The finite element response Matrix method

International Nuclear Information System (INIS)

Nakata, H.; Martin, W.R.

1983-01-01

A new method for global reactor core calculations is described. This method is based on a unique formulation of the response matrix method, implemented with a higher order finite element method. The unique aspects of this approach are twofold. First, there are two levels to the overall calculational scheme: the local or assembly level and the global or core level. Second, the response matrix scheme, which is formulated at both levels, consists of two separate response matrices rather than one response matrix as is generally the case. These separate response matrices are seen to be quite beneficial for the criticality eigenvalue calculation, because they are independent of k /SUB eff/. The response matrices are generated from a Galerkin finite element solution to the weak form of the diffusion equation, subject to an arbitrary incoming current and an arbitrary distributed source. Calculational results are reported for two test problems, the two-dimensional International Atomic Energy Agency benchmark problem and a two-dimensional pressurized water reactor test problem (Biblis reactor), and they compare well with standard coarse mesh methods with respect to accuracy and efficiency. Moreover, the accuracy (and capability) is comparable to fine mesh for a fraction of the computational cost. Extension of the method to treat heterogeneous assemblies and spatial depletion effects is discussed

Matrix isolation FT-IR spectroscopy and molecular orbital study of sarcosine methyl ester

OpenAIRE

Gómez-Zavaglia, Andrea; Fausto, R.

2004-01-01

N-methylglycine methyl ester (sarcosine-Me) has been studied by matrix isolation FT-IR spectroscopy and molecular orbital calculations undertaken at the DFT/B3LYP and MP2 levels of theory with the 6-311++G(d,p) and 6-31++G(d,p) basis set, respectively. Twelve different conformers were located in the potential energy surface of the studied compound, with the ASC conformer being the ground conformational state. This form is analogous to the dimethylglycine methyl ester most stable conformer and...

Influence of electron correlation and degeneracy on the Fukui matrix and extension of frontier molecular orbital theory to correlated quantum chemical methods.

Science.gov (United States)

Bultinck, Patrick; Van Neck, Dimitri; Acke, Guillaume; Ayers, Paul W

2012-02-21

The Fukui function is considered as the diagonal element of the Fukui matrix in position space, where the Fukui matrix is the derivative of the one particle density matrix (1DM) with respect to the number of electrons. Diagonalization of the Fukui matrix, expressed in an orthogonal orbital basis, explains why regions in space with negative Fukui functions exist. Using a test set of molecules, electron correlation is found to have a remarkable effect on the eigenvalues of the Fukui matrix. The Fukui matrices at the independent electron model level are mathematically proven to always have an eigenvalue equal to exactly unity while the rest of the eigenvalues possibly differ from zero but sum to zero. The loss of idempotency of the 1DM at correlated levels of theory causes the loss of these properties. The influence of electron correlation is examined in detail and the frontier molecular orbital concept is extended to correlated levels of theory by defining it as the eigenvector of the Fukui matrix with the largest eigenvalue. The effect of degeneracy on the Fukui matrix is examined in detail, revealing that this is another way by which the unity eigenvalue and perfect pairing of eigenvalues can disappear.

Orbital functionals in density-matrix- and current-density-functional theory

Energy Technology Data Exchange (ETDEWEB)

Helbig, N

2006-05-15

Density-Functional Theory (DFT), although widely used and very successful in the calculation of several observables, fails to correctly describe strongly correlated materials. In the first part of this work we, therefore, introduce reduced-densitymatrix- functional theory (RDMFT) which is one possible way to treat electron correlation beyond DFT. Within this theory the one-body reduced density matrix (1- RDM) is used as the basic variable. Our main interest is the calculation of the fundamental gap which proves very problematic within DFT. In order to calculate the fundamental gap we generalize RDMFT to fractional particle numbers M by describing the system as an ensemble of an N and an N+1 particle system (with N{<=}M{<=}N+1). For each fixed particle number, M, the total energy is minimized with respect to the natural orbitals and their occupation numbers. This leads to the total energy as a function of M. The derivative of this function with respect to the particle number has a discontinuity at integer particle number which is identical to the gap. In addition, we investigate the necessary and sufficient conditions for the 1- RDM of a system with fractional particle number to be N-representable. Numerical results are presented for alkali atoms, small molecules, and periodic systems. Another problem within DFT is the description of non-relativistic many-electron systems in the presence of magnetic fields. It requires the paramagnetic current density and the spin magnetization to be used as basic variables besides the electron density. However, electron-gas-based functionals of current-spin-density-functional Theory (CSDFT) exhibit derivative discontinuities as a function of the magnetic field whenever a new Landau level is occupied, which makes them difficult to use in practice. Since the appearance of Landau levels is, intrinsically, an orbital effect it is appealing to use orbital-dependent functionals. We have developed a CSDFT version of the optimized

Convergence Improvement of Response Matrix Method with Large Discontinuity Factors

International Nuclear Information System (INIS)

Yamamoto, Akio

2003-01-01

In the response matrix method, a numerical divergence problem has been reported when extremely small or large discontinuity factors are utilized in the calculations. In this paper, an alternative response matrix formulation to solve the divergence problem is discussed, and properties of iteration matrixes are investigated through eigenvalue analyses. In the conventional response matrix formulation, partial currents between adjacent nodes are assumed to be discontinuous, and outgoing partial currents are converted into incoming partial currents by the discontinuity factor matrix. Namely, the partial currents of the homogeneous system (i.e., homogeneous partial currents) are treated in the conventional response matrix formulation. In this approach, the spectral radius of an iteration matrix for the partial currents may exceed unity when an extremely small or large discontinuity factor is used. Contrary to this, an alternative response matrix formulation using heterogeneous partial currents is discussed in this paper. In the latter approach, partial currents are assumed to be continuous between adjacent nodes, and discontinuity factors are directly considered in the coefficients of a response matrix. From the eigenvalue analysis of the iteration matrix for the one-group, one-dimensional problem, the spectral radius for the heterogeneous partial current formulation does not exceed unity even if an extremely small or large discontinuity factor is used in the calculation; numerical stability of the alternative formulation is superior to the conventional one. The numerical stability of the heterogeneous partial current formulation is also confirmed by the two-dimensional light water reactor core analysis. Since the heterogeneous partial current formulation does not require any approximation, the converged solution exactly reproduces the reference solution when the discontinuity factors are directly derived from the reference calculation

Efficient sparse matrix-matrix multiplication for computing periodic responses by shooting method on Intel Xeon Phi

Science.gov (United States)

Stoykov, S.; Atanassov, E.; Margenov, S.

2016-10-01

Many of the scientific applications involve sparse or dense matrix operations, such as solving linear systems, matrix-matrix products, eigensolvers, etc. In what concerns structural nonlinear dynamics, the computations of periodic responses and the determination of stability of the solution are of primary interest. Shooting method iswidely used for obtaining periodic responses of nonlinear systems. The method involves simultaneously operations with sparse and dense matrices. One of the computationally expensive operations in the method is multiplication of sparse by dense matrices. In the current work, a new algorithm for sparse matrix by dense matrix products is presented. The algorithm takes into account the structure of the sparse matrix, which is obtained by space discretization of the nonlinear Mindlin's plate equation of motion by the finite element method. The algorithm is developed to use the vector engine of Intel Xeon Phi coprocessors. It is compared with the standard sparse matrix by dense matrix algorithm and the one developed by Intel MKL and it is shown that by considering the properties of the sparse matrix better algorithms can be developed.

Construction of the Fock Matrix on a Grid-Based Molecular Orbital Basis Using GPGPUs.

Science.gov (United States)

Losilla, Sergio A; Watson, Mark A; Aspuru-Guzik, Alán; Sundholm, Dage

2015-05-12

We present a GPGPU implementation of the construction of the Fock matrix in the molecular orbital basis using the fully numerical, grid-based bubbles representation. For a test set of molecules containing up to 90 electrons, the total Hartree-Fock energies obtained from reference GTO-based calculations are reproduced within 10(-4) Eh to 10(-8) Eh for most of the molecules studied. Despite the very large number of arithmetic operations involved, the high performance obtained made the calculations possible on a single Nvidia Tesla K40 GPGPU card.

Introduction to Computational Chemistry: Teaching Hu¨ckel Molecular Orbital Theory Using an Excel Workbook for Matrix Diagonalization

Science.gov (United States)

Litofsky, Joshua; Viswanathan, Rama

2015-01-01

Matrix diagonalization, the key technique at the heart of modern computational chemistry for the numerical solution of the Schrödinger equation, can be easily introduced in the physical chemistry curriculum in a pedagogical context using simple Hückel molecular orbital theory for p bonding in molecules. We present details and results of…

Nonorthogonal orbital based N-body reduced density matrices and their applications to valence bond theory. I. Hamiltonian matrix elements between internally contracted excited valence bond wave functions

Science.gov (United States)

Chen, Zhenhua; Chen, Xun; Wu, Wei

2013-04-01

In this series, the n-body reduced density matrix (n-RDM) approach for nonorthogonal orbitals and their applications to ab initio valence bond (VB) methods are presented. As the first paper of this series, Hamiltonian matrix elements between internally contracted VB wave functions are explicitly provided by means of nonorthogonal orbital based RDM approach. To this end, a more generalized Wick's theorem, called enhanced Wick's theorem, is presented both in arithmetical and in graphical forms, by which the deduction of expressions for the matrix elements between internally contracted VB wave functions is dramatically simplified, and the matrix elements are finally expressed in terms of tensor contractions of electronic integrals and n-RDMs of the reference VB self-consistent field wave function. A string-based algorithm is developed for the purpose of evaluating n-RDMs in an efficient way. Using the techniques presented in this paper, one is able to develop new methods and efficient algorithms for nonorthogonal orbital based many-electron theory much easier than by use of the first quantized formulism.

Response Matrix Method Development Program at Savannah River Laboratory

International Nuclear Information System (INIS)

Sicilian, J.M.

1976-01-01

The Response Matrix Method Development Program at Savannah River Laboratory (SRL) has concentrated on the development of an effective system of computer codes for the analysis of Savannah River Plant (SRP) reactors. The most significant contribution of this program to date has been the verification of the accuracy of diffusion theory codes as used for routine analysis of SRP reactor operation. This paper documents the two steps carried out in achieving this verification: confirmation of the accuracy of the response matrix technique through comparison with experiment and Monte Carlo calculations; and establishment of agreement between diffusion theory and response matrix codes in situations which realistically approximate actual operating conditions

Hartree--Fock density matrix equation

International Nuclear Information System (INIS)

Cohen, L.; Frishberg, C.

1976-01-01

An equation for the Hartree--Fock density matrix is discussed and the possibility of solving this equation directly for the density matrix instead of solving the Hartree--Fock equation for orbitals is considered. Toward that end the density matrix is expanded in a finite basis to obtain the matrix representative equation. The closed shell case is considered. Two numerical schemes are developed and applied to a number of examples. One example is given where the standard orbital method does not converge while the method presented here does

Response matrix properties and convergence implications for an interface-current nodal formulation

International Nuclear Information System (INIS)

Yang, W.S.

1995-01-01

An analytic study was performed of the properties and the associated convergence implications of the response matrix equations derived via the widely used nodal expansion method. By using the DIF3D nodal formulation in hexagonal-z geometry as a concrete example, an analytic expression for the response matrix is first derived by using the hexagonal prism symmetry transformations. The spectral radius of the local response matrix is shown to be always 2 -norm of the response matrix is shown to be ∞ -norm is not always 2 - and l ∞ -norms of the response matrix are found to increase as the removal cross section decreases. On the other hand, for a given removal cross section, each of these matrix norms takes its minimum at a certain diffusion coefficient and increases as the diffusion coefficient deviates from this value. Based on these matrix norms, sufficient conditions for the convergence of the iteration schemes for solving the response matrix equations are discussed. The range of node-height-to-hexagon-pitch ratios that guarantees a positive solution is derived as a function of the diffusion coefficient and the removal cross section

Empirically Determined Response Matrices for On-Line Orbit and Energy Correction at Jefferson Lab

International Nuclear Information System (INIS)

Leigh Harwood; Alicia Hofler; Michele Joyce; Valeri Lebedev; David Bryan

2001-01-01

Jefferson Lab uses feedback loops (less than 1 hertz update rate) to correct drifts in CEBAF's electron beam orbit and energy. Previous incarnations of these loops used response matrices that were computed by a numerical model of the machine. Jefferson Lab is transitioning this feedback system to use empirically determined response matrices whereby the software introduces small orbit or energy deviations using the loop's actuators and measures the system response with the loop's sensors. This method is in routine use for orbit correction. This paper will describe the orbit correction system and future plans to extend this method to energy correction

Fundamentals of the orbit and response for TianQin

Science.gov (United States)

Hu, Xin-Chun; Li, Xiao-Hong; Wang, Yan; Feng, Wen-Fan; Zhou, Ming-Yue; Hu, Yi-Ming; Hu, Shou-Cun; Mei, Jian-Wei; Shao, Cheng-Gang

2018-05-01

TianQin is a space-based laser interferometric gravitational wave detector aimed at detecting gravitational waves at low frequencies (0.1 mHz–1 Hz). It is formed by three identical drag-free spacecrafts in an equilateral triangular constellation orbiting around the Earth. The distance between each pair of spacecrafts is approximately 1.7 × 105 ~km . The spacecrafts are interconnected by infrared laser beams forming up to three Michelson-type interferometers. The detailed mission design and the study of science objectives for the TianQin project depend crucially on the orbit and the response of the detector. In this paper, we provide the analytic expressions for the coordinates of the orbit for each spacecraft in the heliocentric-ecliptic coordinate system to the leading orders. This enables a sufficiently accurate study of science objectives and data analysis, and serves as a first step to further orbit design and optimization. We calculate the response of a single Michelson detector to plane gravitational waves in arbitrary waveform which is valid in the full range of the sensitive frequencies. It is then used to generate the more realistic sensitivity curve of TianQin. We apply this model on a reference white-dwarf binary as a proof of principle.

Natural excitation orbitals from linear response theories : Time-dependent density functional theory, time-dependent Hartree-Fock, and time-dependent natural orbital functional theory

NARCIS (Netherlands)

Van Meer, R.; Gritsenko, O. V.; Baerends, E. J.

2017-01-01

Straightforward interpretation of excitations is possible if they can be described as simple single orbital-to-orbital (or double, etc.) transitions. In linear response time-dependent density functional theory (LR-TDDFT), the (ground state) Kohn-Sham orbitals prove to be such an orbital basis. In

Electron paramagnetic resonance g-tensors from state interaction spin-orbit coupling density matrix renormalization group

Science.gov (United States)

Sayfutyarova, Elvira R.; Chan, Garnet Kin-Lic

2018-05-01

We present a state interaction spin-orbit coupling method to calculate electron paramagnetic resonance g-tensors from density matrix renormalization group wavefunctions. We apply the technique to compute g-tensors for the TiF3 and CuCl42 - complexes, a [2Fe-2S] model of the active center of ferredoxins, and a Mn4CaO5 model of the S2 state of the oxygen evolving complex. These calculations raise the prospects of determining g-tensors in multireference calculations with a large number of open shells.

Free radicals in an adamantane matrix. XIII. Electron paramagnetic resonance study of sigma* - π* orbital crossover in fluorinated pyridine anions

International Nuclear Information System (INIS)

Yim, M.B.; DiGregorio, S.; Wood, D.E.

1977-01-01

Pentafluoropyridine,2,3,4,6-tetrafluoropyridine, 2,6-difluoropyridine, and 2-fluoropyridine anion radicals were produced by x irradiation of an adamantane matrix which was doubly doped with the aromatic precursors and Me 3 NBH 3 and their EPR spectra obtained. The large fluorine hyperfine splitting constants (hfsc) of penta- and 2,3,4,6-tetrafluoropyridine anions and the small fluorine hfsc's of 2,6-di- and 2-fluoropyridine anions suggest that the former two are sigma radicals while the latter two are π radicals. The sigma*-π* orbital crossover phenomenon observed in these fluorinated pyridine anions is explained in terms of the combined effects of stabilization of sigma* orbitals and destabilization of π* orbitals. The EPR results show that nitrogen has a negligible contribution to the unpaired electron sigma* orbitals. INDO calculations were performed for the various states and the results compared with experiment

Neutron response matrix for unfolding NE-213 measurements to 21 MeV

International Nuclear Information System (INIS)

Ingersoll, D.T.; Wehring, B.W.; Johnson, R.H.

1976-01-01

A neutron response matrix from measured neutron responses of NE-213 in the energy range of 0.2 to 22 MeV is presented. An interpolation scheme was used to construct an 81-column matrix from the data of Verbinski, Burrus, Love, Zobel, and Hill. As a test of the new response matrix, the Cf-252 neutron spectrum was measured and unfolded using the new response matrix and the FORIST unfolding code. The spectrum agrees well with previous measurements at lower energies, while providing new information above 8 MeV

Analytic robust stability analysis of SVD orbit feedback

CERN Document Server

Pfingstner, Jürgen

2012-01-01

Orbit feedback controllers are indispensable for the operation of modern particle accelerators. Many such controllers are based on the decoupling of the inputs and outputs of the system to be controlled with the help of the singular value decomposition (SVD controller). It is crucial to verify the stability of SVD controllers, also in the presence of mismatches between the used accelerator model and the real machine (robust stability problem). In this paper, analytical criteria for guaranteed stability margins of SVD orbit feedback systems for three different types of model mismatches are presented: scaling errors of actuators and BPMs (beam position monitors) and additive errors of the orbit response matrix. For the derivation of these criteria, techniques from robust control theory have been used, e.g the small gain theorem. The obtained criteria can be easily applied directly to other SVD orbit feedback systems. As an example, the criteria were applied to the orbit feedback system of the Compact Linear ...

Preconditioned Krylov and Gauss-Seidel solutions of response matrix equations

International Nuclear Information System (INIS)

Lewis, E.E.; Smith, M.A.; Yang, W.S.; Wollaber, A.

2011-01-01

The use of preconditioned Krylov methods is examined as an alternative to the partitioned matrix acceleration applied to red-black Gauss Seidel (RBGS) iteration that is presently used in the variational nodal code, VARIANT. We employ the GMRES algorithm to treat non-symmetric response matrix equations. A pre conditioner is formulated for the within-group diffusion equation which is equivalent to partitioned matrix acceleration of RBGS iterations. We employ the pre conditioner, which closely parallels two-level p multigrid, to improve RBGS and GMRES algorithms. Of the accelerated algorithms, GMRES converges with less computational effort than RBGS and therefore is chosen for further development. The p multigrid pre conditioner requires response matrices with two or more degrees of freedom (DOF) per interface that are polynomials, which are both orthogonal and hierarchical. It is therefore not directly applicable to very fine mesh calculations that are both slow to converge and that are often modeled with response matrices with only one DOF per interface. Orthogonal matrix aggregation (OMA) is introduced to circumvent this difficulty by combining N×N fine mesh response matrices with one DOF per interface into a coarse mesh response matrix with N orthogonal DOF per interface. Numerical results show that OMA used alone or in combination with p multigrid preconditioning substantially accelerates GMRES solutions. (author)

Preconditioned Krylov and Gauss-Seidel solutions of response matrix equations

Energy Technology Data Exchange (ETDEWEB)

Lewis, E.E., E-mail: e-lewis@northwestern.edu [Department of Mechanical Engineering, Northwestern University, Evanston, IL (United States); Smith, M.A.; Yang, W.S.; Wollaber, A., E-mail: masmith@anl.gov, E-mail: wsyang@anl.gov, E-mail: wollaber@lanl.gov [Nuclear Engineering Division, Argonne National Laboratory, Argonne, IL (United States)

2011-07-01

The use of preconditioned Krylov methods is examined as an alternative to the partitioned matrix acceleration applied to red-black Gauss Seidel (RBGS) iteration that is presently used in the variational nodal code, VARIANT. We employ the GMRES algorithm to treat non-symmetric response matrix equations. A pre conditioner is formulated for the within-group diffusion equation which is equivalent to partitioned matrix acceleration of RBGS iterations. We employ the pre conditioner, which closely parallels two-level p multigrid, to improve RBGS and GMRES algorithms. Of the accelerated algorithms, GMRES converges with less computational effort than RBGS and therefore is chosen for further development. The p multigrid pre conditioner requires response matrices with two or more degrees of freedom (DOF) per interface that are polynomials, which are both orthogonal and hierarchical. It is therefore not directly applicable to very fine mesh calculations that are both slow to converge and that are often modeled with response matrices with only one DOF per interface. Orthogonal matrix aggregation (OMA) is introduced to circumvent this difficulty by combining N×N fine mesh response matrices with one DOF per interface into a coarse mesh response matrix with N orthogonal DOF per interface. Numerical results show that OMA used alone or in combination with p multigrid preconditioning substantially accelerates GMRES solutions. (author)

Conformational study of sarcosine as probed by matrix-isolation FT-IR spectroscopy and molecular orbital calculations

OpenAIRE

Gómez-Zavaglia, Andrea; Fausto, R.

2003-01-01

Sarcosine (N-methylglycine) has been studied by matrix-isolation FT-IR spectroscopy and molecular orbital calculations undertaken at the DFT/B3LYP and MP2 levels of theory with the 6-311++G(d, p) and 6-31++G(d, p) basis set, respectively. Eleven different conformers were located in the potential energy surface (PES) of sarcosine, with the ASC conformer being the ground conformational state. This form is analogous to the glycine most stable conformer and is characterized by a NH...O= intramole...

Spin-orbit scattering in superconducting nanoparticles

Energy Technology Data Exchange (ETDEWEB)

Alhassid, Y. [Center for Theoretical Physics, Sloane Physics Laboratory, Yale University, New Haven, Connecticut, 06520 (United States); Nesterov, K.N. [Department of Physics, University of Wisconsin-Madison, Madison, Wisconsin, 53706 (United States)

2017-06-15

We review interaction effects in chaotic metallic nanoparticles. Their single-particle Hamiltonian is described by the proper random-matrix ensemble while the dominant interaction terms are invariants under a change of the single-particle basis. In the absence of spin-orbit scattering, the nontrivial invariants consist of a pairing interaction, which leads to superconductivity in the bulk, and a ferromagnetic exchange interaction. Spin-orbit scattering breaks spin-rotation invariance and when it is sufficiently strong, the only dominant nontrivial interaction is the pairing interaction. We discuss how the magnetic response of discrete energy levels of the nanoparticle (which can be measured in single-electron tunneling spectroscopy experiments) is affected by such pairing correlations and how it can provide a signature of pairing correlations. We also consider the spin susceptibility of the nanoparticle and discuss how spin-orbit scattering changes the signatures of pairing correlations in this observable. (copyright 2016 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

Hexagonal response matrix using symmetries

International Nuclear Information System (INIS)

Gotoh, Y.

1991-01-01

A response matrix for use in core calculations for nuclear reactors with hexagonal fuel assemblies is presented. It is based on the incoming currents averaged over the half-surface of a hexagonal node by applying symmetry theory. The boundary conditions of the incoming currents on the half-surface of the node are expressed by a complete set of orthogonal vectors which are constructed from symmetrized functions. The expansion coefficients of the functions are determined by the boundary conditions of incoming currents. (author)

The Jost function and the S-matrix asymptotic expressions for large complex angular momenta in the presence of central and spin-orbital interaction

International Nuclear Information System (INIS)

Pivovarchik, V.N.; Poplavskij, I.V.

1982-01-01

The asymptotic behaviour of the regular solution, the Yost function and the S-matrix of the Schrodinger equation is estimated by means of WKB quasiclassical method at a fixed physical value of energy (k>0) for lambda→infinity in the domain Re lambda→0 for central and spin-orbital interaction [ru

A nodal method based on matrix-response method

International Nuclear Information System (INIS)

Rocamora Junior, F.D.; Menezes, A.

1982-01-01

A nodal method based in the matrix-response method, is presented, and its application to spatial gradient problems, such as those that exist in fast reactors, near the core - blanket interface, is investigated. (E.G.) [pt

Response matrix of a multisphere neutron spectrometer with an 3 He proportional counter

International Nuclear Information System (INIS)

Vega C, H.R.; Manzanares A, E.; Hernandez D, V.M.; Mercado S, G.A.

2005-01-01

The response matrix of a Bonner sphere spectrometer was calculated by use of the MCNP code. As thermal neutron counter, the spectrometer has a 3.2 cm-diameter 3 He-filled proportional counter which is located at the center of a set of polyethylene spheres. The response was calculated for 0, 3, 5, 6, 8, 10, 12, and 16 inches-diameter polyethylene spheres for neutrons whose energy goes from 10 -9 to 20 MeV. The response matrix was compared with a set of responses measured with several monoenergetic neutron sources. In this comparison the calculated matrix agrees with the experimental results. The matrix was also compared with the response matrix calculated for the PTB C spectrometer. Even though that calculation was carried out using a detailed model to describe the proportional counter; both matrices do agree, but small differences are observed in the bare case because of the difference in the model used during calculations. Other differences are in some spheres for 14.8 and 20 MeV neutrons, probably due to the differences in the cross sections used during both calculations. (Author) 28 refs., 1 tab., 6 figs

Charge-spin-orbital dynamics of one-dimensional two-orbital Hubbard model

Energy Technology Data Exchange (ETDEWEB)

Onishi, Hiroaki [Advanced Science Research Center, Japan Atomic Energy Agency, Tokai, Ibaraki 319-1195 (Japan)

2010-01-15

We study the real-time evolution of a charge-excited state in a one-dimensional e{sub g}-orbital degenerate Hubbard model, by a time-dependent density-matrix renormalization group method. Considering a chain along the z direction, electrons hop between adjacent 3z{sup 2}-r{sup 2} orbitals, while x{sup 2}-y{sup 2} orbitals are localized. For the charge-excited state, a holon-doublon pair is introduced into the ground state at quarter filling. At initial time, there is no electron in a holon site, while a pair of electrons occupies 3z{sup 2}-r{sup 2} orbital in a doublon site. As the time evolves, the holon motion is governed by the nearest-neighbor hopping, but the electron pair can transfer between 3z{sup 2}-r{sup 2} orbital and x{sup 2}-y{sup 2} orbital through the pair hopping in addition to the nearest-neighbor hopping. Thus holon and doublon propagate at different speed due to the pair hopping that is characteristic of multi-orbital systems.

Nodal coupling by response matrix principles

International Nuclear Information System (INIS)

Ancona, A.; Becker, M.; Beg, M.D.; Harris, D.R.; Menezes, A.D.; VerPlanck, D.M.; Pilat, E.

1977-01-01

The response matrix approach has been used in viewing a reactor node in isolation and in characterizing the node by reflection and trans-emission factors. These are then used to generate invariant imbedding parameters, which in turn are used in a nodal reactor simulator code to compute core power distributions in two and three dimensions. Various nodal techniques are analyzed and converted into a single invariant imbedding formalism

Effect of an elliptical orbit on SPECT resolution and image uniformity

International Nuclear Information System (INIS)

Gottschalk, S.; Salem, D.

1982-01-01

This paper studies the impact of elliptical motion on SPECT resolution and detector flood correction as implemented in a Technicare Omega 500. Bringing the detector closer to the object improves detector resolution in each view, which results in improved resolution in the reconstructed image. In the Omega 500 the elliptical orbit is realized by a succession of translational and rotational motions of the detector head. This introduces motion of the detector center relative to the object center. Statistical fluctuations in the flood correction matrix due to the finite acquisition time result in ring artifacts for the circular orbit. The relative center motion of an elliptical orbit results in an averaging of the flood correction noise and a significant reduction in artifacts. These two aspects of SPECT spatial resolution and flood correction response improvement in elliptical orbit have been analyzed through computer simulations for point sources and a uniform activity 20 x 30 cm ellipse. Results compared a 35 cm diameter circular orbit to a 35 x 25 cm elliptical orbit

Exact and approximate exchange potentials investigated in terms of their matrix elements with the Kohn-Sham orbitals

International Nuclear Information System (INIS)

Holas, A.; Cinal, M.

2005-01-01

Three approximate exchange potentials of high accuracy v x Y (r), Y=A,B,C, for the density-functional theory applications are obtained by replacing the matrix elements of the exact potential between the Kohn-Sham (KS) orbitals with such elements of the Fock exchange operator (within the virtual-occupied subset only) in three representations found for any local potential. A common identity is the base of these representations. The potential v x C happens to be the same as that derived by Harbola and Sahni, and v x A as that derived by Gritsenko and Baerends, and Della Sala and Goerling. The potentials obtained can be expressed in terms of occupied KS orbitals only. At large r, their asymptotic form -1/r is the same as that of the exact potential. The high quality of these three approximations is demonstrated by direct comparison with the exact potential and using various consistency tests. A common root established for the three approximations could be helpful in finding new and better approximations via modification of identities employed in the present investigation

Analysis of the half-projected Hartree--Fock function: density matrix, natural orbitals, and configuration interaction equivalence

International Nuclear Information System (INIS)

Smeyers, Y.G.; Delgado-Barrio, G.

1976-01-01

The half-projected Hartree--Fock function for singlet states (HPHF) is analyzed in terms of natural electronic configurations. For this purpose the HPHF spinless density matrix and its natural orbitals are first deduced. It is found that the HPHF function does not contain any contribution from odd-times excited configurations. It is seen in addition, in the case of the singlet ground states, this function is approximately equivalent to two closed-shell configurations, although the nature of the excited one depends on the nuclear geometry. An example is given in the case of the LiH ground state. Finally, the application of this model for studying systems of more than two atoms is criticized

Closed orbit feedback with digital signal processing

International Nuclear Information System (INIS)

Chung, Y.; Kirchman, J.; Lenkszus, F.

1994-01-01

The closed orbit feedback experiment conducted on the SPEAR using the singular value decomposition (SVD) technique and digital signal processing (DSP) is presented. The beam response matrix, defined as beam motion at beam position monitor (BPM) locations per unit kick by corrector magnets, was measured and then analyzed using SVD. Ten BPMs, sixteen correctors, and the eight largest SVD eigenvalues were used for closed orbit correction. The maximum sampling frequency for the closed loop feedback was measured at 37 Hz. Using the proportional and integral (PI) control algorithm with the gains Kp = 3 and K I = 0.05 and the open-loop bandwidth corresponding to 1% of the sampling frequency, a correction bandwidth (-3 dB) of approximately 0.8 Hz was achieved. Time domain measurements showed that the response time of the closed loop feedback system for 1/e decay was approximately 0.25 second. This result implies ∼ 100 Hz correction bandwidth for the planned beam position feedback system for the Advanced Photon Source storage ring with the projected 4-kHz sampling frequency

Nonlinear response matrix methods for radiative transfer

International Nuclear Information System (INIS)

Miller, W.F. Jr.; Lewis, E.E.

1987-01-01

A nonlinear response matrix formalism is presented for the solution of time-dependent radiative transfer problems. The essential feature of the method is that within each computational cell the temperature is calculated in response to the incoming photons from all frequency groups. Thus the updating of the temperature distribution is placed within the iterative solution of the spaceangle transport problem, instead of being placed outside of it. The method is formulated for both grey and multifrequency problems and applied in slab geometry. The method is compared to the more conventional source iteration technique. 7 refs., 1 fig., 4 tabs

Matrix of response functions for xenon gamma-ray detector

International Nuclear Information System (INIS)

Shustov, A.E.; Vlasik, K.F.; Grachev, V.M.; Dmitrenko, V.V.; Novikov, A.S.; P'ya, S.N.; Ulin, S.E.; Uteshev, Z.M.; Chernysheva, I.V.

2014-01-01

An approach of creation of response matrix using simulation GEANT4 gamma-ray Monte-Carlo method has been described for gamma-ray spectrometer based on high pressure xenon impulse ionization chamber with a shielding grid [ru

The response-matrix based AFEN method for the hexagonal geometry

International Nuclear Information System (INIS)

Noh, Jae Man; Kim, Keung Koo; Zee, Sung Quun; Joo, Hyung Kook; Cho, Byng Oh; Jeong, Hyung Guk; Cho, Jin Young

1998-03-01

The analytic function expansion nodal (AFEN) method, developed to overcome the limitations caused by the transverse integration, has been successfully to predict the neutron behavior in the hexagonal core as well as rectangular core. In the hexagonal node, the transverse leakage resulted from the transverse integration has some singular terms such as delta-function and step-functions near the node center line. In most nodal methods using the transverse integration, the accuracy of nodal method is degraded because the transverse leakage is approximated as a smooth function across the node center line by ignoring singular terms. However, the AFEN method in which there is no transverse leakage term in deriving nodal coupling equations keeps good accuracy for hexagonal node. In this study, the AFEN method which shows excellent accuracy in the hexagonal core analyses is reformulated as a response matrix form. This form of the AFEN method can be implemented easily to nodal codes based on the response matrix method. Therefore, the Coarse Mesh Rebalance (CMR) acceleration technique which is one of main advantages of the response matrix method can be utilized for the AFEN method. The response matrix based AFEN method has been successfully implemented into the MASTER code and its accuracy and computational efficiency were examined by analyzing the two- and three- dimensional benchmark problem of VVER-440. Based on the results, it can be concluded that the newly formulated AFEN method predicts accurately the assembly powers (within 0.2% average error) as well as the effective multiplication factor (within 0.2% average error) as well as the effective multiplication factor (within 20 pcm error). In addition, the CMR acceleration technique is quite efficient in reducing the computation time of the AFEN method by 8 to 10 times. (author). 22 refs., 1 tab., 4 figs

Estimation of Covariance Matrix on Bi-Response Longitudinal Data Analysis with Penalized Spline Regression

Science.gov (United States)

Islamiyati, A.; Fatmawati; Chamidah, N.

2018-03-01

The correlation assumption of the longitudinal data with bi-response occurs on the measurement between the subjects of observation and the response. It causes the auto-correlation of error, and this can be overcome by using a covariance matrix. In this article, we estimate the covariance matrix based on the penalized spline regression model. Penalized spline involves knot points and smoothing parameters simultaneously in controlling the smoothness of the curve. Based on our simulation study, the estimated regression model of the weighted penalized spline with covariance matrix gives a smaller error value compared to the error of the model without covariance matrix.

Effects of mistuning and matrix structure on the topology of frequency response curves

Science.gov (United States)

Afolabi, Dare

1989-01-01

The stability of a frequency response curve under mild perturbations of the system's matrix is investigated. Using recent developments in the theory of singularities of differentiable maps, it is shown that the stability of a response curve depends on the structure of the system's matrix. In particular, the frequency response curves of a cylic system are shown to be unstable. Consequently, slight parameter variations engendered by mistuning will induce a significant difference in the topology of the forced response curves, if the mistuning transformation crosses the bifurcation set.

Linear and nonlinear response matrix and its application to the SIS18 synchrotron

International Nuclear Information System (INIS)

Parfenova, Angelina

2008-01-01

This Thesis is dedicated to the numerical as well as the experimental study of beam dynamics in circular accelerators. The experimental part was undertaken in the SIS18 synchrotron. The detailed description of the experiments contained in this work can be considered as a starting point for future experiments and machine development. The work has the following structure. In Chapter 2 an overview of the GSI and FAIR accelerator facilities, and a general description of the SIS18 instrumentation related to the study of this work are given. The expected SIS18 performance in view of the upgrade program for FAIR project are outlined. The main beam dynamics issues connected with the purpose of this work are discussed. Chapter 3 is devoted to the study of linear beam dynamics in the SIS18. The resonance beam loss measurements were carried out with residual gas profile monitor in the SIS18 (Chapter 4). In the frame of this work a novel technique 'nonlinear tune response matrix method' to identify strengths, polarities and locations of nonlinear errors in circular accelerators is developed (Chapter 5). In the method the feed down effect of the nonlinear components at level of linear tune response to the closed-orbit change is explored. The closed-orbit change is introduced by varying correction steerers. The tune values are retrieved from the spectrum of coherent betatron oscillations excited by a fast kick. The theoretical background, the robustness of the method and numerical examples for the SIS18 using numerical library MICROMAP are presented. The technique to measure lattice nonlinearities was experimentally validated in the SIS18 where two normal as well as two skew sextupolar errors of the order of natural errors were reconstructed with a tolerant precision. It was shown how this technique can be applied to reconstruct sextupolar nonlinear errors in the complete machine. In Chapter 6 the main results and the conclusions of this work are outlined. (orig.)

Matrix Metalloproteinase Responsive Delivery of Myostatin Inhibitors.

Science.gov (United States)

Braun, Alexandra C; Gutmann, Marcus; Ebert, Regina; Jakob, Franz; Gieseler, Henning; Lühmann, Tessa; Meinel, Lorenz

2017-01-01

The inhibition of myostatin - a member of the transforming growth factor (TGF-β) family - drives regeneration of functional skeletal muscle tissue. We developed a bioresponsive drug delivery system (DDS) linking release of a myostatin inhibitor (MI) to inflammatory flares of myositis to provide self-regulated MI concentration gradients within tissues of need. A protease cleavable linker (PCL) - responding to MMP upregulation - is attached to the MI and site-specifically immobilized on microparticle surfaces. The PCL disintegrated in a matrix metalloproteinase (MMP) 1, 8, and particularly MMP-9 concentration dependent manner, with MMP-9 being an effective surrogate biomarker correlating with the activity of myositis. The bioactivity of particle-surface bound as well as released MI was confirmed by luciferase suppression in stably transfected HEK293 cells responding to myostatin induced SMAD phosphorylation. We developed a MMP-responsive DDS for MI delivery responding to inflammatory flare of a diseased muscle matching the kinetics of MMP-9 upregulation, with MMP-9 kinetics matching (patho-) physiological myostatin levels. ᅟ: Graphical Abstract Schematic illustration of the matrix metalloproteinase responsive delivery system responding to inflammatory flares of muscle disease. The protease cleavable linker readily disintegrates upon entry into the diseased tissue, therby releasing the mystatin inhibitor.

Matrix isolation FT-IR spectroscopy and molecular orbital study of sarcosine methyl ester

Science.gov (United States)

Gómez-Zavaglia, A.; Fausto, R.

2004-02-01

N-methylglycine methyl ester (sarcosine-Me) has been studied by matrix isolation FT-IR spectroscopy and molecular orbital calculations undertaken at the DFT/B3LYP and MP2 levels of theory with the 6-311++G(d,p) and 6-31++G(d,p) basis set, respectively. Twelve different conformers were located in the potential energy surface of the studied compound, with the ASC conformer being the ground conformational state. This form is analogous to the dimethylglycine methyl ester most stable conformer and is characterized by a NH⋯O intramolecular hydrogen bond; in this form, the ester group assumes the cis configuration and the OC-C-N and Lp-N-C-C (where Lp is the nitrogen lone electron pair) dihedral angles are ca. -17.8 and 171.3°, respectively. The second most stable conformer ( GSC) differs from the ASC conformer essentially in the conformation assumed by the methylamino group, which in this case is gauche ( Lp-N-C-C dihedral angle equal to 79.4°). On the other hand, the third most stable conformer ( AAC) differs from the most stable form in the conformation of the OC-C-N axis (151.4°). These three forms were predicted to differ in energy by less than ca. 5 kJ mol -1 and represent ≈95% of the total conformational population at room temperature. FT-IR spectra were obtained for sarcosine-Me isolated in argon matrices (T=9 K) revealing the presence in the matrices of the three lowest energy conformers predicted by the calculations. The matrices were prepared by deposition of the vapour of the compound using two different nozzle temperatures, 25 and 60 °C. The relative populations of the three conformers trapped in the matrices were found to be consistent with occurrence of conformational cooling during matrix deposition and with a stabilization of the most polar GSC and AAC conformers in the matrices compared to the gas phase. Indeed, like it was previously observed for the methyl ester of dimethylglycine [Phys. Chem. Chem. Phys. 5 (2003) 52] the different

Methods of orbit correction system optimization

International Nuclear Information System (INIS)

Chao, Yu-Chiu.

1997-01-01

Extracting optimal performance out of an orbit correction system is an important component of accelerator design and evaluation. The question of effectiveness vs. economy, however, is not always easily tractable. This is especially true in cases where betatron function magnitude and phase advance do not have smooth or periodic dependencies on the physical distance. In this report a program is presented using linear algebraic techniques to address this problem. A systematic recipe is given, supported with quantitative criteria, for arriving at an orbit correction system design with the optimal balance between performance and economy. The orbit referred to in this context can be generalized to include angle, path length, orbit effects on the optical transfer matrix, and simultaneous effects on multiple pass orbits

Massively parallel red-black algorithms for x-y-z response matrix equations

International Nuclear Information System (INIS)

Hanebutte, U.R.; Laurin-Kovitz, K.; Lewis, E.E.

1992-01-01

Recently, both discrete ordinates and spherical harmonic (S n and P n ) methods have been cast in the form of response matrices. In x-y geometry, massively parallel algorithms have been developed to solve the resulting response matrix equations on the Connection Machine family of parallel computers, the CM-2, CM-200, and CM-5. These algorithms utilize two-cycle iteration on a red-black checkerboard. In this work we examine the use of massively parallel red-black algorithms to solve response matric equations in three dimensions. This longer term objective is to utilize massively parallel algorithms to solve S n and/or P n response matrix problems. In this exploratory examination, however, we consider the simple 6 x 6 response matrices that are derivable from fine-mesh diffusion approximations in three dimensions

A discrete ordinate response matrix method for massively parallel computers

International Nuclear Information System (INIS)

Hanebutte, U.R.; Lewis, E.E.

1991-01-01

A discrete ordinate response matrix method is formulated for the solution of neutron transport problems on massively parallel computers. The response matrix formulation eliminates iteration on the scattering source. The nodal matrices which result from the diamond-differenced equations are utilized in a factored form which minimizes memory requirements and significantly reduces the required number of algorithm utilizes massive parallelism by assigning each spatial node to a processor. The algorithm is accelerated effectively by a synthetic method in which the low-order diffusion equations are also solved by massively parallel red/black iterations. The method has been implemented on a 16k Connection Machine-2, and S 8 and S 16 solutions have been obtained for fixed-source benchmark problems in X--Y geometry

A simulation study of the global orbit feedback system for Pohang light source

International Nuclear Information System (INIS)

Kim, Kukhee; Shim, Kyuyeol; Cho, Moohyun; Namkung, Won; Ko, In Soo; Choi, Jinhyuk

2000-01-01

This paper describes the simulation of the global orbit feedback system using the singular value decomposition (SVD) method, the error minimization method, and the neural network method. Instead of facing unacceptable correction result raised occasionally in the SVD method, we choose the error minimization method for the global orbit feedback. This method provides minimum orbit errors while avoiding unacceptable corrections, and keeps the orbit within the dynamic aperture of the storage ring. We simulate the Pohang Light Source (PLS) storage ring using the Methodical Accelerator Design (MAD) code that generates the orbit distortions for the error minimization method and the learning data set for neural network method. In order to compare the effectiveness of the neural network method with others, a neural network is trained by the learning algorithm using the learning data set. The global response matrix with a minimum error and the trained neural network are used to the global orbit feedback system. The simulation shows that a selection of beam position monitors (BPMs) is very sensitive in the reduction of rms orbit distortions, and the random choice gives better results than any other cases. (author)

Finite orbit energetic particle linear response to toroidal Alfven eigenmodes

International Nuclear Information System (INIS)

Berk, H.L.; Ye, Huanchun; Breizman, B.N.

1991-07-01

The linear response of energetic particles to the TAE modes is calculated taking into account their finite orbit excursion from the flux surfaces. The general expression reproduces the previously derived theory for small banana width: when the banana width triangle b is much larger than the mode thickness triangle m , we obtain a new compact expression for the linear power transfer. When triangle m /triangle b much-lt 1, the banana orbit effect reduces the power transfer by a factor of triangle m /triangle b from that predicted by the narrow orbit theory. A comparison is made of the contribution to the TAE growth rate of energetic particles with a slowing-down distribution arising from an isotropic source, and a balance-injected beam source when the source speed is close to the Alfven speed. For the same stored energy density, the contribution from the principal resonances (|υ parallel | = υ A is substantially enhanced in the beam case compared to the isotropic case, while the contribution at the higher sidebands (|υ parallel |) = υ A /(2 ell - 1) with ell ≥ 2) is substantially reduced. 10 refs

ORBITAL INJURIES

Directory of Open Access Journals (Sweden)

Andrej Kansky

2002-12-01

Full Text Available Background. Orbit is involved in 40% of all facial fractures. There is considerable variety in severity, ranging from simple nondisplaced to complex comminuted fractures. Complex comminuted fractures (up to 20% are responsible for the majority of complications and unfavorable results. Orbital fractures are classified as internal orbital fractures, zygomatico-orbital fractures, naso-orbito-ethmoidal fractures and combined fractures. The ophtalmic sequelae of midfacial fractures are usually edema and ecchymosis of the soft tissues, subconjuctival hemorrhage, diplopia, iritis, retinal edema, ptosis, enophthalmos, ocular muscle paresis, mechanical restriction of ocular movement and nasolacrimal disturbances. More severe injuries such as optic nerve trauma and retinal detachments have also been reported. Within the wide range of orbital fractures small group of complex fractures causes most of the sequelae. Therefore identification of severe injuries and adequate treatment is of major importance. The introduction of craniofacial techniques made possible a wide exposure even of large orbital wall defects and their reconstruction by bone grafts. In spite of significant progress, repair of complex orbital wall defects remains a problem even for the experienced surgeons.Results. In 1999 121 facial injuries were treated at our department (Clinical Centre Ljubljana Dept. Of Maxillofacial and Oral Surgery. Orbit was involved in 65% of cases. Isolated inner orbital fractures presented 4% of all fractures. 17 (14% complex cases were treated, 5 of them being NOE, 5 orbital (frame and inner walls, 3 zygomatico-orbital, 2 FNO and 2 maxillo-orbital fractures.Conclusions. Final result of the surgical treatment depends on severity of maxillofacial trauma. Complex comminuted fractures are responsable for most of the unfavorable results and ocular function is often permanently damaged (up to 75% in these fractures.

Frozen orbit realization using LQR analogy

Science.gov (United States)

Nagarajan, N.; Rayan, H. Reno

In the case of remote sensing orbits, the Frozen Orbit concept minimizes altitude variations over a given region using passive means. This is achieved by establishing the mean eccentricity vector at the orbital poles i.e., by fixing the mean argument of perigee at 90 deg with an appropriate eccentricity to balance the perturbations due to zonal harmonics J2 and J3 of the Earth's potential. Eccentricity vector is a vector whose magnitude is the eccentricity and direction is the argument of perigee. The launcher dispersions result in an eccentricity vector which is away from the frozen orbit values. The objective is then to formulate an orbit maneuver strategy to optimize the fuel required to achieve the frozen orbit in the presence of visibility and impulse constraints. It is shown that the motion of the eccentricity vector around the frozen perigee can be approximated as a circle. Combining the circular motion of the eccentricity vector around the frozen point and the maneuver equation, the following discrete equation is obtained. X(k+1) = AX(k) + Bu(k), where X is the state (i.e. eccentricity vector components), A the state transition matrix, u the scalar control force (i.e. dV in this case) and B the control matrix which transforms dV into eccentricity vector change. Based on this, it is shown that the problem of optimizing the fuel can be treated as a Linear Quadratic Regulator (LQR) problem in which the maneuver can be solved by using control system design tools like MATLAB by deriving an analogy LQR design.

A 222 energy bins response matrix for a "6Lil scintillator Bss system

International Nuclear Information System (INIS)

Lacerda, M. A. S.; Vega C, H. R.; Mendez V, R.; Lorente F, A.; Ibanez F, S.; Gallego D, E.

2016-10-01

A new response matrix was calculated for a Bonner Sphere Spectrometer (Bss) with a "6Lil(Eu) scintillator. We utilized the Monte Carlo N-particle radiation transport code MCNPX, version 2.7.0, with Endf/B-VII.0 nuclear data library to calculate the responses for 6 spheres and the bare detector, for energies varying from 9.441 E(-10) MeV to 105.9 MeV, with 20 equal-log(E)-width bins per energy decade, totalizing 222 energy groups. A Bss, like the modeled in this work, was utilized to measure the neutron spectrum generated by the "2"4"1AmBe source of the Universidad Politecnica de Madrid. From the count rates obtained with this Bss system we unfolded neutron spectrum utilizing the BUNKIUT code for 31 energy bins (UTA-4 response matrix) and the MAXED code with the new calculated response functions. We compared spectra obtained with these Bss system / unfold codes with that obtained from measurements performed with a Bss system constituted of 12 spheres with a spherical "3He Sp-9 counter (Centronic Ltd., UK) and MAXED code with the system-specific response functions (Bss-CIEMAT). A relatively good agreement was observed between our response matrix and that calculated by other authors. In general, we observed an improvement in the agreement as the energy increases. However, higher discrepancies were observed for energies close to 1-E(-8) MeV and, mainly, for energies above 20 MeV. These discrepancies were mainly attributed to the differences in cross-section libraries employed. The ambient dose equivalent (H (10)) calculated with the "6Lil-MAXED showed a good agreement with values measured with the neutron area monitor Bert hold Lb 6411 and within 12% the value obtained with another Bss system (Bss-CIEMAT). The response matrix calculated in this work can be utilized together with the MAXED code to generate neutron spectra with a good energy resolution up to 20 MeV. Some additional tests are being done to validate this response matrix and improve the results for energies

The performance of a hybrid analytical-Monte Carlo system response matrix in pinhole SPECT reconstruction

International Nuclear Information System (INIS)

El Bitar, Z; Pino, F; Candela, C; Ros, D; Pavía, J; Rannou, F R; Ruibal, A; Aguiar, P

2014-01-01

It is well-known that in pinhole SPECT (single-photon-emission computed tomography), iterative reconstruction methods including accurate estimations of the system response matrix can lead to submillimeter spatial resolution. There are two different methods for obtaining the system response matrix: those that model the system analytically using an approach including an experimental characterization of the detector response, and those that make use of Monte Carlo simulations. Methods based on analytical approaches are faster and handle the statistical noise better than those based on Monte Carlo simulations, but they require tedious experimental measurements of the detector response. One suggested approach for avoiding an experimental characterization, circumventing the problem of statistical noise introduced by Monte Carlo simulations, is to perform an analytical computation of the system response matrix combined with a Monte Carlo characterization of the detector response. Our findings showed that this approach can achieve high spatial resolution similar to that obtained when the system response matrix computation includes an experimental characterization. Furthermore, we have shown that using simulated detector responses has the advantage of yielding a precise estimate of the shift between the point of entry of the photon beam into the detector and the point of interaction inside the detector. Considering this, it was possible to slightly improve the spatial resolution in the edge of the field of view. (paper)

A nodal method based on the response-matrix method

International Nuclear Information System (INIS)

Cunha Menezes Filho, A. da; Rocamora Junior, F.D.

1983-02-01

A nodal approach based on the Response-Matrix method is presented with the purpose of investigating the possibility of mixing two different allocations in the same problem. It is found that the use of allocation of albedo combined with allocation of direct reflection produces good results for homogeneous fast reactor configurations. (Author) [pt

ARE TIDAL EFFECTS RESPONSIBLE FOR EXOPLANETARY SPIN–ORBIT ALIGNMENT?

Energy Technology Data Exchange (ETDEWEB)

Li, Gongjie [Harvard-Smithsonian Center for Astrophysics, The Institute for Theory and Computation, 60 Garden Street, Cambridge, MA 02138 (United States); Winn, Joshua N., E-mail: gli@cfa.harvard.edu [Department of Physics, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139 (United States)

2016-02-10

The obliquities of planet-hosting stars are clues about the formation of planetary systems. Previous observations led to the hypothesis that for close-in giant planets, spin–orbit alignment is enforced by tidal interactions. Here, we examine two problems with this hypothesis. First, Mazeh and coworkers recently used a new technique—based on the amplitude of starspot-induced photometric variability—to conclude that spin–orbit alignment is common even for relatively long-period planets, which would not be expected if tides were responsible. We re-examine the data and find a statistically significant correlation between photometric variability and planetary orbital period that is qualitatively consistent with tidal interactions. However it is still difficult to explain quantitatively, as it would require tides to be effective for periods as long as tens of days. Second, Rogers and Lin argued against a particular theory for tidal re-alignment by showing that initially retrograde systems would fail to be re-aligned, in contradiction with the observed prevalence of prograde systems. We investigate a simple model that overcomes this problem by taking into account the dissipation of inertial waves and the equilibrium tide, as well as magnetic braking. We identify a region of parameter space where re-alignment can be achieved, but it only works for close-in giant planets, and requires some fine tuning. Thus, while we find both problems to be more nuanced than they first appeared, the tidal model still has serious shortcomings.

Extracellular matrix organization modulates fibroblast growth and growth factor responsiveness.

Science.gov (United States)

Nakagawa, S; Pawelek, P; Grinnell, F

1989-06-01

To learn more about the relationship between extracellular matrix organization, cell shape, and cell growth control, we studied DNA synthesis by fibroblasts in collagen gels that were either attached to culture dishes or floating in culture medium during gel contraction. After 4 days of contraction, the collagen density (initially 1.5 mg/ml) reached 22 mg/ml in attached gels and 55 mg/ml in floating gels. After contraction, attached collagen gels were well organized; collagen fibrils were aligned in the plane of cell spreading; and fibroblasts had an elongated, bipolar morphology. Floating collagen gels, however, were unorganized; collagen fibrils were arranged randomly; and fibroblasts had a stellate morphology. DNA synthesis by fibroblasts in contracted collagen gels was suppressed if the gels were floating in medium but not if the gels were attached, and inhibition was independent of the extent of gel contraction. Therefore, growth of fibroblasts in contracted collagen gels could be regulated by differences in extracellular matrix organization and cell shape independently of extracellular matrix density. We also compared the responses of fibroblasts in contracted collagen gels and monolayer culture to peptide growth factors including fibroblast growth factor, platelet-derived growth factor, transforming growth factor-beta, and interleukin 1. Cells in floating collagen gels were generally unresponsive to any of the growth factors. Cells in attached collagen gels and monolayer culture were affected similarly by fibroblast growth factor but not by the others. Our results indicate that extracellular matrix organization influenced not only cell growth, but also fibroblast responsiveness to peptide growth factors.

Global DC closed orbit correction experiments on the NSLS X-ray ring and SPEAR

International Nuclear Information System (INIS)

Chung, Y.; Decker, G.; Evans, K. Jr.; Safranek, J.; So, I.; Tang, Y.; Corbett, W.J.; Hettel, R.

1993-01-01

The global closed orbit correction experiments conducted on the NSLS X-ray ring and the SPEAR using the technique of singular value decomposition (SVD) are presented. The beam response matrix, defined as beam motion at beam position monitor (BPM) locations per unit kick by corrector magnets, was measured and then analyzed using SVD. The BPMs and correctors are reconfigured into open-quotes transformedclose quotes BPMs (t-BPMs) and open-quotes transformedclose quotes correctors (t-correctors), with each T-BPM coupled to at most one t-corrector and vice versa for orbit correction. The decoupled t-BPMs are used to estimate the limit on orbit correction, while the decoupled t-correctors are used to optimize the corrector strengths. As a result the vertical r.m.s. orbit error at the BPM locations was reduced from 208 μm to 61 μm about an arbitrary reference orbit in the NSLS X-ray ring. In SPEAR, the vertical closed orbit was brought to the BPM centers at the selected BPM locations with an r.m.s. error of 215 μm reduced from the initial 780 μm

Transverse impedance measurement using response matrix fit method at APS

International Nuclear Information System (INIS)

Sajaev, V.

2007-01-01

of an accelerator. The orbit bump method was done at BINP, APS, and ESRF. All these methods have one common feature: they employ the fact that the beam sees the impedance as an additional defocusing quadrupole whose strength depends on the beam current. At APS we use an orbit response matrix fit to determine the distribution of focusing errors around the machine, and then use these errors to calculate beta functions. Since the beam sees the impedance as a quadrupole whose strength depends on the beam current, the measurement of the beta functions with different currents could be used to determine the impedance distribution around the machine. This approach was first used at APS and reported in.

A method of orbital analysis for large-scale first-principles simulations

Energy Technology Data Exchange (ETDEWEB)

Ohwaki, Tsukuru [Advanced Materials Laboratory, Nissan Research Center, Nissan Motor Co., Ltd., 1 Natsushima-cho, Yokosuka, Kanagawa 237-8523 (Japan); Otani, Minoru [Nanosystem Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki 305-8568 (Japan); Ozaki, Taisuke [Research Center for Simulation Science (RCSS), Japan Advanced Institute of Science and Technology (JAIST), 1-1 Asahidai, Nomi, Ishikawa 923-1292 (Japan)

2014-06-28

An efficient method of calculating the natural bond orbitals (NBOs) based on a truncation of the entire density matrix of a whole system is presented for large-scale density functional theory calculations. The method recovers an orbital picture for O(N) electronic structure methods which directly evaluate the density matrix without using Kohn-Sham orbitals, thus enabling quantitative analysis of chemical reactions in large-scale systems in the language of localized Lewis-type chemical bonds. With the density matrix calculated by either an exact diagonalization or O(N) method, the computational cost is O(1) for the calculation of NBOs associated with a local region where a chemical reaction takes place. As an illustration of the method, we demonstrate how an electronic structure in a local region of interest can be analyzed by NBOs in a large-scale first-principles molecular dynamics simulation for a liquid electrolyte bulk model (propylene carbonate + LiBF{sub 4})

A method of orbital analysis for large-scale first-principles simulations

International Nuclear Information System (INIS)

Ohwaki, Tsukuru; Otani, Minoru; Ozaki, Taisuke

2014-01-01

An efficient method of calculating the natural bond orbitals (NBOs) based on a truncation of the entire density matrix of a whole system is presented for large-scale density functional theory calculations. The method recovers an orbital picture for O(N) electronic structure methods which directly evaluate the density matrix without using Kohn-Sham orbitals, thus enabling quantitative analysis of chemical reactions in large-scale systems in the language of localized Lewis-type chemical bonds. With the density matrix calculated by either an exact diagonalization or O(N) method, the computational cost is O(1) for the calculation of NBOs associated with a local region where a chemical reaction takes place. As an illustration of the method, we demonstrate how an electronic structure in a local region of interest can be analyzed by NBOs in a large-scale first-principles molecular dynamics simulation for a liquid electrolyte bulk model (propylene carbonate + LiBF 4 )

Schmidt-Kalman Filter with Polynomial Chaos Expansion for Orbit Determination of Space Objects

Science.gov (United States)

Yang, Y.; Cai, H.; Zhang, K.

2016-09-01

Parameter errors in orbital models can result in poor orbit determination (OD) using a traditional Kalman filter. One approach to account for these errors is to consider them in the so-called Schmidt-Kalman filter (SKF), by augmenting the state covariance matrix (CM) with additional parameter covariance rather than additively estimating these so-called "consider" parameters. This paper introduces a new SKF algorithm with polynomial chaos expansion (PCE-SKF). The PCE approach has been proved to be more efficient than Monte Carlo method for propagating the input uncertainties onto the system response without experiencing any constraints of linear dynamics, or Gaussian distributions of the uncertainty sources. The state and covariance needed in the orbit prediction step are propagated using PCE. An inclined geosynchronous orbit scenario is set up to test the proposed PCE-SKF based OD algorithm. The satellite orbit is propagated based on numerical integration, with the uncertain coefficient of solar radiation pressure considered. The PCE-SKF solutions are compared with extended Kalman filter (EKF), SKF and PCE-EKF (EKF with PCE) solutions. It is implied that the covariance propagation using PCE leads to more precise OD solutions in comparison with those based on linear propagation of covariance.

Weights assessment for orbit-on-demand vehicles

Science.gov (United States)

Macconochie, I. O.; Martin, J. A.; Breiner, C. A.; Cerro, J. A.

1985-01-01

Future manned, reusable earth-to-orbit vehicles may be required to reach orbit within hours or even minutes of a mission decision. A study has been conducted to consider vehicles with such a capability. In the initial phase of the study, 11 vehicles were sized for deployment of 5000 lbs to a polar orbit. From this matrix, two of the most promising concepts were resized for a modified mission and payload. A key feature of the study was the use of consistent mass estimating techniques for a broad range of concepts, allowing direct comparisons of sizes and weights.

The classical r-matrix method for nonlinear sigma-model

OpenAIRE

Sevostyanov, Alexey

1995-01-01

The canonical Poisson structure of nonlinear sigma-model is presented as a Lie-Poisson r-matrix bracket on coadjoint orbits. It is shown that the Poisson structure of this model is determined by some `hidden singularities' of the Lax matrix.

Ghost Imaging Using Orbital Angular Momentum

Institute of Scientific and Technical Information of China (English)

赵生妹; 丁建; 董小亮; 郑宝玉

2011-01-01

We present a novel encoding scheme in a ghost-imaging system using orbital angular momentum. In the signal arm, object spatial information is encoded as a phase matrix. For an N-grey-scale object, different phase matrices, varying from 0 to K with increment n/N, are used for different greyscales, and then they are modulated to a signal beam by a spatial light modulator. According to the conservation of the orbital angular momentum in the ghost imaging system, these changes will give different coincidence rates in measurement, and hence the object information can be extracted in the idler arm. By simulations and experiments, the results show that our scheme can improve the resolution of the image effectively. Compared with another encoding method using orbital angular momentum, our scheme has a better performance for both characters and the image object.%We present a novel encoding scheme in a ghost-imaging system using orbital angular momentum.In the signal arm,object spatial information is encoded as a phase matrix.For an N-grey-scale object,different phase matrices,varying from 0 to π with increment π/N,are used for different greyscales,and then they are modulated to a signal beam by a spatial light modulator.According to the conservation of the orbital angular momentum in the ghost imaging system,these changes will give different coincidence rates in measurement,and hence the object information can be extracted in the idler arm.By simulations and experiments,the results show that our scheme can improve the resolution of the image effectively.Compared with another encoding method using orbital angular momentum,our scheme has a better performance for both characters and the image object.

Effects of LDEF flight exposure on selected polymer matrix resin composite materials

Science.gov (United States)

Slemp, Wayne S.; Young, Philip R.; Witte, William G., Jr.; Shen, James Y.

1992-01-01

The characterization of selected graphite fiber reinforced epoxy (934 and 5208) and polysulfone (P1700) matrix resin composites materials which received over five years and nine months of exposure to the low earth orbit (LEO) environment in experiment AO134 on the Long Duration Exposure Facility is reported. The changes in mechanical properties of ultimate tensile strength and tensile modulus for exposed flight specimens are compared to the three sets of control specimens. Marked changes in surface appearance are discussed, and resin loss is reported. The chemical characterization including infrared, thermal, and selected solution property measurements showed that the molecular structure of the polymetric matrix had not changed significantly in response to this exposure.

Damping mathematical modelling and dynamic responses for FRP laminated composite plates with polymer matrix

Science.gov (United States)

Liu, Qimao

2018-02-01

This paper proposes an assumption that the fibre is elastic material and polymer matrix is viscoelastic material so that the energy dissipation depends only on the polymer matrix in dynamic response process. The damping force vectors in frequency and time domains, of FRP (Fibre-Reinforced Polymer matrix) laminated composite plates, are derived based on this assumption. The governing equations of FRP laminated composite plates are formulated in both frequency and time domains. The direct inversion method and direct time integration method for nonviscously damped systems are employed to solve the governing equations and achieve the dynamic responses in frequency and time domains, respectively. The computational procedure is given in detail. Finally, dynamic responses (frequency responses with nonzero and zero initial conditions, free vibration, forced vibrations with nonzero and zero initial conditions) of a FRP laminated composite plate are computed using the proposed methodology. The proposed methodology in this paper is easy to be inserted into the commercial finite element analysis software. The proposed assumption, based on the theory of material mechanics, needs to be further proved by experiment technique in the future.

A 222 energy bins response matrix for a {sup 6}Lil scintillator Bss system

Energy Technology Data Exchange (ETDEWEB)

Lacerda, M. A. S. [Centro de Desenvolvimento da Tecnologia Nuclear, Laboratorio de Calibracao de Dosimetros, Av. Pte. Antonio Carlos 6627, 31270-901 Pampulha, Belo Horizonte, Minas Gerais (Brazil); Vega C, H. R. [Universidad Autonoma de Zacatecas, Unidad Academica de Estudios Nucleares, Cipres No. 10, Fracc. La Penuela, 98068 Zacatecas, Zac. (Mexico); Mendez V, R. [Centro de Investigaciones Energeticas, Medioambientales y Tecnologicas, Laboratorio de Patrones Neutronicos, Av. Complutense 22, 28040 Madrid (Spain); Lorente F, A.; Ibanez F, S.; Gallego D, E., E-mail: masl@cdtn.br [Universidad Politecnica de Madrid, Departamento de Ingenieria Nuclear, 28006 Madrid (Spain)

2016-10-15

A new response matrix was calculated for a Bonner Sphere Spectrometer (Bss) with a {sup 6}Lil(Eu) scintillator. We utilized the Monte Carlo N-particle radiation transport code MCNPX, version 2.7.0, with Endf/B-VII.0 nuclear data library to calculate the responses for 6 spheres and the bare detector, for energies varying from 9.441 E(-10) MeV to 105.9 MeV, with 20 equal-log(E)-width bins per energy decade, totalizing 222 energy groups. A Bss, like the modeled in this work, was utilized to measure the neutron spectrum generated by the {sup 241}AmBe source of the Universidad Politecnica de Madrid. From the count rates obtained with this Bss system we unfolded neutron spectrum utilizing the BUNKIUT code for 31 energy bins (UTA-4 response matrix) and the MAXED code with the new calculated response functions. We compared spectra obtained with these Bss system / unfold codes with that obtained from measurements performed with a Bss system constituted of 12 spheres with a spherical {sup 3}He Sp-9 counter (Centronic Ltd., UK) and MAXED code with the system-specific response functions (Bss-CIEMAT). A relatively good agreement was observed between our response matrix and that calculated by other authors. In general, we observed an improvement in the agreement as the energy increases. However, higher discrepancies were observed for energies close to 1-E(-8) MeV and, mainly, for energies above 20 MeV. These discrepancies were mainly attributed to the differences in cross-section libraries employed. The ambient dose equivalent (H (10)) calculated with the {sup 6}Lil-MAXED showed a good agreement with values measured with the neutron area monitor Bert hold Lb 6411 and within 12% the value obtained with another Bss system (Bss-CIEMAT). The response matrix calculated in this work can be utilized together with the MAXED code to generate neutron spectra with a good energy resolution up to 20 MeV. Some additional tests are being done to validate this response matrix and improve the

Complex molecular orbital method: open-shell theory

International Nuclear Information System (INIS)

Hendekovic, J.

1976-01-01

A singe-determinant open-shell formalism for complex molecular orbitals is developed. An iterative algorithm for solving the resulting secular equations is constructed. It is based on a sequence of similarity transformations and matrix triangularizations

Evaluation of the synchrotron close orbit

International Nuclear Information System (INIS)

Bashmakov, Yu.A.; Karpov, V.A.

1991-01-01

The knowledge of the closed orbit position is an essential condition for the effective work of any accelerator. Therefore questions of calculations, measurements and controls have great importance. For example, during injection of particles into a synchrotron, the amplitudes of their betatron oscillations may become commensurable with the working region of the synchrotron. This makes one pay attention at the problem of formation of the optimum orbit with use of correcting optical elements. In addition, it is often necessary to calculate such an orbit at the end of the acceleration cycle when particles are deposited at internal targets or removed from the synchrotron. In this paper, the computation of the close orbit is reduced to a determination at an arbitrarily chosen azimuth of the eigenvector of the total transfer matrix of the synchrotron ring and to tracing with this vector desired orbit. The eigenvector is found as a result of an iteration

Alternative Method of On-Orbit Response-Versus-Scan-Angle Characterization for MODIS Reflective Solar Bands

Science.gov (United States)

Chen, Hongda; Xiong, Xiaoxiong; Angal, Amit; Geng, Xu; Wu, Aisheng

2016-01-01

The moderate resolution imaging spectroradiometer (MODIS) has 20 reflective solar bands (RSB), covering a spectral range from 0.41 to 2.2 microns, which are calibrated on-orbit using its onboard calibrators, which include a solar diffuser, a solar diffuser stability monitor, and a spectroradiometric calibration assembly. A space view (SV) port is used to provide a background reference and also facilitates near-monthly lunar observations through a spacecraft roll. In every scan, the Earth's surface, SV, and onboard calibrators are viewed via a two-sided scan mirror, the reflectance of which depends on the angle of incidence (AOI) as well as the wavelength of the incident light. Response-versus-scan-angle (RVS) is defined as a dependence function of the scan mirror's reflectance over AOI. An initial RVS for each RSB was measured prelaunch for both Terra and Aqua MODIS. Algorithms have been developed to track the on-orbit RVS variation using the measurements from the onboard calibrators, supplemented with the earth view (EV) trends from pseudoinvariant desert targets obtained at different AOI. Since the mission beginning, the MODIS characterization support team (MCST) has dedicated efforts in evaluating approaches of characterizing the on-orbit RVS. A majority of the approaches focused on fitting the data at each AOI over time and then deriving the relative change at different AOI. The current version of the on-orbit RVS algorithm, as implemented in the collection 6 (C6) level-1B (L1B), is also based on the above rationale. It utilizes the EV response trends from the pseudoinvariant Libyan desert targets to supplement the gain derived from the onboard calibrators. The primary limitation of this approach is the assumption of the temporal stability of these desert sites. Consequently, MCST developed an approach that derives the on-orbit RVS change using measurements from a single desert site, combined with the on-orbit lunar measurements. In addition, the EV and onboard

Nonlinear mechanical response of the extracellular matrix: learning from articular cartilage

Science.gov (United States)

Kearns, Sarah; Das, Moumita

2015-03-01

We study the mechanical structure-function relations in the extracellular matrix (ECM) with focus on nonlinear shear and compression response. As a model system, our study focuses on the ECM in articular cartilage tissue which has two major mechanobiological components: a network of the biopolymer collagen that acts as a stiff, reinforcing matrix, and a flexible aggrecan network that facilitates deformability. We model this system as a double network hydrogel made of interpenetrating networks of stiff and flexible biopolymers respectively. We study the linear and nonlinear mechanical response of the model ECM to shear and compression forces using a combination of rigidity percolation theory and energy minimization approaches. Our results may provide useful insights into the design principles of the ECM as well as biomimetic hydrogels that are mechanically robust and can, at the same time, easily adapt to cues in their surroundings.

ON-LINE NONLINEAR CHROMATICITY CORRECTION USING OFF-MOMENTUM TUNE RESPONSE MATRIX

International Nuclear Information System (INIS)

LUO, Y.; FISCHER, W.; MALISKY, N.; TEPIKIAN, S.; TROBJEVIC, D.

2007-01-01

In this article, we propose a method for the online nonlinear chromaticity correction at store in the Relativistic Heavy Ion Collider (RHIC). With 8 arc sextupole families in each RHIC ring, the nonlinear chromaticities can be minimized online by matching the off-momentum tunes onto the wanted tunes given by the linear chromaticities. The Newton method is used for this multi-dimensional nonlinear optimization, where the off-momentum tune response matrix with respect to sextupole strength changes is adopted. The off-momentum tune response matrix can be calculated with the online accelerator optics model or directly measured with the real beam. In this article, the correction algorithm for the RHIC is presented. Simulations are also carried out to verify the method. The preliminary results from the beam experiments taken place in the RHIC 2007 Au run are reviewed

A massively parallel discrete ordinates response matrix method for neutron transport

International Nuclear Information System (INIS)

Hanebutte, U.R.; Lewis, E.E.

1992-01-01

In this paper a discrete ordinates response matrix method is formulated with anisotropic scattering for the solution of neutron transport problems on massively parallel computers. The response matrix formulation eliminates iteration on the scattering source. The nodal matrices that result from the diamond-differenced equations are utilized in a factored form that minimizes memory requirements and significantly reduces the number of arithmetic operations required per node. The red-black solution algorithm utilizes massive parallelism by assigning each spatial node to one or more processors. The algorithm is accelerated by a synthetic method in which the low-order diffusion equations are also solved by massively parallel red-black iterations. The method is implemented on a 16K Connection Machine-2, and S 8 and S 16 solutions are obtained for fixed-source benchmark problems in x-y geometry

Use of regularization method in the determination of ring parameters and orbit correction

International Nuclear Information System (INIS)

Tang, Y.N.; Krinsky, S.

1993-01-01

We discuss applying the regularization method of Tikhonov to the solution of inverse problems arising in accelerator operations. This approach has been successfully used for orbit correction on the NSLS storage rings, and is presently being applied to the determination of betatron functions and phases from the measured response matrix. The inverse problem of differential equation often leads to a set of integral equations of the first kind which are ill-conditioned. The regularization method is used to combat the ill-posedness

A non-JKL density matrix functional for intergeminal correlation between closed-shell geminals from analysis of natural orbital configuration interaction expansions.

Science.gov (United States)

van Meer, R; Gritsenko, O V; Baerends, E J

2018-03-14

Almost all functionals that are currently used in density matrix functional theory have been created by some a priori ansatz that generates approximations to the second-order reduced density matrix (2RDM). In this paper, a more consistent approach is used: we analyze the 2RDMs (in the natural orbital basis) of rather accurate multi-reference configuration interaction expansions for several small molecules (CH 4 , NH 3 , H 2 O, FH, and N 2 ) and use the knowledge gained to generate new functionals. The analysis shows that a geminal-like structure is present in the 2RDMs, even though no geminal theory has been applied from the onset. It is also shown that the leading non-geminal dynamical correlation contributions are generated by a specific set of double excitations. The corresponding determinants give rise to non-JKL (non Coulomb/Exchange like) multipole-multipole dispersive attractive terms between geminals. Due to the proximity of the geminals, these dispersion terms are large and cannot be omitted, proving pure JKL functionals to be essentially deficient. A second correction emerges from the observation that the "normal" geminal-like exchange between geminals breaks down when one breaks multiple bonds. This problem can be fixed by doubling the exchange between bond broken geminals, effectively restoring the often physically correct high-spin configurations on the bond broken fragments. Both of these corrections have been added to the commonly used antisymmetrized product of strongly orthogonal geminals functional. The resulting non-JKL functional Extended Löwdin-Shull Dynamical-Multibond is capable of reproducing complete active space self-consistent field curves, in which one active orbital is used for each valence electron.

A non-JKL density matrix functional for intergeminal correlation between closed-shell geminals from analysis of natural orbital configuration interaction expansions

Science.gov (United States)

van Meer, R.; Gritsenko, O. V.; Baerends, E. J.

2018-03-01

Almost all functionals that are currently used in density matrix functional theory have been created by some a priori ansatz that generates approximations to the second-order reduced density matrix (2RDM). In this paper, a more consistent approach is used: we analyze the 2RDMs (in the natural orbital basis) of rather accurate multi-reference configuration interaction expansions for several small molecules (CH4, NH3, H2O, FH, and N2) and use the knowledge gained to generate new functionals. The analysis shows that a geminal-like structure is present in the 2RDMs, even though no geminal theory has been applied from the onset. It is also shown that the leading non-geminal dynamical correlation contributions are generated by a specific set of double excitations. The corresponding determinants give rise to non-JKL (non Coulomb/Exchange like) multipole-multipole dispersive attractive terms between geminals. Due to the proximity of the geminals, these dispersion terms are large and cannot be omitted, proving pure JKL functionals to be essentially deficient. A second correction emerges from the observation that the "normal" geminal-like exchange between geminals breaks down when one breaks multiple bonds. This problem can be fixed by doubling the exchange between bond broken geminals, effectively restoring the often physically correct high-spin configurations on the bond broken fragments. Both of these corrections have been added to the commonly used antisymmetrized product of strongly orthogonal geminals functional. The resulting non-JKL functional Extended Löwdin-Shull Dynamical-Multibond is capable of reproducing complete active space self-consistent field curves, in which one active orbital is used for each valence electron.

Orbital forcing of Arctic climate: mechanisms of climate response and implications for continental glaciation

Energy Technology Data Exchange (ETDEWEB)

Jackson, C S [Program in Atmospheric and Oceanic Sciences, Princeton University, NJ 08542, Princeton (United States); Institute for Geophysics, The John A. and Katherine G. Jackson School of Geosciences, The University of Texas at Austin, 4412 Spicewood Springs Rd., Bldg 600, TX 78759, Austin (United States); Broccoli, A J [NOAA/Geophysical Fluid Dynamics Laboratory, NJ 08542, Princeton (United States); Department of Environmental Sciences, Rutgers University, NJ 08903, New Brunswick (United States)

2003-12-01

Progress in understanding how terrestrial ice volume is linked to Earth's orbital configuration has been impeded by the cost of simulating climate system processes relevant to glaciation over orbital time scales (10{sup 3}-10{sup 5} years). A compromise is usually made to represent the climate system by models that are averaged over one or more spatial dimensions or by three-dimensional models that are limited to simulating particular ''snapshots'' in time. We take advantage of the short equilibration time ({proportional_to}10 years) of a climate model consisting of a three-dimensional atmosphere coupled to a simple slab ocean to derive the equilibrium climate response to accelerated variations in Earth's orbital configuration over the past 165,000 years. Prominent decreases in ice melt and increases in snowfall are simulated during three time intervals near 26, 73, and 117 thousand years ago (ka) when aphelion was in late spring and obliquity was low. There were also significant decreases in ice melt and increases in snowfall near 97 and 142 ka when eccentricity was relatively large, aphelion was in late spring, and obliquity was high or near its long term mean. These ''glaciation-friendly'' time intervals correspond to prominent and secondary phases of terrestrial ice growth seen within the marine {delta}{sup 18}O record. Both dynamical and thermal effects contribute to the increases in snowfall during these periods, through increases in storm activity and the fraction of precipitation falling as snow. The majority of the mid- to high latitude response to orbital forcing is organized by the properties of sea ice, through its influence on radiative feedbacks that nearly double the size of the orbital forcing as well as its influence on the seasonal evolution of the latitudinal temperature gradient. (orig.)

1ST-ORDER NONADIABATIC COUPLING MATRIX-ELEMENTS FROM MULTICONFIGURATIONAL SELF-CONSISTENT-FIELD RESPONSE THEORY

DEFF Research Database (Denmark)

Bak, Keld L.; Jørgensen, Poul; Jensen, H.J.A.

1992-01-01

A new scheme for obtaining first-order nonadiabatic coupling matrix elements (FO-NACME) for multiconfigurational self-consistent-field (MCSCF) wave functions is presented. The FO-NACME are evaluated from residues of linear response functions. The residues involve the geometrical response of a ref......A new scheme for obtaining first-order nonadiabatic coupling matrix elements (FO-NACME) for multiconfigurational self-consistent-field (MCSCF) wave functions is presented. The FO-NACME are evaluated from residues of linear response functions. The residues involve the geometrical response...... to the full configuration interaction limit. Comparisons are made with state-averaged MCSCF results for MgH2 and finite-difference configuration interaction by perturbation with multiconfigurational zeroth-order wave function reflected by interactive process (CIPSI) results for BH....

Radial Matrix Elements of Hydrogen Atom and the Correspondence ...

Indian Academy of Sciences (India)

R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

Hydrogen excited states—radial matrix element—corres- ... atoms, its availability, production, its spectras, and importance in astrophysics (Dupree ... far away revolving lazily around in a slow orbit like a distant planet in the solar system. As the electron orbit diameter grows rapidly, its energy also decreases rapidly. Currently ...

Damping mathematical modelling and dynamic responses for FRP laminated composite plates with polymer matrix

Directory of Open Access Journals (Sweden)

Liu Qimao

2018-02-01

Full Text Available This paper proposes an assumption that the fibre is elastic material and polymer matrix is viscoelastic material so that the energy dissipation depends only on the polymer matrix in dynamic response process. The damping force vectors in frequency and time domains, of FRP (Fibre-Reinforced Polymer matrix laminated composite plates, are derived based on this assumption. The governing equations of FRP laminated composite plates are formulated in both frequency and time domains. The direct inversion method and direct time integration method for nonviscously damped systems are employed to solve the governing equations and achieve the dynamic responses in frequency and time domains, respectively. The computational procedure is given in detail. Finally, dynamic responses (frequency responses with nonzero and zero initial conditions, free vibration, forced vibrations with nonzero and zero initial conditions of a FRP laminated composite plate are computed using the proposed methodology. The proposed methodology in this paper is easy to be inserted into the commercial finite element analysis software. The proposed assumption, based on the theory of material mechanics, needs to be further proved by experiment technique in the future.

Finite orbit energetic particle linear response to toroidal Alfven eigenmodes

International Nuclear Information System (INIS)

Berk, H.L.; Ye Huanchun; Breizman, B.N.

1992-01-01

The linear response of energetic particles of the TAE modes is calculated taking into account their finite orbit excursion from the flux surfaces. The general expression reproduces the previously derived theory for small banana width; when the banana width Δ b is much larger than the mode thickness Δ m , we obtain a new compact expression for the linear power transfer. When Δ m /Δ b m /Δ b from that predicted by the narrow orbit theory. A comparison is made of the contribution to the TAE growth rate of energetic particles with a slowing-down distribution arising from an isotropic source, and a balanced-injected beam source when the source speed is close to the Alfven speed. For the same stored energy density, the contribution from the principal resonances (vertical strokev parallel vertical stroke=v A ) is substantially enhanced in the beam case compared to the isotropic case, while the contribution at the higher sidebands (vertical strokev parallel vertical stroke=v A /(2l-1) with l≥2) is substantially reduced. (orig.)

New computational method for non-LTE, the linear response matrix

International Nuclear Information System (INIS)

Fournier, K.B.; Grasiani, F.R.; Harte, J.A.; Libby, S.B.; More, R.M.; Zimmerman, G.B.

1998-01-01

My coauthors have done extensive theoretical and computational calculations that lay the ground work for a linear response matrix method to calculate non-LTE (local thermodynamic equilibrium) opacities. I will give briefly review some of their work and list references. Then I will describe what has been done to utilize this theory to create a computational package to rapidly calculate mild non-LTE emission and absorption opacities suitable for use in hydrodynamic calculations. The opacities are obtained by performing table look-ups on data that has been generated with a non-LTE package. This scheme is currently under development. We can see that it offers a significant computational speed advantage. It is suitable for mild non-LTE, quasi-steady conditions. And it offers a new insertion path for high-quality non-LTE data. Currently, the linear response matrix data file is created using XSN. These data files could be generated by more detailed and rigorous calculations without changing any part of the implementation in the hydro code. The scheme is running in Lasnex and is being tested and developed

Symmetries of integrable hierarchies and matrix model constraints

International Nuclear Information System (INIS)

Vos, K. de

1992-01-01

The orbit construction associates a soliton hierarchy to every level-one vertex realization of a simply laced affine Kac-Moody algebra g. We show that the τ-function of such a hierarchy has the (truncated) Virasoro algebra as an algebra of infinitesimal symmetry transformations. To prove this we use an appropriate bilinear form of these hierarchies together with the coset construction of conformal field theory. For A 1 (1) the orbit construction gives either the Toda or the KdV hierarchy. These both occur in the one-matrix model of two-dimensional quantum gravity, before and after the double scaling limit respectively. The truncated Virasoro symmetry algebra is exactly the algebra of constraints of the one-matrix model. The partition function of the one-matrix model is therefore an invariant τ-function. We also consider the case of A 1 (1) with l>1. Surprisingly, the symmetry algebra in that case is not simply a truncated Casimir algebra. It appears that again only the Virasoro symmetry survives. We speculate on the relation with multi-matrix models. (orig.)

Response matrix calculation of a Bonner Sphere Spectrometer using ENDF/B-VII libraries

Energy Technology Data Exchange (ETDEWEB)

Morató, Sergio; Juste, Belén; Miró, Rafael; Verdú, Gumersindo [Instituto de Seguridad Industrial, Radiofísica y Medioambiental (ISIRYM), Universitat Politècnica de València (Spain); Guardia, Vicent, E-mail: bejusvi@iqn.upv.es [GD Energy Services, Valencia (Spain). Grupo dominguis

2017-07-01

The present work is focused on the reconstruction of a neutron spectra using a multisphere spectrometer also called Bonner Spheres System (BSS). To that, the determination of the response detector curves is necessary therefore we have obtained the response matrix of a neutron detector by Monte Carlo (MC) simulation with MCNP6 where the use of unstructured mesh geometries is introduced as a novelty. The aim of these curves was to study the theoretical response of a widespread neutron spectrometer exposed to neutron radiation. A neutron detector device has been used in this work which is formed by a multispheres spectrometer (BSS) that uses 6 high density polyethylene spheres with different diameters. The BSS consists of a set of 0.95 g/cm{sup 3} high density polyethylene spheres. The detector is composed of a lithium iodide 6LiI cylindrical scintillator crystal 4mm x 4mm size LUDLUM Model 42 coupled to a photomultiplier tube. Thermal tables are required to include polyethylene cross section in the simulation. These data are essential to get correct and accurate results in problems involving neutron thermalization. Nowadays available literature present the response matrix calculated with ENDF.B.V cross section libraries (V.Mares et al 1993) or with ENDF.B.VI (R.Vega Carrillo et al 2007). This work uses two novelties to calculate the response matrix. On the one hand the use of unstructured meshes to simulate the geometry of the detector and the Bonner Spheres and on the other hand the use of the updated ENDF.B.VII cross sections libraries. A set of simulations have been performed to obtain the detector response matrix. 29 mono energetic neutron beams between 10 KeV to 20 MeV were used as source for each moderator sphere up to a total of 174 simulations. Each mono energetic source was defined with the same diameter as the moderating sphere used in its corresponding simulation and the spheres were uniformly irradiated from the top of the photomultiplier tube. Some

Introducing Earth's Orbital Eccentricity

Science.gov (United States)

Oostra, Benjamin

2015-01-01

Most students know that planetary orbits, including Earth's, are elliptical; that is Kepler's first law, and it is found in many science textbooks. But quite a few are mistaken about the details, thinking that the orbit is very eccentric, or that this effect is somehow responsible for the seasons. In fact, the Earth's orbital eccentricity is…

A Detailed Derivation of Gaussian Orbital-Based Matrix Elements in Electron Structure Calculations

Science.gov (United States)

Petersson, T.; Hellsing, B.

2010-01-01

A detailed derivation of analytic solutions is presented for overlap, kinetic, nuclear attraction and electron repulsion integrals involving Cartesian Gaussian-type orbitals. It is demonstrated how s-type orbitals can be used to evaluate integrals with higher angular momentum via the properties of Hermite polynomials and differentiation with…

Single-particle Glauber matrix elements

International Nuclear Information System (INIS)

Oset, E.; Strottman, D.

1983-01-01

The single-particle matrix elements of the Glauber profile function are tabulated for harmonic oscillator single-particle wave functions. The tables are presented in such a manner as to be applicable if the hadron--nucleon elementary scattering amplitude is specified by either a partial wave expansion or a Gaussian in momentum transfer squared. The table is complete through the 1 g/sub 9/2/ orbital and contains entries for the 3s/sub 1/2/ orbital for use if realistic wave functions are expanded in terms of harmonic oscillator functions

Fermi Surface of Sr_{2}RuO_{4}: Spin-Orbit and Anisotropic Coulomb Interaction Effects.

Science.gov (United States)

Zhang, Guoren; Gorelov, Evgeny; Sarvestani, Esmaeel; Pavarini, Eva

2016-03-11

The topology of the Fermi surface of Sr_{2}RuO_{4} is well described by local-density approximation calculations with spin-orbit interaction, but the relative size of its different sheets is not. By accounting for many-body effects via dynamical mean-field theory, we show that the standard isotropic Coulomb interaction alone worsens or does not correct this discrepancy. In order to reproduce experiments, it is essential to account for the Coulomb anisotropy. The latter is small but has strong effects; it competes with the Coulomb-enhanced spin-orbit coupling and the isotropic Coulomb term in determining the Fermi surface shape. Its effects are likely sizable in other correlated multiorbital systems. In addition, we find that the low-energy self-energy matrix-responsible for the reshaping of the Fermi surface-sizably differs from the static Hartree-Fock limit. Finally, we find a strong spin-orbital entanglement; this supports the view that the conventional description of Cooper pairs via factorized spin and orbital part might not apply to Sr_{2}RuO_{4}.

Solution of the Multigroup-Diffusion equation by the response matrix method

International Nuclear Information System (INIS)

Oliveira, C.R.E.

1980-10-01

A preliminary analysis of the response matrix method is made, considering its application to the solution of the multigroup diffusion equations. The one-dimensional formulation is presented and used to test some flux expansions, seeking the application of the method to the two-dimensional problem. This formulation also solves the equations that arise from the integro-differential synthesis algorithm. The slow convergence of the power method, used to solve the eigenvalue problem, and its acceleration by means of the Chebyshev polynomial method, are also studied. An algorithm for the estimation of the dominance ratio is presented, based on the residues of two successive iteration vectors. This ratio, which is not known a priori, is fundamental for the efficiency of the method. Some numerical problems are solved, testing the 1D formulation of the response matrix method, its application to the synthesis algorithm and also, at the same time, the algorithm to accelerate the source problem. (Author) [pt

Composite Materials With Uncured Epoxy Matrix Exposed in Stratosphere During NASA Stratospheric Balloon Flight

Science.gov (United States)

Kondyurin, Alexey; Kondyurina, Irina; Bilek, Marcela; de Groh, Kim K.

2013-01-01

A cassette of uncured composite materials with epoxy resin matrixes was exposed in the stratosphere (40 km altitude) over three days. Temperature variations of -76 to 32.5C and pressure up to 2.1 torr were recorded during flight. An analysis of the chemical structure of the composites showed, that the polymer matrix exposed in the stratosphere becomes crosslinked, while the ground control materials react by way of polymerization reaction of epoxy groups. The space irradiations are considered to be responsible for crosslinking of the uncured polymers exposed in the stratosphere. The composites were cured on Earth after landing. Analysis of the cured composites showed that the polymer matrix remains active under stratospheric conditions. The results can be used for predicting curing processes of polymer composites in a free space environment during an orbital space flight.

Association of Clinical Response and Long-term Outcome Among Patients With Biopsied Orbital Pseudotumor Receiving Modern Radiation Therapy

Energy Technology Data Exchange (ETDEWEB)

Prabhu, Roshan S., E-mail: rprabhu@emory.edu [Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia (United States); Kandula, Shravan; Liebman, Lang [Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia (United States); Wojno, Ted H.; Hayek, Brent [Division of Oculoplastics, Orbital and Cosmetic Surgery, Emory University, Atlanta, Georgia (United States); Hall, William A.; Shu, Hui-Kuo; Crocker, Ian [Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia (United States)

2013-03-01

Purpose: To retrospectively evaluate institutional outcomes for patients treated with modern radiation therapy (RT) for biopsied orbital pseudotumor (OP). Methods and Materials: Twenty patients (26 affected orbits) with OP were treated with RT between January 2002 and December 2011. All patients underwent biopsy with histopathologic exclusion of other disease processes. Sixteen patients (80%) were treated with intensity modulated RT, 3 (15%) with opposed lateral beams, and 1 (5%) with electrons. Median RT dose was 27 Gy (range 25.2-30.6 Gy). Response to RT was evaluated at 4 months post-RT. Partial response (PR) was defined as improvement in orbital symptoms without an increase in steroid dose. Complete response (CR) 1 and CR 2 were defined as complete resolution of orbital symptoms with reduction in steroid dose (CR 1) or complete tapering of steroids (CR 2). The median follow-up period was 18.6 months (range 4-81.6 months). Results: Seventeen patients (85%) demonstrated response to RT, with 7 (35%), 1 (5%), and 9 (45%) achieving a PR, CR 1, and CR 2, respectively. Of the 17 patients who had ≥PR at 4 months post-RT, 6 (35%) experienced recurrence of symptoms. Age (>46 years vs ≤46 years, P=.04) and clinical response to RT (CR 2 vs CR 1/PR, P=.05) were significantly associated with pseudotumor recurrence. Long-term complications were seen in 7 patients (35%), including 4 with cataract formation, 1 with chronic dry eye, 1 with enophthalmos, and 1 with keratopathy. Conclusions: RT is an effective treatment for improving symptoms and tapering steroids in patients with a biopsy supported diagnosis of OP. Older age and complete response to RT were associated with a significantly reduced probability of symptom recurrence. The observed late complications may be related to RT, chronic use of steroids/immunosuppressants, medical comorbidities, or combination of factors.

Association of Clinical Response and Long-term Outcome Among Patients With Biopsied Orbital Pseudotumor Receiving Modern Radiation Therapy

International Nuclear Information System (INIS)

Prabhu, Roshan S.; Kandula, Shravan; Liebman, Lang; Wojno, Ted H.; Hayek, Brent; Hall, William A.; Shu, Hui-Kuo; Crocker, Ian

2013-01-01

Purpose: To retrospectively evaluate institutional outcomes for patients treated with modern radiation therapy (RT) for biopsied orbital pseudotumor (OP). Methods and Materials: Twenty patients (26 affected orbits) with OP were treated with RT between January 2002 and December 2011. All patients underwent biopsy with histopathologic exclusion of other disease processes. Sixteen patients (80%) were treated with intensity modulated RT, 3 (15%) with opposed lateral beams, and 1 (5%) with electrons. Median RT dose was 27 Gy (range 25.2-30.6 Gy). Response to RT was evaluated at 4 months post-RT. Partial response (PR) was defined as improvement in orbital symptoms without an increase in steroid dose. Complete response (CR) 1 and CR 2 were defined as complete resolution of orbital symptoms with reduction in steroid dose (CR 1) or complete tapering of steroids (CR 2). The median follow-up period was 18.6 months (range 4-81.6 months). Results: Seventeen patients (85%) demonstrated response to RT, with 7 (35%), 1 (5%), and 9 (45%) achieving a PR, CR 1, and CR 2, respectively. Of the 17 patients who had ≥PR at 4 months post-RT, 6 (35%) experienced recurrence of symptoms. Age (>46 years vs ≤46 years, P=.04) and clinical response to RT (CR 2 vs CR 1/PR, P=.05) were significantly associated with pseudotumor recurrence. Long-term complications were seen in 7 patients (35%), including 4 with cataract formation, 1 with chronic dry eye, 1 with enophthalmos, and 1 with keratopathy. Conclusions: RT is an effective treatment for improving symptoms and tapering steroids in patients with a biopsy supported diagnosis of OP. Older age and complete response to RT were associated with a significantly reduced probability of symptom recurrence. The observed late complications may be related to RT, chronic use of steroids/immunosuppressants, medical comorbidities, or combination of factors

The effect of the food matrix on In Vivo immune responses to purified peanut allergens

NARCIS (Netherlands)

Wijk, F. van; Nierkens, S.; Hassing, I.; Feijen, M.; Koppelman, S.J.; Jong, G.A.H. de; Pieters, R.; Knippels, L.M.J.

2005-01-01

There is little knowledge about the factors that determine the allergenicity of food proteins. One aspect that remains to be elucidated is the effect of the food matrix on immune responses to food proteins. To study the intrinsic immunogenicity of allergens and the influence of the food matrix,

The effect of the food matrix on in vivo immune responses to purified peanut allergens.

NARCIS (Netherlands)

Wijk, F. van; Nierkens, S.; Hassing, I.; Feijen, M.; Koppelman, S.J.; Jong, G.A. de; Pieters, R.; Knippels, L.M.

2005-01-01

There is little knowledge about the factors that determine the allergenicity of food proteins. One aspect that remains to be elucidated is the effect of the food matrix on immune responses to food proteins. To study the intrinsic immunogenicity of allergens and the influence of the food matrix,

Stationary D = 4 black holes in supergravity: The issue of real nilpotent orbits

Energy Technology Data Exchange (ETDEWEB)

Ruggeri, Daniele [Universita di Torino, Dipartimento di Fisica (Italy); INFN, Torino (Italy); Trigiante, Mario [Universita di Torino, Dipartimento di Fisica (Italy); DISAT, Politecnico di Torino (Italy); INFN, Torino (Italy)

2017-05-15

The complete classification of the nilpotent orbits of SO(2,2){sup 2} in the representation (2,2,2,2), achieved in [14], is applied to the study of multi-center, asymptotically flat, extremal black hole solutions to the STU model. These real orbits provide an intrinsic characterization of regular single-center solutions, which is invariant with respect to the action of the global symmetry group SO(4,4), underlying the stationary solutions of the model, and provide stringent regularity constraints on multi-centered solutions. The known almost-BPS and composite non-BPS solutions are revisited in this setting. We systematically provide, for the relevant SO(2,2){sup 2}-nilpotent orbits of the global Noether charge matrix, regular representatives thereof. This analysis unveils a composition law of the orbits according to which those containing regular multi-centered solutions can be obtained as combinations of specific single-center orbits defining the constituent black holes. Some of the SO(2,2){sup 2}-orbits of the total Noether charge matrix are characterized as ''intrinsically singular'' in that they cannot contain any regular solution. (copyright 2017 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

The nuclear spin-orbit coupling

International Nuclear Information System (INIS)

Bell, J.S.; Skyrme, T.H.R.

1994-01-01

Analysis of the nucleon-nucleon scattering around 100 MeV has determined the spin-orbit coupling part of the two-body scattering matrix at that energy, and a reasonable extrapolation to lower energies is possible. This scattering amplitude has been used, in the spirit of Brueckner's nuclear model, to estimate the resultant single-body spin-orbit coupling for a single nucleon interacting with a large nucleus. This resultant potential has a radial dependence approximately proportional to r -1 d ρ /dr, and with a magnitude in good agreement with that required to explain the doublet splittings in nuclei and the polarization of nucleons scattered elastically off nuclei. (author). 14 refs, 2 figs

Visualizing phase transition behavior of dilute stimuli responsive polymer solutions via Mueller matrix polarimetry.

Science.gov (United States)

Narayanan, Amal; Chandel, Shubham; Ghosh, Nirmalya; De, Priyadarsi

2015-09-15

Probing volume phase transition behavior of superdiluted polymer solutions both micro- and macroscopically still persists as an outstanding challenge. In this regard, we have explored 4 × 4 spectral Mueller matrix measurement and its inverse analysis for excavating the microarchitectural facts about stimuli responsiveness of "smart" polymers. Phase separation behavior of thermoresponsive poly(N-isopropylacrylamide) (PNIPAM) and pH responsive poly(N,N-(dimethylamino)ethyl methacrylate) (PDMAEMA) and their copolymers were analyzed in terms of Mueller matrix derived polarization parameters, namely, depolarization (Δ), diattenuation (d), and linear retardance (δ). The Δ, d, and δ parameters provided useful information on both macro- and microstructural alterations during the phase separation. Additionally, the two step action ((i) breakage of polymer-water hydrogen bonding and (ii) polymer-polymer aggregation) at the molecular microenvironment during the cloud point generation was successfully probed via these parameters. It is demonstrated that, in comparison to the present techniques available for assessing the hydrophobic-hydrophilic switch over of simple stimuli-responsive polymers, Mueller matrix polarimetry offers an important advantage requiring a few hundred times dilute polymer solution (0.01 mg/mL, 1.1-1.4 μM) at a low-volume format.

Optical-limiting response of rare-earth metallo-phthalocyanine-doped copolymer matrix

NARCIS (Netherlands)

Aneeshkumar, B.N.; Gopinath, P.; Vallabhan, C.P.G.; Nampoori, V.P.N.; Radhakrishnan, P.; Thomas, J.

2003-01-01

The nanosecond optical-limiting characteristics (at 532 nm) of some rare-earth metallo-phthalocyanines (Sm(Pc)2, Eu(Pc)2, and LaPc) doped in a copolymer matrix of poly(Me methacrylate) and Me-2-cyanoacrylate were studied for the 1st time to the authors' knowledge. The optical-limiting response is

Novel load responsive multilayer insulation with high in-atmosphere and on-orbit thermal performance

Science.gov (United States)

Dye, S.; Kopelove, A.; Mills, G. L.

2012-04-01

Aerospace cryogenic systems require lightweight, high performance thermal insulation to preserve cryopropellants both pre-launch and on-orbit. Current technologies have difficulty meeting all requirements, and advances in insulation would benefit cryogenic upper stage launch vehicles, LH2 fueled aircraft and ground vehicles, and provide capabilities for sub-cooled cryogens for space-borne instruments and orbital fuel depots. This paper reports the further development of load responsive multilayer insulation (LRMLI) that has a lightweight integrated vacuum shell and provides high thermal performance both in-air and on-orbit. LRMLI is being developed by Quest Product Development and Ball Aerospace under NASA contract, with prototypes designed, built, installed and successfully tested. A 3-layer LRMLI blanket (0.63 cm thick, 77 K cold, 295 K hot) had a measured heat leak of 6.6 W/m2 in vacuum and 40.6 W/m2 in air at one atmosphere. In-air LRMLI has an 18× advantage over Spray On Foam Insulation (SOFI) in heat leak per thickness and a 16× advantage over aerogel. On-orbit LRMLI has a 78× lower heat leak than SOFI per thickness and 6× lower heat leak than aerogel. The Phase II development of LRMLI is reported with a modular, flexible, thin vacuum shell and improved on-orbit performance. Structural and thermal analysis and testing results are presented. LRMLI mass and thermal performance is compared to SOFI, aerogel and MLI over SOFI.

Spin-orbital quantum liquid on the honeycomb lattice

Science.gov (United States)

Corboz, Philippe

2013-03-01

The symmetric Kugel-Khomskii can be seen as a minimal model describing the interactions between spin and orbital degrees of freedom in transition-metal oxides with orbital degeneracy, and it is equivalent to the SU(4) Heisenberg model of four-color fermionic atoms. We present simulation results for this model on various two-dimensional lattices obtained with infinite projected-entangled pair states (iPEPS), an efficient variational tensor-network ansatz for two dimensional wave functions in the thermodynamic limit. This approach can be seen as a two-dimensional generalization of matrix product states - the underlying ansatz of the density matrix renormalization group method. We find a rich variety of exotic phases: while on the square and checkerboard lattices the ground state exhibits dimer-Néel order and plaquette order, respectively, quantum fluctuations on the honeycomb lattice destroy any order, giving rise to a spin-orbital liquid. Our results are supported from flavor-wave theory and exact diagonalization. Furthermore, the properties of the spin-orbital liquid state on the honeycomb lattice are accurately accounted for by a projected variational wave-function based on the pi-flux state of fermions on the honeycomb lattice at 1/4-filling. In that state, correlations are algebraic because of the presence of a Dirac point at the Fermi level, suggesting that the ground state is an algebraic spin-orbital liquid. This model provides a good starting point to understand the recently discovered spin-orbital liquid behavior of Ba3CuSb2O9. The present results also suggest to choose optical lattices with honeycomb geometry in the search for quantum liquids in ultra-cold four-color fermionic atoms. We acknowledge the financial support from the Swiss National Science Foundation.

Polarized atomic orbitals for linear scaling methods

Science.gov (United States)

Berghold, Gerd; Parrinello, Michele; Hutter, Jürg

2002-02-01

We present a modified version of the polarized atomic orbital (PAO) method [M. S. Lee and M. Head-Gordon, J. Chem. Phys. 107, 9085 (1997)] to construct minimal basis sets optimized in the molecular environment. The minimal basis set derives its flexibility from the fact that it is formed as a linear combination of a larger set of atomic orbitals. This approach significantly reduces the number of independent variables to be determined during a calculation, while retaining most of the essential chemistry resulting from the admixture of higher angular momentum functions. Furthermore, we combine the PAO method with linear scaling algorithms. We use the Chebyshev polynomial expansion method, the conjugate gradient density matrix search, and the canonical purification of the density matrix. The combined scheme overcomes one of the major drawbacks of standard approaches for large nonorthogonal basis sets, namely numerical instabilities resulting from ill-conditioned overlap matrices. We find that the condition number of the PAO overlap matrix is independent from the condition number of the underlying extended basis set, and consequently no numerical instabilities are encountered. Various applications are shown to confirm this conclusion and to compare the performance of the PAO method with extended basis-set calculations.

Magnetic response from a composite of metal-dielectric particles in the visible range: T-matrix simulation

Directory of Open Access Journals (Sweden)

O. Zhuromskyy

2011-09-01

Full Text Available The optical response of a particle composed of a dielectric core surrounded by a densely packed shell of small metal spheres is simulated with the superposition Tmatrix method for realistic material parameters. In order to compute the electric and magnetic particle polarizabilities a single expansion T-matrix is derived from a particle centered T-matrix. Finally the permeability of a medium comprising such particles is found to deviate considerable from unity resulting in a noticeable optical response.

Periodic orbits around areostationary points in the Martian gravity field

International Nuclear Information System (INIS)

Liu Xiaodong; Baoyin Hexi; Ma Xingrui

2012-01-01

This study investigates the problem of areostationary orbits around Mars in three-dimensional space. Areostationary orbits are expected to be used to establish a future telecommunication network for the exploration of Mars. However, no artificial satellites have been placed in these orbits thus far. The characteristics of the Martian gravity field are presented, and areostationary points and their linear stability are calculated. By taking linearized solutions in the planar case as the initial guesses and utilizing the Levenberg-Marquardt method, families of periodic orbits around areostationary points are shown to exist. Short-period orbits and long-period orbits are found around linearly stable areostationary points, but only short-period orbits are found around unstable areostationary points. Vertical periodic orbits around both linearly stable and unstable areostationary points are also examined. Satellites in these periodic orbits could depart from areostationary points by a few degrees in longitude, which would facilitate observation of the Martian topography. Based on the eigenvalues of the monodromy matrix, the evolution of the stability index of periodic orbits is determined. Finally, heteroclinic orbits connecting the two unstable areostationary points are found, providing the possibility for orbital transfer with minimal energy consumption.

Intermediate-band photosensitive device with quantum dots having tunneling barrier embedded in organic matrix

Science.gov (United States)

Forrest, Stephen R.

2008-08-19

A plurality of quantum dots each have a shell. The quantum dots are embedded in an organic matrix. At least the quantum dots and the organic matrix are photoconductive semiconductors. The shell of each quantum dot is arranged as a tunneling barrier to require a charge carrier (an electron or a hole) at a base of the tunneling barrier in the organic matrix to perform quantum mechanical tunneling to reach the respective quantum dot. A first quantum state in each quantum dot is between a lowest unoccupied molecular orbital (LUMO) and a highest occupied molecular orbital (HOMO) of the organic matrix. Wave functions of the first quantum state of the plurality of quantum dots may overlap to form an intermediate band.

Agar/gelatin bilayer gel matrix fabricated by simple thermo-responsive sol-gel transition method.

Science.gov (United States)

Wang, Yifeng; Dong, Meng; Guo, Mengmeng; Wang, Xia; Zhou, Jing; Lei, Jian; Guo, Chuanhang; Qin, Chaoran

2017-08-01

We present a simple and environmentally-friendly method to generate an agar/gelatin bilayer gel matrix for further biomedical applications. In this method, the thermally responsive sol-gel transitions of agar and gelatin combined with the different transition temperatures are exquisitely employed to fabricate the agar/gelatin bilayer gel matrix and achieve separate loading for various materials (e.g., drugs, fluorescent materials, and nanoparticles). Importantly, the resulting bilayer gel matrix provides two different biopolymer environments (a polysaccharide environment vs a protein environment) with a well-defined border, which allows the loaded materials in different layers to retain their original properties (e.g., magnetism and fluorescence) and reduce mutual interference. In addition, the loaded materials in the bilayer gel matrix exhibit an interesting release behavior under the control of thermal stimuli. Consequently, the resulting agar/gelatin bilayer gel matrix is a promising candidate for biomedical applications in drug delivery, controlled release, fluorescence labeling, and bio-imaging. Copyright © 2017 Elsevier B.V. All rights reserved.

Effects and Correction of Closed Orbit Magnet Errors in the SNS Ring

Energy Technology Data Exchange (ETDEWEB)

Bunch, S.C.; Holmes, J.

2004-01-01

We consider the effect and correction of three types of orbit errors in SNS: quadrupole displacement errors, dipole displacement errors, and dipole field errors. Using the ORBIT beam dynamics code, we focus on orbit deflection of a standard pencil beam and on beam losses in a high intensity injection simulation. We study the correction of these orbit errors using the proposed system of 88 (44 horizontal and 44 vertical) ring beam position monitors (BPMs) and 52 (24 horizontal and 28 vertical) dipole corrector magnets. Correction is carried out numerically by adjusting the kick strengths of the dipole corrector magnets to minimize the sum of the squares of the BPM signals for the pencil beam. In addition to using the exact BPM signals as input to the correction algorithm, we also consider the effect of random BPM signal errors. For all three types of error and for perturbations of individual magnets, the correction algorithm always chooses the three-bump method to localize the orbit displacement to the region between the magnet and its adjacent correctors. The values of the BPM signals resulting from specified settings of the dipole corrector kick strengths can be used to set up the orbit response matrix, which can then be applied to the correction in the limit that the signals from the separate errors add linearly. When high intensity calculations are carried out to study beam losses, it is seen that the SNS orbit correction system, even with BPM uncertainties, is sufficient to correct losses to less than 10-4 in nearly all cases, even those for which uncorrected losses constitute a large portion of the beam.

A control method of the rotor re-levitation for different orbit responses during touchdowns in active magnetic bearings

Science.gov (United States)

Lyu, Mindong; Liu, Tao; Wang, Zixi; Yan, Shaoze; Jia, Xiaohong; Wang, Yuming

2018-05-01

Touchdown can make active magnetic bearings (AMB) unable to work, and bring severe damages to touchdown bearings (TDB). To resolve it, we presents a novel re-levitation method consisting of two operations, i.e., orbit response recognition and rotor re-levitation. In the operation of orbit response recognition, the three orbit responses (pendulum vibration, combined rub and bouncing, and full rub) can be identified by the expectation of radial displacement of rotor and expectation of instantaneous frequency (IF) of rotor motion in the sampling period. In the rotor re-levitation operation, a decentralized PID control algorithm is employed for pendulum vibration and combined rub and bouncing, and the decentralized PID control algorithm and another whirl damping algorithm, in which the weighting factor is determined by the whirl frequency, are jointly executed for the full rub. The method has been demonstrated by the simulation results of an AMB model. The results reveal that the method is effective in actively suppressing the whirl motion and promptly re-levitating the rotor. As the PID control algorithm and the simple operations of signal processing are employed, the algorithm has a low computation intensity, which makes it more easily realized in practical applications.

Corbit reference manual

International Nuclear Information System (INIS)

Evans, K. Jr.

1995-09-01

Corbit is a general-purpose, command-line program to implement orbit correction for the Advanced Photon Source. Its main purpose is to correct the orbit using a file containing the inverse of a response matrix and the names of the monitors and correctors. It will also: Calculate the response matrix from lattice data; calculate the singular value decomposition of the response matrix; remove singular values from the singular value decomposition; calculate the inverse from the singular value decomposition; use only a subset of the monitors or the correctors; preview the corrected orbit; match a desired orbit; calibrate the response matrix from excitation curve data for the correctors; apply an overall calibration to the response matrix; and compensate for the value of B*Rho

Asteroid orbital error analysis: Theory and application

Science.gov (United States)

Muinonen, K.; Bowell, Edward

1992-01-01

We present a rigorous Bayesian theory for asteroid orbital error estimation in which the probability density of the orbital elements is derived from the noise statistics of the observations. For Gaussian noise in a linearized approximation the probability density is also Gaussian, and the errors of the orbital elements at a given epoch are fully described by the covariance matrix. The law of error propagation can then be applied to calculate past and future positional uncertainty ellipsoids (Cappellari et al. 1976, Yeomans et al. 1987, Whipple et al. 1991). To our knowledge, this is the first time a Bayesian approach has been formulated for orbital element estimation. In contrast to the classical Fisherian school of statistics, the Bayesian school allows a priori information to be formally present in the final estimation. However, Bayesian estimation does give the same results as Fisherian estimation when no priori information is assumed (Lehtinen 1988, and reference therein).

Quadratically convergent algorithm for orbital optimization in the orbital-optimized coupled-cluster doubles method and in orbital-optimized second-order Møller-Plesset perturbation theory

Science.gov (United States)

Bozkaya, Uǧur; Turney, Justin M.; Yamaguchi, Yukio; Schaefer, Henry F.; Sherrill, C. David

2011-09-01

Using a Lagrangian-based approach, we present a more elegant derivation of the equations necessary for the variational optimization of the molecular orbitals (MOs) for the coupled-cluster doubles (CCD) method and second-order Møller-Plesset perturbation theory (MP2). These orbital-optimized theories are referred to as OO-CCD and OO-MP2 (or simply "OD" and "OMP2" for short), respectively. We also present an improved algorithm for orbital optimization in these methods. Explicit equations for response density matrices, the MO gradient, and the MO Hessian are reported both in spin-orbital and closed-shell spin-adapted forms. The Newton-Raphson algorithm is used for the optimization procedure using the MO gradient and Hessian. Further, orbital stability analyses are also carried out at correlated levels. The OD and OMP2 approaches are compared with the standard MP2, CCD, CCSD, and CCSD(T) methods. All these methods are applied to H2O, three diatomics, and the O_4^+ molecule. Results demonstrate that the CCSD and OD methods give nearly identical results for H2O and diatomics; however, in symmetry-breaking problems as exemplified by O_4^+, the OD method provides better results for vibrational frequencies. The OD method has further advantages over CCSD: its analytic gradients are easier to compute since there is no need to solve the coupled-perturbed equations for the orbital response, the computation of one-electron properties are easier because there is no response contribution to the particle density matrices, the variational optimized orbitals can be readily extended to allow inactive orbitals, it avoids spurious second-order poles in its response function, and its transition dipole moments are gauge invariant. The OMP2 has these same advantages over canonical MP2, making it promising for excited state properties via linear response theory. The quadratically convergent orbital-optimization procedure converges quickly for OMP2, and provides molecular properties that

Thermo- and pH-responsive polymer brushes-grafted gigaporous polystyrene microspheres as a high-speed protein chromatography matrix.

Science.gov (United States)

Qu, Jian-Bo; Xu, Yu-Liang; Liu, Jun-Yi; Zeng, Jing-Bin; Chen, Yan-Li; Zhou, Wei-Qing; Liu, Jian-Guo

2016-04-08

Dual thermo- and pH-responsive chromatography has been proposed using poly(N-isopropylacrylamide-co-butyl methacrylate-co-N,N-dimethylaminopropyl acrylamide) (P(NIPAM-co-BMA-co-DMAPAAM)) brushes grafted gigaporous polystyrene microspheres (GPM) as matrix. Atom transfer radical polymerization (ATRP) initiator was first coupled onto GPM through Friedel-Crafts acylation with 2-bromoisobutyryl bromide. The dual-responsive polymer brushes were then grafted onto GPM via surface-initiated ATRP. The surface composition, gigaporous structure, protein adsorption and dual-responsive chromatographic properties of the matrix (GPM-P(NIPAM-co-BMA-co-DMAPAAM) were characterized in detail. Results showed that GPM were successfully grafted with thermoresponsive cationic polymer brushes and that the gigaporous structure was well maintained. A column packed with GPM-P(NIPAM-co-BMA-co-DMAPAAM presented low backpressure, good permeability and appreciable thermo-responsibility. By changing pH of the mobile phase and temperature of the column in turn, the column can separate three model proteins at the mobile phase velocity up to 2528cmh(-1). A separation mechanism of this matrix was also proposed. All results indicate that the dual thermo- and pH-responsive chromatography matrix has great potentials in 'green' high-speed protein chromatography. Copyright © 2016 Elsevier B.V. All rights reserved.

An identification method of orbit responses rooting in vibration analysis of rotor during touchdowns of active magnetic bearings

Science.gov (United States)

Liu, Tao; Lyu, Mindong; Wang, Zixi; Yan, Shaoze

2018-02-01

Identification of orbit responses can make the active protection operation more easily realize for active magnetic bearings (AMB) in case of touchdowns. This paper presents an identification method of the orbit responses rooting on signal processing of rotor displacements during touchdowns. The recognition method consists of two major steps. Firstly, the combined rub and bouncing is distinguished from the other orbit responses by the mathematical expectation of axis displacements of the rotor. Because when the combined rub and bouncing occurs, the rotor of AMB will not be always close to the touchdown bearings (TDB). Secondly, we recognize the pendulum vibration and the full rub by the Fourier spectrum of displacement in horizontal direction, as the frequency characteristics of the two responses are different. The principle of the whole identification algorithm is illustrated by two sets of signal generated by a dynamic model of the specific rotor-TDB system. The universality of the method is validated by other four sets of signal. Besides, the adaptability of noise is also tested by adding white noises with different strengths, and the result is promising. As the mathematical expectation and Discrete Fourier transform are major calculations of the algorithm, the calculation quantity of the algorithm is low, so it is fast, easily realized and embedded in the AMB controller, which has an important engineering value for the protection of AMBs during touchdowns.

Plasticity of the actin cytoskeleton in response to extracellular matrix nanostructure and dimensionality

NARCIS (Netherlands)

Starke, J.; Wehrle-Haller, B.; Friedl, P.

2014-01-01

Mobile cells discriminate and adapt to mechanosensory input from extracellular matrix (ECM) topographies to undergo actin-based polarization, shape change and migration. We tested 'cell-intrinsic' and adaptive components of actin-based cell migration in response to widely used in vitro

Nuclear Matrix Elements for the $\\beta\\beta$ Decay of the $^{76}$Ge

CERN Document Server

Brown, B A; Horoi, M

2015-01-01

The nuclear matrix elements for two-neutrino double-beta (2 n$\\beta\\beta$ ) and zero-neutrino double-beta (0 n$\\beta\\beta$) decay of 76 Ge are evaluated in terms of the configuration interaction (CI), quasiparticle random phase approximation (QRPA) and interacting boson model (IBM) methods. We show that the decomposition of the matrix elements in terms of interemediate states in 74 Ge is dominated by ground state of this nucleus. We consider corrections to the CI results that arise from configurations admixtures involving orbitals out-side of the CI configuration space by using results from QRPA, many-body-perturbation theory, and the connections to related observables. The CI two-neutrino matrix element is reduced due to the inclusion of spin-orbit partners, and to many-body correlations connected with Gamow-Teller beta decay. The CI zero-neutrino matrix element for the heavy neutrino is enhanced due to particle-particle correlations that are connected with the odd-even oscillations in the nuclear masse...

Comparison of Damage Models for Predicting the Non-Linear Response of Laminates Under Matrix Dominated Loading Conditions

Science.gov (United States)

Schuecker, Clara; Davila, Carlos G.; Rose, Cheryl A.

2010-01-01

Five models for matrix damage in fiber reinforced laminates are evaluated for matrix-dominated loading conditions under plane stress and are compared both qualitatively and quantitatively. The emphasis of this study is on a comparison of the response of embedded plies subjected to a homogeneous stress state. Three of the models are specifically designed for modeling the non-linear response due to distributed matrix cracking under homogeneous loading, and also account for non-linear (shear) behavior prior to the onset of cracking. The remaining two models are localized damage models intended for predicting local failure at stress concentrations. The modeling approaches of distributed vs. localized cracking as well as the different formulations of damage initiation and damage progression are compared and discussed.

Response matrix method and its application to SCWR single channel stability analysis

International Nuclear Information System (INIS)

Zhao, Jiyun; Tseng, K.J.; Tso, C.P.

2011-01-01

To simulate the reactor system dynamic features during density wave oscillations (DWO), both the non-linear method and the linear method can be used. Although some transient information is lost through model linearization, the high computational efficiency and relatively accurate results make the linear analysis methodology attractive, especially for prediction of the onset of instability. In the linear stability analysis, the system models are simplified through linearization of the complex non-linear differential equations, and then, the linear differential equations are generally solved in the frequency domain through Laplace transformation. In this paper, a system response matrix method was introduced by directly solving the differential equations in the time domain. By using a system response matrix method, the complicated transfer function derivation, which must be done in the frequency domain method, can be avoided. Using the response matrix method, a model was developed and applied to the single channel or parallel channel type instability analyses of the typical proposed SCWR design. The sensitivity of the decay ratio (DR) to the axial mesh size was analyzed and it was found that the DR is not sensitive to mesh size once sufficient number of axial nodes is applied. To demonstrate the effects of the inlet orificing to the stability feature for the supercritical condition, the sensitivity of the stability to inlet orifice coefficient was conducted for hot channel. It is clearly shown that a higher inlet orifice coefficient will make the system more stable. The susceptibility of stability to operating parameters such as mass flow rate, power and system pressure was also performed. And the measure to improve the SCWR stability sensitivity to operating parameters was investigated. It was found that the SCWR stability sensitivity feature can be improved by carefully managing the inlet orifices and choosing proper operating parameters. (author)

Cytoskeletal remodeling of connective tissue fibroblasts in response to static stretch is dependent on matrix material properties

Science.gov (United States)

Abbott, Rosalyn D; Koptiuch, Cathryn; Iatridis, James C; Howe, Alan K; Badger, Gary J; Langevin, Helene M

2012-01-01

In areolar “loose” connective tissue, fibroblasts remodel their cytoskeleton within minutes in response to static stretch resulting in increased cell body cross-sectional area that relaxes the tissue to a lower state of resting tension. It remains unknown whether the loosely arranged collagen matrix, characteristic of areolar connective tissue, is required for this cytoskeletal response to occur. The purpose of this study was to evaluate cytoskeletal remodeling of fibroblasts in and dissociated from areolar and dense connective tissue in response to 2 hours of static stretch in both native tissue and collagen gels of varying crosslinking. Rheometric testing indicated that the areolar connective tissue had a lower dynamic modulus and was more viscous than the dense connective tissue. In response to stretch, cells within the more compliant areolar connective tissue adopted a large “sheet-like” morphology that was in contrast to the smaller dendritic morphology in the dense connective tissue. By adjusting the in vitro collagen crosslinking, and the resulting dynamic modulus, it was demonstrated that cells dissociated from dense connective tissue are capable of responding when seeded into a compliant matrix, while cells dissociated from areolar connective tissue can lose their ability to respond when their matrix becomes stiffer. This set of experiments indicated stretch-induced fibroblast expansion was dependent on the distinct matrix material properties of areolar connective tissues as opposed to the cells’ tissue of origin. These results also suggest that disease and pathological processes with increased crosslinks, such as diabetes and fibrosis, could impair fibroblast responsiveness in connective tissues. PMID:22552950

Solving eigenvalue response matrix equations with nonlinear techniques

International Nuclear Information System (INIS)

Roberts, Jeremy A.; Forget, Benoit

2014-01-01

Highlights: • High performance solvers were applied within ERMM for the first time. • Accelerated fixed-point methods were developed that reduce computational times by 2–3. • A nonlinear, Newton-based ERMM led to similar improvement and more robustness. • A 3-D, SN-based ERMM shows how ERMM can apply fine-mesh methods to full-core analysis. - Abstract: This paper presents new algorithms for use in the eigenvalue response matrix method (ERMM) for reactor eigenvalue problems. ERMM spatially decomposes a domain into independent nodes linked via boundary conditions approximated as truncated orthogonal expansions, the coefficients of which are response functions. In its simplest form, ERMM consists of a two-level eigenproblem: an outer Picard iteration updates the k-eigenvalue via balance, while the inner λ-eigenproblem imposes neutron balance between nodes. Efficient methods are developed for solving the inner λ-eigenvalue problem within the outer Picard iteration. Based on results from several diffusion and transport benchmark models, it was found that the Krylov–Schur method applied to the λ-eigenvalue problem reduces Picard solver times (excluding response generation) by a factor of 2–5. Furthermore, alternative methods, including Picard acceleration schemes, Steffensen’s method, and Newton’s method, are developed in this paper. These approaches often yield faster k-convergence and a need for fewer k-dependent response function evaluations, which is important because response generation is often the primary cost for problems using responses computed online (i.e., not from a precomputed database). Accelerated Picard iteration was found to reduce total computational times by 2–3 compared to the unaccelerated case for problems dominated by response generation. In addition, Newton’s method was found to provide nearly the same performance with improved robustness

Quark Orbital Angular Momentum

Directory of Open Access Journals (Sweden)

Burkardt Matthias

2015-01-01

Full Text Available Definitions of orbital angular momentum based on Wigner distributions are used as a framework to discuss the connection between the Ji definition of the quark orbital angular momentum and that of Jaffe and Manohar. We find that the difference between these two definitions can be interpreted as the change in the quark orbital angular momentum as it leaves the target in a DIS experiment. The mechanism responsible for that change is similar to the mechanism that causes transverse single-spin asymmetries in semi-inclusive deep-inelastic scattering.

EXPERIMENTAL DESIGN AND RESPONSE SURFACE MODELING OF PI/PES-ZEOLITE 4A MIXED MATRIX MEMBRANE FOR CO2 SEPARATION

Directory of Open Access Journals (Sweden)

T. D. KUSWORO

2015-09-01

Full Text Available This paper investigates the effect of preparation of polyimide/polyethersulfone (PI/PES blending-zeolite mixed matrix membrane through the manipulation of membrane production variables such as polymer concentration, blending composition and zeolite loading. Combination of central composite design and response surface methodology were applied to determine the main effect and interaction effects of these variables on membrane separation performance. The quadratic models between each response and the independent parameters were developed and the response surface models were tested with analysis of variance (ANOVA. In this study, PI/ (PES–zeolite 4A mixed matrix membranes were casted using dry/wet phase inversion technique. The separation performance of mixed matrix membrane had been tested using pure gases such as CO2 and CH4. The results showed that zeolite loading was the most significant variable that influenced the CO2/CH4 selectivity among three variables and the experimental results were in good agreement with those predicted by the proposed regression models. The gas separation performance of the membrane was relatively higher as compare to polymeric membrane. Therefore, combination of central composite design and response surface methodology can be used to prepare optimal condition for mixed matrix membrane fabrication. The incorporation of 20 wt% zeolite 4A into 25 wt% of PI/PES matrix had resulted in a high separation performance of membrane material.

Neural networks and orbit control in accelerators

International Nuclear Information System (INIS)

Bozoki, E.; Friedman, A.

1994-01-01

An overview of the architecture, workings and training of Neural Networks is given. We stress the aspects which are important for the use of Neural Networks for orbit control in accelerators and storage rings, especially its ability to cope with the nonlinear behavior of the orbit response to 'kicks' and the slow drift in the orbit response during long-term operation. Results obtained for the two NSLS storage rings with several network architectures and various training methods for each architecture are given

On the observability of the quark orbital angular momentum distribution

Energy Technology Data Exchange (ETDEWEB)

Courtoy, Aurore, E-mail: aurore.courtoy@ulg.be [IFPA, AGO Department, Université de Liège, Bât. B5, Sart Tilman, B-4000 Liège (Belgium); Laboratori Nazionali di Frascati, INFN, Frascati (Italy); Goldstein, Gary R., E-mail: gary.goldstein@tufts.edu [Department of Physics and Astronomy, Tufts University, Medford, MA 02155 (United States); Osvaldo Gonzalez Hernandez, J., E-mail: jog4m@virginia.edu [Istituto Nazionale di Fisica Nucleare (INFN) – Sezione di Torino, via P. Giuria, 1, 10125 Torino (Italy); Liuti, Simonetta, E-mail: sl4y@virginia.edu [University of Virginia – Physics Department, 382 McCormick Rd., Charlottesville, VA 22904 (United States); Laboratori Nazionali di Frascati, INFN, Frascati (Italy); Rajan, Abha, E-mail: ar5xc@virginia.edu [University of Virginia – Physics Department, 382 McCormick Rd., Charlottesville, VA 22904 (United States)

2014-04-04

We argue that due to parity constraints, the helicity combination of the purely momentum space counterparts of the Wigner distributions – the generalized transverse momentum distributions – that describes the configuration of an unpolarized quark in a longitudinally polarized nucleon can enter the deeply virtual Compton scattering amplitude only through matrix elements involving a final state interaction. The relevant matrix elements in turn involve light-cone operators projections in the transverse direction, or they appear in the deeply virtual Compton scattering amplitude at twist three. Orbital angular momentum or the spin structure of the nucleon was a major reason for these various distributions and amplitudes to have been introduced. We show that the twist three contributions associated with orbital angular momentum are related to the target-spin asymmetry in deeply virtual Compton scattering, already measured at HERMES.

Thermomechanical response of a cross-ply titanium matrix composite subjected to a generic hypersonic flight profile

International Nuclear Information System (INIS)

Mirdamadi, M.; Johnson, W.S.

1993-01-01

Cross-ply laminate behavior of Ti-15V-3Cr-3AI-3Sn (Ti-15-3) matrix reinforced with continuous silicon-carbide fibers (SCS-6) subjected to a generic hypersonic flight profile was evaluated experimentally and analytically. Thermomechanical fatigue test techniques were developed to conduct a simulation of a generic hypersonic flight profile. A micromechanical analysis was used. The analysis predicts the stress-strain response of the laminate and of the constituents in each ply during thermal and mechanical cycling by using only constituent properties as input. The fiber was modeled as elastic with transverse orthotropic and temperature-dependent properties. The matrix was modeled using a thermoviscoplastic constitutive relation. The fiber transverse modulus was reduced in the analysis to simulate the fiber-matrix interface failure. Excellent correlation was found between measured and predicted laminate stress-strain response due to generic hypersonic flight profile when fiber debonding was modeled

Orbital-motion-limited theory of dust charging and plasma response

International Nuclear Information System (INIS)

Tang, Xian-Zhu; Luca Delzanno, Gian

2014-01-01

The foundational theory for dusty plasmas is the dust charging theory that provides the dust potential and charge arising from the dust interaction with a plasma. The most widely used dust charging theory for negatively charged dust particles is the so-called orbital motion limited (OML) theory, which predicts the dust potential and heat collection accurately for a variety of applications, but was previously found to be incapable of evaluating the dust charge and plasma response in any situation. Here, we report a revised OML formulation that is able to predict the plasma response and hence the dust charge. Numerical solutions of the new OML model show that the widely used Whipple approximation of dust charge-potential relationship agrees with OML theory in the limit of small dust radius compared with plasma Debye length, but incurs large (order-unity) deviation from the OML prediction when the dust size becomes comparable with or larger than plasma Debye length. This latter case is expected for the important application of dust particles in a tokamak plasma

Spin-inversion in nanoscale graphene sheets with a Rashba spin-orbit barrier

Directory of Open Access Journals (Sweden)

Somaieh Ahmadi

2012-03-01

Full Text Available Spin-inversion properties of an electron in nanoscale graphene sheets with a Rashba spin-orbit barrier is studied using transfer matrix method. It is found that for proper values of Rashba spin-orbit strength, perfect spin-inversion can occur in a wide range of electron incident angle near the normal incident. In this case, the graphene sheet with Rashba spin-orbit barrier can be considered as an electron spin-inverter. The efficiency of spin-inverter can increase up to a very high value by increasing the length of Rashba spin-orbit barrier. The effect of intrinsic spin-orbit interaction on electron spin inversion is then studied. It is shown that the efficiency of spin-inverter decreases slightly in the presence of intrinsic spin-orbit interaction. The present study can be used to design graphene-based spintronic devices.

Massively parallel performance of neutron transport response matrix algorithms

International Nuclear Information System (INIS)

Hanebutte, U.R.; Lewis, E.E.

1993-01-01

Massively parallel red/black response matrix algorithms for the solution of within-group neutron transport problems are implemented on the Connection Machines-2, 200 and 5. The response matrices are dericed from the diamond-differences and linear-linear nodal discrete ordinate and variational nodal P 3 approximations. The unaccelerated performance of the iterative procedure is examined relative to the maximum rated performances of the machines. The effects of processor partitions size, of virtual processor ratio and of problems size are examined in detail. For the red/black algorithm, the ratio of inter-node communication to computing times is found to be quite small, normally of the order of ten percent or less. Performance increases with problems size and with virtual processor ratio, within the memeory per physical processor limitation. Algorithm adaptation to courser grain machines is straight-forward, with total computing time being virtually inversely proportional to the number of physical processors. (orig.)

Targeting Ballistic Lunar Capture Trajectories Using Periodic Orbits in the Sun-Earth CRTBP

Science.gov (United States)

Cooley, D.S.; Griesemer, Paul Ricord; Ocampo, Cesar

2009-01-01

A particular periodic orbit in the Earth-Sun circular restricted three body problem is shown to have the characteristics needed for a ballistic lunar capture transfer. An injection from a circular parking orbit into the periodic orbit serves as an initial guess for a targeting algorithm. By targeting appropriate parameters incrementally in increasingly complicated force models and using precise derivatives calculated from the state transition matrix, a reliable algorithm is produced. Ballistic lunar capture trajectories in restricted four body systems are shown to be able to be produced in a systematic way.

Measuring multi-configurational character by orbital entanglement

Science.gov (United States)

Stein, Christopher J.; Reiher, Markus

2017-09-01

One of the most critical tasks at the very beginning of a quantum chemical investigation is the choice of either a multi- or single-configurational method. Naturally, many proposals exist to define a suitable diagnostic of the multi-configurational character for various types of wave functions in order to assist this crucial decision. Here, we present a new orbital-entanglement-based multi-configurational diagnostic termed Zs(1). The correspondence of orbital entanglement and static (or non-dynamic) electron correlation permits the definition of such a diagnostic. We chose our diagnostic to meet important requirements such as well-defined limits for pure single-configurational and multi-configurational wave functions. The Zs(1) diagnostic can be evaluated from a partially converged, but qualitatively correct, and therefore inexpensive density matrix renormalisation group wave function as in our recently presented automated active orbital selection protocol. Its robustness and the fact that it can be evaluated at low cost make this diagnostic a practical tool for routine applications.

Theory and design methods of special space orbits

CERN Document Server

Zhang, Yasheng; Zhou, Haijun

2017-01-01

This book focuses on the theory and design of special space orbits. Offering a systematic and detailed introduction to the hovering orbit, spiral cruising orbit, multi-target rendezvous orbit, initiative approaching orbit, responsive orbit and earth pole-sitter orbit, it also discusses the concept, theory, design methods and application of special space orbits, particularly the design and control method based on kinematics and astrodynamics. In addition the book presents the latest research and its application in space missions. It is intended for researchers, engineers and postgraduates, especially those working in the fields of orbit design and control, as well as space-mission planning and research.

Production of matrix metalloproteinases in response to mycobacterial infection.

Science.gov (United States)

Quiding-Järbrink, M; Smith, D A; Bancroft, G J

2001-09-01

Matrix metalloproteinases (MMPs) constitute a large family of enzymes with specificity for the various proteins of the extracellular matrix which are implicated in tissue remodeling processes and chronic inflammatory conditions. To investigate the role of MMPs in immunity to mycobacterial infections, we incubated murine peritoneal macrophages with viable Mycobacterium bovis BCG or Mycobacterium tuberculosis H37Rv and assayed MMP activity in the supernatants by zymography. Resting macrophages secreted only small amounts of MMP-9 (gelatinase B), but secretion increased dramatically in a dose-dependent manner in response to either BCG or M. tuberculosis in vitro. Incubation with mycobacteria also induced increased MMP-2 (gelatinase A) activity. Neutralization of tumor necrosis alpha (TNF-alpha), and to a lesser extent interleukin 18 (IL-18), substantially reduced MMP production in response to mycobacteria. Exogenous addition of TNF-alpha or IL-18 induced macrophages to express MMPs, even in the absence of bacteria. The immunoregulatory cytokines gamma interferon (IFN-gamma), IL-4, and IL-10 all suppressed BCG-induced MMP production, but through different mechanisms. IFN-gamma treatment increased macrophage secretion of TNF-alpha but still reduced their MMP activity. Conversely, IL-4 and IL-10 seemed to act by reducing the amount of TNF-alpha available to the macrophages. Finally, infection of BALB/c or severe combined immunodeficiency (SCID) mice with either BCG or M. tuberculosis induced substantial increases in MMP-9 activity in infected tissues. In conclusion, we show that mycobacterial infection induces MMP-9 activity both in vitro and in vivo and that this is regulated by TNF-alpha, IL-18, and IFN-gamma. These findings indicate a possible contribution of MMPs to tissue remodeling processes that occur in mycobacterial infections.

Decomposition of continuum {gamma}-ray spectra using synthesized response matrix

Energy Technology Data Exchange (ETDEWEB)

Jandel, M.; Morhac, M.; Kliman, J.; Krupa, L.; Matousek, V. E-mail: vladislav.matousek@savba.sk; Hamilton, J.H.; Ramayya, A.V

2004-01-01

The efficient methods of decomposition of {gamma}-ray spectra, based on the Gold algorithm, are presented. They use a response matrix of Gammasphere, which was obtained by synthesis of simulated and interpolated response functions using a new developed interpolation algorithm. The decomposition method has been applied to the measured spectra of {sup 152}Eu and {sup 56}Co. The results show a very effective removal of the background counts and their concentration into the corresponding photopeaks. The peak-to-total ratio in the spectra achieved after applying the decomposition method is in the interval 0.95-0.99. In addition, a new advanced algorithm of the 'boosted' decomposition has been proposed. In the spectra obtained after applying the boosted decomposition to the measured spectra, very narrow photopeaks are observed with the counts concentrated to several channels.

Importance of matrix inelastic deformations in the initial response of magnetic elastomers.

Science.gov (United States)

Sánchez, Pedro A; Gundermann, Thomas; Dobroserdova, Alla; Kantorovich, Sofia S; Odenbach, Stefan

2018-03-14

Being able to predict and understand the behaviour of soft magnetic materials paves the way to their technological applications. In this study we analyse the magnetic response of soft magnetic elastomers (SMEs) with magnetically hard particles. We present experimental evidence of a difference between the first and next magnetisation loops exhibited by these SMEs, which depends non-monotonically on the interplay between the rigidity of the polymer matrix, its mechanical coupling with the particles, and the magnetic interactions in the system. In order to explain the microstructural mechanism behind this behaviour, we used a minimal computer simulation model whose results evidence the importance of irreversible matrix deformations due to both translations and rotations of the particles. To confirm the simulation findings, computed tomography (CT) was used. We conclude that the initial exposure to the field triggers the inelastic matrix relaxation in the SMEs, as particles attempt to reorient. However, once the necessary degree of freedom is achieved, both the rotations and the magnetisation behaviour become stationary. We expect this scenario not only to be limited to the materials studied here, but also to apply to a broader class of hybrid SMEs.

A stromal cell-derived factor-1 releasing matrix enhances the progenitor cell response and blood vessel growth in ischaemic skeletal muscle

Directory of Open Access Journals (Sweden)

D Kuraitis

2011-09-01

Full Text Available Although many regenerative cell therapies are being developed to replace or regenerate ischaemic muscle, the lack of vasculature and poor persistence of the therapeutic cells represent major limiting factors to successful tissue restoration. In response to ischaemia, stromal cell-derived factor-1 (SDF-1 is up-regulated by the affected tissue to stimulate stem cell-mediated regenerative responses. Therefore, we encapsulated SDF-1 into alginate microspheres and further incorporated these into an injectable collagen-based matrix in order to improve local delivery. Microsphere-matrix impregnation reduced the time for matrix thermogelation, and also increased the viscosity reached. This double-incorporation prolonged the release of SDF-1, which maintained adhesive and migratory bioactivity, attributed to chemotaxis in response to SDF-1. In vivo, treatment of ischaemic hindlimb muscle with microsphere-matrix led to increased mobilisation of bone marrow-derived progenitor cells, and also improved recruitment of angiogenic cells expressing the SDF-1 receptor (CXCR4 from bone marrow and local tissues. Both matrix and SDF-1-releasing matrix were successful at restoring perfusion, but SDF-1 treatment appeared to play an earlier role, as evidenced by arterioles that are phenotypically older and by increased angiogenic cytokine production, stimulating the generation of a qualitative microenvironment for a rapid and therefore more efficient regeneration. These results support the release of implanted SDF-1 as a promising method for enhancing progenitor cell responses and restoring perfusion to ischaemic tissues via neovascularisation.

Variational Optimization of the Second-Order Density Matrix Corresponding to a Seniority-Zero Configuration Interaction Wave Function.

Science.gov (United States)

Poelmans, Ward; Van Raemdonck, Mario; Verstichel, Brecht; De Baerdemacker, Stijn; Torre, Alicia; Lain, Luis; Massaccesi, Gustavo E; Alcoba, Diego R; Bultinck, Patrick; Van Neck, Dimitri

2015-09-08

We perform a direct variational determination of the second-order (two-particle) density matrix corresponding to a many-electron system, under a restricted set of the two-index N-representability P-, Q-, and G-conditions. In addition, we impose a set of necessary constraints that the two-particle density matrix must be derivable from a doubly occupied many-electron wave function, i.e., a singlet wave function for which the Slater determinant decomposition only contains determinants in which spatial orbitals are doubly occupied. We rederive the two-index N-representability conditions first found by Weinhold and Wilson and apply them to various benchmark systems (linear hydrogen chains, He, N2, and CN(-)). This work is motivated by the fact that a doubly occupied many-electron wave function captures in many cases the bulk of the static correlation. Compared to the general case, the structure of doubly occupied two-particle density matrices causes the associate semidefinite program to have a very favorable scaling as L(3), where L is the number of spatial orbitals. Since the doubly occupied Hilbert space depends on the choice of the orbitals, variational calculation steps of the two-particle density matrix are interspersed with orbital-optimization steps (based on Jacobi rotations in the space of the spatial orbitals). We also point to the importance of symmetry breaking of the orbitals when performing calculations in a doubly occupied framework.

Engineering a collagen matrix that replicates the biological properties of native extracellular matrix.

Science.gov (United States)

Nam, Kwangwoo; Sakai, Yuuki; Funamoto, Seiichi; Kimura, Tsuyoshi; Kishida, Akio

2011-01-01

In this study, we aimed to replicate the function of native tissues that can be used in tissue engineering and regenerative medicine. The key to such replication is the preparation of an artificial collagen matrix that possesses a structure resembling that of the extracellular matrix. We, therefore, prepared a collagen matrix by fibrillogenesis in a NaCl/Na(2)HPO(4) aqueous solution using a dialysis cassette and investigated its biological behavior in vitro and in vivo. The in vitro cell adhesion and proliferation did not show any significant differences. The degradation rate in the living body could be controlled according to the preparation condition, where the collagen matrix with high water content (F-collagen matrix, >98%) showed fast degradation and collagen matrix with lower water content (T-collagen matrix, >80%) showed no degradation for 8 weeks. The degradation did not affect the inflammatory response at all and relatively faster wound healing response was observed. Comparing this result with that of collagen gel and decellularized cornea, it can be concluded that the structural factor is very important and no cell abnormal behavior would be observed for quaternary structured collagen matrix.

A real-space stochastic density matrix approach for density functional electronic structure.

Science.gov (United States)

Beck, Thomas L

2015-12-21

The recent development of real-space grid methods has led to more efficient, accurate, and adaptable approaches for large-scale electrostatics and density functional electronic structure modeling. With the incorporation of multiscale techniques, linear-scaling real-space solvers are possible for density functional problems if localized orbitals are used to represent the Kohn-Sham energy functional. These methods still suffer from high computational and storage overheads, however, due to extensive matrix operations related to the underlying wave function grid representation. In this paper, an alternative stochastic method is outlined that aims to solve directly for the one-electron density matrix in real space. In order to illustrate aspects of the method, model calculations are performed for simple one-dimensional problems that display some features of the more general problem, such as spatial nodes in the density matrix. This orbital-free approach may prove helpful considering a future involving increasingly parallel computing architectures. Its primary advantage is the near-locality of the random walks, allowing for simultaneous updates of the density matrix in different regions of space partitioned across the processors. In addition, it allows for testing and enforcement of the particle number and idempotency constraints through stabilization of a Feynman-Kac functional integral as opposed to the extensive matrix operations in traditional approaches.

Gradient-based stochastic estimation of the density matrix

Science.gov (United States)

Wang, Zhentao; Chern, Gia-Wei; Batista, Cristian D.; Barros, Kipton

2018-03-01

Fast estimation of the single-particle density matrix is key to many applications in quantum chemistry and condensed matter physics. The best numerical methods leverage the fact that the density matrix elements f(H)ij decay rapidly with distance rij between orbitals. This decay is usually exponential. However, for the special case of metals at zero temperature, algebraic decay of the density matrix appears and poses a significant numerical challenge. We introduce a gradient-based probing method to estimate all local density matrix elements at a computational cost that scales linearly with system size. For zero-temperature metals, the stochastic error scales like S-(d+2)/2d, where d is the dimension and S is a prefactor to the computational cost. The convergence becomes exponential if the system is at finite temperature or is insulating.

Thermal response of an aeroassisted orbital-transfer vehicle with a conical drag brake

Science.gov (United States)

Pitts, W. C.; Murbach, M. S.

1984-01-01

As an aeroassisted orbital-transfer vehicle (AOTV) goes through an aerobraking maneuver, a significant amount of heat is generated. In this paper, the thermal response of a specific AOTV to this aerobrake heating is examined. The vehicle has a 70 deg, conical drag-brake heat shield attached to a cylindrical body which contains the payload. The heat shield is made of silica fabric. The heat-shield thickness is varied from that of a thin cloth to a 1.5-cm blanket. The fabric thickness, the radiation absorptivity of the vehicle surface materials, and radiation from the wake are all significant parameters in the thermal response to the heating produced by the braking maneuver. The maximum temperatures occur in the vicinity of the interface between the body and the conical heat shield.

Thermal Response of an Aeroassisted Orbital Transfer Vehicle with a Conical Drag Brake

Science.gov (United States)

Pitts, W. C.; Murbach, M. S.

1985-01-01

As an aeroassisted orbital transfer vehicle (AOTV) goes through an aerobraking maneuver a significant amount of heat is generated. In this paper, the thermal response of a specific AOTV to this aerobrake heating is examined. The vehicle has a 70-deg, Conical drag-brake heat shield attached to a cylindrical body which contains the payload. The heat shield is made of ceramic fabric its thickness is varied from that of a thin cloth to a 1.5-cm blanket. The fabric thickness, the radiation absorptivity of the vehicle surface materials, and radiation from the wake are all significant parameters in the thermal response to the heating produced by the braking maneuver. The maximum temperatures occur In the vicinity of the interface between the body and the conical heat shield.

Linear Magnetoelectric Effect by Orbital Magnetism

NARCIS (Netherlands)

Scaramucci, A.; Bousquet, E.; Fechner, M.; Mostovoy, M.; Spaldin, N. A.

2012-01-01

We use symmetry analysis and first-principles calculations to show that the linear magnetoelectric effect can originate from the response of orbital magnetic moments to the polar distortions induced by an applied electric field. Using LiFePO4 as a model compound we show that spin-orbit coupling

Closed orbit related problems: Correction, feedback, and analysis

International Nuclear Information System (INIS)

Bozoki, E.S.

1995-01-01

Orbit correction - moving the orbit to a desired orbit, orbit stability - keeping the orbit on the desired orbit using feedback to filter out unwanted noise, and orbit analysis - to learn more about the model of the machine, are strongly interrelated. They are the three facets of the same problem. The better one knows the model of the machine, the better the predictions that can be made on the behavior of the machine (inverse modeling) and the more accurately one can control the machine. On the other hand, one of the tools to learn more about the machine (modeling) is to study and analyze the orbit response to open-quotes kicks.close quotes

A case report of orbital Langerhans cell histiocytosis presenting as a orbital cellulitis.

Science.gov (United States)

Albert-Fort, M; González-Candial, M

2018-04-08

A 10-year-old girl was seen with a 3-week history of right upper lid swelling and with no other symptoms or fever. There was no recent history of sinusitis, trauma, or previous infection involving the periorbital area, or response to oral antibiotic treatment. Orbital computed tomography showed a lesion involving the upper margin of the orbit, and bone destruction at the orbital roof. Biopsy performed revealed the presence of Langerhans cell Histiocytosis. The lesion was surgically debulked and corticosteroids were used intra-operatively. The lesion responded to treatment. The orbital involvement of Langerhans cell histiocytosis, despite its low incidence, should be considered in the examination of acute peri-orbital swelling. It usually presents as an osteolytic lesion, and it is confirmed with a histological examination and immunohistochemical techniques for CD1a and S100. An interdisciplinary approach is recommended to rule out multifocal or multisystemic diseases, as well as to develop an appropriate treatment strategy. Copyright © 2018 Sociedad Española de Oftalmología. Publicado por Elsevier España, S.L.U. All rights reserved.

Shock Wave Response of Iron-based In Situ Metallic Glass Matrix Composites.

Science.gov (United States)

Khanolkar, Gauri R; Rauls, Michael B; Kelly, James P; Graeve, Olivia A; Hodge, Andrea M; Eliasson, Veronica

2016-03-02

The response of amorphous steels to shock wave compression has been explored for the first time. Further, the effect of partial devitrification on the shock response of bulk metallic glasses is examined by conducting experiments on two iron-based in situ metallic glass matrix composites, containing varying amounts of crystalline precipitates, both with initial composition Fe49.7Cr17.7Mn1.9Mo7.4W1.6B15.2C3.8Si2.4. The samples, designated SAM2X5-600 and SAM2X5-630, are X-ray amorphous and partially crystalline, respectively, due to differences in sintering parameters during sample preparation. Shock response is determined by making velocity measurements using interferometry techniques at the rear free surface of the samples, which have been subjected to impact from a high-velocity projectile launched from a powder gun. Experiments have yielded results indicating a Hugoniot Elastic Limit (HEL) to be 8.58 ± 0.53 GPa for SAM2X5-600 and 11.76 ± 1.26 GPa for SAM2X5-630. The latter HEL result is higher than elastic limits for any BMG reported in the literature thus far. SAM2X5-600 catastrophically loses post-yield strength whereas SAM2X5-630, while showing some strain-softening, retains strength beyond the HEL. The presence of crystallinity within the amorphous matrix is thus seen to significantly aid in strengthening the material as well as preserving material strength beyond yielding.

The human metapneumovirus matrix protein stimulates the inflammatory immune response in vitro.

Directory of Open Access Journals (Sweden)

Audrey Bagnaud-Baule

Full Text Available Each year, during winter months, human Metapneumovirus (hMPV is associated with epidemics of bronchiolitis resulting in the hospitalization of many infants. Bronchiolitis is an acute illness of the lower respiratory tract with a consequent inflammation of the bronchioles. The rapid onset of inflammation suggests the innate immune response may have a role to play in the pathogenesis of this hMPV infection. Since, the matrix protein is one of the most abundant proteins in the Paramyxoviridae family virion, we hypothesized that the inflammatory modulation observed in hMPV infected patients may be partly associated with the matrix protein (M-hMPV response. By western blot analysis, we detected a soluble form of M-hMPV released from hMPV infected cell as well as from M-hMPV transfected HEK 293T cells suggesting that M-hMPV may be directly in contact with antigen presenting cells (APCs during the course of infection. Moreover, flow cytometry and confocal microscopy allowed determining that M-hMPV was taken up by dendritic cells (moDCs and macrophages inducing their activation. Furthermore, these moDCs enter into a maturation process inducing the secretion of a broad range of inflammatory cytokines when exposed to M-hMPV. Additionally, M-hMPV activated DCs were shown to stimulate IL-2 and IFN-γ production by allogeneic T lymphocytes. This M-hMPV-mediated activation and antigen presentation of APCs may in part explain the marked inflammatory immune response observed in pathology induced by hMPV in patients.

Multireference quantum chemistry through a joint density matrix renormalization group and canonical transformation theory.

Science.gov (United States)

Yanai, Takeshi; Kurashige, Yuki; Neuscamman, Eric; Chan, Garnet Kin-Lic

2010-01-14

We describe the joint application of the density matrix renormalization group and canonical transformation theory to multireference quantum chemistry. The density matrix renormalization group provides the ability to describe static correlation in large active spaces, while the canonical transformation theory provides a high-order description of the dynamic correlation effects. We demonstrate the joint theory in two benchmark systems designed to test the dynamic and static correlation capabilities of the methods, namely, (i) total correlation energies in long polyenes and (ii) the isomerization curve of the [Cu(2)O(2)](2+) core. The largest complete active spaces and atomic orbital basis sets treated by the joint DMRG-CT theory in these systems correspond to a (24e,24o) active space and 268 atomic orbitals in the polyenes and a (28e,32o) active space and 278 atomic orbitals in [Cu(2)O(2)](2+).

Solving Eigenvalue response matrix equations with Jacobian-Free Newton-Krylov methods

International Nuclear Information System (INIS)

Roberts, Jeremy A.; Forget, Benoit

2011-01-01

The response matrix method for reactor eigenvalue problems is motivated as a technique for solving coarse mesh transport equations, and the classical approach of power iteration (PI) for solution is described. The method is then reformulated as a nonlinear system of equations, and the associated Jacobian is derived. A Jacobian-Free Newton-Krylov (JFNK) method is employed to solve the system, using an approximate Jacobian coupled with incomplete factorization as a preconditioner. The unpreconditioned JFNK slightly outperforms PI, and preconditioned JFNK outperforms both PI and Steffensen-accelerated PI significantly. (author)

Investigating the properties of six-quark bag by means of P-matrix

International Nuclear Information System (INIS)

Grach, I.L.; Veselov, A.I.; Konyukhova, N.B.; Shmatikov, M.Zh.

1983-01-01

The P-matrix for NN states with definite orbital momenta P 1 S 0 , 1 1 , 3 P 0 , 3 P 1 , 1 D 2 , 3 D 2 is calculated. The position of P-matrix poles determined from the results of phase shift analysis with the account of inelastic channels are compared to the predictions of the bag models for masses of six-quark states. The possible use of the low-energy behaviour of the P-matrix for the determination of the six-quark-bag radius is discussed

Quantitative proteomics reveals altered expression of extracellular matrix related proteins of human primary dermal fibroblasts in response to sulfated hyaluronan and collagen applied as artificial extracellular matrix.

Science.gov (United States)

Müller, Stephan A; van der Smissen, Anja; von Feilitzsch, Margarete; Anderegg, Ulf; Kalkhof, Stefan; von Bergen, Martin

2012-12-01

Fibroblasts are the main matrix producing cells of the dermis and are also strongly regulated by their matrix environment which can be used to improve and guide skin wound healing processes. Here, we systematically investigated the molecular effects on primary dermal fibroblasts in response to high-sulfated hyaluronan [HA] (hsHA) by quantitative proteomics. The comparison of non- and high-sulfated HA revealed regulation of 84 of more than 1,200 quantified proteins. Based on gene enrichment we found that sulfation of HA alters extracellular matrix remodeling. The collagen degrading enzymes cathepsin K, matrix metalloproteinases-2 and -14 were found to be down-regulated on hsHA. Additionally protein expression of thrombospondin-1, decorin, collagen types I and XII were reduced, whereas the expression of trophoblast glycoprotein and collagen type VI were slightly increased. This study demonstrates that global proteomics provides a valuable tool for revealing proteins involved in molecular effects of growth substrates for further material optimization.

Rational top and its classical r-matrix

International Nuclear Information System (INIS)

Aminov, G; Arthamonov, S; Smirnov, A; Zotov, A

2014-01-01

We construct a rational integrable system (the rational top) on a co-adjoint orbit of SL N Lie group. It is described by the Lax operator with spectral parameter and classical non-dynamical skew-symmetric r-matrix. In the case of the orbit of minimal dimension the model is gauge equivalent to the rational Calogero–Moser (CM) system. To obtain the results we represent the Lax operator of the CM model in two different factorized forms—without spectral parameter (related to the spinless case) and another one with the spectral parameter. The latter gives rise to the rational top while the first one is related to generalized Cremmer–Gervais r-matrices. The gauge transformation relating the rational top and CM model provides the classical rational version of the IRF-Vertex correspondence. From the geometrical point of view it describes the modification of SL(N,C)-bundles over degenerated elliptic curve. In view of the Symplectic Hecke Correspondence the rational top is related to the rational spin CM model. Possible applications and generalizations of the suggested construction are discussed. In particular, the obtained r-matrix defines a class of KZB equations. (paper)

Orbital-scale nonlinear response of East Asian summer monsoon to its potential driving forces in the late Quaternary

Science.gov (United States)

Yi, Liang; Shi, Zhengguo; Tan, Liangcheng; Deng, Chenglong

2018-03-01

We conducted a statistical study to characterize the nonlinear response of the East Asian summer monsoon (EASM) to its potential forcing factors over the last 260 ka on orbital timescales. We find that both variation in solar insolation and global ice volume were responsible for the nonlinear forcing of orbital-scale monsoonal variations, accounting for 80% of the total variance. Specifically, EASM records with dominated precession variance exhibit a more sensitive response to changes in solar insolation during intervals of enhanced monsoon strength, but are less sensitive during intervals of reduced monsoon strength. In the case of global ice volume with 100-ka variance, this difference is not one of sensitivity but rather a difference in baseline conditions, such as the relative areas of land and sea which affected the land-sea thermal gradient. We therefore suggest that EASM records with dominated precession variance recorded the signal of a shift in the location of the Inter-tropical Convergence Zone, and the associated changes in the incidence of torrential rainfall; while for proxies with dominated 100-ka variance, it recorded changes in the land-sea thermal gradient via its effects on non-torrential precipitation.

The acute orbit: Differentiation of orbital cellulitis from subperiosteal abscess by computerized tomography

International Nuclear Information System (INIS)

Handler, L.C.; Davey, I.C.; Hill, J.C.; Lauryssen, C.

1991-01-01

A series of 65 patients suffering from acute inflammatory disease of the orbit was studied by CT. Ethmoiditis was the cause in the vast majority; trauma and dental extraction played a lesser role in causation. Orbital cellulitis was diagnosed in 17 and subperiosteal abscess in the remaining 48. It was not possible to differentiate 33 pus-containing abscesses from the six with inflammatory masses (phlegmons). The satisfactory response to aggressive medical treatment in those patients with inflammatory masses that were not drained justifies a more conservative approach; surgical drainage being reserved for those with a deterioration in proptosis, ocular movements or vision. Six abscesses arose de novo, of which some were in the orbital fat rather than the subperiosteal space. (orig.)

Chemical bonding analysis for solid-state systems using intrinsic oriented quasiatomic minimal-basis-set orbitals

International Nuclear Information System (INIS)

Yao, Y.X.; Wang, C.Z.; Ho, K.M.

2010-01-01

A chemical bonding scheme is presented for the analysis of solid-state systems. The scheme is based on the intrinsic oriented quasiatomic minimal-basis-set orbitals (IO-QUAMBOs) previously developed by Ivanic and Ruedenberg for molecular systems. In the solid-state scheme, IO-QUAMBOs are generated by a unitary transformation of the quasiatomic orbitals located at each site of the system with the criteria of maximizing the sum of the fourth power of interatomic orbital bond order. Possible bonding and antibonding characters are indicated by the single particle matrix elements, and can be further examined by the projected density of states. We demonstrate the method by applications to graphene and (6,0) zigzag carbon nanotube. The oriented-orbital scheme automatically describes the system in terms of sp 2 hybridization. The effect of curvature on the electronic structure of the zigzag carbon nanotube is also manifested in the deformation of the intrinsic oriented orbitals as well as a breaking of symmetry leading to nonzero single particle density matrix elements. In an additional study, the analysis is performed on the Al 3 V compound. The main covalent bonding characters are identified in a straightforward way without resorting to the symmetry analysis. Our method provides a general way for chemical bonding analysis of ab initio electronic structure calculations with any type of basis sets.

Linear orbit parameters for the exact equations of motion

International Nuclear Information System (INIS)

Parzen, G.

1995-01-01

This paper defines the beta function and other linear orbit parameters using the exact equations of motion. The β, α and ψ functions are redefined using the exact equations. Expressions are found for the transfer matrix and the emittance. The differential equations for η = x/β 1/2 is found. New relationships between α, β, ψ and ν are derived

Computed tomography of orbital myositis

International Nuclear Information System (INIS)

Dresner, S.C.; Rothfus, W.E.; Slamovits, T.L.; Kennerdell, J.S.; Curtin, H.D.

1984-01-01

The computerized tomographic (CT) scans of 11 consecutive patients with orbital myositis were reviewed to better characterize the CT appearance of this condition. The findings in this series differed from those of previous reports in several ways. Multiple muscle involvement predominated. Bilateral involvement was more frequent than previously reported. Enlargement of the tendon as well as the muscle was a frequent finding, but a normal tendinous insertion did not preclude the diagnosis of orbital myositis. Although the CT appearance of orbital myositis is often helpful, the findings are not pathognomonic; correlation with history, clinical findings, and therapeutic response must be considered in making the diagnosis

IMMUNE RESPONSE TO EXTRACELLULAR MATRIX COLLAGEN IN CHRONIC HEPATITIS C INDUCED LIVER FIBROSIS

OpenAIRE

Borg, Brian B.; Seetharam, Anil; Subramanian, Vijay; Ilias, Haseeb; Lisker–Melman, Mauricio; Korenblat, Kevin; Anderson, Christopher; Shenoy, Surendra; Chapman, William C.; Crippin, Jeffrey S.; Mohanakumar, Thalachallour

2011-01-01

Hepatitis C Virus (HCV) infection and recurrence post-transplant (OLT) is associated with extracellular matrix (ECM) components remodeling, particularly collagen (Col), leading to fibrosis. Our aim was to determine whether development of antibodies (Abs) to self antigen Col in HCV infection correlates with fibrosis stage and peripheral cytokine response. Chronic HCV patients, those with recurrence after OLT undergoing biopsy and healthy control subjects were enrolled. HCV subjects (n=70) were...

Λ hypernuclei in the Skyrme-Hartree-Fock treatment with G-matrix motivated interactions

International Nuclear Information System (INIS)

Lanskoy, D.E.; Yamamoto, Y.

1997-01-01

Skyrme-like hyperon-nucleon potentials are derived from G-matrix calculations and shown to reproduce well the Λ single-particle spectra of hypernuclei measured in BNL and KEK. Fit of the spectra can restrict p-wave ΛN interaction, radii of Λ orbits in hypernuclear ground states, Λ well depth and effective mass in nuclear matter rather tightly. Implications of ΛN spin-orbit force to the spectra are considered. (author)

Multiscale Modeling of Ceramic Matrix Composites

Science.gov (United States)

Bednarcyk, Brett A.; Mital, Subodh K.; Pineda, Evan J.; Arnold, Steven M.

2015-01-01

Results of multiscale modeling simulations of the nonlinear response of SiC/SiC ceramic matrix composites are reported, wherein the microstructure of the ceramic matrix is captured. This micro scale architecture, which contains free Si material as well as the SiC ceramic, is responsible for residual stresses that play an important role in the subsequent thermo-mechanical behavior of the SiC/SiC composite. Using the novel Multiscale Generalized Method of Cells recursive micromechanics theory, the microstructure of the matrix, as well as the microstructure of the composite (fiber and matrix) can be captured.

Comment on "Nonuniqueness of algebraic first-order density-matrix functionals"

Science.gov (United States)

Gritsenko, O. V.

2018-02-01

Wang and Knowles (WK) [Phys. Rev. A 92, 012520 (2015), 10.1103/PhysRevA.92.012520] have given a counterexample to the conventional in reduced density-matrix functional theory representation of the second-order reduced density matrix (2RDM) Γi j ,k l in the basis of the natural orbitals as a function Γi j ,k l(n ) of the orbital occupation numbers (ONs) ni. The observed nonuniqueness of Γi j ,k l for prototype systems of different symmetry has been interpreted as the inherent inability of ON functions to reproduce the 2RDM, due to the insufficient information contained in the 1RDM spectrum. In this Comment, it is argued that, rather than totally invalidating Γi j ,k l(n ) , the WK example exposes its symmetry dependence which, as well as the previously established analogous dependence in density functional theory, is demonstrated with a general formulation based on the Levy constrained search.

The Dynamic Response of an Euler-Bernoulli Beam on an Elastic Foundation by Finite Element Analysis using the Exact Stiffness Matrix

International Nuclear Information System (INIS)

Kim, Jeong Soo; Kim, Moon Kyum

2012-01-01

In this study, finite element analysis of beam on elastic foundation, which received great attention of researchers due to its wide applications in engineering, is performed for estimating dynamic responses of shallow foundation using exact stiffness matrix. First, element stiffness matrix based on the closed solution of beam on elastic foundation is derived. Then, we performed static finite element analysis included exact stiffness matrix numerically, comparing results from the analysis with some exact analysis solutions well known for verification. Finally, dynamic finite element analysis is performed for a shallow foundation structure under rectangular pulse loading using trapezoidal method. The dynamic analysis results exist in the reasonable range comparing solution of single degree of freedom problem under a similar condition. The results show that finite element analysis using exact stiffness matrix is evaluated as a good tool of estimating the dynamic response of structures on elastic foundation.

Thermal and mechanical behavior of metal matrix and ceramic matrix composites

Science.gov (United States)

Kennedy, John M. (Editor); Moeller, Helen H. (Editor); Johnson, W. S. (Editor)

1990-01-01

The present conference discusses local stresses in metal-matrix composites (MMCs) subjected to thermal and mechanical loads, the computational simulation of high-temperature MMCs' cyclic behavior, an analysis of a ceramic-matrix composite (CMC) flexure specimen, and a plasticity analysis of fibrous composite laminates under thermomechanical loads. Also discussed are a comparison of methods for determining the fiber-matrix interface frictional stresses of CMCs, the monotonic and cyclic behavior of an SiC/calcium aluminosilicate CMC, the mechanical and thermal properties of an SiC particle-reinforced Al alloy MMC, the temperature-dependent tensile and shear response of a graphite-reinforced 6061 Al-alloy MMC, the fiber/matrix interface bonding strength of MMCs, and fatigue crack growth in an Al2O3 short fiber-reinforced Al-2Mg matrix MMC.

Stability regions for synchronized τ-periodic orbits of coupled maps with coupling delay τ

Energy Technology Data Exchange (ETDEWEB)

Karabacak, Özkan, E-mail: ozkan2917@gmail.com [Department of Electronics and Communication Engineering, Istanbul Technical University, 34469 Istanbul (Turkey); Department of Electronic Systems, Aalborg University, 9220 Aalborg East (Denmark); Alikoç, Baran, E-mail: alikoc@itu.edu.tr [Department of Control and Automation Engineering, Istanbul Technical University, 34469 Istanbul (Turkey); Atay, Fatihcan M., E-mail: atay@member.ams.org [Department of Mathematics, Bilkent University, 06800 Ankara (Turkey)

2016-09-15

Motivated by the chaos suppression methods based on stabilizing an unstable periodic orbit, we study the stability of synchronized periodic orbits of coupled map systems when the period of the orbit is the same as the delay in the information transmission between coupled units. We show that the stability region of a synchronized periodic orbit is determined by the Floquet multiplier of the periodic orbit for the uncoupled map, the coupling constant, the smallest and the largest Laplacian eigenvalue of the adjacency matrix. We prove that the stabilization of an unstable τ-periodic orbit via coupling with delay τ is possible only when the Floquet multiplier of the orbit is negative and the connection structure is not bipartite. For a given coupling structure, it is possible to find the values of the coupling strength that stabilizes unstable periodic orbits. The most suitable connection topology for stabilization is found to be the all-to-all coupling. On the other hand, a negative coupling constant may lead to destabilization of τ-periodic orbits that are stable for the uncoupled map. We provide examples of coupled logistic maps demonstrating the stabilization and destabilization of synchronized τ-periodic orbits as well as chaos suppression via stabilization of a synchronized τ-periodic orbit.

Single-particle spin-orbit potentials of the LAMBDA and SIGMA hyperons based on the quark-model G-matrix

CERN Document Server

Kohno, M; Fujita, T; Nakamoto, C; Suzuki, Y

2000-01-01

Using the SU sub 6 quark-model baryon-baryon interaction which was recently developed by the Kyoto-Niigata group, we calculate N N, LAMBDA N and SIGMA N G--matrices in ordinary nuclear matter. Following the Scheerbaum's prescription, the strength of the single-particle spin-orbit potential S sub B is quantitatively discussed. The S subLAMBDA becomes small because of the cancellation between spin-orbit and anti-symmetric spin-orbit components. The short-range correlation is found to further reduce S subLAMBDA.

A comprehensive analysis of molecule-intrinsic quasi-atomic, bonding, and correlating orbitals. I. Hartree-Fock wave functions

International Nuclear Information System (INIS)

West, Aaron C.; Schmidt, Michael W.; Gordon, Mark S.; Ruedenberg, Klaus

2013-01-01

Through a basis-set-independent web of localizing orbital-transformations, the electronic wave function of a molecule is expressed in terms of a set of orbitals that reveal the atomic structure and the bonding pattern of a molecule. The analysis is based on resolving the valence orbital space in terms of an internal space, which has minimal basis set dimensions, and an external space. In the internal space, oriented quasi-atomic orbitals and split-localized molecular orbitals are determined by new, fast localization methods. The density matrix between the oriented quasi-atomic orbitals as well as the locations of the split-localized orbitals exhibit atomic populations and inter-atomic bonding patterns. A correlation-adapted quasi-atomic basis is determined in the external orbital space. The general formulations are specified in detail for Hartree-Fock wave functions. Applications to specific molecules exemplify the general scheme

Research on the Effectiveness of Different Estimation Algorithm on the Autonomous Orbit Determination of Lagrangian Navigation Constellation

Directory of Open Access Journals (Sweden)

Youtao Gao

2016-01-01

Full Text Available The accuracy of autonomous orbit determination of Lagrangian navigation constellation will affect the navigation accuracy for the deep space probes. Because of the special dynamical characteristics of Lagrangian navigation satellite, the error caused by different estimation algorithm will cause totally different autonomous orbit determination accuracy. We apply the extended Kalman filter and the fading–memory filter to determinate the orbits of Lagrangian navigation satellites. The autonomous orbit determination errors are compared. The accuracy of autonomous orbit determination using fading-memory filter can improve 50% compared to the autonomous orbit determination accuracy using extended Kalman filter. We proposed an integrated Kalman fading filter to smooth the process of autonomous orbit determination and improve the accuracy of autonomous orbit determination. The square root extended Kalman filter is introduced to deal with the case of inaccurate initial error variance matrix. The simulations proved that the estimation method can affect the accuracy of autonomous orbit determination greatly.

Quasiparticle semiconductor band structures including spin-orbit interactions.

Science.gov (United States)

Malone, Brad D; Cohen, Marvin L

2013-03-13

We present first-principles calculations of the quasiparticle band structure of the group IV materials Si and Ge and the group III-V compound semiconductors AlP, AlAs, AlSb, InP, InAs, InSb, GaP, GaAs and GaSb. Calculations are performed using the plane wave pseudopotential method and the 'one-shot' GW method, i.e. G(0)W(0). Quasiparticle band structures, augmented with the effects of spin-orbit, are obtained via a Wannier interpolation of the obtained quasiparticle energies and calculated spin-orbit matrix. Our calculations explicitly treat the shallow semicore states of In and Ga, which are known to be important in the description of the electronic properties, as valence states in the quasiparticle calculation. Our calculated quasiparticle energies, combining both the ab initio evaluation of the electron self-energy and the vector part of the pseudopotential representing the spin-orbit effects, are in generally very good agreement with experimental values. These calculations illustrate the predictive power of the methodology as applied to group IV and III-V semiconductors.

Tailoring spin-orbit torque in diluted magnetic semiconductors

KAUST Repository

Li, Hang; Wang, Xuhui; Doǧan, Fatih; Manchon, Aurelien

2013-01-01

We study the spin orbit torque arising from an intrinsic linear Dresselhaus spin-orbit coupling in a single layer III-V diluted magnetic semiconductor. We investigate the transport properties and spin torque using the linear response theory, and we report here: (1) a strong correlation exists between the angular dependence of the torque and the anisotropy of the Fermi surface; (2) the spin orbit torque depends nonlinearly on the exchange coupling. Our findings suggest the possibility to tailor the spin orbit torque magnitude and angular dependence by structural design.

Tailoring spin-orbit torque in diluted magnetic semiconductors

KAUST Repository

Li, Hang

2013-05-16

We study the spin orbit torque arising from an intrinsic linear Dresselhaus spin-orbit coupling in a single layer III-V diluted magnetic semiconductor. We investigate the transport properties and spin torque using the linear response theory, and we report here: (1) a strong correlation exists between the angular dependence of the torque and the anisotropy of the Fermi surface; (2) the spin orbit torque depends nonlinearly on the exchange coupling. Our findings suggest the possibility to tailor the spin orbit torque magnitude and angular dependence by structural design.

Biomimetic and enzyme-responsive dynamic hydrogels for studying cell-matrix interactions in pancreatic ductal adenocarcinoma.

Science.gov (United States)

Liu, Hung-Yi; Korc, Murray; Lin, Chien-Chi

2018-04-01

The tumor microenvironment (TME) governs all aspects of cancer progression and in vitro 3D cell culture platforms are increasingly developed to emulate the interactions between components of the stromal tissues and cancer cells. However, conventional cell culture platforms are inadequate in recapitulating the TME, which has complex compositions and dynamically changing matrix mechanics. In this study, we developed a dynamic gelatin-hyaluronic acid hybrid hydrogel system through integrating modular thiol-norbornene photopolymerization and enzyme-triggered on-demand matrix stiffening. In particular, gelatin was dually modified with norbornene and 4-hydroxyphenylacetic acid to render this bioactive protein photo-crosslinkable (through thiol-norbornene gelation) and responsive to tyrosinase-triggered on-demand stiffening (through HPA dimerization). In addition to the modified gelatin that provides basic cell adhesive motifs and protease cleavable sequences, hyaluronic acid (HA), an essential tumor matrix, was modularly and covalently incorporated into the cell-laden gel network. We systematically characterized macromer modification, gel crosslinking, as well as enzyme-triggered stiffening and degradation. We also evaluated the influence of matrix composition and dynamic stiffening on pancreatic ductal adenocarcinoma (PDAC) cell fate in 3D. We found that either HA-containing matrix or a dynamically stiffened microenvironment inhibited PDAC cell growth. Interestingly, these two factors synergistically induced cell phenotypic changes that resembled cell migration and/or invasion in 3D. Additional mRNA expression array analyses revealed changes unique to the presence of HA, to a stiffened microenvironment, or to the combination of both. Finally, we presented immunostaining and mRNA expression data to demonstrate that these irregular PDAC cell phenotypes were a result of matrix-induced epithelial-mesenchymal transition (EMT). Copyright © 2018 Elsevier Ltd. All rights

Physiological responses of astronaut candidates to simulated +Gx orbital emergency re-entry.

Science.gov (United States)

Wu, Bin; Xue, Yueying; Wu, Ping; Gu, Zhiming; Wang, Yue; Jing, Xiaolu

2012-08-01

We investigated astronaut candidates' physiological and pathological responses to +Gx exposure during simulated emergency return from a running orbit to advance astronaut +Gx tolerance training and medical support in manned spaceflight. There were 13 male astronaut candidates who were exposed to a simulated high +Gx acceleration profile in a spacecraft during an emergency return lasting for 230 s. The peak value was 8.5 G. Subjective feelings and symptoms, cardiovascular and respiratory responses, and changes in urine component before, during, and after +Gx exposure were investigated. Under high +Gx exposure, 15.4% of subjects exhibited arrhythmia. Heart rate (HR) increased significantly and four different types of HR response curves were distinguished. The ratio of QT to RR interval on the electrocardiograms was significantly increased. Arterial oxygen saturation (SaO2) declined with increasing G value and then returned gradually. SaO2 reached a minimum (87.7%) at 3 G during the decline phase of the +Gx curve. Respiratory rate increased significantly with increasing G value, while the amplitude and area of the respiratory waves were significantly reduced. The overshoot appeared immediately after +Gx exposure. A few subjects suffered from slight injuries, including positive urine protein (1/13), positive urinary occult blood (1/13), and a large area of petechiae on the back (1/13). Astronaut candidates have relatively good tolerance to the +Gx profile during a simulation of spacecraft emergent ballistic re-entry. However, a few subjects exhibited adverse physiological responses and slight reversible pathological injuries.

Matrix Stiffness Corresponding to Strictured Bowel Induces a Fibrogenic Response in Human Colonic Fibroblasts

Science.gov (United States)

Johnson, Laura A.; Rodansky, Eva S.; Sauder, Kay L.; Horowitz, Jeffrey C.; Mih, Justin D.; Tschumperlin, Daniel J.; Higgins, Peter D.

2013-01-01

Background Crohn’s disease is characterized by repeated cycles of inflammation and mucosal healing which ultimately progress to intestinal fibrosis. This inexorable progression towards fibrosis suggests that fibrosis becomes inflammation-independent and auto-propagative. We hypothesized that matrix stiffness regulates this auto-propagation of intestinal fibrosis. Methods The stiffness of fresh ex vivo samples from normal human small intestine, Crohn’s disease strictures, and the unaffected margin were measured with a microelastometer. Normal human colonic fibroblasts were cultured on physiologically normal or pathologically stiff matrices corresponding to the physiological stiffness of normal or fibrotic bowel. Cellular response was assayed for changes in cell morphology, α-smooth muscle actin (αSMA) staining, and gene expression. Results Microelastometer measurements revealed a significant increase in colonic tissue stiffness between normal human colon and Crohn’s strictures as well as between the stricture and adjacent tissue margin. In Ccd-18co cells grown on stiff matrices corresponding to Crohn’s strictures, cellular proliferation increased. Pathologic stiffness induced a marked change in cell morphology and increased αSMA protein expression. Growth on a stiff matrix induced fibrogenic gene expression, decreased matrix metalloproteinase and pro-inflammatory gene expression, and was associated with nuclear localization of the transcriptional cofactor MRTF-A. Conclusions Matrix stiffness, representative of the pathological stiffness of Crohn’s strictures, activates human colonic fibroblasts to a fibrogenic phenotype. Matrix stiffness affects multiple pathways suggesting the mechanical properties of the cellular environment are critical to fibroblast function and may contribute to autopropagation of intestinal fibrosis in the absence of inflammation, thereby contributing to the intractable intestinal fibrosis characteristic of Crohn’s disease. PMID

Advances in orbit drift correction in the advanced photon source storage ring

International Nuclear Information System (INIS)

Emery, L.; Borland, M.

1997-01-01

The Advanced Photon Source storage ring is required to provide X-ray beams of high positional stability, specified as 17 μm rms in the horizontal plane and 4.4 μm rms in the vertical plane. The author reports on the difficult task of stabilizing the slow drift component of the orbit motion down to a few microns rms using workstation-based orbit correction. There are two aspects to consider separately the correction algorithm and the configuration of the beam position monitors (BPMs) and correctors. Three notable features of the correction algorithm are: low-pass digital filtering of BPM readbacks; open-quotes despikingclose quotes of the filtered orbit to desensitize the orbit correction to spurious BPM readbacks without having to change the correction matrix; and BPM intensity-dependent offset compensation. The BPM/corrector configuration includes all of the working BPMs but only a small set of correctors distributed around the ring. Thus only those orbit modes that are most likely to be representative of real beam drift are handled by the correction algorithm

A semi-analytical method to evaluate the dielectric response of a tokamak plasma accounting for drift orbit effects

Science.gov (United States)

Van Eester, Dirk

2005-03-01

A semi-analytical method is proposed to evaluate the dielectric response of a plasma to electromagnetic waves in the ion cyclotron domain of frequencies in a D-shaped but axisymmetric toroidal geometry. The actual drift orbit of the particles is accounted for. The method hinges on subdividing the orbit into elementary segments in which the integrations can be performed analytically or by tabulation, and it relies on the local book-keeping of the relation between the toroidal angular momentum and the poloidal flux function. Depending on which variables are chosen, the method allows computation of elementary building blocks for either the wave or the Fokker-Planck equation, but the accent is mainly on the latter. Two types of tangent resonance are distinguished.

Tissue specificity of the hormonal response in sex accessory tissues is associated with nuclear matrix protein patterns.

Science.gov (United States)

Getzenberg, R H; Coffey, D S

1990-09-01

The DNA of interphase nuclei have very specific three-dimensional organizations that are different in different cell types, and it is possible that this varying DNA organization is responsible for the tissue specificity of gene expression. The nuclear matrix organizes the three-dimensional structure of the DNA and is believed to be involved in the control of gene expression. This study compares the nuclear structural proteins between two sex accessory tissues in the same animal responding to the same androgen stimulation by the differential expression of major tissue-specific secretory proteins. We demonstrate here that the nuclear matrix is tissue specific in the rat ventral prostate and seminal vesicle, and undergoes characteristic alterations in its protein composition upon androgen withdrawal. Three types of nuclear matrix proteins were observed: 1) nuclear matrix proteins that are different and tissue specific in the rat ventral prostate and seminal vesicle, 2) a set of nuclear matrix proteins that either appear or disappear upon androgen withdrawal, and 3) a set of proteins that are common to both the ventral prostate and seminal vesicle and do not change with the hormonal state of the animal. Since the nuclear matrix is known to bind androgen receptors in a tissue- and steroid-specific manner, we propose that the tissue specificity of the nuclear matrix arranges the DNA in a unique conformation, which may be involved in the specific interaction of transcription factors with DNA sequences, resulting in tissue-specific patterns of secretory protein expression.

Robust Tracking Control for Rendezvous in Near-Circular Orbits

Directory of Open Access Journals (Sweden)

Neng Wan

2013-01-01

Full Text Available This paper investigates a robust guaranteed cost tracking control problem for thrust-limited spacecraft rendezvous in near-circular orbits. Relative motion model is established based on the two-body problem with noncircularity of the target orbit described as a parameter uncertainty. A guaranteed cost tracking controller with input saturation is designed via a linear matrix inequality (LMI method, and sufficient conditions for the existence of the robust tracking controller are derived, which is more concise and less conservative compared with the previous works. Numerical examples are provided for both time-invariant and time-variant reference signals to illustrate the effectiveness of the proposed control scheme when applied to the terminal rendezvous and other astronautic missions with scheduled states signal.

Cytokine and matrix metalloproteinase expression in fibroblasts from peri-implantitis lesions in response to viable Porphyromonas gingivalis

NARCIS (Netherlands)

Irshad, M.; Scheres, N.; Anssari Moin, D.; Crielaard, W.; Loos, B.G.; Wismeijer, D.; Laine, M.L.

2013-01-01

Background and Objective To assess inflammatory reactions of fibroblasts in the pathophysiology of peri-implantitis, we compared the pro-inflammatory and matrix-degrading responses of gingival and granulation tissue fibroblasts from periodontally healthy controls, peri-implantitis, and periodontitis

Matrix Metalloproteinases Are Differentially Regulated and Responsive to Compression Therapy in a Red Duroc Model of Hypertrophic Scar.

Science.gov (United States)

Travis, Taryn E; Ghassemi, Pejhman; Prindeze, Nicholas J; Moffatt, Lauren T; Carney, Bonnie C; Alkhalil, Abdulnaser; Ramella-Roman, Jessica C; Shupp, Jeffrey W

2018-01-01

Objective: Proteins of the matrix metalloproteinases family play a vital role in extracellular matrix maintenance and basic physiological processes in tissue homeostasis. The function and activities of matrix metalloproteinases in response to compression therapies have yet to be defined. Here, a swine model of hypertrophic scar was used to profile the transcription of all known 26 matrix metalloproteinases in scars treated with a precise compression dose. Methods: Full-thickness excisional wounds were created. Wounds underwent healing and scar formation. A subset of scars underwent 2 weeks of compression therapy. Biopsy specimens were preserved, and microarrays, reverse transcription-polymerase chain reaction, Western blotting, and immunohistochemistry were performed to characterize the transcription and expression of various matrix metalloproteinase family members. Results: Microarray results showed that 13 of the known 26 matrix metalloproteinases were differentially transcribed in wounds relative to the preinjury skin. The predominant upregulation of these matrix metalloproteinases during early wound-healing stages declined gradually in later stages of wound healing. The use of compression therapy reduced this decline in 10 of the 13 differentially regulated matrix metalloproteinases. Further investigation of MMP7 using reverse transcription-polymerase chain reaction confirmed the effect of compression on transcript levels. Assessment of MMP7 at the protein level using Western blotting and immunohistochemistry was concordant. Conclusions: In a swine model of hypertrophic scar, the application of compression to hypertrophic scar attenuated a trend of decreasing levels of matrix metalloproteinases during the process of hypertrophic wound healing, including MMP7, whose enzyme regulation was confirmed at the protein level.

Investigate the plant biomass response to climate warming in permafrost ecosystem using matrix-based data assimilation

Science.gov (United States)

Lu, X.; Du, Z.; Schuur, E.; Luo, Y.

2017-12-01

Permafrost is one of the most vulnerable regions on the earth with over 40% world soil C represented in this region. Future climate warming potentially has a great impact on this region. On one hand, rising temperature accelerates permafrost soil thaw and release more C from land. On the other hand, warming may also increase the plant growing season length and therefore negatively feedback to climate change by increasing annual land C uptake. However, whether permafrost vegetation biomass change in response to warming can sequester more C has not been well understood. Manipulated air warming experiments reported that air warming has very limited impacts on grass land productivity and biomass growth in permafrost region [Mauritz et al., 2017]. It is hard to reveal the mechanisms behind the limited air warming response directly from experiment data. We employ a vegetation C cycle matrix model based on Community land model 4.5 (CLM4.5) and data assimilation technique to investigate how much do phenology and physiology processes contribute to the response respectively. Our results indicate phenology contributes the most in response to warming. The shift of vegetation parameter distributions after 2012 indicate vegetation acclimation may explain the modest response in plant biomass to air warming. The results suggest future model development need to take vegetation acclimation more seriously. The novel matrix-based model allows data assimilation to be conducted more efficiently. It provides more functional understanding of the models as well as the mechanism behind experiment data.

Study on the Seismic Response of a Portal Frame Structure Based on the Transfer Matrix Method of Multibody System

Directory of Open Access Journals (Sweden)

Jianguo Ding

2014-11-01

Full Text Available Portal frame structures are widely used in industrial building design but unfortunately are often damaged during an earthquake. As a result, a study on the seismic response of this type of structure is important to both human safety and future building designs. Traditionally, finite element methods such as the ANSYS and MIDAS have been used as the primary methods of computing the response of such a structure during an earthquake; however, these methods yield low calculation efficiencies. In this paper, the mechanical model of a single-story portal frame structure with two spans is constructed based on the transfer matrix method of multibody system (MS-TMM; both the transfer matrix of the components in the model and the total transfer matrix equation of the structure are derived, and the corresponding MATLAB program is compiled to determine the natural period and seismic response of the structure. The results show that the results based on the MS-TMM are similar to those obtained by ANSYS, but the calculation time of the MS-TMM method is only 1/20 of that of the ANSYS method. Additionally, it is shown that the MS-TMM method greatly increases the calculation efficiency while maintaining accuracy.

A new seniority scheme for non-degenerate single particle orbits

International Nuclear Information System (INIS)

Otsuka, T.; Arima, A.

1978-01-01

A new method is proposed in the treatment of the seniority scheme. The method enables one to evaluate analytically the contribution from J = 0 Cooper pairs in non-degenerate single-particle orbits to many-body matrix elements. It includes the SU(2) quasi-spin and the BCS approximation as two extreme limits. The effect of particle number conservation is properly taken into account. (Auth.)

Structure of the first order reduced density matrix in three electron systems: A generalized Pauli constraints assisted study.

Science.gov (United States)

Theophilou, Iris; Lathiotakis, Nektarios N; Helbig, Nicole

2018-03-21

We investigate the structure of the one-body reduced density matrix of three electron systems, i.e., doublet and quadruplet spin configurations, corresponding to the smallest interacting system with an open-shell ground state. To this end, we use configuration interaction (CI) expansions of the exact wave function in Slater determinants built from natural orbitals in a finite dimensional Hilbert space. With the exception of maximally polarized systems, the natural orbitals of spin eigenstates are generally spin dependent, i.e., the spatial parts of the up and down natural orbitals form two different sets. A measure to quantify this spin dependence is introduced and it is shown that it varies by several orders of magnitude depending on the system. We also study the ordering issue of the spin-dependent occupation numbers which has practical implications in reduced density matrix functional theory minimization schemes, when generalized Pauli constraints (GPCs) are imposed and in the form of the CI expansion in terms of the natural orbitals. Finally, we discuss the aforementioned CI expansion when there are GPCs that are almost "pinned."

Structure of the first order reduced density matrix in three electron systems: A generalized Pauli constraints assisted study

Science.gov (United States)

Theophilou, Iris; Lathiotakis, Nektarios N.; Helbig, Nicole

2018-03-01

We investigate the structure of the one-body reduced density matrix of three electron systems, i.e., doublet and quadruplet spin configurations, corresponding to the smallest interacting system with an open-shell ground state. To this end, we use configuration interaction (CI) expansions of the exact wave function in Slater determinants built from natural orbitals in a finite dimensional Hilbert space. With the exception of maximally polarized systems, the natural orbitals of spin eigenstates are generally spin dependent, i.e., the spatial parts of the up and down natural orbitals form two different sets. A measure to quantify this spin dependence is introduced and it is shown that it varies by several orders of magnitude depending on the system. We also study the ordering issue of the spin-dependent occupation numbers which has practical implications in reduced density matrix functional theory minimization schemes, when generalized Pauli constraints (GPCs) are imposed and in the form of the CI expansion in terms of the natural orbitals. Finally, we discuss the aforementioned CI expansion when there are GPCs that are almost "pinned."

Single-Particle Spin-Orbit Splittings in Nuclei

OpenAIRE

Kazuhiko, ANDO; Hiroharu, BANDO; Department of Physics, Kyoto University; Division of Mathematical Physics, Fukui University

1981-01-01

Single-particle spin-orbit splittings (Δ^) in ^O and ^Ca nuclei are evaluated within the framework of the effective interaction theory by employing the Reid soft-core potential and meson-exchange three-body forces (TBF). Among the two-body force contributions, the Pauli-rearrangement effect on Δ^ is studied with special care. The TBF contribution to Δ^ is found to be significant. The G-matrix, the second-order pauli-rearrangement and the TBF contribute to Δ^ by the amount of ～1/2, ～1/5 and ～1...

Asymmetric current-phase relation due to spin-orbit interaction in semiconductor nanowire Josephson junction

NARCIS (Netherlands)

Yokoyama, T.; Eto, M.; Nazarov, Y.V.

2012-01-01

We theoretically study the current-phase relation in semiconductor nanowire Josephson junction in the presence of spin-orbit interaction. In the nanowire, the impurity scattering with strong SO interaction is taken into account using the random matrix theory. In the absence of magnetic field, the

Spin-flip and spin orbit interactions in heavy ion systems

International Nuclear Information System (INIS)

Bybell, D.P.

1983-01-01

The role of spin orbit forces in heavy ion reactions is not completely understood. Experimental data is scarce for these systems but the data that does exist indicates a stronger spin orbit force than predicted by the folding models. The spin-flip probability of non-spin zero projectiles is one technique used for these measurements and is often taken as a direct indicator of a spin orbit interaction. This work measures the projectile spin-flip probability for three inelastic reactions; 13 C + 24 Mg, E/sub cm/ = 22.7 MeV; 13 C + 12 C, E/sub cm/ = 17.3 MeV; and 6 Li + 12 C, E/sub cm/ = 15.2 MeV, all leading to the first J/sup π/ = 2 + state of the target. The technique of particle-γ angular correlations was used for measuring the final state density matrix elements, of which the absolute value M = 1 magnetic substate population is equivalent to the spin-flip probability. The method was explored in detail and found to be sensitive to spin-flip probabilities smaller than 1%. The technique was also found to be a good indicator of the reaction mechanism involved. Nonzero and occasionally large spin-flip probabilities were observed in all systems, much larger than the folding model predictions. Information was obtained on the non-spin-flip density matrix elements. In the 13 C + 24 Mg reaction, these were found to agree with calculations when the finite size of the particle detector is included

Leptospira interrogans induces uterine inflammatory responses and abnormal expression of extracellular matrix proteins in dogs.

Science.gov (United States)

Wang, Wei; Gao, Xuejiao; Guo, Mengyao; Zhang, Wenlong; Song, Xiaojing; Wang, Tiancheng; Zhang, Zecai; Jiang, Haichao; Cao, Yongguo; Zhang, Naisheng

2014-10-01

Leptospira interrogans (L. interrogans), a worldwide zoonosis, infect humans and animals. In dogs, four syndromes caused by leptospirosis have been identified: icteric, hemorrhagic, uremic (Stuttgart disease) and reproductive (abortion and premature or weak pups), and also it caused inflammation. Extracellular matrix (ECM) is a complex mixture of matrix molecules that is crucial to the reproduction. Both inflammatory response and ECM are closed relative to reproductive. The aim of this study was to clarify how L. interrogans affected the uterus of dogs, by focusing on the inflammatory responses, and ECM expression in dogs uterine tissue infected by L. interrogans. In the present study, 27 dogs were divided into 3 groups, intrauterine infusion with L. interrogans, to make uterine infection, sterile EMJH, and normal saline as a control, respectively. The uteruses were removed by surgical operation in 10, 20, and 30 days, respectively. The methods of histopathological analysis, ELISA, Western blot and qPCR were used. The results showed that L. interrogans induced significantly inflammatory responses, which were characterized by inflammatory cellular infiltration and high expression levels of tumor necrosis factor α (TNF-α), interleukin-1β (IL-1β) and interleukin-6 (IL-6) in uterine tissue of these dogs. Furthermore, L. interrogans strongly down-regulated the expression of ECM (collagens (CL) IV, fibronectins (FN) and laminins (LN)) in mRNA and protein levels. These data indicated that strongly inflammatory responses, and abnormal regulation of ECM might contribute to the proliferation of dogs infected by L. interrogans. Copyright © 2014 Elsevier Ltd. All rights reserved.

Electronic orbital response of regular extended and infinite periodic systems to magnetic fields. I. Theoretical foundations for static case

Science.gov (United States)

Springborg, Michael; Molayem, Mohammad; Kirtman, Bernard

2017-09-01

A theoretical treatment for the orbital response of an infinite, periodic system to a static, homogeneous, magnetic field is presented. It is assumed that the system of interest has an energy gap separating occupied and unoccupied orbitals and a zero Chern number. In contrast to earlier studies, we do not utilize a perturbation expansion, although we do assume the field is sufficiently weak that the occurrence of Landau levels can be ignored. The theory is developed by analyzing results for large, finite systems and also by comparing with the analogous treatment of an electrostatic field. The resulting many-electron Hamilton operator is forced to be hermitian, but hermiticity is not preserved, in general, for the subsequently derived single-particle operators that determine the electronic orbitals. However, we demonstrate that when focusing on the canonical solutions to the single-particle equations, hermiticity is preserved. The issue of gauge-origin dependence of approximate solutions is addressed. Our approach is compared with several previously proposed treatments, whereby limitations in some of the latter are identified.

An immunofluorescence assay for extracellular matrix components highlights the role of epithelial cells in producing a stable, fibrillar extracellular matrix

Directory of Open Access Journals (Sweden)

Omar S. Qureshi

2017-10-01

Full Text Available Activated fibroblasts are considered major drivers of fibrotic disease progression through the production of excessive extracellular matrix (ECM in response to signals from damaged epithelial and inflammatory cells. Nevertheless, epithelial cells are capable of expressing components of the ECM, cross-linking enzymes that increase its stability and are sensitive to factors involved in the early stages of fibrosis. We therefore wanted to test the hypothesis that epithelial cells can deposit ECM in response to stimulation in a comparable manner to fibroblasts. We performed immunofluorescence analysis of components of stable, mature extracellular matrix produced by primary human renal proximal tubular epithelial cells and renal fibroblasts in response to cytokine stimulation. Whilst fibroblasts produced a higher basal level of extracellular matrix components, epithelial cells were able to deposit significant levels of fibronectin, collagen I, III and IV in response to cytokine stimulation. In response to hypoxia, epithelial cells showed an increase in collagen IV deposition but not in response to the acute stress stimuli aristolochic acid or hydrogen peroxide. When epithelial cells were in co-culture with fibroblasts we observed significant increases in the level of matrix deposition which could be reduced by transforming growth factor beta (TGF-β blockade. Our results highlight the role of epithelial cells acting as efficient producers of stable extracellular matrix which could contribute to renal tubule thickening in fibrosis.

Ultrasound-responsive gene-activated matrices for osteogenic gene therapy using matrix-assisted sonoporation.

Science.gov (United States)

Nomikou, N; Feichtinger, G A; Saha, S; Nuernberger, S; Heimel, P; Redl, H; McHale, A P

2018-01-01

Gene-activated matrix (GAM)-based therapeutics for tissue regeneration are limited by efficacy, the lack of spatiotemporal control and availability of target cells, all of which impact negatively on their translation to the clinic. Here, an advanced ultrasound-responsive GAM is described containing target cells that facilitates matrix-assisted sonoporation (MAS) to induce osteogenic differentiation. Ultrasound-responsive GAMs consisting of fibrin/collagen hybrid-matrices containing microbubbles, bone morphogenetic protein BMP2/7 coexpression plasmids together with C2C12 cells were treated with ultrasound either in vitro or following parenteral intramuscular implantation in vivo. Using direct measurement for alkaline phosphatase activity, von Kossa staining and immunohistochemical analysis for osteocalcin expression, MAS-stimulated osteogenic differentiation was confirmed in the GAMs in vitro 7 days after treatment with ultrasound. At day 30 post-treatment with ultrasound, ectopic osteogenic differentiation was confirmed in vivo using X-ray microcomputed tomography and histological analysis. Osteogenic differentiation was indicated by the presence of ectopic bone structures in all animals treated with MAS. In addition, bone volumes in this group were statistically greater than those in the control groups. This novel approach of incorporating a MAS capability into GAMs could be exploited to facilitate ex vivo gene transfer with subsequent surgical implantation or alternatively provide a minimally invasive means of stimulating in situ transgene delivery for osteoinductive gene-based therapies. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

Orbital dynamics of the Anderson--Brinkman--Morel phase of superfluid 3He

International Nuclear Information System (INIS)

Cross, M.C.

1977-01-01

The orbital dynamics of the Anderson--Brinkman--Morel (ABM) phase of helium 3 is studied in both the hydrodynamic and collisionless limits. The complete equations for the orbital motion in the hydrodynamic limit are written down and the important parameters are evaluated by simple arguments. In the collisionless limit the matrix kinetic equation, not including the dipole interaction or Fermi liquid corrections, is inverted exactly to give a form that explicitly displays the various collective modes possible. The existence of an intrinsic orbital angular momentum density of order rho/sub s/h (T/sub c//E/sub f/) 2 and the ''moment of intertia'' term suggested by Leggett and Takagi is confirmed, and a physical understanding of their origin is given. However, in both collisionless and hydrodynamic limits the interaction with the normal fluid dominates the motion except very near zero temperature

Response matrix method for neutron transport in reactor lattices using group symmetry properties

International Nuclear Information System (INIS)

Mund, E.H.

1991-01-01

This paper describes a response matrix method for the approximate solution of one-velocity, multi-dimensional transport problems in reactor lattices, with isotropic neutron scattering. The transport equation is solved on a homogeneous cell by using a Petrov-Galerkin technique based on a set of trial and test functions (including polynomials and exponential functions) closely related to transport problems in infinite media. The number of non-zero elements of the response matrices reduces to a minimum when the symmetry properties of the cell are included ab initio in the span of the basis functions. To include these properties, use is made of projection operations which are performed very efficiently on symbolic manipulation programs. Numerical results of model problems in square geometry show a good agreement with reference solutions

The response matrix discrete ordinates solution to the 1D radiative transfer equation

International Nuclear Information System (INIS)

Ganapol, Barry D.

2015-01-01

The discrete ordinates method (DOM) of solution to the 1D radiative transfer equation has been an effective method of solution for nearly 70 years. During that time, the method has experienced numerous improvements as numerical and computational techniques have become more powerful and efficient. Here, we again consider the analytical solution to the discrete radiative transfer equation in a homogeneous medium by proposing a new, and consistent, form of solution that improves upon previous forms. Aided by a Wynn-epsilon convergence acceleration, its numerical evaluation can achieve extreme precision as demonstrated by comparison with published benchmarks. Finally, we readily extend the solution to a heterogeneous medium through the star product formulation producing a novel benchmark for closed form Henyey–Greenstein scattering as an example. - Highlights: • Presents a new solution to the RTE called the response matrix DOM (RM/DOM). • Solution representations avoid the instability common in exponential solutions. • Explicit form in terms of matrix hyperbolic functions. • Extreme accuracy through Wynn-epsilon acceleration checked by published benchmarks. • Provides a more transparent numerical evaluation than found previously

Reactor calculation in coarse mesh by finite element method applied to matrix response method

International Nuclear Information System (INIS)

Nakata, H.

1982-01-01

The finite element method is applied to the solution of the modified formulation of the matrix-response method aiming to do reactor calculations in coarse mesh. Good results are obtained with a short running time. The method is applicable to problems where the heterogeneity is predominant and to problems of evolution in coarse meshes where the burnup is variable in one same coarse mesh, making the cross section vary spatially with the evolution. (E.G.) [pt

Global calculation of PWR reactor core using the two group energy solution by the response matrix method

International Nuclear Information System (INIS)

Conti, C.F.S.; Watson, F.V.

1991-01-01

A computational code to solve a two energy group neutron diffusion problem has been developed base d on the Response Matrix Method. That method solves the global problem of PWR core, without using the cross sections homogenization process, thus it is equivalent to a pontwise core calculation. The present version of the code calculates the response matrices by the first order perturbative method and considers developments on arbitrary order Fourier series for the boundary fluxes and interior fluxes. (author)

Universal relations for spin-orbit-coupled Fermi gas near an s -wave resonance

Science.gov (United States)

Zhang, Pengfei; Sun, Ning

2018-04-01

Synthetic spin-orbit-coupled quantum gases have been widely studied both experimentally and theoretically in the past decade. As shown in previous studies, this modification of single-body dispersion will in general couple different partial waves of the two-body scattering and thus distort the wave function of few-body bound states which determines the short-distance behavior of many-body wave function. In this work, we focus on the two-component Fermi gas with one-dimensional or three-dimensional spin-orbit coupling (SOC) near an s -wave resonance. Using the method of effective field theory and the operator product expansion, we derive universal relations for both systems, including the adiabatic theorem, viral theorem, and pressure relation, and obtain the momentum distribution matrix 〈ψa†(q ) ψb(q ) 〉 at large q (a ,b are spin indices). The momentum distribution matrix shows both spin-dependent and spatial anisotropic features. And the large momentum tail is modified at the subleading order thanks to the SOC. We also discuss the experimental implication of these results depending on the realization of the SOC.

Mean Orbital Elements for Geosynchronous Orbit - II - Orbital inclination, longitude of ascending node, mean longitude

Directory of Open Access Journals (Sweden)

Kyu-Hong Choi

1990-06-01

Full Text Available The osculating orbital elements include the mean, secular, long period, and short period terms. The iterative algorithm used for conversion of osculating orbital elements to mean orbital elements is described. The mean orbital elements of Wc, Ws, and L are obtained.

Orbital-dependent exchange-correlation functionals in density-functional theory realized by the FLAPW method

Energy Technology Data Exchange (ETDEWEB)

Betzinger, Markus

2011-12-14

In this thesis, we extended the applicability of the full-potential linearized augmented-plane-wave (FLAPW) method, one of the most precise, versatile and generally applicable electronic structure methods for solids working within the framework of density-functional theory (DFT), to orbital-dependent functionals for the exchange-correlation (xc) energy. Two different schemes that deal with orbital-dependent functionals, the Kohn-Sham (KS) and the generalized Kohn-Sham (gKS) formalism, have been realized. Hybrid functionals, combining some amount of the orbital-dependent exact exchange energy with local or semi-local functionals of the density, are implemented within the gKS scheme. We work in particular with the PBE0 hybrid of Perdew, Burke, and Ernzerhof. Our implementation relies on a representation of the non-local exact exchange potential - its calculation constitutes the most time consuming step in a practical calculation - by an auxiliary mixed product basis (MPB). In this way, the matrix elements of the Hamiltonian corresponding to the non-local potential become a Brillouin-zone (BZ) sum over vector-matrix-vector products. Several techniques are developed and explored to further accelerate our numerical scheme. We show PBE0 results for a variety of semiconductors and insulators. In comparison with experiment, the PBE0 functional leads to improved band gaps and an improved description of localized states. Even for the ferromagnetic semiconductor EuO with localized 4f electrons, the electronic and magnetic properties are correctly described by the PBE0 functional. Subsequently, we discuss the construction of the local, multiplicative exact exchange (EXX) potential from the non-local, orbital-dependent exact exchange energy. For this purpose we employ the optimized effective potential (OEP) method. Central ingredients of the OEP equation are the KS wave-function response and the single-particle density response function. We show that a balance between the LAPW

Orbital-dependent exchange-correlation functionals in density-functional theory realized by the FLAPW method

International Nuclear Information System (INIS)

Betzinger, Markus

2011-01-01

In this thesis, we extended the applicability of the full-potential linearized augmented-plane-wave (FLAPW) method, one of the most precise, versatile and generally applicable electronic structure methods for solids working within the framework of density-functional theory (DFT), to orbital-dependent functionals for the exchange-correlation (xc) energy. Two different schemes that deal with orbital-dependent functionals, the Kohn-Sham (KS) and the generalized Kohn-Sham (gKS) formalism, have been realized. Hybrid functionals, combining some amount of the orbital-dependent exact exchange energy with local or semi-local functionals of the density, are implemented within the gKS scheme. We work in particular with the PBE0 hybrid of Perdew, Burke, and Ernzerhof. Our implementation relies on a representation of the non-local exact exchange potential - its calculation constitutes the most time consuming step in a practical calculation - by an auxiliary mixed product basis (MPB). In this way, the matrix elements of the Hamiltonian corresponding to the non-local potential become a Brillouin-zone (BZ) sum over vector-matrix-vector products. Several techniques are developed and explored to further accelerate our numerical scheme. We show PBE0 results for a variety of semiconductors and insulators. In comparison with experiment, the PBE0 functional leads to improved band gaps and an improved description of localized states. Even for the ferromagnetic semiconductor EuO with localized 4f electrons, the electronic and magnetic properties are correctly described by the PBE0 functional. Subsequently, we discuss the construction of the local, multiplicative exact exchange (EXX) potential from the non-local, orbital-dependent exact exchange energy. For this purpose we employ the optimized effective potential (OEP) method. Central ingredients of the OEP equation are the KS wave-function response and the single-particle density response function. We show that a balance between the LAPW

Test of the periodic-orbit approximation in n-disk systems

International Nuclear Information System (INIS)

Wirzba, A.

1993-01-01

The scattering of a point particle in two dimensions from two (or three) equally-sized (and spaced) circular hard disks is one of the simplest classically hyperbolic scattering problems. Because of this simplicity such systems are well suited for the study of the semiclassical periodic-orbit approximation in the cycle expansion of the dynamical zeta function applied to a quantum-mechanical scattering problem. Especially the predictions of the semiclassical cycle expansion for the quantum-mechanical resonances can be tested in these n-disk systems. Whereas for high wave numbers the cycle expansion gives quite accurate results, there are systematic deviations for low wave numbers from the exact quantum-mechanical values. The low-lying quantum-mechanical resonance poles of the 2- and 3-disk problem are constructed and compared to the cycle-expansion results. The characteristic determinant of the scattering matrix is expanded in terms of simple traces which in turn are related to the classical periodic orbits and possible creeping contributions. It will be shown that for large separations of the disks the correct resonance-pole positions can be extracted just from the knowledge of the lowest traces whose semiclassical limit are the fundamental periodic orbits. Creeping-orbit corrections are shown to be small. (orig.)

Critical homoclinic orbits lead to snap-back repellers

International Nuclear Information System (INIS)

Gardini, Laura; Sushko, Iryna; Avrutin, Viktor; Schanz, Michael

2011-01-01

Highlights: → We consider critical homoclinic orbits in continuous and discontinuous maps. → Unbounded homoclinic orbits in maps on unbounded domains are considered as well. → We show that a snapback-repeller (SBR) with a non-critical homoclinic orbit implies chaos. → We show also that a SBR with a critical homoclinic orbit may or may not imply chaos. - Abstract: When nondegenerate homoclinic orbits to an expanding fixed point of a map f:X→X,X subset or equal R n , exist, the point is called a snap-back repeller. It is known that the relevance of a snap-back repeller (in its original definition) is due to the fact that it implies the existence of an invariant set on which the map is chaotic. However, when does the first homoclinic orbit appear? When can other homoclinic explosions, i.e., appearance of infinitely many new homoclinic orbits, occur? As noticed by many authors, these problems are still open. In this work we characterize these bifurcations, for any kind of map, smooth or piecewise smooth, continuous or discontinuous, defined in a bounded or unbounded closed set. We define a noncritical homoclinic orbit and a homoclinic orbit of an expanding fixed point is structurally stable iff it is noncritical. That is, only critical homoclinic orbits are responsible for the homoclinic explosions. The possible kinds of critical homoclinic orbits will be also investigated, as well as their dynamic role.

The role of singular values of measured frequency response function matrix in modal damping estimation (Part I: Theory)

OpenAIRE

Pápai, Ferenc; Szűcs, István

2015-01-01

The singular value decomposition of the measured frequency response function matrix, as a very effective tool of experimental modal analysis is used over the last twenty-five years. The complex mode indication function has become a common numerical tool in processing experimental data. There are many references on the development of complex mode indication function including the enhanced mode indication function and its use together with the enhanced frequency response function to form spatia...

The role of singular values of measured frequency response function matrix in modal damping estimation (Part II: Investigations)

OpenAIRE

Pápai, Ferenc; Szűcs, István

2015-01-01

The singular value decomposition of the measured frequency response function matrix, as a very effective tool of experimental modal analysis is used over the last twenty-five years. The complex mode indication function has become a common numerical tool in processing experimental data. There are many references on the development of complex mode indication function including the enhanced mode indication function and its use together with the enhanced frequency response function to form spatia...

[Orbital inflammation].

Science.gov (United States)

Mouriaux, F; Coffin-Pichonnet, S; Robert, P-Y; Abad, S; Martin-Silva, N

2014-12-01

Orbital inflammation is a generic term encompassing inflammatory pathologies affecting all structures within the orbit : anterior (involvement up to the posterior aspect of the globe), diffuse (involvement of intra- and/or extraconal fat), apical (involvement of the posterior orbit), myositis (involvement of only the extraocular muscles), dacryoadenitis (involvement of the lacrimal gland). We distinguish between specific inflammation and non-specific inflammation, commonly referred to as idiopathic inflammation. Specific orbital inflammation corresponds to a secondary localization of a "generalized" disease (systemic or auto-immune). Idiopathic orbital inflammation corresponds to uniquely orbital inflammation without generalized disease, and thus an unknown etiology. At the top of the differential diagnosis for specific or idiopathic orbital inflammation are malignant tumors, represented most commonly in the adult by lympho-proliferative syndromes and metastases. Treatment of specific orbital inflammation begins with treatment of the underlying disease. For idiopathic orbital inflammation, treatment (most often corticosteroids) is indicated above all in cases of visual loss due to optic neuropathy, in the presence of pain or oculomotor palsy. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

PyORBIT: A Python Shell For ORBIT

Energy Technology Data Exchange (ETDEWEB)

Jean-Francois Ostiguy; Jeffrey Holmes

2003-07-01

ORBIT is code developed at SNS to simulate beam dynamics in accumulation rings and synchrotrons. The code is structured as a collection of external C++ modules for SuperCode, a high level interpreter shell developed at LLNL in the early 1990s. SuperCode is no longer actively supported and there has for some time been interest in replacing it by a modern scripting language, while preserving the feel of the original ORBIT program. In this paper, we describe a new version of ORBIT where the role of SuperCode is assumed by Python, a free, well-documented and widely supported object-oriented scripting language. We also compare PyORBIT to ORBIT from the standpoint of features, performance and future expandability.

PyORBIT: A Python Shell For ORBIT

International Nuclear Information System (INIS)

Jean-Francois Ostiguy; Jeffrey Holmes

2003-01-01

ORBIT is code developed at SNS to simulate beam dynamics in accumulation rings and synchrotrons. The code is structured as a collection of external C++ modules for SuperCode, a high level interpreter shell developed at LLNL in the early 1990s. SuperCode is no longer actively supported and there has for some time been interest in replacing it by a modern scripting language, while preserving the feel of the original ORBIT program. In this paper, we describe a new version of ORBIT where the role of SuperCode is assumed by Python, a free, well-documented and widely supported object-oriented scripting language. We also compare PyORBIT to ORBIT from the standpoint of features, performance and future expandability

Extracellular matrix component signaling in cancer

DEFF Research Database (Denmark)

Multhaupt, Hinke A. B.; Leitinger, Birgit; Gullberg, Donald

2016-01-01

Cell responses to the extracellular matrix depend on specific signaling events. These are important from early development, through differentiation and tissue homeostasis, immune surveillance, and disease pathogenesis. Signaling not only regulates cell adhesion cytoskeletal organization and motil...... as well as matrix constitution and protein crosslinking. Here we summarize roles of the three major matrix receptor types, with emphasis on how they function in tumor progression. [on SciFinder(R)]...

LABAN-PEL: a two-dimensional, multigroup diffusion, high-order response matrix code

International Nuclear Information System (INIS)

Mueller, E.Z.

1991-06-01

The capabilities of LABAN-PEL is described. LABAN-PEL is a modified version of the two-dimensional, high-order response matrix code, LABAN, written by Lindahl. The new version extends the capabilities of the original code with regard to the treatment of neutron migration by including an option to utilize full group-to-group diffusion coefficient matrices. In addition, the code has been converted from single to double precision and the necessary routines added to activate its multigroup capability. The coding has also been converted to standard FORTRAN-77 to enhance the portability of the code. Details regarding the input data requirements and calculational options of LABAN-PEL are provided. 13 refs

The matrix-elements of two-particle residual interaction in the shell-model formalism with the M.S.D.I. approximation. Part 2

International Nuclear Information System (INIS)

Jasielska, A.; Wiktor, S.

1977-01-01

The table of two-particle matrix elements calculated according to the formalism of MSDI approximation for the orbits 1fsub(7/2), 2psub(3/2), 2psub(1/2) and 1fsub(5/2) and published previously is now supplemented by inclusion of the 1gsub(9/2) orbit. (author)

A matrix S for all simple current extensions

International Nuclear Information System (INIS)

Fuchs, J.; Schellekens, A.N.; Schweigert, C.

1996-01-01

A formula is presented for the modular transformation matrix S for any simple current extension of the chiral algebra of a conformal field theory. This provides in particular an algorithm for resolving arbitrary simple current fixed points, in such a way that the matrix S we obtain is unitary and symmetric and furnishes a modular group representation. The formalism works in principle for any conformal field theory. A crucial ingredient is a set of matrices S ab J , where J is a simple current and a and b are fixed points of J. We expect that these input matrices realize the modular group for the torus one-point functions of the simple currents. In the case of WZW-models these matrices can be identified with the S-matrices of the orbit Lie algebras that were introduced recently. As a special case of our conjecture we obtain the modular matrix S for WZW-theories based on group manifolds that are not simply connected, as well as for most coset models. (orig.)

Orbit Propagation and Determination of Low Earth Orbit Satellites

Directory of Open Access Journals (Sweden)

Ho-Nien Shou

2014-01-01

Full Text Available This paper represents orbit propagation and determination of low Earth orbit (LEO satellites. Satellite global positioning system (GPS configured receiver provides position and velocity measures by navigating filter to get the coordinates of the orbit propagation (OP. The main contradictions in real-time orbit which is determined by the problem are orbit positioning accuracy and the amount of calculating two indicators. This paper is dedicated to solving the problem of tradeoffs. To plan to use a nonlinear filtering method for immediate orbit tasks requires more precise satellite orbit state parameters in a short time. Although the traditional extended Kalman filter (EKF method is widely used, its linear approximation of the drawbacks in dealing with nonlinear problems was especially evident, without compromising Kalman filter (unscented Kalman Filter, UKF. As a new nonlinear estimation method, it is measured at the estimated measurements on more and more applications. This paper will be the first study on UKF microsatellites in LEO orbit in real time, trying to explore the real-time precision orbit determination techniques. Through the preliminary simulation results, they show that, based on orbit mission requirements and conditions using UKF, they can satisfy the positioning accuracy and compute two indicators.

Rehabilitation of orbital cavity after orbital exenteration using polymethyl methacrylate orbital prosthesis

Directory of Open Access Journals (Sweden)

Sumeet Jain

2016-01-01

Full Text Available Squamous cell carcinoma of the eyelid is the second most common malignant neoplasm of the eye with the incidence of 0.09 and 2.42 cases/100 000 people. Orbital invasion is a rare complication but, if recognized early, can be treated effectively with exenteration. Although with advancements in technology such as computer-aided design and computer-aided manufacturing, material science, and retentive methods like implants, orbital prosthesis with stock ocular prosthesis made of methyl methacrylate retained by anatomic undercuts is quiet effective and should not be overlooked and forgotten. This clinical report describes prosthetic rehabilitation of two male patients with polymethyl methacrylate resin orbital prosthesis after orbital exenteration, for squamous cell carcinoma of the upper eyelid. The orbital prosthesis was sufficiently retained by hard and soft tissue undercuts without any complications. The patients using the prosthesis are quite satisfied with the cosmetic results and felt comfortable attending the social events.

Supervoltage orbital radiotherapy for progressive Graves' ophthalmopathy

International Nuclear Information System (INIS)

Kriss, J.P.; McDougall, I.R.; Petersen, I.A.; Donaldson, S.S.

1989-01-01

Since 1968 we have employed supervoltage orbital radiation as treatment for severe progressive Graves' ophthalmopathy. A numerical ophthalmic index was used to asess pre- and post-treatment serverity. In the past 20 years we have treated 311 patients of whom 275 have been followed for ≤ 1 year or until any eye surgery was performed. An orbital radiation dosage of 2000 rads in 2 weeks was used for the majority of patients (Series I and III). Series II patients received an orbital dose of 3000 rads in 3 weeks. Demographic differences were observed between these series, thus mandating presentation of the results of each separately. Analyses excluded any result achieved by any post-radiation surgical procedure on the eyes. Post-theraphy worsening of ophtalmopathy occurred in only 29 of 1025 observations. Improvement or complete resolution was observed within each category of eye involvement, but lack of favorable response was also recorded in significant numbers. Improvement in proptosis occurred with the lowest frequency and magnitude. About 30% of the patients required eye muscle surgery to correct residual diplopia. Analysis of the data by step-wise linear regression analysis enabled us a. to derive formulae predicting the problable response to radiation therapy according to sign and severity, and b. identify parameters which diminished the likelihood or the extent of a favorable response. The latter included male sex, never thyrotoxic, age greater than 60 years, and requirement for concomitant treatment for hyperthyroidism. No long-term adverse reactions attributable to the radiotherapy have been observed. We conclude that supervoltage orbital radiotherapy, combined with later eye muscle surgery if necessary, is an effective treatment strategy for progressive Graves' ophthalmopathy. (author)

Orbital

OpenAIRE

Yourshaw, Matthew Stephen

2017-01-01

Orbital is a virtual reality gaming experience designed to explore the use of traditional narrative structure to enhance immersion in virtual reality. The story structure of Orbital was developed based on the developmental steps of 'The Hero's Journey,' a narrative pattern identified by Joseph Campbell. Using this standard narrative pattern, Orbital is capable of immersing the player quickly and completely for the entirety of play time. MFA

Orbit Functions

Directory of Open Access Journals (Sweden)

Anatoliy Klimyk

2006-01-01

Full Text Available In the paper, properties of orbit functions are reviewed and further developed. Orbit functions on the Euclidean space E_n are symmetrized exponential functions. The symmetrization is fulfilled by a Weyl group corresponding to a Coxeter-Dynkin diagram. Properties of such functions will be described. An orbit function is the contribution to an irreducible character of a compact semisimple Lie group G of rank n from one of its Weyl group orbits. It is shown that values of orbit functions are repeated on copies of the fundamental domain F of the affine Weyl group (determined by the initial Weyl group in the entire Euclidean space E_n. Orbit functions are solutions of the corresponding Laplace equation in E_n, satisfying the Neumann condition on the boundary of F. Orbit functions determine a symmetrized Fourier transform and a transform on a finite set of points.

Response of energetic particles to local magnetic dipolarization inside geosynchronous orbit

Science.gov (United States)

Motoba, T.; Ohtani, S.; Gkioulidou, M.; Takahashi, K.

2017-12-01

Magnetic field dipolarization and energetic particle injections are the most distinct phenomena observed in the inner magnetosphere during the substorm expansion phase. Compared to a wealth of knowledge about the phenomenology of magnetic dipolarizations and particle injections at/outside geosynchronous orbit (GEO), our understanding of them inside GEO remains incomplete because of a very limited number of previous studies. In the present study, we statistically examine the response of 1-1000 keV energetic particles to local magnetic dipolarization by performing a superposed epoch analysis of energetic particle fluxes with the zero epoch defined as the dipolarization onset times. Based on data from the Van Allen Probes tail seasons in 2012-2016, we identified a total of 97 magnetic dipolarization events which occurred closer to the magnetic equator (i.e., BH, which is antiparallel to the Earth's dipole axis, is the dominant component of the local magnetic field at least for 5 min before the onset). For major ion species (hydrogen, helium, and oxygen ions), the relative flux intensity to the pre-onset level increases at > 50 keV and decreases at inverse energy dispersion. For dipolarizations with strong impulsive westward electric fields, the relative electron flux intensity increases up to 5-10 times, in particular most significant at several tens of keV. This result suggests that the impulsive electric field acts as an efficient factor in the rapid energization of the tens-of-keV electrons. We also discuss how the response of energetic particles to dipolarization depends on MLT, radial distance, and pitch angle.

Photoionization cross-section for atomic orbitals with random and fixed spatial orientation

International Nuclear Information System (INIS)

Goldberg, S.M.; Fadley, C.S.; Kono, S.

1981-01-01

Atomic photoionization subshell cross-sections and asymmetry parameters necessary for determining the differential cross-sections of randomly-oriented atoms have been calculated within the one-electron, central-potential model and the dipole approximation for all subshells of C, O, Al, Si, S, Ni, Cu, Ga, Ge, As, Se, In, Sb, Cs, Ba, Ce, Ta, W, Pt, Au, and Pb for a photon energy range from 20 to 1500 eV, and the relevant Cooper minima located to within 10 eV. These values are tabulated for general use, together with the associated radial matrix elements and phase shifts. Differential photoionization cross-sections for fixed-orientation s-, p- and d-orbitals have also been derived within the same model for a completely general experimental geometry, and closed-form expressions depending on radial matrix elements and phase shifts are given. For the special geometry of a polarized excitation source with polarization parallel to the electron emission direction, it is further shown that such oriented-atom cross-sections are exactly proportional to the probability distribution of the initial orbital, a result equivalent to that derived by using a plane-wave final-state approximation. However, detailed numerical calculations of cross-sections for oriented Cu 3d and O 2p orbitals in various general geometries and at various energies exhibit significant differences in comparison to plane-wave cross-sections. By contrast, certain prior angular-resolved X-ray photoemission studies of single-crystal valence bands are found to have been carried out in an experimental geometry that fortuitously gave cross-sections close to the plane-wave predictions. (orig.)

Effect of Matrix-Wellbore Flow and Porosity on Pressure Transient Response in Shale Formation Modeling by Dual Porosity and Dual Permeability System

Directory of Open Access Journals (Sweden)

Daolun Li

2015-01-01

Full Text Available A mathematical dual porosity and dual permeability numerical model based on perpendicular bisection (PEBI grid is developed to describe gas flow behaviors in shale-gas reservoirs by incorporating slippage corrected permeability and adsorbed gas effect. Parametric studies are conducted for a horizontal well with multiple infinite conductivity hydraulic fractures in shale-gas reservoir to investigate effect of matrix-wellbore flow, natural fracture porosity, and matrix porosity. We find that the ratio of fracture permeability to matrix permeability approximately decides the bottom hole pressure (BHP error caused by omitting the flow between matrix and wellbore and that the effect of matrix porosity on BHP is related to adsorption gas content. When adsorbed gas accounts for large proportion of the total gas storage in shale formation, matrix porosity only has a very small effect on BHP. Otherwise, it has obvious influence. This paper can help us understand the complex pressure transient response due to existence of the adsorbed gas and help petroleum engineers to interpret the field data better.

Matrix elements of the potential energy operator for the six nucleon system between the generating invariants

International Nuclear Information System (INIS)

Filippov, G.F.; Lopez Trujillo, A.; Rybkin, I.Yu.

1993-01-01

The matrix elements of the potential energy operator (which includes central, spin-orbit and tensor components) are calculated between the generating invariants of the cluster basis describing α + d and t+h configurations of the six-nucleon system. (author). 12 refs

Response matrix of an extended range Bonner sphere spectrometer for the characterization of collimated neutron beams

International Nuclear Information System (INIS)

Bedogni, R.; Esposito, A.; Gomez-Ros, J.M.

2010-01-01

Accelerator-based neutron beams are becoming popular tools for material testing, radiation hardness and soft errors studies. The characterization of these beams in terms of dosimetric and spectrometric quantities is a challenging task, mainly due to their wide energy interval (from thermal up to hundreds MeV) and, in certain facilities like VESUVIO - ISIS (RAL, UK), to their small dimension (few cm in radius). Extended Range Bonner Sphere Spectrometers (ERBSS) would be a valuable tool, due to their wide energy range, good photon discrimination and possibility to choose among different central detectors according to the intensity, photon component and time structure of the field. Nevertheless, the non-uniform irradiation of the spheres could lead to important systematic errors. With the aim of bringing the advantages of ERBSS into the characterization of collimated beams, a dedicated study was performed using the VESUVIO spallation-based collimated beam at ISIS (Rutherford Appleton Laboratory, Oxford). Here a 3.21 cm radius collimated beam was characterized using a Dysprosium activation foil-based ERBSS whose response matrix was recalculated for this specific beam diameter. Besides the results of the experimental campaign, this paper presents the calculation of the response matrix and its dependence on the beam dimension.

Regularization and computational methods for precise solution of perturbed orbit transfer problems

Science.gov (United States)

Woollands, Robyn Michele

The author has developed a suite of algorithms for solving the perturbed Lambert's problem in celestial mechanics. These algorithms have been implemented as a parallel computation tool that has broad applicability. This tool is composed of four component algorithms and each provides unique benefits for solving a particular type of orbit transfer problem. The first one utilizes a Keplerian solver (a-iteration) for solving the unperturbed Lambert's problem. This algorithm not only provides a "warm start" for solving the perturbed problem but is also used to identify which of several perturbed solvers is best suited for the job. The second algorithm solves the perturbed Lambert's problem using a variant of the modified Chebyshev-Picard iteration initial value solver that solves two-point boundary value problems. This method converges over about one third of an orbit and does not require a Newton-type shooting method and thus no state transition matrix needs to be computed. The third algorithm makes use of regularization of the differential equations through the Kustaanheimo-Stiefel transformation and extends the domain of convergence over which the modified Chebyshev-Picard iteration two-point boundary value solver will converge, from about one third of an orbit to almost a full orbit. This algorithm also does not require a Newton-type shooting method. The fourth algorithm uses the method of particular solutions and the modified Chebyshev-Picard iteration initial value solver to solve the perturbed two-impulse Lambert problem over multiple revolutions. The method of particular solutions is a shooting method but differs from the Newton-type shooting methods in that it does not require integration of the state transition matrix. The mathematical developments that underlie these four algorithms are derived in the chapters of this dissertation. For each of the algorithms, some orbit transfer test cases are included to provide insight on accuracy and efficiency of these

Efficiency criterion for teleportation via channel matrix, measurement matrix and collapsed matrix

Directory of Open Access Journals (Sweden)

Xin-Wei Zha

Full Text Available In this paper, three kinds of coefficient matrixes (channel matrix, measurement matrix, collapsed matrix associated with the pure state for teleportation are presented, the general relation among channel matrix, measurement matrix and collapsed matrix is obtained. In addition, a criterion for judging whether a state can be teleported successfully is given, depending on the relation between the number of parameter of an unknown state and the rank of the collapsed matrix. Keywords: Channel matrix, Measurement matrix, Collapsed matrix, Teleportation

Charge transfer interaction using quasiatomic minimal-basis orbitals in the effective fragment potential method

International Nuclear Information System (INIS)

Xu, Peng; Gordon, Mark S.

2013-01-01

The charge transfer (CT) interaction, the most time-consuming term in the general effective fragment potential method, is made much more computationally efficient. This is accomplished by the projection of the quasiatomic minimal-basis-set orbitals (QUAMBOs) as the atomic basis onto the self-consistent field virtual molecular orbital (MO) space to select a subspace of the full virtual space called the valence virtual space. The diagonalization of the Fock matrix in terms of QUAMBOs recovers the canonical occupied orbitals and, more importantly, gives rise to the valence virtual orbitals (VVOs). The CT energies obtained using VVOs are generally as accurate as those obtained with the full virtual space canonical MOs because the QUAMBOs span the valence part of the virtual space, which can generally be regarded as “chemically important.” The number of QUAMBOs is the same as the number of minimal-basis MOs of a molecule. Therefore, the number of VVOs is significantly smaller than the number of canonical virtual MOs, especially for large atomic basis sets. This leads to a dramatic decrease in the computational cost

Aspects of U-duality in matrix theory

International Nuclear Information System (INIS)

Blau, M.; O'Loughlin, M.

1997-12-01

We explore various aspects of implementing the full M-theory U-duality group E d+1 , and thus Lorentz invariance, in the finite N matrix theory (DLCQ of M-theory) describing toroidal IIA-compactifications on d-tori: (1) We generalize the analysis of Elitzur et al. (hep-th/9707217) from E d to E d+1 and identify the highest weight states unifying the momentum and flux E d -multiplets into one E d+1 -orbit, (2) We identify the new symmetries, in particular the Weyl group symmetry associated to the (d+1)'th node of the E d+1 Dynkin diagram, with Nahm-duality-like symmetries (N-duality) exchanging the rank N of the matrix theory gauge group with other (electric, magnetic, ...) quantum numbers. (3) We describe the action of N-duality on BPS bound states, thus making testable predictions for the Lorentz invariance of matrix theory. (4) We discuss the problems that arise in the matrix theory limit for BPS states with no top-dimensional branes, i.e. configurations with N = 0. (5) We show that N-duality maps the matrix theory SYM picture to the matrix string picture and argue that, for d even, the latter should be thought of as an M-theory membrane description (which appears to be well defined even for d > 5). (6) We find a compact and unified expression for a U-duality invariant of E d+1 for all d and show that in d = 5,6 it reduces to the black hole entropy cubic E 6 - and quartic E 7 -invariants respectively. (7) Finally, we describe some of the solitonic states in d = 6,7 and give an example (a 'rolled-up' Taub-NUT 6-brane) of a configuration exhibiting the unusual 1/g 3 s -behaviour. (author)

Kinetic-energy matrix elements for atomic Hylleraas-CI wave functions

Energy Technology Data Exchange (ETDEWEB)

Harris, Frank E., E-mail: harris@qtp.ufl.edu [Department of Physics, University of Utah, Salt Lake City, Utah 84112, USA and Quantum Theory Project, University of Florida, P.O. Box 118435, Gainesville, Florida 32611 (United States)

2016-05-28

Hylleraas-CI is a superposition-of-configurations method in which each configuration is constructed from a Slater-type orbital (STO) product to which is appended (linearly) at most one interelectron distance r{sub ij}. Computations of the kinetic energy for atoms by this method have been difficult due to the lack of formulas expressing these matrix elements for general angular momentum in terms of overlap and potential-energy integrals. It is shown here that a strategic application of angular-momentum theory, including the use of vector spherical harmonics, enables the reduction of all atomic kinetic-energy integrals to overlap and potential-energy matrix elements. The new formulas are validated by showing that they yield correct results for a large number of integrals published by other investigators.

EPR of some low-spin dsup(5) tris-chelate complexes of Fe(3), Ru(3), Os(3) in liquid-crystal matrix

International Nuclear Information System (INIS)

Domracheva, N.E.; Konstantinov, V.N.; Luchkona, S.A.; Ovchinnikov, I.V.

1985-01-01

Using the EPR method low-spin trischelate complexes of Fe, Ru, Os with 8-mercaptoquinoline and 8-oxyquinoline in oriented vitrified liquid-crystal matrix have been studied. Analtysis of angular dependences of EPR spectra of the complexes permitted to correlate the main axes of g-tensor with molecular axes and, consequently, to determine unambiguously the main electron states of the systems, as well as the value of crystal splittings. It is shown that in the complexes studied the splitting of energy levels is mainly determined by spin-orbital interaction, and not by axial or rhombic components of crystal field. However, rhombic distortion is responsible for anisotropy of g-tensor in xy plane and anisotropy of x- and y-axes orientation. The way to orient complexes in liquid-crystal matrix is substantiated; symmetry axis of the third order C 3 (Z) is mainly oriented along the director. Parameters of the function of orientational distribution of the complex axes are obtained

Adaptive frozen orbital treatment for the fragment molecular orbital method combined with density-functional tight-binding

Science.gov (United States)

Nishimoto, Yoshio; Fedorov, Dmitri G.

2018-02-01

The exactly analytic gradient is derived and implemented for the fragment molecular orbital (FMO) method combined with density-functional tight-binding (DFTB) using adaptive frozen orbitals. The response contributions which arise from freezing detached molecular orbitals on the border between fragments are computed by solving Z-vector equations. The accuracy of the energy, its gradient, and optimized structures is verified on a set of representative inorganic materials and polypeptides. FMO-DFTB is applied to optimize the structure of a silicon nano-wire, and the results are compared to those of density functional theory and experiment. FMO accelerates the DFTB calculation of a boron nitride nano-ring with 7872 atoms by a factor of 406. Molecular dynamics simulations using FMO-DFTB applied to a 10.7 μm chain of boron nitride nano-rings, consisting of about 1.2 × 106 atoms, reveal the rippling and twisting of nano-rings at room temperature.

ERS orbit control

Science.gov (United States)

Rosengren, Mats

1991-12-01

The European remote sensing mission orbit control is addressed. For the commissioning phase, the orbit is defined by the following requirements: Sun synchronous, local time of descending node 10:30; three days repeat cycle with 43 orbital revolutions; overhead Venice tower (12.508206 deg east, 45.314222 deg north). The launch, maneuvers for the initial acquisition of the operational orbit, orbit maintenance maneuvers, evaluation of the orbit control, and the drift of the inclination are summarized.

MUSIC-type imaging of a thin penetrable inclusion from its multi-static response matrix

International Nuclear Information System (INIS)

Park, Won-Kwang; Lesselier, Dominique

2009-01-01

The imaging of a thin inclusion, with dielectric and/or magnetic contrasts with respect to the embedding homogeneous medium, is investigated. A MUSIC-type algorithm operating at a single time-harmonic frequency is developed in order to map the inclusion (that is, to retrieve its supporting curve) from scattered field data collected within the multi-static response matrix. Numerical experiments carried out for several types of inclusions (dielectric and/or magnetic ones, straight or curved ones), mostly single inclusions and also two of them close by as a straightforward extension, illustrate the pros and cons of the proposed imaging method

MUSIC-type imaging of a thin penetrable inclusion from its multi-static response matrix

Science.gov (United States)

Park, Won-Kwang; Lesselier, Dominique

2009-07-01

The imaging of a thin inclusion, with dielectric and/or magnetic contrasts with respect to the embedding homogeneous medium, is investigated. A MUSIC-type algorithm operating at a single time-harmonic frequency is developed in order to map the inclusion (that is, to retrieve its supporting curve) from scattered field data collected within the multi-static response matrix. Numerical experiments carried out for several types of inclusions (dielectric and/or magnetic ones, straight or curved ones), mostly single inclusions and also two of them close by as a straightforward extension, illustrate the pros and cons of the proposed imaging method.

Modelling the response of stable water isotopes in Greenland precipitation to orbital configurations of the previous interglacial

Directory of Open Access Journals (Sweden)

Jesper Sjolte

2014-09-01

Full Text Available The relation between δ 18O of precipitation and temperature has been used in numerous studies to reconstruct past temperatures at ice core sites in Greenland and Antarctica. During the past two decades, it has become clear that the slope between δ 18O and temperature varies in both space and time. Here, we use a general circulation model driven by changes in orbital parameters to investigate the Greenland δ 18O–temperature relation for the previous interglacial, the Eemian. In our analysis, we focus on changes in the moisture source regions, and the results underline the importance of taking the seasonality of climate change into account. The orbitally driven experiments show that continental evaporation over North America increases during summer in the warm parts of the Eemian, while marine evaporation decreases. This likely flattens the Greenland δ 18O response to temperature during summer. Since the main climate change in the experiments occurs during summer this adds to a limited response of δ 18O, which is more strongly tied to temperature during winter than during summer. A south–west to north–east gradient in the δ 18O–temperature slope is also evident for Greenland, with low slopes in the south–west and steeper slopes in the north–east. This probably reflects the proportion of continental moisture and Arctic moisture arriving in Greenland, with more continental moisture in the south–west and less in the north–east, and vice versa for the Arctic moisture.

Radiotherapy of lymphoid diseases of the orbit

International Nuclear Information System (INIS)

Austin-Seymour, M.M.; Donaldson, S.S.; Egbert, P.R.; McDougall, I.R.; Kriss, J.P.

1985-01-01

Thirty-two patients with orbital pseudotumor (18), reactive lymphoid hyperplasia (2), atypical lymphoid infiltrate (4) or malignant lymphoma (8) were treated in the Division of Radiation Therapy at Stanford University between January 1973 and May 1983. Of the 20 patients with pseudotumor or reactive lymphoid hyperplasia, 10 had unilateral lesions and 10 had bilateral lesions. Biopsy samples were obtained in 15 patients; in five patients with bilateral disease the diagnosis was made on the basis of computed tomography (CT) and clinical findings. The majority of patients were referred because of disease refractory to treatment with corticosteroids. The patients were given a mean dose of 2360 rad using complex, individualized megavoltage techniques including lens shielding. Radiotherapy was well tolerated with no significant acute or late complications. Fifteen patients had complete resolution of symptoms after treatment; five had continued symptoms. Of the 12 patients with malignant lymphoma or atypical lymphoid infiltrate, four had systemic lymphoma with orbital involvement and eight had orbital involvement only. A mean dose of 3625 rad was delivered to the orbit only. Most of the patients received complex megavoltage treatment using bolus. All patients in this group had a complete response and local control. Two patients developed cataracts. Carefullly planned orbital radiotherapy provides local control without symptomatic sequelae for orbital masses ranging from pseudotumor to malignant lymphoma

Response of carbon fluxes and climate to orbital forcing changes in the Community Climate System Model

Science.gov (United States)

Jochum, M.; Peacock, S.; Moore, J. K.; Lindsay, K. T.

2009-12-01

A global general circulation model coupled to an ocean ecosystem model is used to quantify the response of carbon fluxes and climate to changes in orbital forcing. Compared to the present-day simulation, the simulation with the Earth's orbital parameters from 115,000 years ago features significantly cooler northern high latitudes, but only moderately cooler southern high latitudes. This asymmetry is explained by a 30% reduction of the strength of the Atlantic Meridional Overturning Circulation that is caused by an increased Arctic sea-ice export and a resulting freshening of the North Atlantic. The strong northern high-latitude cooling and the direct insolation induced tropical warming lead to global shifts in precipitation and winds to the order of 10-20%. These climate shifts lead to regional differences in air-sea carbon fluxes of the same order. However, the differences in global net carbon fluxes are insignificant. This surprising result is due to several effects, two of which stand out: Firstly, colder sea surface temperature leads to a more effective solubility pump but also to increased sea-ice concentration which blocks air-sea exchange; and secondly, the weakening of Southern Ocean winds, which is predicted by some idealized studies, is small compared to its interannual variability.

Effect of Rashba and Dresselhaus Spin-Orbit Couplings on Electron Spin Polarization in a Hybrid Magnetic-Electric Barrier Nanostructure

Science.gov (United States)

Yang, Shi-Peng; Lu, Mao-Wang; Huang, Xin-Hong; Tang, Qiang; Zhou, Yong-Long

2017-04-01

A theoretical study has been carried out on the spin-dependent electron transport in a hybrid magnetic-electric barrier nanostructure with both Rashba and Dresselhaus spin-orbit couplings, which can be experimentally realized by depositing a ferromagnetic strip and a Schottky metal strip on top of a semiconductor heterostructure. The spin-orbit coupling-dependent transmission coefficient, conductance, and spin polarization are calculated by solving the Schrödinger equation exactly with the help of the transfer-matrix method. We find that both the magnitude and sign of the electron spin polarization vary strongly with the spin-orbit coupling strength. Thus, the degree of electron spin polarization can be manipulated by properly adjusting the spin-orbit coupling strength, and such a nanosystem can be employed as a controllable spin filter for spintronics applications.

A Typical Presentation of Orbital Pseudotumor Mimicking Orbital Cellulitis

Directory of Open Access Journals (Sweden)

J. Ayatollahi

2013-10-01

Full Text Available Introduction: Orbital pseudotumor, also known as idiopathic orbital inflammatory syndrome (IOIS, is a benign, non- infective inflammatory condition of the orbit without identifiable local or systemic causes. The disease may mimics a variety of pathologic conditions. We pre-sent a case of pseudotumor observed in a patient admitted under the name of orbital celluli-ties. Case Report: A 26-year-old woman reffered to our hospital with the history of left ocular pain and headache 2 days before her visit.. Ophthalmological examination of the patient was normal except for the redness and lid edema, mild chemosis and conjunctival injection. Gen-eral assessment was normal but a low grade fever was observed. She was hospitalized as an orbital cellulitis patient. She was treated with intravenous antibiotics. On the third day , sud-denly diplopia, proptosis in her left eye and ocular pain in her right side appeared. MRI re-vealed bilateral enlargement of extraocular muscles. Diagnosis of orbital pseudotumor was made and the patient was treated with oral steroid.She responded promptly to the treatment. Antibiotics were discontinued and steroid was tapered in one month period under close fol-low up. Conclusion: The clinical features of orbital pseudotumor vary widely . Orbital pseudotumor and orbital cellulitis can occasionally demonstrate overlapping features.. Despite complete physical examination and appropriate imaging, sometimes correct diagnosis of the disease would be difficult (Sci J Hamadan Univ Med Sci 2013; 20 (3:256-259

Spin alignment and density matrix measurement in 28Si + 12C orbiting reaction

International Nuclear Information System (INIS)

Ray, A.; Shapira, D.; Halbert, M.L.; Gomez del Campo, J.; Kim, H.J.; Sullivan, J.P.; Shivakumar, B.; Mitchell, J.

1990-01-01

Gamma-ray angular correlations have been measured for the strongly damped reactions 12 C( 28 Si, 12 C) 28 Si between θ cm = (120 degree - 160 degree) for E cm = 43.5 and 48 MeV. We find that the density matrices for the 12 C(2 1 + ) and 28 Si states are almost diagonal with respect to the direction of motion of the outgoing particle. The measured density matrices and spin alignments are consistent with the picture of formation of a long-lived dinuclear complex undergoing orbiting, bending and wriggling motions, but not with those obtained from statistical compound nucleus or sticking model calculations. 17 refs., 2 figs., 1 tab

Deadly Sunflower Orbits

Science.gov (United States)

Hamilton, Douglas P.

2018-04-01

Solar radiation pressure is usually very effective at removing hazardous millimeter-sized debris from distant orbits around asteroidsand other small solar system bodies (Hamilton and Burns 1992). Theprimary loss mechanism, driven by the azimuthal component of radiationpressure, is eccentricity growth followed by a forced collision withthe central body. One large class of orbits, however, neatly sidestepsthis fate. Orbits oriented nearly perpendicular to the solar directioncan maintain their face-on geometry, oscillating slowly around a stableequilibrium orbit. These orbits, designated sunflower orbits, arerelated to terminator orbits studied by spacecraft mission designers(Broschart etal. 2014).Destabilization of sunflower orbits occurs only for particles smallenough that radiation pressure is some tens of percent the strength ofthe central body's direct gravity. This greatly enhanced stability,which follows from the inability of radiation incident normal to theorbit to efficiently drive eccentricities, presents a threat tospacecraft missions, as numerous dangerous projectiles are potentiallyretained in orbit. We have investigated sunflower orbits insupport of the New Horizons, Aida, and Lucy missions and find thatthese orbits are stable for hazardous particle sizes at asteroids,comets, and Kuiper belt objects of differing dimensions. Weinvestigate the sources and sinks for debris that might populate suchorbits, estimate timescales and equilibrium populations, and willreport on our findings.

Applying the response matrix method for solving coupled neutron diffusion and transport problems

International Nuclear Information System (INIS)

Sibiya, G.S.

1980-01-01

The numerical determination of the flux and power distribution in the design of large power reactors is quite a time-consuming procedure if the space under consideration is to be subdivided into very fine weshes. Many computing methods applied in reactor physics (such as the finite-difference method) require considerable computing time. In this thesis it is shown that the response matrix method can be successfully used as an alternative approach to solving the two-dimension diffusion equation. Furthermore it is shown that sufficient accuracy of the method is achieved by assuming a linear space dependence of the neutron currents on the boundaries of the geometries defined for the given space. (orig.) [de

Matrix- and plasma-derived peptides promote tissue-specific injury responses and wound healing in diabetic swine.

Science.gov (United States)

Sheets, Anthony R; Massey, Conner J; Cronk, Stephen M; Iafrati, Mark D; Herman, Ira M

2016-07-02

Non-healing wounds are a major global health concern and account for the majority of non-traumatic limb amputations worldwide. However, compared to standard care practices, few advanced therapeutics effectively resolve these injuries stemming from cardiovascular disease, aging, and diabetes-related vasculopathies. While matrix turnover is disrupted in these injuries, debriding enzymes may promote healing by releasing matrix fragments that induce cell migration, proliferation, and morphogenesis, and plasma products may also stimulate these processes. Thus, we created matrix- and plasma-derived peptides, Comb1 and UN3, which induce cellular injury responses in vitro, and accelerate healing in rodent models of non-healing wounds. However, the effects of these peptides in non-healing wounds in diabetes are not known. Here, we interrogated whether these peptides stimulate healing in a diabetic porcine model highly reminiscent of human healing impairments in type 1 and type 2-diabetes. After 3-6 weeks of streptozotocin-induced diabetes, full-thickness wounds were surgically created on the backs of adult female Yorkshire swine under general anesthesia. Comb1 and UN3 peptides or sterile saline (negative control) were administered to wounds daily for 3-7 days. Following sacrifice, wound tissues were harvested, and quantitative histological and immunohistochemical analyses were performed for wound closure, angiogenesis and granulation tissue deposition, along with quantitative molecular analyses of factors critical for angiogenesis, epithelialization, and dermal matrix remodeling. Comb1 and UN3 significantly increase re-epithelialization and angiogenesis in diabetic porcine wounds, compared to saline-treated controls. Additionally, fluorescein-conjugated Comb1 labels keratinocytes, fibroblasts, and vascular endothelial cells in porcine wounds, and Far western blotting reveals these cell populations express multiple fluorescein-Comb1-interacting proteins in vitro. Further

Formulation development and optimization of sustained release matrix tablet of Itopride HCl by response surface methodology and its evaluation of release kinetics.

Science.gov (United States)

Bose, Anirbandeep; Wong, Tin Wui; Singh, Navjot

2013-04-01

The objective of this present investigation was to develop and formulate sustained release (SR) matrix tablets of Itopride HCl, by using different polymer combinations and fillers, to optimize by Central Composite Design response surface methodology for different drug release variables and to evaluate drug release pattern of the optimized product. Sustained release matrix tablets of various combinations were prepared with cellulose-based polymers: hydroxy propyl methyl cellulose (HPMC) and polyvinyl pyrolidine (pvp) and lactose as fillers. Study of pre-compression and post-compression parameters facilitated the screening of a formulation with best characteristics that underwent here optimization study by response surface methodology (Central Composite Design). The optimized tablet was further subjected to scanning electron microscopy to reveal its release pattern. The in vitro study revealed that combining of HPMC K100M (24.65 MG) with pvp(20 mg)and use of LACTOSE as filler sustained the action more than 12 h. The developed sustained release matrix tablet of improved efficacy can perform therapeutically better than a conventional tablet.

Self-consistent embedding of density-matrix renormalization group wavefunctions in a density functional environment.

Science.gov (United States)

Dresselhaus, Thomas; Neugebauer, Johannes; Knecht, Stefan; Keller, Sebastian; Ma, Yingjin; Reiher, Markus

2015-01-28

We present the first implementation of a density matrix renormalization group algorithm embedded in an environment described by density functional theory. The frozen density embedding scheme is used with a freeze-and-thaw strategy for a self-consistent polarization of the orbital-optimized wavefunction and the environmental densities with respect to each other.

[Idiopathic orbital inflammatory syndrome: Report of 24 cases].

Science.gov (United States)

Khochtali, S; Zayani, M; Ksiaa, I; Ben Meriem, I; Zaouali, S; Jelliti, B; Khairallah, M

2018-04-01

Idiopathic orbital inflammatory syndrome (IOIS) is an inflammatory condition of unknown etiology. The inflammation may affect all the structures within the orbit (anterior, diffuse, apical, myositic, dacryoadenitis) and corresponds to uniquely orbital inflammation without an identifiable local cause or systemic disease. The goal of this study is to describe the clinical and radiographic characteristics of IOIS and discuss the role of orbital biopsy in this condition. This is a retrospective review of the charts of 24 patients diagnosed with IOIS at Fattouma Bourguiba hospital, Monastir, Tunisia, from January 2007 to December 2015. This study included all patients with IOIS and a minimum follow-up of six months. All patients had a complete ophthalmological examination and orbital and head CT scan and/or MRI. A work-up was performed in all cases to rule out local causes and systemic disease. Only 11 patients underwent biopsy. The diagnosis of the clinical entity IOIS was made according to the Rootman criteria. Oral steroids were the first line therapy. A bolus of intravenous methylprednisolone was administered first in vision-threatening cases. Response to treatment was defined as disappearance of signs and symptoms of IOIS. Orbital pain was the most common symptom (62.5%), followed by proptosis and decreased vision (37.5% each). Best-corrected visual acuity (BCVA) was greater than 5/10 in 70.7% of patients. Lacrimal gland enlargement was observed in 3 patients. Oculomotor disorders were present in 70% of cases and 20.8% of patients had compressive optic neuropathy. Orbital imaging showed, in most cases, oculomotor muscle inflammation (87.5%) involving particularly the superior rectus muscle (54.2%) and inflammation of orbital fat (66.7%). Fifty percent had myositic inflammation. Biopsy was performed in 11 patients, showing nonspecific inflammation (n=10) and the sclerosing form (n=1). A total of 83.3% of patients received oral corticosteroids for a mean duration of

Orbits

CERN Document Server

Xu, Guochang

2008-01-01

This is the first book of the satellite era which describes orbit theory with analytical solutions of the second order with respect to all possible disturbances. Based on such theory, the algorithms of orbits determination are completely revolutionized.

Decay of autoionizing states in time-dependent density functional and reduced density matrix functional theory

Energy Technology Data Exchange (ETDEWEB)

Kapoor, Varun; Brics, Martins; Bauer, Dieter [Institut fuer Physik, Universitaet Rostock, 18051 Rostock (Germany)

2013-07-01

Autoionizing states are inaccessible to time-dependent density functional theory (TDDFT) using known, adiabatic Kohn-Sham (KS) potentials. We determine the exact KS potential for a numerically exactly solvable model Helium atom interacting with a laser field that is populating an autoionizing state. The exact single-particle density of the population in the autoionizing state corresponds to that of the energetically lowest quasi-stationary state in the exact KS potential. We describe how this exact potential controls the decay by a barrier whose height and width allows for the density to tunnel out and decay with the same rate as in the ab initio time-dependent Schroedinger calculation. However, devising a useful exchange-correlation potential that is capable of governing such a scenario in general and in more complex systems is hopeless. As an improvement over TDDFT, time-dependent reduced density matrix functional theory has been proposed. We are able to obtain for the above described autoionization process the exact time-dependent natural orbitals (i.e., the eigenfunctions of the exact, time-dependent one-body reduced density matrix) and study the potentials that appear in the equations of motion for the natural orbitals and the structure of the two-body density matrix expanded in them.

Orbital Chondroma: A rare mesenchymal tumor of orbit

Directory of Open Access Journals (Sweden)

Ruchi S Kabra

2015-01-01

Full Text Available While relatively common in the skeletal system, cartilaginous tumors are rarely seen originating from the orbit. Here, we report a rare case of an orbital chondroma. A 27-year-old male patient presented with a painless hard mass in the superonasal quadrant (SNQ of left orbit since 3 months. On examination, best-corrected visual acuity of both eyes was 20/20, with normal anterior and posterior segment with full movements of eyeballs and normal intraocular pressure. Computerized tomography scan revealed well defined soft tissue density lesion in SNQ of left orbit. Patient was operated for anteromedial orbitotomy under general anesthesia. Mass was excised intact and sent for histopathological examination (HPE. HPE report showed lobular aggregates of benign cartilaginous cells with mild atypia suggesting of benign cartilaginous tumor - chondroma. Very few cases of orbital chondroma have been reported in literature so far.

Periodic-orbit theory of the number variance Σ2(L) of strongly chaotic systems

International Nuclear Information System (INIS)

Aurich, R.; Steiner, F.

1994-03-01

We discuss the number variance Σ 2 (L) and the spectral form factor F(τ) of the energy levels of bound quantum systems whose classical counterparts are strongly chaotic. Exact periodic-orbit representations of Σ 2 (L) and F(τ) are derived which explain the breakdown of universality, i.e., the deviations from the predictions of random-matrix theory. The relation of the exact spectral form factor F(τ) to the commonly used approximation K(τ) is clarified. As an illustration the periodic-orbit representations are tested in the case of a strongly chaotic system at low and high energies including very long-range correlations up to L=700. Good agreement between 'experimental' data and theory is obtained. (orig.)

Circular orbits in cosmic string and Schwarzschild-AdS spacetime with Fermi-Walker transport

International Nuclear Information System (INIS)

Bakke, K.; Furtado, C.; Carvalho, A.M. de

2009-01-01

In this paper we discuss the Fermi-Walker transport of vectors along orbits in cosmic string and Schwarzschild-AdS spacetimes. We analyze the influence of acceleration on these holonomies. An effect similar to Thomas precession is observed within the process of Fermi-Walker transport along these circular orbits which are studied in the limit of vanishing cosmological constant in Schwarzschild-AdS case; also we obtain Fermi-Walker transport in a Schwarzschild background. In the case of a Schwarzschild spacetime, we analyze the quantized band holonomy invariance. In the limit of zero acceleration we recover the well-known results for holonomy matrix obtained by parallel transport in all these spacetimes. (orig.)

The structure of cell-matrix adhesions: the new frontier.

Science.gov (United States)

Hanein, Dorit; Horwitz, Alan Rick

2012-02-01

Adhesions between the cell and the extracellular matrix (ECM) are mechanosensitive multi-protein assemblies that transmit force across the cell membrane and regulate biochemical signals in response to the chemical and mechanical environment. These combined functions in force transduction, signaling and mechanosensing contribute to cellular phenotypes that span development, homeostasis and disease. These adhesions form, mature and disassemble in response to actin organization and physical forces that originate from endogenous myosin activity or external forces by the extracellular matrix. Despite advances in our understanding of the protein composition, interactions and regulation, our understanding of matrix adhesion structure and organization, how forces affect this organization, and how these changes dictate specific signaling events is limited. Insights across multiple structural levels are acutely needed to elucidate adhesion structure and ultimately the molecular basis of signaling and mechanotransduction. Here we describe the challenges and recent advances and prospects for unraveling the structure of cell-matrix adhesions and their response to force. Copyright © 2011 Elsevier Ltd. All rights reserved.

Theoretical study of spin–orbit and Coriolis coupling among the low-lying states of Rb{sub 2} and Cs{sub 2}

Energy Technology Data Exchange (ETDEWEB)

Pazyuk, Elena A.; Revina, Elena I.; Stolyarov, Andrey V., E-mail: avstol@phys.chem.msu.ru

2015-11-25

Highlights: • Spin–orbit and angular coupling matrix elements of Rb{sub 2} and Cs{sub 2} were ab initio calculated. • The predicted molecular parameters agree well with the most experimental counterparts. • Non-adiabatic treatment of Rb{sub 2} and Cs{sub 2} properties could be accomplished with high accuracy. - Abstract: The spin–orbit (SO) and angular (Coriolis) coupling matrix elements of rubidium and cesium dimers have been calculated between the states converging to the lowest three dissociation limits. The relevant quasi-relativistic matrix elements were evaluated for a wide range of internuclear distances and density grid in the basis of the spin-averaged wave functions corresponding to pure Hund’s coupling case (a). Both shape and energy consistent small (9-electrons) effective core pseudopotentials were used to monitor a sensitivity of the matrix elements to the particular basis set. The dynamic correlation has been taken accounted by a large scale multi-reference configuration interaction method which was applied for only two valence electrons. The l-independent core-polarization potentials were employed to take into account the residual core-valence effect. The assessment of current accuracy of the present ab initio functions is discussed by a comparison with preceding calculations and their empirical counterparts.

Development of spectral history methods for pin-by-pin core analysis method using three-dimensional direct response matrix

International Nuclear Information System (INIS)

Mitsuyasu, T.; Ishii, K.; Hino, T.; Aoyama, M.

2009-01-01

Spectral history methods for pin-by-pin core analysis method using the three-dimensional direct response matrix have been developed. The direct response matrix is formalized by four sub-response matrices in order to respond to a core eigenvalue k and thus can be recomposed at each outer iteration in the core analysis. For core analysis, it is necessary to take into account the burn-up effect related to spectral history. One of the methods is to evaluate the nodal burn-up spectrum obtained using the out-going neutron current. The other is to correct the fuel rod neutron production rates obtained the pin-by-pin correction. These spectral history methods were tested in a heterogeneous system. The test results show that the neutron multiplication factor error can be reduced by half during burn-up, the nodal neutron production rates errors can be reduced by 30% or more. The root-mean-square differences between the relative fuel rod neutron production rate distributions can be reduced within 1.1% error. This means that these methods can accurately reflect the effects of intra- and inter-assembly heterogeneities during burn-up and can be used for core analysis. Core analysis with the DRM method was carried out for an ABWR quarter core and it was found that both thermal power and coolant-flow distributions were smoothly converged. (authors)

Local orbitals by minimizing powers of the orbital variance

DEFF Research Database (Denmark)

Jansik, Branislav; Høst, Stinne; Kristensen, Kasper

2011-01-01

's correlation consistent basis sets, it is seen that for larger penalties, the virtual orbitals become more local than the occupied ones. We also show that the local virtual HF orbitals are significantly more local than the redundant projected atomic orbitals, which often have been used to span the virtual...

One year in orbit of the first Geostationary Ocean Colour Imager (GOCI)

Science.gov (United States)

Faure, François; Coste, Pierre; Benchetrit, Thierry; Kang, Gm Sil; Kim, Han-dol

2017-11-01

Geostationary Ocean Colour Imager (GOCI) is the first Ocean Colour Imager to operate from a Geostationary Orbit. It was developed by Astrium SAS under KARI contract in about 3 years between mid 2005 and October 2008 and integrated on-board COMS satellite end 2008 aside the COMS Meteo Imager (MI). COMS satellite was launched in June 2010 and the in-orbit commissioning tests were completed in beginning of 2011. The mission is designed to significantly improve ocean observation in complement with low orbit service by providing high frequency coverage. The GOCI is designed to provide multi-spectral data to detect, monitor, quantify, and predict short-term changes of coastal ocean environment for marine science research and application purpose. Target area for the GOCI observation in the COMS satellite covers a large 2500 x 2500 km2 sea area around the Korean Peninsula, with an average Ground sampling distance (GSD) of 500m, corresponding to a NADIR GSD of 360m. The presentation will shortly recall the mission objectives and major instrument requirements, and then present the results of inorbit testing and validations. All functions and in particular the CMOS detector matrix operate nominally. Performances evaluated in orbit (SNR, MTF, etc.) show results above the requirements. Finally, in-orbit calibrations using the sun diffuser provide very satisfactory consistency with the ground characterisation. GOCI is now delivering operational products and proving the interest of Geo observation in the Ocean Colour applications

Key role of orbital anisotropy in geometrically frustrated electron system

International Nuclear Information System (INIS)

Onishi, Hiroaki; Hotta, Takashi

2005-01-01

By using the density matrix renormalization group method, we investigate ground- and excited-state properties of the e g -orbital degenerate Hubbard model at quarter filling for two kinds of lattices, zigzag chain and ladder. In the zigzag chain, the system is effectively regarded as a decoupled double chain of the S=12 antiferromagnetic Heisenberg model, and the spin gap is approximately zero, similar to the case of weakly coupled Heisenberg chains. On the other hand, in the ladder, the spin correlation on the rung remains robust and the spin gap exists

A self-consistent nodal method in response matrix formalism for the multigroup diffusion equations

International Nuclear Information System (INIS)

Malambu, E.M.; Mund, E.H.

1996-01-01

We develop a nodal method for the multigroup diffusion equations, based on the transverse integration procedure (TIP). The efficiency of the method rests upon the convergence properties of a high-order multidimensional nodal expansion and upon numerical implementation aspects. The discrete 1D equations are cast in response matrix formalism. The derivation of the transverse leakage moments is self-consistent i.e. does not require additional assumptions. An outstanding feature of the method lies in the linear spatial shape of the local transverse leakage for the first-order scheme. The method is described in the two-dimensional case. The method is validated on some classical benchmark problems. (author)

Price elasticity matrix of demand in power system considering demand response programs

Science.gov (United States)

Qu, Xinyao; Hui, Hongxun; Yang, Shengchun; Li, Yaping; Ding, Yi

2018-02-01

The increasing renewable energy power generations have brought more intermittency and volatility to the electric power system. Demand-side resources can improve the consumption of renewable energy by demand response (DR), which becomes one of the important means to improve the reliability of power system. In price-based DR, the sensitivity analysis of customer’s power demand to the changing electricity prices is pivotal for setting reasonable prices and forecasting loads of power system. This paper studies the price elasticity matrix of demand (PEMD). An improved PEMD model is proposed based on elasticity effect weight, which can unify the rigid loads and flexible loads. Moreover, the structure of PEMD, which is decided by price policies and load types, and the calculation method of PEMD are also proposed. Several cases are studied to prove the effectiveness of this method.

A response matrix method for one-speed discrete ordinates fixed source problems in slab geometry with no spatial truncation error

International Nuclear Information System (INIS)

Lydia, Emilio J.; Barros, Ricardo C.

2011-01-01

In this paper we describe a response matrix method for one-speed slab-geometry discrete ordinates (SN) neutral particle transport problems that is completely free from spatial truncation errors. The unknowns in the method are the cell-edge angular fluxes of particles. The numerical results generated for these quantities are exactly those obtained from the analytic solution of the SN problem apart from finite arithmetic considerations. Our method is based on a spectral analysis that we perform in the SN equations with scattering inside a discretization cell of the spatial grid set up on the slab. As a result of this spectral analysis, we are able to obtain an expression for the local general solution of the SN equations. With this local general solution, we determine the response matrix and use the prescribed boundary conditions and continuity conditions to sweep across the discretization cells from left to right and from right to left across the slab, until a prescribed convergence criterion is satisfied. (author)

Magneto-Spin-Orbit Graphene: Interplay between Exchange and Spin-Orbit Couplings.

Science.gov (United States)

Rybkin, Artem G; Rybkina, Anna A; Otrokov, Mikhail M; Vilkov, Oleg Yu; Klimovskikh, Ilya I; Petukhov, Anatoly E; Filianina, Maria V; Voroshnin, Vladimir Yu; Rusinov, Igor P; Ernst, Arthur; Arnau, Andrés; Chulkov, Evgueni V; Shikin, Alexander M

2018-03-14

A rich class of spintronics-relevant phenomena require implementation of robust magnetism and/or strong spin-orbit coupling (SOC) to graphene, but both properties are completely alien to it. Here, we for the first time experimentally demonstrate that a quasi-freestanding character, strong exchange splitting and giant SOC are perfectly achievable in graphene at once. Using angle- and spin-resolved photoemission spectroscopy, we show that the Dirac state in the Au-intercalated graphene on Co(0001) experiences giant splitting (up to 0.2 eV) while being by no means distorted due to interaction with the substrate. Our calculations, based on the density functional theory, reveal the splitting to stem from the combined action of the Co thin film in-plane exchange field and Au-induced Rashba SOC. Scanning tunneling microscopy data suggest that the peculiar reconstruction of the Au/Co(0001) interface is responsible for the exchange field transfer to graphene. The realization of this "magneto-spin-orbit" version of graphene opens new frontiers for both applied and fundamental studies using its unusual electronic bandstructure.

Coulomb-free and Coulomb-distorted recolliding quantum orbits in photoelectron holography

Science.gov (United States)

Maxwell, A. S.; Figueira de Morisson Faria, C.

2018-06-01

We perform a detailed analysis of the different types of orbits in the Coulomb quantum orbit strong-field approximation (CQSFA), ranging from direct to those undergoing hard collisions. We show that some of them exhibit clear counterparts in the standard formulations of the strong-field approximation for direct and rescattered above-threshold ionization, and show that the standard orbit classification commonly used in Coulomb-corrected models is over-simplified. We identify several types of rescattered orbits, such as those responsible for the low-energy structures reported in the literature, and determine the momentum regions in which they occur. We also find formerly overlooked interference patterns caused by backscattered Coulomb-corrected orbits and assess their effect on photoelectron angular distributions. These orbits improve the agreement of photoelectron angular distributions computed with the CQSFA with the outcome of ab initio methods for high energy phtotoelectrons perpendicular to the field polarization axis.

Optimization of the beam shaping assembly in the D-D neutron generators-based BNCT using the response matrix method.

Science.gov (United States)

Kasesaz, Y; Khalafi, H; Rahmani, F

2013-12-01

Optimization of the Beam Shaping Assembly (BSA) has been performed using the MCNP4C Monte Carlo code to shape the 2.45 MeV neutrons that are produced in the D-D neutron generator. Optimal design of the BSA has been chosen by considering in-air figures of merit (FOM) which consists of 70 cm Fluental as a moderator, 30 cm Pb as a reflector, 2mm (6)Li as a thermal neutron filter and 2mm Pb as a gamma filter. The neutron beam can be evaluated by in-phantom parameters, from which therapeutic gain can be derived. Direct evaluation of both set of FOMs (in-air and in-phantom) is very time consuming. In this paper a Response Matrix (RM) method has been suggested to reduce the computing time. This method is based on considering the neutron spectrum at the beam exit and calculating contribution of various dose components in phantom to calculate the Response Matrix. Results show good agreement between direct calculation and the RM method. Copyright © 2013 Elsevier Ltd. All rights reserved.

Effects of Colored Noise on Periodic Orbits in a One-Dimensional Map

Science.gov (United States)

Li, Feng-Guo; Ai, Bao-Quan

2011-06-01

Noise can induce inverse period-doubling transition and chaos. The effects of the colored noise on periodic orbits, of the different periodic sequences in the logistic map, are investigated. It is found that the dynamical behaviors of the orbits, induced by an exponentially correlated colored noise, are different in the mergence of transition, and the effects of the noise intensity on their dynamical behaviors are different from the effects of the correlation time of noise. Remarkably, the noise can induce new periodic orbits, namely, two new orbits emerge in the period-four sequence at the bifurcation parameter value μ = 3.5, four new orbits in the period-eight sequence at μ = 3.55, and three new orbits in the period-six sequence at μ = 3.846, respectively. Moreover, the dynamical behaviors of the new orbits clearly show the resonancelike response to the colored noise.

Effects of Colored Noise on Periodic Orbits in a One-Dimensional Map

International Nuclear Information System (INIS)

Li Fengguo; Ai Baoquan

2011-01-01

Noise can induce inverse period-doubling transition and chaos. The effects of the colored noise on periodic orbits, of the different periodic sequences in the logistic map, are investigated. It is found that the dynamical behaviors of the orbits, induced by an exponentially correlated colored noise, are different in the mergence of transition, and the effects of the noise intensity on their dynamical behaviors are different from the effects of the correlation time of noise. Remarkably, the noise can induce new periodic orbits, namely, two new orbits emerge in the period-four sequence at the bifurcation parameter value μ = 3.5, four new orbits in the period-eight sequence at μ = 3.55, and three new orbits in the period-six sequence at μ = 3.846, respectively. Moreover, the dynamical behaviors of the new orbits clearly show the resonancelike response to the colored noise. (general)

Orbital Dynamics of Low-Earth Orbit Laser-Propelled Space Vehicles

International Nuclear Information System (INIS)

Yamakawa, Hiroshi; Funaki, Ikkoh; Komurasaki, Kimiya

2008-01-01

Trajectories applicable to laser-propelled space vehicles with a laser station in low-Earth orbit are investigated. Laser vehicles are initially located in the vicinity of the Earth-orbiting laser station in low-earth orbit at an altitude of several hundreds kilometers, and are accelerated by laser beaming from the laser station. The laser-propelled vehicles start from low-earth orbit and finally escape from the Earth gravity well, enabling interplanetary trajectories and planetary exploration

An Orbit And Dispersion Correction Scheme for the PEP II

International Nuclear Information System (INIS)

Cai, Y.; Donald, M.; Shoaee, H.; White, G.; Yasukawa, L.A.

2011-01-01

To achieve optimum luminosity in a storage ring it is vital to control the residual vertical dispersion. In the original PEP storage ring, a scheme to control the residual dispersion function was implemented using the ring orbit as the controlling element. The 'best' orbit not necessarily giving the lowest vertical dispersion. A similar scheme has been implemented in both the on-line control code and in the simulation code LEGO. The method involves finding the response matrices (sensitivity of orbit/dispersion at each Beam-Position-Monitor (BPM) to each orbit corrector) and solving in a least squares sense for minimum orbit, dispersion function or both. The optimum solution is usually a subset of the full least squares solution. A scheme of simultaneously correcting the orbits and dispersion has been implemented in the simulation code and on-line control system for PEP-II. The scheme is based on the eigenvector decomposition method. An important ingredient of the scheme is to choose the optimum eigenvectors that minimize the orbit, dispersion and corrector strength. Simulations indicate this to be a very effective way to control the vertical residual dispersion.

Integrins and extracellular matrix in mechanotransduction

Directory of Open Access Journals (Sweden)

Ramage L

2011-12-01

Full Text Available Lindsay RamageQueen’s Medical Research Institute, University of Edinburgh, Edinburgh, UKAbstract: Integrins are a family of cell surface receptors which mediate cell–matrix and cell–cell adhesions. Among other functions they provide an important mechanical link between the cells external and intracellular environments while the adhesions that they form also have critical roles in cellular signal-transduction. Cell–matrix contacts occur at zones in the cell surface where adhesion receptors cluster and when activated the receptors bind to ligands in the extracellular matrix. The extracellular matrix surrounds the cells of tissues and forms the structural support of tissue which is particularly important in connective tissues. Cells attach to the extracellular matrix through specific cell-surface receptors and molecules including integrins and transmembrane proteoglycans. Integrins work alongside other proteins such as cadherins, immunoglobulin superfamily cell adhesion molecules, selectins, and syndecans to mediate cell–cell and cell–matrix interactions and communication. Activation of adhesion receptors triggers the formation of matrix contacts in which bound matrix components, adhesion receptors, and associated intracellular cytoskeletal and signaling molecules form large functional, localized multiprotein complexes. Cell–matrix contacts are important in a variety of different cell and tissue properties including embryonic development, inflammatory responses, wound healing, and adult tissue homeostasis. This review summarizes the roles and functions of integrins and extracellular matrix proteins in mechanotransduction.Keywords: ligand binding, α subunit, ß subunit, focal adhesion, cell differentiation, mechanical loading, cell–matrix interaction

Effects of Orbital Lifetime Reduction on the Long-Term Earth Satellite Population as Modeled by EVOLVE 4.0

Science.gov (United States)

Krisko, Paula H.; Opiela, John N.; Liou, Jer-Chyi; Anz-Meador, Phillip D.; Theall, Jeffrey R.

1999-01-01

The latest update of the NASA orbital debris environment model, EVOLVE 4.0, has been used to study the effect of various proposed debris mitigation measures, including the NASA 25-year guideline. EVOLVE 4.0, which includes updates of the NASA breakup, solar activity, and the orbit propagator models, a GEO analysis option, and non-fragmentation debris source models, allows for the statistical modeling and predicted growth of the particle population >1 mm in characteristic length in LEO and GEO orbits. The initial implementation of this &odel has been to study the sensitivity of the overall LEO debris environment to mitigation measures designed to limit the lifetime of intact objects in LEO orbits. The mitigation measures test matrix for this study included several commonly accepted testing schemes, i.e., the variance of the maximum LEO lifetime from 10 to 50 years, the date of the initial implementation of this policy, the shut off of all explosions at some specified date, and the inclusion of disposal orbits. All are timely studies in that all scenarios have been suggested by researchers and satellite operators as options for the removal of debris from LEO orbits.

CONGENITAL ORBITAL TERATOMA

African Journals Online (AJOL)

was done without contrast and 3mm/5mm/10mm slices were obtained to cover the orbit, skull base and brain. The findings included a soft tissue mass arising from the orbit. The left eye ball was extra orbital. There was no defect .... love's Short Practice of Surgery. 7 Edition,. Levis London, 1997; 45-64. 2. Orbital tumor Part 1, ...

Theoretical treatment of the spin-orbit coupling in the rare gas oxides NeO, ArO, KrO, and XeO

Science.gov (United States)

Langhoff, S. R.

1980-01-01

Off-diagonal spin-orbit matrix elements are calculated as a function of internuclear distance for the rare gas oxides NeO, ArO, KrO, and XeO using the full microscopic spin-orbit Hamiltonian, including all one- and two-electron integrals, and POL-CI wave functions comparable to those of Dunning and Hay (1977). A good agreement was found when comparing these results in detail with the calculations of Cohen, Wadt and Hay (1979) that utilize an effective one-electron one-center spin-orbit operator. For the rare gas oxide molecules, it is suggested that the numerical results are a more sensitive test of the wave functions (particularly to the extent of charge transfer) than the exact evaluation of all terms in the full spin-orbit operator.

Response matrix of regular moderator volumes with 3He detector using Monte Carlo methods

International Nuclear Information System (INIS)

Baltazar R, A.; Vega C, H. R.; Ortiz R, J. M.; Solis S, L. O.; Castaneda M, R.; Soto B, T. G.; Medina C, D.

2017-10-01

In the last three decades the uses of Monte Carlo methods, for the estimation of physical phenomena associated with the interaction of radiation with matter, have increased considerably. The reason is due to the increase in computing capabilities and the reduction of computer prices. Monte Carlo methods allow modeling and simulating real systems before their construction, saving time and costs. The interaction mechanisms between neutrons and matter are diverse and range from elastic dispersion to nuclear fission; to facilitate the neutrons detection, is necessary to moderate them until reaching electronic equilibrium with the medium at standard conditions of pressure and temperature, in this state the total cross section of the 3 He is large. The objective of the present work was to estimate the response matrix of a proportional detector of 3 He using regular volumes of moderator through Monte Carlo methods. Neutron monoenergetic sources with energies of 10 -9 to 20 MeV and polyethylene moderators of different sizes were used. The calculations were made with the MCNP5 code; the number of stories for each detector-moderator combination was large enough to obtain errors less than 1.5%. We found that for small moderators the highest response is obtained for lower energy neutrons, when increasing the moderator dimension we observe that the response decreases for neutrons of lower energy and increases for higher energy neutrons. The total sum of the responses of each moderator allows obtaining a response close to a constant function. (Author)

Strategy BMT Al-Ittihad Using Matrix IE, Matrix SWOT 8K, Matrix SPACE and Matrix TWOS

Directory of Open Access Journals (Sweden)

Nofrizal Nofrizal

2018-03-01

Full Text Available This research aims to formulate and select BMT Al-Ittihad Rumbai strategy to face the changing of business environment both from internal environment such as organization resources, finance, member and external business such as competitor, economy, politics and others. This research method used Analysis of EFAS, IFAS, IE Matrix, SWOT-8K Matrix, SPACE Matrix and TWOS Matrix. our hope from this research it can assist BMT Al-Ittihad in formulating and selecting strategies for the sustainability of BMT Al-Ittihad in the future. The sample in this research is using purposive sampling technique that is the manager and leader of BMT Al-IttihadRumbaiPekanbaru. The result of this research shows that the position of BMT Al-Ittihad using IE Matrix, SWOT-8K Matrix and SPACE Matrix is in growth position, stabilization and aggressive. The choice of strategy after using TWOS Matrix is market penetration, market development, vertical integration, horizontal integration, and stabilization (careful.

Many-body localization from one particle density matrix

Energy Technology Data Exchange (ETDEWEB)

Bera, Soumya; Bardarson, Jens [Max Planck Institute for the Physics of Complex Systems, Dresden (Germany); Schomerus, Henning [Lancaster University, Lancaster (United Kingdom); Heidrich-Meisner, Fabian [Ludwig-Maximilians-Universitaet Muenchen (Germany)

2016-07-01

We show that the one-particle density matrix ρ can be used to characterize the interaction-driven many-body localization transition in isolated fermionic systems. The natural orbitals (the eigenstates) are localized in the many-body localized phase and spread out when one enters the delocalized phase, while the occupation spectrum (the set of eigenvalues) reveals the distinctive Fock- space structure of the many-body eigenstates, exhibiting a step-like discontinuity in the localized phase. The associated one-particle occupation entropy is small in the localized phase and large in the delocalized phase, with diverging fluctuations at the transition.

Development of the Fragment Molecular Orbital Method for Calculating Nonlocal Excitations in Large Molecular Systems.

Science.gov (United States)

Fujita, Takatoshi; Mochizuki, Yuji

2018-04-19

We developed the fragment-based method for calculating nonlocal excitations in large molecular systems. This method is based on the multilayer fragment molecular orbital method and the configuration interaction single (CIS) wave function using localized molecular orbitals. The excited-state wave function for the whole system is described as a superposition of configuration state functions (CSFs) for intrafragment excitations and for interfragment charge-transfer excitations. The formulation and calculations of singlet excited-state Hamiltonian matrix elements in the fragment CSFs are presented in detail. The efficient approximation schemes for calculating the matrix elements are also presented. The computational efficiency and the accuracy were evaluated using the molecular dimers and molecular aggregates. We confirmed that absolute errors of 50 meV (relative to the conventional calculations) are achievable for the molecular systems in their equilibrium geometries. The perturbative electron correlation correction to the CIS excitation energies is also demonstrated. The present theory can compute a large number of excited states in large molecular systems; in addition, it allows for the systematic derivation of a model exciton Hamiltonian. These features are useful for studying excited-state dynamics in condensed molecular systems based on the ab initio electronic structure theory.

Radiovolumetry of the orbit

International Nuclear Information System (INIS)

Abujamra, S.

1983-01-01

The authors present a method called ''Radiovolumetry of the orbit'' that permits the evaluation of the orbital volume from anteroposterior skull X-Rays (CALDWELL 30 0 position). The research was based in the determination of the orbital volume with lead spheres, in 1010 orbits of 505 dry skulls of Anatomy Museums. After the dry skulls was X-rayed six frontal orbital diameters were made, with care to correct the radiographic amplification. PEARSON correlation coeficient test was applied between the mean orbital diameter and the orbital volume. The result was r = 0,8 with P [pt

Molecular orbital study of iron pentacarbonyl and its photochemical fragments Fe(CO) sub(n)

International Nuclear Information System (INIS)

Guenzburger, D.J.R.; Saitovitch, E.M.B.; De Paoli, M.-A.; Manella, H.

1982-01-01

Self-consistent Molecular Orbital calculations were performed for Fe(CO) 5 and its photofragments Fe(CO) sub(n), 1 5 , photoelectron and optical spectra are analysed, and photochemical behaviour is discussed. The Moessbauer isomer shifts and quadrupole splittings are investigated. In the case of Fe(CO) 5 and Fe(CO) 4 , the values derived for these hyperfine interactions are compared to experimental measurements reported in a polyethylene matrix. (Author) [pt

Density matrix-based time-dependent configuration interaction approach to ultrafast spin-flip dynamics

Science.gov (United States)

Wang, Huihui; Bokarev, Sergey I.; Aziz, Saadullah G.; Kühn, Oliver

2017-08-01

Recent developments in attosecond spectroscopy yield access to the correlated motion of electrons on their intrinsic timescales. Spin-flip dynamics is usually considered in the context of valence electronic states, where spin-orbit coupling is weak and processes related to the electron spin are usually driven by nuclear motion. However, for core-excited states, where the core-hole has a nonzero angular momentum, spin-orbit coupling is strong enough to drive spin-flips on a much shorter timescale. Using density matrix-based time-dependent restricted active space configuration interaction including spin-orbit coupling, we address an unprecedentedly short spin-crossover for the example of L-edge (2p→3d) excited states of a prototypical Fe(II) complex. This process occurs on a timescale, which is faster than that of Auger decay (∼4 fs) treated here explicitly. Modest variations of carrier frequency and pulse duration can lead to substantial changes in the spin-state yield, suggesting its control by soft X-ray light.

Orbital diffuse large B-cell lymphoma with combined variable immunodeficiency.

Science.gov (United States)

Parikh, Vishal S; Jagadeesh, Deepa; Fernandez, James M; Hsi, Eric D; Singh, Arun D

2017-10-01

Common variable immunodeficiency (CVID) is a primary immunodeficiency manifesting as a reduction in the level of total immunoglobulin (Ig) G, a reduction in the level of either IgA or IgM, poor response to polysaccharide vaccine, and usually frequent infections. The association of CVID with an increased risk of malignancy, specifically lymphoma, is well known. A 63-year-old female with a past medical history significant for CVID presented with a 1-month history of dull, left eye pain with proptosis, hypoglobus, and left upper lid fullness without a discrete palpable mass. Magnetic resonance imaging (MRI) of the orbits revealed a diffuse infiltrating orbital mass superonasally with extension into the superior rectus muscle, medial rectus muscle, and optic nerve up to the orbital apex and ethmoid sinus. A superonasal orbital biopsy with a caruncular approach was performed and demonstrated a sparse lymphoid infiltrate that was suggestive for a large B-cell neoplasm. Positron emission tomography (PET) scan demonstrated a hypermetabolic right lymph node, anterior to the right submandibular gland, which was biopsied and histopathology confirmed diffuse large B-cell lymphoma (DLBCL). Our patient achieved a very good response to chemotherapy with minimal residual disease on PET scan at the end of treatment. She attained a complete remission after radiation therapy. In conclusion, patients with new orbital and adnexa masses in the setting of a primary immunodeficiency can have an aggressive malignancy such as DLBCL and early diagnosis and systemic treatment carries a good prognosis.

Half-metal phases in a quantum wire with modulated spin-orbit interaction

Science.gov (United States)

Cabra, D. C.; Rossini, G. L.; Ferraz, A.; Japaridze, G. I.; Johannesson, H.

2017-11-01

We propose a spin filter device based on the interplay of a modulated spin-orbit interaction and a uniform external magnetic field acting on a quantum wire. Half-metal phases, where electrons with only a selected spin polarization exhibit ballistic conductance, can be tuned by varying the magnetic field. These half-metal phases are proven to be robust against electron-electron repulsive interactions. Our results arise from a combination of explicit band diagonalization, bosonization techniques, and extensive density matrix renormalization group computations.

Authorship matrix: a rational approach to quantify individual contributions and responsibilities in multi-author scientific articles.

Science.gov (United States)

Clement, T Prabhakar

2014-06-01

We propose a rational method for addressing an important question-who deserves to be an author of a scientific article? We review various contentious issues associated with this question and recommend that the scientific community should view authorship in terms of contributions and responsibilities, rather than credits. We propose a new paradigm that conceptually divides a scientific article into four basic elements: ideas, work, writing, and stewardship. We employ these four fundamental elements to modify the well-known International Committee of Medical Journal Editors (ICMJE) authorship guidelines. The modified ICMJE guidelines are then used as the basis to develop an approach to quantify individual contributions and responsibilities in multi-author articles. The outcome of the approach is an authorship matrix, which can be used to answer several nagging questions related to authorship.

Characteristics of persistent spin current components in a quasi-periodic Fibonacci ring with spin–orbit interactions: Prediction of spin–orbit coupling and on-site energy

International Nuclear Information System (INIS)

Patra, Moumita; Maiti, Santanu K.

2016-01-01

In the present work we investigate the behavior of all three components of persistent spin current in a quasi-periodic Fibonacci ring subjected to Rashba and Dresselhaus spin–orbit interactions. Analogous to persistent charge current in a conducting ring where electrons gain a Berry phase in presence of magnetic flux, spin Berry phase is associated during the motion of electrons in presence of a spin–orbit field which is responsible for the generation of spin current. The interplay between two spin–orbit fields along with quasi-periodic Fibonacci sequence on persistent spin current is described elaborately, and from our analysis, we can estimate the strength of any one of two spin–orbit couplings together with on-site energy, provided the other is known. - Highlights: • Determination of Rashba and Dresselhaus spin–orbit fields is discussed. • Characteristics of all three components of spin current are explored. • Possibility of estimating on-site energy is given. • Results can be generalized to any lattice models.

Characteristics of persistent spin current components in a quasi-periodic Fibonacci ring with spin–orbit interactions: Prediction of spin–orbit coupling and on-site energy

Energy Technology Data Exchange (ETDEWEB)

Patra, Moumita; Maiti, Santanu K., E-mail: santanu.maiti@isical.ac.in

2016-12-15

In the present work we investigate the behavior of all three components of persistent spin current in a quasi-periodic Fibonacci ring subjected to Rashba and Dresselhaus spin–orbit interactions. Analogous to persistent charge current in a conducting ring where electrons gain a Berry phase in presence of magnetic flux, spin Berry phase is associated during the motion of electrons in presence of a spin–orbit field which is responsible for the generation of spin current. The interplay between two spin–orbit fields along with quasi-periodic Fibonacci sequence on persistent spin current is described elaborately, and from our analysis, we can estimate the strength of any one of two spin–orbit couplings together with on-site energy, provided the other is known. - Highlights: • Determination of Rashba and Dresselhaus spin–orbit fields is discussed. • Characteristics of all three components of spin current are explored. • Possibility of estimating on-site energy is given. • Results can be generalized to any lattice models.

Exploring one-particle orbitals in large many-body localized systems

Science.gov (United States)

Villalonga, Benjamin; Yu, Xiongjie; Luitz, David J.; Clark, Bryan K.

2018-03-01

Strong disorder in interacting quantum systems can give rise to the phenomenon of many-body localization (MBL), which defies thermalization due to the formation of an extensive number of quasilocal integrals of motion. The one-particle operator content of these integrals of motion is related to the one-particle orbitals (OPOs) of the one-particle density matrix and shows a strong signature across the MBL transition as recently pointed out by Bera et al. [Phys. Rev. Lett. 115, 046603 (2015), 10.1103/PhysRevLett.115.046603; Ann. Phys. 529, 1600356 (2017), 10.1002/andp.201600356]. We study the properties of the OPOs of many-body eigenstates of an MBL system in one dimension. Using shift-and-invert MPS, a matrix product state method to target highly excited many-body eigenstates introduced previously [Phys. Rev. Lett. 118, 017201 (2017), 10.1103/PhysRevLett.118.017201], we are able to obtain accurate results for large systems of sizes up to L =64 . We find that the OPOs drawn from eigenstates at different energy densities have high overlap and their occupations are correlated with the energy of the eigenstates. Moreover, the standard deviation of the inverse participation ratio of these orbitals is maximal at the nose of the mobility edge. Also, the OPOs decay exponentially in real space, with a correlation length that increases at low disorder. In addition, we find that the probability distribution of the strength of the large-range coupling constants of the number operators generated by the OPOs approach a log-uniform distribution at strong disorder.

CELLULAR CONTROL OF CONNECTIVE TISSUE MATRIX TENSION†

Science.gov (United States)

Langevin, Helene M.; Nedergaard, Maiken; Howe, Alan

2013-01-01

The biomechanical behavior of connective tissue in response to stretching is generally attributed to the molecular composition and organization of its extracellular matrix. It also is becoming apparent that fibroblasts play an active role in regulating connective tissue tension. In response to static stretching of the tissue, fibroblasts expand within minutes by actively remodeling their cytoskeleton. This dynamic change in fibroblast shape contributes to the drop in tissue tension that occurs during viscoelastic relaxation. We propose that this response of fibroblasts plays a role in regulating extracellular fluid flow into the tissue, and protects against swelling when the matrix is stretched. This article reviews the evidence supporting possible mechanisms underlying this response including autocrine purinergic signaling. We also discuss fibroblast regulation of connective tissue tension with respect to lymphatic flow, immune function and cancer. PMID:23444198

Cellular control of connective tissue matrix tension.

Science.gov (United States)

Langevin, Helene M; Nedergaard, Maiken; Howe, Alan K

2013-08-01

The biomechanical behavior of connective tissue in response to stretching is generally attributed to the molecular composition and organization of its extracellular matrix. It also is becoming apparent that fibroblasts play an active role in regulating connective tissue tension. In response to static stretching of the tissue, fibroblasts expand within minutes by actively remodeling their cytoskeleton. This dynamic change in fibroblast shape contributes to the drop in tissue tension that occurs during viscoelastic relaxation. We propose that this response of fibroblasts plays a role in regulating extracellular fluid flow into the tissue, and protects against swelling when the matrix is stretched. This article reviews the evidence supporting possible mechanisms underlying this response including autocrine purinergic signaling. We also discuss fibroblast regulation of connective tissue tension with respect to lymphatic flow, immune function, and cancer. Copyright © 2013 Wiley Periodicals, Inc.

Spatially dependent burnup implementation into the nodal program based on the finite element response matrix method

International Nuclear Information System (INIS)

Yoriyaz, H.

1986-01-01

In this work a spatial burnup scheme and feedback effects has been implemented into the FERM ( 'Finite Element Response Matrix' )program. The spatially dependent neutronic parameters have been considered in three levels: zonewise calculation, assembly wise calculation and pointwise calculation. Flux and power distributions and the multiplication factor were calculated and compared with the results obtained by CITATIOn program. These comparisons showed that processing time in the Ferm code has been hundred of times shorter and no significant difference has been observed in the assembly average power distribution. (Author) [pt

Orbital wall fractures

International Nuclear Information System (INIS)

Iinuma, Toshitaka; Ishio, Ken-ichirou; Yoshinami, Hiroyoshi; Kuriyama, Jun-ichi; Hirota, Yoshiharu.

1993-01-01

A total of 59 cases of mild facial fractures (simple orbital wall fractures, 34 cases, other facial fractures, 25 cases) with the clinical suspects of orbital wall fractures were evaluated both by conventional views (Waters' and Caldwell views) and coronal CT scans. Conventional views were obtained, as an average, after 4 days and CT after 7 days of injuries. Both the medial wall and the floor were evaluated at two sites, i.e., anterior and posterior. The ethmoid-maxillary plate was also included in the study. The degree of fractures was classified as, no fractures, fractures of discontinuity, dislocation and fragmentation. The coronal CT images in bone window condition was used as reference and the findings were compared between conventional views and CT. The correct diagnosis was obtained as follows: orbital floor (anterior, 78%, posterior, 73%), medial orbital wall (anterior, 72%, posterior, 72%) and ethmoid-maxillary plate (64%). The false positive diagnosis was as follows: orbital floor (anterior only, 13%), medial orbital wall (anterior only, 7%) and ethmoid-maxillary plate (11%). The false negative diagnosis was as follows: orbital floor (anterior, 9%, posterior, 10%), medial orbital wall (anterior, 21%, posterior, 28%) and ethmoid-maxillary plate (21%). The results were compared with those of others in the past. (author)

A matrix model from string field theory

Directory of Open Access Journals (Sweden)

Syoji Zeze

2016-09-01

Full Text Available We demonstrate that a Hermitian matrix model can be derived from level truncated open string field theory with Chan-Paton factors. The Hermitian matrix is coupled with a scalar and U(N vectors which are responsible for the D-brane at the tachyon vacuum. Effective potential for the scalar is evaluated both for finite and large N. Increase of potential height is observed in both cases. The large $N$ matrix integral is identified with a system of N ZZ branes and a ghost FZZT brane.

Orbitals, correlation, valencies in high-Tc superconductors

International Nuclear Information System (INIS)

Khomskii, D.I.

1990-09-01

The survey is given of certain properties of high-Tc superconductors connected with the details of their electronic structure such as the kind of orbitals involved and the degree of correlation. Special attention is paid to the properties of cuprates at high doping level. The problem whether there exists a ''Mott transition'' at high electron or a hole concentration is discussed. We also discuss physical factors (d-p Coulomb interaction, orbital mixing) leading to the partial occupation of copper d x 2 -orbital. In particular we show that in localized picture (x 2 -y 2 ) and z 2 -levels in La 2-x Sr x CuO 4 may cross at x approx. 0.4 which may be responsible for a marked change of many properties at this doping. The possible role of x 2 -electrons in pairing is discussed in connection with some recent experiments. (author). 28 refs, 6 figs, 1 tab

Economic analysis requirements in support of orbital debris regulatory policy

Science.gov (United States)

Greenberg, Joel S.

1996-10-01

As the number of Earth orbiting objects increases so does the potential for generating orbital debris with the consequent increase in the likelihood of impacting and damaging operating satellites. Various debris remediation approaches are being considered that encompass both in-orbit and return-to-Earth schema and have varying degrees of operations, cost, international competitiveness, and safety implications. Because of the diversity of issues, concerns and long-term impacts, there is a clear need for the setting of government policies that will lead to an orderly abatement of the potential orbital debris hazards. These policies may require the establishment of a supportive regulatory regime. The Department of Transportation is likely to have regulatory responsibilities relating to orbital debris stemming from its charge to protect the public health and safety, safety of property, and national security interests and foreign policy interests of the United States. This paper describes DOT's potential regulatory role relating to orbital debris remediation, the myriad of issues concerning the need for establishing government policies relating to orbital debris remediation and their regulatory implications, the proposed technological solutions and their economic and safety implications. Particular emphasis is placed upon addressing cost-effectiveness and economic analyses as they relate to economic impact analysis in support of regulatory impact analysis.

Spin-orbit coupling and the static polarizability of single-wall carbon nanotubes

International Nuclear Information System (INIS)

Diniz, Ginetom S.; Ulloa, Sergio E.

2014-01-01

We calculate the static longitudinal polarizability of single-wall carbon tubes in the long wavelength limit taking into account spin-orbit effects. We use a four-orbital orthogonal tight-binding formalism to describe the electronic states and the random phase approximation to calculate the dielectric function. We study the role of both the Rashba as well as the intrinsic spin-orbit interactions on the longitudinal dielectric response, i.e., when the probing electric field is parallel to the nanotube axis. The spin-orbit interaction modifies the nanotube electronic band dispersions, which may especially result in a small gap opening in otherwise metallic tubes. The bandgap size and state features, the result of competition between Rashba and intrinsic spin-orbit interactions, result in drastic changes in the longitudinal static polarizability of the system. We discuss results for different nanotube types and the dependence on nanotube radius and spin-orbit couplings.

Spin-orbit coupling and the static polarizability of single-wall carbon nanotubes

Energy Technology Data Exchange (ETDEWEB)

Diniz, Ginetom S., E-mail: ginetom@gmail.com; Ulloa, Sergio E. [Department of Physics and Astronomy and Nanoscale and Quantum Phenomena Institute, Ohio University, Athens, Ohio 45701-2979 (United States)

2014-07-14

We calculate the static longitudinal polarizability of single-wall carbon tubes in the long wavelength limit taking into account spin-orbit effects. We use a four-orbital orthogonal tight-binding formalism to describe the electronic states and the random phase approximation to calculate the dielectric function. We study the role of both the Rashba as well as the intrinsic spin-orbit interactions on the longitudinal dielectric response, i.e., when the probing electric field is parallel to the nanotube axis. The spin-orbit interaction modifies the nanotube electronic band dispersions, which may especially result in a small gap opening in otherwise metallic tubes. The bandgap size and state features, the result of competition between Rashba and intrinsic spin-orbit interactions, result in drastic changes in the longitudinal static polarizability of the system. We discuss results for different nanotube types and the dependence on nanotube radius and spin-orbit couplings.

Pairing tendencies in a two-orbital Hubbard model in one dimension

Energy Technology Data Exchange (ETDEWEB)

Patel, Niravkumar D. [The Univ. of Tennessee, Knoxville, TN (United States); Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Nocera, Adriana [The Univ. of Tennessee, Knoxville, TN (United States); Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Alvarez, Gonzalo [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Moreo, A. [The Univ. of Tennessee, Knoxville, TN (United States); Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Dagotto, Elbio R. [The Univ. of Tennessee, Knoxville, TN (United States); Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

2017-07-31

The recent discovery of superconductivity under high pressure in the ladder compound BaFe2S3 has opened a new field of research in iron-based superconductors with focus on quasi-one-dimensional geometries. In this publication, using the density matrix renormalization group technique, we study a two-orbital Hubbard model defined in one-dimensional chains. Our main result is the presence of hole binding tendencies at intermediate Hubbard U repulsion and robust Hund coupling J_H / U = 0.25. Binding does not occur either in weak coupling or at very strong coupling. The pair-pair correlations that are dominant near half-filling, or of similar strength as the charge and spin correlation channels, involve hole-pair operators that are spin singlets, use nearest-neighbor sites, and employ different orbitals for each hole. As a result, the Hund coupling strength, presence of robust magnetic moments, and antiferromagnetic correlations among them are important for the binding tendencies found here.

Development of 10×10 Matrix-anode MCP-PMT

Science.gov (United States)

Yang, Jie; Li, Yongbin; Xu, Pengxiao; Zhao, Wenjin

2018-02-01

10×10 matrix-anode is developed by high-temperature co-fired ceramics (HTCC) technology. Based on the new matrix-anode, a new kind of photon counting imaging detector - 10×10 matrix-anode MCP-PMT is developed, and its performance parameters are tested. HTCC technology is suitable for the MCP-PMT's air impermeability and its baking process. Its response uniformity is better than the metal-ceramic or metal-glass sealing anode, and it is also a promising method to realize a higher density matrix-anode.

The relativistic electron response at geosynchronous orbit during the January 1997 magnetic storm

International Nuclear Information System (INIS)

Reeves, G.D.; Friedel, R.H.; Belian, R.D.; Meier, M.M.; Henderson, M.G.; Onsager, T.; Singer, H.J.; Baker, D.N.; Li, X.

1998-01-01

The first geomagnetic storm of 1997 began on January 10. It is of particular interest because it was exceptionally well observed by the full complement of International Solar Terrestrial Physics (ISTP) satellites and because of its possible association with the catastrophic failure of the Telstar 401 telecommunications satellite. Here we report on the energetic electron environment observed by five geosynchronous satellites. In part one of this paper we examine the magnetospheric response to the magnetic cloud. The interval of southward IMF drove strong substorm activity while the interval of northward IMF and high solar wind density strongly compressed the magnetosphere. At energies above a few hundred keV, two distinct electron enhancements were observed at geosynchronous orbit. The first enhancement began and ended suddenly, lasted for approximately 1 day, and is associated with the strong compression of the magnetosphere. The second enhancement showed a more characteristic time delay, peaking on January 15. Both enhancements may be due to transport of electrons from the same initial acceleration event at a location inside geosynchronous orbit but the first enhancement was due to a temporary, quasi-adiabatic transport associated with the compression of the magnetosphere while the second enhancement was due to slower diffusive processes. In the second part of the paper we compare the relativistic electron fluxes measured simultaneously at different local times. We find that the >2-MeV electron fluxes increased first at noon followed by dusk and then dawn and that there can be difference of two orders of magnitude in the fluxes observed at different local times. Finally, we discuss the development of data-driven models of the relativistic electron belts for space weather applications. By interpolating fluxes between satellites we produced a model that gives the >2-MeV electron fluxes at all local times as a function of universal time. In a first application of

A new program for calculating matrix elements of one-particle operators in jj-coupling

International Nuclear Information System (INIS)

Pyper, N.C.; Grant, I.P.; Beatham, N.

1978-01-01

The aim of this paper is to calculate the matrix elements of one-particle tensor operators occurring in atomic and nuclear theory between configuration state functions representing states containing any number of open shells in jj-coupling. The program calculates the angular part of these matrix elements. The program is essentially a new version of RDMEJJ, written by J.J. Chang. The aims of this version are to eliminate inconsistencies from RDMEJJ, to modify its input requirements for consistency with MCP75, and to modify its output so that it can be stored in a discfile for access by other compatible programs. The program assumes that the configurational states are built from a common orthonormal set of basis orbitals. The number of electrons in a shell having j>=9/2 is restricted to be not greater than 2 by the available CFP routines . The present version allows up to 40 orbitals and 50 configurational states with <=10 open shells; these numbers can be changed by recompiling with modified COMMON/DIMENSION statements. The user should ensure that the CPC library subprograms AAGD, ACRI incorporate all current updates and have been converted to use double precision floating point arithmetic. (Auth.)

Identification of generalized state transfer matrix using neural networks

International Nuclear Information System (INIS)

Zhu Changchun

2001-01-01

The research is introduced on identification of generalized state transfer matrix of linear time-invariant (LTI) system by use of neural networks based on LM (Levenberg-Marquart) algorithm. Firstly, the generalized state transfer matrix is defined. The relationship between the identification of state transfer matrix of structural dynamics and the identification of the weight matrix of neural networks has been established in theory. A singular layer neural network is adopted to obtain the structural parameters as a powerful tool that has parallel distributed processing ability and the property of adaptation or learning. The constraint condition of weight matrix of the neural network is deduced so that the learning and training of the designed network can be more effective. The identified neural network can be used to simulate the structural response excited by any other signals. In order to cope with its further application in practical problems, some noise (5% and 10%) is expected to be present in the response measurements. Results from computer simulation studies show that this method is valid and feasible

Role of the Co-based microwires/polymer matrix interface on giant magneto impedance response

International Nuclear Information System (INIS)

Estévez, Diana; Li, Jiawei; Liu, Gang; Man, Qikui; Chang, Chuntao; Wang, Xinmin; Li, Run-Wei

2015-01-01

Highlights: • Co-based microwires-epoxy interface was modified with silane and GMI was evaluated. • XPS confirmed the adhesion of silane onto the wires by Si–O–Si and Fe–O–Si bonds. • GMI curves for treated samples exhibited two-peak behavior and higher GMI ratio. • GMI variation was explained by the change of the surface magnetic anisotropy. • GMI could potentially be used as a surface scanning technique. - Abstract: The interface of Co-based microwires-epoxy composites was modified by applying silane treatment on the surface of the wires and their magneto impedance (MI) response was evaluated. The aim of the surface treatment was to modify the residual stresses that coexist at the microwires/polymer matrix interface and hence the magnetic anisotropy. X-ray Photoelectron Spectroscopy confirmed the covalent attachment of silane molecule onto the wires surface by the presence of Si–O–Si and Fe–O–Si. The MI curve changed from single peak for untreated samples to double peak behavior for treated samples with a significant improvement of MI ratio. Additionally, the magnitude of the anisotropy field increased with the frequency, which may imply a strongly non-uniform stress distribution towards the surface. The MI variation was explained by the change of the surface magnetic anisotropy owing to the modification of the microwires/polymer matrix interface

Traumatic orbital CSF leak

Science.gov (United States)

Borumandi, Farzad

2013-01-01

Compared to the cerebrospinalfluid (CSF) leak through the nose and ear, the orbital CSF leak is a rare and underreported condition following head trauma. We present the case of a 49-year-old woman with oedematous eyelid swelling and ecchymosis after a seemingly trivial fall onto the right orbit. Apart from the above, she was clinically unremarkable. The CT scan revealed a minimally displaced fracture of the orbital roof with no emphysema or intracranial bleeding. The fractured orbital roof in combination with the oedematous eyelid swelling raised the suspicion for orbital CSF leak. The MRI of the neurocranium demonstrated a small-sized CSF fistula extending from the anterior cranial fossa to the right orbit. The patient was treated conservatively and the lid swelling resolved completely after 5 days. Although rare, orbital CSF leak needs to be included in the differential diagnosis of periorbital swelling following orbital trauma. PMID:24323381

Immobilization of mercury and zinc in an alkali-activated slag matrix.

Science.gov (United States)

Qian, Guangren; Sun, Darren Delai; Tay, Joo Hwa

2003-07-04

The behavior of heavy metals mercury and zinc immobilized in an alkali-activated slag (AAS) matrix has been evaluated using physical property tests, pore structure analysis and XRD, TG-DTG, FTIR and TCLP analysis. Low concentrations (0.5%) of mercury and zinc ions had only a slight affect on compressive strength, pore structure and hydration of AAS matrixes. The addition of 2% Hg ions to the AAS matrix resulted in a reduction in early compressive strength but no negative effects were noticed after 28 days of hydration. Meanwhile, 2% Hg ions can be effectively immobilized in the AAS matrix with the leachate meeting the USEPA TCLP mercury limit. For a 2% Zn-doped AAS matrix, the hydration of the AAS paste was greatly retarded and the zinc concentration in the leachate from this matrix was higher than 5mg/l even at 28 days. Based on these results, we conclude that the physical encapsulation and chemical fixation mechanisms were likely to be responsible for the immobilization of Hg ions in the AAS matrix while only chemical fixation mechanisms were responsible for the immobilization of Zn ions in the AAS matrix.

A study on measurement on artificial radiation dose rate using the response matrix method

International Nuclear Information System (INIS)

Kidachi, Hiroshi; Ishikawa, Yoichi; Konno, Tatsuya

2004-01-01

We examined accuracy and stability of estimated artificial dose contribution which is distinguished from natural background gamma-ray dose rate using Response Matrix method. Irradiation experiments using artificial gamma-ray sources indicated that there was a linear relationship between observed dose rate and estimated artificial dose contribution, when irradiated artificial gamma-ray dose rate was higher than about 2 nGy/h. Statistical and time-series analyses of long term data made it clear that estimated artificial contribution showed almost constant values under no artificial influence from the nuclear power plants. However, variations of estimated artificial dose contribution were infrequently observed due to of rainfall, detector maintenance operation and occurrence of calibration error. Some considerations on the factors to these variations were made. (author)

Estimating the two-particle K-matrix for multiple partial waves and decay channels from finite-volume energies

Directory of Open Access Journals (Sweden)

Colin Morningstar

2017-11-01

Full Text Available An implementation of estimating the two-to-two K-matrix from finite-volume energies based on the Lüscher formalism and involving a Hermitian matrix known as the “box matrix” is described. The method includes higher partial waves and multiple decay channels. Two fitting procedures for estimating the K-matrix parameters, which properly incorporate all statistical covariances, are discussed. Formulas and software for handling total spins up to S=2 and orbital angular momenta up to L=6 are obtained for total momenta in several directions. First tests involving ρ-meson decay to two pions include the L=3 and L=5 partial waves, and the contributions from these higher waves are found to be negligible in the elastic energy range.

Efficacy of Vismodegib (Erivedge) for Basal Cell Carcinoma Involving the Orbit and Periocular Area.

Science.gov (United States)

Demirci, Hakan; Worden, Francis; Nelson, Christine C; Elner, Victor M; Kahana, Alon

2015-01-01

Evaluate the effectiveness of vismodegib in the management of basal cell carcinoma with orbital extension and/or extensive periocular involvement. Retrospective chart review of 6 consecutive patients with biopsy-proven orbital basal cell carcinoma and 2 additional patients with extensive periocular basal cell carcinoma who were treated with oral vismodegib (150 mg/day) was performed. Basal cell carcinoma extended in the orbit in 6 of 8 patients (involving orbital bones in 1 patient), and 2 of 8 patients had extensive periocular involvement (1 with basal cell nevus syndrome). Vismodegib therapy was the only treatment in 6 patients, off-label neoadjuvant in 1 patient, and adjuvant treatment in 1 patient. Orbital tumors in all 4 patients who received vismodegib as sole treatment showed partial response with a mean 83% shrinkage in tumor size after a median of 7 months of therapy. In the 2 patients receiving vismodegib as neoadjuvant or adjuvant therapies, there was complete response after a median of 7 months of therapy and no evidence of clinical recurrence after discontinuing therapy for a median of 15 months. The 2 patients with extensive periocular involvement experienced complete clinical response after a median 14 months of treatment. During treatment, the most common side effects were muscle spasm (75%) followed by alopecia (50%), dysgeusia (25%), dysosmia, and episodes of diarrhea and constipation (13%). Basal cell carcinoma with orbital extension and extensive periocular involvement responds to vismodegib therapy. The long-term prognosis remains unknown, and additional prospective studies are indicated.

Response of air-sea carbon fluxes and climate to orbital forcing changes in the Community Climate System Model

Science.gov (United States)

Jochum, M.; Peacock, S.; Moore, K.; Lindsay, K.

2010-07-01

A global general circulation model coupled to an ocean ecosystem model is used to quantify the response of carbon fluxes and climate to changes in orbital forcing. Compared to the present-day simulation, the simulation with the Earth's orbital parameters from 115,000 years ago features significantly cooler northern high latitudes but only moderately cooler southern high latitudes. This asymmetry is explained by a 30% reduction of the strength of the Atlantic Meridional Overturning Circulation that is caused by an increased Arctic sea ice export and a resulting freshening of the North Atlantic. The strong northern high-latitude cooling and the direct insolation induced tropical warming lead to global shifts in precipitation and winds to the order of 10%-20%. These climate shifts lead to regional differences in air-sea carbon fluxes of the same order. However, the differences in global net air-sea carbon fluxes are small, which is due to several effects, two of which stand out: first, colder sea surface temperature leads to a more effective solubility pump but also to increased sea ice concentration which blocks air-sea exchange, and second, the weakening of Southern Ocean winds that is predicted by some idealized studies occurs only in part of the basin, and is compensated by stronger winds in other parts.

A multiple-orbit time-of-flight mass spectrometer based on a low energy electrostatic storage ring

Science.gov (United States)

Sullivan, M. R.; Spanjers, T. L.; Thorn, P. A.; Reddish, T. J.; Hammond, P.

2012-11-01

The results are presented for an electrostatic storage ring, consisting of two hemispherical deflector analyzers (HDA) connected by two separate sets of cylindrical lenses, used as a time-of-flight mass spectrometer. Based on the results of charged particle simulations and formal matrix model, the Ion Storage Ring is capable of operating with multiple stable orbits, for both single and multiply charged ions simultaneously.

Spin-orbit torques in magnetic bilayers

Science.gov (United States)

Haney, Paul

2015-03-01

Spintronics aims to utilize the coupling between charge transport and magnetic dynamics to develop improved and novel memory and logic devices. Future progress in spintronics may be enabled by exploiting the spin-orbit coupling present at the interface between thin film ferromagnets and heavy metals. In these systems, applying an in-plane electrical current can induce magnetic dynamics in single domain ferromagnets, or can induce rapid motion of domain wall magnetic textures. There are multiple effects responsible for these dynamics. They include spin-orbit torques and a chiral exchange interaction (the Dzyaloshinskii-Moriya interaction) in the ferromagnet. Both effects arise from the combination of ferromagnetism and spin-orbit coupling present at the interface. There is additionally a torque from the spin current flux impinging on the ferromagnet, arising from the spin hall effect in the heavy metal. Using a combination of approaches, from drift-diffusion to Boltzmann transport to first principles methods, we explore the relative contributions to the dynamics from these different effects. We additionally propose that the transverse spin current is locally enhanced over its bulk value in the vicinity of an interface which is oriented normal to the charge current direction.

Electrically tunable spin polarization in silicene: A multi-terminal spin density matrix approach

International Nuclear Information System (INIS)

Chen, Son-Hsien

2016-01-01

Recent realized silicene field-effect transistor yields promising electronic applications. Using a multi-terminal spin density matrix approach, this paper presents an analysis of the spin polarizations in a silicene structure of the spin field-effect transistor by considering the intertwined intrinsic and Rashba spin–orbit couplings, gate voltage, Zeeman splitting, as well as disorder. Coexistence of the stagger potential and intrinsic spin–orbit coupling results in spin precession, making any in-plane polarization directions reachable by the gate voltage; specifically, the intrinsic coupling allows one to electrically adjust the in-plane components of the polarizations, while the Rashba coupling to adjust the out-of-plan polarizations. Larger electrically tunable ranges of in-plan polarizations are found in oppositely gated silicene than in the uniformly gated silicene. Polarizations in different phases behave distinguishably in weak disorder regime, while independent of the phases, stronger disorder leads to a saturation value. - Highlights: • Density matrix with spin rotations enables multi-terminal arbitrary spin injections. • Gate-voltage tunable in-plane polarizations require intrinsic SO coupling. • Gate-voltage tunable out-of-plane polarizations require Rashba SO coupling. • Oppositely gated silicene yields a large tunable range of in-plan polarizations. • Polarizations in different phases behave distinguishably only in weak disorder.

Higher order spin-dependent terms in D0-brane scattering from the matrix model

International Nuclear Information System (INIS)

McArthur, I.N.

1998-01-01

The potential describing long-range interactions between D0-branes contains spin-dependent terms. In the matrix model, these should be reproduced by the one-loop effective action computed in the presence of a non-trivial fermionic background ψ. The v 3 ψ 2 /r 8 term in the effective action has been computed by Kraus and shown to correspond to a spin-orbit interaction between D0-branes, and the ψ 8 /r 11 term in the static potential has been obtained by Barrio et al. In this paper, the v 2 ψ 4 /r 9 term is computing in the matrix model and compared with the corresponding results of Morales et al. obtained using string theoretic methods. The technique employed is adapted to the underlying supersymmetry of the matrix model, and should be useful in the calculation of spin-dependent effects in more general Dp-brane scatterings. (orig.)

Monsoonal response to mid-holocene orbital forcing in a high resolution GCM

Directory of Open Access Journals (Sweden)

J. H. C. Bosmans

2012-04-01

Full Text Available In this study, we use a sophisticated high-resolution atmosphere-ocean coupled climate model, EC-Earth, to investigate the effect of Mid-Holocene orbital forcing on summer monsoons on both hemispheres. During the Mid-Holocene (6 ka, there was more summer insolation on the Northern Hemisphere than today, which intensified the meridional temperature and pressure gradients. Over North Africa, monsoonal precipitation is intensified through increased landward monsoon winds and moisture advection as well as decreased moisture convergence over the oceans and more convergence over land compared to the pre-industrial simulation. Precipitation also extends further north as the ITCZ shifts northward in response to the stronger poleward gradient of insolation. This increase and poleward extent is stronger than in most previous ocean-atmosphere GCM simulations. In north-westernmost Africa, precipitation extends up to 35° N. Over tropical Africa, internal feedbacks completely overcome the direct warming effect of increased insolation. We also find a weakened African Easterly Jet. Over Asia, monsoonal precipitation during the Mid-Holocene is increased as well, but the response is different than over North-Africa. There is more convection over land at the expense of convection over the ocean, but precipitation does not extend further northward, monsoon winds over the ocean are weaker and the surrounding ocean does not provide more moisture. On the Southern Hemisphere, summer insolation and the poleward insolation gradient were weaker during the Mid-Holocene, resulting in a reduced South American monsoon through decreased monsoon winds and less convection, as well as an equatorward shift in the ITCZ. This study corroborates the findings of paleodata research as well as previous model studies, while giving a more detailed account of Mid-Holocene monsoons.

Antisymmetric Orbit Functions

Directory of Open Access Journals (Sweden)

Anatoliy Klimyk

2007-02-01

Full Text Available In the paper, properties of antisymmetric orbit functions are reviewed and further developed. Antisymmetric orbit functions on the Euclidean space $E_n$ are antisymmetrized exponential functions. Antisymmetrization is fulfilled by a Weyl group, corresponding to a Coxeter-Dynkin diagram. Properties of such functions are described. These functions are closely related to irreducible characters of a compact semisimple Lie group $G$ of rank $n$. Up to a sign, values of antisymmetric orbit functions are repeated on copies of the fundamental domain $F$ of the affine Weyl group (determined by the initial Weyl group in the entire Euclidean space $E_n$. Antisymmetric orbit functions are solutions of the corresponding Laplace equation in $E_n$, vanishing on the boundary of the fundamental domain $F$. Antisymmetric orbit functions determine a so-called antisymmetrized Fourier transform which is closely related to expansions of central functions in characters of irreducible representations of the group $G$. They also determine a transform on a finite set of points of $F$ (the discrete antisymmetric orbit function transform. Symmetric and antisymmetric multivariate exponential, sine and cosine discrete transforms are given.

Angles-only relative orbit determination in low earth orbit

Science.gov (United States)

Ardaens, Jean-Sébastien; Gaias, Gabriella

2018-06-01

The paper provides an overview of the angles-only relative orbit determination activities conducted to support the Autonomous Vision Approach Navigation and Target Identification (AVANTI) experiment. This in-orbit endeavor was carried out by the German Space Operations Center (DLR/GSOC) in autumn 2016 to demonstrate the capability to perform spaceborne autonomous close-proximity operations using solely line-of-sight measurements. The images collected onboard have been reprocessed by an independent on-ground facility for precise relative orbit determination, which served as ultimate instance to monitor the formation safety and to characterize the onboard navigation and control performances. During two months, several rendezvous have been executed, generating a valuable collection of images taken at distances ranging from 50 km to only 50 m. Despite challenging experimental conditions characterized by a poor visibility and strong orbit perturbations, angles-only relative positioning products could be continuously derived throughout the whole experiment timeline, promising accuracy at the meter level during the close approaches. The results presented in the paper are complemented with former angles-only experience gained with the PRISMA satellites to better highlight the specificities induced by different orbits and satellite designs.

Chaos and nonlinear dynamics of single-particle orbits in a magnetotaillike magnetic field

Science.gov (United States)

Chen, J.; Palmadesso, P. J.

1986-01-01

The properties of charged-particle motion in Hamiltonian dynamics are studied in a magnetotaillike magnetic field configuration. It is shown by numerical integration of the equation of motion that the system is generally nonintegrable and that the particle motion can be classified into three distinct types of orbits: bounded integrable orbits, unbounded stochastic orbits, and unbounded transient orbits. It is also shown that different regions of the phase space exhibit qualitatively different responses to external influences. The concept of 'differential memory' in single-particle distributions is proposed. Physical implications for the dynamical properties of the magnetotail plasmas and the possible generation of non-Maxwellian features in the distribution functions are discussed.

Orbital fractures: a review

Directory of Open Access Journals (Sweden)

Jeffrey M Joseph

2011-01-01

Full Text Available Jeffrey M Joseph, Ioannis P GlavasDivision of Ophthalmic Plastic and Reconstructive Surgery, Department of Ophthalmology, School of Medicine, New York University, New York, NY, USA; Manhattan Eye, Ear, and Throat Hospital, New York, NY, USAAbstract: This review of orbital fractures has three goals: 1 to understand the clinically relevant orbital anatomy with regard to periorbital trauma and orbital fractures, 2 to explain how to assess and examine a patient after periorbital trauma, and 3 to understand the medical and surgical management of orbital fractures. The article aims to summarize the evaluation and management of commonly encountered orbital fractures from the ophthalmologic perspective and to provide an overview for all practicing ophthalmologists and ophthalmologists in training.Keywords: orbit, trauma, fracture, orbital floor, medial wall, zygomatic, zygomatic complex, zmc fracture, zygomaticomaxillary complex fractures 

Matrix completion by deep matrix factorization.

Science.gov (United States)

Fan, Jicong; Cheng, Jieyu

2018-02-01

Conventional methods of matrix completion are linear methods that are not effective in handling data of nonlinear structures. Recently a few researchers attempted to incorporate nonlinear techniques into matrix completion but there still exists considerable limitations. In this paper, a novel method called deep matrix factorization (DMF) is proposed for nonlinear matrix completion. Different from conventional matrix completion methods that are based on linear latent variable models, DMF is on the basis of a nonlinear latent variable model. DMF is formulated as a deep-structure neural network, in which the inputs are the low-dimensional unknown latent variables and the outputs are the partially observed variables. In DMF, the inputs and the parameters of the multilayer neural network are simultaneously optimized to minimize the reconstruction errors for the observed entries. Then the missing entries can be readily recovered by propagating the latent variables to the output layer. DMF is compared with state-of-the-art methods of linear and nonlinear matrix completion in the tasks of toy matrix completion, image inpainting and collaborative filtering. The experimental results verify that DMF is able to provide higher matrix completion accuracy than existing methods do and DMF is applicable to large matrices. Copyright © 2017 Elsevier Ltd. All rights reserved.

Hyperfine electron-nuclear interactions in the frame of the Density Functional and of the Density Matrix Methods

International Nuclear Information System (INIS)

Pavlov, R.L.; Pavlov, L.I.; Raychev, P.P.; Garistov, V.P.; Dimitrova-Ivanovich, M.

2002-01-01

The matrix elements and expectation values of the hyperfine interaction operators are presented in a form suitable for numerical implementation in density matrix methods. The electron-nuclear spin-spin (dipolar and contact) interactions are considered, as well as the interaction between nuclear spin and electron-orbital motions. These interactions from the effective Breit-Pauli Hamiltonian determine the hyperfine structure in ESR spectra and contribute to chemical shifts in NMR. Applying the Wigner-Eckart theorem in the irreducible tensor-operator technique and the spin-space separation scheme, the matrix elements and expectation values of these relativistic corrections are expressed in analytical form. The final results are presented as products, or sums of products, of factors determined by the spin and (or) angular momentum symmetry and a spatial part determined by the action of the symmetrized tensor-operators on the normalized matrix or function of the spin or charge distribution.

Classical-limit S-matrix for heavy ion scattering

International Nuclear Information System (INIS)

Donangelo, R.J.

1977-01-01

An integral representation for the classical limit of the quantum mechanical S-matrix is developed and applied to heavy-ion Coulomb excitation and Coulomb-nuclear interference. The method combines the quantum principle of superposition with exact classical dynamics to describe the projectile-target system. A detailed consideration of the classical trajectories and of the dimensionless parameters that characterize the system is carried out. The results are compared, where possible, to exact quantum mechanical calculations and to conventional semiclassical calculations. It is found that in the case of backscattering the classical limit S-matrix method is able to almost exactly reproduce the quantum-mechanical S-matrix elements, and therefore the transition probabilities, even for projectiles as light as protons. The results also suggest that this approach should be a better approximation for heavy-ion multiple Coulomb excitation than earlier semiclassical methods, due to a more accurate description of the classical orbits in the electromagnetic field of the target nucleus. Calculations using this method indicate that the rotational excitation probabilities in the Coulomb-nuclear interference region should be very sensitive to the details of the potential at the surface of the nucleus, suggesting that heavy-ion rotational excitation could constitute a sensitive probe of the nuclear potential in this region. The application to other problems as well as the present limits of applicability of the formalism are also discussed

Peripheral orbit model

CERN Document Server

Hara, Yasuo

1975-01-01

Peripheral orbit model, in which an incoming hadron is assumed to revolve in a peripheral orbit around a target hadron, is discussed. The non-diffractive parts of two-body reaction amplitudes of hadrons are expressed in terms of the radius, width an absorptivity of the orbit. The radius of the orbit is about 1 fm and the width of the orbit is determined by the range of the interaction between the hadrons. The model reproduces all available experimental data on differential cross-sections and polarizations of $K^{-}p\\to K^{-}p$ and $\\bar K^{\\circ}n$ reactions for all angles successfully. This contribution is not included in the proceedings since it will appear in Progress of Theoretical Physics Vol. 51 (1974) No 2. Any person interested in the subject may apply for reprints to the author.

Orbital transport

International Nuclear Information System (INIS)

Oertel, H. Jr.; Koerner, H.

1993-01-01

The Third Aerospace Symposium in Braunschweig presented, for the first time, the possibility of bringing together the classical disciplines of aerospace engineering and the natural science disciplines of meteorology and air chemistry in a european setting. In this way, aspects of environmental impact on the atmosphere could be examined quantitatively. An essential finding of the european conference, is the unrestricted agreement of the experts that the given launch frequencies of the present orbital transport result in a negligible amount of pollutants being released in the atmosphere. The symposium does, however, call attention to the increasing need to consider the effect of orbital and atmospheric environmental impact of a future increase in launch frequencies of orbital transport in connection with future space stations. The Third Aerospace Symposium, 'Orbital Transport, Technical, Meteorological and Chemical Aspects', constituted a first forum of discussion for engineers and scientists. Questions of new orbital transport technologies and their environmental impact were to be discussed towards a first consensus. Through the 34 reports and articles, the general problems of space transportation and environmental protection were addressed, as well as particular aspects of high temperatures during reentry in the atmosphere of the earth, precision navigation of flight vehicles or flow behavior and air chemistry in the stratosphere. (orig./CT). 342 figs

Orbital apex syndrome associated with fractures of the inferomedial orbital wall

Directory of Open Access Journals (Sweden)

Sugamata A

2013-03-01

Full Text Available Akira SugamataDepartment of Plastic and Reconstructive Surgery, Tokyo Medical University Hachioji Medical Center, Tokyo, JapanAbstract: Although trauma is one of the main causes of orbital apex syndrome (OAS, reports of OAS associated with orbital fractures are relatively rare. We recently treated two patients who sustained severe visual impairment with damage to multiple cranial nerves (third to sixth associated with inferomedial orbital wall fractures. In these patients, posterior movement of the globe caused neuropathy of the cranial and optic nerves by posterior globe edema and hemorrhage, or direct impact between the globe and wall, which might then have induced OAS in the cases described in this report. Steroid therapy was unsuccessful for optic neuropathy due to the delay between injury and administration. When treating patients with inferomedial orbital blowout fractures due to globe-to-wall contact, it is necessary to routinely assess and monitor visual acuity since there may be a delay between the injury and OAS onset.Keywords: orbital apex syndrome, orbital fracture, blowout fracture, optic nerve, globe-to-wall contact mechanism

A response matrix method for slab-geometry discrete ordinates adjoint calculations in energy-dependent source-detector problems

Energy Technology Data Exchange (ETDEWEB)

Mansur, Ralph S.; Moura, Carlos A., E-mail: ralph@ime.uerj.br, E-mail: demoura@ime.uerj.br [Universidade do Estado do Rio de Janeiro (UERJ), RJ (Brazil). Departamento de Engenharia Mecanica; Barros, Ricardo C., E-mail: rcbarros@pq.cnpq.br [Universidade do Estado do Rio de Janeiro (UERJ), Nova Friburgo, RJ (Brazil). Departamento de Modelagem Computacional

2017-07-01

Presented here is an application of the Response Matrix (RM) method for adjoint discrete ordinates (S{sub N}) problems in slab geometry applied to energy-dependent source-detector problems. The adjoint RM method is free from spatial truncation errors, as it generates numerical results for the adjoint angular fluxes in multilayer slabs that agree with the numerical values obtained from the analytical solution of the energy multigroup adjoint SN equations. Numerical results are given for two typical source-detector problems to illustrate the accuracy and the efficiency of the offered RM computer code. (author)

Performance Comparison of Different System Identification Algorithms for FACET and ATF2

CERN Document Server

Pfingstner, J; Schulte, D

2013-01-01

Good system knowledge is an essential ingredient for the operation of modern accelerator facilities. For example, beam-based alignment algorithms and orbit feedbacks rely strongly on a precise measurement of the orbit response matrix. The quality of the measurement of this matrix can be improved over time by statistically combining the effects of small system excitations with the help of system identification algorithms. These small excitations can be applied in a parasitic mode without stopping the accelerator operation (on-line). In this work, different system identification algorithms are used in simulation studies for the response matrix measurement at ATF2. The results for ATF2 are finally compared with the results for FACET, latter originating from an earlier work.

Influence of a superconducting lead on orbital entanglement production in chaotic cavities

International Nuclear Information System (INIS)

Rodriguez-Perez, Sergio; Novaes, Marcel

2015-01-01

We study orbital entanglement production in a chaotic cavity connected to four single-channel normal metal leads and one superconducting lead, assuming the presence of time-reversal symmetry and within a random matrix theory approach. The scattered state of two incident electrons is written as the superposition of several two-outgoing quasi-particle components, four of which are orbitally entangled in a left-right bipartition. We calculate numerically the mean value of the squared norm of each entangled component, as functions of the number of channels in the superconducting lead. Its behavior is explained as resulting from the proximity effect. We also study statistically the amount of entanglement carried by each pair of outgoing quasi-particles. When the influence of the superconductor is more intense, the device works as an entangler of electron-hole pairs, and the average entanglement is found to be considerably larger than that obtained without the superconducting lead. (author)

Influence of a superconducting lead on orbital entanglement production in chaotic cavities

Energy Technology Data Exchange (ETDEWEB)

Rodriguez-Perez, Sergio [Universidade Federal do Rio Grande do Norte (UFRN), Natal, RN (Brazil). Escola de Ciencias e Tecnologia; Novaes, Marcel, E-mail: sergio.rodriguez@ect.ufrn.br [Universidade Federal de Uberlandia (UFU), MG (Brazil). Instituto de Fisica

2015-10-15

We study orbital entanglement production in a chaotic cavity connected to four single-channel normal metal leads and one superconducting lead, assuming the presence of time-reversal symmetry and within a random matrix theory approach. The scattered state of two incident electrons is written as the superposition of several two-outgoing quasi-particle components, four of which are orbitally entangled in a left-right bipartition. We calculate numerically the mean value of the squared norm of each entangled component, as functions of the number of channels in the superconducting lead. Its behavior is explained as resulting from the proximity effect. We also study statistically the amount of entanglement carried by each pair of outgoing quasi-particles. When the influence of the superconductor is more intense, the device works as an entangler of electron-hole pairs, and the average entanglement is found to be considerably larger than that obtained without the superconducting lead. (author)

Induced Orbital Paramagnetism and Paratropism in Closed-Shell Molecules

Science.gov (United States)

Pelloni, Stefano; Lazzeretti, Paolo; Zanasi, Riccardo

2009-07-01

Three-dimensional models of the quantum-mechanical current density induced by a uniform magnetic field in the electron cloud have been obtained for closed-shell systems BeH-, BH, and CH+, characterized by induced orbital paramagnetism, and in planar unsaturated hydrocarbons C4H4 and clamped C8H8, exhibiting π paramagnetism. It is shown that, even for these paramagnetic systems, the paramagnetic contributions to magnetic susceptibilities and nuclear magnetic shielding, customarily taken into account in perturbation theory approaches, can formally be eliminated via the procedure of continuous transformation of the origin of the current density-paramagnetic zero. The definition of magnetic response properties can therefore be recast as a sum of two formally "diamagnetic" terms for any molecule, including systems showing strong induced orbital paramagnetism. It is shown that the paramagnetism in the compounds studied arises from the nodal topology of the electronic wave function. In particular, paratropic vortices circulate about stagnation lines at the intersection of nodal surfaces of the highest-occupied zero-order molecular orbital and corresponding first-order orbital.

On the atmospheric drag in orbit determination for low Earth orbit

Science.gov (United States)

Tang, Jingshi; Liu, Lin; Miao, Manqian

2012-07-01

The atmosphere model is always a major limitation for low Earth orbit (LEO) in orbit prediction and determination. The accelerometer can work around the non-gravitational perturbations in orbit determination, but it helps little to improve the atmosphere model or to predict the orbit. For certain satellites, there may be some specific software to handle the orbit problem. This solution can improve the orbit accuracy for both prediction and determination, yet it always contains empirical terms and is exclusive for certain satellites. This report introduces a simple way to handle the atmosphere drag for LEO, which does not depend on instantaneous atmosphere conditions and improves accuracy of predicted orbit. This approach, which is based on mean atmospheric density, is supported by two reasons. One is that although instantaneous atmospheric density is very complicated with time and height, the major pattern is determined by the exponential variation caused by hydrostatic equilibrium and periodic variation caused by solar radiation. The mean density can include the major variations while neglect other minor details. The other reason is that the predicted orbit is mathematically the result from integral and the really determinant factor is the mean density instead of instantaneous density for every time and spot. Using the mean atmospheric density, which is mainly determined by F10.7 solar flux and geomagnetic index, can be combined into an overall parameter B^{*} = C_{D}(S/m)ρ_{p_{0}}. The combined parameter contains several less accurate parameters and can be corrected during orbit determination. This approach has been confirmed in various LEO computations and an example is given below using Tiangong-1 spacecraft. Precise orbit determination (POD) is done using one-day GPS positioning data without any accurate a-priori knowledge on spacecraft or atmosphere conditions. Using the corrected initial state vector of the spacecraft and the parameter B^* from POD, the

Space station orbit maintenance

Science.gov (United States)

Kaplan, D. I.; Jones, R. M.

1983-01-01

The orbit maintenance problem is examined for two low-earth-orbiting space station concepts - the large, manned Space Operations Center (SOC) and the smaller, unmanned Science and Applications Space Platform (SASP). Atmospheric drag forces are calculated, and circular orbit altitudes are selected to assure a 90 day decay period in the event of catastrophic propulsion system failure. Several thrusting strategies for orbit maintenance are discussed. Various chemical and electric propulsion systems for orbit maintenance are compared on the basis of propellant resupply requirements, power requirements, Shuttle launch costs, and technology readiness.

SynergyFinder: a web application for analyzing drug combination dose-response matrix data.

Science.gov (United States)

Ianevski, Aleksandr; He, Liye; Aittokallio, Tero; Tang, Jing

2017-08-01

Rational design of drug combinations has become a promising strategy to tackle the drug sensitivity and resistance problem in cancer treatment. To systematically evaluate the pre-clinical significance of pairwise drug combinations, functional screening assays that probe combination effects in a dose-response matrix assay are commonly used. To facilitate the analysis of such drug combination experiments, we implemented a web application that uses key functions of R-package SynergyFinder, and provides not only the flexibility of using multiple synergy scoring models, but also a user-friendly interface for visualizing the drug combination landscapes in an interactive manner. The SynergyFinder web application is freely accessible at https://synergyfinder.fimm.fi ; The R-package and its source-code are freely available at http://bioconductor.org/packages/release/bioc/html/synergyfinder.html . jing.tang@helsinki.fi. © The Author(s) 2017. Published by Oxford University Press.

Regulation of extracellular matrix vesicles via rapid responses to steroid hormones during endochondral bone formation.

Science.gov (United States)

Asmussen, Niels; Lin, Zhao; McClure, Michael J; Schwartz, Zvi; Boyan, Barbara D

2017-12-09

Endochondral bone formation is a precise and highly ordered process whose exact regulatory framework is still being elucidated. Multiple regulatory pathways are known to be involved. In some cases, regulation impacts gene expression, resulting in changes in chondrocyte phenotypic expression and extracellular matrix synthesis. Rapid regulatory mechanisms are also involved, resulting in release of enzymes, factors and micro RNAs stored in extracellular matrisomes called matrix vesicles. Vitamin D metabolites modulate endochondral development via both genomic and rapid membrane-associated signaling pathways. 1α,25-dihydroxyvitamin D3 [1α,25(OH) 2 D 3 ] acts through the vitamin D receptor (VDR) and a membrane associated receptor, protein disulfide isomerase A3 (PDIA3). 24R,25-dihydroxyvitamin D3 [24R,25(OH) 2 D 3 ] affects primarily chondrocytes in the resting zone (RC) of the growth plate, whereas 1α,25(OH) 2 D 3 affects cells in the prehypertrophic and upper hypertrophic cell zones (GC). This includes genomically directing the cells to produce matrix vesicles with zone specific characteristics. In addition, vitamin D metabolites produced by the cells interact directly with the matrix vesicle membrane via rapid signal transduction pathways, modulating their activity in the matrix. The matrix vesicle payload is able to rapidly impact the extracellular matrix via matrix processing enzymes as well as providing a feedback mechanism to the cells themselves via the contained micro RNAs. Copyright © 2017. Published by Elsevier Inc.

Orbit error characteristic and distribution of TLE using CHAMP orbit data

Science.gov (United States)

Xu, Xiao-li; Xiong, Yong-qing

2018-02-01

Space object orbital covariance data is required for collision risk assessments, but publicly accessible two line element (TLE) data does not provide orbital error information. This paper compared historical TLE data and GPS precision ephemerides of CHAMP to assess TLE orbit accuracy from 2002 to 2008, inclusive. TLE error spatial variations with longitude and latitude were calculated to analyze error characteristics and distribution. The results indicate that TLE orbit data are systematically biased from the limited SGP4 model. The biases can reach the level of kilometers, and the sign and magnitude are correlate significantly with longitude.

An Orbit Propagation Software for Mars Orbiting Spacecraft

Directory of Open Access Journals (Sweden)

Young-Joo Song

2004-12-01

Full Text Available An orbit propagation software for the Mars orbiting spacecraft has been developed and verified in preparations for the future Korean Mars missions. Dynamic model for Mars orbiting spacecraft has been studied, and Mars centered coordinate systems are utilized to express spacecraft state vectors. Coordinate corrections to the Mars centered coordinate system have been made to adjust the effects caused by Mars precession and nutation. After spacecraft enters Sphere of Influence (SOI of the Mars, the spacecraft experiences various perturbation effects as it approaches to Mars. Every possible perturbation effect is considered during integrations of spacecraft state vectors. The Mars50c gravity field model and the Mars-GRAM 2001 model are used to compute perturbation effects due to Mars gravity field and Mars atmospheric drag, respectively. To compute exact locations of other planets, JPL's DE405 ephemerides are used. Phobos and Deimos's ephemeris are computed using analytical method because their informations are not released with DE405. Mars Global Surveyor's mapping orbital data are used to verify the developed propagator performances. After one Martian day propagation (12 orbital periods, the results show about maximum ±5 meter errors, in every position state components(radial, cross-track and along-track, when compared to these from the Astrogator propagation in the Satellite Tool Kit. This result shows high reliability of the developed software which can be used to design near Mars missions for Korea, in future.

Burn Delay Analysis of the Lunar Orbit Insertion for Korea Pathfinder Lunar Orbiter

Science.gov (United States)

Bae, Jonghee; Song, Young-Joo; Kim, Young-Rok; Kim, Bangyeop

2017-12-01

The first Korea lunar orbiter, Korea Pathfinder Lunar Orbiter (KPLO), has been in development since 2016. After launch, the KPLO will execute several maneuvers to enter into the lunar mission orbit, and will then perform lunar science missions for one year. Among these maneuvers, the lunar orbit insertion (LOI) is the most critical maneuver because the KPLO will experience an extreme velocity change in the presence of the Moon’s gravitational pull. However, the lunar orbiter may have a delayed LOI burn during operation due to hardware limitations and telemetry delays. This delayed burn could occur in different captured lunar orbits; in the worst case, the KPLO could fly away from the Moon. Therefore, in this study, the burn delay for the first LOI maneuver is analyzed to successfully enter the desired lunar orbit. Numerical simulations are performed to evaluate the difference between the desired and delayed lunar orbits due to a burn delay in the LOI maneuver. Based on this analysis, critical factors in the LOI maneuver, the periselene altitude and orbit period, are significantly changed and an additional delta-V in the second LOI maneuver is required as the delay burn interval increases to 10 min from the planned maneuver epoch.

Using matrix organization to manage health care delivery organizations.

Science.gov (United States)

Allcorn, S

1990-01-01

Matrix organization can provide health care organization managers enhanced information processing, faster response times, and more flexibility to cope with greater organization complexity and rapidly changing operating environments. A review of the literature informed by work experience reveals that the use of matrix organization creates hard-to-manage ambiguity and balances of power in addition to providing positive benefits for health care organization managers. Solutions to matrix operating problems generally rely on the use of superior information and decision support systems and extensive staff training to develop attitudes and behavior consistent with the more collegial matrix organization culture. Further improvement in understanding the suitability of matrix organization for managing health care delivery organizations will involve appreciating the impact of partial implementation of matrix organization, temporary versus permanent uses of matrix organization, and the impact of the ambiguity created by dual lines of authority upon the exercise of power and authority.

DBDA as a Novel Matrix for the Analyses of Small Molecules and Quantification of Fatty Acids by Negative Ion MALDI-TOF MS

Science.gov (United States)

Ling, Ling; Li, Ying; Wang, Sheng; Guo, Liming; Xiao, Chunsheng; Chen, Xuesi; Guo, Xinhua

2018-01-01

Matrix interference ions in low mass range has always been a concern when using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) to analyze small molecules (fatty acids without matrix interference appeared in the mass spectra and the limit of detection (LOD) reached 0.3 fmol. DBDA also has great performance towards other small molecules such as amino acids, peptides, and nucleotide. Furthermore, with this novel matrix, the free fatty acids in serum were quantitatively analyzed based on the correlation curves with correlation coefficient of 0.99. In addition, UV-Vis experiments and molecular orbital calculations were performed to explore mechanism about DBDA used as matrix in the negative ion mode. The present work shows that the DBDA matrix is a highly sensitive matrix with few interference ions for analysis of small molecules. Meanwhile, DBDA is able to precisely quantify the fatty acids in real biological samples. [Figure not available: see fulltext.

Use of density functional theory orbitals in the GVVPT2 variant of second-order multistate multireference perturbation theory.

Science.gov (United States)

Hoffmann, Mark R; Helgaker, Trygve

2015-03-05

A new variation of the second-order generalized van Vleck perturbation theory (GVVPT2) for molecular electronic structure is suggested. In contrast to the established procedure, in which CASSCF or MCSCF orbitals are first obtained and subsequently used to define a many-electron model (or reference) space, the use of an orbital space obtained from the local density approximation (LDA) variant of density functional theory is considered. Through a final, noniterative diagonalization of an average Fock matrix within orbital subspaces, quasicanonical orbitals that are otherwise indistinguishable from quasicanonical orbitals obtained from a CASSCF or MCSCF calculation are obtained. Consequently, all advantages of the GVVPT2 method are retained, including use of macroconfigurations to define incomplete active spaces and rigorous avoidance of intruder states. The suggested variant is vetted on three well-known model problems: the symmetric stretching of the O-H bonds in water, the dissociation of N2, and the stretching of ground and excited states C2 to more than twice the equilibrium bond length of the ground state. It is observed that the LDA-based GVVPT2 calculations yield good results, of comparable quality to conventional CASSCF-based calculations. This is true even for the C2 model problem, in which the orbital space for each state was defined by the LDA orbitals. These results suggest that GVVPT2 can be applied to much larger problems than previously accessible.

GLONASS Orbits in Teqc: Methodology and Future Extension for Using SP3 Orbits

Science.gov (United States)

Estey, L.; Wier, S.

2011-12-01

UNAVCO's teqc software package provides translation of a wide variety of GNSS receiver formats, metadata editing (either during translation to RINEX or on existing RINEX files), time-windowing and epoch decimation editing, and quality check (qc) analysis. Teqc is used extensively in GNSS pre-processing, and is designed to handle mixed satellite constellations, such as GPS, GLONASS, Galileo, and SBAS. The latest release of teqc adds GLONASS orbit calculations using GLONASS broadcast navigation messages, read from RINEX file format, during qc. The ephemerides for each GLONASS SV have time and orbit position in Earth-centered, Earth-fixed x, y, and z coordinates. Following Schenewerk [2003], we use trigonometric interpolation, essentially a fit of a partial sum of the Fourier series for each time-varying cartesian orbital component, allowing estimates of orbit positions at most GLONASS observation times. Tests show the interpolated GLONASS orbits made from the broadcast messages diverge from final orbits little more than the same differences using GPS orbits computed from their broadcast messages. Since GLONASS ephemerides do not use Keplerian orbital elements, GLONASS SV orbits can only be interpolated using this method for time intervals when an adequate sequence of ephemerides are available. For typical daily navigation messages collected at a single sit, when a GLONASS SV is in view less than three hours, that SV's signals are generally not used by teqc due to less precise orbit positions. Teqc quality control including SV position can now use GPS alone, GLONASS alone, or the joint solution. Future work will extend teqc to use SP3 format files, such as the IGS final orbit files, and SBAS data, which have broadcast ephemerides with elements similar to GLONASS.

Reduction of Inflammatory Responses and Enhancement of Extracellular Matrix Formation by Vanillin-Incorporated Poly(Lactic-co-Glycolic Acid) Scaffolds

OpenAIRE

Lee, Yujung; Kwon, Jeongil; Khang, Gilson; Lee, Dongwon

2012-01-01

Vanillin is one of the major components of vanilla, a commonly used flavoring agent and preservative and is known to exert potent antioxidant and anti-inflammatory activities. In this work, vanillin-incorporated poly(lactic-co-glycolic acid) (PLGA) films and scaffolds were fabricated to evaluate the effects of vanillin on the inflammatory responses and extracellular matrix (ECM) formation in vitro and in vivo. The incorporation of vanillin to PLGA films induced hydrophilic nature, resulting i...

Nontraumatic orbital roof encephalocele.

Science.gov (United States)

Hoang, Amber; Maugans, Todd; Ngo, Thang; Ikeda, Jamie

2017-02-01

Intraorbital meningoencephaloceles occur most commonly as a complication of traumatic orbital roof fractures. Nontraumatic congenital orbital meningoncephaloceles are very rare, with most secondary to destructive processes affecting the orbit and primary skull defects. Treatment for intraorbital meningoencephaloceles is surgical repair, involving the excision of herniated brain parenchyma and meninges and reconstruction of the osseous defect. Most congenital lesions present in infancy with obvious globe and orbital deformities; we report an orbital meningoencephalocele in a 3-year-old girl who presented with ptosis. Copyright © 2017 American Association for Pediatric Ophthalmology and Strabismus. Published by Elsevier Inc. All rights reserved.

Effect of cubic Dresselhaus interaction on the longitudinal optical conductivity of a spin-orbit coupled system

Science.gov (United States)

Cruz, Elmer; López-Bastidas, Catalina; Maytorena, Jesús A.

2018-03-01

We investigate the effect of the oft-neglected cubic terms of the Dresselhaus spin-orbit coupling on the longitudinal current response of a two-dimensional electron gas with both Rashba and linear Dresselhaus interactions. For a quantum well grown in the [001] direction, the changes caused by these nonlinear-in-momentum terms on the absorption spectrum become more notable under SU(2) symmetry conditions, when the Rashba and linear Dresselhaus coupling strengths are tuned to be equal. The longitudinal optical response no longer vanishes then and shows a strong dependence on the direction of the externally applied electric field, giving a signature of the relative size of several spin-orbit contributions. This anisotropic response arises from the nonisotropic splitting of the spin states induced by the interplay of Rashba and Dresselhaus couplings. However, the presence of cubic terms introduces characteristic spectral features and can modify the overall shape of the spectra for some values of the relative sizes of the spin-orbit parameters. We compare this behavior to the case of a sample with [110] crystal orientation which, under conditions of spin-preserving symmetry, has a collinear spin-orbit vector field that leads to vanishing conductivity, even in the presence of cubic terms. In addition to the control through the driven frequency or electrical gating, such a directional aspect of the current response suggests new ways of manipulation and supports the use of interband optics as a sensitive probe of spin-orbit mechanisms in semiconductor spintronics.

Fibre-Matrix Interaction in Soft Tissue

International Nuclear Information System (INIS)

Guo, Zaoyang

2010-01-01

Although the mechanical behaviour of soft tissue has been extensively studied, the interaction between the collagen fibres and the ground matrix has not been well understood and is therefore ignored by most constitutive models of soft tissue. In this paper, the human annulus fibrosus is used as an example and the potential fibre-matrix interaction is identified by careful investigation of the experimental results of biaxial and uniaxial testing of the human annulus fibrosus. First, the uniaxial testing result of the HAF along the axial direction is analysed and it is shown that the mechanical behaviour of the ground matrix can be well simulated by the incompressible neo-Hookean model when the collagen fibres are all under contraction. If the collagen fibres are stretched, the response of the ground matrix can still be described by the incompressible neo-Hookean model, but the effective stiffness of the matrix depends on the fibre stretch ratio. This stiffness can be more than 10 times larger than the one obtained with collagen fibres under contraction. This phenomenon can only be explained by the fibre-matrix interaction. Furthermore, we find that the physical interpretation of this interaction includes the inhomogeneity of the soft tissue and the fibre orientation dispersion. The dependence of the tangent stiffness of the matrix on the first invariant of the deformation tensor can also be explained by the fibre orientation dispersion. The significant effect of the fibre-matrix interaction strain energy on mechanical behaviour of the soft tissue is also illustrated by comparing some simulation results.

E-Orbit Functions

Directory of Open Access Journals (Sweden)

Jiri Patera

2008-01-01

Full Text Available We review and further develop the theory of $E$-orbit functions. They are functions on the Euclidean space $E_n$ obtained from the multivariate exponential function by symmetrization by means of an even part $W_{e}$ of a Weyl group $W$, corresponding to a Coxeter-Dynkin diagram. Properties of such functions are described. They are closely related to symmetric and antisymmetric orbit functions which are received from exponential functions by symmetrization and antisymmetrization procedure by means of a Weyl group $W$. The $E$-orbit functions, determined by integral parameters, are invariant withrespect to even part $W^{aff}_{e}$ of the affine Weyl group corresponding to $W$. The $E$-orbit functions determine a symmetrized Fourier transform, where these functions serve as a kernel of the transform. They also determine a transform on a finite set of points of the fundamental domain $F^{e}$ of the group $W^{aff}_{e}$ (the discrete $E$-orbit function transform.

Application of consistent fluid added mass matrix to core seismic

International Nuclear Information System (INIS)

Koo, K. H.; Lee, J. H.

2003-01-01

In this paper, the application algorithm of a consistent fluid added mass matrix including the coupling terms to the core seismic analysis is developed and installed at SAC-CORE3.0 code. As an example, we assumed the 7-hexagon system of the LMR core and carried out the vibration modal analysis and the nonlinear time history seismic response analysis using SAC-CORE3.0. Used consistent fluid added mass matrix is obtained by using the finite element program of the FAMD(Fluid Added Mass and Damping) code. From the results of the vibration modal analysis, the core duct assemblies reveal strongly coupled vibration modes, which are so different from the case of in-air condition. From the results of the time history seismic analysis, it was verified that the effects of the coupled terms of the consistent fluid added mass matrix are significant in impact responses and the dynamic responses

H4: A challenging system for natural orbital functional approximations

International Nuclear Information System (INIS)

Ramos-Cordoba, Eloy; Lopez, Xabier; Piris, Mario; Matito, Eduard

2015-01-01

The correct description of nondynamic correlation by electronic structure methods not belonging to the multireference family is a challenging issue. The transition of D 2h to D 4h symmetry in H 4 molecule is among the most simple archetypal examples to illustrate the consequences of missing nondynamic correlation effects. The resurgence of interest in density matrix functional methods has brought several new methods including the family of Piris Natural Orbital Functionals (PNOF). In this work, we compare PNOF5 and PNOF6, which include nondynamic electron correlation effects to some extent, with other standard ab initio methods in the H 4 D 4h /D 2h potential energy surface (PES). Thus far, the wrongful behavior of single-reference methods at the D 2h –D 4h transition of H 4 has been attributed to wrong account of nondynamic correlation effects, whereas in geminal-based approaches, it has been assigned to a wrong coupling of spins and the localized nature of the orbitals. We will show that actually interpair nondynamic correlation is the key to a cusp-free qualitatively correct description of H 4 PES. By introducing interpair nondynamic correlation, PNOF6 is shown to avoid cusps and provide the correct smooth PES features at distances close to the equilibrium, total and local spin properties along with the correct electron delocalization, as reflected by natural orbitals and multicenter delocalization indices

H4: A challenging system for natural orbital functional approximations

Science.gov (United States)

Ramos-Cordoba, Eloy; Lopez, Xabier; Piris, Mario; Matito, Eduard

2015-10-01

The correct description of nondynamic correlation by electronic structure methods not belonging to the multireference family is a challenging issue. The transition of D2h to D4h symmetry in H4 molecule is among the most simple archetypal examples to illustrate the consequences of missing nondynamic correlation effects. The resurgence of interest in density matrix functional methods has brought several new methods including the family of Piris Natural Orbital Functionals (PNOF). In this work, we compare PNOF5 and PNOF6, which include nondynamic electron correlation effects to some extent, with other standard ab initio methods in the H4 D4h/D2h potential energy surface (PES). Thus far, the wrongful behavior of single-reference methods at the D2h-D4h transition of H4 has been attributed to wrong account of nondynamic correlation effects, whereas in geminal-based approaches, it has been assigned to a wrong coupling of spins and the localized nature of the orbitals. We will show that actually interpair nondynamic correlation is the key to a cusp-free qualitatively correct description of H4 PES. By introducing interpair nondynamic correlation, PNOF6 is shown to avoid cusps and provide the correct smooth PES features at distances close to the equilibrium, total and local spin properties along with the correct electron delocalization, as reflected by natural orbitals and multicenter delocalization indices.

Congenital orbital encephalocele, orbital dystopia, and exophthalmos.

Science.gov (United States)

Hwang, Kun; Kim, Han Joon

2012-07-01

We present here an exceedingly rare variant of a nonmidline basal encephalocele of the spheno-orbital type, and this was accompanied with orbital dystopia in a 56-year-old man. On examination, his left eye was located more inferolaterally than his right eye, and the patient said this had been this way since his birth. The protrusion of his left eye was aggravated when he is tired. His naked visual acuity was 0.7/0.3, and the ocular pressure was 14/12 mm Hg. The exophthalmometry was 10/14 to 16 mm. His eyeball motion was not restricted, yet diplopia was present in all directions. The distance from the midline to the medial canthus was 20/15 mm. The distance from the midline to the midpupillary line was 35/22 mm. The vertical dimension of the palpebral fissure was 12/9 mm. The height difference of the upper eyelid margin was 11 mm, and the height difference of the lower eyelid margin was 8 mm. Facial computed tomography and magnetic resonance imaging showed left sphenoid wing hypoplasia and herniation of the left anterior temporal pole and dura mater into the orbit, and this resulted into left exophthalmos and encephalomalacia in the left anterior temporal pole. To the best of our knowledge, our case is the second case of basal encephalocele and orbital dystopia.

Measurement of orbital volume by computed tomography. Especially on the growth of orbit

Energy Technology Data Exchange (ETDEWEB)

Furuta, Minoru [Fukushima Medical Coll. (Japan)

2000-10-01

Using reconstructed X-ray computed tomography (CT) images of serial coronal sections, we measured the orbital volume and studied its changes with age. The subjects consisted of 109 patients (74 males, 35 females) who had undergone X-ray CT. After the reproducibility of orbital volume measurements and laterality in individuals were confirmed, the relation between the orbital volume and the age, sex, weight, and interlateral orbital rim distance were examined. The difference between two measurements in the same patients was 0.4% for measured volume, which showed the reproducibility of this measurement to be good. The laterality in individuals was 0.06 cm{sup 3}: this difference was very small and not significant. The orbital volume showed no unbalance between the right and left at any stage of growth. Both the height and the interlateral orbital rim distance had a strong correlation with the orbital volume. Referring to the relation between age and orbital volume, a strong correlation with an almost identical approximate equation was obtained for both sexes under 12 years of age. Presumably, the rapid growth of the orbit comes to an end by 15 years of age in males and 11 years in females. This means that more than 95% growth of adults has already been completed in the first half of the teens. The mean orbital volume in adult Japanese is 23.6{+-}2.0 (mean{+-}standard deviation) cm{sup 3} in males and 20.9{+-}1.3 cm{sup 3} in females. (author)

Measurement of orbital volume by computed tomography. Especially on the growth of orbit

International Nuclear Information System (INIS)

Furuta, Minoru

2000-01-01

Using reconstructed X-ray computed tomography (CT) images of serial coronal sections, we measured the orbital volume and studied its changes with age. The subjects consisted of 109 patients (74 males, 35 females) who had undergone X-ray CT. After the reproducibility of orbital volume measurements and laterality in individuals were confirmed, the relation between the orbital volume and the age, sex, weight, and interlateral orbital rim distance were examined. The difference between two measurements in the same patients was 0.4% for measured volume, which showed the reproducibility of this measurement to be good. The laterality in individuals was 0.06 cm 3 : this difference was very small and not significant. The orbital volume showed no unbalance between the right and left at any stage of growth. Both the height and the interlateral orbital rim distance had a strong correlation with the orbital volume. Referring to the relation between age and orbital volume, a strong correlation with an almost identical approximate equation was obtained for both sexes under 12 years of age. Presumably, the rapid growth of the orbit comes to an end by 15 years of age in males and 11 years in females. This means that more than 95% growth of adults has already been completed in the first half of the teens. The mean orbital volume in adult Japanese is 23.6±2.0 (mean±standard deviation) cm 3 in males and 20.9±1.3 cm 3 in females. (author)

Low-Cost 3D Printing Orbital Implant Templates in Secondary Orbital Reconstructions.

Science.gov (United States)

Callahan, Alison B; Campbell, Ashley A; Petris, Carisa; Kazim, Michael

Despite its increasing use in craniofacial reconstructions, three-dimensional (3D) printing of customized orbital implants has not been widely adopted. Limitations include the cost of 3D printers able to print in a biocompatible material suitable for implantation in the orbit and the breadth of available implant materials. The authors report the technique of low-cost 3D printing of orbital implant templates used in complex, often secondary, orbital reconstructions. A retrospective case series of 5 orbital reconstructions utilizing a technique of 3D printed orbital implant templates is presented. Each patient's Digital Imaging and Communications in Medicine data were uploaded and processed to create 3D renderings upon which a customized implant was designed and sent electronically to printers open for student use at our affiliated institutions. The mock implants were sterilized and used intraoperatively as a stencil and mold. The final implant material was chosen by the surgeons based on the requirements of the case. Five orbital reconstructions were performed with this technique: 3 tumor reconstructions and 2 orbital fractures. Four of the 5 cases were secondary reconstructions. Molded Medpor Titan (Stryker, Kalamazoo, MI) implants were used in 4 cases and titanium mesh in 1 case. The stenciled and molded implants were adjusted no more than 2 times before anchored in place (mean 1). No case underwent further revision. The technique and cases presented demonstrate 1) the feasibility and accessibility of low-cost, independent use of 3D printing technology to fashion patient-specific implants in orbital reconstructions, 2) the ability to apply this technology to the surgeon's preference of any routinely implantable material, and 3) the utility of this technique in complex, secondary reconstructions.

Parallel R-matrix computation

International Nuclear Information System (INIS)

Heggarty, J.W.

1999-06-01

response to the challenge of achieving parallel R-matrix computation. The primary objective was to develop parallel codes, targeted at multicomputers, that are capable of performing R-matrix calculations hitherto intractable using classic supercomputers. In particular, Fortran implementations of two internal region methods (the R-matrix Floquet method and the two-dimensional R-matrix propagation method) and three external region methods (the Light-Walker propagation method, the Baluja, Burke and Morgan propagation method and the Variable Phase Method) from four widely utilised R-matrix packages were investigated to ascertain whether, in these cases, parallel R-matrix computation was practicable and, if so, to determine the most effective way to port such codes to contemporary multicomputers. When attempting to develop the parallel codes, a number of computer aided automatic parallelization tools were investigated. These were found to be inadequate. Consequently, a parallelization approach was developed to provide simple guidelines for manual parallelization. This parallelization approach proved effective and efficient parallel versions of the five R-matrix codes were successfully developed. (author)

Stable low-altitude orbits around Ganymede considering a disturbing body in a circular orbit

Science.gov (United States)

Cardoso dos Santos, J.; Carvalho, J. P. S.; Vilhena de Moraes, R.

2014-10-01

Some missions are being planned to visit Ganymede like the Europa Jupiter System Mission that is a cooperation between NASA and ESA to insert the spacecraft JGO (Jupiter Ganymede Orbiter) into Ganymedes orbit. This comprehension of the dynamics of these orbits around this planetary satellite is essential for the success of this type of mission. Thus, this work aims to perform a search for low-altitude orbits around Ganymede. An emphasis is given in polar orbits and it can be useful in the planning of space missions to be conducted around, with respect to the stability of orbits of artificial satellites. The study considers orbits of artificial satellites around Ganymede under the influence of the third-body (Jupiter's gravitational attraction) and the polygenic perturbations like those due to non-uniform distribution of mass (J_2 and J_3) of the main body. A simplified dynamic model for these perturbations is used. The Lagrange planetary equations are used to describe the orbital motion of the artificial satellite. The equations of motion are developed in closed form to avoid expansions in eccentricity and inclination. The results show the argument of pericenter circulating. However, low-altitude (100 and 150 km) polar orbits are stable. Another orbital elements behaved variating with small amplitudes. Thus, such orbits are convenient to be applied to future space missions to Ganymede. Acknowledgments: FAPESP (processes n° 2011/05671-5, 2012/12539-9 and 2012/21023-6).

Titan Orbiter Aerorover Mission

Science.gov (United States)

Sittler Jr., E. C.; Acuna, M.; Burchell, M. J.; Coates, A.; Farrell, W.; Flasar, M.; Goldstein, B. E.; Gorevan, S.; Hartle, R. E.; Johnson, W. T. K.

2001-01-01

We propose a combined Titan orbiter and Titan Aerorover mission with an emphasis on both in situ and remote sensing measurements of Titan's surface, atmosphere, ionosphere, and magnetospheric interaction. The biological aspect of the Titan environment will be emphasized by the mission (i.e., search for organic materials which may include simple organics to 'amono' analogues of amino acids and possibly more complex, lightening detection and infrared, ultraviolet, and charged particle interactions with Titan's surface and atmosphere). An international mission is assumed to control costs. NASA will provide the orbiter, launch vehicle, DSN coverage and operations, while international partners will provide the Aerorover and up to 30% of the cost for the scientific instruments through collaborative efforts. To further reduce costs we propose a single PI for orbiter science instruments and a single PI for Aerorover science instruments. This approach will provide single command/data and power interface between spacecraft and orbiter instruments that will have redundant central DPU and power converter for their instruments. A similar approach could be used for the Aerorover. The mission profile will be constructed to minimize conflicts between Aerorover science, orbiter radar science, orbiter radio science, orbiter imaging science, and orbiter fields and particles (FP) science. Additional information is contained in the original extended abstract.

Harmonically excited orbital variations

International Nuclear Information System (INIS)

Morgan, T.

1985-01-01

Rephrasing the equations of motion for orbital maneuvers in terms of Lagrangian generalized coordinates instead of Newtonian rectangular cartesian coordinates can make certain harmonic terms in the orbital angular momentum vector more readily apparent. In this formulation the equations of motion adopt the form of a damped harmonic oscillator when torques are applied to the orbit in a variationally prescribed manner. The frequencies of the oscillator equation are in some ways unexpected but can nonetheless be exploited through resonant forcing functions to achieve large secular variations in the orbital elements. Two cases are discussed using a circular orbit as the control case: (1) large changes in orbital inclination achieved by harmonic excitation rather than one impulsive velocity change, and (2) periodic and secular changes to the longitude of the ascending node using both stable and unstable excitation strategies. The implications of these equations are also discussed for both artificial satellites and natural satellites. For the former, two utilitarian orbits are suggested, each exploiting a form of harmonic excitation. 5 refs

Dynamic and reduced-dynamic precise orbit determination of satellites in low earth orbits

International Nuclear Information System (INIS)

Swatschina, P.

2009-01-01

The precise positioning of satellites in Low Earth Orbits (LEO) has become a key technology for advanced space missions. Dedicated satellite missions, such as CHAMP, GRACE and GOCE, that aim to map the Earths gravity field and its variation over time with unprecedented accuracy, initiated the demand for highly precise orbit solutions of LEO satellites. Furthermore, a wide range of additional science opportunities opens up with the capability to generate accurate LEO orbits. For all considered satellite missions, the primary measurement system for navigation is a spaceborne GPS receiver. The goal of this thesis is to establish and implement methods for Precise Orbit Determination (POD) of LEO satellites using GPS. Striving for highest precision using yet efficient orbit generation strategies, the attained orbit solutions are aimed to be competitive with the most advanced solutions of other institutions. Dynamic and reduced-dynamic orbit models provide the basic concepts of this work. These orbit models are subsequently adjusted to the highly accurate GPS measurements. The GPS measurements are introduced at the zero difference level in the ionosphere free linear combination. Appropriate procedures for GPS data screening and editing are established to detect erroneous data and to employ measurements of good quality only. For the dynamic orbit model a sophisticated force model, especially designed for LEO satellites, has been developed. In order to overcome the limitations that are induced by the deficiencies of the purely dynamical model, two different types of empirical parameters are introduced into the force model. These reduced-dynamic orbit models allow for the generation of much longer orbital arcs while preserving the spacecraft dynamics to the most possible extent. The two methods for reduced-dynamic orbit modeling are instantaneous velocity changes (pulses) or piecewise constant accelerations. For both techniques highly efficient modeling algorithms are

Advances in biomimetic regeneration of elastic matrix structures

Science.gov (United States)

Sivaraman, Balakrishnan; Bashur, Chris A.

2012-01-01

Elastin is a vital component of the extracellular matrix, providing soft connective tissues with the property of elastic recoil following deformation and regulating the cellular response via biomechanical transduction to maintain tissue homeostasis. The limited ability of most adult cells to synthesize elastin precursors and assemble them into mature crosslinked structures has hindered the development of functional tissue-engineered constructs that exhibit the structure and biomechanics of normal native elastic tissues in the body. In diseased tissues, the chronic overexpression of proteolytic enzymes can cause significant matrix degradation, to further limit the accumulation and quality (e.g., fiber formation) of newly deposited elastic matrix. This review provides an overview of the role and importance of elastin and elastic matrix in soft tissues, the challenges to elastic matrix generation in vitro and to regenerative elastic matrix repair in vivo, current biomolecular strategies to enhance elastin deposition and matrix assembly, and the need to concurrently inhibit proteolytic matrix disruption for improving the quantity and quality of elastogenesis. The review further presents biomaterial-based options using scaffolds and nanocarriers for spatio-temporal control over the presentation and release of these biomolecules, to enable biomimetic assembly of clinically relevant native elastic matrix-like superstructures. Finally, this review provides an overview of recent advances and prospects for the application of these strategies to regenerating tissue-type specific elastic matrix structures and superstructures. PMID:23355960

Thermoluminescence of meteorites and their orbits

Science.gov (United States)

Melcher, C. L.

1981-01-01

The thermoluminescence levels of 45 ordinary chondrites are measured in order to provide information on the orbital characteristics of the meteorites before impact. Glow curves of the photon emission response of powdered samples of the meteorites to temperatures up to 550 C in the natural state and following irradiation by a laboratory test dose of 110,000 rad were obtained as functions of terrestrial age and compared to those of samples of the Pribram, Lost City and Innisfree meteorites, for which accurate orbital data is available. The thermoluminescence levels in 40 out of 42 meteorites are found to be similar to those of the three control samples, indicating that the vast majority of ordinary chondrites that survive atmospheric entry have perihelia in the range 0.8-1 AU. Of the remaining two, Farmville is observed to exhibit an unusually large gradient in thermoluminescence levels with sample depth, which may be a result of a temperature gradient arising in a slowly rotating meteorite. Finally, the thermoluminescence measured in the Malakal meteorite is found to be two orders of magnitude lower than control samples, which is best explained by thermal draining by solar heating in an orbit with a perihelion distance of 0.5 to 0.6 AU.

Spin-orbit torques from interfacial spin-orbit coupling for various interfaces

Science.gov (United States)

Kim, Kyoung-Whan; Lee, Kyung-Jin; Sinova, Jairo; Lee, Hyun-Woo; Stiles, M. D.

2017-09-01

We use a perturbative approach to study the effects of interfacial spin-orbit coupling in magnetic multilayers by treating the two-dimensional Rashba model in a fully three-dimensional description of electron transport near an interface. This formalism provides a compact analytic expression for current-induced spin-orbit torques in terms of unperturbed scattering coefficients, allowing computation of spin-orbit torques for various contexts, by simply substituting scattering coefficients into the formulas. It applies to calculations of spin-orbit torques for magnetic bilayers with bulk magnetism, those with interface magnetism, a normal-metal/ferromagnetic insulator junction, and a topological insulator/ferromagnet junction. It predicts a dampinglike component of spin-orbit torque that is distinct from any intrinsic contribution or those that arise from particular spin relaxation mechanisms. We discuss the effects of proximity-induced magnetism and insertion of an additional layer and provide formulas for in-plane current, which is induced by a perpendicular bias, anisotropic magnetoresistance, and spin memory loss in the same formalism.

Orbit-attitude coupled motion around small bodies: Sun-synchronous orbits with Sun-tracking attitude motion

Science.gov (United States)

Kikuchi, Shota; Howell, Kathleen C.; Tsuda, Yuichi; Kawaguchi, Jun'ichiro

2017-11-01

The motion of a spacecraft in proximity to a small body is significantly perturbed due to its irregular gravity field and solar radiation pressure. In such a strongly perturbed environment, the coupling effect of the orbital and attitude motions exerts a large influence that cannot be neglected. However, natural orbit-attitude coupled dynamics around small bodies that are stationary in both orbital and attitude motions have yet to be observed. The present study therefore investigates natural coupled motion that involves both a Sun-synchronous orbit and Sun-tracking attitude motion. This orbit-attitude coupled motion enables a spacecraft to maintain its orbital geometry and attitude state with respect to the Sun without requiring active control. Therefore, the proposed method can reduce the use of an orbit and attitude control system. This paper first presents analytical conditions to achieve Sun-synchronous orbits and Sun-tracking attitude motion. These analytical solutions are then numerically propagated based on non-linear coupled orbit-attitude equations of motion. Consequently, the possibility of implementing Sun-synchronous orbits with Sun-tracking attitude motion is demonstrated.

Transfer matrix treatment of atomic chemisorption on transition metal surface

International Nuclear Information System (INIS)

Mariz, A.M.; Koiller, B.

1980-05-01

The atomic adsorption of hydrogen on paramagnetic nickel 100 surface is studied, using the Green's function formalism and the transfer matrix technique, which allows the treatment of the geometry of the system in a simple manner. Electronic correlation at the adatom orbital in a self consistent Hartree-Fock approach is incorporated. The adsorption energy, local density of states and charge transfer between the solid and the adatom are calculated for different crystal structures (sc and fcc) and adatom positions at the surface. The results are discussed in comparison with other theories and with available experimental data, with satisfactory agreement. (Author) [pt

Orbital Forcing driving climate variability on Tropical South Atlantic

Science.gov (United States)

Oliveira, A. S.; Baker, P. A.; Silva, C. G.; Dwyer, G. S.; Chiessi, C. M.; Rigsby, C. A.; Ferreira, F.

2017-12-01

Past research on climate response to orbital forcing in tropical South America has emphasized on high precession cycles influencing low latitude hydrologic cycles, and driving the meridional migration of Intertropical Convergence Zone (ITCZ).However, marine proxy records from the tropical Pacific Ocean showed a strong 41-ka periodicities in Pleistocene seawater temperature and productivity related to fluctuations in Earth's obliquity. It Indicates that the western Pacific ITCZ migration was influenced by combined precession and obliquity changes. To reconstruct different climate regimes over the continent and understand the orbital cycle forcing over Tropical South America climate, hydrological reconstruction have been undertaken on sediment cores located on the Brazilian continental slope, representing the past 1.6 million years. Core CDH 79 site is located on a 2345 m deep seamount on the northern Brazilian continental slope (00° 39.6853' N, 44° 20.7723' W), 320 km from modern coastline of the Maranhão Gulf. High-resolution XRF analyses of Fe, Ti, K and Ca are used to define the changes in precipitation and sedimentary input history of Tropical South America. The response of the hydrology cycle to orbital forcing was studied using spectral analysis.The 1600 ka records of dry/wet conditions presented here indicates that orbital time-scale climate change has been a dominant feature of tropical climate. We conclude that the observed oscillation reflects variability in the ITCZ activity associated with the Earth's tilt. The prevalence of the eccentricity and obliquity signals in continental hydrology proxies (Ti/Ca and Fe/K) as implicated in our precipitation records, highlights that these orbital forcings play an important role in tropics hydrologic cycles. Throughout the Quaternary abrupt shifts of tropical variability are temporally correlated with abrupt climate changes and atmospheric reorganization during Mid-Pleistocene Transition and Mid-Brunhes Events

The effect of chronic periodontitis on serum levels of matrix ...

African Journals Online (AJOL)

A complex network of chemokines and pro- and anti-inflammatory mediators is involved in the initiation and progression of chronic periodontitis. Matrix metalloproteinases (MMPs), the main enzymes responsible for matrix degradation, are important for periodontal tissue destruction, but their activity can be inhibited by tissue ...

Congenital orbital teratoma

OpenAIRE

Aiyub, Shereen; Chan, Weng Onn; Szetu, John; Sullivan, Laurence J; Pater, John; Cooper, Peter; Selva, Dinesh

2013-01-01

We present a case of mature congenital orbital teratoma managed with lid-sparing exenteration and dermis fat graft. This is a case report on the management of congenital orbital teratoma. A full-term baby was born in Fiji with prolapsed right globe which was surrounded by a nonpulsatile, cystic mass. Clinical and imaging features were consistent with congenital orbital teratoma. Due to limited surgical expertise, the patient was transferred to Adelaide, Australia for further management. The p...

Matrix precipitation: a general strategy to eliminate matrix interference for pharmaceutical toxic impurities analysis.

Science.gov (United States)

Yang, Xiaojing; Xiong, Xuewu; Cao, Ji; Luan, Baolei; Liu, Yongjun; Liu, Guozhu; Zhang, Lei

2015-01-30

Matrix interference, which can lead to false positive/negative results, contamination of injector or separation column, incompatibility between sample solution and the selected analytical instrument, and response inhibition or even quenching, is commonly suffered for the analysis of trace level toxic impurities in drug substance. In this study, a simple matrix precipitation strategy is proposed to eliminate or minimize the above stated matrix interference problems. Generally, a sample of active pharmaceutical ingredients (APIs) is dissolved in an appropriate solvent to achieve the desired high concentration and then an anti-solvent is added to precipitate the matrix substance. As a result, the target analyte is extracted into the mixed solution with very less residual of APIs. This strategy has the characteristics of simple manipulation, high recovery and excellent anti-interference capability. It was found that the precipitation ratio (R, representing the ability to remove matrix substance) and the proportion of solvent (the one used to dissolve APIs) in final solution (P, affecting R and also affecting the method sensitivity) are two important factors of the precipitation process. The correlation between R and P was investigated by performing precipitation with various APIs in different solvent/anti-solvent systems. After a detailed mathematical reasoning process, P=20% was proved to be an effective and robust condition to perform the precipitation strategy. The precipitation method with P=20% can be used as a general strategy for toxic impurity analysis in APIs. Finally, several typical examples are described in this article, where the challenging matrix interference issues have been resolved successfully. Copyright © 2014 Elsevier B.V. All rights reserved.

Investigation of Effects of Material Architecture on the Elastic Response of a Woven Ceramic Matrix Composite

Science.gov (United States)

Goldberg, Robert K.; Bonacuse, Peter J.; Mital, Subodh K.

2012-01-01

To develop methods for quantifying the effects of the microstructural variations of woven ceramic matrix composites on the effective properties and response of the material, a research program has been undertaken which is described in this paper. In order to characterize and quantify the variations in the microstructure of a five harness satin weave, CVI SiC/SiC, composite material, specimens were serially sectioned and polished to capture images that detailed the fiber tows, matrix, and porosity. Open source quantitative image analysis tools were then used to isolate the constituents and collect relevant statistics such as within ply tow spacing. This information was then used to build two dimensional finite element models that approximated the observed section geometry. With the aid of geometrical models generated by the microstructural characterization process, finite element models were generated and analyses were performed to quantify the effects of the microstructure and its variation on the effective stiffness and areas of stress concentration of the material. The results indicated that the geometry and distribution of the porosity appear to have significant effects on the through-thickness modulus. Similarly, stress concentrations on the outer surface of the composite appear to correlate to regions where the transverse tows are separated by a critical amount.

Many-body theory of electrical, thermal and optical response of molecular heterojunctions

Science.gov (United States)

Bergfield, Justin Phillip

In this work, we develop a many-body theory of electronic transport through single molecule junctions based on nonequilibrium Green's functions (NEGFs). The central quantity of this theory is the Coulomb self-energy matrix of the junction SigmaC. SigmaC is evaluated exactly in the sequential-tunneling limit, and the correction due to finite lead-molecule tunneling is evaluated using a conserving approximation based on diagrammatic perturbation theory on the Keldysh contour. In this way, tunneling processes are included to infinite order, meaning that any approximation utilized is a truncation in the physical processes considered rather than in the order of those processes. Our theory reproduces the key features of both the Coulomb blockade and coherent transport regimes simultaneously in a single unified theory. Nonperturbative effects of intramolecular correlations are included, which are necessary to accurately describe the highest occupied molecular orbital (HOMO)-lowest unoccupied molecular orbital (LUMO) gap, essential for a quantitative theory of transport. This work covers four major topics related to transport in single-molecule junctions. First, we use our many-body theory to calculate the nonlinear electrical response of the archetypal Au-1,4-benzenedithiol-Au junction and find irregularly shaped 'molecular diamonds' which have been experimentally observed in some larger molecules but which are inaccessible to existing theoretical approaches. Next, we extend our theory to include heat transport and develop an exact expression for the heat current in an interacting nanostructure. Using this result, we discover that quantum coherence can strongly enhance the thermoelectric response of a device, a result with a number of technological applications. We then develop the formalism to include multi-orbital lead-molecule contacts and multi-channel leads, both of which strongly affect the observable transport. Lastly, we include a dynamic screening correction to

Cu 4s → 4p atomic like excitations in the Ne matrix.

Science.gov (United States)

Hatano, Yasuyo; Tatewaki, Hiroshi; Yamamoto, Shigeyoshi

2013-06-07

The lowest three or four excited states (the triplet or quartet states) of the Cu atom in a neon (Ne) matrix have been studied experimentally, and have been presumed to have the electronic configuration of Cu 4p(1). The origins of the triplet and the quartet are not yet fully clear, although many models have been proposed. It has been argued, for example, that the existence of different trapping sites would give rise to two partly overlapping triplets, leading to spectra having three or four lines or more. Below, the electronic structures of the ground state and lowest excited states of the Cu atom in the neon matrix are clarified by means of ab initio molecular orbital calculations, using the cluster model. It was found that a rather large vacancy (hollow) with residual Ne atoms is vital for explaining the observed spectra having three or more lines; the Cu atom occupies the center of the substitutional site of a face-centered cubic (fcc)-like cluster comprising 66 Ne atoms, in which the first shell composed of 12 Ne atoms is empty. The presence of the residual Ne atoms in the first shell gives rise to more than three excited states, explaining the experimental spectra. Electron-electron interaction (including the crystal field) and spin-orbit interaction are both important in explaining the experimental spectra.

Effect of the sample matrix on measurement uncertainty in X-ray fluorescence analysis

International Nuclear Information System (INIS)

Morgenstern, P.; Brueggemann, L.; Wennrich, R.

2005-01-01

The estimation of measurement uncertainty, with reference to univariate calibration functions, is discussed in detail in the Eurachem Guide 'Quantifying Uncertainty in Analytical Measurement'. The adoption of these recommendations to quantitative X-ray fluorescence analysis (XRF) involves basic problems which are above all due to the strong influence of the sample matrix on the analytical response. In XRF-analysis, the proposed recommendations are consequently applicable only to the matrix corrected response. The application is also restricted with regard to both the matrices and analyte concentrations. In this context the present studies are aimed at the problems to predict measurement uncertainty also with reference to more variable sample compositions. The corresponding investigations are focused on the use of the intensity of the Compton scattered tube line as an internal standard to assess the effect of the individual sample matrix on the analytical response relatively to a reference matrix. Based on this concept the estimation of the measurement uncertainty of an analyte presented in an unknown specimen can be predicted in consideration of the data obtained under defined matrix conditions

A SIMPLE AND RAPID MATRIX-ASSISTED LASER DESORPTION/IONIZATION TIME OF FLIGHT MASS SPECTROMETRY METHOD TO SCREEN FISH PLASMA SAMPLES FOR ESTROGEN-RESPONSIVE BIOMARKERS

Science.gov (United States)

In this study, we describe and evaluate the performance of a simple and rapid mass spectral method for screening fish plasma for estrogen-responsive biomarkers using matrix assisted laster desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS) couopled with a short...

Topology of tokamak orbits

International Nuclear Information System (INIS)

Rome, J.A.; Peng, Y.K.M.

1978-09-01

Guiding center orbits in noncircular axisymmetric tokamak plasmas are studied in the constants of motion (COM) space of (v, zeta, psi/sub m/). Here, v is the particle speed, zeta is the pitch angle with respect to the parallel equilibrium current, J/sub parallels/, and psi/sub m/ is the maximum value of the poloidal flux function (increasing from the magnetic axis) along the guiding center orbit. Two D-shaped equilibria in a flux-conserving tokamak having β's of 1.3% and 7.7% are used as examples. In this space, each confined orbit corresponds to one and only one point and different types of orbits (e.g., circulating, trapped, stagnation and pinch orbits) are represented by separate regions or surfaces in the space. It is also shown that the existence of an absolute minimum B in the higher β (7.7%) equilibrium results in a dramatically different orbit topology from that of the lower β case. The differences indicate the confinement of additional high energy (v → c, within the guiding center approximation) trapped, co- and countercirculating particles whose orbit psi/sub m/ falls within the absolute B well

Feasibility of a responsive, hybrid propulsion augmented, Vertical-Takeoff-and-Landing, Single-Stage-to-Orbit launch system

Science.gov (United States)

Pelaccio, Dennis G.

1996-03-01

A novel, reusable, Vertical-Takeoff-and-Landing, Single-Stage-to-Orbit (VTOL/SSTO) launch system concept, named HYP-SSTO, is presented in this paper. This launch vehicle system concept uses a highly coupled, main high performance liquid oxygen/liquid hydrogen (LOX/LH2) propulsion system, that is used only for launch, with a hybrid auxiliary propulsion system which is used during final orbit insertion, major orbit maneuvering, and landing propulsive burn phases of flight. By using a hybrid propulsion system for major orbit maneuver burns and landing, this launch system concept has many advantages over conventional VTOL/SSTO concepts that use LOX/LH2 propulsion system(s) burns for all phases of flight. Because hybrid propulsion systems are relatively simple and inert by their nature, this concept has the potential to support short turnaround times between launches, be economical to develop, and be competitive in terms of overall system life-cycle cost. This paper provides a technical description of the novel, reusable HYP-SSTO launch system concept. Launch capability performance, as well as major design and operational system attributes, are identified and discussed.

Orbital Radiotherapy Combined With Corticosteroid Treatment for Thyroid Eye Disease-Compressive Optic Neuropathy.

Science.gov (United States)

Gold, Katherine G; Scofield, Stacy; Isaacson, Steven R; Stewart, Michael W; Kazim, Michael

To evaluate the effectiveness of orbital radiotherapy (ORT) in the treatment of thyroid eye disease (TED)-compressive optic neuropathy. A retrospective review of patients with corticosteroid-responsive compressive optic neuropathy due to TED treated with ORT. Study was conducted in compliance with Health Insurance Portability and Accountability Act. One hundred four patients (163 orbits) with a mean age of 61.7 years met inclusion criteria. Seventy-four percent (77/104) were female, and 32.7% (34/104) were current or previous smokers. A total absorbed dose of 2000 cGy fractionated in 10 treatment doses over the course of 2 weeks was administered to the retroocular tissues according to a standard protocol. The primary end point was failure of ORT, defined as persistent optic neuropathy following completion of radiotherapy that mandated urgent orbital decompression surgery. Ninety-eight of 104 (94%) patients or 152 of 163 (93.3%) orbits did not require orbital decompression surgery during the acute phase. Patients who responded successfully to ORT had similar improvements in visual acuity, color vision, Humphrey threshold visual field testing, and afferent pupillary defects compared with patients who failed ORT and underwent urgent decompression surgery. Only 36.7% of successfully treated patients ultimately underwent elective surgery, including orbital decompression, strabismus, or eyelid surgery, during the inactive phase of TED. The data from this study, the largest retrospective review reported to date, supports the use of ORT in eyes with corticosteroid-responsive TED-compressive optic neuropathy. ORT may favorably alter the natural history of active-phase TED by preventing recurrent compressive optic neuropathy after withdrawal of corticosteroids.

The effects of orbital spaceflight on bone histomorphometry and messenger ribonucleic acid levels for bone matrix proteins and skeletal signaling peptides in ovariectomized growing rats

Science.gov (United States)

Cavolina, J. M.; Evans, G. L.; Harris, S. A.; Zhang, M.; Westerlind, K. C.; Turner, R. T.

1997-01-01

A 14-day orbital spaceflight was performed using ovariectomized Fisher 344 rats to determine the combined effects of estrogen deficiency and near weightlessness on tibia radial bone growth and cancellous bone turnover. Twelve ovariectomized rats with established cancellous osteopenia were flown aboard the space shuttle Columbia (STS-62). Thirty ovariectomized rats were housed on earth as ground controls: 12 in animal enclosure modules, 12 in vivarium cages, and 6 killed the day of launch for baseline measurements. An additional 18 ovary-intact rats were housed in vivarium cages as ground controls: 8 rats were killed as baseline controls and the remaining 10 rats were killed 14 days later. Ovariectomy increased periosteal bone formation at the tibia-fibula synostosis; cancellous bone resorption and formation in the secondary spongiosa of the proximal tibial metaphysis; and messenger RNA (mRNA) levels for the prepro-alpha2(1) subunit of type 1 collagen, osteocalcin, transforming growth factor-beta, and insulin-like growth factor I in the contralateral proximal tibial metaphysis and for the collagen subunit in periosteum pooled from tibiae and femora and decreased cancellous bone area. Compared to ovariectomized weight-bearing rats, the flight group experienced decreases in periosteal bone formation, collagen subunit mRNA levels, and cancellous bone area. The flight rats had a small decrease in the cancellous mineral apposition rate, but no change in the calculated bone formation rate. Also, spaceflight had no effect on cancellous osteoblast and osteoclast perimeters or on mRNA levels for bone matrix proteins and signaling peptides. On the other hand, spaceflight resulted in an increase in bone resorption, as ascertained from the diminished retention of a preflight fluorochrome label. This latter finding suggests that osteoclast activity was increased. In a follow-up ground-based experiment, unilateral sciatic neurotomy of ovariectomized rats resulted in cancellous

Correlation between the 2-Dimensional Extent of Orbital Defects and the 3-Dimensional Volume of Herniated Orbital Content in Patients with Isolated Orbital Wall Fractures

Directory of Open Access Journals (Sweden)

Jong Hyun Cha

2017-01-01

Full Text Available BackgroundThe purpose of this study was to assess the correlation between the 2-dimensional (2D extent of orbital defects and the 3-dimensional (3D volume of herniated orbital content in patients with an orbital wall fracture.MethodsThis retrospective study was based on the medical records and radiologic data of 60 patients from January 2014 to June 2016 for a unilateral isolated orbital wall fracture. They were classified into 2 groups depending on whether the fracture involved the inferior wall (group I, n=30 or the medial wall (group M, n=30. The 2D area of the orbital defect was calculated using the conventional formula. The 2D extent of the orbital defect and the 3D volume of herniated orbital content were measured with 3D image processing software. Statistical analysis was performed to evaluate the correlations between the 2D and 3D parameters.ResultsVarying degrees of positive correlation were found between the 2D extent of the orbital defects and the 3D herniated orbital volume in both groups (Pearson correlation coefficient, 0.568−0.788; R2=32.2%−62.1%.ConclusionsBoth the calculated and measured 2D extent of the orbital defects showed a positive correlation with the 3D herniated orbital volume in orbital wall fractures. However, a relatively large volume of herniation (>0.9 cm3 occurred not infrequently despite the presence of a small orbital defect (<1.9 cm2. Therefore, estimating the 3D volume of the herniated content in addition to the 2D orbital defect would be helpful for determining whether surgery is indicated and ensuring adequate surgical outcomes.

An optimum organizational structure for a large earth-orbiting multidisciplinary Space Base

Science.gov (United States)

Ragusa, J. M.

1973-01-01

The purpose of this exploratory study was to identify an optimum hypothetical organizational structure for a large earth-orbiting multidisciplinary research and applications (R&A) Space Base manned by a mixed crew of technologists. Since such a facility does not presently exist, in situ empirical testing was not possible. Study activity was, therefore, concerned with the identification of a desired organizational structural model rather than the empirical testing of it. The essential finding of this research was that a four-level project type 'total matrix' model will optimize the efficiency and effectiveness of Space Base technologists.

Neonatal orbital abscess

Directory of Open Access Journals (Sweden)

Khalil M Al-Salem

2014-01-01

Full Text Available Orbital complications due to ethmoiditis are rare in neonates. A case of orbital abscess due to acute ethmoiditis in a 28-day-old girl is presented. A Successful outcome was achieved following antimicrobial therapy alone; spontaneous drainage of the abscess occurred from the lower lid without the need for surgery. From this case report, we intend to emphasize on eyelid retraction as a sign of neonatal orbital abscess, and to review all the available literature of similar cases.

The on-orbit calibration of the Fermi Large Area Telescope

Energy Technology Data Exchange (ETDEWEB)

Ackermann, M.; Ajello, M.; Bartelt, J.; Bechtol, K.; Berenji, B.; Bloom, E.D.; Bogart, J.R.; Borgland, A.W.; Bouvier, A.; Cameron, R.A.; Campell, M.; Charles, E.; Chiang, J.; Claus, R.; Condamoor, S.; Digel, S.W.; Silva, E.D.E.; Drell, P.S.; Dubois, R.; Edmonds, Y.; Flath, D.L.; Focke, W.B.; Fouts, K.; Freytag, D.; Funk, S.; Glanzman, T.; Godfrey, G.; Goodman, J.; Hakimi, M.; Haller, G.; Hart, P.A.; Huffer, M.; Johannesson, G.; Johnson, A.S.; Kamae, T.; Kavelaars, A.; Kelly, H.; Kocian, M.L.; Lee, S.H.; Madejski, G.M.; Michelson, P.F.; Mitra, P.; Mitthumsiri, W.; Monzani, M.E.; Moskalenko, I.V.; Murgia, S.; Nelson, D.; Nolan, P.L.; Paneque, D.; Panetta, J.H.; Rochester, L.S.; Romani, R.W.; Sapozhnikov, L.; Saxton, O.H.; Sugizaki, M.; Tajima, H.; Tanaka, T.; Thayer, J.B.; Thayer, J.G.; Tramacere, A.; Turri, M.; Usher, T.L.; Wai, L.L.; Waite, A.P.; Wang, P. [Stanford Univ, WW Hansen Expt Phys Lab, Kavli Inst Particle Astrophys and Cosmol, Dept Phys, Stanford, CA 94305 (United States); Ackermann, M.; Ajello, M.; Bartelt, J.; Bechtol, K.; Berenji, B.; Bloom, E.D.; Bogart, J.R.; Borgland, A.W.; Bouvier, A.; Cameron, R.A.; Campell, M.; Charles, E.; Chiang, J.; Claus, R.; Condamoor, S.; Digel, S.W.; Silva, E.D.E.; Drell, P.S.; Dubois, R.; Edmonds, Y.; Flath, D.L.; Focke, W.B.; Fouts, K.; Freytag, D.; Funk, S.; Glanzman, T.; Godfrey, G.; Goodman, J.; Hakimi, M.; Haller, G.; Hart, P.A.; Huffer, M.; Johannesson, G.; Johnson, A.S.; Kamae, T.; Kavelaars, A.; Kelly, H.; Kocian, M.L.; Lee, S.H.; Madejski, G.M.; Michelson, P.F.; Mitra, P.; Mitthumsiri, W.; Monzani, M.E.; Moskalenko, I.V.; Murgia, S.; Nelson, D.; Nolan, P.L.; Paneque, D.; Panetta, J.H.; Rochester, L.S.; Romani, R.W.; Sapozhnikov, L.; Saxton, O.H.; Sugizaki, M.; Tajima, H.; Tanaka, T.; Thayer, J.B; Thayer, J.G.; Tramacere, A.; Turri, M.; Usher, T.L.; Wai, L.L.; Waite, A.P.; Wang, P. [Stanford Univ, SLAC Natl Accelerator Lab, Stanford, CA 94305 (United States)] [and others

2009-07-01

The Large Area Telescope (LAT) on-board the Fermi Gamma-ray Space Telescope began its on-orbit operations on June 23, 2008. Calibrations, defined in a generic sense, correspond to synchronization of trigger signals, optimization of delays for latching data, determination of detector thresholds, gains and responses, evaluation of the perimeter of the South Atlantic Anomaly (SAA), measurements of live time, of absolute time, and internal and spacecraft bore-sight alignments. Here we describe on-orbit calibration results obtained using known astrophysical sources, galactic cosmic rays, and charge injection into the front-end electronics of each detector. Instrument response functions will be described in a separate publication. This paper demonstrates the stability of calibrations and describes minor changes observed since launch. These results have been used to calibrate the LAT datasets to be publicly released in August 2009. (authors)

The on-orbit calibration of the Fermi Large Area Telescope

International Nuclear Information System (INIS)

Ackermann, M.; Ajello, M.; Bartelt, J.; Bechtol, K.; Berenji, B.; Bloom, E.D.; Bogart, J.R.; Borgland, A.W.; Bouvier, A.; Cameron, R.A.; Campell, M.; Charles, E.; Chiang, J.; Claus, R.; Condamoor, S.; Digel, S.W.; Silva, E.D.E.; Drell, P.S.; Dubois, R.; Edmonds, Y.; Flath, D.L.; Focke, W.B.; Fouts, K.; Freytag, D.; Funk, S.; Glanzman, T.; Godfrey, G.; Goodman, J.; Hakimi, M.; Haller, G.; Hart, P.A.; Huffer, M.; Johannesson, G.; Johnson, A.S.; Kamae, T.; Kavelaars, A.; Kelly, H.; Kocian, M.L.; Lee, S.H.; Madejski, G.M.; Michelson, P.F.; Mitra, P.; Mitthumsiri, W.; Monzani, M.E.; Moskalenko, I.V.; Murgia, S.; Nelson, D.; Nolan, P.L.; Paneque, D.; Panetta, J.H.; Rochester, L.S.; Romani, R.W.; Sapozhnikov, L.; Saxton, O.H.; Sugizaki, M.; Tajima, H.; Tanaka, T.; Thayer, J.B.; Thayer, J.G.; Tramacere, A.; Turri, M.; Usher, T.L.; Wai, L.L.; Waite, A.P.; Wang, P.; Ackermann, M.; Ajello, M.; Bartelt, J.; Bechtol, K.; Berenji, B.; Bloom, E.D.; Bogart, J.R.; Borgland, A.W.; Bouvier, A.; Cameron, R.A.; Campell, M.; Charles, E.; Chiang, J.; Claus, R.; Condamoor, S.; Digel, S.W.; Silva, E.D.E.; Drell, P.S.; Dubois, R.; Edmonds, Y.; Flath, D.L.; Focke, W.B.; Fouts, K.; Freytag, D.; Funk, S.; Glanzman, T.; Godfrey, G.; Goodman, J.; Hakimi, M.; Haller, G.; Hart, P.A.; Huffer, M.; Johannesson, G.; Johnson, A.S.; Kamae, T.; Kavelaars, A.; Kelly, H.; Kocian, M.L.; Lee, S.H.; Madejski, G.M.; Michelson, P.F.; Mitra, P.; Mitthumsiri, W.; Monzani, M.E.; Moskalenko, I.V.; Murgia, S.; Nelson, D.; Nolan, P.L.; Paneque, D.; Panetta, J.H.; Rochester, L.S.; Romani, R.W.; Sapozhnikov, L.; Saxton, O.H.; Sugizaki, M.; Tajima, H.; Tanaka, T.; Thayer, J.B; Thayer, J.G.; Tramacere, A.; Turri, M.; Usher, T.L.; Wai, L.L.; Waite, A.P.; Wang, P.; Abdo, A.A.; Ampe, J.; Chekhtman, A.; Dermer, C.D.; Fewtrell, Z.; Grove, J.E.; Johnson, W.N.; Leas, B.; Lovellette, M.N.; Makeev, A.; May, D.; Raynor, W.; Strickman, M.S.; Wood, D.L.; Wood, K.S.; Abdo, A.A.; Anderson, B.; Atwood, W.B.; Dormody, M.; Johnson, R.P.; Porter, T.A.; Sadrozinski, H.F.W.; Parkinson, P.M.S.; Ziegler, M.; Anderson, B.; Atwood, W.B.; Dormody, M.; Johnson, R.P.; Porter, T.A.; Sadrozinski, H.F.W.; Parkinson, P.M.S.; Ziegler, M.; Axelsson, M.; Axelsson, M.; Carlson, P.; Conrad, J.; Klamra, W.; McGlynn, S.; Meurer, C.; Ryde, F.; Sellerholm, A.; Ylinen, T.; Bagagli, R.; Baldini, L.; Bellardi, F.; Bellazzini, R.; Bregeon, J.; Brez, A.; Ceccanti, M.; Fabiani, D.; Kuss, M.; Latronico, L.; Massai, M.M.; Minuti, M.; Omodei, N.; Pesce-Rollins, M.; Pinchera, M.; Rapposelli, E.; Razzano, M.; Saggini, N.; Sgro, C.; Spandre, G.; Tenze, A.; Ballet, J.; Casandjian, J.M.; Grenier, I.A.; Starck, J.L.

2009-01-01

The Large Area Telescope (LAT) on-board the Fermi Gamma-ray Space Telescope began its on-orbit operations on June 23, 2008. Calibrations, defined in a generic sense, correspond to synchronization of trigger signals, optimization of delays for latching data, determination of detector thresholds, gains and responses, evaluation of the perimeter of the South Atlantic Anomaly (SAA), measurements of live time, of absolute time, and internal and spacecraft bore-sight alignments. Here we describe on-orbit calibration results obtained using known astrophysical sources, galactic cosmic rays, and charge injection into the front-end electronics of each detector. Instrument response functions will be described in a separate publication. This paper demonstrates the stability of calibrations and describes minor changes observed since launch. These results have been used to calibrate the LAT datasets to be publicly released in August 2009. (authors)

The On-Orbit Calibrations for the Fermi Large Area Telescope

Energy Technology Data Exchange (ETDEWEB)

Abdo, Aous A.; /Naval Research Lab, Wash., D.C.; Ackermann, M.; /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept.; Ajello, M.; /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept.; Ampe, J.; /Naval Research Lab, Wash., D.C.; Anderson, B.; /UC, Santa Cruz; Atwood, W.B.; /UC, Santa Cruz; Axelsson, M.; /Stockholm U., OKC /Stockholm U.; Bagagli, R.; /INFN, Pisa; Baldini, L.; /INFN, Pisa; Ballet, J.; /DAPNIA, Saclay; Barbiellini, Guido; /INFN, Trieste /Trieste U.; Bartelt, J.; /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept.; Bastieri, Denis; /INFN, Padua /Padua U.; Baughman, B.M.; /Ohio State U.; Bechtol, K.; /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept.; Bederede, D.; /DAPNIA, Saclay; Bellardi, F.; /INFN, Pisa; Bellazzini, R.; /INFN, Pisa; Belli, F.; /Frascati /Rome U.,Tor Vergata; Berenji, B.; /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept.; Bisello, D.; /INFN, Padua /Padua U. /Garching, Max Planck Inst., MPE /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept. /Ecole Polytechnique /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept. /INFN, Perugia /Perugia U. /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept. /DAPNIA, Saclay /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept. /INFN, Pisa /INFN, Pisa /Bari U. /INFN, Bari /Ecole Polytechnique /Washington U., Seattle /INFN, Padua /Padua U. /Bari U. /INFN, Bari /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept. /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept. /IASF, Milan /IASF, Milan /Kalmar U. /Stockholm U., OKC /Royal Inst. Tech., Stockholm /DAPNIA, Saclay /ASDC, Frascati /INFN, Pisa /INFN, Perugia /Perugia U. /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept. /George Mason U. /Naval Research Lab, Wash., D.C. /NASA, Goddard /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept. /DAPNIA, Saclay /NASA, Goddard /INFN, Perugia /Perugia U.; /more authors..

2011-11-17

The Large Area Telescope (LAT) on-board the Fermi Gamma-ray Space Telescope began its on-orbit operations on June 23, 2008. Calibrations, defined in a generic sense, correspond to synchronization of trigger signals, optimization of delays for latching data, determination of detector thresholds, gains and responses, evaluation of the perimeter of the South Atlantic Anomaly (SAA), measurements of live time, of absolute time, and internal and spacecraft boresight alignments. Here we describe on-orbit calibration results obtained using known astrophysical sources, galactic cosmic rays, and charge injection into the front-end electronics of each detector. Instrument response functions will be described in a separate publication. This paper demonstrates the stability of calibrations and describes minor changes observed since launch. These results have been used to calibrate the LAT datasets to be publicly released in August 2009.

Exchange-correlation energy from pairing matrix fluctuation and the particle-particle random phase approximation.

Science.gov (United States)

van Aggelen, Helen; Yang, Yang; Yang, Weitao

2014-05-14

Despite their unmatched success for many applications, commonly used local, semi-local, and hybrid density functionals still face challenges when it comes to describing long-range interactions, static correlation, and electron delocalization. Density functionals of both the occupied and virtual orbitals are able to address these problems. The particle-hole (ph-) Random Phase Approximation (RPA), a functional of occupied and virtual orbitals, has recently known a revival within the density functional theory community. Following up on an idea introduced in our recent communication [H. van Aggelen, Y. Yang, and W. Yang, Phys. Rev. A 88, 030501 (2013)], we formulate more general adiabatic connections for the correlation energy in terms of pairing matrix fluctuations described by the particle-particle (pp-) propagator. With numerical examples of the pp-RPA, the lowest-order approximation to the pp-propagator, we illustrate the potential of density functional approximations based on pairing matrix fluctuations. The pp-RPA is size-extensive, self-interaction free, fully anti-symmetric, describes the strong static correlation limit in H2, and eliminates delocalization errors in H2(+) and other single-bond systems. It gives surprisingly good non-bonded interaction energies--competitive with the ph-RPA--with the correct R(-6) asymptotic decay as a function of the separation R, which we argue is mainly attributable to its correct second-order energy term. While the pp-RPA tends to underestimate absolute correlation energies, it gives good relative energies: much better atomization energies than the ph-RPA, as it has no tendency to underbind, and reaction energies of similar quality. The adiabatic connection in terms of pairing matrix fluctuation paves the way for promising new density functional approximations.

Exchange-correlation energy from pairing matrix fluctuation and the particle-particle random phase approximation

International Nuclear Information System (INIS)

Aggelen, Helen van; Yang, Yang; Yang, Weitao

2014-01-01

Despite their unmatched success for many applications, commonly used local, semi-local, and hybrid density functionals still face challenges when it comes to describing long-range interactions, static correlation, and electron delocalization. Density functionals of both the occupied and virtual orbitals are able to address these problems. The particle-hole (ph-) Random Phase Approximation (RPA), a functional of occupied and virtual orbitals, has recently known a revival within the density functional theory community. Following up on an idea introduced in our recent communication [H. van Aggelen, Y. Yang, and W. Yang, Phys. Rev. A 88, 030501 (2013)], we formulate more general adiabatic connections for the correlation energy in terms of pairing matrix fluctuations described by the particle-particle (pp-) propagator. With numerical examples of the pp-RPA, the lowest-order approximation to the pp-propagator, we illustrate the potential of density functional approximations based on pairing matrix fluctuations. The pp-RPA is size-extensive, self-interaction free, fully anti-symmetric, describes the strong static correlation limit in H 2 , and eliminates delocalization errors in H 2 + and other single-bond systems. It gives surprisingly good non-bonded interaction energies – competitive with the ph-RPA – with the correct R −6 asymptotic decay as a function of the separation R, which we argue is mainly attributable to its correct second-order energy term. While the pp-RPA tends to underestimate absolute correlation energies, it gives good relative energies: much better atomization energies than the ph-RPA, as it has no tendency to underbind, and reaction energies of similar quality. The adiabatic connection in terms of pairing matrix fluctuation paves the way for promising new density functional approximations

Space Shuttle Orbiter logistics - Managing in a dynamic environment

Science.gov (United States)

Renfroe, Michael B.; Bradshaw, Kimberly

1990-01-01

The importance and methods of monitoring logistics vital signs, logistics data sources and acquisition, and converting data into useful management information are presented. With the launch and landing site for the Shuttle Orbiter project at the Kennedy Space Center now totally responsible for its own supportability posture, it is imperative that logistics resource requirements and management be continually monitored and reassessed. Detailed graphs and data concerning various aspects of logistics activities including objectives, inventory operating levels, customer environment, and data sources are provided. Finally, some lessons learned from the Shuttle Orbiter project and logistics options which should be considered by other space programs are discussed.

Maintaining Aura's Orbit Requirements While Performing Orbit Maintenance Maneuvers Containing an Orbit Normal Delta-V Component

Science.gov (United States)

Johnson, Megan R.; Petersen, Jeremy D.

2014-01-01

The Earth Observing System (EOS) Afternoon Constellation consists of five member missions (GCOM-W1, Aqua, CALIPSO, CloudSat, and Aura), each of which maintain a frozen, sun-synchronous orbit with a 16-day repeating ground track that follows the Worldwide Reference System-2 (WRS-2). Under nominal science operations for Aura, the propulsion system is oriented such that the resultant thrust vector is aligned 13.493 degrees away from the velocity vector along the yaw axis. When performing orbit maintenance maneuvers, the spacecraft performs a yaw slew to align the thrust vector in the appropriate direction. A new Drag Make Up (DMU) maneuver operations scheme has been implemented for Aura alleviating the need for the 13.493 degree yaw slew. The focus of this investigation is to assess the impact that no-slew DMU maneuver operations will have on Aura's Mean Local Time (MLT) which drives the required along track separation between Aura and the constellation members, as well as Aura's frozen orbit properties, eccentricity and argument of perigee. Seven maneuver strategies were analyzed to determine the best operational approach. A mirror pole strategy, with maneuvers alternating at the North and South poles, was implemented operationally to minimize impact to the MLT. Additional analysis determined that the mirror pole strategy could be further modified to include frozen orbit maneuvers and thus maintain both MLT and the frozen orbit properties under noslew operations.

Phenomenological renormalization of free nucleon-nucleon interaction. [Sussex matrix elements

Energy Technology Data Exchange (ETDEWEB)

Prakash, M; Waghmare, Y R [Indian Inst. of Tech., Kanpur. Dept. of Physics; Mehrotra, I [Allahabad Univ. (India). Dept. of Physics

1976-08-01

Low-lying spectra of /sup 6/Li, /sup 18/F, /sup 18/O, /sup 42/Sc, /sup 42/Ca, /sup 58/Ni and /sup 92/Zr are studied with Sussex matrix elements (SME) and their central, spin-orbit and tensor components. It is observed that major contribution to level energies comes from the central part, while the tensor part provides the finer details of spectra, particularly for T = 0 levels. The spin-orbit part does not make any appreciable contribution to level energies. A phenomenological renormalization fo the SME is carried out to improve the agreement with the experimental results. It turns out that some of the low-lying T = 0 levels can be satisfactorily described if the SME in the /sup 3/S/sub 1/ relative state are made (1+..cap alpha..) times their bare interaction value, where ..cap alpha.. is a constant to be determined from a comparison with experimental level energies. Similarly, for T = 1 levels, better agreement with the experimental results is obtained if a delta-function-plus-quadrupole interaction is added to the SME.

Computing the Density Matrix in Electronic Structure Theory on Graphics Processing Units.

Science.gov (United States)

Cawkwell, M J; Sanville, E J; Mniszewski, S M; Niklasson, Anders M N

2012-11-13

The self-consistent solution of a Schrödinger-like equation for the density matrix is a critical and computationally demanding step in quantum-based models of interatomic bonding. This step was tackled historically via the diagonalization of the Hamiltonian. We have investigated the performance and accuracy of the second-order spectral projection (SP2) algorithm for the computation of the density matrix via a recursive expansion of the Fermi operator in a series of generalized matrix-matrix multiplications. We demonstrate that owing to its simplicity, the SP2 algorithm [Niklasson, A. M. N. Phys. Rev. B2002, 66, 155115] is exceptionally well suited to implementation on graphics processing units (GPUs). The performance in double and single precision arithmetic of a hybrid GPU/central processing unit (CPU) and full GPU implementation of the SP2 algorithm exceed those of a CPU-only implementation of the SP2 algorithm and traditional matrix diagonalization when the dimensions of the matrices exceed about 2000 × 2000. Padding schemes for arrays allocated in the GPU memory that optimize the performance of the CUBLAS implementations of the level 3 BLAS DGEMM and SGEMM subroutines for generalized matrix-matrix multiplications are described in detail. The analysis of the relative performance of the hybrid CPU/GPU and full GPU implementations indicate that the transfer of arrays between the GPU and CPU constitutes only a small fraction of the total computation time. The errors measured in the self-consistent density matrices computed using the SP2 algorithm are generally smaller than those measured in matrices computed via diagonalization. Furthermore, the errors in the density matrices computed using the SP2 algorithm do not exhibit any dependence of system size, whereas the errors increase linearly with the number of orbitals when diagonalization is employed.

Update on orbital reconstruction.

Science.gov (United States)

Chen, Chien-Tzung; Chen, Yu-Ray

2010-08-01

Orbital trauma is common and frequently complicated by ocular injuries. The recent literature on orbital fracture is analyzed with emphasis on epidemiological data assessment, surgical timing, method of approach and reconstruction materials. Computed tomographic (CT) scan has become a routine evaluation tool for orbital trauma, and mobile CT can be applied intraoperatively if necessary. Concomitant serious ocular injury should be carefully evaluated preoperatively. Patients presenting with nonresolving oculocardiac reflex, 'white-eyed' blowout fracture, or diplopia with a positive forced duction test and CT evidence of orbital tissue entrapment require early surgical repair. Otherwise, enophthalmos can be corrected by late surgery with a similar outcome to early surgery. The use of an endoscope-assisted approach for orbital reconstruction continues to grow, offering an alternative method. Advances in alloplastic materials have improved surgical outcome and shortened operating time. In this review of modern orbital reconstruction, several controversial issues such as surgical indication, surgical timing, method of approach and choice of reconstruction material are discussed. Preoperative fine-cut CT image and thorough ophthalmologic examination are key elements to determine surgical indications. The choice of surgical approach and reconstruction materials much depends on the surgeon's experience and the reconstruction area. Prefabricated alloplastic implants together with image software and stereolithographic models are significant advances that help to more accurately reconstruct the traumatized orbit. The recent evolution of orbit reconstruction improves functional and aesthetic results and minimizes surgical complications.

A New Orbit for the Eclipsing Binary V577 Oph

Energy Technology Data Exchange (ETDEWEB)

Jeffery, Elizabeth J. [Physics Department, California Polytechnic State University, San Luis Obispo, CA 93407 (United States); Barnes, Thomas G. III; Montemayor, Thomas J. [The University of Texas at Austin, McDonald Observatory, 1 University Station, C1402, Austin, TX 78712-0259 (United States); Skillen, Ian, E-mail: ejjeffer@calpoly.edu, E-mail: tgb@astro.as.utexas.edu, E-mail: tm@astro.as.utexas.edu, E-mail: wji@ing.iac.es [Isaac Newton Group, Apartado de Correos 321, E-38700 Santa Cruz de La Palma, Canary Islands (Spain)

2017-09-01

Pulsating stars in eclipsing binary systems are unique objects for providing constraints on stellar models. To fully leverage the information available from the binary system, full orbital radial velocity curves must be obtained. We report 23 radial velocities for components of the eclipsing binary V577 Oph, whose primary star is a δ Sct variable. The velocities cover a nearly complete orbit and a time base of 20 years. We computed orbital elements for the binary and compared them to the ephemeris computed by Creevey et al. The comparison shows marginally different results. In particular, a change in the systemic velocity by −2 km s{sup −1} is suggested by our results. We compare this systemic velocity difference to that expected due to reflex motion of the binary in response to the third body in the system. The systemic velocity difference is consistent with reflex motion, given our mass determination for the eclipsing binary and the orbital parameters determined by Volkov and Volkova for the three-body orbit. We see no evidence for the third body in our spectra, but we do see strong interstellar Na D lines that are consistent in strength with the direction and expected distance of V577 Oph.

A New Orbit for the Eclipsing Binary V577 Oph

Science.gov (United States)

Jeffery, Elizabeth J.; Barnes, Thomas G., III; Skillen, Ian; Montemayor, Thomas J.

2017-09-01

Pulsating stars in eclipsing binary systems are unique objects for providing constraints on stellar models. To fully leverage the information available from the binary system, full orbital radial velocity curves must be obtained. We report 23 radial velocities for components of the eclipsing binary V577 Oph, whose primary star is a δ Sct variable. The velocities cover a nearly complete orbit and a time base of 20 years. We computed orbital elements for the binary and compared them to the ephemeris computed by Creevey et al. The comparison shows marginally different results. In particular, a change in the systemic velocity by -2 km s-1 is suggested by our results. We compare this systemic velocity difference to that expected due to reflex motion of the binary in response to the third body in the system. The systemic velocity difference is consistent with reflex motion, given our mass determination for the eclipsing binary and the orbital parameters determined by Volkov & Volkova for the three-body orbit. We see no evidence for the third body in our spectra, but we do see strong interstellar Na D lines that are consistent in strength with the direction and expected distance of V577 Oph.

Satellite laser ranging to low Earth orbiters: orbit and network validation

Science.gov (United States)

Arnold, Daniel; Montenbruck, Oliver; Hackel, Stefan; Sośnica, Krzysztof

2018-04-01

Satellite laser ranging (SLR) to low Earth orbiters (LEOs) provides optical distance measurements with mm-to-cm-level precision. SLR residuals, i.e., differences between measured and modeled ranges, serve as a common figure of merit for the quality assessment of orbits derived by radiometric tracking techniques. We discuss relevant processing standards for the modeling of SLR observations and highlight the importance of line-of-sight-dependent range corrections for the various types of laser retroreflector arrays. A 1-3 cm consistency of SLR observations and GPS-based precise orbits is demonstrated for a wide range of past and present LEO missions supported by the International Laser Ranging Service (ILRS). A parameter estimation approach is presented to investigate systematic orbit errors and it is shown that SLR validation of LEO satellites is not only able to detect radial but also along-track and cross-track offsets. SLR residual statistics clearly depend on the employed precise orbit determination technique (kinematic vs. reduced-dynamic, float vs. fixed ambiguities) but also reveal pronounced differences in the ILRS station performance. Using the residual-based parameter estimation approach, corrections to ILRS station coordinates, range biases, and timing offsets are derived. As a result, root-mean-square residuals of 5-10 mm have been achieved over a 1-year data arc in 2016 using observations from a subset of high-performance stations and ambiguity-fixed orbits of four LEO missions. As a final contribution, we demonstrate that SLR can not only validate single-satellite orbit solutions but also precise baseline solutions of formation flying missions such as GRACE, TanDEM-X, and Swarm.

Orbital glass in HTSC

International Nuclear Information System (INIS)

Kusmartsev, F.V.

1992-10-01

The physical reasons why the orbital glass may exist in granular high-temperature superconductors and the existing experimental data appeared recently are discussed. The orbital glass is characterized by the coexistence of the orbital paramagnetic state with the superconducting state and occurs at small magnetic fields H c0 c1 . The transition in orbital glass arises at the critical field H c0 which is inversely proportional to the surface cross-area S of an average grain. In connection with theoretical predictions the possible experiments are proposed. (author). 10 refs

The Mars Reconnaissance Orbiter Mission: 10 Years of Exploration from Mars Orbit

Science.gov (United States)

Johnston, M. Daniel; Zurek, Richard W.

2016-01-01

The Mars Reconnaissance Orbiter ( MRO ) entered Mars orbit on March 10, 2006. After five months of aerobraking, a series of propulsive maneuvers were used to establish the desired low -altitude science orbit. The spacecraft has been on station in its 255 x 320 k m, sun -synchronous (approximately 3 am -pm ), primary science orbit since September 2006 performing both scientific and Mars programmatic support functions. This paper will provide a summary of the major achievements of the mission to date and the major flight activities planned for the remainder of its third Extended Mission (EM3). Some of the major flight challenges the flight team has faced are also discussed.

Orbital Infarction due to Sickle Cell Disease without Orbital Pain

Directory of Open Access Journals (Sweden)

Cameron L. McBride

2016-01-01

Full Text Available Sickle cell disease is a hemoglobinopathy that results in paroxysmal arteriolar occlusion and tissue infarction that can manifest in a plurality of tissues. Rarely, these infarcted crises manifest in the bony orbit. Orbital infarction usually presents with acute onset of periorbital tenderness, swelling, erythema, and pain. Soft tissue swelling can result in proptosis and attenuation of extraocular movements. Expedient diagnosis of sickle cell orbital infarction is crucial because this is a potentially sight-threatening entity. Diagnosis can be delayed since the presentation has physical and radiographic findings mimicking various infectious and traumatic processes. We describe a patient who presented with sickle cell orbital crisis without pain. This case highlights the importance of maintaining a high index of suspicion in patients with known sickle cell disease or of African descent born outside the United States in a region where screening for hemoglobinopathy is not routine, even when the presentation is not classic.

Hanging on for the ride: adhesion to the extracellular matrix mediates cellular responses in skeletal muscle morphogenesis and disease.

Science.gov (United States)

Goody, Michelle F; Sher, Roger B; Henry, Clarissa A

2015-05-01

Skeletal muscle specification and morphogenesis during early development are critical for normal physiology. In addition to mediating locomotion, skeletal muscle is a secretory organ that contributes to metabolic homeostasis. Muscle is a highly adaptable tissue, as evidenced by the ability to increase muscle cell size and/or number in response to weight bearing exercise. Conversely, muscle wasting can occur during aging (sarcopenia), cancer (cancer cachexia), extended hospital stays (disuse atrophy), and in many genetic diseases collectively known as the muscular dystrophies and myopathies. It is therefore of great interest to understand the cellular and molecular mechanisms that mediate skeletal muscle development and adaptation. Muscle morphogenesis transforms short muscle precursor cells into long, multinucleate myotubes that anchor to tendons via the myotendinous junction. This process requires carefully orchestrated interactions between cells and their extracellular matrix microenvironment. These interactions are dynamic, allowing muscle cells to sense biophysical, structural, organizational, and/or signaling changes within their microenvironment and respond appropriately. In many musculoskeletal diseases, these cell adhesion interactions are disrupted to such a degree that normal cellular adaptive responses are not sufficient to compensate for accumulating damage. Thus, one major focus of current research is to identify the cell adhesion mechanisms that drive muscle morphogenesis, with the hope that understanding how muscle cell adhesion promotes the intrinsic adaptability of muscle tissue during development may provide insight into potential therapeutic approaches for muscle diseases. Our objectives in this review are to highlight recent studies suggesting conserved roles for cell-extracellular matrix adhesion in vertebrate muscle morphogenesis and cellular adaptive responses in animal models of muscle diseases. Copyright © 2015 Elsevier Inc. All rights

Eye and orbital cavity

International Nuclear Information System (INIS)

Panfilova, G.V.; Koval', G.Yu.

1984-01-01

Radioanatomy of eyes and orbit is described. Diseases of the orbit (developmental anomalies, inflammatory diseases, lacrimal apparatus deseases, toxoplasmosis, tumors and cysts et al.), methods of foreign body localization in the eye are considered. Roentgenograms of the orbit and calculation table for foreign body localization in spherical eyes of dissimilar diameter are presented

Local orbit feedback

International Nuclear Information System (INIS)

Anon.

1991-01-01

Critically aligned experiments are sensitive to small changes in the electron beam orbit. At the NSLS storage rings, the electron beam and photon beam motions have been monitored over the past several years. In the survey conducted in 1986 by the NSLS Users Executive Committee, experimenters requested the vertical beam position variation and the vertical angle variation, within a given fill, remain within 10 μm and 10 μr, respectively. This requires improvement in the beam stability by about one order of magnitude. At the NSLS and SSRL storage rings, the beam that is originally centered on the position monitor by a dc orbit correction is observed to have two kinds of motion: a dc drift over a storage period of several hours and a beam bounce about its nominal position. These motions are a result of the equilibrium orbit not being held perfectly stable due to time-varying errors introduced into the magnetic guide field by power supplies, mechanical vibration of the magnets, cooling water temperature variations, etc. The approach to orbit stabilization includes (1) identifying and suppressing as many noise sources on the machine as possible, (2) correcting the beam position globally (see Section 6) by controlling a number of correctors around the circumference of the machine, and (3) correcting the beam position and angle at a given source location by position feedback using local detectors and local orbit bumps. The third approach, called Local Orbit Feedback will be discussed in this section

Matrix effects in nilotinib formulations with pH-responsive polymer produced by carbon dioxide-mediated precipitation

DEFF Research Database (Denmark)

Colombo, Stefano; Brisander, Magnus; Haglöf, Jakob

2015-01-01

Factors determining the pH-controlled dissolution kinetics of nilotinib formulations with the pH-titrable polymer hydroxypropyl methylcellulose phthalate, obtained by carbon dioxide-mediated precipitation, were mechanistically examined in acid and neutral environment. The matrix effect, modulating...... in the polymer matrix were mediated by hydrogen bonding between the drug and the phthalate groups on the polymer. Simultaneous Raman and UV-imaging studies of the effect of drug load on the swelling and dissolution of the polymer matrix revealed that high nilotinib load prevented matrix swelling on passage from...

Oxide_Oxide Ceramic Matrix Composite (CMC) Exhaust Mixer Development in the NASA Environmentally Responsible Aviation (ERA) Project

Science.gov (United States)

Kiser, J. Douglas; Bansal, Narottam P.; Szelagowski, James; Sokhey, Jagdish; Heffernan, Tab; Clegg, Joseph; Pierluissi, Anthony; Riedell, Jim; Wyen, Travis; Atmur, Steven;

Validation of Galileo orbits using SLR with a focus on satellites launched into incorrect orbital planes

Science.gov (United States)

Sośnica, Krzysztof; Prange, Lars; Kaźmierski, Kamil; Bury, Grzegorz; Drożdżewski, Mateusz; Zajdel, Radosław; Hadas, Tomasz

2018-02-01

The space segment of the European Global Navigation Satellite System (GNSS) Galileo consists of In-Orbit Validation (IOV) and Full Operational Capability (FOC) spacecraft. The first pair of FOC satellites was launched into an incorrect, highly eccentric orbital plane with a lower than nominal inclination angle. All Galileo satellites are equipped with satellite laser ranging (SLR) retroreflectors which allow, for example, for the assessment of the orbit quality or for the SLR-GNSS co-location in space. The number of SLR observations to Galileo satellites has been continuously increasing thanks to a series of intensive campaigns devoted to SLR tracking of GNSS satellites initiated by the International Laser Ranging Service. This paper assesses systematic effects and quality of Galileo orbits using SLR data with a main focus on Galileo satellites launched into incorrect orbits. We compare the SLR observations with respect to microwave-based Galileo orbits generated by the Center for Orbit Determination in Europe (CODE) in the framework of the International GNSS Service Multi-GNSS Experiment for the period 2014.0-2016.5. We analyze the SLR signature effect, which is characterized by the dependency of SLR residuals with respect to various incidence angles of laser beams for stations equipped with single-photon and multi-photon detectors. Surprisingly, the CODE orbit quality of satellites in the incorrect orbital planes is not worse than that of nominal FOC and IOV orbits. The RMS of SLR residuals is even lower by 5.0 and 1.5 mm for satellites in the incorrect orbital planes than for FOC and IOV satellites, respectively. The mean SLR offsets equal -44.9, -35.0, and -22.4 mm for IOV, FOC, and satellites in the incorrect orbital plane. Finally, we found that the empirical orbit models, which were originally designed for precise orbit determination of GNSS satellites in circular orbits, provide fully appropriate results also for highly eccentric orbits with variable linear

Calculation of the electronic and magnetic structures of 3d impurities in the Hcp Fe matrix

International Nuclear Information System (INIS)

Franca, Fernando

1995-01-01

In this work we investigate the local magnetic properties and the electronic structure of HCP Fe, as well introducing transition metals atoms 3d (Cs, Ti, Cr, Mn, Co, Ni, Cu, Zn) in HCP iron matrix. We employed the discrete variational method (DVM), which is an orbital molecular method which incorporate the Hartree-Fock-Slater theory and the linear combination of atomic orbitals (LCAO), in the self-consistent charge approximation and the local density approximation of Von Barth and Hedin to the exchange-correlation potential. We used the embedded cluster model to investigate the electronic structure and the local magnetic properties for the central atom of a cluster of 27 atoms immersed in the microcrystal representing the HCP Fe. (author)

Orbital preservation in a maxillectomy

Energy Technology Data Exchange (ETDEWEB)

Tanaka, Katsuhiko; Nishikawa, Hitomi; Kumagai, Masahiko; Dosaka, Yoshihiro; Kuroda, Toru; Atago, Yoshihiro; Nishio, Masamichi [Sapporo National Hospital (Japan)

1999-07-01

In the past 9 years, 38 patients of the maxillary cancer were treated by a combination of radiation and surgery. Sixteen patients showed the orbital involvement as confirmed by a CT scan and/or MRI. An orbital excenteration was necessary in 6 patients, due mainly to deep intraorbital invasion, while in 10, the orbital contents were preserved despite the involvement of the orbital capsule. The local rate of the orbital region in the latter patients evaluated at 48 months after the initial surgery was 44%. For the treatment of the recurrence at the orbital capsule. The application of gold grain (Au{sup 198}) thus appeared to be a useful tool for further preserving the eye. (author)

Orbital preservation in a maxillectomy

International Nuclear Information System (INIS)

Tanaka, Katsuhiko; Nishikawa, Hitomi; Kumagai, Masahiko; Dosaka, Yoshihiro; Kuroda, Toru; Atago, Yoshihiro; Nishio, Masamichi

1999-01-01

In the past 9 years, 38 patients of the maxillary cancer were treated by a combination of radiation and surgery. Sixteen patients showed the orbital involvement as confirmed by a CT scan and/or MRI. An orbital excenteration was necessary in 6 patients, due mainly to deep intraorbital invasion, while in 10, the orbital contents were preserved despite the involvement of the orbital capsule. The local rate of the orbital region in the latter patients evaluated at 48 months after the initial surgery was 44%. For the treatment of the recurrence at the orbital capsule. The application of gold grain (Au 198 ) thus appeared to be a useful tool for further preserving the eye. (author)

Specification of matrix cleanup goals in fractured porous media.

Science.gov (United States)

Rodríguez, David J; Kueper, Bernard H

2013-01-01

Semianalytical transient solutions have been developed to evaluate what level of fractured porous media (e.g., bedrock or clay) matrix cleanup must be achieved in order to achieve compliance of fracture pore water concentrations within a specified time at specified locations of interest. The developed mathematical solutions account for forward and backward diffusion in a fractured porous medium where the initial condition comprises a spatially uniform, nonzero matrix concentration throughout the domain. Illustrative simulations incorporating the properties of mudstone fractured bedrock demonstrate that the time required to reach a desired fracture pore water concentration is a function of the distance between the point of compliance and the upgradient face of the domain where clean groundwater is inflowing. Shorter distances correspond to reduced times required to reach compliance, implying that shorter treatment zones will respond more favorably to remediation than longer treatment zones in which back-diffusion dominates the fracture pore water response. For a specified matrix cleanup goal, compliance of fracture pore water concentrations will be reached sooner for decreased fracture spacing, increased fracture aperture, higher matrix fraction organic carbon, lower matrix porosity, shorter aqueous phase decay half-life, and a higher hydraulic gradient. The parameters dominating the response of the system can be measured using standard field and laboratory techniques. © 2012, The Author(s). Ground Water © 2012, National Ground Water Association.

The Coupled Orbit-Attitude Dynamics and Control of Electric Sail in Displaced Solar Orbits

Directory of Open Access Journals (Sweden)

Mingying Huo

2017-01-01

Full Text Available Displaced solar orbits for spacecraft propelled by electric sails are investigated. Since the propulsive thrust is induced by the sail attitude, the orbital and attitude dynamics of electric-sail-based spacecraft are coupled and required to be investigated together. However, the coupled dynamics and control of electric sails have not been discussed in most published literatures. In this paper, the equilibrium point of the coupled dynamical system in displaced orbit is obtained, and its stability is analyzed through a linearization. The results of stability analysis show that only some of the orbits are marginally stable. For unstable displaced orbits, linear quadratic regulator is employed to control the coupled attitude-orbit system. Numerical simulations show that the proposed strategy can control the coupled system and a small torque can stabilize both the attitude and orbit. In order to generate the control force and torque, the voltage distribution problem is studied in an optimal framework. The numerical results show that the control force and torque of electric sail can be realized by adjusting the voltage distribution of charged tethers.

Application of orbital strong magnet in the extraction of deep orbital magnetic foreign bodies

Directory of Open Access Journals (Sweden)

Jin-Chen Jia

2017-12-01

Full Text Available AIM: To investigate the surgical method and efficacy of extraction of deep orbital magnetic foreign bodies by mean of an orbital strong magnet. METHODS: A retrospective analysis of clinical data of patients with deep orbital magnetic foreign bodies(OMFBin Hebei Eye Hospital from June 2014 to May 2017 was processed. A total of 23 eyes were enrolled, among them, 14 eyes of extraorbital OMFB, 9 eyes of intraorbital OMFB. The rate of extraction of foreign bodies and the postoperative complications were observed. RESULTS: All eyes of intraorbital foreign bodies were successfully extracted with 100% success rate. Twelve of 14 eyes of extraorbital foreign bodies were extracted with 86% success rate. Mild orbital hemorrhage were found in 2 eyes. There was no other obvious complication such as visual loss, orbital massive hemorrhage or limited ocular movement. CONCLUSION: It's an ideal surgical method to extract the deep orbital magnetic foreign bodies by mean of an orbital strong magnet, with mini-injury, high success rate, short duration and few complications.

Atomic orbital-based SOS-MP2 with tensor hypercontraction. I. GPU-based tensor construction and exploiting sparsity

Energy Technology Data Exchange (ETDEWEB)

Song, Chenchen; Martínez, Todd J. [Department of Chemistry and the PULSE Institute, Stanford University, Stanford, California 94305 (United States); SLAC National Accelerator Laboratory, Menlo Park, California 94025 (United States)

2016-05-07

We present a tensor hypercontracted (THC) scaled opposite spin second order Møller-Plesset perturbation theory (SOS-MP2) method. By using THC, we reduce the formal scaling of SOS-MP2 with respect to molecular size from quartic to cubic. We achieve further efficiency by exploiting sparsity in the atomic orbitals and using graphical processing units (GPUs) to accelerate integral construction and matrix multiplication. The practical scaling of GPU-accelerated atomic orbital-based THC-SOS-MP2 calculations is found to be N{sup 2.6} for reference data sets of water clusters and alanine polypeptides containing up to 1600 basis functions. The errors in correlation energy with respect to density-fitting-SOS-MP2 are less than 0.5 kcal/mol for all systems tested (up to 162 atoms).

Atomic orbital-based SOS-MP2 with tensor hypercontraction. I. GPU-based tensor construction and exploiting sparsity.

Science.gov (United States)

Song, Chenchen; Martínez, Todd J

2016-05-07

We present a tensor hypercontracted (THC) scaled opposite spin second order Møller-Plesset perturbation theory (SOS-MP2) method. By using THC, we reduce the formal scaling of SOS-MP2 with respect to molecular size from quartic to cubic. We achieve further efficiency by exploiting sparsity in the atomic orbitals and using graphical processing units (GPUs) to accelerate integral construction and matrix multiplication. The practical scaling of GPU-accelerated atomic orbital-based THC-SOS-MP2 calculations is found to be N(2.6) for reference data sets of water clusters and alanine polypeptides containing up to 1600 basis functions. The errors in correlation energy with respect to density-fitting-SOS-MP2 are less than 0.5 kcal/mol for all systems tested (up to 162 atoms).

Congenital orbital teratoma.

Science.gov (United States)

Aiyub, Shereen; Chan, Wengonn; Szetu, John; Sullivan, Laurence J; Pater, John; Cooper, Peter; Selva, Dinesh

2013-12-01

We present a case of mature congenital orbital teratoma managed with lid-sparing exenteration and dermis fat graft. This is a case report on the management of congenital orbital teratoma. A full-term baby was born in Fiji with prolapsed right globe which was surrounded by a nonpulsatile, cystic mass. Clinical and imaging features were consistent with congenital orbital teratoma. Due to limited surgical expertise, the patient was transferred to Adelaide, Australia for further management. The patient underwent a lid-sparing exenteration with frozen section control of the apical margin. A dermis fat graft from the groin was placed beneath the lid skin to provide volume. Histopathology revealed mature tissues from each of the three germ cell layers which confirmed the diagnosis of mature teratoma. We describe the successful use of demis fat graft in socket reconstruction following lid-sparing exenteration for congenital orbital teratoma.

Congenital orbital teratoma

Directory of Open Access Journals (Sweden)

Shereen Aiyub

2013-01-01

Full Text Available We present a case of mature congenital orbital teratoma managed with lid-sparing exenteration and dermis fat graft. This is a case report on the management of congenital orbital teratoma. A full-term baby was born in Fiji with prolapsed right globe which was surrounded by a nonpulsatile, cystic mass. Clinical and imaging features were consistent with congenital orbital teratoma. Due to limited surgical expertise, the patient was transferred to Adelaide, Australia for further management. The patient underwent a lid-sparing exenteration with frozen section control of the apical margin. A dermis fat graft from the groin was placed beneath the lid skin to provide volume. Histopathology revealed mature tissues from each of the three germ cell layers which confirmed the diagnosis of mature teratoma. We describe the successful use of demis fat graft in socket reconstruction following lid-sparing exenteration for congenital orbital teratoma.

Detecting a Subsurface Ocean From Periodic Orbits at Enceladus

Science.gov (United States)

Casotto, S.; Padovan, S.; Russell, R. P.; Lara, M.

2008-12-01

from the tiger- stripes. Near-circular, low altitude highly inclined orbits with arbitrary initial conditions will impact Enceladus if uncontrolled in about 1 to 2 days. To reduce risk and station-keeping requirements we choose periodic orbits in the Hill's plus non-spherical Enceladus model. Despite the instability, the repeat ground track solutions represent equilibria in the dominant terms of the dynamics and therefore extend the uncontrolled lifetimes to ~7 to ~10 days. Round-trip transfers between the two orbital phases is expected to conservatively cost between ~50 and ~100 m/s. We use orbits of different altitudes and inclinations to simulate Earth-based ranging to the orbiter and altimeter measurements to the surface of Enceladus. The simulations are made assuming different tidal responses by adopting different values of the Love numbers. The synthetic measurements are then inverted and the tidal parameters h2 and k2 estimated. Results will be presented in terms of sensitivity of detection of Love numbers to the different orbital geometries. Indications will thus be provided for optimized orbit planning of future exploration missions aimed at investigating the internal structure of the satellite and the detection of its putative subcrustal ocean.

In vitro extracellular matrix model to evaluate stroma cell response to transvaginal mesh.

Science.gov (United States)

Wu, Ming-Ping; Huang, Kuan-Hui; Long, Cheng-Yu; Yang, Chau-Chen; Tong, Yat-Ching

2014-04-01

The use of surgical mesh for female pelvic floor reconstruction has increased in recent years. However, there is paucity of information about the biological responses of host stroma cells to different meshes. This study was aimed to establish an in vitro experimental model to study the micro-environment of extracellular matrix (ECM) with embedded mesh and the stroma cell behaviors to different synthetic meshes. Matrigel multi-cellular co-culture system with embedded mesh was used to evaluate the interaction of stroma cells and synthetic mesh in a simulated ECM environment. Human umbilical vein endothelial cells (HUVEC) and NIH3T3 fibroblasts were inoculated in the system. The established multi-cellular Matrigel co-culture system was used to detect stroma cell recruitment and tube formation ability for different synthetic meshes. HUVEC and NIH3T3 cells were recruited into the mesh interstices and organized into tube-like structures in type I mesh material from Perigee, Marlex and Prolift 24 hr after cell inoculation. On the contrary, there was little recruitment of HUVEC and NIH3T3 cells into the type III mesh of intra-vaginal sling (IVS). The Matrigel multi-cellular co-culture system with embedded mesh offers a useful in vitro model to study the biological behaviors of stroma cells in response to different types of synthetic meshes. The system can help to select ideal mesh candidates before actual implantation into the human body. © 2013 Wiley Periodicals, Inc.

Orbit Determination of Spacecraft in Earth-Moon L1 and L2 Libration Point Orbits

Science.gov (United States)

Woodard, Mark; Cosgrove, Daniel; Morinelli, Patrick; Marchese, Jeff; Owens, Brandon; Folta, David

2011-01-01

The ARTEMIS mission, part of the THEMIS extended mission, is the first to fly spacecraft in the Earth-Moon Lissajous regions. In 2009, two of the five THEMIS spacecraft were redeployed from Earth-centered orbits to arrive in Earth-Moon Lissajous orbits in late 2010. Starting in August 2010, the ARTEMIS P1 spacecraft executed numerous stationkeeping maneuvers, initially maintaining a lunar L2 Lissajous orbit before transitioning into a lunar L1 orbit. The ARTEMIS P2 spacecraft entered a L1 Lissajous orbit in October 2010. In April 2011, both ARTEMIS spacecraft will suspend Lissajous stationkeeping and will be maneuvered into lunar orbits. The success of the ARTEMIS mission has allowed the science team to gather unprecedented magnetospheric measurements in the lunar Lissajous regions. In order to effectively perform lunar Lissajous stationkeeping maneuvers, the ARTEMIS operations team has provided orbit determination solutions with typical accuracies on the order of 0.1 km in position and 0.1 cm/s in velocity. The ARTEMIS team utilizes the Goddard Trajectory Determination System (GTDS), using a batch least squares method, to process range and Doppler tracking measurements from the NASA Deep Space Network (DSN), Berkeley Ground Station (BGS), Merritt Island (MILA) station, and United Space Network (USN). The team has also investigated processing of the same tracking data measurements using the Orbit Determination Tool Kit (ODTK) software, which uses an extended Kalman filter and recursive smoother to estimate the orbit. The orbit determination results from each of these methods will be presented and we will discuss the advantages and disadvantages associated with using each method in the lunar Lissajous regions. Orbit determination accuracy is dependent on both the quality and quantity of tracking measurements, fidelity of the orbit force models, and the estimation techniques used. Prior to Lissajous operations, the team determined the appropriate quantity of tracking

Multiplicity dependence of matrix-induced frequency shifts for atomic transitions of the group 12 metals in rare gas solids

International Nuclear Information System (INIS)

Laursen, S.L.; Cartland, H.E.

1991-01-01

Atomic resonances of the group 12 metal atoms, Hg, Cd, and Zn, undergo frequency shifts from the gas phase atomic line when trapped in rare gas matrices of Ar, Kr, and Xe at 12 K. As expected, the shifts are approximately linear in polarizability of the rare gas, but the slope of this line depends on whether the transition in question is 1 P 1 left-arrow 1 S 0 or 3 P 1 left-arrow 1 S 0 . Thus the matrix-induced frequency shift is dependent on the singlet or triplet nature of the excited state as well as on the matrix material. This dependence on multiplicity is discussed in terms of interactions between the excited-state atomic orbitals and the matrix. The results are compared to matrix studies of other metals and to related gas-phase work on diatomic van der Waals complexes of group 12 metals with rare gases

PARTITIONING TUNGSTEN BETWEEN MATRIX PRECURSORS AND CHONDRULE PRECURSORS THROUGH RELATIVE SETTLING

Energy Technology Data Exchange (ETDEWEB)

Hubbard, Alexander, E-mail: ahubbard@amnh.org [American Museum of Natural History, New York, NY (United States)

2016-08-01

Recent studies of chondrites have found a tungsten isotopic anomaly between chondrules and matrix. Given the refractory nature of tungsten, this implies that W was carried into the solar nebula by at least two distinct families of pre-solar grains. The observed chondrule/matrix split requires that the distinct families were kept separate during the dust coagulation process, and that the two families of grain interacted with the chondrule formation mechanism differently. We take the co-existence of different families of solids in the same general orbital region at the chondrule-precursor size as given, and explore the requirements for them to have interacted with the chondrule formation process at significantly different rates. We show that this sorting of families of solids into chondrule- and matrix-destined dust had to have been at least as powerful a sorting mechanism as the relative settling of aerodynamically distinct grains at least two scale heights above the midplane. The requirement that the chondrule formation mechanism was correlated in some fashion with a dust-grain sorting mechanism argues strongly for spatially localized chondrule formation mechanisms such as turbulent dissipation in non-thermally ionized disk surface layers, and argues against volume-filling mechanisms such as planetesimal bow shocks.

PARTITIONING TUNGSTEN BETWEEN MATRIX PRECURSORS AND CHONDRULE PRECURSORS THROUGH RELATIVE SETTLING

International Nuclear Information System (INIS)

Hubbard, Alexander

2016-01-01

Recent studies of chondrites have found a tungsten isotopic anomaly between chondrules and matrix. Given the refractory nature of tungsten, this implies that W was carried into the solar nebula by at least two distinct families of pre-solar grains. The observed chondrule/matrix split requires that the distinct families were kept separate during the dust coagulation process, and that the two families of grain interacted with the chondrule formation mechanism differently. We take the co-existence of different families of solids in the same general orbital region at the chondrule-precursor size as given, and explore the requirements for them to have interacted with the chondrule formation process at significantly different rates. We show that this sorting of families of solids into chondrule- and matrix-destined dust had to have been at least as powerful a sorting mechanism as the relative settling of aerodynamically distinct grains at least two scale heights above the midplane. The requirement that the chondrule formation mechanism was correlated in some fashion with a dust-grain sorting mechanism argues strongly for spatially localized chondrule formation mechanisms such as turbulent dissipation in non-thermally ionized disk surface layers, and argues against volume-filling mechanisms such as planetesimal bow shocks.

Dynamic culture substrate that captures a specific extracellular matrix protein in response to light

International Nuclear Information System (INIS)

Nakanishi, Jun; Nakayama, Hidekazu; Horiike, Yasuhiro; Yamaguchi, Kazuo; Garcia, Andres J

2011-01-01

The development of methods for the off-on switching of immobilization or presentation of cell-adhesive peptides and proteins during cell culture is important because such surfaces are useful for the analysis of the dynamic processes of cell adhesion and migration. This paper describes a chemically functionalized gold substrate that captures a genetically tagged extracellular matrix protein in response to light. The substrate was composed of mixed self-assembled monolayers (SAMs) of three disulfide compounds containing (i) a photocleavable poly(ethylene glycol) (PEG), (ii) nitrilotriacetic acid (NTA) and (iii) hepta(ethylene glycol) (EG 7 ). Although the NTA group has an intrinsic high affinity for oligohistidine tag (His-tag) sequences in its Ni 2+ -ion complex, the interaction was suppressed by the steric hindrance of coexisting PEG on the substrate surface. Upon photoirradiation of the substrate to release the PEG chain from the surface, this interaction became possible and hence the protein was captured at the irradiated regions, while keeping the non-specific adsorption of non-His-tagged proteins blocked by the EG 7 underbrush. In this way, we selectively immobilized a His-tagged fibronectin fragment (FNIII 7-10 ) to the irradiated regions. In contrast, when bovine serum albumin-a major serum protein-was added as a non-His-tagged protein, the surface did not permit its capture, with or without irradiation. In agreement with these results, cells were selectively attached to the irradiated patterns only when a His-tagged FNIII 7-10 was added to the medium. These results indicate that the present method is useful for studying the cellular behavior on the specific extracellular matrix protein in cell-culturing environments.

Dynamic culture substrate that captures a specific extracellular matrix protein in response to light

Energy Technology Data Exchange (ETDEWEB)

Nakanishi, Jun; Nakayama, Hidekazu; Horiike, Yasuhiro [World Premier International (WPI) Research Center Initiative, International Center for Materials Nanoarchitectonics (MANA), National Institute for Materials Science - NIMS (Japan); Yamaguchi, Kazuo [Department of Chemistry, Faculty of Science and Research Institute for Photofunctionalized Materials, Kanagawa University (Japan); Garcia, Andres J, E-mail: NAKANISHI.Jun@nims.go.jp [Institute for Bioengineering and Bioscience, Woodruff School of Mechanical Engineering, Georgia Institute of Technology (United States)

2011-08-15

The development of methods for the off-on switching of immobilization or presentation of cell-adhesive peptides and proteins during cell culture is important because such surfaces are useful for the analysis of the dynamic processes of cell adhesion and migration. This paper describes a chemically functionalized gold substrate that captures a genetically tagged extracellular matrix protein in response to light. The substrate was composed of mixed self-assembled monolayers (SAMs) of three disulfide compounds containing (i) a photocleavable poly(ethylene glycol) (PEG), (ii) nitrilotriacetic acid (NTA) and (iii) hepta(ethylene glycol) (EG{sub 7}). Although the NTA group has an intrinsic high affinity for oligohistidine tag (His-tag) sequences in its Ni{sup 2+}-ion complex, the interaction was suppressed by the steric hindrance of coexisting PEG on the substrate surface. Upon photoirradiation of the substrate to release the PEG chain from the surface, this interaction became possible and hence the protein was captured at the irradiated regions, while keeping the non-specific adsorption of non-His-tagged proteins blocked by the EG{sub 7} underbrush. In this way, we selectively immobilized a His-tagged fibronectin fragment (FNIII{sub 7-10}) to the irradiated regions. In contrast, when bovine serum albumin-a major serum protein-was added as a non-His-tagged protein, the surface did not permit its capture, with or without irradiation. In agreement with these results, cells were selectively attached to the irradiated patterns only when a His-tagged FNIII{sub 7-10} was added to the medium. These results indicate that the present method is useful for studying the cellular behavior on the specific extracellular matrix protein in cell-culturing environments.

Dynamic culture substrate that captures a specific extracellular matrix protein in response to light

Directory of Open Access Journals (Sweden)

Jun Nakanishi, Hidekazu Nakayama, Kazuo Yamaguchi, Andres J Garcia and Yasuhiro Horiike

2011-01-01

Full Text Available The development of methods for the off–on switching of immobilization or presentation of cell-adhesive peptides and proteins during cell culture is important because such surfaces are useful for the analysis of the dynamic processes of cell adhesion and migration. This paper describes a chemically functionalized gold substrate that captures a genetically tagged extracellular matrix protein in response to light. The substrate was composed of mixed self-assembled monolayers (SAMs of three disulfide compounds containing (i a photocleavable poly(ethylene glycol (PEG, (ii nitrilotriacetic acid (NTA and (iii hepta(ethylene glycol (EG7. Although the NTA group has an intrinsic high affinity for oligohistidine tag (His-tag sequences in its Ni2+-ion complex, the interaction was suppressed by the steric hindrance of coexisting PEG on the substrate surface. Upon photoirradiation of the substrate to release the PEG chain from the surface, this interaction became possible and hence the protein was captured at the irradiated regions, while keeping the non-specific adsorption of non-His-tagged proteins blocked by the EG7 underbrush. In this way, we selectively immobilized a His-tagged fibronectin fragment (FNIII7–10 to the irradiated regions. In contrast, when bovine serum albumin—a major serum protein—was added as a non-His-tagged protein, the surface did not permit its capture, with or without irradiation. In agreement with these results, cells were selectively attached to the irradiated patterns only when a His-tagged FNIII7-10 was added to the medium. These results indicate that the present method is useful for studying the cellular behavior on the specific extracellular matrix protein in cell-culturing environments.

DBDA as a Novel Matrix for the Analyses of Small Molecules and Quantification of Fatty Acids by Negative Ion MALDI-TOF MS.

Science.gov (United States)

Ling, Ling; Li, Ying; Wang, Sheng; Guo, Liming; Xiao, Chunsheng; Chen, Xuesi; Guo, Xinhua

2018-04-01

Matrix interference ions in low mass range has always been a concern when using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) to analyze small molecules (matrix, N1,N4-dibenzylidenebenzene-1,4-diamine (DBDA) was synthesized for the analyses of small molecules by negative ion MALDI-TOF MS. Notably, only neat ions ([M-H] - ) of fatty acids without matrix interference appeared in the mass spectra and the limit of detection (LOD) reached 0.3 fmol. DBDA also has great performance towards other small molecules such as amino acids, peptides, and nucleotide. Furthermore, with this novel matrix, the free fatty acids in serum were quantitatively analyzed based on the correlation curves with correlation coefficient of 0.99. In addition, UV-Vis experiments and molecular orbital calculations were performed to explore mechanism about DBDA used as matrix in the negative ion mode. The present work shows that the DBDA matrix is a highly sensitive matrix with few interference ions for analysis of small molecules. Meanwhile, DBDA is able to precisely quantify the fatty acids in real biological samples. Graphical Abstract ᅟ.

Space Gravity Spectroscopy - determination of the Earth’s gravitational field by means of Newton interpolated LEO ephemeris Case studies on dynamic (CHAMP Rapid Science Orbit and kinematic orbits

Directory of Open Access Journals (Sweden)

T. Reubelt

2003-01-01

Full Text Available An algorithm for the (kinematic orbit analysis of a Low Earth Orbiting (LEO GPS tracked satellite to determine the spherical harmonic coefficients of the terrestrial gravitational field is presented. A contribution to existing long wavelength gravity field models is expected since the kinematic orbit of a LEO satellite can nowadays be determined with very high accuracy in the range of a few centimeters. To demonstrate the applicability of the proposed method, first results from the analysis of real CHAMP Rapid Science (dynamic Orbits (RSO and kinematic orbits are illustrated. In particular, we take advantage of Newton’s Law of Motion which balances the acceleration vector and the gradient of the gravitational potential with respect to an Inertial Frame of Reference (IRF. The satellite’s acceleration vector is determined by means of the second order functional of Newton’s Interpolation Formula from relative satellite ephemeris (baselines with respect to the IRF. Therefore the satellite ephemeris, which are normally given in a Body fixed Frame of Reference (BRF have to be transformed into the IRF. Subsequently the Newton interpolated accelerations have to be reduced for disturbing gravitational and non-gravitational accelerations in order to obtain the accelerations caused by the Earth’s gravitational field. For a first insight in real data processing these reductions have been neglected. The gradient of the gravitational potential, conventionally expressed in vector-valued spherical harmonics and given in a Body Fixed Frame of Reference, must be transformed from BRF to IRF by means of the polar motion matrix, the precession-nutation matrices and the Greenwich Siderial Time Angle (GAST. The resulting linear system of equations is solved by means of a least squares adjustment in terms of a Gauss-Markov model in order to estimate the spherical harmonics coefficients of the Earth’s gravitational field.Key words. space gravity spectroscopy

Conductance of two-dimensional waveguide in presence of the Rashba spin-orbit interaction

Science.gov (United States)

Liu, Duan-Yang; Xia, Jian-Bai

2018-04-01

By using the transfer matrix method, we investigated spin transport in some straight structures in presence of the Rashba spin-orbit interaction. It is proved that the interference of two spin states is the same as that in one-dimensional Datta-Das spin field-effect transistor. The conductance of these structures has been calculated. Conductance quantization is common in these waveguides when we change the Fermi energy and the width of the waveguide. Using a periodic system of quadrate stubs and changing the Fermi energy, a nearly square-wave conductance can be obtained in some regions of the Fermi energy.

Matrix product operators, matrix product states, and ab initio density matrix renormalization group algorithms

Science.gov (United States)

Chan, Garnet Kin-Lic; Keselman, Anna; Nakatani, Naoki; Li, Zhendong; White, Steven R.

2016-07-01

Current descriptions of the ab initio density matrix renormalization group (DMRG) algorithm use two superficially different languages: an older language of the renormalization group and renormalized operators, and a more recent language of matrix product states and matrix product operators. The same algorithm can appear dramatically different when written in the two different vocabularies. In this work, we carefully describe the translation between the two languages in several contexts. First, we describe how to efficiently implement the ab initio DMRG sweep using a matrix product operator based code, and the equivalence to the original renormalized operator implementation. Next we describe how to implement the general matrix product operator/matrix product state algebra within a pure renormalized operator-based DMRG code. Finally, we discuss two improvements of the ab initio DMRG sweep algorithm motivated by matrix product operator language: Hamiltonian compression, and a sum over operators representation that allows for perfect computational parallelism. The connections and correspondences described here serve to link the future developments with the past and are important in the efficient implementation of continuing advances in ab initio DMRG and related algorithms.

A Biofilm Matrix-Associated Protease Inhibitor Protects Pseudomonas aeruginosa from Proteolytic Attack.

Science.gov (United States)

Tseng, Boo Shan; Reichhardt, Courtney; Merrihew, Gennifer E; Araujo-Hernandez, Sophia A; Harrison, Joe J; MacCoss, Michael J; Parsek, Matthew R

2018-04-10

Pseudomonas aeruginosa produces an extracellular biofilm matrix that consists of nucleic acids, exopolysaccharides, lipid vesicles, and proteins. In general, the protein component of the biofilm matrix is poorly defined and understudied relative to the other major matrix constituents. While matrix proteins have been suggested to provide many functions to the biofilm, only proteins that play a structural role have been characterized thus far. Here we identify proteins enriched in the matrix of P. aeruginosa biofilms. We then focused on a candidate matrix protein, the serine protease inhibitor ecotin (PA2755). This protein is able to inhibit neutrophil elastase, a bactericidal enzyme produced by the host immune system during P. aeruginosa biofilm infections. We show that ecotin binds to the key biofilm matrix exopolysaccharide Psl and that it can inhibit neutrophil elastase when associated with Psl. Finally, we show that ecotin protects both planktonic and biofilm P. aeruginosa cells from neutrophil elastase-mediated killing. This may represent a novel mechanism of protection for biofilms to increase their tolerance against the innate immune response. IMPORTANCE Proteins associated with the extracellular matrix of bacterial aggregates called biofilms have long been suggested to provide many important functions to the community. To date, however, only proteins that provide structural roles have been described, and few matrix-associated proteins have been identified. We developed a method to identify matrix proteins and characterized one. We show that this protein, when associated with the biofilm matrix, can inhibit a bactericidal enzyme produced by the immune system during infection and protect biofilm cells from death induced by the enzyme. This may represent a novel mechanism of protection for biofilms, further increasing their tolerance against the immune response. Together, our results are the first to show a nonstructural function for a confirmed matrix

Responsibility and Sustainability in a Food Chain: A Priority Matrix Analysis

Directory of Open Access Journals (Sweden)

Francesco Caracciolo

2011-12-01

Full Text Available  This paper shows the results of empirical research conducted to assess the sustainability of a typical food supply chain, suggesting feasible solutions to satisfy inter-dimensional requisites of durable development. The analysis was conducted with reference to the supply chain of the San Marzano tomato (SMZ, a typical local food. The product is endowed with an origin certification label (PDO, meeting demand within high-value market niches. The SMZ is a flagship product in the Italian region of Campania and has benefited from several regionally funded interventions, such as genetic research and support for the application for EU certification of origin. Two key findings emerged from the research. First, the results allowed us to define a Stakeholder Priority and Responsibilities’ Matrix (SPRM, and monitor the sustainability trend of SMZ food supply chains. Second, the consistency between the adoption of quality strategy (brand of origin and sustainable development of the sector was evaluated. Despite its intrinsic characteristics and its organized, well-defined structure, the SMZ food supply chain is unable to address sustainable objectives without considerable public intervention and support. In terms of sustainability, to be able to show desirable food chain characteristics, the existence of a fully collaborative relationship between the actors has to be ascertained. Identifying shared goals is essential to assign and implement coordinated actions, pooling responsibility for product quality into social and environmental dimensions.

Radiology of orbital trauma

International Nuclear Information System (INIS)

Kelly, J.K.; Lazo, A.; Metes, J.J.

1988-01-01

Computed tomography has become the gold standard against which to measure orbital imaging modalities. The simultaneous display of bone, soft tissues, paranasal sinuses, and intracranial structures is a unique advantage. Radiation dose and cost have been cited as disadvantages. These would suggest that CT be reserved for the patient with significant orbital injury or difficult diagnostic problems. Magnetic resonance is limited in the investigation of orbital trauma

Matrix metalloproteinases in acute coronary syndromes: current perspectives.

Science.gov (United States)

Kampoli, Anna-Maria; Tousoulis, Dimitris; Papageorgiou, Nikolaos; Antoniades, Charalambos; Androulakis, Emmanuel; Tsiamis, Eleftherios; Latsios, George; Stefanadis, Christodoulos

2012-01-01

Matrix metalloproteinases (MMPs) are a family of zinc metallo-endopeptidases secreted by cells and are responsible for much of the turnover of matrix components. Several studies have shown that MMPs are involved in all stages of the atherosclerotic process, from the initial lesion to plaque rupture. Recent evidence suggests that MMP activity may facilitate atherosclerosis, plaque destabilization, and platelet aggregation. In the heart, matrix metalloproteinases participate in vascular remodeling, plaque instability, and ventricular remodelling after cardiac injury. The aim of the present article is to review the structure, function, regulation of MMPs and to discuss their potential role in the pathogenesis of acute coronary syndromes, as well as their contribution and usefullness in the setting of the disease.

Manipulating femtosecond spin-orbit torques with laser pulse sequences to control magnetic memory states and ringing

Science.gov (United States)

Lingos, P. C.; Wang, J.; Perakis, I. E.

2015-05-01

Femtosecond (fs) coherent control of collective order parameters is important for nonequilibrium phase dynamics in correlated materials. Here, we propose such control of ferromagnetic order based on using nonadiabatic optical manipulation of electron-hole (e -h ) photoexcitations to create fs carrier-spin pulses with controllable direction and time profile. These spin pulses are generated due to the time-reversal symmetry breaking arising from nonperturbative spin-orbit and magnetic exchange couplings of coherent photocarriers. By tuning the nonthermal populations of exchange-split, spin-orbit-coupled semiconductor band states, we can excite fs spin-orbit torques that control complex magnetization pathways between multiple magnetic memory states. We calculate the laser-induced fs magnetic anisotropy in the time domain by using density matrix equations of motion rather than the quasiequilibrium free energy. By comparing to pump-probe experiments, we identify a "sudden" out-of-plane magnetization canting displaying fs magnetic hysteresis, which agrees with switchings measured by the static Hall magnetoresistivity. This fs transverse spin-canting switches direction with magnetic state and laser frequency, which distinguishes it from the longitudinal nonlinear optical and demagnetization effects. We propose that sequences of clockwise or counterclockwise fs spin-orbit torques, photoexcited by shaping two-color laser-pulse sequences analogous to multidimensional nuclear magnetic resonance (NMR) spectroscopy, can be used to timely suppress or enhance magnetic ringing and switching rotation in magnetic memories.

Application of the RT-0 nodal methods and NRMPO matrix-response to the cycles 1 and 2 of the LVC

International Nuclear Information System (INIS)

Delfin L, A.; Hernandez L, H.; Alonso V, G.

2005-01-01

The nodal methods the same as that of matrix-response are used to develop numeric calculations, so much in static as dynamics of reactors, in one, two and three dimensions. The topic of this work is to apply the equations modeled in the RPM0 program, obtained when using the nodal scheme RT-0 (Raviart-Thomas index zero) in the neutron diffusion equation in stationary state X Y geometry, applying finite differences centered in mesh and lineal reactivity; also, to use those equations captured in the NRMPO program developed by E. Malambu that uses the matrix-response method in X Y geometry. The numeric results of the radial distribution of power by fuel assembly of the unit 1, in the cycles 1 and 2 of the CLV obtained by both methods, they are compared with the calculations obtained with the CM-PRESTO code that is a neutronic-thermo hydraulic simulator in three dimensions. The comparison of the radial distribution of power in the cycles 1 and 2 of the CLV with the CM-PRESTO code, it presents for RPM0 maximum errors of 8.2% and 12.4% and for NRMPO 31.2% and 61.3% respectively. The results show that it can be feasible to use the program RPM0 like a quick and efficient tool in the multicycle analysis in the fuel management. (Author)

Engineering a spin-fet: spin-orbit phenomena and spin transport induced by a gate electric field

OpenAIRE

Cardoso, J. L.; Hernández-Saldaña, H.

2012-01-01

In this work, we show that a gate electric field, applied in the base of the field-effect devices, leads to inducing spin-orbit interactions (Rashba and linear Dresselhauss) and confines the transport electrons in a two-dimensional electron gas. On the basis of these phenomena we solve analytically the Pauli equation when the Rashba strength and the linear Dresselhaus one are equal, for a tuning value of the gate electric field $\\mathcal{E}_g^*$. Using the transfer matrix approach, we provide...

Root maturation and dentin–pulp response to enamel matrix derivative in pulpotomized permanent teeth

Directory of Open Access Journals (Sweden)

Sherif S Darwish

2014-01-01

Full Text Available The success of pulpotomy of young permanent teeth depends on the proper selection of dressing materials. This study aimed to evaluate the histological and histomorphometric response of dentin–pulp complex to the enamel matrix derivative (Emdogain® gel compared to that of calcium hydroxide when used as a pulp dressing in immature young permanent dogs’ teeth. Dentin-like tissues bridging the full width of the coronal pulp at the interface between the injured and healthy pulp tissues were seen after 1 month in both groups. With time, the dentin bridge increased in thickness for calcium hydroxide but disintegrated and fully disappeared for Emdogain-treated group. Progressive inflammation and total pulp degeneration were only evident with Emdogain-treated group. The root apices of Emdogain-treated teeth became matured and closed by cementum that attached to new alveolar bone by a well-oriented periodontal ligament. In young permanent dentition, Emdogain could be a good candidate for periodontium but not dentino–pulpal complex regeneration.

Manipulation and application of orbital ordering

International Nuclear Information System (INIS)

Sheng Zhigao; Sun Yuping

2014-01-01

Under certain conditions, the orbits of the outmost shell electrons in strong correlated materials can be localized in order, which gives birth to so-called orbital ordering. During the construction or destruction of the orbital ordering, strongly correlated materials show fruitful quantum critical phenomena with great potential for future applications. We first present the mechanism for the construction of orbital ordering. Then, some physical properties associated with orbits are discussed. Finally, we emphasize the key points and progress in the research of orbital ordering controlling. (authors)

Pictorial essay: Orbital tuberculosis

International Nuclear Information System (INIS)

Narula, Mahender K; Chaudhary, Vikas; Baruah, Dhiraj; Kathuria, Manoj; Anand, Rama

2010-01-01

Tuberculosis of the orbit is rare, even in places where tuberculosis is endemic. The disease may involve soft tissue, the lacrimal gland, or the periosteum or bones of the orbital wall. Intracranial extension, in the form of extradural abscess, and infratemporal fossa extension has been described. This pictorial essay illustrates the imaging findings of nine histopathologically confirmed cases of orbital tuberculosis. All these patients responded to antituberculous treatment

Inside the NIKE matrix

OpenAIRE

Brenner, Barbara; Schlegelmilch, Bodo B.; Ambos, Björn

2013-01-01

This case describes how Nike, a consumer goods company with an ever expanding portfolio and a tremendous brand value, manages the tradeoff between local responsiveness and global integration. In particular, the case highlights Nike's organizational structure that consists of a global matrix organization that is replicated at a regional level for the European market. While this organizational structure allows Nike to respond to local consumer tastes it also ensures that the company benefits f...

Traumatic orbital encephalocele: Presentation and imaging.

Science.gov (United States)

Wei, Leslie A; Kennedy, Tabassum A; Paul, Sean; Wells, Timothy S; Griepentrog, Greg J; Lucarelli, Mark J

2016-01-01