WorldWideScience

Sample records for p212121 space group

  1. A P212121 polymorph of (+-clusianone

    Directory of Open Access Journals (Sweden)

    Teng-Jin Khoo

    2013-12-01

    Full Text Available The title compound, C33H42O4 [systematic name: (1S,5S,7R-3-benzoyl-4-hydroxy-8,8-dimethyl-1,5,7-tris(3-methylbut-2-enylbicyclo[3.3.1]nona-3-ene-2,9-dione], has a central bicyclo[3.3.1]nonane-2,4,9-trione surrounded by tetraprenylated and benzoyl groups. The compound was recrystallized several times in methanol using both a slow evaporation method and with a crystal-seeding technique. This subsequently produced diffraction-quality crystals which crystallize in the orthorhombic space group P212121, in contrast to a previous report of a structure determination in the Pna21 space group [McCandlish et al. (1976. Acta Cryst. B32, 1793–1801]. The title compound has a melting point of 365–366 K, and a specific rotation [α]20 value of +51.94°. A strong intramolecular O—H...O hydrogen bond is noted. In the crystal, molecules are assembled in the ab plane by weak C—H...O interactions.

  2. Selenomethionine substitution of orotidine-5-monophosphate decarboxylase causes a change in crystal contacts and space group

    DEFF Research Database (Denmark)

    Poulsen, Jens-Christian Navarro; Harris, Pernille; Jensen, Kaj Frank

    2001-01-01

    with the inhibitor 1-(5'-phospho- -D-ribofuranosyl)barbituric acid crystallizes under similar conditions as the native enzyme. In contrast to the native enzyme, where the crystals belong to the orthorhombic space group P212121, the SeMet-substituted enzyme crystallizes in the monoclinic space group P21......-wavelength anomalous dispersion technique, both native and SeMet-substituted proteins have been produced and purified. During the production of SeMet ODCase, it was observed that SeMet was the only amino acid that it was necessary to add to the defined medium during expression. SeMet-substituted ODCase in complex...

  3. ORF Alignment: NC_000913 [GENIUS II[Archive

    Lifescience Database Archive (English)

    Full Text Available 2|D Chain D, ... E. Coli Ribokinase Complexed With Ribose And Adp, Solved ... In Space Group P...d Adp, Solved In ... Space Group P212121 pdb|1RK2|B Chain B, E. Coli ... Ribokinase Complexed ...With Ribose And Adp, Solved In ... Space Group P212121 pdb|1RK2|A Chain A, E. Coli ... Ribokin...ase Complexed With Ribose And Adp, Solved In ... Space Group P212121 pdb|1

  4. ORF Alignment: NC_002695 [GENIUS II[Archive

    Lifescience Database Archive (English)

    Full Text Available 2|D Chain D, ... E. Coli Ribokinase Complexed With Ribose And Adp, Solved ... In Space Group P...d Adp, Solved In ... Space Group P212121 pdb|1RK2|B Chain B, E. Coli ... Ribokinase Complexed ...With Ribose And Adp, Solved In ... Space Group P212121 pdb|1RK2|A Chain A, E. Coli ... Ribokin...ase Complexed With Ribose And Adp, Solved In ... Space Group P212121 pdb|1

  5. ORF Alignment: NC_002655 [GENIUS II[Archive

    Lifescience Database Archive (English)

    Full Text Available 2|D Chain D, ... E. Coli Ribokinase Complexed With Ribose And Adp, Solved ... In Space Group P...d Adp, Solved In ... Space Group P212121 pdb|1RK2|B Chain B, E. Coli ... Ribokinase Complexed ...With Ribose And Adp, Solved In ... Space Group P212121 pdb|1RK2|A Chain A, E. Coli ... Ribokin...ase Complexed With Ribose And Adp, Solved In ... Space Group P212121 pdb|1

  6. Mapping Spaces, Centralizers, and p-Local Finite Groups of Lie Type

    DEFF Research Database (Denmark)

    Laude, Isabelle

    We study the space of maps from the classifying space of a finite p-group to theBorel construction of a finite group of Lie type G in characteristic p acting on itsbuilding. The first main result is a description of the homology with Fp-coefficients,showing that the mapping space, up to p...... between a finite p-group and theuncompleted classifying space of the p-local finite group coming from a finite groupof Lie type in characteristic p, providing some of the first results in this uncompletedsetting.......-completion, is a disjoint union indexedover the group homomorphism up to conjugation of classifying spaces of centralizersof p-subgroups in the underlying group G. We complement this description bydetermining the actual homotopy groups of the mapping space. These resultstranslate to descriptions of the space of maps...

  7. Expression, purification, crystallization and preliminary X-ray analysis of conjugated polyketone reductase C2 (CPR-C2) from Candida parapsilosis IFO 0708

    OpenAIRE

    Yamamura, Akihiro; Maruoka, Shintaro; Ohtsuka, Jun; Miyakawa, Takuya; Nagata, Koji; Kataoka, Michihiko; Kitamura, Nahoko; Shimizu, Sakayu; Tanokura, Masaru

    2009-01-01

    Conjugated polyketone reductase C2 from C. parapsilosis IFO 0708 was expressed, purified and crystallized by the sitting-drop vapour-diffusion method. The crystal belonged to space group P212121 and diffracted X-rays to 1.7 Å resolution.

  8. String cohomology groups of complex projective spaces

    DEFF Research Database (Denmark)

    Ottosen, Iver; Bökstedt, Marcel

    2007-01-01

    Let X be a space and write LX for its free loop space equipped with the action of the circle group T given by dilation. The equivariant cohomology H*(LXhT;Z/p) is a module over H*(BT;Z/p). We give a computation of this module when X=CPr for any positive integer r and any prime number p. The compu......Let X be a space and write LX for its free loop space equipped with the action of the circle group T given by dilation. The equivariant cohomology H*(LXhT;Z/p) is a module over H*(BT;Z/p). We give a computation of this module when X=CPr for any positive integer r and any prime number p...

  9. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Compound 1 crystallizes in the orthorhombic chiral P212121 space group with = 4, = 10.21(2), = 11.574(3), = 25.364(9). Each copper shows square pyramidal geometry with O2NCl2 coordination and the Cu2Cl2 core geometry adopts a butterfly shape. Crystals of 1 were further characterized by elemental analysis, ...

  10. Crystal structures and theoretical studies of polyphosphate LiZnP3O9 for nonlinear optical applications

    Science.gov (United States)

    Xie, Zhiqing; Su, Xin; Ding, Hanqin; Li, Hongyi

    2018-06-01

    Nonlinear optical materials have attracted worldwide attention owing to their wide range of applications, specially in the laser field. Phosphates with noncentrosymmetric structures are potential candidates for novel ultraviolet (UV)-NLO materials, because they usually display short UV cut-off edges. In this work, a polyphosphate, the LiZnP3O9 polyphosphate crystals were grown through spontaneous crystallization from high-temperature melts. It crystallizes in the orthorhombic space group P212121 with unit cell parameters a = 8.330(3) Å, b = 8.520(3) Å, c = 8.635(3) Å, and Z = 4. In the structure, all the P atoms are coordinated by four oxygen atoms forming the [PO4] tetrahedra and further connected to generate a zig-zag [PO3]∞ anionic framework. Thermal analysis, IR spectroscopy, UV-vis-NIR diffuse reflectance spectrum and powder second harmonic generation measurements are performed. In addition, the first-principles calculation was employed for better understanding the structure-property relationships of LiZnP3O9.

  11. Automorphism group of nonabelian groups of order p{sup 3}

    Energy Technology Data Exchange (ETDEWEB)

    Sarmin, Nor Haniza [Department of Mathematical Sciences, Faculty of Science, Universiti Teknologi Malaysia, 81310 UTM Johor Bahru (Malaysia); Barakat, Yasamin [Department of Mathematical Sciences, Faculty of Science, Universiti Teknologi Malaysia, 81310 UTM Johor Bahru, Malaysia and Islamic Azad University-Ahvaz Branch, Ahvaz (Iran, Islamic Republic of)

    2014-06-19

    Let G be a nonabelian group of order p{sup 3}, where p is a prime number. Then G is a two generated group that its commutator, centre and Frattini subgroup coincide and are of order p. Hence, the quotient group of G over its centre and also Frattini quotient group of G, both are of order p{sup 2}. However, the first mentioned quotient is isomorphic to the inner group of G, which is a normal subgroup of automorphism group of G. Whereas, Frattini quotient group of G is an abelian elementary group that can be considered as a vector space of dimension two over Z{sub p}, the field of integers modulo p. In this paper, we consider to apply these properties of G to characterize the automorphism group of G.

  12. Simple derivation of magnetic space groups

    International Nuclear Information System (INIS)

    Bertaut, E.F.; CEA Centre d'Etudes Nucleaires de Grenoble, 38

    1975-01-01

    The magnetic translation lattices can be described by invariant wave vectors k. Advantages of the wave vector notation over the notations used by Belov et al. and Opechowski et al. are pointed out. In a one-dimensional real representation a space group element (α/tau(1)) has either the character +1 (symmetry element) or -1 (antisymmetry element). Thus the square of any space group operation must have the character +1 in a one-dimensional real representation. This simple ''square criterion'' is used to limit the admissible k-vectors and to derive the family of magnetic space groups, i.e. the set of all possible magnetic space groups, belonging to the same crystallographic space group. In the discussion some useful side results are obtained. Not only the real one-dimensional representations of point groups are connected to real one-dimensional representations of space groups, but a direct connection is shown to exist between one-dimensional complex representations of the point groups 3, 4 and 6 and one-dimensional real representations, belonging to P[001/2]=Psub(2c)(Psub(c))-lattices with screw axes 3 1 , 3 2 , 4 2 , 6 2 and 6 4 . Rules are derived for finding the Belov symbol when the Opechowski-Guccione symbol of the magnetic space group is known and this opportunity is used for correcting errors in the Opechowski-Guccione tables [fr

  13. Space-Time Crystal and Space-Time Group.

    Science.gov (United States)

    Xu, Shenglong; Wu, Congjun

    2018-03-02

    Crystal structures and the Bloch theorem play a fundamental role in condensed matter physics. We extend the static crystal to the dynamic "space-time" crystal characterized by the general intertwined space-time periodicities in D+1 dimensions, which include both the static crystal and the Floquet crystal as special cases. A new group structure dubbed a "space-time" group is constructed to describe the discrete symmetries of a space-time crystal. Compared to space and magnetic groups, the space-time group is augmented by "time-screw" rotations and "time-glide" reflections involving fractional translations along the time direction. A complete classification of the 13 space-time groups in one-plus-one dimensions (1+1D) is performed. The Kramers-type degeneracy can arise from the glide time-reversal symmetry without the half-integer spinor structure, which constrains the winding number patterns of spectral dispersions. In 2+1D, nonsymmorphic space-time symmetries enforce spectral degeneracies, leading to protected Floquet semimetal states. We provide a general framework for further studying topological properties of the (D+1)-dimensional space-time crystal.

  14. Disintegration of positive isometric group representations on L^p-spaces

    NARCIS (Netherlands)

    Jeu, de M.F.E.; Rozendaal, J.

    2017-01-01

    Let G be a Polish locally compact group acting on a Polish space X" role="presentation">X with a G-invariant probability measure μ" role="presentation">μ. We factorize the integral with respect to μ" role="presentation">μ in terms of the integrals with respect to the ergodic measures on X, and show

  15. Twistor space, Minkowski space and the conformal group

    International Nuclear Information System (INIS)

    Broek, P.M. van den

    1983-01-01

    It is shown that the conformal group of compactified Minkowski space is isomorphic to a group of rays of semilinear transformations of twistor space. The action of the conformal group on twistor space is given by an explicit realisation of this isomorphism. In this way we determine the transformation of twistor space under space inversion and time inversion. (orig.)

  16. Methyl (Sp-2-(diphenylphosphinoferrocene-1-carboxylate

    Directory of Open Access Journals (Sweden)

    Petr Štěpnička

    2009-10-01

    Full Text Available The title compound, [Fe(C5H5(C19H16O2P], obtained serendipitously during recrystallization of 1-hydroxybenzotriazolyl (Sp-2-(diphenylphosphinoferrocene-1-carboxylate from methanol, crystallizes in the chiral space group P212121. Its crystal structure not only confirms the anticipated absolute configuration but also establishes a rather regular geometry for the ferrocene unit, devoid of any significant deformation due to the attached substituents. In the crystal, symmetry-related molecules are linked via weak C—H...O interactions.

  17. Twistor space, Minkowski space and the conformal group

    NARCIS (Netherlands)

    van den Broek, P.M.

    1983-01-01

    It is shown that the conformal group of compactified Minkowski space is isomorphic to a group of rays of semilinear transformations of twistor space. The action of the conformal group on twistor space is given by an explicit realisation of this isomorphism. In this way we determine the

  18. X-ray analysis of 2-aniline benzo(2,3-)

    Indian Academy of Sciences (India)

    dione has been determined by X-ray crystallographic techniques. This compound crystallizes in the orthorhombic space group 212121 with unit cell parameters: = 5.467(1), = 10.657(3), = 19.602(6) Å; = 1142.01(5) Å3, = 4.

  19. Trimesic acid dimethyl sulfoxide solvate: space group revision

    Directory of Open Access Journals (Sweden)

    Sylvain Bernès

    2008-07-01

    Full Text Available The structure of the title solvate, C9H6O6·C2H6OS, was determined 30 years ago [Herbstein, Kapon & Wasserman (1978. Acta Cryst. B34, 1613–1617], with data collected at room temperature, and refined in the space group P21. The present redetermination, based on high-resolution diffraction data, shows that the actual space group is more likely to be P21/m. The crystal structure contains layers of trimesic acid molecules lying on mirror planes. A mirror plane also passes through the S and O atoms of the solvent molecule. The molecules in each layer are interconnected through strong O—H...O hydrogen bonds, forming a two-dimensional supramolecular network within each layer. The donor groups are the hydroxyls of the trimesic acid molecules, while the acceptors are the carbonyl or the sulfoxide O atoms.

  20. 3,4-Dibromo-2,2,5,5-tetraphenyl-2,5-dihydrofuran

    Directory of Open Access Journals (Sweden)

    Nadine Seidel

    2018-04-01

    Full Text Available The crystal structure of the title compound, C28H20Br2O, was solved in the orthorhombic space group P212121 with one molecule in the asymmetric unit. The phenyl rings are nearly planar and inclined at angles of 67.7 (1, 68.8 (1, 79.3 (1 and 62.3 (1° to the plane of the 2,5-dihydrofuran ring. The crystal structure features C—H...π and Br...Br interactions, which connect the molecules to a three-dimensional supramolecular network.

  1. Hydrogen-bonded co-crystal structure of benzoic acid and zwitterionic l-proline

    Directory of Open Access Journals (Sweden)

    Aaron M. Chesna

    2017-03-01

    Full Text Available The title compound [systematic name: benzoic acid–pyrrolidin-1-ium-2-carboxylate (1/1], C7H6O2·C5H9NO2, is an example of the application of non-centrosymmetric co-crystallization for the growth of a crystal containing a typically centrosymmetric component in a chiral space group. It co-crystallizes in the space group P212121 and contains benzoic acid and l-proline in equal proportions. The crystal structure exhibits chains of l-proline zwitterions capped by benzoic acid molecules which form a C(5[R33(11] hydrogen-bonded network along [100]. The crystal structure is examined and compared to that of a similar co-crystal containing l-proline zwitterions and 4-aminobenzoic acid.

  2. Space groups for solid state scientists

    CERN Document Server

    Glazer, Michael; Glazer, Alexander N

    2014-01-01

    This Second Edition provides solid state scientists, who are not necessarily experts in crystallography, with an understandable and comprehensive guide to the new International Tables for Crystallography. The basic ideas of symmetry, lattices, point groups, and space groups are explained in a clear and detailed manner. Notation is introduced in a step-by-step way so that the reader is supplied with the tools necessary to derive and apply space group information. Of particular interest in this second edition are the discussions of space groups application to such timely topics as high-te

  3. Johnson Space Center's Risk and Reliability Analysis Group 2008 Annual Report

    Science.gov (United States)

    Valentine, Mark; Boyer, Roger; Cross, Bob; Hamlin, Teri; Roelant, Henk; Stewart, Mike; Bigler, Mark; Winter, Scott; Reistle, Bruce; Heydorn,Dick

    2009-01-01

    The Johnson Space Center (JSC) Safety & Mission Assurance (S&MA) Directorate s Risk and Reliability Analysis Group provides both mathematical and engineering analysis expertise in the areas of Probabilistic Risk Assessment (PRA), Reliability and Maintainability (R&M) analysis, and data collection and analysis. The fundamental goal of this group is to provide National Aeronautics and Space Administration (NASA) decisionmakers with the necessary information to make informed decisions when evaluating personnel, flight hardware, and public safety concerns associated with current operating systems as well as with any future systems. The Analysis Group includes a staff of statistical and reliability experts with valuable backgrounds in the statistical, reliability, and engineering fields. This group includes JSC S&MA Analysis Branch personnel as well as S&MA support services contractors, such as Science Applications International Corporation (SAIC) and SoHaR. The Analysis Group s experience base includes nuclear power (both commercial and navy), manufacturing, Department of Defense, chemical, and shipping industries, as well as significant aerospace experience specifically in the Shuttle, International Space Station (ISS), and Constellation Programs. The Analysis Group partners with project and program offices, other NASA centers, NASA contractors, and universities to provide additional resources or information to the group when performing various analysis tasks. The JSC S&MA Analysis Group is recognized as a leader in risk and reliability analysis within the NASA community. Therefore, the Analysis Group is in high demand to help the Space Shuttle Program (SSP) continue to fly safely, assist in designing the next generation spacecraft for the Constellation Program (CxP), and promote advanced analytical techniques. The Analysis Section s tasks include teaching classes and instituting personnel qualification processes to enhance the professional abilities of our analysts

  4. Crystal structures of the all-cysteinyl-coordinated D14C variant of Pyrococcus furiosus ferredoxin: [4Fe–4S] ↔ [3Fe–4S] cluster conversion

    DEFF Research Database (Denmark)

    Løvgreen, Monika Nøhr; Martic, Maja; Windahl, Michael S.

    2011-01-01

    The structure of the all-cysteinyl-coordinated D14C variant of [4Fe–4S] ferredoxin from the hyperthermophilic archaeon Pyrococcus furiosus has been determined to 1.7 Å resolution from a crystal belonging to space group C2221 with two types of molecules, A and B, in the asymmetric unit. A and B...... molecules have different crystal packing and intramolecular disulfide bond conformation. The crystal packing reveals a β-sheet interaction between A molecules in adjacent asymmetric units, whereas B molecules are packed as monomers in a less rigid position next to the A–A extended β-sheet dimers...... and purification are carried out at pH 5.8, only the monomer is obtained. The crystal structure of D14C [3Fe–4S] P. furiosus ferredoxin monomer was determined to 2.8 Å resolution from a crystal belonging to space group P212121 with two molecules in the asymmetric unit. The molecules resemble molecule A of D14C [4...

  5. NCBI nr-aa BLAST: CBRC-MLUC-01-0889 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available neurons protein 2 pdb|3HAJ|A Chain A, Crystal Structure Of Human Pacsin2 F-Bar Domain (P212121 Lattice) pdb...|3HAJ|B Chain B, Crystal Structure Of Human Pacsin2 F-Bar Domain (P212121 Lattice

  6. NCBI nr-aa BLAST: CBRC-OPRI-01-0218 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available neurons protein 2 pdb|3HAJ|A Chain A, Crystal Structure Of Human Pacsin2 F-Bar Domain (P212121 Lattice) pdb...|3HAJ|B Chain B, Crystal Structure Of Human Pacsin2 F-Bar Domain (P212121 Lattice

  7. NCBI nr-aa BLAST: CBRC-PHAM-01-1678 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available neurons protein 2 pdb|3HAJ|A Chain A, Crystal Structure Of Human Pacsin2 F-Bar Domain (P212121 Lattice) pdb...|3HAJ|B Chain B, Crystal Structure Of Human Pacsin2 F-Bar Domain (P212121 Lattice

  8. The Lp Spectrum of Locally Symmetric Spaces with Small Fundamental Group

    International Nuclear Information System (INIS)

    Weber, Andreas

    2009-01-01

    We determine the L p spectrum of the Laplace-Beltrami operator on certain complete locally symmetric spaces M whose universal covering X is a symmetric space of non-compact type with rank one. More precisely, we show that the L p spectra of M and X coincide if the fundamental group of M is small and if the injectivity radius of M is bounded away from zero. In the L 2 case, the restriction on the injectivity radius is not needed

  9. Crystal structure of papain-E64-c complex. Binding diversity of E64-c to papain S2 and S3 subsites.

    OpenAIRE

    Kim, M J; Yamamoto, D; Matsumoto, K; Inoue, M; Ishida, T; Mizuno, H; Sumiya, S; Kitamura, K

    1992-01-01

    In order to investigate the binding mode of E64-c (a synthetic cysteine proteinase inhibitor) to papain at the atomic level, the crystal structure of the complex was analysed by X-ray diffraction at 1.9 A (1 A is expressed in SI units as 0.1 nm) resolution. The crystal has a space group P2(1)2(1)2(1) with a = 43.37, b = 102.34 and c = 49.95 A. A total of 21,135 observed reflections were collected from the same crystal, and 14811 unique reflections of up to 1.9 A resolution [Fo > 3 sigma(Fo)] ...

  10. Mapping spaces and automorphism groups of toric noncommutative spaces

    Science.gov (United States)

    Barnes, Gwendolyn E.; Schenkel, Alexander; Szabo, Richard J.

    2017-09-01

    We develop a sheaf theory approach to toric noncommutative geometry which allows us to formalize the concept of mapping spaces between two toric noncommutative spaces. As an application, we study the `internalized' automorphism group of a toric noncommutative space and show that its Lie algebra has an elementary description in terms of braided derivations.

  11. Structure of a new crystal form of human Hsp70 ATPase domain.

    Science.gov (United States)

    Osipiuk, J; Walsh, M A; Freeman, B C; Morimoto, R I; Joachimiak, A

    1999-05-01

    Hsp70 proteins are highly conserved proteins induced by heat shock and other stress conditions. An ATP-binding domain of human Hsp70 protein has been crystallized in two major morphological forms at pH 7.0 in the presence of PEG 8000 and CaCl2. Both crystal forms belong to the orthorhombic space group P212121, but show no resemblance in unit-cell parameters. Analysis of the crystal structures for both forms shows a 1-2 A shift of one of the subdomains of the protein. This conformational change could reflect a 'natural' flexibility of the protein which might be relevant to ATP binding and may facilitate the interaction of other proteins with Hsp70 protein.

  12. Purification, crystallization and preliminary crystallographic analysis of the adhesion domain of Epf from Streptococcus pyogenes.

    Science.gov (United States)

    Linke, Christian; Siemens, Nikolai; Middleditch, Martin J; Kreikemeyer, Bernd; Baker, Edward N

    2012-07-01

    The extracellular protein Epf from Streptococcus pyogenes is important for streptococcal adhesion to human epithelial cells. However, Epf has no sequence identity to any protein of known structure or function. Thus, several predicted domains of the 205 kDa protein Epf were cloned separately and expressed in Escherichia coli. The N-terminal domain of Epf was crystallized in space groups P2(1) and P2(1)2(1)2(1) in the presence of the protease chymotrypsin. Mass spectrometry showed that the species crystallized corresponded to a fragment comprising residues 52-357 of Epf. Complete data sets were collected to 2.0 and 1.6 Å resolution, respectively, at the Australian Synchrotron.

  13. A comparative study on the crystal structure of bicycle analogues to the natural phytotoxin helminthosporins

    Science.gov (United States)

    Barbosa, Luiz Cláudio de Almeida; Teixeira, Robson Ricardo; Nogueira, Leonardo Brandão; Maltha, Celia Regina Alvares; Doriguetto, Antônio Carlos; Martins, Felipe Terra

    2016-02-01

    Herein we described structural insights of a series of analogues to helminthosporin phytotoxins. The key reaction used to prepare the compounds corresponded to the [3 + 4] cycloaddition between the oxyallyl cation generated from 2,4-dibromopentan-3-one and different furans. Their structures were confirmed upon IR, NMR and X-ray diffraction analyses. While bicycles 7, 8 and 9 crystallize in the centrosymmetric monoclinic space group P21/c, compound 10 was solved in the noncentrosymmetric orthorhombic space group P212121. The solid materials obtained were shown to be racemic crystals (7, 8, 9) or racemic conglomerate (10). In all compounds, there is formation of a bicycle featured by fused tetrahydropyranone and 2,5-dihydrofuran rings. They adopt chair and envelope conformations, respectively. Crystal packing of all compounds is stabilized through C-H•••O contacts. Conformational aspects as well as similarities and differences among the crystal structures of the synthesized analogues are discussed.

  14. Synthesis and characterization of strontium carboxylates at room temperature and at high temperature in autoclave vessels

    DEFF Research Database (Denmark)

    Christgau, Stephan; Ståhl, Kenny; Andersen, Jens Enevold Thaulov

    2006-01-01

    A novel method was developed for synthesis of strontium coordination compounds in high yields. The synthesis proceeded along three pathways that provided strontium salts in high purity and high yields, close to 100%, as confirmed by flame atomic absorption spectroscopy (FAAS) and powder x......-ray crystallography. Optimum conditions were found at T = 120-1400C, a base-to-acid ratio of 1.2 and 15 min. of reaction-time in an autoclave vessel. Large crystals were readily obtained within a time period of hours. The crystal structures of strontium D-glutamate hexahydrate (I) and strontium di-(hydrogen L......-glutamate) pentahydrate (II) were confirmed by X-ray powder diffraction at 295 K and Rietveld refinements (I: Space group P212121, Z=4, a=7.3519(2), b=8.7616(2), c=20.2627(5) Å, and II: Space group P21, Z=2, a=8.7243(1), b=7.2635(1), c=14.6840(2) Å, β=100.5414(7) °). Synthesis at room temperature provided four additional...

  15. Crystallization and preliminary X-ray analysis of recombinant Glomerella cingulata cutinase.

    Science.gov (United States)

    Nyon, Mun Peak; Rice, David W; Berrisford, John M; Huang, Huazhang; Moir, Arthur J G; Craven, C Jeremy; Nathan, Sheila; Mahadi, Nor Muhammad; Abu Bakar, Farah Diba

    2008-06-01

    Cutinase catalyzes the hydrolysis of water-soluble esters and long-chain triglycerides and belongs to the family of serine hydrolases. The enzyme is thought to represent an evolutionary link between the esterase and lipase families and has potential applications in a wide range of industrial hydrolytic processes, for which an understanding of the molecular basis of its substrate specificity is critical. Glomerella cingulata cutinase has been cloned and the protein has been overexpressed in Escherichia coli, purified and subsequently crystallized in a wide range of different crystal forms in the presence and absence of inhibitors. The best crystals are those of the apo cutinase, which diffract to beyond 1.6 A resolution and belong to space group P4(1)2(1)2 or P4(3)2(1)2. Crystals of cutinase with the inhibitors PETFP or E600 belong to space groups P2(1)2(1)2(1) and P2(1), respectively, and diffract to approximately 2.5 A resolution. All of the crystals are suitable for structural studies, which are currently ongoing.

  16. Quantum group gauge theory on quantum spaces

    International Nuclear Information System (INIS)

    Brzezinski, T.; Majid, S.

    1993-01-01

    We construct quantum group-valued canonical connections on quantum homogeneous spaces, including a q-deformed Dirac monopole on the quantum sphere of Podles quantum differential coming from the 3-D calculus of Woronowicz on SU q (2). The construction is presented within the setting of a general theory of quantum principal bundles with quantum group (Hopf algebra) fiber, associated quantum vector bundles and connection one-forms. Both the base space (spacetime) and the total space are non-commutative algebras (quantum spaces). (orig.)

  17. Redetermination and absolute configuration of atalaphylline

    Directory of Open Access Journals (Sweden)

    Hoong-Kun Fun

    2010-02-01

    Full Text Available The title acridone alkaloid [systematic name: 1,3,5-trihydroxy-2,4-bis(3-methylbut-2-enylacridin-9(10H-one], C23H25NO4, has previously been reported as crystallizing in the chiral orthorhombic space group P212121 [Chantrapromma et al. (2010. Acta Cryst. E66, o81–o82] but the absolute configuration could not be determined from data collected with Mo radiation. The absolute configuration has now been determined by refinement of the Flack parameter with data collected using Cu radiation. All features of the molecule and its crystal packing are similar to those previously described.

  18. Canadian space agency discipline working group for space dosimetry and radiation science

    International Nuclear Information System (INIS)

    Waker, Anthony; Waller, Edward; Lewis, Brent; Bennett, Leslie; Conroy, Thomas

    2008-01-01

    Full text: One of the great technical challenges in the human and robotic exploration of space is the deleterious effect of radiation on humans and physical systems. The magnitude of this challenge is broadly understood in terms of the sources of radiation, however, a great deal remains to be done in the development of instrumentation, suitable for the space environment, which can provide real-time monitoring of the complex radiation fields encountered in space and a quantitative measure of potential biological risk. In order to meet these research requirements collaboration is needed between experimental nuclear instrumentation scientists, theoretical scientists working on numerical modeling techniques and radiation biologists. Under the auspices of the Canadian Space Agency such a collaborative body has been established as one of a number of Discipline Working Groups. Members of the Space Dosimetry and Radiation Science working group form a collaborative network across Canada including universities, government laboratories and the industrial sector. Three central activities form the core of the Space Dosimetry and Radiation Science DWG. An instrument sub-group is engaged in the development of instruments capable of gamma ray, energetic charged particle and neutron dosimetry including the ability to provide dosimetric information in real-time. A second sub-group is focused on computer modeling of space radiation fields in order to assess the performance of conceptual designs of detectors and dosimeters or the impact of radiation on cellular and sub-cellular biological targets and a third sub-group is engaged in the study of the biological effects of space radiation and the potential of biomarkers as a method of assessing radiation impact on humans. Many working group members are active in more than one sub-group facilitating communication throughout the whole network. A summary progress-report will be given of the activities of the Discipline Working Group and the

  19. Sobolev Spaces on Locally Compact Abelian Groups: Compact Embeddings and Local Spaces

    Directory of Open Access Journals (Sweden)

    Przemysław Górka

    2014-01-01

    Full Text Available We continue our research on Sobolev spaces on locally compact abelian (LCA groups motivated by our work on equations with infinitely many derivatives of interest for string theory and cosmology. In this paper, we focus on compact embedding results and we prove an analog for LCA groups of the classical Rellich lemma and of the Rellich-Kondrachov compactness theorem. Furthermore, we introduce Sobolev spaces on subsets of LCA groups and study its main properties, including the existence of compact embeddings into Lp-spaces.

  20. The classification of p-compact groups for p odd

    DEFF Research Database (Denmark)

    Andersen, Kasper K. S.; Grodal, Jesper Kragh; Møller, Jesper Michael

    2008-01-01

    A p-compact group, as defined by Dwyer and Wilkerson, is a purely homotopically defined p-local analog of a compact Lie group. It has long been the hope, and later the conjecture, that these objects should have a classification similar to the classification of compact Lie groups. In this paper we...... groups are uniquely determined as p-compact groups by their Weyl groups seen as finite reflection groups over the p-adic integers. Our approach in fact gives a largely self-contained proof of the entire classification theorem for p odd....

  1. Noncommutative phase spaces on Aristotle group

    Directory of Open Access Journals (Sweden)

    Ancille Ngendakumana

    2012-03-01

    Full Text Available We realize noncommutative phase spaces as coadjoint orbits of extensions of the Aristotle group in a two dimensional space. Through these constructions the momenta of the phase spaces do not commute due to the presence of a naturally introduced magnetic eld. These cases correspond to the minimal coupling of the momentum with a magnetic potential.

  2. Retabulation of space group extinctions for electron diffraction

    International Nuclear Information System (INIS)

    Goodman, P.; Tanaka, M.

    1989-01-01

    The space group tables previously published by one of the authors and others are here presented in a revised and compacted form designed to make for compatability with existing tables for X-ray diffraction. 136 of the 230 space groups are subject to dynamic extinctions due to glide planes and screw axes, and the observables from these space groups in specific settings are tabulated. Tabs

  3. Group structure and group process for effective space station astronaut teams

    Science.gov (United States)

    Nicholas, J. M.; Kagan, R. S.

    1985-01-01

    Space Station crews will encounter new problems, many derived from the social interaction of groups working in space for extended durations. Solutions to these problems must focus on the structure of groups and the interaction of individuals. A model of intervention is proposed to address problems of interpersonal relationships and emotional stress, and improve the morale, cohesiveness, and productivity of astronaut teams.

  4. Student Facebook groups as a third space

    DEFF Research Database (Denmark)

    Aaen, Janus Holst; Dalsgaard, Christian

    2016-01-01

    -institutional, personal space of the Facebook network. The main study of the article examines six student-managed Facebook groups and provides an analysis of a total of 2247 posts and 12,217 comments. Furthermore, the study draws on group interviews with students from 17 Danish upper secondary schools and a survey......The paper examines educational potentials of Facebook groups that are created and managed by students without any involvement from teachers. The objective is to study student-managed Facebook groups as a ‘third space' between the institutional space of teacher-managed Facebook groups and the non...... answered by 932 students from 25 schools. Based on the survey and interviews, the paper concludes that Facebook is an important educational tool for students in Danish upper secondary schools to receive help on homework and assignments. Furthermore, on the basis of the analysis of Facebook groups...

  5. Hazy spaces, tangent spaces, manifolds and groups

    International Nuclear Information System (INIS)

    Dodson, C.T.J.

    1977-03-01

    The results on hazy spaces and the developments leading to hazy manifolds and groups are summarized. Proofs have appeared elsewhere so here examples are considered and some motivation for definitions and constructions in the theorems is analyzed. It is shown that quite simple ideas, intuitively acceptable, lead to remarkable similarity with the theory of differentiable manifolds. Hazy n manifolds have tangent bundles that are hazy 2n manifolds and there are hazy manifold structures for groups. Products and submanifolds are easily constructed and in particular the hazy n-sphere manifolds as submanifolds of the standard hazy manifold Zsup(n+1)

  6. (Benzyl isocyanide-κC1chlorido(2-chloro-3-dimethylamino-1-phenylprop-1-en-1-yl-κ2C1,Npalladium(II

    Directory of Open Access Journals (Sweden)

    Ana C. Mafud

    2013-01-01

    Full Text Available In the title compound, [Pd(C11H13ClNCl(C8H7N], which crystallized in the chiral space group P212121, the PdII atom is coordinated by two C atoms, a Csp2 atom of the 2-chloro-3-dimethylamino-1-phenylprop-1-en-1-yl ligand and a Csp atom from the benzyl isocyanide ligand, as well as an N atom of the ligand and a Cl atom, in a square-planar geometry. In the complex, there is a short C—H...Cl hydrogen bond and a C—H...π interaction. In the crystal, molecules are linked via C—H...Cl hydrogen bonds, forming chains along the a-axis direction.

  7. Crystal Structure of the N-Benzyloxycarbonyl-alanyl-phenylalanyl-methyl Ester: The Importance of the H-Bonding Pattern

    Directory of Open Access Journals (Sweden)

    Ignacio Alfonso

    2011-08-01

    Full Text Available Large crystals of the methyl ester of the N-a-benzyloxycarbonyl protected Ala-Phe dipeptide (Z-AF-OMe were obtained after the very slow evaporation of a solution of the corresponding carboxylic acid (Z-AF-OH in methanol containing an excess of HCl. The structure was confirmed by single crystal X-ray diffraction data. It crystallizes in the orthorhombic space group P212121 with unit cell dimensions a = 5.0655(6 Å, b = 8.4614(8 Å, c = 46.856(5 Å, V = 2008.3(4 Å3, Z = 4. In the crystal, the molecules form hydrogen bonded chains running along the a axis of the unit cell. Other secondary interactions are also discussed.

  8. Crystallization and preliminary X-ray analysis of native and selenomethionyl vinorine synthase from Rauvolfia serpentina.

    Science.gov (United States)

    Ma, Xueyan; Koepke, Juergen; Bayer, Anja; Fritzsch, Günter; Michel, Hartmut; Stöckigt, Joachim

    2005-06-01

    Vinorine synthase (VS) is a central enzyme of the biosynthesis of the antiarrhythmic drug ajmaline and is a member of the BAHD superfamily of acyltransferases. So far, no three-dimensional structure with significant sequence homology with VS is known. Crystals of VS and selenomethionyl-labelled VS from the medicinal plant Rauvolfia serpentina have been obtained by the hanging-drop technique at 305 K with ammonium sulfate and PEG 400 as precipitants. VS crystals diffract to 2.8 A and belong to space group P2(1)2(1)2(1), with unit-cell parameters a = 82.3, b = 89.6, c = 136.2 A. The selenomethionyl VS crystal was nearly isomorphous with the VS crystal.

  9. Crystals of DhaA mutants from Rhodococcus rhodochrous NCIMB 13064 diffracted to ultrahigh resolution: crystallization and preliminary diffraction analysis.

    Science.gov (United States)

    Stsiapanava, Alena; Koudelakova, Tana; Lapkouski, Mikalai; Pavlova, Martina; Damborsky, Jiri; Smatanova, Ivana Kuta

    2008-02-01

    The enzyme DhaA from Rhodococcus rhodochrous NCIMB 13064 belongs to the haloalkane dehalogenases, which catalyze the hydrolysis of haloalkanes to the corresponding alcohols. The haloalkane dehalogenase DhaA and its variants can be used to detoxify the industrial pollutant 1,2,3-trichloropropane (TCP). Three mutants named DhaA04, DhaA14 and DhaA15 were constructed in order to study the importance of tunnels connecting the buried active site with the surrounding solvent to the enzymatic activity. All protein mutants were crystallized using the sitting-drop vapour-diffusion method. The crystals of DhaA04 belonged to the orthorhombic space group P2(1)2(1)2(1), while the crystals of the other two mutants DhaA14 and DhaA15 belonged to the triclinic space group P1. Native data sets were collected for the DhaA04, DhaA14 and DhaA15 mutants at beamline X11 of EMBL, DESY, Hamburg to the high resolutions of 1.30, 0.95 and 1.15 A, respectively.

  10. The International Space Life Sciences Strategic Planning Working Group

    Science.gov (United States)

    White, Ronald J.; Rabin, Robert; Lujan, Barbara F.

    1993-01-01

    Throughout the 1980s, ESA and the space agencies of Canada, Germany, France, Japan, and the U.S. have pursued cooperative projects bilaterally and multilaterally to prepare for, and to respond to, opportunities in space life sciences research previously unapproachable in scale and sophistication. To cope effectively with likely future space research opportunities, broad, multilateral, coordinated strategic planning is required. Thus, life scientists from these agencies have allied to form the International Space Life Sciences Strategic Planning Working Group. This Group is formally organized under a charter that specifies the purpose of the Working Group as the development of an international strategic plan for the space life sciences, with periodic revisions as needed to keep the plan current. The plan will be policy-, not operations-oriented. The Working Group also may establish specific implementation teams to coordinate multilateral science policy in specific areas; such teams have been established for space station utilization, and for sharing of flight equipment.

  11. Automorphisms of p-compact groups and their root data

    DEFF Research Database (Denmark)

    Andersen, Kasper K. S.; Grodal, Jesper Kragh

    2008-01-01

    We construct a model for the space of automorphisms of a connected p–compact group in terms of the space of automorphisms of its maximal torus normalizer and its root datum. As a consequence we show that any homomorphism to the outer automorphism group of a p–compact group can be lifted to a group...... action, analogous to   a classical theorem of de Siebenthal for compact Lie groups. The model of this paper is used in a crucial way in our paper `The classification of 2-compact groups' [arXiv:math.AT/0611437], where we prove the conjectured classification of 2–compact groups and determine...... their automorphism spaces....

  12. NASA's Internal Space Weather Working Group

    Science.gov (United States)

    St. Cyr, O. C.; Guhathakurta, M.; Bell, H.; Niemeyer, L.; Allen, J.

    2011-01-01

    Measurements from many of NASA's scientific spacecraft are used routinely by space weather forecasters, both in the U.S. and internationally. ACE, SOHO (an ESA/NASA collaboration), STEREO, and SDO provide images and in situ measurements that are assimilated into models and cited in alerts and warnings. A number of years ago, the Space Weather laboratory was established at NASA-Goddard, along with the Community Coordinated Modeling Center. Within that organization, a space weather service center has begun issuing alerts for NASA's operational users. NASA's operational user community includes flight operations for human and robotic explorers; atmospheric drag concerns for low-Earth orbit; interplanetary navigation and communication; and the fleet of unmanned aerial vehicles, high altitude aircraft, and launch vehicles. Over the past three years we have identified internal stakeholders within NASA and formed a Working Group to better coordinate their expertise and their needs. In this presentation we will describe this activity and some of the challenges in forming a diverse working group.

  13. Quantum groups and quantum homogeneous spaces

    International Nuclear Information System (INIS)

    Kulish, P.P.

    1994-01-01

    The usefulness of the R-matrix formalism and the reflection equations is demonstrated on examples of the quantum group covariant algebras (quantum homogeneous spaces): quantum Minkowski space-time, quantum sphere and super-sphere. The irreducible representations of some covariant algebras are constructed. The generalization of the reflection equation to super case is given and the existence of the quasiclassical limits is pointed out. (orig.)

  14. Real-space renormalization group; application to site percolation in square lattice

    International Nuclear Information System (INIS)

    Tsallis, C.; Schwachheim, G.

    1978-05-01

    The real-space renormalization group proposed by Reynolds, Klein and Stanley 1977 to treat the site percolation is analysed and extended . The best among 3 possible definitions of 'percolating' configurations and among 5 possible methods to weight these configurations, are established for percolation in square lattices. The use of n xn square clusters leads, for n = 2 (RKS), n = 3 and n = 4, to √ sub (p) approximately equal to 1.635, √ sub(p) approximately equal to 1.533 and √ sub(p) approximately equal to 1.498, and also to P sub(c) approximately equal to 0.382, P sub(c) approximately equal to 0.388 and P sub(c) approximately equal to 0.398, exhibiting in this way the correct (but slow) tendency towards the best up to date values [pt

  15. Space Interferometry Science Working Group

    Science.gov (United States)

    Ridgway, Stephen T.

    1992-12-01

    Decisions taken by the astronomy and astrophysics survey committee and the interferometry panel which lead to the formation of the Space Interferometry Science Working Group (SISWG) are outlined. The SISWG was formed by the NASA astrophysics division to provide scientific and technical input from the community in planning for space interferometry and in support of an Astrometric Interferometry Mission (AIM). The AIM program hopes to measure the positions of astronomical objects with a precision of a few millionths of an arcsecond. The SISWG science and technical teams are described and the outcomes of its first meeting are given.

  16. Group-velocity dispersion effects on quantum noise of a fiber optical soliton in phase space

    International Nuclear Information System (INIS)

    Ju, Heongkyu; Lee, Euncheol

    2010-01-01

    Group-velocity dispersion (GVD) effects on quantum noise of ultrashort pulsed light are theoretically investigated at the soliton energy level, using Gaussian-weighted pseudo-random distribution of phasors in phase space for the modeling of quantum noise properties including phase noise, photon number noise, and quantum noise shape in phase space. We present the effects of GVD that mixes the different spectral components in time, on the self-phase modulation(SPM)-induced quantum noise properties in phase space such as quadrature squeezing, photon-number noise, and tilting/distortion of quantum noise shape in phase space, for the soliton that propagates a distance of the nonlinear length η NL = 1/( γP 0 ) (P 0 is the pulse peak power and γ is the SPM parameter). The propagation dependence of phase space quantum noise properties for an optical soliton is also provided.

  17. Symmetries of quantum spaces. Subgroups and quotient spaces of quantum SU(2) and SO(3) groups

    International Nuclear Information System (INIS)

    Podles, P.

    1995-01-01

    We prove that each action of a compact matrix quantum group on a compact quantum space can be decomposed into irreducible representations of the group. We give the formula for the corresponding multiplicities in the case of the quotient quantum spaces. We describe the subgroups and the quotient spaces of quantum SU(2) and SO(3) groups. (orig.)

  18. Vinorine synthase from Rauvolfia: the first example of crystallization and preliminary X-ray diffraction analysis of an enzyme of the BAHD superfamily.

    Science.gov (United States)

    Ma, Xueyan; Koepke, Juergen; Bayer, Anja; Linhard, Verena; Fritzsch, Günter; Zhang, Bin; Michel, Hartmut; Stöckigt, Joachim

    2004-09-01

    Crystals of vinorine synthase (VS) from medicinal plant Rauvolfia serpentina expressed in Escherichia coli have been obtained by the hanging-drop technique at 305 K with ammonium sulfate and PEG 400 as precipitants. The enzyme is involved in the biosynthesis of the antiarrhythmic drug ajmaline and is a member of the BAHD superfamily of acyltransferases. So far, no three-dimensional structure of a member of this enzyme family is known. The crystals belong to the space group P2(1)2(1)2(1) with cell dimensions of a=82.3 A, b=89.6 A and c=136.2 A. Under cryoconditions (120 K), a complete data set up to 2.8 A was collected at a synchrotron source.

  19. Purification, crystallization and preliminary X-ray diffraction analysis of GatD, a glutamine amidotransferase-like protein from Staphylococcus aureus peptidoglycan.

    Science.gov (United States)

    Vieira, Diana; Figueiredo, Teresa A; Verma, Anil; Sobral, Rita G; Ludovice, Ana M; de Lencastre, Hermínia; Trincao, Jose

    2014-05-01

    Amidation of peptidoglycan is an essential feature in Staphylococcus aureus that is necessary for resistance to β-lactams and lysozyme. GatD, a 27 kDa type I glutamine amidotransferase-like protein, together with MurT ligase, catalyses the amidation reaction of the glutamic acid residues of the peptidoglycan of S. aureus. The native and the selenomethionine-derivative proteins were crystallized using the sitting-drop vapour-diffusion method with polyethylene glycol, sodium acetate and calcium acetate. The crystals obtained diffracted beyond 1.85 and 2.25 Å, respectively, and belonged to space group P212121. X-ray diffraction data sets were collected at Diamond Light Source (on beamlines I02 and I04) and were used to obtain initial phases.

  20. Expression, purification and crystallization of pecan (Carya illinoinensis) vicilin.

    Science.gov (United States)

    Lee, BoRam; Zhang, Renhao; Du, Wen-Xian; Grauke, Larry J; McHugh, Tara H; Zhang, Yu-Zhu

    2014-08-01

    Tree nuts are responsible for many cases of severe food allergies. The 7S seed storage protein vicilin has been identified as a food allergen in many kinds of tree nuts. The vicilin protein consists of an N-terminal low-complexity region with antimicrobial activity and a C-terminal domain that forms a trimeric structure that belongs to the cupin superfamily. In this study, vicilin from pecan (Carya illinoinensis) was isolated and was expressed in bacteria for the first time. The cupin structural core of the protein, residues 369-792, was purified by metal-affinity and gel-filtration chromatography to high purity. Vicilin crystals were obtained and the best crystal diffracted to 2.65 Å resolution in space group P212121.

  1. The entire sequence over Musielak p-metric space

    Directory of Open Access Journals (Sweden)

    C. Murugesan

    2016-04-01

    Full Text Available In this paper, we introduce fibonacci numbers of Γ2(F sequence space over p-metric spaces defined by Musielak function and examine some topological properties of the resulting these spaces.

  2. Professional Discussion Groups: Informal Learning in a Third Space

    Science.gov (United States)

    Jordan, Robert A.

    2013-01-01

    In this ethnographic study, I explored two discussion groups and discovered Third Space elements such as cultural hybridity, counterscript, and sharing of experiences and resources contributed to a safe learning environment existing at the boundaries between participant personal and professional spaces. The groups operated under the auspices of a…

  3. Crystal engineering of ibuprofen compounds: From molecule to crystal structure to morphology prediction by computational simulation and experimental study

    Science.gov (United States)

    Zhang, Min; Liang, Zuozhong; Wu, Fei; Chen, Jian-Feng; Xue, Chunyu; Zhao, Hong

    2017-06-01

    We selected the crystal structures of ibuprofen with seven common space groups (Cc, P21/c, P212121, P21, Pbca, Pna21, and Pbcn), which was generated from ibuprofen molecule by molecular simulation. The predicted crystal structures of ibuprofen with space group P21/c has the lowest total energy and the largest density, which is nearly indistinguishable with experimental result. In addition, the XRD patterns for predicted crystal structure are highly consistent with recrystallization from solvent of ibuprofen. That indicates that the simulation can accurately predict the crystal structure of ibuprofen from the molecule. Furthermore, based on this crystal structure, we predicted the crystal habit in vacuum using the attachment energy (AE) method and considered solvent effects in a systematic way using the modified attachment energy (MAE) model. The simulation can accurately construct a complete process from molecule to crystal structure to morphology prediction. Experimentally, we observed crystal morphologies in four different polarity solvents compounds (ethanol, acetonitrile, ethyl acetate, and toluene). We found that the aspect ratio decreases of crystal habits in this ibuprofen system were found to vary with increasing solvent relative polarity. Besides, the modified crystal morphologies are in good agreement with the observed experimental morphologies. Finally, this work may guide computer-aided design of the desirable crystal morphology.

  4. Group theoretical construction of planar noncommutative phase spaces

    Energy Technology Data Exchange (ETDEWEB)

    Ngendakumana, Ancille, E-mail: nancille@yahoo.fr; Todjihoundé, Leonard, E-mail: leonardt@imsp.uac.org [Institut de Mathématiques et des Sciences Physiques (IMSP), Porto-Novo (Benin); Nzotungicimpaye, Joachim, E-mail: kimpaye@kie.ac.rw [Kigali Institute of Education (KIE), Kigali (Rwanda)

    2014-01-15

    Noncommutative phase spaces are generated and classified in the framework of centrally extended anisotropic planar kinematical Lie groups as well as in the framework of noncentrally abelian extended planar absolute time Lie groups. Through these constructions the coordinates of the phase spaces do not commute due to the presence of naturally introduced fields giving rise to minimal couplings. By symplectic realizations methods, physical interpretations of generators coming from the obtained structures are given.

  5. Group theoretical construction of planar noncommutative phase spaces

    International Nuclear Information System (INIS)

    Ngendakumana, Ancille; Todjihoundé, Leonard; Nzotungicimpaye, Joachim

    2014-01-01

    Noncommutative phase spaces are generated and classified in the framework of centrally extended anisotropic planar kinematical Lie groups as well as in the framework of noncentrally abelian extended planar absolute time Lie groups. Through these constructions the coordinates of the phase spaces do not commute due to the presence of naturally introduced fields giving rise to minimal couplings. By symplectic realizations methods, physical interpretations of generators coming from the obtained structures are given

  6. On signature change in p-adic space-times

    International Nuclear Information System (INIS)

    Dragovic, B.G.

    1991-01-01

    Change of signature by linear coordinate transformations in p-adic space-times is considered. In this paper it is shown that there exists arbitrary change of trivial signature in Q p n for all n ≥ 1 if p ≡ 1 (mod 4). In other cases it is possible to change only even number of the signs of the signature. The authors suggest new concept of signature with respect to distinct quadratic extensions, of Q p . If space-time dimension is restricted to four there is no signature change

  7. 7 CFR 29.1166 - Primings (P Group).

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Primings (P Group). 29.1166 Section 29.1166... REGULATIONS TOBACCO INSPECTION Standards Grades § 29.1166 Primings (P Group). This group consists of round-tipped leaves from the lowest portion of the stalk. Leaves of the P group ripen prematurely as a result...

  8. Analysis of an industrial production suspension of Bacillus lentus subtilisin crystals by powder diffraction: a powerful quality-control tool.

    Science.gov (United States)

    Frankaer, Christian G; Moroz, Olga V; Turkenburg, Johan P; Aspmo, Stein I; Thymark, Majbritt; Friis, Esben P; Stahl, Kenny; Nielsen, Jens E; Wilson, Keith S; Harris, Pernille

    2014-04-01

    A microcrystalline suspension of Bacillus lentus subtilisin (Savinase) produced during industrial large-scale production was analysed by X-ray powder diffraction (XRPD) and X-ray single-crystal diffraction (MX). XRPD established that the bulk microcrystal sample representative of the entire production suspension corresponded to space group P212121, with unit-cell parameters a = 47.65, b = 62.43, c = 75.74 Å, equivalent to those for a known orthorhombic crystal form (PDB entry 1ndq). MX using synchrotron beamlines at the Diamond Light Source with beam dimensions of 20 × 20 µm was subsequently used to study the largest crystals present in the suspension, with diffraction data being collected from two single crystals (∼20 × 20 × 60 µm) to resolutions of 1.40 and 1.57 Å, respectively. Both structures also belonged to space group P2(1)2(1)2(1), but were quite distinct from the dominant form identified by XRPD, with unit-cell parameters a = 53.04, b = 57.55, c = 71.37 Å and a = 52.72, b = 57.13, c = 65.86 Å, respectively, and refined to R = 10.8% and Rfree = 15.5% and to R = 14.1% and Rfree = 18.0%, respectively. They are also different from any of the forms previously reported in the PDB. A controlled crystallization experiment with a highly purified Savinase sample allowed the growth of single crystals of the form identified by XRPD; their structure was solved and refined to a resolution of 1.17 Å with an R of 9.2% and an Rfree of 11.8%. Thus, there are at least three polymorphs present in the production suspension, albeit with the 1ndq-like microcrystals predominating. It is shown how the two techniques can provide invaluable and complementary information for such a production suspension and it is proposed that XRPD provides an excellent quality-control tool for such suspensions.

  9. Expression, purification, crystallization and preliminary X-ray analysis of conjugated polyketone reductase C2 (CPR-C2) from Candida parapsilosis IFO 0708.

    Science.gov (United States)

    Yamamura, Akihiro; Maruoka, Shintaro; Ohtsuka, Jun; Miyakawa, Takuya; Nagata, Koji; Kataoka, Michihiko; Kitamura, Nahoko; Shimizu, Sakayu; Tanokura, Masaru

    2009-11-01

    Conjugated polyketone reductase C2 (CPR-C2) from Candida parapsilosis IFO 0708 is a member of the NADPH-dependent aldo-keto reductase (AKR) superfamily and catalyzes the stereospecific reduction of ketopantoyl lactone to d-pantoyl lactone. A diffraction-quality crystal of recombinant CPR-C2 was obtained by the sitting-drop vapour-diffusion method using PEG 3350 as the precipitant. The crystal diffracted X-rays to 1.7 angstrom resolution on beamline NW12A of the Photon Factory-Advanced Ring (Tsukuba, Japan). The crystal belonged to space group P2(1)2(1)2(1), with unit-cell parameters a = 55.02, b = 68.30, c = 68.93 angstrom. The Matthews coefficient (V(M) = 1.76 angstrom(3) Da(-1)) indicated that the crystal contained one CPR-C2 molecule per asymmetric unit.

  10. Crystallization and preliminary X-ray crystallographic analysis of peptide deformylase from Pseudomonas aeruginosa.

    Science.gov (United States)

    Kim, Hyung-Wook; Han, Byung Woo; Yoon, Hye-Jin; Yang, Jin Kuk; Lee, Byung Il; Lee, Hyung Ho; Ahn, Hyung Jun; Suh, Se Won

    2002-10-01

    Peptide deformylase (PDF) from the pathogenic bacterium Pseudomonas aeruginosa has been overexpressed in Escherichia coli and crystallized in the presence of its inhibitor actinonin at 297 K using polyethylene glycol (PEG) 4000 as a precipitant. The diffraction limit and the spot shape of the crystals could be slightly improved by the crystal annealing/dehydration procedure. X-ray diffraction data to 1.85 A have been collected using synchrotron radiation. The crystal belongs to the orthorhombic space group P2(1)2(1)2(1), with unit-cell parameters a = 68.75, b = 74.46, c = 77.18 A. The asymmetric unit contains two subunits of peptide deformylase, with a corresponding crystal volume per protein mass (V(M)) of 2.45 A(3) Da(-1) and a solvent content of 49.8%.

  11. Optical Fiber Assemblies for Space Flight from the NASA Goddard Space Flight Center, Photonics Group

    Science.gov (United States)

    Ott, Melanie N.; Thoma, William Joe; LaRocca, Frank; Chuska, Richard; Switzer, Robert; Day, Lance

    2009-01-01

    The Photonics Group at NASA Goddard Space Flight Center in the Electrical Engineering Division of the Advanced Engineering and Technologies Directorate has been involved in the design, development, characterization, qualification, manufacturing, integration and anomaly analysis of optical fiber subsystems for over a decade. The group supports a variety of instrumentation across NASA and outside entities that build flight systems. Among the projects currently supported are: The Lunar Reconnaissance Orbiter, the Mars Science Laboratory, the James Webb Space Telescope, the Express Logistics Carrier for the International Space Station and the NASA Electronic Parts. and Packaging Program. A collection of the most pertinent information gathered during project support over the past year in regards to space flight performance of optical fiber components is presented here. The objective is to provide guidance for future space flight designs of instrumentation and communication systems.

  12. Non-Supramenable Groups Acting on Locally Compact Spaces

    DEFF Research Database (Denmark)

    Kellerhals, Julian; Monod, Nicolas; Rørdam, Mikael

    2013-01-01

    Supramenability of groups is characterised in terms of invariant measures on locally compact spaces. This opens the door to constructing interesting crossed product $C^*$-algebras for non-supramenable groups. In particular, stable Kirchberg algebras in the UCT class are constructed using crossed ...

  13. The birth of NASA the work of the Space Task Group, America's first true space pioneers

    CERN Document Server

    von Ehrenfried, Dutch

    2016-01-01

    This is the story of the work of the original NASA space pioneers; men and women who were suddenly organized in 1958 from the then National Advisory Committee on Aeronautics (NACA) into the Space Task Group. A relatively small group, they developed the initial mission concept plans and procedures for the U. S. space program. Then they boldly built hardware and facilities to accomplish those missions. The group existed only three years before they were transferred to the Manned Spacecraft Center in Houston, Texas, in 1962, but their organization left a large mark on what would follow. Von Ehrenfried's personal experience with the STG at Langley uniquely positions him to describe the way the group was structured and how it reacted to the new demands of a post-Sputnik era. He artfully analyzes how the growing space program was managed and what techniques enabled it to develop so quickly from an operations perspective. The result is a fascinating window into history, amply backed up by first person documentation ...

  14. The space shuttle payload planning working groups: Volume 9: Materials processing and space manufacturing

    Science.gov (United States)

    1973-01-01

    The findings and recommendations of the Materials Processing and Space Manufacturing group of the space shuttle payload planning activity are presented. The effects of weightlessness on the levitation processes, mixture stability, and control over heat and mass transport in fluids are considered for investigation. The research and development projects include: (1) metallurgical processes, (2) electronic materials, (3) biological applications, and (4)nonmetallic materials and processes. Additional recommendations are provided concerning the allocation of payload space, acceptance of experiments for flight, flight qualification, and private use of the space shuttle.

  15. Projective unitary-antiunitary representations of the Shubnikov space groups

    International Nuclear Information System (INIS)

    Broek, P.M. van den.

    1979-01-01

    Some mathematical aspects of the symmetry of a physical system in quantum mechanics are examined with special emphasis on the symmetry groups of charged particles in crystalline solids, the Shuknikov space groups. (Auth.)

  16. Contribution of on-site Coulomb repulsion energy to structural, electronic and magnetic properties of SrCoO3 for different space groups: first-principles study

    Directory of Open Access Journals (Sweden)

    Muhammady Shibghatullah

    2018-03-01

    Full Text Available We report structural, electronic, and magnetic properties of SrCoO3 in Pm3̅m and P4/mbm space groups, which are calculated by using generalized gradient approximation corrected with on-site Coulomb repulsion U and exchange energies J. The cubic lattice parameter a and local magnetic moments of Co (μCo are optimized by varying U at Co 3d site. Employing ultrasoft pseudopotential, the values of U = 8 eV and J = 0.75 eV are the best choice for Pm3̅m space group. We found the value of μCo = 2.56 μB, which is consistent with the previous results. It was also found that Co 3d, hybridized with O 2p, is the main contributor to ferromagnetic metallic properties. Besides, norm-conserving pseudopotential promotes a, which is in good agreement with experimental result. However, it is not suitable for P4/mbm space group. By using ultrasoft pseudopotential, the value of U = 3 eV (J = 0.75 is the most suitable for P4/mbm group. Ferromagnetic metallic properties, Jahn-Teller distortion, and reasonable lattice parameters have been obtained. This study shows that U has significant contribution to the calculated properties and also points out that P4/mbm space group with US-PP is suitable to describe experimental results.

  17. Crystallization and preliminary X-ray crystallographic analysis of peptide deformylase (PDF) from Bacillus cereus in ligand-free and actinonin-bound forms.

    Science.gov (United States)

    Park, Joon Kyu; Moon, Jin Ho; Kim, Jae-Hong; Kim, Eunice EunKyeong

    2005-01-01

    In bacteria, protein expression initiates with an N-formyl group and this needs to be removed in order to ensure proper bacterial growth. These formylation and deformylation processes are unique to eubacteria; therefore, inhibition of these would provide a novel antibacterial therapy. Deformylation is carried out by peptide deformylase (PDF). PDF from Bacillus cereus, one of the major pathogenic bacteria, was cloned into expression plasmid pET-28a (Novagen), overexpressed in Escherichia coli BL21 (DE3) and purified to high quality. Crystals have been obtained of both ligand-free PDF and PDF to which actinonin, a highly potent naturally occurring inhibitor, is bound. Both crystals belong to space group P2(1)2(1)2(1), with unit-cell parameters a = 42.72, b = 44.04, c = 85.19 A and a = 41.31, b = 44.56, c = 84.47 A, respectively. Diffraction data were collected to 1.7 A resolution for the inhibitor-free crystals and to 2.0 A resolution for the actinonin-bound crystals.

  18. Student "Facebook" Groups as a Third Space: Between Social Life and Schoolwork

    Science.gov (United States)

    Aaen, Janus; Dalsgaard, Christian

    2016-01-01

    The paper examines educational potentials of "Facebook" groups that are created and managed by students without any involvement from teachers. The objective is to study student-managed "Facebook" groups as a "third space" between the institutional space of teacher-managed "Facebook" groups and the…

  19. Renormalization group in statistical physics - momentum and real spaces

    International Nuclear Information System (INIS)

    Yukalov, V.I.

    1988-01-01

    Two variants of the renormalization group approach in statistical physics are considered, the renormalization group in the momentum and the renormalization group in the real spaces. Common properties of these methods and their differences are cleared up. A simple model for investigating the crossover between different universality classes is suggested. 27 refs

  20. Copper-based metal coordination complexes with Voriconazole ligand: Syntheses, structures and antimicrobial properties

    Science.gov (United States)

    Zhao, Yan-Ming; Tang, Gui-Mei; Wang, Yong-Tao; Cui, Yue-Zhi; Ng, Seik Weng

    2018-03-01

    Three new chiral metal coordination complexes, namely, [Cu(FZ)2(CH3COO)2(H2O)]·2H2O (1), [Cu(FZ)2(NO3)2] (2), and [Cu2(FZ)2 (H2O)8](SO4)2·4H2O (3) [FZ = (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidiny)-1-(1H-1,2,4-triazol-1-yl)-2-butanol) (Voriconazole)] have been obtained by the reaction of Cu(II) salts and the free ligand FZ at room temperature. Complexes 1-3 were structurally characterized by X-ray single-crystal diffraction, IR, UV-vis, powder X-ray diffraction (PXRD), and thermogravimetric analysis (TGA). Complex 1 crystallizes in the chiral space group C2, which exhibits a mono-nuclear structure. Both complexes 2 and 3 display a one-dimensional (1D) tape structure, which crystallize in chiral space group P21212 and P212121, respectively. Among these complexes, there exist a variety of hydrogen bonds and stacking interactions, through which a three-dimensional supramolecular architecture will be generated. Compared with the standard (Voriconazole), these Cu-based complexes show the more potent inhibiting efficiency against the species of Candida and Aspergillus. Moreover, among these complexes, complex 1 shows the most excellent efficiency.

  1. P-adic space-time and string theory

    International Nuclear Information System (INIS)

    Volovich, I.V.

    1987-01-01

    Arguments for the possibility of a p-adic structure of space-time are advanced. The p-adic analog of the Veneziano amplitude is proposed, and this permits a start to be made on the construction of the theory of p-adic strings. The same questions are considered over Galois fields, for which the analog of the Veneziano amplitude is a Jacobi sum that can be expressed in terms of p-adic cohomologies of Fermat curves. An explicit expression for the vertex operator of the corresponding string theory is given

  2. Potassium tetracyanidoaurate(III monohydrate: a redetermination

    Directory of Open Access Journals (Sweden)

    Nobuyuki Matsushita

    2017-03-01

    Full Text Available The structure of the title metal complex salt, K[Au(CN4]·H2O, has been redetermined using X-ray diffraction data at 173 K in order to improve the precision. The previous determination was based on neutron diffraction data [Bertinotti & Bertinotti (1970. Acta Cryst. B26, 422–428]. The title compound crystallizes in the space group P212121 with one potassium cation, one [Au(CN4]− anion and one water molecule in the asymmetric unit. The AuIII atom lies on a general position and has an almost square-planar coordination sphere defined by four cyanide ligands. Interactions between the potassium cation and N atoms of the complex anion, as well as O—H...N hydrogen bonds, lead to the formation of a three-dimensional framework structure.

  3. Some p-ranks related to orthogonal spaces

    NARCIS (Netherlands)

    Blokhuis, A.; Moorhouse, G.E.

    1995-01-01

    We determine the p-rank of the incidence matrix of hyperplanes of PG(n, p e) and points of a nondegenerate quadric. This yields new bounds for ovoids and the size of caps in finite orthogonal spaces. In particular, we show the nonexistence of ovoids in O10+ (2e ),O10+ (3e ),O9 (5e ),O12+ (5e

  4. Groups, matrices, and vector spaces a group theoretic approach to linear algebra

    CERN Document Server

    Carrell, James B

    2017-01-01

    This unique text provides a geometric approach to group theory and linear algebra, bringing to light the interesting ways in which these subjects interact. Requiring few prerequisites beyond understanding the notion of a proof, the text aims to give students a strong foundation in both geometry and algebra. Starting with preliminaries (relations, elementary combinatorics, and induction), the book then proceeds to the core topics: the elements of the theory of groups and fields (Lagrange's Theorem, cosets, the complex numbers and the prime fields), matrix theory and matrix groups, determinants, vector spaces, linear mappings, eigentheory and diagonalization, Jordan decomposition and normal form, normal matrices, and quadratic forms. The final two chapters consist of a more intensive look at group theory, emphasizing orbit stabilizer methods, and an introduction to linear algebraic groups, which enriches the notion of a matrix group. Applications involving symm etry groups, determinants, linear coding theory ...

  5. A Phase Transformation with no Change in Space Group Symmetry: Octafluoronaphtalene

    DEFF Research Database (Denmark)

    Pawley, G. S.; Dietrich, O. W.

    1975-01-01

    A solid-state phase transformation in octafluoronaphthalene has been discovered at 266.5K on cooling, and at 15K higher on heating. The symmetry of both phases is found to be the same, namely monoclinic with space group P21/c. The unit cell parameters change by up to 10%, but the integrity...... of a single crystal, which shatters on cooling, is good enough for a single-crystal structure determination. This has been done in both phases to a sufficient accuracy that a mechanism for the transformation can be proposed. Molecules which lie parallel to one another shear to a new parallel position...

  6. System theory on group manifolds and coset spaces.

    Science.gov (United States)

    Brockett, R. W.

    1972-01-01

    The purpose of this paper is to study questions regarding controllability, observability, and realization theory for a particular class of systems for which the state space is a differentiable manifold which is simultaneously a group or, more generally, a coset space. We show that it is possible to give rather explicit expressions for the reachable set and the set of indistinguishable states in the case of autonomous systems. We also establish a type of state space isomorphism theorem. Our objective is to reduce all questions about the system to questions about Lie algebras generated from the coefficient matrices entering in the description of the system and in that way arrive at conditions which are easily visualized and tested.

  7. Derivation of space groups in mm2, 222 and mmm crystal classes

    International Nuclear Information System (INIS)

    Nigam, G.D.

    1987-08-01

    An algebraic approach is developed to derive space groups using 4x4 Seitz matrices for the crystal classes mm2, 222 and mmm in the orthorhombic system. The advantage of the present method is that it is relatively simple and can be adapted to introduce space groups to beginners. One of the advantages of the present method is that it admits a geometrical visualization of the symmetry elements of space group. The method can easily be extended to other crystal classes in a straightforward way. 16 refs, 1 fig., 2 tabs

  8. The cohomology of orbit spaces of certain free circle group actions

    Indian Academy of Sciences (India)

    Abstract. Suppose that G = S1 acts freely on a finitistic space X whose (mod p) cohomology ring is isomorphic to that of a lens space L2m−1(p;q1,...,qm) or S1 ×. CPm−1. The mod p index of the action is defined to be the largest integer n such that αn = 0, where α ϵ H2(X/G; Zp) is the nonzero characteristic class of the S1-.

  9. A second orthorhombic polymorph of (Z-3-(9-anthryl-1-(2-thienylprop-2-en-1-oneThis paper is dedicated to His Majesty King Bhumibol Adulyadej of Thailand (King Rama IX for his sustainable development of the country.

    Directory of Open Access Journals (Sweden)

    Suchada Chantrapromma

    2010-02-01

    Full Text Available The title heteroaryl chalcone, C21H14OS, is a second orthorhombic polymorph which crystallizes in the space group P212121. The structure was previously reported [Fun et al. (2009. Acta Cryst. E65, o2168-o2169] in the space group Pna21. The bond distances and angles are similar in both structures. In contrast, the overall crystal packing is different from that in the first orthorhombic Pna21 polymorph in which molecules were stacked into columns along the b axis and the thiophene units of two adjacent columns were stacked in a head to tail fashion. In the present polymorph, molecules are found to dimerize through a weak S...S interaction [3.6513 (7 Å] and these dimers are arranged into sheets parallel to the bc plane. There are no classical hydrogen bonds in the packing which features short C...O [3.2832 (2–3.6251 (9 Å], C...S [3.4879 (17–3.6251 (19 Å] and S...O [2.9948 (16 Å] contacts, together with C—H...π interactions. Similar contacts were found in the other polymorph.

  10. METHOD OF GROUP OBJECTS FORMING FOR SPACE-BASED REMOTE SENSING OF THE EARTH

    Directory of Open Access Journals (Sweden)

    A. N. Grigoriev

    2015-07-01

    Full Text Available Subject of Research. Research findings of the specific application of space-based optical-electronic and radar means for the Earth remote sensing are considered. The subject matter of the study is the current planning of objects survey on the underlying surface in order to increase the effectiveness of sensing system due to the rational use of its resources. Method. New concept of a group object, stochastic swath and stochastic length of the route is introduced. The overview of models for single, group objects and their parameters is given. The criterion for the existence of the group object based on two single objects is formulated. The method for group objects formation while current survey planning has been developed and its description is presented. The method comprises several processing stages for data about objects with the calculation of new parameters, the stochastic characteristics of space means and validates the spatial size of the object value of the stochastic swath and stochastic length of the route. The strict mathematical description of techniques for model creation of a group object based on data about a single object and onboard special complex facilities in difficult conditions of registration of spatial data is given. Main Results. The developed method is implemented on the basis of modern geographic information system in the form of a software tool layout with advanced tools of processing and analysis of spatial data in vector format. Experimental studies of the forming method for the group of objects were carried out on a different real object environment using the parameters of modern national systems of the Earth remote sensing detailed observation Canopus-B and Resurs-P. Practical Relevance. The proposed models and method are focused on practical implementation using vector spatial data models and modern geoinformation technologies. Practical value lies in the reduction in the amount of consumable resources by means of

  11. Differential calculus on quantum spaces and quantum groups

    International Nuclear Information System (INIS)

    Zumino, B.

    1992-01-01

    A review of recent developments in the quantum differential calculus. The quantum group GL q (n) is treated by considering it as a particular quantum space. Functions on SL q (n) are defined as a subclass of functions on GL q (n). The case of SO q (n) is also briefly considered. These notes cover part of a lecture given at the XIX International Conference on Group Theoretic Methods in Physics, Salamanca, Spain 1992

  12. The crystallographic space groups and Heterotic string theory

    International Nuclear Information System (INIS)

    El Naschie, M.S.

    2009-01-01

    While the 17 planar crystallographic groups were shown to correspond to 17 two and three Stein spaces with a total dimension equal to DimE12=5α-bar o ≅685, the present work reveals that the corresponding 219 three dimensional groups leads to a total dimensionality equal to N o ≅8872 which happens to be the exact total number of massless states of the transfinite version of Heterotic super string spectrum.

  13. Structure of the I-SceI nuclease complexed with its dsDNA target and three catalytic metal ions

    DEFF Research Database (Denmark)

    Prieto, Jesús; Redondo, Pilar; Merino, Nekane

    2016-01-01

    Homing endonucleases are highly specific DNA-cleaving enzymes that recognize and cleave long stretches of DNA. The engineering of these enzymes provides instruments for genome modification in a wide range of fields, including gene targeting. The homing endonuclease I-SceI from the yeast Saccharom......Homing endonucleases are highly specific DNA-cleaving enzymes that recognize and cleave long stretches of DNA. The engineering of these enzymes provides instruments for genome modification in a wide range of fields, including gene targeting. The homing endonuclease I-SceI from the yeast...... experiments were performed in the presence of Mn(2+), yielding crystals that were suitable for X-ray diffraction analysis. The crystals belonged to the orthorhombic space group P212121, with unit-cell parameters a = 80.11, b = 80.57, c = 130.87 Å, α = β = γ = 90°. The self-rotation function and the Matthews...

  14. COSTANZA, 1-D 2 Group Space-Dependent Reactor Dynamics of Spatial Reactor with 1 Group Delayed Neutrons

    International Nuclear Information System (INIS)

    Agazzi, A.; Gavazzi, C.; Vincenti, E.; Monterosso, R.

    1964-01-01

    1 - Nature of physical problem solved: The programme studies the spatial dynamics of reactor TESI, in the two group and one space dimension approximation. Only one group of delayed neutrons is considered. The programme simulates the vertical movement of the control rods according to any given movement law. The programme calculates the evolution of the fluxes and temperature and precursor concentration in space and time during the power excursion. 2 - Restrictions on the complexity of the problem: The maximum number of lattice points is 100

  15. On phase transitions in NH_{4HSeO4} and ND{4}DSeO{4}

    Science.gov (United States)

    Dvořák, V.; Quilichini, M.; Le Calvé, N.; Pasquier, B.; Heger, G.; Schweiss, P.

    1991-10-01

    We propose a hypothetical prototype phase (space group Imm) from which all observed phases in NH{4}HSeO{4} and ND{4}DSeO{4} can be deduced by introducing order parameters of definite symmetries. Following this hypothesis the symmetry of the superionic phase should be P2/n in disagreement with recent experimental results. Free energies of Landau type are derived by means of which particular phase transitions could be described. The large dielectric anomaly near 252 K in NH{4}HSeO{4} is discussed in some detail. The first order phase transition in ND{4}DSeO{4} from the room temperature phase P2{1}2121 into commensurate lock-in phase (with the wave-vector k {z}(0,0, frac{π}{c})) has been investigated by neutron elastic scattering and the symmetry of the latter has been found to be P112{1} in agreement with our theoretical prediction. Nous proposons une phase prototype hypothétique (de groupe d'espace Immm) à partir de laquelle on peut déduire toutes les phases observées dans NH{4}HSeO{4} et ND{4}DSeO{4} par l'introduction de paramètres d'ordre ayant une symétrie définie. D'après cette hypothèse le groupe d'espace de la phase superionique doit être P2/n ce qui est en désaccord avec des résultats expérimentaux récents. Pour chaque transition de phase on écrit l'énergie libre de type Landau à partir de laquelle elle peut être décrite. La grande anomalie diélectrique au voisinage de 252 K dans le composé NH{4}HSeO{4} est discutée de façon détaillée. Dans le composé ND{4}DSeO{4}, nous avons étudié par diffusion élastique de neutrons la transition de phase du premier ordre qui transforme le cristal de la structure P2{1}2121 dans la phase commensurable d'accrochage (de vecteur d'onde k {z}(0,0, frac{π}{c})). Nous avons montré que la symétrie de cette phase est P112{1}, ce qui en accord avec nos prévisions théoriques.

  16. On the Chabauty space of locally compact abelian groups

    OpenAIRE

    Cornulier, Yves

    2010-01-01

    This paper contains several results about the Chabauty space of a general locally compact abelian group. Notably, we determine its topological dimension, we characterize when it is totally disconnected or connected; we characterize isolated points.

  17. Toward a standardized structural-functional group connectome in MNI space.

    Science.gov (United States)

    Horn, Andreas; Blankenburg, Felix

    2016-01-01

    The analysis of the structural architecture of the human brain in terms of connectivity between its subregions has provided profound insights into its underlying functional organization and has coined the concept of the "connectome", a structural description of the elements forming the human brain and the connections among them. Here, as a proof of concept, we introduce a novel group connectome in standard space based on a large sample of 169 subjects from the Enhanced Nathan Kline Institute-Rockland Sample (eNKI-RS). Whole brain structural connectomes of each subject were estimated with a global tracking approach, and the resulting fiber tracts were warped into standard stereotactic (MNI) space using DARTEL. Employing this group connectome, the results of published tracking studies (i.e., the JHU white matter and Oxford thalamic connectivity atlas) could be largely reproduced directly within MNI space. In a second analysis, a study that examined structural connectivity between regions of a functional network, namely the default mode network, was reproduced. Voxel-wise structural centrality was then calculated and compared to others' findings. Furthermore, including additional resting-state fMRI data from the same subjects, structural and functional connectivity matrices between approximately forty thousand nodes of the brain were calculated. This was done to estimate structure-function agreement indices of voxel-wise whole brain connectivity. Taken together, the combination of a novel whole brain fiber tracking approach and an advanced normalization method led to a group connectome that allowed (at least heuristically) performing fiber tracking directly within MNI space. Such an approach may be used for various purposes like the analysis of structural connectivity and modeling experiments that aim at studying the structure-function relationship of the human connectome. Moreover, it may even represent a first step toward a standard DTI template of the human brain

  18. Atomic resolution studies of haloalkane dehalogenases DhaA04, DhaA14 and DhaA15 with engineered access tunnels.

    Science.gov (United States)

    Stsiapanava, A; Dohnalek, J; Gavira, J A; Kuty, M; Koudelakova, T; Damborsky, J; Kuta Smatanova, I

    2010-09-01

    The haloalkane dehalogenase DhaA from Rhodococcus rhodochrous NCIMB 13064 is a bacterial enzyme that shows catalytic activity for the hydrolytic degradation of the highly toxic industrial pollutant 1,2,3-trichloropropane (TCP). Mutagenesis focused on the access tunnels of DhaA produced protein variants with significantly improved activity towards TCP. Three mutants of DhaA named DhaA04 (C176Y), DhaA14 (I135F) and DhaA15 (C176Y + I135F) were constructed in order to study the functional relevance of the tunnels connecting the buried active site of the protein with the surrounding solvent. All three protein variants were crystallized using the sitting-drop vapour-diffusion technique. The crystals of DhaA04 belonged to the orthorhombic space group P2(1)2(1)2(1), while the crystals of DhaA14 and DhaA15 had triclinic symmetry in space group P1. The crystal structures of DhaA04, DhaA14 and DhaA15 with ligands present in the active site were solved and refined using diffraction data to 1.23, 0.95 and 1.22 A, resolution, respectively. Structural comparisons of the wild type and the three mutants suggest that the tunnels play a key role in the processes of ligand exchange between the buried active site and the surrounding solvent.

  19. [Preparation and characterization of Forms A and B of benazepril hydrochloride].

    Science.gov (United States)

    Fang, Hong; Hu, Xiu-rong; Gu, Jian-ming; Chen, Guan-xi; Feng, Jian-yue; Tang, Gu-ping

    2012-11-01

    To prepare Form A and Form B of benazepril hydrochloride and to compare the differences in spectrums, thermodynamics and crystal structure between two polymorphic forms. Form A and Form B of benazepril hydrochloride were characterized by Fourier transform infrared spectroscopy (IR), thermal gravimetric analysis (TG), differential scanning calorimetry (DSC), powder x-ray diffraction (PXRD) and single crystal x-ray diffraction (SCXRD). Preparation method, crystal structure and polymorphic stability of Form A and Form B of benazepril hydrochloride were obtained. Based on the analysis of crystal structure of both polymorphs, Form A belonged to monoclone space group P2(1) with a=7.8655(4)Å, b= 11.7700(6)Å, c= 13.5560(7)Å, β= 102.9470(10)°, V=1223.07 (11)Å(3) and Z=2, while Form B belonged to orthorhombic space group P212121, with a=7.9353(8)Å, b=11.6654(11)Å, c=26.6453(16)Å, V=2466.5(4)Å(3) and Z=4. From the DSC and XRD results, Form B of benazepril hydrochloride could be transformed into Form A after heating treatment. Form A and Form B of benazepril hydrochloride are both anhydrous and displayed different polymorphs due to different molecular configuration. Furthermore, Form A exhibits more stable than Form B at high temperatures.

  20. P-Adic analysis and the transfinite E8 exceptional Lie symmetry group unification

    Energy Technology Data Exchange (ETDEWEB)

    El Naschie, M.S. [King Abdullah Institute for Nano and Advanced Technology, KSU, Riyadh (Saudi Arabia)], E-mail: Chaossf@aol.com

    2008-11-15

    In P-Adic analysis like in a fractal Cantorian space there is no absolute scale. P-Adic analysis with its prime numbers base is the mathematical quarks of the exceptional E8 and E-infinity. The P-Adic space permits the use of Weyl original spacetime gauge theory which is the rationale behind E-infinity.

  1. P-Adic analysis and the transfinite E8 exceptional Lie symmetry group unification

    International Nuclear Information System (INIS)

    El Naschie, M.S.

    2008-01-01

    In P-Adic analysis like in a fractal Cantorian space there is no absolute scale. P-Adic analysis with its prime numbers base is the mathematical quarks of the exceptional E8 and E-infinity. The P-Adic space permits the use of Weyl original spacetime gauge theory which is the rationale behind E-infinity

  2. Using the 5 P Relay in Task Groups

    Science.gov (United States)

    Stanley, Paula Helen

    2006-01-01

    This article describes the 5 P Relay, a group exercise that can increase the effectiveness of task groups. The 5 P Relay is based on the principles and concepts of the Invitational Model, which emphasizes the importance of assessing the effectiveness or health of five aspects of an organization's environment: people, places, programs, processes,…

  3. Crystallization and preliminary x-ray structure analysis of the egg-white lysozyme from a Taiwanese Soft-Shelled Turtle (Tri onyx Sinensis Wiegmann)

    International Nuclear Information System (INIS)

    Siritapetawee, Jaruwan; Thammasirirak, Sompong; Yuvaniyama, Jirudon

    2005-10-01

    Lysozyme has been purified from the egg-white of a Taiwanese soft-shelled turtle. This soft-shelled turtle ' s egg-white lysozyme migrated on 12.5% SDS-PAGE at about 14.8 kDa. The lysozyme has been crystallized using the sitting drop vapor diffusion technique and 30% (w/v) polyethylene glycol 8000 in 0.1 M sodium cacodylate, p H 6.5 containing 0.2 M ammonium sulfate as a precipitant. One of the crystals diffracted X rays beyond 2 angstrom unit resolution and belonged to the orthorhombic, space group P212121, with unit cell dimensions of a = 37.8 angstrom unit, b = 55.6 angstrom unit, and c 72.2 angstrom unit and one molecule of the enzyme per asymmetric unit. The data were collected to 1.9 angstrom resolution with an R merge of 4.6%, suitable for high resolution structure analysis. The single-crystal X-ray structure of lysozyme has been initially phased with the Molecular Replacement technique using pheasant egg-white lysozyme (PDB ID 1GHL) as a search template. Model rebuilding and refinement are in progress

  4. Overexpression, crystallization and preliminary X-ray crystallographic analysis of erythronate-4-phosphate dehydrogenase from Pseudomonas aeruginosa.

    Science.gov (United States)

    Ha, Jun Yong; Lee, Ji Hyun; Kim, Kyoung Hoon; Kim, Do Jin; Lee, Hyung Ho; Kim, Hye-Kyung; Yoon, Hye-Jin; Suh, Se Won

    2006-02-01

    The enzyme erythronate-4-phosphate dehydrogenase catalyses the conversion of erythronate-4-phosphate to 3-hydroxy-4-phospho-hydroxy-alpha-ketobutyrate. It belongs to the D-isomer-specific 2-hydroxyacid dehydrogenase family. It is essential for de novo biosynthesis of vitamin B6 (pyridoxine). Erythronate-4-phosphate dehydrogenase from Pseudomonas aeruginosa, a homodimeric enzyme consisting of two identical 380-residue subunits, has been overexpressed in Escherichia coli with a C-terminal purification tag and crystallized at 297 K using 0.7 M ammonium dihydrogen phosphate, 0.4 M ammonium tartrate, 0.1 M sodium citrate pH 5.6 and 10 mM cupric chloride. X-ray diffraction data were collected to 2.20 A from a crystal grown in the presence of NADH. The crystals belong to the orthorhombic space group P2(1)2(1)2(1), with unit-cell parameters a = 84.77, b = 101.28, c = 142.58 A. A dimeric molecule is present in the asymmetric unit, giving a crystal volume per protein weight (VM) of 3.64 A3 Da(-1) and a solvent content of 66%.

  5. Vector-valued Lizorkin-Triebel spaces and sharp trace theory for functions in Sobolev spaces with mixed \\pmb{L_p}-norm for parabolic problems

    Science.gov (United States)

    Weidemaier, P.

    2005-06-01

    The trace problem on the hypersurface y_n=0 is investigated for a function u=u(y,t) \\in L_q(0,T;W_{\\underline p}^{\\underline m}(\\mathbb R_+^n)) with \\partial_t u \\in L_q(0,T; L_{\\underline p}(\\mathbb R_+^n)), that is, Sobolev spaces with mixed Lebesgue norm L_{\\underline p,q}(\\mathbb R^n_+\\times(0,T))=L_q(0,T;L_{\\underline p}(\\mathbb R_+^n)) are considered; here \\underline p=(p_1,\\dots,p_n) is a vector and \\mathbb R^n_+=\\mathbb R^{n-1} \\times (0,\\infty). Such function spaces are useful in the context of parabolic equations. They allow, in particular, different exponents of summability in space and time. It is shown that the sharp regularity of the trace in the time variable is characterized by the Lizorkin-Triebel space F_{q,p_n}^{1-1/(p_nm_n)}(0,T;L_{\\widetilde{\\underline p}}(\\mathbb R^{n-1})), \\underline p=(\\widetilde{\\underline p},p_n). A similar result is established for first order spatial derivatives of u. These results allow one to determine the exact spaces for the data in the inhomogeneous Dirichlet and Neumann problems for parabolic equations of the second order if the solution is in the space L_q(0,T; W_p^2(\\Omega)) \\cap W_q^1(0,T;L_p(\\Omega)) with p \\le q.

  6. An introduction to Lie groups and the geometry of homogeneous spaces

    CERN Document Server

    Arvanitoyeorgos, Andreas

    2003-01-01

    It is remarkable that so much about Lie groups could be packed into this small book. But after reading it, students will be well-prepared to continue with more advanced, graduate-level topics in differential geometry or the theory of Lie groups. The theory of Lie groups involves many areas of mathematics. In this book, Arvanitoyeorgos outlines enough of the prerequisites to get the reader started. He then chooses a path through this rich and diverse theory that aims for an understanding of the geometry of Lie groups and homogeneous spaces. In this way, he avoids the extra detail needed for a thorough discussion of other topics. Lie groups and homogeneous spaces are especially useful to study in geometry, as they provide excellent examples where quantities (such as curvature) are easier to compute. A good understanding of them provides lasting intuition, especially in differential geometry. The book is suitable for advanced undergraduates, graduate students, and research mathematicians interested in differenti...

  7. Effect of the spacer group nature on the optical and electrical properties of confined poly( p-phenylene vinylene) derivatives

    Science.gov (United States)

    Benzarti-Ghédira, Maha; Zahou, Imen; Hrichi, Haikel; Jaballah, Nejmeddine; Ben Chaâbane, Rafik; Majdoub, Mustapha; Ben Ouada, Hafedh

    2015-09-01

    This study is an investigation about the effect of chemical modification on the morphological, optical and electrical properties of semiconducting organic thin films. Two confined poly( p-phenylene vinylene) (PPV)-type polymers containing different spacer groups were studied: P1 has an isopropylidene spacer group and P2 with hexafluoroisopropylidene spacer. The UV-Vis absorption and PL analysis showed a stronger π- π interaction in the P1 film; in P2, the π-stacking is limited by the introduction of a bulky trifluoromethyl (CF3) groups on the spacer units. The P2 exhibits a better film quality as illustrated by the atomic force microscopy. The HOMO and LUMO energy levels and electrochemical band gap of the polymers were determinate by the cyclic voltammetry. The electrical properties of ITO/PPV derivative/Al diodes were investigated by means of current-voltage and show a space-charge-limited current conduction mechanism with higher mobility in the P2 thin layer. The impedance spectra of the devices can be discussed in terms of an equivalent circuit model designed as a parallel resistance ( R p) and capacitance ( C p) network in series with a resistance.

  8. Determining sociability, social space, and social presence in (a)synchronous collaborative groups.

    Science.gov (United States)

    Kreijns, Karel; Kirschner, Paul A; Jochems, Wim; Van Buuren, Hans

    2004-04-01

    The effectiveness of group learning in asynchronous distributed learning groups depends on the social interaction that takes place. This social interaction affects both cognitive and socioemotional processes that take place during learning, group forming, establishment of group structures, and group dynamics. Though now known to be important, this aspect is often ignored, denied or forgotten by educators and researchers who tend to concentrate on cognitive processes and on-task contexts. This "one-sided" educational focus largely determines the set of requirements in the design of computer-supported collaborative learning (CSCL) environments resulting in functional CSCL environments. In contrast, our research is aimed at the design and implementation of sociable CSCL environments which may increase the likelihood that a sound social space will emerge. We use a theoretical framework that is based upon an ecological approach to social interaction, centering on the concept of social affordances, the concept of the sociability of CSCL environments, and social presence theory. The hypothesis is that the higher the sociability, the more likely that social interaction will take place or will increase, and the more likely that this will result in an emerging sound social space. In the present research, the variables of interest are sociability, social space, and social presence. This study deals with the construction and validation of three instruments to determine sociability, social space, and social presence in (a)synchronous collaborating groups. The findings suggest that the instruments have potential to be useful as measures for the respective variables. However, it must be realized that these measures are "first steps."

  9. Unitary Representations of Gauge Groups

    Science.gov (United States)

    Huerfano, Ruth Stella

    I generalize to the case of gauge groups over non-trivial principal bundles representations that I. M. Gelfand, M. I. Graev and A. M. Versik constructed for current groups. The gauge group of the principal G-bundle P over M, (G a Lie group with an euclidean structure, M a compact, connected and oriented manifold), as the smooth sections of the associated group bundle is presented and studied in chapter I. Chapter II describes the symmetric algebra associated to a Hilbert space, its Hilbert structure, a convenient exponential and a total set that later play a key role in the construction of the representation. Chapter III is concerned with the calculus needed to make the space of Lie algebra valued 1-forms a Gaussian L^2-space. This is accomplished by studying general projective systems of finitely measurable spaces and the corresponding systems of sigma -additive measures, all of these leading to the description of a promeasure, a concept modeled after Bourbaki and classical measure theory. In the case of a locally convex vector space E, the corresponding Fourier transform, family of characters and the existence of a promeasure for every quadratic form on E^' are established, so the Gaussian L^2-space associated to a real Hilbert space is constructed. Chapter III finishes by exhibiting the explicit Hilbert space isomorphism between the Gaussian L ^2-space associated to a real Hilbert space and the complexification of its symmetric algebra. In chapter IV taking as a Hilbert space H the L^2-space of the Lie algebra valued 1-forms on P, the gauge group acts on the motion group of H defining in an straight forward fashion the representation desired.

  10. Expression, purification, crystallization and crystallographic study of Lutzomyia longipalpis LJL143.

    Science.gov (United States)

    Kelleher, Alan; Liu, Zhuyun; Seid, Christopher A; Zhan, Bin; Asojo, Oluwatoyin A

    2015-07-01

    Leishmaniasis is a neglected vector-borne disease with a global prevalence of over 12 million cases and 59,000 annual deaths. Transmission of the parasite requires salivary proteins, including LJL143 from the New World sandfly Lutzomyia longipalpis. LJL143 is a known marker of sandfly exposure in zoonotic hosts. LJL143 was crystallized from soluble protein expressed using Pichia pastoris. X-ray data were collected to 2.6 Å resolution from orthorhombic crystals belonging to space group P2(1)2(1)2(1), with average unit-cell parameters a = 57.39, b = 70.24, c = 79.58 Å. The crystals are predicted to have a monomer in the asymmetric unit, with an estimated solvent content of 48.5%. LJL143 has negligible homology to any reported structures, so the phases could not be determined by molecular replacement. All attempts at S-SAD failed and future studies include experimental phase determination using heavy-atom derivatives.

  11. The homology groups of moduli spaces on non-classical Klein surfaces

    International Nuclear Information System (INIS)

    Zaw, Myint

    2001-08-01

    We describe the moduli space M-vector±(g,c) of non-classical directed Klein surfaces of genus g=h-c-1 with c≥0 distinguished points as a configuration space B ± (h,c) of classes h-slit pairs in C. Based on this model, we prove that M-vector ± (g,c) is non-orientable for any g and c and we compute the homology groups of the moduli spaces M-vector ± (g,c) for g≤2. (author)

  12. On classification of finite groups with four generators, three of which having orders p,p,q (p

    International Nuclear Information System (INIS)

    Yacoub, K.R.

    1984-03-01

    Finite groups with two independent generators attracted the attention of authors for several years. The author, having started on such groups in his PhD Thesis in 1953, discussed later on the existence and the structure of finite groups with three generators, one being of arbitrary order and the other two having given orders [Pub. Math. Debrecen, 11, 32-38(1964), 13, 9-16(1966)] and others. Recently, the author started the problem of finite groups with four generators a,b,c and d when b,c and d have the same odd prime order p. It is the object of the present paper to deal with a similar problem when the given orders are p, p and q with p q together with the particular case when m is an element of set containing p,q will be kept to a further discussion. The present paper consists actually of two main parts, the first deals with the case p does not divide q-1 while the second deals with the case p divides q-1. (author)

  13. Representation of SO(4,1) group and Hawking effect in the de-Sitter space

    International Nuclear Information System (INIS)

    Bogush, A.A.; Otchik, V.S.

    1983-01-01

    Expression relating the solution of the equation for particles with spin 1/2 to matrix elements of group SO(4, 1), is obtained. When using the relation of the Dirac equation solutions in the de Sitter space with matrix elements of representations of group SO(4, 1) the presence of the Hawking effect in the space is established. The de Sitter space is considered as 4-dimensional hyperboloid, inserted into 5-dimensional pseudo-Euclidean space. It is established, that the average number of emitted spinor particles obeys the Fermi-Dirac distribution

  14. Evaluation of the effects of subgingival injection of Simvastatin on space re-opening after orthodontic space closure in adults

    Directory of Open Access Journals (Sweden)

    Arezoo Jahanbin

    2016-03-01

    Full Text Available Background. This clinical trial evaluated the effect of Simvastatin on space re-opening after orthodontic space closure and its effect on the gingival index (GI and clinical attachment loss (CAL. Methods. 16 females, 25‒40 years old, with spaces between anterior mandibular teeth due to chronic periodontitis were participated in this study. The patients were randomly divided into control and experimental groups. In the experimental group, 1.2% Simvastatin gel and in the control group, 0.9% sodium chloride as a placebo was injected into the pocket depth of the six anterior teeth. The amount of space reopening, GI and CAL were measured. Results. No serious complications were observed during interventions and follow-up periods. Space re-opening was significantly reduced in patients receiving Simvastatin (P < 0.001. Moreover, GI reduction was significantly greater in Sim-vastatin group compared to the control group (P < 0.001. However, CAL did not demonstrate a significant difference between the groups. Conclusion. Simvastatin may decrease space re-opening after orthodontic space closure in human anterior teeth.

  15. Crystallization and preliminary X-ray diffraction analysis of the wild-type haloalkane dehalogenase DhaA and its variant DhaA13 complexed with different ligands.

    Science.gov (United States)

    Stsiapanava, Alena; Chaloupkova, Radka; Fortova, Andrea; Brynda, Jiri; Weiss, Manfred S; Damborsky, Jiri; Smatanova, Ivana Kuta

    2011-02-01

    Haloalkane dehalogenases make up an important class of hydrolytic enzymes which catalyse the cleavage of carbon-halogen bonds in halogenated aliphatic compounds. There is growing interest in these enzymes owing to their potential use in environmental and industrial applications. The haloalkane dehalogenase DhaA from Rhodococcus rhodochrous NCIMB 13064 can slowly detoxify the industrial pollutant 1,2,3-trichloropropane (TCP). Structural analysis of this enzyme complexed with target ligands was conducted in order to obtain detailed information about the structural limitations of its catalytic properties. In this study, the crystallization and preliminary X-ray analysis of complexes of wild-type DhaA with 2-propanol and with TCP and of complexes of the catalytically inactive variant DhaA13 with the dye coumarin and with TCP are described. The crystals of wild-type DhaA were plate-shaped and belonged to the triclinic space group P1, while the variant DhaA13 can form prism-shaped crystals belonging to the orthorhombic space group P2(1)2(1)2(1) as well as plate-shaped crystals belonging to the triclinic space group P1. Diffraction data for crystals of wild-type DhaA grown from crystallization solutions with different concentrations of 2-propanol were collected to 1.70 and 1.26 Å resolution, respectively. A prism-shaped crystal of DhaA13 complexed with TCP and a plate-shaped crystal of the same variant complexed with the dye coumarin diffracted X-rays to 1.60 and 1.33 Å resolution, respectively. A crystal of wild-type DhaA and a plate-shaped crystal of DhaA13, both complexed with TCP, diffracted to atomic resolutions of 1.04 and 0.97 Å, respectively.

  16. Working Group 2 summary: Space charge effects in bending systems

    International Nuclear Information System (INIS)

    Bohn, C.L.; Emma, P.J.

    2000-01-01

    At the start of the Workshop, the authors asked the Working Group 2 participants to concentrate on three basic goals: (1) survey the status of how comprehensively the physics concerning space-charge effects in bends is understood and how complete is the available ensemble of analytic and computational tools; (2) guided by data from experiments and operational experience, identify sources of, and cures for, beam degradation; and (3) review space-charge physics in rings and the limitations it introduces. As the Workshop unfolded, the third goal naturally folded into the other two goals, and these goals, they believe, were fulfilled in that the Working Group was able to compile an end product consisting of a set of recommendations for potentially fruitful future work. This summary constitutes an overview of the deliberations of the Working Group, and it is their hope that the summary clarifies the motivation for the recommended work listed at the end. The summary is organized according to the two aforementioned goals, and the prime topics of discussion appear as subsections under these goals

  17. GENERALIZED p-FORMS ELECTRODYNAMICS IN CLIFFORD SPACES

    CERN Document Server

    Castro, C

    2003-01-01

    Using Clifford algebraic methods we describe how to generalize Maxwell theory of Electrodynamics asociated with ordinary point-charges to a generalized Maxwell theory in Clifford spaces involving extended-charges and p-forms of arbitrary rank. Clifford algebras contain the appropriate algebraic-geometric features  to implement the principle of polydimensional transformations (branes of different dimensionality are rotated into each other) that could possibly lead to a proper formulation of string and M theory.

  18. Challenges in Teaching Space Physics to Different Target Groups From Space Weather Forecasters to Heavy-weight Theorists

    Science.gov (United States)

    Koskinen, H. E.

    2008-12-01

    Plasma physics as the backbone of space physics is difficult and thus the space physics students need to have strong foundations in general physics, in particular in classical electrodynamics and thermodynamics, and master the basic mathematical tools for physicists. In many universities the number of students specializing in space physics at Master's and Doctoral levels is rather small and the students may have quite different preferences ranging from experimental approach to hard-core space plasma theory. This poses challenges in building up a study program that has both the variety and depth needed to motivate the best students to choose this field. At the University of Helsinki we require all beginning space physics students, regardless whether they enter the field as Master's or Doctoral degree students, to take a one-semester package consisting of plasma physics and its space applications. However, some compromises are necessary. For example, it is not at all clear, how thoroughly Landau damping should be taught at the first run or how deeply should the intricacies of collisionless reconnection be discussed. In both cases we have left the details to an optional course in advanced space physics, even with the risk that the student's appreciation of, e.g., reconnection may remain at the level of a magic wand. For learning experimental work, data analysis or computer simulations we have actively pursued arrangements for the Master's degree students to get a summer employments in active research groups, which usually lead to the Master's theses. All doctoral students are members of research groups and participate in experimental work, data analysis, simulation studies or theory development, or any combination of these. We emphasize strongly "learning by doing" all the way from the weekly home exercises during the lecture courses to the PhD theses which in Finland consist typically of 4-6 peer-reviewed articles with a comprehensive introductory part.

  19. Real-space renormalization group approach to driven diffusive systems

    Energy Technology Data Exchange (ETDEWEB)

    Hanney, T [SUPA and School of Physics, University of Edinburgh, Mayfield Road, Edinburgh, EH9 3JZ (United Kingdom); Stinchcombe, R B [Theoretical Physics, 1 Keble Road, Oxford, OX1 3NP (United Kingdom)

    2006-11-24

    We introduce a real-space renormalization group procedure for driven diffusive systems which predicts both steady state and dynamic properties. We apply the method to the boundary driven asymmetric simple exclusion process and recover exact results for the steady state phase diagram, as well as the crossovers in the relaxation dynamics for each phase.

  20. Real-space renormalization group approach to driven diffusive systems

    International Nuclear Information System (INIS)

    Hanney, T; Stinchcombe, R B

    2006-01-01

    We introduce a real-space renormalization group procedure for driven diffusive systems which predicts both steady state and dynamic properties. We apply the method to the boundary driven asymmetric simple exclusion process and recover exact results for the steady state phase diagram, as well as the crossovers in the relaxation dynamics for each phase

  1. Generation of symmetry coordinates for crystals using multiplier representations of the space groups

    DEFF Research Database (Denmark)

    Hansen, Flemming Yssing

    1978-01-01

    Symmetry coordinates play an important role in the normal-mode calculations of crystals. It is therefore of great importance to have a general method, which may be applied for any crystal at any wave vector, to generate these. The multiplier representations of the space groups as given by Kovalev...... and the projection-operator technique provide a basis for such a method. The method is illustrated for the nonsymmorphic D36 space group, and the theoretical background for the representations of space groups in general is reviewed and illustrated on the example above. It is desirable to perform the projection...... of symmetry coordinates in such a way that they may be used for as many wave vectors as possible. We discuss how to achieve this goal. The detailed illustrations should make it simple to apply the theory in any other case....

  2. Group 5 allergens of timothy grass (Phl p 5) bear cross-reacting T cell epitopes with group 1 allergens of rye grass (Lol p 1).

    Science.gov (United States)

    Müller, W D; Karamfilov, T; Bufe, A; Fahlbush, B; Wolf, I; Jäger, L

    1996-04-01

    Selected human T cell clones reactive with group 5 allergens of timothy grass (Phl p 5) were cross-stimulated in specific proliferation assays with group 1 allergens of rye grass (Lol p 1). Such interspecies cross-reactivities result obviously from structural motifs presented on defined Phl p 5 fragments as shown with recombinant Phl p 5 products.

  3. A geometric renormalization group in discrete quantum space-time

    International Nuclear Information System (INIS)

    Requardt, Manfred

    2003-01-01

    We model quantum space-time on the Planck scale as dynamical networks of elementary relations or time dependent random graphs, the time dependence being an effect of the underlying dynamical network laws. We formulate a kind of geometric renormalization group on these (random) networks leading to a hierarchy of increasingly coarse-grained networks of overlapping lumps. We provide arguments that this process may generate a fixed limit phase, representing our continuous space-time on a mesoscopic or macroscopic scale, provided that the underlying discrete geometry is critical in a specific sense (geometric long range order). Our point of view is corroborated by a series of analytic and numerical results, which allow us to keep track of the geometric changes, taking place on the various scales of the resolution of space-time. Of particular conceptual importance are the notions of dimension of such random systems on the various scales and the notion of geometric criticality

  4. Space-charge-mediated anomalous ferroelectric switching in P(VDF-TrEE) polymer films

    KAUST Repository

    Hu, Weijin

    2014-11-12

    We report on the switching dynamics of P(VDF-TrEE) copolymer devices and the realization of additional substable ferroelectric states via modulation of the coupling between polarizations and space charges. The space-charge-limited current is revealed to be the dominant leakage mechanism in such organic ferroelectric devices, and electrostatic interactions due to space charges lead to the emergence of anomalous ferroelectric loops. The reliable control of ferroelectric switching in P(VDF-TrEE) copolymers opens doors toward engineering advanced organic memories with tailored switching characteristics.

  5. Fundamental group of dual graphs and applications to quantum space time

    International Nuclear Information System (INIS)

    Nada, S.I.; Hamouda, E.H.

    2009-01-01

    Let G be a connected planar graph with n vertices and m edges. It is known that the fundamental group of G has 1 -(n - m) generators. In this paper, we show that if G is a self-dual graph, then its fundamental group has (n - 1) generators. We indicate that these results are relevant to quantum space time.

  6. Synthesis and characterization of 6,6'-(2,4,6-triisopropylphenyl)-2,2'-bipyridine (tripbipy) and its complexes of the late first row transition metals.

    Science.gov (United States)

    Benson, Eric E; Rheingold, Arnold L; Kubiak, Clifford P

    2010-02-15

    The synthesis of tripbipy, a new substituted bipyridine ligand (6,6'-(2,4,6-triisopropylphenyl)-2,2'-bipyridine), and the syntheses, structures, and magnetic properties of the first coordination compounds based on this ligand are described. Tripbipy was synthesized by the Suzuki coupling of 2,4,6-triisopropylphenyl boronic acid and 6,6'-dibromo-2,2'-bipyridine. Reported here are the tripbipy complexes of five late first row transition metal chlorides (MCl(2); M = Fe, Co, Ni, Cu, Zn). Four of the complexes MCl(2)tripbipy (M = Fe, Co, Ni, Zn) crystallize in the space group P2(1)/c and are isomorphous with one solvent molecule of crystallization. The complex CuCl(2)tripbipy crystallizes in the space group P2(1)2(1)2(1) with two solvent molecules of crystallization. All MCl(2)tripbipy complexes are four coordinate and contain distorted tetrahedral metal centers. CuCl(2)tripbipy shows a pseudo Jahn-Teller distortion, and X-band electron paramagnetic resonance (EPR) in a toluene glass gives approximate g( perpendicular, parallel) values of 2.2 and 2.1. Magnetic measurements (M = Fe, Co, Ni, Cu) are consistent with high spin d(n) configurations (n = 6-9, S = 2, 3/2, 1, 1/2) tetrahedral complexes and give chi(M)T values at 300 K of 3.56, 2.10, 1.01, and 0.37 cm(3) M(-1) K, respectively.

  7. Validation of missed space-group symmetry in X-ray powder diffraction structures with dispersion-corrected density functional theory.

    Science.gov (United States)

    Hempler, Daniela; Schmidt, Martin U; van de Streek, Jacco

    2017-08-01

    More than 600 molecular crystal structures with correct, incorrect and uncertain space-group symmetry were energy-minimized with dispersion-corrected density functional theory (DFT-D, PBE-D3). For the purpose of determining the correct space-group symmetry the required tolerance on the atomic coordinates of all non-H atoms is established to be 0.2 Å. For 98.5% of 200 molecular crystal structures published with missed symmetry, the correct space group is identified; there are no false positives. Very small, very symmetrical molecules can end up in artificially high space groups upon energy minimization, although this is easily detected through visual inspection. If the space group of a crystal structure determined from powder diffraction data is ambiguous, energy minimization with DFT-D provides a fast and reliable method to select the correct space group.

  8. The Picard group of the moduli space of r-Spin Riemann surfaces

    DEFF Research Database (Denmark)

    Randal-Williams, Oscar

    2012-01-01

    An r-Spin Riemann surface is a Riemann surface equipped with a choice of rth root of the (co)tangent bundle. We give a careful construction of the moduli space (orbifold) of r-Spin Riemann surfaces, and explain how to establish a Madsen–Weiss theorem for it. This allows us to prove the “Mumford...... conjecture” for these moduli spaces, but more interestingly allows us to compute their algebraic Picard groups (for g≥10, or g≥9 in the 2-Spin case). We give a complete description of these Picard groups, in terms of explicitly constructed line bundles....

  9. On the structure of Selmer groups of $p$-ordinary modular forms over $\\mathbf{Z}_p$-extensions

    OpenAIRE

    Kidwell, Keenan

    2016-01-01

    We prove analogues of the major algebraic results of Greenberg-Vatsal for Selmer groups of $p$-ordinary newforms over $\\mathbf{Z}_p$-extensions which may be neither cyclotomic nor anticyclotomic, under a number of technical hypotheses, including a cotorsion assumption on the Selmer groups. The main complication which arises in our work is the possible presence of finite primes which can split completely in the $\\mathbf{Z}_p$-extension being considered, resulting in the local cohomology groups...

  10. A primer on Hilbert space theory linear spaces, topological spaces, metric spaces, normed spaces, and topological groups

    CERN Document Server

    Alabiso, Carlo

    2015-01-01

    This book is an introduction to the theory of Hilbert space, a fundamental tool for non-relativistic quantum mechanics. Linear, topological, metric, and normed spaces are all addressed in detail, in a rigorous but reader-friendly fashion. The rationale for an introduction to the theory of Hilbert space, rather than a detailed study of Hilbert space theory itself, resides in the very high mathematical difficulty of even the simplest physical case. Within an ordinary graduate course in physics there is insufficient time to cover the theory of Hilbert spaces and operators, as well as distribution theory, with sufficient mathematical rigor. Compromises must be found between full rigor and practical use of the instruments. The book is based on the author's lessons on functional analysis for graduate students in physics. It will equip the reader to approach Hilbert space and, subsequently, rigged Hilbert space, with a more practical attitude. With respect to the original lectures, the mathematical flavor in all sub...

  11. Convergent-beam electron diffraction study of incommensurately modulated crystals. Pt. 2. (3 + 1)-dimensional space groups

    International Nuclear Information System (INIS)

    Terauchi, Masami; Takahashi, Mariko; Tanaka, Michiyoshi

    1994-01-01

    The convergent-beam electron diffraction (CBED) method for determining three-dimensional space groups is extended to the determination of the (3 + 1)-dimensional space groups for one-dimensional incommensurately modulated crystals. It is clarified than an approximate dynamical extinction line appears in the CBED discs of the reflections caused by an incommensurate modulation. The extinction enables the space-group determination of the (3 + 1)-dimensional crystals or the one-dimensional incommensurately modulated crystals. An example of the dynamical extinction line is shown using an incommensurately modulated crystal of Sr 2 Nb 2 O 7 . Tables of the dynamical extinction lines appearing in CBED patterns are given for all the (3 + 1)-dimensional space groups of the incommensurately modulated crystal. (orig.)

  12. An introduction to data reduction: space-group determination, scaling and intensity statistics.

    Science.gov (United States)

    Evans, Philip R

    2011-04-01

    This paper presents an overview of how to run the CCP4 programs for data reduction (SCALA, POINTLESS and CTRUNCATE) through the CCP4 graphical interface ccp4i and points out some issues that need to be considered, together with a few examples. It covers determination of the point-group symmetry of the diffraction data (the Laue group), which is required for the subsequent scaling step, examination of systematic absences, which in many cases will allow inference of the space group, putting multiple data sets on a common indexing system when there are alternatives, the scaling step itself, which produces a large set of data-quality indicators, estimation of |F| from intensity and finally examination of intensity statistics to detect crystal pathologies such as twinning. An appendix outlines the scoring schemes used by the program POINTLESS to assign probabilities to possible Laue and space groups.

  13. Future In-Space Operations (FISO): A Working Group and Community Engagement

    Science.gov (United States)

    Thronson, Harley; Lester, Dan

    2013-01-01

    Long-duration human capabilities beyond low Earth orbit (LEO), either in support of or as an alternative to lunar surface operations, have been assessed at least since the late 1960s. Over the next few months, we will present short histories of concepts for long-duration, free-space human habitation beyond LEO from the end of the Apollo program to the Decadal Planning Team (DPT)/NASA Exploration Team (NExT), which was active in 1999 2000 (see Forging a vision: NASA s Decadal Planning Team and the origins of the Vision for Space Exploration , The Space Review, December 19, 2005). Here we summarize the brief existence of the Future In-Space Operations (FISO) working group in 2005 2006 and its successor, a telecon-based colloquium series, which we co-moderate.

  14. Space-time versus world-sheet renormalization group equation in string theory

    International Nuclear Information System (INIS)

    Brustein, R.; Roland, K.

    1991-05-01

    We discuss the relation between space-time renormalization group equation for closed string field theory and world-sheet renormalization group equation for first-quantized strings. Restricting our attention to massless states we argue that there is a one-to-one correspondence between the fixed point solutions of the two renormalization group equations. In particular, we show how to extract the Fischler-Susskind mechanism from the string field theory equation in the case of the bosonic string. (orig.)

  15. The pMSSM Interpretation of LHC Results Using Rernormalization Group Invariants

    Energy Technology Data Exchange (ETDEWEB)

    Carena, Marcela [Fermi National Accelerator Laboratory (FNAL), Batavia, IL (United States); Lykken, Joseph [Fermi National Accelerator Laboratory (FNAL), Batavia, IL (United States); Sekmen, Sezen [CERN, Geneva (Switzerland); Shah, Nausheen R. [Fermi National Accelerator Laboratory (FNAL), Batavia, IL (United States); Wagner, Carlos E.M. [Enrico Fermi Institute, Univ. of Chicago, IL (United States)

    2012-10-01

    The LHC has started to constrain supersymmetry-breaking parameters by setting bounds on possible colored particles at the weak scale. Moreover, constraints from Higgs physics, flavor physics, the anomalous magnetic moment of the muon, as well as from searches at LEP and the Tevatron have set additional bounds on these parameters. Renormalization Group Invariants (RGIs) provide a very useful way of representing the allowed parameter space by making direct connection with the values of these parameters at the messenger scale. Using a general approach, based on the pMSSM parametrization of the soft supersymmetry-breaking parameters, we analyze the current experimental constraints to determine the probability distributions for the RGIs. As examples of their application, we use these distributions to analyze the question of Gaugino Mass Unification and to probabilistically determine the parameters of General and Minimal Gauge Mediation with arbitrary Higgs mass parameters at the Messenger Scale.

  16. The pMSSM Interpretation of LHC Results Using Rernormalization Group Invariants

    CERN Document Server

    Carena, Marcela; Sekmen, Sezen; Shah, Nausheen R; Wagner, Carlos E M

    2012-01-01

    The LHC has started to constrain supersymmetry-breaking parameters by setting bounds on possible colored particles at the weak scale. Moreover, constraints from Higgs physics, flavor physics, the anomalous magnetic moment of the muon, as well as from searches at LEP and the Tevatron have set additional bounds on these parameters. Renormalization Group Invariants (RGIs) provide a very useful way of representing the allowed parameter space by making direct connection with the values of these parameters at the messenger scale. Using a general approach, based on the pMSSM parametrization of the soft supersymmetry-breaking parameters, we analyze the current experimental constraints to determine the probability distributions for the RGIs. As examples of their application, we use these distributions to analyze the question of Gaugino Mass Unification and to probabilistically determine the parameters of General and Minimal Gauge Mediation with arbitrary Higgs mass parameters at the Messenger Scale.

  17. P-R-R Study Technique, Group Counselling And Gender Influence ...

    African Journals Online (AJOL)

    Read-Recall (P-R-R) study technique and group counselling on the academic performance of senior secondary school students. The objectives of this study were to determine the effect of Group Counselling combined with P-R-R study ...

  18. Crystal structures of the free and inhibited forms of plasmepsin I (PMI) from Plasmodium falciparum.

    Science.gov (United States)

    Bhaumik, Prasenjit; Horimoto, Yasumi; Xiao, Huogen; Miura, Takuya; Hidaka, Koushi; Kiso, Yoshiaki; Wlodawer, Alexander; Yada, Rickey Y; Gustchina, Alla

    2011-07-01

    Plasmepsin I (PMI) is one of the four vacuolar pepsin-like proteases responsible for hemoglobin degradation by the malarial parasite Plasmodium falciparum, and the only one with no crystal structure reported to date. Due to substantial functional redundancy of these enzymes, lack of inhibition of even a single plasmepsin can defeat efforts in creating effective antiparasitic agents. We have now solved crystal structures of the recombinant PMI as apoenzyme and in complex with the potent peptidic inhibitor, KNI-10006, at the resolution of 2.4 and 3.1Å, respectively. The apoenzyme crystallized in the orthorhombic space group P2(1)2(1)2(1) with two molecules in the asymmetric unit and the structure has been refined to the final R-factor of 20.7%. The KNI-10006 bound enzyme crystallized in the tetragonal space group P4(3) with four molecules in the asymmetric unit and the structure has been refined to the final R-factor of 21.1%. In the PMI-KNI-10006 complex, the inhibitors were bound identically to all four enzyme molecules, with the opposite directionality of the main chain of KNI-10006 relative to the direction of the enzyme substrates. Such a mode of binding of inhibitors containing an allophenylnorstatine-dimethylthioproline insert in the P1-P1' positions, previously reported in a complex with PMIV, demonstrates the importance of satisfying the requirements for the proper positioning of the functional groups in the mechanism-based inhibitors towards the catalytic machinery of aspartic proteases, as opposed to binding driven solely by the specificity of the individual enzymes. A comparison of the structure of the PMI-KNI-10006 complex with the structures of other vacuolar plasmepsins identified the important differences between them and may help in the design of specific inhibitors targeting the individual enzymes. Published by Elsevier Inc.

  19. From spin groups and modular P1CT symmetry to covariant representations and the spin-statistics theorem

    International Nuclear Information System (INIS)

    Lorenzen, R.

    2007-03-01

    Starting from the assumption of modular P 1 CT symmetry in quantum field theory a representation of the universal covering of the Poincar'e group is constructed in terms of pairs of modular conjugations. The modular conjugations are associated with field algebras of unbounded operators localised in wedge regions. It turns out that an essential step consists in characterising the universal covering group of the Lorentz group by pairs of wedge regions, in conjunction with an analysis of its geometrical properties. In this thesis two approaches to this problem are developed in four spacetime dimensions. First a realisation of the universal covering as the quotient space over the set of pairs of wedge regions is presented. In spite of the intuitive definition, the necessary properties of a covering space are not straightforward to prove. But the geometrical properties are easy to handle. The second approach takes advantage of the well-known features of spin groups, given as subgroups of Clifford algebras. Characterising elements of spin groups by pairs of wedge regions is possible in an elegant manner. The geometrical analysis is performed by means of the results achieved in the first approach. These geometrical properties allow for constructing a representation of the universal cover of the Lorentz group in terms of pairs of modular conjugations. For this representation the derivation of the spin-statistics theorem is straightforward, and a PCT operator can be defined. Furthermore, it is possible to transfer the results to nets of field algebras in algebraic quantum field theory with ease. Many of the usual assumptions in quantum field theory like the spectrum condition or the existence of a covariant unitary representation, as well as the assumption on the quantum field to have only finitely many components, are not required. For the standard axioms, the crucial assumption of modular P 1 CT symmetry constitutes no loss of generality because it is a consequence of

  20. Description of symmetry of magnetic structures by representations of space groups. [Tables, projecton operator methods

    Energy Technology Data Exchange (ETDEWEB)

    Sikora, W

    1974-10-15

    A description of magnetic structures based on the use of representations of space groups is given. Representations of the space groups were established for each compound on the basis of experimental data by the method of projection operators. The compounds contained in the list are collected according to crystal systems, alphabetically within each system. The description of each compound consists of the four parts. The first part contain the chemical symbol of the compound, the second its space group. The next part contains the chemical symbol of the magnetic atom and its positions in Wychoff notation with the number of equivalent positions in the crystal unit cell. The main description of a compound magnetic structure is given in the fourth part. It contains: K vector defined in the reciprocal space, the representation according to which a magnetic structure is transformed and the axial vector function S which describes the magnetic structure.

  1. Mathematical aspects of molecular replacement. III. Properties of space groups preferred by proteins in the Protein Data Bank.

    Science.gov (United States)

    Chirikjian, G; Sajjadi, S; Toptygin, D; Yan, Y

    2015-03-01

    The main goal of molecular replacement in macromolecular crystallography is to find the appropriate rigid-body transformations that situate identical copies of model proteins in the crystallographic unit cell. The search for such transformations can be thought of as taking place in the coset space Γ\\G where Γ is the Sohncke group of the macromolecular crystal and G is the continuous group of rigid-body motions in Euclidean space. This paper, the third in a series, is concerned with viewing nonsymmorphic Γ in a new way. These space groups, rather than symmorphic ones, are the most common ones for protein crystals. Moreover, their properties impact the structure of the space Γ\\G. In particular, nonsymmorphic space groups contain both Bieberbach subgroups and symmorphic subgroups. A number of new theorems focusing on these subgroups are proven, and it is shown that these concepts are related to the preferences that proteins have for crystallizing in different space groups, as observed in the Protein Data Bank.

  2. Overexpression, crystallization and preliminary X-­ray crystallographic analysis of erythronate-4-phosphate dehydrogenase from Pseudomonas aeruginosa

    Science.gov (United States)

    Ha, Jun Yong; Lee, Ji Hyun; Kim, Kyoung Hoon; Kim, Do Jin; Lee, Hyung Ho; Kim, Hye-Kyung; Yoon, Hye-Jin; Suh, Se Won

    2006-01-01

    The enzyme erythronate-4-phosphate dehydrogenase catalyses the conversion of erythronate-4-phosphate to 3-hydroxy-4-phospho-hydroxy-α-ketobutyrate. It belongs to the d-isomer-specific 2-hydroxyacid dehydrogenase family. It is essential for de novo biosynthesis of vitamin B6 (pyridoxine). Erythronate-4-­phosphate dehydrogenase from Pseudomonas aeruginosa, a homodimeric enzyme consisting of two identical 380-residue subunits, has been overexpressed in Escherichia coli with a C-terminal purification tag and crystallized at 297 K using 0.7 M ammonium dihydrogen phosphate, 0.4 M ammonium tartrate, 0.1 M sodium citrate pH 5.6 and 10 mM cupric chloride. X-ray diffraction data were collected to 2.20 Å from a crystal grown in the presence of NADH. The crystals belong to the orthorhombic space group P212121, with unit-cell parameters a = 84.77, b = 101.28, c = 142.58 Å. A dimeric molecule is present in the asymmetric unit, giving a crystal volume per protein weight (V M) of 3.64 Å3 Da−1 and a solvent content of 66%. PMID:16511285

  3. Group Analysis in FieldTrip of Time-Frequency Responses: A Pipeline for Reproducibility at Every Step of Processing, Going From Individual Sensor Space Representations to an Across-Group Source Space Representation

    Directory of Open Access Journals (Sweden)

    Lau M. Andersen

    2018-05-01

    Full Text Available An important aim of an analysis pipeline for magnetoencephalographic (MEG data is that it allows for the researcher spending maximal effort on making the statistical comparisons that will answer his or her questions. The example question being answered here is whether the so-called beta rebound differs between novel and repeated stimulations. Two analyses are presented: going from individual sensor space representations to, respectively, an across-group sensor space representation and an across-group source space representation. The data analyzed are neural responses to tactile stimulations of the right index finger in a group of 20 healthy participants acquired from an Elekta Neuromag System. The processing steps covered for the first analysis are MaxFiltering the raw data, defining, preprocessing and epoching the data, cleaning the data, finding and removing independent components related to eye blinks, eye movements and heart beats, calculating participants' individual evoked responses by averaging over epoched data and subsequently removing the average response from single epochs, calculating a time-frequency representation and baselining it with non-stimulation trials and finally calculating a grand average, an across-group sensor space representation. The second analysis starts from the grand average sensor space representation and after identification of the beta rebound the neural origin is imaged using beamformer source reconstruction. This analysis covers reading in co-registered magnetic resonance images, segmenting the data, creating a volume conductor, creating a forward model, cutting out MEG data of interest in the time and frequency domains, getting Fourier transforms and estimating source activity with a beamformer model where power is expressed relative to MEG data measured during periods of non-stimulation. Finally, morphing the source estimates onto a common template and performing group-level statistics on the data are

  4. Space-charge-mediated anomalous ferroelectric switching in P(VDF-TrEE) polymer films

    KAUST Repository

    Hu, Weijin; Wang, Zhihong; Du, Yuanmin; Zhang, Xixiang; Wu, Tao

    2014-01-01

    We report on the switching dynamics of P(VDF-TrEE) copolymer devices and the realization of additional substable ferroelectric states via modulation of the coupling between polarizations and space charges. The space-charge-limited current

  5. Axiomatics of uniform space-time models

    International Nuclear Information System (INIS)

    Levichev, A.V.

    1983-01-01

    The mathematical statement of space-time axiomatics of the special theory of relativity is given; it postulates that the space-time M is the binding single boundary Hausedorf local-compact four-dimensional topological space with the given order. The theorem is proved: if the invariant order in the four-dimensional group M is given by the semi-group P, which contingency K contains inner points , then M is commutative. The analogous theorem is correct for the group of two and three dimensionalities

  6. Lie groups and symmetric spaces in memory of F. I. Karpelevich

    CERN Document Server

    Gindikin, S G

    2003-01-01

    The book contains survey and research articles devoted mainly to geometry and harmonic analysis of symmetric spaces and to corresponding aspects of group representation theory. The volume is dedicated to the memory of Russian mathematician F. I. Karpelevich (1927-2000).

  7. Group Clustering Mechanism for P2P Large Scale Data Sharing Collaboration

    Institute of Scientific and Technical Information of China (English)

    DENGQianni; LUXinda; CHENLi

    2005-01-01

    Research shows that P2P scientific collaboration network will exhibit small-world topology, as do a large number of social networks for which the same pattern has been documented. In this paper we propose a topology building protocol to benefit from the small world feature. We find that the idea of Freenet resembles the dynamic pattern of social interactions in scientific data sharing and the small world characteristic of Freenet is propitious to improve the file locating performance in scientificdata sharing. But the LRU (Least recently used) datas-tore cache replacement scheme of Freenet is not suitableto be used in scientific data sharing network. Based onthe group locality of scientific collaboration, we proposean enhanced group clustering cache replacement scheme.Simulation shows that this scheme improves the request hitratio dramatically while keeping the small average hops per successful request comparable to LRU.

  8. Radiation hardening of InP solar cells for space applications

    International Nuclear Information System (INIS)

    Vilela, M. F.; Freundlich, A.; Monier, C.; Newman, F.; Aguilar, L.

    1998-01-01

    The aim of this work is to develop a radiation resistant thin InP-based solar cells for space applications on more mechanically resistant, lighter, and cheaper substrates. In this paper, we present the development of a p + /nn + InP-based solar cell structures with very thin emitter and base layers. A thin emitter helps to increase the collection of carriers generated by high energy incident photons from the solar spectrum. The use of a thin n base structure should improve the radiation resistance of this already radiation resistant technology. A remarkable improvement of high energy photons response is shown for InP solar cells with emitters 400 A thick

  9. Validation of missed space-group symmetry in X-ray powder diffraction structures with dispersion-corrected density functional theory

    DEFF Research Database (Denmark)

    Hempler, Daniela; Schmidt, Martin U.; Van De Streek, Jacco

    2017-01-01

    More than 600 molecular crystal structures with correct, incorrect and uncertain space-group symmetry were energy-minimized with dispersion-corrected density functional theory (DFT-D, PBE-D3). For the purpose of determining the correct space-group symmetry the required tolerance on the atomic...... with missed symmetry were investigated by dispersion-corrected density functional theory. In 98.5% of the cases the correct space group is found....

  10. Crystallization and preliminary X-ray diffraction analysis of L,L-diaminopimelate aminotransferase (DapL) from Chlamydomonas reinhardtii.

    Science.gov (United States)

    Hudson, André O; Girón, Irma; Dobson, Renwick C J

    2011-01-01

    In the anabolic synthesis of diaminopimelate and lysine in plants and in some bacteria, the enzyme L,L-diaminopimelate aminotransferase (DapL; EC 2.6.1.83) catalyzes the conversion of tetrahydrodipicolinic acid (THDPA) to L,L-diaminopimelate, bypassing the DapD, DapC and DapE enzymatic steps in the bacterial acyl pathways. Here, the cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of DapL from the alga Chlamydomonas reinhardtii are presented. Protein crystals were grown in conditions containing 25% (w/v) PEG 3350 and 200 mM lithium sulfate and initially diffracted to ∼1.35 Å resolution. They belonged to space group P2(1)2(1)2(1), with unit-cell parameters a=58.9, b=91.8, c=162.9 Å. The data were processed to 1.55 Å resolution with an Rmerge of 0.081, an Rp.i.m. of 0.044, an Rr.i.m of 0.093 and a VM of 2.28 Å3 Da(-1).

  11. Winter School on Operator Spaces, Noncommutative Probability and Quantum Groups

    CERN Document Server

    2017-01-01

    Providing an introduction to current research topics in functional analysis and its applications to quantum physics, this book presents three lectures surveying recent progress and open problems.  A special focus is given to the role of symmetry in non-commutative probability, in the theory of quantum groups, and in quantum physics. The first lecture presents the close connection between distributional symmetries and independence properties. The second introduces many structures (graphs, C*-algebras, discrete groups) whose quantum symmetries are much richer than their classical symmetry groups, and describes the associated quantum symmetry groups. The last lecture shows how functional analytic and geometric ideas can be used to detect and to quantify entanglement in high dimensions.  The book will allow graduate students and young researchers to gain a better understanding of free probability, the theory of compact quantum groups, and applications of the theory of Banach spaces to quantum information. The l...

  12. International Space Station Earth Observations Working Group

    Science.gov (United States)

    Stefanov, William L.; Oikawa, Koki

    2015-01-01

    The multilateral Earth Observations Working Group (EOWG) was chartered in May 2012 in order to improve coordination and collaboration of Earth observing payloads, research, and applications on the International Space Station (ISS). The EOWG derives its authority from the ISS Program Science Forum, and a NASA representative serves as a permanent co-chair. A rotating co-chair position can be occupied by any of the international partners, following concurrence by the other partners; a JAXA representative is the current co-chair. Primary functions of the EOWG include, 1) the exchange of information on plans for payloads, from science and application objectives to instrument development, data collection, distribution and research; 2) recognition and facilitation of opportunities for international collaboration in order to optimize benefits from different instruments; and 3) provide a formal ISS Program interface for collection and application of remotely sensed data collected in response to natural disasters through the International Charter, Space and Major Disasters. Recent examples of EOWG activities include coordination of bilateral data sharing protocols between NASA and TsNIIMash for use of crew time and instruments in support of ATV5 reentry imaging activities; discussion of continued use and support of the Nightpod camera mount system by NASA and ESA; and review and revision of international partner contributions on Earth observations to the ISS Program Benefits to Humanity publication.

  13. From spin groups and modular P{sub 1}CT symmetry to covariant representations and the spin-statistics theorem

    Energy Technology Data Exchange (ETDEWEB)

    Lorenzen, R.

    2007-03-15

    Starting from the assumption of modular P{sub 1}CT symmetry in quantum field theory a representation of the universal covering of the Poincar'e group is constructed in terms of pairs of modular conjugations. The modular conjugations are associated with field algebras of unbounded operators localised in wedge regions. It turns out that an essential step consists in characterising the universal covering group of the Lorentz group by pairs of wedge regions, in conjunction with an analysis of its geometrical properties. In this thesis two approaches to this problem are developed in four spacetime dimensions. First a realisation of the universal covering as the quotient space over the set of pairs of wedge regions is presented. In spite of the intuitive definition, the necessary properties of a covering space are not straightforward to prove. But the geometrical properties are easy to handle. The second approach takes advantage of the well-known features of spin groups, given as subgroups of Clifford algebras. Characterising elements of spin groups by pairs of wedge regions is possible in an elegant manner. The geometrical analysis is performed by means of the results achieved in the first approach. These geometrical properties allow for constructing a representation of the universal cover of the Lorentz group in terms of pairs of modular conjugations. For this representation the derivation of the spin-statistics theorem is straightforward, and a PCT operator can be defined. Furthermore, it is possible to transfer the results to nets of field algebras in algebraic quantum field theory with ease. Many of the usual assumptions in quantum field theory like the spectrum condition or the existence of a covariant unitary representation, as well as the assumption on the quantum field to have only finitely many components, are not required. For the standard axioms, the crucial assumption of modular P{sub 1}CT symmetry constitutes no loss of generality because it is a

  14. An electron diffraction and bond valence sum study of the space group symmetries and structures of the photocatalytic 1:1 ordered A2InNbO6 double perovskites (A=Ca2+, Sr2+, Ba2+)

    International Nuclear Information System (INIS)

    Ting, V.; Liu, Y.; Withers, R.L.; Krausz, E.

    2004-01-01

    A careful investigation has been carried out into the space group symmetries, structures and crystal chemistries of the 1:1 B-site ordered double perovskites A 2 InNbO 6 (A=Ca 2+ , Sr 2+ , Ba 2+ ) using a combination of bond valence sum calculations, powder XRD and electron diffraction. A recent investigation of these compounds by Yin et al. reported a random distribution of In 3+ and Nb 5+ ions onto the perovskite B-site positions of these compounds and hence Pm3-barm (a=a p , subscript p for parent perovskite sub-structure) space group symmetry for the A=Ba and Sr compounds and Pnma (a=a p +b p , b=-a p +b p , c=2c p ) space group symmetry for the A=Ca compound. A careful electron diffraction study, however, shows that both the A=Ca and Sr compounds occur at room temperature in P12 1 /n1 (a=a p +b p , b=-a p +b p , c=2c p ) perovskite-related superstructure phases while the A=Ba compound occurs in the Fm3-barm, a=2a p , elpasolite structure type. Bond valence sum calculations are used to explain why this should be so as well as to provide a useful first-order approximation to the structures of each of the compounds

  15. Macdonald polynomials from Sklyanin algebras: A conceptual basis for the p-adics-quantum group connection

    International Nuclear Information System (INIS)

    Freund, P.G.O.

    1992-01-01

    We establish a previously conjectured connection between p-adics and quantum groups. We find in Sklyanin's two parameter elliptic quantum algebra and its generalizations, the conceptual basis for the Macdonald polynomials, which 'interpolate' between the zonal spherical functions of related real and p-adic symmetric spaces. The elliptic quantum algebras underlie the Z n -Baxter models. We show that in the n→∞ limit, the Jost function for the scattering of first level excitations in the Z n -Baxter model coincides with the Harish-Chandra-like c-function constructed from the Macdonald polynomials associated to the root system A 1 . The partition function of the Z 2 -Baxter model itself is also expressed in terms of this Macdonald-Harish-Chandra c-function albeit in a less simple way. We relate the two parameters q and t of the Macdonald polynomials to the anisotropy and modular parameters of the Baxter model. In particular the p-acid 'regimes' in the Macdonald polynomials correspond to a discrete sequence of XXZ models. We also discuss the possibility of 'q-deforming' Euler products. (orig.)

  16. Analytic factorization of Lie group representations

    DEFF Research Database (Denmark)

    Gimperlein, Heiko; Krötz, Bernhard; Lienau, Christoph

    2012-01-01

    For every moderate growth representation (p,E)(p,E) of a real Lie group G on a Fréchet space, we prove a factorization theorem of Dixmier–Malliavin type for the space of analytic vectors E¿E¿. There exists a natural algebra of superexponentially decreasing analytic functions A(G)A(G), such that E......¿=¿(A(G))E¿E¿=¿(A(G))E¿. As a corollary we obtain that E¿E¿ coincides with the space of analytic vectors for the Laplace–Beltrami operator on G....

  17. Polymorphism in R-tamsulosin (an alpha blocker): The unexpected manifestation of a sulfonamide⋯o-diethoxybenzene heterosynthon

    Science.gov (United States)

    Nanubolu, Jagadeesh Babu; Sridhar, Balasubramanian; Ravikumar, Krishnan

    2014-12-01

    A two point Nsbnd H⋯O dimer or an infinite catemer are the most preferred motifs/synthons for sulfonamide structures. Such synthons are known to be so robust that they are only disrupted in the presence of highly activated O acceptors such as pyridine-N-oxide and sulfoxide. We demonstrate in this article that a multi-point synthon offered by much weaker ethoxy O and amine N acceptors can however strongly compete and disrupt the robust sulfonamide homosynthons. This has been illustrated with the synthon analysis in three polymorphic crystal structures of R-tamsulosin, an active drug used in the treatment of Benign Prostatic Hyperplasia (BPH) and its hydrochloride salt. These crystalline solids are characterized by Single crystal X-ray diffraction (SC-XRD), powder X-ray diffraction (PXRD), Fourier Transform Infrared (FT-IR) and Raman spectroscopy. Forms I, II of the free base and hydrochloride salt crystallize in the monoclinic P21, C2, and P21 space groups respectively with two molecules in the asymmetric unit (Z‧ = 2), whereas, form III of freebase crystallize in the orthorhombic P212121 space group with Z‧ = 1. Remarkably, all four crystal structures contain a totally unexpected sulfonamide⋯o-diethoxybenzene heterosynthon. The multi-point motifs observed in polymorphs are relatively stronger than those in the hydrochloride salt because of the gauche conformation of the tamsulosin linker chain which renders an additional hydrogen bond interaction with amine N acceptor, and resemble the crown ether sulfonamide recognition pattern. Observation of this new heterosynthon offers potential scope in the design of pharmaceutical cocrystals for sulfonamide bearing drug molecules. The present study also presents a detailed hydrogen bond motif analysis in 310 primary sulfonamide structures culled from the latest version of Cambridge Structural Database (CSD). The role of various competing groups is discussed in the context of understanding the most recurring

  18. Numerical simulation of amplification of space charge waves in n-InP films

    International Nuclear Information System (INIS)

    Garcia-Barrientos, Abel; Palankovski, Vassil

    2011-01-01

    The non-linear interaction of space charge waves including the amplification in microwave and millimeter wave range in n-InP films, possessing the negative differential conductance phenomenon, is investigated theoretically. Both the amplified signal and the generation of harmonics of the input signal are demonstrated, which are due to non-linear effect of the negative differential resistance. It is possible to observe an amplification of the space charge waves in n-InP films of submicron thicknesses at essentially higher frequencies f <70 GHz, when compared with n-GaAs films f < 44 GHz. The increment observed in the gain is due to the larger dynamic range in n-InP than in n-GaAs films.

  19. Group quantization on configuration space: Gauge symmetries and linear fields

    International Nuclear Information System (INIS)

    Navarro, M.; Aldaya, V.; Calixto, M.

    1997-01-01

    A new, configuration-space picture of a formalism of group quantization, the GAQ formalism, is presented in the context of a previous algebraic generalization. This presentation serves to make a comprehensive discussion in which other extensions of the formalism, principally to incorporate gauge symmetries, are developed as well. Both images are combined in order to analyze, in a systematic manner and with complete generality, the case of linear fields (Abelian current groups). To illustrate these developments we particularize them for several fields and, in particular, we carry out the quantization of the Abelian Chern endash Simons models over an arbitrary closed surface in detail. copyright 1997 American Institute of Physics

  20. BAYESZ, S-Wave, P-Wave Resonance Level Spacing and Strength Functions

    International Nuclear Information System (INIS)

    Moore, M.S.

    1982-01-01

    A - Description of problem or function: BAYESZ calculates average s- and p-wave level spacings, strength functions, and average radiation widths of a mixed sequence of s- and p-wave resonances whose parameters are supplied as input. The code is based on two physical assumptions: 1) The neutron reduced width distribution for each open channel is a chi-squared distribution with one degree of freedom, i.e. Porter-Thomas. 2) The spacing distribution follows the Gaussian Orthogonal Ensemble. This property is used, however, only to fix the s- to p-wave level density ratio as proportional to (2J+1) with a spin cut-off correction. B - Method of solution: The method used is an extension of that described by Moore et al. in reference (1), and is based on the method of moments of a truncated Porter-Thomas distribution. C - Restrictions on the complexity of the problem: Parameters for a maximum of 500 individual resonances can be specified. This restriction can be relaxed by increasing array dimensions

  1. Irreducible quantum group modules with finite dimensional weight spaces

    DEFF Research Database (Denmark)

    Pedersen, Dennis Hasselstrøm

    a finitely generated U q -module which has finite dimensional weight spaces and is a sum of those. Our approach follows the procedures used by S. Fernando and O. Mathieu to solve the corresponding problem for semisimple complex Lie algebra modules. To achieve this we have to overcome a number of obstacles...... not present in the classical case. In the process we also construct twisting functors rigerously for quantum group modules, study twisted Verma modules and show that these admit a Jantzen filtration with corresponding Jantzen sum formula....

  2. [Nah-plasmids of IncP-9 group from natural strains of Pseudomonas].

    Science.gov (United States)

    Levchuk, A A; Bulyga, I M; Izmalkova, T Iu; Sevast'ianovich, Ia R; Kosheleva, I A; Thomas, C M; Titok, M A

    2006-01-01

    Use of polymerase chain reaction helped to establish that the most frequent among naphthalene utilizing bacteria, isolated on the territory of Belarus, are Nah-plasmids of IncP-9 incompatibility group and those with indefinite systematic belonging. With the help of classical test of incompatibility, restriction and sequence analyses three new subgroups within the IncP-9 group were discovered (zeta, eta and IncP-9-like replicons). Conducting of restriction analysis for amplification products of nahG and nahAc genes allowed us to reveal, in addition to known sequences of stated determinants, two new types of nahG gene. Restriction analysis performed on amplification products of 16S RNA genes (ARDRA method) showed that native hosts of Nah-plasmids of IncP-9 group are not only fluorescent bacteria from genus Pseudomonas (P. fluorescens, P. putida, P. aeruginosa, P. species), but also non-fluorescent bacteria with indefinite specific belonging.

  3. Geometry, rigidity, and group actions

    CERN Document Server

    Farb, Benson; Zimmer, Robert J

    2011-01-01

    The study of group actions is more than a hundred years old but remains to this day a vibrant and widely studied topic in a variety of mathematic fields. A central development in the last fifty years is the phenomenon of rigidity, whereby one can classify actions of certain groups, such as lattices in semi-simple Lie groups. This provides a way to classify all possible symmetries of important spaces and all spaces admitting given symmetries. Paradigmatic results can be found in the seminal work of George Mostow, Gergory Margulis, and Robert J. Zimmer, among others.The p

  4. CfDS attends the first meeting of the All-Party Parliamentary Astronomy and Space Environment Group

    Science.gov (United States)

    Mizon, B.

    1999-06-01

    This group first met on March 11th, 1999, as 'a forum for discussion to further parliamentary interest in astronomy and the space environment affecting terrestrial life and its climate; and to increase awareness of the social, political and philosophical implications of present and future space technologies connected with exploring and understanding the cosmos'. CfDS coordinator Bob Mizon attended the first meeting of the group.

  5. ESTIMA, Neutron Width Level Spacing, Neutron Strength Function of S- Wave, P-Wave Resonances

    International Nuclear Information System (INIS)

    Fort, E.

    1982-01-01

    1 - Description of problem or function: ESTIMA calculates level spacing and neutron strength function of a mixed sequence of s- and p-wave resonances given a set of neutron widths as input parameters. Three algorithms are used, two of which calculate s-wave average parameters and assume that the reduced widths obey a Porter-Thomas distribution truncated by a minimum detection threshold. The third performs a maximum likelihood fit to a truncated chi-squared distribution of any specified number of degrees of freedom, i.e. it can be used for calculating s-wave or p-wave average parameters. Resonances of undeclared angular orbital momentum are divided into groups of probable s-wave and probable p-wave by a simple application of Bayes' Theorem. 2 - Method of solution: Three algorithms are used: i) GAMN method, based on simple moments properties of a Porter-Thomas distribution. ii) Missing Level Estimator, a simplified version of the algorithm used by the program BAYESZ. iii) ESTIMA, a maximum likelihood fit. 3 - Restrictions on the complexity of the problem: A maximum of 400 resonances is allowed in the version available from NEADB, however this restriction can be relaxed by increasing array dimensions

  6. The dual algebra of the Poincare group on Fock space

    International Nuclear Information System (INIS)

    Klink, W.H.; Iowa Univ., Iowa City, IA

    1989-01-01

    The Lie algebra of operators commuting with the Poincare group on the Fock space appropriate for a massive spinless particle is constructed in terms of raising and lowering operators indexed by a Lorentz invariant function. From the assumption that the phase operator is an element of this Lie algebra, it is shown that the scattering operator can be written as a unitary representation operator of the group associated with the Lie algebra. A simple choice of the phase operator shows that the Lorentz invariant function can be interpreted as a basic scattering amplitude, in the sense that all multiparticle scattering amplitudes can be written in terms of this basic scattering amplitude. (orig.)

  7. Real space renormalization group for spectra and density of states

    International Nuclear Information System (INIS)

    Wiecko, C.; Roman, E.

    1984-09-01

    We discuss the implementation of the Real Space Renormalization Group Decimation Technique for 1-d tight-binding models with long range interactions with or without disorder and for the 2-d regular square lattice. The procedure follows the ideas developed by Southern et al. Some new explicit formulae are included. The purpose of this study is to calculate spectra and densities of states following the procedure developed in our previous work. (author)

  8. Evaluation of the effects of subgingival injection of Simvastatin on space re-opening after orthodontic space closure in adults.

    Science.gov (United States)

    Jahanbin, Arezoo; Abtahi, Mostafa; Namdar, Parastoo; Heravi, Farzin; Sadeghi, Fatemeh; Arab, Hamidreza; Shafaee, Hooman

    2016-01-01

    Background. This clinical trial evaluated the effect of Simvastatin on space re-opening after orthodontic space closure and its effect on the gingival index (GI) and clinical attachment loss (CAL). Methods. 16 females, 25-40 years old, with spaces between anterior mandibular teeth due to chronic periodontitis were participated in this study. The patients were randomly divided into control and experimental groups. In the experimental group, 1.2% Simvastatin gel and in the control group, 0.9% sodium chloride as a placebo was injected into the pocket depth of the six anterior teeth. The amount of space reopening, GI and CAL were measured. Results. No serious complications were observed during interventions and follow-up periods. Space re-opening was significantly reduced in patients receiving Simvastatin (P space re-opening after orthodontic space closure in human anterior teeth.

  9. El Naschie's Cantorian space-time and general relativity by means of Barbilian's group. A Cantorian fractal axiomatic model of space-time

    International Nuclear Information System (INIS)

    Gottlieb, I.; Agop, M.; Jarcau, M.

    2004-01-01

    One builds the vacuum metrics of the stationary electromagnetic field through the complex potential model. There are thus emphasized both a variational principle, independent on the Ricci tensor, and some internal symmetries of the vacuum solutions. One shows that similar results may be obtained using the Barbiliant's group. By analytical continuation of a Barbilian transformation the link between the fixed points of the modular groups of the vacuum and the golden mean PHI=(1/(1+PHI))=(√5-1)/2 of ε (∞) space-time is established. Finally, a Cantorian fractal axiomatic model of the space-time is presented. The model is explained using a set of coupled equations which may describe the self organizing processes at the solid-liquid, plasma-plasma, and superconductor-superconductor interfaces

  10. Synthesis and studies on structural, optical and nonlinear optical properties of novel organic inter-molecular compounds: 4-chloro-3-nitroaniline-3-hydroxy benzaldehyde and urea-4-dimethylaminopyridine

    Science.gov (United States)

    Pandey, Priyanka; Rai, R. N.

    2018-05-01

    Two novel organic inter-molecular compounds (IMCs), (3-(4-chloro-3-nitrophenylimino) methyl) phenol) (CNMP) and urea ̶ 4-dimethylaminopyridine complex (UDMAP), have been synthesized by solid state reaction. These two IMCs were identified by phase diagram study of CNA-HB and U-DMAP systems. The single crystals of newly obtained IMCs were grown by slow solvent evaporation technique at room temperature. Both the IMCs were further studied for their thermal, spectral, single crystal XRD for their atomic packing in molecule, crystallinity, optical and nonlinear optical behaviour. In both the cases, melting point of inter-molecular compounds was found to be higher than that of their parent components, CNMP was found to be thermally stable up to 158 °C while UDMAP was stable up to 144 °C, which indicate their extra stability than their parents. The single crystal XRD studies confirmed that CNMP has crystallized in orthorhombic unit cell with non-centrosymmetric space group P212121 while UDMAP has crystallized in monoclinic unit cell with centrosymmetric space group C2/c. The absorption spectrum of CNMP was found to be in between the absorption of parents, while broadening of peak and red shift was observed in UDMAP as compared to the parents. Second order nonlinear optical property of CNMP and UDMAP was studied using Kurtz Perry powder technique and intense green light emission was observed with CNMP on excitation with 1064 nm of Nd:YAG laser while no emission was observed with UDMAP.

  11. Lack of adaptation to human tetherin in HIV-1 Group O and P

    Science.gov (United States)

    2011-01-01

    Background HIV-1 viruses are categorized into four distinct groups: M, N, O and P. Despite the same genomic organization, only the group M viruses are responsible for the world-wide pandemic of AIDS, suggesting better adaptation to human hosts. Previously, it has been reported that the group M Vpu protein is capable of both down-modulating CD4 and counteracting BST-2/tetherin restriction, while the group O Vpu cannot antagonize tetherin. This led us to investigate if group O, and the related group P viruses, possess functional anti-tetherin activities in Vpu or another viral protein, and to further map the residues required for group M Vpu to counteract human tetherin. Results We found a lack of activity against human tetherin for both the Vpu and Nef proteins from group O and P viruses. Furthermore, we found no evidence of anti-human tetherin activity in a fully infectious group O proviral clone, ruling out the possibility of an alternative anti-tetherin factor in this virus. Interestingly, an activity against primate tetherins was retained in the Nef proteins from both a group O and a group P virus. By making chimeras between a functional group M and non-functional group O Vpu protein, we were able to map the first 18 amino acids of group M Vpu as playing an essential role in the ability of the protein to antagonize human tetherin. We further demonstrated the importance of residue alanine-18 for the group M Vpu activity. This residue lies on a diagonal face of conserved alanines in the TM domain of the protein, and is necessary for specific Vpu-tetherin interactions. Conclusions The absence of human specific anti-tetherin activities in HIV-1 group O and P suggests a failure of these viruses to adapt to human hosts, which may have limited their spread. PMID:21955466

  12. Lack of adaptation to human tetherin in HIV-1 Group O and P

    Directory of Open Access Journals (Sweden)

    Haworth Kevin G

    2011-09-01

    Full Text Available Abstract Background HIV-1 viruses are categorized into four distinct groups: M, N, O and P. Despite the same genomic organization, only the group M viruses are responsible for the world-wide pandemic of AIDS, suggesting better adaptation to human hosts. Previously, it has been reported that the group M Vpu protein is capable of both down-modulating CD4 and counteracting BST-2/tetherin restriction, while the group O Vpu cannot antagonize tetherin. This led us to investigate if group O, and the related group P viruses, possess functional anti-tetherin activities in Vpu or another viral protein, and to further map the residues required for group M Vpu to counteract human tetherin. Results We found a lack of activity against human tetherin for both the Vpu and Nef proteins from group O and P viruses. Furthermore, we found no evidence of anti-human tetherin activity in a fully infectious group O proviral clone, ruling out the possibility of an alternative anti-tetherin factor in this virus. Interestingly, an activity against primate tetherins was retained in the Nef proteins from both a group O and a group P virus. By making chimeras between a functional group M and non-functional group O Vpu protein, we were able to map the first 18 amino acids of group M Vpu as playing an essential role in the ability of the protein to antagonize human tetherin. We further demonstrated the importance of residue alanine-18 for the group M Vpu activity. This residue lies on a diagonal face of conserved alanines in the TM domain of the protein, and is necessary for specific Vpu-tetherin interactions. Conclusions The absence of human specific anti-tetherin activities in HIV-1 group O and P suggests a failure of these viruses to adapt to human hosts, which may have limited their spread.

  13. Dipicolinate salt of imidazole: Discovering its structure and properties using different experimental methodologies and quantum chemical investigations

    Science.gov (United States)

    Thirumurugan, R.; Anitha, K.

    2018-03-01

    A novel organic proton transfer complex of imidazolium dipicolinate (ID) has been synthesized and it was grown as single crystals using slow evaporation method. The molecular structure of synthesized compound and vibrational modes of its functional groups were confirmed by (1H and 13C) NMR, FTIR and FT-Raman spectroscopic studies, respectively. Single crystal X-ray diffraction (SCXRD) analysis confirmed the orthorhombic system with noncentrosymmetric (NCS), P212121, space group of grown ID crystal. UV-Vis-NIR spectral study confirmed its high optical transparency within the region of 285-1500 nm. Powder second harmonic generation (SHG) efficiency of ID crystal was confirmed and it was 6.8 times that of KDP crystal. TG-DTA and DSC analysis revealed the higher thermal stability of grown crystal as 249 °C. The dielectric response and mechanical behaviour of grown crystal were studied effectively. Density functional theory calculations were performed to probe the relationship between the structure and its properties including molecular optimization, Mulliken atomic charge distribution, frontier molecular orbital (FMOs) and molecular electrostatic potential map (MEP) analysis and first hyperpolarizability. All these experimental and computational results were discussed in this communication and it endorsed the ID compound as a potential NLO candidate could be employed in optoelectronics device applications in near future.

  14. Grouped fuzzy SVM with EM-based partition of sample space for clustered microcalcification detection.

    Science.gov (United States)

    Wang, Huiya; Feng, Jun; Wang, Hongyu

    2017-07-20

    Detection of clustered microcalcification (MC) from mammograms plays essential roles in computer-aided diagnosis for early stage breast cancer. To tackle problems associated with the diversity of data structures of MC lesions and the variability of normal breast tissues, multi-pattern sample space learning is required. In this paper, a novel grouped fuzzy Support Vector Machine (SVM) algorithm with sample space partition based on Expectation-Maximization (EM) (called G-FSVM) is proposed for clustered MC detection. The diversified pattern of training data is partitioned into several groups based on EM algorithm. Then a series of fuzzy SVM are integrated for classification with each group of samples from the MC lesions and normal breast tissues. From DDSM database, a total of 1,064 suspicious regions are selected from 239 mammography, and the measurement of Accuracy, True Positive Rate (TPR), False Positive Rate (FPR) and EVL = TPR* 1-FPR are 0.82, 0.78, 0.14 and 0.72, respectively. The proposed method incorporates the merits of fuzzy SVM and multi-pattern sample space learning, decomposing the MC detection problem into serial simple two-class classification. Experimental results from synthetic data and DDSM database demonstrate that our integrated classification framework reduces the false positive rate significantly while maintaining the true positive rate.

  15. The bicovariant differential calculus on the κ-Poincare group and on the κ-Minkowski space

    International Nuclear Information System (INIS)

    Kosinski, P.; Maslanka, P.; Sobczyk, J.

    1996-01-01

    The bicovariant differential calculus on the four-dimensional κ-Poincare group and the corresponding Lie-algebra-like structure are described. The differential calculus on the n-dimensional κ-Minkowski space covariant under the action of the κ-Poincare group was constructed. 5 refs

  16. Extended system of space-time coordinates and generalized translation group of transformations

    International Nuclear Information System (INIS)

    Yamaleev, R.M.

    1980-01-01

    A method of extending space-time is considered. In the nonrelativistic case extending goes by joining a scalar to the 3-dimensional radius-vector, completing this to a quaternion. The interpretation of scalar obtained as a parameter of scale transfornation of the generalized translation of group of transformations is given. Some basic expressions of nonrelativistic classical mechanics in the quaternion representation are given. In the relativistic case space-time is constructed from two quaternions: the first one consists of a pair scalar-3-dimensional radius-vector; the second one, of a pair-time-scalar-3-dimensional time-vector. Time and space coordinates, enter into the expression with the opposite signature. The introduction of a time-vector as well as of a new scalar is stipulated by the requirement of the principle of conforming quantum mechanics of the 1/2 spin to classical mechanics [ru

  17. Kinematic algebras, groups for elementary particles, and the geometry of momentum space

    International Nuclear Information System (INIS)

    Izmest'ev, A.A.

    1986-01-01

    It is shown that to each n-dimensional (n≥2) homogeneous isotropic Riemannian momentum (coordinate) space there corresponds a definite kinematic local algebra of operators N/sub a/, M/sub a//sub b/, P/sub a//sub ,/ ω(a,b = 1,2,...,n). In the three-dimensional case this gives the possibility of classifying particles in accordance with the algebras of the types of momentum space. The approach developed also makes it possible to obtain generalized equations describing particles of the different types. The operators under consideration satisfy not only the relevant algebra but also relations independent of the algebra that coincide in form with the Maxwell equations

  18. Canonical Groups for Quantization on the Two-Dimensional Sphere and One-Dimensional Complex Projective Space

    International Nuclear Information System (INIS)

    Sumadi A H A; H, Zainuddin

    2014-01-01

    Using Isham's group-theoretic quantization scheme, we construct the canonical groups of the systems on the two-dimensional sphere and one-dimensional complex projective space, which are homeomorphic. In the first case, we take SO(3) as the natural canonical Lie group of rotations of the two-sphere and find all the possible Hamiltonian vector fields, and followed by verifying the commutator and Poisson bracket algebra correspondences with the Lie algebra of the group. In the second case, the same technique is resumed to define the Lie group, in this case SU (2), of CP'.We show that one can simply use a coordinate transformation from S 2 to CP 1 to obtain all the Hamiltonian vector fields of CP 1 . We explicitly show that the Lie algebra structures of both canonical groups are locally homomorphic. On the other hand, globally their corresponding canonical groups are acting on different geometries, the latter of which is almost complex. Thus the canonical group for CP 1 is the double-covering group of SO(3), namely SU(2). The relevance of the proposed formalism is to understand the idea of CP 1 as a space of where the qubit lives which is known as a Bloch sphere

  19. Space Weather Activities of IONOLAB Group: IONOLAB-TEC

    Science.gov (United States)

    Arikan, F.; Sezen, U.; Arikan, O.; Ugurlu, O.; Nayir, H.

    2009-04-01

    Space Weather (SW) is the concept of changing environmental conditions in outer space and affect Earth and its technological systems. SW is a consequence of the solar activities and the coupling of solar energy on Earth's atmosphere due to the Earth's magnetic field. The monitoring and prediction of SW has utmost importance for HF communication, Satellite communication, navigation and guidance systems, Low Earth Orbit (LEO) satellite systems, Space Craft exit and entry into the atmosphere. Ionosphere is the plasma layer of the atmosphere that is ionized by solar radiation and it is a key player of SW. Ionosphere is a temporally and spatially varying, dispersive, anisotropic and inhomogeneous medium that is characterized primarily by its electron density distribution. IONOLAB is a group of researchers of various disciplines, getting together to handle challenges of the Earth's ionosphere. The team has researchers from Hacettepe University and Bilkent University, Department of Electrical and Electronics Engineering and General Command of Mapping of Turkish Army. One of the most important contributions of IONOLAB group is the automated web-based computation service for Total Electron Content (TEC). TEC corresponds to the line integral of electron density distribution on a given path. TEC can also be expressed as the amount of free electrons within 1 m2 cross-sectional area of the cylinder on the ray path. Global Position System (GPS) provides a cost-effective medium for monitoring of ionosphere using the signals recorded by stationary GPS receivers in estimating TEC. IONOLAB group has developed IONOLAB-TEC for reliable and robust estimates for all latitudes and both calm and disturbed days by using RINEX, IONEX and satellite ephemeris data provided from the IGS centers. IONOLAB-TEC consists of a regularized signal estimation algorithm which combines signals from all GPS satellites for a given instant and a given receiver, for a desired time period or for 24 hours

  20. Realization of vector fields for quantum groups as pseudodifferential operators on quantum spaces

    International Nuclear Information System (INIS)

    Chu, Chong-Sun; Zumino, B.

    1995-01-01

    The vector fields of the quantum Lie algebra are described for the quantum groups GL q (n), SL q (N) and SO q (N) as pseudodifferential operators on the linear quantum spaces covariant under the corresponding quantum group. Their expressions are simple and compact. It is pointed out that these vector fields satisfy certain characteristic polynomial identities. The real forms SU q (N) and SO q (N,R) are discussed in detail

  1. Update of PHOENIX-P 42 group library from CENDL-2

    International Nuclear Information System (INIS)

    Zhang Baocheng

    1998-01-01

    PHOENIX-P is a lattice physics code system, developed by the Westinghouse Electric Corporation (WEC), which was transplanted and used at Dayabay Nuclear Power Plant (DNPJVC). The associated multi-group (42-group) library was derived from the evaluated nuclear data of ENDF/B-5. Since the original library is from the old evaluated nuclear data, it can not meet all the requirements of reactor physics calculations of the nuclear power plant. So it is necessary to update the library with the latest version of evaluated nuclear data. To do so, based on the investigation of the old library and the information about the library, some programs were developed at China Nuclear Data Center (CNDC) to produce PHOENIX-P format data sets mainly from CENDL-2 and the new data were used to supersede the old ones of the PHOENIX-P library

  2. Assessment of space plasma effectsfor satellite applications:Working Group 2 overview

    Directory of Open Access Journals (Sweden)

    N. Jakowski

    2004-06-01

    Full Text Available An important part of the tasks of Working Group 2 of the COST Action 271 «Assessment of space plasma effect for satellites applications» is the assessment of novel data sources for information about the state of ionisation of the ionosphere. This report deals with those aspects which are not represented adequately in the scientific papers in this issue. Here emphasis is given to the product aspect (data and model collections, descriptions of methods and algorithms, availability of products, expected future developments and the links between the past COST Actions 238 and 251 with the present Action 271 and with possible future cooperations. Working Group 2 was leading in the transionospheric propagation aspects of possible products for the International Telecommunication Union?s Radiocommunication (ITU-R Study Group 3. This report gives a short overview emphasizing future developments.

  3. Expanding P450 catalytic reaction space through evolution and engineering

    Science.gov (United States)

    McIntosh, John A.; Farwell, Christopher C.; Arnold, Frances H.

    2014-01-01

    Advances in protein and metabolic engineering have led to wider use of enzymes to synthesize important molecules. However, many desirable transformations are not catalyzed by any known enzyme, driving interest in understanding how new enzymes can be created. The cytochrome P450 enzyme family, whose members participate in xenobiotic metabolism and natural products biosynthesis, catalyzes an impressive range of difficult chemical reactions that continues to grow as new enzymes are characterized. Recent work has revealed that P450-derived enzymes can also catalyze useful reactions previously accessible only to synthetic chemistry. The evolution and engineering of these enzymes provides an excellent case study for how to genetically encode new chemistry and expand biology’s reaction space. PMID:24658056

  4. Fourier-space TEM reconstructions with symmetry adapted functions for all rotational point groups.

    Science.gov (United States)

    Trapani, Stefano; Navaza, Jorge

    2013-05-01

    A general-purpose and simple expression for the coefficients of symmetry adapted functions referred to conveniently oriented symmetry axes is given for all rotational point groups. The expression involves the computation of reduced Wigner-matrix elements corresponding to an angle specific to each group and has the computational advantage of leading to Fourier-space TEM (transmission electron microscopy) reconstruction procedures involving only real valued unknowns. Using this expression, a protocol for ab initio view and center assignment and reconstruction so far used for icosahedral particles has been tested with experimental data in other point groups. Copyright © 2013 Elsevier Inc. All rights reserved.

  5. The Community-based Organizations Working Group of the Space Science Education Support Network

    Science.gov (United States)

    Lutz, J. H.; Lowes, L. L.; Asplund, S.

    2004-12-01

    The NASA Space Science Support Network Community-based Organizations Working Group (CBOWG) has been working for the past two years on issues surrounding afterschool programs and programs for youth (e.g., Girl Scouts, Boy Scouts, Boys and Girls Clubs, 4-H, summer camps, afterschool and weekend programs for various ages, programs with emphases on minority youth). In this session the co-leaders of the CBOWG will discuss the challenges of working with community-based organizations on a regional or national level. We will highlight some ties that we have forged with the National Institute for Out of School Time (NIOST) and the National Afterschool Association (NAA). We will also talk about efforts to coordinate how various entities within NASA cooperate with community-based organizations to serve the best interests of these groups. We will give a couple of examples of how NASA space science organizations have partnered with community-based organizations. The session will include some handouts of information and resources that the CBOWG has found useful in developing an understanding of this segment of informal education groups. We would like to thank NASA for providing resources to support the work of the CBOWG.

  6. Quantitative in vivo HR-pQCT imaging of 3D wrist and metacarpophalangeal joint space width in rheumatoid arthritis.

    Science.gov (United States)

    Burghardt, Andrew J; Lee, Chan Hee; Kuo, Daniel; Majumdar, Sharmila; Imboden, John B; Link, Thomas M; Li, Xiaojuan

    2013-12-01

    In this technique development study, high-resolution peripheral quantitative computed tomography (HR-pQCT) was applied to non-invasively image and quantify 3D joint space morphology of the wrist and metacarpophalangeal (MCP) joints of patients with rheumatoid arthritis (RA). HR-pQCT imaging (82 μm voxel-size) of the dominant hand was performed in patients with diagnosed rheumatoid arthritis (RA, N = 16, age: 52.6 ± 12.8) and healthy controls (CTRL, N = 7, age: 50.1 ± 15.0). An automated computer algorithm was developed to segment wrist and MCP joint spaces. The 3D distance transformation method was applied to spatially map joint space width, and summarized by the mean joint space width (JSW), minimal and maximal JSW (JSW.MIN, JSW.MAX), asymmetry (JSW.AS), and distribution (JSW.SD)-a measure of joint space heterogeneity. In vivo precision was determined for each measure by calculating the smallest detectable difference (SDD) and root mean square coefficient of variation (RMSCV%) of repeat scans. Qualitatively, HR-pQCT images and pseudo-color JSW maps showed global joint space narrowing, as well as regional and focal abnormalities in RA patients. In patients with radiographic JSN at an MCP, JSW.SD was two-fold greater vs. CTRL (p 3D joint space morphology from HR-pQCT, could improve early detection of joint damage in rheumatological diseases.

  7. Lipovitellin-phosvitin crystals with orthorhombic features: thin-section electron microscopy, gel electrophoresis, and microanalysis in teleost and amphibian yolk platelets and a comparison with other vertebrates

    International Nuclear Information System (INIS)

    Lange, R.H.; Richter, H.P.; Riehl, R.; Zierold, K.; Trandaburu, T.; Magdowski, G.

    1983-01-01

    Yolk-platelet crystals in the teleosts Pelvicachromis pulcher and Noemacheilus barbatulus and the amphibians Xenopus laevis, Rana temporaria, R. esculenta, and Triturus sp. have been studied by electron diffraction and imaging using a standardized processing (glutaraldehyde-osmium tetroxide fixation, glutaraldehyde-urea embedding, thin-section staining), by X-ray microanalysis, and sodium dodecyl sulfate-polyacrylamide gel electrophoresis of their constituents. The crystal lattice is orthorhombic having. Crystal images in the three axial projections point to the presence of space group P212121 (or an approximation of it since the lipovitellin dimers cannot be fully equivalent in some cases), to differences between the phosvitins of the two teleosts, and to a highly unusual stain exclusion from large crystal constituents interpreted as representing lipovitellin dimers. Microanalysis in ultrathin cryosections and other preparations revealed K and Cl to be the prominent ions in the crystals (and in the superficial layer of the platelet). Gel electrophoresis (including data of cyclostomes) showed considerable molecular variations despite a closely similar crystal architecture, emphasizing a physiological significance of the architecture, which may have remained conserved for nearly 400 million years according to paleontologic views

  8. Synthesis and Characterization of Rh-Co Butterfly Clusters Capped by Functionally Substituted 1-Alkynes

    Institute of Scientific and Technical Information of China (English)

    朱保华; 胡斌; 张伟强; 边治国; 赵全义; 殷元骐; 孙杰

    2003-01-01

    By the reactions of [Rh2Co2(CO)12] 1 with functionally substituted alkyne ligands HC≡CR 2 (R = FeCp2) and 3 (R = 2-OH-C6H4COOCH2), respectively in n-hexane at room temperature, two new cluster derivatives [Rh2Co2(CO)6(μ-CO)4(μ4, η2-HC≡CR)] 4 (R = FeCp2) and 5 (R = 2-OH-C6H4COOCH2) were obtained respectively. The alkyne was inserted into the Co-Co bond of cluster 1 to give two butterfly clusters. Cluster 4 has been determined by single-crystal X-ray diffraction. Crystallographic data: C22H10Co2FeO10Rh2, Mr = 813.83, orthorhombic, space group P212121, a = 11.5318(7), b = 12.6572(7), c = 17.018(1) A。, V = 2483.9(3) A。3, Z = 4, Dc = 2.176 g/cm3, F(000) = 1568, μ = 3.233 mm-1, the final R = 0.0366 and wR = 0.0899 for 5367 observed reflections with I > 2σ(I). The two clusters have also been characterized by elemental analysis, IR and 1H-NMR spectroscopy.

  9. Comparison of the Cc and R3c space groups for the superlattice phase of Pb(Zr0.52Ti0.48)O3

    International Nuclear Information System (INIS)

    Ranjan, Rajeev; Singh, Akhilesh Kumar; Ragini; Pandey, Dhananjai

    2005-01-01

    Recent controversy about the space group of the low temperature superlattice phase of Pb(Zr 0.52 Ti 0.48 )O 3 is settled. It is shown that the R3c space group for the superlattice phase cannot correctly account for the peak positions of the superlattice reflections present in the neutron diffraction patterns. The correct space group is reconfirmed to be Cc. A comparison of the atomic coordinates of Cc and Cm space groups is also presented to show that in the absence of superlattice reflections, as is the case with x-ray diffraction data, one would land up in the Cm space group. This superlattice phase is found to coexist with another monoclinic phase of the Cm space group

  10. Synthesis, Crystal Structures, and DFT Calculations of Three New Cyano(phenylsulfonylindoles and a Key Synthetic Precursor Compound

    Directory of Open Access Journals (Sweden)

    William L. Montgomery

    2015-09-01

    Full Text Available Three cyano-1-(phenylsulfonylindole derivatives, 3-cyano-1-(phenylsulfonyl indole, (I, 2-cyano-1-(phenylsulfonylindole, (II, and 2,3-dicyano-1-(phenylsulfonyl indole, (III, and a key synthetic precursor 1-(phenylsulfonyl-1-(1,1-dimethylethyl indole-3-carboxamide, (IV, have been synthesized and their structures determined by single crystal X-ray crystallography. (I, C15H10N2O2S, is orthorhombic with space group P 212121 and cell constants: a = 4.9459(3 Å, b = 10.5401(7 Å, c = 25.0813(14 Å, V = 1307.50(14 Å3 and Z = 4. (II, C15H10N2O2S, is monoclinic with space group C 2/c and cell constants: a = 18.062(2 Å, b = 11.293(2 Å, c = 15.922(3 Å, α = 90°, β = 124.49(2°, g = 90°, V = 2676.7 Å3 and Z = 8. (III, C16H9N3O2S, is triclinic with space group P-1 and cell constants: a = 8.1986(8 Å, b = 9.6381(11 Å, c = 9.8113(5 Å, α = 95.053(6°, β = 101.441(6°, g = 108.071(9°, V = 713.02(11 Å3 and Z = 2. (IV, C19H20N2O3S, is orthorhombic with space group P ccn and cell constants: a = 13.7605(8 Å, b = 27.3177(14 Å, c = 9.7584(6 Å, α = 90°, β = 90°, g =90°, V = 3668.2(4 Å3 and Z = 8. All four compounds have the same indole nitrogen phenylsulfonyl substituent and (I, (II, and (III are nitrile derivatives. (IV is a tert-butylamide. In the crystals, the dihedral angle between the mean planes of the indole and phenylsulfonyl groups are 85.4(2° (I, 87.2(7° (II, 75.1(7° (III, and 88.6(2° (IV, respectively. Additionally, DFT geometry-optimized molecular orbital calculations were performed and frontier molecular orbitals of each compound are displayed. Correlation between the calculated molecular orbital energies (eV for the surfaces of the frontier molecular orbitals to the electronic excitation transitions from the absorption spectra of each compound has been proposed.

  11. Harmonic analysis and global solvability of a differential operator invariant on motion groups and semi-simple Lie groups

    International Nuclear Information System (INIS)

    El-Hussein, K.

    1991-08-01

    Let V be a real finite dimensional vector space and let K be a connected compact Lie group, which acts on V by means of a continuous linear representation ρ. Let G=V x p K be the motion group which is the semi-direct product of V by K and let P be an invariant differential operator on G. In this paper we give a necessary and sufficient condition for the global solvability of P on G. Now let G be a connected semi-simple Lie group with finite centre and let P be an invariant differential operator on G. We give also a necessary and sufficient condition for the global solvability of P on G. (author). 8 refs

  12. Implementation of small group discussion as a teaching method in earth and space science subject

    Science.gov (United States)

    Aryani, N. P.; Supriyadi

    2018-03-01

    In Physics Department Universitas Negeri Semarang, Earth and Space Science subject is included in the curriculum of the third year of physics education students. There are various models of teaching earth and space science subject such as textbook method, lecturer, demonstrations, study tours, problem-solving method, etc. Lectures method is the most commonly used of teaching earth and space science subject. The disadvantage of this method is the lack of two ways interaction between lecturers and students. This research used small group discussion as a teaching method in Earth and Space science. The purpose of this study is to identify the conditions under which an efficient discussion may be initiated and maintained while students are investigating properties of earth and space science subjects. The results of this research show that there is an increase in student’s understanding of earth and space science subject proven through the evaluation results. In addition, during the learning process, student’s activeness also increase.

  13. Positive-definite functions and unitary representations of locally compact groups in a Hilbert space

    International Nuclear Information System (INIS)

    Gali, I.M.; Okb el-Bab, A.S.; Hassan, H.M.

    1977-08-01

    It is proved that the necessary and sufficient condition for the existence of an integral representation of a group of unitary operators in a Hilbert space is that it is positive-definite and continuous in some topology

  14. Characterization of the automorphisms having the lifting property in the category of abelian p-groups

    Directory of Open Access Journals (Sweden)

    H. Essannouni

    2003-12-01

    Full Text Available Let p be a prime. It is shown that an automorphism α of an abelian p-group A lifts to any abelian p-group of which A is a homomorphic image if and only if α=π idA, with π an invertible p-adic integer. It is also shown that if A is torsion group or torsion-free p-divisible group, then idA and −idA are the only automorphisms of A which possess the lifting property in the category of abelian groups.

  15. Rhodium-Catalyzed Insertion Reaction of PhP Group of Pentaphenylcyclopentaphosphine with Acyclic and Cyclic Disulfides.

    Science.gov (United States)

    Arisawa, Mieko; Sawahata, Kyosuke; Yamada, Tomoki; Sarkar, Debayan; Yamaguchi, Masahiko

    2018-02-16

    Organophosphorus compounds with a phosphorus atom attached to a phenyl group and two organothio/organoseleno groups were synthesized using the rhodium-catalyzed insertion reaction of the PhP group of pentaphenylcyclopentaphosphine (PhP) 5 with acyclic disulfides and diselenides. The method was applied to the synthesis of heterocyclic compounds containing the S-P-S group by the reaction of (PhP) 5 and cyclic disulfides such as 1,2-dithietes, 1,2-dithiocane, 1,4,5-dithiopane, and 1,2-dithiolanes.

  16. Developing hybrid approaches to predict pKa values of ionizable groups

    Science.gov (United States)

    Witham, Shawn; Talley, Kemper; Wang, Lin; Zhang, Zhe; Sarkar, Subhra; Gao, Daquan; Yang, Wei

    2011-01-01

    Accurate predictions of pKa values of titratable groups require taking into account all relevant processes associated with the ionization/deionization. Frequently, however, the ionization does not involve significant structural changes and the dominating effects are purely electrostatic in origin allowing accurate predictions to be made based on the electrostatic energy difference between ionized and neutral forms alone using a static structure. On another hand, if the change of the charge state is accompanied by a structural reorganization of the target protein, then the relevant conformational changes have to be taken into account in the pKa calculations. Here we report a hybrid approach that first predicts the titratable groups, which ionization is expected to cause conformational changes, termed “problematic” residues, then applies a special protocol on them, while the rest of the pKa’s are predicted with rigid backbone approach as implemented in multi-conformation continuum electrostatics (MCCE) method. The backbone representative conformations for “problematic” groups are generated with either molecular dynamics simulations with charged and uncharged amino acid or with ab-initio local segment modeling. The corresponding ensembles are then used to calculate the pKa of the “problematic” residues and then the results are averaged. PMID:21744395

  17. Self-affine scaling from non-integer phase-space partition in $\\pi^{+}p$ and $K^{+}p$ collisions at 250 GeV/$c$

    CERN Document Server

    Agababian, N M

    1998-01-01

    A factorial-moment analysis with real (integer and non-integer) phase space partition is applied to $\\pi^+$p and K$^+$p collisions at 250 GeV/$c$. Clear evidence is shown for self-affine rather than self-similar power-law scaling in multiparticle production. The three-dimensional self-affine second-order scaling exponent is determined to be 0.061$\\pm$0.010.

  18. Loop space representation of quantum general relativity and the group of loops

    International Nuclear Information System (INIS)

    Gambini, R.

    1991-01-01

    The action of the constraints of quantum general relativity on a general state in the loop representation is coded in terms of loop derivatives. These differential operators are related to the infinitesimal generators of the group of loops and generalize the area derivative first considered by Mandelstam. A new sector of solutions of the physical states space of nonperturbative quantum general relativity is found. (orig.)

  19. Generalized 2-vector spaces and general linear 2-groups

    OpenAIRE

    Elgueta, Josep

    2008-01-01

    In this paper a notion of {\\it generalized 2-vector space} is introduced which includes Kapranov and Voevodsky 2-vector spaces. Various kinds of generalized 2-vector spaces are considered and examples are given. The existence of non free generalized 2-vector spaces and of generalized 2-vector spaces which are non Karoubian (hence, non abelian) categories is discussed, and it is shown how any generalized 2-vector space can be identified with a full subcategory of an (abelian) functor category ...

  20. Distributed Model Predictive Control over Multiple Groups of Vehicles in Highway Intelligent Space for Large Scale System

    Directory of Open Access Journals (Sweden)

    Tang Xiaofeng

    2014-01-01

    Full Text Available The paper presents the three time warning distances for solving the large scale system of multiple groups of vehicles safety driving characteristics towards highway tunnel environment based on distributed model prediction control approach. Generally speaking, the system includes two parts. First, multiple vehicles are divided into multiple groups. Meanwhile, the distributed model predictive control approach is proposed to calculate the information framework of each group. Each group of optimization performance considers the local optimization and the neighboring subgroup of optimization characteristics, which could ensure the global optimization performance. Second, the three time warning distances are studied based on the basic principles used for highway intelligent space (HIS and the information framework concept is proposed according to the multiple groups of vehicles. The math model is built to avoid the chain avoidance of vehicles. The results demonstrate that the proposed highway intelligent space method could effectively ensure driving safety of multiple groups of vehicles under the environment of fog, rain, or snow.

  1. Planning and managing future space facility projects. [management by objectives and group dynamics

    Science.gov (United States)

    Sieber, J. E.; Wilhelm, J. A.; Tanner, T. A.; Helmreich, R. L.; Burgenbauch, S. F.

    1979-01-01

    To learn how ground-based personnel of a space project plan and organize their work and how such planning and organizing relate to work outcomes, longitudinal study of the management and execution of the Space Lab Mission Development Test 3 (SMD 3) was performed at NASA Ames Research Center. A view of the problems likely to arise in organizations and some methods of coping with these problems are presented as well as the conclusions and recommendations that pertain strictly to SMD 3 management. Emphasis is placed on the broader context of future space facility projects and additional problems that may be anticipated. A model of management that may be used to facilitate problem solving and communication - management by objectives (MBO) is presented. Some problems of communication and emotion management that MBO does not address directly are considered. Models for promoting mature, constructive and satisfying emotional relationships among group members are discussed.

  2. Group Analysis in MNE-Python of Evoked Responses from a Tactile Stimulation Paradigm: A Pipeline for Reproducibility at Every Step of Processing, Going from Individual Sensor Space Representations to an across-Group Source Space Representation.

    Science.gov (United States)

    Andersen, Lau M

    2018-01-01

    An important aim of an analysis pipeline for magnetoencephalographic data is that it allows for the researcher spending maximal effort on making the statistical comparisons that will answer the questions of the researcher, while in turn spending minimal effort on the intricacies and machinery of the pipeline. I here present a set of functions and scripts that allow for setting up a clear, reproducible structure for separating raw and processed data into folders and files such that minimal effort can be spend on: (1) double-checking that the right input goes into the right functions; (2) making sure that output and intermediate steps can be accessed meaningfully; (3) applying operations efficiently across groups of subjects; (4) re-processing data if changes to any intermediate step are desirable. Applying the scripts requires only general knowledge about the Python language. The data analyses are neural responses to tactile stimulations of the right index finger in a group of 20 healthy participants acquired from an Elekta Neuromag System. Two analyses are presented: going from individual sensor space representations to, respectively, an across-group sensor space representation and an across-group source space representation. The processing steps covered for the first analysis are filtering the raw data, finding events of interest in the data, epoching data, finding and removing independent components related to eye blinks and heart beats, calculating participants' individual evoked responses by averaging over epoched data and calculating a grand average sensor space representation over participants. The second analysis starts from the participants' individual evoked responses and covers: estimating noise covariance, creating a forward model, creating an inverse operator, estimating distributed source activity on the cortical surface using a minimum norm procedure, morphing those estimates onto a common cortical template and calculating the patterns of activity

  3. Group Analysis in MNE-Python of Evoked Responses from a Tactile Stimulation Paradigm: A Pipeline for Reproducibility at Every Step of Processing, Going from Individual Sensor Space Representations to an across-Group Source Space Representation

    Directory of Open Access Journals (Sweden)

    Lau M. Andersen

    2018-01-01

    Full Text Available An important aim of an analysis pipeline for magnetoencephalographic data is that it allows for the researcher spending maximal effort on making the statistical comparisons that will answer the questions of the researcher, while in turn spending minimal effort on the intricacies and machinery of the pipeline. I here present a set of functions and scripts that allow for setting up a clear, reproducible structure for separating raw and processed data into folders and files such that minimal effort can be spend on: (1 double-checking that the right input goes into the right functions; (2 making sure that output and intermediate steps can be accessed meaningfully; (3 applying operations efficiently across groups of subjects; (4 re-processing data if changes to any intermediate step are desirable. Applying the scripts requires only general knowledge about the Python language. The data analyses are neural responses to tactile stimulations of the right index finger in a group of 20 healthy participants acquired from an Elekta Neuromag System. Two analyses are presented: going from individual sensor space representations to, respectively, an across-group sensor space representation and an across-group source space representation. The processing steps covered for the first analysis are filtering the raw data, finding events of interest in the data, epoching data, finding and removing independent components related to eye blinks and heart beats, calculating participants' individual evoked responses by averaging over epoched data and calculating a grand average sensor space representation over participants. The second analysis starts from the participants' individual evoked responses and covers: estimating noise covariance, creating a forward model, creating an inverse operator, estimating distributed source activity on the cortical surface using a minimum norm procedure, morphing those estimates onto a common cortical template and calculating the patterns

  4. Purification, crystallization and X-ray characterization of a Kunitz-type trypsin inhibitor protein from the seeds of chickpea (Cicer arietinum).

    Science.gov (United States)

    Sharma, Urvashi; Suresh, C G

    2011-06-01

    A Kunitz-type trypsin inhibitor protein (CPTI) purified from chickpea seeds was estimated to have a molecular mass of 18 kDa on SDS-PAGE. The IC(50) value of CPTI was determined to be 2.5 µg against trypsin. The inhibitory activity of CPTI is 114 TIU (trypsin inhibitory units) per milligram of protein, which is high compared with those of other known Kunitz-type trypsin inhibitors from legumes. CPTI crystallized in three different orthorhombic crystal forms: P2(1)2(1)2 form A, P2(1)2(1)2 form B and P2(1)2(1)2(1). The crystals of P2(1)2(1)2 form A, with unit-cell parameters a = 37.2, b = 41.2, c = 104.6 Å, diffracted to 2.0 Å resolution at the home source and to 1.4 Å on beamline BM14 at the ESRF. Data were also collected from crystals grown in the presence of iodine. The Matthews coefficient for these crystals was calculated to be 2.37 Å(3) Da(-1), corresponding to a solvent content of 42%. The other two crystal forms (P2(1)2(1)2 form B and P2(1)2(1)2(1)) diffracted comparatively poorly.

  5. Real Elements and p-Nilpotence of Finite Groups

    Directory of Open Access Journals (Sweden)

    Adolfo Ballester-Bolinches

    2016-12-01

    Full Text Available Our first main result proves that every element of order 4 of a Sylow 2-subgroup S of a minimal non-2-nilpotent group G, is a real element of S. This allows to give a character-free proof of a theorem due to Isaacs and Navarro (see [9, Theorem B]. As an application, the authors show a common extension of the p-nilpotence criteria proved in [3] and [9].

  6. Representation theory of 2-groups on finite dimensional 2-vector spaces

    OpenAIRE

    Elgueta, Josep

    2004-01-01

    In this paper, the 2-category $\\mathfrak{Rep}_{{\\bf 2Mat}_{\\mathbb{C}}}(\\mathbb{G})$ of (weak) representations of an arbitrary (weak) 2-group $\\mathbb{G}$ on (some version of) Kapranov and Voevodsky's 2-category of (complex) 2-vector spaces is studied. In particular, the set of equivalence classes of representations is computed in terms of the invariants $\\pi_0(\\mathbb{G})$, $\\pi_1(\\mathbb{G})$ and $[\\alpha]\\in H^3(\\pi_0(\\mathbb{G}),\\pi_1(\\mathbb{G}))$ classifying $\\mathbb{G}$. Also the categ...

  7. Acute Ankle Sprain in a Mouse Model: Changes in Knee-Joint Space.

    Science.gov (United States)

    Hubbard-Turner, Tricia; Wikstrom, Erik A; Guderian, Sophie; Turner, Michael J

    2017-06-02

      Ankle sprains remain the most common orthopaedic injury. Conducting long-term studies in humans is difficult and costly, so the long-term consequences of an ankle sprain are not entirely known.   To measure knee-joint space after a single surgically induced ankle sprain in mice.   Randomized controlled trial.   University research laboratory.   Thirty male mice (CBA/2J) were randomly placed into 1 of 3 surgical groups: the transected calcaneofibular ligament (CFL) group, the transected anterior talofibular ligament/CFL group, or a sham treatment group. The right ankle was operated on in all mice.   Three days after surgery, all of the mice were individually housed in cages containing a solid-surface running wheel, and daily running-wheel measurements were recorded. Before surgery and every 6 weeks after surgery, a diagnostic ultrasound was used to measure medial and lateral knee-joint space in both hind limbs.   Right medial (P = .003), right lateral (P = .002), left medial (P = .03), and left lateral (P = .002) knee-joint spaces decreased across the life span. The mice in the anterior talofibular ligament/CFL group had decreased right medial (P = .004) joint space compared with the sham and CFL groups starting at 24 weeks of age and continuing throughout the life span. No differences occurred in contralateral knee-joint degeneration among any of the groups.   Based on current data, mice that sustained a surgically induced severe ankle sprain developed greater joint degeneration in the ipsilateral knee. Knee degeneration could result from accommodation to the laxity of the ankle or biomechanical alterations secondary to ankle instability. A single surgically induced ankle sprain could significantly affect knee-joint function.

  8. Multiloop calculations in p-adic string theory and Bruhat-Tits trees.2

    International Nuclear Information System (INIS)

    Zabrodin, A.V.; Mironov, A.D.; Chekhov, L.O.

    1989-01-01

    The open p-adic string world sheet as a coset space F=T/Γ, where T is the Bruhat-Tits tree for the p-adic linear group GL(2.Q p ) is some Schottky group is treated. The boundary of this world sheet corresponds to p-adic Mumford curve of finite genus. The string dynamics is governed by the local Gaussian action on the coset space F. The tachyon amplitudes expressed in terms of p-adic Θ-functions are proposed for the Mumford curve of arbitrary genus and compared with the corresponding usual archimedian amplitudes. 41 refs.; 14 figs

  9. Independence of automorphism group, center, and state space of quantum logics

    International Nuclear Information System (INIS)

    Navara, M.

    1992-01-01

    We prove that quantum logics (-orthomodular posets) admit full independence of the attributes important within the foundations of quantum mechanics. Namely, we present the construction of quantum logics with given sublogics (=physical subsystems), automorphism groups, centers (=open-quotes classical partsclose quotes of the systems), and state spaces. Thus, all these open-quotes parametersclose quotes are independent. Our result is rooted in the line of investigation carried out by Greechie; Kallus and Trnkova; Kalmbach; and Navara and Ptak; and considerably enriches the known algebraic methods in orthomodular posets. 19 refs., 1 fig

  10. Multiloop calculations in p-adic string theory and Bruhat-Tits trees. 1

    International Nuclear Information System (INIS)

    Zabrodin, A.V.; Mironov, A.D.; Chekhov, L.O.

    1989-01-01

    The open p-adic string world sheet as a coset space F=T/Γ, where T is the Bruhat-Tits three for the p-adic linear group GL(2.Q p ) and Γ is contained it PGL(2.Q p ) is some Schottky group is treated. The boundary of this world sheet corresponds to p-adic Mumford curve of finite genus. The string dynamics is governed by the local gaussian action on the coset space F. The tachyon amplitudes expressed in terms of p-adic Θ-functions are proposed for the Mumford curve of arbitrary genus and compared them with the corresponding usual archimedian amplitudes. 25 refs.; 5 figs

  11. Low dark current p-on-n technology for space applications

    Science.gov (United States)

    Péré-Laperne, N.; Baier, N.; Cervera, C.; Santailler, J. L.; Lobre, C.; Cassillo, C.; Berthoz, J.; Destefanis, V.; Sam Giao, D.; Lamoure, A.

    2017-08-01

    Space applications are requiring low dark current in the long wave infrared at low operating temperature for low flux observation. The applications envisioned with this type of specification are namely scientific and planetary missions. Within the framework of the joint laboratory between Sofradir and the CEA-LETI, a specific development of a TV format focal plane array with a cut-off wavelength of 12.5μm at 40K has been carried out. For this application, the p on n technology has been used. It is based on an In doped HgCdTe absorbing material grown by Liquid Phase Epitaxy (LPE) and an As implanted junction area. This architecture allows decreasing both dark current and series resistance compared to the legacy n on p technology based on Hg vacancies. In this paper, the technological improvements are briefly described. These technological tunings led to a 35% decrease of dark current in the diffusion regime. CEA-LETI and Sofradir demonstrated the ability to use the p on n technology with a long cutoff wavelength in the infrared range.

  12. Does the Health Impact of Exposure to Neighbourhood Green Space Differ between Population Groups? An Explorative Study in Four European Cities

    Science.gov (United States)

    Ruijsbroek, Annemarie; Droomers, Mariël; Kruize, Hanneke; van Kempen, Elise; Gidlow, Christopher J.; Hurst, Gemma; Andrusaityte, Sandra; Nieuwenhuijsen, Mark J.; Maas, Jolanda; Hardyns, Wim; Stronks, Karien; Groenewegen, Peter P.

    2017-01-01

    It has been suggested that certain residents, such as those with a low socioeconomic status, the elderly, and women, may benefit more from the presence of neighbourhood green space than others. We tested this hypothesis for age, gender, educational level, and employment status in four European cities. Data were collected in Barcelona (Spain; n = 1002), Kaunas (Lithuania; n = 989), Doetinchem (The Netherlands; n = 847), and Stoke-on-Trent (UK; n = 933) as part of the EU-funded PHENOTYPE project. Surveys were used to measure mental and general health, individual characteristics, and perceived neighbourhood green space. Additionally, we used audit data about neighbourhood green space. In Barcelona, there were positive associations between neighbourhood green space and general health among low-educated residents. In the other cities and for the other population groups, there was little evidence that the association between health and neighbourhood green space differed between population groups. Overall, our study does not support the assumption that the elderly, women, and residents who are not employed full-time benefit more from neighbourhood green space than others. Only in the highly urbanised city of Barcelona did the low-educated group benefit from neighbourhood green spaces. Perhaps neighbourhood green spaces are more important for the health of low-educated residents in particularly highly urbanised areas. PMID:28594390

  13. Does the Health Impact of Exposure to Neighbourhood Green Space Differ between Population Groups? An Explorative Study in Four European Cities.

    Science.gov (United States)

    Ruijsbroek, Annemarie; Droomers, Mariël; Kruize, Hanneke; van Kempen, Elise; Gidlow, Christopher J; Hurst, Gemma; Andrusaityte, Sandra; Nieuwenhuijsen, Mark J; Maas, Jolanda; Hardyns, Wim; Stronks, Karien; Groenewegen, Peter P

    2017-06-08

    It has been suggested that certain residents, such as those with a low socioeconomic status, the elderly, and women, may benefit more from the presence of neighbourhood green space than others. We tested this hypothesis for age, gender, educational level, and employment status in four European cities. Data were collected in Barcelona (Spain; n = 1002), Kaunas (Lithuania; n = 989), Doetinchem (The Netherlands; n = 847), and Stoke-on-Trent (UK; n = 933) as part of the EU-funded PHENOTYPE project. Surveys were used to measure mental and general health, individual characteristics, and perceived neighbourhood green space. Additionally, we used audit data about neighbourhood green space. In Barcelona, there were positive associations between neighbourhood green space and general health among low-educated residents. In the other cities and for the other population groups, there was little evidence that the association between health and neighbourhood green space differed between population groups. Overall, our study does not support the assumption that the elderly, women, and residents who are not employed full-time benefit more from neighbourhood green space than others. Only in the highly urbanised city of Barcelona did the low-educated group benefit from neighbourhood green spaces. Perhaps neighbourhood green spaces are more important for the health of low-educated residents in particularly highly urbanised areas.

  14. R-102, 1 Group Space-Independent Inverse Reactor Kinetics

    International Nuclear Information System (INIS)

    Kaganove, J.J.

    1966-01-01

    1 - Description of problem or function: Given the space-independent, one energy group reactor kinetics equations and the initial conditions, this program determines the time variation of reactivity required to produce the given input of flux-time data. 2 - Method of solution: Time derivatives of neutron density are obtained by application of (a) five-point quartic, (b) three-point parabolic, (c) five-point least-mean-square cubic, (d) five-point least-mean-square parabolic, or (e) five-point least-mean-square linear formulae to the neutron density or to the natural logarithm of the neutron density. Between each data point the neutron density is assumed to be (a) exponential*(third-order polynomial), (b) exponential, or (c) linear. Changes in reactivity between data points are obtained algebraically from the kinetics equations, neutron density derivatives, and the algebraic representation of neutron density. First and second time derivatives of the reactivity are obtained by use of any of the formulae applicable to the neutron density. 3 - Restrictions on the complexity of the problem: Maxima of - 50 delay groups; 1000 data points; 99 data blocks (A data block is a sequence of input points characterized by a fixed time-interval between points, a smoothing option, and a number of repetitions of the smoothing option)

  15. Space-group approach to two-electron states in unconventional superconductors

    International Nuclear Information System (INIS)

    Yarzhemsky, V. G.

    2008-01-01

    The direct application of the space-group representation theory, makes possible to obtain limitations for the symmetry of SOP on lines and planes of symmetry in one-electron Brillouin zone. In the case of highly symmetric UPt 3 only theoretical nodal structure of IR E 2u is in agreement with all the experimental results. On the other hand, in the case of high-T c superconductors the two electron description of Cooper pairs in D 2h symmetry is not sufficient to describe experimental nodal structure. It was shown that in this case, the nodal structure is the result of underlying interactions between two-electron states and hidden symmetry D-4 h . (author)

  16. Crystal structure, phytochemical study and enzyme inhibition activity of Ajaconine and Delectinine

    Science.gov (United States)

    Ahmad, Shujaat; Ahmad, Hanif; Khan, Hidayat Ullah; Shahzad, Adnan; Khan, Ezzat; Ali Shah, Syed Adnan; Ali, Mumtaz; Wadud, Abdul; Ghufran, Mehreen; Naz, Humera; Ahmad, Manzoor

    2016-11-01

    The Crystal structure, comparative DFT study and phytochemical investigation of atisine type C-20 diterpenoid alkaloid ajaconine (1) and lycoctonine type C-19 diterpenoid alkaloid delectinine (2) is reported here. These compounds were isolated from Delphinium chitralense. Both the natural products 1 and 2 crystallize in orthorhombic crystal system with identical space group of P212121. The geometric parameters of both compounds were calculated with the help of DFT using B3LYP/6-31+G (p) basis set and HOMO-LUMO energies, optimized band gaps, global hardness, ionization potential, electron affinity and global electrophilicity are calculated. The compounds 1 and 2 were screened for acetyl cholinesterase and butyryl cholinesterase inhibition activities in a dose dependent manner followed by molecular docking to explore the possible inhibitory mechanism of ajaconine (1) and delectinine (2). The IC50 values of tested compounds against AChE were observed as 12.61 μM (compound 1) and 5.04 μM (compound 2). The same experiments were performed for inhibition of BChE and IC50 was observed to be 10.18 μM (1) and 9.21 μM (2). Promising inhibition activity was shown by both the compounds against AChE and BChE in comparison with standard drugs available in the market such as allanzanthane and galanthamine. The inhibition efficiency of both the natural products was determined in a dose dependent manner.

  17. Holomorphic representation of constant mean curvature surfaces in Minkowski space: Consequences of non-compactness in loop group methods

    DEFF Research Database (Denmark)

    Brander, David; Rossman, Wayne; Schmitt, Nicholas

    2010-01-01

    We give an infinite dimensional generalized Weierstrass representation for spacelike constant mean curvature (CMC) surfaces in Minkowski 3-space $\\R^{2,1}$. The formulation is analogous to that given by Dorfmeister, Pedit and Wu for CMC surfaces in Euclidean space, replacing the group $SU_2$ with...

  18. Isometries on Banach spaces function spaces

    CERN Document Server

    Fleming, Richard J

    2002-01-01

    Fundamental to the study of any mathematical structure is an understanding of its symmetries. In the class of Banach spaces, this leads naturally to a study of isometries-the linear transformations that preserve distances. In his foundational treatise, Banach showed that every linear isometry on the space of continuous functions on a compact metric space must transform a continuous function x into a continuous function y satisfying y(t) = h(t)x(p(t)), where p is a homeomorphism and |h| is identically one.Isometries on Banach Spaces: Function Spaces is the first of two planned volumes that survey investigations of Banach-space isometries. This volume emphasizes the characterization of isometries and focuses on establishing the type of explicit, canonical form given above in a variety of settings. After an introductory discussion of isometries in general, four chapters are devoted to describing the isometries on classical function spaces. The final chapter explores isometries on Banach algebras.This treatment p...

  19. Direct gauging of the Poincare group V. Group scaling, classical gauge theory, and gravitational corrections

    International Nuclear Information System (INIS)

    Edelen, D.G.B.

    1986-01-01

    Homogeneous scaling of the group space of the Poincare group, P 10 , is shown to induce scalings of all geometric quantities associated with the local action of P 10 . The field equations for both the translation and the Lorentz rotation compensating fields reduce to O(1) equations if the scaling parameter is set equal to the general relativistic gravitational coupling constant 8πGc -4 . Standard expansions of all field variables in power series in the scaling parameter give the following results. The zeroth-order field equations are exactly the classical field equations for matter fields on Minkowski space subject to local action of an internal symmetry group (classical gauge theory). The expansion process is shown to break P 10 -gauge covariance of the theory, and hence solving the zeroth-order field equations imposes an implicit system of P 10 -gauge conditions. Explicit systems of field equations are obtained for the first- and higher-order approximations. The first-order translation field equations are driven by the momentum-energy tensor of the matter and internal compensating fields in the zeroth order (classical gauge theory), while the first-order Lorentz rotation field equations are driven by the spin currents of the same classical gauge theory. Field equations for the first-order gravitational corrections to the matter fields and the gauge fields for the internal symmetry group are obtained. Direct Poincare gauge theory is thus shown to satisfy the first two of the three-part acid test of any unified field theory. Satisfaction of the third part of the test, at least for finite neighborhoods, seems probable

  20. On reflexivity of random walks in a random environment on a metric space

    International Nuclear Information System (INIS)

    Rozikov, U.A.

    2002-11-01

    In this paper, we consider random walks in random environments on a countable metric space when jumps of the walks of the fractions are finite. The transfer probabilities of the random walk from x is an element of G (where G is the considering metric space) are defined by vector p(x) is an element of R k , k>1, where {p(x), x is an element of G} is the set of independent and indentically distributed random vectors. For the random walk, a sufficient condition of nonreflexivity is obtained. Examples for metric spaces Z d free groups and free product of finite numbers cyclic groups of the second order and some other metric spaces are considered. (author)

  1. Response to the Comment by G. Emch on projective group representations in quaternionic Hilbert space

    International Nuclear Information System (INIS)

    Adler, S.L.

    1996-01-01

    We discuss the differing definitions of complex and quaternionic projective group representations employed by us and by Emch. The definition of Emch (termed here a strong projective representation) is too restrictive to accommodate quaternionic Hilbert space embeddings of complex projective representations. Our definition (termed here a weak projective representation) encompasses such embeddings, and leads to a detailed theory of quaternionic, as well as complex, projective group representations. copyright 1996 American Institute of Physics

  2. Polymorphism in 2-X-adamantane derivatives (X = Cl, Br).

    Science.gov (United States)

    Negrier, Philippe; Barrio, María; Tamarit, Josep Ll; Mondieig, Denise

    2014-08-14

    The polymorphism of two 2-X-adamantane derivatives, X = Cl, X = Br, has been studied by X-ray powder diffraction and normal- and high-pressure (up to 300 MPa) differential scanning calorimetry. 2-Br-adamantane displays a low-temperature orthorhombic phase (space group P212121, Z = 4) and a high-temperature plastic phase (Fm3̅m, Z = 4) from 277.9 ± 1.0 K to the melting point at 413.4 ± 1.0 K. 2-Cl-adamantane presents a richer polymorphic behavior through the temperature range studied. At low temperature it displays a triclinic phase (P1̅, Z = 2), which transforms to a monoclinic phase (C2/c, Z = 8) at 224.4 ± 1.0 K, both phases being ordered. Two high-temperature orientationally disordered are found for this compound, one hexagonal (P63/mcm, Z = 6) at ca. 241 K and the highest one, cubic (Fm3̅m, Z = 4), being stable from 244 ± 1.0 K up to the melting point at 467.5 ± 1.0 K. No additional phase appears due to the increase in pressure within the studied range. The intermolecular interactions are found to be weak, especially for the 2-Br-adamantane compound for which the Br···Br as well as C-Br···H distances are larger than the addition of the van der Waals radii, thus confirming the availability of this compound for building up diamondoid blocks.

  3. Raman scattering tensors of tyrosine.

    Science.gov (United States)

    Tsuboi, M; Ezaki, Y; Aida, M; Suzuki, M; Yimit, A; Ushizawa, K; Ueda, T

    1998-01-01

    Polarized Raman scattering measurements have been made of a single crystal of L-tyrosine by the use of a Raman microscope with the 488.0-nm exciting beam from an argon ion laser. The L-tyrosine crystal belongs to the space group P2(1)2(1)2(1) (orthorhombic), and Raman scattering intensities corresponding to the aa, bb, cc, ab and ac components of the crystal Raman tensor have been determined for each prominent Raman band. A similar set of measurements has been made of L-tyrosine-d4, in which four hydrogen atoms on the benzene ring are replaced by deuterium atoms. The effects of NH3-->ND3 and OH-->OD on the Raman spectrum have also been examined. In addition, depolarization ratios of some bands of L-tyrosine in aqueous solutions of pH 13 and pH 1 were examined. For comparison with these experimental results, on the other hand, ab initio molecular orbital calculations have been made of the normal modes of vibration and their associated polarizability oscillations of the L-tyrosine molecule. On the basis of these experimental data and by referring to the results of the calculations, discussions have been presented on the Raman tensors associated to some Raman bands, including those at 829 cm-1 (benzene ring breathing), 642 cm-1 (benzene ring deformation), and 432 cm-1 (C alpha-C beta-C gamma bending).

  4. Structure of some relative relation modules of finite p-groups

    International Nuclear Information System (INIS)

    Yamin, M.

    1990-06-01

    Let G be a finite p-group generated by (g i , 1 ≤ i ≤ d), G i the cyclic subgroup generated by g i , E the free product of the G i , 1 ≤ i ≤ d, and S the kernel of the natural epimorphism of E onto G. The largest elementary abelian p-quotient S-circumflex = S/S'S p , regarded as an IF p G-module via conjugation in E, is called a relative relation module of G. If d is the minimum number of generaters for G, the author has proved that S-circumflex is nonprojective and indecomposable. The aim of this paper is to give an alternative proof for the indecomposability of S-circumflex; the proof here is more informative as it deals with Loewy structure and generating sets of S-circumflex and other associated modules. (author). 9 refs

  5. Does the Health Impact of Exposure to Neighbourhood Green Space Differ between Population Groups? An Explorative Study in Four European Cities

    Directory of Open Access Journals (Sweden)

    Annemarie Ruijsbroek

    2017-06-01

    Full Text Available It has been suggested that certain residents, such as those with a low socioeconomic status, the elderly, and women, may benefit more from the presence of neighbourhood green space than others. We tested this hypothesis for age, gender, educational level, and employment status in four European cities. Data were collected in Barcelona (Spain; n = 1002, Kaunas (Lithuania; n = 989, Doetinchem (The Netherlands; n = 847, and Stoke-on-Trent (UK; n = 933 as part of the EU-funded PHENOTYPE project. Surveys were used to measure mental and general health, individual characteristics, and perceived neighbourhood green space. Additionally, we used audit data about neighbourhood green space. In Barcelona, there were positive associations between neighbourhood green space and general health among low-educated residents. In the other cities and for the other population groups, there was little evidence that the association between health and neighbourhood green space differed between population groups. Overall, our study does not support the assumption that the elderly, women, and residents who are not employed full-time benefit more from neighbourhood green space than others. Only in the highly urbanised city of Barcelona did the low-educated group benefit from neighbourhood green spaces. Perhaps neighbourhood green spaces are more important for the health of low-educated residents in particularly highly urbanised areas.

  6. Gauge fields in nonlinear group realizations involving two-dimensional space-time symmetry

    International Nuclear Information System (INIS)

    Machacek, M.E.; McCliment, E.R.

    1975-01-01

    It is shown that gauge fields may be consistently introduced into a model Lagrangian previously considered by the authors. The model is suggested by the spontaneous breaking of a Lorentz-type group into a quasiphysical two-dimensional space-time and one internal degree of freedom, loosely associated with charge. The introduction of zero-mass gauge fields makes possible the absorption via the Higgs mechanism of the Goldstone fields that appear in the model despite the fact that the Goldstone fields do not transform as scalars. Specifically, gauge invariance of the Yang-Mills type requires the introduction of two sets of massless gauge fields. The transformation properties in two-dimensional space-time suggest that one set is analogous to a charge doublet that behaves like a second-rank tensor in real four-dimensional space time. The other set suggests a spin-one-like charge triplet. Via the Higgs mechanism, the first set absorbs the Goldstone fields and acquires mass. The second set remains massless. If massive gauge fields are introduced, the associated currents are not conserved and the Higgs mechanism is no longer fully operative. The Goldstone fields are not eliminated, but coupling between the Goldstone fields and the gauge fields does shift the mass of the antisymmetric second-rank-tensor gauge field components

  7. In silico approaches and chemical space of anti-P-type ATPase compounds for discovering new antituberculous drugs.

    Science.gov (United States)

    Santos, Paola; López-Vallejo, Fabian; Soto, Carlos-Y

    2017-08-01

    Tuberculosis (TB) is one of the most important public health problems around the world. The emergence of multi-drug-resistant (MDR) and extensively drug-resistant (XDR) Mycobacterium tuberculosis strains has driven the finding of alternative anti-TB targets. In this context, P-type ATPases are interesting therapeutic targets due to their key role in ion homeostasis across the plasma membrane and the mycobacterial survival inside macrophages. In this review, in silico and experimental strategies used for the rational design of new anti-TB drugs are presented; in addition, the chemical space distribution based on the structure and molecular properties of compounds with anti-TB and anti-P-type ATPase activity is discussed. The chemical space distribution compared to public compound libraries demonstrates that natural product libraries are a source of novel chemical scaffolds with potential anti-P-type ATPase activity. Furthermore, compounds that experimentally display anti-P-type ATPase activity belong to a chemical space of molecular properties comparable to that occupied by those approved for oral use, suggesting that these kinds of molecules have a good pharmacokinetic profile (drug-like) for evaluation as potential anti-TB drugs. © 2017 John Wiley & Sons A/S.

  8. Banded versus Single-sided bonded space maintainers: A Comparative Study

    Directory of Open Access Journals (Sweden)

    Sudhir Mittal

    2018-01-01

    Full Text Available Background: The present study is conducted to evaluate and compare the clinical performance of conventional band and loop space maintainer and fiber reinforced composite resin (FRCR space maintainers. Materials and Methods: A total of 45 extraction sites in the age group of 6–9 years having premature loss of primary molars or indicated for extraction were selected for the study. The patients were randomly divided into three groups as Group I, in which conventional band and loop space maintainer was given, Group II and Group III (FRCR, in which FRCR (everStick CandB and impregnated glass fibers (Interlig space maintainers were given, respectively. Patients were recalled at 3, 6, and 12-month interval for evaluation of all the three types of space maintainer. Results: Overall success rate of Group I was 86.7%, for Group II was 80%, and for Group III was 73.3% at the end of the study. Patient acceptability was significantly higher in Group II and Group III (FRCR as compared to Group I (Conventional band and loop. In Group I, cement loss and fracture of loop, whereas in Group II and Group III, debonding at enamel composite was the most common failure followed by debonding at fiber composite and fiber fracture. FRCR space maintainers were found to be cost-effective as compared to Group I. More linear changes and angular changes were recorded in Group I as compared to Group II and Group III but difference was not significant (P > 0.05. Conclusion: Only single (buccal surface application of FRCR space maintainers showed almost equal clinical efficacy compared to conventional band and loop space maintainer with significantly better patient acceptability, less cost, and time taken.

  9. A summary of activities of the US/Soviet-Russian joint working group on space biology and medicine

    Science.gov (United States)

    Doarn, Charles R.; Nicogossian, Arnauld E.; Grigoriev, Anatoly I.; Tverskaya, Galina; Orlov, Oleg I.; Ilyin, Eugene A.; Souza, Kenneth A.

    2010-10-01

    The very foundation of cooperation between the United States (US) and Russia (former Soviet Union) in space exploration is a direct result of the mutual desire for scientific understanding and the creation of a collaborative mechanism—the Joint Working Group (JWG) on Space Biology and Medicine. From the dawn of the space age, it has been the quest of humankind to understand its place in the universe. While nations can and do solve problems independently, it takes nations, working together, to accomplish great things. The formation of the JWG provided an opportunity for the opening of a series of productive relationships between the superpowers, the US and the Union of Soviet Socialist Republics (USSR); and served as a justification for continued relationship for medical assistance in spaceflight, and to showcase Earth benefits from space medicine research. This relationship has been played out on an international scale with the construction and operation of the International Space Station. The fundamental reason for this successful endeavor is a direct result of the spirit and perseverance of the men and women who have worked diligently side-by-side to promote science and move our understanding of space forward. This manuscript provides a historical perspective of the JWG; how it came about; its evolution; what it accomplished; and what impact it has had and continues to have in the 21st century with regard to human spaceflight and space life sciences research. It captures the spirit of this group, which has been in continuous existence for over 40 years, and provides a never before reported summary of its activities.

  10. Topological and homological properties of the orbit space of a compact linear Lie group with commutative connected component

    OpenAIRE

    Styrt, O. G.

    2016-01-01

    The problem in question is whether the quotient space of a compact linear group is a topological manifold and whether it is a homological manifold. In the paper, the case of an infinite group with commutative connected component is considered.

  11. Proximal tubular hypertrophy and enlarged glomerular and proximal tubular urinary space in obese subjects with proteinuria.

    Directory of Open Access Journals (Sweden)

    Ana Tobar

    Full Text Available BACKGROUND: Obesity is associated with glomerular hyperfiltration, increased proximal tubular sodium reabsorption, glomerular enlargement and renal hypertrophy. A single experimental study reported an increased glomerular urinary space in obese dogs. Whether proximal tubular volume is increased in obese subjects and whether their glomerular and tubular urinary spaces are enlarged is unknown. OBJECTIVE: To determine whether proximal tubules and glomerular and tubular urinary space are enlarged in obese subjects with proteinuria and glomerular hyperfiltration. METHODS: Kidney biopsies from 11 non-diabetic obese with proteinuria and 14 non-diabetic lean patients with a creatinine clearance above 50 ml/min and with mild or no interstitial fibrosis were retrospectively analyzed using morphometric methods. The cross-sectional area of the proximal tubular epithelium and lumen, the volume of the glomerular tuft and of Bowman's space and the nuclei number per tubular profile were estimated. RESULTS: Creatinine clearance was higher in the obese than in the lean group (P=0.03. Proteinuria was similarly increased in both groups. Compared to the lean group, the obese group displayed a 104% higher glomerular tuft volume (P=0.001, a 94% higher Bowman's space volume (P=0.003, a 33% higher cross-sectional area of the proximal tubular epithelium (P=0.02 and a 54% higher cross-sectional area of the proximal tubular lumen (P=0.01. The nuclei number per proximal tubular profile was similar in both groups, suggesting that the increase in tubular volume is due to hypertrophy and not to hyperplasia. CONCLUSIONS: Obesity-related glomerular hyperfiltration is associated with proximal tubular epithelial hypertrophy and increased glomerular and tubular urinary space volume in subjects with proteinuria. The expanded glomerular and urinary space is probably a direct consequence of glomerular hyperfiltration. These effects may be involved in the pathogenesis of obesity

  12. Torelli groups, extended Johnson homomorphisms, and new cycles on the moduli space of curves

    DEFF Research Database (Denmark)

    Morita, Shigeyuki; Penner, Robert

    modulo N are derived for all N. Furthermore, the first Johnson homomorphism, which is defined from the classical Torelli group to the third exterior power of the homology of the surface, is shown to lift to an explicit canonical 1-cocycle of the Teichmueller space. The main tool for these results...... cocycle lifts of the higher Johnson homomorphisms....

  13. Analysis of Adult Female Mouse (Mus musculus) Group Behavior on the International Space Station (ISS)

    Science.gov (United States)

    Solomides, P.; Moyer, E. L.; Talyansky, Y.; Choi, S.; Gong, C.; Globus, R. K.; Ronca, A. E.

    2016-01-01

    As interest in long duration effects of space habitation increases, understanding the behavior of model organisms living within the habitats engineered to fly them is vital for designing, validating, and interpreting future spaceflight studies. A handful of papers have previously reported behavior of mice and rats in the weightless environment of space. The Rodent Research Hardware and Operations Validation (Rodent Research-1; RR1) utilized the Rodent Habitat (RH) developed at NASA Ames Research Center to fly mice on the ISS (International Space Station). Ten adult (16-week-old) female C57BL/6 mice were launched on September 21st, 2014 in an unmanned Dragon Capsule, and spent 37 days in microgravity. Here we report group behavioral phenotypes of the RR1 Flight (FLT) and environment-matched Ground Control (GC) mice in the Rodent Habitat (RH) during this long-duration flight. Video was recorded for 33 days on the ISS, permitting daily assessments of overall health and well-being of the mice, and providing a valuable repository for detailed behavioral analysis. We previously reported that, as compared to GC mice, RR1 FLT mice exhibited the same range of behaviors, including eating, drinking, exploration, self- and allo-grooming, and social interactions at similar or greater levels of occurrence. Overall activity was greater in FLT as compared to GC mice, with spontaneous ambulatory behavior, including organized 'circling' or 'race-tracking' behavior that emerged within the first few days of flight following a common developmental sequence, and comprised the primary dark cycle activity persisting throughout the remainder of the experiment. Participation by individual mice increased dramatically over the course of the flight. Here we present a detailed analysis of 'race-tracking' behavior in which we quantified: (1) Complete lap rotations by individual mice; (2) Numbers of collisions between circling mice; (3) Lap directionality; and (4) Recruitment of mice into a group

  14. On the Lie symmetry group for classical fields in noncommutative space

    Energy Technology Data Exchange (ETDEWEB)

    Pereira, Ricardo Martinho Lima Santiago [Universidade Federal da Bahia (UFBA), BA (Brazil); Instituto Federal da Bahia (IFBA), BA (Brazil); Ressureicao, Caio G. da [Universidade Federal da Bahia (UFBA), BA (Brazil). Inst. de Fisica; Vianna, Jose David M. [Universidade Federal da Bahia (UFBA), BA (Brazil); Universidade de Brasilia (UnB), DF (Brazil)

    2011-07-01

    Full text: An alternative way to include effects of noncommutative geometries in field theory is based on the concept of noncommutativity among degrees of freedom of the studied system. In this context it is reasonable to consider that, in the multiparticle noncommutative quantum mechanics (NCQM), the noncommutativity among degrees of freedom to discrete system with N particles is also verified. Further, an analysis of the classical limit of the single particle NCQM leads to a deformed Newtonian mechanics where the Newton's second law is modified in order to include the noncommutative parameter {theta}{sub {iota}j} and, for a one-dimensional discrete system with N particles, the dynamical evolution of each particle is given by this modified Newton's second law. Hence, applying the continuous limit to this multiparticle classical system it is possible to obtain a noncommutative extension of two -dimensional field theory in a noncommutative space. In the present communication we consider a noncommutative extension of the scalar field obtained from this approach and we analyze the Lie symmetries in order to compare the Lie group of this field with the usual scalar field in the commutative space. (author)

  15. Computing Galois Groups of Eisenstein Polynomials Over P-adic Fields

    Science.gov (United States)

    Milstead, Jonathan

    The most efficient algorithms for computing Galois groups of polynomials over global fields are based on Stauduhar's relative resolvent method. These methods are not directly generalizable to the local field case, since they require a field that contains the global field in which all roots of the polynomial can be approximated. We present splitting field-independent methods for computing the Galois group of an Eisenstein polynomial over a p-adic field. Our approach is to combine information from different disciplines. We primarily, make use of the ramification polygon of the polynomial, which is the Newton polygon of a related polynomial. This allows us to quickly calculate several invariants that serve to reduce the number of possible Galois groups. Algorithms by Greve and Pauli very efficiently return the Galois group of polynomials where the ramification polygon consists of one segment as well as information about the subfields of the stem field. Second, we look at the factorization of linear absolute resolvents to further narrow the pool of possible groups.

  16. Hypermultiplet gaugings and supersymmetric solutions from 11D and massive IIA supergravity on H^{(p,q)} spaces

    Science.gov (United States)

    Guarino, Adolfo

    2018-03-01

    Supersymmetric {AdS}4, {AdS}2 × Σ 2 and asymptotically AdS4 black hole solutions are studied in the context of non-minimal N=2 supergravity models involving three vector multiplets (STU-model) and Abelian gaugings of the universal hypermultiplet moduli space. Such models correspond to consistent subsectors of the {SO}(p,q) and {ISO}(p,q) gauged maximal supergravities that arise from the reduction of 11D and massive IIA supergravity on {H}^{(p,q)} spaces down to four dimensions. A unified description of all the models is provided in terms of a square-root prepotential and the gauging of a duality-hidden symmetry pair of the universal hypermultiplet. Some aspects of M-theory and massive IIA holography are mentioned in passing.

  17. Synthesis and Characterization of Rh—Co Butterfly Clusters Capped by Functionally Substituted 1—Alkynes

    Institute of Scientific and Technical Information of China (English)

    ZHUBao-Hua; SUNJie; 等

    2003-01-01

    By the reactions of [Rh2Co2(CO2)12]1 with functionaly substituted alkyne ligands HC≡CR 2(R=FeCp2) and 3(R=2-OH-C6H4COOCH2),respectively in n-hexane at room temperature,two new cluster derivatives [Rh2Co2(CO)6(μ-CO)4(μ4,η2-HC≡CR)] 4(R=FeCp2) and 5 (R=2-OH-C6H4COOCH2) were obtained respectively,The alkyne was inserted into the Co-Co bond of cluster 1 to give two butterfly clusters.Cluster 4 has been determined by single-crystal X-ray diffraction,Crystallographic data:C22H10Co2FeO18Rh2,Mr=813.83,orthorhombic ,space group P212121,a=11.53187(7),b=12.6572(7),c=17.018(1)°↑A,V=2483.9(3)°↑A3,Z=4,Dc=2.176 g/cm3,F(000)=1568,μ=3.233mm-1,the final R=0.0366 and wR=0.0899 for 5367 observed reflections with I>2σ(I).The two clusters have also been characterized by elemental analysis ,IR and 1H-NMR spectroscopy.

  18. Crystallization and preliminary X-ray analysis of a novel Kunitz-type kallikrein inhibitor from Bauhinia bauhinioides

    Science.gov (United States)

    Navarro, Marcos Vicente de A. S.; Vierira, Débora F.; Nagem, Ronaldo A. P.; de Araújo, Ana Paula U.; Oliva, Maria Luiza V.; Garratt, Richard C.

    2005-01-01

    A Kunitz-type protease inhibitor (BbKI) found in Bauhinia bauhinioides seeds has been overexpressed in Escherichia coli and crystallized at 293 K using PEG 4000 as the precipitant. X-ray diffraction data have been collected to 1.87 Å resolution using an in-house X-ray generator. The crystals of the recombinant protein (rBbKI) belong to the orthorhombic space group P212121, with unit-cell parameters a = 46.70, b = 64.14, c = 59.24 Å. Calculation of the Matthews coefficient suggests the presence of one monomer of rBbKI in the asymmetric unit, with a corresponding solvent content of 51% (V M = 2.5 Å3 Da−1). Iodinated crystals were prepared and a derivative data set was also collected at 2.1 Å resolution. Crystals soaked for a few seconds in a cryogenic solution containing 0.5 M NaI were found to be reasonably isomorphous to the native crystals. Furthermore, the presence of iodide anions could be confirmed in the NaI-derivatized crystal. Data sets from native and derivative crystals are being evaluated for use in crystal structure determination by means of the SIRAS (single isomorphous replacement with anomalous scattering) method. PMID:16511193

  19. Experimental and density functional theory (DFT): A dual approach to probe the key properties of creatininium L-tartrate monohydrate single crystal for nonlinear optical applications

    Science.gov (United States)

    Thirumurugan, R.; Babu, B.; Anitha, K.; Chandrasekaran, J.

    2017-12-01

    A novel organic nonlinear optical (NLO) material, creatininium L-tartrate monohydrate (CTM) was synthesized and it was grown as single crystals with optical quality. 1H and 13C NMR spectral studies were performed and molecular structure of synthesized CTM compound was confirmed. Single crystal X-ray diffraction (SXRD) analysis confirmed that CTM was crystallized in orthorhombic system with non-centrosymmetric (NCS), P212121, space group. The grown crystal exhibited admirable properties such as second harmonic generation efficiency (SHG) (1.9 times KDP), and high laser damage threshold (LDT) value of 3.7 GW cm-2. CTM crystal displayed high transparency (∼60%) in the visible and near-IR region with low cut-off wavelength at 249 nm. Photoluminescence study confirmed blue wavelength emission (∼463 nm) of grown crystal. Thermal and mechanical behaviours have been successfully analysed for grown crystals. The dielectric studies were carried out for grown crystal as a function of frequencies at different temperatures. Hirshfeld surface and fingerprint plots provided the percentage of individual interactions contributed by each atom. Moreover, density functional theory (DFT) calculations have been employed to probe the frontier molecular orbitals (FMOs) and first hyperpolarizability (β) analysis of the optimized CTM structure. These results validated CTM as a suitable NLO candidate and were discussed in this work.

  20. Synthesis, Structural Characterization, and Antitumor Activity of a Ca(II Coordination Polymer Based on 1,6-Naphthalenedisulfonate and 4,4′-Bipyridyl

    Directory of Open Access Journals (Sweden)

    Xishi Tai

    2013-08-01

    Full Text Available A novel Ca(II coordination polymer, [CaL(4,4′-bipyridyl(H2O4]n (L = 1,6-naphthalenedisulfonate, was synthesized by reaction of calcium perchlorate with 1,6-naphthalenedisulfonic acid disodium salt and 4,4′-bipyridyl in CH3CH2OH/H2O. It was characterized by elemental analysis, IR, molar conductivity and thermogravimetric analysis. X-ray crystallography reveals that the Ca(II coordination polymer belongs to the orthorhombic system, with space group P212121. The geometry of the Ca(II ion is a distorted CaNO6 pengonal bipyramid, arising from its coordination by four water molecules, one nitrogen atom of 4,4′-bipyridyl molecule, and two oxygen atoms from two L ligands. The complex molecules form a helical chain by self-assembly. The antitumor activity of 1,6-naphthalenedisulfonic acid disodium salt and the Ca(II coordination polymer against human hepatoma smmc-7721 cell line and human lung adenocarcinoma A549 cell line reveals that the Ca(II coordination polymer inhibits cell growth of human lung adenocarcinoma A549 cell line with IC50 value of 27 μg/mL, and is more resistive to human lung adenocarcinoma A549 cell line as compared to 1,6-naphthalenedisulfonic acid disodium salt.

  1. Implementation of rigorous renormalization group method for ground space and low-energy states of local Hamiltonians

    Science.gov (United States)

    Roberts, Brenden; Vidick, Thomas; Motrunich, Olexei I.

    2017-12-01

    The success of polynomial-time tensor network methods for computing ground states of certain quantum local Hamiltonians has recently been given a sound theoretical basis by Arad et al. [Math. Phys. 356, 65 (2017), 10.1007/s00220-017-2973-z]. The convergence proof, however, relies on "rigorous renormalization group" (RRG) techniques which differ fundamentally from existing algorithms. We introduce a practical adaptation of the RRG procedure which, while no longer theoretically guaranteed to converge, finds matrix product state ansatz approximations to the ground spaces and low-lying excited spectra of local Hamiltonians in realistic situations. In contrast to other schemes, RRG does not utilize variational methods on tensor networks. Rather, it operates on subsets of the system Hilbert space by constructing approximations to the global ground space in a treelike manner. We evaluate the algorithm numerically, finding similar performance to density matrix renormalization group (DMRG) in the case of a gapped nondegenerate Hamiltonian. Even in challenging situations of criticality, large ground-state degeneracy, or long-range entanglement, RRG remains able to identify candidate states having large overlap with ground and low-energy eigenstates, outperforming DMRG in some cases.

  2. Renormalization group approach to a p-wave superconducting model

    International Nuclear Information System (INIS)

    Continentino, Mucio A.; Deus, Fernanda; Caldas, Heron

    2014-01-01

    We present in this work an exact renormalization group (RG) treatment of a one-dimensional p-wave superconductor. The model proposed by Kitaev consists of a chain of spinless fermions with a p-wave gap. It is a paradigmatic model of great actual interest since it presents a weak pairing superconducting phase that has Majorana fermions at the ends of the chain. Those are predicted to be useful for quantum computation. The RG allows to obtain the phase diagram of the model and to study the quantum phase transition from the weak to the strong pairing phase. It yields the attractors of these phases and the critical exponents of the weak to strong pairing transition. We show that the weak pairing phase of the model is governed by a chaotic attractor being non-trivial from both its topological and RG properties. In the strong pairing phase the RG flow is towards a conventional strong coupling fixed point. Finally, we propose an alternative way for obtaining p-wave superconductivity in a one-dimensional system without spin–orbit interaction.

  3. A Topic Space Oriented User Group Discovering Scheme in Social Network: A Trust Chain Based Interest Measuring Perspective

    Directory of Open Access Journals (Sweden)

    Wang Dong

    2016-01-01

    Full Text Available Currently, user group has become an effective platform for information sharing and communicating among users in social network sites. In present work, we propose a single topic user group discovering scheme, which includes three phases: topic impact evaluation, interest degree measurement, and trust chain based discovering, to enable selecting influential topic and discovering users into a topic oriented group. Our main works include (1 an overview of proposed scheme and its related definitions; (2 topic space construction method based on topic relatedness clustering and its impact (influence degree and popularity degree evaluation; (3 a trust chain model to take user relation network topological information into account with a strength classification perspective; (4 an interest degree (user explicit and implicit interest degree evaluation method based on trust chain among users; and (5 a topic space oriented user group discovering method to group core users according to their explicit interest degrees and to predict ordinary users under implicit interest and user trust chain. Finally, experimental results are given to explain effectiveness and feasibility of our scheme.

  4. Moduli space of self-dual connections in dimension greater than four for abelian Gauge groups

    OpenAIRE

    Cappelle, Natacha

    2018-01-01

    In 1954, C. Yang and R. Mills created a Gauge Theory for strong interaction of Elementary Particles. More generally, they proved that it is possible to define a Gauge Theory with an arbitrary compact Lie group as Gauge group. Within this context, it is interesting to find critical values of a functional defined on the space of connections: the Yang-Mills functional. If the based manifold is four dimensional, there exists a natural notion of (anti-)self-dual 2-form, which gives a natural notio...

  5. Cubic scattering amplitudes for all massless representations of the Poincare group in any space-time dimension

    International Nuclear Information System (INIS)

    Fradkin, E.S.; Metsaev, R.R.

    1996-02-01

    Using the language of highest weight representations and the light cone formalism we construct a full list of cubic amplitudes of scattering for all bosonic massless representations of the Poincare group in any even space-time dimension. (author). 29 refs

  6. Clifford algebras, spinors, spin groups and covering groups

    International Nuclear Information System (INIS)

    Magneville, C.; Pansart, J.P.

    1991-03-01

    The Dirac equation uses matrices named Υ matrices which are representations of general algebraic structures associated with a metric space. These algebras are the Clifford algebras. In the first past, these algebras are studied. Then the notion of spinor is developed. It is shown that Majorana and Weyl spinors only exist for some particular metric space. In the second part, Clifford and spinor groups are studied. They may be interpreted as the extension of the notion of orthogonal group for Clifford algebras and their spaces for representation. The rotation of a spinor is computed. In the last part, the connexion between the spinor groups and the Universal Covering Groups is presented [fr

  7. The Hilbert Series of the One Instanton Moduli Space

    CERN Document Server

    Benvenuti, Sergio; Mekareeya, Noppadol; 10.1007

    2010-01-01

    The moduli space of k G-instantons on R^4 for a classical gauge group G is known to be given by the Higgs branch of a supersymmetric gauge theory that lives on Dp branes probing D(p + 4) branes in Type II theories. For p = 3, these (3 + 1) dimensional gauge theories have N = 2 supersymmetry and can be represented by quiver diagrams. The F and D term equations coincide with the ADHM construction. The Hilbert series of the moduli spaces of one instanton for classical gauge groups is easy to compute and turns out to take a particularly simple form which is previously unknown. This allows for a G invariant character expansion and hence easily generalisable for exceptional gauge groups, where an ADHM construction is not known. The conjectures for exceptional groups are further checked using some new techniques like sewing relations in Hilbert Series. This is applied to Argyres-Seiberg dualities.

  8. The Group Evacuation Behavior Based on Fire Effect in the Complicated Three-Dimensional Space

    Directory of Open Access Journals (Sweden)

    Jun Hu

    2014-01-01

    Full Text Available In order to effectively depict the group evacuation behavior in the complicated three-dimensional space, a novel pedestrian flow model is proposed with three-dimensional cellular automata. In this model the calculation methods of floor field and fire gain are elaborated at first, and the transition gain of target position at the next moment is defined. Then, in consideration of pedestrian intimacy and velocity change, the group evacuation strategy and evolution rules are given. Finally, the experiments were conducted with the simulation platform to study the relationships of evacuation time, pedestrian density, average system velocity, and smoke spreading velocity. The results had shown that large-scale group evacuation should be avoided, and in case of large pedestrian density, the shortest route of evacuation strategy would extend system evacuation time.

  9. Quantum spaces, central extensions of Lie groups and related quantum field theories

    Science.gov (United States)

    Poulain, Timothé; Wallet, Jean-Christophe

    2018-02-01

    Quantum spaces with su(2) noncommutativity can be modelled by using a family of SO(3)-equivariant differential *-representations. The quantization maps are determined from the combination of the Wigner theorem for SU(2) with the polar decomposition of the quantized plane waves. A tracial star-product, equivalent to the Kontsevich product for the Poisson manifold dual to su(2) is obtained from a subfamily of differential *-representations. Noncommutative (scalar) field theories free from UV/IR mixing and whose commutative limit coincides with the usual ϕ 4 theory on ℛ3 are presented. A generalization of the construction to semi-simple possibly non simply connected Lie groups based on their central extensions by suitable abelian Lie groups is discussed. Based on a talk presented by Poulain T at the XXVth International Conference on Integrable Systems and Quantum symmetries (ISQS-25), Prague, June 6-10 2017.

  10. Extreme covariant quantum observables in the case of an Abelian symmetry group and a transitive value space

    International Nuclear Information System (INIS)

    Haapasalo, Erkka Theodor; Pellonpaeae, Juha-Pekka

    2011-01-01

    We represent quantum observables as normalized positive operator valued measures and consider convex sets of observables which are covariant with respect to a unitary representation of a locally compact Abelian symmetry group G. The value space of such observables is a transitive G-space. We characterize the extreme points of covariant observables and also determine the covariant extreme points of the larger set of all quantum observables. The results are applied to position, position difference, and time observables.

  11. Size of the lower third molar space in relation to age in Serbian population.

    Science.gov (United States)

    Zelić, Ksenija; Nedeljković, Nenad

    2013-10-01

    It is considered that the shortage of space is the major cause of the third molar impaction. The aim of this study was to establish the frequency of insufficient lower third molar eruption space in Serbian population, to question the differences in this frequency in the subjects of different age, to determine the influence of the lower third molar space (retromolar space) size on third molar eruption, and to investigate a possible correlation between the size of gonial angle and the space/third molar width ratio. Digital orthopantomograms were taken from 93 patients divided into two groups: early adult (16-18 years of age) and adult (18-26) patients. Retromolar space, mesiodistal third molar crown width, gonial angle and eruption levels were measured. The space/third molar width in early adult subjects was smaller (p third molars erupted in case of enough space in both age groups (p third molar width ratio is more favorable in adult subjects. Gonial angle is not in correlation with the retromolar space/third molar width ratio.

  12. On the index of G-spaces

    International Nuclear Information System (INIS)

    Volovikov, A Yu

    2000-01-01

    With a G-space, where G is a compact Lie group, one can associate an ideal in the cohomology ring of the classifying space for G. It is called the ideal-valued index of the G-space. A filtration of the ideal-valued index that arises in a natural way from the Leray spectral sequence is considered. Properties of the index with filtration are studied and numerical indices are introduced. These indices are convenient for estimates of the G-category and the study of the set of critical points of a G-invariant functional defined on a manifold. A generalization of the Bourgin-Yang theorem for the index with filtration is proved. This result is used for estimates of the index of the space of partial coincidences for a map of a space with p-torus action in a Euclidean space

  13. An unusual methylene aziridine refined in P2(1)/c and the nonstandard setting P2(1)/n.

    Science.gov (United States)

    Feast, George C; Haestier, James; Page, Lee W; Robertson, Jeremy; Thompson, Amber L; Watkin, David J

    2009-12-01

    The unusual methylene aziridine 6-tert-butyl-3-oxa-2-thia-1-azabicyclo[5.1.0]oct-6-ene 2,2-dioxide, C(9)H(15)NO(3)S, was found to crystallize with two molecules in the asymmetric unit. The structure was solved in both the approximately orthogonal and the oblique settings of space group No. 14, viz. P2(1)/n and P2(1)/c, respectively. A comparison of these results clearly displayed an increase in the correlation between coordinates in the ac plane for the oblique cell. The increase in the corresponding covariances makes a significant contribution to the standard uncertainties of derived parameters, e.g. bond lengths. Since there is yet no CIF definition for the full variance-covariance matrix, there are clear advantages to reporting the structure in the nonstandard space-group setting.

  14. The short range effective interaction and the spectra of calcium isotopes in (f-p) space

    International Nuclear Information System (INIS)

    Qing-ying, Z.; Shen-wu, L.; Jian-xin, W.

    1986-01-01

    In this work, the authors use a new type of extremely short range interaction, the double delta interaction (DDI) to calculate the low-lying spectra of calcium isotopes /sup 41/Ca through /sup 48/Ca. The configuration space (f-p) includes configurations ( f/sub 7/2//sup n/ ) and ( f/sub 7/2//sup n-1/2p/sub 3/2/). The calculated energies are compared with experimental data for 75 levels. For comparison, they also use usual modified surface delta interaction (MSDI) to calculate the same spectra aforementioned. It is clear that the results calculated with DDI are better than with MSDI. Therefore, in the short-range effective interaction the addition of body delta force to the modified surface delta force may improve the agreement with experiment. The authors believe that the conclusion will not be changed if one enlarges the shell model space

  15. Harmonic analysis on symmetric spaces

    CERN Document Server

    Terras, Audrey

    This text explores the geometry and analysis of higher rank analogues of the symmetric spaces introduced in volume one. To illuminate both the parallels and differences of the higher rank theory, the space of positive matrices is treated in a manner mirroring that of the upper-half space in volume one. This concrete example furnishes motivation for the general theory of noncompact symmetric spaces, which is outlined in the final chapter. The book emphasizes motivation and comprehensibility, concrete examples and explicit computations (by pen and paper, and by computer), history, and, above all, applications in mathematics, statistics, physics, and engineering. The second edition includes new sections on Donald St. P. Richards’s central limit theorem for O(n)-invariant random variables on the symmetric space of GL(n, R), on random  matrix theory, and on advances in the theory of automorphic forms on arithmetic groups.

  16. New alkali metal diphosphates how materials to preserve the security of the environment: CsNaCu(P2O7), Rb2Cu(P2O7) and CsNaCo(P2O7) synthesis and crystal structure determination

    Science.gov (United States)

    Chernyatieva, Anastasiya; Filatova, Alyona; Spiridonova, Dariya; Krivovichev, Sergey

    2013-04-01

    In this work we describe preliminary results of the synthesis and of a crystal-chemical study of synthetic phosphates with transition metals. Due to the increasing requirements for environmental safety specialists from various industries, we are searching for sustainable forms of immobilization of hazardous waste during storage. We are also developing a component-based waste for new materials. In our continued exploratory synthesis of compounds containing transition-metals, we were able to produce the new diphosphate phases CsNaCu(P2O7), Rb2Cu(P2O7) and CsNaCo(P2O7). A crystal chemical study has allowed us to identify new phosphates. Crystals of CsNaCu(P2O7) (Phase 1) is orthorhombic, crystallizes in space group Pmn21, with a = 5.147(8), b = 15.126(2), c = 9.717(2) Å, V = 756.20 Å3, R1 = 0.066 and Rb2Cu(P2O7) (Phase 2) is orthorhombic as well, crystallizes in space group Pmcn, with a = 5.183(8), b = 10.096(1), c = 15.146(3) Å, V = 793.55 Å3, R1 = 0.063, they have been obtained by high-temperature reaction of RbNO3, CsNO3, Cu(NO3)2, NaOH and (NH4)4P2O7. Synthetic crystals of the phosphate of copper and rubidium were studied in detail by us on the structures of Rb2Cu(P2O7) and Rb2Cu3(P2O7)2 - new alkali metal copper diphosphates (CHERNYATIEVA et al., 2008). Here we report the synthesis, the structure and the properties of the title compounds and we compare these phases with the previously discovered K2CuP2O7 (ELMAADI et al., 1995) and CsNaMnP2O7 (HUANG et al., 1998). These structures crystallize in other space groups, although their structures are also based on 2-D layers, formed by P2O7 groups combined with polyhedra of the transition metals (CHERNYATIEVA et al., 2012). A crystal chemical study has allowed us to identify even new diphosphates CsNaCu(P2O7) (Phase 3). Crystals of CsNaCoP2O7 is monoclinic, space group P 21/n, with a = 7,424(2), b = 7,648(1), c = 12,931(3)Å, β = 90,71(2)° , V = 734.2(3) Å3 and R1 = 0.060. The structure is based framework of Co

  17. Creating social spaces to tackle AIDS-related stigma: reviewing the role of church groups in Sub-Saharan Africa.

    Science.gov (United States)

    Campbell, C; Skovdal, M; Gibbs, A

    2011-08-01

    An expanding body of literature explores the role of African church groups in facilitating or hindering the support of people living with AIDS and challenging or contributing to HIV/AIDS-related stigma. Treating church groups as social spaces in which HIV/AIDS-related stigma may potentially be challenged, we systematically review this literature, identifying five themes that highlight the complex and contradictory role of the church as a potential agent of health-enhancing social change. In many ways the church perpetuates HIV/AIDS-related stigma through (i) moralistic attitudes and (ii) its reinforcement of conservative gender ideologies. However some churches have managed move towards action that makes a more positive contribution to HIV/AIDS management through (iii) promoting various forms of social control for HIV prevention, (iv) contributing to the care and support of the AIDS-affected and (v) providing social spaces for challenging stigmatising ideas and practices. We conclude that church groups, including church leadership, can play a key role in facilitating or hindering the creation of supportive social spaces to challenge stigma. Much work remains to be done in developing deeper understandings of the multi-layered factors that enable some churches, but not others, to respond effectively to HIV/AIDS.

  18. 基于MUSIC-Group Delay算法的相邻相干信号源定位%Closely spaced coherent-source localization based on MUSIC-group delay algorithm

    Institute of Scientific and Technical Information of China (English)

    郑家芝

    2016-01-01

    为了准确的进行相邻的相干信号源定位,提出了一种基于多重信号分类群延迟(MUSIC-group delay)的改进算法。首先,将空间平滑技术引入到波达方向(DoA)估计当中去除部分相干信号。由于在信号源相邻的情况下子空间算法的性能降低,就结合了 MUSIC-Group Delay算法来区分相邻的信号源,这种方法因为自身的加和性通过 MUSIC 相位谱来计算群延迟函数,从而能估计出相邻的信号源。理论分析和仿真结果表明提出的方法估计相邻的相干信号源比子空间算法更精确,分辨率更高。%In this paper,the closely spaced coherent-source localization is considered,and an improved method based on the group delay of Multiple Signal Classification (MUSIC)is presented.Firstly,we introduce the spatial smoothing technique into direction of arrival (DoA)estimation to get rid of the coherent part of signals.Due to the degraded per-formance of sub-space based methods on the condition of nearby sources,we then utilize the MUSIC-Group Delay algo-rithm to distinguish the closely spaced sources,which can resolve spatially close sources by the use of the group delay function computed from the MUSIC phase spectrum for efficient DoA estimation owing to its spatial additive property. Theoretical analysis and simulation results demonstrate that the proposed approach can estimate the DoA of the coherent close signal sources more precisely and have higher resolution compared with sub-space based methods.

  19. Group vector space method for estimating enthalpy of vaporization of organic compounds at the normal boiling point.

    Science.gov (United States)

    Wenying, Wei; Jinyu, Han; Wen, Xu

    2004-01-01

    The specific position of a group in the molecule has been considered, and a group vector space method for estimating enthalpy of vaporization at the normal boiling point of organic compounds has been developed. Expression for enthalpy of vaporization Delta(vap)H(T(b)) has been established and numerical values of relative group parameters obtained. The average percent deviation of estimation of Delta(vap)H(T(b)) is 1.16, which show that the present method demonstrates significant improvement in applicability to predict the enthalpy of vaporization at the normal boiling point, compared the conventional group methods.

  20. Export of Cytochrome P450 105D1 to the Periplasmic Space of Escherichia coli

    OpenAIRE

    Kaderbhai, Mustak A.; Ugochukwu, Cynthia C.; Kelly, Steven L.; Lamb, David C.

    2001-01-01

    CYP105D1, a cytochrome P450 from Streptomyces griseus, was appended at its amino terminus to the secretory signal of Escherichia coli alkaline phosphatase and placed under the transcriptional control of the native phoA promoter. Heterologous expression in E. coli phosphate-limited medium resulted in abundant synthesis of recombinant CYP105D1 that was translocated across the bacterial inner membrane and processed to yield authentic, heme-incorporated P450 within the periplasmic space. Cell ext...

  1. Knot wormholes and the dimensional invariant of exceptional Lie groups and Stein space hierarchies

    International Nuclear Information System (INIS)

    Elokaby, Ayman

    2009-01-01

    The present short note points out a most interesting and quite unexpected connection between the number of distinct knot as a function of their crossing number and exceptional Lie groups and Stein space hierarchies. It is found that the crossing number 7 plays the role of threshold similar to 4 and 5 in E-infinity theory and for the 11 crossing the number of distinct knots is very close to 4α-bar 0 +1=548+1=549, where α-bar 0 =137 is the inverse integer electromagnetic fine structure constant. This is particularly intriguing in view of a similar relation pertinent to the 17 two and three Stein spaces where the total dimension is Σ 1 17 Stein=5α-bar 0 +1=685+1=686, as well as the sum of the eight exceptional Lie symmetry groups Σ i=1 8 |E i |=4α-bar 0 =548. The slight discrepancy of one is explained in both cases by the inclusion of El Naschie's transfinite corrections leading to Σ i=1 8 |E i |=(4)(137+k 0 )=548.328157 and Σ i=1 17 Stein=(5)(137+k 0 )=685.41097, where k o = φ 5 (1 - φ 5 ) and φ=(√(5)-1)/2.

  2. The reaction of TcCl3(Me2PhP)3 with dithio ligands. Synthesis, characterization and X-ray crystal structures of [TcCl2(Me2PhP)2(Me2dtp)]and [Tc(Me2PhP)(Etxan)3](Me2PhP=dimethylphenylphosphine, Me2dtp-=O,O'-dimethyldithiophosphate, Etxan-=ethylxanthate)

    International Nuclear Information System (INIS)

    Lorenz, B.; Schmidt, K.; Hiller, W.; Abram, U.; Huebener, R.

    1993-01-01

    Trichlorotris (dimethylphenylphosphine)technetium(III); [TcCl 3 (Me 2 PhP) 3 ], reacts with dithio ligands to form chelate complexes of different compositions and coordinations geometries. The reaction with ethylxanthate (Etxan - ) yields the diamagnetic seven-coordinate [Tc(Me 2 PhP)(Etxan) 3 ], which crystallizes monoclinic in the space group P2 2 /c with Z = 4 (a = 18.44(5), b = 9.2(1), c = 15.36(6) A, β = 104.3(2) ). The final R value is 0.029. The metal has a pentagonal-bipyramidal environment. With ammonium dimethyldithiophosphate, (NH 4 )Me 2 dtp, [TcCl 3 (Me 2 PhP) 3 ] forms the paramagnetic [TcCl 2 (Me 2 PhP) 2 (Me 2 dtp) in which the technetium atom has a distorted octahedral coordination sphere. The compound crystallizes orthorhombic, space group Pbcn, with Z = 4 (a = 16.20(1), b = 10.445(1), c 14.878(1)). The final R value is 0.031. The chloro ligands are in trans arrangement. (orig.)

  3. Geometric group theory

    CERN Document Server

    Druţu, Cornelia

    2018-01-01

    The key idea in geometric group theory is to study infinite groups by endowing them with a metric and treating them as geometric spaces. This applies to many groups naturally appearing in topology, geometry, and algebra, such as fundamental groups of manifolds, groups of matrices with integer coefficients, etc. The primary focus of this book is to cover the foundations of geometric group theory, including coarse topology, ultralimits and asymptotic cones, hyperbolic groups, isoperimetric inequalities, growth of groups, amenability, Kazhdan's Property (T) and the Haagerup property, as well as their characterizations in terms of group actions on median spaces and spaces with walls. The book contains proofs of several fundamental results of geometric group theory, such as Gromov's theorem on groups of polynomial growth, Tits's alternative, Stallings's theorem on ends of groups, Dunwoody's accessibility theorem, the Mostow Rigidity Theorem, and quasiisometric rigidity theorems of Tukia and Schwartz. This is the f...

  4. Space, time and group identity in Jubilees 8-9

    African Journals Online (AJOL)

    p1243322

    This paper investigates this change in communication strategy and ... his orientation towards and organisation of space, as revealed in his ideas ..... two versions of the same tradition or the parallel development of an older, .... In the case of Numbers Israel ... with its chronological system of jubilees and heavenly space.

  5. Classifying spaces with virtually cyclic stabilizers for linear groups

    DEFF Research Database (Denmark)

    Degrijse, Dieter Dries; Köhl, Ralf; Petrosyan, Nansen

    2015-01-01

    We show that every discrete subgroup of GL(n, ℝ) admits a finite-dimensional classifying space with virtually cyclic stabilizers. Applying our methods to SL(3, ℤ), we obtain a four-dimensional classifying space with virtually cyclic stabilizers and a decomposition of the algebraic K-theory of its...

  6. F-door spaces and F-submaximal spaces

    Directory of Open Access Journals (Sweden)

    Lobna Dridi

    2013-04-01

    Full Text Available Submaximal spaces and door spaces play an enigmatic role in topology. In this paper, reinforcing this role, we are concerned with reaching two main goals: The first one is to characterize topological spaces X such that F(X is a submaximal space (resp., door space for some covariant functor Ff rom the category Top to itself. T0, and FH functors are completely studied. Secondly, our interest is directed towards the characterization of maps f given by a flow (X, f in the category Set, such that (X,P(f is submaximal (resp., door where P(f is a topology on X whose closed sets are exactly the f-invariant sets.

  7. Smile attractiveness related to buccal corridor space in 3 different facial types: A perception of 3 ethnic groups of Malaysians.

    Science.gov (United States)

    Nimbalkar, Smita; Oh, Yih Y; Mok, Reei Y; Tioh, Jing Y; Yew, Kai J; Patil, Pravinkumar G

    2018-03-16

    Buccal corridor space and its variations greatly influence smile attractiveness. Facial types are different for different ethnic populations, and so is smile attractiveness. The subjective perception of smile attractiveness of different populations may vary in regard to different buccal corridor spaces and facial patterns. The purpose of this study was to determine esthetic perceptions of the Malaysian population regarding the width of buccal corridor spaces and their effect on smile esthetics in individuals with short, normal, and long faces. The image of a smiling individual with a mesofacial face was modified to create 2 different facial types (brachyfacial and dolicofacial). Each face form was further modified into 5 different buccal corridors (2%, 10%, 15%, 22%, and 28%). The images were submitted to 3 different ethnic groups of evaluators (Chinese, Malay, Indian; 100 each), ranging between 17 and 21 years of age. A visual analog scale (50 mm in length) was used for assessment. The scores given to each image were compared with the Kruskal-Wallis test, and pairwise comparison was performed using the Mann-Whitney U test (α=.05). All 3 groups of evaluators could distinguish gradations of dark spaces in the buccal corridor at 2%, 10%, and 28%. Statistically significant differences were observed among 3 groups of evaluators in esthetic perception when pairwise comparisons were performed. A 15% buccal corridor was found to score esthetically equally within 3 face types by all 3 groups of evaluators. The Indian population was more critical in evaluation than the Chinese or Malay populations. In a pairwise comparison, more significant differences were found between long and short faces and the normal face; the normal face was compared with long and short faces separately. The width of the buccal corridor space influences smile attractiveness in different facial types. A medium buccal corridor (15%) is the esthetic characteristic preferred by all groups of evaluators

  8. Experimental and computational studies on creatininium 4-nitrobenzoate - An organic proton transfer complex

    Science.gov (United States)

    Thirumurugan, R.; Anitha, K.

    2017-10-01

    A new organic proton transfer complex of creatininium 4-nitrobenzoate (C4NB) has been synthesized and its single crystals were grown successfully by slow evaporation technique. The grown single crystal was subjected to various characterization techniques like single crystal X-ray diffraction (SCXRD), FTIR, FT-Raman and Kurtz-Perry powder second harmonic generation (SHG). The SCXRD analysis revealed that C4NB was crystallized into orthorhombic crystal system, with noncentrosymmetric (NCS), P212121 space group. The creatininium cation and 4-nitrobenzoate anion were connected through a pair of N__H⋯O hydrogen bonds (N(3)__H(6) ⋯ O(3) (x+1, y, z) and N(2)__H(5) &ctdot O(2) (x-1/2, -y-1/2, -z+2)) and fashioned a R22(8) ring motif. The crystal structure was stabilized by strong N__H⋯O and weak C__H⋯O intermolecular interactions and it was quantitatively analysed by Hirshfeld surface and fingerprint (FP) analysis. FTIR and FT-Raman studies confirmed the vibrational modes of functional groups present in C4NB compound indubitably. SHG efficiency of grown crystal was 4.6 times greater than that of standard potassium dihydrogen phosphate (KDP) material. Moreover, density functional theory (DFT) studies such as Mulliken charge distribution, frontier molecular orbitals (FMOs), molecular electrostatic potential (MEP) map, natural bond orbital analysis (NBO) and first order hyperpolarizability (β0) were calculated to explore the structure-property relationship.

  9. The effect of additional dead space on respiratory exchange ratio and carbon dioxide production due to training.

    Science.gov (United States)

    Smolka, Lukasz; Borkowski, Jacek; Zaton, Marek

    2014-01-01

    The purpose of the study was to investigate the effects of implementing additional respiratory dead space during cycloergometry-based aerobic training. The primary outcome measures were respiratory exchange ratio (RER) and carbon dioxide production (VCO2). Two groups of young healthy males: Experimental (Exp, n = 15) and Control (Con, n = 15), participated in this study. The training consisted of 12 sessions, performed twice a week for 6 weeks. A single training session consisted of continuous, constant-rate exercise on a cycle ergometer at 60% of VO2max which was maintained for 30 minutes. Subjects in Exp group were breathing through additional respiratory dead space (1200ml), while subjects in Con group were breathing without additional dead space. Pre-test and two post-training incremental exercise tests were performed for the detection of gas exchange variables. In all training sessions, pCO2 was higher and blood pH was lower in the Exp group (p exchange ratio and carbon dioxide production.In all training sessions, respiratory acidosis was gained by experimental group only.No significant difference in RER and VCO2 between experimental and control group due to the trainings.The lack of difference in post-training values of RER and VCO2 between groups means absence of inhibition in glycolysis and glycogenolysis during exercise with additional dead space.

  10. WORKSHOP: Inner space - outer space

    International Nuclear Information System (INIS)

    Anon.

    1984-01-01

    During the first week of May, the Fermilab theoretical astrophysics group hosted an international conference on science at the interface of particle physics and cosmology/astrophysics. The conference (Inner Space-Outer Space) was attended by a very diverse group of more than 200 physical scientists, including astronomers, astrophysicists, cosmologists, low-temperature physicists, and elementary particle theorists and experimentalists. The common interest which brought this diverse group to gether is the connection between physics on the smallest scale probed by man - the realm of elementary particle physics - and physics on the largest scale imaginable (the entire Universe) - the realm of cosmology

  11. WORKSHOP: Inner space - outer space

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1984-09-15

    During the first week of May, the Fermilab theoretical astrophysics group hosted an international conference on science at the interface of particle physics and cosmology/astrophysics. The conference (Inner Space-Outer Space) was attended by a very diverse group of more than 200 physical scientists, including astronomers, astrophysicists, cosmologists, low-temperature physicists, and elementary particle theorists and experimentalists. The common interest which brought this diverse group to gether is the connection between physics on the smallest scale probed by man - the realm of elementary particle physics - and physics on the largest scale imaginable (the entire Universe) - the realm of cosmology.

  12. A generalized Wigner function on the space of irreducible representations of the Weyl-Heisenberg group and its transformation properties

    International Nuclear Information System (INIS)

    Ibort, A; Man'ko, V I; Marmo, G; Simoni, A; Ventriglia, F

    2009-01-01

    A natural extension of the Wigner function to the space of irreducible unitary representations of the Weyl-Heisenberg group is discussed. The action of the automorphisms group of the Weyl-Heisenberg group onto Wigner functions and their generalizations and onto symplectic tomograms is elucidated. Some examples of physical systems are considered to illustrate some aspects of the characterization of the Wigner functions as solutions of differential equations

  13. A randomized controlled trial of group Stepping Stones Triple P: a mixed-disability trial.

    Science.gov (United States)

    Roux, Gemma; Sofronoff, Kate; Sanders, Matthew

    2013-09-01

    Stepping Stones Triple P (SSTP) is a parenting program designed for families of a child with a disability. The current study involved a randomized controlled trial of Group Stepping Stones Triple P (GSSTP) for a mixed-disability group. Participants were 52 families of children diagnosed with an Autism Spectrum Disorder, Down syndrome, Cerebral Palsy, or an intellectual disability. The results demonstrated significant improvements in parent-reported child behavior, parenting styles, parental satisfaction, and conflict about parenting. Results among participants were similar despite children's differing impairments. The intervention effect was maintained at 6-month follow-up. The results indicate that GSSTP is a promising intervention for a mixed-disability group. Limitations of the study, along with areas for future research, are also discussed. © FPI, Inc.

  14. Location preferences of groups in public leisure spaces: the case of Likya Cafe in Ankara

    OpenAIRE

    Altay, Can

    1999-01-01

    Ankara : Department of Interior Architecture and Environmental Design and Institute of Economics and Social Sciences, Bilkent Univ., 1999. Thesis (Master's) -- Bilkent University, 1999. Includes bibliographical references. In this study, public leisure spaces are examined considering the social and spatial behavior of occupant groups. After an introduction to the concepts of leisure, its types, its relations with public life and cultural concepts, the study discusses leisure ...

  15. Groups on transformations in Finslerian spaces

    International Nuclear Information System (INIS)

    Misra, R.B.

    1993-01-01

    The article first appeared in the Internal Reports of the ICTP in 1981. Since then the topic has attracted a large number of authors and several contributions have been made thereafter. Thus, a previous work of the author is revised and up-dated here including the post-1981 contributions in the field. Infinitesimal transformations defining motions, affine motions, projective motions, conformal transformations and curvature collineations in various types of Finslerian spaces are discussed here. The notation and symbolism used in the paper is mainly based on the author's works. (author). 72 refs

  16. Realizing spaces as path-component spaces

    OpenAIRE

    Banakh, Taras; Brazas, Jeremy

    2018-01-01

    The path component space of a topological space $X$ is the quotient space $\\pi_0(X)$ whose points are the path components of $X$. We show that every Tychonoff space $X$ is the path-component space of a Tychonoff space $Y$ of weight $w(Y)=w(X)$ such that the natural quotient map $Y\\to \\pi_0(Y)=X$ is a perfect map. Hence, many topological properties of $X$ transfer to $Y$. We apply this result to construct a compact space $X\\subset \\mathbb{R}^3$ for which the fundamental group $\\pi_1(X,x_0)$ is...

  17. Compactness of the automorphism group of a topological parallelism on real projective 3-space: The disconnected case

    OpenAIRE

    Rainer, Löwen

    2017-01-01

    We prove that the automorphism group of a topological parallelism on real projective 3-space is compact. In a preceding article it was proved that at least the connected component of the identity is compact. The present proof does not depend on that earlier result.

  18. Lattice location of the group V elements Sb, As, and P in ZnO

    CERN Document Server

    Wahl, Ulrich; Mendonça, Tânia; Decoster, Stefan

    2010-01-01

    Modifying the properties of ZnO by means of incorporating antimony, arsenic or phosphorus impurities is of interest since these group V elements have been reported in the literature among the few successful p-type dopants in this technologically promising II-VI compound. The lattice location of ion-implanted Sb, As, and P in ZnO single crystals was investigated by means of the electron emission channeling technique using the radioactive isotopes $^{124}$Sb, $^{73}$As and $^{33}$P and it is found that they preferentially occupy substitutional Zn sites while the possible fractions on substitutional O sites are a few percent at maximum. The lattice site preference is understandable from the relatively large ionic size of the heavy mass group V elements. Unfortunately the presented results cannot finally settle the interesting issue whether substitutional Sb, As or P on oxygen sites or Sb$_{Zn}$−2V$_{Zn}$, As$_{Zn}$−2V$_{Zn}$ or P$_{Zn}$−2V$_{Zn}$ complexes (as suggested in the literature) are responsible f...

  19. Through space and through bridge channels of charge transfer at p-n nano-junctions: A DFT study

    Energy Technology Data Exchange (ETDEWEB)

    Dandu, Naveen [Department of Chemistry and Biochemistry, NDSU, Fargo, ND 58108 (United States); Tretiak, Sergei [Theoretical Division, Center for Nonlinear Studies (CNLS) and Center for Integrated Nanotechnologies (CINT), Los Alamos National Laboratory, Los Alamos, 57069, NM 87454 (United States); Kilina, Svetlana [Department of Chemistry and Biochemistry, NDSU, Fargo, ND 58108 (United States); Kilin, Dmitri, E-mail: Dmitri.Kilin@ndsu.edu [Department of Chemistry and Biochemistry, NDSU, Fargo, ND 58108 (United States)

    2016-12-20

    Highlights: • Properties of interacting QDs depend on the fashion of interaction: through-bond or through-space. • The disconnected and undoped dimer models shows FÓ§rster band formation. • Dimer models with some doping exhibit degenerate charge-transfer excitons. • p- and n-doped qds shows polarization at the interface. • A photoexcitation polarizes p-n interface, in relation to phototovoltaic effect. - Abstract: Details of charge density distribution at p-n nano interface are analyzed with density functional theory techniques using model system of dimers of doped silicon quantum dots interacting through bond and through space. Spatial distributions of transition densities between the ground and excited states suggest the character of essential electronic excitations, which have a FÓ§rster, bound, unbound, or charge transfer character. A redistribution of electronic density from n-impurities to p-impurities results in a ground state polarization and creates an offset of energies of the bands localized on p-doped quantum dot and the bands localized on n-doped quantum dot. Although impurities contribute very few orbitals to the total density, a ground state charge redistribution and polarization are both responsible for the presence of a large number of charge transfer excitations involving solely silicon orbitals.

  20. Bootstrap percolation: a renormalisation group approach

    International Nuclear Information System (INIS)

    Branco, N.S.; Santos, Raimundo R. dos; Queiroz, S.L.A. de.

    1984-02-01

    In bootstrap percolation, sites are occupied at random with probability p, but each site is considered active only if at least m of its neighbours are also active. Within an approximate position-space renormalization group framework on a square lattice we obtain the behaviour of the critical concentration p (sub)c and of the critical exponents ν and β for m = 0 (ordinary percolation), 1,2 and 3. We find that the bootstrap percolation problem can be cast into different universality classes, characterized by the values of m. (author) [pt

  1. The normal holonomy group

    International Nuclear Information System (INIS)

    Olmos, C.

    1990-05-01

    The restricted holonomy group of a Riemannian manifold is a compact Lie group and its representation on the tangent space is a product of irreducible representations and a trivial one. Each one of the non-trivial factors is either an orthogonal representation of a connected compact Lie group which acts transitively on the unit sphere or it is the isotropy representation of a single Riemannian symmetric space of rank ≥ 2. We prove that, all these properties are also true for the representation on the normal space of the restricted normal holonomy group of any submanifold of a space of constant curvature. 4 refs

  2. Estimation of surface Latent Heat Fluxes from IRS-P4/MSMR ...

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging Solutions)

    IRS-P4/MSMR satellite data. Randhir Singh, B Simon and P C Joshi. Atmospheric Sciences Division, Meteorology & Oceanography Group, Space Applications Centre, ISRO. Ahmedabad 380 015, India. The brightness temperatures of the Microwave sensor MSMR (Multichannel Scanning Microwave. Radiometer) launched ...

  3. Multiprobe characterization of plasma flows for space propulsion

    NARCIS (Netherlands)

    Damba, Julius; Argente, P.; Maldonado, P. E.; Cervone, A.; Domenech-Garret, J.L.; Conde, Luis

    2018-01-01

    <p>Plasma engines for space propulsion generate plasma jets (also denominated plasma plumes) having supersonic ion groups with typical speeds in the order of tens of kilometers per second, which lies between electron and ion thermal speeds. Studies of the stationary plasma expansion process using a

  4. Group dynamics in a long-term blind endeavor on Earth: An analog for space missions (Lewis & Clark Expedition group dynamic analysis)

    Science.gov (United States)

    Allner, M.; Rygalov, V.

    2008-12-01

    suggested distinguishable mission phase model, the Lewis and Clark Expedition will be analyzed for similarities to these space findings. Factors of consideration in support of this analysis involve an understanding of the leadership qualities of Lewis and Clark (and relations established and maintained with one another), the selection and diversity of their crew, and the group dynamics that were developed and maintained so carefully during the expedition. With this knowledge and understanding one can gain enormous insights useful in the planning and preparation for future long-duration space exploratory missions with high level of autonomy, mobility, minimal primary life support supply and high dependence on material re-circulation and In-Situ Resource Utilization approach.

  5. The fundamental groupoid of the quotient of a Hausdorff space by a discontinuous action of a discrete group is the orbit groupoid of the induced action

    OpenAIRE

    Brown, Ronald; Higgins, Philip J.

    2002-01-01

    The main result is that the fundamental groupoid of the orbit space of a discontinuous action of a discrete group on a Hausdorff space which admits a universal cover is the orbit groupoid of the fundamental groupoid of the space. We also describe work of Higgins and of Taylor which makes this result usable for calculations. As an example, we compute the fundamental group of the symmetric square of a space. The main result, which is related to work of Armstrong, is due to Brown and Higgins in ...

  6. Picard-Fuchs equations and the moduli space of superconformal field theories

    International Nuclear Information System (INIS)

    Cadavid, A.C.; Ferrara, S.

    1991-01-01

    We derive simple techniques which allow us to relate Picard-Fuchs differential equations for the periods of holomorphic p-forms on certain complex manifolds, to their moduli space and its modular group (target space duality). For Calabi-Yau manifolds the special geometry of moduli space gives the Zamolodchikov metric and the Yukawa couplings in terms of the periods. For general N=2 superconformal theories these equations exactly determine perturbed correlation functions of the chiral rings of primary fields. (orig.)

  7. Quantum groups, roots of unity and particles on quantized Anti-de Sitter space

    International Nuclear Information System (INIS)

    Steinacker, H.

    1997-01-01

    Quantum groups in general and the quantum Anti-de Sitter group U q (so(2,3)) in particular are studied from the point of view of quantum field theory. The author shows that if q is a suitable root of unity, there exist finite-dimensional, unitary representations corresponding to essentially all the classical one-particle representations with (half) integer spin, with the same structure at low energies as in the classical case. In the massless case for spin ≥ 1, open-quotes naiveclose quotes representations are unitarizable only after factoring out a subspace of open-quotes pure gaugesclose quotes, as classically. Unitary many-particle representations are defined, with the correct classical limit. Furthermore, the author identifies a remarkable element Q in the center of U q (g), which plays the role of a BRST operator in the case of U q (so(2,3)) at roots of unity, for any spin ≥ 1. The associated ghosts are an intrinsic part of the indecomposable representations. The author shows how to define an involution on algebras of creation and anihilation operators at roots of unity, in an example corresponding to non-identical particles. It is shown how nonabelian gauge fields appear naturally in this framework, without having to define connections on fiber bundles. Integration on Quantum Euclidean space and sphere and on Anti-de Sitter space is studied as well. The author gives a conjecture how Q can be used in general to analyze the structure of indecomposable representations, and to define a new, completely reducible associative (tensor) product of representations at roots of unity, which generalizes the standard open-quotes truncatedclose quotes tensor product as well as many-particle representations

  8. Quantum groups, roots of unity and particles on quantized Anti-de Sitter space

    Energy Technology Data Exchange (ETDEWEB)

    Steinacker, Harold [Univ. of California, Berkeley, CA (United States). Dept. of Physics

    1997-05-23

    Quantum groups in general and the quantum Anti-de Sitter group Uq(so(2,3)) in particular are studied from the point of view of quantum field theory. The author shows that if q is a suitable root of unity, there exist finite-dimensional, unitary representations corresponding to essentially all the classical one-particle representations with (half) integer spin, with the same structure at low energies as in the classical case. In the massless case for spin ≥ 1, "naive" representations are unitarizable only after factoring out a subspace of "pure gauges", as classically. Unitary many-particle representations are defined, with the correct classical limit. Furthermore, the author identifies a remarkable element Q in the center of Uq(g), which plays the role of a BRST operator in the case of Uq(so(2,3)) at roots of unity, for any spin ≥ 1. The associated ghosts are an intrinsic part of the indecomposable representations. The author shows how to define an involution on algebras of creation and anihilation operators at roots of unity, in an example corresponding to non-identical particles. It is shown how nonabelian gauge fields appear naturally in this framework, without having to define connections on fiber bundles. Integration on Quantum Euclidean space and sphere and on Anti-de Sitter space is studied as well. The author gives a conjecture how Q can be used in general to analyze the structure of indecomposable representations, and to define a new, completely reducible associative (tensor) product of representations at roots of unity, which generalizes the standard "truncated" tensor product as well as many-particle representations.

  9. BOX-PCR-based identification of bacterial species belonging to Pseudomonas syringae: P. viridiflava group

    Directory of Open Access Journals (Sweden)

    Abi S.A. Marques

    2008-01-01

    Full Text Available The phenotypic characteristics and genetic fingerprints of a collection of 120 bacterial strains, belonging to Pseudomonas syringae sensu lato group, P. viridiflava and reference bacteria were evaluated, with the aim of species identification. The numerical analysis of 119 nutritional characteristics did not show patterns that would help with identification. Regarding the genetic fingerprinting, the results of the present study supported the observation that BOX-PCR seems to be able to identify bacterial strains at species level. After numerical analyses of the bar-codes, all pathovars belonging to each one of the nine described genomospecies were clustered together at a distance of 0.72, and could be separated at genomic species level. Two P. syringae strains of unknown pathovars (CFBP 3650 and CFBP 3662 and the three P. syringae pv. actinidiae strains were grouped in two extra clusters and might eventually constitute two new species. This genomic species clustering was particularly evident for genomospecies 4, which gathered P. syringae pvs. atropurpurea, coronafaciens, garçae, oryzae, porri, striafaciens, and zizaniae at a noticeably low distance.

  10. Phylogenetic relationships and biogeography of Ptilophora (Gelidiales, Rhodophyta) with descriptions of P. aureolusa, P. malagasya, and P. spongiophila from Madagascar.

    Science.gov (United States)

    Boo, Ga Hun; Gall, Line Le; Hwang, Il Ki; Miller, Kathy Ann; Boo, Sung Min

    2018-04-01

    The genus Ptilophora currently includes 16 species occurring mostly in subtidal habitats of the Indo-Pacific Ocean, but its global diversity and biogeography are poorly understood. We analyzed mitochondrial cox1, plastid rbcL and plastid psbA sequences from specimens collected in southern Madagascar during the 2010 Atimo Vatae expedition and studied their morphologies. Both morphological and molecular data sets demonstrated the presence of five species in southern Madagascar: Ptilophora hildebrandtii, P. pterocladioides, and three new species described here, P. aureolusa, P. malagasya, and P. spongiophila. Ptilophora aureolusa is distinguished by its compound pinnae with uniformly spaced pinnules. Ptilophora malagasya has an indistinct midrib and irregularly spaced pinnules. Ptilophora spongiophila, heavily coated with sponges, has cylindrical to flattened main axes, lateral and surface proliferations, and spatulate tetrasporangial sori. The species of Ptilophora found in Madagascar are endemic, except P. hildebrandtii, which also occurs in eastern Africa. Ptilophora comprises four phylogenetic groups that map to eastern Australia, Japan, western Australia/Southeast Asia/Madagascar/eastern Africa, and Madagascar/eastern Africa/Aegean Sea. Biogeographical analysis revealed that the ancestor of Ptilophora originated in Australia, but most of the species radiated from Madagascar. © 2018 Phycological Society of America.

  11. "Friends" and "Foes" in the Social Space of the Tatar Ethnic Group

    Directory of Open Access Journals (Sweden)

    Nataliia O. Khazieva

    2017-10-01

    Full Text Available The history of the World Culture is a demonstration of the "war" between the two opposites: on the one hand, we see a trend towards unification of all aspects of life on a global scale, and on the other, there is a clear confrontation between different groups of mankind. Of the many causes of the disunity of the people, the authors' focus at the opposition "friend – foe" as a metaphysical principle of formation of social space wasn't chosen by accident. The fact is that any culture, in principle, is dichotomous, and the opposition "friend – foe" is the fullest incarnation of this dichotomy. As a universal principle of the formation and functioning of the cultures, it originally manifests itself in every one of them. And, as the authors of the study suggest: this opposition could either "work" in general on the cross-cultural cooperation and unity or be one of the confrontation sources. The main result of the study is that history has prepared and put forward the Tartars for carrying out a special mission, to unite peoples and cultures. But the revolutionary social upheavals that take place in the modern world pose a threat (in the circumstances of forced migration of peoples, the growth of national consciousness of the former Soviet Union space, and especially in the face of Islamic fundamentalism on fulfilling this function.

  12. Distribution of the minimum path on percolation clusters: A renormalization group calculation

    International Nuclear Information System (INIS)

    Hipsh, Lior.

    1993-06-01

    This thesis uses the renormalization group for the research of the chemical distance or the minimal path on percolation clusters on a 2 dimensional square lattice. Our aims are to calculate analytically (iterative calculation) the fractal dimension of the minimal path. d min. , and the distributions of the minimum paths, l min for different lattice sizes and for different starting densities (including the threshold value p c ). For the distributions. We seek for an analytic form which describes them. The probability to get a minimum path for each linear size L is calculated by iterating the distribution of l min for the basic cell of size 2*2 to the next scale sizes, using the H cell renormalization group. For the threshold value of p and for values near to p c . We confirm a scaling in the form: P(l,L) =f1/l(l/(L d min ). L - the linear size, l - the minimum path. The distribution can be also represented in the Fourier space, so we will try to solve the renormalization group equations in this space. A numerical fitting is produced and compared to existing numerical results. In order to improve the agreement between the renormalization group and the numerical simulations, we also present attempts to generalize the renormalization group by adding more parameters, e.g. correlations between bonds in different directions or finite densities for occupation of bonds and sites. (author) 17 refs

  13. p-topological Cauchy completions

    Directory of Open Access Journals (Sweden)

    J. Wig

    1999-01-01

    Full Text Available The duality between “regular” and “topological” as convergence space properties extends in a natural way to the more general properties “p-regular” and “p-topological.” Since earlier papers have investigated regular, p-regular, and topological Cauchy completions, we hereby initiate a study of p-topological Cauchy completions. A p-topological Cauchy space has a p-topological completion if and only if it is “cushioned,” meaning that each equivalence class of nonconvergent Cauchy filters contains a smallest filter. For a Cauchy space allowing a p-topological completion, it is shown that a certain class of Reed completions preserve the p-topological property, including the Wyler and Kowalsky completions, which are, respectively, the finest and the coarsest p-topological completions. However, not all p-topological completions are Reed completions. Several extension theorems for p-topological completions are obtained. The most interesting of these states that any Cauchy-continuous map between Cauchy spaces allowing p-topological and p′-topological completions, respectively, can always be extended to a θ-continuous map between any p-topological completion of the first space and any p′-topological completion of the second.

  14. Zeta-function regularization approach to finite temperature effects in Kaluza-Klein space-times

    International Nuclear Information System (INIS)

    Bytsenko, A.A.; Vanzo, L.; Zerbini, S.

    1992-01-01

    In the framework of heat-kernel approach to zeta-function regularization, in this paper the one-loop effective potential at finite temperature for scalar and spinor fields on Kaluza-Klein space-time of the form M p x M c n , where M p is p-dimensional Minkowski space-time is evaluated. In particular, when the compact manifold is M c n = H n /Γ, the Selberg tracer formula associated with discrete torsion-free group Γ of the n-dimensional Lobachevsky space H n is used. An explicit representation for the thermodynamic potential valid for arbitrary temperature is found. As a result a complete high temperature expansion is presented and the roles of zero modes and topological contributions is discussed

  15. Efficacy of the Positive Parenting Program (Triple-P for a Group of Parents of Children with Attention Deficit Hyperactivity Disorder (ADHD

    Directory of Open Access Journals (Sweden)

    Mehdi Tehranidoost

    2008-07-01

    Full Text Available "nObjective: To evaluate the efficacy of the Positive Parenting Program (Triple-P for parents of children with attention deficit hyperactivity disorder (ADHD. "nMethod:  Sixty families who had at least one child with clinically diagnosed ADHD aged between 6 to12 were recruited from the consecutive referrals to a child and adolescent psychiatric clinic. Families were randomly assigned to the intervention group (who participated in an 8- week- group Triple-P, N=30 and a control group (N=30. Parents completed the battery of self-report questionnaires of triple-P at the beginning and after the 8th session. "nResults: There were no significant differences in pre intervention measures between the two groups. Comparing the pre and post intervention data, the Triple- P group was associated with significantly lower levels of parent reported child behavior problems (P=0.001, lower levels of dysfunctional parenting (P=0.001 and greater parental competence (P=0.001 than the control group. The parents the in triple-P group had significant improvement on measures of depression, anxiety and stress, in comparison with the control group (P=0.001. This study did not follow the long term effect which marks its limitation. "nConclusion: The Triple-P program can be recommended for parents of children with ADHD to reduce the problem behavior of their children and to improve their abilities.

  16. Kent in space: Cosmic dust to space debris

    Science.gov (United States)

    McDonnell, J. A. M.

    1994-10-01

    The dusty heritage of the University of Kent's Space Group commenced at Jodrell Bank, Cheshire, U.K., the home of the largest steerable radio telescope. While Professor Bernard Lovell's 250 ft. diameter telescope was used to command the U.S. deep space Pioneer spacecraft, Professor Tony McDonnell, as a research student in 1960, was developing a space dust detector for the US-UK Ariel program. It was successful. With a Ph.D. safely under the belt, it seemed an inevitable step to go for the next higher degree, a B.T.A.] Two years with NASA at Goddard Space Flight Center, Greenbelt, provided excellent qualifications for such a graduation ('Been to America'). A spirited return to the University of Kent at Canterbury followed, to one of the green field UK University sites springing from the Robbins Report on Higher Education. Swimming against the current of the brain drain, and taking a very considerable reduction in salary, it was with some disappointment that he found that the UK Premier Harold Wilson's 'white-hot technological revolution' never quite seemed to materialize in terms of research funding] Research expertise, centered initially on cosmic dust, enlarged to encompass planetology during the Apollo program, and rightly acquired international acclaim, notching up a history of space missions over 25 years. The group now comprises 38 people supported by four sources: the government's Research Councils, the University, the Space Agencies and Industry. This paper describes the thrust of the group's Research Plan in Space Science and Planetology; not so much based on existing international space missions, but more helping to shape the direction and selection of space missions ahead.

  17. Local Backbone Flexibility as a Determinant of the Apparent pKa Values of Buried Ionizable Groups in Proteins.

    Science.gov (United States)

    Peck, Meredith T; Ortega, Gabriel; De Luca-Johnson, Javier N; Schlessman, Jamie L; Robinson, Aaron C; García-Moreno E, Bertrand

    2017-10-10

    Ionizable groups buried in the hydrophobic interior of proteins are essential for energy transduction. These groups can have highly anomalous pK a values that reflect the incompatibility between charges and dehydrated environments. A systematic study of pK a values of buried ionizable groups in staphylococcal nuclease (SNase) suggests that these pK a values are determined in part by conformational reorganization of the protein. Lys-66 is one of the most deeply buried residues in SNase. We show that its apparent pK a of 5.7 reflects the average of the pK a values of Lys-66 in different conformational states of the protein. In the fully folded state, Lys-66 is deeply buried in the hydrophobic core of SNase and must titrate with a pK a of ≪5.7. In other states, the side chain of Lys-66 is fully solvent-exposed and has a normal pK a of ≈10.4. We show that the pK a of Lys-66 can be shifted from 5.7 toward a more normal value of 7.1 via the insertion of flanking Gly residues at positions 64 and 67 to promote an "open" conformation of SNase. Crystal structures and nuclear magnetic resonance spectroscopy show that in these Gly-containing variants Lys-66 can access bulk water as a consequence of overwinding of the C-terminal end of helix 1. These data illustrate that the apparent pK a values of buried groups in proteins are governed in part by the difference in free energy between different conformational states of the protein and by differences in the pK a values of the buried groups in the different conformations.

  18. Pseudomonas putida and Pseudomonas fluorescens Species Group Recovery from Human Homes Varies Seasonally and by Environment.

    Directory of Open Access Journals (Sweden)

    Susanna K Remold

    Full Text Available By shedding light on variation in time as well as in space, long-term biogeographic studies can help us define organisms' distribution patterns and understand their underlying drivers. Here we examine distributions of Pseudomonas in and around 15 human homes, focusing on the P. putida and P. fluorescens species groups. We describe recovery from 10,941 samples collected during up to 8 visits per home, occurring on average 2.6 times per year. We collected a mean of 141 samples per visit, from sites in most rooms of the house, from the surrounding yards, and from human and pet occupants. We recovered Pseudomonas in 9.7% of samples, with the majority of isolates being from the P. putida and P. fluorescens species groups (approximately 62% and 23% of Pseudomonas samples recovered respectively. Although representatives of both groups were recovered from every season, every house, and every type of environment sampled, recovery was highly variable across houses and samplings. Whereas recovery of P. putida group was higher in summer and fall than in winter and spring, P. fluorescens group isolates were most often recovered in spring. P. putida group recovery from soils was substantially higher than its recovery from all other environment types, while higher P. fluorescens group recovery from soils than from other sites was much less pronounced. Both species groups were recovered from skin and upper respiratory tract samples from healthy humans and pets, although this occurred infrequently. This study indicates that even species that are able to survive under a broad range of conditions can be rare and variable in their distributions in space and in time. For such groups, determining patterns and causes of stochastic and seasonal variability may be more important for understanding the processes driving their biogeography than the identity of the types of environments in which they can be found.

  19. Invariant subspaces in some function spaces on symmetric spaces. II

    International Nuclear Information System (INIS)

    Platonov, S S

    1998-01-01

    Let G be a semisimple connected Lie group with finite centre, K a maximal compact subgroup of G, and M=G/K a Riemannian symmetric space of non-compact type. We study the problem of describing the structure of closed linear subspaces in various function spaces on M that are invariant under the quasiregular representation of the group G. We consider the case when M is a symplectic symmetric space of rank 1

  20. Managing the space sciences

    Science.gov (United States)

    1995-01-01

    In April 1994 the National Research Council received a request from NASA that the NRC's Space Studies Board provide guidance on questions relating to the management of NASA's programs in the space sciences. The issues raised in the request closely reflect questions posed in the agency's fiscal year 1994 Senate appropriations report. These questions included the following: Should all the NASA space science programs be gathered into a 'National Institute for Space Science'? What other organizational changes might be made to improve the coordination and oversight of NASA space science programs? What processes should be used for establishing interdisciplinary science priorities based on scientific merit and other criteria, while ensuring opportunities for newer fields and disciplines to emerge? And what steps could be taken to improve utilization of advanced technologies in future space scienc missions? This report details the findings of the Committee on the Future of Space Science (FOSS) and its three task groups: the Task Group on Alternative Organizations, Task Group on Research Prioritization, and the Task Group on Technology.

  1. Social Practice in the Public Space. Uses Beyond the Social Norms and the Design of Space Prácticas sociales en el espacio público. Usos que sobrepasan las normas y el diseño del espacio

    Directory of Open Access Journals (Sweden)

    Luz Dary Ríos

    2012-05-01

    Full Text Available <p>This paper aims at presenting people’s practices in the urban public space of Barcelona. It is about the way people find their space in places through its use. In other words, it describes the way people make relationships and links between each other and the urban space.

    >We present a qualitative study from an ethnographic approach. It identifies three basic types of practices associated with the urban space: one type practice was connected to the work concept, another one to the idea of transit, and the last type to the tourists practice.  These urban social practices show that the public space is used in a different way than it was designed for because the designers make public space for other functions. The urban social practices are linked with psychosocial processes such as identity, social cohesion, social norms and mobility.p>>Furthermore, the practices presented in this investigation go beyond urban social law and the structure function of public space without altering coexistence and sociability.p>>En este artículo pretendemos describir  las prácticas sociales y urbanas de las personas en un espacio público, concretamente en la ciudad de Barcelona. Las personas, cuando usan el espacio público lo transforman en lugar, es decir, generan ciertas relaciones y vínculos  entre ellas y el espacio urbano, de tal forma que, éste,  se modifica paulatinamente.p> <p> p> <p>Para la descripción de esas prácticas sociales y urbanas utilizamos una metodología cualitativa, específicamente una etnografía. Se identificaron y se eligieron tres tipos básicos de prácticas asociadas al espacio urbano: un tipo de esas prácticas se relaciona con el concepto de trabajo, otro con la idea de transitar (movimiento y el último tipo con la práctica turística. Dichas prácticas sociales y urbanas evidenciaron el uso que llega a hacerse de los espacios públicos, uso que, la mayoría de las veces

  2. Group Dynamics as a Critical Component of Successful Space Exploration: Conceptual Theory and Insights from the Biosphere 2 Closure Experiment

    Science.gov (United States)

    Nelson, Mark; Allen, John P.

    As space exploration and eventually habitation achieves longer durations, successfully managing group dynamics of small, physically isolated groups will become vital. The paper summarizes important underlying research and conceptual theory and how these manifested in a well-documented example: the closure experiments of Biosphere 2. Key research breakthroughs in discerning the operation of small human groups comes from the pioneering work of W.R. Bion. He discovered two competing modalities of behavior. The first is the “task-oriented” or work group governed by shared acceptance of goals, reality-thinking in relation to time, resources and rational, and intelligent management of challenges presented. The opposing, usually unconscious, modality is what Bion called the “basic-assumption” group and alternates between three “group animal” groups: dependency/kill the leader; fight/flight and pairing. If not dealt with, these dynamics work to undermine and defeat the conscious task group’s goal achievement. The paper discusses crew training and selection, various approaches to structuring the work and hierarchy of the group, the importance of contact with a larger population through electronic communication and dealing with the “us-them” syndrome frequently observed between crew and Mission Control. The experience of the first two year closure of Biosphere 2 is drawn on in new ways to illustrate vicissitudes and management of group dynamics especially as both the inside team of biospherians and key members of Mission Control had training in working with group dynamics. Insights from that experience may help mission planning so that future groups in space cope successfully with inherent group dynamics challenges that arise.

  3. The group approach to AdS space propagators

    International Nuclear Information System (INIS)

    Leonhardt, Thorsten; Manvelyan, Ruben; Ruehl, Werner

    2003-01-01

    We show that AdS two-point functions can be obtained by connecting two points in the interior of AdS space with one point on its boundary by a dual pair of Dobrev's boundary-to-bulk intertwiners and integrating over the boundary point

  4. Spaces on sets

    International Nuclear Information System (INIS)

    Triebel, Hans

    2005-01-01

    This paper deals with spaces B s pq and F s pq of positive smoothness s>0, based on L p -spaces with 0< p≤∞ and reproducing formulae for smooth functions. These spaces are compared with other B-spaces and F-spaces obtained by different means

  5. Chemical modification and pH dependence of kinetic parameters to identify functional groups in a glucosyltransferase from Strep. Mutans

    International Nuclear Information System (INIS)

    Bell, J.E.; Leone, A.; Bell, E.T.

    1986-01-01

    A glucosyltransferase, forming a predominantly al-6 linked glucan, was partially purified from the culture filtrate of S. mutans GS-5. The kinetic properties of the enzyme, assessed using the transfer of 14 C glucose from sucrose into total glucan, were studied at pH values from pH 3.5 to 6.5. From the dependence of km on pH, a group with pKa = 5.5 must be protonated to maximize substrate binding. From plots of V/sub max/ vs pH two groups, with pKa's of 4.5 and 5.5 were indicated. The results suggest the involvement of either two carboxyl groups (one protonated, one unprotonated in the native enzyme) or a carboxyl group (unprotonated) and some other protonated group such as histidine, cysteine. Chemical modification studies showed that Diethylyrocarbonate (histidine specific) had no effect on enzyme activity while modification with p-phydroxy-mercuribenzoate or iodoacetic acid (sulfhydryl reactive) and carbodimide reagents (carboxyl specific) resulted in almost complete inactivation. Activity loss was dependent upon time of incubation and reagent concentration. The disaccharide lylose, (shown to be an inhibitor of the enzyme with similar affinity to sucrose) offers no protection against modification by the sulfhydryl reactive reagents

  6. Lithium amide (LiNH2) under pressure.

    Science.gov (United States)

    Prasad, Dasari L V K; Ashcroft, N W; Hoffmann, Roald

    2012-10-11

    Static high pressure lithium amide (LiNH(2)) crystal structures are predicted using evolutionary structure search methodologies and intuitive approaches. In the process, we explore the relationship of the structure and properties of solid LiNH(2) to its molecular monomer and dimer, as well as its valence-isoelectronic crystalline phases of methane, water, and ammonia all under pressure. A NaNH(2) (Fddd) structure type is found to be competitive for the ground state of LiNH(2) above 6 GPa with the P = 1 atm I4[overline] phase. Three novel phases emerge at 11 (P4[overline]2(1)m), 13 (P4(2)/ncm), and 46 GPa (P2(1)2(1)2(1)), still containing molecular amide anions, which begin to form N-H···N hydrogen bonds. The P2(1)2(1)2(1) phase remains stable over a wide pressure range. This phase and another Pmc2(1) structure found at 280 GPa have infinite ···(H)N···H···N(H)···H polymeric zigzag chains comprising symmetric N···H···N hydrogen bonds with one NH bond kept out of the chain, an interesting general feature found in many of our high pressure (>280 GPa) LiNH(2) structures, with analogies in high pressure H(2)O-ices. All the predicted low enthalpy LiNH(2) phases are calculated to be enthalpically stable with respect to their elements but resist metallization with increasing pressure up to several TPa. The possibility of Li sublattice melting in the intermediate pressure range structures is raised.

  7. p-Forms and diffeomorphisms: Hamiltonian formulation

    Science.gov (United States)

    Baulieu, Laurent; Henneaux, Marc

    1987-07-01

    The BRST charges corresponding to various (equivalent) ways of writing the action of the diffeomorphism group on p-form gauge fields are canonically related by a canonical transformation in the extended phase space which is explicitly constructed. The occurrence of higher order structure functions is pointed out. Also at: Centro de Estudios Cientificos de Santiago, Casilla 16443, Santiago 9, Chile.

  8. Superspace group descriptions of the symmetries of incommensurate urea inclusion compounds

    NARCIS (Netherlands)

    vanSmaalen, S; Harris, KDM

    1996-01-01

    Urea inclusion compounds are a class of incommensurate composite crystals. The urea molecules form a three-dimensionally connected network, with approximate space group symmetry P6(1)22. This network contains tunnels (channels), which accommodate guest molecules. The periodicities of the urea

  9. SiP monolayers: New 2D structures of group IV-V compounds for visible-light photohydrolytic catalysts

    Science.gov (United States)

    Ma, Zhinan; Zhuang, Jibin; Zhang, Xu; Zhou, Zhen

    2018-06-01

    Because of graphene and phosphorene, two-dimensional (2D) layered materials of group IV and group V elements arouse great interest. However, group IV-V monolayers have not received due attention. In this work, three types of SiP monolayers were computationally designed to explore their electronic structure and optical properties. Computations confirm the stability of these monolayers, which are all indirect-bandgap semiconductors with bandgaps in the range 1.38-2.21 eV. The bandgaps straddle the redox potentials of water at pH = 0, indicating the potential of the monolayers for use as watersplitting photocatalysts. The computed optical properties demonstrate that certain monolayers of SiP 2D materials are absorbers of visible light and would serve as good candidates for optoelectronic devices.

  10. S1P lyase in thymic perivascular spaces promotes egress of mature thymocytes via up-regulation of S1P receptor 1.

    Science.gov (United States)

    Maeda, Yasuhiro; Yagi, Hideki; Takemoto, Kana; Utsumi, Hiroyuki; Fukunari, Atsushi; Sugahara, Kunio; Masuko, Takashi; Chiba, Kenji

    2014-05-01

    Sphingosine 1-phosphate (S1P) and S1P receptor 1 (S1P1) play an important role in the egress of mature CD4 or CD8 single-positive (SP) thymocytes from the thymus. Fingolimod hydrochloride (FTY720), an S1P1 functional antagonist, induced significant accumulation of CD62L(high)CD69(low) mature SP thymocytes in the thymic medulla. Immunohistochemical staining using anti-S1P1 antibody revealed that S1P1 is predominantly expressed on thymocytes in the thymic medulla and is strongly down-regulated even at 3h after FTY720 administration. 2-Acetyl-4-tetrahydroxybutylimidazole (THI), an S1P lyase inhibitor, also induced accumulation of mature SP thymocytes in the thymic medulla with an enlargement of the perivascular spaces (PVS). At 6h after THI administration, S1P1-expressing thymocytes reduced partially as if to form clusters and hardly existed in the proximity of CD31-expressing blood vessels in the thymic medulla, suggesting S1P lyase expression in the cells constructing thymic medullary PVS. To determine the cells expressing S1P lyase in the thymus, we newly established a mAb (YK19-2) specific for mouse S1P lyase. Immunohistochemical staining with YK19-2 revealed that S1P lyase is predominantly expressed in non-lymphoid thymic stromal cells in the thymic medulla. In the thymic medullary PVS, S1P lyase was expressed in ER-TR7-positive cells (reticular fibroblasts and pericytes) and CD31-positive vascular endothelial cells. Our findings suggest that S1P lyase expressed in the thymic medullary PVS keeps the tissue S1P concentration low around the vessels and promotes thymic egress via up-regulation of S1P1.

  11. Between-group behaviour in health care: gaps, edges, boundaries, disconnections, weak ties, spaces and holes. A systematic review

    Directory of Open Access Journals (Sweden)

    Braithwaite Jeffrey

    2010-12-01

    Full Text Available Abstract Background Gaps are typically regarded as a problem to be solved. People are stimulated to close or plug them. Researchers are moved to fill deficits in the literature in order to realise a more complete knowledge base, health authorities want to bridge policy-practice disconnections, managers to secure resources to remedy shortfalls between poor and idealised care, and clinicians to provide services to patients across the divides of organisational silos. Despite practical and policy work in many health systems to bridge gaps, it is valuable to study research examining them for the insights provided. Structural holes, spaces between social clusters and weak or absent ties represent fissures in networks, located in less densely populated parts of otherwise closely connected social structures. Such gaps are useful as they illustrate how communication potentially breaks down or interactivity fails. This paper discusses empirical and theoretical work on this phenomenon with the aim of analysing a specific exemplar, the structures of silos within health care organisations. Methods The research literature on social spaces, holes, gaps, boundaries and edges was searched systematically, and separated into health [n = 13] and non-health [n = 55] samples. The health literature was reviewed and synthesised in order to understand the circumstances between stakeholders and stakeholder groups that both provide threats to networked interactions and opportunities to strengthen the fabric of organisational and institutional inter-relationships. Results The research examples illuminate various network structure characteristics and group interactions. They explicate a range of opportunities for improved social and professional relations that understanding structural holes, social spaces and absent ties affords. A principal finding is that these kinds of gaps illustrate the conditions under which connections are strained or have been severed, where the

  12. Quantum isometry groups

    Indian Academy of Sciences (India)

    Jyotishman Bhowmick

    2015-11-07

    Nov 7, 2015 ... Classical. Quantum. Background. Compact Hausdorff space. Unital C∗ algebra. Gelfand-Naimark. Compact Group. Compact Quantum Group. Woronowicz. Group Action. Coaction. Woronowicz. Riemannian manifold. Spectral triple. Connes. Isometry group. Quantum Isometry Group. To be discussed.

  13. The extensions of space-time. Physics in the 8-dimensional homogeneous space D = SU(2,2)/K

    International Nuclear Information System (INIS)

    Barut, A.O.

    1993-07-01

    The Minkowski space-time is only a boundary of a bigger homogeneous space of the conformal group. The conformal group is the symmetry group of our most fundamental massless wave equations. These extended groups and spaces have many remarkable properties and physical implications. (author). 36 refs

  14. On the Elliptic Nonabelian Fourier Transform for Unipotent Representations of p-Adic Groups

    NARCIS (Netherlands)

    Ciubotaru, D.; Opdam, E.; Cogdell, J.; Kim, J.-L.; Zhu, C.-B.

    2017-01-01

    In this paper, we consider the relation between two nonabelian Fourier transforms. The first one is defined in terms of the Langlands-Kazhdan-Lusztig parameters for unipotent elliptic representations of a split p-adic group and the second is defined in terms of the pseudocoefficients of these

  15. Life science experiments performed in space in the ISS/Kibo facility and future research plans.

    Science.gov (United States)

    Ohnishi, Takeo

    2016-08-01

    Over the past several years, current techniques in molecular biology have been used to perform experiments in space, focusing on the nature and effects of space radiation. In the Japanese 'Kibo' facility in the International Space Station (ISS), the Japan Aerospace Exploration Agency (JAXA) has performed five life science experiments since 2009, and two additional experiments are currently in progress. The first life science experiment in space was the 'Rad Gene' project, which utilized two human cultured lymphoblastoid cell lines containing a mutated P53 : gene (m P53 : ) and a parental wild-type P53 : gene (wt P53 : ) respectively. Four parameters were examined: (i) detecting space radiation-induced DSBs by observing γH2AX foci; (ii) observing P53 : -dependent gene expression during space flight; (iii) observing P53 : -dependent gene expression after space flight; and (iv) observing the adaptive response in the two cell lines containing the mutated and wild type P53 : genes after exposure to space radiation. These observations were completed and have been reported, and this paper is a review of these experiments. In addition, recent new information from space-based experiments involving radiation biology is presented here. These experiments involve human cultured cells, silkworm eggs, mouse embryonic stem cells and mouse eggs in various experiments designed by other principal investigators in the ISS/Kibo. The progress of Japanese science groups involved in these space experiments together with JAXA are also discussed here. The Japanese Society for Biological Sciences in Space (JSBSS), the Utilization Committee of Space Environment Science (UCSES) and the Science Council of Japan (ACJ) have supported these new projects and new experimental facilities in ISS/Kibo. Currently, these organizations are proposing new experiments for the ISS through 2024. © The Author 2016. Published by Oxford University Press on behalf of The Japan Radiation Research Society and

  16. Open problems and results in the group theoretic approach to quantum gravity via the BMS group and its generalizations

    International Nuclear Information System (INIS)

    Melas, Evangelos

    2011-01-01

    The Bondi-Metzner-Sachs group B is the common asymptotic group of all asymptotically flat (lorentzian) space-times, and is the best candidate for the universal symmetry group of General Relativity. However, in quantum gravity, complexified or euclidean versions of General Relativity are frequently considered. McCarthy has shown that there are forty-two generalizations of B for these versions of the theory and a variety of further ones, either real in any signature, or complex. A firm foundation for quantum gravity can be laid by following through the analogue of Wigner's programme for special relativity with B replacing the Poincare group P. Here the main results which have been obtained so far in this research programme are reported and the more important open problems are stated.

  17. Symmetry and group theory in chemistry

    CERN Document Server

    Ladd, M

    1998-01-01

    A comprehensive discussion of group theory in the context of molecular and crystal symmetry, this book covers both point-group and space-group symmetries.Provides a comprehensive discussion of group theory in the context of molecular and crystal symmetryCovers both point-group and space-group symmetriesIncludes tutorial solutions

  18. Elementary particles in curved spaces

    International Nuclear Information System (INIS)

    Lazanu, I.

    2004-01-01

    The theories in particle physics are developed currently, in Minkowski space-time starting from the Poincare group. A physical theory in flat space can be seen as the limit of a more general physical theory in a curved space. At the present time, a theory of particles in curved space does not exist, and thus the only possibility is to extend the existent theories in these spaces. A formidable obstacle to the extension of physical models is the absence of groups of motion in more general Riemann spaces. A space of constant curvature has a group of motion that, although differs from that of a flat space, has the same number of parameters and could permit some generalisations. In this contribution we try to investigate some physical implications of the presumable existence of elementary particles in curved space. In de Sitter space (dS) the invariant rest mass is a combination of the Poincare rest mass and the generalised angular momentum of a particle and it permits to establish a correlation with the vacuum energy and with the cosmological constant. The consequences are significant because in an experiment the local structure of space-time departs from the Minkowski space and becomes a dS or AdS space-time. Discrete symmetry characteristics of the dS/AdS group suggest some arguments for the possible existence of the 'mirror matter'. (author)

  19. Geometric modular action and transformation groups

    International Nuclear Information System (INIS)

    Summers, S.J.

    1996-01-01

    We study a weak form of geometric modular action, which is naturally associated with transformation groups of partially ordered sets and which provides these groups with projective representations. Under suitable conditions it is shown that these groups are implemented by point transformations of topological spaces serving as models for space-times, leading to groups which may be interpreted as symmetry groups of the space-times. As concrete examples, it is shown that the Poincare group and the de Sitter group can be derived from this condition of geometric modular action. Further consequences and examples are discussed. (orig.)

  20. Fisher's Zeros as the Boundary of Renormalization Group Flows in Complex Coupling Spaces

    International Nuclear Information System (INIS)

    Denbleyker, A.; Du Daping; Liu Yuzhi; Meurice, Y.; Zou Haiyuan

    2010-01-01

    We propose new methods to extend the renormalization group transformation to complex coupling spaces. We argue that Fisher's zeros are located at the boundary of the complex basin of attraction of infrared fixed points. We support this picture with numerical calculations at finite volume for two-dimensional O(N) models in the large-N limit and the hierarchical Ising model. We present numerical evidence that, as the volume increases, the Fisher's zeros of four-dimensional pure gauge SU(2) lattice gauge theory with a Wilson action stabilize at a distance larger than 0.15 from the real axis in the complex β=4/g 2 plane. We discuss the implications for proofs of confinement and searches for nontrivial infrared fixed points in models beyond the standard model.

  1. Un caso de grupo sanguíneo raro: fenotipo p A rare blood group: p phenotype

    Directory of Open Access Journals (Sweden)

    Carlos D. De La Vega Elena

    2009-12-01

    Full Text Available Un individuo con un fenotipo eritrocitario raro carece de uno o varios antígenos presentes en la mayor parte de la población de pertenencia. Cuando presenta el anticuerpo correspondiente, se pueden producir complicaciones perinatales, transfusionales y/o transplantológicas. Se presenta el caso de una embarazada aloinmunizada derivada a nuestro servicio en la semana 12 de su tercera gesta para su evaluación y seguimiento. El diagnóstico inmunohematológico le asignó el excepcional fenotipo "p" (aproximadamente 1/200 000 individuos, asociado con una mayor tasa de abortos espontáneos y a reacciones transfusionales graves cuando se transfunden unidades incompatibles. El estudio del gen A4GALT demostró la presencia de la mutación c.752C > T en doble dosis. Esta mutación lleva a un cambio de una prolina por una leucina en el residuo 251 de la 4-α-galactosiltransferasa. Por parto inducido por sufrimiento fetal, nace a las 36 semanas una bebé con prueba de antiglobulina (Coombs directa negativa, eluido reactivo, con ictericia que requirió luminoterapia. Una semana después el neonato fue externado sin secuelas aparentes. Posteriormente, a raíz de una cirugía inminente y la improbabilidad de encontrar sangre compatible, se elaboró un plan para cubrir las posibles demandas. Este caso pone en evidencia la necesidad de contar a nivel nacional con un laboratorio de referencia de inmunohematología y un banco de sangre de grupos raros, que permita resolver con celeridad situaciones que requieran transfundir a estos individuos.A rare blood group is usually defined as the absence of a high prevalence antigen or the absence of several antigens within a single blood group system. These individuals may develop clinically significant red cell antibodies to the high incidence red cell antigens they lack. A 33-year-old alloimmunized woman was referred to our center at the 12th week of her third pregnancy for evaluation and follow up. The laboratory

  2. Investigation of Some Potent Medicinal Plants of N.E.INDIA with Respect to Thermophysical, Chromatographic and Crystallographic Properties

    Science.gov (United States)

    Bora, M. N.; Kalita, Mahendra

    2010-06-01

    North East India is readily available of various kinds of medicinal plants. A lot of studies on thermophysical properties of plant leaves, fluids, stems and roots had already been made[3,4,8]. In the present studies of thermophysical properties, chromatographic and crystallographic properties of specific medicinal plant leaves (Azadirechta indica)A, (Vinca rosea)B, (Clerodrendrum colebrookianum)C, (Osimum sanctum)D and fruits (Chisocheton paniculatus) E, and (Cudrania javanensis) F have been made plant based drugs for curing for different chronic diseases. The thermophysical properties of these leaves and fruits have been studies with XRD, XRF, TG, DTG, DTA, and DSC thermograms. From weight loss(%), time and temperature variations, the Activation Energies of these medicinal plant samples have been computed. The thermal stability is found more for the fruits samples than that of the leave samples. Thermal behaviours of all six samples have shown hygroscopic behaviour. The results TG, DTG and DTA thermograms confirmed that all samples show similar dehydration and decomposition reactions and hydrophilic nature. Both chromatographic techniques thin layer (TLC) and Column chromatography have been used for separation of components of the mixtures of samples. From these methods of the fruit sample E a pure crystalline white solids have been identified and confirm them as (MK 01) α-isomer. Our interest to study the molecular and crystal structure of the sample E. The single crystal of (MK 01) is found to be orthorhombic cell with lattice parameters a = 10ṡ699(3)Å b = 15ṡ5100(4)Å c = 16ṡ626(4)Å α = 90° β = 90° γ = 90° with space group P212121 Again from fruit sample F a light yellow solid is isolated and on crystallization give crystalline solid MN-01 and MN-02 and it is confirmed that these two compounds are unsaturated isoflavonoids. The single crystal of MN-01 has been found monoclinic with lattice parameters a = 6.2374(11)Å, b = 8.4243(11)Å, c = 21

  3. Co-H-spaces and almost localization

    OpenAIRE

    Costoya, Cristina; Iwase, Norio

    2012-01-01

    Apart from simply-connected spaces, a non simply-connected co-H-space is a typical example of a space X with a co-action of $B\\pi_1(X)$ along $r^X : X \\rightarrow B\\pi_{1}(X)$ the classifying map of the universal covering. If such a space X is actually a co-H-space, then the fibrewise p-localization of $r^X$ (or the `almost' p-localization of X) is a fibrewise co-H-space (or an `almost' co-H-space, resp.) for every prime p. In this paper, we show that the converse statement is true, i.e., for...

  4. A Comparative Study of Deep Neck Abscess with Regards to Anatomical Location and Age Groups Using CT and Clinical Data

    International Nuclear Information System (INIS)

    Park, Chan Ho; Han, Jong Kyu; Kim, Young Tong; Shin, Hyeong Cheol; Kim, Hyung Hwan; Jou, Sung Shick

    2012-01-01

    To evaluate differences anatomical location and age groups on CT and clinical data in deep neck abscess. This study included 200 patients who underwent CT and were diagnosed with a deep neck abscess, from December 2005 to July 2010. Patients were divided into four groups by age (children, adolescent, adult, elderly). Next, the anatomic location, location multiplicity and clinical data regarding the deep neck abscesses were analyzed retrospectively. The deep neck abscesses observed were defined as superficial or deep and partitioned into sub-groups, with further analysis of their clinical data. The incidence of the parapharyngeal abscess was more frequent in children and elderly groups (p < 0.05). The masticator abscess was only observed among patients in the elderly group (p < 0.05). Multiple locations were observed with increased frequency in children and elderly groups (p < 0.05). Swelling in the neck was more frequently observed in children and elderly groups (p < 0.05), cervical lymphadenitis was frequently seen in children and adolescent groups (p < 0.05), and the incidence of symptoms including sore throat were significantly increased in adolescent and adult groups (p < 0.05). Location multiplicity was significantly higher in parapharyngeal, retropharyngeal, submandibular, danger, visceral and masticator spaces than other spaces (p < 0.05). With regards to anatomic location, neck swelling was more frequent in superficial group and sore throat was more frequent in deep group (p < 0.05). Deep neck abscess would show significant differences with regards to the abscess location, location multiplicity, and clinical symptoms according to age. The clinical symptoms observed are dependent on the anatomic location as defined by a superficial or deep abscess.

  5. Joint Space Narrowing in Patients With Pisotriquetral Osteoarthritis.

    Science.gov (United States)

    Ten Berg, Paul W L; Heeg, Erik; Strackee, Simon D; Streekstra, Geert J

    2017-09-01

    Patients with suspected pisotriquetral osteoarthritis may show joint space narrowing. However, the extent of joint space narrowing and its deviation from the joint space width (JSW) in normal anatomy is unknown. In this pathoanatomic study, we therefore compared the JSW in the pisotriquetral joint between osteoarthritic patient wrists and healthy wrists. We reviewed preoperative computed tomography (CT) scans of 8 wrists of patients with ulnar-sided wrist pain who underwent a pisiformectomy with confirmed pisotriquetral osteoarthritis at surgery. We also reviewed CT scans of 20 normal wrists from healthy volunteers serving as control group. Three-dimensional CT models of the pisiform and triquetrum were obtained from both affected and normal wrists, after which the minimum JSW was calculated in an automated fashion. In the patient group, the median (interquartile range) of the minimum JSW was 0.1 mm (0.0-0.2), and in the control group, 0.8 mm (0.3-0.9) ( P = .007). We showed that the pisotriquetral joint space in osteoarthritic patient wrists was significantly narrowed compared with healthy wrists. These results suggest that JSW evaluation has a potential diagnostic value in the work-up of patients with suspected pisotriquetral osteoarthritis. This is an interesting area for future clinical research, especially because no gold standard for diagnosing pisotriquetral osteoarthritis has been established yet.

  6. The effectiveness of a Group Triple P with Chinese parents who have a child with developmental disabilities: a randomized controlled trial.

    Science.gov (United States)

    Leung, Cynthia; Fan, Angel; Sanders, Matthew R

    2013-03-01

    The study examined the effectiveness of Group Triple P, a Level 4 variant of the Triple P multilevel system of parenting support, with Chinese parents who had a preschool aged child with a developmental disability, using randomized controlled trial design. Participants (Intervention group: 42; Waitlist Control group: 39) completed measures on child behaviour, parental stress, dysfunctional discipline styles and parental conflict before and after program completion by the Intervention group. Intervention group participants also completed these same measures six months after program completion. Compared to the Waitlist Control group, parents receiving Group Triple P reported significantly lower levels of child behaviour problems, parental stress, dysfunctional discipline style and parental conflict scores. The Intervention group participants maintained their gains six months after program completion. The results provided promising evidence for the Level 4 Group Triple P as an effective intervention program for Chinese parents who have preschool aged children with developmental disabilities. Copyright © 2012 Elsevier Ltd. All rights reserved.

  7. Effects of incentives on psychosocial performances in simulated space-dwelling groups

    Science.gov (United States)

    Hienz, Robert D.; Brady, Joseph V.; Hursh, Steven R.; Gasior, Eric D.; Spence, Kevin R.; Emurian, Henry H.

    Prior research with individually isolated 3-person crews in a distributed, interactive, planetary exploration simulation examined the effects of communication constraints and crew configuration changes on crew performance and psychosocial self-report measures. The present report extends these findings to a model of performance maintenance that operationalizes conditions under which disruptive affective responses by crew participants might be anticipated to emerge. Experiments evaluated the effects of changes in incentive conditions on crew performance and self-report measures in simulated space-dwelling groups. Crews participated in a simulated planetary exploration mission that required identification, collection, and analysis of geologic samples. Results showed that crew performance effectiveness was unaffected by either positive or negative incentive conditions, while self-report measures were differentially affected—negative incentive conditions produced pronounced increases in negative self-report ratings and decreases in positive self-report ratings, while positive incentive conditions produced increased positive self-report ratings only. Thus, incentive conditions associated with simulated spaceflight missions can significantly affect psychosocial adaptation without compromising task performance effectiveness in trained and experienced crews.

  8. Space research in the Netherlands 1980

    International Nuclear Information System (INIS)

    1981-01-01

    In 1960, the Royal Netherlands Academy of Arts and Sciences established a committee with the task of coordinating space research in the Netherlands and maintaining the necessary international contacts. This committe, usually called GROC, has instituted four working groups, in which most of the Netherlands space research is concentrated. These groups are: Working Group for Solar and Stellar Space Research, Working Group for Cosmic Rays, Working Group for Photometry and the Working Group for Satellite Geodesy. General information on space research in the Netherlands Anno 1980 is given. Detailed data about the working groups, their work during 1980 and their programmes are presented, together with a survey of their scientific publications. A financial summary is also included. (Auth.)

  9. Y spaces and global smooth solution of fractional Navier-Stokes equations with initial value in the critical oscillation spaces

    Science.gov (United States)

    Yang, Qixiang; Yang, Haibo

    2018-04-01

    For fractional Navier-Stokes equations and critical initial spaces X, one used to establish the well-posedness in the solution space which is contained in C (R+ , X). In this paper, for heat flow, we apply parameter Meyer wavelets to introduce Y spaces Y m , β where Y m , β is not contained in C (R+, B˙∞ 1 - 2 β , ∞). Consequently, for 1/2 global well-posedness of fractional Navier-Stokes equations with small initial data in all the critical oscillation spaces. The critical oscillation spaces may be any Besov-Morrey spaces (B˙p,q γ1 ,γ2 (Rn)) n or any Triebel-Lizorkin-Morrey spaces (F˙p,q γ1 ,γ2 (Rn)) n where 1 ≤ p , q ≤ ∞ , 0 ≤γ2 ≤ n/p, γ1 -γ2 = 1 - 2 β. These critical spaces include many known spaces. For example, Besov spaces, Sobolev spaces, Bloch spaces, Q-spaces, Morrey spaces and Triebel-Lizorkin spaces etc.

  10. A generalization of the spaces lp

    International Nuclear Information System (INIS)

    Lubuma, M.S.

    1989-05-01

    The classical spaces l p =l p (N,R) are generalized into topological vector spaces l 0 (I,Y) by replacing N and R by a non empty set I and a topological vector space Y respectively. Various topological and order structures are considered by showing that l p (I,Y) satisfies a given property if Y does so. For normed spaces, a characterization of the reflexivity and of the dual of l p (I,Y) is given. (author). 10 refs

  11. Axial p-n junction and space charge limited current in single GaN nanowire

    Science.gov (United States)

    Fang, Zhihua; Donatini, Fabrice; Daudin, Bruno; Pernot, Julien

    2018-01-01

    The electrical characterizations of individual basic GaN nanostructures, such as axial nanowire (NW) p-n junctions, are becoming indispensable and crucial for the fully controlled realization of GaN NW based devices. In this study, electron beam induced current (EBIC) measurements were performed on two single axial GaN p-n junction NWs grown by plasma-assisted molecular beam epitaxy. I-V characteristics revealed that both ohmic and space charge limited current (SCLC) regimes occur in GaN p-n junction NW. Thanks to an improved contact process, both the electric field induced by the p-n junction and the SCLC in the p-part of GaN NW were disclosed and delineated by EBIC signals under different biases. Analyzing the EBIC profiles in the vicinity of the p-n junction under 0 V and reverse bias, we deduced a depletion width in the range of 116-125 nm. Following our previous work, the acceptor N a doping level was estimated to be 2-3 × 1017 at cm-3 assuming a donor level N d of 2-3 × 1018 at cm-3. The hole diffusion length in n-GaN was determined to be 75 nm for NW #1 and 43 nm for NW #2, demonstrating a low surface recombination velocity at the m-plane facet of n-GaN NW. Under forward bias, EBIC imaging visualized the electric field induced by the SCLC close to p-side contact, in agreement with unusual SCLC previously reported in GaN NWs.

  12. Axial p-n junction and space charge limited current in single GaN nanowire.

    Science.gov (United States)

    Fang, Zhihua; Donatini, Fabrice; Daudin, Bruno; Pernot, Julien

    2018-01-05

    The electrical characterizations of individual basic GaN nanostructures, such as axial nanowire (NW) p-n junctions, are becoming indispensable and crucial for the fully controlled realization of GaN NW based devices. In this study, electron beam induced current (EBIC) measurements were performed on two single axial GaN p-n junction NWs grown by plasma-assisted molecular beam epitaxy. I-V characteristics revealed that both ohmic and space charge limited current (SCLC) regimes occur in GaN p-n junction NW. Thanks to an improved contact process, both the electric field induced by the p-n junction and the SCLC in the p-part of GaN NW were disclosed and delineated by EBIC signals under different biases. Analyzing the EBIC profiles in the vicinity of the p-n junction under 0 V and reverse bias, we deduced a depletion width in the range of 116-125 nm. Following our previous work, the acceptor N a doping level was estimated to be 2-3 × 10 17 at cm -3 assuming a donor level N d of 2-3 × 10 18 at cm -3 . The hole diffusion length in n-GaN was determined to be 75 nm for NW #1 and 43 nm for NW #2, demonstrating a low surface recombination velocity at the m-plane facet of n-GaN NW. Under forward bias, EBIC imaging visualized the electric field induced by the SCLC close to p-side contact, in agreement with unusual SCLC previously reported in GaN NWs.

  13. The Poincare group as the symmetry group of canonical general relativity

    International Nuclear Information System (INIS)

    Beig, R.; Murchadha, N. o

    1986-01-01

    This work reconsiders the formulation, due to Regge and Teitelboim, of the phase space approach to General Relativity in the asymptotically flat context, phrasing it in the language of symplectic geometry. The necessary boundary conditions at spatial infinity are spelled out in detail. Precise meaning is given to the statement that, as a result of these boundary conditions, the Poincare group acts as a symmetry group on the phase space of G.R. This situation is compared with the spi-picture of Ashtekar and Hansen, where a larger asymptotic symmetry group is obtained. (Author)

  14. $L^{p}$-square function estimates on spaces of homogeneous type and on uniformly rectifiable sets

    CERN Document Server

    Hofmann, Steve; Mitrea, Marius; Morris, Andrew J

    2017-01-01

    The authors establish square function estimates for integral operators on uniformly rectifiable sets by proving a local T(b) theorem and applying it to show that such estimates are stable under the so-called big pieces functor. More generally, they consider integral operators associated with Ahlfors-David regular sets of arbitrary codimension in ambient quasi-metric spaces. The local T(b) theorem is then used to establish an inductive scheme in which square function estimates on so-called big pieces of an Ahlfors-David regular set are proved to be sufficient for square function estimates to hold on the entire set. Extrapolation results for L^p and Hardy space versions of these estimates are also established. Moreover, the authors prove square function estimates for integral operators associated with variable coefficient kernels, including the Schwartz kernels of pseudodifferential operators acting between vector bundles on subdomains with uniformly rectifiable boundaries on manifolds.

  15. EFFECT OF FLOOR SPACE ON SERUM CORTISOL LEVEL OF OSMANABADI KIDS IN MUMBAI REGION OF INDIA

    Directory of Open Access Journals (Sweden)

    Rameswar Panda

    2016-12-01

    Full Text Available This experiment was conducted to find out the effect of different floor space allowance on serum cortisol level of Osmanabadi kids. For this study, eighteen Osmanabadi kids between the age group of 3-4 months were randomly selected irrespective of sex. The selected kids were divided and kept into three different groups with different floor space comprising of 6 kids in each group. GroupT0 (0.8m2 floor space/kid, Group T1 (0.7m2 /kid and Group T2 (0.6m2 /kid. The feeding and other management practices for all the three groups were similar. The blood sample was collected from each goat in fifteen days interval and the serum cortisol concentration (nM/l was determined with the help of Radio Immuno Assay (RIA kit. The average serum cortisol concentration were 12.66 ± 3.08, 10.85 ± 3.51 and 15.18 ± 3.88 nM/l in Group T0, T1 and T2 kids respectively. There was no significant effect (P<0.05 of floor space on cortisol concentration as a stress indicator in Osmanabadi kids.

  16. SpaceTech—Postgraduate space education

    Science.gov (United States)

    de Bruijn, Ferdi J.; Ashford, Edward W.; Larson, Wiley J.

    2008-07-01

    , Interpersonal Skills, Telecommunications, Earth Observation and Navigation. A group CCP, a major asset of this unique program, is a focused project, aimed at the formation of a credible virtual commercial space-related business. Participants exercise space systems engineering fundamentals as well as marketing and business engineering tools, with the goal of creating a financially viable business opportunity. They then present the result, in the form of an unsolicited proposal to potential investors, as well as a varied group of engineers, managers and executives from the space community. During the CCP, participants learn the ties between mission and system design and the potential return to investors. They develop an instinct for the technical concepts and which of the parameters to adjust to make their newly conceived business more effective and profitable.

  17. Creating space for citizenship: The impact of group structure on validating the voices of people with dementia.

    Science.gov (United States)

    Wiersma, Elaine C; O'Connor, Deborah L; Loiselle, Lisa; Hickman, Kathy; Heibein, Bill; Hounam, Brenda; Mann, Jim

    2016-05-01

    Recently, there has been increasing attention given to finding ways to help people diagnosed with dementia 'live well' with their condition. Frequently however, the attention has been placed on the family care partner as the foundation for creating a context that supports the person with dementia to live well. A recent participatory action research (PAR) study highlighted the importance of beginning to challenge some of the assumptions around how best to include family, especially within a context of supporting citizenship. Three advisory groups consisting of 20 people with dementia, 13 care partners, and three service providers, were set up in three locations across Canada to help develop a self-management program for people with dementia. The hubs met monthly for up to two years. One of the topics that emerged as extremely important to consider in the structuring of the program revolved around whether or not these groups should be segregated to include only people with dementia. A thematic analysis of these ongoing discussions coalesced around four inter-related themes: creating safe spaces; maintaining voice and being heard; managing the balancing act; and the importance of solidarity Underpinning these discussions was the fifth theme, recognition that 'one size doesn't fit all'. Overall an important finding was that the presence of family care-partners could have unintended consequences in relation to creating the space for active citizenship to occur in small groups of people with dementia although it could also offer some opportunities. The involvement of care partners in groups with people with dementia is clearly one that is complex without an obvious answer and dependent on a variety of factors to inform a solution, which can and should be questioned and revisited. © The Author(s) 2016.

  18. HUBBLE SPACE TELESCOPE OBSERVATIONS OF ACTIVE ASTEROID 324P/La SAGRA

    Energy Technology Data Exchange (ETDEWEB)

    Jewitt, David; Li, Jing [Department of Earth, Planetary and Space Sciences, UCLA, 595 Charles Young Drive East, Los Angeles, CA 90095-1567 (United States); Agarwal, Jessica [Max Planck Institute for Solar System Research, Justus-von-Liebig-Weg 3, D-37077 Göttingen (Germany); Weaver, Harold [The Johns Hopkins University Applied Physics Laboratory, 11100 Johns Hopkins Road, Laurel, Maryland 20723 (United States); Mutchler, Max [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Larson, Stephen, E-mail: jewitt@ucla.edu [Lunar and Planetary Laboratory, University of Arizona, 1629 E. University Boulevard, Tucson, AZ 85721-0092 (United States)

    2016-09-01

    Hubble Space Telescope observations of active asteroid 324P/La Sagra near perihelion show continued mass loss consistent with the sublimation of near-surface ice. Isophotes of the coma measured from a vantage point below the orbital plane are best matched by steady emission of particles having a nominal size  of  a  ∼ 100 μ m. The inferred rate of mass loss, dM{sub d} / dt  ∼ 0.2 kg s{sup −1}, can be supplied by sublimation of water ice in thermal equilibrium with sunlight from an area as small as 930 m{sup 2}, corresponding to about 0.2% of the nucleus surface. Observations taken from a vantage point only 0.°6 from the orbital plane of 324P set a limit to the velocity of ejection of dust in the direction perpendicular to the plane, V {sub ⊥} < 1 m s{sup −1}. Short-term photometric variations of the near-nucleus region, if related to rotation of the underlying nucleus, rule-out periods ≤3.8 hr and suggest that rotation probably does not play a central role in driving the observed mass loss. We estimate that, in the previous orbit, 324P lost about 4 × 10{sup 7} kg in dust particles, corresponding to 6 × 10{sup −5} of the mass of a 550 m spherical nucleus of assumed density ρ  = 1000 kg m{sup −3}. If continued, mass loss at this rate would limit the lifetime of 324P to ∼1.6 × 10{sup 4} orbits (about 10{sup 5} years). To survive for the 100–400 Myr timescales corresponding to dynamical and collisional stability requires a duty cycle of 2 × 10{sup −4} ≤  f{sub d}  ≤ 8 × 10{sup −4}. Unless its time in orbit is overestimated by many orders of magnitude, 324P is revealed as a briefly active member of a vast population of otherwise dormant ice-containing asteroids.

  19. Crystallization and preliminary X-ray crystallographic analysis of Thermotoga maritima CheA P3-P4-P5 domains in complex with CheW

    International Nuclear Information System (INIS)

    Park, SangYoun; Kim, Keon Young; Kim, Sunmin; Crane, Brian R.

    2012-01-01

    T. maritima CheA P3-P4-P5 domains were crystallized in complex with CheW. Low-resolution diffraction data were collected to ∼8 Å using synchrotron X-ray radiation. The CheA–CheW complex plays a key role in bacterial chemotaxis signal transduction by initiating phosphotransfer to response regulators via coupling to the chemoreceptors. CheA (P3-P4-P5 domains) and CheW from Thermotoga maritima were overexpressed in Escherichia coli and crystallized as a complex at 298 K using ammonium dihydrogen phosphate as a precipitant. X-ray diffraction data were collected to ∼8 Å resolution at 100 K using synchrotron radiation. The crystal belonged to space group I222 or I2 1 2 1 2 1 , with unit-cell parameters a = 184.2, b = 286.4, c = 327.7 Å. The asymmetric unit may contain six to ten CheA–CheW molecules

  20. Efimov spaces and the separable quotient problem for spaces C-P(K)

    Czech Academy of Sciences Publication Activity Database

    Kąkol, Jerzy; Śliwa, W.

    2018-01-01

    Roč. 457, č. 1 (2018), s. 104-113 ISSN 0022-247X R&D Projects: GA ČR GF16-34860L Institutional support: RVO:67985840 Keywords : spaces of continuous functions * pointwise topology * separable quotient problem Subject RIV: BA - General Mathematics OBOR OECD: Pure mathematics Impact factor: 1.064, year: 2016 http://www. science direct.com/ science /article/pii/S0022247X17307588?via%3Dihub

  1. Efimov spaces and the separable quotient problem for spaces C-P(K)

    Czech Academy of Sciences Publication Activity Database

    Kąkol, Jerzy; Śliwa, W.

    2018-01-01

    Roč. 457, č. 1 (2018), s. 104-113 ISSN 0022-247X R&D Projects: GA ČR GF16-34860L Institutional support: RVO:67985840 Keywords : spaces of continuous functions * pointwise topology * separable quotient problem Subject RIV: BA - General Mathematics OBOR OECD: Pure mathematics Impact factor: 1.064, year: 2016 http://www.sciencedirect.com/science/article/pii/S0022247X17307588?via%3Dihub

  2. On spaces of functions of smoothness zero

    International Nuclear Information System (INIS)

    Besov, Oleg V

    2012-01-01

    The paper is concerned with the new spaces B-bar p,q 0 of functions of smoothness zero defined on the n-dimensional Euclidean space R n or on a subdomain G of R n . These spaces are compared with the spaces B p,q 0 (R n ) and bmo(R n ). The embedding theorems for Sobolev spaces are refined in terms of the space B-bar p,q 0 with the limiting exponent. Bibliography: 8 titles.

  3. Factorizable sheaves and quantum groups

    CERN Document Server

    Bezrukavnikov, Roman; Schechtman, Vadim

    1998-01-01

    The book is devoted to the geometrical construction of the representations of Lusztig's small quantum groups at roots of unity. These representations are realized as some spaces of vanishing cycles of perverse sheaves over configuration spaces. As an application, the bundles of conformal blocks over the moduli spaces of curves are studied. The book is intended for specialists in group representations and algebraic geometry.

  4. Novel association of soluble intercellular adhesion molecule 1 and soluble P-selectin with the ABO blood group in a Chinese population.

    Science.gov (United States)

    Zhang, Wenjing; Xu, Qun; Zhuang, Yunlong; Chen, Yuanfeng

    2016-08-01

    Recent studies have reported that the ABO gene can affect circulating expression levels of soluble intercellular adhesion molecule 1 (sICAM-1) and soluble P-selectin (sP-selectin) in Caucasians. However, several factors may affect the association, including the distribution and variations of the ABO gene, ethnic diversity and the inflammatory response status. The aim of the present study was to investigate this issue in Asian subjects of various blood groups. A total of 800 blood samples were randomly selected from healthy blood donors. The ABO blood groups were examined using standard serological tests, and ABO genotypes of group A and group AB specimens were analyzed. Plasma concentrations of sICAM-1 and sP-selectin were detected by standard enzyme-linked immunosorbent assays. In healthy Chinese individuals, blood group A was detected to be significantly associated with lower circulating expression levels of sICAM-1 and sP-selectin, compared with group O. Individuals with ≥1 A1 allele had significantly lower expression levels of sICAM-1 and sP-selectin compared with all other ABO groups. The data indicate the significant association of ABO blood group antigens with sICAM-1 and sP-selectin expression levels in a healthy Chinese population, independent of the specific variations and distributions of ABO blood groups among ethnic populations. This result provides evidence for the previously unidentified role of ABO blood group antigens in the regulation of the inflammatory adhesion process. Accordingly, it can be proposed that ABO blood groups may require consideration when soluble adhesion molecules are identified as predictors for cardiovascular disease.

  5. Practical routes to (SiH₃)₃P: applications in group IV semiconductor activation and in group III-V molecular synthesis.

    Science.gov (United States)

    Tice, Jesse B; Chizmeshya, A V G; Tolle, J; D' Costa, V R; Menendez, J; Kouvetakis, J

    2010-05-21

    The (SiH₃)₃P hydride is introduced as a practical source for n-doping of group IV semiconductors and as a highly-reactive delivery agent of -(SiH₃)₂P functionalities in exploratory synthesis. In contrast to earlier methods, the compound is produced here in high purity quantitative yields via a new single-step method based on reactions of SiH₃Br and (Me₃Sn)₃P, circumventing the need for toxic and unstable starting materials. As an initial demonstration of its utility we synthesized monosubstituted Me₂M-P(SiH₃)₂ (M = Al, Ga, In) derivatives of Me₃M containing the (SiH₃)₂P ligand for the first time, in analogy to the known Me₂M-P(SiMe₃)₂ counterparts. A dimeric structure of Me₂M-P(SiH₃)₂ is proposed on the basis of spectroscopic characterizations and quantum chemical simulations. Next, in the context of materials synthesis, the (SiH₃)₃P compound was used to dope germanium for the first time by building a prototype p(++)Si(100)/i-Ge/n-Ge photodiode structure. The resultant n-type Ge layers contained active carrier concentrations of 3-4 × 10¹⁹ atoms cm⁻³ as determined by spectroscopic ellipsometry and confirmed by SIMS. Strain analysis using high resolution XRD yielded a Si content of 4 × 10²⁰ atoms cm⁻³ in agreement with SIMS and within the range expected for incorporating Si₃P type units into the diamond cubic Ge matrix. Extensive characterizations for structure, morphology and crystallinity indicate that the Si co-dopant plays essentially a passive role and does not compromise the device quality of the host material nor does it fundamentally alter its optical properties.

  6. The premature loss of primary first molars: space loss to molar occlusal relationships and facial patterns.

    Science.gov (United States)

    Alexander, Stanley A; Askari, Marjan; Lewis, Patricia

    2015-03-01

    To investigate space changes with the premature loss of primary first molars and their relationship to permanent molar occlusion and facial forms. Two hundred twenty-six participants (ranging in age from 7 years 8 months to 8 years 2 months; 135 female, 91 male) met all inclusion criteria designed to study space loss as a result of the premature loss of the primary first molar. After 9 months, space loss was evaluated in relationship to molar occlusion and facial form. Statistical evaluation was performed with the paired t-test and with a two-way analysis of variance for independent groups. Patients with leptoprosopic facial form and end-on molar occlusions all exhibited a statistically significant difference when compared to controls in terms of space loss (P molar occlusion displayed space loss as well (P molar occlusion displayed space loss in the maxilla (P molar occlusions showed no significant difference in space loss. The relationship between the first permanent molar occlusion and facial form of the child has an influence on the loss of space at the primary first molar site.

  7. Automorphisms of free groups with boundaries

    DEFF Research Database (Denmark)

    A. Jensen, Craig; Wahl, Nathalie

    2004-01-01

    The automorphisms of free groups with boundaries form a family of groups A_{n,k} closely related to mapping class groups, with the standard automorphisms of free groups as A_{n,0} and (essentially) the symmetric automorphisms of free groups as A_{0,k}. We construct a contractible space L_{n,k} on......The automorphisms of free groups with boundaries form a family of groups A_{n,k} closely related to mapping class groups, with the standard automorphisms of free groups as A_{n,0} and (essentially) the symmetric automorphisms of free groups as A_{0,k}. We construct a contractible space L......_{n,k} on which A_{n,k} acts with finite stabilizers and finite quotient space and deduce a range for the virtual cohomological dimension of A_{n,k}. We also give a presentation of the groups and calculate their first homology group....

  8. Scattering in quantum field theory: the M.P.S.A. approach in complex momentum space

    International Nuclear Information System (INIS)

    Bros, J.

    1981-02-01

    In this course, we intend to show how 'Many-Particle Structure Analysis' (M.P.S.A.) can be worked out in the standard field-theoretical framework, by using integral relations in complex momentum space involving 'l-particle irreducible kernels'. The ultimate purpose of this approach is to obtain the best possible knowledge of the singularities (location, nature, type of ramification) and of the ambient holomorphy (or meromorphy) domains of the n-point Green functions and scattering amplitudes, and at the same time to derive analytic structural equations for them which display the global organization of these singularities. The generation of Landau singularities for integrals and Fredholm resolvents, taken on cycles in complex space, will be explained on the basis of the Picard-Lefschetz formula (presented and used in simple situations). Among various results described, we present and analyse a structural equation for the six-point function (and for the 3 → 3 particle scattering function), valid in a domain containing the three-particle normal threshold

  9. Quantum symmetries of classical spaces

    OpenAIRE

    Bhowmick, Jyotishman; Goswami, Debashish; Roy, Subrata Shyam

    2009-01-01

    We give a general scheme for constructing faithful actions of genuine (noncommutative as $C^*$ algebra) compact quantum groups on classical topological spaces. Using this, we show that: (i) a compact connected classical space can have a faithful action by a genuine compact quantum group, and (ii) there exists a spectral triple on a classical connected compact space for which the quantum group of orientation and volume preserving isometries (in the sense of \\cite{qorient}) is a genuine quantum...

  10. Life science experiments performed in space in the ISS/Kibo facility and future research plans

    International Nuclear Information System (INIS)

    Ohnishi, Takeo

    2016-01-01

    Over the past several years, current techniques in molecular biology have been used to perform experiments in space, focusing on the nature and effects of space radiation. In the Japanese ‘Kibo’ facility in the International Space Station (ISS), the Japan Aerospace Exploration Agency (JAXA) has performed five life science experiments since 2009, and two additional experiments are currently in progress. The first life science experiment in space was the ‘Rad Gene’ project, which utilized two human cultured lymphoblastoid cell lines containing a mutated p53 gene (mp53) and a parental wild-type p53 gene (wtp53) respectively. Four parameters were examined: (i) detecting space radiation–induced DSBs by observing γH2AX foci; (ii) observing p53-dependent gene expression during space flight; (iii) observing p53-dependent gene expression after space flight; and (iv) observing the adaptive response in the two cell lines containing the mutated and wild type p53 genes after exposure to space radiation. These observations were completed and have been reported, and this paper is a review of these experiments. In addition, recent new information from space-based experiments involving radiation biology is presented here. These experiments involve human cultured cells, silkworm eggs, mouse embryonic stem cells and mouse eggs in various experiments designed by other principal investigators in the ISS/Kibo. The progress of Japanese science groups involved in these space experiments together with JAXA are also discussed here. The Japanese Society for Biological Sciences in Space (JSBSS), the Utilization Committee of Space Environment Science (UCSES) and the Science Council of Japan (ACJ) have supported these new projects and new experimental facilities in ISS/Kibo. Currently, these organizations are proposing new experiments for the ISS through 2024

  11. Crystallization and preliminary crystallographic analysis of Abp, a GH27 β-L-arabinopyranosidase from Geobacillus stearothermophilus.

    Science.gov (United States)

    Lansky, Shifra; Salama, Rachel; Solomon, Vered H; Belrhali, Hassan; Shoham, Yuval; Shoham, Gil

    2013-06-01

    Geobacillus stearothermophilus T-6 is a thermophilic soil bacterium that possesses an extensive system for the utilization of hemicellulose. The bacterium produces a small number of endo-acting extracellular enzymes that cleave high-molecular-weight hemicellulolytic polymers into short decorated oligosaccharides, which are further hydrolysed into the respective sugar monomers by a battery of intracellular glycoside hydrolases. One of these intracellular processing enzymes is β-L-arabinopyranosidase (Abp), which is capable of removing β-L-arabinopyranose residues from naturally occurring arabino-polysaccharides. As arabino-polymers constitute a significant part of the hemicellulolytic content of plant biomass, their efficient enzymatic degradation presents an important challenge for many potential biotechnological applications. This aspect has led to an increasing interest in the biochemical characterization and structural analysis of this and related hemicellulases. Abp from G. stearothermophilus T-6 has recently been cloned, overexpressed, purified, biochemically characterized and crystallized in our laboratory, as part of its complete structure-function study. The best crystals obtained for this enzyme belonged to the primitive orthorhombic space group P2(1)2(1)2(1), with average unit-cell parameters a = 107.7, b = 202.2, c = 287.3 Å. Full diffraction data sets to 2.3 Å resolution have been collected for both the wild-type enzyme and its D197A catalytic mutant from flash-cooled crystals at 100 K, using synchrotron radiation. These data are currently being used for a high-resolution three-dimensional structure determination of Abp.

  12. Abstract structure of partial function $*$-algebras over semi-direct product of locally compact groups

    Directory of Open Access Journals (Sweden)

    Arash Ghaani Farashahi

    2015-12-01

    Full Text Available This article presents a unified approach to the abstract notions of partial convolution and involution in $L^p$-function spaces over semi-direct product of locally compact groups. Let $H$ and $K$ be locally compact groups and $tau:Hto Aut(K$ be a continuous homomorphism.  Let $G_tau=Hltimes_tau K$ be the semi-direct product of $H$ and $K$ with respect to $tau$. We define left and right $tau$-convolution on $L^1(G_tau$ and we show that, with respect to each of them, the function space $L^1(G_tau$ is a Banach algebra. We define $tau$-convolution as a linear combination of the left and right $tau$-convolution and we show that the $tau$-convolution is commutative if and only if $K$ is abelian. We prove that there is a $tau$-involution on $L^1(G_tau$ such that with respect to the $tau$-involution and $tau$-convolution, $L^1(G_tau$ is a non-associative Banach $*$-algebra. It is also shown that when $K$ is abelian, the $tau$-involution and $tau$-convolution make $L^1(G_tau$ into a Jordan Banach $*$-algebra. Finally, we also present the generalized notation of $tau$-convolution for other $L^p$-spaces with $p>1$.

  13. Simplified analysis of laterally loaded pile groups

    Directory of Open Access Journals (Sweden)

    F.M. Abdrabbo

    2012-06-01

    Full Text Available The response of laterally loaded pile groups is a complicated soil–structure interaction problem. Although fairly reliable methods are developed to predicate the lateral behavior of single piles, the lateral response of pile groups has attracted less attention due to the required high cost and complication implication. This study presents a simplified method to analyze laterally loaded pile groups. The proposed method implements p-multiplier factors in combination with the horizontal modulus of subgrade reaction. Shadowing effects in closely spaced piles in a group were taken into consideration. It is proven that laterally loaded piles embedded in sand can be analyzed within the working load range assuming a linear relationship between lateral load and lateral displacement. The proposed method estimates the distribution of lateral loads among piles in a pile group and predicts the safe design lateral load of a pile group. The benefit of the proposed method is in its simplicity for the preliminary design stage with a little computational effort.

  14. Temperature Increase during Different Post Space Preparation Systems: An In Vitro Study.

    Science.gov (United States)

    Nazari Moghadam, Kiumars; Shahab, Shahriar; Shirvani, Soghra; Kazemi, Ali

    2011-01-01

      The purpose of this study was to evaluate external root surface temperature rise during post space preparation using LA Axxess bur, Beefill pack System, and Peeso Reamer drill. The distal canals of forty-five extracted human permanent mandibular first molars were instrumented in crown-apical manner and obturated with lateral condensation technique. Teeth were then randomly divided into three groups according to post space preparation technique including: group 1. LA Axxess bur (Sybronendo Co., CA, USA), group 2 Beefill pack System (VD W Co., Munich, Germany) and group 3 Peeso Reamer drill (Mani Co., Tochigi-ken, Japan). Temperature was measured by means of digital thermometer MT-405 (Comercio Co., Sao Paulo, Brazil) which was installed on the root surfaces. Data was collected and submitted to one-way ANOVA and Post hoc analysis. Root surface temperatures were found to be significantly higher (7.3±2.7 vs. 4.3±2.1 and 4±2.4,) in samples of Beefill pack System compared with the two other groups (P<0.02). Using Beefill pack System during post space preparation may be potentially hazardous for periodontal tissues.

  15. Methods of Weyl representation of the phase space and canonical transformations

    International Nuclear Information System (INIS)

    Budanov, V.G.

    1986-01-01

    The author studies nonlinear canonical transformations realized in the space of Weyl symbols of quantum operators. The kernels of the transformations, the symbol of the intertwining operator of the group of inhomogeneous point transformations, an the group characters are constructed. The group of PL transformations, which is the free produce of the group of point, p, and linear, L, transformations is considered. The simplest PL complexes relating problems with different potentials, in particular, containing a general Darboux transformation of the factorization method, are constructed. The kernel of an arbitrary element of the group PL is found

  16. Some Diophantine equations from finite group theory: $\\Phi_m (x) = 2p^n -1$

    NARCIS (Netherlands)

    Luca, F.; Moree, P.; Weger, de B.M.M.

    2009-01-01

    We show that the equation in the title (with Fn the nth cyclotomic polynomial) has no integer solution with n = 1 in the cases (m, p) = (15, 41), (15, 5581), (10, 271). These equations arise in a recent group theoretical investigation by Z. Akhlaghi, M. Khatami and B. Khosravi.

  17. Some Diophantine equations from finite group theory: $\\Phi_m (x) = 2p^n -1$

    NARCIS (Netherlands)

    Luca, F.; Moree, P.; Weger, de B.M.M.

    2011-01-01

    We show that the equation in the title (with $\\Psi_m$ the $m$th cyclotomic polynomial) has no integer solution with $n \\geq 1$ in the cases (m,p) = (15,41), (15,5581), (10,271). These equations arise in a recent group theoretical investigation by Akhlaghi, Khosravi and Khatami.

  18. p-Capacity and p-Hyperbolicity of Submanifolds

    DEFF Research Database (Denmark)

    Holopainen, Ilkka; Markvorsen, Steen; Palmer, Vicente

    2009-01-01

    We use explicit solutions to a drifted Laplace equation in warped product model spaces as comparison constructions to show p-hyperbolicity of a large class of submanifolds for p >= 2. The condition for p-hyperbolicity is expressed in terms of upper support functions for the radial sectional curva...

  19. Topology of actions and homogeneous spaces

    International Nuclear Information System (INIS)

    Kozlov, Konstantin L

    2013-01-01

    Topologization of a group of homeomorphisms and its action provide additional possibilities for studying the topological space, the group of homeomorphisms, and their interconnections. The subject of the paper is the use of the property of d-openness of an action (introduced by Ancel under the name of weak micro-transitivity) in the study of spaces with various forms of homogeneity. It is proved that a d-open action of a Čech-complete group is open. A characterization of Polish SLH spaces using d-openness is given, and it is established that any separable metrizable SLH space has an SLH completion that is a Polish space. Furthermore, the completion is realized in coordination with the completion of the acting group with respect to the two-sided uniformity. A sufficient condition is given for extension of a d-open action to the completion of the space with respect to the maximal equiuniformity with preservation of d-openness. A result of van Mill is generalized, namely, it is proved that any homogeneous CDH metrizable compactum is the only G-compactification of the space of rational numbers for the action of some Polish group. Bibliography: 39 titles.

  20. Space Robotics Challenge

    Data.gov (United States)

    National Aeronautics and Space Administration — The Space Robotics Challenge seeks to infuse robot autonomy from the best and brightest research groups in the robotics community into NASA robots for future...

  1. The past and space

    DEFF Research Database (Denmark)

    Lund, Christian

    2013-01-01

    of legitimate forms of land control, complex combinations of claims emerge. The ubiquity of ‘the past’ in African politics and the increasing competition over space suggest that the naturalness with which some refer to the past and others conceive of space should be under constant scrutiny. Based on work...... that competing social elite groups instrumentalize. Each group sees its interests best served by a particular reading of the past and a particular conception of space....

  2. Crystallization and initial X-ray diffraction studies of the flavoenzyme NAD(P)H:(acceptor) oxidoreductase (FerB) from the soil bacterium Paracoccus denitrificans

    International Nuclear Information System (INIS)

    Klumpler, Tomáš; Sedláček, Vojtěch; Marek, Jaromír; Wimmerová, Michaela; Kučera, Igor

    2010-01-01

    The flavin-dependent enzyme FerB from P. denitrificans has been purified and both native and SeMet-substituted FerB have been crystallized. The two variants crystallized in two different crystallographic forms belonging to the monoclinic space group P2 1 and the orthorhombic space group P2 1 2 1 2, respectively. X-ray diffraction data were collected to 1.75 Å resolution for both forms. The flavin-dependent enzyme FerB from Paracoccus denitrificans reduces a broad range of compounds, including ferric complexes, chromate and most notably quinones, at the expense of the reduced nicotinamide adenine dinucleotide cofactors NADH or NADPH. Recombinant unmodified and SeMet-substituted FerB were crystallized under similar conditions by the hanging-drop vapour-diffusion method with microseeding using PEG 4000 as the precipitant. FerB crystallized in several different crystal forms, some of which diffracted to approximately 1.8 Å resolution. The crystals of native FerB belonged to space group P2 1 , with unit-cell parameters a = 61.6, b = 110.1, c = 65.2 Å, β = 118.2° and four protein molecules in the asymmetric unit, whilst the SeMet-substituted form crystallized in space group P2 1 2 1 2, with unit-cell parameters a = 61.2, b = 89.2, c = 71.5 Å and two protein molecules in the asymmetric unit. Structure determination by the three-wavelength MAD/MRSAD method is now in progress

  3. The Effectiveness of a Group Triple P with Chinese Parents Who Have a Child with Developmental Disabilities: A Randomized Controlled Trial

    Science.gov (United States)

    Leung, Cynthia; Fan, Angel; Sanders, Matthew R.

    2013-01-01

    The study examined the effectiveness of Group Triple P, a Level 4 variant of the Triple P multilevel system of parenting support, with Chinese parents who had a preschool aged child with a developmental disability, using randomized controlled trial design. Participants (Intervention group: 42; Waitlist Control group: 39) completed measures on…

  4. Crystallization and preliminary X-ray diffraction analysis of two extracytoplasmic solute receptors of the DctP family from Bordetella pertussis

    International Nuclear Information System (INIS)

    Rucktooa, Prakash; Huvent, Isabelle; Antoine, Rudy; Lecher, Sophie; Jacob-Dubuisson, Françoise; Villeret, Vincent; Bompard, Coralie

    2006-01-01

    Sample preparation, crystallization and preliminary X-ray analysis are reported for two B. pertussis extracytoplasmic solute receptors. DctP6 and DctP7 are two Bordetella pertussis proteins which belong to the extracytoplasmic solute receptors (ESR) superfamily. ESRs are involved in the transport of substrates from the periplasm to the cytosol of Gram-negative bacteria. DctP6 and DctP7 have been crystallized and diffraction data were collected using a synchrotron-radiation source. DctP6 crystallized in space group P4 1 2 1 2, with unit-cell parameters a = 108.39, b = 108.39, c = 63.09 Å, while selenomethionyl-derivatized DctP7 crystallized in space group P2 1 2 1 2 1 , with unit-cell parameters a = 64.87, b = 149.83, c = 170.65 Å. The three-dimensional structure of DctP7 will be determined by single-wavelength anomalous diffraction, while the DctP6 structure will be solved by molecular-replacement methods

  5. Meteor Beliefs Project: Meteoric imagery in SF, Part II - H. P. Lovecraft's The Colour Out Of Space

    Science.gov (United States)

    McBeath, Alastair; Gheorghe, Andrei Dorian

    2005-12-01

    A brief biography of American horror-fiction writer H. P. Lovecraft (1890-1937) precedes details from his story `The Colour Out Of Space', concerning a deadly life-form brought to Earth in a meteorite. This allows a comparison with details from the 1965 film derived from this tale, `Die, Monster, Die!', featuring the great horror actor Boris Karloff in one of his last, best roles.

  6. Space Science at Los Alamos National Laboratory

    Science.gov (United States)

    Smith, Karl

    2017-09-01

    The Space Science and Applications group (ISR-1) in the Intelligence and Space Research (ISR) division at the Los Alamos National Laboratory lead a number of space science missions for civilian and defense-related programs. In support of these missions the group develops sensors capable of detecting nuclear emissions and measuring radiations in space including γ-ray, X-ray, charged-particle, and neutron detection. The group is involved in a number of stages of the lifetime of these sensors including mission concept and design, simulation and modeling, calibration, and data analysis. These missions support monitoring of the atmosphere and near-Earth space environment for nuclear detonations as well as monitoring of the local space environment including space-weather type events. Expertise in this area has been established over a long history of involvement with cutting-edge projects continuing back to the first space based monitoring mission Project Vela. The group's interests cut across a large range of topics including non-proliferation, space situational awareness, nuclear physics, material science, space physics, astrophysics, and planetary physics.

  7. Comparative study of the dust emission of 19P/Borrelly (Deep Space 1) and 1P/Halley

    Science.gov (United States)

    Ho, T.-M.; Thomas, N.; Boice, D.C.; Kollein, C.; Soderblom, L.A.

    2003-01-01

    Images obtained by the Miniature Integrated Camera and Imaging Spectrometer (MICAS) experiment onboard the Deep Space 1 spacecraft which encountered comet 19P/Borrelly on September 22nd 2001 show a dust coma dominated by jets. In particular a major collimated dust jet on the sunward side of the nucleus was observed. Our approach to analyse these features is to integrate the observed intensity in concentric envelopes around the nucleus. The same procedures has been used on the Halley Multicolour Camera images of comet 1P/Halley acquired on March 14th 1986. We are able to show that at Borrelly the dust brightness dependence as a function of radial distance is different to that of Halley. At large distances both comets show constant values as the size of the concentric envelopes increases (as one would expect for force free radial outflow). For Halley the integral decreases as one gets closer to the nucleus. Borrelly shows opposite behaviour. The main cause for Halley's intensity distribution is either high optical thickness or particle fragmentation. For Borrelly, we have constructed a simple model of the brightness distribution near the nucleus. This indicates that the influence of deviations from point source geometry is insufficient to explain the observed steepening of the intensity profile close to the nucleus. Dust acceleration or fragmentation into submicron particles appear to be required. We also estimate the dust production rate of Borrelly with respect to Halley and compare their dust to gas ratios. ?? 2003 COSPAR. Published by Elsevier Ltd. All rights reserved.

  8. q-deformed phase-space and its lattice structure

    International Nuclear Information System (INIS)

    Wess, J.

    1998-01-01

    Quantum groups lead to an algebraic structure that can be realized on quantum spaces. These are non-commutative spaces that inherit a well-defined mathematical structure from the quantum group symmetry. In turn, such quantum spaces can be interpreted as non-commutative configuration spaces for physical systems. We study the non-commutative Euclidean space that is based on the quantum group SO q (3)

  9. Phase equilibria in the Mo-Fe-P system at 800 °C and structure of ternary phosphide (Mo(1-x)Fe(x))3P (0.10 ≤ x ≤ 0.15).

    Science.gov (United States)

    Oliynyk, Anton O; Lomnytska, Yaroslava F; Dzevenko, Mariya V; Stoyko, Stanislav S; Mar, Arthur

    2013-01-18

    Construction of the isothermal section in the metal-rich portion (ternary phases: (Mo(1-x)Fe(x))(2)P (x = 0.30-0.82) and (Mo(1-x)Fe(x))(3)P (x = 0.10-0.15). The occurrence of a Co(2)Si-type ternary phase (Mo(1-x)Fe(x))(2)P, which straddles the equiatomic composition MoFeP, is common to other ternary transition-metal phosphide systems. However, the ternary phase (Mo(1-x)Fe(x))(3)P is unusual because it is distinct from the binary phase Mo(3)P, notwithstanding their similar compositions and structures. The relationship has been clarified through single-crystal X-ray diffraction studies on Mo(3)P (α-V(3)S-type, space group I42m, a = 9.7925(11) Å, c = 4.8246(6) Å) and (Mo(0.85)Fe(0.15))(3)P (Ni(3)P-type, space group I4, a = 9.6982(8) Å, c = 4.7590(4) Å) at -100 °C. Representation in terms of nets containing fused triangles provides a pathway to transform these closely related structures through twisting. Band structure calculations support the adoption of these structure types and the site preference of Fe atoms. Electrical resistivity measurements on (Mo(0.85)Fe(0.15))(3)P reveal metallic behavior but no superconducting transition.

  10. The effects of passive humidifier dead space on respiratory variables in paralyzed and spontaneously breathing patients.

    Science.gov (United States)

    Campbell, R S; Davis, K; Johannigman, J A; Branson, R D

    2000-03-01

    Passive humidifiers have gained acceptance in the intensive care unit because of their low cost, simple operation, and elimination of condensate from the breathing circuit. However, the additional dead space of these devices may adversely affect respiratory function in certain patients. This study evaluates the effects of passive humidifier dead space on respiratory function. Two groups of patients were studied. The first group consisted of patients recovering from acute lung injury and breathing spontaneously on pressure support ventilation. The second group consisted of patients who were receiving controlled mechanical ventilation and were chemically paralyzed following operative procedures. All patients used 3 humidification devices in random order for one hour each. The devices were a heated humidifier (HH), a hygroscopic heat and moisture exchanger (HHME) with a dead space of 28 mL, and a heat and moisture exchanger (HME) with a dead space of 90 mL. During each measurement period the following were recorded: tidal volume, minute volume, respiratory frequency, oxygen consumption, carbon dioxide production, ratio of dead space volume to tidal volume (VD/VT), and blood gases. In the second group, intrinsic positive end-expiratory pressure was also measured. Addition of either of the passive humidifiers was associated with increased VD/VT. In spontaneously breathing patients, VD/VT increased from 59 +/- 13 (HH) to 62 +/- 13 (HHME) to 68 +/- 11% (HME) (p < 0.05). In these patients, constant alveolar ventilation was maintained as a result of increased respiratory frequency, from 22.1 +/- 6.6 breaths/min (HH) to 24.5 +/- 6.9 breaths/min (HHME) to 27.7 +/- 7.4 breaths/min (HME) (p < 0.05), and increased minute volume, from 9.1 +/- 3.5 L/min (HH) to 9.9 +/- 3.6 L/min (HHME) to 11.7 +/- 4.2 L/min (HME) (p < 0.05). There were no changes in blood gases or carbon dioxide production. In the paralyzed patient group, VD/VT increased from 54 +/- 12% (HH) to 56 +/- 10% (HHME

  11. Wigner functions from the two-dimensional wavelet group.

    Science.gov (United States)

    Ali, S T; Krasowska, A E; Murenzi, R

    2000-12-01

    Following a general procedure developed previously [Ann. Henri Poincaré 1, 685 (2000)], here we construct Wigner functions on a phase space related to the similitude group in two dimensions. Since the group space in this case is topologically homeomorphic to the phase space in question, the Wigner functions so constructed may also be considered as being functions on the group space itself. Previously the similitude group was used to construct wavelets for two-dimensional image analysis; we discuss here the connection between the wavelet transform and the Wigner function.

  12. Homogeneous Spaces and Equivariant Embeddings

    CERN Document Server

    Timashev, DA

    2011-01-01

    Homogeneous spaces of linear algebraic groups lie at the crossroads of algebraic geometry, theory of algebraic groups, classical projective and enumerative geometry, harmonic analysis, and representation theory. By standard reasons of algebraic geometry, in order to solve various problems on a homogeneous space it is natural and helpful to compactify it keeping track of the group action, i.e. to consider equivariant completions or, more generally, open embeddings of a given homogeneous space. Such equivariant embeddings are the subject of this book. We focus on classification of equivariant em

  13. WebVR——Web Virtual Reality Engine Based on P2P network

    OpenAIRE

    zhihan LV; Tengfei Yin; Yong Han; Yong Chen; Ge Chen

    2011-01-01

    WebVR, a multi-user online virtual reality engine, is introduced. The main contributions are mapping the geographical space and virtual space to the P2P overlay network space, and dividing the three spaces by quad-tree method. The geocoding is identified with Hash value, which is used to index the user list, terrain data, and the model object data. Sharing of data through improved Kademlia network model is designed and implemented. In this model, XOR algorithm is used to calculate the distanc...

  14. [Secondary male hypogonadism induced by sellar space-occupying lesion: Clinical analysis of 22 cases].

    Science.gov (United States)

    Lu, Hong-Lei; Wang, Tao; Xu, Hao; Chen, Li-Ping; Rao, Ke; Yang, Jun; Yuan, Hui-Xing; Liu, Ji-Hong

    2016-08-01

    To analyze the clinical characteristics of secondary male hypogonadism induced by sellar space-occupying lesion, explore its pathogenesis, and improve its diagnosis and treatment. We retrospectively analyzed the clinical data about 22 cases of secondary male hypogonadism induced by sellar space-occupying lesion, reviewed related literature, and investigated the clinical manifestation, etiological factors, and treatment methods of the disease. Hypogonadism developed in 10 of the patients before surgery and radiotherapy (group A) and in the other 12 after it (group B). The patients received endocrine therapy with Andriol (n=7) or hCG (n=15). The average diameter of the sellar space-occupying lesions was significantly longer in group A than in B ([2.35±0.71] vs [1.83±0.36] cm, P<0.05) and the incidence rate of prolactinomas was markedly higher in the former than in the latter group (60% vs 0, P<0.01). The levels of lutein hormone (LH), follicle stimulating hormone (FSH) and testosterone (T) were remarkably decreased in group B after surgery and radiotherapy (P<0.01). Compared with the parameters obtained before endocrine therapy, all the patients showed significant increases after intervention with Andriol or hCG in the T level ([0.78±0.40] vs [2.71±0.70] ng/ml with Andriol; [0.93±0.44] vs [3.07±0.67] ng/ml with hCG) and IIEF-5 score (5.00±2.61 vs 14.50±3.62 with Andriol; 5.36±1.82 vs 15.07±3.27 with hCG) (all P<0.01). The testis volume increased and pubic hair began to grow in those with hypoevolutism. The patients treated with hCG showed a significantly increased testis volume (P<0.01) and sperm was detected in 7 of them, whose baseline testis volume was markedly larger than those that failed to produce sperm ([11.5±2.3] vs [7.5±2.3] ml, P<0.01). Those treated with Andriol exhibited no significant difference in the testis volume before and after intervention and produced no sperm, either. Hypothyroidism might be attributed

  15. INFLUENCE OF ECOLOGICAL GROUP COMPOSITION, PLANTATION SPACING AND ARRANGEMENT IN THE RESTORATION OF RIPARIAN FOREST ON RESERVOIR SHORES

    Directory of Open Access Journals (Sweden)

    Alvaro Augusto Vieira Soares

    2016-01-01

    Full Text Available This work aimed to assess the effect of spacing, arrangement and ecological group composition of planted seedlings on the restoration process of artificial reservoir shores in southeastern Brazil. The assessments were performed 12 years after the settlement of the experiment in which five mixed stand models were tested. First, a general evaluation of the stand was performed when we surveyed the overstory and understory, seed bank and soil for chemical analysis.Then, the restoration indicators survival of planted trees, basal area and density of the tree community, litter accumulated on the soil and canopy closure index were utilized to compare the plantation models and to assess the influence the experimental factors on these parameters. In the general analysis, we found that the studied stand presents low diversity, poor regeneration, and seed bank dominated mostly by one planted exotic tree species and weeds, which may jeopardize the self- maintenance of the stand in the future. The factor that most influenced the models was the ecological group composition with the best performance found for models in which both pioneer and non-pioneer groups were used. Probably, the plantation arrangement and spacing did not have greater influence due to both plant mortality and natural regeneration that has developed to this age. Hence, it is not recommended the use of only pioneer species in the implantation of riparian forest and the proportion of 50% pioneers and 50% non-pioneers using as much species as possible is indicated for areas that might present constraints for the natural regeneration.

  16. A new class of Banach spaces

    International Nuclear Information System (INIS)

    Gill, T L; Zachary, W W

    2008-01-01

    In this paper, we construct a new class of separable Banach spaces KS p , for 1 ≤ p ≤ ∞, each of which contains all of the standard L p spaces, as well as the space of finitely additive measures, as compact dense embeddings. Equally important is the fact that these spaces contain all Henstock-Kurzweil integrable functions and, in particular, the Feynman kernel and the Dirac measure, as norm bounded elements. As a first application, we construct the elementary path integral in the manner originally intended by Feynman. We then suggest that KS 2 is a more appropriate Hilbert space for quantum theory, in that it satisfies the requirements for the Feynman, Heisenberg and Schroedinger representations, while the conventional choice only satisfies the requirements for the Heisenberg and Schroedinger representations. As a second application, we show that the mixed topology on the space of bounded continuous functions, C b [R n ], used to define the weak generator for a semigroup T(t), is stronger than the norm topology on KS p . (This means that, when extended to KS p , T(t) is strongly continuous, so that the weak generator on C b [R n ] becomes a strong generator on KS p .)

  17. Functional Groups Determine Biochar Properties (pH and EC as Studied by Two-Dimensional (13C NMR Correlation Spectroscopy.

    Directory of Open Access Journals (Sweden)

    Xiaoming Li

    Full Text Available While the properties of biochar are closely related to its functional groups, it is unclear under what conditions biochar develops its properties. In this study, two-dimensional (2D (13C nuclear magnetic resonance (NMR correlation spectroscopy was for the first time applied to investigate the development of functional groups and establish their relationship with biochar properties. The results showed that the agricultural biomass carbonized to biochars was a dehydroxylation/dehydrogenation and aromatization process, mainly involving the cleavage of O-alkylated carbons and anomeric O-C-O carbons in addition to the production of fused-ring aromatic structures and aromatic C-O groups. With increasing charring temperature, the mass cleavage of O-alkylated groups and anomeric O-C-O carbons occurred prior to the production of fused-ring aromatic structures. The regression analysis between functional groups and biochar properties (pH and electrical conductivity further demonstrated that the pH and electrical conductivity of rice straw derived biochars were mainly determined by fused-ring aromatic structures and anomeric O-C-O carbons, but the pH of rice bran derived biochars was determined by both fused-ring aromatic structures and aliphatic O-alkylated (HCOH carbons. In summary, this work suggests a novel tool for characterising the development of functional groups in biochars.

  18. The projectable hull of an archimedean $ell$-group with weak unit

    Directory of Open Access Journals (Sweden)

    Anthony W. Hager

    2017-07-01

    Full Text Available The much-studied projectable hull of an $ell$-group $Gleq pG$ is an essential extension, so that, in the case that $G$ is  archimedean with weak unit, ``$Gin {bf W}$", we have for the Yosida representation spaces a ``covering map" $YG leftarrow YpG$. We have earlier cite{hkm2} shown that (1 this cover has a characteristic minimality property, and that (2 knowing $YpG$, one can write down $pG$. We now show directly that for $mathscr{A}$, the boolean algebra in the power set of the minimal prime spectrum $Min(G$, generated by the sets $U(g={Pin Min(G:gnotin P}$ ($gin G$, the Stone space $mathcal{A}mathscr{A}$ is a cover of $YG$ with the minimal property of (1; this extends the result from cite{bmmp} for the strong unit case. Then, applying (2 gives the pre-existing description of $pG$, which includes the strong unit description of cite{bmmp}. The present methods are largely topological, involving details of covering maps and Stone duality.

  19. The character of free topological groups II

    Directory of Open Access Journals (Sweden)

    Peter Nickolas

    2005-04-01

    Full Text Available A systematic analysis is made of the character of the free and free abelian topological groups on metrizable spaces and compact spaces, and on certain other closely related spaces. In the first case, it is shown that the characters of the free and the free abelian topological groups on X are both equal to the “small cardinal” d if X is compact and metrizable, but also, more generally, if X is a non-discrete k!-space all of whose compact subsets are metrizable, or if X is a non-discrete Polish space. An example is given of a zero-dimensional separable metric space for which both characters are equal to the cardinal of the continuum. In the case of a compact space X, an explicit formula is derived for the character of the free topological group on X involving no cardinal invariant of X other than its weight; in particular the character is fully determined by the weight in the compact case. This paper is a sequel to a paper by the same authors in which the characters of the free groups were analysed under less restrictive topological assumptions.

  20. New lanthanide hydrogen phosphites LnH (P03H)2 2H20

    International Nuclear Information System (INIS)

    Durand, J.; Tijani, N.; Cot, L.; Loukili, M.; Rafiq, M.

    1988-01-01

    LnH ((P0 3 H) 2 2H 2 0 is prepared from lanthanide oxide and phosphorous acid with Ln = La, Y, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er or Tm. By thermal gravimetric analysis LnH (P0 3 H) 2 and LnH 2 P 2 0 5 (P0 3 H) 2 are obtained. The three salts are orthorhombic. Parameters and space groups are given for the three salts of each lanthanide. 4 tabs., 13 refs

  1. Geometrical aspects of quantum spaces

    International Nuclear Information System (INIS)

    Ho, P.M.

    1996-01-01

    Various geometrical aspects of quantum spaces are presented showing the possibility of building physics on quantum spaces. In the first chapter the authors give the motivations for studying noncommutative geometry and also review the definition of a Hopf algebra and some general features of the differential geometry on quantum groups and quantum planes. In Chapter 2 and Chapter 3 the noncommutative version of differential calculus, integration and complex structure are established for the quantum sphere S 1 2 and the quantum complex projective space CP q (N), on which there are quantum group symmetries that are represented nonlinearly, and are respected by all the aforementioned structures. The braiding of S q 2 and CP q (N) is also described. In Chapter 4 the quantum projective geometry over the quantum projective space CP q (N) is developed. Collinearity conditions, coplanarity conditions, intersections and anharmonic ratios is described. In Chapter 5 an algebraic formulation of Reimannian geometry on quantum spaces is presented where Riemannian metric, distance, Laplacian, connection, and curvature have their quantum counterparts. This attempt is also extended to complex manifolds. Examples include the quantum sphere, the complex quantum projective space and the two-sheeted space. The quantum group of general coordinate transformations on some quantum spaces is also given

  2. Quantum field theory with a momentum space of constant curvature (perturbation theory)

    International Nuclear Information System (INIS)

    Mir-Kasimov, R.M.

    1978-01-01

    In the framework of the field-theoretical approach in which the off-the-mass shell extension proceeds in the p-space of constant curvature, the perburbation theory is developed. The configurational representation of the de Sitter space is introduced with the help of the Fourier transformation of the group of motions. On the basis of a natural generalization of the Bogolyubov causality condition to the case of the new configurational representation a perturbation theory is constructed with the local in xi space Lagrangian density fucntion. The obtained S matrix obeys the reguirement of translation invariance. The S matrix elements are given by convergent expressions

  3. Abelian varieties and p-divisible groups

    NARCIS (Netherlands)

    Oort, F.

    2005-01-01

    Yuri Manin’s Emeritierung Conference 24 – 26 February 2005 It is nice to give a talk at this event on the influential paper: [M] Yu. I. Manin – The theory of commutative formal groups over fields of finite characteristic. Usp. Math. 18 (1963), 3-90; Russ. Math. Surveys 18 (1963), 1-80.

  4. Polycomb Group Protein PHF1 Regulates p53-dependent Cell Growth Arrest and Apoptosis*

    Science.gov (United States)

    Yang, Yang; Wang, Chenji; Zhang, Pingzhao; Gao, Kun; Wang, Dejie; Yu, Hongxiu; Zhang, Ting; Jiang, Sirui; Hexige, Saiyin; Hong, Zehui; Yasui, Akira; Liu, Jun O.; Huang, Haojie; Yu, Long

    2013-01-01

    Polycomb group protein PHF1 is well known as a component of a novel EED-EZH2·Polycomb repressive complex 2 complex and plays important roles in H3K27 methylation and Hox gene silencing. PHF1 is also involved in the response to DNA double-strand breaks in human cells, promotes nonhomologous end-joining processes through interaction with Ku70/Ku80. Here, we identified another function of PHF1 as a potential p53 pathway activator in a pathway screen using luminescence reporter assay. Subsequent studies showed PHF1 directly interacts with p53 proteins both in vivo and in vitro and co-localized in nucleus. PHF1 binds to the C-terminal regulatory domain of p53. Overexpression of PHF1 elevated p53 protein level and prolonged its turnover. Knockdown of PHF1 reduced p53 protein level and its target gene expression both in normal state and DNA damage response. Mechanically, PHF1 protects p53 proteins from MDM2-mediated ubiquitination and degradation. Furthermore, we showed that PHF1 regulates cell growth arrest and etoposide-induced apoptosis in a p53-dependent manner. Finally, PHF1 expression was significantly down-regulated in human breast cancer samples. Taken together, we establish PHF1 as a novel positive regulator of the p53 pathway. These data shed light on the potential roles of PHF1 in tumorigenesis and/or tumor progression. PMID:23150668

  5. Ge 3P 6Si 2O 25: A cage structure closely related to the intersecting tunnel structure KMo 3P 6Si 2O 25

    Science.gov (United States)

    Leclaire, A.; Raveau, B.

    1988-08-01

    A germanosilicophosphate Ge 3P 6Si 2O 25 has been isolated. Its structure was solved from a single-crystal study in the space group P overline31c . Its cell parameters are a = b = 7.994(1) Å, c = 16.513(2) Å, Z = 2. The refinement by full-matrix least-squares calculations leads to R = 0.043 with 686 independent reflections. The structure of this oxide is built up from corner-sharing PO 4 and SiO 4 tetrahedra and GeO 6 octahedra. One observes a feature common to several silicophosphates: the presence of the structural unit P 6Si 2O 25 built up from a disilicate group sharing its corners with six PO 4 tetrahedra. The structural relationships between this oxide and the silicophosphates AMo 3P 6Si 2O 25 and Si 3P 6Si 2O 25 (or Ge 3P 6 Ge 2O 25) are described.

  6. Theory of function spaces

    CERN Document Server

    Triebel, Hans

    1983-01-01

    The book deals with the two scales Bsp,q and Fsp,q of spaces of distributions, where -8p,q=8, which include many classical and modern spaces, such as Hölder spaces, Zygmund classes, Sobolev spaces, Besov spaces, Bessel-potential spaces, Hardy spaces and spaces of BMO-type. It is the main aim of this book to give a unified treatment of the corresponding spaces on the Euclidean n-space Rn in the framework of Fourier analysis, which is based on the technique of maximal functions, Fourier multipliers and interpolation assertions. These topics are treated in Chapter 2, which is the heart

  7. Dielectric relaxation and ionic conductivity studies of Na2ZnP2O7

    Indian Academy of Sciences (India)

    Administrator

    compound crystallized in the tetragonal system with the space group P42/n and ... Philips PW 1710 diffractometer operating with copper radiation Kα = 1⋅5418 Å. .... between mobile ions and the environments surrounding them. The transport ...

  8. Space for Interaction

    DEFF Research Database (Denmark)

    Jørgensen, Mariane Ellen; Folmer, Mette Blicher; Mullins, Michael

    SPACE FOR INTERACTION QUALIFYING GROUP TREATMENT FOR PATIENTS WITH CHRONIC PAIN THROUGH OPTIMIZATION(?) OF SPACE. A RANDOMIZED PILOT STUDY. In a Ph-D. Mariane Ellen Jørgensen / Nurse + psykoterapist / maej@rn.dk / Pain Center / Aalborg University Hospital / Denmark / Mette Blicher Folmer / Archit...

  9. Crystallization and preliminary X-ray diffraction analysis of two extracytoplasmic solute receptors of the DctP family from Bordetella pertussis

    Energy Technology Data Exchange (ETDEWEB)

    Rucktooa, Prakash; Huvent, Isabelle [UMR8161 CNRS Institut de Biologie de Lille, Laboratoire de Cristallographie Macromoléculaire, 1 Rue du Professeur Calmette, BP 447, 59021 Lille CEDEX (France); IFR 142, Institut Pasteur de Lille, 1 Rue du Professeur Calmette, BP 245, 59021 Lille CEDEX (France); Antoine, Rudy; Lecher, Sophie; Jacob-Dubuisson, Françoise, E-mail: francoise.jacob@ibl.fr [IFR 142, Institut Pasteur de Lille, 1 Rue du Professeur Calmette, BP 245, 59021 Lille CEDEX (France); INSERM-U629, Lille (France); Institut Pasteur de Lille, 1 Rue du Professeur Calmette, BP 245, 59021 Lille CEDEX (France); Villeret, Vincent, E-mail: francoise.jacob@ibl.fr; Bompard, Coralie [UMR8161 CNRS Institut de Biologie de Lille, Laboratoire de Cristallographie Macromoléculaire, 1 Rue du Professeur Calmette, BP 447, 59021 Lille CEDEX (France); IFR 142, Institut Pasteur de Lille, 1 Rue du Professeur Calmette, BP 245, 59021 Lille CEDEX (France)

    2006-10-01

    Sample preparation, crystallization and preliminary X-ray analysis are reported for two B. pertussis extracytoplasmic solute receptors. DctP6 and DctP7 are two Bordetella pertussis proteins which belong to the extracytoplasmic solute receptors (ESR) superfamily. ESRs are involved in the transport of substrates from the periplasm to the cytosol of Gram-negative bacteria. DctP6 and DctP7 have been crystallized and diffraction data were collected using a synchrotron-radiation source. DctP6 crystallized in space group P4{sub 1}2{sub 1}2, with unit-cell parameters a = 108.39, b = 108.39, c = 63.09 Å, while selenomethionyl-derivatized DctP7 crystallized in space group P2{sub 1}2{sub 1}2{sub 1}, with unit-cell parameters a = 64.87, b = 149.83, c = 170.65 Å. The three-dimensional structure of DctP7 will be determined by single-wavelength anomalous diffraction, while the DctP6 structure will be solved by molecular-replacement methods.

  10. Characteristics of the groups of charged particles in bar pp,pp and K-p interactions at 32 GeV/c

    International Nuclear Information System (INIS)

    Bogolubsky, M.Yu.; Levitsky, M.S.; Maksimov, V.V.

    1995-01-01

    In the clan model, a method is developed for determining the following characteristics of the groups of charged particles: group multiplicity in an interval, particle multiplicity in a group, and width distribution of groups. Distribution densities are obtained for particles originating from clans produced at a given rapidity point with given width in bar pp, K - p, and pp interactions at 32 GeV/c. It is shown that the differences in the rate of growth of factorial moments in bar pp and K - p interactions are due to a difference in the relative contributions of small-width clans. 12 refs., 13 figs., 2 tabs

  11. Report of space experiment project, 'Rad Gene', performed in the International Space Station Kibo

    International Nuclear Information System (INIS)

    Ohnishi, Takeo; Takahashi, Akihisa; Nagamatsu, Aiko

    2010-01-01

    This report summarizes results of the project in the title adopted by Japan Aerospace Exploration Agency (JAXA) (in 2000) aiming to elucidate the biological effect of space environment, and contains 3 major parts of the process of the experiment, and of findings by analysis after flight and in radioadaptive response. The process for the experiment includes training of the experimenter crew (Dr. S. Magnus) in JAXA, preparation of samples (frozen cells with normal and mutated p53 genes derived from human lymphoblast TK6) and their transfer to the Space Shuttle Endeavour STS-126 launched on Nov. 15, 2008 (Japanese time) for cell culturing in Feb., 2009. Analyses after flight back to the Kennedy Space Center on Mar. 29, 2009, done on the ground in Japan thereafter include the physical evaluation, confirmation of DNA damage, and phenotypic expression with DNA- and protein-arrays (genes induced for expression of p53-related phenotypes in those cells which were stored frozen in the space, thawed on the ground and then cultured, genes induced for expressing the phenotypes and p53-related proteins expressed in cells cultured in space). Physically, total absorbed dose and dose equivalent are found to be respectively 43.5 mGy and 71.2 mSv (0.5 mSv/day). Interestingly, the biologically estimated dose by DNA-double strand breaks detected by γH2AX staining, 94.5 mSv (0.7 mSv/day), in living, frozen cells in space, is close to the above physical dose. Expression experiments of p53-related phenotypes have revealed that expression of 750 or more genes in 41,000 genes in the array is changed: enhanced or suppressed by space radiation, micro-gravity and/or their mixed effects in space environment. In 642 protein antibodies in the array, 2 proteins are found enhanced and 8, suppressed whereas heat-shock protein is unchanged. Radioadaptive response is the acquisition of radio-resistance to acute exposure by previous irradiation of small dose (window width 20-100 mSv) in normal p53

  12. Crystal structure of dimethylformamidium bis(trifluoromethanesulfonylamide: an ionic liquid

    Directory of Open Access Journals (Sweden)

    Allan Jay P. Cardenas

    2016-09-01

    Full Text Available At 100 K, the title molecular salt, C3H8NO+·C2F6NO4S2−, has orthorhombic (P212121 symmetry; the amino H atom of bis(trifluoromethanesulfonylamine (HNTf2 was transferred to the basic O atom of dimethylformamide (DMF when the ionic liquid components were mixed. The structure displays an O—H...N hydrogen bond, which links the cation to the anion, which is reinforced by a non-conventional C—H...O interaction, generating an R22(7 loop. A further very weak C—H...O interaction generates an [001] chain.

  13. Dynamics of infinite-dimensional groups the Ramsey-Dvoretzky-Milman phenomenon

    CERN Document Server

    Pestov, Vladimir

    2006-01-01

    The "infinite-dimensional groups" in the title refer to unitary groups of Hilbert spaces, the infinite symmetric group, groups of homeomorphisms of manifolds, groups of transformations of measure spaces, etc. The book presents an approach to the study of such groups based on ideas from geometric functional analysis and from exploring the interplay between dynamical properties of those groups, combinatorial Ramsey-type theorems, and the phenomenon of concentration of measure. The dynamics of infinite-dimensional groups is very much unlike that of locally compact groups. For instance, every locally compact group acts freely on a suitable compact space (Veech). By contrast, a 1983 result by Gromov and Milman states that whenever the unitary group of a separable Hilbert space continuously acts on a compact space, it has a common fixed point. In the book, this new fast-growing theory is built strictly from well-understood examples up. The book has no close counterpart and is based on recent research articles. At t...

  14. Absence of renormalization group pathologies near the critical temperature. Two examples

    International Nuclear Information System (INIS)

    Haller, K.; Kennedy, T.

    1996-01-01

    We consider real-space renormalization group transformations for Ising-type systems which are formally defined by where T(σ, σ') is a probability kernel, i.e., Σ σ' T(σ, σ') = 1, for every configuration σ. For each choice of the block spin configuration σ', let μ σ' , be the measure on spin configurations σ which is formally given by taking the probability of σ to be proportional to T(σ, σ') exp[ -H(σ)]. We give a condition which is sufficient to imply that the renormalized Hamiltonian H' is defined. Roughly speaking, the condition is that the collection of measures μ σ' is in the high-temperature phase uniformly in the block spin configuration σ'. The proof of this result uses methods of Olivieri and Picco. We use our theorem to prove that the first iteration of the renormalization group transformation is defined in the following two examples: decimation with spacing b = 2 on the square lattice with β c and the Kadanoff transformation with parameter p on the triangular lattice in a subset of the β, p plane that includes values of β greater than β c

  15. A Third-Order p-Laplacian Boundary Value Problem Solved by an SL(3,ℝ Lie-Group Shooting Method

    Directory of Open Access Journals (Sweden)

    Chein-Shan Liu

    2013-01-01

    Full Text Available The boundary layer problem for power-law fluid can be recast to a third-order p-Laplacian boundary value problem (BVP. In this paper, we transform the third-order p-Laplacian into a new system which exhibits a Lie-symmetry SL(3,ℝ. Then, the closure property of the Lie-group is used to derive a linear transformation between the boundary values at two ends of a spatial interval. Hence, we can iteratively solve the missing left boundary conditions, which are determined by matching the right boundary conditions through a finer tuning of r∈[0,1]. The present SL(3,ℝ Lie-group shooting method is easily implemented and is efficient to tackle the multiple solutions of the third-order p-Laplacian. When the missing left boundary values can be determined accurately, we can apply the fourth-order Runge-Kutta (RK4 method to obtain a quite accurate numerical solution of the p-Laplacian.

  16. Causal symmetric spaces

    CERN Document Server

    Olafsson, Gestur; Helgason, Sigurdur

    1996-01-01

    This book is intended to introduce researchers and graduate students to the concepts of causal symmetric spaces. To date, results of recent studies considered standard by specialists have not been widely published. This book seeks to bring this information to students and researchers in geometry and analysis on causal symmetric spaces.Includes the newest results in harmonic analysis including Spherical functions on ordered symmetric space and the holmorphic discrete series and Hardy spaces on compactly casual symmetric spacesDeals with the infinitesimal situation, coverings of symmetric spaces, classification of causal symmetric pairs and invariant cone fieldsPresents basic geometric properties of semi-simple symmetric spacesIncludes appendices on Lie algebras and Lie groups, Bounded symmetric domains (Cayley transforms), Antiholomorphic Involutions on Bounded Domains and Para-Hermitian Symmetric Spaces

  17. Inner Functions in Lipschitz, Besov, and Sobolev Spaces

    Directory of Open Access Journals (Sweden)

    Daniel Girela

    2011-01-01

    Full Text Available We study the membership of inner functions in Besov, Lipschitz, and Hardy-Sobolev spaces, finding conditions that enable an inner function to be in one of these spaces. Several results in this direction are given that complement or extend previous works on the subject from different authors. In particular, we prove that the only inner functions in either any of the Hardy-Sobolev spacesp with 1/p≤α<∞ or any of the Besov spacesp,  q with 0<p,q≤∞ and α≥1/p, except when p=∞, α=0, and 2p<∞, q=∞, and α=1/p are finite Blaschke products. Our assertion for the spaces B0∞,q, 0space VMOA. We prove also that for 2space contains infinite Blaschke products. Furthermore, we obtain distinct results for other values of α relating the membership of an inner function I in the spaces under consideration with the distribution of the sequences of preimages {I-1(a}, |a|<1. In addition, we include a section devoted to Blaschke products with zeros in a Stolz angle.

  18. On infinite-dimensional state spaces

    International Nuclear Information System (INIS)

    Fritz, Tobias

    2013-01-01

    It is well known that the canonical commutation relation [x, p]=i can be realized only on an infinite-dimensional Hilbert space. While any finite set of experimental data can also be explained in terms of a finite-dimensional Hilbert space by approximating the commutation relation, Occam's razor prefers the infinite-dimensional model in which [x, p]=i holds on the nose. This reasoning one will necessarily have to make in any approach which tries to detect the infinite-dimensionality. One drawback of using the canonical commutation relation for this purpose is that it has unclear operational meaning. Here, we identify an operationally well-defined context from which an analogous conclusion can be drawn: if two unitary transformations U, V on a quantum system satisfy the relation V −1 U 2 V=U 3 , then finite-dimensionality entails the relation UV −1 UV=V −1 UVU; this implication strongly fails in some infinite-dimensional realizations. This is a result from combinatorial group theory for which we give a new proof. This proof adapts to the consideration of cases where the assumed relation V −1 U 2 V=U 3 holds only up to ε and then yields a lower bound on the dimension.

  19. On infinite-dimensional state spaces

    Science.gov (United States)

    Fritz, Tobias

    2013-05-01

    It is well known that the canonical commutation relation [x, p] = i can be realized only on an infinite-dimensional Hilbert space. While any finite set of experimental data can also be explained in terms of a finite-dimensional Hilbert space by approximating the commutation relation, Occam's razor prefers the infinite-dimensional model in which [x, p] = i holds on the nose. This reasoning one will necessarily have to make in any approach which tries to detect the infinite-dimensionality. One drawback of using the canonical commutation relation for this purpose is that it has unclear operational meaning. Here, we identify an operationally well-defined context from which an analogous conclusion can be drawn: if two unitary transformations U, V on a quantum system satisfy the relation V-1U2V = U3, then finite-dimensionality entails the relation UV-1UV = V-1UVU; this implication strongly fails in some infinite-dimensional realizations. This is a result from combinatorial group theory for which we give a new proof. This proof adapts to the consideration of cases where the assumed relation V-1U2V = U3 holds only up to ɛ and then yields a lower bound on the dimension.

  20. Features of Virchow-Robin spaces in newly diagnosed multiple sclerosis patients

    Energy Technology Data Exchange (ETDEWEB)

    Etemadifar, Masoud [Department of Clinical and Biological Sciences, Division of Neurology, San Luigi Gonzaga School of Medicine, Orbassano (Torino), Turin (Italy); Department of Neurology, Isfahan University of Medical Sciences, Isfahan (Iran, Islamic Republic of); Isfahan Research Committee of Multiple Sclerosis (IRCOMS), Isfahan University of Medical Sciences, Isfahan (Iran, Islamic Republic of); Hekmatnia, Ali; Tayari, Nazila [Department of Radiology, Isfahan University of Medical Sciences, Isfahan (Iran, Islamic Republic of); Kazemi, Mojtaba [Department of Neurology, Isfahan University of Medical Sciences, Isfahan (Iran, Islamic Republic of); Ghazavi, Amirhossein [Department of Radiology, Isfahan University of Medical Sciences, Isfahan (Iran, Islamic Republic of); Akbari, Mojtaba [Department of Epidemiology and Statistics, Isfahan University of Medical Sciences, Isfahan (Iran, Islamic Republic of); Maghzi, Amir-Hadi, E-mail: maghzi@edc.mui.ac.ir [Isfahan Research Committee of Multiple Sclerosis (IRCOMS), Isfahan University of Medical Sciences, Isfahan (Iran, Islamic Republic of); Neuroimmunology Unit, Centre for Neuroscience and Trauma, Blizard Institute of Cell and Molecular Science, Barts and the London School of Medicine and Dentistry, London (United Kingdom); Isfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Isfahan (Iran, Islamic Republic of)

    2011-11-15

    Background: Virchow-Robin spaces (VRSs) are perivascular pia-lined extensions of the subarachnoid space around the arteries and veins as they enter the brain parenchyma. These spaces are responsible for inflammatory processes within the brain. Objectives: This study was designed to shed more light on the location, size and shape of VRSs on 3 mm slice thickness, 1.5 Tesla MRI scans of newly diagnosed MS patients in Isfahan, Iran and compare the results with healthy age- and sex-matched controls. Methods: We evaluated MRI scans of 73 MS patients obtained within 3 months of MS onset and compared them with MRI scans from 73 age- and sex-matched healthy volunteers. Three mm section proton density, T2W and FLAIR MR images were obtained for all subjects. The location, size and shape of VRSs were compared between the two groups. Results: The total number of VRSs was significantly more in the MS group (p < 0.001). The distribution of VRSs were significantly more located in the high convexity areas in the MS group (p < 0.001), while there was no significant differences in other regions. The round shaped VRSs were significantly more detected on MRI scans of MS patients, and curvilinear shapes were significantly more frequently observed in healthy volunteers, however there were no significant differences for oval shaped VRSs between the two groups. The number of VRSs with the size over than 2 mm were significantly more observed in the MS groups compared to controls. We also observed some differences in the characteristics of VRSs between the genders in the MS group. Conclusion: The results of this study shed more light on the usefulness of VRSs as an MRI marker for the disease. In addition, according to our results VRSs might also have implication to determine the prognosis of the disease. However, larger studies with more advanced MRI techniques are required to confirm our results.

  1. Features of Virchow-Robin spaces in newly diagnosed multiple sclerosis patients

    International Nuclear Information System (INIS)

    Etemadifar, Masoud; Hekmatnia, Ali; Tayari, Nazila; Kazemi, Mojtaba; Ghazavi, Amirhossein; Akbari, Mojtaba; Maghzi, Amir-Hadi

    2011-01-01

    Background: Virchow-Robin spaces (VRSs) are perivascular pia-lined extensions of the subarachnoid space around the arteries and veins as they enter the brain parenchyma. These spaces are responsible for inflammatory processes within the brain. Objectives: This study was designed to shed more light on the location, size and shape of VRSs on 3 mm slice thickness, 1.5 Tesla MRI scans of newly diagnosed MS patients in Isfahan, Iran and compare the results with healthy age- and sex-matched controls. Methods: We evaluated MRI scans of 73 MS patients obtained within 3 months of MS onset and compared them with MRI scans from 73 age- and sex-matched healthy volunteers. Three mm section proton density, T2W and FLAIR MR images were obtained for all subjects. The location, size and shape of VRSs were compared between the two groups. Results: The total number of VRSs was significantly more in the MS group (p < 0.001). The distribution of VRSs were significantly more located in the high convexity areas in the MS group (p < 0.001), while there was no significant differences in other regions. The round shaped VRSs were significantly more detected on MRI scans of MS patients, and curvilinear shapes were significantly more frequently observed in healthy volunteers, however there were no significant differences for oval shaped VRSs between the two groups. The number of VRSs with the size over than 2 mm were significantly more observed in the MS groups compared to controls. We also observed some differences in the characteristics of VRSs between the genders in the MS group. Conclusion: The results of this study shed more light on the usefulness of VRSs as an MRI marker for the disease. In addition, according to our results VRSs might also have implication to determine the prognosis of the disease. However, larger studies with more advanced MRI techniques are required to confirm our results.

  2. Fock model and Segal-Bargmann transform for minimal representations of Hermitian Lie groups

    DEFF Research Database (Denmark)

    Hilgert, Joachim; Kobayashi, Toshiyuki; Möllers, Jan

    2012-01-01

    For any Hermitian Lie group G of tube type we construct a Fock model of its minimal representation. The Fock space is defined on the minimal nilpotent K_C-orbit X in p_C and the L^2-inner product involves a K-Bessel function as density. Here K is a maximal compact subgroup of G, and g......_C=k_C+p_C is a complexified Cartan decomposition. In this realization the space of k-finite vectors consists of holomorphic polynomials on X. The reproducing kernel of the Fock space is calculated explicitly in terms of an I-Bessel function. We further find an explicit formula of a generalized Segal-Bargmann transform which...... intertwines the Schroedinger and Fock model. Its kernel involves the same I-Bessel function. Using the Segal--Bargmann transform we also determine the integral kernel of the unitary inversion operator in the Schroedinger model which is given by a J-Bessel function....

  3. q-deformed Minkowski space

    International Nuclear Information System (INIS)

    Ogievetsky, O.; Pillin, M.; Schmidke, W.B.; Wess, J.; Zumino, B.

    1993-01-01

    In this lecture I discuss the algebraic structure of a q-deformed four-vector space. It serves as a good example of quantizing Minkowski space. To give a physical interpretation of such a quantized Minkowski space we construct the Hilbert space representation and find that the relevant time and space operators have a discrete spectrum. Thus the q-deformed Minkowski space has a lattice structure. Nevertheless this lattice structure is compatible with the operation of q-deformed Lorentz transformations. The generators of the q-deformed Lorentz group can be represented as linear operators in the same Hilbert space. (orig.)

  4. The third spatial dimension risk approach for individual risk and group risk in multiple use of space

    International Nuclear Information System (INIS)

    Suddle, Shahid; Ale, Ben

    2005-01-01

    Buildings above roads and railways are examples of multiple use of space. Safety is one of the critical issues for such projects. Risk analyses can be undertaken to investigate what safety measures that are required to realise these projects. The results of these analyses can also be compared to risk acceptance criteria, if they are applicable. In The Netherlands, there are explicit criteria for acceptability of individual risk and societal risk. Traditionally calculations of individual risk result in contours of equal risk on a map and thus are considered in two-dimensional space only. However, when different functions are layered the third spatial dimension, height, becomes an important parameter. The various activities and structures above and below each other impose mutual risks. There are no explicit norms or policies about how to deal with the individual or group risk approach in the third dimension. This paper proposes an approach for these problems and gives some examples. Finally, the third dimension risk approach is applied in a case study of Bos en Lommer, Amsterdam

  5. Making media work in space: an interdisciplinary perspective on media and communication requirements for current and future space communities

    Science.gov (United States)

    Babidge, S.; Cokley, J.; Gordon, F.; Louw, E.

    2005-10-01

    As humans expand into space communities will form. These have already begun to form in small ways, such as long-duration missions on the International Space Station and the space shuttle, and small-scale tourist excursions into space. Social, behavioural and communications data emerging from such existing communities in space suggest that the physically-bounded, work-oriented and traditionally male-dominated nature of these extremely remote groups present specific problems for the resident astronauts, groups of them viewed as ‘communities’, and their associated groups who remain on Earth, including mission controllers, management and astronauts’ families. Notionally feminine group attributes such as adaptive competence, social adaptation skills and social sensitivity will be crucial to the viability of space communities and in the absence of gender equity, ‘staying in touch’ by means of ‘news from home’ becomes more important than ever. A template of news and media forms and technologies is suggested to service those needs and enhance the social viability of future terraforming activities.

  6. Computational derivation of quantum relativist electromagnetic systems with forward-backward space-time shifts

    International Nuclear Information System (INIS)

    Dubois, Daniel M.

    2000-01-01

    This paper is a continuation of our preceding paper dealing with computational derivation of the Klein-Gordon quantum relativist equation and the Schroedinger quantum equation with forward and backward space-time shifts. The first part introduces forward and backward derivatives for discrete and continuous systems. Generalized complex discrete and continuous derivatives are deduced. The second part deduces the Klein-Gordon equation from the space-time complex continuous derivatives. These derivatives take into account forward-backward space-time shifts related to an internal phase velocity u. The internal group velocity v is related to the speed of light u.v=c 2 and to the external group and phase velocities u.v=v g .v p . Without time shift, the Schroedinger equation is deduced, with a supplementary term, which could represent a reference potential. The third part deduces the Quantum Relativist Klein-Gordon equation for a particle in an electromagnetic field

  7. Group covariance and metrical theory

    International Nuclear Information System (INIS)

    Halpern, L.

    1983-01-01

    The a priori introduction of a Lie group of transformations into a physical theory has often proved to be useful; it usually serves to describe special simplified conditions before a general theory can be worked out. Newton's assumptions of absolute space and time are examples where the Euclidian group and translation group have been introduced. These groups were extended to the Galilei group and modified in the special theory of relativity to the Poincare group to describe physics under the given conditions covariantly in the simplest way. The criticism of the a priori character leads to the formulation of the general theory of relativity. The general metric theory does not really give preference to a particular invariance group - even the principle of equivalence can be adapted to a whole family of groups. The physical laws covariantly inserted into the metric space are however adapted to the Poincare group. 8 references

  8. The moduli space of instantons on an ALE space from 3d $\\mathcal{N}=4$ field theories

    CERN Document Server

    Mekareeya, Noppadol

    2015-01-01

    The moduli space of instantons on an ALE space is studied using the moduli space of $\\mathcal{N}=4$ field theories in three dimensions. For instantons in a simple gauge group $G$ on $\\mathbb{C}^2/\\mathbb{Z}_n$, the Hilbert series of such an instanton moduli space is computed from the Coulomb branch of the quiver given by the affine Dynkin diagram of $G$ with flavour nodes of unitary groups attached to various nodes of the Dynkin diagram. We provide a simple prescription to determine the ranks and the positions of these flavour nodes from the order of the orbifold $n$ and from the residual subgroup of $G$ that is left unbroken by the monodromy of the gauge field at infinity. For $G$ a simply laced group of type $A$, $D$ or $E$, the Higgs branch of such a quiver describes the moduli space of instantons in projective unitary group $PU(n) \\cong U(n)/U(1)$ on orbifold $\\mathbb{C}^2/\\hat{G}$, where $\\hat{G}$ is the discrete group that is in McKay correspondence to $G$. Moreover, we present the quiver whose Coulomb ...

  9. Space station propulsion requirements study

    Science.gov (United States)

    Wilkinson, C. L.; Brennan, S. M.

    1985-01-01

    Propulsion system requirements to support Low Earth Orbit (LEO) manned space station development and evolution over a wide range of potential capabilities and for a variety of STS servicing and space station operating strategies are described. The term space station and the overall space station configuration refers, for the purpose of this report, to a group of potential LEO spacecraft that support the overall space station mission. The group consisted of the central space station at 28.5 deg or 90 deg inclinations, unmanned free-flying spacecraft that are both tethered and untethered, a short-range servicing vehicle, and a longer range servicing vehicle capable of GEO payload transfer. The time phasing for preferred propulsion technology approaches is also investigated, as well as the high-leverage, state-of-the-art advancements needed, and the qualitative and quantitative benefits of these advancements on STS/space station operations. The time frame of propulsion technologies applicable to this study is the early 1990's to approximately the year 2000.

  10. One-dimensional zinc selenophosphates: A_2ZnP_2Se_6 (A = K, Rb, Cs)

    International Nuclear Information System (INIS)

    Haynes, Alyssa S.; Lee, Katherine; Kanatzidis, Mercouri G.

    2016-01-01

    The new compounds A_2ZnP_2Se_6 (A = K, Rb, Cs) were synthesized via molten salt flux syntheses. The crystals feature one-dimensional "1/_∞[ZnP_2Se_6]"2"- chains charge balanced by alkali metal ions between the chains. K_2ZnP_2Se_6 crystallizes in the monoclinic space group P2_1/c; cell parameters a = 12.537(3) Aa, b = 7.2742(14) Aa, c = 14.164(3) Aa, β = 109.63(3) , Z = 4, and V = 1216.7(4) Aa"3. Rb_2ZnP_2Se_6 and Cs_2ZnP_2Se_6 are isotypic, crystallizing in the triclinic space group P anti 1. Rb_2ZnP_2Se_6 has cell parameters of a = 7.4944(15) Aa, b = 7.6013(15) Aa, c = 12.729(3) Aa, α = 96.57(3) , β = 105.52(3) , γ = 110.54(3) , Z = 2, and V = 636.6(2) Aa"3. Cs_2ZnP_2Se_6 has cell parameters of a = 7.6543(6) Aa, b = 7.7006(6) Aa, c = 12.7373(11) Aa, α = 97.007(7) , β = 104.335(7) , γ = 109.241(6) , Z = 2, and V = 669.54(10) Aa"3. (Copyright copyright 2016 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  11. Density character of subgroups of topological groups

    OpenAIRE

    Leiderman, Arkady; Morris, Sidney A.; Tkachenko, Mikhail G.

    2015-01-01

    A subspace Y of a separable metrizable space X is separable, but without X metrizable this is not true even If Y is a closed linear subspace of a topological vector space X. K.H. Hofmann and S.A. Morris introduced the class of pro-Lie groups which consists of projective limits of finite-dimensional Lie groups and proved that it contains all compact groups, locally compact abelian groups and connected locally compact groups and is closed under products and closed subgroups. A topological group...

  12. New porphyrins bearing positively charged peripheral groups linked by a sulfonamide group to meso-tetraphenylporphyrin: interactions with calf thymus DNA.

    Science.gov (United States)

    Manono, Janet; Marzilli, Patricia A; Marzilli, Luigi G

    2009-07-06

    New water-soluble cationic meso-tetraarylporphyrins (TArP, Ar = 4-C(6)H(4)) and some metal derivatives have been synthesized and characterized. One main goal was to assess if N-methylpyridinium (N-Mepy) groups must be directly attached to the porphyrin core for intercalative binding of porphyrins to DNA. The new porphyrins have the general formula, [T(R(2)R(1)NSO(2)Ar)P]X(4/8) (R(1) = CH(3) or H and R(2) = N-Mepy-n-CH(2) with n = 2, 3, or 4; or R(1) = R(2) = Et(3)NCH(2)CH(2)). Interactions of selected porphyrins and metalloporphyrins (Cu(II), Zn(II)) with calf thymus DNA were investigated by visible circular dichroism (CD), absorption, and fluorescence spectroscopies. The DNA-induced changes in the porphyrin Soret region (a positive induced CD feature and, at high DNA concentration, increases in the Soret band and fluorescence intensities) indicate that the new porphyrins interact with DNA in an outside, non-self-stacking binding mode. Several new metalloporphyrins did not increase DNA solution viscosity and thus do not intercalate, confirming the conclusion drawn from spectroscopic studies. Porphyrins known to intercalate typically bear two or more N-Mepy groups directly attached to the porphyrin ring, such as the prototypical meso-tetra(N-Mepy)porphyrin tetracation (TMpyP(4)). The distances between the nitrogens of the N-Mepy group are estimated to be approximately 11 A (cis) and 16 A (trans) for the relatively rigid TMpyP(4). For the new flexible porphyrin, [T(N-Mepy-4-CH(2)(CH(3))NSO(2)Ar)P]Cl(4), the distances between the nitrogens are estimated to be able to span the range from approximately 9 to approximately 25 A. Thus, the N-Mepy groups in the new porphyrins can adopt the same spacing as in known intercalators such as TMpyP(4). The absence of intercalation by the new porphyrins indicates that the propensity for the N-Mepy group to facilitate DNA intercalation of cationic porphyrins requires direct attachment of N-Mepy groups to the porphyrin core.

  13. “Here is the knowledge-where should I put it?” Findings from a study of how knowledge spaces are used within a support group

    DEFF Research Database (Denmark)

    Carstensen, P. H.; Snis, U.

    1999-01-01

    In order to design useful knowledge media spaces for knowledge workers it is essential that we understand the nature of the work conducted and the knowledge applied in real settings. The paper reports from a study of how a group of quality assurance specialists in the pharmaceutical industry gather......, structure and distribute information and knowledge. Based on the findings, a number of overall requirements for knowledge media spaces are identified and discussed. The essential findings were that information and knowledge are created and handled in many different ways and have many different forms....... The core issues of our lessons learned so far are that we carefully need to consider knowledge media spaces both in terms of communication channels and knowledge archives. Knowledge media spaces should be seen as spaces in which knowledge and information is exchanged, filed, retrieved, presented...

  14. What's space to learning?

    DEFF Research Database (Denmark)

    Troelsen, Rie

    As “space […] works on its occupants” (Pouler cited in Scheer & Preiser 1994, p. 175), both students and teachers are influenced by the physical contexts in which learning occurs. However, so far focus on the furnishing of classrooms (and built environment as a whole) in universities as being of ...... and practices for technology supported physical learning spaces (JELS). Learning Sciences Research Institute at Nottingham University. Temple, P. (2008). Learning spaces in higher education: an under-researched topic. London Review of Education, 6(3), 229-41......As “space […] works on its occupants” (Pouler cited in Scheer & Preiser 1994, p. 175), both students and teachers are influenced by the physical contexts in which learning occurs. However, so far focus on the furnishing of classrooms (and built environment as a whole) in universities as being...... of importance to the student learning experience has not been overwhelming (Temple 2008). In this paper preliminary findings from a small-scale research project are presented aiming at investigating the influence of spatial conditions on teachers’ views on teaching and learning. Not to evaluate if any given...

  15. Trap assisted space charge conduction in p-NiO/n-ZnO heterojunction diode

    International Nuclear Information System (INIS)

    Tyagi, Manisha; Tomar, Monika; Gupta, Vinay

    2015-01-01

    Highlights: • p-NiO/n-ZnO heterojunction diode with enhanced junction parameters has been prepared. • Temperature dependent I–V throw insight into the involved conduction mechanism. • SCLC with exponential trap distribution was found to be the dominant mechanism. • C–V measurement at different frequencies support the presence of traps. - Abstract: The development of short-wavelength p–n junction is essentially important for the realization of transparent electronics for next-generation optoelectronic devices. In the present work, a p–n heterojunction diode based on p-NiO/n-ZnO has been prepared under the optimised growth conditions exhibiting improved electrical and junction parameters. The fabricated heterojunction gives typical current–voltage (I–V) characteristics with good rectifying behaviour (rectification ratio ≈ 10 4 at 2 V). The temperature dependent current–voltage characteristics of heterojunction diode have been studied and origin of conduction mechanism is identified. The space-charge limited conduction with exponential trap distribution having deep level trap is found to be the dominant conduction mechanism in the fabricated p–n heterojunction diode. The conduction and valence band discontinuities for NiO/ZnO heterostructure have been determined from the capacitance–voltage (C–V) measurements

  16. Management of Pleural Space After Lung Resection by Cryoneuroablation of Phrenic Nerve: A Randomized Study.

    Science.gov (United States)

    Pan, Xiao-Jie; Ou, De-Bin; Lin, Xing; Ye, Ming-Fang

    2017-06-01

    Residual air space problems after pulmonary lobectomy are an important concern in thoracic surgical practice, and various procedures have been applied to manage them. This study describes a novel technique using controllable paralysis of the diaphragm by localized freezing of the phrenic nerve, and assesses the effectiveness of this procedure to reduce air space after pulmonary lobectomy. In this prospective randomized study, 207 patients who underwent lobectomy or bilobectomy and systematic mediastinal node dissection in our department between January 2009 and November 2013 were randomly allocated to a cryoneuroablation group or a conventional group. Patients in the cryoneuroablation group (n = 104) received phrenic nerve cryoneuroablation after lung procedures, and patients in the conventional group (n = 103) did not receive cryoneuroablation after the procedure. Data regarding preoperative clinical and surgical characteristics in both groups were collected. Both groups were compared with regard to postoperative parameters such as total amount of pleural drainage, duration of chest tube placement, length of hospital stay, requirement for repeat chest drain insertion, prolonged air leak, and residual space. Perioperative lung function was also compared in both groups. Recovery of diaphragmatic movement in the cryoneuroablation group was checked by fluoroscopy on the 15th, 30th, and 60th day after surgery. There was no statistically significant difference in patient characteristics between the 2 groups; nor was there a difference in terms of hospital stay, new drain requirement, and incidence of empyema. In comparison with the conventional group, the cryoneuroablation group had less total drainage (1024 ± 562 vs 1520 ± 631 mL, P phrenic nerve offers a reasonable option for prevention of residual air space following major pulmonary resection.

  17. On functional bases of the first-order differential invariants for non-conjugate subgroups of the Poincaré group $P(1,4$

    Directory of Open Access Journals (Sweden)

    V.M. Fedorchuk

    2008-11-01

    Full Text Available It is established which functional bases of the first-order differential invariants of the splitting and non-splitting subgroups of the Poincaré group $P(1,4$ are invariant under the subgroups of the extended Galilei group $widetilde G(1,3 subset P(1,4$. The obtained sets of functional bases are classified according to dimensions.

  18. Symmetry-adapted Liouville space. Pt. 7

    International Nuclear Information System (INIS)

    Temme, F.P.

    1990-01-01

    In examining nuclear spin dynamics of NMR spin clusters in density operator/generalized torque formalisms over vertical strokekqv>> operator bases of Liouville space, it is necessary to consider the symmetry mappings and carrier spaces under a specialized group for such (k i = 1) nuclear spin clusters. The SU2 X S n group provides the essential mappings and the form of H carrier space, which allows one to: (a) draw comparisons with Hilbert space duality, and (b) outline the form of the Coleman-Kotani genealogical hierarchy under induced S n -symmetry. (orig.)

  19. Competing for space in an already crowded market: a mixed methods study of why an online community of practice (CoP) for alcohol harm reduction failed to generate interest amongst the group of public health professionals at which it was aimed.

    Science.gov (United States)

    Ponsford, Ruth; Ford, Jennifer; Korjonen, Helena; Hughes, Emma; Keswani, Asha; Pliakas, Triantafyllos; Egan, Matt

    2017-07-21

    Improving mechanisms for knowledge translation (KT) and connecting decision-makers to each other and the information and evidence they consider relevant to their work remains a priority for public health. Virtual communities of practices (CoPs) potentially offer an affordable and flexible means of encouraging connection and sharing of evidence, information and learning among the public health community in ways that transgress traditional geographical, professional, institutional and time boundaries. The suitability of online CoPs in public health, however, has rarely been tested. This paper explores the reasons why particular online CoP for alcohol harm reduction hosted by the UK Health Forum failed to generate sufficient interest from the group of public health professionals at which it was aimed. The study utilises online web-metrics demonstrating a lack of online activity on the CoP. One hundred and twenty seven responses to an online questionnaire were used to explore whether the lack of activity could be explained by the target audience's existing information and evidence practices and needs. Qualitative interviews with 10 members describe in more detail the factors that shape and inhibit use of the virtual CoP by those at which it was targeted. Quantitative and qualitative data confirm that the target audience had an interest in the kind of information and evidence the CoP was set up to share and generate discussion about, but also that participants considered themselves to already have relatively good access to the information and evidence they needed to inform their work. Qualitative data revealed that the main barriers to using the CoP were a proliferation of information sources meaning that participants preferred to utilise trusted sources that were already established within their daily routines and a lack of time to engage with new online tools that required any significant commitment. Specialist online CoPs are competing for space in an already crowded

  20. Critical Dynamics of the Xy-Model on the One-Dimensional Superlattice by Position Space Renormalization Group

    Science.gov (United States)

    Lima, J. P. De; Gonçalves, L. L.

    The critical dynamics of the isotropic XY-model on the one-dimensional superlattice is considered in the framework of the position space renormalization group theory. The decimation transformation is introduced by considering the equations of motion of the operators associated to the excitations of the system, and it corresponds to an extension of the procedure introduced by Stinchcombe and dos Santos (J. Phys. A18, L597 (1985)) for the homogeneous lattice. The dispersion relation is obtained exactly and the static and dynamic scaling forms are explicitly determined. The dynamic critical exponent is also obtained and it is shown that it is identical to the one of the XY-model on the homogeneous chain.

  1. [Clinical evaluation of the postburn retention and the metabolism of Imipenem in the third space].

    Science.gov (United States)

    Rong, Xin-Zhou; Bei, Chun-Hua; Huang, Xiao-Hua; Li, Qing-Hui

    2003-04-01

    To explore the half life and retention of Imipenem in the third space. Eight severely burned patients and eight healthy volunteers were enrolled as the burn group (B) and normal control group (C), respectively. HPLC (high performance liquid chromatography) was employed to determine the contents of Imipenem in the plasma, subeschar tissue fluid (STF) and the changes in its pharmacokinetics. Furthermore, the Imipenem content in the third space was calculated according to the systemic edema degree. The half life of Imipenem in STF (2.53 h) was longer than that in plasma (1.73 h), P < 0.05). The Imipenem content in STF increased gradually along with the lapse of time after repeated intravenous infusion of Imipenem, and at the same the total content of imipenem was increased significantly in the third space. There was antibiotic retention in the third space after severe burn injury, and a prolonged action of the drug could be expected when the drug re-entered the blood stream.

  2. "Con Café, Compañerismo, y Calidad": Latina Women Fashioning a Writing Group into a Space of Praxis and Belonging

    Science.gov (United States)

    Hurtig, Janise

    2016-01-01

    This article explores the spatial practices through which a group of Mexican immigrant women, participants in a school-based writing workshop I facilitated for four years, molded and gave meaning to our weekly writing routine to foster inclusivity as the basis for collective teaching and learning--creating what I refer to as a space of praxis and…

  3. Interdigital Melanoma of the Foot Affecting Two Neighbouring Interdigital Spaces – Second Case Report

    Directory of Open Access Journals (Sweden)

    Uwe Wollina

    2017-07-01

    Full Text Available Melanoma affecting two interdigital spaces has been recently described by our group for the first time in medical literature. Here we present a second patient with acrolentiginous melanoma of the sole affecting the 1st and 2nd interdigital space. The tumour was removed by delayed Mohs surgery. Due to the extension of the melanoma, digit II and III had to be removed. Staging excluded metastatic spread. The tumour was classified as pT4bN0M0.

  4. Fibonacci difference sequence spaces for modulus functions

    Directory of Open Access Journals (Sweden)

    Kuldip Raj

    2015-05-01

    Full Text Available In the present paper we introduce Fibonacci difference sequence spaces l(F, Ƒ, p, u and  l_∞(F, Ƒ, p, u by using a sequence of modulus functions and a new band matrix F. We also make an effort to study some inclusion relations, topological and geometric properties of these spaces. Furthermore, the alpha, beta, gamma duals and matrix transformation of the space l(F, Ƒ, p, u are determined.

  5. Effect of space allowance during transport and fasting or non-fasting during lairage on welfare indicators in Merino lambs

    Energy Technology Data Exchange (ETDEWEB)

    Cozar, A.; Rodriguez, A.I.; Garijo, P.; Calvo, L.; Vergara, H.

    2016-11-01

    A total of 72 male lambs of Merina breed were sampled in a 3×2 factorial design, testing three different space allowances treatment (SA) during transport [0.16 m2/animal (SAL; n=24); 0.20 m2/animal (SAM; n=24) and 0.30 m2/animal (SAH; n=24)] and two lairage treatments (TL) during 18 h previous slaughter [fasting (FAST; n=36) vs feeding (FEED; n=36)] on welfare physiological indicators. After transport, glucose and lactate dehydrogenase (LDH) were highest in SAM group and lowest in SAH one (p<0.05). SAL showed intermediate values for both parameters. SA did not affect the rest of the blood parameters studied. TL-FAST treatment decreased glucose values (p<0.001) while increased LDH (p<0.001). Fasting caused an increase (p<0.05) of Red Blood Cell Count values in SAM group. Feed deprivation did not affect cortisol or adrenaline values. Noradrenaline value was higher (p<0.001) in TL-FAST groups than in TL-FEED. In conclusion, under the conditions of this study, a range of space allowance during transport between 0.16 and 0.30 m2/lamb could be recommended without showing major changes on welfare physiological indicators; and feeding could be more appropriate than fasting during lairage. (Author)

  6. Onset and Effect Duration of Intrabuccal Space and Intramuscular Ketamine in Pediatrics

    Directory of Open Access Journals (Sweden)

    Saeed Majidi

    2018-01-01

    Full Text Available Background: Painful diagnostic and therapeutic procedures performed for children are routine actions. Opioids and nonsteroidal anti-inflammatory drugs such as acetaminophens are among medications that can be used for this purpose. This study aimed to compare the onset and duration of action of intrabuccal (IB, submucosal space and intramuscular (IM injection of ketamine in pediatrics. Materials and Methods: This clinical trial study was carried out on 126 children of 1–15 years old referred to the emergency room of Al-Zahra and Kashani Hospitals in Isfahan and divided into two 63 populated groups of IM and IB. For one group randomly, 3 mg/kg IB ketamine was administered, and for another group, ketamine was injected intramuscularly at the dose of 5 mg/kg. The drug effect, surgeon satisfaction, and complications were evaluated. Data were analyzed using SPSS software. Results: The mean of time between injection and onset of drug effect in IM group was 5.71 min, whereas in IB group, it was 4.14 min (P < 0.0001. The mean of the duration of drug effect in IM group was 45.54 min, whereas in IB group, it was 24.63 min (P < 0.0001. Complications in IM group were significantly more reported than IB group (33.3% versus 11.1%, respectively, P = 003. The median of surgeon satisfaction in IM group was 3 and in IB group was 4 which was statistically significant (P = 0.007. Conclusions: IB method is preferred over IM method, and hence, it is recommended to use.

  7. Synthesis of the semi-organic nonlinear optical crystal l-glutamic acid zinc chloride and investigation of its growth and physiochemical properties

    Directory of Open Access Journals (Sweden)

    S. Chennakrishnan

    2017-11-01

    Full Text Available The aim of this study is to synthesize and investigate the growth and physiochemical properties of the nonlinear optical semi-organic crystal l-glutamic acid zinc chloride (LGAZC. An optically transparent and defect-free crystal was grown with the slow evaporation solution growth technique under optimized conditions. The induction periods were measured at various supersaturations, and the interfacial energies were evaluated. Single crystal X-ray diffraction reveals that the crystal has an orthorhombic structure with space group P212121, and the calculated lattice parameters are a = 5.20 Å, b = 6.99 Å, c = 17.58 Å, α = β = γ = 90° and volume = 623.411 Å3. Spectroscopic properties were investigated by recording the Fourier transform infrared and optical transmission spectra. The thermal decomposition of the grown crystal was investigated by Thermo Gravimetric and Differential Thermal Analysis (TG/DTA. The LGAZC crystal exhibits second harmonic generation (SHG efficiency 1.5 times that of inorganic KDP crystal. The presence of the metal ion (Zn+ in a grown crystal was identified by EDAX spectrum analysis. The photoconductivity study demonstrates that LGAZC crystal has a positive photo conducting nature. The dielectric response of the LGAZC crystal was investigated and reported. Keywords: Semi-organic nonlinear optical crystal, X-ray Diffraction, UV-vis-NIR, Thermal study

  8. Space Station Workshop: Commercial Missions and User Requirements

    Science.gov (United States)

    1988-01-01

    The topics of discussion addressed during a three day workshop on commercial application in space are presented. Approximately half of the program was directed towards an overview and orientation to the Space Station Project; the technical attributes of space; and present and future potential commercial opportunities. The remaining time was spent addressing technological issues presented by previously-formed industry working groups, who attempted to identify the technology needs, problems or issues faced and/or anticipated by the following industries: extraction (mining, agriculture, petroleum, fishing, etc.); fabrication (manufacturing, automotive, aircraft, chemical, pharmaceutical and electronics); and services (communications, transportation and retail robotics). After the industry groups presented their technology issues, the workshop divided into smaller discussion groups composed of: space experts from NASA; academia; industry experts in the appropriate disciplines; and other workshop participants. The needs identified by the industry working groups, space station technical requirements, proposed commercial ventures and other issues related to space commercialization were discussed. The material summarized and reported are the consensus from the discussion groups.

  9. [Factors related to the life space of daycare center users].

    Science.gov (United States)

    Kawamura, Koki; Kato, Chikako; Kondo, Izumi

    2018-01-01

    We examined the factors related to life space and changes in the care level after one year in daycare center users. The participants were 83 older adults (age, > 65 years; mean age, 79.5±6.8 years) with MMSE scores of ≥20, who could walk independently, who needed support (1-2) or care (1), and who underwent rehabilitation at a daycare center. The life space was evaluated by the Life Space Assessment (LSA). The subjects' basic information (i.e., age, medical history.) was collected, and their physical function (i.e., grip strength, timed up and go test [TUG]), mental function (i.e., vitality, fear of falls), and social function (i.e., friends, hobbies, public transportation) were assessed to investigate the factors associated with their LSA scores. In addition, a follow-up survey was conducted on the care level at approximately one year later. A multiple regression analysis indicated that TUG scores (β=-0.33), hobbies (β=0.30), friends (β=0.29), public transportation (β=0.26), and grip strength (β=0.24) were related to the life space. Next, the participants were divided into LSA-high and LSA-low groups, and changes in the care level (improvement, maintenance, deterioration) at approximately one year after the initial assessment were examined using a chi-squared test. A significant difference was observed in the distribution of the groups (p=0.03). Multiple factors were related to the life space. Moreover, it is possible that improvements in the level of care may be achieved by improving the life space.

  10. Generalizations of the BMS group and results

    International Nuclear Information System (INIS)

    Melas, E

    2006-01-01

    The ordinary Bondi-Metzner-Sachs (BMS) group B is the common asymptotic symmetry group of all radiating, asymptotically flat, Lorentzian space-times. As such, B is the best candidate for the universal symmetry group of General Relativity. However, in studying quantum gravity, space-times with signatures other than the usual Lorentzian one, and complex space-times, are frequently considered. Generalisations of B appropriate to these other signatures have been defined earlier. In particular, the generalization B(2, 2) appropriate to the ultrahyperbolic signature (+, +, -, -) has been described in detail, and the study of its irreducible unitary representations (IRs) has been initiated. The infinite little groups of B(2, 2) have been given explicitly but its finite little groups have only been partially described. All the information needed in order to construct the finite little groups is given. Possible connections with gravitational instantons are being put forward

  11. Space dependent neutron slowing and thermalization in monatomic hydrogen gas in the P-1 approximation

    International Nuclear Information System (INIS)

    Musazay, M.S.

    1981-01-01

    A solution to the space and energy dependent neutron transport equation in the framework of the consistent P-1 approximation is sought. The transport equation for thermal neutrons in a moderator of 1/v absorption and constant scattering cross section is changed into a set of coupled partial differential equations. The space dependent part is removed by assuming a cosine shaped flux due to a cosine shaped source at a very high energy. The resulting set of strongly coupled ordinary differential equations is decoupled by assuming expansion of collision density in the powers of a leakage parameter whose coefficients are energy and absorption dependent. These energy dependent coefficients are solutions of a set of weakly coupled differential equations. Series solutions to these differential equations in powers of epsilon and 1/epsilon, where epsilon = E/kT, E being the neutron energy and kT the moderator temperature in units of energy, are found. The properties of these solutions are studied extensively. Absorption appears as a parameter in the coefficients of the series. The difficulties arising in choosing the correct form of the asymptotic solutions are resolved by comparing slowing and thermalization. The limitations on the size of the slab and on the range of absorption are included in the analysis

  12. A Space Apart

    Directory of Open Access Journals (Sweden)

    Lisa Lynch

    2017-01-01

    Full Text Available This article examines how the preschool child is enabled to withdraw from the peer group and create a private, individual space within the institutional collective. The question under consideration is, “What factors are necessary to enable a child to create and maintain a withdrawal space in the preschool?” Data were collected through ethnographic fieldwork at two Montessori schools in the south of Sweden. Analysis of the results reveals that a child is enabled through a combination of two elements: a level of opportunity to create a space and a level of defense of a created space. These two factors are dependent on the teachers’ ability to correctly identify space creation, alongside their desire for the child’s space creation effort to be successful.

  13. [Effect of axial stress stimulation on tibial and fibular open fractures healing after Taylor space stent fixation].

    Science.gov (United States)

    Ge, Qihang; Wan, Chunyou; Liu, Yabei; Ji, Xu; Ma, Jihai; Cao, Haikun; Yong, Wei; Liu, Zhao; Zhang, Ningning

    2017-08-01

    To investigate the effect of axial stress stimulation on tibial and fibular open fractures healing after Taylor space stent fixation. The data of 45 cases with tibial and fibular open fractures treated by Taylor space stent fixation who meet the selection criteria between January 2015 and June 2016 were retrospectively analysed. The patients were divided into trial group (23 cases) and control group (22 cases) according to whether the axial stress stimulation was performed after operation. There was no significant difference in gender, age, affected side, cause of injury, type of fracture, and interval time from injury to operation between 2 groups ( P >0.05). The axial stress stimulation was performed in trial group after operation. The axial load sharing ratio was tested, and when the value was less than 10%, the external fixator was removed. The fracture healing time, full weight-bearing time, and external fixator removal time were recorded and compared. After 6 months of external fixator removal, the function of the limb was assessed by Johner-Wruhs criteria for evaluation of final effectiveness of treatment of tibial shaft fractures. There were 2 and 3 cases of needle foreign body reaction in trial group and control group, respectively, and healed after symptomatic anti allergic treatment. All the patients were followed up 8-12 months with an average of 10 months. All the fractures reached clinical healing, no complication such as delayed union, nonunion, or osteomyelitis occurred. The fracture healing time, full weight-bearing time, and external fixator removal time in trial group were significantly shorter than those in control group ( P good in 6 cases, fair in 3 cases, and poor in 1 case in trial group, with an excellent and good rate of 82.6%; and was excellent in 5 cases, good in 10 cases, fair in 4 cases, and poor in 3 cases in control group, with an excellent and good rate of 68.2%, showing significant difference between 2 groups ( Z =-2.146, P =0

  14. Invariant subsets under compact quantum group actions

    OpenAIRE

    Huang, Huichi

    2012-01-01

    We investigate compact quantum group actions on unital $C^*$-algebras by analyzing invariant subsets and invariant states. In particular, we come up with the concept of compact quantum group orbits and use it to show that countable compact metrizable spaces with infinitely many points are not quantum homogeneous spaces.

  15. Space dynamics

    International Nuclear Information System (INIS)

    Corno, S.E.

    1995-01-01

    Analytical methods for Space Dynamics of fission reactors, are presented. It is shown how a few sample problems in space dynamics can be solved, within the one and two group diffusion model, by purely analytical tools, essentially based on Laplace transform and complex Green function techniques. A quite suggestive generalization of this approach, applicable to the fluid core reactors, whose fuel is undergoing a violent mixing, is reported and briefly discussed. (author)

  16. Consciousness viewed in the framework of brain phase space dynamics, criticality, and the Renormalization Group

    International Nuclear Information System (INIS)

    Werner, Gerhard

    2013-01-01

    The topic of this paper will be addressed in three stages: I will first review currently prominent theoretical conceptualizations of the neurobiology of consciousness and, where appropriate, identify ill-advised and flawed notions in theoretical neuroscience that may impede viewing consciousness as a phenomenon in the physics of brain. In this context, I will also introduce relevant facts that tend not to receive adequate attention in much of the current consciousness discourse. Next, I will review the evidence that accrued in the last decade that identifies the resting brain as being in a state of criticality. In the framework of state phase dynamics of statistical physics, this observational evidence also entails that the resting brain is poised at the brink of a second order phase transition. On this basis, I will in the third stage propose applying the framework of the Renormalization Group to viewing consciousness as a phenomenon in statistical physics. In physics, concepts of phase space transitions and the Renormalization Group are powerful tools for interpreting phenomena involving many scales of length and time in complex systems. The significance of these concepts lies in their accounting for the emergence of different levels of new collective behaviors in complex systems, each level with its distinct macroscopic physics, organization, and laws, as a new pattern of reality. In this framework, I propose to view subjectivity as the symbolic description of the physical brain state of consciousness that emerges as one of the levels of phase transitions of the brain-body-environment system, along the trajectory of Renormalization Group Transformations

  17. Space loss following premature loss of primary second molars.

    Science.gov (United States)

    Alnahwi, Hassan H; Donly, Kevin J; Contreras, Claudia I

    2015-01-01

    This study was designed to evaluate the amount of space loss (SL) caused by premature loss of primary second molars, determine whether the eruption status of permanent first molars is an important factor in the amount of SL, and evaluate the effectiveness of space maintainers (SMs) in SL prevention. SL associated with 100 prematurely extracted primary second molars was evaluated in 87 healthy patients. Teeth were divided into groups based on the use of SMs (36 with SM and 64 without SM). Bitewing and periapical radiographs taken before extraction and 6, 12, 24, 36, and 48 months after extraction were used to determine the amount of SL. Not every patient attended every recall appointment, so the sample size varied at different evaluation times. The most significant amount of SL occurred in the first 12 months after extraction. In patients who did not use an SM, at 6 months there was a mean SL of 2.12 mm (SD, 1.65 mm) and at 12 months there was a mean of 4.02 mm (SD, 1.65), with significantly more SL in the first 6 months (P 0.05). When patients without an SM were grouped by the eruption status of the permanent first molar, there was significantly more SL in the groups with unerupted first molars than there was in the groups with erupted first molars at both 6 months (P < 0.001) and 12 months (P < 0.05). At both 6 and 12 months, the amount of SL in patients who had an SM (n = 13 and n = 14, respectively) was not significantly different from the amount of SL in those who did not have an SM (n = 33 and n = 23, respectively). SMs should be placed as soon as possible following tooth extraction to prevent undue SL. Placement of an SM a year or more after extraction has minimal benefit, since most SL takes place within the first year. SL does occur even when SMs are used.

  18. Integrating cell-free biosyntheses of heme prosthetic group and apoenzyme for the synthesis of functional P450 monooxygenase.

    Science.gov (United States)

    Kwon, Yong-Chan; Oh, In-Seok; Lee, Nahum; Lee, Kyung-Ho; Yoon, Yeo Joon; Lee, Eun Yeol; Kim, Byung-Gee; Kim, Dong-Myung

    2013-04-01

    Harnessing the isolated protein synthesis machinery, cell-free protein synthesis reproduces the cellular process of decoding genetic information in artificially controlled environments. More often than not, however, generation of functional proteins requires more than simple translation of genetic sequences. For instance, many of the industrially important enzymes require non-protein prosthetic groups for biological activity. Herein, we report the complete cell-free biogenesis of a heme prosthetic group and its integration with concurrent apoenzyme synthesis for the production of functional P450 monooxygenase. Step reactions required for the syntheses of apoenzyme and the prosthetic group have been designed so that these two separate pathways take place in the same reaction mixture, being insulated from each other. Combined pathways for the synthesis of functional P450 monooxygenase were then further integrated with in situ assay reactions to enable real-time measurement of enzymatic activity during its synthesis. Copyright © 2012 Wiley Periodicals, Inc.

  19. Responding to the Concerns of Student Cultural Groups: Redesigning Spaces for Cultural Centers

    Science.gov (United States)

    McDowell, Anise Mazone; Higbee, Jeanne L.

    2014-01-01

    This paper describes the engagement of a student committee in redesigning an entire floor of a university union to accommodate student cultural centers and provide space in a fair and equitable manner. The reorganization focused on the process as well as the task of allocating space, with an emphasis on the opportunity to foster the development of…

  20. Upper Incisor Changes Due to Modifying the Point of Application of Forces during Space Closure in MBT Technique

    Directory of Open Access Journals (Sweden)

    H. Ravanmehr

    2004-06-01

    Full Text Available Statement of Problem: A recent technique (MBT has been introduced for easy and efficient orthodontic treatment by means of straight wire fixed appliances. Although this technique has many advantages, in space closure stage causes up righting problem in upper incisors, which should be adjusted by applying additional torque in anterior region.Purpose: The purpose of this clinical trial was to determine whether there is a significant difference in final incisor inclination (torque of two groups one treated with MBT technique and the other by changing the point of application of the closing force (in anterior region.Materials and Methods: Twelve patients (8 girls, 4 boys with Cl I malocclusion and crowding, whom were candidate for first premolars extraction, were selected.For space closure, 6 anterior teeth (canine to canine in upper and lower jaws ligated and the applied force was from the hooks on canines to hooks on the first molars.After space closure the results compared with the results of a previous study which treatment plan was according to original MBT technique (anterior hooks soldered to arch wire. Forces applied randomly among quadrants by NiTi coil spring (American Orthodontics Co. or active tie backs with elastic modules (Dentaurum Co.Results: The results showed a statistically significant difference between final torques of two techniques (P=0.0001. Also, the rate of space closure with NiTi coils was significantly greater than active tie back (P=0.0001.Conclusion: Anchorage loss in two groups compared and the results indicated significantly lower anchorage loss in NiTi coil spring group (P=0.035.

  1. Everyday spaces of inter-ethnic interaction: the meaning of urban public spaces in the Netherlands

    NARCIS (Netherlands)

    Peters, K.B.M.; Haan, de H.J.

    2011-01-01

    Ethnic diversity is manifest in public spaces by the presence of people originating from all over the world. It is also manifest in typical ethnic spaces that are predominantly used by specific ethnic groups. This article focuses on how people from various ethnic backgrounds use urban public spaces

  2. Homology groups for particles on one-connected graphs

    Science.gov (United States)

    MaciÄ Żek, Tomasz; Sawicki, Adam

    2017-06-01

    We present a mathematical framework for describing the topology of configuration spaces for particles on one-connected graphs. In particular, we compute the homology groups over integers for different classes of one-connected graphs. Our approach is based on some fundamental combinatorial properties of the configuration spaces, Mayer-Vietoris sequences for different parts of configuration spaces, and some limited use of discrete Morse theory. As one of the results, we derive the closed-form formulae for ranks of the homology groups for indistinguishable particles on tree graphs. We also give a detailed discussion of the second homology group of the configuration space of both distinguishable and indistinguishable particles. Our motivation is the search for new kinds of quantum statistics.

  3. Space Station Habitability Research

    Science.gov (United States)

    Clearwater, Yvonne A.

    1988-01-01

    The purpose and scope of the Habitability Research Group within the Space Human Factors Office at the NASA/Ames Research Center is described. Both near-term and long-term research objectives in the space human factors program pertaining to the U.S. manned Space Station are introduced. The concept of habitability and its relevancy to the U.S. space program is defined within a historical context. The relationship of habitability research to the optimization of environmental and operational determinants of productivity is discussed. Ongoing habitability research efforts pertaining to living and working on the Space Station are described.

  4. Trap assisted space charge conduction in p-NiO/n-ZnO heterojunction diode

    Energy Technology Data Exchange (ETDEWEB)

    Tyagi, Manisha [Department of Physics and Astrophysics, University of Delhi, Delhi-110007 (India); Tomar, Monika [Physics department, Miranda House, University of Delhi, Delhi-110007 (India); Gupta, Vinay, E-mail: drguptavinay@gmail.com [Department of Physics and Astrophysics, University of Delhi, Delhi-110007 (India)

    2015-06-15

    Highlights: • p-NiO/n-ZnO heterojunction diode with enhanced junction parameters has been prepared. • Temperature dependent I–V throw insight into the involved conduction mechanism. • SCLC with exponential trap distribution was found to be the dominant mechanism. • C–V measurement at different frequencies support the presence of traps. - Abstract: The development of short-wavelength p–n junction is essentially important for the realization of transparent electronics for next-generation optoelectronic devices. In the present work, a p–n heterojunction diode based on p-NiO/n-ZnO has been prepared under the optimised growth conditions exhibiting improved electrical and junction parameters. The fabricated heterojunction gives typical current–voltage (I–V) characteristics with good rectifying behaviour (rectification ratio ≈ 10{sup 4} at 2 V). The temperature dependent current–voltage characteristics of heterojunction diode have been studied and origin of conduction mechanism is identified. The space-charge limited conduction with exponential trap distribution having deep level trap is found to be the dominant conduction mechanism in the fabricated p–n heterojunction diode. The conduction and valence band discontinuities for NiO/ZnO heterostructure have been determined from the capacitance–voltage (C–V) measurements.

  5. Topological transformation groups and Dugundji compacta

    International Nuclear Information System (INIS)

    Kozlov, Konstantin L; Chatyrko, Vitalii A

    2010-01-01

    The presence of an algebraic structure on a space, which is compatible with its topology, in many cases imposes very strong restrictions on the properties of the space itself. Conditions are found which must be satisfied by the actions in order for the phase space to be a d-space (Dugundji compactum). This investigation allows the range of G-spaces that are d-spaces (Dugundji compacta) to be substantially widened. It is shown that all the cases known to the authors where a G-space (a topological group, one of its quotient spaces) is a d-space can be realized using equivariant maps. Bibliography: 39 titles.

  6. Spaces of homotopy self-equivalences a survey

    CERN Document Server

    Rutter, John W

    1997-01-01

    This survey covers groups of homotopy self-equivalence classes of topological spaces, and the homotopy type of spaces of homotopy self-equivalences. For manifolds, the full group of equivalences and the mapping class group are compared, as are the corresponding spaces. Included are methods of calculation, numerous calculations, finite generation results, Whitehead torsion and other areas. Some 330 references are given. The book assumes familiarity with cell complexes, homology and homotopy. Graduate students and established researchers can use it for learning, for reference, and to determine the current state of knowledge.

  7. Space Biology and Medicine. Volume 4; Health, Performance, and Safety of Space Crews

    Science.gov (United States)

    Dietlein, Lawrence F. (Editor); Pestov, Igor D. (Editor)

    2004-01-01

    Volume IV is devoted to examining the medical and associated organizational measures used to maintain the health of space crews and to support their performance before, during, and after space flight. These measures, collectively known as the medical flight support system, are important contributors to the safety and success of space flight. The contributions of space hardware and the spacecraft environment to flight safety and mission success are covered in previous volumes of the Space Biology and Medicine series. In Volume IV, we address means of improving the reliability of people who are required to function in the unfamiliar environment of space flight as well as the importance of those who support the crew. Please note that the extensive collaboration between Russian and American teams for this volume of work resulted in a timeframe of publication longer than originally anticipated. Therefore, new research or insights may have emerged since the authors composed their chapters and references. This volume includes a list of authors' names and addresses should readers seek specifics on new information. At least three groups of factors act to perturb human physiological homeostasis during space flight. All have significant influence on health, psychological, and emotional status, tolerance, and work capacity. The first and most important of these factors is weightlessness, the most specific and radical change in the ambient environment; it causes a variety of functional and structural changes in human physiology. The second group of factors precludes the constraints associated with living in the sealed, confined environment of spacecraft. Although these factors are not unique to space flight, the limitations they entail in terms of an uncomfortable environment can diminish the well-being and performance of crewmembers in space. The third group of factors includes the occupational and social factors associated with the difficult, critical nature of the

  8. Normal edge-transitive and $ frac{1}{2}$-arc-transitive Cayley graphs on non-abelian groups of order $2pq$ , $p > q$ are primes

    Directory of Open Access Journals (Sweden)

    Ali Reza Ashrafi

    2016-09-01

    Full Text Available Darafsheh and Assari in [Normal edge-transitive Cayley graphs onnon-abelian groups of order 4p, where p is a prime number,Sci. China Math. {bf 56} (1 (2013 213$-$219.] classified the connected normal edge transitive and$frac{1}{2}-$arc-transitive Cayley graph of groups of order$4p$. In this paper we continue this work by classifying theconnected Cayley graph of groups of order $2pq$, $p > q$ areprimes. As a consequence it is proved that $Cay(G,S$ is a$frac{1}{2}-$edge-transitive Cayley graph of order $2pq$, $p> q$ if and only if $|S|$ is an even integer greater than 2, $S =T cup T^{-1}$ and $T subseteq { cba^{i} | 0 leq i leq p- 1}$ such that $T$ and $T^{-1}$ are orbits of $Aut(G,S$ andbegin{eqnarray*}G &=& langle a, b, c | a^p = b^q = c^2 = e, ac = ca, bc = cb, b^{-1}ab = a^r rangle,G &=& langle a, b, c | a^p = b^q = c^2 = e, c ac = a^{-1}, bc = cb, b^{-1}ab = a^r rangle,end{eqnarray*}where $r^q equiv 1 (mod p$.

  9. Synthesis, structural characterization, and thermal stability studies of heteroleptic cadmium(II) dithiocarbamate with different pyridyl groups

    Science.gov (United States)

    Onwudiwe, Damian C.; Hosten, Eric C.

    2018-01-01

    The synthesis, characterization and crystal structures of three chloroform solvated adducts of cadmium with mixed ligands of N-alkyl-N-phenyldithiocarbamate and pyridine, 2,2-bipyridine and 1, 10 phenanthroline represented as [CdL1L2 (py)2]·CHCl3(1), [CdL1L2bpy]•CHCl3(2), and [CdL1L2phen]•CHCl3(3) (LI = N-methyl-N-phenyldithiocarbamate, L2 = N-ethyl-N-phenyldithiocarbamate, py = pyridine, bpy = 2,2-bipyridine and phen = 1,10-phenanthroline) respectively are reported. Complex 1, which crystallized in the monoclinic space group P-1, is a centrosymmetric dimeric structure where each Cd center is bonded to two monodentate pyridine, a bidentate terminal dithiocarbamate, and another bidentate bridging dithiocarbamate to form a four-membered ring. Complex 2 crystallized in the monoclinic space group P21/c, with four discrete monomeric molecules in the asymmetric unit. The structure presents a cadmium atom coordinated by two sulphur atoms of a dithiocarbamate ligand and two nitrogen atoms of the 2,2‧-bipyridine to form a CdS4N2 fragment, thus giving the structure around the Cd atom a distorted trigonal prism geometry. Complex 3 contains two discrete monomeric molecules of (phenanthroline) (N, N-methyl phenyl-N, N-ethyl phenyl dithiocarbamato)cadmium (II) per unit cell, and the complex crystallized in the triclinic space group P-1. The structure showed that the Cd atom is bonded to two bidentate dithiocarbamate ligands and to one bidentate phenanthroline ligand in a distorted trigonal prism geometry. All the compounds resulted in CdS as residue upon thermal decomposition process conducted under inert atmosphere.

  10. Riesz basis for strongly continuous groups.

    NARCIS (Netherlands)

    Zwart, Heiko J.

    Given a Hilbert space and the generator of a strongly continuous group on this Hilbert space. If the eigenvalues of the generator have a uniform gap, and if the span of the corresponding eigenvectors is dense, then these eigenvectors form a Riesz basis (or unconditional basis) of the Hilbert space.

  11. ′Metal to resin′: A comparative evaluation of conventional band and loop space maintainer with the fiber reinforced composite resin space maintainer in children

    Directory of Open Access Journals (Sweden)

    A Garg

    2014-01-01

    Full Text Available Aims: To compare the clinical efficacy of two space maintainers namely, conventional band and loop and Fiber Reinforced Composite Resin (FRCR space maintainers . Subjects and Methods: Thirty healthy children, aged 5 to 8 years were selected having at least two deciduous molars in different quadrants indicated for extraction or lost previously. FRCR space maintainer was placed in one quadrant and in the other quadrant band and loop space maintainer was cemented. All the patients were recalled at 1 st , 3 rd , and 6 th months for evaluation of both types of space maintainer. Patient acceptability, time taken, and clinical efficacy was recorded. Statistical analysis used: The observations thus obtained were subjected to statistical analysis using Chi- square test and Mann-Whitney U test. Results: Patient acceptability was greater in Group I (FRCR in comparison to Group II (band and loop space maintainer. The time taken by Group I was significantly lower as compared to that of Group II. In Group I, debonding of enamel, composite was the most common complication leading to failure followed by debonding of fiber composite. In Group II, cement loss was the most common complication leading to failure followed by slippage of band and fracture of loop. The success rates of Groups I and Group II weares 63.3% and 36.7%, respectively. Conclusion: The study concluded that FRCRFiber Reinforced Composite Resin (Ribbond space maintainers can be considered as viable alternative to the conventional band and loop space maintainers.

  12. Crystal structure of the complex of carboxypeptidase A with a strongly bound phosphonate in a new crystalline form: comparison with structures of other complexes.

    Science.gov (United States)

    Kim, H; Lipscomb, W N

    1990-06-12

    O-[[(1R)-[[N-(Phenylmethoxycarbonyl)-L-alanyl]amino]ethyl] hydroxyphosphinyl]-L-3-phenyllacetate [ZAAP(O)F], an analogue of (benzyloxycarbonyl)-Ala-Ala-Phe or (benzyloxycarbonyl)-Ala-Ala-phenyllactate, binds to carboxypeptidase A with great affinity (Ki = 3 pM). Similar phosphonates have been shown to be transition-state analogues of the CPA-catalyzed hydrolysis [Hanson, J. E., Kaplan, A. P., & Bartlett, P. A. (1989) Biochemistry 28, 6294-6305]. In the present study, the structure of the complex of this phosphonate with carboxypeptidase A has been determined by X-ray crystallography to a resolution of 2.0 A. The complex crystallizes in the space group P2(1)2(1)2(1) with cell dimensions a = 61.9 A, b = 67.2 A, and c = 76.2 A. The structure of the complex was solved by molecular replacement. Refinement of the structure against 20,776 unique reflections between 10.0 and 2.0 A yields a crystallographic residual of 0.193, including 140 water molecules. The two phosphinyl oxygens of the inhibitor bind to the active-site zinc at 2.2 A on the electrophilic (Arg-127) side and 3.1 A on the nucleophilic (Glu-270) side. Various features of the binding mode of this phosphonate inhibitor are consistent with the hypothesis that carboxypeptidase A catalyzed hydrolysis proceeds through a general-base mechanism in which the carbonyl carbon of the substrate is attacked by Zn-hydroxyl (or Zn-water). An unexpected feature of the bound inhibitor, the cis carbamoyl ester bond at the benzyloxycarbonyl linkage to alanine, allows the benzyloxycarbonyl phenyl ring of the inhibitor to interact favorably with Tyr-198. This complex structure is compared with previous structures of carboxypeptidase A, including the complexes with the potato inhibitor, a hydrated keto methylene substrate analogue, and a phosphonamidate inhibitor. Comparisons are also made with the complexes of thermolysin with some phosphonamidate inhibitors.

  13. Concept for an International Standard related to Space Weather Effects on Space Systems

    Science.gov (United States)

    Tobiska, W. Kent; Tomky, Alyssa

    There is great interest in developing an international standard related to space weather in order to specify the tools and parameters needed for space systems operations. In particular, a standard is important for satellite operators who may not be familiar with space weather. In addition, there are others who participate in space systems operations that would also benefit from such a document. For example, the developers of software systems that provide LEO satellite orbit determination, radio communication availability for scintillation events (GEO-to-ground L and UHF bands), GPS uncertainties, and the radiation environment from ground-to-space for commercial space tourism. These groups require recent historical data, current epoch specification, and forecast of space weather events into their automated or manual systems. Other examples are national government agencies that rely on space weather data provided by their organizations such as those represented in the International Space Environment Service (ISES) group of 14 national agencies. Designers, manufacturers, and launchers of space systems require real-time, operational space weather parameters that can be measured, monitored, or built into automated systems. Thus, a broad scope for the document will provide a useful international standard product to a variety of engineering and science domains. The structure of the document should contain a well-defined scope, consensus space weather terms and definitions, and internationally accepted descriptions of the main elements of space weather, its sources, and its effects upon space systems. Appendices will be useful for describing expanded material such as guidelines on how to use the standard, how to obtain specific space weather parameters, and short but detailed descriptions such as when best to use some parameters and not others; appendices provide a path for easily updating the standard since the domain of space weather is rapidly changing with new advances

  14. Nuclear power in space

    International Nuclear Information System (INIS)

    Aftergood, S.; Hafemeister, D.W.; Prilutsky, O.F.; Rodionov, S.N.; Primack, J.R.

    1991-01-01

    Nuclear reactors have provided energy for satellites-with nearly disastrous results. Now the US government is proposing to build nuclear-powered boosters to launch Star Wars defenses. These authors represent scientific groups that are opposed to the use of nuclear power in near space. The authors feel that the best course for space-borne reactors is to ban them from Earth orbit and use them in deep space

  15. Problem and Project Based Learning in Hybrid Spaces

    DEFF Research Database (Denmark)

    Ryberg, Thomas; Davidsen, Jacob; Hodgson, Vivien

    2016-01-01

    There is a need within networked learning to understand and conceptualise the interplay between digital and physical spaces or what we could term hybrid spaces. Therefore, we discuss a recent study of students from two different programmes who are engaged in long-term, group-based problem...... and project based learning. Based on interviews, workshops and observations of students’ actual group practices in open, shared and flexible spaces in Aalborg University (AAU), we identify and discuss how students incorporate networked and digital technologies into their group work and into the study places...... they create for themselves. We describe how in one of the programmes ‘nomadic’ groups of students used different technologies and spaces for ‘placemaking’. We then show how their experience and approach to collaborative work differs to that of the more static or ‘artisan’ groups of students in the other...

  16. The coadjoint orbit spaces of Diff(S1) and Teichmueller spaces

    International Nuclear Information System (INIS)

    Nag, S.; Verjovsky, A.

    1989-09-01

    Precisely two of the homogeneous spaces that appear as coadjoint orbits of the group of string reparametrizations (Diff (S 1 )) carry in a natural way the structure of infinite dimensional, holomorphically homogeneous complex analytic Kaehler manifolds. These are N = Diff (S 1 )/Rot (S 1 ) and M = Diff (S 1 )/Moeb (S 1 ). Note that N is a holomorphic disc fiber space over M. Now, M can be naturally considered as embedded in the classical universal Teichmueller space T(1), simply by noting that a diffeomorphism of S 1 is a quasisymmetric homeomorphism. T(1) is itself a homomorphically homogeneous complex Banach manifold. We prove in the first part of the paper that the inclusion of M in T(1) is complex analytic. In the latter portion of this paper it is shown that the unique homogeneous Kaehler metric carried by M = Diff (S 1 )/SL(2, R) induces precisely the Weil-Petersson metric on the Teichmueller space. This is via our identification of M as a holomorphic submanifold of universal Teichmueller space. Now recall that every Teichmueller space T(G) of finite or infinite dimension is contained canonically and holomorphically within T(1). Our computations allow us also to prove that every T(G), G any infinite Fuchsian group, projects out of M transversely. This last assertion is related to the ''fractal'' nature of G-invariant quasicircles, and to Mostow rigidity on the line. Our results thus connect the loop space approach to bosonic string theory with the sumover moduli (Polyakov path integral) approach. (author). 21 refs

  17. An analysis of pH, pO2 and pCO2 in the peritoneal fluid of dogs with ascites of various etiologies.

    Science.gov (United States)

    Glińska-Suchocka, K; Sławuta, P; Jankowski, M; Kubiak, K; Spużak, J; Borusewicz, P

    2016-01-01

    The aim of the study was to assess pH, pO2 and pCO2 in peritoneal fluid. The study was conducted on a group of 22 dogs with symptoms of ascites. Group 1 consisted of 4 dogs with adenocarcinoma, group 2--of 6 dogs with glomerulonephritis, group 3 of 8 dogs with hepatic cirrhosis and group 4 of 4 dogs with bacterial peritonitis. An abdominal cavity puncture was performed in all dogs and the fluid was drawn into a heparinized syringe in order to assess pH, pO2 and pCO2 . The analysis of pH in the peritoneal fluid revealed statistically significant differences between group 4 and groups 1 (p=0.01), 2 (p=0.01), and 3 (p=0.01). The lowest pH value compared to the other studied groups was recorded in group 4. In group 4, the pO2 was the lowest compared to the other groups (group 1 p=0.01, group 2 p=0.01, group 3 p=0.01). The value of pCO2 was the highest in group 4 compared to groups 1, 2, and 3. The study found statistically significant differences in pH, pCO2 and pCO2 between group 4 (the group of dogs with bacterial peritonitis) and the other groups of dogs. This was probably linked to the pathogenesis of peritonitis. As a result of an inflammatory reaction within the peritoneal cavity, there is an increase in fibrin accumulations leading to a decreased oxygen supply causing the oxidative glucose metabolism to change into a non-oxidative glucose metabolism. This, in turn, causes a decrease in pH, acidosis, and a low oxidoreduction potential. It also impairs phagocytosis and activates proteolytic enzymes which create ideal conditions for the growth of anaerobic bacteria. The obtained results indicate that the pH, pO2 and pCO2 may be used to differentiate bacterial peritonitis from ascites of other etiologies.

  18. Space Environmental Effects on Materials and Processes

    Science.gov (United States)

    Sabbann, Leslie M.

    2009-01-01

    The Materials and Processes (M&P) Branch of the Structural Engineering Division at Johnson Space Center (JSC) seeks to uphold the production of dependable space hardware through materials research, which fits into NASA's purpose of advancing human exploration, use, and development of space. The Space Environmental Effects projects fully support these Agency goals. Two tasks were assigned to support M&P. Both assignments were to further the research of material behavior outside of Earth's atmosphere in order to determine which materials are most durable and safe to use in space for mitigating risks. One project, the Materials on International Space Station Experiments (MISSE) task, was to compile data from International Space Station (ISS) experiments to pinpoint beneficial space hardware. The other project was researching the effects on composite materials of exposure to high doses of radiation for a Lunar habitat project.

  19. Structural, elastic, and electronic properties of compressed ZnP{sub 2}

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Hong-Mei [School of Physics and Electronic Engineering, Jiangsu Normal University, Xuzhou 221116 (China); Li, Yan-Ling, E-mail: ylli@jsnu.edu.cn [School of Physics and Electronic Engineering, Jiangsu Normal University, Xuzhou 221116 (China); Key Laboratory of Materials Physics, Institute of Solid State Physics, Chinese Academy of Sciences, Hefei 230031 (China); Zeng, Zhi [Key Laboratory of Materials Physics, Institute of Solid State Physics, Chinese Academy of Sciences, Hefei 230031 (China)

    2013-06-15

    The structural, elastic and electronic properties of compressed ZnP{sub 2} were investigated by first-principles total energy calculations. The optimized equilibrium structural parameters agree well with those of experiments for α-ZnP{sub 2} and β-ZnP{sub 2} at zero pressure. α-ZnP{sub 2} transforms into I4{sub 1}/22 phase (referred as γ-ZnP{sub 2}) at 11 GPa, which is an indirect band-gap (∼0.78 eV) semiconductor. Space group of low pressure phase is the subgroup of that of high pressure phase. The calculated elastic constants for α-ZnP{sub 2} and β-ZnP{sub 2} at zero pressure as well as γ-ZnP{sub 2} at phase transition pressure determine their stability mechanically. Phonon calculation confirms dynamical stability of γ-ZnP{sub 2}.

  20. The generalization of the Schur multipliers of Bieberbach groups

    Science.gov (United States)

    Masri, Rohaidah; Hassim, Hazzirah Izzati Mat; Sarmin, Nor Haniza; Ali, Nor Muhainiah Mohd; Idrus, Nor'ashiqin Mohd

    2014-12-01

    The Schur multiplier is the second homology group of a group. It has been found to be isomorphic to the kernel of a homomorphism which maps the elements in the exterior square of the group to the elements in its derived subgroup. Meanwhile, a Bieberbach group is a space group which is a discrete cocompact group of isometries of oriented Euclidean space. In this research, the Schur multipliers of Bieberbach groups with cyclic point group of order two of finite dimension are computed.

  1. Crystal structure of dimethylformamidium bis(trifluoromethanesulfonyl)amide: an ionic liquid

    OpenAIRE

    Allan Jay P. Cardenas; Molly O'Hagan

    2016-01-01

    At 100?K, the title mol?ecular salt, C3H8NO+?C2F6NO4S2 ?, has ortho?rhom?bic (P212121) symmetry; the amino H atom of bis?(tri?fluoro?methane?sulfon?yl)amine (HNTf2) was transferred to the basic O atom of di?methyl?formamide (DMF) when the ionic liquid components were mixed. The structure displays an O?H?N hydrogen bond, which links the cation to the anion, which is reinforced by a non-conventional C?H?O inter?action, generating an R 2 2(7) loop. A further very weak C?H?O inter?action generate...

  2. Quasi quantum group covariant q-oscillators

    International Nuclear Information System (INIS)

    Schomerus, V.

    1992-05-01

    If q is a p-th root of unity there exists a quasi-co-associative truncated quantum group algebra U T q (sl 2 ) whose indecomposable representations are the physical representations of U q (sl 2 ), whose co-product yields the truneated tensor product of physical representations of U q (sl 2 ), and whose R-matrix satisfies quasi Yang Baxter equations. For primitive p-th roots q, we consider a 2-dimensional q-oscillator which admits U T q (sl 2 ) as a symmetry algebra. Its wave functions lie in a space F T q of 'functions on the truncated quantum plane', i.e. of polynomials in noncommuting complex coordinate functions z a , on which multiplication operators Z a and the elements of U T q (sl 2 ) can act. This illustrates the concept of quasi quantum planes. Due to the truncation, the Hilbert space of states is finite dimensional. The subspaces F T(n) of monomials in x a of n-th degree vanish for n ≥ p-1, and F T(n) carries the 2J+1 dimensional irreducible representation of U T q (sl 2 ) if n=2J, J=0, 1/2, ... 1/2(p-2). Partial derivatives δ a are introduced. We find a *-operation on the algebra of multiplication operators Z i and derivatives δ b such that the adjoints Z * a act as differentiation on the truncated quantum plane. Multiplication operators Z a ('creation operators') and their adjoints ('annihilation operators') obey q -1/2 -commutation relations. The *-operation is used to determine a positive definite scalar product on the truncated quantum plane F T q . Some natural candidates of Hamiltonians for the q-oscillators are determined. (orig./HSI)

  3. Nuclear safety policy working group recommendations on nuclear propulsion safety for the space exploration initiative

    Science.gov (United States)

    Marshall, Albert C.; Lee, James H.; Mcculloch, William H.; Sawyer, J. Charles, Jr.; Bari, Robert A.; Cullingford, Hatice S.; Hardy, Alva C.; Niederauer, George F.; Remp, Kerry; Rice, John W.

    1993-01-01

    An interagency Nuclear Safety Working Group (NSPWG) was chartered to recommend nuclear safety policy, requirements, and guidelines for the Space Exploration Initiative (SEI) nuclear propulsion program. These recommendations, which are contained in this report, should facilitate the implementation of mission planning and conceptual design studies. The NSPWG has recommended a top-level policy to provide the guiding principles for the development and implementation of the SEI nuclear propulsion safety program. In addition, the NSPWG has reviewed safety issues for nuclear propulsion and recommended top-level safety requirements and guidelines to address these issues. These recommendations should be useful for the development of the program's top-level requirements for safety functions (referred to as Safety Functional Requirements). The safety requirements and guidelines address the following topics: reactor start-up, inadvertent criticality, radiological release and exposure, disposal, entry, safeguards, risk/reliability, operational safety, ground testing, and other considerations.

  4. Summary of Research 1997, Interdisciplinary Academic Groups

    National Research Council Canada - National Science Library

    Boger, Dan

    1999-01-01

    This report contains information of research projects in the interdisciplinary groups, Command, Control, and Communications Academic Group, Information Warfare Academic Group, Space Systems Academic...

  5. Neutron diffraction studies on Ca1− xBaxZr4P6O24 solid solutions

    Indian Academy of Sciences (India)

    P6O24 compositions from combined Rietveld refinements of powder X-ray and neutron diffraction data. All the studied compositions crystallize in rhombohedral lattice (space group R-3 No. 148). A continuous solid solution is concluded from ...

  6. The Extended Relativity Theory in Clifford Spaces

    CERN Document Server

    Castro, C

    2004-01-01

    A brief review of some of the most important features of the Extended Relativity theory in Clifford-spaces ( $C$-spaces) is presented whose " point" coordinates are noncommuting Clifford-valued quantities and which incoporate the lines, areas, volumes, .... degrees of freedom associated with the collective particle, string, membrane, ... dynamics of the $p$-loop histories (closed p-branes) living in target $D$-dimensional spacetime backgrounds. $C$-space Relativity naturally incoporates the ideas of an invariant length (Planck scale), maximal acceleration, noncommuting coordinates, supersymmetry, holography, superluminal propagation, higher derivative gravity with torsion and variable dimensions/signatures that allows to study the dynamics of all (closed ) p-branes, for all values of $ p $, in a unified footing. It resolves the ordering ambiguities in QFT and the problem of time in Cosmology. A discussion of the maximal-acceleration Relativity principle in phase-spaces follows along with the study of the inva...

  7. 2004 Space Report: Environment and Strategy for Space Research at NATO's Research and Technology Organisation (RTO)

    Science.gov (United States)

    Woods-Vedeler, Jessica A.

    2007-01-01

    This report describes the motivation for and a strategy to enhance the NATO Research and Technology Organisation's (RTO) current space research effort to reflect NATO's growing military dependence on space systems. Such systems and services provided by these systems are critical elements of military operations. NATO uses space systems for operational planning and support, communication, radio navigation, multi-sensor and multi-domain demonstrations. Such systems are also used to promote regional stability. A quantitative analysis of work related to space in the NATO RTO showed that during the period of 1998 - 2004, 5% of the research pursued in the NATO RTO has been clearly focused on space applications. Challenging environmental and organizational barriers for increasing RTO space research were identified. In part, these include lack of sufficient space expertise representation on panels, the military sensitivity of space, current panel work loads and the need for specific technical recommendations from peers. A strategy for enhancing space research in the RTO is to create a limited-life Space Advisory Group (SAG) composed of Space Expert Consultants who are panel members with appropriate expertise and additional expertise from the nations. The SAG will recommend and find support in the nations for specific technical activities related to space in the areas of Space Science, Remote Sensing Data Analysis, Spacecraft Systems, Surveillance and Early Warning, Training and Simulation and Policy. An RTO Space Advisory Group will provide an organizational mechanism to gain recognition of RTO as a forum for trans-Atlantic defence space research and to enhance space research activities.

  8. Esrange Space Center, a Gate to Space

    Science.gov (United States)

    Widell, Ola

    Swedish Space Corporation (SSC) is operating the Esrange Space Center in northern Sweden. Space operations have been performed for more than 40 years. We have a unique combination of maintaining balloon and rocket launch operations, and building payloads, providing space vehicles and service systems. Sub-orbital rocket flights with land recovery and short to long duration balloon flights up to weeks are offered. The geographical location, land recovery area and the long term experience makes Swedish Space Corporation and Esrange to an ideal gate for space activities. Stratospheric balloons are primarily used in supporting atmospheric research, validation of satellites and testing of space systems. Balloon operations have been carried out at Esrange since 1974. A large number of balloon flights are yearly launched in cooperation with CNES, France. Since 2005 NASA/CSBF and Esrange provide long duration balloon flights to North America. Flight durations up to 5 days with giant balloons (1.2 Million cubic metres) carrying heavy payload (up to 2500kg) with astronomical instruments has been performed. Balloons are also used as a crane for lifting space vehicles or parachute systems to be dropped and tested from high altitude. Many scientific groups both in US, Europe and Japan have indicated a great need of long duration balloon flights. Esrange will perform a technical polar circum balloon flight during the summer 2008 testing balloon systems and flight technique. We are also working on a permission giving us the opportunity on a circular stratospheric balloon flight around the North Pole.

  9. Blood Group Antigens C, Lub and P1 May Have a Role in HIV Infection in Africans.

    Science.gov (United States)

    Motswaledi, Modisa Sekhamo; Kasvosve, Ishmael; Oguntibeju, Oluwafemi Omoniyi

    2016-01-01

    Botswana is among the world's countries with the highest rates of HIV infection. It is not known whether or not this susceptibility to infection is due to genetic factors in the population. Accumulating evidence, however, points to the role of erythrocytes as potential mediators of infection. We therefore sought to establish the role, if any, of some erythrocyte antigens in HIV infection in a cross-section of the population. 348 (346 HIV-negative and 2 HIV-positive) samples were obtained from the National Blood Transfusion Service as residual samples, while 194 HIV-positive samples were obtained from the Botswana-Harvard HIV Reference Laboratory. Samples were grouped for twenty three antigens. Chi-square or Fischer Exact analyses were used to compare the frequencies of the antigens in the two groups. A stepwise, binary logistic regression was used to study the interaction of the various antigens in the light of HIV-status. The Rh antigens C and E were associated with HIV-negative status, while blood group Jka, P1 and Lub were associated with HIV-positive status. A stepwise binary logistic regression analysis yielded group C as the most significant protective blood group while Lub and P1 were associated with significantly higher odds ratio in favor of HIV-infection. The lower-risk-associated group C was significantly lower in Africans compared to published data for Caucasians and might partially explain the difference in susceptibility to HIV-1. The most influential antigen C, which also appears to be protective, is significantly lower in Africans than published data for Caucasians or Asians. On the other hand, there appear to be multiple antigens associated with increased risk that may override the protective role of C. A study of the distribution of these antigens in other populations may shed light on their roles in the HIV pandemic.

  10. Resonating-group study of p + α scattering from 68 to 125 MeV

    International Nuclear Information System (INIS)

    Thompson, D.R.; Brown, R.E.; LeMere, M.; Tang, Y.C.

    1977-01-01

    The resonating-group method, together with a phenomenological consideration of reaction effects, is used to analyze p + α scattering data at the relatively high c.m. energies of 68, 80, and 124.8 MeV. The nucleon-nucleon potential employed contains a weakly repulsive core and yields a reasonably satisfactory description of not only the two-nucleon scattering data but also the essential properties of the α particle. The result shows that satisfactory agreement with experiment can be obtained. In particular, it is found that, because of the use of a totally antisymmetric wave function, the scattering behavior at large angles is adequately described

  11. On the structure and applications of the Bondi-Metzner-Sachs group

    Science.gov (United States)

    Alessio, Francesco; Esposito, Giampiero

    This work is a pedagogical review dedicated to a modern description of the Bondi-Metzner-Sachs (BMS) group. Minkowski space-time has an interesting and useful group of isometries, but, for a generic space-time, the isometry group is simply the identity and hence provides no significant informations. Yet symmetry groups have important role to play in physics; in particular, the Poincaré group describing the isometries of Minkowski space-time plays a role in the standard definitions of energy-momentum and angular-momentum. For this reason alone it would seem to be important to look for a generalization of the concept of isometry group that can apply in a useful way to suitable curved space-times. The curved space-times that will be taken into account are the ones that suitably approach, at infinity, Minkowski space-time. In particular we will focus on asymptotically flat space-times. In this work, the concept of asymptotic symmetry group of those space-times will be studied. In the first two sections we derive the asymptotic group following the classical approach which was basically developed by Bondi, van den Burg, Metzner and Sachs. This is essentially the group of transformations between coordinate systems of a certain type in asymptotically flat space-times. In the third section the conformal method and the notion of “asymptotic simplicity” are introduced, following mainly the works of Penrose. This section prepares us for another derivation of the BMS group which will involve the conformal structure, and is thus more geometrical and fundamental. In the subsequent sections we discuss the properties of the BMS group, e.g. its algebra and the possibility to obtain as its subgroup the Poincaré group, as we may expect. The paper ends with a review of the BMS invariance properties of classical gravitational scattering discovered by Strominger, that are finding application to black hole physics and quantum gravity in the literature.

  12. Radiographic assessment of lower third molar eruption in different anteroposterior skeletal patterns and age-related groups.

    Science.gov (United States)

    Jakovljevic, Aleksandar; Lazic, Emira; Soldatovic, Ivan; Nedeljkovic, Nenad; Andric, Miroslav

    2015-07-01

    To analyze radiographic predictors for lower third molar eruption among subjects with different anteroposterior skeletal relations and of different age groups. In total, 300 lower third molars were recorded on diagnostic digital orthopantomograms (DPTs) and lateral cephalograms (LCs). The radiographs were grouped according to sagittal intermaxillary angle (ANB), subject age, and level of lower third molar eruption. The DPT was used to analyze retromolar space, mesiodistal crown width, space/width ratio, third and second molar angulation (α, γ), third molar inclination (β), and gonion angle. The LC was used to determine ANB, angles of maxillar and mandibular prognathism (SNA, SNB), mandibular plane angle (SN/MP), and mandibular lengths. A logistic regression model was created using the statistically significant predictors. The logistic regression analysis revealed a statistically significant impact of β angle and distance between gonion and gnathion (Go-Gn) on the level of lower third molar eruption (P third molar impaction rate was significantly higher in the adult subgroup with the Class II (62.3%) compared with Class III subjects (31.7%; P third molar eruption were measured in Class III subjects. For valid estimation of mandibular third molar eruption, certain linear and angular measures (β angle, Go-Gn), as well as the size of the retromolar space, need to be considered.

  13. DOT-IV two-dimensional discrete ordinates transport code with space-dependent mesh and quadrature

    International Nuclear Information System (INIS)

    Rhoades, W.A.; Simpson, D.B.; Childs, R.L.; Engle, W.W. Jr.

    1979-01-01

    DOT IV is designed to allow very large problems to be solved on a wide range of computers and memory arrangements. New flexibility in both space-mesh and directional-quadrature specification is allowed. For example, the radial mesh in an R-Z problem can vary with axial position. The directional quadrature can vary with both space and energy group. Several features improve performance on both deep penetration and criticality problems. The program has been checked and used extensively on several types of computers. All of the features have been insured operable except the following two, which must not be used: criticality searches and P/sub L/ variable by group or material. Diffusion theory problems must not use internal or external boundary sources, variable mesh, or variable quadrature. A diffusion iteration cannot produce internal boundary source output or ''angular flux tape.'' The P 1 module is very limited. The special geometries, INGEOM greater than or equal to 10, have not been completely checked and are not guaranteed. 7 figures, 1 table

  14. Comparative Evaluation of the Pharyngeal Airway Space in Unilateral and Bilateral Cleft Lip and Palate Individuals With Noncleft Individuals: A Cone Beam Computed Tomography Study.

    Science.gov (United States)

    Gandedkar, Narayan H; Chng, Chai Kiat; Basheer, Mohammad Abdul; Chen, Por Yong; Yeow, Vincent Kok Leng

    2017-09-01

      To evaluate the pharyngeal airway space changes in complete unilateral cleft lip and palate (UCLP) and bilateral cleft lip and palate (BCLP) individuals, and compare with age and sex-matched noncleft (NC) control subjects.   Retrospective study.   Cleft and Craniofacial Centre, KK Women's and Children's Hospital, Singapore.   Twenty UCLP (mean age: 13.4 ± 0.5 years), 18 BCLP (mean age: 13.5 ± 0.5 years) and 20 skeletal Class I subjects (mean age: 13.4 ± 0.6 years) were included in the study. Cone beam computed tomography scans were assessed for pharyngeal airway space (PAS) (oropharyngeal, nasopharyngeal, total airway space volume), and compared with PAS of age and sex-matched skeletal Class I NC individuals.   Pharyngeal airway space showed statistically significant differences in the UCLP, BCLP, and NC control subjects. Oropharyngeal (9338 ± 1108 mm 3 , P space (12 250 ± 1185 mm 3 , P .05).   The pharyngeal airway space was significantly reduced in the BCLP group than were those in UCLP and control groups. This reduced PAS should be taken into account when planning treatment for these individuals.

  15. A Local Scalable Distributed EM Algorithm for Large P2P Networks

    Data.gov (United States)

    National Aeronautics and Space Administration — his paper describes a local and distributed expectation maximization algorithm for learning parameters of Gaussian mixture models (GMM) in large peer-to-peer (P2P)...

  16. A note on totally normal spaces

    International Nuclear Information System (INIS)

    Zougdani, H.K.

    1990-10-01

    In this note we give the necessary and sufficient condition for a topological space X such that the product space X x Y is totally normal for any (non discrete) metric space Y, and we show that a totally normal p-space need not be a perfectly normal in general, which makes Theorem 2 doubtful. (author). 6 refs

  17. Evaluation of the Communication Between Arachnoid Cysts and Neighboring Cerebrospinal Fluid Spaces by T2W 3D-SPACE With Variant Flip-Angle Technique at 3 T.

    Science.gov (United States)

    Algin, Oktay

    2018-05-21

    Phase-contrast cine magnetic resonance imaging (PC-MRI) is a widely used technique for determination of possible communication of arachnoid cysts (ACs). Three-dimensional (3D) sampling perfection with application-optimized contrasts using different flip-angle evolutions (3D-SPACE) technique is a relatively new method for 3D isotropic scanning of the entire cranium within a short time. In this research, the usage of the 3D-SPACE technique in differentiation of communicating or noncommunicating type ACs was evaluated. Thirty-five ACs in 34 patients were retrospectively examined. The 3D-SPACE, PC-MRI, and contrast material-enhanced cisternography (if present) images of the patients were analyzed. Each cyst was described according to cyst size/location, third ventricle diameter, Evans index, and presence of hydrocephalus. Communication was defined as absent (score 0), suspected (score 1), or present (score 2) on each sequence. Results of PC-MRI or cisternography (if available) examinations were used as criterion standard techniques to categorize all cysts as communicating or noncommunicating type. The results of 3D-SPACE were compared with criterion standard techniques. The comparisons between groups were performed using Mann-Whitney and Fisher exact tests. For demonstration of communication status of the cysts, criterion standard test results and 3D-SPACE findings were almost in perfect harmony (κ[95% confidence interval: 0.94]; P SPACE findings correlated with other final results at a rate of 97%. There is a positive correlation with third ventricular diameters and Evans index for all patients (r = 0.77, P SPACE technique is an easy, useful, and noninvasive alternative for the evaluation of morphology, topographical relationships, and communication status of ACs.

  18. Girls InSpace project: A new space physics outreach initiative.

    Science.gov (United States)

    Abe Pacini, A.; Tegbaru, D.; Max, A., Sr.

    2017-12-01

    We present here the concept and state-of-art of the new space physics youth education and outreach initiative called "Girls InSpace project". The project goal is to spread quality scientific information to underrepresented groups, motivate girls in STEM and promote gender equality in the Space Physics area. Initially, the "Girls InSpace project" will be available in two languages (Portuguese and English) aiming to reach out to the youth of Brazil, United States, Nigeria, South Africa, Ethiopia and Angola. Eventually, the material will be translated to French and Spanish, focusing on French-speaking countries in Africa and Latin America. The project spans a collection of four books about a group of young girls and their adventures (always related to the sky and simultaneously introducing earth and space science concepts). Ancillary content such as a webpage, mobile applications and lesson plans are also in development. The books were written by a Space Physicist PhD woman, illustrated by a Brazilian young artist and commented by senior female scientists, creating positive role models for the next generation of girls in STEM. The story lines were drawn around the selected topics of astronomy and space physics, introducing scientific information to the target readers (girls from 8-13 years old) and enhancing their curiosity and critical thinking. The books instill the readers to explore the available extra web-content (with images, videos, interviews with scientists, real space data, coding and deeper scientific information) and game apps (with Virtual Reality components and real space images). Moreover, for teachers K-12, a collection of lesson plans will be made available, aiming to facilitate scientific content discussed in the books and inside classroom environments. Gender bias in STEM reported earlier this year in Nature and based on a study of the American Geophysical Union's member database showed a competitive disadvantage for women in the Earth and Space

  19. Theoretical study on the interactions between chlordecone hydrate and acidic surface groups of activated carbon under basic pH conditions.

    Science.gov (United States)

    Melchor-Rodríguez, Kenia; Gamboa-Carballo, Juan José; Ferino-Pérez, Anthuan; Passé-Coutrin, Nady; Gaspard, Sarra; Jáuregui-Haza, Ulises Javier

    2018-05-01

    A theoretical study of the influence of acidic surface groups (SG) of activated carbon (AC) on chlordecone hydrate (CLDh) adsorption is presented, in order to help understanding the adsorption process under basic pH conditions. A seven rings aromatic system (coronene) with a functional group in the edge was used as a simplified model of AC to evaluate the influence of SG in the course of adsorption from aqueous solution at basic pH conditions. Two SG were modeled in their deprotonated form: carboxyl and hydroxyl (COO - and O - ), interacting with CLDh. In order to model the solvation process, all systems under study were calculated with up to three water molecules. Multiple Minima Hypersurface (MMH) methodology was employed to study the interactions of CLDh with SG on AC using PM7 semiempirical Hamiltonian, to explore the potential energy surfaces of the systems and evaluate their thermodynamic association energies. The re-optimization of representative structures obtained from MMH was done using M06-2X Density Functional Theory. The Quantum Theory of Atoms in Molecules (QTAIM) was used to characterize the interaction types. As result, the association of CLDh with acidic SG at basic pH conditions preferentially occurs between the two alcohol groups of CLDh with COO - and O - groups and by dispersive interactions of chlorine atoms of CLDh with the graphitic surface. On the other hand, the presence of covalent interactions between the negatively charged oxygen of SG and one hydrogen atom of CLDh alcohol groups (O - ⋯HO interactions) without water molecules, was confirmed by QTAIM study. It can be concluded that the interactions of CLDh with acidic SG of AC under basic pH conditions confirms the physical mechanisms of adsorption process. Copyright © 2018 Elsevier Inc. All rights reserved.

  20. pO2 and pCO2 increment in post-dialyzer blood: the role of dialysate.

    Science.gov (United States)

    Sombolos, Kostas I; Bamichas, Gerasimos I; Christidou, Fotini N; Gionanlis, Lazaros D; Karagianni, Anna C; Anagnostopoulos, Theodoros C; Natse, Taïsir A

    2005-11-01

    Blood returning from a dialyzer during hemodialysis has a higher pO2 and pCO2 content than blood entering the dialyzer, and this has been attributed to the dialysate. The present study investigates this phenomenon. Acid-base and blood-gas parameters (pH, pO2, pCO2 and HCO3) were measured in three groups of stable chronic hemodialysis patients (A, B, and C) undergoing high-flux hemodialysis. In group A (n = 15), "arterial" (a) and "venous" (v) samples were withdrawn simultaneously before dialysis (samples A0), 5 min after circulation of the blood with the dialysate in the by-pass mode (samples A5), and 5 min after high-flux hemodialysis at a zero ultrafiltration rate (samples A10). In group B (n = 11) (a) and (v) samples were withdrawn simultaneously before dialysis (samples B0), 5 min after isolated-ultrafiltration with closed dialysate ports ("isolated-closed" ultrafiltration) (samples B5), and 5 min after high-flux hemodialysis at a zero ultrafiltration rate (samples B10). In group C (n = 14), after an initial arterial blood sample withdrawal before hemodialysis (sample C0), high-flux hemodialysis at a zero ultrafiltration rate was initiated. Five minutes later, blood and dialysate samples were withdrawn simultaneously from the hemodialysis lines (samples C5). In all cases blood and dialysate (bicarbonate) flow rates were set at 0.300 and 0.700 L/min, respectively. FLX-18 hemodialyzers (membrane PEPA 1.8 m2) were used in this study. Analysis of variance revealed significant changes only in venous samples. A comparison of arterial and venous samples revealed no differences between groups A and B before the initiation of dialysis (A0a vs. A0v and B0a vs. B0v, P = NS). The pO2 content was higher in A5v samples than in A5a samples (83.5 +/- 11.2 vs. 88.8 +/- 14.0 mm Hg, P pO2, pCO2, and HCO3 in comparison to A10v samples (P pO2 and pCO2 values in A5v and A10v samples increased by 6.3% and 12.1% and by 1.29% and 52% in comparison to corresponding values of A5a and A10

  1. Block Ignition Inertial Confinement Fusion (ICF) with Condensed Matter Cluster Type Targets for p-B11 Powered Space Propulsion

    International Nuclear Information System (INIS)

    Miley, George H.; Hora, H.; Badziak, J.; Wolowski, J.; Sheng Zhengming; Zhang Jie; Osman, F.; Zhang Weiyan; Tuhe Xia

    2009-01-01

    The use of laser-driven Inertial Confinement Fusion (ICF) for space propulsion has been the subject of several earlier conceptual design studies, (see: Orth, 1998; and other references therein). However, these studies were based on older ICF technology using either 'direct' or 'in-direct x-ray driven' type target irradiation. Important new directions have opened for laser ICF in recent years following the development of 'chirped' lasers capable of ultra short pulses with powers of TW up to few PW which leads to the concept of 'fast ignition (FI)' to achieve higher energy gains from target implosions. In a recent publication the authors showed that use of a modified type of FI, termed 'block ignition' (Miley et al., 2008), could meet many of the requirements anticipated (but not then available) by the designs of the Vehicle for Interplanetary Space Transport Applications (VISTA) ICF fusion propulsion ship (Orth, 2008) for deep space missions. Subsequently the first author devised and presented concepts for imbedding high density condensed matter 'clusters' of deuterium into the target to obtain ultra high local fusion reaction rates (Miley, 2008). Such rates are possible due to the high density of the clusters (over an order of magnitude above cryogenic deuterium). Once compressed by the implosion, the yet higher density gives an ultra high reaction rate over the cluster volume since the fusion rate is proportional to the square of the fuel density. Most recently, a new discovery discussed here indicates that the target matrix could be composed of B 11 with proton clusters imbedded. This then makes p-B 11 fusion practical, assuming all of the physics issues such as stability of the clusters during compression are resolved. Indeed, p-B 11 power is ideal for fusion propulsion since it has a minimum of unwanted side products while giving most of the reaction energy to energetic alpha particles which can be directed into an exhaust (propulsion) nozzle. Power plants

  2. Block Ignition Inertial Confinement Fusion (ICF) with Condensed Matter Cluster Type Targets for p-B11 Powered Space Propulsion

    Science.gov (United States)

    Miley, George H.; Hora, H.; Badziak, J.; Wolowski, J.; Sheng, Zheng-Ming; Zhang, Jie; Osman, F.; Zhang, Weiyan; tu He, Xia

    2009-03-01

    The use of laser-driven Inertial Confinement Fusion (ICF) for space propulsion has been the subject of several earlier conceptual design studies, (see: Orth, 1998; and other references therein). However, these studies were based on older ICF technology using either "direct "or "in-direct x-ray driven" type target irradiation. Important new directions have opened for laser ICF in recent years following the development of "chirped" lasers capable of ultra short pulses with powers of TW up to few PW which leads to the concept of "fast ignition (FI)" to achieve higher energy gains from target implosions. In a recent publication the authors showed that use of a modified type of FI, termed "block ignition" (Miley et al., 2008), could meet many of the requirements anticipated (but not then available) by the designs of the Vehicle for Interplanetary Space Transport Applications (VISTA) ICF fusion propulsion ship (Orth, 2008) for deep space missions. Subsequently the first author devised and presented concepts for imbedding high density condensed matter "clusters" of deuterium into the target to obtain ultra high local fusion reaction rates (Miley, 2008). Such rates are possible due to the high density of the clusters (over an order of magnitude above cryogenic deuterium). Once compressed by the implosion, the yet higher density gives an ultra high reaction rate over the cluster volume since the fusion rate is proportional to the square of the fuel density. Most recently, a new discovery discussed here indicates that the target matrix could be composed of B11 with proton clusters imbedded. This then makes p-B11 fusion practical, assuming all of the physics issues such as stability of the clusters during compression are resolved. Indeed, p-B11 power is ideal for fusion propulsion since it has a minimum of unwanted side products while giving most of the reaction energy to energetic alpha particles which can be directed into an exhaust (propulsion) nozzle. Power plants using p

  3. Spaceflight Effects on Cytochrome P450 Content in Mouse Liver.

    Directory of Open Access Journals (Sweden)

    Natalia Moskaleva

    Full Text Available Hard conditions of long-term manned spaceflight can affect functions of many biological systems including a system of drug metabolism. The cytochrome P450 (CYP superfamily plays a key role in the drug metabolism. In this study we examined the hepatic content of some P450 isoforms in mice exposed to 30 days of space flight and microgravity. The CYP content was established by the mass-spectrometric method of selected reaction monitoring (SRM. Significant changes in the CYP2C29, CYP2E1 and CYP1A2 contents were detected in mice of the flight group compared to the ground control group. Within seven days after landing and corresponding recovery period changes in the content of CYP2C29 and CYP1A2 returned to the control level, while the CYP2E1 level remained elevated. The induction of enzyme observed in the mice in the conditions of the spaceflight could lead to an accelerated biotransformation and change in efficiency of pharmacological agents, metabolizing by corresponding CYP isoforms. Such possibility of an individual pharmacological response to medication during long-term spaceflights and early period of postflight adaptation should be taken into account in space medicine.

  4. Quantum groups: Geometry and applications

    International Nuclear Information System (INIS)

    Chu, C.S.

    1996-01-01

    The main theme of this thesis is a study of the geometry of quantum groups and quantum spaces, with the hope that they will be useful for the construction of quantum field theory with quantum group symmetry. The main tool used is the Faddeev-Reshetikhin-Takhtajan description of quantum groups. A few content-rich examples of quantum complex spaces with quantum group symmetry are treated in details. In chapter 1, the author reviews some of the basic concepts and notions for Hopf algebras and other background materials. In chapter 2, he studies the vector fields of quantum groups. A compact realization of these vector fields as pseudodifferential operators acting on the linear quantum spaces is given. In chapter 3, he describes the quantum sphere as a complex quantum manifold by means of a quantum stereographic projection. A covariant calculus is introduced. An interesting property of this calculus is the existence of a one-form realization of the exterior differential operator. The concept of a braided comodule is introduced and a braided algebra of quantum spheres is constructed. In chapter 4, the author considers the more general higher dimensional quantum complex projective spaces and the quantum Grassman manifolds. Differential calculus, integration and braiding can be introduced as in the one dimensional case. Finally, in chapter 5, he studies the framework of quantum principal bundle and construct the q-deformed Dirac monopole as a quantum principal bundle with a quantum sphere as the base and a U(1) with non-commutative calculus as the fiber. The first Chern class can be introduced and integrated to give the monopole charge

  5. Purification, crystallization and preliminary X-ray diffraction analysis of disease-related mutants of p97

    International Nuclear Information System (INIS)

    Tang, Wai-Kwan; Li, Dongyang; Esser, Lothar; Xia, Di

    2009-01-01

    Mutations in the human AAA+ protein p97 cause a disease in humans called IBMPFD. How these mutations affect the structure and function of p97 is unknown. Here, the crystallization of three disease-related mutants of p97 in the presence of ATPγS are reported. The human type II AAA+ protein p97 participates in various cellular activities, presumably through its involvement in the ubiquitin–proteasome degradation pathway. Mutations in p97 have been implicated in patients with inclusion-body myopathy associated with Paget’s disease of the bone and frontotemporal dementia (IBMPFD). In this work, three mutant p97 N-D1 fragments, R86A, R95G and R155H, were crystallized in the presence of ATPγS with PEG 3350 as a main precipitant, yielding two different crystal forms. The R155H mutant crystal belonged to space group R3, with unit-cell parameters in the hexagonal setting of a = b = 134.2, c = 182.9 Å, and was merohedrally twinned, with an estimated twin fraction of 0.34. The crystals of the R86A and R95G mutants belonged to space group P1, with similar unit-cell parameters of a = 90.89, b = 102.6, c = 107.2 Å, α = 97.5, β = 90.6, γ = 91.5° and a = 92.76, b = 103.7, c = 107.7 Å, α = 97.7, β = 91.9, γ = 89.7°, respectively

  6. Arithmetically Cohen-Macaulay sets of points in P^1 x P^1

    CERN Document Server

    Guardo, Elena

    2015-01-01

    This brief presents a solution to the interpolation problem for arithmetically Cohen-Macaulay (ACM) sets of points in the multiprojective space P^1 x P^1.  It collects the various current threads in the literature on this topic with the aim of providing a self-contained, unified introduction while also advancing some new ideas.  The relevant constructions related to multiprojective spaces are reviewed first, followed by the basic properties of points in P^1 x P^1, the bigraded Hilbert function, and ACM sets of points.  The authors then show how, using a combinatorial description of ACM points in P^1 x P^1, the bigraded Hilbert function can be computed and, as a result, solve the interpolation problem.  In subsequent chapters, they consider fat points and double points in P^1 x P^1 and demonstrate how to use their results to answer questions and problems of interest in commutative algebra.  Throughout the book, chapters end with a brief historical overview, citations of related results, and, where relevan...

  7. NASA study of cataract in astronauts (NASCA). Report 1: Cross-sectional study of the relationship of exposure to space radiation and risk of lens opacity.

    Science.gov (United States)

    Chylack, Leo T; Peterson, Leif E; Feiveson, Alan H; Wear, Mary L; Manuel, F Keith; Tung, William H; Hardy, Dale S; Marak, Lisa J; Cucinotta, Francis A

    2009-07-01

    The NASA Study of Cataract in Astronauts (NASCA) is a 5-year longitudinal study of the effect of space radiation exposure on the severity/progression of nuclear, cortical and posterior subcapsular (PSC) lens opacities. Here we report on baseline data that will be used over the course of the longitudinal study. Participants include 171 consenting astronauts who flew at least one mission in space and a comparison group made up of three components: (a) 53 astronauts who had not flown in space, (b) 95 military aircrew personnel, and (c) 99 non-aircrew ground-based comparison subjects. Continuous measures of nuclear, cortical and PSC lens opacities were derived from Nidek EAS 1000 digitized images. Age, demographics, general health, nutritional intake and solar ocular exposure were measured at baseline. Astronauts who flew at least one mission were matched to comparison subjects using propensity scores based on demographic characteristics and medical history stratified by gender and smoking (ever/never). The cross-sectional data for matched subjects were analyzed by fitting customized non-normal regression models to examine the effect of space radiation on each measure of opacity. The variability and median of cortical cataracts were significantly higher for exposed astronauts than for nonexposed astronauts and comparison subjects with similar ages (P=0.015). Galactic cosmic space radiation (GCR) may be linked to increased PSC area (P=0.056) and the number of PSC centers (P=0.095). Within the astronaut group, PSC size was greater in subjects with higher space radiation doses (P=0.016). No association was found between space radiation and nuclear cataracts. Cross-sectional data analysis revealed a small deleterious effect of space radiation for cortical cataracts and possibly for PSC cataracts. These results suggest increased cataract risks at smaller radiation doses than have been reported previously.

  8. LandScape: a simple method to aggregate p--Values and other stochastic variables without a priori grouping

    DEFF Research Database (Denmark)

    Wiuf, Carsten; Pallesen, Jonatan; Foldager, Leslie

    2016-01-01

    variables without assuming a priori defined groups. We provide different ways to evaluate the significance of the aggregated variables based on theoretical considerations and resampling techniques, and show that under certain assumptions the FWER is controlled in the strong sense. Validity of the method...... and the results might depend on the chosen criteria. Methods that summarize, or aggregate, test statistics or p-values, without relying on a priori criteria, are therefore desirable. We present a simple method to aggregate a sequence of stochastic variables, such as test statistics or p-values, into fewer...

  9. On irreducible representations of the ultrahyperbolic BMS group

    International Nuclear Information System (INIS)

    McCarthy, Patrick J.; Melas, Evangelos

    2003-01-01

    The ordinary Bondi-Metzner-Sachs (BMS) group B is the common asymptotic symmetry group of all asymptotically flat Lorentzian space-times. As such, B is the best candidate for the universal symmetry group of General Relativity. However, in studying quantum gravity, space-times with signatures other than the usual Lorentzian one, and complex space-times, are frequently considered. Generalisations of B appropriate to these other signatures have been defined earlier. Here, the generalisation B(2,2) appropriate to the ultrahyperbolic signature (+,+,-,-) is described in detail, and the irreducible unitary representations (IRs) of B(2,2) are analysed. It is proved that all induced IRs of B(2,2) arise from IRs of compact 'little groups'. These little groups, which are closed subgroups of K=SO(2)xSO(2), are classified here in detail, with particular attention paid to those of infinite order

  10. NEREUS- Network of European Regions Using Space - an initiative of regions to spread the use and understanding of space technologies across Europe

    Science.gov (United States)

    Ayazi, Roya

    2013-04-01

    contributed substantially to get an idea about the regional situation and existing activities and player. NEREUS wishes to stimulate regional stakeholder to develop space applications in different domains and take measures to participate in European space programs. In this context the dialogue with end-user, in particular local and regional authorities is in the centre. To enhance the exchange between both and bring space uses in concrete administrative dossiers, NEREUS organizes together with its member regions thematic Workshops (WS), e.g. EGNOS/Galileo uses for maritime/marine purposes during which service provider discussed with harbour authorities and the policy and administrative level. The NEREUS-member region Lombardy region started to explore the opportunities of space uses for agriculture and discussed it with different stakeholder. For 2013 three thematic WS are planned (Maritime purposes, Civil Emergencies, Agriculture) with the NEREUS-network community and other partners. The NEREUS CET (Communication, Education and Training) Working Group, one of five NEREUS Working Groups, is another forum of the network that contributes to the spread of knowledge about space and its opportunities also at a broader societal scale. This group is co-chaired by Martina Hilger from Bremen and Michel Bousquet from Midi/P. Stimulating the up-take of space related studies and careers among young people in Europe is an important part for widening the understanding of space uses at citizen level. Only if Europe has a well educated and highly skilled work force will it be possible to exploit the potential of space uses and get the political support from citizen. The CET Working Group was established in 2009 and has since then been an active forum for discussion and exchange. Communicating and networking space related education at universities and other relevant organisations (if appropriate in cooperation with industry) in the NEREUS regions have been in the centre of the activities and

  11. Adjusted NIEL calculations for estimating proton-induced degradation of GaInP/GaAs/Ge space solar cells

    International Nuclear Information System (INIS)

    Lu Ming; Wang Rong; Liu Yunhong; Hu Wentao; Feng Zhao; Han Zhaolei

    2011-01-01

    The non-ionizing energy loss (NIEL) values for protons in solar cells should be modified by taking into account the distribution of the Bragg damage peak in the active region to calculate the corresponding displacement damage dose. In this paper, based upon a thin target approximation, a new approach is presented to modify NIEL values for protons on a GaAs sub-cell. Adjusted NIEL values can be used to estimate the degradation induced by protons on GaInP/GaAs/Ge triple-junction space solar cells.

  12. Fluid management in space construction

    Science.gov (United States)

    Snyder, Howard

    1989-01-01

    The low-g fluids management group with the Center for Space Construction is engaged in active research on the following topics: gauging; venting; controlling contamination; sloshing; transfer; acquisition; and two-phase flow. Our basic understanding of each of these topics at present is inadequate to design space structures optimally. A brief report is presented on each topic showing the present status, recent accomplishings by our group and our plans for future research. Reports are presented in graphic and outline form.

  13. Immunoglobulin G antibody reactivity to a group A Plasmodium falciparum erythrocyte membrane protein 1 and protection from P. falciparum malaria

    DEFF Research Database (Denmark)

    Magistrado, Pamela A; Lusingu, John; Vestergaard, Lasse S

    2007-01-01

    where P. falciparum is endemic, parasites causing severe malaria and malaria in young children with limited immunity tend to express semiconserved PfEMP1 molecules encoded by group A var genes. Here we investigated antibody responses of Tanzanians who were 0 to 19 years old to PF11_0008, a group A Pf...

  14. Space qualification of an automotive microcontroller for the DREAMS-P/H pressure and humidity instrument on board the ExoMars 2016 Schiaparelli lander

    Science.gov (United States)

    Nikkanen, T.; Schmidt, W.; Harri, A.-M.; Genzer, M.; Hieta, M.; Haukka, H.; Kemppinen, O.

    2015-10-01

    Finnish Meteorological Institute (FMI) has developed a novel kind of pressure and humidity instrument for the Schiaparelli Mars lander, which is a part of the ExoMars 2016 mission of the European Space Agency (ESA) [1]. The DREAMS-P pressure instrument and DREAMS-H humidity instrument are part of the DREAMS science package on board the lander. DREAMS-P (seen in Fig. 1 and DREAMS-H were evolved from earlier planetary pressure and humidity instrument designs by FMI with a completely redesigned control and data unit. Instead of using the conventional approach of utilizing a space grade processor component, a commercial off the shelf microcontroller was selected for handling the pressure and humidity measurements. The new controller is based on the Freescale MC9S12XEP100 16-bit automotive microcontroller. Coordinated by FMI, a batch of these microcontroller units (MCUs) went through a custom qualification process in order to accept the component for spaceflight on board a Mars lander.

  15. Systemic effects of chronic obstructive pulmonary disease in young-old adults’ life-space mobility

    Directory of Open Access Journals (Sweden)

    Garcia IFF

    2017-09-01

    Full Text Available Isabel Fialho Fontenele Garcia,1 Carina Tiemi Tiuganji,1 Maria do Socorro Morais Pereira Simões,2 Ilka Lopes Santoro,3 Adriana Claudia Lunardi1,2 1Master’s and Doctoral Programs in Physical Therapy, Universidade Cidade de São Paulo, 2Department of Physical Therapy, School of Medicine, University of Sao Paulo, 3Respiratory Division, Pulmonary Rehabilitation Center, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil Purpose: The objective was to assess whether dyspnea, peripheral muscle strength and the level of physical activity are correlated with life-space mobility of older adults with COPD.Patients and methods: Sixty patients over 60 years of age (40 in the COPD group and 20 in the control group were included. All patients were evaluated for lung function (spirometry, life-space mobility (University of Alabama at Birmingham Study of Aging Life-Space Assessment, dyspnea severity (Modified Dyspnea Index, peripheral muscle strength (handgrip dynamometer, level of physical activity and number of daily steps (accelerometry. Groups were compared using unpaired t-test. Pearson’s correlation was used to test the association between variables.Results: Life-space mobility (60.41±16.93 vs 71.07±16.28 points, dyspnea (8 [7–9] vs 11 [10–11] points, peripheral muscle strength (75.16±14.89 vs 75.50±15.13 mmHg, number of daily steps (4,865.4±2,193.3 vs 6,146.8±2,376.4 steps, and time spent in moderate to vigorous activity (197.27±146.47 vs 280.05±168.95 minutes were lower among COPD group compared to control group (p<0.05. The difference was associated with the lower mobility of COPD group in the neighborhood.Conclusion: Life-space mobility is decreased in young-old adults with COPD, especially at the neighborhood level. This impairment is associated to higher dyspnea, peripheral muscle weakness and the reduced level of physical activity. Keywords: COPD, elderly, mobility limitation, dyspnea, muscular

  16. Synthesis, Structures, and Electrochemistry of Group 6 Aminocarbenes with a P -Chelating 1''-(Diphenylphosphino)ferrocenyl Substituent

    Czech Academy of Sciences Publication Activity Database

    Meca, L.; Dvořák, D.; Ludvík, Jiří; Císařová, I.; Štěpnička, P.

    2004-01-01

    Roč. 23, č. 10 (2004), s. 2541-2551 ISSN 0276-7333 R&D Projects: GA ČR GA203/04/0487; GA ČR GA203/99/M037; GA ČR GP203/01/P002 Institutional research plan: CEZ:AV0Z4040901 Keywords : synthesis * electrochemistry of group 6 * chelating Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 3.196, year: 2004

  17. Guidance methods in psychological «spaces» of self-determination

    Directory of Open Access Journals (Sweden)

    Nikolai S. Prjazhnikov

    2017-09-01

    Full Text Available Self-determination is deemed as search and continuous refinement of the meaning of the future life. The paper discusses various options for self-determination, i.e. professional, personal, social, and other ones. Self-determination means making a certain choice. This may be career choice («career self-determination», choice of a moral position («personal self-determination», choice of one’s position in society associated with image and style of life, status in various social groups («social self-determination», choice of options («Leisure selfdetermination», or even choice of relationship type («family self-determination», etc. The generalized options and methods of orientation in various «space» of self-determination are highlighted. The psychological «spaces» are regarded as a metaphor that reflects and arranges a certain field of search for the meanings of self-determination. Each «space» is constructed according to a certain principle based on certain criteria. Psychological «space» may be determined as diverse, and in this set of self-determining personality one must be able to navigate. There are main groups of psychological «space» including the typology of options for planning life and career, the typology of work activity, the typology of professions. It is important for self-determination to define the future professional activity. Various methods are presented that allow a person to get a career orientation in complex «space» of career and life choices. Particular attention is paid to self-determination of children in adolescence. Various modern approaches in career guidance and P.Ya. Galperin’s career «orientation» principles are drawn to a concordance.

  18. Expression, purification and preliminary diffraction studies of PhnP

    International Nuclear Information System (INIS)

    Podzelinska, Kateryna; He, Shumei; Soares, Alexei; Zechel, David; Hove-Jensen, Bjarne; Jia, Zongchao

    2008-01-01

    PhnP, a member of the C—P lyase pathway, was crystallized by the sitting-drop vapour-diffusion method and the initial diffraction-pattern analysis is reported. PhnP belongs to a 14-gene operon that supports the growth of Escherichia coli on alkylphosphonates as a sole source of phosphorus; however, the exact biochemistry of phosphonate degradation by this pathway is poorly understood. The protein was recombinantly expressed in Escherichia coli and purified to homogeneity. Sitting-drop vapour diffusion in combination with microseeding was used to obtain crystals that were suitable for X-ray diffraction. Data were collected to 1.3 Å and the crystals belonged to space group C2, with unit-cell parameters a = 111.65, b = 75.41, c = 83.23 Å, α = γ = 90, β = 126.3°

  19. Flat slices in Minkowski space

    Science.gov (United States)

    Murchadha, Niall Ó.; Xie, Naqing

    2015-03-01

    Minkowski space, flat spacetime, with a distance measure in natural units of d{{s}2}=-d{{t}2}+d{{x}2}+d{{y}2}+d{{z}2}, or equivalently, with spacetime metric diag(-1, +1, +1, +1), is recognized as a fundamental arena for physics. The Poincaré group, the set of all rigid spacetime rotations and translations, is the symmetry group of Minkowski space. The action of this group preserves the form of the spacetime metric. Each t = constant slice of each preferred coordinate system is flat. We show that there are also nontrivial non-singular representations of Minkowski space with complete flat slices. If the embedding of the flat slices decays appropriately at infinity, the only flat slices are the standard ones. However, if we remove the decay condition, we find non-trivial flat slices with non-vanishing extrinsic curvature. We write out explicitly the coordinate transformation to a frame with such slices.

  20. Spin Gauge Theory of Gravity in Clifford Space

    International Nuclear Information System (INIS)

    Pavsic, Matej

    2006-01-01

    A theory in which 16-dimensional curved Clifford space (C-space) provides a realization of Kaluza-Klein theory is investigated. No extra dimensions of spacetime are needed: 'extra dimensions' are in C-space. We explore the spin gauge theory in C-space and show that the generalized spin connection contains the usual 4-dimensional gravity and Yang-Mills fields of the U(1) x SU(2) x SU(3) gauge group. The representation space for the latter group is provided by 16-component generalized spinors composed of four usual 4-component spinors, defined geometrically as the members of four independent minimal left ideals of Clifford algebra