosis, infection, obsessive-compulsive disorder, tic disorder, Borrelia burgdorferi, strep throat

A genome-wide survey on basic helix-loop-helix transcription factors in giant panda.

Directory of Open Access Journals (Sweden)

Chunwang Dang

Full Text Available The giant panda (Ailuropoda melanoleuca is a critically endangered mammalian species. Studies on functions of regulatory proteins involved in developmental processes would facilitate understanding of specific behavior in giant panda. The basic helix-loop-helix (bHLH proteins play essential roles in a wide range of developmental processes in higher organisms. bHLH family members have been identified in over 20 organisms, including fruit fly, zebrafish, mouse and human. Our present study identified 107 bHLH family members being encoded in giant panda genome. Phylogenetic analyses revealed that they belong to 44 bHLH families with 46, 25, 15, 4, 11 and 3 members in group A, B, C, D, E and F, respectively, while the remaining 3 members were assigned into "orphan". Compared to mouse, the giant panda does not encode seven bHLH proteins namely Beta3a, Mesp2, Sclerax, S-Myc, Hes5 (or Hes6, EBF4 and Orphan 1. These results provide useful background information for future studies on structure and function of bHLH proteins in the regulation of giant panda development.

Cranial shape transformation in the evolution of the giant panda ( Ailuropoda melanoleuca)

Science.gov (United States)

Figueirido, Borja; Palmqvist, Paul; Pérez-Claros, Juan A.; Dong, Wei

2011-02-01

In this study, landmark-based methods of geometric morphometrics are used for investigating the main aspects of cranial shape transformation in the evolution of the giant panda, Ailuropoda melanoleuca. Specifically, we explore if the highly derived cranial adaptations for bamboo feeding of the living panda were developed early in the panda's lineage. Results obtained show that the overall cranial morphologies of the oldest known panda, the "pygmy" Ailuropoda microta, and the late Pleistocene Ailuropoda baconi are both very similar to that of their closest living relative, A. melanoleuca, which agrees with a previous proposal based on qualitative criteria. However, we also describe several differences between the crania of A. microta, A. baconi, and A. melanoleuca, including the development of the postorbital process, the orientation of the occipital region, and the expansion of the braincase. As a result, the cranial morphology of A. microta shows a less specialized morphology toward a fibrous and durophagous diet compared to the giant panda. These results are confirmed by a comparative analysis of the dimensions of the upper teeth in bears, which has revealed differences in relative tooth size between A. microta and A. melanoleuca, most probably as a result of mosaic evolution. Therefore, we conclude that cranial shape did not remain essentially uniform in the Ailuropoda lineage, as previously thought, but underwent a number of changes during more than 2 Myr.

Giant panda BAC library construction and assembly of a 650-kb contig spanning major histocompatibility complex class II region

Directory of Open Access Journals (Sweden)

Pan Hui-Juan

2007-09-01

Full Text Available Abstract Background Giant panda is rare and endangered species endemic to China. The low rates of reproductive success and infectious disease resistance have severely hampered the development of captive and wild populations of the giant panda. The major histocompatibility complex (MHC plays important roles in immune response and reproductive system such as mate choice and mother-fetus bio-compatibility. It is thus essential to understand genetic details of the giant panda MHC. Construction of a bacterial artificial chromosome (BAC library will provide a new tool for panda genome physical mapping and thus facilitate understanding of panda MHC genes. Results A giant panda BAC library consisting of 205,800 clones has been constructed. The average insert size was calculated to be 97 kb based on the examination of 174 randomly selected clones, indicating that the giant panda library contained 6.8-fold genome equivalents. Screening of the library with 16 giant panda PCR primer pairs revealed 6.4 positive clones per locus, in good agreement with an expected 6.8-fold genomic coverage of the library. Based on this BAC library, we constructed a contig map of the giant panda MHC class II region from BTNL2 to DAXX spanning about 650 kb by a three-step method: (1 PCR-based screening of the BAC library with primers from homologous MHC class II gene loci, end sequences and BAC clone shotgun sequences, (2 DNA sequencing validation of positive clones, and (3 restriction digest fingerprinting verification of inter-clone overlapping. Conclusion The identifications of genes and genomic regions of interest are greatly favored by the availability of this giant panda BAC library. The giant panda BAC library thus provides a useful platform for physical mapping, genome sequencing or complex analysis of targeted genomic regions. The 650 kb sequence-ready BAC contig map of the giant panda MHC class II region from BTNL2 to DAXX, verified by the three-step method, offers a

Characterizing the spatial distribution of giant pandas (Ailuropoda melanoleuca) in fragmented forest landscapes

NARCIS (Netherlands)

Wang, T.; Ye, X.P.; Skidmore, A.K.; Toxopeus, A.G.

2010-01-01

Aim. To examine the effects of forest fragmentation on the distribution of the entire wild giant panda (Ailuropoda melanoleuca) population, and to propose a modelling approach for monitoring the spatial distribution and habitat of pandas at the landscape scale using Moderate Resolution Imaging

Comparative morphology of the muscles of mastication in the giant panda and the Asiatic black bear.

Science.gov (United States)

Endo, Hideki; Taru, Hajime; Yamamoto, Masako; Arishima, Kazuyoshi; Sasaki, Motoki

2003-06-01

The morphological differences in the muscles of mastication between the giant panda (Ailuropoda melanoleuca) and the Asiatic black bear (Ursus thibetanus) were sought to confirm the adaptational strategy of these muscles in the giant panda. We measured some skull characteristics and weighed the muscles of mastication, and macroscopically observed the muscles of mastication in the two species. The noticeable differences between the two species are classified as follows: (1) The size ratio of the zygomatic width was much larger in the giant panda than in the Asiatic black bear. (2) The weight ratio of the two pterygoid muscles was also much larger in the giant panda than in the Asiatic black bear. (3) The lateral slips of the temporal muscles are thicker and stronger in the Asiatic black bear than in the giant panda. (4) The deep layer of the masseter muscle was rostrocaudally divided, and a complicated running of tendons is observed in the giant panda. (5) The two pterygoid muscles were much larger and well-developed in the giant panda than in the Asiatic black bear. The points (1) and (4) may be related to the generation of the force necessary to chew the bamboo in the giant panda. We thought that the large mass of the masseter and temporal muscles are needed in this species. In the points of (2) and (5), the two pterygoid muscles were obviously different in form and weight ratio between the two species. We suggest that the two pterygoid muscles may act as an additional force generator to dorsoventrally press and crush bamboo stems.

Serosurvey of infectious disease agents of carnivores in captive red pandas (Ailurus fulgens) in China.

Science.gov (United States)

Qin, Qin; Wei, Fuwen; Li, Ming; Dubovi, Edward J; Loeffler, I Kati

2007-03-01

The future of the endangered red panda (Ailurusfulgens) depends in part on the development of protective measures against infectious diseases. The present study is a first step toward improved understanding of infectious diseases in the species' home regions. Serum samples obtained from 73 red pandas in 10 captive facilities in southwest, east, and northeast China from October to December 2004 were tested for antibodies against nine common infectious pathogens of carnivores. Antibody titers against canine distemper virus (CDV), canine parvovirus (CPV), and canine adenovirus (CAV) in the three facilities in which red pandas were vaccinated were highly variable. The CAV titer in one vaccinated red panda was high enough to suggest infection with the field virus following vaccination. Together with anecdotal reports of vaccine-associated morbidity and mortality, our results suggest that the Chinese vaccine is not suitable for this species. In the seven unvaccinated groups, CDV titers were low and occurred in 20-100% of the animals; antibody titers against CPV were found in seven of eight areas. Only one of 61 and two of 61 unvaccinated red pandas had CAV and canine coronavirus titers, respectively, and these titers were all low. Positive titers to Toxoplasma gondii were found in four locations (33-94% seropositive); the titers in 52% of seropositive individuals were of a magnitude consistent with active disease in other species (1:1,024 to > or = 1:4,096). One red panda in each of three locations was seropositive for Neospora caninum. Antibodies against canine herpesvirus and Brucella canis were not detected in any of the samples. Only one of the 73 red pandas had a weak positive influenza A titer. The results of this study emphasize the need for research on and protection against infectious diseases of red pandas and other endangered species in China.

Population genetics of Enterocytozoon bieneusi in captive giant pandas of China.

Science.gov (United States)

Li, Wei; Song, Yuan; Zhong, Zhijun; Huang, Xiangming; Wang, Chengdong; Li, Caiwu; Yang, Haidi; Liu, Haifeng; Ren, Zhihua; Lan, Jingchao; Wu, Kongju; Peng, Guangneng

2017-10-18

Most studies on Enterocytozoon bieneusi are conducted based on the internal transcribed spacer (ITS) region of the rRNA gene, whereas some have examined E. bieneusi population structures. Currently, the population genetics of this pathogen in giant panda remains unknown. The objective of this study was to determine the E. bieneusi population in captive giant pandas in China. We examined 69 E. bieneusi-positive specimens from captive giant pandas in China using five loci (ITS, MS1, MS3, MS4 and MS7) to infer E. bieneusi population genetics. For multilocus genotype (MLG) analysis of E. bieneusi-positive isolates, the MS1, MS3, MS4, and MS7 microsatellite and minisatellite loci were amplified and sequenced in 48, 45, 50 and 47 specimens, respectively, generating ten, eight, nine and five types. We successfully amplified 36 specimens and sequenced all five loci, forming 24 MLGs. Multilocus sequence analysis revealed a strong and significant linkage disequilibrium (LD), indicating a clonal population. This result was further supported by measurements of pairwise intergenic LD and a standardized index of association (I S A ) from allelic profile data. The analysis in STRUCTURE suggested three subpopulations in E. bieneusi, further confirmed using right's fixation index (F ST ). Subpopulations 1 and 2 exhibited an epidemic structure, whereas subpopulation 3 had a clonal structure. Our results describe E. bieneusi population genetics in giant pandas for the first time, improving the current understanding E. bieneusi epidemiology in the studied region. These data also benefit future studies exploring potential transmission risks from pandas to other animals, including humans.

Kretzoiarctos gen. nov., the oldest member of the giant panda clade.

Science.gov (United States)

Abella, Juan; Alba, David M; Robles, Josep M; Valenciano, Alberto; Rotgers, Cheyenn; Carmona, Raül; Montoya, Plinio; Morales, Jorge

2012-01-01

The phylogenetic position of the giant panda, Ailuropoda melanoleuca (Carnivora: Ursidae: Ailuropodinae), has been one of the most hotly debated topics by mammalian biologists and paleontologists during the last century. Based on molecular data, it is currently recognized as a true ursid, sister-taxon of the remaining extant bears, from which it would have diverged by the Early Miocene. However, from a paleobiogeographic and chronological perspective, the origin of the giant panda lineage has remained elusive due to the scarcity of the available Miocene fossil record. Until recently, the genus Ailurarctos from the Late Miocene of China (ca. 8-7 mya) was recognized as the oldest undoubted member of the Ailuropodinae, suggesting that the panda lineage might have originated from an Ursavus ancestor. The role of the purported ailuropodine Agriarctos, from the Miocene of Europe, in the origins of this clade has been generally dismissed due to the paucity of the available material. Here, we describe a new ailuropodine genus, Kretzoiarctos gen. nov., based on remains from two Middle Miocene (ca. 12-11 Ma) Spanish localities. A cladistic analysis of fossil and extant members of the Ursoidea confirms the inclusion of the new genus into the Ailuropodinae. Moreover, Kretzoiarctos precedes in time the previously-known, Late Miocene members of the giant panda clade from Eurasia (Agriarctos and Ailurarctos). The former can be therefore considered the oldest recorded member of the giant panda lineage, which has significant implications for understanding the origins of this clade from a paleobiogeographic viewpoint.

Kretzoiarctos gen. nov., the oldest member of the giant panda clade.

Directory of Open Access Journals (Sweden)

Juan Abella

Full Text Available The phylogenetic position of the giant panda, Ailuropoda melanoleuca (Carnivora: Ursidae: Ailuropodinae, has been one of the most hotly debated topics by mammalian biologists and paleontologists during the last century. Based on molecular data, it is currently recognized as a true ursid, sister-taxon of the remaining extant bears, from which it would have diverged by the Early Miocene. However, from a paleobiogeographic and chronological perspective, the origin of the giant panda lineage has remained elusive due to the scarcity of the available Miocene fossil record. Until recently, the genus Ailurarctos from the Late Miocene of China (ca. 8-7 mya was recognized as the oldest undoubted member of the Ailuropodinae, suggesting that the panda lineage might have originated from an Ursavus ancestor. The role of the purported ailuropodine Agriarctos, from the Miocene of Europe, in the origins of this clade has been generally dismissed due to the paucity of the available material. Here, we describe a new ailuropodine genus, Kretzoiarctos gen. nov., based on remains from two Middle Miocene (ca. 12-11 Ma Spanish localities. A cladistic analysis of fossil and extant members of the Ursoidea confirms the inclusion of the new genus into the Ailuropodinae. Moreover, Kretzoiarctos precedes in time the previously-known, Late Miocene members of the giant panda clade from Eurasia (Agriarctos and Ailurarctos. The former can be therefore considered the oldest recorded member of the giant panda lineage, which has significant implications for understanding the origins of this clade from a paleobiogeographic viewpoint.

PAN-DA and beyond: Data acquisition for the next generation experiments

International Nuclear Information System (INIS)

Pordes, R.; Anderson, J.; Berg, D.; Berman, E.; Brown, D.; Dorries, T.; Mackinnon, B.; Meadows, J.; Moore, C.; Nicinski, T.; Oleynik, G.; Petravick, D.; Rechenmacher, R.; Sergey, G.; Slimmer, D.; Streets, J.; Vittone, M.; Votava, M.; Wilcer, N.; White, V.

1991-06-01

We report on the status of the PAN-DA data acquisition system presented at the last Real Time Conference. Since that time, PAN-DA has been successfully used in the fixed target program at Fermilab. We also report on the plans and strategies for development of a new data acquisition system for the next generation of fixed target experiments at Fermilab. 10 refs., 3 figs

Evaluating landscape options for corridor restoration between giant panda reserves.

Directory of Open Access Journals (Sweden)

Fang Wang

Full Text Available The establishment of corridors can offset the negative effects of habitat fragmentation by connecting isolated habitat patches. However, the practical value of corridor planning is minimal if corridor identification is not based on reliable quantitative information about species-environment relationships. An example of this need for quantitative information is planning for giant panda conservation. Although the species has been the focus of intense conservation efforts for decades, most corridor projects remain hypothetical due to the lack of reliable quantitative researches at an appropriate spatial scale. In this paper, we evaluated a framework for giant panda forest corridor planning. We linked our field survey data with satellite imagery, and conducted species occupancy modelling to examine the habitat use of giant panda within the potential corridor area. We then conducted least-cost and circuit models to identify potential paths of dispersal across the landscape, and compared the predicted cost under current conditions and alternative conservation management options considered during corridor planning. We found that due to giant panda's association with areas of low elevation and flat terrain, human infrastructures in the same area have resulted in corridor fragmentation. We then identified areas with high potential to function as movement corridors, and our analysis of alternative conservation scenarios showed that both forest/bamboo restoration and automobile tunnel construction would significantly improve the effectiveness of corridor, while residence relocation would not significantly improve corridor effectiveness in comparison with the current condition. The framework has general value in any conservation activities that anticipate improving habitat connectivity in human modified landscapes. Specifically, our study suggested that, in this landscape, automobile tunnels are the best means to remove current barriers to giant panda

TEPSS related PANDA tests (ESBWR)

International Nuclear Information System (INIS)

Huggenberger, M.; Aubert, C.; Bandurski, T.; Dreier, J.; Fischer, O.; Strassberger, H.J.; Yadigaroglu, G.

2000-01-01

A number of test series to investigate passive safety systems for the next generation of Light Water Reactors have been performed in the PANDA facility at the Paul Scherrer Institute (PSI). The large scale thermalhydraulic test facility allows to investigate Passive Containment Cooling Systems (PCCS) and the long-term containment behaviour after a Loss of Coolant Accident (LOCA). After successful completion of the ALPHA phase-I test series, where the PCCS performance of the Simplified Boiling Water Reactor (SBWR) was examined, phase-II was initiated in 1996 with new projects, all with international participation (EC Fourth Framework Programme on Nuclear Fission Safety). One of these projects is entitled 'Technology Enhancement for Passive Safety Systems' (TEPSS). TEPSS is focused on the European Simplified Boiling Water Reactor (ESBWR). Several new containment features and PCCS long-term response under different LOCA scenarios were investigated in PANDA. The PCCS start-up was demonstrated under challenging conditions. The effect of nitrogen hidden somewhere in the drywell and released later in the transient was simulated by injecting air for a certain period into the drywell. The effect of light gases on the PCCS performance was investigated by helium injection to the drywell. Finally, the influence of low PCC pool levels on PCCS and containment performance was examined. The main findings were that the PCCS works as intended and shows generally a favourable and robust long-term post LOCA behaviour. The system starts working even under extreme conditions and trapped air released from the drywell later in the transient does only temporarily reduce the PCCS performance. The new PANDA test series provided an extensive data base which will contribute to further improve containment design of passive plants and allow for system code assessment in a wide parameter range. (author)

The Endcap Disc DIRC of PANDA

Science.gov (United States)

Düren, M.; Etzelmüller, E.; Föhl, K.; Hayrapetyan, A.; Kröck, B.; Merle, O.; Rieke, J.; Schmidt, M.; Wasem, T.; Britting, A.; Eyrich, W.; Lehmann, A.; Pfaffinger, M.; Uhlig, F.; Belias, A.; Dzhygadlo, R.; Gerhardt, A.; Götzen, K.; Kalicy, G.; Krebs, M.; Lehmann, D.; Nerling, F.; Patsyuk, M.; Peters, K.; Schepers, G.; Schmitt, L.; Schwarz, C.; Schwiening, J.; Traxler, M.; Zühlsdorf, M.; Cowie, E.; Keri, T.; Achenbach, P.; Cardinali, M.; Hoek, M.; Lauth, W.; Schlimme, S.; Sfienti, C.; Thiel, M.

2017-12-01

The Endcap Disc DIRC (EDD) for PANDA has been designed to identify traversing pions, kaons and protons in the future PANDA experiment. Its central part is a 2 cm thick fused silica plate. Focussing optics are attached to the outer rim of the plate, outside of the acceptance of the experiment. Fast, high-resolution MCP-PMTs, designed to register single Cherenkov photons, have been tested in magnetic field. Filters limit the spectral acceptance of the sensors to reduce dispersion effects and to extend their lifetime. A compact and fast readout is realized with ASICs. Analytical reconstruction algorithms allow for fast particle identification. The angular resolution of a DIRC prototype has been simulated in Monte Carlo and confirmed in a test beam. The final detector will be able to provide a 4 σπ / K separation up to a momentum of 4 GeV / c .

Integration of PanDA workload management system with Titan supercomputer at OLCF

Science.gov (United States)

De, K.; Klimentov, A.; Oleynik, D.; Panitkin, S.; Petrosyan, A.; Schovancova, J.; Vaniachine, A.; Wenaus, T.

2015-12-01

The PanDA (Production and Distributed Analysis) workload management system (WMS) was developed to meet the scale and complexity of LHC distributed computing for the ATLAS experiment. While PanDA currently distributes jobs to more than 100,000 cores at well over 100 Grid sites, the future LHC data taking runs will require more resources than Grid computing can possibly provide. To alleviate these challenges, ATLAS is engaged in an ambitious program to expand the current computing model to include additional resources such as the opportunistic use of supercomputers. We will describe a project aimed at integration of PanDA WMS with Titan supercomputer at Oak Ridge Leadership Computing Facility (OLCF). The current approach utilizes a modified PanDA pilot framework for job submission to Titan's batch queues and local data management, with light-weight MPI wrappers to run single threaded workloads in parallel on Titan's multicore worker nodes. It also gives PanDA new capability to collect, in real time, information about unused worker nodes on Titan, which allows precise definition of the size and duration of jobs submitted to Titan according to available free resources. This capability significantly reduces PanDA job wait time while improving Titan's utilization efficiency. This implementation was tested with a variety of Monte-Carlo workloads on Titan and is being tested on several other supercomputing platforms. Notice: This manuscript has been authored, by employees of Brookhaven Science Associates, LLC under Contract No. DE-AC02-98CH10886 with the U.S. Department of Energy. The publisher by accepting the manuscript for publication acknowledges that the United States Government retains a non-exclusive, paid-up, irrevocable, world-wide license to publish or reproduce the published form of this manuscript, or allow others to do so, for United States Government purposes.

The PANDA detector at FAIR

International Nuclear Information System (INIS)

Bersani, Andrea

2012-01-01

The PANDA detector will be installed at FAIR to enterprise a long-term, wide-spectrum physics program in the strong interaction framework. The detector will be installed at the HESR accumulation ring, which will provide an anti-proton beam of unprecedented luminosity and momentum definition. The beam will interact with an internal target. The detector has been designed to allow a 4π coverage around the interaction region. Due to the relatively high energy of the beam, up to 15 GeV, PANDA will feature two magnetic spectrometers: the target spectrometer (TS), with a superconducting solenoid and covering the interaction region, and a forward spectrometer (FS), with a normal-conducting dipole and covering the small angles region. Since the physics program is wide and the requirements on the various subsystems are different, the detector has been designed to be as flexible as possible. The complete detector will be described in detail, both from the viewpoint of the proposed techniques and from the viewpoint of the expected performances. An overview of the status of various components of the detector will be presented, too.

The PANDA detector at FAIR

Science.gov (United States)

Bersani, Andrea

2012-10-01

The PANDA detector will be installed at FAIR to enterprise a long-term, wide-spectrum physics program in the strong interaction framework. The detector will be installed at the HESR accumulation ring, which will provide an anti-proton beam of unprecedented luminosity and momentum definition. The beam will interact with an internal target. The detector has been designed to allow a 4π coverage around the interaction region. Due to the relatively high energy of the beam, up to 15 GeV, PANDA will feature two magnetic spectrometers: the target spectrometer (TS), with a superconducting solenoid and covering the interaction region, and a forward spectrometer (FS), with a normal-conducting dipole and covering the small angles region. Since the physics program is wide and the requirements on the various subsystems are different, the detector has been designed to be as flexible as possible. The complete detector will be described in detail, both from the viewpoint of the proposed techniques and from the viewpoint of the expected performances. An overview of the status of various components of the detector will be presented, too.

Multi-strangeness dynamics at PANDA

Energy Technology Data Exchange (ETDEWEB)

Gaitanos, Theodoros; Lenske, Horst; Mosel, Ulrich [Institut fuer Theoretische Physik, Universitaet Giessen (Germany)

2014-07-01

Multi-strange bound hadron systems are excellent candidates for studying in-medium hyperon-hyperon (YY) interactions. A better understanding of the strangeness sector of the hadronic equation of state is crucial for our understanding of astrophysical objects like neutron stars. Furthermore, these studies are being motivated by actual and planed experimental activities on hypernuclear physics (HypHI and PANDA Collaborations). In fact, HypHI has already studied single-strange hypernuclei in heavy-ion collisions, whereas studies on double- and multi-strange nuclear systems are being planed by PANDA. We have reported in the past first studies on single- and double-Λ hypernuclei production in reactions induced by heavy-ions and antiprotons, respectively. The YY-interaction is still little known and many controversial theoretical predictions exist in the literature. We therefore extend our previous works by investigating the influence of various hyperon-hyperon interactions on the production dynamics of multi-Λ hypernuclei in reactions relevant for FAIR. Particular attention is paid to the heavy Ω-baryon (S=-3) and its role to the formation of multi-Λ hypernuclei in reactions induced by antiprotons.

The next generation PanDA Pilot for and beyond the ATLAS experiment

CERN Document Server

Nilsson, Paul; The ATLAS collaboration

2018-01-01

The Production and Distributed Analysis system (PanDA) is a pilot-based workload management system that was originally designed for the ATLAS Experiment at the LHC to operate on grid sites. Since the coming LHC data taking runs will require more resources than grid computing alone can provide, the various LHC experiments are engaged in an ambitious program to extend the computing model to include opportunistically used resources such as High Performance Computers (HPCs), clouds and volunteer computers. To this end, PanDA is being extended beyond grids and ATLAS to be used on the new types of resources as well as by other experiments. A new key component is being developed, the next generation PanDA Pilot (Pilot 2). Pilot 2 is a complete rewrite of the original PanDA Pilot which has been used in the ATLAS Experiment for over a decade. The new Pilot architecture follows a component-based approach which improves system flexibility, enables a clear workflow control, evolves the system according to modern function...

PanDA Beyond ATLAS : A Scalable Workload Management System For Data Intensive Science

CERN Document Server

Borodin, M; The ATLAS collaboration; Jha, S; Golubkov, D; Klimentov, A; Maeno, T; Nilsson, P; Oleynik, D; Panitkin, S; Petrosyan, A; Schovancova, J; Vaniachine, A; Wenaus, T

2014-01-01

The LHC experiments are today at the leading edge of large scale distributed data-intensive computational science. The LHC's ATLAS experiment processes data volumes which are particularly extreme, over 140 PB to date, distributed worldwide at over of 120 sites. An important element in the success of the exciting physics results from ATLAS is the highly scalable integrated workflow and dataflow management afforded by the PanDA workload management system, used for all the distributed computing needs of the experiment. The PanDA design is not experiment specific and PanDA is now being extended to support other data intensive scientific applications. PanDA was cited as an example of "a high performance, fault tolerant software for fast, scalable access to data repositories of many kinds" during the "Big Data Research and Development Initiative" announcement, a 200 million USD U.S. government investment in tools to handle huge volumes of digital data needed to spur science and engineering discoveries. In this talk...

Procesos operativos y satisfacción del usuario en radiodiagnóstico del hospital Sergio e. Bernales2015

OpenAIRE

Carbonel Arribasplata, José Antonio; Leiva López, Miryan Milagros

2016-01-01

La presente investigación trata sobre la relación entre los procesos operativos de gestión y su relación con la satisfacción del usuario ambulatorio en el servicio de Radiodiagnóstico durante el mes de Junio del 2015, en el servicio de radiodiagnóstico del hospital nacional Sergio E. Bernales, del distrito de Comas en la ciudad de Lima – Perú. Para el presente estudio de los procesos operativos de gestión nos hemos basado en los conceptos de I. Gonzales, que detalla en su li...

ESBWR related passive decay heat removal tests in PANDA

International Nuclear Information System (INIS)

Huggenberger, M.; Aubert, C.; Bandurski, T.; Dreier, J.; Fischer, O.; Strassberger, H.J.; Yadigaroglu, G.

1999-01-01

A number of test series to investigate passive safety systems for the next generation of Light Water Reactors have been performed in the PANDA multi-purpose facility at the Paul Scherrer Institut (PSI). The large scale thermal-hydraulic test facility allows to investigate LWR containment phenomena and system behaviour. PANDA was first used to examine the Passive Containment Cooling System (PCCS) for the Simplified Boiling Water Reactor (SBWR). In 1996 new test series were initiated; all related to projects of the EC Fourth Framework Programme on Nuclear Fission Safety. One of these projects (TEPSS) is focused on the European Simplified Boiling Water Reactor (ESBWR). The ESBWR containment features and PCCS long-term post LOCA response were investigated in PANDA. The PCCS start-up was demonstrated, the effect of nitrogen hidden somewhere in the drywell and released later in the transient was simulated and the effect of light gases (helium) on the PCCS performance was investigated. Finally, the influence of low PCC pool levels on PCCS and containment performance was examined. The main findings were that the PCCS works as intended and shows generally a favorable and robust long-term post LOCA behaviour. The system starts working even under extreme conditions and trapped air released from the drywell later in the transient does only temporarily reduce the PCCS performance. The new PANDA test series provided an extensive data base which will contribute to further improve containment design of passive plants and allow for system code assessment in a wide parameter range. (author)

PanDA for ATLAS Distributed Computing in the Next Decade

CERN Document Server

Barreiro Megino, Fernando Harald; The ATLAS collaboration

2016-01-01

The Production and Distributed Analysis (PanDA) system has been developed to meet ATLAS production and analysis requirements for a data-driven workload management system capable of operating at the Large Hadron Collider (LHC) data processing scale. Heterogeneous resources used by the ATLAS experiment are distributed worldwide at hundreds of sites, thousands of physicists analyse the data remotely, the volume of processed data is beyond the exabyte scale, dozens of scientific applications are supported, while data processing requires more than a few billion hours of computing usage per year. PanDA performed very well over the last decade including the LHC Run 1 data taking period. However, it was decided to upgrade the whole system concurrently with the LHC’s first long shutdown in order to cope with rapidly changing computing infrastructure. After two years of reengineering efforts, PanDA has embedded capabilities for fully dynamic and flexible workload management. The static batch job paradigm was discarde...

PanDA for ATLAS distributed computing in the next decade

CERN Document Server

AUTHOR|(SzGeCERN)643806; The ATLAS collaboration; De, Kaushik; Klimentov, Alexei; Maeno, Tadashi; Nilsson, Paul; Oleynik, Danila; Padolski, Siarhei; Panitkin, Sergey; Wenaus, Torre

2017-01-01

The Production and Distributed Analysis (PanDA) system has been developed to meet ATLAS production and analysis requirements for a data-driven workload management system capable of operating at the Large Hadron Collider (LHC) data processing scale. Heterogeneous resources used by the ATLAS experiment are distributed worldwide at hundreds of sites, thousands of physicists analyse the data remotely, the volume of processed data is beyond the exabyte scale, dozens of scientific applications are supported, while data processing requires more than a few billion hours of computing usage per year. PanDA performed very well over the last decade including the LHC Run 1 data taking period. However, it was decided to upgrade the whole system concurrently with the LHC’s first long shutdown in order to cope with rapidly changing computing infrastructure. After two years of reengineering efforts, PanDA has embedded capabilities for fully dynamic and flexible workload management. The static batch job paradigm was discarde...

PANDA a multi-purpose thermal-hydraulics facility devoted to nuclear reactor containment safety analysis

International Nuclear Information System (INIS)

Paladino, Domenico

2014-01-01

This paper presents the multi purpose facility PANDA devised for the safety analysis of nuclear reactor containment. The passive safety systems for LWRs have been explained with details about the PAssive Nachzerfallswärmeabfuhr und Druck-Abbau Testanlage (PANDA)

PANDA : Strong Interaction Studies with Antiprotons

NARCIS (Netherlands)

Peters, Klaus; Schmitt, Lars; Stockmanns, Tobias; Messchendorp, Johan

2017-01-01

The Antiproton Anihilation in Darmstadt (PANDA) collaboration at the Facility for Antiproton and Ion Research (FAIR) is a cooperation of more than 400 scientists from 19 countries. FAIR will be an accelerator facility leading the European research in nuclear and hadron physics in the coming decade.

The PANDA DIRC detectors at FAIR

Science.gov (United States)

Schwarz, C.; Ali, A.; Belias, A.; Dzhygadlo, R.; Gerhardt, A.; Götzen, K.; Kalicy, G.; Krebs, M.; Lehmann, D.; Nerling, F.; Patsyuk, M.; Peters, K.; Schepers, G.; Schmitt, L.; Schwiening, J.; Traxler, M.; Zühlsdorf, M.; Böhm, M.; Britting, A.; Eyrich, W.; Lehmann, A.; Pfaffinger, M.; Uhlig, F.; Düren, M.; Etzelmüller, E.; Föhl, K.; Hayrapetyan, A.; Kreutzfeld, K.; Kröck, B.; Merle, O.; Rieke, J.; Schmidt, M.; Wasem, T.; Achenbach, P.; Cardinali, M.; Hoek, M.; Lauth, W.; Schlimme, S.; Sfienti, C.; Thiel, M.; Allison, L.; Hyde, C.

2017-07-01

The PANDA detector at the international accelerator Facility for Antiproton and Ion Research in Europe (FAIR) addresses fundamental questions of hadron physics. An excellent hadronic particle identification (PID) will be accomplished by two DIRC (Detection of Internally Reflected Cherenkov light) counters in the target spectrometer. The design for the barrel region covering polar angles between 22o to 140o is based on the successful BABAR DIRC with several key improvements, such as fast photon timing and a compact imaging region. The novel Endcap Disc DIRC will cover the smaller forward angles between 5o (10o) to 22o in the vertical (horizontal) direction. Both DIRC counters will use lifetime-enhanced microchannel plate PMTs for photon detection in combination with fast readout electronics. Geant4 simulations and tests with several prototypes at various beam facilities have been used to evaluate the designs and validate the expected PID performance of both PANDA DIRC counters.

Evolution of the ATLAS PanDA Production and Distributed Analysis System

International Nuclear Information System (INIS)

Maeno, T; Wenaus, T; Fine, V; Potekhin, M; Panitkin, S; De, K; Nilsson, P; Stradling, A; Walker, R; Compostella, G

2012-01-01

The PanDA (Production and Distributed Analysis) system has been developed to meet ATLAS production and analysis requirements for a data-driven workload management system capable of operating at LHC data processing scale. PanDA has performed well with high reliability and robustness during the two years of LHC data-taking, while being actively evolved to meet the rapidly changing requirements for analysis use cases. We will present an overview of system evolution including automatic rebrokerage and reattempt for analysis jobs, adaptation for the CernVM File System, support for the multi-cloud model through which Tier-2 sites act as members of multiple clouds, pledged resource management and preferential brokerage, and monitoring improvements. We will also describe results from the analysis of two years of PanDA usage statistics, current issues, and plans for the future.

ATLAS WORLD-cloud and networking in PanDA

Science.gov (United States)

Barreiro Megino, F.; De, K.; Di Girolamo, A.; Maeno, T.; Walker, R.; ATLAS Collaboration

2017-10-01

The ATLAS computing model was originally designed as static clouds (usually national or geographical groupings of sites) around the Tier 1 centres, which confined tasks and most of the data traffic. Since those early days, the sites’ network bandwidth has increased at 0(1000) and the difference in functionalities between Tier 1s and Tier 2s has reduced. After years of manual, intermediate solutions, we have now ramped up to full usage of World-cloud, the latest step in the PanDA Workload Management System to increase resource utilization on the ATLAS Grid, for all workflows (MC production, data (re)processing, etc.). We have based the development on two new site concepts. Nuclei sites are the Tier 1s and large Tier 2s, where tasks will be assigned and the output aggregated, and satellites are the sites that will execute the jobs and send the output to their nucleus. PanDA dynamically pairs nuclei and satellite sites for each task based on the input data availability, capability matching, site load and network connectivity. This contribution will introduce the conceptual changes for World-cloud, the development necessary in PanDA, an insight into the network model and the first half-year of operational experience.

Metagenomic Study Suggests That the Gut Microbiota of the Giant Panda (Ailuropoda melanoleuca May Not Be Specialized for Fiber Fermentation

Directory of Open Access Journals (Sweden)

Wei Guo

2018-02-01

Full Text Available Bamboo-eating giant panda (Ailuropoda melanoleuca is an enigmatic species, which possesses a carnivore-like short and simple gastrointestinal tract (GIT. Despite the remarkable studies on giant panda, its diet adaptability status continues to be a matter of debate. To resolve this puzzle, we investigated the functional potential of the giant panda gut microbiome using shotgun metagenomic sequencing of fecal samples. We also compared our data with similar data from other animal species representing herbivores, carnivores, and omnivores from current and earlier studies. We found that the giant panda hosts a bear-like gut microbiota distinct from those of herbivores indicated by the metabolic potential of the microbiome in the gut of giant pandas and other mammals. Furthermore, the relative abundance of genes involved in cellulose- and hemicellulose-digestion, and enrichment of enzymes associated with pathways of amino acid degradation and biosynthetic reactions in giant pandas echoed a carnivore-like microbiome. Most significantly, the enzyme assay of the giant panda's feces indicated the lowest cellulase and xylanase activity among major herbivores, shown by an in-vitro experimental assay of enzyme activity for cellulose and hemicellulose-degradation. All of our results consistently indicate that the giant panda is not specialized to digest cellulose and hemicellulose from its bamboo diet, making the giant panda a good mammalian model to study the unusual link between the gut microbiome and diet. The increased food intake of the giant pandas might be a strategy to compensate for the gut microbiome functions, highlighting a strong need of conservation of the native bamboo forest both in high- and low-altitude ranges to meet the great demand of bamboo diet of giant pandas.

Metagenomic Study Suggests That the Gut Microbiota of the Giant Panda (Ailuropoda melanoleuca) May Not Be Specialized for Fiber Fermentation.

Science.gov (United States)

Guo, Wei; Mishra, Sudhanshu; Zhao, Jiangchao; Tang, Jingsi; Zeng, Bo; Kong, Fanli; Ning, Ruihong; Li, Miao; Zhang, Hengzhi; Zeng, Yutian; Tian, Yuanliangzi; Zhong, Yihang; Luo, Hongdi; Liu, Yunhan; Yang, Jiandong; Yang, Mingyao; Zhang, Mingwang; Li, Yan; Ni, Qingyong; Li, Caiwu; Wang, Chengdong; Li, Desheng; Zhang, Hemin; Zuo, Zhili; Li, Ying

2018-01-01

Bamboo-eating giant panda ( Ailuropoda melanoleuca ) is an enigmatic species, which possesses a carnivore-like short and simple gastrointestinal tract (GIT). Despite the remarkable studies on giant panda, its diet adaptability status continues to be a matter of debate. To resolve this puzzle, we investigated the functional potential of the giant panda gut microbiome using shotgun metagenomic sequencing of fecal samples. We also compared our data with similar data from other animal species representing herbivores, carnivores, and omnivores from current and earlier studies. We found that the giant panda hosts a bear-like gut microbiota distinct from those of herbivores indicated by the metabolic potential of the microbiome in the gut of giant pandas and other mammals. Furthermore, the relative abundance of genes involved in cellulose- and hemicellulose-digestion, and enrichment of enzymes associated with pathways of amino acid degradation and biosynthetic reactions in giant pandas echoed a carnivore-like microbiome. Most significantly, the enzyme assay of the giant panda's feces indicated the lowest cellulase and xylanase activity among major herbivores, shown by an in-vitro experimental assay of enzyme activity for cellulose and hemicellulose-degradation. All of our results consistently indicate that the giant panda is not specialized to digest cellulose and hemicellulose from its bamboo diet, making the giant panda a good mammalian model to study the unusual link between the gut microbiome and diet. The increased food intake of the giant pandas might be a strategy to compensate for the gut microbiome functions, highlighting a strong need of conservation of the native bamboo forest both in high- and low-altitude ranges to meet the great demand of bamboo diet of giant pandas.

Over Expression of Long Non-Coding RNA PANDA Promotes Hepatocellular Carcinoma by Inhibiting Senescence Associated Inflammatory Factor IL8.

Science.gov (United States)

Peng, Chuanhui; Hu, Wendi; Weng, Xiaoyu; Tong, Rongliang; Cheng, Shaobing; Ding, Chaofeng; Xiao, Heng; Lv, Zhen; Xie, Haiyang; Zhou, Lin; Wu, Jian; Zheng, Shusen

2017-06-23

It has been reported that long non-coding RNA PANDA was disregulated in varieties types of tumor, but its expression level and biological role in hepatocellular carcinoma (HCC) remains contradictory. We detected PANDA expression in two independent cohorts (48 HCC patients following liver transplantation and 84 HCC patients following liver resection), and found that PANDA was down-regulated in HCC. Thereafter we explored its function in cancer biology by inversing its low expression. Surprisingly, overexpression of PANDA promoted HCC proliferation and carcinogenesis in vitro and in vivo. Mechanistically, PANDA repressed transcriptional activity of senescence associated inflammatory factor IL8, which leaded to inhibition of cellular senescence. Therefore, our research help to better understand the complex role of PANDA in HCC, and suggest more thoughtful strategies should be applied before it can be treated as a potential therapeutic target.

The bamboo-eating giant panda harbors a carnivore-like gut microbiota, with excessive seasonal variations.

Science.gov (United States)

Xue, Zhengsheng; Zhang, Wenping; Wang, Linghua; Hou, Rong; Zhang, Menghui; Fei, Lisong; Zhang, Xiaojun; Huang, He; Bridgewater, Laura C; Jiang, Yi; Jiang, Chenglin; Zhao, Liping; Pang, Xiaoyan; Zhang, Zhihe

2015-05-19

The giant panda evolved from omnivorous bears. It lives on a bamboo-dominated diet at present, but it still retains a typical carnivorous digestive system and is genetically deficient in cellulose-digesting enzymes. To find out whether this endangered mammalian species, like other herbivores, has successfully developed a gut microbiota adapted to its fiber-rich diet, we conducted a 16S rRNA gene-based large-scale structural profiling of the giant panda fecal microbiota. Forty-five captive individuals were sampled in spring, summer, and late autumn within 1 year. Significant intraindividual variations in the diversity and structure of gut microbiota across seasons were observed in this population, which were even greater than the variations between individuals. Compared with published data sets involving 124 gut microbiota profiles from 54 mammalian species, these giant pandas, together with 9 captive and 7 wild individuals investigated previously, showed extremely low gut microbiota diversity and an overall structure that diverged from those of nonpanda herbivores but converged with those of carnivorous and omnivorous bears. The giant panda did not harbor putative cellulose-degrading phylotypes such as Ruminococcaceae and Bacteroides bacteria that are typically enriched in other herbivores, but instead, its microbiota was dominated by Escherichia/Shigella and Streptococcus bacteria. Members of the class Clostridia were common and abundant in the giant panda gut microbiota, but most of the members present were absent in other herbivores and were not phylogenetically related with known cellulolytic lineages. Therefore, the giant panda appears not to have evolved a gut microbiota compatible with its newly adopted diet, which may adversely influence the coevolutionary fitness of this herbivore. The giant panda, an endangered mammalian species endemic to western China, is well known for its unique bamboo diet. Unlike other herbivores that have successfully evolved

La arquitectura del pleno barroco en Granada: el hospital del Corpus Christi

Directory of Open Access Journals (Sweden)

Barrios Rozúa, Juan Manuel

2011-03-01

Full Text Available The Corpus Christi hospital of Granada was a victim of prejudices against the baroque on the part of influential historians. Nevertheless, the building is an interesting example of hospital architecture with a frankly original temple. Thanks to the exhaustive analysis of the institution’s very complete archive, it can be determined that some thirty artists worked there, including Alonso Cano and his disciple Juan Luis de Ortega, whose architectural works are evaluated here.

El hospital del Corpus Christi de Granada fue víctima de los prejuicios contra el barroco de influyentes historiadores. Sin embargo, el edificio constituye un interesante ejemplo de arquitectura hospitalaria con un templo francamente original. Gracias al análisis exhaustivo de su completo archivo, puede detectarse la labor de una treintena de artífices, entre ellos Alonso Cano y su discípulo Juan Luis de Ortega, cuyas obras arquitectónicas son valoradas aquí.

Repercusión del Clima Organizacional en la Calidad de Atención del Cliente Externo del Hospital I Samuel Pastor - Camaná. Arequipa, 2011

OpenAIRE

Cano Vargas, Ana María

2017-01-01

El objetivo de la presente tesis es determinar la repercusión del Clima Organizacional en la Calidad de Atención del Cliente Externo del Hospital I Camaná, teniendo en cuenta la satisfacción de las necesidades de salud de sus usuarios con eficiencia y eficacia. El nivel del estudio fue explicativo y la técnica e instrumento que se utilizaron para medir el Clima Organizacional y la Calidad de Atención fueron el cuestionario y la cédula de preguntas, respectivamente. En el Personal Profesion...

Preliminary Characterization of the Liquid Discharge of the Mexico Hospital; Caracterizacion Preliminar de la Descarga Liquida del Hospital Mexico

Energy Technology Data Exchange (ETDEWEB)

Hernandez Rojas, A

2001-07-01

constituye un grave problema a nivel nacional. En este trabajo se realiza una caracterizacion preliminar de la descarga liquida del Hospital Mexico. Para ello se analizaron diferentes puntos de vertido dentro de la institucion, ellos son : Lavanderia, cocina central, Laboratorio Clinico, Rayos X, Laboratorio de Biomasa, Morgue y la descarga final del hospital. Esto con el fin de conocer el manejo de los desechos liquidos en el centro de salud, la calidad sanitaria de estos vertidos y su influencia en las aguas crudas del Hospital Mexico en el cuerpo receptor. Para este estudio primero se coordino con el personal de cada departamento para conocer sobre el manejo y tipo de residuos liquidos que son descargados al sistema de tuberias. Posteriormente se realizaron las pruebas fisico-quimicas y biologicas con base en dos muestreos compuestos realizados los dias 26 de octubre y 4 de noviembre de 1998. Entre las pruebas realizadas se tienen: pH, DBO, DQO, SAAM, Grasas y Aceites, Temperatura, Nitrogeno y Coliformes Fecales, dependiendo de las caracteristicas de su punto de procedencia. Al final del estudio, se evaluaron los resultados obtenidos para cada punto de vertido estudiado y luego se analizo la influencia de estos focos sobre la calidad de las aguas crudas del hospital, las cuales descargan en una quebrada localizada al costado noroeste de las instalaciones. Los resultados obtenidos permiten conocer preliminarmente la caracterizacion de la descarga liquida del Hospital Mexico y lo catalogan como una fuente de contaminacion. El Hospital requiere de una planta de tratamiento biologica para aquellos vertidos biodegradables, y de un sistema de tratamiento quimico para tratar ese tipo de productos, que son utilizados en los procesos propios de cada departamento; ademas se requiere tomar en cuenta medidas de reduccion de contaminacion que disminuyan la cantidad de desechos desde la fuente. (Author)

The PANDA detector and its physics program at FAIR

International Nuclear Information System (INIS)

Brinkmann, K.

2005-01-01

The PANDA detector will make use of the antiprotons produced in the FAIR complex and stored in the High-Energy Storage Ring HESR for the study of strong interactions in antiproton collisions with protons and heavy targets. The detector features a 4π design for charged particles with a solenoidal magnetic field and full coverage of photons by means of an advanced electromagnetic calorimeter. In addition, a dipole spectrometer will allow high-resolution detection of leading particles characteristic for fixed-target experiments. The physics program of PANDA covers a wide range of topics which address central issues of QCD at low and moderate energies. Spectroscopy of hidden charm in the ccbar level scheme is still a very interesting issue, in particular when states are involved which cannot directly be formed in e + e - reactions. Open charm in the D meson section has recently received renewed interest when states were discovered that are not easily explained in conventional qqbar models. Exotic hadrons and glueballs have been predicted by theory within the energy range covered by PANDA. The search for these and the eventual study of their properties is central to the physics program. Using heavy targets, PANDA intends to study the properties of charm quarks in the hadronic medium. The copious production of baryon-antibaryon pairs at HESR will allow studies using secondary targets for the formation of hypernuclei. Each of these physics topics will be touched while the detector properties needed in order to cover the broad physics program are described. Technical developments and the status of the various detector components will be summarized

SWR 1000 related containment cooling system tests in PANDA

International Nuclear Information System (INIS)

Dreier, J.; Aubert, C.; Huggenberger, M.; Strassberger, H.J.; Yadigaroglu, G.

2000-01-01

Since 1991 the Paul Scherrer Institute has participated in the investigations of several of the new passive Advanced Light Water Reactor designs proposed world-wide. The current phase of the project, ALPHA-II, is focused on both the boiling water and the pressurized water reactor passive designs and consists of three projects under the sponsorship of the European Commission. The paper describes the performed PANDA transient system tests related to one of these projects, called 'BWR R and D Cluster for Innovative Passive Safety Systems (IPSS)', and details the PSI contribution to the experimental investigation of passive containment cooling by a Building Condenser system which is part of the advanced Boiling Water Reactor SWR 1000 designed by Siemens. First, a short description of the relevant systems of the SWR 1000 design and its simulation in the PANDA facility are presented. After the description of the experimental programme for the large-scale integral system test investigations in the PANDA facility, the main results of the performed tests are also given. Finally, the main conclusions, based on the to date available experimental results and their analysis, are summarised. (author)

The sequence and de novo assembly of the giant panda genome

Science.gov (United States)

Li, Ruiqiang; Fan, Wei; Tian, Geng; Zhu, Hongmei; He, Lin; Cai, Jing; Huang, Quanfei; Cai, Qingle; Li, Bo; Bai, Yinqi; Zhang, Zhihe; Zhang, Yaping; Wang, Wen; Li, Jun; Wei, Fuwen; Li, Heng; Jian, Min; Li, Jianwen; Zhang, Zhaolei; Nielsen, Rasmus; Li, Dawei; Gu, Wanjun; Yang, Zhentao; Xuan, Zhaoling; Ryder, Oliver A.; Leung, Frederick Chi-Ching; Zhou, Yan; Cao, Jianjun; Sun, Xiao; Fu, Yonggui; Fang, Xiaodong; Guo, Xiaosen; Wang, Bo; Hou, Rong; Shen, Fujun; Mu, Bo; Ni, Peixiang; Lin, Runmao; Qian, Wubin; Wang, Guodong; Yu, Chang; Nie, Wenhui; Wang, Jinhuan; Wu, Zhigang; Liang, Huiqing; Min, Jiumeng; Wu, Qi; Cheng, Shifeng; Ruan, Jue; Wang, Mingwei; Shi, Zhongbin; Wen, Ming; Liu, Binghang; Ren, Xiaoli; Zheng, Huisong; Dong, Dong; Cook, Kathleen; Shan, Gao; Zhang, Hao; Kosiol, Carolin; Xie, Xueying; Lu, Zuhong; Zheng, Hancheng; Li, Yingrui; Steiner, Cynthia C.; Lam, Tommy Tsan-Yuk; Lin, Siyuan; Zhang, Qinghui; Li, Guoqing; Tian, Jing; Gong, Timing; Liu, Hongde; Zhang, Dejin; Fang, Lin; Ye, Chen; Zhang, Juanbin; Hu, Wenbo; Xu, Anlong; Ren, Yuanyuan; Zhang, Guojie; Bruford, Michael W.; Li, Qibin; Ma, Lijia; Guo, Yiran; An, Na; Hu, Yujie; Zheng, Yang; Shi, Yongyong; Li, Zhiqiang; Liu, Qing; Chen, Yanling; Zhao, Jing; Qu, Ning; Zhao, Shancen; Tian, Feng; Wang, Xiaoling; Wang, Haiyin; Xu, Lizhi; Liu, Xiao; Vinar, Tomas; Wang, Yajun; Lam, Tak-Wah; Yiu, Siu-Ming; Liu, Shiping; Zhang, Hemin; Li, Desheng; Huang, Yan; Wang, Xia; Yang, Guohua; Jiang, Zhi; Wang, Junyi; Qin, Nan; Li, Li; Li, Jingxiang; Bolund, Lars; Kristiansen, Karsten; Wong, Gane Ka-Shu; Olson, Maynard; Zhang, Xiuqing; Li, Songgang; Yang, Huanming; Wang, Jian; Wang, Jun

2013-01-01

Using next-generation sequencing technology alone, we have successfully generated and assembled a draft sequence of the giant panda genome. The assembled contigs (2.25 gigabases (Gb)) cover approximately 94% of the whole genome, and the remaining gaps (0.05 Gb) seem to contain carnivore-specific repeats and tandem repeats. Comparisons with the dog and human showed that the panda genome has a lower divergence rate. The assessment of panda genes potentially underlying some of its unique traits indicated that its bamboo diet might be more dependent on its gut microbiome than its own genetic composition. We also identified more than 2.7 million heterozygous single nucleotide polymorphisms in the diploid genome. Our data and analyses provide a foundation for promoting mammalian genetic research, and demonstrate the feasibility for using next-generation sequencing technologies for accurate, cost-effective and rapid de novo assembly of large eukaryotic genomes. PMID:20010809

Evidence for lignin oxidation by the giant panda fecal microbiome.

Directory of Open Access Journals (Sweden)

Wei Fang

Full Text Available The digestion of lignin and lignin-related phenolic compounds from bamboo by giant pandas has puzzled scientists because of the lack of lignin-degrading genes in the genome of the bamboo-feeding animals. We constructed a 16S rRNA gene library from the microorganisms derived from the giant panda feces to identify the possibility for the presence of potential lignin-degrading bacteria. Phylogenetic analysis showed that the phylotypes of the intestinal bacteria were affiliated with the phyla Proteobacteria (53% and Firmicutes (47%. Two phylotypes were affiliated with the known lignin-degrading bacterium Pseudomonas putida and the mangrove forest bacteria. To test the hypothesis that microbes in the giant panda gut help degrade lignin, a metagenomic library of the intestinal bacteria was constructed and screened for clones that contained genes encoding laccase, a lignin-degrading related enzyme. A multicopper oxidase gene, designated as lac51, was identified from a metagenomic clone. Sequence analysis and copper content determination indicated that Lac51 is a laccase rather than a metallo-oxidase and may work outside its original host cell because it has a TAT-type signal peptide and a transmembrane segment at its N-terminus. Lac51 oxidizes a variety of lignin-related phenolic compounds, including syringaldazine, 2,6-dimethoxyphenol, ferulic acid, veratryl alcohol, guaiacol, and sinapinic acid at conditions that simulate the physiologic environment in giant panda intestines. Furthermore, in the presence of 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid (ABTS, syringic acid, or ferulic acid as mediators, the oxidative ability of Lac51 on lignin was promoted. The absorbance of lignin at 445 nm decreased to 36% for ABTS, 51% for syringic acid, and 51% for ferulic acid after incubation for 10 h. Our findings demonstrate that the intestinal bacteria of giant pandas may facilitate the oxidation of lignin moieties, thereby clarifying the digestion

Testbeam results of the PANDA endcap disc dirc

Energy Technology Data Exchange (ETDEWEB)

Etzelmueller, Erik; Biguenko, Klim; Dueren, Michael; Hayrapetyan, Avetik; Rieke, Julian; Schmidt, Mustafa [II. Physikalisches Institut, Justus-Liebig-Universitaet, Giessen (Germany); Collaboration: PANDA-Collaboration

2016-07-01

The physics program of the PANDA detector at the future FAIR facility at GSI requires excellent particle identification. For the PANDA forward endcap region a novel detector type called ''Disc DIRC'' has been designed. It covers the angular range between 5 and 22 degrees and uses internally reflected Cherenkov light in order to separate pions, kaons and protons up to a momentum of 4 GeV/c. A new prototype was tested at the PS East Area at CERN in May 2015. For the first time all optical components consisted of fused silica and different MCP-PMT sensors were used for the photon detection. A summary of the analysis will be presented along with results from in-house tests for the individual components.

Superconducting shielding for a polarized target in PANDA

Energy Technology Data Exchange (ETDEWEB)

Mora Espi, Maria Carmen; Froehlich, Bertold; Dbeyssi, Alaa; Aguar Bartolome, Patricia; Gerz, Kathrin; Ahmed, Samer; Wang, Yadi; Lin, Dexu; Feldbauer, Florian [Helmholtz-Institut Mainz (Germany); Penuelas, Ana [Universitat de Valencia (Spain); Collaboration: PANDA-Collaboration

2016-07-01

The measurement of the phase between the electric and the magnetic form factors of the proton can be measured using a polarized interaction. A feasible possibility to allow this kind of reactions would be to develop a transversely polarized proton target to be used in the PANDA experiment. The first step to achieve the transverse target polarization is to study the feasibility of shielding the target region from the external 2 T longitudinal magnetic field generated by the PANDA solenoid. BSCOO-2212, a new high-temperature superconductor material, has been identified as a possible candidate to be used for shielding this external magnetic field. Tests at 4 K have taken place in the Helmholtz Institute Mainz with this material, and the first preliminary results are shown here.

Perfil clínico del adulto mayor atendido ambulatoriamente en un hospital general.

OpenAIRE

Casas, Paola; Varela, Luis; Tello, Tania; Ortiz, Pedro; Chávez, Helver

2012-01-01

Objetivo: Describir el perfil clínico del adulto mayor atendido ambulatoriamente en un hospital general. Material y métodos: Estudio descriptivo, transversal, realizado a través de encuestas aplicadas a pacientes en la consulta ambulatoria de geriatría del Hospital Nacional Cayetano Heredia (HNCH), entre agosto de 2011 y enero 2012. Resultados: Se evaluaron 290 pacientes, el 69,3% fueron mujeres; el 65,5% tenía entre 60 y 79 años. La hipertensión arterial fue el diagnóstico más frecuente (55,...

NIVEL DE SATISFACCIÓN DEL PACIENTE ADULTO POSTOPERADO RESPECTO AL CUIDADO DE ENFERMERÍA EN SERVICIO DE CIRUGÌA DEL HOSPITAL REGIONAL DE LAMBAYEQUE

OpenAIRE

Oliva Ramos, Pamela; Universidad Señor de Sipán

2014-01-01

 El presente estudio Nivel de Satisfacción del Paciente Adulto Postoperado Respecto al Cuidado de Enfermería en Servicio de Cirugía del Hospital Regional de Lambayeque Chiclayo 2013, tuvo como objetivo: Determinar el nivel de satisfacción en el paciente adulto postoperado respecto al cuidado de enfermería en servicio de cirugía del Hospital Regional de Lambayeque Chiclayo 2013. El diseño metodológico fue de tipo cuantitativo descriptivo simple, se utilizó como instrumento el cuestionario tipo...

Profile of microRNA in Giant Panda Blood: A Resource for Immune-Related and Novel microRNAs.

Directory of Open Access Journals (Sweden)

Mingyu Yang

Full Text Available The giant panda (Ailuropoda melanoleuca is one of the world's most beloved endangered mammals. Although the draft genome of this species had been assembled, little was known about the composition of its microRNAs (miRNAs or their functional profiles. Recent studies demonstrated that changes in the expression of miRNAs are associated with immunity. In this study, miRNAs were extracted from the blood of four healthy giant pandas and sequenced by Illumina next generation sequencing technology. As determined by miRNA screening, a total of 276 conserved miRNAs and 51 novel putative miRNAs candidates were detected. After differential expression analysis, we noticed that the expressions of 7 miRNAs were significantly up-regulated in young giant pandas compared with that of adults. Moreover, 2 miRNAs were up-regulated in female giant pandas and 1 in the male individuals. Target gene prediction suggested that the miRNAs of giant panda might be relevant to the expressions of 4,602 downstream genes. Subseuqently, the predicted target genes were conducted to KEGG (Kyoto Encyclopedia of Genes and Genomes pathway analysis and we found that these genes were mainly involved in host immunity, including the Ras signaling pathway, the PI3K-Akt signaling pathway, and the MAPK signaling pathway. In conclusion, our results provide the first miRNA profiles of giant panda blood, and the predicted functional analyses may open an avenue for further study of giant panda immunity.

Profile of microRNA in Giant Panda Blood: A Resource for Immune-Related and Novel microRNAs.

Science.gov (United States)

Yang, Mingyu; Du, Lianming; Li, Wujiao; Shen, Fujun; Fan, Zhenxin; Jian, Zuoyi; Hou, Rong; Shen, Yongmei; Yue, Bisong; Zhang, Xiuyue

2015-01-01

The giant panda (Ailuropoda melanoleuca) is one of the world's most beloved endangered mammals. Although the draft genome of this species had been assembled, little was known about the composition of its microRNAs (miRNAs) or their functional profiles. Recent studies demonstrated that changes in the expression of miRNAs are associated with immunity. In this study, miRNAs were extracted from the blood of four healthy giant pandas and sequenced by Illumina next generation sequencing technology. As determined by miRNA screening, a total of 276 conserved miRNAs and 51 novel putative miRNAs candidates were detected. After differential expression analysis, we noticed that the expressions of 7 miRNAs were significantly up-regulated in young giant pandas compared with that of adults. Moreover, 2 miRNAs were up-regulated in female giant pandas and 1 in the male individuals. Target gene prediction suggested that the miRNAs of giant panda might be relevant to the expressions of 4,602 downstream genes. Subseuqently, the predicted target genes were conducted to KEGG (Kyoto Encyclopedia of Genes and Genomes) pathway analysis and we found that these genes were mainly involved in host immunity, including the Ras signaling pathway, the PI3K-Akt signaling pathway, and the MAPK signaling pathway. In conclusion, our results provide the first miRNA profiles of giant panda blood, and the predicted functional analyses may open an avenue for further study of giant panda immunity.

PanDA: Exascale Federation of Resources for the ATLAS Experiment at the LHC

Science.gov (United States)

Barreiro Megino, Fernando; Caballero Bejar, Jose; De, Kaushik; Hover, John; Klimentov, Alexei; Maeno, Tadashi; Nilsson, Paul; Oleynik, Danila; Padolski, Siarhei; Panitkin, Sergey; Petrosyan, Artem; Wenaus, Torre

2016-02-01

After a scheduled maintenance and upgrade period, the world's largest and most powerful machine - the Large Hadron Collider(LHC) - is about to enter its second run at unprecedented energies. In order to exploit the scientific potential of the machine, the experiments at the LHC face computational challenges with enormous data volumes that need to be analysed by thousand of physics users and compared to simulated data. Given diverse funding constraints, the computational resources for the LHC have been deployed in a worldwide mesh of data centres, connected to each other through Grid technologies. The PanDA (Production and Distributed Analysis) system was developed in 2005 for the ATLAS experiment on top of this heterogeneous infrastructure to seamlessly integrate the computational resources and give the users the feeling of a unique system. Since its origins, PanDA has evolved together with upcoming computing paradigms in and outside HEP, such as changes in the networking model, Cloud Computing and HPC. It is currently running steadily up to 200 thousand simultaneous cores (limited by the available resources for ATLAS), up to two million aggregated jobs per day and processes over an exabyte of data per year. The success of PanDA in ATLAS is triggering the widespread adoption and testing by other experiments. In this contribution we will give an overview of the PanDA components and focus on the new features and upcoming challenges that are relevant to the next decade of distributed computing workload management using PanDA.

Specialized consultant in radiological safety to the Ciudad del Carmen general hospital, PEMEX; Asesoria especializada en seguridad radiologica al hospital general Ciudad del Carmen, PEMEX

Energy Technology Data Exchange (ETDEWEB)

Angeles C, A.; Hernandez C, J. E.; Rodriguez A, F.; Garcia A, J

2003-02-15

The Ciudad del Carmen general hospital, dependent of PEMEX, It request consultant of the ININ to be able to maintain their sanitary license for the use of X-ray equipment for the radiologic diagnostic.The proposal of the ININ was to be a program of technical attendance, schedule monthly to be able to solve the observations that are presented in the use of those equipment, and that the hospital can conserve its respective sanitary license.(Author)

gLExec Integration with the ATLAS PanDA Workload Management System

CERN Document Server

Karavakis, Edward; Campana, Simone; De, Kaushik; Di Girolamo, Alessandro; Litmaath, Maarten; Maeno, Tadashi; Medrano Llamas, Ramon; Nilsson, Paul; Wenaus, Torre

2015-01-01

ATLAS user jobs are executed on Worker Nodes (WNs) by pilots sent to sites by pilot factories. This paradigm serves to allow a high job reliability and although it has clear advantages, such as making the working environment homogeneous, the approach presents security and traceability challenges. To address these challenges, gLExec can be used to let the payloads for each user be executed under a different UNIX user id that uniquely identifies the ATLAS user. This paper describes the recent improvements and evolution of the security model within the ATLAS PanDA system, including improvements in the PanDA pilot, in the PanDA server and their integration with MyProxy, a credential caching system that entitles a person or a service to act in the name of the issuer of the credential. Finally, it presents results from ATLAS user jobs running with gLExec and describes the deployment campaign within ATLAS.

ATLAS Global Shares Implementation in the PanDA Workload Management System

CERN Document Server

Barreiro Megino, Fernando Harald; The ATLAS collaboration

2018-01-01

PanDA (Production and Distributed Analysis) is the workload management system for ATLAS across the Worldwide LHC Computing Grid. While analysis tasks are submitted to PanDA by over a thousand users following personal schedules (e.g. PhD or conference deadlines), production campaigns are scheduled by a central Physics Coordination group based on the organization’s calendar. The Physics Coordination group needs to allocate the amount of Grid resources dedicated to each activity, in order to manage sharing of CPU resources among various parallel campaigns and to make sure that results can be achieved in time for important deadlines. While dynamic and static shares on batch systems have been around for a long time, we are trying to move away from local resource partitioning and manage shares at a global level in the PanDA system. The global solution is not straightforward, given different requirements of the activities (number of cores, memory, I/O and CPU intensity), the heterogeneity of Grid resources (site/H...

Integration Of PanDA Workload Management System With Supercomputers for ATLAS

CERN Document Server

Oleynik, Danila; The ATLAS collaboration; De, Kaushik; Wenaus, Torre; Maeno, Tadashi; Barreiro Megino, Fernando Harald; Nilsson, Paul; Guan, Wen; Panitkin, Sergey

2016-01-01

The Large Hadron Collider (LHC), operating at the international CERN Laboratory in Geneva, Switzerland, is leading Big Data driven scientific explorations. Experiments at the LHC explore the fundamental nature of matter and the basic forces that shape our universe, and were recently credited for the discovery of a Higgs boson. ATLAS, one of the largest collaborations ever assembled in the sciences, is at the forefront of research at the LHC. To address an unprecedented multi-petabyte data processing challenge, the ATLAS experiment is relying on a heterogeneous distributed computational infrastructure. The ATLAS experiment uses PanDA (Production ANd Distributed Analysis system) Workload Management System for managing the workflow for all data processing on over 150 data centers. Through PanDA, ATLAS physicists see a single computing facility that enables rapid scientific breakthroughs for the experiment, even though the data centers are physically scattered all over the world. While PanDA currently uses more t...

Pulse pile-up recovery for the front-end electronics of the PANDA Electromagnetic Calorimeter

NARCIS (Netherlands)

Tambave, G.; Kavatsyuk, M.; Guliyev, E.; Schreuder, F.; Moeini, H.; Löhner, H.

2012-01-01

At the future Facility for Antiproton and Ion Research near Darmstadt in Germany the PANDA detector will be employed to study the charmonium spectrum and to search for narrow exotic hadronic states, predicted by Quantum Chromodynamics. In the PANDA experiment, 1.5 to 15GeV/c anti-protons will

Pulse pile-up recovery for the front-end electronics of the PANDA Electromagnetic Calorimeter

NARCIS (Netherlands)

Tambave, G.; Kavatsyuk, M.; Guliyev, E.; Schreuder, F.; Moeini, H.; Löhner, H.

At the future Facility for Antiproton and Ion Research near Darmstadt in Germany the PANDA detector will be employed to study the charmonium spectrum and to search for narrow exotic hadronic states, predicted by Quantum Chromodynamics. In the PANDA experiment, 1.5 to 15GeV/c anti-protons will

Pulse pile-up recovery for the front-end electronics of the PANDA Electromagnetic Calorimeter

NARCIS (Netherlands)

Tambave, G.; Guliyev, E.; Kavatsyuk, M.; Schreuder, F.; Löhner, H.

2011-01-01

To study the Charmonium spectrum and search for narrow exotic hadronic states, predicted by Quantum Chromodynamics, the PANDA detector will be employed at the future Facility for Antiproton and Ion Research near Darmstadt in Germany. In the PANDA experiment, 1.5 to 15 GeV/c anti-protons will collide

Cognitive screening in Parkinson's disease: Comparison of the Parkinson Neuropsychometric Dementia Assessment (PANDA) with 3 other short scales.

Science.gov (United States)

Gasser, A-I; Calabrese, P; Kalbe, E; Kessler, J; Rossier, P

2016-02-01

Cognitive screening is crucial in Parkinson's disease (PD). However, there is still a lack of short tools in French. In this study, we aimed to compare the Parkinson Neuropsychometric Dementia Assessment (PANDA) with the Mini Mental Parkinson (MMP), the Mini Mental State Examination (MMSE) and the Clock Test in French-speaking patients. We also aimed to propose cut-off scores for cognitive impairment and dementia for the French language version of the PANDA. Fifty-one patients with PD took the PANDA, the MMSE, the MMP, and the Clock Test. They also underwent extensive neuropsychological testing by a neuropsychologist who was blinded to the above-mentioned screening test results. Patients were classified as either having normal cognition (n=15), mild cognitive impairment (n=20) or dementia (n=16). When compared with the three other screening tools, the PANDA exhibited the highest area under the curve (AUC) for both cognitive disorders and dementia. Using the cut-off scores proposed for the German version, the PANDA had 94% specificity and 100% sensitivity for dementia and 100% and 72%, respectively for cognitive disorders. In our study, the PANDA exhibited a higher discriminative power than the three other tests in detecting cognitive disorders and dementia. In PD patients, the PANDA should thus be considered for the detection of cognitive impairment in routine clinical practice. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

Cloning and characterization of giant panda (Ailuropoda melanoleuca) IL-18 binding protein.

Science.gov (United States)

Yan, Yue; Deng, Jiabo; Niu, Lili; Wang, Qiang; Yu, Jianqiu; Shao, Huanhuan; Cao, Qinghua; Zhang, Yizheng; Tan, Xuemei

2016-06-01

The giant panda (Ailuropoda melanoleuca) is an endangered species. Interleukin-18 (IL-18) plays an important role in the innate and adaptive immune responses by inducing IFN-γ. IL-18 has been implicated in the pathogenesis of various diseases. IL-18 binding protein (IL-18BP) is an intrinsic inhibitor of IL-18 that possesses higher affinity to IL-18. In this study, we cloned and characterized IL-18BP in giant panda (AmIL-18BP) from the spleen. The amino acid sequence of giant panda IL-18BP ORF shared about 65% identities with other species. To evaluate the effects of AmIL-18BP on the immune responses, we expressed the recombinant AmIL-18BP in Escherichia coli BL21 (DE3).The fusing protein PET-AmIL-18BP was purified by nickel affinity column chromatography. The biological function of purified PET-AmIL-18BP was determined on mice splenocyte by qRT-PCR. The results showed that AmIL-18BP was functional and could significantly reduce IFN-γ production in murine splenocytes. These results will facilitate the study of protecting giant panda on etiology and immunology. Copyright © 2016 Elsevier Ltd. All rights reserved.

Tics, OCD and Streptococcal Infection (PANDAS

Directory of Open Access Journals (Sweden)

J Gordon Millichap

2008-07-01

Full Text Available Forty matched pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS case-control pairs were prospectively evaluated clinically and with testing for group A b-hemolytic streptococcus for an average of 2 years, in a study at University of Rochester School of Medicine, New York; and WHO Streptococcal Reference Laboratory, Minneapolis, MN.

PERCEPCIÓN DEL LIDERAZGO EN LAS(OS) ENFERMERAS(OS) DE UN HOSPITAL DEL SUR DE CHILE

OpenAIRE

Quezada Torres,Cyntia; Illesca Pretty,Mónica; Cabezas González,Mirtha

2014-01-01

Objetivo: Conocer la percepción del Liderazgo en las(os) Enfermeras(os) de un Hospital del Sur de Chile. Método: Se realizó una investigación cualitativa, descriptiva, exploratoria e interpretativa a través de un estudio de caso único. Los informantes claves fueron seis Enfermeras(os) que se desempeñan en puestos de responsabilidad. La recolección de datos fue mediante grupo focal. El análisis siguió un esquema a través de la reducción progresiva (separación de unidades, agrupamiento, identif...

Online software trigger at PANDA/FAIR

Energy Technology Data Exchange (ETDEWEB)

Kang, Donghee; Kliemt, Ralf; Nerling, Frank [Helmholtz-Institut Mainz (Germany); Denig, Achim [Institut fuer Kernphysik, Universitaet Mainz (Germany); Goetzen, Klaus; Peters, Klaus [GSI Helmholtzzentrum fuer Schwerionenforschung GmbH (Germany); Collaboration: PANDA-Collaboration

2014-07-01

The PANDA experiment at FAIR will employ a novel trigger-less read-out system. Since a conventional hardware trigger concept is not suitable for PANDA, a high level online event filter will be applied to perform fast event selection based on physics properties of the reconstructed events. A trigger-less data stream implies an event selection with track reconstruction and pattern recognition to be performed online, and thus analysing data under real time conditions at event rates of up to 40 MHz.The projected data rate reduction of about three orders of magnitude requires an effective background rejection, while retaining interesting signal events. Real time event selection in the environment of hadronic reactions is rather challenging and relies on sophisticated algorithms for the software trigger. The implementation and the performance of physics trigger algorithms presently studied with realistic Monte Carlo simulations is discussed. The impact of parameters such as momentum or mass resolution, PID probability, vertex reconstruction and a multivariate analysis using the TMVA package for event filtering is presented.

Parasites of the Giant Panda: A Risk Factor in the Conservation of a Species.

Science.gov (United States)

Wang, Tao; Xie, Yue; Zheng, Youle; Wang, Chengdong; Li, Desheng; Koehler, Anson V; Gasser, Robin B

2018-01-01

The giant panda, with an estimated population size of 2239 in the world (in 2015), is a global symbol of wildlife conservation that is threatened by habitat loss, poor reproduction and limited resistance to some infectious diseases. Of these factors, some diseases caused by parasites are considered as the foremost threat to its conservation. However, there is surprisingly little published information on the parasites of the giant panda, most of which has been disseminated in the Chinese literature. Herein, we review all peer-reviewed publications (in English or Chinese language) and governmental documents for information on parasites of the giant pandas, with an emphasis on the intestinal nematode Baylisascaris schroederi (McIntosh, 1939) as it dominates published literature. The purpose of this chapter is to: (i) review the parasites recorded in the giant panda and describe what is known about their biology; (ii) discuss key aspects of the pathogenesis, diagnosis, treatment and control of key parasites that are reported to cause clinical problems and (iii) conclude by making some suggestions for future research. This chapter shows that we are only just 'scratching the surface' when it comes to parasites and parasitological research of the giant panda. Clearly, there needs to be a concerted research effort to support the conservation of this iconic species. © 2018 Elsevier Ltd All rights reserved.

Characterization and Analysis of Whole Transcriptome of Giant Panda Spleens: Implying Critical Roles of Long Non-Coding RNAs in Immunity.

Science.gov (United States)

Peng, Rui; Liu, Yuliang; Cai, Zhigang; Shen, Fujun; Chen, Jiasong; Hou, Rong; Zou, Fangdong

2018-01-01

Giant pandas, an endangered species, are a powerful symbol of species conservation. Giant pandas may suffer from a variety of diseases. Owing to their highly specialized diet of bamboo, giant pandas are thought to have a relatively weak ability to resist diseases. The spleen is the largest organ in the lymphatic system. However, there is little known about giant panda spleen at a molecular level. Thus, clarifying the regulatory mechanisms of spleen could help us further understand the immune system of the giant panda as well as its conservation. The two giant panda spleens were from two male individuals, one newborn and one an adult, in a non-pathological condition. The whole transcriptomes of mRNA, lncRNA, miRNA, and circRNA in the two spleens were sequenced using the Illumina HiSeq platform. EBseq and IDEG6 were used to observe the differentially expressed genes (DEGs) between these two spleens. Gene Ontology and KEGG analyses were used to annotate the function of DEGs. Furthermore, networks between non-coding RNAs and protein-coding genes were constructed to investigate the relationship between non-coding RNAs and immune-associated genes. By comparative analysis of the whole transcriptomes of these two spleens, we found that one of the major roles of lncRNAs could be involved in the regulation of immune responses of giant panda spleens. In addition, our results also revealed that microRNAs and circRNAs may have evolved to regulate a large set of biological processes of giant panda spleens, and circRNAs may function as miRNA sponges. To our knowledge, this is the first report of lncRNAs and circRNAs in giant panda, which could be a useful resource for further giant panda research. Our study reveals the potential functional roles of miRNAs, lncRNAs, and circRNAs in giant panda spleen. © 2018 The Author(s). Published by S. Karger AG, Basel.

Characterization and Analysis of Whole Transcriptome of Giant Panda Spleens: Implying Critical Roles of Long Non-Coding RNAs in Immunity

Directory of Open Access Journals (Sweden)

Rui Peng

2018-04-01

Full Text Available Background/Aims: Giant pandas, an endangered species, are a powerful symbol of species conservation. Giant pandas may suffer from a variety of diseases. Owing to their highly specialized diet of bamboo, giant pandas are thought to have a relatively weak ability to resist diseases. The spleen is the largest organ in the lymphatic system. However, there is little known about giant panda spleen at a molecular level. Thus, clarifying the regulatory mechanisms of spleen could help us further understand the immune system of the giant panda as well as its conservation. Methods: The two giant panda spleens were from two male individuals, one newborn and one an adult, in a non-pathological condition. The whole transcriptomes of mRNA, lncRNA, miRNA, and circRNA in the two spleens were sequenced using the Illumina HiSeq platform. EBseq and IDEG6 were used to observe the differentially expressed genes (DEGs between these two spleens. Gene Ontology and KEGG analyses were used to annotate the function of DEGs. Furthermore, networks between non-coding RNAs and protein-coding genes were constructed to investigate the relationship between non-coding RNAs and immune-associated genes. Results: By comparative analysis of the whole transcriptomes of these two spleens, we found that one of the major roles of lncRNAs could be involved in the regulation of immune responses of giant panda spleens. In addition, our results also revealed that microRNAs and circRNAs may have evolved to regulate a large set of biological processes of giant panda spleens, and circRNAs may function as miRNA sponges. Conclusion: To our knowledge, this is the first report of lncRNAs and circRNAs in giant panda, which could be a useful resource for further giant panda research. Our study reveals the potential functional roles of miRNAs, lncRNAs, and circRNAs in giant panda spleen.

gLExec and MyProxy integration in the ATLAS/OSG PanDA workload management system

International Nuclear Information System (INIS)

Caballero, J; Hover, J; Maeno, T; Potekhin, M; Wenaus, T; Zhao, X; Litmaath, M; Nilsson, P

2010-01-01

Worker nodes on the grid exhibit great diversity, making it difficult to offer uniform processing resources. A pilot job architecture, which probes the environment on the remote worker node before pulling down a payload job, can help. Pilot jobs become smart wrappers, preparing an appropriate environment for job execution and providing logging and monitoring capabilities. PanDA (Production and Distributed Analysis), an ATLAS and OSG workload management system, follows this design. However, in the simplest (and most efficient) pilot submission approach of identical pilots carrying the same identifying grid proxy, end-user accounting by the site can only be done with application-level information (PanDA maintains its own end-user accounting), and end-user jobs run with the identity and privileges of the proxy carried by the pilots, which may be seen as a security risk. To address these issues, we have enabled PanDA to use gLExec, a tool provided by EGEE which runs payload jobs under an end-user's identity. End-user proxies are pre-staged in a credential caching service, MyProxy, and the information needed by the pilots to access them is stored in the PanDA DB. gLExec then extracts from the user's proxy the proper identity under which to run. We describe the deployment, installation, and configuration of gLExec, and how PanDA components have been augmented to use it. We describe how difficulties were overcome, and how security risks have been mitigated. Results are presented from OSG and EGEE Grid environments performing ATLAS analysis using PanDA and gLExec.

Risk Assessment of Canine Distemper in the Distribution Area of Giant Panda in Sichuan, Shaanxi and Gansu Provinces, China

Directory of Open Access Journals (Sweden)

Weigeng Shao

2017-11-01

Full Text Available Giant panda is the world-class precious endangered species, facing the canine distemper and other important infectious diseases on its wild and captive population of a serious threat. In this study, we used MaxEnt model and combined with ArcGIS analysis to predict the potential risk of canine distemper to giant panda habitat in Sichuan, Gansu and Shaanxi Provinces, China. The results showed that 35.05% and 19.47% of the distribution areas of the giant pandas were in the high risk and medium risk of canine distemper, respectively. The canine distemper pose a great risk to the healthy survival of giant pandas in China. In future, epidemic prevention, vaccine development and application of wild animals should be enhanced so as to effectively protect the giant panda.

El rastre dels més desvalguts entre els papers de l'Hospital de Barcelona

Directory of Open Access Journals (Sweden)

Teresa Vinyoles Vidal

2013-12-01

Full Text Available Aquest text, que té el seu origen en la ponència que vam presentar al simposi internacional Fonts gràfiques i documentals per a l’estudi històric dels hospitals (abril 2013, pretén oferir un petit mostrari de la informació que es pot extreure i les conclusions que se’n deriven, de la consulta directa de les fonts documentals de l’antic hospital de la Santa Creu de Barcelona. El punt de partida de la nostra recerca s’emmarca en els mateixos orígens històrics d’aquesta centenària institució, és a dir, l’albada del segle XV. En aquest sentit, bàsicament hem fet servir els llibres d’entrades de malalts i d’expòsits, un minutari comptable i uns manuals notarials del quatre-cents i d’èpoques posteriors, conservats a la Biblioteca de Catalunya i a l’Arxiu Històric de la Fundació de l’Hospital de la Santa Creu i Sant Pau. El nostre propòsit no és fer-ne un estat de la qüestió, ni esbossar una història de la pobresa barcelonina, ni tampoc plantejar una visió comparativa de les institucions hospitalàries, senzillament, després de reflexionar sobre el tema, mirarem de dialogar amb les fonts i que siguin elles les que parlin. Procurarem, en el possible, sentir la veu dels pobres del passat, però sense oblidar que la pobresa no és propietat exclusiva dels temps medievals.

Isolation and Preliminary Screening of a Weissella confusa Strain from Giant Panda (Ailuropoda melanoleuca).

Science.gov (United States)

Xiong, Lvchen; Ni, Xueqin; Niu, Lili; Zhou, Yi; Wang, Qiang; Khalique, Abdul; Liu, Qian; Zeng, Yan; Shu, Gang; Pan, Kangcheng; Jing, Bo; Zeng, Dong

2018-04-13

Weissella confusa has recently received attention for its probiotic potential. Some W. confusa and Weissella cibaria strains isolated from fermented foods show favorable probiotic effects. However, the probiotic properties of W. confusa isolated from giant panda remain unreported to date. Thus, this study isolated a W. confusa strain from giant panda feces and then investigated its characteristics and probiotic properties. A lactic acid bacteria strain was isolated from giant panda fecal samples. The isolated strain was screened by in vitro probiotic property tests, including in vitro antimicrobial test, antioxidant test, surface hydrophobicity, and stress resistance. On the basis of biochemical identification and 16S rDNA sequencing, the W. confusa strain was identified as BSP201703. This Weissella confusa strain can survive at pH 2 and 0.3% (w/v) concentration of bile salt environment and inhibit common intestinal pathogens. It also possesses an in vitro antioxidant capacity, a high auto-aggregation ability, and a high surface hydrophobicity. BSP201703 might serve as a probiotic to giant pandas.

Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS: An Evolving Concept

Directory of Open Access Journals (Sweden)

Antonella Macerollo

2013-09-01

Full Text Available Pediatric autoimmune neuropsychiatric disorders associated with streptococcus infections (PANDAS originated from the observational work of Swedo and collaborators, who formalized their definition in 1998 in a set of operational criteria. The application of these criteria, which focuses on tics and obsessive-compulsive symptoms as core symptoms, has encountered difficulties, eventually leading to a high rate of misdiagnosis. In particular, the core feature represented by the association between newly diagnosed infections and neuropsychiatric symptom relapses in youths with this diagnosis could not be demonstrated by longitudinal studies. Exploratory studies aiming to identify clinical or cognitive features that could discriminate PANDAS from other pediatric obsessive-compulsive and tic disorders present methodological limitations, and therefore are not conclusive. Other behavioral features, in addition to obsessive-compulsive symptoms and tics, have been included in pediatric acute-onset neuropsychiatric syndromes (PANS and childhood acute neuropsychiatric syndromes (CANS, two new concepts recently proposed in order to define a much broader clinical spectrum encompassing etiologically diverse entities. Given the uncertainties on the clinical definition of PANDAS, it is not surprising that evidence in support of a post-infectious, immune-mediated pathophysiology is also insufficient. Anti-dopamine receptor antibodies might be relevant to both Sydenham’s chorea (SC—the prototypical post-streptococcal neuropsychiatric disorder—and some rare forms of encephalitis targeting the basal ganglia specifically, but studies exploring their association with children fulfilling Swedo’s criteria for PANDAS have been inconclusive. Moreover, we lack evidence in favor of the efficacy of antibiotic prophylaxis or tonsillectomy in patients fulfilling Swedo’s criteria for PANDAS, whereas a response to immune-mediated treatments like intravenous

Producción científica institucional y posicionamiento nacional: el caso del Hospital General de México

Directory of Open Access Journals (Sweden)

Macías-Chapula, C. A.

2004-12-01

Full Text Available The purpose of this work was to identify the scientific output, position and visibility of Mexico’s General Hospital (Hospital General de México-HGM. A literature search in the following databases was conducted for the period 1990-2003, in order to obtain the hospital’s scientific production: NCR, MEDLINE, LILACS, ARTEMISA, PERIODICA, and CLASE. The hospital scientific visibility was identified through the analysis of 140 documents retrieved from MEDLINE, for the period 1999-2003. Similarly, in order to obtain the scientific position of HGM at the national level, a bibliographic search was conducted in NCR and MEDLINE. Data were analyzed both manually and through BIBEXCEL 2001 and EXCEL 2000. Results included the retrieval of 1.647 references from the above mentioned databases. The subject content visibility indicated that the scientific production of the hospital was mainly related to comparative studies, treatment, and retrospective studies. As for the scientific position of the hospital, a rank 9 (r = 1-78in NCR and rank 12 (r = 1-74 in MEDLINE, was obtained. The study obtained the production, scientific position and visibility of the hospital through the databases used. HGM scientific production showed a high trend in the clinical medicine area and a low productivity in the social and humanistic fields. The thematic production of the hospital does not coincide with its main mortality causes; however, the hospital remains within the main 15 health research institutions at a national level. Finally, the document describes the implications of the study and the needed research actions, in order to support the adequate science policy lines of the hospital.

El propósito de este trabajo fue el de identificar la producción, visibilidad y posicionamiento científico del Hospital General de México (HGM. Para la identificación de la producción del hospital, se condujo una investigación bibliográfica en las siguientes bases de datos

The PANDA experiment: Antiproton physics at FAIR

International Nuclear Information System (INIS)

Montagna, P.

2011-01-01

The new Facility for Antiproton and Ion Research (FAIR), under construction at the GSI laboratory at Darmstadt, in a few years will make available, among different types of beams, even antiproton beams with unique features. Through a High Energy Storage Ring (HESR) for antiprotons, an antiproton beam will be available in a momentum range from 1.5 to 15 GeV/c, which will interact on a hydrogen target. The products of the interaction, including hadronic systems with strangeness and/or charm, will be detected with the PANDA magnetic spectrometer (antiProton ANnihilation at DArmstadt), and the spectroscopic analysis will allow a detailed investigation on a number of open problems of the hadronic physics, as the quark confinement, the existence of non-conventional meson states (so-called glueballs and hybrids), the structure of hadrons and of the strong interaction, with particular attention to charmonium spectroscopy. An overview of the scientific program of PANDA and the current status of the project will be presented.

[Assessment of ecosystem in giant panda distribution area based on entropy method and coefficient of variation].

Science.gov (United States)

Yan, Zhi Gang; Li, Jun Qing

2017-12-01

The areas of the habitat and bamboo forest, and the size of the giant panda wild population have greatly increased, while habitat fragmentation and local population isolation have also intensified in recent years. Accurate evaluation of ecosystem status of the panda in the giant panda distribution area is important for giant panda conservation. The ecosystems of the distribution area and six mountain ranges were subdivided into habitat and population subsystems based on the hie-rarchical system theory. Using the panda distribution area as the study area and the three national surveys as the time node, the evolution laws of ecosystems were studied using the entropy method, coefficient of variation, and correlation analysis. We found that with continuous improvement, some differences existed in the evolution and present situation of the ecosystems of six mountain ranges could be divided into three groups. Ecosystems classified into the same group showed many commonalities, and difference between the groups was considerable. Problems of habitat fragmentation and local population isolation became more serious, resulting in ecosystem degradation. Individuali-zed ecological protection measures should be formulated and implemented in accordance with the conditions in each mountain system to achieve the best results.

Giant panda (Ailuropoda melanoleuca) population dynamics and bamboo (subfamily Bambusoideae) life history: a structured population approach to examining carrying capacity when the prey are semelparous

Science.gov (United States)

Carter, J.; Ackleh, A.S.; Leonard, B.P.; Wang, Hongfang

1999-01-01

The giant panda, Ailuropoda melanoleuca, is a highly specialized Ursid whose diet consists almost entirely of various species of bamboo. Bamboo (Bambusoideae) is a grass subfamily whose species often exhibit a synchronous semelparity. Synchronous semelparity can create local drops in carrying capacity for the panda. We modeled the interaction of pandas and their bamboo food resources with an age structured panda population model linked to a natural history model of bamboo biomass dynamics based on literature values of bamboo biomass, and giant panda life history dynamics. This paper reports the results of our examination of the interaction between pandas and their bamboo food resource and its implications for panda conservation. In the model all panda populations were well below the carrying capacity of the habitat. The giant panda populations growth was most sensitive to changes in birth rates and removal of reproductive aged individuals. Periodic starvation that has been documented in conjunction with bamboo die-offs is probably related to the inability to move to other areas within the region where bamboo is still available. Based on the results of this model, giant panda conservation should concentrate on keeping breeding individuals in the wild, keep corridors to different bamboo species open to pandas, and to concentrate research on bamboo life history.

PANDA-view: An easy-to-use tool for statistical analysis and visualization of quantitative proteomics data.

Science.gov (United States)

Chang, Cheng; Xu, Kaikun; Guo, Chaoping; Wang, Jinxia; Yan, Qi; Zhang, Jian; He, Fuchu; Zhu, Yunping

2018-05-22

Compared with the numerous software tools developed for identification and quantification of -omics data, there remains a lack of suitable tools for both downstream analysis and data visualization. To help researchers better understand the biological meanings in their -omics data, we present an easy-to-use tool, named PANDA-view, for both statistical analysis and visualization of quantitative proteomics data and other -omics data. PANDA-view contains various kinds of analysis methods such as normalization, missing value imputation, statistical tests, clustering and principal component analysis, as well as the most commonly-used data visualization methods including an interactive volcano plot. Additionally, it provides user-friendly interfaces for protein-peptide-spectrum representation of the quantitative proteomics data. PANDA-view is freely available at https://sourceforge.net/projects/panda-view/. 1987ccpacer@163.com and zhuyunping@gmail.com. Supplementary data are available at Bioinformatics online.

Integration Of PanDA Workload Management System With Supercomputers for ATLAS and Data Intensive Science

Science.gov (United States)

Klimentov, A.; De, K.; Jha, S.; Maeno, T.; Nilsson, P.; Oleynik, D.; Panitkin, S.; Wells, J.; Wenaus, T.

2016-10-01

The.LHC, operating at CERN, is leading Big Data driven scientific explorations. Experiments at the LHC explore the fundamental nature of matter and the basic forces that shape our universe. ATLAS, one of the largest collaborations ever assembled in the sciences, is at the forefront of research at the LHC. To address an unprecedented multi-petabyte data processing challenge, the ATLAS experiment is relying on a heterogeneous distributed computational infrastructure. The ATLAS experiment uses PanDA (Production and Data Analysis) Workload Management System for managing the workflow for all data processing on over 150 data centers. Through PanDA, ATLAS physicists see a single computing facility that enables rapid scientific breakthroughs for the experiment, even though the data centers are physically scattered all over the world. While PanDA currently uses more than 250,000 cores with a peak performance of 0.3 petaFLOPS, LHC data taking runs require more resources than grid can possibly provide. To alleviate these challenges, LHC experiments are engaged in an ambitious program to expand the current computing model to include additional resources such as the opportunistic use of supercomputers. We will describe a project aimed at integration of PanDA WMS with supercomputers in United States, in particular with Titan supercomputer at Oak Ridge Leadership Computing Facility. Current approach utilizes modified PanDA pilot framework for job submission to the supercomputers batch queues and local data management, with light-weight MPI wrappers to run single threaded workloads in parallel on LCFs multi-core worker nodes. This implementation was tested with a variety of Monte-Carlo workloads on several supercomputing platforms for ALICE and ATLAS experiments and it is in full pro duction for the ATLAS since September 2015. We will present our current accomplishments with running PanDA at supercomputers and demonstrate our ability to use PanDA as a portal independent of the

Integration Of PanDA Workload Management System With Supercomputers for ATLAS and Data Intensive Science

International Nuclear Information System (INIS)

Klimentov, A; Maeno, T; Nilsson, P; Panitkin, S; Wenaus, T; De, K; Oleynik, D; Jha, S; Wells, J

2016-01-01

The.LHC, operating at CERN, is leading Big Data driven scientific explorations. Experiments at the LHC explore the fundamental nature of matter and the basic forces that shape our universe. ATLAS, one of the largest collaborations ever assembled in the sciences, is at the forefront of research at the LHC. To address an unprecedented multi-petabyte data processing challenge, the ATLAS experiment is relying on a heterogeneous distributed computational infrastructure. The ATLAS experiment uses PanDA (Production and Data Analysis) Workload Management System for managing the workflow for all data processing on over 150 data centers. Through PanDA, ATLAS physicists see a single computing facility that enables rapid scientific breakthroughs for the experiment, even though the data centers are physically scattered all over the world. While PanDA currently uses more than 250,000 cores with a peak performance of 0.3 petaFLOPS, LHC data taking runs require more resources than grid can possibly provide. To alleviate these challenges, LHC experiments are engaged in an ambitious program to expand the current computing model to include additional resources such as the opportunistic use of supercomputers. We will describe a project aimed at integration of PanDA WMS with supercomputers in United States, in particular with Titan supercomputer at Oak Ridge Leadership Computing Facility. Current approach utilizes modified PanDA pilot framework for job submission to the supercomputers batch queues and local data management, with light-weight MPI wrappers to run single threaded workloads in parallel on LCFs multi-core worker nodes. This implementation was tested with a variety of Monte-Carlo workloads on several supercomputing platforms for ALICE and ATLAS experiments and it is in full pro duction for the ATLAS since September 2015. We will present our current accomplishments with running PanDA at supercomputers and demonstrate our ability to use PanDA as a portal independent of the

Calidad del llenado del certificado de defunción y muerte fetal en un hospital de segundo nivel en México

OpenAIRE

Henández Mier, C.

2014-01-01

l os certificados de defunción y muerte fetal son de valor legal, epidemiológico y es tadístico, el objetivo del presente estudio es proponer un modelo objetivo y evaluar la calidad del llenado en un hospital de segundo nivel en México. Metodologí a: Se realizó un estudio observacional, descriptivo, retrospectivo, tomando como variables los requisitos establecidos en la Guía Para el Llenado del Certificado de Defunción y del Certificado de Muerte Fetal. La evaluación de l...

Giant Panda (Ailuropoda melanoleuca) Buccal Mucosa Tissue as a Source of Multipotent Progenitor Cells.

Science.gov (United States)

Prescott, Hilary M A; Manning, Craig; Gardner, Aaron; Ritchie, William A; Pizzi, Romain; Girling, Simon; Valentine, Iain; Wang, Chengdong; Jahoda, Colin A B

2015-01-01

Since the first mammal was cloned, the idea of using this technique to help endangered species has aroused considerable interest. However, several issues limit this possibility, including the relatively low success rate at every stage of the cloning process, and the dearth of usable tissues from these rare animals. iPS cells have been produced from cells from a number of rare mammalian species and this is the method of choice for strategies to improve cloning efficiency and create new gametes by directed differentiation. Nevertheless information about other stem cell/progenitor capabilities of cells from endangered species could prove important for future conservation approaches and adds to the knowledge base about cellular material that can be extremely limited. Multipotent progenitor cells, termed skin-derived precursor (SKP) cells, can be isolated directly from mammalian skin dermis, and human cheek tissue has also been shown to be a good source of SKP-like cells. Recently we showed that structures identical to SKPs termed m-SKPs could be obtained from monolayer/ two dimensional (2D) skin fibroblast cultures. Here we aimed to isolate m-SKPs from cultured cells of three endangered species; giant panda (Ailuropoda melanoleuca); red panda (Ailurus fulgens); and Asiatic lion (Panthera leo persica). m-SKP-like spheres were formed from the giant panda buccal mucosa fibroblasts; whereas dermal fibroblast (DF) cells cultured from abdominal skin of the other two species were unable to generate spheres. Under specific differentiation culture conditions giant panda spheres expressed neural, Schwann, adipogenic and osteogenic cell markers. Furthermore, these buccal mucosa derived spheres were shown to maintain expression of SKP markers: nestin, versican, fibronectin, and P75 and switch on expression of the stem cell marker ABCG2. These results demonstrate that giant panda cheek skin can be a useful source of m-SKP multipotent progenitors. At present lack of sample numbers

Giant Panda (Ailuropoda melanoleuca Buccal Mucosa Tissue as a Source of Multipotent Progenitor Cells.

Directory of Open Access Journals (Sweden)

Hilary M A Prescott

Full Text Available Since the first mammal was cloned, the idea of using this technique to help endangered species has aroused considerable interest. However, several issues limit this possibility, including the relatively low success rate at every stage of the cloning process, and the dearth of usable tissues from these rare animals. iPS cells have been produced from cells from a number of rare mammalian species and this is the method of choice for strategies to improve cloning efficiency and create new gametes by directed differentiation. Nevertheless information about other stem cell/progenitor capabilities of cells from endangered species could prove important for future conservation approaches and adds to the knowledge base about cellular material that can be extremely limited. Multipotent progenitor cells, termed skin-derived precursor (SKP cells, can be isolated directly from mammalian skin dermis, and human cheek tissue has also been shown to be a good source of SKP-like cells. Recently we showed that structures identical to SKPs termed m-SKPs could be obtained from monolayer/ two dimensional (2D skin fibroblast cultures. Here we aimed to isolate m-SKPs from cultured cells of three endangered species; giant panda (Ailuropoda melanoleuca; red panda (Ailurus fulgens; and Asiatic lion (Panthera leo persica. m-SKP-like spheres were formed from the giant panda buccal mucosa fibroblasts; whereas dermal fibroblast (DF cells cultured from abdominal skin of the other two species were unable to generate spheres. Under specific differentiation culture conditions giant panda spheres expressed neural, Schwann, adipogenic and osteogenic cell markers. Furthermore, these buccal mucosa derived spheres were shown to maintain expression of SKP markers: nestin, versican, fibronectin, and P75 and switch on expression of the stem cell marker ABCG2. These results demonstrate that giant panda cheek skin can be a useful source of m-SKP multipotent progenitors. At present lack of

PanDA: A New Paradigm for Distributed Computing in HEP Through the Lens of ATLAS and other Experiments

CERN Document Server

De, K; The ATLAS collaboration; Maeno, T; Nilsson, P; Wenaus, T

2014-01-01

Experiments at the Large Hadron Collider (LHC) face unprecedented computing challenges. Heterogeneous resources are distributed worldwide, thousands of physicists analyzing the data need remote access to hundreds of computing sites, the volume of processed data is beyond the exabyte scale, and data processing requires more than a billion hours of computing usage per year. The PanDA (Production and Distributed Analysis) system was developed to meet the scale and complexity of LHC distributed computing for the ATLAS experiment. In the process, the old batch job paradigm of computing in HEP was discarded in favor of a far more flexible and scalable model. The success of PanDA in ATLAS is leading to widespread adoption and testing by other experiments. PanDA is the first exascale workload management system in HEP, already operating at a million computing jobs per day, and processing over an exabyte of data in 2013. We will describe the design and implementation of PanDA, present data on the performance of PanDA a...

Non-conventional mesons at PANDA

International Nuclear Information System (INIS)

Giacosa, Francesco

2015-01-01

Non-conventional mesons, such as glueballs and tetraquarks, will be in the focus of the PANDA experiment at the FAIR facility. In this lecture we recall the basic properties of QCD and describe some features of unconventional states. We focus on the search of the not-yet discovered glueballs and the use of the extended Linear Sigma Model for this purpose, and on the already discovered but not-yet understood X, Y, Z states. (paper)

The PANDA Endcap Disc DIRC

Science.gov (United States)

Föhl, K.; Ali, A.; Belias, A.; Dzhygadlo, R.; Gerhardt, A.; Götzen, K.; Kalicy, G.; Krebs, M.; Lehmann, D.; Nerling, F.; Patsyuk, M.; Peters, K.; Schepers, G.; Schmitt, L.; Schwarz, C.; Schwiening, J.; Traxler, M.; Böhm, M.; Eyrich, W.; Lehmann, A.; Pfaffinger, M.; Uhlig, F.; Düren, M.; Etzelmüller, E.; Hayrapetyan, A.; Kreutzfeld, K.; Merle, O.; Rieke, J.; Schmidt, M.; Wasem, T.; Achenbach, P.; Cardinali, M.; Hoek, M.; Lauth, W.; Schlimme, S.; Sfienti, C.; Thiel, M.

2018-02-01

Positively identifying charged kaons in the PANDA forward endcap solid angle range can be achieved with the Endcap Disc DIRC, allowing kaon-pion separation from 1 up to 4 GeV/c with a separation power of at least 3 standard deviations. Design, performance, and components of this DIRC are given, including the recently introduced TOFPET-ASIC based read-out. Results of a prototype operated in a test beam at DESY in 2016 are shown.

[Expression of neuropeptide Y and long leptin receptor in gastrointestinal tract of giant panda].

Science.gov (United States)

Luo, Qihui; Tang, Xiuying; Chen, Zhengli; Wang, Kaiyu; Wang, Chengdong; Li, Desheng; Li, Caiwu

2015-08-01

To study the expression and distribution of neuropeptide Y (NPY) and long leptin receptor (OB-Rb) in the gastrointestinal tract of giant panda, samples of three animals were collected from the key laboratory for reproduction and conservation genetics of endangered wildlife of Sichuan province, China conservation and research center for the giant panda. Paraffin sections of giant panda gastrointestinal tissue samples were observed using hematoxylin-eosin staining (HE) and strept actividin-biotin complex immunohistochemical staining (IHC). The results show that the intestinal histology of three pandas was normal and no pathological changes, and there were rich single-cell and multi-cell mucous glands, long intestinal villi and thick muscularis mucosa and muscle layer. Positive cells expressing NPY and OB-Rb were widely detected in the gastrointestinal tract by IHC methods. NPY positive nerve fibers and neuronal cell were widely distributed in submucosal plexus and myenteric plexus, especially in the former. They were arranged beaded or point-like shape. NPY positive cells were observed in the shape of ellipse and polygon and mainly located in the mucous layer and intestinal glands. OB-Rb positive cells were mainly distributed in the mucous layer and the laminae propria, especially the latter. These results confirmed that NPY and OB-Rb are widely distributed in the gut of the giant panda, which provide strong reference for the research between growth and development, digestion and absorption, and immune function.

Development of a GEM-based TPC for PANDA

Energy Technology Data Exchange (ETDEWEB)

Hoeppner, Christian; Ketzer, Bernhard; Konorov, Igor; Mann, Alexander; Neubert, Sebastian; Paul, Stephan; Weitzel, Quirin; Woerner, Lisa [Technische Universitaet Muenchen, Physik Department E18, 85748 Garching (Germany)

2008-07-01

A TPC is considered as the central tracker of the PANDA experiment, which is currently being planned at the new accelerator complex FAIR at Darmstadt. PANDA is designed as an internal target experiment at the antiproton storage ring HESR. The central tracker has to measure particle trajectories over a wide momentum range (0.1-8 GeV/c) from up to 2.10{sup 7} antiproton-proton annihilations/s. The continuous nature of the antiproton beam makes the use of a traditional ion gate impractical. Owing to their intrinsic ion suppression properties, GEM foils are planned as the amplification stage. A small prototype of this GEM-TPC (diameter 200 mm, drift length 77 mm) has been built and characterized with cosmic muons. Results such as spatial resolution, cluster distributions, and diffusion properties are presented in this talk.

High precision γ spectroscopy of ΛΛ-Hypernuclei at the PANDA experiment

International Nuclear Information System (INIS)

Sanchez Lorente, A

2013-01-01

Hypernuclear research will be one of the main topics addressed by the PANDA experiment at FAIR at Darmstadt (Germany). Thanks to the use of stored antiproton beams, copious production of double ΛΛ-Hypernuclei is expected at the PANDA experiment, which will enable high precision gamma spectroscopy of such nuclei for the first time. At PANDA excited states of hypernuclei will be used as a starting point for the formation of double ΛΛ-Hypernuclei. In order to predict the yield of particle-stable double hypernuclei a microcanonical decay model was developed. For the detection of these nuclei, a devoted hypernuclear detector setup is planned. This set-up consists, in addition to the general purpose of the PANDA set-up, of a primary nuclear target for the production of pairs, a secondary active target for the hypernuclei formation and the identification of associated decay products and a germanium array detector to perform gamma spectroscopy. Moreover, one of the most challenging issues of this project is the fact that all detector systems need to operate in the presence of a high magnetic field and a large hadronic background. In these proceedings details concerning the identification procedure of double hypernuclei and the suppression of background will be presented. In addition, the current status of the activities related to the detector developments for this challenging programme will be briefly given.

A Summary of the MARS Analysis Results about OECD/SETH PANDA Tests

International Nuclear Information System (INIS)

Bae, Sung Won; Chung, Bub Dong

2007-01-01

The thermal-hydraulic phenomena in a multicompartment space like the containment building under accidents are very complicated and unpredictable as a result of many interacting processes, such as sprays, hydrogen recombiners, etc. Many thermal-hydraulic phenomena, governing the containment response under postulated accidents, have been identified by the SESAR/CAF (OECD) as 'research needs' for current and advanced LWRs. Due to the recent extension of the numerical computation capability and the technology, the safety analysis field is requested to expand their analysis domain beyond the current primary system. In particular, hydrogen mixing and transport has been found to be of special importance for safety and regulation. Up to dates, OECD/CSNI has been leading many experimental projects, for example, OECD-PKL, ISP47, OECD-PANDA, focusing the gas mixing, stratification and vapor condensation phenomena. As the one of the activities, the OECD-SETH group has launched the PANDA Project in order to provide an experimental data base for a multi-dimensional code assessment in 2002. PANDA is a large scale thermal-hydraulic facility to provide a resolved experimental data base about the gas mixing and stratification phenomena. OECD-SETH group expects the PANDA Project will meet the increasing needs for adequate experimental data for a 3D distribution of relevant variables like the temperature, velocity and steam-air concentrations that are measured with a sufficient resolution and accuracy

Technical Design Report for the: PANDA Straw Tube Tracker

CERN Document Server

Erni, W; Krusche, B; Steinacher, M; Heng, Y; Liu, Z; Liu, H; Shen, X; Wang, Q; Xu, H; Aab, A; Albrecht, M; Becker, J; Csapó, A; Feldbauer, F; Fink, M; Friedel, P; Heinsius, F H; Held, T; Klask, L; Koch, H; Kopf, B; Leiber, S; Leyhe, M; Motzko, C; Pelizäus, M; Pychy, J; Roth, B; Schröder, T; Schulze, J; Sowa, C; Steinke, M; Trifterer, T; Wiedner, U; Zhong, J; Beck, R; Bianco, S; Brinkmann, K T; Hammann, C; Hinterberger, F; Kaiser, D; Kliemt, R; Kube, M; Pitka, A; Quagli, T; Schmidt, C; Schmitz, R; Schnell, R; Thoma, U; Vlasov, P; Walther, D; Wendel, C; Würschig, T; Zaunick, H G; Bianconi, A; Bragadireanu, M; Caprini, M; Pantea, D; Pantelica, D; Pietreanu, D; Serbina, L; Tarta, P D; Kaplan, D; Fiutowski, T; Idzik, M; Mindur, B; Przyborowski, D; Swientek, K; Czech, B; Kistryn, M; Kliczewski, S; Kozela, A; Kulessa, P; Lebiedowicz, P; Pysz, K; Schäfer, W; Siudak, R; Szczurek\\inst, A; Jowzaee, S; Kajetanowicz, M; Kamys, B; Kistryn, S; Korcyl, G; Korcyl, K; Krzemien, W; Magiera, A; Moskal, P; Palka, M; Rudy, Z; Salabura, P; Smyrski, J; Wrońska\\inst, A; Al-Turany, M; Arora, R; Augustin, I; Deppe, H; Flemming, H; Gerhardt, A; Götzen, K; Jordi, A F; Kalicy, G; Karabowicz, R; Lehmann, D; Lewandowski, B; Lühning, J; Maas, F; Orth, H; Patsyuk, M; Peters, K; Saito, T; Schepers, G; Schmidt, C J; Schmitt, L; Schwarz, C; Schwiening, J; Traxler, M; Voss, B; Wieczorek, P; Wilms, A; Zühlsdorf\\inst, M; Abazov, V M; Alexeev, G; Arefiev, A; Astakhov, V I; Barabanov, M Yu; Batyunya, B V; Davydov, Yu I; Dodokhov, V Kh; Efremov, A A; Fedunov, A G; Festchenko, A A; Galoyan, A S; Grigoryan, S; Karmokov, A; Koshurnikov, E K; Lobanov, V I; Lobanov, Yu Yu; Makarov, A F; Malinina, L V; Malyshev, V L; Mustafaev, G A; Olshevskiy, A; Pasyuk, M A; Perevalova, E A; Piskun, A A; Pocheptsov, T A; Pontecorvo, G; Rodionov, V K; Rogov, Yu N; Salmin, R A; Samartsev, A G; Sapozhnikov, M G; Shabratova, G S; Skachkova, A N; Skachkov, N B; Strokovsky, E A; Suleimanov, M K; Teshev, R Sh; Tokmenin, V V; Uzhinsky, V V; Vodopyanov, A S; Zaporozhets, S A; Zhuravlev, N I; Zorin, A G; Branford, D; Glazier, D; Watts, D; Woods, P; Britting, A; Eyrich, W; Lehmann, A; Uhlig, F; Dobbs, S; Metreveli, Z; Seth, K; Tomaradze, A; Xiao, T; Bettoni, D; Carassiti, V; Ramusino, A Cotta; Dalpiaz, P; Drago, A; Fioravanti, E; Garzia, I; Savriè, M; Stancari, G; Bianchi, N; Gianotti, P; Guaraldo, C; Lucherini, V; Orecchini, D; Pace, E; Bersani, A; Bracco, G; Macri, M; Parodi, R F; Bremer, D; Dormenev, V; Drexler, P; Düren, M; Eissner, T; Föhl, K; Galuska, M; Gessler, T; Hayrapetyan, A; Hu, J; Koch, P; Kröck, B; Kühn, W; Lange, S; Liang, Y; Merle, O; Metag, V; Moritz, M; Münchow, D; Nanova, M; Novotny, R; Spruck, B; Stenzel, H; Ullrich, T; Werner, M; Xu, H; Euan, C; Hoek, M; Ireland, D; Keri, T; Montgomery, R; Protopopescu, D; Rosner, G; Seitz, B; Babai, M; Glazenborg-Kluttig, A; Kavatsyuk, M; Lemmens, P; Lindemulder, M; Löhner, H; Messchendorp, J; Moeini, H; Schakel, P; Schreuder, F; Smit, H; Tambave, G; Weele, J C van der; Veenstra\\inst, R; Sohlbach, H; Büscher, M; Deermann, D; Dosdall, R; Esch, S; Gillitzer, A; Goldenbaum, F; Grunwald, D; Henssler, S; Herten, A; Hu, Q; Kemmerling, G; Kleines, H; Kozlov, V; Lehrach, A; Maier, R; Mertens, M; Ohm, H; Orfanitski, S; Prasuhn, D; Randriamalala, T; Ritman, J; Schadmand, S; Serdyuk, V; Sterzenbach, G; Stockmanns, T; Wintz, P; Wüstner, P; Xu, H; Kisiel, J; Li, S; Li, Z; Sun, Z; Xu, H; Rigato, V; Fissum, S; Hansen, K; Isaksson, L; Lundin, M; Schröder, B; Achenbach, P; Bleser, S; Cahit, U; Cardinali, M; Denig, A; Distler, M; Fritsch, M; Kangh, D; Karavdina, A; Lauth, W; Merkel, H; Michel, M; Espi, M C Mora; Müller, U; Pochodzalla, J; Prometeusz, J; Sanchez, S; Sanchez-Lorente, A; Schlimme, S; Sfienti, C; Weber\\inst, M Thiel T; Dormenev, V I; Fedorov, A A; Korzhik, M V; Missevitch, O V; Balanutsa, V; Chernetsky, V; Demekhin, A; Dolgolenko, A; Fedorets, P; Gerasimov, A; Goryachev, V; Varentsov, V; Boukharov, A; Malyshev, O; Marishev, I; Semenov, A; Böhmer, F; Dørheim, S; Ketzer, B; Paul, S; Hergemöller, A K; Khoukaz, A; Köhler, E; Täschner, A; Wessels, J; Varma, R; Chaterjee, A; Jha, V; Kailas, S; Roy, B; Yan, Y; Chinorat, K; Khanchai, K; Ayut, L; Pomrad, S; Baldin, E; Kotov, K; Peleganchuk, S; Tikhonov, Yu; Boucher, J; Chambert, V; Dbeyssi, A; Hennino, T; Imre, M; Kunne, R; Galliard, C Le; Ma, B; Marchand, D; Maroni, A; Ong, S; Ramstein, B; Rosier, P; Sudol, M; Tomasi-Gustafsson, E; Wiele, J Van de; Boca, G; Braghieri, A; Costanza, S; Genova, P; Lavezzi, L; Montagna, P; Rotondi, A; Abramov, V; Belikov, N; Davidenko, A; Derevschikov, A; Goncharenko, Y; Grishin, V; Kachanov, V; Konstantinov, D; Kormilitsin, V; Melnik, Y; Levin, A; Minaev, N; Mochalov, V; Morozov, D; Nogach, L; Poslavskiy, S; Ryazantsev, A; Ryzhikov, S; Semenov, P; Shein, I; Uzunian, A; Vasiliev, A; Yakutin, A; Bäck, T; Cederwall, B; Makónyi, K; Tegnér, P E; Würtemberg, K M von; Belostotski, S; Gavrilov, G; Itzotov, A; Kashchuk, A; Kisselev, A; Kravchenko, P; Levitskaya, O; Manaenkov, S; Miklukho, O; Naryshkin, Y; Veretennikov, D; Vikhrov, V; Zhadanov, A; Alberto, D; Amoroso, A; Bussa, M P; Busso, L; Mori, F De; Destefanis, M; Fava, L; Ferrero, L; Greco, M; Maggiora, M; Marcello, S; Sosio, S; Spataro, S; Zotti, L; Calvo, D; Coli, S; Remigis, P De; Filippi, A; Giraudo, G; Lusso, S; Mazza, G; Morra, O; Rivetti, A; Wheadon, R; Iazzi, F; Lavagno, A; Younis, H; Birsa, R; Bradamante, F; Bressan, A; Martin, A; Clement, H; Galander, B; Balkestal, L Caldeira; Calén, H; Fransson, K; Johansson, T; Kupsc, A; Marciniewski, P; Thomé, E; Wolke, M; Zlomanczuk, J; Díaz, J; Ortiz, A; Dmowski, K; Korzeniewski, R; Przemyslaw, D; Slowinski, B; Chlopik, A; Guzik, Z; Kosinski, K; Melnychuk, D; Wasilewski, A; Wojciechowski, M; Wronka, S; Wysocka, A; Zwieglinski, B; Bühler, P; Hartman, O; Kienle, P; Marton, J; Suzuki, K; Widmann, E; Zmeskal, J

2012-01-01

This document describes the technical layout and the expected performance of the Straw Tube Tracker (STT), the main tracking detector of the PANDA target spectrometer. The STT encloses a Micro-Vertex-Detector (MVD) for the inner tracking and is followed in beam direction by a set of GEM-stations. The tasks of the STT are the measurement of the particle momentum from the reconstructed trajectory and the measurement of the specific energy-loss for a particle identification. Dedicated simulations with full analysis studies of certain proton-antiproton reactions, identified as being benchmark tests for the whole \\Panda scientific program, have been performed to test the STT layout and performance. The results are presented, and the time lines to construct the STT are described.

A high resolution germanium detector array for hypernuclear studies at PANDA

Energy Technology Data Exchange (ETDEWEB)

Bleser, Sebastian; Sanchez Lorente, Alicia; Steinen, Marcell [Helmholtz-Institut Mainz (Germany); Gerl, Juergen; Kojouharov, Ivan [GSI, Darmstadt (Germany); Iazzi, Felice [Politecnico, Torino, Turin (Italy); INFN, Torino, Turin (Italy); Pochodzalla, Josef; Rittgen, Kai; Sahin, Cihan [Institute for Nuclear Physics, JGU Mainz (Germany); Collaboration: PANDA-Collaboration

2013-07-01

The PANDA experiment, planned at the FAIR facility in Darmstadt, aims at the high resolution γ-spectroscopy of double Λ hypernuclei. For this purpose a devoted detector setup is required, consisting of a primary nuclear target, an active secondary target and a germanium detector array for the γ-spectroscopy. Due to the limited space within the PANDA detector a compact design is required. In particular the conventional LN{sub 2} cooling system must be replaced by an electro-mechanical device and a new arrangement of the crystals is needed. This poster shows the ongoing development of the germanium detectors. Test measurements of a single crystal prototype with an improved cooling concept are shown. Thermal simulations for a triple crystal detector are presented. Aditionally studies of the optimization of the detector arrangement inside the PANDA barrel spectrometer are shown. Finally the status on digital pulse shape analysis is presented which will be necessary to deal with high counting rates and to recover the high original energy resolution in case of neutron damage.

Basic Fibroblast Growth Factor Stimulates the Proliferation of Bone Marrow Mesenchymal Stem Cells in Giant Panda (Ailuropoda melanoleuca).

Science.gov (United States)

Wang, Jun-Jie; Liu, Yu-Liang; Sun, Yuan-Chao; Ge, Wei; Wang, Yong-Yong; Dyce, Paul W; Hou, Rong; Shen, Wei

2015-01-01

It has been widely known that the giant panda (Ailuropoda melanoleuca) is one of the most endangered species in the world. An optimized platform for maintaining the proliferation of giant panda mesenchymal stem cells (MSCs) is very necessary for current giant panda protection strategies. Basic fibroblast growth factor (bFGF), a member of the FGF family, is widely considered as a growth factor and differentiation inducer within the stem cell research field. However, the role of bFGF on promoting the proliferation of MSCs derived from giant panda bone marrow (BM) has not been reported. In this study, we aimed to investigate the role of bFGF on the proliferation of BM-MSCs derived from giant panda. MSCs were cultured for cell proliferation analysis at 24, 48 and 72 hrs following the addition of bFGF. With increasing concentrations of bFGF, cell numbers gradually increased. This was further demonstrated by performing 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide (MTT) cell proliferation assay, 5-Bromo-2-deoxyUridine (BrdU) labeling and cell cycle testing. Furthermore, the percentage of MSCs that were OCT4 positive increased slightly following treatment with 5 ng/ml bFGF. Moreover, we demonstrated that the extracellular signal-regulated kinase (ERK) signaling pathway may play an important role in the proliferation of panda MSCs stimulated by bFGF. In conclusion, this study suggests that giant panda BM-MSCs have a high proliferative capacity with the addition of 5 ng/ml bFGF in vitro.

Basic Fibroblast Growth Factor Stimulates the Proliferation of Bone Marrow Mesenchymal Stem Cells in Giant Panda (Ailuropoda melanoleuca)

Science.gov (United States)

Wang, Jun-Jie; Liu, Yu-Liang; Sun, Yuan-Chao; Ge, Wei; Wang, Yong-Yong; Dyce, Paul W.; Hou, Rong; Shen, Wei

2015-01-01

It has been widely known that the giant panda (Ailuropoda melanoleuca) is one of the most endangered species in the world. An optimized platform for maintaining the proliferation of giant panda mesenchymal stem cells (MSCs) is very necessary for current giant panda protection strategies. Basic fibroblast growth factor (bFGF), a member of the FGF family, is widely considered as a growth factor and differentiation inducer within the stem cell research field. However, the role of bFGF on promoting the proliferation of MSCs derived from giant panda bone marrow (BM) has not been reported. In this study, we aimed to investigate the role of bFGF on the proliferation of BM-MSCs derived from giant panda. MSCs were cultured for cell proliferation analysis at 24, 48 and 72 hrs following the addition of bFGF. With increasing concentrations of bFGF, cell numbers gradually increased. This was further demonstrated by performing 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide (MTT) cell proliferation assay, 5-Bromo-2-deoxyUridine (BrdU) labeling and cell cycle testing. Furthermore, the percentage of MSCs that were OCT4 positive increased slightly following treatment with 5 ng/ml bFGF. Moreover, we demonstrated that the extracellular signal-regulated kinase (ERK) signaling pathway may play an important role in the proliferation of panda MSCs stimulated by bFGF. In conclusion, this study suggests that giant panda BM-MSCs have a high proliferative capacity with the addition of 5 ng/ml bFGF in vitro. PMID:26375397

Basic Fibroblast Growth Factor Stimulates the Proliferation of Bone Marrow Mesenchymal Stem Cells in Giant Panda (Ailuropoda melanoleuca.

Directory of Open Access Journals (Sweden)

Jun-Jie Wang

Full Text Available It has been widely known that the giant panda (Ailuropoda melanoleuca is one of the most endangered species in the world. An optimized platform for maintaining the proliferation of giant panda mesenchymal stem cells (MSCs is very necessary for current giant panda protection strategies. Basic fibroblast growth factor (bFGF, a member of the FGF family, is widely considered as a growth factor and differentiation inducer within the stem cell research field. However, the role of bFGF on promoting the proliferation of MSCs derived from giant panda bone marrow (BM has not been reported. In this study, we aimed to investigate the role of bFGF on the proliferation of BM-MSCs derived from giant panda. MSCs were cultured for cell proliferation analysis at 24, 48 and 72 hrs following the addition of bFGF. With increasing concentrations of bFGF, cell numbers gradually increased. This was further demonstrated by performing 3-(4,5-dimethyl-2-thiazolyl-2,5-diphenyl-2-H-tetrazolium bromide (MTT cell proliferation assay, 5-Bromo-2-deoxyUridine (BrdU labeling and cell cycle testing. Furthermore, the percentage of MSCs that were OCT4 positive increased slightly following treatment with 5 ng/ml bFGF. Moreover, we demonstrated that the extracellular signal-regulated kinase (ERK signaling pathway may play an important role in the proliferation of panda MSCs stimulated by bFGF. In conclusion, this study suggests that giant panda BM-MSCs have a high proliferative capacity with the addition of 5 ng/ml bFGF in vitro.

First complete genome sequence of parainfluenza virus 5 isolated from lesser panda.

Science.gov (United States)

Zhai, Jun-Qiong; Zhai, Shao-Lun; Lin, Tao; Liu, Jian-Kui; Wang, He-Xing; Li, Bing; Zhang, He; Zou, Shu-Zhan; Zhou, Xia; Wu, Meng-Fan; Chen, Wu; Luo, Man-Lin

2017-05-01

Parainfluenza virus 5 (PIV5) is widespread in mammals and humans. Up to now, there is little information about PIV5 infection in lesser pandas. In this study, a PIV5 variant (named ZJQ-221) was isolated from a lesser panda with respiratory disease in Guangzhou zoo in Guangdong province, southern China. The full-length genome of ZJQ-221 was found to be 15,246 nucleotides and consisted of seven non-overlapping genes encoding eight proteins (i.e., NP, V, P, M, F, SH, HN and L). Sequence alignment and genetic analysis revealed that ZJQ-221 shared a close relationship with a PIV5 strain of canine-origin (1168-1) from South Korea. The findings of this study confirm the presence of PIV5 in lesser panda and indicate this mammal as a possible natural reservoir. Furthermore they highlight the urgent need to strengthen viral surveillance and control of PIV5 in zoo animals.

Python for data analysis data wrangling with Pandas, NumPy, and IPython

CERN Document Server

McKinney, Wes

2017-01-01

Get complete instructions for manipulating, processing, cleaning, and crunching datasets in Python. Updated for Python 3.6, the second edition of this hands-on guide is packed with practical case studies that show you how to solve a broad set of data analysis problems effectively. You’ll learn the latest versions of pandas, NumPy, IPython, and Jupyter in the process. Written by Wes McKinney, the creator of the Python pandas project, this book is a practical, modern introduction to data science tools in Python. It’s ideal for analysts new to Python and for Python programmers new to data science and scientific computing. Data files and related material are available on GitHub. Use the IPython shell and Jupyter notebook for exploratory computing Learn basic and advanced features in NumPy (Numerical Python) Get started with data analysis tools in the pandas library Use flexible tools to load, clean, transform, merge, and reshape data Create informative visualizations with matplotlib ...

El método de soporte Paideia en el hospital: la experiencia del Hospital de Clínicas de la Universidade Estadual de Campinas (HC-Unicamp

Directory of Open Access Journals (Sweden)

Adriano Massuda

2010-01-01

Full Text Available Esta investigación analiza los cambios que se produjeron en un hospital universitario, en el que se utilizó como referencial el método de soporte Paideia. La experiencia se realizó en el marco de un curso de especialización en gestión hospitalaria ofrecido por el Departamento de Medicina Preventiva y Social y por la dirección del Hospital de Clínicas de la Universidade Estadual de Campinas (HC-Unicamp a personal de las áreas de docencia, asistencia y administración, y a coordinadores de servicios del hospital. Los resultados fueron analizados por triangulación de técnicas. Se observaron cambios en las prácticas de gestión, de atención y en la relación con el Sistema Único de Salud (SUS, especialmente en el primer aspecto. Se infiere que los cambios fueron influenciados tanto por el proyecto de la dirección del hospital, como por las actividades del curso. Se concluye que el método potenció y amplió el espectro de cambios en el hospital, en función de la perspectiva política y pedagógica de crear redes dialógicas en colectivos organizados, haciendo uso de un abordaje metodológico dialéctico problematizador de la praxis, con ofertas teórico-conceptuales aportadas por el soporte externo. Sin embargo, fue posible identificar límites en la aplicación del método en el hospital, originados, principalmente, en aspectos políticos, ideológicos, culturales y organizacionales.

Post-test analysis of PANDA test P4

International Nuclear Information System (INIS)

Hart, J.; Woudstra, A.; Koning, H.

1999-01-01

The results of a post-test analysis of the integral system test P4, which has been executed in the PANDA facility at PSI in Switzerland within the framework of Work Package 2 of the TEPSS project are presented. The post-test analysis comprises an evaluation of the PANDA test P4 and a comparison of the test results with the results of simulations using the RELAPS/MOD3.2, TRAC-BF1, and MELCOR 1.8.4 codes. The PANDA test P4 has provided data about how trapped air released from the drywell later in the transient affects PCCS performance in an adequate manner. The well-defined measurements can serve as an important database for the assessment of thermal hydraulic system analysis codes, especially for conditions that could be met in passively operated advanced reactors, i.e. low pressure and small driving forces. Based on the analysis of the test data, the test acceptance criteria have been met. The test P4 has been successfully completed and the instrument readings were with the permitted ranges. The PCCs showed a favorable and robust performance and a wide margin for decay heat removal from the containment. The PANDA P4 test demonstrated that trapped air, released from the drywell later in the transient, only temporarily and only slightly affected the performance of the passive containment cooling system. The analysis of the results of the RELAPS code showed that the overall behaviour of the test has been calculated quite well with regards to pressure, mass flow rates, and pool boil-down. This accounts both for the pre-test and the post-test simulations. However, due to the one-dimensional, stacked-volume modeling of the PANDA DW, WW, and GDCS vessels, 3D-effects such as in-vessel mixing and recirculation could not be calculated. The post-test MELCOR simulation showed an overall behaviour that is comparable to RELAPS. However, MELCOR calculated almost no air trapping in the PCC tubes that could hinder the steam condensation rate. This resulted in lower calculated

Feasibility studies of time-like proton electromagnetic form factors at PANDA at FAIR

CERN Document Server

Singh, B.; Krusche, B.; Steinacher, M.; Walford, N.; Liu, B.; Liu, H.; Liu, Z.; Shen, X.; Wang, C.; Zhao, J.; Albrecht, M.; Erlen, T.; Fink, M.; Heinsius, F.; Held, T.; Holtmann, T.; Jasper, S.; Keshk, I.; Koch, H.; Kopf, B.; Kuhlmann, M.; Kümmel, M.; Leiber, S.; Mikirtychyants, M.; Musiol, P.; Mustafa, A.; Pelizäus, M.; Pychy, J.; Richter, M.; Schnier, C.; Schröder, T.; Sowa, C.; Steinke, M.; Triffterer, T.; Wiedner, U.; Ball, M.; Beck, R.; Hammann, C.; Ketzer, B.; Kube, M.; Mahlberg, P.; Rossbach, M.; Schmidt, C.; Schmitz, R.; Thoma, U.; Urban, M.; Walther, D.; Wendel, C.; Wilson, A.; Bianconi, A.; Bragadireanu, M.; Caprini, M.; Pantea, D.; Patel, B.; Czyzycki, W.; Domagala, M.; Filo, G.; Jaworowski, J.; Krawczyk, M.; Lisowski, F.; Lisowski, E.; Michałek, M.; Poznański, P.; Płażek, J.; Korcyl, K.; Kozela, A.; Kulessa, P.; Lebiedowicz, P.; Pysz, K.; Schäfer, W.; Szczurek, A.; Fiutowski, T.; Idzik, M.; Mindur, B.; Przyborowski, D.; Swientek, K.; Biernat, J.; Kamys, B.; Kistryn, S.; Korcyl, G.; Krzemien, W.; Magiera, A.; Moskal, P.; Pyszniak, A.; Rudy, Z.; Salabura, P.; Smyrski, J.; Strzempek, P.; Wronska, A.; Augustin, I.; Böhm, R.; Lehmann, I.; Marinescu, D. Nicmorus; Schmitt, L.; Varentsov, V.; Al-Turany, M.; Belias, A.; Deppe, H.; Dzhygadlo, R.; Ehret, A.; Flemming, H.; Gerhardt, A.; Götzen, K.; Gromliuk, A.; Gruber, L.; Karabowicz, R.; Kliemt, R.; Krebs, M.; Kurilla, U.; Lehmann, D.; Löchner, S.; Lühning, J.; Lynen, U.; Orth, H.; Patsyuk, M.; Peters, K.; Saito, T.; Schepers, G.; Schmidt, C.J.; Schwarz, C.; Schwiening, J.; Täschner, A.; Traxler, M.; Ugur, C.; Voss, B.; Wieczorek, P.; Wilms, A.; Zühlsdorf, M.; Abazov, V.; Alexeev, G.; Arefiev, V.A.; Astakhov, V.; Barabanov, M. Yu.; Batyunya, B.V.; Davydov, Y.; Dodokhov, V. Kh.; Efremov, A.; Fechtchenko, A.; Fedunov, A.G.; Galoyan, A.; Grigoryan, S.; Koshurnikov, E.K.; Lobanov, Y. Yu.; Lobanov, V.I.; Makarov, A.F.; Malinina, L.V.; Malyshev, V.; Olshevskiy, A.G.; Perevalova, E.; Piskun, A.A.; Pocheptsov, T.; Pontecorvo, G.; Rodionov, V.; Rogov, Y.; Salmin, R.; Samartsev, A.; Sapozhnikov, M.G.; Shabratova, G.; Skachkov, N.B.; Skachkova, A.N.; Strokovsky, E.A.; Suleimanov, M.; Teshev, R.; Tokmenin, V.; Uzhinsky, V.; Vodopianov, A.; Zaporozhets, S.A.; Zhuravlev, N.I.; Zorin, A.G.; Branford, D.; Glazier, D.; Watts, D.; Böhm, M.; Britting, A.; Eyrich, W.; Lehmann, A.; Pfaffinger, M.; Uhlig, F.; Dobbs, S.; Seth, K.; Tomaradze, A.; Xiao, T.; Bettoni, D.; Carassiti, V.; Cotta Ramusino, A.; Dalpiaz, P.; Drago, A.; Fioravanti, E.; Garzia, I.; Savrie, M.; Akishina, V.; Kisel, I.; Kozlov, G.; Pugach, M.; Zyzak, M.; Gianotti, P.; Guaraldo, C.; Lucherini, V.; Bersani, A.; Bracco, G.; Macri, M.; Parodi, R.F.; Biguenko, K.; Brinkmann, K.; Di Pietro, V.; Diehl, S.; Dormenev, V.; Drexler, P.; Düren, M.; Etzelmüller, E.; Galuska, M.; Gutz, E.; Hahn, C.; Hayrapetyan, A.; Kesselkaul, M.; Kühn, W.; Kuske, T.; Lange, J.S.; Liang, Y.; Metag, V.; Nanova, M.; Nazarenko, S.; Novotny, R.; Quagli, T.; Reiter, S.; Rieke, J.; Rosenbaum, C.; Schmidt, M.; Schnell, R.; Stenzel, H.; Thöring, U.; Ullrich, M.; Wagner, M.N.; Wasem, T.; Wohlfahrt, B.; Zaunick, H.; Ireland, D.; Rosner, G.; Seitz, B.; Deepak, P.N.; Kulkarni, A.; Apostolou, A.; Babai, M.; Kavatsyuk, M.; Lemmens, P.J.; Lindemulder, M.; Loehner, H.; Messchendorp, J.; Schakel, P.; Smit, H.; Tiemens, M.; van der Weele, J.C.; Veenstra, R.; Vejdani, S.; Dutta, K.; Kalita, K.; Kumar, A.; Roy, A.; Sohlbach, H.; Bai, M.; Bianchi, L.; Büscher, M.; Cao, L.; Cebulla, A.; Dosdall, R.; Gillitzer, A.; Goldenbaum, F.; Grunwald, D.; Herten, A.; Hu, Q.; Kemmerling, G.; Kleines, H.; Lehrach, A.; Nellen, R.; Ohm, H.; Orfanitski, S.; Prasuhn, D.; Prencipe, E.; Pütz, J.; Ritman, J.; Schadmand, S.; Sefzick, T.; Serdyuk, V.; Sterzenbach, G.; Stockmanns, T.; Wintz, P.; Wüstner, P.; Xu, H.; Zambanini, A.; Li, S.; Li, Z.; Sun, Z.; Rigato, V.; Isaksson, L.; Achenbach, P.; Corell, O.; Denig, A.; Distler, M.; Hoek, M.; Karavdina, A.; Lauth, W.; Merkel, H.; Müller, U.; Pochodzalla, J.; Sanchez, S.; Schlimme, S.; Sfienti, C.; Thiel, M.; Ahmadi, H.; Ahmed, S.; Bleser, S.; Capozza, L.; Cardinali, M.; Dbeyssi, A.; Deiseroth, M.; Feldbauer, F.; Fritsch, M.; Fröhlich, B.; Jasinski, P.; Kang, D.; Khaneft, D.; Klasen, R.; Leithoff, H.H.; Lin, D.; Maas, F.; Maldaner, S.; Marta, M.; Michel, M.; Espí, M. C. Mora; Morales Morales, C.; Motzko, C.; Nerling, F.; Noll, O.; Pflüger, S.; Pitka, A.; Piñeiro, D. Rodríguez; Sanchez-Lorente, A.; Steinen, M.; Valente, R.; Weber, T.; Zambrana, M.; Zimmermann, I.; Fedorov, A.; Korjik, M.; Missevitch, O.; Boukharov, A.; Malyshev, O.; Marishev, I.; Balanutsa, V.; Balanutsa, P.; Chernetsky, V.; Demekhin, A.; Dolgolenko, A.; Fedorets, P.; Gerasimov, A.; Goryachev, V.; Chandratre, V.; Datar, V.; Dutta, D.; Jha, V.; Kumawat, H.; Mohanty, A.K.; Parmar, A.; Roy, B.; Sonika, G.; Fritzsch, C.; Grieser, S.; Hergemöller, A.; Hetz, B.; Hüsken, N.; Khoukaz, A.; Wessels, J.P.; Khosonthongkee, K.; Kobdaj, C.; Limphirat, A.; Srisawad, P.; Yan, Y.; Barnyakov, M.; Barnyakov, A. Yu.; Beloborodov, K.; Blinov, A.E.; Blinov, V.E.; Bobrovnikov, V.S.; Kononov, S.; Kravchenko, E.A.; Kuyanov, I.A.; Martin, K.; Onuchin, A.P.; Serednyakov, S.; Sokolov, A.; Tikhonov, Y.; Atomssa, E.; Kunne, R.; Marchand, D.; Ramstein, B.; van de Wiele, J.; Wang, Y.; Boca, G.; Costanza, S.; Genova, P.; Montagna, P.; Rotondi, A.; Abramov, V.; Belikov, N.; Bukreeva, S.; Davidenko, A.; Derevschikov, A.; Goncharenko, Y.; Grishin, V.; Kachanov, V.; Kormilitsin, V.; Levin, A.; Melnik, Y.; Minaev, N.; Mochalov, V.; Morozov, D.; Nogach, L.; Poslavskiy, S.; Ryazantsev, A.; Ryzhikov, S.; Semenov, P.; Shein, I.; Uzunian, A.; Vasiliev, A.; Yakutin, A.; Tomasi-Gustafsson, E.; Roy, U.; Yabsley, B.; Belostotski, S.; Gavrilov, G.; Izotov, A.; Manaenkov, S.; Miklukho, O.; Veretennikov, D.; Zhdanov, A.; Makonyi, K.; Preston, M.; Tegner, P.; Wölbing, D.; Bäck, T.; Cederwall, B.; Rai, A.K.; Godre, S.; Calvo, D.; Coli, S.; De Remigis, P.; Filippi, A.; Giraudo, G.; Lusso, S.; Mazza, G.; Mignone, M.; Rivetti, A.; Wheadon, R.; Balestra, F.; Iazzi, F.; Introzzi, R.; Lavagno, A.; Olave, J.; Amoroso, A.; Bussa, M.P.; Busso, L.; De Mori, F.; Destefanis, M.; Fava, L.; Ferrero, L.; Greco, M.; Hu, J.; Lavezzi, L.; Maggiora, M.; Maniscalco, G.; Marcello, S.; Sosio, S.; Spataro, S.; Birsa, R.; Bradamante, F.; Bressan, A.; Martin, A.; Calen, H.; Andersson, W. Ikegami; Johansson, T.; Kupsc, A.; Marciniewski, P.; Papenbrock, M.; Pettersson, J.; Schönning, K.; Wolke, M.; Galnander, B.; Diaz, J.; Chackara, V. Pothodi; Chlopik, A.; Kesik, G.; Melnychuk, D.; Slowinski, B.; Trzcinski, A.; Wojciechowski, M.; Wronka, S.; Zwieglinski, B.; Bühler, P.; Marton, J.; Steinschaden, D.; Suzuki, K.; Widmann, E.; Zmeskal, J.

2016-01-01

The results of simulations for future measurements of electromagnetic form factors at \\PANDA (FAIR) within the PandaRoot software framework are reported. The statistical precision at which the proton form factors can be determined is estimated. The signal channel $\\bar p p \\to e^+ e^-$ is studied on the basis of two different but consistent procedures. The suppression of the main background channel, i.e. the $\\bar p p \\to \\pi^+ \\pi^-$, is studied. Furthermore, the background versus signal efficiency, statistic and systematic uncertainties on the extracted proton form factors are evaluated using to the two different procedures. The results are consistent with those of a previous simulation study using an older, simplified framework. However, a slightly better precision is achieved in the PandaRoot study in a large range of momentum transfer, assuming the nominal beam condition and detector performances.

Giant panda (Ailuropoda melanoleuca) sperm morphometry and function after repeated freezing and thawing.

Science.gov (United States)

Santiago-Moreno, J; Esteso, M C; Pradiee, J; Castaño, C; Toledano-Díaz, A; O'Brien, E; Lopez-Sebastián, A; Martínez-Nevado, E; Delclaux, M; Fernández-Morán, J; Zhihe, Z

2016-05-01

This work examines the effects of subsequent cycles of freezing-thawing on giant panda (Ailuropoda melanoleuca) sperm morphometry and function, and assesses whether density-gradient centrifugation (DGC) can increase the number of freezing-thawing cycles this sperm can withstand. A sperm sample was collected by electroejaculation from a mature giant panda and subjected to five freezing-thawing cycles. Although repeated freezing-thawing negatively affected (P 60% of the sperm cells in both treatments showed acrosome integrity even after the fifth freezing cycle. In fresh semen, the sperm head length was 4.7 μm, the head width 3.6 μm, area 14.3 μm(2) and perimeter length 14.1 μm. The present results suggest that giant panda sperm trends to be resistant to repeated freezing-thawing, even without DGC selection. © 2015 Blackwell Verlag GmbH.

Feasibility studies of time-like proton electromagnetic form factors at PANDA at FAIR

Energy Technology Data Exchange (ETDEWEB)

Singh, B. [Aligarth Muslim Univ., Aligarth (India). Physics Dept.; Erni, W.; Krusche, B. [Basel Univ. (Switzerland); Collaboration: The PANDA Collaboration; and others

2016-10-15

Simulation results for future measurements of electromagnetic proton form factors at PANDA(FAIR) within the PandaRoot software framework are reported. The statistical precision with which the proton form factors can be determined is estimated. The signal channel anti pp → e{sup +}e{sup -} is studied on the basis of two different but consistent procedures. The suppression of the main background channel, i.e. anti pp → π{sup +}π{sup -}, is studied. Furthermore, the background versus signal efficiency, statistical and systematical uncertainties on the extracted proton form factors are evaluated using two different procedures. The results are consistent with those of a previous simulation study using an older, simplified framework. However, a slightly better precision is achieved in the PandaRoot study in a large range of momentum transfer, assuming the nominal beam conditions and detector performance. (orig.)

Feasibility studies of time-like proton electromagnetic form factors at PANDA at FAIR

International Nuclear Information System (INIS)

Singh, B.

2016-01-01

Simulation results for future measurements of electromagnetic proton form factors at PANDA(FAIR) within the PandaRoot software framework are reported. The statistical precision with which the proton form factors can be determined is estimated. The signal channel anti pp → e + e - is studied on the basis of two different but consistent procedures. The suppression of the main background channel, i.e. anti pp → π + π - , is studied. Furthermore, the background versus signal efficiency, statistical and systematical uncertainties on the extracted proton form factors are evaluated using two different procedures. The results are consistent with those of a previous simulation study using an older, simplified framework. However, a slightly better precision is achieved in the PandaRoot study in a large range of momentum transfer, assuming the nominal beam conditions and detector performance. (orig.)

Repeatable Reverse Engineering with PANDA

Science.gov (United States)

2015-12-08

necessary layout information for the Android 2.3 and 4.2 SDK kernels. See Section IV-C for an example of the kind of deep reverse engineering of Android apps ...code re-use and simplifying complex analysis development. We demonstrate PANDA’s effectiveness via a number of use cases, including enabling an old but...continue to function. 2) Identify critical vulnerabilities . 3) Understand the true purpose and actions of code. It is common for legacy code to stop

Diet and nutrient balance of red panda in Nepal

Science.gov (United States)

Panthi, Saroj; Coogan, Sean C. P.; Aryal, Achyut; Raubenheimer, David

2015-10-01

We identified the winter plant species consumed by red panda in the Dhorpatan Hunting Reserve of eastern Nepal and compared this to the early-summer diet which was determined previously by Panthi et al. (2012). In addition, we estimated the proximate nutritional content of the leaves identified in red panda diet for both seasons, and we used nutritional geometry to explore macronutrient balance of leaves from the two different sampling periods. We identified six different plants in winter scats, which were the same as found in the previously determined early-summer diet. Arundinaria spp. bamboos were the main species found (82.1 % relative frequency), followed by Acer spp. (6.3 %), Betula utilis (4.6 %), Quercus semicarpifolia (3.7 %), Berberis spp. (1.3 %), and lichens (1.0 %), leaving 2.0 % unidentified. Geometric analysis suggested that the macronutrient balance of seasonal diets were similar in nutrient balance to the most frequently consumed Arundinaria spp. Differences in macronutrient balance may indicate seasonal nutrient preferences, such as increased carbohydrate intake in winter for thermogenesis, and increased protein and lipid intake in early summer to support reproduction and lactation; however, these differences may also indicate differences in resource availability. Habitat conserved for red panda in the region should include sufficient Arundinaria spp. as well as lesser consumed plants which may serve as complimentary foods.

Impact of the genfit2 Kalman-filter-based algorithms on physics simulations performed with PandaRoot

Energy Technology Data Exchange (ETDEWEB)

Prencipe, Elisabetta; Ritman, James [Forschungszentrum Juelich, IKP1, Juelich (Germany); Collaboration: PANDA-Collaboration

2016-07-01

PANDA is a planned experiment at FAIR (Darmstadt) with a cooled antiproton beam in a range [1.5;15] GeV/c, allowing a wide physics program in nuclear and particle physics. It is the only experiment worldwide, which combines a solenoid field (B=2 T) and a dipole field (B=2 Tm) in an experiment with a fixed target topology, in that energy regime. The tracking system of PANDA involves the presence of a high performance silicon vertex detector, a GEM detector, a Straw-Tubes central tracker, a forward tracking system, and a luminosity monitor. The offline tracking algorithm is developed within the PandaRoot framework, which is a part of the FAIRRoot project. The algorithm here presented is based on a tool containing the Kalman Filter equations and a deterministic annealing filter (genfit). The Kalman-Filter-based algorithms have a wide range of applications; among those in particle physics they can perform extrapolations of track parameters and covariance matrices. The impact on physics simulations performed for the PANDA experiment is shown for the first time, with the PandaRoot framework: improvement is shown for those channels where a good low momentum tracking is required (p{sub T}<400 MeV/c), i.e. D mesons and Λ reconstruction, of about a factor 2.

Feature-extraction algorithms for the PANDA electromagnetic calorimeter

NARCIS (Netherlands)

Kavatsyuk, M.; Guliyev, E.; Lemmens, P. J. J.; Loehner, H.; Poelman, T. P.; Tambave, G.; Yu, B

2009-01-01

The feature-extraction algorithms are discussed which have been developed for the digital front-end electronics of the electromagnetic calorimeter of the PANDA detector at the future FAIR facility. Performance parameters have been derived in test measurements with cosmic rays, particle and photon

Palo Verde nuclear dynamic analysis (PANDA)

International Nuclear Information System (INIS)

Girjashankar, P.V.; Secker, P.A. Jr.; LeClair, S.J.; Mendoza, J.; Webb, J.R.

1988-01-01

Arizona Nuclear Power Project (ANPP) has initiated the development of a large scale dynamic analysis computer program for the Palo Verde Nuclear Generating Station (PVNGS). This paper presents the decision processes and preliminary development activities that have been pursued related to the code development. The PANDA (Palo Verde Nuclear Dynamic Analysis) code will be used for a variety of applications as described in this paper

Efectos del Estrés Laboral y los Mecanismos de Afrontamiento en el Personal de Salud del Área Quirúrgica del Hospital IESS Riobamba

OpenAIRE

Yuquilema Guachilema, Zoila del Rocio

2015-01-01

El presente trabajo se orientó a la determinación de los efectos del estrés laboral y los mecanismos de afrontamiento en el personal del área quirúrgica del Hospital IESS Riobamba. La población se conformó con 30 profesionales de la salud que laboran en el área quirúrgica: enfermeras, auxiliares de enfermería, asistentes de anestesiología y anestesiólogos. La información se obtuvo por medio de encuestas. Los resultados de la investigación demuestran que los causales de estrés laboral son: e...

Tests and developments of the PANDA Endcap Disc DIRC

International Nuclear Information System (INIS)

Etzelmüller, E.; Belias, A.; Dzhygadlo, R.; Gerhardt, A.; Götzen, K.; Kalicy, G.; Krebs, M.; Lehmann, D.; Nerling, F.; Patsyuk, M.; Peters, K.; Schepers, G.; Schmitt, L.; Schwarz, C.; Schwiening, J.; Traxler, M.; Zühlsdorf, M.; Britting, A.; Eyrich, W.; Lehmann, A.

2016-01-01

The PANDA experiment at the future Facility for Antiproton and Ion Research (FAIR) requires excellent particle identification. Two different DIRC detectors will utilize internally reflected Cherenkov light of charged particles to enable the separation of pions and kaons up to momenta of 4 GeV/c. The Endcap Disc DIRC will be placed in the forward endcap of PANDA's central spectrometer covering polar angles between 5° and 22°. Its final design is based on MCP-PMTs for the photon detection and an optical system made of fused silica. A new prototype has been investigated during a test beam at CERN in May 2015 and first results will be presented. In addition a new synthetic fused silica material by Nikon has been tested and was found to be radiation hard.

Memorias de las desapariciones. Los vecinos del Centro Clandestino de Detención del Hospital Posadas, Buenos Aires, Argentina

Directory of Open Access Journals (Sweden)

Emilio Crenzel

2012-10-01

Full Text Available En este artículo se examinan las memorias que circulan entre vecinos del Hospital Posadas, ubicado en Haedo, provincia de Buenos Aires, Argentina, sobre la represión política en tiempos de la última dictadura militar (1976‑1983. Tras el golpe de Estado, funcionó en el Hospital Posadas un Centro Clandestino de Detención en el cual se mantenían personas cautivas ilegalmente, en condición de desaparecidas. Así, en el Hospital Posadas convivieron, simultáneamente, las prácticas relativas al cuidado y restauración de la salud y la perpetración de torturas y asesinatos. En este trabajo se analizarán los recuerdos y olvidos de estos hechos entre diversos vecinos que habitaban, en tiempos de la dictadura, en las inmediaciones del Hospital Posadas. Específicamente, se indagará qué experiencias tuvieron con la violencia de Estado, en particular con el sistema de desaparición de personas, y cómo ellas han quedado inscriptas en sus memorias personales. Por último, se analizarán la información que circulaba y los grados de conocimiento que poseían estos vecinos sobre los atributos, naturaleza y responsables de las desapariciones en el hospital mientras éstas se perpetraban.

Adoption, Cynical Detachment, and New Age Beliefs in Juno and Kung Fu Panda

OpenAIRE

Chen, Fu-jen

2017-01-01

In his article "Adoption, Cynical Detachment, and New Age Beliefs in Juno and Kung Fu Panda" Fu-Jen Chen situates his study within today's prevailing climate of global consumption to argue that the 2007 film Juno—featuring an unconventional portrayal of the adoption triad and a cynical detachment from public values—not only trivializes and depoliticizes the practice of adoption but also serves as an ideological supplement to today's global capitalism. Furthermore, Kung Fu Panda 1 & 2 (2008; 2...

Annotation: PANDAS--A Model for Human Autoimmune Disease

Science.gov (United States)

Swedo, Susan E.; Grant, Paul J.

2005-01-01

Background: Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcus infections (PANDAS) is a recently recognized syndrome in which pre-adolescent children have abrupt onsets of tics and/or obsessive-compulsive symptoms, a recurring and remitting course of illness temporally related to streptococcal infections, and associated…

Hopes and challenges for giant panda conservation under climate change in the Qinling Mountains of China.

Science.gov (United States)

Gong, Minghao; Guan, Tianpei; Hou, Meng; Liu, Gang; Zhou, Tianyuan

2017-01-01

One way that climate change will impact animal distributions is by altering habitat suitability and habitat fragmentation. Understanding the impacts of climate change on currently threatened species is of immediate importance because complex conservation planning will be required. Here, we mapped changes to the distribution, suitability, and fragmentation of giant panda habitat under climate change and quantified the direction and elevation of habitat shift and fragmentation patterns. These data were used to develop a series of new conservation strategies for the giant panda. Qinling Mountains, Shaanxi, China. Data from the most recent giant panda census, habitat factors, anthropogenic disturbance, climate variables, and climate predictions for the year 2050 (averaged across four general circulation models) were used to project giant panda habitat in Maxent. Differences in habitat patches were compared between now and 2050. While climate change will cause a 9.1% increase in suitable habitat and 9% reduction in subsuitable habitat by 2050, no significant net variation in the proportion of suitable and subsuitable habitat was found. However, a distinct climate change-induced habitat shift of 11 km eastward by 2050 is predicted firstly. Climate change will reduce the fragmentation of suitable habitat at high elevations and exacerbate the fragmentation of subsuitable habitat below 1,900 m above sea level. Reduced fragmentation at higher elevations and worsening fragmentation at lower elevations have the potential to cause overcrowding of giant pandas at higher altitudes, further exacerbating habitat shortage in the central Qinling Mountains. The habitat shift to the east due to climate change may provide new areas for giant pandas but poses severe challenges for future conservation.

Analysis of the cytochrome c oxidase subunit 1 (COX1) gene reveals the unique evolution of the giant panda.

Science.gov (United States)

Hu, Yao-Dong; Pang, Hui-Zhong; Li, De-Sheng; Ling, Shan-Shan; Lan, Dan; Wang, Ye; Zhu, Yun; Li, Di-Yan; Wei, Rong-Ping; Zhang, He-Min; Wang, Cheng-Dong

2016-11-05

As the rate-limiting enzyme of the mitochondrial respiratory chain, cytochrome c oxidase (COX) plays a crucial role in biological metabolism. "Living fossil" giant panda (Ailuropoda melanoleuca) is well-known for its special bamboo diet. In an effort to explore functional variation of COX1 in the energy metabolism behind giant panda's low-energy bamboo diet, we looked at genetic variation of COX1 gene in giant panda, and tested for its selection effect. In 1545 base pairs of the gene from 15 samples, 9 positions were variable and 1 mutation leaded to an amino acid sequence change. COX1 gene produces six haplotypes, nucleotide (pi), haplotype diversity (Hd). In addition, the average number of nucleotide differences (k) is 0.001629±0.001036, 0.8083±0.0694 and 2.517, respectively. Also, dN/dS ratio is significantly below 1. These results indicated that giant panda had a low population genetic diversity, and an obvious purifying selection of the COX1 gene which reduces synthesis of ATP determines giant panda's low-energy bamboo diet. Phylogenetic trees based on the COX1 gene were constructed to demonstrate that giant panda is the sister group of other Ursidae. Copyright © 2016 Elsevier B.V. All rights reserved.

Italian version of the Parkinson Neuropsychometric Dementia Assessment (PANDA): a useful instrument to detect cognitive impairments in Parkinson's Disease.

Science.gov (United States)

Pignatti, Riccardo; Bertella, Laura; Scarpina, Federica; Mauro, Alessandro; Portolani, Elisa; Calabrese, Pasquale

2014-01-01

Parkinson's disease (PD) is frequently characterized by cognitive and affective dysfunctions. The "Parkinson Neuropsychometric Dementia Assessment" (PANDA) is a screening tool designed for the early detection of mild cognitive impairment as well as dementia in PD. The PANDA is already validated in German and in French. The aim of the present work was to provide normative data for the Italian-speaking population, Swiss regions included; moreover, the effectiveness of the PANDA compared to the Mini Mental State Examination (MMSE) was tested. One-hundred and eleven PD patients with and without cognitive impairment and one-hundred and three matched healthy subjects participated at this study; all patients underwent an extensive neuropsychological evaluation. A PANDA total score of 13 appeared to be the most fitting cut-off with a sensitivity of 96.6% and a specificity of 82.2%; with the MMSE, the same value of sensitivity but with a specificity of 72,4% was reached only by adopting a cut-off of 28. Moreover, a PANDA range of 13-17 appeared to be suggestive for possible cognitive disturbance. The present work provides evidence for the effectiveness of the PANDA in evaluating cognitive deficits also in PD Italian-speaking patients, even when their pathological degree is still initial or very mild.

Construction of a 7-fold BAC library and cytogenetic mapping of 10 genes in the giant panda (Ailuropoda melanoleuca

Directory of Open Access Journals (Sweden)

Zhang Ying

2006-11-01

Full Text Available Abstract Background The giant panda, one of the most primitive carnivores, is an endangered animal. Although it has been the subject of many interesting studies during recent years, little is known about its genome. In order to promote research on this genome, a bacterial artificial chromosome (BAC library of the giant panda was constructed in this study. Results This BAC library contains 198,844 clones with an average insert size of 108 kb, which represents approximately seven equivalents of the giant panda haploid genome. Screening the library with 15 genes and 8 microsatellite markers demonstrates that it is representative and has good genome coverage. Furthermore, ten BAC clones harbouring AGXT, GHR, FSHR, IRBP, SOX14, TTR, BDNF, NT-4, LH and ZFX1 were mapped to 8 pairs of giant panda chromosomes by fluorescence in situ hybridization (FISH. Conclusion This is the first large-insert genomic DNA library for the giant panda, and will contribute to understanding this endangered species in the areas of genome sequencing, physical mapping, gene cloning and comparative genomic studies. We also identified the physical locations of ten genes on their relative chromosomes by FISH, providing a preliminary framework for further development of a high resolution cytogenetic map of the giant panda.

Structure of the power consumption in hospitals: case of the IMSS development in Aguascalientes; Estructura del consumo energetico en hospitales: caso del conjunto del IMSS en Aguascalientes

Energy Technology Data Exchange (ETDEWEB)

Herrera Garcia, Antonio [HGZ No. 1 del IMSS en Aguascalientes (Mexico); Morillon Galvez, David [Instituto de Ingenieria de la UNAM (Mexico)

2003-07-01

The hospitals, since they operate 24 hours a day during 365 days per year, are great consumers of energy. They consume up to 75% of fuels for their transformation in thermal energy. Consequently it is important to study and determine the structure of the power consumption in hospitals. In the present work with the study case of the Instituto Mexicano del Seguro Social (IMSS) development in Aguascalientes, Mexico a pattern of power consumption and the distribution of annual consumption of electricity and diesel oil from 1993 to 2001 is obtained. It is observed in the study case, that with the work of the engineering equipment of conservation they managed themselves to reduce to the annual consumption of diesel oil and electricity with economic savings greater than 1'200,000 of 1999 pesos. [Spanish] Los hospitales, como trabajan 24 al dia los 365 dias del ano, son grandes consumidores de energia. Ellos consumen hasta el 75% de combustibles para su transformacion en energia termica. En consecuencia es importante estudiar y determinar la estructura del consumo energetico en hospitales. En el presente trabajo con el estudio de caso del conjunto del Instituto Mexicano del Seguro Social (IMSS) en Aguascalientes, Mexico se obtiene el patron de consumo energetico y la distribucion de consumo anual de electricidad y diesel de l993 a 2001. Se observa en el caso de estudio, que con el trabajo del equipo de ingenieros de conservacion se lograron reducir los consumos anuales de diesel y electricidad con ahorros economicos mayores a 1,200,000 pesos de 1999.

Large anthropogenic impacts on a charismatic small carnivore: Insights from distribution surveys of red panda Ailurus fulgens in Nepal.

Science.gov (United States)

Panthi, Saroj; Khanal, Gopal; Acharya, Krishna Prasad; Aryal, Achyut; Srivathsa, Arjun

2017-01-01

Protected areas are key to preserving biodiversity and maintaining ecosystem services. However, their ability to ensure long-term survival of threatened andendangered species varies across countries, regions and landscapes. Distribution surveys can beparticularly important for assessing the value of protected areas, and gauging their efficacy incatering to species-specific requirements. We assessed the conservation value of one such reserve for a charismatic yet globally endangered species, the red panda Ailurus fulgens,in the light of on-going land-use transformation in Nepal. We conducted field surveys forindirect signs of red pandas along forest trails in 25-km2 sampling grid cells (n = 54) of Dhorpatan Hunting Reserve, and confronted a set of ecological hypotheses to the data using hierarchical occupancy models. We estimated overall occupancy at Ψ(SE) = 0.41 (0.007), with relatively high site-level detectability [p = 0.93 (SE = 0.001)]. Our results show that despitebeing a subsistence form of small-scale resource use, extraction of bamboo and livestock grazing negatively affected panda occurrence, albeit at different intensities. The amount of bamboo cover,rather than the overall proportion of forest cover, had greater influence on the panda occurrence. Despite availability of bamboo cover, areas with bamboo extraction and anthropogenic disturbances were less likely to be occupied by pandas. Together, these results suggest that long-term persistence of red pandas in this reserve and elsewhere across the species' range will require preventing commercial extractionof bamboo, coupled with case-specific regulation of anthropogenic exploitation of red panda habitats.

Fecal near infrared spectroscopy to discriminate physiological status in giant pandas.

Directory of Open Access Journals (Sweden)

Erin E Wiedower

Full Text Available Giant panda (Ailuropoda melanoleuca monitoring and research often require accurate estimates of population size and density. However, obtaining these estimates has been challenging. Innovative technologies, such as fecal near infrared reflectance spectroscopy (FNIRS, may be used to differentiate between sex, age class, and reproductive status as has been shown for several other species. The objective of this study was to determine if FNIRS could be similarly used for giant panda physiological discriminations. Based on samples from captive animals in four U.S. zoos, FNIRS calibrations correctly identified 78% of samples from adult males, 81% from adult females, 85% from adults, 89% from juveniles, 75% from pregnant and 70% from non-pregnant females. However, diet had an impact on the success of the calibrations. When diet was controlled for plant part such that "leaf only" feces were evaluated, FNIRS calibrations correctly identified 93% of samples from adult males and 95% from adult females. These data show that FNIRS has the potential to differentiate between the sex, age class, and reproductive status in the giant panda and may be applicable for surveying wild populations.

Sustainable harvest, people and pandas: assessing a decade of managed wild harvest and trade in Schisandra sphenanthera.

Science.gov (United States)

Brinckmann, J A; Luo, W; Xu, Q; He, X; Wu, J; Cunningham, A B

2018-06-05

Endemic to China, the distribution of Schisandra sphenanthera Rehder & E.H.Wilson includes giant panda (Ailuropoda melanoleuca David, 1869) habitats in forests of the Minshan and Qinling Mountains, both inside and outside conservation areas. The fruit is used in indigenous medicines of the Qiang, Tibetan and Yi ethnic minorities of Sichuan. Also used in traditional Chinese medicine (TCM), indications for use are prescribed in the Chinese Pharmacopoeia. For continued access and medical use, survival of healthy populations depends on forests. Biodiversity conservation programmes implemented in forests within the panda landscapes that also benefit rural and indigenous communities, link future access to wild medicinal plants with survival of the panda and resilient rural economies. This study aimed at assessing the project activities, institutional-level outcomes and achievements, 10 years on, of the 5-year (2007-2011) UNDP- and WWF- supported EU-China Biodiversity Programme for sustainable, "panda-friendly" schisandra. Our study combined analysis of quantitative data such as purchase records coupled with qualitative data obtained from field work, project documents, site-visit reports, certification documents and published articles about the project. At start of project, interested companies were identified to support economic viability of the sustainable wild harvesting and a "panda friendly" pro-conservation model that provided an incentive to maintain habitat outside formal protected areas. Criteria of relevant sustainability standards, the Organic Wild-crop Harvesting Practice Standard and FairWild Standard, were applied while a new standard was drafted, the Giant Panda Friendly Products Standard. The initial pilot project involving 1 village determined feasibility leading to formation of the Pingwu Shuijing TCM Cooperative which, by 2016, scaled out to membership of 22 villages. From the cooperative's first commercial sale of S. sphenanthera Rehder & E

How do two giant panda populations adapt to their habitats in the Qinling and Qionglai Mountains, China

NARCIS (Netherlands)

Liu, Xiaoji; Wang, Tiejun; Wang, Ting; Skidmore, A.K.; Songer, M.

2015-01-01

The spatial separation of the Qinling Mountains from the western mountains has caused morphological and genetic distinctions of giant pandas. Could this separation also cause the pandas’ behavior change? In this research, we focused on the pandas’ movement pattern and selected two wild panda groups

Transcriptome-Derived Tetranucleotide Microsatellites and Their Associated Genes from the Giant Panda (Ailuropoda melanoleuca).

Science.gov (United States)

Song, Xuhao; Shen, Fujun; Huang, Jie; Huang, Yan; Du, Lianming; Wang, Chengdong; Fan, Zhenxin; Hou, Rong; Yue, Bisong; Zhang, Xiuyue

2016-09-01

Recently, an increasing number of microsatellites or simple sequence repeats (SSRs) have been found and characterized from transcriptomes. Such SSRs can be employed as putative functional markers to easily tag corresponding genes, which play an important role in biomedical studies and genetic analysis. However, the transcriptome-derived SSRs for giant panda (Ailuropoda melanoleuca) are not yet available. In this work, we identified and characterized 20 tetranucleotide microsatellite loci from a transcript database generated from the blood of giant panda. Furthermore, we assigned their predicted transcriptome locations: 16 loci were assigned to untranslated regions (UTRs) and 4 loci were assigned to coding regions (CDSs). Gene identities of 14 transcripts contained corresponding microsatellites were determined, which provide useful information to study the potential contribution of SSRs to gene regulation in giant panda. The polymorphic information content (PIC) values ranged from 0.293 to 0.789 with an average of 0.603 for the 16 UTRs-derived SSRs. Interestingly, 4 CDS-derived microsatellites developed in our study were also polymorphic, and the instability of these 4 CDS-derived SSRs was further validated by re-genotyping and sequencing. The genes containing these 4 CDS-derived SSRs were embedded with various types of repeat motifs. The interaction of all the length-changing SSRs might provide a way against coding region frameshift caused by microsatellite instability. We hope these newly gene-associated biomarkers will pave the way for genetic and biomedical studies for giant panda in the future. In sum, this set of transcriptome-derived markers complements the genetic resources available for giant panda. © The American Genetic Association. 2016. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Low major histocompatibility complex class II DQA diversity in the Giant Panda (Ailuropoda melanoleuca

Directory of Open Access Journals (Sweden)

Ruan Xiang-Dong

2007-06-01

Full Text Available Abstract Background The giant panda (Ailuropoda melanoleuca is one of the most endangered animals due to habitat fragmentation and loss. Although the captive breeding program for this species is now nearly two decades old, researches on the genetic background of such captive populations, especially on adaptive molecular polymorphism of major histocompatibility complex (MHC, are still limited. In this study, we characterized adaptive variation of the giant panda's MHC DQA gene by PCR amplification of its antigen-recognizing region (i.e. the exon 2 and subsequent single-strand conformational polymorphism (SSCP and sequence analyses. Results The results revealed a low level of DQA exon 2 diversity in this rare animal, presenting 6 alleles from 61 giant panda individuals. The observed polymorphism was restricted to 9 amino acid substitutions, all of which occurred at and adjacent to positions forming the functionally important antigen-binding sites. All the samples were in Hardy-Weinberg proportions. A significantly higher rate of non-synonymous than synonymous substitutions at the antigen-binding sites indicated positive selection for diversity in the locus. Conclusion The DQA allelic diversity of giant pandas was low relative to other vertebrates. Nonetheless, the pandas exhibited more alleles in DQA than those in DRB, suggesting the alpha chain genes would play a leading role when coping with certain pathogens and thus should be included in conservation genetic investigation. The microsatellite and MHC loci might predict long-term persistence potential and short-term survival ability, respectively. Consequently, it is recommended to utilize multiple suites of microsatellite markers and multiple MHC loci to detect overall genetic variation in order to design unbiased conservation strategies.

Prevalence of intestinal parasitic infections in free-ranging Red Panda Ailurus fulgens Cuvier, 1825 (Mammalia: Carnivora: Ailuridae in Nepal

Directory of Open Access Journals (Sweden)

Sonam Tashi Lama

2015-06-01

Full Text Available The Red Panda Ailurus fulgens is a small carnivore that is adapted to a mainly herbivorous diet.  The present study was conducted to investigate the prevalence of parasitic infections in a free-ranging population of Red Pandas in a community forest in Nepal.  A total of 23 faecal samples were collected and examined.  Protozoa infections were the most common and cestode infections occurred the least.  Our findings suggest that parasites might be a significant problem for the health of the Red Pandas in the study area.  Molecular methods should be used to further investigate the taxonomic position of the parasites and their role in threatening the resilience of Red Panda populations in Nepal.  

Quantifying the evidence for co-benefits between species conservation and climate change mitigation in giant panda habitats.

Science.gov (United States)

Li, Renqiang; Xu, Ming; Powers, Ryan; Zhao, Fen; Jetz, Walter; Wen, Hui; Sheng, Qingkai

2017-10-05

Conservationists strive for practical, cost-effective management solutions to forest-based species conservation and climate change mitigation. However, this is compromised by insufficient information about the effectiveness of protected areas in increasing carbon storage, and the co-benefits of species and carbon conservation remain poorly understood. Here, we present the first rigorous quantitative assessment of the roles of giant panda nature reserves (NRs) in carbon sequestration, and explore the co-benefits of habitat conservation and climate change mitigation. Results show that more than 90% of the studied panda NRs are effective in increasing carbon storage, with the mean biomass carbon density of the whole NRs exhibiting a 4.2% higher growth rate compared with lands not declared as NRs over the period 1988-2012, while this effectiveness in carbon storage masks important patterns of spatial heterogeneity across the giant panda habitats. Moreover, the significant associations have been identified between biomass carbon density and panda's habitat suitability in ~85% NRs and at the NR level. These findings suggest that the planning for carbon and species conservation co-benefits would enhance the greatest return on limited conservation investments, which is a critical need for the giant panda after its conservation status has been downgraded from "endangered" to "vulnerable".

The PASTA chip - A free-running readout ASIC for silicon strip sensors in PANDA

Energy Technology Data Exchange (ETDEWEB)

Goerres, Andre; Stockmanns, Tobias; Ritman, James [Institut fuer Kernphysik, Forschungszentrum Juelich, Juelich (Germany); Rivetti, Angelo [INFN Sezione di Torino, Torino (Italy); Collaboration: PANDA-Collaboration

2014-07-01

The PANDA experiment is a multi purpose detector, investigating hadron physics in the charm quark mass regime. It is one of the main experiments at the future FAIR accelerator facility, using pp annihilations from a 1.5-15 GeV/c anti-proton beam. Because of the broad physics spectrum and the similarity of event and background signals, PANDA does not rely on a hardware-level trigger decision. The innermost of PANDA's sub-systems is the Micro Vertex Detector (MVD), consisting of silicon pixel and strip sensors. The latter will be read out by a specialized, free-running readout front-end called PANDA Strip ASIC (PASTA). It has to face a high event rate of up to 40 kHz/ch in an radiation-intense environment. To fulfill the MVD's requirements, it has to give accurate timing information to incoming events (<10 ns) and determine the collected charge with an 8-bit precision. The design has to meet cooling and placing restrictions, leading to a very low power consumption (<4 mW/ch) and limited dimensions. Therefore, a simple, time-based readout approach is chosen. In this talk, the conceptual design of the front-end is presented.

Thoracic limb morphology of the red panda (Ailurus fulgens evidenced by osteology and radiography

Directory of Open Access Journals (Sweden)

Modesta Makungu

2015-07-01

Full Text Available The red panda (Ailurus fulgens is distributed primarily in the Himalayas and southern China. It is classified as a vulnerable species by the International Union for Conservation of Nature. The aim of this study was to describe the normal osteology and radiographic anatomy of the thoracic limb of the red panda. Radiography of the right thoracic limb was performed in seven captive adult red pandas. Radiographic findings were correlated with bone specimens from three adult animals. The scapula was wide craniocaudally and presented with a large area for the origin of the teres major muscle. The square-shaped major tubercle did not extend proximal to the head of the humerus. The medial epicondyle was prominent. A supracondylar foramen was present. The radial tuberosity and sesamoid bone for the abductor digiti I longus were prominent. The accessory carpal bone was directed palmarolaterally. Metacarpal bones were widely spread. The thoracic limb morphology of the red panda evidenced by osteology and radiography indicated flexibility of the thoracic limb joints and well-developed flexor and supinator muscles, which are important in arboreal quadrupedal locomotion. Knowledge gained during this study may prove useful in identifying skeletal material or remains and diagnosing musculoskeletal diseases and injuries of the thoracic limb.

Thoracic limb morphology of the red panda (Ailurus fulgens) evidenced by osteology and radiography.

Science.gov (United States)

Makungu, Modesta; Groenewald, Hermanus B; du Plessis, Wencke M; Barrows, Michelle; Koeppel, Katja N

2015-07-15

The red panda (Ailurus fulgens) is distributed primarily in the Himalayas and southern China. It is classified as a vulnerable species by the International Union for Conservation of Nature. The aim of this study was to describe the normal osteology and radiographic anatomy of the thoracic limb of the red panda. Radiography of the right thoracic limb was performed in seven captive adult red pandas. Radiographic findings were correlated with bone specimens from three adult animals. The scapula was wide craniocaudally and presented with a large area for the origin of the teres major muscle. The square-shaped major tubercle did not extend proximal to the head of the humerus. The medial epicondyle was prominent. A supracondylar foramen was present. The radial tuberosity and sesamoid bone for the abductor digiti I longus were prominent. The accessory carpal bone was directed palmarolaterally. Metacarpal bones were widely spread. The thoracic limb morphology of the red panda evidenced by osteology and radiography indicated flexibility of the thoracic limb joints and well-developed flexor and supinator muscles, which are important in arboreal quadrupedal locomotion. Knowledge gained during this study may prove useful in identifying skeletal material or remains and diagnosing musculoskeletal diseases and injuries of the thoracic limb.

Outbreak and genotyping of canine distemper virus in captive Siberian tigers and red pandas.

Science.gov (United States)

Zhang, He; Shan, Fen; Zhou, Xia; Li, Bing; Zhai, Jun-Qiong; Zou, Shu-Zhan; Wu, Meng-Fan; Chen, Wu; Zhai, Shao-Lun; Luo, Man-Lin

2017-08-15

In this study, four canine distemper virus (CDV) strains were isolated from captive Siberian tigers (Panthera tigris altaica) and red pandas (Ailurus fulgens) during two separate CDV outbreaks in a zoo in Guangdong province, China. Sequence alignment and phylogenetic analyses based on the full-length hemagglutinin (H) and fusion (F) genes showed that they were closely identical to genotype Asia-1. Prior to confirmation of CDV in Siberian tigers, to control spread of the disease, a live attenuated combination CDV vaccine was used among almost all carnivore animals except for red pandas in which another recombinant combination CDV vaccine was used. However, about two months later, CDV re-emerged and caused the death among red pandas. Based on the vaccination records, the live combination vaccine could be considered an ideal weapon against CDV in zoo carnivore animals. Although the recombinant combination CDV vaccine was safe for red pandas, its protection effectiveness remains to be further investigated. Moreover, according to the outbreak interval time and sequence characterization, we suspected that stray cats circulating in the zoo were the intermediate host, which contributed to CDV spread from stray dogs to zoo animals. This study revealed the importance of vaccination and biosecurity for zoo animals.

Ennekuulmatud loomalaulud / Panda Bear (Noah Lennox) ; interv. Siim Nestor

Index Scriptorium Estoniae

Panda Bear (Noah Lennox)

2006-01-01

Intervjuu eksperimentaalset popmuusikat viljeleva ameerika ansambli Animal Collective laulja Panda Bear'iga (kontsert 4. juulil Tallinnas Lillepaviljonis). Heliplaatidest: "Spirit They're Gone, Spirit They've Vanished", "Danse Manatee", "Hollindagain", "Campfire Songs", "Here Comes the Indian", "Sung Tongs", "Feels"

EXPERIENCIAS PSICOSEXUALES DE PACIENTES HISTERECTOMIZADAS DEL SERVICIO DE GINECOLOGÍA DEL HOSPITAL REGIONAL DOCENTE LAS MERCEDES – CHICLAYO 2013

OpenAIRE

Núñez Manayay, Tania Mercedes; Universidad Señor de Sipán; Vera Ñañez, Huendy Jame; Universidad Señor de Sipán

2014-01-01

 La presente investigación cualitativa titulada Experiencias psicosexuales de pacientes histerectomizadas del servicio de Ginecología del Hospital Regional Docente las Mercedes – Chiclayo 2013 tuvo como objetivo describir las experiencias psicosexuales de pacientes histerectomizadas. Con diseño estudio de caso; la muestra conformada por siete pacientes post histerectomizadas de seis meses a un año; en la recolección de datos se utilizó la observación y la entrevista semiestructurada, las que ...

Ús dels recursos web per part dels hospitals americans en la promoció de l'alimentació saludable

OpenAIRE

Gordó Rosell, Roser

2010-01-01

Revisió de l'ús que fan els centres hospitalaris americans dels recursos que ofereix Internet, amb l'objectiu de promoure l'alimentació saludable entre la població. Revisión del uso que hacen los centros hospitalarios americanos de los recursos que ofrece Internet, con el objetivo de promover la alimentación saludable entre la población. Review of the use made by American hospitals of Internet resources with the aim of promoting healthy eating habits among the population.

Feasibility studies of time-like proton electromagnetic form factors at overlinePANDA at FAIR

Science.gov (United States)

Singh, B.; Erni, W.; Krusche, B.; Steinacher, M.; Walford, N.; Liu, B.; Liu, H.; Liu, Z.; Shen, X.; Wang, C.; Zhao, J.; Albrecht, M.; Erlen, T.; Fink, M.; Heinsius, F.; Held, T.; Holtmann, T.; Jasper, S.; Keshk, I.; Koch, H.; Kopf, B.; Kuhlmann, M.; Kümmel, M.; Leiber, S.; Mikirtychyants, M.; Musiol, P.; Mustafa, A.; Pelizäus, M.; Pychy, J.; Richter, M.; Schnier, C.; Schröder, T.; Sowa, C.; Steinke, M.; Triffterer, T.; Wiedner, U.; Ball, M.; Beck, R.; Hammann, C.; Ketzer, B.; Kube, M.; Mahlberg, P.; Rossbach, M.; Schmidt, C.; Schmitz, R.; Thoma, U.; Urban, M.; Walther, D.; Wendel, C.; Wilson, A.; Bianconi, A.; Bragadireanu, M.; Caprini, M.; Pantea, D.; Patel, B.; Czyzycki, W.; Domagala, M.; Filo, G.; Jaworowski, J.; Krawczyk, M.; Lisowski, F.; Lisowski, E.; Michałek, M.; Poznański, P.; Płażek, J.; Korcyl, K.; Kozela, A.; Kulessa, P.; Lebiedowicz, P.; Pysz, K.; Schäfer, W.; Szczurek, A.; Fiutowski, T.; Idzik, M.; Mindur, B.; Przyborowski, D.; Swientek, K.; Biernat, J.; Kamys, B.; Kistryn, S.; Korcyl, G.; Krzemien, W.; Magiera, A.; Moskal, P.; Pyszniak, A.; Rudy, Z.; Salabura, P.; Smyrski, J.; Strzempek, P.; Wronska, A.; Augustin, I.; Böhm, R.; Lehmann, I.; Nicmorus Marinescu, D.; Schmitt, L.; Varentsov, V.; Al-Turany, M.; Belias, A.; Deppe, H.; Dzhygadlo, R.; Ehret, A.; Flemming, H.; Gerhardt, A.; Götzen, K.; Gromliuk, A.; Gruber, L.; Karabowicz, R.; Kliemt, R.; Krebs, M.; Kurilla, U.; Lehmann, D.; Löchner, S.; Lühning, J.; Lynen, U.; Orth, H.; Patsyuk, M.; Peters, K.; Saito, T.; Schepers, G.; Schmidt, C. J.; Schwarz, C.; Schwiening, J.; Täschner, A.; Traxler, M.; Ugur, C.; Voss, B.; Wieczorek, P.; Wilms, A.; Zühlsdorf, M.; Abazov, V.; Alexeev, G.; Arefiev, V. A.; Astakhov, V.; Barabanov, M. Yu.; Batyunya, B. V.; Davydov, Y.; Dodokhov, V. Kh.; Efremov, A.; Fechtchenko, A.; Fedunov, A. G.; Galoyan, A.; Grigoryan, S.; Koshurnikov, E. K.; Lobanov, Y. Yu.; Lobanov, V. I.; Makarov, A. F.; Malinina, L. V.; Malyshev, V.; Olshevskiy, A. G.; Perevalova, E.; Piskun, A. A.; Pocheptsov, T.; Pontecorvo, G.; Rodionov, V.; Rogov, Y.; Salmin, R.; Samartsev, A.; Sapozhnikov, M. G.; Shabratova, G.; Skachkov, N. B.; Skachkova, A. N.; Strokovsky, E. A.; Suleimanov, M.; Teshev, R.; Tokmenin, V.; Uzhinsky, V.; Vodopianov, A.; Zaporozhets, S. A.; Zhuravlev, N. I.; Zorin, A. G.; Branford, D.; Glazier, D.; Watts, D.; Böhm, M.; Britting, A.; Eyrich, W.; Lehmann, A.; Pfaffinger, M.; Uhlig, F.; Dobbs, S.; Seth, K.; Tomaradze, A.; Xiao, T.; Bettoni, D.; Carassiti, V.; Cotta Ramusino, A.; Dalpiaz, P.; Drago, A.; Fioravanti, E.; Garzia, I.; Savrie, M.; Akishina, V.; Kisel, I.; Kozlov, G.; Pugach, M.; Zyzak, M.; Gianotti, P.; Guaraldo, C.; Lucherini, V.; Bersani, A.; Bracco, G.; Macri, M.; Parodi, R. F.; Biguenko, K.; Brinkmann, K.; Di Pietro, V.; Diehl, S.; Dormenev, V.; Drexler, P.; Düren, M.; Etzelmüller, E.; Galuska, M.; Gutz, E.; Hahn, C.; Hayrapetyan, A.; Kesselkaul, M.; Kühn, W.; Kuske, T.; Lange, J. S.; Liang, Y.; Metag, V.; Nanova, M.; Nazarenko, S.; Novotny, R.; Quagli, T.; Reiter, S.; Rieke, J.; Rosenbaum, C.; Schmidt, M.; Schnell, R.; Stenzel, H.; Thöring, U.; Ullrich, M.; Wagner, M. N.; Wasem, T.; Wohlfahrt, B.; Zaunick, H.; Ireland, D.; Rosner, G.; Seitz, B.; Deepak, P. N.; Kulkarni, A.; Apostolou, A.; Babai, M.; Kavatsyuk, M.; Lemmens, P. J.; Lindemulder, M.; Loehner, H.; Messchendorp, J.; Schakel, P.; Smit, H.; Tiemens, M.; van der Weele, J. C.; Veenstra, R.; Vejdani, S.; Dutta, K.; Kalita, K.; Kumar, A.; Roy, A.; Sohlbach, H.; Bai, M.; Bianchi, L.; Büscher, M.; Cao, L.; Cebulla, A.; Dosdall, R.; Gillitzer, A.; Goldenbaum, F.; Grunwald, D.; Herten, A.; Hu, Q.; Kemmerling, G.; Kleines, H.; Lehrach, A.; Nellen, R.; Ohm, H.; Orfanitski, S.; Prasuhn, D.; Prencipe, E.; Pütz, J.; Ritman, J.; Schadmand, S.; Sefzick, T.; Serdyuk, V.; Sterzenbach, G.; Stockmanns, T.; Wintz, P.; Wüstner, P.; Xu, H.; Zambanini, A.; Li, S.; Li, Z.; Sun, Z.; Xu, H.; Rigato, V.; Isaksson, L.; Achenbach, P.; Corell, O.; Denig, A.; Distler, M.; Hoek, M.; Karavdina, A.; Lauth, W.; Liu, Z.; Merkel, H.; Müller, U.; Pochodzalla, J.; Sanchez, S.; Schlimme, S.; Sfienti, C.; Thiel, M.; Ahmadi, H.; Ahmed, S.; Bleser, S.; Capozza, L.; Cardinali, M.; Dbeyssi, A.; Deiseroth, M.; Feldbauer, F.; Fritsch, M.; Fröhlich, B.; Jasinski, P.; Kang, D.; Khaneft, D.; Klasen, R.; Leithoff, H. H.; Lin, D.; Maas, F.; Maldaner, S.; Martínez, M.; Michel, M.; Mora Espí, M. C.; Morales Morales, C.; Motzko, C.; Nerling, F.; Noll, O.; Pflüger, S.; Pitka, A.; Rodríguez Piñeiro, D.; Sanchez-Lorente, A.; Steinen, M.; Valente, R.; Weber, T.; Zambrana, M.; Zimmermann, I.; Fedorov, A.; Korjik, M.; Missevitch, O.; Boukharov, A.; Malyshev, O.; Marishev, I.; Balanutsa, V.; Balanutsa, P.; Chernetsky, V.; Demekhin, A.; Dolgolenko, A.; Fedorets, P.; Gerasimov, A.; Goryachev, V.; Chandratre, V.; Datar, V.; Dutta, D.; Jha, V.; Kumawat, H.; Mohanty, A. K.; Parmar, A.; Roy, B.; Sonika, G.; Fritzsch, C.; Grieser, S.; Hergemöller, A.; Hetz, B.; Hüsken, N.; Khoukaz, A.; Wessels, J. P.; Khosonthongkee, K.; Kobdaj, C.; Limphirat, A.; Srisawad, P.; Yan, Y.; Barnyakov, M.; Barnyakov, A. Yu.; Beloborodov, K.; Blinov, A. E.; Blinov, V. E.; Bobrovnikov, V. S.; Kononov, S.; Kravchenko, E. A.; Kuyanov, I. A.; Martin, K.; Onuchin, A. P.; Serednyakov, S.; Sokolov, A.; Tikhonov, Y.; Atomssa, E.; Kunne, R.; Marchand, D.; Ramstein, B.; van de Wiele, J.; Wang, Y.; Boca, G.; Costanza, S.; Genova, P.; Montagna, P.; Rotondi, A.; Abramov, V.; Belikov, N.; Bukreeva, S.; Davidenko, A.; Derevschikov, A.; Goncharenko, Y.; Grishin, V.; Kachanov, V.; Kormilitsin, V.; Levin, A.; Melnik, Y.; Minaev, N.; Mochalov, V.; Morozov, D.; Nogach, L.; Poslavskiy, S.; Ryazantsev, A.; Ryzhikov, S.; Semenov, P.; Shein, I.; Uzunian, A.; Vasiliev, A.; Yakutin, A.; Tomasi-Gustafsson, E.; Roy, U.; Yabsley, B.; Belostotski, S.; Gavrilov, G.; Izotov, A.; Manaenkov, S.; Miklukho, O.; Veretennikov, D.; Zhdanov, A.; Makonyi, K.; Preston, M.; Tegner, P.; Wölbing, D.; Bäck, T.; Cederwall, B.; Rai, A. K.; Godre, S.; Calvo, D.; Coli, S.; De Remigis, P.; Filippi, A.; Giraudo, G.; Lusso, S.; Mazza, G.; Mignone, M.; Rivetti, A.; Wheadon, R.; Balestra, F.; Iazzi, F.; Introzzi, R.; Lavagno, A.; Olave, J.; Amoroso, A.; Bussa, M. P.; Busso, L.; De Mori, F.; Destefanis, M.; Fava, L.; Ferrero, L.; Greco, M.; Hu, J.; Lavezzi, L.; Maggiora, M.; Maniscalco, G.; Marcello, S.; Sosio, S.; Spataro, S.; Birsa, R.; Bradamante, F.; Bressan, A.; Martin, A.; Calen, H.; Ikegami Andersson, W.; Johansson, T.; Kupsc, A.; Marciniewski, P.; Papenbrock, M.; Pettersson, J.; Schönning, K.; Wolke, M.; Galnander, B.; Diaz, J.; Pothodi Chackara, V.; Chlopik, A.; Kesik, G.; Melnychuk, D.; Slowinski, B.; Trzcinski, A.; Wojciechowski, M.; Wronka, S.; Zwieglinski, B.; Bühler, P.; Marton, J.; Steinschaden, D.; Suzuki, K.; Widmann, E.; Zmeskal, J.

2016-10-01

Simulation results for future measurements of electromagnetic proton form factors at overlinePANDA (FAIR) within the PandaRoot software framework are reported. The statistical precision with which the proton form factors can be determined is estimated. The signal channel bar{p}p→ e+e- is studied on the basis of two different but consistent procedures. The suppression of the main background channel, i.e. bar{p}p→ π+π-, is studied. Furthermore, the background versus signal efficiency, statistical and systematical uncertainties on the extracted proton form factors are evaluated using two different procedures. The results are consistent with those of a previous simulation study using an older, simplified framework. However, a slightly better precision is achieved in the PandaRoot study in a large range of momentum transfer, assuming the nominal beam conditions and detector performance.

Feasibility study of a transversely polarized target in PANDA

Energy Technology Data Exchange (ETDEWEB)

Ahmadi, Heybat; Deiseroth, Malte; Khaneft, Dmitry; Noll, Oliver; Valente, Roserio; Zambrana, Manuel [Helmholtz-Institut Mainz (Germany); Johannes Gutenberg-Universitaet Mainz (Germany); Ahmed, Samer [Helmholtz-Institut Mainz (Germany); Capozza, Luigi; Dbeyssi, Alaa; Froehlich, Bertold; Lin, Dexu; Maas, Frank; Mora Espi, Maria Carmen; Morales Morales, Cristina; Rodriguez Pineiro, David; Zimmermann, Iris [Helmholtz-Institut Mainz (Germany); GSI Helmholtzzentrum fuer Schwerionenforschung GmbH (Germany)

2015-07-01

The PANDA (Antiproton Annihilation at Darmstadt) spectrometer, located at the Facility for Antiproton and Ion Research (FAIR), is an excellent tool for exploring the nucleon structure. An unpolarized target allows the determination of the electromagnetic time-like form factor of the proton. An additional experiment in which the target is transversely polarized is necessary for the first-time extraction of their imaginary part. A transverse polarization requires the shielding of the 2 T longitudinal field from the PANDA-Solenoid at the target volume and an additional transverse holding field. We present results from our first experiment at the Institut fuer Kernphysik in Mainz on intense magnetic flux shielding using a BSCCO (bismuth strontium calcium copper oxide) thin-wall hollow cylinder at 4.2 K and a 1.4 T external magnetic field and compare this to numerical calculations.

The primary target for the hypernuclear experiment at PANDA

Energy Technology Data Exchange (ETDEWEB)

Bleser, Sebastian; Martinez Rojo, Marta; Sanchez Lorente, Alicia; Steinen, Marcell [Helmholtz-Institut Mainz (Germany); Iazzi, Felice [INFN, Torino (Italy); Politecnico di Torino (Italy); Pochodzalla, Josef [Helmholtz-Institut Mainz (Germany); Institut fuer Kernphysik, JGU Mainz (Germany); Rausch, Nicolas [Institut fuer Kernphysik, JGU Mainz (Germany); Collaboration: PANDA-Collaboration

2016-07-01

A key aspect of the PANDA experiment at the future FAIR facility is the production and spectroscopy of ΛΛ hypernuclei. The double hypernuclei are produced in a two-stage target system consisting of a primary in-beam filament to produce low momentum Ξ{sup -} hyperons which are stopped and converted into two Λ hyperons in a secondary external target. A system of piezo motors will be used to steer the primary target in two dimensions. This allows to achieve a constant luminosity by adjusting the position and provides the replacement of eventually broken target wires. The poster shows the mechanical integration of this system within the vacuum chamber attached to the beampipe. Its motion is controlled using the EPICS framework as planned for PANDA. In addition the results of radiation tests with foreseen target wires are presented.

FPGA based compute nodes for high level triggering in PANDA

International Nuclear Information System (INIS)

Kuehn, W; Gilardi, C; Kirschner, D; Lang, J; Lange, S; Liu, M; Perez, T; Yang, S; Schmitt, L; Jin, D; Li, L; Liu, Z; Lu, Y; Wang, Q; Wei, S; Xu, H; Zhao, D; Korcyl, K; Otwinowski, J T; Salabura, P

2008-01-01

PANDA is a new universal detector for antiproton physics at the HESR facility at FAIR/GSI. The PANDA data acquisition system has to handle interaction rates of the order of 10 7 /s and data rates of several 100 Gb/s. FPGA based compute nodes with multi-Gb/s bandwidth capability using the ATCA architecture are designed to handle tasks such as event building, feature extraction and high level trigger processing. Data connectivity is provided via optical links as well as multiple Gb Ethernet ports. The boards will support trigger algorithms such us pattern recognition for RICH detectors, EM shower analysis, fast tracking algorithms and global event characterization. Besides VHDL, high level C-like hardware description languages will be considered to implement the firmware

The PASTA chip for the silicon micro strip sensor of the PANDA MVD

Energy Technology Data Exchange (ETDEWEB)

Riccardi, Alberto; Brinkmann, Kai-Thomas; Di Pietro, Valentino; Quagli, Tommaso; Schnell, Robert; Zaunick, Hans-Georg [II. Physikalisches Institut, Justus-Liebig-Universitaet, Giessen (Germany); Ritman, James; Stockmanns, Tobias; Zambanini, Andre [Forschungszentrum Juelich (Germany); Rivetti, Angelo; Rolo, Manuel [INFN Sezione di Torino (Italy); Collaboration: PANDA-Collaboration

2016-07-01

In the Micro Vertex Detector, which is the innermost detector of PANDA, there are two different types of sensors: hybrid pixel and double sided micro strips. My work is focused on the development of the ASIC readout for the strips, which in the PANDA experiment must cope with a hit rate up to 50 kHz per channel. The energy loss measurement of the particles crossing the silicon sensor is obtained by implementing the Time over Threshold technique. The first PASTA (PANDA Strip ASIC) prototype is based on a Time to Digital Converter with an analog clock interpolator which combines good time resolution with a low power consumption. A full size chip was developed in a 0.11μ m CMOS technology and delivered in Autumn 2015. It features 64 channels with both analog and digital parts, a digital global controller, LVDS drivers and integrated bias. In the presentation, an overview of PASTA and the results of the first tests is presented.

Simulation and reconstruction of photon patterns in the PANDA 3D Disc DIRC

International Nuclear Information System (INIS)

Merle, O; Düren, M; Föhl, K; Hayrapetyan, A; Koch, P; Kreutzfeldt, K; Kröck, B; Sporleder, M; Stöckmann, N; Zühlsdorf, M

2012-01-01

The PANDA Disc DIRC is a novel type of Cherenkov detector, being developed to improve the charged particle identification of the upcoming PANDA experiment at the future FAIR facility. The detector has to cover the endcap region of the target spectrometer, resulting in a geometry that by now has never been applied to a DIRC detector. Additional complications are implied by tight space constraints at the foreseen position, interaction rates of 20 MHz up to 50 MHz and the experiments trigger-less readout scheme. To cope with the lack of experience, the development of detector concepts is driven by the development of computer simulations and dedicated reconstruction methods. The performance analysis of a preceding detector concept, presented at the DIRC workshop in 2009, showed several weaknesses which have been eliminated by revising the detector design. This publication summarizes the current status of the software, the reconstruction method and resulting detector performance of the improved design: the PANDA 3D Disc DIRC.

Influence of the distribution of noncondensibles on passive containment condenser performance in PANDA

International Nuclear Information System (INIS)

Bandurski, T.; Huggenberger, M.; Dreier, J.; Aubert, C.; Putz, F.; Gamble, R.E.; Yadigaroglu, G.

2001-01-01

Recently, passive cooling systems have been designed for the long-term decay heat removal from the containment of Advanced Light Water Reactors. In particular, the long-term LOCA response of the Passive Containment Cooling System (PCCS) for the General Electric European Simplified Boiling Water Reactor (ESBWR) has been tested in the large scale PANDA facility. The PANDA tests achieved the dual objective of improving confidence in the performance of the passive heat removal mechanisms underlying the design of the tested systems and extending the data base available for containment analysis code qualification. The tests conducted subject the PCCS to a variety of conditions representing design-basis and beyond-design-basis accident conditions. These include operation in the presence of both heavier and lighter than steam noncondensible gases as well as a variety of asymmetric conditions and challenging start-up conditions. The present paper addresses the transient distribution of noncondensibles and their effect on the passive condenser performance in PANDA

Influence of the distribution of noncondensibles on passive containment condenser performance in PANDA

Energy Technology Data Exchange (ETDEWEB)

Bandurski, T. E-mail: thomas.bandurski@psi.ch; Huggenberger, M.; Dreier, J.; Aubert, C.; Putz, F.; Gamble, R.E. E-mail: robert.gamble@gene.ge.com; Yadigaroglu, G. E-mail: yadigaroglu@iet.mavt.ethz.ch

2001-02-01

Recently, passive cooling systems have been designed for the long-term decay heat removal from the containment of Advanced Light Water Reactors. In particular, the long-term LOCA response of the Passive Containment Cooling System (PCCS) for the General Electric European Simplified Boiling Water Reactor (ESBWR) has been tested in the large scale PANDA facility. The PANDA tests achieved the dual objective of improving confidence in the performance of the passive heat removal mechanisms underlying the design of the tested systems and extending the data base available for containment analysis code qualification. The tests conducted subject the PCCS to a variety of conditions representing design-basis and beyond-design-basis accident conditions. These include operation in the presence of both heavier and lighter than steam noncondensible gases as well as a variety of asymmetric conditions and challenging start-up conditions. The present paper addresses the transient distribution of noncondensibles and their effect on the passive condenser performance in PANDA.

Application of low-enthalpy geothermal energy in the New Hospital of Mollet del Valles; Aplicacion de la geotermia de baja entalpia en el nuevo Hospital de Mollet del Valles

Energy Technology Data Exchange (ETDEWEB)

Cuesta Garcia, M. A.; Mayoral Fernandez, G. R.

2009-07-01

The new Hospital in the city of Mollet del Valles has chosen Geothermic energy for heating and cooling. The installation, built between year 2007 to 2009, will turn the hospital into one of the most sustainable building of Spain because will supply more than 1 MW of heating and cooling peak load with Goethermic energy. Now, this project is the biggest in Spain and it is one of the five biggest in all Europe. (Author)

The barrel and disc DIRC counters for the PANDA experiment at FAIR

Energy Technology Data Exchange (ETDEWEB)

Schmidt, Mustafa [II. Physikalisches Institut, Universitaet Giessen (Germany); Collaboration: PANDA-Collaboration

2016-07-01

The PANDA spectrometer for the future FAIR facility at GSI will be used to address open questions in hadronic physics by investigating antiproton collisions with a fixed target in the momentum range between 1.5 GeV/c and 15 GeV/c. In order to achieve a particle identification with a high precision, two different DIRC detector concepts have been developed by PANDA, which allow a compact detector design together with an excellent performance to cleanly separate pions, kaons, and protons. The Barrel DIRC in the target spectrometer of PANDA is based on the successful BaBar DIRC with several key improvements. It is designed for polar angles between θ = 22 and θ = 140 and momenta up to 3.5 GeV/c. The Disc DIRC is part of the endcap region of the spectrometer and covers the angular range from θ = 5 /10 to θ = 22 in the forward direction of PANDA. It will provide a π/K separation with a 4-σ separation power up to a momentum of 4 GeV/c. Both Cherenkov detectors will use MCP-PMTs for the photon detection in combination with fast readout electronics. The radiators are synthetic fused silica plates with precision polished surfaces that guarantee to have very little photon losses by total reflection and conserve the Cherenkov angle during propagation through the optical system. Simulations with Geant4 and tests with several prototypes at various test beam facilities have been used to evaluate the designs and validate the expected PID performance of the DIRC counters.

PANDA experiment and International Standard Problem for passive cooling systems for afterheat removal

International Nuclear Information System (INIS)

Yadigaroglu, G.; Aksan, N.S.

1999-01-01

In the context of OECD/NEA, Paul Scherrer Institut (PSI) is working on an International Standard Problem which is to provide information on the efficiency and use of computer program systems for passive afterheat removal systems. The PANDA test facility of PSI was designed for these investigations. A six-phase PANDA experiment provides a basis for pre-calculation and recalculation of selected phases covering a limited number of system-typical operating states and phenomena. The experiment was specified and carried out in the year under report [de

Integration Of PanDA Workload Management System With Supercomputers for ATLAS and Data Intensive Science

Energy Technology Data Exchange (ETDEWEB)

De, K [University of Texas at Arlington; Jha, S [Rutgers University; Klimentov, A [Brookhaven National Laboratory (BNL); Maeno, T [Brookhaven National Laboratory (BNL); Nilsson, P [Brookhaven National Laboratory (BNL); Oleynik, D [University of Texas at Arlington; Panitkin, S [Brookhaven National Laboratory (BNL); Wells, Jack C [ORNL; Wenaus, T [Brookhaven National Laboratory (BNL)

2016-01-01

The Large Hadron Collider (LHC), operating at the international CERN Laboratory in Geneva, Switzerland, is leading Big Data driven scientific explorations. Experiments at the LHC explore the fundamental nature of matter and the basic forces that shape our universe, and were recently credited for the discovery of a Higgs boson. ATLAS, one of the largest collaborations ever assembled in the sciences, is at the forefront of research at the LHC. To address an unprecedented multi-petabyte data processing challenge, the ATLAS experiment is relying on a heterogeneous distributed computational infrastructure. The ATLAS experiment uses PanDA (Production and Data Analysis) Workload Management System for managing the workflow for all data processing on over 150 data centers. Through PanDA, ATLAS physicists see a single computing facility that enables rapid scientific breakthroughs for the experiment, even though the data centers are physically scattered all over the world. While PanDA currently uses more than 250,000 cores with a peak performance of 0.3 petaFLOPS, LHC data taking runs require more resources than Grid computing can possibly provide. To alleviate these challenges, LHC experiments are engaged in an ambitious program to expand the current computing model to include additional resources such as the opportunistic use of supercomputers. We will describe a project aimed at integration of PanDA WMS with supercomputers in United States, Europe and Russia (in particular with Titan supercomputer at Oak Ridge Leadership Computing Facility (OLCF), MIRA supercomputer at Argonne Leadership Computing Facilities (ALCF), Supercomputer at the National Research Center Kurchatov Institute , IT4 in Ostrava and others). Current approach utilizes modified PanDA pilot framework for job submission to the supercomputers batch queues and local data management, with light-weight MPI wrappers to run single threaded workloads in parallel on LCFs multi-core worker nodes. This implementation

Metagenomic Study Suggests That the Gut Microbiota of the Giant Panda (Ailuropoda melanoleuca) May Not Be Specialized for Fiber Fermentation

OpenAIRE

Wei Guo; Sudhanshu Mishra; Jiangchao Zhao; Jingsi Tang; Bo Zeng; Fanli Kong; Ruihong Ning; Miao Li; Hengzhi Zhang; Yutian Zeng; Yuanliangzi Tian; Yihang Zhong; Hongdi Luo; Yunhan Liu; Jiandong Yang

2018-01-01

Bamboo-eating giant panda (Ailuropoda melanoleuca) is an enigmatic species, which possesses a carnivore-like short and simple gastrointestinal tract (GIT). Despite the remarkable studies on giant panda, its diet adaptability status continues to be a matter of debate. To resolve this puzzle, we investigated the functional potential of the giant panda gut microbiome using shotgun metagenomic sequencing of fecal samples. We also compared our data with similar data from other animal species repre...

Calidad de Vida Profesional y Síndrome de Burnout del personal de salud del Servicio de Cuidado Crítico Neonatal del Hospital “San Bartolomé”, Lima – 2014

OpenAIRE

Rojas Salinas, Jakelina Marly; Pintado Dávila, Janet

2015-01-01

Conocer la calidad de vida profesional y el Síndrome de Burnout del personal de salud es muy importante porque ambos pueden determinar el rendimiento laboral, la obtención de mejores resultados y una elevada productividad. Objetivo: Describir las características de la Calidad de Vida Profesional y el Síndrome de Burnout del personal de salud del Servicio de Cuidado Crítico Neonatal del Hospital “San Bartolomé”, Lima -2014. Material y Método: Se ha realizado un estudio de enf...

The use of the gonadotropin-releasing hormone analog deslorelin for short-term contraception in red pandas (Ailurus fulgens).

Science.gov (United States)

Koeppel, Katja N; Barrows, Michelle; Visser, Katherine

2014-01-15

Red pandas (Ailurus fulgens) are threatened with extinction owing to habitat loss, exacerbated by their unique ecology and low fecundity. Regional breeding programs manage captive red panda populations. Recommendations not to breed may be made for various reasons, including genetic overrepresentation of certain individuals. No recommendations have been published on the use of contraception for red pandas. This article discusses the use of the GnRH analog deslorelin as a reversible method of contraception in both male and female pandas. The mean time from last contraception to conception was 3 years with a 4.6-mg deslorelin implant. The average dose of GnRH implant received was 1.09 mg/kg (range, 0.88-1.32). Males returned to breeding sooner than females. No reproductive side effects were noted with up to three consecutive annual GnRH implants. Copyright © 2014 Elsevier Inc. All rights reserved.

On the first occupational medicine initiatives in Mexico: The Real del Monte miners’ hospital.

Science.gov (United States)

Gómez, José Luis; Rodríguez-Paz, Carlos Agustín

2018-01-01

Despite the legislation of Otto von Bismarck (1815-1898) on social security rights formulated in 1883 in Germany where it is stated that it is the duty of the State to promote the welfare of all members of society, particularly the weakest and most needy, using the means available to them, and the proposals of laws against accidents issued on April 30, 1904 in the State of Mexico in 1904, in the Mexico of the Porfirio Díaz era, providing workers with formal medical care was not contemplated, except in the case of some railway companies, hospitals for the care of patients with occupational diseases were not built. One of these exceptions was the Hospital del Mineral del Real del Monte de Pachuca, founded in the late nineteenth century and after the mining company passed to the Americans in 1906, it was agreed that the company acquired the hospital and equated it with the medical and surgical advances of the time for immediate care of injuries, especially of the orthopedic type, which enabled not only the healing of wounds, but also rehabilitation. This hospital is one of the oldest in Mexico with regard to three disciplines: orthopedics, occupational medicine and rehabilitation. It ceased to operate in 1982, and currently it is a museum with a rich collection of documents and instruments related to the aforementioned disciplines. Copyright: © 2018 SecretarÍa de Salud.

PanDA for ATLAS distributed computing in the next decade

Science.gov (United States)

Barreiro Megino, F. H.; De, K.; Klimentov, A.; Maeno, T.; Nilsson, P.; Oleynik, D.; Padolski, S.; Panitkin, S.; Wenaus, T.; ATLAS Collaboration

2017-10-01

The Production and Distributed Analysis (PanDA) system has been developed to meet ATLAS production and analysis requirements for a data-driven workload management system capable of operating at the Large Hadron Collider (LHC) data processing scale. Heterogeneous resources used by the ATLAS experiment are distributed worldwide at hundreds of sites, thousands of physicists analyse the data remotely, the volume of processed data is beyond the exabyte scale, dozens of scientific applications are supported, while data processing requires more than a few billion hours of computing usage per year. PanDA performed very well over the last decade including the LHC Run 1 data taking period. However, it was decided to upgrade the whole system concurrently with the LHC’s first long shutdown in order to cope with rapidly changing computing infrastructure. After two years of reengineering efforts, PanDA has embedded capabilities for fully dynamic and flexible workload management. The static batch job paradigm was discarded in favor of a more automated and scalable model. Workloads are dynamically tailored for optimal usage of resources, with the brokerage taking network traffic and forecasts into account. Computing resources are partitioned based on dynamic knowledge of their status and characteristics. The pilot has been re-factored around a plugin structure for easier development and deployment. Bookkeeping is handled with both coarse and fine granularities for efficient utilization of pledged or opportunistic resources. An in-house security mechanism authenticates the pilot and data management services in off-grid environments such as volunteer computing and private local clusters. The PanDA monitor has been extensively optimized for performance and extended with analytics to provide aggregated summaries of the system as well as drill-down to operational details. There are as well many other challenges planned or recently implemented, and adoption by non-LHC experiments such

Parallel algorithms for online trackfinding at PANDA

Energy Technology Data Exchange (ETDEWEB)

Bianchi, Ludovico; Ritman, James; Stockmanns, Tobias [IKP, Forschungszentrum Juelich GmbH (Germany); Herten, Andreas [JSC, Forschungszentrum Juelich GmbH (Germany); Collaboration: PANDA-Collaboration

2016-07-01

The PANDA experiment, one of the four scientific pillars of the FAIR facility currently in construction in Darmstadt, is a next-generation particle detector that will study collisions of antiprotons with beam momenta of 1.5-15 GeV/c on a fixed proton target. Because of the broad physics scope and the similar signature of signal and background events, PANDA's strategy for data acquisition is to continuously record data from the whole detector and use this global information to perform online event reconstruction and filtering. A real-time rejection factor of up to 1000 must be achieved to match the incoming data rate for offline storage, making all components of the data processing system computationally very challenging. Online particle track identification and reconstruction is an essential step, since track information is used as input in all following phases. Online tracking algorithms must ensure a delicate balance between high tracking efficiency and quality, and minimal computational footprint. For this reason, a massively parallel solution exploiting multiple Graphic Processing Units (GPUs) is under investigation. The talk presents the core concepts of the algorithms being developed for primary trackfinding, along with details of their implementation on GPUs.

Test of a PCIe based readout option for PANDA

Energy Technology Data Exchange (ETDEWEB)

Reiter, Simon; Lange, Soeren; Kuehn, Wolfgang [Justus-Liebig-Universitaet Giessen (Germany); Engel, Heiko [Goethe-Universitaet Frankfurt (Germany); Collaboration: PANDA-Collaboration

2016-07-01

The future PANDA detector will achieve an event rate at about 20 MHz resulting in a high data load of up to 200 GB/s. The data acquisition system will be based on a triggerless readout concept, leading to the requirement of large data bandwidths. The data reduction will be guaranteed on the first level by an array of FPGAs running a full on-line reconstruction followed by the second level of a CPU/GPU cluster to achieve a reduction factor more than 1000. The C-RORC (Common Readout Receiver Card), originally developed for ALICE, provides on the one hand 12 optical links with 6.25 Gbps each, and on the other hand a PCIe interface with up to 40 Gbps. The receiver card has been installed and tested, and the firmware has been adjusted for the Panda data format. Test results are presented.

A time digitizer for the microstrip detectors of the PANDA MVD

Energy Technology Data Exchange (ETDEWEB)

Riccardi, Alberto; Brinkmann, Kai-Thomas; Di Pietro, Valentino [II. Physikalisches Institut, Justus-Liebig-Universitaet Giessen (Germany); Garbolino, Sara; Rivetti, Angelo; Rolo, Manuel [INFN Sezione di Torino, Torino (Italy); Collaboration: PANDA-Collaboration

2015-07-01

In nuclear detectors the information on the energy of the particle is usually obtained by measuring the amplitude of the signal delivered by the sensor. The low voltage power supply used in modern deep submicron technologies constrain the maximum dynamic range of the ADC. Still, the energy information can be obtained with time-based techniques, in which the energy is associated with the duration of the signal through the Time over Threshold method. This work is focused on the PANDA Micro Vertex Detector and explores the possibility of applying a time-based readout approach for the microstrip sensors. In PANDA, the strip system must cope with hit rates up to 50 kHz per channel. Therefore, the front-end output must be relatively short, this implies that the clock resolution is not enough to measure the signal duration, so it is necessary to use a Time to Digital Converter. The front-end and the TDC structure are designed in a 0.11μm CMOS process. The TDC chosen is based on an analog clock interpolator because it combines good time resolution with a fairly simple implementation and low power consumption. In the presentation an overview of the analog part of the PASTA (PANDA strip ASIC) is presented.

Determination of the Ds0(2317) width with the PANDA detector

International Nuclear Information System (INIS)

Mertens, Marius Christian

2012-01-01

The D s0 *(2317) meson which was discovered at BaBar in 2003 has the interesting properties of a surprisingly narrow width and a mass just below the DK threshold. Different theoretical models try to explain the nature of its properties. A precise knowledge of the width is an important criterion to evaluate these models. However, only an upper limit of 3.8 MeV is known so far. A suitable method to determine the width of particles which are significantly narrower than the experimental mass resolution is to measure the production cross section as a function of the center of mass energy. The shape of this excitation function allows to deduce the width. At PANDA, the measurement of the production cross section will be possible in antiproton-proton collisions. The PANDA experiment at the future FAIR facility is designed to combine precisely adjustable beam momenta and high luminosities which make it an excellent tool for this kind of measurement. In the following we will describe the experimental procedure to carry out this measurement with the PANDA detector in order to achieve a resolution in the order of 0.1 MeV for the width of the D s0 *(2317).

A Mathematical Model with Pulse Effect for Three Populations of the Giant Panda and Two Kinds of Bamboo

Directory of Open Access Journals (Sweden)

Xiang-yun Shi

2013-01-01

Full Text Available A mathematical model for the relationship between the populations of giant pandas and two kinds of bamboo is established. We use the impulsive perturbations to take into account the effect of a sudden collapse of bamboo as a food source. We show that this system is uniformly bounded. Using the Floquet theory and comparison techniques of impulsive equations, we find conditions for the local and global stabilities of the giant panda-free periodic solution. Moreover, we obtain sufficient conditions for the system to be permanent. The results provide a theoretical basis for giant panda habitat protection.

Crystal chemistry of pyrochlore from the Mesozoic Panda Hill carbonatite deposit, western Tanzania

Science.gov (United States)

Boniface, Nelson

2017-02-01

The Mesozoic Panda Hill carbonatite deposit in western Tanzania hosts pyrochlore, an ore and source of niobium. This study was conducted to establish the contents of radioactive elements (uranium and thorium) in pyrochlore along with the concentration of niobium in the ore. The pyrochlore is mainly hosted in sövite and is structurally controlled by NW-SE (SW dipping) or NE-SW (NW dipping) magmatic flow bands with dip angles of between 60° and 90°. Higher concentrations of pyrochlore are associated with magnetite, apatite and/or phlogopite rich flow bands. Electron microprobe analyses on single crystals of pyrochlore yield very low UO2 concentrations that range between 0 and 0.09 wt% (equivalent to 0 atoms per formula unit: a.p.f.u.) and ThO2 between 0.55 and 1.05 wt% (equivalent to 0.1 a.p.f.u.). The analyses reveal high concentrations of Nb2O5 (ranging between 57.13 and 65.50 wt%, equivalent to a.p.f.u. ranging between 1.33 and 1.43) and therefore the Panda Hill Nb-oxide is classified as pyrochlore sensu stricto. These data point to a non radioactive pyrochlore and a deposit rich in Nb at Panda Hill. The Panda Hill pyrochlore has low concentrations of REEs as displayed by La2O3 that range between 0.10 and 0.49 wt% (equivalent to a.p.f.u. ranging between 0 and 0.01) and Ce2O3 ranging between 0.86 and 1.80 wt% (equivalent to a.p.f.u. ranging between 0.02 and 0.03), Pr2O3 concentrations range between 0 and 0.23 wt% (equivalent to 0 a.p.f.u.), and Y2O3 is 0 wt% (equivalent to 0 a.p.f.u.). The abundance of the REEs in pyroclore at the Panda Hill Carbonatite deposit is of no economic significance.

Tests of optical glues for the PANDA electromagnetic calorimeter

NARCIS (Netherlands)

Dbeyssi, A.; Tomasi-Gustafsson, E.; Hennino, T.; Imre, M.; Kunne, R.; Le Galliard, C.; Marchand, D.; Maroni, A.; Ramstein, B.; Rosier, P.; Bremer, D.; Dormenev, V.; Eissner, T.; Kuske, T.; Novotny, R.; Moeini, H.; Bondarenko, O.; Kavatsyuk, M.; Loehner, H.; Messchendorp, G.; Tambave, G.

2013-01-01

This paper reports on the results of tests for low temperature applications of two commercial optical glues in the electromagnetic calorimeter of PANDA at FAIR. Mechanical, thermal and optical properties are presented, as well as radiation hardness to photon and proton radiation. (C) 2013 Elsevier

PANDA: a Large Scale Multi-Purpose Test Facility for LWR Safety Research

Energy Technology Data Exchange (ETDEWEB)

Dreier, Joerg; Paladino, Domenico; Huggenberger, Max; Andreani, Michele [Laboratory for Thermal-Hydraulics, Nuclear Energy and Safety Research Department, Paul Scherrer Institut (PSI), CH-5232 Villigen PSI (Switzerland); Yadigaroglu, George [ETH Zuerich, Technoparkstrasse 1, Einstein 22- CH-8005 Zuerich (Switzerland)

2008-07-01

PANDA is a large-scale multi-purpose thermal-hydraulics test facility, built and operated by PSI. Due to its modular structure, PANDA provides flexibility for a variety of applications, ranging from integral containment system investigations, primary system tests, component experiments to large-scale separate-effects tests. For many applications, the experimental results are directly used for example for concept demonstrations or for the characterisation of phenomena or components, but all the experimental data generated in the various test campaigns is unique and was or/and will still be widely used for the validation and improvement of a variety of computer codes, including codes with 3D capabilities, for reactor safety analysis. The paper provides an overview of the already completed and on-going research programs performed in the PANDA facility in the different area of applications, including the main results and conclusions of the investigations. In particular the advanced passive containment cooling system concept investigations of the SBWR, ESBWR as well as of the SWR1000 in relation to various aspects are presented and the main findings are summarised. Finally the goals, planned investigations and expected results of the on-going OECD project SETH-2 are presented. (authors)

PANDA: a Large Scale Multi-Purpose Test Facility for LWR Safety Research

International Nuclear Information System (INIS)

Dreier, Joerg; Paladino, Domenico; Huggenberger, Max; Andreani, Michele; Yadigaroglu, George

2008-01-01

PANDA is a large-scale multi-purpose thermal-hydraulics test facility, built and operated by PSI. Due to its modular structure, PANDA provides flexibility for a variety of applications, ranging from integral containment system investigations, primary system tests, component experiments to large-scale separate-effects tests. For many applications, the experimental results are directly used for example for concept demonstrations or for the characterisation of phenomena or components, but all the experimental data generated in the various test campaigns is unique and was or/and will still be widely used for the validation and improvement of a variety of computer codes, including codes with 3D capabilities, for reactor safety analysis. The paper provides an overview of the already completed and on-going research programs performed in the PANDA facility in the different area of applications, including the main results and conclusions of the investigations. In particular the advanced passive containment cooling system concept investigations of the SBWR, ESBWR as well as of the SWR1000 in relation to various aspects are presented and the main findings are summarised. Finally the goals, planned investigations and expected results of the on-going OECD project SETH-2 are presented. (authors)

Vaccine-induced canine distemper in a lesser panda.

Science.gov (United States)

Bush, M; Montali, R J; Brownstein, D; James, A E; Appel, M J

1976-11-01

A fatal disease occurred in a lesser panda (Ailurus fulgens) 2 weeks after vaccination with modified live distemper vaccine. The disease clinically resembled canine distemper. Pathologically there was giant cell pneumonia, with canine distemper viral inclusion bodies in pulmonary and digestive tract epithelium. Viral isolates were indicative of an attenuated strain rather than virulent types.

Conocimiento de la atención del paro cardiorrespiratorio en médicos del Hospital Pedro de Bethancourt

Directory of Open Access Journals (Sweden)

Henry Samayoa

2017-03-01

Full Text Available El paro cardiorrespiratorio (PCR es el cese de la respiración y el latido cardiaco en una persona. Las maniobras de reanimación cardiopulmonar (RCP son el conjunto de maniobras que se realizan con la finalidad de sustituir y restaurar la circulación y respiración espontánea en un paciente en PCR. El objetivo fue evaluar el conocimiento de la atención del PCR según Guías AHA 2010 en los médicos que laboran durante el año 2014 en el Hospital Pedro de Bethancourt de la Antigua Guatemala. Se realizó un estudio descriptivo comparativo. Para evaluar el conocimiento de la atención del PCR entre los médicos jefes (especialistas y médicos residentes, se utilizó un cuestionario de 30 preguntas sobre conocimientos de soporte vital básico y avanzado. Se logró la participación de 104 médicos. El promedio de calificación fue de 33 puntos para los Médicos Jefes y de 23 puntos para los Médicos Residentes. Los médicos que laboran en el Hospital Pedro de Bethancourt no tienen el conocimiento óptimo de la atención del PCR avanzado según las Guías de la AHA 2010.

Analysis of the cytochrome c oxidase subunit II (COX2) gene in giant panda, Ailuropoda melanoleuca.

Science.gov (United States)

Ling, S S; Zhu, Y; Lan, D; Li, D S; Pang, H Z; Wang, Y; Li, D Y; Wei, R P; Zhang, H M; Wang, C D; Hu, Y D

2017-01-23

The giant panda, Ailuropoda melanoleuca (Ursidae), has a unique bamboo-based diet; however, this low-energy intake has been sufficient to maintain the metabolic processes of this species since the fourth ice age. As mitochondria are the main sites for energy metabolism in animals, the protein-coding genes involved in mitochondrial respiratory chains, particularly cytochrome c oxidase subunit II (COX2), which is the rate-limiting enzyme in electron transfer, could play an important role in giant panda metabolism. Therefore, the present study aimed to isolate, sequence, and analyze the COX2 DNA from individuals kept at the Giant Panda Protection and Research Center, China, and compare these sequences with those of the other Ursidae family members. Multiple sequence alignment showed that the COX2 gene had three point mutations that defined three haplotypes, with 60% of the sequences corresponding to haplotype I. The neutrality tests revealed that the COX2 gene was conserved throughout evolution, and the maximum likelihood phylogenetic analysis, using homologous sequences from other Ursidae species, showed clustering of the COX2 sequences of giant pandas, suggesting that this gene evolved differently in them.

Microglial Dysregulation in OCD, Tourette Syndrome, and PANDAS

Directory of Open Access Journals (Sweden)

Luciana Frick

2016-01-01

Full Text Available There is accumulating evidence that immune dysregulation contributes to the pathophysiology of obsessive-compulsive disorder (OCD, Tourette syndrome, and Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS. The mechanistic details of this pathophysiology, however, remain unclear. Here we focus on one particular component of the immune system: microglia, the brain’s resident immune cells. The role of microglia in neurodegenerative diseases has been understood in terms of classic, inflammatory activation, which may be both a consequence and a cause of neuronal damage. In OCD and Tourette syndrome, which are not characterized by frank neural degeneration, the potential role of microglial dysregulation is much less clear. Here we review the evidence for a neuroinflammatory etiology and microglial dysregulation in OCD, Tourette syndrome, and PANDAS. We also explore new hypotheses as to the potential contributions of microglial abnormalities to pathophysiology, beyond neuroinflammation, including failures in neuroprotection, lack of support for neuronal survival, and abnormalities in synaptic pruning. Recent advances in neuroimaging and animal model work are creating new opportunities to elucidate these issues.

Microglial Dysregulation in OCD, Tourette Syndrome, and PANDAS

Science.gov (United States)

2016-01-01

There is accumulating evidence that immune dysregulation contributes to the pathophysiology of obsessive-compulsive disorder (OCD), Tourette syndrome, and Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS). The mechanistic details of this pathophysiology, however, remain unclear. Here we focus on one particular component of the immune system: microglia, the brain's resident immune cells. The role of microglia in neurodegenerative diseases has been understood in terms of classic, inflammatory activation, which may be both a consequence and a cause of neuronal damage. In OCD and Tourette syndrome, which are not characterized by frank neural degeneration, the potential role of microglial dysregulation is much less clear. Here we review the evidence for a neuroinflammatory etiology and microglial dysregulation in OCD, Tourette syndrome, and PANDAS. We also explore new hypotheses as to the potential contributions of microglial abnormalities to pathophysiology, beyond neuroinflammation, including failures in neuroprotection, lack of support for neuronal survival, and abnormalities in synaptic pruning. Recent advances in neuroimaging and animal model work are creating new opportunities to elucidate these issues. PMID:28053994

ATLAS World-cloud and networking in PanDA

CERN Document Server

Barreiro Megino, Fernando Harald; The ATLAS collaboration; De, Kaushik; Di Girolamo, Alessandro; Walker, Rodney

2016-01-01

The ATLAS computing model was originally designed as static clouds (usually national or geographical groupings of sites) around the Tier 1 centers, which confined tasks and most of the data traffic. Since those early days, the sites' network bandwidth has increased at O(1000) and the difference in functionalities between Tier 1s and Tier 2s has reduced. After years of manual, intermediate solutions, we have now ramped up to full usage of World-cloud, the latest step in the PanDA Workload Management System to increase resource utilization on the ATLAS Grid, for all workflows (MC production, data (re)processing, etc.). We have based the development on two new site concepts. Nuclei sites are the Tier 1s and large Tier 2s, where tasks will be assigned and the output aggregated, and satellites are the sites that will execute the jobs and send the output to their nucleus. Nuclei and satellite sites are dynamically paired by PanDA for each task based on the input data availability, capability matching, site load and...

ATLAS WORLD-cloud and networking in PanDA

CERN Document Server

AUTHOR|(SzGeCERN)643806; The ATLAS collaboration; De, Kaushik; Di Girolamo, Alessandro; Maeno, Tadashi; Walker, Rodney

2017-01-01

The ATLAS computing model was originally designed as static clouds (usually national or geographical groupings of sites) around the Tier 1 centres, which confined tasks and most of the data traffic. Since those early days, the sites' network bandwidth has increased at 0(1000) and the difference in functionalities between Tier 1s and Tier 2s has reduced. After years of manual, intermediate solutions, we have now ramped up to full usage of World-cloud, the latest step in the PanDA Workload Management System to increase resource utilization on the ATLAS Grid, for all workflows (MC production, data (re)processing, etc.). We have based the development on two new site concepts. Nuclei sites are the Tier 1s and large Tier 2s, where tasks will be assigned and the output aggregated, and satellites are the sites that will execute the jobs and send the output to their nucleus. PanDA dynamically pairs nuclei and satellite sites for each task based on the input data availability, capability matching, site load and network...

Influence of the distribution of non-condensables on passive containment condenser performance in PANDA

International Nuclear Information System (INIS)

Bandurski, Th.; Huggenberger, M.; Dreier, J.; Aubert, C.; Putz, F.; Gamble, R.E.; Yadigaroglu, G.

2001-01-01

Recently passive cooling systems have been designed for the long-term decay heat removal from the containment of Advanced Light Water Reactors. In particular, the long-term LOCA response of the Passive Containment Cooling System (PCCS) for the General Electric European Simplified Boiling Water Reactor (ESBWR) has been tested in the large-scale PANDA facility. The PANDA tests achieved the dual objectives of improving confidence in the performance of the passive heat removal mechanisms underlying the design of the system, and extending the database available for containment analysis code qualification. The tests conducted subject the PCCS to a variety of conditions representing design-basis and beyond-design-basis accident conditions. These include operation in the presence of both heavier and lighter than steam non-condensable gases, as well as a variety of asymmetric and challenging start-up conditions. The present paper addresses the transient distribution of non-condensables in PANDA, and their effect on (passive) condenser performance. (author)

Influence of the distribution of non-condensables on passive containment condenser performance in PANDA

Energy Technology Data Exchange (ETDEWEB)

Bandurski, Th.; Huggenberger, M.; Dreier, J.; Aubert, C.; Putz, F.; Gamble, R.E.; Yadigaroglu, G

2001-03-01

Recently passive cooling systems have been designed for the long-term decay heat removal from the containment of Advanced Light Water Reactors. In particular, the long-term LOCA response of the Passive Containment Cooling System (PCCS) for the General Electric European Simplified Boiling Water Reactor (ESBWR) has been tested in the large-scale PANDA facility. The PANDA tests achieved the dual objectives of improving confidence in the performance of the passive heat removal mechanisms underlying the design of the system, and extending the database available for containment analysis code qualification. The tests conducted subject the PCCS to a variety of conditions representing design-basis and beyond-design-basis accident conditions. These include operation in the presence of both heavier and lighter than steam non-condensable gases, as well as a variety of asymmetric and challenging start-up conditions. The present paper addresses the transient distribution of non-condensables in PANDA, and their effect on (passive) condenser performance. (author)

Online cluster-finding algorithms for the PANDA electromagnetic calorimeter

NARCIS (Netherlands)

Tiemens, Marcel

2017-01-01

Om zeldzame processen zoals de vorming van exotische deeltjes te kunnen bestuderen, is het PANDA experiment opgezet. Om de grote hoeveelheden data te kunnen verwerken, verwerken de subsystemen de data voor. Een voorbeeld is het algoritme om online naar clusters te zoeken in de data van de

Dietary shift and dysbiosis may trigger mucous stools in giant pandas (Ailuropoda melanoleuca

Directory of Open Access Journals (Sweden)

Candace L Williams

2016-05-01

Full Text Available Dietary shifts can result in dysbiosis between the host and its gastrointestinal tract (GIT microbiota, leading to negative outcomes including inflammation. Giant pandas (Ailuropoda melanoleuca are physiologically classified as carnivores; however, they consume a herbivorous diet with dramatic seasonal feeding shifts and episodes of chronic GIT distress with symptoms including abdominal pain, loss of appetite and the excretion of mucous stools (mucoids. These episodes adversely affect the overall nutritional and health status of giant pandas. Here, we examined the fecal microbiota of two giant pandas’ normal and mucoid stools and compared these microbiota to baseline samples from a season with historically few episodes. To identify the microbiota present, we isolated and sequenced 16S rRNA using next-generation sequencing. Mucoids occurred following a seasonal feeding switch from predominately bamboo culm (stalk to leaves. All fecal samples displayed low diversity and were dominated by bacterial in the phyla Firmicutes and to a lesser extent, the Proteobacteria. Fecal samples immediately prior to mucoid episodes had lower microbial diversity compared to baseline samples, followed by increased diversity in mucoids. Mucoids were mostly comprised of common mucosal-associated taxa including Streptococcus and Leuconostoc species, and exhibited increased abundance for bacteria in the family Pasteurellaceae. Taken together, these findings indicate that diet-induced intestinal dysbiosis in giant pandas likely results in an expulsion of the mucosal lining in the form of mucoids. We suggest that these occurrences serve to reset their GIT microbiota, as giant pandas have retained a carnivorous GIT anatomy while shifting to an herbivorous diet.

A test system for electronics components of the PANDA MVD

Energy Technology Data Exchange (ETDEWEB)

Lai, Alessandra; Stockmanns, Tobias; Ritman, James [Forschungszentrum Juelich (Germany); Collaboration: PANDA-Collaboration

2016-07-01

The PANDA experiment is one of the main devices at the upcoming Facility for Antiproton and Ion Research(FAIR), under construction in Darmstadt, Germany. This fixed target experiment will study the transition region between perturbative and non-perturbative QCD in the energy regime of the charmonium. The innermost sub-detector system of the target spectrometer of the PANDA experiment is the Micro Vertex Detector(MVD). Two types of silicon detectors will be used: pixel detectors and double-sided strip detectors. Two front-end chips are required: the Torino Pixel ASIC(ToPix) and the PANDA Strip ASIC(PASTA). Both are designed to transmit data at a rate of several hundred Megabits per second and are capable of handling the expected hit rate in hot spots of the detector. One key component in the development of new front-end electronics is a test system capable to handle these high rates. It should be flexible enough to test different kinds of front-end electronics and it should be easy to adapt to new prototypes. Therefore, an FPGA-based system is the ideal candidate. For this test system suitable firmware and a software framework are needed. Such a system is under development at the Forschungszentrum Juelich. The main component of the Juelich Digital Readout System(JDRS) is a Virtex 6 FPGA on a development board from Xilinx. In this talk, the mentioned read-out system are introduced, and lab tests with the front-end electronics of the MVD are presented.

La experiencia del Hospital Clínic de Barcelona: integración Facultad de Medicina - IDIBAPS - Hospital Universitario

Directory of Open Access Journals (Sweden)

Juan Rodés

Full Text Available La investigación traslacional es una nueva disciplina que incorpora aspectos de ciencia básica e investigación clínica y, por tanto, requiere entrenamiento y recursos que no se suelen encontrar en los laboratorios o en departamentos clínicos. Es por ello que los institutos donde se combinan ambos tipos de investigación como universidades, centros de investigación básica y hospitales de alto nivel asistencial, son las instituciones ideales para realizar este tipo de investigación. En el Hospital Clínic de Barcelona se ha producido un cambio en el transcurso de los últimos 40 años. Este cambio ha venido marcado por varios hechos, a destacar la creación de los servicios clínicos que substituyeron a las antiguas cátedras, la creación de los servicios de medicina, las becas post-residencia, los años sabáticos, la Fundación Clínic para la Investigación Biomédica y finalmente la puesta en marcha del Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS. En los últimos años es importante destacar también la reorganización del hospital en institutos y centros. La producción científica en estos últimos años se ha mantenido en alza, tanto en número de publicaciones como del impacto de las revistas en las que se publica. El IDIBAPS ha alcanzado unos resultados similares a los obtenidos por los mejores institutos de investigación del mundo occidental.

Revitalización parcial del Hospital de las Cinco Llagas de Sevilla como sede del Parlamento de Andalucía

Directory of Open Access Journals (Sweden)

Rodríguez Pérez, Pedro

1994-02-01

Full Text Available The Hospital of the Cinco Llagas of Sevilla was designed by Martín Gaínza in the middle of XVI century. It had patient's rooms disposed in the form of a double cross surrounded by patios with exterior perimetric aisles making up a large rectangular floor. The church, created by Hernán Ruiz el Mozo, is located in the principal patio and, with its height and its grim volume, it dominates the horizontal mass of the whole, representing a magnificent background for the esplanade which separates it from the Almohad city walls. Tills remarkable building which had preserved its medical function until a little longer than a decade ago, has been the seat of the Parliament of Andalucía since 28 February, 1992. This article is a brief summary of the history of the Hospital, its condition at the beginning of the eighties and of the studies, projects and the works carried out on the building in order to restore it and adapt it to the new use.

El Hospital de las Cinco Llagas de Sevilla fue trazado por Martín de Gaínza a mediados del siglo XVI, disponiendo las salas de enfermos en doble crucero y rodeándolas por patios cuyas naves perimetrales exteriores completan una gran planta rectangular. La iglesia, creada por Hernán Ruíz el Mozo, se sitúa en el patio principal, dominando con su gran altura y su severo volumen la masa horizontal del conjunto, soberbio telón de fondo de la explanada que lo separa de la muralla almohade de la ciudad. El notable edificio, que ha conservado su función sanitaria hasta hace poco más de una década, es desde el veintiocho de febrero de 1992 la sede del Parlamento de Andalucía. Este artículo es un apretado resumen de la historia del viejo Hospital, de su estado a principio de los años ochenta y de los estudios, proyectos y obras llevadas a cabo sobre él para restaurarlo y adaptarlo a los nuevos usos.

Material screening with HPGe counting station for PandaX experiment

International Nuclear Information System (INIS)

Wang, X.; Chen, X.; Fu, C.; Ji, X.; Liu, X.; Xie, P.; Zhang, T.; Mao, Y.; Wang, S.; Wang, H.

2016-01-01

A gamma counting station based on high-purity germanium (HPGe) detector was set up for the material screening of the PandaX dark matter experiments in the China Jinping Underground Laboratory. Low background gamma rate of 2.6 counts/min within the energy range of 20 to 2700 keV is achieved due to the well-designed passive shield. The sentivities of the HPGe detetector reach mBq/kg level for isotopes like K, U, Th, and even better for Co and Cs, resulted from the low-background rate and the high relative detection efficiency of 175%. The structure and performance of the counting station are described in this article. Detailed counting results for the radioactivity in materials used by the PandaX dark-matter experiment are presented. The upgrading plan of the counting station is also discussed.

Role of New Nature Reserve in Assisting Endangered Species Conservation - Case Study of Giant Pandas in the Northern Qionglai Mountains, China.

Directory of Open Access Journals (Sweden)

Tian-Pei Guan

Full Text Available The creation of nature reserves is the most direct way to save endangered species populations and their habitat. Development of the giant panda (Ailuropoda melanoleuca nature reserve network in China was initiated in the 1960s, though the effort to create new reserves boomed considerably after the year 2000. Given this rapid development of protected areas in panda habitats, and the potential conflicting interests between conservation administrations and local economic development, it is essential to assess the role of new nature reserves in the overall giant panda conservation effort and reserve network. We utilized data from national giant panda surveys conducted in 2000 and 2012 to compare the size, spatial use, and distribution of panda populations, as well as the habitat suitability and connectivity in the Northern Qionglai Mountains between the two survey years. Our results show that although the total giant panda population in the study area did not change remarkably, local changes did occur. Most notably, the population in Wolong Nature Reserve declined by 27.3% (N = 39 and the population in Caopo Nature Reserve increased by 71.4% (N = 29 over the 12-year study period. We also found habitat suitability and availability decreased in both Wolong (12.4% and Caopo (7.4%, but that the relative density of giant pandas declined (19.2% and increased (84.6% at each site, respectively. The distance between centers of high IUA were more distant in 2012 (14.1±1.9km than that in 2000 (6.1±0.9km; t = -7.4, df = 5, p = 0.001, showing a scattered spatial pattern. Habitat availability decreased by 42% within the corridor between the two reserves, however panda occurrences in the corridor increased 24.6%. Compared to the total number of encounters, the proportion of the corridor increased 45.76%. Our results show the importance and success of the newly established Caopo to the conservation of giant pandas, and how crucial it is to identify and repair

PANDA Grid – a Tool for Physics

International Nuclear Information System (INIS)

Protopopescu, D; Schwarz, K

2011-01-01

PANDA Grid is the computing tool of the P-bar ANDA experiment at FAIR with concerted efforts dedicated to evolving it beyond passive computing infrastructure, into a complete and transparent solution for physics simulation, reconstruction and analysis, a tool right at the fingertips of the physicist. P-bar ANDA's position within the larger FAIR community, synergies with other FAIR experiments and with ALICE-LHC, together with recent progress are reported.

Genome-wide survey and analysis of microsatellites in giant panda (Ailuropoda melanoleuca), with a focus on the applications of a novel microsatellite marker system.

Science.gov (United States)

Huang, Jie; Li, Yu-Zhi; Du, Lian-Ming; Yang, Bo; Shen, Fu-Jun; Zhang, He-Min; Zhang, Zhi-He; Zhang, Xiu-Yue; Yue, Bi-Song

2015-02-07

The giant panda (Ailuropoda melanoleuca) is a critically endangered species endemic to China. Microsatellites have been preferred as the most popular molecular markers and proven effective in estimating population size, paternity test, genetic diversity for the critically endangered species. The availability of the giant panda complete genome sequences provided the opportunity to carry out genome-wide scans for all types of microsatellites markers, which now opens the way for the analysis and development of microsatellites in giant panda. By screening the whole genome sequence of giant panda in silico mining, we identified microsatellites in the genome of giant panda and analyzed their frequency and distribution in different genomic regions. Based on our search criteria, a repertoire of 855,058 SSRs was detected, with mono-nucleotides being the most abundant. SSRs were found in all genomic regions and were more abundant in non-coding regions than coding regions. A total of 160 primer pairs were designed to screen for polymorphic microsatellites using the selected tetranucleotide microsatellite sequences. The 51 novel polymorphic tetranucleotide microsatellite loci were discovered based on genotyping blood DNA from 22 captive giant pandas in this study. Finally, a total of 15 markers, which showed good polymorphism, stability, and repetition in faecal samples, were used to establish the novel microsatellite marker system for giant panda. Meanwhile, a genotyping database for Chengdu captive giant pandas (n = 57) were set up using this standardized system. What's more, a universal individual identification method was established and the genetic diversity were analysed in this study as the applications of this marker system. The microsatellite abundance and diversity were characterized in giant panda genomes. A total of 154,677 tetranucleotide microsatellites were identified and 15 of them were discovered as the polymorphic and stable loci. The individual

Violencia laboral externa en el ámbito de urgencias generales del Hospital Universitario Virgen del Rocío de Sevilla

Directory of Open Access Journals (Sweden)

Tatiana Chagoyen Barroso

Full Text Available Introducción: En los últimos años se ha incrementado la violencia laboral, y un sector de los más afectados es el sanitario. En la actualidad, está cobrando importancia la violencia laboral en el personal de urgencias. Las agresiones suelen ser por parte de los usuarios y, en ocasiones de sus familiares, a los profesionales de la Salud. Objetivos: Conocer si los trabajadores de Urgencias Generales del Hospital Universitario Virgen del Rocío (HUVR saben de la existencia de un plan de prevención y atención de agresiones para los profesionales del sistema público de Andalucía. Conocer agresiones no registradas hacia el personal de urgencias en HUVR. Material y métodos: Se trata de un estudio observacional, descriptivo con 221 trabajadores (68 varones y 153 mujeres, a los que se les entrega un cuestionario sobre la Violencia Laboral Externa (VLE percibida durante los 2 últimos años; se realiza un estudio descriptivo con análisis de frecuencias. Y posteriormente, se realizará test de Chi Cuadrado o prueba exacta de Fisher para ver si existe relación entre variables categóricas. Resultados: De 221 trabajadores que realizaron la encuesta, solo 26 conocen el plan de agresiones de HUVR. De 127 agresiones en los 2 últimos años, solo se registraron 13 (no existe significación estadística con sexo, edad o categoría profesional. Conclusiones: Existe infradeclaración de agresiones y un claro desconocimiento del plan de agresiones en el Hospital Universitario Virgen del Rocío.

A systematic study of the strong interaction with PANDA

NARCIS (Netherlands)

Messchendorp, J. G.; Hosaka, A; Khemchandani, K; Nagahiro, H; Nawa, K

2011-01-01

The theory of Quantum Chromo Dynamics (QCD) reproduces the strong interaction at distances much shorter than the size of the nucleon. At larger distance scales, the generation of hadron masses and confinement cannot yet be derived from first principles on basis of QCD. The PANDA experiment at FAIR

The PASTA chip. A free-running readout ASIC for silicon strip sensors in PANDA

Energy Technology Data Exchange (ETDEWEB)

Goerres, Andre; Stockmanns, Tobias; Ritman, James [Forschungszentrum Juelich GmbH, Juelich (Germany); Rivetti, Angelo [INFN Sezione di Torino, Torino (Italy); Collaboration: PANDA-Collaboration

2015-07-01

The PANDA experiment is a multi purpose detector, investigating hadron physics in the charm quark mass regime. It is one of the main experiments at the future FAIR accelerator facility, using anti pp annihilations from a 1.5-15 GeV/c anti-proton beam. Because of the broad physics spectrum and the similarity of event and background signals, PANDA does an event selection based on the complete raw data of the detector. The innermost of PANDA's sub-systems is the Micro Vertex Detector (MVD), consisting of silicon pixel and strip sensors. The latter will be read out by a specialized, free-running readout front-end called PANDA Strip ASIC (PASTA). It has to face a high event rate of up to 40 kHz/ch in an radiation-intense environment. To fulfill the MVD's requirements, it has to give accurate timing information to incoming events (<10 ns) and determine the collected charge with an 8-bit precision. All this has to be done with a very low power design (<4 mW/ch) on a small footprint with less than 21 mm{sup 2} and 60 μm input pitch for 64 channels per chip. Therefore, a simple, time-based readout approach with two independent thresholds is chosen. In this talk, the conceptual design of the full front-end and some aspects of the digital part are presented.

Exosomal microRNAs in giant panda (Ailuropoda melanoleuca) breast milk: potential maternal regulators for the development of newborn cubs.

Science.gov (United States)

Ma, Jideng; Wang, Chengdong; Long, Keren; Zhang, Hemin; Zhang, Jinwei; Jin, Long; Tang, Qianzi; Jiang, Anan; Wang, Xun; Tian, Shilin; Chen, Li; He, Dafang; Li, Desheng; Huang, Shan; Jiang, Zhi; Li, Mingzhou

2017-06-14

The physiological role of miRNAs is widely understood to include fine-tuning the post-transcriptional regulation of a wide array of biological processes. Extensive studies have indicated that exosomal miRNAs in the bodily fluids of various organisms can be transferred between living cells for the delivery of gene silencing signals. Here, we illustrated the expression characteristics of exosomal miRNAs in giant panda breast milk during distinct lactation periods and highlighted the enrichment of immune- and development-related endogenous miRNAs in colostral and mature giant panda milk. These miRNAs are stable, even under certain harsh conditions, via the protection of extracellular vesicles. These findings indicate that breast milk may facilitate the dietary intake of maternal miRNAs by infants for the regulation of postnatal development. We also detected exogenous plant miRNAs from the primary food source of the giant panda (bamboo) in the exosomes of giant panda breast milk that were associated with regulatory roles in basic metabolism and neuron development. This result suggested that dietary plant miRNAs are absorbed by host cells and subsequently secreted into bodily fluids as potential cross-kingdom regulators. In conclusion, exosomal miRNAs in giant panda breast milk may be crucial maternal regulators for the development of intrinsic 'slink' newborn cubs.

Proton electromagnetic form factors: present status and future perspectives at PANDA

Directory of Open Access Journals (Sweden)

Tomasi-Gustafsson E.

2015-01-01

Full Text Available Data and models on electromagnetic proton form factors are reviewed, highlighting the contribution foreseen by the PANDA collaboration. Electromagnetic hadron form factors contain essential information on the internal structure of hadrons. Precise and surprising data have been obtained at electron accelerators, applying the polarization method in electron-proton elastic scattering. At electron-positron colliders, using initial state radiation, BABAR measured proton time-like form factors in a wide time-like kinematical region and the BESIII collaboration will measure very precisely proton and neutron form factors in the threshold region. In the next future an antiproton beam with momentum up to 15 GeV/c will be available at FAIR (Darmstadt. Measurements of the reaction p̅ + p → e+ + e− by the PANDA collaboration will contribute to the individual determination of electric and magnetic form factors in the time-like region of momentum transfer squared, as well as to their first determination in the unphysical region (below the kinematical threshold, through the reaction p̅ + p → e+ + e− + π0. From the discussion on feasibility studies at PANDA, we focus on the consequences of such measurements in view of an unified description of form factors in the full kinematical region. We present models which have the necessary analytical requirements and apply to the data in the whole kinematical region.

Counterpart experimental study of ISP-42 PANDA tests on PUMA facility

International Nuclear Information System (INIS)

Yang, Jun; Choi, Sung-Won; Lim, Jaehyok; Lee, Doo-Yong; Rassame, Somboon; Hibiki, Takashi; Ishii, Mamoru

2013-01-01

Highlights: ► Counterpart tests were performed on two large-scale BWR integral facilities. ► Similarity of post-LOCA system behaviors observed between two tests. ► Passive core and containment cooling systems work as design in both tests. -- Abstract: A counterpart test to the Passive Nachwärmeabfuhr und Druckabbau Test Anlage (Passive Decay Heat Removal and Depressurization Test Facility, PANDA) International Standard Problem (ISP)-42 test was conducted at the Purdue University Multi-Dimensional Integral Test Assembly (PUMA) facility. Aimed to support code validation on a range of light water reactor (LWR) containment issues, the ISP-42 test consists of six sequential phases (Phases A–F) with separately defined initial and boundary conditions, addressing different stages of anticipated accident scenario and system responses. The counterpart test was performed from Phases A to D, which are within the scope of the normal integral tests performed on the PUMA facility. A scaling methodology was developed by using the PANDA facility as prototype and PUMA facility as test model, and an engineering scaling has been applied to the PUMA facility. The counterpart test results indicated that functions of passive safety systems, such as passive containment cooling system (PCCS) start-up, gravity-driven cooling system (GDCS) discharge, PCCS normal operation and overload function were confirmed in both the PANDA and PUMA facilities with qualitative similarities

Genetic consequences of historical anthropogenic and ecological events on giant pandas.

Science.gov (United States)

Zhu, Lifeng; Hu, Yibo; Qi, Dunwu; Wu, Hua; Zhan, Xiangjiang; Zhang, Zhejun; Bruford, Michael W; Wang, Jinliang; Yang, Xuyu; Gu, Xiaodong; Zhang, Lei; Zhang, Baowei; Zhang, Shanning; Wei, Fuwen

2013-10-01

The giant panda (Ailuropoda melanoleuca) was taken to the brink of extinction in the 1980s through a combination of deforestation, large-scale loss of bamboo in the core of its range, poaching, and zoo collection, causing over 1000 deaths from the 1950s. It was thought that the drastic population decline was likely to impose a severe impact on population viability. Here, based on temporal genotyping of individuals, we show that this rapid decline did not significantly reduce the overall effective population size and genetic variation of this species, or of the two focal populations (Minshan and Qionglai) that declined the most. These results are contrary to previously assumptions, probably because the population decline has not produced the expected negative impact due to the short time scale involved (at most 10 generations), or because previous surveys underestimated the population size at the time of decline. However, if present-day habitat fragmentation and limited migration of giant pandas remains, we predict a loss of genetic diversity across the giant pandas' range in the near future. Thus, our findings highlight the substantial resilience of this species when facing demographic and environmental stochasticity, but key conservation strategies, such as enhancing habitat connectivity and habitat restoration should be immediately implemented to retain the extant genetic variation and maintain long-term evolutionary potential of this endangered species.

Specialized consultant in radiological safety to the Ciudad del Carmen general hospital, PEMEX

International Nuclear Information System (INIS)

Angeles C, A.; Hernandez C, J. E.; Rodriguez A, F.; Garcia A, J.

2003-02-01

The Ciudad del Carmen general hospital, dependent of PEMEX, It request consultant of the ININ to be able to maintain their sanitary license for the use of X-ray equipment for the radiologic diagnostic.The proposal of the ININ was to be a program of technical attendance, schedule monthly to be able to solve the observations that are presented in the use of those equipment, and that the hospital can conserve its respective sanitary license.(Author)

Factores que interviene en la aplicación de medidas de bioseguridad del profesional de enfermería del Servicio de Centro Quirúrgico del Hospital Nacional Dos de Mayo

OpenAIRE

Camacuari Cárdenas, Feliman Salome

2017-01-01

Determina los factores que intervienen en la aplicación de medidas de bioseguridad del profesional de enfermería del Servicio de Centro Quirúrgico (SCQ) del Hospital Nacional Dos de Mayo (HNDM). Estudio de tipo cuantitativo, método descriptivo de corte transversal. La población en estudio está constituida por 30 profesionales de enfermería que laboran en el SCQ. La técnica utilizada es la encuesta y el instrumento un cuestionario estructurado. Se llega a la conclusión que los factores desfavo...

Ancient DNA from Giant Panda (Ailuropoda melanoleuca) of South-Western China Reveals Genetic Diversity Loss during the Holocene.

Science.gov (United States)

Sheng, Gui-Lian; Barlow, Axel; Cooper, Alan; Hou, Xin-Dong; Ji, Xue-Ping; Jablonski, Nina G; Zhong, Bo-Jian; Liu, Hong; Flynn, Lawrence J; Yuan, Jun-Xia; Wang, Li-Rui; Basler, Nikolas; Westbury, Michael V; Hofreiter, Michael; Lai, Xu-Long

2018-04-06

The giant panda was widely distributed in China and south-eastern Asia during the middle to late Pleistocene, prior to its habitat becoming rapidly reduced in the Holocene. While conservation reserves have been established and population numbers of the giant panda have recently increased, the interpretation of its genetic diversity remains controversial. Previous analyses, surprisingly, have indicated relatively high levels of genetic diversity raising issues concerning the efficiency and usefulness of reintroducing individuals from captive populations. However, due to a lack of DNA data from fossil specimens, it is unknown whether genetic diversity was even higher prior to the most recent population decline. We amplified complete cyt b and 12s rRNA, partial 16s rRNA and ND1 , and control region sequences from the mitochondrial genomes of two Holocene panda specimens. We estimated genetic diversity and population demography by analyzing the ancient mitochondrial DNA sequences alongside those from modern giant pandas, as well as from other members of the bear family (Ursidae). Phylogenetic analyses show that one of the ancient haplotypes is sister to all sampled modern pandas and the second ancient individual is nested among the modern haplotypes, suggesting that genetic diversity may indeed have been higher earlier during the Holocene. Bayesian skyline plot analysis supports this view and indicates a slight decline in female effective population size starting around 6000 years B.P., followed by a recovery around 2000 years ago. Therefore, while the genetic diversity of the giant panda has been affected by recent habitat contraction, it still harbors substantial genetic diversity. Moreover, while its still low population numbers require continued conservation efforts, there seem to be no immediate threats from the perspective of genetic evolutionary potential.

Ancient DNA from Giant Panda (Ailuropoda melanoleuca of South-Western China Reveals Genetic Diversity Loss during the Holocene

Directory of Open Access Journals (Sweden)

Gui-Lian Sheng

2018-04-01

Full Text Available The giant panda was widely distributed in China and south-eastern Asia during the middle to late Pleistocene, prior to its habitat becoming rapidly reduced in the Holocene. While conservation reserves have been established and population numbers of the giant panda have recently increased, the interpretation of its genetic diversity remains controversial. Previous analyses, surprisingly, have indicated relatively high levels of genetic diversity raising issues concerning the efficiency and usefulness of reintroducing individuals from captive populations. However, due to a lack of DNA data from fossil specimens, it is unknown whether genetic diversity was even higher prior to the most recent population decline. We amplified complete cytb and 12s rRNA, partial 16s rRNA and ND1, and control region sequences from the mitochondrial genomes of two Holocene panda specimens. We estimated genetic diversity and population demography by analyzing the ancient mitochondrial DNA sequences alongside those from modern giant pandas, as well as from other members of the bear family (Ursidae. Phylogenetic analyses show that one of the ancient haplotypes is sister to all sampled modern pandas and the second ancient individual is nested among the modern haplotypes, suggesting that genetic diversity may indeed have been higher earlier during the Holocene. Bayesian skyline plot analysis supports this view and indicates a slight decline in female effective population size starting around 6000 years B.P., followed by a recovery around 2000 years ago. Therefore, while the genetic diversity of the giant panda has been affected by recent habitat contraction, it still harbors substantial genetic diversity. Moreover, while its still low population numbers require continued conservation efforts, there seem to be no immediate threats from the perspective of genetic evolutionary potential.

ISP42 (PANDA Tests) - Open Phase Comparison Report

International Nuclear Information System (INIS)

2003-05-01

PANDA is a large-scale facility, which has been constructed at the Paul Scherrer Institute (PSI) for the investigation of both overall dynamic response and the key phenomena of passive containment systems during the long-term heat removal phase for Advanced Light Water Reactors (ALWRs). Using a modular concept with a basic set of cylindrical vessels and connecting piping, the facility can be adapted to simulate different passive containment designs. Following a proposal, the OECD/NEA Committee on the Safety of Nuclear Installations approved, at its meeting on December 3-5, 1997, a new International Standard Problem (ISP) involving a test in the PANDA facility, based on a recommendation from the Principal Working Group 2 (PWG2) on System Behaviour. The main interest for this ISP is code validation in relation to a range of LWR and advanced LWR (ALWR) (mainly) containment issues that have been designated as important and involving thermalhydraulic phenomena. The ISP-PANDA test for defined six phases (A to F) was performed on 21/22 April 1998. Since the first part of ISP-42 was going to be conducted as a 'double- blind' or 'blind' exercise, the experimental data was locked. The 'blind' phase calculational results compared to experimental data are presented in the report entitled 'ISP-42 (PANDA Tests ) Blind Phase Comparison'. In the second part, the 'open' exercise has been conducted by providing the ISP-42 PANDA test data to the participants and by performing post-test analysis. The results of the 'open' phase are presented in the present report. 'Open' phase submissions, comparisons, and analyses for ISP-42 are based on the outcome of the results presented in the 'blind' phase report of ISP-42. The experimental data was distributed to all ISP-42 participants for their post-test calculations, 20 June 2000. 'Open' phase analyses of some of the ISP-42 participants, were completely received by the end of January 2001. There were 27 new submissions for different phases

New physics and technical challenges of anti PANDA

Energy Technology Data Exchange (ETDEWEB)

Gianotti, P. [LNF, Frascati (Italy)

2007-03-15

An antiproton beam of unprecedented intensity and quality will soon be available at the HESR machine foreseen for the new FAIR accelerator complex of Darmstadt. This new facility, together with a properly designed new detector (anti PANDA), will be the ideal environment to study fundamental questions of hadron and nuclear physics and to carry out precise tests of the strong interaction. (orig.)

Prolonged transition time between colostrum and mature milk in a bear, the giant panda, Ailuropoda melanoleuca

Science.gov (United States)

Griffiths, Kate; Hou, Rong; Wang, Hairui; Zhang, Zhihe; Zhang, Liang; Zhang, Tong; Watson, David G.; Burchmore, Richard J. S.; Loeffler, I. Kati; Kennedy, Malcolm W.

2015-01-01

Bears produce the most altricial neonates of any placental mammal. We hypothesized that the transition from colostrum to mature milk in bears reflects a temporal and biochemical adaptation for altricial development and immune protection. Comparison of bear milks with milks of other eutherians yielded distinctive protein profiles. Proteomic and metabolomic analysis of serial milk samples collected from six giant pandas showed a prolonged transition from colostrum to main-phase lactation over approximately 30 days. Particularly striking are the persistence or sequential appearance of adaptive and innate immune factors. The endurance of immunoglobulin G suggests an unusual duration of trans-intestinal absorption of maternal antibodies, and is potentially relevant to the underdeveloped lymphoid system of giant panda neonates. Levels of certain milk oligosaccharides known to exert anti-microbial activities and/or that are conducive to the development of neonatal gut microbiomes underwent an almost complete changeover around days 20–30 postpartum, coincident with the maturation of the protein profile. A potential metabolic marker of starvation was detected, the prominence of which may reflect the natural postpartum period of anorexia in giant panda mothers. Early lactation in giant pandas, and possibly in other ursids, appears to be adapted for the unique requirements of unusually altricial eutherian neonates. PMID:26587250

Non-invasive monitoring of reproductive and stress hormones in the endangered red panda (Ailurus fulgens fulgens).

Science.gov (United States)

Beaulah Budithi, Neema Raja; Kumar, Vinod; Yalla, Suneel Kumar; Rai, Upashna; Umapathy, Govindhaswamy

2016-09-01

The red panda (Ailurus fulgens fulgens) is classified as endangered due to its declining population, habitat fragmentation and poaching. Efforts are being made to breed them in captivity as part of nationwide conservation breeding program. This study aimed to standardize Enzyme immunoassays (EIAs) to monitor reproductive (Progesterone metabolite, Testosterone) and stress hormone (Cortisol) in red panda. For this purpose, we collected 1471 faecal samples from four females and one male over a period of one year from Padmaja Naidu Himalayan Zoological Park, Darjeeling, India. HPLC confirmed the presence of immunoreactive 5α-pregnan-3α-ol-20-one, testosterone and cortisol metabolites in faecal samples. Using 5α-pregnan-3α-ol-20-one EIA, we were able to monitor reproduction and detect pregnancy in one of the females, which successfully conceived and delivered during the study period. We were also able to monitor testosterone and cortisol in faecal samples of the red panda. Faecal testosterone levels were found in higher concentration in breeding season than in non-breeding season. Faecal cortisol concentrations showed a negative relationship with ambient temperature and peaked during winter months in all animals. Standardization of EIAs and faecal hormone monitoring would facilitate red panda conservation breeding programs in India and elsewhere. Copyright © 2016 Elsevier B.V. All rights reserved.

Prolonged transition time between colostrum and mature milk in a bear, the giant panda, Ailuropoda melanoleuca.

Science.gov (United States)

Griffiths, Kate; Hou, Rong; Wang, Hairui; Zhang, Zhihe; Zhang, Liang; Zhang, Tong; Watson, David G; Burchmore, Richard J S; Loeffler, I Kati; Kennedy, Malcolm W

2015-10-01

Bears produce the most altricial neonates of any placental mammal. We hypothesized that the transition from colostrum to mature milk in bears reflects a temporal and biochemical adaptation for altricial development and immune protection. Comparison of bear milks with milks of other eutherians yielded distinctive protein profiles. Proteomic and metabolomic analysis of serial milk samples collected from six giant pandas showed a prolonged transition from colostrum to main-phase lactation over approximately 30 days. Particularly striking are the persistence or sequential appearance of adaptive and innate immune factors. The endurance of immunoglobulin G suggests an unusual duration of trans-intestinal absorption of maternal antibodies, and is potentially relevant to the underdeveloped lymphoid system of giant panda neonates. Levels of certain milk oligosaccharides known to exert anti-microbial activities and/or that are conducive to the development of neonatal gut microbiomes underwent an almost complete changeover around days 20-30 postpartum, coincident with the maturation of the protein profile. A potential metabolic marker of starvation was detected, the prominence of which may reflect the natural postpartum period of anorexia in giant panda mothers. Early lactation in giant pandas, and possibly in other ursids, appears to be adapted for the unique requirements of unusually altricial eutherian neonates.

AFRONTAMIENTO FAMILIAR ANTE LA PRIMERA CRISIS DEL PACIENTE PSIQUIATRICO DEL HOSPITAL MENTAL RUDESINDO SOTO EN EL SEGUNDO SEMESTRE DE 2004

Directory of Open Access Journals (Sweden)

Luz Paola Morales-Contreras

2005-12-01

Full Text Available Con el propósito de determinar el grado de afrontamiento de la familia del paciente psiquiátrico ante el padecimiento de sus primeras crisis que asisten al Hospital Mental Rudesindo Soto de Cúcuta Norte de Santander, se desarrollo el presente estudio de tipo cuantitativo, descriptivo y de corte transversal. La población de estudio estuvo constituida por 40 cuidadores primarios de los pacientes con primera crisis que ingresaron al Hospital Mental Rudesindo Soto durante el periodo comprendido entre Julio y Octubre de 2004 residentes en Ia ciudad de acutal y su área metropolitana, caracterizados de acuerdo al sexo, edad, parentesco, ocupación y escolaridad, a quienes se aplico el instrumento F-COPES "Escala de Evaluación personal del funcionamiento familiar en situación de crisis", para determinar Ia utilización de los mecanismos de afrontamiento y mecanismo de defensa así como la Búsqueda de redes de apoyo social. De acuerdo al afrontamiento familiar el cuidador primario algunas veces busca redes de apoyo, casi nunca utiliza los mecanismos de defensa y los mecanismos de afrontamiento son utilizados algunas veces. Se concluye principalmente que el grado de afrontamiento de Ia familia del paciente psiquiátrico en su primera crisis es desfavorable.

Calidad De Servicio Asociada A La Satisfacción Del Usuario Externo En El Área De Niños Del Servicio De Medicina Física Del Hospital Regional Lambayeque Chiclayo – 2017

OpenAIRE

Costa Gonzáles, Beatriz Lucciana

2017-01-01

Con el objetivo de determinar la asociación entre la calidad de servicio con la satisfacción del usuario externo en el área de niños del servicio de medicina Física del Hospital Regional Lambayeque, 2017, se realizó el presente estudio de tipo descriptivo, prospectivo, transversal, cuantitativo, con una población de 80 usuarios familiares directos (madres) de niños con rehabilitación y una muestra de 63 usuarios del servicio de fisioterapia y rehabilitación durante Marzo 2017 a Mayo 2017, me...

Feasibility studies for the open-charm production in proton-antiproton reactions for the PANDA experiment

Energy Technology Data Exchange (ETDEWEB)

Vejdani, Solmaz [KVI-CART, University of Groningen (Netherlands); Forschungszentrum Juelich, Juelich (Germany); Collaboration: PANDA-Collaboration

2016-07-01

The PANDA experiment is one of the pillars of the future Facility for Antiproton and Ion Research (FAIR) in Darmstadt, Germany. The PANDA physics program is focused on answering fundamental questions related to Quantum Chromodynamics (QCD), mostly in the non-perturbative energy regime. Spectroscopy exploiting Λc-baryons that are composed of a heavy charm valence quark and two light valence quarks is an integral part of the PANDA physics program. Such systems can systematically provide information on various key features of QCD, such as heavy-quark symmetry, chiral symmetry breaking, and the nature of exotic states. In this work, the experimental feasibility of studying the production mechanisms of associative open-charm baryons in antiproton-proton annihilations is investigated by using Monte Carlo simulations. I present results obtained for the channel p anti p → Λ{sup -}{sub c}Λ{sub c}, highlighting the detector performances (efficiencies and resolutions) and the statistical significance that can be achieved with the foreseen luminosities.

Phenomenological study of exclusive binary light particle production from antiproton-proton annihilation at FAIR/PANDA

Science.gov (United States)

Ying, Wang

2016-08-01

Exclusive binary annihilation reactions induced by antiprotons of momentum from 1.5 to 15 GeV/c can be extensively investigated at FAIR/PANDA [1]. We are especially interested in the channel of charged pion pairs. Whereas this very probable channel constitutes the major background for other processes of interest in the PANDA experiment, it carries unique physical information on the quark content of proton, allowing to test different models (quark counting rules, statistical models,..). To study the binary reactions of light meson formation, we are developing an effective Lagrangian model based on Feynman diagrams which takes into account the virtuality of the exchanged particles. Regge factors [2] and form factors are introduced with parameters which may be adjusted on the existing data. We present preliminary results of our formalism for different reactions of light meson production leading to reliable predictions of cross sections, energy and angular dependencies in the PANDA kinematical range.

Book Reivew: A chance for lasting survival: Ecology and behavior of wild giant pandas

Science.gov (United States)

van Manen, Frank T.

2015-01-01

“If we watch species going extinct in front of us, how useful is that we publish 100 or even 1,000 papers by studying them?” (p. 330). This quote from senior author Pan Wenshi captures an important essence of this book. A translation of a 2001 monograph originally published in Chinese, this volume details the findings of a 15-year research program in the Qinling Mountains by Wenshi and his students. Starting in 1984, this Chinese research team from Peking University was only the second to study free-ranging pandas. This is the remarkable journey of a devoted group of field researchers who helped changed the course of giant panda conservation, events that few conservationists outside of China have been aware of until now.Review info: A chance for lasting survival: Ecology and behavior of wild giant pandas. By Pan Wenshi, Lü Zhi, Zhu Xiaojian, Wang Dajun, Wang Hao, Long Yu, Fu Dali, and Zhou Xin; edited by, William J. McShea, Richard B. Harris, David L. Garshelis, and Wang Dajun, 2014. ISBN: 978-1-935623-17-5, 349pp.

Calidad de las notas de enfermería en los registros clínicos del servicio de hospitalización y emergencia del Hospital de Emergencias Pediátricas Lima 2016

OpenAIRE

Cucho Martínez, Liliana Luz

2016-01-01

El presente estudio titulado “calidad de las notas de enfermería en los registros clínicos del servicio de hospitalización y emergencia del hospital emergencias pediátrica, Lima 2016” tuvo como objetivo general, comparar la calidad de las notas de enfermería en los registros clínicos entre los servicio de hospitalización y emergencia del hospital emergencias pediátricas. El tipo de investigación fue cuantitativo, retrospectivo, de diseño no experimental, de corte transversal...

Design optimization of the PANDA micro-vertex-detector for high performance spectroscopy in the charm quark sector

Energy Technology Data Exchange (ETDEWEB)

Wuerschig, Thomas

2011-07-19

The PANDA experiment is one of the key projects at the future FAIR facility, which is currently under construction at GSI Darmstadt. Measurements will be performed with antiprotons using a fixed-target setup. The main scope of PANDA is the study of the strong interaction in the charm quark sector. Therefore, high precision spectroscopy of hadronic systems in this energy domain is a prerequisite. The Micro-Vertex-Detector (MVD) as innermost part of the tracking system plays an important role to achieve this goal. At present, the PANDA project has exceeded the initial phase of conceptual design studies. Based on these results, an optimization of the individual detector subsystems, and thus also for the MVD, is necessary to continue the overall detector development towards its commissioning. Therefore, a comprehensive and realistic detector model must be developed, which on the one hand fulfils the physics requirements but on the other hand also includes feasible engineering solutions. This task is the main scope of the present work. The outcome of these studies will deliver important contributions to the technical design report for the PANDA MVD, which is the next step towards the final detector assembly. In the first part of this work, main physics aspects of the charm spectroscopy are highlighted and a complete review of the experimental status in this field is given. Afterwards, all relevant details of the PANDA experiment are summarized. The conceptual design and associated hardware developments for the MVD are discussed separately in the following chapters. They deliver basic input for the performed detector optimization, which is presented in the central part. Furthermore, this section describes the development of a comprehensive detector model for the MVD and its introduction into the physics simulation framework of PANDA. The final part contains a compilation of extended simulations with the developed detector model. This includes the determination of basic

Design optimization of the PANDA micro-vertex-detector for high performance spectroscopy in the charm quark sector

International Nuclear Information System (INIS)

Wuerschig, Thomas

2011-01-01

The PANDA experiment is one of the key projects at the future FAIR facility, which is currently under construction at GSI Darmstadt. Measurements will be performed with antiprotons using a fixed-target setup. The main scope of PANDA is the study of the strong interaction in the charm quark sector. Therefore, high precision spectroscopy of hadronic systems in this energy domain is a prerequisite. The Micro-Vertex-Detector (MVD) as innermost part of the tracking system plays an important role to achieve this goal. At present, the PANDA project has exceeded the initial phase of conceptual design studies. Based on these results, an optimization of the individual detector subsystems, and thus also for the MVD, is necessary to continue the overall detector development towards its commissioning. Therefore, a comprehensive and realistic detector model must be developed, which on the one hand fulfils the physics requirements but on the other hand also includes feasible engineering solutions. This task is the main scope of the present work. The outcome of these studies will deliver important contributions to the technical design report for the PANDA MVD, which is the next step towards the final detector assembly. In the first part of this work, main physics aspects of the charm spectroscopy are highlighted and a complete review of the experimental status in this field is given. Afterwards, all relevant details of the PANDA experiment are summarized. The conceptual design and associated hardware developments for the MVD are discussed separately in the following chapters. They deliver basic input for the performed detector optimization, which is presented in the central part. Furthermore, this section describes the development of a comprehensive detector model for the MVD and its introduction into the physics simulation framework of PANDA. The final part contains a compilation of extended simulations with the developed detector model. This includes the determination of basic

Conocimientos y aplicación de normas de bioseguridad del servicio de Ginecoobstetricia del Hospital Alberto Leopoldo Barton Thompson, Callao 2016

OpenAIRE

Salas Zegarra, Rita Maribel

2016-01-01

El objetivo del presente trabajo de investigación es determinar la relación que existe entre los conocimientos de normas de bioseguridad y la aplicación de normas de bioseguridad en el servicio de Ginecoobstetricia en el Hospital Alberto Leopoldo Barton Thompson en el Callao, periodo 2016; la población conformada por los técnicos de enfermería, ginecoobstetrasy obstetras del servicio ginecoobstetricia de 75 trabajadores, la muestra consideró toda la población, en los cuales se ...

Study of preshower in the PANDA target spectrometer

International Nuclear Information System (INIS)

Dutta, Kamal; Kalita, Kushal; Suzuki, K.; Steinschaden, D.; Roy, B.J.

2015-01-01

PANDA (antiProton ANnihilation at DArmstdt) is one of the major projects at FAIR, GSI, Germany. The main objective of this experiment is to study the fundamental questions of hadron physics and QCD in pp¯ annihilation using high intensity cooled anti-proton beams with momenta between 1.5 GeV/c and 15 GeV/c. To achieve high momentum resolution and full solid angle coverage, the PANDA detector is split in to two parts: target spectrometer and forward spectrometer. The target spectrometer is a complex detector consisting of several subsystems surrounding the interaction point. It is surrounded by a 2 T superconducting solenoid magnet. A Micro Vertex Detector (MVD), close to interaction point, detects secondary vertices of D and Hyperon decays. The Straw Tube Tracker (STT) is the central tracking system around the MVD. A cherenkov counter named DIRC (Detection of Internally Reflected Cherenkov light), provides π/K separation for particle momenta up to 3.5 GeV/c. The barrel Time-of-Flight (TOF) detector, consists of plastic scintillator tiles with a time resolution of 100 ps. It is used to identify particles of momentum below cherenkov threshold

Performance of the prototype of the electromagnetic calorimeter for PANDA

NARCIS (Netherlands)

Kavatsyuk, M.; Bremer, D.; Dormenev, V.; Drexler, P.; Eissner, T.; Erni, W.; Guliyev, E.; Hennino, T.; Krusche, B.; Lewandowski, B.; Löhner, H.; Moritz, M.; Novotny, R. W.; Peters, K.; Pouthas, J.; Rosier, P.; Steinacher, M.; Tambave, G.; Wilms, A.

2011-01-01

The PANDA collaboration at FAIR, Germany, will employ antiproton annihilations to investigate yet undiscovered charm-meson states and glueballs. The aim is to study QCD phenomena in the non-perturbative regime and to unravel the origin of hadronic masses. A multi-purpose detector for tracking,

Temporal changes in giant panda habitat connectivity across boundaries of Wolong Nature Reserve, China.

Science.gov (United States)

Viña, Andrés; Bearer, Scott; Chen, Xiaodong; He, Guangming; Linderman, Marc; An, Li; Zhang, Hemin; Ouyang, Zhiyun; Liu, Jianguo

2007-06-01

Global biodiversity loss is largely driven by human activities such as the conversion of natural to human-dominated landscapes. A popular approach to mitigating land cover change is the designation of protected areas (e.g., nature reserves). Nature reserves are traditionally perceived as strongholds of biodiversity conservation. However, many reserves are affected by land cover changes not only within their boundaries, but also in their surrounding areas. This study analyzed the changes in habitat for the giant panda (Ailuropoda melanoleuca) inside Wolong Nature Reserve, Sichuan, China, and in a 3-km buffer area outside its boundaries, through a time series of classified satellite imagery and field observations. Habitat connectivity between the inside and the outside of the reserve diminished between 1965 and 2001 because panda habitat was steadily lost both inside and outside the reserve. However, habitat connectivity slightly increased between 1997 and 2001 due to the stabilization of some panda habitat inside and outside the reserve. This stabilization most likely occurred as a response to changes in socioeconomic activities (e.g., shifts from agricultural to nonagricultural economies). Recently implemented government policies could further mitigate the impacts of land cover change on panda habitat. The results suggest that Wolong Nature Reserve, and perhaps other nature reserves in other parts of the world, cannot be managed as an isolated entity because habitat connectivity declines with land cover changes outside the reserve even if the area inside the reserve is well protected. The findings and approaches presented in this paper may also have important implications for the management of other nature reserves across the world.

Revisión del programa de déficit de somatropina en pediatría en el Hospital Universitario Virgen del Rocío

OpenAIRE

Lavaredas, A.; Puerta, R. de la; Álvarez del Vayo, C.

2013-01-01

Objetivo: Elaborar una revisión del programa de déficit de somatropina aplicado en pediatría en el Hospital Universitario Virgen del Rocío, utilizando dos grupos de pacientes, los diagnosticados con déficit de esta hormona y los nacidos pequeños para edad gestacional, con la intención de evaluar su efectividad en el primer año de tratamiento. Método: Realización de un estudio retrospectivo de la cohorte de pacientes en tratamiento con la hormona del crecimiento bajo los diagnósticos mencionad...

Caracterización del infarto agudo del miocardio en mujeres atendidas en el hospital Ernesto Guevara

Directory of Open Access Journals (Sweden)

Zailit González Cruz

2014-08-01

Full Text Available En Las Tunas han aumentado las cifras de mujeres afectadas por infarto agudo del miocardio (IMA, con una tasa de mortalidad superior a la media nacional. A pesar de ello, no existen estudios publicados que describan el comportamiento de esta entidad en las mujeres tuneras. Se realizó un estudio transversal descriptivo en el servicio de cardiología del hospital provincial de Las Tunas, “Dr. Ernesto Guevara de la Serna”, entre los años 2009 al 2011, con el objetivo de caracterizar el infarto agudo del miocardio en el sexo femenino. La muestra estuvo constituida por 181 mujeres admitidas en el servicio por esta entidad, diagnosticadas según los criterios establecidos. Para el análisis de los resultados se utilizó la estadística descriptiva, con valores absolutos y porcientos. En la muestra de estudio prevaleció el IMA CEST, de topografía anterior y no trombolizado. La disfunción ventricular izquierda constituyó la complicación más frecuente. Predominaron como factores de riesgo asociados la hipertensión arterial, las dislipidemias, el hábito de fumar y la diabetes mellitus.

SciTil Detector for the PANDA experiment at FAIR

Science.gov (United States)

Suzuki, Ken; Gruber, Lukas; Brunner, Stefan; Marton, Johann; Orth, Herbert; Schwarz, Carsten; Scitil/Panda Collaboration

2014-09-01

The PANDA experiment at the Facility for Antiproton and Ion Research (FAIR) is a fixed-target experiment installed in a antiproton storage ring (HESR) in the energy range of 1 GeV to 15 GeV. FAIR is being build on the area of the GSI Helmholtzzentrum für Schwerionenforschung in Darmstadt, Germany. The universal PANDA detector together with the HESR enables to study fundamental questions of hadron and nuclear physics, e.g. gluonic excitations, the physics of strange and charm quarks and nucleon structure. The SciTil detector is a barrel time-of-flight detector and is a relatively new subcomponent to the system. The demand arose in order to provide a securer event tagging at the event rates of 20-100 MHz instantaneous event rate, to improve a particle identification capability of relatively low momentum particles, and to allow a faster track finding with pattern recognition. The beam test of the SciTil prototype detector in January 2014 showed a promising result. We report the status and outlook of the project.

Giant Panda movement patterns in the Foping Nature Reserve, China

NARCIS (Netherlands)

Liu, X.; Skidmore, A.K.; Wang, T.; Yong, Y.; Prins, H.H.T.

2002-01-01

Observing the giant panda (Ailuropoda melanoleuca) in the remote mountains of Foping Nature Reserve (NR), China, is difficult due to the dense vegetation and steep terrain. Radiotracking is an effective way to study this animal and understand its behavior and habitat use. We used radiotracking data

Relación entre satisfacción laboral y amabilidad rasgo del colaborador interno en el hospital Edgardo Rebagliati Martins Lima – Perú

OpenAIRE

Torres Alarcón, Fernando

2015-01-01

Estudia la relación entre Satisfacción Laboral y Amabilidad Rasgo del Colaborador Interno en el Hospital Edgardo Rebagliati Martins, Lima - Perú. Se ha identificado una percepción negativa del asegurado a la calidad de servicio que recibe del colaborador interno. Situación problemática reflejada también en los resultados del estudio con el modelo de SERVQUAL, que concluye, “el paciente del Hospital Rebagliati percibe que el servicio ofrecido por la institución es de baja calidad. Asimismo,...

Área de Arte y Salud del Hospital de Niños Sor María Ludovica de La Plata

OpenAIRE

Iriart Urruty, Andrea

2014-01-01

El Hospital de Niños “Sor María Ludovica” de la ciudad de La Plata, a partir de la firma de la disposición N° 940/13 por parte de la dirección del mismo, funciona el “Área de Arte y Salud” integrada por el Servicio Social, el Servicio de Salud Mental del Hospital, la Biblioteca Ambulante, el Taller de Plástica y Literatura y el Laboratorio de Arte que desarrolla el Grupo La Grieta. Esta área es un espacio institucional abocado a aunar criterios y conjugar inquietudes en torno al papel del ...

Phenological changes in bamboo carbohydrates explain the preference for culm over leaves by giant pandas (Ailuropoda melanoleuca during spring.

Directory of Open Access Journals (Sweden)

Katrina K Knott

Full Text Available Seasonal changes in the foodscape force herbivores to select different plant species or plant parts to meet nutritional requirements. We examined whether the search for calorie-rich carbohydrates explained giant panda's selection for bamboo culm over leaves during spring. Leaves and culms were collected from four Phyllostachys bamboos (P. aurea, P. aureosulcata, P. glauca, and P. nuda once per month over 18-27 months. Monthly changes in annual plant part nutrients were examined, and compared to seasonal foraging behaviors of captive giant pandas. Although total fiber was greater (p<0.0001 in culm (85.6 ± 0.5% than leaves (55.3 ± 0.4% throughout the year, culm fiber was at its lowest in spring (79-85% when culm selection by giant pandas exceeded 70% of their overall diet. Culm starch also was greatest (p = 0.044 during spring (5.5 ± 1.1% and 2.5-fold the percentage of starch in leaves (2.2 ± 0.6%. The free sugars in spring culm consisted of a high proportion of glucose (35% and fructose (47%, whereas sucrose made up 42% of the total free sugar content of spring leaves. Bound sugars in culm consisted of 60% glucose and 38% xylose likely representative of hemicellulose. The concentrations of bound sugars (hemicelluloses in spring culms (543.7 ± 13.0 mg/g was greater (p<0.001 than in leaves (373.0 ± 14.8 mg/g. These data help explain a long-standing question in giant panda foraging ecology: why consume the plant part with the lowest protein and fat during the energetically intensive spring breeding season? Giant pandas likely prefer spring culm that contains abundant mono- and polysaccharides made more bioavailable as a result of reduced fiber content. These data suggest that phenological changes in bamboo plant part nutrition drive foraging decisions by giant pandas.

2 T superconducting detector solenoid for the PANDA target spectrometer

Energy Technology Data Exchange (ETDEWEB)

Efremov, A.A.; Koshurnikov, E.K. [Joint Institute for Nuclear Research, High Energy Physics Laboratory, Joliot-Curie, 6, 141980 Dubna, Moscow Region (Russian Federation); Lobanov, Y.Y. [Joint Institute for Nuclear Research, High Energy Physics Laboratory, Joliot-Curie, 6, 141980 Dubna, Moscow Region (Russian Federation)], E-mail: lobanov@jinr.ru; Makarov, A.F. [Joint Institute for Nuclear Research, High Energy Physics Laboratory, Joliot-Curie, 6, 141980 Dubna, Moscow Region (Russian Federation); Orth, H. [Gesellschaft fuer Schwerionenforschung, Planckstrasse 1, D-64291, Darmstadt (Germany); Sissakian, A.N.; Vodopianov, A.S. [Joint Institute for Nuclear Research, High Energy Physics Laboratory, Joliot-Curie, 6, 141980 Dubna, Moscow Region (Russian Federation)

2008-02-01

This paper describes the JINR design of the large 2 T superconducting solenoid for the target spectrometer of the PANDA experiment at HESR (FAIR, GSI, Darmstadt, Germany). The solenoid coil has an inner radius of 1.08 m and a length of 2.90 m. This solenoid is non-centrally split providing a warm bore of 100 mm in diameter through the coil to accommodate sufficient space for the internal target installations. Maximally stored energy in the windings is 22.3 MJ. All tracking and calorimetric detectors surrounding the target point, with exception of a forward cone of 5{sup 0} opening, are placed inside the lqHe-cryostat. The main features of the design and technique are as follows: a copper stabilizer and soldering technique for the superconducting cable; a stainless steel cryostat; winding technique over a mandrel; coreless type of the coil; low operational current. The details of the PANDA solenoid design including the magnetic field and stress-strain calculations are covered.

Development of DIRC counters for the PANDA experiment at FAIR

International Nuclear Information System (INIS)

Seitz, B.; Bettoni, D.; Branford, D.; Britting, A.; Carassiti, V.; Cecchi, A.; Cowie, E.; Dodokhof, V.Kh.; Dueren, M.; Eyrich, W.; Foehl, K.; Hayrapetyan, A.; Hill, G.; Hoek, M.; Hohler, R.; Kaiser, R.; Keri, T.; Lehmann, A.; Lehmann, D.; Marton, J.

2011-01-01

The PANDA experiment at the planned FAIR facility at GSI, Darmstadt, aims at measuring hadronic final states with unprecedented precision and luminosity. Superior particle identification of charged and neutral particles is mandatory to fulfil PANDA's physics aims. DIRC (Detection of Internally Reflected Cherenkov light) counters are foreseen for charged particle identification. A barrel DIRC will cover the central region while a disc DIRC will provide particle identification in the forward region. Three DIRC concepts differing in the radiator geometry and method for dispersion correction are studied. The barrel DIRC uses a novel imaging system and aims at exploiting a 3D reconstruction to mitigate dispersion effects. Two concepts are investigated for the forward disc DIRC. One concept employs passive dispersion correction and focussing light guides for image reconstruction. Alternatively, time-of-propagation measurements and a wave-length dependent photon detection system are investigated. The three detector designs share common developments such as investigating radiator properties and photon detection systems, and use the same test beam facilities.

Sarcocystis spp. Infection in two Red Panda Cubs (Ailurus fulgens).

Science.gov (United States)

Zoll, W M; Needle, D B; French, S J; Lim, A; Bolin, S; Langohr, I; Agnew, D

2015-01-01

Two neonatal male red panda (Ailurus fulgens) littermates were submitted for necropsy examination. One animal was found dead with no prior signs of illness; the other had a brief history of laboured breathing. Post-mortem examination revealed disseminated protozoal infection. To further characterize the causative agent, transmission electron microscopy (TEM), immunohistochemistry (IHC), polymerase chain reaction (PCR) and amplification and nucleic acid sequencing were performed. IHC was negative for Toxoplasma gondii and Neospora caninum, but was positive for a Sarcocystis spp. TEM of cardiac muscle and lung revealed numerous intracellular apicomplexan protozoa within parasitophorous vacuoles. PCR and nucleic acid sequencing of partial 18S rRNA and the internal transcribed spacer (ITS)-1 region confirmed a Sarcocystis spp. that shared 99% sequence homology to Sarcocystis neurona and Sarcocystis dasypi. This represents the first report of sarcocystosis in red pandas. The histopathological, immunohistochemical, molecular and ultrastructural findings are supportive of vertical transmission resulting in fatal disseminated disease. Copyright © 2015 Elsevier Ltd. All rights reserved.

PanDA: Exascale Federation of Resources for the ATLAS Experiment

CERN Document Server

Barreiro Megino, Fernando Harald; The ATLAS collaboration; Maeno, Tadashi; Wenaus, Torre; Nilsson, Paul; Klimentov, Alexei; Oleynik, Danila; Panitkin, Sergey; Petrosyan, Artem; Vukotic, Ilija

2015-01-01

After a scheduled maintenance and upgrade period, the world’s largest and most powerful machine - the Large Hadron Collider(LHC) - is about to enter its second run at unprecedented energies. In order to exploit the scientific potential of the ma- chine, the experiments at the LHC face computational challenges with enormous data volumes that need to be analysed by thousand of physics users and compared to simulated data. Given diverse funding constraints, the computational resources for the LHC have been deployed in a worldwide mesh of data centres, connected to each other through Grid technologies. The PanDA (Production and Distributed Analysis) system was developed in 2005 for the ATLAS experiment on top of this heterogeneous infrastructure to seamlessly integrate the computational resources and give the users the feeling of a unique system. Since its origins, PanDA has evolved together with upcoming computing paradigms in and outside HEP, such as changes in the networking model, cloud computing and HPC. I...

Síndrome de Burnout en estudiantes de internado del Hospital Universidad del Norte

Directory of Open Access Journals (Sweden)

Mariela Borda Pérez

2007-01-01

Full Text Available Objetivo: Establecer el comportamiento y los factores de riesgo asociados al Síndrome de Burnout (SB en estudiantes de último año de medicina en en el internado rotatorio I y II, en el Hospital Universidad del Norte en el 2006. Métodos: Estudio descriptivo de la población de 55 estudiantes de último año en internado rotatorio I y II de ambos sexos. Se empleó encuesta autodiligenciada anónima sobre características sociodemográficas, laborales y la escala de Maslach. Se procesaron y presentaron los datos utilizando SPSS. Se efectuó análisis univariado y bivariado para establecer tendencia a la asociación entre la variable dependiente SB y las independientes mediante Chi cuadrado y valor de p <0.05. Resultados: La prevalencia global del SB es de 9.1%; la distribución según dimensiones del SB es: agotamiento emocional: 41.8%, despersonalización: 30.9%, realización personal baja: 12.7%. Se encontró significancia estadística entre SB y relaciones con el equipo de trabajo; asimismo, hubo relación de esta variable con el grado de agotamiento emocional y de realización personal y entre la presencia de hijos y el grado de agotamiento emocional. Conclusiones: El SB es bajo en los internos. Se encontró tendencia a la asociación entre las relaciones con el equipo de trabajo y los grados de agotamiento emocional y de realización personal.

Panda-Monium at the Library: 1995 Arizona Reading Program.

Science.gov (United States)

Arizona State Dept. of Library, Archives and Public Records, Phoenix.

Panda bears are the theme of this guide which includes many reading-related activities, crafts, and programs on a broad range of topics, and which can be expanded to other theme approaches such as endangered species, bears in general, and the concept of black and white. The program begins with a general definition and discussion of goals,…

Gestión de la bioseguridad hospitalaria en los servicios de la salud. Estudio realizado en el servicio de emergencias urgencias del Hospital del IESS "Dr. Teodoro Maldonado Carbo", en el año 2014.

OpenAIRE

Macías Carpio, Mireya Martha

2015-01-01

La investigación presente, gestión de la bioseguridad hospitalaria en el Servicio de Emergencia del Hospital Dr. Teodoro Maldonado Carbo, tiene como objetivo analizar el cumplimiento de las medidas de bioseguridad del personal de la salud y de limpieza, según la gestión actual de manejo de la bioseguridad del hospital. Para cumplir con el objetivo, se empleó la observación directa del sitio, la entrevista al Comité de Control de Infecciones y las encuestas al personal. Durante el estudi...

Discovery and validation of the tumor-suppressive function of long noncoding RNA PANDA in human diffuse large B-cell lymphoma through the inactivation of MAPK/ERK signaling pathway.

Science.gov (United States)

Wang, Yingjun; Zhang, Mingzhi; Xu, Huanan; Wang, Yifei; Li, Zhaoming; Chang, Yu; Wang, Xinhuan; Fu, Xiaorui; Zhou, Zhiyuan; Yang, Siyuan; Wang, Bei; Shang, Yufeng

2017-09-22

Diffuse large B-cell lymphoma (DLBCL) is one of the leading causes of cancer-related mortality, and responds badly to existing treatment. Thus, it is of urgent need to identify novel prognostic markers and therapeutic targets of DLBCL. Recent studies have shown that long non-coding RNAs (lncRNAs) play an important role in the development of cancer. By using the next generation HiSeq sequencing assay, we determined lncRNAs exhibiting differential expression between DLBCL patients and healthy controls. Then, RT-qPCR was performed for identification in clinical samples and cell materials, and lncRNA PANDA was verified to be down-regulated in DLBCL patients and have considerable diagnostic potential. In addition, decreased serum PANDA level was correlated to poorer clinical outcome and lower overall survival in DLBCL patients. Subsequently, we determined the experimental role of lncRNA PANDA in DLBCL progression. Luciferase reporter assay and chromatin immunoprecipitation assay suggested that lncRNA PANDA was induced by p53 and p53 interacts with the promoter region of PANDA. Cell functional assay further indicated that PANDA functioned as a tumor suppressor gene through the suppression of cell growth by a G0/G1 cell cycle arrest in DLBCL. More importantly, Cignal Signal Transduction Reporter Array and western blot assay showed that lncRNA PANDA inactivated the MAPK/ERK signaling pathway. In conclusion, our integrated approach demonstrates that PANDA in DLBCL confers a tumor suppressive function through inhibiting cell proliferation and silencing MAPK/ERK signaling pathway. Thus, PANDA may be a promising therapeutic target for patients with DLBCL.

The PANDA physics program: Strangeness and more

Energy Technology Data Exchange (ETDEWEB)

Iazzi, Felice, E-mail: felice.iazzi@polito.it [INFN-Sezione di Torino, Turin (Italy); Politecnico di Torino, Turin (Italy); Collaboration: PANDA Collaboration

2016-06-21

The physics program of the PANDA experiment at FAIR is illustrated, with a particular attention to the planned activity in the field of the doubly strange systems. The investigation of these systems can help, among others, to shed light on the role of the hyperons in the composition of the neutron stars. The great advantages that can be reached in the field of the charmed systems and nucleon structure by using high quality and intense antiproton beams are also recalled.

The PANDA physics program: Strangeness and more

International Nuclear Information System (INIS)

Iazzi, Felice

2016-01-01

The physics program of the PANDA experiment at FAIR is illustrated, with a particular attention to the planned activity in the field of the doubly strange systems. The investigation of these systems can help, among others, to shed light on the role of the hyperons in the composition of the neutron stars. The great advantages that can be reached in the field of the charmed systems and nucleon structure by using high quality and intense antiproton beams are also recalled.

Taxonomy Icon Data: giant panda [Taxonomy Icon

Lifescience Database Archive (English)

Full Text Available giant panda Ailuropoda melanoleuca Chordata/Vertebrata/Mammalia/Theria/Eutheria/Carnivora Ailuropoda_mela...noleuca_L.png Ailuropoda_melanoleuca_NL.png Ailuropoda_melanoleuca_S.png Ailuropoda_mela...noleuca_NS.png http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Ailuropoda+melanoleuca&t=L http://bioscien...cedbc.jp/taxonomy_icon/icon.cgi?i=Ailuropoda+melanoleuca&t=NL http://biosciencedb...c.jp/taxonomy_icon/icon.cgi?i=Ailuropoda+melanoleuca&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Ailuropoda+melanoleuca&t=NS ...

Patterns of genetic differentiation at MHC class I genes and microsatellites identify conservation units in the giant panda.

Science.gov (United States)

Zhu, Ying; Wan, Qiu-Hong; Yu, Bin; Ge, Yun-Fa; Fang, Sheng-Guo

2013-10-22

Evaluating patterns of genetic variation is important to identify conservation units (i.e., evolutionarily significant units [ESUs], management units [MUs], and adaptive units [AUs]) in endangered species. While neutral markers could be used to infer population history, their application in the estimation of adaptive variation is limited. The capacity to adapt to various environments is vital for the long-term survival of endangered species. Hence, analysis of adaptive loci, such as the major histocompatibility complex (MHC) genes, is critical for conservation genetics studies. Here, we investigated 4 classical MHC class I genes (Aime-C, Aime-F, Aime-I, and Aime-L) and 8 microsatellites to infer patterns of genetic variation in the giant panda (Ailuropoda melanoleuca) and to further define conservation units. Overall, we identified 24 haplotypes (9 for Aime-C, 1 for Aime-F, 7 for Aime-I, and 7 for Aime-L) from 218 individuals obtained from 6 populations of giant panda. We found that the Xiaoxiangling population had the highest genetic variation at microsatellites among the 6 giant panda populations and higher genetic variation at Aime-MHC class I genes than other larger populations (Qinling, Qionglai, and Minshan populations). Differentiation index (FST)-based phylogenetic and Bayesian clustering analyses for Aime-MHC-I and microsatellite loci both supported that most populations were highly differentiated. The Qinling population was the most genetically differentiated. The giant panda showed a relatively higher level of genetic diversity at MHC class I genes compared with endangered felids. Using all of the loci, we found that the 6 giant panda populations fell into 2 ESUs: Qinling and non-Qinling populations. We defined 3 MUs based on microsatellites: Qinling, Minshan-Qionglai, and Daxiangling-Xiaoxiangling-Liangshan. We also recommended 3 possible AUs based on MHC loci: Qinling, Minshan-Qionglai, and Daxiangling-Xiaoxiangling-Liangshan. Furthermore, we recommend

Determination of Baylisascaris schroederi infection in wild giant pandas by an accurate and sensitive PCR/CE-SSCP method.

Directory of Open Access Journals (Sweden)

Wenping Zhang

Full Text Available It has been recognized that other than habitat loss, degradation and fragmentation, the infection of the roundworm Baylisascaris schroederi (B. schroederi is one of the major causes of death in wild giant pandas. However, the prevalence and intensity of the parasite infection has been inconsistently reported through a method that uses sedimentation-floatation followed by a microscope examination. This method fails to accurately determine infection because there are many bamboo residues and/or few B. schroederi eggs in the examined fecal samples. In the present study, we adopted a method that uses PCR and capillary electrophoresis combined with a single-strand conformation polymorphism analysis (PCR/CE-SSCP to detect B. schroederi infection in wild giant pandas at a nature reserve, and compared it to the traditional microscope approach. The PCR specifically amplified a single band of 279-bp from both fecal samples and positive controls, which was confirmed by sequence analysis to correspond to the mitochondrial COII gene of B. schroederi. Moreover, it was demonstrated that the amount of genomic DNA was linearly correlated with the peak area of the CE-SSCP analysis. Thus, our adopted method can reliably detect the infectious prevalence and intensity of B. schroederi in wild giant pandas. The prevalence of B. schroederi was found to be 54% in the 91 fecal samples examined, and 48% in the fecal samples of 31 identified individual giant pandas. Infectious intensities of the 91 fecal samples were detected to range from 2.8 to 959.2 units/gram, and from 4.8 to 959.2 units/gram in the fecal samples of the 31 identified giant pandas. For comparison, by using the traditional microscope method, the prevalence of B. schroederi was found to be only 33% in the 91 fecal samples, 32% in the fecal samples of the 31 identified giant pandas, and no reliable infectious intensity was observed.

Rotatividade da equipe de enfermagem: estudo em hospital-escola Rotación del equipo de enfermería: estudio en un hospital universitario Nursing staff turnover: a study at a school-hospital

Directory of Open Access Journals (Sweden)

Felícia Hiromi Nomura

2005-10-01

Full Text Available Este estudo é do tipo exploratório-descritivo de caráter retrospectivo, e teve o objetivo de mensurar e comparar as taxas de rotatividade da equipe de enfermagem do Hospital Universitário da Universidade de São Paulo. A população constituiu-se de 255 trabalhadores de enfermagem - 78 enfermeiras, 20 técnicos e 156 auxiliares que se desligaram do hospital no período de 1997 a 2000. Para mensurar a rotatividade foram utilizados indicadores globais, taxa de admissão e desligamento, taxa líquida de substituição e taxa de variação do número das posições de trabalho. A análise quantitativa dos dados permitiu concluir que a equipe de enfermagem, nesse hospital, apresenta baixa rotatividade.Este estudio es de tipo exploratorio-descriptivo de carácter retrospectivo y tuvo como objetivo medir y comparar las tasas de rotación del equipo de enfermería del Hospital Universitario de la Universidad de São Paulo. La población se constituyó de 255 trabajadores de enfermería - 78 enfermeras, 20 técnicos y 156 auxiliares que salieron del hospital en el período de 1997 a 2000. Para la mensuración de la rotación se utilizó indicadores globales, tasa de admisión y renuncia, tasa líquida de substitución y tasa de variación. El desarrollo de esta investigación permitió concluir que el equipo de enfermería en ese hospital presenta baja rotación.The goal of this exploratory-descriptive study was to measure and compare nursing staff turnover levels at the University Hospital of São Paulo University. The population consisted of 255 nursing workers - 78 nurses, 20 technicians and 156 auxiliaries - who resigned from the hospital between 1997 and 2000. Turnover levels were measured by means of global indicators, admission and resignation, net replacement on the job and variation rates. Quantitative data analysis indicated a low nursing staff turnover rate at this hospital.

Políticas nacionales de salud y decisiones locales en México: el caso del Hospital Mixto de Cuetzalan, Puebla National health policies and local decisions in Mexico: the case of an intercultural hospital in Cuetzalan, Puebla

Directory of Open Access Journals (Sweden)

María Beatriz Duarte-Gómez

2004-10-01

Full Text Available OBJETIVO: Identificar la evolución del hospital del municipio de Cuetzalan a partir de la influencia que diversos elementos del contexto nacional e internacional han tenido sobre ella. MATERIAL Y MÉTODOS: Estudio de caso, realizado en 2000 y 2001 sobre los Hospitales Mixtos en México -el de Cuetzalan, en el estado de Puebla, y el de Jesús María, en el estado de Nayarit-. Durante el trabajo de campo se obtuvo información a través de 72 entrevistas semiestructuradas con terapeutas alópatas e indígenas del hospital y con directivos de los diferentes niveles del sistema de salud. Además, se hizo una revisión documental, tanto de las políticas nacionales de salud para pueblos indígenas, como de las indigenistas, para relacionarlas con las cinco etapas organizacionales del hospital. Además de la autorización de los directivos estatales para el estudio, se pidió el consentimiento informado de los entrevistados. RESULTADOS: El hospital fue creado en 1958 por la Secretaría de Salud con carácter biomédico, acorde con el indigenismo integracionista de la época, y continuó con ese carácter durante la administración inicial del Instituto Nacional Indigenista. Pero las nuevas tendencias del indigenismo participativo y la sensibilidad y creatividad de algunos funcionarios del Instituto, sumadas a estrategias internacionales para lograr una mayor integración de las culturas indígenas, impulsaron su transformación, en 1990, en Hospital Mixto (que ofrecía las dos medicinas, la indígena y la alopática con proyección regional. En la devolución del hospital a la Secretaría Estatal de Salud en 2000, que causó retrocesos temporales en el carácter mixto del hospital, primaron los criterios financieros sobre los socioculturales, mientras que en la actual versión del hospital como Hospital Integral con Medicina Tradicional influyeron, además de la iniciativa de funcionarios estatales, el reposicionamiento político de los indígenas en

Evaluación del manejo del dolor en el area de gestión clínica de medicina interna del hospital de Cabueñes (Gijón)

OpenAIRE

Nekotxea Lezaun, Kenya

2015-01-01

Estudio descriptivo, observacional, transversal y retrospectivo llevado a cabo en Asturias, en el Área V de Salud, concretamente en el Área de Gestión Clínica de Medicina Interna del Hospital de Cabueñes de Gijón.

Track propagation methods for the correlation of charged tracks with clusters in the calorimeter of the bar PANDA experiment

Science.gov (United States)

Nasawasd, T.; Simantathammakul, T.; Herold, C.; Stockmanns, T.; Ritman, J.; Kobdaj, C.

2018-02-01

To classify clusters of hits in the electromagnetic calorimeter (EMC) of bar PANDA (antiProton ANnihilation at DArmstadt), one has to match these EMC clusters with tracks of charged particles reconstructed from hits in the tracking system. Therefore the tracks are propagated to the surface of the EMC and associated with EMC clusters which are nearby and below a cut parameter. In this work, we propose a helix propagator to extrapolate the track from the Straw Tube Tracker (STT) to the inner surface of the EMC instead of the GEANE propagator which is already embedded within the PandaRoot computational framework. The results for both propagation methods show a similar quality, with a 30% gain in CPU time when using the helix propagator. We use Monte-Carlo truth information to compare the particle ID of the EMC clusters with the ID of the extrapolated points, thus deciding upon the correctness of the matches. By varying the cut parameter as a function of transverse momentum and particle type, our simulations show that the purity can be increased by 3-5% compared to the default value which is a constant cut in the bar PANDA simulation framework PandaRoot.

Optical properties of the PANDA barrel DIRC radiator bars

Energy Technology Data Exchange (ETDEWEB)

Kalicy, Grzegorz; Krebs, Marvin; Peters, Klaus [GSI, Darmstadt (Germany); Goethe Universitaet, Frankfurt (Germany); Schwarz, Carsten; Schwiening, Jochen [GSI, Darmstadt (Germany); Collaboration: PANDA-Collaboration

2015-07-01

The PANDA experiment at the Facility for Antiproton and Ion Research in Europe (FAIR) at GSI, Darmstadt, will study fundamental questions of hadron physics and QCD. A fast focusing DIRC (Detection of Internally Reflected Cherenkov light) counter will provide hadronic particle identification (PID) in the barrel region of the PANDA detector. To meet the PID requirements, the Barrel DIRC has to provide precise measurements of the Cherenkov angle, which is conserved for Cherenkov photons propagating through the radiator by total internal reflection. The radiators, rectangular bars made from fused silica, have to fulfill very strict optical and mechanical requirements. This includes the squareness and parallelism of the sides of the bars, sharp corners, and a very smooth surface polish, ensuring that the Cherenkov photons reach the optical sensors without angular distortions. Currently the Barrel DIRC is at the final design stage and several different bar shapes and fabrication methods are being considered for the final detector. An optical setup, consisting of a computer-controlled positioning and a multi-wavelength laser system, is used to evaluate the radiator bars to obtain critical values like transmittance and reflectivity. The current results and techniques are presented on this poster.

Numerical investigations of the WASA pellet target operation and proposal of a new technique for the PANDA pellet target

International Nuclear Information System (INIS)

Varentsov, Victor L.

2011-01-01

The conventional nozzle vibration technique of the hydrogen micro-droplet generation that is supposed to be used for internal pellet target production for the future PANDA experiment at the international FAIR facility in Darmstadtfor is described. The operation of this technique has been investigated by means of detailed computer simulations. Results of calculations for the geometry and operation conditions of the WASA pellet generator are presented and discussed. We have found that for every given pellet size, there is a set of operation parameters where the efficiency of the WASA hydrogen pellet target operation is considerably increased. Moreover, the results of presented computer simulations clearly show that the future PANDA pellet target setup can be realized with the use of much smaller (and cheaper) vacuum pumps than those used at present in the WASA hydrogen pellet target. To qualitatively improve the PANDA hydrogen pellet target performance we have proposed the use of a novel flow focusing method of Ganan-Calvo and Barreto (1997,1999) combined with the use of conventional vacuum injection capillary. Possibilities of this approach for the PANDA pellet target production have been also explored by means of computer simulations. The results of these simulations show that the use of this new approach looks very promising and in particular, there is no need here to use of expensive ultra-pure hydrogen to prevent nozzle clogging or freezing up due to impurities and it will allow simple, fast, smooth and a wide range of change of pellet sizes in accordance with requirements of different experiments at the PANDA detector. In this article we also propose and describe the idea of a new technique to break up a liquid microjet into microdroplets using a process of liquid jet evaporation under pulsed laser beam irradiation. This technique should be experimentally checked before it may be used in the design of the future PANDA pellet target setup.

Numerical investigations of the WASA pellet target operation and proposal of a new technique for the PANDA pellet target

Energy Technology Data Exchange (ETDEWEB)

Varentsov, Victor L., E-mail: v.varentsov@gsi.de [Institute for Theoretical and Experimental Physics, B. Cheremushkinskaya 25, 117218 Moscow (Russian Federation)

2011-08-01

The conventional nozzle vibration technique of the hydrogen micro-droplet generation that is supposed to be used for internal pellet target production for the future PANDA experiment at the international FAIR facility in Darmstadtfor is described. The operation of this technique has been investigated by means of detailed computer simulations. Results of calculations for the geometry and operation conditions of the WASA pellet generator are presented and discussed. We have found that for every given pellet size, there is a set of operation parameters where the efficiency of the WASA hydrogen pellet target operation is considerably increased. Moreover, the results of presented computer simulations clearly show that the future PANDA pellet target setup can be realized with the use of much smaller (and cheaper) vacuum pumps than those used at present in the WASA hydrogen pellet target. To qualitatively improve the PANDA hydrogen pellet target performance we have proposed the use of a novel flow focusing method of Ganan-Calvo and Barreto (1997,1999) combined with the use of conventional vacuum injection capillary. Possibilities of this approach for the PANDA pellet target production have been also explored by means of computer simulations. The results of these simulations show that the use of this new approach looks very promising and in particular, there is no need here to use of expensive ultra-pure hydrogen to prevent nozzle clogging or freezing up due to impurities and it will allow simple, fast, smooth and a wide range of change of pellet sizes in accordance with requirements of different experiments at the PANDA detector. In this article we also propose and describe the idea of a new technique to break up a liquid microjet into microdroplets using a process of liquid jet evaporation under pulsed laser beam irradiation. This technique should be experimentally checked before it may be used in the design of the future PANDA pellet target setup.

VHDL Implementation of Feature-Extraction Algorithm for the PANDA Electromagnetic Calorimeter

NARCIS (Netherlands)

Kavatsyuk, M.; Guliyev, E.; Lemmens, P. J. J.; Löhner, H.; Tambave, G.

2010-01-01

The feature-extraction algorithm, developed for the digital front-end electronics of the electromagnetic calorimeter of the PANDA detector at the future FAIR facility, is implemented in VHDL for a commercial 16 bit 100 MHz sampling ADC. The use of modified firmware with the running on-line

VHDL implementation of feature-extraction algorithm for the PANDA electromagnetic calorimeter

NARCIS (Netherlands)

Guliyev, E.; Kavatsyuk, M.; Lemmens, P. J. J.; Tambave, G.; Löhner, H.

2012-01-01

A simple, efficient, and robust feature-extraction algorithm, developed for the digital front-end electronics of the electromagnetic calorimeter of the PANDA spectrometer at FAIR, Darmstadt, is implemented in VHDL for a commercial 16 bit 100 MHz sampling ADC. The source-code is available as an

Technical Design Report for the PANDA Solenoid and Dipole Spectrometer Magnets

NARCIS (Netherlands)

Erni, W.; Keshelashvili, I; Krusche, B.

2009-01-01

This document is the Technical Design Report covering the two large spectrometer magnets of the PANDA detector set-up. It shows the conceptual design of the magnets and their anticipated performance. It precedes the tender and procurement of the magnets and, hence, is subject to possible

cDNA, genomic sequence cloning and overexpression of ribosomal protein S25 gene (RPS25) from the Giant Panda.

Science.gov (United States)

Hao, Yan-Zhe; Hou, Wan-Ru; Hou, Yi-Ling; Du, Yu-Jie; Zhang, Tian; Peng, Zheng-Song

2009-11-01

RPS25 is a component of the 40S small ribosomal subunit encoded by RPS25 gene, which is specific to eukaryotes. Studies in reference to RPS25 gene from animals were handful. The Giant Panda (Ailuropoda melanoleuca), known as a "living fossil", are increasingly concerned by the world community. Studies on RPS25 of the Giant Panda could provide scientific data for inquiring into the hereditary traits of the gene and formulating the protective strategy for the Giant Panda. The cDNA of the RPS25 cloned from Giant Panda is 436 bp in size, containing an open reading frame of 378 bp encoding 125 amino acids. The length of the genomic sequence is 1,992 bp, which was found to possess four exons and three introns. Alignment analysis indicated that the nucleotide sequence of the coding sequence shows a high homology to those of Homo sapiens, Bos taurus, Mus musculus and Rattus norvegicus as determined by Blast analysis, 92.6, 94.4, 89.2 and 91.5%, respectively. Primary structure analysis revealed that the molecular weight of the putative RPS25 protein is 13.7421 kDa with a theoretical pI 10.12. Topology prediction showed there is one N-glycosylation site, one cAMP and cGMP-dependent protein kinase phosphorylation site, two Protein kinase C phosphorylation sites and one Tyrosine kinase phosphorylation site in the RPS25 protein of the Giant Panda. The RPS25 gene was overexpressed in E. coli BL21 and Western Blotting of the RPS25 protein was also done. The results indicated that the RPS25 gene can be really expressed in E. coli and the RPS25 protein fusioned with the N-terminally his-tagged form gave rise to the accumulation of an expected 17.4 kDa polypeptide. The cDNA and the genomic sequence of RPS25 were cloned successfully for the first time from the Giant Panda using RT-PCR technology and Touchdown-PCR, respectively, which were both sequenced and analyzed preliminarily; then the cDNA of the RPS25 gene was overexpressed in E. coli BL21 and immunoblotted, which is the first

Prevalencia del síndrome del quemado y estudio de los factores asociados en los trabajadores de un hospital comarcal

Directory of Open Access Journals (Sweden)

Pera G.

2002-01-01

Full Text Available Objetivo: El síndrome del quemado o de burnout es un tipo de estrés laboral que puede tener repercusiones psicosomáticas, conductuales, emocionales, familiares y sociales, y que puede ser motivo de absentismo laboral y de bajo rendimiento en el trabajo. El objetivo de este trabajo es conocer la prevalencia del síndrome del quemado entre los trabajadores de un hospital comarcal, así como conocer las características personales y laborales que se asocian a dicho síndrome. Métodos: Se diseñó un estudio observacional transversal en el que se seleccionó una muestra aleatoria, estratificada por categoría profesional, de 300 trabajadores a los que se les administró el Maslach Burnout Inventory para medir el grado de burnout. Este cuestionario consta de tres subescalas: el cansancio emocional, la despersonalización y la realización personal. Resultados: El 13,9% de los entrevistados presentó un grado elevado de burnout para el cansancio emocional, el 11,1% para la despersonalización y el 6,6% para la realización personal. Ninguno de los entrevistados obtuvo puntuaciones elevadas en las tres escalas a la vez, mientras que un 27% presentó un grado alto de burnout en al menos una de las tres escalas. En el análisis multivariante la categoría profesional y el sexo se asociaron de forma estadísticamente significativa con un alto grado de burnout. Conclusiones: La prevalencia de síndrome del quemado en el hospital de Mataró es relativamente baja y se asocia al género y la categoría profesional.

A high resolution germanium detector array for hypernuclear studies at PANDA

Energy Technology Data Exchange (ETDEWEB)

Bleser, Sebastian; Sanchez Lorente, Alicia; Steinen, Marcell [Helmholtz-Institut Mainz (Germany); Gerl, Juergen; Kojouharova, Jasmina; Kojouharov, Ivan [GSI Darmstadt (Germany); Iazzi, Felice [Politecnico, Torino (Italy); INFN, Torino (Italy); Pochodzalla, Josef; Rittgen, Kai; Sahin, Cihan [Institute for Nuclear Physics, JGU Mainz (Germany)

2014-07-01

The PANDA experiment, planned at the FAIR facility in Darmstadt, aims at the high resolution γ-spectroscopy of double Λ hypernuclei. For this purpose a devoted detector setup is required, consisting of a primary nuclear target, an active secondary target and a germanium detector array for the γ-spectroscopy. Due to the limited space within the PANDA detector a compact design is required. In particular the conventional LN{sub 2} cooling system must be replaced by an electro mechanical device and a new arrangement of the crystals is needed. This presentation shows the progress in the development of the germanium detectors. First results of in-beam measurements at COSY with a new electro mechanically cooled single crystal prototype are presented. Digital pulse shape analysis is used to disentangle pile up events due to the high event rate. This analysis technique also allows to recover the high original energy resolution in case of neutron damage. Finally the status of the new triple crystal detector prototype is given.

The Forward Endcap of the Electromagnetic Calorimeter for the PANDA Detector at FAIR

International Nuclear Information System (INIS)

Albrecht, Malte

2015-01-01

The versatile 4π-detector PANDA will be built at the Facility for Antiproton and Ion Research (FAIR), an accelerator complex, currently under construction near Darmstadt, Germany. A cooled antiproton beam in a momentum range of 1.5 – 15GeV/c will be provided by the High Energy Storage Ring (HESR). All measurements at PANDA rely on an excellent performance of the detector with respect to tracking, particle identification and energy measurement. The electromagnetic calorimeter (EMC) of the PANDA detector will be equipped with 15744 PbWO 4 crystals (PWO-II), which will be operated at a temperature of – 25° C in order to increase the light output. The design of the forward endcap of the EMC has been finalized. The crystals will be read out with Large Area Avalanche Photo Diodes (LAAPDs) in the outer regions and with Vacuum Photo Tetrodes (VPTTs) in the innermost part. Production of photosensor units utilizing charge integrating preamplifiers has begun. A prototype comprised of 216 PbWO4 crystals has been built and tested at various accelerators (CERN SPS, ELSA/Bonn, MAMI/Mainz), where the crystals have been exposed to electron and photon beams of 25MeV up to 15GeV. The results of these test measurements regarding the energy and position resolution are presented

Prototyping the PANDA Barrel DIRC

Energy Technology Data Exchange (ETDEWEB)

Schwarz, C., E-mail: C.Schwarz@gsi.de [GSI Helmholtzzentrum für Schwerionenforschung GmbH, Darmstadt (Germany); Kalicy, G.; Dzhygadlo, R.; Gerhardt, A.; Götzen, K.; Hohler, R.; Kumawat, H.; Lehmann, D.; Lewandowski, B.; Patsyuk, M.; Peters, K.; Schepers, G.; Schmitt, L.; Schwiening, J.; Traxler, M.; Zühlsdorf, M. [GSI Helmholtzzentrum für Schwerionenforschung GmbH, Darmstadt (Germany); Dodokhov, V.Kh. [Joint Institute for Nuclear Research, Dubna (Russian Federation); Britting, A.; Eyrich, W.; Lehmann, A. [Friedrich Alexander-University of Erlangen-Nuremberg, Erlangen (Germany); and others

2014-12-01

The design of the Barrel DIRC detector for the future PANDA experiment at FAIR contains several important improvements compared to the successful BABAR DIRC, such as focusing and fast timing. To test those improvements as well as other design options a prototype was build and successfully tested in 2012 with particle beams at CERN. The prototype comprises a radiator bar, focusing lens, mirror, and a prism shaped expansion volume made of synthetic fused silica. An array of micro-channel plate photomultiplier tubes measures the location and arrival time of the Cherenkov photons with sub-nanosecond resolution. The development of a fast reconstruction algorithm allowed to tune construction details of the detector setup with test beam data and Monte-Carlo simulations.

Front-End Electronics and Feature-Extraction Algorithm for the PANDA Electromagnetic Calorimeter

NARCIS (Netherlands)

Kavatsyuk, M.; Guliyev, E.; Lemmens, P. J. J.; Löhner, H.; Poelman, T. P.; Tambave, G.; Wang, YF; Hu, T

2011-01-01

The PANDA collaboration at FAIR, Germany, will employ antiproton annihilations to investigate yet undiscovered charm-mesons and glueballs aiming to unravel the origin of hadronic masses. A multi-purpose detector for tracking, calorimetry and particle identification is presently being developed to

Post-test sensitivity analysis of OECD/CSNI ISP42 panda experiment by Relap5 code

International Nuclear Information System (INIS)

Zanocco, P.; D'Auria, F.; Galassi, G.M.

2001-01-01

The present document deals with Relap5/Mod3.2 analysis of the International Standard Problem (ISP-42) exercise performed in PANDA facility on April 21-22, 1998. PANDA is installed at PSI (Paul Scherrer Institute). PANDA is a large-scale thermal-hydraulic test facility suitable for the simulation of passive containment for Advanced Light Water Reactors (ALWR). The work focuses phase A of the ISP-42 experiment, including the break in the main steam line, and the Passive Containment Cooling System Start-Up. The objective is to investigate the start-up phenomenology of passive cooling system when steam is injected into cold vessel filled with air and to observe the resulting system behavior. A detailed nodalization was set-up at the University of Pisa, in order to model 3-D flow paths with a 1-D code. The comparison between pre-test predictions and experimental data is discussed. Overall time behavior is reasonably well predicted, showing a rather good and robust overall code behavior in the simulation of the global test scenario. The results of a preliminary post-test analysis are discussed, including the comparison with the experimental data. (authors)

Assessment of multi-dimensional analysis cacpacity of the MARS using the OECD-SETH PANDA tests

International Nuclear Information System (INIS)

Bae, S. W.; Jung, J. J.; Jung, B. D.

2004-01-01

The objectives of OECD/NEA-PANDA tests are to validate and assess computer codes that analyze the non-condensable gas concentrations and mixing phenomena in a reactor containment building. Especially, the main issue is multi-dimensional analysis capability which is involved in the mixing of non-condensable gases, i. e. hydrogen. The main tests consist of a superheated steam flow injection into a large vessel initially filled with air or air/helium mixtures. Then the temperature and concentration of noncondensable gases are measured. A pre-calculation has been performed with the MARS about PANDA Tests even though MARS is not a containment analysis code. Three cases among 25 PANDA Tests are selected and are modeled to simulate the jet plumes and air mixing in a large vessel. The dimensions of large vessel are 4 m diameter and 8 m height. For the conclusion of calculation, the cylindrical vessel which dimensions are 4 m diameter and 8 m height was simplified as rectangular geometry. It is revealed that the MARS code has the capability to distinguish the multi-dimensional distribution of the velocity and the temperature fields

Design studies of the PWO Forward End-cap calorimeter for PANDA

NARCIS (Netherlands)

Moeini, H.; Al-Turany, M.; Babai, M.; Biegun, A.; Bondarenko, O.; Goetzen, K.; Kavatsyuk, M.; Lindemulder, M. F.; Loehner, H.; Melnychuk, D.; Messchendorp, J. G.; Smit, H. A. J.; Spataro, S.; Veenstra, R.

2013-01-01

The PANDA detection system at FAIR, Germany, is designed to study antiproton-proton annihilations, in order to investigate, among others, the realm of charm-meson states and glueballs, which has still much to reveal. The yet unknown properties of this field are to be unraveled through studying QCD

Adjuvant effects of recombinant giant panda (Ailuropoda melanoleuca) IL-18 on the canine distemper disease vaccine in mice

OpenAIRE

YAN, Yue; NIU, Lili; DENG, Jiabo; WANG, Qiang; YU, Jianqiu; ZHANG, Yizheng; WANG, Jianxi; CHEN, Jiao; WEI, Changhe; TAN, Xuemei

2014-01-01

Canine distemper virus (CDV) is a morbillivirus known to cause morbidity and mortality in a broad range of animals. Giant pandas (Ailuropoda melanoleuca), especially captive ones, are susceptible to natural infection with CDV. Interleukin-18 (IL-18) is a powerful adjuvant molecule that can enhance the development of antigen-specific immunity and vaccine efficacy. In this study, a giant panda IL-18 gene eukaryotic expression plasmid (pcAmIL-18) was constructed. Female BALB/c mice were muscular...

Quincuagésimo primer aniversario del Hospital Antituberculoso Santa Clara de Santafé de Bogotá

Directory of Open Access Journals (Sweden)

Gilberto Rueda Pérez

1993-07-01

Full Text Available EI Hospital Santa Clara fue fundado el 16 de julio de 1942, durante la presidencia del Dr. Eduardo Santos, a solicitud de su esposa dona Lorencita Villegas de Santos. EI hospital se construyo en esa época como sanatorio, para la atención, cuidado humano y científico de los pacientes afectados con tuberculosis. Inicialmente el hospital como con 250 camas para adultos y niños. Su nombre "Santa Clara" fue escogido en recuerdo de Clarita, hija única de los benefactores, muerta prematuramente poco tiempo antes.

La integridad mental del personal clínico de un hospital psiquiátrico, asociada a una alta exigencia emocional y a la organización nociva del trabajo

OpenAIRE

Martínez Jaime, María Magdalena; Albores Gallo, Lilia; Márquez Caraveo, María Elena

2012-01-01

El objetivo de esta investigación fue evaluar los riesgos asociados a las formas nocivas de la organización del trabajo, que unidas a ciertas exigencias psicosociales coadyuvan en la génesis del malestar mental, la falta de vitalidad, el estrés y la insatisfacción laboral de los psiquiatras, psicólogos y residentes del Hospital Psiquiátrico Infantil (HPI). Material y métodos El diseño del estudio fue observacional, transversal y descriptivo. Instrumento. El Cuestionario Psicosocial de Copenha...

Technical Design Report for the PANDA Solenoid and Dipole Spectrometer Magnets

CERN Document Server

Erni, W; Krusche, B; Steinacher, M; Heng, Y; Liu, Z; Liu, H; Shen, X; Wang, O; Xu, H; Becker, J; Feldbauer, F; Heinsius, F -H; Held, T; Koch, H; Kopf, B; Pelizaeus, M; Schröder, T; Steinke, M; Wiedner, U; Zhong, J; Bianconi, A; Bragadireanu, M; Pantea, D; Tudorache, A; Tudorache, V; De Napoli, M; Giacoppo, F; Raciti, G; Rapisarda, E; Sfienti, C; Bialkowski, E; Budzanowski, A; Czech, B; Kistryn, M; Kliczewski, S; Kozela, A; Kulessa, P; Pysz, K; Schäfer, W; Siudak, R; Szczurek, A; zycki, W Czy; Domagala, M; Hawryluk, M; Lisowski, E; Lisowski, F; Wojnar, L; Gil, D; Hawranek, P; Kamys, B; Kistryn, St; Korcyl, K; Krzemien, W; Magiera, A; Moskal, P; Rudy, Z; Salabura, P; Smyrski, J; Wronska, A; Al-Turany, M; Augustin, I; Deppe, H; Flemming, H; Gerl, J; Goetzen, K; Hohler, R; Lehmann, D; Lewandowski, B; Lühning, J; Maas, F; Mishra, D; Orth, H; Peters, K; Saitô, T; Schepers, G; Schmidt, C J; Schmitt, L; Schwarz, C; Voss, B; Wieczorek, P; Wilms, A; Brinkmann, K -T; Freiesleben, H; Jaekel, R; Kliemt, R; Wuerschig, T; Zaunick, H -G; Abazov, V M; Alexeev, G; Arefev, A; Astakhov, V I; Barabanov, M Yu; Batyunya, B V; Davydov, Yu I; Dodokhov, V Kh; Efremov, A A; Fedunov, A G; Feshchenko, A A; Galoyan, A S; Grigorian, S; Karmokov, A; Koshurnikov, E K; Kudaev, V Ch; Lobanov, V I; Lobanov, Yu Yu; Makarov, A F; Malinina, L V; Malyshev, V L; Mustafaev, G A; Olshevski, A; Pasyuk, M A; Perevalova, E A; Piskun, A A; Pocheptsov, T A; Pontecorvo, G; Rodionov, V K; Rogov, Yu N; Salmin, R A; Samartsev, A G; Sapozhnikov, M G; Shabratova, A; Shabratova, G S; Skachkova, A N; Skachkov, N B; Strokovsky, E A; Suleimanov, M K; Teshev, R Sh; Tokmenin, V V; Uzhinsky, V V; Vodopyanov, A S; Zaporozhets, S A; Zhuravlev, N I; Zorin, A G; Branford, D; Föhl, K; Glazier, D; Watts, D; Woods, P; Eyrich, W; Lehmann, A; Teufel, A; Dobbs, S; Metreveli, Z; Seth, K; Tann, B; Tomaradze, A G; Bettoni, D; Carassiti, V; Cecchi, A; Dalpiaz, P; Fioravanti, E; Garzia, I; Negrini, M; Savri`e, M; Stancari, G; Dulach, B; Gianotti, P; Guaraldo, C; Lucherini, V; Pace, E; Bersani, A; Macri, M; Marinelli, M; Parodi, R F; Brodski, I; Döring, W; Drexler, P; Düren, M; Gagyi-Palffy, Z; Hayrapetyan, A; Kotulla, M; Kühn, W; Lange, S; Liu, M; Metag, V; Nanova, M; Novotny, R; Salz, C; Schneider, J; Schoenmeier, P; Schubert, R; Spataro, S; Stenzel, H; Strackbein, C; Thiel, M; Thoering, U; Yang, S; Clarkson, T; Cowie, E; Downie, E; Hill, G; Hoek, M; Ireland, D; Kaiser, R; Keri, T; Lehmann, I; Livingston, K; Lumsden, S; MacGregor, D; McKinnon, B; Murray, M; Protopopescu, D; Rosner, G; Seitz, B; Yang, G; Babai, M; Biegun, A K; Bubak, A; Guliyev, E; Jothi, V S; Kavatsyuk, M; Löhner, H; Messchendorp, J; Smit, H; van der Weele, J C; García, F; Riska, D -O; Büscher, M; Dosdall, R; Dzhygadlo, R; Gillitzer, A; Grunwald, D; Jha, V; Kemmerling, G; Kleines, H; Lehrach, A; Maier, R; Mertens, M; Ohm, H; Prasuhn, D; Randriamalala, T; Ritman, J; Roeder, M; Stockmanns, T; Wintz, P; Wüstner, P; Kisiel, J; Li, S; Li, Z; Sun, Z; Xu, H; Fissum, S; Hansen, K; Isaksson, L; Lundin, M; Schröder, B; Achenbach, P; Espi, M C Mora; Pochodzalla, J; Sanchez, S; Sanchez-Lorente, A; Dormenev, V I; Fedorov, A A; Korzhik, M V; Missevitch, O V; Balanutsa, V; Chernetsky, V; Demekhin, A; Dolgolenko, A; Fedorets, P; Gerasimov, A; Goryachev, V; Boukharov, A; Malyshev, O; Marishev, I; Semenov, A; Hoeppner, C; Ketzer, B; Konorov, I; Mann, A; Neubert, S; Paul, S; Weitzel, Q; Khoukaz, A; Rausmann, T; Täschner, A; Wessels, J; Varma, R; Baldin, E; Kotov, K; Peleganchuk, S; Tikhonov, Yu; Boucher, J; Hennino, T; Kunne, R; Ong, S; Pouthas, J; Ramstein, B; Rosier, P; Sudol, M; Van de Wiele, J; Zerguerras, T; Dmowski, K; Korzeniewski, R; Przemyslaw, D; Slowinski, B; Boca, G; Braghieri, A; Costanza, S; Fontana, A; Genova, P; Lavezzi, L; Montagna, P; Rotondi, A; Belikov, N I; Davidenko, A M; Derevshchikov, A A; Goncharenko, Yu M; Grishin, V N; Kachanov, V A; Konstantinov, D A; Kormilitsin, V A; Kravtsov, V I; Matulenko, Yu A; Melnik, Y M; Meshchanin, A P; Minaev, N G; Mochalov, V V; Morozov, D A; Nogach, L V; Nurushev, S B; Ryazantsev, A V; Semenov, P A; Soloviev, L F; Uzunian, A V; Vasilev, A N; Yakutin, A E; Baeck, T; Cederwall, B; Bargholtz, C; Geren, L; Tegnér, P E; Belostotskii, S; Gavrilov, G; Itzotov, A; Kiselev, A; Kravchenko, P; Manaenkov, S; Miklukho, O; Naryshkin, Yu; Veretennikov, D; Vikhrov, V; Zhadanov, A; Fava, L; Panzieri, D; Alberto, D; Amoroso, A; Botta, E; Bressani, T; Bufalino, S; Bussa, M P; Busso, L; De Mori, F; Destefanis, M; Ferrero, L; Grasso, A; Greco, M; Kugathasan, T; Maggiora, M; Marcello, S; Serbanut, G; Sosio, S; Bertini, R; Calvo, D; Coli, S; De Remigis, P; Feliciello, A; Filippi, A; Giraudo, G; Mazza, G; Rivetti, A; Szymanska, K; Tosello, F; Wheadon, R; Morra, O; Agnello, M; Iazzi, F; Szymanska, K; Birsa, R; Bradamante, F; Bressan, A; Martin, A; Clement, H; Ekström, C; Calén, H; Grape, S; Hoeistad, B; Johansson, T; Kupsc, A; Marciniewski, P; Thomé, E; Zlomanczuk, Yu; Díaz, J; Ortiz, A; Borsuk, S; Chlopik, A; Guzik, Z; Kopec, J; Kozlovskii, T; Melnychuk, D; Plominski, M; Szewinski, J; Traczyk, K; Zwieglinski, B; Bühler, P; Gruber, A; Kienle, P; Marton, J; Widmann, E; Zmeskal, J

2009-01-01

This document is the Technical Design Report covering the two large spectrometer magnets of the PANDA detector set-up. It shows the conceptual design of the magnets and their anticipated performance. It precedes the tender and procurement of the magnets and, hence, is subject to possible modifications arising during this process.

The acute phase protein ceruloplasmin as a non-invasive marker of pseudopregnancy, pregnancy, and pregnancy loss in the giant panda.

Directory of Open Access Journals (Sweden)

Erin L Willis

Full Text Available After ovulation, non-pregnant female giant pandas experience pseudopregnancy. During pseudopregnancy, non-pregnant females exhibit physiological and behavioral changes similar to pregnancy. Monitoring hormonal patterns that are usually different in pregnant mammals are not effective at determining pregnancy status in many animals that undergo pseudopregnancy, including the giant panda. Therefore, a physiological test to distinguish between pregnancy and pseudopregnancy in pandas has eluded scientists for decades. We examined other potential markers of pregnancy and found that activity of the acute phase protein ceruloplasmin increases in urine of giant pandas in response to pregnancy. Results indicate that in term pregnancies, levels of active urinary ceruloplasmin were elevated the first week of pregnancy and remain elevated until 20-24 days prior to parturition, while no increase was observed during the luteal phase in known pseudopregnancies. Active ceruloplasmin also increased during ultrasound-confirmed lost pregnancies; however, the pattern was different compared to term pregnancies, particularly during the late luteal phase. In four out of the five additional reproductive cycles included in the current study where females were bred but no birth occurred, active ceruloplasmin in urine increased during the luteal phase. Similar to the known lost pregnancies, the temporal pattern of change in urinary ceruloplasmin during the luteal phase deviated from the term pregnancies suggesting that these cycles may have also been lost pregnancies. Among giant pandas in captivity, it has been presumed that there is a high rate of pregnancy loss and our results are the first to provide evidence supporting this notion.

Nutrient and mineral composition during shoot growth in seven species of Phyllostachys and Pseudosasa bamboo consumed by giant panda.

Science.gov (United States)

Christian, A L; Knott, K K; Vance, C K; Falcone, J F; Bauer, L L; Fahey, G C; Willard, S; Kouba, A J

2015-12-01

During the annual period of bamboo shoot growth in spring, free-ranging giant pandas feed almost exclusively on the shoots while ignoring the leaves and full- height culm. Little is known about the nutritional changes that occur during bamboo shoot growth, if nutritional changes differ among species, or how these changes might influence forage selection. Our objective was to examine the nutrient and mineral composition during three phases of shoot growth (180 cm) for seven species of bamboo (Phyllostachys (P.) aurea, P. aureosulcata, P. bissetii, P. glauca, P. nuda, P. rubromarginata, Pseudosasa japonica) fed to captive giant pandas at the Memphis Zoo. Total dietary fiber content of bamboo shoots increased (p 180 cm, while crude protein, fat and ash exhibited significant declines (p panda diets when available. Journal of Animal Physiology and Animal Nutrition © 2015 Blackwell Verlag GmbH.

Modificación del sistema de extracción y filtración de pelusas para la unidad de lavandería del Hospital Nacional Cayateno Heredia

OpenAIRE

Ramos Garcia, Juan Manuel; Ramos Garcia, Juan Manuel; Ramos Garcia, Juan Manuel

2015-01-01

El presente trabajo, surge como una necesidad de modificar el sistema de extracción y filtración de pelusas, del Área de Secado de la Unidad de Lavandería del Hospital Nacional Cayetano Heredia, por ser una fuente de contaminación ambiental, por el deterioro de sus ductos y la obsolescencia de su sistema de evacuación, que lo hacía directamente al medio ambiente, sin previa filtración. El problema de la contaminación ambiental, está generando el calentamiento del planeta, y como consecuen...

History and use of del Nido cardioplegia solution at Boston Children's Hospital.

Science.gov (United States)

Matte, Gregory S; del Nido, Pedro J

2012-09-01

Cardioplegia is an integral and essential method of myocardial protection for patients of all ages requiring cardiac surgery in which the heart must be stopped. Numerous cardioplegia solutions and delivery methods have been developed. The del Nido cardioplegia solution has been in use for 18 years at Boston Children's Hospital. This is a unique four parts crystalloid to one part whole blood formulation that is generally used in a single-dose fashion. Although the formulation was originally developed for use in pediatric and infant patients, its use for adult cardiac surgery has been expanding. National and international inquiries to our institution regarding this cardioplegia have been increasing over the last 2 years. We present the developmental history, supporting theory, and current protocol for use of what is now referred to as del Nido cardioplegia.

SiPM photosensors and fast timing readout for the Barrel Time-of-Flight detector in bar PANDA

Science.gov (United States)

Suzuki, K.

2018-03-01

The Barrel Time-of-Flight detector system will be installed in the upcoming bar PANDA experiment at FAIR in Germany. The detector has a barrel shape of phi=0.5 m and 1.8 m long, covering about 5 m2, which corresponds to the laboratory polar angle coverage of 22oPANDA Barrel Time-of-Flight detector are presented. The test shows that the current design fulfils satisfactorily the required timing performance (σt~ 56 ps) and the timing performance depends little on the hit position on the surface.

Trauma craneoencefálico severo en la UCIP del Hospital de la Misericordia, 2010-2013

OpenAIRE

Páez Gaitán, Hernán Felipe

2016-01-01

El Trauma Craneoencefálico (TCE) infantil constituye un motivo frecuente de consulta en Urgencias y supone la primera causa de muerte en niños, llegando a ser hasta del 50% en trauma severo. En Colombia se conocen cifras de TCE por algunos estudios descriptivos, pero no existen reportes en Bogotá ni específicamente en TCE severo. Objetivo: Caracterizar el trauma craneoencefálico severo pediátrico en la Unidad de Cuidado intensivo del Hospital de la Misericordia entre los años 2010 y 2013. Ma...

High-quality PWO crystals for the PANDA-EMC

International Nuclear Information System (INIS)

Novotny, R W; Bremer, D; Dormenev, V; Drexler, P; Eissner, T; Kuske, T; Moritz, M

2011-01-01

The paper provides a status report on the crystal production and quality control of a major part of the PbWO 4 crystals for the PANDA-EMC. The results confirm the excellent performance of the new generation of PWO-II. The mechanism of stimulated recovery provides an additional tool to recover radiation damage at room and low temperatures by applying an external infrared light source. Even on-line recovery can be considered if the photo sensor is insensitive in that particular wavelength region.

Diseño de Proyecto de Investigación sobre la prevalencia del Síndrome de Burnout en los profesionales de enfermería del Servicio de Reanimación del Hospital Clínico Universitario de Valladolid

OpenAIRE

Martínez Isabel, Beatriz

2014-01-01

El primer planteamiento para nuestro Trabajo Fin de Grado, fué desarrollar un estudio de investigación con respecto a la prevalencia del estrés laboral y del Síndrome de Burnout en los profesionales de enfermería (enfermeras/TCAEs) del Servicio de Reanimación del Hospital Clínico Universitario de Valladolid (en adelante HCU, pero debido a la falta de autorización por parte de dicho centro para la recogida de datos de los profesionales sanitarios hasta la aprobación y visto b...

The Maternal Maverick/GDF15-like TGF-β Ligand Panda Directs Dorsal-Ventral Axis Formation by Restricting Nodal Expression in the Sea Urchin Embryo

Science.gov (United States)

Haillot, Emmanuel; Molina, Maria Dolores; Lapraz, François; Lepage, Thierry

2015-01-01

Specification of the dorsal-ventral axis in the highly regulative sea urchin embryo critically relies on the zygotic expression of nodal, but whether maternal factors provide the initial spatial cue to orient this axis is not known. Although redox gradients have been proposed to entrain the dorsal-ventral axis by acting upstream of nodal, manipulating the activity of redox gradients only has modest consequences, suggesting that other factors are responsible for orienting nodal expression and defining the dorsal-ventral axis. Here we uncover the function of Panda, a maternally provided transforming growth factor beta (TGF-β) ligand that requires the activin receptor-like kinases (Alk) Alk3/6 and Alk1/2 receptors to break the radial symmetry of the embryo and orient the dorsal-ventral axis by restricting nodal expression. We found that the double inhibition of the bone morphogenetic protein (BMP) type I receptors Alk3/6 and Alk1/2 causes a phenotype dramatically more severe than the BMP2/4 loss-of-function phenotype, leading to extreme ventralization of the embryo through massive ectopic expression of nodal, suggesting that an unidentified signal acting through BMP type I receptors cooperates with BMP2/4 to restrict nodal expression. We identified this ligand as the product of maternal Panda mRNA. Double inactivation of panda and bmp2/4 led to extreme ventralization, mimicking the phenotype caused by inactivation of the two BMP receptors. Inhibition of maternal panda mRNA translation disrupted the early spatial restriction of nodal, leading to persistent massive ectopic expression of nodal on the dorsal side despite the presence of Lefty. Phylogenetic analysis indicates that Panda is not a prototypical BMP ligand but a member of a subfamily of TGF-β distantly related to Inhibins, Lefty, and TGF-β that includes Maverick from Drosophila and GDF15 from vertebrates. Indeed, overexpression of Panda does not appear to directly or strongly activate phosphoSmad1

The Maternal Maverick/GDF15-like TGF-β Ligand Panda Directs Dorsal-Ventral Axis Formation by Restricting Nodal Expression in the Sea Urchin Embryo.

Science.gov (United States)

Haillot, Emmanuel; Molina, Maria Dolores; Lapraz, François; Lepage, Thierry

2015-01-01

Specification of the dorsal-ventral axis in the highly regulative sea urchin embryo critically relies on the zygotic expression of nodal, but whether maternal factors provide the initial spatial cue to orient this axis is not known. Although redox gradients have been proposed to entrain the dorsal-ventral axis by acting upstream of nodal, manipulating the activity of redox gradients only has modest consequences, suggesting that other factors are responsible for orienting nodal expression and defining the dorsal-ventral axis. Here we uncover the function of Panda, a maternally provided transforming growth factor beta (TGF-β) ligand that requires the activin receptor-like kinases (Alk) Alk3/6 and Alk1/2 receptors to break the radial symmetry of the embryo and orient the dorsal-ventral axis by restricting nodal expression. We found that the double inhibition of the bone morphogenetic protein (BMP) type I receptors Alk3/6 and Alk1/2 causes a phenotype dramatically more severe than the BMP2/4 loss-of-function phenotype, leading to extreme ventralization of the embryo through massive ectopic expression of nodal, suggesting that an unidentified signal acting through BMP type I receptors cooperates with BMP2/4 to restrict nodal expression. We identified this ligand as the product of maternal Panda mRNA. Double inactivation of panda and bmp2/4 led to extreme ventralization, mimicking the phenotype caused by inactivation of the two BMP receptors. Inhibition of maternal panda mRNA translation disrupted the early spatial restriction of nodal, leading to persistent massive ectopic expression of nodal on the dorsal side despite the presence of Lefty. Phylogenetic analysis indicates that Panda is not a prototypical BMP ligand but a member of a subfamily of TGF-β distantly related to Inhibins, Lefty, and TGF-β that includes Maverick from Drosophila and GDF15 from vertebrates. Indeed, overexpression of Panda does not appear to directly or strongly activate phosphoSmad1

ESTUDIO COMPARATIVO DEL EFECTO DE CRANEO-ACUPUNTURA VS ACUPUNTURA CORPORAL, EN PACIENTES CON SECUELAS DE ENFERMEDAD VASCULAR CEREBRAL EN EL HOSPITAL REGIONAL DEL INSTITUTO DE SEGURIDAD SOCIAL AL SERVICIO DE LOS TRABAJADORES DEL ESTADO DE PUEBLA

OpenAIRE

MENDEZ MENDEZ, NAZARIO CELSO

2011-01-01

ESTUDIO COMPARATIVO DEL EFECTO DE LA CRANEOACUPUNTURA VS ACUPUNTURA CORPORAL, EN PACIENTES CON SECUELAS DE ENFERMEDAD VASCULAR CEREBRAL EN EL HOSPITAL REGIONAL DEL INSTITUTO DE SEGURIDAD SOCIAL AL SERVICIO DE LOS TRABAJADORES DEL ESTADO DE PUEBLA. LAS SECUELAS DE EVC SON UN PROBLEMA DE SALUD PUBLICA, CON MAYOR FRECUENCIA DE LA ISQUEMIA 81.25 POR CIENTO POR CIENTO Y EN SEGUNDO LUGAR LA HEMORRÁGICA CON EL 18.75 POR CIENTO, EL SEXO FEMENINO ES LA MAS FRECUENTE Y LA EDAD MAS AFECTADA ES DE LO...

The micro vertex detector for the anti PANDA experiment

Energy Technology Data Exchange (ETDEWEB)

Esch, Simone [Forschungszentrum Juelich (Germany); Collaboration: PANDA-Collaboration

2015-07-01

The anti PANDA detector is one of the main experiments at the upcoming Facility for Antiproton and Ion Research (FAIR), which is under construction in Darmstadt, Germany. The fixed-target experiment will explore anti pp annihilations with intense, phase space-cooled beams with momenta between 1.5 and 15 GeV/c. One aim of the detector is to perform high precision measurements of particles like excited charmonium and D mesons. Essential for background suppression is the tagging of D mesons by measuring their decay point. Therefore, a Micro Vertex Detector (MVD) is planned at anti PANDA as the innermost tracking detector. The MVD aims to reconstruct vertices with a resolution better than 100 μm to cope with the decay length of the D{sup ±} mesons (cτ=315 μm) produced with a mean βγ=2. The detector consists of silicon pixel and double-sided silicon strip detectors, arranged in four barrel layers and six disk layers. An overview of the MVD is given in this talk. Recent developments like laboratory and testbeam results of the current pixel front-end ASIC prototype ToPix 4 are shown. The concept of the newly developed strip front-end ASIC PASTA is presented.

A new prototype for the PANDA disc DIRC detector

Energy Technology Data Exchange (ETDEWEB)

Rieke, Julian; Dueren, Michael; Hayrapetyan, Avetik; Foehl, Klaus; Kroeck, Benno; Merle, Oliver; Etzelmueller, Erik; Biguenko, Klim [Justus Liebig Universitaet, Giessen (Germany); Collaboration: PANDA-Collaboration

2014-07-01

The PANDA experiment at the future FAIR facility needs excellent particle identification to do precision studies of antiproton-proton reactions in the 1.5-15 GeV/c momentum range. To fulfill this need, two Cherenkov detectors will be installed in the PANDA target spectrometer, both based on the DIRC concept that uses internally reflected Cherenkov light to perform particle identification, with a focus on the separation of pions and kaons. The Disc-DIRC is designed to cap the forward region of theta angles between 5 and 22 degrees. It will be the first time that a 3D-Disc-DIRC is used for PID in a real physics experiment beyond prototyping. A new prototyping Disc-DIRC apparatus has been constructed at the JLU Giessen. Unlike previous prototypes, this one features a radiator as well as focusing elements made out of fused silica. The Cherenkov light is detected with 22 multi-anode-phototubes and 4 MCP-PMTs, totalling 608 individual pixels. Timing information for each of the latter is generated using the novel TRB3 system developed at GSI. The entire prototype was tested with an electron beam of several GeV/c provided by DESY in Hamburg. The components, their setup and a first analysis of the recorded data will be presented.

Gestión de mantenimiento de la red hospitalaria del estado Anzoátegui, caso: Hospital Universitario "Dr. Luis Razetti"

Directory of Open Access Journals (Sweden)

Tony Castillo Calzadilla

2011-01-01

Full Text Available El objetivo de esta investigación es diagnosticar la gestión de mantenimiento de la red hospitalaria del estado Anzoátegui, a partir de un estudio de caso Hospital "Dr. Luis Razetti", siendo éste el más importante de la región y con ello determinar las causas por las cuales los activos en la red hospitalaria se deterioran tan aceleradamente. El estudio se fundamenta en una investigación "descriptiva" con diseño de campo, recurriéndose a directivos, supervisores y operarios del hospital, quienes respondieron un cuestionario dirigido adaptado de la Norma covenin 2500- 93. Se concluyó que la red hospitalaria del Estado se encuentra en estado grave en cuanto a la Gestión del Mantenimiento para este tipo de instalaciones y que en las mismas se carece de una visión de ingeniería clínica.

cDNA, genomic sequence cloning, and overexpression of EIF1 from the giant panda (Ailuropoda Melanoleuca) and the black bear (Ursus Thibetanus Mupinensis).

Science.gov (United States)

Hou, Wan-ru; Tang, Yun; Hou, Yi-ling; Song, Yan; Zhang, Tian; Wu, Guang-fu

2010-07-01

Eukaryotic initiation factor (eIF) EIF1 is a universally conserved translation factor that is involved in translation initiation site selection. The cDNA and the genomic sequences of EIF1 were cloned successfully from the giant panda (Ailuropoda melanoleuca) and the black bear (Ursus thibetanus mupinensis) using reverse transcription polymerase chain reaction (RT-PCR) technology and touchdown-polymerase chain reaction, respectively. The cDNAs of the EIF1 cloned from the giant panda and the black bear are 418 bp in size, containing an open reading frame (ORF) of 342 bp encoding 113 amino acids. The length of the genomic sequence of the giant panda is 1909 bp, which contains four exons and three introns. The length of the genomic sequence of the black bear is 1897 bp, which also contains four exons and three introns. Sequence alignment indicates a high degree of homology to those of Homo sapiens, Mus musculus, Rattus norvegicus, and Bos Taurus at both amino acid and DNA levels. Topology prediction shows there are one N-glycosylation site, two Casein kinase II phosphorylation sites, and a Amidation site in the EIF1 protein of the giant panda and black bear. In addition, there is a protein kinase C phosphorylation site in EIF1 of the giant panda. The giant panda and the black bear EIF1 genes were overexpressed in E. coli BL21. The results indicated that the both EIF1 fusion proteins with the N-terminally His-tagged form gave rise to the accumulation of two expected 19 kDa polypeptide. The expression products obtained could be used to purify the proteins and study their function further.

First results of the front-end ASIC for the strip detector of the PANDA MVD

Science.gov (United States)

Quagli, T.; Brinkmann, K.-T.; Calvo, D.; Di Pietro, V.; Lai, A.; Riccardi, A.; Ritman, J.; Rivetti, A.; Rolo, M. D.; Stockmanns, T.; Wheadon, R.; Zambanini, A.

2017-03-01

PANDA is a key experiment of the future FAIR facility and the Micro Vertex Detector (MVD) is the innermost part of its tracking system. PASTA (PAnda STrip ASIC) is the readout chip for the strip part of the MVD. The chip is designed to provide high resolution timestamp and charge information with the Time over Threshold (ToT) technique. Its architecture is based on Time to Digital Converters with analog interpolators, with a time bin width of 50 ps. The chip implements Single Event Upset (SEU) protection techniques for its digital parts. A first full-size prototype with 64 channels was produced in a commercial 110 nm CMOS technology and the first characterizations of the prototype were performed.

Magnetic shielding for a transversely polarized target in the longitudinal field of the PANDA solenoid

Energy Technology Data Exchange (ETDEWEB)

Froehlich, Bertold; Ahmed, Samer; Dbeyssi, Alaa; Mora Espi, Maria Carmen; Gerz, Kathrin; Lin, Dexu; Maas, Frank; Martinez, Ana Penuelas; Morales, Cristina; Wang, Yadi [Helmholtz Institut Mainz (Germany); Aguar Bartolome, Patricia [Institut fuer Kernphysik, Johannes Gutenberg-Universitaet Mainz (Germany)

2016-07-01

A transversely polarized target in PANDA would allow for the first time access to the imaginary part of the time like electromagnetic proton form factors, namely the phase angle in the imaginary plane between electric and magnetic form factors. Moreover it would allow for a number of other target single spin asymmetries revealing nucleon structure observables connected with the transverse spin structure of the proton. As a first step for achieving a transverse target polarization, the target region has to be shielded against the 2 T longitudinal magnetic flux from the solenoid of the PANDA spectrometer. We present experimental results on intense magnetic flux shielding using a BSCCO-2212 high temperature superconducting hollow cylinder at liquid helium temperature.

Time resolution below 100 ps for the SciTil detector of PANDA employing SiPM

Science.gov (United States)

Brunner, S. E.; Gruber, L.; Marton, J.; Orth, H.; Suzuki, K.

2014-03-01

The barrel time-of-flight (TOF) detector for the bar PANDA experiment at FAIR in Darmstadt is planned as a scintillator tile hodoscope (SciTil) using 8000 small scintillator tiles. It will provide fast event timing for a software trigger in the otherwise trigger-less data acquisition scheme of bar PANDA, relative timing in a multiple track event topology as well as additional particle identification in the low momentum region. The goal is to achieve a time resolution of σ simeq 100 ps. We have conducted measurements using organic scintillators coupled to Silicon Photomultipliers (SiPM). The results are encouraging such that we are confident to reach the required system time resolution.

Self-Evaluation of PANDA-FBG Based Sensing System for Dynamic Distributed Strain and Temperature Measurement.

Science.gov (United States)

Zhu, Mengshi; Murayama, Hideaki; Wada, Daichi

2017-10-12

A novel method is introduced in this work for effectively evaluating the performance of the PANDA type polarization-maintaining fiber Bragg grating (PANDA-FBG) distributed dynamic strain and temperature sensing system. Conventionally, the errors during the measurement are unknown or evaluated by using other sensors such as strain gauge and thermocouples. This will make the sensing system complicated and decrease the efficiency since more than one kind of sensor is applied for the same measurand. In this study, we used the approximately constant ratio of primary errors in strain and temperature measurement and realized the self-evaluation of the sensing system, which can significantly enhance the applicability, as well as the reliability in strategy making.

Natural Circulation Characteristics at Low-Pressure Conditions through PANDA Experiments and ATHLET Simulations

Directory of Open Access Journals (Sweden)

Domenico Paladino

2008-01-01

Full Text Available Natural circulation characteristics at low pressure/low power have been studied by performing experimental investigations and numerical simulations. The PANDA large-scale facility was used to provide valuable, high quality data on natural circulation characteristics as a function of several parameters and for a wide range of operating conditions. The new experimental data allow for testing and improving the capabilities of the thermal-hydraulic computer codes to be used for treating natural circulation loops in a range with increased attention. This paper presents a synthesis of a part of the results obtained within the EU-Project NACUSP “natural circulation and stability performance of boiling water reactors.” It does so by using the experimental results produced in PANDA and by showing some examples of numerical simulations performed with the thermal-hydraulic code ATHLET.

Technical Design Report for the: PANDA Micro Vertex Detector

CERN Document Server

Erni, W; Krusche, B; Steinacher, M; Heng, Y; Liu, Z; Liu, H; Shen, X; Wang, Q; Xu, H; Albrecht, M; Becker, J; Eickel, K; Feldbauer, F; Fink, M; Friedel, P; Heinsius, F H; Held, T; Koch, H; Kopf, B; Leyhe, M; Motzko, C; Pelizäus, M; Pychy, J; Roth, B; Schröder, T; Schulze, J; Steinke, M; Trifterer, T; Wiedner, U; Zhong, J; Beck, R; Becker, M; Bianco, S; Brinkmann, K -Th; Hammann, C; Hinterberger, F; Jäkel, R; Kaiser, D; Kliemt, R; Koop, K; Schmidt, C; Schnell, R; Thoma, U; Vlasov, P; Wendel, C; Winnebeck, A; Würschig, Th; Zaunick, H -G; Bianconi, A; Bragadireanu, M; Caprini, M; Ciubancan, M; Pantea, D; Tarta, P -D; De Napoli, M; Giacoppo, F; Rapisarda, E; Sfienti, C; Fiutowski, T; Idzik, N; Mindur, B; Przyborowski, D; Swientek, K; Bialkowski, E; Budzanowski, A; Czech, B; Kliczewski, S; Kozela, A; Kulessa, P; Lebiedowicz, P; Malgorzata, K; Pysz, K; Schäfer, W; Siudak, R; Szczurek, A; Brandys, P; Czyzewski, T; Czyzycki, W; Domagala, M; Hawryluk, M; Filo, G; Kwiatkowski, D; Lisowski, E; Lisowski, F; Bardan, W; Gil, D; Kamys, B; Kistryn, St; Korcyl, K; Krzemieñ, W; Magiera, A; Moskal, P; Rudy, Z; Salabura, P; Smyrski, J; Wroñska, A; Al-Turany, M; Arora, R; Augustin, I; Deppe, H; Dutta, D; Flemming, H; Götzen, K; Hohler, G; Karabowicz, R; Lehmann, D; Lewandowski, B; Lühning, J; Maas, F; Orth, H; Peters, K; Saito, T; Schepers, G; Schmidt, C J; Schmitt, L; Schwarz, C; Schwiening, J; Voss, B; Wieczorek, P; Wilms, A; Abazov, V M; Alexeev, G D; Arefiev, V A; Astakhov, V I; Barabanov, M Yu; Batyunya, B V; Davydov, Yu I; Dodokhov, V Kh; Efremov, A A; Fedunov, A G; Feshchenko, A A; Galoyan, A S; Grigoryan, S; Karmokov, A; Koshurnikov, E K; Lobanov, V I; Lobanov, Yu Yu; Makarov, A F; Malinina, L V; Malyshev, V L; Mustafaev, G A; Olshevski, A G; Pasyuk, M A; Perevalova, E A; Piskun, A A; Pocheptsov, T A; Pontecorvo, G; Rodionov, V K; Rogov, Yu N; Salmin, R A; Samartsev, A G; Sapozhnikov, M G; Shabratova, G S; Skachkova, A N; Skachkov, N B; Strokovsky, E A; Suleimanov, M K; Teshev, R Sh; Tokmenin, V V; Uzhinsky, V V; Vodopyanov, A S; Zaporozhets, S A; Zhuravlev, N I; Zorin, A G; Branford, D; Glazier, D; Watts, D; Woods, P; Britting, A; Eyrich, W; Lehmann, A; Uhlig, F; Dobbs, S; Metreveli, Z; Seth, K; Tann, B; Tomaradze, A; Bettoni, D; Carassiti, V; Dalpiaz, P; Drago, A; Fioravanti, E; Garzia, I; Negrini, M; Savriè, M; Stancari, G; Dulach, B; Gianotti, P; Guaraldo, C; Lucherini, V; Pace, E; Bersani, A; Macri, M; Marinelli, M; Parodi, R F; Dormenev, V; Drexler, P; Düren, M; Eisner, T; Foehl, K; Hayrapetyan, A; Koch, P; Krïoch, B; Kühn, W; Lange, S; Liang, Y; Liu, M; Merle, O; Metag, V; Moritz, M; Nanova, M; Novotny, R; Spruck, B; Stenzel, H; Strackbein, C; Thiel, M; Wang, Q; Clarkson, T; Euan, C; Hill, G; Hoek, M; Ireland, D; Kaiser, R; Keri, T; Lehmann, I; Livingston, K; Lumsden, P; MacGregor, D; McKinnon, B; Montgomery, R; Murray, M; Protopopescu, D; Rosner, G; Seitz, B; Yang, G; Babai, M; Biegun, A K; Glazenborg-Kluttig, A; Guliyev, E; Jothi, V S; Kavatsyuk, M; Lemmens, P; Löhner, H; Messchendorp, J; Poelman, T; Smit, H; van der Weele, J C; Sohlbach, H; Büscher, M; Dosdall, R; Dzhygadlo, R; Esch, S; Gillitzer, A; Goldenbaum, F; Grunwald, D; Jha, V; Kemmerling, G; Kleines, H; Lehrach, A; Maier, R; Mertens, M; Ohm, H; Pohl, D L; Prasuhn, D; Randriamalala, T; Ritman, J; Roeder, M; Sterzenbach, G; Stockmanns, T; Wintz, P; Wüstner, P; Xu, H; Kisiel, J; Li, S; Li, Z; Sun, Z; Xu, H; Fissum, K; Hansen, K; Isaksson, L; Lundin, M; Schröder, B; Achenbach, P; Denig, A; Distler, M; Fritsch, M; Kangh, D; Karavdina, A; Lauth, W; Michel, M; Espi, M C Mora; Pochodzalla, J; Sanchez, S; Sanchez-Lorente, A; Sfienti, C; Weber, T; Dormenev, V I; Fedorov, A A; Korzhik, M V; Missevitch, O V; Boukharov, A; Malyshev, O; Marishev, I; Semenov, A; Varma, R; Höppner, C; Ketzer, B; Konorov, I; Mann, A; Neubert, S; Paul, S; Vandenbroucke, M; Zhang, Q; Khoukaz, A; Rausmann, T; Täschner, A; Wessels, J; Baldin, E; Kotov, K; Peleganchuk, S; Tikhonov, Yu; Hennino, T; Imre, M; Kunne, R; Galliard, C Le; Normand, J P Le; Marchand, D; Maroni, A; Ong, S; Pouthas, J; Ramstein, B; Rosier, P; Sudol, M; Theneau, C; Tomasi-Gustafsson, E; Van de Wiele, J; Zerguerras, T; Boca, G; Braghieri, A; Costanza, S; Fontana, A; Genova, P; Lavezzi, L; Montagna, P; Rotondi, A; Buda, V; Abramov, V V; Davidenko, A M; Derevschikov, A A; Goncharenko, Y M; Grishin, V N; Kachanov, V A; Konstantinov, D A; Kormilitsin, V A; Matulenko, Y A; Melnik, Y M; Meschanin, A P; Minaev, N G; Mochalov, V V; Morozov, D A; Nogach, L V; Nurushev, S B; Ryazantsev, A V; Semenov, P A; Soloviev, L F; Uzunian, A V; Vasiliev, A N; Yakutin, A E; Belostotski, S; Gavrilov, G; Itzotov, A; Kisselev, A; Kravchenko, P; Manaenkov, S; Miklukho, O; Naryshkin, Y; Veretennikov, D; Vikhrov, V; Zhadanov, A; Bäck, T; Cederwall, B; Bargholtz, C; Gerén, L; Tegnér, P E; Thørngren, P; von Würtemberg, K M; Fava, L; Alberto, D; Amoroso, A; Bussa, M P; Busso, L; De Mori, F; Destefanis, M; Ferrero, L; Greco, M; Kugathasan, T; Maggiora, M; Marcello, S; Sosio, S; Spataro, S; Calvo, D; Coli, S; De Remigis, P; Filippi, A; Giraudo, G; Lusso, S; Mazza, G; Mignone, M; Rivetti, A; Wheadon, R; Zotti, L; Morra, O; Iazzi, F; Lavagno, A; Quarati, P; Szymanska, K; Birsa, R; Bradamante, F; Bressan, A; Martin, A; Clement, H; Galnander, B; Calén, H; Fransson, K; Johansson, T; Kupsc, A; Marciniewski, P; Thomé, E; Wolke, M; Zlomanczuk, J; Díaz, J; Ortiz, A; Buda, P; Dmowski, K; Korzeniewski, R; Przemyslaw, D; Slowinski, B; Borsuk, S; Chlopik, A; Guzik, Z; Kopec, J; Kozlowski, T; Melnychuk, D; Plominski, M; Szewinski, J; Traczyk, K; Zwieglinski, B; Bühler, P; Gruber, A; Kienle, P; Marton, J; Widmann, E; Zmeskal, J

2012-01-01

This document illustrates the technical layout and the expected performance of the Micro Vertex Detector (MVD) of the PANDA experiment. The MVD will detect charged particles as close as possible to the interaction zone. Design criteria and the optimisation process as well as the technical solutions chosen are discussed and the results of this process are subjected to extensive Monte Carlo physics studies. The route towards realisation of the detector is outlined.

Gastric Dilitation-Volvulus in a Red Panda (Ailurus fulgens)

OpenAIRE

SCHLANSER, Justin R.; AGNEW, Dalen; PAPERD, Deborah W.; HARRISON, Tara M.

2014-01-01

ABSTRACT A 10-year-old male red panda presented acutely with symptoms of shock due to acute abdominal distress and respiratory compromise. Abdominal ultrasound confirmed a severely distended stomach for which passage of an orogastric tube for relief was unsuccessful. Intra-operatively, the stomach was found to be distended and torsed around its long axis supporting the diagnosis of Gastric dilitation-volvulus (GDV). The animal arrested and died intra-operatively and was submitted for necropsy...

Construction of a 7-fold BAC library and cytogenetic mapping of 10 genes in the giant panda (Ailuropoda melanoleuca)

OpenAIRE

Liu, Wei; Zhao, Yonghui; Liu, Zhaoliang; Zhang, Ying; Lian, Zhengxing; Li, Ning

2006-01-01

Abstract Background The giant panda, one of the most primitive carnivores, is an endangered animal. Although it has been the subject of many interesting studies during recent years, little is known about its genome. In order to promote research on this genome, a bacterial artificial chromosome (BAC) library of the giant panda was constructed in this study. Results This BAC library contains 198,844 clones with an average insert size of 108 kb, which represents approximately seven equivalents o...

FACTORES DE RIESGO QUE INCIDEN EN LA RETINOPATÍA DEL PREMATURO EN EL SERVICIO DE NEONATOLOGÍA EN UN HOSPITAL DEL MINISTERIO DE SALUD

OpenAIRE

Guerrero Sausa, Mirella Raquel; Universidad Señor de Sipán; Sánchez Saavedra, Sandra Del Pilar; Universidad Señor de Sipán; Lizárraga De Maguiña, Isabel Graciela; Hospital Regional Docente Las Mercedes

2016-01-01

Este estudio tiene como objetivo: Determinar los Factores de Riesgo que Inciden en la Retinopatía del Prematuro en el Servicio de Neonatología del Hospital Regional Docente las Mercedes - Chiclayo 2014, es de tipo cuantitativo, diseño no experimental, descriptivo y retrospectivo, la población muestral fue de 136 recién nacidos prematuros según criterios de inclusión y exclusión. Las técnicas de recolección de datos son de análisis documental y bibliográfico, teniendo como fuentes primarias la...

Gestión de Procesos Preventivos en Servicios de TI del Hospital México

OpenAIRE

Valverde Piedra, Bryan

2016-01-01

Proyecto final de graduación, Maestría profesional El Hospital México es uno de los hospitales más importantes de Costa Rica, el cual utiliza las Tecnologías de Información (TI) como un gran apoyo para brindar sus servicios diariamente. TI se pueden convertir en el mejor aliado, pero también pueden convertirse en el peor enemigo si no se gestionan de forma adecuada. En el Departamento de TI del hospital siempre se busca mejorar en su operación, por tanto, se observó que han ocurrido inc...

Thermal Stress-Induced Depolarization Loss in Conventional and Panda-Shaped Photonic Crystal Fiber Lasers

Science.gov (United States)

Mousavi, Seyedeh Laleh; Sabaeian, Mohammad

2016-10-01

We report on the modeling of the depolarization loss in the conventional and panda-shaped photonic crystal fiber lasers (PCFLs) due to the self-heating of the fiber, which we call it thermal stress-induced depolarization loss (TSIDL). We first calculated the temperature distribution over the fiber cross sections and then calculated the thermal stresses/strains as a function of heat load per meter. Thermal stress-induced birefringence (TSIB), which is defined as | n x - n y |, in the core and cladding regions was calculated. Finally, TSIDL was calculated for the conventional and panda-shaped PCFLs as a function of fiber length and, respectively, saturated values of 22 and 25 % were obtained which were independent of heat load per meter. For panda-shaped PCFLs, prior to being saturated, an oscillating and damping behavior against the fiber length was seen where in some lengths reached 35 %. The results are close to an experimental value of 30 % reported for a pulsed PCFL (Limpert et al., Opt Express 12:1313-1319, 2004) where the authors reported a degree of polarization of 70 % (i.e., a depolarization of 30 %). The most important result of this work is a saturation behavior of TSIDL at long-enough lengths of the fiber laser which is independent of heat load per meter. To our knowledge, this the first report of TSIBL for PCFLs.

Distinctive diet-tissue isotopic discrimination factors derived from the exclusive bamboo-eating giant panda.

Science.gov (United States)

Han, Han; Wei, Wei; Nie, Yonggang; Zhou, Wenliang; Hu, Yibo; Wu, Qi; Wei, Fuwen

2016-11-01

Stable isotope analysis is very useful in animal ecology, especially in diet reconstruction and trophic studies. Differences in isotope ratios between consumers and their diet, termed discrimination factors, are essential for studies of stable isotope ecology and are species-specific and tissue-specific. Given the specialized bamboo diet and clear foraging behavior, here, we calculated discrimination factors for carbon and nitrogen isotopes from diet to tissues (tooth enamel, hair keratin and bone collagen) for the giant panda (Ailuropoda melanoleuca), a species derived from meat-eating ancestors. Our results showed that carbon discrimination factor obtained from giant panda tooth enamel (ε 13 C diet-enamel = 10.0‰) and nitrogen discrimination factors from hair keratin (Δ 15 N diet-hair = 2.2‰) and bone collagen (Δ 15 N diet-collagen = 2.3‰) were lower, and carbon discrimination factors from hair keratin (Δ 13 C diet-hair = 5.0‰) and bone collagen (Δ 13 C diet-collagen = 6.1‰) were higher than those of other mammalian carnivores, omnivores and herbivores. Such distinctive values are likely the result of a low-nutrient and specialized bamboo diet, carnivore-like digestive system and exceptionally low metabolism in giant pandas. © 2016 International Society of Zoological Sciences, Institute of Zoology/Chinese Academy of Sciences and John Wiley & Sons Australia, Ltd.

Development, design and optimization of a novel endcap DIRC for PANDA

International Nuclear Information System (INIS)

Merle, Oliver

2014-12-01

PANDA, an experiment at the upcoming FAIR facility in Germany, aims at hadron spectroscopy with high precision and rate by exploiting gluon-rich proton-antiproton collisions at momenta from 1.5 GeV/c to 15 GeV/c. Almost 4π coverage by all detector components is a prerequisite to realize this goal. The objective of this thesis is the system design of a novel type of DIRC Cherenkov detector for particle identification at the forward endcap of the PANDA target spectrometer. A key feature of this detector is its compact, planar design which occupies less than 5 cm in beam direction at the acceptance region (θ<22 ) and ∝20 cm at the outer rim where single-photon imaging cameras are located. After the definition of system requirements, the system has been dissected into individual logical components. For each component, possible hardware and design options have been identified, analyzed and evaluated for compliance with the requirements and their impact on the system performance. The optical system and sensor layout have been optimized to compromise complexity and performance, leading to a highly modular detector setup. The resulting definition of the design comprises the specification of the optical setup, the photosensor and the front-end electronics. Further, a concept for the implementation of the pattern reconstruction algorithm for online reconstruction has been proposed. The novel concept also required the development of dedicated particle identification algorithms which permit the efficient analysis of the measured time-correlated photon patterns. These algorithms have been tested with signals generated by means of time-based Monte Carlo simulations which resemble the time characteristics of the quasi-continuous interaction at the highest rate expected at PANDA. The resulting performance estimations predict a π/K-separation up to 4σ at 4 GeV/c.