Johannes Hindi tütar Pille Pae : inimlik headus ei sõltu rezhiimist / Pille Pae ; interv. Anneli Ammas

Index Scriptorium Estoniae

Pae, Pille

2006-01-01

Desintegraatori juhi Johannes Hindi tütar Pille Pae vastab küsimustele, mis puudutavad tema isa armuandmispalve esitamist, isale toetusallkirjade kogumist ning Arnold Rüütli suhteid Johannes Hindiga. Lisa: Kes oli Johannes Hint ja mis Desintegraator?

Dilemmas in diagnostics and therapy of rolandic epilepsy

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Škrijelj Fadil

2011-01-01

Full Text Available Introduction. It is considered that around 20%-30% of patients of all ages and in all continents have wrong epilepsy diagnoses. Diagnostic and consequential therapeutic errors appear, most often, when an adequate diagnostics is not applied. Benign focal epilepsy of childhoods with centrotemporal spikes-rolandic epilepsy, brings very often to diagnostic and therapeutic problems because of persistence of epilepticforms changes in an electroencephalography (EEG recording, several years after establishment of good control over seizures. Case report. We presented 8.5 years-old girl, with the first and the only epileptic seizure at the age of 5, during her sleep. With a clear correlation of EEG record, benign rolandic epilepsy was diagnosed, so the therapy with valproate was introduced. There were no seizures after three years of its implementation. Because of epileptic-forms changes that still persisted in EEG record during her sleep, it was suggested to further use valproate. However, after reconsidering all circumstances it was concluded that the AED should bee slowly reduced up to its exclusion. After a complete stoppage of the therapy, the patient did not have any epileptic seizure for nine months, although EEG still remained pathologically changed during her sleep. Conclusion. A changed EEG record in a patient with rolandic epilepsy must not be a predictor of continuation of antiepileptic drugs therapy, after 2-3 years of successful seizures remission.

Wavelet entropy of BOLD time series: An application to Rolandic epilepsy.

Science.gov (United States)

Gupta, Lalit; Jansen, Jacobus F A; Hofman, Paul A M; Besseling, René M H; de Louw, Anton J A; Aldenkamp, Albert P; Backes, Walter H

2017-12-01

To assess the wavelet entropy for the characterization of intrinsic aberrant temporal irregularities in the time series of resting-state blood-oxygen-level-dependent (BOLD) signal fluctuations. Further, to evaluate the temporal irregularities (disorder/order) on a voxel-by-voxel basis in the brains of children with Rolandic epilepsy. The BOLD time series was decomposed using the discrete wavelet transform and the wavelet entropy was calculated. Using a model time series consisting of multiple harmonics and nonstationary components, the wavelet entropy was compared with Shannon and spectral (Fourier-based) entropy. As an application, the wavelet entropy in 22 children with Rolandic epilepsy was compared to 22 age-matched healthy controls. The images were obtained by performing resting-state functional magnetic resonance imaging (fMRI) using a 3T system, an 8-element receive-only head coil, and an echo planar imaging pulse sequence ( T2*-weighted). The wavelet entropy was also compared to spectral entropy, regional homogeneity, and Shannon entropy. Wavelet entropy was found to identify the nonstationary components of the model time series. In Rolandic epilepsy patients, a significantly elevated wavelet entropy was observed relative to controls for the whole cerebrum (P = 0.03). Spectral entropy (P = 0.41), regional homogeneity (P = 0.52), and Shannon entropy (P = 0.32) did not reveal significant differences. The wavelet entropy measure appeared more sensitive to detect abnormalities in cerebral fluctuations represented by nonstationary effects in the BOLD time series than more conventional measures. This effect was observed in the model time series as well as in Rolandic epilepsy. These observations suggest that the brains of children with Rolandic epilepsy exhibit stronger nonstationary temporal signal fluctuations than controls. 2 Technical Efficacy: Stage 3 J. Magn. Reson. Imaging 2017;46:1728-1737. © 2017 International Society for Magnetic

Removal of endocrine disruptors PAEs in drinking water by gamma-ray irradiation

International Nuclear Information System (INIS)

Zhao Yongfu; Zheng Zheng; Zheng Binguo; Wang Changbao; Li Lili

2012-01-01

Phthalic acid esters (PAEs) belong to environmental endocrine disruptor. The dimethyl phthalate (DMP), diethyl phthalate (DEP) and di-n-butyl phthalate (DBP) were selected for the radiation study. The removal efficiencies of DMP, DEP and DBP in drinking water by gamma-ray irradiation are discussed. The results show that these PAEs could be efficiently removed by gamma-ray irradiation. The removal efficiencies of DMP, DEP and DBP (12 mg/L) in aqueous solutions by 0.8 kGy gamma-ray treatment were 96.6%, 94.5% and 86.2%. The absorbed dose needed for the removal of total carbon in aqueous solutions was much larger than the doses for PAEs degradation. When 2 kGy was selected, the removal efficiencies of TC for DMP, DEP and DBP were only 23.6%, 14.3% and 12.9%. The study results also show that the radiation degradation reaction of PAEs should be divided into two stages: low dose addition reaction and high dose ring-opening reaction. This study is of significance in the disposal of micro-polluted drinking water. (authors)

Memory and phonological awareness in children with Benign Rolandic Epilepsy compared to a matched control group.

Science.gov (United States)

Northcott, Ellen; Connolly, Anne M; Berroya, Anna; McIntyre, Jenny; Christie, Jane; Taylor, Alan; Bleasel, Andrew F; Lawson, John A; Bye, Ann M E

2007-06-01

In a previous study we demonstrated children with Benign Rolandic Epilepsy have normal intelligence and language ability. However, difficulties in verbal and visual memory and aspects of phonological awareness were found compared to normative data. To address the methodological limitations related to the use of normative data, we compared the same cohort of children with Benign Rolandic Epilepsy to a matched control group. Controls (n=40) matched on age and gender to the Benign Rolandic Epilepsy cohort underwent neuropsychological assessment. The life functioning of the control group was assessed using a modified version of the Quality of Life in Childhood Epilepsy Questionnaire (QOLCE). The study confirmed the previous findings of memory and phonological awareness difficulties. In addition, the children with Benign Rolandic Epilepsy had significantly lower IQ scores than the matched control group. Paired sample t-tests showed that on 8 of 11 QOLCE scales, children with Benign Rolandic Epilepsy were rated by parents as having poorer life functioning compared to matched controls, including lower parental ratings on the subscales of memory and language. Benign Rolandic Epilepsy has an excellent seizure prognosis, but this study further emphasizes potential cognitive difficulties. Using an age and gender matched control group, the previous findings of memory and phonological awareness difficulties were validated. These problems in cognition were also identified by parents of children with Benign Rolandic Epilepsy as problematic and impacting upon the child's quality of life.

Storytelling Permutations in the Performance of Life Narrative Betty Roland's Caviar for Breakfast.

Directory of Open Access Journals (Sweden)

Maureen Clark

2013-11-01

Full Text Available Throughout her life, Australian storyteller and playwright Betty Roland (1903-1996 was haunted by the lure of travel. Roland's extensive body of work reflects experiences in Joseph Stalin's Soviet Union in the 1930s, the UK in the 1950s and Greece in the 1960s and charts the evolution of a personal and political philosophy marked by world-wide social upheaval. Caviar for Breakfast (1979 revised 1989, the second volume of Roland's autobiographical trilogy, is the subject of this paper. When taken together, the three books provide a fascinating insight into the values and ideas of the mushrooming modern cultures in which Roland travelled, worked and lived. Caviar for Breakfast retraces Roland's adventures in Joseph Stalin's Soviet Union where she spent fifteen months during 1933-34 with her then lover, Guido Baracchi, a wealthy Marxist scholar. The narrative takes its life from the contents of a diary maintained by Roland during that time and her introductory remarks convey the notion that, what follows, is not a literary enterprise of the imagination. The author insists that Caviar for Breakfast is a first-hand account of past realities and not only does her diary hold the ordering of events together, but is the purveyor of truth. The truth status of the diary as a mode of representation is widely accepted in Western culture. This paper argues, however, that it is impossible for any transcription of a life to enjoy a one-to-one ratio with 'what actually happened' as it is for a ghost to re-enter a world which fully resembles the one it left. It is well within the capacity of any imaginative storyteller to construct a counterfeit, or simulated, sense of reality whether or not s/he works with the diary mode of representation.

PAEs occurrence and sources in road dust and soil in/around parks in May in Tianjin, China.

Science.gov (United States)

Zhao, Jie; Ji, Yaqin; Zhu, Zhenyu; Zhang, Wei; Zhang, Lei; Zhao, Jingbo

2018-01-01

This is the first study reporting the presence of six phthalic acid esters (PAEs) in 45 composite soil and road dust samples collected in the urban zone of Tianjin, China. Three sample types (one soil and two road dust) were collected from the city parks. Soil samples (SI) were obtained from inside the park, road dust samples (RDI) were gathered from inside the park roads and the others (RDA) from roads surrounding parks. The range of concentrations of ∑ 6 PAEs in SI, RDI and RDA were 0.07-0.92μgg -1 , 0.42-6.32μgg -1 and 0.40-7.54μgg -1 , respectively. The highest SI ∑ 6 PAEs concentration (0.92μgg -1 in The People's Park) was 13 times higher than that of the lowest content (0.07μgg -1 in XiLiu Park). Furthermore, the spatial distribution of PAEs in RDI showed higher contents in the Nankai and Hexi districts. PAEs concentrations in different types of roads displayed significant differences (P roads such as arterial road > sub-arterial road > branch road. The results of nonparametric tests on ∑ 6 PAEs revealed significant differences between every two different sample types (P < 0.05). The analysis of the six PAEs types indicated DnBP and DEHP were the primary contaminating compounds in all sample types. The PCA results showed cosmetics and personal care products were important sources of PAEs in SI, and plasticizers were the key sources of PAEs in RDI and RDA. Copyright © 2017 Elsevier Inc. All rights reserved.

PAES: Positron annihilation induced Auger electron spectrometer

OpenAIRE

Hugenschmidt, Christoph

2015-01-01

Positron annihilation induced Auger electron spectroscopy (PAES) is a newly developed application for surface studies with high elemental selectivity and exceptional surface sensitivity. The instrument is operated by the Technische Universität München and is located at NEPOMUC.

Prostatic Artery Embolization (PAE) for Symptomatic Benign Prostatic Hyperplasia (BPH): Part 1, Pathological Background and Clinical Implications

International Nuclear Information System (INIS)

Sun, Fei; Crisóstomo, Verónica; Báez-Díaz, Claudia; Sánchez, Francisco M.

2016-01-01

Pathological features of benign prostatic hyperplasia (BPH) dictate various responses to prostatic artery embolization (PAE). Typically, BPH originates in the transition zone and periurethral region, where should be considered the primary target area in PAE procedures. Given that histological heterogeneity of components in hyperplasia nodules, epithelial or stromal, identifying the more responsive nodules to PAE will have clinical implications. Since some lower urinary tract symptoms (LUTS) in patients with BPH are usually related to bladder outlet obstruction-induced changes in bladder function rather than to outflow obstruction directly, proper selection of candidate patients prior to PAE is of great clinical importance. BPH is a typical chronic progressive condition, suggesting PAE could aim not only to relieve LUTS but also to delay or prevent the clinical progression. Awareness of the pathological background of BPH is essential for interventional radiologists to improve clinical outcomes and develop new treatment strategies in clinical practice of PAE

Prostatic Artery Embolization (PAE) for Symptomatic Benign Prostatic Hyperplasia (BPH): Part 1, Pathological Background and Clinical Implications

Energy Technology Data Exchange (ETDEWEB)

Sun, Fei, E-mail: feisun@ccmijesususon.com; Crisóstomo, Verónica, E-mail: crisosto@ccmijesususon.com; Báez-Díaz, Claudia, E-mail: cbaez@ccmijesususon.com; Sánchez, Francisco M., E-mail: msanchez@ccmijesususon.com [Jesús Usón Minimally Invasive Surgery Centre (Spain)

2016-01-15

Pathological features of benign prostatic hyperplasia (BPH) dictate various responses to prostatic artery embolization (PAE). Typically, BPH originates in the transition zone and periurethral region, where should be considered the primary target area in PAE procedures. Given that histological heterogeneity of components in hyperplasia nodules, epithelial or stromal, identifying the more responsive nodules to PAE will have clinical implications. Since some lower urinary tract symptoms (LUTS) in patients with BPH are usually related to bladder outlet obstruction-induced changes in bladder function rather than to outflow obstruction directly, proper selection of candidate patients prior to PAE is of great clinical importance. BPH is a typical chronic progressive condition, suggesting PAE could aim not only to relieve LUTS but also to delay or prevent the clinical progression. Awareness of the pathological background of BPH is essential for interventional radiologists to improve clinical outcomes and develop new treatment strategies in clinical practice of PAE.

Prostatic Artery Embolization (PAE) for Symptomatic Benign Prostatic Hyperplasia (BPH): Part 1, Pathological Background and Clinical Implications.

Science.gov (United States)

Sun, Fei; Crisóstomo, Verónica; Báez-Díaz, Claudia; Sánchez, Francisco M

2016-01-01

Pathological features of benign prostatic hyperplasia (BPH) dictate various responses to prostatic artery embolization (PAE). Typically, BPH originates in the transition zone and periurethral region, where should be considered the primary target area in PAE procedures. Given that histological heterogeneity of components in hyperplasia nodules, epithelial or stromal, identifying the more responsive nodules to PAE will have clinical implications. Since some lower urinary tract symptoms (LUTS) in patients with BPH are usually related to bladder outlet obstruction-induced changes in bladder function rather than to outflow obstruction directly, proper selection of candidate patients prior to PAE is of great clinical importance. BPH is a typical chronic progressive condition, suggesting PAE could aim not only to relieve LUTS but also to delay or prevent the clinical progression. Awareness of the pathological background of BPH is essential for interventional radiologists to improve clinical outcomes and develop new treatment strategies in clinical practice of PAE.

Academic Performance in Children with Rolandic Epilepsy

Science.gov (United States)

Piccinelli, P.; Borgatti, R.; Aldini, A.; Bindelli, D.; Ferri, M.; Perna, S.; Pitillo, G.; Termine, C.; Zambonin, F.; Balottin, U.

2008-01-01

The aim of this study was to investigate the frequency of reading, writing, and calculation disabilities in children with typical rolandic epilepsy (RE) and healthy control children. We also aimed to define the possible electroclinical markers of specific cognitive dysfunctions in RE. School abilities were evaluated and compared in 20 children…

PAES: Positron annihilation induced Auger electron spectrometer

Directory of Open Access Journals (Sweden)

Christoph Hugenschmidt

2015-08-01

Full Text Available Positron annihilation induced Auger electron spectroscopy (PAES is a newly developed application for surface studies with high elemental selectivity and exceptional surface sensitivity. The instrument is operated by the Technische Universität München and is located at NEPOMUC.

Prostatic Artery Embolization (PAE) for Symptomatic Benign Prostatic Hyperplasia (BPH): Part 2, Insights into the Technical Rationale

Energy Technology Data Exchange (ETDEWEB)

Sun, Fei, E-mail: feisun@ccmijesususon.com; Crisóstomo, Verónica, E-mail: crisosto@ccmijesususon.com; Báez-Díaz, Claudia, E-mail: cbaez@ccmijesususon.com; Sánchez, Francisco M., E-mail: msanchez@ccmijesususon.com [Jesús Usón Minimally Invasive Surgery Centre (Spain)

2016-02-15

Rationale of prostatic artery embolization (PAE) in the treatment of symptomatic benign prostatic hyperplasia is conventionally believed to include two parts: shrinkage of the enlarged prostate gland as a result of PAE-induced ischemic infarction and potential effects to relax the increased prostatic smooth muscle tone by reducing the number and density of α{sub 1}-adrenergic receptor in the prostate stroma. This review describes new insights into the likely mechanisms behind PAE, such as ischemia-induced apoptosis, apoptosis enhanced by blockage of androgens circulation to the embolized prostate, secondary denervation following PAE, and potential effect of nitric oxide pathway immediately after embolization. Studies on therapeutic mechanisms in PAE may shed light on potentially new treatment strategies and development of novel techniques.

Current status and historical variations of phthalate ester (PAE) contamination in the sediments from a large Chinese lake (Lake Chaohu).

Science.gov (United States)

Kang, Lei; Wang, Qing-Mei; He, Qi-Shuang; He, Wei; Liu, Wen-Xiu; Kong, Xiang-Zhen; Yang, Bin; Yang, Chen; Jiang, Yu-Jiao; Xu, Fu-Liu

2016-06-01

The residual levels of phthalate esters (PAEs) in the surface and two core sediments from Lake Chaohu were measured with a gas chromatograph-mass spectrometer (GC-MS). The temporal-spatial distributions, compositions of PAEs, and their effecting factors were investigated. The results indicated that di-n-butyl phthalate (DnBP), diisobutyl phthalate (DIBP), and di(2-ethylhexyl) phthalate (DEHP) were three dominant PAE components in both the surface and core sediments. The residual level of total detected PAEs (∑PAEs) in the surface sediments (2.146 ± 2.255 μg/g dw) was lower than that in the western core sediments (10.615 ± 9.733 μg/g) and in the eastern core sediments (5.109 ± 4.741 μg/g). The average content of ∑PAEs in the surface sediments from the inflow rivers (4.128 ± 1.738 μg/g dw) was an order of magnitude higher than those from the lake (0.323 ± 0.093 μg/g dw), and there were similar PAE compositions between the lake and inflow rivers. This finding means that there were important effects of PAE input from the inflow rivers on the compositions and distributions of PAEs in the surface sediments. An increasing trend was found for the residual levels of ΣPAEs, DnBP, and DIBP from the bottom to the surface in both the western and eastern core sediments. Increasing PAE usage with the population growth, urbanization, and industrial and agricultural development in Lake Chaohu watershed would result in the increasing production of PAEs and their resulting presence in the sediments. The significant positive relationships were also found between the PAE contents and the percentage of sand particles, as well as TOC contents in the sediment cores.

Occurrence and risk assessment of phthalate esters (PAEs) in agricultural soils of the Sanjiang Plain, northeast China.

Science.gov (United States)

Wang, He; Liang, Hong; Gao, Da-Wen

2017-08-01

This study looks at the pollution status of six priority control phthalate esters (PAEs) under different cultivation of agricultural soils in the Sanjiang Plain, northeast China. Results show the total concentration of PAEs ranged from 162.9 to 946.9 μg kg -1 with an average value of 369.5 μg kg -1 . PAE concentrations in three types of cultivated soils exhibited decreasing order paddy field (532.1 ± 198.1 μg kg -1 ) > vegetable field (308.2 ± 87.5 μg kg -1 ) > bean field (268.2 ± 48.3 μg kg -1 ). Di-(2-ethylhexyl) phthalate (DEHP) and di-n-butyl phthalate (DnBP) were the most abundant PAEs congeners. Compared with previous studies, agricultural soils in the Sanjiang Plain showed relatively low contamination levels. Anthropogenic activities such as cultivation practices and industrial emissions were associated with the distribution pattern of PAEs. Furthermore, human health risks of PAEs were estimated and the non-cancer risk shown negligible but carcinogenic risk of DEHP exceeded the threshold limits value. PAE contaminants originated from cultivation practices and intense anthropogenic activities result in placing the agricultural soils under a potential risk to human health and also to ecosystems in the Sanjiang Plain. Therefore, the contamination status of PAEs in agricultural soil and potential impacts on human health should attract considerable attention.

Johannes Hindi tütar Pille Pae : inimlik headus ei sõltu režiimist / Pille Pae ; interv. Anneli Ammas

Index Scriptorium Estoniae

Pae, Pille

2006-01-01

Desintegraatori juhi Johannes Hindi tütar Pille Pae vastab küsimustele, mis puudutavad tema isa armuandmispalve esitamist, isale toetusallkirjade kogumist, Arnold Rüütli suhteid Johannes Hindiga. Lisa: Kes oli Johannes Hint ja mis Desintegraator?

Effect of Rolandic Spikes on ADHD Impulsive Behavior

Directory of Open Access Journals (Sweden)

J Gordon Millichap

2007-01-01

Full Text Available The association of Rolandic spikes with the neuropsychological profile of children with attention deficit hyperactivity disorder (ADHD was studied in a total of 48 patients at JW Goethe-University, Frankfurt/Main; and Central Institute of Mental Health, Mannheim, Germany.

Recent trends in operator theory and partial differential equations the Roland Duduchava anniversary volume

CERN Document Server

Natroshvili, David; Shargorodsky, Eugene; Wendland, Wolfgang

2017-01-01

This volume is dedicated to the eminent Georgian mathematician Roland Duduchava on the occasion of his 70th birthday. It presents recent results on Toeplitz, Wiener-Hopf, and pseudodifferential operators, boundary value problems, operator theory, approximation theory, and reflects the broad spectrum of Roland Duduchava's research. The book is addressed to a wide audience of pure and applied mathematicians.

Managing missing scores on the Roland Morris Disability Questionnaire

DEFF Research Database (Denmark)

Lauridsen, Henrik Hein

2009-01-01

systematically dropped from each person’s raw scores and the standardized score was proportionally recalculated. This process was repeated until 6 questions had been dropped from each person’s questionnaire. ·         The error (absolute and percentage) introduced by each level of dropped question was calculated......MANAGING MISSING SCORES ON THE ROLAND MORRIS DISABILITY QUESTIONNAIRE  Peter Kenta and Henrik Hein Lauridsenb  aBack Research Centre and bInstitute of Sports Science and Clinical Biomechanics, University of Southern Denmark Background There is no standard method to calculate Roland Morris...... Disability Questionnaire (RMDQ) sum scores when one or more questions have not been answered. However, missing data are common on the RMDQ and the current options are: calculate a sum score regardless of unanswered questions, reject all data containing unanswered questions, or to impute scores. Other...

Reduced structural connectivity between sensorimotor and language areas in rolandic epilepsy.

Directory of Open Access Journals (Sweden)

René M H Besseling

Full Text Available Rolandic epilepsy (RE is a childhood epilepsy with centrotemporal (rolandic spikes, that is increasingly associated with language impairment. In this study, we tested for a white matter (connectivity correlate, employing diffusion weighted MRI and language testing.Twenty-three children with RE and 23 matched controls (age: 8-14 years underwent structural (T1-weighted and diffusion-weighted MRI (b = 1200 s/mm(2, 66 gradient directions at 3T, as well as neuropsychological language testing. Combining tractography and a cortical segmentation derived from the T1-scan, the rolandic tract were reconstructed (pre- and postcentral gyri, and tract fractional anisotropy (FA values were compared between patients and controls. Aberrant tracts were tested for correlations with language performance.Several reductions of tract FA were found in patients compared to controls, mostly in the left hemisphere; the most significant effects involved the left inferior frontal (p = 0.005 and supramarginal (p = 0.004 gyrus. In the patient group, lower tract FA values were correlated with lower language performance, among others for the connection between the left postcentral and inferior frontal gyrus (p = 0.043, R = 0.43.In RE, structural connectivity is reduced for several connections involving the rolandic regions, from which the epileptiform activity originates. Most of these aberrant tracts involve the left (typically language mediating hemisphere, notably the pars opercularis of the inferior frontal gyrus (Broca's area and the supramarginal gyrus (Wernicke's area. For the former, reduced language performance for lower tract FA was found in the patients. These findings provide a first microstructural white matter correlate for language impairment in RE.

Beyond Barriers: Involving Hispanic Families in the Education Process. Padres a la escuela (PAE).

Science.gov (United States)

Lewis, Magdalena C.

The Padres a la escuela (PAE) or Parents in the School program in San Antonio (Texas) encouraged the participation of Hispanic parents in the education of their children. The successes of the PAE program are used in this guidebook to help parents, program staff, and policy makers in similar efforts. This handbook describes the history,…

Spatio-temporal distributions and the ecological and health risks of phthalate esters (PAEs) in the surface water of a large, shallow Chinese lake

Energy Technology Data Exchange (ETDEWEB)

He, Wei; Qin, Ning; Kong, Xiangzhen; Liu, Wenxiu; He, Qishuang; Ouyang, Huiling; Yang, Chen; Jiang, Yujiao; Wang, Qingmei; Yang, Bin; Xu, Fuliu, E-mail: xufl@urban.pku.edu.cn

2013-09-01

The spatio-temporal distributions and the ecological and health risks of PAEs in surface water of Lake Chaohu, the fifth largest lake in China, were studied based on the monthly monitoring of six PAE congeners from May 2010 to April 2011. The annual total concentration of the six PAE congeners (Σ{sub 6}PAE) in the surface water ranged from 0.467 to 17.953 μg L{sup −1}, with the average value of 4.042 ± 3.929 μg L{sup −1}. The di-n-butyl phthalate (DnBP) that dominated the Σ{sub 6}PAE at 65.8% was found at its highest and lowest levels in the western lake (TX) and eastern drinking water source area (JC), respectively. The temporal distributions of Σ{sub 6}PAE showed that the highest and lowest levels were observed in September 2010 and June 2010, respectively. The different relationships between the runoff and the PAEs with low and high levels of carbon might suggest their different sources. The DnBP had much greater ecological risks than the other studied PAE congeners as indicated by its potential affected fractions (PAFs) and the margin of safety (MOS10). The PAE congeners studied posed little health risk to the nearby male and female citizens. - Highlights: • Monthly variation in PAEs was first investigated in a large Chinese shallow lake. • Ecological and health risks with uncertainty were determined. • PAEs with low and high level of carbon would be from different sources. • DnBP predominated within PAE congeners and posed a much greater ecological risks. • The studied PAE congeners posed little health risks to the nearby citizens.

Upgrade of the Surface Spectrometer at NEPOMUC for PAES, XPS and STM Investigations

Science.gov (United States)

Zimnik, S.; Lippert, F.; Hugenschmidt, C.

2014-04-01

The characterization of the elemental composition of surfaces is of great importance for the understanding of many surface processes, such as surface segregation or oxidation. Positron-annihilation-induced Auger Electron Spectroscopy (PAES) is a powerful technique for gathering information about the elemental composition of only the topmost atomic layer of a sample. The upgraded surface spectrometer at NEPOMUC (NEtron induced POsitron source MUniCh) enables a comprehensive surface analysis with the complementary techniques STM, XPS and PAES. A new X-ray source for X-ray induced photoelectron spectroscopy (XPS) was installed to gather additional information on oxidation states. A new scanning tunneling microscope (STM) is used as a complementary method to investigate with atomic resolution the surface electron density. The combination of PAES, XPS and STM allows the characterization of both the elemental composition, and the surface topology.

Jan Steen 'de kluchtschilder'

NARCIS (Netherlands)

Vries, Lyckle de

1977-01-01

Diese Arbeit ist den Genrebildern Jan Steens (1629-1679). Der erste Teil enthält eine Auseinandersetzung mit der kunsthistorischen Literatur über Jan Steen. Der dritte Teil enthält einige theoretische Betrachtungen über Jan Steen und siene Stellung in der Geschichte der niederländische Kunst.

Jan Nassalski

CERN Multimedia

2009-01-01

With great sadness we have learned of the sudden and unexpected passing of Jan Nassalski. Jan was a long-standing and faithful friend of CERN, a prominent figure in the deep inelastic scattering community and more recently a diligent CERN Council delegate. But first and foremost he was an ingenuous physicist and dedicated teacher. Jan Nassalski graduated from the Physics Department of Warsaw University in 1966. He started his scientific career at the Warsaw University of Technology and in 1971 joined the Institute of Nuclear Research (now the Soltan Institute for Nuclear Studies), which he finally headed as Scientific Director. He has collaborated with the Laboratory of High Energy Physics in the Joint Institute of Nuclear Studies in Dubna, the Rutherford Laboratory in Didcot, and the Fermi Laboratory in Batavia, but from the late 70’s his activity was concentrated at CERN. His continuous participation in experiments on one of...

The Roland De Witte 1991 Experiment (to the Memory of Roland De Witte

Directory of Open Access Journals (Sweden)

Cahill R. T.

2006-07-01

Full Text Available In 1991 Roland De Witte carried out an experiment in Brussels in which variations in the one-way speed of RF waves through a coaxial cable were recorded over 178 days. The data from this experiment shows that De Witte had detected absolute motion of the earth through space, as had six earlier experiments, beginning with the Michelson- Morley experiment of 1887. His results are in excellent agreement with the extensive data from the Miller 1925/26 detection of absolute motion using a gas-mode Michelson interferometer atop Mt. Wilson, California. The De Witte data reveals turbulence in the flow which amounted to the detection of gravitational waves. Similar effects were also seen by Miller, and by Torr and Kolen in their coaxial cable experiment. Here we bring together what is known about the De Witte experiment.

The Roland De Witte 1991 Experiment (to the Memory of Roland De Witte

Directory of Open Access Journals (Sweden)

Cahill R. T.

2006-07-01

Full Text Available In 1991 Roland De Witte carried out an experiment in Brussels in which variations in the one-way speed of RF waves through a coaxial cable were recorded over 178 days. The data from this experiment shows that De Witte had detected absolute motion of the earth through space, as had six earlier experiments, beginning with the Michelson-Morley experiment of 1887. His results are in excellent agreement with the extensive data from the Miller 1925/26 detection of absolute motion using a gas-mode Michelson interferometer atop Mt. Wilson, California. The De Witte data reveals turbulence in the flow which amounted to the detection of gravitational waves. Similar effects were also seen by Miller, and by Torr and Kolen in their coaxial cable experiment. Here we bring together what is known about the De Witte experiment.

Determination of the post-antibiotic effect (PAE) of combinations of ...

African Journals Online (AJOL)

use

2011-12-12

Dec 12, 2011 ... Post-antibiotic effect (PAE) is one of the pharmacodynamic parameters that can be defined as .... The bacterial strains used in this study were reference strain, ... The mixture was then filtered and the process was repeated by.

Hotell Radisson SAS = Radisson SAS Hotel / Inga Raukas

Index Scriptorium Estoniae

Raukas, Inga, 1967-

2001-01-01

Projekteerija Arhitektuuribüroo Künnapu & Padrik. Arhitektid Vilen Künnapu, Ain Padrik, Eero Palm, Tarmo Maiste. Sisekujundajad Christian Lundwall, Jan Öberg. Konstruktsioonid: Teuvo Meriläinen, Jyrki Rautamäki. Projekt ja hotell valmis 2000. 12 ill.: korruste plaanid, sise- ja välisvaated

Delayed convergence between brain network structure and function in rolandic epilepsy

NARCIS (Netherlands)

Besseling, R.M.H.; Jansen, J.F.A.; Overvliet, G.M.; van der Kruijs, S.J.M.; Ebus, S.C.M.; de Louw, A.J.A.; Hofman, P.A.M.; Aldenkamp, A.P.; Backes, W.H.

2014-01-01

INTRODUCTION: Rolandic epilepsy (RE) manifests during a critical phase of brain development, and has been associated with language impairments. Concordant abnormalities in structural and functional connectivity (SC and FC) have been described before. As SC and FC are under mutual influence, the

The Jan Korec Foundation

International Nuclear Information System (INIS)

2007-01-01

In this video-film activities of the the Jan Korec Foundation are presented. The Jan Korec Foundation supports students of technical sciences, sport activities, science and support of book publishing, humanitarian supports, the environment protection as well as support of different social projects.

Contributions by Jans Wesseling, Jan van Schilfgaarde, and Herman Bouwer to effective and responsible water management in agriculture

NARCIS (Netherlands)

Raats, P.A.C.; Feddes, R.A.

2006-01-01

The first three, successive Editors-in-Chief of Agricultural Water Management, Jans Wesseling, Jan van Schilfgaarde, and Herman Bouwer, were of Dutch origin, received their early training immediately after World War II, and started their careers in the early 1950s: Jans in The Netherlands and Jan

Inimesed linnas = People in the city / Kaja Pae

Index Scriptorium Estoniae

Pae, Kaja

2006-01-01

Eesti näitus "Joint Space" Veneetsia 10. arhitektuuribiennaalil. AB Urban Mark: Ülar Mark, Indrek Tiigi, Kaja Pae, Yoko Alender, Raul Kalvo, Tartu Ülikooli Geograafiainstituut: Rein Ahas, Anto Aasa, Siiri Silm, Positium ICT: Margus Tiru, Erki Saluveer. Näitusel oli eksponeeritud kolm mobiilpositsioneerimisega läbi viidud case study (EKA liikmete liikumisuuring, Eestit külastanud turistide uuring, Tallinna regiooni pendelrändajate uuring). Bibliograafia lk. 33

Jan Koopman - 1957-2009

CERN Multimedia

HR Department

We deeply regret to announce the death of Mr Jan KOOPMAN on 31 October 2009. Mr Jan KOOPMAN, born on 28.07.1957, worked in the BE Department and had been employed at CERN since 16.09.1984. The Director-General has sent his family a message of condolence on behalf of the CERN staff. Social Affairs Human Resources Department At the age of 27 Jan was the last member of SPS-ABM group to be recruited in 1984 and, after a lengthy illness, he has now left us prematurely at the age of 52. As an electronics engineer, equally at home with analog and digital electronics or real-time microprocessor programming, Jan managed, thanks to his competence, professionalism, determination and enthusiasm, to develop, install and maintain many high-performance devices to measure beam characteristics. His human qualities, his moral and intellectual integrity, his love of life and his readiness to offer assistance in professional as well as in private life earned him a rapid integration into the team, of which he was a highl...

Factors Predicting a Good Symptomatic Outcome After Prostate Artery Embolisation (PAE).

Science.gov (United States)

Maclean, D; Harris, M; Drake, T; Maher, B; Modi, S; Dyer, J; Somani, B; Hacking, N; Bryant, T

2018-02-26

As prostate artery embolisation (PAE) becomes an established treatment for benign prostatic obstruction, factors predicting good symptomatic outcome remain unclear. Pre-embolisation prostate size as a predictor is controversial with a handful of papers coming to conflicting conclusions. We aimed to investigate if an association existed in our patient cohort between prostate size and clinical benefit, in addition to evaluating percentage volume reduction as a predictor of symptomatic outcome following PAE. Prospective follow-up of 86 PAE patients at a single institution between June 2012 and January 2016 was conducted (mean age 64.9 years, range 54-80 years). Multiple linear regression analysis was performed to assess strength of association between clinical improvement (change in IPSS) and other variables, of any statistical correlation, through Pearson's bivariate analysis. No major procedural complications were identified and clinical success was achieved in 72.1% (n = 62) at 12 months. Initial prostate size and percentage reduction were found to have a significant association with clinical improvement. Multiple linear regression analysis (r 2  = 0.48) demonstrated that percentage volume reduction at 3 months (r = 0.68, p < 0.001) had the strongest correlation with good symptomatic improvement at 12 months after adjusting for confounding factors. Both the initial prostate size and percentage volume reduction at 3 months predict good symptomatic outcome at 12 months. These findings therefore aid patient selection and counselling to achieve optimal outcomes for men undergoing prostate artery embolisation.

REPRESENTASI ANTI DISKRIMINASI PADA FILM KARTUN 3D ZOOTOPIA (KAJIAN SEMIOTIKA ROLAND BARTHES

Directory of Open Access Journals (Sweden)

Ali Muqoddas

2016-12-01

Full Text Available Isu diskriminasi SARA seperti tiada habisnya terjadi di dunia ini, begitu juga di Indonesia. Hal ini mengakibatkan tema-tema tentang SARA menjadi sensitif ketika dibahas atau pun difilmkan. Hal ini mengakibatkan jarang ditemui film yang mengangkat tentang SARA. Lain halnya dengan Walt Disney. Walt Disney baru-baru ini merilis film kartun 3D yang mengangkat tema anti diskriminasi SARA yang berjudul Zootopia. Film ini menjadi menarik karena isu diskriminasi SARA yang diangkat dibalut dengan konsep yang kreatif hingga sensivitas isu SARA tersebut menjadi berkurang. Representasi anti diskriminasi SARA pada film Zootopia ini selanjutnya dikaji dengan metode semiotika Roland Barthes dengan pendekatan deskriptif kualitatif. Berdasarkan dari analisis, dapat disimpulkan bahwa film Zootopia memuat pesan ideologi tentang anti diskriminasi SARA bahwa kedudukan manusia dimata manusia yang lain pada hakikatnya adalah sama. Setiap manusia berhak dan wajib memperlakukan dan diperlakukan secara bijak tanpa memperdulikan background asal manusia itu sendiri. Penghargaan pada setiap individu tidak didasarkan pada faktor keturunan, ras, suku ataupun agama, namun didasarkan pada prestasi dari individu itu sendiri. Kata Kunci: diskriminasi SARA, Zootopia, Roland Barthes Abstract The issue of racial discrimination as an endless happen in this world, so also in Indonesia. This resulted in the themes of SARA be sensitive when discussed or filmed. This resulted in a rare film that raised about SARA. Another case with Walt Disney. Walt Disney recently released 3D animated film that mengangat theme of anti-discrimination SARA entitled Zootopia. This film is interesting because racial discrimination issues raised wrapped with a creative concept to the sensitivity of the racial issues be reduced. SARA anti-discrimination representation on film Zootopia is further studied with Roland Barthes semiotic methods with qualitative descriptive approach. Based on the analysis, it can

The application of welat latino for creating paes in solo wedding bride

Science.gov (United States)

Ihsani, Ade Novi Nurul; Krisnawati, Maria; Prasetyaningtyas, Wulansari; Anggraeni, Puput; Bela, Herlina Tria; Zunaedah, Putri Wahyu

2018-03-01

The purposes of this research were: 1) to find out the process of creating innovative welat, 2) to find out how to use innovative welat for Solo wedding bride paes creation. The method used in the research was research and development (R & D). Sampling technique in this research was purposive sampling by using 13 people as models. The data collection technique used observation and documentation. Data analysis technique used descriptive technique. The results of the study showed that 1) there were two times design change of the validity of welat creation, each product passed through several stages of designing, forming, determining the material and printing, 3) the first way of using the welat determined the distance dot between the cengkorongan of both forms by using welat according to the existed mold. In conclusion, Innovative welat can produce paes in accordance with the standard and shorten the process.

Roland Barthes and Photography Roland Barthes e a fotografia

Directory of Open Access Journals (Sweden)

Rodrigo Fontanari

2010-03-01

Full Text Available This is a review article and a short exegesis from one of the most important texts of international commentators, especially those not yet translated into Portuguese, that we may consider the last work in Barthes’s life, Camara Lucida. What is proposed here is to offer subsidies to elucidate this important work, which, thirty years after its formation, it hasn’t been so much studied, and its huge contribution to science communication got lost, and especially the reflections on the role of photographic image in the contemporary world. It’s possible to make some hypothesis that, being a semioclasta, rather than an iconoclast, Barthes was in a better position to read and understand images. O presente artigo constitui-se numa resenha e numa pequena exegese de alguns dos mais notáveis textos de comentadores internacionais, notadamente aqueles ainda não traduzidos em língua portuguesa, a se consagrar ao derradeiro livro de Roland Barthes publicado em vida do autor: A câmara clara. O que aqui se propõe é oferecer subsídios para uma melhor elucidação dessa importante obra, que, a trinta anos de seu surgimento, continua pouco estudada, sendo assim desperdiçada sua enorme contribuição às ciências da comunicação e, sobretudo, às reflexões em torno do papel da imagem fotográfica no mundo contemporâneo. Sustentamos a hipótese de que, sendo um semioclasta, mais que um iconoclasta, Barthes estava em melhor posição para ler e entender imagens.

Deletions in 16p13 including GRIN2A in patients with intellectual disability, various dysmorphic features, and seizure disorders of the rolandic region.

NARCIS (Netherlands)

Reutlinger, C.; Helbig, I.; Gawelczyk, B.; Subero, J.I.; Tonnies, H.; Muhle, H.; Finsterwalder, K.; Vermeer, S.; Pfundt, R.; Sperner, J.; Stefanova, I.; Gillessen-Kaesbach, G.; Spiczak, S. von; Baalen, A. van; Boor, R.; Siebert, R.; Stephani, U.; Caliebe, A.

2010-01-01

Seizure disorders of the rolandic region comprise a spectrum of different epilepsy syndromes ranging from benign rolandic epilepsy to more severe seizure disorders including atypical benign partial epilepsy/pseudo-Lennox syndrome,electrical status epilepticus during sleep, and Landau-Kleffner

Prostatic Tissue Elimination After Prostatic Artery Embolization (PAE): A Report of Three Cases

Energy Technology Data Exchange (ETDEWEB)

Leite, Leandro Cardarelli; Assis, Andre Moreira de; Moreira, Airton Mota [University of Sao Paulo, Department of Radiology (Brazil); Harward, Sardis Honoria [The Dartmouth Institute for Health Policy and Clinical Practice (United States); Antunes, Alberto Azoubel [University of Sao Paulo, Discipline of Urology (Brazil); Carnevale, Francisco Cesar, E-mail: francisco.carnevale@criep.com.br [University of Sao Paulo, Department of Radiology (Brazil)

2017-06-15

PurposeWe report three cases of spontaneous prostatic tissue elimination through the urethra while voiding following technically successful prostatic artery embolization (PAE) as a treatment for lower urinary tract symptoms (LUTS) related to benign prostatic hyperplasia (BPH).MethodsAll patients were embolized with 100- to 300-μm microspheres alone or in combination with 300- to 500-μm microspheres.ResultsDuring follow-up prior to eliminating the tissue fragments, the three patients all presented with intermittent periods of LUTS improvement and aggravation. After expelling the prostatic tissue between 1 and 5 months of follow-up, significant improvements in LUTS and urodynamic parameters were observed in all patients.ConclusionsUrethral obstruction after PAE caused by sloughing prostate tissue is a potential complication of the procedure and should be considered in patients with recurrent LUTS in order to avoid inappropriate management.

Managing missing scores on the Roland Morris Disability Questionnaire

DEFF Research Database (Denmark)

Kent, Peter; Lauridsen, Henrik Hein

2011-01-01

Study Design: Analysis of Roland Morris Disability Questionnaire (RMDQ) and Oswestry Disability Index (Oswestry) responses.Objectives: To determine the prevalence of unanswered questions on the RMDQ23 (23-item RMDQ version) and Oswestry questionnaires. To determine if managing RMDQ23 missing data...... fully completed RMDQ23 and matching Oswestry questionnaire sets. Raw sum scores were calculated, and questions systematically dropped. At each stage, sum scores were converted to a score on a 0-100 scale and the error calculated. Wilcoxon Tests were used to compare the magnitude of the error scores...

In Memoriam: Professor Jan M. Hoem

Directory of Open Access Journals (Sweden)

James W. Vaupel

2017-02-01

Full Text Available Jan Hoem died on Saturday in Stockholm after a long illness. Jan became Director of the Max Planck Institute for Demographic Research (MPIDR in 1999; he and I jointly led the Institute for almost eight years. During this period he served as Editor of Demographic Research; he took on this responsibility shortly after the journal was launched and built the journal into a respected online source of cutting-edge analysis. Jan was a superb colleague, with very good judgment, a delightful sense of humor, and deep devotion to research quality. A pioneer of event history analysis, he understood the subtleties of the subject better than anyone else. Jan was born and educated in Norway and worked in Oslo before becoming Professor in Copenhagen and then Professor in Stockholm, where he established SUDA, a leading demographic research initiative. His dedication to high-quality, statistically sophisticated population research at SUDA and MPIDR as well as in the journal Demographic Research substantially advanced the discipline of demography. Jan was a warm and generous teacher, a loyal colleague, and a caring friend whom many people will long remember with gratitude and respect. James W. Vaupel Publisher, Demographic Research

Association of PAEs with Precocious Puberty in Children: A Systematic Review and Meta-Analysis

Directory of Open Access Journals (Sweden)

Yi Wen

2015-12-01

Full Text Available Background: Precocious puberty (PP currently affects 1 in 5000 children and is 10 times more common in girls. Existing studies have tried to detect an association between phathalic acid esters (PAEs and PP, but the results did not reach a consensus. Objective: To estimate the association between PAEs and children with PP based on current evidence. Methods: Databases including PubMed (1978 to March 2015, OVID (1946 to March 2015, Web of Science (1970 to March 2015, EBSCO (1976 to March 2015, CNKI (1979 to March 2015, WANFANG DATA (1987 to March 2015, CBM (1978 to March 2015 and CQVIP (1989 to March 2015 were searched to identify all case-control studies that determined the exposure and concentration of PAEs and their metabolites in children with PP. Meta-analysis of the pooled standard mean difference (SMD and odds ratio (OR with 95% confidence intervals (CI were calculated. Results: A total of 14 studies involving 2223 subjects were finally included. The pooled estimates showed that PP was associated with di-(2-ethylhexyl-phthalate (DEHP exposure (OR: 3.90, 95% CI: 2.77 to 5.49. Besides, the concentration of DEHP (SMD: 1.73, 95% CI: 0.54 to 2.91 and di-n-butyl phthalate (DBP (SMD: 4.31, 95% CI: 2.67 to 5.95 in the PP group were significantly higher than those in the control group, respectively, while no difference was detected between case and control groups in either serum or urinary concentration of mono-(2-ethylhexyl-phthalate (MEHP, monobutyl phthalate (MBP, mono(2-ethyl-5-oxohexyl phthalate(MEOHP, mono-(2-ethyl-5-carboxypentyl phthalate (MECPP, monomethyl phthalate (MMP, monobenzyl phthalate (MBzP or monoethyl phthalate (MEP. Conclusions: Exposure of DEHP and DBP might be associated with PP risk for girls, however, there is no evidence to show an association between the exposure to most PAE metabolites and PP. Given the moderate strength of the results, well-designed cohort studies with large sample size should be performed in future.

Spatial and temporal variation of phthalic acid esters (PAEs) in atmospheric PM10 and PM2.5 and the influence of ambient temperature in Tianjin, China

Science.gov (United States)

Kong, Shaofei; Ji, Yaqin; Liu, Lingling; Chen, Li; Zhao, Xueyan; Wang, Jiajun; Bai, Zhipeng; Sun, Zengrong

2013-08-01

Phthalic acid esters (PAEs) are produced in large amounts throughout the world and are excessively used in various industries, which have posed a serious threat to human health and the environment. An investigation of six major PAEs congeners in atmospheric PM10 and PM2.5 was synchronously conducted at seven sites belonging to different functional zones in spring, summer and winter in Tianjin, China in 2010. Results showed that the average concentrations of DMP, DEP, DBP, BBP, DEHP and DOP in PM10 were 0.88, 0.73, 12.90, 0.15, 98.29 and 0.83 ng m-3, respectively, and in PM2.5, they were 0.54, 0.30, 8.72, 0.08, 75.68 and 0.33 ng m-3, respectively. DEHP and DBP were the predominant species. The industrial site exhibited highest PAEs values as 135.9 ± 202.8 ng m-3. In winter, the detected percentages for DOP were low. The other five PAEs concentrations were higher in winter than those in spring and summer, which may be related to the influence of emission sources, meteorological parameters and the chemical-physical characteristic of themselves. Except for DOP, other PAEs were negatively correlated with ambient temperature and the relationships were the best fitted as exponential forms. Significant positive correlations were found for PAEs in PM2.5 and PM10, indicating common sources. The PM2.5/PM10 ratios (0.53-0.70) for the six PAEs concentrations suggested that they were preferentially concentrated in finer particles. Principal component analysis indicated the emission from cosmetics and personal care products, plasticizers and sewage and industrial wastewater may be important sources for PAEs in atmospheric particulate matter in Tianjin.

Jan ja Ken - vennad disainerid ja sisearhitektid / Jan Joonas Graps, Ken-Kristjan Ruut ; intervjueerinud Tanel Veenre

Index Scriptorium Estoniae

Graps, Jan Joonas, 1972-

2009-01-01

Jan Joonas Grapsi ja Ken-Kristjan Ruuduga nende loomingust ja kujundamispõhimõtetest. 2004. a. asutasid vennad oma sisearhitektuuri ja disainiga tegeleva firma Jan & Ken OÜ. Pälvisid Eesti Sisearhitektide Liidu 2008. aasta parima ühiskondliku interjööri preemia, EXPO 2010 Eesti paviljoni võistlusel 2. koha

Transurethral Resection of the Prostate (TURP) Versus Original and PErFecTED Prostate Artery Embolization (PAE) Due to Benign Prostatic Hyperplasia (BPH): Preliminary Results of a Single Center, Prospective, Urodynamic-Controlled Analysis

Energy Technology Data Exchange (ETDEWEB)

Carnevale, Francisco C., E-mail: fcarnevale@uol.com.br [University of Sao Paulo Medical School, Interventional Radiology Unit (Brazil); Iscaife, Alexandre, E-mail: iscaifeboni@yahoo.com.br; Yoshinaga, Eduardo M., E-mail: dumuracca@ig.com.br [University of Sao Paulo Medical School, Division of Urology (Brazil); Moreira, Airton Mota, E-mail: motamoreira@gmail.com [University of Sao Paulo Medical School, Interventional Radiology Unit (Brazil); Antunes, Alberto A., E-mail: antunesuro@uol.com.br; Srougi, Miguel, E-mail: srougi@uol.com.br [University of Sao Paulo Medical School, Division of Urology (Brazil)

2016-01-15

PurposeTo compare clinical and urodynamic results of transurethral resection of the prostate (TURP) to original and PErFecTED prostate artery embolization (PAE) methods for benign prostatic hyperplasia.MethodsWe prospectively randomized 30 patients to receive TURP or original PAE (oPAE) and compared them to a cohort of patients treated by PErFecTED PAE, with a minimum of 1-year follow-up. Patients were assessed for urodynamic parameters, prostate volume, international prostate symptom score (IPSS), and quality of life (QoL).ResultsAll groups were comparable for all pre-treatment parameters except bladder contractility and peak urine flow rate (Q{sub max}), both of which were significantly better in the TURP group, and IIEF score, which was significantly higher among PErFecTED PAE patients than TURP patients. All groups experienced significant improvement in IPSS, QoL, prostate volume, and Q{sub max}. TURP and PErFecTED PAE both resulted in significantly lower IPSS than oPAE but were not significantly different from one another. TURP resulted in significantly higher Q{sub max} and significantly smaller prostate volume than either original or PErFecTED PAE but required spinal anesthesia and hospitalization. Two patients in the oPAE group with hypocontractile bladders experienced recurrence of symptoms and were treated with TURP. In the TURP group, urinary incontinence occurred in 4/15 patients (26.7 %), rupture of the prostatic capsule in 1/15 (6.7 %), retrograde ejaculation in all patients (100 %), and one patient was readmitted for temporary bladder irrigation due to hematuria.ConclusionsTURP and PAE are both safe and effective treatments. TURP and PErFecTED PAE yield similar symptom improvement, but TURP is associated with both better urodynamic results and more adverse events.

Managing missing scores on the Roland Morris Disability Questionnaire

DEFF Research Database (Denmark)

Lauridsen, Henrik Hein

Background and purpose: It is likely that the most common method for calculating a Roland Morris Disability Index (RMDQ) sum score is to simply ignore any unanswered questions. In contrast, the raw sum score on the Oswestry Disability Index (ODI) is converted to a 0-100 scale, with the advantage...... of unanswered RMDQ questions was measured in a research and a routine care setting. The accuracy of the RMDQ proportional recalculation method was measured using 311 fully completed RMDQ and matching ODI questionnaire sets. Raw sum scores were calculated, and questions systematically dropped. At each stage, sum...

Occurrence and risk assessment of phthalate esters (PAEs) in vegetables and soils of suburban plastic film greenhouses.

Science.gov (United States)

Wang, Jun; Chen, Gangcai; Christie, Peter; Zhang, Manyun; Luo, Yongming; Teng, Ying

2015-08-01

Phthalate esters (PAEs) are suspected of having adverse effects on human health and have been frequently detected in soils and vegetables. The present study investigated their occurrence and composition in plastic film greenhouse soil-vegetable systems and assessed their potential health risks to farmers exposed to these widespread pollutants. Six priority control phthalates, namely dimethyl phthalate (DMP), diethyl phthalate (DEP), di-n-butyl phthalate (DnBP), butyl benzyl phthalate (BBP), di-(2-ethylhexyl) phthalate (DEHP) and di-n-octyl phthalate (DnOP), were determined in 44 plastic film greenhouse vegetables and corresponding soils. Total PAEs ranged from 0.51 to 7.16mgkg(-1) in vegetables and 0.40 to 6.20mgkg(-1) in soils with average concentrations of 2.56 and 2.23mgkg(-1), respectively. DnBP, DEHP and DnOP contributed more than 90% of the total PAEs in both vegetables and soils but the proportions of DnBP and DnOP in vegetables were significantly (p3.00mgkg(-1) but were plastic film greenhouses. Health risks were mainly by exposure through vegetable consumption and soil ingestion. Copyright © 2015 Elsevier B.V. All rights reserved.

Roland Marais: Pièces de Viole, Livre II, 1738. Suites I–IV [recenze CD

Czech Academy of Sciences Publication Activity Database

Kapsa, Václav

2011-01-01

Roč. 19, č. 7 (2011), s. 54-54 ISSN 1210-8081 Institutional research plan: CEZ:AV0Z90580513 Keywords : music http://www.muzikus.cz/klasicka-hudba- jazz -recenze/Roland-Marais-Pices-de-Viole-Livre-II-1738-Suites-IIV~26~cervenec~2011/

2005. aasta arhitektuurivõistlused

Index Scriptorium Estoniae

2005-01-01

Tulemused: Viljandi Metsakalmistu kabel: I - Andres Lember (Male Arhitektid); Tartu Vabaduse sild: I - Stanislav Shulman, Oleg Samohhin (Peterburi, Transmost); Tartu Mõisavahe kvartali hoonestuskava: I .- Ott Kadarik, Villem Tomiste, Mihkel Tüür (Kosmos); Seewaldi ala planeerimine: I - Jüri Martson, Rasmus Reinolt, Ivo-Martin Veelma (Lokomotiiv); Rotermanni kvartali arhitektuurivõistlus: I - Kosmos; aasta betoonehitis 2004: Ülemiste hotell Tallinnas, Martin Aunin; Lasnamäe Jumalaema kirik: I - Oleg Zhemtshugov (AB Z-Projekt), Nikolai Djatko, Jevgeni Kolomenkin; Pärnu vanalinna ja rannapiirkonna tänavakaubanduse inventari ja jäätmejaamade kujundus: I - Peeter Varrak; Kihnu sadamaala planeerimise ja hoonestamise ideevõistlus: I - Siiri Vallner, Kaire Nõmm, Helina Lass, Anna-Liisa Unt (Kavakava); Narva kolledzhi uus hoone: I - Katrin Koov, S. Vallner (Kavakava) ja Indrek Peil (Head Arhitektid); Randvere algkooli hoone: II - Inga Raukas (Arhitektuuriagentuur); Tartu Toomemäe valgustuse ja arhitektuursete väikevormide ideevõistlus: II - K. Koov ja Heidi Urb (Kabvakava) ning Maarja Kask, Ralf Lõoke, Karli Luik (Salto); Metsakalmistu arhitektide kalmeala: I - M. Kask, R. Lõoke; Skoone bastioni ideevõistlus: I - M. Kask, R. Lõoke, K. Luik (Salto); Mahtra talurahvamuuseum: I -Tomomi Hayashi, Hanno Grossschmidt; parim eramu 2004-2005: metallmaja Tabasalus, Muru & Pere; Tallinna loomaaia läänevärav: I - I. Raukas, Monika Löve, Oliver Soomets; parim puitehitis 2005: Naba lasteaed Pirital, arhitektid Vahur Sova, Lauri Saar, sisearhitekt Mari Tosmin; Pae karjääri revitaliseerimine: III - Veronika Valk, Kerli Raamsalu

A C-band 55% PAE high gain two-stage power amplifier based on AlGaN/GaN HEMT

International Nuclear Information System (INIS)

Zheng Jia-Xin; Ma Xiao-Hua; Zhang Hong-He; Zhang Meng; Hao Yue; Lu Yang; Zhao Bo-Chao; Cao Meng-Yi

2015-01-01

A C-band high efficiency and high gain two-stage power amplifier based on AlGaN/GaN high electron mobility transistor (HEMT) is designed and measured in this paper. The input and output impedances for the optimum power-added efficiency (PAE) are determined at the fundamental and 2nd harmonic frequency (f 0 and 2f 0 ). The harmonic manipulation networks are designed both in the driver stage and the power stage which manipulate the second harmonic to a very low level within the operating frequency band. Then the inter-stage matching network and the output power combining network are calculated to achieve a low insertion loss. So the PAE and the power gain is greatly improved. In an operation frequency range of 5.4 GHz–5.8 GHz in CW mode, the amplifier delivers a maximum output power of 18.62 W, with a PAE of 55.15% and an associated power gain of 28.7 dB, which is an outstanding performance. (paper)

Triangulation applied to Jan H. van Bemmel

NARCIS (Netherlands)

Hasman, A.; Bergemann, D.; McCray, A. T.; Talmon, J. L.; Zvárová, J.

2006-01-01

OBJECTIVE: To describe the person of Jan H. van Bemmel from different points of view. METHOD: Triangulation. RESULTS AND CONCLUSIONS: Jan H. van Bemmel successfully contributed to research and education in medical informatics. He inspired a lot of people in The Netherlands and internationally

Prostate Artery Embolization (PAE) in the Management of Refractory Hematuria of Prostatic Origin Secondary to Iatrogenic Urological Trauma: A Safe and Effective Technique.

Science.gov (United States)

Kably, Isaam; Pereira, Keith; Chong, William; Bhatia, Shivank

2016-02-01

Incidence of refractory hematuria of prostatic origin (RHPO) is extremely rare, with an iatrogenic etiology even rarer. When conservative methods fail to control bleeding, more invasive surgical methods are needed. In this article we describe our experience with prostatic artery embolization (PAE) as a minimally invasive alternative treatment option in patients with RHPO secondary to iatrogenic urologic trauma. Three patients presented with RHPO. The etiologies were transurethral resection of prostate surgery, Foley catheter removal with a supratherapeutic international normalized ratio and self-traumatic Foley catheter removal respectively. Stepwise management with conservative and medical methods failed to control bleeding. Under local anesthesia and moderate sedation, bilateral PAE was performed via a right common femoral artery access and using cone beam computed tomography. An embolic mixture containing 300-500 um Embosphere® Microspheres (Biosphere Medical, Rockland, MA) was injected under fluoroscopic guidance until stasis was achieved. PAE using the described technique was a technical and clinical success in all three patients. Hematuria resolved within a period of 24 hours. There were no intra- or periprocedural complications. PAE offers a reasonable option in treatment of RHPO, regardless of the cause and may be attempted prior to surgical techniques or sometimes in conjunction. Being minimally invasive and performed under local anesthesia, PAE is especially useful when excessive bleeding prevents adequate visualization of a bleeding source during cystoscopy and in the elderly age group with several comorbidities. An added advantage is the prostatic parenchymal ischemia leading to significant prostate volume reduction and alleviation of the obstructive symptoms. Copyright © 2016 Elsevier Inc. All rights reserved.

RBFOX1 and RBFOX3 mutations in rolandic epilepsy

DEFF Research Database (Denmark)

Lal, Dennis; Reinthaler, Eva M; Altmüller, Janine

2013-01-01

Partial deletions of the gene encoding the neuronal splicing regulator RBFOX1 have been reported in a range of neurodevelopmental diseases, including idiopathic generalized epilepsy. The RBFOX1 protein and its homologues (RBFOX2 and RBFOX3) regulate alternative splicing of many neuronal transcripts...... involved in the homeostatic control of neuronal excitability. In this study, we explored if structural microdeletions and exonic sequence variations in RBFOX1, RBFOX2, RBFOX3 confer susceptibility to rolandic epilepsy (RE), a common idiopathic focal childhood epilepsy. By high-density SNP array screening...... that exon deletions and truncating mutations of RBFOX1 and RBFOX3 contribute to the genetic variance of partial and generalized idiopathic epilepsy syndromes....

pH-sensitive micelles self-assembled from polymer brush (PAE-g-cholesterol-b-PEG-b-(PAE-g-cholesterol for anticancer drug delivery and controlled release

Directory of Open Access Journals (Sweden)

Huang X

2017-03-01

Full Text Available Xiangxuan Huang,1 Wenbo Liao,1 Gang Zhang,1 Shimin Kang,1 Can Yang Zhang2 1School of Chemical Engineering and Energy Technology, Dongguan University of Technology, Dongguan, People’s Republic of China; 2Department of Pharmaceutical Sciences, College of Pharmacy, Washington State University, Spokane, WA, USA Abstract: A novel amphiphilic pH-sensitive triblock polymer brush (poly(β-amino esters-g-cholesterol-b-poly(ethylene glycol-b-(poly(β-amino esters-g-cholesterol ((PAE-g-Chol-b-PEG-b-(PAE-g-Chol was designed and synthesized successfully through a three-step reaction, and their self-assembled polymeric micelles were used as hydrophobic anticancer drug delivery carriers to realize effectively controlled release. The critical micelle concentrations were 6.8 µg/mL, 12.6 µg/mL, 17.4 µg/mL, and 26.6 µg/mL at pH values of 7.4, 6.5, 6.0, and 5.0, respectively. The trend of critical micelle concentrations indicated that the polymer had high stability that could prolong the circulation time in the body. The hydrodynamic diameter and zeta potential of the polymeric micelles were influenced significantly by the pH values. As pH decreased from 7.4 to 5.0, the particle size and zeta potential increased from 205.4 nm to 285.7 nm and from +12.7 mV to +47.0 mV, respectively. The pKb of the polymer was confirmed to be approximately 6.5 by the acid–base titration method. The results showed that the polymer had sharp pH-sensitivity because of the protonation of the amino groups, resulting in transformation of the PAE segment from hydrophobic to hydrophilic. Doxorubicin-loaded polymeric micelles were prepared with a high loading content (20% and entrapment efficiency (60% using the dialysis method. The in vitro results demonstrated that drug release rate and cumulative release were obviously dependent on pH values. Furthermore, the drug release mechanism was also controlled by the pH values. The polymer had barely any cytotoxicity, whereas the

ANALISIS SEMIOTIKA ROLAND BARTHES TENTANG FENOMENA JILBOOBS

Directory of Open Access Journals (Sweden)

Hamidah Hamidah

2016-10-01

Full Text Available Hijab/jilbab is a cloth to cover all of women’s body except face and two palms. Now, there is one controversial Hijab trend, which is Jilboobs phenomenon. Basically, jilboobs means have deviation meaning from the nature of veil. Jilboobs is a critic to Muslim women who wear hijab, but they still wear tight dress or blouse. It causes their indentation body looked very clear, especially in her chest. Then, the jilboobs phenomenon is a sign in fashion culture which very interference how Muslim teenagers to dress up now. The function of jibab is not to cover women genitals anymore, but it becomes a mode that break out the religion rules. The jilboobs phenomenon is a negative connotation from the real jilbab function. The writers used Semiotics theory from Roland Barthes to discuss this jilboobs phenomenon. It tried to reveal about abusing the real jilbab function as covering Muslim women’s genitals and a religion symbol.

Matemaatika mänguline õppimine hoiab rutiini eemal : Kohtla-Järve Slaavi Põhikool, Tallinna Pae Gümnaasium

Index Scriptorium Estoniae

2015-01-01

Vestlusest Kohtla-Järve Slaavi Põhikooli matemaatikaõpetaja ja keelekümblusvaldkonna õppealajuhataja Jelena Bezvoditskaja ja Tallinna Pae Gümnaasiumi matemaatikaõpetaja ning algklasside keelekümblusprogrammi juhi Roza Skatškovaga

16p11.2 600 kb Duplications confer risk for typical and atypical Rolandic epilepsy

DEFF Research Database (Denmark)

Reinthaler, Eva M; Lal, Dennis; Lebon, Sebastien

2014-01-01

Rolandic epilepsy (RE) is the most common idiopathic focal childhood epilepsy. Its molecular basis is largely unknown and a complex genetic etiology is assumed in the majority of affected individuals. The present study tested whether six large recurrent copy number variants at 1q21, 15q11.2, 15q1...

Cross-cultural adaptation of the Norwegian versions of the Roland-Morris Disability Questionnaire and the Oswestry Disability Index.

Science.gov (United States)

Grotle, M; Brox, J I; Vøllestad, N K

2003-09-01

To evaluate reliability and construct validity of the Norwegian versions of the Roland Morris Disability Questionnaire and the modified Oswestry Disability Index. Translation of two functional status questionnaires and a cross-sectional study of measurement properties. The questionnaires were translated and back-translated following the Guillemin criteria. The Norwegian versions were tested for 55 patients with acute low back pain and 50 patients with chronic low back pain. Test-retest with a 2-day interval was performed in a subsample of 28 patients from the chronic sample. Reliability was assessed by repeatability according to Bland and Altman, intraclass coefficient and coefficient of variation. Internal consistency was assessed by Cronbach's alpha. Concurrent construct validity was assessed with correlations between the questionnaires and the SF-36, Disability Rating Index and pain intensity. Repeatability of the Roland Morris Disability Questionnaire was 4 points, coefficient of variation 15% and intraclass correlation coefficient 0.89, and of the modified Oswestry Disability Index 11, 12% and 0.88, respectively. Internal consistency was 0.94 for both questionnaires. The questionnaires correlated highly with the physical functioning scale of SF-36, moderately with pain, and low with mental scales of the SF-36. The reliability and construct validity of the Norwegian versions of the Roland Morris Disability Questionnaire and the modified Oswestry Disability Index are acceptable for assessing functional status of Norwegian-speaking patients with low back pain.

EAMJ Jan. Emotional.indd

African Journals Online (AJOL)

2009-01-01

Jan 1, 2009 ... Their specific psychiatric disorders, made using. ICD-10 criteria ... Children infected of HIV are at greater risk for psychological ... poverty, frequent home changes, frequent changes ..... had a life time attempted suicide. Twenty ...

EAMJ Jan. Emotional.indd

African Journals Online (AJOL)

2009-01-01

Jan 1, 2009 ... Volatile inhalants (aviation fuel) ... It can be seen in Table 6 below that the factors ... Factors associated with psychological distress in the HIV sero-positive adolescents ..... diagnosis in adolescents seropositive for the human.

“I Want It All, and I Want It Now”: Lifetime Prevalence and Reasons for Using and Abstaining from Controlled Performance and Appearance Enhancing Substances (PAES among Young Exercisers and Amateur Athletes in Five European Countries

Directory of Open Access Journals (Sweden)

Lambros Lazuras

2017-05-01

Full Text Available Doping use in recreational sports is an emerging issue that has received limited attention so far in the psychological literature. The present study assessed the lifetime prevalence of controlled performance and appearance enhancing substances (PAES, and used behavioral reasoning theory to identify the reasons for using and for avoiding using controlled PAES in young exercisers across five European countries, in the context of the “SAFE YOU” Project. Participants were 915 young amateur athletes and exercisers (M = 21.62; SD = 2.62 from Cyprus, Germany, Greece, Italy, and UK who completed an anonymous questionnaire that included measures of self-reported use of controlled PAES, as well as reasons for using and not using controlled PAES. The results of the descriptive analyses demonstrated that almost one out five exercisers in the sample had a previous experience with controlled PAES. Higher prevalence rates were found in Greece and Cyprus and lower in Italy. The most frequently reported reasons for using controlled PAES included achieving the desired results faster; pushing the self to the (physical limits; and recovering faster after exercise/training. Furthermore, the most frequently reported reasons for not using controlled PAES involved worry about any possible adverse health effects; not feeling the need for using them; and wanting to see what can be achieved naturally without using any controlled PAES. The findings of the present study indicate that the use of controlled PAES is fast becoming a crisis in amateur sports and exercise settings and highlight the need for preventive action and concerted anti-doping education efforts.

Roland Barthes na revista Língua e Literatura (USP

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Laura Taddei Brandini

2015-06-01

Full Text Available This article aims to describe and analyze the reception to the works of Roland Barthes in São Paulo’s academic criticism. To achieve this goal, we study articles published in University of São Paulo’s magazine Língua e Literatura, established in 1972 and still in circulation. The selection of Barthes’ concepts in articles from the magazine highlights the dynamics that governs the perception of the image of the French writer in every Brazilian historical moment: from leader of structuralism, in the 70s, to the post-modern libertarian in the 2000s, we can not only see a difference in the appreciation of his writings, but also a change of the profile of academic critics.

Jan de Witt's Elementa Curvarum Linearum Liber Secundus

CERN Document Server

Grootendorst, Albert W; Bakker, Miente; Erne, Reinie

2010-01-01

Following on from the 2000 edition of Jan De Witt's "Elementa Curvarum Linearum, Liber Primus", this book provides the accompanying translation of the second volume of "Elementa Curvarum Linearum (Foundations of Curved Lines)". One of the first books to be published on Analytic Geometry, it was originally written in Latin by the Dutch statesman and mathematician Jan de Witt, soon after Descartes' invention of the subject. Born in 1625, Jan de Witt served with distinction as Grand Pensionary of Holland for much of his adult life. In mathematics, he is best known for his work

OBITUARY: Professor Jan Evetts in memoriam

Science.gov (United States)

Dew-Hughes, David; Campbell, Archie; Glowacki, Bartek

2005-11-01

It is with great sadness that we report the death of Jan Evetts, who lost his second battle with cancer on 18 August 2005. In 1988 he was appointed Founding Editor of this journal where his leadership created the foundation upon which its success rests today. He made an outstanding series of contributions to the science of superconductivity and to the understanding of superconducting materials, and was an indefatigable champion of the development of applications of superconductivity. The loss to the scientific community is incalculable, as is attested by the many communications received from colleagues throughout the world. Professor Jan Edgar Evetts (1939-2005) Professor Jan Edgar Evetts (1939-2005) Jan was born on 31 March 1939, and attended the Dragon School in Oxford, and later Haileybury. He was awarded an exhibition to read Natural Sciences at Pembroke College, Cambridge in 1958 and took his BA degree in 1961. He then undertook a Certificate of Postgraduate Study in Physics under the supervision of Professor Neville Mott. He was the first student to undertake this newly-instituted course; the title of his thesis was `The Resistance of Transition Metals'. In 1962 he joined David Dew-Hughes' embryonic superconducting materials research group, along with Archie Campbell and Anant Narlikar. In fact it was Jan's enthusiasm for the proposed course of research that helped convince David that he should follow Professor Alan Cottrell's suggestion to apply metallurgical methodology to the study of the factors that controlled critical current density in the type II superconductors that were then under development for applications in magnets. Competing theories for the critical current density at that time were fine filaments or `Mendelssohn Sponge' versus the pinning of Abrikosov quantized vortices. The results of the group's work, to which Jan made a major contribution, came down heavily in favour of the latter theory. Jan's outstanding characteristic was his

EAMJ Jan. Burden.indd

African Journals Online (AJOL)

2009-01-01

Jan 1, 2009 ... developed world where the burden of disease is accurately determined. ... Projections indicate an expected yearly incidence of 15 to 20 million new .... of global mortality and burden of diseases from 2002 to 2030. Plos. Med.

Editorial: A dedication to Professor Jan Evetts

Science.gov (United States)

Weber, Harald; Dew-Hughes, David; Campbell, Archie; Barber, Zoe; Somekh, Rob; Glowacki, Bartek

2006-03-01

A few days before the beginning of the 7th European Conference on Applied Superconductivity we learned that Professor Jan Evetts, a pioneer of superconductor research, a brilliant scientist, a wonderful person and a great personal friend, had passed away. We therefore decided to dedicate the 7th European Conference on Applied Superconductivity to the memory of Jan Evetts. The following citation is based on material provided by his former supervisor (D Dew-Hughes) and his closest co-workers in Cambridge. Professor Jan Edgar Evetts (1939-2005) Professor Jan Edgar Evetts (1939-2005) Jan Evetts passed away after losing his second battle with cancer on 24th August 2005. He made an outstanding series of contributions to the science of superconductivity and to the understanding of superconducting materials and was an indefatigable champion of the development of applications of superconductivity. The loss to the superconductivity community is incalculable, as attested by the many communications received from colleagues throughout the world. Jan was born on 31 March 1939, and attended the Dragon School in Oxford, and later Haileybury. He was awarded an exhibition to read Natural Sciences at Pembroke College, Cambridge. He entered the college in 1958 and took his BA degree in 1961. He then undertook a Certificate of Postgraduate Study in Physics under the supervision of Professor Neville Mott. He was the first student to undertake this newly-instituted course; the title of his thesis was `The Resistance of Transition Metals'. In 1962 he joined David Dew-Hughes' superconducting materials research group, along with Archie Campbell and Anant Narlikar. In fact it was Jan's enthusiasm for the proposed course of research that helped convince David that he should follow Professor Alan Cottrell's suggestion to apply metallurgical methodology to the study of the factors that controlled critical current density in the type II superconductors that were then under development for

EAMJ Jan. Materna.indd

African Journals Online (AJOL)

2009-01-01

Jan 1, 2009 ... and childbirth are exacerbated by poverty, low status of women, lack of ... globally (next to India) in number of maternal deaths. (7). Risk of a woman dying ... reflected in the employment rate of 19% for women, against 87% for ...

Ozone and atmospheric pollution at synoptic scale: the monitoring network Paes

International Nuclear Information System (INIS)

Gheusi, F.; Chevalier, A.; Delmas, R.; Athier, G.; Bouchou, P.; Cousin, J.M.; Meyerfeld, Y.; Laj, P.; Sellegri, K.; Ancellet, G.

2007-01-01

Ozone as an environmental concern extends beyond the questions usually covered by media - stratospheric ozone depletion and urban pollution peaks. Strong expositions to this pollutant are frequent even far from pollution sources, and the background tropospheric content of ozone has been growing fivefold over the last century. In response to this concern at the French national scale, formerly independent monitoring stations have been coordinated since 2004 in a structured network: Paes (French acronym for atmospheric pollution at synoptic scale). The data are put in free access online. (authors)

Respuesta a Escalante (2011 "De cómo el análisis de parsimonia de endemismos (PAE tampoco explica la selección natural" A reply to Escalante (2011 "About how Parsimony Analysis of Endemicity does not explain natural selection either"

Directory of Open Access Journals (Sweden)

Mariano Donato

2012-09-01

Full Text Available Discutimos algunos tópicos que a nuestro entender son controvertidos del trabajo de Escalante (2011. Tanto la definición del PAE como las clasificaciones de los tipos de PAE propuestas por la autora, no reflejan exactamente la propuesta por los autores originales. La defensa que la autora hace a críticas que se han hecho del PAE, creemos que no está justificada. El argumento que utiliza para descalificar estas críticas se contradice con respecto a una de las clasificaciones que propone para el PAE. PAE como método histórico, tiene como objetivo el descubrimiento de relaciones entre áreas. De esta manera, consideramos que el hecho de tener los mismos objetivos que los métodos de la biogeografía cladística es lo que permite su comparación. El PAE considera las especies endémicas de algunas áreas (análogas a sinapomorfías en sistemática filogenética como indicadoras de una historia biótica compartida entre ellas, similar a la aplicación del supuesto 0. La presencia de tales especies en esas áreas también podría explicarse por eventos de dispersión recientes, o bien, porque se encuentran condiciones ecológicas favorables. La pregunta que se le hace al PAE es fundamental para la obtención de hipótesis coherentes, pero no necesariamente la respuesta correcta se obtiene con PAE.We discuss some topics which we believe are controversial on Escalante's work (2011. Both, the definition of PAE and the classification of the types of PAE proposed by the author do not accurately reflect the proposal by the original authors. The defense that the author makes is not justified. The argument used to dismiss these criticisms are inconsistent with the classification proposed for the PAE. PAE as historical method aims at discovering relationships between areas. Thus, we believe that having the same objectives as the methods of cladistic biogeography allow us the comparison. PAE considers the endemic species in shared areas as indicative of

The Jan Breman Omnibus

NARCIS (Netherlands)

Breman, J.

2008-01-01

This Omnibus brings together three classic works of the renowned sociologist and anthropologist, Jan Breman. It comprises Of Peasants, Migrants and Paupers (1985), Wage Hunters and Gatherers (1994), and The Labouring Poor in India (2003), reflecting his scholarship over a period of three decades.

Konksu otsas graafiline disainer Jan Tomson / intervjueerinud Tanel Veenre

Index Scriptorium Estoniae

Tomson, Jan

2009-01-01

Jan Tomson endast, oma loomingust, rulasõidust, muusikategemisest, ajakirjast "Sahtel", igapäevadisainist jm. Jan Tomson on teinud plakateid, plaadikujundusi, logosid, grafitit, disaininud Kumu täpilise bussi ja optilise mustriga trammi ning muud

Het dichtwerk van Jan van Foreest (1585-1651)

NARCIS (Netherlands)

Vries, M. de

2007-01-01

The dissertation consists of an edition of Jan van Foreest's Greek poems and the greater part of those written in Latin, provided with translations and a succinct commentary in Dutch. A number of the Latin poems appears in print for the first time ever. Jan van Foreest (1586-1651) studied arts at

The Human Health Assessment to Phthalate Acid Esters (PAEs and Potential Probability Prediction by Chromophoric Dissolved Organic Matter EEM-FRI Fluorescence in Erlong Lake

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Meichen Ji

2018-05-01

Full Text Available Phthalate acid esters (PAEs are suspected to cause wide environmental pollution and have adverse effects on human health. Three priority control phthalates, namely dimethyl phthalate (DMP, diethyl phthalate (DEP, and dibutyl phthalate (DBP, were determined in 45 water samples from the largest drinking water source in Jilin Province. Chromophoric-dissolved organic matter (CDOM, which are composed of complex compounds and are a proxy for water quality, can be monitored using a fluorometer. This study attempted to understand the correlations of the CDOM fluorescence regional integration (FRI components with PAEs and CDOM characteristics under seasonal and spatial variations in the Erlong Lake. The characteristics of the CDOM absorption parameters in different water samples showed a higher aromatic content and molecular weight in October because of increased terrestrial inputs. The Σ3PAEs concentrations ranged from 0.231 mg L−1 to 0.435 mg L−1 in water, and DEP contributed to more than 90% of the Σ3PAEs. The FRI method identified five fluorescence components: one tyrosine-like (R1, one tryptophan-like (R2, one fulvic-like (R3, one microbial protein-like (R4, and one humic-like (R5 component. However, significant relationships exist between DEP and R3 (R2 = 0.78, p < 0.001, R4 (R2 = 0.77, p < 0.001, and R5 (R2 = 0.58, p < 0.001. Quantifying the relationship between CDOM and PAEs was highly significant, because the results will simplify the componential analysis of pollutants from a spatiotemporal perspective as compared to traditional chemical measurements. The human health risk assessment results revealed no human health risk (HQ < 1 in the Erlong Lake basin.

Aberrant functional connectivity between motor and language networks in rolandic epilepsy.

Science.gov (United States)

Besseling, René M H; Overvliet, Geke M; Jansen, Jacobus F A; van der Kruijs, Sylvie J M; Vles, Johannes S H; Ebus, Saskia C M; Hofman, Paul A M; de Louw, Anton J A; Aldenkamp, Albert P; Backes, Walter H

2013-12-01

Rolandic epilepsy (RE) is an idiopathic focal childhood epilepsy with a well-established neuropsychological profile of language impairment. The aim of this study is to provide a functional correlate that links rolandic (sensorimotor) pathology to language problems using functional MRI. Twenty-three children with RE (8-14 years old) and 21 matched controls underwent extensive language assessment (Clinical Evaluation of Language Fundamentals). fMRI was performed at rest and using word generation, reading, and finger tapping paradigms. Since no activation group differences were found, regions of interest (ROIs) were defined at pooled (patients and controls combined) activation maxima and in contralateral homotopic cortex, and used to assess language lateralization as well as for a resting-state connectivity analysis. Furthermore, the association between connection strength and language performance was investigated. Reduced language performance was found in the children with RE. Bilateral activation was found for both language tasks with some predominance of the left hemisphere in both groups. Compared to controls, patient connectivity was decreased between the left sensorimotor area and right inferior frontal gyrus (planguage scores in the patient group (r=0.49, p=0.02), but not in the controls. Language laterality analysis revealed bilateral language representation in the age range under study (8-14 years). As a consequence, the connection of reduced functional connectivity we found represents an impaired interplay between motor and language networks, and aberrant functional connectivity associated with poorer language performance. These findings provide a first neuronal correlate in terms of aberrant resting-state functional connectivity for language impairment in RE. Copyright © 2013 Elsevier B.V. All rights reserved.

Rain Tolk : "Jan Uuspõld on asendamatu" / Greta Kaupmees

Index Scriptorium Estoniae

Kaupmees, Greta

2006-01-01

Kanal 2 saate "TOP 10" naljameeste pingereas platseerus näitleja Jan Uuspõld 4. kohale. Teda iseloomustades pole üks komöödiafilmi "Jan Uuspõld läheb Tartusse" autoreid Rain Tolk kiitusega kitsi

Biomarkers for the detection of prenatal alcohol exposure (PAE)

DEFF Research Database (Denmark)

Bjerregaard, Lene Berit Skov; Bager, Heidi; Husby, Steffen

2017-01-01

Alcohol exposure during pregnancy can cause adverse effects to the fetus, because it interferes with fetal development, leading to later physical and mental impairment. The most common clinical tool to determine fetal alcohol exposure is maternal self-reporting. However, a more objective and useful...... method is based on the use of biomarkers in biological specimens alone or in combination with maternal self-reporting. This review reports on clinically relevant biomarkers for detection of prenatal alcohol exposure (PAE). A systematic search was performed to ensure a proper overview in existing...... to be applicable for detection of even low levels of alcohol exposure. Meconium is an accessible matrix for determination of FAEEs and EtG, and blood an accessible matrix for determination of PEth....

Elisa Studio showroom = Elisa Studio showroom / Jan Joonas Graps ; kommenteerinud Tiina Kuusisto

Index Scriptorium Estoniae

Graps, Jan Joonas, 1972-

2015-01-01

Elisa Studio showroom Helsingis Lasiplatsi, Mannerheimintie 22-24. Sisekujunduse autorid Jan Joonas Graps, Ken-Kristjan Ruut, Anne Määrmann (JanKen Wisespace). Lühidalt loovstuudiost JanKen Wisespace

EAMJ Jan Hydrotubation.indd

African Journals Online (AJOL)

2009-01-01

Jan 1, 2009 ... oil soluble medium, we used saline solution in our study due to the side effects of oil media and because our intervention was principally for therapeutic reason. Oil media have been associated with persistent contrast medium within the pelvis, allergy or anaphylaxis reaction from intravasation and formation ...

Hats off to CERN's Master of Apprenticeships ! Roland Gay of the HR Department (at right) recently received a special diploma from the Geneva Industrial Union (UIG).

CERN Multimedia

2004-01-01

Presented by Carlo Lamprecht, Head of the Department of Economy, Employment and External Affairs of the State of Geneva, the diploma was awarded in recognition of the 199 CERN apprentices Roland has guided through the Certificat Fédéral de Capacité (CFC), an end-of-apprenticeship certificate awarded by the Cantonal authorities. Roland will be retiring in December 2004 after 37 years of service, 32 of which he spent in the role of apprenticeship supervisor.

Ulgumerelaineid "murdes" / Jan Kaus

Index Scriptorium Estoniae

Kaus, Jan, 1971-

2006-01-01

22. dets. teatris NO99 toimunud ühekordsest aktsioonist "Ulgumerelainetel" S. Mrozheki "Ulgumerel" järgi (lavastaja Tiit Ojasoo). Pärast aktsiooni toimus publiku ja lava vahel arutelu, millest võttis osa Jan Kaus. Teater palus, et ta jätkaks saalis alustatud sõnavõtuga, mida ta kirja teel ka tegi

Heli Laaksonen ja Jan Rahman

Index Scriptorium Estoniae

2006-01-01

Rahman, Jan ; Heli Laaksonen. Maapuupäiv : [luulõtuisi : runoi]. Võru : Võro Selts VKKF : Sammakko, 2000. Kohtumine väljaande tutvustamiseks Tartu Kirjanduse Majas 13. jaan. Vt. ka Eesti Päevaleht : Arkaadia, 13. jaan., lk. 16

Rasch analysis of the 23-item version of the Roland Morris Disability Questionnaire

DEFF Research Database (Denmark)

Kent, Peter; Grotle, Margreth; Dunn, Kate M

2015-01-01

OBJECTIVE: To determine the psychometric properties of the 23-item version of the Roland Morris Disability Questionnaire (RMDQ-23) and to quantify their stability across 2 cultures/languages and 2 types of care-settings. METHODS: Rasch analysis of data from 1,000 patients with low back pain from...... clinical characteristics (such as age, gender, pain intensity, pain duration and care setting), depending on the country. CONCLUSION: As similar results have been found for the RMDQ-24, we believe it is timely to reconsider whether: (i) the RMDQ should be reconstructed using an item-response theory...

EAMJ Jan. Familial 10.indd

African Journals Online (AJOL)

2010-01-01

Jan 1, 2010 ... Its treatment is often costly and associated with high mortality, whereas screening ... occur very early in breast cancer and it should be considered a systemic .... of the disease and confidentiality issues can be expected to have ...

Physique du deuil. Note sur la dernière vie de Roland Barthes

Directory of Open Access Journals (Sweden)

Maïté Snauwaert

2013-03-01

Full Text Available Les remarques sur la tenue de la maison et du corps dans le quotidien domestique, conçue comme une éthique de la fidélité à la mère récemment disparue, apparaissent dans l’écrit privé du Journal de deuil de Roland Barthes comme un écho des observations faites dans le cours sur La préparation du roman. Participant d’une physique du vivre et de l’habiter qui met l’accent sur l’entretien quotidien du lieu, le silence et la difficulté de tout voyage, les « notations » du journal rendent compte de la condensation dans le corps de l’épreuve du deuil, et de la prise de conscience d’un dernier âge de la vie.In the personal writings of Journal de deuil, Roland Barthes’ remarks regarding the maintenance of the home and body are conceived of as an ethic of faithfulness to his recently deceased mother. They are considered in this article as an echo to the observations he makes during his lectures in the course La préparation du roman. Both emphasize the physicality of everyday life and the role played by one’s relationship to the home. By stressing the necessity of silence and the difficulties of leaving “the apartment”, the brief “notations” in the diary translate the physical concentration of the mourning experience, as well as the emergent understanding of a final stage of life.

EAMJ Jan. Internal root 10.indd

African Journals Online (AJOL)

2010-01-01

Jan 1, 2010 ... Before embarking on endodontic therapy, pre- ... Dentistry and Orthodontics, S. W. Maina, BDS, MSc, Senior Lecturer, Department of Conservative and Prosthetic ..... before the tooth is condemned or surgical endodontics.

Rasch scaling of the Oswestry Disability Index and the Roland-Morris Disability Questionnaire

DEFF Research Database (Denmark)

Lauridsen, Henrik Hein; Hartvigsen, Jan

Questionnaire (RMQ) and the Oswestry Disability Index (ODI), however, only few studies have tested these questionnaires using Rasch analysis. This study used Rasch scaling to test the construct validity of the Danish versions of the RMQ (23-item Patrick version) and the ODI (version 2.1a) in a heterogeneous...... on an ordinal scale into interval scaling in addition to optimising the fit of instrument items to the target population. In low back pain research the two most commonly used and well-validated questionnaires to assess functional status in patients with low back pain are the Roland-Morris Disability...

The Roland De Witte Experiment, R. T. Cahill, and the One-Way Speed of Light (Letters to Progress in Physics

Directory of Open Access Journals (Sweden)

Catania J.

2016-01-01

Full Text Available In “The Roland De Witte 1991 Experiment (to the Memory of Roland De Witte” (Progr. Phys , 2006, v. 2(3, 60–65, R.T. Cahill gives us a briefing on his view that interferometer measurements and one-way RF coaxial cable propagation-time measure- ments amount to a detection of the anisotropy in the speed of light. However, while I obtain first order propagation delays in calculations for on e-way transit which would show geometric modulation by Earth’s rotation, I do not agree with Cahill’s simplistic equation that relates the modulation solely to the projection of the absolute velocity vector v on the coaxial cable, called v P by Cahill (ibid., p. 61–62. The reader should be warned that Cahill’s equation for ∆ t (ibid., p.63 is crude compared with a full Special Relativistic derivation.

Prostatic Artery Embolization (PAE) for Benign Prostatic Hyperplasia (BPH) with Haematuria in the Absence of an Upper Urinary Tract Pathology.

Science.gov (United States)

Tapping, Charles R; Macdonald, Andrew; Hadi, Mo; Mortensen, Chloe; Crew, Jeremy; Protheroe, Andrew; Little, Mark W; Boardman, Phil

2018-03-26

To assess the effectiveness of prostate artery embolization (PAE) in the control of haematuria and in patients with benign prostatic hyperplasia (BPH) and normal upper urinary tracts. Twelve consecutive patients with haematuria were included in the prospective study. All patients had prior imaging and cystoscopy to exclude other causes of haematuria. Patients prostate arteries were embolized with particles (200-500 μm), and they were followed up at 3, 12 and 18 months following the procedure. QOL questionnaires, IPSS, IIEF and clinical review were all employed to assess the success of the treatment. To allow useful comparison, patients were age- and prostate volume-matched and compared to patients treated with PAE for BPH without haematuria. All 12/12 cases were technically successful with bilateral PAE being performed. All cases of haematuria resolved by the 3-month follow-up (100%). There was one case of recurrence during the 12-month follow-up (overall clinical success at 18 months 92%). This was due to over anticoagulation and ceased once corrected. There was a reduction in lower urinary tract symptoms noted by improvements in QOL indices, IPSS and IIEF. There was continued success even if the patient was subsequently anticoagulated. There was no associated sexual dysfunction. There was more prostatic arterial branching and volume of embolic required to achieve stasis in BPH and haematuria than in BPH alone (p BPH allows a significant improvement in QOL.

Jan Potocki et le "Gothic Novel"

Science.gov (United States)

Finne, Jacques

1970-01-01

Establishes a parallel between the supernatural and fantastic qualities of Le Comte Jan Potocki's literary works, and the English gothic novels by comparing the elements of terror, mysterious atmosphere, and the supernatural beings involved. (DS)

Vaata, mis Tallinn inimesega teeb! / Madis Jürgen, Jan Uuspõld

Index Scriptorium Estoniae

Jürgen, Madis, 1962-

2007-01-01

Jan Uuspõld, Madis Jürgen ja Rain Tolk vaatavad filmistuudio montaazhitoas Rain Tolgi-Andres Maimiku äsjavalminud komöödiat "Jan Uuspõld läheb Tartusse" ja kommenteerivad. (OÜ "Kuukulgur Film", 2007)

Roland Barthes and the Great Proletarian Revolution China: An Approach to Autobiographical Writing in Diary of My Trip to China

Directory of Open Access Journals (Sweden)

Cecilia Lerena Mcmillan

2015-02-01

Full Text Available The present paper propose to investigate how the autobiographical subject is constructed in the text Carnets du voyage en Chine wich was written in 1974 by Roland Barthes. Another objective of this work will be indicate that Carnets can be understand as a space of problematization of the literary theory about the french autobiographical genre. The text of study will have as a distinctive mark the immediacy of living events in China and the time of his writing, where, the artifice of writing will allow the author construct themselves as a french man with a bourgeois formation in the context of the Great Chinese Proletarian Cultural Revolution. This context and details of the experience itself will set the tone of the story of Roland Barthes. We propose then, search the expression of the need to write as an organic need, and also as an imperative need of the bourgeois formation, who, at the same time rejects the subject but cannot ignored it.

EAMJ Jan. Dental 10.indd

African Journals Online (AJOL)

2010-01-01

Jan 1, 2010 ... Oral diseases qualify as a major public health concern owing to their high prevalence and incidence in all regions of the world (1). Dental caries and gingivitis are the two most common dental diseases affecting children worldwide. These two diseases are, to a large extent, the result of the presence of ...

Final Technical Report, 11 Jan 2013

International Development Research Centre (IDRC) Digital Library (Canada)

Ineke Buskens

2013-01-11

Jan 11, 2013 ... sub-projects in MENA focused on a wide range of ICTs and involved a wide variety of different ..... groundedness, reliability and applicability of their contributions. ..... “Yet even within this container, open sharing between the ...

Arte, imagem e fotografia: um diálogo possível entre Roland Barthes, Walter Benjamin e Jacques Rancière = Art, image and photography: a possible dialogue between Roland Barthes, Walter Benjamin and Jacques Rancière

Directory of Open Access Journals (Sweden)

Voigt, André Fabiano

2016-01-01

Full Text Available O presente artigo objetiva estabelecer um diálogo entre três autores que escreveram trabalhos importantes sobre a relação da arte com as imagens e a fotografia. Enquanto os pensamentos de Roland Barthes e Walter Benjamin se assemelham, Jacques Rancière apresenta uma postura dissonante ao analisar arte, imagem e fotografia no interior do que ele chama de regime estético das artes

Jan Uuspõld : "Mõnus on hommikul selge peaga ärgata!" / Eike Kingsepp

Index Scriptorium Estoniae

Kingsepp, Eike

2007-01-01

Näitlejast seoses peagi esilinastuva komöödiafilmiga "Jan Uuspõld läheb Tartusse", autorid Rain Tolk ja Andres Maimik : OÜ Kuukulgur Film. Lisaks sellest, kuidas näitleja filmi sattus : "Jan ja film"

PANORAMIC VIEW ON JAN ŠVANKMAJER'S CREATIVE OUTPUT

Directory of Open Access Journals (Sweden)

Boguslaw Zmudzinski

2007-01-01

Full Text Available Jan Švankmajer - is a leading world animation creator and confirmed representative representative of surrealism belonging to a small circle of film arts who, apart from great achievements in short animation, can also boast of remarkable attainments in long features. He owes it to his technique of combining animated and acting scenes together, which he developed already when making his short film forms. The article is a synthetic attempt at presentation of the artist's whole creative output starting from his first short animations from the 1960s up to his latest feature film titled Lunacy. The author of the text underlines the centrality of the object animation in the artistic work of Jan Švankmajer, who is the most outstanding representative of this form of animation alongside Jan Lenica, Walerian Borowczyk and Stephen and Timopthy Quay. In his latest film, the artist suggest with the kind of determination typical of the surrealists that all of his object animation production can be regarded as vision of a lunatic. Not many artist have courage to do so in the contemporary - and commercialized in the very nature of it - audiovisual culture.

Jazykovědec a pedagog Jan Balhar

Czech Academy of Sciences Publication Activity Database

Čižmárová, Libuše

2011-01-01

Roč. 94, č. 2 (2011), s. 101-103 ISSN 0027-8203 Institutional research plan: CEZ:AV0Z90610518 Keywords : Jan Balhar * dialectology * syntax * the Czech Linguistic Atlas * pedagogy Subject RIV: AI - Linguistics

U-series disequilibrium constraints on magma generation at the Jan Mayen hotspot

Science.gov (United States)

Rivers, E. R.; Chernow, R.; Elkins, L. J.; Sims, K. W.; Blichert-Toft, J.; Devey, C. W.

2013-12-01

The incompatible element-enriched magma source beneath the Jan Mayen Island hotspot influences melt generation on the adjacent northern Mid-Atlantic Ridge system and likely derives from either a small, local mantle plume, ancient Icelandic plume material emplaced in the mantle source, and/or sub-continental lithospheric mantle remnants emplaced locally by rifting of Greenland. The slow spreading Northern Kolbeinsey and Southern Mohns Ridges are immediately adjacent to Jan Mayen Island. Both have relatively shallow ridge axes, particularly the extremely shallow Eggvin Bank region of the Northern Kolbeinsey Ridge, which host anomalously large central volcanic edifices. We are currently collecting U-series disequilibrium and long-lived radiogenic isotope data for fresh, glassy mid-ocean ridge basalts from the Northern Kolbeinsey and Southern Mohns Ridge segments to better constrain source composition, depth of melting in the garnet peridotite stability field, solid mantle upwelling rates, and the nature of melt extraction beneath those segments. In particular, we are measuring isotopic data for geographically well-located samples collected from hummocky pillow basalt flows within the axial valley of the Northern Kolbeinsey Ridge segment as well as from the large volcanoes on both ridge segments, to further determine the role of the Jan Mayen hotspot in crustal construction on the Mid-Atlantic Ridge. Recently collected data show particularly high strontium isotope ratios consistent with trace element patterns that suggest a distinct local plume located beneath the Jan Mayen hotspot. A plume model for Jan Mayen is supported by new bathymetric imaging of adjacent ridge segments that reveals excess volcanism beneath the large axial volcanoes and a radial distribution of enrichment surrounding Jan Mayen Island. We predict that age-constrained U-series disequilibrium measurements will support active mantle upwelling focused beneath both Jan Mayen Island and the large axial

2003 - arhitektuurivõistluste tihe aasta / Pille Epner

Index Scriptorium Estoniae

Epner, Pille

2003-01-01

Tulemused: RMT Triigi metskonnahoone: I - A. Schults, Tallinna Muusikakeskkooli, Tallinna Balletikooli ja G. Otsa nim. Muusikakooli õppehoone: I - A. Siim, K. Ausing, "Kivilinn on ka elukeskkond": I - I. Järve, T. Sild, Tartu mnt. 63 juurdeehitus ja hoonestuse moderniseerimine: I - AB Kosmos ja A. Lember, J. Martson, R. Reinolt, Telliskivi t. ja Balti jaama vahelise ala ruumiline planeerimine: I - Tõnu Laigo, Tõnu Laanemäe, Kuressaare keskväljaku planeerimine ja kujundus: I - M. Pukk, I. Lubjak, Viimsi keskkooli uue hoone eskiislahendus: I - R. Järg, P. Pent, I. Truverk, Eesti Sisekaitseakadeemia õppelinnak: I - K. Koov, S. Vallner, K. Nõmm, Pärnu kesklinna koolide võimla: I - K. Koov, S. Vallner, K. Nõmm, Sakala keskus: I - I. Raukas, T. Teedumäe, T. Tammis, Merirahu elamupiirkond: I - AB Muru & Pere, parim puitehitis 1997-2003: I - A. Tambek, Pärnu Rüütli t. kujundus: I - T. Unt, TÜ sotsiaalteaduskonna õppehoone: II - K. Pae, Ü. Mark ja E. Kala, K. Kernumees, "Europan 7": I - Pärnu: O.-M. Bogdan, Tallinn: A. F. Atela

CERPEN FARUK “BUS KOTA” DALAM SEMIOTIK ROLAND BARTHES

Directory of Open Access Journals (Sweden)

Ken Widyatwati

2016-04-01

Full Text Available Literature called beautiful if it contains the mandate, message, ideas and meanings that are useful for the readers. Short story “Bus Kota” (City Bus containing the mandate, message, ideas and meanings that are useful to the reader. The mandate will be revealed by Roland Barthes' semiotic theory in the book S/Z. Literature has its own allure and text have accrued but not due to independence because of the difference in quality. Texts merge into a unity, or restore any text not as an individual but as a form of plurality. Literature as part of a social system is an expression of the author's sense of the outpouring of public life. Literary works can express themselves in the author's view the social and cultural changes in society because of the development of information technology and rapid. Technological developments and socio-cultural information can change in society so as to affect the psychology of the people. Society must have a thickness of faith not only for themselves, but to be able to maintain equanimity in the life of a pluralistic society

Jan Tschichold and the Language of Modernism.

Science.gov (United States)

Storkerson, Peter

1996-01-01

States that in "The New Typography," Jan Tschichold explicates a functionalist and information-based theory of typographic design and demonstrates its application in numerous typographic examples of varied genres. Outlines Tschichold's typographic position; analyzes his style of visual communication; and considers subsequent developments…

Carlos Aguirre Bastos y Roland R. Rebois, "Ciencia, Tecnología e Innovación: conceptos y prácticas" [book review

OpenAIRE

Fernández Vázquez, José María

1995-01-01

Este artículo reseña: Aguirre Bastos, Carlos y Roland R. Rebois. Ciencia, tecnología e innovación: conceptos y prácticas. Sucre (Bolivia), Proyecto de Monitoreo de Nuevas Tecnologías, Universidad Andina Simón Bolívar, Comisión Europea, 1994 Publicado

[Paulo Coelho. Zahir ; Jan Kaus. Tema] / Aarne Biin

Index Scriptorium Estoniae

Biin, Aarne

2007-01-01

Tutvustus: Coelho, Paulo. Zahir : [romaan] / portugali keelest tõlkinud Anneli Tuulik, [Konstantinos Kavafise luuletuse uuskreeka keelest tõlkinud Mati Sirkel. Tallinn] : Pilgrim Group, 2005 ; Kaus, Jan. Tema : [romaan]. Tallinn : Tuum, 2006

Kuidas ma pistiseskandaali sattusin / Jan Jõgis-Laats

Index Scriptorium Estoniae

Jõgis-Laats, Jan

2007-01-01

Eesti Ekspressis 27. septembril ilmunud artiklis kirjutatakse USA-s algatatud uurimisest Iraagi ülesehitusprogrammi raha võimaliku väärkasutamise üle. Jan Jõgis-Laats kirjeldab sündmuste jada, et selgitada selle loo tausta, millesse on väidetavalt ka tema kaasatud

Open Source Software and Open Content: Interview met Jan Hylén

NARCIS (Netherlands)

Lambert Berenbroek

2005-01-01

Jan Hylén also attending the Surf Education Days 2005, held a presentation about Open Source Software and Open Content (such as the MIT Open Courseware project and the Open Access initiative). Jan Hylén is working at the Centre for Educational Research and Innovation (CERI) of the Organization of

Jan Mukařovský and Theatre

Czech Academy of Sciences Publication Activity Database

Sládek, Ondřej

2014-01-01

Roč. 17, č. 2 (2014), s. 122-136 ISSN 1803-845X R&D Projects: GA ČR GAP406/10/1911 Institutional support: RVO:68378068 Keywords : Mukařovský, Jan * theatre * structuralism * theory of theatre * theatre criticism Subject RIV: AJ - Letters, Mass-media, Audiovision

Self-assembled micelles based on pH-sensitive PAE-g-MPEG-cholesterol block copolymer for anticancer drug delivery

Directory of Open Access Journals (Sweden)

Zhang CY

2014-10-01

Full Text Available Can Yang Zhang, Di Xiong, Yao Sun, Bin Zhao, Wen Jing Lin, Li Juan Zhang School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, Guangdong Province, People’s Republic of China Abstract: A novel amphiphilic triblock pH-sensitive poly(ß-amino ester-g-poly(ethylene glycol methyl ether-cholesterol (PAE-g-MPEG-Chol was designed and synthesized via the Michael-type step polymerization and esterification condensation method. The synthesized copolymer was determined with proton nuclear magnetic resonance and gel permeation chromatography. The grafting percentages of MPEG and cholesterol were determined as 10.93% and 62.02%, calculated from the area of the characteristic peaks, respectively. The amphiphilic copolymer was confirmed to self-assemble into core/shell micelles in aqueous solution at low concentrations. The critical micelle concentrations were 6.92 and 15.14 mg/L at pH of 7.4 and 6.0, respectively, obviously influenced by the changes of pH values. The solubility of pH-responsive PAE segment could be transformed depending on the different values of pH because of protonation–deprotonation of the amino groups, resulting in pH sensitivity of the copolymer. The average particle size of micelles increased from 125 nm to 165 nm with the pH decreasing, and the zeta potential was also significantly changed. Doxorubicin (DOX was entrapped into the polymeric micelles with a high drug loading level. The in vitro DOX release from the micelles was distinctly enhanced with the pH decreasing from 7.4 to 6.0. Toxicity testing proved that the DOX-loaded micelles exhibited high cytotoxicity in HepG2 cells, whereas the copolymer showed low toxicity. The results demonstrated how pH-sensitive PAE-g-MPEG-Chol micelles were proved to be a potential vector in hydrophobic drug delivery for tumor therapy. Keywords: micelle, pH-sensitive, cholesterol, poly(ß-amino ester, drug delivery

Cohen-Cruz, Jan (org., Radical Street Performance: An International Anthology

Directory of Open Access Journals (Sweden)

Cláudia Pato de Carvalho

2012-10-01

Full Text Available Jan Cohen-Cruz foi membro do New York City Street Theatre/Jonah Project entre 1971 e 1972. Organizou workshops de teatro em prisões, hospitais psiquiátricos e centros comunitários. É co-organizadora de Playing Boal: Theatre, Therapy, Activism e os seus artigos, baseados na performance activista e performance comunitária, foram publicados nas revistas TDR, High Performance, American Theatre, Urban Resources, Women and Performance, The Mime Journal e na antologia But Is It Art?. Jan é também pr...

Jan Culik on the Scottish independence referendum

OpenAIRE

Culik, Jan

2014-01-01

A live interview with Jan Culik on the results and the political circumstances of the referendum on Scottish independence, broadcast from the BBC Pacific Quay studios. The interview was transmitted on Friday 19th September, 2014, by the nationwide Czech public service Radio (Radiozurnal) from 10 to 11 am.

Editorial The Jan H. Stock Valedictory Issue

NARCIS (Netherlands)

NN,

1990-01-01

Professor Jan H. Stock, an inspiring zoologist of international fame (born 22 February 1931), will retire from the University of Amsterdam at the end of this year. It is his wish to settle in his beloved island Curaçao in the Netherlands Antilles and there to continue his taxonomic and zoogeographic

Ready for the challenge. The IAEA Bulletin talks to Jan Eliasson

International Nuclear Information System (INIS)

2005-01-01

Jan Eliasson, Sweden's Ambassador to the US since 2000, will become the next president of the United Nations General Assembly for its 60th session beginning in September 2005. Eliasson served as Sweden's ambassador to the UN from 1988-1992 and was appointed the first Under Secretary General for Humanitarian Affairs of the UN in 1992. He speaks about his new job, UN reform, and his hopes for the future.The IAEA Bulletin interview with Mr. Jan Eliasson is presented in this article

AMOR COM HUMOR: A RECRIAÇÃO DO EPITALÂMIO NA POESIA DE JOSÉ PAULO PAES

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Renan Pires Cornette

2013-12-01

Full Text Available One of the characteristics of the poetry of José Paulo Paes is the recuperation of classical traditional forms adjusting the models of the past to his personal diction by using critical dislocation. This occurs with the epithalamium, a lyrical composition that was originally practiced by the Greeks in honor of newlyweds. Amongst the Romans it took on a pornographic character and was ratified traditionally by self-seeking flattery. This article proposes to analyze three epithalamiums written by the poet, seeking to show the traces of difference inserted by the poet in this classical lyric form.

Jan Gehli teose "Linnad inimestele" ilmumine = Publication of an Estonian-language Edition of Jan Gehl's Cities for People / Yoko Alender, Liina Teder, Neeme Lopp

Index Scriptorium Estoniae

Alender, Yoko, 1979-

2016-01-01

Taani arhitektist Jan Gehlist ja tema raamatust "Linnad inimestele". Eestikeelse väljaande toimkond: Yoko Alender, Neeme Lopp, Liina Teder, Eneli Rohtla. Maastikuarhitektuuri aastapreemia nominent 2016

A prospective cohort study comparing the VAS spine score and Roland-Morris disability questionnaire in patients with a type A traumatic thoracolumbar spinal fracture

NARCIS (Netherlands)

Siebenga, J.; Leferink, V. J. M.; Segers, M. J. M.; Elzinga, M. J.; Bakker, F. C.; Ten, Duis H. J.; Rommens, P. M.; Patka, P.

The Roland Morris Disability Questionnaire (RMDQ-24) and the VAS spine score have been regularly used to measure functional outcome in patients with back pain. The RMDQ-24 is primarily used in degenerative disease of the spine and the VAS Spine is used in trauma patients. The aim of this study is to

Oscar Masotta y Roland Barthes. Homologías estructurales de una crítica de vanguardia

Directory of Open Access Journals (Sweden)

Max Hidalgo Nácher

2015-06-01

Full Text Available El artículo propone una lectura comparada de la obra de Oscar Masotta y de Roland Barthes hasta los años setenta. Beatriz Sarlo y Pierre Bourdieu han visto en estos autores, respectivamente, un síntoma de la época. Así, más que fijarnos en sus contenidos, proponemos una lectura en movimiento a partir del descubrimiento de una homología estructural: Masotta y Barthes comparten una misma posición de enunciación. Como podrá verse en el artículo, ésta va ligada, a su vez, a la precariedad de su posición institucional y a una apuesta decidida por la vanguardia intelectual.

50 Years of Health Physics Section of the Roland Eotvos Physical Society

International Nuclear Information System (INIS)

Andrasi, A.; Deme, A.; Feher, I.

2013-01-01

The Health Physics Section of the Roland Eötvös Physical Society (Hungary) was founded 50 years ago in March 1962 by eighty radiation protection specialists. The main goal from the most beginning is to provide forum for people working in radiation protection in Hungary aiming at safe application of ionizing radiation and of atomic energy. Our Section is the member of IRPA since the first IRPA General Assembly (7 September 1966). The second European Regional Congress of IPRA was held in Budapest in 1972. Recently the Section has about 160 members. The permanent forms of our activities are: organisation every year of a 3-day upgrading course in radiation protection. The first course was held in 1976, last year (2012) we had the 37th course in Hajdúszoboszló, Hungary, regular issue of Radiation Newsletters, up to now 51 numbers, on-line paper Radiation Protection serves for publication of results, book on Radiation Protection (in Hungarian) got out in 2010, international cooperation in radiation with neighbouring countries including CRPA. Our paper presents other achievements of the Section as well.(author)

Assessing self-reported disability in a low-literate population with chronic low back pain: cross-cultural adaptation and psychometric testing of Igbo Roland Morris disability questionnaire.

Science.gov (United States)

Igwesi-Chidobe, Chinonso N; Obiekwe, Chinwe; Sorinola, Isaac O; Godfrey, Emma L

2017-12-14

Cross-culturally adapt and validate the Igbo Roland Morris Disability Questionnaire. Cross-cultural adaptation, test-retest, and cross-sectional psychometric testing. Roland Morris Disability Questionnaire was forward and back translated by clinical/non-clinical translators. An expert committee appraised the translations. Twelve participants with chronic low back pain pre-tested the measure in a rural Nigerian community. Internal consistency using Cronbach's alpha; test-retest reliability using intra-class correlation coefficient and Bland-Altman plot; and minimal detectable change were investigated in a convenient sample of 50 people with chronic low back pain in rural and urban Nigeria. Pearson's correlation analyses using the eleven-point box scale and back performance scale, and exploratory factor analysis were used to examine construct validity in a random sample of 200 adults with chronic low back pain in rural Nigeria. Ceiling and floor effects were investigated in the two samples. Modifications gave the option of interviewer-administration and reflected Nigerian social context. The measure had excellent internal consistency (α = 0.91) and intraclass correlation coefficient (ICC =0.84), moderately high correlations (r > 0.6) with performance-based disability and pain intensity, and a predominant uni-dimensional structure, with no ceiling or floor effects. Igbo Roland Morris Disability Questionnaire is a valid and reliable measure of pain-related disability. Implications for rehabilitation Low back pain is the leading cause of years lived with disability worldwide, and is particularly prevalent in rural Nigeria, but there are no self-report measures to assess its impact due to low literacy rates. This study describes the cross-cultural adaptation and validation of a core self-report back pain specific disability measure in a low-literate Nigerian population. The Igbo Roland Morris Disability Questionnaire is a reliable and valid measure of self

Levi-Strauss Ve Roland Barthes’ın Yaklaşımıyla “God Of War III” Oyununun Mitsel Çözümlemesi

OpenAIRE

SEPETÇİ, Tülin

2016-01-01

Bu çalışmanın amacı, Roland Barthes ve Levi-Strauss’un mit kuramlarını bir popüler kültür ürünü olarak ele alınan “God of War III” adlı video oyunu bağlamında karşılaştırmaktır. Çalışmada öncelikle tarihsel süreç içerisinde mitlerin işlevi ve “oyun” kavramının mitlerle ilişkisinden, ardından Levi-Strauss ve Roland Barthes’ın mit yaklaşımları ve analizinden bahsedilmiş, ardından “God of War III” adlı video oyununa mitsel çözümleme yapılmıştır. Her iki düşünürün mit yaklaşımları çerçevesinde ön...

Arhitekt Jan Verwijnen - Euroopa urbanist, kes pani aluse Eesti Kunstiakadeemia linnauuringute programmile : in memoriam / Panu Lehtovuori

Index Scriptorium Estoniae

Lehtovuori, Panu, 1968-

2005-01-01

Jan (Johannes) Verwijnen sündis Hollandis Haagis 19. VIII 1949, suri Helsingis 14. X 2005. Jan Verwijneni tööst Hollandis ja Soomes, külaskäikudest Eestisse. 2004. a. pani ta aluse urbanistika magistriprogrammile Eesti Kunstiakadeemias

The Jan Deyl Conservatory and 105 years since the opening of the Deyl Institute for the Blind

Czech Academy of Sciences Publication Activity Database

Vytlačil, Lukáš

č. 4 (2015), s. 18-20 ISSN 1211-0264 Institutional support: RVO:68378076 Keywords : conservatories * music schools * blind s * Jan Deyl * Jiří Drtina * Jan Deyl Conservatory Subject RIV: AL - Art, Architecture, Cultural Heritage

Jan Amos Komenský - tänapäeva alushariduse suur eelkäija

Index Scriptorium Estoniae

2014-01-01

Tutvustus: Jan Amos Komenský. Didactica magna : Stora undervisningsläran, Göteborg, 1989 ; Jan Amos Komenský. Orbis sensualium pictus quadrilinguis : hoc est: omnium fundamentalium, in mundo rerum & in vita actionum, pictura & nomenclatura latina, germanica, hungarica & bohemica, Praha ; Bratislava, 1958. Tallinna Ülikooli pedagoogilise seminari üliõpilased Triinu Lüüde ja Anneli Virves lugesid teoseid inglise keeles ning esinesid ettekannetega Tallinna Ülikooli pedagoogilise seminari 2. kasvatuse ajaloo konverentsil

A 900 MHz, 21 dBm CMOS linear power amplifier with 35% PAE for RFID readers

Energy Technology Data Exchange (ETDEWEB)

Han Kefeng; Cao Shengguo; Tan Xi; Yan Na; Wang Junyu; Tang Zhangwen; Min Hao, E-mail: tanxi@fudan.edu.cn [State Key Laboratory of ASIC and System, Fudan University, Shanghai 201203 (China)

2010-12-15

A two-stage differential linear power amplifier (PA) fabricated by 0.18 {mu}m CMOS technology is presented. An output matching and harmonic termination network is exploited to enhance the output power, efficiency and harmonic performance. Measurements show that the designed PA reaches a saturated power of 21.1 dBm and the peak power added efficiency (PAE) is 35.4%, the power gain is 23.3 dB from a power supply of 1.8 V and the harmonics are well controlled. The total area with ESD protected PAD is 1.2 x 0.55 mm{sup 2}. System measurements also show that this power amplifier meets the design specifications and can be applied for RFID reader. (semiconductor integrated circuits)

A 900 MHz, 21 dBm CMOS linear power amplifier with 35% PAE for RFID readers

International Nuclear Information System (INIS)

Han Kefeng; Cao Shengguo; Tan Xi; Yan Na; Wang Junyu; Tang Zhangwen; Min Hao

2010-01-01

A two-stage differential linear power amplifier (PA) fabricated by 0.18 μm CMOS technology is presented. An output matching and harmonic termination network is exploited to enhance the output power, efficiency and harmonic performance. Measurements show that the designed PA reaches a saturated power of 21.1 dBm and the peak power added efficiency (PAE) is 35.4%, the power gain is 23.3 dB from a power supply of 1.8 V and the harmonics are well controlled. The total area with ESD protected PAD is 1.2 x 0.55 mm 2 . System measurements also show that this power amplifier meets the design specifications and can be applied for RFID reader. (semiconductor integrated circuits)

Provisional PDF Published Jan 26, 2010 Research, Volume 4, Issue ...

African Journals Online (AJOL)

cqq1a

2010-01-26

Jan 26, 2010 ... Conclusion: The estimated cost of treatment for chronic suppurative otitis media is ... health problem in children and adults in Africa, Asia and Latin America [1]. ... (Mean age=9.23 years, SD=7.92), accounting for 31.1% of all ...

Comput digital and Jan Hus as defender of the faith

Czech Academy of Sciences Publication Activity Database

Šroněk, Michal

2013-01-01

Roč. 61, č. 1 (2013), s. 2-22 ISSN 0049-5123 Institutional support: RVO:68378033 Keywords : Jan Hus * comput digital * utraquist iconography Subject RIV: AL - Art, Architecture, Cultural Heritage http://www.umeni-art.cz/cz/issue-detail.aspx?v=issue-issue-1712

Describing the self through the photographic medium: the autobiographic fictions of John M. Coetzee, Roland Barthes and Edward Said

Directory of Open Access Journals (Sweden)

Sandra Lila Maya Rota

2012-01-01

Full Text Available The present study investigates the different approaches to autobiography of three writers – John M. Coetzee, Edward Said and Roland Barthes – who are divided by background and historical circumstances but share the terrain of postcolonial and postmodern theory. In particular, the focus is on the use they make of photographs – real or evoked – that accompany their personal accounts. Using photography as a counterpoint and a parallel to autobiography, they all try and come to terms with issues of subjectivity, representation and authenticity. As a result, their life-long convictions will be challenged by the power of memory, leaving way to a renewed sense of self.

Popkultuurgi on rahvuskultuuri osa / Valle-Sten Maiste ja Jan Kaus

Index Scriptorium Estoniae

Maiste, Valle-Sten, 1972-

2009-01-01

Õnnestunud muusikafestival Tallinn Music Week tõstatas olulisi kultuuripoliitilisi küsimusi. Jan Kaus ja Valle-Sten Maiste arutlevad artiklis selle üle, et popkultuur vajaks hariduse ja tugistruktuuride näol toestamist, tuleks tunnustada kodumaist väärt pop- ja rockmuusikat

Exploring the boundaries of individual and collective land use management: institutional arrangements in the PAE Chico Mendes (Acre, Brazil

Directory of Open Access Journals (Sweden)

François-Michel Le Tourneau

2017-03-01

Full Text Available The economic modernization of the Amazon fostered by the Brazilian military government during the 1960s and 1970s was largely realized without taking into consideration the presence of local households which lived from the extraction of forest products (mainly non-timber. When they began to be expulsed, a political resistance, often guided by the Catholic Church, appeared as well as the creation of unions based on traditional identities, especially that of rubber tappers. During the 1980s, these unions made a strategic alliance with the ecologist movement which started to consider traditional populations, whose lifestyle depended on the forest, as allies for the protection of the Amazon rainforest. The movement gained a decisive momentum at the end of the decade by putting forward new proposals of land tenure for traditional populations, grounded on collective land rights. This strategy has been very efficient during the 1990s and 2000s, during which about 1,300,000 km2 of rainforest were set apart and reserved for the use of “traditional communities” under a variety of legal status. But it has also led to mix under the same “collective” etiquette and principles a number of different ways of using and managing land and natural resources. This assumption however should be nuanced by a careful analysis of the resource management systems existing in each case, for they are in general complex and mix varying proportions of individual and collective decisions. The aim of this paper is to explore this question using the example of the Chico Mendes agroextractive settlement (PAE-CM, inhabited by about 100 rubber tapper families and symbolic of the political struggle of traditional populations in the Amazon for being the home of the rubber tapper leader Chico Mendes assassinated in 1988. Applying Ostrom “design principles”, we try to catch what are the local institutional arrangements and to see if they suggest

Stalkerid sisekujundusmaastikul / Jan Joonas Graps, Ken-Kristjan Ruut ; intervjueerinud Aale Kask

Index Scriptorium Estoniae

Graps, Jan Joonas, 1972-

2008-01-01

Sisearhitektide Jan Joonas Grapsi ja Ken-Kristjan Ruudu loomingust, tehtud tööde loetelu. Sarjast WooDoo. Pelgulinnas Kaera 22 asuva korteri (arhitekt Harry Klaar) ja Murastes asuva eramu (arhitekt Mart Kadarik) sisekujundusest

Author in cyberspace: comparison of the current position of the author and authorship anonymity with theories of Michel Foucault and Roland Barthes

OpenAIRE

Bobák, Alexander

2015-01-01

This thesis analyzes the position of the author in the environment of internet. The main source of information for this thesis is the study of Roland Barthes - Death of the Author and the lecture of Michel Foucault - What is an author? After a thorough analysis of these two works, the thesis focuses on the description of the webpage www.pismak.cz, which has been selected as a suitable representative for environment of internet. This website allows us to study and explore the role and place of...

Arvustuse piirid ja auhinnad : mõtteid kirjanduskriitikast vol 2 / Jan Kaus

Index Scriptorium Estoniae

Kaus, Jan, 1971-

2007-01-01

Tänapäeva eesti kirjanduskriitikast. Vt. ka vol. 1: Kaus, Jan. Eetika, taburetiefekt ja jätkuv objektivisatsioon, Sirp, 15. juuni., lk. 7. Vastukaja: Raudam, Toomas. Arvustuse piiritused //Sirp (2007) 10. aug., lk. 9

Trading economics across the Atlantic : Jan Tinbergen for Milton Friedman

NARCIS (Netherlands)

van Dalen, H.P.; Klamer, A.; Krabbendam, H.; van Minnen, C.A.; Scott-Smith, G.

2009-01-01

Jan Tinbergen and Milton Friedman were both very much inspired making economic theory work, applying it in service of society. The Tinbergen approach - the economist as Social Engineer - was exported to Chicago in the 1940s where one of Tinbergen’s students - Tjalling Koopmans - became a prominent

Chtivost architektury. Autobiografické zápisky Pavla Janáka

Czech Academy of Sciences Publication Activity Database

Hnídková, Vendula

2009-01-01

Roč. 57, č. 5 (2009), s. 477-494, 513 ISSN 0049-5123 Institutional research plan: CEZ:AV0Z80330511 Keywords : Pavel Janák * Czech architecture * autobiography Subject RIV: AL - Art, Architecture, Cultural Heritage

37.pdf | jan102006 | currsci | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; currsci; jan102006; 37.pdf. 404! error. The page your are looking for can not be found! Please check the link or use the navigation bar at the top. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. 29th Mid-year meeting. Posted on 19 January 2018. The 29th Mid-year meeting of the Academy will be held ...

Srovnání herních charakteristik tenistů a tenistek na Roland Garros 2005 Comparison of game characteristics of male and female tennis players at Roland Garros 2005

Directory of Open Access Journals (Sweden)

Tomaž Berendijaš

2008-04-01

Full Text Available Herní charakteristiky elitních tenistů a tenistek na French Open 2005 (Roland Garros byly analyzovány na rozsáhlém základě 894 setů v kategorii mužů a 592 setů v kategorii žen. Navíc se srovnávaly herní charakteristiky jednotlivého setu mezi vítězi a poraženými. Bylo potvrzeno, že u většiny proměnných existují statisticky významné rozdíly mezi vítězi a poraženými, a to jak v kategorii mužů, tak i žen. V kategorii mužů jsou statisticky významné rozdíly u všech proměnných, s výjimkou využití brejkbolu. U žen byly shledány statisticky významné rozdíly u všech proměnných s výjimkou počtu vyhraných es. Na základě těchto zjištění lze učinit závěr, že statisticky významné rozdíly u většiny proměnných určujících herní charakteristiky naznačují existenci určitých měřitelných ukazatelů ve statistice tenisu, kterými se odlišují vítězové od poražených. The game characteristics of elite male and female tennis players at the French Open 2005 (Roland Garros have been analyzed based on a large number of sets, a total of 894 in the category of men and 592 sets in the category of women. In addition, a comparison of game characteristics in an individual set between winners and losers has been made. It was ascertained that there are statistically characteristic differences in most variables between the winners and loser in the category of men as well as in the category of women. In the category of men, there are statistically characteristic differences in all variables except in the break point conversions. In women however, there are statistically characteristic differences in all variables except in the number of won aces. Based on these findings it can be concluded that statistically characteristic differences in the majority of variables, which define game characteristics, indicate that there are certain measurable indicators of tennis statistics, which distinguish

Msgre. Jan Šrámek a Msgre. Andrej Hlinka

Czech Academy of Sciences Publication Activity Database

Pehr, Michal

2014-2015, [1] (2016), s. 199-211 ISSN 1214-8334 Institutional support: RVO:67985921 Keywords : Šrámek, Jan * Hlinka, Andrej * Czechoslovakia, 1918-1938 Subject RIV: AB - History OBOR OECD: History (history of science and technology to be 6.3, history of specific sciences to be under the respective headings)

Monitoring of PAEMs and beta-agonists in urine for a small group of experimental subjects and PAEs and beta-agonists in drinking water consumed by the same subjects.

Science.gov (United States)

Liou, Saou-Hsing; Yang, Gordon C C; Wang, Chih-Lung; Chiu, Yu-Han

2014-07-30

This 5-month study contains two parts: (1) to monitor the concentrations of 11 phthalate esters metabolites (PAEMs) and two beta-agonists in human urine samples collected from a small group of consented participants including 16 females and five males; and (2) to analyze the residues of phthalate esters (PAEs) and beta-agonists in various categories of drinking water consumed by the same group of subjects. Each category of human urine and drinking water had 183 samples of its own. The analytical results showed that nine PAEMs were detected in human urine and eight PAEs were detected in drinking water samples. It was found that average concentrations of PAEMs increased as the age increased, but no significant difference between sexes. Further, using the principal component analysis, the loadings of age effect were found to be two times greater than that of gender effect in terms of four DEHP metabolites. Regarding beta-agonists of concern (i.e., ractopamine and salbutamol), they were neither detected in human urine nor drinking water samples in this study. Copyright © 2014 Elsevier B.V. All rights reserved.

Digitaalse arengu eestvedaja Rootsis - digitšempion professor Jan Gulliksen / Tauno Otto

Index Scriptorium Estoniae

Otto, Tauno, 1967-

2016-01-01

Tallinna tehnikaülikoolis pidas 22. aprillil avaliku loengu Rootsi kuningliku tehnikaülikooli dekaan, professor Jan Gulliksen. Loengu teema oli, kuidas Rootsi edendab digitaliseerimist nii hariduses kui ka tööstuses

Evaluation of the effectiveness of short-term rehabilitation of women with chronic low back pain using the Oswestry and Roland-Morris Disability Scales.

Science.gov (United States)

Topolska, Marta; Sapuła, Rafał; Topolski, Adam; Marczewski, Krzysztof

2011-01-01

60-80% of the population experience chronic low back pain at some point in their lives [1], with women suffering more frequently [2]. Low back pain-related ailments lead to long-term or recurrent disability [3, 4]. Rehabilitation based on physiotherapy provides a viable alternative and is rightly regarded as safer for patients. However, finding an effective method of rehabilitation is a difficult task [5, 6]. The aim of this study was to compare the outcomes of rehabilitation in women with chronic low back pain using the Oswestry and Roland-Morris Disability Scales and to identify factors influencing the degree of functional disability in patients with chronic low back pain. The study involved 319 women aged 18-75 years (mean age = 45 years, SD ± 16. 3). The participants were undergoing treatment at the Rehabilitation Centre of Zamość University of Management and Administration on account of chronic low back pain, following two or more episodes lasting longer than three months. The outcomes of rehabilitation were assessed with ODI and RMDQ. We obtained comparable results with the ODI and RMDQ and found statistically significant improvement in functional status after rehabilitation (ODI: p disability and age (ODI: p disability vs. place of residence (ODI: p disability, as demonstrated both by the Oswestry Disability Index and the Roland-Morris Disability Questionnaire. 2. The relationship between the degree of functional disability and age, BMI, WHR, and hypertension was also confirmed by both questionnaires.

Personnel dosimetry: specialized industrial services. Jan 1997-Aug 2001

International Nuclear Information System (INIS)

Guillen, J.A.

2001-09-01

The purpose of this report is to evaluate data from personnel dosimetry of the Servicios Industriales Especializados, that is a licensee with gamma sources for non destructive testing. Data of the period Jan-97 to Aug-01 are evaluated in terms of collective doses. This report was made according to the national regulations that stablish to control that annual limits and reference levels in personnel dosimetry must be controlled

A destruição da imaginação e a permanência da utopia: Desenvolvimento, Tecnologia e Cultura em Roland Corbisier

OpenAIRE

Queluz, Gilson Leandro; Merkle, Luiz Ernesto

2014-01-01

Abordamos neste texto algumas das reflexões desenvolvidas por Roland Corbisier sobre as técnicas em suas relações com as sociedades. Com destaque aos seus escritos do período da ditadura militar, procuraremos demonstrar que Corbisier problematizou temáticas que envolviam as relações entre tecnologia, desenvolvimento e cultura, técnica e colonialismo, técnica e política, tecnologia e imaginação, técnica e violência, dentre outras. Constatamos o trânsito de Corbisier de uma percepção marcadamen...

154.pdf | 25jan2011 | currsci | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; currsci; 25jan2011; 154.pdf. 404! error. The page your are looking for can not be found! Please check the link or use the navigation bar at the top. YouTube · Twitter · Facebook · Blog. Academy News. IAS Logo. Ethical Guidelines and Procedures document. Posted on 17 January 2017. A revised version of the ...

Remembering Jan Svoboda: A Personal Reflection.

Science.gov (United States)

Weiss, Robin A

2018-04-18

The Czech scientist Jan Svoboda was a pioneer of Rous sarcoma virus (RSV). In the 1960s, before the discovery of reverse transcriptase, he demonstrated the long-term persistence of the viral genome in non-productive mammalian cells, and he supported the DNA provirus hypothesis of Howard Temin. He showed how the virus can be rescued in the infectious form and elucidated the replication-competent nature of the Prague strain of RSV later used for the identification of the src oncogene. His studies straddled molecular oncology and virology, and he remained an active contributor to the field until his death last year. Throughout the 50 years that I was privileged to know Svoboda as my mentor and friend, I admired his depth of scientific inquiry and his steadfast integrity in the face of political oppression.

Spuren des Nibelungenlieds in Jan Erazim Vocels Přemyslovci (1839)

Czech Academy of Sciences Publication Activity Database

Krejčová, Iva; Wögerbauer, Michael

2011-01-01

Roč. 22, č. 1 (2011), s. 30-46 ISSN 1210-9029 Institutional research plan: CEZ:AV0Z90560517 Keywords : Czech literature * German literature * poem cycle The Premyslides * Vocel, Jan Erazim * Nibelungenlied verse * the Niebelung lay * Schlegel brothers * Dvůr Králové and Zelená hora manuscripts * interpretation * epic heroic poetry Subject RIV: AJ - Letters, Mass-media, Audiovision

Jan Dullaert of Ghent on the Foundations of Propositional Logic

Czech Academy of Sciences Publication Activity Database

Hanke, Miroslav

2017-01-01

Roč. 55, č. 4 (2017), s. 273-306 ISSN 0042-7543 R&D Projects: GA ČR GB14-37038G Institutional support: RVO:67985955 Keywords : Jan Dullaert of Ghent * the circle of John Mair * scholastic logic * propositional logic * Bradwardine’s principle * infinite expressions Subject RIV: AA - Philosophy ; Religion OBOR OECD: Philosophy, History and Philosophy of science and technology

Diathesis sotto tensione. La sala per concerti del Centro culturale di Atene di Jan Despo / Diathesis under Tension. Concert Theatre of the Athens Cultural Center by Jan Despo

Directory of Open Access Journals (Sweden)

Tilemachos Adrianopoulos

2016-04-01

Full Text Available Nel 1959, l'architetto greco Jan Despo (1903-1992 fu insignito del primo premio nella competizione per il Centro culturale di Atene, rimasto irrealizzato eccezion fatta per il Conservatorio di Atene. La sala circolare per concerti, danza e conferenze era l'edificio nodale di una ambiziosa composizione urbana: la sbalorditiva forma geometrica della sala, la funzione tipicamente composita e l'ingegnosa conformazione strutturale furono integralmente concepite all'interno di una "diathesis spaziale". / In 1959, Greek architect Jan Despo (1903-1992 was awarded First Prize in the competition for the Athens Cultural Centre -that remained unrealized, however, with the exception of the Athens Conservatory. The circular concert, dance and conference theatre was the nodal building of an ambitious urban composition: the theatre’s stunning geometric form, distinctively composite function and ingenious structural conformation were all integrally conceived—within an essentially tense spatial diathesis.

Olemuse teater. Kantor ja Brook / Jan Kott ; tõlk. Eva-Liisa Linder

Index Scriptorium Estoniae

Kott, Jan

2004-01-01

T. Kantori lavastustest "Surnud klass" ja "Wielopole Wielopole" ning P. Brooki "Carmeni" lavastusest. Tõlgitud raamatust : Jan Kott. The Theatre of Essence: Kantor and Brook.- The Theatre of Essence and other Essays. Evanston, Northwestern University Press, 1984, lk. 159-165

De Amsterdamse bouwmeester en landmeter Jan Jacobszoon Bolten (1738-na 1811)

NARCIS (Netherlands)

von der Dunk, T.H.

2013-01-01

The Amsterdam architect and surveyor Jan Jacobszoon Bolten (1738-after 1811) is one of many private architects whose name pops up now and then in the literature. This essay, for the first time, sketches his quite varied career. Since mid-1768 he held the post of architect and surveyor in the

Universal Music Finlandi kontoriruumid = Offices of Universal Music Finland / Jan Skolimowski ; intervjueerinud Margit Mutso

Index Scriptorium Estoniae

Skolimowski, Jan, 1977-

2011-01-01

Helsingis Merimiehenkatu 36D asuvate kontoriruumide sisekujundusest. Sisearhitekt Jan Skolimowski, kaasautor Peeter Loo (KAMP Arhitektid OÜ). Graafilise disaini autor Martin Eelma (Tuumik Stuudio OÜ)

Representasi Maskulinitas Dalam Iklan Televisi Pond’s Men #Lelakimasakini (Analisis Semiotika Roland Barthes Terhadap Representasi Maskulinitas

Directory of Open Access Journals (Sweden)

Friska Dewi Yuliyanti

2017-07-01

Full Text Available This research aims to know the meaning of denotation, the connotation and the myth or ideology in television commercials POND'S Men that represent the masculine with #LelakiMasaKini edition. The method used in this research is the Semiotic analysis methods. The Semiotic analysis used in this research is the Semiotic Roland Barthes. The results of this research show that there are; meaning denote, the connotation and the myth or ideology in television commercials POND'S #LelakiMasaKini. The results obtained from the signs of the dominant in the preview scenes that are taken in accordance with the criteria that have been determined. Advertising on Rio Dewanto version described three meaning denotes, three meaning of the connotations and three myths. On the version of the advertisement, Keenan Pearce described three meaning denotes, three the meaning of the connotations and three myths or ideologies and on the version of the Marshall Sastra described three meaning denotes, three the meaning of the connotations and 3 myths or ideologies. Concluded the side or the form of masculinity is promoted of the physical appearance of the type of men who tend to metrosexual, the dream of women, the leader success, lack men who think creatively and have hobbies. Penelitian ini bertujuan untuk mengetahui makna denotasi, konotasi serta mitos atau ideologi dalam iklan televisi POND’S Men yang merepresentasikan maskulinitas dengan edisi #LelakiMasaKini. Metode yang digunakan dalam penelitian ini adalah metode analisis semiotik. Analisis Semiotik yang digunakan dalam penelitian ini adalah analisis semiotik Roland Barthes. Hasil dari penelitian ini menunjukkan bahwa terdapat makna denotasi, konotasi serta mitos atau ideologi pada iklan televisi POND’S Men #LelakiMasaKini. Hasil itu diperoleh dari tanda-tanda dominan pada cuplikan adegan-adegan yang diambil sesuai dengan kriteria yang telah ditentukan. Pada iklan versi Rio Dewanto digambarkan 3 makna denotasi, 3

Plastic raakt zoek in de oceaan (interview met Jan Andries van Franeker)

NARCIS (Netherlands)

Kleis, R.; Franeker, van J.A.

2015-01-01

De plastic eilanden op de oceanen verliezen in hoog tempo .....plastic. Jan Andries van Franeker toont dat aan door plastic vangsten in die eilanden te vergelijken met de maaginhoud van Noordse stormvogels op de Noordzee. Waar al dat plastic blijft, is vooralsnog een raadsel.

Aeg kui intermeedium : juhukohtumine Jan Kaila ja Daniel de Chenuga / Peeter Linnap

Index Scriptorium Estoniae

Linnap, Peeter, 1960-

2012-01-01

Soome kunstniku Jan Kaila ja iiri kunstniku Daniel de Chenu näitusest "Nüüd ja siis" 2003. a. Tallinna Kunstihoone galeriis. J. Kaila installatsioonis "Ümber pöörata/To Turn Around" on kesksel kohal portreed soome harrastuskunstnikust Elis Sinistöst

Vabaõhulavastuse "Jõujaam" proovid käivad täie hooga / Jan Rahman

Index Scriptorium Estoniae

Rahman, Jan, 1975-

2007-01-01

Leevaku hüdroelektrijaama juures etendub jaanipäeva paiku Jan Rahmani kirjutatud näitemäng "Jõujaam", lavastaja Raivo Adlas. Mängib Räpina näitemänguseltskond. Näitekirjanik tutvustab lavastust

The impact of prostate artery embolization (PAE) on the the physical history and pathophysiology of benign prostatic hyperplasia (BPH).

Science.gov (United States)

Stamatiou, Konstantinos

2018-03-31

Prostate artery embolization (PAE) is a non invasive modality for the treatment of benign prostate hypertrophy (BPH) related lower urinary tract symptoms (LUTS). As a relatively new procedure, data determining the clinical success is somehow scarce. In the present article we examine the current clinical outcome measures in order to identify the most accurate. Current imaging outcome measures are consistent with clinical ones only in the group of patients with adenomatous- dominant BPH while are inconsistent in patients with small sized adenomas. Additional studies and/or evaluation tools are needed in order to provide accurate evaluation of clinical success in the subgroup of patients with non- adenomatous-dominant BPH while they may inspire new options and novel techniques for both BPH treatment and treatment-follow up.

New Sources for Janáček´s Essay Brezovská píseň and His Notation of Long-Drawn-Out Folksongs

Czech Academy of Sciences Publication Activity Database

Procházková, Jarmila

2018-01-01

Roč. 55, č. 1 (2018), s. 41-55 ISSN 0018-7003 Institutional support: RVO:68378076 Keywords : Leoš Janáček (1854-1928) * folklore studies * Janáček´s literary work * Janáček´s collection of folk music Subject RIV: AL - Art, Architecture, Cultural Heritage OBOR OECD: Folklore studies

Reformator Jan Hus - Rezeption seines Lebens und Werks in der modernen Zeit

Czech Academy of Sciences Publication Activity Database

Šebek, Jaroslav

2017-01-01

Roč. 31, č. 59 (2017), s. 19-24 ISSN 0936-7454 Institutional support: RVO:67985963 Keywords : Jan Hus * Modern History * church history Subject RIV: AB - History OBOR OECD: History (history of science and technology to be 6.3, history of specific sciences to be under the respective headings)

Jan Hus v proměnách šesti století

Czech Academy of Sciences Publication Activity Database

Čornej, Petr

2015-01-01

Roč. 17, č. 4 (2015), s. 19-35 ISSN 1212-8570 R&D Projects: GA ČR(CZ) GBP405/12/G148 Institutional support: RVO:68378092 Keywords : Jan Hus * Hussitism * historical tradition * František Palacký * Czech Lands * Catholic church * communist concept Subject RIV: AB - History

Playtechi büroo = Offices of Playtech / Jan Skolimowski, Maie Raud ; kommenteerinud Ivo Lasn

Index Scriptorium Estoniae

Skolimowski, Jan, 1977-

2016-01-01

IT-arendusettevõtte Playtech Tallinna osakonna bürooruumid Ülemiste City uues hoones Lõõtsa tn. 5. Arhitektid Jan Skolimowski, Maie Raud (KAMP Arhitektid). Logo ja viidagraafika Martin Eelma (Tuumik)

Jan Fabre: death and rebirth of the theater

Directory of Open Access Journals (Sweden)

Roberto Giambrone

2012-11-01

Full Text Available Jan Fabre is one of the most controversial European scene figures. His interests range from visual arts to theater and dance. His works, disturbing and provocative, are very contemporary in style and language, while referring to the tradition of Flemish painting. With his performances Fabre demolishes traditional theatre conventions. Theatrical device questioning leads him to disorganize dynamics of representation and to elaborate the concept of crisis until death and apocalypse boundaries. In representing death, Fabre revives theater, according to the principle of metamorphosis. His entire choreography can be defined by balance seeking between opposite poles, good and evil, stasis and movement, beauty and chaos, life and death.

In memory of Professor Jan Mazurkiewicz in the 70th anniversary of his death

Directory of Open Access Journals (Sweden)

Perzyńska-Starkiewicz Aneta

2017-12-01

Full Text Available This article reminisces about the life and career of Jan Mazurkiewicz, one of the most outstanding Polish psychiatrists – the author of Psychophysiological Theory, an original conception of mental disease based on the theory of evolution and dissolution of the nervous system developed by the Englishneurologist John Hughlings Jackson. Professor Jan Mazurkiewicz was an active organizer of psychiatric care. He was co-founder and director of hospitals in Kochanówka and Kobierzyn. He held the rank of Associate Professor at the John Casimir University in Lviv and the position of Professor at the Jagiellonian University in Cracow. From 1919 until his death in 1947, Professor Jan Mazurkiewicz was the head of the Department of Psychiatry at the University of Warsaw. For twenty three years, starting from 1924, he was the president of the Polish Psychiatric Association. The Mazurkiewicz's Psychopathological Theory provides a natural model of development of the highest psychic functions. Damage to a higher evolutionary level of the nervous system leads to the activation of the previously suppressed lower levels, transformed by the pathogen into psychopathological symptoms. Mazurkiewicz's scientific thought was adopted and developed by his student andthen, collaborator, Professor Mieczysław Kaczyński, who was later to become the head of the Department of Psychiatry in Lublin. This work discusses the research conducted at Lublin's Department of Psychiatry which expands on Mazurkiewicz's theory

Zvětšeniny z metody Jaroslavy Janáčkové

Czech Academy of Sciences Publication Activity Database

Jedličková, Alice; Fedrová, Stanislava

2015-01-01

Roč. 63, č. 5 (2015), s. 746-762 ISSN 0009-0468 Institutional support: RVO:68378068 Keywords : Janáčková, Jaroslava * literary theory * literary history * genetic transformational poetics * theory of communication * reception aesthetics * narrative theory Subject RIV: AJ - Letters, Mass-media, Audiovision

Delayed convergence between brain network structure and function in rolandic epilepsy

Directory of Open Access Journals (Sweden)

Rene MH Besseling

2014-09-01

Full Text Available Introduction Rolandic epilepsy (RE manifests during a critical phase of brain development, and has been associated with language impairments. Concordant abnormalities in structural and functional connectivity (SC and FC have been described before. As SC and FC are under mutual influence, the current study investigates abnormalities in the SC-FC synergy in RE. Methods Twenty-two children with RE (age, mean±SD: 11.3±2.0 y and 22 healthy controls (age 10.5±1.6 y underwent structural, diffusion weighted, and functional MRI at 3T. The probabilistic anatomical landmarks atlas was used to parcellate the (subcortical gray matter. Constrained spherical deconvolution tractography and correlation of time series were used to assess SC and FC, respectively. The SC-FC correlation was assessed as a function of age for the non-zero structural connections over a range of sparsity values (0.01-0.75. A modularity analysis was performed on the mean SC network of the controls to localize potential global effects to subnetworks. SC and FC were also assessed separately using graph analysis.Results The SC-FC correlation was significantly reduced in children with RE compared to healthy controls, especially for the youngest participants. This effect was most pronounced in a left and a right centro-temporal network, as well as in a medial parietal network. Graph analysis revealed no prominent abnormalities in SC or FC network organization.Conclusion Since SC and FC converge during normal maturation, our finding of reduced SC-FC correlation illustrates impaired synergy between brain structure and function. More specifically, since this effect was most pronounced in the youngest participants, RE may represent a developmental disorder of delayed brain network maturation. The observed effects seem especially attributable to medial parietal connections, which forms an intermediate between bilateral centro-temporal modules of epileptiform activity, and bear relevance for

Suita a Idylla Leoše Janáčka: jejich recepce a programnost

Czech Academy of Sciences Publication Activity Database

Zapletal, Miloš

2017-01-01

Roč. 55, č. 1 (2017), s. 57-77 ISSN 0018-7003 Institutional support: RVO:68378076 Keywords : Janáček * Suite * Idyll * programme music * music al hermeneutics * absolute music Subject RIV: AL - Art, Architecture, Cultural Heritage

Tim, Jan Lucas ja Karl Robert - vennad üheks kuuks / Maris Laurits

Index Scriptorium Estoniae

Laurits, Maris

2009-01-01

Rakvere Teatri suvelavastuse "Vennad Lõvisüdamed" kaks Karli osatäitjat Jan Lucas Videvik ja Tim Leesnurm ning Joonatani osatäitja Karl Robert Saaremäe tegid Loksal Kaldmaa talus ratsasõiduproove. Üllar Saaremäe lavastuse "Vennad Lõvisüdamed" (Astrid Lindgreni samanimelise jutustuse järgi) esietendus on 11. juunil Rakvere teatri taga aias

Estudio de situación y Plan de Mercadeo para la introducción de la Pastilla Anticonceptiva de Emergencia (PAE), en Costa Rica

OpenAIRE

Carvajal Rojas, Lucrecia

2004-01-01

Universidad de Costa Rica. Posgrado en Administración y Dirección de Empresas. Maestría Profesional en Administración y Dirección de Empresas con énfasis en Mercadeo y Ventas El objetivo general del trabajo es investigar la situación actual y los distintos públicos de la PAE en Costa Rica, para desarrollar un plan de mercadotecnia, que le garantice a la Asociación Demográfica Costarricense el éxito en la introducción, educación y divulgación de este método anticonceptivo de emerge...

Apollo külastajate lemmikuks on Jan Kausi ja David Mitchelli raamatud / Jaak Urmet

Index Scriptorium Estoniae

Urmet, Jaak, 1979-

2006-01-01

Apollo kaupluse koduleheküljel valiti parimaks ilukirjandusteoseks Jan Kausi "Tema", tõlgitud ilukirjanduse osas David Mitchelli "Pilveatlas", luuleraamatutest Ott Arderi "Luule sünnib kus sünnib kui sünnib" ja lasteraamatutest Christopher Paolini "Vanem"

Apoteóza Sokola, armády a nového člověka: rané recepce Janáčkovy Sinfonietty

Czech Academy of Sciences Publication Activity Database

Zapletal, Miloš

2016-01-01

Roč. 53, 2/3 (2016), s. 257-287 ISSN 0018-7003 Institutional support: RVO:68378076 Keywords : Leoš Janáček * Sinfonietta * reception of music * Janáček reception * reception studies Subject RIV: AL - Art, Architecture, Cultural Heritage

Jan Lever: Challenging the Role of Typological Thinking in Reformational Views of Biology

NARCIS (Netherlands)

Cook, Harry; Flipse, A.C.

2017-01-01

This essay analyzes the view of evolution of Jan Lever (1922–2010), founder of the biology department at the Vrije Universiteit Amsterdam, and compares his view with those of J.H. Diemer and H. Dooyeweerd. Together with Dooyeweerd, Lever wrote a series of chapters on the species concept in

Jan Baudouin de Courtenay’s concept of mixed languages

Directory of Open Access Journals (Sweden)

Rado L. Lencek

1978-12-01

Full Text Available This paper addresses the problem of defining the notion of mixture in languages and dialects as used by Jan Baudouin de Courtenay (1845 - 1929. Focussing on the types of interference which were formulated on the basis of observations of the dialects of the Slovene language (5 , the paper deals primarily with those Baudouin's theoretical positions (4, observations and deductions (5.1 which are today part of a theory of linguistic interference. The article is an English version of a paper, presented at the Eighth International Congress of Slavists which was held in Zagreb from the 3rd to the 9th September 1978.

Ostame maja! / Kersti Pikk, Aet Piel, Piret Tali

Index Scriptorium Estoniae

Pikk, Kersti

2007-01-01

Võrreldakse kolme eramut - Pirital, Viimsis (Arhitektuuriagentuur OÜ - arhitektid Inga Raukas, Toomas Tammis, Karli Luik ja Renee Puusepp) ja Harku vallas Vatslas. Lk. Oberhausi kinnisvaraspetsialisti Ene Arro kommentaar

Tantrums, Emotion Reactions and Their EEG Correlates in Childhood Benign Rolandic Epilepsy vs. Complex Partial Seizures: Exploratory Observations.

Science.gov (United States)

Potegal, Michael; Drewel, Elena H; MacDonald, John T

2018-01-01

We explored associations between EEG pathophysiology and emotional/behavioral (E/B) problems of children with two types of epilepsy using standard parent questionnaires and two new indicators: tantrums recorded by parents at home and brief, emotion-eliciting situations in the laboratory. Children with Benign Rolandic epilepsy (BRE, N = 6) reportedly had shorter, more angry tantrums from which they recovered quickly. Children with Complex Partial Seizures (CPS, N = 13) had longer, sadder tantrums often followed by bad moods. More generally, BRE correlated with anger and aggression; CPS with sadness and withdrawal. Scores of a composite group of siblings ( N = 11) were generally intermediate between the BRE and CPS groups. Across all children, high voltage theta and/or interictal epileptiform discharges (IEDs) correlated with negative emotional reactions. Such EEG abnormalities in left hemisphere correlated with greater social fear, right hemisphere EEG abnormalities with greater anger. Right hemisphere localization in CPS was also associated with parent-reported problems at home. If epilepsy alters neural circuitry thereby increasing negative emotions, additional assessment of anti-epileptic drug treatment of epilepsy-related E/B problems would be warranted.

Jan Baptist Xavery (1697-1742: A versatile garden artist

Directory of Open Access Journals (Sweden)

Dennis de Kool

2011-04-01

Full Text Available Dutch garden sculpture from the 18 th century is worthy of more systematic study. Such research may offer valuable insights into the position of garden sculpture within sculpture proper and its meaning in 18 th-century garden art. Jan Baptist Xavery is regarded as one of the most important sculptors working in the Netherlands during the 18 th century. His artistic career, his versatile body of work and his influence on other artists should therefore be studied in more depth. In view of the bloom in garden art in those days Xavery's significance as a 'garden artist' should not be overlooked in such a study. Garden sculptures should not be regarded as independent objects or pure decorative elements, but must be considered within the wider context of garden history. Tragically, many garden ornaments have been removed from their natural green environment. In their new settings they sometimes acquire a new meaning, but more often than not they are not done justice as the original harmonious 'composition' has been lost. As a result, this cultural-historical heritage is often treated indifferently. The few garden sculptures that have survived all calamities and can still be admired in public places are often placed at unsuitable locations and suffer from the weather or vandalism. Many garden sculptures, often damaged, have ended up anonymously in museum depots. Although they are safe there, the dreary catacombs of museums are a far cry from the green surroundings for which they were originally intended. Garden ornaments were, after all, not made for depots but to be looked at, studied and admired by enthusiasts, preferably in green surroundings. Otherwise, they will literally disappear from collective memory. Surely, the talented Jan Baptist Xavery and his contemporaries deserve a better fate than that.

Reconsidering the Roland-Morris Disability Questionnaire: time for a multidimensional framework?

Science.gov (United States)

Magnussen, Liv Heide; Lygren, Hildegunn; Strand, Liv Inger; Hagen, Eli Molde; Breivik, Kyrre

2015-02-15

Cross-sectional design. To explore (1) the factor structure of the Roland-Morris Disability Questionnaire (RMDQ), (2) whether there is a dominant factor, and (3) whether the potential factors are unique predictors of other aspects related to back pain. The RMDQ is one of the most recommended back-specific questionnaires assessing disability. The RMDQ is scored as a unidimensional scale summarizing answers to all 24 questions (Yes/No) regarding daily life functioning. However, there are indications that the scale is multidimensional. Patients (n = 457; age, 18-60 yr) with 8 to 12 weeks of back pain filled in questionnaires assessing subjective health complaints, emotional distress, instrumental and emotion-focused coping, and fear voidance behavior at baseline. A total of 371 patients (81.7%) filled in the RMDQ. Exploratory factor analysis was used to examine the factor structure of RMDQ items. Multiple regression analyses were used to assess whether the derived factors predicted relevant problems in back pain differently. Exploratory factor analysis showed indices of model fit for a 3-factor solution after removing 2 items because of low prevalence (19 and 24). Two items were removed because of cross-loadings and low loadings (2 and 22). No support for a dominant factor was found as the 3 factors were only moderately correlated (r = 0.34-0.40), and the ratio between the first and second eigenvalue was 2.6, not supporting essential unidimensionality. "Symptoms" were the factor that most strongly predicted subjective health complaints, whereas "avoidance of activity and participation" predicted fear avoidance behavior, instrumental and emotional coping. "Limitation in daily activities" did not predict any of these variables. The main findings of our study are that the RMDQ consists of 3 independent factors, and not 1 dominant factor as suggested previously. We think the time is now ripe to start treating and scoring the RMDQ as a multidimensional scale. N/A.

Jan Novák, žák Bohuslava Martinů

OpenAIRE

Flašar, Martin

2006-01-01

When comparing the fate of Bohuslav Martinů to that of his pupil Jan Novák, interesting parallels can be found, not only in their work (with which this article does not deal), but also in their lives. Both composers met in 1947 in the U.S.A., and, for half a year, they worked together in New York. Novák’s 1950s compositions were strongly influenced by Martinů’s style. At the same time, both of them suffered the disgrace of the Czechoslovak cultural politics and its executors. Novák venerated ...

Strontium-90 and cesium-137 in rice (consuming districts) (from Nov. 1982 to Jan. 1983)

International Nuclear Information System (INIS)

1983-01-01

Strontium-90 and cesium-137 in rice (consuming districts from Nov. 1982 to Jan. 1983) were determined. Polished rice was collected in eight consuming areas when new crops were first put on sale. The results are shown in a table. (J.P.N.)

CWEesti / Inga Raukas

Index Scriptorium Estoniae

Raukas, Inga, 1967-

1998-01-01

Coast Wise Europe (CWE) konteinernäitus 1.-19. aprillini Eesti Arhitektuurimuuseumis. Konteiner sisaldas tuhandete arhitektuuriüliõpilaste töid rannikute teemadel. Eesti projektis osales üle 30 Eesti Kunstiakadeemia üliõpilase ja magistrandi. Rahvusvahelisest arhitektuurikoolide koostööprojektist CWE, mille üks peateema on arhitektuuri seisukohalt turismi fenomeni uurimine ja rannikute kaardistamine. CWE Eesti näitusest, konverentsist, Eesti atlasest, tagasivaade nelja aasta jooksul toimunule.

Nicolas Lyon-Caen , La boîte à Perrette, le jansénisme parisien au xviiie siècle

OpenAIRE

Vermander, Benoît

2012-01-01

Nicolas Lyon-­­­Caen publie ici sa thèse sou­­te­­nue en 2008 à l’uni­­ver­­sité Paris I (dir. Cl. Mi­­­chaud) sous le titre Mar­­chands de miracles. La bour­­geoi­­sie jan­­sé­­niste pari­­sienne au xviiie siècle, elle-­­­même pro­­lon­­ge­­ment d’une thèse de l’École des Chartes consa­­crée au finan­­ce­­ment du « parti » jan­­sé­­niste au xviiie siècle (La boîte à Perrette, 2002). Ce n’est donc pas une his­­toire de l’ensemble des jan­­sé­­nistes pari­­siens que l’on trou­­vera dans cet ou...

Failing at College Football Reform: The Jan Kemp Trial at the University of Georgia

Science.gov (United States)

Fulford, Michael J.

2008-01-01

Throughout the history of college football, there have been efforts to reform the system and stop improprieties, yet conflict between gaining academic and athletic prowess at colleges remained a central theme. In the 1980s, the Jan Kemp trial involving the University of Georgia demonstrated this clash between revenue-generating athletics and…

Source study of the Jan Mayen transform fault strike-slip earthquakes

Science.gov (United States)

Rodríguez-Pérez, Q.; Ottemöller, L.

2014-07-01

Seismic source parameters of oceanic transform zone earthquakes have been relatively poorly studied. Previous studies showed that this type of earthquakes has unique characteristics such as not only the relatively common occurrence of slow events with weak seismic radiation at high frequencies but also the occurrence of some events that have high apparent stress indicating strong high frequency radiation. We studied 5 strike-slip earthquakes in the Jan Mayen fracture zone with magnitudes in the range of 5.9 centroid time delay compared to other oceanic transform fault earthquakes.

"Курорт закончился". Глобальный экономический кризис и архитекторы Балтии. Круглый стол = "The holiday is over". The global financial crisis and Baltic architects. Round table

Index Scriptorium Estoniae

2008-01-01

Globaalse majanduslanguse mõjust arhitektuuribüroode tööle. Büroode tegevusstrateegiast kriisi ajal. Vestlusringis osalesid eestlastest Inga Raukas (Arhitektuuriagentuur) ja Mattias Agabus (Agabus, Endjärv & Truverk Arhitektid)

Possible future petroleum activity around Jan Mayen. Consequences of emissions to air.; Aapning av havomraadene ved Jan Mayen for petroleumsvirksomhet. Konsekvenser av regulaere utslipp til luft.

Energy Technology Data Exchange (ETDEWEB)

Solberg, Sverre; Svendby, Tove; Gjerstad, Karl Idar; Liu, Li; Wathne, Bente M.; Skjelkvaale, Brit Lisa; Hoegaasen, Tore; Aarrestad, Per Arild; Gjershaug, Jan Ove

2012-07-01

Norwegian Institute for Air Research (NILU), Norwegian Institute for Water Research (NIVA) and the Norwegian Institute for Nature Research (NINA) have considered the effects on the environment of emissions of NO{sub x}, SO{sub 2} and particulate matter into the air from any future petroleum activity in the waters around Jan Mayen. It is estimated deposition of nitrogen, sulfur and particulates - also formation of ozone is calculated. It is also considered what effect it has on nature. Calculations indicate that emissions most likely will not lead to negative effects on vegetation and fauna of the terrestrial impact area. (Author)

Mr. Jan Hendrik Bannier and Dr. Gosta Funke

CERN Document Server

CERN PhotoLab

1966-01-01

(on the left) : Mr. Jan Hendrik Bannier has been President of the Council at CERN for the years 1964, 1965 and 1966 and was President of the Finance Committee from 1958 to 1960. He is now a member of the Site Evaluation Panel for the 300 GeV accelerator project. In the Netherlands, he is Director of ZWO (Organization for the Advancement of Pure Research) and also Vice-President of the National Commission for UNESCO. (on the right) : Dr. Gosta Funke, who has represented his country at CERN Council sessions since the beginning of the Organization, was elected President of the Council for 1967 at its Thirty-third Session, in December. In Sweden, he has been Secretary-General of the State Council for Atomic Research since 1959. He is also President of the Council of ESO (European Southern Observatory), an organization building in Chili.

Tantrums, Emotion Reactions and Their EEG Correlates in Childhood Benign Rolandic Epilepsy vs. Complex Partial Seizures: Exploratory Observations

Directory of Open Access Journals (Sweden)

Michael Potegal

2018-03-01

Full Text Available We explored associations between EEG pathophysiology and emotional/behavioral (E/B problems of children with two types of epilepsy using standard parent questionnaires and two new indicators: tantrums recorded by parents at home and brief, emotion-eliciting situations in the laboratory. Children with Benign Rolandic epilepsy (BRE, N = 6 reportedly had shorter, more angry tantrums from which they recovered quickly. Children with Complex Partial Seizures (CPS, N = 13 had longer, sadder tantrums often followed by bad moods. More generally, BRE correlated with anger and aggression; CPS with sadness and withdrawal. Scores of a composite group of siblings (N = 11 were generally intermediate between the BRE and CPS groups. Across all children, high voltage theta and/or interictal epileptiform discharges (IEDs correlated with negative emotional reactions. Such EEG abnormalities in left hemisphere correlated with greater social fear, right hemisphere EEG abnormalities with greater anger. Right hemisphere localization in CPS was also associated with parent-reported problems at home. If epilepsy alters neural circuitry thereby increasing negative emotions, additional assessment of anti-epileptic drug treatment of epilepsy-related E/B problems would be warranted.

Constraining formation of the Eggvin Bank (West of Jan Mayen, N. Atlantic) from OBS data

Science.gov (United States)

Tan, P.; Breivik, A. J.; Mjelde, R.; Azuma, R.

2015-12-01

The anomalously high magma flux in the Eggvin Bank area has triggered new research efforts to better understand the crustal development in this area. The Eggvin Bank is located between the Jan Mayen Island and the west coast of Greenland. Some proposed origins of the Eggvin Bank are: a distinct plume located beneath Jan Mayen; an extension of the Iceland plume; minor spreading or leakage along West Jan Mayen Fracture Zone (WJMFZ); intruded continental crust extending from Jan Mayen Microcontinent (JMMC); and rifted Greenland sub-continental lithospheric mantle. In this first modern refraction seismic study of the Eggvin Bank, we present a 2D velocity model based on OBS data. The OBSs were deployed approx. N-S over the Eggvin Bank with good data quality constrained by 4 OBSs. The air-gun array used during OBS shooting produced good quality reflection data. Three distinct seamounts are observed along the profile: the northern seamount (water depth 730m), has a flat top with a thin sedimentary veneer on top, which indicates it has been eroded at sea surface; while the southern two seamounts, one (water depth 550m) is less flat with around 100m thick sedimentary units on top, another one is rounded with tiny sedimentary veneer on top having the shallowest water depth (460m). This could suggest that the southern seamounts are younger, since they are shallower but without obvious signs that they were subaerially exposed. However, increased cooling of the lithosphere across the WJMFZ in the north may also contribute to depth differences. A normal fault offsetting sedimentary strata (~300 m) in the Greenland Basin indicates recent tectonic activity north of the Eggvin Bank. The velocity modeling shows crustal thickness with large variations, ranging from 8 km to 14 km, where crustal thickness changes of 4-5 km are associated with 20-30 km wide segments with thick crust under the seamounts. The crust consists of three oceanic crustal layers: upper crust (2.8km/s-4.8km

Janáčkovy srbské foklorní inspirace: Zpěvy lidu srbského

Czech Academy of Sciences Publication Activity Database

Procházková, Jarmila

2011-01-01

Roč. 48, č. 4 (2011), 393-402 ISSN 0018-7003 R&D Projects: GA ČR GA408/08/1330 Institutional research plan: CEZ:AV0Z90580513 Keywords : Leoš Janáček Subject RIV: AC - Archeology, Anthropology, Ethnology

Heiastusi perifeeriast : ühe rändnäituse kiiluvees / Rait Parts, Merle Kasonen, Jan Skolimowski

Index Scriptorium Estoniae

Parts, Rait, 1980-

2014-01-01

Kultuuri ja looduse piirimaadest, perifeeria tundmisest ja selle omaks pidamisest. Merle Kasoneni ja Jan Skolimowski lõigud ehtekunsti näitusest "Ümber nurga" Hobusepea 2 sisehoovis 8. - 22. märts 2014 ja Soomaal, Mardu talus 31.05 - 27.07.2014

JAN DUIKER: A RIVER SIDE HOTEL IN DOLNÍ ZÁLEZLY NAD LABEM, CZECH REPUBLIC 1929-1930 / Jan Duiker: un hotel junto al río en Dolní Zálezly nad Labem,República Checa 1929-1930

Directory of Open Access Journals (Sweden)

Jan Molema

2014-05-01

Full Text Available SUMMARY After the early death of Jan Duiker, his compatriot Han van Loghem wrote: “By no means everything in Duiker is sound in the sense of the mathematical technique, and often not from the viewpoint of centuries long utility. But precisely this makes that his work contains the freshness of the continuously renewing nature.” (De Hollandsche revue, jrg 41, 1936, no 8, p. 366. Van Loghem’s book Bouwen Bauen Building Batîr (1932 has been the only publication in Duiker’s life time in which some space was dedicated to his highly interesting entry for a competition for a riverside hotel in Salesel an der Elbe, now (Dolní Zálezly nad Labem in the Czech Republic. In this article the writer has tried to understand the project with his knowledge of Jan Duiker’s work in general, from what Van Loghem published, and some additional drawings discovered and published in later years. Duiker’s archive contains nothing. A detective story. RESUMEN Después de la temprana muerte de Jan Duiker, su compatriota Han van Loghem escribió: “De ninguna manera en Duiker todo es inalterable en el sentido técnico de las matemáticas, y sobre todo desde el punto de vista de la utilidad a lo largo de los siglos. Pero precisamente esto hace que su trabajo contenga la frescura de la naturaleza que continuamente se renueva” (De Hollandsche revue, jrg 41, 1936, no 8, p. 366. El libro de Van Loghem Bouwen Bauen Building Batîr (1932 ha sido la única publicación sobre Duiker en vida en el cual, algunas partes, estaban dedicadas a su interesantísimo proyecto para el concurso para un hotel junto al río en Salesel an der Elbe, ahora (Dolní Zálezly nad Labem en la República Checa. En este artículo, he intentado entender el proyecto con el conocimiento que tengo, en general, del trabajo de Jan Duiker, con lo publicado por Van Loghem y algunos dibujos adicionales descubiertos y publicados años más tarde. En el archivo de Duiker no hay nada. Ha sido una

The Persistence of Utopia: Plasticity and Difference from Roland Barthes to Catherine Malabou

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Jennifer A. Wagner-Lawlor

2017-12-01

Full Text Available The theorizing of utopia is a persistent theme throughout several generations of the French continental tradition, and alongside the process theory of Alfred North Whitehead to a large degree recuperates the concept of utopia from its supposed dismissal by Marx and his intellectual descendants. Most recently, attention to the notion of plasticity, popularized (relatively speaking by Catherine Malabou, extends speculation on utopian possibility.  Compelled to answer to Marx’s denigration of utopia as fantasy, the tendency was (still is, for many to compensate for the absence of a programmatic politics by stressing what is “useful” about utopian dreaming, and therefore where or how exactly a utopian text reveals or creates political drive, or motivates political action. In this essay, I argue that theorists have overlooked the use of utopia as not only the reproduction of difference, or what Malabou calls positive plasticity, but also as, therefore, a disruption; Malabou might prefer the term accident here. Tracing the concept of plasticity from Roland Barthes to Malabou, with a nod at Miguel Abensour, this essay teases out the links between a contemporary notion of plasticity to argue, simply put, that utopia is plastic. This plasticity of the concept ensures its political force. These links, obscured in the essay “Plastic,” Barthes makes only later in his writing. But for Malabou, plasticity underlies a principle of futurity and/as generativity, such that new forms, new meanings, new concepts emerge through difference. Utopia’s horizons of potentiality depend on difference, and on non-achievement. Finally, I argue that the persistence of utopia (Abensour as a form of thinking is the most important, and political, effect of utopian plasticity.

Geology and assessment of undiscovered oil and gas resources of the Jan Mayen Microcontinent Province, 2008

Science.gov (United States)

Moore, Thomas E.; Pitman, Janet K.; Moore, Thomas E.; Gautier, D.L.

2018-01-26

The Jan Mayen Microcontinent encompasses a rectangular, mostly submarine fragment of continental crust that lies north of Iceland in the middle of the North Atlantic Ocean. These continental rocks were rifted away from the eastern margin of Greenland as a consequence of a westward jump of spreading centers from the now-extinct Aegir Ridge to the currently active Kolbeinsey Ridge in the Oligocene and early Miocene. The microcontinent is composed of the high-standing Jan Mayen Ridge and a series of smaller ridges that diminish southward in elevation and includes several deep basins that are underlain by strongly attenuated continental crust. The geology of this area is known principally from a loose collection of seismic reflection and refraction lines and several deep-sea scientific drill cores.The Jan Mayen Microcontinent petroleum province encompasses the entire area of the microcontinent and was defined as a single assessment unit (AU). Although its geology is poorly known, the microcontinent is thought to consist of late Paleozoic and Mesozoic rift basin stratigraphic sequences similar to those of the highly prospective Norwegian, North Sea, and Greenland continental margins. The prospectivity of the AU may be greatly diminished, however, by pervasive extensional deformation, basaltic magmatism, and exhumation that accompanied two periods of continental rifting and breakup in the Paleogene and early Neogene. The overall probability of at least one petroleum accumulation of >50 million barrels of oil equivalent was judged to be 5.6 percent. As a consequence of the low level of probability, a quantitative assessment of this AU was not conducted.

Proměny a konstanty Helfertova psaní o Janáčkovi

Czech Academy of Sciences Publication Activity Database

Zapletal, Miloš

2016-01-01

Roč. 51, č. 2 (2016), s. 237-271 ISSN 1212-0391 Institutional support: RVO:68378076 Keywords : Helfert * Janáček * reception of music * discourse analysis * music criticism * methodologies of musical historiography * conceptions of history * writing (écriture) Subject RIV: AL - Art, Architecture, Cultural Heritage OBOR OECD: Performing arts studies (Musicology, Theater science, Dramaturgy) https://digilib.phil.muni.cz/bitstream/handle/11222.digilib/136152/1_MusicologicaBrunensia_51-2016-2_22.pdf?sequence=1

Eavesdropping with a Master: Leoš Janáček and the Music of Speech

Directory of Open Access Journals (Sweden)

Jonathan Pearl

2006-07-01

Full Text Available The composer Leos Janácek (1854-1928 has been noted for his interest in speech melodies. Little discussion has focused however on the field methods that he used in gathering them, nor on the products themselves. Janácek spent more than three decades, transcribing thousands of what he termed nápevky mluvy [tunelets of speech] in standard musical notation. The record that remains of these efforts is impressive both for its volume and its quality, as well as for its potential to reveal aspects of the perceptual overlap between music and language. Heretofore his pioneering efforts in the study of speech prosody and music perception have neither been recognized nor acknowledged. The present study provides a background for and an overview of the transcriptions, along with comparative musicological and linguistic analyses of the materials presented. With this analysis as a starting point, I indicate promising avenues for further collaborations between linguists and musicologists, seeking an integrated theory of music and language cognition.

Comet Kohoutek, The Arab Oil Embargo, and the Jan 1974 AAS Meeting

Science.gov (United States)

Duncan, D. K.

1999-05-01

An unlikely combination of factors, including Comet Kohoutek and the Arab Oil embargo, combined to make my first AAS Meeting my most memorable. Three young graduate students confronted lack of gas, lack of money, and lack of planning to attend the Jan 1974 meeting in Tucson, AZ. One, Steve Hawley, displayed skills which would later be valuable when he became the astronaut who launched HST. Although we became stranded in the desert, two of the three of us made it to the meeting, and only one didn't....

Religion, symbols and the human condition : An analysis of the basic ideas of Jan van Baal

NARCIS (Netherlands)

Kuiper, Yme; Hubbeling, Hubertus G.; Kippenberg, Hans G.

1986-01-01

The anthrology of religion of the eminent Dutch scholar Jan van Baal is a lucid synthesis of existentialm and structuralism. Van Baal interprets religion and ritual as symbols for communication. His fieldwork among the Marind-anim in Dutch New Guinea has strongly been inspired by Dutch and French

L’Arioste et l’Empire. Réflexions sur les rédactions du Roland furieux

Directory of Open Access Journals (Sweden)

Giuseppe Sangirardi

2012-06-01

Full Text Available Révisant la thèse communément admise de la « dimension impériale » de la troisième rédaction du Roland furieux (1532, l’article montre l’ambiguïté de l’éloge que l’Arioste adresse à Charles-Quint, à partir des faiblesses de l’image de Charlemagne et de l’importance donnée à des personnes tel qu’Andrea Doria. La reprise de l’esthétique des poètes de l’âge d’Auguste n’est pas l’effet de la geste impériale mais reprend les développements de la poésie à la cour de Ferrare, lieu de l’élaboration d’un canon de la poésie de goût classique.Revisando la tesis comúnmente admitida de la «dimensión imperial» de la tercera redacción del Orlando furioso (1532, este artículo muestra la ambigüedad del elogio que Ariosto dirige a Carlos V, a partir del carácter débil y vacilante de la figura de Carlomagno y de la importancia dada a personas como Andrea Doria. La recuperación de la estética de poetas de la edad de Augusto no es el efecto de la gesta imperial, sino que retoma temas ya anteriormente desarrollados por la poesía de la corte de Ferrara, en cuyo seno se elabora un canon de la poesía clasicista.

Nocturnus Muhumaal

Index Scriptorium Estoniae

2001-01-01

7.-16. IX Pädaste mõisahoones rahvusvaheline ehtekunstinäitus "Nocturnus", kuhu kunstnikud valis Kadri Mälk. Kujundaja Inga Raukas. Nimekamad osalejad: Manfred Bischoff, Mari Funaki, Giovanni Corvaja, Bettina Speckner, Esther Brinkmann, Xavier Domenech. Kollokviumil esinejad.

Analysis of PAEs contaminants in water sources for agriculture, industrial and residential areas from local city district

Science.gov (United States)

Chen, Qidan; Chen, Qixian; Wu, Fei; Liao, Jia; Zhao, Xi

2018-02-01

The technology of DEHP and DBP detection by high performance liquid chromatography coupled with ultraviolet detection (HPLC-UV) was developed and applied in analysis of local water sources from agriculture, industrial and residential areas. Under the optimized sample pretreatment and detection conditions, DEHP and DBP were well separated and detected in 4 mins. The detection limit of DBP was 0.002 mg/L and DEHP was 0.006 mg/L, and it meets the Chinese National Standard limitations for drinking water quality. The linear correlation coefficient of DBP and DEHP standard calibration curves was 0.9998 and 0.9995. The linear range of DBP was 0.020 mg/L ∼20.0 mg/L, with the standard deviation of 0.560% ∼5.07%, and the linear range of DEHP was 0.060 mg/L ∼15.0 mg/L, with the standard deviation of 0.546% ∼5.74%. Ten water samples from Jinwan district of Zhuhai in Guangdong province of China were analyzed. However, the PAEs amounts found in the water sources from industrial areas were higher than the agriculture and residential areas, industries grow incredibly fast in the district in recently years and more attention should be paid to the increasing risks of water sources pollution.

The psychometric properties of the Roland Morris disability questionnaire for patients with chronic mechanical low back pain

Directory of Open Access Journals (Sweden)

H. Buchanan

2007-01-01

used in South Africa to facilitate clinical decision-making or document treatment outcomes for patients with low back pain (LBP. This study investigated the internal consistency and clinical utility of a back-specific functional status measure, the Roland Morris Disability Questionnaire (RMDQ, and determined its ability to confirm the need for spinal fusion surgery. Method: Aretrospective, descriptive design was used with 42 patients with chronic mechanical low back pain who consulted a private Orthopaedic surgeon in Cape Town over a one year  period. All patients completed the RMDQ prior to their consultation. On completion of the medical examination, a rating for surgery was determined for each patient. The completed questionnaires were analysed using Statistical Package for the Social Sciences (SPSS. Results: The mean RMDQ score was 8.6 (N=42; median=9.0; range=2-21. Cronbach’s alpha showed a high internal consistency between items (.92. A categorical principal component analysis (CATPCA identified two distinct dimensions in the RMDQ. Item reduction improved the internal consistency and thus the construct validity of the RMDQ. There was a low correlation between the surgeon’s rating for surgery and RMDQ scores (r=.40; P<.01. Conclusion: The RMDQ shows some good psychometric properties but some adjustments could improve it. The RMDQ cannot be used to predict the need for spinal fusion surgery.

The genesis of Jan Steens painting 'As the old ones sing, so the young ones pipe' from the Gemaeldegalerie Berlin

International Nuclear Information System (INIS)

Denker, A.; Kleinert, K.; Laurenze-Landsberg, C.; Reimelt, M.; Schroeder-Smeibidl, B.

2011-01-01

In collaboration with the research reactor of the Helmholtz-Zentrum Berlin fuer Materialien und Energie, the Gemaeldegalerie Berlin is the only institute worldwide, which systematically employs the method of Neutron-Activation-Autoradiography to analyze paintings and painting techniques. To date more than 70 paintings were investigated with this effective, non-destructive, and exceptional method. It allows the visualization of structures and layers beneath the top surface and, in addition, enables the identification of elements contained in the pigments. The instrument B8 at the research reactor BER II is dedicated to this research. Jan Steen is one of the prolific artists from the 17th century. Like other artists from that time he produced several versions of one specific topic during life-time. The topic 'As the old ones sing, so the young ones pipe' was painted by Jan Steen in 13 versions. The painting from the Gemaeldegalerie is an exception in this series as it differs in style and content from the other oeuvres. The question arises: why did the artist deviate from his usual scheme? The possible answer is provided by X-ray images and neutron autoradiographs made of the painting, allowing insight into hidden paint layers and, therefore, in the genesis of the painting. Jan Steen did not simply change the composition of the room and the figures. He originally intended an altogether different topic. Assumedly it was supposed to be a so-called merry company, located in a generous, stately room. Many pieces of this sophisticated ambiance have been eliminated from the version visible today; others were modified and integrated into the composition of the new painting. Thus, Jan Steen commenced the topic 'As the old ones sing, so the young ones pipe' from a different context.

Jan Patočka’s Concept of Fraternity and its Challenges vis-à-vis the World of Today

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Zuzana Svobodová

2017-12-01

Full Text Available The presentation entitled “Jan Patočka’s Concept of Fraternity and its Challenges vis-à-vis the World of Today” discusses the concept of fraternity explored in texts by the Czech philosopher written later in his life. J. Patočka was one of the authors of Charter 77, a dissident document, which called for the protection of human rights (published on January 6.–7., 1977. First, Patočka’s theory of three movements of life (also: movements of the soul – i.e. the movement of rooting or anchoring, the movement of labour or self-delivery and the movement of breakthrough or finding oneself – will be analysed. Based on the analysis, the role of turning (gr. metanoiésis from a mere solidarity of interests to actual being through surrendering oneself will be shown. Jan Patočka interpreted life as surrender by referring to the notion of Godman and the way the world relates to him. The phenomenon of sacrifice that Jan Patočka dealt with in the last period of his life (Patočka died on March 13, 1977, following long and exhausting police interrogations can inspire the field of social ethics, both from the philosophical and theological points of view. It also comes with challenges to education and training in today’s Europe, which faces migration, as it needs to learn new habits of hospitality and fraternity.  

Une étude de cas. Saint Sébastien dans “Je suis sang” de Jan Fabre

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Lydie Toran

2017-06-01

Full Text Available Jan Fabre’s writing frequently displays a variety of quotations, especially visual ones. His 2001 Je suis sang (conte de fées médiéval is directly and indirectly inspired by Saint Sebastian’s iconography. This study examines the modalities and functions of this re-use in detail.

Silmapaistvaid metsateadlasi Tallinnas 20. sajandi esimesel poolel / Malev Margus

Index Scriptorium Estoniae

Margus, Malev, 1923-2014

1996-01-01

Julius Kitsing; Jaan Hellat; Aleksander Pals; Arnold Merihein; Voldemar Mathiesen; Bernhard Tuskvere; Kaljo Sotter; Vassili Mutt, Jaan Luik; Aleksander Raukas; Valdur Küng; Nikolai Küttis; Viktor Obet; Jakob Visnapuu; Karl Keerdoja; Edgar Vester. Lühiandmeid. Kokkuv. ingl. k.

Ebamäärasus kui eesmärk : "Coast Wise Europe'i" näitus ja konverents Rotermanni soolalaos / Karin Hallas

Index Scriptorium Estoniae

Hallas-Murula, Karin, 1957-

1998-01-01

Aprillis eksponeeritud näitusest "Coast Wise Europe" ja 17. aprillil toimunud konverentsist "Ebamäärasus". David Milleri, Mart Raukase, Kaia Lehari, Inga Raukase, Kaarel Orviku ettekannetest. Ürituse korraldaja ja Eesti-poolse "Coast'i" eestvedaja Inga Raukas.

Jan Vejrych (1856–1926). Život a dílo architekta z Horní Branné u Jilemnice

Czech Academy of Sciences Publication Activity Database

Uhlík, Jan

2016-01-01

Roč. 17, č. 1 (2016), s. 18-37 ISSN 1213-5097 Institutional support: RVO:68378033 Keywords : Jan Vejrych * Horní Branná * history of architecture Subject RIV: AL - Art, Architecture, Cultural Heritage

Hudební stránka Janáčkových folklorních záznamů

Czech Academy of Sciences Publication Activity Database

Procházková, Jarmila

2004-01-01

Roč. 36, č. 6 (2004), s. 20-26 ISSN 0862-8505 Institutional research plan: CEZ:AV0Z9058907 Keywords : folk music * folksong * Leoš Janáček * recordings of folk music Subject RIV: AC - Archeology, Anthropology, Ethnology

Inzicht door onderdompeling Een reactie op Bart Van de Putte, Henk de Smaele en Dirk Jan Wolffram

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Jan Hein Furnée

2014-09-01

Full Text Available Giving a detailed account of the social history of The Hague’s most prominent sites of civilised leisure – the gentlemen’s clubs, the zoo, the Royal Theatre and the seaside resort of Scheveningen – Plaatsen van beschaafd vertier demonstrates how the constant struggle for social in- and exclusion structured the daily lives of upper and middle class men and women in The Hague in the nineteenth century. In response to Bart Van de Putte, Jan Hein Furnée argues that extensive quantitative analyses of ‘class’ and ‘social class’ show that objective class stratifications based onwealth and/or occupation are important tools, but at most semi-finished products for historical research. Furnée fully agrees with Henk de Smaele’s objection that his study would have benefitted from a more in-depth reflection on the ways in which shifting patterns in women’s freedom of movement in urban spaces were related to their political and economic emancipation. In response to Dirk Jan Wolffram, Furnée repeats some examples given in his book that show how political practices in places of leisure impacted upon local and national politics, even though this didnot directly contribute to a linear process of increasing political participation and representation.Aan de hand van een gedetailleerde analyse van de sociale geschiedenis van herenen burgersociëteiten, de dierentuin, de Koninklijke Schouwburg en badplaats Scheveningen demonstreert Plaatsen van beschaafd vertier hoe de constante strijd om sociale in- en uitsluiting het dagelijks leven van mannen en vrouwen uit de hogere en middenstanden in negentiende-eeuws Den Haag beheerste. In reactie op Bart Van de Putte betoogt Jan Hein Furnée dat grondige kwantitatieve analyses van ‘class’ en ‘social class’ uitwijst dat objectieve sociale stratificaties op basis van welstand en/of beroep voor historisch onderzoek weliswaar zeer nuttig enzelfs noodzakelijk, maar uiteindelijk slechts een

Pinnavormimise kunst / Inga Raukas

Index Scriptorium Estoniae

Raukas, Inga, 1967-

2006-01-01

2006. a. Barcelonas Land & Scape'i seerias ilmunud Ilka & Andreas Ruby raamatust maastikulisest arhitektuurist "Groundscapes. The rediscovery of the ground in contemporary arhitecture" (Editorial Gustavo Gili)

Relvastatud bobby / Mart Raukas

Index Scriptorium Estoniae

Raukas, Mart

2005-01-01

Londonis toimunud tragöödiast, kus politseinik tappis metroojaamas terroristiks peetud brasiillase. Autor leiab, et kui kogenematule politseinikule on antud käsk oletatavat terroristi esimesel võimalusel pähe tulistada, tähendab see juba lasku ükskõik kelle suunas

Cross-cultural Adaptation of Roland-Morris Disability Questionnaire Needs to Assess the Measurement Properties: A Systematic Review.

Science.gov (United States)

Yao, Min; Zhu, Sen; Tian, Zi-Rui; Song, Yong-Jia; Yang, Long; Wang, Yong-Jun; Cui, Xue-Jun

2018-03-26

To assess the cross cultural-adaptations of the Roland Morris Disability Questionnaire (RMDQ). English and Chinese databases were searched through December 2017. Cross-cultural adaptation and measurement properties were evaluated using the Guidelines for the Process of Cross-Cultural Adaptation of Self-Report Measures and the Quality Criteria for Psychometric Properties of Health Status Questionnaire. Among 34 studies, there were 31 RMDQ adaptations for 26 different languages/cultures. In the cross-cultural adaptation process, few studies reported expert committees completely constituted (3/31), and only ten studies complete the test of the pre-final version (10/31) due to insufficient sample sizes. As for the measurement properties, content validity (31/31) and construct validity (24/31) were assessed in most of the adaptations, whereas internal consistency (0/31), agreement (5/31), responsiveness (3/31), interpretability (6/31), and floor and ceiling effects (6/31) were not. The Hungarian and Moon's Korean adaptations were the highest quality translations. Where there were multiple adaptations for a language/culture, the Moon's Korean and Fan's simplified Chinese-Chinese Mainland adaptations are recommended over the other Korean or simplified Chinese-Chinese Mainland adaptations. Further studies are required to fully assess the measurement properties of the Arabic-Moroccan, Arabic-Tunisian, German- Austrian, Greek, Guajarati, Kim's Korean, Persian-Iranian, Polish, He's simplified Chinese-Chinese Mainland, Spanish, Spanish-Chilean, Thai, traditional Chinese-Taiwan, and Turkish adaptations of the RMDQ. Copyright © 2018. Published by Elsevier Inc.

Randvere Kool = Randvere School / Kristi Lents

Index Scriptorium Estoniae

Lents, Kristi, 1981-

2013-01-01

Kristi Lents-Esnari ja Marita Mätase (Allianss Arhitektid) kujundatud Randvere Kooli (G.H. Schüdlöffeli tee 4, Randvere küla, Viimsi) interjöörist. Hoone arhitekt Inga Raukas. Lühidalt Kristi Lents-Esnarist ja Marita Mätasest

Villa ekstravaganza / Oliver Orro

Index Scriptorium Estoniae

Orro, Oliver

2007-01-01

Villa (375 m2) Meriväljal. Arhitektid: Toomas Tammis, Inga Raukas, Tarmo Teedumäe, Arhitektuuriagentuur. Sisearhitekt Monika Löve. Hoone projekt: 2002-2006, valmis: 2006. I, II ja III korruse plaan, 8 värv. välis- ja 12 sisevaadet

Arenev Narva : kommentaar rahvusvahelisele Narva Peetri platsi planeeringu konkursile = Evolving Narva : comments on the internatinal planning competition for Peetri Square in Narva, Estonia / Kivi Sotamaa

Index Scriptorium Estoniae

Sotamaa, Kivi

2001-01-01

Mida peaks arvesse võtma Narva linna planeerimisel. Tingimustele vastavaist projektidest: Toomas Tammise, Inga Rauka ja Tarmo Teedumäe võidutööst, Jeffrey Turko (Urban Office, London) tööst, mis õigeks ajaks kohale ei jõudnud. 7 ill.

Narva keskosa planeeringu võistlus = Narva Central Area Planning Competition

Index Scriptorium Estoniae

2001-01-01

Rahvusvahelise arhitektuurivõistluse zürii koosseis. Preemiad: I - Inga Raukas, Toomas Tammis, Tarmo Teedumäe; II - Erik Nobel (Kopenhaagen); III - Mark Hemel, Barbara Kuit (London); ost - Villem Tomiste ja Veronika Valk ning Richard Havenhand, Gregg Wilson ja Steve Kemp (Lincoln, Inglismaa).

Pärnu mudaravila restaureerimine ja juurdeehitus = Restoration and extension of the Pärnu mud baths / Tarmo Teedumäe, Paco Ulman, Tüüne-Kristin Vaikla

Index Scriptorium Estoniae

Teedumäe, Tarmo, 1970-

2015-01-01

Restaureeritud ja uue juurdeehitusega Pärnu mudaravila Ranna puiestee 1, valminud 2014. Arhitektid Tarmo Teedumäe, Paco Ulman, Inga Raukas, Arhitektuuriagentuur, Allianss Arhitektid. Sisearhitektid Tüüne-Kristin Vaikla, Urmo Vaikla, Tuuli Trei, Margit Teikari (Vaikla Stuudio). 2014. aasta Kultuurkapitali Arhitektuuripreemia kandidaat

An interview with Murray Jackson by Jan Wiener.

Science.gov (United States)

Jackson, Murray

2011-04-01

Murray Jackson was among the early trainees at the Society of Analytical Psychology (SAP) drawn to Jungian ideas during the 1950s when the training was still relatively informal. He was born in Australia where he became a doctor and came to London to study psychiatry with a particular interest in psychosis. He was influenced by Michael Fordham with whom he had an analysis and his four papers, published in the Journal of Analytical Psychology in the early 1960s, contributed significantly to the growing interest in clinical technique, particularly transference, that developed in the Society at that time. Later, he retrained at the British Institute of Psychoanalysis in the Kleinian tradition and was the first consultant at the Maudsley Hospital to run a 10-bed unit for severely mentally ill patients applying psychoanalytic principles. In April 2010, Jan Wiener interviewed Murray Jackson in France, where he now lives in retirement, about his interest and subsequent disappointment in Jungian ideas as well as his involvement with the Society of Analytical Psychology at a particular point in its history. After a brief introduction, the interview is reproduced in full. © 2011, The Society of Analytical Psychology.

UBER DEN BEITRITT DER PLURIMODALITÄT DES VERSTEHENS DER NICHTEUROPÄISCHEN TRADITION. DISCOURS ÜBER DISCOURS. (PROBLEMATISIERUNG INITIERT MIT DEM WERK "CARSTVO ZNAKOVA" VON ROLAND BARTHES, AUGUST CESAREC, ZAGREB 1989

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Jadran Zalokar

1990-01-01

Full Text Available In diesem Text problematisiert der Verfasser manche grundsätzlicke Fragen des Verstehens nichteuropäischen Traditionen im Ganzen. Dabei analysiert er das Werk von Roland Barthes in Zusammenhang des Verstehens der Beziehung textuallen im Gegensatz zum geistlichen Tradition Japans, gleichzeitig auf die methodologisch wichtige Frage hinweisend. Alles enken und "Schreiben" darüber ist in nuce zweifelhaft. Das Denken des planetaren Polilogen als Multiloge verlangt einen strengen wissenschaftlichen Beitritt, aber auch einen metawissenschaftlichen und metaphilosphischen Einblick in das geistliche Wesen nichteuropäischen Tradition, weil es gleichmäßige Beachtung verschiedensten geistlichen Erfahrungen und Eingenartigkeiten des geistlichen Lebens aller Traditionen nötig ist und nurwissenschaftlicher und nurphilosophischer Beitritt ist nicht genügend.

The effectiveness of preplant seed bio-invigoration techniques using Bacillus sp. CKD061 to improving seed viability and vigor of several local upland rice cultivars of Southeast Sulawesi

Science.gov (United States)

Sutariati, G. A. K.; Bande, L. O. S.; Khaeruni, A.; Muhidin; Mudi, L.; Savitri, R. M.

2018-02-01

Research was aimed to evaluate the bio-invigoration techniques using Bacillus sp. CKD061 in improving seed viability and vigor of local upland rice. The research is arranged in factorial with completely randomized design (CRD). The different upland rice cultivars as first factor that consists of 11 cultivars, namely: Pae Tinangge, Pae Rowu, Pae Uwa, Pae Tanta, Pae Waburi-Buri, Pae Mornene, Pae Indalibana, Pae Lawarangka, Pae Huko, Pae Wagamba and Pae Momea. The second factor is the seed bio-invigoration technique, consists of 5 treatments, namely: without seed bio-invigoration (B0), NaCl + Bacillus sp. CKD061 (B1), KNO3 + Bacillus sp. CKD061 (B2), Ground burned-rice husk + Bacillus sp. CKD061 (B3), and Ground brick + Bacillus sp. CKD061 (B4). The results showed that seed bio-invigoration using Bacillus sp. CKD061 gave effect on the seed viability and vigor. Interaction of the seed bio-invigoration and upland rice cultivars were able to improve seed viability and vigor. Seed bio-invigoration ttreatment using ground brick + Bacillus sp. CKD061 was the best treatment, which could improve the viability and vigor of Pae Waburi-Buri, Pae Mornene and Pae Indalibana. The treatment increased vigor index by 133% in Pae Waburi-Buri and 127% in Pae Mornene, and Pae Indalibana compared with control.

New Discoveries about Janáček’s Choruses from 1873 to 1876 (Texts – Parts – Chronology)

Czech Academy of Sciences Publication Activity Database

Procházková, Jarmila

2017-01-01

Roč. 54, č. 2 (2017), s. 117-178 ISSN 0018-7003 Institutional support: RVO:68378076 Keywords : Leoš Janáček (1854-1928) * choruses * chronology of the early work * musical arrangements Subject RIV: AL - Art, Architecture, Cultural Heritage OBOR OECD: Performing arts studies (Musicology, Theater science, Dramaturgy)

Hoe hoger de haze bij diffuus glas, hoe hoger de meerproductie (interview met Jan Janse en Sonny Moerenhout)

NARCIS (Netherlands)

Kierkels, T.; Janse, J.; Moerenhout, S.

2012-01-01

Een vroege komkommerteelt onder diffuus glas gaf vanaf het begin een grotere opbrengst dan onder gewoon glas. Jan Janse van Wageningen UR Glastuinbouw durft na de reeks proeven in de afgelopen jaren de conclusie te trekken: hoe hoger de haze, hoe hoger de meerproductie. Dus ook in een vroege teelt.

Restoran Noa Miidurannas = Noa Restaurant in the Miiduranna area of Tallinn / Peeter Loo, Jan Skolimowski, Kaspar Kruuse, Tarmo Piirmets ; kommenteerinud Raivo Kotov

Index Scriptorium Estoniae

2015-01-01

Noa restoran Miidurannas Ranna tee 3, valminud 2014. Arhitektid Peeter Loo, Jan Skolimowski, Kaspar Kruuse (Kamp Arhitektid), sisearhitekt Tarmo Piirmets (Pink). Eesti Kultuurkapitali Arhitektuuri sihtkapitali arhitektuuripreemia 2014

De grote reis van Jan Alensoon (1683-1769): van zijn gezang was ‘ieder een verstelt en verwondert’

NARCIS (Netherlands)

Metzelaar, H.

2011-01-01

While most 17th and 18th century Grand Tours were trips of Europe meant to complete a young man’s education, Jan Alensoon is forty years old when he leaves Leiden in 1723. A learned connoisseur with clear opinions, Alensoon visits countless churches and palaces en route, especially in Italy, his

Uus Sakala arhitektuurivõistlus = The Uus Sakala architectural competition / Panu Lehtovuori

Index Scriptorium Estoniae

Lehtovuori, Panu, 1968-

2003-01-01

Žürii liige konkursist: keskuse asukohast ja programmist, praeguse Sakala keskuse kasutamisest, konkursi tulemusest. Teise vooru valiti kolm projekti: võidutöö "Küpsis" (autorid Toomas Tammis, Inga Raukas, Tarmo Teedumäe, ArhitektuuriAgentuur), "Ocularis" (autorid Siiri Vallner, Indrek Peil), "Sõstrad" (autor Veronika Valk)

The tourism potential of the commune Janów Podlaski and its evaluation of tourism appeal as compared to the administrative district of Biała Podlaska (Lublin voivodeship)

Science.gov (United States)

Skrzypczak, Andrzej; Chmielewska, Anna Beata

2009-01-01

The purpose of this thesis has been to evaluate tourism appeal of the commune of Janów Podlaski, as compared to the other communes in the administrative district of Biała Podlaska, and to analyse the recreational potential of the natural environment within the commune and it's present day infrastructure for tourism industry. For evaluation of the tourism attractiveness of the commune, based on comparative analysis, the method of synthetic measures was applied. The commune of Janów Podlaski belongs to one of the most attractive areas for tourists in the administrative district of Biała Podlaska. The attractiveness of the commune is associated with the Bug river, which flows across high-value landscapes and possess many ecological assets. Development of water tourism, however, is hindered by the fact that the Bug forms part of Poland's state border and it's water is rather polluted. Walking tourism in the commune of Janów Podlaski is encouraged owing to a well-developed and properly sing-posted networks of trails. The accommodation facilities are not evenly distributed as most of the rooms for tourists can be found in Janów Podlaski.

Avatars of a semiological adventure: the critical legacy of Roland Barthes and the drift of the structural / post-structural paradigm. An Introduction

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María Lourdes Gasillón

2016-03-01

Full Text Available The production of Roland Barthes (1915-1980 is abundant and varied to the point where critical studies about his writing –and even, according to the own semiologist– have established different “phases” in the development of his thought. In this paper, we intend to observe two of those moments in Barthes´ theorizing, which coincide with the prevailing theoretical currents in France between the ´60s and ´70s: the structuralism and the post-structuralism. With this goal, we will analize two central texts in the semiotics of Barthes: “Introduction to the structural analysis of narratives” (1966 and “From work to text” (1971. The comparison of both works will allow us to observe the epistemological point of view and the model which the author adopted in each moment. It includes a change of perspective on the language, setting the concept of “story” (and others related as “levels of consciousness”, “the story grammar”, distortion and expansion operations, etc. aside and using “text” as a methodological field held in language and his associated notions: game, practice, production, death of the author, among others.

Mälu pole ainult meil, vaid ka meie haigustel / Tiina Sarv

Index Scriptorium Estoniae

Sarv, Tiina, 1949-

2007-01-01

Pärnus toimunud Eesti arstide Astra Zeneca ABC-konverentsi märksõna oli mälu. Konverentsil esinesid professorid Endel Tulving, Alan Altraja ja Anto Raukas, dotsendid Tiina Ristimäe ja Ursel Soomets, kirjandusteadlane Rutt Hinrikus, zooloog Aleksei Turovski ning arstid Anu Ambos ja Riina Kütner

Théâtre, peinture, musique. La citation dans l’œuvre de Jan Fabre

Directory of Open Access Journals (Sweden)

Luc van den Dries

2017-06-01

Full Text Available In Jan Fabre’s theatre, references and allusions to different periods and movements of art history proliferate. This technique is not playful or postmodern. Rather, it belongs to the Brechtian tradition, as an original reflection on templates. In some cases, his quotational practice is so refined that it could be considered as a new form of adaptation, while, at the same time, self-quotation – which establishes a connection between different works and creative phases of the artist – is very frequent.

Cross-cultural Adaptation, Reliability, and Validity of the Yoruba Version of the Roland-Morris Disability Questionnaire.

Science.gov (United States)

Mbada, Chidozie Emmanuel; Idowu, Opeyemi Ayodiipo; Ogunjimi, Olawale Richard; Ayanniyi, Olusola; Orimolade, Elkanah Ayodele; Oladiran, Ajibola Babatunde; Johnson, Olubusola Esther; Akinsulore, Adesanmi; Oni, Temitope Olawale

2017-04-01

A translation, cross-cultural adaptation, and psychometric analysis. The aim of this study was to translate, cross-culturally adapt, and validate the Yoruba version of the RMDQ. The Roland-Morris Disability Questionnaire (RMDQ) is a valid outcome tool for low back pain (LBP) in clinical and research settings. There seems to be no valid and reliable version of the RMDQ in the Nigerian languages. Following the Guillemin criteria, the English version of the RMDQ was forward and back translated. Two Yoruba translated versions of the RMDQ were assessed for clarity, common language usage, and conceptual equivalence. Consequently, a harmonized Yoruba version was produced and was pilot-tested among 20 patients with nonspecific long-term LBP (NSLBP) for cognitive debriefing. The final version of the Yoruba RMDQ was tested for its construct validity and re-retest reliability among 120 and 87 patients with NSLBP, respectively. Pearson product moment correlation coefficient (r) of 0.82 was obtained for reliability of the Yoruba version of the RMDQ. The test-retest reliability of the Yoruba RMDQ yielded Cronbach alpha 0.932, while the intraclass correlation (ICC) ranged between 0.896 and 0.956. The analysis of the global scores of both the English and Yoruba versions of the RMDQ yielded ICC value of between 0.995 (95% confidence interval 0.996-0.997), with the item-by-item Kappa agreement ranging between 0.824 and 1.000. The external validity of RMDQ using Quadruple Visual Analogue Scale was r = -0.596 (P = 0.001). The Yoruba version of the RMDQ had no floor/ceiling effects, as no patient achieved either of the maximum or the minimum possible scores. The Yoruba version of the RMDQ has excellent reliability and validity and may be an appropriate outcome tool for clinical and research purposes among Yoruba-speaking patients with LBP. 3.

A Comparison of Back Pain Functional Scale with Roland Morris Disability Questionnaire, Oswestry Disability Index and Short Form 36-Health Survey.

Science.gov (United States)

Koç, Meltem; Bayar, Banu; Bayar, Kılıçhan

2017-10-03

A comparison study of Back Pain Functional Scale (BPFS) with Roland Morris Questionnaire (RMQ), Oswestry Disability Index (ODI) and Short Form 36-Health Survey (SF-36). The aim of this study is to investigate the correlation of BPFS with RMQ, ODI and SF-36. The primary goal in the treatment of patients with low back pain is to improve the patients' levels of activities and participation. Many questionnaires focusing on function have been developed in patients with low back pain. BPFS is one of these questionnaires. No studies have investigated the correlation of BPFS with ODI and SF-36. This study was conducted with 120 patients receiving outpatient and inpatient treatment in physiotherapy and rehabilitation units of a state hospital. BPFS, RMQ, ODI, SF-36 questionnaires were used to assess the disability in low back pain. Spearman and Pearson Correlation were used to compare the data obtained in the study. There was a good correlation among the five functional outcome measures (correlation r = -0.693 for BPFS/RMQ, r = -0.794 for BPFS/ODI, r = 0.697 for BPFS/SF-36 Physical function and r = 0.540 for BPFS/SF-36 Pain). BPFS demonstrated good correlation with RMQ, ODI, SF-36 physical function and SF-36 pain. 2.

O QUE É O ESPORTE? AS CONTRIBUIÇÕES SEMINAIS DE JOHAN HUIZINGA E ROGER CAILLOIS RESSIGNIFICADAS POR ROLAND BARTHES

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José Carlos Marques

2015-12-01

Full Text Available Em 1961, o pensador francês Roland Barthes (1915-1980 publicou o texto “Le sport et les hommes”, a partir de uma encomenda do canadense Hubert Aquin, que realizava um documentário com o mesmo título. O artigo oferece uma análise semiológica sobre a tourada na Espanha (a qual o próprio Barthes não sabe se a inclui na categoria de esporte, o automobilismo nos Estados Unidos, o ciclismo na França, o hóquei no gelo no Canadá e o futebol na Inglaterra. Longe dos termos técnicos das ciências do esporte e do linguajar acadêmico canônico, Barthes procura analisar os significados e a importância que o esporte assumiu na sociedade de massas do século XX, buscando interpretações e correlações entre a prática esportiva e as necessidades vitais do homem na contemporaneidade. Nossas reflexões procuram contrapor a contribuição barthesiana às obras seminais de dois outros autores europeus que, anos antes, propuseram uma leitura original sobre o esporte: são os casos de Johan Huizinga e o livro Homo Ludens (1938, e de Roger Caillois e Os Jogos e os Homens (1957.

Elamisväärse linna elukvaliteet ei ole seotud riigi või linna suurusega / Jan Gehl ; intervjueerinud Yoko Alender

Index Scriptorium Estoniae

Gehl, Jan, 1936-

2015-01-01

Yoko Alenderi (Yoko Oma OÜ) algatusel ja koostöös Eesti Kunstiakadeemiaga ilmus Taani urbanisti Jan Gehli raamat "Linnad inimestele" eesti keels. Yoko Alender selgitab projekti tagamaid ning uurib ka vanameistrilt endalt, mis teda elus ja töös tõdedeni on viinud ning kui helgena näeb ta linnade tulevikku

Remarks on Prof. Michał Kokowski’s comment about the studies into the life of Prof. Jan Czochralski (in Polish

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Paweł E. TOMASZEWSKI

2015-12-01

Full Text Available Remarks on the critical comments regarding the contents of the paper published after the presentation delivered by the biographer of Prof. Jan Czochralski. Unfortunately, Prof. Kokowski used an incorrect historical approach to such a short paper. The remarks are presented in four main points.

Meteorological and hydrographic data from a nearshore platform in Dauphin Island, AL from 22 Feb 1998 to 4 Jan 1999 (NODC Accession 0118645)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological and hydrographic data were collected from a monitoring station on Dauphin Island from Feb 1998 to Jan 1999. Variables measured include air...

Näitus "Iseolemise tahe. 90 aastat Eesti Vabariiki" = Exhibition "A will to be free. 90 years of the Republic of Estonia"

Index Scriptorium Estoniae

2009-01-01

Tallinnas Eesti Ajaloomuuseumi Maarjamäe hoones Eesti Vabariigi 90. aastapäevaks avatud näituse kujundusest, mis pälvis Eesti Sisearhitektide Liidu 2008. aasta näituse preemia. Kujunduse autorid Inga Raukas, Eva-Maria Gramakovski ja Oliver Soomets. Graafiline kujundus: Tuuli Aule. Loetletud kujundajate tähtsamaid töid

Pärnu mnt. ja Järvevana tee vahelise ala planeerimiskonkurss = Planning Competition of the Area between Järvevana and Pärnu Roads / Kalle Komissarov

Index Scriptorium Estoniae

Komissarov, Kalle, 1976-

2002-01-01

Konkursist, zürii koosseis, võidutöödest. Võistlusala oli AS-i "Kalev" ja Tallinna Piimatööstuse territoorium. Preemiad: I - Nikolai Volkov, Liis Sagadi, II - Tarmo Teedumäe, Renee Puusepp, Karli Luik, Toomas Tammis, Inga Raukas, III - Veronika Valk, ostupreemiad - Alver Trummal Arhitektid ja büroo Kosmos

Globaalarhitekti uus manifest / Karin Hallas-Murula

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Hallas-Murula, Karin, 1957-

2004-01-01

Hollandi arhitekt Rem Koolhaas'ist, kelle näitus "Content" Rotterdami Kunstihallis ning näitus "Start" Rotterdami Hollandi Arhitektuuriinstituudis on avatud 31. maini. Näituse "Content" kataloogist. 2000. a. sai R. Koolhaas Pritzkeri preemia, 2003. a. Praemium Imperiale, 2004. a. veebruaris RIBA kuldmedali. Kommenteerinud Andres Alver, Hanno Grossschmidt ja Inga Raukas

[Jan Kusberg, Kleine Geschichte St. Petersburgs. (Regensburg, 2009) ; Ingrid Bohn. Kleine Geschichte Stockholms. (Regensburg, 2008) ; Konrad Dittrich. Kleine Lübecker Stadtgeschichte. (Regensburg, 2007)] / Dennis Hortmuth

Index Scriptorium Estoniae

Hormuth, Dennis

2011-01-01

Arvustus: Jan Kusberg, Kleine Geschichte St. Petersburgs. (Regensburg, 2009) ; Ingrid Bohn. Kleine Geschichte Stockholms. (Regensburg, 2008) ; Konrad Dittrich. Kleine Lübecker Stadtgeschichte. (Regensburg, 2007)

Paeoniflorin inhibits the growth of bladder carcinoma via deactivation of STAT3

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Yang Jianhui

2018-06-01

Full Text Available Bladder cancer (BCa is one of the most common urinary cancers. The present study aims to investigate whether Paeoniflorin (Pae can exert inhibitory effects on BCa. The results showed that Pae inhibited proliferation of human BCa cell lines in a concentration- and time-dependent manner. Pae and cisplatin (Cis synergistically inhibited the growth of tumours in RT4-bearing mice. Pae treatment neutralized the body loss induced by Cis. Moreover, Pae induced apoptosis in RT4 cells and increased the activities of caspase3, caspase8 and caspase9. Western blotting and immunohistochemical analysis revealed that the phosphorylated signal transducer and activator of transcription-3 (p-STAT3 level were decreased in Pae-treated RT4 cells and Pae-treated tumour-bearing mice. Furthermore, STAT3 transcriptional target B-cell lymphoma-2 was decreased in Pae-treated RT4 cells. Interestingly, Pae prevented translocation of STAT3 to the nucleus in RT4 cells. Collectively, Pae inhibits the growth of BCa, at least in part, via a STAT3 pathway.

Drought-breaking love: An analysis of the moral values implied in ‘Drought’ by Jan Rabie

OpenAIRE

C. N. van der Merwe

1996-01-01

In this article the tension in 20th century literary theory between absolutism and relativism is discussed. It is argued that, in spite of a movement from absolutism towards relativism, the age-old “absolute” values of truth, beauty and goodness have never been totally forsaken in the creation and the contemplation of literature. In an analysis of “Drought” by Jan Rabie, it is indicated how these values are implied and invoked in Rabie's short story. In conclusion, the fundamental value of lo...

Viděno vlastníma očima. Nález neznámého konceptu autobiografie Pavla Janáka

Czech Academy of Sciences Publication Activity Database

Hnídková, Vendula

2008-01-01

Roč. 56, č. 3 (2008), s. 237-242, 273 ISSN 0049-5123 Institutional research plan: CEZ:AV0Z80330511 Keywords : Pavel Janák * Czech architecture of the 20th century * autobiography Subject RIV: AL - Art, Architecture, Cultural Heritage

Baustelle : Estland

Index Scriptorium Estoniae

2001-01-01

Eesti 1990. aastate arhitektuuri ülevaatenäitus Berliini Kunstide Akadeemias 15. 11. 2001-6. 01. 2002. Eksponeeritud fragmentaarne läbilõige Eesti arhitektuuribüroode töödest ja keskkonnast, milles ning mida nad ehitavad. Näituse toimkond: Liivi Künnapu, Vilen Künnapu, Leonhard Lapin, Irina Raud, Inga Raukas, Toomas Tammis

[Walter Leitsch. Sigismund III. von Polen und Jan Zamoysky : die Rolle Estlands in der Rivalität zwischen König und Hetman] / Martin Faber

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Faber, Martin

2009-01-01

Arvustus: Leitsch, Walter. Sigismund III. von Polen und Jan Zamoysky : die Rolle Estlands in der Rivalität zwischen König und Hetman. Wien : Verlag der Österreichischen Akademie der Wissenschaften, 2006

Comparative genome analysis provides insights into the evolution and adaptation of Pseudomonas syringae pv. aesculi on Aesculus hippocastanum.

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Sarah Green

Full Text Available A recently emerging bleeding canker disease, caused by Pseudomonas syringae pathovar aesculi (Pae, is threatening European horse chestnut in northwest Europe. Very little is known about the origin and biology of this new disease. We used the nucleotide sequences of seven commonly used marker genes to investigate the phylogeny of three strains isolated recently from bleeding stem cankers on European horse chestnut in Britain (E-Pae. On the basis of these sequences alone, the E-Pae strains were identical to the Pae type-strain (I-Pae, isolated from leaf spots on Indian horse chestnut in India in 1969. The phylogenetic analyses also showed that Pae belongs to a distinct clade of P. syringae pathovars adapted to woody hosts. We generated genome-wide Illumina sequence data from the three E-Pae strains and one strain of I-Pae. Comparative genomic analyses revealed pathovar-specific genomic regions in Pae potentially implicated in virulence on a tree host, including genes for the catabolism of plant-derived aromatic compounds and enterobactin synthesis. Several gene clusters displayed intra-pathovar variation, including those encoding type IV secretion, a novel fatty acid biosynthesis pathway and a sucrose uptake pathway. Rates of single nucleotide polymorphisms in the four Pae genomes indicate that the three E-Pae strains diverged from each other much more recently than they diverged from I-Pae. The very low genetic diversity among the three geographically distinct E-Pae strains suggests that they originate from a single, recent introduction into Britain, thus highlighting the serious environmental risks posed by the spread of an exotic plant pathogenic bacterium to a new geographic location. The genomic regions in Pae that are absent from other P. syringae pathovars that infect herbaceous hosts may represent candidate genetic adaptations to infection of the woody parts of the tree.

Diversities of phthalate esters in suburban agricultural soils and wasteland soil appeared with urbanization in China

International Nuclear Information System (INIS)

Kong Shaofei; Ji Yaqin; Liu Lingling; Chen Li; Zhao Xueyan; Wang Jiajun; Bai Zhipeng; Sun Zengrong

2012-01-01

The distribution of six priority phthalic acid esters (PAEs) in suburban farmland, vegetable, orchard and wasteland soils of Tianjin were obtained with gas chromatography-mass spectrometer analysis in 2009. Results showed that total PAEs varied from 0.05 to 10.4 μg g −1 , with the median value as 0.32 μg g −1 . Di-(2-ethylhexyl) phthalate and di-n-butyl phthalate are most abundant species. PAEs concentrations for the four types of soils exhibited decreasing order as vegetable soil > wasteland soil > farmland soil > orchard soil. PAEs exhibited elevated levels in more developed regions when compared with other studies. The agricultural plastic film could elevate the PAEs contents in soils. Principal component analysis indicated the emission from cosmetics and personal care products and plasticizers were important sources for PAEs in suburban soils in Tianjin. The higher PAEs contents in wasteland soils from suburban area should be paid more attention owing to large amounts of solid wastes appeared with the ongoing urbanization. - Highlights: ► PAEs levels in four types of soils in suburban area of Tianjin were studied. ► Vegetable soil and wasteland soil exhibited higher PAEs concentrations. ► PAEs in wasteland soils from suburban area of cities in China should be paid attention. - (1) Vegetable soil and wasteland soil exhibited higher PAEs concentrations; (2) PAEs in wasteland soils from suburban area of cities in China should be paid attention.

The pitfalls of qualified moral veganism. A critique of Jan Deckers' holistic health approach to animal ethics

OpenAIRE

Paez, Eze

2017-01-01

I critically examine Jan Deckers' position in Animal (De)liberation, where he defends two main views. The first is "qualified moral veganism": Most humans have a duty to abstain from consuming animal products, even if there are circumstances in which doing so is justified. The author argues, on the one hand, from a pan-sentientist view that attributes sentience to all elementary entities and their compounds. Thus, all living things (such as animals and plants) have a capacity for positive and...

Intra-vesical Prostatic Protrusion (IPP) Can Be Reduced by Prostatic Artery Embolization

Energy Technology Data Exchange (ETDEWEB)

Lin, Yen-Ting, E-mail: ymerically@gmail.com; Amouyal, Grégory, E-mail: gregamouyal@hotmail.com [Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges-Pompidou, Vascular and Oncological Interventional Radiology (France); Thiounn, Nicolas, E-mail: nicolas.thiounn@egp.aphp.fr [Assistance Publique Hopitaux de Paris, Hôpital Européen Georges-Pompidou, Urology (France); Pellerin, Olivier, E-mail: olivier.pellerin@aphp.fr [Université Paris Descartes, Sorbonne Paris-Cité (France); Pereira, Héléna, E-mail: helena.pereira@aphp.fr; Giudice, Costantino Del, E-mail: costantino.del-giudice@egp.aphp.fr; Déan, Carole, E-mail: carole.dean@aphp.fr [Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges-Pompidou, Vascular and Oncological Interventional Radiology (France); Sapoval, Marc, E-mail: marc.sapoval2@aphp.fr [Université Paris Descartes, Sorbonne Paris-Cité (France)

2016-05-15

BackgroundProstate artery embolization (PAE) is a new approach to improve lower urinary tract symptoms (LUTS) related to benign prostatic hyperplasia. PAE results in global reduction of prostate volume (PV). There are no data available on the efficacy of PAE in reducing intra-vesical prostatic protrusion (IPP), an anatomic feature that is clinically related with bladder outlet obstruction and LUTS.ObjectiveTo assess the results of PAE in patients with significant IPP due to median lobe hyperplasia and to compare the IPSS decrease and IPP change.Material and MethodsProspective analysis of 18 consecutive patients with significant IPP (>5 mm) related to median lobe hyperplasia undergoing PAE using 30–500-μm-calibrated trisacryl microspheres. We measured IPP on sagittal T2-weighted images before and 3 months after PAE. IPSS and clinical results were also evaluated at 3 months.ResultsPAE resulted in significant IPP reduction (1.57 cm ± 0.55 before PAE and 1.30 cm ± 0.46 after PAE, p = 0.0005) (Fig. 1) with no complication. IPSS, quality of life (QoL), total prostate-specific antigen (PSA) level, and PV showed significant reduction after PAE, and maximum urinary flow rate (Q{sub max}) showed significant increase after PAE. No significant change of International Index of Erectile Function (IIEF) for clinical evaluation after PAE. A significant correlation was found between the IPP change and the IPSS change (r = 0.636, p = 0.0045).ConclusionPatients had significant IPP reduction as well as significant symptomatic improvement after PAE, and these improvements were positively correlated.

Rannikuprojekt arhitektuurimuuseumis

Index Scriptorium Estoniae

1998-01-01

1. aprillist Rotermanni soolalaos rahvusvahelise "Coast Wise Europe" projekti raames näitus "CWEESTI" Rotterdami Arhitektuuri Akadeemia algatatud rahvusvahelisest projektist "Coast Wise Europe", mis keskendub Euroopa ranniku probleemidele ja turismi fenomeni uurimisele. Projekti teemast, eesmärgist, osalejatest, Eesti Kunstiakadeemia arhitektuuri teaduskonna osalemisest projektis. CWE atlase Eesti peatüki koostamist juhendasid I. Raukas, I. Valdur, M. Kaasik.

Pollution characteristics and health risk assessment of phthalate esters in urban soil in the typical semi-arid city of Xi'an, Northwest China.

Science.gov (United States)

Wang, Lijun; Liu, Mengmei; Tao, Wendong; Zhang, Wenjuan; Wang, Li; Shi, Xingmin; Lu, Xinwei; Li, Xiaoping

2018-01-01

A total of 62 urban soil samples were collected in the city of Xi'an in Northwest China, and analyzed for six U.S. Environmental Protection Agency priority phthalate esters (PAEs). Unlike earlier studies on PAEs in agricultural soil as well as urban soil in humid climates, this paper for the first time comprehensively assessed pollution characteristics and health risks of human exposure to PAEs in urban soil in a typical semi-arid climate. The total concentrations of the six PAEs (Σ6PAEs) in the urban soil varied between 193.0 and 19146.4 μg kg -1 with a mean of 1369.3 μg kg -1 . The PAEs were dominated by di-n-butyl phthalate and di(2-ethylhexyl) phthalate. Magnetic susceptibility and soil texture were controlling factors influencing the concentrations of PAEs in the urban soil. The concentrations of benzyl butyl phthalate, di(2-ethylhexyl) phthalate, and Σ6PAEs increased from the first to third ring roads, while the concentrations of di-n-octyl phthalate decreased. Relatively higher levels of PAEs were observed in industrial, traffic, and residential areas. The PAEs in the urban soil originated mainly from the application of plasticizers or additives, use of cosmetics and personal care products, emissions of construction materials and home furnishings, industrial processes, and atmospheric deposition. The concentrations of some PAEs in the urban soil exceeded soil allowable concentrations and environmental risk levels. The non-cancer and carcinogenic risks of human exposure to the PAEs were relatively low. Copyright © 2017 Elsevier Ltd. All rights reserved.

KEARIFAN BUDAYA LOKAL MADURA SEBAGAI MEDIA PERSUASIF (Analisis Semiotika Komunikasi Roland Barthes dalam Iklan Samsung Galaxy Versi Gading dan Giselle di Pulau Madura

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Sri Wahyuningsih

2014-12-01

Full Text Available This article aims to provide an overview of the cultural wisdom of Madura in advertisement Samsung Galaxy Ivory version by Indonesian celebritis Gading and Giselle in the island of Madura. This study, usin a semiotic analysis of Roland Barthes, tried to unlock the meaning of the signs that are used and re veal the hidden message contained in this advertisement. The author conducted a qualitative study with a research focus on scenes depicting local wisdom of Madurese culture, and then select scenes in advertising that represents local cultural wisdom Madura. Local knowledge of Madurese culture has its own persuasive power. Theme choice by producer of the advertisement is very interesting and has its own character, especially of cattle races, clothing style Madurese, as well as their language and dialect. Madura Island in East Java island region known as the island of salt, and exotic, so well known nationally and internationally. The results of the analysis of mobile phone mentioned found some connotations as follows: (1 the existence of a form of Madurese community thanksgiving in the lens, and (2 cow races, clothing Madura, and language of madurese is indigenous culture of Madura.

Individuality as expression of human emancipation. Reflection on the conception of Jan Szczepański

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Tomasz Leszniewski

2017-01-01

Full Text Available The paper raises the issue of “the individual factor” in the sociological reflection on social reality. Referring to Jan Szczepański's concept of individuality it analyzes the problem of human nature and the inner world as a source of resistance to the negative consequences of collective mechanisms. The paper presents the thesis that individuality is the culmination of the process of human development. However, in the context of socio-cultural category of individuality, it is an attempt to transcend the current data and the tension between individual- ism and collectivism. Human Individuality is a potential criticism regarding the public order and social change.

Remarks to Dr. Paul E. Tomaszewski’s comments on the research of Jan Czochralski’s curriculum vitae (a reply (in Polish

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Michał KOKOWSKI

2015-12-01

Full Text Available The author replies to the text entitled “Remarks to the comment by Prof.  Michal Kokowski on the research of Jan Czochralski’s biography” by Dr. Paweł E. Tomaszewski (2015, highlighting the key contentious issues, including the need to rely systematically on historical sources and the criticism thereof.

Occurrence and Residue Pattern of Phthalate Esters in Fresh Tea Leaves and during Tea Manufacturing and Brewing.

Science.gov (United States)

Liu, Pingxiang; Chen, Hongping; Gao, Guanwei; Hao, Zhenxia; Wang, Chen; Ma, Guicen; Chai, Yunfeng; Zhang, Lin; Liu, Xin

2016-11-23

The residues of 16 phthalate esters (PAEs) in fresh tea leaves and made tea were determined via gas chromatography-tandem mass spectrometry to study their distribution and degradation characteristics during tea planting and processing. Five PAEs were detected in all fresh tea leaves, and higher concentrations were detected in mature leaves. The distribution of PAEs in fresh tea leaves ranged from 69.7 to 2244.0 μg/kg. The degradative percentages of ∑ 5 PAEs during green tea manufacturing ranged from 61 to 63% and were significantly influenced by the drying process. The transfer rates of PAEs-D 4 ranged from 5.2 to 100.6%. PAEs with a high water solubility showed the highest transfer coefficient in the range of 91.8-100.6%, whereas PAEs with a high log K ow showed a low leaching efficiency below 11.9%. These results benefit the risk evaluation and establishment of a maximum residue limit for PAEs in tea.

Attitudes toward physical activity and exercise: comparison of memory clinic patients and their caregivers and prediction of activity levels.

Science.gov (United States)

O'Connell, Megan E; Dal Bello-Haas, Vanina; Crossley, Margaret; Morgan, Debra G

2015-01-01

Regular physical activity and exercise (PA&E) reduces cognitive aging, may delay dementia onset, and for persons with dementia, may slow progression and improve quality of life. Memory clinic patients and caregivers described their PA&E and completed the Older Persons' Attitudes Toward Physical Activity and Exercise Questionnaire (OPAPAEQ). Caregivers and patients differed in their PA&E attitudes: patients were less likely to believe in the importance of PA&E for health promotion. PA&E attitudes were explored as predictors of self-reported exercise habits. Belief in the importance of high intensity exercise for health maintenance was the only variable that significantly predicted engagement in regular PA&E. Moreover, caregivers' attitudes toward high intensity exercise predicted memory patients' participation in PA&E. These findings may aid in development of exercise interventions for people with memory problems, and suggest that modification of specific attitudes toward exercise is an important component to ensure maximum participation and engagement in PA&E.

Earlier production, more and heavier fruits: The higher the haze, the greater the extra production (interview with Jan Janse and Sonny Moerenhout)

NARCIS (Netherlands)

Kierkels, T.; Janse, J.; Moerenhout, S.

2012-01-01

Early cucumbers grown under diffuse glass have a larger yield than those grown under normal glass right from the start of the cultivation. Following a series of trials carried out over the last few years, Jan Janse of Wageningen UR Greenhouse Horticulture concludes: the higher the haze, the greater

Chronic Supplementation of Paeonol Combined with Danshensu for the Improvement of Vascular Reactivity in the Cerebral Basilar Artery of Diabetic Rats

Science.gov (United States)

Hu, Jing; Li, Ya-Ling; Li, Zi-Lin; Li, Hua; Zhou, Xuan-Xuan; Qiu, Peng-Cheng; Yang, Qian; Wang, Si-Wang

2012-01-01

One of the leading causes of death in the world is cerebrovascular disease. Numerous Chinese traditional medicines, such as Cortex Moutan (root bark of Paeonia suffruticosa Andrew) and Radix Salviae miltiorrhizae (root and rhizome of Salvia miltiorrhiza Bunge), protect against cerebrovascular diseases and exhibit anti-atherosclerotic effects. Traditional medicines have been routinely used for a long time in China. In addition, these two herbs are prescribed together in clinical practice. Therefore, the pharmacodynamic interactions between the active constituents of these two herbs, which are paeonol (Pae) and danshensu (DSS), should be particularly studied. The study of Pae and DSS can provide substantial foundations in understanding their mechanisms and empirical evidence to support clinical practice. This study investigated the effects and possible mechanisms of the pharmacodynamic interaction between Pae and DSS on cerebrovascular malfunctioning in diabetes. Experimental diabetes was induced in rats, which was then treated with Pae, DSS, and Pae + DSS for eight weeks. Afterward, cerebral arteries from all groups were isolated and equilibrated in an organ bath with Krebs buffer and ring tension. Effects of Pae, DSS, and Pae + DSS were observed on vessel relaxation with or without endothelium as well as on the basal tonus of vessels from normal and diabetic rats. Indexes about oxidative stress were also determined. We report that the cerebral arteries from diabetic rats show decreased vascular reactivity to acetylcholine (ACh) which was corrected in Pae, DSS, and Pae + DSS treated groups. Furthermore, phenylephrine (PE)-induced contraction response decreased in the treated groups. Phenylephrine and CaCl2-induced vasoconstrictions are partially inhibited in the three treated groups under Ca2+-free medium. Pre-incubated with tetraethylammonium, a non-selective K+ channel blocker, the antagonized relaxation responses increased in DSS and Pae + DSS treated diabetic

Review of the geographic distribution of Micrurus decoratus (Jan, 1858 (Serpentes: Elapidae

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Rodrigo Castellari Gonzalez

2014-08-01

Full Text Available Micrurus decoratus (Jan, 1858 is a poorly known species of coral snake, with a controversial history concerning its geographical range. The lack of consensus among researchers, since its original description, is largely due to the reporting of erroneous localities in publications. Herein we present the geographical range for the species based on the review of 184 records from 67 different municipalities in Brazil, including two new records for the state of Espírito Santo, extending its distribution to ca. 300 km northward from the previous northernmost locality. We also comment on doubtful records for the states of Rio Grande do Sul and Bahia, which contain no accurate data. We restrict the occurrence of Micrurus decoratus to the Atlantic Rainforest, with elevation range from 400 up to 1,600 m in the Brazilian states of Santa Catarina, Paraná, São Paulo, Rio de Janeiro, Minas Gerais and Espírito Santo.

[Characteristics of Phthalic Acid Esters in Agricultural Soils and Products in Areas of Zhongshan City, South China].

Science.gov (United States)

Li, Bin; Wu, Shan; Liang, Jin-ming; Liang, Wen-li; Chen, Gui-xian; Li, Yong-jun; Yang, Guo-yi

2015-06-01

In order to investigate and assess the pollution level of phthalic acid esters (PAEs) in farm soils and products from typical agricultural fields in areas of Zhongshan City, Guangdong Province, South China, 65 topsoil and 37 agricultural product samples were collected and contents of 6 PAEs compounds that classified by the U. S. Environmental Protection Agency (EPA) as priority pollutants were determined by the GC-FID. The results indicated that total contents of the PAEs (∑ PAEs) in soils ranged from 0. 14 to 1. 14 mg x kg(-1), and the mean value was 0.43 mg x kg(-1), with the detected ratio of 100%. Various concentrations of PAEs differed in three land-use types were ordered by vegetable soil > orchard soil > paddy soil. Comparing with six U.S. EPA priority pollutants of PAEs, the contents of Di-n-butyl phthalate (DBP) and Dimethyl phthalate ( DMP) in soils exceeded the control limits of PAEs in the American soil by 93.85% and 27.69% respectively, but the rest four PAEs compounds were lower than the control limits. Generally, the pollution level of soils contaminated by PAEs in agricultural fields of Zhongshan City was relatively low. The contents of 3 PAEs in agricultural products ranged from 0.15 to 3.15 mg x kg(-1) with the average of 1.12 mg x kg(-1), which was lower than the suggested standards in USA and Europe and with low health risk. Meanwhile, ∑ PAEs concentrations in vegetables were higher than those both in rice and fruits. DBP and DEHP were the main components of PAEs both in agricultural soils and products, with higher percentage contents and detected ratio. ∑ PAEs and DBP contents in various agricultural products-soils had a significantly positive correlation, with Pearson coefficients (r) in vegetables-vegetable soils were 0.81 (P = 0.000), 0.75 (P = 0.000), and corresponding r among rice-paddy soil and fruits-fruit soils were 0.74 (P = 0.036), 0.65 (P = 0.041) and 0.66 (P = 0.029), 0.78 (P = 0.045), respectively. Although there existed a

Como colocar em prática o Plano de Atendimento às Emergências (PAE no laboratório clínico How to implement the Plan of Care for Emergencies (LAP in the clinical laboratory

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Maria Elizabete Mendes

2011-06-01

Full Text Available INTRODUÇÃO: A situação socioeconômica e ambiental na qual os laboratórios clínicos vivem, aliada aos riscos ampliados do negócio nos dias atuais, exige dos dirigentes a elaboração de um plano de segurança para situações de catástrofes. OBJETIVO: Esse plano é útil para garantir a continuidade do negócio e sua recuperação após a crise. MÉTODO: O Plano de Atendimento à Emergência (PAE é apresentado como um conjunto de procedimentos estruturados para a obtenção de respostas rápidas, adestradas e eficientes em situações de emergência no laboratório. CONCLUSÃO: Ele visa prevenir ou mitigar as eventuais consequências adversas para segurança, saúde e meio ambiente no âmbito laboratorial. RESULTADO: Este artigo discute a aplicabilidade, as responsabilidades, a elaboração e a manutenção, assim como suas implicações na rotina laboratorialINTRODUCTION: Nowadays, the environmental and socioeconomic contexts in which clinical laboratories are set, coupled with increased business risks, require the formulation of an emergency care plan in case of natural disasters. OBJECTIVE: This plan is useful to ensure business continuity and recovery after crisis. METHOD: The Emergency Care Plan (PAE is presented as a structured set of procedures for obtaining rapid, efficient and trained responses in emergency situations. CONCLUSION: It aims at preventing or mitigating occasional adverse consequences regarding safety, health and environment in clinical laboratories. RESULTS: This article discusses the applicability, responsibilities, development and maintenance as well as their corresponding implications in laboratory procedures

Pemisahan dan Pemurnian Phthalic Acid Ester dari Minyak Nyamplung

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William Ekaputra Taifan

2013-09-01

Full Text Available Minyak nyamplung dikenal sebagai minyak yang tidak dapat dikonsumsi. Oleh sebab itu, penelitian tentang minyak ini hanya fokus pada konversi minyak menjadi biodiesel. Pada penelitian ini, kami berusaha untuk memisahkan resin beracun dari fraksi metanol menggunakan ekstraksi pelarut diikuti kolom kromatografi. Resin beracun ini diidentifikasi sebagai phthalic acid ester (PAE. PAE ini biasanya digunakan sebagai zat aditif di industri polimer. Minyak nyamplung mengandung 1,8% PAE, yang masih jauh melebihi nilai ambang batas. Isolasi PAE dari minyak ini diharapkan dapt mengubah minyak yang tidak dapat dikonsumsi menjadi suplemen makanan yang bernilai. Proses isolasi PAE dimulai dengan memisahkan senyawa yang diinginkan dari lipid menggunakan ekstraksi pelarut bertingkat dengan metanol dan n-heksan. Analisa mass spectra dari fraksi pertama dan fraksi kedua metanol menunjukkan kandungan PAE sebesar 60% dan 6% pada tiap fraksi. Fraksi heksan tidak mengandung PAE. PAE yang terkandung pada fraksi metanol diisolasi lebih lanjut dari asam lemak menggunakan liquid column chromatography dengan n-heksan – etil asetat sebagai mobile phase. Bis- 2ethylhexyl phthalate diidentifikasi pada ketiga fraksi sesuai dengan hasil analisa GC-MS. Fraksi pertama diambil pada kondisi mobile phase 5% etil asetat, sedangkan fraksi kedua merupakan campuran 5% etil asetat dan 10% etil asetat. Fraksi ketiga diambil pada kondisi mobile phase 10% etil asetat mengandung PAE sebesar 98%. Fraksi keempat merupakan campuran 10% dan 15% mobile phase dan mengandung PAE sebesar 97%. Akhirnya, kandungan PAE pada fraksi metanol sebesar 58%. Dari hasil analisa, dapat disimpulkan bahwa mobile phase yang optimum untuk kromatografi adalah 10- 15% etil asetat dalam n-heksan.

O perníkové chaloupce na Hukvaldech aneb Lidka Sládkvá vypráví Janáčkovi pohádku

Czech Academy of Sciences Publication Activity Database

Procházková, Jarmila

-, č. 10 (2006), s. 91-92 ISSN 1801-4755 Institutional research plan: CEZ:AV0Z90580513 Keywords : Leoš Janáček * melodies of speech * Moravian folk tale * Hukvaldy Subject RIV: AC - Archeology, Anthropology, Ethnology

Mood and implicit alcohol expectancy processes: predicting alcohol consumption in the laboratory.

Science.gov (United States)

Wardell, Jeffrey D; Read, Jennifer P; Curtin, John J; Merrill, Jennifer E

2012-01-01

Implicit positive alcohol expectancy (PAE) processes are thought to respond phasically to external and internal stimuli-including mood states-and so they may exert powerful proximal influences over drinking behavior. Although social learning theory contends that mood states activate mood-congruent implicit PAEs, which in turn lead to alcohol use, there is a dearth of experimental research examining this mediation model relative to observable drinking. Moreover, an expectancy theory perspective might suggest that, rather than influencing PAEs directly, mood may moderate the association between PAEs and drinking. To test these models, this study examined the role of mood in the association between implicitly measured PAE processes (i.e., latency to endorse PAEs) and immediate alcohol consumption in the laboratory. Gender differences in these processes also were examined. College students (N = 146) were exposed to either a positive, negative, or neutral mood induction procedure, completed a computerized PAE reaction time (RT) task, and subsequently consumed alcohol ad libitum. The mood manipulation had no direct effects on drinking in the laboratory, making the mediation hypothesis irrelevant. Instead, gender and mood condition moderated the association between RT to endorse PAEs and drinking in the laboratory. For males, RT to tension reduction PAEs was a stronger predictor of volume of beer consumed and peak blood alcohol concentration in the context of general arousal (i.e., positive and negative mood) relative to neutral mood. RT to PAEs did not predict drinking in the laboratory for females. The results show that PAE processes are important determinants of immediate drinking behavior in men, suggesting that biased attention to mood-relevant PAEs-as indicated by longer RTs-predicts greater alcohol consumption in the appropriate mood context. The findings also highlight the need to consider gender differences in PAE processes. This study underscores the need for

Incidence, risk factors, treatment and prognosis of popliteal artery embolization in the superficial femoral artery interventions.

Directory of Open Access Journals (Sweden)

Weiwei Wu

Full Text Available OBJECTIVE: Percutaneous transluminal angioplasty and stenting (PTA + stent has gained acceptance as a primary treatment modality for the superficial femoral artery (SFA diseases. Popliteal artery embolization (PAE is a severe complication in SFA interventions. The purpose of this study was to evaluate the incidence, risk factors, treatment and prognosis of PAE in primary SFA PTA + stent. METHODS: Chronic SFA arteriosclerosis cases that underwent primary PTA + stent were reviewed from a retrospectively maintained database. Runoff vessels were evaluated in all cases before and after the interventions for PAE detection. The primary patency, secondary patency and limb salvage rates were calculated using Kaplan-Meier analysis and compared using log-rank analysis. Cox multivariate regression was performed to evaluate predictors of patency and limb salvage rates. RESULTS: There were 436 lesions treated in 388 patients with 10 PAE events (2.3% in total. PAE rate was significantly higher in Transatlantic Inter-Society Consensus (TASC C/D group compared with TASC A/B group (OR = 8.91, P = .002, in chronic total occlusion (CTO lesions compared with stenotic lesions (P<.0001, and in group with history of cerebral ischemic stroke (OR = 6.11, P = .007. PAE rates were not significantly affected by age, sex, smoking, hypertension, diabetes, hyperlipidemia and runoff status. The binary logistic regression showed that only the TASC C/D was an independent predictor of PAE (P = .031. The 12-month and 24-month primary patency, secondary patency and limb salvage rates in PAE group showed no significant differences comparing with non-PAE group. CONCLUSIONS: PAE is a rare event in primary SFA PTA + stent. TASC C/D lesion, CTO and cerebral ischemic stroke history are risk factors for PAE. PAE is typically reversible by comprehensive techniques. If the popliteal flow is restored in time, PAE has no significant effect on long-term patency and limb

Abra esta carta após minha morte: escrita como testamento na correspondência entre Jan Hus e seu discípulo = Open this letter after my death: writing as testament in the correspondence between Jan Hus and his disciple

Directory of Open Access Journals (Sweden)

Thiago Borges de Aguiar

2011-01-01

Full Text Available O clérigo e educador Jan Hus, morto em 1415 pela fogueira do Concílio de Constança, escreveu duas cartas para seu discípulo Martin de Volyně, nas quais deixou um conjunto de instruções de distribuição de seus bens materiais e um rol de ensinamentos espirituais. As cartas eram semelhantes, sendo que a primeira só deveria ser aberta caso Martin recebesse de fonte segura a notícia da morte de Hus. Este texto analisa o contexto e o conteúdo dessas cartas em busca de indícios (conceito baseado no historiador Carlo Ginzburg de uma ação educativa da parte do remetente e de uma transmissão de seu lugar de mestre para seu discípulo.The priest and educator Jan Hus, who was killed by fire in 1415 the Council of Constance, wrote two letters to his disciple Martin of Volyne, in which left a set of instructions for distribution of their material possessions and an list of spiritual teachings. The letters were similar, and the first should only be opened if Martin received from a reliable source news of the death of Hus. This paper examines the context and content of these letters for clues (concept based on historian Carlo Ginzburg from an educational activity on the part of the sender and the transmission of his place of master to his disciple.

24 CFR 401.310 - Conflicts of interest.

Science.gov (United States)

2010-04-01

... prevent the PAE or other restricted person from acting at all times in the best interests of HUD; (ii) Has... control of the PAE, or is under common control with the PAE; or any employee, agent or contractor of the PAE, or employee of such agent or contractor, who will perform or has performed services under a PRA...

Influence of water solubility, side chain degradability and side chain configuration on the degradation of phthalic acid esters under methanogenic conditions

Energy Technology Data Exchange (ETDEWEB)

Alnervik, M.

1996-12-31

Water solubility and degradability of side chains estrifying phthalic acid are factors possible to influence the degradation of phthalic acid esters (PAEs). To investigate the importance of these factors degradation of butyl 2-ethylhexyl phthalate (BEHP), bis(2-ethylhexyl) phthalate (DEHP), dibutyl phthalate (DBP), dihexyl phthalate (DHP), dioctyl phthalate (DOP) and didecyl phthalate (DDP) were examined under methanogenic conditions as well as was the degradability of the alcohols estrifying these PAEs. We also investigated if the degradation of resistant PAEs could be stimulated by the addition of a degradable PAE. Synthesis of degradation intermediates and two methods for PAE analyses are presented. The investigation showed that all alcohols were degraded to methane and carbon dioxide and that the degradation of PAE occurred in incubations amended with BBP, BEHP, DHP and DBP, whilst DEHP, DOP and DDP were unaffected throughout the experimental period. BBP added to incubations with DEHP, could not stimulate DEHP degradation. In conclusion, the degradability of alcohols estrifying phthalic acid in this study does not affect the anaerobic degradability of PAEs. Water solubility of a PAE can not be rejected as a factor limiting phthalate degradation under methanogenic conditions. Anaerobic degradation of persistent PAEs can not be stimulated by mixing it with a degradable phthalate. 23 refs, 11 figs, 2 tabs

Physical activity: does environment make a difference for tension, stress, emotional outlook, and perceptions of health status?

Science.gov (United States)

Puett, Robin; Teas, Jane; España-Romero, Vanesa; Artero, Enrique Garcia; Lee, Duck-chul; Baruth, Meghan; Sui, Xuemei; Montresor-López, Jessica; Blair, Steven N

2014-11-01

The importance of physical activity for health is well-established. Questions remain whether outdoor exercise additionally benefits overall mental and physical well-being. Using cross-sectional data from the Aerobics Center Longitudinal Study, we examined relationships of physical activity environment (PAE) with reported tension, stress, emotional outlook, and health. 11,649 participants were included. 18% exercised indoors, 54% outdoors, and 28% in both. Participants who exercised partially or entirely outdoors exercised more. In fully adjusted models, for women combined PAE was protective for worse emotional outlook (OR: 0.72; 95% CI: 0.52-0.98). Combined PAE was also protective for reported poor health (OR for women: 0.63; 95% CI: 0.44-0.91; OR for men: 0.75; 95% CI: 0.61-0.92). Amount of physical activity modified PAE relationships with outcomes. Combined and outdoor PAE were more consistently protective for worse outcomes among high activity participants. Regardless of PAE, better outcomes were observed in active versus inactive participants. The current study suggests addition of outdoor PAE may be linked with better stress management, outlook and health perceptions for more active populations, whereas indoor PAE may be more important for low active populations. Further research should examine the order of causation and whether type of outdoor PAE (eg, urban, natural) is important.

Potential mechanisms of phthalate ester embryotoxicity in the abalone Haliotis diversicolor supertexta

Energy Technology Data Exchange (ETDEWEB)

Zhou Jin [L-304, Life Sciences Division, Graduate School at Shenzhen, Tsinghua University, Shenzhen University Town, Xili, Shenzhen City 518055 (China); Cai Zhonghua, E-mail: caizh@sz.tsinghua.edu.cn [L-304, Life Sciences Division, Graduate School at Shenzhen, Tsinghua University, Shenzhen University Town, Xili, Shenzhen City 518055 (China); Key Laboratory of Aquatic-Ecology, Tianjin Agricultural University, Lishui Road 112, Tianjin 300384 (China); Xing Kezhi [Key Laboratory of Aquatic-Ecology, Tianjin Agricultural University, Lishui Road 112, Tianjin 300384 (China)

2011-05-15

The effects and associated toxicological mechanisms of five phthalate esters (PAEs) on abalone embryonic development were investigated by exposing the embryos to a range of PAEs concentrations (0.05, 0.2, 2 and 10 {mu}g/mL). The results showed that PAEs could significantly reduce embryo hatchability, increase developmental malformations, and suppress the metamorphosis of abalone larvae. The possible toxicological mechanisms of PAEs to abalone embryos included, affecting the Na{sup +}-K{sup +}-pump and Ca{sup 2+}-Mg{sup 2+}-pump activities, altering the peroxidase (POD) level and the malondialdehyde (MDA) production, damaging the extraembryonic membranes structure, as well as disrupting endocrine-related genes (gpx, cyp3a, and 17{beta}-hsd 12) expression properties. Taken together, this work showed that PAEs adversely affected the embryonic ontogeny of abalone. The abilities of PAEs affecting the osmoregulation, inducing oxidative stress, damaging embryo envelope structure, and causing physiological homeostasis disorder, are likely to be a part of the common mechanisms responsible for their embryonic toxicity. - Highlights: > PAEs affected abalone hatchability, morphogenesis and metamorphosis behavior. > The toxicity of the five PAEs to embryogenesis was ranked as DBP > DEP > DMP > DOP > DEHP. > The osmoregulation disorder and oxidative damage are the potential mechanisms. - Potential mechanisms of PAEs on abalone embryogenesis are osmoregulation disorder, oxidative damage and physiological dysfunction.

Potential mechanisms of phthalate ester embryotoxicity in the abalone Haliotis diversicolor supertexta

International Nuclear Information System (INIS)

Zhou Jin; Cai Zhonghua; Xing Kezhi

2011-01-01

The effects and associated toxicological mechanisms of five phthalate esters (PAEs) on abalone embryonic development were investigated by exposing the embryos to a range of PAEs concentrations (0.05, 0.2, 2 and 10 μg/mL). The results showed that PAEs could significantly reduce embryo hatchability, increase developmental malformations, and suppress the metamorphosis of abalone larvae. The possible toxicological mechanisms of PAEs to abalone embryos included, affecting the Na + -K + -pump and Ca 2+ -Mg 2+ -pump activities, altering the peroxidase (POD) level and the malondialdehyde (MDA) production, damaging the extraembryonic membranes structure, as well as disrupting endocrine-related genes (gpx, cyp3a, and 17β-hsd 12) expression properties. Taken together, this work showed that PAEs adversely affected the embryonic ontogeny of abalone. The abilities of PAEs affecting the osmoregulation, inducing oxidative stress, damaging embryo envelope structure, and causing physiological homeostasis disorder, are likely to be a part of the common mechanisms responsible for their embryonic toxicity. - Highlights: → PAEs affected abalone hatchability, morphogenesis and metamorphosis behavior. → The toxicity of the five PAEs to embryogenesis was ranked as DBP > DEP > DMP > DOP > DEHP. → The osmoregulation disorder and oxidative damage are the potential mechanisms. - Potential mechanisms of PAEs on abalone embryogenesis are osmoregulation disorder, oxidative damage and physiological dysfunction.

Effects of early-life adversity on immune function are mediated by prenatal environment: Role of prenatal alcohol exposure.

Science.gov (United States)

Raineki, Charlis; Bodnar, Tamara S; Holman, Parker J; Baglot, Samantha L; Lan, Ni; Weinberg, Joanne

2017-11-01

The contribution of the early postnatal environment to the pervasive effects of prenatal alcohol exposure (PAE) is poorly understood. Moreover, PAE often carries increased risk of exposure to adversity/stress during early life. Dysregulation of immune function may play a role in how pre- and/or postnatal adversity/stress alters brain development. Here, we combine two animal models to examine whether PAE differentially increases vulnerability to immune dysregulation in response to early-life adversity. PAE and control litters were exposed to either limited bedding (postnatal day [PN] 8-12) to model early-life adversity or normal bedding, and maternal behavior and pup vocalizations were recorded. Peripheral (serum) and central (amygdala) immune (cytokines and C-reactive protein - CRP) responses of PAE animals to early-life adversity were evaluated at PN12. Insufficient bedding increased negative maternal behavior in both groups. Early-life adversity increased vocalization in all animals; however, PAE pups vocalized less than controls. Early-life adversity reduced serum TNF-α, KC/GRO, and IL-10 levels in control but not PAE animals. PAE increased serum CRP, and levels were even higher in pups exposed to adversity. Finally, PAE reduced KC/GRO and increased IL-10 levels in the amygdala. Our results indicate that PAE alters immune system development and both behavioral and immune responses to early-life adversity, which could have subsequent consequences for brain development and later life health. Copyright © 2017 Elsevier Inc. All rights reserved.

Tekenen en vasseren : Het bedrijf van Jan Peter van Baurscheit (1699 - 1768) en de architectuur in het tweede kwart van de achttiende eeuw

NARCIS (Netherlands)

Breedveldt Boer, I.M.

2003-01-01

Jan Peter van Baurscheit the Younger (1699 - 1768) was educated to become a sculptor and an architect in the studio of his father, J.P. van Baurscheit the elder (1669 - 1728), who owned one of the leading sculptor studios in Antwerpen. Van Baurscheit continued the bussiness after his father's death

A comparison between averaged spikes and individual visually-analyzed spikes in rolandic epileptiform discharges Comparação por análise visual entre as espículas promediadas e as espículas individuais nas descargas epileptiformes rolândicas

Directory of Open Access Journals (Sweden)

Nadia I.O. Braga

2002-09-01

Full Text Available PURPOSE:This study compared some morphological features of individual rolandic epileptiform discharges, used to obtain an averaged estimate, with those of the resulting estimate. METHOD: Twenty-four averaged discharges from EEGs of 24 children showing rolandic spikes were compared with 480 individual discharges used in the averaging. The analysis was based on the occurrence of tangential dipole and "double spike" patterns. RESULTS: In 15 averaged discharges the tangential dipole pattern was found. Individual spikes used in the averaging process displayed the same pattern in 35-100% of them; in the remaining 9 averaged discharges, up to 20% of the individual spikes showed the same pattern, although this was not found in the averaged waveforms. "Double spike" pattern was found in 11 of the averaged waveforms and was recognized in 50-100% of its individual discharges, whereas up to 45% of individual spikes showed this pattern without expression in the averaged waveform. CONCLUSION: When visually analyzing an EEG with rolandic spikes, caution should be exercised in characterizing these patterns, since a few discharges showing them may not be expressed in the averaged waveform and the clinical correlations proposed for these patterns may not apply.OBJETIVO: Comparar as características morfológicas das descargas epileptiformes rolândicas individuais usadas para se obter uma descarga promediada com a resultante promediada. MÉTODO: Vinte e quatro descargas promediadas dos EEG de 24 crianças com descargas epileptiformes rolândicas foram comparadas com as 480 descargas individuais utilizadas na promediação. A análise foi baseada na ocorrência de dipolo tangencial e "dupla espícula". RESULTADOS: Em 15 descargas promediadas o dipolo tangencial estava presente. As espículas individuais usadas na promediação mostraram o mesmo padrão em 35-100% das descargas. Nas 9 descargas promediadas restantes, até 20% das descargas individuais apresentavam

Elucidating adsorption mechanisms of phthalate esters upon carbon nanotubes/graphene and natural organic acid competitive effects in water by DFT and MD calculations

Energy Technology Data Exchange (ETDEWEB)

Wang, Zhuang; Wang, Se; Chen, Min Dong; Xu, Defu [Collaborative Innovation Center of Atmospheric Environment and Equipment Technology, Jiangsu KeyLaboratory of Atmospheric Environment Monitoring and Pollution Control (AEMPC), School ofEnvironmental Science and Engineering, Nanjing University of Information Science and Technology, Nanjing (China); Tang, Lili [Jiangsu Environmental Monitoring Centre, Nanjing (China); Wang, Degao [Dept. of Environmental Science and Engineering, Dalian Maritime University, Dalian (China)

2015-06-15

Simulations at multiple levels were performed to investigate the aqueous adsorption of phthalate esters (PAEs) on carbon nanoparticles and to find the competitive effect of a low molecular weight natural organic acid (benzoic acid) on the adsorption process. Six PAEs of varying alkyl side chain lengths and three carbon-based nanomaterials including a single-walled carbon nanotube (SWNT), double-walled carbon nanotube (DWNT), and graphene (G) were studied. Results showed that the adsorption energies calculated using density functional theory increase with increasing length of the PAE alkyl chain. G exhibits higher adsorption capacity for the PAEs than SWNT and DWNT. The absolute adsorption energies of these systems also display a positive linear correlation with the hydrophobicity of the PAE molecules. Molecular dynamics simulations indicate that the presence of neutral/anionic benzoic acid in water alleviates the PAE adsorption. Furthermore, anionic benzoic acid exerts more impact on the PAE adsorption than the neutral form.

The economics of particulate pollution abatement technologies for wood-waste-fired combustors

International Nuclear Information System (INIS)

Ismail, A.; Stevenson, D.H.

1991-07-01

A study was conducted to quantify the impact of new and improved particulate abatement equipment (PAE) on the economics of new and existing wood waste combustion systems. The operating characteristics of current PAE technology are summarized and the basis for cost estimates is established. The technologies include multicyclone collectors, wet scrubbers, fabric filter baghouses, electrostatic precipitators, and new versus retrofit installations. Capital costs were determined for 4 generic types of PAE and 4 cases for each PAE type according to GJ/h in steam enthalpy. Cost information was developed for wood waste energy systems with and without PAE. In the cost analysis, a hypothetical steam selling price is determined which will give a 25% return on pretax cash flow over a 20-year period. Additional costs of the PAE are applied to the energy system cash flows and the impact on average annual return is calculated. Results indicate reductions in internal rate of return of 3-6% for most PAE systems. 54 refs., 2 figs., 12 tabs

Soil contamination by phthalate esters in Chinese intensive vegetable production systems with different modes of use of plastic film.

Science.gov (United States)

Wang, Jun; Luo, Yongming; Teng, Ying; Ma, Wenting; Christie, Peter; Li, Zhengao

2013-09-01

The concentrations of six priority phthalic acid esters (PAEs) in intensively managed suburban vegetable soils in Nanjing, east China, were analyzed using gas chromatography-mass spectrometry (GC-MS). The total PAE concentrations in the soils ranged widely from 0.15 to 9.68 mg kg(-1) with a median value of 1.70 mg kg(-1), and di-n-butyl phthalate (DnBP), bis-(2-ethylhexyl) phthalate (DEHP) and di-n-octyl phthalate (DnOP) were the most abundant phthalate esters. Soil PAE concentrations depended on the mode of use of plastic film in which PAEs were incorporated as plasticizing agents and both the plastic film and poultry manure appeared to be important sources of soil PAEs. Vegetables in rotation with flooded rice led to lower concentrations of PAEs in soil. The results indicate that agricultural plastic film can be an important source of soil PAE contamination and further research is required to fully elucidate the mechanisms of PAE contamination of intensive agricultural soils with different use modes of use of plastic film. Crown Copyright © 2013. Published by Elsevier Ltd. All rights reserved.

Effects of Persea americana Mill (Lauraceae) ["Avocado"] ethanolic leaf extract on blood glucose and kidney function in streptozotocin-induced diabetic rats and on kidney cell lines of the proximal (LLCPK1) and distal tubules (MDBK).

Science.gov (United States)

Gondwe, M; Kamadyaapa, D R; Tufts, M A; Chuturgoon, A A; Ojewole, J A O; Musabayane, C T

2008-01-01

Extracts of Persea americana Mill (Lauraceae) ("Avocado") have been traditionally used to treat hypertension and diabetes mellitus. Accordingly, we studied the hypoglycaemic and renal function effects of P. americana leaf ethanolic extracts (PAE) in STZ-induced diabetic rats. Oral glucose tolerance responses to various doses of PAE were monitored in fasted rats following a glucose load. Rats treated with deionized water or standard hypoglycaemic drugs acted as untreated and treated positive controls, respectively. Acute renal effects of PAE were investigated in anesthetized rats challenged with 0.077 M NaCl after a 3.5-h equilibration for 4 h comprising 1 h control, 1.5 h treatment and 1.5 h recovery periods. PAE was added to the infusate during the treatment period. Hepatic glycogen concentration was measured after 6 weeks of daily treatment with PAE. PAE induced dose-dependent hypoglycaemic responses in STZ-induced diabetic rats while subchronic PAE treatment additionally increased hepatic glycogen concentrations. Acute PAE infusion decreased urine flow and electrolyte excretion rates, whilst subchronic treatment reduced plasma creatinine and urea concentrations. These results indicate not only the basis of the ethnomedicinal use of P. americana leaf extract in diabetes management, but also of need for further studies to identify and evaluate the safety of PAE's bioactive compounds. (c) 2008 Prous Science, S.A.U. or its licensors. All rights reserved.

Recurrence of Lower Urinary Tract Symptoms Following Prostate Artery Embolization for Benign Hyperplasia: Single Center Experience Comparing Two Techniques

Energy Technology Data Exchange (ETDEWEB)

Carnevale, Francisco Cesar, E-mail: francisco.carnevale@criep.com.br; Moreira, Airton Mota [University of Sao Paulo, Department of Radiology (Brazil); Harward, Sardis Honoria [The Dartmouth Institute for Health Policy and Clinical Practice (United States); Bhatia, Shivank [University of Miami Medical Center, Department of Interventional Radiology (United States); Assis, Andre Moreira de [University of Sao Paulo, Department of Radiology (Brazil); Srougi, Miguel [University of Sao Paulo, Department of Urology (Brazil); Cerri, Giovanni Guido [University of Sao Paulo, Department of Radiology (Brazil); Antunes, Alberto Azoubel [University of Sao Paulo, Department of Urology (Brazil)

2017-03-15

PurposeTo compare recurrence of lower urinary tract symptoms (LUTS) recurrence at 12 months following original prostate artery embolization (oPAE) or “proximal embolization first, then embolize distal” (PErFecTED) PAE for benign prostatic hyperplasia (BPH).Materials and Methods105 consecutive patients older than 45 years, with prostate size greater than 30 cm{sup 3}, International Prostate Symptom Score (IPSS) ≥ 8, quality of life (QoL) index ≥ 3, and refractory status or intolerance of medical management were prospectively enrolled between June 2008 and August 2013. The study was IRB-approved, and all patients provided informed consent. Patients underwent oPAE or PErFecTED PAE and were followed for at least 12 months. Technical success was defined as bilateral embolization and clinical success (non-recurrence) was defined as removal of the Foley catheter in patients with urinary retention, IPSS < 8 and QoL index < 3 at 12 months of follow-up. Nonparametric statistics were used to compare the study groups due to the size of the study population and distributions of clinical data.Results97 patients had 12-month data and were categorized as oPAE without recurrence (n = 46), oPAE with recurrence (n  = 13), PErFecTED without recurrence (n  = 36), or PErFecTED with recurrence (n  = 2). Recurrence was significantly more common in oPAE patients (χ{sup 2}, p = 0.026). Unilateral embolization was significantly associated with recurrence among patients who underwent oPAE (χ{sup 2}, p = 0.032).ConclusionsBoth oPAE and PErFecTED PAE are safe and effective methods for treatment of LUTS, but PErFecTED PAE is associated with a significantly lower rate of symptom recurrence.

Eesti arhitektuur trügis maailmakaardile / Tiina Kolk

Index Scriptorium Estoniae

Kolk, Tiina

2004-01-01

Neli eesti arhitektide projekteeritud hoonet on pääsenud kunstikirjastuse Phaidon raamatusse "The Phaidon Atlas of Contemporary World Architecture": Indrek Allmanni paariselamu Luccas, Martin Aunini eramu Orro Tabasalus, Indrek Näki Neiseri tööstushoone ja büroo 3+1 arhitektide Villa V. 3+1 arhitektid Markus Kaasik, Andres Ojari, Ilmar Valdur ja Inga Raukas esindavad ka Leedumaad Eesti saatkonnahoonega Vilniuses. 4 ill

Vojtěch Jirát a Jan Mukařovský aneb Příběh jedné nevydané recenze

Czech Academy of Sciences Publication Activity Database

Sládek, Ondřej

2011-01-01

Roč. 59, č. 2 (2011), s. 219-231 ISSN 0009-0468 R&D Projects: GA ČR GAP406/10/1911 Institutional research plan: CEZ:AV0Z90560517 Keywords : Czech structuralism * Mukařovský, Jan * Jirát, Vojtěch * Mácha, Karel Hynek Subject RIV: AJ - Letters, Mass-media, Audiovision

The effects of petroleum activity in the Northern areas. Northern Sea, Jan Mayen and the Barents sea; Ringvirkninger av petroleumsaktivitet i nordomraader. Norskehavet, Jan Mayen og Barentshavet

Energy Technology Data Exchange (ETDEWEB)

Eika, Torbjoern; Prestmo, Joakim; Cappelen, Aadne

2012-11-15

The effects of petroleum activity respectively in the north-eastern Norwegian Sea,Barents Sea south-east and around Jan Mayen are not likely to be very large in a national context, but clearly noticeable. The calculations show the effects of activity in the relevant area, compared to a situation where this activity is not initiated. This can be considered as a study of how the Norwegian economy is affected by a decision to start exploration, followed by developing of the economically viable discoveries. Fiscal policy is assumed unaffected. It is thus not taken into account how the different scenarios will affect the pension fund and thus the frames for oil spending resulting from the fiscal rule. The effects we study are the direct employment in the petroleum sector that can be expected, and the effects of the demand in the form of capital goods and intermediate input. Uncertainty is discussed for each area in terms of alternative scenarios of relatively high and relatively low quantities of petroleum resources. The impact on the economy is clearly most significant in the development phase. This is because the demand related to exploration and operation phases are much more modest. The effects during the production phase are dampened by the weakened cost competitiveness as results of higher level of activity in previous phases. In scenarios with modest demand and petroleum production, employment may at some point of time even be lower than a scenario without increased petroleum activity. In the two scenarios with low and high levels of petroleum activity in the northeastern Norwegian Sea, total annual employment in Norway increases by respectively 3 000 and 10 000 persons at the most. On average for the period 2014-2045, the increase is 800 persons with a low level of activity and 2 300 persons with a high activity level. GDP excluding recovery will in the period 2014-2045, on average, increase by respectively 1.5 and 5.3 billion 2009 million annually in the two

Efficacy and safety of prostate artery embolization for benign prostatic hyperplasia: an observational study and propensity-matched comparison with transurethral resection of the prostate (the UK-ROPE study).

Science.gov (United States)

Ray, Alistair F; Powell, John; Speakman, Mark J; Longford, Nicholas T; DasGupta, Ranan; Bryant, Timothy; Modi, Sachin; Dyer, Jonathan; Harris, Mark; Carolan-Rees, Grace; Hacking, Nigel

2018-04-12

To assess the efficacy and safety of prostate artery embolization (PAE) for lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH) and to conduct an indirect comparison of PAE with transurethral resection of the prostate (TURP). As a joint initiative between the British Society of Interventional Radiologists, the British Association of Urological Surgeons and the National Institute for Health and Care Excellence, we conducted the UK Register of Prostate Embolization (UK-ROPE) study, which recruited 305 patients across 17 UK urological/interventional radiology centres, 216 of whom underwent PAE and 89 of whom underwent TURP. The primary outcomes were International Prostate Symptom Score (IPSS) improvement in the PAE group at 12 months post-procedure, and complication data post-PAE. We also aimed to compare IPSS score improvements between the PAE and TURP groups, using non-inferiority analysis on propensity-score-matched patient pairs. The clinical results and urological measurements were performed at clinical sites. IPSS and other questionnaire-based results were mailed by patients directly to the trial unit managing the study. All data were uploaded centrally to the UK-ROPE study database. The results showed that PAE was clinically effective, producing a median 10-point IPSS improvement from baseline at 12 months post-procedure. PAE did not appear to be as effective as TURP, which produced a median 15-point IPSS score improvement at 12 months post-procedure. These findings are further supported by the propensity score analysis, in which we formed 65 closely matched pairs of patients who underwent PAE and patients who underwent TURP. In terms of IPSS and quality-of-life (QoL) improvement, there was no evidence of PAE being non-inferior to TURP. Patients in the PAE group had a statistically significant improvement in maximum urinary flow rate and prostate volume reduction at 12 months post-procedure. PAE had a reoperation rate of 5

Drought-breaking love: An analysis of the moral values implied in ‘Drought’ by Jan Rabie

Directory of Open Access Journals (Sweden)

C. N. van der Merwe

1996-04-01

Full Text Available In this article the tension in 20th century literary theory between absolutism and relativism is discussed. It is argued that, in spite of a movement from absolutism towards relativism, the age-old “absolute” values of truth, beauty and goodness have never been totally forsaken in the creation and the contemplation of literature. In an analysis of “Drought” by Jan Rabie, it is indicated how these values are implied and invoked in Rabie's short story. In conclusion, the fundamental value of love or charity is discussed, a value which contains and supersedes the values of truth, beauty and goodness, and reconciles the tension between absolutism and relativism.

A critical review of Jan Beyea's report: A study of some of the consequences of hypothetical reactor accidents at Barsebaeck

International Nuclear Information System (INIS)

Gjoerup, H.L.; Hedemann Jensen, P.; Jensen, N.O.; Pejtersen, V.; Lundtang Petersen, E.; Petersen, T.; Thykier-Nielsen, S.; Heikel Vinther, F.

1978-04-01

This report contains a critical review of Jan Beyea's report: A study of some of the consequences of hypothetical reactor accidents at Barsebaeck (Princeton University, January 1978). Unreasonable assumptions concerning dry deposition, plume rise, meteorological considerations, dose-response relationship and probability distributions were found in the report. It is found that the conclusions of the Beyea report are the result of a mathematical exercise rather than the results of a realistic risk evaluation for Barsebaeck. (author)

Tark disain = Intelligent Design / Inga Raukas

Index Scriptorium Estoniae

Raukas, Inga, 1967-

2006-01-01

Ökoloogilisest arhitektuurist, disainist, käitumisest ja suhtumisest. Ill.: Arhitektuuriagentuuri planeeringu eskiisprojekt Harku järve äärde, Mustamäe planeeringu ideeprojekt, projekt 0001: kasvav maja, Tarmo Teedumäe ökomaja Hiiumaale. Bibliograafia lk. 7

Tark urbanism = Smart urbanism / Inga Raukas

Index Scriptorium Estoniae

Raukas, Inga, 1967-

2008-01-01

Tallinna Ülemiste City kvartalist, mille projekteerijad on Mattias Agabus, Eero Endjärv, Illimar Truverk, hoonete arhitektuurse osa autor E. Endjärv, sisearhitektid Kristi Lents, Hannelore Kääramees ja Taavi Aunre (restoran Mercado), maastikuarhitektid Ülle Grišakov, M. Agabus, E. Endjärv. Projekt 2006, valmis 2008 (1. ehitusetapp)

Fine motor skills in children with prenatal alcohol exposure or fetal alcohol spectrum disorder.

Science.gov (United States)

Doney, Robyn; Lucas, Barbara R; Jones, Taryn; Howat, Peter; Sauer, Kay; Elliott, Elizabeth J

2014-01-01

Prenatal alcohol exposure (PAE) can cause fetal alcohol spectrum disorders (FASD) and associated neurodevelopmental impairments. It is uncertain which types of fine motor skills are most likely to be affected after PAE or which assessment tools are most appropriate to use in FASD diagnostic assessments. This systematic review examined which types of fine motor skills are impaired in children with PAE or FASD; which fine motor assessments are appropriate for FASD diagnosis; and whether fine motor impairments are evident at both "low" and "high" PAE levels. A systematic review of relevant databases was undertaken using key terms. Relevant studies were extracted using a standardized form, and methodological quality was rated using a critical appraisal tool. Twenty-four studies met inclusion criteria. Complex fine motor skills, such as visual-motor integration, were more frequently impaired than basic fine motor skills, such as grip strength. Assessment tools that specifically assessed fine motor skills more consistently identified impairments than those which assessed fine motor skills as part of a generalized neurodevelopmental assessment. Fine motor impairments were associated with "moderate" to "high" PAE levels. Few studies reported fine motor skills of children with "low" PAE levels, so the effect of lower PAE levels on fine motor skills remains uncertain. Comprehensive assessment of a range of fine motor skills in children with PAE is important to ensure an accurate FASD diagnosis and develop appropriate therapeutic interventions for children with PAE-related fine motor impairments.

Soil contamination by phthalate esters in Chinese intensive vegetable production systems with different modes of use of plastic film

International Nuclear Information System (INIS)

Wang, Jun; Luo, Yongming; Teng, Ying; Ma, Wenting; Christie, Peter; Li, Zhengao

2013-01-01

The concentrations of six priority phthalic acid esters (PAEs) in intensively managed suburban vegetable soils in Nanjing, east China, were analyzed using gas chromatography–mass spectrometry (GC–MS). The total PAE concentrations in the soils ranged widely from 0.15 to 9.68 mg kg −1 with a median value of 1.70 mg kg −1 , and di-n-butyl phthalate (DnBP), bis-(2-ethylhexyl) phthalate (DEHP) and di-n-octyl phthalate (DnOP) were the most abundant phthalate esters. Soil PAE concentrations depended on the mode of use of plastic film in which PAEs were incorporated as plasticizing agents and both the plastic film and poultry manure appeared to be important sources of soil PAEs. Vegetables in rotation with flooded rice led to lower concentrations of PAEs in soil. The results indicate that agricultural plastic film can be an important source of soil PAE contamination and further research is required to fully elucidate the mechanisms of PAE contamination of intensive agricultural soils with different use modes of use of plastic film. -- Highlights: •Phthalate esters in soils from suburban intensive vegetable production systems were investigated. •Phthalate levels and risks of the vegetable soils with different plastic film use modes were examined. •Sources of phthalate esters in vegetable production soils were analyzed. -- PAE contamination of intensively managed vegetable soils varied widely depending on the mode of use of plastic film in different production systems

Occurrence and Removal Characteristics of Phthalate Esters from Typical Water Sources in Northeast China

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Yu Liu

2013-01-01

Full Text Available The presence of phthalate esters (PAEs in the environment has gained a considerable attention due to their potential impacts on public health. This study reports the first data on the occurrence of 15 PAEs in the water near the Mopanshan Reservoir—the new and important water source of Harbin city in Northeast China. As drinking water is a major source for human exposure to PAEs, the fate of target PAEs in the two waterworks (Mopanshan Waterworks and Seven Waterworks was also analyzed. The results demonstrated that the total concentrations of 15 PAEs in the water near the Mopanshan Reservoir were relatively moderate, ranging from 355.8 to 9226.5 ng/L, with the mean value of 2943.1 ng/L. DBP and DEHP dominated the PAE concentrations, which ranged from 52.5 to 4498.2 ng/L and 128.9 to 6570.9 ng/L, respectively. The occurrence and concentrations of these compounds were heavily spatially dependent. Meanwhile, the results on the waterworks samples suggested no significant differences in PAE levels with the input of the raw waters. Without effective and stable removal of PAEs after the conventional drinking water treatment in the waterworks (25.8% to 76.5%, the risks posed by PAEs through drinking water ingestion were still existing, which should be paid special attention to the source control in the Mopanshan Reservoir and some advanced treatment processes for drinking water supplies.

Reliable quantification of phthalates in environmental matrices (air, water, sludge, sediment and soil): a review.

Science.gov (United States)

Net, Sopheak; Delmont, Anne; Sempéré, Richard; Paluselli, Andrea; Ouddane, Baghdad

2015-05-15

Because of their widespread application, phthalates or phthalic acid esters (PAEs) are ubiquitous in the environment. Their presence has attracted considerable attention due to their potential impacts on ecosystem functioning and on public health, so their quantification has become a necessity. Various extraction procedures as well as gas/liquid chromatography and mass spectrometry detection techniques are found as suitable for reliable detection of such compounds. However, PAEs are ubiquitous in the laboratory environment including ambient air, reagents, sampling equipment, and various analytical devices, that induces difficult analysis of real samples with a low PAE background. Therefore, accurate PAE analysis in environmental matrices is a challenging task. This paper reviews the extensive literature data on the techniques for PAE quantification in natural media. Sampling, sample extraction/pretreatment and detection for quantifying PAEs in different environmental matrices (air, water, sludge, sediment and soil) have been reviewed and compared. The concept of "green analytical chemistry" for PAE determination is also discussed. Moreover useful information about the material preparation and the procedures of quality control and quality assurance are presented to overcome the problem of sample contamination and these encountered due to matrix effects in order to avoid overestimating PAE concentrations in the environment. Copyright © 2015 Elsevier B.V. All rights reserved.

Thermal and enzymatic pretreatment of sludge containing phthalate esters prior to mesophilic anaerobic digestion

DEFF Research Database (Denmark)

Gavala, Hariklia N.; Yenal, U.; Ahring, Birgitte Kiær

2004-01-01

The present study aimed at investigating the effect of thermal pretreatment of sludge at 70degreesC on the anaerobic degradation of three commonly found phthalic acid esters (PAE): di-ethyl phthalate (DEP), di-butyl phthalate (DBP), and di-ethylhexyl phthalate (DEHP). Also, the enzymatic treatment...... at 28degreesC with a commercial lipase was studied as a way to enhance PAE removal. Pretreatment at 70degreesC of the sludge containing PAE negatively influenced the anaerobic biodegradability of phthalate esters at 37degreesC. The observed reduction of PAE biodegradation rates after the thermal...... pretreatment was found to be proportional to the PAE solubility in water: the higher the solubility, the higher the percentage of the reduction (DEP > DBP > DEHP). PAE were slowly degraded during the pretreatment at 70degreesC, yet this was probably due to physicochemical reactions than to microbial...

Cognitive and behavioral comorbidities in Rolandic epilepsy and their relation with default mode network's functional connectivity and organization.

Science.gov (United States)

Ofer, Isabell; Jacobs, Julia; Jaiser, Nathalie; Akin, Burak; Hennig, Jürgen; Schulze-Bonhage, Andreas; LeVan, Pierre

2018-01-01

Rolandic epilepsy (RE) is characterized by typical interictal-electroencephalogram (EEG) patterns mainly localized in centrotemporal and parietooccipital areas. An aberrant intrinsic organization of the default mode network (DMN) due to repeated disturbances from spike-generating areas may be able to account for specific cognitive deficits and behavioral problems in RE. The aim of the present study was to investigate cognitive development (CD) and socioemotional development (SED) in patients with RE during active disease in relation to DMN connectivity and network topology. In 10 children with RE and active EEG, CD was assessed using the Wechsler Intelligence Scale for Children-IV (WISC-IV); SED was assessed using the Fünf-Faktoren-Fragebogen für Kinder (FFFK), a Big-Five inventory for the assessment of personality traits in children. Functional connectivity (FC) in the DMN was determined from a 15-minute resting state functional magnetic resonance imaging (fMRI), and network properties were calculated using standard graph-theoretical measures. More severe deficits of verbal abilities tended to be associated with an earlier age at epilepsy onset, but were not directly related to the number of seizures and disease duration. Nonetheless, at the network level, disease duration was associated with alterations of the efficiency and centrality of parietal network nodes and midline structures. Particularly, centrality of the left inferior parietal lobe (IPL) was found to be linked with CD. Reduced centrality of the left IPL and alterations supporting a rather segregated processing within DMN's subsystems was associated with a more favorable CD. A more complicated SED was associated with high seizure frequency and long disease duration, and revealed links with a less favorable CD. An impaired CD and - because of their interrelation - SED might be mediated by a common pathomechanism reflected in an aberrant organization, and thus, a potential functional deficit of the DMN

Kolmas aed = The Third Garden / Martin Melioranski

Index Scriptorium Estoniae

Melioranski, Martin

2006-01-01

Aed ja eramu Meriväljal Viimsi ja Väina tee nurgal. Projekt: Arhitektuuriagentuur. Autorid: Inga Raukas, Toomas Tammis, Tarmo Teedumäe. Haljastuse konsultant Signe Peipman. Projekt 2005, valmis 2006. Aed ja eramu Naeri tänaval. Projekt: Kolm Pluss Üks Arhitektid. Autorid: Markus Kaasik, Andres Ojari, Ilmar Valdur, Merje Müürsepp, Kalle Komissarov (2002). Projekt 2002-2004, valmis 2005. Ill.: kaks plaani, 6 värv. vaadet

Ehitaja Aastaehitised 2003 on selgunud

Index Scriptorium Estoniae

2004-01-01

Aastaehitised 2003: uusehitis - Laulasmaa SPA & Konverentsihotell (arhitekt Priit Ehala, AB Ehala & Irik, projekteerija Projektbüroo Teinos, ehitaja FKSM), renoveeritud ehitis - korterelamu Tallinnas Piiskopi t. 2 (arhitekt Elmo Raukas, sisearhitekt Heli Eensalu, projektterija ja ehitaja Restor), rajatis - Turu sild Tartus (arhitektuurne lahendus: Tartu Arhitektuuribüroo, vantsüsteemide arvutused: Ehituse & Tarkvara Inseneribüroo), eramu - Merirahu eramu (arhitekt Tarmo Piirmets, projekteerija Estkonsult, ehitaja E-Betoonelement). 4 ill

Popliteal Artery Entrapment Syndrome in Children: Experience With Four Cases of Acute Ischaemia and Review of the Literature.

Science.gov (United States)

Settembre, N; Bouziane, Z; Bartoli, M A; Nabokov, V; Venermo, M; Feugier, P; Malikov, S

2017-04-01

Popliteal artery entrapment syndrome (PAES) is an uncommon anatomical anomaly, frequently described in adults. The most common symptom is claudication. Acute limb ischaemia (ALI) in children is rare, but it may evolve and lead to limb loss or lifelong complications. Clinical and surgical experience of PAES in children is reported. Data from the literature are analysed in order to assess the severity of this disease and to identify the factors characterising the diagnosis and the outcome of treatment in paediatric patients. Four children (aged 7-16 years) were referred with ALI due to PAES. Among the 439 articles reporting cases of PAES, 55 patients under 18 years of age were the focus. The PAES cases were classified according to the Love and Whelan classification modified by Rich. Data from 79 children (106 limbs, 27 bilateral PAES) were collected and analysed. Type I PAES was present in 41 (39%), Type II in 23 (22%), Type III in 24 (23%), Type IV in 12 (11%), and Type V in two (2%) limbs. A functional PAES was present in one patient bilaterally. In two cases, the type of PAES was not reported. Claudication occurred in 68 cases (64%), and ALI in 19 (18%). In 60 cases (57%), revascularisation with or without myotomy was required; myotomy alone was performed in 41 cases (39%). Symptomatic PAES in children should be considered a severe condition requiring urgent investigation in order to avoid any delays in the treatment. Early diagnosis and treatment are essential to prevent serious complications. The long-term outcomes of surgical treatment with the correction of the anatomical anomaly and vascular reconstruction are satisfactory with a low complication rate. Copyright © 2017 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.

Alcohol expectancies, perceived norms, and drinking behavior among college students: examining the reciprocal determinism hypothesis.

Science.gov (United States)

Wardell, Jeffrey D; Read, Jennifer P

2013-03-01

Social learning mechanisms, such as descriptive norms for drinking behavior (norms) and positive alcohol expectancies (PAEs), play a major role in college student alcohol use. According to the principle of reciprocal determinism (Bandura, 1977), norms and PAEs should be reciprocally associated with alcohol use, each influencing one another over time. However, the nature of these prospective relationships for college students is in need of further investigation. This study provided the first examination of the unique reciprocal associations among norms, PAEs, and drinking together in a single model. PAEs become more stable with age, whereas norms are likely to be more dynamic upon college entry. Thus, we hypothesized that alcohol use would show stronger reciprocal associations with norms than with PAEs for college students. Students (N = 557; 67% women) completed online measures of PAEs, norms, and quantity and frequency of alcohol use in September of their first (T1), second (T2), and third (T3) years of college. Reciprocal associations were analyzed using a cross-lagged panel design. PAEs had unidirectional influences on frequency and quantity of alcohol use, with no prospective effects from alcohol use to PAEs. Reciprocal associations were observed between norms and alcohol use, but only for quantity and not for frequency. Specifically, drinking quantity prospectively predicted quantity norms and quantity norms prospectively predicted drinking quantity. This effect was observed across both years in the model. These findings support the reciprocal determinism hypothesis for norms but not for PAEs in college students and may help to inform norm-based interventions. (PsycINFO Database Record (c) 2013 APA, all rights reserved).

Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.

Science.gov (United States)

Gong, Xiaobao; Yang, You; Huang, Ligua; Zhang, Qingyan; Wan, Rong-Zhen; Zhang, Peng; Zhang, Baoshun

2017-05-01

To evaluate the hepatoprotective effects and potential mechanisms of paeonol (Pae) against acute liver failure (ALF) induced by lipopolysaccharide (LPS)/d-galactosamine (d-GalN) in mice, we examined anti-oxidative, anti-inflammatory and anti-apoptotic activities of Pae. We found that Pae pretreatment markedly reduced the activities of alanine transaminase and aspartate transaminase as well as the histopathological changes induced by LPS/d-GalN. Catalase, glutathione and superoxide dismutase activities increased and reactive oxygen species activity decreased after Pae treatment compared with LPS/d-GalN treatment. Pretreatment with Pae also significantly inhibited the expression levels of iNOS, nitric oxide (NO), COX-2 and prostaglandin E 2 (PGE 2 ). In addition, Pae administration prevented the phosphorylated expression of IκB kinase, inhibitor kappa B in the nuclear factor-kappa B (NF-κB) signaling pathway, and suppressed the phosphorylated expression of extracellular signal-regulated kinase (ERK), c-jun-N-terminal kinase and p38 in the MAPK signaling pathway. Pretreatment with Pae also inhibited hepatocyte apoptosis by reducing the expression of caspases 3, 8, 9, and Bax, and increasing Bcl-2. In total, protective effects of Pae against LPS/d-GalN-induced ALF in mice are attributed to its antioxidative effect, inflammatory suppression in NF-κB and MARK signaling pathways, and inhibition of hepatocyte apoptosis inhibition. Therefore, Pae can be a potential therapeutic agent in attenuating LPS/d-GalN-induced ALF in the future. Copyright © 2017. Published by Elsevier B.V.

Application of positron annihilation induced auger electron spectroscopy to the study of surface chemistry

International Nuclear Information System (INIS)

Weiss, A.H.; Yang, G.; Nangia, A.; Kim, J.H.; Fazleev, N.G.

1996-01-01

Positron annihilation induced Auger Electron Spectroscopy (PAES), makes use a beam of low energy positrons to excite Auger transitions by annihilating core electrons. This novel mechanism provides PAES with a number of unique features which distinguishes it from other methods of surface analysis. In PAES the very large collisionally induced secondary electron background which is present under the low energy Auger peaks using conventional techniques can be eliminated by using a positron beam whose energy is below the range of Auger electron energies. In addition, PAES is more surface selective than conventional Auger Spectroscopy because the PAES signal originates almost exclusively from the topmost atomic layer due to the fact that the positrons annihilating with the core electrons are trapped in an image correlation well just outside the surface. In this paper, recent applications of Positron Annihilation Induced Auger Electron Spectroscopy (PAES) to the study of surface structure and surface chemistry will be discussed including studies of the growth, alloying and inter-diffusion of ultrathin layers of metals, metals on semiconductors, and semiconductors on semiconductors. In addition, the possibilities for future application of PAES to the study of catalysis and surface chemistry will be outlined. (author)

Jan Fook: Social Work: Critical Theory and Practice & Karen Healy: Social Work Practices: Contemporary Perspectives on Change

Directory of Open Access Journals (Sweden)

2003-11-01

Full Text Available In his recent book on the contemporary politics of social work, Powell (2001 nominates Jan Fook and Karen Healy as two Australian authors who have made significant contributions to the radical or critical social work tradition. I have chosen to review them together, as each, in different ways, attempts to achieve the same purpose. That is, they attempt to provide a convincing account for adopting a critical approach to practice in the contemporary conditions of the 21st century and, in doing so, re-invigorate the radical tradition of social work practice. My first comment, important for the readership of this international journal, is that both books easily 'travel' beyond the Australian context.

Phthalate esters and organochlorine pesticides in agricultural soils and vegetables from fast-growing regions: a case study from eastern China.

Science.gov (United States)

Sun, Jianteng; Pan, Lili; Tsang, Daniel C W; Li, Zhiheng; Zhu, Lizhong; Li, Xiangdong

2018-01-01

The present study investigated phthalate esters (PAEs) and organochlorine pesticides (OCPs) in agricultural soils and vegetables from eastern China. The concentrations of PAEs ranged from 109 to 5560 ng/g in soils and 60.1 to 2390 ng/g in cabbages, with average concentrations of 946 and 601 ng/g, respectively. The concentrations of OCPs ranged from usage, whereas building materials and agricultural plastic film were possible input sources of PAEs in the ambient environment. OCPs showed no apparent effect on soil microbial communities, whereas significant negative relationship was observed between PAEs and fungi in soils (R = -0.54, p < 0.01). Human health risk assessment data revealed marginal noncarcinogenic risks and low carcinogenic risks in these soils. Notably, PAEs posed a comparable or higher risk level compared with that of OCPs. This study suggests the need for better regulation on pollution control and management of PAE-elevated sites to protect soil quality and food safety.

Cambodian and their Doctors, a Medical Anthropology of Colonial and Post-Colonial Cambodia, Jan Ovesen & Ing-Britt Trankell

Directory of Open Access Journals (Sweden)

Didier Bertrand

2012-09-01

Full Text Available Cet ouvrage, écrit par Jan Ovesen et Ing-Britt Trankell (professeurs associés d’anthropologie à l’université d’Uppsala engagés dans l’étude de la société cambodgienne depuis 1995, offre une synthèse unique d’anthropologie historique et d’ethnographie contemporaine sur le système de soins de santé cambodgien de la colonisation française à nos jours. Les auteurs décrivent la tension dans le Cambodge moderne entre la tradition médicale occidentale introduite par les colonisateurs français et le...

Paleosecular variation analysis of high-latitude paleomagnetic data from the volcanic island of Jan Mayen

Science.gov (United States)

Cromwell, G.; Tauxe, L.; Staudigel, H.; Pedersen, L. R.; Constable, C.; Pedersen, R.; Duncan, R. A.; Staudigel, P.

2009-12-01

Recent investigation of high-latitude paleomagnetic data from the Erebus Volcanic Province (EVP), Antarctica shows a departure from magnetic dipole predictions for paleointensity data for the period 0-5 Ma. The average EVP paleointensity (31.5 +/- 2.4 μT) is equivalent to low-latitude measurements (1) or approximately half the strength predicted for a dipole at high-latitude. Also, paleosecular variation models (e.g., 2,3) predict dispersions of directions that are much lower than the high latitude observations. Observed low intensity values may be the result of reduced convective flow inside the tangent cylinder of the Earth’s core or insufficient temporal sampling (1). More high-latitude paleomagnetic data are necessary in order to investigate the cause of the depressed intensity values and to provide better geographic and temporal resolution for future statistical paleosecular variation models. To address this, we carried out two field seasons, one in Spitzbergen (79°N, 14°E) and one on the young volcanic island of Jan Mayen (71°N, 8°W). The latter sampling effort was guided by age analyses of samples obtained by P. Imsland (unpublished and 4). We will present new paleodirectional and paleointensity data from a total of 25 paleomagnetic sites. These data enhance the temporal resolution of global paleomagnetic data and allow for a more complete evaluation of the time-averaged magnetic field from 0-5 Ma. We will present a new analysis of paleosecular variation based on our new data, in combination with other recently published data sets. (1) Lawrence, K.P., L.Tauxe, H. Staudigel, C.G. Constable, A. Koppers, W. MacIntosh, C.L. Johnson, Paleomagnetic field properties at high southern latitude. Geochemistry Geophysics Geosystems 10 (2009). (2) McElhinny, M.W., P.L. McFadden, Paleosecular variation over the past 5 Myr based on a new generalized database. Geophysics Journal International 131 (1997), 240-252. (3) Tauxe, L., Kent, D.V., A simplified statistical

[Jan Fryderyk Wolfgang's autobiography (1850) in the light of hand-written and printed sources].

Science.gov (United States)

Kuźnicka, B

2001-01-01

The archival collection of the Lithuanian Academy of Sciences in Vilnius (Wilno) contains many manuscripts relating to the scientific work of Jan Fryderyk Wolfgang (1776-1859), professor of pharmacy and pharmacology of the Wilno University in the years 1807-1831, the founder and main figure in the Wilno pharmacognostic school, a botanist with substantial achievements in wide-ranging research on the flora of the Wilno region, as well as a historian of pharmacy. The most interesting of the manuscripts include Wolfgang's Autobiografia [Autobiography], written in 1850, and a list of his publications covering a total of 57 items (including some that have hitherto remained unknown), a work entitled Historya Farmakologii i Farmacyi [History of pharmacology and pharmacy], and a particularly valuable manuscript (666 + 12 sheets) entitled Farmakologiia [Pharmacology]. Worth mentioning are also two catalogues of books from Wolfgang's library: one compiled by Wolfgang himself (37 sheets) and the other by Adam Ferdynand Adamowicz. The content of the autobiography manuscript is contained on five sheets. The author of the present article analyzes the document, comparing the information contained in it with the biographies of J. F. Wolfgang that hhave been published so far (these being primarily the biography by Dominik Cezary ChodYko, published in 1863, and that by Witold W3odzimierz G3owacki of 1960). The text of the autobiography is quoted in full, together with numerous comments. The analysis of the manuscript as well as the biographical data contained in the above-mentioned biographies indicate that Wolfgang had great achievements as a scientist (in both research and organizational work), as a champion of public causes and as an educator of a generation of botanists-pharmacognostics. It also transpires from the autobiography, as well as from the research by historians, that he was a very good and trustful person, who readily granted access to his research to his collaborators

Role of caregiver-reported outcomes in identification of children with prenatal alcohol exposure during the first year of life.

Science.gov (United States)

Bakhireva, Ludmila N; Lowe, Jean; Garrison, Laura M; Cano, Sandra; Leyva, Yuridia; Qeadan, Fares; Stephen, Julia M

2018-05-16

BackgroundEarlier identification of children with prenatal alcohol exposure (PAE) remains a challenge. The objective of this study was to identify neurobehavioral (NB) outcomes associated with PAE in infants.MethodsThis manuscript evaluates NB outcomes at 6.33±1.12 months of age in 93 infants (39 PAE and 54 No-PAE) recruited prospectively into the ENRICH cohort. PAE was assessed by prospective repeated TLFB interviews and a panel of ethanol biomarkers. NB outcomes were evaluated by the Bayley Scales of Infant Development (BSID-III), Parenting Stress Index (PSI), Infant Behavior Questionnaire (IBQ-R), and Infant Sensory Profile (ISP).ResultsMean maternal age at enrollment was 28.18±5.75, and 64.52% were Hispanic/Latina. Across three TLFB calendars, absolute alcohol per day in the PAE group was 0.44±0.72, corresponding to low-moderate alcohol consumption. While no association was observed between PAE and BSID-III (P's>0.05), PAE was associated with higher scores on the PSI difficult child scale (=13.9; P=0.015), total stress (=13.9; P=0.010), and IBQ negative affect (=8.60; P=0.008) measures after adjustment for covariates.ConclusionsCaregiver-reported assessments may provide a currently unrecognized opportunity to identify behavioral deficits, point to early interventions, and should be included in clinical assessments of infants at-risk for fetal alcohol spectrum disorder.Pediatric Research advance online publication, 16 May 2018; doi:10.1038/pr.2018.26.

Valik arvamusi läbi aastate / Ain-Elmar Kaasik

Index Scriptorium Estoniae

Kaasik, Ain-Elmar, 1934-

2008-01-01

Valik Eesti Teaduste Akadeemia Aastaraamatus rubriigis "Arvamusi akadeemikutelt" ilmunud kirjutisi, kus vabas vormis käsitletakse mitmesuguseid aktuaalseid küsimusi, eelkõige hariduse, teadustöö ning ühiskonna suhteid. Kokku on rubriigis avaldatud ligi kaks ja poolsada kirjutist. Siinse valiku autoriteks akadeemikud Raimund Hagelberg, Mart Saarma, Boris Tamm, Ene Ergma, Arvo Krikmann, Agu Laisk, Hans-Voldemar Trass, Harald Keres, Anto Raukas, Rein Küttner, Enn Tõugu, Raimund-Johannes Ubar, Ain-Elmar Kaasik

Archeographical and historical artifact of the Jesuits of Saint Jan collegium in Jaroslav in the late XVII century in the fonds of the Manuscript Institute of VNLU

Directory of Open Access Journals (Sweden)

Bulatova S.

2014-01-01

Full Text Available The publication treats a manuscript inventory of the late XVII century, unknown for historians, which contains the descriptions of landed estates of the Jesuit collegium of Saint Jan in Jaroslav. The paper covers the archeographical aspect of research of the manuscript artifact of Subcarpathian land, which is currently deposited in the fonds of the Manuscript Institute of V. Vernadsky National Library of Ukraine. The author-originator of the manuscript states explicit historical-archival data on Jesuit and szlachta landed estates in Subcarpathian region in XVI-XVII centuries, in particular the possessions of Jaroslav landed holdings. In the publication we consider the historical information on the original sources of various antiquariums and archives of Rich Pospolyta, primarily the archive of the Jesuit collegium in Jaroslav, which are stated in the manuscript inventory. The archeographical analysis of the manuscript, performed in the article, contributes to the historical reconstruction of the Jesuit collegium of Saint Jan in Jaroslav.

Efficacy and possible mechanisms of perillaldehyde in control of Aspergillus niger causing grape decay.

Science.gov (United States)

Tian, Jun; Wang, Yanzhen; Zeng, Hong; Li, Zongyun; Zhang, Peng; Tessema, Akalate; Peng, Xue

2015-06-02

A variety of plant products have been recognized for their antifungal activity and recently have attracted food industry attention for their efficacy in controlling postharvest fungal decay of fruits. The antifungal activity of perillaldehyde (PAE) was evaluated against Aspergillus niger, a known cause of grape spoilage, and possible mechanisms were explored. PAE showed notable antifungal activity against A. niger, with a minimum inhibitory concentration (MIC) and a minimum fungicidal concentration (MFC) of 0.25 and 1 μl/ml, respectively. The accumulation of mycelial biomass was also inhibited by PAE in a dose-dependent manner, completely inhibiting mycelial growth at 1 μl/ml. In vivo data confirmed that the vapour treatment of grapes with various concentrations of PAE markedly improved control of A. niger and suppressed natural decay. Concentrations of PAE of 0.075 μl/ml air showed the greatest inhibition of fungal growth compared to the controls. Further experiments indicated that PAE activated a membrane-active mechanism that inhibits ergosterol synthesis, increases membrane permeability (as evidenced by extracellular pH and conductivity measurements), and disrupts membrane integrity, leading to cell death. Our findings suggest that this membrane-active mechanism makes PAE a promising potential antifungal agent for postharvest control of grape spoilage. Copyright © 2015 Elsevier B.V. All rights reserved.

Skeletal muscle and fetal alcohol spectrum disorder.

Science.gov (United States)

Myrie, Semone B; Pinder, Mark A

2018-04-01

Skeletal muscle is critical for mobility and many metabolic functions integral to survival and long-term health. Alcohol can affect skeletal muscle physiology and metabolism, which will have immediate and long-term consequences on health. While skeletal muscle abnormalities, including morphological, biochemical, and functional impairments, are well-documented in adults that excessively consume alcohol, there is a scarcity of information about the skeletal muscle in the offspring prenatally exposed to alcohol ("prenatal alcohol exposure"; PAE). This minireview examines the available studies addressing skeletal muscle abnormalities due to PAE. Growth restriction, fetal alcohol myopathy, and abnormalities in the neuromuscular system, which contribute to deficits in locomotion, are some direct, immediate consequences of PAE on skeletal muscle morphology and function. Long-term health consequences of PAE-related skeletal abnormalities include impaired glucose metabolism in the skeletal muscle, resulting in glucose intolerance and insulin resistance, leading to an increased risk of type 2 diabetes. In general, there is limited information on the morphological, biochemical, and functional features of skeletal abnormalities in PAE offspring. There is a need to understand how PAE affects muscle growth and function at the cellular level during early development to improve the immediate and long-term health of offspring suffering from PAE.

Postantibiotic effects and postantibiotic sub-MIC effects of tilmicosin, erythromycin and tiamulin on erythromycin-resistant Streptococcus suis.

Science.gov (United States)

Wang, Liping; Zhang, Yuanshu

2009-10-01

The postantibiotic effects (PAEs) and postantibiotic sub-MIC effects (PA SMEs) of tilmicosin, erythromycin and tiamulin on erythromycin-susceptible and erythromycin-resistant strains of Streptococcus suis (M phenotype) were investigated in vitro. Tilmicosin and tiamulin induced significantly longer PAE and PA SME against both erythromycin-susceptible and erythromycin-resistant strains than did erythromycin. The durations of PAE and PA SMEs were proportional to the concentrations of drugs used for exposure. The PA SMEs were substantially longer than PAEs on S. suis (P<0.05) regardless of the antimicrobial used for exposure. The results indicated that the PAE and PA SME could help in the design of efficient control strategies for infection especially caused by erythromycin-resistant S. suis and that they may provide additional valuable information for the rational drug use in clinical practice.

Adsorption of Phthalates on Municipal Activated Sludge

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Hongbo Wang

2017-01-01

Full Text Available Phthalates (PAEs are commonly detected in discharge of municipal wastewater treatment plants. This study investigated the removal of six typical PAEs with activated sludge and the results revealed that concentrations of aqueous PAEs decreased rapidly during the beginning 15 min and reached equilibrium within 2 hours due to the adsorption of activated sludge. The process followed first-order kinetic equation, except for dioctyl phthalate (DOP. The factors influencing the adsorption were also evaluated and it was found that higher initial concentrations of PAEs enhanced the removal but affected little the adsorption equilibrium time. The adsorption of PAEs favored lower operating temperature (the optimum temperature was approximately 25°C in this research, which could be an exothermic process. Additionally, lower aqueous pH could also benefit the adsorption.

Simultaneous GC-MS determination of eight phthalates in total and migrated portions of plasticized polymeric toys and childcare articles.

Science.gov (United States)

Al-Natsheh, Mais; Alawi, Mahmoud; Fayyad, Manar; Tarawneh, Ibrahim

2015-03-15

A gas chromatography/mass spectrometric method was developed for the simultaneous determination of eight phthalic acid esters (PAEs) in toys and child care articles that are made of plasticized plastic. The novel method was used to determine the total concentration of the PAEs in addition to the migrated PAEs values into artificial saliva, under conditions that simulate real life situations. The extraction method, which was developed for the first time to determine the total concentration of PAEs, utilized a novel optimization of four parameters involving the solvent, time, temperature and weight of sample. The PAEs were extracted with tetrahydrofuran, as extraction the solvent, and using the ultrasonic water bath shaker for 30min, at room temperature. Another extraction method was developed to determine the migrated PAEs into artificial saliva at pH 6.2 and 37°C, implementing a liquid-liquid extraction with chloroform. Both methods were subjected to validation steps in terms of linearity, precision, accuracy and recovery, which ensured that all obtained results were well within the norms of acceptable limits and specifications. The analytes were separated at the following retention times: 4.99, 5.21, 5.31, 6.63, 7.41, 9.05min for di-"isobutyl" phthalate (DIBP), dibutyl phthalate (DBP), bis(2-methoxyethyl)phthalate (DMEP), benzyl butyl phthalate (BBP), dibutyl phthalate (DEHP) and di-n-octyl phthalate (DnOP), respectively. The chromatographic peaks corresponding to di-"isononyl" phthalate (DINP) and di-"isononyl" phthalate (DIDP), were separated, using the extracted ion chromatogram (EIC) mode within the time ranges of 8.05-12.10min for DINP and 8.50-14.50min for DIDP. The instrument detection limits for DIBP, DBP, DMEP, BBP, DEHP, DnOP, DINP and DIDP were determined at 0.100, 0.100, 0.045, 0.035, 0.015, 0.370, 0.320, 0.260μg/ml, respectively. The calibration curve working ranges were determined at 0.5-25μg/ml for DIBP, DBP, DMEP, BBP and DEHP, 2-100μg/ml for

Biosynthesis of amidated joining peptide from pro-adrenocorticotropin-endorphin

Energy Technology Data Exchange (ETDEWEB)

Cullen, E.I.; Mains, R.E. (Johns Hopkins Univ. School of Medicine, Baltimore, MD (USA))

1987-09-01

Joining peptide is the major alpha-amidated product of pro-ACTH/endorphin (PAE) in AtT-20 corticotropic tumor cells. To study intracellular joining peptide synthesis, affinity purified antibodies directed against gamma-MSH, joining peptide, and ACTH were used to immunoprecipitate extracts from biosynthetically labeled AtT-20 cells. Immunoprecipitates were analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and by tryptic peptide mapping on HPLC. In steady labeling experiments, radioactivity in amidated joining peptide (JP) increased roughly linearly with time, in the manner of a final product, whereas radioactivity associated with PAE (1-94)NH2 reached a constant value after 2-4 h, indicating that PAE(1-94)NH2 is an intermediate in the biosynthesis of JP. Radioactivity appeared in ACTH(1-39) well before JP, consistent with a cleavage order in which ACTH is cleaved from PAE(1-95) before JP sequences are cleaved from PAE(1-74). This conclusion was supported by tryptic peptide analyses of immunoprecipitates, which indicated that less than 5% of JP-related material is cleaved from PAE(1-74) before being cleaved from ACTH-related sequences. After a pulse label, radioactivity in PAE(1-94)NH2 reached a peak value after 1 h of chase and declined with a half-life of less than 1 h. Amidated JP increased to a constant level after 2 h of chase. Enough radiolabeled PAE(1-94)NH2 was detected to account for about half of the radioactivity found in amidated JP, indicating that about half of JP-related material is first cleaved from PAE(1-95) before being amidated. This result was corroborated using HPLC purification to determine both amidated and glycine-extended forms of JP.

Biosynthesis of amidated joining peptide from pro-adrenocorticotropin-endorphin

International Nuclear Information System (INIS)

Cullen, E.I.; Mains, R.E.

1987-01-01

Joining peptide is the major alpha-amidated product of pro-ACTH/endorphin (PAE) in AtT-20 corticotropic tumor cells. To study intracellular joining peptide synthesis, affinity purified antibodies directed against gamma-MSH, joining peptide, and ACTH were used to immunoprecipitate extracts from biosynthetically labeled AtT-20 cells. Immunoprecipitates were analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and by tryptic peptide mapping on HPLC. In steady labeling experiments, radioactivity in amidated joining peptide (JP) increased roughly linearly with time, in the manner of a final product, whereas radioactivity associated with PAE (1-94)NH2 reached a constant value after 2-4 h, indicating that PAE(1-94)NH2 is an intermediate in the biosynthesis of JP. Radioactivity appeared in ACTH(1-39) well before JP, consistent with a cleavage order in which ACTH is cleaved from PAE(1-95) before JP sequences are cleaved from PAE(1-74). This conclusion was supported by tryptic peptide analyses of immunoprecipitates, which indicated that less than 5% of JP-related material is cleaved from PAE(1-74) before being cleaved from ACTH-related sequences. After a pulse label, radioactivity in PAE(1-94)NH2 reached a peak value after 1 h of chase and declined with a half-life of less than 1 h. Amidated JP increased to a constant level after 2 h of chase. Enough radiolabeled PAE(1-94)NH2 was detected to account for about half of the radioactivity found in amidated JP, indicating that about half of JP-related material is first cleaved from PAE(1-95) before being amidated. This result was corroborated using HPLC purification to determine both amidated and glycine-extended forms of JP

Macht, machinaties en musea. Jan van der Hoeven, Hermann Schlegel en hun strijd om het Rijksmuseum van natuurlijke historie te Leiden

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H.L. de Jonge

2005-01-01

Full Text Available Might, machinations and museums. Jan van der Hoeven, Hermann Schlegel and their battle over the National Museum for Natural History in LeidenMuseums had a central place in nineteenth-century natural history. Aside from being important places for carrying out research into nature, they were also powerful vehicles for transmitting and communicating scientific knowledge. That is why, in the nineteenth century, natural history museums were frequently battlegrounds for rival scientists. Often, clashes over scientific matters were at the same time conflicts about power and space. After all, the naturalist who could get control over a museum’s collection and decide how the specimens should be classified and exhibited ultimately had the power to dictate which scientific knowledge was communicated; which story was told by a collection of specimens. This article is about the power struggle over the directorate of the National Museum of Natural History in Leiden that broke out between Jan van der Hoeven, Professor of Natural History and Comparative Anatomy at Leiden and Herman Schlegel, the museum’s chief curator. Both were rooted in very different natural historical traditions and had completely different views on the role of the museum and how the collection should be arranged and exhibited. In this article, we follow the two scientists in their attempts to gain support for their nominations. In this way, we also get a picture of nineteenth century Dutch political culture and the role scientists could play in it.

Postantibiotic effects and postantibiotic sub-MIC effects of tilmicosin, erythromycin and tiamulin on erythromycin-resistant Streptococcus suis

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Liping Wang

2009-12-01

Full Text Available The postantibiotic effects (PAEs and postantibiotic sub-MIC effects (PA SMEs of tilmicosin, erythromycin and tiamulin on erythromycin-susceptible and erythromycin-resistant strains of Streptococcus suis (M phenotype were investigated in vitro. Tilmicosin and tiamulin induced significantly longer PAE and PA SME against both erythromycin-susceptible and erythromycin-resistant strains than did erythromycin. The durations of PAE and PA SMEs were proportional to the concentrations of drugs used for exposure. The PA SMEs were substantially longer than PAEs on S. suis (P<0.05 regardless of the antimicrobial used for exposure. The results indicated that the PAE and PA SME could help in the design of efficient control strategies for infection especially caused by erythromycin-resistant S. suis and that they may provide additional valuable information for the rational drug use in clinical practice.

Devjatõi arhitekturnõi konkurs Europan vporu Tartu / Urmas Oja

Index Scriptorium Estoniae

Oja, Urmas, 1981-2012

2008-01-01

Üleeuroopalise arhitektuurikonkursi "Europan 9" tulemused Eesti võistlusaladel. Tallinna Paljassaare sadamaala: II koht - töö "Developing a Waterside City", Sayman Bostanci. Tartu Annelinna-äärne loodusväärtuslik krunt: I koht - "Urban Ecosystem Design", Pierre-Yves Rustant, II - "Pockets of Illusion", Yuri Gerrits, Martin Birgel. Toodud ka kaks äramärgitud tööd, Rootsi-Eesti ühisžürii liikmed (Eestist Andres Alver, Triin Ojari, varuliige Inga Raukas)

Tarbekunsti- ja Disainimuuseum taas avatud

Index Scriptorium Estoniae

2005-01-01

2. VI avati rekonstrueeritud muuseumihoone. Rekonstrueerimisprojekti autorid: Arhitektuuriagentuuri arhitekt Inga Raukas, sisearhitekt Monika Löve. Ehitustööd: Rihti Projekt. Avatud nahakunstinäitus "Järjehoidja" (kuraator Airi Ligi, kujundaja Siiri Nõva, näha saab ka nahakunsti üliõpilaste töid; filmiprogramm: Maya Yonesho "Üks uks", "Ecce libri" Pille Kivihallist, Tiina Piisangust ja Maarja Unduskist) ja rahvusvaheline köitekunstinäitus "Scripta manent III. Maailma parim asi", kujundaja Lennart Mänd

Marketing marketing : rede, op samenvattende wijze gepresenteerd 29 november 2013 door Dr. Karel Jan Alsem ter gelegenheid van zijn installatie als Lector Marketing/Marktgericht Ondernemen aan de Hanzehogeschool Groningen

NARCIS (Netherlands)

Alsem, Karel Jan

2013-01-01

Deze publicatie bevat de rede die Karel Jan Alsem gehouden heeft bij zijn installatie op 29 november 2013 als Lector Marketing/Marktgericht Ondernemen aan de Hanzehogeschool Groningen. Hij betoogt dat marketing een grotere strategische rol in organisaties zou moeten krijgen. Want marketing is bij

Crustal and mantle structure of the greater Jan Mayen-East Greenland region (NE Atlantic) from combined 3D structural, S-wave velocity, and gravity modeling

Science.gov (United States)

Tan, P.; Sippel, J.; Scheck-Wenderoth, M.; Meeßen, C.; Breivik, A. J.

2016-12-01

The study area is located between the Jan Mayen Ridge and the east coast of Greenland. It has a complex geological setting with the ultraslow Kolbeinsey and Mohn's spreading ridges, the anomalously shallow Eggvin Bank, the Jan Mayen Microcontinent (JMMC), and the tectonically active West Jan Mayen Fracture Zone (WJMFZ). In this study, we present the results of forward 3D structural, S-wave velocity, and gravity modeling which provide new insights into the deep crust and mantle structure and the wide-ranging influence of the Iceland Plume. The crustal parts of the presented 3D structural model are mainly constrained by local seismic refraction and reflection data. Accordingly, greatest crustal thicknesses (24 km) are observed on the northern boundary of the JMMC, while the average crustal thickness is 8.5 km and 4 km in the Kolbeinsey and Mohn's Ridge, respectively. The densities of the crustal parts are from previous studies. Additionally, the mantle density is derived from S-wave velocity data (between 50 and 250 km depth), while densities of the lithospheric mantle between the Moho and 50 km are calculated assuming isostatic equilibrium at 250 km depth. This is used as a starting density model which is further developed to obtain a reasonable fit between the calculated and measured (free-air) gravity fields. The observed S-wave tomographic data and the gravity modeling prove that the Iceland plume anomaly in the asthenosphere affects the lithospheric thickness and temperature, from the strongly influenced Middle Kolbeinsey Ridge, to the less affected North Kolbeinsey Ridge (Eggvin Bank), and to the little impacted Mohn's Ridge. Thus, the age-temperature relations of the different mid-ocean ridges of the study area are perturbed to different degrees controlled by the distance from the Iceland Plume. Furthermore, we find that the upper 50 km of lithospheric mantle are thermally affected by the plume only in the southwestern parts of the study area.

Sex differences in associations between white matter microstructure and gonadal hormones in children and adolescents with prenatal alcohol exposure.

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Uban, K A; Herting, M M; Wozniak, J R; Sowell, E R

2017-09-01

Despite accumulating evidence from animal models demonstrating that prenatal alcohol exposure (PAE) results in life-long neuroendocrine dysregulation, very little is known on this topic among humans with fetal alcohol spectrum disorders (FASD). We expected that alterations in gonadal hormones might interfere with the typical development of white matter (WM) myelination, and in a sex-dependent manner, in human adolescents with FASD. In order to investigate this hypothesis, we used diffusion tensor imaging (DTI) to assess: 1) whether or not sex moderates the impact of PAE on WM microstructure; and 2) how gonadal hormones relate to alterations in WM microstructure in children and adolescents affected by PAE. 61 youth (9 to 16 yrs.; 49% girls; 50% PAE) participated as part of the Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD). DTI scans and passive drool samples were obtained to examine neurodevelopmental associations with testosterone (T) and dehydroepiandrosterone (DHEA) levels in boys and girls, and estradiol (E2) and progesterone (P) levels in girls. Tract-based spatial statistics were utilized to generate fractional anisotropy (FA) and mean diffusivity (MD) for 9 a priori WM regions of interest (ROIs). As predicted, alterations in FA were observed in adolescents with PAE relative to controls, and these differences varied by sex. Girls with PAE exhibited lower FA (Inferior fronto-occipital and Uncinate fasciculi) while boys with PAE exhibited higher FA (Callosal body, Cingulum, Corticospinal tract, Optic radiation, Superior longitudinal fasciculus) relative to age-matched controls. When gonadal hormone levels were examined in relation to DTI measures, additional group differences in FA were revealed, demonstrating that neuroendocrine factors are associated with PAE-related brain alterations. These findings provide human evidence that PAE relates to sex-specific differences in WM microstructure, and underlying alterations in gonadal hormone

Comparing diagnostic classification of neurobehavioral disorder associated with prenatal alcohol exposure with the Canadian fetal alcohol spectrum disorder guidelines: a cohort study.

Science.gov (United States)

Sanders, James L; Breen, Rebecca E Hudson; Netelenbos, Nicole

2017-01-01

Diagnostic criteria have recently been introduced in the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5), for neurobehavioral disorder associated with prenatal alcohol exposure (ND-PAE). The purpose of this study is to assess the classification of this condition using the Canadian fetal alcohol spectrum disorder (FASD) multidisciplinary diagnostic guidelines as the standard of comparison. First, classification of ND-PAE was compared with Canadian FASD diagnoses of fetal alcohol syndrome (FAS), partial FAS and alcohol-related neurodevelopmental disorder. Second, classification of ND-PAE was compared with FAS and pFAS only, a criterion for which includes facial features highly predictive of prenatal alcohol exposure and effects. Eighty-two patients underwent multidisciplinary clinical evaluations using the Canadian FASD diagnostic guidelines between 2011 and 2015. Two clinicians independently reviewed patient files for evidence of diagnostic criteria for ND-PAE when applying an impairment cut-off level of 2 or more standard deviations below the mean, or clinically significant impairment in the absence of standardized norm-referenced measures. Good interrater reliability was established between clinicians (κ = 0.79). Classifications of ND-PAE and Canadian FASD diagnoses, including alcohol-related neurodevelopmental disorder, were moderately correlated (Cramer V [82] = 0.44, p 0.05). Although there is considerable overlap between both sets of criteria, ND-PAE was less likely to identify patients with FASD. Although the neurobehavioral domains assessed by ND-PAE are supported in research, its diagnostic structure restricts the identification of FASD at the impairment threshold of 2 or more standard deviations. A disconnect remains with regard to impairment thresholds between FASD, which relies on neurodevelopmental data, and ND-PAE, which relies on clinical judgment.

Effects of sex and housing on social, spatial, and motor behavior in adult rats exposed to moderate levels of alcohol during prenatal development.

Science.gov (United States)

Rodriguez, Carlos I; Magcalas, Christy M; Barto, Daniel; Fink, Brandi C; Rice, James P; Bird, Clark W; Davies, Suzy; Pentkowski, Nathan S; Savage, Daniel D; Hamilton, Derek A

2016-10-15

Persistent deficits in social behavior, motor behavior, and behavioral flexibility are among the major negative consequences associated with exposure to ethanol during prenatal development. Prior work from our laboratory has linked moderate prenatal alcohol exposure (PAE) in the rat to deficits in these behavioral domains, which depend upon the ventrolateral frontal cortex (Hamilton et al., 2014) [20]. Manipulations of the social environment cause modifications of dendritic morphology and experience-dependent immediate early gene expression in ventrolateral frontal cortex (Hamilton et al., 2010) [19], and may yield positive behavioral outcomes following PAE. In the present study we evaluated the effects of housing PAE rats with non-exposed control rats on adult behavior. Rats of both sexes were either paired with a partner from the same prenatal treatment condition (ethanol or saccharin) or from the opposite condition (mixed housing condition). At four months of age (∼3 months after the housing manipulation commenced), social behavior, tongue protrusion, and behavioral flexibility in the Morris water task were measured as in (Hamilton et al., 2014) [20]. The behavioral effects of moderate PAE were primarily limited to males and were not ameliorated by housing with a non-ethanol exposed partner. Unexpectedly, social behavior, motor behavior, and spatial flexibility were adversely affected in control rats housed with a PAE rat (i.e., in mixed housing), indicating that housing with a PAE rat has broad behavioral consequences beyond the social domain. These observations provide further evidence that moderate PAE negatively affects social behavior, and underscore the importance of considering potential negative effects of housing with PAE animals on the behavior of critical comparison groups. Copyright © 2016 Elsevier B.V. All rights reserved.

Fate and impact of phthalates in activated sludge treated municipal wastewater on the water bodies in the Eastern Cape, South Africa.

Science.gov (United States)

Salaudeen, Taofeek; Okoh, Omobola; Agunbiade, Foluso; Okoh, Anthony

2018-07-01

The concentration and fates of six priority phthalate esters (PAEs); dimethyl phthalate (DMP), diethyl phthalate (DEP), di-n-butyl phthalate (DBP), benzyl butyl phthalate (BBP), di (2-ethyl hexyl) phthalate (DEHP), and di-n-octyl phthalate (DOP) in wastewaters from the wastewater treatment plants (WWTPs) which adopted the activated sludge technology in the Amathole Municipality, Eastern Cape, South Africa were investigated. The six PAEs were detected in all the influents and in almost all the WWTP effluent of which DBP was the most abundant in the influent followed by DEHP. Influent concentration of DBP in the three WWTPs ranged between 2.7 and 2488 μgL -1 and the average effluent concentration was 4.90-8.88 μgL -1 . On average, the concentration of PAEs in WWTP effluents were higher than PAEs in the upstream and downstream of the discharging point suggesting PAE impact on the receiving water. The concentrations detected in the sludge of which DEHP and DBP were more pervasive ranged between 130 and 1094 μg/g dry weight. The average removal capacity; 27.3-99.5% suggested more adsorption on settling particles and sludge than biodegradation as high significant correlation was found between PAEs removal, total suspended solid and turbidity. Removal of high molecular weight and high octanol-water partition coefficient (logK ow ) PAEs through adsorption was found to be significantly high. It could be concluded that the release of PAEs into the sludge, and the amount in the final effluent which were found to exceed the acceptable levels allowed internationally, raises safety concern for both aquatic and human's health. Copyright © 2018 Elsevier Ltd. All rights reserved.

Phthalate release in leachate from municipal landfills of central Poland.

Science.gov (United States)

Wowkonowicz, Paweł; Kijeńska, Marta

2017-01-01

Phthalate diesters (PAEs) are used as plasticizer additives to polymer chains to make the material more flexible and malleable. PAEs are bonded physically, not chemically, to the polymeric matrix and can migrate to and leach from the product surface, posing a serious danger to the environment and human health. There have been a number of studies on PAE concentrations in landfill leachate conducted in the EU and around the world, though few in Poland. In the present study, the leachate of five municipal landfills was analyzed for the presence of PAEs. Raw leachate was sampled four times over the period of one year in 2015/16. It was the first large study on this subject in Poland. PAEs were detected in the leachate samples on all of the landfills, thereby indicating that PAEs are ubiquitous environmental contaminants. The following PAEs were detected in at least one sample: Di(2-ethylhexyl) phthalate (DEHP), Diethyl phthalate (DEP), Dimethyl phthalate (DMP), Di-n-butyl phthalate (DBP), Di-isobutylphthalate (DIBP). Out of all ten PAEs, DEHP was the most predominant, with concentrations up to 73.9 μg/L. DEHP was present in 65% of analyzed samples (in 100% of samples in spring, 80% in winter, and 40% in summer and autumn). In only 25% of all samples DEHP was below the acceptable UE limit for surface water (1.3 μg/L), while 75% was from 1.7 to 56 times higher than that value. On the two largest landfills DEHP concentrations were observed during samples from all four seasons, including on a landfill which has been remediated and closed for the last 5 years.

Organophosphate esters and phthalate esters in human hair from rural and urban areas, Chongqing, China: Concentrations, composition profiles and sources in comparison to street dust.

Science.gov (United States)

He, Ming-Jing; Lu, Jun-Feng; Ma, Jing-Ye; Wang, Huan; Du, Xiao-Fan

2018-06-01

Human hair and street dust from rural and urban areas in Chongqing were collected to analyze Organophosphate esters (OPEs) and phthalate esters (PAEs). Concentrations of OPEs in urban hair were significantly higher than those in rural hair, whereas PAEs concentrations in rural hair were significantly higher than those in urban hair. Different composition patterns of OPEs were observed in rural and urban hair, where tris (2-chloroisopropyl) phosphate (TCIPP), tris (butyl) phosphate (TNBP) and triphenyl phosphate (TPHP) were the dominating analogues in rural hair, accounting for 62.1% of the OPEs burden, and tris (methylphenyl) phosphate (TMPP) exhibited a high contribution in urban hair, responsible for 51.3% of total OPEs, which differed from the composition profiles in corresponding street dust. Analogous composition patterns of PAEs were found in hair of both areas. Di-(2-ethylhexyl) phthalate (DEHP), dibutyl phthalate (DNBP), diisobutyl phthalate (DIBP) and diethyl phthalate (DEP) were the most abundant analogues in hair samples, while DEHP was the predominant analogue in dust samples. No clear tendency was obtained between the increasing ages and the concentrations of both compounds. Most OPEs and PAEs congeners showed significantly positive correlation with one another in rural hair. On the contrary, different correlation patterns were observed in urban hair for OPEs and PAEs, indicating multiple or additional sources existed in urban areas. Significant correlations of OPEs and PAEs were found between hair and corresponding street dust samples, but poor correlations of OPEs and PAEs were observed between rural hair and rural indoor dust, suggesting that street dust may be a predominant exogenous source for human exposure to OPEs and PAEs in this area. Copyright © 2018 Elsevier Ltd. All rights reserved.

Death on demand? An analysis of physician-administered euthanasia in The Netherlands.

Science.gov (United States)

Preston, Robert

2018-03-01

Physician-administered euthanasia (PAE) was legalized, along with physician-assisted suicide (PAS), in The Netherlands in 2001. Annual reports of the Dutch Regional Euthanasia Review Committees, the committees' 2015 published Code of Practice and research studies. There is a general openness about the practice of PAE/PAS in The Netherlands and an avoidance of misleading euphemisms. The 2001 law also includes arrangements for post-event review of PAE/PAS decisions. Rising numbers of annually reported deaths from PAE and uncertainty over actual numbers. Movement away from the principle that euthanasia must take place within an established doctor-patient relationship. Increasing extension of the 2001 law to people with mental health conditions, dementia and multiple co-morbidities. Nature of the post-event scrutiny applied to reported cases. The predominance of PAE over PAS where both are legalized raises questions over how these two acts are perceived and whether there are implications for such laws. Are the criteria for PAE/PAS in the 2001 law appropriate for a law of this nature? What should be the respective roles of the second-opinion doctors and the review committees?

Effect of propolis alcoholic extract on the weight gain, carcass traits and cecal pH of growing rabbits

Directory of Open Access Journals (Sweden)

Joseli Alves Ferreira Zanato

2007-06-01

Full Text Available The objective of this experiment was to evaluate the effect of different rates of propolis alcoholic extract (PAE on the weight gain, carcass traits and cecal pH of growing rabbits. Forty White New Zealand rabbits were distributed in a completely randomized experimental design consisting of four treatments and ten replicates per treatment. The rabbits were allocated individually in wire cages containing a nipple drinker and a semi-automatic feeder. The treatments were: T1 = control, T2 = 1ml of ethanol, T3 = 0.8ml of PAE, and T4 = 1.5ml of PAE. Commercial feed and water were provided ad libitum to the animals, and the treatment with cereal alcohol and PAE was administered orally using a 2ml syringe. It was concluded that the addition of PAE to the rabbits’ feeding resulted in weight gain, carcass traits and cecal pH similar to those of animals which received the diets with ethanol without any addition, except for the paw weight, that was higher in the rabbits which were given PAE, and for the gastric system, that had a higher weight in the rabbits which received no addition to their diet.

Popliteal artery entrapment syndrome

International Nuclear Information System (INIS)

Klooster, N.J.J.; Janevski, B.K.; Kitslaar, P.

1988-01-01

Two patients with unilateral popliteal artery entrapment syndrome (PAES) are reported. The importance of diligence in angiographic diagnosis and recognition of the so-called 'functional' PAES group as a separate entity are stressed. It is inferred from our material that a surgical approach for PAES is to be advocated since surgical release of the entrapment can lead to complete resolution of symptoms regardless of aetiology. (orig.) [de

Prenatal alcohol exposure results in long-term serotonin neuron deficits in female rats: modulatory role of ovarian steroids.

Science.gov (United States)

Sliwowska, Joanna H; Song, Hyun Jung; Bodnar, Tamara; Weinberg, Joanne

2014-01-01

Previous studies on male rodents found that prenatal alcohol exposure (PAE) decreases the number of serotonin immunoreactive (5-HT-ir) neurons in the brainstem. However, data on the effects of PAE in females are lacking. In light of known sex differences in responsiveness of the 5-HT system and known effects of estrogen (E2 ) and progesterone (P4 ) in the brain, we hypothesized that sex steroids will modulate the adverse effects of PAE on 5-HT neurons in adult females. Adult females from 3 prenatal groups (Prenatal alcohol-exposed [PAE], Pair-fed [PF], and ad libitum-fed Controls [C]) were ovariectomized (OVX), with or without hormone replacement, or underwent Sham OVX. 5-HT-ir cells were examined in key brainstem areas. Our data support the hypothesis that PAE has long-term effects on the 5-HT system of females and that ovarian steroids have a modulatory role in these effects. Intact (Sham OVX) PAE females had marginally lower numbers of 5-HT-ir neurons in the dorsal raphe nucleus of the brainstem compared with PF and C females. This marginal difference became significant following removal of hormones by OVX. Replacement with E2 restored the number of 5-HT-ir neurons in PAE females to control levels, while P4 reversed the effects of E2 . Importantly, despite these differential responses of the 5-HT system to ovarian steroids, there were no differences in E2 and P4 levels among prenatal treatment groups. These data demonstrate long-term, adverse effects of PAE on the 5-HT system of females, as well as differential sensitivity of PAE compared with control females to the modulatory effects of ovarian steroids on 5-HT neurons. Our findings have important implications for understanding sex differences in 5-HT dysfunction in depression/anxiety disorders and the higher rates of these mental health problems in individuals with fetal alcohol spectrum disorder. Copyright © 2013 by the Research Society on Alcoholism.

Globes and Teaching Aids Manufactured by Jan Felkl Company for the Polish Market

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Malgorzata Taborska

2016-05-01

Full Text Available Jan Felkl company from Roztoky (Roztok near Prague manufactured globes in seventeen language versions, since 1861 also in Polish language. The company was active until 1952, but it ceased to manufacture Polish-language globes as early as in 1914. In the aftermath of the First World War, and with the development of printing business, the demand for Czech globes shrank. It is difficult to estimate the overall output of Polish- language globes manufactured by Felkl’s company throughout the 53 years it operated. From catalogues and the surviving globes we know that terrestrial globes in six sizes, folding globes in two sizes, celestial globes (probably in four sizes, as well as telluria, lunaria and planetaria were manufactured for the Polish market. It is difficult to decide how many editions of individual types of globes were issued. Polish names were compiled by Franciszek Waligórski (one globe and Mirosław Suchecki. Only 28 globes have survived to this day, including one celestial globe. Most of them are globes of an 8-inch diameter, approved by the Austrian ministries as teaching aids for schools. Nearly half of the surviving globes date from the years 1894–1914. Only ten items are in museums.

Prenatal alcohol exposure modifies glucocorticoid receptor subcellular distribution in the medial prefrontal cortex and impairs frontal cortex-dependent learning.

Directory of Open Access Journals (Sweden)

Andrea M Allan

Full Text Available Prenatal alcohol exposure (PAE has been shown to impair learning, memory and executive functioning in children. Perseveration, or the failure to respond adaptively to changing contingencies, is a hallmark on neurobehavioral assessment tasks for human fetal alcohol spectrum disorder (FASD. Adaptive responding is predominantly a product of the medial prefrontal cortex (mPFC and is regulated by corticosteroids. In our mouse model of PAE we recently reported deficits in hippocampal formation-dependent learning and memory and a dysregulation of hippocampal formation glucocorticoid receptor (GR subcellular distribution. Here, we examined the effect of PAE on frontal cortical-dependent behavior, as well as mPFC GR subcellular distribution and the levels of regulators of intracellular GR transport. PAE mice displayed significantly reduced response flexibility in a Y-maze reversal learning task. While the levels of total nuclear GR were reduced in PAE mPFC, levels of GR phosphorylated at serines 203, 211 and 226 were not significantly changed. Cytosolic, but not nuclear, MR levels were elevated in the PAE mPFC. The levels of critical GR trafficking proteins, FKBP51, Hsp90, cyclophilin 40, dynamitin and dynein intermediate chain, were altered in PAE mice, in favor of the exclusion of GR from the nucleus, indicating dysregulation of GR trafficking. Our findings suggest that there may be a link between a deficit in GR nuclear localization and frontal cortical learning deficits in prenatal alcohol-exposed mice.

Bell's palsy before Bell: Evert Jan Thomassen à Thuessink and idiopathic peripheral facial paralysis.

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van de Graaf, R C; IJpma, F F A; Nicolai, J-P A; Werker, P M N

2009-11-01

Bell's palsy is the eponym for idiopathic peripheral facial paralysis. It is named after Sir Charles Bell (1774-1842), who, in the first half of the nineteenth century, discovered the function of the facial nerve and attracted the attention of the medical world to facial paralysis. Our knowledge of this condition before Bell's landmark publications is very limited and is based on just a few documents. In 1804 and 1805, Evert Jan Thomassen à Thuessink (1762-1832) published what appears to be the first known extensive study on idiopathic peripheral facial paralysis. His description of this condition was quite accurate. He located several other early descriptions and concluded from this literature that, previously, the condition had usually been confused with other afflictions (such as 'spasmus cynicus', central facial paralysis and trigeminal neuralgia). According to Thomassen à Thuessink, idiopathic peripheral facial paralysis and trigeminal neuralgia were related, being different expressions of the same condition. Thomassen à Thuessink believed that idiopathic peripheral facial paralysis was caused by 'rheumatism' or exposure to cold. Many aetiological theories have since been proposed. Despite this, the cold hypothesis persists even today.

Unilateral Versus Bilateral Prostatic Arterial Embolization for Lower Urinary Tract Symptoms in Patients with Prostate Enlargement

Energy Technology Data Exchange (ETDEWEB)

Bilhim, Tiago, E-mail: tiagobilhim@hotmail.com [Universidade Nova de Lisboa (UNL), Departamento Universitario de Anatomia, Faculdade de Ciencias Medicas (FCM) (Portugal); Pisco, Joao; Rio Tinto, Hugo; Fernandes, Lucia [Interventional Radiology, Saint Louis Hospital (Portugal); Campos Pinheiro, Luis [Universidade Nova de Lisboa (UNL), Departamento Universitario de Urologia, Faculdade de Ciencias Medicas (FCM) (Portugal); Duarte, Marisa; Pereira, Jose A. [Interventional Radiology, Saint Louis Hospital (Portugal); Oliveira, Antonio G. [Universidade Nova de Lisboa (UNL), Biostatistics Department, Faculdade de Ciencias Medicas (FCM) (Portugal); O' Neill, Joao [Universidade Nova de Lisboa (UNL), Departamento Universitario de Anatomia, Faculdade de Ciencias Medicas (FCM) (Portugal)

2013-04-15

This study was designed to compare baseline data and clinical outcome between patients with prostate enlargement/benign prostatic hyperplasia (PE/BPH) who underwent unilateral and bilateral prostatic arterial embolization (PAE) for the relief of lower urinary tract symptoms (LUTS). This single-center, ambispective cohort study compared 122 consecutive patients (mean age 66.7 years) with unilateral versus bilateral PAE from March 2009 to December 2011. Selective PAE was performed with 100- and 200-{mu}m nonspherical polyvinyl alcohol (PVA) particles by a unilateral femoral approach. Bilateral PAE was performed in 103 (84.4 %) patients (group A). The remaining 19 (15.6 %) patients underwent unilateral PAE (group B). Mean follow-up time was 6.7 months in group A and 7.3 months in group B. Mean prostate volume, PSA, International prostate symptom score/quality of life (IPSS/QoL) and post-void residual volume (PVR) reduction, and peak flow rate (Qmax) improvement were 19.4 mL, 1.68 ng/mL, 11.8/2.0 points, 32.9 mL, and 3.9 mL/s in group A and 11.5 mL, 1.98 ng/mL, 8.9/1.4 points, 53.8 mL, and 4.58 mL/s in group B. Poor clinical outcome was observed in 24.3 % of patients from group A and 47.4 % from group B (p = 0.04). PAE is a safe and effective technique that can induce 48 % improvement in the IPSS score and a prostate volume reduction of 19 %, with good clinical outcome in up to 75 % of treated patients. Bilateral PAE seems to lead to better clinical results; however, up to 50 % of patients after unilateral PAE may have a good clinical outcome.

[Magnetic resonance imaging of the prostate: usefulness of diffusion sequences in detecting postembolization ischemia in patients with benign prostatic hyperplasia].

Science.gov (United States)

Serrano, E; Ocantos, J; Kohan, A; Kisilevsky, N; Napoli, N; García-Mónaco, R

2016-01-01

To analyze the usefulness of diffusion magnetic resonance (MR) sequences before and after prostatic artery embolization (PAE) in patients with benign prostatic hyperplasia (BPH). We analyzed MR studies done before (7-10 days) and after (30 days) PAE in 19 patients with BPH treated with PAE between June 2012 and December 2013. We used 1.5 Tesla scanners with body surface coils. In pre-PAE MR studies, we recorded mean b40 values and minimum (min) and maximum (max) apparent diffusion coefficient (ADC) values. In post-PAE MR studies, we recorded b40, b400, and b1000 values and min, mean, and max ADC values. We compared diffusion behavior/ADC before and after PAE and areas without ischemia. We correlated these with decreased prostatic volume (PV). We identified ischemia with contrast in 8 (42.1%) patients. No significant difference was found in mean b40 (p= 0.1650) or in the b40 ratio (p= 0.8868) between patients with ischemia and those without before PAE. Min b40, b40 ratio, and min ADC values differed significantly between ischemic areas and nonischemic areas within patients [p= 0.048 (b40min and ratio) and p= 0.002 (min ADC)]. No significant correlation was found between the percentage decrease in PV and mean b40 (p= 0.8490) or b40 ratio (p=0.8573). Post-PAE ischemia generates objective changes in diffusion and ADC values that enable ischemic sectors to be differentiated from nonischemic sectors. Future studies should analyze whether it is possible to subjectively differentiate between these areas through the visualization of nonischemic sectors and the feasibility of replacing them with contrast to detect ischemia. Copyright © 2015 SERAM. Published by Elsevier España, S.L.U. All rights reserved.

Robotic-Assisted Versus Manual Prostatic Arterial Embolization for Benign Prostatic Hyperplasia: A Comparative Analysis

Energy Technology Data Exchange (ETDEWEB)

Bagla, Sandeep, E-mail: sandeep.bagla@gmail.com [Vascular Institute of Virginia, LLC (United States); Smirniotopoulos, John [New York Presbyterian Hospital/Weill Cornell Medical Center (United States); Orlando, Julie C.; Piechowiak, Rachel [Vascular Institute of Virginia, LLC (United States)

2017-03-15

PurposeProstatic artery embolization (PAE) is a safe and efficacious procedure for benign prostatic hyperplasia (BPH), though is technically challenging. We present our experience of technical and clinical outcomes of robotic and manual PAE in patients with BPH.Materials and MethodsIRB-approved retrospective study of 40 consecutive patients 49–81 years old with moderate or severe grade BPH from May 2014 to July 2015: 20 robotic-assisted PAE (group 1), 20 manual PAE (group 2). Robotic-assisted PAE was performed using the Magellan Robotic System. American Urological Association (AUA-SI) score, cost, technical and clinical success, radiation dose, fluoroscopy, and procedure time were reviewed. Statistical analysis was performed within and between each group using paired t test and one-way analysis of variance respectively, at 1 and 3 months.ResultsNo significant baseline differences in age and AUA-SI between groups. Technical success was 100% (group 1) and 95% (group 2). One unsuccessful subject from group 2 returned for a successful embolization using robotic assistance. Fluoroscopy and procedural times were similar between groups, with a non-significant lower patient radiation dose in group 1 (30,632.8 mGy/cm{sup 2} vs 35,890.9, p = 0.269). Disposable cost was significantly different between groups with the robotic-assisted PAE incurring a higher cost (group 1 $4530.2; group 2 $1588.5, p < 0.0001). Clinical improvement was significant in both arms at 3 months: group 1 mean change in AUA-SI of 8.3 (p = 0.006), group 2: 9.6 (p < 0.0001). No minor or major complications occurred.ConclusionsRobotic-assisted PAE offers technical success comparable to manual PAE, with similar clinical improvement with an increased cost.

Robotic-Assisted Versus Manual Prostatic Arterial Embolization for Benign Prostatic Hyperplasia: A Comparative Analysis

International Nuclear Information System (INIS)

Bagla, Sandeep; Smirniotopoulos, John; Orlando, Julie C.; Piechowiak, Rachel

2017-01-01

PurposeProstatic artery embolization (PAE) is a safe and efficacious procedure for benign prostatic hyperplasia (BPH), though is technically challenging. We present our experience of technical and clinical outcomes of robotic and manual PAE in patients with BPH.Materials and MethodsIRB-approved retrospective study of 40 consecutive patients 49–81 years old with moderate or severe grade BPH from May 2014 to July 2015: 20 robotic-assisted PAE (group 1), 20 manual PAE (group 2). Robotic-assisted PAE was performed using the Magellan Robotic System. American Urological Association (AUA-SI) score, cost, technical and clinical success, radiation dose, fluoroscopy, and procedure time were reviewed. Statistical analysis was performed within and between each group using paired t test and one-way analysis of variance respectively, at 1 and 3 months.ResultsNo significant baseline differences in age and AUA-SI between groups. Technical success was 100% (group 1) and 95% (group 2). One unsuccessful subject from group 2 returned for a successful embolization using robotic assistance. Fluoroscopy and procedural times were similar between groups, with a non-significant lower patient radiation dose in group 1 (30,632.8 mGy/cm"2 vs 35,890.9, p = 0.269). Disposable cost was significantly different between groups with the robotic-assisted PAE incurring a higher cost (group 1 $4530.2; group 2 $1588.5, p < 0.0001). Clinical improvement was significant in both arms at 3 months: group 1 mean change in AUA-SI of 8.3 (p = 0.006), group 2: 9.6 (p < 0.0001). No minor or major complications occurred.ConclusionsRobotic-assisted PAE offers technical success comparable to manual PAE, with similar clinical improvement with an increased cost.

Unilateral Versus Bilateral Prostatic Arterial Embolization for Lower Urinary Tract Symptoms in Patients with Prostate Enlargement

International Nuclear Information System (INIS)

Bilhim, Tiago; Pisco, João; Rio Tinto, Hugo; Fernandes, Lúcia; Campos Pinheiro, Luís; Duarte, Marisa; Pereira, José A.; Oliveira, António G.; O’Neill, João

2013-01-01

This study was designed to compare baseline data and clinical outcome between patients with prostate enlargement/benign prostatic hyperplasia (PE/BPH) who underwent unilateral and bilateral prostatic arterial embolization (PAE) for the relief of lower urinary tract symptoms (LUTS). This single-center, ambispective cohort study compared 122 consecutive patients (mean age 66.7 years) with unilateral versus bilateral PAE from March 2009 to December 2011. Selective PAE was performed with 100- and 200-μm nonspherical polyvinyl alcohol (PVA) particles by a unilateral femoral approach. Bilateral PAE was performed in 103 (84.4 %) patients (group A). The remaining 19 (15.6 %) patients underwent unilateral PAE (group B). Mean follow-up time was 6.7 months in group A and 7.3 months in group B. Mean prostate volume, PSA, International prostate symptom score/quality of life (IPSS/QoL) and post-void residual volume (PVR) reduction, and peak flow rate (Qmax) improvement were 19.4 mL, 1.68 ng/mL, 11.8/2.0 points, 32.9 mL, and 3.9 mL/s in group A and 11.5 mL, 1.98 ng/mL, 8.9/1.4 points, 53.8 mL, and 4.58 mL/s in group B. Poor clinical outcome was observed in 24.3 % of patients from group A and 47.4 % from group B (p = 0.04). PAE is a safe and effective technique that can induce 48 % improvement in the IPSS score and a prostate volume reduction of 19 %, with good clinical outcome in up to 75 % of treated patients. Bilateral PAE seems to lead to better clinical results; however, up to 50 % of patients after unilateral PAE may have a good clinical outcome.

A comprehensive assessment of human exposure to phthalates from environmental media and food in Tianjin, China.

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Ji, Yaqin; Wang, Fumei; Zhang, Leibo; Shan, Chunyan; Bai, Zhipeng; Sun, Zengrong; Liu, Lingling; Shen, Boxiong

2014-08-30

A total of 448 samples including foodstuffs (rice, steamed bun, vegetables, meat, poultry, fish, milk and fruits), ambient PM10, drinking water, soil, indoor PM10 and indoor dust samples from Tianjin were obtained to determine the distribution of six priority phthalates (PAEs) and assess the human exposure to them. The results indicated that DBP and DEHP were the most frequently detected PAEs in these samples. The concentrations of PAEs in environmental media were higher than those in food. We estimated the daily intake (DI) of PAEs via ingestion, inhalation and dermal absorption from five sources (food, water, air, dust and soil). Dietary intake was the main exposure source to DEP, BBP, DEHP and DOP, whereas water ingestion/absorption was the major source of exposure to DBP, DEHP and DOP. Although food and water were the overwhelmingly predominant sources of PAEs intake by Tianjin population, contaminated air was another important source of DMP, DEP and DBP contributing to up to 45% of the exposure. The results of this study will help in understanding the major pathways of human exposure to PAEs. These findings also suggest that human exposure to phthalate esters via the environment should not be overlooked. Copyright © 2014 Elsevier B.V. All rights reserved.

Production of a biodegradable plastic-degrading enzyme from cheese whey by the phyllosphere yeast Pseudozyma antarctica GB-4(1)W.

Science.gov (United States)

Watanabe, Takashi; Shinozaki, Yukiko; Suzuki, Ken; Koitabashi, Motoo; Yoshida, Shigenobu; Sameshima-Yamashita, Yuka; Kuze Kitamoto, Hiroko

2014-08-01

Cheese whey is a by-product of cheese production and has high concentrations of lactose (about 5%) and other nutrients. Pseudozyma antarctica produces a unique cutinase-like enzyme, named PaE, that efficiently degrades biodegradable plastics. A previous study showed that a combination of 1% oil and 0.5% lactose increased cutinase-like enzyme production by another species of yeast. In this study, to produce PaE from cheese whey, we investigated the effects of soybean oil on PaE production (expressed as biodegradable plastic-degrading activity) by P. antarctica growing on lactose or cheese whey. In flask cultures, the final PaE activity was only 0.03 U/ml when soybean oil was used as the sole carbon source, but increased to 1.79 U/ml when a limited amount of soybean oil (under 0.5%) was combined with a relatively high concentration of lactose (6%). Using a 5-L jar fermentor with lactose fed-batch cultivation and periodic soybean oil addition, about 14.6 U/ml of PaE was obtained after 5 days of cultivation. When the lactose was replaced with cheese whey, PaE production was 10.8 U/ml after 3 days of cultivation. Copyright © 2014 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

Pathological bolus exposure may define gastro-esophageal reflux better than pathological acid exposure in patients with globus.

Science.gov (United States)

Sinn, Dong Hyun; Kim, Beom Jin; Son, Hee Jung; Kim, Jae J; Rhee, Jong Chul; Rhee, Poong-Lyul

2012-01-01

Conventionally, pathological acid exposure (PAE), defined by acid reflux only, is used to identify gastro-esophageal reflux disease (GERD). However, weak acid reflux or non-acid reflux also induces reflux symptoms. Defining abnormal reflux based on all reflux episodes may better identify GERD and would be more useful among patients with atypical GERD symptoms, such as globus. Impedance-pHmetry results of 31 globus patients, off acid suppressants, were analysed. A median of 24 episodes of reflux were observed. Of the reflux episodes, 54% were non-acid reflux and 50% reached the proximal extent. PAE was observed in 6 patients (19%). For 5 patients (16%) without PAE, there was evidence of increased bolus exposure compared to normal controls (an intraesophageal bolus exposure for more than 1.4% of the recording time, defined as pathological bolus exposure, PBE). When GERD was defined by PAE or esophagitis, the prevalence of GERD was 29%. When GERD was defined by PBE, PAE or esophagitis, the prevalence was 42%. PBE identified 13% of the patients who otherwise would have been missed. A significant proportion of patients without PAE had evidence of PBE. PBE may be a more useful definition for identifying patients with abnormal increase in reflux in patients with globus. Further studies are warranted.

Responsiveness of the Oswestry Disability Index and the Roland Morris Disability Questionnaire in Italian subjects with sub-acute and chronic low back pain.

Science.gov (United States)

Monticone, Marco; Baiardi, Paola; Vanti, Carla; Ferrari, Silvano; Pillastrini, Paolo; Mugnai, Raffaele; Foti, Calogero

2012-01-01

An ability to assess longitudinal changes in health status is crucial for the outcome measures used in treatment efficacy trials. The aim of this study was to verify the responsiveness of the Italian versions of the Oswestry Disability Index (ODI) and the Roland Morris Disability Questionnaire (RMDQ) in subjects with subacute or chronic low back pain (LBP). At the beginning and end of an 8 week rehabilitation programme, 179 patients completed a booklet containing the ODI, the RMDQ, a 0-10 numerical rating scale (NRS), and the 36-item Short-Form Health Survey (SF-36). A global perception of change scale was also completed at the end of the programme, and collapsed to produce a dichotomous outcome (i.e. improved vs. not improved). Responsiveness was assessed by means of distribution methods [minimum detectable change (MDC); effect size (ES); standardised response mean (SRM)] and anchor-based methods (ROC curves). The MDC for the ODI and RMDQ was, respectively, 13.67 and 4.87; the ES was 0.53 and 0.68; and the SRM was 0.80 and 0.81. ROC analysis revealed an area under the curve of 0.71 for the ODI and 0.64 for the RMDQ, thus indicating discriminating capacity; the best cut-off point for the dichotomous outcome was 9.5 for the ODI (sensitivity 76% and specificity 63%) and 2.5 for the RMDQ (sensitivity 62% and specificity 55%). These estimates were comparable between the subacute and chronic subjects. Both the ODI and the RMDQ moderately correlated with the SF-36 and NRS (Spearman's and Pearson's correlation coefficients of >0.30). The Italian ODI and RMDQ proved to be sensitive in detecting clinical changes after conservative treatment for subacute and chronic LBP. Our findings are consistent with those published in the literature, thus allowing cross-cultural comparisons and stimulating cross-national studies.

Study on the interaction of phthalate esters to human serum albumin by steady-state and time-resolved fluorescence and circular dichroism spectroscopy

Energy Technology Data Exchange (ETDEWEB)

Xie, Xiaoyun [National Key Laboratory of Organic Chemistry, Lanzhou University, Lanzhou 730000 (China); College of Earth and Environmental Sciences, Lanzhou University, Lanzhou 730000 (China); Wang, Zhaowei [College of Earth and Environmental Sciences, Lanzhou University, Lanzhou 730000 (China); Zhou, Ximin; Wang, Xiaoru [National Key Laboratory of Organic Chemistry, Lanzhou University, Lanzhou 730000 (China); Chen, Xingguo, E-mail: chenxg@lzu.edu.cn [National Key Laboratory of Organic Chemistry, Lanzhou University, Lanzhou 730000 (China); Department of Chemistry, Lanzhou University, Lanzhou 730000 (China)

2011-09-15

Highlights: {center_dot} Molecular docking revealed PAEs to be located in the hydrophobic pocket of HSA. {center_dot} HSA-DMP had one class of binding sites while HSA-BBP and HSA-DEHP had two types. {center_dot} Hydrophobic and hydrogen interactions dominated in the association of HSA-PAEs. {center_dot} The lifetime of Trp residue of HSA decreased after the addition of PAEs. {center_dot} The presences of PAEs could alter the second structure of HSA. - Abstract: Phthalate esters (PAEs) are globally pervasive contaminants that are considered to be endocrine disruptor chemicals and toxic environmental priority pollutants. In this paper, the interactions between PAEs and human serum albumin (HSA) were examined by molecular modelling, steady state and time-resolved fluorescence, ultraviolet-visible spectroscopy (UV-vis) and circular dichroism spectroscopy (CD). The association constants between PAEs and HSA were determined using the Stern-Volmer and Scatchard equations. The binding of dimethyl phthalate (DMP) to HSA has a single class of binding site and its binding constants (K) are 4.08 x 10{sup 3}, 3.97 x 10{sup 3}, 3.45 x 10{sup 3}, and 3.20 x 10{sup 3} L mol{sup -1} at 289, 296, 303, and 310 K, respectively. The Stern-Volmer and Scatchard plots both had two regression curves for HSA-butylbenzyl phthalate (BBP) and HSA-di-2-ethylhexyl phthalate (DEHP), which indicated that these bindings were via two types of binding sites: the numbers of binding site for the first type were lower than for the second type. The binding constants of the first type binding site were higher than those of the second type binding site at corresponding temperatures, the results suggesting that the first type of binding site had high affinity and the second binding site involved other sites with lower binding affinity and selectivity. The thermodynamic parameters of the binding reactions ({Delta}G{sup o}, {Delta}H{sup o} and {Delta}S{sup o}) were measured, and they indicated the presences

“… the ruins of Europe in back of me.” Jan Klata’s Shakespeare and the European condition

Directory of Open Access Journals (Sweden)

Cieślak Magdalena

2015-12-01

Full Text Available Jan Klata’s Shakespearean productions are famous for his liberal attitude to the text, innovative sets and locations, and a strong contemporary context. His 2004 H., a Teatr Wybrzeże production performed in the Gdańsk Shipyard, reaches to the Polish history of the eighties (the importance of Solidarity and the fall of communism to comment on the state of the democratic Poland twenty years later. The 2012 Titus Andronicus, a coproduction of Teatr Polski in Wrocław and Staatsschauspiel Dresden, explores the impact of historical traumas on national prejudice and relations within the new Europe. The 2013 Hamlet with Schauspielhaus Bochum again tries to diagnose the contemporary condition and is again deeply rooted in a specific geopolitical context.

Reminiscing about Jan Evangelista Purkinje: a pioneer of modern experimental physiology.

Science.gov (United States)

Cavero, Icilio; Guillon, Jean-Michel; Holzgrefe, Henry H

2017-12-01

This article reminisces about the life and key scientific achievements of Jan Evangelista Purkinje (1787-1869), a versatile 19th century Czech pioneer of modern experimental physiology. In 1804, after completing senior high school, Purkinje joined the Piarist monk order, but, after a 3-yr novitiate, he gave up the religious calling "to deal more freely with science." In 1818, he earned a Medical Doctor degree from Prague University by defending a dissertation on intraocular phenomena observed in oneself. In 1823, Purkinje became a Physiology and Pathology professor at the Prussian Medical University in Breslau, where he innovated the traditional teaching methods of physiology. Purkinje's contributions to physiology were manifold: accurate descriptions of various visual phenomena (e.g., Purkinje-Sanson images, Purkinje phenomenon), discovery of the terminal network of the cardiac conduction system (Purkinje fibers), identification of cerebellar neuronal bodies (Purkinje cells), formulation of the vertigo law (Purkinje's law), discovery of criteria to classify human fingerprints, etc. In 1850, Purkinje accepted and held until his death the Physiology chair at Prague Medical Faculty. During this period, he succeeded in introducing the Czech idiom (in addition to long-established German and Latin) as a Medical Faculty teaching language. Additionally, as a zealous Czech patriot, he actively contributed to the naissance and consolidation of a national Czech identity conscience. Purkinje was a trend-setting scientist who, throughout his career, worked to pave the way for the renovation of physiology from a speculative discipline, ancilla of anatomy, into a factual, autonomous science committed to the discovery of mechanisms governing in-life functions. Copyright © 2017 the American Physiological Society.

Tour of the stands at the UK@CERN industrial exhibition with the Director-General and H.E. Mr Simon Featherstone, HM Ambassador to Switzerland, hosted by Mrs. Jan Fillingham MBE, Head of Exhibitions, BEAMA

CERN Multimedia

Claudia Marcelloni

2006-01-01

Tour of the stands at the UK@CERN industrial exhibition with the Director-General and H.E. Mr Simon Featherstone, HM Ambassador to Switzerland, hosted by Mrs. Jan Fillingham MBE, Head of Exhibitions, BEAMA

Phthalate esters contamination in soil and plants on agricultural land near an electronic waste recycling site.

Science.gov (United States)

Ma, Ting Ting; Christie, Peter; Luo, Yong Ming; Teng, Ying

2013-08-01

The accumulation of phthalic acid esters (PAEs) in soil and plants in agricultural land near an electronic waste recycling site in east China has become a great threat to the neighboring environmental quality and human health. Soil and plant samples collected from land under different utilization, including fallow plots, vegetable plots, plots with alfalfa (Medicago sativa L.) as green manure, fallow plots under long-term flooding and fallow plots under alternating wet and dry periods, together with plant samples from relative plots were analyzed for six PAE compounds nominated as prior pollutants by USEPA. In the determined samples, the concentrations of six target PAE pollutants ranged from 0.31-2.39 mg/kg in soil to 1.81-5.77 mg/kg in various plants (dry weight/DW), and their bioconcentration factors (BCFs) ranged from 5.8 to 17.9. Health risk assessments were conducted on target PAEs, known as typical environmental estrogen analogs, based on their accumulation in the edible parts of vegetables. Preliminary risk assessment to human health from soil and daily vegetable intake indicated that DEHP may present a high-exposure risk on all ages of the population in the area by soil ingestion or vegetable consumption. The potential damage that the target PAE compounds may pose to human health should be taken into account in further comprehensive risk assessments in e-waste recycling sites areas. Moreover, alfalfa removed substantial amounts of PAEs from the soil, and its use can be considered a good strategy for in situ remediation of PAEs.

Mineralogy and Geochemistry from Trollveggen Vent Field Chimneys and Metalliferous Sediments (Mohns Ridge, West Jan Mayen Fracture Zone at 71°N)

Science.gov (United States)

Dias, S.; Cruz, I.; Fonseca, R.; Barriga, F. J.; Pedersen, R.

2010-12-01

The Jan Mayen vent fields were discovered in the Mohns Ridge during an expedition with the Norwegian research vessel "G.O. Sars" in July 2005. They comprise two main active areas: (1) Soria Moria and (2) Gallionella Garden & Trollveggen. The Trollveggen vent field is located at depths of 700-750 m. Venting takes place mainly through white smoker chimneys with fluid temperatures reaching up to 260-270°C. Here we present mineralogical and geochemical data from vent chimneys and metalliferous sediments collected at the Trollveggen vent field with an ROV. Cross-sections of chimneys present evident mineralogical zonation, showing acicular barite crystals in the outer parts and sulfide enrichments in the interior (Sph + Cpy +/- Py - Po). Sediments are mainly formed by vent fragments but also by minerals precipitated by diffuse fluid circulation, showing a mineral assemblage similar to that of chimneys. Microprobe analyses were obtained both in sulfates and sulphides revealing a particular sphalerite composition, characterized by low Fe (< 2%) and high total trace metal contents (up to 4%, including Cu, Ag and Au). Geochemical profiles of gravity cores collected in the area surrounding Jan Mayen were also performed in order to investigate the presence of additional hydrothermal activity in the area. Total geochemical analyses showed a slight enrichment in trace metals, such as Cu, Zn and Fe, with exception of one core that reached 85 ppm for Cu, 150 ppm for Zn and 20% for Fe. The metal enrichment in this core suggests hydrothermal activity in the neighboring area.

Integrated Advanced Microwave Sounding Unit-A (AMSU-A). Engineering Test Report: AMSU-A2 METSAT Instrument (S/N 108) Acceptance Level Vibration Tests of Dec 1999/Jan 2000 (S/O 784077, OC-454)

Science.gov (United States)

Heffner, R.

2000-01-01

This is the Engineering Test Report, AMSU-A2 METSAT Instrument (S/N 108) Acceptance Level Vibration Test of Dec 1999/Jan 2000 (S/O 784077, OC-454), for the Integrated Advanced Microwave Sounding Unit-A (AMSU-A).

In vitro assessment of phthalate acid esters-trypsin complex formation.

Science.gov (United States)

Chi, Zhenxing; Zhao, Jing; Li, Weiguo; Araghi, Arash; Tan, Songwen

2017-10-01

In this work, interactions of three phthalate acid esters (PAEs), including dimethyl phthalate (DMP), diethyl phthalate (DEP) and dibutyl phthalate (DBP), with trypsin have been studied in vitro, under simulated physiological conditions using multi-spectroscopic techniques and molecular modeling. The results show that these PAEs can bind to the trypsin, forming trypsin-PAEs complexes, mainly via hydrophobic interactions, with the affinity order of DMP > DEP > DBP. Binding to the PAEs is found to result in molecular deformation of trypsin. The modeling results suggest that only DBP can bind with the amino acid residues of the catalytic triad and S1 binding pocket of trypsin, leading to potential competitive enzyme inhibition. Copyright © 2017 Elsevier Ltd. All rights reserved.

Pharmacodynamics of beta-lactam antibiotics. Studies on the paradoxical and postantibiotic effects in vitro and in an animal model.

Science.gov (United States)

Odenholt-Tornqvist, I

1989-01-01

The pharmacodynamics of antibiotics, i.e. the rate of killing and the time before regrowth of surviving bacteria, may be important factors for determination of the dosage interval. In the present study the effect of protein binding, antibiotic concentrations, bacterial growth phase and bacterial inoculum on the rate of bacterial killing was investigated. The postantibiotic effect (PAE) was also studied in vitro and in vivo. The killing rate of S. aureus did not differ when the bacteria were exposed to the same free concentrations of dicloxacillin in medium with and without albumin. Protein binding per se did thus not diminish the bactericidal activity. A paradoxically reduced bactericidal effect was noted when S. aureus was exposed to high concentrations of dicloxacillin, cloxacillin and benzylpenicillin. For determination of PAE of imipenem on Ps. aeruginosa, counts of viable bacteria were compared with assay of bacterial intracellular ATP. Both methods demonstrated a PAE for the strains tested at an inoculum of 10(6) cfu/ml. At an inoculum of 10(8) cfu/ml no PAE was found, which coincided with a lack of bactericidal effect. Both the PAE and the bactericidal effect were restored with aeration of the cultures, indicating insufficient penetration of imipenem to the target sites at low oxygen tension. An in vivo model in rabbits with implanted tissue cages was developed for evaluation of the PAE. Group A beta-hemolytic streptococci showed a PAE of approximately 2 h in vivo, which correlated well with the PAE found in vitro. Despite that streptococci in postantibiotic phase (PA-phase) were non-multiplying, such bacteria were killed as efficiently as previously untreated controls when exposed to 10xMIC of penicillin both in vitro and in vivo. However, streptococci in PA-phase were much more sensitive to the repeated challenge to subinhibitory concentrations of penicillin than previously untreated controls. In vivo, no difference in sensitivity to sub-MIC penicillin

Reductions in Corpus Callosum Volume Partially Mediate Effects of Prenatal Alcohol Exposure on IQ

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Stevie C. Biffen

2018-01-01

Full Text Available Disproportionate volume reductions in the basal ganglia, corpus callosum (CC and hippocampus have been reported in children with prenatal alcohol exposure (PAE. However, few studies have investigated these reductions in high prevalence communities, such as the Western Cape Province of South Africa, and only one study made use of manual tracing, the gold standard of volumetric analysis. The present study examined the effects of PAE on subcortical neuroanatomy using manual tracing and the relation of volumetric reductions in these regions to IQ and performance on the California Verbal Learning Test-Children's Version (CVLT-C, a list learning task sensitive to PAE. High-resolution T1-weighted images were acquired, using a sequence optimized for morphometric neuroanatomical analysis, on a Siemens 3T Allegra MRI scanner from 71 right-handed, 9- to 11-year-old children [9 fetal alcohol syndrome (FAS, 19 partial FAS (PFAS, 24 non-syndromal heavily exposed (HE and 19 non-exposed controls]. Frequency of maternal drinking was ascertained prospectively during pregnancy using timeline follow-back interviews. PAE was examined in relation to volumes of the CC and left and right caudate nuclei, nucleus accumbens and hippocampi. All structures were manually traced using Multitracer. Higher levels of PAE were associated with reductions in CC volume after adjustment for TIV. Although the effect of PAE on CC was confounded with smoking and lead exposure, additional analyses showed that it was not accounted for by these exposures. Amongst dysmorphic children, smaller CC was associated with poorer IQ and CVLT-C scores and statistically mediated the effect of PAE on IQ. In addition, higher levels of PAE were associated with bilateral volume reductions in caudate nuclei and hippocampi, effects that remained significant after control for TIV, child sex and age, socioeconomic status, maternal smoking during pregnancy, and childhood lead exposure. These data confirm

A Campaign of the Great Hetman Jan Zamoyski in Moldavia (1595. Part I. Politico-diplomatic and military preliminaries

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Dariusz Milewski

2012-12-01

Full Text Available Polish-Turkish relations in the sixteenth century were generally peaceful, but the source of a conflict remained because of recurring bouts of Tatars and Cossacks, and the unexpired Polish claims to sovereignty over Moldavia. The outbreak of the war between the Ottomans and the Habsburgs in 1593 offered for Poland an opportunity to strengthen its policy in the southeast. The movement of the Christian vassals of the Sultan to the side of the Emperor Rudolf II resulted in the relocation of military operations to the territory of today’s Romania. The subordination of the Romanian lands to the Habsburgs or their complete subjugation by the Ottomans was dangerous to Rzeczpospolita. Thus, in the summer of 1595, the Chancellor and the Great Hetman of the Crown Jan Zamoyski decided to enter with a part of Polish troops to Moldavia.

Caudate Asymmetry: A Neurobiological Marker of Moderate Prenatal Alcohol Exposure in Young Adults

OpenAIRE

Willford, Jennifer; Day, Richard; Aizenstein, Howard; Day, Nancy

2010-01-01

This study identified structural changes in the caudate nucleus in offspring of mothers who drank moderate levels of alcohol during pregnancy. In addition, the effect of duration of alcohol use during pregnancy was assessed. Young adults were recruited from the Maternal Health Practices and Child Development Project. Three groups were evaluated: prenatal alcohol exposure (PAE) during all three trimesters (3T), PAE during the first trimester only (1T), and controls with no PAE (0T). Magnetic r...

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2010-05-01

Full Text Available Diretora Geral Cibele Daher Botelho Monteiro Vice-Diretora Geral Jefferson Manhães de Azevedo Coordenadora de Pós-Graduação Vera Raimunda Amério Asseff Coordenador de Pesquisa Rogério Atem de Carvalho Editora-Chefe Maria Amelia Ayd Correa Coordenação Editorial do Boletim Maria Inês Paes Ferreira Conselho Editorial Dalila Silva MelloMarcos Antonio Cruz MoreiraRoberta de Sousa RamalhoVicente de Paulo Santos de Oliveira Organizadores deste número Maria Inês Paes FerreiraMariana Rodrigues de Carvalhaes PinheiroTathiana Chaves de Souza Apoio Técnico Gisele Carvalho da Silva Costa NogueiraCarlos David Pasco Bolsistas de Iniciação Científica Felipe Eliakim SilvaSamara Melo Rodrigues Revisão de Texto Edinalda Maria Almeida da Silva Projeto Gráfico André da Silva CruzDaniel Marques Sardinha Diagramação Daniel Marques Sardinha Capa Daniel Marques Sardinha Revisão Técnica Flávia Gomes de Abreu SiqueiraVanessa Vasconcelos Lopes Assistente de Editoração Cláudia de Souza Caetano Catalogação Antonio Soares das Chagas Filho Dados de Catalogação na Publicação (CIP Boletim do Observatório Ambiental Alberto Ribeiro Lamego. - Vol. 2, n. 1 (jan./jun. 2008. Centro Federal de Educação Tecnológicade Campos. Observatório Ambiental Alberto Ribeiro Lamego.Campos dos Goytacazes, RJ: Essentia Editora, 2008 - v. : il. 14 cm. SemestralISSN 1981-6197 1. Engenharia ambiental. I. Centro Federal de Educação Tecnológicade Campos. II. Observatório Ambiental Alberto Ribeiro Lamego. CDD - 628 Tiragem: 1000 exemplaresImpressão: Gráfica e Editora GSA | Tel.: (27 3232-1266

Three Giants in the Cradle of Reproductive Medicine; Reproduction Theories of the Seventeenth Century as Discerned by Pregnancy Portraiture in the Oeuvre of Jan Vermeer

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Ronit Haimov-Kochman

2016-04-01

Full Text Available Portraits of pregnant women are rare in Catholic Renaissance art. In seventeenth-century Holland, the Catholic rule of Spain had been thrown off and a Protestant Calvinistic republic emerged, freeing Dutch artists to choose an unorthodox subject matter for their paintings. The Golden Age of Holland was characterized by extreme wealth, originating from overseas trade, which fostered a marked interest in philosophy, science, medicine, as well as art. Despite this, portraiture of pregnancy remained uncommon. An exception to this rule was Jan Vermeer of Delft, who lived during the zenith of this era. Jan Vermeer painted fewer than 40 pictures, fathered 15 children, and died bankrupt and little appreciated at the age of 43. Vermeer confined himself almost entirely to images of women in various domestic situations, including three figures of pregnant women. In this framework, pregnancy could be viewed as an icon for fidelity and conformism to social expectations. In this paper we investigate the roots of this unusual icon in Vermeer’s oeuvre, and suggest that the use of pregnancy in his paintings could have been inspired by his Delft-resident contemporaries Antony van Leeuwenhoek and Reinier de Graaf, fathers of well-known and opposing theories of reproduction. These eminent scientists and Vermeer’s pregnant wife, who frequently served as his model, might have made pregnancy less mysterious and more realistic to the painter.

[Determination of total phthalates in perfume and their exposure assessment].

Science.gov (United States)

Zhao, Sihan; Wang, Zhengmeng; Deng, Hongxia; Duan, Jiahui; Wang, Jinyi; Liu, Shuhui

2017-12-08

A novel method for rapid screening of phthalates (PAEs) in perfumes was developed. The PAEs were hydrolyzed to phthalic acid (PA), and the PA in the acidified solution was extracted with tributyl phosphate (TBP) which was detected by high performance liquid chromatography-diode array detection (HPLC-DAD). Meanwhile exposure dose to PAEs was estimated by the percentage of a topically applied dose that permeates the skin. The parameters such as the concentration and volume of KOH, the volume of ethanol, hydrolysis time and temperature were employed to evaluate the hydrolysis efficiency of PAEs. The optimized hydrolysis conditions were 10 mL of 4 mol/L KOH, and 1 mL of ethanol at 80℃ for 20 min. The linear range of phthalic acid was 3-240 μmol/L with a good correlation coefficient ( R 2 =0.9991). The limits of detection (LOD) and quantification (LOQ) were 4.6 μmol/kg and 5.9 μmol/kg, respectively. The recoveries varied from 83.4% to 92.7% with relative standard deviations equal to or lower than 6.8%( n =5). A total of 35 perfume samples were determined, and the contents of total PAEs were found in the range of perfumes. The method is simple and reliable, and has a wide range of applicability. It can be used as a new choice for the detection of PAEs in perfume.

Pneumatized articular eminence in a cohort of orthodontic patients with different sagittal skeletal anomalies. A retrospective cone beam computed tomography study

International Nuclear Information System (INIS)

Miloglu, O.; Celikoglu, M.; Yildirim, E.; Yilmaz, A.B.; Demirtas, O.

2010-01-01

The aim of this study was to determine the prevalence and characteristics of pneumatized articular eminence (PAE) in dental patients using cone beam computed tomography (CBCT) with respect to age, sex, and type of skeletal anomaly. The results were then compared to prevalence studies regarding PAE in the literature. A retrospective study of 603 orthodontic patients aged between 6 and 24 years was performed using sagittal and coronal CBCT images at the Department of Oral and Maxillofacial Radiology (Erzurum, Turkey). The age, gender, skeletal anomaly, and lateral were recorded for all patients, and the types were noted for cases of PAE. The chi-squared test was used for statistical analyses. Sixty-four PAEs were found in 39 orthodontic patients, representing a prevalence of 6.47%. No significant differences in sex (p=0.153), age (before and after puberty, p=0.389), and type of skeletal anomaly were observed (p=0.271). A higher frequency of PAE was detected among dental patients aged 6-24 years when compared to previous studies, most likely because of the use of CBCT images. No significant relation was observed between PAE and the type of skeletal anomalies. One, however, must be aware of these structures to avoid complications in cases for which surgical treatment is planned due to the occlusion and recognize its role in the onset or perpetuation of temporomandibular joint dysfunction. (author)

Aminoglycoside-derived amphiphilic nanoparticles for molecular delivery.

Science.gov (United States)

Miryala, Bhavani; Godeshala, Sudhakar; Grandhi, Taraka Sai Pavan; Christensen, Matthew D; Tian, Yanqing; Rege, Kaushal

2016-10-01

The development of effective drug carriers can lead to improved outcomes in a variety of disease conditions. Aminoglycosides have been used as antibacterial therapeutics, and are attractive as monomers for the development of polymeric materials in various applications. Here, we describe the development of novel aminoglycoside-derived amphiphilic nanoparticles for drug delivery, with an eye towards ablation of cancer cells. The aminoglycoside paromomycin was first cross-linked with resorcinol diglycidyl ether leading to the formation of a poly (amino ether), PAE. PAE molecules were further derivatized with methoxy-terminated poly(ethylene glycol) or mPEG resulting in the formation of mPEG-PAE polymer, which self-assembled to form nanoparticles. Formation of the mPEG-PAE amphiphile was characterized using (1)H NMR, (13)C NMR, gel permeation chromatography (GPC) and FTIR spectroscopy. Self-assembly of the polymer into nanoparticles was characterized using dynamic light scattering, zeta potential analyses, atomic force microscopy (AFM) and the pyrene fluorescence assay. mPEG-PAE nanoparticles were able to carry significant amounts of doxorubicin (DOX), presumably by means of hydrophobic interactions between the drug and the core. Cell-based studies indicated that mPEG-PAE nanoparticles, loaded with doxorubicin, were able to induce significant loss in viabilities of PC3 human prostate cancer, MDA-MB-231 human breast cancer, and MB49 murine bladder cancer cells; empty nanoparticles resulted in negligible losses of cell viability under the conditions investigated. Taken together, our results indicate that the mPEG-PAE nanoparticle platform is attractive for drug delivery in different applications, including cancer. Copyright © 2016 Elsevier B.V. All rights reserved.

The Oswestry Disability Index, the Roland-Morris Disability Questionnaire, and the Quebec Back Pain Disability Scale: translation and validation studies of the Iranian versions.

Science.gov (United States)

Mousavi, Sayed Javad; Parnianpour, Mohamad; Mehdian, Hossein; Montazeri, Ali; Mobini, Bahram

2006-06-15

Cross-cultural translation and psychometric testing were performed. To cross-culturally translate the Oswestry Disability Index (ODI), Roland-Morris Disability Questionnaire (RDQ), and Quebec Back Pain Disability Scale (QDS) into Persian, and then investigate the psychometric properties of the Persian versions produced. To the authors' knowledge, there is no validated instrument to measure functional status in Persian-speaking patients with low back pain (LBP) in Iran. To our knowledge, the widely used back-specific measures, the ODI, RDQ, and QDS, have not been translated and validated for Persian-speaking patients with LBP. The translation and cross-cultural adaptation of the original questionnaires were performed in accordance with published guidelines. A total of 100 patients with chronic LBP were asked to complete a questionnaire booklet (the Persian versions of the ODI, RDQ, QDS, Short Form Health Survey (SF-36), and visual analog scale measure of pain). There were 31 randomly select patients with chronic LBP asked to complete the second questionnaire booklet 24 hours later. The Cronbach-alpha for the ODI, RDQ, and QDS was 0.75, 0.83, and 0.92, respectively. The ODI, RDQ, and QDS showed excellent test-retest reliability (intraclass correlation coefficient = 0.91, 0.86, and 0.86, respectively) (P < 0.01). The correlation among the ODI, RDQ, QDS and physical functioning scales of the SF-36 was -0.66, -0.62, and -0.69, respectively (P < 0.001). The correlation among the ODI, RDQ, and QDS and visual analog scale was 0.54, 0.36, and 0.46, respectively (P < 0.001). The Persian versions of the ODI, RDQ, and QDS are reliable and valid instruments to measure functional status in Persian-speaking patients with LBP. They are simple and fast scales, and the use of them can be recommended in a clinical setting and future outcome studies in Iran.

AlGaN/GaN-HEMT power amplifiers with optimized power-added efficiency for X-band applications

OpenAIRE

Kühn, J.

2011-01-01

This work has arisen out of the strong demand for a superior power-added efficiency (PAE) of AlGaN/GaN high electron mobility transistor (HEMT) high-power amplifiers (HPAs) that are part of any advanced wireless multifunctional RF-system with limited prime energy. Different concepts and approaches on device and design level for PAE improvements are analyzed, e.g. structural and layout changes of the GaN transistor and advanced circuit design techniques for PAE improvements of GaN HEMT HPAs.

Plaadid / Immo Mihkelson

Index Scriptorium Estoniae

Mihkelson, Immo, 1959-

2002-01-01

Uutest plaatidest Robert Plant "Dreamfield", Roland Gift "Roland Gift", Joe Cocker "Respect Yourself", Piano Circus "Transmission", Tricky "A Ruff Guide", Jack Johnson "Brushfire Fairytales", Yann Tiersen "Amelie from Montmartre", Hall & Oates "The Essential Collection"

Roland Barthes' "Text" and aleatoric music: Is "The birth of the reader" the birth of the listener?

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Jeongwon Joe

2002-01-01

Full Text Available The history of Western classical music and the development of its notational system show that composers have tried to control more and more aspects of their compositions as precisely as possible. Total serialism represents the culmination of compositional control. Given this progressively increasing compositional control, the emergence of chance music, or aleatoric music, in the mid-twentieth century is a significantly interesting phenomenon. In aleatoric music, the composer deliberately incorporates elements of chance in the process of composition and/or in performance. Consequently, aleatoric works challenge the traditional notion of an art work as a closed entity fixed by its author. The philosophical root of aleatoric music can be traced to post structuralism, specifically its critique of the Enlightenment notion of the author as the creator of the meaning of his or her work. Roland Barthes' declaration of "the death of the author" epitomizes the Poststructuralists' position. Distinguishing "Text" from "Work," Barthes maintains that in a "Text," meanings are to be engendered not by the author but by the reader. Barthes conceives aleatoric music as an example of the "Text," which demands "the birth of the reader." This essay critically re-examines Barthes' notion of aleatoric music, focusing on the complicated status of the reader in music. The readers of a musical Text can be both performers and listeners. When Barthes' declaration of the birth of the reader is applied to the listener, it becomes problematic, since the listener, unlike the literary reader, does not have direct access to the "Text" but needs to be mediated by the performer. As Carl Dahlhaus has remarked, listeners cannot be exposed to other possible renditions that the performer could have chosen but did not choose, and in this respect, the supposed openness of an aleatoric piece is closed and fixed at the time of performance. In aleatoric music, it is not listeners but only

Jan Patočka: fenomenología asubjetiva y filosofía herética de la Historia

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Ortega Rodríguez, Iván

2009-04-01

Full Text Available Our aim is to present the thought of Jan Patočka and the philosophical debates stimulated by his positions. The core of his thought is, on our opinion, human existence as essentially transcending the given and disclosing its essential freedom. Patočka’s phenomenological research seeks an “asubjective phenomenology” and a conceptualization of existence as movement (diversified in the three movements of human existence. In Philosophy of History, Patočka focuses on the origins of Europe and at the essential transformations which have led to an absolute dominion of technical reason. In this situation, only sacrifice seems to offer a possibility to counter the absoluteness of technical civilisation. Finally, we confront Patočka and Lévinas, and we show that a fundamental debate between ontological pluralism and ontological monism is stirred. This debate is of essential importance in the fields of Ethics and Politics. Patočka’s thought is, then, an example of how phenomenology is still timely.Nuestro objetivo es presentar el pensamiento de Jan Patočka y los debates filosóficos que suscitan sus posiciones. El núcleo de su pensamiento, a nuestro juicio, es la existencia humana como esencialmente trascendiendo lo dado y descubriendo en ello su esencial libertad. La investigación fenomenológica de Patočka busca una fenomenología “asubjetiva” y conceptuar la existencia como movimiento (diversificado en los tres movimientos de la existencia humana. La filosofía de la historia apunta a los orígenes de Europa, así como a las transformaciones esenciales que han llevado a un dominio absoluto de la razón técnica. En esta situación, sólo el sacrificio parece poder contrarrestar la civilización técnica. Finalmente, confrontamos a Patočka con Levinas, mostrando cómo se suscita un debate fundamental entre el monismo y el pluralismo ontológico. Este debate tiene una importancia crucial la Ética y la Política El pensamiento de

The imagination of touch: surrealist tactility in the films of Jan Švankmajer

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Kristoffer Noheden

2013-09-01

Full Text Available This article is a theoretical examination of tactility in the Czech surrealist filmmaker Jan Švankmajer's film Down to the Cellar (1983. Švankmajer's deployment of tactile images in a surrealist context shows the need for a discussion of the imagination's role in the embodied film experience. Departing from Laura Marks's The Skin of the Film, this article seeks to explore the surrealist embodied imagination through surrealist poetics of analogy, as defined by André Breton, and the link between these and Walter Benjamin's writings on mimesis. Finally, the film is viewed from the perspective of Gaston Bachelard's ideas of “the imagination of matter,” where matter is seen as a highly potent stimulant for the imagination. Bachelard's notion of the imagination's multisensory properties further lends credence to Švankmajer's aims to liberate the imagination of the spectator through images that invoke touch. Kristoffer Noheden is a PhD candidate in cinema studies at the Department of Media Studies, Stockholm University. In his dissertation, he examines surrealism's attempts to create a new, re-enchanting myth with a focus on its expressions in surrealist cinema. He is the co-editor, with Daniel Brodén, of the anthology I gränslandet: Nya perspektiv på film och modernism (Gidlunds, 2013. He is also the translator into Swedish of books by William S. Burroughs, Leonora Carrington, Max Ernst, and others, and co-runs the surrealist-oriented publishing house Sphinx.

Rolandic epilepsy and dyslexia

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Ecila P. Oliveira

2014-11-01

Full Text Available Objective Although benign epilepsy with centrotemporal spikes (BECTS is an idiopathic, age-related epilepsy syndrome with favorable outcome, recent studies have shown impairment in specific neuropsychological tests. The objective of this study was to analyze the comorbidity between dyslexia and BECTS. Method Thirty-one patients with clinical and electroencephalographic diagnosis of BECTS (group A and 31 paired children (group B underwent a language and neuropsychological assessment performed with several standardized protocols. Our findings were categorized as: a dyslexia; b other difficulties; c without difficulties. Our results were compared and statistically analyzed. Results Our data showed that dyslexia occurred in 19.4% and other difficulties in 74.2% of our patients. This was highly significant when compared with the control group (p<0.001. Phonological awareness, writing, reading, arithmetic, and memory tests showed a statistically significant difference when comparing both groups. Conclusion Our findings show significant evidence of the occurrence of dyslexia in patients with BECTS.

Roland Weber second part

DEFF Research Database (Denmark)

2016-01-01

Biodiversity of storage rot in Denmark and Northern Germany. A new look at Hot-Water treatments of apples.......Biodiversity of storage rot in Denmark and Northern Germany. A new look at Hot-Water treatments of apples....

Roland Weber first part

DEFF Research Database (Denmark)

2016-01-01

The Sooty bloch complex - species identity, infection biology and control options. Rubbery rot and Black summer rot - two new diseases of apple......The Sooty bloch complex - species identity, infection biology and control options. Rubbery rot and Black summer rot - two new diseases of apple...

Safety and Efficacy of Occlusion of Large Extra-Prostatic Anastomoses During Prostatic Artery Embolization for Symptomatic BPH

Energy Technology Data Exchange (ETDEWEB)

Amouyal, Gregory, E-mail: gregamouyal@hotmail.com; Chague, Pierre, E-mail: pierre.chague@gmail.com; Pellerin, Olivier, E-mail: olivier.pellerin@aphp.fr [Université Paris Descartes - Sorbonne - Paris – Cité, Faculté de Médecine (France); Pereira, Helena, E-mail: helena.pereira@aphp.fr [Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Clinical Research Unit (France); Giudice, Costantino Del, E-mail: costantino.delgiudice@aphp.fr [Université Paris Descartes - Sorbonne - Paris – Cité, Faculté de Médecine (France); Dean, Carole, E-mail: carole.dean@aphp.fr [Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Interventional Radiology Department (France); Thiounn, Nicolas, E-mail: nicolas.thiounn@aphp.fr; Sapoval, Marc, E-mail: marc.sapoval2@aphp.fr [Université Paris Descartes - Sorbonne - Paris – Cité, Faculté de Médecine (France)

2016-09-15

IntroductionDuring PAE, preembolization angiography of the prostatic artery can show large extra-prostatic shunts, at high risk, if embolized, of rectal or penile necrosis. We report our experience with 11 consecutive patients who underwent protective embolization of large extra-prostatic shunts before successful PAE.Materials and MethodsWe treated 11 consecutive male patients (mean age 67 years), part of a series of 55 consecutive male patients referred for PAE to treat LUTS due to BPH, between December 2013 and January 2015. The procedure involved the exclusion of an extra-prostatic shunt originating from the PA, prior to complete bilateral PAE. We compared the safety and efficacy of the 11 shunt exclusions followed by embolization of the PA to the other 44 basic PAE. Clinical success was defined as a decrease of 25 % or eight points of IPSS, QoL <3 or a one-point decrease, and a Qmax improvement of 25 % or 2.5 mL/s.ResultsWe had a 100 % rate of occlusion of the anastomosis. Bilateral embolization of the PA was performed in all patients with no additional time of procedure (p = 0.18), but a significant increase of dose area product (p = 0.03). Distal (PErFecTED) embolization was possible in 64 %. There was no worsening of erectile dysfunction, no rectal or penile necrosis, no immediate or late other clinical complications. Clinical success was 91 % (mean follow-up: 3.5 months), compared to 78 % for the entire PAE group.ConclusionPAE using the protection technique in case of large extra-prostatic shunts is as safe and effective as basic procedures and does not induce any additional time of procedure.

Safety and Efficacy of Occlusion of Large Extra-Prostatic Anastomoses During Prostatic Artery Embolization for Symptomatic BPH

International Nuclear Information System (INIS)

Amouyal, Gregory; Chague, Pierre; Pellerin, Olivier; Pereira, Helena; Giudice, Costantino Del; Dean, Carole; Thiounn, Nicolas; Sapoval, Marc

2016-01-01

IntroductionDuring PAE, preembolization angiography of the prostatic artery can show large extra-prostatic shunts, at high risk, if embolized, of rectal or penile necrosis. We report our experience with 11 consecutive patients who underwent protective embolization of large extra-prostatic shunts before successful PAE.Materials and MethodsWe treated 11 consecutive male patients (mean age 67 years), part of a series of 55 consecutive male patients referred for PAE to treat LUTS due to BPH, between December 2013 and January 2015. The procedure involved the exclusion of an extra-prostatic shunt originating from the PA, prior to complete bilateral PAE. We compared the safety and efficacy of the 11 shunt exclusions followed by embolization of the PA to the other 44 basic PAE. Clinical success was defined as a decrease of 25 % or eight points of IPSS, QoL <3 or a one-point decrease, and a Qmax improvement of 25 % or 2.5 mL/s.ResultsWe had a 100 % rate of occlusion of the anastomosis. Bilateral embolization of the PA was performed in all patients with no additional time of procedure (p = 0.18), but a significant increase of dose area product (p = 0.03). Distal (PErFecTED) embolization was possible in 64 %. There was no worsening of erectile dysfunction, no rectal or penile necrosis, no immediate or late other clinical complications. Clinical success was 91 % (mean follow-up: 3.5 months), compared to 78 % for the entire PAE group.ConclusionPAE using the protection technique in case of large extra-prostatic shunts is as safe and effective as basic procedures and does not induce any additional time of procedure.

Predictors of the success and failure of emergency pelvic artery embolisation for primary postpartum haemorrhage: a 12-year review.

Science.gov (United States)

Lai, Billy Ming Hei; Shum, John Sing Fai; Chu, Chi Yeung; Lo, Sherwin Shing Wai; Lau, Kam Ying

2017-05-01

This study aimed to identify predictors of the outcome and clinical efficacy of emergency pelvic artery embolisation (PAE) for primary postpartum haemorrhage (PPH) and to assess the post-embolisation fertility of PAE patients in a regional hospital setting. A 12-year retrospective study of patients undergoing emergency PAE was conducted at a regional acute general hospital. Clinical and procedural parameters, clinical outcomes and post-embolisation pregnancy success rates were analysed. There were 47,221 deliveries at the hospital during the study period, of which 33 patients required urgent PAE for primary PPH. The technical success rate of embolisation was 97.0% (n = 32). Clinically adequate haemostasis was achieved by a single embolisation procedure in 24 (72.7%) patients; the remaining eight eventually required surgery to achieve cessation of bleeding. Among the parameters studied, multivariate logistic regression analysis showed that pre-embolisation platelet count (p = 0.036) and maternal age (p = 0.019) were the only significant independent predictors of embolisation failure. Only two patients successfully conceived after PAE, although one of them had an ectopic pregnancy. Emergency PAE is an effective measure to arrest life-threatening bleeding in patients with primary PPH. As low pre-embolisation platelet count and advanced maternal age are associated with higher odds of embolisation failure, careful post-embolisation monitoring may be required for such patients. Embolisation also allows subsequent pregnancy. However, further studies are required to assess the outcomes of post-embolisation pregnancies. Copyright: © Singapore Medical Association

Characterization of Polyethylene-Graft-Sulfonated Polyarylsulfone Proton Exchange Membranes for Direct Methanol Fuel Cell Applications.

Science.gov (United States)

Kim, Hyung Kyu; Zhang, Gang; Nam, Changwoo; Chung, T C Mike

2015-12-04

This paper examines polymer film morphology and several important properties of polyethylene-graft-sulfonated polyarylene ether sulfone (PE-g-s-PAES) proton exchange membranes (PEMs) for direct methanol fuel cell applications. Due to the extreme surface energy differences between a semi-crystalline and hydrophobic PE backbone and several amorphous and hydrophilic s-PAES side chains, the PE-g-s-PAES membrane self-assembles into a unique morphology, with many proton conductive s-PAES channels embedded in the stable and tough PE matrix and a thin hydrophobic PE layer spontaneously formed on the membrane surfaces. In the bulk, these membranes show good mechanical properties (tensile strength >30 MPa, Young's modulus >1400 MPa) and low water swelling (λ 3 mmol/g in the s-PAES domains. On the surface, the thin hydrophobic and semi-crystalline PE layer shows some unusual barrier (protective) properties. In addition to exhibiting higher through-plane conductivity (up to 160 mS/cm) than in-plane conductivity, the PE surface layer minimizes methanol cross-over from anode to cathode with reduced fuel loss, and stops the HO• and HO₂• radicals, originally formed at the anode, entering into PEM matrix. Evidently, the thin PE surface layer provides a highly desirable protecting layer for PEMs to reduce fuel loss and increase chemical stability. Overall, the newly developed PE-g-s-PAES membranes offer a desirable set of PEM properties, including conductivity, selectivity, mechanical strength, stability, and cost-effectiveness for direct methanol fuel cell applications.

Fast microextraction of phthalate acid esters from beverage, environmental water and perfume samples by magnetic multi-walled carbon nanotubes.

Science.gov (United States)

Luo, Yan-Bo; Yu, Qiong-Wei; Yuan, Bi-Feng; Feng, Yu-Qi

2012-02-15

In this work, magnetic carbon nanotubes (CNTs) were prepared by mixing the magnetic particles and multi-walled carbon nanotubes dispersed solutions. Due to their excellent adsorption capability towards hydrophobic compounds, the magnetic CNTs were used as adsorbent of magnetic solid-phase extraction (MSPE) to extract phthalate acid esters (PAEs), which are widely used in many consumable products with potential carcinogenic properties. By coupling MSPE with gas chromatography/mass spectrometry (GC/MS), a rapid, sensitive and cost-effective method for the analysis of PAEs was established. Our results showed that the limits of detection (LODs) of 16 PAEs ranged from 4.9 to 38 ng L(-1), which are much lower compared to the previously reported methods. And good linearities of the detection method were obtained with correlation coefficients (R(2)) between 0.9821 and 0.9993. In addition, a satisfying reproducibility was achieved by evaluating the intra- and inter-day precisions with relative standard deviations (RSDs) less than 11.7% and 14.6%, respectively. Finally, the established MSPE-GC/MS method was successfully applied to the determination of PAEs from bottled beverages, tap water and perfume samples. The recoveries of the 16 PAEs from the real samples ranged from 64.6% to 125.6% with the RSDs less than 16.5%. Taken together, the MSPE-GC/MS method developed in current study provides a new option for the detection of PAEs from real samples with complex matrices. Copyright © 2012 Elsevier B.V. All rights reserved.

Adolescents' use of alcohol, tobacco and illicit drugs in relation to prenatal alcohol exposure: modifications by gender and ethnicity.

Science.gov (United States)

Pfinder, Manuela; Liebig, Stefan; Feldmann, Reinhold

2014-01-01

The study aimed to investigate (a) the association between low to moderate prenatal alcohol exposure (PAE) and the use of alcohol, tobacco and illicit drugs in adolescence and (b) whether the associations are modified by gender and ethnicity. The subjects of the study were 5922 children and adolescents, aged from 11 to 17 years, enrolled in the cross-sectional German Health Interview and Examination Survey for Children and Adolescents (the KiGGS study). Information on PAE is based on parental self-report questionnaires. Use of alcohol, tobacco and illicit drugs was assessed through self-report questionnaires for adolescents. Low to moderate PAE was associated with an increased risk of drinking alcohol (adjusted odds ratio (OR) 1.73, 95% confidence interval (CI) 1.34, 2.18) and also of illicit drug use (adjusted OR 1.62, 95% CI 1.23, 2.14). The associations between PAE and the use of alcohol, tobacco and illicit drugs differed according to gender and ethnicity. Gender-stratified analyses resulted in adverse effects of PAE on drinking alcohol, smoking and illicit drug use in females; however, in German males, the associations disappeared. Stronger associations between PAE and the outcome measures were found in non-Germans. Our findings indicate that low to moderate levels of maternal alcohol intake during pregnancy are a risk factor for use of alcohol, tobacco and illicit drugs by the offspring, with stronger associations in females and non-Germans.

High-resolution MR imaging of periarterial edema associated with biological inflammation in spontaneous carotid dissection

Energy Technology Data Exchange (ETDEWEB)

Naggara, Olivier; Marsico, Rodolpho; Meder, Jean-Francois; Oppenheim, Catherine [Paris-Descartes University, Department of Neuroradiology, Paris (France); Touze, Emmanuel; Mas, Jean-Louis [Paris-Descartes University, Department of Neurology, Paris (France); Leclerc, Xavier; Pruvo, Jean-Pierre [University Hospital Roger Salengro, Department of Neuroradiology, Lille (France); Nguyen, Thanh [Boston University Medical Center, Department of Neurology, Neurosurgery, and Radiology, Boston, MA (United States)

2009-09-15

It has been suggested that spontaneous cervical carotid artery dissection (sCAD) may result from arterial inflammation. Periarterial edema (PAE), occasionally described in the vicinity of the mural hematoma in patients with sCAD, may support this hypothesis. Using cervical high-resolution magnetic resonance imaging, three readers, blinded to the mechanism of carotid artery dissection, searched for PAE, defined as periarterial T2-hyperintensity and T1-hypointensity, in 29 consecutive CAD patients categorized as spontaneous CAD (sCAD, n = 18) or traumatic CAD (tCAD, n = 11; i.e., major head or neck trauma within 2 weeks before the clinical onset). The relationships between PAE, inflammatory biological markers, history of infection and CAD mechanism were explored. Multiple CADs (n = 8) were found only in sCAD patients. Compared with tCAD, patients with sCAD were more likely to have a recent history of infection (OR = 12.5 [{sub 95%}CI = 1.3-119], p = 0.03), PAE (83% vs. 27%; OR = 13.3 [{sub 95%}CI = 2.2-82.0], p = 0.005) and to have elevated CRP (OR = 6.1 [{sub 95%}CI = 1.2-32.1], p = 0.0002) or ESR (OR = 8.8 [{sub 95%}CI = 1.5-50.1], p = 0.002) values. Interobserver agreement was 0.84 or higher for PAE identification. sCAD was associated with PAE and biological inflammation. Our results support the hypothesis of an underlying arterial inflammation in sCAD. (orig.)

High-resolution MR imaging of periarterial edema associated with biological inflammation in spontaneous carotid dissection

International Nuclear Information System (INIS)

Naggara, Olivier; Marsico, Rodolpho; Meder, Jean-Francois; Oppenheim, Catherine; Touze, Emmanuel; Mas, Jean-Louis; Leclerc, Xavier; Pruvo, Jean-Pierre; Nguyen, Thanh

2009-01-01

It has been suggested that spontaneous cervical carotid artery dissection (sCAD) may result from arterial inflammation. Periarterial edema (PAE), occasionally described in the vicinity of the mural hematoma in patients with sCAD, may support this hypothesis. Using cervical high-resolution magnetic resonance imaging, three readers, blinded to the mechanism of carotid artery dissection, searched for PAE, defined as periarterial T2-hyperintensity and T1-hypointensity, in 29 consecutive CAD patients categorized as spontaneous CAD (sCAD, n = 18) or traumatic CAD (tCAD, n = 11; i.e., major head or neck trauma within 2 weeks before the clinical onset). The relationships between PAE, inflammatory biological markers, history of infection and CAD mechanism were explored. Multiple CADs (n = 8) were found only in sCAD patients. Compared with tCAD, patients with sCAD were more likely to have a recent history of infection (OR = 12.5 [ 95% CI = 1.3-119], p = 0.03), PAE (83% vs. 27%; OR = 13.3 [ 95% CI = 2.2-82.0], p = 0.005) and to have elevated CRP (OR = 6.1 [ 95% CI = 1.2-32.1], p = 0.0002) or ESR (OR = 8.8 [ 95% CI = 1.5-50.1], p = 0.002) values. Interobserver agreement was 0.84 or higher for PAE identification. sCAD was associated with PAE and biological inflammation. Our results support the hypothesis of an underlying arterial inflammation in sCAD. (orig.)

Toxicity of di-(2-ethylhexyl) phthalate on the anaerobic digestion of wastewater sludge

DEFF Research Database (Denmark)

Alatriste-Mondragon, Felipe; Iranpour, R.; Ahring, Birgitte Kiær

2003-01-01

Previous studies on the microbial degradation of individual phthalic acid esters (PAEs) have demonstrated that the compounds with short ester hydrocarbon chains are easily biodegraded and mineralized, but PAEs with long ester chains are less susceptible to degradation and some of them...... Bureau of Sanitation's Hyperion Treatment Plant. Di (2-ethylhexyl) phthalate (DEHP), the most common persistent PAE found in wastewater, and di-n-butyl phthalate (DBP), a common PAE with short ester chains, were sorbed into the sludge fed to a bench-scale digester for a period of 12 weeks. DEHP...... degradation was always poor, and accumulation of DEHP was correlated with inhibition of the microbial degradation of DBP and with process instability of the test digester. Inhibition of the DBP removal was completely reversed after DEHP addition was discontinued, but biogas production never recovered...

On the variation of environmental radioactivity in Dae-Jeon area (Jan. 1977-Dec. 1981)

International Nuclear Information System (INIS)

Oh, H.P.; Oh, H.J.

1982-01-01

This study concerns with gamma-ray exposure in natural background radiation and radioactivities in the air-borne dust, the fall-out, and the rain-out which had been measured in Dae-Jeon area during the period of five years from Jan. 1, 1977 to Dec. 31, 1981. The special survey results from the 22th, 23th, and 24th nuclear explosion tests carred out by Red China are included in this paper. The results of these measurements are as follows: 1. The average value of natural background radiation in the laboratory 20.69μR/hr, and it is found that the natural background was not affected by the nuclear explosion tests. 2. The average value of radioactivity in the air-borne dust is 0.11pμci/cc, and the maximum value of radioactivity during the period is 0.47pμci/cc. 3. The average value of radioactivity of the fall-out is 0.09mci/km 2 -10d, and the maximum value of radioactivity during the period is 0.84mci/km 2 -10d. 4. The average value of radioactivity in the rain-out is 0.45 x 10 -8 μci/cc, and the maximum value of radioactivity during the period is 1.97 x 10 -8 μci/cc. (Author)

In favor of the revolution: the grotesque and the obsessive destruction as strategies of production - a look into the work of Jan Švankmajer

Directory of Open Access Journals (Sweden)

Caio Cesar Costa e Silva

2014-07-01

Full Text Available The turn of the century led to a new scenario: with all technological developments everything became faster, chaotic and fragmented than before. InEurope, the center of these transformations, the artistic avant-garde, such as Dadaism and Surrealism, tremble all areas of knowledge, the art for art no longer satisfy most their artistic ideals, its subversion was necessary to transform the world. It is in this context that the film becomes focus of expression of these events, their role as a new art becomes increasingly effective. The surrealists saw in the device a channel to release what was conventionally suppressed, allowing that the unconscious could come to the fore as in the dreams, blending the known and the unknown, reality and dream, everyday life and the wonderful. Among these artists are Jan Švankmajer, who also saw in the film a form of expression to his art. This dissertation proposes to explore the strategies used by Švankmajer in the instance of production, through a detailed analysis of two short films - “A quiet week in a house” (TichýTyden v dome, 1969, and “The Death of Stalinism in Bohemia” (Konecstalinismu v Èechách, 1990 - seeking to demonstrate that cinema can chain elements that operate in favor of a goal. Jan Švankmajer keeps a close relationship with the thinking surrealist, the aesthetics of grotesque and obsessive destruction arise here as breakdown elements of reality and it is there that the filmmaker finds material enough to arouse uneasiness in the public.

Mammutraamat viimase viie aasta parimast arhitektuurist / Inga Raukas

Index Scriptorium Estoniae

Raukas, Inga, 1967-

2004-01-01

2004. a. Londonis Phaidon Pressilt ilmunud raamatust "The Phaidon Atlas of Contemporary World Architecture", mis sisaldab 75 riigi 1052 väljapaistvamat ehitist aastaist 1998-2003. Valik tehti Deyan Sudjici juhtimisel, Eestist Veljo Kaasik.. Eestit esindavad Indrek Allmanni paariselamu ja Martin Aunini Orro villa Tabasalus, 3+1 arhitektide Villa-V, Indrek Näki "Neiseri" tehas. Leedut esindab ka 3+1 arhitektide Eesti saatkond

Ühe näoga Janus / Mart Raukas

Index Scriptorium Estoniae

Raukas, Mart

2008-01-01

Tänapäeva lääne poliitikud, lähtudes oma avaldustes aina enam tüüpilistest moraalihinnangutest, unustavad, et ükski moraalne reageering ei ole pelgalt reageering faktidele, vaid selle teeb moraalselt relevantseks olukorrale langetatud hinnang ja sellest lähtuv reageering. Õigluseta ühiskond ei erine suurest röövlijõugust ning see, kes mõistab hukka ühe suurriigi tegevuse, olgu kriitiline ka teise suurjõu osas

Fermentation and nutritive value of silage and hay made from the aerial part of cassava (Manihot esculenta Crantz Padrão de fermentação e valor nutritivo das silagens e do feno da parte aérea de mandioca (Manihot esculenta Crantz

Directory of Open Access Journals (Sweden)

Eduardo Zambello de Pinho

2004-01-01

Full Text Available Cassava (Manihot esculenta Crantz, although native to Brazil, is still underutilized, especially when it comes to using its aerial part. In order to study the potential of the cassava plant for use as animal feed, the present work evaluated the characteristics of the aerial part of cassava when submitted to the processes of ensiling and haymaking. Treatments consisted of: aerial part of the plant ensiled without wilting (PAS; aerial part ensiled after wilting (PAE, and aerial part made into hay (PAF. Chemical analyses were run in order to evaluate the traits that determine the nutritional value of silage and hay. Wilting increased dry matter concentration from 25% to 27.7%, without changing the concentration of soluble carbohydrates (33.3 and 35.5% in the PAS and PAE, respectively, as well as buffer capacity (204 mmol kg-1 DM in PAS and 195 mmol kg-1 DM in PAE. Neither pH (3.57 in fresh silage and 3.60 in PAE nor the ADIN concentration (11.32% of total nitrogen in PAS and 9.99% of total nitrogen in PAE differed between the silages, but ADIN concentration was higher in hay (15.39%. Wilting caused an increase in the concentration of ammonia (from 6.5% of total nitrogen in PAS to 13.0 of total nitrogen in PAE. The levels of volatile fatty acids did not change with wilting. The ensiling process reduced the concentrations of free hydrocyanide (HCN, without, however, affecting cyanohydrin.A mandioca, apesar de ser nativa do Brasil, ainda é sub-utilizada principalmente quando a questão é o aproveitamento da sua parte aérea. Com o objetivo de estudar o potencial da mandioca para alimentação animal, o presente trabalho avaliou as características da parte aérea da planta quando submetida os processos de ensilagem e fenação. Os tratamentos consistiram de: parte aérea ensilada sem emurchecimento (PAS; parte aérea ensilada após 24 horas de emurchecimento (PAE e parte aérea fenada (PAF. As análises químicas foram realizadas a fim de avaliar os

High energy resolution and first time-dependent positron annihilation induced Auger electron spectroscopty

Energy Technology Data Exchange (ETDEWEB)

Mayer, Jakob

2010-04-03

It was the aim of this thesis to improve the existing positron annihilation induced Auger spectrometer at the highly intense positron source NEPOMUC (NEutron induced POsitron source MUniCh) in several ways: Firstly, the measurement time for a single spectrum should be reduced from typically 12 h to roughly 1 h or even less. Secondly, the energy resolution, which amounted to {delta}E/E{approx}10%, should be increased by at least one order of magnitude in order to make high resolution positron annihilation induced Auger spectroscopy (PAES)-measurements of Auger transitions possible and thus deliver more information about the nature of the Auger process. In order to achieve these objectives, the PAES spectrometer was equipped with a new electron energy analyzer. For its ideal operation all other components of the Auger analysis chamber had to be adapted. Particularly the sample manipulation and the positron beam guidance had to be renewed. Simulations with SIMION {sup registered} ensured the optimal positron lens parameters. After the adjustment of the new analyzer and its components, first measurements illustrated the improved performance of the PAES setup: Firstly, the measurement time for short overview measurements was reduced from 3 h to 420 s. The measurement time for more detailed Auger spectra was shortened from 12 h to 80 min. Secondly, even with the reduced measurement time, the signal to noise ratio was also enhanced by one order of magnitude. Finally, the energy resolution was improved to {delta}E/E < 1. The exceptional surface sensitivity and elemental selectivity of PAES was demonstrated in measurements of Pd and Fe, both coated with Cu layers of varying thickness. PAES showed that with 0.96 monolayer of Cu on Fe, more than 55% of the detected Auger electrons stem from Cu. In the case of the Cu coated Pd sample 0.96 monolayer of Cu resulted in a Cu Auger fraction of more than 30% with PAES and less than 5% with electron induced Auger spectroscopy

Did Jan van Eyck build the first photocopier in 1432?

Science.gov (United States)

Stork, David G.

2003-12-01

Recently it has been claimed that some early Renaissance painters used concave mirrors to project real inverted images onto their supports (paper, canvas, oak panel, ...) which they then traced or painted over, and that this was an important source of the increase in realism in European painting around 1420. Key exhibits adduced as evidence in support of this bold theory are a pair of portraits by Jan van Eyck of Cardinal Niccolo Albergati(&?) - a silverpoint study of 1431 and a larger oil of 1432. The contours in these two works bear striking resemblance in form (after being appropriately scaled) and at least one distinctive "relative shift" - evidence that has led proponents of the projection theory to claim that the oil was copied by means of an epidiascope or primitive opaque projector, the shift due to an accidental "bump" during the copying process. We find several difficulties with this optical explanation: there are at least two relative shifts (one horizontal and one vertical), the latter being somewhat unlikely given the putative projection equipment and setup; these shifts are in the ratio of distances of nearly 1:2, a ratio that has no natural role in the projection explanation; any accidental "bump" would surely have been noticed by van Eyck, and if so desired, corrected by him; recent analysis shows physical evidence (tiny pinpricks presumably from mechanical compass) consistent with mechanical transfer that has no role in the optical explanation; and several other points. The fidelity of the copy as well as the direction and relative magnitudes of these shifts are, however, consistent with the use of a familiar grid construction and with mechanical transfer using drawing compass and ruler or Reductionszirkel. Further, there are prominent vertical Bruchkanten (fold or fraction) lines on the grounded paper in the silverpoint study whose orientation and separation have no natural role in an optical theory, but have a plausible role in other explanations

Membaca Simbol pada Lukisan Pertempuran Antara Sultan Agung dan Jan Pieterszoon Coen (1974 Karya S. Sudjojono

Directory of Open Access Journals (Sweden)

Anak Agung Ayu Wulandari

2015-04-01

Full Text Available Sudjojono has produced hundreds of artworks, one of them is the painting of “The Battle between Sultan Agung and Jan Pieterszoon Coen”. Sizing 3 x 10 m, not only this painting is significant in size, it also shows Sudjojono’s in-depth study from aesthetic and historical side. The painting consists of 3 panels depicting Sultan Agung’s meeting with his royals, the battle scene between Mataram and Dutch troops, and the last panel depicting the meeting between JP Coen and Kyai Rangga. Some of the message conveyed by the painter is that the painting was 70% made of historical facts and did not come from the painter imagination only, better to be in peace than war and revenge and the last message is that western and eastern people are actually equal, and as eastern people should not need to have low self-esteem. Besides those messages there are still many symbols and signs that have in-depth meaning which will be studied and examined thoroughly such as figures involved in the battle, location of battle, clothing, etc.  

Dr. Hans Chang, Director, Physics Research Committee, Stichting voor Fundamenteel Onderzoek der Materie (FOM), Dr. Joris Van Enst, Head of Science Policy Division, Ministry of Education, Culture and S cience, Dr. Jan Bezemer, NL Delegate CERN, Netherlands

CERN Multimedia

Patrice Loiez

1999-01-01

Dr. Hans Chang, Director, Physics Research Committee, Stichting voor Fundamenteel Onderzoek der Materie (FOM), Dr. Joris Van Enst, Head of Science Policy Division, Ministry of Education, Culture and S cience, Dr. Jan Bezemer, NL Delegate CERN, Netherlands

Temperature, salinity and other variables collected from discrete sample and profile observations using CTD, bottle and other instruments from the JAN MAYEN in the Norwegian Sea from 1993-04-01 to 1995-11-01 (NODC Accession 0115677)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — NODC Accession 0115677 includes chemical, discrete sample, physical and profile data collected from JAN MAYEN in the Norwegian Sea from 1993-04-01 to 1995-11-01 and...

Aripiprazole treatment of irritability associated with autistic disorder and the relationship between prior antipsychotic exposure, adverse events, and weight change.

Science.gov (United States)

Mankoski, Raymond; Stockton, Gwen; Manos, George; Marler, Sabrina; McQuade, Robert; Forbes, Robert A; Marcus, Ronald

2013-10-01

The purpose of this study was to evaluate the impact of prior antipsychotic exposure (PAE) on safety and tolerability outcomes in pediatric subjects receiving aripiprazole treatment. This study was a post-hoc analysis of pooled data from two 8-week, double-blind, randomized, placebo-controlled studies evaluating aripiprazole for the treatment of irritability in pediatric subjects with autistic disorder, aged 6-17 years. Subjects were stratified by PAE; adverse events (AEs), and changes in weight, and metabolic measures were evaluated. For subjects receiving aripiprazole, regardless of PAE, baseline weight, age, gender, and symptom severity were evaluated in a regression model predicting body weight change. Of 316 randomized subjects, 259 (82.0%) were antipsychotic naïve (AN) and 57 (18.0%) had a PAE. Aripiprazole-treated AN subjects were more likely than PAE subjects to report somnolence (11.9% vs. 2.8%), sedation (22.7% vs. 11.1%), or fatigue (17.0% vs. 13.9%). Rates of extrapyramidal disorder and drooling, but not akathisia or tremor, were marginally higher in AN subjects. Overall, 10.8% of aripiprazole-treated AN subjects had at least one AE leading to discontinuation compared with 8.3% of aripiprazole-treated PAE subjects. AN subjects receiving aripiprazole had a larger change in weight from baseline to endpoint compared with those receiving placebo (1.9 vs. 0.7 kg; treatment difference 1.2 kg, 95% CI: 0.5, 1.9) than PAE subjects receiving aripiprazole compared with subjects receiving placebo (0.4 vs. -0.4 kg; treatment difference 0.9 kg, 95% CI: -0.6, 2.4). Regression analysis identified that younger subjects with higher baseline weight z-score were at highest risk for weight gain. There were no significant changes in metabolic measures compared with placebo in either group. Weight gain was more pronounced in AN subjects and more likely to occur in younger subjects with a higher baseline weight z-score. AN subjects were more likely to experience AEs related

Prenatal Alcohol Exposure Increases Histamine H3 Receptor-Mediated Inhibition of Glutamatergic Neurotransmission in Rat Dentate Gyrus.

Science.gov (United States)

Varaschin, Rafael K; Allen, Nyika A; Rosenberg, Martina J; Valenzuela, C Fernando; Savage, Daniel D

2018-02-01

We have reported that prenatal alcohol exposure (PAE)-induced deficits in dentate gyrus, long-term potentiation (LTP), and memory are ameliorated by the histamine H 3 receptor inverse agonist ABT-239. Curiously, ABT-239 did not enhance LTP or memory in control offspring. Here, we initiated an investigation of how PAE alters histaminergic neurotransmission in the dentate gyrus and other brain regions employing combined radiohistochemical and electrophysiological approaches in vitro to examine histamine H 3 receptor number and function. Long-Evans rat dams voluntarily consumed either a 0% or 5% ethanol solution 4 hours each day throughout gestation. This pattern of drinking, which produces a mean peak maternal serum ethanol concentration of 60.8 ± 5.8 mg/dl, did not affect maternal weight gain, litter size, or offspring birthweight. Radiohistochemical studies in adult offspring revealed that specific [ 3 H]-A349821 binding to histamine H 3 receptors was not different in PAE rats compared to controls. However, H 3 receptor-mediated G i /G o protein-effector coupling, as measured by methimepip-stimulated [ 35 S]-GTPγS binding, was significantly increased in cerebral cortex, cerebellum, and dentate gyrus of PAE rats compared to control. A LIGAND analysis of detailed methimepip concentration-response curves in dentate gyrus indicated that PAE significantly elevates receptor-effector coupling by a lower affinity H 3 receptor population without significantly altering the affinities of H 3 receptor subpopulations. In agreement with the [ 35 S]-GTPγS studies, a similar range of methimepip concentrations also inhibited electrically evoked field excitatory postsynaptic potential responses and increased paired-pulse ratio, a measure of decreased glutamate release, to a significantly greater extent in dentate gyrus slices from PAE rats than in controls. These results suggest that a PAE-induced elevation in H 3 receptor-mediated inhibition of glutamate release from

Fine motor skills in a population of children in remote Australia with high levels of prenatal alcohol exposure and Fetal Alcohol Spectrum Disorder.

Science.gov (United States)

Doney, Robyn; Lucas, Barbara R; Watkins, Rochelle E; Tsang, Tracey W; Sauer, Kay; Howat, Peter; Latimer, Jane; Fitzpatrick, James P; Oscar, June; Carter, Maureen; Elliott, Elizabeth J

2017-11-21

Many children in the remote Fitzroy Valley region of Western Australia have prenatal alcohol exposure (PAE). Individuals with PAE can have neurodevelopmental impairments and be diagnosed with one of several types of Fetal Alcohol Spectrum Disorder (FASD). Fine motor skills can be impaired by PAE, but no studies have developed a comprehensive profile of fine motor skills in a population-based cohort of children with FASD. We aimed to develop a comprehensive profile of fine motor skills in a cohort of Western Australian children; determine whether these differed in children with PAE or FASD; and establish the prevalence of impairment. Children (n = 108, 7 to 9 years) were participants in a population-prevalence study of FASD in Western Australia. Fine motor skills were assessed using the Bruininks-Oseretsky Test of Motor Proficiency, which provided a Fine Motor Composite score, and evaluated Fine Manual Control (Fine Motor Precision; Fine Motor Integration) and Manual Coordination (Manual Dexterity; Upper-Limb Coordination). Descriptive statistics were reported for the overall cohort; and comparisons made between children with and without PAE and/or FASD. The prevalence of severe (≤ 2nd percentile) and moderate (≤16th percentile) impairments was determined. Overall, Fine Motor Composite scores were 'average' (M = 48.6 ± 7.4), as were Manual Coordination (M = 55.7 ± 7.9) and Fine Manual Control scores (M = 42.5 ± 6.2). Children with FASD had significantly lower Fine Motor Composite (M = 45.2 ± 7.7 p = 0.046) and Manual Coordination scores (M = 51.8 ± 7.3, p = 0.027) than children without PAE (Fine Motor Composite M = 49.8 ± 7.2; Manual Coordination M = 57.0 ± 7.7). Few children had severe impairment, but rates of moderate impairment were very high. Different types of fine motor skills should be evaluated in children with PAE or FASD. The high prevalence of fine motor impairment in our

The role of prostatic arterial embolization in patients with benign prostatic hyperplasia: a systematic review

NARCIS (Netherlands)

Schreuder, S. M.; Scholtens, A. E.; Reekers, J. A.; Bipat, S.

2014-01-01

This study was designed to summarize the evidence on clinical outcomes and complications of prostatic arterial embolization (PAE) in patients with benign prostatic hyperplasia (BPH). We searched Medline and Embase for PAE trials of patients with BPH upto November 2013. Two reviewers independently

Evaluation of pH-sensitive poly(β-amino ester)-graft-poly(ethylene glycol) and its usefulness as a pH-sensor and protein carrier.

Science.gov (United States)

Kim, Min Sang; Gao, Guang Hui; Kang, Seong Woo; Lee, Doo Sung

2011-07-07

In this study, some possible biomedical applications of a pH-sensitive and amphiphilic copolymer as a pH sensor and protein delivery system are reported. PAE-g-PEG was used as a pH-sensitive polymer that can exhibit a sharp pH-dependent transition. Various fluorescent dyes including pyrene and RITC can be used to label the pH-sensitive polymer PAE-g-PEG, which was evaluated for protein encapsulation. pH-sensing was possible by observing excimer formation of the labeled pyrene via pH-dependent expansion of the polymeric chain. Also, it was confirmed that FITC-BSA could be entrapped in RITC-labeled pH-sensitive micelles of PAE-g-PEG by FRET. As a result, PAE-g-PEG can be a pH sensor and carrier for protein delivery. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Characterization of Polyethylene-Graft-Sulfonated Polyarylsulfone Proton Exchange Membranes for Direct Methanol Fuel Cell Applications

Directory of Open Access Journals (Sweden)

Hyung Kyu Kim

2015-12-01

Full Text Available This paper examines polymer film morphology and several important properties of polyethylene-graft-sulfonated polyarylene ether sulfone (PE-g-s-PAES proton exchange membranes (PEMs for direct methanol fuel cell applications. Due to the extreme surface energy differences between a semi-crystalline and hydrophobic PE backbone and several amorphous and hydrophilic s-PAES side chains, the PE-g-s-PAES membrane self-assembles into a unique morphology, with many proton conductive s-PAES channels embedded in the stable and tough PE matrix and a thin hydrophobic PE layer spontaneously formed on the membrane surfaces. In the bulk, these membranes show good mechanical properties (tensile strength >30 MPa, Young’s modulus >1400 MPa and low water swelling (λ < 15 even with high IEC >3 mmol/g in the s-PAES domains. On the surface, the thin hydrophobic and semi-crystalline PE layer shows some unusual barrier (protective properties. In addition to exhibiting higher through-plane conductivity (up to 160 mS/cm than in-plane conductivity, the PE surface layer minimizes methanol cross-over from anode to cathode with reduced fuel loss, and stops the HO• and HO2• radicals, originally formed at the anode, entering into PEM matrix. Evidently, the thin PE surface layer provides a highly desirable protecting layer for PEMs to reduce fuel loss and increase chemical stability. Overall, the newly developed PE-g-s-PAES membranes offer a desirable set of PEM properties, including conductivity, selectivity, mechanical strength, stability, and cost-effectiveness for direct methanol fuel cell applications.

The tissue distribution and excretion study of paeoniflorin-6'-O-benzene sulfonate (CP-25) in rats.

Science.gov (United States)

Zhao, Mingyi; Zhou, Peng; Yu, Jun; James, Asenso; Xiao, Feng; Wang, Chun; Wei, Wei

2018-03-09

Paeoniflorin-6'-O-benzene sulfonate (code: CP-25) is a novel ester derivative of paeoniflorin (Pae). Compared to Pae, CP-25 has higher lipid solubility, bioavailability and better bioactivity. However, the tissue distribution and excretion of CP-25 still remain unknown. The LC-MS method was applied to investigate the tissue distribution and excretion of CP-25 in rats. As such, 50 mg/kg of CP-25 and Pae were administered to rats in multiple doses via an oral route. CP-25 and Pae were distributed widely and rapidly in all the tested tissues. Compared with Pae, the concentrations of CP-25 were almost increased evidently in most tissues. The highest CP-25 level was found in the liver (1476.33 ± 535.20 ng/g, male; 1970.38 ± 177.21 ng/g, female) at 3 h, and a high concentration of CP-25 was detected in male and female intestine, synovium, muscle, lung, and brain. Following a single oral dose of 50 mg/kg of CP-25 in rats, the total excretion of CP-25 was merely 21.8% (18.40, 3.19 and 0.22% for feces, bile and urine, respectively) in males; and was approximately 21.3% (14.04, 7.16 and 0.14% for feces, bile and urine, respectively) in females. The results indicated that the CP-25 concentration was higher in major tissues than Pae; CP-25 was primarily excreted through the feces; and there were gender-related differences in the tissue distribution and excretion.

Apresentação do n.11 v. 21 jan./jun. 2017

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Fábio Luiz de Arruda Herrig

2017-07-01

Full Text Available A Revista Eletrônica História em Reflexão, neste ano de 2017, tem a dupla satisfação de oferecer mais uma edição aos seus leitores e comemorar dez anos de sua criação, no ano de 2007. Em nome da REHR, dirigida pelos alunos do Programa de Pós-Graduação em História, da Universidade Federal da Grande Dourados, gostaríamos de agradecer, por essa década de intenso trabalho, a todos e todas que colaboram: aos alunos do PPGH, que com o auxílio dos professores criaram e tocaram esse projeto adiante; aos autores que colaboraram com sua produção; aos pareceristas (integrantes do conselho consultivo, mas aos ad hoc também que de maneira séria e eficiente colaboram para o crescimento da qualidade da REHR; ao técnicos que assistiram-nos em face dos problemas; e, em absoluto, ao leitores. Cheios de orgulho, portanto, apresentamos a Edição n° 11, v. 21 jan/jun 2017, que conta, em sua primeira sessão com um dossiê organizado pela Professora Dra. Luciana Lilian de Miranda, do Programa de Pós-Graduação da UFG e do Professor Dr. Julierme Morais, da UEG, a quem deixamos a cargo a apresentação do respectivo Dossiê, intitulado Intelectuais, Cultura e Modernismo, que se encaixa na esteira das frutíferas discussões que tratam da História Intelectual e das relações entre História, Literatura e Cinema, campos caros à Historia contemporânea.

Oceanographic profile; phosphate, silicate and other measurements collected using bottle and high resolution CTD from the DANA, JAN MAYEN (LAHV) and other platforms in the Coastal N Atlantic, Arctic and other locations from 1995 to 1997 (NODC Accession 0000566)

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National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profile, zooplankton, and nutrients data were collected using net and bottle casts from DANA and JAN MAYEN in the North Atlantic Ocean. Data were...

Hats off to CERN's Master of Apprenticeships!

CERN Multimedia

2004-01-01

Roland Gay of the HR Department (at right) recently received a special diploma from the Geneva Industrial Union (UIG). Presented by Carlo Lamprecht, Head of the Department of Economy, Employment and External Affairs of the State of Geneva, the diploma was awarded in recognition of the 199 CERN apprentices Roland has guided through the Certificat Fédéral de Capacité (CFC), an end-of-apprenticeship certificate awarded by the Cantonal authorities. Roland will be retiring in December 2004 after 37 years of service, 32 of which he spent in the role of apprenticeship supervisor.

Phthalate esters contamination in soils and vegetables of plastic film greenhouses of suburb Nanjing, China and the potential human health risk.

Science.gov (United States)

Ma, Ting Ting; Wu, Long Hua; Chen, Like; Zhang, Hai Bo; Teng, Ying; Luo, Yong Ming

2015-08-01

The contamination of phthalate esters (PAEs) has become a potential threat to the environment and human health because they could be easily released as plasticizers from the daily supply products, especially in polyethylene films. Concentration levels of total six PAEs, nominated as priority pollutants by the US Environmental Protection Agency (USEPA), were investigated in soils and vegetables from four greenhouse areas in suburbs of Nanjing, East China. Total PAEs concentration ranged from 930 ± 840 to 2,450 ± 710 μg kg(-1) (dry weight (DW)) in soil and from 790 ± 630 to 3,010 ± 2,130 μg kg(-1) in vegetables. Higher concentrations of PAEs were found in soils except in Suo Shi (SS) area and in vegetables, especially in potherb mustard and purple tsai-tai samples. Risk assessment mainly based on the exposures of soil ingestion and daily vegetable intake indicated that bis(2-ethylhexyl) phthalate (DEHP) in the samples from Gu Li (GL) and Hu Shu (HS) exhibited the highest hazard to children less than 6-year old. Therefore, the human health risk of the PAEs contamination in soils and vegetables should greatly be of a concern, especially for their environmental estrogen analog effects.

Evaluating the controls on Tourmaline Crystallization in the mylonitic granite-gneiss pluton in the Northeastern of Jan mine (Lorestan province

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Arezoo Moradi

2017-02-01

Full Text Available Introduction The study area is a part of the Sanandaj- Sirjan zone that is located in the NW of Azna city and NE of the dimension stone mine of Jan between 49° 11' 41"and 49° 16' 07" E longitude and 33° 36'35" and 33° 38'12" N latitude., A pluton of mylonitic granite-gneiss is exposed in the area which contains abundant tourmalines as black and patchy or subgrain association. Geochemically, the studied granite-gneiss is A-type, peraluminous to slightly metaluminous and calc – alkaline to slightly alkaline (Moradi et al., 7. The electron microprobe analyses of the tourmalines display shorl-dravite in composition with more tendency to shorl (Moradi et al., 2015. In this paper we try to study the petrological sites of tourmaline formation with associated minerals, controller factors of crystallization using mineral chemistry of tourmaline, comprehensive behavior of trace elements in the tourmaline, synthetic phase diagrams and finally relationships between the associated minerals. Materials and methods The results of trace-element and major-element analyses were obtained from one polished thin section including 2 tourmaline grains. Major-element analyses of tourmaline were obtained at Oklahama City University of America using the JEOL 8200 electron microprobe with a spot size of 5 μm and trace-element analyses were performed on just a sample by Laser Ablation-Inductively Coupled Plasma-Mass Spectroscopy (LA-ICP-MS a 193nm ArF excimer laser ablation system (MicroLas GeoLas 200Q in combination with a quadrupole ICP-MS (Micromass Platform ICP at Utrecht University of Netherland. Representative EMP and LA-ICP-MS analyses of tourmaline samples are presented in Tables1 and 2. Results The results of LA-ICP-MS on tourmalines of Jan mine in the North east of mylonitic granite-gneiss body show that distribution and diffusion of trace elements during the growth of tourmaline trend is positive on the plots of binary Mn versus Fetot / (Fetot +Mg and it

Soldiers for the virtual battlefield : Even at secondary school, Jan Paul van Waveren spent more time on computer games than on his homework, though he doesn't seem to have suffered from it

NARCIS (Netherlands)

Van Waveren, J.P.; Rothkrantz, L.; Jongeneel, C.

2001-01-01

Even at secondary school, Jan Paul van Waveren spent more time on computer games than on his homework,though he doesnt seem to have suffered from it. At university he spent some of his time linking up personal computers with his friends, trying to blast each other to virtual smithereens in a game of

Stemcell Information: SKIP000355 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available rius Aquarius ... 20-29 Female ... -- No PL-iPS-11|PAE551-derived iPS cells PAE551由来iPS細胞 human ES-li...amics in human induced pluripotent stem cells over time. Nishino K, Toyoda M, Yamazaki-Inoue M, Fukawatase Y

The role of the family in a lonely life and works of the modern writer – Jan Rybowicz [Rola rodziny w samotnym życiu i twórczości współczesnego pisarza – Jana Rybowicza

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Paulina LITWICKA

2017-11-01

Full Text Available The biographical and historical-literary analysis of works of the modern writer Jan Rybowicz indicates that having a family of one’s own was an unreachable dream for the artist, which affected his self-esteem and was a chance for his complete fulfillment. Letters to Elisabeth are showing problems of a sensitive artist in his contacts with women. The selected literary works draw attention at the issues of a lonely man missing a wife and children which he has never had. Autobiographical prose points to the passing time and difficult reality that made having a family impossible for the writer. Jan Rybowicz’s works show a man torn between his wishes and reality. A desire of having his own family gave him the strength to write, but, on the other hand, it made him suffer.

Fixed versus variable practice for teaching medical students the management of pediatric asthma exacerbations using simulation.

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Drummond, David; Truchot, Jennifer; Fabbro, Eleonora; Ceccaldi, Pierre-François; Plaisance, Patrick; Tesnière, Antoine; Hadchouel, Alice

2018-02-01

Simulation-based trainings represent an interesting approach to teach medical students the management of pediatric asthma exacerbations (PAEs). In this study, we compared two pedagogical approaches, training students once on three different scenarios of PAEs versus training students three times on the same scenario of PAE. Eighty-five third-year medical students, novice learners for the management of PAEs, were randomized and trained. Students were assessed twice, 1 week and 4 months after the training, on a scenario of PAE new to both groups and on scenarios used during the training. The main outcome was the performance score on the new scenario of PAE at 1 week, assessed on a checklist custom-designed for the study. All students progressed rapidly and acquired excellent skills. One week after the training, there was no difference between the two groups on all the scenarios tested, including the new scenario of PAE (median performance score (IQR) of 8.3 (7.4-10.0) in the variation group versus 8.0 (6.0-10.0) in the repetition group (p = 0.16)). Four months later, the performance of the two groups remained similar. Varying practice with different scenarios was equivalent to repetitive practice on the same scenario for novice learners, with both methods leading to transfer and long-term retention of the skills acquired during the training. What is known: • Simulation-based trainings represent an interesting approach to teach medical students the management of pediatric asthma exacerbations. • It is unclear whether students would benefit more from repetitive practice on the same scenario of asthma exacerbation or from practice on different scenarios in terms of transfer of skills. What is new: • An individual 30-min training on the management of pediatric asthma exacerbations using simulation allows transfer and long-term retention of the skills acquired. • Varying practice with different scenarios is equivalent to repetitive practice on the same

Analysis of phthalate esters in soils near an electronics manufacturing facility and from a non-industrialized area by gas purge microsyringe extraction and gas chromatography

Energy Technology Data Exchange (ETDEWEB)

Wu, Wei [MOE Key Laboratory of Environment and Health, Institute of Environmental Medicine, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei (China); Hu, Jia [Suzhou Center for Disease Prevention and Control, Suzhou, Jiangsu (China); Wang, Jinqi; Chen, Xuerong; Yao, Na [MOE Key Laboratory of Environment and Health, Institute of Environmental Medicine, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei (China); Tao, Jing, E-mail: jingtao1982@126.com [MOE Key Laboratory of Environment and Health, Institute of Environmental Medicine, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei (China); Zhou, Yi-Kai, E-mail: zhouyk@mails.tjmu.edu.cn [MOE Key Laboratory of Environment and Health, Institute of Environmental Medicine, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei (China)

2015-03-01

Here, a novel technique is described for the extraction and quantitative determination of six phthalate esters (PAEs) from soils by gas purge microsyringe extraction and gas chromatography. Recovery of PAEs ranged from 81.4% to 120.3%, and the relative standard deviation (n = 6) ranged from 5.3% to 10.5%. Soil samples were collected from roadsides, farmlands, residential areas, and non-cultivated areas in a non-industrialized region, and from the same land-use types within 1 km of an electronics manufacturing facility (n = 142). Total PAEs varied from 2.21 to 157.62 mg kg{sup −1} in non-industrialized areas and from 8.63 to 171.64 mg kg{sup −1} in the electronics manufacturing area. PAE concentrations in the non-industrialized area were highest in farmland, followed (in decreasing order) by roadsides, residential areas, and non-cultivated soil. In the electronics manufacturing area, PAE concentrations were highest in roadside soils, followed by residential areas, farmland, and non-cultivated soils. Concentrations of dimethyl phthalate (DMP), diethyl phthalate (DEP), and di-n-butyl phthalate (DnBP) differed significantly (P < 0.01) between the industrial and non-industrialized areas. Principal component analysis indicated that the strongest explanatory factor was related to DMP and DnBP in non-industrialized soils and to butyl benzyl phthalate (BBP) and DMP in soils near the electronics manufacturing facility. Congener-specific analysis confirmed that diethylhexyl phthalate (DEHP) was a predictive indication both in the non-industrialized area (r{sup 2} = 0.944, P < 0.01) and the industrialized area (r{sup 2} = 0.860, P < 0.01). The higher PAE contents in soils near the electronics manufacturing facility are of concern, considering the large quantities of electronic wastes generated with ongoing industrialization. - Highlights: • A new method for determining phthalate esters in soil samples was developed. • Investigate six phthalates near an industry and a

Secondary Agricultural Education Teachers as Agents of Change in Oklahoma and the Adoption of Precision Agriculture

Science.gov (United States)

Nickeson, Beth

2013-01-01

Research indicates that precision agricultural education (PAE) in Oklahoma affects environmental quality, water conservation, and crop yields. The purpose of this mixed methods study was to explore the nature and perceived effectiveness of PAE in Oklahoma secondary agricultural education classes. The study was framed by the diffusion of…

Jan Rak and Michael J. Tannenbaum present the book "High-pT physics in the heavy ion era"

CERN Multimedia

2013-01-01

Thursday 13 June 2013 from 4 p.m. to 5 p.m. in the Library, Bldg. 52 1-052 The book provides an overview of the basic concepts of large transverse momentum particle physics, with a focus on pQCD phenomena. It examines high-pT probes of relativistic heavy-ion collisions and will serve as a handbook for those working on RHIC and LHC data analyses. Starting with an introduction and review of the field, the authors look at basic observables and experimental techniques, concentrating on relativistic particle kinematics, before moving onto a discussion about the origins of high-pT physics. The main features of high-pT physics are placed within a historical context and the authors adopt an experimental outlook, highlighting the most important discoveries leading up to the foundation of modern QCD theory. High-pT physics in the heavy ion era, by Jan Rak and Michael J. Tannenbaum,  Cambridge University Press, 2013, ISBN  9780521190299. *Coffee will be served from 3 p.m.*

Endoplasmic reticulum stress-induced resistance to doxorubicin is reversed by paeonol treatment in human hepatocellular carcinoma cells.

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Lulu Fan

Full Text Available BACKGROUND: Endoplasmic reticulum stress (ER stress is generally activated in solid tumors and results in tumor cell anti-apoptosis and drug resistance. Paeonol (Pae, 2-hydroxy-4-methoxyacetophenone, is a natural product extracted from the root of Paeonia Suffruticosa Andrew. Although Pae displays anti-neoplastic activity and increases the efficacy of chemotherapeutic drugs in various cell lines and in animal models, studies related to the effect of Pae on ER stress-induced resistance to chemotherapeutic agents in hepatocellular carcinoma (HCC are poorly understood. METHODOLOGY/PRINCIPAL FINDINGS: In this study, we investigated the effect of the endoplasmic reticulum (ER stress response during resistance of human hepatocellular carcinoma cells to doxorubicin. Treatment with the ER stress-inducer tunicamycin (TM before the addition of doxorubicin reduced the rate of apoptosis induced by doxorubicin. Interestingly, co-pretreatment with tunicamycin and Pae significantly increased apoptosis induced by doxorubicin. Furthermore, induction of ER stress resulted in increasing expression of COX-2 concomitant with inactivation of Akt and up-regulation of the pro-apoptotic transcription factor CHOP (GADD153 in HepG2 cells. These cellular changes in gene expression and Akt activation may be an important resistance mechanism against doxorubicin in hepatocellular carcinoma cells undergoing ER stress. However, co-pretreatment with tunicamycin and Pae decreased the expression of COX-2 and levels of activation of Akt as well as increasing the levels of CHOP in HCC cells. CONCLUSIONS/SIGNIFICANCE: Our results demonstrate that Pae reverses ER stress-induced resistance to doxorubicin in human hepatocellular carcinoma cells by targeting COX-2 mediated inactivation of PI3K/AKT/CHOP.

Clinical, Laboratorial, and Urodynamic Findings of Prostatic Artery Embolization for the Treatment of Urinary Retention Related to Benign Prostatic Hyperplasia. A Prospective Single-Center Pilot Study

International Nuclear Information System (INIS)

Antunes, Alberto A.; Carnevale, Francisco C.; Motta Leal Filho, Joaquim M. da; Yoshinaga, Eduardo M.; Cerri, Luciana M. O.; Baroni, Ronaldo H.; Marcelino, Antonio S. Z.; Cerri, Giovanni G.; Srougi, Miguel

2013-01-01

PurposeThis study was designed to describe the clinical, laboratorial, and urodynamic findings of prostatic artery embolization (PAE) in patients with urinary retention due to benign prostatic hyperplasia (BPH).MethodsA prospective study of 11 patients with urinary retention due to BPH was conducted. Patients underwent physical examination, prostate specific antigen (PSA) measurement, transrectal ultrasound, and magnetic resonance imaging. International prostate symptom score (IPSS), quality of life (QoL), and urodynamic testing were used to assess the outcome before and after 1 year.ResultsClinical success was 91 % (10/11 patients) with a mean follow-up of 22.3 months (range, 12–41 months). At the first year follow-up, the mean IPSS score was 2.8 points (p = 0.04), mean QoL was 0.4 points (p = 0.001), mean PSA decreased from 10.1 to 4.3 ng/mL (p = 0.003), maximum urinary flow (Qmax) improved from 4.2 to 10.8 mL/sec (p = 0.009), and detrusor pressure (Pdet) decreased from 85.7 to 51.5 cm H 2 O (p = 0.007). Before PAE, Bladder Outlet Obstruction Index (BOOI) showed values >40 in 100 % of patients. After PAE, 30 % of patients were >40 (obstructed), 40 % were between 20 and 40 (undetermined), and 30 % were <20 (unobstructed). Patients with a BOOI <20 had higher PSA values at 1-day after PAE.ConclusionsClinical and urodynamic parameters improved significantly after PAE in patients with acute urinary retention due to BPH. Total PSA at day 1 after PAE was higher in patients with unobstructed values in pressure flow studies

Clinical, Laboratorial, and Urodynamic Findings of Prostatic Artery Embolization for the Treatment of Urinary Retention Related to Benign Prostatic Hyperplasia. A Prospective Single-Center Pilot Study

Energy Technology Data Exchange (ETDEWEB)

Antunes, Alberto A. [University of Sao Paulo Medical School, Division of Urology (Brazil); Carnevale, Francisco C., E-mail: fcarnevale@uol.com.br; Motta Leal Filho, Joaquim M. da [University of Sao Paulo Medical School, Interventional Radiology Unit (Brazil); Yoshinaga, Eduardo M. [University of Sao Paulo Medical School, Division of Urology (Brazil); Cerri, Luciana M. O. [University of Sao Paulo Medical School, Ultrasound Unit (Brazil); Baroni, Ronaldo H. [University of Sao Paulo Medical School, Magnetic Resonance Unit (Brazil); Marcelino, Antonio S. Z. [University of Sao Paulo Medical School, Ultrasound Unit (Brazil); Cerri, Giovanni G. [University of Sao Paulo Medical School, Radiology Department (Brazil); Srougi, Miguel [University of Sao Paulo Medical School, Division of Urology (Brazil)

2013-08-01

PurposeThis study was designed to describe the clinical, laboratorial, and urodynamic findings of prostatic artery embolization (PAE) in patients with urinary retention due to benign prostatic hyperplasia (BPH).MethodsA prospective study of 11 patients with urinary retention due to BPH was conducted. Patients underwent physical examination, prostate specific antigen (PSA) measurement, transrectal ultrasound, and magnetic resonance imaging. International prostate symptom score (IPSS), quality of life (QoL), and urodynamic testing were used to assess the outcome before and after 1 year.ResultsClinical success was 91 % (10/11 patients) with a mean follow-up of 22.3 months (range, 12-41 months). At the first year follow-up, the mean IPSS score was 2.8 points (p = 0.04), mean QoL was 0.4 points (p = 0.001), mean PSA decreased from 10.1 to 4.3 ng/mL (p = 0.003), maximum urinary flow (Qmax) improved from 4.2 to 10.8 mL/sec (p = 0.009), and detrusor pressure (Pdet) decreased from 85.7 to 51.5 cm H{sub 2}O (p = 0.007). Before PAE, Bladder Outlet Obstruction Index (BOOI) showed values >40 in 100 % of patients. After PAE, 30 % of patients were >40 (obstructed), 40 % were between 20 and 40 (undetermined), and 30 % were <20 (unobstructed). Patients with a BOOI <20 had higher PSA values at 1-day after PAE.ConclusionsClinical and urodynamic parameters improved significantly after PAE in patients with acute urinary retention due to BPH. Total PSA at day 1 after PAE was higher in patients with unobstructed values in pressure flow studies.

Clinical evaluation of embolization of the superior vesical prostatic artery for treatment of benign prostatic hyperplasia: a single-center retrospective study.

Science.gov (United States)

Qiu, Zhilei; Zhang, Changcun; Wang, Xinsheng; Cheng, Kai; Liang, Xin; Wang, Dawen; Hou, Sichuan; Wang, Xinsheng

2017-12-01

Non-surgical minimally invasive treatments are greatly needed for patients with symptomatic benign prostatic hyperplasia (BPH), for whom medical treatment has failed and surgery is contraindicated. This study retrospectively evaluated the efficacy and safety of super-selective prostatic artery embolization (PAE) for BPH, relative to transurethral resection of the prostate (TURP). To clinically evaluate the efficacy and safety of super-selective PAE for BPH, relative to TURP. From February 2012 to March 2015, patients with BPH underwent selective PAE (n = 17) or TURP (control group; n = 40). Prostate volume, maximum urinary flow rate (Qmax), International Prostate Symptoms Score (IPSS), and quality of life (QoL) score were evaluated at baseline and postoperative 3, 6, and 12 months. Complications were also recorded. All the procedures were technically successfully. At postoperative 1 year, patients given PAE had significantly greater prostate volume (64.6 ±10.2 ml), IPSS (23.9 ±4.9), and QoL (4.1 ±0.7) compared with the control patients (42.0 ±7.5 ml, 13.1 ±3.5, and 2.1 ±0.7, respectively). The Qmax of the PAE group (9.5 ±3.7 ml/s) was significantly lower than that of the control (21.8 ±4.2 ml/s). The changes in parameters of the TURP patients relative to the preoperative baseline were significantly greater than those of the PAE group. No severe complications occurred. Prostatic artery embolization was demonstrated as safe and effective and may be considered an alternative treatment for BPH patients, especially for those who are not candidates for or refuse surgery.

[JAN JĘDRZEJEWICZ AND EUROPEAN ASTRONOMY OF THE 2ND HALF OF THE 19TH CENTURY].

Science.gov (United States)

Siuda-Bochenek, Magda

2015-01-01

Jan Jędrzejewicz was an amateur astronomer who in the 2nd half of the 19th century created an observation centre, which considering the level of research was comparable to the European ones. Jędrzejewicz settled down in Plonsk in 1862 and worked as a doctor ever since but his greatest passion was astronomy, to which he dedicated all his free time. In 1875 Jędrzejewicz finished the construction of his observatory. He equipped it with basic astronomical and meteorological instruments, then began his observations and with time he became quite skilled in it. Jędrzejewicz focused mainly on binary stars but he also pointed his telescopes at the planets of the solar system, the comets, the Sun, as well as all the phenomena appearing in the sky at that time. Thanks to the variety of the objects observed and the number of observations he stood out from other observers in Poland and took a very good position in the mainstream of the 19th-century astronomy in Europe. Micrometer observations of binary stars made in Płońsk gained recognition in the West and were included in the catalogues of binary stars. Interest in Jędrzejewicz and his observatory was confirmed by numerous references in the English "Nature" magazine.

Letter of Polish Hetman Jan Zamoyski “About Passage of Tatars through Pokuttya in 1594”.

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Roman Hautala

2017-06-01

Full Text Available The present article contains the text of the letter sent by Polish hetman Jan Zamoyski to Cardinal Cinzio Aldobrandini August 12, 1594 describing the circumstances of the recent invasion of Tatar troops in Hungary. Judging by contents of the letter, Zamoyski did not hide his desire to be justified in the eyes of the Roman Curia for the ineffectiveness of his actions, which would have to prevent Tatars to invade Hungary through Ukrainian territory that was subordinated to Rzeczpospolita. Thus, this letter is interesting for two reasons. In the first place, Zamoyski’s letter contains detailed information about movement of Tartar troops to the west and stratagemme of khan Ghazi Giray, which allowed Tatars to lull Polish hetman and painlessly penetrate into Hungarian territory. On the other hand, the letter contains somewhat clumsy attempts of Zamoyski to justify his unsuccessful actions, which represent a particular interest. This article, therefore, contains the Latin text of the letter and its Russian translation as well as the preface and necessary comments to the text explaining the reasons and the very course of Tatar invasion of the Kingdom of Hungary. In addition, the authors placed facsimiles of two handwritten copies of the letter from the Biblioteca Ambrosiana in Milan at the end of the article.

Mod en neutral seksualitet!

DEFF Research Database (Denmark)

Leer, Jonatan

2013-01-01

Towards a Neutral Sexuality! or Roland Barthes as a Queer Thinker? This article argues that the work of Roland Barthes has interesting perspectives in common with the queer theory. This argument will be put forward by using his concept of ‘the neutral’ that Barthes defines as “that which outplays...

Moderate Maternal Alcohol Exposure on Gestational Day 12 Impacts Anxiety-Like Behavior in Offspring

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Siara K. Rouzer

2017-09-01

Full Text Available Among the numerous consequences of prenatal alcohol exposure (PAE is an increase in anxiety-like behavior that can prove debilitating to daily functioning. A significant body of literature has linked gestational day 12 (G12 heavy ethanol exposure with social anxiety, evident in adolescent males and females. However, the association between non-social anxiety-like behavior and moderate alcohol exposure, a more common pattern of drinking in pregnant women, is yet unidentified. To model moderate PAE (mPAE, we exposed pregnant Sprague-Dawley rats to either room air or vaporized ethanol for 6 h on G12. Adolescent offspring were then tested on postnatal days (P 41–47 in one of the following four anxiety assays: novelty-induced hypophagia (NIH, elevated plus maze (EPM, light-dark box (LDB and open-field (OF. Our findings revealed significant increases in measures of anxiety-like behavior in male PAE offspring in the NIH, LDB and OF, with no differences observed in females on any test. Additionally, male offspring who demonstrated heightened anxiety-like behavior as adolescents demonstrated decreased anxiety-like behavior in adulthood, as measured by a marble-burying test (MBT, while females continued to be unaffected in adulthood. These results suggest that mPAE leads to dynamic changes in anxiety-like behavior exclusively in male offspring.

Applying a Developmental Framework to the Self-Regulatory Difficulties of Young Children with Prenatal Alcohol Exposure: A Review.

Science.gov (United States)

Reid, Natasha; Petrenko, Christie L M

2018-06-01

Prenatal alcohol exposure (PAE) can be associated with significant difficulties in self-regulatory abilities. As such, interventions have been developed that focus on improving varying aspects of self-regulation for this population. The application of a multilevel theoretical framework that describes the development of self-regulation during early childhood could further advance the field. First, this framework could assist in elucidating mechanisms in the trajectories of early adjustment problems in this population and, second, informing the development of more precise assessment and interventions for those affected by PAE. The aims of the current review were to provide an overview of the self-regulatory framework proposed by Calkins and colleagues (e.g., Calkins, 2007; Calkins and Fox, 2002); examine the self-regulatory difficulties that are commonly experienced during infancy (i.e., 0 to 2 years) and early childhood (i.e., 3 to 8 years) in children with PAE in the context of the developmental framework; and describe how the framework can inform the development of future assessment and intervention provision for young children with PAE. The application of a developmental framework, such as proposed by Calkins and colleagues, allows for a systematic and theoretically driven approach to assessment and intervention programs for young children with PAE. Copyright © 2018 by the Research Society on Alcoholism.

3D Density Structure of Oceanic Lithosphere Affected by A Plume: A Case Study from the Greater Jan Mayen-East Greenland Region (NE Atlantic)

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Tan, P.; Sippel, J.; Breivik, A. J.; Scheck-Wenderoth, M.; Meeßen, C.

2017-12-01

Unraveling the density structure of the oceanic lithosphere north of Iceland is key for understanding the effects of the Iceland Plume on the mid-ocean ridges of the greater Jan Mayen-East Greenland Region. We use a data-integrative approach for 3D gravity modeling to develop new insights into the crust and upper mantle density structure of this region. First, we obtain the 3D density structure of the sediments and crust from interpretations of regional reflection and refraction seismic lines. Then, the temperature and density structure of the mantle between 50 and 250 km are derived from a published shear-wave velocity (Vs) tomography model. To assess the density configuration between the Moho and 50 km depth, we follow a combined forward and inverse 3D gravity modeling approach. The Vs tomography and derived density of the deeper mantle (>50 km depth) reveal that the low-density anomaly related to the Iceland plume gets weaker with increasing distance from the plume, i.e. from the strongly influenced Middle Kolbeinsey Ridge (MKR) to the Mohn's Ridge. The West Jan Mayen Fracture Zone is identified as a main mantle density contrast, indicative of differences in the thermal evolution of the ridge systems it separates. Beneath the MKR region, the low-density anomaly at depths of >50 km continues upwards into the uppermost mantle, where its lateral dimensions narrow considerably. This elongated density anomaly is consistent with a basement high and indicates a channelization of the Iceland plume effects. The NE-SW elongated mantle anomaly does not, however, coincide with the topographical NNE-SSW striking ridge axis. Thus, the modelled plume-affected oceanic lithosphere reveals discrepancies with the half-space cooling model. We discuss the 3D density model in terms of such spatial relations between deeper mantle anomalies and the shallow crustal structure.

Popliteal artery entrapment syndrome in a young girl

International Nuclear Information System (INIS)

Haidar, Salwa; Thomas, Karen; Miller, Stephen

2005-01-01

Popliteal artery entrapment syndrome (PAES) is well-described in adults, but is an uncommon cause of lower-limb pain in children. We present an 11.5-year-old girl with thrombosed aneurysm of the right popliteal artery, subsequently diagnosed with bilateral type I PAES. Multimodality illustration of the radiological findings is presented. (orig.)

Jan Greshoff se ‘aanval’ op Olga Kirsch as een van die hoofredes vir haar emigrasie: ’n Psigoanalitiese beskouing / Jan Greshoff’s ‘Attack’ on Olga Kirsch as One of the Main Causes of Her Emigration: A Psychoanalytical Point of View

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Minnaar Thomas

2014-11-01

Full Text Available The poet Olga Kirsch left South Africa permanently for Israel in 1948. It is evident from her poetry that her Zionism, opposition to the racism of the National Party and a failed love played a role in her decision. This article focuses on another reason - a public attack by the Dutch critic Jan Greshoff in an Afrikaans literary magazine in 1946. Using concepts from psychoanalytical theories around borderline and narcissistic personalities, as well as the effect of emigration, Kirsch’s actions are examined as a reaction to narcissistic wounding. Investigating Greshoff’s criticism gives insights into the poet’s actions and explains the hiatus before she started publishing again in Afrikaans from 1971. It is stated that the poet is not considered to be a narcissist as her oeuvre is a testimony to her empathy with others, but the healthy narcissism needed in building one’s self-esteem underwent a severe blow when Kirsch lost the man she loved and was humiliated so devastatingly by the great Dutch critic.

Ressenya a Enric Pujol (ed. & Òscar Jané (est., Antologia de memòries i dietaris personals catalans sobre la Guerra de Successió, Barcelona, Institut d’Estudis Catalans, 2014, 286 pp. ISBN: 978-84-9965-221-4

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Adrià Cases Ibáñez

2015-12-01

Full Text Available Review to Enric Pujol (ed. & Òscar Jané (est., Antologia de memòries i dietaris personals catalans sobre la Guerra de Successió, Barcelona, Institut d’Estudis Catalans, 2014, 286 pp. ISBN: 978-84-9965-221-4

Metal-organic framework MIL-101(Cr) as a sorbent of porous membrane-protected micro-solid-phase extraction for the analysis of six phthalate esters from drinking water: a combination of experimental and computational study.

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Wang, Ting; Wang, Jian; Zhang, Conglu; Yang, Zhao; Dai, Xinpeng; Cheng, Maosheng; Hou, Xiaohong

2015-08-07

An attractive metal-organic framework (MOF) MIL-101(Cr) material was synthesized at the nanoscale and applied as a sorbent in the porous membrane-protected micro-solid-phase extraction (μ-SPE) device for the pre-concentration of phthalate esters (PAEs) in drinking water samples for the first time. Parameters influencing the extraction efficiency, such as the selection of sorbent materials, pH adjustment, the effect of salt, magnetic-stirring extraction time, the desorption solvent and the desorption time, were investigated. Under the optimum conditions, the limits of detection from gas chromatography-mass spectrometric analysis for PAEs varied from 0.004 to 0.02 μg L(-1). The linear ranges were from 0.1 to 50 μg L(-1) or from 0.2 to 50 μg L(-1) for the analytes with the relative standard deviations fluctuating from 0.8 to 10.9% (n = 5). The enrichment factors (EFs) for the target PAEs were varied from 143 to 187. MIL-101(Cr) exhibited remarkable advantages compared to activated carbon and MIL-100(Fe). On the other hand, the computational method was first used to predict the adsorption of MIL-101(Cr) towards PAEs. The molecular interactions and the free binding energies between MIL-101(Cr) and PAEs were observed and calculated in terms of the molecular modeling method. MIL-101(Cr) showed high potential in the analysis of PAEs at trace levels in drinking water. The computational result was consistent with the detected enrichment factors. The computational modeling accurately predicted the extraction efficiency of MOF-based material towards the target analytes. Therefore, the combination of experimental and computational study provided a new strategy on the trace contaminant analysis.

Comb-shaped single ion conductors based on polyacrylate ethers and lithium alkyl sulfonate

International Nuclear Information System (INIS)

Sun Xiaoguang; Hou Jun; Kerr, John B.

2005-01-01

Comb-shaped single ion conductors have been synthesized by (1) sulfonation of small molecule chloroethyleneglycols, which, after ion exchange to the Li + salt were then converted to the acrylate by reaction with acryloyl chloride and copolymerized with polyethylene glycol monomethyl ether acrylate (Mn = 454, n = 8) (PAE 8 -co-E 3 SO 3 Li); (2) sulfonation of chloride end groups grafted on to prepolymers of polyacrylate ethers (PAE 8 -g-E n SO 3 Li, n = 2, 3). The highest conductivity at 25 deg. C of 2.0 x 10 -7 S cm -1 was obtained for the PAE 8 -co-E 3 SO 3 Li with a salt concentration of EO/Li = 40. The conductivity of PAE 8 -g-E 3 SO 3 Li is lower than that of PAE 8 -co-E 3 SO 3 Li at similar salt concentrations, which is related to the incomplete sulfonation of the grafted polymer that leads to a lower concentration of Li + . The addition of 50 wt.% of plasticizer, PC/EMC (1/1, v/v), to PAE 8 -g-E 2 SO 3 Li increases the ambient conductivity by three orders of magnitude, which is due to the increased ion mobility in a micro-liquid environment and an increase concentration of free ions as a result of the higher dielectric constant of the solvent. A symmetrical Li/Li cell with an electrolyte membrane consisting of 75 wt.% PC/EMC (1/1, v/v) was cycled at a current density of 100 μA cm -2 at 85 deg. C. The cycling profile showed no concentration polarization after a break-in period during the first few cycles, which was apparently due to reaction of the solvent at the lithium metal surface that reacted with lithium metal to form a stable SEI layer

Diagnosis and surgical approach of popliteal artery entrapment syndrome: a retrospective study

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Stavros Gourgiotis

2008-02-01

Full Text Available Stavros Gourgiotis1, John Aggelakas1, Nikolaos Salemis1, Charalabos Elias2, Charalabos Georgiou11Second Surgical Department, 401 General Army Hospital of Athens, Greece; 2Second Surgical Department, 417 NIMTS Veterans General Hospital of Athens, GreeceBackground: Popliteal artery entrapment syndrome (PAES is a rare but potentially limb threatening peripheral vascular disease occurring predominantly in young adults. This study is a retrospective review of 49 limbs in 38 patients with PAES treated surgically over an 8-year period.Patients and methods: From 1995 to 2002, 38 patients with a mean age of 21 years (range, 18–29 years underwent surgery for PAES at a single institution. The patients’ demographic data and clinical features are recorded. The preoperative diagnosis of PAES was made based on various combinations of investigations including positional stress test, duplex ultrasonography, computed tomography, computed tomographic angiography, and angiography. Results: Nine, 33, and 7 patients had Delaney’s type I, II, and III PAES respectively. The surgical procedures consisted of simple release of the popliteal artery in 33 limbs (67.3%, autogenous saphenous vein (ASV patch angioplasty with or without thromboendarterectomy (TEA in 5 limbs (10.2% and ASV graft interposition or bypass in 11 limbs (22.5%. At a median follow up of 34 months (range, 8–42 months, there were no postoperative complications and all the patients were cured of their symptoms.Conclusions: PAES is an unusual but important cause of peripheral vascular insufficiency especially in young patients. Early diagnosis through a combined approach is necessary for exact diagnosis. Popliteal artery release alone or with vein bypass is the treatment of choice when intervention is indicated for good operative outcome and to prevent limb loss.Keywords: popliteal artery, entrapment syndrome, diagnosis, surgery, treatment

Home of the 151st Air Refueling Wing

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History HRA Alley Public Affairs SAPR Units Contact Us Search 151st ARW: 151st ARW The Roland R. Wright woman in the profession of arms President Trump visits Roland R. Wright Air National Guard Base 151st Commentaries Women's History Month: looking around as important as looking back Veterans Day: Pay tribute with

Preparation and characterization of novel zwitterionic poly(arylene ether sulfone) ultrafiltration membrane with good thermostability and excellent antifouling properties

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Rong, Guolong; Zhou, Di; Han, Xiaocui; Pang, Jinhui

2018-01-01

Zwitterionic poly(arylene ether sulfone) (PAES-NS) was synthesized via copolymerization by using a bisphenol monomer with a pyridine group. The chemical structures of the copolymers were confirmed by using Fourier transform infrared (FTIR) and 1H nuclear magnetic resonance (NMR) spectroscopy; the copolymers showed good thermal stability. A series of polyphenysulfone (PPSU)/PAES-NS blend ultrafiltration (UF) membranes was prepared via conventional immersion precipitation phase inversion methods The morphologies of the modified membranes were investigated by scanning electron microscopy (SEM). The surface hydrophilicity of the UF membranes was studied by water contact angle measurement, indicating that the zwitterionic group increased the membrane hydrophilicity. UF of solvated model pollutants using the membranes showed a significant reduction of the irreversible adsorption of the foulants, illustrating the excellent anti-fouling properties of the membrane. The water flux of the PAES-NS membrane was significantly enhanced, being almost three times higher than that of the pristine PPSU membrane, with retention of a high rejection level. After three UF cycles, the water flux recovery of the PAES-NS membrane was as high as 96%.

Nanosuspension of Phyllanthus amarus extract for improving oral bioavailability and prevention of paracetamol induced hepatotoxicity in Sprague–Dawley rats

International Nuclear Information System (INIS)

Mishra, Shanti Bhushan; Pandey, Himanshu; Pandey, Avinash C

2013-01-01

Phyllanthus amarus (P. amarus) is commonly used for traditional Indian medicine and as dietary adjuncts for the treatment of numerous physiological disorders including hepatic disorders. Due to the poor water solubility of its major constituents such as lignans and flavonoids, its absorption upon oral administration could be limited. The present study was designed to evaluate and compare the hepatoprotective effects of the ethanolic extract of P. amarus (PAE) and its nanoparticles (PAN) on paracetamol induced acute liver toxicity in Sprague–Dawley rats. An oral dose of PAE at 125 and 250 mg kg −1 and PAN at 25 and 50 mg kg −1 showed a significant hepatoprotective effect relatively to the same extent (P −1 PAN was effectively better than 125 mg kg −1 PAE (P < 0.001), and an oral dose of PAN that is five times less than PAE could exhibit similar levels of outcomes. In conclusion, we suggest that the nanoparticles system can be applied to overcome other poorly water soluble herbal medicines and furthermore to decrease the treatment dosage. (paper)

Novel time-of-flight spectrometer for the analysis of positron annihilation induced Auger electrons

International Nuclear Information System (INIS)

Hugenschmidt, Christoph; Legl, Stefan

2006-01-01

Positron annihilation induced Auger-electron spectroscopy (PAES) has several advantages over conventional Auger-electron spectroscopy such as extremely high surface sensitivity and outstanding signal-to-noise ratio at the Auger-transition energy. In order to benefit from these prominent features a low-energy positron beam of high intensity is required for surface sensitive PAES studies. In addition, an electron energy analyzer is required, which efficiently detects the Auger electrons with acceptable energy resolution. For this reason a novel time-of-flight (TOF) spectrometer has been developed at the intense positron source NEPOMUC that allows PAES studies within short measurement time. This TOF-PAES setup combines a trochoidal filter and a flight tube in a Faraday cage in order to achieve an improved energy resolution of about 1 eV at high electron energies up to E≅1000 eV. The electron flight time is the time between the annihilation radiation at the sample and when the electron hits a microchannel plate detector at the end of the flight tube

An attempt to revisit the global biogeography of limno-terrestrial Tardigrada

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Philip J.A. PUGH

2007-09-01

Full Text Available The major increase in distribution records of limno-terrestrial tardigrades over the last ten years has enabled us to reassess the global biogeography of the Tardigrada using cluster analysis, principal components analysis and parsimony analysis of endemism (PAE. Although the new clustergram topology shows a close correlation with those we originally presented in 1998, the PAE outputs warrant a radical reinterpretation of the results as they imply that the Laurasian fauna is derived and the Gondwanan groups basal. The distribution of endemic tardigrade genera and families provides some support for this argument though the findings should be viewed with some caution as PAE has its detractors and has not been previously applied on a 'global' scale.

Physical design of the positron induced auger electron spectrometer

International Nuclear Information System (INIS)

Qin Xiubo; Jiang Xiaopan; Wang Ping; Yu Runsheng; Wang Baoyi; Wei Long

2009-01-01

Positron Annihilation Induced Auger Electron Spectroscopy (PAES) has several advantages over those excited by X-rays, high energy electrons or neutrons, such as excellent surface selectivity, high signal-to-noise ratio, low radiation damage,etc. A physical design of time of flight PAES (TOF-PAES) apparatus based on the Beijing Intense Slow Positron Beam (BIPB) is described in this paper. The positrons and electrons are transported in a 4 x 10 -3 T uniform magnetic field, and the gradient of magnetic field is designed to pluralize the Auger electrons emitted with 2π angle. The Auger electron energy is adjusted by a Faraday cage to optimize the energy resolution,which can be better than 2 eV. (authors)

Simple Model of a Photoacoustic System as a CR Circuit

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Fukuhara, Akiko; Kaneko, Fumitoshi; Ogawa, Naohisa

2012-01-01

We introduce the photoacoustic educational system (PAES), by which we can identify which gas causes the greenhouse effect in a classroom (Kaneko "et al" 2010 "J. Chem. Educ." 87 202-4). PAES is an experimental system in which a pulse of infrared (IR) is absorbed into gas as internal energy, an oscillation of pressure (sound) appears, and then we…

Hypersynchrony in MEG spectral amplitude in prospectively-identified 6-month-old infants prenatally exposed to alcohol

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Julia M. Stephen

2018-01-01

Full Text Available Early identification of children who experience developmental delays due to prenatal alcohol exposure (PAE remains a challenge for individuals who do not exhibit facial dysmorphia. It is well-established that children with PAE may still exhibit the cognitive and behavioral difficulties, and individuals without facial dysmorphia make up the majority of individuals affected by PAE. This study employed a prospective cohort design to capture alcohol consumption patterns during pregnancy and then followed the infants to 6 months of age. Infants were assessed using magnetoencephalography to capture neurophysiological indicators of brain development and the Bayley Scales of Infant Development-III to measure behavioral development. To account for socioeconomic and family environmental factors, we employed a two-by-two design with pregnant women who were or were not using opioid maintenance therapy (OMT and did or did not consume alcohol during pregnancy. Based on prior studies, we hypothesized that infants with PAE would exhibit broad increased spectral amplitude relative to non-PAE infants. We also hypothesized that the developmental shift from low to high frequency spectral amplitude would be delayed in infants with PAE relative to controls. Our results demonstrated broadband increased spectral amplitude, interpreted as hypersynchrony, in PAE infants with no significant interaction with OMT. Unlike prior EEG studies in neonates, our results indicate that this hypersynchrony was highly lateralized to left hemisphere and primarily focused in temporal/lateral frontal regions. Furthermore, there was a significant positive correlation between estimated number of drinks consumed during pregnancy and spectral amplitude revealing a dose-response effect of increased hypersynchrony corresponding to greater alcohol consumption. Contrary to our second hypothesis, we did not see a significant group difference in the contribution of low frequency to high frequency

Does food insecurity compromise maternal dietary Zinc or energy intake in favor of her child, in rural poor Mexican households? ¿En hogares rurales pobres de México, la inseguridad alimentaria compromete el consumo de zinc y energía de las madres en favor de sus hijos?

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Karla Moreno-Tamayo

2011-08-01

Full Text Available OBJECTIVE: To analyze quantitative indicators of food insecurity (FI, and estimate if FI modifies the association between maternal and child Zinc and energy intake as evidence for maternal dietary compromise in favor of her child. MATERIAL AND METHODS: Cross-sectional study (n=2 563, data derived from baseline impact evaluation of the Mexican Programa de Apoyo Alimentario. Quantitative indicators of FI were:Household food storage, maize and/or bean production, food expenditure, and spatial access to food markets. We evaluated percentage adequacy of energy (PAE and Zinc (PAZn intake. Multiple linear regression model was fitted to estimate the association between maternal and child PAE and PAZn. RESULTS: Child PAE and PAZn were positively associated with those of their mothers. None of the FI indicators modified the association between maternal and child PAE and PAZn. CONCLUSIONS: No evidence of maternal dietary compromise in favor of her child was observed using four quantitative indicators of FI in central-southern rural Mexican househods.OBJETIVO: Analizar indicadores cuantitativos de inseguridad alimentaria (IA y estimar si IA modifica la asociación del consumo de energía y zinc en madres e hijos como evidencia del compromiso de la dieta materna a favor de su hijo. MATERIAL Y MÉTODOS: Estudio transversal,información basal de la evaluación de impacto del Programa de Apoyo Alimentario. Indicadores de IA: reserva de alimentos en hogar, autoproducción maíz y/o frijol, porcentaje del gasto en alimentos y acceso físico a mercados de alimentos.Se calculó el porcentaje de adecuación del consumo energético (PAE y Zinc (PAZn (n=2 563 pares. Se estimó un modelo de regresión lineal ajustado por covariables. RESULTADOS: El PAE y PAZn de madres e hijos se asoció positivamente. Ningún indicador de IA modificó la asociación entre PAE y PAZn materno con respecto a sus hijos. CONCLUSIONES: Los indicadores de IA estudiados no modifican la relaci

Obituary: Dr. Richard Roland Baker

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Thornton R

2014-12-01

Full Text Available Richard Baker died at Easter 2007 after a very short illness. It is sad that he died so soon after his retirement from the British American Tobacco Company at the end of 2005, and just as he was beginning to enjoy his new life, even though tobacco science still had a part to play.

[Utilizing the ultraintense JanUSP laser at LLNL]. 99-ERD-049 Final LDRD Report

International Nuclear Information System (INIS)

Patel, P K; Price, D F; Mackinnon, A J; Springer, P T

2002-01-01

Recent advances in laser and optical technologies have now enabled the current generation of high intensity, ultrashort-pulse lasers to achieve focal intensities of 10 20 -10 21 W/cm 2 in pulse durations of 100-500fs. These ultraintense laser pulses are capable of producing highly relativistic plasma states with densities, temperatures, and pressures rivaling those found in the interiors of stars and nuclear weapons. Utilizing the ultraintense 100TW JanUSP laser at LLNL we have explored the possibility of ion shock heating small micron-sized plasmas to extremely high energy densities approaching 1GJ/g on timescales of a few hundred femtoseconds. The JanUSP laser delivers 10 Joules of energy in a 100fs pulse in a near diffraction-limited beam, producing intensities on target of up to 10 21 W/cm 2 . The electric field of the laser at this intensity ionizes and accelerates electrons to relativistic MeV energies. The sudden ejection of electrons from the focal region produces tremendous electrostatic forces which in turn accelerate heavier ions to MeV energies. The predicted ion flux of 1 MJ/cm 2 is sufficient to achieve thermal equilibrium conditions at high temperature in solid density targets. Our initial experiments were carried out at the available laser contrast of 10 -7 (i.e. the contrast of the amplified spontaneous emission (ASE), and of the pre-pules produced in the regenerative amplifier). We used the nuclear photoactivation of Au-197 samples to measure the gamma production above 12MeV-corresponding to the threshold for the Au-197(y,n) reaction. Since the predominant mechanism for gamma production is through the bremsstrahlung emission of energetic electrons as they pass through the solid target we were able to infer a conversion yield of several percent of the incident laser energy into electrons with energies >12MeV. This result is consistent with the interaction of the main pulse with a large pre-formed plasma. The contrast of the laser was improved to

Positron annihilation induced Auger electron spectroscopy and its implementation at accelerator based low energy positron factories

International Nuclear Information System (INIS)

Weiss, A.; Koeymen, A.R.; Mehl, D.; Lee, K.H.; Yang Gimo; Jensen, K.

1991-01-01

Positron annihilation induced auger electron spectroscopy (PAES) makes use of a beam of low energy positrons to excite Auger transitions by annihilating core electrons. The large secondary electron background usually present in Auger spectra can be eliminated by setting the positron beam energy well below the Auger electron energy. This allows true Auger lineshapes to be obtained. Further, because the positron is localized just outside the surface before it annihilates, PAES is extremely sensitive to the topmost atomic layer. Recent PAES results obtained at the University of Texas at Arlington will be presented. In addition, the use of high resolution energy analyzers with multichannel particle detection schemes to prevent problems due to the high data rates associated with accelerator based positron beams will be discussed. (orig.)

Jan van der Groen, hovenier van de Prins van Oranje. Nieuwe archiefgegevens over zijn leven

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Lenneke Berkhout

2017-08-01

Jan van der Groen was something of an odd man out among the gardeners. Having started out as a florist, he would seem to have had no experience in garden management when he was appointed head gardener. Most other gardeners had worked in the job from an early age, thereby building a wider range of horticultural skills and knowledge. It is also probable that he had little or no knowledge of geometry at a time when gardeners were increasingly being required to lay out classical gardens. On the other hand, in addition to his considerable knowledge of flowers and plants, Van der Groen was acquainted with prevailing views on ‘outdoor life’; he was familiar with the foremost gardens in France and the Dutch Republic, either from illustrations or possibly even from personal experience. In this he probably differed from other gardeners. Van der Groen did not make any garden designs. His social position was comparable to that of other gardeners: they belonged to the petit bourgeoisie, a social middle class with a modicum of property, which fell between the small, wealthy upper class and the vast mass of poor people. Nor was there any difference in terms of the subordinate position within the stadholder household and the garden management organization. All gardeners were required to render detailed accounts to the Nassause Domeinraad, the body responsible for managing the Prince of Orange’s domains. Ultimately, it was the publication of his book that set Van der Groen apart from his peers. No other court gardener ever penned such a work.

Dissolved inorganic carbon, alkalinity, temperature, salinity and other variables collected from discrete sample and profile observations using CTD, bottle and other instruments from the JAN MAYEN in the Arctic Ocean and Barents Sea from 2004-07-24 to 2004-07-31 (NODC Accession 0113566)

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National Oceanic and Atmospheric Administration, Department of Commerce — NODC Accession 0113566 includes chemical, discrete sample, physical and profile data collected from JAN MAYEN in the Arctic Ocean and Barents Sea from 2004-07-24 to...

Idade de aparecimento e desaparecimento das pontas rolândicas em 160 crianças acompanhadas ambulatorialmente: estudo atuarial Age of appearance and disappearance of rolandic spikes of 160 children: an actuarial study

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MOACIR A. BORGES

1999-09-01

Full Text Available PROPOSTA: Determinar a idade em que surgem e desaparecem as pontas rolândicas (PR em traçados eletrencefalográficos de rotina. MÉTODO: Estudo prospectivo hospitalar, baseado em 412 eletrencefalogramas de 160 crianças que frequentaram o ambulatório de neuropediatria entre as idades de 1 e 16 anos, no período de março de 1989, a março de 1998. Usou-se o sistema 10/20 para colocação dos eletrodos. As crianças foram dividas, por idade, em quatro grupos (1 a 4; 5 a 8; 9 a 16; 1 a 16 e usou-se o método de curva atuarial, considerando-se como evento, o desaparecimento da PR. RESULTADOS: PR teve distribuição entre meninos e meninas na razão de 64/36. A idade média em que surgiu a PR foi 7 anos (7,2 para homens e 6,6 para mulheres e, num pequeno grupo de crianças que tinha EEG normal anterior ao surgimento da PR, a idade média foi 6,8 anos. Após 7 anos de seguimento, a percentagem de pacientes livres de PRs era 60% para o grupo de 1 a 4 anos na admissão, 84% para os grupos de 5 a 8 anos e 9 a 16 anos. Para o grupo total (1 a 16 anos a percentagem de livres de PR, após 7 anos de seguimento, foi 78%. CONCLUSÃO: O estudo mostra que as PR surgiram, em média, aos 7 anos e têm probabilidade de desaparecimento até 7 anos de seguimento, independetemente da faixa etária de aparecimento.This study aims to determine the age at which the rolandic spikes (RS appear and disappear in routine EEGs. METHOD: It has been carried out a hospital based prospective study of 412 EEGs records of 160 children who had been assisted at the neuropediatric out-patient department during the period between March, 1989 and March,1998. Recordings were made on 8-channel instruments and 10/20 system has been to place the electrodes. The children have been divided into 4 groups, according to their age (1 to 4; 5 to 8; 9 to 16; 1 to 16, and the actuarial curve method has been used to show the disappearance of the rolandic spikes. RESULTS: RS distribution between

Mathematics intervention for children with fetal alcohol spectrum disorder: A replication and extension of the math interactive learning experience (MILE) program.

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Kully-Martens, Katrina; Pei, Jacqueline; Kable, Julie; Coles, Claire D; Andrew, Gail; Rasmussen, Carmen

2018-07-01

Individuals with fetal alcohol spectrum disorders (FASD) experience deficits in behavior, cognition, and academic functioning resulting from prenatal alcohol exposure (PAE). Although receiving intervention for developmental disabilities is a strong protective factor against negative outcomes in FASD, intervention research in this population is in its infancy. The purpose of this study was to replicate and extend a mathematics intervention, the Math Interactive Learning Experience (MILE) program, which was developed in the USA specifically for children with FASD. Twenty-eight Canadian children aged 4-10 years with confirmed PAE or an FASD diagnosis were assigned to either the MILE intervention or a contrast intervention. Following a relatively brief, individualized, one-on-one intervention, children in the MILE group demonstrated significantly greater changes in math achievement compared to the contrast group. Significant changes in other cognitive functions were not observed. Older age, lower IQ, and confirmed PAE but no FASD diagnosis were associated with greater math achievement change in the MILE group. The replication and extension of the math intervention appears to have significant, positive impact on mathematics achievement scores of children with PAE and FASD. Copyright © 2018 Elsevier Ltd. All rights reserved.

Maternal Iron Nutriture as a Critical Modulator of FASD Risk in Alcohol-Exposed Pregnancies

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Helfrich, Kaylee K.; Saini, Nipun; Kling, Pamela J.; Smith, Susan M.

2018-01-01

Alcohol consumption during pregnancy places the fetus at risk for permanent physical, cognitive, and behavioral impairments, collectively termed fetal alcohol spectrum disorders (FASD). However, prenatal alcohol exposure (PAE) outcomes vary widely, and growing evidence suggests that maternal nutrition is a modifying factor. Certain nutrients, such as iron, may modulate FASD outcomes. Untreated gestational iron deficiency (ID) causes persistent neurodevelopmental deficits in the offspring that affect many of the same domains damaged by PAE. Although chronic alcohol consumption enhances iron uptake and elevates liver iron stores in adult alcoholics, alcohol-abusing premenopausal women often have low iron reserves due to menstruation, childbirth, and poor diet. Recent investigations show that low iron reserves in during pregnancy are strongly associated with a worsening of several hallmark features in FASD including reduced growth and impaired associative learning. This review discusses recent clinical and animal model findings that maternal ID worsens fetal outcomes in response to PAE. It also discusses underlying mechanisms by which PAE disrupts maternal and fetal iron homeostasis. We suggest that alcohol-exposed, ID pregnancies contribute to the severe end of the FASD spectrum. PMID:29017023

Concentration and source identification of polycyclic aromatic hydrocarbons and phthalic acid esters in the surface water of the Yangtze River Delta, China

Institute of Scientific and Technical Information of China (English)

Lifei Zhang; Liang Dong; Lijun Ren; Shuangxin Shi; Li Zhou; Ting Zhang; Yeru Huang

2012-01-01

The pollution from polycyclic aromatic hydrocarbons (PAHs) and phthalic acid esters (PAEs) in the surface water of the rapidly urbanized Yangtze River Delta region was investigated.Fourteen surface water samples were collected in June 2010.Water samples were liquid-liquid extracted using methylene chloride and analyzed by gas chromatography-mass spectrometry.Concentrations of PAHs and PAEs ranged 12.9-638.1 ng/L and 61-28550 ng/L,respectively.Fluoranthene,naphthalene,pyrene,phenanthrene,di-2-ethylhexyl phthalate,and di-n-butyl phthalate were the most abundant compounds in the samples.The water samples were moderately Polluted with benzo[a]pyrene according to China's environmental quality standard for surface water.The two highest concentrations of PAHs and PAEs occurred in samples from Taihu Lake,Wuxi City and the western section of Yangchenghu Lake.Potential sources of Pollution at S7 were petroleum combustion and the plastics industry,and at Yangchenghu Lake were petroleum combustion and domestic waste.Pollution in samples from the Beijing-Hangzhou Grand Canal originated from diesel engines.There were no obvious sources of pollution for the other water samples.These results can be used as reference levels for future monitoring programs of pollution from PAHs and PAEs.

Experiences and attitudes about physical activity and exercise in patients with chronic pain: a qualitative interview study.

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Karlsson, Linn; Gerdle, Björn; Takala, Esa-Pekka; Andersson, Gerhard; Larsson, Britt

2018-01-01

The purpose of this study was to describe how patients with chronic pain experience physical activity and exercise (PA&E). This qualitative interview study included 16 women and two men suffering from chronic pain and referred to a multimodal pain rehabilitation program. Semi-structured interviews were conducted and qualitative content analysis was used to analyze the interviews. One main theme emerged: "To overcome obstacles and to seize opportunities to be physically active despite chronic pain." This main theme was abstracted from five themes: "Valuing a life with physical activity," "Physical activity and exercise - before and after pain," "A struggle - difficulties and challenges," "The enabling of physical activity," and "In need of continuous and active support." Although these participants valued PA&E, they seldom achieved desirable levels, and performance of PA&E was undermined by difficulties and failure. The discrepancy between the intention to perform physical activity and the physical activity accomplished could be related to motivation, self-efficacy, and action control. The participants desired high-quality interaction with healthcare providers. The findings can be applied to chronic pain rehabilitation that uses PA&E as treatment.

The use of prolotherapy in the sacroiliac joint.

Science.gov (United States)

Cusi, M; Saunders, J; Hungerford, B; Wisbey-Roth, T; Lucas, P; Wilson, S

2010-02-01

In this study the effectiveness of prolotherapy in the treatment of deficient load transfer of the sacroiliac joint (SIJ) was determined. A prospective descriptive study. Authors' private practice. 25 patients who consented to treatment and attended for at least one follow-up visit and assessment. From April 2004 to July 2007. Three injections of hypertonic dextrose solution into the dorsal interosseous ligament of the affected SIJ, under CT control, 6 weeks apart. Quebec Back Pain Disability Scale, Roland-Morris 24, Roland-Morris 24 Multiform questionnaires and clinical examination by two authors independently. All patients included in this study attended at least one follow-up visit at 3, 12 or 24 months.. The number of patients at follow-up decreased at 12 and 24 months. Functional questionnaires demonstrated significant improvements for those followed-up at 3, 12 and 24 months (pprolotherapy in private practice has shown positive clinical outcomes for the 76% of patients who attended the 3-month follow-up visit (76% at 12 months and 32% at 24 months). Similar results were found in the questionnaires (Quebec Back Pain Disability Scale, Roland-Morris 24 and Roland-Morris 24 Multiform questionnaires) at 3, 12 and 24 months.

Dissolved inorganic carbon, alkalinity, temperature, salinity and other variables collected from discrete sample and profile observations using CTD, bottle and other instruments from the JAN MAYEN in the Arctic Ocean, Barents Sea and North Greenland Sea from 2005-05-20 to 2005-06-02 (NODC Accession 0113564)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — NODC Accession 0113564 includes chemical, discrete sample, physical and profile data collected from JAN MAYEN in the Arctic Ocean, Barents Sea and North Greenland...

Energetic particle, solar wind plasma and magnetic field measurements on board Prognoz-6 during the large scale interplanetary disturbance of Jan. 3-4, 1978

International Nuclear Information System (INIS)

Kurt, V.G.; Stolpovskij, V.G.; Gombosi, T.I.; Kecskemety, K.; Somogyi, J.; Gringauz, K.I.; Kotova, G.A.; Verigin, M.I.; Styazhkin, V.A.

1980-05-01

The interplanetary shock, generated during the solar flare of Jan. 1, 1978 reached the Earth's orbit on January 3, 21sup(h) UT. Aboard Prognoz-6 satellite the fluxes and spectra of energetic electron (E>30 keV) and proton (E>500 keV) fluxes and energy spectra of solar wind ions up to 4.5 keV and magnetic field were measured, with a time resolution approximately 10 sec. Time variation of these characteristics are given including preshock and postshock frequency spectra of magnetic field fluctuations. Effective acceleration of protons in the oblique shock was observed. The mean free path of protons with E<6 MeV was determined by using the time interval of anisotropic particle flux observations as lambda approximately 0.2 a.u. (author)

MR imaging and MR angiography in popliteal artery entrapment syndrome

International Nuclear Information System (INIS)

Atilla, S.; Akpek, S.; Yuecel, C.; Tali, E.T.; Isik, S.; Ilgit, E.T.

1998-01-01

Popliteal artery entrapment (PAE) syndrome is an uncommon congenital anomaly seen in young adults causing ischemic symptoms in the lower extremities. It is the result of various types of anomalous relationships between the popliteal artery and the neighboring muscular structures. The purpose of this study was to define the role of MR imaging combined with MR angiography in the diagnosis of PAE cases. Four cases with segmental occlusion and medial displacement of popliteal artery in digital subtraction angiography (DSA) examinations were diagnosed as PAE syndrome by MR imaging and MR angiography. The DSA and MRA images are compared. All of the cases showed various degrees of abnormal intercondylar insertion of the medial head of the gastrocnemius muscle. The MR images showed detailed anatomy of the region revealing the cause of the arterial entrapment. Subclassification of the cases were done and fat tissue filling the normal localization of the muscle was evaluated. The DSA and MRA images demonstrated the length and localization of the occluded segment and collateral vascular developments equally. It is concluded that angiographic evaluation alone in PAE syndrome might result in overlooking the underlying cause of the arterial occlusion, which in turn leads to unsuccessful therapy procedures such as balloon angioplasty. Magnetic resonance imaging combined with MR angiography demonstrates both the vascular anatomy and the variations in the muscular structures in the popliteal fossa successfully, and this combination seems to be the most effective way of evaluating young adults with ischemic symptoms suggesting PAE syndrome. (orig.)

Control of enzymatic degradation of biodegradable polymers by treatment with biosurfactants, mannosylerythritol lipids, derived from Pseudozyma spp. yeast strains.

Science.gov (United States)

Fukuoka, Tokuma; Shinozaki, Yukiko; Tsuchiya, Wataru; Suzuki, Ken; Watanabe, Takashi; Yamazaki, Toshimasa; Kitamoto, Dai; Kitamoto, Hiroko

2016-02-01

Cutinase-like esterase from the yeasts Pseudozyma antarctica (PaE) shows strong degradation activity in an agricultural biodegradable plastic (BP) model of mulch films composed of poly(butylene succinate-co-adipate) (PBSA). P. antarctica is known to abundantly produce a glycolipid biosurfactant, mannosylerythritol lipid (MEL). Here, the effects of MEL on PaE-catalyzed degradation of BPs were investigated. Based on PBSA dispersion solution, the degradation of PBSA particles by PaE was inhibited in the presence of MEL. MEL behavior on BP substrates was monitored by surface plasmon resonance (SPR) using a sensor chip coated with polymer films. The positive SPR signal shift indicated that MEL readily adsorbed and spread onto the surface of a BP film. The amount of BP degradation by PaE was monitored based on the negative SPR signal shift and was decreased 1.7-fold by MEL pretreatment. Furthermore, the shape of PBSA mulch films in PaE-containing solution was maintained with MEL pretreatment, whereas untreated films were almost completely degraded and dissolved. These results suggest that MEL covering the surface of BP film inhibits adsorption of PaE and PaE-catalyzed degradation of BPs. We applied the above results to control the microbial degradation of BP mulch films. MEL pretreatment significantly inhibited BP mulch film degradation by both PaE solution and BP-degradable microorganism. Moreover, the degradation of these films was recovered after removal of the coated MEL by ethanol treatment. These results demonstrate that the biodegradation of BP films can be readily and reversibly controlled by a physical approach using MEL.

Betaine supplementation reduces congenital defects after prenatal alcohol exposure (Conference Presentation)

Science.gov (United States)

Karunamuni, Ganga; Gu, Shi; Doughman, Yong Qiu; Sheehan, Megan M.; Ma, Pei; Peterson, Lindsy M.; Linask, Kersti K.; Jenkins, Michael W.; Rollins, Andrew M.; Watanabe, Michiko

2016-03-01

Over 500,000 women per year in the United States drink during pregnancy, and 1 in 5 of this population also binge drink. As high as 20-50% of live-born children with prenatal alcohol exposure (PAE) present with congenital heart defects including outflow and valvuloseptal anomalies that can be life-threatening. Previously we established a model of PAE (modeling a single binge drinking episode) in the avian embryo and used optical coherence tomography (OCT) imaging to assay early-stage cardiac function/structure and late-stage cardiac defects. At early stages, alcohol/ethanol-exposed embryos had smaller cardiac cushions and increased retrograde flow. At late stages, they presented with gross morphological defects in the head and chest wall, and also exhibited smaller or abnormal atrio-ventricular (AV) valves, thinner interventricular septae (IVS), and smaller vessel diameters for the aortic trunk branches. In other animal models, the methyl donor betaine (found naturally in many foods such as wheat bran, quinoa, beets and spinach) ameliorates neurobehavioral deficits associated with PAE but the effects on heart structure are unknown. In our model of PAE, betaine supplementation led to a reduction in gross structural defects and appeared to protect against certain types of cardiac defects such as ventricular septal defects and abnormal AV valvular morphology. Furthermore, vessel diameters, IVS thicknesses and mural AV leaflet volumes were normalized while the septal AV leaflet volume was increased. These findings highlight the importance of betaine and potentially methylation levels in the prevention of PAE-related birth defects which could have significant implications for public health.

Solid-phase microextraction of phthalate esters in water sample using different activated carbon-polymer monoliths as adsorbents.

Science.gov (United States)

Lirio, Stephen; Fu, Chung-Wei; Lin, Jhih-Yun; Hsu, Meng-Ju; Huang, Hsi-Ya

2016-07-13

In this study, the application of different activated carbon-polymer (AC-polymer) monoliths as adsorbents for the solid-phase microextraction (SPME) of phthalate esters (PAEs) in water sample were investigated. The activated carbon (AC) was embedded in organic polymers, poly(butyl methacrylate-co-ethylene dimethacrylate) (poly(BMA-EDMA)) or poly(styrene-co-divinylbenzene) (poly(STY-DVB)), via a 5-min microwave-assisted or a 15-min water bath heating polymerization. Preliminary investigation on the performance of the native poly(BMA-EDMA) and poly(STY-DVB) demonstrated remarkable adsorption efficiencies for PAEs. However, due to the strong hydrophobic, π-π, and hydrogen bonding interactions between the analytes and polymers, low extraction recoveries were achieved. In contrast, the presence of AC in native polymers not only enhanced the adsorption efficiencies but also assisted the PAE desorption, especially for AC-poly(STY-DVB) with extraction recovery ranged of 76.2-99.3%. Under the optimized conditions, the extraction recoveries for intra-, inter-day and column-to-column were in the range of 76.5-100.8% (<3.7% RSDs), 77.2-97.6% (<5.6% RSDs) and 75.5-99.7% (<6.2% RSDs), respectively. The developed AC-poly(STY-DVB) monolithic column showed good mechanical stability, which can be reused for more than 30 extraction times without any significant loss in the extraction recoveries of PAEs. The AC-poly(STY-DVB) monolithic column was successfully applied in SPME of PAEs in water sample with extraction recovery ranged of 78.8%-104.6% (<5.5% RSDs). Copyright © 2016 Elsevier B.V. All rights reserved.

United States Air Force Graduate Student Summer Support Program (1987). Program Management Report.

Science.gov (United States)

1987-12-01

Psychology, 1987 Dept. of Psychology Specialty: Psychology University of Florida Assigned: SAM Gainesville, FL 32611 , (904) 392-0605 Roland Medellin Degree...USAFSAM Centrifuge 55 Methods of Quantifying and Enhancing Roland A. Medellin Reactive Oxygen Species Production 56 Applications of Differential Geometry...Strohmayer LRS Spectra 91 Centrifuge Modeling of Projectile Teresa A. Taylor Penetration in Dry, Granular Soil 92 Optical Interconnections for Digital lien N

Roland-Morris Disability Questionnaire and Oswestry Disability Index: Which Has Better Measurement Properties for Measuring Physical Functioning in Nonspecific Low Back Pain? Systematic Review and Meta-Analysis.

Science.gov (United States)

Chiarotto, Alessandro; Maxwell, Lara J; Terwee, Caroline B; Wells, George A; Tugwell, Peter; Ostelo, Raymond W

2016-10-01

Physical functioning is a core outcome domain to be measured in nonspecific low back pain (NSLBP). A panel of experts recommended the Roland-Morris Disability Questionnaire (RMDQ) and Oswestry Disability Index (ODI) to measure this domain. The original 24-item RMDQ and ODI 2.1a are recommended by their developers. The purpose of this study was to evaluate whether the 24-item RMDQ or the ODI 2.1a has better measurement properties than the other to measure physical functioning in adult patients with NSLBP. Bibliographic databases (MEDLINE, Embase, CINAHL, SportDiscus, PsycINFO, and Google Scholar), references of existing reviews, and citation tracking were the data sources. Two reviewers selected studies performing a head-to-head comparison of measurement properties (reliability, validity, and responsiveness) of the 2 questionnaires. The COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) checklist was used to assess the methodological quality of these studies. The studies' characteristics and results were extracted by 2 reviewers. A meta-analysis was conducted when there was sufficient clinical and methodological homogeneity among studies. Nine articles were included, for a total of 11 studies assessing 5 measurement properties. All studies were classified as having poor or fair methodological quality. The ODI displayed better test-retest reliability and smaller measurement error, whereas the RMDQ presented better construct validity as a measure of physical functioning. There was conflicting evidence for both instruments regarding responsiveness and inconclusive evidence for internal consistency. The results of this review are not generalizable to all available versions of these questionnaires or to patients with specific causes for their LBP. Based on existing head-to-head comparison studies, there are no strong reasons to prefer 1 of these 2 instruments to measure physical functioning in patients with NSLBP, but studies of higher

Phosphorus Acquisition Efficiency Related to Root Traits: Is Mycorrhizal Symbiosis a Key Factor to Wheat and Barley Cropping?

Science.gov (United States)

Campos, Pedro; Borie, Fernando; Cornejo, Pablo; López-Ráez, Juan A.; López-García, Álvaro; Seguel, Alex

2018-01-01

Wheat (Triticum aestivum L.) and barley (Hordeum vulgare L.) are major crops cultivated around the world, thus playing a crucial role on human diet. Remarkably, the growing human population requires a significant increase in agricultural production in order to feed everybody. In this context, phosphorus (P) management is a key factor as it is component of organic molecules such as nucleic acids, ATP and phospholipids, and it is the most abundant macronutrient in biomass after nitrogen (N), although being one of the scarcest elements in the lithosphere. In general, P fertilization has low efficiency, as only a fraction of the applied P is acquired by roots, leaving a substantial amount to be accumulated in soil as not readily available P. Breeding for P-efficient cultivars is a relatively low cost alternative and can be done through two mechanisms: i) improving P use efficiency (PUE), and/or ii) P acquisition efficiency (PAE). PUE is related to the internal allocation/mobilization of P, and is usually represented by the amount of P accumulated per biomass. PAE relies on roots ability to acquire P from the soil, and is commonly expressed as the relative difference of P acquired under low and high P availability conditions. In this review, plant adaptations related to improved PAE are described, with emphasis on arbuscular mycorrhizal (AM) symbiosis, which is generally accepted to enhance plant P acquisition. A state of the art (1980–2018) of AM growth responses and P uptake in wheat and barley is made to discuss about the commonly accepted growth promoting effect and P increased uptake by AM fungi and the contrasting evidence about the generally accepted lack of positive responses in both plant species. Finally, the mechanisms by which AM symbiosis can affect wheat and barley PAE are discussed, highlighting the importance of considering AM functional diversity on future studies and the necessity to improve PAE definition by considering the carbon trading between

Adenomatous-Dominant Benign Prostatic Hyperplasia (AdBPH) as a Predictor for Clinical Success Following Prostate Artery Embolization: An Age-Matched Case–Control Study

Energy Technology Data Exchange (ETDEWEB)

Little, M. W., E-mail: m.little@doctors.org.uk; Boardman, P.; Macdonald, A. C.; Taylor, N.; Macpherson, R. [Oxford University Hospitals NHS Foundation Trust, Department of Radiology, Churchill Hospital (United Kingdom); Crew, J. [Oxford University Hospitals NHS Foundation Trust, Department of Urology, Churchill Hospital (United Kingdom); Tapping, C. R., E-mail: crtapping@doctors.org.uk [Oxford University Hospitals NHS Foundation Trust, Department of Radiology, Churchill Hospital (United Kingdom)

2017-05-15

PurposeTo investigate the clinical impact of performing prostate artery embolization (PAE) on patients with adenomatous-dominant benign prostatic hyperplasia (AdBPH).Materials and MethodsTwelve patients from the ongoing proSTatic aRtery EmbolizAtion for the treatMent of benign prostatic hyperplasia (STREAM) trial were identified as having AdBPH; defined as two or more adenomas within the central gland of ≥1 cm diameter on multi-parametric MRI (MP-MRI). These patients were age-matched with patients from the STREAM cohort, without AdBPH. Patients were followed up with repeat MP-MRI at 3 months and 1 year. International prostate symptom score (IPSS), international index for erectile function (IIEF), and quality of life assessment from the IPSS and EQ-5D-5S questionnaires were recorded pre-PAE and at 6 weeks, 3 months, and 1 year.ResultsThe mean age of patients was 68 (61–76). All patients had PAE as a day-case procedure. The technical success in the cohort was 23/24 (96%). There was a significant reduction in prostate volume following embolization with a median reduction of 34% (30–55) in the AdBPH group, compared to a mean volume reduction of 22% (9–44) in the non-AdBPH group (p = 0.04). There was a significant reduction in IPSS in the AdBPH group following PAE when compared with the control group [AdBPH median IPSS 8 (3–15) vs. non-AdBPH median IPSS 13 (8–18), p = 0.01]. IPSS QOL scores significantly improved in the AdBPH group (p = 0.007). There was no deterioration in sexual function in either group post-PAE.ConclusionsThis is the first time that AdBPH has been identified as being a predictor of clinical success following PAE.

Adenomatous-Dominant Benign Prostatic Hyperplasia (AdBPH) as a Predictor for Clinical Success Following Prostate Artery Embolization: An Age-Matched Case–Control Study

International Nuclear Information System (INIS)

Little, M. W.; Boardman, P.; Macdonald, A. C.; Taylor, N.; Macpherson, R.; Crew, J.; Tapping, C. R.

2017-01-01

PurposeTo investigate the clinical impact of performing prostate artery embolization (PAE) on patients with adenomatous-dominant benign prostatic hyperplasia (AdBPH).Materials and MethodsTwelve patients from the ongoing proSTatic aRtery EmbolizAtion for the treatMent of benign prostatic hyperplasia (STREAM) trial were identified as having AdBPH; defined as two or more adenomas within the central gland of ≥1 cm diameter on multi-parametric MRI (MP-MRI). These patients were age-matched with patients from the STREAM cohort, without AdBPH. Patients were followed up with repeat MP-MRI at 3 months and 1 year. International prostate symptom score (IPSS), international index for erectile function (IIEF), and quality of life assessment from the IPSS and EQ-5D-5S questionnaires were recorded pre-PAE and at 6 weeks, 3 months, and 1 year.ResultsThe mean age of patients was 68 (61–76). All patients had PAE as a day-case procedure. The technical success in the cohort was 23/24 (96%). There was a significant reduction in prostate volume following embolization with a median reduction of 34% (30–55) in the AdBPH group, compared to a mean volume reduction of 22% (9–44) in the non-AdBPH group (p = 0.04). There was a significant reduction in IPSS in the AdBPH group following PAE when compared with the control group [AdBPH median IPSS 8 (3–15) vs. non-AdBPH median IPSS 13 (8–18), p = 0.01]. IPSS QOL scores significantly improved in the AdBPH group (p = 0.007). There was no deterioration in sexual function in either group post-PAE.ConclusionsThis is the first time that AdBPH has been identified as being a predictor of clinical success following PAE.

High energy resolution and first time-dependent positron annihilation induced Auger electron spectroscopty

International Nuclear Information System (INIS)

Mayer, Jakob

2010-01-01

It was the aim of this thesis to improve the existing positron annihilation induced Auger spectrometer at the highly intense positron source NEPOMUC (NEutron induced POsitron source MUniCh) in several ways: Firstly, the measurement time for a single spectrum should be reduced from typically 12 h to roughly 1 h or even less. Secondly, the energy resolution, which amounted to ΔE/E∼10%, should be increased by at least one order of magnitude in order to make high resolution positron annihilation induced Auger spectroscopy (PAES)-measurements of Auger transitions possible and thus deliver more information about the nature of the Auger process. In order to achieve these objectives, the PAES spectrometer was equipped with a new electron energy analyzer. For its ideal operation all other components of the Auger analysis chamber had to be adapted. Particularly the sample manipulation and the positron beam guidance had to be renewed. Simulations with SIMION registered ensured the optimal positron lens parameters. After the adjustment of the new analyzer and its components, first measurements illustrated the improved performance of the PAES setup: Firstly, the measurement time for short overview measurements was reduced from 3 h to 420 s. The measurement time for more detailed Auger spectra was shortened from 12 h to 80 min. Secondly, even with the reduced measurement time, the signal to noise ratio was also enhanced by one order of magnitude. Finally, the energy resolution was improved to ΔE/E 2,3 VV-transition with PAES. Thus, within this thesis two objectives were achieved: Firstly, the PAES spectrometer was renewed and improved by at least one order of magnitude with respect to the signal to noise ratio, the measurement time and the energy resolution. Secondly, several measurements have been carried out, demonstrating the high performance of the spectrometer. Amongst them are first dynamic PAES measurements and a high resolution measurement of the CuM 2,3 VV

The effects of phthalate and nonylphenol exposure on body size and secondary sexual characteristics during puberty.

Science.gov (United States)

Hou, Jia-Woei; Lin, Ching-Ling; Tsai, Yen-An; Chang, Chia-Huang; Liao, Kai-Wei; Yu, Ching-Jung; Yang, Winnie; Lee, Ming-Jun; Huang, Po-Chin; Sun, Chien-Wen; Wang, Yin-Han; Lin, Fang-Ru; Wu, Wen-Chiu; Lee, Meng-Chih; Pan, Wen-Harn; Chen, Bai-Hsiun; Wu, Ming-Tsang; Chen, Chu-Chih; Wang, Shu-Li; Lee, Ching-Chang; Hsiung, Chao Agnes; Chen, Mei-Lien

2015-10-01

Some phthalic acid esters (PAEs) and nonylphenol (NP) are endocrine-disrupting chemicals (EDCs) that are widely used in consumer products. Consequently, the general population is exposed simultaneously to both groups of chemicals. To investigate the single- and co-exposure effects of PAEs (DMP, DEP, DnBP, DiBP, BBzP, and DEHP) and NP on obesity and pubertal maturity to compare the body sizes of general adolescents with the complainants of the phthalate-tainted foods scandal that occurred in Taiwan. This study included 270 general adolescents aged 6.5-15.0 years and 38 complainants aged 6.5-8.5 years. Nine metabolites of the five PAEs and of NP were measured in urine. We used a questionnaire to evaluate pubertal maturity, measured anthropometric indices (APs) to assess body size, and collected urine samples to measure the two groups of chemicals. We found that urinary PAE metabolite concentrations (specifically, metabolites of DEP, DnBP, DiBP, and DEHP) were positively associated with the APs for abdominal obesity (including skinfold thickness, waist circumference, waist-to-height ratio, and waist-to-hip) and indicated a dose-response relationship. Mono-methyl phthalate (MMP) exposure was inversely associated with pubarche among boys. The daily intake of DEHP in general adolescents exceeded the reference doses (RfD-20 μg/kgbw/day) and tolerable daily intake (TDI-50 μg/kgbw/day) by 3.4% and 0.4%, respectively. No associations were observed between NP exposure or co-exposure and the APs or pubertal maturity. No significant differences were observed between general adolescents and the complainants with regard to weight, height, or BMI. The study suggests that PAE (specifically, DEP, DnBP, DiBP, and DEHP) exposure is associated with abdominal obesity in adolescents and that the APs for abdominal obesity are more sensitive than BMI for measuring obesity among adolescents. We suggest that the RfD and TDI for PAEs should be revised to provide sufficient protection

Spatial audio reproduction with primary ambient extraction

CERN Document Server

He, JianJun

2017-01-01

This book first introduces the background of spatial audio reproduction, with different types of audio content and for different types of playback systems. A literature study on the classical and emerging Primary Ambient Extraction (PAE) techniques is presented. The emerging techniques aim to improve the extraction performance and also enhance the robustness of PAE approaches in dealing with more complex signals encountered in practice. The in-depth theoretical study helps readers to understand the rationales behind these approaches. Extensive objective and subjective experiments validate the feasibility of applying PAE in spatial audio reproduction systems. These experimental results, together with some representative audio examples and MATLAB codes of the key algorithms, illustrate clearly the differences among various approaches and also help readers gain insights on selecting different approaches for different applications.

PRICE ON THE ORGANIC FOOD MARKET

Directory of Open Access Journals (Sweden)

GEORGE ATANASOAIE

2012-12-01

Full Text Available The main objective of this paper is to present prices on PAE market (PAE- organic foods market. Prices are analyzed in terms of importance and the main factors that contribute to their establishment (quality of products, distribution channels, certification and eco-labeling system, customer segments and market development stage. This paper is based on the investigation of secondary sources, of specialized literature related to PAE consumers. The paper shows that are used three strategic options of prices: prices with high rigidity located in a low or high level and fluctuating prices, characterized by variations on short periods of time. Price is a very important barrier to market development but this importance can be mitigated through appropriate communication policies with the market, which are essential especially for markets in early stages of development.

Biomechanical and morphological multi-parameter photoacoustic endoscope for identification of early esophageal disease

Science.gov (United States)

Jin, Dayang; Yang, Fen; Chen, Zhongjiang; Yang, Sihua; Xing, Da

2017-09-01

The combination of phase-sensitive photoacoustic (PA) imaging of tissue viscoelasticity with the esophagus-adaptive PA endoscope (PAE) technique allows the characterization of the biomechanical and morphological changes in the early stage of esophageal disease with high accuracy. In this system, the tissue biomechanics and morphology are obtained by detecting the PA phase and PA amplitude information, respectively. The PAE has a transverse resolution of approximately 37 μm and an outer diameter of 1.2 mm, which is suitable for detecting rabbit esophagus. Here, an in-situ biomechanical and morphological study of normal and diseased rabbit esophagus (tumors of esophagus and reflux esophagitis) was performed. The in-situ findings were highly consistent with those observed by histology. In summary, we demonstrated the potential application of PAE for early clinical detection of esophageal diseases.

Uncommon Diseases of The Popliteal Artery: A Pictorial Review

Directory of Open Access Journals (Sweden)

Mohamed Jarraya

2016-08-01

Full Text Available Abstract Uncommon diseases of the popliteal artery include cystic adventitial disease, popliteal artery entrapment syndrome (PAES and popliteal artery aneurysm (PAA. Because all of these conditions may present with pain or intermittent claudication, imaging is crucial for differentiating them and directing management. Delayed diagnosis can lead to major complications, including acute limb ischemia. Our aim is to provide an illustrative overview of these conditions in order to make radiologists aware of them and avoid misdiagnosis for timely appropriate management. Teaching Points • Cystic adventitial disease diagnosis is based on evidence of cysts within artery walls. • A variety of anatomic variations may result in PAES. • PAES may be bilateral. • PAA is most commonly encountered in men. • Acute complications of PAA include acute thrombosis and distal embolization.

Collaboration between physician Emerich Lindenmayer and architect Jan Nevole in restoring the Sokobanja Turkish bath

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Mitrović Gordana

2015-01-01

Full Text Available The Sokobanja Turkish bath is an exceptional example of twosection baths and quite particular in its style, structure type and technology used. It is one of the two of the same type that remained in Serbia and the only one that has retained its original function. About its construction we learn from the Vidin sanjak defter from the second half of the 16th century. In the lavish built heritage inventory, Turkish baths are quite unique secular public structures, playing a prominent role in the development of health culture. Based upon their specific function, these baths possess a special architectural expression, are often monumental, decorative and imaginative in their forms and ornamentation. Prince Miloš initiated repair works of the Soko Banja baths and spa springs immediately after the settlement became a part of the Serbian Principality in 1834. When work on restoring the men’s baths started, a separate room with a tub was built for Prince Miloš, while the women’s bath remained in ruins. In 1847, the Ministry of Interior sent Dr Emerich Lindenmayer and architect Jan Nevole, as an expert team, to assess the state of the hammam so that it could be included in the undertakings funded from the state budget. After the assessment and review of the existing issues and upon a detailed report submitted to the Ministry of Interior, complex repairs were conducted in 1850, according to Nevole’s architectural design and his constant supervision. The approach implemented in the architectural renovation process was based on highly regarded principles of the time, thus preserving both the hammam’s original function and its valuable architecture.

Transcultural Flow of Demure Aesthetics: Examining Cultural Globalisation through Gothic & Lolita Fashion

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Masafumi Monden

2008-12-01

Full Text Available The process of cultural globalisation does not always imply cultural homogenisation. Rather, it can be seen as a process of cultural ‘glocalisation’ and hybridisation where cultures continuously interact with and interpret each other to engender a hybrid cultural form. As Arjun Appadurai (1993 contends, neither centrality nor peripherality of culture exists in the context of cultural globalisation. Rather, transnational cultural forms are likely to circulate in multiple directions. This is particularly evident when examining Gothic & Lolita – a Japanese fashion trend which has emerged since the late 1990s. Applying Jan Nederveen Pieterse’s theory of ‘globalisation as hybridisation’ (2004, and Roland Robertson’s concept of ‘glocalisation’ (1995, this article attempts to explore how this fashion trend manifests the process of cultural ‘glocalisation’, hybridisation, and interaction through the localisation of Western Goth subculture and especially, historical European dress styles in Japan. In addition, it explores how the fashion signifies the idea of ‘reverse’ flow of culture through an ethnographic observation of an English-speaking online community devoted to the trend. The analysis of the online community also seeks to establish the idea that this transnational cultural flow serves as an alternative to the local culture.

Deficits in response inhibition correlate with oculomotor control in children with fetal alcohol spectrum disorder and prenatal alcohol exposure.

Science.gov (United States)

Paolozza, Angelina; Rasmussen, Carmen; Pei, Jacqueline; Hanlon-Dearman, Ana; Nikkel, Sarah M; Andrew, Gail; McFarlane, Audrey; Samdup, Dawa; Reynolds, James N

2014-02-01

Children with fetal alcohol spectrum disorder (FASD) or prenatal alcohol exposure (PAE) frequently exhibit impairment on tasks measuring inhibition. The objective of this study was to determine if a performance-based relationship exists between psychometric tests and eye movement tasks in children with FASD. Participants for this dataset were aged 5-17 years and included those diagnosed with an FASD (n=72), those with PAE but no clinical FASD diagnosis (n=21), and typically developing controls (n=139). Participants completed a neurobehavioral test battery, which included the NEPSY-II subtests of auditory attention, response set, and inhibition. Each participant completed a series of saccadic eye movement tasks, which included the antisaccade and memory-guided tasks. Both the FASD and the PAE groups performed worse than controls on the subtest measures of attention and inhibition. Compared with controls, the FASD group made more errors on the antisaccade and memory-guided tasks. Among the combined FASD/PAE group, inhibition and switching errors were negatively correlated with direction errors on the antisaccade task but not on the memory-guided task. There were no significant correlations in the control group. These data suggests that response inhibition deficits in children with FASD/PAE are associated with difficulty controlling saccadic eye movements which may point to overlapping brain regions damaged by prenatal alcohol exposure. The results of this study demonstrate that eye movement control tasks directly relate to outcome measures obtained with psychometric tests that are used during FASD diagnosis, and may therefore help with early identification of children who would benefit from a multidisciplinary diagnostic assessment. Copyright © 2013 Elsevier B.V. All rights reserved.

Roland Peets : Piirivalvur on samasugune teenindaja nagu poemüüjagi / Roland Peets ; interv. Erik Kalda

Index Scriptorium Estoniae

Peets, Roland, 1957-

2000-01-01

Ida-Viru piirivalvepiirkonna ülem usub, et paari aasta pärast on Eesti piirivalve valmis valvama EL-i idapiiri. Piirivalve peamised probleemid Eesti-Vene piiril. Ilmunud ka: Severnoje Poberezhje 4. nov. lk. 5

Densely quaternized poly(arylene ether)s with distinct phase separation for highly anion-conductive membranes

Science.gov (United States)

Hu, Yuanfang; Wang, Bingxi; Li, Xiao; Chen, Dongyang; Zhang, Weiying

2018-05-01

To develop high performance anion exchange membranes (AEMs), a novel bisphenol monomer bearing eight benzylmethyl groups at the outer edge of the molecule was synthesized, which after condensation polymerization with various amounts of 4,4‧-dihydroxydiphenylsulfone and 4,4‧-difluorobenzophenone yielded novel poly(arylene ether)s with densely located benzylmethyl groups. These benzylmethyl groups were then converted to quaternary ammonium groups by radical-initiated bromination and quaternization in tandem, leading to the emergence of densely quaternized poly(arylene ether sulfone)s (QA-PAEs) with controlled ion exchange capacities (IECs) ranging from 1.61 to 2.32 mmol g-1. Both small-angle X-ray scattering (SAXS) and transmission electron microscopy (TEM) studies revealed distinct phase separation in the QA-PAEs. The QA-PAE-40 with an IEC of 2.32 mmol g-1 exhibited a Br- conductivity of 9.2 mS cm-1 and a SO42- conductivity of 14.0 mS cm-1 at room temperature, much higher than those of a control membrane with a similar IEC but without obvious phase separation. Therefore, phase separation of AEMs was validated to be advantageous for the efficient conducting of anions. The experimental results also showed that the QA-PAEs were promising AEM materials, especially for non-alkaline applications.

Influence of pilates mat and apparatus exercises on pain and balance of businesswomen with chronic low back pain.

Science.gov (United States)

Lee, Chae-Woo; Hyun, Ju; Kim, Seong Gil

2014-04-01

[Purpose] The purpose of this study was to examine the influence of mat Pilates and apparatus Pilates on pain and static balance of businesswomen with chronic back pain. [Subjects and Methods] Participants were randomly allocated to Pilates mat exercises (PME) or Pilates apparatus exercise (PAE), and performed the appropriate Pilates exercises 3 days per week for 8 weeks. In order to measure the improvement in the participants' static balance ability as a result of the exercise, the sway length and sway velocity of the subjects were measured before and after the experiment while the subjects stood on a Balance Performance Monitor (BPM) facing the front wall for 30 seconds with their eyes open. The visual analogue scale (VAS) was used to measure the degree of pain. [Results] The VAS score, sway length, and sway velocity of both groups decreased significantly after the experiment, but the PME group showed a greater decrease than the PAE group. [Conclusion] PME showed greater improvement in pain level and balance compared with PAE in this research. Since the subjects of this study were patients with low back pain, PME is assumed to have been more suitable and effective because it uses body weight to strengthen core muscles rather than heavier apparatuses as in PAE.

Relationships between self-determination theory and theory of planned behavior applied to physical activity and exercise behavior in chronic pain.

Science.gov (United States)

Brooks, Jessica M; Iwanaga, Kanako; Chiu, Chung-Yi; Cotton, Brandi Parker; Deiches, Jon; Morrison, Blaise; Moser, Erin; Chan, Fong

2017-08-01

This study examined the relationships between self-determination theory (SDT) and theory of planned behavior (TpB) applied to physical activity and exercise behavior (PA&E) in people with chronic pain. Two hundred and eleven adults with chronic musculoskeletal pain (28 males and 183 females, age range 18 to 82 years, mean age 43 years) were recruited from online support groups and clinic networks in the United States. Participants completed SDT measures relevant to PA&E on perceived autonomy support, autonomy, competence, and relatedness, as well as TpB measures relevant to PA&E on intention, attitudes, subjective norms, and perceived behavioral control. Correlational techniques and canonical correlation analysis were performed to examine the relationships and variance within and between theoretical dimensions. Overall, the SDT set accounted for 37% of the TpB variance and the TpB set accounted for 32% of the SDT set variance. The results indicate there are statistical similarities and differences between concepts in SDT and TpB models for PA&E. Using both empirical guidance and clinical expertise, researchers and practitioners should attempt to select and integrate non-redundant and complementary components from SDT, TpB, and other related health behavior theories.

Subcellular distribution and uptake mechanism of di-n-butyl phthalate in roots of pumpkin (Cucurbita moschata) seedlings.

Science.gov (United States)

Lin, Qingqi; Yang, Xiuhong; Huang, Xiongfei; Wang, Shizhong; Chao, Yuanqing; Qiu, Rongliang

2016-01-01

Phthalate acid esters (PAEs) are of particular concern due to their potential environmental risk to human and nonhuman organisms. Although uptake of PAEs by plants has been reported by several researchers, information about the intracellular distribution and uptake mechanisms of PAEs is still lacking. In this study, a series of hydroponic experiments using intact pumpkin (Cucurbita moschata) seedlings was conducted to investigate how di-n-butyl phthalate (DnBP), one of the most frequently identified PAEs in the environment, enters and is distributed in roots. DnBP was transported into subcellular tissues rapidly in the initial uptake period (<12 h). More than 80% of DnBP was detected in the cell walls and organelles, which suggests that DnBP is primarily accumulated in these two fractions due to their high affinity to DnBP. The kinetics of DnBP uptake were fitted well with the Michaelis-Menten equation, suggesting that a carrier-mediated process was involved. The application of 2,4-dinitrophenol and sodium vanadate reduced the uptake of DnBP by 37 and 26%, respectively, while aquaporin inhibitors, silver and glycerol, had no effect on DnBP uptake. These data demonstrated that the uptake of DnBP included a carrier-mediated and energy-dependent process without the participation of aquaporins.

[Analysis of phthalate esters in plastic-packaging bags on-line sample stacking-microemulsion electrokinetic chromatography].

Science.gov (United States)

Xiao, Jia; Huang, Ying; Wang, Minyi; Chen, Guonan

2012-09-01

Two convenient, effective, and reproducible methods using microemulsion electrokinetic chromatography (MEEKC)-normal stacking mode (NSM) and reversed electrode polarity stacking mode (REPSM) were developed for the on-line sample stacking of phthalate esters (PAEs). REPSM coupled with MEEKC increased the sensitivity of 937.5 to 7,143 times for four PAEs compared to the conventional MEEKC. The separating conditions in the MEEKC method were studied, and many factors influencing the two sample stacking processes were investigated in detail. The optimum sample matrices for the two stacking methods were as follows: 30 mmol/L sodium cholate (SC) and 30.0 mmol/L borate (pH 8.5). Additionally, sample injections as large as 3.45 kPa x 40 s and 3.45 kPa x 90 s were applied for NSM-MEEKC and REPSM-MEEKC, respectively. The linear relationship and reproducibility were also examined. Under the optimum conditions, the detection limits (S/N = 3) of the PAEs were in the ranges of 0.021 - 0.33 mg/L and 0.7 - 4 microg/L for NSM-MEEKC and REPSM-MEEKC, respectively. The proposed REPSM-MEEKC has been successfully applied to determine PAEs in plastic-packaging bags, and the spiked recoveries were in the range of 89.1% - 105.6% with satisfactory results.

The joint action of destruxins and botanical insecticides (rotenone, azadirachtin and paeonolum) against the cotton aphid, Aphis gossypii Glover.

Science.gov (United States)

Yi, Fei; Zou, Chunhua; Hu, Qiongbo; Hu, Meiying

2012-06-18

The joint action of destruxins and three botanical insecticides, rotenone (Rot), azadirachtin (Aza) and paeonolum (Pae) against the cotton aphid, Aphis gossypii, was bioassayed. In laboratory experiment, several synergistic groups of destruxins with botanical insecticides were found by means of Sun's Co-toxicity Coefficients (CTC) and Finney's Synergistic Coefficient (SC). The best synergistic effect was discovered in the ratio group Des/Rot 1/9 with the CTC or SC and LC₅₀ values of 479.93 or 4.8 and 0.06 μg/mL, respectively. The second and third synergistic effects were recorded in the ratio groups Des/Rot 7/3 and 9/1. Although the ratio groups Des/Aza 6/4, Des/Pae 4/6, 3/7 and 2/8 indicated synergism by Sun's CTC, they were determined as additive actions by Finney's SC. Additive actions were also found in most of the ratio groups, but antagonism were recorded only in three ratio groups: Des/Pae 9/1, 7/3 and 6/4. In greenhouse tests, the highest mortality was 98.9% with the treatment Des/Rot 1/9 at 0.60 μg/mL, meanwhile, the treatments Des/Pae 4/6 and Des/Aza 6/4 had approximately 88% mortality.

Pesan Sosial dalam Foto Jurnalistik (Analisis Semiotika dalam Buku ‘Jakarta Estetika Banal’, Bab I, III, V, dan VII

Directory of Open Access Journals (Sweden)

Jaka Priyo Nuswantara

2014-01-01

Full Text Available This study aims to determine the meaning of denotation and connotation, and social message in the book 'Aesthetics Jakarta Banal', Chapter I, III, V, and VII. The author uses the theory Semiotics of Roland Barthes. Where Semiotics of Roland Barthes uses two stages of analysis denotation and connotation. The research method used is a Roland Barthes semiotic analysis method on the basis that this study analyzes the messages conveyed in the book 'Aesthetics Jakarta Banal', which gives an explanation and overview of issues related to the formulation. Inferred outline text analysis results indicate that the social life of silence in the city with the concept of light to be seen. Of all the images examined, the object edges and political society into something dominant to be something that should be understood by the reader.

Riigi teaduspreemiate 2003 kandidaadid / Villi Ehatamm

Index Scriptorium Estoniae

Ehatamm, Villi

2003-01-01

2003. a. teaduspreemia kandidaadid: J. Einasto, A.-E. Kaasik, R. Hagelberg, H. Rätsep, R. Pullat, M. Kilp, V. Laan, P. Normak, S. Keevallik, V. Hižnjakov, M. Selg, T. Pehk, T. Rang, M. Mihkla, A. Eek, E. Meister, H.-J. Kaalep, J. Harro, A. Metspalu, T. Jürimäe, J. Haberman, A. Miidel, T. Nõges, E. Pihu, A. Raukas, R. Gross, T. Paaver, A. Valdmann, Ü. Tamm, M. Mandre, K. Ots, H. Pärn, J. Klõseiko, T. Rajasalu, V. Vensel, E. Berg, J. Reiljan, U. Varblane, K. Katus, A. Puur, A. Põldma, K. Rebane, M. Hallik, M. Must, A. Univere, E. Juhkam, I. Käsi, V. Lonn, E. Niit, K. Kirme

Radiodermitis After Prostatic Artery Embolization: Case Report and Review of the Literature

International Nuclear Information System (INIS)

Laborda, Alicia; Assis, Andre Moreira De; Ioakeim, Ignatios; Sánchez-Ballestín, María; Carnevale, Francisco Cesar; Gregorio, Miguel Angel De

2015-01-01

Prostate artery embolization (PAE) is a technically demanding new treatment option for benign prostatic hyperplasia. We present a case of radiation-induced dermitis in a 63-year-old patient after a technically successful PAE, due to high radiation exposure (KAP: 8,023,949 mGy cm 2 ) and long fluoroscopy time (72 min). Anatomical and technical aspects are discussed, as well as recommendations to decrease radiation exposure in these procedures

[Miks uurib politsei Ottise ja ehitusfirma Facio vahelist tüli?] / Tarmo Vahter

Index Scriptorium Estoniae

Vahter, Tarmo, 1970-

2006-01-01

Seoses koolitüdruku Veronika Dari tapmisega, kus tegelikuks sihtmärgiks oli Riigi Kinnisvara juht Tiit Ottis, tunneb politsei huvi kolme riigi poolt tellitud ehitustöö vastu. Need on keskkriminaalpolitsei peakorteri ning Tallinna Pae ja Mustamäe gümnaasiumi renoveerimine. Uurimise käigust. Vt. samas: Katkeid Riigi Kinnisvara ja Facio Ehituse juhtide kirjavahetusest Pae ja Mustamäe gümnaasiumide remondi teemal. Tiit Ottis: "Mehed, te rikastute alusetult!"

Radiodermitis After Prostatic Artery Embolization: Case Report and Review of the Literature

Energy Technology Data Exchange (ETDEWEB)

Laborda, Alicia, E-mail: alaborda@unizar.es [Universidad de Zaragoza, Group of Research in Minimally Invasive Techniques (GITMI), Facultad de Veterinaria (Spain); Assis, Andre Moreira De, E-mail: andre.maa@gmail.com [University of Sao Paulo Medical School, Interventional Radiology and Endovascular Surgery Department, Radiology Institute (Brazil); Ioakeim, Ignatios, E-mail: ignacio.ioakim@hotmail.es; Sánchez-Ballestín, María, E-mail: mirisanba@gmail.com [Universidad de Zaragoza, Group of Research in Minimally Invasive Techniques (GITMI), Facultad de Veterinaria (Spain); Carnevale, Francisco Cesar, E-mail: fcarnevale@uol.com.br [University of Sao Paulo Medical School, Interventional Radiology and Endovascular Surgery Department, Radiology Institute (Brazil); Gregorio, Miguel Angel De, E-mail: mgregori@unizar.es [Universidad de Zaragoza, Group of Research in Minimally Invasive Techniques (GITMI), Facultad de Veterinaria (Spain)

2015-06-15

Prostate artery embolization (PAE) is a technically demanding new treatment option for benign prostatic hyperplasia. We present a case of radiation-induced dermitis in a 63-year-old patient after a technically successful PAE, due to high radiation exposure (KAP: 8,023,949 mGy cm{sup 2}) and long fluoroscopy time (72 min). Anatomical and technical aspects are discussed, as well as recommendations to decrease radiation exposure in these procedures.

Item response theory analysis to evaluate reliability and minimal clinically important change of the Roland-Morris Disability Questionnaire in patients with severe disability due to back pain from vertebral compression fractures.

Science.gov (United States)

Lee, Minji K; Yost, Kathleen J; McDonald, Jennifer S; Dougherty, Ryne W; Vine, Roanna L; Kallmes, David F

2017-06-01

The majority of validation done on the Roland-Morris Disability Questionnaire (RMDQ) has been in patients with mild or moderate disability. There is paucity of research focusing on the psychometric quality of the RMDQ in patients with severe disability. To evaluate the psychometric quality of the RMDQ in patients with severe disability. Observational clinical study. The sample consisted of 214 patients with painful vertebral compression fractures who underwent vertebroplasty or kyphoplasty. The 23-item version of the RMDQ was completed at two time points: baseline and 30-day postintervention follow-up. With the two-parameter logistic unidimensional item response theory (IRT) analyses, we derived the range of scores that produced reliable measurement and investigated the minimal clinically important difference (MCID). Scores for 214 (100%) patients at baseline and 108 (50%) patients at follow-up did not meet the reliability criterion of 0.90 or higher, with the majority of patients having disability due to back pain that was too severe to be reliably measured by the RMDQ. Depending on methodology, MCID estimates ranged from 2 to 8 points and the proportion of patients classified as having experienced meaningful improvement ranged from 26% to 68%. A greater change in score was needed at the extreme ends of the score scale to be classified as having achieved MCID using IRT methods. Replacing items measuring moderate disability with items measuring severe disability could yield a version of the RMDQ that better targets patients with severe disability due to back pain. Improved precision in measuring disability would be valuable to clinicians who treat patients with greater functional impairments. Caution is needed when choosing criteria for interpreting meaningful change using the RMDQ. Copyright © 2017 Elsevier Inc. All rights reserved.

Attitudes of students of Jan Grodek State High Vocational School In Sanok towards organ donation

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Diana Lisowska

2017-08-01

Full Text Available Introduction. Transplantology is at a stage of its dynamic development. Despite legal regulations and social campaigns promoting the idea of transplantology, organ donors are missing in Poland. Most Poles are in favor of transplantation, but consenting to transplantation has a number of determinants including sociodemographic, cultural and personal ones. Their cognition allows us to take actions as regards promoting the idea of transplantology and changing the attitudes towards pro-transplantation. Aim of the study. Determination of student attitudes towards organ donation. Materials and methods. The study was conducted in 2017 and covered 355 students of Jan Grodek State High Vocational School in Sanok. Diagnostic survey method and survey technique were used. The research questionnaire was composed of 41 questions. Statistical significance level was assumed to be p <0.05. V-Kramer and Chi squares were used. Results. Most students, especially in medical fields, were supporters of organ transplants, both from living and dead donors. More than half of the respondents in case of a cerebral death would have agreed to donate their organs for transplant. More than half of the students expressed their donation for relatives, and over one quarter of them for the stramgers. More often than not, women declared this. More than half of the respondents would never have been financially financially guided donors, and one in five students strongly opposed to such a practice. Conclusions. Most respondents positively consider their presence in a situation where donor organs are required, both in the face of death and transplantation of a part of their body during the lifetime of relatives or even unrelated recipients. Attitudes of students towards organ donation were altruistic. The students were opposed to financial donations. Attitudes of students were different as regards: gender, place of residence and profile of studies.

Knowledge of cervical cancer risk factors among students at the Jan Kochanowski University in Kielce

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Piotr Lewitowicz

2013-10-01

Full Text Available Introduction : Cervical cancer is the third most common malignant tumour in women. As far as we know today, the main cause of cervical cancer is human papilloma virus (HPV infection with high grade oncogenic HPV genotypes, as well as co-occurrence of other factors predisposing women to cervical cancer. According to the WHO, the factors include smoking, multiple sexual partners, low socioeconomic status, herpes simplex virus (HSV co-infection, human immunodeficiency virus infection, and antioxidant and vitamin insufficiency in the diet. Aim of the research : To assess the knowledge of cervical cancer among young women. Material and methods: The survey was carried out in 2010–2012 in a group of 149 female students at the age of 20 ±1 at the Jan Kochanowski Memorial University, Kielce prior to gynaecology, pathology and oncology classes. The questionnaire survey included closed multiple choice questions. The statistical analyais was conducted by means of PQStat ver. 1.4.4 software using ANOVA and Fisher tests. Results and conclusions : The obtained results show that the 94% of the surveyed people are familiar with the impact of HPV infection, but knowledge of accessory risk factors of cervical cancer is at low level. The study revealed that smoking is regarded as another risk factor by 13% of the surveyed people, HSV infection by 9%, multiple sex partners by 21%, and low hygiene level by 25%. Our examination revealed differences regarding the knowledge and available information sources by the respondents’ place of residence. Knowledge level of cervical cancer development depends on the place of residence and reaches the highest level in towns with over 20,000 inhabitants. The main source of information on cervical cancer risk factors is Internet and peer opinions.

Brno: genius loci. 47. mezinárodní hudebněvědné kolokvium, konané při Mezinárodním festivalu Janáček Brno 2012, Brno, 19.-21. listopadu 2012

Czech Academy of Sciences Publication Activity Database

Bajgarová, Jitka

2013-01-01

Roč. 50, č. 1-2 (2013), s. 190-192 ISSN 0018-7003. [Brno: genius loci. 47. mezinárodní hudebněvědné kolokvium, konané při Mezinárodním festival u Janáček Brno 2012. Brno, 19.11.2012-21.11.2012] Institutional support: RVO:68378076 Keywords : musicological conference * Brno * genius loci Subject RIV: AL - Art, Architecture, Cultural Heritage

Taju vormiv arhitektuur / Eva Castro, Holger Kehne ; interv. Inga Raukas

Index Scriptorium Estoniae

Castro, Eva

2002-01-01

Londoni arhitektuuribüroo Plasma Studio arhitektid Eva Castro (s. 1969 Argentiinas) ja Holger Kehne (s. 1970 Saksamaal) räägivad oma tööst ja arhitektuurist. Loetletud büroo tähtsamad arhitektuuriauhinnad ja projektid. Osalesid 5. Põhja- ja Baltimaade arhitektuuritriennaalil

Barcelona A ja B = Barcelona A and B / Inga Raukas

Index Scriptorium Estoniae

Raukas, Inga, 1967-

2006-01-01

Barcelona arendamisest. Herzog ja de Meuroni büroos kavandatud Foorumi näitusekeskuses 2006. a. märtsist juuni alguseni avatud näitusest "Barcelona in Progress", mis püüab haarata eduloo ajalugu ja tulevikku. Bibliograafia lk. 71

Cytotoxicity of VEGF121/rGel on vascular endothelial cells resulting in inhibition of angiogenesis is mediated via VEGFR-2

Directory of Open Access Journals (Sweden)

Hittelman Walter N

2011-08-01

Full Text Available Abstract Background The fusion protein VEGF121/rGel composed of the growth factor VEGF121 and the plant toxin gelonin targets the tumor neovasculature and exerts impressive anti-vascular effects. We have previously shown that VEGF121/rGel is cytotoxic to endothelial cells overexpressing VEGFR-2 but not to endothelial cells overexpressing VEGFR-1. In this study, we examined the basis for the specific toxicity of this construct and assessed its intracellular effects in vitro and in vivo. Methods We investigated the binding, cytotoxicity and internalization profile of VEGF121/rGel on endothelial cells expressing VEGFR-1 or VEGFR-2, identified its effects on angiogenesis models in vitro and ex vivo, and explored its intracellular effects on a number of molecular pathways using microarray analysis. Results Incubation of PAE/VEGFR-2 and PAE/VEGFR-1 cells with 125I-VEGF121/rGel demonstrated binding specificity that was competed with unlabeled VEGF121/rGel but not with unlabeled gelonin. Assessment of the effect of VEGF121/rGel on blocking tube formation in vitro revealed a 100-fold difference in IC50 levels between PAE/VEGFR-2 (1 nM and PAE/VEGFR-1 (100 nM cells. VEGF121/rGel entered PAE/VEGFR-2 cells within one hour of treatment but was not detected in PAE/VEGFR-1 cells up to 24 hours after treatment. In vascularization studies using chicken chorioallantoic membranes, 1 nM VEGF121/rGel completely inhibited bFGF-stimulated neovascular growth. The cytotoxic effects of VEGF121/rGel were not apoptotic since treated cells were TUNEL-negative with no evidence of PARP cleavage or alteration in the protein levels of select apoptotic markers. Microarray analysis of VEGF121/rGel-treated HUVECs revealed the upregulation of a unique "fingerprint" profile of 22 genes that control cell adhesion, apoptosis, transcription regulation, chemotaxis, and inflammatory response. Conclusions Taken together, these data confirm the selectivity of VEGF121/rGel for VEGFR-2

The Relationship between Teacher Support and Students' Academic Emotions: A Meta-Analysis

Directory of Open Access Journals (Sweden)

Hao Lei

2018-01-01

Full Text Available This meta-analysis examines the association between teacher support and students' academic emotions [both positive academic emotions (PAEs and negative academic emotions (NAEs] and explores how student characteristics moderate these relationships. We identified 65 primary studies with 58,368 students. The results provided strong evidence linking teacher support and students' academic emotions. Furthermore, students' culture, age, and gender moderated these links. The correlation between teacher support and PAEs was stronger for Western European and American students than for East Asian students, while the correlation between teacher support and NAEs was stronger for East Asian students than for Western European and American students. Also, the correlation between teacher support and PAEs was strong among university students and weaker among middle school students, compared to other students. The correlation between teacher support and NAEs was stronger for middle school students and for female students, compared to other students.

Studies of Oxidation of the Cu(100) Surface Using Low Energy Positrons

International Nuclear Information System (INIS)

Fazleev, N. G.; Maddox, W. B.; Nadesalingam, M.; Rajeshwar, K.; Weiss, A. H.

2009-01-01

Changes in the surface of an oxidized Cu(100) single crystal resulting from vacuum annealing have been investigated using positron annihilation induced Auger electron spectroscopy (PAES). PAES measurements show a large increase in the intensity of the positron annihilation induced Cu M 2,3 VV Auger peak as the sample is subjected to a series of isochronal anneals in vacuum up to annealing temperature 300 deg. C. The intensity then decreases monotonically as the annealing temperature is increased to ∼600 deg. C. Experimental PAES results are analyzed by performing calculations of positron surface states and annihilation probabilities of surface-trapped positrons with relevant core electrons taking into account the charge redistribution at the surface, surface reconstructions, and electron-positron correlations effects. Possible explanation for the observed behavior of the intensity of positron annihilation induced Cu M 2,3 VV Auger peak with changes of the annealing temperature is proposed.