Digital Morphometrics: A New Upper Airway Phenotyping Paradigm in OSA.

Science.gov (United States)

Schwab, Richard J; Leinwand, Sarah E; Bearn, Cary B; Maislin, Greg; Rao, Ramya Bhat; Nagaraja, Adithya; Wang, Stephen; Keenan, Brendan T

2017-08-01

OSA is associated with changes in pharyngeal anatomy. The goal of this study was to objectively and reproducibly quantify pharyngeal anatomy by using digital morphometrics based on a laser ruler and to assess differences between subjects with OSA and control subjects and associations with the apnea-hypopnea index (AHI). To the best of our knowledge, this study is the first to use digital morphometrics to quantify intraoral risk factors for OSA. Digital photographs were obtained by using an intraoral laser ruler and digital camera in 318 control subjects (mean AHI, 4.2 events/hour) and 542 subjects with OSA (mean AHI, 39.2 events/hour). The digital morphometric paradigm was validated and reproducible over time and camera distances. A larger modified Mallampati score and having a nonvisible airway were associated with a higher AHI, both unadjusted (P digital morphometrics is an accurate, high-throughput, and noninvasive technique to identify anatomic OSA risk factors. Morphometrics may also provide a more reproducible and standardized measurement of the Mallampati score. Digital morphometrics represent an efficient and cost-effective method of examining intraoral crowding and tongue size when examining large populations, genetics, or screening for OSA. Copyright © 2017 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.

Uus äriseadustik lihtsustab osaühingu asutamist ja juhtimist / Karina Paatsi

Index Scriptorium Estoniae

Paatsi, Karina

2010-01-01

Osaühingut puudutavatest äriseadustiku muudatustest (sissemakseta osaühing, osa võõrandamise võimaluste laienemine, juhatuse liikme valimine tähtajatuks perioodiks, nõukogu nõude kaotamine, elukoha piirangu kaotamine, mitterahalise sissemakse hindamine, reservkapitali nõude kadumine)

Driving simulator and neuropsychological [corrected] testing in OSAS before and under CPAP therapy.

Science.gov (United States)

Orth, M; Duchna, H-W; Leidag, M; Widdig, W; Rasche, K; Bauer, T T; Walther, J W; de Zeeuw, J; Malin, J-P; Schultze-Werninghaus, G; Kotterba, S

2005-11-01

Patients with obstructive sleep apnoea syndrome (OSAS) have an increased car accident rate. Investigations on accident frequency are based on case history, insurance reports and driving simulator studies. The present study combines neuropsychological testing of different attention aspects engaged in driving a car and driving simulation to evaluate a suitable instrument for assessing therapeutic effects of continuous positive airway pressure (CPAP). Driving simulator investigation and neuropsychological testing of alertness, vigilance and divided attention were performed in 31 patients with polysomnographically confirmed OSAS (apnoea-hypopnoea index 24.8+/-21.5.h(-1)) before, and 2 and 42 days after initiation of CPAP. Divided attention and alertness improved significantly during CPAP, whereas vigilance remained unchanged. However, accident frequency (OSAS before therapy: 2.7+/-2.0; 2 days after CPAP: 1.5+/-1.4; 42 days after CPAP: 0.9+/-1.3) and frequency of concentration faults (OSAS before therapy: 12.4+/-5.1; 2 days after CPAP: 6.5+/-3.9; 42 days after CPAP: 4.9+/-3.3) decreased in the simulated driving situation after 2 and 42 days of therapy. There was no relation between accident frequency, concentration faults and daytime sleepiness, as measured by the Epworth Sleepiness Scale, and polysomnographic or neuropsychological findings, respectively. In conclusion, the present results suggest that driving simulation is a possible benchmark parameter of driving performance in obstructive sleep apnoea syndrome patients.

Preparation And Physicochemical Properties of Octenyl Succinic Anhydride (OSA) Modified Sago Starch

International Nuclear Information System (INIS)

Nur Farhana Zainal Abiddin; Anida Yusoff; Noorlaila Ahmad

2016-01-01

Starch from sago (Metroxylon sagu) was esterified with octenyl succinic anhydride (OSA) in order to regulate its shortcoming by adding amphiphilic properties. The objective of this work is to determine the physicochemical properties of native sago and OSA sago starches. The OSA sago starch was produced according to the optimum condition generated via response surface methodology (RSM) with 5.00 % OSA at pH 7.20 and a reaction time of 9.65 hours. The esterified sago starch gives a degree of substitution (DS) value of 0.012. The physicochemical properties of OSA sago starch was determined by measuring the amylose content, laser diffraction particle size analyzer, scanning electron microscopy (SEM) and Fourier transform infrared (FT-IR). The amylose content for OSA sago starch was found to be reduced after esterification reaction. The particle size of OSA sago starch was found to increase significantly (p<0.05) compared to their native starches. Scanning electron microscopy (SEM) revealed that OSA starch developed slightly rough surface and their edges lost some definition. FT-IR spectroscopy shows that there was appearance of new absorption correspond to ester carbonyl group (1717 cm -1 ) and carboxylate RCOO- (1569 cm -1 ). This study showed that the physicochemical properties of modified starches were influenced not only by DS but also on the botanical origin of the starches. (author)

Age, gender, neck circumference, and Epworth sleepiness scale do not predict obstructive sleep apnea (OSA in moderate to severe chronic obstructive pulmonary disease (COPD: The challenge to predict OSA in advanced COPD.

Directory of Open Access Journals (Sweden)

Xavier Soler

Full Text Available The combination of chronic obstructive pulmonary disease (COPD and obstructive sleep apnea (OSA is associated with substantial morbidity and mortality. We hypothesized that predictors of OSA among patients with COPD may be distinct from OSA in the general population. Therefore, we investigated associations between traditional OSA risk factors (e.g. age, and sleep questionnaires [e.g. Epworth Sleepiness Scale] in 44 patients with advanced COPD. As a second aim we proposed a pilot, simplified screening test for OSA in patients with COPD. In a prospective, observational study of patients enrolled in the UCSD Pulmonary Rehabilitation Program we collected baseline characteristics, cardiovascular events (e.g. atrial fibrillation, and sleep questionnaires [e.g. Pittsburgh Sleep Quality Index (PSQI]. For the pilot questionnaire, a BMI ≥25 kg/m2 and the presence of cardiovascular disease were used to construct the pilot screening test. Male: 59%; OSA 66%. FEV1 (mean ± SD = 41.0±18.2% pred., FEV1/FVC = 41.5±12.7%]. Male gender, older age, and large neck circumference were not associated with OSA. Also, Epworth Sleepiness Scale and the STOP-Bang questionnaire were not associated with OSA in univariate logistic regression. In contrast, BMI ≥25 kg/m2 (OR = 3.94, p = 0.04 and diagnosis of cardiovascular disease (OR = 5.06, p = 0.03 were significantly associated with OSA [area under curve (AUC = 0.74]. The pilot COPD-OSA test (OR = 5.28, p = 0.05 and STOP-Bang questionnaire (OR = 5.13, p = 0.03 were both associated with OSA in Receiver Operating Characteristics (ROC analysis. The COPD-OSA test had the best AUC (0.74, sensitivity (92%, and specificity (83%. A ten-fold cross-validation validated our results. We found that traditional OSA predictors (e.g. gender, Epworth score did not perform well in patients with more advanced COPD. Our pilot test may be an easy to implement instrument to screen for OSA. However, a larger validation study is necessary

Age, gender, neck circumference, and Epworth sleepiness scale do not predict obstructive sleep apnea (OSA) in moderate to severe chronic obstructive pulmonary disease (COPD): The challenge to predict OSA in advanced COPD.

Science.gov (United States)

Soler, Xavier; Liao, Shu-Yi; Marin, Jose Maria; Lorenzi-Filho, Geraldo; Jen, Rachel; DeYoung, Pamela; Owens, Robert L; Ries, Andrew L; Malhotra, Atul

2017-01-01

The combination of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) is associated with substantial morbidity and mortality. We hypothesized that predictors of OSA among patients with COPD may be distinct from OSA in the general population. Therefore, we investigated associations between traditional OSA risk factors (e.g. age), and sleep questionnaires [e.g. Epworth Sleepiness Scale] in 44 patients with advanced COPD. As a second aim we proposed a pilot, simplified screening test for OSA in patients with COPD. In a prospective, observational study of patients enrolled in the UCSD Pulmonary Rehabilitation Program we collected baseline characteristics, cardiovascular events (e.g. atrial fibrillation), and sleep questionnaires [e.g. Pittsburgh Sleep Quality Index (PSQI)]. For the pilot questionnaire, a BMI ≥25 kg/m2 and the presence of cardiovascular disease were used to construct the pilot screening test. Male: 59%; OSA 66%. FEV1 (mean ± SD) = 41.0±18.2% pred., FEV1/FVC = 41.5±12.7%]. Male gender, older age, and large neck circumference were not associated with OSA. Also, Epworth Sleepiness Scale and the STOP-Bang questionnaire were not associated with OSA in univariate logistic regression. In contrast, BMI ≥25 kg/m2 (OR = 3.94, p = 0.04) and diagnosis of cardiovascular disease (OR = 5.06, p = 0.03) were significantly associated with OSA [area under curve (AUC) = 0.74]. The pilot COPD-OSA test (OR = 5.28, p = 0.05) and STOP-Bang questionnaire (OR = 5.13, p = 0.03) were both associated with OSA in Receiver Operating Characteristics (ROC) analysis. The COPD-OSA test had the best AUC (0.74), sensitivity (92%), and specificity (83%). A ten-fold cross-validation validated our results. We found that traditional OSA predictors (e.g. gender, Epworth score) did not perform well in patients with more advanced COPD. Our pilot test may be an easy to implement instrument to screen for OSA. However, a larger validation study is necessary before

Remote sensing of methane with OSAS-lidar on the 2ν3 band Q-branch: Experimental proof

Science.gov (United States)

Galtier, Sandrine; Anselmo, Christophe; Welschinger, Jean-Yves; Sivignon, J. F.; Cariou, Jean-Pierre; Miffre, Alain; Rairoux, Patrick

2018-06-01

Optical sensors based on absorption spectroscopy play a central role in the detection and monitoring of atmospheric trace gases. We here present for the first time the experimental demonstration of OSAS-Lidar on the remote sensing of CH4 in the atmosphere. This new methodology, the OSAS-Lidar, couples the Optical Similitude Absorption Spectroscopy (OSAS) methodology with a light detection and ranging device. It is based on the differential absorption of spectrally integrated signals following Beer Lambert-Bouguer law, which are range-resolved. Its novelty originates from the use of broadband laser spectroscopy and from the mathematical approach used to retrieve the trace gas concentration. We previously applied the OSAS methodology in laboratory on the 2ν3 methane absorption band, centered at the 1665 nm wavelength and demonstrated that the OSAS-methodology is almost independent from atmospheric temperature and pressure. In this paper, we achieve an OSAS-Lidar device capable of observing large concentrations of CH4 released from a methane source directly into the atmosphere. Comparison with a standard in-situ measurement device shows that the path-integrated concentrations retrieved from OSAS-Lidar methodology exhibit sufficient sensitivity (2 000 ppm m) and observational time resolution (1 s) to remotely sense methane leaks in the atmosphere. The coupling of OSAS-lidar with a wind measurement device opens the way to monitor time-resolved methane flux emissions, which is important in regards to future climate mitigation involving regional reduction of CH4 flux emissions.

Quality of Life in Youth With Obstructive Sleep Apnea Syndrome (OSAS) Treated With Continuous Positive Airway Pressure (CPAP) Therapy.

Science.gov (United States)

Lynch, Mary K; Elliott, Lindsey C; Avis, Kristin T; Schwebel, David C; Goodin, Burel R

2017-05-30

Improvement is sought for youth with obstructive sleep apnea syndrome (OSAS) who have poor quality of life (QoL), which resolves somewhat following treatment. One mitigating factor in improved QoL following treatment may be adherence to the CPAP protocol, which presents a barrier to most youth. This study explored relations between CPAP adherence and QoL in youth with OSAS. We recruited 42 youth-caregiver dyads in which youth between the ages of 8 and 16 years were diagnosed with OSAS and required CPAP use as part of their treatment plan. Following diagnosis of OSAS requiring treatment with CPAP therapy, caregivers completed baseline measures of OSAS-specific QoL. The OSAS-specific QoL domains assessed included sleep disturbance, physical symptoms, emotional distress, daytime function, and caregiver concern. Families received routine CPAP care for three months, after which caregivers again completed measures of OSAS-specific QoL. Adherence data were collected from smartcards within the CPAP machine after three months of treatment. Fifteen youth were adherent to CPAP therapy and 10 were not adherent. CPAP-adherent youth demonstrated significant changes in two domains of OSAS-specific QoL when compared to nonadherent youth: decreased sleep disturbance and decreased caregiver concern. CPAP adherence appears to be associated with positive changes in OSAS-specific QoL domains. It will be important for future research and clinical work to examine strategies for improving CPAP adherence in youth with OSAS.

Analysis of OSAS incidence and influential factors in middle-aged and elderly patients with hypertension.

Science.gov (United States)

Wang, Shuang; Niu, Xinqing; Zhang, Peipei; Su, Dexing; Zhang, Jing; Liu, Wei

2018-04-24

To investigate the detection rate and influencing factors of obstructive sleep apnea syndrome (OSAS) in middle-aged and elderly patients with hypertension. A total of 440 patients with hypertension were selected as the research objects, all of them participated in the Berlin questionnaire survey, and the polysomnography (PSG) was performed on the patients with a high risk of OSAS. The detection rate of OSAS was analyzed, the clinical data between non-OSAS group and OSAS group were compared and stepwise linear regression and Logistic regression were used to analyze the related influencing factors to apnea hyponea index (AHI) and OSAS in hypertensive patients. A total of 235 patients completed PSG and 196 patients were diagnosed as OSAS with the detection rate of 83.40%. The detection rate of OSAS in male patients was higher than that in females (89.04% vs.74.16%, x²=8.025, P=0.006). The detection rates of OSAS in normal BMI group, overweight group and obesity group were 56.52%, 92.37% and 100%, respectively (x²=36.438, P<0.001). The detection rates of OSAS in normal waistline group and central obesity group were 74.42% and 88.59% (x²=7.539, P=0.016). The detection rates of OSAS in grade1, grade 2 and grade 3 hypertension groups were 57.47%, 98.23% and 100%, respectively (x²=44.623, P<0.001). BMI, systolic blood pressure (SBP), diastolic blood pressure (DBP), low density lipoprotein (LDL) and waist circumference of OSAS group were all higher than those in non-OSAS group (P<0.05). BMI, SBP and DBP were positively correlated with AHI (p<0.05), which were independent risk factors of OSAS [OR value (95%CI) = 2.548 (1.449-4.327), 1.342 (1.214-1.965) and 1.169 (1.025-1.622), respectively, P<0.05]. The incidence of OSAS in middle-aged and elderly patients with hypertension is high. High BMI, SBP, and DBP are independent risk factors of OSAS.

OSA screening with the pediatric sleep questionnaire for adolescents undergoing bariatric surgery in teen-LABS.

Science.gov (United States)

Ishman, Stacey; Heubi, Christine; Jenkins, Todd; Michalsky, Marc; Simakajornboon, Narong; Inge, Thomas

2016-11-01

Obstructive sleep apnea (OSA) is reported in 70% of adolescents who present for bariatric surgery. The Pediatric Sleep Questionnaire (PSQ) was developed to identify children at risk for OSA but is not validated in adolescents with obesity. The aims of this study were: (1) to assess validity of the PSQ to detect OSA and (2) to determine the correlation between anthropometric and polysomnography measurements. A cross-sectional assessment of Teen-Longitudinal Assessment of Bariatric Surgery participants at high risk for OSA was performed. Participants completed an overnight polysomnography, and caregivers completed the PSQ. Forty-five participants (84% female, 78% Caucasian, mean age = 16.7 ± 1.5 years) were evaluated. Mean BMI was 51.3 ± 7.7 kg/m 2 and mean obstructive apnea-hypopnea index (oAHI) was 6.1 ± 5.9 events/h. For diagnosis of OSA (oAHI ≥5), the total PSQ score sensitivity, specificity, and positive predictive value (PPV) were 86%, 38%, and 55%, respectively. For snoring >50% of the time, PPV was 84%, sensitivity was 64%, and specificity was 43%. Sagittal abdominal diameter correlated with oAHI and oxygen saturation nadir (ρ = 0.34, P = 0.027), whereas BMI, neck, and waist circumference correlated with neither. The PSQ demonstrated low specificity, and PPV and the question regarding snoring >50% of the time did not effectively identify OSA. Sagittal abdominal diameter correlated with oAHI and oxygen saturation nadir. © 2016 The Obesity Society.

Predicting uptake of continuous positive airway pressure (CPAP) therapy in obstructive sleep apnoea (OSA)

DEFF Research Database (Denmark)

Skinner, Timothy; McNeil, Lindsay; Olaithe, Michelle

2013-01-01

diagnosed with OSA. Epworth sleepiness scale (ESS), Fatigue Severity Scale, Depression Anxiety Stress Scale and Illness Perception Questionnaire-Revised (IPQ-R) were administered at time of sleep study. These, patient demographics and sleep study variables were used to determine factors predicting patient......Purpose: Obstructive sleep apnoea (OSA) is a common disorder, for which continuous positive airway pressure (CPAP) therapy is a standard treatment. Despite its well-established efficacy, many patients choose not to initiate CPAP treatment. The present study investigated the degree to which...

The effect of CPAP treatment on EEG of OSAS patients.

Science.gov (United States)

Zhang, Cheng; Lv, Jun; Zhou, Junhong; Su, Li; Feng, Liping; Ma, Jing; Wang, Guangfa; Zhang, Jue

2015-12-01

Continuous positive airway pressure (CPAP) is currently the most effective treatment method for obstructive sleep apnea syndrome (OSAS). The purpose of this study was to compare the sleep electroencephalogram (EEG) changes before and after the application of CPAP to OSAS patients. A retrospective study was conducted and 45 sequential patients who received both polysomnography (PSG) and CPAP titration were included. The raw data of sleep EEG were extracted and analyzed by engineers using two main factors: fractal dimension (FD) and the zero-crossing rate of detrended FD (zDFD). FD was an effective indicator reflecting the EEG complexity and zDFD was useful to reflect the variability of the EEG complexity. The FD and zDFD indexes of sleep EEG of 45 OSAS patients before and after CPAP titration were analyzed. The age of 45 OSAS patients was 52.7 ± 5.6 years old and the patients include 12 females and 33 males. After CPAP treatment, FD of EEG in non-rapid eye movement (NREM) sleep decreased significantly (P CPAP therapy (P CPAP therapy had a significant influence on sleep EEG in patients with OSAHS, which lead to a more stable EEG pattern. This may be one of the mechanisms that CPAP could improve sleep quality and brain function of OSAS patients.

online-osa festivalil / Tiia Johannson

Index Scriptorium Estoniae

Johannson, Tiia, 1965-2002

1998-01-01

Prantsusmaa, Balti ja Põhjamaade video ja uue meedia festival "offline@online" Eesti Kunstiakadeemias. Ka eesti netikunstist, festivali korralduslikust küljest, tulevikuplaanidest. Erilist äramärkimist leidis sloveenia kunstniku Vuk Cosici töö "ascii history of moving images", online-presentatsioonide osas Lev Manovichi teoreetiline loeng "Uue meedia keel". Aadress festivali netikunsti vaatamiseks

Evaluation of degree of lacunar infarction and carotid atherosclerosis in patients with different severity of OSAS

Directory of Open Access Journals (Sweden)

Ming Du

2016-07-01

Full Text Available Objective: To assess the degree of lacunar infarction and carotid atherosclerosis in patients with different severity of obstructive sleep apnea syndrome (OSAS. Methods: A total of 198 patients with OSAS were retrospectively studied from case information and test results, and were divided into mild group 84 cases, medium group 70 cases and severe group 44 cases according to apnea-hypopnea index (AHI, and 176 cases of non-OSAS people who received physical examination in our hospital during the same period were selected as healthy control group. Differences in the values of serum lacunar infarction-related indexes, blood viscosity and hemocyte-related indexes, carotid structure and function parameters, serum arteriosclerosis-related indexes and so on were compared among groups. Results: t-PA value of healthy control group was higher than those of OSAS group while vWF, PAI-1 and Fg values were lower than those of OSAS group (P<0.05, and with the increase of OSAS severity, t-PA value decreased while vWF, PAI-1 and Fg values increased (P<0.05; blood viscosity, Hct, PDW, RDW and EFR values of healthy control group were lower than those of OSAS group (P<0.05, and with the increase of OSAS severity, blood viscosity, Hct, PDW, RDW and EFR values increased (P<0.05; FMD, NID and DC values of healthy control group were higher than those of OSAS group while Dis, CC and PWV values were lower than those of OSAS group (P<0.05, and with the increase of OSAS severity, FMD, NID and DC values decreased while Dis, CC and PWV values increased (P<0.05; blood uric acid and EF-1 values of healthy control group were lower than those of OSAS group while CGRP and fetuin A levels were higher than those of OSAS group (P<0.05, and with the aggravation of OSAS, blood uric acid and EF-1 levels increased while CGRP and fetuin A levels decreased, and differences among groups were significant (P<0.05. Conclusions: With the aggravation of OSAS, patients’ microcirculation

The USC-OSA-EPS section activities in optics

Science.gov (United States)

Aymerich, María.; Cambronero-López, Ferran; Aragón, Ángel L.; Delgado, Tamara; Blanco, Manuel; Gómez Varela, Ana I.; Gargallo, Ana; Williamson, Sandra; Amorín, Adán.; Sánchez-García, Ángel; Bao-Varela, Carmen; Flores-Arias, M. Teresa

2017-08-01

The USC-OSA Student Chapter and USC-EPS Young Minds Section is a group financed by The Optical Society (OSA) and the European Physical Society (EPS). It is formed by PhD and degree students from the Universidade de Santiago de Compostela (USC) and one supervisor of the Faculty of Physics. Its main goal is to promote and diffuse Optics in the society. For this purpose, the group carries out several activities in the academic and non-academic community. The group is also committed to the professional development of our members and motivates the exposition of our work into the scientific community.

Obstructive sleep apnea (OSA): a complication of acute infectious mononucleosis infection in a child.

Science.gov (United States)

Cheng, Jeffrey

2014-03-01

Independently, obstructive sleep apnea (OSA) and infectious mononucleosis are not uncommon in the pediatric population, but acute onset of OSA, as a respiratory complication in the setting of acute EBV infection is extremely uncommon. Previous reports of this clinical entity are sparse and from nearly two decades ago. Urgent adenotonsillectomy was commonly advocated. This complication may be managed medically with systemic corticosteroids and non-invasive continuous positive airway pressure (CPAP), and a case is presented to highlight an updated management approach to this rarely encountered clinical problem in children. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Assessment of the Depression, Anxiety, and Stress Scale (DASS-21) in untreated obstructive sleep apnea (OSA).

Science.gov (United States)

Nanthakumar, Shenooka; Bucks, Romola S; Skinner, Timothy C; Starkstein, Sergio; Hillman, David; James, Alan; Hunter, Michael

2017-10-01

The assessment of depression in obstructive sleep apnea (OSA) is confounded by symptom overlap. The Depression, Anxiety, and Stress Scale-short form (DASS-21) is a commonly used measure of negative affect, but it not known whether the DASS-21 is suitable for use in an OSA sample. This study compared the fit of Lovibond and Lovibond's (1995) correlated 3-factor structure of the DASS-21 and measurement invariance between a non-OSA and an OSA sample using confirmatory factor analysis. As measurement invariance was not found, to determine the source of non-invariance differential item functioning (DIF) was examined using dMACS. The correlated 3-factor structure (with correlated errors) of the DASS-21 was a better fit in the non-OSA sample. dMACS indicated that there was a degree of DIF for each of the subscales, especially for the Anxiety subscale, in which 2 symptoms (that are also physiological symptoms of OSA) produced lower severity scores in the OSA sample compared with the non-OSA sample. However, the degree of DIF for each of the subscales is not sufficient to cause concern when using the DASS-21; therefore, the total DASS-21 is suitable for use in an OSA sample. Interestingly, the impact of symptom overlap in anxiety symptoms may be reducing anxiety scores because of DIF, which contrasts with the proposed effect of symptom overlap in depression, where it leads to the inflation of depression scores in OSA. This deserves greater consideration in relation to OSA and other clinical disorders or chronic illness conditions with different patterns of overlapping symptoms. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Asthma Control and Its Relationship with Obstructive Sleep Apnea (OSA in Older Adults

Directory of Open Access Journals (Sweden)

Mihaela Teodorescu

2013-01-01

Full Text Available Background/Objectives. Asthma in older individuals is poorly understood. We aimed to characterize the older asthma phenotype and test its association with obstructive sleep apnea (OSA. Design. Cross-sectional. Setting. Pulmonary and Asthma/Allergy clinics. Participants. 659 asthma subjects aged 18–59 years (younger and 154 aged 60–75 (older. Measurements. Sleep Apnea scale of Sleep Disorders Questionnaire (SA-SDQ, asthma severity step (1–4, severe if step 3 or 4, established OSA diagnosis, continuous positive airway pressure (CPAP use, and comorbidities. Results. Older versus younger had worse control, as assessed by asthma step, lung function, and inhaled corticosteroid use. Among older subjects, after controlling for known asthma aggravators, OSA diagnosis was the only factor robustly associated with severe asthma: on average, OSA was associated with nearly 7 times greater likelihood of severe asthma in an older individual (OR=6.67. This relationship was of greater magnitude than in younger subjects (OR=2.16. CPAP use attenuated the likelihood of severe asthma in older subjects by 91% (P=0.005, much more than in the younger asthmatics. Conclusion. Diagnosed OSA increases the risk for worse asthma control in older patients, while CPAP therapy may have greater impact on asthma outcomes. Unrecognized OSA may be a reason for poor asthma control, particularly among older patients.

Obstructive Sleep Apnea Syndrome (OSAS, metabolic syndrome and mental health in small enterprise workers. feasibility of an Action for Health.

Directory of Open Access Journals (Sweden)

Sergio Garbarino

Full Text Available OBJECTIVE: To determine the frequency of obstructive sleep apnea syndrome (OSAS, metabolic syndrome and common mental disorders in the working population of 11 small enterprises and the feasibility of a program of action for health. METHOD: The clinical risk of OSAS, the prevalence of metabolic syndrome, and the level of psychological disorders were assessed during routine medical examination at the workplace in 2012. The response to medical advice was assessed in 2013. RESULTS: 12.3% of the workers were suspected of being affected by OSAS. One or more components of metabolic syndrome were present in 24.5% of cases. OSAS in "healthy" workers was significantly associated with the presence of one or more components of metabolic syndrome (OR = 3.83; 95%CI 1.45-10.13 and with a psychological disorders score in the highest quartile (OR = 4.67; 95%CI = 1.72-12.64. Workers with suspected OSAS were reluctant to follow advice about undergoing further tests under the NHS. However, in some cases, confirmation of the OSAS diagnosis and subsequent treatment led to an improvement in metabolic condition. CONCLUSION: Although participation in treatment was limited, anecdotal cases support the idea that prevention of obstructive sleep apnea in the workplace might be useful for workers' health.

The use of endomarketing in credit unions: a case study of the UFVCredi and the Unicred-Viçosa O emprego do endomarketing em cooperativas de crédito: estudo de caso da UFV-Credi e da Unicred-Viçosa

Directory of Open Access Journals (Sweden)

Henrique Lopes Dornelas

2002-11-01

Full Text Available Endomarketing can be considered as a group of activities concerned with the internal aspects of the organization, whose purpose is to value the human being. In order to become competitive, the Credit Unions should adopt Endomarketing strategies that combine motivation, training and communication elements. The purpose of the present work was to verify how the Credit Union of the Workers of the Federal University of Viçosa Ltd. / UFV-CREDI and the Credit Union of the Doctors and Health-related Professionals of Viçosa Ltd. – UNICRED/VIÇOSA – MG are using the tools offered by Endomarketing. In the methodology, a study concerning the Endomarketing and the Credit Unions war carried out. After that, the employees and the members of the Credit Unions were asked to answer a questionnaire. After the analysis of the obtained data, it was concluded that UFV-CREDI and UNICRED/VIÇOSA-MG have effectively reached their objectives because their Endomarketing strategies have presented positive results, making it possible for them to get new members as well as to keep their members and employees motivated and satisfied with the products and services offered by the Credit Unions.O Endomarketing pode ser conceituado como um conjunto de atividades voltadas para o interior da organização, cuja finalidade é valorizar o ser humano. Para que as cooperativas de crédito sejam competitivas, elas devem adotar estratégias de Endomarketing, que combinem elementos de motivação, treinamento e comunicação. Procurou-se com o presente estudo, verificar como a Cooperativa de Economia e Crédito Mútuo dos Servidores da Universidade Federal de Viçosa – LTDA / UFV-CREDI e a Cooperativa de Economia e Crédito Mútuo dos Médicos e demais Profissionais da Saúde de Viçosa Ltda – UNICRED/VIÇOSA-MG estão utilizando as ferramentas oferecidas pelo Endomarketing. Na metodologia foi realizado um estudo acerca do Endomarketing e das cooperativas de crédito, para

The effect of allergic rhinitis on the degree of stress, fatigue and quality of life in OSA patients.

Science.gov (United States)

Park, Cheol Eon; Shin, Seung Youp; Lee, Kun Hee; Cho, Joong Saeng; Kim, Sung Wan

2012-09-01

Both allergic rhinitis (AR) and obstructive sleep apnea (OSA) are known to increase stress and fatigue, but the result of their coexistence has not been studied. The objective of this study was to evaluate the amount of stress and fatigue when AR is combined with OSA. One hundred and twelve patients diagnosed with OSA by polysomnography were enrolled. Among them, 37 patients were diagnosed with AR by a skin prick test and symptoms (OSA-AR group) and 75 patients were classified into the OSA group since they tested negative for allergies. We evaluated the Epworth sleepiness scale (ESS), stress score, fatigue score, ability to cope with stress, and rhinosinusitis quality of life questionnaire (RQLQ) with questionnaires and statistically compared the scores of both groups. There were no significant differences in BMI and sleep parameters such as LSAT, AHI, and RERA between the two groups. However, the OSA-AR group showed a significantly higher ESS score compared to the OSA group (13.7 ± 4.7 vs. 9.3 ± 4.8). Fatigue scores were also significantly higher in the OSA-AR group than in the OSA group (39.8 ± 11.0 vs. 30.6 ± 5.4). The OSA-AR group had a significantly higher stress score (60.4 ± 18.6 vs. 51.2 ± 10.4). The ability to cope with stress was higher in the OSA group, although this difference was not statistically significant. RQLQ scores were higher in the OSA-AR group (60.2 ± 16.7 compared to 25.1 ± 13.9). In conclusion, management of allergic rhinitis is very important in treating OSA patients in order to eliminate stress and fatigue and to minimize daytime sleepiness and quality of life.

Autonomic and metabolic effects of OSA in childhood obesity.

Science.gov (United States)

Oliveira, F M; Tran, W H; Lesser, D; Bhatia, R; Ortega, R; Mittelman, S D; Keens, T G; Davidson Ward, S L; Khoo, M C

2010-01-01

This study investigates the effects of exposure to intermittent hypoxia on cardiovascular autonomic control and metabolic function in obese children with obstructive sleep apnea (OSA). Each subject underwent: (1) a polysomnography; (2) morning fasting blood samples and a subsequent FSIVGTT; (3) noninvasive measurement of respiration, arterial blood pressure, and heart rate during supine and standing postures. Assessment of adiposity was performed using a DEXA scan. From these measurements, we deduced the pertinent sleep parameters, Bergman minimal model parameters and the parameters characterizing a minimal model of cardiovascular variability. Results suggest that intermittent hypoxia in OSA contributes independently to insulin resistance and autonomic dysfunction in overweight children.

Comparative Emulsifying Properties of Octenyl Succinic Anhydride (OSA-Modified Starch: Granular Form vs Dissolved State.

Directory of Open Access Journals (Sweden)

María Matos

Full Text Available The emulsifying ability of OSA-modified and native starch in the granular form, in the dissolved state and a combination of both was compared. This study aims to understand mixed systems of particles and dissolved starch with respect to what species dominates at droplet interfaces and how stability is affected by addition of one of the species to already formed emulsions. It was possible to create emulsions with OSA-modified starch isolated from Quinoa as sole emulsifier. Similar droplet sizes were obtained with emulsions prepared at 7% (w/w oil content using OSA-modified starch in the granular form or molecularly dissolved but large differences were observed regarding stability. Pickering emulsions kept their droplet size constant after one month while emulsions formulated with OSA-modified starch dissolved exhibited coalescence. All emulsions stabilized combining OSA-modified starch in granular form and in solution showed larger mean droplet sizes with no significant differences with respect to the order of addition. These emulsions were unstable due to coalescence regarding presence of free oil. Similar results were obtained when emulsions were prepared by combining OSA-modified granules with native starch in solution. The degree of surface coverage of starch granules was much lower in presence of starch in solution which indicates that OSA-starch is more surface active in the dissolved state than in granular form, although it led to unstable systems compared to starch granule stabilized Pickering emulsions, which demonstrated to be extremely stable.

Marcadores de estrés oxidativo en placentas de gestantes añosas

Directory of Open Access Journals (Sweden)

Silvia Suárez

2007-12-01

Full Text Available Introducción: Un factor de riesgo alto ginecoobstétrico que contribuye a la morbimortalidad materna perinatal es la edad materna mayor de 35 años. Es posible que el estado oxidativo en la placenta de la gestante añosa sea mayor a la de la gestante no añosa. Objetivo: Evaluar el estado oxidativo de la placenta en gestantes mayores de 35 años. Diseño: Estudio observacional y transversal. Lugar: Hospital Nacional Docente Materno Infantil San Bartolomé y Centro de Investigación de Bioquímica y Nutrición de la Universidad Nacional Mayor de San Marcos. Material biológico: 28 placentas de gestantes de 35 años o más y 28 placentas de gestantes de menos de 35 años, obtenidas de partos vaginales a término. Intervenciones: La muestra de placenta se homogenizó al 10% con buffer fosfato 10 mM, pH 7,4, se centrifugó a 2000 rpm por 5’. Parte del sobrenadante se usó para analizar lipoperoxidación y glutatión (GSH; el sobrenadante restante fue centrifugado a 42 000 rpm por 1 hora, para medir actividad de superóxido dismutasa (SOD. Principales medidas de resultados: Estado oxidativo de placentas obtenidas de mujeres añosas y no añosas. Resultados: La actividad de la SOD y el contenido de GSH placentarios en añosas fue 43,52 U/g de tejido y 4,67 µmol/mL x 10-²; para el grupo control fueron 54,13 U/g de tejido y 6,02 µmol/mL x 10-², respectivamente; en ambos hubo significancia estadística (p < 0,05. La medición de TBARS (lipoperoxidación no mostró diferencias significativas. Conclusiones: Las placentas obtenidas de mujeres añosas muestran menor capacidad de defensa antioxidante frente a las placentas obtenidas de mujeres no añosas.

The USC-OSA Student Chapter: goals and benefits for the optics community

Science.gov (United States)

Gómez-Varela, A. I.; Gargallo, Ana; González Núñez, Héctor; Delgado-García, Tamara; Almaguer-Gómez, Citlalli; Cambronero-López, F.; Flores-Arias, M. T.

2014-07-01

The USC-OSA Student Chapter has been constituted in March 2013 by members of the University of Santiago de Compostela (USC) in Spain and sponsored by The Optical Society of America (OSA). It is formed by five graduate and one undergraduate students with the common interest in Optics and Photonics research and a professor of the USC is also involved as a faculty advisor. We decided to start this group with the aim of involving kids, precollege and undergraduate students in the world of Optics and Photonics. The activities that the USC-OSA Student Chapter members intend to realize are mainly educational tasks for the spreading of knowledge in Photonics by means of basic experiments, demonstrations and lectures by leading researchers and teachers. Most of the needed resources to accomplish these activities are provided by the OSA, such as educational posters and a portable kit for demonstrating Optics to students. At this moment the USC-OSA Student Chapter is carrying out several activities, as educational journeys at the Santiago de Compostela University Hospital Complex (CHUS), where hospitalized children can approach to Optics through some simple experiments and games. A teaching program is also being organized in collaboration with Galician secondary schools in order to show students the importance and uses of Optics and Photonics and to arouse their interest in this field, as well as encouraging them to develop their scientific thinking. Another activity will take place in November during the Science Week, which includes a program of lectures targeted to undergraduate students and an exposition of several demonstrations

Nasal vs Oronasal CPAP for OSA Treatment: A Meta-Analysis.

Science.gov (United States)

Andrade, Rafaela G S; Viana, Fernanda M; Nascimento, Juliana A; Drager, Luciano F; Moffa, Adriano; Brunoni, André R; Genta, Pedro R; Lorenzi-Filho, Geraldo

2018-03-01

Nasal CPAP is the "gold standard" treatment for OSA. However, oronasal masks are frequently used in clinical practice. The aim of this study was to perform a meta-analysis of all randomized and nonrandomized trials that compared nasal vs oronasal masks on CPAP level, residual apnea-hypopnea index (AHI), and CPAP adherence to treat OSA. The Cochrane Central Register of Controlled Trials, Medline, and Web of Science were searched for relevant studies in any language with the following terms: "sleep apnea" and "CPAP" or "sleep apnea" and "oronasal mask" or "OSA" and "oronasal CPAP" or "oronasal mask" and "adherence." Studies on CPAP treatment for OSA were included, based on the following criteria: (1) original article; (2) randomized or nonrandomized trials; and (3) comparison between nasal and oronasal CPAP including pressure level, and/or residual AHI, and/or CPAP adherence. We identified five randomized and eight nonrandomized trials (4,563 patients) that reported CPAP level and/or residual AHI and/or CPAP adherence. Overall, the random-effects meta-analysis revealed that as compared with nasal, oronasal masks were associated with a significantly higher CPAP level (Hedges' g, -0.59; 95% CI, -0.82 to -0.37; P CPAP level, higher residual AHI, and poorer adherence than nasal masks. PROSPERO database; No.: CRD42017064584; URL: https://www.crd.york.ac.uk/prospero/. Copyright © 2017 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.

WBFSH aastakoosolek Varssavis. I-II osa / Raigo Kollom

Index Scriptorium Estoniae

Kollom, Raigo, 1936-

2013-01-01

Poolas 7.-9. oktoobrini Maailma Sporthobuste Kasvatajate Föderatsiooni peaassambleel toimunust ning loengutest ja aruteludest: Hobuste "genoomilisest aretusest", Jõudluskontrolli ja terviseandmete kasutamisest Rootsi aretuses, Hobuste lineaarse kirjeldamise meetodist, tõuraamatute tulevikust. Teises osas: Hobusekasvatuse seisust Poolas, Janow Podlaski hobusekasvatusest ja üldisest eluolust

Eastern Sources of Invitational Education.

Science.gov (United States)

Ryback, David

1993-01-01

Presents historical perspective suggesting that invitational theory shares many beliefs with ancient Eastern philosophies. Submits that teachers and other educators who embrace the invitational perspective may benefit from an understanding of Eastern principles. Briefly describes Buddhism, Confucianism, Taoism, Zen Buddhism, and their relevance to…

Increased MCP-1 gene expression in monocytes of severe OSA patients and under intermittent hypoxia.

Science.gov (United States)

Chuang, Li-Pang; Chen, Ning-Hung; Lin, Yuling; Ko, Wen-Shan; Pang, Jong-Hwei S

2016-03-01

Obstructive sleep apnea (OSA) is known to be a risk factor of coronary artery disease. Monocyte chemoattractant protein-1 (MCP-1), as a critical factor for monocyte infiltration, is known to play a role in the development of atherosclerosis. This study aimed to investigate the effect of intermittent hypoxia, the hallmark of OSA, on the MCP-1 expression of monocytes. Peripheral blood was sampled from 61 adults enrolled for suspected OSA. RNA was prepared from the isolated monocytes for the analysis of MCP-1. The effect of in vitro intermittent hypoxia on the regulation and function of MCP-1 was investigated on THP-1 monocytic cells and human monocytes. The mRNA and secreted protein levels were investigated by RT/real-time PCR and enzyme-linked immunosorbent assay, respectively. Monocytic MCP-1 gene expression was found to be increased significantly in severe OSA patients. In vitro intermittent hypoxia was demonstrated to increase the mRNA and protein expression levels of MCP-1 dose- and time-dependently in THP-1 monocytic cells. The MCP-1 mRNA expression in monocytes isolated from OSA patient was induced to a much higher level compared to that from normal control. Pre-treatment with inhibitor for p42/44 MAPK or p38 MAPK suppressed the activation of MCP-1 expression by intermittent hypoxia. This is the first study to demonstrate the increase of MCP-1 gene expression in monocytes of severe OSA patients. In addition, monocytic MCP-1 gene expression can be induced under intermittent hypoxia.

Converting a manned LCU into an unmanned surface vehicle (USV): an open systems architecture (OSA) case study

OpenAIRE

Smith, Montrell F.

2014-01-01

Approved for public release; distribution is unlimited This thesis demonstrates the process by which the concepts of open systems architecture (OSA) might be applied within the context of an existing systems engineering methodology to result in a flexible system. This is accomplished by combining an existing systems engineering process model with OSA management and business principles to execute a successful asset-repurposing program. To demonstrate utility of this OSA approach to systems ...

Association of Type D personality to perceived side effects and adherence in CPAP-treated patients with OSAS.

Science.gov (United States)

Broström, Anders; Strömberg, Anna; Mårtensson, Jan; Ulander, Martin; Harder, Lena; Svanborg, Eva

2007-12-01

Continuous positive airway pressure (CPAP) is the treatment of choice for obstructive sleep apnoea syndrome (OSAS), but side effects are common and long-term adherence low. The Type D (distressed) personality is defined as a combination of negative affectivity and social inhibition. The association of Type D personality with adherence has not been studied in CPAP-treated patients with OSAS. This study aimed to describe the prevalence of Type D personality in OSAS patients with CPAP treatment longer than 6 months and the association with self-reported side effects and adherence. A cross-sectional descriptive design was used. A total of 247 OSAS patients with a mean use of CPAP treatment for 55 months (6-182 months) were included. Data collection was achieved by two questionnaires; the Type D scale 14 (DS14) (Type D personality), SECI (side effects of CPAP), as well as from medical records (clinical variables and objective adherence to CPAP treatment). Type D personality occurred in 30% of the patients with OSAS and significantly (P < 0.05-0.001) increased the perceived frequency and severity of a broad range of side effects. The objective adherence was significantly lower (P < 0.001) for OSAS patients with Type D compared to OSAS patients without Type D, both with regard to a mean use of 4 h per night and 85% of the self-rated sleep time per night. The additional effect of a Type D personality on perceived side effects and adherence to CPAP treatment found in this study could be used by healthcare personnel when evaluating patients waiting for treatment.

OSAS Surgery and Postoperative Discomfort: Phase I Surgery versus Phase II Surgery

Directory of Open Access Journals (Sweden)

Giulio Gasparini

2015-01-01

Full Text Available Introduction. This study aims to investigate the reasons that discourage the patients affected by OSAS to undergo orthognathic surgery and compares the postoperative discomfort of phase I (soft tissue surgery and phase II (orthognathic surgery procedures for treatment of OSAS. Material and Methods. A pool of 46 patients affected by OSAS was divided into two groups: “surgery patients” who accepted surgical treatments of their condition and “no surgery patients” who refused surgical procedures. The “surgery patients” group was further subdivided into two arms: patients who accepted phase I procedures (IP and those who accepted phase II (IIP. To better understand the motivations behind the refusal of II phase procedures, we asked the patients belonging to both the IP group and “no surgery” group to indicate the main reason that influenced their decision to avoid II phase procedures. We also monitored and compared five parameters of postoperative discomfort: pain, painkiller assumption, length of hospitalization, foreign body sensation, and diet assumption following IP and IIP procedures. Results. The main reason to avoid IIP procedures was the concern of a more severe postoperative discomfort. Comparison of the postoperative discomfort following IP versus IIP procedures showed that the former scored worse in 4 out of 5 parameters analyzed. Conclusion. IIP procedures produce less postoperative discomfort. IIP procedures, namely, orthognathic surgery, should be the first choice intervention in patients affected by OSAS and dentoskeletal malformation.

Invited and contributed papers presented by the theory group at the joint Varenna-Lausanne international workshop 'theory of fusion plasmas'

International Nuclear Information System (INIS)

1996-09-01

In this report eight invited and contributed papers of the theory group are included which were presented at joint Varenna-Lausanne international workshop on 'theory of fusion plasmas'. (author) figs., tabs., refs

Examining uptake of online education on obstructive sleep apnoea in general practitioners: a randomised trial.

Science.gov (United States)

Paul, Christine; Rose, Shiho; Hensley, Michael; Pretto, Jeffrey; Hardy, Margaret; Henskens, Frans; Clinton-McHarg, Tara; Carey, Mariko

2016-07-19

Obstructive sleep apnoea (OSA) affects up to 28 % of the adult population in Western countries. The detection and management of OSA by general practitioners (GPs) can be poor. The study aimed to examine what influence enhanced invitations had on uptake of on-line learning modules for OSA by GPs, and whether recent referrals of patients to sleep specialists influenced uptake. Practicing GPs in regional Australia were identified and randomised to receive either an enhanced or standard invitation letter to a new on-line education module for OSA. The enhanced letter included indication that the module was eligible for professional accreditation and described the prevalence and burden of sleep disorders. Some included extra emphasis if the GP had recently referred a patient for diagnostic investigation of OSA. Two reminder letters were sent. Of 796 eligible GPs who received the letters, sixteen (2 %) accessed the website and four completed the modules over the four-month study period. GPs who received an enhanced invitation letter were not significantly more likely to access the website compared to GPs who received the standard invitation letter. Recent referral of a patient for diagnostic investigation was also not a significant factor in influencing use of the module. GP interest in on-line education about OSA appears low, and emphasis of relevant recent past patient(s) and the opportunity for professional education points was not successful in increasing engagement. There is a need to identify effective approaches to improving the detection and management of OSA in general practice.

Determinação de resíduos de organoclorados em águas fluviais do município de Viçosa - MG Determination of organochlorinated present in river from the region of Viçosa, MG

Directory of Open Access Journals (Sweden)

Cíntia Maria Chagas

1999-07-01

Full Text Available In this work the contamination, by organochlorinated, of a drinking water source located in the region of Viçosa, MG, was evaluated. The identification and quantification of the analytes was carried out using a gas-chromatograph equipped with an electron capture detector after liquid-liquid extraction and concentration. Four insecticides, Aldrin, Epoxy heptachloride, Endrin and op'- DDT were detected in concentrations that are higher than the safety limits established in the Brazilian legislation.

Teadusseltside osa rahvuskultuuris ja Õpetatud Eesti Selts / Tiit Rosenberg

Index Scriptorium Estoniae

Rosenberg, Tiit, 1946-

2005-01-01

Seltsid said alguse 17. sajandil ja levisid Baltimaadesse 19. sajandiks. Ettekanne Eesti Teaduste Akadeemiaga assotsieerunud teadusseltside ühiskonverentsil (21.05.2003. a.) "Teadusseltside osa Eesti rahvusliku identiteedi kujunemisel ja säilimisel"

Influencing factors on CPAP adherence and anatomic characteristics of upper airway in OSA subjects.

Science.gov (United States)

Park, Pona; Kim, Jinil; Song, Yoon Jae; Lim, Jae Hyun; Cho, Sung Woo; Won, Tae-Bin; Han, Doo Hee; Kim, Dong-Young; Rhee, Chae Seo; Kim, Hyun Jik

2017-12-01

Although continuous positive airway pressure (CPAP) is the most effective treatment modality, poor adherence still remains a problem for obstructive sleep apnea (OSA) treatment and there is little evidence regarding how this might be improved. This study aims to analyze the anatomic and clinical factors of OSA subjects who failed to comply with CPAP therapy.The medical records of 47 OSA subjects who received CPAP therapy as a first-line treatment modality were retrospectively reviewed. The medical records were reviewed for demographic and polysomnographic data and anatomic findings of the nasal cavity and oropharynx.24 patients who adhered to CPAP therapy and 23 patients who were nonadherent were enrolled in the study. There were no statistically significant differences in sleep parameters between CPAP-adherent patients and CPAP nonadherent subjects. Mean body mass index of CPAP nonadherent group was significantly higher than CPAP adherent group. Higher grades of septal deviation and hypertrophic change of the inferior turbinate were observed more in the CPAP nonadherent group. In addition, CPAP nonadherent subjects showed considerably bigger tonsils and higher grade palatal position comparing with the CPAP adherent subjects. Subjective discomfort including inconvenience, mouth dryness, and chest discomfort were the main problems for OSA subjects who did not comply with CPAP therapy.Excessive upper airway blockage in the nasal cavity and oropharynx was predominant in CPAP nonadherent subjects, which might cause the reported subjective discomfort that reduces CPAP compliance. Therefore, resolution of these issues is needed to enhance CPAP compliance for control of OSA. Copyright © 2017 The Authors. Published by Wolters Kluwer Health, Inc. All rights reserved.

Piperaceae C. Agardh da Estação Experimental Mata do Paraíso, Viçosa, MG Piperaceae C. Agardh from the Experimental Station of "Mata do Paraíso", Viçosa, MG

Directory of Open Access Journals (Sweden)

Rita Maria de Carvalho-Okano

1998-01-01

Full Text Available Este trabalho consistiu no levantamento dos representantes de Piperaceae na Estação Experimental Mata do Paraíso, no município de Viçosa, MG (20º42'S e 42º55'W, coberta por Floresta Estacionai Semidecidual Montana. No período de março/97 a junho/98 foram realizadas 30 visitas quinzenais à Estação para coleta de material botânico que se encontra depositado no herbário VIC da Universidade Federal de Viçosa. Foram reconhecidos 18 táxons distribuídos nos gêneros Piper L. com 14 espécies, Ottonia Spreng. com três e Pothomorphe Miq. com uma espécie. As espécies mais abundantes foram Piper caldense C.DC., Piper gaudichaudianum Kunth e Piper vicosanum Yunck. São apresentadas chaves para identificação dos gêneros e espécies, descrições, ilustrações e comentários.An inventory of the Piperaceae species was made at the Experimental Station of "Mata do Paraíso" in Viçosa, Minas Gerais State (20º42'S and 42º55'W, an area covered by the Semideciduous Mesophytic Montana Forest. Thirty visits were made fortnightly to the station, from March/1997 to June/1998, in order to collect botanical material which was deposited in the VIC herbarium (Universidade Federal de Viçosa. Eighteen taxa, represented by the genera Piper L. (14 species, Ottonia Spreng (3 species, and Potliotnorplie Miq. (1 species were recognized. The most abundant species were Piper caldense CDC, Piper gaudichaudianum Kunth and Piper vicosanum Yunck. Identification keys for the genera and species as well as species descriptions, illustrations and comments are presented.

Assessment of the Depression, Anxiety, and Stress Scale (DASS-21) in untreated obstructive sleep apnea (OSA)

DEFF Research Database (Denmark)

Nanthakumar, Shenooka; Bucks, Romola S.; Skinner, Timothy C.

2017-01-01

compared the fit of Lovibond and Lovibond's (1995) correlated 3-factor structure of the DASS-21 and measurement invariance between a non-OSA and an OSA sample using confirmatory factor analysis. As measurement invariance was not found, to determine the source of non-invariance differential item functioning...... (DIF) was examined using dMACS. The correlated 3-factor structure (with correlated errors) of the DASS-21 was a better fit in the non-OSA sample. dMACS indicated that there was a degree of DIF for each of the subscales, especially for the Anxiety subscale, in which 2 symptoms (that are also...

Does CPAP treatment lead to gastroesophageal reflux in patients with moderate and severe OSA?

Science.gov (United States)

Ozcelik, Hatice; Kayar, Yusuf; Danalioglu, Ahmet; Arabaci, Elif; Uysal, Omer; Yakar, Fatih; Kart, Levent

2017-03-01

Obstructive sleep apnea (OSA) leads to upper respiratory tract obstruction, causing increased abdominal-gastric pressure and decreased lower esophageal sphincter (LES) pressure and thus gastroesophageal reflux (GER). Continuous positive airway pressure (CPAP) is known to be an effective method for OSA treatment, but its effect on GER is still controversial. There are a very few studies investigating CPAP and GER relationship and performed based on pre- and post-treatment objective parameters of GER in patients with OSA. The study investigated the effect of CPAP treatment in patients with moderate and severe OSA without GER complaints on pre- and post-treatment objective GER parameters. The study included 25 patients with respiratory disturbance indices >15 without reflux symptoms who had undergone polysomnography at sleep laboratory. Age, sex, body mass index (BMI), waist, and neck circumference of the patients were documented. DeMeester score, LES pressure, and polysomnography parameters were evaluated pre- and post-CPAP. The results were statistically evaluated, and p value CPAP phase, mean sphincter pressure was 22.2 ± 1.2 (range 8-73), and mean DeMeester score was 18 ± 15.5 (range 0.2-57). At the post-CPAP, mean sphincter pressure was 22.9 ± 1.6 (range 9-95), and mean DeMeester score was 16.3 ± 14.8 (range 0.2-55). No significant difference (p > 0.05) was found comparing pre-CPAP and post-CPAP measurements. Objective criteria show that CPAP treatment does not cause reflux in patients with OSA. Unlike studies reported in the literature, this conclusion has been reached by pre- and post-CPAP assessments.

Particle size and cholesterol content of a mayonnaise formulated by OSA-modified potato starch

Directory of Open Access Journals (Sweden)

Shiva Ghazaei

2015-03-01

Full Text Available Egg yolk was partially replaced (0, 25, 50, 75, and 100% with octenyl succinic anhydride (OSA-modified potato starch in a reduced-fat mayonnaise formulation to curtail the problems associated with high cholesterol and induced allergic reactions. The physicochemical properties included parameters such as: pH, fat content, and emulsion stability of the formulations analyzed. The samples with 75% and 100% egg yolk substitute showed the maximum emulsion stability (>95% after two of months storage, and they were selected according to cholesterol content, particle size distributions, dynamic rheological properties, microstructure, and sensory characteristic. A significant reduction (84-97% in the cholesterol content was observed in the selected samples. Particle size analysis showed that by increasing the amount of OSA starch, the oil droplets with the peak size of 70 µm engulfed by this compound became larger. The rheological tests elucidated that in the absence of egg yolk, OSA starch may not result in a final product with consistent texture and that the best ratio of the two emulsifiers (OSA starch/egg yolk to produce stable reduced-fat, low cholesterol mayonnaise is 75/25. The microscopic images confirmed the formation of a stable cohesive layer of starch surrounding the oil droplets emulsified in the samples selected.

A Formal Security Analysis of an OSA/Parlay Authentication Interface

NARCIS (Netherlands)

Corin, R.J.; Di Caprio, G.; Etalle, Sandro; Gnesi, S.; Lenzini, Gabriele; Moiso, C.

2005-01-01

We report on an experience in analyzing the security of the Trust and Security Management (TSM) protocol, an authentication procedure within the OSA/Parlay Application Program Interfaces (APIs) of the Open Service Access and Parlay Group. The experience has been conducted jointly by research

Osa Pärnu poliitikuid saab ärimeestelt igakuist tasu / Teet Roosaar

Index Scriptorium Estoniae

Roosaar, Teet, 1963-

2005-01-01

Kuigi Pärnu uus linnavalitsus kärpis volikogu liikmete äriühingute nõukogudest makstavat tasu poole väiksemaks, saab osa poliitikuid endiselt lisasissetulekut, teiste seas linnakassast doteeritavalt Pärnu ATP-lt

Migrantide raha hoiab vee peal suurt osa endisest NL-ist / Ahto Lobjakas

Index Scriptorium Estoniae

Lobjakas, Ahto, 1970-

2007-01-01

Brüsselis tutvustatud Maailmapanga uuringust, mille kohaselt on suure osa endise NSVL-i vabariikide jaoks arvestatav sissetulekuallikas migrantide kojusaadetud raha. Lisa: Lääne-Euroopasse ja Venemaale

Recognition of upper airway and surrounding structures at MRI in pediatric PCOS and OSAS

Science.gov (United States)

Tong, Yubing; Udupa, J. K.; Odhner, D.; Sin, Sanghun; Arens, Raanan

2013-03-01

Obstructive Sleep Apnea Syndrome (OSAS) is common in obese children with risk being 4.5 fold compared to normal control subjects. Polycystic Ovary Syndrome (PCOS) has recently been shown to be associated with OSAS that may further lead to significant cardiovascular and neuro-cognitive deficits. We are investigating image-based biomarkers to understand the architectural and dynamic changes in the upper airway and the surrounding hard and soft tissue structures via MRI in obese teenage children to study OSAS. At the previous SPIE conferences, we presented methods underlying Fuzzy Object Models (FOMs) for Automatic Anatomy Recognition (AAR) based on CT images of the thorax and the abdomen. The purpose of this paper is to demonstrate that the AAR approach is applicable to a different body region and image modality combination, namely in the study of upper airway structures via MRI. FOMs were built hierarchically, the smaller sub-objects forming the offspring of larger parent objects. FOMs encode the uncertainty and variability present in the form and relationships among the objects over a study population. Totally 11 basic objects (17 including composite) were modeled. Automatic recognition for the best pose of FOMs in a given image was implemented by using four methods - a one-shot method that does not require search, another three searching methods that include Fisher Linear Discriminate (FLD), a b-scale energy optimization strategy, and optimum threshold recognition method. In all, 30 multi-fold cross validation experiments based on 15 patient MRI data sets were carried out to assess the accuracy of recognition. The results indicate that the objects can be recognized with an average location error of less than 5 mm or 2-3 voxels. Then the iterative relative fuzzy connectedness (IRFC) algorithm was adopted for delineation of the target organs based on the recognized results. The delineation results showed an overall FP and TP volume fraction of 0.02 and 0.93.

Frequency of obstructive sleep apnea (OSA in patients with gastroesophageal reflux disease (GERD and the effect of nasal continuous positive airway pressure

Directory of Open Access Journals (Sweden)

Amany Shaker

2016-10-01

Conclusion: (1 A high risk for OSA development is more frequent in GERD patients especially NERD ones and who experience nighttime symptoms, (2 there is a mutual relationship between OSA and GERD reinforcing each other, and (3 CPAP therapy has a good role in the treatment of both OSA and GERD symptoms.

The utility of the elbow sign in the diagnosis of OSA

Directory of Open Access Journals (Sweden)

Haytham Samy Diab

2015-04-01

Conclusion: The elbow sign questionnaire is a simple and quick screening tool for OSA with good sensitivity and specificity in comparison to other questionnaires, further studies are needed in other populations to determine its reliability and predictive utility.

Treatment of OSA with CPAP Is Associated with Improvement in PTSD Symptoms among Veterans

Science.gov (United States)

Orr, Jeremy E.; Smales, Carolina; Alexander, Thomas H.; Stepnowsky, Carl; Pillar, Giora; Malhotra, Atul; Sarmiento, Kathleen F.

2017-01-01

Study Objectives: Posttraumatic stress disorder (PTSD) is common among veterans of the military, with sleep disturbance as a hallmark manifestation. A growing body of research has suggested a link between obstructive sleep apnea and PTSD, potentially due to obstructive sleep apnea (OSA) related sleep disruption, or via other mechanisms. We examined the hypothesis that treatment of OSA with positive airway pressure would reduce PTSD symptoms over 6 months. Methods: A prospective study of Veterans with confirmed PTSD and new diagnosis of OSA not yet using PAP therapy were recruited from a Veteran's Affairs sleep medicine clinic. All subjects were instructed to use PAP each night. Assessments were performed at 3 and 6 months. The primary outcome was a reduction in PTSD symptoms at 6 months. Results: Fifty-nine subjects were enrolled; 32 remained in the study at 6 months. A significant reduction in PTSD symptoms, measured by PCL-S score was observed over the course of the study (60.6 ± 2.7 versus 52.3 ± 3.2 points; p J Clin Sleep Med. 2017;13(1):57–63. PMID:27707436

High Adherence to CPAP Treatment Does Not Prevent the Continuation of Weight Gain among Severely Obese OSAS Patients

Science.gov (United States)

Myllylä, Minna; Kurki, Samu; Anttalainen, Ulla; Saaresranta, Tarja; Laitinen, Tarja

2016-01-01

Study Objectives: Obstructive sleep apnea syndrome (OSAS) patients benefit from continuous positive airway pressure (CPAP) treatment in a dose-response manner. We determined adherence and weight control, as well as their predictors, among long-term CPAP users. Methods: Cohort of 1,023 OSAS patients had used CPAP on average of 6.6 ± 1.2 years. BMI was determined at baseline and at follow-up visits. There were 7.4 ± 1.7 BMI and 6.5 ± 1.8 CPAP usage measurements per patient on average. Using the Bayesian hierarchical model, we determined the patients' individual trends of BMI and adherence development. Patients with significantly increasing or decreasing trends were identified at the posterior probability level of > 90%. Results: The mean age in the cohort was 55.6 ± 9.8 years, BMI 33.5 ± 6.4 kg/m2, apnea-hypopnea index 33.7 ± 23.1, and CPAP usage 6.0 ± 1.8 h/day. The majority of patients had no significant change in BMI (mean annual weight gain 0.04 ± 0.29 kg/m2) or CPAP adherence (mean annual increase 11.4 ± 7.0 min/day). However, at the individual level, 10% of the patients showed significant annual weight gain (0.63 ± 0.35 kg/m2) during the 5-year follow-up period. At baseline these patients were already more severely obese (mean BMI 40.0 ± 5.9 kg/m2) despite being younger (mean 50.9 ± 9.5 years) than the rest of the cohort. Conclusions: In the majority of CPAP-treated OSAS patients, weight did not significantly change but gained slightly slower than in age-matched population in general. However, in 10% of patients, high adherence to CPAP treatment did not prevent the continuation of weight gain. These patients present a high-risk group for OSAS-related multimorbidity later in life. Citation: Myllylä M, Kurki S, Anttalainen U, Saaresranta T, Laitinen T. High adherence to CPAP treatment does not prevent the continuation of weight gain among severely obese OSAS patients. J Clin Sleep Med 2016;12(4):519–528. PMID:26888588

Perfil cualitativo de metabolitos secundarios en la fracción comestible de especies leñosas seleccionadas por vacunos en un bosque semicaducifolio

Directory of Open Access Journals (Sweden)

Á Ojeda

Full Text Available Con el fin de caracterizar cualitativamente el perfil de metabolitos secundarios de la fracción comestible de plantas leñosas seleccionadas por vacunos en silvopastoreo, las cuales se encuentran en un bosque tropófilo semicaducifolio de Venezuela, se utilizaron 14 vacunos machos Brahman x Holstein de 390,4 ± 18,0 kg de PV. Estos fueron manejados en pastoreo continuo en una superficie de 81 ha, de las cuales 50 ha correspondían a un bosque semicaducifolio y el resto, a vegetación herbácea natural (Cynodon nlemfuensis, Sporobolus indicus, Axonopus sp., Mimosa pudica e Hyptis suaveolens. La composición de la biomasa leñosa seleccionada por los animales se estudió mediante la evaluación de los fragmentos epidérmicos presentes en las heces colectadas por vía transrectal, cada 15 días. A partir de estos resultados, se tomaron muestras de cinco plantas por especie leñosa, en los periodos seco y lluvioso. Se determinaron 15 grupos de metabolitos: alcaloides, á-aminos, carbohidratos solubles, cardenólidos, cianógenos, esteroles, fenoles totales, flavonoides, lectinas, mucílagos, quinonas, saponinas, taninos extractables (totales y condensados y terpenoides. La mayoría de la biomasa correspondió a especies de la familia Fabaceae, las cuales presentaron todos los metabolitos evaluados. En ambos periodos se detectaron niveles de esteroles, terpenoides, fenoles totales y taninos extractables que variaron desde leves hasta cuantiosos. Con independencia del periodo, el 66,7 % de las especies presentó entre 10-11 metabolitos secundarios en su biomasa comestible. Se recomienda realizar estudios para la cuantificación de los metabolitos secundarios presentes en plantas leñosas de valor forrajero, para este sistema silvopastoril

Olulist pärimisseadusest. [1.-3. osa] / Albert Paltser

Index Scriptorium Estoniae

Paltser, Albert, 1931-2007

1998-01-01

Pärandamise ja pärimise liikidest, esimese, teise ja kolmanda järjekorra seadusjärgsetest pärijatest ning abikaasa õigusest eelosale. Testamendi liikidest (notariaalne testament, notari hoiule antud testament, kodune testament), pärija pärandi osa määramisest testamendis, annakust, ase- ja järelpärijast, testamendi tühistamisest ja abikaasade vastastikusest testamendist. Pärimislepingust ja pärandi sundosast

The comparison of nasal surgery and CPAP on daytime sleepiness in patients with OSAS.

Science.gov (United States)

Tagaya, M; Otake, H; Suzuki, K; Yasuma, F; Yamamoto, H; Noda, A; Nishimura, Y; Sone, M; Nakashima, T; Nakata, S

2017-09-01

Residual sleepiness after continuous positive airway pressure (CPAP) is a critical problem in some patients with obstructive sleep apnea syndrome (OSAS). However, nasal surgery is likely to reduce daytime sleepiness and feelings of unrefreshed sleep. The aim of this study is to clarify the effects of nasal surgery and CPAP on daytime sleepiness. This is a retrospective and matched-case control study. The participants were consecutive 40 patients with OSAS who underwent nasal surgery (Surgery group) and 40 matched patients who were treated with CPAP (CPAP group). In the Surgery group, although the nasal surgery did not decrease either apnea or hypopnea, it improved oxygenation, the quality of sleep. In the CPAP Group, the CPAP treatment reduced apnea and hypopnea, and improved oxygenation, quality of sleep. The degree of relief from daytime sleepiness was different between the two groups. The improvement of Epworth Sleepiness Scale was more significant in the Surgery Group than those in the CPAP Group (Surgery from 11.0 to 5.1, CPAP from 10.0 to 6.2). These findings suggest that the results of the nasal surgery is more satisfactory for some patients with OSAS than CPAP on daytime sleepiness.

Lizards and Amphisbaenians, municipality of Viçosa, state of Minas Gerais, southeastern Brazil

Directory of Open Access Journals (Sweden)

Rodrigues, A. C.

2009-01-01

Full Text Available We performed a survey of lizards and amphisbaenians from municipality of Viçosa, in Atlantic Forest from state ofMinas Gerais, southeastern Brazil, based on data of the herpetological collections of Museu de Zoologia João Moojen,Universidade Federal de Viçosa, and Museu de Zoologia, Universidade de São Paulo. One hundred and forty sixspecimens of 14 species were analyzed, belonging to the following families: Amphisbaenidae, Anguidae, Gekkonidae,Gymnophthalmidae, Leiosauridae, Polychrotidae, Scincidae, Teiidae and Tropiduridae. We hope to supply basicinformation that helps to understand species distribution of this group in the Atlantic Forest of Minas Gerais andsoutheastern Brazil.

Effect of CPAP Withdrawal on BP in OSA: Data from Three Randomized Controlled Trials.

Science.gov (United States)

Schwarz, Esther I; Schlatzer, Christian; Rossi, Valentina A; Stradling, John R; Kohler, Malcolm

2016-12-01

Based on meta-analyses, the BP-lowering effect of CPAP therapy in patients with OSA is reported to be approximately 2 to 3 mm Hg. This figure is derived from heterogeneous trials, which are often limited by poor CPAP adherence, and thus the treatment effect may possibly be underestimated. We analyzed morning BP data from three randomized controlled CPAP withdrawal trials, which included only patients with optimal CPAP compliance. Within the three trials, 149 patients with OSA who were receiving CPAP were randomized to continue therapeutic CPAP (n = 65) or to withdraw CPAP (n = 84) for 2 weeks. Morning BP was measured at home before and after sleep studies in the hospital. CPAP withdrawal was associated with a return of OSA (apnea-hypopnea index [AHI] at a baseline of 2.8/h and at follow-up of 33.2/h). Office systolic BP (SBP) increased in the CPAP withdrawal group compared with the CPAP continuation group by +5.4 mm Hg (95% CI, 1.8-8.9 mm Hg; P = .003) and in the home SBP group by +9.0 mm Hg (95% CI, 5.7-12.3 mm Hg; P CPAP withdrawal results in a clinically relevant increase in BP, which is considerably higher than in conventional CPAP trials; it is also underestimated when office BP is used. Greater OSA severity is associated with a higher BP rise in response to CPAP withdrawal. ClinicalTrials.gov; No.: NCT01332175 and NCT01797653) URL: www.clinicaltrials.gov and ISRCTN registry (ISRCTN 93153804) URL: http://www.isrctn.com/. Copyright © 2016 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.

Lack of effect of sleep apnea on oxidative stress in obstructive sleep apnea syndrome (OSAS patients.

Directory of Open Access Journals (Sweden)

M Simiakakis

Full Text Available PURPOSE: The aim of this study was to evaluate markers of systemic oxidative stress and antioxidant capacity in subjects with and without OSAS in order to investigate the most important factors that determine the oxidant-antioxidant status. METHODS: A total of 66 subjects referred to our Sleep laboratory were examined by full polysomnography. Oxidative stress and antioxidant activity were assessed by measurement of the derivatives of reactive oxygen metabolites (d-ROMs and the biological antioxidant capacity (BAP in blood samples taken in the morning after the sleep study. Known risk factors for oxidative stress, such as age, sex, obesity, smoking, hypelipidemia, and hypertension, were investigated as possible confounding factors. RESULTS: 42 patients with OSAS (Apnea-Hypopnea index >15 events/hour were compared with 24 controls (AHI<5. The levels of d-ROMS were significantly higher (p = 0.005 in the control group but the levels of antioxidant capacity were significantly lower (p = 0.004 in OSAS patients. The most important factors predicting the variance of oxidative stress were obesity, smoking habit, and sex. Parameters of sleep apnea severity were not associated with oxidative stress. Minimal oxygen desaturation and smoking habit were the most important predicting factors of BAP levels. CONCLUSION: Obesity, smoking, and sex are the most important determinants of oxidative stress in OSAS subjects. Sleep apnea might enhance oxidative stress by the reduction of antioxidant capacity of blood due to nocturnal hypoxia.

Obstructive Sleep Apnea

Medline Plus

Full Text Available ... can also invite bacteria that lead to gum disease. Click here to find out more. Obstructive Sleep Apnea (OSA) Download Download the ebook for further information Obstructive sleep ... high blood pressure, heart disease and decreased libido. In addition, OSA causes daytime ...

The rheological properties of blood and the risk of cardiovascular disease in patients with obstructive sleep apnea syndrome (OSAS

Directory of Open Access Journals (Sweden)

Władysław Pierzchała

2011-07-01

Full Text Available Obstructive sleep apnea (OSA is an important public health concern, which affects around 2–4% of the population. Left untreated, it causes a decrease not only in quality of life, but also of life expectancy. Despite the fact that knowledge about the mechanisms of development of cardiovascular disease in patients with OSA is still incomplete, observations confirm a relationship between sleep disordered breathing and the rheological properties of blood. One possible consequence of an increased incidence of cardiovascular disease may be a rise in mortality in OSA patients. Continuously improved research methods are allowing for an increasingly more accurate understanding of the significance of observed changes. (Folia Histochemica et Cytobiologica 2011, Vol. 49, No. 2, 206–210

Comparability of pulse oximeters used in sleep medicine for the screening of OSA

International Nuclear Information System (INIS)

Böhning, N; Schultheiß, B; Eilers, S; Schmittendorf, E; Penzel, T; Böhning, W

2010-01-01

Obstructive sleep apnea syndrome (OSA) is a frequent clinical picture. It is characterized by repetitive respiratory arrest with a consecutive decrease in arterial oxygen saturation (SaO 2 ). In clinical practice, the number of desaturations per hour, oxygen desaturation index (ODI), is used as an important diagnostic criterion. Medical literature, however, mentions different threshold values that are defined as pathological. By means of systematic comparative measurements, the study presented here will examine to what extent the diagnosis and the quantification of OSA severity are affected by the device-specific measurement technique, thus impacting the predictive value of nighttime pulse oximetry in outpatient OSA screening. Different pulse oximeters commonly used in clinical practice were analyzed comparatively regarding technical parameters, temporal dynamics and the reproducibility of measuring results. The measurements were executed simultaneously and time synchronized in a reference group of five test subjects (four males, one female, average age 33.0 ± 9.4 years), in a group of five patients (all males, average age 51.8 ± 18.4 years) and using a simulator (pulse oximeter simulator index 2). All devices underestimate the simulator's predetermined oxygen desaturation of 10%. The dispersion of values is high. The device-specific characteristics have a significant influence on the collected data. The fundamental weakness of the systems lies in the reproducibility of measuring results (this only seems adequate at a signal resolution in steps of 0.1%) as well as the differing temporal dynamics. In the synchronous use of different systems on patients for the purpose of a direct comparison of devices, the dispersion of values is serious, reaching a fluctuation range of up to factor 1.42. In measuring dynamic events (apneas), different pulse oximeters do not record identical values. This is due to the different internal signal processing of the devices

Invited and contributed papers presented at the 22. EPS conference on controlled fusion and plasma physics

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-08-01

In this report one invited and fifteen contributed papers by researchers of the `Centre de Recherche en Physique des Plasmas`, Lausanne, to the 22. EPS Conference on Controlled Fusion and Plasma Physics are assembled. figs., tabs., refs.

Cognition and nocturnal disturbance in OSA: the importance of accounting for age and premorbid intelligence

DEFF Research Database (Denmark)

Olaithe, Michelle; Skinner, Timothy C.; Hillman, David

2015-01-01

and a tertiary hospital sleep clinic. All underwent comprehensive, laboratory-based polysomnography (PSG) and completed assessments of cognition including attention, short- and long-term memory and executive function. Structural equation modelling (SEM) was used to construct a theoretically-driven model......© 2014, Springer-Verlag Berlin Heidelberg. Introduction: Obstructive sleep apnea (OSA) is a common disorder that is associated with impaired attention, memory and executive function. However, the mechanisms underlying such dysfunction are unclear. To determine the influence of sleep fragmentation...... these significant relationships. No significant predictors of memory function were found. Conclusions: The mechanisms underlying the effects of OSA on cognition remain to be defined. Implications are discussed in light of these findings....

Changes of plasma IL-6 and TNF-α levels after CPAP treatment in patients with obstructive sleep apnea syndrome (OSAS)

International Nuclear Information System (INIS)

Cao Zhuo; Wang Liangxing

2009-01-01

Objective: To investigate the changes of plasma IL-6 and TNF-α levels after continuous positive airway pressure (CPAP) therapy in patients with obstructive sleep apnea syndrome (OSAS). Methods: Plasma IL-6 and TNF-α levels were measured with RIA in 60 patients with OSAS both before and after CPAS therapy as well as in 30 controls. Results: Before CPAP therapy, the plasma IL-6 and TNF-α levels in patients with OSAS were significantly higher than those in controls (25.92 ± 4.48pg/ ml and 11.27 ± 2.60pg/ml vs 13.21 ± 1.97pg/ml and 5.83±0.99pg/mi, P 2 level (r=-0.495, 0.483, P<0.05). After treatment with CPAP for three months, the plasma IL-6 and TNF-α levels were significantly decreased (15.37±1.78pg/ml and 6.79±0.87pg/ml, vs pre-treatment levels, P<0.05, P<0.01). Conclusion: CPAP therapy could effectively decrease the plasma IL-6 and TNF-α levels in patients with OSAS. (authors)

Bid invitations for nuclear power stations

International Nuclear Information System (INIS)

Zijl, N.A. van.

1975-01-01

Types of bid invitations, basic requirements on bid invitation documents, basic content of a turnkey bid invitation (bid invitation letter, instructions to the bidders, terms and conditions of the draft contract, technical specifications, site data and information), nuclear fuel procurement, differences turnkey - non-turnkey, legal, commerical, and technical matters concerning the contract document. (HP) [de

The efficacy of a brief motivational enhancement education program on CPAP adherence in OSA: a randomized controlled trial.

Science.gov (United States)

Lai, Agnes Y K; Fong, Daniel Y T; Lam, Jamie C M; Weaver, Terri E; Ip, Mary S M

2014-09-01

Poor adherence to CPAP treatment in OSA adversely affects the effectiveness of this therapy. This randomized controlled trial (RCT) examined the efficacy of a brief motivational enhancement education program in improving adherence to CPAP treatment in subjects with OSA. Subjects with newly diagnosed OSA were recruited into this RCT. The control group received usual advice on the importance of CPAP therapy and its care. The intervention group received usual care plus a brief motivational enhancement education program directed at enhancing the subjects' knowledge, motivation, and self-efficacy to use CPAP through the use of a 25-min video, a 20-min patient-centered interview, and a 10-min telephone follow-up. Self-reported daytime sleepiness adherence-related cognitions and quality of life were assessed at 1 month and 3 months. CPAP usage data were downloaded at the completion of this 3-month study. One hundred subjects with OSA (mean ± SD, age 52 ± 10 years; Epworth Sleepiness Scales [ESS], 9 ± 5; median [interquartile range] apnea-hypopnea index, 29 [20, 53] events/h) prescribed CPAP treatment were recruited. The intervention group had better CPAP use (higher daily CPAP usage by 2 h/d [Cohen d = 1.33, P motivational enhancement education in addition to usual care were more likely to show better adherence to CPAP treatment, with greater improvements in treatment self-efficacy and daytime sleepiness. ClinicalTrials.gov; No.: NCT01173406; URL: www.clinicaltrials.gov.

Assessment and characterization of joineries in the city of Viçosa, MG/ Diagnóstico e caracterização das marcenarias na cidade de Viçosa, MG

Directory of Open Access Journals (Sweden)

José de Castro Silva

2008-07-01

Full Text Available The forestry sector is not only formed by large companies, such as pulp and paper or reconstituted panels, but also by small businesses, and often strictly family businesses, as joineries. This study aimed to identify, assess and characterize joineries in Viçosa, Minas Gerais. The object of study was limited to the city’s joinery businesses, mainly the ones belonging to the former Joiner’s Association. A questionnaire was drawn up to obtain information on the used wood, internal management and employee training, machinery, products, market, product advertising and prospects for the sector. It was found that both entrepreneurs and workers have low educational level and lack their own product design. They were producing only ordered products with intensive use of solid wood particularly from native forests. Products were heterogeneous, ranging from furniture to farm utilities. Competition, mainly the informal, represented the biggest obstacle to sector development, as well as serialized products from other locations sold in shops at lower prices. It was concluded that the joinery sector in Viçosa needs greater skill levels, both technical and managerial, to improve the activity. Moreover, the sector needs better organization through associations and support of agencies such as local Sebrae, and wider product advertising targeting consumers in the region.O setor florestal não é constituído apenas por grandes empresas, como as de celulose e papel ou de painéis reconstituídos, mas também por pequenas empresas, muitas das vezes estritamente familiares, como as marcenarias. O presente trabalho teve por objetivo a identificação, diagnóstico e caracterização das marcenarias de Viçosa, Estado de Minas Gerais. Delimitaram-se, como objeto de estudo, as empresas de marcenaria da cidade, principalmente, pertencentes ao antigo Núcleo de Marceneiros. Elaborou-se um questionário para buscar informações sobre a madeira utilizada

Sleep fragmentation: comparison of two definitions of short arousals during sleep in OSAS patients.

Science.gov (United States)

Smurra, M V; Dury, M; Aubert, G; Rodenstein, D O; Liistro, G

2001-04-01

The measurement of arousals during sleep is useful to quantify sleep fragmentation. The criteria for electroencephalography (EEG) arousals defined by the American Sleep Disorders Association (ASDA) have recently been criticized because of lack of interobserver agreement. The authors have adopted a scoring method that associates the increase in chin electromyography (EMG) with the occurrence of an alpha-rhythm in all sleep stages (Université Catholique de Louvain (UCL) definition of arousals). The aim of the present study was to compare the two scoring definitions in terms of agreement and repeatability and the time taken for scoring in patients with obstructive sleep apnoea syndrome (OSAS) of varying severity. Two readers using both ASDA and UCL definitions scored twenty polysomnographies (PSGs) each on two occasions. The PSGs were chosen retrospectively to represent a wide range of arousal index (from 6-82) in OSAS patients. There was no difference in the arousal indices between readers and between scoring methods. The mean+/-SD difference between the two definitions (the bias) was 1.1+/-3.76 (95% confidence interval: -0.66-2.86). There was a strong linear relationship between the arousal index scored with the two definitions (r=0.981, pASDA definitions (18.5+/-5.4 versus 25.3+/-6.6 min, p<0.001). In conclusion, it has been found that in obstructive sleep apnoea syndrome patients, the American Sleep Disorders Association and Université Catholique de Louvain definitions were comparable in terms of agreement and repeatability.

Detection of Secondary Causes and Coexisting Diseases in Hypertensive Patients: OSA and PA Are the Common Causes Associated with Hypertension.

Science.gov (United States)

Wang, Lei; Li, Nanfang; Yao, Xiaoguang; Chang, Guijuan; Zhang, Delian; Heizhati, Mulalibieke; Wang, Menghui; Luo, Qin; Kong, Jianqiong

2017-01-01

Since the control rate of blood pressure is lower in mainland China, the aim of this study is to investigate the proportion of secondary causes and coexisting diseases of hypertension in hypertensive patients. Data on consecutive patients with hypertension who visited the Hypertension Center. Diseases were detected using an established strict screening protocol. Detection rate of secondary causes and coexisting diseases of hypertension was 39.5% among 3003 hypertensive patients. Obstructive sleep apnea (OSA) was the most common, accounting for 24.7% of patients, followed by primary aldosteronism (PA) (5.8%) and PA + OSA (4.9%). Endocrine hypertension accounted for 12.1% of patients, including 10.7% of patients with PA, 1.1% with hypothyroidism, 0.1% with pheochromocytoma, 0.1% with Cushing's syndrome, and 0.1% with hyperthyroidism, respectively. Those who smoke, those who are obese, and those who have diabetes accounted for 31.3%, 27.5%, and 16.6% of total patients, respectively. There were overlapping conditions in secondary causes and coexisting diseases of hypertension. OSA was the most common in each age- and BMI-stratified group. Findings from the current study suggest an increasing frequency of secondary forms of hypertension, highlighting the burden of OSA and PA in hypertensive patients.

Detection of Secondary Causes and Coexisting Diseases in Hypertensive Patients: OSA and PA Are the Common Causes Associated with Hypertension

Directory of Open Access Journals (Sweden)

Lei Wang

2017-01-01

Full Text Available Background. Since the control rate of blood pressure is lower in mainland China, the aim of this study is to investigate the proportion of secondary causes and coexisting diseases of hypertension in hypertensive patients. Methods. Data on consecutive patients with hypertension who visited the Hypertension Center. Diseases were detected using an established strict screening protocol. Results. Detection rate of secondary causes and coexisting diseases of hypertension was 39.5% among 3003 hypertensive patients. Obstructive sleep apnea (OSA was the most common, accounting for 24.7% of patients, followed by primary aldosteronism (PA (5.8% and PA + OSA (4.9%. Endocrine hypertension accounted for 12.1% of patients, including 10.7% of patients with PA, 1.1% with hypothyroidism, 0.1% with pheochromocytoma, 0.1% with Cushing’s syndrome, and 0.1% with hyperthyroidism, respectively. Those who smoke, those who are obese, and those who have diabetes accounted for 31.3%, 27.5%, and 16.6% of total patients, respectively. There were overlapping conditions in secondary causes and coexisting diseases of hypertension. OSA was the most common in each age- and BMI-stratified group. Conclusion. Findings from the current study suggest an increasing frequency of secondary forms of hypertension, highlighting the burden of OSA and PA in hypertensive patients.

Topical nasal steroid treatment does not improve CPAP compliance in unselected patients with OSAS.

Science.gov (United States)

Strobel, Werner; Schlageter, Manuel; Andersson, Morgan; Miedinger, David; Chhajed, Prashant N; Tamm, Michael; Leuppi, Jörg D

2011-02-01

Continuous positive airways pressure (CPAP) for treatment of obstructive sleep apnea (OSA) can produce troublesome nasal symptoms (i.e. congestion, rhinorrhea) that may reduce the compliance of CPAP. Topical nasal steroids are often prescribed to reduce these side effects, although scientific data are scarce supporting any benefits of this treatment for CPAP-induced nasal side effects. To study whether a topical nasal steroid can reduce CPAP-induced nasal symptoms and improve CPAP adherence during the initial phase of OSA treatment. A randomized, double-blinded, placebo-controlled study with fluticasone propionate 100 μg/nasal cavity twice daily Treatment was started 10 days prior to and continued throughout the first 4 weeks of CPAP. 63 patients who were selected for CPAP treatment participated. Nasal symptoms were recorded, nasal patency was assessed and lung function was measured with a peak flow meter. The patients' adherence to CPAP was recorded by the CPAP device. Total nasal symptoms increased from baseline to 4 wks after CPAP use for both nasal treatments (p < 0.05). No differences in total nasal symptoms between treatments were seen (p = 1), and no differences in nasal peak flow values after treatment were seen (p = 0.11). Moreover, there were no differences in CPAP use between the treatments. Fluticasone propionate as a nasal topical steroid does not reduce CPAP-induced unwanted nasal side effects, and has no beneficial effect on CPAP compliance during the first four weeks of treatment in unselected patients with OSAS. Copyright © 2010 Elsevier Ltd. All rights reserved.

Invitational Education: Theory, Research and Practice

Science.gov (United States)

Haigh, Martin

2011-01-01

Invitational Theory argues that learning is enhanced when learners are positively encouraged or "invited" into the educational experience. Arising from perceptual and self-concept theory, Invitational Pedagogy is constructed on four principles: respect for people, trust, optimism and intentionality, and upon five pillars: people, places, policies,…

Oronasal mask may compromise the efficacy of continuous positive airway pressure on OSA treatment: is there evidence for avoiding the oronasal route?

Science.gov (United States)

Andrade, Rafaela Garcia Santos; Madeiro, Fernanda; Genta, Pedro Rodrigues; Lorenzi-Filho, Geraldo

2016-11-01

Continuous positive airway pressure (CPAP) delivered by nasal mask is the gold standard treatment for obstructive sleep apnea (OSA). However, oral and oronasal masks are also available. We considered experimental evidence and reviewed clinical trials that evaluated the impact of oral and oronasal mask on OSA treatment. One recent study in 18 OSA patients that slept with a customized oronasal mask with two sealed compartments showed that the change of CPAP flow from nasal to oronasal and oral caused upper airway obstruction because of posterior displacement of the tongue demonstrated by nasoendoscopy. Oral masks use a mouthpiece that may stabilize the jaw and the tongue and have shown to be effective. However, oral masks are not widely used in clinical practice. Four out of five observational studies and all five reviewed randomized studies showed a worse performance of oronasal when compared with nasal masks. Oronasal masks were associated with higher residual apnea-hypopnea index, lower adherence, more leaks, and less satisfaction than nasal mask in the majority of the studies. Nasal CPAP must be the first choice to treat OSA. Patients on oronasal mask should be carefully followed. VIDEO ABSTRACT.

11 CFR 100.137 - Invitations, food, and beverages.

Science.gov (United States)

2010-01-01

... 11 Federal Elections 1 2010-01-01 2010-01-01 false Invitations, food, and beverages. 100.137...) Exceptions to Expenditures § 100.137 Invitations, food, and beverages. The cost of invitations, food, and... invitations, food and beverages provided by the individual on behalf of the candidate does not exceed $1,000...

11 CFR 100.77 - Invitations, food, and beverages.

Science.gov (United States)

2010-01-01

... 11 Federal Elections 1 2010-01-01 2010-01-01 false Invitations, food, and beverages. 100.77...) Exceptions to Contributions § 100.77 Invitations, food, and beverages. The cost of invitations, food and... invitations, food and beverages provided by the individual on behalf of the candidate does not exceed $1,000...

SEA LEVEL RISE AND ITS POTENTIAL IMPACTS ON COASTAL URBAN AREA: A CASE OF ETI-OSA, NIGERIA

Directory of Open Access Journals (Sweden)

Ayodele Michael AGBOOLA

2016-10-01

Full Text Available This study examines the spatial extent of coastal urban development and its potential sensitivity to sea-level rise. The main aim of the study is to critically examine the extent of growth in Eti-Osa over time, and the potential impacts of sea leve rise. Landsat Enhanced Thematic Mapper Plus (ETM+ imageries of years 2000 and 2015 were used to evaluate the different land use type identified. Post-classification change detection method was used to evaluate the output of the maximum likelihood supervised classification analysis done. This was also used to estimate the changes induces through urban development on the environment which accounts for the biodiversity loss. ASTER GDEM 2 imagery of 2011 was used to generate the elevation data used for the inundation analysis. Thus, both Land use map of Eti-Osa in 2015 and the down scaled Sea-level rise scenarios (at 0.5 to 15 meters were used for the inundation mapping. Results obtained from this research affirms that indeed EtiOsa has been subjected to gross urban expansion giving room for diverse forms of environmental degradation among which are huge replacement of natural land cover with built-up, reclamation of wetlands and sand filling of water bodies. This basically illustrates growth but also the risk that accompanies the advent of excessive alteration of natural ecosystem as Sea-level rise projections imply in this research.

CPAP treatment supported by telemedicine does not improve blood pressure in high cardiovascular risk OSA patients: a randomized, controlled trial.

Science.gov (United States)

Mendelson, Monique; Vivodtzev, Isabelle; Tamisier, Renaud; Laplaud, David; Dias-Domingos, Sonia; Baguet, Jean-Philippe; Moreau, Laurent; Koltes, Christian; Chavez, Léonidas; De Lamberterie, Gilles; Herengt, Frédéric; Levy, Patrick; Flore, Patrice; Pépin, Jean-Louis

2014-11-01

Obstructive sleep apnea (OSA) has been associated with hypertension, which is one of the intermediary mechanisms leading to increased cardiovascular morbidity. This study aimed at evaluating the effects of a combination of continuous positive airway pressure (CPAP) and telemedicine support on blood pressure (BP) reduction in high cardiovascular risk OSA patients. A multi-center randomized controlled trial that compared standard CPAP care and CPAP care and a telemedicine intervention. Sleep clinics in France. 107 adult (18-65 years old) OSA patients (AHI > 15 events/h) with a high cardiovascular risk (cardiovascular SCORE > 5% or secondary prevention). Patients were randomized to either standard care CPAP (n = 53) or CPAP and telemedicine (n = 54). Patients assigned to telemedicine were equipped with a smartphone for uploading BP measurements, CPAP adherence, sleepiness, and quality of life data; in return, they received pictograms containing health-related messages. The main outcome was home self-measured BP and secondary outcomes were cardiovascular risk evolution, objective physical activity, CPAP adherence, sleepiness and quality of life. Self-measured BP did not improve in either group (telemedicine or standard care). Patients in primary prevention showed greater BP reduction with CPAP treatment than those in secondary prevention. CPAP treatment supported by telemedicine alone did not improve blood pressure and cardiovascular risk in high cardiovascular risk OSA patients. This study emphasizes the need for diet and physical activity training programs in addition to CPAP when aiming at decreasing cardiometabolic risk factors in these patients. ClinicalTrials.gov identifier: NCT01226641.

Perfil socioeconômico, nutricional e de antioxidantes de jovens fumantes, do município de Viçosa-MG

OpenAIRE

Batista, Ellencristina da Silva

2006-01-01

Com o objetivo de comparar o perfil socieconômico, nutricional e de antioxidantes de indivíduos jovens fumantes e não fumantes de Viçosa-MG, conduziu-se um estudo transversal controlado. Foram selecionados indivíduos fumantes e não fumantes de instituições de ensino da cidade de Viçosa-MG. Considerou-se como fumante o indivíduo que fumava pelo menos um cigarro diariamente, por pelo menos 30 dias antes do inicio do estudo, e não fumante o que nunca fumou e/ou não fumava esporadicamente. Os fum...

Rice microRNA osa-miR1848 targets the obtusifoliol 14α-demethylase gene OsCYP51G3 and mediates the biosynthesis of phytosterols and brassinosteroids during development and in response to stress.

Science.gov (United States)

Xia, Kuaifei; Ou, Xiaojing; Tang, Huadan; Wang, Ren; Wu, Ping; Jia, Yongxia; Wei, Xiaoyi; Xu, Xinlan; Kang, Seung-Hye; Kim, Seong-Ki; Zhang, Mingyong

2015-11-01

Phytosterols are membrane components or precursors for brassinosteroid (BR) biosynthesis. As they cannot be transported long distances, their homeostasis is tightly controlled through their biosynthesis and metabolism. However, it is unknown whether microRNAs are involved in their homeostatic regulation. Rice (Oryza sativa) plants transformed with microRNA osa-miR1848 and its target, the obtusifoliol 14α-demethylase gene, OsCYP51G3, were used to investigate the role of osa-miR1848 in the regulation of phytosterol biosynthesis. osa-miR1848 directs OsCYP51G3 mRNA cleavage to regulate phytosterol and BR biosynthesis in rice. The role of OsCYP51G3 as one of the osa-miR1848 targets is supported by the opposite expression patterns of osa-miR1848 and OsCYP51G3 in transgenic rice plants, and by the identification of OsCYP51G3 mRNA cleavage sites. Increased osa-miR1848 and decreased OsCYP51G3 expression reduced phytosterol and BR concentrations, and caused typical phenotypic changes related to phytosterol and BR deficiency, including dwarf plants, erect leaves, semi-sterile pollen grains, and shorter cells. Circadian expression of osa-miR1848 regulated the diurnal abundance of OsCYP51G3 transcript in developing organs, and the response of OsCYP51G3 to salt stress. We propose that osa-miR1848 regulates OsCYP51G3 expression posttranscriptionally, and mediates phytosterol and BR biosynthesis. osa-miR1848 and OsCYP51G3 might have potential applications in rice breeding to modulate leaf angle, and the size and quality of seeds. © 2015 The Authors. New Phytologist © 2015 New Phytologist Trust.

Control of OSA during automatic positive airway pressure titration in a clinical case series: predictors and accuracy of device download data.

Science.gov (United States)

Huang, Hsin-Chia Carol; Hillman, David R; McArdle, Nigel

2012-09-01

To investigate the factors associated with physiologic control of obstructive sleep apnea (OSA) during automatic positive airway pressure (APAP) titration in a clinical series. To also assess the usefulness of apnea-hypopnea index (AHI) data downloaded from the APAP device (Dev AHI). Retrospective review of a consecutive series of patients with OSA who underwent APAP titration (Autoset Spirit, ResMed, Bella Vista, New South Wales, Australia ) with simultaneous polysomnographic (PSG) monitoring in the sleep laboratory. Tertiary sleep clinic. There were 190 consecutive patients with OSA referred for APAP titration. There were 58% of patients who achieved optimal or good control of OSA (titration PSG AHI titration. The independent predictors of titration PSG AHI were a history of cardiac disease and elevated central apnea and arousal indices during the diagnostic study. Although the median and interquartile range (IQR) AHI from the device (7.0, 3.9-11.6 events/hr) was only slightly less than the PSG AHI (7.8, 3.9-14.4 events/hr, P = 0.04) during titration, case-by-case agreement between the two measures was poor (chi-square titration is often poor, and close clinical follow-up is particularly needed in patients with a history of cardiac disease or with high arousal or central apnea indices on the diagnostic study. Device AHI does not reliably assess control during APAP titration, and PSG assessment may be required if clinical response to treatment is poor. The findings relate to the ResMed AutoSet device and may not apply to other devices.

O tratamento dos doentes insanos de Vila Viçosa no hospital de Rilhafoles (segunda metade do século XIX

Directory of Open Access Journals (Sweden)

Lobo de Araújo, Maria Marta

2014-12-01

Full Text Available In this work we examined the procedural requirements related to the sending of insane patients of Vila Viçosa to the hospital of Rilhafoles, in the second half of the 19th century, and the relationships established with the hospital of this Alentejo town relating to the payment of treatment. Faced with a severe financial crisis, the hospital of Vila Viçosa systematically refused the responsibility to send the insane patients to the Rilhafoles hospital in an attempt to pass this burden on the administration of the county, being very reluctant to pay the bills that came to him from the hospital of São José. The conflict between the two institutions came to the monarch with no other alternative than the payment, the hospital of village of the Alentejo region proceeded to sending parcels of money, albeit way too late. For the realization of this work we use the books of the Misericórdia and the documents of the Civil Governor found of the city of Évora under the custody of the Distrital Archive of the same city. This documents results, basically, from the correspondence between the Misericórdia of Vila Viçosa, the council administrator and the civil governor of Évora.[pt] Neste trabalho analisamos os trâmites processuais respeitantes ao envio de doentes insanos de Vila Viçosa para o hospital de Rilhafoles, na segunda metade do século XIX, e as relações estabelecidas com o hospital desta vila alentejana relativamente ao pagamento do tratamento. A braços com uma grave crise financeira, o hospital de Vila Viçosa recusava sistematicamente a responsabilidade de enviar os alienados para Rilhafoles, numa tentativa de passar esse ónus para a administração do concelho, mostrando-se muito renitente no pagamento das faturas que lhe chegavam do hospital de São José. O conflito entre as duas instituições chegou ao monarca e sem outra alternativa que a do pagamento, o hospital da vila alentejana procedeu ao envio de parcelas de dinheiro

Student Theological Research as an Invitation

Directory of Open Access Journals (Sweden)

William Badke

2011-12-01

Full Text Available Seminary students, despite having graduated from bachelors programs, struggle to make sense of the goals, processes, skills, and resources of research as graduate students. Beyond brief introductions to research, a scattered number of seminaries have developed either a separate theological information literacy course or have taken a through-the-curriculum approach to enhancing the information abilities of students. The former, however, separates information literacy from the curriculum, while the latter is difficult to implement and maintain. Living in a world of information glut, seminary professors are finding that traditional information dissemination models of education are becoming less viable. What is more, such models tend to teach students about a discipline rather than inviting them into it. These problems present a unique opportunity to place the teaching of information literacy at the foundation of theological education. With such an approach, students may be invited into the disciplines of their professors and enabled to practice these disciplines, thus becoming equipped to turn knowledge into praxis.

Genetics of Euglossini bees (Hymenoptera in fragments of the Atlantic Forest in the region of Viçosa, MG

Directory of Open Access Journals (Sweden)

A. M. Waldschmidt

Full Text Available With uncontrolled deforestation, forest fragments remain, which in most cases are in different stages of regeneration and present isolated populations. In the present study we analyzed the genetic patterns of Eulaema nigrita populations in seven Atlantic Forest fragments of different sizes and successional stages in the region of Viçosa, MG. This was done by RAPD molecular markers. We observed that the area of the fragments had no effect on the genetic variability of E. nigrita in the direction predicted by meta-population models. Medium-sized well-preserved woods presented the lowest variability, whereas large and small woods were statistically identical. The evidence supports the notion that rural areas present greater dispersal among fragments, implying greater similarity between the populations of fragments located in rural areas when compared to fragments in urban areas.

AMINO ACID-BASED FERTILIZER AS AN ALTERNATIVE TO CALDA VIÇOSA IN ORGANIC AGRICULTURE

Directory of Open Access Journals (Sweden)

Diego Fontebasso Pelizari Pinto

2017-10-01

Full Text Available The aim of this study was to propose a mixture of micronutrients with amino acid-based foliar fertilizer as an alternative to calda viçosa for application in organic agriculture. The study was conducted in two simultaneous trials in an experimental field in Ipeúna, SP, Brazil. The test plant was carioca type dry edible bean cv. Pérola. The treatments in trial 1 were: Control 1 = water; FA = JK® amino acid-based foliar fertilizer; and FA+Mi = FA + CuSO4 + ZnSO4 + MnSO4 + H3BO3. In trial 2, the FA treatment was substituted by calda viçosa (CVi. The treatments were through spray application three times. Dry edible bean leaves were sampled for determination of macronutrient and micronutrient concentrations. Platings of the application rates used in the treatments were performed in the laboratory in a mixture with Bacillus thuringiensis and with Beauveria bassiana to compare the degree of compatibility by means of colony forming units (CFU. The FA+Mi and CVi treatments raised the concentrations of Zn, Cu, and Mn in the leaves. The FA+Mi was compatible, the FA was a stimulant, and the CVi was noxious to B. bassiana and to B. thuringiensis when integrated in the spray mixture.

The importance of neck circumference to thyromental distance ratio (NC/TM) as a predictor of difficult intubation in obstructive sleep apnea (OSA) patients

OpenAIRE

Hala Ezzat Abdel Naim; Sabah Abdel Raouf Mohamed; Sherif Mohamed Soaida; Haitham Hassan Awad Eltrabily

2014-01-01

Background: The trial to find a bedside examination that is helpful for foreseeing difficult intubation is quite inspiring. It was reported that thyromental distance (TM), body mass index (BMI), neck circumference (NC) and a Mallampati score >3 were the only helpful bedside test predictors. By using magnetic resonance imaging, it was established that more fat was present in areas around the collapsible parts of the pharynx in OSA patients. So distribution of fat may provide a better suggestio...

Inclusão digital de jovens na microrregião de Viçosa/Minas Gerais: dimensões políticas e subjetivas | Digital inclusion of youngsters in the Viçosa/Minas Gerais micro region: political and subjective dimensions

Directory of Open Access Journals (Sweden)

Daniela Alves de Alves

2012-04-01

Full Text Available Resumo O presente artigo apresenta resultados de um diagnóstico das implicações das políticas públicas de inclusão digital nas escolas de ensino médio da microrregião de Viçosa. Analisamos a amplitude e os efeitos destas políticas para os jovens da referida região, explorando qualitativamente a dimensão da inclusão, especialmente através da análise dos usos da tecnologia por parte dos jovens considerados incluídos. Constatamos que a inserção dos jovens em políticas de inclusão digital através da escola é limitada e a internet tem sido usada pelos jovens entrevistados predominantemente como espaço de sociabilidade e de pesquisas escolares. O acesso à internet apresenta inúmeras desigualdades. Palavras-chave inclusão digital, internet, rede sociotécnica, jovens, políticas públicas Abstract This article presents results from the diagnosis of the implications of public policies for digital inclusion in secondary schools of the micro-region of Viçosa, Minas Gerais, Brazil. The amplitude and effect of these policies for the youngsters of this region were analyzed, exploring qualitatively the dimensions of the inclusion, especially through the analysis of the uses of technology by the teenagers considered. It could be verified that the insertion of these youngsters in digital inclusion policies at school is limited, and that the Internet has been used by the juveniles interviewed predominantly as a space for sociability and school research. Access to the Internet represents innumerable inequalities. Keywords digital inclusion, internet, socio-technical web, youngsters, public policies

A Robust and Resilient Network Design Paradigm for Region-Based Faults Inflicted by WMD Attack

Science.gov (United States)

2016-04-01

Infrastructure Mapping over Transport Software - Defined Networks (T- SDN )”, IEEE/OSA OFC, 2014 (invited for a special issue of OSA/IEEE JOCN) 23. L. Liu, J...Ji and C. Qiao “Survivable Virtual Infrastructure Mapping with Shared Protection in Transport Software - Defined Networks (T- SDNs )”, OECC, 2014. 25. S...483-493, 2014. 21. Z. Ye, X. Li, A. N. Patel, P. N. Ji, X. Cao, C. Qiao, “Upgrade-aware Virtual Infrastructure Mapping in Software - Defined Elastic

5-years APAP adherence in OSA patients--do first impressions matter?

Science.gov (United States)

van Zeller, Mafalda; Severo, Milton; Santos, Ana Cristina; Drummond, Marta

2013-12-01

Although continuous positive airway pressure (CPAP) is effective in treating obstructive sleep apnoea (OSA), inadequate adherence remains a major cause of treatment failure. This study aimed to determine long term adherence to auto adjusting-CPAP (APAP) and its influencing factors including the role of initial compliance. Eighty-eight male patients with newly diagnosed moderate/severe OSA were included. After initiation of APAP treatment, patients had periodic follow-up appointments at 2 weeks, 6 months and then annually for at least 5 years. Patient's compliance to therapy was assessed in each appointment and predictors to treatment abandonment and poor compliance were evaluated. The studied population had a mean age of 53.8 years and mean apnoea-hypopnoea index of 52.71/h. The mean time of follow-up was 5.2 (± 1.6) years, during that time 22 (25%) patients abandoned APAP, those who maintained treatment had good compliance to it since 94% of them used it more than 4 h/day for at least 70% of days. A significant negative association was found between age, % of days and mean time of APAP use on 12th day and 6th month and the risk of abandoning. APAP use lower than 33% and 57% of days at 12th day and 6th month, respectively had high specificity (≈ 100%) to detect treatment abandonment. the majority of patients adheres to long term APAP treatment and has good compliance after 5-years of follow-up. Age and initial compliance (% days of use and mean hour/day) have the ability to predict future adherence, as soon as 12 days and 6 months after initiation. Copyright © 2013 Elsevier Ltd. All rights reserved.

Invitation Refusals in Cameroon French and Hexagonal French

Science.gov (United States)

Farenkia, Bernard Mulo

2015-01-01

Descriptions of regional pragmatic variation in French are lacking to date the focus has been on a limited range of speech acts, including apologies, requests, compliments and responses to compliments. The present paper, a systematic analysis of invitation refusals across regional varieties of French, is designed to add to the research on…

An invitation to critical mathematics education

DEFF Research Database (Denmark)

Skovsmose, Ole

An Invitation to Critical Mathematics Education deals with a range of crucial topics. Among these are students’ foreground, landscapes of investigation, and mathematics in action. The book is intended for a broad audience: educators, students, teachers, policy makers, anybody interested...... in the further development of mathematics education. The book discusses concerns and preoccupation. This way it provides an invitation into critical mathematics education....

Fewer invited talks by women in evolutionary biology symposia

NARCIS (Netherlands)

Schroeder, J.; Dugdale, H.L.; Radersma, R.; Hinsch, M.; Buehler, D.M.; Saul, J.; Porter, L.; Liker, A.; De Cauwer, I.; Johnson, P. J.; Santure, A. W.; Griffin, A. S.; Bolund, E.; Ross, L.; Webb, T. J.; Feulner, P. G. D.; Winney, I.; Szulkin, M.; Komdeur, J.; Versteegh, M. A.; Hemelrijk, C. K.; Svensson, E. I.; Edwards, H.; Karlsson, M.; West, S. A.; Barrett, E. L. B.; Richardson, D. S.; van den Brink, V.; Wimpenny, J. H.; Ellwood, S. A.; Rees, M.; Matson, K.D.; Charmantier, A.; dos Remedios, N.; Schneider, N. A.; Teplitsky, C.; Laurance, W. F.; Butlin, R. K.; Horrocks, Nicholas

Lower visibility of female scientists, compared to male scientists, is a potential reason for the under-representation of women among senior academic ranks. Visibility in the scientific community stems partly from presenting research as an invited speaker at organized meetings. We analysed the sex

Improving PTSD Symptoms and Preventing Progression of Subclinical PTSD to an Overt Disorder by Treating Comorbid OSA With CPAP.

Science.gov (United States)

Ullah, M I; Campbell, Douglas G; Bhagat, Rajesh; Lyons, Judith A; Tamanna, Sadeka

2017-10-15

Obstructive sleep apnea (OSA) and posttraumatic stress disorder (PTSD) are common in United States veterans. These conditions often coexist and symptoms overlap. Previous studies reported improvement in PTSD symptoms with continuous positive airway pressure (CPAP) therapy for comorbid OSA but its effect has not been assessed in a non-PTSD cohort. We have prospectively assessed the effect of CPAP therapy on clinical symptom improvement as a function of CPAP compliance levels among PTSD and non-PTSD veterans. Veterans in whom OSA was newly diagnosed were enrolled in our study (n = 192). Assignment to PTSD and non-PTSD cohorts was determined by chart review. Each patient completed the military version of the PTSD Checklist (PCL), Epworth Sleepiness Scale (ESS), and reported nightmare frequency (NMF) at baseline and 6 months after CPAP therapy. CPAP adherence was objectively documented from machine compliance data. We had complete data for 177 veterans (PTSD n = 59, non-PTSD n = 118) for analysis. The mean ages were 51.24 years in the PTSD cohort and 52.36 years in the non-PTSD cohort ( P = .30). In the PTSD cohort, the mean total PCL score (baseline = 66.06, post-CPAP = 61.27, P = .004, d = -0.34) and NMF (baseline = 4.61, post-CPAP = 1.49, P = .0001, d = -0.51) decreased after 6 months of CPAP treatment. Linear regression analysis showed that the CPAP compliance was the only significant predictor for these changes among veterans with PTSD (PCL score: P = .033, R 2 = .65; NMF; P = .03, R 2 = .61). Further analysis by CPAP compliance quartiles in this cohort (Q1 = 0% to 25%, Q2 = 26% to 50%, Q3 = 51% to 75%, Q4 > 75%) revealed that mean total PCL score declined in Q2 (change = -3.91, P = .045, d = 0.43), Q3 (change = -6.6, P = .002, d = 0.59), and Q4 (change = -7.94, P = .037, d = 0.49). In the non-PTSD cohort, the PCL score increased despite CPAP therapy in lower CPAP compliance quartiles Q1 (change = 8.71, P = .0001, d = 0.46) and Q2 (change = 4.51, P = .046, d = 0

  Personal invitations for population-based breast cancer screening

DEFF Research Database (Denmark)

Saalasti-Koskinen, Ulla; Mäkelä, Marjukka; Saarenmaa, Irma

2010-01-01

participation free of charge and the benefits of detecting breast cancer early. Harm associated with screening was seldom mentioned; no unit mentioned the possibility of false-negative results or overtreatment. CONCLUSION: The screening units provided very variable information, which often was biased toward......RATIONALE AND OBJECTIVES: Women who are invited for breast cancer screening should get enough information about the benefits and harms of screening to make an informed decision on participation. Personal invitations are an important source of information, because all invited women receive them....... The objective of this study was to evaluate the information breast cancer screening units send to women invited for screening in Finland. MATERIALS AND METHODS: A questionnaire was sent to all breast cancer screening units in Finland in 2005 and 2008, and the information (eg, invitations, results letters...

Specific insomnia symptoms and self-efficacy explain CPAP compliance in a sample of OSAS patients.

Science.gov (United States)

Philip, Pierre; Bioulac, Stéphanie; Altena, Elemarije; Morin, Charles M; Ghorayeb, Imad; Coste, Olivier; Monteyrol, Pierre-Jean; Micoulaud-Franchi, Jean-Arthur

2018-01-01

This study explores the association between specific insomnia symptoms (sleep onset, sleep maintenance and early morning awakenings symptoms) and self-efficacy (perceived self-confidence in the ability to use CPAP) with CPAP compliance in French patients with obstructive sleep apnea syndrome (OSAS). We performed a retrospective, cross-sectional analysis of CPAP compliance in a cohort of 404 patients diagnosed with OSAS. Patients completed mailed questionnaires on sleepiness (ESS), insomnia (ISI) and self-efficacy in sleep apnea (SEMSA). Linear regression modeling analyses were performed to explore the impact of measured variables on the number of hours of CPAP use. Of the initial pool of 404 patients, 288 returned the questionnaires (71% response rate). Their mean age was 63.16±12.73 yrs, 31% were females, mean BMI was 30.39±6.31 kg/m2, mean daily CPAP use was 6.19±2.03 h, mean number of years of use was 6.58±6.03 yrs, and mean initial AHI before CPAP use was 34.61±20.71 /h. Age (pCPAP use. We found that specific insomnia symptoms and self-efficacy were associated with CPAP compliance. Our findings underline the need to demonstrate that interventions that reduce insomnia symptoms and improve self-efficacy will increase CPAP compliance.

Prevalência do complexo teníase-cisticercose na zona rural do município de Viçosa, Minas Gerais Prevalence of Taeniasis-cysticercosis complex in the rural area of Viçosa-MG, Brazil

Directory of Open Access Journals (Sweden)

Adriana Felix Iasbik

2010-07-01

Full Text Available A teníase é uma doença que se manifesta no ser humano em decorrência da presença da forma adulta da Taenia sp., enquanto a cisticercose decorre da infecção pelo estágio larvar da Taenia sp. ou Taenia solium, no caso dos suínos e humanos. Foi realizado um estudo transversal visando a determinar a prevalência de cisticercose em suínos e de teníase em 176 propriedades localizadas na zona rural de Viçosa, Minas Gerais (MG. Foram coletadas amostras de sangue de 226 suínos e fezes de 266 humanos, além da realização de um inquérito epidemiológico. Não foi identificada teníase humana, e a prevalência da cisticercose suína foi de 0,4%. As informações obtidas mostraram que a maioria das pessoas possuía o hábito de consumir carne suína não inspecionada; entretanto, todas as pessoas se alimentavam da carne bem aquecida. Em apenas 1,1% das propriedades, o esgoto era depositado diretamente no solo e em 99,4% destas a água era canalizada, enquanto 88,1% dos suínos eram criados presos. Concluiu-se que, na zona rural do município de Viçosa-MG, a prevalência do complexo teníase-cisticercose foi baixa, mostrando ainda um nível de contaminação inferior ao de outros municípios onde o complexo foi estudado.Taeniasis occurs due to the presence of the adult form of Taenia sp. in human beings, and cysticercosis is caused by the presence of the larval stage of T. solium in pigs and humans. A transversal study was conducted aiming to determine the prevalence of porcine cysticercosis and Taeniasis in 176 farms located in rural areas of Viçosa-MG. Blood samples of 226 pigs, and feces samples of 266 humans were collected. An epidemiological survey has also been done. We found a prevalence of 0.4% of porcine cysticercosis and Taeniasis has not been found. The epidemiological data has shown that although most people consumed non-inspected pork, it used to be prepared well-done. Data showed that 88.1% of the pigs are reared in confinement

Indicadores de campo para solos hidromórficos na região de Viçosa (MG Field indicators for the identification of hydromorphic soils in the region of Viçosa, Minas Gerais - Brazil

Directory of Open Access Journals (Sweden)

C. E. B. Campos

2003-12-01

valores de pE foram mais baixos, embora estes tenham variado entre limites muito amplos. A presença do lençol freático acima de 60 cm foi um bom critério para avaliar o grau de gleização dos solos.Local indicators are useful to identify environments. In the region of Viçosa, Gleysols with their typically gray color are not common, although waterlogged soils under the plant cover "taboa" (Thypha dominguensis are found. Most of the soils with high water tables are covered by "taboa", while the gley characteristics are not pronounced, especially in soils with high iron contents. Since there was no clear relation among the height of the water table, O2 deficiency, and color, it was hypothesized that other types of indicators for reducing conditions could be found in these environments. In pursuit of local indicators, soil, water and vegetation were characterized. Soils with different degrees of drainage limitation were studied in Cajuri (area 1; Viçosa (area 2, and Coimbra (area 3. For a field evaluation of soil redox conditions, pH and pE were measured by an electronic device, adapted to a steel probe. Despite its importance for the identification of environmental indicators, soil morphology was not a precise indicator for O2 deficiency during long periods of time, the most common characteristic of waterlogged soils. Although color is a useful indicator for numerous drainage conditions of the soil, it was not efficient in this area as well. In general, the studied Gleysols presented a chroma > 2, which surpasses the criterion for gley horizons in the Brazilian Soil Classification System. Therefore, soil color was not a good indicator for drainage limitation in these areas. The presence of "taboa" was confirmed as a good indicator for drainage limitation. Pure clusters of this vegetation were found where pH and pE values are low, but vary within a wide range. A water table above 0.60 m was found to be a good indicator for the gley status of soils.

Translation of Berlin Questionnaire to Portuguese language and its application in OSA identification in a sleep disordered breathing clinic

Directory of Open Access Journals (Sweden)

A.P. Vaz

2011-03-01

Full Text Available Background: Berlin Questionnaire (BQ, an English language screening tool for obstructive sleep apnea (OSA in primary care, has been applied in tertiary settings, with variable results. Aims: Development of BQ Portuguese version and evaluation of its utility in a sleep disordered breathing clinic (SDBC. Material and methods: BQ was translated using back translation methodology and prospectively applied, previously to cardiorespiratory sleep study, to 95 consecutive subjects, referred to a SDBC, with OSA suspicion. OSA risk assessment was based on responses in 10 items, organized in 3 categories: snoring and witnessed apneas (category 1, daytime sleepiness (category 2, high blood pressure (HBP/obesity (category 3. Results: In the studied sample, 67.4% were males, with a mean age of 51 ± 13 years. Categories 1, 2 and 3 were positive in 91.6, 24.2 and 66.3%, respectively. BQ identified 68.4% of the patients as being in the high risk group for OSA and the remaining 31.6% in the low risk. BQ sensitivity and specificity were 72.1 and 50%, respectively, for an apnea-hipopnea index (AHI > 5, 82.6 and 44.8% for AHI > 15, 88.4 and 39.1% for AHI > 30. Being in the high risk group for OSA did not infl uence significantly the probability of having the disease (positive likelihood ratio [LR] between 1.44-1.49. Only the items related to snoring loudness, witnessed apneas and HBP/obesity presented a statistically positive association with AHI, with the model constituted by their association presenting a greater discrimination capability, especially for an AHI > 5 (sensitivity 65.2%, specificity 80%, positive LR 3.26. Conclusions: The BQ is not an appropriate screening tool for OSA in a SDBC, although snoring loudness, witnessed apneas, HBP/obesity have demonstrated being significant questionnaire elements in this population. Resumo: Introdução: O Questionário de Berlim (QB, originalmente desenvolvido em língua inglesa como um instrumento de

Challenge, Confrontation, and Exhortation as Intentional Invitations by Professional Helpers.

Science.gov (United States)

Schmidt, John J.

1996-01-01

Examines intentional invitations that challenge, confront, exhort, and persuade people to change their behaviors. Assumes that the sender controls the "intention" and that the receiver determines the degree of "inviting." Suggests that elements of the invitational model serve as a framework to create acceptable inducements in…

[Treatment compliance with continuous positive airway pressure device among adults with obstructive sleep apnea (OSA): how many adhere to treatment?].

Science.gov (United States)

Sarrell, E Michael; Chomsky, Ofer; Shechter, Dalia

2013-03-01

Obstructive sleep apnea syndrome (OSA) afflicts approximately 5% of the adult population and increases with age. The gold standard treatment is with the Continuous Positive Airways Pressure (CPAP) machine. Well-designed prospective trials to elucidate long term compliance with CPAP machine are rare. Assessing compliance and long-term use of CPAP machines among patients with OSA who were referred for treatment with this machine. A 4 years prospective cohort observational study was conducted using telephone interviews of 371 newly diagnosed patients with moderate to severe OSA, who received a specialist recommendation to use the CPAP machine which was bought and adjusted to their use. At the end of the first year, 126 (34%) of the OSA patients used the CPAP machine on a nightly basis (regular users), 120 (32.3%) had not used it at all, and 125 (33.7%) had used it only intermittently. The number of regular users increased between the 1st and 2nd year from 126 (34%), to 163 (44%) (p < 0.07) due to additions from the intermittent users group. The non-users group grew from 120 (32.3%) in the first year, and every year afterwards, up to 221 (59.6%) in the fourth year (p < 0.02). In contrast, there was a significant decrease in the intermittent users group, which declined from 125 (33.7%) in the first year to only 18 (4.8%) in the 4th year (p < 0.005). Most of the patients (92.9%) were males. The average age of the regular users was 59.6 years (+/- 11), which was higher in comparison to 55.9 years (+/- 10.3) for the non-users or 58.9 years (+/- 12.6) among the intermittent users (p = 0.064). There were no statistical differences in co-morbidities or demographics between the three groups. However, the regular users were found to have a higher score in the Epworth Sleepiness Scale (ESS) and a minimal arterial oxygen saturation (SaO2) level lower than the patients in the non-users and intermittent users groups (p = 0.019 and p = 0.03 respectively). Four years follow

A pilot study to compare the cerebral hemodynamics between patients with obstructive sleep apnea syndrome (OSA) and periodic limb movement syndrome (PLMS) during nocturnal sleep with near-infrared spectroscopy (NIRS)

Science.gov (United States)

Zhang, Zhongxing; Schneider, Maja; Laures, Marco; Fritschi, Ursula; Hügli, Gordana; Lehner, Isabella; Qi, Ming; Khatami, Ramin

2014-03-01

Obstructive sleep apnea syndrome (OSA) and periodic limb movement in sleep syndrome (PLMS) are two common sleep disorders. Previous studies showed that OSA and PLMS share common features, such as increased cardio-vascular risk, both apnea events and limb movements occur periodically, they are usually associated with cortical arousals, and both of them can induce declines in peripheral oxygen saturation measured with pulse oximetry. However, the question whether apnea events and limb movements also show similar characteristics in cerebral hemodynamic and oxygenation has never been addressed. In this pilot study, we will first time compare the cerebral hemodynamic changes induced by apnea events and limb movements in patients with OSA (n=4) and PLMS (n=4) with NIRS. In patients with OSA, we found periodic oscillations in HbO2, HHb, and blood volume induced by apnea/hypopnea events, HbO2 and HHb showed reverse changing trends. By contrast, the periodic oscillations linked to limb movements were only found in HbO2 and blood volume in patients with PLMS. These findings of different cerebral hemodynamics patterns between apnea events and limb movements may indicate different regulations of nervous system between these two sleep disorders.

48 CFR 52.232-31 - Invitation To Propose Financing Terms.

Science.gov (United States)

2010-10-01

... Financing Terms. 52.232-31 Section 52.232-31 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.232-31 Invitation To Propose Financing Terms. As prescribed in 32.205(b) and 32.206, insert the following provision: Invitation To Propose Financing Terms (OCT 1995) (a) The offeror is invited to propose...

Textbook Images: How Do They Invite Students into Physics?

Science.gov (United States)

Bungum, Berit

2013-01-01

This paper presents a study of images in Norwegian physics textbooks for upper secondary school, and how they invite students into physics by means of visual communication. The concept of "framing" is used to investigate how the perspective in the image provides a sense of participation. It is found that older textbooks, where objects…

Functional MRI of the pharynx in obstructive sleep apnea (OSA) with rapid 2-D flash sequences

International Nuclear Information System (INIS)

Jaeger, L.; Guenther, E.; Gauger, J.; Nitz, W.; Kastenbauer, E.; Reiser, M.

1996-01-01

Functional imaging of the pharynx used to be the domain of cineradiography, CT and ultrafast CT. The development of modern MRI techniques led to new access to functional disorders of the pharynx. The aim of this study was to implement a new MRI technique to examine oropharyngeal obstructive mechanisms in patients with obstructive sleep apnea (OSA). Sixteen patients suffering from OSA and 6 healthy volunteers were examined on a 1.5 T whole-body imager ('Vision', Siemens, Erlangen Medical Engineering, Germany) using a circular polarized head coil. Imaging was performed with 2D flash sequences in midsagittal and axial planes. Patients and volunteers were asked to breathe normally through the nose and to simulate snoring and the Mueller maneuver during magnetic resonance imaging (MRI). Prior to MRI, all patients underwent an ear, nose and throat (ENT) examination, functional fiberoptic nasopharyngoscopy and polysomnography. A temporal resolution of 6 images/s and an in-plane resolution of 2.67x1.8 mm were achieved. The mobility of the tongue, soft palate and pharyngeal surface could be clearly delineated. The MRI findings correlated well with the clinical examinations. We propose ultrafast MRI as a reliable and non-invasive method of evaluating pharyngeal obstruction and their levels. (orig.) [de

A Survey of Phenomena in Ionized Gases. Invited Papers. A Collection of Invited Papers Presented at the Eighth International Conference on Phenomena in Ionized Gases

International Nuclear Information System (INIS)

1968-01-01

Invited review papers from the Proceedings of the Eighth Conference on Phenomena in Ionized Gases, which was organized by the Technische Hochschule Wien and the Österreichische Studiengesellschaft für Atomenergie, and held in Vienna, 27 August - 2 September 1967. The IAEA and the International Union of Pure and Applied Physics supported the organizers. Contents: Introductory papers (3 papers); Collision processes (4 papers); Waves and beams in plasmas (6 papers); Surface phenomena (3 papers); Lasers (3 papers); Low pressure discharges (1 paper); Selected topics in plasma physics (2 papers); High pressure discharges (3 papers); Probe techniques and theory (4 papers); Basic data and fundamental plasma processes (4 papers); Summary (1 paper). Each paper is in its original language (20 English, 3 French, 9 Russian and 2 German) and is preceded by an abstract in English, with a second one in the original language if this is not English. (author)

Invitation to Speak at a Conference: The Tempting Technique Adopted by Predatory Conferences' Organizers.

Science.gov (United States)

Asadi, Amin

2018-03-08

In recent years, predatory journals, conferences, and publishers have turned to an inevitable threat in scientific publishing. Researchers, regardless of their disciplines, should be aware of these predators and have to be able to recognize them. The main aim of the present paper is to raise awareness about the growing menace of fake invitations to speak at a scientific conference organized by predatory organizers and publishers. Some subtle signs to identify the fake invitations from the authentic ones have been introduced and discussed.

CPAP Adherence is Associated With Attentional Improvements in a Group of Primarily Male Patients With Moderate to Severe OSA.

Science.gov (United States)

Deering, Sean; Liu, Lin; Zamora, Tania; Hamilton, Joanne; Stepnowsky, Carl

2017-12-15

Obstructive sleep apnea (OSA) is a widespread condition that adversely affects physical health and cognitive functioning. The prevailing treatment for OSA is continuous positive airway pressure (CPAP), but therapeutic benefits are dependent on consistent use. Our goal was to investigate the relationship between CPAP adherence and measures of sustained attention in patients with OSA. Our hypothesis was that the Psychomotor Vigilance Task (PVT) would be sensitive to attention-related improvements resulting from CPAP use. This study was a secondary analysis of a larger clinical trial. Treatment adherence was determined from CPAP use data. Validated sleep-related questionnaires and a sustained-attention and alertness test (PVT) were administered to participants at baseline and at the 6-month time point. Over a 6-month time period, the average CPAP adherence was 3.32 h/night (standard deviation [SD] = 2.53), average improvement in PVT minor lapses was -4.77 (SD = 13.2), and average improvement in PVT reaction time was -73.1 milliseconds (standard deviation = 211). Multiple linear regression analysis showed that higher CPAP adherence was significantly associated with a greater reduction in minor lapses in attention after 6 months of continuous treatment with CPAP therapy (β = -0.72, standard error = 0.34, P = .037). The results of this study showed that higher levels of CPAP adherence were associated with significant improvements in vigilance. Because the PVT is a performance-based measure that is not influenced by prior learning and is not subjective, it may be an important supplement to patient self-reported assessments. Name: Effect of Self-Management on Improving Sleep Apnea Outcomes, URL: https://clinicaltrials.gov/ct2/show/NCT00310310, Identifier: NCT00310310. © 2017 American Academy of Sleep Medicine

Gender parity trends for invited speakers at four prominent virology conference series.

Science.gov (United States)

Kalejta, Robert F; Palmenberg, Ann C

2017-06-07

speakers at international scientific conferences exemplifies a present-day discussion topic usually occurring without facts to support or refute the arguments. We now provide records profiling four prominent virology conferences over the years 1982 to 2017 with the intention that the trends and accompanying analyses of the gender parity of invited speakers may allow the ongoing discussions to be informed. Copyright © 2017 American Society for Microbiology.

Initiation of CPAP therapy for OSA: does prophylactic humidification during CPAP pressure titration improve initial patient acceptance and comfort?

Science.gov (United States)

Wiest, G H; Harsch, I A; Fuchs, F S; Kitzbichler, S; Bogner, K; Brueckl, W M; Hahn, E G; Ficker, J H

2002-01-01

Heated humidifiers (HH) enable effective treatment of upper airway dryness during nasal continuous positive airway pressure (nCPAP) therapy for obstructive sleep apnoea (OSA), but the role of prophylactic use of HH during the initiation of nCPAP treatment has not been studied so far. The aim of the present study was to investigate whether prophylactic HH during the initiation of CPAP would result in improved initial patient comfort and acceptance. In 44 consecutive, previously untreated OSA patients with no history of upper airway dryness, CPAP titration with and without HH was performed on two consecutive nights in a randomised order. The patients were interviewed after each treatment night in order to establish the comfort of the treatment, and, after the second treatment, they were asked which of the two nights they considered more pleasant, and which treatment they would prefer for long-term use. Following CPAP titration with HH, 32 patients (73%) claimed to have had a better night's sleep than usual (i.e. without CPAP treatment) compared with 33 patients (75%) saying the same following CPAP treatment without HH. For 21 patients (47.7%) treatment with HH was more pleasant, 23 (52.3%) saw no difference or said that treatment without HH was more pleasant. Nineteen patients (43.2%) gave preference to treatment with HH for long-term use, while 25 patients (56.8%) had no preference or said they would prefer treatment without HH. The use of HH during the initiation phase of CPAP treatment was associated neither with an initial improvement in comfort nor with greater initial treatment acceptance. Copyright 2002 S. Karger AG, Basel

Creating intentionally inviting schools through professional development: an appreciative inquiry

Directory of Open Access Journals (Sweden)

G.M. Steyn

2010-07-01

Full Text Available The professional development (PD of teachers plays an important role in schools; it is indispensable for continuous school development. When schools are exposed to new approaches to learning and teaching, teachers are granted the opportunities to change their thinking and behaviour. In 2009, two South African schools with specific inviting characteristics were nominated for the inviting school award given by the International Alliance for Invitational Education (IAIE. However, the inviting characteristics of these schools were not explicitly intentional according to the IE philosophy, therefore they had to follow a professional development programme aimed at raising teachers’ awareness of invitational education (IE. Workshops were held to equip staff members with IE knowledge and skills, and to increase their understanding of their current practices with a view of making them more intentionally inviting. The study focused on the following two questions: What are the positive experiences of teaching staff concerning the current approach to teaching and learning in schools?; and What strategies may be introduced to assist teachers and their schools in becoming intentionally inviting? These two questions are based on appreciative inquiry (AI and IE. A qualitative research design was most appropriate for the purpose of this study. An analysis of the data revealed two categories (the discovery phase: discovering the best of what exists in the school and the dreaming phase: creating a new future on which AI is based.

Invitation to Speak at a Conference: The Tempting Technique Adopted by Predatory Conferences’ Organizers

DEFF Research Database (Denmark)

Asadi, Amin

2018-01-01

In recent years, predatory journals, conferences, and publishers have turned to an inevitable threat in scientific publishing. Researchers, regardless of their disciplines, should be aware of these predators and have to be able to recognize them. The main aim of the present paper is to raise awar...... awareness about the growing menace of fake invitations to speak at a scientific conference organized by predatory organizers and publishers. Some subtle signs to identify the fake invitations from the authentic ones have been introduced and discussed....

Reflexiones sobre la protección del consumidor de servicios turísticos frente a la publicidad engañosa de sociedades mercantiles turísticas

OpenAIRE

Barrero Rodríguez, Enrique; Viguera Revuelta, Rodrigo; Jiménez Caballero, José Luis (Coordinador)

2016-01-01

En la presente Comunicación, sus autores pretenden exponer la situación en la que los potenciales clientes de las empresas turísticas pueden sufrir engaños como consecuencia de la publicidad engañosa. En tales supuestos, el mercado se suele caracterizar por el uso de una determinada publicidad que pretende incidir en la voluntad del consumidor, de manera que la actividad publicitaria se muestra como realmente relevante y decisiva para la formación de la voluntad de los ref...

The importance of neck circumference to thyromental distance ratio (NC/TM as a predictor of difficult intubation in obstructive sleep apnea (OSA patients

Directory of Open Access Journals (Sweden)

Hala Ezzat Abdel Naim

2014-07-01

Conclusion: Difficult intubation in OSA obese patients was independently associated with a Mallampati score of III or IV, and NC/TM ⩾5.15. Moreover, NC/TM yielded a high sensitivity, specificity and a negative predictive value.

Sismos y lluvias, factores detonantes de deslizamientos de laderas en las regiones montañosas de Puebla, México

Directory of Open Access Journals (Sweden)

Oscar A. Cuanalo C.

2006-01-01

Full Text Available El estado de Puebla ubicado en el centro de la República Mexicana, se ve afectado por sismos producto de la actividad a lo largo del Cinturón Volcánico Mexicano que tienen impacto en el centro y sur del estado, además de lluvias intensas en las regiones montañosas ubicadas al Norte y Nororiente del mismo, originadas por los huracanes y tormentas tropicales procedentes del Golfo de México. El escenario anterior ofrece peculiaridades de tipo geomorfológico y meteorológico que han desencadenado deslizamientos de laderas, los cuales han causado considerables daños económicos y lamentables pérdidas humanas. En este artículo se describe brevemente las características geomorfológicas del estado de Puebla, considerando su clima, el cual tiene impacto en la meteorización de las rocas que conforman la región montañosa; además se incluye su historia sismológica en los últimos 100 años, para eventos mayores de 6° Richter, y las lluvias torrenciales de 1999 y 2005 que han desencadenado deslizamientos de laderas

Sistemas de classificações geotécnicas de solos: estudo de caso aplicado à rodovia não pavimentada vcs 346, Viçosa, MG Geotechnical soil classification systems: case study applied to the vcs 346 unpaved road, Viçosa, MG

Directory of Open Access Journals (Sweden)

Taciano Oliveira da Silva

2010-04-01

Full Text Available Este artigo aborda uma contribuição às classificações geotécnicas tradicionais de solos Unified Soil Classification System (USC, Transportation Research Board System (TRB e a Metodologia Miniatura, Compactado, Tropical (MCT para um caso aplicado à rodovia municipal não pavimentada VCS 346, no Município de Viçosa, MG, considerando-se várias amostras deformadas de solos coletadas no subleito da referida via. Os principais objetivos deste estudo residem na contribuição de um banco de dados geotécnicos sobre classificações de solos tropicais, bem como na verificação de possíveis agrupamentos entre os sistemas geotécnicos tradicionais de classificação e a metodologia MCT. O programa de laboratório envolveu a realização dos seguintes ensaios: (i granulometria conjunta; (ii limites de Atterberg (LL e LP; (iii massa específica dos grãos do solo; (iv compactação Mini-MCV; e (v perda de massa do corpo-de-prova por imersão em água. Os resultados possibilitaram verificar que, após a classificação das amostras, vários agrupamentos entre os sistemas de classificações geotécnicas tradicionais coincidiram com aqueles já apresentados na metodologia MCT e, considerando a pedogênese da região de Viçosa, MG, para o grupo NG', houve a contribuição dos grupos SC, SM e CL do Sistema USC e do grupo A-4 do Sistema TRB.This paper addresses a contribution to the traditional geotechnical soil classifications systems USC (Unified Soil Classification and TRB (Transportation Research Board, and the MCT methodology (Miniature, Compacted, Tropical applied to a case study involving the laboratory geotechnical characterization of disturbed samples from the subgrade of the VCS 346 municipal unpaved road, located in Viçosa - MG. The main goals of this study are to contribute to the formation of a database directed to the geotechnical classification of tropical soils as well as to verify possible groupings among the traditional

8th international workshop on plasma edge theory in fusion devices. Abstracts of invited and contributed papers

International Nuclear Information System (INIS)

Sipilae, S.K.; Heikkinen, J.A.

2001-01-01

The 8th International Workshop on Plasma Edge Theory in Fusion Devices, held at Dipoli Congress Centre, Espoo, Finland, is organised on behalf of the International Scientific Committee by Helsinki University of Technology and VTT (Technical Research Centre of Finland). Similar to the seven preceding Workshops, it addresses the theory for the boundary layer of magnetically confined fusion plasmas. It reflects the present status of the theory for the edge region of fusion plasmas. Emphasis is placed on the development of theory and of appropriate numerical methods as well as on self-consistent modelling of experimental data (including also empirical elements). The following topics are covered: basic edge plasma theory, models of special phenomena and edge control, and integrated edge plasma modelling. The International Scientific Committee has selected the papers and compiled the scientific programme. All other arrangements have been made by the Local Organising Committee. The Workshop is supported by the European Commission, High-Level Scientific Conferences. This Book of Abstracts contains the scientific programme and the abstracts of the invited and contributed papers. The Workshop has seven invited lectures of 60 minutes duration (including 10 minutes for discussion). In addition, 10 contributed papers were selected for oral presentation of 30 minutes duration (including five minutes for discussion). All oral presentations are given in plenary sessions. The remaining 34 contributed papers are presented as posters in three sessions. The invited lectures and contributed oral papers are presented also as posters. All invited and contributed papers will be refereed and published also as a regular issue of the journal Contributions to Plasma Physics. (orig.)

Invitation and Evaluation of Bids for Nuclear Power Plants

International Nuclear Information System (INIS)

2011-01-01

This publication emphasizes the integrity and interdependence of various activities related to the bid invitation, technical and economic evaluation and contracting, it updates information included in the existing IAEA documents in order to better reflect the developments in the nuclear and energy industry, compiles a more compact and user friendly guidebook integrating the existing IAEA documents on the subject. It provides the necessary information to organize, guide and realize the activities related to the invitation, the technical and economic evaluation of bids, and contracting as an integrated process. Furthermore, this publication indicates how and to what degree the activities preceding the preparation of the bid invitation specification, the evaluation of bids and contracting could influence the process.

INVITATION FROM THE UBS

CERN Multimedia

UBS SA

2000-01-01

Via its Web pages (http://www.ubs.com), the UBS offers you direct access to all its telebanking services, namely:information relating to accounts and custody accounts (balances, debits and credits);stock market information and placing of orders;domestic and foreign payment transactions.These supplementary and inexpensive banking services mean that you no longer have to go to the bank to obtain the information you require and are not therefore limited by bank opening times.The UBS will be holding two sessions on the CERN site to present this modern product on:25.4.2000 (in French),26.4.2000 (in English).The agenda will be as follows:12.00 to 12.40 p.m.Presentation of the product;12.40 to 13.10 p.m.Question-and-answer session;13.10 to 14.00 p.m.Buffet and discussions.To enable us to meet your requirements and to expedite matters, we invite you to register for one of these sessions by sending an e-mail or letter to:pierre.guyenon@ubs.com before 7.4.2000 indicating:your surname and first name, the account number(...

Effect of CPAP on Cardiac Function in Minimally Symptomatic Patients with OSA: Results from a Subset of the MOSAIC Randomized Trial.

Science.gov (United States)

Craig, Sonya; Kylintireas, Ilias; Kohler, Malcolm; Nicoll, Debby; Bratton, Daniel J; Nunn, Andrew J; Leeson, Paul; Neubauer, Stefan; Stradling, John R

2015-09-15

Minimally symptomatic obstructive sleep apnea (OSA) is highly prevalent, and the effects of continuous positive airway pressure (CPAP) on myocardial function in these patients are unknown. The MOSAIC randomized, controlled trial of CPAP for minimally symptomatic OSA assessed the effect of CPAP on myocardial function in a subset of patients. Two centers taking part in the MOSAIC trial randomized 238 patients in parallel to 6 months of CPAP (120) or standard care (118). Of these, 168 patients had echocardiograms, and 68 patients had a cardiac magnetic resonance scan (CMR). A larger group (314) from 4 centers had brain natriuretic peptide (BNP) measured. Mean (SD) baseline oxygen desaturation index (ODI) and Epworth sleepiness score (ESS) were 13.5 (13.2), and 8.4 (4.0), respectively. CPAP significantly reduced ESS and ODI. Baseline LV ejection fraction (LVEF) was well preserved (60.4%). CPAP had no significant effect on echo-derived left atrial (LA) area (-1.0 cm2, 95% CI -2.6 to +0.6, p = 0.23) or early to late left ventricular filling velocity (E/A) ratio (-0.01, 95% CI -0.07 to +0.05, p = 0.79). There was a small change in echo-derived LV end diastolic volume (EDV) with CPAP (-5.9 mL, 95% CI -10.6 to -1.2, p = 0.015). No significant changes were detected by CMR on LV mass index (+1.1 g/m(2), 95% CI -5.9 to +8.0, p = 0.76) or LVEF (+0.8%, 95% CI -1.2 to +2.8, p = 0.41). CPAP did not affect BNP levels (p = 0.16). Six months of CPAP therapy does not change cardiac functional or structural parameters measured by echocardiogram or CMR in patients with minimally symptomatic mild-to-moderate OSA. ISRCTN 34164388 (http://isrctn.org). © 2015 American Academy of Sleep Medicine.

Do Worlds Have Corners? When Children's Picture Books Invite Philosophical Questions

Science.gov (United States)

Maagero, Eva; Ostbye, Guri Lorentzen

2012-01-01

In this article, we want to present and analyse the picture book "The World has no Corners" (2006/1999) by the Norwegian author and illustrator Svein Nyhus. The book represents a new trend in Norwegian picture books for children by inviting the readers into a world of thinking and wondering about existential topics such as life and death, growing…

Preventive home visits to older home-dwelling people in Denmark: are invitational procedures of importance?

DEFF Research Database (Denmark)

Ekmann, A; Vass, M; Avlund, K

2010-01-01

Since 1998 all municipalities in Denmark have been required by law to offer two annual preventive home visits to all home-dwelling citizens aged 75 or over. The influence of invitational procedures on acceptance rates has not been investigated. The aim of this study was to describe and investigate...... whether different invitational procedures were associated with first preventive home visit acceptance rates. The study was based on secondary analyses of data from the Danish Intervention Study on Preventive Home Visits. Data were collected from 1998 to 2002. Of the 4060 participants in the main study......, 3245 reported receiving an offer for an identifiable preventive home visit, of whom 2399 (73.9%) provided complete data for the main analyses in the present study. Invitational procedures were categorised as: (1) a letter with a proposed date and time for the visit, (2) a visitor telephone call, and (3...

In patients with minimally symptomatic OSA can baseline characteristics and early patterns of CPAP usage predict those who are likely to be longer-term users of CPAP.

Science.gov (United States)

Turnbull, Christopher D; Bratton, Daniel J; Craig, Sonya E; Kohler, Malcolm; Stradling, John R

2016-02-01

Long-term continuous positive airway pressure (CPAP) usage varies between individuals. It would be of value to be able to identify those who are likely to benefit from CPAP (and use it long term), versus those who would not, and might therefore benefit from additional help early on. First, we explored whether baseline characteristics predicted CPAP usage in minimally symptomatic obstructive sleep apnoea (OSA) patients, a group who would be expected to have low usage. Second, we explored if early CPAP usage was predictive of longer-term usage, as has been shown in more symptomatic OSA patients. The MOSAIC trial was a multi-centre randomised controlled trial where minimally symptomatic OSA patients were randomised to CPAP, or standard care, for 6 months. Here we have studied only those patients randomised to CPAP treatment. Baseline characteristics including symptoms, questionnaires [including the Epworth sleepiness score (ESS)] and sleep study parameters were recorded. CPAP usage was recorded at 2-4 weeks after initiation and after 6 months. The correlation and association between baseline characteristics and 6 months CPAP usage was assessed, as was the correlation between 2 and 4 weeks CPAP usage and 6 months CPAP usage. One hundred and ninety-five patients randomised to CPAP therapy had median [interquartile range (IQR)] CPAP usage of 2:49 (0:44, 5:13) h:min/night (h/n) at the 2-4 weeks visit, and 2:17 (0:08, 4:54) h/n at the 6 months follow-up visit. Only male gender was associated with increased long-term CPAP use (male usage 2:56 h/n, female 1:57 h/n; P=0.02). There was a moderate correlation between the usage of CPAP at 2-4 weeks and 6 months, with about 50% of the variability in long-term use being predicted by the short-term use. In patients with minimally symptomatic OSA, our study has shown that male gender (and not OSA severity or symptom burden) is associated with increased long-term use of CPAP at 6 months. Although, in general, early patterns of CPAP

Preventive home visits to older home-dwelling people in Denmark: are invitational procedures of importance?

Science.gov (United States)

Ekmann, A; Vass, M; Avlund, K

2010-11-01

Since 1998 all municipalities in Denmark have been required by law to offer two annual preventive home visits to all home-dwelling citizens aged 75 or over. The influence of invitational procedures on acceptance rates has not been investigated. The aim of this study was to describe and investigate whether different invitational procedures were associated with first preventive home visit acceptance rates. The study was based on secondary analyses of data from the Danish Intervention Study on Preventive Home Visits. Data were collected from 1998 to 2002. Of the 4060 participants in the main study, 3245 reported receiving an offer for an identifiable preventive home visit, of whom 2399 (73.9%) provided complete data for the main analyses in the present study. Invitational procedures were categorised as: (1) a letter with a proposed date and time for the visit, (2) a visitor telephone call, and (3) a letter with encouragement to phone the visitor for appointment (letter without a proposed date). Covariates included sex, age, experience with preventive interventions, functional ability, self rated health, social relations and psychosocial characteristics. Statistical analyses included chi-square tests, and bi- and multivariable logistic regression analyses. Different invitational procedures were associated with first preventive home visit acceptance rates. Significantly more men (75.1%) than women (62.8%) declined the first preventive home visit regardless of the invitational procedure. Compared to 'letter with a proposed date', men had an odds ratio of 1.78 (95% CI: 1.16-2.74) for declining visits when 'telephone call' was used and an odds ratio 2.81 (95% CI: 1.79-4.40) when 'letter without a proposed date' was used as the invitational procedure. In women the odds ratios were 1.23 (95% CI: 0.91-1.68) and 1.87 (95% CI: 1.37-2.55), respectively. © 2010 Blackwell Publishing Ltd.

14 CFR 11.75 - Does FAA invite public comment on petitions for rulemaking?

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Does FAA invite public comment on petitions... Rulemaking and for Exemption § 11.75 Does FAA invite public comment on petitions for rulemaking? Generally, FAA does not invite public comment on petitions for rulemaking. ...

Invitation strategies and coverage in the population-based cancer screening programmes in the European Union.

Science.gov (United States)

Vale, Diama B; Anttila, Ahti; Ponti, Antonio; Senore, Carlo; Sankaranaryanan, Rengaswamy; Ronco, Guglielmo; Segnan, Nereo; Tomatis, Mariano; Žakelj, Maja P; Elfström, Klara M; Lönnberg, Stefan; Dillner, Joakim; Basu, Partha

2018-03-21

The aim of this study was to describe the compliance of the population-based cancer screening programmes in the European Union Member States to the invitation strategies enumerated in the European Guidelines and the impact of such strategies on the invitational coverage. Experts in screening programme monitoring from the respective countries provided data. Coverage by invitation was calculated as the proportion of individuals in the target age range receiving a screening invitation over the total number of annualized eligible population. The invitation strategies of 30 breasts, 25 cervical and 27 colorectal national or regional population-based screening programmes are described. Individual mail invitations are sent by 28 breasts, 20 cervical and 25 colorectal screening programmes. Faecal occult blood test kits are sent by post in 17 of the colorectal cancer screening programmes. The majority of programmes claimed to have a population registry, although some use health insurance data as the database for sending invitations. At least 95% invitation coverage was reached by 16 breast, six cervical and five colorectal screening programmes. Majority of the programmes comply with the invitation strategies enumerated in the European guidelines, although there is still scope for improvements. Coverage by invitation is below the desirable level in many population-based cancer screening programmes in European Union.

Invitation to View Method with Advantages and Disadvantages

Directory of Open Access Journals (Sweden)

Selçuk BUYRUKOĞLU

2018-01-01

Full Text Available Taxpayers and tax administrators sometimes may experience tax dispute. These disputes may arise from the taxpayers as well as from the tax administrators. In resolving tax disputes, tax administrators and tax payers are the first, usually administratively, solution. Because while the tax revenues of the state are possible entered into the state treasury, the taxpayers will benefit from the advantages of administrative solutions. The state and taxpayer herein will be the winner. Invitation to view is one of the administrative remedies for tax disputes. With this practice taxpayers who have caused tax evasion penalty are invited by tax administrators to make a declaration on the condition that the tax examination of the tax disputes is not started and the dispatch process has not been done to the discretion comission. In this study, advantages and disadvantages will be addressed after the definition, legal support, purpose, scope and mechanism of Invitation to view.

Young Women's Experiences of Resisting Invitations to Use Illicit Drugs

Science.gov (United States)

Koehn, Corinne V.; O'Neill, Linda K.

2011-01-01

Ten young women were interviewed regarding their experiences of resisting invitations to use illicit drugs. Hermeneutic phenomenology was used to gather and analyze information. One key theme was the motivations that inspired women to refuse drug offers. Young women resisted drug invitations because of their desires to be authentic, protect their…

Berger Peter L., Invitation à la sociologie

Directory of Open Access Journals (Sweden)

Nicolas Marquis

2011-03-01

Full Text Available L’invitation à la sociologie de Peter Berger est la réédition d’un ouvrage initiale­ment paru en 1963. Né en 1929, P. Berger est un des grands noms de la sociologie amé­ricaine actuelle, notamment connu chez nous pour un ouvrage coécrit avec Th. Luck­­mann et paru trois ans après la première édition de Invitation à la sociologie : The Social Construction of Reality, qui constitue une étape importante dans l’approche dite du constructivisme social en réactivant la tradition phénoménologique en...

Impact of CPAP on activity patterns and diet in patients with obstructive sleep apnea (OSA).

Science.gov (United States)

Batool-Anwar, Salma; Goodwin, James L; Drescher, Amy A; Baldwin, Carol M; Simon, Richard D; Smith, Terry W; Quan, Stuart F

2014-05-15

Patients with severe OSA consume greater amounts of cholesterol, protein, and fat as well as have greater caloric expenditure. However, it is not known whether their activity levels or diet change after treatment with CPAP. To investigate this issue, serial assessments of activity and dietary intake were performed in the Apnea Positive Pressure Long-term Efficacy Study (APPLES); a 6-month randomized controlled study of CPAP vs. sham CPAP on neurocognitive outcomes. Subjects were recruited into APPLES at 5 sites through clinic encounters or public advertisement. After undergoing a diagnostic polysomnogram, subjects were randomized to CPAP or sham if their AHI was ≥ 10. Adherence was assessed using data cards from the devices. At the Tucson and Walla Walla sites, subjects were asked to complete validated activity and food frequency questionnaires at baseline and their 4-month visit. Activity and diet data were available at baseline and after 4 months treatment with CPAP or sham in up to 231 subjects (117 CPAP, 114 Sham). Mean age, AHI, BMI, and Epworth Sleepiness Score (ESS) for this cohort were 55 ± 13 [SD] years, 44 ± 27 /h, 33 ± 7.8 kg/m(2), and 10 ± 4, respectively. The participants lacking activity and diet data were younger, had lower AHI and arousal index, and had better sleep efficiency (p Level of adherence defined as hours of device usage per night at 4 months was significantly higher among men in CPAP group (4.0 ± 2.9 vs. 2.6 ± 2.6). No changes in consumption of total calories, protein, carbohydrate or fat were noted after 4 months. Except for a modest increase in recreational activity in women (268 ± 85 vs. 170 ± 47 calories, p increase in recreational activity in women, OSA patients treated with CPAP do not substantially change their diet or physical activity habits after treatment. .

Impaired sustained attention and lapses are present in patients with mild obstructive sleep apnea.

Science.gov (United States)

Luz, Gabriela Pontes; Guimarães, Thais Moura; Weaver, Terri E; Nery, Luiz E; E Silva, Luciana Oliveira; Badke, Luciana; Coelho, Glaury; Millani-Carneiro, Aline; Tufik, Sergio; Bittencourt, Lia

2016-05-01

Severe obstructive sleep apnea (OSA) directly affects the quality of life, mood, and sustained attention of individuals, but it has not yet been established in the literature, if these changes also affect patients with mild OSA. The purpose of this study was to investigate such negative effects on the parameters described above. A controlled study was held at the Universidade Federal de Sao Paulo, Department of Psychobiology. Thirty-nine mild OSA patients and 25 controls were included. Volunteers could be of both genders with body mass index (BMI) ≤35 kg/m(2) and age between 18 and 65 years. Both groups were subjected to full-night polysomnography (PSG), the subjective assessment of mood (Beck Inventory of Anxiety and Depression), Functional Outcomes of Sleep Questionnaire (FOSQ), and the psychomotor vigilance task (PVT) five times during the day. We considered mild OSA patients those with apnea-hypopnea index (AHI) score between 5 and 15. The control group included subjects with AHI scores attention lapses compared with normal subjects.

Prevalence of obstructive sleep apnea in surgical patients presenting to a tertiary care teaching hospital in India: A preliminary study

Directory of Open Access Journals (Sweden)

Sanjay Agrawal

2013-01-01

Full Text Available Background: Obstructive sleep apnea (OSA is often not diagnosed in patients presenting for surgical procedures thereby increasing the incidence of adverse perioperative course. Early diagnosis of this disease is important in modifying anesthetic management as well as utilizing specific means which may decrease the complications and improve the patient outcome. Methods: Patients greater than eighteen years of age, ASA I-III scheduled for elective surgical procedures under anesthesia were randomly selected. Their demographic data, diagnosis and nature of surgery were noted in a semi-structured performa. They were then screened for the presence of OSA with the help of a STOP BANG questionnaire. Results : This study included two hundred four patients randomly selected. Slight female predominance was seen in this sample (55.4%. Mean age of the subjects was 42.7 years (SD=15.08. 24.5% subjects were at high risk for OSA (STOP-BANG>3 with a male predominance (72% versus 37% in low risk group; X 2 =18.62; P<0.001. High risk OSA subjects had higher prevalence of cardiovascular risk factors (57% vs. 11.7% in low risk group; X 2 =33.35; P<0.001. Similarly, this group had a higher prevalence of asthma and chronic obstructive pulmonary disease (COPD (14% versus 3.8% in low risk group; X 2 =6.54; P=0.03. Prevalence of diabetes mellitus (22% and hypothyroidism (6% was also higher in this group (5.2% and 1.9% in low risk group respectively; X 2 =15.42; P<0.001. Conclusion : High degree of suspicion and knowledge of association of OSA and medical diseases may help in detection of such cases and decrease the rate of perioperative complications thus improving patients safety.

Invitation

CERN Multimedia

2004-01-01

Monday, 11 October Gala-Concert to celebrate 50 years of CERN Jack Liebeck (violin) and Katya Apekisheva (piano) Works by C. Debussy, S. Prokofiev, and L. van Beethoven CERN, Main Auditorium, 20:00 For CERN staff and their families With the assistance of PPARC (UK) Free tickets available at the CERN Press Office (50-1-048). Maximum four tickets per person. For more information on the performers, see: http://www.jackliebeck.com/CERN50/JL.htm http://www.jackliebeck.com/CERN50/KA.htm The "WIENER SCHUBERTBUND" celebrates CERN's 50th "DEUTSCHE MESSE" By Franz Schubert performed by the "WIENER SCHUBERTBUND" On the occasion of the Organization's Fiftieth Anniversary, Mr Hans-Walter Gérard Schober, Honorary Consul-General of Austria in Geneva, is pleased to invite all those working at CERN to a mass at which Franz Schubert's German Mass will be sung by the Vienna Schubert Choral Society. This renown men's choir, founded in 1863. Eminent composers, including Richard Strauss, Wilhelm Kinzel, a...

A Suggestion for Restoring Public Support for Public Schools: Learn to Invite Patrons.

Science.gov (United States)

Roebuck, Flora N.; Russell, Gene; Wedel, Mack

1998-01-01

Proposes that the increasing disavowal of public schools results from experience with day-by-day disinviting behaviors. The suggested remedy is for educators to evaluate their on-the-job responses to their patrons. Wherever subminimal interpersonal conditions are identified, participants should learn to invite people to education. Presents a case…

Composición de especies leñosas en comunidades invadidas en montañas del centro de Argentina: su relación con factores ambientales locales

Directory of Open Access Journals (Sweden)

Sebastián R. Zeballos

2014-12-01

Full Text Available En todo el mundo, las invasiones de especies leñosas exóticas están amenazando las funciones ecosistémicas. La dispersión y el subsecuente reemplazo de bosques de especies nativas por comunidades dominadas por exóticas es evidente, particularmente, en proximidad a centros urbanos donde la presión de propágulos de especies exóticas es alta. Sin embargo, existe una falta de información sobre los factores ambientales que subyacen este reemplazo. En este estudio nos propusimos responder las siguientes preguntas: (1 ¿se observa una segregación espacial a escala local entre especies leñosas exóticas y/o nativas dominantes?, y (2 si existe esa segregación, ¿está asociada a variables ambientales? En el 2010 se establecieron 31 parcelas distribuidas en 16 laderas en los bosques Chaqueños de las Sierras de Córdoba, en Argentina central. En cada uno de los sitios de muestreo se relevó la composición y abundancia de todas las especies leñosas con un diámetro a la altura de la base superior a 5cm. Para caracterizar el ambiente en cada una de las parcelas medimos la posición topográfica (pendiente y orientación y algunas propiedades asociadas con la física (densidad aparente y compactación, estructura (profundidad y textura y con la química (pH y el contenido de nutrientes y agua del suelo. A través, de un análisis jerárquico de agrupamiento, se identificaron cinco comunidades de leñosas coexistiendo: (1 Bosques dominados por Ligustrum lucidum, (2 Bosques mixtos dominados por Lithraea molleoides y Celtis australis, (3 Matorrales de Condalia buxifolia, (4 Matorrales de Cotoneaster glaucophyllus, y (5 Pajonales con emergentes de Pyracantha angustifolia. Estas comunidades se asociaron diferencialmente a las variables topográficas y edáficas locales. La segregación ambiental observada sugiere que las especies invasoras tienen una capacidad potencial para colonizar casi todos los ambientes en el área de estudio (variando la

Análise da atividade florestal no município de Viçosa-MG Analysis of forest activity in Viçosa-MG

Directory of Open Access Journals (Sweden)

Alessandro Albino Fontes

2003-08-01

Full Text Available Estudou-se a atividade florestal no município de Viçosa-MG, a partir de questionário aplicado aos agricultores cujas propriedades rurais possuíam florestas plantadas. Foi amostrado um total de 63 propriedades rurais, abrangendo uma área de 2.096,95 ha. As áreas de floresta nativa e plantada, na amostra, foram de 372,00 e 260,17 ha, o que corresponde, respectivamente, a 17,74 e 12,41% da área amostrada. O tipo de floresta nativa predominante foi a capoeira (67,55%, e a espécie preferida para o reflorestamento foi o eucalipto (92,68%. O uso médio da mão-de-obra nas fases de implantação, manutenção e colheita dos plantios florestais foi estimado em 30,21, 13,64 e 61,25 dias-homem/ha, respectivamente, totalizando 105,10 dias-homem/ha, sendo a participação da mão-de-obra familiar de 25,24%. Os custos inerentes à atividade florestal foram estimados em R$419,30/ha para implantação; R$146,49/ha e R$80,34/ha para manutenção no primeiro e segundo ano, respectivamente; e R$2,11/m³ para colheita da madeira. Os plantios florestais concentram-se nas áreas de encostas, e o número médio de empregos gerados pelo reflorestamento (eucalipto foi 0,042 emprego/ha. Concluiu-se, de modo geral, que o reflorestamento é considerado atividade pouco atrativa, não identificando propriedades tipicamente florestais, sendo recomendada a elaboração de políticas públicas de incentivo ao reflorestamento.Forest activity was studied in Viçosa-MG, through a questionnaire applied to farmers who planted forests. A total of 63 farms were sampled, comprising an area of 2,096.95 ha. The natural and planted forest areas sampled were of 372.00 ha and 260.17 ha, corresponding to 17.74% and 12.41%, respectively. The predominant natural forest was the secondary forest (capoeira (67.55%, and the species chosen for reforestation was eucalypt (92.68%. Average labor use in the phases of implementation, maintenance and harvest of the forest plantations was

Adaptation and Validation of the Spanish Version of OSA-18, a Quality of Life Questionnaire for Evaluation of Children with Sleep Apnea-Hypopnea Syndrome.

Science.gov (United States)

Chiner, Eusebi; Landete, Pedro; Sancho-Chust, José Norberto; Martínez-García, Miguel Ángel; Pérez-Ferrer, Patricia; Pastor, Esther; Senent, Cristina; Arlandis, Mar; Navarro, Cristina; Selma, María José

2016-11-01

To analyze the reliability and validity of the Spanish version of the OSA-18 quality of life questionnaire in children with apnea-hypopnea syndrome (SAHS). Children with suspected SAHS were studied with polysomnography (PSG) before and after adenotonsillectomy (AA). Age, gender, clinical data, PSG, anthropometric data, and Mallampati and Brodsky scales were analyzed. OSA-18 was administered at baseline and 3-6months post AA. After translation and backtranslation by bilingual professionals, the internal consistency, reliability, construct validity, concurrent validity, predictive validity and sensitivity to change of the questionnaire was assessed. In total, 45 boys and 15 girls were evaluated, showing BMI 18±4, neck 28±5, Brodsky (0: 7%; 50 to 75%: 6%), AHI 12±7 pre AA. Global Cronbach alpha was 0.91. Correlations between domains were significant except for emotional aspects, although the total scores correlated with all domains (0.50 to 0.90). The factorial analysis was virtually identical to the original structure. The total scores showed good correlation for concurrent validity (0.2-0.45). With regard to predictive validity, the questionnaire adequately differentiated levels of severity according to Mallampati (ANOVA P=.002) and apnea-hypopnea index (ANOVA P=.006). Test-retest reliability was excellent, as was sensitivity to change, both in the total scores (P<.001) and in each domain (P<.001). The Spanish adaptation of the OSA-18 and its psychometric characteristics suggest that the Spanish version is equivalent to the original and can be used in Spanish-speaking countries. Copyright © 2016 SEPAR. Publicado por Elsevier España, S.L.U. All rights reserved.

Impact of second reminder invitation on uptake of screening and cancer detection in BreastCheck.

LENUS (Irish Health Repository)

Fleming, P

2012-01-01

This research aims to quantify the impact of reminder invitations on uptake and cancer detection in Ireland. Examination of BreastCheck\\'s clinical database (2000-2010) to determine number of women screened following first invitation and after reminder; comparison by age group and screening phase with outcomes of recall rate, cancer detection and true positive rates. Of 819,182 first invitations sent 448,974 (54.8%) women attended. 245,157 (66.2%) women attended after reminder invitations, increasing uptake by 29.9% to 694,131 (84.7%) and cancers detected by 1,550 (35%). Women awaiting a reminder were less likely recalled for assessment 9,555 (3.9%) than respondents to first invitation 2,887 (4.04%) (p=0.004). Younger, mainly initial women were more likely recalled for assessment after first invitation. There was no difference between cohorts for cancer detection rate or true positive rate. Reminders increased uptake, supporting international evidence. For programme efficiency attendance at first invitation is optimal. For maximum programme effectiveness attendance must be encouraged with reminders.

Eliciting Information on Sensitive Matters Without Inviting ...

Indian Academy of Sciences (India)

Eliciting Information on Sensitive Matters. Without Inviting Respondents' ... methods based on Randomized Response tech- niques. ... while collecting data on some sensitive issues are well ..... Suppose there is an association of professionals.

Workshop presentations

International Nuclear Information System (INIS)

Sanden, Per-Olof; Edland, Anne; Reiersen, Craig; Mullins, Peter; Ingemarsson, Karl-Fredrik; Bouchard, Andre; Watts, Germaine; Johnstone, John; Hollnagel, Erik; Ramberg, Patric; Reiman, Teemu

2009-01-01

An important part of the workshop was a series of invited presentations. The presentations were intended to both provide the participants with an understanding of various organisational approaches and activities as well as to stimulate the exchange of ideas during the small group discussion sessions. The presentation subjects ranged from current organisational regulations and licensee activities to new organisational research and the benefits of viewing organisations from a different perspective. There were more than a dozen invited presentations. The initial set of presentations gave the participants an overview of the background, structure, and aims of the workshop. This included a short presentation on the results from the regulatory responses to the pre-workshop survey. Representatives from four countries (Sweden, Canada, Finland, and the United Kingdom) expanded upon their survey responses with detailed presentations on both regulatory and licensee safety-related organisational activities in their countries. There were also presentations on new research concerning how to evaluate safety critical organisations and on a resilience engineering perspective to safety critical organisations. Below is the list of the presentations, the slides of which being available in Appendix 2: 1 - Workshop Welcome (Per-Olof Sanden); 2 - CSNI Working Group on Human and Organisational Factors (Craig Reiersen); 3 - Regulatory expectations on justification of suitability of licensee organisational structures, resources and competencies (Anne Edland); 4 - Justifying the suitability of licensee organisational structures, resources and competencies (Karl-Fredrik Ingemarsson); 5 - Nuclear Organisational Suitability in Canada (Andre Bouchard); 6 - Designing and Resourcing for Safety and Effectiveness (Germaine Watts); 7 - Organisational Suitability - What do you need and how do you know that you've got it? (Craig Reiersen); 8 - Suitability of Organisations - UK Regulator's View (Peter

A Mechanically Proved and an Incremental Development of the Session Initiation Protocol INVITE Transaction

Directory of Open Access Journals (Sweden)

Rajaa Filali

2014-01-01

Full Text Available The Session Initiation Protocol (SIP is an application layer signaling protocol used to create, manage, and terminate sessions in an IP based network. SIP is considered as a transactional protocol. There are two main SIP transactions, the INVITE transaction and the non-INVITE transaction. The SIP INVITE transaction specification is described in an informal way in Request for Comments (RFC 3261 and modified in RFC 6026. In this paper we focus on the INVITE transaction of SIP, over reliable and unreliable transport mediums, which is used to initiate a session. In order to ensure the correctness of SIP, the INVITE transaction is modeled and verified using event-B method and its Rodin platform. The Event-B refinement concept allows an incremental development by defining the studied system at different levels of abstraction, and Rodin discharges almost all proof obligations at each level. This interaction between modeling and proving reduces the complexity and helps in assuring that the INVITE transaction SIP specification is correct, unambiguous, and easy to understand.

Equações alométricas para estimativa de carbono em árvores de uma área urbana em Viçosa-MG

Directory of Open Access Journals (Sweden)

Daniel Brianezi

2013-12-01

Full Text Available Objetivou-se com este estudo gerar equações para estimar o carbono presente na arborização do campus-sede da Universidade Federal de Viçosa, contribuindo para o conhecimento sobre a capacidade das áreas verdes urbanas no sequestro e estocagem de carbono. Assim, inventariaram-se todas as árvores com DAP igual ou superior a 5 cm presentes na Universidade. Para as árvores não palmeiras, selecionaram-se 721 árvores-amostra, que foram cubadas rigorosamente em pé através da aplicação sucessiva da expressão de Smalian até o diâmetro-limite de 5 cm, tanto para o fuste quanto para os galhos. No caso das palmeiras, cubaram-se 100% dos indivíduos utilizando a expressão de Huber. A densidade básica da madeira com casca e o teor de carbono foram obtidos, nas palmeiras, com a retirada de um disco na porção do DAP, dada a dificuldade de tradagem. Já nas demais árvores, utilizou-se um trado mecânico. Com base no volume, na densidade básica e no teor de carbono, calcularam-se o carbono total e o carbono dos galhos. Ademais, avaliaram-se os modelos de Schumacher e Hall (1933 e Spurr (1952, modificado para estimar o carbono fixado nesses indivíduos. Nas árvores não palmeiras do campus-sede da Universidade Federal de Viçosa, o carbono total e o carbono dos galhos podem ser estimados, em kg, em razão do Diâmetro à Altura do Peito (DAP, em cm e da Altura Total (Ht, em m, por -0,906586+1,60421*LnDAP+0,37162*LnHt e por -2,052673+1,89903*LnDAP+0,24156*LnHt, respectivamente. Nas palmeiras, o carbono total pode ser estimado por -4,46988+199082*LnDAP+1,06420*LnHt.

A mast fruiting episode of the tropical tree Peltogyne purpurea(Caesalpinaceaein the Osa Peninsula, Costa Rica

Directory of Open Access Journals (Sweden)

Oscar J Rocha

2006-12-01

Full Text Available Se describe un episodio de fructificación en masa en una población de Peltogyne purpurea de la Península de Osa, Costa Rica. En febrero y marzo de 2000, la mayor parte de los árboles de esta especie tuvo una gran cosecha de frutos. En los años anteriores, desde 1995, ninguno o muy pocos árboles produjeron frutos y la producción por árbol fue escasa. La cosecha del año 2000 fue masiva y todos los árboles examinados produjeron frutos abundantes. Este patrón reproductivo podría producir extinciones locales si la extracción maderera no lo toma en cuentaThe existence of mast fruiting has not been well documented in the Neotropics. The occurrence of a mast fruiting episode in the population of the tree Peltogyne purpurea in the Osa Peninsula of Costa Rica is described. In February and March of 2000 most of the trees of this species produced a large fruit crop, compared with 1995-1999, when the number of fruit producing trees was very low or zero and those that did bear fruit, did so at a low intensity. In contrast, the fruit crop of 2000 was massive, all trees examined produced fruits and the intensity of fruiting was maximal. There is not enough information on the event for a hypothesis to be formed because the climatic or biological cues that triggered this sporadic flowering are unknown and there is no meteorological data available for this area. Populations with this mode of reproduction may experience local extinction bacause of logging operations. Rev. Biol. Trop. 54 (4: 1151-1155. Epub 2006 Dec. 15

A mast fruiting episode of the tropical tree Peltogyne purpurea(Caesalpinaceaein the Osa Peninsula, Costa Rica

Directory of Open Access Journals (Sweden)

Oscar J Rocha

2006-12-01

Full Text Available Se describe un episodio de fructificación en masa en una población de Peltogyne purpurea de la Península de Osa, Costa Rica. En febrero y marzo de 2000, la mayor parte de los árboles de esta especie tuvo una gran cosecha de frutos. En los años anteriores, desde 1995, ninguno o muy pocos árboles produjeron frutos y la producción por árbol fue escasa. La cosecha del año 2000 fue masiva y todos los árboles examinados produjeron frutos abundantes. Este patrón reproductivo podría producir extinciones locales si la extracción maderera no lo toma en cuenta

48 CFR 14.203-2 - Dissemination of information concerning invitations for bids.

Science.gov (United States)

2010-10-01

... 14.203-2 Dissemination of information concerning invitations for bids. Procedures concerning display... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Dissemination of information concerning invitations for bids. 14.203-2 Section 14.203-2 Federal Acquisition Regulations System...

Do invitations for cervical screening provide sufficient information to enable informed choice?

DEFF Research Database (Denmark)

Kolthoff, Sie Karen; Hestbech, Mie Sara; Jørgensen, Karsten Juhl

2016-01-01

or unmentioned. The same applied to other important harms, such as false-positive results and the psychological consequences from an abnormal test result. The majority of invitations took a paternalistic approach. While only two invitations (17%) included a pre-assigned appointment date, eight (70...

An Invitation to Mathematics

CERN Document Server

Schleicher, Dierk

2011-01-01

This "Invitation to Mathematics" consists of 14 contributions, many from the world's leading mathematicians, which introduce the readers to exciting aspects of current mathematical research. The contributions are as varied as the personalities of active mathematicians, but together they show mathematics as a rich and lively field of research. The contributions are written for interested students at the age of transition between high school and university who know high school mathematics and perhaps competition mathematics and who want to find out what current research mathematics is

COUNTER-INTERVENTION, INVITATION, BOTH, OR NEITHER ?

African Journals Online (AJOL)

eliasn

2 See Testimony by David H. Shinn, Somalia: U.S. Govrenemnt Policy and Challenges, ... a state of relative peace—one that can be best described as cold peace. ... denied sending its troops to Somalia until it formally declared war on 24 ...... Lebanese government, the invitation of the USSR by the dubious government of.

Book Presentation | 27 February

CERN Multimedia

The CERN Library

2013-01-01

"A caccia del bosone di Higgs. Magneti, governi, scienziati e particelle nell'impresa scientifica del secolo" by Luciano Maiani and Romeo Bassoli, published by Mondadori. On Wednesday 27 February Luciano Maiani will present the book "A caccia del bosone di Higgs. Magneti, governi, scienziati e particelle nell'impresa scientifica del secolo". More information here. The presentation will take place in the Council Chamber at 16.00 and will be followed by a debate and book signing. The book will be on sale. You are cordially invited.

L'invisible invité

OpenAIRE

Frémy, Anne

2012-01-01

Tiré du site Internet de Onestar Press: ""They’re a kind of cabin or hut, very basic and awkwardly assembled, wedged into the space of the balcony between the guardrail and the wall of the building.The vertical sides are made of plywood, canvas or tarp, and are topped by a vegetal roofing that is more or less dry, more or less green, threaded with palm wattle. These huts are opaque and seem to communicate with apartments…" Excerpt from L’Invisible invité by Anne Frémy, english by Bruce Bender...

Invitations received from potential predatory publishers and fraudulent conferences: a 12-month early-career researcher experience.

Science.gov (United States)

Mercier, Eric; Tardif, Pier-Alexandre; Moore, Lynne; Le Sage, Natalie; Cameron, Peter A

2018-02-01

This study aims to describe all unsolicited electronic invitations received from potential predatory publishers or fraudulent conferences over a 12-month period following the first publication as a corresponding author of a junior academician. Unsolicited invitations received at an institutional email address and perceived to be sent by predatory publishers or fraudulent conferences were collected. A total of 502 invitations were included of which 177 (35.3%) had subject matter relevant to the recipient's research interests and previous work. Two hundred and thirty-seven were invitations to publish a manuscript. Few disclosed the publication fees (32, 13.5%) but they frequently reported accepting all types of manuscripts (167, 70.5%) or emphasised on a deadline to submit (165, 69.6%). Invitations came from 39 publishers (range 1 to 87 invitations per publisher). Two hundred and ten invitations from a potential fraudulent conference were received. These meetings were held in Europe (97, 46.2%), North America (65, 31.0%), Asia (20.4%) or other continents (5, 2.4%) and came from 18 meeting organisation groups (range 1 to 137 invitations per organisation). Becoming an editorial board member (30), the editor-in-chief (1), a guest editor for journal special issue (6) and write a book chapter (11) were some of the roles offered in the other invitations included while no invitation to review a manuscript was received. Young researchers are commonly exposed to predatory publishers and fraudulent conferences following a single publication as a corresponding author. Academic institutions worldwide need to educate and inform young researchers of this emerging problem. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Nuclear Structure: Dubna Symposium 1968. Invited Papers from the International Symposium on Nuclear Structure

International Nuclear Information System (INIS)

1968-01-01

Invited papers of a Symposium organized by the Joint Institute for Nuclear Research, Dubna, supported by IUPAP and IAEA, and held in Dubna from 4 to 11 July 1968. The meeting was attended by about 450 scientists from 30 countries. The volume contains the invited papers, all by distinguished scientists, and the discussions and short contributions that followed the presentation of these papers. Contents: I. Nuclear structure at low excitations (15 papers) ; II. Nuclear structure at high excitations (6 papers): III. Open problems in nuclear physics (3 papers); IV. Equilibrium deformations (6 papers); V. General properties of nuclei (6 papers); VI. Closing remarks; List of contributions; List of seminar papers; List of participants; Author index. All papers, discussions and short contributions are in English; the abstracts are in English and Russian, which were the working languages of the Symposium. (author)

Receptivity to sexual invitations from strangers of the opposite gender

DEFF Research Database (Denmark)

Hald, Gert Martin; Hogh-Olesen, Henrik

2010-01-01

This study investigated the primary conclusion from Clark and Hatfield's often cited field experiment ``Consent to Sex with a Stranger'' that men agree to sexual invitations from moderately attractive strangers of the opposite gender more readily than women do. In addition, this study investigated...... whether rates of consent are influenced by a subject's age, relationship status, rating of confederate attractiveness, and type of sexual invitation. A number of moderately attractive confederates of the opposite gender individually approached 173 men and 216 women. After a standard introduction...

Inviting parents to take part in paediatric palliative care research: A mixed-methods examination of selection bias

OpenAIRE

Crocker, Joanna C; Beecham, Emma; Kelly, Paula; Dinsdale, Andrew P; Hemsley, June; Jones, Louise; Bluebond-Langner, Myra

2015-01-01

Background: Recruitment to paediatric palliative care research is challenging, with high rates of non-invitation of eligible families by clinicians. The impact on sample characteristics is unknown. Aim: To investigate, using mixed methods, non-invitation of eligible families and ensuing selection bias in an interview study about parents? experiences of advance care planning (ACP). Design: We examined differences between eligible families invited and not invited to participate by clinicians us...

Inviting parents to take part in paediatric palliative care research: a mixed-methods examination of selection bias.

Science.gov (United States)

Crocker, Joanna C; Beecham, Emma; Kelly, Paula; Dinsdale, Andrew P; Hemsley, June; Jones, Louise; Bluebond-Langner, Myra

2015-03-01

Recruitment to paediatric palliative care research is challenging, with high rates of non-invitation of eligible families by clinicians. The impact on sample characteristics is unknown. To investigate, using mixed methods, non-invitation of eligible families and ensuing selection bias in an interview study about parents' experiences of advance care planning (ACP). We examined differences between eligible families invited and not invited to participate by clinicians using (1) field notes of discussions with clinicians during the invitation phase and (2) anonymised information from the service's clinical database. Families were eligible for the ACP study if their child was receiving care from a UK-based tertiary palliative care service (Group A; N = 519) or had died 6-10 months previously having received care from the service (Group B; N = 73). Rates of non-invitation to the ACP study were high. A total of 28 (5.4%) Group A families and 21 (28.8%) Group B families (p research findings. Non-invitation and selection bias should be considered, assessed and reported in palliative care studies. © The Author(s) 2014.

Papilionoideae (Leguminosae arbóreas e lianas na estação de pesquisa, treinamento e educação ambiental (EPTEA, Mata do Paraíso, Viçosa, Zona da Mata Mineira Trees and lianes of the papilionoideae (Leguminosae in the research, training and environmental education station (EPTEA, Mata do Paraíso, Viçosa, Zona da Mata Mineira

Directory of Open Access Journals (Sweden)

Izabella Martins da Costa Rodrigues

2007-01-01

Full Text Available Este trabalho consiste em um levantamento florístico das árvores e lianas pertencentes à Papilionoideae da Mata do Paraíso, importante fragmento de Floresta Estacional Semidecidual Submontana, no Município de Viçosa, Zona da Mata mineira. A pesquisa de campo foi realizada por meio de visitas à área de estudo, no período de julho/2004 a agosto/2005. Foram reconhecidos 12 táxons infra-específicos pertencentes a oito gêneros, sendo Machaerium Pers. (4 spp. e Dalbergia L. f. (2 spp. os mais representativos. São apresentados chaves de identificação, descrições, ilustrações e comentários sobre os táxons analisados. Dalbergia nigra (Vell. Allemão ex Benth., espécie vulnerável, e Ormosia vicosana Rudd, endêmica da região, foram encontradas na EPTEA.This work is a floristic survey of trees and lianas of the Papilionoideae in the Mata do Paraíso, an important fragment of Submontane Semideciduous Seasonal Forest, in Viçosa, Zona da Mata Mineira. The fieldwork was carried out through visits to the studied area, from July/2004 to August/2005. Twelve taxa represented by eight genera were recorded. Machaerium Pers. (4spp. and Dalbergia L. f. (2 spp. were the most representatives. Identification keys, descriptions and illustrations are presented for the analyzed taxa. Dalbergia nigra (Vell. Allemão ex Benth., vulnerable species and, Ormosia vicosana Rudd, endemic for the region were found at EPTEA.

Enabling narrative pedagogy: inviting, waiting, and letting be.

Science.gov (United States)

Ironside, Pamela M

2014-01-01

This article describes how teachers enable Narrative Pedagogy in their courses by explicating the Concernful Practice Inviting: Waiting and Letting Be. Narrative Pedagogy, a research-based, phenomenological approach to teaching and learning, extends conventional pedagogies and offers nursing faculty an alternative way of transforming their schools and courses. Using hermeneutic phenomenology, interview data collected over a 10-year period were analyzed by coding practical examples of teachers' efforts to enact Narrative Pedagogy. When Narrative Pedagogy is enacted, teachers and students focus on thinking and learning together about nursing phenomena and seek new understandings about how they may provide care in the myriad situations they encounter. Although the Concernful Practices co-occur, explicating inviting experiences can assist new teachers, and those seeking to extend their pedagogical literacy, by providing new understandings of how Narrative Pedagogy can be enacted.

Flora de importância polinífera para Apis mellifera (L. na região de Viçosa, MG

Directory of Open Access Journals (Sweden)

Anna Frida Hatsue Modro

2011-10-01

Full Text Available Procurou-se conhecer a flora de importância polinífera para Apis mellifera (L. na região de Viçosa, MG, em período de entressafra de mel, entre agosto e dezembro de 2005. O experimento foi realizado em dois apiários distintos, cada um com cinco colmeias. As cargas retidas nos coletores de pólen instalados nas colmeias foram analisadas quanto à origem botânica. As plantas em floração no entorno dos apiários foram coletadas e identificadas. A maioria das plantas de importância polinífera para abelhas na região de Viçosa era nativa, localizada em jardins e com hábito arbóreo. Pela análise palinológica, verificou-se que espécies como Anadenanthera colubrina, Arecaceae sp., Baccharis dracunculifolia, B. melastomaefolia, Coffea spp., Emilia sagittata, Eugenia uniflora, Mikania cordifolia, M. hirsutissima, Myrcia fallax, Psidium guajava, Vernonia condensata, V. diffusa, V. lanuginosa e V. mariana são potenciais recursos poliníferos a serem utilizados no período de entressafra do mel. Os resultados indicaram a importância de plantas localizadas em áreas abertas para o forrageamento de pólen por A. mellifera e confirmaram o potencial polinífero da região estudada, durante o período de entressafra do mel.

Adoção sequencial de tecnologia pós-colheita aplicada à cafeicultura em Viçosa (MG

Directory of Open Access Journals (Sweden)

Matheus Wemerson Gomes Pereira

2010-06-01

Full Text Available O processo de adoção tecnológica na agricultura é de fundamental importância para o aumento da produtividade e a melhoria da qualidade dos produtos agrícolas. O objetivo deste artigo é avaliar os determinantes da adoção da tecnologia pós-colheita na cafeicultura em Viçosa (MG, no ano de 2007. Os resultados sugerem que o modelo sequencial é o mais apropriado à análise e que as variáveis associativismo, rentabilidade, treinamento, crédito, capital próprio e escolaridade são os principais determinantes na adoção de estágios mais elevados de tecnologia pós-colheita aplicada à cafeicultura. Os efeitos marginais mais importantes para adoção de maiores níveis tecnológicos são associativismo, treinamento, crédito e rentabilidade.The process of tecnology adoption in agriculture is fundamentally important for increasing productivity and improving the quality of agricultural products. The objective of this study is to evaluate the factors that determine the technological adoption of post-harvest coffee employed in Viçosa (MG in the year of 2007. The results indicate that the sequential model is more appropriate for the analysis and the most important determinants for the adoption of higher levels of post-harvest technology are association, profitability, training, education, credit, stock of capital, and years at school. The most important marginal effects for the adoption of higher levels of post-harvest technology are association, training, credit and profitability.

14 CFR 11.85 - Does FAA invite public comment on petitions for exemption?

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Does FAA invite public comment on petitions... Rulemaking and for Exemption § 11.85 Does FAA invite public comment on petitions for exemption? Yes, FAA... the reasons for requesting it; and (e) A request for comments to assist FAA in evaluating the petition. ...

Determinants of Unintentional Leaks During CPAP Treatment in OSA.

Science.gov (United States)

Lebret, Marius; Arnol, Nathalie; Martinot, Jean-Benoît; Lambert, Loïc; Tamisier, Renaud; Pepin, Jean-Louis; Borel, Jean-Christian

2018-04-01

Unintentional leakage from the mouth or around the mask may lead to cessation of CPAP treatment; however, the causes of unintentional leaks are poorly understood. The objectives of this study were (1) to identify determining factors of unintentional leakage and (2) to determine the effect of the type of mask (nasal/oronasal) used on unintentional leakage. Seventy-four polysomnograms from patients with OSA syndrome treated with auto-CPAP were analyzed (23 women; 56 ± 13 years; BMI, 32.9 kg/m 2 (range, 29.0-38.0 kg/m 2 ). Polysomnographic recordings were obtained under auto-CPAP, and mandibular behavior was measured with a magnetic sensor. After sleep and respiratory scoring, polysomnographic signals were computed as mean values over nonoverlapping 10-s intervals. The presence/absence of unintentional leakage was dichotomized for each 10-s interval (yes/no). Univariate and multivariate conditional regression models estimated the risk of unintentional leaks during an interval "T" based on the explanatory variables from the previous interval "T-1." A sensitivity analysis for the type of mask was then conducted. The univariate analysis showed that mandibular lowering (mouth opening), a high level of CPAP, body position (other than supine), and rapid eye movement (REM) sleep increased the risk of unintentional leaks and microarousal decreased it. In the multivariate analysis, the same variables remained independently associated with an increased risk of unintentional leakage. The sensitivity analysis showed that oronasal masks reduced the risk of unintentional leaks in cases of mouth opening and REM sleep. Mouth opening, CPAP level, sleep position, and REM sleep independently contribute to unintentional leakage. These results provide a strong rationale for the definition of phenotypes and the individual management of leaks during CPAP treatment. Copyright © 2017 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.

Epidemiological analysis of structural alterations of the nasal cavity associated with obstructive sleep apnea syndrome (OSA).

Science.gov (United States)

Mekhitarian Neto, Levon; Fava, Antonio Sérgio; Lopes, Hugo Canhete; Stamm, Aldo

2005-01-01

The objective of this paper is to demonstrate that structural alterations of the nasal cavity, e.g. septal deviation and conchal hypertrophy have high incidence in patients with sleep apnea and hypopnea syndrome and must be addressed with associated specific procedures of the syndrome. Clinical retrospective. A retrospective study of 200 patients was performed, with 196 male and 4 female, attended at the otorhinolaryngology ambulatory of Hospital Prof. Edmundo Vasconcelos and Unidade Paulista de Otorrinolaringologia, all of them subjected to polysomnography, otorhinolaryngological physical exam, endoscopy exam, and surgical treatment with nasal and pharyngeal procedures. All of them were subjected to pharyngeal procedure: uvulopalatopharyngoplasty or uvulopalatoplasty and nose procedure: 176 septoplasty with partial turbinectomy (88%) and 24 isolated turbinectomy, with satisfactory results. We can see that structural alterations of the nasal cavity have high incidence in patients with OSA.

Estaquillas leñosas de fácil enraizamiento: Estudio del Esclerenquima Estaquillas leñosas de fácil enraizamiento: Estudio del Esclerénquima

Directory of Open Access Journals (Sweden)

González Elena

1986-12-01

Full Text Available An anatomy study was made of following wood easy-to-root species: Aucuba japonica Thunb., Buddleja  japonica Hemsley,  Buxus sempervirens L., Citrus aurantium.  L., Citrus limon (L. Burm. fil.,  Cvdonia oblonga Miller,  Erica arborea L., Escallonia rubra (Ruiz & Pavón Pers., Euonymus japonicus L. fil., Forsythia viridissima Lindl., Hydrangea macrophylla Ser., Morus alba L., Populus nigra L.,  Rhododendron ponticum L., Salix atrocinerea Brot., Salix  viminalis L., Sambucus nigra L. and Symphoricarpos albus (L. S. F. Blake.  It was observed the presence or absence of a discontinous sclerenchyma ring so the species studied had not a mechanical barrier to the emergence of adventitious roots. Se realizó un estudio histológico de las siguientes especies leñosas de fácil enraizamiento: Aucuba japonica Thumb, Buddleja japonica Hemsley, Buxus sempervirens L., Citrus aurantium L., Citrus limon (L. Burm, fil., Cydonia oblonga Miller, Erica arborea L., Escallonia rubra (Ruiz & Pavón Pers., Euonymus japonicus L. fil., Forsythia viridissima Lindl., Hydrangea macrophylla Ser., Morus alba L. Populus nigra L., Rhododendron ponticum L., Salix atrocinerea Brot., Salix viminalis L., Sambucus nigra L. y Syrnphoricarpos albus (L. S. F. Blake. Se observó la presencia o ausencia de un anillo discontinuo de esclerénquima, por lo tanto dichas especies no poseen ningún impedimento mecánico para la emergencia de las raíces adventicias.

Inviting In the Private Sector

Science.gov (United States)

2002-10-01

private sector . After all, corruption does not just involve government. Business people and lawyers and citizens pay the bribes, even as they condemn bribery. They should be invited to become part of the solution. But how? The first point to note is that business people and citizens know where corruption exists and how corrupt systems work. Citizens understand how bribery shapes the services they receive or don’t receive. Accountants know the illicit games played with audits and taxes. Lawyers understand corrupt legal practices. Business people know all about corrupt

Environmental service payments: evaluating biodiversity conservation trade-offs and cost-efficiency in the Osa Conservation Area, Costa Rica.

Science.gov (United States)

Barton, D N; Faith, D P; Rusch, G M; Acevedo, H; Paniagua, L; Castro, M

2009-02-01

The cost-efficiency of payments for environmental services (PES) to private landowners in the Osa Conservation Area, Costa Rica, is evaluated in terms of the trade-off between biodiversity representation and opportunity costs of conservation to agricultural and forestry land-use. Using available GIS data and an 'off-the-shelf' software application called TARGET, we find that the PES allocation criteria applied by authorities in 2002-2003 were more than twice as cost-efficient as criteria applied during 1999-2001. Results show that a policy relevant assessment of the cost-effectiveness of PES relative to other conservation policies can be carried out at regional level using available studies and GIS data. However, there are a number of data and conceptual limitations to using heuristic optimisation algorithms in the analysis of the cost-efficiency of PES. Site specific data on probabilities of land-use change, and a detailed specification of opportunity costs of farm land, labour and capital are required to use algorithms such as TARGET for ranking individual sites based on cost-efficiency. Despite its conceptual soundness for regional conservation analysis, biodiversity complementarity presents a practical challenge as a criterion for PES eligibility at farm level because it varies depending on the set of areas under PES contracts at any one time.

The predictive value of drug-induced sleep endoscopy for CPAP titration in OSA patients.

Science.gov (United States)

Lan, Ming-Chin; Hsu, Yen-Bin; Lan, Ming-Ying; Huang, Yun-Chen; Kao, Ming-Chang; Huang, Tung-Tsun; Chiu, Tsan-Jen; Yang, Mei-Chen

2017-12-15

The aim of this study was to identify possible upper airway obstructions causing a higher continuous positive airway pressure (CPAP) titration level, utilizing drug-induced sleep endoscopy (DISE). A total of 76 patients with obstructive sleep apnea (OSA) underwent CPAP titration and DISE. DISE findings were recorded using the VOTE classification system. Polysomnographic (PSG) data, anthropometric variables, and patterns of airway collapse during DISE were analyzed with CPAP titration levels. A significant association was found between the CPAP titration level and BMI, oxygen desaturation index (ODI), apnea-hypopnea index (AHI), and neck circumference (NC) (P CPAP titration level (P CPAP titration level and any other collapse at the tongue base or epiglottis. By analyzing PSG data, anthropometric variables, and DISE results with CPAP titration levels, we can better understand possible mechanisms resulting in a higher CPAP titration level. We believe that the role of DISE can be expanded as a tool to identify the possible anatomical structures that may be corrected by oral appliance therapy or surgical intervention to improve CPAP compliance.

Estado nutricional e fatores associados em idosos do Município de Viçosa, Minas Gerais, Brasil Nutritional status and associated factors among the elderly in Viçosa, Minas Gerais State, Brazil

Directory of Open Access Journals (Sweden)

Clarissa de Matos Nascimento

2011-12-01

Full Text Available Investigaram-se as prevalências de baixo peso e excesso de peso, bem como os fatores associados em idosos. Trata-se de um estudo transversal, com 621 idosos residentes no Município de Viçosa, Minas Gerais, Brasil, realizado em 2009. As informações foram obtidas por meio de entrevistas domiciliares e se referiam à avaliação do estado nutricional, condições sociodemográficas e de saúde. Do total de pessoas estudadas, 53,3% eram do gênero feminino. A mediana do IMC foi de 26,40kg/m² (mínima 15,20 e máxima 46,82 e foi menor para os homens do que para as mulheres. A prevalência de excesso de peso foi elevada (45%; IC95%: 40%-49%, diminuiu com a idade, associou-se positivamente ao gênero feminino e história de artrite/artrose, e negativamente à faixa etária de 80 anos ou mais e ao tabagismo. A prevalência de baixo peso foi maior no gênero masculino (18,2%, aumentou com o avanço da idade e associou-se positivamente à pior percepção de saúde. O conjunto dos resultados salientam a importância de estratégias em saúde que favoreçam mudanças no estilo de vida e hábitos alimentares saudáveis.This cross-sectional study in 2009 focused on the prevalence of underweight and overweight and associated factors in a sample of 621 elderly individuals in Viçosa, Minas Gerais State, Brazil. Data were obtained through home interviews on nutritional status and socio-demographic and health conditions. Of the total sample, 53.3% were females. Median BMI was 26.40kg/m² (range = 15.20-46.82 and was lower for men than for women. Prevalence of overweight was high (45%; 95%CI: 40%-49%, decreased with age, was positively associated with female gender and history of arthritis/arthrosis, and was negatively associated with age 80 years or older and smoking. Prevalence of underweight was high in men (18.2%, increased with age, and was positively associated with worse self-rated health. The findings highlight the importance of health strategies

Anemia ferropriva em crianças de 6 a 12 meses atendidas na rede pública de saúde do município de Viçosa, Minas Gerais Iron deficiency anemia in 6 to 12-month-old infants attended at the public health service of Viçosa, Minas Gerais, Brazil

Directory of Open Access Journals (Sweden)

Danielle Góes da SILVA

2002-09-01

Full Text Available Este estudo teve como objetivos verificar a prevalência de anemia em lactentes de 6 a 12 meses atendidos na rede pública de saúde do município de Viçosa, MG e analisar alguns possíveis fatores de risco. As informações foram obtidas através de questionário aplicado aos responsáveis pela criança e através da verificação de medidas antropométricas e da dosagem de hemoglobina por hemoglobinômetro portátil. No diagnóstico de anemia, utilizou-se o ponto de corte de 11 g/dL. A prevalência de anemia ferropriva nas 204 crianças estudadas foi 60,8%, e 55,6% dos casos de anemia eram graves. A média da hemoglobina foi 9,28±1,07 nos anêmicos e 12,07±0,89 mg/dL nos não-anêmicos. A baixa escolaridade paterna e a idade materna mostraram associação estatística com a anemia (pThis study aimed at verifying the prevalence of anemia in 6 to 12-month-old infantsattended at the public health service of the city of Viçosa, state of Minas Gerais, and analyzing some possible risk factors. Information was obtained through questionnaire applied to those responsible for the infants and through the verification of the anthropometric measures and the hemoglobin dosage by portable hemoglobinometer. In diagnosing anemia, a 11g/dL cutoff point was used. The prevalence of iron deficiency anemia in a total of 204 infants reached 60.8%, and 55.6% of the cases of anemia were serious. The hemoglobin average was 9.28±1.07 mg/dL in anemic infants, and 12.07± 0.89 mg/dL in non-anemic ones. The father's low school level and the mother's age showed statistical association with anemia (p<0.05. A high prevalence and severity of the anemia was found, emphasizing the need for prevention and control of this disease in the city of Viçosa.

Differences in diagnostic activity in general practice and findings for individuals invited to the danish screening programme for colorectal cancer: a population-based cohort study.

Science.gov (United States)

Juul, Jakob Søgaard; Andersen, Berit; Laurberg, Søren; Carlsen, Anders Helles; Olesen, Frede; Vedsted, Peter

2018-06-22

To investigate the diagnostic activity in general practice and the cumulative incidence of colorectal cancer (CRC) in individuals invited to the Danish national screening programme for CRC. A historical population-based cohort study. The Danish CRC screening programme and general practice. The 376,198 individuals invited to the Danish CRC screening programme from 1 March to 31 December 2014. The diagnostic activity (consultations and haemoglobin measures) in general practice in the year preceding the screening invitation and the cumulated incidence of CRC in the year following the screening invitation. Screening participants had significantly higher diagnostic activity than non-participants. Individuals with a positive faecal immunochemical test (FIT) had higher diagnostic activity compared to individuals with a negative FIT, and a small increase in the months leading up to the invitation. Individuals with a screen-detected CRC had lower diagnostic activity than individuals with no CRC. In total, 308 (25.3%) of CRCs diagnosed in the invited population were diagnosed outside the screening programme. Non-participants with CRC more often had low socio-economic status, high comorbidity and stage IV CRC than participants with CRC. There was a tendency that participants and those with a positive FIT had a higher diagnostic activity the year before the screening. This was not seen for those with CRC detected through screening. CRC must still be diagnosed in general practice in the invited population and non-participants are of special interest as they have higher risk of late stage CRC. Key Points Current awareness:Individuals with colorectal cancer (CRC) in screening may be symptomatic and CRC may still occur outside screening in the invited population. Most important points:The majority of individuals with CRC in screening cannot be expected to be diagnosed on symptomatic presentation in general practice GPs have to be aware that CRC still occurs outside screening in

Carotene and provitamin A content of vegetables sold in Viçosa, MG, Brazil, during spring and winter

Directory of Open Access Journals (Sweden)

Pollyanna Costa Cardoso

2009-09-01

Full Text Available This study investigated the α- and β-carotene content and provitamin A value of four leafy vegetables sold at local and street markets in Viçosa, MG, Brazil, in the spring and winter of 2002. Carotenoids were analyzed by high-performance liquid chromatography. α-Carotene was detected in all samples sold during spring, but was only present in a few samples of smooth and curly lettuce and kale in winter. β-Carotene was found in marked quantities in all leafy vegetables analyzed. Duncan's test (α = 5% showed significantly higher α-carotene content in curly lettuce and vitamin A value in large-leaved watercress in the spring. Mean β-carotene content and vitamin A value were 7544, 8751, 2584, 2792, 8193, and 5338 μg/100 g and 666, 760, 227, 238, 698, and 460 μg RAE/100 g in large-leaved and hydroponic watercress, smooth and curly lettuce, kale and spinach, respectively. All leafy vegetables analyzed represent important sources of provitamin A and supply an important part of the daily requirements of children and adults.Investigou-se o conteúdo de α e β-caroteno e avaliou-se o valor pro-vitamínico A de quatro hortaliças folhosas comercializadas em mercados locais e feira- livre de Viçosa, MG durante a primavera e o inverno de 2002. Os carotenóides foram analisados por Cromatografia Líquida de Alta Eficiência (CLAE. O α-caroteno foi detectado em todas as amostras analisadas na primavera, porém no inverno, somente algumas amostras de alface crespa e lisa, e couve apresentaram tal carotenóide. O β-caroteno foi encontrado, em quantidades apreciáveis, em todas as hortaliças folhosas analisadas. O teste de Duncan (α=5% detectou que o conteúdo de α-caroteno em alface crespa e o valor de vitamina A em agrião de folha larga foram estatisticamente superiores na primavera. Os teores médios de β-caroteno e de valor de vitamina A para agrião de folha larga e hidropônico, alface crespa e lisa, couve e espinafre foram: 7544; 8751

Invitation Choice Structure Has No Impact on Attendance in a Female Business Training Program in Kenya

Science.gov (United States)

Diwan, Faizan; Makana, Grace; McKenzie, David; Paruzzolo, Silvia

2014-01-01

Business training programs are a common form of support to small businesses, but organizations providing this training often struggle to get business owners to attend. We evaluate the role of invitation choice structure in determining agreement to participate and actual attendance. A field experiment randomly assigned female small business owners in Kenya (N = 1172) to one of three invitation types: a standard opt-in invitation; an active choice invitation where business owners had to explicitly say yes or no to the invitation; and an enhanced active choice invitation which highlighted the costs of saying no. We find no statistically significant effect of these alternative choice structures on willingness to participate in training, attending at least one day, and completing the course. The 95 percent confidence interval for the active treatment effect on attendance is [−1.9%, +9.5%], while for the enhanced active choice treatment it is [−4.1%, +7.7%]. The effect sizes consistent with our data are smaller than impacts measured in health and retirement savings studies in the United States. We examine several potential explanations for the lack of effect in a developing country setting. We find evidence consistent with two potential reasons being limited decision-making power amongst some women, and lower levels of cognition making the enhanced active choice wording less effective. PMID:25299647

Invitation choice structure has no impact on attendance in a female business training program in Kenya.

Science.gov (United States)

Diwan, Faizan; Makana, Grace; McKenzie, David; Paruzzolo, Silvia

2014-01-01

Business training programs are a common form of support to small businesses, but organizations providing this training often struggle to get business owners to attend. We evaluate the role of invitation choice structure in determining agreement to participate and actual attendance. A field experiment randomly assigned female small business owners in Kenya (N = 1172) to one of three invitation types: a standard opt-in invitation; an active choice invitation where business owners had to explicitly say yes or no to the invitation; and an enhanced active choice invitation which highlighted the costs of saying no. We find no statistically significant effect of these alternative choice structures on willingness to participate in training, attending at least one day, and completing the course. The 95 percent confidence interval for the active treatment effect on attendance is [-1.9%, +9.5%], while for the enhanced active choice treatment it is [-4.1%, +7.7%]. The effect sizes consistent with our data are smaller than impacts measured in health and retirement savings studies in the United States. We examine several potential explanations for the lack of effect in a developing country setting. We find evidence consistent with two potential reasons being limited decision-making power amongst some women, and lower levels of cognition making the enhanced active choice wording less effective.

By invitation only

CERN Multimedia

Antonella Del Rosso

2011-01-01

The Hôtel Métropole in Brussels is a legendary conference venue that will ring a bell to all physicists. 100 years after the first meeting of the Conseil de Physique Solvay, a representative group of the world’s most eminent physicists met again in October this year in the Excelsior Room to discuss “The Theory of the Quantum World”. Three members of CERN's Theory Group were invited to participate. Gian Giudice, one of them, shares with us his thoughts and impressions about this exclusive conference.   Attendees at the 25th Solvay Conference on Physics, Brussels. Photo provided by "International Solvay Institutes". “In the tradition of the Solvay Conferences, this is a discussion-oriented meeting with few talks by rapporteurs.” Thus reads the Introduction to the Scientific Programme of the Solvay Conference on Physics. In the Conference programme, the rapporteurs speak for only 30 minutes,...

Sleep architecture in school-aged children with primary snoring.

Science.gov (United States)

Zhu, Yin; Au, Chun-Ting; Lam, Hugh S; Chan, Ching-Ching K; Ho, Crover; Wing, Yun-Kwok; Li, Albert M

2014-03-01

We aimed to examine if sleep architecture was altered in school-aged children with primary snoring (PS). Children ages 6 to 13 years from 13 primary schools were randomly recruited. A validated obstructive sleep apnea (OSA) screening questionnaire was completed by their parents. Children at high risk for OSA and a randomly chosen low-risk group were invited to undergo overnight polysomnography (PSG) and clinical examination. Participants were classified into healthy controls, PS, mild OSA, and moderate to severe OSA (MS OSA) groups for comparison. A total of 619 participants underwent PSG (mean age, 10.0 ± 1.8 years; 396 (64.0%) boys; 524 (84.7%) prepubertal). For the cohort as a whole, there were no significant differences in measures of sleep architecture between PS and nonsnoring healthy controls. In the multiple regression model, percentage of nonrapid eye movement (NREM) stage 1 (N1) sleep had a significantly positive association, whereas percentage of slow-wave sleep (SWS) had a significantly negative association with sleep-disordered breathing (SDB) severity after controlling for age, gender, body mass index (BMI) z score, and pubertal status. In prepubertal children with PS, no significant disruption of sleep architecture was found. However, pubertal adolescent PS participants had significantly higher adjusted percentage of N1 sleep and wake after sleep onset (WASO) compared to healthy controls. PS did not exert significant adverse influences on normal sleep architecture in prepubertal school-aged children. Nevertheless, pubertal adolescents with PS had increased N1 sleep and WASO. Copyright © 2013 Elsevier B.V. All rights reserved.

76 FR 53693 - Notice of Invitation To Participate; Coal Exploration License Application COC-74911, Colorado

Science.gov (United States)

2011-08-29

...] Notice of Invitation To Participate; Coal Exploration License Application COC-74911, Colorado AGENCY: Bureau of Land Management, Interior. ACTION: Notice. SUMMARY: Pursuant to the Mineral Leasing Act of 1920... America in lands located in Delta County, Colorado. DATES: This notice of invitation was published in the...

Contaminación fecal en varios ríos de la Gran Área Metropolitana y la Península de Osa Fecal contamination in several rivers of the Greater Metropolitan Area and the Osa Peninsula

Directory of Open Access Journals (Sweden)

Guillermo Calvo Brenes

2012-12-01

Full Text Available La contaminación en los ríos de Costa Rica es un problema que merece especial atención. El concepto “contaminación del agua” implica la incorporación de materias extrañas a esta, tales como microorganis- mos (coliformes totales y fecales, productos quími- cos (jabones, fer tilizantes, pesticidas, metales pesados (cromo, plomo, mercurio, etc. o materia orgánica proveniente de los suelos a través de la escorrentía superficial y de las aguas residuales domésticas. Estas materias deterioran la calidad del agua y reducen los diferentes usos que podría tener un río. El recurso hídrico es importante tanto para la preservación de la vida humana como para la conservación de la flora y fauna. Costa Rica se ha caracterizado por ser un país poseedor de una rica biodiversidad. Sin embargo, muchos de los ríos de la Gran Área Metropolitana ya presentan una contaminación severa, según el Índice holandés de clasificación de la calidad del agua. En este estudio se analizó el contenido de colifor- mes fecales en 10 ríos de las provincias de San José, Alajuela, Heredia y Car tago, así como de la Península de Osa. Para correlacionar el contenido de colifor- mes fecales con la densidad poblacional, además, se muestrearon tres puntos en cada río: la zona alta cercana a la naciente, la zona media y la zona baja cercana a su desembocadura. Se encontró que los puntos de muestreo con densi- dades poblacionales medias o altas están altamente contaminados con coliformes fecales.Varios de ellos superan el límite máximo permisible en el contenido de coliformes fecales establecido por los reglamen- tos nacionales para el uso de los ríos en actividades de recreación de contacto primario. También se determinó que las zonas con menor pobla- ción, tales como los ríos Tigre y Rincón en la Península de Osa, el río Poás en Alajuela en todo su recorrido y los ríos Purires y Birrís en Cartago, en sus zonas medias y altas, están menos

Effects of CPAP-therapy on brain electrical activity in obstructive sleep apneic patients: a combined EEG study using LORETA and Omega complexity : reversible alterations of brain activity in OSAS.

Science.gov (United States)

Toth, Marton; Faludi, Bela; Kondakor, Istvan

2012-10-01

Effects of initiation of continuous positive airway pressure (CPAP) therapy on EEG background activity were investigated in patients with obstructive sleep apnea syndrome (OSAS, N = 25) to test possible reversibility of alterations of brain electrical activity caused by chronic hypoxia. Normal control group (N = 14) was also examined. Two EEG examinations were done in each groups: at night and in the next morning. Global and regional (left vs. right, anterior vs. posterior) measures of spatial complexity (Omega complexity) were used to characterize the degree of spatial synchrony of EEG. Low resolution electromagnetic tomography (LORETA) was used to localize generators of EEG activity in separate frequency bands. Before CPAP-treatment, a significantly lower Omega complexity was found globally and over the right hemisphere. Due to CPAP-treatment, these significant differences vanished. Significantly decreased Omega complexity was found in the anterior region after treatment. LORETA showed a decreased activity in all of the beta bands after therapy in the right hippocampus, premotor and temporo-parietal cortex, and bilaterally in the precuneus, paracentral and posterior cingulate cortex. No significant changes were seen in control group. Comparing controls and patients before sleep, an increased alpha2 band activity was seen bilaterally in the precuneus, paracentral and posterior cingulate cortex, while in the morning an increased beta3 band activity in the left precentral and bilateral premotor cortex and a decreased delta band activity in the right temporo-parietal cortex and insula were observed. These findings indicate that effect of sleep on EEG background activity is different in OSAS patients and normal controls. In OSAS patients, significant changes lead to a more normal EEG after a night under CPAP-treatment. Compensatory alterations of brain electrical activity in regions associated with influencing sympathetic outflow, visuospatial abilities, long

2016.11.22 Updated Materials Physics and Applications Division Overview Presentation for TV monitor in 3-1415-Lobby

Energy Technology Data Exchange (ETDEWEB)

Duran, Susan M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2016-11-22

These slides are the updated overview presentation for the TV monitor in 3-1415-Lobby at Los Alamos National Laboratory (LANL). It gives an overview of the Materials Physics and Applications Division, including descriptions of the leaders, where researchers are fellows (such as APS or OSA), the newest LANL fellows at MPA, and many other researchers who have won prizes. Finally, MPA's research accomplishments and focuses are detailed.

Enhanced invitation methods to increase uptake of NHS health checks: study protocol for a randomized controlled trial

OpenAIRE

Forster, Alice S; Burgess, Caroline; McDermott, Lisa; Wright, Alison J; Dodhia, Hiten; Conner, Mark; Miller, Jane; Rudisill, Caroline; Cornelius, Victoria; Gulliford, Martin C

2014-01-01

Background NHS Health Checks is a new program for primary prevention of heart disease, stroke, diabetes, chronic kidney disease, and vascular dementia in adults aged 40 to 74 years in England. Individuals without existing cardiovascular disease or diabetes are invited for a Health Check every 5 years. Uptake among those invited is lower than anticipated. Method The project is a three-arm randomized controlled trial to test the hypothesis that enhanced invitation methods, using the Question-Be...

Estructura de una población del árbol Peltogyne purpurea (Cesalpinaceae en un bosque intervenido de la Península de Osa, Costa Rica

Directory of Open Access Journals (Sweden)

Braulio Vílchez

2006-09-01

Full Text Available Se estudió la regeneración de una población del árbol Peltogyne purpurea Pittier después de una corta selectiva de madera en el bosque lluvioso tropical de Mogos, Península de Osa, Costa Rica. La distribución de los árboles adultos de P. purpurea según el diámetro del tallo a la altura del pecho tiene forma de campana. La categoría con la mayor cantidad de individuos correspondió a los árboles con tallos con diámetros entre 70 y 80 cm. No hubo diferencia significativa en el número de brinzales encontrados en los transectos establecidos siguiendo los cuatro puntos cardinales alrededor de los árboles reproductivos (madre. En general, la mayoría de los brinzales se encontraban en los primeros metros alrededor del árbol madre. Se observó otro pico de abundancia de brinzales a la distancia correspondiente con el final de la copa del árbol. La extracción de madera puede tener un efecto negativo en la regeneración de P. purpurea.Population structure of the tree Peltogyne purpurea (Cesalpinaceae in an altered forest at Osa Peninsula, Costa Rica. The regeneration of the rain forest tree Peltogyne purpurea Pittier after selective logging was studied in Mogos, Osa Península, Costa Rica. The distribution of all adult trees of P. purpurea according to diameter at breath height (dbh categories revealed that the distribution of the adult trees followed a bell-shaped curve. The largest number of individuals was found in the 70 to 80 cm dbh category. We did not find any significant differences in the distribution of saplings around seed-producing trees. There were similar numbers of saplings in the four transects established around each reproductive tree following the four cardinal directions. Overall, the majority of the saplings were found in the first meters around each seed-producing tree. There was another peak in the number of saplings at the distance where the crown of the tree ended. Logging can negatively affect the regeneration

Comparison of mailed invitation strategies to improve fecal occult blood test participation in men: protocol for a randomized controlled trial.

Science.gov (United States)

Duncan, Amy; Zajac, Ian; Flight, Ingrid; Stewart, Benjamin J R; Wilson, Carlene; Turnbull, Deborah

2013-07-31

Men have a significantly increased risk of being diagnosed with, and dying from, colorectal cancer (CRC) than women. Men also participate in fecal occult blood test (FOBT) screening at a lower rate than women. This study will determine whether strategies that target men's attitudes toward screening, and matched to stage of readiness to screen, increase men's FOBT participation compared to a standard approach. Eligible trial participants will be a national sample of 9,200 men aged 50 to 74 years, living in urban Australia and randomly selected from the Australian electoral roll. Trial participants will be mailed an advance notification letter, followed 2 weeks later by an invitation letter and a free fecal immunochemical test (FIT) kit. The intervention is a factorial design, randomized controlled trial (RCT) with four trial arms, including a control. The content of the advance notification and invitation letters will differ by trial arm as follows: 1) standard advance notification and standard invitation (control arm); 2) targeted advance notification and standard invitation; 3) standard advance notification and targeted invitation; and 4) targeted advance notification and targeted invitation. The standard letters will replicate as closely as possible the letters included in the Australian National Bowel Cancer Screening Program (NBCSP). Modified advance notification and invitation letters will incorporate additional messages to target men in the precontemplation (advance notification) and contemplation stages (invitation). The primary outcome is return of the completed FIT within 12 weeks of invitation. Analysts will be blinded to trial assignment and participants will be blinded to the use of varying invitational materials. Subsamples from each trial arm will complete baseline and endpoint surveys to measure the psychological impact of the intervention, and qualitative interviews will be conducted to evaluate attitudes toward the intervention. The outcomes of

77 FR 36549 - Nursing Workforce Diversity Invitational Summit-“Nursing in 3D: Workforce Diversity, Health...

Science.gov (United States)

2012-06-19

... Workforce Diversity Invitational Summit--``Nursing in 3D: Workforce Diversity, Health Disparities, and..., Division of Nursing, will host an invitational summit that focuses on Nursing Workforce Diversity (NWD..., thought leaders, and key workforce diversity stakeholders to identify the full range of academic and...

Renewable energies: the choice of invitation to tender candidates for the electric power plants supplied by biomass or biogas

International Nuclear Information System (INIS)

2005-01-01

To contribute to the french objectives of renewable energies development, the Ministry of Industry proposed an invitation to tender for the realization at the first of january 2007 of electric power plants (more than 12 MW) from biomass and biogas. This document presents the selected projects. (A.L.B.)

Invitational Conference on Measurement in Education; Proceedings (of the) Eleventh Southeastern Conference (December 8-9, 1972). Pre-Session.

Science.gov (United States)

Goolsby, Thomas M., Jr., Comp.

Three papers presented at the pre-session to the 11th Invitational Conference on Measurement in Education are provided. These papers are: "Public Schools in Transition. . . One Student Body, Its Needs and Directions" by George R. Rhodes, Jr., "Man to Mankind: The International Dimension of Teacher Education" by David G. Imig, and "Measurement for…

ENS RRFM '97. Transactions. Oral presentations and posters

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-07-01

The four sessions at the first international topical meeting on research reactor fuel management dealt with the following topics: research reactors and fissile materials supply, fuel fabrication, reactor operation and fuel safety, back-end options and transportation. In this book the text of the invited and contributed papers as well as of the posters presented is included.

ENS RRFM '97. Transactions. Oral presentations and posters

International Nuclear Information System (INIS)

1997-01-01

The four sessions at the first international topical meeting on research reactor fuel management dealt with the following topics: research reactors and fissile materials supply, fuel fabrication, reactor operation and fuel safety, back-end options and transportation. In this book the text of the invited and contributed papers as well as of the posters presented is included

A Life in Science - Book release programme invite

Indian Academy of Sciences (India)

MY OF. CE EDUCA. ВРЕМЕ. STION AND. SCIENCE. OF SCIEN. CES. RESEARC,. AN INSTIT она не. A LIFE IN SCIENCE. Penguin Books India. Indian Academy of Sciences and. Indian Institute of Science Education and Research, Bhopal cordially invite you for the release of book. A LIFE IN SCIENCE by C.N.R. Rao.

Composição florística da vegetação arbórea de um trecho de floresta estacional semidecídua em Viçosa, Minas Gerais, e espécies de maior ocorrência na região Floristic composition of trees in a seasonal semidecious forest in Viçosa, Minas Gerais, and species of greater ocurrence in the region

Directory of Open Access Journals (Sweden)

Walnir Gomes Ferreira Júnior

2007-12-01

the qualitative survey of the flora. Thus, this work aimed to determine the floristic composition of a site in the Biological Reserve of the Federal University of Viçosa (UFV in Vicosa-MG, under natural regeneration for 78 years, as well as to establish a comparative analysis with other works in the region, providing information to serve as a basis for further works on recovery and conservation of the biodiversity of seasonal semi deciduous forest sites. The floristic data were obtained by phytosociological sampling in 1 ha, through contiguous plots, with all the wood individuals with stem diameter = 4.7 cm, 1.30m far from the soil were recorded. A total of 130 species was sampled, belonging to 94 genera and 38 botanical families. The analysis of those data combined with other surveys in different sites of the Biological Reserve on the UFV campus showed a remarkable influence of local environmental variables (topography, slopes, sun exposure and water availability on the floristic richness distribution of this site. Casearia decandra, Guapira opposita, Apuleia leiocarpa, Dalbergia nigra, Jacaranda macratha, Matayba elaeagnoides, Piptadenia gonoacantha, Bathysa nicholsonii, Carpotroche brasiliensis, Luehea grandiflora, Mabea fistulifera, Ocotea odorifera, Sorocea bonplandii and Zanthoxylum rhoifolium presented the highest occurrence in the sites studied in the Viçosa region and are recommended for recovery of degraded environments in regions.

Enhanced invitation methods to increase uptake of NHS health checks: study protocol for a randomized controlled trial.

Science.gov (United States)

Forster, Alice S; Burgess, Caroline; McDermott, Lisa; Wright, Alison J; Dodhia, Hiten; Conner, Mark; Miller, Jane; Rudisill, Caroline; Cornelius, Victoria; Gulliford, Martin C

2014-08-30

NHS Health Checks is a new program for primary prevention of heart disease, stroke, diabetes, chronic kidney disease, and vascular dementia in adults aged 40 to 74 years in England. Individuals without existing cardiovascular disease or diabetes are invited for a Health Check every 5 years. Uptake among those invited is lower than anticipated. The project is a three-arm randomized controlled trial to test the hypothesis that enhanced invitation methods, using the Question-Behaviour Effect (QBE), will increase uptake of NHS Health Checks compared with a standard invitation. Participants comprise individuals eligible for an NHS Health Check registered in two London boroughs. Participants are randomized into one of three arms. Group A receives the standard NHS Health Check invitation letter, information sheet, and reminder letter at 12 weeks for nonattenders. Group B receives a QBE questionnaire 1 week before receiving the standard invitation, information sheet, and reminder letter where appropriate. Group C is the same as Group B, but participants are offered a £5 retail voucher if they return the questionnaire. Participants are randomized in equal proportions, stratified by general practice. The primary outcome is uptake of NHS Health Checks 6 months after invitation from electronic health records. We will estimate the incremental health service cost per additional completed Health Check for trial groups B and C versus trial arm A, as well as evaluating the impact of the QBE questionnaire, and questionnaire plus voucher, on the socioeconomic inequality in uptake of Health Checks.The trial includes a nested comparison of two methods for implementing allocation, one implemented manually at general practices and the other implemented automatically through the information systems used to generate invitations for the Health Check. The research will provide evidence on whether asking individuals to complete a preliminary questionnaire, by using the QBE, is effective

Carotenos e provitamina A em bertalha e ervas aromáticas comercializadas em Viçosa, Estado de Minas Gerais, durante as quatro estações do ano = Carotenes and provitamin A in basella and aromatic herbs marketed in Viçosa, Minas Gerais State, during the four seasons of the year

Directory of Open Access Journals (Sweden)

Marina Andrade Batista

2006-01-01

Full Text Available Este estudo teve como objetivos investigar o teor de a-caroteno, b-caroteno e calcular o valor de vitamina A em hortaliças comercializadas no mercado formal e informal de Viçosa, Estado de Minas Gerais, bem como avaliar a influência das quatro estações doano e do local de comercialização sobre o conteúdo desses nutrientes. As hortaliças (bertalha, cebolinha, coentro, manjericão e salsa foram analisadas utilizando-se a cromatografia líquida de alta eficiência (CLAE. Devido ao conteúdo inexpressivo de a-caroteno em todas as amostras, foi possível quantificar apenas o b-caroteno. Não se verificou diferença estatisticamente significativa (a = 0,05 no conteúdo de b-caroteno das hortaliças entre os diferentes estabelecimentos, nem entre as estações do ano. As hortaliçasmostraram-se excelentes fontes de provitamina A, e se consumidas regularmente, contribuem de forma importante na adequação diária de vitamina A para adultos e crianças. Além disso, esses alimentos são acessíveis à população por apresentarem baixo custo e serem facilmente encontrados.This study aimed to investigate the level of a-carotene, b-carotene and to calculate the value of vitamin A in vegetables sold at local markets and informal markets of Viçosa, Minas Gerais State, as wellas to evaluate the seasonal and commercial effects on the content of these pigments. The vegetables (basella, green onion, cilantro, sweet basil and parsley were analyzed through high-performance liquid chromatography (HPLC, being b-carotene the only pigment present in all the analyzed samples. No significant statistical differences (a = 0.05 were found in the contents of b-carotene of the vegetables either among the different stores, or among the different seasons. The vegetables analyzed are great provitamin A sources and, ifeaten on a regular basis, they can fit the daily requirements of vitamin A for adults and children. Besides, these foods are very accessible due to their

Pre- and in-therapy predictive score models of adult OSAS patients with poor adherence pattern on nCPAP therapy

Directory of Open Access Journals (Sweden)

Wang Y

2015-05-01

Full Text Available Yeying Wang,1,2 Alan F Geater,3 Yanling Chai,1 Jiahong Luo,2 Xiaoqun Niu,1 Bing Hai,1 Jingting Qin,1 Yongxia Li1 1Department of Respiratory Medicine, The 2nd Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, People’s Republic of China; 2Department of Epidemiology and Biostatistics, School of Public Health, Kunming Medical University, Kunming, Yunnan Province, People’s Republic of China; 3Epidemiology Unit, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand Objectives: To identify patterns of adherence to nasal continuous positive airway pressure (nCPAP use in the first 3 months of therapy among newly diagnosed adult patients with obstructive sleep apnea/hypopnea syndrome (OSAS and their predictors. To develop pretherapy and in-therapy scores to predict adherence pattern. Methods: Newly diagnosed adult OSAS patients were consecutively recruited from March to August 2013. Baseline clinical information and measures such as Epworth Sleepiness Scale (ESS, Fatigue Severity Scale (FSS, Zung’s Self-Rating Depression Scale (SDS, and The Pittsburgh Sleep Quality Index (PSQI at baseline and at the end of 3rd-week therapy were collected. Twelve weeks’ adherence data were collected from the nCPAP memory card, and K-means cluster analysis was used to explore adherence patterns. Predictive scores were developed from the coefficients of cumulative logit models of adherence patterns using variables available at baseline and after 3 weeks of therapy. Performance of the score was validated using 500 bootstrap resamples. Results: Seventy six patients completed a 12-week follow-up. Three patterns were revealed. Patients were identified as developing an adherence pattern that was poor (n=14, mean ± SD, 2.3±0.9 hours per night, moderate (n=19, 5.3±0.6 hours per night, or good (n=43, 6.8±0.3 hours per night. Cumulative logit regression models (good → moderate → poor revealed independent baseline

Survey report. New energy vision formulation project for Osa Town, Okayama Prefecture; 2001 nendo Osa cho shin energy vision sakutei tou jigyo chosa hokokusho. Chiiki shin energy vision sakutei tou jigyo

Energy Technology Data Exchange (ETDEWEB)

NONE

2002-02-01

A New Energy Vision was formulated for Osa Town after investigations about energy demand, new energy reserves, and their available amounts. The town consumes approximately 50.6-billion kcal in total, with automobiles consuming a half thereof as fuel. Studies were made about new energy reserves and recoverable amounts in the town, and then an estimation was made that 16.2 times 10{sup 5} kWh/year would be recoverable from photovoltaic energy, 1.58 times 10{sup 5} kWh from small-scale hydropower, 8.79 times 10{sup 6} kWh from ligneous biomass, and 1.96 times 10{sup 5} kWh from livestock biomass, and that 40 MW, for example, would come from wind power, subject to change depending on the wind power generator system to be built. Projects for new energy introduction were discussed, which involved the use of biodiesel fuel for official vehicles, installation of solar hot water showers in primary and junior high schools, application of photovoltaic/wind power to crime prevention lights and street lamps, snow melting systems for roads utilizing geothermal energy, use of heat from thinnings and ligneous waste, wind power facilities, small-scale hydropower facilities, introduction of new energy appliances into sightseeing facilities, and the introduction of photovoltaic power or the like into public facilities. (NEDO)

Ocorrência da síndrome da apneia obstrutiva do sono (SAOS em crianças respiradoras orais Obstructive sleep apnea syndrome (OSAS in mouth breathing children

Directory of Open Access Journals (Sweden)

Suemy Cioffi Izu

2010-10-01

Full Text Available É bem estabelecido que a respiração oral em crianças está relacionada à hipertrofia adenoamigdaliana, que é a principal causa de apneia do sono nesta população. Apesar da importância deste tema, há poucos estudos que comprovam a relação entre SAOS e respiração oral. OBJETIVO: Determinar a prevalência de distúrbios respiratórios do sono em crianças respiradoras orais e sua correlação com achados otorrinolaringológicos. MATERIAL E MÉTODO: Foram avaliados retrospectivamente 248 prontuários de crianças respiradoras orais do serviço de Otorrinolaringologia Pediátrica de uma grande instituição entre 2000 e 2006, analisando os achados otorrinolaringológicos, polissonografia, nasofibroscopia e/ou radiografia em perfil do Cavum. O principal dado polissonográfico utilizado foi o índice de apneia (IA. Classificou-se como ronco primário aqueles com IA1. Desenho Científico: Coorte retrospectivo. RESULTADOS: Dos 248 pacientes incluídos, 144 (58% apresentavam ronco primário e 104 (42% apresentavam SAOS. Os achados otorrinolaringológicos mais frequentes foram Hipertrofia adenoamigdaliana (n=152; 61,2%, Hipertrofia de tonsila palatina (n=17; 6,8% Hipertrofia da tonsila faríngea (n=37; 14,9%, Rinite Alérgica (n=155; 62,5% e Otite Secretora (36; 14,5%. CONCLUSÕES: Ronco Primário e SAOS são frequentes em crianças respiradoras orais. A afecção otorrinolaringológica mais encontrada em crianças com SAOS é a hipertrofia adenoamigdaliana acompanhada ou não de rinite alérgica.It is well known that mouth breathing is associated with adenotonsillar hypertrophy - which is the main cause of obstructive sleep apnea among children. Despite the importance of this matter, there are only a handful of studies showing the relationship between OSAS and mouth breathing. AIM: to determine the prevalence of obstructive sleep disorders in mouth breathing children and study its correlation with otorhinolaryngological findings. STUDY

La protección al consumidor por publicidad engañosa en el Ecuador y sus limitaciones legales de acuerdo a la legislación vigente

OpenAIRE

Guerra Naranjo, Marco Vinicio

2006-01-01

El ámbito comercial, inmensamente competitivo de proveedores de bienes y servicios y la masificación de sus ventas ha llevado a que se utilice con mayor frecuencia estrategias que implican el uso de publicidad agresiva y falsa, que tiende a perjudicar a los consumidores, quienes adquieren bienes y servicios, distintos a los que fueron publicitados o promocionados por cualquier medio, vulnerando con ello sus derechos con la ilícita publicidad engañosa. Por el contrario, el em...

Presenting Critical Space Weather Information to Customers and Stakeholders (Invited)

Science.gov (United States)

Viereck, R. A.; Singer, H. J.; Murtagh, W. J.; Rutledge, B.

2013-12-01

Space weather involves changes in the near-Earth space environment that impact technological systems such as electric power, radio communication, satellite navigation (GPS), and satellite opeartions. As with terrestrial weather, there are several different kinds of space weather and each presents unique challenges to the impacted technologies and industries. But unlike terrestrial weather, many customers are not fully aware of space weather or how it impacts their systems. This issue is further complicated by the fact that the largest space weather events occur very infrequently with years going by without severe storms. Recent reports have estimated very large potential costs to the economy and to society if a geomagnetic storm were to cause major damage to the electric power transmission system. This issue has come to the attention of emergency managers and federal agencies including the office of the president. However, when considering space weather impacts, it is essential to also consider uncertainties in the frequency of events and the predicted impacts. The unique nature of space weather storms, the specialized technologies that are impacted by them, and the disparate groups and agencies that respond to space weather forecasts and alerts create many challenges to the task of communicating space weather information to the public. Many customers that receive forecasts and alerts are highly technical and knowledgeable about the subtleties of the space environment. Others know very little and require ongoing education and explanation about how a space weather storm will affect their systems. In addition, the current knowledge and understanding of the space environment that goes into forecasting storms is quite immature. It has only been within the last five years that physics-based models of the space environment have played important roles in predictions. Thus, the uncertainties in the forecasts are quite large. There is much that we don't know about space

ENS RRFM '97. Transactions. Oral presentations and posters

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-07-01

The four sessions at the first international topical meeting on research reactor fuel management dealt with the following topics: research reactors and fissile materials supply, fuel fabrication, reactor operation and fuel safety, back-end options and transportation. In this book the text of the invited and contributed papers as well as of the posters presented is included.

Inviting Dialogue: An Alternative to Teaching in the Dark.

Science.gov (United States)

Fox, Patricia Shelley

1998-01-01

Uses illustrations from a graduate seminar in the teaching of writing, a high school classroom, and a seventh-grade classroom to show the value of teacher-student dialog over teacher monologue, and to show teacher responses that resist the impulse to launch into the teacher's monologue, and instead invite dialog and turn the work of meaning-making…

The "DOC" screen: Feasible and valid screening for depression, Obstructive Sleep Apnea (OSA) and cognitive impairment in stroke prevention clinics.

Science.gov (United States)

Swartz, Richard H; Cayley, Megan L; Lanctôt, Krista L; Murray, Brian J; Cohen, Ashley; Thorpe, Kevin E; Sicard, Michelle N; Lien, Karen; Sahlas, Demetrios J; Herrmann, Nathan

2017-01-01

Post-stroke Depression, Obstructive sleep apnea (OSA) and Cognitive impairment ("DOC") are associated with greater mortality, worse recovery and poorer quality of life. Best practice recommendations endorse routine screening for each condition; yet, all are under-assessed, diagnosed and treated. We seek to determine the feasibility and validity of an integrated tool ("DOC" screen) to identify stroke clinic patients at high-risk of depression, OSA, and cognitive impairment. All consecutive new referrals to a regional Stroke Prevention Clinic who were English-speaking and non-aphasic were eligible to be screened. Time for screen completion was logged. DOC screen results were compared to the neuropsychological battery and polysomnogram assessments using a modified receiver operator characteristic and area under the curve analysis. Data is reported to conform to STARD guidelines. 1503 people were screened over 2 years. 89% of eligible patients completed the screen in 5 minutes or less (mean 4.2 minutes), less than half the time it takes to complete the Montreal Cognitive Assessment (MoCA). 437 people consented to detailed testing. Of those, 421 completed the Structured Clinical Interview for Depression within 3 months of screening, 387 completed detailed neuropsychological testing within 3 months, and 88 had overnight polysomnograms. Screening scores combined with demographic variables (age, sex, education, body mass index), had excellent validity compared to gold standard diagnoses: DOC-Mood AUC 0.90; DOC-Apnea AUC 0.80; DOC-Cog AUC 0.81. DOC screen scores can reliably categorize patients in to low-, intermediate- or high-risk groups for further action and can do so with comparable accuracy to more time-consuming screens. Systematic screening of depression, obstructive sleep apnea, and cognitive impairment in 5 minutes or less is feasible and valid in a high volume stroke clinic using the DOC screen. The DOC screen may facilitate improved identification and treatment

Flutuação populacional de espécies de cigarrinhas transmissoras da clorose variegada dos citros (CVC em Viçosa-MG Population dynamics of sharpshooters species transmitter of citrus variegated chlorosis (CVC in Viçosa-MG

Directory of Open Access Journals (Sweden)

Dierlei dos Santos

2005-08-01

Full Text Available Os objetivos deste trabalho foram avaliar a presença e a dinâmica populacional, ao longo do ano, de cigarrinhas transmissoras da CVC, no município de Viçosa - MG. As coletas foram realizadas no período de agosto de 2003 a julho de 2004, com auxílio de armadilhas adesivas amarelas e com rede entomológica (puçá. Das onze espécies comprovadamente capazes de transmitir a CVC, foram encontradas nove. O número total de cigarrinhas capturadas foi de 2.966, sendo 2.805 nas armadilhas e 161 no puçá. As três espécies da família Cicadellidae mais expressivas em número de insetos foram Bucephalogonia xanthophis (36,6% capturados na rede entomológica e 34,7% na armadilha, Dilobopterus costalimai (9,9% capturados na rede entomológica e 11,3% na armadilha e Acrogonia citrina (6,8% capturados na rede entomológica e 7,4% na armadilha. No mês de novembro, foram coletadas 378 cigarrinhas, correspondendo ao mês de maior incidência, sendo que 292 dessas foram coletadas na primeira quinzena, concorrendo para um pico populacional. Não houve diferença significativa entre o número médio de cigarrinhas coletadas no interior e na periferia da área.The objectives of this work were to evaluate the presence and the population dynamics of Citrus CVC transmitter sharpshooters along the year in the municipality of Viçosa- MG. The sharpshooter populations were monitored in the period of August 2003 to July 2004 using yellow adhesive traps and entomologic nets. During this period 2966 sharpshooters were captured and identified. Among eleven species known as CVC transmitters, nine were found in the region. The three most expressive species in number found were Bucephalogonia xanthophis (36,6% captured in entomological net and 34,7% in the trap, Dilobopterus costalimai (9,9% captured in entomological net and 11,3% in the trap and Acrogonia citrina (6,8% captured in entomological net and 7,4% in the trap. The largest incidence of sharpshooters occurred

INVITATION to CERN pensioners and personnel

CERN Multimedia

DG Unit

2009-01-01

The Swiss Foundation for Research into Ageing, AETAS, will be holding its research award ceremony at CERN on Wednesday 10 June 2009. You are cordially invited to attend the ceremony and, in particular, a lecture given by Professor Osman RATIB Professor of Medicine, Head of the Department of Medical Imaging and Medical Informatics and Head of the Division of Nuclear Medicine at the University Hospital of Geneva "Progress in medical imaging" WEDNESDAY 10 JUNE 2009 AT 5:00 P.M. CERN MAIN AUDITORIUM (Bldg.500) The lecture will be followed by a discussion moderated by Professor Jean-Pierre Michel, President of the AETAS Foundation. Refreshments will be offered by the Foundation

INVITATION to CERN pensioners and personnel

CERN Multimedia

GS Department

2009-01-01

The Swiss Foundation for Research into Ageing, AETAS, will be holding its research award ceremony at CERN on Wednesday 10 June 2009. You are cordially invited to attend the ceremony and, in particular, a lecture given by Professor Osman RATIB Professor of Medicine, Head of the Department of Medical Imaging and Medical Informatics and Head of the Division of Nuclear Medicine at the University Hospital of Geneva "Progress in medical imaging" WEDNESDAY 10 JUNE 2009 AT 5.00 P.M. CERN MAIN AUDITORIUM, (Bldg.500) The lecture will be followed by a discussion moderated by Professor Jean-Pierre Michel, President of the AETAS Foundation. Drinks will be offered by the Foundation

Proceedings of the symposium on nuclear physics: Invited talks/Seminars. Vol. 34A(1991)

International Nuclear Information System (INIS)

Kailas, S.; Singh, P.

1992-01-01

The proceedings volume contains the invited talks delivered at the Symposium on Nuclear Physics held at Bombay during 26-30 December 1991. These talks dealt with the some of the front line areas of nuclear physics. They are: influence of nuclear dynamics on measurements of the fission fragment angular distribution in heavy ion induced fusion-fission reactions, stability of hot nuclei formed in violent nuclear collisions limited mainly by temperature, resonant behaviour in heavy ion reactions and the structural connection of high-lying states with the specific low-lying states initiated through particle decay, co-existence of different shapes in the same nuclei, evidence for deformed nucleons, pre-fission measurements in heavy ion induced fusion-fission experiments and influence of these neutrons in slowing down fission process, leptodermous expansion techniques for explaining various physical properties of nuclei, and giant resonances in hot rotating nuclei. Two seminars were also held in the symposium. One was on heavy ion reactions below and near the Coulomb barrier and the other one was on quark-gluon plasma. The papers presented at these seminars are also included in the book. The above mentioned invited talks and seminar papers have been processed separately for inclusion in the INIS Database. (N.B.)

Risky consumption habits and safety of fluid milk available in retail sales outlets in Viçosa, Minas Gerais State, Brazil.

Science.gov (United States)

Pieri, Fabio Alessandro; Colombo, Monique; Merhi, Carolina Milner; Juliati, Vinícius Augusto; Ferreira, Marcello Sebe; Nero, Marcelo Antônio; Nero, Luis Augusto

2014-06-01

This study aimed to assess raw milk consumption habits in the urban population of Viçosa, Minas Gerais, Brazil, and the microbiological safety and quality of the fluid milk available in retail sales outlets in the same region. A simplified questionnaire regarding raw milk consumption was applied to the persons responsible for food acquisition in 411 residences. The regular consumption of raw milk was observed by 18.5% of the interviewers, and lack of knowledge of possible risks related to this food product. Microbiological safety and quality were assessed for raw (n=69), pasteurized (n=80), and ultra-high-temperature (UHT)-treated milk (n=80) by analyzing the counts of mesophilic aerobes, coliforms, and Escherichia coli, and detection of Listeria monocytogenes and Salmonella spp.; raw milk samples were also subjected to enumeration of coagulase-positive Staphylococcus. Concerning raw milk, 59.4% of the samples were considered as produced in inadequate hygienic conditions, 5.8% of the samples presented counts of coagulase-positive Staphylococcus lower than 100 colony-forming units (CFU)/mL, and no samples presented with positive results for L. monocytogenes or Salmonella spp. All pasteurized and UHT milk samples presented with low counts of mesophilic aerobes and coliforms, while L. monocytogenes and Salmonella spp. were absent. The data demonstrated that raw milk was consumed by the population studied. Despite the absence of potential hazards, raw milk was of poor hygienic quality, in contrast with the processed fluid milk available in retail sales outlets that was safe and of good hygienic quality, highlighting the suitability of pasteurized and UHT milk for human consumption.

Avaliação do perfil de trabalhadores e das condições de trabalho em marcenarias no município de Viçosa-MG Evalution of workers' profile and work conditions joineries in Viçosa, Minas Gerais, Brazil

Directory of Open Access Journals (Sweden)

Kátia Regina Silva

2002-11-01

Full Text Available Esta pesquisa foi desenvolvida nos ambientes de trabalho de marcenarias localizadas no município de Viçosa, Minas Gerais, para realizar o levantamento do perfil dos trabalhadores e das condições de trabalho relacionadas às atividades exercidas em marcenarias, visando a melhoria da saúde, do bem-estar, da segurança, do conforto e da produtividade dos trabalhadores. O levantamento do perfil dos trabalhadores e das condições de trabalho foi realizado por intermédio da aplicação de questionários aos trabalhadores das marcenarias avaliadas e das observações e anotações realizadas durante a coleta dos dados. Pelos resultados obtidos, foram constatados diversos problemas relacionados aos marceneiros, como, por exemplo, cansaço, dores nas pernas e na coluna, alergia devido à utilização de produtos químicos e ao pó da madeira, falta de treinamento para exercer a profissão e praticamente nenhuma noção sobre segurança e higiene no trabalho. A incidência de acidentes relatados foi baixa; as mãos foram as partes mais afetadas por cortes leves, não tendo sido relatado nenhum tipo de acidente grave. Pôde-se constatar também que há necessidade de conscientizar os proprietários das marcenarias sobre a importância e os benefícios da segurança e higiene no trabalho para os seus funcionários.This work was carried out in joineries located in Viçosa, Minas Gerais, Brazil, to survey the profile of workers and work conditions related to the activities performed, aiming to promote health, welfare, safety, comfort and productivity of the workers. This survey was carried out by means of the application of questionnaires to the workers and from observations made during data collection. According to the obtained results, various problems related to the joiners were observed, such as fatigue, pain in legs and spine, allergies due to the use of chemicals and sawdust, lack of training for the work and almost none knowledge about work

Adhering to the assumptions of invitational education: a case study ...

African Journals Online (AJOL)

South African schools are constantly faced with evolving needs and challenges characterised by change. As in other countries, schools in South Africa encounter pressure to 'produce more for less' and at the same time to achiev e c ertain goals and standards. Transforming schools into inviting institutions requires a ...

The Effect of the Transition to Home Monitoring for the Diagnosis of OSAS on Test Availability, Waiting Time, Patients’ Satisfaction, and Outcome in a Large Health Provider System

Directory of Open Access Journals (Sweden)

Ahmad Safadi

2014-01-01

Full Text Available During 2009, the Haifa district of Clalit Health Services (CHS has switched from in-lab polysomnography (PSG to home studies for the diagnosis of obstructive sleep apnea (OSA. We assessed the effects of this change on accessibility, waiting time, satisfaction, costs, and CPAP purchase by the patients. Data regarding sleep studies, CPAP purchase, and waiting times were collected retrospectively from the computerized database of CHS. Patients’ satisfaction was assessed utilizing a telephone questionnaire introduced to a randomized small sample of 70 patients. Comparisons were made between 2007 and 2008 (in-lab PSGs and 2010 and 2011 (when most studies were ambulatory. Of about 650000 insured individuals in the Haifa district of CHS, 1471 sleep studies were performed during 2007-2008 compared to 2794 tests during 2010-2011. The average waiting time was 9.9 weeks in 2007-2008 compared to 1.1 weeks in 2010-2011 (P<0.05. 597 CPAPs were purchased in 2007-2008 compared to 831 in 2010-2011. The overall patients’ satisfaction was similar, but discomfort tended to be higher in the in-laboratory group (4.1 vs 2.7 in a scale of 0–10; P=0.11. Switching to ambulatory diagnosis improved the test accessibility and reduced the waiting times. Patients’ satisfaction remained similarly high. The total direct cost of OSA management was reduced.

Composição florística de uma floresta estacional semidecidual montana no município de Viçosa-MG Floristic composition of a montane seasonal semideciduous tropical forest in Viçosa, MG, Brasil

Directory of Open Access Journals (Sweden)

João Augusto Alves Meira-Neto

2002-08-01

Full Text Available O objetivo do presente estudo foi investigar a composição florística arbórea da Mata da Silvicultura (20º45'S e 42º55'W, município de Viçosa, Zona da Mata de Minas Gerais, com o intuito de avaliar sua similaridade com outras florestas. Para comparação florística foi utilizada a análise de agrupamentos pelo método de médias aritméticas não-ponderadas (UPGMA, a partir dos índices binários de similaridade de Sørensen entre as florestas comparadas. Foram relacionadas 154 espécies de 47 famílias botânicas para a Mata da Silvicultura. Esta mata mostrou-se mais similar às florestas semideciduais de altitude de Lavras (MG e de Atibaia (SP e menos similar às florestas submontanas e litorâneas. Estes resultados evidenciam uma importante influência das temperaturas na determinação do tipo florístico das florestas do Sudeste e Sul brasileiros.This study aims to investigate the floristic composition of the Silvicultura forest (20º45`S and 42º55´W by comparing it to other forest compositions. Thus, the cluster analysis method of unweighted pair-group using arithmetic averages (UPGMA was used, applying the Sørensen binary similarity index found among compared forests. A list of 154 species of 47 families was recorded. The Silvicultura forest is more similar to the montane semideciduous forests of Lavras and Atibaia, but less similar to submontane and coastal forests. These results show that temperature plays an important role in the floristic differentiation of the southern and southeastern Brazilian forest types.

Regeneração pós-fogo em um fragmento de floresta estacional semidecidual no município de Viçosa, MG

Directory of Open Access Journals (Sweden)

Sebastião Martins Venâncio

2002-01-01

Full Text Available Estudou-se a vegetação colonizadora seis meses após perturbação por fogo, em uma á rea do Campus da Universidade Federal de Viçosa, em Viçosa (20o 45’ S, 42o 51’ W , MG. A á rea total de floresta secundá ria atingida por incê ndio foi de 12 hectares, apresentando níveis diferenciados de destruição da vegetação. O estudo concentrou-se no trecho onde o efeito do fogo foi mais drá stico, com a destruição total da cobertura vegetal. Dentro da á rea de estudo, foram comparadas duas toposseqüê ncias de relevo: côncavo (ravina e convexo (crista. Em cada toposseqüê ncia, foram instaladas dezoito parcelas contíguas de 5x5 m, totalizando 36 parcelas, nas quais foram identificadas todas as plantas vasculares. No total, foram amostradas 75 espécies, pertencentes a 26 famílias. As famílias mais ricas em espécies foram: Asteraceae (14, Poaceae (10, Malvaceae (7 e Fabaceae (6. Na toposseq üê ncia crista as espécies com maior valor de cobertura foram: Sida carpinifolia seguida de Melinis minutiflora, Diodia alata e Eupatorium laevigatum, e na ravina: Melinis minutiflora, Eupatorium laevigatum, Sida carpinifolia e Sidastrum paniculatum. Todas as parcelas apresentaram mais de 90% da á rea coberta por vegetação herbá cea e subarbustiva, destacando a importâ ncia dessa vegetação inicial na proteção do solo contra processos erosivos em relevos acidentados.

"First Convention of Lunar Explorers" - Invitation to the media

Science.gov (United States)

2001-03-01

The first LUNEX Convention will bring together lunar explorers from all backgrounds, including professionals, amateur space enthusiasts and interested visitors from the public. During the Convention numerous oral presentations will prompt detailed discussions on all aspects of future lunar exploration: the Moon as a geology laboratory or an astronomical platform; the knowledge of lunar geography needed to land and move on the surface; the implications of finding water-ice on the Moon and whether this might be detected by forthcoming missions; the architecture of lunar habitats; what would be needed in the future for the Moon to support life; cultural and social aspects; and the scientific motivation for returning to the Moon. The Convention will also be the main public event in 2001 at which SMART-1 is presented. SMART-1, due to be launched in 2002 will test solar electric propulsion and other innovative approaches for future deep space probes. It is the first European satellite to be sent towards the Moon. Visitors to the Palais de la Découverte will be able to view a model of SMART-1. On 9 March, at 09:00, the media is invited to hear about the LUNEX objectives and activities and to learn about the European Space Agency’s SMART-1 mission within the broader context of ESA’s Planetary Exploration Programme. Background information on LUNEX The Lunar Explorers Society (LUNEX) is an international organization created by 200 founder members in July 2000. LUNEX was founded at the end of the 4th Conference on Exploration and Utilisation of the Moon (ICEUM4), organised by ESA and the International Lunar Exploration Working Group (ILEWG). Its aim is to promote the exploration of the Moon for the benefit of humanity, bridging the gap between space agencies and the general public to promote planetary exploration and space. The Lunar Explorers Society invites all interested individuals to become members. Background information on SMART-1 SMART-1 is the first of ESA�

Invited series of talks and lectures at Yale University (USA) on Rolf Nordahl's research

DEFF Research Database (Denmark)

Nordahl, Rolf

2010-01-01

in several topics. The lectures will address his innovative experiments on using methods from Film and Filmsound to inform research in Computer Games and Virtual Reality applications with real-life examples from the Natural Interactive Walking (NIW) project - a EU-funded project headed at Aalborg University......Rolf Nordahl , Medialogy in Copenhagen, will be giving an invited series of lectures at Yale University, Connecticut, USA in the last week of March, 2010. Rolf has been invited to give talks to Professors, research fellows, Ph.D.'s and graduate students of Yale University (USA), on his research...

The Intimate Correlation of Invitational Education and Effective Classroom Management

Science.gov (United States)

Riner, Phillip S.

2003-01-01

Critics of Invitational Education and other self-concept approaches to learning have long argued that there is a lack of empirical data to support the claims that approaches to student instruction based on self-concept theory are central to effective learning. Ellis (2001) examines a number of these analyses where self-concept, self-esteem, and…

More playful user interfaces: interfaces that invite social and physical interaction

NARCIS (Netherlands)

Nijholt, Antinus; Unknown, [Unknown

2015-01-01

This book covers the latest advances in playful user interfaces – interfaces that invite social and physical interaction. These new developments include the use of audio, visual, tactile and physiological sensors to monitor, provide feedback and anticipate the behavior of human users. The decreasing

The Archeomagnetic field in South America: Present status and perspectives (Invited)

Science.gov (United States)

Hartmann, G. A.; Trindade, R. I.; Gallet, Y.; Poletti, W.; Begnini, G. S.; Genevey, A.; Legoff, M.

2013-12-01

Geomagnetic field variations over decadal to millennial timescales can be determined from direct (i.e. observatory) and indirect (e.g. from archeological artifacts and volcanics) sources. Before the observatory era, the recovery of these variations is however still strongly penalized by the very uneven both geographical and temporal distributions of the available archeo/paleomagnetic dataset. In particular, the southern hemisphere contributes with only ~3% of the global archeomagnetic database. Moreover, most of these data present restrictions due to their poor experimental reliability and to the lack of good age control. Therefore, new intensity and directional data from the southern hemisphere are strongly requested for the next generation of archeomagnetic field models. In this presentation, we will report on intensity and inclination results obtained from different regions in Brazil. A collection of twenty-three site-mean archeointensity data were obtained by our team from architectural brick fragments dated to the past 500 years from Northeast and Southeast Brazil. This dataset was complemented by a series of new results from South Brazil. In addition, we also obtained inclination data, after reconstructing the firing position of the ancient bricks from modern analogs of historical brickyards. Thirteen site-mean inclination results dated to between 1790 AD and 1950 AD and five inclination results spanning the 1590-1920 AD time interval were so determined from Southeast and Northeast Brazil, respectively. Altogether, our data, which are geographically distributed over more than 20 degrees in latitude, allow us to discuss the large-scale influence in Brazil and South America of non-dipolar features of the geomagnetic field during the past few centuries.

Diagnosis of health-related physical fitness in office workers of the Federal University of Viçosa

Directory of Open Access Journals (Sweden)

Cristiano Diniz da Silva

2004-06-01

Full Text Available The behavioral demands and the particularities of the activities performed by the employees from offices at the Federal University of Viçosa can offer a series of negative factors for health. The interface with the computer and task characteristics give a great body and also cognitive demands, that allied to several factors can represent the appearance or worsening repetitive lesions and/or work related problems in the skeletal muscle (Cumulative Trauma Disorders . This study aimed to diagnose the workers’ situation in relation to General Human Factors (GHF and level of Health-Related Fitness (HRFcomponents: cardiorrespiratory; flexibility; strength and percent of body fat. The sample was composed by 46 workers. For both sexes, the GHF variables of higher significance were: “posture perception”; “sensation of local pains and those from some movement or task” in the back, shoulders and arms areas. Referring to HRF, both sexes presented unsatisfactory levels for trunk-hip flexibility “ and great part of men were classified as” below average “ in the push-up test” which are risk factors for CTD. Significant portion of them presented high percent of body fat (25,0% or were “obese” (14,2%. In general terms of HFR, there should be interventions, such as physical activity and/or sports programs for this group of employees at this institution. It is suggested that actions should also be taken in the leisure activity offering, once it was shown that 39,2% of the men and 44,4% of the women have in TV their main leisure activity. RESUMO As exigências comportamentais e as particularidades das atividades desenvolvidas pelos funcionários de alguns setores caracterizados como escritórios da Universidade Federal de Viçosa podem estar potencializando uma série de fatores negativos para a saúde destes. A interface com o computador e a característica da tarefa levam a uma forte exigência física e também cognitiva, que aliadas a

Invited by God onto the worship stage: Developing missional communities through participation in Theo-drama

Directory of Open Access Journals (Sweden)

Ian A. Nell

2013-02-01

Full Text Available When the front of the church begins to resemble a stage and the preacher, musicians and other leaders act like performers whilst the congregation takes on the role of an audience, then something is wrong with worship. But not only with worship: something is wrong with the church. A church longing to be missional � that is, a church in which all Christians are participants in the mission of God � needs to express that participation in its worship. Theological dramatic theory shows us how the Trinity acts out a grand narrative in creation, redemption and glorification, and invites us to participate in the Story being performed. This same narrative can be present in worship and can invite our immediate participation. But this cannot happen if either God or the congregation is relegated to the role of mere audience. However, when the Story is told and performed in worship and when the worshipping community is able to participate alongside the Trinity in the Theo-drama of worship, then worship takes on the ability to form that community missionally. Worship is a habit repeated week after week; therefore, its power to transform a community into a missonal congregation is immense.

STUDY OF THE SITUATION OF MASS MOVEMENTS IN THE URBAN AREA OF VIÇOSA (MG

Directory of Open Access Journals (Sweden)

Fernando Lucci Resende de Souza

2005-05-01

Full Text Available The understanding of the relief goes by something larger than the observation at the way, understanding several other factors as climate, soil types and vegetable covering. However, the forms of the relief interfere as one of the main components of the atmosphere,being necessary its knowledge for the understanding of the dynamics of the area research object.The agreement of the relief passes for something more important that the comment of its form, understanding several other factors as climate, soil types and vegetal covering. However, the forms of the relief are inserting as the one of the main components of theenvironment, being necessary its knowledge for the agreement of the dynamic of the area research object.This knowledge is indispensable, because it is impossible to repress the occupation expansion of the spaces and much less to restraint environmental impacts caused by the men and the nature is not capable to regenerate all of the damaged spaces in a short space of time.Many of the inhabited spaces are fruits of segregation, which would be consequence of the exclusion that the effective economical system imposes to the people and spaces. On the other hand, the environmental problems are not correlated only with outlying neighborhoods, but they come very visible in places where constructions of high purchasing power prevail. But, one thing we can do is to prevent, the areas that are not busy, because it is viable naturally,environmentally and less expensive economically speaking. It is in this context, which the study of the mass movements can be of vital importance. The present work seeks to characterize the mass movements that happen in the urban area of Viçosa, with the objective to relate and to compare the rising done in the urban area of the municipal district at the scale 1: 5000 for Vieira in the year of 2000, in order to verify the evolution of the areas studied by the referred author, being analyzed these progressed or some

A Dystopian Study of Invitation to a Beheading by Vladimir Nabokov

Directory of Open Access Journals (Sweden)

Faruk KALAY

2014-12-01

Full Text Available Utopia meaning a good place in Greek is a term coined in the fictive book Utopiaby Thomas More depicting an ideal place where people prosperously live. As a reaction and antithesis to this term, dystopia is defined as "an imaginary place where people lead dehumanized and often fearful lives" in Merriam-Webster Dictionary. Hence, Invitation to a Beheading authored by Nabokov recounts a protagonist named Cincinnatus C. sentenced to death for 'the farcical crime' (Morgan 2003: 281 of 'gnostic turpitude' which has a sarcastic and awaits for his punishment in an eccentric cell. On waiting, Cincinnatus not knowing his executioner and when the execution will be held is introduced by the manager trying to be a friend of the protagonist. In this context, when studied from the dystopian point of view, the novel has a great numbers of dystopian characteristics. In this study, the term of dystopia and the characteristics of this term in Invitation to a Beheading will be argued.

Fast reactor safety and related physics. Volume I. Invited papers; panels; summary

Energy Technology Data Exchange (ETDEWEB)

1976-01-01

Separate abstracts were prepared for each of the twenty invited papers included. The papers covered sessions on licensing aspects of safety design bases, safety of demonstration plants, safety aspects of large commercial fast breeders, and safety test facilities.

Algunas plantas leñosas del Trapecio Amazónico Colombiano

Directory of Open Access Journals (Sweden)

Dugand Armando

1956-09-01

Full Text Available La lista de plantas que compone este breve artículo fue confeccionada extrayendo los datos respectivos de la obra "Woods of Northeastern Peru" de Llewelyn Williams, publicada en FIELD MUSEUMOF NATURAL, HISTORY,BOTANICALSERIES, Vol. 15, pp. 1-509; 1936. En dicha obra el señor Williams cataloga -entre muchas otras de distintas regiones de la Amazonia peruana-- un buen numero de plantas leñosas coleccionadas por él en la hacienda "La Victoria", muy cerca de Leticia, haciéndolas figurar como del Perú. Esto se debe a que en la época que Williams visito aquella región hoy colombiana -a mediados de 1929- no se había perfeccionado todavía, o mejor dicho, no se había puesto en práctica (aunque ya estaba promulgado solemnemente el tratado de fronteras entre Colombia y el Perú que puso fin al litigio que estos dos países sostuvieron por más de un siglo sobre una gran parte del territorio selvoso que se extiende entre los ríos Caquetá y Amazonas. Digo que no se había puesto en practica dicho tratado porque, si bien se firmó el 24 de marzo de 1922 y se promulgo el 31 de marzo de 1938, sólo vino a ejecutarse in situ el 17 de agosto de 1930, después de localizada y amojonada la frontera, mediante la formalidad del acto de entrega y de recibo de los territorios que les tocó definitivamente a un país y al otro. Fue, pues, un año después de la visita de Williams a dicha región cuando la bandera y las autoridades colombianas reemplazaron efectivamente a las peruanas en el llamado "Trapecio Amazónico", cuya población principal es Leticia, sobre el rio Amazonas.

Floristic composition of natural regeneration of tree species in a mountain seasonal semideciduous florest fragment over an eigth year period, in Viçosa, MG, Brazil

OpenAIRE

Higuchi, Pedro; Reis, Maria das Graças Ferreira; Reis, Geraldo Gonçalves dos; Pinheiro, Antonio Lelis; Silva, Crodoaldo Telmo da; Oliveira, Carlos Henrique Rodrigues de

2006-01-01

A florística da regeneração natural foi estudada em 10 locais, com seis sub-parcelas em cada local, em 1992, 1995 e 2000, em fragmento de Floresta Estacional Semidecidual Montana, em Viçosa, MG. A amostragem da classe 1 de tamanho de planta (até 1 m de altura), classe 2 (1-3 m de altura) e classe 3 (>3 m de altura e 3m and DBH < 5cm). A total of 4,149 individuals were sampled over the inventory period, comprising 42 families and 160 species, being 11.7 % pioneer, 62.1 % early secondary, and ...

Equação de biomassa e estoque de carbono do pinhão manso, no município de Viçosa, MG Biomass equation and carbon stock of jatropha crop, in Viçosa, Minas Gerais, Brazil

Directory of Open Access Journals (Sweden)

Diego de Paula Toledo

2012-11-01

Full Text Available O presente trabalho teve como objetivo estimar equações de biomassa e o estoque de carbono da cultura do Pinhão Manso (Jatrophacurcas L.. A área estudada localiza-se no município de Viçosa, MG. O plantio foi realizado em espaçamento 3,5x3,0m, em 4,64ha. Para quantificação da biomassa, foi utilizado o método direto e destrutivo, aplicado às árvores-amostra, que foram selecionadas de acordo com as medidas da altura, do diâmetro das copas e do número de ramos. A determinação da biomassa de cada árvore foi obtida pelo método da proporcionalidade. Os modelos testados foram adaptados de Spurr e de Schumacher & Hall, para biomassa aérea e biomassa total (biomassa aérea mais biomassa de raízes pivotantes. O estoque de carbono foi estimado através da multiplicação da biomassa seca pelo teor de carbono da matéria seca, que foi obtido pelo método da calcinação em mufla. A estimativa do CO2 equivalente estocado foi obtida pela multiplicação do estoque de carbono pelo fator 44/12. A equação que obteve melhor ajuste e que foi utilizada para determinação do estoque de carbono deste estudo foi a de Spurr, com os dados de biomassa total, B=0,7601*(DC2*H0,8949, em que B = biomassa (kg; DC = diâmetro de copa (m; e H = altura (m. O estoque de carbono encontrado da cultura, no quarto ano, foi de 6,79MgC ha-1, correspondendo a 24,89Mg CO2(eq ha-1. Os resultados mostram que o pinhão-manso é ambientalmente viável para elaboração de projetos MDL de florestamento/reflorestamento ou em projetos de carbono para mercados voluntários, agregando renda ao produtor rural e melhorando a atratividade financeira da cultura.This study had the objectives to estimate equations of biomass and carbon stock of Jatropha (Jatrophacurcas L.. The area of this study is located in Viçosa, Minas Gerais, planting carried out in 3.5x3.0m spacing at 4.64ha. To biomass quantification, we used the direct destructive method, applied to trees, which were

O papel das franquias na reestruturação das cidades: a ascensão do setor em Viçosa – MG

Directory of Open Access Journals (Sweden)

Rodrigo Moraes Fritz

2017-12-01

Full Text Available No estágio atual do sistema capitalista no mundo, as estratégias dos agentes econômicos para sobreviverem no mercado se fazem cada vez mais notórias. Tida como uma modernização na forma de vender e comprar, o Franchising vem se destacando em todo mundo e sendo fator importante na economia dos países. As franquias são muito presentes em realidades urbanas complexas, como as metrópoles, porém, nos últimos anos, nota-se sua difusão para centros urbanos intermediários, particularmente em cidades consideradas como médias, que possuem certo grau de influência regional. A cidade de Viçosa, localizada na Zona da Mata mineira, faz parte desse conjunto de cidades que, pela centralidade que exercem, atraem capitais, pessoas e mercadorias. O crescente número de franquias na cidade em questão despertou o interesse em caracterizá-las e entendê-las do ponto de vista da sua espacialidade, bem como do potencial que apresentam para promover mudanças na estrutura urbana, já que elas são indutoras de investimentos, reestruturações e, principalmente, de centralidade.

Functional network macroscopes for probing past and present Earth system dynamics (Invited)

Science.gov (United States)

Donges, J. F.

2013-12-01

The Earth, as viewed from a physicist's perspective, is a dynamical system of great complexity. Functional complex networks are inferred from observational data and model runs or constructed on the basis of theoretical considerations. Representing statistical interdependencies or causal interactions between objects (e.g., Earth system subdomains, processes, or local field variables), functional complex networks are conceptually well-suited for naturally addressing some of the fundamental questions of Earth system analysis concerning, among others, major dynamical patterns, teleconnections, and feedback loops in the planetary machinery, as well as critical elements such as thresholds, bottlenecks, and switches. The first part of this talk concerns complex network theory and network-based time series analysis. Regarding complex network theory, the novel contributions include consistent frameworks for analyzing the topology of (i) general networks of interacting networks and (ii) networks with vertices of heterogeneously distributed weights, as well as (iii) an analytical theory for describing spatial networks. In the realm of time series analysis, (i) recurrence network analysis is put forward as a theoretically founded, nonlinear technique for the study of single, but possibly multivariate time series. (ii) Coupled climate networks are introduced as an exploratory tool of data analysis for quantitatively characterizing the intricate statistical interdependency structure within and between several fields of time series. The second part presents applications for detecting dynamical transitions (tipping points) in time series and studying bottlenecks in the atmosphere's general circulation structure. The analysis of paleoclimate data reveals a possible influence of large-scale shifts in Plio-Pleistocene African climate variability on events in human evolution. This presentation summarizes the contents of the dissertation titled "Functional network macroscopes for

Projeto Sabão Ecológico: uma estratégia educacional para a reciclagem do óleo de cozinha no município de Viçosa

OpenAIRE

Yaankha Bharbara Allecxandria Bernardo da Silva Barbosa Cardoso; Sabrina Marcelino Amoglia; Julie Louise McClelland; Amanda Ferreira Teixeira; Laura Fernandes Melo

2017-01-01

O descarte inadequado de resíduos de óleo de cozinha usado pode causar danos ambientais no local onde é descartado, bem como no entorno, fato que desrespeita um dos direitos do ser humano: o acesso ao ambiente ecologicamente equilibrado. Neste contexto, o Projeto Sabão Ecológico foi criado pela ONG Engenheiros Sem Fronteiras – Núcleo Viçosa, devido à necessidade de conscientizar a população sobre os danos inerentes ao descarte incorreto desse óleo. Por meio de oficinas teórico-práticas, que e...

Obstructive sleep apnoea is frequent in patients with type 1 diabetes

DEFF Research Database (Denmark)

Banghoej, Anne Margareta; Nerild, Henriette Holst; Kristensen, Peter Lommer

2017-01-01

mild OSA (60 patients (69%)). OSA was present in 32% of the patients with normal BMI, in 60% of overweight patients, and in 61% of obese patients. Patients with type 1 diabetes and OSA were largely asymptomatic and did not report more sleepiness than patients without OSA. At multivariate analysis, age......AIM: Obstructive Sleep Apnoea (OSA) is frequent in patients with type 2 diabetes. The aim of this study is to evaluate prevalence of OSA in patients with type 1 diabetes. METHODS: In a cross-sectional design, all patients with type 1 diabetes attending the outpatient clinic were offered screening...... of 200 of 518 eligible patients with type 1 diabetes (39%) participated (68% men; age 52±15years (mean±SD), diabetes duration 24±14years and BMI 25.3±3.3kg/m(2)). OSA was diagnosed in 92 patients (46% (95% CI: 40-53)). Five patients had known OSA, and OSA was newly diagnosed in 87 patients, predominantly...

Endothelial Dysfunction in Children With Obstructive Sleep Apnea Is Associated With Elevated Lipoprotein-Associated Phospholipase A2 Plasma Activity Levels.

Science.gov (United States)

Kheirandish-Gozal, Leila; Philby, Mona F; Qiao, Zhuanghong; Khalyfa, Abdelnaby; Gozal, David

2017-02-09

Obstructive sleep apnea (OSA) is a highly prevalent condition, especially in obese children, and has been associated with increased risk for endothelial dysfunction and dislipidemia, which are precursors of atherosclerosis. Lipoprotein-associated phospholipase A2 (Lp-PLA2) is recognized as an independent risk factor for cardiovascular risk and atheromatous plaque activity. We hypothesized that Lp-PLA2 levels would be elevated in children with OSA, particularly among obese children who also manifest evidence of endothelial dysfunction. One hundred sixty children (mean age 7.1±2.3 years), either nonobese with (n=40) and without OSA (n=40) or obese with (n=40) and without OSA (n=40) underwent overnight polysomnographic and postocclusive reperfusion evaluation and a fasting blood draw the morning after the sleep study. In addition to lipid profile, Lp-PLA2 plasma activity was assessed using a commercial kit. Obese children and OSA children had significantly elevated plasma Lp-PLA2 activity levels compared to controls. Furthermore, when both obesity and OSA were concurrently present or when endothelial function was present, Lp-PLA2 activity was higher. Treatment of OSA by adenotonsillectomy resulted in reductions of Lp-PLA2 activity (n=37; P <0.001). Lp-PLA2 plasma activity is increased in pediatric OSA and obesity, particularly when endothelial dysfunction is present, and exhibits decreases on OSA treatment. The short-term and long-term significance of these findings in relation to cardiovascular risk remain undefined. © 2017 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.

ITER JCT presentation at the International Conference on Fusion Reactor Materials (ICFRM-9)

International Nuclear Information System (INIS)

Kalinin, G.; Barabash, V.; Ioki, K.

1999-01-01

During this conference four invited papers and one poster paper were presented on behalf of the ITER Joint Central Team with the review of latest achievements. The results of the comprehensive materials R and D program in support of the ITER design were extensively reported the ITER Home Teams

Invited to a Beheading: A Real Individual in Search of Freedom

Directory of Open Access Journals (Sweden)

Bahare Jalali Farahani

2016-11-01

Full Text Available Among the most prominent political novels of the twentieth century, Invitation to a Beheading is the acme of Nabokov’s art in that it was embellished by the finest Nabokovian techniques, and was enriched by thought- provoking ideas. This study is aimed to offer a narratological reading of this novel in search of what its implied author has pictured as the meaning of genuine freedom intended by Nabokov. By analyzing the story and discourse levels of this narrative, we are going to discuss, first, the concepts of ‘reality’ and ‘individuality’ in Invitation to a Beheading as the pillars on which the author constructed the ultimate concept of freedom. After discussing the contribution of these two notions, in the last section of this article, dedicated to the questions of ideology and rhetoric, we place the ultimate concept of freedom in the period in which the novel was composed. We discuss how the final picture is in accordance with the peculiarities of the modern world that went through two World Wars and witnessed the outcome of totalitarian systems.

The “DOC” screen: Feasible and valid screening for depression, Obstructive Sleep Apnea (OSA) and cognitive impairment in stroke prevention clinics

Science.gov (United States)

Swartz, Richard H.; Cayley, Megan L.; Lanctôt, Krista L.; Murray, Brian J.; Cohen, Ashley; Thorpe, Kevin E.; Sicard, Michelle N.; Lien, Karen; Sahlas, Demetrios J.; Herrmann, Nathan

2017-01-01

Background Post-stroke Depression, Obstructive sleep apnea (OSA) and Cognitive impairment (“DOC”) are associated with greater mortality, worse recovery and poorer quality of life. Best practice recommendations endorse routine screening for each condition; yet, all are under-assessed, diagnosed and treated. We seek to determine the feasibility and validity of an integrated tool (“DOC” screen) to identify stroke clinic patients at high-risk of depression, OSA, and cognitive impairment. Methods All consecutive new referrals to a regional Stroke Prevention Clinic who were English-speaking and non-aphasic were eligible to be screened. Time for screen completion was logged. DOC screen results were compared to the neuropsychological battery and polysomnogram assessments using a modified receiver operator characteristic and area under the curve analysis. Data is reported to conform to STARD guidelines. Findings 1503 people were screened over 2 years. 89% of eligible patients completed the screen in 5 minutes or less (mean 4.2 minutes), less than half the time it takes to complete the Montreal Cognitive Assessment (MoCA). 437 people consented to detailed testing. Of those, 421 completed the Structured Clinical Interview for Depression within 3 months of screening, 387 completed detailed neuropsychological testing within 3 months, and 88 had overnight polysomnograms. Screening scores combined with demographic variables (age, sex, education, body mass index), had excellent validity compared to gold standard diagnoses: DOC-Mood AUC 0.90; DOC-Apnea AUC 0.80; DOC-Cog AUC 0.81. DOC screen scores can reliably categorize patients in to low-, intermediate- or high-risk groups for further action and can do so with comparable accuracy to more time-consuming screens. Conclusions Systematic screening of depression, obstructive sleep apnea, and cognitive impairment in 5 minutes or less is feasible and valid in a high volume stroke clinic using the DOC screen. The DOC screen may

CinéGlobe invites you to participate in a poster design competition

CERN Multimedia

Neal David Hartman

2013-01-01

For its 2014 publicity campaign, CinéGlobe invites CERN people to participate in a poster design competition.  The entries are now on display on the Pas Perdus in the main building, and the CERNois are invited to vote for their favourites.    CinéGlobe is the international festival of short films inspired by science that takes place every two years at CERN, in the Globe of Science and Innovation. From 18 to 23 March 2014, CERN will host the fourth edition of the festival. The mission of the CinéGlobe Film Festival is to challenge the commonly perceived divisions between science and art by demonstrating that they are both essential to interpreting our world. Open to short film creators from around the world, the CinéGlobe festival is truly international, the first three editions having attracted more than 4,000 entries from more than 100 countries around the globe.  In addition to screening...

Invitations and excuses that are not invitations and excuses: Gossip in Luke 14:18–20

Directory of Open Access Journals (Sweden)

Ernest van Eck

2012-08-01

Full Text Available In modern Western culture, gossip is seen as a malicious activity that should be avoided. In ancient oral-cultures, gossip as a cultural form did not have this negative connotation. Gossip was a necessary social game that enabled the flow of information. This information was used in the gossip network of communities to clarify, maintain and enforce group values, facilitate group formation and boundary maintenance and assess the morality of individuals. Gossip was a natural and spontaneous recurring form of social organisation. This understanding of gossip is used to interpret the two invitations and three excuses in the parable of the Feast (Lk 14:16a–23. The conclusion reached is that gossip, when understood as a social game, can be a useful tool to curb anachronistic and ethnocentristic readings of texts produced by cultures different from that of modern interpreters analysing these texts.

Evolución de la propiedad, la tecnología y la sostenibilidad en la región montañosa de Nariño.

Directory of Open Access Journals (Sweden)

Irma Baquero

2010-05-01

Full Text Available Se analiza el efecto de las instituciones en las decisiones de conservación de recursos naturales de los productores agropecuarios en la región montañosa de Nariño. El análisis se basa en las características del sistema de propiedad: derecho de exclusión, seguridad y capacidad de ser transado. A pesar de que la teoría considera a la propiedad privada como la que mayores incentivos genera para la conservación, los resultados del análisis demuestran que esto no siempre es cierto y que otros factores, como los demográficos y tecnológicos, fueron determinantes de las decisiones.

Invited Colloquium on Negotiating the Complexities of Multilingual Assessment, AAAL Conference 2014

Science.gov (United States)

Menken, Kate; Shohamy, Elana

2015-01-01

The invited colloquium on New Directions in Language Assessment held at the American Association for Applied Linguistics (AAAL) annual meeting in Portland, Oregon on March 22, 2014 brought together an international panel of scholars to together explore the possibilities and challenges of translanguaging and bi/multilingual approaches in…

76 FR 66698 - Postsecondary Educational Institutions Invited To Participate in Experiments Under the...

Science.gov (United States)

2011-10-27

... typically need their student aid funds early to meet obligations for travel to the site of their upcoming... Education. ACTION: Notice. Overview Information: Federal Student Financial Assistance Programs under Title... invites postsecondary educational institutions (institutions) that participate in the student assistance...

Epidemiological survey of the taeniasis/cysticercosis complex in cattle farms in Viçosa County, Minas Gerais, Brazil Inquérito epidemiológico sobre o complexo teníase-cisticercose bovina no município de Viçosa, Minas Gerais

Directory of Open Access Journals (Sweden)

Tatiane O. Santos

2013-04-01

Full Text Available Despite the importance of human taeniasis/bovine cysticercosis for public and animal health and the economy, its actual epidemiological status in Brazil is not well-studied. We sought to assess the epidemiological profile of this zoonosis in the rural area of Viçosa County, Minas Gerais, Brazil. The prevalence of bovine cysticercosis was 0.42%, whereas no case of human taeniasis was diagnosed. Factors favoring the persistence of zoonosis were identified. These included the supply of untreated water to animals, animals raised for slaughter without sanitary supervision, poor mechanization of raising techniques, and the use of untreated water for human consumption. Bovine meat for human consumption acquired in the city or from the farm itself was characterized as a risk factor for bovine cysticercosis (Odds Ratio (OR =16.77; pApesar da importância do complexo teníase-cisticercose bovina para a saúde pública, animal e para a economia, a realidade epidemiológica da ocorrência dessas zoonoses no Brasil é pouco conhecida. Este estudo foi realizado com o objetivo de avaliar o perfil epidemiológico desta zoonose na zona rural do município de Viçosa, MG. A prevalência encontrada de cisticercose bovina foi de 0,42%, e nenhum caso de teníase humana foi diagnosticado. Foi verificada presença de fatores favoráveis a manutenção dessa zoonose, como fornecimento de água sem tratar aos animais, criação de animais destinados ao abate sem inspeção sanitária, criação de bovinos com baixa adoção de tecnologia, e utilização de água sem tratamento. O consumo de carne bovina oriunda da propriedade e da cidade foi caracterizado como variável de risco (OR=16,77; p<0,05 para a cisticercose bovina. Apesar disso, as famílias das propriedades pesquisadas possuíam hábitos favoráveis como medida de controle para o desenvolvimento desta parasitose, como a quase ausência de esgoto a céu aberto e a ingestão de carne bovina bem passada. A

Composição florística de dois trechos em diferentes etapas serais de uma floresta estacional semidecidual em Viçosa, Minas Gerais Floristic composition of two sites different seral stages of semideciduous seasonal montane forest in Viçosa, Minas Gerais

Directory of Open Access Journals (Sweden)

Rogério Ferreira Ribas

2003-12-01

Full Text Available O presente estudo foi desenvolvido em dois trechos de floresta semidecídua, com diferentes estádios de sucessão secundária, localizada no município de Viçosa-MG, objetivando verificar variações qualitativas na composição florística. Foram demarcadas, em cada trecho, dez parcelas de 10 x 20 m, nas quais foram inventariados todos os indivíduos lenhosos com circunferência à altura de 130 cm do solo maior ou igual a 5 cm. A similaridade florística entre as parcelas foi avaliada por meio de análise de agrupamentos, utilizando o índice de Sørensen. Foram amostradas 67 espécies no trecho com 15 anos e 69 no trecho com 30 anos. Dentre as espécies exclusivas, 38 foram para o trecho com 15 anos e 40 para o trecho com 30 anos. As famílias Annonaceae, Leguminosae Caesalpinioideae e Sapindaceae, com cinco, quatro e quatro espécies cada, respectivamente, e o gênero Nectandra, com duas espécies, foram os taxa mais bem representados no trecho com 15 anos. Por outro lado, as famílias Flacourtiaceae, Meliaceae e Myrtaceae, com quatro, três e quatro espécies, respectivamente, e o gênero Ocotea, com três espécies, foram mais bem representados no trecho com 30 anos. A similaridade florística entre parcelas de um mesmo trecho foi considerada alta, tendo sido relacionada à proximidade espacial, o que implica históricos de perturbação e regeneração semelhantes, resultando, conseqüentemente, em composições florísticas mais similares e mesmo estádio de sucessão secundária.This study was carried out in two sites of a semideciduous forest, under different stages of secondary succession in Viçosa, MG to verify qualitative variations in floristic composition. In each site, ten plots of 10 m x 20 m were delimited, with all woody individuals with circumference at 130 cm height from the soil larger than or equal to 5 cm being listed. Floristic similarity among parcels was evaluated through clustering analysis, using the S�

Epidemiological survey of the taeniasis/cysticercosis complex in cattle farms in Viçosa County, Minas Gerais, Brazil

Directory of Open Access Journals (Sweden)

Tatiane O. Santos

2013-04-01

Full Text Available Despite the importance of human taeniasis/bovine cysticercosis for public and animal health and the economy, its actual epidemiological status in Brazil is not well-studied. We sought to assess the epidemiological profile of this zoonosis in the rural area of Viçosa County, Minas Gerais, Brazil. The prevalence of bovine cysticercosis was 0.42%, whereas no case of human taeniasis was diagnosed. Factors favoring the persistence of zoonosis were identified. These included the supply of untreated water to animals, animals raised for slaughter without sanitary supervision, poor mechanization of raising techniques, and the use of untreated water for human consumption. Bovine meat for human consumption acquired in the city or from the farm itself was characterized as a risk factor for bovine cysticercosis (Odds Ratio (OR =16.77; p<0.05. Nevertheless, the families on the investigated farms did apply several appropriate measures to control this disease, such as the virtual lack of open sewers and the consumption of well-cooked meat. The presence of bovine cysticercosis cases, and the factors favoring its persistence, point to the need for constant epidemiological and sanitary surveillance in this county.

Vulnerabilidad por aprovechamiento y distribución de especies leñosas desde la perspectiva comunitaria en la reserva cañón del Usumacinta, Tabasco, México

Directory of Open Access Journals (Sweden)

Samuel Cabrera-Pérez

2015-08-01

Full Text Available El objetivo de la investigación fue docu-mentar los usos y grado de vulnerabilidad de la flora leñosa multiuso, usando para ello la perspectiva de los pobladores, así como describir la distribución en los ambientes de estas especies sobre el territorio que ocupa la comunidad de Niños Héroes, Tenosique, Tabasco, México. Se emplearon métodos etnobotánicos tales como: recorridos de campo con conocedores de la flora del sitio, colecta botánica y aplicación de entrevistas en cada vivienda de la comunidad. Estas últimas, incluyeron preguntas generales y específicas para documentar los usos y pedir colaboración para la realización de un taller comunitario para fundamentar la construcción del índice vulnerabilidad por aprovechamiento de la flora leñosa. Se identificaron 168 especies de flora leñosa útil, de las cuales 97 son multiusos. Éstas se agruparon en 20 categorías de utilidad, entre las que destaca la leña con 71 especies, seguidas por materiales para instrumentos de trabajo de campo (65, materiales para la construcción de casas rurales (63, cerco muerto (53, comestible (53, y cerco vivo (50. La selva y el acahual son los hábitats con mayor número de especies de flora multiusos y proveen al colectivo 27 y 26% del total respectivamente. El 22% de las especies multiusos presentan alta vulnerabilidad de aprovechamiento, mientras que 50% están categorizadas con vulnerabilidad baja por aprovechamiento. El índice aquí evaluado, permite detectar el grado de vulnerabilidad al aprovechamiento de manera local o regional, pero no se corresponde a los índices de amenaza establecidos por la Norma Oficial Mexicana NOM-059-SEMARNAT de protección ambiental de especies nativas de México. Este índice permite poner alertas a nivel local o regional con relación a la fragilidad de las especies. La información generada, sienta bases para el manejo de los recursos y puede servir de guía para las agencias del gobierno, instituciones

Intermittent hypoxia simulating obstructive sleep apnea causes pulmonary inflammation and activates the Nrf2/HO-1 pathway.

Science.gov (United States)

Wang, Yeying; Chai, Yanling; He, Xiaojie; Ai, Li; Sun, Xia; Huang, Yiling; Li, Yongxia

2017-10-01

Obstructive sleep apnea (OSA) is a disorder with high morbidity in adults. OSA damages multiple organs and tissues, including the cardiovascular and cerebrovascular systems, the metabolism system, the lungs, liver and heart. OSA-induced damage is earliest and greatest to the pulmonary tissue. The present study established a rat OSA model of differing severity by inducing intermittent hypoxia with different concentrations of O 2 and it was determined that OSA caused a severe oxidative stress response and pulmonary inflammation in a dose-dependent manner. OSA increased serum levels of C-reactive protein and 8-isoprostane and elevated the expression of malondialdehyde, tumor necrosis factor α, interleukin (IL)-1β and IL-6 in the pulmonary tissue. Furthermore, the expression of two important antioxidants, superoxide dismutase and glutathione, was downregulated following intermittent hypoxia. By contrast, levels of cylooxygenase 2 and inducible nitric oxide synthase, which are crucial in the antioxidative response, increased. In addition, OSA activates the nuclear factor erythroid 2-related factor 2 (Nrf2)/heme oxygenase (OH)-1 antioxidative signaling pathway. Finally, all increases and decreases in levels of inflammatory and antioxidative substances were dependent on oxygen concentrations. Therefore, the present study demonstrated that OSA, simulated by intermittent hypoxia, caused an oxidative stress response and pulmonary inflammation, and activated the canonical antioxidative Nrf2/HO-1 signaling pathway in a dose-dependent manner. These results may facilitate the development of clinical therapies to treat pulmonary diseases caused by OSA.

Director general presentation to personnel

CERN Multimedia

2016-01-01

Dear Colleagues, Many important discussions are scheduled for the upcoming Council Week (13-17 June) on topics including the Medium-Term Plan, the Pension Fund and other matters of great relevance to us.   I would therefore like to share the main outcome of the week with you and I invite you to join me and the Directors in the Main Auditorium at 10 a.m. on Thursday 23 June. The meeting will last about one hour and a webcast will also be available. Best regards, Fabiola Gianotti DG presentation to personnel Thursday 23 June at 10 am Main Auditorium Retransmission in Council Chamber, IT Auditorium, Kjell Jonhsen Auditorium, Prevessin 864-1-C02 Webcast on cern.ch/webcast More information on the event page.

Análise hidrológica e socioambiental da bacia hidrográfica do córrego Romão dos Reis, Viçosa-MG The hydrographic watershed of Romão dos Reis stream, Viçosa-MG

Directory of Open Access Journals (Sweden)

Genice Vieira Santos

2007-10-01

Full Text Available O objetivo deste trabalho foi analisar os aspectos hidrológico e socioeconômico da bacia hidrográfica do córrego Romão dos Reis, que se localiza no Município de Viçosa, na região da Zona da Mata do Estado de Minas Gerais. O estudo enfatizou o uso e ocupação da terra como fatores determinantes na análise da qualidade da água, além dos fatores físicos da bacia. Esta foi dividida em sub-bacias, o que possibilitou a escolha de locais representativos para coleta e análise de dados. Coletaram-se os dados referentes a vazão, qualidade da água, elevações, precipitação, uso do solo, tipo de solo e aspectos sociais e econômicos. Para a elaboração dos mapas, utilizou-se o modelo digitalizado, construído a partir de mosaicos e fotos aéreas da região, na escala de 1:30.000. As informações sobre o número de moradores e proprietários, assim como os seus respectivos sistemas de cultivos e ocupação na bacia, foram obtidas por meio de entrevistas semi-estruturadas, visando melhor compreender a organização social e o manejo de uso da terra das propriedades. Foram apontados indicadores de degradação, assim como estratégias de manejo adequadas à melhoria ambiental, que venham contribuir e garantir a sustentabilidade da bacia.This study was carried out to analyze the hydrological and socioeconomic aspects in the hydrographic watershed of Romão dos Reis stream in Viçosa county, Zona da Mata region, Minas Gerais State. In this study, the land use and occupation are emphasized as determinant factors for analyzing water quality, besides physical factors. The watershed was divided into sub-watersheds enabling to choose the representative sites for data collection and analysis. Data on flow rate, water quality, relief, precipitation, landscape (top, hillside and terrace, soil type, social and economic aspects were collected. A digitalized model built from mosaics and aerial photos of the area at 1:30.000 scale was used to draw up

Obstructive sleep apnea and cancer: effects of intermittent hypoxia?

Science.gov (United States)

Kukwa, Wojciech; Migacz, Ewa; Druc, Karolina; Grzesiuk, Elzbieta; Czarnecka, Anna M

2015-01-01

Obstructive sleep apnea (OSA) is a common disorder characterized by pauses in regular breathing. Apneic episodes lead to recurrent hypoxemia-reoxygenation cycles with concomitant cellular intermittent hypoxia. Studies suggest that intermittent hypoxia in OSA may influence tumorigenesis. This review presents recent articles on the potential role of OSA in cancer development. Relevant research has focused on: molecular pathways mediating the influence of intermittent hypoxia on tumor physiology, animal and epidemiological human studies linking OSA and cancer. Current data relating OSA to risk of neoplastic disease remain scarce, but recent studies reveal the potential for a strong relation. More work is, therefore, needed on the impact of OSA on many cancer-related aspects. Results may offer enlightenment for improved cancer diagnosis and treatment.

"Silent" Sleep Apnea in Dentofacial Deformities and Prevalence of Daytime Sleepiness After Orthognathic and Intranasal Surgery.

Science.gov (United States)

Posnick, Jeffrey C; Adachie, Anayo; Singh, Neeru; Choi, Elbert

2018-04-01

The purposes of this study were to determine the occurrence of undiagnosed "silent" obstructive sleep apnea (OSA) in dentofacial deformity (DFD) patients at initial surgical presentation and to report on the level of daytime sleepiness in DFD patients with OSA and chronic obstructive nasal breathing (CONB) after undergoing bimaxillary, chin, and intranasal surgery. A retrospective cohort study of patients with a bimaxillary DFD and CONB was implemented. Patients were divided into those with no OSA (group I) and those with OSA (group II). Group II was further subdivided into patients referred with polysomnogram (PSG)-confirmed OSA (group IIa) and those with a diagnosis of OSA only after surgical consultation, airway evaluation, and a positive PSG (group IIb). Group II patients were analyzed at a minimum of 1 year after surgery (range, 1 to 10 years) for daytime sleepiness with the Epworth Sleepiness Scale. Patients with postoperative excessive daytime sleepiness were assessed for risk factors and continued need for OSA treatment. Patients in group II were studied to determine which DFD patterns were most associated with OSA. We compared the prevalence of OSA between our study population and the general population. Two hundred sixty-two patients met the inclusion criteria. Of these, 23% (60 of 262) had PSG-confirmed OSA (group II). This rate was much higher than that found in the general population. Of the patients, 7% (19 of 262) were known to have OSA at initial surgical consultation (group IIa). An additional 16% (41 of 262) were later confirmed by PSG to have OSA (group IIb). Patients with primary mandibular deficiency and short face DFDs were most likely to have OSA (P surgery. A significant association was found between group II patients with postoperative excessive daytime sleepiness ("sleepy" or "very sleepy") and a preoperative body mass index category of overweight (P = .026). Our study found silent OSA to be frequent in the DFD population. The

Department of Energy's regional solar updates 1979. Volume two. Invited papers and appendices

Energy Technology Data Exchange (ETDEWEB)

None

1979-01-01

Twenty-six invited papers for the regional meetings at Dearborn, Michigan; Orlando, Florida; Philadelphia, Pennsylvania; and Los Angeles, California are included. Separate abstracts were prepared for each paper. (MHR)

Effect of CPAP-therapy on bronchial and nasal inflammation in patients affected by obstructive sleep apnea syndrome.

Science.gov (United States)

Lacedonia, D; Salerno, F G; Carpagnano, G E; Sabato, R; Depalo, A; Foschino-Barbaro, M P

2011-06-01

Obstructive sleep apnea syndrome (OSAS) has been shown to be associated to upper and lower airways inflammation. Continuous positive airway pressure (CPAP) is the elective treatment of OSAS. The aim of the present study was to assess the effect of CPAP-therapy on airway and nasal inflammation. In 13 non-smoking subjects affected by untreated OSAS and in 11 non-smoking normal volunteers, airway inflammation was detected by analyses of the induced sputum. In the OSAS group measurements were repeated after 1, 10 and 60 days of the appropriate CPAP treatment. In addition, in 12 subjects of the OSAS group, nasal inflammation was detected by the analysis of induced nasal secretions at baseline, and after 1, 10 and 60 days of CPAP treatment. OSAS patients, compared to normal controls, showed at baseline a higher percentage of neutrophils and a lower percentage of macrophages in the induced sputum. One, 10 and 60 days of appropriate CPAP-therapy did not change the cellular profile of the induced sputum. In addition, in the OSAS patients, the high neutrophilic nasal inflammation present under baseline conditions was not significantly modified by CPAP-therapy. Finally, no patients developed airway hyper-responsiveness after CPAP therapy. In OSAS subjects, the appropriate CPAP-therapy, while correcting the oxygen desaturation, does not modify the bronchial and nasal inflammatory profile.

Sleep apnea in patients reporting insomnia or restless legs symptoms.

Science.gov (United States)

Bianchi, M T; Goparaju, B; Moro, M

2016-01-01

Insomnia and restless legs syndrome (RLS) are defined by self-reported symptoms, and polysomnography (PSG) is not routinely indicated. Occult obstructive sleep apnea (OSA), common even in asymptomatic adults, may complicate management of patients presenting with insomnia or restless legs. To this end, we investigated objective sleep apnea metrics in a large retrospective cohort according to self-reported symptom profiles. We compared sleep apnea findings in patients referred to our center according to self-reported symptoms associated with insomnia, sleep apnea, and restless legs. The cohort included over 1900 adults who underwent diagnostic (n = 1418) or split-night (n = 504) PSGs and completed a symptom and medical history questionnaire. More than 30% of patients who did not endorse any OSA symptoms, but did endorse insomnia or restless legs symptoms, were found to have OSA based on apnea-hypopnea index (AHI) >5 during overnight laboratory testing. Regression models of the full cohort showed that the risk of OSA was related, as expected, to older age, male sex, elevated body mass index, and presence of OSA symptoms. The presence of insomnia symptoms did not alter the risk of OSA. The presence of restless legs symptoms showed a small odds ratio for lowered OSA risk. Objective evidence of OSA occurs similarly in those with insomnia or restless legs symptoms, even among those without self-reported OSA symptoms. Providers should be aware of the potential for occult OSA in populations with insomnia and restless legs, which may complicate their management in addition to presenting an independent medical risk itself. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Tendências recentes nos elementos do clima e suas implicações na evapotranspiração da cultura do milho em Viçosa - MG Recent trends in the weather elements and its implications in the maize crop evapotranspiration in Viçosa-MG, Brazil

Directory of Open Access Journals (Sweden)

Leonidas P. de Alencar

2011-01-01

Full Text Available A mudança nas condições climáticas tem gerado grandes preocupações em nível mundial, sendo que uma das grandes questões, neste contexto, é o aquecimento global. As alterações ocorridas nas condições climáticas podem afetar a demanda de água das plantas, porque a evapotranspiração é afetada por mudanças nos elementos climáticos. O objetivo deste trabalho foi analisar os efeitos das possíveis mudanças dos elementos do clima na evapotranspiração de referência e na evapotranspiração da cultura do milho para a região de Viçosa - MG. Mediante análise de tendência pelo teste de Mann-Kendall e da estatística do teste t da regressão linear, verificou-se o comportamento dos seguintes elementos climáticos: temperaturas máxima e mínima, insolação, velocidade do vento e umidade relativa. Observou-se uma redução na evapotranspiração de referência e da cultura do milho ao longo dos últimos 41 anos, principalmente em razão da redução da insolação e da velocidade do vento. A evapotranspiração de referência apresentou redução da ordem de 4,2 mm por ano.The change in weather conditions has caused great concern in the world and the major issue, in this context, is the global warming. The changes in climate may affect the water demand of plants, because the evapotranspiration is affected by changes in climatic elements. The objective of this study was to examine the possible effects of climatological changes in evapotranspiration and reference evapotranspiration of corn in Viçosa - MG, Brazil. Trend analysis by the Mann-Kendall statistic and student t test of the linear regression were used to study the behavior of the following weather elements: maximum and minimum temperatures, sunshine duration, wind speed and relative humidity. It was observed a reduction in the reference evapotranspiration and maize crop evapotranspiration over the recent past 41 years, mainly because of reduced solar radiation and wind

Association between mothers' screening uptake and daughters' HPV vaccination: a quasi-experimental study on the effect of an active invitation campaign.

Science.gov (United States)

Venturelli, Francesco; Baldacchini, Flavia; Campari, Cinzia; Perilli, Cinzia; Pascucci, Maria Grazia; Finarelli, Alba Carola; Moscara, Luigi; Rossi, Paolo Giorgi

2017-09-25

In Emilia-Romagna, the Human Papillomavirus (HPV) vaccination campaign started in 2008 offering free vaccines for 1996 and 1997 cohorts. Systematic active invitation was implemented for the 1997 cohort. Our study aimed at measuring the impact of the active invitation campaign on HPV vaccine coverage and on coverage inequalities in 11-year-old girls. Second, we evaluated the effect of the HPV vaccination campaign on participation in cervical cancer screening by mothers of target girls. We collected information on vaccination status for girls residing in Reggio Emilia in 2008 and mothers' screening history, before and after the 2008 vaccination campaign. Log-binomial regression models were performed to estimate Relative Risk (RR) and 95% confidence intervals (CIs) of being vaccinated as regarded citizenship, siblings, mothers' education, marital status and screening history, stratified by birth cohort. We also calculated RR of receiving a Pap test after the vaccination campaign as regarded education, daughter's cohort and mothers' decision to have their daughter vaccinated. Interaction between education and cohort in mothers overdue for Pap testing was calculated. Vaccination coverage was 46.3% for the uninvited cohort (1046/2260) and 77.9% for the invited cohort (1798/2307). In the uninvited cohort, daughters' vaccination showed association with mothers' education (8 to 11 years of education vs. graduated mothers, RR 1.61 95% CI 1.14-2.28), citizenship (foreigners vs. Italians, RR 0.45 95% CI 0.37-0.56) and screening history (regular vs. non-participant; RR 1.72 95% CI 1.26-2.36). In the invited cohort, only a slight association with screening history persisted (regular vs. non-participant; RR 1.20 95% CI 1.04-1.40). Highly educated under-screened mothers of the invited cohort showed a higher probability of receiving a Pap test after the vaccination campaign period (RR 1.27 95% CI 1.04-1.56) compared with those not invited, CONCLUSION: Active invitation

Association between mothers’ screening uptake and daughters’ HPV vaccination: a quasi-experimental study on the effect of an active invitation campaign

Science.gov (United States)

Baldacchini, Flavia; Campari, Cinzia; Perilli, Cinzia; Pascucci, Maria Grazia; Finarelli, Alba Carola; Moscara, Luigi; Rossi, Paolo Giorgi

2017-01-01

Objectives In Emilia-Romagna, the Human Papillomavirus (HPV) vaccination campaign started in 2008 offering free vaccines for 1996 and 1997 cohorts. Systematic active invitation was implemented for the 1997 cohort. Our study aimed at measuring the impact of the active invitation campaign on HPV vaccine coverage and on coverage inequalities in 11-year-old girls. Second, we evaluated the effect of the HPV vaccination campaign on participation in cervical cancer screening by mothers of target girls. Methods We collected information on vaccination status for girls residing in Reggio Emilia in 2008 and mothers’ screening history, before and after the 2008 vaccination campaign. Log-binomial regression models were performed to estimate Relative Risk (RR) and 95% confidence intervals (CIs) of being vaccinated as regarded citizenship, siblings, mothers’ education, marital status and screening history, stratified by birth cohort. We also calculated RR of receiving a Pap test after the vaccination campaign as regarded education, daughter’s cohort and mothers’ decision to have their daughter vaccinated. Interaction between education and cohort in mothers overdue for Pap testing was calculated. Results Vaccination coverage was 46.3% for the uninvited cohort (1046/2260) and 77.9% for the invited cohort (1798/2307). In the uninvited cohort, daughters’ vaccination showed association with mothers’ education (8 to 11 years of education vs. graduated mothers, RR 1.61 95% CI 1.14–2.28), citizenship (foreigners vs. Italians, RR 0.45 95% CI 0.37–0.56) and screening history (regular vs. non-participant; RR 1.72 95% CI 1.26–2.36). In the invited cohort, only a slight association with screening history persisted (regular vs. non-participant; RR 1.20 95% CI 1.04–1.40). Highly educated under-screened mothers of the invited cohort showed a higher probability of receiving a Pap test after the vaccination campaign period (RR 1.27 95% CI 1.04–1.56) compared with

Specialist nurses’ perceptions of inviting patients to participate in clinical research studies: a qualitative descriptive study of barriers and facilitators

Directory of Open Access Journals (Sweden)

Caroline French

2016-08-01

Full Text Available Abstract Background Increasing the number of patients participating in research studies is a current priority in the National Health Service (NHS in the United Kingdom. The role of specialist nurses in inviting patients to participate is important, yet little is known about their experiences of doing so. The aim of this study was to explore the perceptions of barriers and facilitators held by specialist nurses with experience of inviting adult NHS patients to a wide variety of research studies. Methods A cross-sectional qualitative descriptive study was conducted between March and July 2015. Participants were 12 specialist nurses representing 7 different clinical specialties and 7 different NHS Trusts. We collected data using individual semi-structured interviews, and analysed transcripts using the Framework method to inductively gain a descriptive overview of barriers and facilitators. Results Barriers and facilitators were complex and interdependent. Perceptions varied among individuals, however barriers and facilitators centred on five main themes: i assessing patient suitability, ii teamwork, iii valuing research, iv the invitation process and v understanding the study. Facilitators to inviting patients to participate in research often stemmed from specialist nurses’ attitudes, skills and experience. Positive research cultures, effective teamwork and strong relationships between research and clinical teams at the local clinical team level were similarly important. Barriers were reported when specialist nurses felt they were providing patients with insufficient information during the invitation process, and when specialist nurses felt they did not understand studies to their satisfaction. Conclusion Our study offers several new insights regarding the role of specialist nurses in recruiting patients for research. It shows that strong local research culture and teamwork overcome some wider organisational and workload barriers reported in

Specialist nurses' perceptions of inviting patients to participate in clinical research studies: a qualitative descriptive study of barriers and facilitators.

Science.gov (United States)

French, Caroline; Stavropoulou, Charitini

2016-08-11

Increasing the number of patients participating in research studies is a current priority in the National Health Service (NHS) in the United Kingdom. The role of specialist nurses in inviting patients to participate is important, yet little is known about their experiences of doing so. The aim of this study was to explore the perceptions of barriers and facilitators held by specialist nurses with experience of inviting adult NHS patients to a wide variety of research studies. A cross-sectional qualitative descriptive study was conducted between March and July 2015. Participants were 12 specialist nurses representing 7 different clinical specialties and 7 different NHS Trusts. We collected data using individual semi-structured interviews, and analysed transcripts using the Framework method to inductively gain a descriptive overview of barriers and facilitators. Barriers and facilitators were complex and interdependent. Perceptions varied among individuals, however barriers and facilitators centred on five main themes: i) assessing patient suitability, ii) teamwork, iii) valuing research, iv) the invitation process and v) understanding the study. Facilitators to inviting patients to participate in research often stemmed from specialist nurses' attitudes, skills and experience. Positive research cultures, effective teamwork and strong relationships between research and clinical teams at the local clinical team level were similarly important. Barriers were reported when specialist nurses felt they were providing patients with insufficient information during the invitation process, and when specialist nurses felt they did not understand studies to their satisfaction. Our study offers several new insights regarding the role of specialist nurses in recruiting patients for research. It shows that strong local research culture and teamwork overcome some wider organisational and workload barriers reported in previous studies. In addition, and in contrast to common practice

The why, when and how to test for obstructive sleep apnea in patients with atrial fibrillation.

Science.gov (United States)

Desteghe, Lien; Hendriks, Jeroen M L; McEvoy, R Doug; Chai-Coetzer, Ching Li; Dendale, Paul; Sanders, Prashanthan; Heidbuchel, Hein; Linz, Dominik

2018-04-12

Sleep apnea is associated with increased cardiovascular risk and may be important in atrial fibrillation (AF) management. It is present in up to 62% of the AF population and is highly under-recognized and underdiagnosed. Obstructive sleep apnea (OSA) is strongly associated with AF and non-randomized trials have shown that its treatment can help to reduce AF recurrences and maintain sinus rhythm. The 2016 European Society of Cardiology guidelines for the management of AF recommend that AF patients should be questioned regarding the symptoms of OSA and that OSA-treatment should be optimized to improve AF treatment results. However, strategies on how to implement OSA testing in the standard work-up of AF patients are not provided in the guidelines. Additionally, overnight OSA monitoring rather than interrogation for OSA-related clinical signs alone may be necessary to reliably identify OSA in the majority of AF patients. This review summarizes the available clinical data on OSA in AF patients, and discusses the following key questions: Why and When is testing for OSA needed in AF patients? How and Where should it be performed and coordinated? and Who should test for OSA? To implement OSA testing in a cardiology or electrophysiology clinic, we propose a multidisciplinary integrated care approach based on a chronic care model. We describe the tools, infrastructure and coordination needed to test for OSA in the standard workup of patients with symptomatic AF prior to the initiation of directed invasive or pharmacological rhythm control management.

Presentation

Directory of Open Access Journals (Sweden)

Eduardo Vicente

2013-06-01

Full Text Available In the present edition of Significação – Scientific Journal for Audiovisual Culture and in the others to follow something new is brought: the presence of thematic dossiers which are to be organized by invited scholars. The appointed subject for the very first one of them was Radio and the invited scholar, Eduardo Vicente, professor at the Graduate Course in Audiovisual and at the Postgraduate Program in Audiovisual Media and Processes of the School of Communication and Arts of the University of São Paulo (ECA-USP. Entitled Radio Beyond Borders the dossier gathers six articles and the intention of reuniting works on the perspectives of usage of such media as much as on the new possibilities of aesthetical experimenting being build up for it, especially considering the new digital technologies and technological convergences. It also intends to present works with original theoretical approach and original reflections able to reset the way we look at what is today already a centennial media. Having broadened the meaning of “beyond borders”, four foreign authors were invited to join the dossier. This is the first time they are being published in this country and so, in all cases, the articles where either written or translated into Portuguese.The dossier begins with “Radio is dead…Long live to the sound”, which is the transcription of a thought provoking lecture given by Armand Balsebre (Autonomous University of Barcelona – one of the most influential authors in the world on the Radio study field. It addresses the challenges such media is to face so that it can become “a new sound media, in the context of a new soundscape or sound-sphere, for the new listeners”. Andrew Dubber (Birmingham City University regarding the challenges posed by a Digital Era argues for a theoretical approach in radio studies which can consider a Media Ecology. The author understands the form and discourse of radio as a negotiation of affordances and

Youth Voices on Global Citizenship: Deliberating across Canada in an Online Invited Space

Science.gov (United States)

Shultz, Lynette; Pashby, Karen; Godwaldt, Terry

2017-01-01

This article examines the processes of youth engagement in an "invited space" for Canadian secondary school students. The organizers created a participatory citizenship education space in which Canadian students discussed their views and visions and developed their policy position on global citizenship and global citizenship education.…

Strabismus and discrimination in children: are children with strabismus invited to fewer birthday parties?

Science.gov (United States)

Mojon-Azzi, Stefania Margherita; Kunz, Andrea; Mojon, Daniel Stéphane

2011-04-01

To determine the social acceptance of children with strabismus by their peers and to determine the age at which the negative impact of strabismus on psychosocial interactions emerges. Photographs of six children were digitally altered in order to create pictures of identical twins except for the position of the eyes (orthotropic, exotropic and exotropic) and the colour of the shirt. One hundred and eighteen children aged 3-12 years were asked to select, for each of the six twin pairs, one of the twins to invite to their birthday party. The grouping of the pictures and the composition of the twin pairs were determined by Latin squares. Children younger than 6 years old did not make any significant distinctions between orthotropic children and children with strabismus. Respondents aged 6 years or older invited children with a squint to their birthday parties significantly less often than orthotropic children. The authors found no impact (p>0.1) of gender, of the colour of the shirt or of the type of strabismus, but did find a highly significant impact of age on the number of invited children with strabismus. Children aged 6 years or older with a visible squint seem to be less likely to be accepted by their peers. Because this negative attitude towards strabismus appears to emerge at approximately the age of 6 years, corrective surgery for strabismus without prospects for binocular vision should be performed before this age.

Education as Invitation to Speak: On the Teacher Who Does Not Speak

Science.gov (United States)

Vansieleghem, Nancy; Masschelein, Jan

2012-01-01

As a response to "Le Fils," a film directed by the Dardenne brothers, we explore the idea of speaking as an invitation and juxtapose it against ideas of speaking as a transactional, calculative, calibrated, activity. Speaking tends to be understood as a relatively straightforward matter: as a means of communication structured by such values as the…

Integração na criação de frangos de corte na microrregião de Viçosa - MG: viabilidade econômica e análise de risco

Directory of Open Access Journals (Sweden)

Adelson Martins Figueiredo

2006-12-01

Full Text Available Na microrregião de Viçosa - MG, a criação de frango de corte via contratos de integração com a PIF-PAF S/A Indústria e Comércio tornou-se fonte adicional de renda para as propriedades rurais de pequeno e médio porte. Assim, este trabalho visou verificar a viabilidade de contratos de integração nessa região; especificamente, pretendeu-se elaborar e analisar um projeto de implantação de um aviário, determinar a rentabilidade do investimento, mensurar os riscos da atividade sob o ponto de vista do integrado e auxiliar a tomada de decisão. Para isso, calcularam-se indicadores de viabilidade econômica do projeto, como Valor Presente Líquido, Taxa Interna de Retorno e Razão Benefício/Custo; além disso, foi feita uma análise de sensibilidade para posterior análise de risco. Os resultados apontaram para a viabilidade econômica do projeto; ademais constatou-se que a sua lucratividade é mais sensível aos componentes da receita do que dos custos, sendo o preço recebido por ave a variável de maior sensibilidade. Percebeu-se também que os contratos de integração não eliminam totalmente o risco da atividade e que a integradora transfere parte do risco de preços ao produtor.The chicken production in Viçosa area is done by integration agreement with Pif Paf Company and it is an important option for increasing the income of small farmers. The objective of this paper is to check the viability of integration agreements. A project of a plant for chicken production was drawn and observed in order to determine its profitability and risks, with the purpose of helping the decision making. The Net Present Value, Internal Rate of Return, Cost/Benefit Ratio, Risk Sensitivity and Risk Analysis were calculated. The results show that the project is feasible and the profitability is more sensitive to changes in production price than changes in production costs. This study also points out that the integration agreement does not eliminate the

Invited review, recent developments in brachytherapy source dosimetry

International Nuclear Information System (INIS)

Meigooni, A.S.

2004-01-01

Application of radioactive isotopes is the treatment of choice around the globe for many cancer sites. In this technique, the accuracy of the radiation delivery is highly dependent on the accuracy of radiation dosimetry around individual brachytherapy sources. Moreover, in order to have compatible clinical results, an identical method of source dosimetry must be employed across the world. This problem has been recently addressed by task group 43 from the American Association of Medical Physics with a protocol for dosimetric characterization of brachytherapy sources. This new protocol has been further updated using published data from international sources, by a new Task Group from the American Association of Medical Physics. This has resulted in an updated protocol known as TG43U1 that has been published in March 2004 issue of Medical Physics. The goal of this presentation is to review the original Task Group 43 protocol and associated algorithms for brachytherapy source dosimetry. In addition, the shortcomings of the original protocol that has been resolved in the updated recommendation will be highlighted. I am sure that this is not the end of the line and more work is needed to complete this task. I invite the scientists to join this task and complete the project, with the hope of much better clinical results for cancer patients

Teachers' Perspectives of the Principals' Invitational Leadership Behaviors, Teacher Job Satisfaction and Principal Effectiveness in High-Poverty Rural Elementary Schools

Science.gov (United States)

Younis, Matthew Christopher Zadin

2017-01-01

The purpose of this study was to examine the impact of Invitational Leadership behaviors on school teacher satisfaction, teacher perceptions of the school principal's performance, and to identify if there was a difference between the levels of inviting behaviors of principals at high-achieving and low-achieving rural schools in North Carolina. The…

Amyotrophic lateral sclerosis presenting with orthopnea in a patient with COPD and obstructive sleep apnea

Directory of Open Access Journals (Sweden)

T.L.N. Swamy

2011-01-01

Full Text Available Amyotrophic lateral sclerosis (ALS, also known as motor neuron disease (MND is a relentlessly progressive neurological disorder causing peripheral muscular weakness and resultant respiratory failure. In this article, we report a case of ALS with chronic obstructive pulmonary disease (COPD and obstructive sleep apnea (OSA with orthopnea as initial symptoms.

Airway inflammation in patients affected by obstructive sleep apnea syndrome.

Science.gov (United States)

Salerno, F G; Carpagnano, E; Guido, P; Bonsignore, M R; Roberti, A; Aliani, M; Vignola, A M; Spanevello, A

2004-01-01

Obstructive sleep apnea syndrome (OSAS) has been shown to be associated to upper airway inflammation. The object of the present study was to establish the presence of bronchial inflammation in OSAS subjects. In 16 subjects affected by OSAS, and in 14 healthy volunteers, airway inflammation was detected by the cellular analysis of the induced sputum. OSAS patients, as compared to control subjects, showed a higher percentage of neutrophils (66.7+/-18.9 vs. 25.8+/-15.6) (Pbronchial inflammation characterized by a significant increase in neutrophils.

Rheological, pasting, thermal and retrogradation properties of octenyl succinic anhydride modified potato starch

Directory of Open Access Journals (Sweden)

Chuin WON

Full Text Available Abstract The objective of the present study was to investigate the rheological, pasting, and thermal properties of octenyl succinic anhydrate (OSA-modified potato starch. Potato starch was modified using different concentrations of OSA (0, 1, 3, and 5%, v/v. The degree of substitution (DS for the OSA-modified starch ranged from 0.0012 to 0.0055. The amylose leaching values of native and OSA-modified potato starch with different DS levels were in the range of 47.09-87.32%. The gel strength values of the OSA-modified starch were lower than those of native potato starch. Rapid Visco Analyzer data showed that peak, hot pasting, final and setback viscosities of the native starch decreased after OSA modification. Dynamic shear rheological tests, conducted at 4 °C, indicated that OSA-modified potato starch had weak gel-like behavior with the storage moduli (G' higher than the loss moduli (G” over most of the frequency ranges (0.63-63.8 rad·s-1.

Estado actual de contaminación con coliformes fecales de los cuerpos de agua de la Península de Osa

Directory of Open Access Journals (Sweden)

Jesús Mora

2010-12-01

Full Text Available La contaminación de los cuerpos de aguaen Costa Rica y en todo el mundo es unode los principales problemas ambientales,debido a la importancia estratégicade este recurso. El recurso hídrico esun elemento esencial no solo para lapreservación de la vida, sino también parala conservación de la flora y fauna de laregión.Su conservación y su calidad estánestrechamente vinculadas, prácticamente,a todas las actividades económicas ysociales en forma ineludible, así como a lasalud de su población.La Península de Osa se ha caracterizadopor ser una zona con una exuberantebiodiversidad, tanto en su flora comoen su fauna, raramente encontrada enuna zona pequeña.En 1975, se creó elParque Nacional de Corcovado,el más importante parque de Costa Rica y queprotege a un tercio de la península. Esteexótico territorio que es la Península deOsa no está exento de amenazas, debido ala fragmentación y destrucción del hábitat,la deforestación por la explotación de lamadera y el mal planeamiento en el uso dela tierra, la extracción ilegal de recursos,entre ellos el oro, y el crecimiento de lapoblación en sus alrededores.El Reglamento para la evaluación y laclasificación de la calidad de cuerpos deagua superficiales establece como límiteen el contenido de coliformes fecalesen el agua para actividades recreativasde contacto primario, un valor de 1000(NMP/100mL. Este mismo valor máximose aplica para el riego de hortalizas yotros alimentos que se consumen crudos;mientras que para el uso en abrevaderosy actividades pecuarias el valor máximopermisible de coliformes fecales es de2000, por mencionar algunos casos.Se realizó un estudio sobre la contaminaciónmicrobiológica, utilizando como indicador                                                          el contenido de coliformes fecales

Participation in Education as an Invitation to Become towards the World: Hannah Arendt on the Authority, Thoughtfulness and Imagination of the Educator

Science.gov (United States)

Veck, Wayne

2013-01-01

This article draws on Hannah Arendt's analysis of authority in education, along with her insights into the workings of the imagination and the thinking process, to argue that participation in education should be conceived as an invitation to become towards the world. The potential of this invitation, the article argues, is located in the…

Effects of Personalization and Invitation Email Length on Web-Based Survey Response Rates

Science.gov (United States)

Trespalacios, Jesús H.; Perkins, Ross A.

2016-01-01

Individual strategies to increase response rate and survey completion have been extensively researched. Recently, efforts have been made to investigate a combination of interventions to yield better response rates for web-based surveys. This study examined the effects of four different survey invitation conditions on response rate. From a large…

Comparison of lingual tonsil size as depicted on MR imaging between children with obstructive sleep apnea despite previous tonsillectomy and adenoidectomy and normal controls

Energy Technology Data Exchange (ETDEWEB)

Fricke, Bradley L. [Cincinnati Children' s Hospital Medical Center, Department of Radiology, Cincinnati, OH (United States); Emory University School of Medicine, Department of Radiology, Atlanta, GA (United States); Donnelly, Lane F. [Cincinnati Children' s Hospital Medical Center, Department of Radiology, Cincinnati, OH (United States); Cincinnati Children' s Hospital Medical Center, Department of Pediatrics, Cincinnati, OH (United States); Shott, Sally R. [Cincinnati Children' s Hospital Medical Center, Division of Otolaryngology, Cincinnati, OH (United States); Kalra, Maninder; Poe, Stacy A.; Chini, Barbara A.; Amin, Raouf S. [Cincinnati Children' s Hospital Medical Center, Department of Pediatrics, Cincinnati, OH (United States)

2006-06-15

Cine MRI has become a useful tool in the evaluation of patients with persistent obstructive sleep apnea (OSA) despite previous surgical intervention and in patients with underlying conditions that render them susceptible to multilevel airway obstruction. Findings on cine MRI studies have also increased our understanding of the mechanisms and anatomic causes of OSA in children. To compare lingual tonsil size between children with OSA and a group of normal controls. In addition, a subanalysis was made of the group of children with OSA comparing lingual tonsils between children with and without underlying Down syndrome. Children with persistent OSA despite previous palatine tonsillectomy and adenoidectomy and controls without OSA underwent MR imaging with sagittal fast spin echo inversion-recovery images, and lingual tonsils were categorized as nonperceptible at imaging or present and measurable. When present, lingual tonsils were measured in the maximum anterior-posterior diameter. If lingual tonsils were greater than 10 mm in diameter and abutting both the posterior border of the tongue and the posterior pharyngeal wall, they were considered markedly enlarged. There were statistically significant differences between the OSA and control groups for the presence vs. nonvisualization of lingual tonsils (OSA 33% vs. control 0%, P=0.0001) and mean diameter of the lingual tonsils (OSA 9.50 mm vs. control 0.0 mm, P=0.00001). Within the OSA group, there were statistically significant differences between children with and without Down syndrome for the three lingual tonsil width categories (P=0.0070) and occurrence of markedly enlarged lingual tonsils (with Down syndrome 35% vs. without Down syndrome 3%, P=0.0035). Enlargement of the lingual tonsils is relatively common in children with persistent obstructive sleep apnea after palatine tonsillectomy and adenoidectomy. This is particularly true in patients with Down syndrome. (orig.)

Comparison of lingual tonsil size as depicted on MR imaging between children with obstructive sleep apnea despite previous tonsillectomy and adenoidectomy and normal controls

International Nuclear Information System (INIS)

Fricke, Bradley L.; Donnelly, Lane F.; Shott, Sally R.; Kalra, Maninder; Poe, Stacy A.; Chini, Barbara A.; Amin, Raouf S.

2006-01-01

Cine MRI has become a useful tool in the evaluation of patients with persistent obstructive sleep apnea (OSA) despite previous surgical intervention and in patients with underlying conditions that render them susceptible to multilevel airway obstruction. Findings on cine MRI studies have also increased our understanding of the mechanisms and anatomic causes of OSA in children. To compare lingual tonsil size between children with OSA and a group of normal controls. In addition, a subanalysis was made of the group of children with OSA comparing lingual tonsils between children with and without underlying Down syndrome. Children with persistent OSA despite previous palatine tonsillectomy and adenoidectomy and controls without OSA underwent MR imaging with sagittal fast spin echo inversion-recovery images, and lingual tonsils were categorized as nonperceptible at imaging or present and measurable. When present, lingual tonsils were measured in the maximum anterior-posterior diameter. If lingual tonsils were greater than 10 mm in diameter and abutting both the posterior border of the tongue and the posterior pharyngeal wall, they were considered markedly enlarged. There were statistically significant differences between the OSA and control groups for the presence vs. nonvisualization of lingual tonsils (OSA 33% vs. control 0%, P=0.0001) and mean diameter of the lingual tonsils (OSA 9.50 mm vs. control 0.0 mm, P=0.00001). Within the OSA group, there were statistically significant differences between children with and without Down syndrome for the three lingual tonsil width categories (P=0.0070) and occurrence of markedly enlarged lingual tonsils (with Down syndrome 35% vs. without Down syndrome 3%, P=0.0035). Enlargement of the lingual tonsils is relatively common in children with persistent obstructive sleep apnea after palatine tonsillectomy and adenoidectomy. This is particularly true in patients with Down syndrome. (orig.)

Pulse oximetry recorded from the Phone Oximeter for detection of obstructive sleep apnea events with and without oxygen desaturation in children.

Science.gov (United States)

Garde, Ainara; Dehkordi, Parastoo; Wensley, David; Ansermino, J Mark; Dumont, Guy A

2015-01-01

Obstructive sleep apnea (OSA) disrupts normal ventilation during sleep and can lead to serious health problems in children if left untreated. Polysomnography, the gold standard for OSA diagnosis, is resource intensive and requires a specialized laboratory. Thus, we proposed to use the Phone Oximeter™, a portable device integrating pulse oximetry with a smartphone, to detect OSA events. As a proportion of OSA events occur without oxygen desaturation (defined as SpO2 decreases ≥ 3%), we suggest combining SpO2 and pulse rate variability (PRV) analysis to identify all OSA events and provide a more detailed sleep analysis. We recruited 160 children and recorded pulse oximetry consisting of SpO2 and plethysmography (PPG) using the Phone Oximeter™, alongside standard polysomnography. A sleep technician visually scored all OSA events with and without oxygen desaturation from polysomnography. We divided pulse oximetry signals into 1-min signal segments and extracted several features from SpO2 and PPG analysis in the time and frequency domain. Segments with OSA, especially the ones with oxygen desaturation, presented greater SpO2 variability and modulation reflected in the spectral domain than segments without OSA. Segments with OSA also showed higher heart rate and sympathetic activity through the PRV analysis relative to segments without OSA. PRV analysis was more sensitive than SpO2 analysis for identification of OSA events without oxygen desaturation. Combining SpO2 and PRV analysis enhanced OSA event detection through a multiple logistic regression model. The area under the ROC curve increased from 81% to 87%. Thus, the Phone Oximeter™ might be useful to monitor sleep and identify OSA events with and without oxygen desaturation at home.

Osteocalcin and Osteonectin Expression in Canine Osteosarcoma.

Science.gov (United States)

Wehrle-Martinez, A S; Dittmer, K E; Aberdein, D; Thompson, K G

2016-07-01

Osteosarcoma (OSA) is a malignant heterogeneous primary bone tumor responsible for up to 90% of all primary bone tumors in dogs. In this study, osteocalcin (OC) and osteonectin (ON) immunoreactivity was evaluated in 23 canine OSAs, 4 chondrosarcomas, 4 fibrosarcomas, 2 hemangiosarcomas, and 4 histiocytic sarcomas. The effects of three different decalcification agents (ethylenediaminetetraetic acid [EDTA], formic acid and hydrochloric acid [HCl]) on the immunoreactivity for OC and ON was also assessed. Immunoreactivity to OC was present in 19/23 (83%) cases of OSA and all cases of chondrosarcoma. In three OSAs the extracellular matrix showed immunoreactivity to OC. None of the fibrosarcomas, histiocytic sarcomas or hemangiosarcomas showed immunoreactivity to OC. The sensitivity and specificity for OC in canine OSA in this study was 83% and 71% respectively. For ON, 100% of both OSAs (23/23) and non-OSAs (14/14) showed cytoplasmic immunoreactivity to this antibody, giving a sensitivity of 100% but a complete lack of specificity. There were no significant differences in immunoreactivity for OC and ON between the different decalcification agents used. In conclusion, OC showed high sensitivity for identifying OSA but it failed to distinguish between OSA and chondrosarcoma, and the osteoid produced by neoplastic cells in most cases did not show immunoreactivity to OC. These factors may limit the practical utility of OC in the diagnosis of OSA in dogs when chondrosarcoma is a differential diagnosis. ON showed no specificity in detecting OSA and has little practical application for the diagnosis of OSA in dogs. © The Author(s) 2016.

Scarlet Macaw (Ara macao, Psittaciformes: Psittacidae Nest Characteristics in the Osa Peninsula Conservation Area (ACOSA, Costa Rica

Directory of Open Access Journals (Sweden)

John L Guittar

2009-06-01

Full Text Available The Scarlet Macaw (Ara macao is an endangered species. In Costa Rica, the Scarlet Macaw population of the Central Pacific Conservation Area (ACOPAC, n =432 individuals has undergone considerable study and has been used effectively as a flagship species for regional conservation. Costa Rica’s only other viable Scarlet Macaw population, located in the Osa Peninsula Conservation Area (ACOSA, n=800-1200 individuals, remains virtually unstudied. We studied ACOSA Scarlet Macaw nest cavities from February 19th to March 22nd 2006. Through informal interviews with park guards and residents, we found a total of 57 potential nests in 52 trees. Eleven nests were reported as frequently poached. Scarlet Macaws used 14 identified tree species, ten of which are unrecorded in Costa Rica. The most common nesting trees were Caryocar costaricense (n=12, 24%, Schizolobium parahyba (n=9, 18.0%, Ceiba pentandra (n=7, 14.0% and Ficus sp. (n=5, 10.0%. We compare nesting characteristics to those recorded in ACOPAC. A combination of bottom-up and top-down strategies are necessary to ensure the Scarlet Macaw’s long-term success, including environmental education in local schools, community stewardship of active nests, and the advertisement of stricter penalties for poaching. Rev. Biol. Trop. 57 (1-2: 387-393. Epub 2009 June 30.

Invitation systems and identification in Late Iron Age southern Scandinavia? The gold foil figures from a new perspective

DEFF Research Database (Denmark)

Baastrup, Maria Panum

2016-01-01

of a person’s true identity and in the dependency upon magnates in southern Scandinavia during the 6th–8th centuries AD. The gold foil figures may have been tokens issued by the magnate and served as invitations to special events, at a time when there was apparently a preoccupation with organising cult...... activities at the elite residences and restricting places at and admission to such events. The figures did not guarantee that it was the right guests who arrived on these occasions, but presenting this type of token may have minimised the risk of allowing in impostors....

Resumen de tesis. El régimen jurídico de la publicidad engañosa por omisión: especial referencia a los derechos mexicano y español

OpenAIRE

Gómez Anel, María Isabel

2015-01-01

[ES] La investigación doctoral analiza el régimen legal de la publicidad engañosa por omisión llevando a cabo un análisis comparativo de los ordenamientos jurídicos español y mexicano. En primer término se aborda la publicidad en el marco de la tutela de los consumidores, los derechos fundamentales extensivos a la publicidad comercial y los principios básicos que las comunicaciones comerciales deben cubrir en torno a la protección jurídica de los consumidores. Es analizada la publicidad il...

An Advanced Private Social Activity Invitation Framework with Friendship Protection

Directory of Open Access Journals (Sweden)

Weitian Tong

2017-01-01

Full Text Available Due to the popularity of social networks and human-carried/human-affiliated devices with sensing abilities, like smartphones and smart wearable devices, a novel application was necessitated recently to organize group activities by learning historical data gathered from smart devices and choosing invitees carefully based on their personal interests. We proposed a private and efficient social activity invitation framework. Our main contributions are (1 defining a novel friendship to reduce the communication/update cost within the social network and enhance the privacy guarantee at the same time; (2 designing a strong privacy-preserving algorithm for graph publication, which addresses an open concern proposed recently; (3 presenting an efficient invitee-selection algorithm, which outperforms the existing ones. Our simulation results show that the proposed framework has good performance. In our framework, the server is assumed to be untrustworthy but can nonetheless help users organize group activities intelligently and efficiently. Moreover, the new definition of the friendship allows the social network to be described by a directed graph. To the best of our knowledge, it is the first work to publish a directed graph in a differentially private manner with an untrustworthy server.

Perioperative management of children with obstructive sleep apnea.

Science.gov (United States)

Schwengel, Deborah A; Sterni, Laura M; Tunkel, David E; Heitmiller, Eugenie S

2009-07-01

Obstructive sleep apnea syndrome (OSA) affects 1%-3% of children. Children with OSA can present for all types of surgical and diagnostic procedures requiring anesthesia, with adenotonsillectomy being the most common surgical treatment for OSA in the pediatric age group. Thus, it is imperative that the anesthesiologist be familiar with the potential anesthetic complications and immediate postoperative problems associated with OSA. The significant implications that the presence of OSA imposes on perioperative care have been recognized by national medical professional societies. The American Academy of Pediatrics published a clinical practice guideline for pediatric OSA in 2002, and cited an increased risk of anesthetic complications, though specific anesthetic issues were not addressed. In 2006, the American Society of Anesthesiologists published a practice guideline for perioperative management of patients with OSA that noted the pediatric-related risk factor of obesity, and the increased perioperative risk associated with adenotonsillectomy in children younger than 3 yr. However, management of OSA in children younger than 1 yr-of-age was excluded from the guideline, as were other issues related specifically to the pediatric patient. Hence, many questions remain regarding the perioperative care of the child with OSA. In this review, we examine the literature on pediatric OSA, discuss its pathophysiology, current treatment options, and recognized approaches to perioperative management of these young and potentially high-risk patients.

Presentation of Knovel - technical information portal for the engineering community | 15 February

CERN Multimedia

CERN Library

2013-01-01

The Library invites you to a presentation of Knovel, given by Gary Kearns, Knovel Managing Director - EMEA.   Friday 15 February 2013 from 11:00 to 12:30 room 30-7-018 (Kjell Johnsen Auditorium) Knovel is a web-based discovery platform meeting the information needs of the engineering community. It combines the functionalities of an ebooks platform and of a search engine querying a plurality of online databases. These functionalities are complemented by analytical tools that permit to extract and manipulate data from ebooks content. The agenda of the presentation is available here.

Condições de serventia de estradas não-pavimentadas: estudo de caso aplicado às vias do município de Viçosa, Estado de Minas Gerais, Brasil = Serviceability of unpaved roads: a case study applied to net road from Viçosa, Minas Gerais

Directory of Open Access Journals (Sweden)

Taciano Oliveira da Silva

2011-04-01

Full Text Available Este artigo apresenta a adaptação do método de classificação de estradas nãopavimentadas proposto por Eaton às condições encontradas em rodovias vicinais do município de Viçosa, Estado de Minas Gerais, considerando a sua potencialidade como ferramenta de suporte à gerência destas vias. Este estudo foi desenvolvido a partir deavaliações objetiva, realizada com o emprego de uma escala de notas, e subjetiva, em obediência à metodologia de Eaton, que foram conduzidas por uma equipe treinada previamente que executou inspeções de campo, atribuindo notas a 20 unidades amostrais, possuindo cada uma delas 50 m de comprimento e representativas de 10 trechos analisados de vias não-pavimentadas. A análise dos dados desta pesquisa possibilitou concluir que: (i não houve correlação entre os resultados das avaliações subjetiva e objetiva, e a aplicação dametodologia de Eaton à gerência de manutenção de vias não-pavimentadas pode não refletir as suas prioridades reais; (ii a avaliação subjetiva do trecho e a avaliação subjetiva do conjunto de suas unidades amostrais são correlatas, indicando ser coerente o emprego deste procedimento.This paper addresses the adaptation of the method of classification of unpaved roads developed by Eaton to the field conditions of local roads from the city of Viçosa, Minas Gerais State, Brazil, considering its potential as a support tool for the management of these roads. This study was developed encompassing objective evaluation, carried out with the application of a note scale, and subjective evaluation, according to the methodology of Eaton, which were performed by a team that accomplished the field inspections, attributing notes to the 20 sample units, each one 50 meters long andrepresenting 10 analyzed unpaved road segments. Conclusions are as follows: (i it was not observed any correlation between data from the objective and the subjective field evaluations, leading to the conclusion

[Quality of life in patients with obstructive sleep apnea].

Science.gov (United States)

Kasibowska-Kuźniar, Kamilla; Jankowska, Renata; Kuźniar, Tomasz

2004-11-01

Obstructive sleep apnea syndrome (OSA) is a condition affecting up to 5% of the population, in which episodes of upper airway obstruction lead to temporary cessation of airflow, disturbed sleep architecture and daily somnolence. The health consequences of OSA also include psychological and cognitive deficits, an increased risk of systemic and pulmonary hypertension, coronary disease, bradyarrhythmias and motor vehicle accidents. Symptoms and complications of OSA lead to a significant decrease of health-related quality of life (HRQOL) of affected patients. We review the current literature on HRQOL effects of OSA and its treatment. There is good evidence of beneficial effect of the continuous positive airway pressure (CPAP) therapy on the quality of life of patients with OSA. Improvements in HRQOL are most appreciable in patients with moderate to severe OSA, although they also seem to be present in selected patients with mild OSA. The effects of dental devices and surgical procedures on HRQOL of patients with OSA have not been studied in randomized, placebo-controlled trials. Health-related quality of life has become one of the major outcome measures in patients with sleep apnea. Assessment of HRQOL has become a crucial part of any clinical study involving patients with OSA.

Downregulation of connective tissue growth factor reduces migration and invasiveness of osteosarcoma cells.

Science.gov (United States)

Huang, Yinjun; Zhao, Shichang; Zhang, Changqing; Li, Xiaolin

2016-02-01

As one of the most serious types of primary bone tumor, osteosarcoma (OSA) features metastatic lesions, and resistance to chemotherapy is common. The underlying mechanisms of these characteristics may account for the failure of treatments and the poor prognosis of patients with OSA. It has been reported that inhibition of Cyr61 suppresses OSA cell proliferation as it represents a target of statins. In addition to cystein‑rich protein 61 (Cyr61) and nephroblastoma overexpression, connective tissue growth factor (CTGF) is a member of the CCN family and may therefore exhibit effects on human OSA cells similar to those of Cyr61. In the current study, acridine orange/ethidium bromide staining were used to determine the rate of apoptosis. The present study demonstrated that small interfering RNA‑mediated silencing of CTGF promoted cell death and suppressed OSA cell migration and invasion, as indicated by wound healing and Transwell assays, while lentivirus‑mediated overexpression of CTGF reversed these effects. Furthermore, a colorimetric caspase assay demonstrated that CTGF knockdown enhanced the efficacy of chemotherapeutic drugs. The results of the present study provided a novel molecular target which may be utilized for the treatment of metastatic OSA.

Carotenos e provitamina A em bertalha e ervas aromáticas comercializadas em Viçosa, Estado de Minas Gerais, durante as quatro estações do ano - DOI: 10.4025/actascihealthsci.v28i1.1122 Carotenes and provitamin A in basella and aromatic herbs marketed in Viçosa, Minas Gerais State, during the four seasons of the year - DOI: 10.4025/actascihealthsci.v28i1.1122

Directory of Open Access Journals (Sweden)

José Benício Paes Chaves

2006-03-01

Full Text Available Este estudo teve como objetivos investigar o teor de α-caroteno, β-caroteno e calcular o valor de vitamina A em hortaliças comercializadas no mercado formal e informal de Viçosa, Estado de Minas Gerais, bem como avaliar a influência das quatro estações do ano e do local de comercialização sobre o conteúdo desses nutrientes. As hortaliças (bertalha, cebolinha, coentro, manjericão e salsa foram analisadas utilizando-se a cromatografia líquida de alta eficiência (CLAE. Devido ao conteúdo inexpressivo de α-caroteno em todas as amostras, foi possível quantificar apenas o β-caroteno. Não se verificou diferença estatisticamente significativa (α = 0,05 no conteúdo de β-caroteno das hortaliças entre os diferentes estabelecimentos, nem entre as estações do ano. As hortaliças mostraram-se excelentes fontes de provitamina A, e se consumidas regularmente, contribuem de forma importante na adequação diária de vitamina A para adultos e crianças. Além disso, esses alimentos são acessíveis à população por apresentarem baixo custo e serem facilmente encontrados.This study aimed to investigate the level of α-carotene, β-carotene and to calculate the value of vitamin A in vegetables sold at local markets and informal markets of Viçosa, Minas Gerais State, as well as to evaluate the seasonal and commercial effects on the content of these pigments. The vegetables (basella, green onion, cilantro, sweet basil and parsley were analyzed through high-performance liquid chromatography (HPLC, being β-carotene the only pigment present in all the analyzed samples. No significant statistical differences (α = 0.05 were found in the contents of β-carotene of the vegetables either among the different stores, or among the different seasons. The vegetables analyzed are great provitamin A sources and, if eaten on a regular basis, they can fit the daily requirements of vitamin A for adults and children. Besides, these foods are very

77 FR 31432 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel PASSION; Invitation for...

Science.gov (United States)

2012-05-25

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2012 0062] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel PASSION; Invitation for Public Comments AGENCY... PASSION is: Intended Commercial Use of Vessel: ``Bareboat chartering, sailing classes.'' Geographic Region...

76 FR 75948 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel CHRYSALIS; Invitation for...

Science.gov (United States)

2011-12-05

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011 0149] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel CHRYSALIS; Invitation for Public Comments AGENCY... CHRYSALIS is: Intended Commercial Use of Vessel: ``Weekly charter vessel.'' Geographic Region: ``Florida...

Association between QRS duration and obstructive sleep apnea.

Science.gov (United States)

Gupta, Shuchita; Cepeda-Valery, Beatriz; Romero-Corral, Abel; Shamsuzzaman, Abu; Somers, Virend K; Pressman, Gregg S

2012-12-15

Both obstructive sleep apnea (OSA) and prolonged QRS duration are associated with hypertension, heart failure, and sudden cardiac death. However, possible links between QRS duration and OSA have not been explored. Cross-sectional study of 221 patients who underwent polysomnography at our center. Demographics, cardiovascular risk factors and ECG were collected to explore a relationship between OSA and QRS duration. The apnea-hypopnea index (AHI) was positively correlated with QRS duration (r = 0.141, p = 0.03). Patients were divided into 3 groups: AHI 30 (55). The mean QRS duration prolonged significantly as OSA worsened (AHI 30, 95 ± 19.9 ms, p = 0.001). QRS ≥ 100 ms was present in 12.7% of patients with severe OSA compared with 0% in the rest of the sample (p < 0.0001). After adjustment for age, race, and cardiovascular risk factors, this association remained significant in women but not in men. QRS duration and OSA were significantly associated. Severity of OSA independently predicted prolonged QRS in women but not men. Nevertheless, prolongation of QRS duration in either sex may potentiate arrhythmic risks associated with OSA.

Cellular and Phenotypic Characterization of Canine Osteosarcoma Cell Lines

Directory of Open Access Journals (Sweden)

Marie E. Legare, Jamie Bush, Amanda K. Ashley, Taka Kato, William H. Hanneman

2011-01-01

Full Text Available Canine and human osteosarcoma (OSA have many similarities, with the majority of reported cases occurring in the appendicular skeleton, gender predominance noted, high rate of metastasis at the time of presentation, and a lack of known etiology for this devastating disease. Due to poor understanding of the molecular mechanisms underlying OSA, we have characterized seven different OSA canine cell lines: Abrams, D17, Grey, Hughes, Ingles, Jarques, and Marisco and compared them to U2, a human OSA cell line, for the following parameters: morphology, growth, contact inhibition, migrational tendencies, alkaline phosphatase staining, heterologous tumor growth, double-strand DNA breaks, and oxidative damage. All results demonstrated the positive characteristics of the Abrams cell line for use in future studies of OSA. Of particular interest, the robust growth of a subcutaneous tumor and rapid pulmonary metastasis of the Abrams cell line in an immunocompromised mouse shows incredible potential for the future use of Abrams as a canine OSA model. Further investigations utilizing a canine cell model of OSA, such as Abrams, will be invaluable to understanding the molecular events underlying OSA, pharmaceutical inhibition of metastasis, and eventual prevention of this devastating disease.

78 FR 39061 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel MISTRESS MALLIKA; Invitation...

Science.gov (United States)

2013-06-28

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0076] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel MISTRESS MALLIKA; Invitation for Public Comments AGENCY... MISTRESS MALLIKA is: Intended Commercial Use Of Vessel: ``Pleasure Charters''. Geographic Region: Rhode...

Diversidade e equitabilidade de Plantas Alimentícias Não Convencionais na zona rural de Viçosa, Minas Gerais, Brasil

Directory of Open Access Journals (Sweden)

T.F. BARREIRA

2015-01-01

Full Text Available RESUMO O presente estudo analisou a diversidade e equitabilidade de plantas alimentícias não convencionais (PANCs na zona rural de Viçosa, Minas Gerais, Brasil. A pesquisa foi conduzida utilizando a amostragem Bola de Neve com entrevistas semiestruturadas aplicadas à 20 moradores de nove comunidades rurais. Avaliou-se a frequência relativa de citação das espécies (Fr; a diversidade e equitabilidade das mesmas, utilizando os índices de Shannon-Wiener (H’ e de Pielou (J’, respectivamente. As espécies foram listadas pela família, nome científico, nomes populares, ambiente de propagação, hábito de crescimento, formas de consumo, estado de domesticação, ciclo de produção e registro por meio de consultas em herbários do bioma Mata Atlântica. Foram encontradas 59 espécies de PANCs, distribuídas em 30 famílias botânicas e 48 gêneros. As famílias asteraceae e myrtaceae se destacaram pela riqueza florística, contribuindo com 11 e 7 espécies, respectivamente. Espécies da família asteraceae obtiveram as maiores frequências relativas (32,2. Obteve-se índice de diversidade Shannon-Wiener de 1,65 (Base 10, e de equitabilidade de Pielou de 0,93. Os resultados encontrados estão similares à de outros estudos desenvolvidos no bioma Mata Atlântica, observou-se ampla diversidade de PANCs na área de estudo, e o conhecimento sobre estas encontra-se distribuído uniformemente entre os moradores.

Chronic obstructive pulmonary disease severity and its association with obstructive sleep apnea syndrome: impact on cardiac autonomic modulation and functional capacity

Directory of Open Access Journals (Sweden)

Zangrando KTL

2018-04-01

Full Text Available Katiany Thays Lopes Zangrando,1 Renata Trimer,2 Luiz Carlos Soares de Carvalho Jr,1 Guilherme Peixoto Tinoco Arêas,1 Flávia Cristina Rossi Caruso,1 Ramona Cabiddu,1 Meliza Goi Roscani,3 Fabíola Paula Galhardo Rizzatti,3 Audrey Borghi-Silva1 1Cardiopulmonary Physiotherapy Laboratory, Physiotherapy Department, Federal University of São Carlos, São Carlos, São Paulo, Brazil; 2Physical Education and Health Department, University of Santa Cruz do Sul, Santa Cruz do Sul, Rio Grande do Sul, Brazil; 3Medicine Department, Federal University of São Carlos, São Carlos, São Paulo, Brazil Background: The study was conducted to determine the impact of chronic obstructive pulmonary disease (COPD in association with obstructive sleep apnea syndrome (OSAS on cardiac autonomic control and functional capacity. Subjects and methods: The study was a cross-sectional prospective controlled clinical study. Heart rate variability indices of 24 COPD (n = 12 and COPD+OSAS (n = 12 patients were evaluated and compared by electrocardiographic recordings acquired during rest, active postural maneuver (APM, respiratory sinus arrhythmia maneuver (RSA-m, and the 6-minute walk test (6MWT. Results: The COPD group presented higher parasympathetic modulation during APM when compared to the COPD+OSAS group (P = 0.02. The COPD+OSAS group presented higher sympathetic modulation during RSA-m when compared to the COPD group (P = 0.00. The performance during 6MWT was similarly impaired in both groups, despite the greater severity of the COPD group. Conclusion: Subjects with COPD+OSAS present marked sympathetic modulation, and the presence of OSAS in COPD subjects has a negative impact on functional capacity regardless of the severity of lung disease. Keywords: COPD, OSAS, COPD+OSAS, functional capacity

Fatores socioeconômicos da produção de queijo minas frescal em agroindústrias familiares de Viçosa, MG Socioeconomic factors in the production of fresh cheese in family agribusiness of Viçosa, MG, Brazil

Directory of Open Access Journals (Sweden)

Mariana Barboza Vinha

2010-09-01

Full Text Available A produção de queijo minas frescal em agroindústrias familiares é amplamente difundida no Estado de Minas Gerais (MG associada à tradição cultural, à demanda do consumidor e ao rendimento do produto. Os objetivos deste estudo foram avaliar aspectos socioeconômicos da produção de queijos minas frescal fabricados em agroindústrias familiares no município de Viçosa-MG e caracterizar as principais dificuldades do setor. Os dados foram levantados pelo método de entrevista in loco em 12 agroindústrias, seis inspecionadas e seis não inspecionadas A renda do produtor familiar proveniente da produção do queijo minas frescal variou de 10 a 85% do total da renda familiar, com maiores percentuais para as agroindústrias inspecionadas. Em 83% das agroindústrias inspecionadas, a renda total era vinculada principalmente à produção do queijo. Os entraves na produção formal incluíram a competição com produtos informais, o baixo preço e a dificuldade de acesso a linhas de crédito e, para os produtores informais, incluíram escassez de matéria-prima e de mão de obra, variação sazonal da produção e ausência de infraestrutura adequada para produção. A produção de queijo minas frescal é uma atividade relevante na composição da renda familiar das agroindústrias, entretanto há necessidade de implementação de políticas públicas locais para melhor estruturação do setor, o que contribuirá para a sustentabilidade da produção familiar.The production of minas frescal cheese in familiar agribusiness is widely diffused in Minas Gerais State, associated to cultural tradition, consumer demand and product yield. The objectives of this study were to evaluate socioeconomic aspects on the production of minas frescal cheese produced in familiar agroindustries in the city of Viçosa-MG, Brazil and to characterize the main difficulties in this sector. Data were collected by the in loco interview method in 12 agribussiness, six of

"Just Don't": The Suppression and Invitation of Dialogue in the Mathematics Classroom

Science.gov (United States)

Wagner, David; Herbel-Eisenmann, Beth

2008-01-01

Responding to concerns raised by grade 11 mathematics students, we examined a broad set of mathematics classroom transcripts from multiple teachers to examine how the word "just" was and could be used to suppress and invite dialogue. We used corpus linguistics tools to process and quantify the large body of text, not to describe the nature of the…

INFLUÊNCIA DOS FATORES EDÁFICOS NA VARIAÇÃO FLORÍSTICA DE FLORESTA ESTACIONAL SEMIDECIDUAL, EM VIÇOSA, MG

Directory of Open Access Journals (Sweden)

Antonio Jorge Tourinho Braga

2015-08-01

Full Text Available RESUMOO objetivo deste estudo foi verificar a possível correlação dos fatores edáficos na distribuição dos indivíduos de espécies arbóreas e a similaridade florística entre as populações, em dois trechos distintos de um fragmento de Floresta Estacional Semidecidual, em Viçosa, MG (20°46' S e 42°52' W. No trabalho, foram amostrados os indivíduos arbóreos superiores ou iguais a 15 cm (CAP, presentes em 20 parcelas de 25×10 m, estando metade dessas alocadas (10 em cada trecho de floresta. Na área das parcelas, foram coletadas amostras de solo (0-10 cm e submetidas às análises química e física. Os resultados dos atributos físicos e químicos do solo indicaram variações conforme as mudanças na topografia do terreno. A análise de correspondência canônica (CCA indicou correlação significativa entre a distribuição das espécies arbóreas avaliadas no perfil topográfico e a fertilidade do solo, enquanto a comparação entre as espécies pertencentes às florestas inicial e avançada apontou baixa similaridade florística. Verificou-se ainda que espécies como Casearia arborea, Ocotea laxa, Myrcia fallax, Siparuna guianensis, Apuleia leiocarpa, Matayba elaeagnoides e Sparattosperma leucanthum estão associadas a solos argilosos mais ácidos, de encostas e com maior teor de alumínio, permitindo o uso delas em programas de recuperação ambiental.

78 FR 46410 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel IMPOSSIBLE DREAM; Invitation...

Science.gov (United States)

2013-07-31

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0084] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel IMPOSSIBLE DREAM; Invitation for Public Comments AGENCY... of the vessel IMPOSSIBLE DREAM is: Intended Commercial Use of Vessel: ``Day, Multiple Day, Week...

Blood donor show behaviour after an invitation to donate : The influence of collection site factors

NARCIS (Netherlands)

Merz, E.-M.; Zijlstra, B.J.H.; de Kort, W.L.A.M.

2017-01-01

Background and Objectives Show behaviour after invitation to donate varies considerably across donors. More insight into this variation is important for blood banks in achieving stable stocks. This study examined individual factors determining intended show behaviour. Most importantly, however, this

Blood donor show behavior after an invitation to donate: The influence of collection site factors

NARCIS (Netherlands)

Merz, E.M.; Zijlstra, Bonne; De Kort, Wim L.A.M.

2017-01-01

Background and Objectives Show behaviour after invitation to donate varies considerably across donors. More insight into this variation is important for blood banks in achieving stable stocks. This study examined individual factors determining intended show behaviour. Most importantly, however, this

Correlation of obstructive sleep apnoea and laryngopharyngeal reflux: phmetry study.

Science.gov (United States)

Elhennawi, D M; Ahmed, M R; Abou-Halawa, A S

2016-12-01

To study the correlation of obstructive sleep apnoea (OSA) and laryngopharyngeal reflux (LPR). A descriptive study. Suez Canal University Hospital, Ismailia, Egypt. 62 patients with polysomnography confirmed OSA. Patients were evaluated with ambulatory 24-h double channel pH monitoring. Mean reflux symptom index in the study group was 9 ± 5.5, and it was > 13 in all patients with severe OSA. Signs of LPR reflux were present in 34 (55%) patients. Abnormal reflux was detected in the distal oesophagus in 41 patients (66%) and in the proximal oesophagus in 21 patients (34%). Patients with severe OSA had significantly higher nocturnal LPR reflux episodes compared to patients with mild disease (P .05). LPR is common in patients with OSA. Patients with severe OSA have significantly higher nocturnal LPR. This should be considered when treating this group of patients. © 2016 John Wiley & Sons Ltd.

78 FR 23893 - Notice of Funds Availability: Inviting Applications for the Market Access Program

Science.gov (United States)

2013-04-23

... inviting proposals for the 2014 Market Access Program (MAP). The intended effect of this notice is to... strategy and a program effectiveness time line against which results can be measured at specific intervals... allocation strategy to fund applicants who can demonstrate performance and address the objectives of the GPRA...

Impact of postal invitations and user fee on influenza vaccination rates among the elderly. A randomized controlled trial in general practice

DEFF Research Database (Denmark)

Nexøe, J; Kragstrup, J; Rønne, T

1997-01-01

, compared with 49% (42-56%) in the group who received a postal reminder and paid the usual fee, and 72% (65-78%) in the group invited to be vaccinated free of charge. CONCLUSION: It is suggested that GPs send postal invitations to their elderly patients in the risk groups urgently recommending influenza...... vaccination. Attention should also be given to offering free influenza vaccination to elderly patients who have recognized indications for vaccination. Udgivelsesdato: 1997-Jun...

Ambulatory positional obstructive sleep apnea syndrome

Directory of Open Access Journals (Sweden)

Fernando Di-Tullio

Full Text Available Objective: To establish the prevalence of positional (PP OSA patients using self-administered home-based respiratory polygraphy (RP. Materials and Methods: 52 month retrospective study based on RP records. Results: 200 PR records: 70.5% men 29.5% women. 76% were diagnosed with OSA and 54.6% with PP OSA. There were no significant differences in Epworth Sleepiness Scale, apnea hypopnea index and oxygen desaturation index. PP OSA patients were younger, had a lower BMI (30.3±0.9 vs. 35.3±1.2 (p<0.0001, and the time they spent with oxygen saturation <90% (T<90 was lower (8.8 vs. 28.7±6.7, p=0.0038. The PP OSA group spent 43% of total recording time in the supine position. Conclusions: The prevalence of PP OSA patients studied with RP is similar to the one described by sleep laboratories. They have lower BMI, present mostly mild OSA with less desaturation, and are less likely to receive CPAP therapy.

Obstructive sleep apnea: management considerations in psychiatric patients

Directory of Open Access Journals (Sweden)

Heck T

2015-10-01

Full Text Available Taryn Heck,1 Monica Zolezzi21Pharmacy Department, University of Alberta Hospital, Alberta Health Services, Edmonton, AB, Canada; 2Clinical Pharmacy and Practice, College of Pharmacy, Qatar University, Doha, QatarAbstract: Psychiatric disorders and obstructive sleep apnea (OSA are often comorbid. However, there is limited information on the impact of psychotropic medications on OSA symptoms, on how to manage psychiatric pharmacotherapy in patients presenting with OSA, or on the effectiveness and challenges of OSA treatments in patients with comorbid mental illness. As such, the objective of this article is to provide an overview of some epidemiological aspects of OSA and treatment considerations in the management of OSA in individuals with comorbid psychiatric disorders. Predefined keywords were used to search for relevant literature in electronic databases. Data show that OSA is particularly prevalent in patients with psychiatric disorders. The medical care that patients with these comorbidities require can be challenging, as some of the psychiatric medications used by these patients may exacerbate OSA symptoms. As such, continuous positive airway pressure continues to be the first-line treatment, even in patients with psychiatric comorbidity. However, more controlled studies are required, particularly to determine continuous positive airway pressure compliance in patients with mental illness, the impact of treating OSA on psychiatric symptoms, and the impact of the use of psychotropic medications on OSA symptoms.Keywords: obstructive sleep apnea, psychiatric disorders, comorbidity, psychotropic medications

Summary report of the overseas researcher invitation program in FY1996; 1996 nendo kaigai kenkyusha shohei jigyo hokokusho

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-03-01

To exchange research information, Mr. Koernaen Inif was invited from the Ministry of Industry and Commerce, Indonesia in the period between 4th November in 1996 and 4th February in 1997 as a part of the overseas researcher invitation program in FY 1996. The research theme is `Investigation of low cost removal method of COD and BOD from industrial waste water: Biodegradation of lignin in the waste water from pulp industry using anaerobic bacteria.` The institute of the invited researcher has promoted investigations for improving water quality of the Surabaya River. The largest reason of the water quality pollution of the Surabaya River is caused by the waste water from paper and pulp industry, and pollutants are COD and BOD. In major factories with economic margins, waste water treatments have been conducted, which do not satisfy the waste water standard of factories. In this investigation, the treatment technology information of industrial waste water were collected. The information were summarized for contributing to the future research and development in Surabaya. The objective was to obtain the biodegradation techniques of lignin using anaerobic bacteria. 51 refs., 7 figs., 5 tabs.

76 FR 75949 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel PANGAEA; Invitation for...

Science.gov (United States)

2011-12-05

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011 0150] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel PANGAEA; Invitation for Public Comments AGENCY... PANGAEA is: Intended Commercial Use of Vessel: ``We would like to offer Pangaea for day [[Page 75950...

Formation of oil-SPM aggregates under various mixing intensities

International Nuclear Information System (INIS)

Sun, J.; Zheng, X.

2009-01-01

A considerable amount of petroleum products spill into aquatic ecosystems as a result of increased marine transportation of crude oil products. The oil spill response community is therefore seeking an economical and environmentally sound technology to remove oil from shorelines. The formation of oil-suspended particulate matter (SPM) aggregates (OSAs) occurs when oil and SPM are present in a turbulent system. This process is known to enhance natural cleaning of oiled shorelines by increasing oil dispersion into the water column and accelerating the biodegradation of the oil. This paper reported on a laboratory study that was conducted to investigate OSA formation under different mixing energy levels. It presented the results of experiments conducted with Arabian heavy crude oil, standard reference material 1941b, artificial seawater, and 3 shaking rates of the reciprocating shaker. The results are intended to offer insight into the rate and extent of oil sediment interaction following an oil spill in the marine environment under different mixing conditions. Mixing energy is expected to have a considerable control on OSA formation because it controls the splitting of an oil slick into small droplets, the aggregation between the droplets and SPM, and the breakage rate of natural flocs. The concentration of the OSA was measured using the gas chromatography-flame ionization detection (GC-FID) method. Ultraviolet epi-fluorescence image analysis was used to measure the structure of OSAs and the concentration of oil droplets forming OSAs. The results showed that the formation of OSAs increased as the mixing energy increased. A consistent increase in droplet concentration in OSAs was also noted as the mixing energy increased. Both oil droplet size and OSA size decreased as the mixing intensity increased. 38 refs., 4 tabs., 3 figs.

A cluster randomized trial of strategies to increase uptake amongst young women invited for their first cervical screen: The STRATEGIC trial.

Science.gov (United States)

Kitchener, H; Gittins, M; Cruickshank, M; Moseley, C; Fletcher, S; Albrow, R; Gray, A; Brabin, L; Torgerson, D; Crosbie, E J; Sargent, A; Roberts, C

2018-06-01

Objectives To measure the feasibility and effectiveness of interventions to increase cervical screening uptake amongst young women. Methods A two-phase cluster randomized trial conducted in general practices in the NHS Cervical Screening Programme. In Phase 1, women in practices randomized to intervention due for their first invitation to cervical screening received a pre-invitation leaflet and, separately, access to online booking. In Phase 2, non-attenders at six months were randomized to one of: vaginal self-sample kits sent unrequested or offered; timed appointments; nurse navigator; or the choice between nurse navigator or self-sample kits. Primary outcome was uplift in intervention vs. control practices, at 3 and 12 months post invitation. Results Phase 1 randomized 20,879 women. Neither pre-invitation leaflet nor online booking increased screening uptake by three months (18.8% pre-invitation leaflet vs. 19.2% control and 17.8% online booking vs. 17.2% control). Uptake was higher amongst human papillomavirus vaccinees at three months (OR 2.07, 95% CI 1.69-2.53, p < 0.001). Phase 2 randomized 10,126 non-attenders, with 32-34 clusters for each intervention and 100 clusters as controls. Sending self-sample kits increased uptake at 12 months (OR 1.51, 95% CI 1.20-1.91, p = 0.001), as did timed appointments (OR 1.41, 95% CI 1.14-1.74, p = 0.001). The offer of a nurse navigator, a self-sample kits on request, and choice between timed appointments and nurse navigator were ineffective. Conclusions Amongst non-attenders, self-sample kits sent and timed appointments achieved an uplift in screening over the short term; longer term impact is less certain. Prior human papillomavirus vaccination was associated with increased screening uptake.

A comparison of different strategies used to invite subjects with a positive faecal occult blood test to a colonoscopy assessment. A randomised controlled trial in population-based screening programmes.

Science.gov (United States)

Zorzi, Manuel; Giorgi Rossi, Paolo; Cogo, Carla; Falcini, Fabio; Giorgi, Daniela; Grazzini, Grazia; Mariotti, Loretta; Matarese, Vincenzo; Soppelsa, Fabio; Senore, Carlo; Ferro, Antonio

2014-08-01

The purpose of this parallel randomised controlled trial was to compare compliance with different modalities used to invite patients with a positive immunochemical faecal occult blood test (FIT+) for a total colonoscopy (TC). FIT+ patients from nine Italian colorectal cancer screening programmes were randomised to be invited for a TC initially by mail or by phone and, for non-compliers, to be recalled by mail, for counselling with a general practitioner, or to meet with a specialist screening practitioner (nurse or healthcare assistant). In all, 3777 patients were randomised to different invitation strategies. Compliance with an initial invitation by mail and by phone was similar (86.0% vs. 84.0%, relative risk - RR: 1.02; 95%CI 0.97-1.08). Among non-responders to the initial invitation, compliance with a recall by appointment with a specialist practitioner was 50.4%, significantly higher than with a mail recall (38.1%; RR:1.33; 95%CI 1.01-1.76) or with a face-to-face counselling with the GP (30.8%; RR:1.45;95%CI 1.14-1.87). Compliance with an initial invitation for a TC by mail and by phone was similar. A personal meeting with a specialist screening practitioner was associated with the highest compliance among non-compliers with initial invitations, while the involvement of GPs in this particular activity seemed less effective. Copyright © 2014 Elsevier Inc. All rights reserved.

Gender Differences and Similarities in Receptivity to Sexual Invitations: Effects of Location and Risk Perception.

Science.gov (United States)

Baranowski, Andreas M; Hecht, Heiko

2015-11-01

Since the publication of the seminal paper by Clark and Hatfield (1989), there has been an ongoing discussion about their finding that men accept sexual invitations from females more willingly than vice versa. We focused on two questions that have not yet been answered: First, what happens when the same request for casual sex is made in a different setting where social pressure is lower and such a request more common? To address this issue, 6 male and 8 female average looking confederates approached 162 men and 119 women either at a university campus or in a nightclub and asked for a date or for casual sex. The gender difference remained, with significantly more men than women consenting to a sexual invitation. The second issue concerned the perceived risk for women of accepting such an offer. We made up an elaborate cover story and invited 60 male and female participants into our laboratory. They were shown 10 pictures of persons of the opposite sex and led to believe that these people either consented to date or to have sex with them. The participants then could choose from the pictures who they wanted to meet to engage in a date or sex. In this subjectively safer environment, the gender difference disappeared, with the same proportion of men and women consenting to a date or sex. However, men were more liberal in their choice in either condition, compared to the female subjects. We conclude that while gender differences remained in both experiments, women were more liberal in a subjectively safer situation.

Surgery for adult patients with obstructive sleep apnoea: A review for general practitioners.

Science.gov (United States)

Phan, Nga T; Wallwork, Benjamin; Panizza, Benedict

2016-08-01

Obstructive sleep apnoea (OSA) is a complex disease process that involves collapse of the upper airway during sleep and subsequent reduction or cessation of airflow. Continuous positive airway pressure (CPAP) is the primary treatment for OSA and is the recommended first-line treatment for patients with moderate-to-severe forms of the disease. However, some patients are unable to tolerate CPAP or are unwilling to accept it as a form of permanent management. In these cases, surgical management aimed at addressing anatomical obstruction may be useful and warranted. This article presents an overview of the surgical options available for OSA. The review also describes a useful approach for selecting appropriate patients for surgery. On the basis of an OSA model that accounts for observed increased risk of stroke, cardiovascular disease and motor vehicle accidents, there is evidence to support that surgery is beneficial and cost-effective for patients with severe OSA who are intolerant of CPAP. There are many surgical options available for OSA.

Análisis del éxito de incubación de la tortuga lora (Lepidochelys olivacea) en función del manejo de los nidos. Península de Osa, Costa Rica

OpenAIRE

Malmierca Pérez, Atenea

2018-01-01

En este trabajo de final de grado se expone un análisis del éxito de incubación (éxito de eclosión y éxito de emergencia) de la tortuga lora (Lepidochelys olivacea) en las playas Carate y La Leona (Península de Osa, Costa Rica), según los diferentes métodos de manejo de nidos realizados (nidos in situ, nidos reubicados en playa y nidos reubicados en el vivero). El objetivo principal de este trabajo es ver si tanto el manejo de los nidos, como la temperatura de la arena y el recubrimiento h...

Plateau's problem an invitation to varifold geometry

CERN Document Server

Frederick J Almgren, Jr

2001-01-01

There have been many wonderful developments in the theory of minimal surfaces and geometric measure theory in the past 25 to 30 years. Many of the researchers who have produced these excellent results were inspired by this little book--or by Fred Almgren himself. The book is indeed a delightful invitation to the world of variational geometry. A central topic is Plateau's Problem, which is concerned with surfaces that model the behavior of soap films. When trying to resolve the problem, however, one soon finds that smooth surfaces are insufficient: Varifolds are needed. With varifolds, one can obtain geometrically meaningful solutions without having to know in advance all their possible singularities. This new tool makes possible much exciting new analysis and many new results. Plateau's problem and varifolds live in the world of geometric measure theory, where differential geometry and measure theory combine to solve problems which have variational aspects. The author's hope in writing this book was to encour...

An Invitation to Collaborate: The SPIRIT Open Source Health Care Portal

Science.gov (United States)

Bray, Brian; Molin, Joseph Dal

2001-01-01

The SPIRIT portal is a web site resulting from a joint project of the European Commission 5th Framework Research Programme for Information Society Technologies, Minoru Development (France), Conecta srl (Italy), and Sistema Information Systems (Italy). The portal indexes and disseminates free software, serves as a meeting point for health care informatics researchers, and provides collaboration services to health care innovators. This poster session describes the services of the portal and invites researchers to join a worldwide collaborative community developing evidence based health care solutions.

Association between Obstructive Sleep Apnea and Myocardial Infarction: A Systematic Review

Directory of Open Access Journals (Sweden)

Fernanda Porto

Full Text Available Abstract Obstructive sleep apnea (OSA has been associated to cardiovascular risk factors. However, the association between OSA and cardiovascular disease is still controversial. The objective of the present study was to verify the association between OSA and myocardial infarction (MI. This is a systematic review of the literature performed through electronic data sources MEDLINE/PubMed, PubMed Central, Web of Science and BVS -Biblioteca Virtual em Saúde (Virtual Health Library. The descriptors used were: 'obstructive sleep apnea' AND 'polysomnography' AND 'myocardial infarction' AND 'adults NOT 'treatment.' The present work analysed three prospective studies, selected from 142 articles. The studies followed a total sample of 5,067 OSA patients, mostly composed by male participants. All patients underwent night polysomnography, and all studies found an association between OSA and fatal and non-fatal cardiovascular outcomes. Thus, we were able to observe that 644 (12.7% of the 5,067 patients suffered MI or stroke, or required a revascularization procedure, and 25.6% of these cardiovascular events were fatal. MI was responsible for 29.5% of all 644 analysed outcomes. There is an association between OSA and MI, in male patients, and apnea and hypopnea index (AHI are the most reliable markers.

What do we know about canine osteosarcoma treatment? Review.

Science.gov (United States)

Szewczyk, M; Lechowski, R; Zabielska, K

2015-03-01

Osteosarcoma (OSA) is the most common type of bone tumors in dogs, which has high metastasis ability. 80 % of dogs with OSA die due to lung metastasis. As a result its treatment is a challenge for veterinary practitioners. The authors discuss the etiology, pathogenesis and the possible risk factors of OSA. The article focuses on literature review and the study of recent advances in OSA treatment. The authors describe therapies which have significantly prolonged the lives of dogs, as well as those that have proven to be ineffective. Advantages and disadvantages of limb amputation and limb-sparing surgery have been described. Authors present also the results of both single agent's therapies with the most commonly used drugs as cisplatin, carboplatin and doxorubicin and compare them to the results obtained using combined chemotherapy. The use of nanotechnology as a new approach in OSA treatment in order to avoid multidrug resistance and reduce negative side effects of cytostatic drugs is presented. The main reasons of the therapies failure are also provided in this article.

Influence of rurality, deprivation and distance from clinic on uptake in men invited for abdominal aortic aneurysm screening.

Science.gov (United States)

Crilly, M A; Mundie, A; Bachoo, P; Nimmo, F

2015-07-01

Effective abdominal aortic aneurysm (AAA) screening requires high uptake. The aim was to assess the independent association of screening uptake with rurality, social deprivation, clinic type, distance to clinic and season. Screening across Grampian was undertaken by trained nurses in six community and three hospital clinics. Men aged 65 years were invited for screening by post (with 2 further reminders for non-responders). AAA screening data are stored on a national call-recall database. The Scottish postcode directory was used to allocate to all invited men a deprivation index (Scottish Index of Multiple Deprivation), a Scottish urban/rural category and distance to clinic. Multivariable analysis was undertaken. The cohort included 5645 men invited for screening over 12 months (October 2012 to October 2013); 42·6 per cent lived in urban areas, 38·9 per cent in rural areas and 18·5 per cent in small towns (uptake 87·0, 89·3 and 90·8 per cent respectively). Overall uptake was 88·6 per cent with 76 new AAAs detected: 15·2 (95 per cent c.i. 11·8 to 18·6) per 1000 men screened. Aberdeen city (large urban area) had the lowest uptake (86·1 per cent). Uptake declined with increasing deprivation, with the steepest decline in urban areas. On multivariable analysis, a 1-point increase in deprivation deciles was associated with a 0·08 (95 per cent c.i. 0·06 to 0·11) reduction in the odds of being screened (P < 0·001). Clinic type (community versus hospital), distance to clinic and season were not associated independently with uptake. Both urban residence and social deprivation were associated independently with uptake among men invited for AAA screening. © 2015 BJS Society Ltd Published by John Wiley & Sons Ltd.

76 FR 79764 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel DREAM CATCHER; Invitation for...

Science.gov (United States)

2011-12-22

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0156] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel DREAM CATCHER; Invitation for Public Comments AGENCY... DREAM CATCHER is: INTENDED COMMERCIAL USE OF VESSEL: ``Passenger charter.'' GEOGRAPHIC REGION: ``Georgia...

78 FR 19066 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel MI CASA; Invitation for...

Science.gov (United States)

2013-03-28

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0035] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel MI CASA; Invitation for Public Comments AGENCY... CASA is: Intended Commercial Use of Vessel: Passenger charters. Geographic Region: Massachusetts, New...

77 FR 35743 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SECOND CHANCE; Invitation for...

Science.gov (United States)

2012-06-14

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2012 0067] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SECOND CHANCE; Invitation for Public Comments AGENCY... SECOND CHANCE is: Intended Commercial Use of Vessel: ``Small group charters.'' Geographic Region...

78 FR 77200 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel AFFAIR; Invitation for Public...

Science.gov (United States)

2013-12-20

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013-0151] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel AFFAIR; Invitation for Public Comments AGENCY: Maritime... AFFAIR is: Intended Commercial Use of Vessel: ``Charter Fishing (sport) & sightseeing tours.'' Geographic...

77 FR 20100 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel NORDIC STAR; Invitation for...

Science.gov (United States)

2012-04-03

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2012 0039] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel NORDIC STAR; Invitation for Public Comments AGENCY... NORDIC STAR is: Intended Commercial Use of Vessel: ``Sailing excursions and extended charters...

How to assess, diagnose, refer and treat adult obstructive sleep apnoea: a commentary on the choices.

Science.gov (United States)

Mansfield, Darren R; Antic, Nicholas A; McEvoy, R Doug

2013-10-21

Obstructive sleep apnoea (OSA) determined by polysomnography is highly prevalent, affecting about 25% of men and 10% of women in the United States, although most have few or no symptoms. Symptomatic moderate to severe OSA has major health implications related to daytime sleepiness, such as increased accidents, altered mood and loss of productivity in the workplace. Severe OSA may increase the risk of cardiovascular disease independent of daytime sleepiness. A major challenge is to correctly identify, from the large community pool of disease, people with symptoms and those at risk of long-term complications. For treatment plans to achieve quality patient outcomes, clinicians must have a clear understanding of patients' symptoms and their motivations for presentation, and be knowledgeable about the evidence surrounding the health risks of OSA and the relative merits of the various diagnostic and treatment options available. The diagnosis of OSA represents a teachable moment to target adverse lifestyle factors such as excessive weight, excessive alcohol consumption and smoking, which may be contributing to OSA and long-term cardiometabolic risk. OSA assessment and management has traditionally involved specialist referral and in-laboratory polysomnography. However, these services may not always be easy to access. Controlled studies have shown that patients with a high pretest probability of symptomatic, moderate to severe OSA can be managed well in primary care, or by skilled nurses with appropriate medical backup, using simplified ambulatory models of care. The future of sleep apnoea assessment and management will likely include models of care that involve early referral to specialists of patients with complex or atypical presentations, and an upskilled and supported primary care workforce to manage symptomatic, uncomplicated, high pretest probability disease.

Oropharyngeal Dysphagia in patients with obstructive sleep apnea syndrome.

Science.gov (United States)

Schindler, Antonio; Mozzanica, Francesco; Sonzini, Giulia; Plebani, Daniela; Urbani, Emanuele; Pecis, Marica; Montano, Nicola

2014-02-01

Although previous studies demonstrated that patients with obstructive sleep apnea syndrome (OSAS) may present subclinical manifestations of dysphagia, in not one were different textures and volumes systematically studied. The aim of this study was to analyze the signs and symptoms of oropharyngeal dysphagia using fiberoptic endoscopic evaluation of swallowing (FEES) with boluses of different textures and volumes in a large cohort of patients with OSAS. A total of 72 OSAS patients without symptoms of dysphagia were enrolled. The cohort was divided in two groups: 30 patients with moderate OSAS and 42 patients with severe OSAS. Each patient underwent a FEES examination using 5, 10 and 20 ml of liquids and semisolids, and solids. Spillage, penetration, aspiration, retention, and piecemeal deglutition were considered. The penetration-aspiration scale (PAS), pooling score (PS), and dysphagia outcome and severity scale (DOSS) were used for quantitative analysis. Each patient completed the SWAL-QOL questionnaire. Forty-six patients (64 %) presented spillage, 20 (28 %) piecemeal deglutition, 26 (36 %) penetration, and 30 (44 %) retention. No differences were found in the PAS, PS, and DOSS scores between patients with moderate and severe OSAS. Patients with severe OSAS scored higher General Burden and Food selection subscales of the SWAL-QOL. Depending on the DOSS score, the cohort of patients was divided into those with and those without signs of dysphagia. Patients with signs of dysphagia scored lower in the General Burden and Symptoms subscales of the SWAL-QOL. OSAS patients show signs of swallowing impairment in about half of the population; clinicians involved in the management of these patients should include questions on swallowing when taking the medical history.

Perioperative management of obstructive sleep apnea: a survey of Veterans Affairs health care providers.

Science.gov (United States)

Dhanda Patil, Reena; Patil, Yash J

2012-01-01

(1) To determine the presence of Veterans Affairs (VA) institutional guidelines for the perioperative management of obstructive sleep apnea (OSA); (2) to examine current use of preoperative screening tools for OSA in the VA; and (3) to understand current VA practice patterns regarding postoperative disposition of patients with OSA. Survey study. Veterans Affairs hospitals with surgical services; sample size 102 facilities. Veterans Affairs health care providers. The authors surveyed health care providers at VA hospitals using a survey tool developed by the authors. The response rate was 80%. A variety of preoperative screening tools for OSA were used by respondents, most commonly American Society of Anesthesiologists guidelines (53%). A policy for postoperative disposition of known and presumed OSA was present in 26% and 19% of responses, respectively. Of those respondents reporting a formal postoperative care policy, 48% and 30% admitted patients to a monitored ward bed and surgical intensive care unit, respectively. Of the 74% of respondents unaware of an institutional policy, Anesthesia and Surgery worked together to dictate postoperative disposition of patients with known OSA 73% of the time. The degree of OSA was ranked as the most important factor (58%) influencing postoperative disposition. Ten percent of respondents reported a major perioperative complication attributable to OSA in the past year. This survey study elucidates the heterogeneity of preoperative screening for and postoperative care of veterans with OSA. Future investigators may use these data to formalize institutional policies with regard to patients with OSA, with potentially significant impacts on patient care and usage of financial resources.

El Trabajo Comunitario en la Comunidad Montañosa de Jibacoa: Acciones de Recreación Física y Cultura Artística y Literaria

Directory of Open Access Journals (Sweden)

Javier Rodríguez Galindo

2009-12-01

Full Text Available En nuestro país, Cuba, se brinda gran atención al mejoramiento de la calidad de vida de los habitantes de las comunidades ubicadas en los cuatros macizos montañosos a través del Programa de montaña conocido como Plan Turquino; específicamente en nuestra provincia se ha logrado resultados significativos en los programas socio- culturales dirigidos a tales fines. Nuestra investigación se ha encaminado al estudio de la Recreación Física y la Cultura Artística y Literaria en la comunidad montañosa de Jibacoa. Las bases que nos antecedieron sobre esta temática nos muestra las insuficiencias en la integración entre los profesionales de la cultura física, promotores culturales y otros gestores del trabajo comunitario en la realización de las actividades recreativas y artísticas, la poca diversidad de las propuestas que se ofertan a la población, en especial a niñas y niños, insuficiente aprovechamiento del medio natural para la realización de las actividades, así como por las exigencias actuales de brindarles a las niñas y niños opciones recreativas en vistas del logro de una cultura general integral. Para llevar a cabo todo un proceso de recopilación de información se han aplicado diferentes métodos como: observación, encuestas, así como la aplicación de diferentes técnicas grupales, las cuales nos permitieron conocer el estado actual de la recreación en la comunidad montañosa de Jibacoa, enfatizando en la presencia de elementos físicos recreativos y artísticos y literarios. Dicha constatación nos colocan en la propuesta de un plan de acciones en correspondencias con los gustos y preferencias de las niñas y niños de la comunidad en estudio, la cual después de ser validada por parte del Grupo de Trabajo y otros Evaluadores Externos se llevo a la Práctica, logrando los criterio por parte de la comunidad, para estar en condiciones de una nueva planificación.

78 FR 35091 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BAD INFLUENCE; Invitation for...

Science.gov (United States)

2013-06-11

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0072] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BAD INFLUENCE; Invitation for Public Comments AGENCY....gov . SUPPLEMENTARY INFORMATION: As described by the applicant the intended service of the vessel BAD...

77 FR 26818 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel FREE SPIRIT; Invitation for...

Science.gov (United States)

2012-05-07

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2012-0058] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel FREE SPIRIT; Invitation for Public Comments AGENCY... SPIRIT is: Intended Commercial Use of Vessel: ``Day/overnight passenger passage. Depart and return same...

78 FR 42153 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel COMPASS ROSE; Invitation for...

Science.gov (United States)

2013-07-15

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013-0081] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel COMPASS ROSE; Invitation for Public Comments AGENCY... COMPASS ROSE is: Intended Commercial Use Of Vessel: ``Sailboat charters six passengers or less...

77 FR 16582 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel KAMI KAY; Invitation for...

Science.gov (United States)

2012-03-21

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2012-0033] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel KAMI KAY; Invitation for Public Comments AGENCY....gov . SUPPLEMENTARY INFORMATION: As described by the applicant the intended service of the vessel KAMI...

77 FR 58213 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel ISLAND WATERS; Invitation for...

Science.gov (United States)

2012-09-19

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2012 0095] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel ISLAND WATERS; Invitation for Public Comments AGENCY... ISLAND WATERS is: Intended Commercial Use of Vessel: ``Charter to individuals in coastal waters...

78 FR 8698 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel COOL BEANS; Invitation for...

Science.gov (United States)

2013-02-06

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0005] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel COOL BEANS; Invitation for Public Comments AGENCY... BEANS is: Intended Commercial Use of Vessel: Sightseeing and sunset cruises. Geographic Region: Florida...

78 FR 35092 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BEAR BOAT; Invitation for...

Science.gov (United States)

2013-06-11

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013-0069] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BEAR BOAT; Invitation for Public Comments AGENCY....gov . SUPPLEMENTARY INFORMATION: As described by the applicant the intended service of the vessel BEAR...

76 FR 67253 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel THE GIFT; Invitation for...

Science.gov (United States)

2011-10-31

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2011 0131] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel THE GIFT; Invitation for Public Comments AGENCY... GIFT is: INTENDED COMMERCIAL USE OF VESSEL: ``Passenger carrying.'' GEOGRAPHIC REGION: ``ME, NH, MA, RI...

76 FR 70216 - Requested Administrative Waiver of the Coastwise Trade Laws; Vessel REEL ATTITUDE; Invitation for...

Science.gov (United States)

2011-11-10

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011 0146] Requested Administrative Waiver of the Coastwise Trade Laws; Vessel REEL ATTITUDE; Invitation for Public Comments AGENCY... ATTITUDE is: Intended Commercial Use of Vessel: ``Fishing Charter passenger less than 6.'' Geographic...

Fate of oil-SPM aggregates in the St-Lawrence estuary

International Nuclear Information System (INIS)

Khelifa, A.; Brown, C.

2009-01-01

The formation of aggregates of oil-suspended particulate matter (SPM) has been studied extensively over the last 4 decades. This paper presented the results of a full scale numerical study that examined the fate of oil-SPM aggregates (OSAs) formed in the St-Lawrence estuary in both shallow and deep water. OSAs form from the natural heteroaggregation between suspended oil droplets and SPM following an oil spill in the aquatic environment. Until recently, it was believed that this natural process helps clean oiled shorelines by dispersing spilled oil in coastal waters rich in SPM. However, new studies have shown that the density of OSAs may exceed the density of the seawater and their formation may result in the transfer of considerable amounts of oil from the water column to the seafloor. This study was conducted using real hydrodynamic data, recent laboratory data related to the size, density and oil content of OSAs and the commercial CHEMMAP software. Simulations were run for 5 days for each scenario. The concentrations of OSAs in the water column and on the seafloor were tracked in space and time. According to the results, the size and density of OSAs have a strong influence on the fate of OSAs, as do water depth and current density. OSAs of 200 μm in size and higher settled within half a day in shallow water zones, and within 5 days in deep water zones. The resulting oil concentration in bottom sediment showed strong increase with the size of OSA in shallow water, but small increase in deep water. Sedimentation of OSAs with an average size of 200 μm is affected by the effective density. In general, horizontal mixing had a much smaller effect on the sedimentation of OSAs than those obtained with their size and effective density. It was concluded that ideally, the fate of OSAs should be addressed using a dynamic model that relates the size of OSAs to local intensity of turbulence. 20 refs., 1 tab., 10 figs.

Changes of plasma ADM and ANP of pulmonary artery hypertension in patients with obstructive sleep apnea syndrome

International Nuclear Information System (INIS)

Gao Zhi; Zhong Jian; Sheng Chunyong; Xu Shouhong

2005-01-01

Objective: To explore the incidence of pulmonary artery hypertension (PAH) and changes of plasma adrenomedullin (ADM) and atrial natriuretic polypeptide (ANP) in patients with obstructive sleep apnea syndrome (OSAS). Methods: 32 healthy middle- and elder-aged cases were randomly selected as control group, 61 cases were confirmed clinically with OSAS. The pressure of pulmonary artery was measured with real time gray scale two-dimensional ultrasonic tomography, the blood plasma levels of ADM and ANP were determined with radioimmunoassay method. Results: Among 61 OSAS patients, 26 of them presented with PAH, its incidence in OSAS was 42.6%. The plasma level of ADM in OSAS with non-PAH group had statistical difference compared with control group ( P < 0.05 ) , also there were significant differences between PAH, non-PAH and control group (P<0.001). Concurrently, the plasma level of ANP in OSAS with PAH, non-PAH also had significant differences compared with control group (P<0.001). Conclusions: There was high incidence of PAH in OSAS patients. The plasma levels of ADM and ANP positively correlated with PAH. ANP played a role in the pathophysiologic genesis of PAH. (authors)

Sleep apnea syndrome and cognition

Directory of Open Access Journals (Sweden)

Emilia eSforza

2012-05-01

Full Text Available Obstructive sleep apnea (OSA is a sleep-related breathing disorder characterized by repetitive episodes of airflow cessation resulting in brief arousals and intermittent hypoxemia. Several studies have documented significant daytime cognitive and behavioral dysfunction that seems to extend beyond that associated with simple sleepiness and that persists in some patients after therapeutic intervention. A still unanswered question is whether cognitive symptoms in OSA are primarily a consequence of sleep fragmentation and hypoxemia, or whether they coexist independently from OSA. Moreover, very little is known about OSA effects on cognitive performances in the elderly in whom an increased prevalence of OSA is present.In this review we will consider recent reports in the association between sleep apnea and cognition, with specific interest in elderly subjects, in whom sleep disturbances and age-related cognitive decline naturally occur. This will allow us to elucidate the behavioral and cognitive functions in OSA patients and to gain insight into age differences in the cognitive impairment.Clinically, these outcomes will aid clinicians in the evaluation of diurnal consequences of OSA and the need to propose early treatment.

Chronic intermittent hypoxia and obstructive sleep apnea: an experimental and clinical approach

Science.gov (United States)

Sforza, Emilia; Roche, Fréderic

2016-01-01

Obstructive sleep apnea (OSA) is a prevalent sleep disorder considered as an independent risk factor for cardiovascular consequences, such as systemic arterial hypertension, ischemic heart disease, cardiac arrhythmias, metabolic disorders, and cognitive dysfunction. The pathogenesis of OSA-related consequence is assumed to be chronic intermittent hypoxia (IH) inducing alterations at the molecular level, oxidative stress, persistent systemic inflammation, oxygen sensor activation, and increase of sympathetic activity. Overall, these mechanisms have an effect on vessel permeability and are considered to be important factors for explaining vascular, metabolic, and cognitive OSA-related consequences. The present review attempts to examine together the research paradigms and clinical studies on the effect of acute and chronic IH and the potential link with OSA. We firstly describe the literature data on the mechanisms activated by acute and chronic IH at the experimental level, which are very helpful and beneficial to explaining OSA consequences. Then, we describe in detail the effect of IH in patients with OSA that we can consider “the human model” of chronic IH. In this way, we can better understand the specific pathophysiological mechanisms proposed to explain the consequences of IH in OSA. PMID:27800512

Elevated Plasma Levels of Soluble (Pro)Renin Receptor in Patients with Obstructive Sleep Apnea Syndrome in Parallel with the Disease Severity.

Science.gov (United States)

Nishijima, Tsuguo; Tajima, Kazuki; Yamashiro, Yoshihiro; Hosokawa, Keisuke; Suwabe, Akira; Takahashi, Kazuhiro; Sakurai, Shigeru

2016-04-01

(Pro)renin receptor ((P)RR), a receptor for renin and prorenin, is implicated in the pathophysiology of diabetes mellitus, hypertension and their complications. Soluble (P)RR (s(P)RR) is composed of extracellular domain of (P)RR and thus exists in blood. We have reported that plasma concentrations of s(P)RR were elevated in male patients with obstructive sleep apnea syndrome (OSAS). The aim of the present study was to clarify the difference in plasma s(P)RR concentrations between male and female OSAS patients. Plasma s(P)RR concentrations were studied in 289 subjects (206 males and 83 females) consisting of 259 OSAS patients and 30 non-OSAS control subjects. The 259 OSAS patients were classified into mild (5 ≤ apnea hypopnea index (AHI) value found in male subjects (male r = 0.413, p < 0.0001; female r = 0.263, p < 0.05). Importantly, when OSAS patients (26 males and 15 females) with AHI ≥ 20 underwent continuous positive airway pressure treatment, plasma s(P)RR levels were significantly decreased. In conclusion, plasma s(P)RR levels are elevated in both male and female OSAS patients in parallel with the disease severity.

Management of Obstructive Sleep Apnea

Directory of Open Access Journals (Sweden)

V K Vijayan

2014-03-01

Full Text Available Obstructive Sleep Apnea (OSA is an important public health problem and is associatedwith considerable morbidity and mortality. Therefore, treatment of this condition is ofparamount importance. The treatment of OSA includes general and behaviouralmeasures, mechanical measures including continuous positive airway pressure(CPAP, Bilevel positive airway pressure (BiPAP and Oral Appliances (OA,pharmacological treatment and surgical procedures. Continuous positive airwaypressure (CPAP treatment reverses the repetitive upper airway obstruction of sleepapnea and associated daytime sleepiness and is the most effective treatment for OSA.However maintaining patient adherence to CPAP therapy is a challenge. Weight lossshould be recommended to overweight patients with OSA, as it has been shown thatweight reduction has additional health benefits. Treatment of underlying medicalconditions such as hypothyroidism or acromegaly has profound effect onapnea/hypopnea index. A subset of patients with OSA may benefit from supplementaloxygen and positional therapy. Presently, there are no effective pharmacotherapeuticagents for treatment of patients with OSA and the role of surgical treatment in OSA iscontroversial. However, pharmacological treatment of persisting residual sleepiness,despite adequate positive airway pressure therapy delivery and adherence, is indicatedand may improve daytime sleepiness.Key words : CPAP, Oral appliances, Modafinil, CPAP complianceUvulopalatopharyngoplasty, positional therapy

Desenvolvimento dos frutos de lulo (Solanum quitoense LAM, em Viçosa-MG

Directory of Open Access Journals (Sweden)

Pedro Henrique Monteiro Matarazzo

2013-03-01

Full Text Available O lulo é um fruto tropical e exótico, originário dos Andes, tem cor laranja quando maduro, e é uma baga globosa, assemelha- se a um tomate, o epicarpo é grosso e coriáceo, sua polpa é verde-clara, pegajosa, ácida e suculenta, contendo muitas sementes. Objetivou-se acompanhar as características físicas, químicas e fisiológicas ocorridas durante o desenvolvimento do fruto de lulo, da antese ao amadurecimento completo, em Viçosa-MG. Os frutos apresentaram um padrão de crescimento sigmoidal simples em resposta à variação do tempo. O desenvolvimento do fruto foi dividido em três fases. A primeira foi até os 7,39 dias após a antese (DAA, sendo caracterizada pela alta taxa respiratória, provavelmente devido à intensa multiplicação celular, e o pericarpo apresentava coloração verde-clara. A segunda fase estendeu-se a partir dos 7,39 até os 57,63 DAA, sendo caracterizada pelas taxas máximas das características estudadas. A taxa respiratória cresceu até 45 DAA, mantendo-se estável até os 52 DAA. A última fase estendeu-se a partir dos 57,63 DAA até os 95,00 DAA. Essa fase foi caracterizada pela estabilização nas dimensões e no acúmulo de massa fresca. Nesse período, ocorreu a ascensão climatérica (dos 52 aos 59 DAA. O climatério respiratório ocorreu aos 66 DAA, com pico de produção de CO2 de 110,99 mg de CO2 kg-1h-1. O pós-climatério ocorreu dos 73 aos 95 DAA, quando houve aumento no teor de sólidos solúveis e queda da acidez titulável e vitamina C da polpa. Nessa fase, o pericarpo dos frutos apresentava-se com coloração alaranjada.

Who uses NHS health checks? Investigating the impact of ethnicity and gender and method of invitation on uptake of NHS health checks.

Science.gov (United States)

Cook, Erica J; Sharp, Chloe; Randhawa, Gurch; Guppy, Andy; Gangotra, Raj; Cox, Jonathon

2016-01-20

NHS Health Checks is a national risk assessment prevention programme for all individuals aged 40-74 that reside in England. Through the systematic assessment of an individual's ten year disease risk, this programme aims to provide early identification and subsequent management of this risk. However, there is limited evidence on how socio-demographic factors impact on uptake and what influence the invitation method has on uptake to this programme. NHS Health Check data from April 2013 to March 2014 was analysed (N = 50,485) for all 30 GP Practices in Luton, a culturally diverse town in England, UK. Data was collected for age, ethnicity, uptake (attendance and non attendance) and invitation method (letter written, verbal face-to-face, telephone). Actual usage of NHS Health Checks was determined for each ethnic group of the population and compared using Chi-square analysis. The overall uptake rate for Luton was 44 %, markedly lower that the set target of 50-75 %. The findings revealed a variation of uptake in relation to age, gender, level of deprivation. Ethnicity and gender variations were also found, with 'White British' 'Black Caribbean' and 'Indian' patients most likely to take up a NHS Health Check. However, patients from 'Any Other White Background' and 'Black African' were significantly less likely to uptake an NHS Health Check compared to all other ethnic groups. Ethnicity and gender differences were also noted in relation to invitation method. The findings revealed that different invitation methods were effective for different ethnic and gender groups. Therefore, it is suggested that established protocols of invitation are specifically designed for maximizing the response rate for each population group. Future research should now focus on uncovering the barriers to uptake in particular culturally diverse population groups to determine how public health teams can better engage with these communities.

77 FR 26819 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BLUE PLANET; Invitation for...

Science.gov (United States)

2012-05-07

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2012-0054] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BLUE PLANET; Invitation for Public Comments AGENCY... PLANET is: Intended Commercial use of Vessel: ``Charter to Boy Scouts of America Florida Sea Base...

78 FR 25530 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BLUE DOLPHIN; Invitation for...

Science.gov (United States)

2013-05-01

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013-0049] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BLUE DOLPHIN; Invitation for Public Comments AGENCY... DOLPHIN is: Intended Commercial Use Of Vessel: ``Skippered daysailing in Puget Sound and San Juan Islands...

78 FR 13752 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SPIRIT; Invitation for Public...

Science.gov (United States)

2013-02-28

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0013] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SPIRIT; Invitation for Public Comments AGENCY: Maritime... . SUPPLEMENTARY INFORMATION: As described by the applicant the intended service of the vessel SPIRIT is: Intended...

77 FR 22631 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SPIRIT; Invitation for Public...

Science.gov (United States)

2012-04-16

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2012 0049] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SPIRIT; Invitation for Public Comments AGENCY: Maritime... . SUPPLEMENTARY INFORMATION: As described by the applicant the intended service of the vessel SPIRIT is: Intended...

76 FR 67255 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel KIWI CAT; Invitation for...

Science.gov (United States)

2011-10-31

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2011 0135] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel KIWI CAT; Invitation for Public Comments AGENCY... CAT is: INTENDED COMMERCIAL USE OF VESSEL: ``Small vessel 12 person chartering service for the San...

76 FR 76812 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BARBARY GHOST; Invitation for...

Science.gov (United States)

2011-12-08

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2011 0148] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BARBARY GHOST; Invitation for Public Comments AGENCY... BARBARY GHOST is: Intended Commercial Use Of Vessel: ``Sightseeing tours in the San Francisco Bay for a...

78 FR 30961 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel LITTLE DUTCH; Invitation for...

Science.gov (United States)

2013-05-23

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013-0057] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel LITTLE DUTCH; Invitation for Public Comments AGENCY... LITTLE DUTCH is: Intended Commercial Use of Vessel: ``Carrying up to six passengers for day trips, sunset...

Increasing Partner Attendance in Antenatal Care and HIV Testing Services: Comparable Outcomes Using Written versus Verbal Invitations in an Urban Facility-Based Controlled Intervention Trial in Mbeya, Tanzania.

Directory of Open Access Journals (Sweden)

Stefanie Theuring

Full Text Available In many Sub-Saharan African settings male partner involvement in antenatal care (ANC remains low, although great benefits for maternal and infant health outcomes have been long recognised, in particular regarding the prevention of HIV transmission. Yet there is paucity on evidence regarding the effectiveness of strategies to increase male partner involvement. This controlled intervention trial in Ruanda Health Centre in Mbeya, Tanzania, assessed the effectiveness of invitation letters for male involvement in ANC. Pregnant women approaching ANC without partners received official letters inviting the partner to attend ANC. A control group was instructed to verbally invite partners. Partner attendance was recorded at two subsequent ANC visits. Rates for male partner return, couple voluntary counselling and testing (CVCT, and influencing factors were analysed. From 199 ANC clients in total, 97 were assigned to the invitation letter group; 30 of these (30.9% returned with their male partners for ANC. In the control group of 102 women, 28 (27.5% returned with their partner. In both groups CVCT rates among jointly returning couples were 100%. Partner return/CVCT rate was not statistically different in intervention and control group (OR 1.2, p = 0.59. Former partner attendance at ANC during a previous pregnancy was the only factor found to be significantly linked with partner return (p = 0.03. Our study demonstrates that rather simple measures to increase male partner attendance in ANC and CVCT can be effective, with written and verbal invitations having comparable outcomes. In terms of practicability in Sub-Saharan African settings, we recommend systematic coaching of ANC clients on how to verbally invite male partners in the first instance, followed by written invitation letters for partners in case of their non-attendance. Further studies covering both urban and rural settings will be more informative for effective translation into policy.

Obstructive Sleep Apnea: An Unusual Cause of Hemorrhagic Stroke.

Science.gov (United States)

Pawar, Nilesh H; O'Riordan, Jennifer A; Malik, Preeti; Vasanwala, Farhad F

2017-09-27

Stroke is one of the most common causes of mortality and morbidity worldwide. Hemorrhagic stroke comprises 10-20% of strokes. Here, we present a case report of hemorrhagic stroke that may have been secondary to untreated Obstructive Sleep Apnea (OSA) in a young man with no other cardiovascular risk factors or features of metabolic syndrome. A 32-year-old man was admitted for hemorrhagic stroke. An initial thorough workup for the etiology of stroke was inconclusive. Eventually, a polysomnography was done, which demonstrated OSA suggesting that untreated OSA may have contributed to his stroke. OSA may cause hemorrhagic stroke by nocturnal blood pressure surge. So, all physicians should consider doing polysomnography for unexplained hemorrhagic stroke or in patients at risk. Diagnosing and treating OSA would be critical in preventing hemorrhagic stroke and its recurrences.

Pharyngeal chemosensitivity in patients with obstructive sleep apnea and healthy subjects.

Science.gov (United States)

Heiser, Clemens; Zimmermann, Ingo; Sommer, J Ulrich; Hörmann, Karl; Herr, Raphael M; Stuck, Boris A

2013-09-01

Signs of pharyngeal neurodegeneration have been detected in patients with obstructive sleep apnea (OSA). Along with this neurodegeneration, a decreased pharyngeal sensitivity to mechanical stimulation has been described. The decreased sensitivity may play a role in the pathophysiology of this disease. The aim of the study was to investigate the chemosensitivity of the pharyngeal mucosa in patients with OSA compared with controls. Healthy controls and patients with OSA (age: 30-60 years) were included. Testing of oropharyngeal chemosensitivity was performed with subjective intensity ratings of capsaicin (SIR, visual analogue scale 0-10), air puffs (presented with an olfactometer), and stimulation with CO2 at the posterior pharyngeal wall. A 2-point discrimination test at the soft palate, an intensity rating of capsaicin at the tongue, and a nasal lateralization test were performed. Twenty-six patients with OSA and 18 healthy controls were included. No differences were detected in the SIR of capsaicin at the tongue or in the nasal lateralization test. At the pharynx, a decreased sensitivity to capsaicin (OSA: 6.8 ± 2.3; healthy control: 8.6 ± 1.3), air puffs (OSA: 2.8 ± 1.9; healthy control: 4.2 ± 1.6), and stimulation with CO2 (OSA: 1.5 ± 1.7; healthy control: 2.8 ± 1.8) were demonstrated in patients with OSA (all P < 0.05). Two-point discrimination at the soft palate was reduced with statistical significance in the OSA group (OSA: 11.5 ± 5.4 mm; healthy control: 5.0 ± 2.4 mm). The results suggest reduced pharyngeal chemosensitivity in OSA patients in addition to the reduced mechanical pharyngeal sensitivity shown with 2-point discrimination. This demonstrates peripheral neurodegeneration in the context of this disease.

78 FR 33149 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel CATTITUDE; Invitation for...

Science.gov (United States)

2013-06-03

... Administrative Waiver of the Coastwise Trade Laws: Vessel CATTITUDE; Invitation for Public Comments AGENCY... Floor, Room W12-140, 1200 New Jersey Avenue SE., Washington, DC 20590. You may also send comments electronically via the Internet at http://www.regulations.gov . All comments will become part of this docket and...

A brief review of nuclear electronics standards . . . Past, present and future

International Nuclear Information System (INIS)

Larsen, R.S.

2000-01-01

Modular Nuclear Instrument Standards have played a key role in U. S. Department of Energy National Laboratories and similar scientific laboratories worldwide for more than three decades. The scientific and engineering efficiency and economic benefits have been well documented. Standards are constantly evolving with the introduction of new technologies and the present is a time of rapid change. This report is based on an invited talk presented at the Joint Meeting of the U.S. Nuclear Instrument Module (NIM) and European Standards for Norms in Electronics (ESONE) Standards Committees, Lyon, France, October 20, 2000. It provides a brief overview of past developments and attempts to identify areas of possible opportunities for renewed standardization efforts to meet future challenges

Data Collection, Access and Presentation Technologies in the National Ecological Observatory (NEON) Design (Invited)

Science.gov (United States)

Aulenbach, S. M.; Berukoff, S. J.

2010-12-01

The National Ecological Observatory Network (NEON) will collect data across the United States on the impacts of climate change, land use change and invasive species on ecosystem functions and biodiversity. In-situ sampling and distributed sensor networks, linked by an advanced cyberinfrastructure, will collect site-based data on a variety of organisms, soils, aquatic systems, atmosphere and climate. Targeted airborne remote sensing observations made by NEON as well as geographical data sets and satellite resources produced by Federal agencies will provide data at regional and national scales. The resulting data streams, collected over a 30-year period, will be synthesized into fully traceable information products that are freely and openly accessible to all users. We provide an overview of several collection, access and presentation technologies evaluated for use by observatory systems throughout the data product life cycle. Specifically, we discuss smart phone applications for citizen scientists as well as the use of handheld devices for sample collection and reporting from the field. Protocols for storing, queuing, and retrieving data from observatory sites located throughout the nation are highlighted as are the application of standards throughout the pipelined production of data products. We discuss the automated incorporation of provenance information and digital object identifiers for published data products. The use of widgets and personalized user portals for the discovery and dissemination of NEON data products are also presented.

Increased cell-free DNA concentrations in patients with obstructive sleep apnea.

Science.gov (United States)

Shin, Chol; Kim, Jin K; Kim, Je H; Jung, Ki H; Cho, Kyung J; Lee, Chang K; Lee, Seung G

2008-12-01

Blood concentrations of cell-free DNA, which is considered to be released during apoptosis, are elevated under some pathological conditions such as cardiovascular disease and cancer. The association between obstructive sleep apnea (OSA) and cell-free DNA concentrations has not been reported so far. The purpose of the present study was to examine the association between OSA and plasma DNA concentrations. A case-control study was conducted using a total of 164 men aged 39-67 years, who were free of coronary heart disease and cancer. Laboratory-based overnight polysomnography was performed for all participants. On the basis of polysomnography, patients with an apnea-hypopnea index (AHI) = 5-30 events/h were defined as having mild-moderate OSA (n = 33) and those with >30 events/h were defined as having severe OSA (n = 49). All 82 controls had AHI DNA concentrations from all participants were analyzed for the beta-globin gene using fluorescence-based real-time polymerase chain reaction. Patients with severe OSA had significantly higher plasma DNA concentrations than persons with mild-moderate OSA and those without OSA (P DNA concentration (P DNA concentrations (>8 microg/L) had approximately fourfold higher odds of OSA than those with low DNA levels. Further data are warranted to confirm the association for men and to evaluate the association for women.

Sensory analysis and volatile compounds of olive oil (cv. Cobrançosa from different irrigation regimes

Directory of Open Access Journals (Sweden)

Fernandes-Silva, A. A.

2013-03-01

Full Text Available The aim of this study was to assess the effect of different irrigation strategies on the sensory quality of virgin olive oil (VOO from the cv. “cobrançosa” integrated into a protected denomination of origin of “Azeite de Trás-os-Montes” in the Northeast of Portugal. Three irrigation treatments were applied: (T2-full irrigation, which received a seasonal water equivalent of 100% of the estimated crop evapotranspiration (ET_c, (T1-continuous deficit irrigation (30% ET_c and (T0- rainfed treatment. Data were collected from two consecutive crop years (2005-2006. Olive oil samples were analyzed for volatiles by GC-MS and the results compared with sensory evaluation data. Total volatile compounds tended to decrease with the amount of water applied. The characteristics pungent and bitter were more pronounced in olive oils from T0 and T1, which had higher polyphenolic concentrations, with a strong positive relationship with this variable and the bitter attribute. The Principal Components Analysis clearly separates the three olive oils from 2005, the driest year, and aggregates into a single group the three samples from 2006, suggesting no effect of irrigation on volatile compounds in years with a rainy spring and a marked effect in years with severe drought, suggesting that the effect of the trees’ water status on these variables occurs throughout the crop season and not just during the oil accumulation phase. In general, olive oil from the cv. Cobrançosa is more bitter than pungent and has a typical nutty sensory attribute shown by a strong positive relationship between benzaldehyde and the sensory notes of almonds and nuts.

Este estudio tiene como objetivo evaluar el efecto de distintas estrategias de riego en la composición relativa de los compuestos volátiles y en la calidad sensorial. El experimento se realizó en el Noreste de Portugal, dentro de la denominación de origen protegida “Azeites de Tr

77 FR 37948 - Free Trade Agreements; Invitation for Applications for Inclusion on Dispute Settlement Lists for...

Science.gov (United States)

2012-06-25

..., Colombia, Korea, Morocco, and Singapore AGENCY: Office of the United States Trade Representative (``USTR...-Singapore Free Trade Agreement (``USSFTA''). USTR is inviting interested persons to apply to be on one or...-9483 to arrange for an alternative method of transmission. FOR FURTHER INFORMATION CONTACT: For...

77 FR 5628 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BIG GAME; Invitation for...

Science.gov (United States)

2012-02-03

... Administrative Waiver of the Coastwise Trade Laws: Vessel BIG GAME; Invitation for Public Comments AGENCY....gov . SUPPLEMENTARY INFORMATION: As described by the applicant the intended service of the vessel BIG GAME is: Intended Commercial Use of Vessel: ``Fishing charter boat.'' Geographic Region: ``Rhode Island...

Nonlinear Dynamics Forecasting of Obstructive Sleep Apnea Onsets.

Directory of Open Access Journals (Sweden)

Trung Q Le

Full Text Available Recent advances in sensor technologies and predictive analytics are fueling the growth in point-of-care (POC therapies for obstructive sleep apnea (OSA and other sleep disorders. The effectiveness of POC therapies can be enhanced by providing personalized and real-time prediction of OSA episode onsets. Previous attempts at OSA prediction are limited to capturing the nonlinear, nonstationary dynamics of the underlying physiological processes. This paper reports an investigation into heart rate dynamics aiming to predict in real time the onsets of OSA episode before the clinical symptoms appear. A prognosis method based on a nonparametric statistical Dirichlet-Process Mixture-Gaussian-Process (DPMG model to estimate the transition from normal states to an anomalous (apnea state is utilized to estimate the remaining time until the onset of an impending OSA episode. The approach was tested using three datasets including (1 20 records from 14 OSA subjects in benchmark ECG apnea databases (Physionet.org, (2 records of 10 OSA patients from the University of Dublin OSA database and (3 records of eight subjects from previous work. Validation tests suggest that the model can be used to track the time until the onset of an OSA episode with the likelihood of correctly predicting apnea onset in 1 min to 5 mins ahead is 83.6 ± 9.3%, 80 ± 8.1%, 76.2 ± 13.3%, 66.9 ± 15.4%, and 61.1 ± 16.7%, respectively. The present prognosis approach can be integrated with wearable devices, enhancing proactive treatment of OSA and real-time wearable sensor-based of sleep disorders.

Self-reported sleep bruxism and nocturnal gastroesophageal reflux disease in patients with obstructive sleep apnea: relationship to gender and ethnicity.

Science.gov (United States)

Hesselbacher, Sean; Subramanian, Shyam; Rao, Shweta; Casturi, Lata; Surani, Salim

2014-01-01

Nocturnal bruxism is associated with gastroesophageal reflux disease (GERD), and GERD is strongly associated with obstructive sleep apnea (OSA). Gender and ethnic differences in the prevalence and clinical presentation of these often overlapping sleep disorders have not been well documented. Our aim was to examine the associations between, and the symptoms associated with, nocturnal GERD and sleep bruxism in patients with OSA, and to examine the influence of gender and ethnicity. A retrospective chart review was performed of patients diagnosed with OSA at an academic sleep center. The patients completed a sleep questionnaire prior to undergoing polysomnography. Patients with confirmed OSA were evaluated based on gender and ethnicity. Associations were determined between sleep bruxism and nocturnal GERD, and daytime sleepiness, insomnia, restless legs symptoms, and markers of OSA severity in each group. In these patients with OSA, the prevalence of nocturnal GERD (35%) and sleep bruxism (26%) were higher than the general population. Sleep bruxism was more common in Caucasians than in African Americans or Hispanics; there was no gender difference. Nocturnal GERD was similar among all gender and ethnic groups. Bruxism was associated with nocturnal GERD in females, restless legs symptoms in all subjects and in males, sleepiness in African Americans, and insomnia in Hispanics. Nocturnal GERD was associated with sleepiness in males and African Americans, insomnia in females, and restless legs symptoms in females and in Caucasians. Patients with OSA commonly have comorbid sleep bruxism and nocturnal GERD, which may require separate treatment. Providers should be aware of differences in clinical presentation among different ethnic and gender groups.

Mapping Global Ocean Surface Albedo from Satellite Observations: Models, Algorithms, and Datasets

Science.gov (United States)

Li, X.; Fan, X.; Yan, H.; Li, A.; Wang, M.; Qu, Y.

2018-04-01

Ocean surface albedo (OSA) is one of the important parameters in surface radiation budget (SRB). It is usually considered as a controlling factor of the heat exchange among the atmosphere and ocean. The temporal and spatial dynamics of OSA determine the energy absorption of upper level ocean water, and have influences on the oceanic currents, atmospheric circulations, and transportation of material and energy of hydrosphere. Therefore, various parameterizations and models have been developed for describing the dynamics of OSA. However, it has been demonstrated that the currently available OSA datasets cannot full fill the requirement of global climate change studies. In this study, we present a literature review on mapping global OSA from satellite observations. The models (parameterizations, the coupled ocean-atmosphere radiative transfer (COART), and the three component ocean water albedo (TCOWA)), algorithms (the estimation method based on reanalysis data, and the direct-estimation algorithm), and datasets (the cloud, albedo and radiation (CLARA) surface albedo product, dataset derived by the TCOWA model, and the global land surface satellite (GLASS) phase-2 surface broadband albedo product) of OSA have been discussed, separately.

Obstructive Sleep Apnea in MPS

Directory of Open Access Journals (Sweden)

Abhijit Ricky Pal MBBChir, MA, MD, FRCS(ORL-HNS

2015-11-01

Full Text Available The mucopolysaccharidoses (MPSs are a group of inherited, metabolic disorders characterized by progressive multisystem accumulation of partially degraded glycosaminoglycans. This manifests with multilevel airway obstruction, presenting with obstructive sleep apnea (OSA. We systematically reviewed the literature to determine the severity and prevalence of OSA in MPS based on polysomnography analysis. Fifteen studies with 294 participants met the inclusion criteria for review. The pretreatment prevalence of OSA in MPS was 81% with a mean apnea–hypopnea index (AHI of 10.4. Patients with MPS I are most significantly affected, with 75% suffering with moderate to severe OSA (mean AHI, 16.6. Enzyme replacement therapy (ERT results in an almost significant reduction in OSA in MPS I ( P = .06, while adenotonsillar surgery significantly improves AHI ( P = .002. Obstructive sleep apnea least affects MPS III. There is a lack of long-term post-ERT and hematopoietic stem cell transplant data relating to OSA outcomes in this population, with further prospective studies required to determine the ongoing response to treatment.

Regeneración natural de plantas leñosas en una plantación costarricense de Vochysia guatemalensis (Vochysiaceae y el efecto de la fertilización con P y NPK

Directory of Open Access Journals (Sweden)

José Fco Di Stefano

2009-11-01

Full Text Available Las estrategias de manejo y las especies seleccionadas en plantaciones forestales pueden tener efectos positivos o negativos sobre la regeneración vegetal en los trópicos. Esta investigación estudió la abundancia y riqueza de plantas leñosas bajo el dosel de un monocultivo de Vochysia guatemalensis de diez años. Se evaluaron 19 parcelas de 80 m²en Tabarcia de Mora, con varios tratamientos de fertilización (0-0; 0-50; 50-0, 50-50 g/ planta de P, y NPK, respectivamente, este ultimó se aumentó de 150 a 200 g hasta que la plantación alcanzó los seis años, en un diseño factorial totalmente al azar. Se contaron e identificaron todas las especies leñosas con más de 0.5 m de altura, con un total de aproximadamente 10 000 ind/ha en 90 especies, siendo éstas principalmente nativas de la zona (varias maderables, otras importantes para la fauna, la mayoría con bajos índices de importancia (suma de la densidad y frecuencias relativas. Un 16% alcanzaron alturas superiores a 2.5 m. Se considera que varios factores pudieron favorecer dicha regeneración, como un dosel con una apertura inter-media, un manejo forestal de bajo impacto, la cercanía de un fragmento boscoso maduro, y el establecimiento de la plantación en sustitución de un cafetal donde se aplicaban estrategias de conservación de suelos y se fertilizaba anualmente. Finalmente, se determinó una mayor abundancia y riqueza en las parcelas con solo P (χ²=15.364, gl=3, p=0.002, probablemente porque los árboles de Vochysia tendieron a ser menos desarrollados en comparación con los otros tratamientos.

Probing for Reasons: Presentations, Questions, Phases

Science.gov (United States)

Morris, Kellyn Farlow; Speiser, Bob

2010-01-01

This paper reports on a research study based on data from experimental teaching. Undergraduate dance majors were invited, through real-world problem tasks that raised central conceptual issues, to invent major ideas of calculus. This study focuses on work and thinking by these students, as they sought to build key ideas, representations and…

78 FR 18674 - Invitation for Public Comment on Draft DOT Research, Development and Technology Strategic Plan...

Science.gov (United States)

2013-03-27

... and strategic process to cover the years 2013-2018, and responds to feedback from the National... administrations. Two cross-modal bodies participated in the process: the RD&T Planning Team Council (composed of...-0002] Invitation for Public Comment on Draft DOT Research, Development and Technology Strategic Plan...

Impaired behavioral and neurocognitive function in preschool children with obstructive sleep apnea.

Science.gov (United States)

Landau, Yael E; Bar-Yishay, Orit; Greenberg-Dotan, Sari; Goldbart, Aviv D; Tarasiuk, Ariel; Tal, Asher

2012-02-01

We aimed to examine the hypothesis that behavioral and neurocognitive functions of preschool children with Obstructive Sleep Apnea Syndrome (OSAS) are impaired compared to healthy children, and improve after adenotonsillectomy (TA). A comprehensive assessment battery was used to assess cognitive and behavioral functions, and quality of life in children with OSAS compared to matched controls. 45 children (mean age 45.5 ± 9 months, 73% boys, BMI 15.7 ± 2) with OSAS were compared to 26 healthy children (mean age 48.6 ± 8 months, 46% boys, BMI 16.4 ± 2). Mean AHI in the OSAS group was 13.2 ± 10.7 (ranging from 1.2 to 57). Significantly impaired planning and fluency (executive function) were found in children with OSAS, as well as impaired attention and receptive vocabulary. Parents and teachers described the OSAS group as having significantly more behavior problems. Quality of life questionnaire in children with OSAS (mean 2.3, range 0.7-4.3) was significantly worse compared to controls (mean 0, range: 0-4), P improvement was documented in verbal and motor fluency, sustained attention, and vocabulary. After TA, fewer behavioral problems were seen. Preschool children with OSAS present significantly impaired executive functions, impaired attention and receptive vocabulary, and more behavior problems. One year after TA, the prominent improvements were in behavior and quality of life. These findings suggest that the impact of OSAS on behavioral and cognitive functions begins in early childhood. Copyright © 2011 Wiley Periodicals, Inc.

Leaching of PAHs from agricultural soils treated with oil shale combustion ash: an experimental study.

Science.gov (United States)

Jefimova, Jekaterina; Adamson, Jasper; Reinik, Janek; Irha, Natalya

2016-10-01

The present study focuses on the fate of polycyclic aromatic hydrocarbons (PAHs) in soils amended with oil shale ash (OSA). Leachability studies to assess the release of PAHs to the environment are essential before the application of OSA in agriculture. A quantitative estimation of the leaching of PAHs from two types of soil and two types of OSA was undertaken in this study. Two leaching approaches were chosen: (1) a traditional one step leaching scheme and (2) a leaching scheme with pretreatment, i.e.., incubation of the material in wet conditions imitating the field conditions, followed by a traditional leaching procedure keeping the total amount of water constant. The total amount of PAHs leached from soil/OSA mixtures was in the range of 15 to 48 μg/kg. The amount of total PAHs leached was higher for the incubation method, compared to the traditional leaching method, particularly for Podzolic Gleysols soil. This suggests that for the incubation method, the content of organic matter and clay minerals of the soil influence the fate of PAHs more strongly compared to the traditional leaching scheme. The amount of PAHs leached from OSA samples is higher than from soil/OSA mixtures, which suggests soils to inhibit the release of PAHs. Calculated amount of PAHs from experimental soil and OSA leaching experiments differed considerably from real values. Thus, it is not possible to estimate the amount of PAHs leached from soil/OSA mixtures based on the knowledge of the amount of PAHs leached from soil and OSA samples separately.

The effect of the severity of obstructive sleep apnea syndrome on telomere length.

Science.gov (United States)

Tempaku, Priscila Farias; Mazzotti, Diego Robles; Hirotsu, Camila; Andersen, Monica Levy; Xavier, Gabriela; Maurya, Pawan Kumar; Rizzo, Lucas Bortolotto; Brietzke, Elisa; Belangero, Sintia Iole; Bittencourt, Lia; Tufik, Sergio

2016-10-25

Aging is associated with an increase in the prevalence of obstructive sleep apnea syndrome (OSAS) as well as the shortening of telomeres. It is known that OSAS-related factors are stimuli that can contribute to the acceleration of cellular senescence. Thus, the present study aimed to compare the leukocyte telomere length (LTL) between OSAS patients and controls, as well as to verify the correlation between LTL and sleep parameters. We used DNA extracted of 928 individuals from EPISONO to measure the LTL by the quantitative real-time polymerase chain reaction. All individuals were subjected to one full-night polysomnography. LTL was significantly shorter in OSAS patients compared to controls. The results showed negative correlations between LTL and the following variables: apnea-hypopnea index, respiratory disturbance index, desaturation index and wake after sleep onset. LTL was positively correlated with sleep efficiency, total sleep time, basal, minimum and maximum oxygen saturation. Lastly, it was observed that OSAS severity was associated with shorter LTL even after adjusting for sex, age, years of schooling, body mass index, diabetes, stroke and heart attack. In conclusion, our study indicates the presence of an association between LTL and OSAS and a significant impact of severity of OSAS in telomeres shortening.

Risk of developing obstructive sleep apnea among women with polycystic ovarian syndrome: a nationwide longitudinal follow-up study.

Science.gov (United States)

Lin, Ting-Yang; Lin, Pei-Yin; Su, Tung-Ping; Li, Cheng-Ta; Lin, Wei-Chen; Chang, Wen-Hang; Chen, Tzeng-Ji; Bai, Ya-Mei; Chen, Mu-Hong

2017-08-01

Previous cross-sectional studies have suggested a comorbid relationship between polycystic ovarian syndrome (PCOS) and obstructive sleep apnea (OSA). However, the temporal association between these two distinct diseases has not yet been investigated. Using the Taiwan National Health Insurance Research Database, 4595 women with PCOS and 4595 (1:1) age-/sex-matched controls were enrolled into the present study between 1998 and 2009, and followed to the end of 2011. Those who developed OSA during the follow-up were identified. Women with PCOS had a greater incidence of developing OSA (1.71 vs 0.63 1000 person-years, p < 0.001) than those without PCOS. The Cox regression analysis after adjusting for demographic data and medical comorbidities showed that women with PCOS had an elevated likelihood of subsequent OSA (hazard ratio: 2.63, 95% CI 1.57-4.04) during the follow-up compared to the controls. Women with PCOS were associated with an increased risk of developing OSA in later life. Further studies would be required to investigate the underlying pathophysiology between PCOS and OSA, and to clarify whether prompt intervention for PCOS would reduce the risk of OSA. Copyright © 2017 Elsevier B.V. All rights reserved.

Reduced Systemic Levels of IL-10 Are Associated with the Severity of Obstructive Sleep Apnea and Insulin Resistance in Morbidly Obese Humans

Directory of Open Access Journals (Sweden)

Sonia Leon-Cabrera

2015-01-01

Full Text Available Obstructive sleep apnea (OSA has been related to elevation of inflammatory cytokines and development of insulin resistance in morbidly obese (MO subjects. However, it is still unclear whether the systemic concentration of anti-inflammatory mediators is also affected in MO subjects directly related to the severity of OSA and level of insulin resistance. Normal weight and MO subjects were subjected to overnight polysomnography in order to establish the severity of OSA, according to the apnea-hypopnea index (AHI. Blood samples were obtained for estimation of total cholesterol and triglycerides, insulin, glucose, insulin resistance, tumor necrosis factor alpha (TNF-α, interleukin 12 (IL12, and interleukin 10 (IL-10. Serum levels of IL-10 were significantly lower in MO subjects with OSA than in MO and control individuals without OSA. Besides being inversely associated with serum TNF-α and IL-12, decreased IL-10 levels were significantly related to increased AHI, hyperinsulinemia, and insulin resistance. Serum IL-10 is significantly reduced in morbidly obese subjects with severe OSA while also showing a clear relationship with a state of hyperinsulinemia and insulin resistance probably regardless of obesity in the present sample. It may be of potential clinical interest to identify the stimulatory mechanisms of IL-10 in obese individuals with OSA.

Obstructive sleep apnea in children with cerebral palsy and epilepsy.

Science.gov (United States)

Garcia, John; Wical, Beverly; Wical, William; Schaffer, Leah; Wical, Thomas; Wendorf, Heather; Roiko, Samuel

2016-10-01

To examine the risk of obstructive sleep apnea (OSA) in children with cerebral palsy (CP) and/or epilepsy. This cross-sectional study employs the Pediatric Sleep Questionnaire (PSQ), the Gross Motor Function Classification System (GMFCS), and chart review to identify symptoms of OSA in children presenting to a multi-specialty pediatric healthcare institution. Two-hundred and fifteen patients were grouped into those with epilepsy (n=54), CP (n=18), both (n=55), and neither (comparison group, n=88). The comparison group comprised children with developmental disabilities but not children with typical development. Significantly increased PSQ scores (indicating increased risk of OSA) were found among children with CP (58%) and CP with epilepsy (67%) than among the comparison group (27%; pChildren with both CP and epilepsy had a greater number of increased PSQ scores compared with CP alone (pchildren at risk of OSA (46%) than did the medical record review for symptoms of OSA (8.2%, pChildren with CP of greater severity or comorbid epilepsy are at increased risk of OSA. This study supports the routine questionnaire-based assessment for OSA as a regular part of the care of all children with CP, especially in those with more severe CP and those with epilepsy. © 2016 Mac Keith Press.

Current trends in research and clinical issues in the study of personality and its disorders: a survey of the presentations at the ISSPD anniversary congress.

Science.gov (United States)

Simonsen, Erik; Sørensen, Per; Pedersen, Liselotte

2014-10-01

The International Society for the Study of Personality Disorders (ISSPD) celebrated its 25th anniversary in September 2013 in Copenhagen and commemorated the First International Congress at the same site. The overall theme of the congress was "Bridging Personality and Psychopathology: The Person Behind the Illness." More than 400 abstracts were submitted, and the program included 8 keynote presentations, 18 invited symposia, a debate on current controversial issues in the classification of personality disorders (Fossati, Tyrer, Livesley, and Krueger), an ISSPD award lecture (Silk), a jubilee lecture (Simonsen), a young researchers' symposium (Hopwood, Sharp, and Kaess), and special lectures on the Danish philosopher Soeren Kierkegaard and the poet Hans Christian Andersen. In this article we will survey the presentations and highlight the important issues in order to underline the current trends in research and clinical interests in personality disorders. The keynote video presentations, invited symposia, and slide presentations are freely available at www.isspd2013.com.

Análisis de la calidad de varios cuerpos de agua superficiales en el GAM y la Península de Osa utilizando el Índice Holandés Quality analysis of various surface water bodies in the GAM and the osa peninsula using the Dutch Index

Directory of Open Access Journals (Sweden)

Guillermo Calvo Brenes

2012-11-01

Full Text Available A pesar de la cantidad de ríos que tiene Costa Rica, la mayoría muestra algún grado de contaminación. Por lo tanto, resultan de particular interés aquellos que forman parte de la Gran Área Metropolitana, en donde se concentra el 70% de la población del país. Si bien la calidad del agua se puede determinar por medio del análisis de distintos indicadores, es ventajosa su simplificación por medio del uso de índices de calidad del agua. Uno de los índices adoptados en Costa Rica es el “Índice holandés de valoración de la calidad del agua” (ICA holandés, el cual se basa en el uso de tres indicadores: la demanda bioquímica de oxígeno, el nitrógeno amoniacal y el oxígeno disuelto, este último expresado como porcentaje de saturación de oxígeno. En el presente estudio se analizaron estos indicadores en diez ríos localizados en las provincias de San José, Alajuela, Heredia y Cartago, así como en la Península de Osa. Además, para correlacionar el ICA holandés con la densidad poblacional, se muestrearon tres puntos en cada río: la zona alta cercana a la naciente del río, la zona media y la zona baja, ubicada cerca de la desembocadura del río. Se encontró que los ríos que atraviesan las ciudades altamente densas, las cuales poseen densidades poblacionales superiores a los 8000 habitantes por kilómetro cuadrado (hab/km2, muestran niveles de contaminación en los ríos de “severa” a “muy severa”; por otra parte, lugares con densidades poblacionales entre los 3000-8000 hab/km2, en general, muestran niveles de contaminación de “moderada” a “severa”; mientras que los poblados con menos de 1000 hab/ km2 causan que la calidad de las aguas presente un nivel de contaminación de “incipiente” a “no contaminada”. Estos resultados pueden variar dependiendo del caudal de los ríos, su recorrido total y el uso que se le dé a la tierra. El análisis de Regresión Lineal Univariable mostró una correlaci

78 FR 35093 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel EYE DOC; Invitation for...

Science.gov (United States)

2013-06-11

... Administrative Waiver of the Coastwise Trade Laws: Vessel EYE DOC; Invitation for Public Comments AGENCY... DOC is: INTENDED COMMERCIAL USE OF VESSEL: ``Charter fishing on Lake Erie'' GEOGRAPHIC REGION: ``Ohio..., Maritime Administration. [FR Doc. 2013-13836 Filed 6-10-13; 8:45 am] BILLING CODE 4910-81-P ...

78 FR 53004 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SECOND WIND; Invitation for...

Science.gov (United States)

2013-08-27

... Administrative Waiver of the Coastwise Trade Laws: Vessel SECOND WIND; Invitation for Public Comments AGENCY... SECOND WIND is: Intended Commercial Use of Vessel: ``Breakfast, lunch, and dinner cruises featuring... to the docket number of this notice and the vessel name in order for MARAD to properly consider the...

78 FR 70097 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BEE; Invitation for Public...

Science.gov (United States)

2013-11-22

... Administrative Waiver of the Coastwise Trade Laws: Vessel BEE; Invitation for Public Comments AGENCY: Maritime... entered into this docket is available on the World Wide Web at http://www.regulations.gov . FOR FURTHER....gov . SUPPLEMENTARY INFORMATION: As described by the applicant the intended service of the vessel BEE...

78 FR 40265 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel HMS-DISCOVERY; Invitation for...

Science.gov (United States)

2013-07-03

... Administrative Waiver of the Coastwise Trade Laws: Vessel HMS-DISCOVERY; Invitation for Public Comments AGENCY... of the vessel HMS-DISCOVERY is: Intended Commercial Use of Vessel: ``Sight Seeing Tours''. Geographic... regulations at 46 CFR Part 388. Privacy Act Anyone is able to search the electronic form of all comments...

The Report of the National Invitational Conference on Consumer Protection in Postsecondary Education. Report No. 53.

Science.gov (United States)

Education Commission of the States, Denver, CO.

This report covers the background, major issues, major recommendations, and agencies and associations represented at the National Invitational Conference on Consumer Protection in Postsecondary Education held at Denver, Colorado in June 1974. Major recommendations of the conference suggest that: (1) The states should provide by legislation or by…

78 FR 19068 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel GOLDEN BOY II; Invitation for...

Science.gov (United States)

2013-03-28

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0036] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel GOLDEN BOY II; Invitation for Public Comments AGENCY... GOLDEN BOY II is: Intended Commercial Use Of Vessel: Limited charter of passengers for luxury day...

78 FR 19362 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel W.L. STEWART III; Invitation...

Science.gov (United States)

2013-03-29

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0026] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel W.L. STEWART III; Invitation for Public Comments AGENCY.... STEWART III is: Intended Commercial Use of Vessel: ``Yacht Club Regatta and Sailing Instruction Support...

SOS score: an optimized score to screen acute stroke patients for obstructive sleep apnea.

Science.gov (United States)

Camilo, Millene R; Sander, Heidi H; Eckeli, Alan L; Fernandes, Regina M F; Dos Santos-Pontelli, Taiza E G; Leite, Joao P; Pontes-Neto, Octavio M

2014-09-01

Obstructive sleep apnea (OSA) is frequent in acute stroke patients, and has been associated with higher mortality and worse prognosis. Polysomnography (PSG) is the gold standard diagnostic method for OSA, but it is impracticable as a routine for all acute stroke patients. We evaluated the accuracy of two OSA screening tools, the Berlin Questionnaire (BQ), and the Epworth Sleepiness Scale (ESS) when administered to relatives of acute stroke patients; we also compared these tools against a combined screening score (SOS score). Ischemic stroke patients were submitted to a full PSG at the first night after onset of symptoms. OSA severity was measured by apnea-hypopnea index (AHI). BQ and ESS were administered to relatives of stroke patients before the PSG and compared to SOS score for accuracy and C-statistics. We prospectively studied 39 patients. OSA (AHI ≥10/h) was present in 76.9%. The SOS score [area under the curve (AUC): 0.812; P = 0.005] and ESS (AUC: 0.789; P = 0.009) had good predictive value for OSA. The SOS score was the only tool with significant predictive value (AUC: 0.686; P = 0.048) for severe OSA (AHI ≥30/h), when compared to ESS (P = 0.119) and BQ (P = 0.191). The threshold of SOS ≤10 showed high sensitivity (90%) and negative predictive value (96.2%) for OSA; SOS ≥20 showed high specificity (100%) and positive predictive value (92.5%) for severe OSA. The SOS score administered to relatives of stroke patients is a useful tool to screen for OSA and may decrease the need for PSG in acute stroke setting. Copyright © 2014 Elsevier B.V. All rights reserved.

Back to the Future? Presenting archaeology at the Green Man Festival

Directory of Open Access Journals (Sweden)

Matt Law

2017-01-01

Full Text Available In the summer of 2011, Cardiff Osteoarchaeology Research Group was invited to present a number of archaeological engagement activities at the Green Man music festival as part of the Einstein’s Garden science learning area. The project, called Back to the Future?: Animals and archaeology in Einstein’s Garden comprised a number of activities, designed to cater for a wide range of ages as the festival audience typically includes young people and families. Over four days more than 2000 people visited the stall. This paper will briefly outline the activities presented, and will reflect on the challenges posed by outreach at a music festival, in particular how to hook the main festival demographic, and how to evaluate success.

The Kaleidoscope of Culture: expanding the museum experience and the museum narrative by inviting visitors into the curatorial process

Directory of Open Access Journals (Sweden)

Kirsten Jensen

2015-07-01

Full Text Available Traditional art museum exhibitions are planned according to art-historical elements. At Trapholt – a museum of modern Danish art, design and applied art in Denmark, we are interested in exploring what happens when ordinary visitors are invited to curate personal exhibitions in the museum space. This paper analyses the project The Kaleidoscope of Culture, where people with no art historical background were invited to curate exhibitions based on the Trapholt collection of art and their own cultural backgrounds and experiences. The main argument is that, by allowing these personal voices in the museum space, new museum narratives are established. But to make the museum a truly transformative space the art- historical knowledge and methods must also be activate.

78 FR 14413 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel LUCKY DUCK; Invitation for...

Science.gov (United States)

2013-03-05

... Administrative Waiver of the Coastwise Trade Laws: Vessel LUCKY DUCK; Invitation for Public Comments AGENCY... should refer to docket number MARAD-2013-0019. Written comments may be submitted by hand or by mail to... LUCKY DUCK is: Intended Commercial Use Of Vessel: ``The vessel is to be operated as a sailing...

Massive Scrotal Edema: An Unusual Manifestation of Obstructive Sleep Apnea and Obesity-Hypoventilation Syndrome

Directory of Open Access Journals (Sweden)

Stephanie E. Dreifuss

2013-01-01

Full Text Available Obstructive sleep apnea (OSA may occur in association with obesity-hypoventilation (Pickwickian syndrome, a disorder of ventilatory control affecting individuals with morbid obesity. Through the pressor effects of chronic hypercapnia and hypoxemia, this syndrome may result in pulmonary hypertension, right heart failure, and massive peripheral edema. We present a case of severe scrotal edema in a 36-year-old male with OSA and obesity-hypoventilation syndrome. A tracheostomy was performed to relieve hypoxemia and led to dramatic improvement of scrotal edema. No scrotal surgery was necessary. Followup at two months showed complete resolution of scrotal edema, improvement in mental status, and normalization of arterial blood gas measurements. This case demonstrates that OSA and obesity-hypoventilation syndrome may present with massive scrotal edema. Furthermore, if OSA is recognized as the cause of right heart failure, and if the apnea is corrected, the resultant improvement in cardiac function may allow reversal of massive peripheral, including scrotal, edema.

Massive scrotal edema: an unusual manifestation of obstructive sleep apnea and obesity-hypoventilation syndrome.

Science.gov (United States)

Dreifuss, Stephanie E; Manders, Ernest K

2013-01-01

Obstructive sleep apnea (OSA) may occur in association with obesity-hypoventilation (Pickwickian) syndrome, a disorder of ventilatory control affecting individuals with morbid obesity. Through the pressor effects of chronic hypercapnia and hypoxemia, this syndrome may result in pulmonary hypertension, right heart failure, and massive peripheral edema. We present a case of severe scrotal edema in a 36-year-old male with OSA and obesity-hypoventilation syndrome. A tracheostomy was performed to relieve hypoxemia and led to dramatic improvement of scrotal edema. No scrotal surgery was necessary. Followup at two months showed complete resolution of scrotal edema, improvement in mental status, and normalization of arterial blood gas measurements. This case demonstrates that OSA and obesity-hypoventilation syndrome may present with massive scrotal edema. Furthermore, if OSA is recognized as the cause of right heart failure, and if the apnea is corrected, the resultant improvement in cardiac function may allow reversal of massive peripheral, including scrotal, edema.

Cost-effectiveness of invitation to food supplementation early in pregnancy combined with multiple micronutrients on infant survival: analysis of data from MINIMat randomized trial, Bangladesh.

Science.gov (United States)

Shaheen, Rubina; Persson, Lars Åke; Ahmed, Shakil; Streatfield, Peter Kim; Lindholm, Lars

2015-05-28

Absence of cost-effectiveness (CE) analyses limits the relevance of large-scale nutrition interventions in low-income countries. We analyzed if the effect of invitation to food supplementation early in pregnancy combined with multiple micronutrient supplements (MMS) on infant survival represented value for money compared to invitation to food supplementation at usual time in pregnancy combined with iron-folic acid. Outcome data, infant mortality (IM) rates, came from MINIMat trial (Maternal and Infant Nutrition Interventions, Matlab, ISRCTN16581394). In MINIMat, women were randomized to early (E around 9 weeks of pregnancy) or usual invitation (U around 20 weeks) to food supplementation and daily doses of 30 mg, or 60 mg iron with 400 μgm of folic acid, or MMS with 15 micronutrients including 30 mg iron and 400 μgm of folic acid. In MINIMat, EMMS significantly reduced IM compared to UFe60F (U plus 60 mg iron 400 μgm Folic acid). We present incremental CE ratios for incrementing UFe60F to EMMS. Costing data came mainly from a published study. By incrementing UFe60F to EMMS, one extra IM could be averted at a cost of US$907 and US$797 for NGO run and government run CNCs, respectively, and at US$1024 for a hypothetical scenario of highest cost. These comparisons generated one extra life year (LY) saved at US$30, US$27, and US$34, respectively. Incrementing UFe60F to EMMS in pregnancy seems worthwhile from health economic and public health standpoints. Maternal and Infant Nutrition Interventions, Matlab; ISRCTN16581394 ; Date of registration: Feb 16, 2009.

Self-Reported Sleep Bruxism and Nocturnal Gastroesophageal Reflux Disease in Patients with Obstructive Sleep Apnea: Relationship to Gender and Ethnicity§

Science.gov (United States)

Hesselbacher, Sean; Subramanian, Shyam; Rao, Shweta; Casturi, Lata; Surani, Salim

2014-01-01

Study Objectives : Nocturnal bruxism is associated with gastroesophageal reflux disease (GERD), and GERD is strongly associated with obstructive sleep apnea (OSA). Gender and ethnic differences in the prevalence and clinical presentation of these often overlapping sleep disorders have not been well documented. Our aim was to examine the associations between, and the symptoms associated with, nocturnal GERD and sleep bruxism in patients with OSA, and to examine the influence of gender and ethnicity. Methods : A retrospective chart review was performed of patients diagnosed with OSA at an academic sleep center. The patients completed a sleep questionnaire prior to undergoing polysomnography. Patients with confirmed OSA were evaluated based on gender and ethnicity. Associations were determined between sleep bruxism and nocturnal GERD, and daytime sleepiness, insomnia, restless legs symptoms, and markers of OSA severity in each group. Results : In these patients with OSA, the prevalence of nocturnal GERD (35%) and sleep bruxism (26%) were higher than the general population. Sleep bruxism was more common in Caucasians than in African Americans or Hispanics; there was no gender difference. Nocturnal GERD was similar among all gender and ethnic groups. Bruxism was associated with nocturnal GERD in females, restless legs symptoms in all subjects and in males, sleepiness in African Americans, and insomnia in Hispanics. Nocturnal GERD was associated with sleepiness in males and African Americans, insomnia in females, and restless legs symptoms in females and in Caucasians. Conclusion : Patients with OSA commonly have comorbid sleep bruxism and nocturnal GERD, which may require separate treatment. Providers should be aware of differences in clinical presentation among different ethnic and gender groups. PMID:25352924

PREFACE: 1st International School and Conference "Saint Petersburg OPEN 2014" on Optoelectronics, Photonics, Engineering and Nanostructures

Science.gov (United States)

2014-09-01

Dear Colleagues, 1st International School and Conference "Saint Petersburg OPEN 2014" on Optoelectronics, Photonics, Engineering and Nanostructures was held on March 25 - 27, 2014 at St. Petersburg Academic University - Nanotechnology Research and Education Centre of the Russian Academy of Sciences. The School and Conference included a series of invited talks given by leading professors with the aim to introduce young scientists with actual problems and major advances in physics and technology. The keynote speakers were: Mikhail Glazov (Ioffe Physico-Technical Institute RAS, Russia) Vladimir Dubrovskii (Saint Petersburg Academic University RAS, Russia) Alexey Kavokin (University of Southampton, United Kingdom and St. Petersburg State University, Russia) Vladimir Korenev (Ioffe Physico-Technical Institute RAS, Russia) Sergey Kukushkin (Institute of Problems of Mechanical Engineering RAS, Russia) Nikita Pikhtin (Ioffe Physico-Technical Institute RAS, Russia and "Elfolum" Ltd., Russia) Dmitry Firsov (Saint Petersburg State Polytechnical University, Russia) During the poster session all undergraduate and graduate students attending the conference presented their works. Sufficiently large number of participants with more than 160 student attendees from all over the world allowed the Conference to provide a fertile ground for the fruitful discussions between the young scientists as well as to become a perfect platform for the valuable discussions between student authors and highly experienced scientists. The best student papers, which were selected by the Program Committee and by the invited speakers basing on the theses and their poster presentation, were awarded with diplomas of the conference - see the photos. This year's School and Conference is supported by SPIE (The International Society for Optics and Photonics), OSA (The Optical Society), St. Petersburg State Polytechnical University and by Skolkovo Foundation. It is a continuation of the annual schools and

PREFACE: 2nd International School and Conference Saint-Petersburg OPEN on Optoelectronics, Photonics, Engineering and Nanostructures (SPbOPEN2015)

Science.gov (United States)

2015-11-01

The 2nd International School and Conference ''Saint Petersburg OPEN 2015'' on Optoelectronics, Photonics, Engineering and Nanostructures was held on April 6 - 8, 2015 at St. Petersburg Academic University. The School and Conference included a series of invited talks given by leading professors with the aim to introduce young scientists with actual problems and major advances in physics and technology. The keynote speakers were Mikhail V. Maximov (Ioffe Physico-Technical Institute RAS, Russia) Vladimir G. Dubrovskii (St. Petersburg Academic University and St. Petersburg State University, Russia) Anton Yu. Egorov (JSC Connector Optics, Russia) Victor V. Luchinin (St. Petersburg State Electrotechnical University, Russia) Vladislav E. Bugrov (St. Petersburg University of Internet Technologies, Mechanics and Optics, Russia) Vitali A. Schukin (VI Systems, Germany) Yuri P. Svirko (University of Eastern Finland, Finland) During the poster session all undergraduate and graduate students attending the conference presented their works. A sufficiently large number of participants, with more than 170 student attendees from all over the world, allowed the Conference to provide a fertile ground for fruitful discussions between the young scientists as well as to become a perfect platform for valuable discussions between student authors and highly experienced scientists. The best student papers, which were selected by the Program Committee and by the invited speakers basing on the theses and their poster presentation, were awarded with diplomas of the conference - see the photos. This year ''Saint Petersburg OPEN 2015'' is organized by St. Petersburg Academic University in cooperation with Peter the Great St. Petersburg Polytechnic University. The School and Conference is supported by Russian Science Foundation, SPIE (The International Society for Optics and Photonics), OSA (The Optical Society) and by Skolkovo Foundation. It is a continuation of the annual schools and seminars for

Prevalence of obstructive sleep apnea in Asian adults: a systematic review of the literature

Directory of Open Access Journals (Sweden)

Mirrakhimov Aibek E

2013-02-01

Full Text Available Abstract Background Obstructive sleep apnea (OSA is a common disease, affecting approximately 2% of women and 4% of men residing in Western communities. No systematically reviewed data are available about the prevalence of this disease in Asia, the most heavily populated continent. Methods PubMed/Medline, Scopus and Google Scholar were searched for articles published from 1993 to May 2012 that reported the prevalence of OSA diagnosed via sleep monitoring and the prevalence of patients at risk for OSA as assessed by symptomatology and/or sleep questionnaires. We have also searched abstract database of major pulmonary and sleep scientific societies for relevant abstracts presented from 2010 to 2012. The following inclusion criteria were used: articles published in English, age ≥ 18 years, ≥ 100 participants in studies using sleep monitoring for the diagnosis of OSA, ≥ 300 participants in studies using questionnaires to detect patients at high risk for OSA. Exclusion criteria: duplicate publications, studies reporting the prevalence of central sleep apnea only, hospital based studies as well as studies assessing OSA prevalence among patients with resistant arterial hypertension, chronic kidney disease, heart failure and in patients with concomitant neurological disease. Results Twenty four articles were found to meet the inclusion criteria, covering 47,957 subjects (26,042 men and 21,915 women and four relevant abstracts were noted. OSA prevalence ranged from 3.7% to 97.3%. Male gender, older age, a higher BMI and waist to hip ratio, greater neck circumference, arterial hypertension, smoking, snoring and daytime sleepiness were associated with OSA. Sample size, difference between the populations studied and the fact that some works included patients with a high pre-test probability of OSA explain the difference in prevalence rates. Conclusion This systematic review highlights the lack of data regarding the prevalence of OSA in Asians

Metabolic biomarkers in community obese children: effect of obstructive sleep apnea and its treatment.

Science.gov (United States)

Alonso-Álvarez, María Luz; Terán-Santos, Joaquin; Gonzalez Martinez, Mónica; Cordero-Guevara, José Aurelio; Jurado-Luque, María José; Corral-Peñafiel, Jaime; Duran-Cantolla, Joaquin; Ordax Carbajo, Estrella; MasaJimenez, Fernando; Kheirandish-Gozal, Leila; Gozal, David

2017-09-01

Obesity and obstructive sleep apnea in children have been associated with metabolic morbidities. The present study aimed to evaluate the presence of metabolic alterations among obese children recruited from the community, with and without obstructive sleep apnea syndrome (OSAS), and the impact of treatment of OSAS on metabolic profiles. A cross-sectional, prospective, multicenter study of Spanish children aged 3-14 years with a body mass index (BMI) ≥95th percentile for age and sex were randomly selected in the first phase. Four groups emerged for follow-up: (1) no treatment; (2) dietary intervention; (3) surgical treatment of OSA; and (4) continuous positive airway pressure (CPAP) treatment of OSA. Fasting blood tests were performed at baseline (T0) and approximately one year after the intervention (T1). A total of 113 obese children with a mean age of 11.3 ± 2.9 years completed T0 and T1 assessments. Their mean BMI z-score at T1 was 1.34 ± 0.59, and mean Respiratory Disturbance Index was 8.6 ± 13.0 at T0 and 3.3 ± 4.0/hour total sleep time at T1. Only glucose fasting levels differed among metabolic parameters in obese children with OSAS and without OSAS at baseline (T0) (p = 0.018). There were statistically significant differences between surgically treated OSAS (p = 0.002), and CPAP-treated OSAS (p = 0.024) versus the non-OSAS group in the glucose levels between baseline (T0) and follow-up (T1) after controlling for age and change in BMI. Significant univariate associations between BMI and C-reactive protein, insulin, and homeostasis model assessment of insulin resistance emerged at both T0 and T1. Concurrent obesity and OSAS could promote metabolic and inflammatory alterations, and the latter appeared to be sensitive to OSAS treatment outcomes. ClinicalTrials.gov Identifier: NCT01322763. Copyright © 2017 Elsevier B.V. All rights reserved.

APT related papers presented at the 1997 particle accelerator conference, Vancouver, May 12--16, 1997

International Nuclear Information System (INIS)

Lawrence, G.

1997-07-01

Tritium is essential for the US nuclear weapons to function, but because it is radioactive with a half-life of 12.3 years, the supply must be periodically replenished. Presently, only reactor or accelerator systems can be used to produce tritium. This report is a compilation of 31 papers given at the 1997 Particle Accelerator Conference which dealt with the accelerator production of tritium. The papers are grouped into two categories, invited and contributed

APT related papers presented at the 1997 particle accelerator conference, Vancouver, May 12--16, 1997

Energy Technology Data Exchange (ETDEWEB)

Lawrence, G. [comp.

1997-07-01

Tritium is essential for the US nuclear weapons to function, but because it is radioactive with a half-life of 12.3 years, the supply must be periodically replenished. Presently, only reactor or accelerator systems can be used to produce tritium. This report is a compilation of 31 papers given at the 1997 Particle Accelerator Conference which dealt with the accelerator production of tritium. The papers are grouped into two categories, invited and contributed.

Cognitive and behavioral effects of obstructive sleep apnea syndrome in children: a systematic literature review.

Science.gov (United States)

da Silva Gusmão Cardoso, Thiago; Pompéia, Sabine; Miranda, Mônica Carolina

2018-06-01

Obstructive sleep apnea syndrome (OSA) is a common respiratory sleep disorder in children that is believed to adversely affect both quality of life and cognition. The purpose of the present systematic review was to obtain evidence of the impact of OSA on children's cognitive/behavioral abilities from primary studies published in MEDLINE/PubMed, LILACS, SciELO, ISI Web of Science, and PsycINFO databases from 2002 to 2016. Of the 649 articles found, only 34 met the eligibility criteria: studies that evaluated cognition, behavior, and/or academic achievement of children meeting clinical criteria for OSA to compare their data to those of healthy controls or normative data, provided that the samples did not present conditions that might affect cognition/behavior irrespective of OSA. The few selected articles with low risk of bias (levels of evidence I and II) showed that OSA children's intellectual abilities may be impaired but remain within the normal range. Which specific cognitive ability drives this impairment is unclear, as there was insufficient evidence of deficits in language, memory, attention, executive functions, and academic performance, due to low levels of evidence, conflicting findings, and/or heterogeneity of tasks and cognitive abilities tapped by the measures used to assess these domains. To determine why this is so, future studies must test OSA patients using measures that allow for fractionated higher- and lower-order cognitive abilities based on accepted cognitive neuropsychology models. Copyright © 2018 Elsevier B.V. All rights reserved.

The Management of Co-Morbidities in Patients with Heart Failure – Obstructive Sleep Apnoea

Directory of Open Access Journals (Sweden)

Andrew J Stewart Coats

2017-01-01

Full Text Available Heart failure (HF patients are older and frequently present with multiple co-morbidities. Co- morbidities worsen patient symptoms and may contribute to the progression of heart failure, increase mortality or limit the therapeutic response to treatment. Obstructive sleep apnoea (OSA affects 2–4% of the adult population world-wide and is associated with similar risk factors to HF, meaning it is a frequent finding in HF patients, including HFrEF, HFmrEF and HFpEF. OSA has consistently been shown to be associated with hypertension, coronary artery disease, arrhythmias, heart failure, and stroke. A thorough understanding of the diagnosis and treatment options of OSA is of paramount importance to the practising HF clinician. Patients may present to the HF specialist having been diagnosed by a formal sleep study or may be suspected of OSA because of symptoms of snoring, reports of obstructed breathing by the sleep partner or day-time sleepiness. The mainstay of treatment for OSA is a positive airway pressure mask which can be used in mild moderate and severe OSA. The need for therapy should be discussed with the patient and if the AHI is above 15/ hr then treatment is indicated to reduce this to below 15. This is a consensus recommendation and no adequately powered clinical trials have shown this improves either mortality or the risk of disease progression. Other options are discussed

Implantação e impacto do Programa Nacional de Suplementação de Ferro no município de Viçosa - MG Implementation and impact of the National Iron Supplementation Program in the city of Viçosa, State of Minas Gerais

Directory of Open Access Journals (Sweden)

Catarina Machado Azeredo

2011-10-01

Full Text Available Objetivou-se avaliar a implantação do Programa Nacional de Suplementação de Ferro no município de Viçosa/MG e seu impacto em lactentes não anêmicos de 6 a 18 meses de idade, atendidos pelas Equipes de Saúde da Família. Realizou-se entrevistas aos profissionais de nível superior e às mães/responsáveis pelas crianças. As crianças não anêmicas e que não recebiam suplementação anteriormente (n=133 foram suplementadas com xarope de sulfato ferroso por seis meses. Realizou-se dosagem de hemoglobina, avaliação antropométrica e de condições socioeconômicas, antes e após os seis meses. Classificou-se como alta adesão as crianças que ingeriram 75% ou mais da dose prescrita e como baixa adesão as demais, de acordo com o referido pelas mães. Sobre a implantação do PNSF no município, observou-se que o sistema de distribuição nem sempre foi acessível ao grupo prioritário e houve ausência de capacitação e motivação da maioria dos Agentes Comunitários de Saúde; sobre o grupo prioritário observou-se ausência de divulgação para promoção do PNSF, além de sensibilização e educação somente de parte das mães; quanto ao suplemento as crianças tiveram baixa adesão e a dosagem não foi efetiva na prevenção da anemia. Portanto, a implantação do PNSF no município revelou entraves operacionais importantes.The scope of this work was to evaluate the implementation of the National Iron Supplementation Program (NISP in Viçosa in the State of Minas Gerais and its impact on 6- to 18-month-old non-anemic infants assisted by the Family Health Teams. Interviews were conducted with the professionals and with the children's mothers/guardians. The non-anemic children who didn't receive the earlier supplementation (n=133 were given ferrous sulphate syrup for six months. Hemoglobin dosage, anthropometric evaluation and a socioeconomic survey were conducted before and after the six-month period. Children who ingested 75

Time to finger point or fix? An invitation to join ongoing efforts to promote ethical authorship and other good publication practices.

Science.gov (United States)

Woolley, Karen L; Gertel, Art; Hamilton, Cindy W; Jacobs, Adam; Snyder, Gene P

2013-01-01

In this commentary, we present evidence that unethical authorship (eg, guest and ghost authoring) and other publication practices are not restricted to the pharmaceutical industry; they also occur in academia. Such practices are not an industry problem--they are a research problem. To enhance trust in industry-sponsored research, companies have made rapid and far-reaching changes to their publication guidelines, policies, and procedures. Professional medical writers have adopted, and continue to implement, these changes. Although evidence indicates that industry practices are improving, there is certainly more to do, both in industry and academia. We invite readers to join ongoing efforts to promote ethical publication practices.

The consolidation of implicit sequence memory in obstructive sleep apnea.

Directory of Open Access Journals (Sweden)

Eszter Csabi

Full Text Available Obstructive Sleep Apnea (OSA Syndrome is a relatively frequent sleep disorder characterized by disrupted sleep patterns. It is a well-established fact that sleep has beneficial effect on memory consolidation by enhancing neural plasticity. Implicit sequence learning is a prominent component of skill learning. However, the formation and consolidation of this fundamental learning mechanism remains poorly understood in OSA. In the present study we examined the consolidation of different aspects of implicit sequence learning in patients with OSA. We used the Alternating Serial Reaction Time task to measure general skill learning and sequence-specific learning. There were two sessions: a learning phase and a testing phase, separated by a 10-hour offline period with sleep. Our data showed differences in offline changes of general skill learning between the OSA and control group. The control group demonstrated offline improvement from evening to morning, while the OSA group did not. In contrast, we did not observe differences between the groups in offline changes in sequence-specific learning. Our findings suggest that disrupted sleep in OSA differently affects neural circuits involved in the consolidation of sequence learning.

Predictors of Obstructive Sleep Apnea Risk among Blacks with Metabolic Syndrome.

Science.gov (United States)

Rogers, A; Ravenell, J; Donat, M; Sexias, A; Ogedegbe, C; McFarlane, S I; Jean-Louis, G

Identification of risk factors for obstructive sleep apnea (OSA) is important to enable comprehensive intervention to reduce OSA-related cardiovascular disease (CVD). The metabolic syndrome outcome study (MetSO) provides a unique opportunity to address these factors. This study investigated risk of OSA among blacks with metabolic syndrome. The present study utilized data from MetSO, an NIH-funded cohort study of blacks with metabolic syndrome. A total of 1,035 patients provided data for the analysis. These included sociodemographic factors, health risks, and medical history. Physician-diagnosed conditions were obtained using an electronic medical record system (Allscripts, Sunrise Enterprise). Patients were diagnosed with metabolic syndrome using criteria articulated in the joint interim statement for harmonizing the metabolic syndrome. Patients with a score ≥6 on the Apnea Risk Evaluation System (ARES) questionnaire were considered at risk for OSA. Obesity is defined by body mass index (BMI ≥ 30 kg/m 2 ). Of the 1,035 patients screened in the MetSO cohort, 48.9% were at high risk for OSA. Using multivariate-adjusted logistic regression analysis, we observed that obesity was the strongest predictor of OSA risk (OR=1.59, 95%CI=1.24-2.04, pmetabolic syndrome.

75 FR 39001 - Notice Inviting Comments on Priorities To Be Proposed to the National Board for Education...

Science.gov (United States)

2010-07-07

... Higher Education Act of 1965, as amended; such as closing the achievement gap; ensuring that all children... evaluation. The Institute will facilitate the use of education statistics, research, and evaluation in... DEPARTMENT OF EDUCATION [Docket ID ED-2010-IES-0008] Notice Inviting Comments on Priorities To Be...

77 FR 49059 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel CHAT DE MER; Invitation for...

Science.gov (United States)

2012-08-15

... Administrative Waiver of the Coastwise Trade Laws: Vessel CHAT DE MER; Invitation for Public Comments AGENCY....gov . SUPPLEMENTARY INFORMATION: As described by the applicant the intended service of the vessel CHAT... Francisco Bay. Geographic Region: ``California.'' The complete application is given in DOT docket MARAD-2012...

Neutrino 2004: Collection of Presentations

International Nuclear Information System (INIS)

2004-01-01

The scientific program covers the latest developments in neutrino physics, astrophysics and related topics through a set of invited talks and 2 poster sessions. The following issues are addressed: - solar neutrinos, - atmospheric neutrinos, - short and long baseline experiments, - neutrino oscillations, - double beta decay, - direct neutrino mass limits, - theory for neutrino masses, neutrino telescopes and ultra-high energy neutrinos, - dark matter searches, - neutrino in astrophysics and cosmology, and - future projects beams and experiments

Neutrino 2004: Collection of Presentations

Energy Technology Data Exchange (ETDEWEB)

NONE

2004-07-01

The scientific program covers the latest developments in neutrino physics, astrophysics and related topics through a set of invited talks and 2 poster sessions. The following issues are addressed: - solar neutrinos, - atmospheric neutrinos, - short and long baseline experiments, - neutrino oscillations, - double beta decay, - direct neutrino mass limits, - theory for neutrino masses, neutrino telescopes and ultra-high energy neutrinos, - dark matter searches, - neutrino in astrophysics and cosmology, and - future projects beams and experiments.

Eighty Kilograms Weight Reduction in a Case of Obstructive Sleep Apnea with Several Comorbidities: Did the Conditions Improve?

Directory of Open Access Journals (Sweden)

Moein Foroughi

2016-05-01

Full Text Available Obstructive sleep apnea (OSA together with metabolic disorders is common in severely obese patients. Weight reduction is considered as a treatment modality in these cases while few of them can succeed in considerable weight loss. Here, we present a severely obese man with body mass index of 54 suffered from OSA, type 2 diabetes, hypothyroidism, and hypertension. He intentionally lost 80 kilograms weight during the 2-year follow-up. Diabetes and hypertension completely resolved with considerable improvement in OSA syndrome after this huge weight reduction.

Abstracts of oral and poster presentations given at the Ascochyta 2012 Workshop, Córdoba, Spain, 22–26 April 2012

Directory of Open Access Journals (Sweden)

Teresa Millan

2013-05-01

Full Text Available The third International Ascochyta Workshop was held in Córdoba, Spain 22 - 26 April 2012. This meeting was attended by 70 participants, and 33 oral presentations, 17 posters and 4 invited speeches were presented dealing with Ascochyta blights of the cool season food legumes (peas, lentils, chickpeas and faba beans. In addition, a special session was held on “Food legumes Research in North Africa”. Abstracts of the oral presentations and the posters of the congress are presented in this issue.

Screening Questionnaires for Obstructive Sleep Apnea: An Updated Systematic Review.

Science.gov (United States)

Amra, Babak; Rahmati, Behzad; Soltaninejad, Forogh; Feizi, Awat

2018-05-01

Obstructive sleep apnea (OSA) is the most common sleep-related breathing disorder and is associated with significant morbidity. We sought to present an updated systematic review of the literature on the accuracy of screening questionnaires for OSA against polysomnography (PSG) as the reference test. Using the main databases (including Medline, Cochrane Database of Systematic Reviews and Scopus) we used a combination of relevant keywords to filter studies published between January 2010 and April 2017. Population-based studies evaluating the accuracy of screening questionnaires for OSA against PSG were included in the review. Thirty-nine studies comprising 18 068 subjects were included. Four screening questionnaires for OSA had been validated in selected studies including the Berlin questionnaire (BQ), STOP-Bang Questionnaire (SBQ), STOP Questionnaire (SQ), and Epworth Sleepiness Scale (ESS). The sensitivity of SBQ in detecting mild (apnea-hypopnea index (AHI) ≥ 5 events/hour) and severe (AHI ≥ 30 events/hour) OSA was higher compared to other screening questionnaires (range from 81.08% to 97.55% and 69.2% to 98.7%, respectively). However, SQ had the highest sensitivity in predicting moderate OSA (AHI ≥ 15 events/hour; range = 41.3% to 100%). SQ and SBQ are reliable tools for screening OSA among sleep clinic patients. Although further validation studies on the screening abilities of these questionnaires on general populations are required.

Genetic diversity and molecular characterization of physic nut ...

African Journals Online (AJOL)

ajl

2013-02-27

Feb 27, 2013 ... 2Department of Plant Science, Federal University of Viçosa, Viçosa, Minas Gerais, Brazil. ... primers were used to characterize toxicity alleles, and none of the accessions presented patterns ... accessions from India (Gupta et al., 2008; Gohil and. Pandya .... ISSR primers, generally low genetic diversity was.

Obstructive Sleep Apnea

Science.gov (United States)

... find out more. Obstructive Sleep Apnea (OSA) Obstructive Sleep Apnea (OSA) Obstructive sleep apnea (OSA) is a ... find out more. Obstructive Sleep Apnea (OSA) Obstructive Sleep Apnea (OSA) Obstructive sleep apnea (OSA) is a ...

Pediatric obstructive sleep apnea and the critical role of oral-facial growth: evidences.

Science.gov (United States)

Huang, Yu-Shu; Guilleminault, Christian

2012-01-01

Review of evidence in support of an oral-facial growth impairment in the development of pediatric sleep apnea in non-obese children. Review of experimental data from infant monkeys with experimentally induced nasal resistance. Review of early historical data in the orthodontic literature indicating the abnormal oral-facial development associated with mouth breathing and nasal resistance. Review of the progressive demonstration of sleep-disordered-breathing (SDB) in children who underwent incomplete treatment of OSA with adenotonsillectomy, and demonstration of abnormal oral-facial anatomy that must often be treated in order for the resolution of OSA. Review of data of long-term recurrence of OSA and indication of oral-facial myofunctional dysfunction in association with the recurrence of OSA. Presentation of prospective data on premature infants and SDB-treated children, supporting the concept of oral-facial hypotonia. Presentation of evidence supporting hypotonia as a primary element in the development of oral-facial anatomic abnormalities leading to abnormal breathing during sleep. Continuous interaction between oral-facial muscle tone, maxillary-mandibular growth and development of SDB. Role of myofunctional reeducation with orthodontics and elimination of upper airway soft tissue in the treatment of non-obese SDB children. Pediatric OSA in non-obese children is a disorder of oral-facial growth.

Influence of environmental variables on the shrub and tree species distribution in two Semideciduous Forest sites in Viçosa, Minas Gerais, Brazil.

Science.gov (United States)

Pinto, Sheila Isabel do C; Martins, Sebastião V; de Barros, Nairam F; Dias, Herly Carlos T; Kunz, Sustanis H

2008-09-01

The floristic variations of shrub and tree components were studied in two sites of Semideciduous Forest, initial forest and mature forest, located in the Mata do Paraíso Forest Reserve, in Viçosa, State of Minas Gerais, Southeastern Brazil, in order to analyze the floristic similarity and the correlations between environmental variables and the distribution of tree species in these forests. Individual trees with a diameter at breast height (DBH) > or = 4.8 cm were sampled in twenty 10 x 30 m plots (10 plots in each site). The plots were distributed systematically at 10 m intervals. The environmental variables analyzed were: the canopy openness and soil chemical and texture characteristics. The two forest sites showed clear differences in the levels of canopy openness and soil fertility, factors that reflect the floristic and successional differences of the shrub and tree component, revealed by the low similarity between these forests by cluster analysis. The canonical correspondence analysis (CCA) of environmental variables and species abundance indicated that the species in these forests studied are distributed under strong influence of canopy openness, moisture and soil fertility.

78 FR 5196 - Notice of Invitation To Participate; Exploration for Coal in Colorado License Application COC-75642

Science.gov (United States)

2013-01-24

...] Notice of Invitation To Participate; Exploration for Coal in Colorado License Application COC-75642... Mineral Leasing Act of 1920, as amended by the Federal Coal Leasing Amendments Act of 1976, and to Bureau..., Colorado. DATES: Any party electing to participate in this exploration program must send written notice to...

Head, Neck, and Oral Cancer

Medline Plus

Full Text Available ... find out more. Obstructive Sleep Apnea (OSA) Obstructive Sleep Apnea (OSA) Obstructive sleep apnea (OSA) is a ... find out more. Obstructive Sleep Apnea (OSA) Obstructive Sleep Apnea (OSA) Obstructive sleep apnea (OSA) is a ...

Administration of Anesthesia

Medline Plus

Full Text Available ... find out more. Obstructive Sleep Apnea (OSA) Obstructive Sleep Apnea (OSA) Obstructive sleep apnea (OSA) is a ... find out more. Obstructive Sleep Apnea (OSA) Obstructive Sleep Apnea (OSA) Obstructive sleep apnea (OSA) is a ...

Corrective Jaw Surgery

Medline Plus

Full Text Available ... find out more. Obstructive Sleep Apnea (OSA) Obstructive Sleep Apnea (OSA) Obstructive sleep apnea (OSA) is a ... find out more. Obstructive Sleep Apnea (OSA) Obstructive Sleep Apnea (OSA) Obstructive sleep apnea (OSA) is a ...

Obstructive Sleep Apnea

Medline Plus

Full Text Available ... find out more. Obstructive Sleep Apnea (OSA) Obstructive Sleep Apnea (OSA) Obstructive sleep apnea (OSA) is a ... find out more. Obstructive Sleep Apnea (OSA) Obstructive Sleep Apnea (OSA) Obstructive sleep apnea (OSA) is a ...

The correlation of anxiety and depression with obstructive sleep apnea syndrome

Directory of Open Access Journals (Sweden)

Fariborz Rezaeitalab

2014-01-01

: 0.001. According to polysomnographic results, we found that the majority of patients suffering from anxiety and chocking (66.7% and 71.4%, respectively had severe OSAS, while only 23.1% of patients with sleepiness had severe OSAS. Conclusion: Our study showed that the frequency of anxiety in OSAS patients is higher than in the general population regardless of the gender. Furthermore, it is more likely that OSAS patients present with anxiety and depression than the typical symptoms.

Workplace worries: a preliminary look at online sexual activities at the office-emerging issues for clinicians and employers.

Science.gov (United States)

Cooper, Al; Safir, Marilyn P; Rosenmann, Amir

2006-02-01

Concerns about the impact of online sexual activities (OSA) on work-life are drastically increasing. This study examined 3,466 respondents who reported OSA, 18.5% of whom reported engaging in OSA at work. They were compared with the 81.5% who engaged in OSA at home, on average time spent in OSA, workplace policies regarding OSA, and relationship status. Two themes were identified and discussed: opportunity and sexual distress. Our findings indicate that participants are cognizant of issues of opportunity (e.g., the OSA from home group was more likely to indicate their workplace has established policies regarding OSA), and privacy, representing an important aspect of this theme (e.g., participants engaging in OSA at work were found to be twice as likely to have extra-marital affairs, compared with the OSA from home group). Secondly, our data suggests that many participants, especially from the OSA at work group, experience OSA-related distress. Engaging in OSA at the workplace may result in decreased productivity, issues of sexual harassment, and concerns about employee well-being. Clearly stated and consistently enforced policies regulating OSA are likely to mitigate workplace OSA. However, a significant minority of employees may have difficulties curbing OSA. Therefore, more sophisticated strategies to deal with workplace OSA should be established. Additional implications of importance for organizations and mental health professionals who support them are discussed.

Invitation cards during pregnancy enhance male partner involvement in prevention of mother to child transmission (PMTCT of human immunodeficiency virus (HIV in Blantyre, Malawi: a randomized controlled open label trial.

Directory of Open Access Journals (Sweden)

Alinane Linda Nyondo

Full Text Available Male involvement (MI is vital for the uptake of Prevention of Mother to Child Transmission (PMTCT of Human Immunodeficiency Virus (HIV interventions. Partner notification (PN is among the strategies identified for MI in PMTCT services. The purpose of this randomized controlled trial was to evaluate the efficacy of an invitation card to the male partners as a strategy for MI in PMTCT services by comparing the proportion of pregnant women that were accompanied by their partners between the intervention and the non-intervention study groups.Pregnant women attending antenatal care without a male partner at South Lunzu and Mpemba health centres in Blantyre, Malawi, were enrolled in the study from June to December 2013. In an intention-to-treat analysis, we compared all participants that were randomized in the invitation card group with the standard of care (SoC group. Risk ratios (RR with 95% confidence intervals (CI were computed to assess the efficacy of the invitation card.Of the 462 randomized women, 65/230 (28.26% of the women in the invitation card group reported to the antenatal care clinic with their partners compared to 44/232 (18.97% women in the SoC group. In an unadjusted intention-to-treat analysis women in the invitation card group were 50% more likely to be accompanied by their male partners than those in the SoC group RR: 1.49 (95% CI: 1.06-2.09; p = 0.02. Our random effects analysis showed that there was no clustering by site of recruitment with an inter cluster correlation coefficient (ICC of 1.98 x 10(-3, (95% CI: 1.78 x10(-7 - 0.96 x 10(-1; p =0.403.An invitation card significantly increased the proportion of women who were accompanied by their male partners for the PMTCT services. An invitation card is a feasible strategy for MI in PMTCT.

76 FR 55701 - Notice of Invitation to Participate; Exploration for Coal in Colorado License Application COC-74895

Science.gov (United States)

2011-09-08

...] Notice of Invitation to Participate; Exploration for Coal in Colorado License Application COC-74895... Mineral Leasing Act of 1920, as amended by the Federal Coal Leasing Amendments Act of 1976, and to Bureau... coal deposits owned by the United States of America in lands located in Routt County, Colorado. DATES...

Mapping Tropical Forest Mosaics with C- and L-band SAR: First Results from Osa Peninsula, Costa Rica

Science.gov (United States)

Pinto, N.; Hensley, S.; Aguilar-Amuchastegui, N.; Broadbent, E. N.; Ahmed, R.

2016-12-01

In tropical countries, economic incentives and improved infrastructure are creating forest mosaics where small-scale farming and industrial plantations are embedded within and potentially replacing native ecosystems. Practices such as agroforestry, slash-and-burn cultivation, and oil palm monocultures bring widely different impacts on carbon stocks. Characterizing these production systems is not only critical to ascribe deforestation to particular drivers, but also essential to understand the impact of macroeconomic scenarios, national policies, and land tenure schemes on carbon fluxes. The last decade has experienced a dramatic improvement in the extent and consistency of tree cover and gross deforestation products from optical imagery. At the same time, recent work shows that Synthetic Aperture Radar (SAR) can complement optical data and reveal structural types that cannot be easily resolved with reflectance measurements alone. While these results demonstrate the validity of sensor fusion methodologies, they typically rely on local classifications or even manual delineation and as such they cannot support large-scale investigations. Furthermore, there have been few attempts to exploit PolInSAR or multiple wavelengths that can provide critical information to resolve natural and anthropogenic land cover types. We report results from our research at Costa Rica's Osa Peninsula. This site is ideal for algorithm development as it includes a highly diverse tropical forest within Corcovado National Park, as well as agroforestry zones, mangroves, and palm plantations. We first integrate SAR backscatter and coherence data from NASA's L-band UAVSAR, JAXA's ALOS/PALSAR, and ESA's Sentinel to produce a map of structural types. Second, we assess whether coherence measurements and PolInSAR retrievals can be used to resolve forest stand differences at 30m resolution and disitinguish between primary and secondary forest sites.

Initial experience with a group presentation of study results to research participants

Directory of Open Access Journals (Sweden)

Bent Stephen

2008-03-01

Full Text Available Abstract Background Despite ethical imperatives, informing research participants about the results of the studies in which they take part is not often performed. This is due, in part, to the costs and burdens of communicating with each participant after publication of the results. Methods Following the closeout and publication of a randomized clinical trial of saw palmetto for treatment of symptoms of benign prostatic hyperplasia, patients were invited back to the research center to participate in a group presentation of the study results. Results Approximately 10% of participants attended one of two presentation sessions. Reaction to the experience of the group presentation was very positive among the attendees. Conclusion A group presentation to research participants is an efficient method of communicating study results to those who desire to be informed and was highly valued by those who attended. Prospectively planning for such presentations and greater scheduling flexibility may result in higher attendance rates. Trial Registration Number Clinicaltrials.gov #NCT00037154

Social Representations of the Artisan Work: Study of Case of an Association of Craftsmen in Viçosa, Minas Gerais – Brazil

Directory of Open Access Journals (Sweden)

Alair Ferreira de Freitas

2010-07-01

Full Text Available This article aims to analyze the social representations of small-scale artisans working for associated Association of Artisans and food producers Homemade of Viçosa, Minas Gerais State-Brazil (Adapac. To this end we have tried to identify and analyse the trajectory of the craftsmen and the reasons for becoming involved with crafts and renditions of the craft for craftsmen linked to this Association. The methodological strategy adopted for the research consisted in case study. As an instrument of data collection, were used to survey participant and application of semi-structured interviews. The method of "content analysis" was used in the Organization and analysis of data. For discussion of the results were defined two categories: (i motivations for the craft and (ii representations of the craft. The results show that this type of work associates itself as the premier opportunity to occupation and income generation found by some members and another as vocation and manual skills. For women the social representations of craft relate the condition of personal satisfaction and possibility of reconciliation with the domestic activities, while for men representations indicate the enhancement of the economic dimension of the craft, distinguishing it from domestic activities.

An Inverse MOOC Model: Small Virtual Field Geology Classes with Many Teachers (Invited)

Science.gov (United States)

De Paor, D. G.; Whitmeyer, S. J.; Bentley, C.

2013-12-01

In the Massive Open Online Courses (MOOCs) mode of instruction, one or a small group of collaborating instructors lecture online to a large (often extremely large) number of students. We are experimenting with an inverse concept: an online classroom in which a small group of collaborating students are taught by dozens of collaborating instructors. This experiment is part of a new NSF TUES Type 3 project titled 'Google Earth for Onsite and Distance Education (GEODE).' Among the goals of the project are the development of an online course called the 'Grand Tour.' We are inviting dozens of colleagues to record virtual field trips (VFTs) and upload them to Google Earth. Students enrolled in the course will be assigned to a small group and tasked with a research project--for example to write a report on foreland thrust belts. They will select a small subset of available VFTs to follow and will be scaffolded by virtual specimens, emergent cross sections, analytical simulations (virtual tricorders), and a game style environment. Instant feedback based on auto-logging will enable adaptive learning. The design is suited to both onsite and distance education and will facilitate access to iconic geologic sites around the world to persons with mobility constraints. We invite input from the community to help guide the design phase of this project. Prototypes of the above-listed learning resources have already been developed and are freely available at http://www.DigitalPlanet.org.

CERN is celebrating its anniversary - invite your neighbours!

CERN Document Server

Corinne Pralavorio

2014-01-01

On 24 and 25 May 2014, CERN will be organising a weekend of discovery to celebrate its 60th anniversary with its (our) neighbours. Come and help us to welcome them as a volunteer!   CERN is celebrating 60 years since its establishment - 60 years during which the region and the Laboratory have developed strong links. To celebrate this collaboration, two days of visits and activities for everyone living in the region are being organised. Underground visits to the CMS detector in Cessy, the LHCb detector in Ferney-Voltaire and the LHC machine in Échenevex will be held throughout the weekend. Some 6,000 visitors are expected to make the most of one of the last chances to visit the underground installations before the LHC is restarted next year. These visits are open only to people aged 12 years and over and are by reservation only. Members of the public are also invited to take part in fun activities at the site of the CMS experiment in Cessy. The programme includes demonstrations an...

Invitational Rhetoric and the Case for Service Learning

Directory of Open Access Journals (Sweden)

Christina L. Hicks-Goldston

2011-10-01

Full Text Available This research argues for repositioning Service Learning as a necessary part of public education, with the transformative goal of empowered communities operating in a social-collaborative framework from communities dependent on overburdened state and local government programs and services. Such repositioning depends on recognition of Service Learning as a means of providing that preparation. To “mainstream” Service Learning, this research proposes two initiatives: (a Foster the idea of the Service Learning experience as citizenship/community building by associating the experience with embedded cultural values and (b apply Invitational Rhetoric in persuading students and parents to view Service Learning as something other than imposed servitude or social consciousness for a grade. Service Learning has proven to be successful in changing students’ attitudes about their place in society. If Service Learning were a part of the common educational core, the potential for repositioning its value to citizenry would be highly expanded. Because many communities lack access to education and training for the citizenry, Service Learning could supply that link to empowerment.

Gender stereotypes and linguistic sexism present in books in educational context for children

Directory of Open Access Journals (Sweden)

Daniela Finco

2018-05-01

Full Text Available In Italy, since the 1970s, there has been a significant debate on the studies on linguistic sexism that have contributed to the problematization of the presence of gender stereotypes in children's literature. This article presents a historical reconstruction of the debate developed in Italy in the last forty years. The debate showed the importance of problematizing the patterns of identity and behavior transmitted through reading in educational contexts for children. This context also led to the drafting of the Polite Project, which invites editors to be respectful with gender differences, both text and images. It presents important research on the problem of the presence of stereotyped messages of gender present in books for children and the changes that have occurred throughout this process.

Role of spousal involvement in continuous positive airway pressure (CPAP adherence in patients with obstructive sleep apnea (OSA

Directory of Open Access Journals (Sweden)

Batool-Anwar S

2017-05-01

Full Text Available Introduction: Little is known about the impact of spousal involvement on continuous positive airway pressure (CPAP adherence. The aim of this study was to determine whether spouse involvement affects adherence with CPAP therapy, and how this association varies with gender. Methods: 194 subjects recruited from Apnea Positive Pressure Long Term Efficacy Study (APPLES completed the Dyadic Adjustment Scale (DAS. The majority of participants were Caucasian (83%, and males (73%, with mean age of 56 years, mean BMI of 31 kg/m2. & 62% had severe OSA. The DAS is a validated 32-item self-report instrument measuring dyadic consensus, satisfaction, cohesion, and affectional expression. A high score in the DAS is indicative of a person’s adjustment to the marriage. Additionally, questions related to spouse involvement with general health and CPAP use were asked. CPAP use was downloaded from the device and self-report, and compliance was defined as usage > 4 h per night. Results: There were no significant differences in overall marital quality between the compliant and noncompliant subjects. However, level of spousal involvement was associated with increased CPAP adherence at 6 months (p=0.01. After stratifying for gender these results were significant only among males (p=0.03. Three years after completing APPLES, level of spousal involvement was not associated with CPAP compliance even after gender stratification. Conclusion: Spousal involvement is important in determining CPAP compliance in males in the 1st 6 months after initiation of therapy but is not predictive of longer-term adherence. Involvement of the spouse should be considered an integral part of CPAP initiation procedures.

A Preliminary Efficacy and Feasibility of an Obstructive Sleep Apnea Educational Intervention in Oman

Science.gov (United States)

Al Mezeini, Khamis Abdallah

Background: Obstructive sleep apnea (OSA) is chronic disorder that contributes to multiple physiological and psychological conditions. Obstructive sleep apnea contributes to high rates of morbidity and mortality and has substantial impacts on both health care costs and the quality of life for affected individuals and their families. Healthcare providers - particularly primary health care nurses - are ideally situated to interrupt the cascading consequences of OSA if they are equipped with evidence-based knowledge about the disease process and appropriate methods for screening, education, and preventive interventions. Purpose: The purpose of the study was to test the preliminary efficacy and feasibility of an online health educational intervention on the knowledge and attitudes of OSA among primary health care nurses in Oman. Methods: This study was designed to assess the preliminary efficacy and feasibility of an online educational program on OSA by randomly assigning subjects to either a treatment (OSA content) or attention control (diabetes content) group. At baseline, the OSA knowledge and attitudes of both groups were assessed by the Obstructive Sleep Apnea Knowledge and Attitudes (OSAKA) questionnaire; both groups also completed the Diabetes Basic Knowledge Test (DBKT) to use for control comparisons. Following randomization, the intervention group viewed a 15-minute narrated video on "Brief Introduction to OSA for Omani Nurses" and the control group viewed a similarly formatted 15-minute narrated video on diabetes. The intent was for the subjects in both groups to complete a posttest that included both the OSAKA and DBKT instruments; however, due to a programming error, the software did not present the DBKT to the intervention subjects and did not present the OSAKA instrument to the control subjects as intended. Therefore, the results describe the findings from a one-group, pretest-posttest intervention study to assess the preliminary efficacy and feasibility

ALL MEMBERS AND BENEFICIARIES OF THE PENSION FUND ARE INVITED TO ATTEND THE ANNUAL GENERAL ASSEMBLY

CERN Multimedia

2000-01-01

Annual General Assembly to be held in the CERN Auditorium on Wednesday 4 October 2000 at 14.30 hrs The Agenda comprises: 1. Opening Remarks: - P. Levaux 2. The Swiss provident system: - C. Cuénoud recent trends 3. Annual Report 1999: - C. Cuénoud Presentation and results Copies of the Report are available from divisional secretariats. 4. Pension Fund’s investment policy and performance: - G. Maurin 5. Questions from members and beneficiaries Persons wishing to ask questions are encouraged to submit them, where possible, in writing in advance, addressed to Mr C. Cuénoud, Administrator of the Fund. 5. Conclusions P. Levaux As usual, participants are invited to drinks after the assembly. NB The minutes of the 1999 General Assembly are available from the Administration of the Fund (tel.(+4122)767 9194; e-mail Graziella.Praire@cern.ch) SOME ASPECTS OF THE FUND’S ACTIVITIES IN 1999 The Governing Board (at 31 December 1999) Members Appointed by C. Bovet (Alternate: E. Chiaveri...

The Lung Screen Uptake Trial (LSUT): protocol for a randomised controlled demonstration lung cancer screening pilot testing a targeted invitation strategy for high risk and 'hard-to-reach' patients.

Science.gov (United States)

Quaife, Samantha L; Ruparel, Mamta; Beeken, Rebecca J; McEwen, Andy; Isitt, John; Nolan, Gary; Sennett, Karen; Baldwin, David R; Duffy, Stephen W; Janes, Samuel M; Wardle, Jane

2016-04-20

Participation in low-dose CT (LDCT) lung cancer screening offered in the trial context has been poor, especially among smokers from socioeconomically deprived backgrounds; a group for whom the risk-benefit ratio is improved due to their high risk of lung cancer. Attracting high risk participants is essential to the success and equity of any future screening programme. This study will investigate whether the observed low and biased uptake of screening can be improved using a targeted invitation strategy. A randomised controlled trial design will be used to test whether targeted invitation materials are effective at improving engagement with an offer of lung cancer screening for high risk candidates. Two thousand patients aged 60-75 and recorded as a smoker within the last five years by their GP, will be identified from primary care records and individually randomised to receive either intervention invitation materials (which take a targeted, stepped and low burden approach to information provision prior to the appointment) or control invitation materials. The primary outcome is uptake of a nurse-led 'lung health check' hospital appointment, during which patients will be offered a spirometry test, an exhaled carbon monoxide (CO) reading, and an LDCT if eligible. Initial data on demographics (i.e. age, sex, ethnicity, deprivation score) and smoking status will be collected in primary care and analysed to explore differences between attenders and non-attenders with respect to invitation group. Those who attend the lung health check will have further data on smoking collected during their appointment (including pack-year history, nicotine dependence and confidence to quit). Secondary outcomes will include willingness to be screened, uptake of LDCT and measures of informed decision-making to ensure the latter is not compromised by either invitation strategy. If effective at improving informed uptake of screening and reducing bias in participation, this invitation

Machine learning concepts in coherent optical communication systems

DEFF Research Database (Denmark)

Zibar, Darko; Schäffer, Christian G.

2014-01-01

Powerful statistical signal processing methods, used by the machine learning community, are addressed and linked to current problems in coherent optical communication. Bayesian filtering methods are presented and applied for nonlinear dynamic state tracking. © 2014 OSA.......Powerful statistical signal processing methods, used by the machine learning community, are addressed and linked to current problems in coherent optical communication. Bayesian filtering methods are presented and applied for nonlinear dynamic state tracking. © 2014 OSA....

Patrones de riqueza altitudinal de Papilionidae, Pieridae y Nymphalidae (Lepidoptera: Rhopalocera en áreas montañosas de México

Directory of Open Access Journals (Sweden)

David

2013-09-01

Full Text Available Las mariposas diurnas integran uno de los grupos más utilizados para el reconocimiento y monitoreo de la diversidad de una biota. Se realizó un estudio comparativo de las faunas de mariposas de las familias Papilionidae, Pieridae y Nymphalidae de cinco áreas montañosas de México, situadas en las vertientes Atlántico y Pacífico: las sierras de Atoyac de Álvarez, Manantlán, Juárez, y las áreas de Teocelo-Xalapa y la región Loxicha, con un total de 34 localidades representativas de los cinco transectos altitudinales, que comprenden de los 300 a los 3 100m de altitud. Se observó una tendencia general a la disminución de la riqueza con la altitud. Se analizó la similitud entre el total de localidades mediante el índice de Sørensen, diferenciándose en primer lugar las dos estaciones de elevaciones superiores (sobre los 2 500msnm, caracterizadas por pobres lepidóptero-faunas. En el grupo principal (32 sitios las principales agrupaciones se dan de acuerdo, en primer lugar, a la pertenencia a la vertiente pacífica o atlántica, evento más histórico que ecológico y, después, las estaciones de una misma sierra o según tres diferentes pisos altitudinales, que se caracterizan de acuerdo con los táxones predominantes.

Hybrid III-V Silicon Lasers

Science.gov (United States)

Bowers, John

2014-03-01

Abstract: A number of important breakthroughs in the past decade have focused attention on Si as a photonic platform. We review here recent progress in this field, focusing on efforts to make lasers, amplifiers, modulators and photodetectors on or in silicon. We also describe optimum quantum well design and distributed feedback cavity design to reduce the threshold and increase the efficiency and power output. The impact active silicon photonic integrated circuits could have on interconnects, telecommunications and on silicon electronics is reviewed. Biography: John Bowers holds the Fred Kavli Chair in Nanotechnology, and is the Director of the Institute for Energy Efficiency and a Professor in the Departments of Electrical and Computer Engineering and Materials at UCSB. He is a cofounder of Aurrion, Aerius Photonics and Calient Networks. Dr. Bowers received his M.S. and Ph.D. degrees from Stanford University and worked for AT&T Bell Laboratories and Honeywell before joining UC Santa Barbara. Dr. Bowers is a member of the National Academy of Engineering and a fellow of the IEEE, OSA and the American Physical Society. He is a recipient of the OSA/IEEE Tyndall Award, the OSA Holonyak Prize, the IEEE LEOS William Streifer Award and the South Coast Business and Technology Entrepreneur of the Year Award. He and coworkers received the EE Times Annual Creativity in Electronics (ACE) Award for Most Promising Technology for the hybrid silicon laser in 2007. Bowers' research is primarily in optoelectronics and photonic integrated circuits. He has published ten book chapters, 600 journal papers, 900 conference papers and has received 54 patents. He has published 180 invited papers and conference papers, and given 16 plenary talks at conferences. As well as Chong Zhang.

Ensemble Kalman filtering with one-step-ahead smoothing

KAUST Repository

Raboudi, Naila F.

2018-01-11

The ensemble Kalman filter (EnKF) is widely used for sequential data assimilation. It operates as a succession of forecast and analysis steps. In realistic large-scale applications, EnKFs are implemented with small ensembles and poorly known model error statistics. This limits their representativeness of the background error covariances and, thus, their performance. This work explores the efficiency of the one-step-ahead (OSA) smoothing formulation of the Bayesian filtering problem to enhance the data assimilation performance of EnKFs. Filtering with OSA smoothing introduces an updated step with future observations, conditioning the ensemble sampling with more information. This should provide an improved background ensemble in the analysis step, which may help to mitigate the suboptimal character of EnKF-based methods. Here, the authors demonstrate the efficiency of a stochastic EnKF with OSA smoothing for state estimation. They then introduce a deterministic-like EnKF-OSA based on the singular evolutive interpolated ensemble Kalman (SEIK) filter. The authors show that the proposed SEIK-OSA outperforms both SEIK, as it efficiently exploits the data twice, and the stochastic EnKF-OSA, as it avoids observational error undersampling. They present extensive assimilation results from numerical experiments conducted with the Lorenz-96 model to demonstrate SEIK-OSA’s capabilities.

Obstructive Sleep Apnea and Cardiovascular Disease - A New Target for Treatment.

Science.gov (United States)

Schillaci, Giuseppe; Battista, Francesca; Fiorenzano, Giuseppe; Basili, Maria Cristina; Crapa, Mariano; Alrashdi, Yahya; Pucci, Giacomo

2015-01-01

Obstructive sleep apnea (OSA) is characterized by recurrent episodes of partial (hypopnea) or complete interruption (apnea) in breathing during sleep due to airway collapse in the oral or pharyngeal region. Prospective studies have established the adverse cardiovascular consequences of OSA, including an increased risk for developing hypertension, coronary artery disease, stroke, and heart failure. However, more studies are needed to better assess the impact of OSA, and possible benefit of treatment with continuous positive airway pressure (CPAP) on cardiovascular mortality. The leading pathophysiological mechanisms involved in the changes triggered by OSA include intermittent hypoxemia and re-oxygenation, arousals and changes in intrathoracic pressure. Hypertension is strongly related with activation of the sympathetic nervous system, stimulation of the renin-angiotensin-aldosterone system and endothelial dysfunction. OSA should be suspected in hypertensive individuals, particularly in patients with resistant hypertension. CPAP treatment reduces blood pressure, and its effects are more pronounced in patients with high baseline blood pressure and elevated treatment compliance. At present, no clear evidence supports CPAP treatment for primary or secondary cardiovascular disease prevention.

microRNAs targeting DEAD-box helicases are involved in salinity stress response in rice (Oryza sativa L.

Directory of Open Access Journals (Sweden)

Macovei Anca

2012-10-01

Full Text Available Abstract Background Rice (Oryza sativa L., one of the most important food crop in the world, is considered to be a salt-sensitive crop. Excess levels of salt adversely affect all the major metabolic activities, including cell wall damage, cytoplasmic lysis and genomic stability. In order to cope with salt stress, plants have evolved high degrees of developmental plasticity, including adaptation via cascades of molecular networks and changes in gene expression profiles. Posttranscriptional regulation, through the activity of microRNAs, also plays an important role in the plant response to salinity conditions. MicroRNAs are small endogenous RNAs that modulate gene expression and are involved in the most essential physiological processes, including plant development and adaptation to environmental changes. Results In the present study, we investigated the expression profiles of osa-MIR414, osa-MIR408 and osa-MIR164e along with their targeted genes, under salinity stress conditions in wild type and transgenic rice plants ectopically expressing the PDH45 (Pea DNA Helicase gene. The present miRNAs were predicted to target the OsABP (ATP-Binding Protein, OsDSHCT (DOB1/SK12/helY-like DEAD-box Helicase and OsDBH (DEAD-Box Helicase genes, included in the DEAD-box helicase family. An in silico characterization of the proteins was performed and the miRNAs predicted targets were validated by RLM-5′RACE. The qRT-PCR analysis showed that the OsABP, OsDBH and OsDSHCT genes were up-regulated in response to 100 and 200 mM NaCl treatments. The present study also highlighted an increased accumulation of the gene transcripts in wild type plants, with the exception of the OsABP mRNA which showed the highest level (15.1-fold change compared to control in the transgenic plants treated with 200 mM NaCl. Salinity treatments also affected the expression of osa-MIR414, osa-MIR164e and osa-MIR408, found to be significantly down-regulated, although the changes in mi

Identifying obstructive sleep apnea after stroke/TIA: evaluating four simple screening tools.

Science.gov (United States)

Boulos, Mark I; Wan, Anthony; Im, James; Elias, Sara; Frankul, Fadi; Atalla, Mina; Black, Sandra E; Basile, Vincenzo S; Sundaram, Arun; Hopyan, Julia J; Boyle, Karl; Gladstone, David J; Murray, Brian J; Swartz, Richard H

2016-05-01

Despite its high prevalence and unfavorable clinical consequences, obstructive sleep apnea (OSA) often remains underappreciated after cerebrovascular events. The purpose of our study was to evaluate the clinical utility of four simple paper-based screening tools for excluding OSA after stroke or transient ischemic attack (TIA). Sixty-nine inpatients and outpatients with stroke or TIA during the past 180 days completed the 4-Variable screening tool (4V), STOP-BAG questionnaire (ie, STOP-BANG questionnaire without the neck circumference measurement), Berlin questionnaire, and the Sleep Obstructive apnea score optimized for Stroke (SOS). They subsequently underwent objective testing using a portable sleep monitoring device. Cutoffs were selected to maximize sensitivity and exclude OSA (AHI ≥ 10) in ≥10% of the cohort. The mean age was 68.3 ± 14.2 years and 47.8% were male. Thirty-two patients (46.4%) were found to have OSA. Male sex, body mass index (BMI), and atrial fibrillation were independent predictors of OSA. Among the screening tools, the 4V had the greatest area under the curve (AUC) of 0.688 (p = 0.007); the sensitivity was 96.9% for a cutoff of stroke/TIA. Due to the atypical presentation of poststroke/TIA OSA, these tools are only moderately predictive; objective testing should still be used for OSA diagnosis in this population. Copyright © 2016 Elsevier B.V. All rights reserved.

Calidad nutricional y digestibilidad in situ de ensilajes de cuatro leñosas forrajeras

Directory of Open Access Journals (Sweden)

María Ligia Roa

Full Text Available Se evaluó el efecto del tiempo de conservación en la calidad nutricional y la digestibilidad in situ de ensilajes de cuatro plantas leñosas forrajeras: Cratylia argentea (T1, Hibiscus rosa-sinensis (T2, Trichanthera gigantea (T3 y Tithonia diversifolia (T4. Las plantas fueron podadas a los seis meses de establecidas y a los tres meses de rebrote, y se utilizaron las hojas y ramas tiernas pequeñas para confeccionar 64 silos de 10 kg, en bolsas plásticas. Cada tiempo de conservación (0, 30, 60 y 90 días tuvo cuatro repeticiones. Para calcular la digestibilidad de la MS, el NT y la FDN y los parámetros de la digestibilidad efectiva (DE, se utilizaron cuatro bovinos fistulados en el rumen, distribuidos en un diseño cuadrado latino 4 x 4. Los ensilajes presentaron aspecto y olor agradables, con pH entre 4,2 y 4,6 y nitrógeno amoniacal menor que 1 %. El porcentaje de NT fue mayor para T1 (2,52 y T2 (2,43, y este nutriente se redujo hasta los 90 días. La DE de la MS, el NT y la FDN fue superior (p < 0,05 en T2, con tendencia a disminuir con el tiempo de conservación (90 días. Este mismo comportamiento presentaron las fracciones A, B y c. El mayor contenido de lignina se resentó en T3 (5,45 % y T4 (5,60 %, indicador que afectó de manera negativa la cinética ruminal. La disminución de la calidad nutricional y la digestibilidad por el tiempo de conservación fue menor para T2 y T3. Se concluye que las propiedades órganolepticas de los ensilajes fueron óptimas, el nitrógeno amoniacal no superó el 1% y el ácido láctico varió entre 1,0 y 3,6 %; mientras que el tiempo afectó en menor grado la composición nutricional del ensilaje de H. rosa-sinensis, con respecto a las otras forrajeras. Se recomienda ensilar para la época de seca y utilizar los ensilajes antes de los 60 días de conservación.

Genomic instability and telomere fusion of canine osteosarcoma cells.

Directory of Open Access Journals (Sweden)

Junko Maeda

Full Text Available Canine osteosarcoma (OSA is known to present with highly variable and chaotic karyotypes, including hypodiploidy, hyperdiploidy, and increased numbers of metacentric chromosomes. The spectrum of genomic instabilities in canine OSA has significantly augmented the difficulty in clearly defining the biological and clinical significance of the observed cytogenetic abnormalities. In this study, eight canine OSA cell lines were used to investigate telomere fusions by fluorescence in situ hybridization (FISH using a peptide nucleotide acid probe. We characterized each cell line by classical cytogenetic studies and cellular phenotypes including telomere associated factors and then evaluated correlations from this data. All eight canine OSA cell lines displayed increased abnormal metacentric chromosomes and exhibited numerous telomere fusions and interstitial telomeric signals. Also, as evidence of unstable telomeres, colocalization of γ-H2AX and telomere signals in interphase cells was observed. Each cell line was characterized by a combination of data representing cellular doubling time, DNA content, chromosome number, metacentric chromosome frequency, telomere signal level, cellular radiosensitivity, and DNA-PKcs protein expression level. We have also studied primary cultures from 10 spontaneous canine OSAs. Based on the observation of telomere aberrations in those primary cell cultures, we are reasonably certain that our observations in cell lines are not an artifact of prolonged culture. A correlation between telomere fusions and the other characteristics analyzed in our study could not be identified. However, it is important to note that all of the canine OSA samples exhibiting telomere fusion utilized in our study were telomerase positive. Pending further research regarding telomerase negative canine OSA cell lines, our findings may suggest telomere fusions can potentially serve as a novel marker for canine OSA.

Pediatric Obstructive Sleep Apnea and the critical role of oral-facial growth: evidences

Directory of Open Access Journals (Sweden)

Christian eGuilleminault

2013-01-01

Full Text Available Aims: Review of evidence in support of an oral-facial growth impairment in the development of pediatric sleep apnea in non-obese childrenMethod: Review of experimental data from infant monkeys with experimentally induced nasal resistance. Review of early historical data in the orthodontic literature indicating the abnormal oral-facial development associated with mouth breathing and nasal resistance. Review of the progressive demonstration of sleep disordered breathing in children who underwent incomplete treatment of OSA with adenotonsillectomy, and demonstration of abnormal oral-facial anatomy that must often to be treated in order for the resolution of OSA. Review of long term recurrence data on OSA and indication of oral-facial myofunctional dysfunction in association with the recurrence of OSA. Results: Presentation of prospective data on premature infants and sleep-disordered-breathing (SDB-treated children, supporting the concept of oral-facial hypotonia. Presentation of evidence supporting hypotonia as a primary element in the development of oral-facial anatomic abnormalities leading to abnormal breathing during sleep. Continuous interaction between oral facial muscle tone, maxillary-mandibular growth and development of SDB. Role of myofunctional re-education with orthodontics and elimination of upper airway soft tissue in the treatment of non-obese SDB children. Conclusion: Pediatric OSA in non-obese children is a disorder of oral facial growth.

Clinical, polysomnographic, and CPAP titration features of obstructive sleep apnea: Mixed versus purely obstructive type.

Science.gov (United States)

Lee, Sang-Ahm; Lee, Gha-Hyun; Chung, Yoo-Sam; Kim, Woo Sung

2015-08-15

To determine whether obstructive sleep apnea syndrome (OSAS) patients with mixed sleep apnea (MSA) have different clinical, polysomnographic, and continuous positive airway pressure (CPAP) titration findings compared to OSAS patients without MSA. We retrospectively reviewed the records of OSAS patients who had undergone CPAP titration and categorized them into pure-OSA and mixed-OSA groups. Demographic features, daytime sleepiness, and apnea severity were compared between the two groups using univariate and multivariate analyses. CPAP titration findings were also compared between the two groups. One hundred and ninety-five subjects (n=126 pure-OSA; n=69 mixed-OSA) were included in the analysis. Compared to the pure-OSA group, the mixed-OSA group had a higher percentage of males (p=0.003) and a higher body mass index (p=0.044), Epworth Sleepiness Scale score (p=0.028), and apnea-hypopnea index (AHI) (ptitration, and a higher titrated pressure than the pure-OSA group. Severe OSA, older age, male sex, obesity, and daytime sleepiness were related to mixed-OSA. Complex sleep apnea, less optimal titration, and a higher titrated CPAP were also associated with MSA in OSAS patients. Copyright © 2015 Elsevier B.V. All rights reserved.

An Invitation to Open Innovation in Malaria Drug Discovery: 47 Quality Starting Points from the TCAMS.

Science.gov (United States)

Calderón, Félix; Barros, David; Bueno, José María; Coterón, José Miguel; Fernández, Esther; Gamo, Francisco Javier; Lavandera, José Luís; León, María Luisa; Macdonald, Simon J F; Mallo, Araceli; Manzano, Pilar; Porras, Esther; Fiandor, José María; Castro, Julia

2011-10-13

In 2010, GlaxoSmithKline published the structures of 13533 chemical starting points for antimalarial lead identification. By using an agglomerative structural clustering technique followed by computational filters such as antimalarial activity, physicochemical properties, and dissimilarity to known antimalarial structures, we have identified 47 starting points for lead optimization. Their structures are provided. We invite potential collaborators to work with us to discover new clinical candidates.

De-Virtualizing Social Events: Understanding the Gap between Online and Offline Participation for Event Invitations

OpenAIRE

Huang, Ai-Ju; Wang, Hao-Chuan; Yuan, Chien Wen

2013-01-01

One growing use of computer-based communication media is for gathering people to initiate or sustain social events. Although the use of computer-mediated communication and social network sites such as Facebook for event promotion is becoming popular, online participation in an event does not always translate to offline attendance. In this paper, we report on an interview study of 31 participants that examines how people handle online event invitations and what influences their online and offl...

Obstructive sleep apnea combined dyslipidemia render additive effect on increasing atherosclerotic cardiovascular diseases prevalence.

Science.gov (United States)

Cao, Zhiyong; Zhang, Ping; He, Zhiqing; Yang, Jing; Liang, Chun; Ren, Yusheng; Wu, Zonggui

2016-05-26

Current study was designed to investigate the effects of obstructive sleep apnea (OSA) combined dyslipidemia on the prevalence of atherosclerotic cardiovascular diseases (ASCVD). This was a cross-sectional study and subjects with documented dyslipidemia and without previous diagnosis of OSA were enrolled. Polysomnography was applied to evaluate apnea-hypopnea index (AHI). Based on AHI value, subjects were classified into four groups: without OSA, mild, moderate and severe OSA groups. Clinical characteristics and laboratory examination data were recorded. Relationship between AHI event and lipid profiles was analyzed, and logistic regression analysis was used to evaluate the effects of OSA combined dyslipidemia on ASCVD prevalence. Totally 248 subjects with dyslipidemia were enrolled. Compared to the other 3 groups, subjects with severe OSA were older, male predominant and had higher smoking rate. In addition, subjects with severe OSA had higher body mass index, waist-hip ratio, blood pressure, and higher rates of overweight and obesity. Serum levels of fasting plasma glucose, glycated hemoglobin, LDL-C and CRP were all significantly higher. ASCVD prevalence was considerably higher in subjects with severe OSA. AHI event in the severe OSA group was up to 35.4 ± 5.1 events per hour which was significantly higher than the other groups (P dyslipidemia plus no-OSA group (reference group), OSA enhanced ASCVD risk in subjects with dyslipidemia, regardless of OSA severity. After extensively adjusted for confounding variables, the odds of dyslipidemia plus mild-OSA was reduced to insignificance. While the effects of moderate- and severe-OSA on promoting ASCVD risk in subjects with dyslipidemia remained significant, with severe-OSA most prominent (odds ratio: 1.52, 95% confidence interval: 1.13-2.02). OSA combined dyslipidemia conferred additive adverse effects on cardiovascular system, with severe-OSA most prominent.

Position paper by Canadian dental sleep medicine professionals on the role of different health care professionals in managing obstructive sleep apnea and snoring with oral appliances.

Science.gov (United States)

Gauthier, Luc; Almeida, Fernanda; Arcache, Jean-Patrick; Ashton-McGregor, Catherine; Coté, David; Driver, Helen S; Ferguson, Kathleen A; Lavigne, Gilles J; Martin, Philippe; Masse, Jean-François; Morisson, Florence; Pancer, Jeffrey; Samuels, Charles Harry; Schachter, Maurice; Sériès, Frédéric; Sullivan, Glendon Edward

2012-01-01

The present Canadian position paper contains recommendations for the management by dentists of sleep-disordered breathing in adults with the use of oral appliances (OAs) as a treatment option for snoring and obstructive sleep apnea (OSA). The recommendations are based on literature reviews and expert panel consensus. OAs offer an effective, first-line treatment option for patients with mild to moderate OSA who prefer an OA to continuous positive airway pressure (CPAP) therapy, or for severe OSA patients who cannot tolerate CPAP, are inappropriate candidates for CPAP or who have failed CPAP treatment attempts. The purpose of the present position paper is to guide interdisciplinary teamwork (sleep physicians and sleep dentists) and to clarify the role of each professional in the management of OA therapy. The diagnosis of OSA should always be made by a physician, and OAs should be fitted by a qualified dentist who is trained and experienced in dental sleep medicine. Follow-up assessment by the referring physician and polysomnography or sleep studies are required to verify treatment efficacy. The present article emphasizes the need for a team approach to OA therapy and provides treatment guidelines for dentists trained in dental sleep medicine. Many of the dentists and sleep physicians who contributed to the preparation of the present article are members of the Canadian Sleep Society and the authors reached a consensus based on the current literature.

Non drowsy obstructive sleep apnea as a potential cause of resistant hypertension: a case report

Directory of Open Access Journals (Sweden)

Mirrakhimov Aibek E

2012-05-01

Full Text Available Abstract Background Obstructive sleep apnea (OSA and arterial hypertension (AH are common and underrecognized medical disorders. OSA is a potential risk factor for the development of AH and/or may act as a factor complicating AH management. The symptoms of excessive daytime sleepiness (EDS are considered essential for the initiation of continuous positive airway pressure (CPAP therapy, which is a first line treatment of OSA. The medical literature and practice is controversial about the treatment of people with asymptomatic OSA. Thus, OSA patients without EDS may be left at increased cardiovascular risk. Case presentation The report presents a case of 42year old Asian woman with symptoms of heart failure and angina like chest pain upon admission. She didnt experience symptoms of EDS, and the Epworth Sleepiness Scale was seven points. Snoring was reported on direct questioning. The patient had prior medical history of three unsuccessful pregnancies complicated by gestational AH and preeclampsia with C-section during the last pregnancy. The admission blood pressure (BP was 200/120mm Hg. The patients treatment regimen consisted of five hypotensive medications including diuretic. However, a target BP wasnt achieved in about one and half month. The patient was offered to undergo a polysomnography (PSG study, which she rejected. One month after discharge the PSG study was done, and this showed an apnea-hypopnea index (AHI of 46 events per hour. CPAP therapy was initiated with a pressure of 11H20cm. After 2months of compliant CPAP use, adherence to pharmacologic regimen and lifestyle modifications the patients BP decreased to 134/82mm Hg. Conclusions OSA and AH are common and often underdiagnosed medical disorders independently imposing excessive cardiovascular risk on a diseased subject. When two conditions coexist the cardiovascular risk is likely much greater. This case highlights a possible clinical phenotype of OSA without EDS and its association

ENS RRFM 2000. Transactions. Oral presentations and posters

Energy Technology Data Exchange (ETDEWEB)

NONE

2000-07-01

The four sessions at the fourth international topical meeting on research reactor fuel management dealt with the following topics: fissile materials supply, reactor operation and fuel safety; back-end options and transportation; future of research reactors. In this book the text of the invited and contributed papers as well as of the posters are included.

ENS RRFM 2000. Transactions. Oral presentations and posters

International Nuclear Information System (INIS)

2000-01-01

The four sessions at the fourth international topical meeting on research reactor fuel management dealt with the following topics: fissile materials supply, reactor operation and fuel safety; back-end options and transportation; future of research reactors. In this book the text of the invited and contributed papers as well as of the posters are included

Invitation to the IAEA FR17 Conference on Fast Reactors, Russia, 2017

International Nuclear Information System (INIS)

Rachkov, V.

2013-01-01

Russian Federation has a large successful experience of peaceful application of nuclear power and it is a leader in development of fast reactors that permit to create sustainable and safe base for future world nuclear power. Russian Government approved in 2010 a Federal Target Program “Nuclear power technologies of a new generation for period of 2010-2015 and with outlook to 2020” aimed at creation of new technological platform for future nuclear power based on fast reactors. State Atomic Energy Corporation “Rosatom” supports activities of the IAEA on strengthening international collaboration on fast reactors and invites IAEA to host next FR17 Conference on FRs in Russia in 2017

Relative Over Population and the “New Social Question”: an Invitation to Marxian Categories

Directory of Open Access Journals (Sweden)

Ednéia Alves de Oliveira

2010-01-01

Full Text Available This article analyzes the mystified concept that poverty has acquired in the current stage of capitalist accumulation. It relates the growth of overpopulation to a critical perspective in which the conflict between labor and capital is an essential condition for the emergence and permanence of this overpopulation. It looks at the relationship of the general law of capitalist accumulation and at transformations in the order of capital, and then at the naturalized approach that the social question has acquired in this context, inviting a review of Marxian categories.

Towards an understanding of Internet-based problem shopping behaviour: The concept of online shopping addiction and its proposed predictors

Science.gov (United States)

ROSE, SUSAN; DHANDAYUDHAM, ARUN

2014-01-01

Background: Compulsive and addictive forms of consumption and buying behaviour have been researched in both business and medical literature. Shopping enabled via the Internet now introduces new features to the shopping experience that translate to positive benefits for the shopper. Evidence now suggests that this new shopping experience may lead to problematic online shopping behaviour. This paper provides a theoretical review of the literature relevant to online shopping addiction (OSA). Based on this selective review, a conceptual model of OSA is presented. Method: The selective review of the literature draws on searches within databases relevant to both clinical and consumer behaviour literature including EBSCO, ABI Pro-Quest, Web of Science – Social Citations Index, Medline, PsycINFO and Pubmed. The article reviews current thinking on problematic, and specifically addictive, behaviour in relation to online shopping. Results: The review of the literature enables the extension of existing knowledge into the Internet-context. A conceptual model of OSA is developed with theoretical support provided for the inclusion of 7 predictor variables: low self-esteem, low self-regulation; negative emotional state; enjoyment; female gender; social anonymity and cognitive overload. The construct of OSA is defined and six component criteria of OSA are proposed based on established technological addiction criteria. Conclusions: Current Internet-based shopping experiences may trigger problematic behaviours which can be classified on a spectrum which at the extreme end incorporates OSA. The development of a conceptual model provides a basis for the future measurement and testing of proposed predictor variables and the outcome variable OSA. PMID:25215218

Towards an understanding of Internet-based problem shopping behaviour: The concept of online shopping addiction and its proposed predictors.

Science.gov (United States)

Rose, Susan; Dhandayudham, Arun

2014-06-01

Compulsive and addictive forms of consumption and buying behaviour have been researched in both business and medical literature. Shopping enabled via the Internet now introduces new features to the shopping experience that translate to positive benefits for the shopper. Evidence now suggests that this new shopping experience may lead to problematic online shopping behaviour. This paper provides a theoretical review of the literature relevant to online shopping addiction (OSA). Based on this selective review, a conceptual model of OSA is presented. The selective review of the literature draws on searches within databases relevant to both clinical and consumer behaviour literature including EBSCO, ABI Pro-Quest, Web of Science - Social Citations Index, Medline, PsycINFO and Pubmed. The article reviews current thinking on problematic, and specifically addictive, behaviour in relation to online shopping. The review of the literature enables the extension of existing knowledge into the Internet-context. A conceptual model of OSA is developed with theoretical support provided for the inclusion of 7 predictor variables: low self-esteem, low self-regulation; negative emotional state; enjoyment; female gender; social anonymity and cognitive overload. The construct of OSA is defined and six component criteria of OSA are proposed based on established technological addiction criteria. Current Internet-based shopping experiences may trigger problematic behaviours which can be classified on a spectrum which at the extreme end incorporates OSA. The development of a conceptual model provides a basis for the future measurement and testing of proposed predictor variables and the outcome variable OSA.

Health promotion in obstructive sleep apnea syndrome.

Science.gov (United States)

Corrêa, Camila de Castro; Blasca, Wanderléia Quinhoneiro; Berretin-Felix, Giédre

2015-04-01

Introduction Obstructive sleep apnea syndrome (OSAS), which is commonly underdiagnosed, has a high occurrence in the world population. Health education concerning sleep disorders and OSAS should be implemented. Objectives The objective was to identify studies related to preventive actions on sleep disorders, with emphasis on OSAS. Data Synthesis A literature review was conducted using Lilacs, Medline, PubMed, and Scopus by combining the following keywords: "Health Promotion," "Sleep Disorders," "Primary Prevention," "Health Education," and "Obstructive Sleep Apnea Syndromes." Initially, 1,055 papers, from 1968 to 2013, were located, with the majority from the Scopus database. The inclusion criteria were applied, and four articles published between 2006 and 2012 were included in the present study. Conclusions The studies on preventive actions in sleep disorders, with emphasis on OSAS, involved the general population and professionals and students in the health field and led to increased knowledge on sleep disorders and more appropriate practices.

When to Suspect Sleep Apnea and What to Do About It.

Science.gov (United States)

Kimoff, R John

2015-07-01

Obstructive sleep apnea (OSA), which is characterized by recurrent upper airway obstruction during sleep with resultant hypoxia-reoxygenation and sleep fragmentation, is prevalent among patients with cardiovascular disease. Refractory hypertension, nocturnal angina or arrhythmias, and stroke in particular should prompt consideration of OSA. The symptoms of OSA include snoring and excessive daytime sleepiness; risk factors include obesity and reduced upper airway dimensions. Up to 50% of patients with congestive heart failure (CHF) may manifest OSA, central sleep apnea-Cheyne-Stokes respiration (CSA-CSR), or both. Patients with CSA-CSR may present with fatigue, disrupted sleep, and paroxysmal nocturnal dyspnea. Objective sleep recording is required to document the nature and severity of sleep apnea. The gold standard is in-laboratory overnight polysomnography (PSG), including monitoring of electroencephalography and other signals to determine sleep-wake state, and recording of body position, airflow, respiratory effort, and pulse oximetry. Portable cardiorespiratory recorders are now approved for diagnosis in patients without comorbidities. Full PSG is recommended for diagnosis in all other cases, although OSA and CSA-CSR can be identified from portable recorders in some patients with CHF and other conditions. The objectives of treatment are to improve symptoms, quality of life, and cardiovascular outcomes. The mainstay of treatment for moderate-to-severe OSA is positive airway pressure (PAP). Automated PAP devices may be used in uncomplicated OSA, whereas continuous fixed PAP is the treatment of choice for other patients with OSA, and may also treat a proportion of patients with CSA-CSR. A form of bi-level PAP known as adaptive servoventilation is effective in treating a majority of patients with CSA-CSR. Copyright © 2015 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.

Altered Regional Brain Cortical Thickness in Pediatric Obstructive Sleep Apnea

Directory of Open Access Journals (Sweden)

Paul M. Macey

2018-01-01

Full Text Available RationaleObstructive sleep apnea (OSA affects 2–5% of all children and is associated with cognitive and behavioral deficits, resulting in poor school performance. These psychological deficits may arise from brain injury, as seen in preliminary findings of lower gray matter volume among pediatric OSA patients. However, the psychological deficits in OSA are closely related to functions in the cortex, and such brain areas have not been specifically assessed. The objective was to determine whether cortical thickness, a marker of possible brain injury, is altered in children with OSA.MethodsWe examined regional brain cortical thicknesses using high-resolution T1-weighted magnetic resonance images in 16 pediatric OSA patients (8 males; mean age ± SD = 8.4 ± 1.2 years; mean apnea/hypopnea index ± SD = 11 ± 6 events/h and 138 controls (8.3 ± 1.1 years; 62 male; 138 subjects from the NIH Pediatric MRI database to identify cortical thickness differences in pediatric OSA subjects.ResultsCortical thinning occurred in multiple regions including the superior frontal, ventral medial prefrontal, and superior parietal cortices. The left side showed greater thinning in the superior frontal cortex. Cortical thickening was observed in bilateral precentral gyrus, mid-to-posterior insular cortices, and left central gyrus, as well as right anterior insula cortex.ConclusionChanges in cortical thickness are present in children with OSA and likely indicate disruption to neural developmental processes, including maturational patterns of cortical volume increases and synaptic pruning. Regions with thicker cortices may reflect inflammation or astrocyte activation. Both the thinning and thickening associated with OSA in children may contribute to the cognitive and behavioral dysfunction frequently found in the condition.

Evaluation studies on the combined effect of hydrothermal treatment and octenyl succinylation on the physic-chemical, structural and digestibility characteristics of sweet potato starch.

Science.gov (United States)

Lv, Qing-Qing; Li, Gao-Yang; Xie, Qiu-Tao; Zhang, Bao; Li, Xiao-Min; Pan, Yi; Chen, Han-Qing

2018-08-01

In order to increase the degree of substitution (DS), a combination of heat-moisture treatment (HMT) and octenyl succinylation (OSA) was used to modify sweet potato starch (SPS). The content of OSA had significant influence on the DS of starch, and DS of HMT OSA-modified SPS (HOSA-SPS) was higher than that of OSA-modified SPS (OSA-SPS), indicating that prior HMT could enhance the reaction. HOSA-SPS showed higher contents of SDS and RS in comparison with OSA-SPS as OSA concentration was beyond 6%. HMT decreased swelling power of starch while OSA modification had a contrary role (p < 0.05). Scanning electron microscopy (SEM) showed starch was destroyed by OSA modification while HMT had slight effect on the structure. X-ray diffraction (XRD) indicated that crystal type of starch was transformed from C- to A-type resulted from HMT, and remained unchanged by OSA modification. The onset, peak, and conclusion gelatinization temperatures of starch increased by HMT and decreased by OSA modification (p < 0.05). Copyright © 2018 Elsevier Ltd. All rights reserved.

Optical Illusions: A Presentation for High School Mathematics Students.

Science.gov (United States)

Brandes, Louis Grant

1983-01-01

Optical illusions are assumed to be of interest to high school mathematics students. The article indicates how a topic can be both educational and entertaining. Readers are invited to try to construct some illusions on their own, and to see if they can classify them. (MP)

Maximal exercise capacity in patients with obstructive sleep apnoea syndrome: A systematic review and meta-analysis.

Science.gov (United States)

Mendelson, Monique; Marillier, Mathieu; Bailly, Sébastien; Flore, Patrice; Borel, Jean-Christian; Vivodtzev, Isabelle; Doutreleau, Stéphane; Tamisier, Renaud; Pépin, Jean-Louis; Verges, Samuel

2018-04-26

Maximal aerobic capacity is a strong health predictor and peak oxygen consumption (VO 2peak ) is considered a reflection of total body health. No systematic reviews or meta-analysis' to date have synthesised the existing data regarding VO 2peak in patients with obstructive sleep apnoea (OSA).A systematic review of English and French articles using Pubmed/Medline and Embase included studies assessing VO 2peak of OSA patients in mL·kg -1 ·min -1 compared with controls or in % predicted. Two independent reviewers analysed the studies, extracted the data and assessed the quality of evidence.Mean VO 2peak expressed in mL·kg -1 ·min -1 was significantly lower in patients with OSA when compared with controls (mean difference=-2.7 mL·kg -1 ·min -1 ; p<0.001; n=850). This reduction in VO 2peak was found to be larger in non-obese patients (BMI<30 kg·m -2 ). Mean VO 2peak in % predicted was 90.7±21.0% in OSA patients (n=643).OSA patients present reduced maximal aerobic capacity, which can be associated with increased cardiovascular risks and reduced survival in certain patient subgroups. Maximal exercise testing can be useful to characterise functional limitation and to evaluate health status in OSA patients. Registration # CRD42017057319. Copyright ©ERS 2018.

The effect of sleep apnea severity on cardiac autonomic activity during night time in obstructive sleep apnea patients

Directory of Open Access Journals (Sweden)

Gulay Ozkececi

Full Text Available ABSTRACT CONTEXT AND OBJECTIVE: Impaired autonomic cardiac function is an important consequence of obstructive sleep apnea (OSA. This impairment is mainly due to intermittent hypoxia episodes following apneas. However, the impact of apnea severity on autonomic cardiac function remains unclear. The aim of this study was to evaluate the relationship between the severity of sleep apnea and heart rate turbulence (HRT and heart rate variability (HRV in OSA. DESIGN AND SETTING: Observational cross-sectional study conducted in the Departments of Cardiology and Pulmonary Diseases, Afyon Kocatepe University, Turkey. METHODS: 106 patients with OSA and 27 healthy volunteers were enrolled. Based on apnea hypopnea index (AHI values, obstructive sleep apnea severity was classified as follows: mild OSA (AHI ≥ 5 and 30. HRV and HRT parameters were assessed via 24-hour digital Holter electrocardiogram recordings for all subjects. RESULTS: HRV and HRT results were significantly lower among OSA patients than among control subjects (P < 0.05. However, there were no significant differences in HRT and HRV between the three patient subgroups. Correlations did emerge between AHI and the NN-interval parameter RMSSD and between oxygen desaturation and turbulence slope (respectively: r = -0.22, P = 0.037; and r = -0.28, P = 0.025. CONCLUSION: HRT and HRV results deteriorate in OSA. Correlations between apnea severity and these parameters seem to be present.

Clinical utility of the Chinese version of the Pediatric Daytime Sleepiness Scale in children with obstructive sleep apnea syndrome and narcolepsy.

Science.gov (United States)

Yang, Chien-Ming; Huang, Yu-Shu; Song, Yu-Chen

2010-04-01

The present study examined the psychometric properties of the Chinese version of the Pediatric Daytime Sleepiness Scale (PDSS) and the utility of the PDSS as a screening tool for pathological daytime sleepiness in teenagers with obstructive sleep apnea (OSA) and narcolepsy. The PDSS was first administered to 238 middle and high school students to assess the reliability of the scale, and then administered to 28 teenagers with OSA, 31 teenagers with narcolepsy, and 34 normal controls to evaluate its clinical utility. Test-retest reliability and internal consistency were acceptable. The PDSS scores were significantly higher in narcoleptic subjects than in subjects with OSA, and higher in OSA syndrome (OSAS) subjects than normal controls. Furthermore, the scores decreased in narcoleptic subjects after medical treatment. Both reliability and validity were proven to be good. As a screening tool for narcolepsy, receiver operator characteristic (ROC) curve analysis showed that the PDSS, with a cut-off score of 16/17, had good sensitivity (87.1%) and fair specificity (74.3%) for identifying individuals with narcolepsy. When used for screening OSA, however, the differentiating power was not as good. The PDSS is a reliable and valid tool for the measurement of sleepiness in clinical youth populations. When used as a screening tool, it is useful for sleep disorders involving more severe pathological sleepiness, as in narcolepsy.

Effects of Chronic Obstructive Pulmonary Disease and Obstructive Sleep Apnea on Cognitive Functions: Evidence for a Common Nature

Directory of Open Access Journals (Sweden)

Georgia Andreou

2014-01-01

Full Text Available Patients with chronic obstructive pulmonary disease (COPD and obstructive sleep apnea syndrome (OSAS show similar neurocognitive impairments. Effects are more apparent in severe cases, whereas in moderate and mild cases the effects are equivocal. The exact mechanism that causes cognitive dysfunctions in both diseases is still unknown and only suggestions have been made for each disease separately. The primary objective of this review is to present COPD and OSAS impact on cognitive functions. Secondly, it aims to examine the potential mechanisms by which COPD and OSAS can be linked and provide evidence for a common nature that affects cognitive functions in both diseases. Patients with COPD and OSAS compared to normal distribution show significant deficits in the cognitive abilities of attention, psychomotor speed, memory and learning, visuospatial and constructional abilities, executive skills, and language. The severity of these deficits in OSAS seems to correlate with the physiological events such as sleep defragmentation, apnea/hypopnea index, and hypoxemia, whereas cognitive impairments in COPD are associated with hypoventilation, hypoxemia, and hypercapnia. These factors as well as vascocerebral diseases and changes in systemic hemodynamic seem to act in an intermingling and synergistic way on the cause of cognitive dysfunctions in both diseases. However, low blood oxygen pressure seems to be the dominant factor that contributes to the presence of cognitive deficits in both COPD and OSAS.

Rhythm disturbances in childhood obstructive sleep apnea during apnea-hypopnea episodes

International Nuclear Information System (INIS)

Khositseth, Anant; Chokechuleekorn, Jittamas; Kuptanon, Teeradej; Leejakpai, Anchalee

2013-01-01

Obstructive sleep apnoea (OSA) can result in cardiovascular complications. Nocturnal arrhythmias are reported up to 50% of adult OSA patients. Arrhythmias and heart rate variability in children with OSA have not been well studied. We sought to study rhythm disturbances in childhood OSA and also to analyze the relationship of heart rate variability to the severity of OSA in children. In a retrospective cross sectional study, records of children aged < 15 years with history of snoring and suspected OSA, who had undergone polysomnography (PSG) for first time were analyzed. The cardiac rhythm and heart rate variability were studied during PSG. A total of 124 patients diagnosed with OSA were grouped into mild (n = 52), moderate (n = 30), and severe (n = 42) OSA. During PSG, all had sinus arrhythmias and only three patients had premature atrial contractions (PACs). The standard deviation of heart rate (SD-HR) during rapid eye movement (REM) sleep in severe OSA (9.1 ± 2.4) was significantly higher than SD-HR in mild OSA (7.5 ± 1.3, P < 0.0001). The maximum heart rate (max-HR) during REM-sleep in severe OSA (132.1 ± 22.1) was significantly higher than the max-HR in mild OSA (121.3 ± 12.6 bpm, P = 0.016). There was no significant arrhythmia in children with OSA during their sleep. Heart rate variability correlated with the severity of OSA

Obstructive sleep apnea screening by integrating snore feature classes

International Nuclear Information System (INIS)

Abeyratne, U R; De Silva, S; Hukins, C; Duce, B

2013-01-01

Obstructive sleep apnea (OSA) is a serious sleep disorder with high community prevalence. More than 80% of OSA suffers remain undiagnosed. Polysomnography (PSG) is the current reference standard used for OSA diagnosis. It is expensive, inconvenient and demands the extensive involvement of a sleep technologist. At present, a low cost, unattended, convenient OSA screening technique is an urgent requirement. Snoring is always almost associated with OSA and is one of the earliest nocturnal symptoms. With the onset of sleep, the upper airway undergoes both functional and structural changes, leading to spatially and temporally distributed sites conducive to snore sound (SS) generation. The goal of this paper is to investigate the possibility of developing a snore based multi-feature class OSA screening tool by integrating snore features that capture functional, structural, and spatio-temporal dependences of SS. In this paper, we focused our attention to the features in voiced parts of a snore, where quasi-repetitive packets of energy are visible. Individual snore feature classes were then optimized using logistic regression for optimum OSA diagnostic performance. Consequently, all feature classes were integrated and optimized to obtain optimum OSA classification sensitivity and specificity. We also augmented snore features with neck circumference, which is a one-time measurement readily available at no extra cost. The performance of the proposed method was evaluated using snore recordings from 86 subjects (51 males and 35 females). Data from each subject consisted of 6–8 h long sound recordings, made concurrently with routine PSG in a clinical sleep laboratory. Clinical diagnosis supported by standard PSG was used as the reference diagnosis to compare our results against. Our proposed techniques resulted in a sensitivity of 93±9% with specificity 93±9% for females and sensitivity of 92±6% with specificity 93±7% for males at an AHI decision threshold of 15 events

Effects of Adenotonsillectomy on Neurocognitive Function in Pediatric Obstructive Sleep Apnea Syndrome

Directory of Open Access Journals (Sweden)

Fumie Horiuchi

2014-01-01

Full Text Available Obstructive sleep apnea syndrome (OSAS in children does not only present with symptoms of sleep disturbances but also with associated symptoms such as growth failure, enuresis, academic learning difficulties, and behavioral problems, including attention deficit/hyperactivity disorder- (ADHD- like symptoms. We evaluated neurocognitive functions before and after adenotonsillectomy in a patient with OSAS. An 11-year-old boy suspected of having ADHD with nocturnal enuresis was referred for evaluation. He was found to have adenotonsillar hypertrophy. Presence of snoring was evident only after detailed medical interview. Polysomnography confirmed the diagnosis of OSAS, which was subsequently treated by adenotonsillectomy. The apnea/hypopnea index decreased from 21.9 at baseline to 1.8 after surgery, and the frequency of enuresis fell from almost nightly to 2-3 times per month. Neurocognitive and behavioral assessment after the treatment of OSAS showed significant improvement in cognitive functions, especially attention capacity and considerable amelioration of behavioral problems including ADHD-like symptoms. As the most common cause of pediatric OSAS is adenotonsillar hypertrophy, medical interview and oropharyngeal examination should always be performed in children suspected of having ADHD. The necessity of sleep evaluation for children with ADHD-like symptoms was also emphasized.

TST, as a polysomnographic variable, is superior to the apnea hypopnea index for evaluating intermittent hypoxia in severe obstructive sleep apnea.

Science.gov (United States)

Zhang, Xiao-Bin; Zen, Hui-Qing; Lin, Qi-Chang; Chen, Gong-Ping; Chen, Li-Da; Chen, Hua

2014-10-01

The polysomnography (PSG) index of the apnea hypopnea index (AHI) is considered the 'gold standard' for stratifying the severity of obstructive sleep apnea (OSA). However, AHI cannot reflect the true characteristic of chronic intermittent hypoxia (CIH), which may trigger systemic inflammation in some OSA patients. High-sensitivity C-reactive protein (hsCRP) is considered a biomarker of systemic inflammation in OSA patients. The aim of the present study was to evaluate the relationship between PSG variables and hsCRP in men with severe OSA. Men with severe OSA (AHI ≥ 30 events/h) diagnosed by PSG were enrolled. AHI and body mass index were matched between a high hsCRP group (hsCRP ≥ 3.0 mg/L) and a low hsCRP group. A blood sample was taken for serum hsCRP analysis. Multiple regression analysis was performed to assess independent predictors of high hsCRP. One hundred and fifty-two subjects were enrolled in the study (76 in each group). Mean serum hsCRP was 3.76 ± 2.13 mg/L. The mean percentage of total sleep time spent with SaO2 hypoxia variables.

Drug-Induced Sleep Endoscopy Changes the Treatment Concept in Patients with Obstructive Sleep Apnoea

Directory of Open Access Journals (Sweden)

Jaroslava Hybášková

2016-01-01

Full Text Available The present study evaluated whether drug-induced sleep endoscopy (DISE helps identify the site of obstruction in patients with obstructive sleep apnoea (OSA. A total of 51 consecutive patients with polysomnography-confirmed OSA were enrolled in this prospective study. The presumed site of obstruction was determined according to history, otorhinolaryngologic examination, and polysomnography and a therapeutic plan designed before DISE. In 11 patients with severe OSA and/or previously failed continuous positive airway pressure (CPAP treatment, DISE with simultaneous CPAP was performed. Multilevel collapse was noted in 49 patients (96.1%. The most frequent multilevel collapse was palatal, oropharyngeal, and tongue base collapse (n=17, 33.3%, followed by palatal and oropharyngeal collapse (n=12, 23.5%. Pathology of the larynx (epiglottis was observed in 16 patients (31.4%. The laryngeal obstruction as a reason for intolerance of CPAP was observed in 3/11 (27.3% patients. After DISE, the surgical plan was changed in 31 patients (60.8%. The results indicate that DISE helps identify the site of obstruction in the upper airways in patients with OSA more accurately and that the larynx plays an important role in OSA.

Obstructive sleep apnea and cortical thickness in females and males.

Science.gov (United States)

Macey, Paul M; Haris, Natasha; Kumar, Rajesh; Thomas, M Albert; Woo, Mary A; Harper, Ronald M

2018-01-01

Obstructive sleep apnea (OSA) affects approximately 10% of adults, and alters brain gray and white matter. Psychological and physiological symptoms of the disorder are sex-specific, perhaps related to greater injury occurs in female than male patients in white matter. Our objective was to identify influences of OSA separated by sex on cortical gray matter. We assessed cortical thickness in 48 mild-severe OSA patients (mean age±std[range] = 46.5±9.0[30.8-62.7] years; apnea-hypopnea index = 32.6±21.1[6-102] events/hour; 12 female, 36 male; OSA severity: 5 mild, 18 moderate, 25 severe) and 62 controls (mean age = 47.7±8.9[30.9-65.8] years; 22 female, 40 male). All OSA patients were recently-diagnosed via polysomnography, and control subjects screened and a subset assessed with sleep studies. We used high-resolution magnetic resonance imaging to identify OSA-related cortical thinning, based on a model with condition and sex as independent variables. OSA and OSA-by-sex interaction effects were assessed (Pfrontal lobe in female OSA vs. all other groups. Significant thinning within the pre- and post-central gyri and the superior temporal gyrus, extending into the insula, appeared between the general OSA populations vs. control subjects. No areas showed increased thickness in OSA vs. controls or positive female OSA interaction effects. Reduced cortical thickness likely represents tissue atrophy from long term injury, including death of neurons and supporting glia from repeated intermittent hypoxic exposure in OSA, although disease comordities may also contribute to thinning. Lack of polysomnography in all control subjects means results may be confounded by undiagnosed OSA. The greater cortical injury in cognitive areas of female OSA patients may underlie enhanced symptoms in that group. The thinning associated with OSA in male and females OSA patients may contribute to autonomic dysregulation and impaired upper airway sensori-motor function.

Responsive, Flexible and Scalable Broader Impacts (Invited)

Science.gov (United States)

Decharon, A.; Companion, C.; Steinman, M.

2010-12-01

In many educator professional development workshops, scientists present content in a slideshow-type format and field questions afterwards. Drawbacks of this approach include: inability to begin the lecture with content that is responsive to audience needs; lack of flexible access to specific material within the linear presentation; and “Q&A” sessions are not easily scalable to broader audiences. Often this type of traditional interaction provides little direct benefit to the scientists. The Centers for Ocean Sciences Education Excellence - Ocean Systems (COSEE-OS) applies the technique of concept mapping with demonstrated effectiveness in helping scientists and educators “get on the same page” (deCharon et al., 2009). A key aspect is scientist professional development geared towards improving face-to-face and online communication with non-scientists. COSEE-OS promotes scientist-educator collaboration, tests the application of scientist-educator maps in new contexts through webinars, and is piloting the expansion of maps as long-lived resources for the broader community. Collaboration - COSEE-OS has developed and tested a workshop model bringing scientists and educators together in a peer-oriented process, often clarifying common misconceptions. Scientist-educator teams develop online concept maps that are hyperlinked to “assets” (i.e., images, videos, news) and are responsive to the needs of non-scientist audiences. In workshop evaluations, 91% of educators said that the process of concept mapping helped them think through science topics and 89% said that concept mapping helped build a bridge of communication with scientists (n=53). Application - After developing a concept map, with COSEE-OS staff assistance, scientists are invited to give webinar presentations that include live “Q&A” sessions. The webinars extend the reach of scientist-created concept maps to new contexts, both geographically and topically (e.g., oil spill), with a relatively small

WILD PINEAPPLE (ANANAS BRACTEATUS (LINDL., VAR. ALBUS HARVESTED IN FOREST PATCHES IN RURAL AREA OF VIÇOSA, MINAS GERIAS, BRAZIL: EXCELLENT SOURCE OF MINERALS AND GOOD SOURCE OF PROTEINS AND VITAMIN C

Directory of Open Access Journals (Sweden)

GALDINO XAVIER DE PAULA FILHO

2016-01-01

Full Text Available ABSTRACT In the rural region of the municipality of Viçosa, Minas Gerais, forest patches are encountered and they present a great diversity of wild and edible fruit, where wild pineapple (Ananas bracteatus (Lindl., var. albus is one of those of greatest occurrence. Given that, little is known about the nutritional characteristics of this fruit, the present study aimed to investigate the physical and physic-chemical characteristics, chemical composition (titratable acidity, total soluble solids, pH, moisture content, ash, protein, lipids and dietary fiber, carotenoids (a-carotene, ß-carotene, ß-cryptoxanthin and lycopene, vitamin C (AA and DHA by HPLC-DAD, vitamin E (a-, ß-, ?-, d-, tocopherols and tocotrienols by HPLC-fluorescence, and minerals (P, K, Ca, Mg, Cu, Fe, Zn, Mn, Na, Cr, Se and Mo by ICP-AES. Fruits showed a moisture content average of 78.5 g 100g-1, 16.3 ° Brix of soluble solids, titratable acidity equal to 1.71 g 100g-1 of citric acid, 1.66 g 100g-1 of dietary fiber, 1.41 g 100 g-1 of lipids and caloric density of 83.15 kcal 100g-1. We considered it a source of carbohydrates (12.82 g 100g-1, proteins (4.79 g 100g-1 and Zn (0.98 mg 100g-1; a good source of vitamin C (18.70 mg 100g-1; and an excellent source of Cu (0.48 mg 100g-1, Fe (2.05 mg 100g-1, Mn (8.87 mg 100g-1 and Mo (0.15 mg 100g-1.

Treatment outcomes of obstructive sleep apnoea in obese community-dwelling children: the NANOS study.

Science.gov (United States)

Alonso-Álvarez, María Luz; Terán-Santos, Joaquin; Navazo-Egüia, Ana Isabel; Martinez, Mónica Gonzalez; Jurado-Luque, María José; Corral-Peñafiel, Jaime; Duran-Cantolla, Joaquin; Cordero-Guevara, José Aurelio; Kheirandish-Gozal, Leila; Gozal, David

2015-09-01

The first line of treatment of obstructive sleep apnoea syndrome (OSAS) in children consists of adenotonsillectomy (T&A). The aim of the present study was to evaluate treatment outcomes of OSAS among obese children recruited from the community.A cross-sectional, prospective, multicentre study of Spanish obese children aged 3-14 years, with four groups available for follow-up: group 1: non-OSAS with no treatment; group 2: dietary treatment; group 3: surgical treatment; and group 4: continuous positive airway pressure treatment.117 obese children (60 boys, 57 girls) with a mean age of 11.3±2.9 years completed the initial (T0) and follow-up (T1) assessments. Their mean body mass index (BMI) at T1 was 27.6±4.7 kg·m(-2), corresponding to a BMI Z-score of 1.34±0.59. Mean respiratory disturbance index (RDI) at follow-up was 3.3±3.9 events·h(-1). Among group 1 children, 21.2% had an RDI ≥3 events·h(-1) at T1, the latter being present in 50% of group 2, and 43.5% in group 3. In the binary logistic regression model, age emerged as a significant risk factor for residual OSAS (odds ratio 1.49, 95% confidence interval 1.01-2.23; p<0.05) in obese children surgically treated, and RDI at T0 as well as an increase in BMI emerged as significant risk factors for persistent OSAS in obese children with dietary treatment (OR 1.82, 95% CI 1.09-3.02 (p<0.03) and OR 8.71, 95% CI 1.24-61.17 (p=0.03)).Age, RDI at diagnosis and obesity are risk factors for relatively unfavourable OSAS treatment outcomes at follow-up. Copyright ©ERS 2015.

ENS RRFM '98. Transactions. Oral presentations and posters

International Nuclear Information System (INIS)

1998-01-01

The four sessions at the second international topical meeting on research reactor fuel management dealt with the following topics: Challenges and requirements for research reactors; Fissile materials supply, fuel fabrication and licensing; Reactor operation and fuel safety; Back-end options and transportation. In this volume the text of the invited and contributed papers as well as of the posters is included

ENS RRFM '98. Transactions. Oral presentations and posters

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-07-01

The four sessions at the second international topical meeting on research reactor fuel management dealt with the following topics: Challenges and requirements for research reactors; Fissile materials supply, fuel fabrication and licensing; Reactor operation and fuel safety; Back-end options and transportation. In this volume the text of the invited and contributed papers as well as of the posters is included.

Health Promotion in Obstructive Sleep Apnea Syndrome

Directory of Open Access Journals (Sweden)

Corrêa, Camila de Castro

2015-01-01

Full Text Available Introduction Obstructive sleep apnea syndrome (OSAS, which is commonly underdiagnosed, has a high occurrence in the world population. Health education concerning sleep disorders and OSAS should be implemented. Objectives The objective was to identify studies related to preventive actions on sleep disorders, with emphasis on OSAS. Data Synthesis A literature review was conducted using Lilacs, Medline, PubMed, and Scopus by combining the following keywords: “Health Promotion,” “Sleep Disorders,” “Primary Prevention,” “Health Education,” and “Obstructive Sleep Apnea Syndromes.” Initially, 1,055 papers, from 1968 to 2013, were located, with the majority from the Scopus database. The inclusion criteria were applied, and four articles published between 2006 and 2012 were included in the present study. Conclusions The studies on preventive actions in sleep disorders, with emphasis on OSAS, involved the general population and professionals and students in the health field and led to increased knowledge on sleep disorders and more appropriate practices.

Upper airway sensory function in children with obstructive sleep apnea syndrome.

Science.gov (United States)

Tapia, Ignacio E; Bandla, Preetam; Traylor, Joel; Karamessinis, Laurie; Huang, Jingtao; Marcus, Carole L

2010-07-01

Children with the obstructive sleep apnea syndrome (OSAS) have impaired responses to hypercapnia, subatmospheric pressure, and inspiratory resistive loading during sleep. This may be due, in part, to an impairment in the afferent limb of the upper airway sensory pathway. Therefore, we hypothesized that children with OSAS had diminished upper airway sensation compared to controls. Case-control. Academic hospital. Subjects with OSAS aged 6-16 years, and age- and BMI-matched controls. Two-point discrimination (TPD) was measured during wakefulness with modified calipers in the anterior tongue, right interior cheek, and hard palate. Thirteen children with OSAS and 9 controls were tested. The age (mean +/- SD) for OSAS and controls was 11 +/- 4 vs. 13 +/- 2 years (NS); OSAS BMI Z score 2.4 +/- 0.5, controls 2.2 +/- 0.5 (NS); OSAS apnea hypopnea index 31 +/- 48, controls 0.4 +/- 0.5 events/hour (P Children with OSAS had impaired TPD in the anterior tongue (median [range]) = 9 [3-14] mm, controls 3 [1-7], P = 0.002) and hard palate (OSAS 6 [3-9] mm, controls 3 [1-4], P children with OSAS during wakefulness. We speculate that this impairment might be due to a primary sensory function abnormality or secondary to nerve damage and/or hypoxemia caused by OSAS. Further studies after treatment of OSAS are needed.

Radiological findings in patients with obstructive sleep apnea

Energy Technology Data Exchange (ETDEWEB)

Mello Junior, Carlos Fernando de; Guimaraes Filho, Helio Antonio; Gomes, Camila Albuquerque de Brito; Paiva, Camila Caroline de Amorim, E-mail: carlosfmello@hotmail.com [Universidade Federal da Paraiba UFPB, Joao Pessoa (Brazil)

2013-01-15

Obstructive sleep apnea (OSA) is characterized by recurrent upper airway obstruction occurring at the level of the pharynx during sleep. Although cephalometric analysis is an important method in the diagnosis of craniofacial deformities, CT and magnetic resonance imaging have been highlighted as the major imaging methods to investigate the possible causes of OSA, which, in most cases, is multifactorial. Magnetic resonance and CT both allow an excellent evaluation of the various anatomical planes of the site of obstruction, which enables better clinical assessment and surgical approach. This pictorial essay aims to describe the aspects that must be evaluated in the diagnostic imaging of patients presenting with the major predisposing factors for OSA. (author)

Radiological findings in patients with obstructive sleep apnea

International Nuclear Information System (INIS)

Mello Junior, Carlos Fernando de; Guimaraes Filho, Helio Antonio; Gomes, Camila Albuquerque de Brito; Paiva, Camila Caroline de Amorim

2013-01-01

Obstructive sleep apnea (OSA) is characterized by recurrent upper airway obstruction occurring at the level of the pharynx during sleep. Although cephalometric analysis is an important method in the diagnosis of craniofacial deformities, CT and magnetic resonance imaging have been highlighted as the major imaging methods to investigate the possible causes of OSA, which, in most cases, is multifactorial. Magnetic resonance and CT both allow an excellent evaluation of the various anatomical planes of the site of obstruction, which enables better clinical assessment and surgical approach. This pictorial essay aims to describe the aspects that must be evaluated in the diagnostic imaging of patients presenting with the major predisposing factors for OSA. (author)

Asthma and Obstructive Sleep Apnea

Directory of Open Access Journals (Sweden)

Yi-Xian Qiao

2015-01-01

Full Text Available Objective: To get a comprehensive understanding about the relationship between obstructive sleep apnea (OSA and asthma by reviewing the epidemiology, pathophysiology, and clinical manifestation and then summarizing the latest progress on diagnosis and treatment. Data Sources: Articles referred in this review were mainly collected from a comprehensive search of the PubMed published in English from 1990 to 2015 with the terms "OSA" and "asthma" as the main keywords. Highly regarded older publications were also included. Study Selection: Information about the features of the two diseases in common, the pathophysiologic association between them and their current treatments from the literature search were identified, retrieved, and summarized. Results: Both OSA and asthma are very prevalent conditions. The incidences of them have kept on rising in recent years. Asthma is often accompanied by snoring and apnea, and OSA often combines with asthma, as well. They have many predisposing and aggravating factors in common. Possible shared direct mechanistic links between them include mechanical effects, intermittent hypoxia, nerve reflex, inflammation, leptin, etc. Indirect mechanistic links include medication, nose diseases, smoking, obesity, and gastroesophageal reflux disease. Since OSA presents many similar features with nocturnal asthma, some scholars termed them as a sole syndrome - "alternative overlap syndrome," and proved that asthma symptoms in those patients could be improved through the treatment of continuous positive airway pressure. Conclusions: OSA and asthma are closely associated in pathogenesis, symptoms, and therapies. With the growing awareness of the relationship between them, we should raise our vigilance on the coexistence of OSA in those difficult-to-control asthmatic patients. Further studies are still needed to guide the clinical works.

Dysphagia and Obstructive Sleep Apnea in Acute, First-Ever, Ischemic Stroke.

Science.gov (United States)

Losurdo, Anna; Brunetti, Valerio; Broccolini, Aldobrando; Caliandro, Pietro; Frisullo, Giovanni; Morosetti, Roberta; Pilato, Fabio; Profice, Paolo; Giannantoni, Nadia Mariagrazia; Sacchetti, Maria Luisa; Testani, Elisa; Vollono, Catello; Della Marca, Giacomo

2018-03-01

Obstructive sleep apnea (OSA) and dysphagia are common in acute stroke and are both associated with increased risk of complications and worse prognosis. The aims of the present study were (1) to evaluate the prevalence of OSA and dysphagia in patients with acute, first-ever, ischemic stroke; (2) to investigate their clinical correlates; and (3) to verify if these conditions are associated in acute ischemic stroke. We enrolled a cohort of 140 consecutive patients with acute-onset (<48 hours), first-ever ischemic stroke. Computed tomography (CT) and magnetic resonance imaging scans confirmed the diagnosis. Neurological deficit was measured using the National Institutes of Health Stroke Scale (NIHSS) by examiners trained and certified in the use of this scale. Patients underwent a clinical evaluation of dysphagia (Gugging Swallowing Screen) and a cardiorespiratory sleep study to evaluate the presence of OSA. There are 72 patients (51.4%) with obstructive sleep apnea (OSA+), and there are 81 patients (57.8%) with dysphagia (Dys+). OSA+ patients were significantly older (P = .046) and had greater body mass index (BMI) (P = .002), neck circumference (P = .001), presence of diabetes (P = .013), and hypertension (P < .001). Dys+ patients had greater NIHSS (P < .001), lower Alberta Stroke Programme Early CT Score (P < .001), with greater BMI (P = .030). The association of OSA and dysphagia was greater than that expected based on the prevalence of each condition in acute stroke (P < .001). OSA and dysphagia are associated in first-ever, acute ischemic stroke. Copyright © 2018 National Stroke Association. Published by Elsevier Inc. All rights reserved.

Frequency of distribution of leptin receptor gene polymorphism in obstructive sleep apnea patients.

Science.gov (United States)

Popko, K; Gorska, E; Wasik, M; Stoklosa, A; Pływaczewski, R; Winiarska, M; Gorecka, D; Sliwinski, P; Demkow, U

2007-11-01

Leptin is an adipocyte-derived hormone regulating energy homeostasis and body weight. Leptin concentration is increased in patients with the obstructive sleep apnea syndrome (OSAS). Leptin receptor (LEPR) is a single transmembrane protein belonging to the superfamily of cytokine receptors related by a structure to the hemopoietin receptor family. The aim of the present study was to evaluate the frequency of distribution of leptin receptor gene polymorphism GLN223ARG in OSAS patients compared with healthy controls. The examined group included 179 subjects: 102 OSAS patients (74 men and 28 women) and 77 non-apneic controls (39 men and 38 women). Genomic DNA was isolated with the use of a column method and genotyping of DNA sequence variation was carried out by restriction enzyme analysis of PCR-amplified DNA. The results revealed a significant correlation between the polymorphism of LEPR and OSAS. Carriers of Arg allele in homozygotic genotype Arg/Arg and heterozygotic genotype Gln/Arg were more often obese and developed OSAS than the group of carriers of homozygotic Gln/Gln genotype. This tendency was observed in the whole examined population and in the group of obese women. We also found the highest levels of total cholesterol, LDL, HDL, and triglycerides in the group of homozygotic Arg/Arg genotype carriers, lower in heterozygotic Gln/Arg genotype carriers, and the lowest in the group of persons carring homozygotic Gln/Gln genotype. The presence of Arg allel seems linked to a higher risk of obesity and higher lipid levels in OSAS patients. OSAS may have a strong genetic basis due to the effects from a variety of genes including those for leptin receptor.

3rd International School and Conference “Saint Petersburg OPEN 2016” on Optoelectronics, Photonics, Engineering and Nanostructures

International Nuclear Information System (INIS)

2016-01-01

Dear Colleagues, 3rd International School and Conference “Saint Petersburg OPEN 2016” on Optoelectronics, Photonics, Engineering and Nanostructures was held on March 28 - 30, 2016 at St. Petersburg Academic University of the Russian Academy of Sciences. The School and Conference included a series of invited talks given by leading professors with the aim of introducing young scientists to the actual problems and major advances in modern physics and technology. The keynote speakers were Mircea Guina (Tampere University of Technology, Finland) Evgeny I. Terukov (Ioffe Institute RAS, Russia) Victor M. Ustinov (Ioffe Institute RAS, Russia) Peter G. Kazansky (University of Southampton, UK) Alexander O. Golubok (ITMO University, Russia) Georgy E. Cirlin (St Petersburg Academic University RAS, Russia) Levon V. Asryan (Virginia Polytechnic Institute and State University, USA) Andrey A. Lipovskii (Peter the Great St.Petersburg Polytechnic University, Russia) During the poster session all undergraduate and graduate students attending the conference presented their works. A large number of participants with more than 280 student attendees from all over the world allowed the Conference to provide a fertile ground for the fruitful discussions between the young scientists as well as to become a perfect platform for the valuable discussions between student authors and highly experienced scientists. The best student papers, which were selected by the Program Committee and by the invited speakers based on the theses and their poster presentation, were awarded with diplomas of the conference - see the photos. This year “Saint Petersburg OPEN 2016” is organized by St. Petersburg Academic University in cooperation with Peter the Great St. Petersburg Polytechnic University. The School and Conference is supported by the Russian Foundation for Basic Research (Project N 16-32-10060) , Russian Science Foundation, SPIE (The International Society for Optics and Photonics) and OSA (The

Association of Canine Osteosarcoma and Monocyte Phenotype and Chemotactic Function.

Science.gov (United States)

Tuohy, J L; Lascelles, B D X; Griffith, E H; Fogle, J E

2016-07-01

Monocytes/macrophages are likely key cells in immune modulation in dogs with osteosarcoma (OSA). Increased peripheral monocyte counts are negatively correlated with shorter disease-free intervals in dogs with OSA. Understanding the monocyte/macrophage's modulatory role in dogs with OSA can direct further studies in immunotherapy development for OSA. That OSA evades the immune response by down-regulating monocyte chemokine receptor expression and migratory function, and suppresses host immune responses. Eighteen dogs with OSA that have not received definitive treatment and 14 healthy age-matched controls Clinical study-expression of peripheral blood monocyte cell surface receptors, monocyte mRNA expression and cytokine secretion, monocyte chemotaxis, and survival were compared between clinical dogs with OSA and healthy control dogs. Cell surface expression of multiple chemokine receptors is significantly down-regulated in peripheral blood monocytes of dogs with OSA. The percentage expression of CCR2 (median 58%, range 2-94%) and CXCR2 expression (median 54%, range 2-92%) was higher in control dogs compared to dogs with OSA (CCR2 median 29%, range 3-45%, P = 0.0006; CXCR2 median 23%, range 0.2-52%, P = 0.0007). Prostaglandin E2 (PGE2 ) (OSA, median 347.36 pg/mL, range 103.4-1268.5; control, 136.23 pg/mL, range 69.93-542.6, P = .04) and tumor necrosis factor-alpha (TNF-α) (P = .02) levels are increased in OSA monocyte culture supernatants compared to controls. Peripheral blood monocytes of dogs with OSA exhibit decreased chemotactic function when compared to control dogs (OSA, median 1.2 directed to random migration, range 0.8-1.25; control, 1.6, range of 0.9-1.8, P = .018). Dogs with OSA have decreased monocyte chemokine receptor expression and monocyte chemotaxis, potential mechanisms by which OSA might evade the immune response. Reversal of monocyte dysfunction using immunotherapy could improve survival in dogs with OSA. Copyright © 2016 The Authors. Journal of

Obstructive Sleep Apnea and Retinopathy in Patients with Type 2 Diabetes. A Longitudinal Study

Science.gov (United States)

Altaf, Quratul A.; Dodson, Paul; Ali, Asad; Raymond, Neil T.; Wharton, Helen; Fellows, Hannah; Hampshire-Bancroft, Rachel; Shah, Mirriam; Shepherd, Emma; Miah, Jamili; Barnett, Anthony H.

2017-01-01

Rationale: Obstructive sleep apnea (OSA) is associated with several pathophysiological deficits found in diabetic retinopathy (DR). Hence, it’s plausible that OSA could play a role in the pathogenesis of sight-threatening DR (STDR). Objectives: To assess the relationship between OSA and DR in patients with type 2 diabetes and to assess whether OSA is associated with its progression. Methods: A longitudinal study was conducted in diabetes clinics within two U.K. hospitals. Patients known to have any respiratory disorder (including OSA) were excluded. DR was assessed using two-field 45-degree retinal images for each eye. OSA was assessed using a home-based multichannel cardiorespiratory device. Measurements and Main Results: A total of 230 patients were included. STDR and OSA prevalence rates were 36.1% and 63.9%, respectively. STDR prevalence was higher in patients with OSA than in those without OSA (42.9% vs. 24.1%; P = 0.004). After adjustment for confounders, OSA remained independently associated with STDR (odds ratio, 2.3; 95% confidence interval, 1.1–4.9; P = 0.04). After a median (interquartile range) follow-up of 43.0 (37.0–51.0) months, patients with OSA were more likely than patients without OSA to develop preproliferative/proliferative DR (18.4% vs. 6.1%; P = 0.02). After adjustment for confounders, OSA remained an independent predictor of progression to preproliferative/proliferative DR (odds ratio, 5.2; 95% CI confidence interval, 1.2–23.0; P = 0.03). Patients who received continuous positive airway pressure treatment were significantly less likely to develop preproliferative/proliferative DR. Conclusions: OSA is associated with STDR in patients with type 2 diabetes. OSA is an independent predictor for the progression to preproliferative/proliferative DR. Continuous positive airway pressure treatment was associated with reduction in preproliferative/proliferative DR. Interventional studies are needed to assess the impact of OSA

Full-text publication of abstracts presented at meetings of a Latin American scientific society.

Science.gov (United States)

Dicembrino, Manuela; Anderson, Mariana; Vely, Ana Gabriela; Ossorio, María Fabiana; Ferrero, Fernando

2014-12-01

To estimate the proportion of abstracts presented at meetings of the Latin American Society for Pediatric Research that are fully-published, to describe the reasons for not publishing papers, and to assess the impact of funding on the publication rate. Abstracts presented at meetings held between 2005 and 2009 were included. Authors were contacted and invited to take a survey on the publication of their work or the reasons not to do it. Information was collected on 232 (71.4%) of the 325 abstracts presented. Of these, 58.6% were fully-published (136/232). Funded studies (40.0%) had more chances of publication (OR: 2.2; 95% CI: 1.2-3.9). "Lack of time" was the most common reason for failure to publish (35/96). 58.6% of abstracts presented at meetings of the Latin American Society for Pediatric Research, were published as full-text articles; lack of time was the most common reason for failure to publish. Funded research had more chances of being published.

Effect of Continuous Positive Airway Pressure on Adiponectin in Patients with Obstructive Sleep Apnea: A Meta-Analysis.

Directory of Open Access Journals (Sweden)

Li-Da Chen

Full Text Available Obstructive sleep apnea (OSA has been suggested to be associated with low levels of adiponectin. Continuous positive airway pressure (CPAP is the gold standard treatment for OSA; however, previous studies assessing the effect of CPAP on adiponectin in patients with OSA yielded conflicting results. The present meta-analysis was performed to determine whether CPAP therapy could increase adiponectin levels.Two reviewers independently searched PubMed, Cochrane library, Embase and Web of Science before February 2015. Information on characteristics of subjects, study design and pre- and post-CPAP treatment of serum adiponectin was extracted for analysis. Standardized mean difference (SMD was used to analyze the summary estimates for CPAP therapy.Eleven studies involving 240 patients were included in this meta-analysis, including ten observational studies and one randomized controlled study. The meta-analysis showed that there was no change of adiponectin levels before and after CPAP treatment in OSA patients (SMD = 0.059, 95% confidence interval (CI = -0.250 to 0.368, z = 0.37, p = 0.710. Subgroup analyses indicated that the results were not affected by age, baseline body mass index, severity of OSA, CPAP therapy duration, sample size and racial differences.This meta-analysis suggested that CPAP therapy has no impact on adiponectin in OSA patients, without significant changes in body weight. Further large-scale, well-designed long-term interventional investigations are needed to clarify this issue.